Isepäine modernist Toomas Rein / Toomas Rein ; intervjueerinud Mait Väljas ja Reet Varblane

Index Scriptorium Estoniae

Rein, Toomas, 1940-

2010-01-01

23. aprillil avatakse Eesti Arhitektuurimuuseumis arhitekt Toomas Reinu 70. sünnipäevale pühendatud näitus. Kataloogi ja näituse on koostanud Toomas Rein ja Mait Väljas, kujundanud Tiit Jürna. Toomas Rein endast, oma loomingust, eeskujudest, näitusest, nõukogude perioodi hoonete olukorrast, viimase aja töödest, koostööst teiste arhitektidega, teostamata projektidest

Obituary: Andrew Lange (1957-2010)

Science.gov (United States)

Kamionkowski, Marc

2011-12-01

The worlds of physics and astrophysics were stunned to learn on 22 January 2010 that Andrew Lange, the Marvin L. Goldberger Professor of Physics at Caltech, had taken his own life the night before. He had succumbed to the severe depression that he had suffered from for many years, unbeknownst to even his closest colleagues. Lange will perhaps be best remembered as the co-leader of Boomerang, the balloon-borne experiment that provided the first high-angular-resolution map of the cosmic microwave background (CMB). And while this was certainly his most notable achievement, Andrew amassed a record of accomplishment as an instrumentalist, leader, mentor, and communicator that extended much further. Andrew was born in Urbana, Illinois on July 23, 1957, the son of an architect and a librarian, and raised primarily in Connecticut. His family and early friends remember him as a serious and extremely intelligent child and young man. Andrew Lange's lifelong interest in the CMB was nurtured as an undergraduate at Princeton University by David Wilkinson, and he recalled fondly a summer spent working with John Mather at Goddard Space Flight Center. Andrew Lange went to graduate school in physics at Berkeley where he worked in Paul Richards' group. Although his thesis project, the Berkeley-Nagoya rocket experiment, showed an anomalous sub-millimeter excess in the CMB spectrum that was shortly thereafter shown by a later flight of the same rocket and COBE-FIRAS to be incorrect, Lange's talents were recognized by the physics department at Berkeley who appointed him shortly after his PhD (1987) to their faculty. While on the Berkeley faculty, Andrew obtained early detections of the Sunyaev-Zeldovich effect, upper limits to small-angle CMB fluctuations, and important infrared constraints to the interstellar medium. He also led a pioneering instrument operating 300 mK detectors for a small infrared satellite experiment. This early work showed high ambition and daring, and it pioneered

Johann de Lange

African Journals Online (AJOL)

Owner

In hierdie elfde bundel van De Lange bevestig hy sy verdiende en gekanoniseerde posisie in die Afrikaanse dig- kuns, in besonder vanweë 'n volgehoue sig- baarmaking van verhoudinge tussen mens en kosmos; mens en medemens; besit en ver- lies; broosheid/verganklikheid/verwonding teenoor herstel en heelmaking.

T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis.

Science.gov (United States)

Held, Kathrin; Beltrán, Eduardo; Moser, Markus; Hohlfeld, Reinhard; Dornmair, Klaus

2015-09-01

Mucosal-associated invariant T (MAIT) cells are a T-cell subset that expresses a conserved TRAV1-2 (Vα7.2) T-cell receptor (TCR) chain and the surface marker CD161. They are involved in the defence against microbes as they recognise small organic molecules of microbial origin that are presented by the non-classical MHC molecule 1 (MR1). MAIT cells express a semi-restricted TCR α chain with TRAV1-2 preferentially linked to TRAJ33, TRAJ12, or TRAJ20 which pairs with a limited set of β chains. To investigate the TCR repertoire of human CD161(hi)TRAV1-2(+) T cells in depth we analysed the α and β chains of this T-cell subset by next generation sequencing. Concomitantly we analysed 132 paired α and β chains from single cells to assess the αβ pairing preferences. We found that the CD161(hi)TRAV1-2(+) TCR repertoire in addition to the typical MAIT TCRs further contains polyclonal elements reminiscent of classical αβ T cells. Copyright © 2015 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

Rein Lang : liitriiki ei tule / Rein Lang ; interv. Sten Hansson

Index Scriptorium Estoniae

Lang, Rein, 1957-

2003-01-01

Ilmunud ka: Severnoje Poberezhje 16. juuli lk. 2, Lääne Elu 17. juuli lk. 4, Meie Maa 17. juuli lk. 2, Koit 17. juuli lk. 6, Vooremaa 17. juuli lk. 2, Hiiu Leht 22. juuli lk. 2, Nädaline 2. august lk. 4. Intervjuu Euroopa Liidu tulevikukonvendis osalenud Rein Lang'iga EL-i põhiseaduse projektist

Brachman de lange syndrome

Directory of Open Access Journals (Sweden)

Leena Verma

2010-01-01

Full Text Available Brachman de Lange syndrome or Cornelia de Lange syndrome (CdLS is a genetic disorder which can lead to severe developmental anomalies. It affects both the physical and intellectual development of a child. It is characterized by skeletal, craniofacial deformities, gastrointestinal and cardiac malformations. This syndrome is of rare occurrence and affects between 1/10,000 and 1/60,000 neonates. Diagnosis is based on the characteristic phenotype, in particular, a striking facial appearance, prenatal and postnatal growth retardation, various skeletal abnormalities, hypertrichosis, and developmental delay. Here, we present the case of a 13-year-old patient, with micrognathia, delayed eruption, multiple carious teeth, missing teeth and periodontal problems together, which had never been reported before. The father was also found to have the same missing teeth as the girl child.

Seabed sets the pace for Ormen Lange

International Nuclear Information System (INIS)

Knott, T.

2001-01-01

The article describes Norway's Ormen Lange development with its 400 billion cubic metres of gas reserves. Its strategic importance is two-fold: (i) it will provide the infrastructure for Norway to unlock a new offshore region in mid-Norway and (ii) for Europe, it will coincide with an expected shortfall in gas supplies at a time of increasing energy demand. Ormen Lange is expected to be the driver for new gas developments for Norway in terms of production and exports. The Ormen Lange reservoir is 1900m below the seabed where the water depth is 800-1100m. At present, Norsk Hydro (the operator) is considering three main development options for the field's facilities and each is described. The seabed terrain presents some of the most difficult problems the industry has ever tackled

Luftkvalitet langs motorveje

DEFF Research Database (Denmark)

Jensen, S. S.; Løfstrøm, P.; Berkowicz, R.

Denne rapport beskriver måle- og modelresultater. Målekampagnen blev gennemført langs Køge Bugt motorvejen ved Greve for en 3 måneders periode i efteråret 2003, hvor der blev målt NOx (NO og NO2) i forskellige afstande af motorvejen. Der er endvidere opstillet en luftkvalitetsmodel, som beskriver...

Lange »krigsballetter«

DEFF Research Database (Denmark)

Petersen, Hanne

2016-01-01

Artiklen undersøger Den Westfalske Fred (1648) og Tredveårskrigen (den lange krigsballet) i lyset af nutidige langvarige krigsballetter, der foreløbig har karakteriseret det meste af det 21. århundrede. Begge er fragmenterede, brutale, kyniske, og karakteriseret af reseksualiseret voldsanvendelse...

Kaj Ulrik Linderstrøm-Lang (1896-1959).

Science.gov (United States)

Schellman, J A; Schellman, C G

1997-05-01

The Carlsberg Laboratory in Copenhagen has had a long tradition of outstanding science. At the time covered by this discussion, Kjeldahl, Sørensen, and Linderstrøm-Lang had been consecutive directors of the Chemical Laboratory for 83 years. Lang's inspired leadership began in the 1930s with a number of innovations (study of metabolism in single cells, titrations in non-aqueous solvents, relation of proteolysis to structure) but it was not until the early 1950s that Denmark had sufficiently recovered from the war for the laboratory to enter world science again. During World War II, Lang had been active in the Danish resistance movement. After the war, a number of major advances were being made that would revolutionize the field of protein chemistry (Pauling and Corey's H-bonded structures, Sanger's sequencing techniques, chromatography, Watson and Crick structures, modern instrumentation). The time for the new field of the physical biochemistry of proteins had arrived. Lang, with his broad experience, adventurous spirit, and genius for innovation, created an environment that was ideal for the convergence of these disconnected advances into a uniform science. The emphasis was to be on quantitative measurements on proteins in solution with interpretations based on molecular structures. During an all-too-brief period of time, Lang's laboratory attracted a large fraction of those who were destined to be the leaders of the next generation of protein chemists. At this time, the Carlsberg Laboratory was probably the most scientifically exciting environment for a protein chemist. The methods developed at that time-hydrogen exchange, limited proteolysis, optical rotatory dispersion, volume changes accompanying protein reactions, automatic titrations-are still all in common use and many of the visitors to the laboratory in that period and their students are still playing major roles in protein research. Lang's other qualities should not be ignored. He was not only a great

Lange Bramke

International Nuclear Information System (INIS)

Hauhs, M.

1989-01-01

The forested catchment of Lange Bramke In the Harz Mountains (FRG) has been hydrologically monitored since 1948 when it was clear-cut. Today the catchment is covered by a 38-year-old Norway spruce (Picea abies Karst.) stand. Seepage water pathways through the catchment and ion cycling have been investigated in detail during the last 10 years. The results show that seepage water through the root zone is vertical and unsaturated at the catchment slopes. The derived model of seepage water trajectories matches the observed chemical gradients between soil solution, headwater, groundwater, and runoff

Langi retseptid majanduse restartimiseks / Rein Lang

Index Scriptorium Estoniae

Lang, Rein, 1957-

2008-01-01

Justiitsminister Rein Lang selgitab Maksumaksjale majanduse taaskäivitamise ideid, millest oli juttu 15. nov. 2008. aasta Reformierakonna majanduskonverentsil Restart ja Äripäev Onlines (15.11.2008)

Cornelia de Lange Syndrome Foundation

Science.gov (United States)

... Outside Links Privacy & Terms Site Map The Cornelia de Lange Syndrome (CdLS) Foundation is a family support organization that ... research into the causes and manifestations of the syndrome, and help people with a diagnosis of CdLS make informed decisions throughout their lives.

Neuroimaging features of Cornelia de Lange syndrome

Energy Technology Data Exchange (ETDEWEB)

Whitehead, Matthew T. [Department of Radiology, Washington, DC (United States); Nagaraj, Usha D. [Department of Radiology, Washington, DC (United States); Cincinnati Children' s Hospital, Department of Radiology, Cincinnati, OH (United States); Pearl, Phillip L. [Department of Radiology, Washington, DC (United States); Boston Children' s Hospital, Department of Neurology, Boston, MA (United States)

2015-08-15

Cornelia de Lange syndrome is a rare genetic disease characterized by distinctive facial dysmorphia and dwarfism. Multiple organ system involvement is typical. Various central nervous system (CNS) aberrations have been described in the pathology literature; however, the spectrum of neuroimaging manifestations is less well documented. To present neuroimaging findings from a series of eight patients with Cornelia de Lange syndrome. The CT/MR database at a single academic children's hospital was searched for the terms ''Cornelia'', ''Brachmann'' and ''de Lange.'' The search yielded 18 exams from 16 patients. Two non-CNS and six exams without available images were excluded. Ten exams from eight patients were evaluated by a board-certified neuroradiologist. All patients had skull base dysplasia, most with an unusual coronal basioccipital cleft (7/8). All brain MR exams showed microcephaly, volume loss and gyral simplification (5/5). Six patients had an absent massa intermedia. Four patients had small globe anterior segments; three had optic pathway hypoplasia. Basilar artery fenestration was present in two patients; vertebrobasilar hypoplasia was present in one patient. The inner ear vestibules were dysplastic in two patients. One patient had pachymeningeal thickening. Spinal anomalies included scoliosis, segmentation anomalies, endplate irregularities, basilar invagination, foramen magnum stenosis and tethered spinal cord. Typical imaging manifestations of Cornelia de Lange syndrome include skull base dysplasia with coronal clival cleft, cerebral and brainstem volume loss, and gyral simplification. Membranous labyrinth dysplasia, anterior segment and optic pathway hypoplasia, basilar artery fenestration, absent massa intermedia and spinal anomalies may also be present. (orig.)

Neuroimaging features of Cornelia de Lange syndrome

International Nuclear Information System (INIS)

Whitehead, Matthew T.; Nagaraj, Usha D.; Pearl, Phillip L.

2015-01-01

Cornelia de Lange syndrome is a rare genetic disease characterized by distinctive facial dysmorphia and dwarfism. Multiple organ system involvement is typical. Various central nervous system (CNS) aberrations have been described in the pathology literature; however, the spectrum of neuroimaging manifestations is less well documented. To present neuroimaging findings from a series of eight patients with Cornelia de Lange syndrome. The CT/MR database at a single academic children's hospital was searched for the terms ''Cornelia'', ''Brachmann'' and ''de Lange.'' The search yielded 18 exams from 16 patients. Two non-CNS and six exams without available images were excluded. Ten exams from eight patients were evaluated by a board-certified neuroradiologist. All patients had skull base dysplasia, most with an unusual coronal basioccipital cleft (7/8). All brain MR exams showed microcephaly, volume loss and gyral simplification (5/5). Six patients had an absent massa intermedia. Four patients had small globe anterior segments; three had optic pathway hypoplasia. Basilar artery fenestration was present in two patients; vertebrobasilar hypoplasia was present in one patient. The inner ear vestibules were dysplastic in two patients. One patient had pachymeningeal thickening. Spinal anomalies included scoliosis, segmentation anomalies, endplate irregularities, basilar invagination, foramen magnum stenosis and tethered spinal cord. Typical imaging manifestations of Cornelia de Lange syndrome include skull base dysplasia with coronal clival cleft, cerebral and brainstem volume loss, and gyral simplification. Membranous labyrinth dysplasia, anterior segment and optic pathway hypoplasia, basilar artery fenestration, absent massa intermedia and spinal anomalies may also be present. (orig.)

Ormen Lange subsea development strategy and execution

Energy Technology Data Exchange (ETDEWEB)

Hogmoen, K. [Norsk Hydro, Oslo (Norway)

2007-07-01

Ormen Lange is the largest natural gas field in development on the Norwegian continental shelf. This paper discussed Norsk Hydro's Ormen Lange development strategy and execution. Several illustrations of the Ormen Lange project were presented, including the field layout and the main challenges of working in deep water. Other challenges involve environmental conditions; long distance control; and hydrate prevention. Several components of the project were presented, including the xmas tree handling system; choke module; control system; large bore tie-in system; in-line tee system; and free spans in pipeline design. Other topics that were presented and illustrated included the feasibility of pipeline design; design optimization with installation contractors; design optimization between intervention methods; positioning; dredging with spiders; excavation with jetprops; ploughing; rock installation; and trenching. The installation of thirty inch pipelines and umbilical lines in shallow and deep water were also discussed and illustrated. The presentation concluded with a discussion of lessons learned subsea. These included early definition of operational requirements; close monitoring of interface work between contractors; professional change management; and thorough testing onshore prior to installation. Securing vessel capacity and timely start-up were among the lessons learned for marine operations. figs.

Half-Forgotten Personalities of Economic Thought – O. R. Lange

Directory of Open Access Journals (Sweden)

Pavel Sirůček

2017-03-01

Full Text Available O. R. Lange, a Polish economist, statistician, econometrician, sociologist, politician and diplomat was classified as a reformist Marxist. He became famous for studies on planning and socialist economies. Lange demonstrates and proves the possibility of the existence of an effective socialist system. He also analyzed capitalist economy, e.g., the issue of cyclical fluctuations and unemployment.

Eestlastest tippjuhid kerge südamega võõrsile leiba teenima ei lähe / Mait Raava, Indrek Neivelt, Maive Rute ; interv. Tuuliki Kasonen-Lins

Index Scriptorium Estoniae

Raava, Mait

2006-01-01

Pro Konsultatsioonide juhtimiskonsultant Mait Raava, Bank Saint Petersburgi nõukogu esimees Indrek Neivelt, Euroopa Komisjoni innovatsiooni ja väikeettevõtluse üksuse direktor Maive Rute vastavad küsimustele, mis puudutavad Eesti juhtide mainet ning töötamist välisriikides

Tähed disainiöös / Mait Summatavet, Risto Räägel, Per Mollerup...[jt.] ; interv. Karin Paulus

Index Scriptorium Estoniae

2007-01-01

Disainiöö raames avati Arhitektuuri- ja Disainigaleriis näitus "Kokkupandavad asjad" ning kuulutati välja konkursi võitjad. Peapreemia võitis läti disaineri Elina Bushmane kokkupandav teelaud, teise koha Jaana Päeva tekstiilist kott, kolmanda koha Ingrem Floreni käekott. Ära märgiti Veiko Liisi kilepiima vutlar. Disainiöö üritustest ning konkursitöödest räägivad Mait Summatavet, Per Mollerup, Simo Heikkilä, Risto Räägel

The Brachmann-De Lange Syndrome

African Journals Online (AJOL)

1974-05-04

May 4, 1974 ... Two patients with the Brachmann-De Lange syndrome are described. The condition is not uncommon and is ... infection with difficulty in sucking and the child did not take feeds well during the whole of the first ... the right fifth finger was due to hypoplasia of the middle phalanx. The patient remained severely ...

Mechanisms and processes of stratal disruption and mixing in the development of mélanges and broken formations: Redefining and classifying mélanges

Science.gov (United States)

Festa, A.; Dilek, Y.; Pini, G. A.; Codegone, G.; Ogata, K.

2012-09-01

The terms mélange and broken formation have been used in different ways in the literature. The lack of agreement on their definition often leads to confusion and misinterpretations. An evaluation of the various uses of these terms allows us to consider several types of chaotic rock bodies originated by tectonic, sedimentary and diapiric processes in different tectonic settings. Our review of stratal disruption and mixing processes shows that there exists a continuum of deformation structures and processes in the generation of mélanges and broken formations. This continuum is directly controlled by the increase of the degree of consolidation with burial. In tectonically active environments, at the shallow structural levels, the occurrence of poorly consolidated sediments favors gravitational deformation. At deeper structural levels, the deformation related to tectonic forces becomes gradually more significant with depth. Sedimentary (and diapiric) mélanges and broken formations represent the products of punctuated stratal disruption mechanisms recording the instantaneous physical conditions in the geological environment at the time of their formation. The different kinematics, the composition and lithification degree of sediments, the geometry and morphology of the basins, and the mode of failure propagation control the transition between different types of mass-transported chaotic bodies, the style of stratal disruption, and the amount of rock mixing. Tectonically broken formations and mélanges record a continuum of deformation that occurs through time and different degrees of lithification during a progressive increase of the degree of consolidation and of the diagenetic and metamorphic mineral transformation. Systematic documentation of the mechanisms and processes of the formation of different broken formations and mélanges and their interplay in time and space are highly important to increase the understanding of the evolutionary history of accretionary

Genetics Home Reference: Jervell and Lange-Nielsen syndrome

Science.gov (United States)

... Home Edition for Patients and Caregivers: Long QT Syndrome and Torsades de Pointes Ventricular Tachycardia Orphanet: Familial long QT syndrome Orphanet: Jervell and Lange-Nielsen syndrome Patient Support ...

Unusual association of non-anaplastic Wilms tumor and Cornelia de Lange syndrome: case report.

Science.gov (United States)

Santoro, Claudia; Apicella, Andrea; Casale, Fiorina; La Manna, Angela; Di Martino, Martina; Di Pinto, Daniela; Indolfi, Cristiana; Perrotta, Silverio

2016-06-13

Cornelia de Lange syndrome is the prototype for cohesinopathy disorders, which are characterized by defects in chromosome segregation. Kidney malformations, including nephrogenic rests, are common in Cornelia de Lange syndrome. Only one post-mortem case report has described an association between Wilms tumor and Cornelia de Lange syndrome. Here, we describe the first case of a living child with both diseases. Non-anaplastic triphasic nephroblastoma was diagnosed in a patient carrying a not yet reported mutation in NIPBL (c.4920 G > A). The patient had the typical facial appearance and intellectual disability associated with Cornelia de Lange syndrome in absence of limb involvement. The child's kidneys were examined by ultrasound at 2 years of age to exclude kidney abnormalities associated with the syndrome. She underwent pre-operative chemotherapy and nephrectomy. Seven months later she was healthy and without residual detectable disease. The previous report of such co-occurrence, together with our report and previous reports of nephrogenic rests, led us to wonder if there may be any causal relationship between these two rare entities. The wingless/integrated (Wnt) pathway, which is implicated in kidney development, is constitutively activated in approximately 15-20 % of all non-anaplastic Wilms tumors. Interestingly, the Wnt pathway was recently found to be perturbed in a zebrafish model of Cornelia de Lange syndrome. Mutations in cohesin complex genes and regulators have also been identified in several types of cancers. On the other hand, there is no clear evidence of an increased risk of cancer in Cornelia de Lange syndrome, and no other similar cases have been published since the fist one reported by Cohen, and this prompts to think Wilms tumor and Cornelia de Lange syndrome occurred together in our patient by chance.

Unusual association of non-anaplastic Wilms tumor and Cornelia de Lange syndrome: case report

International Nuclear Information System (INIS)

Santoro, Claudia; Apicella, Andrea; Casale, Fiorina; La Manna, Angela; Di Martino, Martina; Di Pinto, Daniela; Indolfi, Cristiana; Perrotta, Silverio

2016-01-01

Cornelia de Lange syndrome is the prototype for cohesinopathy disorders, which are characterized by defects in chromosome segregation. Kidney malformations, including nephrogenic rests, are common in Cornelia de Lange syndrome. Only one post-mortem case report has described an association between Wilms tumor and Cornelia de Lange syndrome. Here, we describe the first case of a living child with both diseases. Non-anaplastic triphasic nephroblastoma was diagnosed in a patient carrying a not yet reported mutation in NIPBL (c.4920 G > A). The patient had the typical facial appearance and intellectual disability associated with Cornelia de Lange syndrome in absence of limb involvement. The child’s kidneys were examined by ultrasound at 2 years of age to exclude kidney abnormalities associated with the syndrome. She underwent pre-operative chemotherapy and nephrectomy. Seven months later she was healthy and without residual detectable disease. The previous report of such co-occurrence, together with our report and previous reports of nephrogenic rests, led us to wonder if there may be any causal relationship between these two rare entities. The wingless/integrated (Wnt) pathway, which is implicated in kidney development, is constitutively activated in approximately 15–20 % of all non-anaplastic Wilms tumors. Interestingly, the Wnt pathway was recently found to be perturbed in a zebrafish model of Cornelia de Lange syndrome. Mutations in cohesin complex genes and regulators have also been identified in several types of cancers. On the other hand, there is no clear evidence of an increased risk of cancer in Cornelia de Lange syndrome, and no other similar cases have been published since the fist one reported by Cohen, and this prompts to think Wilms tumor and Cornelia de Lange syndrome occurred together in our patient by chance

De Juan Goytisolo à Monique Lange, de Monique Lange à Juan Goytisolo : une "intertextualité conjugale"

Directory of Open Access Journals (Sweden)

Emmanuel Le Vagueresse

2006-09-01

Full Text Available Juan Goytisolo (né en 1931, écrivain espagnol, et Monique Lange (1926-1996, écrivain français, ont produit chacun une œuvre à forte résonance autobiographique, sous couvert de fiction, et qui crée un effet très particulier d’inter­textualité par le simple fait qu’ils étaient, dans la vie, mari et femme... D’où ce titre « d’intertextualité conjugale », car ces récits auto-fictionnels croisés de relations communes s’enri­chissent particulièrement du regard critique et lucide de la romancière sur les obsessions personnelles de son écrivain de mari, les décryptant par le biais de personnages « inventés » qui, non seulement renseignent sur un destin littéraire partagé, mais encore et surtout, dans une configuration rare de double écriture, permettent chez Lange de lire différemment les lignes souvent floues (sur la sexualité, les parias, le monde arabe de l’écrivain espagnol bien connu, et même de démystifier ses discours d’Espagnol marginal.

Geen recht de moed te verliezen. Leven en werken van dr. H.M. de Lange (1919-2001)

NARCIS (Netherlands)

Witte-Rang, M.E.

2008-01-01

This study deals with the contribution of the Dutch economist Dr. H.M. de Lange to the ecumenical debate on social-ethics. To this end, the first part gives a description of the work of De Lange. Through the individual De Lange the study provides an insight in the worldwide ecumenical movement and

Cornelia de Lange Syndrome: Evolution of the Phenotype

Science.gov (United States)

Passarge, Eberhard; And Others

1971-01-01

The medical case history of a 2-year-old girl who developed, during the second year of life, the classical phenotype (typical appearance) indicative of the deLange syndrome, with both mental and physical impairment. (KW)

Using a {sigma}-coordinate numerical ocean model for simulating the circulation at Ormen Lange

Energy Technology Data Exchange (ETDEWEB)

Eliassen, Inge K.; Berntsen, Jarle

2000-01-01

This report describes a numerical model for the simulation of circulation at the Ormen Lange oil field. The model uses a topography following vertical coordinate and time split integration procedure. The model is implemented for a 28 km x 46 km area at Ormen Lange. The equations are given in detail and numerical experiments are discussed. The numerical studies investigate how the flow specified at open boundaries surrounding the Ormen Lange area may be interpolated into the interior domain taking into account the conservation laws that are believed to determine the flow and the local topography.

Self-Injury in the De Lange Syndrome.

Science.gov (United States)

Singh, N. N.; Pulman, Ruth M.

1979-01-01

Psychological treatment techniques for the control of self-injury in a 13-year-old male with de Lange syndrome (a rare disorder characterized by retarded mental and physical development) are presented. Techniques, which included mild punishment, time out, and differential reinforcement, produced a clinically significant control of self-injurious…

The Association Between Environmental Events and Self-Injurious Behaviour in Cornelia de Lange Syndrome

Science.gov (United States)

Moss, J.; Oliver, C.; Hall, S.; Arron, K.; Sloneem, J.; Petty, J.

2005-01-01

There has been limited empirical research into the environmental causes of self-injury in Cornelia de Lange syndrome. The present study examined the variability of self-injurious behaviour in Cornelia de Lange syndrome across environmental setting events. Additionally, the association between setting events and more specific environmental events…

Prevalence of Autism Spectrum Phenomenology in Cornelia de Lange and Cri du Chat Syndromes

Science.gov (United States)

Moss, Joanna F.; Oliver, Chris; Berg, Katy; Kaur, Gurmeash; Jephcott, Lesley; Cornish, Kim

2008-01-01

Autism spectrum disorder characteristics have not been evaluated in Cornelia de Lange and Cri du Chat syndromes using robust assessments. The Autism Diagnostic Observation Schedule and Social Communication Questionnaire were administered to 34 participants with Cornelia de Lange syndrome and a comparison group of 23 participants with Cri du Chat…

Kortlægning af luftkvalitet langs motor- og landeveje i Danmark

DEFF Research Database (Denmark)

Jensen, Steen Solvang; Im, Ulas; Ketzel, Matthias

2016-01-01

Denne artikel beskriver resultaterne af en kortlægning af luftkvaliteten langs motor- og landeveje i hele Danmark. Det er første gang, at der skabes et nationalt datasæt af modellerede luftkvalitetsdata langs hele statsvejnettet. Beregningerne er gennemført for årsmiddelkoncentrationer i 2012 af ...... sundheds-relaterede stoffer NO2, PM2.5 og PM10. Kortlægningen er gennemført med OML-Highway luftkvalitets-modellen, og anvendte metoder og datagrundlag er beskrevet. Endvidere er beregningerne sammenholdt med tidligere gennemførte målinger og beregninger....

A mélange of subduction temperatures: Evidence from Zr-in-rutile thermometry for strengthening of the subduction interface

Science.gov (United States)

Penniston-Dorland, Sarah C.; Kohn, Matthew J.; Piccoli, Philip M.

2018-01-01

The Catalina Schist contains a spectacular, km-scale amphibolite facies mélange zone, thought to be part of a Cretaceous convergent margin plate interface. In this setting, blocks ranging from centimeters up to ≥100 m in diameter are surrounded by finer-grained matrix that is derived from the blocks. Blocks throughout the mélange represent a diversity of protoliths derived from basalts, cherts and other sediments, and hydrated mantle, but all contain assemblages consistent with upper amphibolite-facies conditions, suggesting a relatively restricted range of depths and temperatures over which material within the mélange was metamorphosed. This apparent uniformity of metamorphic grade contrasts with other mélanges, such as the Franciscan Complex, where coexisting rocks with highly variable peak metamorphic grade suggest extensive mixing of materials along the subduction interface. This mixing has been ascribed to flow of material within relatively low viscosity matrix. The Zr content of rutile in samples from across the amphibolite facies mélange of the Catalina Schist was measured to determine peak metamorphic temperatures, identify whether these temperatures were different among blocks, and whether the spatial distribution of temperatures throughout the mélange was systematic or random. Resolvably different Zr contents, between 290 and 720 (±10-40) ppm, are found among the blocks, corresponding to different peak metamorphic temperatures of 650 to 730 (±2-16) °C at an assumed pressure of 1 GPa. These results are broadly consistent with previous thermobarometric estimates. No systematic distribution of temperatures was found, however. Like other mélange zones, material flow within the Catalina Schist mélange was likely chaotic, but appears to have occurred on a more restricted scale compared to some other localities. Progressive metamorphism of mélange matrix is expected to produce rheologically stiffer matrix minerals (such as amphiboles and pyroxenes

Unpredictable drug reaction in a child with Cornelia de Lange syndrome.

Science.gov (United States)

Stevic, Marija; Milojevic, Irina; Bokun, Zlatko; Simic, Dusica

2015-02-01

Preoperative use of midazolam sedation is mandatory during induction of anesthesia in noncooperative and hyperactive children to prevent possible obstacles. Unusual drug reactions rarely occur in patients undergoing anesthesia or in intensive care unit. This report describes an unpredictable drug reaction after a routine midazolam premedication in a patient with no history of allergy. There has been no literature data yet to show that midazolam can provoke respiratory problems in patients with Cornelia de Lange Syndrome. In our opinion midazolam should be avoided in patients with Cornelia de Lange Syndrome, which we enforced after first unpredictable reaction.

A Boy with a Mild Case of Cornelia de Lange Syndrome with Above Average Intelligence.

Science.gov (United States)

Lacassie, Yves; Bobadilla, Olga; Cambias, Ron D., Jr.

1997-01-01

Describes the characteristics of an 11-year-old boy who represents the only documented case of an individual with Cornelia de Lange syndrome who also has above average cognitive functioning. Major diagnostic criteria for de Lange syndrome and comparisons with other severe and mild cases are discussed. (Author/CR)

Descriptive epidemiology of Cornelia de Lange syndrome in Europe

DEFF Research Database (Denmark)

Barisic, Ingeborg; Tokic, Visnja; Loane, Maria

2008-01-01

Cornelia de Lange syndrome (CdLS) is a multiple congenital anomaly/mental retardation syndrome consisting of characteristic dysmorphic features, microcephaly, hypertrichosis, upper limb defects, growth retardation, developmental delay, and a variety of associated malformations. We present...

[Cornelia de Lange Syndrome and multiple hormonal deficiency, an unusual association. Clinical case].

Science.gov (United States)

Mora-Bautista, Víctor M; Mendoza-Rojas, Víctor; Contreras-García, Gustavo A

2017-06-01

Cornelia de Lange syndrome is a genetic disease characterized by distinctive facial features, failure to thrive, microcephaly and several malformations associated. Its main endocrinological features are anomalies of the genitalia. We present a 13-year-old boy, who suffered from complicated aspiration pneumonia and showed Cornelia de Lange syndrome phenotype, with global developmental delay, suction-swallowing abnormalities, short stature and abnormal genitalia associated. His bone age was delayed, so he underwent full endocrinological panel. Central hypothyroidism, growth hormone deficiency and low luteinizing hormone-follicle-stimulating hormone levels were observed and multiple pituitary hormone deficiencies diagnosis was made. Basal cortisol, adrenocorticotropic hormone and prolactin levels were normal. He received thyroid hormonal substitution. Multiple pituitary hormone deficiencies are an unusual feature of De Lange syndrome. We suggest evaluating all different endocrine axes in these patients. Sociedad Argentina de Pediatría.

Blogging in the Target Language: Review of the “Lang-8” Online Community

Directory of Open Access Journals (Sweden)

Judith Bündgens-Kosten

2011-06-01

Full Text Available Progress in language learning can be framed as the development of skills in four domains: reading, speaking, writing, and listening. While material to improve reading and listening skills is fairly easy to find, practicing productive skills outside the formal classroom can be more difficult. This is a review of language learning community, Lang-8 (www.lang-8.com.

Environmental Survey at Ormen Lange, June 2009

Energy Technology Data Exchange (ETDEWEB)

Mannvik, Hans-Petter; Wasbotten, Ingar Halvorsen; Cochrane, Sabine

2010-07-01

An environmental monitoring survey was carried out at Ormen Lange in Region V on behalf of Norske Shell. The samples were collected at 19 stations by use of a 0.25 m{sub 2} box corer and carried out in connection with the field work in Region VI. The station depths varied between 823 and 925 m. The sediments at Ormen Lange are classified as silt with a high amount of pelite (> 90 %) and TOM (> 9 %). The amount of pelite is higher than that found in the baseline survey in 2004 at all stations. Whether this is a result of changes in sediment composition or a difference in analytical methods used is not known. With the exception of station OL-01 and OL-09, where a small increase has occurred, the amount of TOM has decreased at the stations since 2004. The concentrations of hydrocarbons and metals in the sediments at Template D, can be regarded as the natural background level for these parameters. The average amount of THC in the sediments around Template D is 11.7 +- 1.8 mg/kg in this base line survey. The average level of THC at template A and B was at the same level in the base line survey in 2004, 9.7 +- 0.6 mg/kg. In the present survey the average amount of THC in the sediments at Template A and B has increased to 17.0 +- 3.9 mg/kg. 11 of 14 stations at Template A and B have slightly elevated levels of barium and zinc in the sediments and sediments at three stations are elevated with mercury. In the present survey the mollusks dominates the fauna at Ormen Lange. The number of individuals at the stations (0.4 m{sub 2}) is high (1553 - 2833), while the number of taxa is relatively low (51 - 73), resulting in a very low diversity (H' 2.4 - 3.3). This is due to the over dominance by two mussels (Thyasira minuta and T. equalis) at all stations. However, the dominant species registered are known to be abundant in sediment with high amount of pelite and organic material. Due to the different sampling strategy and area, a direct comparison with the baseline survey is

Social Anxiety in Cornelia de Lange Syndrome

Science.gov (United States)

Richards, Caroline; Moss, Jo; O'Farrell, Laura; Kaur, Gurmeash; Oliver, Chris

2009-01-01

In this study we assessed the behavioral presentation of social anxiety in Cornelia de Lange syndrome (CdLS) using a contrast group of Cri du Chat syndrome (CdCS). Behaviors indicative of social anxiety were recorded in twelve children with CdLS (mean age = 11.00; SD = 5.15) and twelve children with CdCS (8.20; SD = 2.86) during social…

Ants Orasest ja Anne Lange monograafiast / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

2005-01-01

Arvustus: Oras, Ants. Luulekool. I, Apoloogia / koostajad Hando Runnel ja Jaak Rähesoo. Tartu : Ilmamaa, 2003 ; Oras, Ants. Luulekool II, Meistriklass. Tartu : Ilmamaa, 2004 ; Lange, Anne. Ants Oras : [kirjandusteadlane, -kriitik ja tõlkija (1900-1982)]. Tartu : Ilmamaa, 2004

Friedrich Albert Lange on neo-Kantianism, socialist Darwinism, and a psychology without a soul.

Science.gov (United States)

Teo, Thomas

2002-01-01

Friedrich Albert Lange was a German philosopher, political theorist, educator, and psychologist who outlined an objective psychology in the 1860s. This article shows how some of the most important worldviews of the nineteenth century (Kantianism, Marxism, and Darwinism) were combined creatively in his thought system. He was crucial in the development of neo-Kantianism and incorporated psycho-physiological research on sensation and perception in order to defend Kant's epistemological idealism. Based on a critique of phrenology and philosophical psychology of his time, Lange developed a program of a psychology without a soul. He suggested that only those phenomena that can be observed and controlled should be studied, that psychology should focus on actions and speech, and that for each psychological event the corresponding physical or physiological processes should be identified. Lange opposed introspection and subjective accounts and promoted experiments and statistics. He also promoted Darwinism for psychology while developing a socialist progressive-democratic reading of Darwin in his social theory. The implications of socialist Darwinism on Lange's conceptualization of race are discussed and his prominence in nineteenth century philosophy and psychology is summarized. Copyright 2002 Wiley Periodicals, Inc.

Soot concentrations along busy inland waterways in the Netherlands; Roetconcentraties langs drukke binnenvaarwegen in Nederland

Energy Technology Data Exchange (ETDEWEB)

Keuken, M.; Jonkers, S.; Moerman, M. [TNO Built Environment and Geosciences, Delft (Netherlands); Hoek, G. [Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht (Netherlands)

2013-08-15

Exploratory research by TNO and IRAS shows that residents in the Netherlands are exposed to soot concentrations along busy inland waterways similar to living along a busy highway [Dutch] Verkennend onderzoek van TNO en IRAS laat zien dat bewoners langs drukke binnenvaarwegen worden blootgesteld aan roetconcentraties vergelijkbaar met wonen langs een drukke snelweg.

Mechanisms and processes of stratal disruption and mixing in the development of m??langes and broken formations: Redefining and classifying m??langes

NARCIS (Netherlands)

Festa, A.; Dilek, Yildirim; Pini, Gian Andrea; Codegone, Giulia; Ogata, K.

2012-01-01

The terms m??lange and broken formation have been used in different ways in the literature. The lack of agreement on their definition often leads to confusion and misinterpretations. An evaluation of the various uses of these terms allows us to consider several types of chaotic rock bodies

Delineating the Profile of Autism Spectrum Disorder Characteristics in Cornelia de Lange and Fragile X Syndromes

Science.gov (United States)

Moss, Joanna; Oliver, Chris; Nelson, Lisa; Richards, Caroline; Hall, Scott

2013-01-01

An atypical presentation of autism spectrum disorder is noted in Cornelia de Lange and Fragile X syndromes, but there are few detailed empirical descriptions. Participants in this study were individuals with Cornelia de Lange syndrome (n = 130, M age = 17.19), Fragile X syndrome (n = 182, M age = 16.94), and autism spectrum disorder (n = 142, M…

Psychological Well-Being in Parents of Children with Angelman, Cornelia de Lange and Cri du Chat Syndromes

Science.gov (United States)

Griffith, G. M.; Hastings, R. P.; Oliver, C.; Howlin, P.; Moss, J.; Petty, J.; Tunnicliffe, P.

2011-01-01

Background: The current study focuses on mothers and fathers of children with three rare genetic syndromes that are relatively unexplored in terms of family experience: Angelman syndrome, Cornelia de Lange syndrome and Cri du Chat syndrome. Method: Parents of children with Angelman syndrome (n = 15), Cornelia de Lange syndrome (n = 16) and Cri du…

Zamanın Bir Başlangıcı Olmalı mıdır?

Directory of Open Access Journals (Sweden)

Zikri Yavuz

2015-12-01

Full Text Available Bu makalede, zamanın bir başlangıcı olup olmadığını tartışacağım. Büyük patlama modeline göre, evrenimiz sonsuz bir şekilde geçmişe sahip değildir. Bu, muhtemelen modern kozmolojinin en görkemli keşiflerinden birisidir. Buna rağmen bazı filozoflar zamanın zorunlu olarak bir başlangıcının olmadığını iddia etmektedirler. Büyük patlamanın âlemin zamansal bir başlangıcı olduğu görüşünü desteklediğini ileri süreceğim. Aynı zamanda zamanın başlangıcı olmadığına dair a priori argümanların da başarılı olmadığını göstermeyi deneyeceğim.

Cornelia de-Lange syndrome - A case report

Directory of Open Access Journals (Sweden)

Charvi Chawla

2018-01-01

Full Text Available Cornelia de-Lange syndrome (CdLS is a rare multisystem developmental disorder characterized by psychomotor retardation and delayed growth associated with a series of malformations, including facial dysmorphia, upper-extremity malformations, hirsutism, cardiac defects, and gastrointestinal abnormalities. There is no definitive biochemical or chromosomal marker for the prenatal diagnosis of syndrome so it is important for the clinician to know etiopathological aspects and characteristic features to provide health care and help improve the quality of life of affected individuals.

Holocene reef building on eastern St. Croix, US Virgin Islands: Lang Bank revisited

Science.gov (United States)

Hubbard, D. K.; Gill, I. P.; Burke, R. B.

2013-09-01

New core and seismic data suggest that widespread reef building started on Lang Bank by 8,900 CalBP and was dominated by Acropora palmata for the next three millennia. Accretion rates averaged 5.81 m ky-1, a rate that was sufficient for reefs to keep pace with rising sea level on the bank throughout their history. Seismic data show a deep platform interior that was flooded well in advance of reef building along the elevated rim. As a result, those reefs were buffered from sediment stress by their higher positions and active water flow to the west. A. palmata disappeared from the shallow margin by 6,350 yr ago, and reef building on Lang Bank largely ceased by 5,035 CalBP. The reasons for these dramatic events are unclear. Water depth over the reefs was generally shallower than when they started to build, and sea level was slowing dramatically. The new data described here show that reefs flourished on Lang Bank throughout the hiatus suggested by earlier studies (10-7 kyrs BP), and the ultimate demise of shelf-edge reefs is clearly not associated with either poor water quality or sudden sea-level rise. In addition, accretion rates from eastern St. Croix and throughout the Caribbean were well below the high values (≥10 m ky-1) that have been widely assumed. These data collectively argue against models that require extreme environmental or oceanographic phenomena to drown reefs on Lang Bank where reef building was too fast to be outpaced by Holocene sea-level rise. This also bears on more generalized Caribbean models that depend on the presumed reef history on eastern St. Croix.

