WorldWideScience

Sample records for animal reproductive processes

  1. Impact of Marine Drugs on Animal Reproductive Processes

    OpenAIRE

    Elisabetta Tosti; Francesco Silvestre

    2009-01-01

    The discovery and description of bioactive substances from natural sources has been a research topic for the last 50 years. In this respect, marine animals have been used to extract many new compounds exerting different actions. Reproduction is a complex process whose main steps are the production and maturation of gametes, their activation, the fertilisation and the beginning of development. In the literature it has been shown that many substances extracted from marine organisms may have pro...

  2. Glycobiology of Reproductive Processes in Marine Animals: The State of the Art

    Directory of Open Access Journals (Sweden)

    Maria Costantini

    2012-12-01

    Full Text Available Glycobiology is the study of complex carbohydrates in biological systems and represents a developing field of science that has made huge advances in the last half century. In fact, it combines all branches of biomedical research, revealing the vast and diverse forms of carbohydrate structures that exist in nature. Advances in structure determination have enabled scientists to study the function of complex carbohydrates in more depth and to determine the role that they play in a wide range of biological processes. Glycobiology research in marine systems has primarily focused on reproduction, in particular for what concern the chemical communication between the gametes. The current status of marine glycobiology is primarily descriptive, devoted to characterizing marine glycoconjugates with potential biomedical and biotechnological applications. In this review, we describe the current status of the glycobiology in the reproductive processes from gametogenesis to fertilization and embryo development of marine animals.

  3. Reproductive interference between animal species.

    Science.gov (United States)

    Gröning, Julia; Hochkirch, Axel

    2008-09-01

    Although sexual interactions between species (reproductive interference) have been reported from a wide range of animal taxa, their potential for determining species coexistence is often disregarded. Here, we review evidence from laboratory and field studies illustrating that heterospecific sexual interactions are frequently associated with fitness loss and can have severe ecological and evolutionary consequences. We define reproductive interference as any kind of interspecific interaction during the process of mate acquisition that adversely affects the fitness of at least one of the species involved and that is caused by incomplete species recognition. We distinguish seven types of reproductive interference: signal jamming, heterospecific rivalry, misdirected courtship, heterospecific mating attempts, erroneous female choice, heterospecific mating, and hybridization. We then discuss the sex-specific costs of these types and highlight two typical features of reproductive interference: density-dependence and asymmetry. Similar to competition, reproductive interference can lead to displacement of one species (sexual exclusion), spatial, temporal, or habitat segregation, changes in life history parameters, and reproductive character displacement. In many cases, patterns of coexistence might be shaped by reproductive interference rather than by resource competition, as the presence of a few heterospecifics might substantially decrease reproductive success. Therefore, interspecific sexual interactions should receive more attention in ecological research. Reproductive interference has mainly been discussed in the context of invasive species or hybrid zones, whereas its influence on naturally-occurring sympatric species pairs has rarely been addressed. To improve our knowledge of the ecological significance of reproductive interference, findings from laboratory experiments should be validated in the field. Future studies should also focus on ecological mechanisms, such

  4. Reproduction (II): Human Control of Reproductive Processes

    Science.gov (United States)

    Jost, Alfred

    1970-01-01

    Describes methods of intervening in reproduction of animals and humans (artificial insemination, contraception, ovular and blastodisc transplants, pre selection of sex, cloning) and discusses the social implications of their use with humans. (AL)

  5. Stress and reproduction in farm animals

    International Nuclear Information System (INIS)

    Stress reduces reproductive efficiency in farm animals. Regulators of hypothalamus-pituitary-adrenal (HPA) activity such as CRV, AVP, ACTH and cortisol have deleterious effects on both GnRH and LH secretion. Chronic stressors, such as under-nutrition, can enhance HPA activity which probably results in a greater influence on the mechanisms controlling reproductive function. (author). 30 refs

  6. Neotenic reproduction in various animal groups

    OpenAIRE

    Nevěčný, Karel

    2012-01-01

    The aim of this work is to collect information about neoteny (i. e. reproduction of animals in the larval stage to adult without metamorphosis) that describe the reproduction and assess the representation, if found more groups of animals in which it occurs. The basic method was searching various sources, sorting and analyzing. It is a compilation of work to prepare review. The sources of information were professional articles and books of Czech and foreign, including some Internet resource...

  7. Laparoscopy and ultrasonography in animal reproduction research

    International Nuclear Information System (INIS)

    This paper reviews the applications of laparoscopy and ultrasonography in the Animal Reproduction Laboratory at the University Pertanian Malaysia during the past decade. Laparoscopy was used for the study of ovarian function in cattle and buffalo, the determination of ovulation rates in sheep and goat and intrauterine insemination of sheep. More recently ultrasonography has proved a valuable diagnostic tool for pregnancy diagnosis in cattle, buffalo, sheep and goats and for monitoring and assessing the superovulatory response to gonadotropins in bovine embryo transfer programmes. The cost of equipment is no more than the cost of the basic equipment in a radioimmunoassay laboratory. These techniques are easily mastered and no special precautions are needed for their use under tropical conditions. It is concluded that laparoscopy and ultrasonography could make significant contributions to strengthen research in animal reproduction in Asia. (author). 18 refs

  8. Assisted Reproductive Techniques in Farm Animal - From Artificial Insemination to Nanobiotechnology

    OpenAIRE

    O P Verma; Kumar, R.; Kumar, A.(State University of New York at Buffalo, Buffalo, USA); Chand, S

    2012-01-01

    It has become evident that advances in farm animal reproduction have become increasingly dependent on advance scientific research in addition to an understanding of the physiological processes involved in reproduction. The use of assisted reproductive techniques (ART) has helped owners to produce offspring from valuable farm animals that were considered infertile using standard breeding techniques. This chapter constitutes an update of recent developments in the field of assisted reproduction...

  9. Current and future assisted reproductive technologies for mammalian farm animals.

    Science.gov (United States)

    Hansen, Peter J

    2014-01-01

    Reproduction in domestic animals is under control by man and the technologies developed to facilitate that control have a major impact on the efficiency of food production. Reproduction is an energy-intensive process. In beef cattle, for example, over 50 % of the total feed consumption required to produce a unit of meat protein is consumed by the dam of the meat animal (Anim Prod 27:367-379, 1978). Sows are responsible for about 20 % of the total feed needed to produce animals for slaughter (Adv Pork Prod 19:223-237, 2008). Accordingly, energy input to produce food from animal sources is reduced by increasing number of offspring per unit time a breeding female is in the herd. Using beef cattle as an example again, life-cycle efficiency for production of weaned calves is positively related to early age at puberty and short calving intervals (J Anim Sci 57:852-866, 1983). Reproductive technologies also dictate the strategies that can be used to select animals genetically for traits that improve production. Of critical importance has been artificial insemination (AI) (Anim Reprod Sci 62:143-172, 2000; Stud Hist Philos Biol Biomed Sci 38:411-441, 2007; Reprod Domest Anim 43:379-385, 2008; J Dairy Sci 92:5814-5833, 2009) and, as will be outlined in this chapter, emerging technologies offer additional opportunities for improvements in genetic selection. Given the central role of reproduction as a determinant of production efficiency and in genetic selection, improvements in reproductive technologies will be crucial to meeting the challenges created by the anticipated increases in world population (from seven billion people in 2011 to an anticipated nine billion by 2050; World population prospects: the 2010 revision, highlights and advance tables. Working Paper No. ESA/P/WP.220, New York) and by difficulties in livestock production wrought by climate change (SAT eJournal 4:1-23, 2007).The purpose of this chapter will be to highlight current and emerging reproductive

  10. Endocrine Disruptors in Domestic Animal Reproduction: A Clinical Issue?

    OpenAIRE

    Magnusson, Ulf; Persson, Sara

    2015-01-01

    Contents The objective of this review was to discuss whether endocrine disruption is a clinical concern in domestic animal reproduction. To that end, we firstly summarize the phenomenon of endocrine disruption, giving examples of the agents of concern and their effects on the mammalian reproductive system. Then there is a brief overview of the literature on endocrine disruptors and domestic animal reproduction. Finally, the clinical implications of endocrine disruptors on the reproductive sys...

  11. Animal reproduction and physiology: from basis to application

    Institute of Scientific and Technical Information of China (English)

    GUI JianFang

    2010-01-01

    @@ Animal reproduction and physiology is one of the traditional subjects in biology, and also one of the most rapidly developing fields because it is related to human food requirements.Along with advances in the life sciences and biotechnology, animal reproduction and physiology has achieved new theoretical developments and potential applications.

