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Sample records for anniste mait lang

  1. Meie ei ole ajaloota rahvas... : lisandusi M. Ojamaa, A. ja T. Varmase Eesti ajaloo saamisloole / Sirje Annist

    Annist, Sirje

    2004-01-01

    Esimene eesti autorite koostatud Eesti ajaloo üldkäsitlus : M. Ojamaa, A. ja T. Varmas Viron historia, Porvoo, 1944. Tõlge eesti keelde 1946. aastal Stockholmis. Autoriteks pseudonüümide all kirjutanud kultuuritegelased : M. Ojamaa - Harri Moora, A. Varmas - August Annist, T. Varmas - Linda Annist

  2. Mait Laas : see oli intrigeeriv eksperiment / Mait Laas

    Laas, Mait, 1970-

    2006-01-01

    Kinos Sõprus on ekraanil Ida-Euroopa kuue noore režissööri filmiprojekt "Kaotatud ja leitud" ("Lost and Found"), mille seob tervikuks Mait Laasi nukufilm "Gene+Ratio". Režissöör räägib projektist lähemalt

  3. DOE contractor vulnerability analysis: DPA or MAIT

    Six, D.E.; Nichols, D.H.

    1980-01-01

    Two vulnerability analysis techniques, Diversion Path Analysis (DPA) and Matrix Analysis of the Insider Threat (MAIT), were applied by EG and G Idaho, Inc. Safeguards and Security to the same item accountable SNM storage area at INEL. Technical and cost data for each methodology were collected and compared. A recommendation that MAIT be utilized for future vulnerability analyses of item accountable SNM storage and use areas operated by EG and G Idaho for DOE-ID resulted. Unclassified results of the two techniques and MAIT/DPA technical and cost comparisons will be presented which show that MAIT can be used for vulnerability analyses to comply with Department of Energy (DOE) requirements

  4. Lange Bramke

    Hauhs, M.

    1989-01-01

    The forested catchment of Lange Bramke In the Harz Mountains (FRG) has been hydrologically monitored since 1948 when it was clear-cut. Today the catchment is covered by a 38-year-old Norway spruce (Picea abies Karst.) stand. Seepage water pathways through the catchment and ion cycling have been investigated in detail during the last 10 years. The results show that seepage water through the root zone is vertical and unsaturated at the catchment slopes. The derived model of seepage water trajectories matches the observed chemical gradients between soil solution, headwater, groundwater, and runoff

  5. Stepwise development of MAIT cells in mouse and human.

    Emmanuel Martin

    2009-03-01

    Full Text Available Mucosal-associated invariant T (MAIT cells display two evolutionarily conserved features: an invariant T cell receptor (TCRalpha (iTCRalpha chain and restriction by the nonpolymorphic class Ib major histocompatibility complex (MHC molecule, MHC-related molecule 1 (MR1. MR1 expression on thymus epithelial cells is not necessary for MAIT cell development but their accumulation in the gut requires MR1 expressing B cells and commensal flora. MAIT cell development is poorly known, as these cells have not been found in the thymus so far. Herein, complementary human and mouse experiments using an anti-humanValpha7.2 antibody and MAIT cell-specific iTCRalpha and TCRbeta transgenic mice in different genetic backgrounds show that MAIT cell development is a stepwise process, with an intra-thymic selection followed by peripheral expansion. Mouse MAIT cells are selected in an MR1-dependent manner both in fetal thymic organ culture and in double iTCRalpha and TCRbeta transgenic RAG knockout mice. In the latter mice, MAIT cells do not expand in the periphery unless B cells are added back by adoptive transfer, showing that B cells are not required for the initial thymic selection step but for the peripheral accumulation. In humans, contrary to natural killer T (NKT cells, MAIT cells display a naïve phenotype in the thymus as well as in cord blood where they are in low numbers. After birth, MAIT cells acquire a memory phenotype and expand dramatically, up to 1%-4% of blood T cells. Finally, in contrast with NKT cells, human MAIT cell development is independent of the molecular adaptor SAP. Interestingly, mouse MAIT cells display a naïve phenotype and do not express the ZBTB16 transcription factor, which, in contrast, is expressed by NKT cells and the memory human MAIT cells found in the periphery after birth. In conclusion, MAIT cells are selected by MR1 in the thymus on a non-B non-T hematopoietic cell, and acquire a memory phenotype and expand in the

  6. Johann de Lange

    Owner

    In hierdie elfde bundel van De Lange bevestig hy sy verdiende en gekanoniseerde posisie in die Afrikaanse dig- kuns, in besonder vanweë 'n volgehoue sig- baarmaking van verhoudinge tussen mens en kosmos; mens en medemens; besit en ver- lies; broosheid/verganklikheid/verwonding teenoor herstel en heelmaking.

  7. Luftkvalitet langs motorveje

    Jensen, S. S.; Løfstrøm, P.; Berkowicz, R.

    Denne rapport beskriver måle- og modelresultater. Målekampagnen blev gennemført langs Køge Bugt motorvejen ved Greve for en 3 måneders periode i efteråret 2003, hvor der blev målt NOx (NO og NO2) i forskellige afstande af motorvejen. Der er endvidere opstillet en luftkvalitetsmodel, som beskriver...

  8. MAIT application to the analysis of commercial power plants

    Goldman, L.A.; McDaniel, T.L.; Chapman, L.D.; Stack, D.

    1981-01-01

    This paper discusses a study which was conducted for the U.S. Nuclear Regulatory Commission (NRC) to determine the applicability of the Matrix Analysis of the Insider Threat (MAIT) code to the analysis of sabotage vulnerabilities of commercial power reactors. The sabotage of concern was the initiation of a release of radioactivity in excess of 10 CFR 100 guidelines. 5 refs

  9. Brachman de lange syndrome

    Leena Verma

    2010-01-01

    Full Text Available Brachman de Lange syndrome or Cornelia de Lange syndrome (CdLS is a genetic disorder which can lead to severe developmental anomalies. It affects both the physical and intellectual development of a child. It is characterized by skeletal, craniofacial deformities, gastrointestinal and cardiac malformations. This syndrome is of rare occurrence and affects between 1/10,000 and 1/60,000 neonates. Diagnosis is based on the characteristic phenotype, in particular, a striking facial appearance, prenatal and postnatal growth retardation, various skeletal abnormalities, hypertrichosis, and developmental delay. Here, we present the case of a 13-year-old patient, with micrognathia, delayed eruption, multiple carious teeth, missing teeth and periodontal problems together, which had never been reported before. The father was also found to have the same missing teeth as the girl child.

  10. Hobusega kiirrongi ei püüa / Mait Klaassen

    Klaassen, Mait, 1955-

    2002-01-01

    Ilmunud ka: Pärnu Postimees, Virumaa Teataja, Sakala, Vooremaa, Põhjarannik, Severnoje Poberezhje, Võrumaa Teataja, Valgamaalane, Koit, Lääne Elu 12. nov. lk. 7;4;4;3;5;5;3;4;3;2. Võru maavanem Mait Klaassen loodab, et liitumisel EL-iga läheb Eestil korda jõuda jõukale järjele ja samas säilitada iseseisvus

  11. MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection.

    Dominic Paquin-Proulx

    2018-01-01

    Full Text Available Dengue virus (DENV and Zika virus (ZIKV are members of the Flaviviridae and are predominantly transmitted via mosquito bites. Both viruses are responsible for a growing number of infections in tropical and subtropical regions. DENV infection can cause lethargy with severe morbidity and dengue shock syndrome leading to death in some cases. ZIKV is now linked with Guillain-Barré syndrome and fetal malformations including microcephaly and developmental disorders (congenital Zika syndrome. The protective and pathogenic roles played by the immune response in these infections is unknown. Mucosal-associated invariant T (MAIT cells are a population of innate T cells with potent anti-bacterial activity. MAIT cells have also been postulated to play a role in the immune response to viral infections. In this study, we evaluated MAIT cell frequency, phenotype, and function in samples from subjects with acute and convalescent DENV infection. We found that in acute DENV infection, MAIT cells had elevated co-expression of the activation markers CD38 and HLA-DR and had a poor IFNγ response following bacterial stimulation. Furthermore, we found that MAIT cells can produce IFNγ in response to in vitro infection with ZIKV. This MAIT cell response was independent of MR1, but dependent on IL-12 and IL-18. Our results suggest that MAIT cells may play an important role in the immune response to Flavivirus infections.

  12. Rein Lang : liitriiki ei tule / Rein Lang ; interv. Sten Hansson

    Lang, Rein, 1957-

    2003-01-01

    Ilmunud ka: Severnoje Poberezhje 16. juuli lk. 2, Lääne Elu 17. juuli lk. 4, Meie Maa 17. juuli lk. 2, Koit 17. juuli lk. 6, Vooremaa 17. juuli lk. 2, Hiiu Leht 22. juuli lk. 2, Nädaline 2. august lk. 4. Intervjuu Euroopa Liidu tulevikukonvendis osalenud Rein Lang'iga EL-i põhiseaduse projektist

  13. MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications.

    Paquin-Proulx, Dominic; Greenspun, Benjamin C; Costa, Emanuela A S; Segurado, Aluisio C; Kallas, Esper G; Nixon, Douglas F; Leal, Fabio E

    2017-01-01

    HTLV-1 infection is associated with several inflammatory disorders, including the neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). It is unclear why a minority of infected subjects develop HAM/TSP. The cellular immune response has been implicated in the development of inflammatory alterations in these patients; however the pathogenic mechanisms for disease progression remain unclear. Furthermore, HTLV-1-infected individuals have an increase incidence of Mycobacterium tuberculosis (Mtb) infection, suggesting that immunological defect are associated with HTLV-1 infection. Evidence suggests an important role for Mucosal-associated invariant T (MAIT) cells in the early control of Mtb infection. Chronic viral infections like HIV and HCV have been associated with decreased frequency and functionality of MAIT cells. We hypothesized that HTLV-1 infection is associated with similar perturbations in MAIT cells. We investigated MAIT cell frequency, phenotype, and function by flow cytometry in a cohort of 10 asymptomatic and 10 HAM/TSP HTLV-1 infected patients. We found that MAIT cells from HTLV-1-infected subjects were reduced and showed high co-expression of the activation markers CD38 and HLA-DR but normal levels of CCR6 and CD127. MAIT cells had a lower expression of the transcription factor PLZF in HAM/TSP patients. Unlike Tax-specific CD8+T cells, which are hyperfunctional, MAIT cells from HTLV-1-infected subjects had a poor IFNγ response following antigen stimulation. MAIT cell perturbations in HTLV-1 infection were not associated with HTLV-1 proviral load and MAIT cells were not infected by HTLV-1 in vivo. Rather, MAIT cells loss was associated with immune activation. Overall, our results do not support a role for MAIT cells in HAM/TSP pathogenesis but reduced numbers of MAIT cells, together with their poor functionality, could contribute to the increased susceptibility of HTLV-1-infected individuals to other infectious

  14. MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications.

    Dominic Paquin-Proulx

    Full Text Available HTLV-1 infection is associated with several inflammatory disorders, including the neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP. It is unclear why a minority of infected subjects develop HAM/TSP. The cellular immune response has been implicated in the development of inflammatory alterations in these patients; however the pathogenic mechanisms for disease progression remain unclear. Furthermore, HTLV-1-infected individuals have an increase incidence of Mycobacterium tuberculosis (Mtb infection, suggesting that immunological defect are associated with HTLV-1 infection. Evidence suggests an important role for Mucosal-associated invariant T (MAIT cells in the early control of Mtb infection. Chronic viral infections like HIV and HCV have been associated with decreased frequency and functionality of MAIT cells. We hypothesized that HTLV-1 infection is associated with similar perturbations in MAIT cells. We investigated MAIT cell frequency, phenotype, and function by flow cytometry in a cohort of 10 asymptomatic and 10 HAM/TSP HTLV-1 infected patients. We found that MAIT cells from HTLV-1-infected subjects were reduced and showed high co-expression of the activation markers CD38 and HLA-DR but normal levels of CCR6 and CD127. MAIT cells had a lower expression of the transcription factor PLZF in HAM/TSP patients. Unlike Tax-specific CD8+T cells, which are hyperfunctional, MAIT cells from HTLV-1-infected subjects had a poor IFNγ response following antigen stimulation. MAIT cell perturbations in HTLV-1 infection were not associated with HTLV-1 proviral load and MAIT cells were not infected by HTLV-1 in vivo. Rather, MAIT cells loss was associated with immune activation. Overall, our results do not support a role for MAIT cells in HAM/TSP pathogenesis but reduced numbers of MAIT cells, together with their poor functionality, could contribute to the increased susceptibility of HTLV-1-infected individuals to

  15. Cornelia de Lange Syndrome Foundation

    ... Outside Links Privacy & Terms Site Map The Cornelia de Lange Syndrome (CdLS) Foundation is a family support organization that ... research into the causes and manifestations of the syndrome, and help people with a diagnosis of CdLS make informed decisions throughout their lives.

  16. Lange »krigsballetter«

    Petersen, Hanne

    2016-01-01

    Artiklen undersøger Den Westfalske Fred (1648) og Tredveårskrigen (den lange krigsballet) i lyset af nutidige langvarige krigsballetter, der foreløbig har karakteriseret det meste af det 21. århundrede. Begge er fragmenterede, brutale, kyniske, og karakteriseret af reseksualiseret voldsanvendelse...

  17. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

    Gold, Marielle C.; McLaren, James E.; Reistetter, Joseph A.

    2015-01-01

    with this interpretation, MAIT cell clones with distinct TCRs responded differentially to a riboflavin metabolite. These results suggest that MAIT cells can discriminate between pathogen-derived ligands in a clonotype-dependent manner, providing a basis for adaptive memory via recruitment of specific repertoires shaped...

  18. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

    Gold, Marielle C.; McLaren, James E.; Reistetter, Joseph A.

    2014-01-01

    Mucosal-associated invariant T (MAIT) cells express a semi-invariant T cell receptor (TCR) that detects microbial metabolites presented by the nonpolymorphic major histocompatibility complex (MHC)-like molecule MR1. The highly conserved nature of MR1 in conjunction with biased MAIT TCRα chain usa...

  19. Märt Agu käib isa Mait Agu jälgedes / Heili Sibrits

    Sibrits, Heili, 1977-

    2001-01-01

    Koreograafi ja tantsupedagoogi Mait Agu poeg Märt Agu on Eesti Tantsuagentuuri tantsija ja Pedagoogilise Instituudi tantsujuhtimise viimase kursuse üliõpilane, kes esineb revüüteatris "Bel-⁹tage"

  20. Pankur poris / Aet Annist

    Annist, Aet

    2008-01-01

    Autor annab ülevaate ajalehe Financial Times kolumnisti Gillian Tetti artiklist, kus räägitakse sellest, et tänases pangandusettevõtete segaduses maksab jälgida ka panganduse esindajate kui professionaalse grupi enesekehtestamist ja selle läbikukkumist. Vt. ka Financial Times, 18.01.2008

  1. Langi retseptid majanduse restartimiseks / Rein Lang

    Lang, Rein, 1957-

    2008-01-01

    Justiitsminister Rein Lang selgitab Maksumaksjale majanduse taaskäivitamise ideid, millest oli juttu 15. nov. 2008. aasta Reformierakonna majanduskonverentsil Restart ja Äripäev Onlines (15.11.2008)

  2. Taifuun nimega Valimised on möödas / Mait Klaassen

    Klaassen, Mait, 1955-

    2005-01-01

    Ilmunud ka: Põhjarannik 20. okt., lk. 2, Severnoje Poberezhje 20. okt., lk. 2, Meie Maa 20. okt., lk. 2, Sakala 21. okt., lk. 2, Vali Uudised 21. okt. lk. 2, Koit, Järva Teataja 22. okt. lk. 6,2, Lääne Elu 25. okt., lk. 2, Harjumaa 25. okt. lk. 2, Vooremaa 27. okt. lk. 2. Parlamendisaadik, Reformierakonna liige Mait Klaassen teeb kokkuvõtte lõppenud kohalikest valimistest

  3. CD161+ MAIT cells are severely reduced in peripheral blood and lymph nodes of HIV-infected individuals independently of disease progression.

    Johanna Maria Eberhard

    Full Text Available Mucosal-associated invariant T (MAIT cells are characterized by the combined expression of the semi-invariant T cell receptor (TCR Vα7.2, the lectin receptor CD161, as well as IL-18R, and play an important role in antibacterial host defense of the gut. The current study characterized CD161(+ MAIT and CD161-TCRVα7.2(+ T cell subsets within a large cohort of HIV patients with emphasis on patients with slow disease progression and elite controllers. Mononuclear cells from blood and lymph node samples as well as plasma from 63 patients and 26 healthy donors were analyzed by multicolor flow cytometry and ELISA for IL-18, sCD14 and sCD163. Additionally, MAIT cells were analyzed after in vitro stimulation with different cytokines and/or fixed E.coli. Reduced numbers of CD161(+ MAIT cells during HIV infection were detectable in the blood and lymph nodes of all patient groups, including elite controllers. CD161+ MAIT cell numbers did not recover even after successful antiretroviral treatment. The loss of CD161(+ MAIT cells was correlated with higher levels of MAIT cell activation; an increased frequency of the CD161-TCRVα7.2(+T cell subset in HIV infection was observed. In vitro stimulation of MAIT cells with IL-18 and IL-12, IL-7 and fixed E.coli also resulted in a rapid and additive reduction of the MAIT cell frequency defined by CD161, IL-18R and CCR6. In summary, the irreversible reduction of the CD161(+ MAIT cell subset seems to be an early event in HIV infection that is independent of later stages of the disease. This loss appears to be at least partially due to the distinctive vulnerability of MAIT cells to the pronounced stimulation by microbial products and cytokines during HIV-infection.

  4. The dynamical Mordell-Lang conjecture

    Bell, Jason P; Tucker, Thomas J

    2016-01-01

    The Dynamical Mordell-Lang Conjecture is an analogue of the classical Mordell-Lang conjecture in the context of arithmetic dynamics. It predicts the behavior of the orbit of a point x under the action of an endomorphism f of a quasiprojective complex variety X. More precisely, it claims that for any point x in X and any subvariety V of X, the set of indices n such that the n-th iterate of x under f lies in V is a finite union of arithmetic progressions. In this book the authors present all known results about the Dynamical Mordell-Lang Conjecture, focusing mainly on a p-adic approach which provides a parametrization of the orbit of a point under an endomorphism of a variety.

  5. Seabed sets the pace for Ormen Lange

    Knott, T.

    2001-01-01

    The article describes Norway's Ormen Lange development with its 400 billion cubic metres of gas reserves. Its strategic importance is two-fold: (i) it will provide the infrastructure for Norway to unlock a new offshore region in mid-Norway and (ii) for Europe, it will coincide with an expected shortfall in gas supplies at a time of increasing energy demand. Ormen Lange is expected to be the driver for new gas developments for Norway in terms of production and exports. The Ormen Lange reservoir is 1900m below the seabed where the water depth is 800-1100m. At present, Norsk Hydro (the operator) is considering three main development options for the field's facilities and each is described. The seabed terrain presents some of the most difficult problems the industry has ever tackled

  6. Anne-Mette Langes plan for ADHD kongressen

    Lange, Anne-Mette

    2017-01-01

    http://medicinsktidsskrift.dk/behandlinger/psykiatri/699-anne-mette-langes-plan-for-adhd-kongressen.html......http://medicinsktidsskrift.dk/behandlinger/psykiatri/699-anne-mette-langes-plan-for-adhd-kongressen.html...

  7. The Brachmann-De Lange Syndrome

    1974-05-04

    May 4, 1974 ... Two patients with the Brachmann-De Lange syndrome are described. The condition is not uncommon and is ... infection with difficulty in sucking and the child did not take feeds well during the whole of the first ... the right fifth finger was due to hypoplasia of the middle phalanx. The patient remained severely ...

  8. Social Anxiety in Cornelia de Lange Syndrome

    Richards, Caroline; Moss, Jo; O'Farrell, Laura; Kaur, Gurmeash; Oliver, Chris

    2009-01-01

    In this study we assessed the behavioral presentation of social anxiety in Cornelia de Lange syndrome (CdLS) using a contrast group of Cri du Chat syndrome (CdCS). Behaviors indicative of social anxiety were recorded in twelve children with CdLS (mean age = 11.00; SD = 5.15) and twelve children with CdCS (8.20; SD = 2.86) during social…

  9. Neuroimaging features of Cornelia de Lange syndrome

    Whitehead, Matthew T. [Department of Radiology, Washington, DC (United States); Nagaraj, Usha D. [Department of Radiology, Washington, DC (United States); Cincinnati Children' s Hospital, Department of Radiology, Cincinnati, OH (United States); Pearl, Phillip L. [Department of Radiology, Washington, DC (United States); Boston Children' s Hospital, Department of Neurology, Boston, MA (United States)

    2015-08-15

    Cornelia de Lange syndrome is a rare genetic disease characterized by distinctive facial dysmorphia and dwarfism. Multiple organ system involvement is typical. Various central nervous system (CNS) aberrations have been described in the pathology literature; however, the spectrum of neuroimaging manifestations is less well documented. To present neuroimaging findings from a series of eight patients with Cornelia de Lange syndrome. The CT/MR database at a single academic children's hospital was searched for the terms ''Cornelia'', ''Brachmann'' and ''de Lange.'' The search yielded 18 exams from 16 patients. Two non-CNS and six exams without available images were excluded. Ten exams from eight patients were evaluated by a board-certified neuroradiologist. All patients had skull base dysplasia, most with an unusual coronal basioccipital cleft (7/8). All brain MR exams showed microcephaly, volume loss and gyral simplification (5/5). Six patients had an absent massa intermedia. Four patients had small globe anterior segments; three had optic pathway hypoplasia. Basilar artery fenestration was present in two patients; vertebrobasilar hypoplasia was present in one patient. The inner ear vestibules were dysplastic in two patients. One patient had pachymeningeal thickening. Spinal anomalies included scoliosis, segmentation anomalies, endplate irregularities, basilar invagination, foramen magnum stenosis and tethered spinal cord. Typical imaging manifestations of Cornelia de Lange syndrome include skull base dysplasia with coronal clival cleft, cerebral and brainstem volume loss, and gyral simplification. Membranous labyrinth dysplasia, anterior segment and optic pathway hypoplasia, basilar artery fenestration, absent massa intermedia and spinal anomalies may also be present. (orig.)

  10. Neuroimaging features of Cornelia de Lange syndrome

    Whitehead, Matthew T.; Nagaraj, Usha D.; Pearl, Phillip L.

    2015-01-01

    Cornelia de Lange syndrome is a rare genetic disease characterized by distinctive facial dysmorphia and dwarfism. Multiple organ system involvement is typical. Various central nervous system (CNS) aberrations have been described in the pathology literature; however, the spectrum of neuroimaging manifestations is less well documented. To present neuroimaging findings from a series of eight patients with Cornelia de Lange syndrome. The CT/MR database at a single academic children's hospital was searched for the terms ''Cornelia'', ''Brachmann'' and ''de Lange.'' The search yielded 18 exams from 16 patients. Two non-CNS and six exams without available images were excluded. Ten exams from eight patients were evaluated by a board-certified neuroradiologist. All patients had skull base dysplasia, most with an unusual coronal basioccipital cleft (7/8). All brain MR exams showed microcephaly, volume loss and gyral simplification (5/5). Six patients had an absent massa intermedia. Four patients had small globe anterior segments; three had optic pathway hypoplasia. Basilar artery fenestration was present in two patients; vertebrobasilar hypoplasia was present in one patient. The inner ear vestibules were dysplastic in two patients. One patient had pachymeningeal thickening. Spinal anomalies included scoliosis, segmentation anomalies, endplate irregularities, basilar invagination, foramen magnum stenosis and tethered spinal cord. Typical imaging manifestations of Cornelia de Lange syndrome include skull base dysplasia with coronal clival cleft, cerebral and brainstem volume loss, and gyral simplification. Membranous labyrinth dysplasia, anterior segment and optic pathway hypoplasia, basilar artery fenestration, absent massa intermedia and spinal anomalies may also be present. (orig.)

  11. Obituary: Andrew Lange (1957-2010)

    Kamionkowski, Marc

    2011-12-01

    The worlds of physics and astrophysics were stunned to learn on 22 January 2010 that Andrew Lange, the Marvin L. Goldberger Professor of Physics at Caltech, had taken his own life the night before. He had succumbed to the severe depression that he had suffered from for many years, unbeknownst to even his closest colleagues. Lange will perhaps be best remembered as the co-leader of Boomerang, the balloon-borne experiment that provided the first high-angular-resolution map of the cosmic microwave background (CMB). And while this was certainly his most notable achievement, Andrew amassed a record of accomplishment as an instrumentalist, leader, mentor, and communicator that extended much further. Andrew was born in Urbana, Illinois on July 23, 1957, the son of an architect and a librarian, and raised primarily in Connecticut. His family and early friends remember him as a serious and extremely intelligent child and young man. Andrew Lange's lifelong interest in the CMB was nurtured as an undergraduate at Princeton University by David Wilkinson, and he recalled fondly a summer spent working with John Mather at Goddard Space Flight Center. Andrew Lange went to graduate school in physics at Berkeley where he worked in Paul Richards' group. Although his thesis project, the Berkeley-Nagoya rocket experiment, showed an anomalous sub-millimeter excess in the CMB spectrum that was shortly thereafter shown by a later flight of the same rocket and COBE-FIRAS to be incorrect, Lange's talents were recognized by the physics department at Berkeley who appointed him shortly after his PhD (1987) to their faculty. While on the Berkeley faculty, Andrew obtained early detections of the Sunyaev-Zeldovich effect, upper limits to small-angle CMB fluctuations, and important infrared constraints to the interstellar medium. He also led a pioneering instrument operating 300 mK detectors for a small infrared satellite experiment. This early work showed high ambition and daring, and it pioneered

  12. Ormen Lange subsea development strategy and execution

    Hogmoen, K. [Norsk Hydro, Oslo (Norway)

    2007-07-01

    Ormen Lange is the largest natural gas field in development on the Norwegian continental shelf. This paper discussed Norsk Hydro's Ormen Lange development strategy and execution. Several illustrations of the Ormen Lange project were presented, including the field layout and the main challenges of working in deep water. Other challenges involve environmental conditions; long distance control; and hydrate prevention. Several components of the project were presented, including the xmas tree handling system; choke module; control system; large bore tie-in system; in-line tee system; and free spans in pipeline design. Other topics that were presented and illustrated included the feasibility of pipeline design; design optimization with installation contractors; design optimization between intervention methods; positioning; dredging with spiders; excavation with jetprops; ploughing; rock installation; and trenching. The installation of thirty inch pipelines and umbilical lines in shallow and deep water were also discussed and illustrated. The presentation concluded with a discussion of lessons learned subsea. These included early definition of operational requirements; close monitoring of interface work between contractors; professional change management; and thorough testing onshore prior to installation. Securing vessel capacity and timely start-up were among the lessons learned for marine operations. figs.

  13. HIV infection is associated with preservation of MAIT cells in the lungs but alteration of their phenotype and T cell receptor repertoire

    Wong, E. B.; Xulu, B.; Prakadan, S.

    2016-01-01

    Tuberculosis remains the leading cause of death in HIV-positive people. A better understanding of the impact of HIV on lung immunity may lead to novel immunotherapeutic interventions. MAIT cells are tissue-homing donor-unrestricted T cells with broad anti-microbial activity. HIV infection causes ...... to determine the mechanisms underlying the altered phenotypes of lung-resident MAITs and whether these can be targeted to improve anti-microbial lung immunity in people living with HIV....

  14. Environmental Survey at Ormen Lange, June 2009

    Mannvik, Hans-Petter; Wasbotten, Ingar Halvorsen; Cochrane, Sabine

    2010-07-01

    An environmental monitoring survey was carried out at Ormen Lange in Region V on behalf of Norske Shell. The samples were collected at 19 stations by use of a 0.25 m{sub 2} box corer and carried out in connection with the field work in Region VI. The station depths varied between 823 and 925 m. The sediments at Ormen Lange are classified as silt with a high amount of pelite (> 90 %) and TOM (> 9 %). The amount of pelite is higher than that found in the baseline survey in 2004 at all stations. Whether this is a result of changes in sediment composition or a difference in analytical methods used is not known. With the exception of station OL-01 and OL-09, where a small increase has occurred, the amount of TOM has decreased at the stations since 2004. The concentrations of hydrocarbons and metals in the sediments at Template D, can be regarded as the natural background level for these parameters. The average amount of THC in the sediments around Template D is 11.7 +- 1.8 mg/kg in this base line survey. The average level of THC at template A and B was at the same level in the base line survey in 2004, 9.7 +- 0.6 mg/kg. In the present survey the average amount of THC in the sediments at Template A and B has increased to 17.0 +- 3.9 mg/kg. 11 of 14 stations at Template A and B have slightly elevated levels of barium and zinc in the sediments and sediments at three stations are elevated with mercury. In the present survey the mollusks dominates the fauna at Ormen Lange. The number of individuals at the stations (0.4 m{sub 2}) is high (1553 - 2833), while the number of taxa is relatively low (51 - 73), resulting in a very low diversity (H' 2.4 - 3.3). This is due to the over dominance by two mussels (Thyasira minuta and T. equalis) at all stations. However, the dominant species registered are known to be abundant in sediment with high amount of pelite and organic material. Due to the different sampling strategy and area, a direct comparison with the baseline survey is

  15. Isepäine modernist Toomas Rein / Toomas Rein ; intervjueerinud Mait Väljas ja Reet Varblane

    Rein, Toomas, 1940-

    2010-01-01

    23. aprillil avatakse Eesti Arhitektuurimuuseumis arhitekt Toomas Reinu 70. sünnipäevale pühendatud näitus. Kataloogi ja näituse on koostanud Toomas Rein ja Mait Väljas, kujundanud Tiit Jürna. Toomas Rein endast, oma loomingust, eeskujudest, näitusest, nõukogude perioodi hoonete olukorrast, viimase aja töödest, koostööst teiste arhitektidega, teostamata projektidest

  16. Planeerimine Fordi nimel / Aet Annist

    Annist, Aet

    2007-01-01

    Püüe muuta planeerimisega inimeste käitumist on sageli juba ette läbikukkumisele määratud. Näiteks toodud 1960. aastatel rajatud Milton Keynesi rattateede võrgustikuga aedlinn, kus elanikud kasutavad peamiselt autosid, nõukogude võimu ajal püstitatud köögita elamud, Rio de Janeiro slummielanikele isetekkeliste hüttide asemele püstitatud korterelamud, kus elamistingimused halvenesid

  17. MAIT, MR1, microbes and riboflavin: a paradigm for the co-evolution of invariant TCRs and restricting MHCI-like molecules?

    Mondot, Stanislas; Boudinot, Pierre; Lantz, Olivier

    2016-08-01

    MAIT cells express an invariant TCR that recognizes non-peptidic microbial antigens presented by the non-polymorphic MHCI-like molecule, MR1. We briefly describe how the antigens recognized by MAIT cells are generated from an unstable precursor of the riboflavin (Vitamin B2) biosynthesis pathway, as well as the main features of MAIT cells in comparison with other related T cell subsets. In silico analysis of bacterial genomes shows that the riboflavin biosynthesis pathway is highly prevalent in all groups of Prokaryotes with, however, notable exceptions. We discuss the putative functions and the evolution of the MAIT/MR1 couple: it appeared in the ancestors of mammals and is highly conserved across this group, but was independently lost in three orders. We describe the four instances of known invariant TCR and MHC-I-like molecules encountered in Vertebrates. Both T cells bearing semi-invariant TCR and the associated, evolutionarily conserved MHC-I related molecules have been found in mammals or in amphibians, which suggests that other MHC1-like/invariant TCR couples might be present in other classes of Vertebrates to detect generic microbial compounds. This allows us to discuss how the recognition of riboflavin precursor derivatives by the MAIT TCR may be a way to detect invasive microbes in specific organs, and may epitomize other invariant T cell systems across vertebrates.

  18. Cornelia de Lange Syndrome: Evolution of the Phenotype

    Passarge, Eberhard; And Others

    1971-01-01

    The medical case history of a 2-year-old girl who developed, during the second year of life, the classical phenotype (typical appearance) indicative of the deLange syndrome, with both mental and physical impairment. (KW)

  19. Genetics Home Reference: Jervell and Lange-Nielsen syndrome

    ... Home Edition for Patients and Caregivers: Long QT Syndrome and Torsades de Pointes Ventricular Tachycardia Orphanet: Familial long QT syndrome Orphanet: Jervell and Lange-Nielsen syndrome Patient Support ...

  20. Descriptive epidemiology of Cornelia de Lange syndrome in Europe

    Barisic, Ingeborg; Tokic, Visnja; Loane, Maria

    2008-01-01

    Cornelia de Lange syndrome (CdLS) is a multiple congenital anomaly/mental retardation syndrome consisting of characteristic dysmorphic features, microcephaly, hypertrichosis, upper limb defects, growth retardation, developmental delay, and a variety of associated malformations. We present...

  1. Ormen Lange hot tap - a world record

    Apeland, Kjell Edvard

    2010-07-01

    For the last 10 years Statoil have been developing a new concept for performing subsea Hot Tap operations remotely controlled. The system was first used offshore in 2008 during a partly diver assisted operation, connecting the Tampen Link pipeline to the Statfjord Intrafield pipeline. In July 2009, the Hot Tap System successfully performed two remotely controlled Hot Taps, on a world record depth of 860 meters on the Ormen Lange field operated by Shell. The Hot Tap technology enables existing pipeline architecture to be modified, without interfering with the current production. Most of the technology is depth independent and the system is currently qualified to 1000 meter depth. Phase II of this project which involves development and construction of a retrofit Tee, thus enabling installation and welding of a Tee on an unprepared pipeline is well underway. This presentation will describe experiences from the development of the Remote Hot Tap system and give an overview of the offshore operations leading to the conclusion of the world's deepest Hot Taps. (Author)

  2. Kaj Ulrik Linderstrøm-Lang (1896-1959).

    Schellman, J A; Schellman, C G

    1997-05-01

    The Carlsberg Laboratory in Copenhagen has had a long tradition of outstanding science. At the time covered by this discussion, Kjeldahl, Sørensen, and Linderstrøm-Lang had been consecutive directors of the Chemical Laboratory for 83 years. Lang's inspired leadership began in the 1930s with a number of innovations (study of metabolism in single cells, titrations in non-aqueous solvents, relation of proteolysis to structure) but it was not until the early 1950s that Denmark had sufficiently recovered from the war for the laboratory to enter world science again. During World War II, Lang had been active in the Danish resistance movement. After the war, a number of major advances were being made that would revolutionize the field of protein chemistry (Pauling and Corey's H-bonded structures, Sanger's sequencing techniques, chromatography, Watson and Crick structures, modern instrumentation). The time for the new field of the physical biochemistry of proteins had arrived. Lang, with his broad experience, adventurous spirit, and genius for innovation, created an environment that was ideal for the convergence of these disconnected advances into a uniform science. The emphasis was to be on quantitative measurements on proteins in solution with interpretations based on molecular structures. During an all-too-brief period of time, Lang's laboratory attracted a large fraction of those who were destined to be the leaders of the next generation of protein chemists. At this time, the Carlsberg Laboratory was probably the most scientifically exciting environment for a protein chemist. The methods developed at that time-hydrogen exchange, limited proteolysis, optical rotatory dispersion, volume changes accompanying protein reactions, automatic titrations-are still all in common use and many of the visitors to the laboratory in that period and their students are still playing major roles in protein research. Lang's other qualities should not be ignored. He was not only a great

  3. The SLANG/CIAO Synergy: Using S-Lang within CIAO

    Germain, G.; Milaszewski, R.; McLaughlin, W.; Miller, J.

    2004-07-01

    The integration of S-Lang into the Chandra Interactive Analysis of Observations (CIAO) infrastructure has transformed the capabilities of CIAO. There are several ways to use S-Lang. One is to write a S-Lang function which can be called from C/C++, CIAO applications, or any S-Lang prompt. Another is to write a C/C++ program which is made into a S-Lang intrinsic, allowing it to be called from any S-Lang script. The key element is that a C/C++ or CIAO application can call a S-Lang function/intrinsic, and that a S-Lang function/intrinsic can call a C/C++ or CIAO application. To use this capability, data must be exchanged between the C/C++ space and S-Lang space. This paper describes some of the mechanisms available for that data exchange. These mechanisms are illustrated through simple C/C++ and S-Lang program pairs, the S-Lang intrinsic methodology used by the CIAO S-Lang function ``univar'', and the use of the VARMM library by CIAO functions: Chandra Imaging and Plotting Software (ChIPS) UNIVAR, and the Graphical File Browser (PRISM) ``histogram''.

  4. Ants Orasest ja Anne Lange monograafiast / Jüri Talvet

    Talvet, Jüri, 1945-

    2005-01-01

    Arvustus: Oras, Ants. Luulekool. I, Apoloogia / koostajad Hando Runnel ja Jaak Rähesoo. Tartu : Ilmamaa, 2003 ; Oras, Ants. Luulekool II, Meistriklass. Tartu : Ilmamaa, 2004 ; Lange, Anne. Ants Oras : [kirjandusteadlane, -kriitik ja tõlkija (1900-1982)]. Tartu : Ilmamaa, 2004

  5. Characteristics of Autism Spectrum Disorder in Cornelia de Lange Syndrome

    Moss, Jo; Howlin, Patricia; Magiati, Iliana; Oliver, Chris

    2012-01-01

    Background: The prevalence of autism spectrum disorder (ASD) symptomatology is comparatively high in Cornelia de Lange syndrome (CdLS). However, the profile and developmental trajectories of these ASD characteristics are potentially different to those observed in individuals with idiopathic ASD. In this study we examine the ASD profile in CdLS in…

  6. Self-Injury in the De Lange Syndrome.

    Singh, N. N.; Pulman, Ruth M.

    1979-01-01

    Psychological treatment techniques for the control of self-injury in a 13-year-old male with de Lange syndrome (a rare disorder characterized by retarded mental and physical development) are presented. Techniques, which included mild punishment, time out, and differential reinforcement, produced a clinically significant control of self-injurious…

  7. T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis.

    Held, Kathrin; Beltrán, Eduardo; Moser, Markus; Hohlfeld, Reinhard; Dornmair, Klaus

    2015-09-01

    Mucosal-associated invariant T (MAIT) cells are a T-cell subset that expresses a conserved TRAV1-2 (Vα7.2) T-cell receptor (TCR) chain and the surface marker CD161. They are involved in the defence against microbes as they recognise small organic molecules of microbial origin that are presented by the non-classical MHC molecule 1 (MR1). MAIT cells express a semi-restricted TCR α chain with TRAV1-2 preferentially linked to TRAJ33, TRAJ12, or TRAJ20 which pairs with a limited set of β chains. To investigate the TCR repertoire of human CD161(hi)TRAV1-2(+) T cells in depth we analysed the α and β chains of this T-cell subset by next generation sequencing. Concomitantly we analysed 132 paired α and β chains from single cells to assess the αβ pairing preferences. We found that the CD161(hi)TRAV1-2(+) TCR repertoire in addition to the typical MAIT TCRs further contains polyclonal elements reminiscent of classical αβ T cells. Copyright © 2015 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

  8. Cornelia de-Lange syndrome - A case report

    Charvi Chawla

    2018-01-01

    Full Text Available Cornelia de-Lange syndrome (CdLS is a rare multisystem developmental disorder characterized by psychomotor retardation and delayed growth associated with a series of malformations, including facial dysmorphia, upper-extremity malformations, hirsutism, cardiac defects, and gastrointestinal abnormalities. There is no definitive biochemical or chromosomal marker for the prenatal diagnosis of syndrome so it is important for the clinician to know etiopathological aspects and characteristic features to provide health care and help improve the quality of life of affected individuals.

  9. Doktoritööd : [2007, Anne Lange jt.

    2007-01-01

    20. veebr. kaitseb Anne Lange doktoritööd "The poetics of translation of Ants Oras". 19. jaan. kaitses Tuuli Oder doktoritööd "The model of contemporary professional foreign language teacher". 16. jaan. kaitses Tiit Maran doktoritööd "Conservation biology of the European mink, Mustela lutreola (Linnaeus 1761): decline and causes of extinction". 12. jaan. kaitses Maris Saagpakk doktoritööd "Deutschbaltische Autobiographien als Dokumente des Zeit- und Selbstempfindens: vom Ende des 19. Jh. bis zur Umsiedlung 1939"

  10. Tähed disainiöös / Mait Summatavet, Risto Räägel, Per Mollerup...[jt.] ; interv. Karin Paulus

    2007-01-01

    Disainiöö raames avati Arhitektuuri- ja Disainigaleriis näitus "Kokkupandavad asjad" ning kuulutati välja konkursi võitjad. Peapreemia võitis läti disaineri Elina Bushmane kokkupandav teelaud, teise koha Jaana Päeva tekstiilist kott, kolmanda koha Ingrem Floreni käekott. Ära märgiti Veiko Liisi kilepiima vutlar. Disainiöö üritustest ning konkursitöödest räägivad Mait Summatavet, Per Mollerup, Simo Heikkilä, Risto Räägel

  11. Half-Forgotten Personalities of Economic Thought – O. R. Lange

    Pavel Sirůček

    2017-03-01

    Full Text Available O. R. Lange, a Polish economist, statistician, econometrician, sociologist, politician and diplomat was classified as a reformist Marxist. He became famous for studies on planning and socialist economies. Lange demonstrates and proves the possibility of the existence of an effective socialist system. He also analyzed capitalist economy, e.g., the issue of cyclical fluctuations and unemployment.

  12. The Association Between Environmental Events and Self-Injurious Behaviour in Cornelia de Lange Syndrome

    Moss, J.; Oliver, C.; Hall, S.; Arron, K.; Sloneem, J.; Petty, J.

    2005-01-01

    There has been limited empirical research into the environmental causes of self-injury in Cornelia de Lange syndrome. The present study examined the variability of self-injurious behaviour in Cornelia de Lange syndrome across environmental setting events. Additionally, the association between setting events and more specific environmental events…

  13. Prevalence of Autism Spectrum Phenomenology in Cornelia de Lange and Cri du Chat Syndromes

    Moss, Joanna F.; Oliver, Chris; Berg, Katy; Kaur, Gurmeash; Jephcott, Lesley; Cornish, Kim

    2008-01-01

    Autism spectrum disorder characteristics have not been evaluated in Cornelia de Lange and Cri du Chat syndromes using robust assessments. The Autism Diagnostic Observation Schedule and Social Communication Questionnaire were administered to 34 participants with Cornelia de Lange syndrome and a comparison group of 23 participants with Cri du Chat…

  14. A Boy with a Mild Case of Cornelia de Lange Syndrome with Above Average Intelligence.

    Lacassie, Yves; Bobadilla, Olga; Cambias, Ron D., Jr.

    1997-01-01

    Describes the characteristics of an 11-year-old boy who represents the only documented case of an individual with Cornelia de Lange syndrome who also has above average cognitive functioning. Major diagnostic criteria for de Lange syndrome and comparisons with other severe and mild cases are discussed. (Author/CR)

  15. Blogging in the Target Language: Review of the “Lang-8” Online Community

    Judith Bündgens-Kosten

    2011-06-01

    Full Text Available Progress in language learning can be framed as the development of skills in four domains: reading, speaking, writing, and listening. While material to improve reading and listening skills is fairly easy to find, practicing productive skills outside the formal classroom can be more difficult. This is a review of language learning community, Lang-8 (www.lang-8.com.

  16. Delineating the Profile of Autism Spectrum Disorder Characteristics in Cornelia de Lange and Fragile X Syndromes

    Moss, Joanna; Oliver, Chris; Nelson, Lisa; Richards, Caroline; Hall, Scott

    2013-01-01

    An atypical presentation of autism spectrum disorder is noted in Cornelia de Lange and Fragile X syndromes, but there are few detailed empirical descriptions. Participants in this study were individuals with Cornelia de Lange syndrome (n = 130, M age = 17.19), Fragile X syndrome (n = 182, M age = 16.94), and autism spectrum disorder (n = 142, M…

  17. Soot concentrations along busy inland waterways in the Netherlands; Roetconcentraties langs drukke binnenvaarwegen in Nederland

    Keuken, M.; Jonkers, S.; Moerman, M. [TNO Built Environment and Geosciences, Delft (Netherlands); Hoek, G. [Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht (Netherlands)

    2013-08-15

    Exploratory research by TNO and IRAS shows that residents in the Netherlands are exposed to soot concentrations along busy inland waterways similar to living along a busy highway [Dutch] Verkennend onderzoek van TNO en IRAS laat zien dat bewoners langs drukke binnenvaarwegen worden blootgesteld aan roetconcentraties vergelijkbaar met wonen langs een drukke snelweg.

  18. De Juan Goytisolo à Monique Lange, de Monique Lange à Juan Goytisolo : une "intertextualité conjugale"

    Emmanuel Le Vagueresse

    2006-09-01

    Full Text Available Juan Goytisolo (né en 1931, écrivain espagnol, et Monique Lange (1926-1996, écrivain français, ont produit chacun une œuvre à forte résonance autobiographique, sous couvert de fiction, et qui crée un effet très particulier d’inter­textualité par le simple fait qu’ils étaient, dans la vie, mari et femme... D’où ce titre « d’intertextualité conjugale », car ces récits auto-fictionnels croisés de relations communes s’enri­chissent particulièrement du regard critique et lucide de la romancière sur les obsessions personnelles de son écrivain de mari, les décryptant par le biais de personnages « inventés » qui, non seulement renseignent sur un destin littéraire partagé, mais encore et surtout, dans une configuration rare de double écriture, permettent chez Lange de lire différemment les lignes souvent floues (sur la sexualité, les parias, le monde arabe de l’écrivain espagnol bien connu, et même de démystifier ses discours d’Espagnol marginal.

  19. Geen recht de moed te verliezen. Leven en werken van dr. H.M. de Lange (1919-2001)

    Witte-Rang, M.E.

    2008-01-01

    This study deals with the contribution of the Dutch economist Dr. H.M. de Lange to the ecumenical debate on social-ethics. To this end, the first part gives a description of the work of De Lange. Through the individual De Lange the study provides an insight in the worldwide ecumenical movement and

  20. Jervell and Lange-Nielson Syndrome masquerading as intractable epilepsy

    Jagdish P Goyal

    2012-01-01

    Full Text Available The long QT syndrome (LQTS is a cause of syncope and sudden death. Jervell and Lange-Nielson syndrome (JLNS is an uncommon form of LQTS, having autosomal recessive transmission, and is associated with congenital deafness. We report a case of JLNS in a child who presented to us with refractory epilepsy. The cardiac cause of seizures was suspected as the child was hypotensive and pulseless during the episode of seizures. The child was diagnosed as JLNS based on Schwartz diagnostic criteria for LQTS and congenital sensorineural deafness. The child responded well to β-blocker therapy. Antiepileptic drugs were stopped. The screening of family members with ECG revealed a QT interval more than required for diagnosis of LQTS but they were asymptomatic. All asymptomatic family members were also put on metoprolol. All of them showed great improvement with the reduction of the QT interval on ECG. The patient was doing well on immediate follow-up.

  1. Punaste õhtute purpur / Jüri Annist

    Annist, Jüri, 1950-

    2015-01-01

    Punane tamm, punane vaher, jaapani juudapuulehik, äädikapuu, pihlaka Sorbus sort 'Dodong' ja tiivulise kikkapuu sort 'Compactus' värvuvad sügisel kaunilt punaseks. Autori arvates on kõige punasem sügisvärvus tiivulisel kikkapuul 'Compactus'

  2. Eestlastest tippjuhid kerge südamega võõrsile leiba teenima ei lähe / Mait Raava, Indrek Neivelt, Maive Rute ; interv. Tuuliki Kasonen-Lins

    Raava, Mait

    2006-01-01

    Pro Konsultatsioonide juhtimiskonsultant Mait Raava, Bank Saint Petersburgi nõukogu esimees Indrek Neivelt, Euroopa Komisjoni innovatsiooni ja väikeettevõtluse üksuse direktor Maive Rute vastavad küsimustele, mis puudutavad Eesti juhtide mainet ning töötamist välisriikides

  3. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression.

    Christopher R Shaler

    2017-06-01

    Full Text Available Superantigens (SAgs are potent exotoxins secreted by Staphylococcus aureus and Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a "cytokine storm" with severe and sometimes life-threatening consequences typically encountered in toxic shock syndrome (TSS. Given the rapidity with which TSS develops, designing timely and truly targeted therapies for this syndrome requires identification of key mediators of the cytokine storm's initial wave. Equally important, early host responses to SAgs can be accompanied or followed by a state of immunosuppression, which in turn jeopardizes the host's ability to combat and clear infections. Unlike in mouse models, the mechanisms underlying SAg-associated immunosuppression in humans are ill-defined. In this work, we have identified a population of innate-like T cells, called mucosa-associated invariant T (MAIT cells, as the most powerful source of pro-inflammatory cytokines after exposure to SAgs. We have utilized primary human peripheral blood and hepatic mononuclear cells, mouse MAIT hybridoma lines, HLA-DR4-transgenic mice, MAIThighHLA-DR4+ bone marrow chimeras, and humanized NOD-scid IL-2Rγnull mice to demonstrate for the first time that: i mouse and human MAIT cells are hyperresponsive to SAgs, typified by staphylococcal enterotoxin B (SEB; ii the human MAIT cell response to SEB is rapid and far greater in magnitude than that launched by unfractionated conventional T, invariant natural killer T (iNKT or γδ T cells, and is characterized by production of interferon (IFN-γ, tumor necrosis factor (TNF-α and interleukin (IL-2, but not IL-17A; iii high-affinity MHC class II interaction with SAgs, but not MHC-related protein 1 (MR1 participation, is required for MAIT cell activation; iv MAIT cell responses to SEB can occur in a T cell receptor (TCR Vβ-specific manner but are largely contributed by IL-12 and IL-18; v as MAIT cells are primed by SAgs, they also begin to

  4. Using a {sigma}-coordinate numerical ocean model for simulating the circulation at Ormen Lange

    Eliassen, Inge K.; Berntsen, Jarle

    2000-01-01

    This report describes a numerical model for the simulation of circulation at the Ormen Lange oil field. The model uses a topography following vertical coordinate and time split integration procedure. The model is implemented for a 28 km x 46 km area at Ormen Lange. The equations are given in detail and numerical experiments are discussed. The numerical studies investigate how the flow specified at open boundaries surrounding the Ormen Lange area may be interpolated into the interior domain taking into account the conservation laws that are believed to determine the flow and the local topography.

  5. Successful Growth Hormone Therapy in Cornelia de Lange Syndrome.

    de Graaf, Michael; Kant, Sarina G; Wit, Jan Maarten; Willem Redeker, Egbert Johan; Eduard Santen, Gijs Willem; Henriëtta Verkerk, Annemieke Johanna Maria; Uitterlinden, André Gerardus; Losekoot, Monique; Oostdijk, Wilma

    2017-12-15

    Cornelia de Lange syndrome (CdLS) is a both clinically and genetically heterogeneous syndrome. In its classical form, it is characterised by distinctive facial features, intra-uterine growth retardation, short stature, developmental delay, and anomalies in multiple organ systems. NIPBL, SMC1A, SMC3, RAD21 and HDAC8, all involved in the cohesin pathway, have been identified to cause CdLS. Growth hormone (GH) secretion has been reported as normal, and to our knowledge, there are no reports on the effect of recombinant human GH treatment in CdLS patients. We present a patient born small for gestational age with persistent severe growth retardation [height -3.4 standard deviation score (SDS)] and mild dysmorphic features, who was treated with GH from 4.3 years of age onward and was diagnosed 6 years later with CdLS using whole-exome sequencing. Treatment led to a height gain of 1.6 SDS over 8 years. Treatment was interrupted shortly due to high serum insulin-like growth factor-1 serum values. In conclusion, GH therapy may be effective and safe for short children with CdLS.

  6. Mechanisms and processes of stratal disruption and mixing in the development of m??langes and broken formations: Redefining and classifying m??langes

    Festa, A.; Dilek, Yildirim; Pini, Gian Andrea; Codegone, Giulia; Ogata, K.