Musical Me'lange and Lyrical Universalism in the Works of Carlos ...

African Journals Online (AJOL)

The paper, ab initio, accepts that music is a veritable vehicle of globalization ... a musical mélange in which people from various cultures could find something to ... a result of the diverse global elements in his works and the resultant universal ...

Characteristics of Autism Spectrum Disorder in Cornelia de Lange Syndrome

Science.gov (United States)

Moss, Jo; Howlin, Patricia; Magiati, Iliana; Oliver, Chris

2012-01-01

Background: The prevalence of autism spectrum disorder (ASD) symptomatology is comparatively high in Cornelia de Lange syndrome (CdLS). However, the profile and developmental trajectories of these ASD characteristics are potentially different to those observed in individuals with idiopathic ASD. In this study we examine the ASD profile in CdLS in…

Carbon Markets and REDD in South-East Asia: An Interview with Chris Lang from REDD-Monitor

Directory of Open Access Journals (Sweden)

Oliver Pye

2012-01-01

Full Text Available Chris Lang is a climate justice activist and currently runs REDD-Monitor, a website that follows projects and developments around REDD (www.redd-monitor.org. The acronym REDD refers to Re- ducing Emissions from Deforestation and Forest Degradation and is a UN programme that aims to offer incentives for countries in the Global South to reduce emissions from deforestation by creating financial values for the forest carbon stocks. In this interview, Lang talks about structural shortcomings of REDD and the danger of carbon cowboys, provides an insight in the 1 billion dollar agreement between Norway and Indonesia, and discusses the relation between REDD and indigenous peoples’ rights. ----- Chris Lang ist Klimaaktivist und betreibt derzeit die Webseite REDD-Monitor, die Projekte und En- twicklungen rund um REDD verfolgt (www.redd-monitor.org. Die Abkürzung REDD bezieht sich auf das UN-Programm Reducing Emissions from Deforestation and Forest Degradation, das darauf abzielt, Anreize für Länder des globalen Südens zu schaffen, ihre Emissionen aus Abholzung durch finanzielle Werte für den Kohlenstoffgehalt der Wälder zu reduzieren. In diesem Interview spricht Lang über strukturelle Schwächen von REDD und der Gefahr durch carbon cowboys. Er gibt einen Einblick in das 1-Milliarde-Dollar Abkommen zwischen Norwegen und Indonesien und diskutiert die Beziehung zwischen REDD und den Rechten indigener Völker.

Discovery of the early Jurassic Gajia mélange in the Bangong-Nujiang suture zone: Southward subduction of the Bangong-Nujiang Ocean?

Science.gov (United States)

Lai, Wen; Hu, Xiumian; Zhu, Dicheng; An, Wei; Ma, Anlin

2017-06-01

Mélange records a series of geological processes associated with oceanic subduction and continental collision. This paper reports for the first time the presence of Early Jurassic mélange from NW Nagqu in the southern margin of the Bangong-Nujiang suture zone, termed as the Gajia mélange. It shows typically blocks-in-matrix structure with matrix of black shale and siliceous mudstone, and several centimeters to several meters sized blocks of sandstone, silicalite, limestone and basalt. The sandstone blocks consist of homologous sandstone and two types of exotic sandstone, with different modal compositions. The Group 1 of exotic sandstone blocks consists of mainly of feldspar and quartz, whereas the Group 2 is rich in volcanic detritus. The Group 3 of homologous sandstone blocks is rich in feldspar and volcanic detritus with rare occurrence of quartz. U-Pb age data and in situ Hf isotopic compositions of detrital zircons from sandstone blocks are similar to those from the Lhasa terrane, suggesting that the sandstone blocks in the Gajia mélange most probably came from the Lhasa terrane. The YC1σ(2+) age of homologous sandstone blocks is 177 ± 2.4 Ma, suggesting an Early Jurassic depositional age for the sandstones within the Gajia mélange. The Gajia mélange likely records the southward subduction of the Bangong-Nujiang Ocean during the Early Jurassic.

Doktoritööd : [2007, Anne Lange jt.

Index Scriptorium Estoniae

2007-01-01

20. veebr. kaitseb Anne Lange doktoritööd "The poetics of translation of Ants Oras". 19. jaan. kaitses Tuuli Oder doktoritööd "The model of contemporary professional foreign language teacher". 16. jaan. kaitses Tiit Maran doktoritööd "Conservation biology of the European mink, Mustela lutreola (Linnaeus 1761): decline and causes of extinction". 12. jaan. kaitses Maris Saagpakk doktoritööd "Deutschbaltische Autobiographien als Dokumente des Zeit- und Selbstempfindens: vom Ende des 19. Jh. bis zur Umsiedlung 1939"

Disfagia orofaríngea em crianças com síndrome Cornélia de Lange Oropharyngeal dysphagia in children with Cornelia de Lange syndrome

Directory of Open Access Journals (Sweden)

Priscila Martins Foroni

2010-10-01

Full Text Available OBJETIVO: descrever os achados das fases oral e faríngea da deglutição, bem como os aspectos sensório-motores orofaciais relevantes em crianças com a síndrome Cornélia de Lange. MÉTODOS: trata-se de relato de caso, retrospectivo. Realizou-se análise descritiva de quatro protocolos de avaliação fonoaudiológica da deglutição da rotina do Serviço de Fonoaudiologia de crianças com a síndrome Cornélia de Lange, de ambos os sexos, com faixa etária entre 1:2 e 9:6 anos, encaminhadas para avaliação clínica e videofluoroscópica da deglutição em um hospital público universitário. Analisou-se os aspectos das fases oral e faríngea da deglutição por meio da avaliação clínica do sistema sensório-motor orofacial, avaliação clínica funcional e videofluoroscópica. RESULTADOS: As alterações do sistema sensório-motor orofacial mais encontradas foram a hipersensibilidade e a hipertonia muscular da região orofacial. Na fase oral da deglutição, dentre as alterações observadas, destacaram-se a presença de vedamento labial ineficiente, escape oral anterior do bolo alimentar, inadequada formação/organização do bolo e ejeção oral deficiente. Na fase faríngea, observou-se ausculta cervical alterada, refluxo nasal, excursão hiolaríngea reduzida, presença de resíduo em trânsito faríngeo após a deglutição, penetração laríngea e aspiração laringotraqueal. A disfagia orofaríngea foi encontrada em todas as crianças. CONCLUSÃO: Os achados encontrados apontaram alterações nos aspectos sensório-motores orofaciais e comprometimento na biomecânica da deglutição. As importantes alterações na deglutição evidenciadas nos casos descritos podem corresponder a manifestações típicas da síndrome Cornélia de Lange.PURPOSE: to describe the findings for the oral and pharyngeal phases of swallowing, as well as the relevant orofacial sensorimotor aspects for children with Cornelia de Lange syndrome. METHODS

Age and microfacies of oceanic Upper Triassic radiolarite components from the Middle Jurassic ophiolitic mélange in the Zlatibor Mountains (Inner Dinarides, Serbia and their provenance

Directory of Open Access Journals (Sweden)

Gawlick Hans-Jürgen

2017-08-01

Full Text Available Oceanic radiolarite components from the Middle Jurassic ophiolitic mélange between Trnava and Rožanstvo in the Zlatibor Mountains (Dinaridic Ophiolite Belt west of the Drina–Ivanjica unit yield Late Triassic radiolarian ages. The microfacies characteristics of the radiolarites show pure ribbon radiolarites without crinoids or thin-shelled bivalves. Beside their age and the preservation of the radiolarians this points to a deposition of the radiolarites on top of the oceanic crust of the Neo-Tethys, which started to open in the Late Anisian. South of the study area the ophiolitic mélange (Gostilje–Ljubiš–Visoka–Radoševo mélange contains a mixture of blocks of 1 oceanic crust, 2 Middle and Upper Triassic ribbon radiolarites, and 3 open marine limestones from the continental slope. On the basis of this composition we can conclude that the Upper Triassic radiolarite clasts derive either from 1 the younger parts of the sedimentary succession above the oceanic crust near the continental slope or, more convincingly 2 the sedimentary cover of ophiolites in a higher nappe position, because Upper Triassic ribbon radiolarites are only expected in more distal oceanic areas. The ophiolitic mélange in the study area overlies different carbonate blocks of an underlying carbonate-clastic mélange (Sirogojno mélange. We date and describe three localities with different Upper Triassic radiolarite clasts in a mélange, which occurs A on top of Upper Triassic fore-reef to reefal limestones (Dachstein reef, B between an Upper Triassic reefal limestone block and a Lower Carnian reef limestone (Wetterstein reef, and C in fissures of an Upper Triassic lagoonal to back-reef limestone (Dachstein lagoon. The sedimentary features point to a sedimentary and not to a tectonic emplacement of the ophiolitic mélange (= sedimentary mélange filling the rough topography of the topmost carbonate-clastic mélange below. The block spectrum of the underlying and

Age and microfacies of oceanic Upper Triassic radiolarite components from the Middle Jurassic ophiolitic mélange in the Zlatibor Mountains (Inner Dinarides, Serbia) and their provenance

Science.gov (United States)

Gawlick, Hans-Jürgen; Djerić, Nevenka; Missoni, Sigrid; Bragin, Nikita Yu.; Lein, Richard; Sudar, Milan; Jovanović, Divna

2017-08-01

Oceanic radiolarite components from the Middle Jurassic ophiolitic mélange between Trnava and Rožanstvo in the Zlatibor Mountains (Dinaridic Ophiolite Belt) west of the Drina-Ivanjica unit yield Late Triassic radiolarian ages. The microfacies characteristics of the radiolarites show pure ribbon radiolarites without crinoids or thin-shelled bivalves. Beside their age and the preservation of the radiolarians this points to a deposition of the radiolarites on top of the oceanic crust of the Neo-Tethys, which started to open in the Late Anisian. South of the study area the ophiolitic mélange (Gostilje-Ljubiš-Visoka-Radoševo mélange) contains a mixture of blocks of 1) oceanic crust, 2) Middle and Upper Triassic ribbon radiolarites, and 3) open marine limestones from the continental slope. On the basis of this composition we can conclude that the Upper Triassic radiolarite clasts derive either from 1) the younger parts of the sedimentary succession above the oceanic crust near the continental slope or, more convincingly 2) the sedimentary cover of ophiolites in a higher nappe position, because Upper Triassic ribbon radiolarites are only expected in more distal oceanic areas. The ophiolitic mélange in the study area overlies different carbonate blocks of an underlying carbonate-clastic mélange (Sirogojno mélange). We date and describe three localities with different Upper Triassic radiolarite clasts in a mélange, which occurs A) on top of Upper Triassic fore-reef to reefal limestones (Dachstein reef), B) between an Upper Triassic reefal limestone block and a Lower Carnian reef limestone (Wetterstein reef), and C) in fissures of an Upper Triassic lagoonal to back-reef limestone (Dachstein lagoon). The sedimentary features point to a sedimentary and not to a tectonic emplacement of the ophiolitic mélange (= sedimentary mélange) filling the rough topography of the topmost carbonate-clastic mélange below. The block spectrum of the underlying and slightly older

Chromian spinels in highly altered ultramafic rocks from the Sartohay ophiolitic mélange, Xinjiang, NW China

Science.gov (United States)

Qiu, Tian; Zhu, Yongfeng

2018-06-01

The Sartohay ophiolitic mélange is located in western Junggar (Xinjiang province, NW China), which is a major component of the core part of the Central Asian Orogenic Belt (CAOB). Chromian spinels in serpentinite, talc schist, carbonate-talc schist and listwaenite in Sartohay ophiolitic mélange retain primary compositions with Cr# of 0.39-0.65, Mg# = 0.48-0.67, and Fe3+# evolution of chromian spinels in highly altered ultramafic rocks from the Sartohay ophiolitic mélange. Chromian spinels in serpentinite and talc schist were rimmed by Cr-magnetite, which was dissolved completely during transformation from serpentinite/talc schist to listwaenite. Chromian spinels were then transformed into Fe2+-rich chromite in shear zones, which characterized by high fluid/rock ratios. This Fe2+-rich chromite and/or chromian spinels could then be transformed into Fe3+-rich chromite in oxidizing conditions at shallow levels.

Lenna Kuurmaa üllatas / Ode Alt

Index Scriptorium Estoniae

Alt, Ode

2008-01-01

Rainer Sarneti noortefilm "Kuhu põgenevad hinged?", stsenaariumi aluseks on Aidi Valliku romaanid Annist, kaasstsenarist Peeter Sauter, osades Ragne Veensalu, Lenna Kuurmaa jt. Filmi tootja Exitfilm. Loo autor on Tartu Descartes'i Lütseumi 12. klassi õpilane

Profanum et Promissio : het begrip wereld in de missionaire ecclesiologieën van Hans Hoekendijk, Hans Jochen Margull en Ernst Lange

NARCIS (Netherlands)

Petter, Frank Anthonie

2002-01-01

Profanum et Promissio The concept of ‘world’ in the missionary ecclesiologies of Hans Hoekendijk, Hans Jochen Margull and Ernst Lange. This study deals with the concept of ‘world’ in the missionary ecclesiologies of Hans Hoekendijk (1912-1975), Hans Jochen Margull (1925-1982) and Ernst Lange

Localized Failure Promoted by Heterogeneous Stresses in Tectonic Mélanges

Science.gov (United States)

Phillips, N. J.; Rowe, C. D.; Ujiie, K.

2017-12-01

Within the shallow (PLC) toolbox developed at the University of Maine, which uses Asymptotic Expansion Homogenization (AEH) over a finite element mesh to determine the instantaneous stress distributions in a multiphase system. We model the shale matrix mélange to be deforming through a modified flow law for viscous creep based on coupled frictional sliding and pressure solution, where at a strain rate of 10-12 s-1 the flow stress is 10 MPa under the temperature (190 ºC) and pressure ( 100 MPa) conditions during deformation, and describe the behaviour of the basaltic blocks using experimentally-derived power law flow laws. The results show that at the strain rates calculated based on plate-rate motion, differential stresses high enough to cause comminution of the basalts ( 300 MPa) correspond strongly to areas around the blocks with basalt derived cataclasites. Within the basalt derived cataclasites, thin zones of ultracataclasite record localized slip. We hypothesize that the heterogeneous stress distributions within subduction mélanges: 1) fractures the strong basalt thereby facilitating weakening through fluid-rock interactions, and 2) promotes localized slip (and occasionally seismicity) within these zones of altered basalt along the margins of strong intact basalt.

Bloei-inductie bij Chrysant onder lange dag : toepassing van LED-licht technologie

NARCIS (Netherlands)

Ieperen, van W.; Hogewoning, S.W.; Dam, ten E.

2011-01-01

Deze publicatie beschrijft een onderzoek naar daglengte verlenging tijdens de korte dag bij chrysant met behoud van bloei door sturing met speciale LED belichting. In klimaatkamerproeven met LEDs (zonder natuurlijk licht) kon bij Chrysant bloemknopaanleg worden geïnduceerd onder een lange dag (LD),

Infant Attentional Behaviours as Prognostic Indicators in Cornelia-de-Lange Syndrome

Science.gov (United States)

Sarimski, Klaus

2007-01-01

Background: Cornelia-de-Lange syndrome is a rare congenital syndrome with poor social relatedness as one of several characteristics of its behavioural phenotype. Methods: Video observations were collected from seven children in their first year of life and again with age 2-4 years. Data were analysed for distribution of object-related and social…

Science et littérature : mélange des genres

OpenAIRE

Lissalde, Claire

2016-01-01

Cet article expose les démarches et les enjeux de l’organisation de l’exposition Science/Fiction, voyage au cœur du vivant par l’INSERM. Il souligne également l’innovation proposée par une médiation qui utilise le mélange des genres littéraires et scientifiques pour atteindre son public.

Facial Expression of Affect in Children with Cornelia de Lange Syndrome

Science.gov (United States)

Collis, L.; Moss, J.; Jutley, J.; Cornish, K.; Oliver, C.

2008-01-01

Background: Individuals with Cornelia de Lange syndrome (CdLS) have been reported to show comparatively high levels of flat and negative affect but there have been no empirical evaluations. In this study, we use an objective measure of facial expression to compare affect in CdLS with that seen in Cri du Chat syndrome (CDC) and a group of…

A Malay boy with the Cornelia de Lange syndrome: clinical and molecular findings

NARCIS (Netherlands)

Bhuiyan, Z. A.; Zilfalil, B. A.; Hennekam, R. C. M.

2006-01-01

The Cornelia de Lange syndrome is a multiple congenital anomaly syndrome characterised by dysmorphic facial features, hirsutism, severe growth and developmental delays, and malformed upper limbs. The prevalence is estimated to be one per 10,000. Recently, several independent groups proved that

Herstel van lange termijn effecten van verzuring en vermesting in het droog zandlandschap

NARCIS (Netherlands)

Siepel, H.; Siebel, H.N.; Verstrael, T.; Burg, Van den A.; Vogels, J.

2009-01-01

Effectgerichte maatregelen zijn de afgelopen jaren succesvol ingezet tegen de korte termijn effecten van verzuring en vermesting in het droog zandlandschap. De accumulatie van zuur en meststoffen heeft echter ook een effect op lange termijn. Hoe zien deze effecten eruit en hoe kan herstelbeheer

Optimization Analysis on Parameters of Cleaning Sieve of Rape Combine of "Bi Lang 4LZ(Y)-1.0"

OpenAIRE

Wu Mingliang; Tang Lun; Guan Chunyun; Tang Chuzhou

2014-01-01

Against the phenomenon of high impurity rate and cane and pod shell are difficult to discharge at the end of the sieve for rape combine of "Bi Lang 4LZ(Y)-1.0". This study take cleaning sieve of rape combine of "Bi Lang 4LZ(Y)-1.0" as study object, analyzed the movement of materials on sieve, established the virtual prototype model of the cleaning sieve of this rape combine, taken materials and cleaning sieve all at the best motion state as constraint conditions and optimized the structure an...

Self-Injurious Behavior, Self-Restraint, and Compulsive Behaviors in Cornelia de Lange Syndrome.

Science.gov (United States)

Hyman, Philippa; Oliver, Chris; Hall, Scott

2002-01-01

Analysis of questionnaires completed by caregivers of 77 individuals with Cornelia de Lange syndrome in the United Kingdom found a significant association between self-injurious behaviors and self-restraint, and those displaying both behaviors displayed significantly more compulsions than did those not exhibiting them. Findings extend the…

Self-Injurious Behaviour in Cornelia De Lange Syndrome: 1. Prevalence and Phenomenology

Science.gov (United States)

Oliver, C.; Sloneem, J.; Hall, S.; Arron, K.

2009-01-01

Background: Self-injurious behaviour is frequently identified as part of the behavioural phenotype of Cornelia de Lange syndrome (CdLS). We conducted a case-control study of the prevalence and phenomenology of self-injurious behaviour (SIB) in CdLS. Methods: A total of 54 participants with CdLS were compared with 46 individuals who were comparable…

Historical study: Cornelia C. de Lange (1871-1950)--a pioneer in clinical genetics

NARCIS (Netherlands)

de Knecht-van Eekelen, A.; Hennekam, R. C.

1994-01-01

The life and work in the field of clinical genetics of one of the most outstanding Dutch pediatricians of the first half of the twentieth century, Cornelia C. de Lange (1871-1950), is described against the background of the development of pediatrics, anthropogenetics, and clinical genetics in the

Zwischen Aufbegehren und bürgerlicher Rolle: die Lebensgemeinschaft von Helene Lange und Gertrud Bäumer The partnership of Helene Lange und Gertrud Bäumer: a both rebellious and domestic way of life

Directory of Open Access Journals (Sweden)

Mechthilde Vahsen

2001-07-01

Full Text Available Die Forschungsarbeiten analysieren private weibliche Beziehungsformen und ihre Bedeutung für die erste deutsche Frauenbewegung. Im Zentrum der Betrachtung steht eines der wichtigsten Führungspaare dieser Zeit: Helene Lange und Gertrud Bäumer. Die Dissertation von Göttert liefert einen wichtigen Beitrag zur Netzwerkforschung, Schaser beschäftigt sich in ihrer innovativen Studie mit der Lebensgemeinschaft der beiden Frauen, die sie in die frauenbewegten und politischen Kontexte einordnet.These studies analyse the private aspects of female relationship and their significance for the first wave of the German women’s movement. The focus is on the leading couple at that particular time: Helene Lange and Gertrud Bäumer. The dissertation by Göttert contributes an important piece to the network research, whereas Schaser describes in her innovative study the partnership of the two women, which is strongly related to the feminist and political context.

Analysis of Intentional Communication in Severely Handicapped Children with Cornelia-de-Lange Syndrome.

Science.gov (United States)

Sarimski, Klaus

2002-01-01

Intentional communicative acts were assessed in 13 children (ages 2-8) with Cornelia-de-Lange syndrome with a severe mental disability and compared to children with Down and 5p syndromes. The mean number of intentional communicative acts was significantly lower. Analysis of play behaviors revealed the differences were specific for the…

Health and Sleep Problems in Cornelia de Lange Syndrome: A Case Control Study

Science.gov (United States)

Hall, S. S.; Arron, K.; Sloneem, J.; Oliver, C.

2008-01-01

Background: Self-injury, sleep problems and health problems are commonly reported in Cornelia de Lange Syndrome (CdLS) but there are no comparisons with appropriately matched participants. The relationship between these areas and comparison to a control group is warranted. Method: 54 individuals with CdLS were compared with 46 participants with…

The Behavioural Phenotype of Cornelia de Lange Syndrome: A Study of 56 Individuals

Science.gov (United States)

Basile, Emanuele; Villa, L.; Selicorni, A.; Molteni, M.

2007-01-01

Background: Few studies have investigated functional and behavioural variables of Cornelia de Lange Syndrome (CdLS) in a large sample of individuals. The aim of this study is to provide greater insight into the clinical, behavioural and cognitive characteristics that are associated with CdLS. Methods: In total, 56 individuals with CdLS…

Cornelia de Lange syndrome and esophageal stricture in a 9-year-old child

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R. G. Artamonov

2016-01-01

Full Text Available Children with rare diseases may be found to have various malformations, including those of the gastrointestinal tract. The authors followed up a 9‑year-old child with Cornelia de Lange syndrome, who was found to have esophageal stricture with the development of gastroesophageal reflux and esophagitis.

Normal Language Skills and Normal Intelligence in a Child with de Lange Syndrome.

Science.gov (United States)

Cameron, Thomas H.; Kelly, Desmond P.

1988-01-01

The subject of this case report is a two-year, seven-month-old girl with de Lange syndrome, normal intelligence, and age-appropriate language skills. She demonstrated initial delays in gross motor skills and in receptive and expressive language but responded well to intensive speech and language intervention, as well as to physical therapy.…

Scaly fabrics and veins of the Mugi and Makimine mélanges in the Shimanto belt, SW Japan

Science.gov (United States)

Ramirez, G. E.; Fisher, D. M.; Yamaguchi, A.; Kimura, G.

2016-12-01

Two regionally extensive ancient subduction fault zones provide a microstructural record of the plate boundary deformation associated with underthrusting. These rocks exhibit many of the characteristics associated with exposed ancient subduction fault zones worldwide, including: (1) σ1 is near orthogonal to the deformation fabric (2) there are microstructurally pervasive quartz and calcite filled veins concentrated in coarser blocks and along extensional jogs on slip surfaces, (3) evidence for local diffusion of silica sourced from web-like arrays of slip surfaces (i.e., scaly fabrics), and (4) evidence for cycles of cracking and sealing that record cyclic variations in stress. We present new backscatter SEM observations of scaly fabrics from two ancient subduction-related shear zones from the Shimanto Belt in Japan that exemplify these characteristics and represent the full temperature range of the seismogenic zone: 1) the Mugi mélange (lower ( 130-150 °C) and upper ( 170-200 °C) sections) and 2) Makimine mélange (peak temperatures of 340 °C). The Mugi mélange is an underplated duplex consisting of two horses separated by an OOST. The upper section is bounded at the top by a pseudotachylite-bearing paleodécollement. The Makimine mélange was underplated at the downdip limit of the seismogenic zone. The scaly fabrics associated with these shear zones display significantly different microstructural characteristics. A slip surface from along the upper Mugi is characterized by broader ( 20-30 μm), zones of quartz-poor, anastomosing shear zones composed of fine-grained (0.5-2 μm in length) phyllosilicates. The Makimine mélange exhibits thinner (10-20 μm), anastomosing shear zones with coarser (1-4 μm in length) phyllosilicate grains that are more strongly oriented into parallelism with slip surfaces. Quartz veins are pervasively developed in more competent blocks and are oriented at near perpendicular angles to the slip surfaces. Microstructural analyses

Self-Injurious Behaviour in Cornelia De Lange Syndrome: 2. Association with Environmental Events

Science.gov (United States)

Sloneem, J.; Arron, K.; Hall, S. S.; Oliver, C.

2009-01-01

Background: Self-injurious behaviour is commonly seen in Cornelia de Lange syndrome (CdLS). However, there has been limited research into the aetiology of self-injury in CdLS and whether environmental factors influence the behaviour. Methods: We observed the self-injury of 27 individuals with CdLS and 17 participants who did not have CdLS matched…

Rein Lang: Eesti kõige väärtuslikum ressurss on mõistus / Rein Lang ; interv. Peep Lillemägi ; komment. Siim Kallas, Jüri Pihl, Väino Linde

Index Scriptorium Estoniae

Lang, Rein, 1957-

2009-01-01

Justiitsminister Rein Lang vastab küsimustele, mis puudutavad Ameerika Ühendriike kui vabaduse kantsi, ettevõtlusvabadust Ameerika Ühendriikides ja Eestis, tööd justiitsministrina, varasemat karjääri, Eesti põhiseaduse loomist, Euroopa Liidu aluslepingu välja töötamist, avaliku võimu rolli tänapäeva maailmas ning Eesti jõudmist Euroopa rikkamate riikide hulka

Unraveling the history of complex zoned garnets from the North Motagua Mélange (Guatemala)

Science.gov (United States)

Barickman, M. H.; Martin, C.; Flores, K. E.; Harlow, G. E.; Bonnet, G.

2016-12-01

The Guatemala Suture Zone (GSZ) is situated in central Guatemala, between the North American and Caribbean plates. Two serpentinite mélanges straddle the Motagua Fault system: the North Motagua Mélange (NMM) and the South Motagua Mélange (SMM). In this study, chemically zoned garnet grains from four eclogite blocks from the NMM were analyzed by EMPA for major elements and LA-ICP-MS for trace elements to unravel the geological history of the eclogites. These eclogites typically consist of euhedral to subhedral garnets, partly retrogressed omphacite grains, and accessory minerals such as phengite and epidote as inclusions in garnet. EBSD was employed to examine apparent garnet inclusions in garnet. The garnet grains in NMM eclogites display complex chemical zonations: all grains roughly show a spessartine-rich core, an almandine-rich core and/or intermediate zone, and a pyrope and grossular-rich rim. Additionally, crystal resorption can be observed between the different zones, and the pyrope-grossular rim can display oscillatory zoning. Finally, grossular-rich zones (crystallographically syntactic) within garnet are present in all studied samples. REE and spider diagrams do not show any significant difference in the patterns of the different zones within the garnet, or indicating that the chemical environment from which each garnet zone grew was broadly the same. The lack of significant variation in LILE content indicates that a fluid influx during garnet growth is unlikely. Consequently, we interpret that garnet grains grew in a largely closed system; however, the presence of the grossular-rich zones, argues for occasional excursions into conditions when either two garnets crystallized or Ca-rich overgrowths that were largely resorbed prior to subsequent continued garnet growth.

Toxicity of phosphor esters: Willy Lange (1900-1976) and Gerda von Krueger (1907-after 1970).

Science.gov (United States)

Petroianu, G A

2010-10-01

In 1851 Williamson serendipitously discovered a new and efficient way to produce ethers using ethyl iodide and potassium salts. Based on this new synthetic approach, the Frenchman Philippe de Clermont and the Muscovite Wladimir Moschnin, both élèves of Adolphe Wurtz in his Paris School of Chemistry, achieved the synthesis of the first ester of pyrophosphoric acid (TEPP). de Clermont "tasted" the new compound and although TEPP is a potent cholinesterase inhibitor he failed to recognize its toxicity. Almost a century later, in 1932, Willy Lange (1900-1976) and his graduate student Gerda v. Krueger (1907-after 1970) described the toxicity of organophosphonates. While the classic paper of the two "Uber Ester der Monofluorphosphorsäure." is cited by almost everybody working in the field, little is known about Lange and almost nothing about v. Krueger. This brief communication attempts to shed some light on the life of both.

Dental Management of Cornelia de Lange Syndrome: A Rare Case Report

OpenAIRE

Sandhu, Meera; Nagpal, Mehak; Gulia, Shweta; Sachdev, Vinod

2015-01-01

Cornelia de Lange syndrome (CdLS) is a rare, multiple congenital defect often called as Amsterdam dwarfism. The physical phenotype of CdLS includes low birth body weight, short stature and facio-cranial dysmorphia. The diagnosis of the syndrome is based on clinical grounds as there is no biochemical or chromosomal markers for CDLS that makes its diagnosis more complicated. The purpose of this paper is to present a clinical report of a boy emphasizing the importance of multidisciplinary approa...

Verborgen carrières; oudere kunstenaars en een leven lang leren : een narratief PhD-onderzoek naar levenslang en levensbreed leren binnen de gevorderde beroepspraktijk van beeldende kunstenaars

NARCIS (Netherlands)

Delfgaauw, Leo

2014-01-01

Oudere Kunstenaars en een leven lang leren. ​Verborgen carrières: oudere kunstenaars en een leven lang leren. Een narratief-biografisch onderzoek naar levenslang en levensbreed leren binnen de gevorderde beroepspraktijk van beeldende kunstenaars. PhD-research Leo Delfgaauw. Promotoren: prof. dr.

Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts.

Science.gov (United States)

Kline, Antonie D; Calof, Anne L; Schaaf, Cheri A; Krantz, Ian D; Jyonouchi, Soma; Yokomori, Kyoko; Gauze, Maria; Carrico, Cheri S; Woodman, Julie; Gerton, Jennifer L; Vega, Hugo; Levin, Alex V; Shirahige, Katsuhiko; Champion, Michele; Goodban, Marjorie T; O'Connor, Julia T; Pipan, Mary; Horsfield, Julia; Deardorff, Matthew A; Ishman, Stacey L; Dorsett, Dale

2014-06-01

Cornelia de Lange syndrome (CdLS) is the prototype for the cohesinopathy disorders that have mutations in genes associated with the cohesin subunit in all cells. Roberts syndrome is the next most common cohesinopathy. In addition to the developmental implications of cohesin biology, there is much translational and basic research, with progress towards potential treatment for these conditions. Clinically, there are many issues in CdLS faced by the individual, parents and caretakers, professionals, and schools. The following abstracts are presentations from the 5th Cornelia de Lange Syndrome Scientific and Educational Symposium on June 20-21, 2012, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting, Lincolnshire, IL. The research committee of the CdLS Foundation organizes the meeting, reviews and accepts abstracts and subsequently disseminates the information to the families. In addition to the basic science and clinical discussions, there were educationally-focused talks related to practical aspects of management at home and in school. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. © 2014 Wiley Periodicals, Inc.

Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity.

Science.gov (United States)

Kwon, Yong-Soo; Cho, Young-Nan; Kim, Moon-Ju; Jin, Hye-Mi; Jung, Hyun-Ju; Kang, Jeong-Hwa; Park, Ki-Jeong; Kim, Tae-Jong; Kee, Hae Jin; Kim, Nacksung; Kee, Seung-Jung; Park, Yong-Wook

2015-05-01

Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections. The aims of this study were to examine the levels of MAIT cells in pulmonary tuberculosis (TB) and nontuberculous mycobacteria (NTM) lung disease patients, to evaluate the clinical relevance of MAIT cell levels, and to investigate the functions of MAIT cells. Patients with pulmonary TB (n = 35), NTM (n = 29), and healthy controls (n = 75) were enrolled in the study. MAIT cell levels and functions were measured by flow cytometry. Circluating MAIT cell levels were found to be reduced in TB and NTM patients. MAIT cell deficiency reflects a variety of clinical conditions. In particular, MAIT cell numbers were significantly correlated with sputum AFB positivity, extent of disease, hemoglobin levels, lymphocyte counts, CRP and ESR levels. MAIT cells in TB patients failed to produce interferon-γ irrespective of the mode of stimulation, whereas NTM patients displayed a defect in MR1-dependent signaling pathway. Notably, an elevated expression of programmed death-1 was also associated with MAIT cell deficiency in TB. This study shows that MAIT cells are numerically and functionally deficient in TB and NTM patients and these deficiencies could contribute to immune system dysreguation in mycobacterial infection. Copyright © 2015 Elsevier Ltd. All rights reserved.

Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein-Taybi Syndromes

Science.gov (United States)

Crawford, Hayley; Waite, Jane; Oliver, Chris

2017-01-01

Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein-Taybi syndromes (RTS), and compared the symptomatology to normative data for…

Activation, Impaired Tumor Necrosis Factor-α Production, and Deficiency of Circulating Mucosal-Associated Invariant T Cells in Patients with Scrub Typhus.

Science.gov (United States)

Kang, Seung-Ji; Jin, Hye-Mi; Won, Eun Jeong; Cho, Young-Nan; Jung, Hyun-Ju; Kwon, Yong-Soo; Kee, Hae Jin; Ju, Jae Kyun; Kim, Jung-Chul; Kim, Uh Jin; Jang, Hee-Chang; Jung, Sook-In; Kee, Seung-Jung; Park, Yong-Wook

2016-07-01

Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections. However, little is known about the role of MAIT cells in Orientia tsutsugamushi infection. Hence, the aims of this study were to examine the level and function of MAIT cells in patients with scrub typhus and to evaluate the clinical relevance of MAIT cell levels. Thirty-eight patients with scrub typhus and 53 health control subjects were enrolled in the study. The patients were further divided into subgroups according to disease severity. MAIT cell level and function in the peripheral blood were measured by flow cytometry. Circulating MAIT cell levels were found to be significantly reduced in scrub typhus patients. MAIT cell deficiency reflects a variety of clinical conditions. In particular, MAT cell levels reflect disease severity. MAIT cells in scrub typhus patients displayed impaired tumor necrosis factor (TNF)-α production, which was restored during the remission phase. In addition, the impaired production of TNF-α by MAIT cells was associated with elevated CD69 expression. This study shows that circulating MAIT cells are activated, numerically deficient, and functionally impaired in TNF-α production in patients with scrub typhus. These abnormalities possibly contribute to immune system dysregulation in scrub typhus infection.

Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: abstracts from the 2014 Scientific and Educational Symposium.

Science.gov (United States)

Kline, Antonie D; Calof, Anne L; Lander, Arthur D; Gerton, Jennifer L; Krantz, Ian D; Dorsett, Dale; Deardorff, Matthew A; Blagowidow, Natalie; Yokomori, Kyoko; Shirahige, Katsuhiko; Santos, Rosaysela; Woodman, Julie; Megee, Paul C; O'Connor, Julia T; Egense, Alena; Noon, Sarah; Belote, Maurice; Goodban, Marjorie T; Hansen, Blake D; Timmons, Jenni Glad; Musio, Antonio; Ishman, Stacey L; Bryan, Yvon; Wu, Yaning; Bettini, Laura R; Mehta, Devanshi; Zakari, Musinu; Mills, Jason A; Srivastava, Siddharth; Haaland, Richard E

2015-06-01

Cornelia de Lange Syndrome (CdLS) is the most common example of disorders of the cohesin complex, or cohesinopathies. There are a myriad of clinical issues facing individuals with CdLS, particularly in the neurodevelopmental system, which also have implications for the parents and caretakers, involved professionals, therapists, and schools. Basic research in developmental and cell biology on cohesin is showing significant progress, with improved understanding of the mechanisms and the possibility of potential therapeutics. The following abstracts are presentations from the 6th Cornelia de Lange Syndrome Scientific and Educational Symposium, which took place on June 25-26, 2014, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting in Costa Mesa, CA. The Research Committee of the CdLS Foundation organizes the meeting, reviews and accepts abstracts, and subsequently disseminates the information to the families through members of the Clinical Advisory Board. In addition to the scientific and clinical discussions, there were educationally focused talks related to practical aspects of behavior and development. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. © 2015 Wiley Periodicals, Inc.

Validation of the Eddy Viscosity and Lange Wake Models using Measured Wake Flow Characteristics Behind a Large Wind Turbine Rotor

Energy Technology Data Exchange (ETDEWEB)

Jeon, Sang Hyeon; Kim, Bum Suk; Huh, Jong Chul [Jeju National Univ., Jeju (Korea, Republic of); Go, Young Jun [Hanjin Ind, Co., Ltd., Yangsan (Korea, Republic of)

2016-01-15

The wake effects behind wind turbines were investigated by using data from a Met Mast tower and the SCADA (Supervisory Control and Data Acquisition) system for a wind turbine. The results of the wake investigations and predicted values for the velocity deficit based on the eddy viscosity model were compared with the turbulence intensity from the Lange model. As a result, the velocity deficit and turbulence intensity of the wake increased as the free stream wind speed decreased. In addition, the magnitude of the velocity deficit for the center of the wake using the eddy viscosity model was overestimated while the turbulence intensity from the Lange model showed similarities with measured values.

Aqueous Solubility of Hydrocarbon Mixtures Solubilité dans l'eau de mélanges d'hydrocarbures

Directory of Open Access Journals (Sweden)

De Hemptinne J. C.

2006-12-01

Full Text Available The solubility of hydrocarbon components in water is of great importance for the environmental sciences. Its prediction is usually based on using the pure component solubilities and the mole fraction of the components in the mixture. While the pure component solubilities are generally well known, few data exist on the solubility of mixtures. Using a simple relationship leads to an underestimation of the true solubility. This paper presents some new data on the aqueous solubility of binary hydrocarbon mixtures. Using a rigorous thermodynamic analysis, we explain the observed behavior, as well as other data from the literature, including the solubility of jet fuel mixtures in water. The activity coefficient models used for this purpose are NRTL, UNIQUAC and UNIFAC. Considering the small concentration in oil of some very soluble substances, the activity coefficient can become significant and thus explain the fact that solubilities of some component may be as much as twice as large as expected. La solubilité de composés hydrocarbonés dans l'eau est d'une importance cruciale pour les sciences environnementales. Sa prévision est généralement basée sur la solubilité des constituants purs et de leur fraction molaire en mélange. La solubilité des composés purs est généralement bien connue, mais peu de données ont été publiées concernant les mélanges. L'utilisation d'une relation simple conduit à une sous-estimation de la solubilité réelle. Cet article présente quelques données nouvelles de solubilités de mélanges hydrocarbonés simples. Une analyse thermodynamique rigoureuse permet de décrire la solubilité observée, aussi bien pour des mélanges modèles que pour des kérosènes. Les modèles de coefficient d'activité utilisés dans ce but sont NRTL, UNIQUAC et UNIFAC. Étant donné la faible concentration de certains constituants dans l'huile, leurs coefficients d'activité peut devenir important. Ceci explique une

Neotethyan rifting-related ore occurrences: study of an accretionary mélange complex (Darnó Unit, NE Hungary

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Kiss Gabriella B.

2016-02-01

Full Text Available The geology of the NE Hungarian Darnó Unit is rather complicated, as it is composed mostly of a Jurassic accretionary mélange complex, according to the most recent investigations. The magmatic and sedimentary rock blocks of the mélange represent products of different evolutionary stages of the Neotethys; including Permian and Triassic sedimentary rocks of marine rifting related origin, Triassic pillow basalt of advanced rifting related origin and Jurassic pillow basalt originated in back-arc-basin environment. This small unit contains a copper-gold occurrence in the Permian marly-clayey limestone, an iron enrichment in the Triassic sedimentary succession, a copper-silver ore occurrence in Triassic pillow basalts and a copper ore indication, occurring both in the Triassic and Jurassic pillow basalts. The present study deals with the Cu(-Ag occurrence in the Triassic basalt and the Fe occurrence in the Triassic sedimentary succession. The former shows significant similarities with the Michigan-type mineralizations, while the latter has typical characteristics of the Fe-SEDEX deposits. All the above localities fit well into the new geological model of the investigated area. The mineralizations represent the different evolutionary stages of the Neotethyan rifting and an epigenetic, Alpine metamorphism-related process and their recent, spatially close position is the result of the accretionary mélange formation. Thus, the Darnó Unit represents a perfect natural laboratory for studying and understanding the characteristic features of several different rifting related ore forming processes.

De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes

DEFF Research Database (Denmark)

Gil-Rodríguez, María Concepción; Deardorff, Matthew A; Ansari, Morad

2015-01-01

Cornelia de Lange syndrome (CdLS) is characterized by facial dysmorphism, growth failure, intellectual disability, limb malformations, and multiple organ involvement. Mutations in five genes, encoding subunits of the cohesin complex (SMC1A, SMC3, RAD21) and its regulators (NIPBL, HDAC8), account ...

Maximal exercise increases mucosal associated invariant T cell frequency and number in healthy young men.

Science.gov (United States)

Hanson, Erik D; Danson, Eli; Nguyen-Robertson, Catriona V; Fyfe, Jackson J; Stepto, Nigel K; Bartlett, David B; Sakkal, Samy

2017-11-01

Mucosal associated invariant T (MAIT) cells have properties of the innate and acquired immune systems. While the response to vigorous exercise has been established for most leukocytes, MAIT cells have not been investigated. Therefore, the purpose was to determine if MAIT cell lymphocytosis occurs with acute maximal aerobic exercise and if this response is influenced by exercise duration, cardiovascular fitness, or body composition. Twenty healthy young males with moderate fitness levels performed an extended graded exercise test until volitional fatigue. Peripheral blood mononuclear cells were isolated from venous blood obtained prior and immediately after exercise and were labeled to identify specific T cell populations using flow cytometry. The percentage of MAIT cells relative to total T cells significantly increased from 3.0 to 3.8% and absolute MAIT cell counts increased by 2.2-fold following maximal exercise. MAIT cell subpopulation proportions were unchanged with exercise. Within cytotoxic T lymphocytes (CTL), MAIT cells consisted of 8% of these cells and this remained constant after exercise. MAIT cell counts and changes with exercise were not affected by body composition, VO 2peak , or exercise duration. Maximal exercise doubled MAIT cell numbers and showed preferential mobilization within total T cells but the response was not influenced by fitness levels, exercise duration, or body composition. These results suggest that acute exercise could be used to offset MAIT cell deficiencies observed with certain pathologies. MAIT cells also make up a substantial proportion of CTLs, which may have implications for cytotoxicity assays using these cells.