  12. The role of pheromones and biostimulation in animal reproduction.

    Science.gov (United States)

    Rekwot, P I; Ogwu, D; Oyedipe, E O; Sekoni, V O

    2001-03-30

    It is now known that pheromonal communication plays an important role in mammalian behaviour and reproductive processes. Chemical communication with pheromones is one means of transmitting such information. In mammals, signalling and priming pheromones are thought to act either singly or in combination through olfaction, auditory, visual (sight) or tactile stimuli. Pheromones are air-borne chemical substances ("signals") released in the urine or feces of animals or secreted from cutaneous glands that are perceived by the olfactory system and that elicit both behavioural and endocrine responses in conspecifics. Extensive studies in insects, rodents, swine, sheep, goats and cattle have established the importance of pheromones in the strong influence exerted by the male on reproductive activity in the female. There is a pheromone produced by the queen honey bee, which has two functions: inhibition of queen rearing and suppression of oogenesis in workers and in addition attracts drones during nuptial flight. It has also been demonstrated that the urine of male mice, rats, feral species and other wild rodents contains a priming pheromone that is responsible for hastening puberty in the females. Pheromones in the wool, wax and urine of a ram are sufficient to stimulate ewes to ovulate, while the buck has a strong characteristic seasonal odor and a buck jar containing the odor of the buck can be used as an aid in the detection of oestrus in does. The mere presence of the boar at the time of insemination of the sow improves sperm transport and ovulation, while the presence of the vasectomised bull has been reported to hasten the onset of puberty in heifers and also early resumption of ovarian activity in cattle following parturition. The role of pheromones in bovine reproduction is not as clearly defined as in sheep, goats and swine. Pheromones and other allelomimetic cues can exert profound effects on reproductive activity via the hypothalamic system that generates pulses

  13. Interaction of environment and reproductive processes in cattle

    International Nuclear Information System (INIS)

    Effects of environment on reproductive processes of female cattle are described. Variation in fertility responses is divided into environmental and genetic effects. Environmental effects are defined as all effects non-genetic, and emphasis is placed on the quantitation of various climatic measurements (e.g. maximum environmental temperature) associated with reproductive performance. Sensitivities of various reproductive events to thermal stress are defined and include such responses as: reproductive behaviour; hormonal balance related to both reproductive events and metabolic adaptations; alterations in uterine blood flow; embryonic death; conceptus development; placental function; and restoration of postpartum reproductive function. Also discussed are several management strategies to improve animal productivity, including environmental modification and the potential for genetic development of less heat-sensitive animals. (author)

  14. "Feeling the force" in reproduction: Mechanotransduction in reproductive processes.

    Science.gov (United States)

    Evans, Janice P; Leppert, Phyllis C

    2016-05-01

    Reproductive biologists are well-versed in many types of biochemical signaling, and indeed, there are almost innumerable examples in reproduction, including steroid and peptide hormone signaling, receptor-ligand and secondary messenger-mediated signaling, signaling regulated by membrane channels, and many others. Among reproductive scientists, a perhaps lesser-known but comparably important mode of signaling is mechanotransduction: the concept that cells can sense and respond to externally applied or internally generated mechanical forces. Given the cell shape changes and tissue morphogenesis events that are components of many phenomena in reproductive function, it should be no surprise that mechanotransduction has major impacts in reproductive health and pathophysiology. The conference on "Mechanotransduction in the Reproductive Tract" was a valuable launch pad to bring this hot issue in development, cell biology, biophysics, and tissue regeneration to the realm of reproductive biology. The goal of the meeting was to stimulate interest and increased mechanotransduction research in the reproductive field by presenting a broad spectrum of responses impacted by this process. The meeting highlighted the importance of convening expert investigators, students, fellows, and young investigators from a number of research areas resulting in cross-fertilization of ideas and suggested new avenues for study. The conference included talks on tissue engineering, stem cells, and several areas of reproductive biology, from uterus and cervix to the gametes. Specific reproductive health-relevant areas, including uterine fibroids, gestation and parturition, and breast tissue morphogenesis, received particular attention. PMID:27070825

  15. Laboratory training manual on radioimmunoassay in animal reproduction

    International Nuclear Information System (INIS)

    Reproduction must always be regarded as one of the major limiting factors in animal production and many of the modern methods for improving reproduction rely heavily on the ability to measure hormone levels in blood and milk. This has produced a world-wide demand for laboratory facilities to carry out hormone assays and the need for specialist training to allow these assays to be undertaken. The need to measure nanogram and picogram quantities and the use of radionuclides require a good deal of skill and care and this Manual has been prepared to aid training and provide the sort of information that rarely appears in scientific papers. It represents a further step in the Joint FAO/IAEA Division's series of Laboratory Training Manuals, and has been designed to aid training programmes of the type carried out during the Joint FAO/IAEA Interregional Training Course on Radioimmunoassay and its Application in Research on Animal Reproduction at Cornell University in July 1982. Many of the laboratory exercises described in this Manual are based on those conducted during the course

  16. Assisted Reproductive Techniques in Farm Animal - From Artificial Insemination to Nanobiotechnology

    Directory of Open Access Journals (Sweden)

    O P Verma

    2012-10-01

    Full Text Available It has become evident that advances in farm animal reproduction have become increasingly dependent on advance scientific research in addition to an understanding of the physiological processes involved in reproduction. The use of assisted reproductive techniques (ART has helped owners to produce offspring from valuable farm animals that were considered infertile using standard breeding techniques. This chapter constitutes an update of recent developments in the field of assisted reproduction includes Artificial insemination, Embryo transfer, in vitro fertilization, embryo cryopreservation, Sexing of semen and embryos, cloning, transgenesis, stem cell technology, embryo genomics, micro and nanotechnology has been included. Recently in some of these fields remarkable progress has been made. None the less, imperfections are remaining and sustained efforts will be required to optimize existing and invent new technologies. Before referring an animal for an ART, the practitioner should be able to identify the underlying cause of subfertility of that animal. Knowing the complexity as well as the risks of these techniques, enables practitioners to refer a sub-fertile animal to the least complex and most appropriate and successful ART that can overcome specific causes of infertility. [Vet. World 2012; 5(5.000: 301-310

  17. Contributions of an animal scientist to reproductive biology.

    Science.gov (United States)

    Bazer, Fuller W

    2011-08-01

    I became interested in biology as an undergraduate in a premedical curriculum but developed a passion for the field of reproductive biology because of a course in physiology of reproduction taken to meet requirements for admission to veterinary school. My career path changed, and I entered graduate school, obtained the Ph.D., and have enjoyed an academic career as a reproductive biologist conducting research in uterine biology and pregnancy in animal science departments at the University of Florida and at Texas A&M University. However, I have never allowed academic boundaries to interfere with research and graduate education as that is contrary to collegiality, the cornerstone of great universities. I consider that my major contributions to science include 1) identification of proteins secreted by cells of the uterine endometrium that are critical to successful establishment and maintenance of pregnancy; 2) discovery of steroids and proteins required for pregnancy recognition signaling and their mechanisms of action in pigs and ruminant species; 3) investigation of fetal-placental development and placental transport of nutrients, including water and electrolytes; 4) identification of linkages between nutrition and fetal-placental development; 5) defining aspects of the endocrinology of pregnancy; and 6) contributing to efforts to exploit the therapeutic value of interferon tau, particularly for treatment of autoimmune diseases. My current studies are focused on the role of select nutrients in the uterine lumen, specifically amino acids and glucose, that affect development and survival of the conceptus and translation of mRNAs and, with colleagues at Seoul National University, gene expression by the avian reproductive tract at key periods postovulation. Another goal is to understand stromal-epithelial cell signaling, whereby progesterone and estrogen act via uterine stromal cells that express receptors for sex steroids to stimulate secretion of growth factors (e

  18. Animation of boom failure processes

    International Nuclear Information System (INIS)

    Computer animations of oil boom failure mechanisms were discussed. The animations are useful in demonstrating the transient processes of boom failure. They consist of a series of images obtained from the graphical output of a computational fluid dynamics program, FLUENT, while the modeling is based on boom failure experiments carried out in flowing water channels. The animations can be viewed on a PC running under Windows '95. Three types of failures are presented, i. e. drainage failure, droplet entrainment and critical accumulation. 11 refs., 3 figs