    2012-01-01

    The terms m??lange and broken formation have been used in different ways in the literature. The lack of agreement on their definition often leads to confusion and misinterpretations. An evaluation of the various uses of these terms allows us to consider several types of chaotic rock bodies

  7. Plaadid / Mait Eelrand

    Eelrand, Mait, 1950-

    2006-01-01

    Uutest heliplaatidest JJ CAle & Eric Clapton "The Road To escondido", Fergie "The Dutchess", Cosmoskva "Juniper", "The Devil Wears Prada", Peaches "Impeach My Bush", Ludacris "Release Therapy", Milburn "Well Well Well"

  8. Unusual association of non-anaplastic Wilms tumor and Cornelia de Lange syndrome: case report.

    Santoro, Claudia; Apicella, Andrea; Casale, Fiorina; La Manna, Angela; Di Martino, Martina; Di Pinto, Daniela; Indolfi, Cristiana; Perrotta, Silverio

    2016-06-13

    Cornelia de Lange syndrome is the prototype for cohesinopathy disorders, which are characterized by defects in chromosome segregation. Kidney malformations, including nephrogenic rests, are common in Cornelia de Lange syndrome. Only one post-mortem case report has described an association between Wilms tumor and Cornelia de Lange syndrome. Here, we describe the first case of a living child with both diseases. Non-anaplastic triphasic nephroblastoma was diagnosed in a patient carrying a not yet reported mutation in NIPBL (c.4920 G > A). The patient had the typical facial appearance and intellectual disability associated with Cornelia de Lange syndrome in absence of limb involvement. The child's kidneys were examined by ultrasound at 2 years of age to exclude kidney abnormalities associated with the syndrome. She underwent pre-operative chemotherapy and nephrectomy. Seven months later she was healthy and without residual detectable disease. The previous report of such co-occurrence, together with our report and previous reports of nephrogenic rests, led us to wonder if there may be any causal relationship between these two rare entities. The wingless/integrated (Wnt) pathway, which is implicated in kidney development, is constitutively activated in approximately 15-20 % of all non-anaplastic Wilms tumors. Interestingly, the Wnt pathway was recently found to be perturbed in a zebrafish model of Cornelia de Lange syndrome. Mutations in cohesin complex genes and regulators have also been identified in several types of cancers. On the other hand, there is no clear evidence of an increased risk of cancer in Cornelia de Lange syndrome, and no other similar cases have been published since the fist one reported by Cohen, and this prompts to think Wilms tumor and Cornelia de Lange syndrome occurred together in our patient by chance.

  9. Unusual association of non-anaplastic Wilms tumor and Cornelia de Lange syndrome: case report

    Santoro, Claudia; Apicella, Andrea; Casale, Fiorina; La Manna, Angela; Di Martino, Martina; Di Pinto, Daniela; Indolfi, Cristiana; Perrotta, Silverio

    2016-01-01

    Cornelia de Lange syndrome is the prototype for cohesinopathy disorders, which are characterized by defects in chromosome segregation. Kidney malformations, including nephrogenic rests, are common in Cornelia de Lange syndrome. Only one post-mortem case report has described an association between Wilms tumor and Cornelia de Lange syndrome. Here, we describe the first case of a living child with both diseases. Non-anaplastic triphasic nephroblastoma was diagnosed in a patient carrying a not yet reported mutation in NIPBL (c.4920 G > A). The patient had the typical facial appearance and intellectual disability associated with Cornelia de Lange syndrome in absence of limb involvement. The child’s kidneys were examined by ultrasound at 2 years of age to exclude kidney abnormalities associated with the syndrome. She underwent pre-operative chemotherapy and nephrectomy. Seven months later she was healthy and without residual detectable disease. The previous report of such co-occurrence, together with our report and previous reports of nephrogenic rests, led us to wonder if there may be any causal relationship between these two rare entities. The wingless/integrated (Wnt) pathway, which is implicated in kidney development, is constitutively activated in approximately 15–20 % of all non-anaplastic Wilms tumors. Interestingly, the Wnt pathway was recently found to be perturbed in a zebrafish model of Cornelia de Lange syndrome. Mutations in cohesin complex genes and regulators have also been identified in several types of cancers. On the other hand, there is no clear evidence of an increased risk of cancer in Cornelia de Lange syndrome, and no other similar cases have been published since the fist one reported by Cohen, and this prompts to think Wilms tumor and Cornelia de Lange syndrome occurred together in our patient by chance

  10. Mechanisms and processes of stratal disruption and mixing in the development of mélanges and broken formations: Redefining and classifying mélanges

    Festa, A.; Dilek, Y.; Pini, G. A.; Codegone, G.; Ogata, K.

    2012-09-01

    The terms mélange and broken formation have been used in different ways in the literature. The lack of agreement on their definition often leads to confusion and misinterpretations. An evaluation of the various uses of these terms allows us to consider several types of chaotic rock bodies originated by tectonic, sedimentary and diapiric processes in different tectonic settings. Our review of stratal disruption and mixing processes shows that there exists a continuum of deformation structures and processes in the generation of mélanges and broken formations. This continuum is directly controlled by the increase of the degree of consolidation with burial. In tectonically active environments, at the shallow structural levels, the occurrence of poorly consolidated sediments favors gravitational deformation. At deeper structural levels, the deformation related to tectonic forces becomes gradually more significant with depth. Sedimentary (and diapiric) mélanges and broken formations represent the products of punctuated stratal disruption mechanisms recording the instantaneous physical conditions in the geological environment at the time of their formation. The different kinematics, the composition and lithification degree of sediments, the geometry and morphology of the basins, and the mode of failure propagation control the transition between different types of mass-transported chaotic bodies, the style of stratal disruption, and the amount of rock mixing. Tectonically broken formations and mélanges record a continuum of deformation that occurs through time and different degrees of lithification during a progressive increase of the degree of consolidation and of the diagenetic and metamorphic mineral transformation. Systematic documentation of the mechanisms and processes of the formation of different broken formations and mélanges and their interplay in time and space are highly important to increase the understanding of the evolutionary history of accretionary

  11. Repensar la criminología con Luhmann, Lang, Foucault

    Luciano Nuzzo

    2013-01-01

    Full Text Available El tema que el artículo afronta es: ¿cuál es el objeto de la criminología? Para responder a esta pregunta es necesario analizar el estatuto epistemológico delsaber criminológico. Pero si se busca una respuesta a este problema dentro del debate criminológico, se quedará desilusionado. La criminología parece no darse plenamente cuenta de la necesidad de un método capaz de hacer posible una comprensión de su propio objeto. El autor propone seguir tres caminosque, desde perspectivas diferentes, afrontan el problema fundamental para cada observación social, es decir, el hecho de que cada observación de la sociedad es parte de lo que se quiere describir. El primer recorrido propuesto es la teoría de los sistemas sociales de Niklas Luhmann. Mediante la distinción entre observación de primer y de segundo orden es posible comprender el problema del objeto sin caer en la paradoja de la autoimplicación. El segundo recorrido propuesto es una obra de arte y precisamente el film de Frit Lang M., El monstruo de Dusseldorf. El arte, en efecto, permite ver lo que no podemos ver dentro de los confines de una observación científica. El arte permite rodear el punto ciego de la propia observación. Por último, el tercer recorrido propuesto al lector es la genealogía del poder descrita por Michel Foucault en el curso al College de France de 1974-1975, dedicado a los Anormales Estos tres recorridos permiten comprender desde perspectivas diferentes que la criminología no podrá producir conocimientos suficientemente adecuados a su objeto si no comprende cómo ella misma está siempre implicada en la construcción del objeto que observa.

  12. [Cornelia de Lange Syndrome and multiple hormonal deficiency, an unusual association. Clinical case].

    Mora-Bautista, Víctor M; Mendoza-Rojas, Víctor; Contreras-García, Gustavo A

    2017-06-01

    Cornelia de Lange syndrome is a genetic disease characterized by distinctive facial features, failure to thrive, microcephaly and several malformations associated. Its main endocrinological features are anomalies of the genitalia. We present a 13-year-old boy, who suffered from complicated aspiration pneumonia and showed Cornelia de Lange syndrome phenotype, with global developmental delay, suction-swallowing abnormalities, short stature and abnormal genitalia associated. His bone age was delayed, so he underwent full endocrinological panel. Central hypothyroidism, growth hormone deficiency and low luteinizing hormone-follicle-stimulating hormone levels were observed and multiple pituitary hormone deficiencies diagnosis was made. Basal cortisol, adrenocorticotropic hormone and prolactin levels were normal. He received thyroid hormonal substitution. Multiple pituitary hormone deficiencies are an unusual feature of De Lange syndrome. We suggest evaluating all different endocrine axes in these patients. Sociedad Argentina de Pediatría.

  13. Kortlægning af luftkvalitet langs motor- og landeveje i Danmark

    Jensen, Steen Solvang; Im, Ulas; Ketzel, Matthias

    2016-01-01

    Denne artikel beskriver resultaterne af en kortlægning af luftkvaliteten langs motor- og landeveje i hele Danmark. Det er første gang, at der skabes et nationalt datasæt af modellerede luftkvalitetsdata langs hele statsvejnettet. Beregningerne er gennemført for årsmiddelkoncentrationer i 2012 af ...... sundheds-relaterede stoffer NO2, PM2.5 og PM10. Kortlægningen er gennemført med OML-Highway luftkvalitets-modellen, og anvendte metoder og datagrundlag er beskrevet. Endvidere er beregningerne sammenholdt med tidligere gennemførte målinger og beregninger....

  14. Unpredictable drug reaction in a child with Cornelia de Lange syndrome.

    Stevic, Marija; Milojevic, Irina; Bokun, Zlatko; Simic, Dusica

    2015-02-01

    Preoperative use of midazolam sedation is mandatory during induction of anesthesia in noncooperative and hyperactive children to prevent possible obstacles. Unusual drug reactions rarely occur in patients undergoing anesthesia or in intensive care unit. This report describes an unpredictable drug reaction after a routine midazolam premedication in a patient with no history of allergy. There has been no literature data yet to show that midazolam can provoke respiratory problems in patients with Cornelia de Lange Syndrome. In our opinion midazolam should be avoided in patients with Cornelia de Lange Syndrome, which we enforced after first unpredictable reaction.

  15. Psychological Well-Being in Parents of Children with Angelman, Cornelia de Lange and Cri du Chat Syndromes

    Griffith, G. M.; Hastings, R. P.; Oliver, C.; Howlin, P.; Moss, J.; Petty, J.; Tunnicliffe, P.

    2011-01-01

    Background: The current study focuses on mothers and fathers of children with three rare genetic syndromes that are relatively unexplored in terms of family experience: Angelman syndrome, Cornelia de Lange syndrome and Cri du Chat syndrome. Method: Parents of children with Angelman syndrome (n = 15), Cornelia de Lange syndrome (n = 16) and Cri du…

  16. Bloei-inductie bij Chrysant onder lange dag : toepassing van LED-licht technologie

    Ieperen, van W.; Hogewoning, S.W.; Dam, ten E.

    2011-01-01

    Deze publicatie beschrijft een onderzoek naar daglengte verlenging tijdens de korte dag bij chrysant met behoud van bloei door sturing met speciale LED belichting. In klimaatkamerproeven met LEDs (zonder natuurlijk licht) kon bij Chrysant bloemknopaanleg worden geïnduceerd onder een lange dag (LD),

  17. Historical study: Cornelia C. de Lange (1871-1950)--a pioneer in clinical genetics

    de Knecht-van Eekelen, A.; Hennekam, R. C.

    1994-01-01

    The life and work in the field of clinical genetics of one of the most outstanding Dutch pediatricians of the first half of the twentieth century, Cornelia C. de Lange (1871-1950), is described against the background of the development of pediatrics, anthropogenetics, and clinical genetics in the

  18. Herstel van lange termijn effecten van verzuring en vermesting in het droog zandlandschap

    Siepel, H.; Siebel, H.N.; Verstrael, T.; Burg, Van den A.; Vogels, J.

    2009-01-01

    Effectgerichte maatregelen zijn de afgelopen jaren succesvol ingezet tegen de korte termijn effecten van verzuring en vermesting in het droog zandlandschap. De accumulatie van zuur en meststoffen heeft echter ook een effect op lange termijn. Hoe zien deze effecten eruit en hoe kan herstelbeheer

  19. Friedrich Albert Lange on neo-Kantianism, socialist Darwinism, and a psychology without a soul.

    Teo, Thomas

    2002-01-01

    Friedrich Albert Lange was a German philosopher, political theorist, educator, and psychologist who outlined an objective psychology in the 1860s. This article shows how some of the most important worldviews of the nineteenth century (Kantianism, Marxism, and Darwinism) were combined creatively in his thought system. He was crucial in the development of neo-Kantianism and incorporated psycho-physiological research on sensation and perception in order to defend Kant's epistemological idealism. Based on a critique of phrenology and philosophical psychology of his time, Lange developed a program of a psychology without a soul. He suggested that only those phenomena that can be observed and controlled should be studied, that psychology should focus on actions and speech, and that for each psychological event the corresponding physical or physiological processes should be identified. Lange opposed introspection and subjective accounts and promoted experiments and statistics. He also promoted Darwinism for psychology while developing a socialist progressive-democratic reading of Darwin in his social theory. The implications of socialist Darwinism on Lange's conceptualization of race are discussed and his prominence in nineteenth century philosophy and psychology is summarized. Copyright 2002 Wiley Periodicals, Inc.

  20. Musical Me'lange and Lyrical Universalism in the Works of Carlos ...

    The paper, ab initio, accepts that music is a veritable vehicle of globalization ... a musical mélange in which people from various cultures could find something to ... a result of the diverse global elements in his works and the resultant universal ...

  1. Analysis of Intentional Communication in Severely Handicapped Children with Cornelia-de-Lange Syndrome.

    Sarimski, Klaus

    2002-01-01

    Intentional communicative acts were assessed in 13 children (ages 2-8) with Cornelia-de-Lange syndrome with a severe mental disability and compared to children with Down and 5p syndromes. The mean number of intentional communicative acts was significantly lower. Analysis of play behaviors revealed the differences were specific for the…

  2. Self-Injurious Behaviour in Cornelia De Lange Syndrome: 1. Prevalence and Phenomenology

    Oliver, C.; Sloneem, J.; Hall, S.; Arron, K.

    2009-01-01

    Background: Self-injurious behaviour is frequently identified as part of the behavioural phenotype of Cornelia de Lange syndrome (CdLS). We conducted a case-control study of the prevalence and phenomenology of self-injurious behaviour (SIB) in CdLS. Methods: A total of 54 participants with CdLS were compared with 46 individuals who were comparable…

  3. Health and Sleep Problems in Cornelia de Lange Syndrome: A Case Control Study

    Hall, S. S.; Arron, K.; Sloneem, J.; Oliver, C.

    2008-01-01

    Background: Self-injury, sleep problems and health problems are commonly reported in Cornelia de Lange Syndrome (CdLS) but there are no comparisons with appropriately matched participants. The relationship between these areas and comparison to a control group is warranted. Method: 54 individuals with CdLS were compared with 46 participants with…

  4. Self-Injurious Behavior, Self-Restraint, and Compulsive Behaviors in Cornelia de Lange Syndrome.

    Hyman, Philippa; Oliver, Chris; Hall, Scott

    2002-01-01

    Analysis of questionnaires completed by caregivers of 77 individuals with Cornelia de Lange syndrome in the United Kingdom found a significant association between self-injurious behaviors and self-restraint, and those displaying both behaviors displayed significantly more compulsions than did those not exhibiting them. Findings extend the…

  5. Normal Language Skills and Normal Intelligence in a Child with de Lange Syndrome.

    Cameron, Thomas H.; Kelly, Desmond P.

    1988-01-01

    The subject of this case report is a two-year, seven-month-old girl with de Lange syndrome, normal intelligence, and age-appropriate language skills. She demonstrated initial delays in gross motor skills and in receptive and expressive language but responded well to intensive speech and language intervention, as well as to physical therapy.…

  6. A Malay boy with the Cornelia de Lange syndrome: clinical and molecular findings

    Bhuiyan, Z. A.; Zilfalil, B. A.; Hennekam, R. C. M.

    2006-01-01

    The Cornelia de Lange syndrome is a multiple congenital anomaly syndrome characterised by dysmorphic facial features, hirsutism, severe growth and developmental delays, and malformed upper limbs. The prevalence is estimated to be one per 10,000. Recently, several independent groups proved that

  7. Infant Attentional Behaviours as Prognostic Indicators in Cornelia-de-Lange Syndrome

    Sarimski, Klaus

    2007-01-01

    Background: Cornelia-de-Lange syndrome is a rare congenital syndrome with poor social relatedness as one of several characteristics of its behavioural phenotype. Methods: Video observations were collected from seven children in their first year of life and again with age 2-4 years. Data were analysed for distribution of object-related and social…

  8. The Behavioural Phenotype of Cornelia de Lange Syndrome: A Study of 56 Individuals

    Basile, Emanuele; Villa, L.; Selicorni, A.; Molteni, M.

    2007-01-01

    Background: Few studies have investigated functional and behavioural variables of Cornelia de Lange Syndrome (CdLS) in a large sample of individuals. The aim of this study is to provide greater insight into the clinical, behavioural and cognitive characteristics that are associated with CdLS. Methods: In total, 56 individuals with CdLS…

  9. Facial Expression of Affect in Children with Cornelia de Lange Syndrome

    Collis, L.; Moss, J.; Jutley, J.; Cornish, K.; Oliver, C.

    2008-01-01

    Background: Individuals with Cornelia de Lange syndrome (CdLS) have been reported to show comparatively high levels of flat and negative affect but there have been no empirical evaluations. In this study, we use an objective measure of facial expression to compare affect in CdLS with that seen in Cri du Chat syndrome (CDC) and a group of…

  10. Cornelia de Lange syndrome and esophageal stricture in a 9-year-old child

    R. G. Artamonov

    2016-01-01

    Full Text Available Children with rare diseases may be found to have various malformations, including those of the gastrointestinal tract. The authors followed up a 9‑year-old child with Cornelia de Lange syndrome, who was found to have esophageal stricture with the development of gastroesophageal reflux and esophagitis.

  11. Toxicity of phosphor esters: Willy Lange (1900-1976) and Gerda von Krueger (1907-after 1970).

    Petroianu, G A

    2010-10-01

    In 1851 Williamson serendipitously discovered a new and efficient way to produce ethers using ethyl iodide and potassium salts. Based on this new synthetic approach, the Frenchman Philippe de Clermont and the Muscovite Wladimir Moschnin, both élèves of Adolphe Wurtz in his Paris School of Chemistry, achieved the synthesis of the first ester of pyrophosphoric acid (TEPP). de Clermont "tasted" the new compound and although TEPP is a potent cholinesterase inhibitor he failed to recognize its toxicity. Almost a century later, in 1932, Willy Lange (1900-1976) and his graduate student Gerda v. Krueger (1907-after 1970) described the toxicity of organophosphonates. While the classic paper of the two "Uber Ester der Monofluorphosphorsäure." is cited by almost everybody working in the field, little is known about Lange and almost nothing about v. Krueger. This brief communication attempts to shed some light on the life of both.

  12. Science et littérature : mélange des genres

    Lissalde, Claire

    2016-01-01

    Cet article expose les démarches et les enjeux de l’organisation de l’exposition Science/Fiction, voyage au cœur du vivant par l’INSERM. Il souligne également l’innovation proposée par une médiation qui utilise le mélange des genres littéraires et scientifiques pour atteindre son public.

  13. Dental Management of Cornelia de Lange Syndrome: A Rare Case Report

    Sandhu, Meera; Nagpal, Mehak; Gulia, Shweta; Sachdev, Vinod

    2015-01-01

    Cornelia de Lange syndrome (CdLS) is a rare, multiple congenital defect often called as Amsterdam dwarfism. The physical phenotype of CdLS includes low birth body weight, short stature and facio-cranial dysmorphia. The diagnosis of the syndrome is based on clinical grounds as there is no biochemical or chromosomal markers for CDLS that makes its diagnosis more complicated. The purpose of this paper is to present a clinical report of a boy emphasizing the importance of multidisciplinary approa...

  14. Holocene reef building on eastern St. Croix, US Virgin Islands: Lang Bank revisited

    Hubbard, D. K.; Gill, I. P.; Burke, R. B.

    2013-09-01

    New core and seismic data suggest that widespread reef building started on Lang Bank by 8,900 CalBP and was dominated by Acropora palmata for the next three millennia. Accretion rates averaged 5.81 m ky-1, a rate that was sufficient for reefs to keep pace with rising sea level on the bank throughout their history. Seismic data show a deep platform interior that was flooded well in advance of reef building along the elevated rim. As a result, those reefs were buffered from sediment stress by their higher positions and active water flow to the west. A. palmata disappeared from the shallow margin by 6,350 yr ago, and reef building on Lang Bank largely ceased by 5,035 CalBP. The reasons for these dramatic events are unclear. Water depth over the reefs was generally shallower than when they started to build, and sea level was slowing dramatically. The new data described here show that reefs flourished on Lang Bank throughout the hiatus suggested by earlier studies (10-7 kyrs BP), and the ultimate demise of shelf-edge reefs is clearly not associated with either poor water quality or sudden sea-level rise. In addition, accretion rates from eastern St. Croix and throughout the Caribbean were well below the high values (≥10 m ky-1) that have been widely assumed. These data collectively argue against models that require extreme environmental or oceanographic phenomena to drown reefs on Lang Bank where reef building was too fast to be outpaced by Holocene sea-level rise. This also bears on more generalized Caribbean models that depend on the presumed reef history on eastern St. Croix.

  15. Self-Injurious Behaviour in Cornelia De Lange Syndrome: 2. Association with Environmental Events

    Sloneem, J.; Arron, K.; Hall, S. S.; Oliver, C.

    2009-01-01

    Background: Self-injurious behaviour is commonly seen in Cornelia de Lange syndrome (CdLS). However, there has been limited research into the aetiology of self-injury in CdLS and whether environmental factors influence the behaviour. Methods: We observed the self-injury of 27 individuals with CdLS and 17 participants who did not have CdLS matched…

  16. Unraveling the history of complex zoned garnets from the North Motagua Mélange (Guatemala)

    Barickman, M. H.; Martin, C.; Flores, K. E.; Harlow, G. E.; Bonnet, G.

    2016-12-01

    The Guatemala Suture Zone (GSZ) is situated in central Guatemala, between the North American and Caribbean plates. Two serpentinite mélanges straddle the Motagua Fault system: the North Motagua Mélange (NMM) and the South Motagua Mélange (SMM). In this study, chemically zoned garnet grains from four eclogite blocks from the NMM were analyzed by EMPA for major elements and LA-ICP-MS for trace elements to unravel the geological history of the eclogites. These eclogites typically consist of euhedral to subhedral garnets, partly retrogressed omphacite grains, and accessory minerals such as phengite and epidote as inclusions in garnet. EBSD was employed to examine apparent garnet inclusions in garnet. The garnet grains in NMM eclogites display complex chemical zonations: all grains roughly show a spessartine-rich core, an almandine-rich core and/or intermediate zone, and a pyrope and grossular-rich rim. Additionally, crystal resorption can be observed between the different zones, and the pyrope-grossular rim can display oscillatory zoning. Finally, grossular-rich zones (crystallographically syntactic) within garnet are present in all studied samples. REE and spider diagrams do not show any significant difference in the patterns of the different zones within the garnet, or indicating that the chemical environment from which each garnet zone grew was broadly the same. The lack of significant variation in LILE content indicates that a fluid influx during garnet growth is unlikely. Consequently, we interpret that garnet grains grew in a largely closed system; however, the presence of the grossular-rich zones, argues for occasional excursions into conditions when either two garnets crystallized or Ca-rich overgrowths that were largely resorbed prior to subsequent continued garnet growth.

  17. Chromian spinels in highly altered ultramafic rocks from the Sartohay ophiolitic mélange, Xinjiang, NW China

    Qiu, Tian; Zhu, Yongfeng

    2018-06-01

    The Sartohay ophiolitic mélange is located in western Junggar (Xinjiang province, NW China), which is a major component of the core part of the Central Asian Orogenic Belt (CAOB). Chromian spinels in serpentinite, talc schist, carbonate-talc schist and listwaenite in Sartohay ophiolitic mélange retain primary compositions with Cr# of 0.39-0.65, Mg# = 0.48-0.67, and Fe3+# evolution of chromian spinels in highly altered ultramafic rocks from the Sartohay ophiolitic mélange. Chromian spinels in serpentinite and talc schist were rimmed by Cr-magnetite, which was dissolved completely during transformation from serpentinite/talc schist to listwaenite. Chromian spinels were then transformed into Fe2+-rich chromite in shear zones, which characterized by high fluid/rock ratios. This Fe2+-rich chromite and/or chromian spinels could then be transformed into Fe3+-rich chromite in oxidizing conditions at shallow levels.

  18. Localized Failure Promoted by Heterogeneous Stresses in Tectonic Mélanges

    Phillips, N. J.; Rowe, C. D.; Ujiie, K.

    2017-12-01

    Within the shallow (PLC) toolbox developed at the University of Maine, which uses Asymptotic Expansion Homogenization (AEH) over a finite element mesh to determine the instantaneous stress distributions in a multiphase system. We model the shale matrix mélange to be deforming through a modified flow law for viscous creep based on coupled frictional sliding and pressure solution, where at a strain rate of 10-12 s-1 the flow stress is 10 MPa under the temperature (190 ºC) and pressure ( 100 MPa) conditions during deformation, and describe the behaviour of the basaltic blocks using experimentally-derived power law flow laws. The results show that at the strain rates calculated based on plate-rate motion, differential stresses high enough to cause comminution of the basalts ( 300 MPa) correspond strongly to areas around the blocks with basalt derived cataclasites. Within the basalt derived cataclasites, thin zones of ultracataclasite record localized slip. We hypothesize that the heterogeneous stress distributions within subduction mélanges: 1) fractures the strong basalt thereby facilitating weakening through fluid-rock interactions, and 2) promotes localized slip (and occasionally seismicity) within these zones of altered basalt along the margins of strong intact basalt.

  19. Effects of herbicides on Behr's metalmark butterfly, a surrogate species for the endangered butterfly, Lange's metalmark

    Stark, John D.; Chen Xuedong; Johnson, Catherine S.

    2012-01-01

    Lange's metalmark butterfly, Apodemia mormo langei Comstock, is in danger of extinction due to loss of habitat caused by invasive exotic plants which are eliminating its food, naked stem buckwheat. Herbicides are being used to remove invasive weeds from the dunes; however, little is known about the potential effects of herbicides on butterflies. To address this concern we evaluated potential toxic effects of three herbicides on Behr's metalmark, a close relative of Lange's metalmark. First instars were exposed to recommended field rates of triclopyr, sethoxydim, and imazapyr. Life history parameters were recorded after exposure. These herbicides reduced the number of adults that emerged from pupation (24–36%). Each herbicide has a different mode of action. Therefore, we speculate that effects are due to inert ingredients or indirect effects on food plant quality. If these herbicides act the same in A. mormo langei, they may contribute to the decline of this species. - Highlights: ► We evaluated the effects of three herbicides on the butterfly, Behr's metalmark. ► These herbicides are used to control invasive weeds in butterfly habitat. ► The herbicides reduced adult butterfly emergence. - Herbicides are used to remove invasive weeds from butterfly habitat. Certain herbicides may be having a negative effect on butterflies.

  20. Validation of the Eddy Viscosity and Lange Wake Models using Measured Wake Flow Characteristics Behind a Large Wind Turbine Rotor

    Jeon, Sang Hyeon; Kim, Bum Suk; Huh, Jong Chul [Jeju National Univ., Jeju (Korea, Republic of); Go, Young Jun [Hanjin Ind, Co., Ltd., Yangsan (Korea, Republic of)

    2016-01-15

    The wake effects behind wind turbines were investigated by using data from a Met Mast tower and the SCADA (Supervisory Control and Data Acquisition) system for a wind turbine. The results of the wake investigations and predicted values for the velocity deficit based on the eddy viscosity model were compared with the turbulence intensity from the Lange model. As a result, the velocity deficit and turbulence intensity of the wake increased as the free stream wind speed decreased. In addition, the magnitude of the velocity deficit for the center of the wake using the eddy viscosity model was overestimated while the turbulence intensity from the Lange model showed similarities with measured values.

  1. Optimization Analysis on Parameters of Cleaning Sieve of Rape Combine of "Bi Lang 4LZ(Y)-1.0"

    Wu Mingliang; Tang Lun; Guan Chunyun; Tang Chuzhou

    2014-01-01

    Against the phenomenon of high impurity rate and cane and pod shell are difficult to discharge at the end of the sieve for rape combine of "Bi Lang 4LZ(Y)-1.0". This study take cleaning sieve of rape combine of "Bi Lang 4LZ(Y)-1.0" as study object, analyzed the movement of materials on sieve, established the virtual prototype model of the cleaning sieve of this rape combine, taken materials and cleaning sieve all at the best motion state as constraint conditions and optimized the structure an...

  2. Profanum et Promissio : het begrip wereld in de missionaire ecclesiologieën van Hans Hoekendijk, Hans Jochen Margull en Ernst Lange

    Petter, Frank Anthonie

    2002-01-01

    Profanum et Promissio The concept of ‘world’ in the missionary ecclesiologies of Hans Hoekendijk, Hans Jochen Margull and Ernst Lange. This study deals with the concept of ‘world’ in the missionary ecclesiologies of Hans Hoekendijk (1912-1975), Hans Jochen Margull (1925-1982) and Ernst Lange

  3. Kuidas parandada elu Eestis - 1943. a. variant / Sirje Annist

    Annist, Sirje

    2006-01-01

    Artikkel on jätkuks ajakirjas Kultuur ja Elu (1994, nr. 1-2) ilmunud lühitutvustusele "Kahtlaste leitud paberite lugu proloogi ja epiloogiga. Saksa okupatsiooni aegne autonoomiakava". Lisa: Raport poliitilisest kriisist ning selle tagajärgedest Eestis. Lk. 78-88

  4. Päev, mil sa midagi ei ostnud / Aet Annist

    Annist, Aet

    1999-01-01

    Kuus aastat on Kalle Lasni juhitud organisatsiooni Media Foundations, teinud tarbimisvastast reklaami ja kutsunud tähistama 26. nov.-t ostuvaba päevana. Algselt ameerika ostjaskonnale suunatud üleskutse on jõudnud ülejäänud tarbimisühiskondadeni. Ajakirjast 'Ethical Consumerism', mis kogub kirjeldusi Täiesti Mittevajalikest Asjust (TYNKYNS) ning lisab sapiseid soovitusi nende omandajatele

  5. TBT - gehalten en effecten bij de Gewone alikruik, de Gevlochten Fuikhoorn en de Purperslak langs de Nederlandse kust in 2011

    Hoek-van Nieuwenhuizen, van M.; Jol, J.G.

    2011-01-01

    Sinds 2005 analyseert IMARES in opdracht van Rijkswaterstaat het voorkomen van intersex bij de Gewone Alikruiken (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met organotinverbindingen vast te

  6. De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes

    Gil-Rodríguez, María Concepción; Deardorff, Matthew A; Ansari, Morad

    2015-01-01

    Cornelia de Lange syndrome (CdLS) is characterized by facial dysmorphism, growth failure, intellectual disability, limb malformations, and multiple organ involvement. Mutations in five genes, encoding subunits of the cohesin complex (SMC1A, SMC3, RAD21) and its regulators (NIPBL, HDAC8), account ...

  7. De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes

    Gil-Rodriguez, M.C.; Deardorff, M.A.; Ansari, M.; Tan, C.A.; Parenti, I.; Baquero-Montoya, C.; Ousager, L.B.; Puisac, B.; Hernandez-Marcos, M.; Teresa-Rodrigo, M.E.; Marcos-Alcalde, I.; Wesselink, J.J.; Lusa-Bernal, S.; Bijlsma, E.K.; Braunholz, D.; Bueno-Martinez, I.; Clark, D.; Cooper, N.S.; Curry, C.J.; Fisher, R.; Fryer, A.; Ganesh, J.; Gervasini, C.; Gillessen-Kaesbach, G.; Guo, Y.; Hakonarson, H.; Hopkin, R.J.; Kaur, M.; Keating, B.J.; Kibaek, M.; Kinning, E.; Kleefstra, T.; Kline, A.D.; Kuchinskaya, E.; Larizza, L.; Li, Y.R.; Liu, X.; Mariani, M.; Picker, J.D.; Pie, A.; Pozojevic, J.; Queralt, E.; Richer, J.; Roeder, E.; Sinha, A.; Scott, R.H.; So, J.; Wusik, K.A.; Wilson, L.; Zhang, J.; Gomez-Puertas, P.; Casale, C.H.; Strom, L.; Selicorni, A.; Ramos, F.J.; Jackson, L.G.; Krantz, I.D.; Das, S.; Hennekam, R.C.; Kaiser, F.J.; FitzPatrick, D.R.; Pie, J.

    2015-01-01

    Cornelia de Lange syndrome (CdLS) is characterized by facial dysmorphism, growth failure, intellectual disability, limb malformations, and multiple organ involvement. Mutations in five genes, encoding subunits of the cohesin complex (SMC1A, SMC3, RAD21) and its regulators (NIPBL, HDAC8), account for

  8. Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein-Taybi Syndromes

    Crawford, Hayley; Waite, Jane; Oliver, Chris

    2017-01-01

    Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein-Taybi syndromes (RTS), and compared the symptomatology to normative data for…

  9. Simultaneous Analysis of the Behavioural Phenotype, Physical Factors, and Parenting Stress in People with Cornelia De Lange Syndrome

    Wulffaert, J.; van Berckelaer-Onnes, I.; Kroonenberg, P.; Scholte, E.; Bhuiyan, Z.; Hennekam, R.

    2009-01-01

    Background: Studies into the phenotype of rare genetic syndromes largely rely on bivariate analysis. The aim of this study was to describe the phenotype of Cornelia de Lange syndrome (CdLS) in depth by examining a large number of variables with varying measurement levels. Virtually the only suitable multivariate technique for this is categorical…

  10. Effects of Social Context on Social Interaction and Self-Injurious Behavior in Cornelia de Lange Syndrome

    Arron, Kate; Oliver, Chris; Hall, Scott; Sloneem, Jenny; Forman, Debbie; McClintock, Karen

    2006-01-01

    Cornelia de Lange syndrome is reported to be associated with self-injurious behavior (SIB) and social avoidance. We used analog methodology to examine the effect of manipulating adult social contact on social communicative behaviors and SIB in 16 children with this syndrome. For 9 participants engagement behavior was related to levels of adult…

  11. A Longitudinal Follow-Up Study of Affect in Children and Adults with Cornelia de Lange Syndrome

    Nelson, Lisa; Moss, Jo; Oliver, Chris

    2014-01-01

    Studies of individuals with Cornelia de Lange syndrome (CdLS) have described changes in mood and behavior with age, although no empirical or longitudinal studies have been conducted. Caregivers of individuals with CdLS (N = 67), cri du chat syndrome (CdCS; N = 42), and Fragile X syndrome (FXS; N = 142) completed the Mood, Interest and Pleasure…

  12. Social Behavior and Characteristics of Autism Spectrum Disorder in Angelman, Cornelia de Lange, and Cri du Chat Syndromes

    Moss, Joanna; Howlin, Patricia; Hastings, Richard Patrick; Beaumont, Sarah; Griffith, Gemma M.; Petty, Jane; Tunnicliffe, Penny; Yates, Rachel; Villa, Darrelle; Oliver, Chris

    2013-01-01

    We evaluated autism spectrum disorder (ASD) characteristics and social behavior in Angelman (AS; "n" ?=? 19; mean age ?=?10.35 years), Cornelia de Lange (CdLS; "n" ?=? 15; mean age ?=?12.40 years), and Cri du Chat (CdCS, also known as 5 p-syndrome; "n" ?=? 19; mean age ?=? 8.80 years) syndromes. The proportion of…

  13. Carbon Markets and REDD in South-East Asia: An Interview with Chris Lang from REDD-Monitor

    Oliver Pye

    2012-01-01

    Full Text Available Chris Lang is a climate justice activist and currently runs REDD-Monitor, a website that follows projects and developments around REDD (www.redd-monitor.org. The acronym REDD refers to Re- ducing Emissions from Deforestation and Forest Degradation and is a UN programme that aims to offer incentives for countries in the Global South to reduce emissions from deforestation by creating financial values for the forest carbon stocks. In this interview, Lang talks about structural shortcomings of REDD and the danger of carbon cowboys, provides an insight in the 1 billion dollar agreement between Norway and Indonesia, and discusses the relation between REDD and indigenous peoples’ rights. ----- Chris Lang ist Klimaaktivist und betreibt derzeit die Webseite REDD-Monitor, die Projekte und En- twicklungen rund um REDD verfolgt (www.redd-monitor.org. Die Abkürzung REDD bezieht sich auf das UN-Programm Reducing Emissions from Deforestation and Forest Degradation, das darauf abzielt, Anreize für Länder des globalen Südens zu schaffen, ihre Emissionen aus Abholzung durch finanzielle Werte für den Kohlenstoffgehalt der Wälder zu reduzieren. In diesem Interview spricht Lang über strukturelle Schwächen von REDD und der Gefahr durch carbon cowboys. Er gibt einen Einblick in das 1-Milliarde-Dollar Abkommen zwischen Norwegen und Indonesien und diskutiert die Beziehung zwischen REDD und den Rechten indigener Völker.

  14. En rask eller lang og kronglete vei til topps? Næringslivslederes karriereforløp

    Trygve Gulbrandsen

    2018-01-01

    Full Text Available Det er mange studier av den sosiale bakgrunnen til toppledere i næringslivet. Et tema som har fått mindre oppmerksomhet, er hvor lang tid det tok for lederne å nå til topps. En skulle forvente at ledere med bakgrunn fra alminnelige kår brukte lenger tid opp til sine topposisjoner enn kolleger fra de øverste sosiale lag. Analysene i denne artikkelen viser imidlertid at dette ikke stemmer. Toppledere i norsk næringsliv med fedre hjemmehørende i arbeiderklassen trengte ikke flere år på å bli toppledere enn ledere med fedre som tilhørte overklassen. Derimot viser det seg at jo høyere utdanning mor hadde, desto raskere karriere hadde topplederne.

  15. A mélange of subduction temperatures: Evidence from Zr-in-rutile thermometry for strengthening of the subduction interface

    Penniston-Dorland, Sarah C.; Kohn, Matthew J.; Piccoli, Philip M.

    2018-01-01

    The Catalina Schist contains a spectacular, km-scale amphibolite facies mélange zone, thought to be part of a Cretaceous convergent margin plate interface. In this setting, blocks ranging from centimeters up to ≥100 m in diameter are surrounded by finer-grained matrix that is derived from the blocks. Blocks throughout the mélange represent a diversity of protoliths derived from basalts, cherts and other sediments, and hydrated mantle, but all contain assemblages consistent with upper amphibolite-facies conditions, suggesting a relatively restricted range of depths and temperatures over which material within the mélange was metamorphosed. This apparent uniformity of metamorphic grade contrasts with other mélanges, such as the Franciscan Complex, where coexisting rocks with highly variable peak metamorphic grade suggest extensive mixing of materials along the subduction interface. This mixing has been ascribed to flow of material within relatively low viscosity matrix. The Zr content of rutile in samples from across the amphibolite facies mélange of the Catalina Schist was measured to determine peak metamorphic temperatures, identify whether these temperatures were different among blocks, and whether the spatial distribution of temperatures throughout the mélange was systematic or random. Resolvably different Zr contents, between 290 and 720 (±10-40) ppm, are found among the blocks, corresponding to different peak metamorphic temperatures of 650 to 730 (±2-16) °C at an assumed pressure of 1 GPa. These results are broadly consistent with previous thermobarometric estimates. No systematic distribution of temperatures was found, however. Like other mélange zones, material flow within the Catalina Schist mélange was likely chaotic, but appears to have occurred on a more restricted scale compared to some other localities. Progressive metamorphism of mélange matrix is expected to produce rheologically stiffer matrix minerals (such as amphiboles and pyroxenes

  16. Age and microfacies of oceanic Upper Triassic radiolarite components from the Middle Jurassic ophiolitic mélange in the Zlatibor Mountains (Inner Dinarides, Serbia and their provenance

    Gawlick Hans-Jürgen

    2017-08-01

    Full Text Available Oceanic radiolarite components from the Middle Jurassic ophiolitic mélange between Trnava and Rožanstvo in the Zlatibor Mountains (Dinaridic Ophiolite Belt west of the Drina–Ivanjica unit yield Late Triassic radiolarian ages. The microfacies characteristics of the radiolarites show pure ribbon radiolarites without crinoids or thin-shelled bivalves. Beside their age and the preservation of the radiolarians this points to a deposition of the radiolarites on top of the oceanic crust of the Neo-Tethys, which started to open in the Late Anisian. South of the study area the ophiolitic mélange (Gostilje–Ljubiš–Visoka–Radoševo mélange contains a mixture of blocks of 1 oceanic crust, 2 Middle and Upper Triassic ribbon radiolarites, and 3 open marine limestones from the continental slope. On the basis of this composition we can conclude that the Upper Triassic radiolarite clasts derive either from 1 the younger parts of the sedimentary succession above the oceanic crust near the continental slope or, more convincingly 2 the sedimentary cover of ophiolites in a higher nappe position, because Upper Triassic ribbon radiolarites are only expected in more distal oceanic areas. The ophiolitic mélange in the study area overlies different carbonate blocks of an underlying carbonate-clastic mélange (Sirogojno mélange. We date and describe three localities with different Upper Triassic radiolarite clasts in a mélange, which occurs A on top of Upper Triassic fore-reef to reefal limestones (Dachstein reef, B between an Upper Triassic reefal limestone block and a Lower Carnian reef limestone (Wetterstein reef, and C in fissures of an Upper Triassic lagoonal to back-reef limestone (Dachstein lagoon. The sedimentary features point to a sedimentary and not to a tectonic emplacement of the ophiolitic mélange (= sedimentary mélange filling the rough topography of the topmost carbonate-clastic mélange below. The block spectrum of the underlying and

  17. Age and microfacies of oceanic Upper Triassic radiolarite components from the Middle Jurassic ophiolitic mélange in the Zlatibor Mountains (Inner Dinarides, Serbia) and their provenance

    Gawlick, Hans-Jürgen; Djerić, Nevenka; Missoni, Sigrid; Bragin, Nikita Yu.; Lein, Richard; Sudar, Milan; Jovanović, Divna

    2017-08-01

    Oceanic radiolarite components from the Middle Jurassic ophiolitic mélange between Trnava and Rožanstvo in the Zlatibor Mountains (Dinaridic Ophiolite Belt) west of the Drina-Ivanjica unit yield Late Triassic radiolarian ages. The microfacies characteristics of the radiolarites show pure ribbon radiolarites without crinoids or thin-shelled bivalves. Beside their age and the preservation of the radiolarians this points to a deposition of the radiolarites on top of the oceanic crust of the Neo-Tethys, which started to open in the Late Anisian. South of the study area the ophiolitic mélange (Gostilje-Ljubiš-Visoka-Radoševo mélange) contains a mixture of blocks of 1) oceanic crust, 2) Middle and Upper Triassic ribbon radiolarites, and 3) open marine limestones from the continental slope. On the basis of this composition we can conclude that the Upper Triassic radiolarite clasts derive either from 1) the younger parts of the sedimentary succession above the oceanic crust near the continental slope or, more convincingly 2) the sedimentary cover of ophiolites in a higher nappe position, because Upper Triassic ribbon radiolarites are only expected in more distal oceanic areas. The ophiolitic mélange in the study area overlies different carbonate blocks of an underlying carbonate-clastic mélange (Sirogojno mélange). We date and describe three localities with different Upper Triassic radiolarite clasts in a mélange, which occurs A) on top of Upper Triassic fore-reef to reefal limestones (Dachstein reef), B) between an Upper Triassic reefal limestone block and a Lower Carnian reef limestone (Wetterstein reef), and C) in fissures of an Upper Triassic lagoonal to back-reef limestone (Dachstein lagoon). The sedimentary features point to a sedimentary and not to a tectonic emplacement of the ophiolitic mélange (= sedimentary mélange) filling the rough topography of the topmost carbonate-clastic mélange below. The block spectrum of the underlying and slightly older

  18. Zwischen Aufbegehren und bürgerlicher Rolle: die Lebensgemeinschaft von Helene Lange und Gertrud Bäumer The partnership of Helene Lange und Gertrud Bäumer: a both rebellious and domestic way of life

    Mechthilde Vahsen

    2001-07-01

    Full Text Available Die Forschungsarbeiten analysieren private weibliche Beziehungsformen und ihre Bedeutung für die erste deutsche Frauenbewegung. Im Zentrum der Betrachtung steht eines der wichtigsten Führungspaare dieser Zeit: Helene Lange und Gertrud Bäumer. Die Dissertation von Göttert liefert einen wichtigen Beitrag zur Netzwerkforschung, Schaser beschäftigt sich in ihrer innovativen Studie mit der Lebensgemeinschaft der beiden Frauen, die sie in die frauenbewegten und politischen Kontexte einordnet.These studies analyse the private aspects of female relationship and their significance for the first wave of the German women’s movement. The focus is on the leading couple at that particular time: Helene Lange and Gertrud Bäumer. The dissertation by Göttert contributes an important piece to the network research, whereas Schaser describes in her innovative study the partnership of the two women, which is strongly related to the feminist and political context.

  19. Rein Lang: Eesti kõige väärtuslikum ressurss on mõistus / Rein Lang ; interv. Peep Lillemägi ; komment. Siim Kallas, Jüri Pihl, Väino Linde

    Lang, Rein, 1957-

    2009-01-01

    Justiitsminister Rein Lang vastab küsimustele, mis puudutavad Ameerika Ühendriike kui vabaduse kantsi, ettevõtlusvabadust Ameerika Ühendriikides ja Eestis, tööd justiitsministrina, varasemat karjääri, Eesti põhiseaduse loomist, Euroopa Liidu aluslepingu välja töötamist, avaliku võimu rolli tänapäeva maailmas ning Eesti jõudmist Euroopa rikkamate riikide hulka

  20. NOAA TIFF Image - Backscatter - Lang Bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83

    National Oceanic and Atmospheric Administration, Department of Commerce — This geotiff represents a 1 meter resolution backscatter mosaic of the reef shelf and the steep slopes of the Lang Bank (H12639) of St. Croix, US Virgin Islands. The...

  1. TBT-gehalten en effecten bij de Gewone Alikruik (Littorina littorea) en de Gevlochten Fuikhoorn (Nassarius reticulatus) langs de Nederlandse kust in 2009

    Kaag, N.H.B.M.; Jol, J.; Hoek-van Nieuwenhuizen, van M.

    2009-01-01

    Sinds 2005 analyseert IMARES het voorkomen van intersex bij Gewone Alikruiken (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met TBT vast te stellen.

  2. Zgaga, P., Teichler, U., & Brennan, J. (Eds.) (2012). The globalisation challenge for European higher education / Convergence and Diversity, Centres and Peripheries. Frankfurt/M.: Peter Lang. [Book review

    Strajn, Darko

    2013-01-01

    Book review of: Zgaga, P., Teichler, U., & Brennan, J. (Eds.) (2012). The globalisation challenge for European higher education / Convergence and Diversity, Centres and Peripheries. Frankfurt/M.: Peter Lang. 389 pp., ISBN 978-3-631- 6398-5.

  3. Efficiency of the application of an increasing hydrogel dose in bispore mushrooms cultivation. Agaricus bisporus (Lange Sing. Imbach

    Grzegorz Koc

    2011-01-01

    Full Text Available The economical efficiency of the application of an increasing hydrogel dose in bispore mushrooms (Agaricus bisporus (Lange Sing. Imbach SYLVAN 737 has been experimented in controlled weather conditions. It was found that the application of a 50 and 150 g•m-2 hydrogel dose is not economically proved due to the lack of harvest significant increase. In the cultivation of this particular variety of mushrooms, the optimal hydrogel dose should not be 100 g•m-2 of subsoil.

  4. Scanning Electron Microscope Studies of Interactions between Agaricus bisporus (Lang) Sing Hyphae and Bacteria in Casing Soil

    Masaphy, Segula; Levanon, D.; Tchelet, R.; Henis, Y.

    1987-01-01

    Relationships between the hyphae of Agaricus bisporus (Lang) Sing and bacteria from the mushroom bed casing layer were examined with a scanning electron microscope. Hyphae growing in the casing layer differed morphologically from compost-grown hyphae. Whereas the compost contained thin single hyphae surrounded by calcium oxalate crystals, the casing layer contained mainly wide hyphae or mycelial strands without crystals. The bacterial population in the hyphal environment consisted of several ...

  5. Case Report: Atypical Cornelia de Lange Syndrome [version 2; referees: 1 approved, 2 approved with reservations

    Vito Leanza

    2015-05-01

    Full Text Available Cornelia de Lange Syndrome (CdLS (also called Bushy Syndrome or Amsterdam dwarfism, is a genetic disorder that can lead to several alterations. This disease affects both physical and neuropsychiatric development. The various abnormalities include facial dysmorphia (arched eyebrows, synophrys, depressed nasal bridge, long philtrum, down-turned angles of the mouth, upper-extremity malformations, hirsutism, cardiac defects, and gastrointestinal alterations. The prevalence of this syndrome is approximately one per 15,000. Ultrasound is not the perfect means to diagnose CdLS, however, many abnormalities can be detected prenatally by scrupulous image observation. We report an atypical CdLS case characterized by increased nuchal translucency in the first trimester, normal karyotype, saddle nose, micrognathia with receding jaw, low set ears, facies senilis, arthrogryposis of the hands, absence of the Aranzio ductus venous, dilatation of gallbladder and bowel, a unique umbilical artery, increased volume of amniotic fluid, and intrauterine growth retardation ending with the interruption of pregnancy.

  6. Forest Islands and Castaway Communities: REDD+ and Forest Restoration in Prey Lang Forest

    Courtney Work

    2017-02-01

    Full Text Available Climate Change policies are playing an ever-increasing role in global development strategies and their implementation gives rise to often-unforeseen social conflicts and environmental degradations. A landscape approach to analyzing forest-based Climate Change Mitigation policies (CCM and land grabs in the Prey Lang Forest landscape, Cambodia revealed two Korea-Cambodia partnership projects designed to increase forest cover that are juxtaposed in this paper. Case study data revealed a REDD+ project with little negative impact or social conflict in the project area and an Afforestation/Reforestation (A/R project that created both social and ecological conflicts. The study concludes that forest-based CCM policies can reduce conflict through efforts at minimal transformation of local livelihoods, maximal attention to the tenure rights, responsibilities, and authority of citizens, and by improving, not degrading, the project landscapes. The paper presents the circumstances under which these guidelines are sidestepped by the A/R project, and importantly reveals that dramatic forest and livelihood transformation had already affected the community and environment in the REDD+ project site. There are deep contradictions at the heart of climate change policies toward which attention must be given, lest we leave our future generations with nothing but forest islands and castaway communities.

  7. Characterization of single spore isolates of Agaricus bisporus (Lange) Imbach using conventional and molecular methods.

    Sharma, Manju; Suman, B C; Gupta, Dharmesh

    2014-10-01

    Strains A-15, S11, S-140, and U3 of Agaricus bisporus (Lange) Imbach, were used as parent strains for raising single spore homokaryotic isolates. Out of total 1,642 single spore isolates, only 36 single spore isolates were homokaryons and exhibited slow mycelial growth rate (≤2.0 mm/day) and appressed colony morphology. All these SSIs failed to produce pinheads in Petri plates even after 65 days of incubation, whereas the strandy slow growing SSIs along with parent strains were able to form the fructification in petriplates after 30 days. Out of 24, six ISSR primers, exhibited scorable bands. In the ISSR fingerprints, single spore isolates, homokaryons, lacked amplification products at multiple loci; they grow slowly and all of them had appressed types of colony morphology. The study revealed losses of ISSR polymorphic patterns in non-fertile homokaryotic single spore isolates compared to the parental control or fertile heterokaryotic single spore isolates.

  8. Who Wants to Save the Forest? Characterizing Community-Led Monitoring in Prey Lang, Cambodia

    Turreira-García, Nerea; Meilby, Henrik; Brofeldt, Søren; Argyriou, Dimitris; Theilade, Ida

    2018-06-01

    Community monitoring is believed to be successful only where there is sustained funding, legislation for communities to enforce rules, clear tenure rights, and an enabling environment created by the state. Against this backdrop, we present the case of an autonomous grassroots-monitoring network that took the initiative to protect their forest, in a context, where no external incentives and rule enforcement power were provided. The aim was to analyze the socio-demographic and economic backgrounds, motivations and achievements of forest monitors, compared to non-monitors in the same communities. A total of 137 interviews were conducted in four villages bordering Prey Lang forest in Cambodia. We used binary logit models to identify the factors that influenced the likelihood of being a monitor. Results show that there were few (22%, n = 30) active monitors. Active monitors were intrinsically motivated forest-users, and not specifically associated with a particular gender, ethnicity, or residence-time in that area. The most common interventions were with illegal loggers, and the monitors had a general feeling of success in stopping the illegal activities. Most (73%, n = 22) of them had been threatened by higher authorities and loggers. Our results show that despite the lack of power to enforce rules, absence of external funding and land-ownership rights, and enduring threats of violence and conflicts, autonomous community monitoring may take place when community members are sufficiently motivated by the risk of losing their resources.