Effects of Social Context on Social Interaction and Self-Injurious Behavior in Cornelia de Lange Syndrome

Science.gov (United States)

Arron, Kate; Oliver, Chris; Hall, Scott; Sloneem, Jenny; Forman, Debbie; McClintock, Karen

2006-01-01

Cornelia de Lange syndrome is reported to be associated with self-injurious behavior (SIB) and social avoidance. We used analog methodology to examine the effect of manipulating adult social contact on social communicative behaviors and SIB in 16 children with this syndrome. For 9 participants engagement behavior was related to levels of adult…

Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161++TCR iVα7.2+ Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection

Directory of Open Access Journals (Sweden)

Yean K. Yong

2018-03-01

Full Text Available Mucosal-associated invariant T (MAIT cells, defined as CD161++TCR iVα7.2+ T cells, play an important role in the innate defense against bacterial infections, and their functionality is impaired in chronic viral infections. Here, we investigated the frequency and functional role of MAIT cells in chronic hepatitis B virus (HBV infection. The peripheral CD3+CD161++TCR iVα7.2+ MAIT cells in chronic HBV-infected patients and healthy controls were phenotypically characterized based on CD57, PD-1, TIM-3, and CTLA-4, as well as HLA-DR and CD38 expression. The frequency of MAIT cells was significantly decreased among chronic HBV-infected individuals as compared to controls. Expression of CD57, PD-1, CTLA-4, as well as HLA-DR and CD38 on MAIT cells was significantly elevated in chronic HBV-infected individuals relative to controls. The percentage of T cell receptor (TCR iVα7.2+ CD161+ MAIT cells did not correlate with HBV viral load but inversely with HLA-DR on CD4+ T cells and MAIT cells and with CD57 on CD8+ T cells suggesting that decrease of MAIT cells may not be attributed to direct infection by HBV but driven by HBV-induced chronic immune activation. The percentage and expression levels of PD-1 as well as CTLA-4 on MAIT cells inversely correlated with plasma HBV-DNA levels, which may suggest either a role for MAIT cells in the control of HBV infection or the effect of HBV replication in the liver on MAIT cell phenotype. We report that decrease of TCR iVα7.2+ MAIT cells in the peripheral blood and their functions were seemingly impaired in chronic HBV-infected patients likely because of the increased expression of PD-1.

Ormen Lange hot tap - a world record

Energy Technology Data Exchange (ETDEWEB)

Apeland, Kjell Edvard

2010-07-01

For the last 10 years Statoil have been developing a new concept for performing subsea Hot Tap operations remotely controlled. The system was first used offshore in 2008 during a partly diver assisted operation, connecting the Tampen Link pipeline to the Statfjord Intrafield pipeline. In July 2009, the Hot Tap System successfully performed two remotely controlled Hot Taps, on a world record depth of 860 meters on the Ormen Lange field operated by Shell. The Hot Tap technology enables existing pipeline architecture to be modified, without interfering with the current production. Most of the technology is depth independent and the system is currently qualified to 1000 meter depth. Phase II of this project which involves development and construction of a retrofit Tee, thus enabling installation and welding of a Tee on an unprepared pipeline is well underway. This presentation will describe experiences from the development of the Remote Hot Tap system and give an overview of the offshore operations leading to the conclusion of the world's deepest Hot Taps. (Author)

De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes

NARCIS (Netherlands)

Gil-Rodriguez, M.C.; Deardorff, M.A.; Ansari, M.; Tan, C.A.; Parenti, I.; Baquero-Montoya, C.; Ousager, L.B.; Puisac, B.; Hernandez-Marcos, M.; Teresa-Rodrigo, M.E.; Marcos-Alcalde, I.; Wesselink, J.J.; Lusa-Bernal, S.; Bijlsma, E.K.; Braunholz, D.; Bueno-Martinez, I.; Clark, D.; Cooper, N.S.; Curry, C.J.; Fisher, R.; Fryer, A.; Ganesh, J.; Gervasini, C.; Gillessen-Kaesbach, G.; Guo, Y.; Hakonarson, H.; Hopkin, R.J.; Kaur, M.; Keating, B.J.; Kibaek, M.; Kinning, E.; Kleefstra, T.; Kline, A.D.; Kuchinskaya, E.; Larizza, L.; Li, Y.R.; Liu, X.; Mariani, M.; Picker, J.D.; Pie, A.; Pozojevic, J.; Queralt, E.; Richer, J.; Roeder, E.; Sinha, A.; Scott, R.H.; So, J.; Wusik, K.A.; Wilson, L.; Zhang, J.; Gomez-Puertas, P.; Casale, C.H.; Strom, L.; Selicorni, A.; Ramos, F.J.; Jackson, L.G.; Krantz, I.D.; Das, S.; Hennekam, R.C.; Kaiser, F.J.; FitzPatrick, D.R.; Pie, J.

2015-01-01

Cornelia de Lange syndrome (CdLS) is characterized by facial dysmorphism, growth failure, intellectual disability, limb malformations, and multiple organ involvement. Mutations in five genes, encoding subunits of the cohesin complex (SMC1A, SMC3, RAD21) and its regulators (NIPBL, HDAC8), account for

Lugemisnoppeid: antropoloogia / Marek Tamm

Index Scriptorium Estoniae

Tamm, Marek, 1973-

2012-01-01

Tutvustus: Jürgenson, Aivar. Ladina rahva seas : Argentina ja sealsed eestlased. Tallinn, 2011 ; Annist, Aet. Otsides kogukonda sotsialismijärgses keskuskülas : arenguantropoloogiline uurimus. Tallinn : Tallinna Ülikooli Kirjastus, 2011. (Acta Universitatis Tallinnensis. Socialia) ; Hiiemäe, Reet. Kaitsemaagia eesti rahvausundis. Tallinn, 2012 ; Augé, Marc. Kohad ja mittekohad : sissejuhatus ülimodernsuse antropoloogiasse. Tallinn : Tallinna Ülikooli Kirjastus, 2012. (Bibliotheca controversiarum)

A 6-year-old boy with Cornelia de Lange syndrome and Coats disease: case report and review of the literature.

Science.gov (United States)

Stacey, Andrew W; Sparagna, Cristina; Borri, Melissa; Rizzo, Stanislao; Hadjistilianou, Theodora

2015-10-01

Cornelia de Lange syndrome (CdLS) can result in multiple congenital abnormalities and numerous ocular findings. We report the case of a 6-year-old boy with history of CdLS who presented with Coats disease. The findings in this case are compared to those found in the two previously reported cases of concomitant CdLS and Coats disease. The low incidence of these two disorders makes it highly unlikely that the connection is random in these 3 cases. The number of patients with both Cornelia de Lange syndrome and Coats disease is likely underestimated due to the difficulty in examining the peripheral retina in this patient population. Copyright © 2015 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

Analyzing the Effect of Spinning Process Variables on Draw Frame Blended Cotton Mélange Yarn Quality

Science.gov (United States)

Ray, Suchibrata; Ghosh, Anindya; Banerjee, Debamalya

2017-12-01

An investigation has been made to study the effect of important spinning process variables namely shade depth, ring frame spindle speed and yarn twist multiplier (TM) on various yarn quality parameters like unevenness, strength, imperfection, elongation at break and hairiness index of draw frame blended cotton mélange yarn. Three factors Box and Behnken design of experiment has been used to conduct the study. The quadratic regression model is used to device the statistical inferences about sensitivity of the yarn quality parameters to the different process variables. The response surfaces are constructed for depicting the geometric representation of yarn quality parameters plotted as a function of process variables. Analysis of the results show that yarn strength of draw frame blended cotton mélange yarn is significantly affected by shade depth and TM. Yarn unevenness is affected by shade depth and ring frame spindle speed. Yarn imperfection level is mainly influenced by the shade depth and spindle speed. The shade depth and yarn TM have shown significant impact on yarn hairiness index.

A Longitudinal Follow-Up Study of Affect in Children and Adults with Cornelia de Lange Syndrome

Science.gov (United States)

Nelson, Lisa; Moss, Jo; Oliver, Chris

2014-01-01

Studies of individuals with Cornelia de Lange syndrome (CdLS) have described changes in mood and behavior with age, although no empirical or longitudinal studies have been conducted. Caregivers of individuals with CdLS (N = 67), cri du chat syndrome (CdCS; N = 42), and Fragile X syndrome (FXS; N = 142) completed the Mood, Interest and Pleasure…

Kinematic analysis of mélange fabrics: examples and applications from the McHugh Complex, Kenai Peninsula, Alaska

Science.gov (United States)

Kusky, Timothy M.; Bradley, Dwight C.

1999-12-01

Permian to Cretaceous mélange of the McHugh Complex on the Kenai Peninsula, south-central Alaska includes blocks and belts of graywacke, argillite, limestone, chert, basalt, gabbro, and ultramafic rocks, intruded by a variety of igneous rocks. An oceanic plate stratigraphy is repeated hundreds of times across the map area, but most structures at the outcrop scale extend lithological layering. Strong rheological units occur as blocks within a matrix that flowed around the competent blocks during deformation, forming broken formation and mélange. Deformation was noncoaxial, and disruption of primary layering was a consequence of general strain driven by plate convergence in a relatively narrow zone between the overriding accretionary wedge and the downgoing, generally thinly sedimented oceanic plate. Soft-sediment deformation processes do not appear to have played a major role in the formation of the mélange. A model for deformation at the toe of the wedge is proposed in which layers oriented at low angles to σ1 are contracted in both the brittle and ductile regimes, layers at 30-45° to σ1 are extended in the brittle regime and contracted in the ductile regime, and layers at angles greater than 45° to σ1 are extended in both the brittle and ductile regimes. Imbrication in thrust duplexes occurs at deeper levels within the wedge. Many structures within mélange of the McHugh Complex are asymmetric and record kinematic information consistent with the inferred structural setting in an accretionary wedge. A displacement field for the McHugh Complex on the lower Kenai Peninsula includes three belts: an inboard belt of Late Triassic rocks records west-to-east-directed slip of hanging walls, a central belt of predominantly Early Jurassic rocks records north-south directed displacements, and Early Cretaceous rocks in an outboard belt preserve southwest-northeast directed slip vectors. Although precise ages of accretion are unknown, slip directions are compatible with

Pankur poris / Aet Annist

Index Scriptorium Estoniae

Annist, Aet

2008-01-01

Autor annab ülevaate ajalehe Financial Times kolumnisti Gillian Tetti artiklist, kus räägitakse sellest, et tänases pangandusettevõtete segaduses maksab jälgida ka panganduse esindajate kui professionaalse grupi enesekehtestamist ja selle läbikukkumist. Vt. ka Financial Times, 18.01.2008

TBT - gehalten en effecten bij de Gewone alikruik, de Gevlochten Fuikhoorn en de Purperslak langs de Nederlandse kust in 2011

NARCIS (Netherlands)

Hoek-van Nieuwenhuizen, van M.; Jol, J.G.

2011-01-01

Sinds 2005 analyseert IMARES in opdracht van Rijkswaterstaat het voorkomen van intersex bij de Gewone Alikruiken (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met organotinverbindingen vast te

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue

NARCIS (Netherlands)

Zhang, Miao; D'Aniello, Cristina; Verkerk, Arie O.; Wrobel, Eva; Frank, Stefan; Ward-van Oostwaard, Dorien; Piccini, Ilaria; Freund, Christian; Rao, Jyoti; Seebohm, Guiscard; Atsma, Douwe E.; Schulze-Bahr, Eric; Mummery, Christine L.; Greber, Boris; Bellin, Milena

2014-01-01

Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening cardiac arrhythmias. Patients display delayed cardiac repolarization, associated high risk of sudden death due to ventricular tachycardia, and congenital bilateral deafness. In contrast to the autosomal dominant

Jervell and Lange-Nielson Syndrome masquerading as intractable epilepsy

Directory of Open Access Journals (Sweden)

Jagdish P Goyal

2012-01-01

Full Text Available The long QT syndrome (LQTS is a cause of syncope and sudden death. Jervell and Lange-Nielson syndrome (JLNS is an uncommon form of LQTS, having autosomal recessive transmission, and is associated with congenital deafness. We report a case of JLNS in a child who presented to us with refractory epilepsy. The cardiac cause of seizures was suspected as the child was hypotensive and pulseless during the episode of seizures. The child was diagnosed as JLNS based on Schwartz diagnostic criteria for LQTS and congenital sensorineural deafness. The child responded well to β-blocker therapy. Antiepileptic drugs were stopped. The screening of family members with ECG revealed a QT interval more than required for diagnosis of LQTS but they were asymptomatic. All asymptomatic family members were also put on metoprolol. All of them showed great improvement with the reduction of the QT interval on ECG. The patient was doing well on immediate follow-up.

TBT-gehalten en effecten bij de Gewone Alikruik, de Gevlochten Fuikhoorn en de Purperslak langs de Nederlandse kust in 2012

NARCIS (Netherlands)

Hoek-van Nieuwenhuizen, van M.; Jol, J.G.; Kaag, N.H.B.M.

2013-01-01

Sinds 2005 analyseert IMARES in opdracht van Rijkswaterstaat (RIKZ, later de Waterdienst) het voorkomen van intersex bij de Gewone Alikruiken (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met

Simultaneous Analysis of the Behavioural Phenotype, Physical Factors, and Parenting Stress in People with Cornelia De Lange Syndrome

Science.gov (United States)

Wulffaert, J.; van Berckelaer-Onnes, I.; Kroonenberg, P.; Scholte, E.; Bhuiyan, Z.; Hennekam, R.

2009-01-01

Background: Studies into the phenotype of rare genetic syndromes largely rely on bivariate analysis. The aim of this study was to describe the phenotype of Cornelia de Lange syndrome (CdLS) in depth by examining a large number of variables with varying measurement levels. Virtually the only suitable multivariate technique for this is categorical…

Social Behavior and Characteristics of Autism Spectrum Disorder in Angelman, Cornelia de Lange, and Cri du Chat Syndromes

Science.gov (United States)

Moss, Joanna; Howlin, Patricia; Hastings, Richard Patrick; Beaumont, Sarah; Griffith, Gemma M.; Petty, Jane; Tunnicliffe, Penny; Yates, Rachel; Villa, Darrelle; Oliver, Chris

2013-01-01

We evaluated autism spectrum disorder (ASD) characteristics and social behavior in Angelman (AS; "n" ?=? 19; mean age ?=?10.35 years), Cornelia de Lange (CdLS; "n" ?=? 15; mean age ?=?12.40 years), and Cri du Chat (CdCS, also known as 5 p-syndrome; "n" ?=? 19; mean age ?=? 8.80 years) syndromes. The proportion of…

Bill Lang's contributions to acoustics at the International Business Machines Corp. (IBM) and to IBM in general

Science.gov (United States)

Nobile, Matthew A.; Chu, Richard C.

2005-09-01

Although Bill Lang's accomplishments and key roles in national and international standards and in the formation of INCE are widely recognized, sometimes it has to be remembered that for nearly 35 years he also had a ``day job'' at the IBM Corporation. His achievements at IBM were no less significant and enduring than those in external standards and professional societies. This paper will highlight some of the accomplishments and activities of Bill Lang as an IBM noise control engineer, the creator of the IBM Acoustics Lab in Poughkeepsie, the founder of the global Acoustics program at IBM, and his many other IBM leadership roles. Bill was also a long-serving IBM manager, with the full set of personnel issues to deal with, so his people-management skills were often called into play. Bill ended his long and fruitful IBM career at a high point. In 1988, he took an original idea of his to the top of IBM executive management, which led directly to the formation of the IBM Academy of Technology, today the preeminent body of IBM top technical leaders from around the world.

Effects of herbicides on Behr's metalmark butterfly, a surrogate species for the endangered butterfly, Lange's metalmark

International Nuclear Information System (INIS)

Stark, John D.; Chen Xuedong; Johnson, Catherine S.

2012-01-01

Lange's metalmark butterfly, Apodemia mormo langei Comstock, is in danger of extinction due to loss of habitat caused by invasive exotic plants which are eliminating its food, naked stem buckwheat. Herbicides are being used to remove invasive weeds from the dunes; however, little is known about the potential effects of herbicides on butterflies. To address this concern we evaluated potential toxic effects of three herbicides on Behr's metalmark, a close relative of Lange's metalmark. First instars were exposed to recommended field rates of triclopyr, sethoxydim, and imazapyr. Life history parameters were recorded after exposure. These herbicides reduced the number of adults that emerged from pupation (24–36%). Each herbicide has a different mode of action. Therefore, we speculate that effects are due to inert ingredients or indirect effects on food plant quality. If these herbicides act the same in A. mormo langei, they may contribute to the decline of this species. - Highlights: ► We evaluated the effects of three herbicides on the butterfly, Behr's metalmark. ► These herbicides are used to control invasive weeds in butterfly habitat. ► The herbicides reduced adult butterfly emergence. - Herbicides are used to remove invasive weeds from butterfly habitat. Certain herbicides may be having a negative effect on butterflies.

TBT-gehalten en effecten bij de Gewone Alikruik (Littorina littorea) en de Gevlochten Fuikhoorn (Nassarius reticulatus) langs de Nederlandse kust in 2009

NARCIS (Netherlands)

Kaag, N.H.B.M.; Jol, J.; Hoek-van Nieuwenhuizen, van M.

2009-01-01

Sinds 2005 analyseert IMARES het voorkomen van intersex bij Gewone Alikruiken (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met TBT vast te stellen.

Genetic syndromes in the family : child characteristics and parenting stress in Angelman, CHARGE, Cornelia de Lange, Prader-Willi, and Rett syndrome

NARCIS (Netherlands)

Wulffaert, Josette

2010-01-01

Aim of the dissertation: To expand the knowledge on the behavioural phenotypes, level of parenting stress and the relationship between child characteristics and parenting stress in five genetic syndromes. The included syndromes are Angelman, CHARGE, Cornelia de Lange, Prader-Willi, and Rett

Scanning Electron Microscope Studies of Interactions between Agaricus bisporus (Lang) Sing Hyphae and Bacteria in Casing Soil

OpenAIRE

Masaphy, Segula; Levanon, D.; Tchelet, R.; Henis, Y.

1987-01-01

Relationships between the hyphae of Agaricus bisporus (Lang) Sing and bacteria from the mushroom bed casing layer were examined with a scanning electron microscope. Hyphae growing in the casing layer differed morphologically from compost-grown hyphae. Whereas the compost contained thin single hyphae surrounded by calcium oxalate crystals, the casing layer contained mainly wide hyphae or mycelial strands without crystals. The bacterial population in the hyphal environment consisted of several ...

Jurassic-Paleogene intra-oceanic magmatic evolution of the Ankara Mélange, North-Central Anatolia, Turkey

Science.gov (United States)

Sarifakioglu, E.; Dilek, Y.; Sevin, M.

2013-11-01

Oceanic rocks in the Ankara Mélange along the Izmir-Ankara-Erzincan suture zone (IAESZ) in North-Central Anatolia include locally coherent ophiolite complexes (~179 Ma and ~80 Ma), seamount or oceanic plateau volcanic units with pelagic and reefal limestones (96.6 ± 1.8 Ma), metamorphic rocks with ages of 187.4 ± 3.7 Ma, 158.4 ± 4.2 Ma, and 83.5 ± 1.2 Ma, and subalkaline to alkaline volcanic and plutonic rocks of an island arc origin (~67-63 Ma). All but the arc rocks occur in a shaly-graywacke and/or serpentinite matrix, and are deformed by south-vergent thrust faults and folds that developed in the Middle to Late Eocene due to continental collisions in the region. Ophiolitic volcanic rocks have mid-ocean ridge (MORB) and island arc tholeiite (IAT) affinities showing moderate to significant LILE enrichment and depletion in Nb, Hf, Ti, Y and Yb, which indicate the influence of subduction-derived fluids in their melt evolution. Seamount/oceanic plateau basalts show ocean island basalt (OIB) affinities. The arc-related volcanic rocks, lamprophyric dikes and syeno-dioritic plutons exhibit high-K shoshonitic to medium-to high-K calc-alkaline compositions with strong enrichment in LILE, REE and Pb, and initial ϵNd values between +1.3 and +1.7. Subalkaline arc volcanic units occur in the northern part of the mélange, whereas the younger alkaline volcanic rocks and intrusions (lamprophyre dikes and syeno-dioritic plutons) in the southern part. The Early to Late Jurassic and Late Cretaceous epidote-actinolite, epidote-chlorite and epidote-glaucophane schists represent the metamorphic units formed in a subduction channel in the Northern Neotethys. The Middle to Upper Triassic neritic limestones spatially associated with the seamount volcanic rocks indicate that the Northern Neotethys was an open ocean with its MORB-type oceanic lithosphere by the Early Triassic. The Latest Cretaceous-Early Paleocene island arc volcanic, dike and plutonic rocks with

Jurassic-Paleogene intraoceanic magmatic evolution of the Ankara Mélange, north-central Anatolia, Turkey

Science.gov (United States)

Sarifakioglu, E.; Dilek, Y.; Sevin, M.

2014-02-01

Oceanic rocks in the Ankara Mélange along the Izmir-Ankara-Erzincan suture zone (IAESZ) in north-central Anatolia include locally coherent ophiolite complexes (∼ 179 Ma and ∼ 80 Ma), seamount or oceanic plateau volcanic units with pelagic and reefal limestones (96.6 ± 1.8 Ma), metamorphic rocks with ages of 256.9 ± 8.0 Ma, 187.4 ± 3.7 Ma, 158.4 ± 4.2 Ma, and 83.5 ± 1.2 Ma indicating northern Tethys during the late Paleozoic through Cretaceous, and subalkaline to alkaline volcanic and plutonic rocks of an island arc origin (∼ 67-63 Ma). All but the arc rocks occur in a shale-graywacke and/or serpentinite matrix, and are deformed by south-vergent thrust faults and folds that developed in the middle to late Eocene due to continental collisions in the region. Ophiolitic volcanic rocks have mid-ocean ridge (MORB) and island arc tholeiite (IAT) affinities showing moderate to significant large ion lithophile elements (LILE) enrichment and depletion in Nb, Hf, Ti, Y and Yb, which indicate the influence of subduction-derived fluids in their melt evolution. Seamount/oceanic plateau basalts show ocean island basalt (OIB) affinities. The arc-related volcanic rocks, lamprophyric dikes and syenodioritic plutons exhibit high-K shoshonitic to medium- to high-K calc-alkaline compositions with strong enrichment in LILE, rare earth elements (REE) and Pb, and initial ɛNd values between +1.3 and +1.7. Subalkaline arc volcanic units occur in the northern part of the mélange, whereas the younger alkaline volcanic rocks and intrusions (lamprophyre dikes and syenodioritic plutons) in the southern part. The late Permian, Early to Late Jurassic, and Late Cretaceous amphibole-epidote schist, epidote-actinolite, epidote-chlorite and epidote-glaucophane schists represent the metamorphic units formed in a subduction channel in the northern Neotethys. The Middle to Upper Triassic neritic limestones spatially associated with the seamount volcanic rocks indicate that the northern

TBT-gehalten en effecten bij de Gewone Alikruik (Littorina littorea) en de Gevlochten Fuikhoorn (Nassarius reticulatus) langs de Nederlandse kust in 2010

NARCIS (Netherlands)

Kaag, N.H.B.M.; Jol, J.G.; Hoek-van Nieuwenhuizen, van M.

2012-01-01

Sinds 2005 analyseert IMARES in opdracht van Rijkswaterstaat (RIKZ, later de Waterdienst) het voorkomen van intersex bij de Gewone Alikruik (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met

Epigenetic silencing of V(DJ recombination is a major determinant for selective differentiation of mucosal-associated invariant t cells from induced pluripotent stem cells.

Directory of Open Access Journals (Sweden)

Yutaka Saito

Full Text Available Mucosal-associated invariant T cells (MAITs are innate-like T cells that play a pivotal role in the host defense against infectious diseases, and are also implicated in autoimmune diseases, metabolic diseases, and cancer. Recent studies have shown that induced pluripotent stem cells (iPSCs derived from MAITs selectively redifferentiate into MAITs without altering their antigen specificity. Such a selective differentiation is a prerequisite for the use of MAITs in cell therapy and/or regenerative medicine. However, the molecular mechanisms underlying this phenomenon remain unclear. Here, we performed methylome and transcriptome analyses of MAITs during the course of differentiation from iPSCs. Our multi-omics analyses revealed that recombination-activating genes (RAG1 and RAG2 and DNA nucleotidylexotransferase (DNTT were highly methylated with their expression being repressed throughout differentiation. Since these genes are essential for V(DJ recombination of the T cell receptor (TCR locus, this indicates that nascent MAITs are kept from further rearrangement that may alter their antigen specificity. Importantly, we found that the repression of RAGs was assured in two layers: one by the modulation of transcription factors for RAGs, and the other by DNA methylation at the RAG loci. Together, our study provides a possible explanation for the unaltered antigen specificity in the selective differentiation of MAITs from iPSCs.

Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016

Science.gov (United States)

Kline, Antonie D.; Krantz, Ian D.; Deardorff, Matthew A.; Shirahige, Katsuhiko; Dorsett, Dale; Gerton, Jennifer L.; Wu, Meng; Mehta, Devanshi; Mills, Jason A.; Carrico, Cheri S.; Noon, Sarah; Herrera, Pamela S.; Horsfield, Julia A.; Bettale, Chiara; Morgan, Jeremy; Huisman, Sylvia A.; Moss, Jo; McCleery, Joseph; Grados, Marco; Hansen, Blake D.; Srivastava, Siddharth; Taylor-Snell, Emily; Kerr, Lynne M.; Katz, Olivia; Calof, Anne L.; Musio, Antonio; Egense, Alena; Haaland, Richard E.

2017-01-01

Cornelia de Lange Syndrome (CdLS) is due to mutations in the genes for the structural and regulatory proteins that make up the cohesin complex, and is considered a cohesinopathy disorder or, more recently, a transcriptomopathy. New phenotypes have been recognized in this expanding field. There are multiple clinical issues facing individuals with all forms of CdLS, particularly in the neurodevelopmental system, but also gastrointestinal, cardiac, and musculoskeletal. Aspects of developmental and cell biology have found common endpoints in the biology of the cohesin complex, with improved understanding of the mechanisms, easier diagnostic tests, and the possibility of potential therapeutics, all major clinical implications for the individual with CdLS. The following abstracts are the presentations from the 7th Cornelia de Lange Syndrome Scientific and Educational Symposium, June 22–23, 2016, in Orlando, FL, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting. In addition to the scientific and clinical discussions, there were talks related to practical aspects of behavior including autism, transitions, communication, access to medical care, and databases. At the end of the symposium, a panel was held, which included several parents, affected individuals and genetic counselors, and discussed the greatest challenges in life and how this information can assist in guiding future research. The Research Committee of the CdLS Foundation organizes this meeting, reviews, and accepts abstracts, and subsequently disseminates the information to the families through members of the Clinical Advisory Board and publications. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. PMID:28190301

Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016.

Science.gov (United States)

Kline, Antonie D; Krantz, Ian D; Deardorff, Matthew A; Shirahige, Katsuhiko; Dorsett, Dale; Gerton, Jennifer L; Wu, Meng; Mehta, Devanshi; Mills, Jason A; Carrico, Cheri S; Noon, Sarah; Herrera, Pamela S; Horsfield, Julia A; Bettale, Chiara; Morgan, Jeremy; Huisman, Sylvia A; Moss, Jo; McCleery, Joseph; Grados, Marco; Hansen, Blake D; Srivastava, Siddharth; Taylor-Snell, Emily; Kerr, Lynne M; Katz, Olivia; Calof, Anne L; Musio, Antonio; Egense, Alena; Haaland, Richard E

2017-05-01

Cornelia de Lange Syndrome (CdLS) is due to mutations in the genes for the structural and regulatory proteins that make up the cohesin complex, and is considered a cohesinopathy disorder or, more recently, a transcriptomopathy. New phenotypes have been recognized in this expanding field. There are multiple clinical issues facing individuals with all forms of CdLS, particularly in the neurodevelopmental system, but also gastrointestinal, cardiac, and musculoskeletal. Aspects of developmental and cell biology have found common endpoints in the biology of the cohesin complex, with improved understanding of the mechanisms, easier diagnostic tests, and the possibility of potential therapeutics, all major clinical implications for the individual with CdLS. The following abstracts are the presentations from the 7th Cornelia de Lange Syndrome Scientific and Educational Symposium, June 22-23, 2016, in Orlando, FL, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting. In addition to the scientific and clinical discussions, there were talks related to practical aspects of behavior including autism, transitions, communication, access to medical care, and databases. At the end of the symposium, a panel was held, which included several parents, affected individuals and genetic counselors, and discussed the greatest challenges in life and how this information can assist in guiding future research. The Research Committee of the CdLS Foundation organizes this meeting, reviews, and accepts abstracts, and subsequently disseminates the information to the families through members of the Clinical Advisory Board and publications. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. © 2017 Wiley Periodicals, Inc.

Structural context and variation of ocean plate stratigraphy, Franciscan Complex, California: insight into mélange origins and subduction-accretion processes

Science.gov (United States)

Wakabayashi, John

2017-12-01

The transfer (accretion) of materials from a subducting oceanic plate to a subduction-accretionary complex has produced rock assemblages recording the history of the subducted oceanic plate from formation to arrival at the trench. These rock assemblages, comprising oceanic igneous rocks progressively overlain by pelagic sedimentary rocks (chert and/or limestone) and trench-fill clastic sedimentary rocks (mostly sandstone, shale/mudstone), have been called ocean plate stratigraphy (OPS). During accretion of OPS, megathrust slip is accommodated by imbricate faults and penetrative strain, shortening the unit and leading to tectonic repetition of the OPS sequence, whereas OPS accreted at different times are separated by non-accretionary megathrust horizons. The Franciscan subduction complex of California accreted episodically over a period of over 150 million years and incorporated OPS units with a variety of characteristics separated by non-accretionary megathrust horizons. Most Franciscan OPS comprises MORB (mid-ocean-ridge basalt) progressively overlain by chert and trench-fill clastic sedimentary rocks that are composed of variable proportions of turbidites and siliciclastic and serpentinite-matrix olistostromes (sedimentary mélanges). Volumetrically, the trench-fill component predominates in most Franciscan OPS, but some units have a significant component of igneous and pelagic rocks. Ocean island basalt (OIB) overlain by limestone is less common than MORB-chert assemblages, as are abyssal serpentinized peridotite slabs. The earliest accreted OPS comprises metabasite of supra-subduction zone affinity imbricated with smaller amounts of metaultramafic rocks and metachert, but lacking a clastic component. Most deformation of Franciscan OPS is localized along discrete faults rather than being distributed in the form of penetrative strain. This deformation locally results in block-in-matrix tectonic mélanges, in contrast to the sedimentary mélanges making up part of

El cine de Fritz Lang. Influencia de los mitos y arquetipos en su filmografía

OpenAIRE

LÓPEZ HERREROS, ANDRÉS

2013-01-01

El siguiente proyecto presenta un estudio personalizado de la obra cinematográfica del cineasta austríaco Fritz Lang para analizar sus tendencias y vincular los arquetipos a sus películas, principalmente las ideas planteadas por los psicólogos Segmund Freud y Carl Gustav Jung referente a las ideas primarias y secundarias. Para ello se muestra la influencia de la mitología en su narrativa cinematográfica, la presencia de arquetipos y elementos propios del subconsciente colectivo en su cine así...

Mucosal-Associated Invariant T Cells: New Insights into Antigen Recognition and Activation

Directory of Open Access Journals (Sweden)

Xingxing Xiao

2017-11-01

Full Text Available Mucosal-associated invariant T (MAIT cells, a novel subpopulation of innate-like T cells that express an invariant T cell receptor (TCRα chain and a diverse TCRβ chain, can recognize a distinct set of small molecules, vitamin B metabolites, derived from some bacteria, fungi but not viruses, in the context of an evolutionarily conserved major histocompatibility complex-related molecule 1 (MR1. This implies that MAIT cells may play unique and important roles in host immunity. Although viral antigens are not recognized by this limited TCR repertoire, MAIT cells are known to be activated in a TCR-independent mechanism during some viral infections, such as hepatitis C virus and influenza virus. In this article, we will review recent works in MAIT cell antigen recognition, activation and the role MAIT cells may play in the process of bacterial and viral infections and pathogenesis of non-infectious diseases.

Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016

NARCIS (Netherlands)

Kline, Antonie D.; Krantz, Ian D.; Deardorff, Matthew A.; Shirahige, Katsuhiko; Dorsett, Dale; Gerton, Jennifer L.; Wu, Meng; Mehta, Devanshi; Mills, Jason A.; Carrico, Cheri S.; Noon, Sarah; Herrera, Pamela S.; Horsfield, Julia A.; Bettale, Chiara; Morgan, Jeremy; Huisman, Sylvia A.; Moss, Jo; McCleery, Joseph; Grados, Marco; Hansen, Blake D.; Srivastava, Siddharth; Taylor-Snell, Emily; Kerr, Lynne M.; Katz, Olivia; Calof, Anne L.; Musio, Antonio; Egense, Alena; Haaland, Richard E.

2017-01-01

Cornelia de Lange Syndrome (CdLS) is due to mutations in the genes for the structural and regulatory proteins that make up the cohesin complex, and is considered a cohesinopathy disorder or, more recently, a transcriptomopathy. New phenotypes have been recognized in this expanding field. There are

Research in action: from AIDS to global health to impact. A symposium in recognition of the scientific contributions of Professor Joep Lange

NARCIS (Netherlands)

Boender, T. Sonia; Barré-Sinoussi, Françoise; Cooper, David; Goosby, Eric; Hankins, Catherine; Heidenrijk, Michiel; de Jong, Menno; Kazatchkine, Michel; Laoye, Fola; Merson, Michael; Reiss, Peter; Rinke de Wit, Tobias F.; Rogo, Khama; Schellekens, Onno; Schultsz, Constance; Sigaloff, Kim C. E.; Simon, John; Zewdie, Debrework

2015-01-01

On Tuesday 14 October 2014, 850 family members, friends, colleagues, prominent scientists and dignitaries from all over the world gathered in Amsterdam to pay tribute to the lives and legacies of Joep Lange and Jacqueline van Tongeren. The remembrance was held at the Amsterdam Medical Centre (AMC)

Successful Growth Hormone Therapy in Cornelia de Lange Syndrome.

Science.gov (United States)

de Graaf, Michael; Kant, Sarina G; Wit, Jan Maarten; Willem Redeker, Egbert Johan; Eduard Santen, Gijs Willem; Henriëtta Verkerk, Annemieke Johanna Maria; Uitterlinden, André Gerardus; Losekoot, Monique; Oostdijk, Wilma

2017-12-15

Cornelia de Lange syndrome (CdLS) is a both clinically and genetically heterogeneous syndrome. In its classical form, it is characterised by distinctive facial features, intra-uterine growth retardation, short stature, developmental delay, and anomalies in multiple organ systems. NIPBL, SMC1A, SMC3, RAD21 and HDAC8, all involved in the cohesin pathway, have been identified to cause CdLS. Growth hormone (GH) secretion has been reported as normal, and to our knowledge, there are no reports on the effect of recombinant human GH treatment in CdLS patients. We present a patient born small for gestational age with persistent severe growth retardation [height -3.4 standard deviation score (SDS)] and mild dysmorphic features, who was treated with GH from 4.3 years of age onward and was diagnosed 6 years later with CdLS using whole-exome sequencing. Treatment led to a height gain of 1.6 SDS over 8 years. Treatment was interrupted shortly due to high serum insulin-like growth factor-1 serum values. In conclusion, GH therapy may be effective and safe for short children with CdLS.

Mucosal-Associated Invariant T Cell Interactions with Commensal and Pathogenic Bacteria: Potential Role in Antimicrobial Immunity in the Child

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Liana Ghazarian

2017-12-01

Full Text Available Mucosal-associated invariant T (MAIT cells are unconventional CD3+CD161high T lymphocytes that recognize vitamin B2 (riboflavin biosynthesis precursor derivatives presented by the MHC-I related protein, MR1. In humans, their T cell receptor is composed of a Vα7.2-Jα33/20/12 chain, combined with a restricted set of Vβ chains. MAIT cells are very abundant in the liver (up to 40% of resident T cells and in mucosal tissues, such as the lung and gut. In adult peripheral blood, they represent up to 10% of circulating T cells, whereas they are very few in cord blood. This large number of MAIT cells in the adult likely results from their gradual expansion with age following repeated encounters with riboflavin-producing microbes. Upon recognition of MR1 ligands, MAIT cells have the capacity to rapidly eliminate bacterially infected cells through the production of inflammatory cytokines (IFNγ, TNFα, and IL-17 and cytotoxic effector molecules (perforin and granzyme B. Thus, MAIT cells may play a crucial role in antimicrobial defense, in particular at mucosal sites. In addition, MAIT cells have been implicated in diseases of non-microbial etiology, including autoimmunity and other inflammatory diseases. Although their participation in various clinical settings has received increased attention in adults, data in children are scarce. Due to their innate-like characteristics, MAIT cells might be particularly important to control microbial infections in the young age, when long-term protective adaptive immunity is not fully developed. Herein, we review the data showing how MAIT cells may control microbial infections and how they discriminate pathogens from commensals, with a focus on models relevant for childhood infections.

Planeerimine Fordi nimel / Aet Annist

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Annist, Aet

2007-01-01

Püüe muuta planeerimisega inimeste käitumist on sageli juba ette läbikukkumisele määratud. Näiteks toodud 1960. aastatel rajatud Milton Keynesi rattateede võrgustikuga aedlinn, kus elanikud kasutavad peamiselt autosid, nõukogude võimu ajal püstitatud köögita elamud, Rio de Janeiro slummielanikele isetekkeliste hüttide asemele püstitatud korterelamud, kus elamistingimused halvenesid

Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?

Science.gov (United States)

Haeryfar, S M Mansour; Shaler, Christopher R; Rudak, Patrick T

2018-02-22

Mucosa-associated invariant T (MAIT) cells are a subset of innate-like T lymphocytes known for their ability to respond to MHC-related protein 1 (MR1)-restricted stimuli and select cytokine signals. They are abundant in humans and especially enriched in mucosal layers, common sites of neoplastic transformation. MAIT cells have been found within primary and metastatic tumors. However, whether they promote malignancy or contribute to anticancer immunity is unclear. On the one hand, MAIT cells produce IL-17A in certain locations and under certain circumstances, which could in turn facilitate neoangiogenesis, intratumoral accumulation of immunosuppressive cell populations, and cancer progression. On the other hand, they can express a potent arsenal of cytotoxic effector molecules, NKG2D and IFN-γ, all of which have established roles in cancer immune surveillance. In this review, we highlight MAIT cells' characteristics as they might pertain to cancer initiation, progression, or control. We discuss recent findings, including our own, that link MAIT cells to cancer, with a focus on colorectal carcinoma, as well as some of the outstanding questions in this active area of research. Finally, we provide a hypothetical picture in which MAIT cells constitute attractive targets in cancer immunotherapy.

Intra-Hepatic Depletion of Mucosal-Associated Invariant T Cells in Hepatitis C Virus-Induced Liver Inflammation.

Science.gov (United States)

Bolte, Fabian J; O'Keefe, Ashley C; Webb, Lauren M; Serti, Elisavet; Rivera, Elenita; Liang, T Jake; Ghany, Marc; Rehermann, Barbara

2017-11-01

Chronic hepatitis affects phenotypes of innate and adaptive immune cells. Mucosal-associated invariant T (MAIT) cells are enriched in the liver as compared with the blood, respond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated from the gut. Little is known about the role of MAIT cells in livers of patients with chronic hepatitis C virus (HCV) infection and their fate after antiviral therapy. We collected blood samples from 42 patients with chronic HCV infection who achieved a sustained virologic response after 12 weeks of treatment with sofosbuvir and velpatasvir. Mononuclear cells were isolated from blood before treatment, at weeks 4 and 12 during treatment, and 24 weeks after the end of treatment. Liver biopsies were collected from 37 of the patients prior to and at week 4 of treatment. Mononuclear cells from 56 blood donors and 10 livers that were not suitable for transplantation were used as controls. Liver samples were assessed histologically for inflammation and fibrosis. Mononuclear cells from liver and blood were studied by flow cytometry and analyzed for responses to cytokine and bacterial stimulation. The frequency of MAIT cells among T cells was significantly lower in blood and liver samples of patients with HCV infection than of controls (median, 1.31% vs 2.32% for blood samples, P = .0048; and median, 4.34% vs 13.40% for liver samples, P = .001). There was an inverse correlation between the frequency of MAIT cells in the liver and histologically determined levels of liver inflammation (r = -.5437, P = .0006) and fibrosis (r = -.5829, P = .0002). MAIT cells from the liver had higher levels of activation and cytotoxicity than MAIT cells from blood (P liver inflammation and MAIT cell activation and cytotoxicity, and increased the MAIT cell frequency among intra-hepatic but not blood T cells. The MAIT cell response to T-cell receptor-mediated stimulation did not change during the 12 weeks of

Efficiency of the application of an increasing hydrogel dose in bispore mushrooms cultivation. Agaricus bisporus (Lange Sing. Imbach

Directory of Open Access Journals (Sweden)

Grzegorz Koc

2011-01-01

Full Text Available The economical efficiency of the application of an increasing hydrogel dose in bispore mushrooms (Agaricus bisporus (Lange Sing. Imbach SYLVAN 737 has been experimented in controlled weather conditions. It was found that the application of a 50 and 150 g•m-2 hydrogel dose is not economically proved due to the lack of harvest significant increase. In the cultivation of this particular variety of mushrooms, the optimal hydrogel dose should not be 100 g•m-2 of subsoil.