  19. Telocytes in female reproductive system (human and animal).

    Science.gov (United States)

    Aleksandrovych, Veronika; Walocha, Jerzy A; Gil, Krzysztof

    2016-06-01

    Telocytes (TCs) are a newly discovered type of cell with numerous functions. They have been found in a large variety of organs: heart (endo-, myo-, epi- and pericardium, myocardial sleeves, heart valves); digestive tract and annex glands (oesophagus, stomach, duodenum, jejunum, liver, gallbladder, salivary gland, exocrine pancreas); respiratory system (trachea and lungs); urinary system (kidney, renal pelvis, ureters, bladder, urethra); female reproductive system (uterus, Fallopian tube, placenta, mammary gland); vasculature (blood vessels, thoracic duct); serous membranes (mesentery and pleura); and other organs (skeletal muscle, meninges and choroid plexus, neuromuscular spindles, fascia lata, skin, eye, prostate, bone marrow). Likewise, TCs are widely distributed in vertebrates (fish, reptiles, birds, mammals, including human). This review summarizes particular features of TCs in the female reproductive system, emphasizing their involvement in physiological and pathophysiological processes. PMID:27060783

  20. Radioisotopic techniques for the study of reproductive physiology in domestic animals: 1. Assay procedures

    International Nuclear Information System (INIS)

    The recent introduction of tracer techniques, such as competitive protein binding assay and radioimmunoassay for measuring peripheral blood plasma levels of hormones in the ng and pg range in large domestic animals, has greatly increased our knowledge of the reproductive physiology of these species. The development of these competitive radioassay techniques has allowed assays to be carried out on small amounts of plasma which, in turn, has allowed serial sampling of blood to be done in the same animal; the result has been a better understanding of the dynamics of reproductive endocrine function. The assay procedures have allowed the processing of large numbers of samples which enables the cost of each analysis to be of reasonable price. It is also worth emphasizing that no radioactive material has to be administered to the animal that is undergoing investigation. The application of competitive radioassay techniques for the measurement of oestrone, oestradiol, progesterone, testosterone and prostaglandins is discussed. These hormones are of significance for the understanding of reproductive procedures in large domestic animals. (author)

  1. Animal models and conserved processes

    Directory of Open Access Journals (Sweden)

    Greek Ray

    2012-09-01

    Full Text Available Abstract Background The concept of conserved processes presents unique opportunities for using nonhuman animal models in biomedical research. However, the concept must be examined in the context that humans and nonhuman animals are evolved, complex, adaptive systems. Given that nonhuman animals are examples of living systems that are differently complex from humans, what does the existence of a conserved gene or process imply for inter-species extrapolation? Methods We surveyed the literature including philosophy of science, biological complexity, conserved processes, evolutionary biology, comparative medicine, anti-neoplastic agents, inhalational anesthetics, and drug development journals in order to determine the value of nonhuman animal models when studying conserved processes. Results Evolution through natural selection has employed components and processes both to produce the same outcomes among species but also to generate different functions and traits. Many genes and processes are conserved, but new combinations of these processes or different regulation of the genes involved in these processes have resulted in unique organisms. Further, there is a hierarchy of organization in complex living systems. At some levels, the components are simple systems that can be analyzed by mathematics or the physical sciences, while at other levels the system cannot be fully analyzed by reducing it to a physical system. The study of complex living systems must alternate between focusing on the parts and examining the intact whole organism while taking into account the connections between the two. Systems biology aims for this holism. We examined the actions of inhalational anesthetic agents and anti-neoplastic agents in order to address what the characteristics of complex living systems imply for inter-species extrapolation of traits and responses related to conserved processes. Conclusion We conclude that even the presence of conserved processes is

  2. Oxidative Stress and Role of Natural Plant Derived Antioxidants in Animal Reproduction

    Institute of Scientific and Technical Information of China (English)

    ZHONG Rong-zhen; ZHOU Dao-wei

    2013-01-01

    The experimental knowledge on the role of oxidative stress, and beneifcial and detrimental effects of plant derived antioxidants in male and female animal reproduction are reviewed in this article. Free radical-induced oxidative stress in animal reproduction causes great loss to livestock industry. Antioxidant therapy has been implicated to be effective in preventing diseases resulted from oxidative stress. Considering the advantages of lower side effects of natural antioxidants than those of synthetic antioxidants, plants or their extracts have been extensively utilized in animals. Although many advances have been gained on application of plant derived antioxidants in alleviating oxidative stress, debatable issues still exist. Because many opposite effects were observed even using plant extracts containing similar bioactive substances in the same animal species. Therefore, plant derived antioxidants, like free radicals, are“double-edged swords”in animal reproduction, representing that they may exhibit beneifcial or detrimental effects in animal reproduction, including spermatogenesis, semen functions, estrous cycles, ovulation, ovary functions, endometrium, embryo development, and pregnancy. Besides dose-dependent manner as an explanation of plant extracts’ dual function, future studies are needed to investigate the mechanism of double-edged actions of plant derived antioxidants in different animal reproduction systems.

  3. Reproduction of an animal model of landmine blast injuries

    Directory of Open Access Journals (Sweden)

    Sen ZHANG

    2014-03-01

    Full Text Available Objective To reproduce an animal model of landmine blast injuries for studying its mechanism and characteristics. Methods Fifteen healthy New Zealand white rabbits (body weight 1.9-2.4 kg were prepared as experimental animals. Punctiform burster was used to simulate the landmine, and it was electrically detonated far away to produce landmine blast injuries on unilateral hind limb of rabbits in upright state. The vital signs before and 5min, 15min, 30min, 45min, 1h, 2h, 3h, 6h, 9h and 12h after injuries were recorded. Autopsy of dead animals was performed immediately and the survivors were sacrificed for pathological examination 6h and 12h after the injury. Macroscopic and microscopic changes in the injured limb and distant organs were observed. Fifteen random adult body weights were generated by random number table, and the explosive energy of M14 landmine (about 29g TNT explosive energy was simulated, to compare the ratio of explosive force equivalent to weight calculated between experimental animals and randomly selected adults. Results No significant change in blood pressure was observed at different time points before and after injuries. A broom-like change was found in the injured limb by the general observation. The subareas and pathological changes of injured limb coincided with the typical limb injuries produced by landmine explosion. Damage in different degrees was found in distant organs, and the wound characteristics and injury of major organs were in accordance with the reports of relevant literature. The ratio of explosive equivalent to weight of experimental animals (0.50±0.04g TNT/kg was similar to that of randomly selected adults (0.51±0.05g TNT/kg. Conclusion The present animal model could simulate the landmine explosive injuries, and may be used in research of landmine explosive injuries. DOI: 10.11855/j.issn.0577-7402.2014.01.14

  4. Animal models of physiologic markers of male reproduction: genetically defined infertile mice

    Energy Technology Data Exchange (ETDEWEB)

    Chubb, C.

    1987-10-01

    The present report focuses on novel animal models of male infertility: genetically defined mice bearing single-gene mutations that induce infertility. The primary goal of the investigations was to identify the reproductive defects in these mutant mice. The phenotypic effects of the gene mutations were deciphered by comparing the mutant mice to their normal siblings. Initially testicular steroidogenesis and spermatogenesis were investigated. The physiologic markers for testicular steroidogenesis were steroid secretion by testes perifused in vitro, seminal vesicle weight, and Leydig cell histology. Spermatogenesis was evaluated by the enumeration of homogenization-resistant sperm/spermatids in testes and by morphometric analyses of germ cells in the seminiferous epithelium. If testicular function appeared normal, the authors investigated the sexual behavior of the mice. The parameters of male sexual behavior that were quantified included mount patency, mount frequency, intromission latency, thrusts per intromission, ejaculation latency, and ejaculation duration. Females of pairs breeding under normal circumstances were monitored for the presence of vaginal plugs and pregnancies. The patency of the ejaculatory process was determined by quantifying sperm in the female reproductive tract after sexual behavior tests. Sperm function was studied by quantitatively determining sperm motility during videomicroscopic observation. Also, the ability of epididymal sperm to function within the uterine environment was analyzed by determining sperm capacity to initiate pregnancy after artificial insemination. Together, the experimental results permitted the grouping of the gene mutations into three general categories. They propose that the same biological markers used in the reported studies can be implemented in the assessment of the impact that environmental toxins may have on male reproduction.

  5. Is Boric Acid Toxic to Reproduction in Humans? Assessment of the Animal Reproductive Toxicity Data and Epidemiological Study Results.