  9. Connected Gene Communities Underlie Transcriptional Changes in Cornelia de Lange Syndrome.

    Boudaoud, Imène; Fournier, Éric; Baguette, Audrey; Vallée, Maxime; Lamaze, Fabien C; Droit, Arnaud; Bilodeau, Steve

    2017-09-01

    Cornelia de Lange syndrome (CdLS) is a complex multisystem developmental disorder caused by mutations in cohesin subunits and regulators. While its precise molecular mechanisms are not well defined, they point toward a global deregulation of the transcriptional gene expression program. Cohesin is associated with the boundaries of chromosome domains and with enhancer and promoter regions connecting the three-dimensional genome organization with transcriptional regulation. Here, we show that connected gene communities, structures emerging from the interactions of noncoding regulatory elements and genes in the three-dimensional chromosomal space, provide a molecular explanation for the pathoetiology of CdLS associated with mutations in the cohesin-loading factor NIPBL and the cohesin subunit SMC1A NIPBL and cohesin are important constituents of connected gene communities that are centrally positioned at noncoding regulatory elements. Accordingly, genes deregulated in CdLS are positioned within reach of NIPBL- and cohesin-occupied regions through promoter-promoter interactions. Our findings suggest a dynamic model where NIPBL loads cohesin to connect genes in communities, offering an explanation for the gene expression deregulation in the CdLS. Copyright © 2017 by the Genetics Society of America.

  10. Cochlear implantation in children with Jervell and Lange-Nielsen syndrome - a cautionary tale.

    Broomfield, Stephen J; Bruce, Iain A; Henderson, Lise; Ramsden, Richard T; Green, Kevin M J

    2012-08-01

    Jervell and Lange-Nielsen (JLN) syndrome is a rare cause of congenital profound hearing loss associated with a prolonged QT interval on the electrocardiogram. Children presenting for cochlear implantation with this condition may be asymptomatic but are at risk of sudden death. SCREENING AND SUBSEQUENT: careful management is therefore required to ensure a successful outcome. We present our experience of cochlear implantation in children with JLN syndrome, including two who died unexpectedly, and suggest a protocol for management of such cases. Clinical presentation Four cases of cochlear implantation in JLN syndrome are described. None had any previous cardiological family history. Two were diagnosed pre-operatively but, despite appropriate management under a cardiologist, died from cardiac arrest; the first in the perioperative period following reimplantation for infection, and the second unrelated to his cochlear implant surgery. The other two patients were diagnosed only subsequent to their implantation and continue to use their implants successfully. These cases highlight the variation in presentation of JLN syndrome, and the spectrum of disease severity that exists. Our protocol stresses the importance of careful assessment and counselling of parents by an experienced implant team.

  11. Cornelia de Lange Syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts.

    Pistocchi, A; Fazio, G; Cereda, A; Ferrari, L; Bettini, L R; Messina, G; Cotelli, F; Biondi, A; Selicorni, A; Massa, V

    2013-10-17

    Cornelia de Lange Syndrome is a severe genetic disorder characterized by malformations affecting multiple systems, with a common feature of severe mental retardation. Genetic variants within four genes (NIPBL (Nipped-B-like), SMC1A, SMC3, and HDAC8) are believed to be responsible for the majority of cases; all these genes encode proteins that are part of the 'cohesin complex'. Cohesins exhibit two temporally separated major roles in cells: one controlling the cell cycle and the other involved in regulating the gene expression. The present study focuses on the role of the zebrafish nipblb paralog during neural development, examining its expression in the central nervous system, and analyzing the consequences of nipblb loss of function. Neural development was impaired by the knockdown of nipblb in zebrafish. nipblb-loss-of-function embryos presented with increased apoptosis in the developing neural tissues, downregulation of canonical Wnt pathway genes, and subsequent decreased Cyclin D1 (Ccnd1) levels. Importantly, the same pattern of canonical WNT pathway and CCND1 downregulation was observed in NIPBL-mutated patient-specific fibroblasts. Finally, chemical activation of the pathway in nipblb-loss-of-function embryos rescued the adverse phenotype and restored the physiological levels of cell death.

  12. Executive functioning in Cornelia de Lange syndrome: domain asynchrony and age-related performance.

    Reid, Donna; Moss, Jo; Nelson, Lisa; Groves, Laura; Oliver, Chris

    2017-08-15

    The aim of this study was to examine executive functioning in adolescents and adults with Cornelia de Lange syndrome (CdLS) to identify a syndrome and age-related profile of cognitive impairment. Participants were 24 individuals with CdLS aged 13-42 years (M = 22; SD = 8.98), and a comparable contrast group of 21 individuals with Down syndrome (DS) aged 15-33 years (M = 24; SD = 5.82). Measures were selected to test verbal and visual fluency, inhibition, perseverance/flexibility, and working memory and comprised both questionnaire and performance tests. Individuals with CdLS showed significantly greater impairment on tasks requiring flexibility and inhibition (rule switch) and on forwards span capacity. These impairments were also reported in the parent/carer-rated questionnaire measures. Backwards Digit Span was significantly negatively correlated with chronological age in CdLS, indicating increased deficits with age. This was not identified in individuals with DS. The relative deficits in executive functioning task performance are important in understanding the behavioural phenotype of CdLS. Prospective longitudinal follow-up is required to examine further the changes in executive functioning with age and if these map onto observed changes in behaviour in CdLS. Links with recent research indicating heightened responses to oxidative stress in CdLS may also be important.

  13. Discovery of the early Jurassic Gajia mélange in the Bangong-Nujiang suture zone: Southward subduction of the Bangong-Nujiang Ocean?

    Lai, Wen; Hu, Xiumian; Zhu, Dicheng; An, Wei; Ma, Anlin

    2017-06-01

    lange records a series of geological processes associated with oceanic subduction and continental collision. This paper reports for the first time the presence of Early Jurassic mélange from NW Nagqu in the southern margin of the Bangong-Nujiang suture zone, termed as the Gajia mélange. It shows typically blocks-in-matrix structure with matrix of black shale and siliceous mudstone, and several centimeters to several meters sized blocks of sandstone, silicalite, limestone and basalt. The sandstone blocks consist of homologous sandstone and two types of exotic sandstone, with different modal compositions. The Group 1 of exotic sandstone blocks consists of mainly of feldspar and quartz, whereas the Group 2 is rich in volcanic detritus. The Group 3 of homologous sandstone blocks is rich in feldspar and volcanic detritus with rare occurrence of quartz. U-Pb age data and in situ Hf isotopic compositions of detrital zircons from sandstone blocks are similar to those from the Lhasa terrane, suggesting that the sandstone blocks in the Gajia mélange most probably came from the Lhasa terrane. The YC1σ(2+) age of homologous sandstone blocks is 177 ± 2.4 Ma, suggesting an Early Jurassic depositional age for the sandstones within the Gajia mélange. The Gajia mélange likely records the southward subduction of the Bangong-Nujiang Ocean during the Early Jurassic.

  14. Scaly fabrics and veins of the Mugi and Makimine mélanges in the Shimanto belt, SW Japan

    Ramirez, G. E.; Fisher, D. M.; Yamaguchi, A.; Kimura, G.

    2016-12-01

    Two regionally extensive ancient subduction fault zones provide a microstructural record of the plate boundary deformation associated with underthrusting. These rocks exhibit many of the characteristics associated with exposed ancient subduction fault zones worldwide, including: (1) σ1 is near orthogonal to the deformation fabric (2) there are microstructurally pervasive quartz and calcite filled veins concentrated in coarser blocks and along extensional jogs on slip surfaces, (3) evidence for local diffusion of silica sourced from web-like arrays of slip surfaces (i.e., scaly fabrics), and (4) evidence for cycles of cracking and sealing that record cyclic variations in stress. We present new backscatter SEM observations of scaly fabrics from two ancient subduction-related shear zones from the Shimanto Belt in Japan that exemplify these characteristics and represent the full temperature range of the seismogenic zone: 1) the Mugi mélange (lower ( 130-150 °C) and upper ( 170-200 °C) sections) and 2) Makimine mélange (peak temperatures of 340 °C). The Mugi mélange is an underplated duplex consisting of two horses separated by an OOST. The upper section is bounded at the top by a pseudotachylite-bearing paleodécollement. The Makimine mélange was underplated at the downdip limit of the seismogenic zone. The scaly fabrics associated with these shear zones display significantly different microstructural characteristics. A slip surface from along the upper Mugi is characterized by broader ( 20-30 μm), zones of quartz-poor, anastomosing shear zones composed of fine-grained (0.5-2 μm in length) phyllosilicates. The Makimine mélange exhibits thinner (10-20 μm), anastomosing shear zones with coarser (1-4 μm in length) phyllosilicate grains that are more strongly oriented into parallelism with slip surfaces. Quartz veins are pervasively developed in more competent blocks and are oriented at near perpendicular angles to the slip surfaces. Microstructural analyses

  15. Interpretation of tracer tests performed in fractured rock of the Lange Bramke basin, Germany

    Maloszewski, Piotr; Herrmann, Andreas; Zuber, Andrzej

    Two multitracer tests performed in one of the major cross-fault zones of the Lange Bramke basin (Harz Mountains, Germany) confirm the dominant role of the fault zone in groundwater flow and solute transport. Tracers having different coefficients of molecular diffusion (deuterium, bromide, uranine, and eosine) yielded breakthrough curves that can only be explained by a model that couples the advective-dispersive transport in the fractures with the molecular diffusion exchange in the matrix. For the scale of the tests (maximum distance of 225m), an approximation was used in which the influence of adjacent fractures is neglected. That model yielded nearly the same rock and transport parameters for each tracer, which means that the single-fracture approximation is acceptable and that matrix diffusion plays an important role. The hydraulic conductivity of the fault zone obtained from the tracer tests is about 1.5×10-2m/s, whereas the regional hydraulic conductivity of the fractured rock mass is about 3×10-7m/s, as estimated from the tritium age and the matrix porosity of about 2%. These values show that the hydraulic conductivity along the fault is several orders of magnitude larger than that of the remaining fractured part of the aquifer, which confirms the dominant role of the fault zones as collectors of water and conductors of fast flow. Résumé Deux multitraçages ont été réalisés dans l'une des zones principales de failles du bassin de Lange Bramke (massif du Harz, Allemagne); les résultats confirment le rôle prédominant de la zone de failles pour l'écoulement souterrain et le transport de soluté. Les traceurs, possédant des coefficients de diffusion différents (deutérium, bromure, uranine et éosine), ont fourni des courbes de restitution qui ne peuvent être expliquées que par un modèle qui associe un transport advectif-dispersif dans les fractures à un échange par diffusion moléculaire dans la matrice. A l'échelle des expériences (distance

  16. Kinematic analysis of mélange fabrics: examples and applications from the McHugh Complex, Kenai Peninsula, Alaska

    Kusky, Timothy M.; Bradley, Dwight C.

    1999-12-01

    Permian to Cretaceous mélange of the McHugh Complex on the Kenai Peninsula, south-central Alaska includes blocks and belts of graywacke, argillite, limestone, chert, basalt, gabbro, and ultramafic rocks, intruded by a variety of igneous rocks. An oceanic plate stratigraphy is repeated hundreds of times across the map area, but most structures at the outcrop scale extend lithological layering. Strong rheological units occur as blocks within a matrix that flowed around the competent blocks during deformation, forming broken formation and mélange. Deformation was noncoaxial, and disruption of primary layering was a consequence of general strain driven by plate convergence in a relatively narrow zone between the overriding accretionary wedge and the downgoing, generally thinly sedimented oceanic plate. Soft-sediment deformation processes do not appear to have played a major role in the formation of the mélange. A model for deformation at the toe of the wedge is proposed in which layers oriented at low angles to σ1 are contracted in both the brittle and ductile regimes, layers at 30-45° to σ1 are extended in the brittle regime and contracted in the ductile regime, and layers at angles greater than 45° to σ1 are extended in both the brittle and ductile regimes. Imbrication in thrust duplexes occurs at deeper levels within the wedge. Many structures within mélange of the McHugh Complex are asymmetric and record kinematic information consistent with the inferred structural setting in an accretionary wedge. A displacement field for the McHugh Complex on the lower Kenai Peninsula includes three belts: an inboard belt of Late Triassic rocks records west-to-east-directed slip of hanging walls, a central belt of predominantly Early Jurassic rocks records north-south directed displacements, and Early Cretaceous rocks in an outboard belt preserve southwest-northeast directed slip vectors. Although precise ages of accretion are unknown, slip directions are compatible with

  17. Aqueous Solubility of Hydrocarbon Mixtures Solubilité dans l'eau de mélanges d'hydrocarbures

    De Hemptinne J. C.

    2006-12-01

    Full Text Available The solubility of hydrocarbon components in water is of great importance for the environmental sciences. Its prediction is usually based on using the pure component solubilities and the mole fraction of the components in the mixture. While the pure component solubilities are generally well known, few data exist on the solubility of mixtures. Using a simple relationship leads to an underestimation of the true solubility. This paper presents some new data on the aqueous solubility of binary hydrocarbon mixtures. Using a rigorous thermodynamic analysis, we explain the observed behavior, as well as other data from the literature, including the solubility of jet fuel mixtures in water. The activity coefficient models used for this purpose are NRTL, UNIQUAC and UNIFAC. Considering the small concentration in oil of some very soluble substances, the activity coefficient can become significant and thus explain the fact that solubilities of some component may be as much as twice as large as expected. La solubilité de composés hydrocarbonés dans l'eau est d'une importance cruciale pour les sciences environnementales. Sa prévision est généralement basée sur la solubilité des constituants purs et de leur fraction molaire en mélange. La solubilité des composés purs est généralement bien connue, mais peu de données ont été publiées concernant les mélanges. L'utilisation d'une relation simple conduit à une sous-estimation de la solubilité réelle. Cet article présente quelques données nouvelles de solubilités de mélanges hydrocarbonés simples. Une analyse thermodynamique rigoureuse permet de décrire la solubilité observée, aussi bien pour des mélanges modèles que pour des kérosènes. Les modèles de coefficient d'activité utilisés dans ce but sont NRTL, UNIQUAC et UNIFAC. Étant donné la faible concentration de certains constituants dans l'huile, leurs coefficients d'activité peut devenir important. Ceci explique une

  18. Scanning Electron Microscope Studies of Interactions between Agaricus bisporus (Lang) Sing Hyphae and Bacteria in Casing Soil

    Masaphy, Segula; Levanon, D.; Tchelet, R.; Henis, Y.

    1987-01-01

    Relationships between the hyphae of Agaricus bisporus (Lang) Sing and bacteria from the mushroom bed casing layer were examined with a scanning electron microscope. Hyphae growing in the casing layer differed morphologically from compost-grown hyphae. Whereas the compost contained thin single hyphae surrounded by calcium oxalate crystals, the casing layer contained mainly wide hyphae or mycelial strands without crystals. The bacterial population in the hyphal environment consisted of several types, some attached to the hyphae with filamentlike structures. This attachment may be important in stimulation of pinhead initiation. Images PMID:16347340

  19. El cine de Fritz Lang. Influencia de los mitos y arquetipos en su filmografía

    LÓPEZ HERREROS, ANDRÉS

    2013-01-01

    El siguiente proyecto presenta un estudio personalizado de la obra cinematográfica del cineasta austríaco Fritz Lang para analizar sus tendencias y vincular los arquetipos a sus películas, principalmente las ideas planteadas por los psicólogos Segmund Freud y Carl Gustav Jung referente a las ideas primarias y secundarias. Para ello se muestra la influencia de la mitología en su narrativa cinematográfica, la presencia de arquetipos y elementos propios del subconsciente colectivo en su cine así...

  20. On-line valve monitoring at the Ormen Lange gas plant

    Greenlees, R.; Hale, S. [Score Atlanta Inc., Kennesaw, Georgia (United States)

    2011-07-01

    The purpose of this presentation is to discuss replacing time and labor intensive nuclear outage activities with on line condition monitoring solutions, primarily the periodic verification of MOV functionality discussed in USNRC Generic Letter 96.05. This regulation requires that MOV age related performance degradations are properly identified and accounted for, causing utilities to have to retest valves periodically for the duration of the plants operating license. AECL designed CANDU reactors have a world class performance and safety record, with typical average annual capacity factors of 90%. The CANDU reactor design has the ability to refuel on line, as a result (a) it can be a challenge scheduling all required valve testing into limited duration outage work windows, (b) at multi unit sites, Unit 0 valves can be difficult to test because they are rarely ever out of service, (c) deuterium-oxide (heavy water) moderator is expensive to manufacture, as a result, effective through valve leakage monitoring is essential. These three factors alone make CANDU sites the most suitable candidates for on line valve monitoring systems. Nuclear industry regulations have been instrumental in the development of 'at the valve' diagnostic systems, but diagnostic testing has not typically been utilized to the same degree in other less regulated industries. However, that trend is changing, and the move toward valve diagnostics and condition monitoring has moved fastest in the offshore oil and gas industry on the Norwegian side of the North Sea. The Ormen Lange plant, located on Nyhamna Island on the west coast of Norway, operated by Shell, is one of the worlds most advanced gas processing plants. A stated maintenance goal for the plant is that 70% of the maintenance budget and spend should be based on the results of on line condition monitoring, utilizing monitoring systems equipped with switch sensing, strain gages, hydraulic and pneumatic pressure transducers and

  1. On-line valve monitoring at the Ormen Lange gas plant

    Greenlees, R.; Hale, S.

    2011-01-01

    The purpose of this presentation is to discuss replacing time and labor intensive nuclear outage activities with on line condition monitoring solutions, primarily the periodic verification of MOV functionality discussed in USNRC Generic Letter 96.05. This regulation requires that MOV age related performance degradations are properly identified and accounted for, causing utilities to have to retest valves periodically for the duration of the plants operating license. AECL designed CANDU reactors have a world class performance and safety record, with typical average annual capacity factors of 90%. The CANDU reactor design has the ability to refuel on line, as a result (a) it can be a challenge scheduling all required valve testing into limited duration outage work windows, (b) at multi unit sites, Unit 0 valves can be difficult to test because they are rarely ever out of service, (c) deuterium-oxide (heavy water) moderator is expensive to manufacture, as a result, effective through valve leakage monitoring is essential. These three factors alone make CANDU sites the most suitable candidates for on line valve monitoring systems. Nuclear industry regulations have been instrumental in the development of 'at the valve' diagnostic systems, but diagnostic testing has not typically been utilized to the same degree in other less regulated industries. However, that trend is changing, and the move toward valve diagnostics and condition monitoring has moved fastest in the offshore oil and gas industry on the Norwegian side of the North Sea. The Ormen Lange plant, located on Nyhamna Island on the west coast of Norway, operated by Shell, is one of the worlds most advanced gas processing plants. A stated maintenance goal for the plant is that 70% of the maintenance budget and spend should be based on the results of on line condition monitoring, utilizing monitoring systems equipped with switch sensing, strain gages, hydraulic and pneumatic pressure transducers and acoustic leakage

  2. Bill Lang's contributions to acoustics at the International Business Machines Corp. (IBM) and to IBM in general

    Nobile, Matthew A.; Chu, Richard C.

    2005-09-01

    Although Bill Lang's accomplishments and key roles in national and international standards and in the formation of INCE are widely recognized, sometimes it has to be remembered that for nearly 35 years he also had a ``day job'' at the IBM Corporation. His achievements at IBM were no less significant and enduring than those in external standards and professional societies. This paper will highlight some of the accomplishments and activities of Bill Lang as an IBM noise control engineer, the creator of the IBM Acoustics Lab in Poughkeepsie, the founder of the global Acoustics program at IBM, and his many other IBM leadership roles. Bill was also a long-serving IBM manager, with the full set of personnel issues to deal with, so his people-management skills were often called into play. Bill ended his long and fruitful IBM career at a high point. In 1988, he took an original idea of his to the top of IBM executive management, which led directly to the formation of the IBM Academy of Technology, today the preeminent body of IBM top technical leaders from around the world.

  3. Analyzing the Effect of Spinning Process Variables on Draw Frame Blended Cotton Mélange Yarn Quality

    Ray, Suchibrata; Ghosh, Anindya; Banerjee, Debamalya

    2017-12-01

    An investigation has been made to study the effect of important spinning process variables namely shade depth, ring frame spindle speed and yarn twist multiplier (TM) on various yarn quality parameters like unevenness, strength, imperfection, elongation at break and hairiness index of draw frame blended cotton mélange yarn. Three factors Box and Behnken design of experiment has been used to conduct the study. The quadratic regression model is used to device the statistical inferences about sensitivity of the yarn quality parameters to the different process variables. The response surfaces are constructed for depicting the geometric representation of yarn quality parameters plotted as a function of process variables. Analysis of the results show that yarn strength of draw frame blended cotton mélange yarn is significantly affected by shade depth and TM. Yarn unevenness is affected by shade depth and ring frame spindle speed. Yarn imperfection level is mainly influenced by the shade depth and spindle speed. The shade depth and yarn TM have shown significant impact on yarn hairiness index.

  4. Verborgen carrières; oudere kunstenaars en een leven lang leren : een narratief PhD-onderzoek naar levenslang en levensbreed leren binnen de gevorderde beroepspraktijk van beeldende kunstenaars

    Delfgaauw, Leo

    2014-01-01

    Oudere Kunstenaars en een leven lang leren. ​Verborgen carrières: oudere kunstenaars en een leven lang leren. Een narratief-biografisch onderzoek naar levenslang en levensbreed leren binnen de gevorderde beroepspraktijk van beeldende kunstenaars. PhD-research Leo Delfgaauw. Promotoren: prof. dr.

  5. Jurassic-Paleogene intraoceanic magmatic evolution of the Ankara Mélange, north-central Anatolia, Turkey

    Sarifakioglu, E.; Dilek, Y.; Sevin, M.

    2014-02-01

    Oceanic rocks in the Ankara Mélange along the Izmir-Ankara-Erzincan suture zone (IAESZ) in north-central Anatolia include locally coherent ophiolite complexes (∼ 179 Ma and ∼ 80 Ma), seamount or oceanic plateau volcanic units with pelagic and reefal limestones (96.6 ± 1.8 Ma), metamorphic rocks with ages of 256.9 ± 8.0 Ma, 187.4 ± 3.7 Ma, 158.4 ± 4.2 Ma, and 83.5 ± 1.2 Ma indicating northern Tethys during the late Paleozoic through Cretaceous, and subalkaline to alkaline volcanic and plutonic rocks of an island arc origin (∼ 67-63 Ma). All but the arc rocks occur in a shale-graywacke and/or serpentinite matrix, and are deformed by south-vergent thrust faults and folds that developed in the middle to late Eocene due to continental collisions in the region. Ophiolitic volcanic rocks have mid-ocean ridge (MORB) and island arc tholeiite (IAT) affinities showing moderate to significant large ion lithophile elements (LILE) enrichment and depletion in Nb, Hf, Ti, Y and Yb, which indicate the influence of subduction-derived fluids in their melt evolution. Seamount/oceanic plateau basalts show ocean island basalt (OIB) affinities. The arc-related volcanic rocks, lamprophyric dikes and syenodioritic plutons exhibit high-K shoshonitic to medium- to high-K calc-alkaline compositions with strong enrichment in LILE, rare earth elements (REE) and Pb, and initial ɛNd values between +1.3 and +1.7. Subalkaline arc volcanic units occur in the northern part of the mélange, whereas the younger alkaline volcanic rocks and intrusions (lamprophyre dikes and syenodioritic plutons) in the southern part. The late Permian, Early to Late Jurassic, and Late Cretaceous amphibole-epidote schist, epidote-actinolite, epidote-chlorite and epidote-glaucophane schists represent the metamorphic units formed in a subduction channel in the northern Neotethys. The Middle to Upper Triassic neritic limestones spatially associated with the seamount volcanic rocks indicate that the northern

  6. Jurassic-Paleogene intra-oceanic magmatic evolution of the Ankara Mélange, North-Central Anatolia, Turkey

    Sarifakioglu, E.; Dilek, Y.; Sevin, M.

    2013-11-01

    Oceanic rocks in the Ankara Mélange along the Izmir-Ankara-Erzincan suture zone (IAESZ) in North-Central Anatolia include locally coherent ophiolite complexes (~179 Ma and ~80 Ma), seamount or oceanic plateau volcanic units with pelagic and reefal limestones (96.6 ± 1.8 Ma), metamorphic rocks with ages of 187.4 ± 3.7 Ma, 158.4 ± 4.2 Ma, and 83.5 ± 1.2 Ma, and subalkaline to alkaline volcanic and plutonic rocks of an island arc origin (~67-63 Ma). All but the arc rocks occur in a shaly-graywacke and/or serpentinite matrix, and are deformed by south-vergent thrust faults and folds that developed in the Middle to Late Eocene due to continental collisions in the region. Ophiolitic volcanic rocks have mid-ocean ridge (MORB) and island arc tholeiite (IAT) affinities showing moderate to significant LILE enrichment and depletion in Nb, Hf, Ti, Y and Yb, which indicate the influence of subduction-derived fluids in their melt evolution. Seamount/oceanic plateau basalts show ocean island basalt (OIB) affinities. The arc-related volcanic rocks, lamprophyric dikes and syeno-dioritic plutons exhibit high-K shoshonitic to medium-to high-K calc-alkaline compositions with strong enrichment in LILE, REE and Pb, and initial ϵNd values between +1.3 and +1.7. Subalkaline arc volcanic units occur in the northern part of the mélange, whereas the younger alkaline volcanic rocks and intrusions (lamprophyre dikes and syeno-dioritic plutons) in the southern part. The Early to Late Jurassic and Late Cretaceous epidote-actinolite, epidote-chlorite and epidote-glaucophane schists represent the metamorphic units formed in a subduction channel in the Northern Neotethys. The Middle to Upper Triassic neritic limestones spatially associated with the seamount volcanic rocks indicate that the Northern Neotethys was an open ocean with its MORB-type oceanic lithosphere by the Early Triassic. The Latest Cretaceous-Early Paleocene island arc volcanic, dike and plutonic rocks with

  7. Disfagia orofaríngea em crianças com síndrome Cornélia de Lange Oropharyngeal dysphagia in children with Cornelia de Lange syndrome

    Priscila Martins Foroni

    2010-10-01

    Full Text Available OBJETIVO: descrever os achados das fases oral e faríngea da deglutição, bem como os aspectos sensório-motores orofaciais relevantes em crianças com a síndrome Cornélia de Lange. MÉTODOS: trata-se de relato de caso, retrospectivo. Realizou-se análise descritiva de quatro protocolos de avaliação fonoaudiológica da deglutição da rotina do Serviço de Fonoaudiologia de crianças com a síndrome Cornélia de Lange, de ambos os sexos, com faixa etária entre 1:2 e 9:6 anos, encaminhadas para avaliação clínica e videofluoroscópica da deglutição em um hospital público universitário. Analisou-se os aspectos das fases oral e faríngea da deglutição por meio da avaliação clínica do sistema sensório-motor orofacial, avaliação clínica funcional e videofluoroscópica. RESULTADOS: As alterações do sistema sensório-motor orofacial mais encontradas foram a hipersensibilidade e a hipertonia muscular da região orofacial. Na fase oral da deglutição, dentre as alterações observadas, destacaram-se a presença de vedamento labial ineficiente, escape oral anterior do bolo alimentar, inadequada formação/organização do bolo e ejeção oral deficiente. Na fase faríngea, observou-se ausculta cervical alterada, refluxo nasal, excursão hiolaríngea reduzida, presença de resíduo em trânsito faríngeo após a deglutição, penetração laríngea e aspiração laringotraqueal. A disfagia orofaríngea foi encontrada em todas as crianças. CONCLUSÃO: Os achados encontrados apontaram alterações nos aspectos sensório-motores orofaciais e comprometimento na biomecânica da deglutição. As importantes alterações na deglutição evidenciadas nos casos descritos podem corresponder a manifestações típicas da síndrome Cornélia de Lange.PURPOSE: to describe the findings for the oral and pharyngeal phases of swallowing, as well as the relevant orofacial sensorimotor aspects for children with Cornelia de Lange syndrome. METHODS

  8. TBT-gehalten en effecten bij de Gewone Alikruik (Littorina littorea) en de Gevlochten Fuikhoorn (Nassarius reticulatus) langs de Nederlandse kust in 2010

    Kaag, N.H.B.M.; Jol, J.G.; Hoek-van Nieuwenhuizen, van M.

    2012-01-01

    Sinds 2005 analyseert IMARES in opdracht van Rijkswaterstaat (RIKZ, later de Waterdienst) het voorkomen van intersex bij de Gewone Alikruik (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met

  9. TBT-gehalten en effecten bij de Gewone Alikruik, de Gevlochten Fuikhoorn en de Purperslak langs de Nederlandse kust in 2012

    Hoek-van Nieuwenhuizen, van M.; Jol, J.G.; Kaag, N.H.B.M.

    2013-01-01

    Sinds 2005 analyseert IMARES in opdracht van Rijkswaterstaat (RIKZ, later de Waterdienst) het voorkomen van intersex bij de Gewone Alikruiken (Littorina littorea) die op vaste locaties langs de Nederlandse kust verzameld worden. Het doel van dit onderzoek is effecten van verontreiniging met

  10. Genetic syndromes in the family : child characteristics and parenting stress in Angelman, CHARGE, Cornelia de Lange, Prader-Willi, and Rett syndrome

    Wulffaert, Josette

    2010-01-01

    Aim of the dissertation: To expand the knowledge on the behavioural phenotypes, level of parenting stress and the relationship between child characteristics and parenting stress in five genetic syndromes. The included syndromes are Angelman, CHARGE, Cornelia de Lange, Prader-Willi, and Rett

  11. Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016

    Kline, Antonie D.; Krantz, Ian D.; Deardorff, Matthew A.; Shirahige, Katsuhiko; Dorsett, Dale; Gerton, Jennifer L.; Wu, Meng; Mehta, Devanshi; Mills, Jason A.; Carrico, Cheri S.; Noon, Sarah; Herrera, Pamela S.; Horsfield, Julia A.; Bettale, Chiara; Morgan, Jeremy; Huisman, Sylvia A.; Moss, Jo; McCleery, Joseph; Grados, Marco; Hansen, Blake D.; Srivastava, Siddharth; Taylor-Snell, Emily; Kerr, Lynne M.; Katz, Olivia; Calof, Anne L.; Musio, Antonio; Egense, Alena; Haaland, Richard E.

    2017-01-01

    Cornelia de Lange Syndrome (CdLS) is due to mutations in the genes for the structural and regulatory proteins that make up the cohesin complex, and is considered a cohesinopathy disorder or, more recently, a transcriptomopathy. New phenotypes have been recognized in this expanding field. There are

  12. Mechanisms and processes of stratal disruption and mixing in the development of melanges and broken formations: Redefining and classifying melanges : Redefining and classifying mélanges

    Festa, A.; Dilek, Yildirim; Pini, Gian Andrea; Codegone, Giulia; Ogata, K.

    2012-01-01

    The terms mélange and broken formation have been used in different ways in the literature. The lack of agreement on their definition often leads to confusion and misinterpretations. An evaluation of the various uses of these terms allows us to consider several types of chaotic rock bodies originated

  13. Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue

    Zhang, Miao; D'Aniello, Cristina; Verkerk, Arie O.; Wrobel, Eva; Frank, Stefan; Ward-van Oostwaard, Dorien; Piccini, Ilaria; Freund, Christian; Rao, Jyoti; Seebohm, Guiscard; Atsma, Douwe E.; Schulze-Bahr, Eric; Mummery, Christine L.; Greber, Boris; Bellin, Milena

    2014-01-01

    Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening cardiac arrhythmias. Patients display delayed cardiac repolarization, associated high risk of sudden death due to ventricular tachycardia, and congenital bilateral deafness. In contrast to the autosomal dominant

  14. Zamanın Bir Başlangıcı Olmalı mıdır?

    Zikri Yavuz

    2015-12-01

    Full Text Available Bu makalede, zamanın bir başlangıcı olup olmadığını tartışacağım. Büyük patlama modeline göre, evrenimiz sonsuz bir şekilde geçmişe sahip değildir. Bu, muhtemelen modern kozmolojinin en görkemli keşiflerinden birisidir. Buna rağmen bazı filozoflar zamanın zorunlu olarak bir başlangıcının olmadığını iddia etmektedirler. Büyük patlamanın âlemin zamansal bir başlangıcı olduğu görüşünü desteklediğini ileri süreceğim. Aynı zamanda zamanın başlangıcı olmadığına dair a priori argümanların da başarılı olmadığını göstermeyi deneyeceğim.

  15. Research in action: from AIDS to global health to impact. A symposium in recognition of the scientific contributions of Professor Joep Lange

    Boender, T. Sonia; Barré-Sinoussi, Françoise; Cooper, David; Goosby, Eric; Hankins, Catherine; Heidenrijk, Michiel; de Jong, Menno; Kazatchkine, Michel; Laoye, Fola; Merson, Michael; Reiss, Peter; Rinke de Wit, Tobias F.; Rogo, Khama; Schellekens, Onno; Schultsz, Constance; Sigaloff, Kim C. E.; Simon, John; Zewdie, Debrework

    2015-01-01

    On Tuesday 14 October 2014, 850 family members, friends, colleagues, prominent scientists and dignitaries from all over the world gathered in Amsterdam to pay tribute to the lives and legacies of Joep Lange and Jacqueline van Tongeren. The remembrance was held at the Amsterdam Medical Centre (AMC)

  16. NOAA TIFF Image - Bathymetry - Lang bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83

    National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a 1 meter resolution bathymetry of the reef shelf and the steep slopes of Lang Bank (H12639) of St. Croix, US Virgin Islands. The M-I907-NF-14...

  17. Model theory and algebraic geometry an introduction to E. Hrushovski’s proof of the geometric Mordell-Lang conjecture

    1998-01-01

    This introduction to the recent exciting developments in the applications of model theory to algebraic geometry, illustrated by E. Hrushovski's model-theoretic proof of the geometric Mordell-Lang Conjecture starts from very basic background and works up to the detailed exposition of Hrushovski's proof, explaining the necessary tools and results from stability theory on the way. The first chapter is an informal introduction to model theory itself, making the book accessible (with a little effort) to readers with no previous knowledge of model theory. The authors have collaborated closely to achieve a coherent and self- contained presentation, whereby the completeness of exposition of the chapters varies according to the existence of other good references, but comments and examples are always provided to give the reader some intuitive understanding of the subject.

  18. "Virtual shear box" experiments of stress and slip cycling within a subduction interface mélange

    Webber, Sam; Ellis, Susan; Fagereng, Åke

    2018-04-01

    What role does the progressive geometric evolution of subduction-related mélange shear zones play in the development of strain transients? We use a "virtual shear box" experiment, based on outcrop-scale observations from an ancient exhumed subduction interface - the Chrystalls Beach Complex (CBC), New Zealand - to constrain numerical models of slip processes within a meters-thick shear zone. The CBC is dominated by large, competent clasts surrounded by interconnected weak matrix. Under constant slip velocity boundary conditions, models of the CBC produce stress cycling behavior, accompanied by mixed brittle-viscous deformation. This occurs as a consequence of the reorganization of competent clasts, and the progressive development and breakdown of stress bridges as clasts mutually obstruct one another. Under constant shear stress boundary conditions, the models show periods of relative inactivity punctuated by aseismic episodic slip at rapid rates (meters per year). Such a process may contribute to the development of strain transients such as slow slip.

  19. Pompe de chaleur fonctionnant avec un mélange de fluides Heat Pump Operating with a Fluid Mixture

    Vidal J.

    2006-11-01

    Full Text Available Lorsqu'une pompe de chaleur échange de la chaleur avec des fluides extérieurs, dont la température évolue au cours de l'échange, il est possible d'augmenter le coefficient de performance en utilisant comme fluide de travail un mélange non-azéotropique qui se vaporise et se condense suivant une évolution de température parallèle à celle du fluide extérieur avec lequel s'effectue cet échange. L'utilisation de mélanges dans les pompes de chaleur a été étudiée, d'une part, au moyen de modèles de simulation sur ordinateur et, d'autre part, au moyen d'essais expérimentaux. Différentes applications ont été examinées à la fois dans le domaine du chauffage résidentiel et dans le domaine industriel. Whenever heat is recovered and delivered, the coefficient of performance of a heat pump can be increased by using a fluid mixture selected to have a temperature variation, during the vaporization and condensation stages, parallel to that of the outside fluid with which the heat exchange takes place. Such a solution was investigated both theoretically and experimentally. It has been shown that significant savings can be expected, ranging up to 50% of the energy consumption of conventional heat pumps in some cases. Various applications for home and industrial heating have been examined, and the economic prospects have been found to be satisfactory. Further work is needed to develop such heat pumps on a commercial basis.

  20. Alimentation des moteurs en mélange homogène pauvre Feeding Homogeneous Lean Mixtures to Engines

    Rayna B.

    2006-11-01

    Full Text Available Les études effectuées dans le cadre de plusieurs conventions de recherche entre l'Institut de Recherche des Transports (IRT et l'Institut Français du Pétrole (IFP associé à d'autres organismes industriels (Régie Nationale des Usines Renault (RNUR, Solex... ont permis a de caractériser l'influence de la préparation physique du mélange air-carburant sur le fonctionnement de moteurs monocylindre et multicylindre. L'effet sur le rendement d'inégalités de richesse entre les cylindres a été estimé à l'aide d'un modèle mathématique de simulation du moteur à allumage commandé ; b d'analyser les défauts inhérents à certains systèmes d'alimentation actuels et d'expérimenter des techniques différentes de formation du mélange carburé (car-burateur à dépression constante, pulvérisation pneumatique du carburant. Les résultats obtenus ont montré notamment que des améliorations ne peuvent résulter que d'un aménagement d'ensemble de tous les éléments du circuit d'admission Investigations carried out under thé terms of several research agreements involving Institut de Recherche des Transports (IRT and Institut Français du Pétrole (IFP associated with other industrial organizations (Régie Nationale des Usines Renault (RNUR, Solex served ta a Characterize thé influence of thé physical preparation of thé air/fuel mixture on thé operating of single-cylinder and multicylinder engines. The effect on thé efficiency of unequal air/fuel ratios among thé cylindres was evaluated by a mathematical model used ta simulate a spark-ignition engine. b Analyze thé inhérent defects of some fuel-supply systems now used and ta experiment with différent techniques of mixture preparation (constant depression car-burettor, pneumatic fuel spraying. The results obtained show, in particulor, that improvements con be produced only by redesigning all thé parts of thé fuel-supply circuit.

  1. [Lange, Thomas. Zwischen Reformation und Untergang Alt-Livlands. Der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer] / Madis Maasing

    Maasing, Madis, 1984-

    2014-01-01

    Arvustus: Lange, Thomas. Zwischen Reformation und Untergang Alt-Livlands. Der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer

  2. NOAA TIFF Image - Backscatter - Lang Bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83 (NCEI Accession 0128255)

    National Oceanic and Atmospheric Administration, Department of Commerce — This geotiff represents a 1 meter resolution backscatter mosaic of the reef shelf and the steep slopes of the Lang Bank (H12639) of St. Croix, US Virgin Islands. The...

  3. A 6-year-old boy with Cornelia de Lange syndrome and Coats disease: case report and review of the literature.

    Stacey, Andrew W; Sparagna, Cristina; Borri, Melissa; Rizzo, Stanislao; Hadjistilianou, Theodora

    2015-10-01

    Cornelia de Lange syndrome (CdLS) can result in multiple congenital abnormalities and numerous ocular findings. We report the case of a 6-year-old boy with history of CdLS who presented with Coats disease. The findings in this case are compared to those found in the two previously reported cases of concomitant CdLS and Coats disease. The low incidence of these two disorders makes it highly unlikely that the connection is random in these 3 cases. The number of patients with both Cornelia de Lange syndrome and Coats disease is likely underestimated due to the difficulty in examining the peripheral retina in this patient population. Copyright © 2015 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

  4. Birma - otsekui retk minevikku / Mait Talts

    Talts, Mait, 1964-

    2011-01-01

    Reisist Birmasse, tänapäevase nimega Myanmari, mida Eestiga seovad sinna maetud "Eestimaa budistlikud peapiiskopid" Karl A.M. Tõnisson-Tennisons (Vend Vahindra, 1883-1962) ja Friedrich Voldemar Lustig (Ashin Ananda, 1912-1989)

  5. MAIT cells: new guardians of the liver

    Kurioka, Ayako; Walker, Lucy J; Klenerman, Paul; Willberg, Christian B

    2016-01-01

    The liver is an important immunological organ that remains sterile and tolerogenic in homeostasis, despite continual exposure to non-self food and microbial-derived products from the gut. However, where intestinal mucosal defenses are breached or in the presence of a systemic infection, the liver acts as a second 'firewall', because of its enrichment with innate effector cells able to rapidly respond to infections or tissue dysregulation. One of the largest populations of T cells within the h...

  6. Rapport om kystsikringsforsøg ved anvendelse af lodrette drænrør langs Hjørring Kommunes kyststrækning

    Burcharth, Hans F.

    Med økonomisk støtte fra Erhversfremmestyrelsen har Hjørring Kommune i samarbejde med Skagen Innovationscenter, SIC, gennemført et kystsikringsforsøg med anvendelse af lodrette drænrør over en 3.7 km lang kyststraekning fra Skallerup Klit ti1 Nørlev nord. Strækningen er stationeret St. 0,0 - St 3...

  7. Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: abstracts from the 2014 Scientific and Educational Symposium.

    Kline, Antonie D; Calof, Anne L; Lander, Arthur D; Gerton, Jennifer L; Krantz, Ian D; Dorsett, Dale; Deardorff, Matthew A; Blagowidow, Natalie; Yokomori, Kyoko; Shirahige, Katsuhiko; Santos, Rosaysela; Woodman, Julie; Megee, Paul C; O'Connor, Julia T; Egense, Alena; Noon, Sarah; Belote, Maurice; Goodban, Marjorie T; Hansen, Blake D; Timmons, Jenni Glad; Musio, Antonio; Ishman, Stacey L; Bryan, Yvon; Wu, Yaning; Bettini, Laura R; Mehta, Devanshi; Zakari, Musinu; Mills, Jason A; Srivastava, Siddharth; Haaland, Richard E

    2015-06-01

    Cornelia de Lange Syndrome (CdLS) is the most common example of disorders of the cohesin complex, or cohesinopathies. There are a myriad of clinical issues facing individuals with CdLS, particularly in the neurodevelopmental system, which also have implications for the parents and caretakers, involved professionals, therapists, and schools. Basic research in developmental and cell biology on cohesin is showing significant progress, with improved understanding of the mechanisms and the possibility of potential therapeutics. The following abstracts are presentations from the 6th Cornelia de Lange Syndrome Scientific and Educational Symposium, which took place on June 25-26, 2014, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting in Costa Mesa, CA. The Research Committee of the CdLS Foundation organizes the meeting, reviews and accepts abstracts, and subsequently disseminates the information to the families through members of the Clinical Advisory Board. In addition to the scientific and clinical discussions, there were educationally focused talks related to practical aspects of behavior and development. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. © 2015 Wiley Periodicals, Inc.

  8. Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts.

    Kline, Antonie D; Calof, Anne L; Schaaf, Cheri A; Krantz, Ian D; Jyonouchi, Soma; Yokomori, Kyoko; Gauze, Maria; Carrico, Cheri S; Woodman, Julie; Gerton, Jennifer L; Vega, Hugo; Levin, Alex V; Shirahige, Katsuhiko; Champion, Michele; Goodban, Marjorie T; O'Connor, Julia T; Pipan, Mary; Horsfield, Julia; Deardorff, Matthew A; Ishman, Stacey L; Dorsett, Dale

    2014-06-01

    Cornelia de Lange syndrome (CdLS) is the prototype for the cohesinopathy disorders that have mutations in genes associated with the cohesin subunit in all cells. Roberts syndrome is the next most common cohesinopathy. In addition to the developmental implications of cohesin biology, there is much translational and basic research, with progress towards potential treatment for these conditions. Clinically, there are many issues in CdLS faced by the individual, parents and caretakers, professionals, and schools. The following abstracts are presentations from the 5th Cornelia de Lange Syndrome Scientific and Educational Symposium on June 20-21, 2012, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting, Lincolnshire, IL. The research committee of the CdLS Foundation organizes the meeting, reviews and accepts abstracts and subsequently disseminates the information to the families. In addition to the basic science and clinical discussions, there were educationally-focused talks related to practical aspects of management at home and in school. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. © 2014 Wiley Periodicals, Inc.

  9. Patients Carrying 9q31.1-q32 Deletion Share Common Features with Cornelia de Lange Syndrome

    Ruixue Cao

    2015-01-01

    Full Text Available Background: Cornelia de Lange Syndrome (CdLS is a rare but severe clinically heterogeneous developmental disorder characterized by facial dysmorphia, growth and cognitive retardation, and abnormalities of limb development. Objectives: To determine the pathogenesis of a patient with CdLS. Methods: We studied a patient with CdLS by whole exome sequencing, karyotyping and Agilent CGH Array. The results were confirmed by quantitative real-time PCR analysis of the patient and her parents. Further comparison of our patient and cases with partially overlapping deletions retrieved from the literature and databases was undertaken. Results: Whole exome sequencing had excluded the mutation of cohesion genes such as NIPBL,SMC1A and SMC3. The result of karyotyping showed a deletion of chromosome 9q31.1-q32 and the result of Agilent CGH Array further displayed a 12.01-Mb region of deletion at chromosome bands 9q31.1-q32. Reported cases with the deletion of 9q31.1-q32 share similar features with our CdLS patient. One of the genes in the deleted region, SMC2, belongs to the Structural Maintenance of Chromosomes (SMC family and regulates gene expression and DNA repair. Conclusions: Patients carrying the deletion of 9q31.1-q32 showed similar phenotypes with CdLS.

  10. Suppressive and Enhancing Effects in Early Visual Cortex during Illusory Shape Perception: A Comment on Kok and de Lange (2014

    Pieter Moors

    2015-02-01

    Full Text Available In a recent functional magnetic resonance imaging study, Kok and de Lange (2014 observed that BOLD activity for a Kanizsa illusory shape stimulus, in which pacmen-like inducers elicit an illusory shape percept, was either enhanced or suppressed relative to a nonillusory control configuration depending on whether the spatial profile of BOLD activity in early visual cortex was related to the illusory shape or the inducers, respectively. The authors argued that these findings fit well with the predictive coding framework, because top-down predictions related to the illusory shape are not met with bottom-up sensory input and hence the feedforward error signal is enhanced. Conversely, for the inducing elements, there is a match between top-down predictions and input, leading to a decrease in error. Rather than invoking predictive coding as the explanatory framework, the suppressive effect related to the inducers might be caused by neural adaptation to perceptually stable input due to the trial sequence used in the experiment.

  11. Study variation of PM-10 air pollution at Lang Meteorological Station, Hanoi Coded: CS/02/04-06

    Vuong Thu Bac; Dinh Thien Lam; Ngyen Thi Hong Thinh; Dang Duc Nhan; Nguyen Hao Quang; Pham Duy Hien

    2003-01-01

    577 air dust samples have been collected with two kinds of air samplers (2-SFU, 1-ASP) on every Wednesday and Sunday for 24 hours at both of monitoring stations (Lang - Hanoi and Lucnam - Bacgiang). PM(2.5), PM(2.5-10), PM(10) and BC concentrations in 452 air dust samples have been determined. 9032 data have been analyzed with many of different multi-elements analytical techniques (IC: 264 samples x 9 ions, PIXE: 388 samples x 15 elements, XRF: 48 samples x 8 elements, LR: 452 samples x 1 element). Over 6000 of meteorological parameters (T, Rain, WS, WD, RH...) have been collected and processed.Variations and levels of air dust concentrations and BC in Hanoi from 1998 to 2002 have been studied. PM(2.5), PM(2.5-10), PM(10) and BC concentrations and BC obviously periodically vary. They reach maximum in the winter season, especially in December and January, sometimes they reached 300-400 μg.m -3 , They reach minimum in the summer season, sometimes they went down 10 μg.m -3 on rainy days. These variations were affected by meteorological parameters. PM(2.5), PM(10) daily average concentrations in Hanoi are greater than the American air standards (PM(2.5): 65 μg.m -3 , PM(10): 150 μg.m -3 ) in many days and their yearly average concentrations are also far exceeded. Air dust pollution levels in Hanoi are higher than in developed countries and even countries in the region. BC (5.9 μg.m -3 ) concentration and Pb (0.11 μg.m -3 ) are also higher than in many countries. (VTB)

  12. Benefits and limitations of a multidisciplinary approach to individualized management of Cornelia de Lange syndrome and related diagnoses.

    January, Kathleen; Conway, Laura J; Deardorff, Matthew; Harrington, Ann; Krantz, Ian D; Loomes, Kathleen; Pipan, Mary; Noon, Sarah E

    2016-06-01

    Given the clinical complexities of Cornelia de Lange Syndrome (CdLS), the Center for CdLS and Related Diagnoses at The Children's Hospital of Philadelphia (CHOP) and The Multidisciplinary Clinic for Adolescents and Adults at Greater Baltimore Medical Center (GBMC) were established to develop a comprehensive approach to clinical management and research issues relevant to CdLS. Little work has been done to evaluate the general utility of a multispecialty approach to patient care. Previous research demonstrates several advantages and disadvantages of multispecialty care. This research aims to better understand the benefits and limitations of a multidisciplinary clinic setting for individuals with CdLS and related diagnoses. Parents of children with CdLS and related diagnoses who have visited a multidisciplinary clinic (N = 52) and who have not visited a multidisciplinary clinic (N = 69) were surveyed to investigate their attitudes. About 90.0% of multispecialty clinic attendees indicated a preference for multidisciplinary care. However, some respondents cited a need for additional clinic services including more opportunity to meet with other specialists (N = 20), such as behavioral health, and increased information about research studies (N = 15). Travel distance and expenses often prevented families' multidisciplinary clinic attendance (N = 41 and N = 35, respectively). Despite identified limitations, these findings contribute to the evidence demonstrating the utility of a multispecialty approach to patient care. This approach ultimately has the potential to not just improve healthcare for individuals with CdLS but for those with medically complex diagnoses in general. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  13. L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome.

    Xu, Baoshan; Sowa, Nenja; Cardenas, Maria E; Gerton, Jennifer L

    2015-03-15

    Cohesinopathies are human genetic disorders that include Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) and are characterized by defects in limb and craniofacial development as well as mental retardation. The developmental phenotypes of CdLS and other cohesinopathies suggest that mutations in the structure and regulation of the cohesin complex during embryogenesis interfere with gene regulation. In a previous project, we showed that RBS was associated with highly fragmented nucleoli and defects in both ribosome biogenesis and protein translation. l-leucine stimulation of the mTOR pathway partially rescued translation in human RBS cells and development in zebrafish models of RBS. In this study, we investigate protein translation in zebrafish models of CdLS. Our results show that phosphorylation of RPS6 as well as 4E-binding protein 1 (4EBP1) was reduced in nipbla/b, rad21 and smc3-morphant embryos, a pattern indicating reduced translation. Moreover, protein biosynthesis and rRNA production were decreased in the cohesin morphant embryo cells. l-leucine partly rescued protein synthesis and rRNA production in the cohesin morphants and partially restored phosphorylation of RPS6 and 4EBP1. Concomitantly, l-leucine treatment partially improved cohesinopathy embryo development including the formation of craniofacial cartilage. Interestingly, we observed that alpha-ketoisocaproate (α-KIC), which is a keto derivative of leucine, also partially rescued the development of rad21 and nipbla/b morphants by boosting mTOR-dependent translation. In summary, our results suggest that cohesinopathies are caused in part by defective protein synthesis, and stimulation of the mTOR pathway through l-leucine or its metabolite α-KIC can partially rescue development in zebrafish models for CdLS. © The Author 2014. Published by Oxford University Press.

  14. Premixed Turbulent Flames and Spectral Approach Flammes turbulentes de prémélange Approche spectrale

    Mathieu J.

    2006-11-01

    the behaviour of flames developing in a turbulent field can be easily understood. This approach could also open the way to new modeling methods. Indépendamment de l'intérêt scientifique que présentent les flammes de prémélange, les applications industrielles sont nombreuses. Dans cet article la flamme est supposée se développer dans un milieu turbulent ce qui oblige à une comparaison précise des échelles associées à la flamme et de celles associées à la turbulence. Cette confrontation n'est pas nouvelle. Cet article montre que ces comparaisons peuvent s'enrichir si l'on accepte une description spectrale de la turbulence faisant largement référence à de nombreux travaux antérieurs. La notion de champ extérieur turbulent agissant sur la flamme et celle de champ turbulent envahissant la flamme apparaît clairement lors d'une représentation spectrale. On voit également comment l'on passe continûment d'une situation avec front de réaction à une autre où la réaction s'effectue en volume tandis que se développe une compétition entre une réaction chimique qui tend à générer une ségrégation des espèces et une diffusion turbulente qui provoque le mélange. Dans les moteurs à combustion avec prémélange il existe un grand nombre de situations possibles dépendant de la vitesse de rotation. On conçoit aisément qu'une modélisation unique valable quel que soit le régime ne soit guère envisageable. Il y a là aussi matière à réflexions. Autre sujet au demeurant ouvert est celui de la modélisation. Dans le présent article certaines structures turbulentes sont étudiées. Resterait à savoir si une architecture spécifique de moteur n'est pas capable de générer des structures turbulentes particulières. Jusqu'ici le rôle de tourbillons privilégiés avait été introduit par la voie de séquences de tourbillons. L'approche spectrale permet de considérer un ensemble continu de structures analogues intervenant dans un phénomène de

  15. Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016.