Scanning Electron Microscope Studies of Interactions between Agaricus bisporus (Lang) Sing Hyphae and Bacteria in Casing Soil

Science.gov (United States)

Masaphy, Segula; Levanon, D.; Tchelet, R.; Henis, Y.

1987-01-01

Relationships between the hyphae of Agaricus bisporus (Lang) Sing and bacteria from the mushroom bed casing layer were examined with a scanning electron microscope. Hyphae growing in the casing layer differed morphologically from compost-grown hyphae. Whereas the compost contained thin single hyphae surrounded by calcium oxalate crystals, the casing layer contained mainly wide hyphae or mycelial strands without crystals. The bacterial population in the hyphal environment consisted of several types, some attached to the hyphae with filamentlike structures. This attachment may be important in stimulation of pinhead initiation. Images PMID:16347340

En rask eller lang og kronglete vei til topps? Næringslivslederes karriereforløp

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Trygve Gulbrandsen

2018-01-01

Full Text Available Det er mange studier av den sosiale bakgrunnen til toppledere i næringslivet. Et tema som har fått mindre oppmerksomhet, er hvor lang tid det tok for lederne å nå til topps. En skulle forvente at ledere med bakgrunn fra alminnelige kår brukte lenger tid opp til sine topposisjoner enn kolleger fra de øverste sosiale lag. Analysene i denne artikkelen viser imidlertid at dette ikke stemmer. Toppledere i norsk næringsliv med fedre hjemmehørende i arbeiderklassen trengte ikke flere år på å bli toppledere enn ledere med fedre som tilhørte overklassen. Derimot viser det seg at jo høyere utdanning mor hadde, desto raskere karriere hadde topplederne.

NOAA TIFF Image - Backscatter - Lang Bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This geotiff represents a 1 meter resolution backscatter mosaic of the reef shelf and the steep slopes of the Lang Bank (H12639) of St. Croix, US Virgin Islands. The...

Zgaga, P., Teichler, U., & Brennan, J. (Eds.) (2012). The globalisation challenge for European higher education / Convergence and Diversity, Centres and Peripheries. Frankfurt/M.: Peter Lang. [Book review

OpenAIRE

Strajn, Darko

2013-01-01

Book review of: Zgaga, P., Teichler, U., & Brennan, J. (Eds.) (2012). The globalisation challenge for European higher education / Convergence and Diversity, Centres and Peripheries. Frankfurt/M.: Peter Lang. 389 pp., ISBN 978-3-631- 6398-5.

Rapport om kystsikringsforsøg ved anvendelse af lodrette drænrør langs Hjørring Kommunes kyststrækning

DEFF Research Database (Denmark)

Burcharth, Hans F.

Med økonomisk støtte fra Erhversfremmestyrelsen har Hjørring Kommune i samarbejde med Skagen Innovationscenter, SIC, gennemført et kystsikringsforsøg med anvendelse af lodrette drænrør over en 3.7 km lang kyststraekning fra Skallerup Klit ti1 Nørlev nord. Strækningen er stationeret St. 0,0 - St 3...

NOAA TIFF Image - Bathymetry - Lang bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a 1 meter resolution bathymetry of the reef shelf and the steep slopes of Lang Bank (H12639) of St. Croix, US Virgin Islands. The M-I907-NF-14...

Ühe novelli lugu : subjektiivne kirjanduslooline etüüd / Aivar Kull

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Kull, Aivar, 1955-

2015-01-01

Mait Metsanurga pikemast novellist "Dora Praats", mis ilmus 1943. a. vene keeles; avaldatud ka 16-osalise järjejutuna Toronto ajalehes "Vaba Eestlane" (8. veebr. - 2. aprill 1958) ning Mait Metsanurga novellikogumikus "Kreeps" (Tallinn : Eesti Raamat, 2005)

[Lange, Thomas. Zwischen Reformation und Untergang Alt-Livlands. Der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer] / Madis Maasing

Index Scriptorium Estoniae

Maasing, Madis, 1984-

2014-01-01

Arvustus: Lange, Thomas. Zwischen Reformation und Untergang Alt-Livlands. Der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer

Utilisation de mélanges non-azéotropiques dans les cycles thermodynamiques à compression Use of Non-Azeotropic Mixtures in Thermodynamic Compression Cycles

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Ambrosino J. L.

2006-11-01

Full Text Available L'utilisation de mélanges non-azéotropiques comme fluides frigorigènes présente différents avantages en ce qui concerne le fonctionnement des installations de réfrigération / conditionnement / chauffage mettant en oeuvre des cycles thermodynamiques à compression avec changement de phase. En outre, de tels mélanges représentent une alternative intéressante aux corps purs actuellement recherchés pour résoudre les problèmes d'environnement liés à la destruction de la couche d'ozone. Cet article analyse les connaissances acquises concernant la mise en oeuvre d'une telle solution. The use of non-azeotropic mixtures as refrigerants has various advantages concerning the operating of refrigeration / air-conditioning / heating installations implementing thermodynamic compression cycles with a phase change. Likewise, such mixtures represent an interesting alternative to pure components which are now being looked to as a solution to environmental problems linked to the destruction of the ozone layer. This article analyzes what is known about the implementation of such a solution.

Reflections on 35 years with Applied Optics: outgoing editorial.

Science.gov (United States)

Mait, Joseph N

2014-10-20

Applied Optics' Editor-in-Chief, Joseph N. Mait reflects on his experience as a reader, author, reviewer and eventual editor of the journal. Dr. Mait also introduces the incoming Editor-in-Chief, Ronald G. Driggers and acknowledges outgoing Division Editor, T.-C. Poon.

Listwaenite in the Sartohay ophiolitic mélange (Xinjiang, China): A genetic model based on petrology, U-Pb chronology and trace element geochemistry

Science.gov (United States)

Qiu, Tian; Zhu, Yongfeng

2018-03-01

Listwaenite lenses in the Sartohay ophiolitic mélange (Xinjiang, China) were formed via reactions between serpentinite and metasomatic fluids. First, serpentinite changed into talc schist via the reaction of serpentine + CO2 → talc + magnesite + H2O. Second, talc schist changed into listwaenite via the reaction of talc + CO2 → magnesite + quartz + H2O. Magnetite was progressively destroyed during transformation from serpentinite to talc schist, and completely consumed in listwaenite. Zircon crystals 30-100 μm long, disseminating in talc schist, undeformed listwaenite and mylonitized listwaenite, coexist with talc, quartz and magnesite, while micron-sized zircon grains (ages (302.9 ± 6.8 Ma, 299.7 ± 5.5 Ma and 296.5 ± 3.5 Ma), and are thought to represent the age of formation of the talc schist and listwaenite. These ages are indistinguishable within errors and suggest a rapid transformation from talc schist to listwaenite. Some zircon rims in samples of the undeformed listwaenite and mylonitized listwaenite give much younger apparent U-Pb ages (280-277 Ma), which could be interpreted as a recrystallization age reflecting late-stage shearing in the Sartohay ophiolitic mélange.

Connected Gene Communities Underlie Transcriptional Changes in Cornelia de Lange Syndrome.

Science.gov (United States)

Boudaoud, Imène; Fournier, Éric; Baguette, Audrey; Vallée, Maxime; Lamaze, Fabien C; Droit, Arnaud; Bilodeau, Steve

2017-09-01

Cornelia de Lange syndrome (CdLS) is a complex multisystem developmental disorder caused by mutations in cohesin subunits and regulators. While its precise molecular mechanisms are not well defined, they point toward a global deregulation of the transcriptional gene expression program. Cohesin is associated with the boundaries of chromosome domains and with enhancer and promoter regions connecting the three-dimensional genome organization with transcriptional regulation. Here, we show that connected gene communities, structures emerging from the interactions of noncoding regulatory elements and genes in the three-dimensional chromosomal space, provide a molecular explanation for the pathoetiology of CdLS associated with mutations in the cohesin-loading factor NIPBL and the cohesin subunit SMC1A NIPBL and cohesin are important constituents of connected gene communities that are centrally positioned at noncoding regulatory elements. Accordingly, genes deregulated in CdLS are positioned within reach of NIPBL- and cohesin-occupied regions through promoter-promoter interactions. Our findings suggest a dynamic model where NIPBL loads cohesin to connect genes in communities, offering an explanation for the gene expression deregulation in the CdLS. Copyright © 2017 by the Genetics Society of America.

Mechanisms and processes of stratal disruption and mixing in the development of melanges and broken formations: Redefining and classifying melanges : Redefining and classifying mélanges

NARCIS (Netherlands)

Festa, A.; Dilek, Yildirim; Pini, Gian Andrea; Codegone, Giulia; Ogata, K.

2012-01-01

The terms mélange and broken formation have been used in different ways in the literature. The lack of agreement on their definition often leads to confusion and misinterpretations. An evaluation of the various uses of these terms allows us to consider several types of chaotic rock bodies originated

NOAA TIFF Image - Backscatter - Lang Bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83 (NCEI Accession 0128255)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This geotiff represents a 1 meter resolution backscatter mosaic of the reef shelf and the steep slopes of the Lang Bank (H12639) of St. Croix, US Virgin Islands. The...

Punaste õhtute purpur / Jüri Annist

Index Scriptorium Estoniae

Annist, Jüri, 1950-

2015-01-01

Punane tamm, punane vaher, jaapani juudapuulehik, äädikapuu, pihlaka Sorbus sort 'Dodong' ja tiivulise kikkapuu sort 'Compactus' värvuvad sügisel kaunilt punaseks. Autori arvates on kõige punasem sügisvärvus tiivulisel kikkapuul 'Compactus'

Mõõdulindiga õnne ja edu kallal / Anneli Aasmäe

Index Scriptorium Estoniae

Aasmäe, Anneli, 1973-

2000-01-01

Juhtimiskonsultant Mait Raava kinnitusel on edukus 70 protsenti kaasasündinud omadus, Eesti edukatel on tegutsemisvajadus veres, nad võivad toetuda Iisraeli päritolu juhtimisteoreetiku Eliyahu M. Goldratti õpetusele, mitte eduretsepte ja õnnevalemeid pakkuvaile autorite rivile Dale Carnegie'st Ben Furmanini. Kommentaarid: Aune Past, Mait Raava

Pompe de chaleur fonctionnant avec un mélange de fluides Heat Pump Operating with a Fluid Mixture

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Vidal J.

2006-11-01

Full Text Available Lorsqu'une pompe de chaleur échange de la chaleur avec des fluides extérieurs, dont la température évolue au cours de l'échange, il est possible d'augmenter le coefficient de performance en utilisant comme fluide de travail un mélange non-azéotropique qui se vaporise et se condense suivant une évolution de température parallèle à celle du fluide extérieur avec lequel s'effectue cet échange. L'utilisation de mélanges dans les pompes de chaleur a été étudiée, d'une part, au moyen de modèles de simulation sur ordinateur et, d'autre part, au moyen d'essais expérimentaux. Différentes applications ont été examinées à la fois dans le domaine du chauffage résidentiel et dans le domaine industriel. Whenever heat is recovered and delivered, the coefficient of performance of a heat pump can be increased by using a fluid mixture selected to have a temperature variation, during the vaporization and condensation stages, parallel to that of the outside fluid with which the heat exchange takes place. Such a solution was investigated both theoretically and experimentally. It has been shown that significant savings can be expected, ranging up to 50% of the energy consumption of conventional heat pumps in some cases. Various applications for home and industrial heating have been examined, and the economic prospects have been found to be satisfactory. Further work is needed to develop such heat pumps on a commercial basis.

Crescimento de Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae sob diferentes níveis de sombreamento Growth of Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae under different shading levels

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Ana Lúcia da Silva Lima

2010-03-01

Full Text Available Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. é uma espécie clímax tolerante a sombra, ao passo que Enterolobium contortisiliquum (Vell. Morong. é uma espécie pioneira. O desenvolvimento destas espécies pode refletir a habilidade de adaptação aos diferentes fatores ambientais (luz, água e temperatura no local em que estão crescendo. O suprimento inadequado de um desses fatores pode reduzir o vigor da planta e limitar seu desenvolvimento. O presente trabalho teve como objetivo avaliar os efeitos do nível de sombreamento no crescimento e a concentração de pigmentos fotossintéticos em duas espécies de leguminosas arbóreas, Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong. O experimento foi conduzido no Setor de Olericultura do Centro Universitário Luterano de Ji-Paraná (CEULJI/ULBRA/Rondônia. Durante a formação das mudas, ambas as espécies foram expostas a quatro tratamentos de sombra: 0 % (controle - sol pleno; 30 %; 50 % e 80 %. Cada tratamento foi constituído com três repetições de cada espécie; o delineamento experimental foi inteiramente casualisado. Quatro meses após a semeadura, as seguintes análises foram realizadas: número de folhas, altura da planta, comprimento do sistema radicular, massa seca total e concentração de pigmentos fotossintéticos. O tratamento sob sol pleno afetou negativamente o crescimento de ambas as espécies. As mudas crescidas sob 50% e 80% apresentaram melhor desenvolvimento. Conforme o aumento do sombreamento houve um decréscimo na razão clorofila a/b e um aumento nas concentrações de clorofila total e carotenóides totais.Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. is a clímax shadow tolerant specie and Enterolobium contortisiliquum (Vell. Morong., by the other hand, is considered as a pioneer specie. The development of these species may reflect its adaptation ability to different environmental

NOAA TIFF Image - Bathymetry - Lang bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83 (NCEI Accession 0128255)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a 1 meter resolution bathymetry of the reef shelf and the steep slopes of Lang Bank (H12639) of St. Croix, US Virgin Islands. The M-I907-NF-14...

25 kaadrit sekundis / Liis Auväärt

Index Scriptorium Estoniae

Auväärt, Liis

2009-01-01

Nukufilmis käib töö filmiga "Lisa Limone & Maroc Orange", režissöör Mait Laas, animaatorid Triin Sarapik-Kivi, Märt Kivi, operaator Ragnar Neljandi, nukumeistrid Heigo Eeriksoo, Taivo Müürsep, Ene Mellow ja Kreeta Käeri. Dekoratsioonimeistrid Mait Erik ja Roman Kuznetsov

[Thomas Lange. Zwischen Reformation und Untergang Alt-Livlands : der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer] / Juhan Kreem

Index Scriptorium Estoniae

Kreem, Juhan, 1971-

2015-01-01

Arvustus: Lange, Thomas. Zwischen Reformation und Untergang Alt-Livlands : der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer (Hamburger Beiträge zur Geschichte des östlichen Europa)

Märt Agu: "Isa vari käib mul kogu aeg kannul" / Märt Agu ; interv. Aigi Viira

Index Scriptorium Estoniae

Agu, Märt

2006-01-01

1. okt. tähistas oma 30-aastast sünnipäeva ja oma ellukutsuja Mait Agu 55-sünniaastapäeva Tallinna Ülikooli koreograafiaosakond. Sel puhul esitati Estonias Mait Agu tantsulavastus "Kodalased ja kaasaegsed", mille seadis uuesti lavale Märt Agu oma isa loodud koreograafia põhjal

The Travails of Criticality: Understanding Peter McLaren's Revolutionary Vocation. An Article Review of Peter McLaren, "Pedagogy of Insurrection" (New York: Peter Lang, 2015)

Science.gov (United States)

Baldacchino, John

2017-01-01

This is an article review of Peter McLaren's "Pedagogy of Insurrection" (New York: Peter Lang, 2015). While it seeks to position McLaren's work within the context of critical pedagogy, this paper also assesses McLaren from the wider discussion of Marxist--Hegelian discourse as it evolved within the Left. Engaging with McLaren critically,…

Plutonic rocks in the Mineoka-Setogawa ophiolitic mélange, central Japan: Fragments of middle to lower crust of the Izu-Bonin-Mariana Arc?

Science.gov (United States)

Ichiyama, Yuji; Ito, Hisatoshi; Hokanishi, Natsumi; Tamura, Akihiro; Arai, Shoji

2017-06-01

A Paleogene accretionary complex, the Mineoka-Setogawa Belt, is distributed around the Izu Collision Zone, central Japan. Plutonic rocks of gabbro, diorite and tonalite compositions are included as fragments and dykes in an ophiolitic mélange in this belt. Zircon U-Pb dating of the plutonic rocks indicates that they were formed at ca. 35 Ma simultaneously. These ages are consistent with Eocene-Oligocene tholeiite and calc-alkaline arc magmatism in the Izu-Bonin-Mariana (IBM) Arc and exclude several previous models for the origin of the Mineoka-Setogawa ophiolitic rocks. The geochemical characteristics of these plutonic rocks are similar to those of the Eocene-Oligocene IBM tholeiite and calc-alkaline volcanic rocks as well as to the accreted middle crust of the IBM Arc, the Tanzawa Plutonic Complex. Moreover, their lithology is consistent with those of the middle and lower crust of the IBM Arc estimated from the seismic velocity structure. These lines of evidence strongly indicate that the plutonic rocks in the Mineoka-Setogawa ophiolitic mélange are fragments of the middle to lower crust of the IBM Arc. Additionally, the presence of the Mineoka-Setogawa intermediate to felsic plutonic rocks supports the hypothesis that intermediate magma can form continental crust in intra-oceanic arcs.

Characterization of single spore isolates of Agaricus bisporus (Lange) Imbach using conventional and molecular methods.

Science.gov (United States)

Sharma, Manju; Suman, B C; Gupta, Dharmesh

2014-10-01

Strains A-15, S11, S-140, and U3 of Agaricus bisporus (Lange) Imbach, were used as parent strains for raising single spore homokaryotic isolates. Out of total 1,642 single spore isolates, only 36 single spore isolates were homokaryons and exhibited slow mycelial growth rate (≤2.0 mm/day) and appressed colony morphology. All these SSIs failed to produce pinheads in Petri plates even after 65 days of incubation, whereas the strandy slow growing SSIs along with parent strains were able to form the fructification in petriplates after 30 days. Out of 24, six ISSR primers, exhibited scorable bands. In the ISSR fingerprints, single spore isolates, homokaryons, lacked amplification products at multiple loci; they grow slowly and all of them had appressed types of colony morphology. The study revealed losses of ISSR polymorphic patterns in non-fertile homokaryotic single spore isolates compared to the parental control or fertile heterokaryotic single spore isolates.

Cochlear implantation in children with Jervell and Lange-Nielsen syndrome - a cautionary tale.

Science.gov (United States)

Broomfield, Stephen J; Bruce, Iain A; Henderson, Lise; Ramsden, Richard T; Green, Kevin M J

2012-08-01

Jervell and Lange-Nielsen (JLN) syndrome is a rare cause of congenital profound hearing loss associated with a prolonged QT interval on the electrocardiogram. Children presenting for cochlear implantation with this condition may be asymptomatic but are at risk of sudden death. SCREENING AND SUBSEQUENT: careful management is therefore required to ensure a successful outcome. We present our experience of cochlear implantation in children with JLN syndrome, including two who died unexpectedly, and suggest a protocol for management of such cases. Clinical presentation Four cases of cochlear implantation in JLN syndrome are described. None had any previous cardiological family history. Two were diagnosed pre-operatively but, despite appropriate management under a cardiologist, died from cardiac arrest; the first in the perioperative period following reimplantation for infection, and the second unrelated to his cochlear implant surgery. The other two patients were diagnosed only subsequent to their implantation and continue to use their implants successfully. These cases highlight the variation in presentation of JLN syndrome, and the spectrum of disease severity that exists. Our protocol stresses the importance of careful assessment and counselling of parents by an experienced implant team.

Concomitant posterior hip dislocation, ipsilateral intertrochanteric- and proximal tibial- fractures with popliteal artery injury: a challenging trauma mélange

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Pranit N. Chotai

2015-12-01

Full Text Available Constellation of ipsilateral posterior hip dislocation, intertrochanteric- and proximal tibial fracture with popliteal artery injury is rare. Management of this presentation is challenging. A motor vehicle accident victim presented with these injuries, but without any initial signs of vascular compromise. Popliteal artery injury was diagnosed intra-operatively and repaired. This was followed by external fixation of tibial fracture, open reduction of dislocated hip and internal fixation of intertrochanteric fracture. Patient regained bilateral complete weight bearing and returned to pre-accident activity level. Apt surgical management including early repair of vascular injury in such a trauma mélange allows for a positive postoperative outcome.

Repensar la criminología con Luhmann, Lang, Foucault

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Luciano Nuzzo

2013-01-01

Full Text Available El tema que el artículo afronta es: ¿cuál es el objeto de la criminología? Para responder a esta pregunta es necesario analizar el estatuto epistemológico delsaber criminológico. Pero si se busca una respuesta a este problema dentro del debate criminológico, se quedará desilusionado. La criminología parece no darse plenamente cuenta de la necesidad de un método capaz de hacer posible una comprensión de su propio objeto. El autor propone seguir tres caminosque, desde perspectivas diferentes, afrontan el problema fundamental para cada observación social, es decir, el hecho de que cada observación de la sociedad es parte de lo que se quiere describir. El primer recorrido propuesto es la teoría de los sistemas sociales de Niklas Luhmann. Mediante la distinción entre observación de primer y de segundo orden es posible comprender el problema del objeto sin caer en la paradoja de la autoimplicación. El segundo recorrido propuesto es una obra de arte y precisamente el film de Frit Lang M., El monstruo de Dusseldorf. El arte, en efecto, permite ver lo que no podemos ver dentro de los confines de una observación científica. El arte permite rodear el punto ciego de la propia observación. Por último, el tercer recorrido propuesto al lector es la genealogía del poder descrita por Michel Foucault en el curso al College de France de 1974-1975, dedicado a los Anormales Estos tres recorridos permiten comprender desde perspectivas diferentes que la criminología no podrá producir conocimientos suficientemente adecuados a su objeto si no comprende cómo ella misma está siempre implicada en la construcción del objeto que observa.

A Comparison of Documentary Approaches: Margaret Bourke-White and Erskine Caldwell, Authors of "You Have Seen Their Faces," and Dorothea Lange and Paul S. Taylor, Authors of "An American Exodus."

Science.gov (United States)

Hanson, Art

Two books that use documentary photography to examine social problems--"You Have Seen Their Faces," a 1937 study of Southern sharecroppers by Margaret Bourke-White and Erskine Caldwell, and "An American Exodus," a 1939 examination of the migration of farm families by Dorothea Lange and Paul S. Taylor--are compared in this…

Evaluation of Butanol–Gasoline Blends in a Port Fuel-injection, Spark-Ignition Engine Évaluation de mélange butanol-essence dans un moteur à allumage commandé à injection indirecte

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Dernotte J.

2009-11-01

Full Text Available This paper assesses different butanol–gasoline blends used in a port fuel-injection, spark-ignition engine to quantify the influence of butanol addition on the emission of unburned hydrocarbons, carbon monoxide, and nitrogen oxide. Furthermore, in-cylinder pressure was measured to quantify combustion stability and to compare the ignition delay and fully developed turbulent combustion phases as given by 0%–10% and 10%–90% Mass Fraction Burned (MFB. The main findings are: 1 a 40% butanol/60% gasoline blend by volume (B40 minimizes HC emissions; 2 no significant change in NOx emissions were observed, with the exception of the 80% butanol/20% gasoline blend; 3 the addition of butanol improves combustion stability as measured by the COV of IMEP; 4 butanol added to gasoline reduces ignition delay (0%–10% MFB; and 5 the specific fuel consumption of B40 blend is within 10% of that of pure gasoline for stoichiometric mixture. Cet article évalue le potentiel de l’utilisation de différents mélanges butanolessence dans un moteur à allumage commandé à injection indirecte afin de quantifier l’influence de l’ajout de butanol sur les émissions des hydrocarbures imbrûlés (HC, le monoxyde de carbone (CO et les oxydes d’azote (NOx. De plus, l’influence sur la stabilité de combustion, le délai d’inflammation et sur la durée de la phase de combustion turbulente développée y sont également présentés. Les principaux résultats: 1 un mélange de 40% butanol et 60% essence (B40 par volume diminue les émissions de HC; 2 aucun effet significatif sur les émissions de NOx n’a été observé à l’exception du mélange 80% butanol/20% essence; 3 l’ajout de butanol améliore la stabilité de combustion ; 4 l’ajout de butanol réduit le délai d’inflammation, quantifié par la durée pour consommer 10% de masse de gaz frais; et 5 la consommation spécifique de carburant pour un mélange stoechiométrique de B40 est 10% sup

Model theory and algebraic geometry an introduction to E. Hrushovski’s proof of the geometric Mordell-Lang conjecture

CERN Document Server

1998-01-01

This introduction to the recent exciting developments in the applications of model theory to algebraic geometry, illustrated by E. Hrushovski's model-theoretic proof of the geometric Mordell-Lang Conjecture starts from very basic background and works up to the detailed exposition of Hrushovski's proof, explaining the necessary tools and results from stability theory on the way. The first chapter is an informal introduction to model theory itself, making the book accessible (with a little effort) to readers with no previous knowledge of model theory. The authors have collaborated closely to achieve a coherent and self- contained presentation, whereby the completeness of exposition of the chapters varies according to the existence of other good references, but comments and examples are always provided to give the reader some intuitive understanding of the subject.

Case Report: Atypical Cornelia de Lange Syndrome [version 2; referees: 1 approved, 2 approved with reservations

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Vito Leanza

2015-05-01

Full Text Available Cornelia de Lange Syndrome (CdLS (also called Bushy Syndrome or Amsterdam dwarfism, is a genetic disorder that can lead to several alterations. This disease affects both physical and neuropsychiatric development. The various abnormalities include facial dysmorphia (arched eyebrows, synophrys, depressed nasal bridge, long philtrum, down-turned angles of the mouth, upper-extremity malformations, hirsutism, cardiac defects, and gastrointestinal alterations. The prevalence of this syndrome is approximately one per 15,000. Ultrasound is not the perfect means to diagnose CdLS, however, many abnormalities can be detected prenatally by scrupulous image observation. We report an atypical CdLS case characterized by increased nuchal translucency in the first trimester, normal karyotype, saddle nose, micrognathia with receding jaw, low set ears, facies senilis, arthrogryposis of the hands, absence of the Aranzio ductus venous, dilatation of gallbladder and bowel, a unique umbilical artery, increased volume of amniotic fluid, and intrauterine growth retardation ending with the interruption of pregnancy.

"Virtual shear box" experiments of stress and slip cycling within a subduction interface mélange

Science.gov (United States)

Webber, Sam; Ellis, Susan; Fagereng, Åke

2018-04-01

What role does the progressive geometric evolution of subduction-related mélange shear zones play in the development of strain transients? We use a "virtual shear box" experiment, based on outcrop-scale observations from an ancient exhumed subduction interface - the Chrystalls Beach Complex (CBC), New Zealand - to constrain numerical models of slip processes within a meters-thick shear zone. The CBC is dominated by large, competent clasts surrounded by interconnected weak matrix. Under constant slip velocity boundary conditions, models of the CBC produce stress cycling behavior, accompanied by mixed brittle-viscous deformation. This occurs as a consequence of the reorganization of competent clasts, and the progressive development and breakdown of stress bridges as clasts mutually obstruct one another. Under constant shear stress boundary conditions, the models show periods of relative inactivity punctuated by aseismic episodic slip at rapid rates (meters per year). Such a process may contribute to the development of strain transients such as slow slip.

Alimentation des moteurs en mélange homogène pauvre Feeding Homogeneous Lean Mixtures to Engines

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Rayna B.

2006-11-01

Full Text Available Les études effectuées dans le cadre de plusieurs conventions de recherche entre l'Institut de Recherche des Transports (IRT et l'Institut Français du Pétrole (IFP associé à d'autres organismes industriels (Régie Nationale des Usines Renault (RNUR, Solex... ont permis a de caractériser l'influence de la préparation physique du mélange air-carburant sur le fonctionnement de moteurs monocylindre et multicylindre. L'effet sur le rendement d'inégalités de richesse entre les cylindres a été estimé à l'aide d'un modèle mathématique de simulation du moteur à allumage commandé ; b d'analyser les défauts inhérents à certains systèmes d'alimentation actuels et d'expérimenter des techniques différentes de formation du mélange carburé (car-burateur à dépression constante, pulvérisation pneumatique du carburant. Les résultats obtenus ont montré notamment que des améliorations ne peuvent résulter que d'un aménagement d'ensemble de tous les éléments du circuit d'admission Investigations carried out under thé terms of several research agreements involving Institut de Recherche des Transports (IRT and Institut Français du Pétrole (IFP associated with other industrial organizations (Régie Nationale des Usines Renault (RNUR, Solex served ta a Characterize thé influence of thé physical preparation of thé air/fuel mixture on thé operating of single-cylinder and multicylinder engines. The effect on thé efficiency of unequal air/fuel ratios among thé cylindres was evaluated by a mathematical model used ta simulate a spark-ignition engine. b Analyze thé inhérent defects of some fuel-supply systems now used and ta experiment with différent techniques of mixture preparation (constant depression car-burettor, pneumatic fuel spraying. The results obtained show, in particulor, that improvements con be produced only by redesigning all thé parts of thé fuel-supply circuit.

Forest Islands and Castaway Communities: REDD+ and Forest Restoration in Prey Lang Forest

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Courtney Work

2017-02-01

Full Text Available Climate Change policies are playing an ever-increasing role in global development strategies and their implementation gives rise to often-unforeseen social conflicts and environmental degradations. A landscape approach to analyzing forest-based Climate Change Mitigation policies (CCM and land grabs in the Prey Lang Forest landscape, Cambodia revealed two Korea-Cambodia partnership projects designed to increase forest cover that are juxtaposed in this paper. Case study data revealed a REDD+ project with little negative impact or social conflict in the project area and an Afforestation/Reforestation (A/R project that created both social and ecological conflicts. The study concludes that forest-based CCM policies can reduce conflict through efforts at minimal transformation of local livelihoods, maximal attention to the tenure rights, responsibilities, and authority of citizens, and by improving, not degrading, the project landscapes. The paper presents the circumstances under which these guidelines are sidestepped by the A/R project, and importantly reveals that dramatic forest and livelihood transformation had already affected the community and environment in the REDD+ project site. There are deep contradictions at the heart of climate change policies toward which attention must be given, lest we leave our future generations with nothing but forest islands and castaway communities.

L'auto adaptation à des mélanges essence/alcool utilisés comme carburant automobile: le moteur souple The Self-Adapting of Gasoline/Alcohol Mixtures Used As Automotive Fuel: the Flexible Engine

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Dorbon M.

2006-11-01

Full Text Available Le moteur souple est un moteur susceptible d'être alimenté par des carburants constitués de mélanges d'une essence classique et d'un alcool léger (méthanol ou éthanol; si la concentration de chacun des composants de ces mélanges varie, les réglages nécessaires au bon fonctionnement du véhicule se font automatiquement. Dans cet article, sont tout d'abord exposées les propriétés caractéristiques en tant que carburant automobile de l'un de ces alcools légers, le méthanol. Puis viennent les descriptions des dispositifs qui font le moteur souple c'est-à-dire d'une part les systèmes de reconnaissance du carburant et d'autre part les appareillages susceptibles de modifier les réglages du moteur (alimentation et allumage en fonction de la qualité du mélange consommé. A flexible engine is one capable of running on fuels consisting of mixtures of conventional gasoline and a light alcohol (methanol or ethanol. If the concentration of each of these components of such mixtures varies, the tuning required for the proper running of the vehicle takes place automatically. This article begins by describing the characteristic properties of one of these light alcohols (methanol as an automotive fuel. Then the equipment is described that makes an engine flexible, i. e. both the fuel recognition systems and the equipment capable of changing engine tuning (feed and ignition as a function of the quality of the mixture burned.

Destruksie ten minste tien maal beklemtoon – ’n interpretasie van 'Kraak die aardbol langs ’n naat' van Wilma Stockenström

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B. van der Westhuizen

2002-08-01

Full Text Available Destruction at least ten times emphasized – an interpretation of 'Kraak die aardbol langs ’n naat' ('Cracking the earth along the seam' by Wilma Stockenström In this article the value of syntactical analysis in the interpretation of a poem is investigated from the premise that emphasis can be effected inter alia in the following ways: (a by contravening certain rules that apply in standard language usage in order to compose grammatical sentences, b the exploitation of parallel syntactical structures, and c the relationship between sentence unit and line, and line and/or stanza. These theoretical points of departure form the basis of the syntactical analysis of “Kraak die aardbol langs ’n naat” (Wilma Stockenström, in which there are numerous deviations from the expected, normal and usual ways of constructing sentences. It is by these means that the semantic values gain prominence: the attention is drawn to the deviating behaviour of mankind continuing to destruct the earth until nothing remains. It is evident that the repeated use of irony and the satirical tone of this poem also contribute to persuade the reader to behave in a way opposite to that depicted in the poem. In this way the value of a syntactical analysis of this poem is illustrated. By uncovering the micro-structures (syntactical units within the (macro- structure (the poem, underlying patterns and the place of humanity in the universe can be better understood. In this way the analysis of this poem is then linked to the field of ecocriticism.

Séparation des mélanges eau-alcool à l'aide du CO2 supercritique : application au mélange éthanol eau Separation of Water-Alcohol Mixtures by Supercritical CO2: Application of the Ethanol- Water Mixture

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Fogel W.

2006-11-01

Full Text Available Les marchés accessibles à la technique d'extraction supercritique utilisant le CO2 seront plutôt orientés vers les alcools dérivés de la pétrochimie (isopropanol, butanol secondaire ou du gaz de synthèse (mélange d'alcools allant de l'éthanol à l'hexanol que vers les produits issus des fermentations pour lesquels la sélectivité de la séparation est théoriquement insuffisante et la concentration en alcool dans le moût fermenté trop faible. Markets for the supercritical extraction technique using CO2 will mainly be aimed for alcohols derived from petrochemicals (isopropanol, secondary butanol or from synthetic gas (mixture of alcohols ranging from ethanol to hexanol rather than for products from fermentations for which separation selectivity is theoretically insufficient and the alcohol concentration in the wort much too weak.

i-gel: a new supraglottic device for effective resuscitation of a very low birthweight infant with Cornelia de Lange syndrome

Science.gov (United States)

Galderisi, Alfonso; De Bernardo, Giuseppe; Lorenzon, Eleonora; Trevisanuto, Daniele

2015-01-01

Laryngeal Mask Airway (LMA) has been indicated as an effective device for airway management when face-mask ventilation and intubation have both failed in infants weighing >2000 g or delivered ≥34 weeks of gestation. All previous studies used a classic LMA. The current report describes the first case of a very low birthweight infant (1470 g, <3rd centile; 36+3gestational weeks) with micrognathia and palate cleft with Cornelia De Lange syndrome, resuscitated at birth with a new supraglottic airway device, i-gel size-1, positioned by a trainee paediatrician at first attempt. The procedure allowed reaching prompt effective ventilation and oxygenation of the patient, who was stabilised and intubated through i-gel. PMID:25809435

Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells

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Nicholas M. Provine

2018-04-01

Full Text Available Mucosal-associated invariant T (MAIT cells are innate-like T cells abundant in humans that can be activated in a TCR-independent manner by inflammatory and antiviral cytokines. In humans, the capacity for TCR-independent activation is functionally linked to a transcriptional program that can be identified by the expression of the C-type lectin receptor, CD161. In addition to MAIT cells, it has been demonstrated that a subset of γδT cells expresses CD161 and can be activated by TCR-independent cytokine stimulation. In this study, we sought to clarify the nature of cytokine-responsive human γδT cells. We could link CD161 expression on Vδ2+ versus Vδ1+ γδT cells to the observation that Vδ2+ γδT cells, but not Vδ1+ γδT cells, robustly produced IFN-γ upon stimulation with a variety of cytokine combinations. Interestingly, both CD161+ and CD161− Vδ2+ γδT cells responded to these stimuli, with increased functionality within the CD161+ subset. This innate-like responsiveness corresponded to high expression of PLZF and IL-18Rα, analogous to MAIT cells. Vδ2+ γδT cells in human duodenum and liver maintained a CD161+ IL-18Rα+ phenotype and produced IFN-γ in response to IL-12 and IL-18 stimulation. In contrast to MAIT cells, we could not detect IL-17A production but observed higher steady-state expression of Granzyme B by Vδ2+ γδT cells. Finally, we investigated the frequency and functionality of γδT cells in the context of chronic hepatitis C virus infection, as MAIT cells are reduced in frequency in this disease. By contrast, Vδ2+ γδT cells were maintained in frequency and displayed unimpaired IFN-γ production in response to cytokine stimulation. In sum, human Vδ2+ γδT cells are a functionally distinct population of cytokine-responsive innate-like T cells that is abundant in blood and tissues with similarities to human MAIT cells.

Executive functioning in Cornelia de Lange syndrome: domain asynchrony and age-related performance.

Science.gov (United States)

Reid, Donna; Moss, Jo; Nelson, Lisa; Groves, Laura; Oliver, Chris

2017-08-15

The aim of this study was to examine executive functioning in adolescents and adults with Cornelia de Lange syndrome (CdLS) to identify a syndrome and age-related profile of cognitive impairment. Participants were 24 individuals with CdLS aged 13-42 years (M = 22; SD = 8.98), and a comparable contrast group of 21 individuals with Down syndrome (DS) aged 15-33 years (M = 24; SD = 5.82). Measures were selected to test verbal and visual fluency, inhibition, perseverance/flexibility, and working memory and comprised both questionnaire and performance tests. Individuals with CdLS showed significantly greater impairment on tasks requiring flexibility and inhibition (rule switch) and on forwards span capacity. These impairments were also reported in the parent/carer-rated questionnaire measures. Backwards Digit Span was significantly negatively correlated with chronological age in CdLS, indicating increased deficits with age. This was not identified in individuals with DS. The relative deficits in executive functioning task performance are important in understanding the behavioural phenotype of CdLS. Prospective longitudinal follow-up is required to examine further the changes in executive functioning with age and if these map onto observed changes in behaviour in CdLS. Links with recent research indicating heightened responses to oxidative stress in CdLS may also be important.

Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells

OpenAIRE

Salerno-Goncalves, Ros?ngela; Luo, David; Fresnay, Stephanie; Magder, Laurence; Darton, Thomas C.; Jones, Claire; Waddington, Claire S.; Blohmke, Christoph J.; Angus, Brian; Levine, Myron M.; Pollard, Andrew J.; Sztein, Marcelo B.

2017-01-01

Gastrointestinal infections by Salmonella enterica serovar Typhi (S. Typhi) are rare in industrialized countries. However, they remain a major public health problem in the developing world with an estimated 26.9 million new cases annually and significant mortality when untreated. Recently, we provided the first direct evidence that CD8(+) MAIT cells are activated and have the potential to kill cells exposed to S. Typhi, and that these responses are dependent on bacterial load. However, MAIT c...

Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma.

Science.gov (United States)

Ishimori, Ayako; Harada, Norihiro; Chiba, Asako; Harada, Sonoko; Matsuno, Kei; Makino, Fumihiko; Ito, Jun; Ohta, Shoichiro; Ono, Junya; Atsuta, Ryo; Izuhara, Kenji; Takahashi, Kazuhisa; Miyake, Sachiko

2017-04-01

A variety of innate subsets of lymphoid cells such as natural killer (NK) cells, several populations of innate lymphoid cells (ILCs), and mucosal-associated invariant T (MAIT) cells as innate-like T lymphocytes are involved in asthma and may have important effector functions in asthmatic immune responses. In the present study, we investigated whether NK cells, ILCs, and MAIT cells in the peripheral blood of patients with asthma would be associated with clinical asthma parameters. We recruited 75 adult patients with mild to severe asthma. The peripheral blood mononuclear cells in peripheral venous blood samples from the patients were purified and stained with different combinations of appropriate antibodies. The cells were analyzed by flow cytometry. The percentage of activated (i.e., CD69 + ) NK cells in the total NK cell population was negatively correlated with FEV 1 % which is calculated by the forced expiratory volume in 1 s (FEV 1 )/the forced vital capacity (FVC). The percentages of CD69 + ILC1s and ILC2s were negatively correlated with FEV 1 % and %FEV 1 . The percentage of CD69 + ILC3s was positively correlated with BMI, and the percentage of CD69 + MAIT cells was negatively correlated with FEV 1 %. Moreover, the percentage of CD69 + NK cells, ILC1s, ILC2s, ILC3s, and MAIT cells were positively correlated with each other. For the first time, our data showed that activated NK cells, ILC1s, ILC2s, ILC3s, and MAIT cells were positively correlated with each other and may be associated with airflow limitation in patients with asthma. Copyright © 2016 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

Plaadid / Mait Eelrand

Index Scriptorium Estoniae

Eelrand, Mait, 1950-

2006-01-01

Uutest heliplaatidest JJ CAle & Eric Clapton "The Road To escondido", Fergie "The Dutchess", Cosmoskva "Juniper", "The Devil Wears Prada", Peaches "Impeach My Bush", Ludacris "Release Therapy", Milburn "Well Well Well"

Petrology and Geochemistry of Tethyan Mélange and Flysch Units Adjacent to the Yarlung Zangbo Suture Zone (YZSZ), Southern Tibet

Science.gov (United States)

Dupuis, C.; Hebert, R.; Wang, C.; Li, Y.; Li, Z.