    Science.gov (United States)

    Duydu, Yalçın; Başaran, Nurşen; Ustündağ, Aylin; Aydın, Sevtap; Undeğer, Ulkü; Ataman, Osman Yavuz; Aydos, Kaan; Düker, Yalçın; Ickstadt, Katja; Waltrup, Brita Schulze; Golka, Klaus; Bolt, Hermann Maximilian

    2016-01-01

    Boric acid and sodium borates are classified as toxic to reproduction in the CLP Regulation under "Category 1B" with the hazard statement of "H360FD". This classification is based on the reprotoxic effects of boric acid and sodium borates in animal experiments at high doses. However, boron mediated reprotoxic effects have not been proven in epidemiological studies so far. The epidemiological study performed in Bandırma boric acid production plant is the most comprehensive published study in this field with 204 voluntarily participated male workers. Sperm quality parameters (sperm morphology, concentration and motility parameters), FSH, LH and testosterone levels were determined in all participated employees as the reproductive toxicity biomarkers of males. However, boron mediated unfavorable effects on reproduction in male workers have not been determined even in the workers under very high daily boron exposure (0.21 mg B/kg-bw/day) conditions. The NOAEL for rat reproductive toxicity is equivalent to a blood boron level of 2020 ng/g. This level is higher than the mean blood boron concentration (223.89 ± 69.49 ng/g) of the high exposure group workers in Bandırma boric acid production plant (Turkey) by a factor of 9. Accordingly, classifying boric acid and sodium borates under "Category 1B" as "presumed reproductive human toxicant in the CLP regulation seems scientifically not reasonable. The results of the epidemiological studies (including the study performed in China) support for a down-classification of boric acid from the category 1B, H360FD to category 2, H361d, (suspected of damaging the unborn child). PMID:26511087

  6. The potential of cryopreservation and reproductive technologies for animal genetic resources conservation strategies

    NARCIS (Netherlands)

    Hiemstra, S.J.; Lende, van der T.; Woelders, H.

    2006-01-01

    This chapter focuses on ex situ conservation. An overview of the state of the art cryopreservation and reproductive technology for farm animals and fish is followed by a discussion on the implications of ex situ conservation strategies. Ex situ conservation of genetic material from livestock and fis

  7. [Animal Reproduction and Breeding.] Student Materials. V.A. III. [II-A-1 through II-A-8].

    Science.gov (United States)

    Texas A and M Univ., College Station. Vocational Instructional Services.

    Part of a series of eight student learning modules in vocational agriculture, this booklet deals with animal reproduction and breeding. The topics covered are genetics, animal reproduction, breeding methods, artificial insemination, pregnancy diagnosis, and parturition care. Each section ends with a glossary and a quiz. (PLB)

  8. Knowledge Index for Measuring Knowledge and Adopting Scientific Methods in Treatment of Reproductive Problems of Dairy Animals

    OpenAIRE

    Meena, M.S.; Singh, K.M.; Malik, B. S.; B. S. Meena; Manish Kanwat

    2012-01-01

    Reproductive problems among dairy animals are one of the major causes of loss in dairy sector. These problems can be tackled by imparting appropriate knowledge to the livestock owners. An attempt was made to measure the knowledge of livestock owners by developing a knowledge test on reproductive problems of dairy animals. The study was undertaken in Karnal district of Haryana state, India. Data were solicited from 300 livestock farmers who had at least one milch animal at the time of investig...

  9. Sexuality and reproduction: implications in the process of healthy adolescence

    OpenAIRE

    Adelita Campos Araújo; Valeria Lerch Lunardi; Rosemary Silva da Silveira; Maira Buss Thofehrn; Adrize Rutz Porto; Deisi Cardoso Soares

    2012-01-01

    This study aimed to understand the perceptions of adolescents about their process of healthy adolescence with regard to sexuality and reproduction. This is a qualitative research of exploratory type, involving 10 teenagers, in a state school in southern Rio Grande do Sul, between August and October 2007. To collect the data, were used semi-structured interviews, whose contents were subjected to thematic analysis, emerging the theme: sexuality and reproduction in adolescence. At the data, it w...

  10. Widespread presence of human BOULE homologs among animals and conservation of their ancient reproductive function.

    Directory of Open Access Journals (Sweden)

    Chirag Shah

    2010-07-01

    Full Text Available Sex-specific traits that lead to the production of dimorphic gametes, sperm in males and eggs in females, are fundamental for sexual reproduction and accordingly widespread among animals. Yet the sex-biased genes that underlie these sex-specific traits are under strong selective pressure, and as a result of adaptive evolution they often become divergent. Indeed out of hundreds of male or female fertility genes identified in diverse organisms, only a very small number of them are implicated specifically in reproduction in more than one lineage. Few genes have exhibited a sex-biased, reproductive-specific requirement beyond a given phylum, raising the question of whether any sex-specific gametogenesis factors could be conserved and whether gametogenesis might have evolved multiple times. Here we describe a metazoan origin of a conserved human reproductive protein, BOULE, and its prevalence from primitive basal metazoans to chordates. We found that BOULE homologs are present in the genomes of representative species of each of the major lineages of metazoans and exhibit reproductive-specific expression in all species examined, with a preponderance of male-biased expression. Examination of Boule evolution within insect and mammalian lineages revealed little evidence for accelerated evolution, unlike most reproductive genes. Instead, purifying selection was the major force behind Boule evolution. Furthermore, loss of function of mammalian Boule resulted in male-specific infertility and a global arrest of sperm development remarkably similar to the phenotype in an insect boule mutation. This work demonstrates the conservation of a reproductive protein throughout eumetazoa, its predominant testis-biased expression in diverse bilaterian species, and conservation of a male gametogenic requirement in mice. This shows an ancient gametogenesis requirement for Boule among Bilateria and supports a model of a common origin of spermatogenesis.

  11. Radioisotopic techniques for the study of reproductive physiology in domestic animals: 2. Physiological implications

    International Nuclear Information System (INIS)

    Radioisotopic techniques have been important for studying endocrinological reproductive function in domestic animals. Normal physiological events in which hormone determination has been useful for elucidation of basic concepts include the ovulatory process, cyclic regression of the corpus luteum, hormone requirements for the manifestation of sexual receptivity, establishment of pregnancy and the termination of gestation (parturition). Hormone assays have been useful for understanding the mechanism by which intra-uterine infusion and/or prostaglandin administration in both the cow and the mare shortens the oestrus cycle, namely, through the initiation of regression of the corpus luteum. Endocrine assay has also been valuable in understanding the physiology of premature parturition (abortion), as well as the abnormal prolongation of gestation. Practical uses for hormone assays include the identification of prolonged luteal syndromes such as occur in the mare, cyclic ovarian activity in the absence of sexual receptivity, and follicular or luteal cysts as well as the determination of pregnancy (progesterone in milk or blood) about three weeks post-breeding. (author)

  12. Assessing the animal ethics review process

    DEFF Research Database (Denmark)

    Varga, O.; Sandøe, Peter; Olsson, I.A.S.

    2012-01-01

    Although animal experiments play an important role in biomedical research, their use is ethically challenging. Primarily in Europe, North America and Australasia ethics committees are set up to control the animal use in science. Project approval is usually decided on a case-by-case basis with focus...... on ensuring that the animals are caused a minimum of harm relative to the possibility of achieving beneficial results. Even though rules in this area are reasonably uniform there seems to be significant room for differences, individual and culturally based, between ethics committees concerning how the rules...... are applied. Our aim was to conduct a review of empirical studies of the different kinds of animal ethics committees in order to clarify what is known about their operation and highlight information which is missing in their evaluation. Our main findings are that there is a significant variation in process...

  13. Sexuality and reproduction: implications in the process of healthy adolescence

    Directory of Open Access Journals (Sweden)

    Adelita Campos Araújo

    2012-06-01

    Full Text Available This study aimed to understand the perceptions of adolescents about their process of healthy adolescence with regard to sexuality and reproduction. This is a qualitative research of exploratory type, involving 10 teenagers, in a state school in southern Rio Grande do Sul, between August and October 2007. To collect the data, were used semi-structured interviews, whose contents were subjected to thematic analysis, emerging the theme: sexuality and reproduction in adolescence. At the data, it was noticed the need to provide more guidelines to a healthy adolescence, in the sense of strengthening and promoting the necessary security for the exercise of adolescent sexuality and reproduction. It also showed the need to prepare the adolescent by professionals of health, of education or the family, to face some situations, such as: unwanted pregnancy, first sexual intercourse, self-medication, fear of talking to parents about sexuality and reproduction, among others.