    Kline, Antonie D; Krantz, Ian D; Deardorff, Matthew A; Shirahige, Katsuhiko; Dorsett, Dale; Gerton, Jennifer L; Wu, Meng; Mehta, Devanshi; Mills, Jason A; Carrico, Cheri S; Noon, Sarah; Herrera, Pamela S; Horsfield, Julia A; Bettale, Chiara; Morgan, Jeremy; Huisman, Sylvia A; Moss, Jo; McCleery, Joseph; Grados, Marco; Hansen, Blake D; Srivastava, Siddharth; Taylor-Snell, Emily; Kerr, Lynne M; Katz, Olivia; Calof, Anne L; Musio, Antonio; Egense, Alena; Haaland, Richard E

    2017-05-01

    Cornelia de Lange Syndrome (CdLS) is due to mutations in the genes for the structural and regulatory proteins that make up the cohesin complex, and is considered a cohesinopathy disorder or, more recently, a transcriptomopathy. New phenotypes have been recognized in this expanding field. There are multiple clinical issues facing individuals with all forms of CdLS, particularly in the neurodevelopmental system, but also gastrointestinal, cardiac, and musculoskeletal. Aspects of developmental and cell biology have found common endpoints in the biology of the cohesin complex, with improved understanding of the mechanisms, easier diagnostic tests, and the possibility of potential therapeutics, all major clinical implications for the individual with CdLS. The following abstracts are the presentations from the 7th Cornelia de Lange Syndrome Scientific and Educational Symposium, June 22-23, 2016, in Orlando, FL, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting. In addition to the scientific and clinical discussions, there were talks related to practical aspects of behavior including autism, transitions, communication, access to medical care, and databases. At the end of the symposium, a panel was held, which included several parents, affected individuals and genetic counselors, and discussed the greatest challenges in life and how this information can assist in guiding future research. The Research Committee of the CdLS Foundation organizes this meeting, reviews, and accepts abstracts, and subsequently disseminates the information to the families through members of the Clinical Advisory Board and publications. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. © 2017 Wiley Periodicals, Inc.

  16. Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016

    Kline, Antonie D.; Krantz, Ian D.; Deardorff, Matthew A.; Shirahige, Katsuhiko; Dorsett, Dale; Gerton, Jennifer L.; Wu, Meng; Mehta, Devanshi; Mills, Jason A.; Carrico, Cheri S.; Noon, Sarah; Herrera, Pamela S.; Horsfield, Julia A.; Bettale, Chiara; Morgan, Jeremy; Huisman, Sylvia A.; Moss, Jo; McCleery, Joseph; Grados, Marco; Hansen, Blake D.; Srivastava, Siddharth; Taylor-Snell, Emily; Kerr, Lynne M.; Katz, Olivia; Calof, Anne L.; Musio, Antonio; Egense, Alena; Haaland, Richard E.

    2017-01-01

    Cornelia de Lange Syndrome (CdLS) is due to mutations in the genes for the structural and regulatory proteins that make up the cohesin complex, and is considered a cohesinopathy disorder or, more recently, a transcriptomopathy. New phenotypes have been recognized in this expanding field. There are multiple clinical issues facing individuals with all forms of CdLS, particularly in the neurodevelopmental system, but also gastrointestinal, cardiac, and musculoskeletal. Aspects of developmental and cell biology have found common endpoints in the biology of the cohesin complex, with improved understanding of the mechanisms, easier diagnostic tests, and the possibility of potential therapeutics, all major clinical implications for the individual with CdLS. The following abstracts are the presentations from the 7th Cornelia de Lange Syndrome Scientific and Educational Symposium, June 22–23, 2016, in Orlando, FL, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting. In addition to the scientific and clinical discussions, there were talks related to practical aspects of behavior including autism, transitions, communication, access to medical care, and databases. At the end of the symposium, a panel was held, which included several parents, affected individuals and genetic counselors, and discussed the greatest challenges in life and how this information can assist in guiding future research. The Research Committee of the CdLS Foundation organizes this meeting, reviews, and accepts abstracts, and subsequently disseminates the information to the families through members of the Clinical Advisory Board and publications. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD. PMID:28190301

  17. Neotethyan rifting-related ore occurrences: study of an accretionary mélange complex (Darnó Unit, NE Hungary

    Kiss Gabriella B.

    2016-02-01

    Full Text Available The geology of the NE Hungarian Darnó Unit is rather complicated, as it is composed mostly of a Jurassic accretionary mélange complex, according to the most recent investigations. The magmatic and sedimentary rock blocks of the mélange represent products of different evolutionary stages of the Neotethys; including Permian and Triassic sedimentary rocks of marine rifting related origin, Triassic pillow basalt of advanced rifting related origin and Jurassic pillow basalt originated in back-arc-basin environment. This small unit contains a copper-gold occurrence in the Permian marly-clayey limestone, an iron enrichment in the Triassic sedimentary succession, a copper-silver ore occurrence in Triassic pillow basalts and a copper ore indication, occurring both in the Triassic and Jurassic pillow basalts. The present study deals with the Cu(-Ag occurrence in the Triassic basalt and the Fe occurrence in the Triassic sedimentary succession. The former shows significant similarities with the Michigan-type mineralizations, while the latter has typical characteristics of the Fe-SEDEX deposits. All the above localities fit well into the new geological model of the investigated area. The mineralizations represent the different evolutionary stages of the Neotethyan rifting and an epigenetic, Alpine metamorphism-related process and their recent, spatially close position is the result of the accretionary mélange formation. Thus, the Darnó Unit represents a perfect natural laboratory for studying and understanding the characteristic features of several different rifting related ore forming processes.

  18. Concomitant posterior hip dislocation, ipsilateral intertrochanteric- and proximal tibial- fractures with popliteal artery injury: a challenging trauma mélange

    Pranit N. Chotai

    2015-12-01

    Full Text Available Constellation of ipsilateral posterior hip dislocation, intertrochanteric- and proximal tibial fracture with popliteal artery injury is rare. Management of this presentation is challenging. A motor vehicle accident victim presented with these injuries, but without any initial signs of vascular compromise. Popliteal artery injury was diagnosed intra-operatively and repaired. This was followed by external fixation of tibial fracture, open reduction of dislocated hip and internal fixation of intertrochanteric fracture. Patient regained bilateral complete weight bearing and returned to pre-accident activity level. Apt surgical management including early repair of vascular injury in such a trauma mélange allows for a positive postoperative outcome.

  19. Structural context and variation of ocean plate stratigraphy, Franciscan Complex, California: insight into mélange origins and subduction-accretion processes

    Wakabayashi, John

    2017-12-01

    The transfer (accretion) of materials from a subducting oceanic plate to a subduction-accretionary complex has produced rock assemblages recording the history of the subducted oceanic plate from formation to arrival at the trench. These rock assemblages, comprising oceanic igneous rocks progressively overlain by pelagic sedimentary rocks (chert and/or limestone) and trench-fill clastic sedimentary rocks (mostly sandstone, shale/mudstone), have been called ocean plate stratigraphy (OPS). During accretion of OPS, megathrust slip is accommodated by imbricate faults and penetrative strain, shortening the unit and leading to tectonic repetition of the OPS sequence, whereas OPS accreted at different times are separated by non-accretionary megathrust horizons. The Franciscan subduction complex of California accreted episodically over a period of over 150 million years and incorporated OPS units with a variety of characteristics separated by non-accretionary megathrust horizons. Most Franciscan OPS comprises MORB (mid-ocean-ridge basalt) progressively overlain by chert and trench-fill clastic sedimentary rocks that are composed of variable proportions of turbidites and siliciclastic and serpentinite-matrix olistostromes (sedimentary mélanges). Volumetrically, the trench-fill component predominates in most Franciscan OPS, but some units have a significant component of igneous and pelagic rocks. Ocean island basalt (OIB) overlain by limestone is less common than MORB-chert assemblages, as are abyssal serpentinized peridotite slabs. The earliest accreted OPS comprises metabasite of supra-subduction zone affinity imbricated with smaller amounts of metaultramafic rocks and metachert, but lacking a clastic component. Most deformation of Franciscan OPS is localized along discrete faults rather than being distributed in the form of penetrative strain. This deformation locally results in block-in-matrix tectonic mélanges, in contrast to the sedimentary mélanges making up part of

  20. Kurbade naer / Anne Lange

    Lange, Anne

    1998-01-01

    Ülevaade The Times Literary Supplement 21. aug. 1998 artiklitest: George Orwelli Kogutud teostest (toim. Peter Davidson, kirj. Secker and Warburg) ja Gillian Fenwicki koostatud G. Orwelli bibliograafiast (New Castle : Oak Knoll Books). Ka G. Orwelli tõlkimisest eesti keelde

  1. The Dora Lange Archive

    Holm, Isak Winkel; Bjering, Jens Christian Borrebye

    2016-01-01

    The first season of Nic Pizzolatto's True Detective (2014) is not only a show about a murder, but also a show about how to gather and organize information in an archive. Having identified two archival problems—its temporal and topical extension—the article turns to Jacques Derrida's Archive Fever......: a Freudian Impression in order to explain how the archiving problems of the crime investigation are, in fact, intrinsic to any archiving practice. Lastly, the article addresses the political significance of the show's archiving problems by help of Derrida's text on the American Constitution and of Hardt...

  2. Arvustused / Aleks Lange

    Lange, Aleks

    2000-01-01

    Uute heliplaatide Nils Petter Molvaer "Solid Ether", Leona Naess "Comatised", Naivity in Black II "A Tribute to Black Sabbath", Papa Roach "Infest", A Perfect Circle "Mer de Noms", Queens of the Stone Age "Rated R", "Road Trip" (soundtrack) tutvustused

  3. Plaadid / Aleks Lange

    Lange, Aleks

    2003-01-01

    Uutest plaatidest Ricky Martin "Almas del Silencio", Paul McCartney "Back In Th e World", The Ultimate "Diva Collection", Girls Aloud "Sound Of The Underground", Blacky "Kui me päikeseloojangut ootama peaks", Christoph Poppen, Münchner Kammerorchester, The Hilliard Ensemble, Cerys Matthews "Cockahoop", Radiohead "Hail to the Thief"

  4. De lange weg

    Maas Geesteranus, R.A.

    1968-01-01

    Peziza alpina (Fuck.) Cooke (1876) and Peziza alpina (Fuck.) Oud. (1885) are recombinations based on Humaria alpina Fuck. (1874), and have no relation with Peziza alpina Sauter (1878). While the identity of Fuckel’s species is left out of consideration (as it will be discussed in a future paper),

  5. Langs Rembrandts roem

    Belien, Herman; Knevel, Paul

    2006-01-01

    The Dutch love Rembrandt. This year will see a celebration of the 400th anniversary of his birth, remembered with many festivities and much discussed, with many high profile exhibitions. Yet this homage is less obvious than many might think. Rembrandt only became famous after his death, thanks to

  6. Cornelia de Lange syndrome

    Boyle, M I; Jespersgaard, C; Brøndum-Nielsen, K

    2015-01-01

    , and hirsutism. Congenital anomalies include malformations of the upper limbs, gastrointestinal malformation/rotation, pyloric stenosis, diaphragmatic hernia, heart defects and genitourinary malformations. Gastroesophageal reflux disease is present in almost all patients. In addition to classic forms, milder...

  7. Costly cables; Lange Leitung

    Hautmann, Daniel

    2012-08-15

    Connection of offshore wind turbines to the onshore power supply grid requires costly cables for HV DC power transmission. The technology is mature enough to enable low-loss power transmission, but construction times may last several years.

  8. Smagsdommernes lange skygge

    Hermansen, Judy

    2009-01-01

    Den franske sociolog Pierre Bourdieu påstod, at smag er noget man tilegner sig gennem opdragelse og socialisering og derfor så dybt rodfæstet i personligheden, at den er meget vanskelig at ændre på. Denne opfattelse har været kritiseret af mange postmoderne trendforskere og symbolanalytikere, som...

  9. Giuseppe Castiglione (Lang Shining, precursor de la primera mundialización pictórico-arquitectónica

    Manuel V. Castilla

    2016-09-01

    Full Text Available La obra del hermano lego jesuita Giuseppe Castiglione (nombre chino, Lang Shining, 1688-1766, desarrollada en la China Qing, no fue suficientemente conocida sino hasta el siglo xx, y se ha investigado muy poco sobre su papel precursor de la primera mundialización artística. Su aproximación a China fue primordialmente de carácter apostólico, como consecuencia de la acción misional. Esta misión estuvo basada en un proceso inculturador fundamentado, a su vez, en el intercambio de las ciencias y las artes. Este artículo pone de manifiesto el riguroso conocimiento que sobre perspectiva matemática lineal había adquirido Castiglione en Europa, y la trascendencia que tuvo en la hibridación cultural y artística en la China del siglo xviii. Su posible repercusión en manifestaciones artísticas posteriores en otros territorios constituye el tema central del trabajo. Desde el punto de vista artístico, dada su privilegiada posición en la corte imperial, el artista jesuita jugó un papel decisivo en los nuevos métodos pictórico-arquitectónicos que se desarrollaron en la dinastía Qing. Sus murales, retratos, caballos, flores y pájaros, fueron elogiados y admirados por el emperador Qianlong, y mucho tiempo después por diseñadores y pintores europeos. Al simbolismo y la sensibilidad de la pintura asiática, Castiglione añadió el misterio del ilusionismo mágico que encierra la perspectiva matemática lineal europea, que contenía la llave y el secreto del conocimiento geométrico de Lang Shining. Sin embargo, sus efectos no fueron exclusivamente artísticos, sino que en muchos casos tuvieron una vigorosa dimensión apostólica. La dimensión religiosa que presuponemos en las pinturas de los artistas jesuitas fue una herramienta esencial en el proceso de inculturación; en este sentido, G. Castiglione usó la perspectiva no sólo como una técnica que gustaba a los emperadores, y fundamentalmente al emperador Qianlong, sino también como

  10. Plutonic rocks in the Mineoka-Setogawa ophiolitic mélange, central Japan: Fragments of middle to lower crust of the Izu-Bonin-Mariana Arc?

    Ichiyama, Yuji; Ito, Hisatoshi; Hokanishi, Natsumi; Tamura, Akihiro; Arai, Shoji

    2017-06-01

    A Paleogene accretionary complex, the Mineoka-Setogawa Belt, is distributed around the Izu Collision Zone, central Japan. Plutonic rocks of gabbro, diorite and tonalite compositions are included as fragments and dykes in an ophiolitic mélange in this belt. Zircon U-Pb dating of the plutonic rocks indicates that they were formed at ca. 35 Ma simultaneously. These ages are consistent with Eocene-Oligocene tholeiite and calc-alkaline arc magmatism in the Izu-Bonin-Mariana (IBM) Arc and exclude several previous models for the origin of the Mineoka-Setogawa ophiolitic rocks. The geochemical characteristics of these plutonic rocks are similar to those of the Eocene-Oligocene IBM tholeiite and calc-alkaline volcanic rocks as well as to the accreted middle crust of the IBM Arc, the Tanzawa Plutonic Complex. Moreover, their lithology is consistent with those of the middle and lower crust of the IBM Arc estimated from the seismic velocity structure. These lines of evidence strongly indicate that the plutonic rocks in the Mineoka-Setogawa ophiolitic mélange are fragments of the middle to lower crust of the IBM Arc. Additionally, the presence of the Mineoka-Setogawa intermediate to felsic plutonic rocks supports the hypothesis that intermediate magma can form continental crust in intra-oceanic arcs.

  11. Listwaenite in the Sartohay ophiolitic mélange (Xinjiang, China): A genetic model based on petrology, U-Pb chronology and trace element geochemistry

    Qiu, Tian; Zhu, Yongfeng

    2018-03-01

    Listwaenite lenses in the Sartohay ophiolitic mélange (Xinjiang, China) were formed via reactions between serpentinite and metasomatic fluids. First, serpentinite changed into talc schist via the reaction of serpentine + CO2 → talc + magnesite + H2O. Second, talc schist changed into listwaenite via the reaction of talc + CO2 → magnesite + quartz + H2O. Magnetite was progressively destroyed during transformation from serpentinite to talc schist, and completely consumed in listwaenite. Zircon crystals 30-100 μm long, disseminating in talc schist, undeformed listwaenite and mylonitized listwaenite, coexist with talc, quartz and magnesite, while micron-sized zircon grains (ages (302.9 ± 6.8 Ma, 299.7 ± 5.5 Ma and 296.5 ± 3.5 Ma), and are thought to represent the age of formation of the talc schist and listwaenite. These ages are indistinguishable within errors and suggest a rapid transformation from talc schist to listwaenite. Some zircon rims in samples of the undeformed listwaenite and mylonitized listwaenite give much younger apparent U-Pb ages (280-277 Ma), which could be interpreted as a recrystallization age reflecting late-stage shearing in the Sartohay ophiolitic mélange.

  12. Utilisation de mélanges non-azéotropiques dans les cycles thermodynamiques à compression Use of Non-Azeotropic Mixtures in Thermodynamic Compression Cycles

    Ambrosino J. L.

    2006-11-01

    Full Text Available L'utilisation de mélanges non-azéotropiques comme fluides frigorigènes présente différents avantages en ce qui concerne le fonctionnement des installations de réfrigération / conditionnement / chauffage mettant en oeuvre des cycles thermodynamiques à compression avec changement de phase. En outre, de tels mélanges représentent une alternative intéressante aux corps purs actuellement recherchés pour résoudre les problèmes d'environnement liés à la destruction de la couche d'ozone. Cet article analyse les connaissances acquises concernant la mise en oeuvre d'une telle solution. The use of non-azeotropic mixtures as refrigerants has various advantages concerning the operating of refrigeration / air-conditioning / heating installations implementing thermodynamic compression cycles with a phase change. Likewise, such mixtures represent an interesting alternative to pure components which are now being looked to as a solution to environmental problems linked to the destruction of the ozone layer. This article analyzes what is known about the implementation of such a solution.

  13. Keha võõras nahas ehk antropoloogiline eksperimentalism / Aet Annist

    Annist, Aet

    2009-01-01

    Eksperimentidest kunstis ja antropoloogias. Kristina Normani kunstiprojektist kuldse pronkssõduriga ja Ameerika valge ajakirjaniku John H. Griffini eksperimendist veeta kuus nädalat mustanahalisena USA lõunaosariikides

  14. The Travails of Criticality: Understanding Peter McLaren's Revolutionary Vocation. An Article Review of Peter McLaren, "Pedagogy of Insurrection" (New York: Peter Lang, 2015)

    Baldacchino, John

    2017-01-01

    This is an article review of Peter McLaren's "Pedagogy of Insurrection" (New York: Peter Lang, 2015). While it seeks to position McLaren's work within the context of critical pedagogy, this paper also assesses McLaren from the wider discussion of Marxist--Hegelian discourse as it evolved within the Left. Engaging with McLaren critically,…

  15. NOAA TIFF Image - Bathymetry - Lang bank, St. Croix, USVI - Benthic Habitat Characterization - NOAA Ship Nancy Foster - M-1907-NF-14 (2014), UTM 20N NAD83 (NCEI Accession 0128255)

    National Oceanic and Atmospheric Administration, Department of Commerce — This image represents a 1 meter resolution bathymetry of the reef shelf and the steep slopes of Lang Bank (H12639) of St. Croix, US Virgin Islands. The M-I907-NF-14...

  16. [Thomas Lange. Zwischen Reformation und Untergang Alt-Livlands : der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer] / Juhan Kreem

    Kreem, Juhan, 1971-

    2015-01-01

    Arvustus: Lange, Thomas. Zwischen Reformation und Untergang Alt-Livlands : der Rigaer Erzbischof Wilhelm von Brandenburg im Beziehungsgeflecht der livländischen Konföderation und ihrer Nachbarländer (Hamburger Beiträge zur Geschichte des östlichen Europa)

  17. A Comparison of Documentary Approaches: Margaret Bourke-White and Erskine Caldwell, Authors of "You Have Seen Their Faces," and Dorothea Lange and Paul S. Taylor, Authors of "An American Exodus."

    Hanson, Art

    Two books that use documentary photography to examine social problems--"You Have Seen Their Faces," a 1937 study of Southern sharecroppers by Margaret Bourke-White and Erskine Caldwell, and "An American Exodus," a 1939 examination of the migration of farm families by Dorothea Lange and Paul S. Taylor--are compared in this…

  18. i-gel: a new supraglottic device for effective resuscitation of a very low birthweight infant with Cornelia de Lange syndrome

    Galderisi, Alfonso; De Bernardo, Giuseppe; Lorenzon, Eleonora; Trevisanuto, Daniele

    2015-01-01

    Laryngeal Mask Airway (LMA) has been indicated as an effective device for airway management when face-mask ventilation and intubation have both failed in infants weighing >2000 g or delivered ≥34 weeks of gestation. All previous studies used a classic LMA. The current report describes the first case of a very low birthweight infant (1470 g, <3rd centile; 36+3gestational weeks) with micrognathia and palate cleft with Cornelia De Lange syndrome, resuscitated at birth with a new supraglottic airway device, i-gel size-1, positioned by a trainee paediatrician at first attempt. The procedure allowed reaching prompt effective ventilation and oxygenation of the patient, who was stabilised and intubated through i-gel. PMID:25809435

  19. Jervell and Lange-Nielsen syndrome in a father and daughter from a large highly inbred family: a 16-year follow-up of 59 living members.

    Sanyal, Shyamal Kumar; Kaul, Kanwar K; Hussein, Akhtar; Wilroy, Robert S; Agarwal, Kisan; Sohel, Saira

    2013-08-01

    To report the autosomal dominant inheritance of the Jervell and Lange-Nielsen syndrome in a highly inbred family, the initiation of Torsades de Pointes, and the natural history of the syndrome based on a 16-year follow-up of the kindred. A family tree was constructed that included 66 blood relatives from three successive generations. Electrocardiograms were obtained from 59 living members including the proband, four members from a nuclear family, and 54 from the extended family. Evoked response audiometry was recorded for the proband and the nuclear family. All 59 family members were followed up regularly for 16 years. A total of 24 living members were affected--QTc: 480-680 ms. The proband had long QTc, bilateral high-tone sensorineural deafness, recurrent syncope, and Torsades de Pointes. The asymptomatic father had long QTc and unilateral high-tone sensorineural deafness that involved specifically the left ear. One asymptomatic sibling of the proband had long QTc and normal hearing. The mother and another sibling were asymptomatic; QTc and hearing were normal in both. A total of 21 affected members from the extended family had only long QTc, and all were asymptomatic. There were three congenitally deaf first cousins who had recurrent syncope and adrenergic-triggered sudden death. In all, seven of 10 parents had consanguineous marriage to a first cousin. Each affected offspring had at least one affected parent. The severely symptomatic proband who received only β-blocker therapy and the 23 affected members without antiadrenergic therapy, all remained asymptomatic throughout the 16-year follow-up period. Jervell and Lange-Nielsen syndrome was inherited as autosomal dominant in this kindred. The majority of the affected members had a mild phenotype. The severity of auditory and cardiac phenotypes corresponded.

  20. Fluid inclusions in jadeitite and jadeite-rich rock from serpentinite mélanges in northern Hispaniola: Trapped ambient fluids in a cold subduction channel

    Kawamoto, Tatsuhiko; Hertwig, Andreas; Schertl, Hans-Peter; Maresch, Walter V.

    2018-05-01

    Freezing-point depression was measured in aqueous fluid inclusions to determine salinities in six samples of jadeitite and jadeite-rich rock from the Jagua Clara serpentinite mélange of the Rio San Juan Complex, Dominican Republic. The mélange represents a fossil subduction-zone channel from a cold, mature subduction zone with a geothermal gradient of 6 °C/km. One hundred and twenty-five determinations of salinity in primary inclusions hosted in jadeite, quartz, apatite and lawsonite range between extremes of 1.2 and 8.7, but yield a well-defined mean of 4.5 ± 1.1 wt% (±1 s.d.) NaCl equiv, slightly higher than mean seawater (3.5 wt%). In one sample, eight additional fluid inclusions in quartz aligned along grain boundaries yield slightly lower values of 2.7 ± 1.3 wt% NaCl equiv. Homogenization temperatures were also measured for 47 fluid inclusions in two samples, but primary entrapment densities are not preserved. It is significant that the suite includes two types of samples: those precipitated directly from an aqueous fluid as well as examples of metasomatic replacement of a pre-existing magmatic rock. Nevertheless, the results indicate identical salinity for both types and suggest a much stronger genetic link between the two types of jadeitite and jadeite-rich rock than has previously been assumed. Based on the results of conductivity measurements in modern subduction zones, we envision a pervasive fluid in the subduction channel that evolved from salinity levels lower than those in sea-water up to the measured values due to on-going but largely completed serpentinization in the subduction channel. The present data represent a reference marker for the subduction channel of the Rio San Juan intra-oceanic subduction zone at 30-50 km depth and after 50-60 Myr of operation.

  1. Destruksie ten minste tien maal beklemtoon – ’n interpretasie van 'Kraak die aardbol langs ’n naat' van Wilma Stockenström

    B. van der Westhuizen

    2002-08-01

    Full Text Available Destruction at least ten times emphasized – an interpretation of 'Kraak die aardbol langs ’n naat' ('Cracking the earth along the seam' by Wilma Stockenström In this article the value of syntactical analysis in the interpretation of a poem is investigated from the premise that emphasis can be effected inter alia in the following ways: (a by contravening certain rules that apply in standard language usage in order to compose grammatical sentences, b the exploitation of parallel syntactical structures, and c the relationship between sentence unit and line, and line and/or stanza. These theoretical points of departure form the basis of the syntactical analysis of “Kraak die aardbol langs ’n naat” (Wilma Stockenström, in which there are numerous deviations from the expected, normal and usual ways of constructing sentences. It is by these means that the semantic values gain prominence: the attention is drawn to the deviating behaviour of mankind continuing to destruct the earth until nothing remains. It is evident that the repeated use of irony and the satirical tone of this poem also contribute to persuade the reader to behave in a way opposite to that depicted in the poem. In this way the value of a syntactical analysis of this poem is illustrated. By uncovering the micro-structures (syntactical units within the (macro- structure (the poem, underlying patterns and the place of humanity in the universe can be better understood. In this way the analysis of this poem is then linked to the field of ecocriticism.

  2. Petrology and Geochemistry of Tethyan Mélange and Flysch Units Adjacent to the Yarlung Zangbo Suture Zone (YZSZ), Southern Tibet

    Dupuis, C.; Hebert, R.; Wang, C.; Li, Y.; Li, Z.

    2004-05-01

    Located north of the Himalayas, the E-W trending YZSZ is mainly composed of remnants of the Neo-Tethys ocean-floor and marks the suture between Indian and Eurasian plates. This project aims to define geological units immediately South of the YZSZ ophiolites : the serpentinized ophiolitic mélange, the Jurassic-Cretaceous wildflysch and the Triassic flysch. The ophiolitic mélange is characterized by ultramafic rocks, which can be divided into 3 groups. Cpx-harzburgites contain brownish aluminous spinels with Mg# of 0.7-0.75 and Cr# of 0.15-0.27. They resemble fertile abyssal peridotites with generally smooth LREE-depleted and fairly flat MREE-HREE profiles. Transitional harzburgites contain reddish spinels with Mg# of 0.57-0.66 and Cr# of 0.35-0.46. They resemble depleted abyssal or supra-subduction zone peridotites in that MREE-HREE profiles have positive slopes indicative of high degrees of partial melting. LREE profiles vary from depleted to slightly enriched, consistent with some trapped or interacting melt or aqueous fluids. Harzburgites and dunites contain dark reddish spinels with Mg# of 0.47-0.68 and Cr# of 0.40-0.63. They have U-shaped profiles characteristics of interaction between LREE-enriched melt and REE-depleted mantle residues. Spinel compositions and fractional melting modelling indicate that Cpx-harburgites may be the residues from 5-15% melting, transitional harzburgites from 15-23% melting, and harzburgites and dunites from 22-29% melting. The South Sandwich arc-basin system is considered a modern analog of initial geodynamic setting. Mafic rocks (gabbros, diabases and basalts) are ubiquitous and can be geochemically subdivided according to their source unit. LREE-depleted profiles with average (La/Yb)N of 0.5 and slight negative Nb-Ta and Ti anomalies indicate that rocks from the ophiolitic mélange formed in a back-arc basin, such as back-arc-basin mafic rocks of the Izu-Bonin Arc. REE patterns of rocks from the wildflysch are LREE

  3. Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in a mouse model of human Jervell and Lange-Nielsen deafness syndrome.

    Chang, Qing; Wang, Jianjun; Li, Qi; Kim, Yeunjung; Zhou, Binfei; Wang, Yunfeng; Li, Huawei; Lin, Xi

    2015-08-01

    Mutations in the potassium channel subunit KCNQ1 cause the human severe congenital deafness Jervell and Lange-Nielsen (JLN) syndrome. We applied a gene therapy approach in a mouse model of JLN syndrome (Kcnq1(-/-) mice) to prevent the development of deafness in the adult stage. A modified adeno-associated virus construct carrying a Kcnq1 expression cassette was injected postnatally (P0-P2) into the endolymph, which resulted in Kcnq1 expression in most cochlear marginal cells where native Kcnq1 is exclusively expressed. We also found that extensive ectopic virally mediated Kcnq1 transgene expression did not affect normal cochlear functions. Examination of cochlear morphology showed that the collapse of the Reissner's membrane and degeneration of hair cells (HCs) and cells in the spiral ganglia were corrected in Kcnq1(-/-) mice. Electrophysiological tests showed normal endocochlear potential in treated ears. In addition, auditory brainstem responses showed significant hearing preservation in the injected ears, ranging from 20 dB improvement to complete correction of the deafness phenotype. Our results demonstrate the first successful gene therapy treatment for gene defects specifically affecting the function of the stria vascularis, which is a major site affected by genetic mutations in inherited hearing loss. © 2015 The Authors. Published under the terms of the CC BY 4.0 license.

  4. A novel hybrid evidential belief function-based fuzzy logic model in spatial prediction of rainfall-induced shallow landslides in the Lang Son city area (Vietnam

    Dieu Tien Bui

    2015-04-01

    Full Text Available The main objective of this study is to investigate potential application of an integrated evidential belief function (EBF-based fuzzy logic model for spatial prediction of rainfall-induced shallow landslides in the Lang Son city area (Vietnam. First, a landslide inventory map was constructed from various sources. Then the landslide inventory map was randomly partitioned as a ratio of 70/30 for training and validation of the models, respectively. Second, six landslide conditioning factors (slope angle, slope aspect, lithology, distance to faults, soil type, land use were prepared and fuzzy membership values for these factors classes were estimated using the EBF. Subsequently, fuzzy operators were used to generate landslide susceptibility maps. Finally, the susceptibility maps were validated and compared using the validation dataset. The results show that the lowest prediction capability is the fuzzy SUM (76.6%. The prediction capability is almost the same for the fuzzy PRODUCT and fuzzy GAMMA models (79.6%. Compared to the frequency-ratio based fuzzy logic models, the EBF-based fuzzy logic models showed better result in both the success rate and prediction rate. The results from this study may be useful for local planner in areas prone to landslides. The modelling approach can be applied for other areas.

  5. Vigotski contra James-Lange: crítica para uma teoria histórico-cultural das emoções

    Gisele Toassa

    2012-03-01

    Full Text Available Ponderações sobre as emoções humanas apresentaram-se em toda a obra do bielorrusso L. S. Vigotski, desde sua juvenil crítica de arte. Nesse tópico, debateu a contribuição de vários autores: Freud, Claparède, Ribot, Lewin, Wundt. Entretanto, a perspectiva mais analisada por ele foi a teoria James-Lange. O objetivo deste artigo é discutir a extensa crítica que Vigotski dirigiu a ela no manuscrito “Utchenie ob Emotsiakh”, a qual se enquadrava numa ampla atitude teórico-metodológica do autor: a de compilar e relacionar o material fatual sem coordenação, expondo a luta de ideias filosóficas por detrás das psicológicas, de modo a abrir caminho para futuras investigações destinadas à superação do dualismo na psicologia. A partir dos principais fundamentos vigotskianos para futuros estudos, discutimos essa querela acerca das emoções, tema que o bielorrusso considerava a parte mais difícil e, possivelmente, a mais importante para o futuro da ciência psicológica.

  6. A rhinocerotid-dominated megafauna at the MIS6-5 transition: The late Middle Pleistocene Coc Muoi assemblage, Lang Son province, Vietnam

    Bacon, Anne-Marie; Antoine, Pierre-Olivier; Huong, Nguyen Thi Mai; Westaway, Kira; Tuan, Nguyen Anh; Duringer, Philippe; Zhao, Jian-xin; Ponche, Jean-Luc; Dung, Sam Canh; Nghia, Truong Huu; Minh, Tran Thi; Son, Pham Thanh; Boyon, Marc; Thuy, Nguyen Thi Kim; Blin, Amandine; Demeter, Fabrice

    2018-04-01

    Little is known about the ecosystems in the north of the Indochinese peninsula at the Middle-Late Pleistocene transition. In this paper, we analyzed the new fauna from Coc Muoi cave, Lang Son province, northeast Vietnam. In comparison with other well-documented faunas from the region, that of Coc Muoi is distinguished by the predominance of rhinoceroses among diverse large-bodied herbivores. The results of the OSL and pIR-IRSL dating of the cave sediments and U-series dating of flowstones indicate a potential age range of 148-117 ka for the fauna (MIS6-5). The analysis of age-at-death distributions of rhinoceroses, wild cattle, sambar deer, and wild pig, does not show any apparent selectivity of age classes. We also focused our study on rhinoceroses, tapirs, and wild cattle by analyzing the prevalence of hypoplastic defects on deciduous and permanent teeth, in an attempt to assess the health status of the taxa during their first years of growth. The health status of large-bodied herbivores (kouprey and rhinoceros) reveals the importance of stressors (biotic and abiotic) in the rainforest environment during a period of marked climatic transition (MIS6-5) in comparison with other MIS5-4 well-documented faunas from the region.

  7. Bill Lang's contributions to acoustics at International Business Machines Corporation (IBM), signal processing, international standards, and professionalism in noise control engineering

    Maling, George C.

    2005-09-01

    Bill Lang joined IBM in the late 1950s with a mandate from Thomas Watson Jr. himself to establish an acoustics program at IBM. Bill created the facilities in Poughkeepsie, developed the local program, and was the leader in having other IBM locations with development and manufacturing responsibilities construct facilities and hire staff under the Interdivisional Liaison Program. He also directed IBMs acoustics technology program. In the mid-1960s, he led an IEEE standards group in Audio and Electroacoustics, and, with the help of James Cooley, Peter Welch, and others, introduced the fast Fourier transform to the acoustics community. He was the convenor of ISO TC 43 SC1 WG6 that began writing the 3740 series of standards in the 1970s. It was his suggestion to promote professionalism in noise control engineering, and, through meetings with Leo Beranek and others, led the founding of INCE/USA in 1971. He was also a leader of the team that founded International INCE in 1974, and he served as president from 1988 until 1999.

  8. Environmental monitoring program for the Ormen Lange Onshore Processing Plant and the Reserve Power Plant at Nyhamna, Gossa. Monitoring of vegetation and soil: re-analyses and establishment of new monitoring plots in 2010.; Miljoeovervaakingsprogram for Ormen Lange landanlegg og Reservegasskraftverk paa Nyhamna, Gossa. Overvaaking av vegetasjon og jord: gjenanalyser og nyetablering av overvaakingsfelter i 2010

    Aarrestad, P.A.; Bakkestuen, V.; Stabbetorp, O.E.; Myklebost, Heidi

    2011-07-01

    The Ormen Lange Onshore Processing Plant in Aukra municipality (Moere og Romsdal county) receives unprocessed gas and condensate from the Ormen Lange field in the Norwegian Sea. During processing of sales gas and condensate, the plant emits CO, Co2, Nox, CH4, NMVOC (including BTEX), SO2 and small amounts of heavy metals, as specified in the discharge permit issued by the Climate and Pollution Directorate. The plant started production in 2007, with A/S Norske Shell as operator. In general, emissions of nitrogen and sulphur-containing gasses may affect terrestrial ecosystems through acidification and fertilization of soil and vegetation. The emissions from the onshore plant are calculated to be below the current critical loads for the terrestrial nature types. However, the nitrogen background level in the area of influence is close to the critical loads for oligotrophic habitats. To be able to document any effects of emissions to air on terrestrial ecosystems, a monitoring program for vegetation and soil was established in 2008 in the area of influence from the Ormen Lange Onshore Plant. The monitoring is planned at regular intervals according to the same methods employed in 2008, with the first reanalysis in 2010. The benefits of the monitoring parameters will be continuously evaluated. Statnett has established a Reserve Power Plant with discharge permits of similar substances in the same area as the Ormen Lange Onshore Processing plant, and participates in an extended monitor program from 2010. In 2008 two monitoring sites were established, one with rather high deposition of nitrogen north of the plant within Gule-Stavmyran nature reserve in Fraena municipality (site Gulmyran) and one south of the plant on the island Gossa (site Aukra). Deposition values have been estimated by the Norwegian Institute for Air Research (NILU). Within each site integrated monitoring of the species composition of the vegetation, plant growth, and chemical content of plants and soil is

  9. Crescimento de Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae sob diferentes níveis de sombreamento Growth of Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae under different shading levels

    Ana Lúcia da Silva Lima

    2010-03-01

    Full Text Available Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. é uma espécie clímax tolerante a sombra, ao passo que Enterolobium contortisiliquum (Vell. Morong. é uma espécie pioneira. O desenvolvimento destas espécies pode refletir a habilidade de adaptação aos diferentes fatores ambientais (luz, água e temperatura no local em que estão crescendo. O suprimento inadequado de um desses fatores pode reduzir o vigor da planta e limitar seu desenvolvimento. O presente trabalho teve como objetivo avaliar os efeitos do nível de sombreamento no crescimento e a concentração de pigmentos fotossintéticos em duas espécies de leguminosas arbóreas, Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong. O experimento foi conduzido no Setor de Olericultura do Centro Universitário Luterano de Ji-Paraná (CEULJI/ULBRA/Rondônia. Durante a formação das mudas, ambas as espécies foram expostas a quatro tratamentos de sombra: 0 % (controle - sol pleno; 30 %; 50 % e 80 %. Cada tratamento foi constituído com três repetições de cada espécie; o delineamento experimental foi inteiramente casualisado. Quatro meses após a semeadura, as seguintes análises foram realizadas: número de folhas, altura da planta, comprimento do sistema radicular, massa seca total e concentração de pigmentos fotossintéticos. O tratamento sob sol pleno afetou negativamente o crescimento de ambas as espécies. As mudas crescidas sob 50% e 80% apresentaram melhor desenvolvimento. Conforme o aumento do sombreamento houve um decréscimo na razão clorofila a/b e um aumento nas concentrações de clorofila total e carotenóides totais.Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. is a clímax shadow tolerant specie and Enterolobium contortisiliquum (Vell. Morong., by the other hand, is considered as a pioneer specie. The development of these species may reflect its adaptation ability to different environmental

  10. Blueschist metamorphism and its tectonic implication of Late Paleozoic-Early Mesozoic metabasites in the mélange zones, central Inner Mongolia, China

    Zhang, Jinrui; Wei, Chunjing; Chu, Hang

    2015-01-01

    Blueschists in central Inner Mongolia are distributed as layers and blocks in mélanges including the southern zone in Ondor Sum area and the northern zone in Manghete and Naomuhunni areas. They have been attributed to the subduction of Early Paleozoic oceanic crust. Blueschists from Ondor Sum and Naomuhunni are characterized by occurrence of sodic amphibole coexisting with epidote, albite, chlorite, calcic amphibole (in Ondor Sum) and muscovite (in Naomuhunni). Blueschists in Manghete contain porphyroblastic albite with inclusions of garnet and epidote in a matrix dominated by calcic-sodic amphibole, epidote, chlorite, albite and muscovite. Phase equilibria modeling for three blueschist samples using pseudosection suggest that the AlM2 contents in sodic amphibole can be used as a good barometer in the limited assemblage involving sodic amphibole + actinolite + epidote + chlorite + albite + quartz under pressures 7-10 kbar. In the sodic amphibole-bearing assemblages, the NaM4 contents in sodic amphibole mainly decrease as temperature rises, being a potential thermometry. The calculated pseudosections constrain the P-T conditions of blueschists to be 3.2-4.2 kbar/355-415 °C in Ondor Sum, 8.2-9.0 kbar/455 °C-495 °C in Manghete and 6.6-8.1 kbar/420-470 °C in Naomuhunni. These P-T estimates indicate a rather high geothermal gradient of 18-25 °C/km for the blueschist metamorphism, being of intermediate P/T facies series. Available zircon U-Pb age data suggests that the protoliths of blueschists were formed later than Late Paleozoic-Early Mesozoic and metamorphosed soon afterwards. An alternative interpretation for the tectonic implication of blueschists in central Inner Mongolia is that they may be a new type attributed to closure of limited ocean basins and do not represent a tectonic regime occurred in conventional subduction setting.

  11. Patterns of HIV prevalence among injecting drug users in the cross-border area of Lang Son Province, Vietnam, and Ning Ming County, Guangxi Province, China

    Hoang Tran V

    2005-08-01

    Full Text Available Abstract Background To assess patterns of injecting drug use and HIV prevalence among injecting drug users (IDUs in an international border area along a major heroin trans-shipment route. Methods Cross-sectional surveys of IDUs in 5 sites in Lang Son Province, Vietnam (n = 348 and 3 sites in Ning Ming County, Guangxi Province, China (n = 308. Respondents were recruited through peer referral ("snowball" methods in both countries, and also from officially recorded lists of IDUs in Vietnam. A risk behavior questionnaire was administered and HIV counseling and testing conducted. Results Participants in both countries were largely male, in their 20s, and unmarried. A majority of subjects in both countries were members of ethnic minority groups. There were strong geographic gradients for length of drug injecting and for HIV seroprevalence. Both mean years injecting and HIV seroprevalence declined from the Vietnamese site farthest from the border to the Chinese site farthest from the border. 10.6% of participants in China and 24.5% of participants in Vietnam reported crossing the international border in the 6 months prior to interview. Crossing the border by IDUs was associated with (1 distance from the border, (2 being a member of an ethnic minority group, and (3 being HIV seropositive among Chinese participants. Conclusion Reducing the international spread of HIV among IDUs will require programs at the global, regional, national, and "local cross border" levels. At the local cross border level, the programs should be coordinated on both sides of the border and on a sufficient scale that IDUs will be able to readily obtain clean injection equipment on the other side of the border as well as in their country of residence.

  12. Screening of Long Q-T Syndrome in Patients with Congenital Sensorineural Hearing Loss (Jervell and Lange Neilesen Syndrome: Prevention of Fatal Events

    Farid Matin

    2001-01-01

    Full Text Available Objective:The idiopathic long Q-T syndrome is an infrequently occurring disorder in which affected individuals have an unusual electrocardiographic repolarization abnormality presenting as syncope or loss of consciousness related to ventricular tachycardia or fibrillation. Congenital long Q-T prolongation can be associated with congenital deafness in an autosomal recessive manner (Jervell and Lange-Nielsen syndrome. The purpose of this stuff was to screen this electrocardiographic abnormality in deaf-mute school children in our population, which has not been yet performed. Materials & Methods:  Of 1190 patients with hearing loss, 779 had congenital sensorineural deafness (CSD, aged 13±3.8 years (4-24, 63% female and 37% male. The family history of deafness was as follows: Cardiac axis deviation was found in 56 (7% patients. Electrical conduction abnormalities were found in 12 (15% patients, Wolff-Parkinson-White syndrome, sinus bradycardia, and sinus arrhythmia were found in 2 (0.25%, 4 (0.5%, and 3 (0.38% patients, respectively. The Q-T interval, and Q-Tc duration were 312.6±28.9 ms (200-500 ms, median 320 ms, and 383.6±29.3 ms (232-527 ms, median 413ms, respectively. Long Q-T syndrome was found in 4 (0.5% patients (3F and 1M. Results: Two of these 4 patients had total deafness and 2 had profound hearing loss. None of the patients with mild deafness had Q-T prolongation. Only one of these patients was symptomatic, and had been treated as a case of epilepsy for several years. Conclusion: This data supports the presence of long Q-T syndrome in patients with sensorineural hearing loss in our population, so routine electrocardiographic screening of anyone with congenital deafness is warranted to prevent subsequent associated cardiac arrhythmias and sudden cardiac death.

  13. Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.

    Zhang, Miao; D'Aniello, Cristina; Verkerk, Arie O; Wrobel, Eva; Frank, Stefan; Ward-van Oostwaard, Dorien; Piccini, Ilaria; Freund, Christian; Rao, Jyoti; Seebohm, Guiscard; Atsma, Douwe E; Schulze-Bahr, Eric; Mummery, Christine L; Greber, Boris; Bellin, Milena

    2014-12-16

    Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening cardiac arrhythmias. Patients display delayed cardiac repolarization, associated high risk of sudden death due to ventricular tachycardia, and congenital bilateral deafness. In contrast to the autosomal dominant forms of long QT syndrome, JLNS is a recessive trait, resulting from homozygous (or compound heterozygous) mutations in KCNQ1 or KCNE1. These genes encode the α and β subunits, respectively, of the ion channel conducting the slow component of the delayed rectifier K(+) current, IKs. We used complementary approaches, reprogramming patient cells and genetic engineering, to generate human induced pluripotent stem cell (hiPSC) models of JLNS, covering splice site (c.478-2A>T) and missense (c.1781G>A) mutations, the two major classes of JLNS-causing defects in KCNQ1. Electrophysiological comparison of hiPSC-derived cardiomyocytes (CMs) from homozygous JLNS, heterozygous, and wild-type lines recapitulated the typical and severe features of JLNS, including pronounced action and field potential prolongation and severe reduction or absence of IKs. We show that this phenotype had distinct underlying molecular mechanisms in the two sets of cell lines: the previously unidentified c.478-2A>T mutation was amorphic and gave rise to a strictly recessive phenotype in JLNS-CMs, whereas the missense c.1781G>A lesion caused a gene dosage-dependent channel reduction at the cell membrane. Moreover, adrenergic stimulation caused action potential prolongation specifically in JLNS-CMs. Furthermore, sensitivity to proarrhythmic drugs was strongly enhanced in JLNS-CMs but could be pharmacologically corrected. Our data provide mechanistic insight into distinct classes of JLNS-causing mutations and demonstrate the potential of hiPSC-CMs in drug evaluation.

  14. The Jervell and Lange-Nielsen syndrome; atrial pacing combined with ß-blocker therapy, a favorable approach in young high-risk patients with long QT syndrome?

    Früh, Andreas; Siem, Geir; Holmström, Henrik; Døhlen, Gaute; Haugaa, Kristina H

    2016-11-01

    Patients with Jervell and Lange-Nielsen syndrome (JLNS) exhibit severe phenotypes that are characterized by congenital deafness, very long QT intervals, and high risk of life-threatening arrhythmias. Current treatment strategies include high doses of beta-blocker medication, left cardiac sympathetic denervation, and ICD placement, which is challenging in young children. The purpose of this study was to evaluate the safety and effect of pacing in addition to beta-blocker treatment in children with JLNS. All genetically confirmed patients with JLNS born since 1999 in Norway were included in the study. Data on history of long QT syndrome-related symptoms, QT interval, and beta-blocker and pacemaker treatment were recorded. A total of 9 patients with QT intervals ranging from 510 to 660 ms were identified. Eight patients developed long QT syndrome-related symptoms, and 1 patient died before diagnosis. The survivors received beta-blocker medication. Seven patients also received a pacemaker; 1 had a ventricular lead and 6 had atrial leads. The patient with the ventricular lead died during follow-up. The 6 patients with atrial leads survived without events at a mean follow-up of 6.9 years after pacemaker implantation. Two patients received prophylactic upgrade to a 2-chamber ICD. No arrhythmic events occurred in 6 very young JLNS patients who received atrial pacing in combination with increased doses of beta-blockers during 7-year follow-up. If confirmed in additional patients, this treatment strategy may prevent life-threatening arrhythmias in this high-risk patient group and may act as a bridge to insertion of a 2-chamber ICD when left cardiac sympathetic denervation is not available. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  15. L'auto adaptation à des mélanges essence/alcool utilisés comme carburant automobile: le moteur souple The Self-Adapting of Gasoline/Alcohol Mixtures Used As Automotive Fuel: the Flexible Engine

    Dorbon M.

    2006-11-01

    Full Text Available Le moteur souple est un moteur susceptible d'être alimenté par des carburants constitués de mélanges d'une essence classique et d'un alcool léger (méthanol ou éthanol; si la concentration de chacun des composants de ces mélanges varie, les réglages nécessaires au bon fonctionnement du véhicule se font automatiquement. Dans cet article, sont tout d'abord exposées les propriétés caractéristiques en tant que carburant automobile de l'un de ces alcools légers, le méthanol. Puis viennent les descriptions des dispositifs qui font le moteur souple c'est-à-dire d'une part les systèmes de reconnaissance du carburant et d'autre part les appareillages susceptibles de modifier les réglages du moteur (alimentation et allumage en fonction de la qualité du mélange consommé. A flexible engine is one capable of running on fuels consisting of mixtures of conventional gasoline and a light alcohol (methanol or ethanol. If the concentration of each of these components of such mixtures varies, the tuning required for the proper running of the vehicle takes place automatically. This article begins by describing the characteristic properties of one of these light alcohols (methanol as an automotive fuel. Then the equipment is described that makes an engine flexible, i. e. both the fuel recognition systems and the equipment capable of changing engine tuning (feed and ignition as a function of the quality of the mixture burned.

  16. Lang Lang: From child prodigy to Carregie Hall

    Tricia Carswell

    2004-01-01

    <正>As a child, I had three wishes: to have my own bicycle, to take figure-skating lessons, and to play piano. As a young mother of 26,I finally bought a bicycle which I happily rode up and down our farm laneway. At 34, my first lesson with a professional skating teacher was also my last when I fell on the ice and popped an instant bump the size of an egg on the back of my head. To my chagrin, the only keyboard I ever mastered was that of the typewriter/computer.

  17. Evaluation of Butanol–Gasoline Blends in a Port Fuel-injection, Spark-Ignition Engine Évaluation de mélange butanol-essence dans un moteur à allumage commandé à injection indirecte

    Dernotte J.

    2009-11-01

    Full Text Available This paper assesses different butanol–gasoline blends used in a port fuel-injection, spark-ignition engine to quantify the influence of butanol addition on the emission of unburned hydrocarbons, carbon monoxide, and nitrogen oxide. Furthermore, in-cylinder pressure was measured to quantify combustion stability and to compare the ignition delay and fully developed turbulent combustion phases as given by 0%–10% and 10%–90% Mass Fraction Burned (MFB. The main findings are: 1 a 40% butanol/60% gasoline blend by volume (B40 minimizes HC emissions; 2 no significant change in NOx emissions were observed, with the exception of the 80% butanol/20% gasoline blend; 3 the addition of butanol improves combustion stability as measured by the COV of IMEP; 4 butanol added to gasoline reduces ignition delay (0%–10% MFB; and 5 the specific fuel consumption of B40 blend is within 10% of that of pure gasoline for stoichiometric mixture. Cet article évalue le potentiel de l’utilisation de différents mélanges butanolessence dans un moteur à allumage commandé à injection indirecte afin de quantifier l’influence de l’ajout de butanol sur les émissions des hydrocarbures imbrûlés (HC, le monoxyde de carbone (CO et les oxydes d’azote (NOx. De plus, l’influence sur la stabilité de combustion, le délai d’inflammation et sur la durée de la phase de combustion turbulente développée y sont également présentés. Les principaux résultats: 1 un mélange de 40% butanol et 60% essence (B40 par volume diminue les émissions de HC; 2 aucun effet significatif sur les émissions de NOx n’a été observé à l’exception du mélange 80% butanol/20% essence; 3 l’ajout de butanol améliore la stabilité de combustion ; 4 l’ajout de butanol réduit le délai d’inflammation, quantifié par la durée pour consommer 10% de masse de gaz frais; et 5 la consommation spécifique de carburant pour un mélange stoechiométrique de B40 est 10% sup

  18. Geochronology and geochemistry of the Niujuanzi ophiolitic mélange, Gansu Province, NW China: implications for tectonic evolution of the Beishan Orogenic Collage

    Wang, Shengdong; Zhang, Kexin; Song, Bowen; Li, Shucai; Li, Ming; Zhou, Jie

    2018-01-01

    The Niujuanzi ophiolitic mélange (NOM), located in the Beishan Orogenic Collage, marks the termination between the Huaniushan arc and Mingshui-Hanshan Massifs. The NOM is mainly composed of gabbros, diabases, plagiogranites, basalts, and greywacke. Two gabbros have ages of 433.8 ± 3.1 and 354.0 ± 3.3 Ma, two plagiogranites have ages of 429.8 ± 2 and 448.7 ± 2.0 Ma, and a diabase has an age of 433.4 ± 3.2 Ma. The gabbros and diabases are calc-alkaline and tholeiitic, with high Al2O3, CaO, and TiO2 contents and low FeOT contents. The gabbros have high Mg# values (49-82), while the diabases have relatively low Mg# values (46-61). The plagiogranites are calc-alkaline and metaluminous, with high SiO2 and Na2O contents and low Al2O3 and K2O contents. The gabbros and diabases are enriched in large iron lithophile elements and slightly depleted in high field strength elements relative to N-MORB and their trace element characteristics are similar to E-MORB. With respect to rare earth element (REE), they have slightly enriched LREEs relative to HREEs. The majority of the plagiogranite trace elements approximate those of the volcanic arc granite. The plagiogranites have obviously enriched LREEs relative to HREEs, with a slightly to strongly negative Eu anomaly, which is similar to ORG but distinct from volcanic arc and within plate granite. The NOM was formed from the Ordovician to the Carboniferous, representing the expansion period of the Niujuanzi Ocean. The gabbros, diabases, and plagiogranites were formed in a mid-ocean ridge environment. The gabbros and diabases were generated by different degrees of partial melting of the mantle, and the plagiogranites derived from both the crystallization differentiation of basaltic magma and the partial melting of amphibolites in the crust.