2004-05-01

Located north of the Himalayas, the E-W trending YZSZ is mainly composed of remnants of the Neo-Tethys ocean-floor and marks the suture between Indian and Eurasian plates. This project aims to define geological units immediately South of the YZSZ ophiolites : the serpentinized ophiolitic mélange, the Jurassic-Cretaceous wildflysch and the Triassic flysch. The ophiolitic mélange is characterized by ultramafic rocks, which can be divided into 3 groups. Cpx-harzburgites contain brownish aluminous spinels with Mg# of 0.7-0.75 and Cr# of 0.15-0.27. They resemble fertile abyssal peridotites with generally smooth LREE-depleted and fairly flat MREE-HREE profiles. Transitional harzburgites contain reddish spinels with Mg# of 0.57-0.66 and Cr# of 0.35-0.46. They resemble depleted abyssal or supra-subduction zone peridotites in that MREE-HREE profiles have positive slopes indicative of high degrees of partial melting. LREE profiles vary from depleted to slightly enriched, consistent with some trapped or interacting melt or aqueous fluids. Harzburgites and dunites contain dark reddish spinels with Mg# of 0.47-0.68 and Cr# of 0.40-0.63. They have U-shaped profiles characteristics of interaction between LREE-enriched melt and REE-depleted mantle residues. Spinel compositions and fractional melting modelling indicate that Cpx-harburgites may be the residues from 5-15% melting, transitional harzburgites from 15-23% melting, and harzburgites and dunites from 22-29% melting. The South Sandwich arc-basin system is considered a modern analog of initial geodynamic setting. Mafic rocks (gabbros, diabases and basalts) are ubiquitous and can be geochemically subdivided according to their source unit. LREE-depleted profiles with average (La/Yb)N of 0.5 and slight negative Nb-Ta and Ti anomalies indicate that rocks from the ophiolitic mélange formed in a back-arc basin, such as back-arc-basin mafic rocks of the Izu-Bonin Arc. REE patterns of rocks from the wildflysch are LREE

Environmental monitoring program for the Ormen Lange Onshore Processing Plant and the Reserve Power Plant at Nyhamna, Gossa. Monitoring of vegetation and soil: re-analyses and establishment of new monitoring plots in 2010.; Miljoeovervaakingsprogram for Ormen Lange landanlegg og Reservegasskraftverk paa Nyhamna, Gossa. Overvaaking av vegetasjon og jord: gjenanalyser og nyetablering av overvaakingsfelter i 2010

Energy Technology Data Exchange (ETDEWEB)

Aarrestad, P.A.; Bakkestuen, V.; Stabbetorp, O.E.; Myklebost, Heidi

2011-07-01

The Ormen Lange Onshore Processing Plant in Aukra municipality (Moere og Romsdal county) receives unprocessed gas and condensate from the Ormen Lange field in the Norwegian Sea. During processing of sales gas and condensate, the plant emits CO, Co2, Nox, CH4, NMVOC (including BTEX), SO2 and small amounts of heavy metals, as specified in the discharge permit issued by the Climate and Pollution Directorate. The plant started production in 2007, with A/S Norske Shell as operator. In general, emissions of nitrogen and sulphur-containing gasses may affect terrestrial ecosystems through acidification and fertilization of soil and vegetation. The emissions from the onshore plant are calculated to be below the current critical loads for the terrestrial nature types. However, the nitrogen background level in the area of influence is close to the critical loads for oligotrophic habitats. To be able to document any effects of emissions to air on terrestrial ecosystems, a monitoring program for vegetation and soil was established in 2008 in the area of influence from the Ormen Lange Onshore Plant. The monitoring is planned at regular intervals according to the same methods employed in 2008, with the first reanalysis in 2010. The benefits of the monitoring parameters will be continuously evaluated. Statnett has established a Reserve Power Plant with discharge permits of similar substances in the same area as the Ormen Lange Onshore Processing plant, and participates in an extended monitor program from 2010. In 2008 two monitoring sites were established, one with rather high deposition of nitrogen north of the plant within Gule-Stavmyran nature reserve in Fraena municipality (site Gulmyran) and one south of the plant on the island Gossa (site Aukra). Deposition values have been estimated by the Norwegian Institute for Air Research (NILU). Within each site integrated monitoring of the species composition of the vegetation, plant growth, and chemical content of plants and soil is

Fluid inclusions in jadeitite and jadeite-rich rock from serpentinite mélanges in northern Hispaniola: Trapped ambient fluids in a cold subduction channel

Science.gov (United States)

Kawamoto, Tatsuhiko; Hertwig, Andreas; Schertl, Hans-Peter; Maresch, Walter V.

2018-05-01

Freezing-point depression was measured in aqueous fluid inclusions to determine salinities in six samples of jadeitite and jadeite-rich rock from the Jagua Clara serpentinite mélange of the Rio San Juan Complex, Dominican Republic. The mélange represents a fossil subduction-zone channel from a cold, mature subduction zone with a geothermal gradient of 6 °C/km. One hundred and twenty-five determinations of salinity in primary inclusions hosted in jadeite, quartz, apatite and lawsonite range between extremes of 1.2 and 8.7, but yield a well-defined mean of 4.5 ± 1.1 wt% (±1 s.d.) NaCl equiv, slightly higher than mean seawater (3.5 wt%). In one sample, eight additional fluid inclusions in quartz aligned along grain boundaries yield slightly lower values of 2.7 ± 1.3 wt% NaCl equiv. Homogenization temperatures were also measured for 47 fluid inclusions in two samples, but primary entrapment densities are not preserved. It is significant that the suite includes two types of samples: those precipitated directly from an aqueous fluid as well as examples of metasomatic replacement of a pre-existing magmatic rock. Nevertheless, the results indicate identical salinity for both types and suggest a much stronger genetic link between the two types of jadeitite and jadeite-rich rock than has previously been assumed. Based on the results of conductivity measurements in modern subduction zones, we envision a pervasive fluid in the subduction channel that evolved from salinity levels lower than those in sea-water up to the measured values due to on-going but largely completed serpentinization in the subduction channel. The present data represent a reference marker for the subduction channel of the Rio San Juan intra-oceanic subduction zone at 30-50 km depth and after 50-60 Myr of operation.

Interpretation of tracer tests performed in fractured rock of the Lange Bramke basin, Germany

Science.gov (United States)

Maloszewski, Piotr; Herrmann, Andreas; Zuber, Andrzej

Two multitracer tests performed in one of the major cross-fault zones of the Lange Bramke basin (Harz Mountains, Germany) confirm the dominant role of the fault zone in groundwater flow and solute transport. Tracers having different coefficients of molecular diffusion (deuterium, bromide, uranine, and eosine) yielded breakthrough curves that can only be explained by a model that couples the advective-dispersive transport in the fractures with the molecular diffusion exchange in the matrix. For the scale of the tests (maximum distance of 225m), an approximation was used in which the influence of adjacent fractures is neglected. That model yielded nearly the same rock and transport parameters for each tracer, which means that the single-fracture approximation is acceptable and that matrix diffusion plays an important role. The hydraulic conductivity of the fault zone obtained from the tracer tests is about 1.5×10-2m/s, whereas the regional hydraulic conductivity of the fractured rock mass is about 3×10-7m/s, as estimated from the tritium age and the matrix porosity of about 2%. These values show that the hydraulic conductivity along the fault is several orders of magnitude larger than that of the remaining fractured part of the aquifer, which confirms the dominant role of the fault zones as collectors of water and conductors of fast flow. Résumé Deux multitraçages ont été réalisés dans l'une des zones principales de failles du bassin de Lange Bramke (massif du Harz, Allemagne); les résultats confirment le rôle prédominant de la zone de failles pour l'écoulement souterrain et le transport de soluté. Les traceurs, possédant des coefficients de diffusion différents (deutérium, bromure, uranine et éosine), ont fourni des courbes de restitution qui ne peuvent être expliquées que par un modèle qui associe un transport advectif-dispersif dans les fractures à un échange par diffusion moléculaire dans la matrice. A l'échelle des expériences (distance

Who Wants to Save the Forest? Characterizing Community-Led Monitoring in Prey Lang, Cambodia

Science.gov (United States)

Turreira-García, Nerea; Meilby, Henrik; Brofeldt, Søren; Argyriou, Dimitris; Theilade, Ida

2018-06-01

Community monitoring is believed to be successful only where there is sustained funding, legislation for communities to enforce rules, clear tenure rights, and an enabling environment created by the state. Against this backdrop, we present the case of an autonomous grassroots-monitoring network that took the initiative to protect their forest, in a context, where no external incentives and rule enforcement power were provided. The aim was to analyze the socio-demographic and economic backgrounds, motivations and achievements of forest monitors, compared to non-monitors in the same communities. A total of 137 interviews were conducted in four villages bordering Prey Lang forest in Cambodia. We used binary logit models to identify the factors that influenced the likelihood of being a monitor. Results show that there were few (22%, n = 30) active monitors. Active monitors were intrinsically motivated forest-users, and not specifically associated with a particular gender, ethnicity, or residence-time in that area. The most common interventions were with illegal loggers, and the monitors had a general feeling of success in stopping the illegal activities. Most (73%, n = 22) of them had been threatened by higher authorities and loggers. Our results show that despite the lack of power to enforce rules, absence of external funding and land-ownership rights, and enduring threats of violence and conflicts, autonomous community monitoring may take place when community members are sufficiently motivated by the risk of losing their resources.

Jervell and Lange-Nielsen syndrome in a father and daughter from a large highly inbred family: a 16-year follow-up of 59 living members.

Science.gov (United States)

Sanyal, Shyamal Kumar; Kaul, Kanwar K; Hussein, Akhtar; Wilroy, Robert S; Agarwal, Kisan; Sohel, Saira

2013-08-01

To report the autosomal dominant inheritance of the Jervell and Lange-Nielsen syndrome in a highly inbred family, the initiation of Torsades de Pointes, and the natural history of the syndrome based on a 16-year follow-up of the kindred. A family tree was constructed that included 66 blood relatives from three successive generations. Electrocardiograms were obtained from 59 living members including the proband, four members from a nuclear family, and 54 from the extended family. Evoked response audiometry was recorded for the proband and the nuclear family. All 59 family members were followed up regularly for 16 years. A total of 24 living members were affected--QTc: 480-680 ms. The proband had long QTc, bilateral high-tone sensorineural deafness, recurrent syncope, and Torsades de Pointes. The asymptomatic father had long QTc and unilateral high-tone sensorineural deafness that involved specifically the left ear. One asymptomatic sibling of the proband had long QTc and normal hearing. The mother and another sibling were asymptomatic; QTc and hearing were normal in both. A total of 21 affected members from the extended family had only long QTc, and all were asymptomatic. There were three congenitally deaf first cousins who had recurrent syncope and adrenergic-triggered sudden death. In all, seven of 10 parents had consanguineous marriage to a first cousin. Each affected offspring had at least one affected parent. The severely symptomatic proband who received only β-blocker therapy and the 23 affected members without antiadrenergic therapy, all remained asymptomatic throughout the 16-year follow-up period. Jervell and Lange-Nielsen syndrome was inherited as autosomal dominant in this kindred. The majority of the affected members had a mild phenotype. The severity of auditory and cardiac phenotypes corresponded.

Cornelia de Lange Syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts.

Science.gov (United States)

Pistocchi, A; Fazio, G; Cereda, A; Ferrari, L; Bettini, L R; Messina, G; Cotelli, F; Biondi, A; Selicorni, A; Massa, V

2013-10-17

Cornelia de Lange Syndrome is a severe genetic disorder characterized by malformations affecting multiple systems, with a common feature of severe mental retardation. Genetic variants within four genes (NIPBL (Nipped-B-like), SMC1A, SMC3, and HDAC8) are believed to be responsible for the majority of cases; all these genes encode proteins that are part of the 'cohesin complex'. Cohesins exhibit two temporally separated major roles in cells: one controlling the cell cycle and the other involved in regulating the gene expression. The present study focuses on the role of the zebrafish nipblb paralog during neural development, examining its expression in the central nervous system, and analyzing the consequences of nipblb loss of function. Neural development was impaired by the knockdown of nipblb in zebrafish. nipblb-loss-of-function embryos presented with increased apoptosis in the developing neural tissues, downregulation of canonical Wnt pathway genes, and subsequent decreased Cyclin D1 (Ccnd1) levels. Importantly, the same pattern of canonical WNT pathway and CCND1 downregulation was observed in NIPBL-mutated patient-specific fibroblasts. Finally, chemical activation of the pathway in nipblb-loss-of-function embryos rescued the adverse phenotype and restored the physiological levels of cell death.

Suppressive and Enhancing Effects in Early Visual Cortex during Illusory Shape Perception: A Comment on Kok and de Lange (2014

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Pieter Moors

2015-02-01

Full Text Available In a recent functional magnetic resonance imaging study, Kok and de Lange (2014 observed that BOLD activity for a Kanizsa illusory shape stimulus, in which pacmen-like inducers elicit an illusory shape percept, was either enhanced or suppressed relative to a nonillusory control configuration depending on whether the spatial profile of BOLD activity in early visual cortex was related to the illusory shape or the inducers, respectively. The authors argued that these findings fit well with the predictive coding framework, because top-down predictions related to the illusory shape are not met with bottom-up sensory input and hence the feedforward error signal is enhanced. Conversely, for the inducing elements, there is a match between top-down predictions and input, leading to a decrease in error. Rather than invoking predictive coding as the explanatory framework, the suppressive effect related to the inducers might be caused by neural adaptation to perceptually stable input due to the trial sequence used in the experiment.

Vigotski contra James-Lange: crítica para uma teoria histórico-cultural das emoções

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Gisele Toassa

2012-03-01

Full Text Available Ponderações sobre as emoções humanas apresentaram-se em toda a obra do bielorrusso L. S. Vigotski, desde sua juvenil crítica de arte. Nesse tópico, debateu a contribuição de vários autores: Freud, Claparède, Ribot, Lewin, Wundt. Entretanto, a perspectiva mais analisada por ele foi a teoria James-Lange. O objetivo deste artigo é discutir a extensa crítica que Vigotski dirigiu a ela no manuscrito “Utchenie ob Emotsiakh”, a qual se enquadrava numa ampla atitude teórico-metodológica do autor: a de compilar e relacionar o material fatual sem coordenação, expondo a luta de ideias filosóficas por detrás das psicológicas, de modo a abrir caminho para futuras investigações destinadas à superação do dualismo na psicologia. A partir dos principais fundamentos vigotskianos para futuros estudos, discutimos essa querela acerca das emoções, tema que o bielorrusso considerava a parte mais difícil e, possivelmente, a mais importante para o futuro da ciência psicológica.

Päev, mil sa midagi ei ostnud / Aet Annist

Index Scriptorium Estoniae

Annist, Aet

1999-01-01

Kuus aastat on Kalle Lasni juhitud organisatsiooni Media Foundations, teinud tarbimisvastast reklaami ja kutsunud tähistama 26. nov.-t ostuvaba päevana. Algselt ameerika ostjaskonnale suunatud üleskutse on jõudnud ülejäänud tarbimisühiskondadeni. Ajakirjast 'Ethical Consumerism', mis kogub kirjeldusi Täiesti Mittevajalikest Asjust (TYNKYNS) ning lisab sapiseid soovitusi nende omandajatele

Kuidas parandada elu Eestis - 1943. a. variant / Sirje Annist

Index Scriptorium Estoniae

Annist, Sirje

2006-01-01

Artikkel on jätkuks ajakirjas Kultuur ja Elu (1994, nr. 1-2) ilmunud lühitutvustusele "Kahtlaste leitud paberite lugu proloogi ja epiloogiga. Saksa okupatsiooni aegne autonoomiakava". Lisa: Raport poliitilisest kriisist ning selle tagajärgedest Eestis. Lk. 78-88

Mucosal-associated invariant T cell is a potential marker to distinguish fibromyalgia syndrome from arthritis.

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Chie Sugimoto

Full Text Available Fibromyalgia (FM is defined as a widely distributed pain. While many rheumatologists and pain physicians have considered it to be a pain disorder, psychiatry, psychology, and general medicine have deemed it to be a syndrome (FMS or psychosomatic disorder. The lack of concrete structural and/or pathological evidence has made patients suffer prejudice that FMS is a medically unexplained symptom, implying inauthenticity. Furthermore, FMS often exhibits comorbidity with rheumatoid arthritis (RA or spondyloarthritis (SpA, both of which show similar indications. In this study, disease specific biomarkers were sought in blood samples from patients to facilitate objective diagnoses of FMS, and distinguish it from RA and SpA.Peripheral blood mononuclear cells (PBMCs from patients and healthy donors (HD were subjected to multicolor flow cytometric analysis. The percentage of mucosal-associated invariant T (MAIT cells in PBMCs and the mean fluorescent intensity (MFI of cell surface antigen expression in MAIT cells were analyzed.There was a decrease in the MAIT cell population in FMS, RA, and SpA compared with HD. Among the cell surface antigens in MAIT cells, three chemokine receptors, CCR4, CCR7, and CXCR1, a natural killer (NK receptor, NKp80, a signaling lymphocyte associated molecule (SLAM family, CD150, a degrunulation marker, CD107a, and a coreceptor, CD8β emerged as potential biomarkers for FMS to distinguish from HD. Additionally, a memory marker, CD44 and an inflammatory chemokine receptor, CXCR1 appeared possible markers for RA, while a homeostatic chemokine receptor, CXCR4 deserved for SpA to differentiate from FMS. Furthermore, the drug treatment interruption resulted in alternation of the expression of CCR4, CCR5, CXCR4, CD27, CD28, inducible costimulatory molecule (ICOS, CD127 (IL-7 receptor α, CD94, NKp80, an activation marker, CD69, an integrin family member, CD49d, and a dipeptidase, CD26, in FMS.Combined with the currently available

Mucosal-associated invariant T cell is a potential marker to distinguish fibromyalgia syndrome from arthritis.

Science.gov (United States)

Sugimoto, Chie; Konno, Takahiko; Wakao, Rika; Fujita, Hiroko; Fujita, Hiroyoshi; Wakao, Hiroshi

2015-01-01

Fibromyalgia (FM) is defined as a widely distributed pain. While many rheumatologists and pain physicians have considered it to be a pain disorder, psychiatry, psychology, and general medicine have deemed it to be a syndrome (FMS) or psychosomatic disorder. The lack of concrete structural and/or pathological evidence has made patients suffer prejudice that FMS is a medically unexplained symptom, implying inauthenticity. Furthermore, FMS often exhibits comorbidity with rheumatoid arthritis (RA) or spondyloarthritis (SpA), both of which show similar indications. In this study, disease specific biomarkers were sought in blood samples from patients to facilitate objective diagnoses of FMS, and distinguish it from RA and SpA. Peripheral blood mononuclear cells (PBMCs) from patients and healthy donors (HD) were subjected to multicolor flow cytometric analysis. The percentage of mucosal-associated invariant T (MAIT) cells in PBMCs and the mean fluorescent intensity (MFI) of cell surface antigen expression in MAIT cells were analyzed. There was a decrease in the MAIT cell population in FMS, RA, and SpA compared with HD. Among the cell surface antigens in MAIT cells, three chemokine receptors, CCR4, CCR7, and CXCR1, a natural killer (NK) receptor, NKp80, a signaling lymphocyte associated molecule (SLAM) family, CD150, a degrunulation marker, CD107a, and a coreceptor, CD8β emerged as potential biomarkers for FMS to distinguish from HD. Additionally, a memory marker, CD44 and an inflammatory chemokine receptor, CXCR1 appeared possible markers for RA, while a homeostatic chemokine receptor, CXCR4 deserved for SpA to differentiate from FMS. Furthermore, the drug treatment interruption resulted in alternation of the expression of CCR4, CCR5, CXCR4, CD27, CD28, inducible costimulatory molecule (ICOS), CD127 (IL-7 receptor α), CD94, NKp80, an activation marker, CD69, an integrin family member, CD49d, and a dipeptidase, CD26, in FMS. Combined with the currently available

On-line valve monitoring at the Ormen Lange gas plant

Energy Technology Data Exchange (ETDEWEB)

Greenlees, R.; Hale, S. [Score Atlanta Inc., Kennesaw, Georgia (United States)

2011-07-01

The purpose of this presentation is to discuss replacing time and labor intensive nuclear outage activities with on line condition monitoring solutions, primarily the periodic verification of MOV functionality discussed in USNRC Generic Letter 96.05. This regulation requires that MOV age related performance degradations are properly identified and accounted for, causing utilities to have to retest valves periodically for the duration of the plants operating license. AECL designed CANDU reactors have a world class performance and safety record, with typical average annual capacity factors of 90%. The CANDU reactor design has the ability to refuel on line, as a result (a) it can be a challenge scheduling all required valve testing into limited duration outage work windows, (b) at multi unit sites, Unit 0 valves can be difficult to test because they are rarely ever out of service, (c) deuterium-oxide (heavy water) moderator is expensive to manufacture, as a result, effective through valve leakage monitoring is essential. These three factors alone make CANDU sites the most suitable candidates for on line valve monitoring systems. Nuclear industry regulations have been instrumental in the development of 'at the valve' diagnostic systems, but diagnostic testing has not typically been utilized to the same degree in other less regulated industries. However, that trend is changing, and the move toward valve diagnostics and condition monitoring has moved fastest in the offshore oil and gas industry on the Norwegian side of the North Sea. The Ormen Lange plant, located on Nyhamna Island on the west coast of Norway, operated by Shell, is one of the worlds most advanced gas processing plants. A stated maintenance goal for the plant is that 70% of the maintenance budget and spend should be based on the results of on line condition monitoring, utilizing monitoring systems equipped with switch sensing, strain gages, hydraulic and pneumatic pressure transducers and

On-line valve monitoring at the Ormen Lange gas plant

International Nuclear Information System (INIS)

Greenlees, R.; Hale, S.

2011-01-01

The purpose of this presentation is to discuss replacing time and labor intensive nuclear outage activities with on line condition monitoring solutions, primarily the periodic verification of MOV functionality discussed in USNRC Generic Letter 96.05. This regulation requires that MOV age related performance degradations are properly identified and accounted for, causing utilities to have to retest valves periodically for the duration of the plants operating license. AECL designed CANDU reactors have a world class performance and safety record, with typical average annual capacity factors of 90%. The CANDU reactor design has the ability to refuel on line, as a result (a) it can be a challenge scheduling all required valve testing into limited duration outage work windows, (b) at multi unit sites, Unit 0 valves can be difficult to test because they are rarely ever out of service, (c) deuterium-oxide (heavy water) moderator is expensive to manufacture, as a result, effective through valve leakage monitoring is essential. These three factors alone make CANDU sites the most suitable candidates for on line valve monitoring systems. Nuclear industry regulations have been instrumental in the development of 'at the valve' diagnostic systems, but diagnostic testing has not typically been utilized to the same degree in other less regulated industries. However, that trend is changing, and the move toward valve diagnostics and condition monitoring has moved fastest in the offshore oil and gas industry on the Norwegian side of the North Sea. The Ormen Lange plant, located on Nyhamna Island on the west coast of Norway, operated by Shell, is one of the worlds most advanced gas processing plants. A stated maintenance goal for the plant is that 70% of the maintenance budget and spend should be based on the results of on line condition monitoring, utilizing monitoring systems equipped with switch sensing, strain gages, hydraulic and pneumatic pressure transducers and acoustic leakage

Analysis of Simultaneous Gas-Liquid Flow Through an Orifice and Its Application to Flow Metering Etude de l'écoulement simultané d'un mélange gaz-liquide à travers un orifice et son application à la mesure du débit

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Pascal H.

2006-11-01

Full Text Available The purpose of this article is to show a more accurate orifice equation for a two-phase flow, such a compressible mixture of gas and liquid. The orifice equation given here con be used for the measurement of a gas-liquid mixture of fine emulsions by the orificemeter method. From the thermodynamic point of view, an equation of state has been formulated which provides the relationship between the specific mass of the mixture and pressure, under conditions of adiabatic expansion. The results obtained enable the mass flow rates of gas and liquid ta be determined without separation of the phases, provided thot the gas liquid mass ratio is known. The critical pressure ratio corresponding ta sonic velocity is also determined. Cet article présente une relation plus précise pour l'écoulement d'un système à deux phases, tel qu'un mélange compressible gaz-liquide, à travers un diaphragme. Cette relation peut être utilisée pour des mesures de mélanges gaz-liquide très finement divisés, c'est-à-dire des émulsions ou brouillards, par la méthode du diaphragme en paroi mince. Du point de vue thermodynamique, on a formulé une équation d'état donnant la relation entre la masse spécifique du mélange et la pression dans des conditions d'expansion adiabatique. Les résultats obtenus per-mettent de déterminer le débit massique du gaz et du liquide, sans séparation des deux phases, à condition que le rapport de masse gaz-liquide soit connu. On détermine également le rapport de pression critique correspondantà la vitesse du son.

Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

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Miguel Tolosa Igualada

2016-05-01

Full Text Available http://dx.doi.org/10.5007/2175-7968.2016v36n2p291 Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

Premixed Turbulent Flames and Spectral Approach Flammes turbulentes de prémélange Approche spectrale

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Mathieu J.

2006-11-01

the behaviour of flames developing in a turbulent field can be easily understood. This approach could also open the way to new modeling methods. Indépendamment de l'intérêt scientifique que présentent les flammes de prémélange, les applications industrielles sont nombreuses. Dans cet article la flamme est supposée se développer dans un milieu turbulent ce qui oblige à une comparaison précise des échelles associées à la flamme et de celles associées à la turbulence. Cette confrontation n'est pas nouvelle. Cet article montre que ces comparaisons peuvent s'enrichir si l'on accepte une description spectrale de la turbulence faisant largement référence à de nombreux travaux antérieurs. La notion de champ extérieur turbulent agissant sur la flamme et celle de champ turbulent envahissant la flamme apparaît clairement lors d'une représentation spectrale. On voit également comment l'on passe continûment d'une situation avec front de réaction à une autre où la réaction s'effectue en volume tandis que se développe une compétition entre une réaction chimique qui tend à générer une ségrégation des espèces et une diffusion turbulente qui provoque le mélange. Dans les moteurs à combustion avec prémélange il existe un grand nombre de situations possibles dépendant de la vitesse de rotation. On conçoit aisément qu'une modélisation unique valable quel que soit le régime ne soit guère envisageable. Il y a là aussi matière à réflexions. Autre sujet au demeurant ouvert est celui de la modélisation. Dans le présent article certaines structures turbulentes sont étudiées. Resterait à savoir si une architecture spécifique de moteur n'est pas capable de générer des structures turbulentes particulières. Jusqu'ici le rôle de tourbillons privilégiés avait été introduit par la voie de séquences de tourbillons. L'approche spectrale permet de considérer un ensemble continu de structures analogues intervenant dans un phénomène de

Paweł Bąk, Die Metapher in der Übersetzung. Studien zum Transfer der Aphorismen von Stanisław Jerzy Lec und der Gedichte von Wisława Szymborska, Peter Lang Europäischer Verlag der Wissenschaft en, Frankfurt am Main u. a. 2007 =...

OpenAIRE

Zieliński, Lech

2008-01-01

Paweł Bąk, Die Metapher in der Ubersetzung. Studien zum Transfer der Aphorismen von Stanisław Jerzy Lec und der Gedichte von Wisława Szymborska, Peter Lang Europaischer Verlag der Wissenschaft en, Frankfurt am Main u. a. 2007 = Danziger Beitrage zur Germanistik, Bd. 20 wyd. Andrzej Kątny, 332 strony

Patients Carrying 9q31.1-q32 Deletion Share Common Features with Cornelia de Lange Syndrome

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Ruixue Cao

2015-01-01

Full Text Available Background: Cornelia de Lange Syndrome (CdLS is a rare but severe clinically heterogeneous developmental disorder characterized by facial dysmorphia, growth and cognitive retardation, and abnormalities of limb development. Objectives: To determine the pathogenesis of a patient with CdLS. Methods: We studied a patient with CdLS by whole exome sequencing, karyotyping and Agilent CGH Array. The results were confirmed by quantitative real-time PCR analysis of the patient and her parents. Further comparison of our patient and cases with partially overlapping deletions retrieved from the literature and databases was undertaken. Results: Whole exome sequencing had excluded the mutation of cohesion genes such as NIPBL,SMC1A and SMC3. The result of karyotyping showed a deletion of chromosome 9q31.1-q32 and the result of Agilent CGH Array further displayed a 12.01-Mb region of deletion at chromosome bands 9q31.1-q32. Reported cases with the deletion of 9q31.1-q32 share similar features with our CdLS patient. One of the genes in the deleted region, SMC2, belongs to the Structural Maintenance of Chromosomes (SMC family and regulates gene expression and DNA repair. Conclusions: Patients carrying the deletion of 9q31.1-q32 showed similar phenotypes with CdLS.

从对电视剧《施琅大将军》的争论看 中国文化民族主义复兴的困境 (The Dilemma of Chinese Cultural Nationalism: the Case of the TV Program 'General Shi Lang'

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Mobo Gao

2007-01-01

Full Text Available With the rise of China's status on international stage as a result of its economic development there is an increasingly audible voice of Chinese cultural nationalism. More and more educators and intellectuals are calling for the revival of Chinese traditional culture values. However, the very issues of who are the Chinese and what are traditional Chinese cultural values present a huge dilemma. The debates on a recent a TV program "General Shi Lang" consist a good case to illustrate this dilemma. Shi Lang was a general of the last days of the Ming Dynasty, but had surrendered to the Manchu Qing dynasty invaders and fought for the Machus take over Taiwan from a Chinese ruler. The debates show that the dilemma has its cause in at least three issues. First, it is not at all obvious who should be categorized as Chinese. Secondly, it is not at all obvious what Chinese cultural values are. And finally it is the issue of evaluation of traditional values against the universal claim of the values of liberal democracy.

Potentiel des moteurs à mélange pauvre face aux moteurs actuels à réglage stoechiométrique : consommation, émissions, exigence en octane The Challenge to Modern Stoichiometric Engines by the Potential Lean-Burn Engine: Consumption, Emissions, Fuel Requirements

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Douaud A. M.

2006-11-01

Full Text Available Le moteur à allumage commandé pour application automobile aux États-Unis est généralement dépollué par catalyse trifonctionnelle qui impose un contrôle stoechiométrique du mélange air-carburant. Le contexte européen de 1990 pour la qualité de l'air stimule l'industrie automobile dans ses recherches de solutions techniques performantes. Le moteur à mélange pauvre, performant en consommation, est une solution potentielle si l'émission de NOx peut être maîtrisée par la combustion. Cet objectif nécessite une conception du moteur contrôlant la turbulence et l'hétérogénéité du mélange air + carburant + résiduels pendant la combustion. La longévité de l'adaptation optimale moteur-carburant nécessitera un contrôle électronique de l'allumage et l'utilisation d'additifs détergents. Pour satisfaire les réglementations les plus sévères, les émissions de CO et HC pourront être contrôlées par un simple pot catalytique d'oxydation. Des oxydes de métaux non précieux introduits dans la formule catalytique en addition aux métaux précieux maintiennent la fonction oxydante pendant les transitoires en mélange riche tout en réduisant partiellement les NOx. Une vue d'ensemble de ce concept basé sur des simulations numériques et des résultats expérimentaux de consommation, d'émission, d'exigence en octane, etc. est présentée. Spark-ignition engines for automotive applications in the United States are currently depolluted by a 3-way catalyst that requires air-fuel control at stoichiometry. The 1990 European context for air pollution control is stimulating the automotive industry to search for improved technical solutions. The lean-burn engine is a potential fuel-efficient answer if its combustion can be optimized for low NOx emissions. Achieving this challenging approach requires engine design to control the turbulence and heterogeneity of the air + fuel + residual mixture during combustion. Electronic ignition

Bill Lang's contributions to acoustics at International Business Machines Corporation (IBM), signal processing, international standards, and professionalism in noise control engineering

Science.gov (United States)

Maling, George C.

2005-09-01

Bill Lang joined IBM in the late 1950s with a mandate from Thomas Watson Jr. himself to establish an acoustics program at IBM. Bill created the facilities in Poughkeepsie, developed the local program, and was the leader in having other IBM locations with development and manufacturing responsibilities construct facilities and hire staff under the Interdivisional Liaison Program. He also directed IBMs acoustics technology program. In the mid-1960s, he led an IEEE standards group in Audio and Electroacoustics, and, with the help of James Cooley, Peter Welch, and others, introduced the fast Fourier transform to the acoustics community. He was the convenor of ISO TC 43 SC1 WG6 that began writing the 3740 series of standards in the 1970s. It was his suggestion to promote professionalism in noise control engineering, and, through meetings with Leo Beranek and others, led the founding of INCE/USA in 1971. He was also a leader of the team that founded International INCE in 1974, and he served as president from 1988 until 1999.

Lang, S. K. W. and Gardiner, B. D. (2014). "As They Like It--Culture-Centred Counsellor Education in the Context of Aotearoa New Zealand: A Play on Bicultural Pluralism." "British Journal of Guidance and Counselling", 42 (1), 73-85. doi.org./10.1080/03069885.2013.824949

Science.gov (United States)

Au Yeung, Helen

2016-01-01

In their article, Lang and Gardiner draw support from the Treaty of Waitangi to deconstruct cultural dominance and reconstruct a framework, which promotes bicultural pluralism in the new counsellor education programme at the Massey University. However, they omit significant details of the Treaty and therefore mislead the audience to think that the…

Maternal Adaptive Immune Cells in Decidua Parietalis Display a More Activated and Coinhibitory Phenotype Compared to Decidua Basalis

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Martin Solders

2017-01-01

Full Text Available The maternal part of the placenta, the decidua, consists of maternal immune cells, decidual stromal cells, and extravillous fetal trophoblasts. In a successful pregnancy, these cell compartments interact to provide an intricate balance between fetal tolerance and antimicrobial defense. These processes are still poorly characterized in the two anatomically different decidual tissues, basalis and parietalis. We examined immune cells from decidua basalis and parietalis from term placentas (n=15 with flow cytometry. By using multivariate discriminant analysis, we found a clear separation between the two decidual compartments based on the 81 investigated parameters. Decidua parietalis lymphocytes displayed a more activated phenotype with a higher expression of coinhibitory markers than those isolated from basalis and contained higher frequencies of T regulatory cells. Decidua basalis contained higher proportions of monocytes, B cells, and mucosal-associated invariant T (MAIT cells. The basalis B cells were more immature, and parietalis MAIT cells showed a more activated phenotype. Conventional T cells, NK cells, and MAIT cells from both compartments potently responded with the production of interferon-γ and/or cytotoxic molecules in response to stimulation. To conclude, leukocytes in decidua basalis and parietalis displayed remarkable phenotypic disparities, indicating that the corresponding stromal microenvironments provide different immunoregulatory signals.

Daniel Gallego Hernández (Ed.). Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

OpenAIRE

Miguel Tolosa Igualada

2016-01-01

Daniel Gallego-Hernández (ed.). Current Approaches to Business and Institutional Translation. Proceedings of the International Conference on Economic, Business, Financial and Institutional Translation / Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suíça: Peter Lang, 2015, 254 páginas. ISBN 978-3-0343-1656-9.

Mentorklubi süstib väikeettevõtjale tegutsemiskindlust / Teeli Remmelg

Index Scriptorium Estoniae

Remmelg, Teeli

2005-01-01

Tallinna Mentorklubi tegevusest, kus väikeettevõtjad õpivad üksteise vigadest ja õnnestumistest. Kommenteerivad EASi mentorprogrammi koordinaator Liina Võrkaed ja Pro Konsultatsioonid, Tallinna Mentorklubi mentor Mait Raava

The importance of deciduous forest for alkalinity, phosphorus burial and isoetid macrophytes as revealed by a recent paleo study in a soft water Lobelia Lake (Grane Langsø, Denmark)

DEFF Research Database (Denmark)

Klamt, Anna-Marie; Reitzel, Kasper; Mortensen, Morten F.

Lake Grane Langsø is characterized by nutrient-poor soft water with very high visibilities and hence contains rare isoetid species (such as Isoetes lacustris, Littorella uniflora and Lobelia dortmanna). Pollen data and old maps show that the dominating vegetation in the catchment area of Lake Grane...... clearly reduced the amounts of macrofossils for Isoetes sp., Lobelia sp. and Characeans. This suggests a reduction in their maximum distribution depth because of enhanced influx of terrestrial material and subsequently reduced water transparencies. Overall this paleo-study underlines the sensitivity...... of nutrient-poor soft water lakes to changes in their catchments vegetation and their partial irreversible consequences and is therefore of importance for lake management....

Kaebus sunnib teatreid suitsetamise osas aru pidama

Index Scriptorium Estoniae

2009-01-01

Draamateatri külastaja kaebuse peale - etenduses "Pedro Páramo" suitsetas näitleja Mait Malmsten kogu esimese vaatuse - arutab Eesti Etendusasutuste Liit peagi laval suitsetamisega seotud küsimusi

Role of non-conventional T lymphocytes in respiratory infections: the case of the pneumococcus.

Directory of Open Access Journals (Sweden)

Stoyan Ivanov

2014-10-01

Full Text Available Non-conventional T lymphocytes constitute a special arm of the immune system and act as sentinels against pathogens at mucosal surfaces. These non-conventional T cells (including mucosal-associated invariant T [MAIT] cells, gamma delta [γδ] T cells, and natural killer T [NKT] cells display several innate cell-like features and are rapidly activated by the recognition of conserved, stress-induced, self, and microbial ligands. Here, we review the role of non-conventional T cells during respiratory infections, with a particular focus on the encapsulated extracellular pathogen Streptococcus pneumoniae, the leading cause of bacterial pneumonia worldwide. We consider whether MAIT cells, γδ T cells, and NKT cells might offer opportunities for preventing and/or treating human pneumococcus infections.

Keha võõras nahas ehk antropoloogiline eksperimentalism / Aet Annist

Index Scriptorium Estoniae

Annist, Aet

2009-01-01

Eksperimentidest kunstis ja antropoloogias. Kristina Normani kunstiprojektist kuldse pronkssõduriga ja Ameerika valge ajakirjaniku John H. Griffini eksperimendist veeta kuus nädalat mustanahalisena USA lõunaosariikides

Vene Kultuurikeskus = The Russian Culture Centre / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Mere puiestee 5 asuva hoone (arhitekt A. Kuznetsov, 1954) restaureerimisest. Arhitekt Niina Mäger, sisearhitekt Anne Tamverk. Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

Inimesed ja mesilased / Rein Tootmaa

Index Scriptorium Estoniae

Tootmaa, Rein

2005-01-01

Nukufilm "Gene+ratio" : stsenarist, kunstnik ja režissöör Mait Laas : konsultant Paavo Matsin : operaatorid Ragnar Neljandi, Raivo Möllits : helilooja Tiit Kikas : Nukufilm OÜ - Icon Film (Saksamaa) 2005

Tri gorsti za Tsentralnõi rõnok / Arvi Tapver

Index Scriptorium Estoniae

Tapver, Arvi

1999-01-01

Mõrvatud endise abilinnapea Mait Metsamaa keskturu erastajatest kaaskond kahlustas tunnistaja sõnul topeltmängu, kui Metsamaa vanale sõbrale ja allilmas kardetavale Meelis Laole erastamisest loobumise eest hüvitist pakkus

O Novo Partido Anticapitalista francês: nova batalha numa antiga guerra?

Directory of Open Access Journals (Sweden)

Leandro de Oliveira Galastri

2009-11-01

Full Text Available

lang="EN-US">Estelang="EN-US"> lang="EN-US">artigolang="EN-US"> pretende lang="EN-US">apresentarlang="EN-US">, de lang="EN-US">formalang="EN-US"> lang="EN-US">brevelang="EN-US">, algumas lang="EN-US">questõeslang="EN-US"> relativas à lang="EN-US">formaçãolang="EN-US"> do lang="EN-US">Novolang="EN-US"> lang="EN-US">Partidolang="EN-US"> lang="EN-US">Anticapitalistalang="EN-US"> lang="EN-US">francêslang="EN-US">, o NPA. Criado no início de 2009 a partir da dissolução da tradicional organização trotskista Liga Comunista Revolucionária (LCR, o NPA surge como uma agremiação descentralizada, cujo objetivo é aglutinar em seu seio diversas correntes e movimentos políticos de esquerda, no intuito de construir uma resistência mais efetiva às forças do capital.

Vana kaader järel-eesti ajal võimalusi proovimas / Maie Kalda

Index Scriptorium Estoniae

Kalda, Maie, 1929-2013

2001-01-01

Artikkel põhineb konverentsil "Kohandumise märgid" (20. apr. 2001) peetud ettekandel. Kirjanike elu- ja loominguloost a-tel 1944-1948, lähemalt Mait Metsanurgast, Hugo Raudsepast, Friedebert Tuglasest ja Oskar Lutsust

Tallinna Loomeinkubaator = Creative Incubator in Tallinn / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Veerenni 24C asuva Tallinna Loomeinkubaatori sisekujundusest. Sisearhitektid Raul Tiitus, Tarmo Piirmets (Pink OÜ), graafiline kujundus: Kaarel Vahtramäe (Velvet Studio). Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud sisekujundusele

Juutide uurimine tõi tunnustuse : eesti teadlaste artikkel jõudis maailma tippajakirja / Marju Himma

Index Scriptorium Estoniae

Himma, Marju

2010-01-01

Juutide erinevate kogukondade genotüübilistele erinevuste uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayev, Mait Metspalu ja Richard Villems. Artikkel ilmus teadusajakirjas Nature

Esilinastus väge täis "Mina olin siin" / Kutt Kommel

Index Scriptorium Estoniae

Kommel, Kutt

2008-01-01

Rene Vilbre noortefilm "Mina olin siin", mille aluseks on Sass Henno romaan "Mina olin siin. Esimene arest" : operaator Mait Mäekivi : osades Rasmus Kaljujärv, Hele Kõre jt : Amrion Productions - Helsinki-filmi OY 2008

Veider nelik jätkab!