  14. Seroprevalence of infectious bovine rhinotracheitis in dairy animals with reproductive disorders in Uttar Pradesh, India.

    Science.gov (United States)

    Verma, Amit Kumar; Kumar, Amit; Sahzad; Reddy, N C Prakash; Shende, A N

    2014-05-01

    Respiratory and reproductive disorders in dairy animals due to various etiological agents have led to significant economic losses to dairy industry. These losses are due to abortions, metritis, retention of placenta, repeat breeding, death of animals, loss of production and trade restrictions etc. The objectives of this cross-sectional study were to detect the seroprevalence of infectious bovine rhinotracheitis (IBR, BHV-1) in dairy animals of western parts of Uttar Pradesh, India. Anti BHV-1 antibodies were measured using a commercial ELISA kit (SYANOVIR® IBR-Ab). Blood samples were collected from a total of 134 animals of different age, gender from 8 districts. Overall individual seroprevalence was 32.84%. The study revealed that BHV-1 is comparatively more widespread in cattle (46.51%) than buffalo (35.28%). Comparison of different sex groups of animals revealed that the higher numbers of infected animals were identified in male (48.00%) than female (29.35%). The seropositivity of IBR increased with age of animals. The highest prevalence of IBR (66.67%) was observed in animals aged more than 8 years. As vaccination against IBR is not practiced in the region and higher percent positivity (>20%) in all age group of animals indicated the natural circulation of BHV-1 virus in the population. Because of less awareness on the vaccination of animals against this virus, the disease may spread rapidly. The results of present study also indicate that strict monitoring and surveillance of IBR is need of today to protect the animals from infection and further spread. PMID:26031007

  15. Strengthening research on animal reproduction and disease diagnosis in Asia through the application of immunoassay techniques

    International Nuclear Information System (INIS)

    This publication contains the results presented by participants of a final Research Co-ordination Meeting which was held from 1 to 5 February 1993 at the University of Chulalongkorn, Bangkok, Thailand, as part of an FAO/IAEA Co-ordinated Research Programme on Strengthening Research on Animal Reproduction and Disease Diagnosis in Asia through the Application of Immunoassay Techniques. The purpose of this Programme was essentially to encourage national livestock production and veterinary institutes in Asia to conduct on-farm research into existing constraints on animal productivity and ways of reducing or removing these through low cost changes in management. Emphasis was given to defining existing levels of reproductive efficiency in indigeneous livestock and examining responses to nutritional or other interventions, and to exploring possibilities for using new approaches for diagnosing and controlling some diseases considered to impact adversely on Asian livestock production. Within the framework of all studies, immunoassay (radioimmunoassay and enzyme-linked immunosorbent assay) were employed for measuring levels of reproductive hormones or detecting antibodies to a variety of disease causing agents, the aim being to gain better insight into the underlying nature of the problems being encountered and reasons for the success or otherwise of approaches taken for their resolution. Refs, figs and tabs

  16. Banking crisis in the reproductive processes of the globalize economy

    OpenAIRE

    Reverchuk, S.; Kovalyuk, A.

    2009-01-01

    The meaning of banking sector in the economical system of the state is shown, the reasons of the banking crisis origin its features and classification are described and also the ways of banking crisis negotiation in the reproductive processes of the globalize economy are represented.

  17. Developmental and reproductive toxicity of inorganic arsenic: animal studies and human concerns.

    Science.gov (United States)

    Golub, M S; Macintosh, M S; Baumrind, N

    1998-01-01

    Information on the reproductive and developmental toxicity of inorganic arsenic is available primarily from studies in animals using arsenite and arsenate salts and arsenic trioxide. Inorganic arsenic has been extensively studied as a teratogen in animals. Data from animal studies demonstrate that arsenic can produce developmental toxicity, including malformation, death, and growth retardation, in four species (hamsters, mice, rats, rabbits). A characteristic pattern of malformations is produced, and the developmental toxicity effects are dependent on dose, route, and the day of gestation when exposure occurs. Studies with gavage and diet administration indicate that death and growth retardation are produced by oral arsenic exposure. Arsenic is readily transferred to the fetus and produces developmental toxicity in embryo culture. Animal studies have not identified an effect of arsenic on fertility in males or females. When females were dosed chronically for periods that included pregnancy, the primary effect of arsenic on reproduction was a dose-dependent increase in conceptus mortality and in postnatal growth retardation. Human data are limited to a few studies of populations exposed to arsenic from drinking water or from working at or living near smelters. Associations with spontaneous abortion and stillbirth have been reported in more than one of these studies, but interpretation of these studies is complicated because study populations were exposed to multiple chemicals. Thus, animal studies suggest that environmental arsenic exposures are primarily a risk to the developing fetus. In order to understand the implications for humans, attention must be given to comparative pharmacokinetics and metabolism, likely exposure scenarios, possible mechanisms of action, and the potential role of arsenic as an essential nutrient. PMID:9644328

  18. El bienestar animal en la reproducción y producción de cerdos - The animal welfare in the reproduction and production of pigs

    Directory of Open Access Journals (Sweden)

    Alejandro Córdova Izquierdo

    2007-12-01

    Full Text Available RESUMENEl bienestar animal es una condición ideal, resultado de la aplicación de normas específicas, adecuadas y posibles, sobre los sistemas y procesos involucrados a lo largo de toda la cadenaproductiva, que permiten a los animales vivir en las mejores condiciones posibles, sin padecer sufrimientos físicos o psicológicos innecesarios. Para todos los animales y en especial para aquellos cuyo destino será servir de fuente de alimentos al hombre, se antensifica el compromiso ético de brindarles a lo largo de su vida productiva las mejores condiciones posibles de hábitat, sanidad, manejo, alimentación y cuidados en general. En la actualidad,conceptos de bienestar animal, son cuestión de interés público complejo y multifacético que incluye importantes dimensiones científicas, éticas, económicas y políticas. Por ser un temade importancia creciente en la sociedad, el bienestar animal ha de abordarse sobre bases científicas verdaderas. Las causas de los problemas de bienestar animal, se deben a la percepción errónea acerca de los animales, como seres que no sienten y que por lo tanto, no son capaces de sufrir. Es fácil que se desarrollen actitudes negativas hacia los animales, lo cual se refleja en conductas de negligencia, crueldad o trato irrespetuoso. Los productores,médicos veterinarios, así como la sociedad en general, concientes del cuidado de los animales, saben la importancia de conocer los aspectos del confort de los animales ya que la fisiología, el desarrollo y el comportamiento del animal, son afectados por las malas condiciones ambientales, de producción y de manejo en general. En esta revisión, se presentan aspectos relacionados con el bienestar animal en la reproducción y producción de cerdos.ABSTRACTThe animal wefare is an ideal condition, result of the application of specific, appropriate and possible norms, on the systems and processes involved along the whole productive chain thatyou/they allow to the

  19. Animations to illustrate the Autocalibration process of accelerometer data

    OpenAIRE

    van Hees, Vincent ,

    2014-01-01

    .avi files: animation_a_6_3D_prepostautocal.avi ? 3D animation showing static points before and after autocalibration process. animation_c_4_2D_duringautocal.avi ? 2D animation showing how static points moved during autocalibration. animation_d_3_3D_duringautocal.avi ? 3D animation showing how static points moved during autocalibration.

  20. Funding priorities in animal reproduction at the United States Department of Agriculture's Cooperative State Research, Education, and Extension Service.