  19. Séparation des mélanges eau-alcool à l'aide du CO2 supercritique : application au mélange éthanol eau Separation of Water-Alcohol Mixtures by Supercritical CO2: Application of the Ethanol- Water Mixture

    Fogel W.

    2006-11-01

    Full Text Available Les marchés accessibles à la technique d'extraction supercritique utilisant le CO2 seront plutôt orientés vers les alcools dérivés de la pétrochimie (isopropanol, butanol secondaire ou du gaz de synthèse (mélange d'alcools allant de l'éthanol à l'hexanol que vers les produits issus des fermentations pour lesquels la sélectivité de la séparation est théoriquement insuffisante et la concentration en alcool dans le moût fermenté trop faible. Markets for the supercritical extraction technique using CO2 will mainly be aimed for alcohols derived from petrochemicals (isopropanol, secondary butanol or from synthetic gas (mixture of alcohols ranging from ethanol to hexanol rather than for products from fermentations for which separation selectivity is theoretically insufficient and the alcohol concentration in the wort much too weak.

  20. Wallenbergide Investor jätkab kasvustrateegiat / Olev Mait Makk

    Makk, Olev Mait

    2001-01-01

    Wallenbergide kontrollitavast Rootsi investeerimisfirmast Investor, mille omanduses olevad firmad moodustavad kokku Euroopa suurima tööandja erasektoris. Investori gruppi kuuluvast ettevõttest SEB. Tabel: Investori portfellis olevad aktsiad; investori teenused tütarettevõtetele

  1. Põhjamaade põlisvähemuste omakeelsest meediast / Mait Talts

    Talts Mait, 1964-

    2009-01-01

    Artikkel jätkab Läänemere-äärsete etniliste vähemuskultuuride käsitlust. Vt. ka Haridus 5/6 2008, "Põlisvähemuskultuuride meediamaastikult" (latgalite, liivlaste, karaiimide, väikeleedulaste, kašuubide jt. omakeelse meedia hetkeolukorrast ja arenguperspektiividest)

  2. The singing revolution : part II-III / Mait Ando Raun

    Raun, Mait, 1963-

    2000-01-01

    Tartu rahu ja vabariigi aastapäeva tähistamisest 1988. aastal; Sündmused veebruarist aprillini 1988: üliõpilaste demonstratsioonist veebruaris, Loominguliste Liitude ühispleenumist, Rahvarinde loomisest ja Tartu muinsuskaitsepäevadest aprillis. Järg nr.4, lk.70-73

  3. Plaadid / Mait Eelrand, Toomas Puna, Veiko Pesur...[jt.

    2007-01-01

    Uutest heliplaatidest Wolf & Cub "Vessels", Karl MAdis & Karavan "Taevalik meloodia ئ Nat King Cole'i laule", Sophie Ellis-Bextor "Trip The Light Fantastic", Him "Uneasy Listening 1&2", Kognito "Muutuv"

  4. Finskii grafitsheskii beton teper takzhe i v Estonii / Mait Eelrand

    Eelrand, Mait

    2007-01-01

    Graafilise betooni meetodi arendas 1990. aastate lõpul välja soome sisearhitekt Samuli Naamanka, tehnoloogia on patenteerinud tema asutatud firma Graphic Concrete Oy. AS E-Betoonelement kasutas graafilise betooni tehnoloogiat esimesena Rakveres büroohoone fassaadi kujundamiseks. Kommenteerivad Graphic Concrete Oy tegevdirektor H. Lanningu ja K. Meus AS-st E-Betoonelement

  5. Teadusmõtte ja teaduse mineviku lood / Mait Talts

    Talts, Mait, 1964-

    2011-01-01

    Arvustus: Baltic Journal of European Studies. Selected papers of the 24th International Baltic Conference on the history of science and the follow-up seminar (2011, nr. 1). Tallinn : Tallinn University of Technology, 2011

  6. Rotermanni soolalao urbanistliku pargi ideekonkurss / Mait Väljas

    Väljas, Mait

    2009-01-01

    Eesti Arhitektuurimuuseumi korraldatud avalikust konkursist, Ignar Fjuki koostatud võistlustingimustest, premeeritud töödest. 1. preemia sai töö "Piazza", autor Villem Tomiste, (AB Kosmos)), 2. preemia töö "Muesuum", autor Ott Kadarik, (AB Kosmos), 3. preemia töö "Arhitektuuri allee", autor Jürgen Lepper, (AB Dimensioon). Anti välja üks ergutuspreemia, ära märgiti kaks tööd

  7. Arhitektuurivõistlused 2008 / Mait Väljas

    Väljas, Mait

    2008-01-01

    Võistluste tulemused: Pekingi saatkonnahoone: I preemia - A. Põime, L. Põime, L. Vaimel; Riia saatkonnahoone: I - L.-K. Stöör, Ü.-T. Stöör, H. Urb; Eesti Kunstiakadeemia uus õppehoone: I - SEA + Effekt (Taani); Eesti Maaülikooli Kreutzwaldi 5 õppehoone juurdeehitis: I - P. Loo, J. Skolimowski, L. Vene, K. Kruuse (KAMP Arhitektid); TÜ Viljandi Kultuuriakadeemia loomeinkubaatori ja lavakunstide õppehoone: I - S. Vallner, H. Urb, I. Peil, H. Lass, S.-M. Mändmaa (Kavakava); Tamula järve ranna-ala mahuline planeering: I - K. Enno, L. Luhse, M. Zeleznova, R. Ailt (K. Enno Arhitektuuribüroo); Tartu pärmivabriku kvartali arhitektuurivõistlus: võidutöö - Atelier Thomas Pucher / Bramberger Architects (Austria); Paldiski mnt. 50 kinnistu ja lähiala: I-II - T. Laigu, K. Ojaliiv, M. Rass, A. Uukado (QP Arhitektid); maastikuarhitektuuri võistlus "Eesti Maaülikooli Tähtvere linnaku välialad": I - H. Runnel, T. Ong; Tartu rahu tähisala kujundus: I - M. Kinks, K. Süda; Veneetsia XI rahvusvahelise arhitektuuribiennaali ideekavandi võistlus: I - M. Kask, R. Lõoke, N. Külm; aasta betoonehitis 2007 - Puurmani kaarsild, konstruktorid S. Idnurm, J. Idnurm; Eesti parim puitehitis 2008: eramu Loobul - R. Vaiksoo; võistluse "Eramu 2006-2007" peapreemia: villa Paldiskis - S. Vallner, I. Peil

  8. Katse portreteerida nõukogude kosmosemaja / Mait Väljas

    Väljas, Mait

    2011-01-01

    Prantsuse fotograafist Frédéric Chaubinist, kes pildistas NSV Liidus 1975.-1990. a. ehitatud eripäraseid hooneid, korraldas fotonäitusi. F. Chaubini raamatust "СССР : cosmic communist constructions photographed" (Köln : Taschen, 2011), raamatusse jõudnud eesti arhitektuurist

  9. Ma olen Turist, ma elan siin / Mait Väljas

    Väljas, Mait

    2006-01-01

    Endise valuutapoe, praeguse klubi "Parlament" lammutamisplaanist Tallinnas Tartu mnt. 17. Arhitektid Peep Jänes ja Henno Sepmann, sisearhitekt Toivo Gans, sisekujundaja Aulo Padar. Ehitamisel osalesid ka soome arhitektid Kalle-Heiki Narinen ja Tapio Hänninen. Kommentaar Peep Jäneselt ja Aulo Padarilt

  10. Herbert Johansoni eeskujulikud koolimajad / Mait Väljas

    Väljas, Mait

    2010-01-01

    Eesti arhitektuurimuuseumis eksponeeritava Herbert Johansoni (1884–1964) ja Eugen Habermanni (1884–1944) juubelinäituse taustal on kohane rääkida koolimajadest. Johansoni kontol on suur osa Tallinna sõdadevahelistest koolimajadest, kaks lasteaeda ja üks kutsekool

  11. From Ekofisk to Ormen Lange

    Wiborg, Rolf

    2005-01-01

    The oil industry on Norwegian continental shelf has existed for 35 years. An overview of the resource picture, the development of technologies and risk reduction is provided. Key achievements of the industry are presented. New requirements and new frontiers are outlined, and different scenarios for the future of the Norwegian continental shelf are presented (ml)

  12. From Ekofisk to Ormen Lange

    Wiborg, Rolf

    2005-03-15

    The oil industry on Norwegian continental shelf has existed for 35 years. An overview of the resource picture, the development of technologies and risk reduction is provided. Key achievements of the industry are presented. New requirements and new frontiers are outlined, and different scenarios for the future of the Norwegian continental shelf are presented (ml)

  13. narrative xml:lang="fr"

    The aim is to inform more effective violence prevention strategies that address ..... and violence by exploring how they provoke, sustain, and/or reduce these ...... the IDRC Corporate Strategy 2016-2020 and future programming areas of focus.

  14. narrative xml:lang="fr"

    Le secteur des petites et moyennes entreprises (PME) représente près de 60 % du produit .... Pour être en mesure d'exercer une influence sur les politiques, ..... sur sa mise en oeuvre de la stratégie d'évaluation 2005-2010 qui mettra l'accent ...... le plan d'activités de même que la stratégie de recrutement et de promotion.

  15. Milton Eestis, 1895 / Anne Lange

    Lange, Anne, 1962-

    2015-01-01

    Timotheos Kuusiku Miltoni poeemide "Paradise lost" ja "Paradise regained" tõlgetest - uuritakse teose retseptsiooni, tekstide kättesaadavust ja Kuusiku omakirjutusi, kõrvutatakse tõlget võimalike algvariantidega ning tutvustatakse tõlkijat ja ajaloolist konteksti

  16. Iseolemise uus paradigma / Rein Lang

    Lang, Rein, 1957-

    2004-01-01

    Oma essees nimetab autor 1992. aasta põhiseaduse neli kontseptuaalset eesmärki ning leiab, et neli peamist ülesannet, mis sellele põhiseadusele esitati, on enamjaolt täidetud, vaja on aga minna edasi. Meil tuleb mõtestada oma sõnum EL-is ja oma tahtmised järgmiseks iseolemise etapiks, ütleb autor kokkuvõtteks

  17. narrative xml:lang="fr"

    The aim is threefold: to enhance the ability of rural communities to manage their ...... point des interventions communautaires afin de cibler les habitats des larves qui ...... But, while there is a rich literature exploring the impact of decentralization on ...... and high mortality in domestic poultry, waterfowl and other bird species.

  18. Kalevite kange rahvas / Valter Lang

    Lang, Valter, 1958-

    2012-01-01

    Autor uurib, kuidas võidi kutsuda sotsiaalselt paremal järjel olevaid inimesi muinasajal, juhtides tähelepanu ühele võimalusele omakeelse ülikunime väljaselgitamisel - selleks võiks olla meie rahvaluule vägilane Kalev. Pöördutakse nii rahvaluule, keeleajaloo kui ka arheoloogia poole

  19. Lang, S. K. W. and Gardiner, B. D. (2014). "As They Like It--Culture-Centred Counsellor Education in the Context of Aotearoa New Zealand: A Play on Bicultural Pluralism." "British Journal of Guidance and Counselling", 42 (1), 73-85. doi.org./10.1080/03069885.2013.824949

    Au Yeung, Helen

    2016-01-01

    In their article, Lang and Gardiner draw support from the Treaty of Waitangi to deconstruct cultural dominance and reconstruct a framework, which promotes bicultural pluralism in the new counsellor education programme at the Massey University. However, they omit significant details of the Treaty and therefore mislead the audience to think that the…

  20. Paweł Bąk, Die Metapher in der Übersetzung. Studien zum Transfer der Aphorismen von Stanisław Jerzy Lec und der Gedichte von Wisława Szymborska, Peter Lang Europäischer Verlag der Wissenschaft en, Frankfurt am Main u. a. 2007 =...

    Zieliński, Lech

    2008-01-01

    Paweł Bąk, Die Metapher in der Ubersetzung. Studien zum Transfer der Aphorismen von Stanisław Jerzy Lec und der Gedichte von Wisława Szymborska, Peter Lang Europaischer Verlag der Wissenschaft en, Frankfurt am Main u. a. 2007 = Danziger Beitrage zur Germanistik, Bd. 20 wyd. Andrzej Kątny, 332 strony

  1. The importance of deciduous forest for alkalinity, phosphorus burial and isoetid macrophytes as revealed by a recent paleo study in a soft water Lobelia Lake (Grane Langsø, Denmark)

    Klamt, Anna-Marie; Reitzel, Kasper; Mortensen, Morten F.

    Lake Grane Langsø is characterized by nutrient-poor soft water with very high visibilities and hence contains rare isoetid species (such as Isoetes lacustris, Littorella uniflora and Lobelia dortmanna). Pollen data and old maps show that the dominating vegetation in the catchment area of Lake Grane...... clearly reduced the amounts of macrofossils for Isoetes sp., Lobelia sp. and Characeans. This suggests a reduction in their maximum distribution depth because of enhanced influx of terrestrial material and subsequently reduced water transparencies. Overall this paleo-study underlines the sensitivity...... of nutrient-poor soft water lakes to changes in their catchments vegetation and their partial irreversible consequences and is therefore of importance for lake management....

  2. Daniel Gallego Hernández (Ed.). Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

    Miguel Tolosa Igualada

    2016-01-01

    Daniel Gallego-Hernández (ed.). Current Approaches to Business and Institutional Translation. Proceedings of the International Conference on Economic, Business, Financial and Institutional Translation / Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suíça: Peter Lang, 2015, 254 páginas. ISBN 978-3-0343-1656-9.

  3. Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

    Miguel Tolosa Igualada

    2016-05-01

    Full Text Available http://dx.doi.org/10.5007/2175-7968.2016v36n2p291 Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

  4. mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome

    Beatriz Puisac

    2017-02-01

    Full Text Available Cornelia de Lange syndrome (CdLS is a congenital developmental disorder characterized by craniofacial dysmorphia, growth retardation, limb malformations, and intellectual disability. Approximately 60% of patients with CdLS carry a recognizable pathological variant in the NIPBL gene, of which two isoforms, A and B, have been identified, and which only differ in the C-terminal segment. In this work, we describe the distribution pattern of the isoforms A and B mRNAs in tissues of adult and fetal origin, by qPCR (quantitative polymerase chain reaction. Our results show a higher gene expression of the isoform A, even though both seem to have the same tissue distribution. Interestingly, the expression in fetal tissues is higher than that of adults, especially in brain and skeletal muscle. Curiously, the study of fibroblasts of two siblings with a mild CdLS phenotype and a pathological variant specific of the isoform A of NIPBL (c.8387A > G; P.Tyr2796Cys, showed a similar reduction in both isoforms, and a normal sensitivity to DNA damage. Overall, these results suggest that the position of the pathological variant at the 3´ end of the NIPBL gene affecting only isoform A, is likely to be the cause of the atypical mild phenotype of the two brothers.

  5. L’utilisation du prémélange de monensin chez les vaches laitières : un suivi simple et essentiel pour s’assurer d’une utilisation adéquate

    Dubuc, Jocelyn; Baril, Jean; DesCôteaux, Luc

    2009-01-01

    Le prémélange de monensin est utilisé fréquemment sur les fermes laitières canadiennes. L’ingrédient actif de ce produit est le monensin sodique. Bien que son utilisation chez les vaches laitières soit sécuritaire, des cas de surdose ont été rapportés à la suite de consommation de niveaux de monensin plus élevés que ceux recommandés. Un suivi hebdomadaire du pourcentage de matières grasses du réservoir de lait de la ferme devrait être fait de routine suite à la livraison d’aliment médicamenteux contenant du monensin pour détecter rapidement les situations de surdose. L’observation d’une baisse soudaine de la consommation volontaire de matière sèche et l’apparition de diarrhée dans un troupeau sont d’autres signes cliniques de surdose de monensin. Une détection rapide de ces cas permettra de corriger la situation. PMID:19721781

  6. Processes Governing Alkaline Groundwater Chemistry within a Fractured Rock (Ophiolitic Mélange Aquifer Underlying a Seasonally Inhabited Headwater Area in the Aladağlar Range (Adana, Turkey

    Cüneyt Güler

    2017-01-01

    Full Text Available The aim of this study was to investigate natural and anthropogenic processes governing the chemical composition of alkaline groundwater within a fractured rock (ophiolitic mélange aquifer underlying a seasonally inhabited headwater area in the Aladağlar Range (Adana, Turkey. In this aquifer, spatiotemporal patterns of groundwater flow and chemistry were investigated during dry (October 2011 and wet (May 2012 seasons utilizing 25 shallow hand-dug wells. In addition, representative samples of snow, rock, and soil were collected and analyzed to constrain the PHREEQC inverse geochemical models used for simulating water-rock interaction (WRI processes. Hydrochemistry of the aquifer shows a strong interseasonal variability where Mg–HCO3 and Mg–Ca–HCO3 water types are prevalent, reflecting the influence of ophiolitic and carbonate rocks on local groundwater chemistry. R-mode factor analysis of hydrochemical data hints at geochemical processes taking place in the groundwater system, that is, WRI involving Ca- and Si-bearing phases; WRI involving amorphous oxyhydroxides and clay minerals; WRI involving Mg-bearing phases; and atmospheric/anthropogenic inputs. Results from the PHREEQC modeling suggested that hydrogeochemical evolution is governed by weathering of primary minerals (calcite, chrysotile, forsterite, and chromite, precipitation of secondary minerals (dolomite, quartz, clinochlore, and Fe/Cr oxides, atmospheric/anthropogenic inputs (halite, and seasonal dilution from recharge.

  7. Description d'un nouveau brûleur compact. Fonctionnement en régime de gaz prémélangés Description of a New Compact Premixed Gas Burner

    Minetti R.

    2006-11-01

    Full Text Available On décrit un nouveau brûleur compact à gaz, de haut rendement et d'une puissance variable de 1 à 5 kW. La source de chaleur est une flamme plate d'un prémélange stoechiométrique de gaz naturel et d'air stabilisé sur une grille d'une surface de 100 cm2. Plusieurs grilles en acier inoxydable sont comparées. Elles diffèrent par leur épaisseur, le nombre et la dimension des trous. Un échangeur de chaleur en laiton à circulation d'eau peut être approché jusqu'à 7 mm de la surface du brûleur. La température des gaz frais, le débit et la position de l'échangeur ont été modifiés et les conditions optimales de fonctionnement sont décrites. Les températures à travers les gaz frais, la flamme, les gaz brûlés et les fumées, ont été mesurées. Un modèle simple des échanges de chaleurs est présenté. Il permet une meilleure compréhension des processus de transfert et facilite le choix des conditions opératoires. Dans les meilleures conditions, 93 % du contenu thermique du mélange gazeux est transféré à l'échangeur. Some general characteristics of a compact and efficient gas burner are described (1-5 kW. The heat source is a premixed flat flame stabilized on a 100 cm2 grid fed by a stoechiometric mixture of air and natural gas. Various types of stainless steel grids have been investigated. They differ according to their thickness and to the number and size of the holes. A circulating water heat exchanger made of brass can be approached to the flame as close as 7 mm above the burner surface. The temperature of the inlet gas mixture, the flow rate, and the position of the heat exchanger have been varied. The best working conditions are given as well as the temperature through the fresh gaseous mixture, the temperature profiles of the flame and the temperature of the fumes. From heat transfer calculations a simple model is presented. It gives better insight into the heat transfer processes and facilitates a judicious

  8. A novel KCNQ1 nonsense variant in the isoform-specific first exon causes both jervell and Lange-Nielsen syndrome 1 and long QT syndrome 1: a case report.

    Nishimura, Motoi; Ueda, Marehiko; Ebata, Ryota; Utsuno, Emi; Ishii, Takuma; Matsushita, Kazuyuki; Ohara, Osamu; Shimojo, Naoki; Kobayashi, Yoshio; Nomura, Fumio

    2017-06-08

    According to previous KCNQ1 (potassium channel, voltage gated, KQT-like subfamily, member 1) gene screening studies, missense variants, but not nonsense or frame-shift variants, cause the majority of long QT syndrome (LQTS; Romano-Ward syndrome [RWS]) 1 cases. Several missense variants are reported to cause RWS by a dominant-negative mechanism, and some KCNQ1 variants can cause both Jervell and Lange-Nielsen Syndrome (JLNS; in an autosomal recessive manner) and LQTS1 (in an autosomal dominant manner), while other KCNQ1 variants cause only JLNS. The human KCNQ1 gene is known to have two transcript isoforms (kidney isoform and pancreas isoform), and both isoforms can form a functional cardiac potassium channel. Here, we report a novel nonsense KCNQ1 variant causing not only JLNS, but also significant QTc prolongation identical to RWS in an autosomal dominant manner. Our case study supports that haploinsufficiency in the KCNQ1 gene is causative of significant QTc prolongation identical to RWS. Interestingly, the nonsense variant (NM_000218.2:c.115G > T [p.Glu39X]) locates in exon 1a of KCNQ1, which is a kidney-isoform specific exon. The variant is located closer to the N-terminus than previously identified nonsense or frame-shift variants. To the best of our knowledge, this is the first report showing that a nonsense variant in exon 1a of KCNQ1, which is the kidney-isoform specific exon, causes JLNS. Our findings may be informative to the genetic pathogenesis of RWS and JLNS caused by KCNQ1 variants.

  9. Production of Methanol-Higher Alcohol Mixtures from Natural Gas via Syngas Chemistry Production de mélanges méthanol-alcools supérieurs à partir du gaz, via (CO + H2

    Courty P.

    2006-11-01

    éactions, la déshydratation chimique des alcools par shift-conversionet la formation de produits lourds par croissance de chaîne. Ce dernier point conduit à limiter à 35-45 % en masse, la proportion d'alcools C2+ dans le mélange ciblé (fig. 1. Parmi les différents développements précités, IFP et Idemitsu Kosan ont sélectionné des catalyseurs oxydes mixtes à base de cuivre-cobalt ou cuivre-nickel, lesquels conduisent à des performances intéressantes et, notamment, à des alcools en mélange particulièrement purs. Enfin, l'analyse d'ensemble des données IFP et de la littérature ouverte démontre la fatalité de la coproduction parallèle d'hydrocarbures légers. Les principaux résultats sont les suivants : les catalyseurs cuivre-cobalt, fondés sur des systèmes oxydes mixtes alcalinisés, complexes, subissent de profondes transformations par réduction, puis interaction avec le milieu réactionnel. Leur sélectivité en alcools (fig. 3 varie en raison inverse de la proportion d'alcools C2+ produits. Le procédé de synthèse d'alcools (fig. 4 est fondé sur une technologie adiabatique, pour la section réactionnelle. Le fractionnement est mené par distillation azéotropique. L'intégration dans une chaîne gaz est présentée fig. 5; un rendement énergétique de 56-60% peut ainsi être obtenu. Deux démonstrations du procédé (fig. 6 ont été menées à bien et les mélanges d'alcools obtenus (tableau 5 ont fait l'objet d'essais sur flotte. Des performances typiques sont mentionnées tableau 6. Dans la chaîne gaz-alcools, la production de syngas représente 50% de l'investissement, mais la sélectivite en alcools constitue, en fait, le paramètre déterminant dans l'économie du procédé (tableau 8. L'étude du marché et des données économiques montre, enfin, que l'usage carburant constitue l'essentiel des possibilités de commercialisation. En zone industrialisée (fig. 7 ou en zone éloignée, peu industrialisée (fig. 8, soit le coût op

  10. Analysis of Simultaneous Gas-Liquid Flow Through an Orifice and Its Application to Flow Metering Etude de l'écoulement simultané d'un mélange gaz-liquide à travers un orifice et son application à la mesure du débit

    Pascal H.

    2006-11-01

    Full Text Available The purpose of this article is to show a more accurate orifice equation for a two-phase flow, such a compressible mixture of gas and liquid. The orifice equation given here con be used for the measurement of a gas-liquid mixture of fine emulsions by the orificemeter method. From the thermodynamic point of view, an equation of state has been formulated which provides the relationship between the specific mass of the mixture and pressure, under conditions of adiabatic expansion. The results obtained enable the mass flow rates of gas and liquid ta be determined without separation of the phases, provided thot the gas liquid mass ratio is known. The critical pressure ratio corresponding ta sonic velocity is also determined. Cet article présente une relation plus précise pour l'écoulement d'un système à deux phases, tel qu'un mélange compressible gaz-liquide, à travers un diaphragme. Cette relation peut être utilisée pour des mesures de mélanges gaz-liquide très finement divisés, c'est-à-dire des émulsions ou brouillards, par la méthode du diaphragme en paroi mince. Du point de vue thermodynamique, on a formulé une équation d'état donnant la relation entre la masse spécifique du mélange et la pression dans des conditions d'expansion adiabatique. Les résultats obtenus per-mettent de déterminer le débit massique du gaz et du liquide, sans séparation des deux phases, à condition que le rapport de masse gaz-liquide soit connu. On détermine également le rapport de pression critique correspondantà la vitesse du son.

  11. Mersin ilindeki orman yangınlarının başlangıç noktalarına göre mekânsal analizi (2001-2013

    Dr. Celalettin DURAN

    2014-12-01

    Full Text Available Orman yangınları, Akdeniz ikliminin egemen olduğu bölgelerde afet riski taşır. Sık ve büyük orman yangınları önemli sosyo-ekonomik ve ekolojik sonuçlara neden olur. Mersin ili sahip olduğu orman varlığı, artan nüfusu ve diğer coğrafi özellikleri (iklimi, topografyası, vd. ile orman yangınlarına karşı son derece hassastır. Bu nedenle, her yıl çok sayıda orman yangını meydana gelir. Bu çalışma ile Mersin Orman Bölge Müdürlüğü kayıtlarındaki (2001-2013 yılları arası 1038 orman yangınının başlangıç noktaları esas alınarak mekânsal dağılımları belirlenmiştir. Yangın sayısına göre, kategorik olarak sınıflandırılmış ve ağırlık değerleri hesaplanmış faktör haritaları elde edilmiş ve bu haritalar yardımıyla, potansiyel orman yangınları için yangına hassas yöreler sınıflanmıştır. Bu sınıflamaya göre, büyük yerleşim yerlerine yakın kızılçam ormanları, en hassas yöreler olarak ön plandadır. İlin orta bölümündeki maki yayılış alanı ile yüksek plato alanlarına geçiş kuşaklarındaki ormanlar ise hassasiyetin en az olduğu yörelerdir.

  12. Etude numérique et expérimentale de l'evaporation d'une ou plusieurs gouttes de mélange de carburants dans un écoulement chauffé

    Daïf, A.; Ali Chérif, A.; Bresson, J.; Sarh, B.

    1995-10-01

    The vaporization of one or two multi-component fuel droplets in hot air-stream is presented. A thermal wind tunnel with experimental channel has been designed to develop an experimental process. Firstly, the comparison between experimental results and numerical data is presented for the case of an isolated multi-component droplet. The numerical method is based on the resolution of heat and mass transfer equations between the droplet and the gas stream. This model includes the effect of Stephan flow, the effect of variable thermophysical properties of the components, and the non-unitary Lewis number in the gas film. The experimental results show the micro-explosion phenomenon observed in the liquid phase of multi-component droplet at low temperature. The experimental case of two pure or multi-component droplets in interaction is also presented. On présente un article de synthèse sur l'évaporation d'une ou deux gouttes de carburants à plusieurs composants dans un écoulement d'air chaud. Un dispositif expérimental constitué d'une soufflerie thermique, avec veine d'expérimentation, est réalisé pour permettre cette étude. Pour le cas d'une goutte isolée, une comparaison expérience-calcul est entreprise. Le principe de la méthode numerique consiste en la résolution des équations de transfert de masse et de chaleur entre la goutte et l'écoulement. Ce modèle prend en compte les effets de l'écoulement de Stephan, les variations des propriétés thermophysiques des composants dans les deux phases et la valeur du nombre de Lewis différente de l'unité dans le film de vapeur. Outre l'analyse plus approfondie qu'apporte la confrontation entre le calcul et l'expérience, les résultats expérimentaux montrent le phénomène de micro-explosion observé à l'intérieur de la goutte liquide. Le cas expérimental de deux gouttes en interaction est abordé qu'il s'agisse de gouttes de carburant pur ou de mélange.

  13. Modélisation informatique de la production d’énergie renouvelable à partir de biogaz par transformation anaérobique dumélange de résidus d’agrumes et defumier de bovins

    Edwin Dario Cendales L.

    2014-03-01

    Full Text Available Dans cet article nous avons simulé par ordinateur le processus de digestion anaérobique d’un mélange homogénéisé de fumier bétail et de résidus d’agrumes afin d’évaluer la viabilité des énergies renouvelables à partir de la transformation des déchets. Sur la base des résultats obtenus et grâce au développement de la phase expérimentale lors de laquelle étaient mesurées de façon périodiques les variables de contrôle du processus de biodégradation anaérobique tels que le pH, l’alcalinité, la demande chimique en oxygène (total et soluble, nous avons établi les performances des paramètres du processus et déterminé des valeurs pour la comparaison entre résultats expérimentaux et résultats informatiques. Nous avons en outre réalisé une simulation du processus de digestion anaérobique dans des conditions similaires à celles précédemment établis par d’autres essais expérimentaux à travers la mise en oeuvre du modèle ADM-1. Grâce aux résultats obtenus par le biais de simulations et mesures expérimentales, nous avons évalué la précision du modèle concernant les valeurs des mesures expérimentales. Un modèle simplifié pour l’évaluation de l’énergie produite par une installation à échelle réduite qui effectue le traitement anaérobique des résidus organiques a finalement été mis en place. Le modèle a montré qu’il existe au départ un déficit énergétique pour que le processus se réalise, mais une fois la production de biogaz enclenchée, le processus devient autonome et le système fournit une quantité croissante d’énergie disponible.

  14. Ternary Mixtures of N-Docosane, N-Tricosane and N-Tetracosane Mélanges ternaires de n-docosane, n-tricosane et n-tétracosane

    Nouar H.

    2006-11-01

    Full Text Available Binary phase diagrams of the systems: n-docosane: n-tricosane (C22H46 : C23H48, n-tricosane: n-tetracosane (C23H48: C24H50 and n-docosane: n-tetracosane (C22H46: C24H50 have been established by means of structural and differential scanning calorimetry analyses. On the basis of these results and of X-ray examination of forty one ternary mixtures, it is proposed the ternary phase diagram (C22H46: C23H48: C24H50 at room temperature. This work has indicated the existence of limited terminal solid solutions near the three pure n-alkanes and three domains of orthorhombic intermediate phases (noted ß' 1, ß'' 1, ß' 2 identical to those observed in the binary systems. X-ray experiments have showed that the phases ß' 1, ß'' 2 situated on the both sides of the middle intermediate phase ß' 1, are isostructural as in the binary systems. Les diagrammes de phases des systèmes binaires : n-docosane : n-tricosane (C22H46 : C23H48, n-tricosane : n-tétracosane (C23H48 : C24H50 et n-docosane : n-tétracosane (C22H46 : C24H50 ont été établis à partir d'analyses thermiques différentielles (ATD et structurales. Sur la base de ces résultats, ainsi que de l'examen aux rayons X de 41 mélanges ternaires, le diagramme de phases du ternaire (C22H46 : C23H48 : C24H50 à température ambiante est proposé. Ce travail a indiqué l'existence de domaines limités de solutions solides au voisinage des trois n-alcanes purs, ainsi que de trois régions de phases intermédiaires orthorhombiques (notées ß' 1, ß 1, ß' 2 identiques à celles observées avec les systèmes binaires. Les analyses aux rayons X ont montré que les phases ß' 1 et ß' 2 situées de part et d'autre de la phase médiane intermédiaire ß1 sont isostructurales, tout comme dans le cas des systèmes binaires.

  15. Serieuze vergroening blijft niet lang meer uit

    Noort, van F.R.

    2015-01-01

    Gaan we weer natuurlijke indigo gebruiken als kleurstof van spijkerbroeken? Zal de grootste fabrikant van cola straks weer échte vanille gebruiken in plaats van synthetische smaakmakers? Veel consumenten kiezen bewust voor producten op natuurlijke basis. De glastuinbouw kan goed op deze trend

  16. Het lange-QT-tijdsyndroom bij kinderen

    Ten Harkel, A.D.J.; Lubbers, L. J.; Hoorntje, Th.; Blom, N.A.; Van Langen, I.M.; Sreeram, N.; Wilde, A.A.M.

    2002-01-01

    We examined 29 pediatric patients with long-Qt-syndrome in three academic hospitals. The mean age was 10 years (3-17). Of these patients 22 used betablocker therapy, in three combined with pacemaker. Genotyping has been performed in 22 children. LQTSI (mutation in the KCNQ1 gene) was found in

  17. Narkoboss langes verises lahingus / Heiki Suurkask

    Suurkask, Heiki, 1972-

    2009-01-01

    Mehhiko mereväe eriüksuse rünnakus hukkusid narkojõugu juhid, vanimad kurikuulsatest Beltran Leyva vendadest Marcos Arturo ja Mario Alberto. Mehhiko president Felipe Calderon kuulutas 2006. a. narkokartellide vastu sõja

  18. Genetics Home Reference: Cornelia de Lange syndrome

    ... Saitoh K, Komata M, Katou Y, Clark D, Cole KE, De Baere E, Decroos C, Di Donato ... medicine? What is newborn screening? New Pages Lyme disease Fibromyalgia White-Sutton syndrome All New & Updated Pages ...

  19. Lange-termijneffecten van sales promotion

    Spijkerman, F.M.; Snelders, H.M.J.J.

    1990-01-01

    Sales promotion wordt binnen de marketing gehanteerd als instrument om op de korte termijn direct koopgedrag in de gewenste richting te beïnvloeden. Daarbij wordt vaak voorbijgegaan aan de mogelijke effecten op de langere termijn. F.M. Spijkerman en H.M.J.J. Snelders geven evenwel aan dat sales

  20. The Brachmann-De Lange Syndrome

    1974-05-04

    May 4, 1974 ... to hospital because of failure to thrive, bronchopneumonia and kwashiorkor. The parents, 3 older sisters and 2 older brothers were physically and mentally normal. There was no history of significant family illness or exposure to drugs during pregnancy and the young parents were not related. The patient ...

  1. Hazlitt, Hamlet ja kadunud kangelane / Anne Lange

    Lange, Anne

    1998-01-01

    Inglise esseist, romantikute põlvkonna tähtsamaid kriitikuid William Hazlitt (1778-1830). Refereeritud ka 24. juuli The Times Literary Suplementis ilmunud Paul Keegani retsensiooni Tom Paulini Hazlitti-raamatust 'Vabaduse koidutäht' (The day-star of liberty)

  2. Mellow Mélange: Marge and Blanche

    Elias, Camelia

    2010-01-01

    of expression by allowing tensions such as the ones between genders to operate in the gaps between contextual transitions from imperial selves to montage selves, from beauty to potency, from production to consumption, from the world of thinking to visual thinking. Against this background of the US in the 40s...... and 50s, The Simpsons, while paying tribute to good performances on stage that portray both inner and social realistic drama, also highlights the melodramatic aspect of any transition. The fact that Marge participates in a musical rather than in a theatrical performance à la Blanche who emphasizes...

  3. Le combat avec l'ange

    Christian Lalive d’Épinay

    2007-06-01

    Full Text Available L'auteur « revisite » le parcours qui l'a conduit à réaliser dans les années 1960 une des premières études du mouvement évangélique pentecôtiste en Amérique latine. Il rappelle d'abord les termes par lesquels il avait prétendu cadrer sa relation avec son objet de recherche, pour décrire ensuite l'étrange dialectique sujet/objet qui s'était développée au fur et à mesure de son immersion dans une double altérité, l'Amérique latine et le mouvement charismatique. Pendant ce voyage au long cours, l'« objet » avait pris vie ; il était devenu un sujet qui imposait au chercheur qui s'était cru « sujet » des interrogations nouvelles en même temps qu'une mise en question de ses certitudes du départ.The combat with the angel. Concerning a study on the Pentecostal movement in ChileThe author retraces the path that led him in the 1960s to carry out one of the first studies on the Pentecostal evangelical movement in Latin America. After recalling the terms on which he sought to situate his relationship with the research topic, he goes on to describe the strange subject/object dialectic that developed as he gradually became more and more immersed in a dual otherness, Latin America and the charismatic movement. During this lengthy voyage, the “object” of his research took on a life of its own, mutating into a subject that confronted the researcher (who had assumed that he was the “subject” with new questions and a need to reconsider his initial certitudes.La pelea con el ángel. Acerca de un estudio del movimiento pentecostal en ChileEl autor “revisita” el camino que lo había llevado a desarrollar uno de los primeros estudios sobre el movimiento evangélico pentecostal en América latina en los años’60. Recuerda primero los términos con los que había pretendido encuadrar la relación con su objeto de investigación, para describir luego el extraño vínculo sujeto/objeto que se había ido generando mientras progresaba en su inmersión dentro de una doble alteridad: América latina y el movimiento carismático. Durante este viaje a tierras lejanas, el “objeto” empezó a tener vida, y poco a poco se le impuso como “sujeto” al investigador, que se consideraba a sí mismo como “sujeto”, imponiéndole nuevos interrogantes y una revisión radical de sus certidumbres iniciales.

  4. GMO is dood, lang leve de gentechniek

    Arendonk, van J.A.M.

    2004-01-01

    Nu de consument met geen stok aan de gmo-voeding is te krijgen, bloeit de aandacht voor klassieke veredeling op. Dit traditionele proces plukt echter ook de vruchten van gentech. Er kan gerichter veredeld worden, met als resultaat tropisch fruit dat niet bederft tijdens de verscheping, of wellicht

  5. Riedel, Wolfgang; Lange, Horst (Hrsg.): Landschaftsplanung

    Schlosser, Siegfried

    2013-01-01

    Endlich liegt für einen breiten Nutzerkreis ein aktuelles, alle wesentlichen Bereiche der Landschaftsplanung behandelndes Lehrbuch vor! Erfreulich auch, dass durch die langjährige berufliche Tätigkeit mehrerer beteiligter Autoren im Osten Deutschlands, insbesondere der beiden Herausgeber, viele Erfahrungen aus der Landschaftsplanung der neuen Bundesländer mit einbezogen werden konnten.

  6. Allilma ja pealilma dilemma / Rein Lang

    Lang, Rein, 1957-

    2007-01-01

    Justiitsminister kirjutab organiseeritud kuritegevusest Eestis, toob näiteid riikidest, kus on püütud organiseeritud kuritegevuse abil lahendada oma probleeme ning peab oluliseks, et riigi koostöö sellega peab olema võimatu. Kaitsepolitsei ja keskkriminaalpolitsei tähtsus organiseeritud kuritegevuse kaotamisel

  7. Vajame uut suhtumist sisejulgeolekusse / Rein Lang

    Lang, Rein, 1957-

    2006-01-01

    Ilmunud ka: Hiiu Leht 31. märts lk. 2, Elva Postipoiss 1. apr. lk. 4, Harjumaa, Vooremaa 4. apr. lk. 2, Sakala, Põhjarannik, Severnoje Poberezhje, Võrumaa Teataja 6. apr. lk. 2, Koit 8. apr. lk. 6, Valgamaalane 18. apr. lk. 2, Pärnu Postimees 21. apr. lk. 11. Justiitsminister Rein Langi hinnangul ei seisne sisejulgeoleku arendamine üksnes politseinike ja päästjate palkade tõstmises, sisejulgeolek jaguneb vähemalt nelja ministeeriumi haldusalasse

  8. Uventet lang virkningsvarighed afmuskelrelaksantia kan forebygges

    Madsen, Matias Vested; Øberg, Emilie; Rosenberg, Jacob

    2015-01-01

    Muscle relaxation facilitates tracheal intubation and improves surgical conditions during anaesthesia. However, unexpected prolonged muscle relaxation may occur. This article describes important causes of prolonged muscle relaxation and gives suggestions for its prevention. Drug interactions, inc......, incomplete reversal, co-morbidity, inaccurate neuromuscular monitoring and critical illness may prolong the effect of muscle relaxants. The anaesthetist must titrate the muscle relaxants using objective neuromuscular monitoring and proper reversal of the blockade when needed....

  9. De Man van Smarten, een leven lang

    van den Belt, Hendrik; Kunz, A. J.; Vergunst, P. J.

    2017-01-01

    This meditative explanation of the formula in the Apostles Creed "who suffered under Pontius Pilate" reflects on its meaning in Early Christianity and in the Reformation. Originally a reference to the historical reality of the suffering and crucifixion of Christ, in the Reformation Pontius Pilate

  10. Effect van ozontoepassing in lange bewaring Conference

    Geijn, van de F.G.

    2012-01-01

    Ozon toepassing heeft op basis van deze proef en voorliggende ervaringen geen grote effecten in de reductie van rot en schimmels bij langdurige Conference bewaring. Gezien het beperkte effect op rot onderdrukking op één van de herkomsten met een hoger aantastingspercentage rot kan ook niet gesteld

  11. 2806-IJBCS-Article-Firmin Semboung Lang

    hp

    simulation of hydrocarbon degradation by bacteria requires the addition of nitrogen and phosphorus. Biodegradation is ... involves the nitrogen and phosphorus involved in protein synthesis. When the ...... Molecular-Weight Polycyclic Aromatic.

  12. Un nouveau moyen de mesure absolue du taux gazeux des mélanges gaz-liquides : le SMAC A New Absolute Measurement of the Volumetric Gas Ratio of Gas-Liquid Mixture: the Smac

    Porot P.

    2006-11-01

    Full Text Available Du graphe (P, V de la compression d'un mélange gaz-liquide, on peut tirer la valeur du taux volumique de gaz dans le mélange. La vérification théorique et expérimentale de ce principe ainsi que ses limites d'application comme moyen de mesure sont présentées. Ce résultat a été utilisé pour développer un système de mesure de l'aération de l'huile moteur, le SMAC (Système de Mesure d'Aération par Compressibilité. Des exemples d'application, tels que l'étude de la sensibilité de certaines huiles à l'aération, sont exposés. Oil aeration can be a real problem in engine oil circuit. The involved lubrication power decrease and thermic properties changes can damage the engine. Furthermore, the increased compressibility is very dangerous for hydraulic systems like valve lash adjusters. A first step to control this aeration is to be able to measure it. Gammametry is often used but this measurement needs a very precise calibration and is quite complicated and dangerous. A new absolute measurement has been discovered, based on the difference of compressibility between air and oil. It is absolute because the measurement principle is independant of the conditions, The system does not need a new calibration at each new environment. It is valid for any gas-liquid mixture. From the (P, V graph of a gas-liquid mixture compression, one can derive the gas-liquid volumetric ratio. The log-log graph (P/PO, 1-V/VO of a mixture sample pressurization always shows an inflexion point. The y value of this inflexion point (1-V/VO is equal to the volumetric gas ratio of the sample (before compression. This phenomenon is obvious on hydraulic curves (see Annexe 1. To check it, we have proceeded to a theoretical demonstration and an experimental verification. The theoretical demonstration of this principle concludes that the principle is verified as long as the ration P index 0 / alpha B is small. B is the oil bulk modulus, alpha is the volumetric gas ratio

  13. 从对电视剧《施琅大将军》的争论看 中国文化民族主义复兴的困境 (The Dilemma of Chinese Cultural Nationalism: the Case of the TV Program 'General Shi Lang'

    Mobo Gao

    2007-01-01

    Full Text Available With the rise of China's status on international stage as a result of its economic development there is an increasingly audible voice of Chinese cultural nationalism. More and more educators and intellectuals are calling for the revival of Chinese traditional culture values. However, the very issues of who are the Chinese and what are traditional Chinese cultural values present a huge dilemma. The debates on a recent a TV program "General Shi Lang" consist a good case to illustrate this dilemma. Shi Lang was a general of the last days of the Ming Dynasty, but had surrendered to the Manchu Qing dynasty invaders and fought for the Machus take over Taiwan from a Chinese ruler. The debates show that the dilemma has its cause in at least three issues. First, it is not at all obvious who should be categorized as Chinese. Secondly, it is not at all obvious what Chinese cultural values are. And finally it is the issue of evaluation of traditional values against the universal claim of the values of liberal democracy.

  14. Ferropericlase inclusions in ultradeep diamonds from Sao Luiz (Brazil): high Li abundances and diverse Li-isotope and trace element compositions suggest an origin from a subduction mélange

    Seitz, Hans-Michael; Brey, Gerhard P.; Harris, Jeffrey W.; Durali-Müller, Soodabeh; Ludwig, Thomas; Höfer, Heidi E.

    2018-05-01

    -abundances, and an extremely large and incoherent range in Mg# and Cr, Ni, Mn, Na contents in the ferropericlase inclusions suggests that their protoliths were members of the above lithologies. This mélange of altered rocks originally contained a variety of carbonates (calcite, magnesite, dolomite, siderite) and brucite as the secondary products in veins and as patches and Ca-rich members like rodingites and ophicarbonates. Dehydration and redox reactions during or after deep subduction into the transition zone and the upper parts of the lower mantle led to the formation of diamond and ferropericlase inclusions with variable compositions and a predominance of the Ca-rich, high-pressure silicate inclusions. We suggest that the latter originated from peridotites, mafic rocks and sedimentary rocks as redox products between calcite and SiO2.

  15. Potentiel des moteurs à mélange pauvre face aux moteurs actuels à réglage stoechiométrique : consommation, émissions, exigence en octane The Challenge to Modern Stoichiometric Engines by the Potential Lean-Burn Engine: Consumption, Emissions, Fuel Requirements

    Douaud A. M.

    2006-11-01

    Full Text Available Le moteur à allumage commandé pour application automobile aux États-Unis est généralement dépollué par catalyse trifonctionnelle qui impose un contrôle stoechiométrique du mélange air-carburant. Le contexte européen de 1990 pour la qualité de l'air stimule l'industrie automobile dans ses recherches de solutions techniques performantes. Le moteur à mélange pauvre, performant en consommation, est une solution potentielle si l'émission de NOx peut être maîtrisée par la combustion. Cet objectif nécessite une conception du moteur contrôlant la turbulence et l'hétérogénéité du mélange air + carburant + résiduels pendant la combustion. La longévité de l'adaptation optimale moteur-carburant nécessitera un contrôle électronique de l'allumage et l'utilisation d'additifs détergents. Pour satisfaire les réglementations les plus sévères, les émissions de CO et HC pourront être contrôlées par un simple pot catalytique d'oxydation. Des oxydes de métaux non précieux introduits dans la formule catalytique en addition aux métaux précieux maintiennent la fonction oxydante pendant les transitoires en mélange riche tout en réduisant partiellement les NOx. Une vue d'ensemble de ce concept basé sur des simulations numériques et des résultats expérimentaux de consommation, d'émission, d'exigence en octane, etc. est présentée. Spark-ignition engines for automotive applications in the United States are currently depolluted by a 3-way catalyst that requires air-fuel control at stoichiometry. The 1990 European context for air pollution control is stimulating the automotive industry to search for improved technical solutions. The lean-burn engine is a potential fuel-efficient answer if its combustion can be optimized for low NOx emissions. Achieving this challenging approach requires engine design to control the turbulence and heterogeneity of the air + fuel + residual mixture during combustion. Electronic ignition

  16. A Contribution to Turbulent Combustion: Premixed Flames and Material Surfaces Une contribution à la combustion turbulente : flammes prémélangées et surfaces des matériaux

    Nicolleau F.

    2006-11-01

    from each other. The turbulent diffusion process is very active to create new burning zones. This diffusion process is closely related to both the intensity and the length scale of the turbulent field. That explains the dominant role of turbulence and the adaptation of the burning rate to the rotation speed in combustion engines. Additional information useful for the reader is reported in Appendices I and II. Le comportement des flammes de prémélange a été examiné par de nombreux auteurs. En fait, le problème de la combustion en milieu turbulent repose pour beaucoup sur des comparaisons d'échelles. Dans le présent article, une première étude porte sur l'évolution d'une surface matérielle (qui peut être assimilée sous certaines conditions à une surface de flamme. On utilise successivement une démarche analytique et une démarche numérique. On constate alors la rapidité d'extension de la surface et le rôle prépondérant des petites échelles ce que confirme l'étude analytique. Les risques d'extinction sont prédits en général par comparaison d'échelles. D'une simulation directe conduite sur un cas spécifique, Poinsot confirme l'idée que ce ne sont pas les structures ayant les échelles caractéristiques de la flamme qui sont les plus redoutables, mais des structures de taille quelque peu plus grande. Dans un précédent article, le rôle cumulé des gradients locaux avait été signalé. Nous donnons à ce concept une forme quantitative en utilisant le ß modèle lequel définit un taux d'occupation de l'espace en fonction du rang (et donc de la dimension de structures. Un calcul de gradient cumulé redonne la prédiction de Poinsot. Enfin, le même ß modèle est utilisé pour définir une nouvelle zone dans la région de combustion distribuée. Des balles fluides brûlent isolément tandis qu'un processus de diffusion lié très étroitement au champ turbulent et à son intensité crée d'autres points d'allumage. Le mécanisme explique l

  17. Meduus Riia rannas / Galina Timtšenko ; intervjueerinud Mihhail Trunin ; tõlkinud Mait Eelrand

    Timtšenko, Galina

    2016-01-01

    Intervjuu veebiväljaande Lenta.ru endise peatoimetaja, portaali Meduza looja ja peadirektori Galina Timtšenkoga veebilehest Meduza, ajakirjanduse arengusuundadest ning Baltimaades tegutsevate venekeelsete massiteabevahendite iseärasustest

  18. Oluline teatmeteos, mis võinuks olla veelgi parem / Mait Talts

    Talts, Mait, 1964-

    2010-01-01

    Arvustus: Eesti perioodika 1941-1944 = Estnische Periodika 1941-1944 = Periodicals in Estonia 1941-1944 = Эстонская периодика 1941-1944 / Eesti Rahvusraamatukogu ; koostanud Külli Kaunissaar. Tallinn, 2009. (Eesti retrospektiivne rahvusbibliograafia)

  19. Ettevõtte konkurentsieelis inimeste analüüsi abil / Mait Raava

    Raava, Mait

    2015-01-01

    Ettevõtte töötajate analüüsimisest, analüütika tulemuste rakendamisest juhtivates ettevõttes. Viiest sambast, millel põhineb inimeste analüüsi edukas rakendamine, analüütika rakendamise etapid

  20. Majad ja muutumised marsruudil JPN-USA-EST / Tomomi Hayashi ; intervjueerinud Mait Väljas

    Hayashi, Tomomi, 1971-

    2011-01-01

    Intervjuu Jaapanis Toyamas sündinud ning Eestis elava ja töötava arhitekti Tomomi Hayashiga, kes aastast 2004 on HG Arhitektuur OÜ arhitekt ja partner. Endast, tööst New Yorgis Rafael Viñoly büroos, Eestisse tulekust, oma tööpõhimõtetest, lemmikarhitektidest, järgmisest ehitusbuumist jm. Loetletud T. Hayashi töid, preemiad

  1. Mait Müntel lahendab teaduse suurt ristsõna / intervjueerinud Kristi Helme

    Müntel, Mait

    2010-01-01

    Intervjuu keemilise ja bioloogilise füüsika instituudi noore teadlasega, kes pälvis Vabariigi Presidendi Kultuurirahastu noore teadlase preemia. Ta on kaitsnud doktoritöö teemal „Topeltlaetud Higgsi bosoni detekteerimine CMS-i detektoril”

  2. Overview of the M.A.I.T. analysis system (machine analysis of the internal threat)

    NiCastro, J.R.