Index Scriptorium Estoniae

2008-01-01

Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (lavastanud Tim McGrath ja Eric Darnell, eesti keeles loevad teksti Karol Kuntsel, Andero Ermel, Evelin Pang, Argo Aadli, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik, Anne Reemann jt)

Endine turujuht end süüdi ei tunnistanud / Hannes Krause

Index Scriptorium Estoniae

Krause, Hannes

2005-01-01

Vadim Polishtshuk, keda süüdistatakse koos kahe kaaslasega Mait Metsamaa mõrvaprotsessi peamise tunnistaja ähvardamise ja mõjutamise katses, ei tunnistanud end 19. septembril Tallinna linnakohtus alanud protsessil süüdi

Akna varastamine : eesti Y-kirjandus / Berk Vaher

Index Scriptorium Estoniae

Vaher, Berk, 1975-

2014-01-01

Valdur Mikita, Erkki Luuk'i, Kiwa, Kaspari ja kirjanike rühmituse “14 NÜ” (Mait Laas, Paavo Matsin, Marko Mägi, Erkki Kadarik, Marianne Ravi, Maarja Vaino, Trip Jarvis, Johannes Üksi) loomingust

Eesti animafilmid võitsid Raumas

Index Scriptorium Estoniae

pPIK mare 2010

1999-01-01

VI Sinise Mere filmifestivalil Raumas jagasid A-sarjas esikohta Mait Laasi "Päevavalgus" ja Peep Pedmansoni "Just Märried", teiseks jäi Märt Sildvee "Guardian Angel" ja kolmandaks Riho Undi - Hardi Volmeri "Primavera"

Nukufilm lasi käiku pooletunnise 3D-seiklusfilmi / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2009-01-01

Stuudios Nukufilm algasid pooletunnise 3D-nukufilmi "Lisa Limone ja Maroc Orange'i tormakas armulugu" võtted. Filmi režissöör on Mait Laas, stsenaristid Kati Kovacs ja Peep Pedmanson, produtsent Arvo Nuut

A rhinocerotid-dominated megafauna at the MIS6-5 transition: The late Middle Pleistocene Coc Muoi assemblage, Lang Son province, Vietnam

Science.gov (United States)

Bacon, Anne-Marie; Antoine, Pierre-Olivier; Huong, Nguyen Thi Mai; Westaway, Kira; Tuan, Nguyen Anh; Duringer, Philippe; Zhao, Jian-xin; Ponche, Jean-Luc; Dung, Sam Canh; Nghia, Truong Huu; Minh, Tran Thi; Son, Pham Thanh; Boyon, Marc; Thuy, Nguyen Thi Kim; Blin, Amandine; Demeter, Fabrice

2018-04-01

Little is known about the ecosystems in the north of the Indochinese peninsula at the Middle-Late Pleistocene transition. In this paper, we analyzed the new fauna from Coc Muoi cave, Lang Son province, northeast Vietnam. In comparison with other well-documented faunas from the region, that of Coc Muoi is distinguished by the predominance of rhinoceroses among diverse large-bodied herbivores. The results of the OSL and pIR-IRSL dating of the cave sediments and U-series dating of flowstones indicate a potential age range of 148-117 ka for the fauna (MIS6-5). The analysis of age-at-death distributions of rhinoceroses, wild cattle, sambar deer, and wild pig, does not show any apparent selectivity of age classes. We also focused our study on rhinoceroses, tapirs, and wild cattle by analyzing the prevalence of hypoplastic defects on deciduous and permanent teeth, in an attempt to assess the health status of the taxa during their first years of growth. The health status of large-bodied herbivores (kouprey and rhinoceros) reveals the importance of stressors (biotic and abiotic) in the rainforest environment during a period of marked climatic transition (MIS6-5) in comparison with other MIS5-4 well-documented faunas from the region.

Inimkatse blondi eesti naise peibutustest Egiptuses / Liivi Shein

Index Scriptorium Estoniae

Šein, Liivi

2006-01-01

ETVs esilinastus 23. nov. "Eesti lugude" sarjas valminud "1001 öö muinasjutt ehk eesti naiste imelised seiklused Egiptuses" : režissöör Elo Selirand : toimetaja Anne-Mari Neider : operaator Mait Mäekivi : Osakond OÜ 2006

"Mina olin siin", võib vastu hambaid saada / Andres Keil

Index Scriptorium Estoniae

Keil, Andres, 1974-

2007-01-01

Noortefilmi "Mina olin siin" võtetel. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos

Meie mees Berliinis / Lauri Kärk

Index Scriptorium Estoniae

Kärk, Lauri, 1954-

2005-01-01

Berliini 55. filmifestivalist : Eesti filmist festivalil (Euroopa noorte režissööride lühifilmidest koosnevat projekti "Kaotatud ja leitud" raamib Mait Laasi nukufilm "Gener+atio"), inglaseDavid MacKenzie mängufilmist "Pelgupaik" ("Asylum")

Kirjandus ja vabamüürlus / Paavo Matsin

Index Scriptorium Estoniae

Matsin, Paavo, 1970-

2009-01-01

Loetletakse vabamüürlastest kirjanikke (pikemalt Jules Verne'ist, Gustav Meyrinkist, Rudyard Kiplingist ja Mait Metsanurgast) ning vabamüürlikke tegelasi või motiive kasutanud kirjanikke (Lev Tolstoi, Fjodor Dostojevski, Mihhail Bulgakov, Edgar Allan Poe)

Study variation of PM-10 air pollution at Lang Meteorological Station, Hanoi Coded: CS/02/04-06

International Nuclear Information System (INIS)

Vuong Thu Bac; Dinh Thien Lam; Ngyen Thi Hong Thinh; Dang Duc Nhan; Nguyen Hao Quang; Pham Duy Hien

2003-01-01

577 air dust samples have been collected with two kinds of air samplers (2-SFU, 1-ASP) on every Wednesday and Sunday for 24 hours at both of monitoring stations (Lang - Hanoi and Lucnam - Bacgiang). PM(2.5), PM(2.5-10), PM(10) and BC concentrations in 452 air dust samples have been determined. 9032 data have been analyzed with many of different multi-elements analytical techniques (IC: 264 samples x 9 ions, PIXE: 388 samples x 15 elements, XRF: 48 samples x 8 elements, LR: 452 samples x 1 element). Over 6000 of meteorological parameters (T, Rain, WS, WD, RH...) have been collected and processed.Variations and levels of air dust concentrations and BC in Hanoi from 1998 to 2002 have been studied. PM(2.5), PM(2.5-10), PM(10) and BC concentrations and BC obviously periodically vary. They reach maximum in the winter season, especially in December and January, sometimes they reached 300-400 μg.m -3 , They reach minimum in the summer season, sometimes they went down 10 μg.m -3 on rainy days. These variations were affected by meteorological parameters. PM(2.5), PM(10) daily average concentrations in Hanoi are greater than the American air standards (PM(2.5): 65 μg.m -3 , PM(10): 150 μg.m -3 ) in many days and their yearly average concentrations are also far exceeded. Air dust pollution levels in Hanoi are higher than in developed countries and even countries in the region. BC (5.9 μg.m -3 ) concentration and Pb (0.11 μg.m -3 ) are also higher than in many countries. (VTB)

Kuidas tuua Eestisse Tiger Woods / Raul Ranne

Index Scriptorium Estoniae

Ranne, Raul

2008-01-01

Reaalselt arvestades on tõenäosus, et Eestit väisab golfistaar Tiger Woods, muidugi olematu. Teoreetiliselt on see siiski võimalik. Vestlusest Jõelähtme golfiväljakut opereeriv Estonian Golf Country Clubi presidendi Mait Schmidtiga

Ilmafilosoofia ilma filosoofiata / Jüri Rato

Index Scriptorium Estoniae

Rato, Jüri

2000-01-01

Arvustus: Hoff, Benjamin. Puhh ja Tao / tlk. Mait Talts. Tln. : Olympia, 1998 ; Hoff, Benjamin. Notsu ja Te / tlk. Paavo Kivine. Tln.: Olympia, 1999 ; Allen, Roger E. ; Allen, Stephen D. Puhh lahendab probleeme / tlk. Paavo Kivine. Tallinn : Olympia, 2000

Armastuse anatoomia / Peeter Laurits

Index Scriptorium Estoniae

Laurits, Peeter, 1962-

2007-01-01

Mängufilmist "Nuga" Peeter Sauteri ja Vaino Vahingu jutustuste motiividel : režissöör Marko Raat : peaosas Mait Malmsten : Allfilm, 2007. Samuti ka M. Raadi hiljuti valminud dokumentaalfilmist "F.F.F.F. läheb laiali"

Benefits and limitations of a multidisciplinary approach to individualized management of Cornelia de Lange syndrome and related diagnoses.

Science.gov (United States)

January, Kathleen; Conway, Laura J; Deardorff, Matthew; Harrington, Ann; Krantz, Ian D; Loomes, Kathleen; Pipan, Mary; Noon, Sarah E

2016-06-01

Given the clinical complexities of Cornelia de Lange Syndrome (CdLS), the Center for CdLS and Related Diagnoses at The Children's Hospital of Philadelphia (CHOP) and The Multidisciplinary Clinic for Adolescents and Adults at Greater Baltimore Medical Center (GBMC) were established to develop a comprehensive approach to clinical management and research issues relevant to CdLS. Little work has been done to evaluate the general utility of a multispecialty approach to patient care. Previous research demonstrates several advantages and disadvantages of multispecialty care. This research aims to better understand the benefits and limitations of a multidisciplinary clinic setting for individuals with CdLS and related diagnoses. Parents of children with CdLS and related diagnoses who have visited a multidisciplinary clinic (N = 52) and who have not visited a multidisciplinary clinic (N = 69) were surveyed to investigate their attitudes. About 90.0% of multispecialty clinic attendees indicated a preference for multidisciplinary care. However, some respondents cited a need for additional clinic services including more opportunity to meet with other specialists (N = 20), such as behavioral health, and increased information about research studies (N = 15). Travel distance and expenses often prevented families' multidisciplinary clinic attendance (N = 41 and N = 35, respectively). Despite identified limitations, these findings contribute to the evidence demonstrating the utility of a multispecialty approach to patient care. This approach ultimately has the potential to not just improve healthcare for individuals with CdLS but for those with medically complex diagnoses in general. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Algasid Henno "Mina olin siin" järgi tehtava filmi võtted

Index Scriptorium Estoniae

2007-01-01

Eile algasid noortefilmi "Mina olin siin" võtted. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos

Improviseeritud lugu ja zhanriga mäng / Donald Tomberg

Index Scriptorium Estoniae

Tomberg, Donald

2003-01-01

Eesti komöödiafilm "Vanad ja kobedad saavad jalad alla" : režissöör Rando Pettai : operaator Mait Mäekivi : näitlejad Henrik Normann, Madis Milling, Robert Gutman jt. : muusika - ansambel Genialistid : Ruut Pictures 2003

Kas meie põllunduskoolid kasvatavad peremehi või sulaseid? / Heino Luiga, Vello Vilu, Kaul Nurm ...[jt.

Index Scriptorium Estoniae

2008-01-01

Küsimusele vastab Räpina aianduskooli direktor Heino Luiga, Järvamaa kutsehariduskeskuse põllumajanduse erialade juhtiv õpetaja Vello Vilu, Eesti talupidajate keskliidu peadirektor Kaul Nurm, Olustvere teenindus- ja maamajanduskooli direktor Arnold Pastak ning maaülikooli rektor Mait Klaassen

Keskmiselt kobe vaatamine / Küllike Rooväli

Index Scriptorium Estoniae

Rooväli, Küllike, 1969-

2004-01-01

Eesti komöödiafilm "Vanad ja kobedad saavad jalad alla" : režissöör Rando Pettai : operaator Mait Mäekivi : näitlejad Henrik Normann, Madis Milling, Robert Gutman jt. : muusika - ansambel Genialistid : Ruut Pictures 2003

Giuseppe Castiglione (Lang Shining, precursor de la primera mundialización pictórico-arquitectónica

Directory of Open Access Journals (Sweden)

Manuel V. Castilla

2016-09-01

Full Text Available La obra del hermano lego jesuita Giuseppe Castiglione (nombre chino, Lang Shining, 1688-1766, desarrollada en la China Qing, no fue suficientemente conocida sino hasta el siglo xx, y se ha investigado muy poco sobre su papel precursor de la primera mundialización artística. Su aproximación a China fue primordialmente de carácter apostólico, como consecuencia de la acción misional. Esta misión estuvo basada en un proceso inculturador fundamentado, a su vez, en el intercambio de las ciencias y las artes. Este artículo pone de manifiesto el riguroso conocimiento que sobre perspectiva matemática lineal había adquirido Castiglione en Europa, y la trascendencia que tuvo en la hibridación cultural y artística en la China del siglo xviii. Su posible repercusión en manifestaciones artísticas posteriores en otros territorios constituye el tema central del trabajo. Desde el punto de vista artístico, dada su privilegiada posición en la corte imperial, el artista jesuita jugó un papel decisivo en los nuevos métodos pictórico-arquitectónicos que se desarrollaron en la dinastía Qing. Sus murales, retratos, caballos, flores y pájaros, fueron elogiados y admirados por el emperador Qianlong, y mucho tiempo después por diseñadores y pintores europeos. Al simbolismo y la sensibilidad de la pintura asiática, Castiglione añadió el misterio del ilusionismo mágico que encierra la perspectiva matemática lineal europea, que contenía la llave y el secreto del conocimiento geométrico de Lang Shining. Sin embargo, sus efectos no fueron exclusivamente artísticos, sino que en muchos casos tuvieron una vigorosa dimensión apostólica. La dimensión religiosa que presuponemos en las pinturas de los artistas jesuitas fue una herramienta esencial en el proceso de inculturación; en este sentido, G. Castiglione usó la perspectiva no sólo como una técnica que gustaba a los emperadores, y fundamentalmente al emperador Qianlong, sino también como

Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma

Directory of Open Access Journals (Sweden)

Ayako Ishimori

2017-04-01

Conclusions: For the first time, our data showed that activated NK cells, ILC1s, ILC2s, ILC3s, and MAIT cells were positively correlated with each other and may be associated with airflow limitation in patients with asthma.

Poolsajandi õnnesoovid Jaak Aaviksoole / Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar...[jt.

Index Scriptorium Estoniae

2004-01-01

Mõtteid Tartu Ülikooli rektorist tema 50. sünnipäeva puhul : Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar, Indrek Reimand, Toomas Kiho, Leelo Kriisa, Peeter Olesk, Risto Tammelo, Birute Klaas, Peeter Saari, Andrus Ansip, Mait Klaassen, Marika Kullamaa, Kaupo Bend

Lihtsamatele töödele napib ladudes ja terminalides tööjõudu / Rivo Sarapik

Index Scriptorium Estoniae

Sarapik, Rivo, 1981-

2005-01-01

Ilmunud ka: Delovõje Vedomosti 2. nov. lk. 17. Teravnemas on terminali- ja laotööliste puudus, sest lihttöödele on keeruline töötajaid leida. Kommenteerivad: Andres Leht, Annika Lootus, Mait Miller ja Margus Tammaru

Absurd on igihaljas / Vaapo Vaher

Index Scriptorium Estoniae

Vaher, Vaapo, 1945-

2006-01-01

Tutvustus: Camus, Albert. Õnnelik surm / tõlkinud Tanel Lepsoo. Tallinn : Varrak, 2005 ; Metsanurk, Mait. Kreeps / koost. Maire Liivamets. Tallinn : Eesti Raamat, 2005. (Eesti novellivara). Järg: 23. veebr., lk. 27, sisaldab Aivar Kulli kriitikakogu "Kulli pilk" (Ilmamaa, 2005) tutvustust

Sodom i Gomorra v glamurnoi miniatjure / Boris Tuch

Index Scriptorium Estoniae

Tuch, Boris, 1946-

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Kas kõik poisid tahavad endale koju Barbit? / Andris Feldmanis

Index Scriptorium Estoniae

Feldmanis, Andris, 1982-

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Geishade kataloog "Kuldrannakesel" / Kati Murutar

Index Scriptorium Estoniae

Murutar, Kati, 1967-

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Vääritu film / Linnar Priimägi

Index Scriptorium Estoniae

Priimägi, Linnar, 1954-

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Lihtsameelsed päästavad maailma / Urve Eslas

Index Scriptorium Estoniae

Eslas, Urve, 1972-

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Homme esilinastuv uus Eesti film "Kuldrannake" flirdib terrorismiteemaga / Andris Feldmanis

Index Scriptorium Estoniae

Feldmanis, Andris, 1982-

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Kilude paraad / Jaan Ruus

Index Scriptorium Estoniae

Ruus, Jaan, 1938-2017

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Vilma lõpetab leivateo / Marko Suurmägi

Index Scriptorium Estoniae

Suurmägi, Marko, 1975-

2008-01-01

Vilma emafirma Kalev Chocolate Factory juhatuse liikme Mait Nilsoni sõnul jagab Kalev jahutoodete tegemise Jõhvi ja Viljandi ettevõtte vahel nii, et leiba ja saia hakatakse küpsetama Jõhvis ning Viljandisse koondub tortide, kookide ja jahusegude valmistamine. Lisa: Ajalugu

Eesti teadlaste artikkel juutide põlvnemisest jõudis tippajakirja / Marju Himma

Index Scriptorium Estoniae

Himma, Marju

2010-01-01

Eesti ja Iisraeli teadlaste rühm uuris juutide geneetilist sarnasust üle maailma. Artikkel avaldati rahvusvahelises teadusajakirjas Nature. Uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayevi, Mait Metspalu ja Richard Villems

Delta Plaza kohvik = The Delta Plaza Café / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Pärnu mnt. 141 asuva kohviku Delta Plaza sisekujundusest. Sisearhitektid Tiiu Truus ja Marja Viltrop (Stuudio Truus OÜ). Hoone arhitektid Jüri Okas ja Marika Lõoke (AB J. Okas & M. Lõoke). Žürii liikme Mait Summataveti arvamus kohvikust

Novos registros de Eunotia Ehrenberg (Eunotiaceae-Bacillariophyta para o Estado do Rio Grande do Sul e Brasil New reports of Eunotia Ehrenberg (Eunotiaceae-Bacillariophyta for Rio Grande do Sul State and Brazil

Directory of Open Access Journals (Sweden)

Aline Brugalli Bicca

2009-06-01

Full Text Available O trabalho tem como objetivo apresentar as características morfológicas, e/ou estruturais e métricas de 12 espécies de Eunotia (E. batavica A. Berg, E. deficiens Metz., Lange-Bert & García-Rodr., E. genuflexa Nörpel-Sch., E. hepaticola Lang-Bert. & Wydrz., E. herzogii Krasske, E. mucophila (Lange-Bert., Nörpel-Sch. & Alles Lange-Bert., E. pileus Ehr., E. pirla Carter & Flower, E. schwabei Krasske, E. subarcuatoides Alles, Nörpel-Sch. & Lange-Bert., E. transfuga Metz. & Lange-Bert. e E. yanomami Metz. & Lange-Bert. encontradas nas áreas da Lagoa do Casamento e dos Butiazais de Tapes, entre as coordenadas 30º10'-30º40'S e 50º30'-51º30'W, na Planície Costeira do Rio Grande do Sul. São incluídos comentários sobre a distribuição e os ambientes onde os táxons foram encontrados.This paper presents the morphological and/or structural and mensurable characteristics of 12 Eunotia species (E. batavica A. Berg, E. deficiens Metz., Lange-Bert. & García-Rodr., E. genuflexa Nörpel-Sch., E. hepaticola Lang-Bert. & Wydrz., E. herzogii Krasske, E. mucophila (Lange-Bert., Nörpel-Sch. & Alles Lange-Bert., E. pileus Ehr., E. pirla Carter & Flower, E. schwabei Krasske, E. subarcuatoides Alles, Nörpel-Sch. & Lange-Bert., E. transfuga Metz. & Lange-Bert. and E. yanomami Metz. & Lange-Bert. found in the Lagoa do Casamento and Butiazais de Tapes areas, between 30º10'-30º40'S and 50º30'-51º30'W, on the Rio Grande do Sul State Coastal Plain. Comments on distribution and habitats where the taxons are found are included.

L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome.

Science.gov (United States)

Xu, Baoshan; Sowa, Nenja; Cardenas, Maria E; Gerton, Jennifer L

2015-03-15

Cohesinopathies are human genetic disorders that include Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) and are characterized by defects in limb and craniofacial development as well as mental retardation. The developmental phenotypes of CdLS and other cohesinopathies suggest that mutations in the structure and regulation of the cohesin complex during embryogenesis interfere with gene regulation. In a previous project, we showed that RBS was associated with highly fragmented nucleoli and defects in both ribosome biogenesis and protein translation. l-leucine stimulation of the mTOR pathway partially rescued translation in human RBS cells and development in zebrafish models of RBS. In this study, we investigate protein translation in zebrafish models of CdLS. Our results show that phosphorylation of RPS6 as well as 4E-binding protein 1 (4EBP1) was reduced in nipbla/b, rad21 and smc3-morphant embryos, a pattern indicating reduced translation. Moreover, protein biosynthesis and rRNA production were decreased in the cohesin morphant embryo cells. l-leucine partly rescued protein synthesis and rRNA production in the cohesin morphants and partially restored phosphorylation of RPS6 and 4EBP1. Concomitantly, l-leucine treatment partially improved cohesinopathy embryo development including the formation of craniofacial cartilage. Interestingly, we observed that alpha-ketoisocaproate (α-KIC), which is a keto derivative of leucine, also partially rescued the development of rad21 and nipbla/b morphants by boosting mTOR-dependent translation. In summary, our results suggest that cohesinopathies are caused in part by defective protein synthesis, and stimulation of the mTOR pathway through l-leucine or its metabolite α-KIC can partially rescue development in zebrafish models for CdLS. © The Author 2014. Published by Oxford University Press.

101 riigikogulast said valijalt ehmatava liputervituse / Tuuli Koch

Index Scriptorium Estoniae

Koch, Tuuli

2006-01-01

Ilmunud ka: Postimees : na russkom jazõke 4. sept. lk. 4. Valija Tiina Talts saatis presidendivalimiste esimese päeva hommikul parlamendiliikmetele kirja, mille juurde oli ümber disainitud Eesti lipp. Vastused saatsid neli saadikut, nende hulgas Mait Klaassen, Jaak Allik, Janno Reiljan

Nõmme Lunastaja kirik = The Saviour's Lutheran Church in Nõmme / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Õie 10 asuva kirikuhoone (arhitekt Robert Natus, 1932) restaureerimisest. Arhitekt Fredi-Armand Tomps, sisearhitekt Anne Koppel, ehitusjärelevalve: Rein Joller, ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang EK arhitektuuri sihtkapitali 2009. a. restaureerimispreemia pälvinud hoonele

Toompea komandandimaja = The Commandant's House in Toompea / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Toompea 1 asuva hoone restaureerimisest. Arhitekt Raul Vaiksoo, kaasautor Kristo Vaiksoo (Raul Vaiksoo Arhitektuuribüroo), sisearhitektid Priit Põldme, Rita Rahu (SAB Joonprojekt), Raul Vaiksoo, ajaloolased Raul Vaiksoo, Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

Võtme ja riiviga tantsufilm / Kristiina Garancis

Index Scriptorium Estoniae

Garancis, Kristiina, 1969-

2005-01-01

Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island 2005

Rohkem kui lihtsalt tantsufilm / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2005-01-01

Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island 2005

Paugub püstol, lendavad kilud / Olev Remsu

Index Scriptorium Estoniae

Remsu, Olev, 1947-

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions. Pikemalt stsenaariumist

Superorgaaniline animatsioon / Jan Kaus

Index Scriptorium Estoniae

Kaus, Jan, 1971-

2006-01-01

Eesti uuemast animafilmist. Põhjalikumalt on käsitletud 2005.a. eesti animatsioonikunsti tippteosena Mait Laasi filmi "Generatio". Lisatud lühiandmed M. Laasi kohta, samuti kuue riigi koostööfilmi "Kaotatud ja leitud" kohta, mille lühifilmid seob tervikuks "Generatio"

Meie näitekirjandus aastal 1931 / Ants Oras

Index Scriptorium Estoniae

Oras, Ants, 1900-1982

2009-01-01

Ülevaade 1931. aasta eesti näitekirjandusest. Pikemalt käsitletakse: Mait Metsanurk "Mässuvaim, ehk, Agulirahvas läheb ajalukku", Hugo Raudsepp "Põrunud aru õnnistus", Agnes Taar "Emake maamuld", Aleksander Antson "Töölise tütar", Artur Adson "Neli kuningat"

Näitleja Anti Reinthal : "Kui sa just surnud ei ole, siis mängid lõpuni!" / Katrin Rohtla

Index Scriptorium Estoniae

Rohtla, Katrin, 1966-

2007-01-01

Viinistu kunstimuuseumis etenduva Eesti Draamateatri suvelavastuse "Sürrealistid" 30. juuni etenduses vigastas näitleja raskelt oma reielihast kuid mängis lõpuni. Lisaks Mait Malmsteni kommentaar "Malmsten : "Esimene vaatus mängiti fantaasia abil" ja vaataja arvamus : "Publiku pettis ära"

Arhitektuurivõistlused 2008 / Mait Väljas

Index Scriptorium Estoniae

Väljas, Mait

2008-01-01

Võistluste tulemused: Pekingi saatkonnahoone: I preemia - A. Põime, L. Põime, L. Vaimel; Riia saatkonnahoone: I - L.-K. Stöör, Ü.-T. Stöör, H. Urb; Eesti Kunstiakadeemia uus õppehoone: I - SEA + Effekt (Taani); Eesti Maaülikooli Kreutzwaldi 5 õppehoone juurdeehitis: I - P. Loo, J. Skolimowski, L. Vene, K. Kruuse (KAMP Arhitektid); TÜ Viljandi Kultuuriakadeemia loomeinkubaatori ja lavakunstide õppehoone: I - S. Vallner, H. Urb, I. Peil, H. Lass, S.-M. Mändmaa (Kavakava); Tamula järve ranna-ala mahuline planeering: I - K. Enno, L. Luhse, M. Zeleznova, R. Ailt (K. Enno Arhitektuuribüroo); Tartu pärmivabriku kvartali arhitektuurivõistlus: võidutöö - Atelier Thomas Pucher / Bramberger Architects (Austria); Paldiski mnt. 50 kinnistu ja lähiala: I-II - T. Laigu, K. Ojaliiv, M. Rass, A. Uukado (QP Arhitektid); maastikuarhitektuuri võistlus "Eesti Maaülikooli Tähtvere linnaku välialad": I - H. Runnel, T. Ong; Tartu rahu tähisala kujundus: I - M. Kinks, K. Süda; Veneetsia XI rahvusvahelise arhitektuuribiennaali ideekavandi võistlus: I - M. Kask, R. Lõoke, N. Külm; aasta betoonehitis 2007 - Puurmani kaarsild, konstruktorid S. Idnurm, J. Idnurm; Eesti parim puitehitis 2008: eramu Loobul - R. Vaiksoo; võistluse "Eramu 2006-2007" peapreemia: villa Paldiskis - S. Vallner, I. Peil

Birma - otsekui retk minevikku / Mait Talts

Index Scriptorium Estoniae

Talts, Mait, 1964-

2011-01-01

Reisist Birmasse, tänapäevase nimega Myanmari, mida Eestiga seovad sinna maetud "Eestimaa budistlikud peapiiskopid" Karl A.M. Tõnisson-Tennisons (Vend Vahindra, 1883-1962) ja Friedrich Voldemar Lustig (Ashin Ananda, 1912-1989)

"Having fun with the long take"

DEFF Research Database (Denmark)

Nielsen, Jakob Isak

2007-01-01

Den lange uklippede indstilling rummer mange forskelligartede iscenesættelsesstrategier. Denne artikel føjer et ekstra kapitel til den efterhånden lange historie om den lange indstilling ved at undersøge en anvendelse, som er underbelyst i litteraturen: den lange indstilling som komisk henvendels...

Baltika büroo = The Baltika Offices / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Veerenni 24 asuvast Baltika büroost. Arhitektuur, bürooruumide kujundus: AB Studio 3, Kolm Pluss Üks Arhitektid. Žürii liige Mait Summatavet žürii hinnangust EK arhitektuuri sihtkapitali 2009. a. sisearhitektuuri preemia pälvinud bürooruumidele

Jüri Sillart alustab uue mängufilmi võtteid / Mart Rummo

Index Scriptorium Estoniae

Rummo, Mart

2005-01-01

J. Sillart alustas Maardu mõisas uues mängufilmi "Kuldrannake" võtteid. Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik sen oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsent Kristian Taska, tootjafirmaks Taska Productions

Kuldrannakese virvatuled / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo, 1958-

2006-01-01

Jüri Sillarti mängufilmi "Kuldrannake" eilse esilinastuse puhul. Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik sen oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

Eesti osaleb suurejoonelises filmiprojektis

Index Scriptorium Estoniae

pPIK mare 2010

2004-01-01

Filmiprojekt tööpealkirjaga "Generation", mis on plaanitud täispikaks mängufilmilaadseks filmiks. Tegemisse on kaasatud kuus noort režissööri Ida-Euroopast. Eestit esindab animafilmide režissöör Mait Laas, kes teeb valmivale filmile raamjutustuse

Loomad räägivad sel korral eesti keeles / Jaanus Noormets

Index Scriptorium Estoniae

Noormets, Jaanus

2008-01-01

Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (Madagascar: Escape 2 Africa), mis jõuab Eesti kinodesse erinevalt filmisarja esimesest osast eesti keelde dubleerituna (loomtegelastele on oma hääle laenanud Karol Kuntsel, Andero Ermel, Evelin Pang, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik jt)

Vanglamüüride vahel võeti üles tantsufilmi / Villu Päärt

Index Scriptorium Estoniae

Päärt, Villu, 1972-

2005-01-01

ETV-l valmib koos EFS-i ja Estinfilmiga kultuurikanali ARTE tellimusel tantsufilm "Teine" : režissöör Rene Vilbre : stsenarist Teet Kask : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtetest Tartu vanglas

Lang Lang: From child prodigy to Carregie Hall

Institute of Scientific and Technical Information of China (English)

Tricia Carswell

2004-01-01

<正>As a child, I had three wishes: to have my own bicycle, to take figure-skating lessons, and to play piano. As a young mother of 26,I finally bought a bicycle which I happily rode up and down our farm laneway. At 34, my first lesson with a professional skating teacher was also my last when I fell on the ice and popped an instant bump the size of an egg on the back of my head. To my chagrin, the only keyboard I ever mastered was that of the typewriter/computer.

Kinetics of fibrilar aggregation of food proteins

NARCIS (Netherlands)

Arnaudov, L.N.

2005-01-01

In this thesis we study the kinetics of fibrilar aggregation of two model proteins widely used in the food industry -lang=EN-GB style='font-family:Symbol'>blang=EN-GB>-lactoglobulin (lang=EN-GB style='font-family:Symbol'>blang=EN-GB>-lg) and hen

A Physics and Tabulated Chemistry Based Compression Ignition Combustion Model: from Chemistry Limited to Mixing Limited Combustion Modes Un modèle de combustion à allumage par compression basé sur la physique et la chimie tabulée : des modes de combustion contrôlés par la chimie jusqu’aux modes contrôlés par le mélange

Directory of Open Access Journals (Sweden)

Bordet N.

2011-11-01

experimental measurements carried out on a 2 liter Renault Diesel engine and good agreements are found. Ce papier présente une nouvelle approche 0D phénoménologique pour prédire le déroulement de la combustion dans les moteurs Diesel à injection directe pour toutes les conditions d’utilisation usuelles. Le but de ce travail est de développer une approche physique en vue d’améliorer la prédiction de la pression cylindre et du dégagement d’énergie, avec un nombre minimum d’essais nécessaires à la calibration. Les contributions principales de cette étude sont la modélisation de la phase de pré-mélange de la combustion et une extension du modèle pour les stratégies d’injections multiples. Dans ce modèle, le taux de dégagement d’énergie dû à la combustion pour la phase pré-mélangée est relié à un taux de réaction moyen du carburant. Ce taux de réaction moyen de carburant est évalué à l’aide d’une approche basée sur un taux de réaction local de carburant tabulé et la détermination d’une fonction de densité de probabilité (PDF de la fraction de mélange (Z. Cette PDF permet de prendre en compte la distribution de richesse existante dans la zone pré-mélangée. L’allure de cette PDF présumée est une β-fonction standardisée. Les fluctuations de la fraction de mélange sont décrites avec une équation de transport pour la variance de Z. La définition standard de la fraction de mélange, établie dans le cas de flammes de diffusion, est ici adaptée à une combustion pré-mélangée de type Diesel pour décrire l’inhomogénéité de la richesse dans le volume de contrôle. La chimie détaillée est décrite au travers de la tabulation du taux de réaction relatif à la flamme principale et du délai d’auto-inflammation relatif à la flamme froide, ces tabulations sont fonction de la variable d’avancement c, du taux de gaz brûlé ainsi que des grandeurs thermodynamiques telles que la température et la pression. Le

Jõgeva bussijaam sai liimpuidu kasutamise eripreemia

Index Scriptorium Estoniae

2009-01-01

Konkursil Eesti Parim Puitehitis 2009 sai liimpuidu kasutamise eripreemia Jõgeva bussijaam, arhitektid Andres Lunge ja Mait Lauri firmast Lunge & Co OÜst. Peapreemia pälvis suvila Jõelähtmel, arhitekt Sten Ader büroost SKAD Arhitektid. Loetletud ka teisi auhinnalistele kohtadele tulnud töid

Tartu kalendritootja investeeris uude tehasesse 100 miljonit / Kadrin Karner

Index Scriptorium Estoniae

Karner, Kadrin

2008-01-01

Ilmunud ka: Delovõje Vedomosti 24. sept. lk. 5. Tartus avatud Ajasto Diary Groupi kalendritehasesse investeeriti üle 100 miljoni krooni, mille tasuvuspiiriks loeb ettevõte umbes kümme aastat. Vt. samas: Mis on mis: Ajasto Diary Group; Kommenteerivad: Mait Puusepp, Andras Metsa, Kadrin Karner

Vanglarahvas tantsib Euroopasse / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2005-01-01

Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas

Mahtra muuseumis ja Juuru vallas käisid auväärsed külalised / Tiia Truu

Index Scriptorium Estoniae

Truu, Tiia, 1948-

2009-01-01

1. juulil 2009 külastasid Mahtra talurahvamuuseumi Mahtra sõja mälestusmärgi looja Johannes Tuti lesk Leili Tutt ja nende poeg Mait Tutt Rootsist ning tütar Eha Dascenzo USA-st Swanscast, nendega koos oli J. Tuti vennatütar Maie Vikat

Tantsuime: märjaks nutetud Märt Agu saab 8000 uut sõpra / Märt Agu ; intervjueerinud Rein Sikk

Index Scriptorium Estoniae

Agu, Märt, 1980-

2011-01-01

11. Noorte tantsupeo "Maa ja ilm" üldjuht ja Tallinna Tantsuakadeemia kunstiline juht Märt Agu Tallinna lauluväljakul toimuvast tantsupeost, ülevaatustest, eesti meeste rahvatantsust, oma isast Mait Agust, tema tantsust "Põhjamaa", tantsuõpetaja elukutsest, eesti tantsust, Tallinna Tantsuakadeemiast. Andmeid Märt Agu loomingu kohta

Võigas ja seletamatu tsirkus : kaasaja ja alateadvuse pained "Agent Sinikaelas" / Sven Vabar

Index Scriptorium Estoniae

Vabar, Sven

2002-01-01

Mängufilm "Agent Sinikael" : stsenaristid Marko Raat ja Andres Maimik : režissöör Marko Raat : operaator Arko Okk : helilooja Janek Murd : kunstnikud Margus Tammik ja Jaana Jüris : nimiosas Mait Malmsten : produtsendid Peeter Urbla ja Veiko Õunapuu : Exitfilm ja Suhkur Film, 2002

Vikergallup : eesti kirjandus 2012 / Vahur Afanasjev, Joanna Ellmann, Peeter Helme ... [jt.

Index Scriptorium Estoniae

2013-01-01

Erinevate kriitikute arvamus 2012. aastal Eestis ilmunud nüüdiskirjandusest. Aasta parimaks uudisteoseks nimetati Peeter Sauteri "Märkmeid vaeste kirjanike majast", parimaks debüüdiks Mait Vaigu luulekogu "Kõigil on alati õigus", parimaks tõlkeraamatuks Georges Pereci romaan "Elu, kasutusjuhend" ja Pentti Saarikoski koondkogu "Luuletused"

Nick Park pani Wallace'ile ja Gromitile libaküüliku needuse / Mart Rummo

Index Scriptorium Estoniae

Rummo, Mart

2005-01-01

Uus animafilm "Wallace ja Gromit : Libaküüliku needus" ("Wallace & Gromit : The Curse of the Were-Rabbit") : režissöör Nick Park : Suurbritannia 2005. Selle loojast ja tema loometeest. Lisatud : Nick Park (filmograafia, auhindu), "Teised Nick Parkist" (Lauri Kaare, Mait Laas, Riho Unt)

Kuus uut Eesti filmi korraga ekraanil / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo

1998-01-01

21. mail esilinastuvad kinos Sõprus 'Just märried', rezh. Peep Pedmanson; 'Päevavalgus', rezh. Mait Laas; 'Primavera', rezh. Riho Unt ja Hardi Volmer; 'Vares ja hiired', rezh. Priit Tender ja Mikk Rand; 'Bermuda', rezh. Ülo Pikkov; 'Tom ja Fluffy', rezh. Janno Põldma ja Heiki Ernits

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Lifescience Database Archive (English)

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GOLD - MicrobeDB.jp | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - TP Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

RMOS Contents - RMOS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Protein structure image - ConfC | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - Dicty_cDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - Gene Name Thesaurus | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - Gene Name Thesaurus | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - RED II INAHO | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - ClEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Taxonomy Icon Images (PNG format) - Taxonomy Icon | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - Dicty_cDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Designation of organism group - Gclust Server | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

GPCR sequence information - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - RED II INAHO | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Model Structure Thumbnail - SAHG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - DB-SPIRE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - JSNP | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - RGP gmap2000 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - ChIP-Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - Society Catalog | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - Togo Picture Gallery | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - The Rice Growth Monitoring for The Phenotypic Functional Analysis | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

The list of growth image files - The Rice Growth Monitoring for The Phenotypic Functional Analysis | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - AcEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Insert size of YAC clones - RGP physicalmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - Open TG-GATEs Pathological Image Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

5'-end sequences of budding yeast full-length cDNA clones - Budding yeast cDNA sequencing project | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - RGP physicalmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Experiments list - DGBY | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - GETDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - Nikkaji-InChI Mapping Table | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - RGP estmap2001 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - dbQSNP | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - RGP gmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - RGP physicalmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Mascot search results - CREATE portal | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - Budding yeast cDNA sequencing project | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Update History of This Database - TMBETA-GENOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - Open TG-GATEs Pathological Image Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Transcriptome data - Air-drying stress - DGBY | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Supplementary Data - fRNAdb | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available search(/contents-en/) != -1 || url.search(/index-e.html/) != -1 ) { document.getElementById(lang).innerHTML=.../) != -1 ) { url = url.replace(-e.html,.html); document.getElementById(lang).innerHTML=[ Japanese |...en/,/jp/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if ( url.search(//contents...//) != -1 ) { url = url.replace(/contents/,/contents-en/); document.getElementById(lang).innerHTML=[ Japanes...e(/contents-en/,/contents/); document.getElementById(lang).innerHTML=[ Japanese | English ]; } else if( url.

Download - SKIP Stemcell Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Image of Arabidopsis phenotype - Arabidopsis Phenome Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Update History of This Database - CREATE portal | LSDB Archive [Life Science Database Archive metadata

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Download - MicrobeDB.jp | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Download - RGP caps | LSDB Archive [Life Science Database Archive metadata

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Update History of This Database - RGP caps | LSDB Archive [Life Science Database Archive metadata

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Download - CREATE portal | LSDB Archive [Life Science Database Archive metadata

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Download - RGP estmap2001 | LSDB Archive [Life Science Database Archive metadata

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Update History of This Database - RGP gmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Sõpruses esilinastub Eesti-Islandi tantsufilm

Index Scriptorium Estoniae

2005-01-01

10. novembril esilinastub rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas

Wow! Tallinn! / Jaak Rand

Index Scriptorium Estoniae

Rand, Jaak

2006-01-01

Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions. Lisatud Jüri Sillarti filmograafia lk. 83

Nirvaana, susla ja internet / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo, 1958-

2000-01-01

Kolm stuudio Nukufilm uut nukufilmi : "Saamueli Internet" : Stsenarist Andrus Kivirähk : režissöör ja kunstnik Riho Unt; "Teekond Nirvaanasse" : Stsenarist, režissöör ja kunstnik Mait Laas; "Eilne vedur" : režissöörid Mikk Rand ja Kalju Kivi

Ilma tahtmata ja teadmata paradiisi ehk Arhetüüp eesti moodi / Rein Tootma

Index Scriptorium Estoniae

Tootma, Rein

2006-01-01

Lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005

Ära kosi Pikka: Pikk läheb pingile magama / Meelis Oidsalu

Index Scriptorium Estoniae

Oidsalu, Meelis, 1978-

2010-01-01

Kevadel lavakunstikooli lõpetavate tudengite lavastusest "Pikk pink" , mis koosneb kuuest lühiloost - Mait Jooritsa "Kantani padi", Kristjan Üksküla "Jääger" ja "Albioni tütar", Roland Laosi "Genees ja katastroof", Hendrik Toompere jun. "Karupoeg Puhh" ja Kerttu Moppeli " Leib!". Esietendus 23. nov. Hobuveskis

Lavaka lõpetajate pink on pikk / Tiiu Laks

Index Scriptorium Estoniae

Laks, Tiiu, 1984-

2009-01-01

Kevadel lavakunstikooli lõpetavate tudengite lavastusest "Pikk pink" , mis koosneb kuuest lühiloost - Mait Jooritsa "Kantani padi", Kristjan Üksküla "Jääger" ja "Albioni tütar", Roland Laosi "Genees ja katastroof", Hendrik Toompere jun. jun. "Karupoeg Puhh" ja Kerttu Moppeli " Leib!". Etendused toimuvad Hobuveskis

Eesti animafilmid Ottawas / M. L.