    Science.gov (United States)

    Mirando, Mark A; Hamernik, Debora L

    2006-03-01

    The National Research Initiative (NRI) Competitive Grants Program is the U.S. Department of Agriculture's major competitive grants program and is administered by the Cooperative State Research, Education, and Extension Service (CSREES). Since its inception in 1991, the NRI has funded competitive grants in the discipline of animal reproduction. Previously, this program provided funding for a broad range of projects encompassing almost every subdiscipline in reproductive biology of farm animals, including aquatic species important to the aquaculture industry. During fiscal year 2004, the NRI Animal Reproduction Program narrowed the focus of funding priorities to the topics of infertility, basic mechanisms regulating fertility, cryopreservation of gametes, reducing the postpartum interval to conception, and sterilization methods or development of monosex populations. In response to a directive to further narrow the focus of funding priorities for fiscal year 2005 and beyond, CSREES conducted a Stakeholder Workshop on Funding Priorities in Animal Reproduction at the 37th Annual Meeting of the Society for the Study of Reproduction in Vancouver, Canada. More than 75 stakeholder scientists from a cross section of federal, public, and private institutions from across the United States participated in the workshop and provided recommendations to CSREES for future NRI-funding priorities in Animal Reproduction. The recommendations provided by stakeholders included continuing efforts to focus funding priorities into fewer high-impact areas relevant to animal agriculture and aquaculture. Recommendations also included movement back toward subdisciplines of animal reproduction that cut across all applicable species. The three funding priorities that consistently emerged as recommendations from the workshop participants were 1) gonadal function and production of gametes, 2) pituitary-hypothalamic function, and 3) embryo and conceptus development, including interaction between the

  1. Endogenous Synthesis of Amino Acids Limits Growth, Lactation, and Reproduction in Animals.

    Science.gov (United States)

    Hou, Yongqing; Yao, Kang; Yin, Yulong; Wu, Guoyao

    2016-03-01

    Amino acids (AAs) are building blocks of protein. Eight AAs (Ala, Asn, Asp, Glu, Gln, Gly, Pro, and Ser) are formed by all animals, whereas de novo synthesis of Arg occurs in a species-specific manner in most mammals (e.g., humans, pigs, and rats). Synthesizable AAs were traditionally classified as nutritionally nonessential for animals, because they were thought to be formed in sufficient amounts. However, this assumption is not supported by evidence showing that 1) rats grow slowly when their diets do not contain Arg, Glu, or Gln despite adequate provision of all other proteinogenous AAs; 2) pigs cannot achieve maximum growth, lactation, or reproduction performance when fed corn- and soybean meal-based diets meeting National Research Council-recommended requirements of protein and AAs without supplemental Arg, Glu, Gln, Gly, or Pro; 3) chickens exhibit increases in lean tissue gain and feed efficiency when their diets are supplemented with Glu, Gln, Gly, and Pro; 4) lactating cows cannot obtain maximum milk protein production without a postruminal supply of Gln or Pro; 5) fish cannot achieve maximum growth when diets do not contain Gln or Pro; and 6) men fail to sustain spermatogenesis when fed an Arg-deficient diet. Quantitative analysis of nitrogen metabolism showed that AA synthesis in animals is constrained by both precursor availability and enzyme activity. Taken together, these findings support the conclusion that the endogenous synthesis of AAs limits growth, lactation, and reproduction in animals. This new knowledge can guide the optimization of human nutrition for improving health and well-being. PMID:26980816

  2. Novel approaches in andrology examination and follicular fluid biochemical characterization in the optimization of reproductive technologies in farm animals

    OpenAIRE

    Vencato, Juri

    2014-01-01

    The purpose of the studies reported in this Thesis was to increase our understanding of two aspects of the reproductive system in farm animals: the andrological evaluation and the follicular fluid composition. The final aim was to give some tools that can be helpful in optimizing the application of assisted reproductive technologies. Studies were conducted in bulls, rams, alpacas, lamas and dairy buffalo cows. The first study was designed to investigate the efficacy of scrotal thermograp...

  3. Review of reproductive and developmental toxicity induced by organotins in aquatic organisms and experimental animals

    Energy Technology Data Exchange (ETDEWEB)

    Hirose, A.; Takagi, A.; Nishimura, T.; Kanno, J.; Ema, M. [National Inst. of Health Sciences, Tokyo (Japan)

    2004-09-15

    Widespread use of organotins has caused increasing amounts to be released into the environment. The most important non-pesticidal route of entry of organotins into the environment is through leaching of organotin-stabilized PVC in water, and the use in antifouling agents, resulting in the introduction of organotin into the aquatic environment. Data are available regarding the detection of butyltins and phenyltins in aquatic marine organisms and marine products. Food chain bioamplification of butyltin in oysters, mud crabs, marine mussels, chinook salmons, dolphins, tunas, and sharks and of phenyltin in carps and horseshoe crabs has been reported. These findings indicate that organotins accumulate in the food chain and are bioconcentrated, and that humans can be exposed to organotins via seafood. The levels of organotin compounds in seafood are not considered to be sufficiently high to affect human health. However, Belfroid et al. (2000) noted that more research on residual TBT levels in seafood was needed before a definitive conclusion on possible health risks could be drawn. Although the toxicity of organotins has been extensively reviewed, the reproductive and developmental toxicity of organotins is not well understood. We summarized the data of the studies on reproductive and developmental toxicity of organotins in aquatic organisms and experimental animals.

  4. Coxiella burnetii associated reproductive disorders in domestic animals-a critical review

    Directory of Open Access Journals (Sweden)

    Agerholm Jørgen S

    2013-02-01

    Full Text Available Abstract The bacterium Coxiella burnetii has been detected in the fetal membranes, birth fluids and vaginal mucus, as well as in the milk and other excretions of several domestic mammals. The finding of C. burnetii in association with abortion, parturition and in the postpartum period has led to the hypothesis that C. burnetii causes a range of reproductive diseases. This review critically evaluates the scientific basis for this hypothesis in domestic mammals. The review demonstrates a solid evidence for the association between C. burnetii infection and sporadic cases of abortion, premature delivery, stillbirth and weak offspring in cattle, sheep and goats. C. burnetii induced in-herd epidemics of this complete expression of reproductive failure have been reported for sheep and goats, but not for cattle. The single entities occur only as part of the complex and not as single events such as generally increased stillbirth rate. Studies show that C. burnetii initially infects the placenta and that subsequent spread to the fetus may occur either haematogenous or by the amniotic-oral route. The consequences for the equine, porcine, canine and feline conceptus remains to the elucidated but that infection of the conceptus may occur is documented for most species. There is no solid evidence to support a hypothesis of C. burnetii causing disorders such as subfertility, endometritis/metritis, or retained fetal membranes in any kind of domestic animal species. There is a strong need to validate non-pathology based methods such as polymerase chain reaction for their use in diagnostic and research in relation to establishing C. burnetii as the cause of abortion and to adapt an appropriate study design and include adequate control animals when linking epidemiological findings to C. burnetii or when evaluating effects of vaccination in production herds.

  5. Coxiella burnetii associated reproductive disorders in domestic animals-a critical review

    Science.gov (United States)

    2013-01-01

    The bacterium Coxiella burnetii has been detected in the fetal membranes, birth fluids and vaginal mucus, as well as in the milk and other excretions of several domestic mammals. The finding of C. burnetii in association with abortion, parturition and in the postpartum period has led to the hypothesis that C. burnetii causes a range of reproductive diseases. This review critically evaluates the scientific basis for this hypothesis in domestic mammals. The review demonstrates a solid evidence for the association between C. burnetii infection and sporadic cases of abortion, premature delivery, stillbirth and weak offspring in cattle, sheep and goats. C. burnetii induced in-herd epidemics of this complete expression of reproductive failure have been reported for sheep and goats, but not for cattle. The single entities occur only as part of the complex and not as single events such as generally increased stillbirth rate. Studies show that C. burnetii initially infects the placenta and that subsequent spread to the fetus may occur either haematogenous or by the amniotic-oral route. The consequences for the equine, porcine, canine and feline conceptus remains to the elucidated but that infection of the conceptus may occur is documented for most species. There is no solid evidence to support a hypothesis of C. burnetii causing disorders such as subfertility, endometritis/metritis, or retained fetal membranes in any kind of domestic animal species. There is a strong need to validate non-pathology based methods such as polymerase chain reaction for their use in diagnostic and research in relation to establishing C. burnetii as the cause of abortion and to adapt an appropriate study design and include adequate control animals when linking epidemiological findings to C. burnetii or when evaluating effects of vaccination in production herds. PMID:23419216

  6. Coxiella burnetii associated reproductive disorders in domestic animals--a critical review.

    Science.gov (United States)

    Agerholm, Jørgen S

    2013-01-01

    The bacterium Coxiella burnetii has been detected in the fetal membranes, birth fluids and vaginal mucus, as well as in the milk and other excretions of several domestic mammals. The finding of C. burnetii in association with abortion, parturition and in the postpartum period has led to the hypothesis that C. burnetii causes a range of reproductive diseases. This review critically evaluates the scientific basis for this hypothesis in domestic mammals.The review demonstrates a solid evidence for the association between C. burnetii infection and sporadic cases of abortion, premature delivery, stillbirth and weak offspring in cattle, sheep and goats. C. burnetii induced in-herd epidemics of this complete expression of reproductive failure have been reported for sheep and goats, but not for cattle. The single entities occur only as part of the complex and not as single events such as generally increased stillbirth rate. Studies show that C. burnetii initially infects the placenta and that subsequent spread to the fetus may occur either haematogenous or by the amniotic-oral route. The consequences for the equine, porcine, canine and feline conceptus remains to the elucidated but that infection of the conceptus may occur is documented for most species. There is no solid evidence to support a hypothesis of C. burnetii causing disorders such as subfertility, endometritis/metritis, or retained fetal membranes in any kind of domestic animal species.There is a strong need to validate non-pathology based methods such as polymerase chain reaction for their use in diagnostic and research in relation to establishing C. burnetii as the cause of abortion and to adapt an appropriate study design and include adequate control animals when linking epidemiological findings to C. burnetii or when evaluating effects of vaccination in production herds. PMID:23419216

  7. Role of human- and animal-sperm studies in the evaluation of male reproductive hazards

    Energy Technology Data Exchange (ETDEWEB)

    Wyrobek, A.J.; Gordon, L.; Watchmaker, G.