    1978-01-01

    The problem of the internal threat epitomized by the tactics of collusion and illicit use of access has been structured into a data processing format. The format procedures and analysis are objective; the flexibility of the method allows the security analyst to input his judgment and opinions into the code. By so doing he can interact and determine the effects of interacting with the safeguard system

  3. Applying theory of constraints in tactical and strategic management / Kalev Kaarna, Mait Miljan

    Kaarna, Kalev

    2002-01-01

    Bibliogr. lk. 86-87. - Kokkuvõte eesti keeles lk. 87. Piirangute teooria kasutamise vajadusest ja võimalustest. Piirangute juhtimisest pikas perspektiivis ning sellel põhinevast strateegilisest juhtimisest. Tabelid

  4. Soomlaste graafiline betoon nüüd ka Eestis / Mait Eelrand

    Eelrand, Mait

    2007-01-01

    Graafilise betooni meetodi arendas 1990. aastate lõpul välja soome sisearhitekt Samuli Naamanka, tehnoloogia on patenteerinud tema asutatud firma Graphic Concrete Oy. AS E-Betoonelement kasutas graafilise betooni tehnoloogiat esimesena Rakveres büroohoone fassaadi kujundamiseks. Kommenteerivad Graphic Concrete Oy tegevdirektor H. Lanningu ja K. Meus AS-st E-Betoonelement

  5. Tagasisidet peab töötajale vahendama ülemus / Mait Raava

    Raava, Mait

    2004-01-01

    Autor teeb lühiülevaate 360ʻ ja teiste tagasiside meetodite rakendamisest maailmas alates 1950ndatest aastatest ning juhib tähelepanu vigadele, mida meetodi rakendamisel on tehtud. Kommenteerib Irene Metsis. Skeem: Juht saab tagasiside nelja kanali kaudu. Vt. samas: Rollist tulenevalt on tagasiside erinev

  6. Turuanalüüs - eduka turunduse juhtimise üks võtmetegur / Mait Miljan

    Miljan, Mait

    2002-01-01

    Ettevõtte turunägemuse kujundamisel puutub kokku selliste mõistetega nagu turu definitsioon, turu arenguindeks (Market - MDI), turupotentsiaal, turunõudlus, turuosa arenguindeks (Share Development Index - SDI). Diagrammid

  7. Kulu- ja turupõhisest hinnakujundamise strateegiast turunduses / Mait Miljan, Kalev Kaarna

    Miljan, Mait

    2005-01-01

    Tänapäevases ärikeskkonnas soovitavad autorid kasutada kombineeritud mudelit, milles rakendatakse kulu- ja turupõhist strateegiat lähtuvalt ettevõtte turusituatsioonist, tegevusvaldkonnast ning püütakse liikuda ühtse hinnakujundamiseni tarneahelas kui tervikus. Skeemid

  8. NOMAD on the ExoMars TGO 2016 mission: MAIT and characterisation testing

    Vandaele, Ann C.; Neefs, Eddy; Lopez-Moreno, J. J.; Rodriguez Gomez, Julio; Drummond, Rachel; Patel, Manish; Thomas, Ian; Gissot, Samuel; Depiesse, Cedric; Ben Moussa, Ali; Giordanengo, Boris; Bellucci, Giancarlo

    NOMAD, the “Nadir and Occultation for MArs Discovery” spectrometer suite has been selected by ESA and NASA to be part of the payload of the ExoMars Trace Gas Orbiter mission 2016. This instrument suite will conduct a spectroscopic survey of Mars’ atmosphere in the UV, visible and IR regions covering the 0.2-0.65 and 2.2-4.3 μm spectral ranges. NOMAD’s observation modes include solar occultation, nadir and limb observations. The NOMAD instrument is composed of 3 channels: a solar occultation only channel (SO) operating in the infrared wavelength domain, a second infrared channel capable of observing nadir, solar occultation and limb observations (LNO), and an ultraviolet/visible channel (UVIS) that can work in all observation modes. The spectral resolution of SO and LNO surpasses previous surveys in the infrared by more than one order of magnitude. NOMAD offers an integrated instrument combination of a flight-proven concept (SO is a copy of SOIR on Venus Express), and innovations based on existing and proven instrumentation (LNO is based on SOIR/VEX and UVIS has heritage from the ExoMars lander), that will provide mapping and vertical profile information at high spatio-temporal resolution. The three channels have each their own ILS and optical bench, but share the same single interface to the S/C. The NOMAD flight model is due for delivery to ESA in January 2015. We will present results so far of the manufacturing, assembly and especially testing of the various components. The UV CCDs have been characterised in thermal-vacuum; optical fibres have been studied with UV exposure to look at transmission degradation; the IR AOTFs have been tested for their transfer functions; lifetime and vibration testing has been carried out on the flip mirror mechanism. These are all vital inputs to the scientific results from NOMAD. Acknowledgements - The research program was supported by the Belgian Federal Science Policy Office and the European Space Agency (ESA PRODEX program). IAA participation is funded by MICIIN through Plan Nacional Ref. AYA2009-08190. UVIS support provided by the Open University and partly by STFC. Italian participants acknowledge the support from ASI.

  9. Thermodynamic and Kinetic Aspects of the Dissolution of Quartz-Kaolinite Mixtures by Alkalis Aspects thermodynamiques et cinétiques de la dissolution des mélanges quartz-kaolinite par les alcalis

    Labrid J.

    2006-11-01

    'ensemble des données expérimentales indique que, outre l'adsorption de l'acide silicique Si(OH4 et de l'ion (***, il est nécessaire de faire appel à un autre mécanisme d'inhibition que l'on suppose joué par l'analcime adsorbée. Il est raisonnable de penser qu'avant précipitation, l'analcime est fixée sur la surface quartzeuse qui agit comme support à la nucléation. Ces hypothèses conduisent à un nouveau schéma cinétique qui inclut ces différents mécanismes d'adsorption. Les concentrations calculées en silicium et en aluminium solubilisés s'accordent bien aux données expérimentales pour des temps de réaction allant jusqu'à 3 000 heures. Les études faites sur la kaolinite ont montré que ce minéral est aussi capable d'adsorber l'aluminium, vraisemblablement sous la forme d'ion (***. Une procédure de traitement de l'argile est proposée en préalable à toute étude cinétique afin d'éliminer les espèces adsorbées. Dans ces conditions, la dissolution de la kaolinite est congruente. Par analogie avec la dissolution du quartz, et compte tenu de la structure minéralogique de la kaolinite, nous avons proposé un schéma cinétique de dissolution de l'argile qui décrit la co-adsorption des espèces Si(OH4 et (***, préalablement à la formation du cristal. La validité de ces mécanismes cinétiques a été examinée en menant des expériences de dissolution de mélanges de quartz et de kaolinite. La modélisation de l'attaque a été faite en prenant en compte les processus d'adsorption et de précipitation observés. Le modèle adopté qui traduit le couplage des processus élémentaires de dissolution permet le calcul des concentrations en aluminium et silicium solubilisés. La comparaison avec l'expérience indique qu'il est nécessaire d'attribuer à l'argile une réactivité notablement supérieure à celle déterminée avec le minéral isolé. Il est suggéré que le sable pourrait jouer un rôle sur l'état de dispersion de l'argile avec corr

  10. Influence of trihalomethanes according to Koppën climatological classification and Lang's index, on mortality associated with stomach and bladder cancer by geographic areas in Spain Influencia de los trihalometanos según la clasificación climatológica de Koppën y el índice de Lang, sobre la mortalidad asociada al cáncer de estómago y vejiga por áreas geográficas en España

    Agustín Llopis González

    2011-12-01

    Full Text Available The present study aims to determine the levels of trihalomethanes (THMs in drinking water from different Spanish cities, and assess whether the temperature and rainfall influence them. Also assess the possible association of THM to mortality from stomach cancer and bladder. For this we took water samples from 49 cities in 2002, 2005 and 2006, which were analyzed by gas chromatography coupled with mass spectrometry obtaining THM levels. Climatic classifications were made according Koppën Lang and index the data of temperature and precipitation, and finally death rates from cancer of the stomach and bladder were standardized by sex and age. We found a decrease in the levels of THMs in Spain over time, managing to be below the limits established by Royal Decree 140/2003, but three cities studied. The results indicate that climatic classifications most of the Spanish territory has a temperate climate type - Wet. However it was found that different climatic zones exhibit an influence on the levels of THMs. Nor was significant correlation of the levels of THM with cancer of stomach and bladder, but is significant between stomach cancer and Köppen climate classification. It should continue with studies that include other variables allow clarifying and / or strengthening these results.El presente trabajo tiene como objetivo conocer los niveles de trihalometanos (THM en el agua potable de diferentes ciudades españolas y evaluar si la temperatura y las precipitaciones influyen sobre ellos. También, valorar la posible asociación de los THM con la mortalidad por cáncer de estómago y vejiga. Para esto, se tomaron muestras de agua de 49 ciudades en el 2002, 2005 y 2006, las cuales se analizaron por cromatografía de gases acoplada a espectrometría de masas, obteniendo los niveles de THM. Se realizaron las clasificaciones climáticas según Koppën y el índice de Lang con los datos de temperatura y precipitación y, por último, las tasas de

  11. Développement d'un moteur 4-soupapes fonctionnant en mélange dilué. Une nouvelle approche basée sur l'optimisation de l'aérodynamique interne Application of Flow Field Optimization to Lean Burn Engine Development. A New Approach Based on Internal Flow Field Optimization

    Henriot S.

    2006-11-01

    Full Text Available L'objectif du projet GSM Moteur de Synthèse à Allumage Commandéest de concevoir un moteur fonctionnant en mélange pauvre à la fois dépollué et économe. La première phase analyse finement sur moteur monocylindre les interactions entre l'aérodynamique et la combustion qui déterminent l'aptitude au fonctionnement en mélange pauvre ou dilué. La procédure employée présente la particularité d'associer des outils complémentaires tels que code de calcul tridimensionnel, diagnostics optiques (anémométrie laser et ombroscopie et mesures classiques sur banc monocylindre. La modélisation tridimensionnelle est utilisée comme moyen efficace de sélection et de prédiction de l'aérodynamique interne. Les paramètres les plus influents sur la stabilité de l'initiation de la combustion sont la direction et l'intensité de la vitesse au point d'allumage et le niveau de turbulence. Le meilleur compromis favorable au fonctionnement en mélange pauvre est constitué par une culasse possédant une chambre de combustion en toit avec une seule soupape d'admission. Son aérodynamique interne est caractérisée par la combinaison d'un mouvement de rotation d'axe vertical (swirl avec un tourbillon d'axe horizontal balayant l'arête du toit (tumble. Son niveau de turbulence est ajusté de manière à accroître la vitesse de combustion en limitant les instabilités cycle-à-cycle. La deuxième phase est consacrée à la transposition de cette solution sur un moteur multicylindre. Les principales difficultés rencontrées sont liées aux disparités de comportement entre cylindres accentuées par le fonctionnement en mélange pauvre. Seul un contrôle individuel des paramètres de combustion de chaque cylindre (avance, injection, richesse associé à un écartement d'électrodes de bougie accru permet de re-trouver des résultats proches de ceux acquis sur monocylindre. Dans ces conditions, les limites pauvres se situent à des richesses comprises

  12. Lenna Kuurmaa üllatas / Ode Alt

    Alt, Ode

    2008-01-01

    Rainer Sarneti noortefilm "Kuhu põgenevad hinged?", stsenaariumi aluseks on Aidi Valliku romaanid Annist, kaasstsenarist Peeter Sauter, osades Ragne Veensalu, Lenna Kuurmaa jt. Filmi tootja Exitfilm. Loo autor on Tartu Descartes'i Lütseumi 12. klassi õpilane

  13. A Physics and Tabulated Chemistry Based Compression Ignition Combustion Model: from Chemistry Limited to Mixing Limited Combustion Modes Un modèle de combustion à allumage par compression basé sur la physique et la chimie tabulée : des modes de combustion contrôlés par la chimie jusqu’aux modes contrôlés par le mélange

    Bordet N.

    2011-11-01

    experimental measurements carried out on a 2 liter Renault Diesel engine and good agreements are found. Ce papier présente une nouvelle approche 0D phénoménologique pour prédire le déroulement de la combustion dans les moteurs Diesel à injection directe pour toutes les conditions d’utilisation usuelles. Le but de ce travail est de développer une approche physique en vue d’améliorer la prédiction de la pression cylindre et du dégagement d’énergie, avec un nombre minimum d’essais nécessaires à la calibration. Les contributions principales de cette étude sont la modélisation de la phase de pré-mélange de la combustion et une extension du modèle pour les stratégies d’injections multiples. Dans ce modèle, le taux de dégagement d’énergie dû à la combustion pour la phase pré-mélangée est relié à un taux de réaction moyen du carburant. Ce taux de réaction moyen de carburant est évalué à l’aide d’une approche basée sur un taux de réaction local de carburant tabulé et la détermination d’une fonction de densité de probabilité (PDF de la fraction de mélange (Z. Cette PDF permet de prendre en compte la distribution de richesse existante dans la zone pré-mélangée. L’allure de cette PDF présumée est une β-fonction standardisée. Les fluctuations de la fraction de mélange sont décrites avec une équation de transport pour la variance de Z. La définition standard de la fraction de mélange, établie dans le cas de flammes de diffusion, est ici adaptée à une combustion pré-mélangée de type Diesel pour décrire l’inhomogénéité de la richesse dans le volume de contrôle. La chimie détaillée est décrite au travers de la tabulation du taux de réaction relatif à la flamme principale et du délai d’auto-inflammation relatif à la flamme froide, ces tabulations sont fonction de la variable d’avancement c, du taux de gaz brûlé ainsi que des grandeurs thermodynamiques telles que la température et la pression. Le

  14. Adsorption de l'eau dissoute dans les mélanges supercarburant-alcools en vue de leur stabilisation. Comparaison entre adsorbants classiques et résines échangeuses d'ions Adsorption of Dissolved Water in Premium-Fuel/Alcohol Blends with a View to Their Stabilization. Comparison Between Conventional Adsorbents and Ion-Exchange Resins

    Bernasconi C.

    2006-11-01

    Full Text Available Une réponse possible au problème de la déstabilisation par démixtion des mélanges supercarburant-alcools est l'abaissement de leur teneur en eau par adsorption physique. La forte affinité pour l'eau des résines échangeuses d'ions de type polystyrène sulfonate permet d'envisager leur utilisation dans ce cas spécifique d'application. Le principal intérêt de ce nouveau matériau adsorbant est de pouvoir se régénérer avec des calories de bas niveau (100-120°C. Nous avons donc étudié, du point de vue capacité d'adsorption et cinétique d'adsorption, le comportement de cet adsorbant et comparé ses performances à celles d'adsorbants plus classiques tels que le silicagel, l'alumine et le tamis moléculaire 3 Å. Les formes ioniques de la résine mises en oeuvre sont les formes : K+, Na+ et Mg2+. Sur le plan de la capacité totale d'adsorption, la résine, quelle que soit sa forme ionique, présente des performances supérieures à celles de l'alumine et du silicagel. Seule la forme Mg2+ adsorbe autant d'eau que le tamis moléculaire. L'efficacité de la résine est sensible à la nature de l'alcool du mélange considéré et augmente selon la séquence méthanol A possible answer to the problem of destabilization by the segregation of premium-fuel/alcohol blends lies in decreasing their water content by physical adsorption. The strong affinity of water for ion-exchange resins of the polystyrene sulfonate type suggests their use for this specific application. The main advantage of this newadsorbent material is that it can be regenerated with low-level heat (100-120°C. We thus investigated the behavior of this adsorbent from the standpoint of its adsorption capacity and adsorption kinetics. Its performances were compared to those of more conventional adsorbents, such as silicagel, alumina and a 3Å molecular sieve. The ionic forms of the resin used are in the form of K+, Na+ and Mg2+. From the standpoint of total adsorption capacity

  15. Environmental prices in the long term; Miljoepriser paa lang sikt

    NONE

    1997-12-31

    Economic analyses may undervalue important long-time environmental impacts of economic activities if the calculated price of the impacts are wrong. This report discusses how one may estimate the future calculated price of some environmental services. The term environmental service denotes something the presence or absence of which has an impact on the environment that can be valued. Thus, puffins, NOx emissions and suspended dust are all environmental services. The calculated price of an environmental service is the price used in socio-economic benefit-cost analyses. A calculation method is proposed and evaluated by application to such diverse environmental services as the stock of puffins, impregnated wood, NOx emissions and suspended dust. None of these services are priced in the market. The proposed method can be used to estimate the future prices of environmental services that are not priced in the market. The most important difficulties experienced with the method have been (1) how to find data for the increase in the supply of environmental services and (2) how to define environmental services in a satisfactory way. 29 refs., 5 figs., 6 tabs.

  16. USA dollar langes eile alla 12 krooni / Andris Feldmanis

    Feldmanis, Andris, 1982-

    2004-01-01

    Odavast dollarist kaotavad Eesti ettevõtjatest dollaritsooni eksportijad, võidavad importijad. Skeem: Dollari kurss tagasi 90ndate aastate keskpaiga tasemel. Vt. samas: Tõnis Oja. Ameerikale nõrk dollar meeldib

  17. Waterplanten in poelen langs de Tongelreep bij de Achelse Kluis

    Bruinsma, John

    2007-01-01

    In 1989 zijn zeer voedselrijke landbouwgronden in het dal van de Tongelreep in eigendom overgegaan naar Staatsbosbeheer. Na een periode waarin zonder bemesting nog landbouwgewassen werden verbouwd, zijn de gronden na 1995 braak gelegd en in begrazing genomen, de Tongelreep is vergraven tot een beek

  18. Lang tahab Eestist peletada maailma transiidigigandi / Raimo Poom

    Poom, Raimo

    2009-01-01

    Eesti suurima naftaterminali Vopak E.O.S-i Hollandi omaniku Royal Vopaki kirjast peaminister Andrus Ansipile ja neljale ministrile, milles märgitakse, et plaanitav Tallinna vangla asuks ohtlikke kaupu käitlevate rajatiste suhtes väga suure riskiga tsoonis ning kui vanglale teist asukohta ei leita, lubab firma siia tehtavad investeeringud üle vaadata

  19. Vitale potplanten in lange distributieketens : PT-eindrapport

    Harkema, H.; Westra, E.H.; Otma, E.C.; Boerrigter, H.A.M.

    2012-01-01

    Pot- en perkplantenketens worden langer. Dit komt door de toename van de productie van halfwas en gerede planten in overzeese zuidelijke landen en de draaischijffunctie die Nederland daarbij vervult. De keten wordt ook langer door de ontwikkeling van de Oost-Europese markt. In de nabije toekomst zal

  20. Uventet lang overlevelsestid efter accidentel nedsaenkning i koldt vand

    Mantoni, Teit; Belhage, Bo; Pott, Frank Christian

    2006-01-01

    In a recent boat accident, a 25-year-old yachting enthusiast fell overboard and survived for 24 hours in 17 degrees C water. Existing survival models are discussed in this case report. There is a discrepancy regarding survival probability amongst the various models. The calculated survival time...

  1. Effect of the Aqueous Extract of Gloriosa superba Linn (Langli ...

    Erah

    analysis as well as toxicity (in mice) and antifertility studies, uterotrophic assay, duciduoma model, uterotonic assessment ... The effect of the extract on cardiovascular parameters was also evaluated. .... withheld for 4 h before the drug was.

  2. Legitimatie van de nevengeul voor de Waal langs Varik

    During, R.; Pleijte, M.; Vreke, J.

    2016-01-01

    “Wat is de legitimatie van de geprojecteerde nevengeul van de Waal bij Varik en Heesselt?” In het onderzoek dat heeft plaatsgevonden is specifiek gekeken naar de onderbouwing van de maatgevende afvoer van 18.000 m3/s bij Lobith eind 21e eeuw en naar de wijze waarop er in de planvorming met de

  3. Petrophysical Analysis of Siliceous Ooze Sediments, Ormen Lange Field, Norway

    Awedalkarim, Ahmed; Fabricius, Ida Lykke

    , but apparent porosity indications in any other lithology, such as siliceous ooze, are wrong and they should be corrected. The apparent bulk density log should be influenced by the hydrogen in opal as also the neutron porosity tools because they are sensitive to the amount of hydrogen in a formation...... present in the solid. Some minerals of siliceous ooze, such as opal, have hydrogen in their structures which influences the measured hydrogen index (HI). The neutron tool obtains the combined signal of the HI of the solid phase and of the water that occupies the true porosity. The HI is equal to true...... to interpret lithology and the unusual physical properties of the studied intervals. The integration of all these data revealed that the studied siliceous ooze is a mixture of opal and non-opal (shale). Our results proved to be reasonably consistent. The studied intervals apparently do not contain hydrocarbons....

  4. Narnia täismahus tulemine / Aleks Lange

    Lange, Aleks

    2006-01-01

    Lewis, Clive Staples. Imetegija õepoeg ; Hobune ja tema poiss ; Prints Caspian / tlk. Andry Ervald ; Koiduränduri teekond ; Hõbedane tool ; Viimane lahing / tlk. Aldo Randmaa ; Lõvi, Nõid ja riidekapp / tlk. Andry Ervald ja Maiju Woodhead (Tallinn : Pegasus, 2006. (Narnia kroonikad ; 1-7))

  5. Wetenschapsgeschiedenis op lange termijn: flexibiliteit en fragiliteit van disciplines

    Daan Wegener

    2011-03-01

    Full Text Available Long-term history of science: on the flexibility and fragility of scientific disciplinesMost scientific disciplines, such as chemistry, biology and physics, are now about two centuries old. Using physics as a case study the present paper aims to account for this longevity. What kept the physics discipline together from the early nineteenth century onwards? Literature on the rise of physics suggests that the discipline was formed around energy, the ether, or other theoretical notions. Yet the twentieth-century revolutions in physics showed that the discipline could prosper without some of its most 'fundamental' concepts. Some scholars conclude that internal factors are therefore irrelevant and disciplinary identity and continuity are purely institutional. Drawing on the work of Thomas Kuhn, Peter Galison and Andrew Warwick, this paper defends a different point of view. Although there is no intellectual core of disciplines, the prolonged existence of disciplines cannot be explained without some degree of internal continuity. If there is a revolution of a theoretical level, there may still be continuity on the level of experimental practices (and vice versa. It is this flexibility that accounts for the fact that disciplines may adapt to different circumstances. In addition, an educational tradition is required to transmit knowledge from one generation to the next.

  6. Lange and Hayek revisited: lessons from Czech voucher privatization

    Hanousek, Jan; Filer, Randall K.

    2002-01-01

    Roč. 21, č. 3 (2002), s. 491-498 ISSN 0273-3072 Institutional research plan: CEZ:AV0Z7085904 Keywords : Czech Republic * voucher privatization Subject RIV: AH - Economics http://search. ebscohost .com/login.aspx?direct=true&db=a9h&AN=6463493&site=ehost-live

  7. Etudes physiques des mélanges eau-cryoprotecteurs

    Vassoille, R.; Perez, J.

    The aim of the following review is to present the most important studies concerning the physical properties of water-solutes mixtures used in cryobiology. Cryobiology is a branch of biology which deals with the very low temperature behaviour of cells. This technique is developed today in several directions. The creation of banks of cells and perhaps in a short time of small organs, is the purpose of much research in this domain. Before freezing, living cells are generally put in a solution containing one or more solutes. The role of these solutes is to protect the cells against damage due to crystallization of water (cryoprotectors). The mechanisms of cryoprotection are not well known ; nevertheless the vitreous state formation during cooling is often invoked. So, it is possible to avoid crystallization damage such as mechanical strain (due to an increase of volume of about 10 %) and salt effects (due to osmotic pressure). The conditions in which the vitreous state is obtained, maintained during cooling, storage at low temperature and rewarming can be defined by physical studies presented in the following review. Le présent travail est essentiellement une revue bibliographique des principales études physiques qui ont été réalisées avec des solutions de composés habituellement employés en cryobiologie. La cryobiologie est une branche de la biologie qui s'intéresse au comportement des cellules à basse température. Cette discipline est actuellement en plein développement dans des domaines très divers. Son principal but est la création de banques de cellules de plus en plus complexes avec comme perspective la conservation des organes. Les cellules vivantes sont généralement placées avant congélation dans une solution contenant divers composés dont le rôle est de protéger les cellules contre les effets de la cristallisation de l'eau. L'action protectrice de ces cryoprotecteurs est encore mal connue; cependant, la formation d'un état vitreux lors du refroidissement est souvent invoquée. Ainsi, il est possible d'éviter les dommages liés à la cristallisation : contrainte mécanique due à l'augmentation de volume, effets de sel dus à l'existence d'un gradient de pression osmotique de part et d'autre de la membrane cellulaire. Les conditions d'obtention et de maintien de cet état vitreux lors des opérations de congélation peuvent être définies par des études physiques dont nous proposons une revue.

  8. Lange Vik, Marte. 2015. Landskapsdemokrati som metafor og materialitet

    Arler, Finn; Stenseke, Marie; Setten, Gunhild

    2015-01-01

    Omtale av avhandling for graden philosophiae doctor, juni 2015. Norges teknisk-naturvitenskapelige universitet, Fakultet for samfunnsvitenskap og teknologiledelse, Geografisk institutt. Doktoravhandlinger ved NTNU 2015:284. NTNU, Trondheim. 102 s. + vedlegg. ISBN 978- 82-326-1224-6 (trykt utg.), ...

  9. Lang vej endnu før bilindustrien er Lean

    Christiansen, Thomas Bøhm

    2005-01-01

    Anmeldelse og diskussion af bogen "The Second Century: Reconnecting Customer and Value Chain through Build-to-order - Moving beyond Mass and Lean Production in the Auto Industry......Anmeldelse og diskussion af bogen "The Second Century: Reconnecting Customer and Value Chain through Build-to-order - Moving beyond Mass and Lean Production in the Auto Industry...

  10. Een vrouw met een lang bestaande wond aan haar vinger

    Paulus, Vera A A; Franken, Ralph J P M; van der Heijden, EPA

    2015-01-01

    A 79-year-old woman consulted a plastic surgeon, because since 3 years she had a large wound at the base of her left index finger. Histology of a skin biopsy showed cutaneous squamous cell carcinoma. Because of the extension of the defect, amputation of the index finger with a split-skin-graft was

  11. Geschichte der Sprachenpolitik Kameruns, oder: der lange Weg ...

    Esaïe Djomo. Département de Langues Etrangères Appliquées, Université de Dschang, BP 49 Dschang, Cameroun ... Territorien des Hinterlandes2 kamen viele andere bis dato selbständige kleine Nationen (und damit andere ..... BASAL (Projet de standardisation de base de toutes les langues africaines), begonnen.

  12. Orase õpilasest kirjandusteadlane külastab Eestit / Anne Lange

    Lange, Anne, 1962-

    2007-01-01

    26. jaanuaril toimub Tallinna Ülikooli Akadeemilises Raamatukogus seminar Eesti teadlasest ja tõlkijast Ants Orasest. Seminari korraldavad Tallinna Ülikool ja Eesti Kirjandusmuuseum ning sellel osaleb Oklahoma Ülikooli professor Vincent B. Leitch, kes oli Ants Orase viimaseks juhendatavaks doktorandiks. Vincent B. Leitch vastab artiklis küsimustele, mis puudutavad Ants Orast ja eesti kirjandust

  13. Characteristics of CdLS (Cornelia de Lange Syndrome)

    ... Celebration and Memorial Gifts Planned Giving Monthly Giving Corporate Partnership Matching Gifts Stocks, Trusts and Other Gifts ... 25 percent of individuals with CdLS. Behavioral and communication issues and developmental delays often exist. Major Characteristics ...

  14. Classical cornelia de lange syndrome | Badoe | Ghana Medical ...

    These two case reports illustrate the importance of doing a thorough dysmorphology examination for all so called “Multiple congenital anomalies” children and attempting to fit them into a recognized syndrome. Well over 2000 dysmorphic syndromes are now recognized and diagnosis of these children can be extremely ...

  15. Metode Pengumpulan dan Analisis Data : Lang Kah Vital Proses Penelitian

    Suprapto, Agus .

    2005-01-01

    The process of data collection and. analysis is one of chains in scientific method that should be done in a research. This part later on will determine the right method in searching and analyzing a way in solving a problem. The data collected should be the ones which are relevant which the essence of research problems, so that the next interpreted data will eventually be concluded as valid. keywords: Pengumpulan data, analisis data,dan metode ilmiah

  16. Geschichte der Sprachenpolitik Kameruns, oder: der lange Weg ...

    Even after Independence in 1960, this policy was perpetuated and defended, now by the Cameroonian government who fostered so-called "Official Bilingualism", a policy securing the development of French and English as languages of education, and of administration and general public use in the entire country. The first ...

  17. Smoking reduces circulating CD26hi CD161hi MAIT cells in healthy individuals and patients with multiple sclerosis

    Ammitzbøll, Cecilie; Börnsen, Lars; Romme Christensen, Jeppe

    2017-01-01

    Upon chronic cigarette smoke exposure, inhaled antigens and irritants cause altered lung immune homeostasis. Circulating immune cells are affected, and smoking is associated with an increased risk of developing various disorders, including multiple sclerosis (MS). This study was conducted......-induced proliferation and cytokine secretion in smokers and nonsmokers in a cohort of 100 healthy individuals (HI). In addition, we analyzed immune cell subsets associated with smoking in 2 independent cohorts of patients with MS. In HI smokers compared with nonsmokers, we found increased blood cell counts...... to determine the impact of smoking on circulating immune cell subsets. Furthermore, we determined whether any smoking-associated changes were related to MS. With the use of flow cytometry, CFSE assays, and ELISpot assays, we analyzed circulating immune cell phenotypes and quantified antigen...

  18. Propuesta de programa para una Maestría en Arte e Investigación Teatral (MAIT)

    Prado Zavala, Jorge

    2015-01-01

    En México (y Latinoamérica) ha habido pocos intentos para instrumentar posgrados en teatro, y pocos han persistido. En el pasado en México, la UNAM ya intentó construir un programa de maestría en teatro, pero no prosperó. Algunos estudios prefieren concentrarse en la creación, como el proyecto de Maestría en Dirección Escénica de la ENAT, con un antecedente directo en el CUT. Uno de los intentos más recientes es el programa de Maestría en Teatro de la Universidad Veracruzana, la que a partir ...

  19. Grand Prix' võitis reklaamfilmistuudio Division / Mait Laas, Jaak Lõhmus, Ants Vist...[jt.] ; interv. Tiiu Leis

    1998-01-01

    Pärnu filmipäevadel 'Do Re Vi' võitis Grand Prix ehk skulptuuri 'Oskar & Ella' reklaamistuudio 'Division', kullatud videokassetid said 'Polarfilm' (dok. film), Martin Pedanik (video) ja Edith Sepp ('Tingimustega Tallinnas'); osalejate M. Laasi, J. Lõhmuse, A. Visti ja I. Raagi kommentaare ürituse kohta;

  20. Eesti otsib globaalsel kinnisvaraturul oma kohta. Kas Tallinn on naabritest parim? / Olev Mait Makk ; intervjueerinud Lemmi Kann

    Makk, Olev Mait

    2011-01-01

    Intervjuu Cannes'is globaalsel kinnisvaramessil ja konverentsil MIPIM 2011 viibinud Seven Real Estate Advisors partneri, investeeringute ja nõustamisvaldkonna juhiga. Kinnisvara puhul on välisinvestorite poolt eelistatud sihtriik nn. uue Euroopa riikide seas Poola. Välisinvestorite suurim huvi Eestis on stabiilset rahavoogu tootvate büroo- ja kaubanduskeskuste vastu

  1. Tugeva kultuuriga firmas võetakse vastutust, nõrgas süüdistatakse teisi / Mait Raava

    Raava, Mait

    2005-01-01

    Ilmunud ka: Delovõje Vedomosti 12. okt. lk. 39; Juhi ideelaegas. - Tallinn, 2006, lk. 10-13. Tugev organisatsioonikultuur suunab töötajaid raskuste korral pingutama, nõrk firmakultuur aga iseenda tagalat kindlustama ja teisi süüdistama

  2. 2013. aasta preemiate žürii kommentaar = Comments from 2013 annual prize panel of judges / Mait Väljas

    Väljas, Mait

    2015-01-01

    Eesti kultuurkapitali aastapreemia 2013 Tartu Ülikooli Narva Kolledžile. Arhitektuuri sihtkapitali arhitektuuripreemia Viljandi Riigigümnaasiumile, arhitektuuri eripreemia Kukemõisa karjamõisale, sisearhitektuuripreemia Tallinna Ülikooli BFMi õppehoonele, maastikuarhitektuuripreemia Eesti Ajaloomuuseumi väliekspositsioonile "Klooga laager ja holokaust", innovatsioonipreemia Passion House moodulmajale, arhitektuurialase tegevuse preemia Triin Ojarile ja disainipreemia Matti Õunapuule roller Stigo eest

  3. Selles töös oli kaks õudust : vangla ja tants / Mait Malmsten ; interv. Tiina Ansip

    Malmsten, Mait

    2005-01-01

    Näitleja räägib oma tööst ja rollist rahvusvahelises ühistöös valminud tantsufilmis "Teine" ("Another") : režissöör Rene Vilbre : koreograaf ja peaoaline Helena Jonsdottir. Filmi võtted toimusid Tartu vanglas

  4. Kangelane ja kaabakas: kuulsad kuningad muistse LähisIda ja Kreeka pärimustes / Mait Kõiv

    Kõiv, Mait, 1961-

    2015-01-01

    Mesopotaamia, Pärsia ja Vana-Kreeka kolmest olulisest dünastiast. Akkadi kuningatest - Sargon'ist ja Naram-Sin'ist, Pärsia kuningatest Kyros'est ja Kambyses'est. Korintose türannidest Kypselos'est ja Periandros'est. Pärimuse tagamaadest: müütidest, propagandast ja reaalsusest. Dünastia rajaja kujutamisest kangelasena ja dünastia viimase esindaja demoniseerimisest

  5. Impact of screens on air quality. Final report of a study on the performance of (sound)screens on the air quality along highways; Invloed schermen op de luchtkwaliteit. Eindrapport onderzoek naar de werking van (geluids)schermen op de luchtkwaliteit langs snelwegen

    Van Blokland, G.; Hooghwerff, J.; Tollenaar, C. [M en P Raadgevende Ingenieurs, Aalsmeer (Netherlands)

    2009-12-15

    4 m barrier stays the same during the whole programme and at other cross sections modified designs were tested. Although testing of barrier efficiency for air quality is subjected to sources of error, after prolonged measuring time and correcting for known systematic deviations, results could be presented. At a distance of 10 m behind the (standard) barrier, the reduction effect for NO2 is 14 ({+-}10)%, for NOx 20({+-}6)% and for PM10 34({+-}25)% (values between () indicate 95% confidence interval). The test was not able to detect any systematic improvement of the innovative barrier designs relative to the standard barrier, data could even indicate lower performance. In parallel the quality of measurement and calculation tools was studied by a roundrobin- test of CFD based calculations and of wind tunnel testing of a few specific situations. Results for both the CFD-calculations and the round-robin-test of wind tunnels will be presented in a separate report. One may conclude that within the frame work of the IPL barrier research program a vast amount of very relevant data is produced and very valuable findings were established. We must conclude however that there still remains a lot of unanswered questions that shall be considered to be of importance when applying barriers on a wider scale for air quality reasons. At the present state the implementation of innovative barriers for air quality cannot be done to its full potential. [Dutch] In de periode 2005 tot en met 2009 is een onderzoeksprogramma uitgevoerd naar de effecten van (geluid)schermen op de luchtkwaliteit langs de weg en zijn nieuwe systemen ontwikkeld om de effectiviteit voor de luchtkwaliteit van de schermen te verbeteren. Daarnaast is aandacht besteed aan de vergelijkbaarheid en betrouwbaarheid van het reken- en meetinstrumentarium waarmee de effecten berekend en gemodelleerd kunnen worden. Er werd op basis van buitenlands onderzoek al een zekere mate van effectiviteit van schermen verondersteld en de

  6. Récupération des hydrocarbures des pieds de bacs provenant de la démixtion des mélanges méthanol-supercarburant. Application du procédé de séparation par coalescence Recovery of Hydrocarbons from Bottoms of Storage Tanks Coming from the Demixing of Methanol/Premium-Gasoline Blends. Application of the Coalescence-Separation Process

    Hoornaert P.

    2006-11-01

    Full Text Available Une solution technique et économique a été mise au point pour traiter les pieds de bacsprovenant de la démixtion de mélanges méthanol - supercarburant au contact de traces d'eau. Le procédé consiste à provoquer une deuxième démixtion par addition d'eau à la phase à traiter. Les hydrocarbures ainsi relargués sont séparés parfaitement en utilisant un coalesceur à résines oléophiles. Il est ainsi possible de récupérer et de recycler la quasi-totalité des hydrocarbures contenus dans lespieds de bacs . L'effluent aqueux résiduel chargé en alcool peut, soit être recyclé, soit traité par la station de traitement d'eaux de la raffinerie. A technical and economic solution has been developed for processing bottoms of storage tankscoming from the demixing of methanol/premium-gasoline blends in contact with traces of water. The process consists in producing a second demixing by the addition of water to the phase to be processed. The hydrocarbons thus salted out are effectively separated by an oleophilic-resin coalescer. In this way almost all of the hydrocarbons contained in the bottoms of storage tankscan be recovered and recycled. The residual aqueous effluent containing alcohol can either be recycled or processed by the waste-water treatment station of the refinery.

  7. Vinyl Sulfonate/Vinyl Amide Copolymers and Different Surfactants As Suitable Systems in Eorat Higher Temperatures and Salinities Utilisation de mélanges de copolymères vinyl sulfonate/vinyl amide et de différents tensio-actifs en RAP dans des conditions de fortes salinités et de températures élevées

    Von Halasz S. P.

    2006-11-01

    propriétés des solutions de copolymères VS/VA/AM. Des solutions aqueuses de ces copolymères ont été ajoutées à des quantités variables de tensio-actifs non ioniques et anioniques dans différentes conditions de température et de salinité. Les résultats de tests de compatibilité, de pouvoir viscosifiant, de comportement en milieu poreux, d'injectivité, de dégradation mécanique, de stabilité thermique et de récupération d'huile de ces différents mélanges sont présentés et discutés. La présence de polymère influence peu les propriétés des solutions d'alkylphénols éthoxylates et/ou d'éthers sulfonates dans une large gamme de températures et de salinités. Par contre, des quantités relativement faibles de tensioactifs peuvent modifier sensiblement le comportement des solutions de polymères et améliorer leur efficacité en RAP (Récupération Assistée du Pétrole.

  8. Näitlejad ühes mullis, esietendus ukse ees / Hendrik Toompere jr. jr., Liisa Pulk, Mait Joorits ... [jt.] ; intervjueerinud Liisi Seil ; kommenteerinud Helle Leppik

    2010-01-01

    Vestlus Eesti muusika- ja teatriakadeemia lavakunstikooli XXIV lennu tudengitega, kelle lõputöö Tom Stoppardi näidend "Arkaadia" etendub Ugala laval. Lisatud Ugala teatri kirjandustoimetaja arvamus

  9. Tasakaalus tulemuskaardi sage viga on vääralt määratud näitajad / Mait Raava

    Raava, Mait

    2003-01-01

    Tasakaalus tulemuskaart väljendab strateegiliste tulemusnäitajate põhjuslik-tagajärjelisi seoseid, kuid viga tuleb sageli nende tegurite määratlemisel, kirjutab autor. Skeem. Kommenteerib Sven Heil

  10. Ühe novelli lugu : subjektiivne kirjanduslooline etüüd / Aivar Kull

    Kull, Aivar, 1955-

    2015-01-01

    Mait Metsanurga pikemast novellist "Dora Praats", mis ilmus 1943. a. vene keeles; avaldatud ka 16-osalise järjejutuna Toronto ajalehes "Vaba Eestlane" (8. veebr. - 2. aprill 1958) ning Mait Metsanurga novellikogumikus "Kreeps" (Tallinn : Eesti Raamat, 2005)

  11. Causal Relationships Among Time Series of the Lange Bramke Catchment (Harz Mountains, Germany)

    Aufgebauer, Britta; Hauhs, Michael; Bogner, Christina; Meesenburg, Henning; Lange, Holger

    2016-04-01

    Convergent Cross Mapping (CCM) has recently been introduced by Sugihara et al. for the identification and quantification of causal relationships among ecosystem variables. In particular, the method allows to decide on the direction of causality; in some cases, the causality might be bidirectional, indicating a network structure. We extend this approach by introducing a method of surrogate data to obtain confidence intervals for CCM results. We then apply this method to time series from stream water chemistry. Specifically, we analyze a set of eight dissolved major ions from three different catchments belonging to the hydrological monitoring system at the Bramke valley in the Harz Mountains, Germany. Our results demonstrate the potentials and limits of CCM as a monitoring instrument in forestry and hydrology or as a tool to identify processes in ecosystem research. While some networks of causally linked ions can be associated with simple physical and chemical processes, other results illustrate peculiarities of the three studied catchments, which are explained in the context of their special history.

  12. Séparation Aveugle de Mélanges Convolutifs de Sources

    Boumaraf , Hakim

    2005-01-01

    In this thesis, Blind Source Separation (BSS) of Convolutive Mixtures of Sources is addressed. For separating audio mixtures, we have developed new methods for cases without noise and with noise in propagation environment. The method for case without noise is based on joint diagonalization of spectral matrices and exploit the non stationarity of signals. We have proposed two techniques in order to solve permutation problem. The second method where an additive noise is present, is based on max...

  13. Viru keskuse omanik SRV langes Venemaal suure kahju osaliseks / Andres Eilart

    Eilart, Andres

    2007-01-01

    Taani firma Nordrus Hotel Holdings keeldus Soome ehitusfirmalt SRV, mis on Viru keskuse põhiomanik, vastu võtmast Jekaterinburgi ehitatud hotellikompleksi. SRV on kohustatud maksma kahjutasu kokku 13,2 mln. dollarit

  14. Fossil fields of Ilmandu and Muraste north Estonia / Valter Lang, Helena Kaldre, Marge Konsa...[jt.

    2004-01-01

    Imandu ja Muraste küla maadel on plaanistatud seni kõige suurem fossiilsete põldude jäänustega ala Eestis. Esindatud on eri tüüpi põllusüseemid. Maaharimise alguse neil aladel võib dateerida eelrooma rauaaega ning see kestis kuni uusajani

  15. New Investigations at Fossil Fields of Proosa, North Estonia / Valter Lang, Margot Laneman

    Lang, Valter, 1958-

    2006-01-01

    Proosa fossiilsed põllud avastati 1992. aastal. Pärast osa maa erastamist firmale Loo Auto OÜ lükati seal buldooseriga ära kogu paepõhja kattev pinnas, millega hävitati kõik jäljed kunagisest põlluharimisest. Päästeuuringutest 2005. aastal

  16. The pathogenic fungi in mushroom cultivation of Agaricus bisporus (Lange.) Imbach.

    Agata Tekiela

    2012-01-01

    The research was conducted in a mushroom growing facility located near Rzeszów, consisting of three production cycles. The number and composition of microorganisms which accompany the mushroom cultivation depended on the healthiness of: the compost, casing and spawn of Agaricus bisporus. The presence of pathogenic fungi in the cultivation halls at the beginning of the production cycle is a serious threat to the cultivation of common mushroom because their rapid development shortens the span o...

  17. The pathogenic fungi in mushroom cultivation of Agaricus bisporus (Lange. Imbach.

    Agata Tekiela

    2012-12-01

    Full Text Available The research was conducted in a mushroom growing facility located near Rzeszów, consisting of three production cycles. The number and composition of microorganisms which accompany the mushroom cultivation depended on the healthiness of: the compost, casing and spawn of Agaricus bisporus. The presence of pathogenic fungi in the cultivation halls at the beginning of the production cycle is a serious threat to the cultivation of common mushroom because their rapid development shortens the span of fruiting body harvests.

  18. Når muskelrelaxantia har uventet lang virkningsvarighed under anæstesi

    Madsen, Matias Vested; Øberg, Emilie; Rosenberg, Jacob

    2015-01-01

    Muscle relaxation facilitates tracheal intubation and improves surgical conditions during anaesthesia. However, unexpected prolonged muscle relaxation may occur. This article describes important causes of prolonged muscle relaxation and gives suggestions for its prevention. Drug interactions, inc......, incomplete reversal, co-morbidity, inaccurate neuromuscular monitoring and critical illness may prolong the effect of muscle relaxants. The anaesthetist must titrate the muscle relaxants using objective neuromuscular monitoring and proper reversal of the blockade when needed....

  19. Nederlandse consumptie en energiegebruik in 2030, een verkennende basis van twee lange termijn scenario's

    Vringer K; Aalbers TG; Drissen E; Hoevenagel R; Bertens CAW; Rood GA; Ros JPM; Annema JA; LAE

    2001-01-01

    Major issues in the Dutch fourth National Environmental Policy Plan are sustainability and quality of life. The energy requirement for consumption tripled between 1948 and 1996. In this period no significant trends towards a lower energy intensity were found and there is no indication of

  20. De samenhang tussen prenatale blootstelling aan de Hongerwinter en medische bevindingen op lange termijn

    Roseboom, T. J.; van der Meulen, J. H.; Ravelli, A. C.; Bleker, O. P.

    2000-01-01

    The 'foetal origins' hypothesis (Barker hypothesis) proposes that undernutrition of the foetus during critical periods of development increases the risk of coronary heart disease in later life. The Dutch famine caused by the second World War in the winter of 1944--although a historical

  1. Youth labour market integration across Europe / Marloes de Lange, Maurice Gesthuizen, Maarten H. J. Wolbers

    de Lange, Marloes

    2014-01-01

    Artiklis analüüsitakse, mil määral seletavad tsüklilised, struktuursed ja institutsionaalsed tegurid Euroopa Liidu liikmeriikide (sh Eesti) vahelisi erinevusi noorte tööhõives, aluseks Euroopa sotsiaaluuringud

  2. Cornelia-de Lange syndrome in an Egyptian infant with unusual ...

    ... metacarpophalengeal joints, bilateral short big toes, angulation of the lower part of the bones of right forearm and both legs with multiple skin folds. Also biochemical and X-ray evidence of rickets was detected mostly due to malnutrition and failure to thrive. The patient died at the age of 5 months with bronchopneumonia

  3. Cornelia-de Lange syndrome in an Egyptian infant with unusual ...

    Rabah M. Shawky

    2012-05-18

    May 18, 2012 ... Also biochemical and X-ray evidence of rickets was detected mostly due to ... Chest examination showed small chest, depressed lower sternum ... teal erosion was noted at the medial aspect of the femur, and there was an ...

  4. Anna Maria Jordan: Entgeltdiskriminierung in Frauenberufen? Frankfurt am Main u.a.: Peter Lang Verlag 2012.

    Andrea Jochmann-Döll

    2013-10-01

    Full Text Available Die Ursachen für die statistisch feststellbaren Entgeltunterschiede zwischen Frauen und Männern sieht Jordan überwiegend in autonomen Entscheidungen von Frauen, die zum Teil durch traditionelle familiäre Strukturen und alte Rollenmuster beeinflusst werden; hinzu kommen diskriminierende Tendenzen auf Seiten der Arbeitgeber. Zur Verringerung der Entgeltlücke werden die bestehenden familienpolitischen Maßnahmen des Staates und Initiativen zur Erweiterung des Berufswahlspektrums von Frauen und Männern begrüßt. Darüber hinaus schlägt Jordan allgemeine Mindestlöhne und Frauenquoten für gewerkschaftliche Führungspositionen vor. Eine gerichtliche Überprüfbarkeit des Prinzips des gleichen Entgelts für gleichwertige Arbeit wird jedoch abgelehnt, da sich der Wert von Arbeit nicht objektiv bestimmen lasse.Jordan sees the reasons for the statistically detectable differences in remuneration between women and men mainly in autonomous decisions by women, who are in parts influenced by traditional family structures and old role models, paired with discriminating tendencies on the employer side. Jordan appreciates the state’s existing family political measures as well as initiatives that aim at expanding the range of career choices of women and men. Furthermore, Jordan suggests general minimum wages and female quotas for union managerial positions. However, the author rejects a legal verifiability of the principle of equal pay for equal work since the value of work cannot be determined objectively.

  5. Pipe conveyors transport bulk material efficiently over long distances; Rohrgurtfoerderer transportieren Schuettgut effizient ueber lange Strecken

    Will, Frank [BEUMER Maschinenfabrik GmbH und Co. KG, Beckum (Germany); Staribacher, Josef [KOCH Material Handling GmbH, Schwechat (Australia)

    2011-05-15

    The specific characteristics of a pipe conveyor, which are due to its operating principle, allow transportation solutions which are not possible with other conveyor systems; or if they are possible, then only with considerable restrictions or additional expenses. The enclosed design of the pipe conveyor protects the material from the environment and the environment from the conveyed material. The system, thus, makes a valuable contribution towards achieving environmental protection objectives and in meeting official regulations. The pipe conveyor handles both tight curve radiuses and steep inclines. This permits a very flexible route and also allows existing obstacles to be bypassed. Consequently, solutions can often be found which do not require any changes to be made to the existing terrain or plant structures. The investment costs of just the conveyor can sometimes be slightly higher for a pipe conveyor than for a conventional troughed belt conveyor. But if the pipe conveyor can take full advantage of its special features, then these additional costs become quite relative very quickly. And if, for example, transfer points, alterations of existing facilities, earthwork, or expensive dust and noise protection measures can be avoided due to the very flexible route layout of the pipe conveyor, then these savings on part of the customer are much higher than the additional costs for this perfect conveyor system. All told, it is possible to solve challenging conveying tasks with great efficiency while also saving resources when the pipe conveyor is used; thus, producing a sustained benefit to both the operator and the environment. (orig.)

  6. Txt Lang: Texting, Textism Use and Literacy Abilities in Adolescents with and without Specific Language Impairment

    Durkin, K.; Conti-Ramsden, G.; Walker, A. J.

    2011-01-01

    The present study examined text messaging in adolescence, in particular relationships among textism use, language and literacy skills. Forty-seven typically developing (TD) 17-year-olds and 47 adolescents of the same age with specific language impairment (SLI) participated. Participants completed standardised assessments of cognitive, language and…

  7. Variability of GPS Radio Sources at 5 GHz Lang Cui , Xiang Liu ...

    2010-02-07

    Feb 7, 2010 ... Abstract. We carry out flux monitoring on a sample of 169 Gigahertz. Peaked Spectrum (GPS) radio sources at 5 GHz and find that about one- third of them show considerable Inter-Month Variability (IMV), and these. IMV phenomena are likely to be caused by interstellar scintillation (ISS). Furthermore, we ...

  8. Patienttilfredshed efter hofte- og knaealloplastik med kort vs. lang indlaeggelse. III

    Husted, Henrik; Hansen, Hans Christian; Holm, Gitte

    2006-01-01

    The goal of this study was to evaluate patient satisfaction with the hospital stay in relation to the length of stay for patients operated on with primary total hip- and knee-arthroplasty (THA and TKA)....

  9. Hvilke varige skadevirkninger har lang tids bruk av cannabis på kognitive funksjoner.

    Olsen, Knut Marius

    2007-01-01

    Abstract Background: Cannabis is the world’s most commonly used illicit drug, being used of about 4 % of the total global population between 15 and 64 years of age. After the discovery of the endocannabinoid system there has been an increase in the research about cannabis and THC and its potential use as a therapeutical drug. Hence there has also been renewed interest in its possible negative effects. Aims: To highlight recent knowledge and literature about the possible non-...

  10. Tim Lang and Michael Heasman, Food Wars. The Global Battle for Mouths, Minds and Markets

    Virginie Amilien

    2005-05-01

    Full Text Available Food wars can be understood as a war declaration against nowadays food-world. This book is full of images for a sustainable world which is opposition with the social and economic unfair society we live in. The authors propose quite concrete solution for a new food policy and draw a new frame for food policy and public health.Core arguments are simple: “Food policy is in crisis, in particular over health.” The unique model of food supply we have followed the last 50 years cannot continue that ...

  11. Utilization and development of the portable prototype equipment of lang inhalation with radioactive aerosols

    Marroni, B.J.; Siegmann, W.

    1986-01-01

    The 99 Tc-Aerosol was obtaneid from coloidal substances using a new apparatus, the 'Aerogama'. This equipment uses a conventional nebulyzer, an O 2 source, a respiratory system with inspiratory/expiratory compartments that are connected by valves and tubes with a one way flow. The environment contaminations is minimal and the 140 KeV energy rays are attenuated in about 93%. It has high utility in nuclear medicine as diagnostic tool applied to some lung diseases. (Author) [pt

  12. Sustainable Lang Use in Hilly Red Soil Region of Southeastern China

    ZHANGTAO-LIN; ZHAOQI-GUO; 等

    1995-01-01

    In the present work,an integrated analysis of natural and socio-economic conditions in the hilly red soil region of southeastern China is made by means of a Geographic Information System.Particular emphasis lies on soil degradation and other adverse ecological and environmental effects of the prevalent and irrational land-use systems of mono-and valley-agriculture in the region.Moreover,taking into account the simultaneous existence of enormous potentials and serious constraints and the high diversity and complexity of the biophysical and socio-economic environments,a set of strategies and countermeasures are also proposed for appropriate management of environmental resources,in terms of maintaining harmony between utilization and coservation of the natural environment,including 1) adjustment of the agricultural structure and optimization of ecological patterns of stereo-agriculture;2) improvement and integrated exploitation of the low-yield lands and wastelands;3) ehabilitation and conservation of soil and water resources;and 4) establishment of production bases of tropical and subtropical cash crops and fruits.