Index Scriptorium Estoniae

M. L.

2006-01-01

Ottawa rahvusvahelisel animafilmifestivalil 20.-24. sept. võistlesid Eesti poolt Mati Küti "Une instituut" ja "Vulcain.Cricet", Priit Tenderi "Sõnum naabritele", Ülo Pikkovi "Elu maitse" ja Mait Laasi "Generatsioon". Eesti auhindu ei saanud. Peaauhind täispika animatsiooni eest läks inglasele Phil Mulloy'le filmi "Christied" eest

"Riigikogu hoone 90" = "Estonian parliament building 90" / Janno Roos, Andres Labi

Index Scriptorium Estoniae

Roos, Janno, 1976-

2013-01-01

Eesti Sisearhitektide Liidu 2012. aasta näituse kujunduse preemia pälvinud näitusest (Lossiplats 1A). Kujunduse autorid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Mait Väljas. Graafiline disain: Identity. Sisearhitekti ja ESLi aastapreemiate žürii liikme Mari Kurismaa ning arhitektuuriajaloolase Leele Välja arvamused

Väikeelamine suureks - normaalpere konteinersüsteemis = Small living space made bigger - container system for a typical family

Index Scriptorium Estoniae

2009-01-01

Tutvustatakse Tallinna Tehnikakõrgkooli Arhitektuuri Instituudi arhitektuuri eriala üliõpilaste töid teemal "Väikeelamine suureks - normaalpere konteinersüsteemis". Idee: rahuldada ühesuuruste "konteinerite" baasil ehitatud torn- või ridamajadega väikekorterite nõudlust. Juhendaja: sisearhitekt Mait Summatavet (lk. 60 andmeid M. Summataveti elu ja loomingu kohta)

Tantsufilm "Teine" ETV-s

Index Scriptorium Estoniae

2005-01-01

Täna on ETV-s rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas

Paariselamu Luccas = Duplex House in Lucca / Indrek Allmann

Index Scriptorium Estoniae

Allmann, Indrek, 1972-

2001-01-01

Projekteerija: Arhitektuuribüroo Kolde Grupp. Arhitekt Indrek Allmann, konstruktorid Andres Läänesaar, Aldur Parts, Valdo Jaanisoo, Mait Mets. Hoone asub panga ülemise tasandi kõrgusel õhus, pangapealsega on ühendatud terrassi abil, ligipääs alumisel tasandil. Projekt 1999, valmis 2001. 5 ill.: põhiplaan, vaated

A novel hybrid evidential belief function-based fuzzy logic model in spatial prediction of rainfall-induced shallow landslides in the Lang Son city area (Vietnam

Directory of Open Access Journals (Sweden)

Dieu Tien Bui

2015-04-01

Full Text Available The main objective of this study is to investigate potential application of an integrated evidential belief function (EBF-based fuzzy logic model for spatial prediction of rainfall-induced shallow landslides in the Lang Son city area (Vietnam. First, a landslide inventory map was constructed from various sources. Then the landslide inventory map was randomly partitioned as a ratio of 70/30 for training and validation of the models, respectively. Second, six landslide conditioning factors (slope angle, slope aspect, lithology, distance to faults, soil type, land use were prepared and fuzzy membership values for these factors classes were estimated using the EBF. Subsequently, fuzzy operators were used to generate landslide susceptibility maps. Finally, the susceptibility maps were validated and compared using the validation dataset. The results show that the lowest prediction capability is the fuzzy SUM (76.6%. The prediction capability is almost the same for the fuzzy PRODUCT and fuzzy GAMMA models (79.6%. Compared to the frequency-ratio based fuzzy logic models, the EBF-based fuzzy logic models showed better result in both the success rate and prediction rate. The results from this study may be useful for local planner in areas prone to landslides. The modelling approach can be applied for other areas.

Determination of Optimal Double Sampling Plan using Genetic Algorithm

Directory of Open Access Journals (Sweden)

Sampath Sundaram

2012-03-01

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The Utility of the Metacognitive Awareness Inventory for Teachers among In-Service Teachers

Science.gov (United States)

Kallio, Heli; Virta, Kalle; Kallio, Manne; Virta, Arja; Hjardemaal, Finn Rudolf; Sandven, Jostein

2017-01-01

The purpose of the present study is to explore the utility of the compressed version of the Metacognitive Awareness Inventory for Teachers (MAIT-18) among in-service teachers. Knowledge of teachers' awareness of metacognition is required to support students' self-regulation, with the aim of establishing modern learning methods and life-long…

432 püksipaari Riia kongresside palee fassaadil / Lauri Kärk

Index Scriptorium Estoniae

Kärk, Lauri, 1954-

2000-01-01

Filmifestivalil "Arsenals" sai parima režissööri kujukese Mait Laas nukufilmi "Teekond Nirvaanasse" eest, teise koha preemia Valentin Kuigi mängufilm "Lurjus" ja Riho Undi nukufilm "Saamuel internetis". Peaauhinna andis loos shoti naisrežissööri Lynne Ramsay mängufilmile "Rotipüüdja" ("Ratcatcher")

Sinikael jätab jälgi / Tristan Priimägi

Index Scriptorium Estoniae

Priimägi, Tristan, 1976-

2002-01-01

Mängufilm "Agent Sinikael" : stsenaristid Marko Raat ja Andres Maimik : režissöör Marko Raat : operaator Arko Okk : helilooja Janek Murd : kunstnikud Margus Tammik ja Jaana Jüris : nimiosas Mait Malmsten : produtsendid Peeter Urbla ja Veiko Õunapuu : Exitfilm ja Suhkur Film, 2002. Lisatud Marko Raati filmograafia lk. 103

Lastemuuseum Miia-Milla-Manda = The Miia-Milla-Manda Children's Museum / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Koidula 21A asuva hoone restaureerimisest, lastemuuseumi sisekujundusest. Kadrioru Lastepargi paviljoni (arhitekt Villem Seidra, 1937) renoveerimisprojekti tegi arhitekt Katrin Etverk, sisearhitektid ja ekspositsiooni kujundus: Maile Grünberg, Eliina Grünberg (Grünberg oü). Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

Tudengite nappus seab kõrgkoolid raskustesse / Madis Filippov

Index Scriptorium Estoniae

Filippov, Madis

2008-01-01

Gümnasistide arvu vähenemine nõuab kõrgkoolide töö ümberhindamist. Arvamust avaldavad Tallinna Ülikooli rektor Rein Raud, Tartu Ülikooli rektor Alar Karis, Eesti Maaülikooli rektor Mait Klaassen, Euroülikooli rektor Jüri Martin, Estonian Business Schooli rektor Peeter Kross ja haridusminister Tõnis Lukas

Karmid mängud / Kristel Raesaar

Index Scriptorium Estoniae

Raesaar, Kristel

2000-01-01

Tüli puiduärimehega maksis Hansapangale üle 100 miljoni. Lisa: ühed faktid, mitu tõlgendust - Hansapanga kreedidirektor Aivar Rehe, ECT tegevjuhi Arvi Schilfi ja laenu varjamises süüdistatud Hansapanga endise väliskaubanduse finantseerimise osak. juhataja Mait Kolditsa nägemus ECT laenuraha kadumisega seotud sündmustest

What makes “a mental illness?” What makes “a new mental illness”?: The cases of solastalgia and hubris syndrome.

Directory of Open Access Journals (Sweden)

Seamus P MacSuibhne

2009-11-01

Full Text Available

lang="RU">What is a “mental illness”? What is an “illness”? What does the description and classification of “mental illnesses” actually involve, and is the description of “new” mental illnesses description of actually existing entities, or the creation of them?  “Solastalgia” is a neologism, invented by the Australian environmental philosopher Glenn Albrecht, to give greater meaning and clarity to psychological distress caused by environmental change (Albrecht et al 2007 The concept received some coverage in the international mass media in late 2007 (Thompson, 2007 Much of this described solastalgia as “a new concept in mental illness”, a description endorsed by Albrecht himself. The doctor and former British Foreign Secretary, Lord Owen, has coined the phrase “hubris syndrome” to describe the mindset of prime ministers and presidents whose behaviour is characterised by reckless, hubristic belief in their own rightness. This lang="EN-GB">paper lang="RU">uses lang="EN-GB">both lang="RU">the concept of solastalgia and the related concepts Albrecht posited of psychoterratic and somaterratic illnesseslang="EN-GB"> and hubris syndromelang="RU"> as a starting point to explore issues around the meaning of mental illness, and what it means to describe and classify mental illness.lang

An Inference Language for Imaging

DEFF Research Database (Denmark)

Pedemonte, Stefano; Catana, Ciprian; Van Leemput, Koen

2014-01-01

We introduce iLang, a language and software framework for probabilistic inference. The iLang framework enables the definition of directed and undirected probabilistic graphical models and the automated synthesis of high performance inference algorithms for imaging applications. The iLang framewor...

Saagu valgus / Karin Tarto

Index Scriptorium Estoniae

Paulus, Karin, 1975-

1998-01-01

Eesti valgustikujundajatest ja valgustitest. Kas eesti disaineritel on õnnestunud leida oma nišš lambiletil. Tootjatest : OÜ "Raunto", AS "Titanus" (disaineriks Eestis elav rootslane Renni Par)-, Norrast pärineva kontserni "Glamox" tehasest Keilas, "Estoplastist" (disainerid Martin Pärn, Raido Laasing), AS "Steel Line". Valgustikujundajatest Tarmo Luisust, Aleksander Jakovlevist, Raivo Pristolist, Mait Summatavetist, Tõnis Vellamast

Põlvas näeb Ove Mustingu filmi / Tiia Allas

Index Scriptorium Estoniae

Allas, Tiia

2006-01-01

8. jaan. linastub Põlva kultuurikeskuses lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005

Multifilm kui tõsine asi / Marko Mägi

Index Scriptorium Estoniae

Mägi, Marko

1998-01-01

Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

Eesti animafilme igale maitsele / Sulev Teinemaa

Index Scriptorium Estoniae

Teinemaa, Sulev, 1947-

1998-01-01

Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

Aimdusi tsivilisatsioonist / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo, 1958-

1998-01-01

Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

Animaalselt ja humaanselt / Karlo Funk

Index Scriptorium Estoniae

Funk, Karlo, 1971-

1998-01-01

Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

Herbert Johansoni eeskujulikud koolimajad / Mait Väljas

Index Scriptorium Estoniae

Väljas, Mait

2010-01-01

Eesti arhitektuurimuuseumis eksponeeritava Herbert Johansoni (1884–1964) ja Eugen Habermanni (1884–1944) juubelinäituse taustal on kohane rääkida koolimajadest. Johansoni kontol on suur osa Tallinna sõdadevahelistest koolimajadest, kaks lasteaeda ja üks kutsekool

MAIT cells: new guardians of the liver

OpenAIRE

Kurioka, Ayako; Walker, Lucy J; Klenerman, Paul; Willberg, Christian B

2016-01-01

The liver is an important immunological organ that remains sterile and tolerogenic in homeostasis, despite continual exposure to non-self food and microbial-derived products from the gut. However, where intestinal mucosal defenses are breached or in the presence of a systemic infection, the liver acts as a second 'firewall', because of its enrichment with innate effector cells able to rapidly respond to infections or tissue dysregulation. One of the largest populations of T cells within the h...

Educations in Ethnic Violence: Identity, Educational Bubbles, and Resource Mobilization

Science.gov (United States)

Lange, Matthew

2011-01-01

In "Educations in Ethnic Violence", Matthew Lange explores the effects education has on ethnic violence. Lange contradicts the widely-held belief that education promotes peace and tolerance. Rather, Lange finds that education commonly contributes to aggression, especially in environments with ethnic divisions, limited resources, and…

L’utilisation du prémélange de monensin chez les vaches laitières : un suivi simple et essentiel pour s’assurer d’une utilisation adéquate

Science.gov (United States)

Dubuc, Jocelyn; Baril, Jean; DesCôteaux, Luc

2009-01-01

Le prémélange de monensin est utilisé fréquemment sur les fermes laitières canadiennes. L’ingrédient actif de ce produit est le monensin sodique. Bien que son utilisation chez les vaches laitières soit sécuritaire, des cas de surdose ont été rapportés à la suite de consommation de niveaux de monensin plus élevés que ceux recommandés. Un suivi hebdomadaire du pourcentage de matières grasses du réservoir de lait de la ferme devrait être fait de routine suite à la livraison d’aliment médicamenteux contenant du monensin pour détecter rapidement les situations de surdose. L’observation d’une baisse soudaine de la consommation volontaire de matière sèche et l’apparition de diarrhée dans un troupeau sont d’autres signes cliniques de surdose de monensin. Une détection rapide de ces cas permettra de corriger la situation. PMID:19721781

Balancing the people, profit and planet dimensions in international marketing channels : a study on coordinating mechanisms in the Nile perch channel from Lake Victoria

NARCIS (Netherlands)

Kambewa, E.

2007-01-01

Keywords: people, profit, planet, marketing channels, contracts, sustainability, quality,LakeVictoria, conjointlang=EN-GB style='mso-ansi-language:NL'>lang=EN-GB style='mso-ansi-language:EN-GB'>analysislang=EN-GB

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.

Science.gov (United States)

Zhang, Miao; D'Aniello, Cristina; Verkerk, Arie O; Wrobel, Eva; Frank, Stefan; Ward-van Oostwaard, Dorien; Piccini, Ilaria; Freund, Christian; Rao, Jyoti; Seebohm, Guiscard; Atsma, Douwe E; Schulze-Bahr, Eric; Mummery, Christine L; Greber, Boris; Bellin, Milena

2014-12-16

Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening cardiac arrhythmias. Patients display delayed cardiac repolarization, associated high risk of sudden death due to ventricular tachycardia, and congenital bilateral deafness. In contrast to the autosomal dominant forms of long QT syndrome, JLNS is a recessive trait, resulting from homozygous (or compound heterozygous) mutations in KCNQ1 or KCNE1. These genes encode the α and β subunits, respectively, of the ion channel conducting the slow component of the delayed rectifier K(+) current, IKs. We used complementary approaches, reprogramming patient cells and genetic engineering, to generate human induced pluripotent stem cell (hiPSC) models of JLNS, covering splice site (c.478-2A>T) and missense (c.1781G>A) mutations, the two major classes of JLNS-causing defects in KCNQ1. Electrophysiological comparison of hiPSC-derived cardiomyocytes (CMs) from homozygous JLNS, heterozygous, and wild-type lines recapitulated the typical and severe features of JLNS, including pronounced action and field potential prolongation and severe reduction or absence of IKs. We show that this phenotype had distinct underlying molecular mechanisms in the two sets of cell lines: the previously unidentified c.478-2A>T mutation was amorphic and gave rise to a strictly recessive phenotype in JLNS-CMs, whereas the missense c.1781G>A lesion caused a gene dosage-dependent channel reduction at the cell membrane. Moreover, adrenergic stimulation caused action potential prolongation specifically in JLNS-CMs. Furthermore, sensitivity to proarrhythmic drugs was strongly enhanced in JLNS-CMs but could be pharmacologically corrected. Our data provide mechanistic insight into distinct classes of JLNS-causing mutations and demonstrate the potential of hiPSC-CMs in drug evaluation.

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

TIMP2 gene polymorphisms are associated with hypertension in patients with myocardial infarction. José Manuel Rodríguez-Pérez Nancy Martínez-Rodríguez Gilberto Vargas-Alarcón Maite Vallejo Irma Eloisa Monroy-Muñoz Carlos Posadas-Romero Eric Kimura-Hayama Teresa Juárez-Cedillo José Manuel Fragoso ...

Nukufilmi erootika / Jaan Ruus

Index Scriptorium Estoniae

Ruus, Jaan, 1938-2017

2005-01-01

Kaks eesti nukufilmi - "Laud" : autorid Jelena Girlin ning Mari-Liis Bassovskaja : operaator ja kaasrežissöör Urmas Jõemees : helilooja Malle Maltis : Nukufilm OÜ 2004 ja "Generatio" : stsenarist, kunstnik ja režissöör Mait Laas : konsultant Paavo Matsin : operaatorid Ragnar Neljandi, Raivo Möllits : helilooja Tiit Kikas : Nukufilm OÜ - Icon Film (Saksamaa) 2005

Animatsiooni vastu ei saa ükski / Mikk Rand

Index Scriptorium Estoniae

Rand, Mikk, 1970-

1998-01-01

21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

Esilinastuvad eesti animafilmid

Index Scriptorium Estoniae

1998-01-01

21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

Kuus uut Eesti filmi korraga ekraanil / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo, 1958-

1998-01-01

21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

Innovations in microspore embryogenesis in Indonesian hot pepper (Capsicum annuum L.) and Brassica napus L.

NARCIS (Netherlands)

Supena, E.D.J.

2004-01-01

Hot pepper (lang=EN-US style='mso-bidi-font-size:12.0pt'>Capsicum annuumlang=EN-US style='mso-bidi-font-size:12.0pt;font-style:normal'>L.) is the most important vegetable inlang=EN-US

An Improved Whole Life Satisfaction Theory of Happiness

Directory of Open Access Journals (Sweden)

Jussi Suikkanen

2011-01-01

Full Text Available

lang="EN-GB">According to the popular Whole Life Satisfaction theories of happiness, an agent is happy when she judges that her life fulfils her ideal life-plan. Fred Feldman has recently argued that such views cannot accommodate the happiness of spontaneous or preoccupied agents who do not consider how well their lives are going. In this paper, I formulate a new Whole Life Satisfaction theory lang="EN-GB">that is not vulnerable to thislang="EN-GB"> objection. My proposal is inspired by Michael Smith’s advice-model of desirability. lang="EN-GB">According to itlang="EN-GB">, an agent is happy when a more informed and rational hypothetical version of her would judge that the agent’s actual life matches the best life-plan for her. I will argue that my new Whole Life Satisfaction theory lang="EN-GB">is lang="EN-GB">a flexible model that canlang="EN-GB"> lang="EN-GB">avoid many

Socio-economic, agronomic and molecular analysis of yam and cowpea diversity in the Guinea-Sudan transition zone of Benin

NARCIS (Netherlands)

Zannou, A.

2006-01-01

Keywords: lang=EN-GB style='font-size:11.0pt;mso-bidi-font-style:italic'>Cowpea (lang=EN-GB style='font-size:11.0pt'>Vigna unguiculatalang=EN-GB style='font-size:11.0pt'>(L.) Walp.),

Description d'un nouveau brûleur compact. Fonctionnement en régime de gaz prémélangés Description of a New Compact Premixed Gas Burner

Directory of Open Access Journals (Sweden)

Minetti R.

2006-11-01

Full Text Available On décrit un nouveau brûleur compact à gaz, de haut rendement et d'une puissance variable de 1 à 5 kW. La source de chaleur est une flamme plate d'un prémélange stoechiométrique de gaz naturel et d'air stabilisé sur une grille d'une surface de 100 cm2. Plusieurs grilles en acier inoxydable sont comparées. Elles diffèrent par leur épaisseur, le nombre et la dimension des trous. Un échangeur de chaleur en laiton à circulation d'eau peut être approché jusqu'à 7 mm de la surface du brûleur. La température des gaz frais, le débit et la position de l'échangeur ont été modifiés et les conditions optimales de fonctionnement sont décrites. Les températures à travers les gaz frais, la flamme, les gaz brûlés et les fumées, ont été mesurées. Un modèle simple des échanges de chaleurs est présenté. Il permet une meilleure compréhension des processus de transfert et facilite le choix des conditions opératoires. Dans les meilleures conditions, 93 % du contenu thermique du mélange gazeux est transféré à l'échangeur. Some general characteristics of a compact and efficient gas burner are described (1-5 kW. The heat source is a premixed flat flame stabilized on a 100 cm2 grid fed by a stoechiometric mixture of air and natural gas. Various types of stainless steel grids have been investigated. They differ according to their thickness and to the number and size of the holes. A circulating water heat exchanger made of brass can be approached to the flame as close as 7 mm above the burner surface. The temperature of the inlet gas mixture, the flow rate, and the position of the heat exchanger have been varied. The best working conditions are given as well as the temperature through the fresh gaseous mixture, the temperature profiles of the flame and the temperature of the fumes. From heat transfer calculations a simple model is presented. It gives better insight into the heat transfer processes and facilitates a judicious

Reproduction et Diversité Génétique chez Parkia biglobosa (Jacq.) G. Don

NARCIS (Netherlands)

Sina, S.

2006-01-01

Parkialang=EN-GB style='font-size:12.0pt'>biglobosalang=EN-GB style='font-size:12.0pt'>(Jacq.)lang=EN-GB style='font-size:12.0pt'>G.Don, African

Contribution of Holstein cows to sustainability of dairy systems in Brazil

NARCIS (Netherlands)

Araujo Waltrick, de B.

2003-01-01

Keywords: sustainability,lang=EN-GB style='font-size:12.0pt; mso-bidi-font-size:10.0pt'>Holsteinlang=EN-GB style='font-size:12.0pt;mso-bidi-font-size:10.0pt'>cows,lang=EN-GB

Molecular studies on protein- and carbohydrate-converting ezymes from thermophilic bacteria

NARCIS (Netherlands)

Kluskens, L.D.

2004-01-01

Microorganisms that are able to grow at highlang=EN-US style='font-size:11.5pt'>tempelang=EN-US style='font-size:11.5pt'>ratures are calledthermophiles(>55lang=EN-US

Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in a mouse model of human Jervell and Lange-Nielsen deafness syndrome.

Science.gov (United States)

Chang, Qing; Wang, Jianjun; Li, Qi; Kim, Yeunjung; Zhou, Binfei; Wang, Yunfeng; Li, Huawei; Lin, Xi

2015-08-01

Mutations in the potassium channel subunit KCNQ1 cause the human severe congenital deafness Jervell and Lange-Nielsen (JLN) syndrome. We applied a gene therapy approach in a mouse model of JLN syndrome (Kcnq1(-/-) mice) to prevent the development of deafness in the adult stage. A modified adeno-associated virus construct carrying a Kcnq1 expression cassette was injected postnatally (P0-P2) into the endolymph, which resulted in Kcnq1 expression in most cochlear marginal cells where native Kcnq1 is exclusively expressed. We also found that extensive ectopic virally mediated Kcnq1 transgene expression did not affect normal cochlear functions. Examination of cochlear morphology showed that the collapse of the Reissner's membrane and degeneration of hair cells (HCs) and cells in the spiral ganglia were corrected in Kcnq1(-/-) mice. Electrophysiological tests showed normal endocochlear potential in treated ears. In addition, auditory brainstem responses showed significant hearing preservation in the injected ears, ranging from 20 dB improvement to complete correction of the deafness phenotype. Our results demonstrate the first successful gene therapy treatment for gene defects specifically affecting the function of the stria vascularis, which is a major site affected by genetic mutations in inherited hearing loss. © 2015 The Authors. Published under the terms of the CC BY 4.0 license.

Short outlines of books by Estonian authors : [annotations] / Rutt Hinrikus, Janika Kronberg

Index Scriptorium Estoniae

Hinrikus, Rutt, 1946-

1999-01-01

Ehin, Andres. Seljatas sada meest; Ilmet, Peep. Tuuldunud luule; Kaplinski, Jaan. Öölinnud. Öömõtted; Kender, Kaur. Iseseisvuspäev; Kesküla, Kalev. Vabariigi laulud; Luik, Viivi. Maa taevas; Nõu, Helga. Hundi silmas; Raun, Mait. Wake up; Remsu, Olev. Haapsalu tragöödia; Sauter, Peeter. Kogu moos; Undusk, Jaan. Maagiline müstiline keel; Vint, Toomas. Kunstnikuromaan

Kodumaine multifilm õilmitseb / Mart Rummo

Index Scriptorium Estoniae

Rummo, Mart

2001-01-01

Tähistamaks eesti animafilmi 70. aastapäeva näidatakse täna Kinomajas kuut uut multifilmi : 13-osaline lamenukkfilm "Tulelaeva kulid" (režissöör Mait Laas), Ülo Pikkovi kaks joonisfilmi "Superlove" ja "Peata ratsanik", Priit Tenderi joonisfilm "Mont Blanc", Kaspar Jancise joonisfilm "Romanss" ja Janno Põldma - Heiki Ernitsa laste joonisfilmiseriaali "Lepatriinude jõulud" 5-min. trailer

Vabaduse väljak = The first design stage of Freedom Square / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinna Vabaduse väljakust, mis pälvis Eesti Kultuurkapitali 2009. aasta aastapreemia uue kvaliteedi eest Eesti linnaehituses ja avaliku ruumi loomisel. Arhitektid: Andres Alver, Veljo Kaasik, Tiit Trummal, kaasautorid Indrek Rünkla, Tarmo Laht, Sven Koppel, Ulla Saar, Toomas Tammis (Alver Arhitektid OÜ). Ajaloolane Rein Zobel. Žürii liikmete Kalle Komissarovi ja Mait Summataveti hinnang väljakule

Tjoplõi dozhd v zale suda / Boris Tuch

Index Scriptorium Estoniae

Tuch, Boris, 1946-

2006-01-01

Mängufilm "Meeletu" : stsenaristid Jaan Tätte, Elmo Nüganen : režissöör Elmo Nüganen : operaator Mait Mäekivi : produtsent Kristian Taska : helilooja Jaak Jürisson : peaosas Rain Simmul : Taska Film - Eesti Televisioon 2006. Võrreldakse näidendi lavastust ja filmi. Arvustuses on Jüri osatäitjaks ekslikult nimetatud lavastuse osatäitjat Allan Noormetsa ( tegelikult Aivar Tommingas)

Suur esilinastamine

Index Scriptorium Estoniae

1998-01-01

21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer. Aut. : M.R

Arvustused / Aleks Lange

Index Scriptorium Estoniae

Lange, Aleks

2000-01-01

Uute heliplaatide Nils Petter Molvaer "Solid Ether", Leona Naess "Comatised", Naivity in Black II "A Tribute to Black Sabbath", Papa Roach "Infest", A Perfect Circle "Mer de Noms", Queens of the Stone Age "Rated R", "Road Trip" (soundtrack) tutvustused

Plaadid / Aleks Lange

Index Scriptorium Estoniae

Lange, Aleks

2003-01-01

Uutest plaatidest Ricky Martin "Almas del Silencio", Paul McCartney "Back In Th e World", The Ultimate "Diva Collection", Girls Aloud "Sound Of The Underground", Blacky "Kui me päikeseloojangut ootama peaks", Christoph Poppen, Münchner Kammerorchester, The Hilliard Ensemble, Cerys Matthews "Cockahoop", Radiohead "Hail to the Thief"

De lange weg

NARCIS (Netherlands)

Maas Geesteranus, R.A.

1968-01-01

Peziza alpina (Fuck.) Cooke (1876) and Peziza alpina (Fuck.) Oud. (1885) are recombinations based on Humaria alpina Fuck. (1874), and have no relation with Peziza alpina Sauter (1878). While the identity of Fuckel’s species is left out of consideration (as it will be discussed in a future paper),

Langs Rembrandts roem

NARCIS (Netherlands)

Belien, Herman; Knevel, Paul

2006-01-01

The Dutch love Rembrandt. This year will see a celebration of the 400th anniversary of his birth, remembered with many festivities and much discussed, with many high profile exhibitions. Yet this homage is less obvious than many might think. Rembrandt only became famous after his death, thanks to

Smagsdommernes lange skygge

DEFF Research Database (Denmark)

Hermansen, Judy

2009-01-01

Den franske sociolog Pierre Bourdieu påstod, at smag er noget man tilegner sig gennem opdragelse og socialisering og derfor så dybt rodfæstet i personligheden, at den er meget vanskelig at ændre på. Denne opfattelse har været kritiseret af mange postmoderne trendforskere og symbolanalytikere, som...

Processes Governing Alkaline Groundwater Chemistry within a Fractured Rock (Ophiolitic Mélange Aquifer Underlying a Seasonally Inhabited Headwater Area in the Aladağlar Range (Adana, Turkey

Directory of Open Access Journals (Sweden)

Cüneyt Güler

2017-01-01

Full Text Available The aim of this study was to investigate natural and anthropogenic processes governing the chemical composition of alkaline groundwater within a fractured rock (ophiolitic mélange aquifer underlying a seasonally inhabited headwater area in the Aladağlar Range (Adana, Turkey. In this aquifer, spatiotemporal patterns of groundwater flow and chemistry were investigated during dry (October 2011 and wet (May 2012 seasons utilizing 25 shallow hand-dug wells. In addition, representative samples of snow, rock, and soil were collected and analyzed to constrain the PHREEQC inverse geochemical models used for simulating water-rock interaction (WRI processes. Hydrochemistry of the aquifer shows a strong interseasonal variability where Mg–HCO3 and Mg–Ca–HCO3 water types are prevalent, reflecting the influence of ophiolitic and carbonate rocks on local groundwater chemistry. R-mode factor analysis of hydrochemical data hints at geochemical processes taking place in the groundwater system, that is, WRI involving Ca- and Si-bearing phases; WRI involving amorphous oxyhydroxides and clay minerals; WRI involving Mg-bearing phases; and atmospheric/anthropogenic inputs. Results from the PHREEQC modeling suggested that hydrogeochemical evolution is governed by weathering of primary minerals (calcite, chrysotile, forsterite, and chromite, precipitation of secondary minerals (dolomite, quartz, clinochlore, and Fe/Cr oxides, atmospheric/anthropogenic inputs (halite, and seasonal dilution from recharge.

Structure, expression profile and phylogenetic inference of chalcone isomerase-like genes from the narrow-leafed lupin (Lupinus angustifolius L. genome

Directory of Open Access Journals (Sweden)

Łucja ePrzysiecka

2015-04-01

Full Text Available Lupins, like other legumes, have a unique biosynthesis scheme of 5-deoxy-type flavonoids and isoflavonoids. A key enzyme in this pathway is chalcone isomerase (CHI, a member of CHI-fold protein family, encompassing subfamilies of CHI1, CHI2, CHI-like (CHIL, and fatty acid-binding (FAP proteins. Here, two Lupinus angustifolius (narrow-leafed lupin CHILs, LangCHIL1 and LangCHIL2, were identified and characterized using DNA fingerprinting, cytogenetic and linkage mapping, sequencing and expression profiling. Clones carrying CHIL sequences were assembled into two contigs. Full gene sequences were obtained from these contigs, and mapped in two L. angustifolius linkage groups by gene-specific markers. Bacterial artificial chromosome fluorescence in situ hybridization approach confirmed the localization of two LangCHIL genes in distinct chromosomes. The expression profiles of both LangCHIL isoforms were very similar. The highest level of transcription was in the roots of the third week of plant growth; thereafter, expression declined. The expression of both LangCHIL genes in leaves and stems was similar and low. Comparative mapping to reference legume genome sequences revealed strong syntenic links; however, LangCHIL2 contig had a much more conserved structure than LangCHIL1. LangCHIL2 is assumed to be an ancestor gene, whereas LangCHIL1 probably appeared as a result of duplication. As both copies are transcriptionally active, questions arise concerning their hypothetical functional divergence. Screening of the narrow-leafed lupin genome and transcriptome with CHI-fold protein sequences, followed by Bayesian inference of phylogeny and cross-genera synteny survey, identified representatives of all but one (CHI1 main subfamilies. They are as follows: two copies of CHI2, FAPa2 and CHIL, and single copies of FAPb and FAPa1. Duplicated genes are remnants of whole genome duplication which is assumed to have occurred after the divergence of Lupinus, Arachis

Screening of Long Q-T Syndrome in Patients with Congenital Sensorineural Hearing Loss (Jervell and Lange Neilesen Syndrome: Prevention of Fatal Events

Directory of Open Access Journals (Sweden)

Farid Matin

2001-01-01

Full Text Available Objective:The idiopathic long Q-T syndrome is an infrequently occurring disorder in which affected individuals have an unusual electrocardiographic repolarization abnormality presenting as syncope or loss of consciousness related to ventricular tachycardia or fibrillation. Congenital long Q-T prolongation can be associated with congenital deafness in an autosomal recessive manner (Jervell and Lange-Nielsen syndrome. The purpose of this stuff was to screen this electrocardiographic abnormality in deaf-mute school children in our population, which has not been yet performed. Materials & Methods:  Of 1190 patients with hearing loss, 779 had congenital sensorineural deafness (CSD, aged 13±3.8 years (4-24, 63% female and 37% male. The family history of deafness was as follows: Cardiac axis deviation was found in 56 (7% patients. Electrical conduction abnormalities were found in 12 (15% patients, Wolff-Parkinson-White syndrome, sinus bradycardia, and sinus arrhythmia were found in 2 (0.25%, 4 (0.5%, and 3 (0.38% patients, respectively. The Q-T interval, and Q-Tc duration were 312.6±28.9 ms (200-500 ms, median 320 ms, and 383.6±29.3 ms (232-527 ms, median 413ms, respectively. Long Q-T syndrome was found in 4 (0.5% patients (3F and 1M. Results: Two of these 4 patients had total deafness and 2 had profound hearing loss. None of the patients with mild deafness had Q-T prolongation. Only one of these patients was symptomatic, and had been treated as a case of epilepsy for several years. Conclusion: This data supports the presence of long Q-T syndrome in patients with sensorineural hearing loss in our population, so routine electrocardiographic screening of anyone with congenital deafness is warranted to prevent subsequent associated cardiac arrhythmias and sudden cardiac death.

Blueschist metamorphism and its tectonic implication of Late Paleozoic-Early Mesozoic metabasites in the mélange zones, central Inner Mongolia, China

Science.gov (United States)

Zhang, Jinrui; Wei, Chunjing; Chu, Hang

2015-01-01

Blueschists in central Inner Mongolia are distributed as layers and blocks in mélanges including the southern zone in Ondor Sum area and the northern zone in Manghete and Naomuhunni areas. They have been attributed to the subduction of Early Paleozoic oceanic crust. Blueschists from Ondor Sum and Naomuhunni are characterized by occurrence of sodic amphibole coexisting with epidote, albite, chlorite, calcic amphibole (in Ondor Sum) and muscovite (in Naomuhunni). Blueschists in Manghete contain porphyroblastic albite with inclusions of garnet and epidote in a matrix dominated by calcic-sodic amphibole, epidote, chlorite, albite and muscovite. Phase equilibria modeling for three blueschist samples using pseudosection suggest that the AlM2 contents in sodic amphibole can be used as a good barometer in the limited assemblage involving sodic amphibole + actinolite + epidote + chlorite + albite + quartz under pressures 7-10 kbar. In the sodic amphibole-bearing assemblages, the NaM4 contents in sodic amphibole mainly decrease as temperature rises, being a potential thermometry. The calculated pseudosections constrain the P-T conditions of blueschists to be 3.2-4.2 kbar/355-415 °C in Ondor Sum, 8.2-9.0 kbar/455 °C-495 °C in Manghete and 6.6-8.1 kbar/420-470 °C in Naomuhunni. These P-T estimates indicate a rather high geothermal gradient of 18-25 °C/km for the blueschist metamorphism, being of intermediate P/T facies series. Available zircon U-Pb age data suggests that the protoliths of blueschists were formed later than Late Paleozoic-Early Mesozoic and metamorphosed soon afterwards. An alternative interpretation for the tectonic implication of blueschists in central Inner Mongolia is that they may be a new type attributed to closure of limited ocean basins and do not represent a tectonic regime occurred in conventional subduction setting.

XML Namespace與RDF的基本概念 | The Basic Concepts of XML Namespace and RDF

Directory of Open Access Journals (Sweden)

陳嵩榮 Sung-Jung Chen

1999-04-01

Full Text Available

頁次：88-100

XML Namespaces機制允許在lang="EN-US">XML文件中以一個lang="EN-US">URI 來限定元素名稱或屬性名稱，提供一種在lang="EN-US">Web上具有唯一性的命名方式，以解決不同的lang="EN-US">XML文件元素名稱與屬性名稱可能衝突的問題；lang="EN-US">RDF 主要是為lang="EN-US">Metadata在lang="EN-US">Web 上的各種應用提供一個基礎結構，使應用程式之間能夠在lang="EN-US">Web上交換lang="EN-US">Metadata，以促進網路資源的自動化處理。本文透過一連串的實例來介紹lang="EN-US">XML Namespace與lang="EN-US">RDF的資料模型及語法。

lang="EN-US">XML namespaces provide a simple method for qualifying element and attribute names used in XML documents by associating them with namespaces identified by URI references. RDF is a foundation for processing metadata. It provides interoperability between

FUNGI INCIDENCE ON Jatropha curcas L. SEEDS INCIDÊNCIA DE FUNGOS EM SEMENTES DE PINHÃO-MANSO

Directory of Open Access Journals (Sweden)

Charline Zaratin Alves

2011-07-01

Full Text Available

lang="pt-BR">lang="pt-BR">The knowledge on seed pathogens is essential for setting management recommendations. Thus, aiming to determine the pathogens associated with lang="pt-BR">Jatropha curcaslang="pt-BR"> L., in order to develop strategies to control them, the blotter test, modified with hydric restrictor NaCl - 1.0 MPa, and evaluation after seven days of incubation, at 25°C, with a 12-hours photoperiod, was used. The lang="pt-BR">Jatrophalang="pt-BR"> seeds evaluated presented a high level of fungal species, regardless of their surface disinfection. Nineteen different fungi genera were identified, especially lang="pt-BR">Alternaria alternata

Plaadid / Mait Eelrand, Toomas Puna, Veiko Pesur...[jt.

Index Scriptorium Estoniae

2007-01-01

Uutest heliplaatidest Wolf & Cub "Vessels", Karl MAdis & Karavan "Taevalik meloodia ئ Nat King Cole'i laule", Sophie Ellis-Bextor "Trip The Light Fantastic", Him "Uneasy Listening 1&2", Kognito "Muutuv"

Katse portreteerida nõukogude kosmosemaja / Mait Väljas

Index Scriptorium Estoniae

Väljas, Mait

2011-01-01

Prantsuse fotograafist Frédéric Chaubinist, kes pildistas NSV Liidus 1975.-1990. a. ehitatud eripäraseid hooneid, korraldas fotonäitusi. F. Chaubini raamatust "СССР : cosmic communist constructions photographed" (Köln : Taschen, 2011), raamatusse jõudnud eesti arhitektuurist

Rotermanni soolalao urbanistliku pargi ideekonkurss / Mait Väljas

Index Scriptorium Estoniae

Väljas, Mait

2009-01-01

Eesti Arhitektuurimuuseumi korraldatud avalikust konkursist, Ignar Fjuki koostatud võistlustingimustest, premeeritud töödest. 1. preemia sai töö "Piazza", autor Villem Tomiste, (AB Kosmos)), 2. preemia töö "Muesuum", autor Ott Kadarik, (AB Kosmos), 3. preemia töö "Arhitektuuri allee", autor Jürgen Lepper, (AB Dimensioon). Anti välja üks ergutuspreemia, ära märgiti kaks tööd

Teadusmõtte ja teaduse mineviku lood / Mait Talts

Index Scriptorium Estoniae

Talts, Mait, 1964-

2011-01-01

Arvustus: Baltic Journal of European Studies. Selected papers of the 24th International Baltic Conference on the history of science and the follow-up seminar (2011, nr. 1). Tallinn : Tallinn University of Technology, 2011

Experiment list: SRX189420 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ription=lymphoblastoid cell line, De Lange phenotype; developmental delay; profound retardation; seizures; 3 cousins...ymphoblastoid cell line, De Lange phenotype; developmental delay; profound retardation; seizures; 3 cousin

Karl Menningu (ja iseenese) päästmiseks / Ants Hein

Index Scriptorium Estoniae

Hein, Ants, 1952-

2008-01-01

Vastuseks Karin Hallas-Murula arvustusele "Maja, mis on sümbol" (Sirp, 2007, 5. X, lk. 13) ja Mait Väljase arvustusele "Iseolemise algus arhitektuuris" (Maja, 2008, nr. 1, lk. 86-87) oma 2007. a. ilmunud raamatust "Maja kui sümbol : Eesti Üliõpilaste Seltsi hoone Tartus" kohta. Georg Hellati ja Karl Menningu osalusest EÜS-i hoone sünniloos. Frank Lloyd Wrightist kui võimalikust eeskujuandjast

Stepping Up: Burden Sharing by NATO’s Newest Members

Science.gov (United States)

2014-11-01

trustworthiness as a partner in Bosnia and Herzegovina, Kosovo, Af- ghanistan, and also in Iraq. Now, as a full member of the Alliance, our responsibility in...Rein Lang at the celebrating of the first anniversary of Estonia’s NATO accession,” Tallinn, Estonia, April 4, 2005, available from www.vm.ee/eng...Lang, Rein (Estonian Foreign Minister). “Address by Foreign Minister Rein Lang at the celebration of the first anniversary of Estonia’s NATO accession

97 miljonit aastaga maha mängitud / Kaisa Tahlfeld

Index Scriptorium Estoniae

Tahlfeld, Kaisa

2008-01-01

Olympic EG kolmanda kvartali kasum langes 94%, 7,4 miljonile kroonile. Vt. samas: Kokkuhoiukava raskuskese langes kolmandasse kvartalisse. Diagramm: Käive ja kasum. Kommenteerib LHV analüütik Sten Pisang

Personalised Health Care, the need for reassessment. A HTA perspective far beyond cost-effectiveness

Directory of Open Access Journals (Sweden)

Iñaki Gutiérrez-Ibarluzea

2012-11-01

Full Text Available

lang="en-GB">Background:lang="en-GB"> personalised health care has been claimed to play an outstanding role in the future health services. In fact, health care systems will have to face changes in their work flows and processes due to the implementation of personalised technologies. Health Technology Assessment provides information to decision makers at any level on the introduction and exclusion of health technologies from the health care systems.

lang="en-GB">Methods: lang="en-GB">the definition of Health Technology Assessment (HTA and the concepts and questions raised in the EUnetHTA core model, were used as a framework to analyse the impact of these new services in health care provision.

lang="en-GB">Results: lang="en-GB">personalised health care services and products are health technologies, mainly diagnostics that have a broad impact in the health care systems. Although, safety, clinical effectiveness and economical aspects and consequences have been described, ethical, social and organisational issues raised questions that should be answered before considering their implementation in the health systems. Special attention should be paid on new requirements for regulation, data protection and the empowerment of citizen and health professionals.

lang="en-GB">Conclusions:lang="en-GB"> the benefits and harms of personalised health-care technologies should be decided on a “case by case” rather than a “one size fits all” basis and has to be analysed under its many aspects. The combination of genetic, clinical and environmental factors is crucial for the correct understanding of personalised medicine and

Altijd wat te doen bij het sluisje van Dorkwerd

NARCIS (Netherlands)

den Hollander, Franciscus; van Dam, Vanessa; Langenberg, Sjaak

2006-01-01

Ooggetuigeverslagen van 84 Nederlandse auteurs die op 1 september 2006 van 11.00 tot 17.00 uur langs de 118 kilometer lange vaarroute van Lemmer naar Delfzijl (Prinses Margrietkanaal, Van Starkenborg-kanaal, Eemskanaal) zaten.