    1982-04-07

    Human sperm tests provide a direct means of assessing chemically induced spermatogenic dysfunction in man. Available tests include sperm count, motility, morphology (seminal cytology), and Y-body analyses. Over 70 different human exposures have been monitored in various groups of exposed men. The majority of exposures studied showed a significant change from control in one or more sperm tests. When carefully controlled, the sperm morphology test is statistically the most sensitive of these human sperm tests. Several sperm tests have been developed in nonhuman mammals for the study of chemical spermatotoxins. The sperm morphology test in mice has been the most widely used. Results with this test seem to be related to germ-cell mutagenicity. In general, animal sperm tests should play an important role in the identification and assessment of potential human reproductive hazards. Exposure to spermatotoxins may lead to infertility, and more importantly, to heritable genetic damage. While there are considerable animal and human data suggesting that sperm tests may be used to detect agents causing infertility, the extent to which these tests detect heritable genetic damage remains unclear. (ERB)

  8. The National Research Initiative Competitive Grants Program in animal reproduction: changes in priorities and scope relevant to United States animal agriculture.

    Science.gov (United States)

    Mirando, M A

    2007-03-01

    The National Research Initiative (NRI) Competitive Grants Program is the USDA's major competitive grants program and is administered by the Cooperative State Research, Education, and Extension Service. The NRI was authorized by the US Congress in the 1990 Farm Bill at a funding level of $500 million; however, the maximal NRI appropriation was $181.17 million in fiscal year (FY) 2006. Across all programs, the NRI is mandated to use 40% of its funding to support mission-linked research. Since its inception in 1991, the NRI has funded competitive grants in the discipline of animal reproduction. Before 2004, the Animal Reproduction Program funded a broad range of projects encompassing almost every subdiscipline in reproductive biology of farm animals, including aquatic species important to the aquaculture industry and laboratory animals. During FY 2004, the NRI Animal Reproduction Program narrowed the focus of its funding priorities to 5 issue-based topics in an effort to make greater measurable improvements in a few high-impact areas over the next 10 years. Funding priorities were narrowed further in FY 2006 to 3 subdisciplines based, in part, on recommendations that emerged from a stakeholder workshop conducted by Cooperative State Research, Education, and Extension Service in August 2004. In FY 2003, Congress authorized expenditure of up to 20% of the funds appropriated to the NRI to support projects that integrate at least 2 of the 3 functions of research, education, and extension. In FY 2004, the Animal Reproduction Program included a funding priority for integrated projects focused primarily on infertility in dairy cattle. The program funded its first integrated project in FY 2005. During FY 2002, increased emphasis on justification for the use of model systems (e.g., laboratory animals and in vitro systems) was included in the NRI request for applications. In FY 2006, applications proposing to primarily utilize nonagricultural animal models were excluded from

  9. Animal models for information processing during sleep.

    Science.gov (United States)

    Coenen, A M L; Drinkenburg, W H I M

    2002-12-01

    Information provided by external stimuli does reach the brain during sleep, although the amount of information is reduced during sleep compared to wakefulness. The process controlling this reduction is called 'sensory' gating and evidence exists that the underlying neurophysiological processes take place in the thalamus. Furthermore, it is clear that stimuli given during sleep can alter the functional state of the brain. Two factors have been shown to play a crucial role in causing changes in the sleeping brain: the intensity and the relevance of the stimulus. Intensive stimuli arouse the brain, as well as stimuli having a high informational impact on the sleeping person. The arousal threshold for important stimuli is quite low compared to neutral stimuli. A central question in sleep research is whether associative learning, or in other words the formation of new associations between stimuli, can take place in a sleeping brain. It has been shown that simple forms of learning are still possible during sleep. In sleeping rats, it is proven that habituation, an active, simple form of learning not to respond to irrelevant stimuli, can occur. Moreover, there is evidence for the view that more complex associations can be modulated and newly formed during sleep. This is shown by two experimental approaches: an extinction paradigm and a latent inhibition (pre-exposure) paradigm. The presentation of non-reinforced stimuli during sleep causes slower extinction compared to the same presentation of these stimuli during wakefulness. Consistently, the suppressive capacity of a stimulus in the latent inhibition paradigm is less when previously pre-exposed during sleep, as compared to pre-exposure during wakefulness. Thus, while associative learning is not completely blocked during sleep, aspects of association formation are clearly altered. However, animal studies also clearly indicate that complex forms of learning are not possible during sleep. It is hypothesised that this

  10. Humans act against the natural process of breeder selection: A modern sickness for animal populations?

    OpenAIRE

    Balbontín, Javier; Penteriani, Vincenzo; Ferrer, Miguel, ed.imp.lib

    2005-01-01

    We present a new idea about the possible effects of human-induced mortality on different age cohorts (i.e., breeders vs. juveniles) in long-lived animals. Our hypothesis is based on Curio's idea on the effect of natural selective processes on cohorts to explain age-related increases in fecundity (selection hypothesis). We believe that negative human pressure may modify such contribution to reproduction of good versus low quality phenotypes, altering the genetic structure of the population. Ec...

  11. Proteomics of boar seminal plasma - current studies and possibility of their application in biotechnology of animal reproduction.

    Science.gov (United States)

    Strzeżek, Jerzy; Wysocki, Paweł; Kordan, Władysław; Kuklińska, Magdalena; Mogielnicka, Marzena; Soliwoda, Daniel; Fraser, Leyland

    2005-11-01

    Proteomics is critical to identify the properties and functions of proteins involved in the mechanism regulating the male reproductive tract function. This approach is important in male fertility assessment and clinical diagnosis of the physiological state of individual reproductive organs. Proteomics also provides a tool to understand the interactions of seminal plasma proteins with spermatozoa, which could provide a useful model for studying ligand-cell interaction occurring at the sperm cell surface. This review covers a selection of advances in the realm of functional proteomics of boar seminal plasma proteins and is focused on some fundamental proteomic technologies. Also, this review explores key themes in proteomics and their application in animal reproductive techniques. PMID:16372045

  12. The endocrine system controlling sexual reproduction in animals: Part of the evolutionary ancient but well conserved immune system?