  13. Air quality along motorways. Measuring and modelling calculations; Luftkvalitet langs motorveje. Maelekampagne og modelberegninger

    Solvang Jensen, S.; Loefstroem, P.; Berkowich, R.; Roerdam Olsen, H.; Frydendall, J. [DMU, Afd. for Atmosfaerisk Miljoe, Roskilde (DK); Fuglsang, K. [FORCE Technology, Broendby (Denmark); Hummelshoej, P. [MetSupport, Roskilde (Denmark)

    2004-12-01

    This report describes the air quality along Koege Bugt motorway, one of the most trafficked sections in Denmark. A number of measurements have been carried out along Koege Bugt motorway at Greve for a three-month period in the autumn of 2003. For the first time in Denmark, NO{sub x} were measured with high time dissolution from different distances of the motorway. Furthermore, a number of meteorological parameters were measured in order to map local meteorological conditions. An air quality model describing dispersal and conversion has been made on the basis of the OML model. The OML model is modified in order to take traffic-made turbulence into consideration. The model has been evaluated through comparisons between measurements and simulated calculations. Furthermore, simulated calculations for the year 2003 has been made for comparison with extreme values. (BA)

  14. Cornelia-de Lange syndrome in an Egyptian infant with unusual ...

    Rabah M. Shawky

    2012-05-18

    May 18, 2012 ... in the right upper limb and both lower limbs dating since birth. There was no family history of a ... ECHO cardiography showed mild left pulmonary artery branch stenosis. .... MRI of the brain in our patient demonstrated brain atro- phy. ... the exact function of the protein product of NIPBL in humans. (delangin) ...

  15. Ethnobotanical knowledge of the Kuy and Khmer people in Prey Lang, Cambodia

    Turreira Garcia, Nerea; Argyriou, Dimitrios; Chhang, Phourin

    2017-01-01

    Indigenous peoples and forest-dependent communities are known to hold unique knowledge on natural resources in their surrounding environment. However, environmental degradation has diminished the availability of natural resources and threatens the bio-cultural survival of indigenous and local peo...

  16. Anders polderen – Lange termijn hervormingsbeleid in de veel-partijen-overlegeconomie

    Hemerijck, A.C.

    2016-01-01

    Dutch socioeconomic concertation has experienced some transformative changes in its modus operandi in recent years, which has given the 'Polder Model' a new lease on life for the time being. Building on an older tradition of sharing political space with civil society organizations, the recent

  17. Lange termijneffecten van jeugdparticipatie : Persistente effecten van deelname aan jeugdverenigingen in Nederland en de Verenigde Staten

    Bekkers, René; Hooghe, Marc; Stolle, Dietlind

    2004-01-01

    Gelet op het belang van primaire socialisatieprocessen, kan men van de verwachting uitgaan dat participatie in jeugdverenigingen persistente effecten zal hebben op latere gedrags- en attitudinale actoren. Deze effecten kunnen zowel verklaard worden vanuit een sociale integratie- (interiorisatie van

  18. Verhalen sprokkelen langs de frontlijn. Een kritische blik op Ten Oorlog

    Hans Boers

    2015-03-01

    Full Text Available Gathering Stories along the Front: A Critical Look at Ten Oorlog [To War]This article reflects critically on the popular television programme Ten Oorlog, thereby examining the field of tension between history and entertainment, between historians and ‘the public’. History can be addressed via various television formats as an historical documentary or a travel programme. An analysis indicates the extent to which Ten Oorlog is inspired by these formats. However, the popular television programme from the outset was not conceived as a classic historical documentary and perhaps can best be described as a historical human interest programme as part of the large-scale commemoration of the First World War. How do history and entertainment relate to one another in this programme? Is there more emphasis on the historical context or on anecdotal stories? This analysis of Ten Oorlog illustrates the tense relation between historians and ‘the public’.Dit artikel werpt een kritische blik op het populaire televisieprogramma Ten Oorlog en gaat daarbij in op het spanningsveld tussen geschiedenis en entertainment, tussen historici en ‘het publiek’. Geschiedenis kan via verschillende formats zoals een historische documentaire of een reisprogramma aan bod komen op televisie. Een analyse van deze formats geeft aan in welke mate Ten Oorlog hierop geïnspireerd is. Het populaire televisieprogramma was echter van begin af aan niet als een klassieke historische documentaire bedoeld en kan misschien het bestomschreven worden als een historisch human interest programma, in het kader van de grootschalige herdenking van de Eerste Wereldoorlog. Hoe verhoudengeschiedenis en entertainment zich daarin? Helt de balans meer over naar historische omkadering of naar anekdotische verhalen? Deze analyse van Ten Oorlog illustreert de gespannen relatie tussen historici en het grote publiek.

  19. ’Den lange rejse …‘ - metaforiske betydningslag og branding i filmmediet

    Petersen, Christine; Engerer, Volkmar Paul

    2014-01-01

    This article investigates the implicit metaphorical meanings and motifs in a short campaign film and analyses the ways in which the narrative and sequential structure of the film unfolds itself in order to generate these underlying layers of meanings. The short film ‘Tænk. Hvis det er dig’ (‘Thin...... to an in-depth understanding of visually-based cinematic and narrative techniques.......This article investigates the implicit metaphorical meanings and motifs in a short campaign film and analyses the ways in which the narrative and sequential structure of the film unfolds itself in order to generate these underlying layers of meanings. The short film ‘Tænk. Hvis det er dig’ (‘Think...... for an interpretation of the underlying narrative metaphor as ‘education as a modern Grand Tour’ – a metaphor that connotes (often culturally-anchored) concepts and notions such as ‘general education’ (Bildung, which includes academic knowledge and skills as well as the notion of the university as a social context...

  20. Aanbevelingen voor de verlichting van lange tunnels voor het gemotoriseerde wegverkeer.

    Schreuder, D.A.

    1990-01-01

    Recommendations for Tunnel lighting presented here concern the principles which underlie to the lighting of long tunnels for motorised traffic. They present photometric specifications by which an effective tunnel lighting can be obtained, taking into account traffic safety, traffic flow and driving

  1. Bodemkundig onderzoek in een aantal percelen langs de gasleiding in Meeden (Gr.)

    Heuveln, van B.

    1967-01-01

    In het najaar van 1965 heeft de N.V. Nederlandse Aardolie Maatschappij een gasleiding gelegd, o.m. door het dorp Meeden. Op de percelen is voor het leggen bronbemaling toegepast. De grondeigenaren stellen, dat door deze bronbemaling mogelijk schade is toegebracht aan hun landerijen.

  2. Ettevõtte saab pankroti asemel uuesti jalule tõsta / Rein Lang

    Lang, Rein, 1957-

    2008-01-01

    Seaduseelnõust, millega luuakse makseraskustesse sattunud firmade jaoks saneerimismenetlus, mis on alternatiiv senisele pankrotimenetlusele. Ilmunud ka Sakala 29. juuli 2008, lk. 2, pealkiri kujul: menetlus aitab makseraskustes ettevõtte jalule ; Pärnu Postimees 30. juuli 2008, lk. 15 ; Põhjarannik 29. juuli 2008, lk. 2 ; Võrumaa Teataja 31. juuli 2008, lk. 2 ; Koit 31. juuli 2008, lk. 6 ; Kuulutaja 1. august 2008, lk. 4 ; Nädaline 5. aug. 2008, lk. 4 ; Oma Saar 5. aug. 2008, lk. 5

  3. Leve lang leren : het effect van een positieve leerervaring op de self-efficacy van laagopgeleiden

    Damen, M.A.W.; Sanders, J.M.A.F.; Dam, K. van

    2013-01-01

    For both public authorities, businesses and employees ‘life-long learning’ remains increasingly important to maintain their competitive position in relation to other players on the world market and labor market respectively. Life-long learning, however, is not self-evident for everyone. Lower

  4. Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity.

    Kwon, Yong-Soo; Cho, Young-Nan; Kim, Moon-Ju; Jin, Hye-Mi; Jung, Hyun-Ju; Kang, Jeong-Hwa; Park, Ki-Jeong; Kim, Tae-Jong; Kee, Hae Jin; Kim, Nacksung; Kee, Seung-Jung; Park, Yong-Wook

    2015-05-01

    Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections. The aims of this study were to examine the levels of MAIT cells in pulmonary tuberculosis (TB) and nontuberculous mycobacteria (NTM) lung disease patients, to evaluate the clinical relevance of MAIT cell levels, and to investigate the functions of MAIT cells. Patients with pulmonary TB (n = 35), NTM (n = 29), and healthy controls (n = 75) were enrolled in the study. MAIT cell levels and functions were measured by flow cytometry. Circluating MAIT cell levels were found to be reduced in TB and NTM patients. MAIT cell deficiency reflects a variety of clinical conditions. In particular, MAIT cell numbers were significantly correlated with sputum AFB positivity, extent of disease, hemoglobin levels, lymphocyte counts, CRP and ESR levels. MAIT cells in TB patients failed to produce interferon-γ irrespective of the mode of stimulation, whereas NTM patients displayed a defect in MR1-dependent signaling pathway. Notably, an elevated expression of programmed death-1 was also associated with MAIT cell deficiency in TB. This study shows that MAIT cells are numerically and functionally deficient in TB and NTM patients and these deficiencies could contribute to immune system dysreguation in mycobacterial infection. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Maximal exercise increases mucosal associated invariant T cell frequency and number in healthy young men.

    Hanson, Erik D; Danson, Eli; Nguyen-Robertson, Catriona V; Fyfe, Jackson J; Stepto, Nigel K; Bartlett, David B; Sakkal, Samy

    2017-11-01

    Mucosal associated invariant T (MAIT) cells have properties of the innate and acquired immune systems. While the response to vigorous exercise has been established for most leukocytes, MAIT cells have not been investigated. Therefore, the purpose was to determine if MAIT cell lymphocytosis occurs with acute maximal aerobic exercise and if this response is influenced by exercise duration, cardiovascular fitness, or body composition. Twenty healthy young males with moderate fitness levels performed an extended graded exercise test until volitional fatigue. Peripheral blood mononuclear cells were isolated from venous blood obtained prior and immediately after exercise and were labeled to identify specific T cell populations using flow cytometry. The percentage of MAIT cells relative to total T cells significantly increased from 3.0 to 3.8% and absolute MAIT cell counts increased by 2.2-fold following maximal exercise. MAIT cell subpopulation proportions were unchanged with exercise. Within cytotoxic T lymphocytes (CTL), MAIT cells consisted of 8% of these cells and this remained constant after exercise. MAIT cell counts and changes with exercise were not affected by body composition, VO 2peak , or exercise duration. Maximal exercise doubled MAIT cell numbers and showed preferential mobilization within total T cells but the response was not influenced by fitness levels, exercise duration, or body composition. These results suggest that acute exercise could be used to offset MAIT cell deficiencies observed with certain pathologies. MAIT cells also make up a substantial proportion of CTLs, which may have implications for cytotoxicity assays using these cells.

  6. Lugemisnoppeid: antropoloogia / Marek Tamm

    Tamm, Marek, 1973-

    2012-01-01

    Tutvustus: Jürgenson, Aivar. Ladina rahva seas : Argentina ja sealsed eestlased. Tallinn, 2011 ; Annist, Aet. Otsides kogukonda sotsialismijärgses keskuskülas : arenguantropoloogiline uurimus. Tallinn : Tallinna Ülikooli Kirjastus, 2011. (Acta Universitatis Tallinnensis. Socialia) ; Hiiemäe, Reet. Kaitsemaagia eesti rahvausundis. Tallinn, 2012 ; Augé, Marc. Kohad ja mittekohad : sissejuhatus ülimodernsuse antropoloogiasse. Tallinn : Tallinna Ülikooli Kirjastus, 2012. (Bibliotheca controversiarum)

  7. Activation, Impaired Tumor Necrosis Factor-α Production, and Deficiency of Circulating Mucosal-Associated Invariant T Cells in Patients with Scrub Typhus.

    Kang, Seung-Ji; Jin, Hye-Mi; Won, Eun Jeong; Cho, Young-Nan; Jung, Hyun-Ju; Kwon, Yong-Soo; Kee, Hae Jin; Ju, Jae Kyun; Kim, Jung-Chul; Kim, Uh Jin; Jang, Hee-Chang; Jung, Sook-In; Kee, Seung-Jung; Park, Yong-Wook

    2016-07-01

    Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections. However, little is known about the role of MAIT cells in Orientia tsutsugamushi infection. Hence, the aims of this study were to examine the level and function of MAIT cells in patients with scrub typhus and to evaluate the clinical relevance of MAIT cell levels. Thirty-eight patients with scrub typhus and 53 health control subjects were enrolled in the study. The patients were further divided into subgroups according to disease severity. MAIT cell level and function in the peripheral blood were measured by flow cytometry. Circulating MAIT cell levels were found to be significantly reduced in scrub typhus patients. MAIT cell deficiency reflects a variety of clinical conditions. In particular, MAT cell levels reflect disease severity. MAIT cells in scrub typhus patients displayed impaired tumor necrosis factor (TNF)-α production, which was restored during the remission phase. In addition, the impaired production of TNF-α by MAIT cells was associated with elevated CD69 expression. This study shows that circulating MAIT cells are activated, numerically deficient, and functionally impaired in TNF-α production in patients with scrub typhus. These abnormalities possibly contribute to immune system dysregulation in scrub typhus infection.

  8. Etude des huiles et des mélanges à base d'huile minérale pour transformateurs de puissance – Recherche d'une mélange optimal

    Perrier , Christophe

    2005-01-01

    Mineral oil is the most commonly used insulating liquid in power transformers due to its low price and its good properties. However, the performances of this oil start to be limited with respect to the new requirements. Two ways are considered to solve this problem: find substitution liquids or improve the properties of mineral oil. We are interested by the second solution. Our work consists in mixing mineral oil with others types of insulating liquids for transformers, and finding the best o...

  9. Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161++TCR iVα7.2+ Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection

    Yean K. Yong

    2018-03-01

    Full Text Available Mucosal-associated invariant T (MAIT cells, defined as CD161++TCR iVα7.2+ T cells, play an important role in the innate defense against bacterial infections, and their functionality is impaired in chronic viral infections. Here, we investigated the frequency and functional role of MAIT cells in chronic hepatitis B virus (HBV infection. The peripheral CD3+CD161++TCR iVα7.2+ MAIT cells in chronic HBV-infected patients and healthy controls were phenotypically characterized based on CD57, PD-1, TIM-3, and CTLA-4, as well as HLA-DR and CD38 expression. The frequency of MAIT cells was significantly decreased among chronic HBV-infected individuals as compared to controls. Expression of CD57, PD-1, CTLA-4, as well as HLA-DR and CD38 on MAIT cells was significantly elevated in chronic HBV-infected individuals relative to controls. The percentage of T cell receptor (TCR iVα7.2+ CD161+ MAIT cells did not correlate with HBV viral load but inversely with HLA-DR on CD4+ T cells and MAIT cells and with CD57 on CD8+ T cells suggesting that decrease of MAIT cells may not be attributed to direct infection by HBV but driven by HBV-induced chronic immune activation. The percentage and expression levels of PD-1 as well as CTLA-4 on MAIT cells inversely correlated with plasma HBV-DNA levels, which may suggest either a role for MAIT cells in the control of HBV infection or the effect of HBV replication in the liver on MAIT cell phenotype. We report that decrease of TCR iVα7.2+ MAIT cells in the peripheral blood and their functions were seemingly impaired in chronic HBV-infected patients likely because of the increased expression of PD-1.

  10. Euroopa Inimõiguste Kohtu (suurkoja) otsus asjas Kononov vs. Läti (kaebus nr 36376/04) / Lauri Mälksoo ; inglise keelest tõlkinud Mait Laaring

    Mälksoo, Lauri, 1975-

    2011-01-01

    17. mail 2010 tegi Euroopa Inimõiguste Kohtu suurkoda otsuse asjas Kononov vs. Läti, otsustades, et Läti ei rikkunud Euroopa inimõiguste ja põhivabaduste kaitse konventsiooni artiklit 7, kui mõistis Vassili Kononovi süüdi Teise maailmasõja ajal Lätis toimepandud sõjakuriteos

  11. Omandi sundvõõrandamise instituut Eesti Vabariigi ja Saksamaa Liitvabariigi õiguskordades : (võrdlev käsitlus) : [bakalaureusetöö] / Mait Laaring ; Tartu Ülikool, õigusteaduskond ; juhendaja: Kalle Merusk

    Laaring, Mait, 1979-

    2003-01-01

    Sundvõõrandamise instituudi ajaloolisest arengust, mõistest, omandigarantii olemusest, sundvõõrandamisest ja sotsialiseerimisest (natsionaliseerimisest), sundvõõrandamise õiguspärasuse eeldustest, tagajärgedest, kohtulikust vaidlustamisest

  12. Reclame langs de weg en verkeersveiligheid : een notitie. In opdracht van het Verbond van Verzekeraars, Afdeling Motorrijtuigen.

    Hagenzieker, M.P.

    1996-01-01

    In this note a qualitative answer is given to the question whether placing advertising signs along motorways has an influence on traffic safety. It can be stated in general that especially the circumstances in which the driving task has to be performed are important for the possible effect of

  13. The New York Review of Books : (1998, 14. mai), nr. 8 : [ülevaade] / vahendanud Anne Lange

    1998-01-01

    Ka John Keatsi käsitlusest: Nicholase Roe' 'John Keats and the culture of dissent' ja Andrew Motioni 'Keats : a biography'; Nadine Gordimer romaanist 'The house of gun'; Franz Kafka 'Lossi' uustõlkest inglise keelde

  14. Tõlkimise kõrge kunsti kirjelduskeele otsingud jätkuvad: Tallinnas käis Douglas Robinson / Anne Lange

    Lange, Anne, 1962-

    2013-01-01

    Tõlketeadusest ja tõlketeadlasest Douglas Robinsonist. Sisaldab intervjuud Douglas Robinsoniga, kes pidas Tallinna Ülikooli kultuuriteaduste ja kunstide doktorikooli seminari raames avaliku loengu tõlkimisest

  15. Late Cretaceous Sub-Marine Fan System in Batain Mélange Zone, the Fayah Formation in Northeastern Oman

    Iftikhar Ahmed Abbasi

    2014-06-01

    Full Text Available The Batain coast along the northeastern margin of Oman between Ra’s Al-Hadd and Ra’s Jibsch, is comprised of Permian to Late Cretaceous complex stratigraphy in a tectonically deformed area recording Permian rifting to late Cretaceous Tethys closure events. These rocks are thrust over Mesozoic and older autochthonous sedimentary cover in the form of a major nappe structure known as the Batain Nappe. The uppermost part of the Batain nappe is comprised of isolated outcrops of early Maastrichtian siliciclastic Fayah Formation dominated by gravity flow deposits. The Fayah Formation in the Jabal Fayah area is over four hundred meters thick and comprised of five distinct facies associations; namely, i coarsening-up sandstone, ii conglomerate, iii debris- flow, iv turbidite, and v inter-bedded sandstone and shale lithofacies. These lithofacies associations are repeated many times in the section. The sandstone lithofacies association exhibits a coarsening-upward trend making sequences tens of meters thick in various parts of the formation. Waterscape structures are common along with occasional sandstone dykes and convolute bedding, reflecting fluidized conditions of deposition. The conglomerate lithofacies association is comprised of a series of interbedded coarsening-upward pebble to gravel size conglomerates containing chert, limestone, granite and volcanic clasts ranging a few mm to cm in diameter. Occasionally these are interbedded with sandstone lithofacies. The conglomerate lithofacies was deposited by a high-energy channelized flow in a sub-aqueous setting. The debris-flow lithofacies association is a matrix supported chaotic mixture of clay and boulders of granite, limestone and volcanic rocks, some of which are meter-sized in diameter, and possibly derived from the nearby basement rocks such as the Jabal Ja’alan basement rocks. It constitutes the most dominant part of the formation. These sediments were deposited along a slope setting, possibly as olistostrome formed due to submarine slumping and sliding. The turbidite lithofacies association is comprised of monotonous grayish-green to brown coloured clays tens of meters thick interbedded with thin, clean, well-sorted sandstone. The Interbedded sandstone and shale lithofacies association is comprised of a half to one meter thick cross-bedded, burrowed arkosic sandstone and plane laminated shale. The sandstone constitutes about 25% of the association with ripple lamination in the upper part of the unit indicating a fining-upward trend. Dewatering structures are common. This association constitutes the upper 100m of the formation. These sediments were deposited in shallow water conditions by channelized flows. Based on the lithofacies associations described above, especially the dominance of debris-flow units and turbidites, the greater part of the Fayah Formation are interpreted as having been deposited under a sub-marine fan setting. Only the upper part of the formation was deposited in a shallow water setting before the onset of overlying carbonate deposits. The sub-marine fan system was active during the last stages of the Tethys Ocean closure at the time of onset of the Batain nappe.

  16. L'utilisation d'un mélange de sels fondus pour le stockage de chaleur

    Roche , M.

    1980-01-01

    L'exploitation rationnelle de l'énergie solaire nécessite le stockage d'une partie de la chaleur produite aux heures d'ensoleillement pour pouvoir la restituer aux heures de consommation, ou tout au moins pour assurer la continuité du fonctionnement pendant les passages nuageux. Les sels fondus et en particulier le H.T.S. (Heat Transfer Salt) apparaissent comme les meilleurs fluides de stockage thermique. En effet, ils permettent un stockage d'une grande densité pour un faible coût et bénéfic...

  17. Anaesthesia management of a case of Jervell and Lange-Nielsen syndrome for minimally invasive bilateral thoracoscopic cervicothoracic sympathectomy

    Preety Mittal Roy

    2016-01-01

    Full Text Available Long QT syndrome (LQTS is an arrhythmogenic cardiac disorder resulting from the malfunction of cardiac ion channels. Patient with LQTS may present with syncope, seizures or sudden cardiac death secondary to polymorphic ventricular tachycardia (VT or torsades de pointes. Patient may be asymptomatic in the pre-operative period but may develop VT for the first time in operation theatre. We are reporting anaesthetic management of a child with LQTS planned for bilateral thoracoscopic cervicothoracic sympathectomy.

  18. 4.8 GHz Intra-Day Variability of FSRQ 0507+ 179 Lang Cui1,2 ...

    ture function (SF) analysis (except the second and fifth ones, which were roughly estimated visually according to the light curves, since there are very few data .... Abdo, A. A., Ackermann, M., Ajello, M., Allafort, A., Antolini, E., Atwood, W. B. et al. 2010,. ApJS, 188, 405. Bevington, P. R., Robinson, D. K. 1992, Data reduction ...

  19. Andmete kogumise ja süstematiseerimise kontekstuaalsed strateegiad / Joseph Hanson Kwabena Nketia ; tõlk. Anne Lange

    Kwabena Nketia, Joseph Hanson

    2005-01-01

    Aafrika muusikateadlase, etnomusikoloogi käsitlus kontekstist. Lühendatud tõlge artiklist "Contextual Strategies of Inquiry and Systematization" (Ethnomusicology, Journal of the Society for Ethnomusicology). Järgneb nr. 6, lk. 66-75

  20. Ring-wall enclosure of Lipa in Prehistoric Southern Harjumaa / Marge Konsa, Valter Lang, Karin Vimberg...[jt.

    2006-01-01

    Lipa vallsulendik kuulub Eestis väikesearvuliste muististe hulka, mille iseloomulikuks tunuseks on tasasele maale ehitatud kividest või mullast madal vall, mis ringikujuliselt piirab õueala. Leitud keraamika järgi võiks asulakiht kuuluda ajavahemikku eelrooma rauaaja lõpust kuni rooma rauaaja lõpuni

  1. Carbohydrate metabolism in Agaricus bisporus (Lange) Imbach: metabolism of [14C] labelled sugars by sporophores and mycelium

    Hammond, J.B.W.; Nichols, R.

    1977-01-01

    When growing sporophores and vegetative mycelium of Agaricus bisporus had been supplied with [ 14 C] labelled hexoses for varying periods of time, the major compounds labelled in both forms were mannitol, trehalose, glutamate, alanine and an unidentified substance. Mannitol was strongly labelled after application of [ 14 C] fructose but only weakly when [ 14 C] glucose was applied. The relative rates of oxidation by sporophores of labelled mannitol, trehalose, glucose and fructose were assessed by measuring 14 CO 2 production. Glucose and trehalose were the most rapidly oxidized substrates. Glucosephosphatase isomerase (E.C. 5.3.1.9) was extracted from sporohores and assayed. The conversion of glucose-6-phosphate to fructose-6-phosphate by the enzyme was competitively inhibited in vitro by 6-phosphogluconate. The control of mannitol synthesis and the functions of mannitol and trehalose are discussed. (author)

  2. Jordan and Lange: The California Junior College as Protector of Teaching. Working Papers in Education ED-94-1.

    Gallagher, Edward A.

    A group of contemporary historians has recently accused community and junior colleges of not offering the American masses new opportunities of upward social mobility, but instead of serving to divert them away from four-year colleges and universities. In particular, historians have taken issue with the efforts of David Jordan, of Stanford…

  3. THE MÉLANGE OF INNOVATION AND TRADITION IN MALTESE LAW: THE ESSENCE OF THE MALTESE MIX?

    B Andò

    2012-09-01

    Full Text Available Aim of this paper is to provide valuable insights into the Maltese legal system with a special focus on private law. The assumption is that this legal system is the by-product of the "mixing" of innovation and tradition, resulting from the interaction of English law and continental law. A major role in the development of the system is played by courts. Some examples (moral damages and pre-contractual liability are considered which highlight the importance of the function displayed by Maltese judges.

  4. Phlebotomine sand flies of edible-nest swiftlet cave of Lang Ga Jiew Island, Chumphon province, Thailand.

    Chittsamart, B; Samruayphol, Suchada; Sungvorayothin, Sangsit; Pothiwat, Ratcharin; Samung, Yudthana; Apiwathnasorn, Chamnarn

    2015-09-01

    The present study reported for the first time phlebotomine sandfly species inhabiting edible-nest swiftlet cave of the isolated island, based on field collections made during June 2010-May 2011. The insect diversity was relatively lower to that of mainland caves. All species, Phlebotomus stantoni, Sergentomyia anodontis, Sergentomyia bailyi, Sergentomyia gemmea, Sergentomyia hodgsoni and Sergentomyia punjabensis were either endemic island species or native elsewhere in Thailand. Sergentomyia hodgsoni was the most prevalent species accounted for 94.7% and classified as a troglophile species. Seasonal pattern of the phlebotomine abundance and some aspects of their population characteristics were described and discussed. Two ectoparasites, Ornithodorus and Paracimex sp. were also incidentally collected from the swiftlet cave.

  5. A novel RAD21 variant associated with intrafamilial phenotypic variation in Cornelia de Lange syndrome - review of the literature

    Boyle, M I; Jespersgaard, C; Nazaryan-Petersen, Lusine

    2017-01-01

    In a patient with CdLS (IV.16) we identifed a novel single basepair deletion (c.704delG) in RAD21, which encodes a cohesin pathway protein. The variant is predicted to result in a premature stop codon [p.(Ser235Ilefs*19)] and hereby would have a deleterious effect. RAD21 variants have previously ...

  6. Spectroscopie de diffusion de la lumière dans les mélanges de gaz atomiques

    Dixneuf , Sophie

    2006-01-01

    This thesis is a contribution to the study of the interaction-induced polarizabilities by rare gases, in both the coordinate and the frequency representation. For the first time, collision-induced Raman spectra by atomic gaseous mixtures were recorded, computed quantum mechanically, and interpreted. More specifically, anisotropic and isotropic Stokes spectral wings by room-temperature Ne-Ar were investigated up to 300 cm-1 , whereas the anisotropic wing of the Kr-Xe was explored up to 135 cm-...

  7. The calculation interest for administration of hydropower in the long-term; Kalkulasjonsrenta for vannkraftforvaltning paa lang sikt

    NONE

    2005-07-01

    A review of important findings in newer, economic literature on discount rate in the long term is presented. Based on this review, two questions relating to the administration of Norwegian hydropower resources are briefly discussed. Firstly, which discount rate should be used as basis when valuating the existent Norwegian hydropower plants? Secondly, how should the socio-economic discount rate for investments in hydro projects be determined compared relatively to other types of investments in the power sector? The main conclusion is that the existing rate for administration of hydropower need not be substituted. Neither theory nor empiricism provides a conclusive answer. Certain relevant aspects that may be further investigated are put forth (ml)

  8. Lufthastighed langs gulvet i et lokale med vægmonteret armatur og fortrængningsventilation

    Nielsen, Peter V.

    Luften fra vægmonterede lavimpulsarmaturer strømmer ved fortrængningsventilation direkte ind i opholdszonen. Det er derfor vigtigt at kunne bestemme den lufthastighed, der opstår i forskellig afstand fra armaturet for at fastlægge den termiske komfort i lokalet. I det følgende viser en række måli...

  9. Die invloed van herbivorie en vuur op die oorlewing van sekere meerjarige kruide langs die Sabierivier, Kruger Nasionale Park

    H. Myburgh

    2012-03-01

    Full Text Available Die groot vloede wat in die jaar 2000 in die Kruger Nasionale Park plaasgevind het, het dierivieroewerplantegroei versteur. Dit het die geleentheid gebied om heinings op te rig langsdie Sabierivier om herbivore uit sekere gebiede uit te sluit en sodoende die herstel van die rivieroewerekosisteme te monitor.

  10. Mõõdulindiga õnne ja edu kallal / Anneli Aasmäe

    Aasmäe, Anneli, 1973-

    2000-01-01

    Juhtimiskonsultant Mait Raava kinnitusel on edukus 70 protsenti kaasasündinud omadus, Eesti edukatel on tegutsemisvajadus veres, nad võivad toetuda Iisraeli päritolu juhtimisteoreetiku Eliyahu M. Goldratti õpetusele, mitte eduretsepte ja õnnevalemeid pakkuvaile autorite rivile Dale Carnegie'st Ben Furmanini. Kommentaarid: Aune Past, Mait Raava

  11. Märt Agu: "Isa vari käib mul kogu aeg kannul" / Märt Agu ; interv. Aigi Viira

    Agu, Märt

    2006-01-01

    1. okt. tähistas oma 30-aastast sünnipäeva ja oma ellukutsuja Mait Agu 55-sünniaastapäeva Tallinna Ülikooli koreograafiaosakond. Sel puhul esitati Estonias Mait Agu tantsulavastus "Kodalased ja kaasaegsed", mille seadis uuesti lavale Märt Agu oma isa loodud koreograafia põhjal

  12. 25 kaadrit sekundis / Liis Auväärt

    Auväärt, Liis

    2009-01-01

    Nukufilmis käib töö filmiga "Lisa Limone & Maroc Orange", režissöör Mait Laas, animaatorid Triin Sarapik-Kivi, Märt Kivi, operaator Ragnar Neljandi, nukumeistrid Heigo Eeriksoo, Taivo Müürsep, Ene Mellow ja Kreeta Käeri. Dekoratsioonimeistrid Mait Erik ja Roman Kuznetsov

  13. Reflections on 35 years with Applied Optics: outgoing editorial.

    Mait, Joseph N

    2014-10-20

    Applied Optics' Editor-in-Chief, Joseph N. Mait reflects on his experience as a reader, author, reviewer and eventual editor of the journal. Dr. Mait also introduces the incoming Editor-in-Chief, Ronald G. Driggers and acknowledges outgoing Division Editor, T.-C. Poon.

  14. Mucosal-Associated Invariant T Cells: New Insights into Antigen Recognition and Activation

    Xingxing Xiao

    2017-11-01

    Full Text Available Mucosal-associated invariant T (MAIT cells, a novel subpopulation of innate-like T cells that express an invariant T cell receptor (TCRα chain and a diverse TCRβ chain, can recognize a distinct set of small molecules, vitamin B metabolites, derived from some bacteria, fungi but not viruses, in the context of an evolutionarily conserved major histocompatibility complex-related molecule 1 (MR1. This implies that MAIT cells may play unique and important roles in host immunity. Although viral antigens are not recognized by this limited TCR repertoire, MAIT cells are known to be activated in a TCR-independent mechanism during some viral infections, such as hepatitis C virus and influenza virus. In this article, we will review recent works in MAIT cell antigen recognition, activation and the role MAIT cells may play in the process of bacterial and viral infections and pathogenesis of non-infectious diseases.

  15. Epigenetic silencing of V(DJ recombination is a major determinant for selective differentiation of mucosal-associated invariant t cells from induced pluripotent stem cells.

    Yutaka Saito

    Full Text Available Mucosal-associated invariant T cells (MAITs are innate-like T cells that play a pivotal role in the host defense against infectious diseases, and are also implicated in autoimmune diseases, metabolic diseases, and cancer. Recent studies have shown that induced pluripotent stem cells (iPSCs derived from MAITs selectively redifferentiate into MAITs without altering their antigen specificity. Such a selective differentiation is a prerequisite for the use of MAITs in cell therapy and/or regenerative medicine. However, the molecular mechanisms underlying this phenomenon remain unclear. Here, we performed methylome and transcriptome analyses of MAITs during the course of differentiation from iPSCs. Our multi-omics analyses revealed that recombination-activating genes (RAG1 and RAG2 and DNA nucleotidylexotransferase (DNTT were highly methylated with their expression being repressed throughout differentiation. Since these genes are essential for V(DJ recombination of the T cell receptor (TCR locus, this indicates that nascent MAITs are kept from further rearrangement that may alter their antigen specificity. Importantly, we found that the repression of RAGs was assured in two layers: one by the modulation of transcription factors for RAGs, and the other by DNA methylation at the RAG loci. Together, our study provides a possible explanation for the unaltered antigen specificity in the selective differentiation of MAITs from iPSCs.

  16. Développement d'un nouveau thermo-transformateur à absorption-démixtion : optimisation conjointe du cycle et du mélange de travail

    Noubli , Halima

    2010-01-01

    This work is a study of a new type of Absorption-Demixing Heat Transformer (ADHT), using a mixture exhibiting a miscibility gap at low temperature. In this cycle, the separation step is performed by settling obtained after cooling the mixture. The separation is then energetically free and enables to reach thermal yields higher than those obtained for classical absorption heat transformers where separation is done by distillation.In order to find suitable working mixtures to reach temperature ...

  17. Eesti luule ja poeetika tagasivaates : vestlus Vincent B. Leitchiga / Vincent B Leitch ; küsitles [ja tõlkis ning eessõna:] Anne Lange

    Leitch, Vincent B

    2002-01-01

    V. B. Leitch oli ilmumata jäänud koguteose "The poetry of Estonia: essays in comparative analysis" toimetaja. Kogumikus oleks ilmunud Yale'i ülikoolis peamiselt 1960. a-tel peetud ettekanded eesti luulest. Loengud korraldas Aleksis Rannit. V. B. Leitch meenutab ka Ants Orast, kes oli tema doktoritöö juhendaja Florida ülikoolis

  18. Evaluation of casing materials made from spent mushroom substrate and coconut fibre pith for use in production of Agaricus bisporus (Lange) Imbach

    Pardo-Gimenez, A.; Pardo-Gonzalez, J. E.

    2008-07-01

    The agronomic performance of different proportions of mixtures of coconut fibre (CF) pith and spent mushroom substrate (SMS) was studied for their use as casing material in mushroom cultivation. After chemical and biological characterisation of the casing substrates qualitative and quantitative production parameters were evaluated in a cycle of Agaricus production. An increase in the proportion of SMS reduced the number of carpophores and overall yield; while the first flush was delayed, mushroom size tended to increase and the mushrooms had a higher dry matter content and a better texture, although their colour was worse. Combinations of CF pith and SMS of 4:1 and 3:2 (v/v) gave biological efficiencies of 92.9 and 82.6 kg 100 kg-1 compost, respectively. These values compare well with that obtained from the commercial casings used as a control. The high electrical conductivity of the mixture containing the highest proportion of SMS would limit its use. However, the results indicate the viability of reusing SMS as an ingredient of casing material for mushroom cultivation. This alternative could be considered to partially replace the organic substrates normally used for mushroom cultivation, with the double advantage of decreasing cost and reducing the environmental impact of waste disposal. Additional key words: alternative casing, compost reuse, mushroom cultivation. (Author) 31 refs.

  19. Long tracks Energy: Views on ten years of research on green energy; Lange spor Energi: Blikk paa ti aar med forskning paa miljoevennlig energi

    Coldevin, Grete Haakonsen

    2011-07-01

    RENERGI is the The Research Council of Norway's strategic research program aimed the energy sector. The program has given and gives us central knowledge about technologies, solutions, policies and instruments that could help solve the energy and climate challenges and support the Norwegian business opportunities for value creation.The program period extending from 2004 to 2013. This booklet presents an analysis Research shows the development of the research program has funded from the beginning to the present. The analysis of RENERGI, we call it 'Long Track' follows selected projects and portfolios of projects through more year to track the effectiveness Research Council funding had. And what are the key findings? Experiences from RENERGI and from the precursors to the program, show that increased funding for research in this field triggers innovative research and innovation.The program means adapted to industry characteristics: Energy requires strong communities, and the program has helped to build up such over time. These strong communities nest ground for the establishment of Centres for environmentally friendly energy (FME), the newest addition by the Research Council of instruments in this area. Analysis of research over time are important because they show effect of investing public funds in research. When initiate research, there is great expectations to short-term results. We know it can take time before results come. What gives returns today often based on research many years. Research using these analyzes as part of our knowledge base for future priorities and in our dialogue with research funding ministries. Research teams can use the results to summarize own operations over time. Businesses can benefit greatly Long-term analysis showing that energy research has opened for business start-ups and established companies given new products they can create value from. 'Long Track' emphasizes the importance of thinking long-term: When a research starts up, it is not Obviously what effects it will produce. Often it can take a long time before the research yields results, and perhaps other areas than originally thought. This analysis shows several good examples of this. There are many more RENERGI projects than this analysis covers that have given important results. In sum, confirming our analysis and some broader portfolio analysis RENERGI has contributed significantly to develop solutions for future energy systems. This we take with us in the planning of further research after RENERGI expires.(Author)

  20. Évaluation in vitro et in vivo des perturbateurs endocriniens chez le poisson zèbre : cas de substances seules et en mélanges

    Serra , Hélène

    2017-01-01

    This PhD thesis aims at assessing the potential of innovative in vitro and in vivo zebrafish based bioassays for biomonitoring of surface water contamination by xeno-estrogens. For this purpose, the bioassays were applied to assess the effect of environmentally relevant surface water pollutants, alone and in simple (artificial) and complex (environmental samples) mixtures. The screening of surface water samples in zebrafish- (ZELH-zfERβ2 cells) and human-based (MELNcells) bioassays revealed q...

  1. Rotary balance data for a single-engine trainer design for an angle-of-attack range of 8 deg to 90 deg. [conducted in langely spin tunnel

    Pantason, P.; Dickens, W.

    1979-01-01

    Aerodynamic characteristics obtained in a rotational flow environment utilizing a rotary balance located in the Langley spin tunnel are presented in plotted form for a 1/6 scale, single engine trainer airplane model. The configurations tested included the basic airplane, various wing leading edge devices, elevator, aileron and rudder control settings as well as airplane components. Data are presented without analysis for an angle of attack range of 8 to 90 degrees and clockwise and counter-clockwise rotations.

  2. Let's Sing 'Auld Lang Syne' for the Upper Brandywine: Or, to continue with Burns, how the best laid environmental schemes of men "gang aft a-gley"

    Leopold, Luna Bergere

    1970-01-01

    Perhaps the most lamentable mistake that one can make is to be right too soon. This was the story of the Brandywine Plan, an attempt to organize local people for the permanent protection of the environmental amenities of their own land.The Upper East Branch of Brandywine Creek drains a rolling basin of farms, fields, woodlands, and a sprinkling of residential areas. Because it lies at the far edge of the commuting range to the population centers of Philadelphia and Wilmington, the basin's natural beauty has barely been touched by the blight of suburban sprawl. The waters of its streams are clear; its ample woodlands and fields are filled with wildlife. Driving slowly through the basin's winding roads and across its narrow bridges evokes the feeling of a pastoral painting, of the ideal landscape of rural eastern America.For two years, I had the privilege of working closely with a group preparing a land plan for the Brandywine area. The plan was designed to offer the inhabitants of the basin a feasible way to preserve forever the natural qualities of their region from the inevitable wave of urbanization. A report in Science magazine called it the perfect plan that failed.

  3. TBT-gehalten en effecten bij de Gewone Alikruik, de Gevlochten Fuikhoorn en de Purperslak langs de Nederlandse kust in 2014

    Hoek-van Nieuwenhuizen, van M.; Jol, J.G.; Kaag, N.H.B.M.

    2014-01-01

    Het doel van dit onderzoek is effecten van verontreiniging met organotinverbindingen, specifiek tributyltinverbindingen (TBT), vast te stellen. Gewone Alikruiken zijn algengrazers en in vergelijking met andere gastropoden vrij ongevoelig voor TBT.

  4. Neue Ausgrabungen in der Bronzezeitsiedlung von Asva - vorläufiger Untersuchungsstand und weitere Ergebnisse / Uwe Sperling, Valter Lang, Kristiina Paavel, Andres Kimber

    2015-01-01

    2012 - 2014 toimunud välitööde eesmärgiks oli teave asula sisemisest struktuurist. Uuringud näitavad mõnevõrra uut pilti metallitöö korraldusest. Asula olemuse mõistmisest on vajalik uurimistööde jätkamine

  5. Wind turbines along highways and on the dikes Houtribdijk and Afsluitdijk in the Netherlands. Windmolens langs autosnelwegen en op de waterkeringen Houtribdijk en Afsluitdijk

    Johanson, J C.P.; Meesters, H J.N.

    1993-10-29

    Attention is paid to the safety, control and maintenance of dikes with regard to the placing of wind turbines on the dikes, as mentioned in the title. Also the possible damage to the bird population and the visual impact of wind turbines are dealt with. 5 refs.

  6. Obstakels in wegbermen : een overzicht en beschrijving van in de literatuur beschreven onderzoek omtrent het gedrag bij botsingen vaste voorwerpen die voorkomen in zones langs de rijbaan.

    Schoon, C.C.

    1973-01-01

    If the idea of an obstacle is broadly interpreted every object which is in the way of a vehicle can be regarded as an obstacle. According to this definition all road users are also obstacles. In this literature study only exclusive fixed objects along the highway, such as lighting poles and columns

  7. « Le brassage des choses » : Autobiographie et mélange des genres dans Le Labyrinthe du Monde de Marguerite Yourcenar

    Woerkum, C.C.M. van

    2007-01-01

    In writing her autobiographic trilogy "Le Labyrinthe du Monde" the French author Marguerite Yourcenar (1903-1987) constantly postpone writing about her own life. In stead of autobiography, she uses other genres such as family chronics, biography, essay or novel. Yourcenar refuses to reveal essential

  8. Ecologie et croissance de Abies alba Mill. en peuplements purs et mélangés dans le Massif Vosgien (Nord-est de la France)

    Pinto , Paulina

    2006-01-01

    The objective of this work was to determine the ecological niche and growth of silver fir (Abies alba Mill.) in the Vosges Mountains (north-east France), in relation to environmental conditions and inter-specific competition. The data set used to study the ecological niche consisted in 325 phytoecological relevés extracted from the EcoPlant database. To study the growth of silver fir, 143 plots were carried out in this work using a stratified sampling design according to stand composition, el...

  9. Eesti lülitumine modernsusesse : "Noor-Eesti" roll poliitilise ja sotsiaalse mõtte mitmekesistamisel / Toivo Raun ; tõlkinud Anne Lange

    Raun, Toivo, 1943-

    2009-01-01

    Eestis juhatas modernse poliitika sisse 1905. a. revolutsioon. Revolutsiooniga ühel aastal ilmus "Noor-Eesti" esimene album. Rühmituse juhtivate teoreetikute seisukohti rahvusküsimuse, välispoliitika jt. küsimustes

  10. ”Den lange rejse …” – metaforiske betydningslag i filmmediet En analyse af Aarhus Universitets vejlednings-, branding- og rekrutteringskampagne 2012

    Christine Petersen

    2014-11-01

    Full Text Available Artiklen tager udgangspunkt i kampagnefilmen ”Tænk. Hvis det er dig”, som var en del af den branding-, vejlednings- og rekrutteringskampagne, som Aarhus Universitet lancerede i 2012, og på baggrund af en analyse af filmens komposition samt billed- og lydside undersøger artiklen, hvordan kampagnefilmen opbygger en handlingsmæssig struktur, som realiserer en grundlæggende metaforisk forståelse af ’uddannelse som en rejse’. Ved hjælp af George Lakoff og Mark Johnsons metaforteori undersøges den anvendte metafors beskaffenhed, struktur og betydning(er, og i artiklen argumenterer vi for en tolkning af den anvendte metafor som ’uddannelse som en moderne dannelsesrejse’. Lakoff og Johnsons metaforteori, som tager udgangspunkt i sproglige tegn, vil i denne artikel blive anvendt på analysen af visuelle tegn, og dermed ønsker vi at demonstrere, at et oprindeligt sproglig-tekstuelt baseret metaforbegreb også kan bidrage til en bedre forst.else af visuel-fi lmiske narrative teknikker.

  11. lange versus forearc contributions to sedimentation and uplift, during rapid denudation of a young Banda forearc-continent collisional belt

    Duffy, Brendan; Kalansky, Julie; Bassett, Kari; Harris, Ron; Quigley, Mark; van Hinsbergen, Douwe J J; Strachan, Lorna J.; Rosenthal, Yair

    2017-01-01

    New sedimentary geochemistry and petrographic analyses provide the most extensive sedimentary documentation yet of the rapid denudation of the young Timor orogen. The data from three basins including two widely-separated, well-dated sections of the Synorogenic Megasequence of Timor-Leste, and a

  12. Pancreas Protective Effect of Button Mushroom Agaricus bisporus (JE Lange) Imbach (Agaricomycetidae) Extract on Rats with Streptozotocin-Induced Dia betes

    Yamac, M.; Kanbak, G.; Zeytinoglu, M.; Senturk, H.; Bayramoglu, G.; Dokumacioglu, A.; Griensven, van L.J.L.D.

    2010-01-01

    In the present study we describe the effects of hot water extract of the culinary-medicinal button mushroom, Agaricus bisporus, on the symptoms of streptozotocin-induced diabetes in Sprague Dawley rats. A. bisporus extract at the doses of 0, 100, 200, and 400 mg/kg body weight (bw) per day were

  13. Long tracks Energy: Views on ten years of research on green energy; Lange spor Energi: Blikk paa ti aar med forskning paa miljoevennlig energi

    Coldevin, Grete Haakonsen

    2011-07-01

    RENERGI is the The Research Council of Norway's strategic research program aimed the energy sector. The program has given and gives us central knowledge about technologies, solutions, policies and instruments that could help solve the energy and climate challenges and support the Norwegian business opportunities for value creation.The program period extending from 2004 to 2013. This booklet presents an analysis Research shows the development of the research program has funded from the beginning to the present. The analysis of RENERGI, we call it 'Long Track' follows selected projects and portfolios of projects through more year to track the effectiveness Research Council funding had. And what are the key findings? Experiences from RENERGI and from the precursors to the program, show that increased funding for research in this field triggers innovative research and innovation.The program means adapted to industry characteristics: Energy requires strong communities, and the program has helped to build up such over time. These strong communities nest ground for the establishment of Centres for environmentally friendly energy (FME), the newest addition by the Research Council of instruments in this area. Analysis of research over time are important because they show effect of investing public funds in research. When initiate research, there is great expectations to short-term results. We know it can take time before results come. What gives returns today often based on research many years. Research using these analyzes as part of our knowledge base for future priorities and in our dialogue with research funding ministries. Research teams can use the results to summarize own operations over time. Businesses can benefit greatly Long-term analysis showing that energy research has opened for business start-ups and established companies given new products they can create value from. 'Long Track' emphasizes the importance of thinking long-term: When a research starts up, it is not Obviously what effects it will produce. Often it can take a long time before the research yields results, and perhaps other areas than originally thought. This analysis shows several good examples of this. There are many more RENERGI projects than this analysis covers that have given important results. In sum, confirming our analysis and some broader portfolio analysis RENERGI has contributed significantly to develop solutions for future energy systems. This we take with us in the planning of further research after RENERGI expires.(Author)

  14. Etude de la cristallisation d’une nouvelle molécule à efficacité cardiotonique dans un mélange liquide ionique - eau

    Resende de Azevedo , Jacqueline

    2014-01-01

    The anti-solvent crystallization allows obtaining micro/nanoparticles, but it presents some disadvantages. In the case of new pharmaceutical molecules, as the LASSBio-294, the solubility in water or organic solvents is very low limiting the application of this operation. The use of Ionic Liquids (ILs) as alternative solvents opens new perspectives in pharmaceutical processing through anti-solvent crystallization process. Unlike conventional solvents, ILs are entirely composed of ions. ILs are...

  15. Udbredelsen af den invasive børsteorm, Marenzelleria viridis, langs danske kyster – tegn på økologiske konsekvenser?

    Banta, Gary Thomas; Christoffersen, Kenn

    ud af de 6 resterende stationer vi undersøgte. Antallet af M. viridis på disse stationer var dog beskeden (... tæthed af M. viridis og en række sediment og abiotiske parametre, hvilket bekræfter artens store tolerance overfor det omskiftelige brakvands miljø og sediment karakteristika, der kendetegner de danske kyster. Disse abiotiske parametre understøtter dog forekomsten af lige netop M. viridis frem for de...... andre søskendearter, da sidstnævnte fortrækker enten lavere salinitet eller lavere temperatur end typisk for de danske kyster. Der blev observerede nogle svage negative sammenhæng mellem Marenzelleria viridis og de naturligt forekommende arter, såsom Hediste (Nereis) diversicolor, Corophium spp. og...

  16. Deletion of 11q12.3-11q13.1 in a patient with intellectual disability and childhood facial features resembling Cornelia de Lange syndrome

    Boyle, Martine Isabel; Jespersgaard, Cathrine; Nazaryan, Lusine

    2015-01-01

    Deletions within 11q12.3-11q13.1 are very rare and to date only two cases have been described in the literature. In this study we describe a 23-year-old male patient with intellectual disability, behavioral problems, dysmorphic features, dysphagia, gastroesophageal reflux and skeletal abnormalities...

  17. Elena de Miguel, Azucena Palacios y Ana Serradilla (eds.) Estructuras Léxicas y Estructura del Léxico, Peter Lang, 2006. 367 p

    Vinther, Thora

    2008-01-01

    Anmeldelse af en samling artikler der inddrager studiet af ord og ordsammensætninger med mange forskellige tilgange, herunder semantiske og kognitive principper, kontrastivt eller diakront udgangspunkt....

  18. Effet du mélange du fluazifop et du bentazon sur les adventices et quelques cultures légumineuses

    Ngouajio, M.

    1993-01-01

    Full Text Available Effect of fluazifop and bentazon tank-mixed on weeds and selected legume crops. Field trials were conducted in Dschang, Cameroon, during the dry season (1991 and the rainy season (1992 to evaluate weed control and crop susceptibility to fluazifop-P (250 g ai/ha and fluazifop-P (250 g ai/ha plus bentazon (750 g ai/ha. Different legume crops included : peanuts, soybeans, cowpea, and common beans varieties white, red, maringue, multicolor and earth-color. Plots treated with fluazifop resulted in 91 and 98 % control of Setaria barbata and Cynodon dactylon, respectively. When tank-mixed with bentazon, fluazifop activity dropped to 38 and 88 % for the control of S. barbata and C. dactylon, respectively. Broadleaf weeds (Mimosa pudica and Ageratum conyzoides were more effectively controlled with the mixture of both herbicides. Significant crop injury (22-67 % was observed during the dry season trial on all varieties with the herbicides combination. This resulted in significant stand reduction with the most susceptible crop being cowpea (52 % stand reduction. Yield reduction was observed when cowpea was treated with fluazifop plus bentazon (47 kg/ha compared to 145 kg/ha for fluazifop usedalone or 138.5 kg/ha for the control.

  19. Barbara Zibell (Hg.: Gender Building. Sozialräumliche Qualitäten im öffentlichen Hochbau. Frankfurt am Main u.a.: Peter Lang Verlag 2009.

    Kerstin Dörhöfer

    2009-11-01

    Full Text Available Nachdem die Mitgliedstaaten der Europäischen Union begonnen hatten, die Vorgaben des Amsterdamer Vertrags von 1999 zur Förderung der Gleichstellung von Mann und Frau durch Gender Mainstreaming umzusetzen, sahen sich auch die öffentlichen Bauverwaltungen veranlasst, ihre Planungs- und Bauprojekte diesem Verfahren zu unterziehen. Beispiele verschiedener Sektoralbereiche des öffentlichen Hochbaus in vier europäischen Ländern werden in diesem Sammelband dokumentiert und die Verfahren des Gender Mainstreaming in der Praxis von Architektur und Städtebau vorgestellt. Ergebnis sind Kriterienkataloge und Anregungen für weitere Vorhaben. Der Band bietet einen erhellenden Einblick in das bisherige Prozedere dieser Top-down-Strategie bei Bauten der Öffentlichkeit.After the member states of the European Union began to use gender mainstreaming to implement the guidelines of the 1999 Amsterdam Treaty, which demands the equality of man and woman, public building authorities were prompted to subject their planning and building projects to this policy. This collected volume documents and presents examples from various sectors of public engineering in four European countries and the methods of gender mainstreaming in the practice of architecture planning and city building. The result is a catalogue of criteria and suggestions for future projects. The volume offers an illuminating view into current procedures for this top-down strategy for public construction.