Lapsesuu või PR-guru? / Airi Ilisson

Index Scriptorium Estoniae

Ilisson, Airi, 1980-

2007-01-01

Justiitsminister Rein Lang on autori hinnangul tuntud oma ootamatute arvamustega. CV. Vt. samas: Skandaal: Kuidas Lang politseid ja allilma seostades tormi tekitas. Kommenteerivad: Hans H. Luik, Hannes Astok, Laine Jänes, Rein Kilk ja Ulvi Kuusk

La persona feliz : personalidad, bienestar psicológico subjetivo y variables predictoras

OpenAIRE

Martín Martín, Carla

2015-01-01

El propósito de este trabajo es realizar una réplica del estudio de Maite Garaigordobil, Jone Aliri e Iraide Fontaneda, titulado “Bienestar Psicológico Subjetivo: diferencias de sexo, relaciones con dimensiones de personalidad y variables predictoras”(2009). En dicho trabajo, analizan diferentes variables en relación al bienestar psicológico subjetivo, exploran las relaciones del bienestar psicológico y el material con las dime...

Mustamäe Maarja Magdaleena kiriku arhitektuurivõistlus = Architecture competition for Mustamäe`s Church of Mary Magdalene / Pille Epner

Index Scriptorium Estoniae

Epner, Pille

2013-01-01

Arhitektuurikonkursist, võidutööst "Fiat Lux" (arhitektid Risto Parve, Kai Süda, Martin Kinks, Margit Valma, arhitektuuriteadlane Mait Väljas, Karisma Arhitektid), 2. koha pälvinud tööst "Õhuke Koht" (Pille Noole, Üllar Ambos, Kaisa Lasner, Kerttu Karjust, Jiannis Lykouras, Arhitektuurinurk), 3. koha pälvinud tööst "Tee" (Villem Tomiste, Stuudio Tallinn). Loetletud ostupreemia ja kolm tunnustuse pälvinud võistlustööd

Barbarid, plastiliinijänes, Miriam ja Frank Muller / Annika Koppel

Index Scriptorium Estoniae

Koppel, Annika

2003-01-01

Nukufilm näitab 4 uut filmi : "Barbarid" (stsenaristid Andrus Kivirähk ja Hardi Volmer, režissöör H. Volmer), "Porgand" (stsenarist Peep Pedmanson, režissöör Pärtel Tall), "Miriami jõulupäkapikk" (stsenaristid Leelo Tungal ja Peep Pedmanson, režissöör Mait Laas), "Kuuvaatleja" (reklaamitreiler Frank Mulleri kellafirmale ; stsenarist, režissöör, kunstnik Mati Kütt)

Weed competitiveness and yielding ability of aerobic rice genotypes

NARCIS (Netherlands)

Zhao, D.L.

2006-01-01

Keywords:lang=EN-GB>    Broad-sense heritability; Crop vigour; Genetic correlation; Indirect selection index; Plant erectness; Rice germplasm; Seeding rate; Vegetative growth; Weed-suppressive ability.

lang=EN-GB

Molecular identification and characterization of Colletotrichum sp. isolates from Tahiti lime, tamarillo, and mango

Directory of Open Access Journals (Sweden)

Sanabria Adriana

2010-11-01

Full Text Available

lang="EN-US">Anthracnose is a very limiting disease affecting production, as well as postharvest quality of numerous fruit crops in Colombia. The current management practices for this disease are partially effective due to limited information about the etiology, the inoculum sources, population structure and variation of the pathogen. A total of 293 lang="EN-US">Colletotrichum lang="EN-US">isolates were obtained from symptomatic tissues collected from Tahiti lime, tamarillo and mango orchards. To determine the lang="EN-US">Colletotrichum lang="EN-US">species causing the symptoms, amplification, and PCR product analysis for intergenic regions of the ribosomal DNA were conducted. Genetic diversity of the fungal population was assessed with Random Amplified Microsatellites (RAMS. Results of this study indicated that anthracnose in Tahiti lime and tamarillo are caused by lang="EN-US">Colletotrichun acutatum lang="EN-US">whereas symptoms on

PHYSICAL CHARACTERISTICS AND GERMINATION OF Dyckia goehringii Gross & Rauh (BROMELIACEAE SEEDS UNDER DIFFERENT TEMPERATURES CARACTERÍSTICAS FÍSICAS E GERMINAÇÃO DE SEMENTES DE Dyckia goehringii Gross & Rauh (BROMELIACEAE SOB DIFERENTES TEMPERATURAS

Directory of Open Access Journals (Sweden)

Natan Fontoura da Silva

2010-10-01

Full Text Available

lang="pt-BR" align="JUSTIFY">lang="en-GB">Dyckia goehringiilang="en-GB"> is a bromeliad native from lang="en-GB">Cerradolang="en-GB"> (Brazilian savannah. Despite its high ornamental value, because of the silvery appearance of its leaves, it is not yet commercialized due to lack of information on its conservation and agronomic employment. The present investigation aimed to appraise the physical and physiological performance of seeds, during the imbibition andlang="en-GB"> lang="en-GB">germination period, under several temperatures, as well as to establish temperature parameters for germination tests. The moisture content and the fresh and dry mass content of one hundred seeds were determined. The imbibition capacity, germination and vigour of seeds and seedlings of large and small seeds were observed under temperatures of 20°C, 25°C, 30°C, and 35°C. The results showed that there are no obstructions to water absorption and that this feature is influenced by seeds size. The best vigour and germination rate were observed to large seeds, which produce more vigorous seedlings than small seeds, mainly at 30°C, and germination tests should be carried out on the 7th and 14th days after sowing.

lang="pt-BR" align="JUSTIFY">lang="en-GB">KEY-WORDS: Dlang="en-GB">yckia goehringiilang="en-GB">;lang="en-GB"> lang="en-GB">seed vigour and size; imbibition.

mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome

Directory of Open Access Journals (Sweden)

Beatriz Puisac

2017-02-01

Full Text Available Cornelia de Lange syndrome (CdLS is a congenital developmental disorder characterized by craniofacial dysmorphia, growth retardation, limb malformations, and intellectual disability. Approximately 60% of patients with CdLS carry a recognizable pathological variant in the NIPBL gene, of which two isoforms, A and B, have been identified, and which only differ in the C-terminal segment. In this work, we describe the distribution pattern of the isoforms A and B mRNAs in tissues of adult and fetal origin, by qPCR (quantitative polymerase chain reaction. Our results show a higher gene expression of the isoform A, even though both seem to have the same tissue distribution. Interestingly, the expression in fetal tissues is higher than that of adults, especially in brain and skeletal muscle. Curiously, the study of fibroblasts of two siblings with a mild CdLS phenotype and a pathological variant specific of the isoform A of NIPBL (c.8387A > G; P.Tyr2796Cys, showed a similar reduction in both isoforms, and a normal sensitivity to DNA damage. Overall, these results suggest that the position of the pathological variant at the 3´ end of the NIPBL gene affecting only isoform A, is likely to be the cause of the atypical mild phenotype of the two brothers.

Affected sib pair tests in inbred populations.

Science.gov (United States)

Liu, W; Weir, B S

2004-11-01

The affected-sib-pair (ASP) method for detecting linkage between a disease locus and marker loci was first established 50 years ago, and since then numerous modifications have been made. We modify two identity-by-state (IBS) test statistics of Lange (Lange, 1986a, 1986b) to allow for inbreeding in the population. We evaluate the power and false positive rates of the modified tests under three disease models, using simulated data. Before estimating false positive rates, we demonstrate that IBS tests are tests of both linkage and linkage disequilibrium between marker and disease loci. Therefore, the null hypothesis of IBS tests should be no linkage and no LD. When the population inbreeding coefficient is large, the false positive rates of Lange's tests become much larger than the nominal value, while those of our modified tests remain close to the nominal value. To estimate power with a controlled false positive rate, we choose the cutoff values based on simulated datasets under the null hypothesis, so that both Lange's tests and the modified tests generate same false positive rate. The powers of Lange's z-test and our modified z-test are very close and do not change much with increasing inbreeding. The power of the modified chi-square test also stays stable when the inbreeding coefficient increases. However, the power of Lange's chi-square test increases with increasing inbreeding, and is larger than that of our modified chi-square test for large inbreeding coefficients. The power is high under a recessive disease model for both Lange's tests and the modified tests, though the power is low for additive and dominant disease models. Allowing for inbreeding is therefore appropriate, at least for diseases known to be recessive.

Bagatellid : Maailm / Nele-Eva Steinfeld

Index Scriptorium Estoniae

Steinfeld, Nele-Eva

2010-01-01

Muusikasõnumeid maailmast: Grammy auhindadest klassikalise muusika valdkonnas. Sony plaadifirmal kaks uut artisti - pianistid Lang Lang ja Simone Dinnerstein. Skandaal Salzburgi Lihavõttefestivali ümber. Yundi salvestab Chopini sooloteosed. Tenor Rolando Villazon sai hääle tagasi

Optimising the management of complex dynamic ecosystems. An ecological-economic modelling approach

NARCIS (Netherlands)

Hein, L.G.

2005-01-01

Keywords: ecological-economic modelling; ecosystem services; resource use; efficient; sustainability; wetlands, rangelands.lang=EN-GB style='mso-ansi-language: EN-GB'>

lang=EN-GB

Production of Methanol-Higher Alcohol Mixtures from Natural Gas via Syngas Chemistry Production de mélanges méthanol-alcools supérieurs à partir du gaz, via (CO + H2

Directory of Open Access Journals (Sweden)

Courty P.

2006-11-01

éactions, la déshydratation chimique des alcools par shift-conversionet la formation de produits lourds par croissance de chaîne. Ce dernier point conduit à limiter à 35-45 % en masse, la proportion d'alcools C2+ dans le mélange ciblé (fig. 1. Parmi les différents développements précités, IFP et Idemitsu Kosan ont sélectionné des catalyseurs oxydes mixtes à base de cuivre-cobalt ou cuivre-nickel, lesquels conduisent à des performances intéressantes et, notamment, à des alcools en mélange particulièrement purs. Enfin, l'analyse d'ensemble des données IFP et de la littérature ouverte démontre la fatalité de la coproduction parallèle d'hydrocarbures légers. Les principaux résultats sont les suivants : les catalyseurs cuivre-cobalt, fondés sur des systèmes oxydes mixtes alcalinisés, complexes, subissent de profondes transformations par réduction, puis interaction avec le milieu réactionnel. Leur sélectivité en alcools (fig. 3 varie en raison inverse de la proportion d'alcools C2+ produits. Le procédé de synthèse d'alcools (fig. 4 est fondé sur une technologie adiabatique, pour la section réactionnelle. Le fractionnement est mené par distillation azéotropique. L'intégration dans une chaîne gaz est présentée fig. 5; un rendement énergétique de 56-60% peut ainsi être obtenu. Deux démonstrations du procédé (fig. 6 ont été menées à bien et les mélanges d'alcools obtenus (tableau 5 ont fait l'objet d'essais sur flotte. Des performances typiques sont mentionnées tableau 6. Dans la chaîne gaz-alcools, la production de syngas représente 50% de l'investissement, mais la sélectivite en alcools constitue, en fait, le paramètre déterminant dans l'économie du procédé (tableau 8. L'étude du marché et des données économiques montre, enfin, que l'usage carburant constitue l'essentiel des possibilités de commercialisation. En zone industrialisée (fig. 7 ou en zone éloignée, peu industrialisée (fig. 8, soit le coût op

Obama skal ikke nyde noget af Syrien

DEFF Research Database (Denmark)

Ulrich, Philip Christian

2013-01-01

Mange har i lang tid undret sig over at konflikten i Syrien har kunnet få lov at stå på i så lang tid, uden at USA har vist lederskab og grebet ind. Det er jo den rolle vi er vant til at se USA i. Men Obama skal ikke nyde noget af at engagere sig i Syrien. Det har USA ikke råd til......Mange har i lang tid undret sig over at konflikten i Syrien har kunnet få lov at stå på i så lang tid, uden at USA har vist lederskab og grebet ind. Det er jo den rolle vi er vant til at se USA i. Men Obama skal ikke nyde noget af at engagere sig i Syrien. Det har USA ikke råd til...

Patterns of HIV prevalence among injecting drug users in the cross-border area of Lang Son Province, Vietnam, and Ning Ming County, Guangxi Province, China

Directory of Open Access Journals (Sweden)

Hoang Tran V

2005-08-01

Full Text Available Abstract Background To assess patterns of injecting drug use and HIV prevalence among injecting drug users (IDUs in an international border area along a major heroin trans-shipment route. Methods Cross-sectional surveys of IDUs in 5 sites in Lang Son Province, Vietnam (n = 348 and 3 sites in Ning Ming County, Guangxi Province, China (n = 308. Respondents were recruited through peer referral ("snowball" methods in both countries, and also from officially recorded lists of IDUs in Vietnam. A risk behavior questionnaire was administered and HIV counseling and testing conducted. Results Participants in both countries were largely male, in their 20s, and unmarried. A majority of subjects in both countries were members of ethnic minority groups. There were strong geographic gradients for length of drug injecting and for HIV seroprevalence. Both mean years injecting and HIV seroprevalence declined from the Vietnamese site farthest from the border to the Chinese site farthest from the border. 10.6% of participants in China and 24.5% of participants in Vietnam reported crossing the international border in the 6 months prior to interview. Crossing the border by IDUs was associated with (1 distance from the border, (2 being a member of an ethnic minority group, and (3 being HIV seropositive among Chinese participants. Conclusion Reducing the international spread of HIV among IDUs will require programs at the global, regional, national, and "local cross border" levels. At the local cross border level, the programs should be coordinated on both sides of the border and on a sufficient scale that IDUs will be able to readily obtain clean injection equipment on the other side of the border as well as in their country of residence.

The Jervell and Lange-Nielsen syndrome; atrial pacing combined with ß-blocker therapy, a favorable approach in young high-risk patients with long QT syndrome?

Science.gov (United States)

Früh, Andreas; Siem, Geir; Holmström, Henrik; Døhlen, Gaute; Haugaa, Kristina H

2016-11-01

Patients with Jervell and Lange-Nielsen syndrome (JLNS) exhibit severe phenotypes that are characterized by congenital deafness, very long QT intervals, and high risk of life-threatening arrhythmias. Current treatment strategies include high doses of beta-blocker medication, left cardiac sympathetic denervation, and ICD placement, which is challenging in young children. The purpose of this study was to evaluate the safety and effect of pacing in addition to beta-blocker treatment in children with JLNS. All genetically confirmed patients with JLNS born since 1999 in Norway were included in the study. Data on history of long QT syndrome-related symptoms, QT interval, and beta-blocker and pacemaker treatment were recorded. A total of 9 patients with QT intervals ranging from 510 to 660 ms were identified. Eight patients developed long QT syndrome-related symptoms, and 1 patient died before diagnosis. The survivors received beta-blocker medication. Seven patients also received a pacemaker; 1 had a ventricular lead and 6 had atrial leads. The patient with the ventricular lead died during follow-up. The 6 patients with atrial leads survived without events at a mean follow-up of 6.9 years after pacemaker implantation. Two patients received prophylactic upgrade to a 2-chamber ICD. No arrhythmic events occurred in 6 very young JLNS patients who received atrial pacing in combination with increased doses of beta-blockers during 7-year follow-up. If confirmed in additional patients, this treatment strategy may prevent life-threatening arrhythmias in this high-risk patient group and may act as a bridge to insertion of a 2-chamber ICD when left cardiac sympathetic denervation is not available. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Aggregate morphology and network properties of ovalbumin

NARCIS (Netherlands)

Weijers, M.

2005-01-01

keywords:lang=EN-GB>ovalbumin, hen egg white proteins,lang=EN-GB style='font-family:Symbol;mso-ascii-font-family:"Times New Roman";mso-hansi-font-family: "Times New Roman";mso-char-type:symbol;mso-symbol-font-family:Symbol'>

Integrating science with farmer knowledge: Sorghum diversity management in north-east Ghana

NARCIS (Netherlands)

Kudadjie, C.Y.

2006-01-01

Keywordslang=EN-CA>:   Clang=EN-US style='mso-ansi-language: EN-US'>onvergence of sciences, diversity management, experimentation, farmer knowledge, genetic diversity, Ghana, plant variation, private sector, research, Sorghum

Hitler og Stalin arm i arm

DEFF Research Database (Denmark)

Bryld, Claus

2015-01-01

Levende fortalt bog om pagten mellem Hitler og Stalin, som udløste krigen og kastede lange skygger over Europas historie.......Levende fortalt bog om pagten mellem Hitler og Stalin, som udløste krigen og kastede lange skygger over Europas historie....

Assessing irrigation performance by using remote sensing

NARCIS (Netherlands)

Bandara, K.M.P.S.

2006-01-01

Keywordslang=EN-US>: Performance indicators, performance assessment, diagnostic approach, SEBAL, target level, grain yield, water productivity, error estimation, spatio-temporal resolution.

lang=EN-US>In

Modernistlik ruumikontseptsioon ja nõukogude ideoloogia kohtuvad Viru hotellis / Karen Jagodin

Index Scriptorium Estoniae

Jagodin, Karen, 1982-

2006-01-01

Ajavahemikul 1964-1968 arhitektide Henno Sepmanni ja Mart Pordi poolt projekteeritud ning 1972. a. valminud Viru hotellist Tallinnas, põhjalikum ülevaade hoone interjöörist. Sisearhitektid Väino Tamm, Vello Asi, Taevo Gans, Mait Summatavet ja Loomet Raudsepp. II korruse naiste juuksuri ruumid kujundas Kirsti Laanemaa. II korruse banketisaalis oli Mari Adamsoni gobelään "Tare", suures restoranisaalis Aet Andresma-Tamme ja Mare Soovik-Lobjakase klaaskompositsioon "Pilved", Viru väljakul Edgar Viiese skulptuur "Merepiiga" (1981)

PHYSICAL AND CHEMICAL CHARACTERISTICS OF WHOLE RICE, BROKEN RICE, AND SOYBEAN EXTRACTS CARACTERÍSTICAS FÍSICO-QUÍMICAS DE EXTRATOS DE ARROZ INTEGRAL, QUIRERA DE ARROZ E SOJA

Directory of Open Access Journals (Sweden)

Priscila Zaczuk Bassinello

2011-07-01

Full Text Available

lang="pt-BR">lang="pt-BR">Hydrosoluble extracts are vegetable drinks with a commercial nutritional appeal, concerning health aspects, like absence of animal fats and high minerals contents. This study aimed to compare the physical and chemical characteristics of whole rice, broken rice, and soybean hydrosoluble extracts. The analyses (in triplicate were pH, soluble solids content, moisture, ashes, proteins, lipids, total carbohydrates, calcium, magnesium, cupper, manganese, iron, zinc, and caloric value. The broken rice extract presented the highest carbohydrates content (3.17 g 100 g^{lang="pt-BR">-1}lang="pt-BR"> and the lowest value for ashes (0.58 g 100 g^{lang="pt-BR">-1}Geochronology and geochemistry of the Niujuanzi ophiolitic mélange, Gansu Province, NW China: implications for tectonic evolution of the Beishan Orogenic Collage

Science.gov (United States)

Wang, Shengdong; Zhang, Kexin; Song, Bowen; Li, Shucai; Li, Ming; Zhou, Jie

2018-01-01

The Niujuanzi ophiolitic mélange (NOM), located in the Beishan Orogenic Collage, marks the termination between the Huaniushan arc and Mingshui-Hanshan Massifs. The NOM is mainly composed of gabbros, diabases, plagiogranites, basalts, and greywacke. Two gabbros have ages of 433.8 ± 3.1 and 354.0 ± 3.3 Ma, two plagiogranites have ages of 429.8 ± 2 and 448.7 ± 2.0 Ma, and a diabase has an age of 433.4 ± 3.2 Ma. The gabbros and diabases are calc-alkaline and tholeiitic, with high Al2O3, CaO, and TiO2 contents and low FeOT contents. The gabbros have high Mg# values (49-82), while the diabases have relatively low Mg# values (46-61). The plagiogranites are calc-alkaline and metaluminous, with high SiO2 and Na2O contents and low Al2O3 and K2O contents. The gabbros and diabases are enriched in large iron lithophile elements and slightly depleted in high field strength elements relative to N-MORB and their trace element characteristics are similar to E-MORB. With respect to rare earth element (REE), they have slightly enriched LREEs relative to HREEs. The majority of the plagiogranite trace elements approximate those of the volcanic arc granite. The plagiogranites have obviously enriched LREEs relative to HREEs, with a slightly to strongly negative Eu anomaly, which is similar to ORG but distinct from volcanic arc and within plate granite. The NOM was formed from the Ordovician to the Carboniferous, representing the expansion period of the Niujuanzi Ocean. The gabbros, diabases, and plagiogranites were formed in a mid-ocean ridge environment. The gabbros and diabases were generated by different degrees of partial melting of the mantle, and the plagiogranites derived from both the crystallization differentiation of basaltic magma and the partial melting of amphibolites in the crust.

narrative xml:lang="fr"

International Development Research Centre (IDRC) Digital Library (Canada)

The aim is to inform more effective violence prevention strategies that address ..... and violence by exploring how they provoke, sustain, and/or reduce these ...... the IDRC Corporate Strategy 2016-2020 and future programming areas of focus.

narrative xml:lang="fr"

International Development Research Centre (IDRC) Digital Library (Canada)

Le secteur des petites et moyennes entreprises (PME) représente près de 60 % du produit .... Pour être en mesure d'exercer une influence sur les politiques, ..... sur sa mise en oeuvre de la stratégie d'évaluation 2005-2010 qui mettra l'accent ...... le plan d'activités de même que la stratégie de recrutement et de promotion.

The Dora Lange Archive

DEFF Research Database (Denmark)

Holm, Isak Winkel; Bjering, Jens Christian Borrebye

2016-01-01

The first season of Nic Pizzolatto's True Detective (2014) is not only a show about a murder, but also a show about how to gather and organize information in an archive. Having identified two archival problems—its temporal and topical extension—the article turns to Jacques Derrida's Archive Fever......: a Freudian Impression in order to explain how the archiving problems of the crime investigation are, in fact, intrinsic to any archiving practice. Lastly, the article addresses the political significance of the show's archiving problems by help of Derrida's text on the American Constitution and of Hardt...

Kurbade naer / Anne Lange

Index Scriptorium Estoniae

Lange, Anne

1998-01-01

Ülevaade The Times Literary Supplement 21. aug. 1998 artiklitest: George Orwelli Kogutud teostest (toim. Peter Davidson, kirj. Secker and Warburg) ja Gillian Fenwicki koostatud G. Orwelli bibliograafiast (New Castle : Oak Knoll Books). Ka G. Orwelli tõlkimisest eesti keelde

Cornelia de Lange syndrome

DEFF Research Database (Denmark)

Boyle, M I; Jespersgaard, C; Brøndum-Nielsen, K

2015-01-01

, and hirsutism. Congenital anomalies include malformations of the upper limbs, gastrointestinal malformation/rotation, pyloric stenosis, diaphragmatic hernia, heart defects and genitourinary malformations. Gastroesophageal reflux disease is present in almost all patients. In addition to classic forms, milder...

Costly cables; Lange Leitung

Energy Technology Data Exchange (ETDEWEB)

Hautmann, Daniel

2012-08-15

Connection of offshore wind turbines to the onshore power supply grid requires costly cables for HV DC power transmission. The technology is mature enough to enable low-loss power transmission, but construction times may last several years.

narrative xml:lang="fr"

International Development Research Centre (IDRC) Digital Library (Canada)

The aim is threefold: to enhance the ability of rural communities to manage their ...... point des interventions communautaires afin de cibler les habitats des larves qui ...... But, while there is a rich literature exploring the impact of decentralization on ...... and high mortality in domestic poultry, waterfowl and other bird species.

Põhjamaade põlisvähemuste omakeelsest meediast / Mait Talts

Index Scriptorium Estoniae

Talts Mait, 1964-

2009-01-01

Artikkel jätkab Läänemere-äärsete etniliste vähemuskultuuride käsitlust. Vt. ka Haridus 5/6 2008, "Põlisvähemuskultuuride meediamaastikult" (latgalite, liivlaste, karaiimide, väikeleedulaste, kašuubide jt. omakeelse meedia hetkeolukorrast ja arenguperspektiividest)

Wallenbergide Investor jätkab kasvustrateegiat / Olev Mait Makk

Index Scriptorium Estoniae

Makk, Olev Mait

2001-01-01

Wallenbergide kontrollitavast Rootsi investeerimisfirmast Investor, mille omanduses olevad firmad moodustavad kokku Euroopa suurima tööandja erasektoris. Investori gruppi kuuluvast ettevõttest SEB. Tabel: Investori portfellis olevad aktsiad; investori teenused tütarettevõtetele

The singing revolution : part II-III / Mait Ando Raun

Index Scriptorium Estoniae

Raun, Mait, 1963-

2000-01-01

Tartu rahu ja vabariigi aastapäeva tähistamisest 1988. aastal; Sündmused veebruarist aprillini 1988: üliõpilaste demonstratsioonist veebruaris, Loominguliste Liitude ühispleenumist, Rahvarinde loomisest ja Tartu muinsuskaitsepäevadest aprillis. Järg nr.4, lk.70-73

Ma olen Turist, ma elan siin / Mait Väljas

Index Scriptorium Estoniae

Väljas, Mait

2006-01-01

Endise valuutapoe, praeguse klubi "Parlament" lammutamisplaanist Tallinnas Tartu mnt. 17. Arhitektid Peep Jänes ja Henno Sepmann, sisearhitekt Toivo Gans, sisekujundaja Aulo Padar. Ehitamisel osalesid ka soome arhitektid Kalle-Heiki Narinen ja Tapio Hänninen. Kommentaar Peep Jäneselt ja Aulo Padarilt

A novel KCNQ1 nonsense variant in the isoform-specific first exon causes both jervell and Lange-Nielsen syndrome 1 and long QT syndrome 1: a case report.

Science.gov (United States)

Nishimura, Motoi; Ueda, Marehiko; Ebata, Ryota; Utsuno, Emi; Ishii, Takuma; Matsushita, Kazuyuki; Ohara, Osamu; Shimojo, Naoki; Kobayashi, Yoshio; Nomura, Fumio

2017-06-08

According to previous KCNQ1 (potassium channel, voltage gated, KQT-like subfamily, member 1) gene screening studies, missense variants, but not nonsense or frame-shift variants, cause the majority of long QT syndrome (LQTS; Romano-Ward syndrome [RWS]) 1 cases. Several missense variants are reported to cause RWS by a dominant-negative mechanism, and some KCNQ1 variants can cause both Jervell and Lange-Nielsen Syndrome (JLNS; in an autosomal recessive manner) and LQTS1 (in an autosomal dominant manner), while other KCNQ1 variants cause only JLNS. The human KCNQ1 gene is known to have two transcript isoforms (kidney isoform and pancreas isoform), and both isoforms can form a functional cardiac potassium channel. Here, we report a novel nonsense KCNQ1 variant causing not only JLNS, but also significant QTc prolongation identical to RWS in an autosomal dominant manner. Our case study supports that haploinsufficiency in the KCNQ1 gene is causative of significant QTc prolongation identical to RWS. Interestingly, the nonsense variant (NM_000218.2:c.115G > T [p.Glu39X]) locates in exon 1a of KCNQ1, which is a kidney-isoform specific exon. The variant is located closer to the N-terminus than previously identified nonsense or frame-shift variants. To the best of our knowledge, this is the first report showing that a nonsense variant in exon 1a of KCNQ1, which is the kidney-isoform specific exon, causes JLNS. Our findings may be informative to the genetic pathogenesis of RWS and JLNS caused by KCNQ1 variants.

Behaviour of wild-type and genetically modified baculoviruses in the Helicoverpa armigera - cotton system: a simulation approach

NARCIS (Netherlands)

Sun, X.

2005-01-01

Keywords:   Helicoverpa armigera , baculovirus, genetic modification, cotton,lang=EN-US style='font-size:12.0pt; mso-ansi-language:EN-US;mso-fareast-language:ZH-CN;font-weight:normal'>transmissionlang=EN-US

Protein/polysaccharide complexes at air/water interfaces

NARCIS (Netherlands)

Ganzevles, R.A.

2007-01-01

KEYWORDS:lang=EN-GB>protein, polysaccharide,lang=EN-GB style='font-family: Symbol;mso-ascii-font-family:"Times New Roman";mso-hansi-font-family:"Times New Roman"; mso-char-type:symbol;mso-symbol-font-family:Symbol'>Exploring options for sustainable development of vegetable farms in South Uruguay

NARCIS (Netherlands)

Dogliotti Moro, S.

2003-01-01

Keywords:lang=EN-US>land use system, modeling, farming system, future-oriented studies, vegetables,

lang=EN-US>The sustainable development of vegetable farms in South Uruguay requires the development of farming systems that contribute

"aeg jookseb kiiresti nagu linnukoer..." : [luuletused] / Jaak Jõerüüt

Index Scriptorium Estoniae

Jõerüüt, Jaak, 1947-

2003-01-01

Sisu: "aeg jookseb kiiresti nagu linnukoer..." ; "hingele langes lund..." ; Eestis ; "minu esimesed luuletused sündisid siis kui vihma sadas..." ; "mina olen..." ; "kui Rooma jõudsin tabas mind masendus raske koorem langes õlgadele..." ; "Delfis jäi käimata, seal olevat hiilgav genius loci..."

The allocation of scarce resources in miscellaneous cases

NARCIS (Netherlands)

Hamsvoort, van der C.P.C.M.

2006-01-01

lang=EN-GB>Key wordslang=EN-GB>: sustainable development, environmental utilization space (EUS),      auctions, conservation contracting, information asymmetry, agricultural land

Essays on the economics of forestry-based carbon mitigation

NARCIS (Netherlands)

Benítez-Ponce, P.C.

2005-01-01

Keywords:lang=EN-US>climate change, carbon costs, afforestation, risk, secondary forests, conservation payments, ecosystem services

lang=EN-US>This thesis is a collection of articles that deal with the economics of carbon sequestration in forests. It pays

CRESCIMENTO DE FIGUEIRA SOB DIFERENTES CONDIÇÕES DE CULTIVO FIG TREE GROWTH UNDER DIFFERENT CROP CONDITIONS

Directory of Open Access Journals (Sweden)

Manoel Euzébio de Souza

2011-10-01

Full Text Available

lang="pt-BR">lang="pt-BR">A análise de crescimento de plantas pode ser considerada um bom indicativo para a avaliação das bases fisiológicas de produção e da influência exercida por variáveis ambientais, genéticas e agronômicas. Avaliou-se o crescimento da figueira ‘Roxo de Valinhos’, submetida a irrigação e cobertura morta (bagacilho de cana-de-açúcar triturado, em Botucatu (SP. O experimento utilizou blocos casualizados, em esquema fatorial 2x2 (cobertura morta x irrigação, com 4 repetições, sendo cada repetição constituída por 3 plantas, com caracterização dos seguintes tratamentos: T1 - sem irrigação e sem cobertura morta; T2 - sem irrigação e com cobertura morta; T3 - com irrigação e sem cobertura morta; T4 - com irrigação e cobertura morta. Foram realizadas análises destrutivas e não destrutivas, aos 7, 55, 76, 97, 114, 135, 156, 176, 198, 219, 240, 254 e 275 dias após o transplantio, com base nos seguintes parâmetros: diâmetro do ramo e do caule, comprimento do ramo, número de folhas, número de entrenós e número de frutos. Foram particionados os diferentes órgãos da planta, para obtenção da massa seca e fresca das partições isoladas. As medições da área foliar (cm^{lang="pt-BR">2}ORGANIC FERTILIZER AS PHOSPHORUS SUPPLIER FOR Brachiaria brizantha CV. MARANDÚ FERTILIZANTE ORGÂNICO COMO FONTE DE FÓSFORO NO CULTIVO INICIAL DE Brachiaria brizantha CV. MARANDÚ

Directory of Open Access Journals (Sweden)

Diego Henriques Santos

2010-05-01

Full Text Available

lang="pt-BR" align="JUSTIFY">Phosphorus is considered an essential element for plants, but it is found in low amounts in Brazilian soils, mainly in areas destined to pastures, and the application of organic matter contributes to the improvement of physical, chemical and biological soil attributes. The research had the objective of evaluating the application effects of the Bokashi organic compound on soil macro and micronutrients contents and leaves, as well as on Brachiaria brizantha cv. Marandú dry mass yield, evaluating the potential of the organic fertilizer as phosphorus source, in comparison with conventional chemical fertilizers. Different organic compound doses supplied the soil with 17 kg P₂O₅ ha^-1, 34 kg P₂O₅ ha^-1, 68 kg P₂O₅ ha^-1, 136 kg P₂O₅ ha^-1, and 204 kg P₂O₅ ha^-1, comparing it with the conventional chemical fertilizer and the control. The results revealed that the organic fertilizer Bokashi can adequately replace the conventional chemical fertilizer of Brachiaria brizantha cv. Marandú, supplying the soil and plant with appropriate nutrients levels and maintaining the dry mass yield.

lang="pt-BR" align="JUSTIFY">lang="en-US">KEY-WORDS: Organic matter; organic fertilizers; plants mineral nutrition; lang="pt-PT">Bokashilang

Irrigation Practices, State Intervention and Farmers' Life- Worlds in Drought-Prone Tigray, Ethiopia

NARCIS (Netherlands)

Teshome, W.

2003-01-01

This study examines irrigation practices, state intervention and the responses of farmers in theTigrayregion oflang=EN-US style='font-family:Palatino'>Ethiopialang=EN-US

Policy Recommendations : Enhancement of Cultural and Linguistic Variety through OER

NARCIS (Netherlands)

Bijlsma, M.; Titlestad, Gard; Creelman, Alastair

2016-01-01

Kleinere talen (Engels: Lesser UsedLanguages, LUL) vormen het middelpunt van het LangOER-project. In het kader van LangOER gaat het bij zulke ‘kleinere talen’ om bedreigde talen, regionale en minderheidstalen (ca. 10% van de Europese bevolking) en kleine nationale talen. Open leermiddelen (Open

Review: Mohamed Saliou Camara, Political History of Guinea since World War Two (2014)

OpenAIRE

Carole Ammann; University of Basel

2015-01-01

Review of the monograph:Mohamed Saliou Camara, Political History of Guinea since World War Two, New York: Peter Lang, 2014, ISBN 9781433122439, 531 pp. Besprechung der Monographie:Mohamed Saliou Camara, Political History of Guinea since World War Two, New York: Peter Lang, 2014, ISBN 9781433122439, 531 Seiten

Estimation of genotype × environment interaction for yield, health and fertility in dairy cattle

NARCIS (Netherlands)

Calus, M.P.L.

2006-01-01

In dairy cattle breeding,lang=EN-US style='font-size:12.0pt;line-height:130%; font-family:"Times New Roman";mso-ansi-language:EN-US'>health and fertility traits have recently been included in a large number of national breeding goals.lang=EN-US

Public safety risk management at socio-economic and / or historic-cultural significant dam sites

Energy Technology Data Exchange (ETDEWEB)

Earle, Gordon D.; Ryan, Katherine; Pyykonen, Nicole K.; Pitts, Lucas [Otonabee Region Conservation Authority, Peterborough, (Canada)

2010-07-01

The Lang Dam and adjoining gristmill, located near Peterborough are integral parts of the Lang Pioneer Village museum. Activities occurring within close proximity to the dam have led to safety issues. The owner (ORCA) has developed and implemented public safety management plans (PSMPs) for each of its water control structures, including the Lang Dam. ORCA gave special attention to the social, economic, aesthetic, historic and cultural dimensions associated the implementation of public safety management plans. These factors play a significant role in how well public safety measures (PSMs) are received by stakeholder groups and the general public. This paper reported the challenges of developing and implementing a PSMP for the Lang Dam, with the focus on property site-specific PSMS while preserving socio-economic and historic-cultural character and values. It was demonstrated that the dam owners, regulatory authorities, control agencies and preservationists need to come together to develop a holistic public safety management process.

SWEETS FORMULATED WITH MANGO SKIN DOCES DE CORTE FORMULADOS COM CASCA DE MANGA

Directory of Open Access Journals (Sweden)

Eduardo Valério de Barros Vilas Boas

2011-07-01

Full Text Available

lang="pt-BR">lang="pt-BR">Concerning the mango industrial processing,lang="pt-BR"> lang="pt-BR">skin islang="pt-BR"> lang="pt-BR">alang="pt-BR"> lang="pt-BR">disposal component

Políticas de Assentamento e Localidade. Os desáfios da reconstituicão do trabalho rural no Brasil

NARCIS (Netherlands)

Cabello Norder, L.A.

2004-01-01

The consolidation of the democratic institutions inlang=EN-GB style='font-size:12.0pt;mso-bidi-font-size:10.0pt;mso-ansi-language: EN-GB'>Brazillang=EN-GB

Signaling pathways involved in pathogenicity and development of the fungal wheat pathogen Mycosphaerella graminicola

NARCIS (Netherlands)

Mehrabi, R.

2006-01-01

Mycosphaerella graminicolalang=EN-US>(Fuckel) J. Schröt is the causal agent of septoria tritici leaf blotch, which is the major foliar wheat disease in most temperate areas.lang=EN-US>Direct losses and the cost of control strategies contribute to the huge economical

Planning and Designing Effective Defence and Related Information Services: Conference Proceedings of the Technical Information Panel Specialists’ Meeting Held in Ankara, Turkey on 10-11 September 1986.

Science.gov (United States)

1987-04-01

Is Defense, en alant au-doll de ce qua peut apporter un simple repertoire, commae celul du DTIC aux Etats-Unis (5). ii counvient donc de dhvelopper...en consultation mais devront etre exclus du prit. Maits touts laide qua h’on apportersa Al’utilisaeur, celul -ci perdra besucoup do tampa I cee...mains quoun systme do guichat ivolui. come celul dont il a iti question plus haut, soit jug& prifirable. 8-5 2.3. Sources primaires. Touts information

The African rain forest during the Last Glacial Maximum an archipelago of forests in a sea of grass

NARCIS (Netherlands)

Leal, M.E.

2004-01-01

In centrallang=EN-GB style='font-size:12.0pt;font-family:"Times New Roman";mso-ansi-language: EN-GB'>Gabonlang=EN-GB style='font-size:12.0pt;font-family:"Times New

Breeding success of Oystercatcher, terns and gulls in the Danish Wadden Sea

DEFF Research Database (Denmark)

Bregnballe, Thomas; Thorup, Ole; Jensen, Peter Emil

2015-01-01

breeding of Sandwich Terns was recorded on Langli in most of the years during 2006-2010. The Lesser Black-backed Gulls and Herring Gulls that nested on Langli were fairly successful in raising young to fledging during 2009-2013, whereas Common Gulls suffered from predation by Herring Gulls and they hardly...

En vakker vase af jern og stål: Michelle Yeoh

DEFF Research Database (Denmark)

Schubart, Rikke

2006-01-01

Artikel om den malaysiske skuespiller Michelle Yeoh og hendes action persona fra en lang række Hong Kong film og hendes senere internationale film.......Artikel om den malaysiske skuespiller Michelle Yeoh og hendes action persona fra en lang række Hong Kong film og hendes senere internationale film....

DIAGNÓSTICO DE LA COMPETENCIA PARA LA COMUNICACIÓN EN DIRECTIVOS QUE CURSAN LA MAESTRÍA EN DIRECCIÓN

Directory of Open Access Journals (Sweden)

Mónica Queris Rojas

2009-05-01

Full Text Available

lang="ES">El término gestión por competencias, crece en importancia en diversas partes del mundo, ocupando cada vez un papel más central en empresas y centros de educación superior. En este aspecto, las experiencias en América Latina, están mostrando que lo más importante no es quién certifica, sino cómo se desarrolla el proceso. En nuestro país su incorporación es aun mínima en términos reales, aunque algunas experiencias han sido introducidas en diversas organizaciones en el diseño de puestos de trabajo y ocupacionales lang="ES">[1]lang="ES">.

lang="ES">Este trabajo pretende demostrar un diagnóstico sobre la competencia para la comunicación en directivos que han cursado y cursan la maestría en Dirección a partir de la aplicación de diferentes técnicas.

Todd Berliner. Hollywood Incoherent. Narration in Seventies Cinema.

Directory of Open Access Journals (Sweden)

Pascal Lefèvre

2010-12-01

Full Text Available

lang="EN-GB">Todd Berliner. Hollywood Incoherent. Narration in Seventies Cinema.

lang="EN-GB">Austinlang="EN-GB">: University of Texas Press, 2010.

lang="EN-US">ISBN-10:lang="EN-US"> 0292722796 lang="EN-GB">

lang="EN-US">ISBN-13:lang="EN-US"> 978-0292722798 lang="EN-GB">