  20. De verlichting van tunnelingangen : een probleemanalyse omtrent de verlichting overdag van lange tunnels. Deel I: Studie van de literatuur. Deel II: Tabellen, figuren, annexen, bibliografie.

    Schreuder, D.A.

    1981-01-01

    During long time the recommendations set up by the CIE have been the starting point for the design of lighting installations in traffic tunnels. Due to the changing insight in the different aspects of tunnel lighting the recommendations are reconsidered and in particular those for tunnel entrances.

  1. Accessory minerals and subduction zone metasomatism: a geochemical comparison of two mélanges (Washington and California, U.S.A.)

    Sorensen, Sorena S.; Grossman, Jeffrey N.

    1993-01-01

    The ability of a subducted slab or subducted sediment to contribute many incompatible trace elements to arc source regions may depend on the stabilities of accessory minerals within these rocks, which can only be studied indirectly. In contrast, the role of accessory minerals in lower-T and -P metasomatic processes within paleo-subduction zones can be studied directly in subduction-zone metamorphic terranes.

  2. Tõlkelised ebakõlad totalitarismi monoloogis : järjepidevused, katkestused ja varjatud konfliktid Nõukogude Eesti tõlkeloos / Anne Lange, Daniele Monticelli

    Lange, Anne, 1962-

    2013-01-01

    Artikkel keskendub tõlkimisele nõukogude Eestis, pidades silmas kahte eesmärki: esiteks mõista tõlke olulist rolli Eesti kultuurilises ümberkujunemises Nõukogude liiduvabariigiks, teiseks mõtestada tõlketegevust nõukogude sotsiaalpoliitilistes ning kultuurilistes tingimustes

  3. Esilinastus väge täis "Mina olin siin" / Kutt Kommel

    Kommel, Kutt

    2008-01-01

    Rene Vilbre noortefilm "Mina olin siin", mille aluseks on Sass Henno romaan "Mina olin siin. Esimene arest" : operaator Mait Mäekivi : osades Rasmus Kaljujärv, Hele Kõre jt : Amrion Productions - Helsinki-filmi OY 2008

  4. "Mina olin siin", võib vastu hambaid saada / Andres Keil

    Keil, Andres, 1974-

    2007-01-01

    Noortefilmi "Mina olin siin" võtetel. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos

  5. Veider nelik jätkab!

    2008-01-01

    Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (lavastanud Tim McGrath ja Eric Darnell, eesti keeles loevad teksti Karol Kuntsel, Andero Ermel, Evelin Pang, Argo Aadli, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik, Anne Reemann jt)

  6. Juutide uurimine tõi tunnustuse : eesti teadlaste artikkel jõudis maailma tippajakirja / Marju Himma

    Himma, Marju

    2010-01-01

    Juutide erinevate kogukondade genotüübilistele erinevuste uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayev, Mait Metspalu ja Richard Villems. Artikkel ilmus teadusajakirjas Nature

  7. Vene Kultuurikeskus = The Russian Culture Centre / Margit Mutso

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Mere puiestee 5 asuva hoone (arhitekt A. Kuznetsov, 1954) restaureerimisest. Arhitekt Niina Mäger, sisearhitekt Anne Tamverk. Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

  8. Tallinna Loomeinkubaator = Creative Incubator in Tallinn / Margit Mutso

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Veerenni 24C asuva Tallinna Loomeinkubaatori sisekujundusest. Sisearhitektid Raul Tiitus, Tarmo Piirmets (Pink OÜ), graafiline kujundus: Kaarel Vahtramäe (Velvet Studio). Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud sisekujundusele

  9. Nukufilm lasi käiku pooletunnise 3D-seiklusfilmi / Tiit Tuumalu

    Tuumalu, Tiit, 1971-

    2009-01-01

    Stuudios Nukufilm algasid pooletunnise 3D-nukufilmi "Lisa Limone ja Maroc Orange'i tormakas armulugu" võtted. Filmi režissöör on Mait Laas, stsenaristid Kati Kovacs ja Peep Pedmanson, produtsent Arvo Nuut

  10. Endine turujuht end süüdi ei tunnistanud / Hannes Krause

    Krause, Hannes

    2005-01-01

    Vadim Polishtshuk, keda süüdistatakse koos kahe kaaslasega Mait Metsamaa mõrvaprotsessi peamise tunnistaja ähvardamise ja mõjutamise katses, ei tunnistanud end 19. septembril Tallinna linnakohtus alanud protsessil süüdi

  11. Mentorklubi süstib väikeettevõtjale tegutsemiskindlust / Teeli Remmelg

    Remmelg, Teeli

    2005-01-01

    Tallinna Mentorklubi tegevusest, kus väikeettevõtjad õpivad üksteise vigadest ja õnnestumistest. Kommenteerivad EASi mentorprogrammi koordinaator Liina Võrkaed ja Pro Konsultatsioonid, Tallinna Mentorklubi mentor Mait Raava

  12. Tri gorsti za Tsentralnõi rõnok / Arvi Tapver

    Tapver, Arvi

    1999-01-01

    Mõrvatud endise abilinnapea Mait Metsamaa keskturu erastajatest kaaskond kahlustas tunnistaja sõnul topeltmängu, kui Metsamaa vanale sõbrale ja allilmas kardetavale Meelis Laole erastamisest loobumise eest hüvitist pakkus

  13. Kaebus sunnib teatreid suitsetamise osas aru pidama

    2009-01-01

    Draamateatri külastaja kaebuse peale - etenduses "Pedro Páramo" suitsetas näitleja Mait Malmsten kogu esimese vaatuse - arutab Eesti Etendusasutuste Liit peagi laval suitsetamisega seotud küsimusi

  14. Vana kaader järel-eesti ajal võimalusi proovimas / Maie Kalda

    Kalda, Maie, 1929-2013

    2001-01-01

    Artikkel põhineb konverentsil "Kohandumise märgid" (20. apr. 2001) peetud ettekandel. Kirjanike elu- ja loominguloost a-tel 1944-1948, lähemalt Mait Metsanurgast, Hugo Raudsepast, Friedebert Tuglasest ja Oskar Lutsust

  15. Ilmafilosoofia ilma filosoofiata / Jüri Rato

    Rato, Jüri

    2000-01-01

    Arvustus: Hoff, Benjamin. Puhh ja Tao / tlk. Mait Talts. Tln. : Olympia, 1998 ; Hoff, Benjamin. Notsu ja Te / tlk. Paavo Kivine. Tln.: Olympia, 1999 ; Allen, Roger E. ; Allen, Stephen D. Puhh lahendab probleeme / tlk. Paavo Kivine. Tallinn : Olympia, 2000

  16. Akna varastamine : eesti Y-kirjandus / Berk Vaher

    Vaher, Berk, 1975-

    2014-01-01

    Valdur Mikita, Erkki Luuk'i, Kiwa, Kaspari ja kirjanike rühmituse “14 NÜ” (Mait Laas, Paavo Matsin, Marko Mägi, Erkki Kadarik, Marianne Ravi, Maarja Vaino, Trip Jarvis, Johannes Üksi) loomingust

  17. Inimesed ja mesilased / Rein Tootmaa

    Tootmaa, Rein

    2005-01-01

    Nukufilm "Gene+ratio" : stsenarist, kunstnik ja režissöör Mait Laas : konsultant Paavo Matsin : operaatorid Ragnar Neljandi, Raivo Möllits : helilooja Tiit Kikas : Nukufilm OÜ - Icon Film (Saksamaa) 2005

  18. Eesti animafilmid võitsid Raumas

    pPIK mare 2010

    1999-01-01

    VI Sinise Mere filmifestivalil Raumas jagasid A-sarjas esikohta Mait Laasi "Päevavalgus" ja Peep Pedmansoni "Just Märried", teiseks jäi Märt Sildvee "Guardian Angel" ja kolmandaks Riho Undi - Hardi Volmeri "Primavera"

  19. Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells

    Salerno-Goncalves, Ros?ngela; Luo, David; Fresnay, Stephanie; Magder, Laurence; Darton, Thomas C.; Jones, Claire; Waddington, Claire S.; Blohmke, Christoph J.; Angus, Brian; Levine, Myron M.; Pollard, Andrew J.; Sztein, Marcelo B.

    2017-01-01

    Gastrointestinal infections by Salmonella enterica serovar Typhi (S. Typhi) are rare in industrialized countries. However, they remain a major public health problem in the developing world with an estimated 26.9 million new cases annually and significant mortality when untreated. Recently, we provided the first direct evidence that CD8(+) MAIT cells are activated and have the potential to kill cells exposed to S. Typhi, and that these responses are dependent on bacterial load. However, MAIT c...

  20. Mucosal-Associated Invariant T Cell Interactions with Commensal and Pathogenic Bacteria: Potential Role in Antimicrobial Immunity in the Child

    Liana Ghazarian

    2017-12-01

    Full Text Available Mucosal-associated invariant T (MAIT cells are unconventional CD3+CD161high T lymphocytes that recognize vitamin B2 (riboflavin biosynthesis precursor derivatives presented by the MHC-I related protein, MR1. In humans, their T cell receptor is composed of a Vα7.2-Jα33/20/12 chain, combined with a restricted set of Vβ chains. MAIT cells are very abundant in the liver (up to 40% of resident T cells and in mucosal tissues, such as the lung and gut. In adult peripheral blood, they represent up to 10% of circulating T cells, whereas they are very few in cord blood. This large number of MAIT cells in the adult likely results from their gradual expansion with age following repeated encounters with riboflavin-producing microbes. Upon recognition of MR1 ligands, MAIT cells have the capacity to rapidly eliminate bacterially infected cells through the production of inflammatory cytokines (IFNγ, TNFα, and IL-17 and cytotoxic effector molecules (perforin and granzyme B. Thus, MAIT cells may play a crucial role in antimicrobial defense, in particular at mucosal sites. In addition, MAIT cells have been implicated in diseases of non-microbial etiology, including autoimmunity and other inflammatory diseases. Although their participation in various clinical settings has received increased attention in adults, data in children are scarce. Due to their innate-like characteristics, MAIT cells might be particularly important to control microbial infections in the young age, when long-term protective adaptive immunity is not fully developed. Herein, we review the data showing how MAIT cells may control microbial infections and how they discriminate pathogens from commensals, with a focus on models relevant for childhood infections.

  1. Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?

    Haeryfar, S M Mansour; Shaler, Christopher R; Rudak, Patrick T

    2018-02-22

    Mucosa-associated invariant T (MAIT) cells are a subset of innate-like T lymphocytes known for their ability to respond to MHC-related protein 1 (MR1)-restricted stimuli and select cytokine signals. They are abundant in humans and especially enriched in mucosal layers, common sites of neoplastic transformation. MAIT cells have been found within primary and metastatic tumors. However, whether they promote malignancy or contribute to anticancer immunity is unclear. On the one hand, MAIT cells produce IL-17A in certain locations and under certain circumstances, which could in turn facilitate neoangiogenesis, intratumoral accumulation of immunosuppressive cell populations, and cancer progression. On the other hand, they can express a potent arsenal of cytotoxic effector molecules, NKG2D and IFN-γ, all of which have established roles in cancer immune surveillance. In this review, we highlight MAIT cells' characteristics as they might pertain to cancer initiation, progression, or control. We discuss recent findings, including our own, that link MAIT cells to cancer, with a focus on colorectal carcinoma, as well as some of the outstanding questions in this active area of research. Finally, we provide a hypothetical picture in which MAIT cells constitute attractive targets in cancer immunotherapy.

  2. Intra-Hepatic Depletion of Mucosal-Associated Invariant T Cells in Hepatitis C Virus-Induced Liver Inflammation.

    Bolte, Fabian J; O'Keefe, Ashley C; Webb, Lauren M; Serti, Elisavet; Rivera, Elenita; Liang, T Jake; Ghany, Marc; Rehermann, Barbara

    2017-11-01

    Chronic hepatitis affects phenotypes of innate and adaptive immune cells. Mucosal-associated invariant T (MAIT) cells are enriched in the liver as compared with the blood, respond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated from the gut. Little is known about the role of MAIT cells in livers of patients with chronic hepatitis C virus (HCV) infection and their fate after antiviral therapy. We collected blood samples from 42 patients with chronic HCV infection who achieved a sustained virologic response after 12 weeks of treatment with sofosbuvir and velpatasvir. Mononuclear cells were isolated from blood before treatment, at weeks 4 and 12 during treatment, and 24 weeks after the end of treatment. Liver biopsies were collected from 37 of the patients prior to and at week 4 of treatment. Mononuclear cells from 56 blood donors and 10 livers that were not suitable for transplantation were used as controls. Liver samples were assessed histologically for inflammation and fibrosis. Mononuclear cells from liver and blood were studied by flow cytometry and analyzed for responses to cytokine and bacterial stimulation. The frequency of MAIT cells among T cells was significantly lower in blood and liver samples of patients with HCV infection than of controls (median, 1.31% vs 2.32% for blood samples, P = .0048; and median, 4.34% vs 13.40% for liver samples, P = .001). There was an inverse correlation between the frequency of MAIT cells in the liver and histologically determined levels of liver inflammation (r = -.5437, P = .0006) and fibrosis (r = -.5829, P = .0002). MAIT cells from the liver had higher levels of activation and cytotoxicity than MAIT cells from blood (P liver inflammation and MAIT cell activation and cytotoxicity, and increased the MAIT cell frequency among intra-hepatic but not blood T cells. The MAIT cell response to T-cell receptor-mediated stimulation did not change during the 12 weeks of

  3. Kinetics of fibrilar aggregation of food proteins

    Arnaudov, L.N.

    2005-01-01

    In this thesis we study the kinetics of fibrilar aggregation of two model proteins widely used in the food industry -lang=EN-GB style='font-family:Symbol'>blang=EN-GB>-lactoglobulin (lang=EN-GB style='font-family:Symbol'>blang=EN-GB>-lg) and hen

  4. "Having fun with the long take"

    Nielsen, Jakob Isak

    2007-01-01

    Den lange uklippede indstilling rummer mange forskelligartede iscenesættelsesstrategier. Denne artikel føjer et ekstra kapitel til den efterhånden lange historie om den lange indstilling ved at undersøge en anvendelse, som er underbelyst i litteraturen: den lange indstilling som komisk henvendels...

  5. Les formations de la marge néotethysienne et les mélanges ophiolitiques de la zone de suture de l'Indus en Himalaya du Ladakh - Inde. - Stratigraphie, tectonique, évolution géodynamique

    Sutre , Eric

    1990-01-01

    Dans la zone de suture de l'Indus en l'Himalaya du Ladakh, l'étude lithostratigraphique, biostratigraphique, sédimentologique, pétrographique et structurale, conduit à différencier plusieurs catégories d'unités: - les unités appartenant à la marge nord néotéthysienne ; - des témoins de l'espace océanique néotéthysien ; - des unités de marge distale sud néotéthysienne (nord-indienne), Ces données, associées à une interprétation en terme de stratigraphie séquentielle, permettent de préciser la ...

  6. Su, X. (2011. Reflexivität im Chinesischen: Eine integrative Analyse: Mit zwei Anhängen von Hans-Heinrich Lieb. (XIV + 293 pp.. Frankfurt am Main: Peter Lang. Paperback.

    Mateja PETROVČIČ

    2011-10-01

    Full Text Available This book was published in the Linguistics Series of European University Studies, and is written in German. As the book's title suggests, this monograph is primarily a comprehensive analysis of reflexivity in spoken Standard Chinese in the framework of Integrational Linguistics. The author demonstrates that Chinese marks reflexivity only phonologically, with the use of reflexive pronoun(s, and argues that ziji (自己 is the only reflexive pronoun in Standard Chinese. Different languages distinguish between referential and non-referential reflexive pronouns, and the author briefly demonstrates this with German sich. Referential uses denote semantic reflexivity (inhaltliche Reflexivität, whereas non-referential uses represent formal reflexivity (formale Reflexivität. Su asserts that the Chinese reflexive pronoun ziji is always referential and that there is no formal reflexivity in Chinese. Since the research mainly focuses on the word ziji, not only in its reflexive usage but also in relation to intensifying and contrastive meanings and effects, this monograph could also be considered as a comprehensive research on ziji in Standard Chinese.

  7. Étude des antineutrinos de réacteurs : mesure de l'angle de mélange leptonique θ₁₃ et recherche d'éventuels neutrinos stériles

    Collin, Antoine

    2014-01-01

    The Double Chooz experiment aims to measure the θ₁₃ mixing angle through the disappearance—induced by the oscillation phenomenon—of anti-neutrinos produced by the Chooz nuclear reactors. In order to reduce systematic uncertainties, the experiment relies on the relative comparison of detected signals in two identical liquid scintillator detectors. The near one, giving the normalization of the emitted flux, is currently being built and will be delivered in spring 2014. The far detector, sensiti...

  8. The possible hindrance of a 8 MW wind farm along the Zuidermeerdijk in the Noordoostpolder, Netherlands, for birds. De mogelijke hinder van een 8 MW windpark langs de Zuidermeerdijk (NOP) voor vogels

    Van den Bergh, L M.J.; Spaans, A L

    1993-01-01

    The title farm comprises 16 three-bladed 500 kW wind turbines. Hindrance of wind turbines are collisions with the wind turbines and in the wake behind the blades and loss or disintegration of the natural habitat because of the presence of the wind turbines (aspect of disturbance). The title study is focused on counting the number of collision bird victims per year, and analyzing the disturbance effects on hibernating and foraging birds. It appeared that almost 150 to more than 1500 birds will collide with one of the 16 wind turbines. A few hundred tufted ducks, some tens of pochard and some tens of wild ducks per kilometre of the wind farm will leave their natural habitat. Based on the results it is concluded that the dike area between kilometre marker 32.5 and kilometre marker 35.5 is the most suitable area for a wind turbine array along the Zuidermeerdijk in between Schokkerhaven and Ketelbrug, both Netherlands. 3 figs., 5 tabs., 2 appendices, 33 refs.

  9. The possible hindrance of a 10 MW wind farm along the Noordermeerdijk in the Noordoostpolder, Netherlands, for birds. De mogelijke hinder van een 10 MW windpark langs de Noordermeerdijk (NOP) voor vogels

    Van den Bergh, L M.J.; Spaans, A L

    1993-01-01

    The title farm comprises 14 two-bladed 750 kW wind turbines. Hindrance of wind turbines are collisions with the wind turbines and in the wake behind the blades and loss or disintegration of the natural habitat because of the presence of the wind turbines (aspect of disturbance). The title study is focused on counting the number of collision bird victims per year, and analyzing the disturbance effects on hibernating and foraging birds. It appeared that almost 150 to more than 1500 birds will collide with one of the 16 wind turbines. A few hundred tufted ducks, some tens of pochard and some tens of wild ducks per kilometer of the array will leave their natural habitat. Based on the results it is concluded that the site south of the kilometre marker 7.0 is preferred to the site directly south of kilometre marker 5.0. It is also concluded that the above-mentioned array is preferred to a wind turbine array of 16 wind turbines of 500 kW each. The results of the investigation on that array are published in a separate report for which a separate abstract has been prepared. 2 figs., 6 tabs., 2 appendices, 34 refs.

  10. Art. 59 Abs. 2 S. 1 GG im Lichte von Brexit und IStGH-Austritt. Zur Parlamentarisierung der Kündigung völkerrechtlicher Verträge / Felix Lange

    Lange, Felix

    2017-01-01

    Rahvusvahelistest lepingutest loobumisest ja parlamendi kaasamisest otsustusprotsessi Saksa põhiseaduse artikli 59 tähenduses; Suurbritannia ja Lõuna-Aafrika ülemkohtute lahenditest. Kokkuvõte inglise keeles

  11. The state as a refugee. Pt. 2. The long way from DIN 4108 to EnEV; Der Staat als Getriebener. T. 2. Der lange Weg von der DIN 4108 bis zur EnEV

    Eicke-Hennig, Werner [Institut Wohnen und Umwelt, Darmstadt (Germany)

    2011-01-15

    The 1980ies and 1990ies were the time of fruitful energy discussions. Low-energy buildings and passive houses were defined. Clear standards of consumption were set and heat balance programs were developed. This was performed outside of Federal Ministries and universities. This was conceived by pioneers and small institutions, promoted by some Federal States, motivated and supported by an increasing environmental movement. In the 1990ies, everything pushed to an introduction of the low energy standard. However, the WSVO novella 1995 (WVO - Ordinance on Heat Insulation of Buildings) and the introduction of the Energy Saving Ordinance in 2002 (EnEV 2002) missed this target considerably.

  12. ‘The Vienna school and Central European art history’: Jan Bakoš, Discourses and strategies: the role of the Vienna School in shaping central European approaches to art history ‡ related discourses, Frankfurt am Main: Peter Lang, 2013

    Branko Mitrović

    2014-12-01

    Full Text Available Jan Bakoš’s recent book Discourses and strategies: the role of the Vienna School in shaping central European approaches to art history ‡ related discourses presents a comprehensive picture of the Vienna School of art history from its inception in the mid-nineteenth century to the influence it exercised on Central European scholarship in the second half of the twentieth century. Although the book is a collection of essays that have been published or presented in the past it is very coherent in the perspective it provides. A particularly important merit of the book is the presentation of the works of Slavic- and Hungarian-speaking art historians that are often ignored in contemporary English-speaking scholarship.

  13. Advies over de praktijkproef met lange en zware voertuigen : de verkeersveiligheidsconsequenties nader beschouwd van vrachtautocombinaties tot 25,25 meter. In opdracht van het Ministerie van Verkeer en Waterstaat, Adviesdienst Verkeer en Vervoer AVV.

    Schoon, C.C.

    1999-01-01

    In this study, the road safety aspects of a practical test for long and heavy lorries were investigated. The 'Long and Heavier Vehicles' (LHV's) Project Group preconditions were tested. Potential accident manoeuvres of long lorries were investigated using the most frequent accident manoeuvres. A

  14. Mixing and CP violation in the B$0\\atop{s}$ meson system at CDF; Mélange et violation de CP dans le système des mésons B$0\\atop{s}$ à CDF

    Di Giovanni, Gian Piero [Univ. of Paris VI-VII (France)

    2008-01-01

    The two analyses presented in the thesis, the B$0\\atop{s}$ mixing analysis and the B$0\\atop{s}$ → J/ψφ angular analysis, share most of the technical implementations and features. Thus, my choice was to pursue in parallel the common aspects of the analyses, avoiding, whenever possible, repetitions. Each Chapter is split in two parts, the first one dedicated to the B$0\\atop{s}$ mixing analysis and the second one describing the angular analysis on the B$0\\atop{s}$ → J/ψφ decay mode. They are organized as follows. In Chapter 1 we present the theoretical framework of the B$0\\atop{s}$ neutral mesons system. After a general introduction on the Standard Model, we focus on the quantities which are relevant to the Δms measurement and the CP violation phenomena, underlying the details concerning the study of pseudo-scalar to vector vector decays, P → VV, which allow to carry out an angular analysis. A discussion on the implication of the measurements performed in the search of physics beyond the Standard Model is presented. The accelerator facilities and the CDF-II detector are reported in Chapter 2. While describing the detector, more emphasis is given to the components fundamental to perform B physics analyses at CDF. The Chapter 3 is focused on the reconstruction and selection of the data samples. The Chapter starts with a description of the on-line trigger requirements, according to the B$0\\atop{s}$ sample considered, followed by the offline selection criteria implemented to reconstruct B$0\\atop{s}$ semileptonic and hadronic decays, fully and partially reconstructed, for the B$0\\atop{s}$ mixing analysis, as well as the B$0\\atop{s}$ → J/ψφ decay mode for the angular analysis. The subsequent Chapter 4 is dedicated to the revision of the technical ingredients needed in the final analyses. The B$0\\atop{s}$ mixing elements are firstly described. The methodology historically used in the oscillation searches, the 'amplitude scan', is here introduced together with the calibration of the proper-decay-time resolution and the flavor tagging algorithms, in particular a closer examination of the same-side tagger performances is given. The B$0\\atop{s}$ → J/ψφ angular analysis elements description then follows, focusing on the performances and the eventual differences with respect to the B$0\\atop{s}$ oscillation search. The final results of the analyses are obtained with the use of an un-binned likelihood fitting framework: Chapter 5 presents the general principles behind this methodology and a description of both the maximum likelihood fitters employed. Chapter 6 contains the conclusive results on the B$0\\atop{s}$ analyses. They are presented in an historical fashion: the measurement of the B$0\\atop{s}$ oscillation frequency is followed by the first flavor tagged ΔΓs and βs measurements. The impact and the constraints on the parameters of the flavor model is part of the discussion in the Chapter. As cross-check of the B$0\\atop{s}$ angular analysis, the B$0\\atop{s}$ → J/ψK*0 decay mode has been additionally studied. Its angular analysis shows a competitive sensitivity with the B factories in measuring the parameters which define the decay. Not only this contributes to enforce the reliability of the entire framework, but it constitutes an excellent result by itself. Thus, we devote the entire Chapter 7 to the sole discussion of the angular analysis of the B$0\\atop{s}$ → J/ψK*0 decay mode.

  15. Necessary actions in order to reduce the probability for a region being without power supply for a longer period; Tiltak for aa redusere sannsynligheten for at et omraade er stroemloest over lang tid

    Ulsberg, Helge; Gaaserud, Oeystein; Loneland, Knut; Kristensen, Roar

    2009-07-01

    In January 2007 the inhabitants of the municipality of Steigen in Nordland county experienced a protracted power failure in the main power supply. A storm led to a breakdown on one of the two power supply lines which serve the region. The remaining power line turned out to be in such a bad condition that it did not stand up to the increased load. In November 2007 an excavator caused serious damage to the power distribution network in Oslo. The railways in the Eastern central region of Norway including Oslo came to a total halt. Critical societal functions were cut off from data communication for 10 hours. Both cases aroused considerable media interest and clearly demonstrated society's dependency of a reliable power supply. During the summer of 2007 NVE Norwegian Water Resources and Energy Directorate initiated the establishment of a joint project group, with representatives from Statnett SF (the main national grid owner and operator), the Directorate for Civil Defence and Emergency Planning and NVE. The objective was to analyse and assess the need for relevant improvement in procedures, guidance and regulations, in order to reduce the possibility of a similar incident, meaning a region without power supply over a longer period. The procedure project has a main limitation where it meets with the responsibilities of the power network suppliers. The basis for the project activities are the Energy Act and the Act on Supervision of Electricity Installations and Networks with further regulations. The project will sum up conditions and elements which are of vital importance when it comes to reduce the possibility of an extensive power failure: The correct and solid planning of the plants; The control during the construction process and after the finalization; The systematic control and implementation of maintenance and refurbishment; The updating of the plants in order to ensure delivery quality and safety level; Develop risk and vulnerability analyses for extreme situations; Use risk and vulnerability analyses for preventive and curtailing actions; Build up preparedness for worst-case situations. In the case of an extensive power failure the following measures may be decisive: The re-establishment effort must be based on a realistic time schedule; Assess fast engine-generator running versus extensive repair works; Prioritize critical end-users; Good information preparedness and active crisis communication. As a matter of form the project wishes to emphasize that end-users who are critically dependant of a continuous power supply must make provision for this themselves. As one of several results the project work has given a set of suggestions for improvement. Some suggestions have already been implemented or are in progress, while others demand further elaboration. The suggestions have been presented to sectoral organisations and the regional managers of the power supply authorities. The participation of sectoral organisations is important in several areas. The project suggests the following actions: The establishment of a supervision body between DSB and NVE in order to increase the efficiency of supervision. The establishment of a working group which will develop guidance concerning risk- and vulnerability analyses. The establishment of a working group which will develop thematic guidance on circuit protection. The establishment of a working group which will develop thematic guidance on control installations. Assess the need for production of information packages concerning law, provisions, guides and regulations. Clarify the need for competence groups on the subject circuit protection. Carry out supervision in the internal control systems of selected companies to create a basis for possible guidance and counselling. Assess the possibility of establishing an NVE project in order to get a total overview of the engine generators in possession of the power supply authorities and other generators of importance for the network. Assess the possibility of establishing a similar DSB-project in order to get an overview of available generators in the private area, as well as an overview of the need with critical societal users. Assess the need for closer supervision from the side of DSB concerning control and function testing. Increase the intensity of supervision from the public authorities involved. (EW)

  16. Hamman Philippe, Blanc Christine, 2009, Sociologie du développement urbain durable. Projets et stratégies métropolitaines françaises, Bruxelles, P.I.E Peter Lang, 260p.

    Bruno Villalba

    2009-10-01

    Full Text Available Cet ouvrage, réalisé en collaboration avec Flore Henninger, préfacé par Viviane Claude et postfacé par Corinne Larrue, est dirigé par Philippe Hamman (maître de conférences en sociologie au département d’urbanisme de l’UFR de sciences sociales, pratiques sociales et développement de l’université de Strasbourg ; il a dirigé, en 2008, Penser le développement durable urbain : regards croisés, Paris, L’Harmattan et Christine Blanc (sociologue et urbaniste, chargée d’études au Centre de recherche...

  17. New records of Cotylea (Polycladida, Platyhelminthes) from Lizard Island, Great Barrier Reef, Australia, with remarks on the distribution of the Pseudoceros Lang, 1884 and Pseudobiceros Faubel, 1984 species of the Indo-Pacific Marine Region.

    Marquina, Daniel; Aguado, M Teresa; Noreña, Carolina

    2015-09-18

    In the present work eleven polyclad species of Lizard Island are studied. Seven of them are new records for this locality of the Australian coral reef and one is new to science, Lurymare clavocapitata n. sp. (Family Prosthiostomidae). The remaining recorded species belong to the genera Pseudoceros (P. bimarginatus, P. jebborum, P. stimpsoni, P. zebra, P. paralaticlavus and P. prudhoei) and Pseudobiceros (Pb. hancockanus, Pb. hymanae, Pb. flowersi and Pb. uniarborensis). Regardless of the different distribution patterns, all pseudocerotid species show brilliant colours, but similar internal morphology. Furthermore, differences in the form and size of the stylet are characteristic, because it is a sclerotic structure that is not affected during fixation. In Pseudoceros, the distance between the sucker and the female pore also differs among species. These features do not vary enough to be considered as diagnostic, but they provide information that can help to disentangle similarly coloured species complexes. A key of the genera Pseudoceros and Pseudobiceros of the Indo-Pacific region is provided, in order to facilitate the identification of species from this area.

  18. ”Den lange rejse …” – metaforiske betydningslag i filmmediet. En analyse af Aarhus Universitets vejlednings-, branding- og rekrutteringskampagne 2012 [“The Long Journey…” – Metaphorical Meanings and Branding in Film

    Christine Petersen

    2014-12-01

    Full Text Available This article investigates the implicit metaphorical meanings and motifs in a short campaign film and analyses the ways in which the narrative and sequential structure of the film unfolds itself in order to generate these underlying layers of meanings. The short film ‘Tænk. Hvis det er dig’ (‘Think. If It Were You’, which serves as the specific case of this study, was part of Aarhus University’s 2012 branding and student recruitment campaign, which also consisted of a dedicated website and study guidance materials. Using the theoretical insights of the Conceptual Metaphor Theory, as proposed by George Lakoff and Mark Johnson in their 1980 book Metaphors We Live By, as a framework for our analysis, we examine the nature of the metaphor(s used in the film and establish that an implicit metaphorical understanding of ‘education as a journey’ is present throughout the film. In the article, we argue for an interpretation of the underlying narrative metaphor as ‘education as a modern Grand Tour’ – a metaphor that connotes (often culturally-anchored concepts and notions such as ‘general education’ (Bildung, which includes academic knowledge and skills as well as the notion of the university as a social context, ‘personal development’ and ‘citizenship’. Through this analysis and the explication of underlying structurally- and visually-established metaphorical meanings, we wish to demonstrate how an originally linguistic and textual concept of metaphor as developed in the Conceptual Metaphor Theory can contribute to an in-depth understanding of visually-based cinematic and narrative techniques.

  19. How much radiation dose, to whom? Long-term storage, surveillance, retrieval and long processes cause additional dose to employees; Wie viel Strahlendosis fuer wen? Lange Lagerung, Offenhaltung und ein langer Entsorgungsprozess bedeuten zusaetzliche Dosis fuer Beschaeftigte

    Walther, Clemens [Hannover Univ. (Germany). Inst. fuer Radiooekologie und Strahlenschutz; Riemann, Moritz [Kiel Univ. (Germany). Lehrstuhl fuer Philosophie und Ethik der Umwelt

    2017-09-01

    In the case of final nuclear waste disposal there are concurrent interests with respect to radiation protection: The realization of a disposal option with minimum required follow-up care needs time causing additional radiation exposure for the employees, also the option of long-term storage, surveillance and retrieval possibilities cause additional dose to employees. The contribution discusses possible consideration of requests for the different options.

  20. Long lines Co2. Results from over 20 years of research on Co2 capture. Thematic booklet; Lange spor CO2. Resultater fra over 20 aar med forskning paa CO2. Temahefte

    NONE

    2011-07-01

    CLIMIT program aims to accelerate commercialization of carbon sequestration through economic stimulation of research, development and demonstration. This publication focuses on documenting results of research on carbon sequestration both through the CLIMIT program and other research which can be traced back to the 1980s. This publication is part of a comprehensive plan for documentation of results.(eb)

  1. Impact écotoxicologique de mélanges de pesticides sur des fonctions microbiennes des sols : apport d’une prise en compte écologique dans l’évaluation des risques

    Devers-Lamrani, Marion; Rouard, Nadine; Cheviron, Nathalie; Grondin, Virginie; Martin-Laurent, Fabrice

    2015-01-01

    L’utilisation de pesticides permet d’assurer la qualité de la production végétale mais elle contribue à la contamination des sols et des eaux et produit des effets sur des organismes noncibles. L’évaluation des risques requièrent actuellement une meilleure prise en compte des effets des pesticides sur le fonctionnement des écosystèmes. Or, les démarches et indicateurs classiques manquent de représentativité écologique. La fonction microbienne de biodégradation des pesticides est essentielle c...

  2. 15 years return transport of vitrified high-level waste from France. The long way from La Hague to Gorleben; 15 Jahre Rueckfuehrung von verglasten hochaktiven Abfaellen aus Frankreich. Der lange Weg von La Hague nach Gorleben

    Horn, Thomas [GNS Gesellschaft fuer Nuklear Service mbH, Essen (Germany)

    2012-11-01

    The operators of German nuclear power plants have contracts since 1977 with the French company AREVA NC (former COGEMA) and since 1980 with the British company NDA (former BNFL) for reprocessing of spent nuclear fuel. Since July 2005 the delivery of irradiated fuel element into a reprocessing plant is prohibited. Until 2005 fuel elements with about 6.080 tSM were shipped abroad, about 5.309 tSM to France. The contribution deals with the history of the transports from La Hague to Gorleben, including the contamination problems in 1988 that caused restrictions by the German authorities. A catalogue of safety requirements had to be fulfilled for the allowance of further return transports. The development of appropriate transport casks to cope with changing heat generation of the high-level waste is described. During the complete transport cycle extensive radiological measurements were performed. By the end of 2011 the HAW (high-level waste) glass coquilles were completely returned to Gorleben.

  3. 100eme anniversaire de la théorie de la relativité Une BD romande : Mélanges Einstein (Albert) et l'histoire de la physique

    Tesnier, Grégory

    2005-01-01

    2005 has been delcared "Year of Physics" by UNESCO and ONU to celebrate the 100th anniversary of the theory of relativity, elaborated by Einstein (who lived in Bern). To hon. Einstein, an historical comic strip has been published (1 page)

  4. Laurent Mermet (dir., Étudier des écologies futures. Un chantier ouvert pour les recher­ches prospectives environnementales. P.I.E.-Peter Lang, EcoPolis. Vol. 5, 2005, 411 p.

    Magalie Franchomme

    2006-03-01

    Full Text Available L’ouvrage ici proposé est le résultat d’un travail d’équipe réunissant cinq chercheurs et doctorants : Laurent Mermet (coordinateur, professeur, Xavier Poux (chercheur associé, Hubert Kieben, Sébastien Treyer et Ruud Van der Helm (doctorants. Ces derniers ont fonction­né durant 5 ans (1999-2003 au sein d’un pole prospective à l’intérieur du groupe de recherche en gestion sur les territoires et l’environnement (RGTE. Ce programme appuyé par l’ENGREF (Ecole Nationale du Génie Rural des Eau...

  5. Altijd wat te doen bij het sluisje van Dorkwerd

    den Hollander, Franciscus; van Dam, Vanessa; Langenberg, Sjaak

    2006-01-01

    Ooggetuigeverslagen van 84 Nederlandse auteurs die op 1 september 2006 van 11.00 tot 17.00 uur langs de 118 kilometer lange vaarroute van Lemmer naar Delfzijl (Prinses Margrietkanaal, Van Starkenborg-kanaal, Eemskanaal) zaten.

  6. Lapsesuu või PR-guru? / Airi Ilisson

    Ilisson, Airi, 1980-

    2007-01-01

    Justiitsminister Rein Lang on autori hinnangul tuntud oma ootamatute arvamustega. CV. Vt. samas: Skandaal: Kuidas Lang politseid ja allilma seostades tormi tekitas. Kommenteerivad: Hans H. Luik, Hannes Astok, Laine Jänes, Rein Kilk ja Ulvi Kuusk

  7. Experiment list: SRX189420 [Chip-atlas[Archive

    Full Text Available ription=lymphoblastoid cell line, De Lange phenotype; developmental delay; profound retardation; seizures; 3 cousins...ymphoblastoid cell line, De Lange phenotype; developmental delay; profound retardation; seizures; 3 cousin

  8. 97 miljonit aastaga maha mängitud / Kaisa Tahlfeld

    Tahlfeld, Kaisa

    2008-01-01

    Olympic EG kolmanda kvartali kasum langes 94%, 7,4 miljonile kroonile. Vt. samas: Kokkuhoiukava raskuskese langes kolmandasse kvartalisse. Diagramm: Käive ja kasum. Kommenteerib LHV analüütik Sten Pisang

  9. O Novo Partido Anticapitalista francês: nova batalha numa antiga guerra?

    Leandro de Oliveira Galastri

    2009-11-01

    Full Text Available

    lang="EN-US">Estelang="EN-US"> lang="EN-US">artigolang="EN-US"> pretende lang="EN-US">apresentarlang="EN-US">, de lang="EN-US">formalang="EN-US"> lang="EN-US">brevelang="EN-US">, algumas lang="EN-US">questõeslang="EN-US"> relativas à lang="EN-US">formaçãolang="EN-US"> do lang="EN-US">Novolang="EN-US"> lang="EN-US">Partidolang="EN-US"> lang="EN-US">Anticapitalistalang="EN-US"> lang="EN-US">francêslang="EN-US">, o NPA. Criado no início de 2009 a partir da dissolução da tradicional organização trotskista Liga Comunista Revolucionária (LCR, o NPA surge como uma agremiação descentralizada, cujo objetivo é aglutinar em seu seio diversas correntes e movimentos políticos de esquerda, no intuito de construir uma resistência mais efetiva às forças do capital.

  10. An Inference Language for Imaging

    Pedemonte, Stefano; Catana, Ciprian; Van Leemput, Koen

    2014-01-01

    We introduce iLang, a language and software framework for probabilistic inference. The iLang framework enables the definition of directed and undirected probabilistic graphical models and the automated synthesis of high performance inference algorithms for imaging applications. The iLang framewor...

  11. Balancing the people, profit and planet dimensions in international marketing channels : a study on coordinating mechanisms in the Nile perch channel from Lake Victoria

    Kambewa, E.

    2007-01-01

    Keywords: people, profit, planet, marketing channels, contracts, sustainability, quality,LakeVictoria, conjointlang=EN-GB style='mso-ansi-language:NL'>lang=EN-GB style='mso-ansi-language:EN-GB'>analysislang=EN-GB

  12. Educations in Ethnic Violence: Identity, Educational Bubbles, and Resource Mobilization

    Lange, Matthew

    2011-01-01

    In "Educations in Ethnic Violence", Matthew Lange explores the effects education has on ethnic violence. Lange contradicts the widely-held belief that education promotes peace and tolerance. Rather, Lange finds that education commonly contributes to aggression, especially in environments with ethnic divisions, limited resources, and…

  13. Innovations in microspore embryogenesis in Indonesian hot pepper (Capsicum annuum L.) and Brassica napus L.

    Supena, E.D.J.

    2004-01-01

    Hot pepper (lang=EN-US style='mso-bidi-font-size:12.0pt'>Capsicum annuumlang=EN-US style='mso-bidi-font-size:12.0pt;font-style:normal'>L.) is the most important vegetable inlang=EN-US

  14. Algasid Henno "Mina olin siin" järgi tehtava filmi võtted

    2007-01-01

    Eile algasid noortefilmi "Mina olin siin" võtted. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos

  15. Jõgeva bussijaam sai liimpuidu kasutamise eripreemia

    2009-01-01

    Konkursil Eesti Parim Puitehitis 2009 sai liimpuidu kasutamise eripreemia Jõgeva bussijaam, arhitektid Andres Lunge ja Mait Lauri firmast Lunge & Co OÜst. Peapreemia pälvis suvila Jõelähtmel, arhitekt Sten Ader büroost SKAD Arhitektid. Loetletud ka teisi auhinnalistele kohtadele tulnud töid

  16. Lihtsamatele töödele napib ladudes ja terminalides tööjõudu / Rivo Sarapik

    Sarapik, Rivo, 1981-

    2005-01-01

    Ilmunud ka: Delovõje Vedomosti 2. nov. lk. 17. Teravnemas on terminali- ja laotööliste puudus, sest lihttöödele on keeruline töötajaid leida. Kommenteerivad: Andres Leht, Annika Lootus, Mait Miller ja Margus Tammaru

  17. Tartu kalendritootja investeeris uude tehasesse 100 miljonit / Kadrin Karner

    Karner, Kadrin

    2008-01-01

    Ilmunud ka: Delovõje Vedomosti 24. sept. lk. 5. Tartus avatud Ajasto Diary Groupi kalendritehasesse investeeriti üle 100 miljoni krooni, mille tasuvuspiiriks loeb ettevõte umbes kümme aastat. Vt. samas: Mis on mis: Ajasto Diary Group; Kommenteerivad: Mait Puusepp, Andras Metsa, Kadrin Karner

  18. Kuidas tuua Eestisse Tiger Woods / Raul Ranne

    Ranne, Raul

    2008-01-01

    Reaalselt arvestades on tõenäosus, et Eestit väisab golfistaar Tiger Woods, muidugi olematu. Teoreetiliselt on see siiski võimalik. Vestlusest Jõelähtme golfiväljakut opereeriv Estonian Golf Country Clubi presidendi Mait Schmidtiga

  19. Absurd on igihaljas / Vaapo Vaher

    Vaher, Vaapo, 1945-

    2006-01-01

    Tutvustus: Camus, Albert. Õnnelik surm / tõlkinud Tanel Lepsoo. Tallinn : Varrak, 2005 ; Metsanurk, Mait. Kreeps / koost. Maire Liivamets. Tallinn : Eesti Raamat, 2005. (Eesti novellivara). Järg: 23. veebr., lk. 27, sisaldab Aivar Kulli kriitikakogu "Kulli pilk" (Ilmamaa, 2005) tutvustust

  20. 101 riigikogulast said valijalt ehmatava liputervituse / Tuuli Koch

    Koch, Tuuli

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke 4. sept. lk. 4. Valija Tiina Talts saatis presidendivalimiste esimese päeva hommikul parlamendiliikmetele kirja, mille juurde oli ümber disainitud Eesti lipp. Vastused saatsid neli saadikut, nende hulgas Mait Klaassen, Jaak Allik, Janno Reiljan

  1. 432 püksipaari Riia kongresside palee fassaadil / Lauri Kärk

    Kärk, Lauri, 1954-

    2000-01-01

    Filmifestivalil "Arsenals" sai parima režissööri kujukese Mait Laas nukufilmi "Teekond Nirvaanasse" eest, teise koha preemia Valentin Kuigi mängufilm "Lurjus" ja Riho Undi nukufilm "Saamuel internetis". Peaauhinna andis loos shoti naisrežissööri Lynne Ramsay mängufilmile "Rotipüüdja" ("Ratcatcher")

  2. Väikeelamine suureks - normaalpere konteinersüsteemis = Small living space made bigger - container system for a typical family

    2009-01-01

    Tutvustatakse Tallinna Tehnikakõrgkooli Arhitektuuri Instituudi arhitektuuri eriala üliõpilaste töid teemal "Väikeelamine suureks - normaalpere konteinersüsteemis". Idee: rahuldada ühesuuruste "konteinerite" baasil ehitatud torn- või ridamajadega väikekorterite nõudlust. Juhendaja: sisearhitekt Mait Summatavet (lk. 60 andmeid M. Summataveti elu ja loomingu kohta)

  3. Põlvas näeb Ove Mustingu filmi / Tiia Allas

    Allas, Tiia

    2006-01-01

    8. jaan. linastub Põlva kultuurikeskuses lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005

  4. Ilma tahtmata ja teadmata paradiisi ehk Arhetüüp eesti moodi / Rein Tootma

    Tootma, Rein

    2006-01-01

    Lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005

  5. Keskmiselt kobe vaatamine / Küllike Rooväli

    Rooväli, Küllike, 1969-

    2004-01-01

    Eesti komöödiafilm "Vanad ja kobedad saavad jalad alla" : režissöör Rando Pettai : operaator Mait Mäekivi : näitlejad Henrik Normann, Madis Milling, Robert Gutman jt. : muusika - ansambel Genialistid : Ruut Pictures 2003

  6. Eesti teadlaste artikkel juutide põlvnemisest jõudis tippajakirja / Marju Himma

    Himma, Marju

    2010-01-01

    Eesti ja Iisraeli teadlaste rühm uuris juutide geneetilist sarnasust üle maailma. Artikkel avaldati rahvusvahelises teadusajakirjas Nature. Uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayevi, Mait Metspalu ja Richard Villems

  7. Karmid mängud / Kristel Raesaar

    Raesaar, Kristel

    2000-01-01

    Tüli puiduärimehega maksis Hansapangale üle 100 miljoni. Lisa: ühed faktid, mitu tõlgendust - Hansapanga kreedidirektor Aivar Rehe, ECT tegevjuhi Arvi Schilfi ja laenu varjamises süüdistatud Hansapanga endise väliskaubanduse finantseerimise osak. juhataja Mait Kolditsa nägemus ECT laenuraha kadumisega seotud sündmustest

  8. The Utility of the Metacognitive Awareness Inventory for Teachers among In-Service Teachers

    Kallio, Heli; Virta, Kalle; Kallio, Manne; Virta, Arja; Hjardemaal, Finn Rudolf; Sandven, Jostein

    2017-01-01

    The purpose of the present study is to explore the utility of the compressed version of the Metacognitive Awareness Inventory for Teachers (MAIT-18) among in-service teachers. Knowledge of teachers' awareness of metacognition is required to support students' self-regulation, with the aim of establishing modern learning methods and life-long…

  9. Inimkatse blondi eesti naise peibutustest Egiptuses / Liivi Shein

    Šein, Liivi

    2006-01-01

    ETVs esilinastus 23. nov. "Eesti lugude" sarjas valminud "1001 öö muinasjutt ehk eesti naiste imelised seiklused Egiptuses" : režissöör Elo Selirand : toimetaja Anne-Mari Neider : operaator Mait Mäekivi : Osakond OÜ 2006

  10. "Riigikogu hoone 90" = "Estonian parliament building 90" / Janno Roos, Andres Labi

    Roos, Janno, 1976-

    2013-01-01

    Eesti Sisearhitektide Liidu 2012. aasta näituse kujunduse preemia pälvinud näitusest (Lossiplats 1A). Kujunduse autorid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Mait Väljas. Graafiline disain: Identity. Sisearhitekti ja ESLi aastapreemiate žürii liikme Mari Kurismaa ning arhitektuuriajaloolase Leele Välja arvamused

  11. Poolsajandi õnnesoovid Jaak Aaviksoole / Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar...[jt.

    2004-01-01

    Mõtteid Tartu Ülikooli rektorist tema 50. sünnipäeva puhul : Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar, Indrek Reimand, Toomas Kiho, Leelo Kriisa, Peeter Olesk, Risto Tammelo, Birute Klaas, Peeter Saari, Andrus Ansip, Mait Klaassen, Marika Kullamaa, Kaupo Bend

  12. Kas meie põllunduskoolid kasvatavad peremehi või sulaseid? / Heino Luiga, Vello Vilu, Kaul Nurm ...[jt.

    2008-01-01

    Küsimusele vastab Räpina aianduskooli direktor Heino Luiga, Järvamaa kutsehariduskeskuse põllumajanduse erialade juhtiv õpetaja Vello Vilu, Eesti talupidajate keskliidu peadirektor Kaul Nurm, Olustvere teenindus- ja maamajanduskooli direktor Arnold Pastak ning maaülikooli rektor Mait Klaassen

  13. Tantsuime: märjaks nutetud Märt Agu saab 8000 uut sõpra / Märt Agu ; intervjueerinud Rein Sikk

    Agu, Märt, 1980-

    2011-01-01

    11. Noorte tantsupeo "Maa ja ilm" üldjuht ja Tallinna Tantsuakadeemia kunstiline juht Märt Agu Tallinna lauluväljakul toimuvast tantsupeost, ülevaatustest, eesti meeste rahvatantsust, oma isast Mait Agust, tema tantsust "Põhjamaa", tantsuõpetaja elukutsest, eesti tantsust, Tallinna Tantsuakadeemiast. Andmeid Märt Agu loomingu kohta

  14. Tudengite nappus seab kõrgkoolid raskustesse / Madis Filippov

    Filippov, Madis

    2008-01-01

    Gümnasistide arvu vähenemine nõuab kõrgkoolide töö ümberhindamist. Arvamust avaldavad Tallinna Ülikooli rektor Rein Raud, Tartu Ülikooli rektor Alar Karis, Eesti Maaülikooli rektor Mait Klaassen, Euroülikooli rektor Jüri Martin, Estonian Business Schooli rektor Peeter Kross ja haridusminister Tõnis Lukas

  15. Lastemuuseum Miia-Milla-Manda = The Miia-Milla-Manda Children's Museum / Margit Mutso

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Koidula 21A asuva hoone restaureerimisest, lastemuuseumi sisekujundusest. Kadrioru Lastepargi paviljoni (arhitekt Villem Seidra, 1937) renoveerimisprojekti tegi arhitekt Katrin Etverk, sisearhitektid ja ekspositsiooni kujundus: Maile Grünberg, Eliina Grünberg (Grünberg oü). Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

  16. Baltika büroo = The Baltika Offices / Margit Mutso

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Veerenni 24 asuvast Baltika büroost. Arhitektuur, bürooruumide kujundus: AB Studio 3, Kolm Pluss Üks Arhitektid. Žürii liige Mait Summatavet žürii hinnangust EK arhitektuuri sihtkapitali 2009. a. sisearhitektuuri preemia pälvinud bürooruumidele

  17. Nõmme Lunastaja kirik = The Saviour's Lutheran Church in Nõmme / Margit Mutso

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Õie 10 asuva kirikuhoone (arhitekt Robert Natus, 1932) restaureerimisest. Arhitekt Fredi-Armand Tomps, sisearhitekt Anne Koppel, ehitusjärelevalve: Rein Joller, ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang EK arhitektuuri sihtkapitali 2009. a. restaureerimispreemia pälvinud hoonele

  18. Toompea komandandimaja = The Commandant's House in Toompea / Margit Mutso

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Toompea 1 asuva hoone restaureerimisest. Arhitekt Raul Vaiksoo, kaasautor Kristo Vaiksoo (Raul Vaiksoo Arhitektuuribüroo), sisearhitektid Priit Põldme, Rita Rahu (SAB Joonprojekt), Raul Vaiksoo, ajaloolased Raul Vaiksoo, Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

  19. Eesti animafilmid Ottawas / M. L.

    M. L.

    2006-01-01

    Ottawa rahvusvahelisel animafilmifestivalil 20.-24. sept. võistlesid Eesti poolt Mati Küti "Une instituut" ja "Vulcain.Cricet", Priit Tenderi "Sõnum naabritele", Ülo Pikkovi "Elu maitse" ja Mait Laasi "Generatsioon". Eesti auhindu ei saanud. Peaauhind täispika animatsiooni eest läks inglasele Phil Mulloy'le filmi "Christied" eest

  20. Võtme ja riiviga tantsufilm / Kristiina Garancis

    Garancis, Kristiina, 1969-

    2005-01-01

    Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island 2005