    Science.gov (United States)

    De Loof, Arnold; Schoofs, Liliane; Huybrechts, Roger

    2016-01-15

    Drastic changes in hormone titers, in particular of steroid hormones, are intuitively interpreted as necessary and beneficial for optimal functioning of animals. Peaks in progesterone- and estradiol titers that accompany the estrus cycle in female vertebrates as well as in ecdysteroids at each molt and during metamorphosis of holometabolous insects are prominent examples. A recent analysis of insect metamorphosis yielded the view that, in general, a sharp rise in sex steroid hormone titer signals that somewhere in the body some tissue(s) is undergoing programmed cell death/apoptosis. Increased steroid production is part of this process. Typical examples are ovarian follicle cells in female vertebrates and invertebrates and the prothoracic gland cells, the main production site of ecdysteroids in larval insects. A duality emerges: programmed cell death-apoptosis is deleterious at the cellular level, but it may yield beneficial effects at the organismal level. Reconciling both opposites requires reevaluating the probable evolutionary origin and role of peptidic brain hormones that direct steroid hormone synthesis. Do e.g. Luteinizing Hormone in vertebrates and Prothoracicotropic Hormone (PTTH: acting through the Torso receptor) in insects still retain an ancient role as toxins in the early immune system? Does the functional link of some neuropeptides with Ca(2+)-induced apoptosis make sense in endocrine archeology? The endocrine system as a remnant of the ancient immune system is undoubtedly counterintuitive. Yet, we will argue that such paradigm enables the logical framing of many aspects, the endocrine one inclusive of both male and female reproductive physiology. PMID:26707056

  13. The zebrafish: an emerging animal model for investigating the hypothalamic regulation of reproduction.

    Science.gov (United States)

    Bassi, Ivan; ANDRé, Valentina; Marelli, Federica; Vezzoli, Valeria; Merlo, Giorgio R; Cariboni, Anna; Persani, Luca; Gothilf, Yoav; Bonomi, Marco

    2016-06-01

    Gonadotropin-releasing hormone (GnRH) neurons have a pivotal role in the physiological functions of hypotahlamic-pituitary-gonadal (HPG) axis. The pulsatile releasing of GnRH hormone into the hypophyseal portal circulation at the median eminence represent the first domino in the HPG cascade of events that regulate the development, fertility and aging in all vertebrates. These neurons principally originate in the olfactory placode and migrate during early embryonal stages into the hypothalamus. Alterations in developmental processes or in the releasing of GnRH hormone lead to a rare and complex disorder of the reproductive axis called congenital hypogonadotropic hypogonadism (CHH). Genetic screening of human patients and the use of model systems have led to the identification of several genes involved in the CHH pathogenesis underlying its oligogenic nature. Nevertheless CHH remains, for a large cohort of patients, idiopathic and GnRH neurogenesis processes not fully understood. This is due to intrinsic difficulties that exist in the analysis of earliest embryonic developmental stages and in the methodologies developed to study the CHH-causing genes. In this regard, zebrafish embryos, on account of its external fertilization and development, allow a real-time analysis that could overcome some of the above mentioned limitations. Moreover, the recent availability of several transgenic zebrafish reporter lines makes it an excellent model for the study of the oligogenic mechanisms leading to CHH. PMID:26934719

  14. Animal models for information processing during sleep

    NARCIS (Netherlands)

    Coenen, A.M.L.; Drinkenburg, W.H.I.M.

    2002-01-01

    Information provided by external stimuli does reach the brain during sleep, although the amount of information is reduced during sleep compared to wakefulness. The process controlling this reduction is called `sensory' gating and evidence exists that the underlying neurophysiological processes take

  15. Archiving the animation film-making process. The earliest Dutch animation films

    NARCIS (Netherlands)

    Peters, Mette

    2012-01-01

    abstractAnimation film-makers working in the Netherlands in the first decade of the 20th century,made use of processes and skills from live-action film production and the world of the visualarts. And yet for the majority, making animation films was nothing more than an excursionduring their careers

  16. 30 CFR 250.196 - Reimbursements for reproduction and processing costs.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Reimbursements for reproduction and processing costs. 250.196 Section 250.196 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Reporting Requirements § 250.196 Reimbursements for reproduction and processing costs. (a) MMS...

  17. Production and processing of foodstuffs of animal origin in Morocco

    International Nuclear Information System (INIS)

    This paper reports the situation of the animal productions in Morocco. The author concludes that foodstuffs of animal origin are especially eaten fresh, the level of this consumption is low and the problems related to the food processing and distribution are somewhat elementary: that is particularly question of problems of hygiene, of wholesomeness and of organisation. (F.M.)

  18. TRIENNIAL REPRODUCTION SYMPOSIUM: American Society of Animal Science L. E. Casida Award for Excellence in Graduate Education: Thoughts on mentoring graduate students in reproductive biology.

    Science.gov (United States)

    Smith, M F

    2016-07-01

    Programs in animal science are particularly well suited for graduate education because students can receive comprehensive training in the laboratory as well as with the whole animal. Furthermore, graduate students in animal science have the opportunity to understand how their research relates to a real world problem. Graduate students need to take ownership of their education by identifying training goals, choosing a mentor who will help them achieve their goals, and becoming engaged in research as soon as possible. In my own graduate program, I emphasize concepts more than techniques and I believe that graduate course work should focus on the basic areas of science that underlie reproductive biology (e.g., endocrinology, biochemistry, physiology, immunology, and statistics). Based on the increase in technology available for scientific investigation and the diversity of expertise required to address important research problems, graduate students need to learn the importance of establishing productive collaborations and begin building a scientific network. Preparation for graduate school frequently begins early with a curiosity and passion for understanding how biology works. Undergraduate courses can facilitate scientific thinking by providing opportunities in lectures and laboratories for students to transition from passive learners to thinking of themselves as animal scientists. There is a profound difference between individuals who view themselves as practitioners of a discipline and those who are simply trying to complete a course requirement. Teachers of undergraduate courses should incorporate experiential learning exercises into their lectures and laboratories to provide undergraduate students the opportunity to function as animal scientists and to embrace their scientific education. Graduate training has been the most enjoyable aspect of my career and it has been a joy to witness the achievements of students following completion of their degree! PMID

  19. SHORT, MEDIUM AND LONG-TERM OPPORTUNITIES AND NEEDS FOR RESEARCH FOR SUSTAINABLE FARM ANIMAL BREEDING AND REPRODUCTION TECHNOLOGY IN EU

    Directory of Open Access Journals (Sweden)

    D. Kompan

    2007-06-01

    Full Text Available The European landscape is characterised by a range of diverse farming systems. These relate not only to varied geographical environments, but also to different social and cultural environments for farming and food production. This diversity is unique to Europe and underlines the importance of European agriculture. Animal breeding is a knowledge intensive sector, and for the future competitiveness of animal breeding and animal production, high level European research is indispensable. The preparation of Strategic Research Agenda were in a full process: opportunities and problems, gaps, short, medium and long term opportunities and needs for research. Each country experts from different group have opportunity to help define his country dimension of animal breeding in its regional and country context, and also in relation to European and global developments. The Farm Animal Breeding and Reproduction European Technology Platform, brings together a wide range of interested parties to produce a vision of how livestock breeding might develop in the next 20 years, and constitutes the first step in achieving that vision.

  20. The zootechnical applications of biotechnology in animal reproduction: current methods and perspectives

    OpenAIRE

    Thibier, Michel

    2005-01-01

    International audience The development of the four generations of Reproductive Biotechnology, particularly in cattle and since the last world war, represents one of the best examples of the success story of technology transfer. This review will only refer to the first three generations and will not deal with nuclear transfer nor transgenesis. Based on sound so-called "finalised" research, Artificial Insemination first, then in vivo collected embryo transfer and later in vitro fertilised em...

  1. Application of progesterone and testosterone in the diagnose and control of reproduction in crossbreds animal husbandry

    International Nuclear Information System (INIS)

    The progesterone (P4) dosage resource, by means of radioinmunologic techniques (RIA), allows to relate the variations of its concentration in peripheral blood or milk, in different ovarian function moments, identifying and controlling reproductive problems. In mixed breeds livestock rearing the P4 has been good to identify: 1) dynamics of normal oestrus cycles, frequency of anovulatory oestrus, silent and short cycles; 2) reproductive state of cows in herd (94% of success in gestation identification, anoestrus or cyclicity); 3) Mating moment, highlighting an error of 19-23% in the oestrus observations and its reduction up to 6-11% applying management measures; 13,7% of repeating cows were inseminated with high P4; 4) State of nopregnacy (95% of accuracy); 5) Beginning of puberty (628 d and 309 k), the anovulatory no puberal oestrus (8,2%) and the short cycles (16,5%), and its relationship with the Reproductive Tract Qualification (RTQ), Corporal Condition (CC) and with the nutritional improvement; 6) Cyclicity Restart post delivery, highlighting the dissociation oestrus-ovulation when characterizing the luteal activity at the beginning of post delivery (63% of short FL); 7) Different profiles of repeating cows cycle (10 categories); 8) Frequency of embryonic mortality with variations of 6,6-11 and 8-23%; 9) Diagnose of ovarian problems, especially the presence of cysts; 10) higher fertility (62%) observed with levels of 3 or more than 3 ng/ml of P4, 4-5 d before the mating; and 11) Its integration in the strategy for the management of Reproductive Control Programs and monitoring of synchronization of oestrus treatments. In mixed breeds young bulls, the seric levels of testosterone (1,6-1,9 ng/ml) point out puberty

  2. Coxiella burnetii associated reproductive disorders in domestic animals-a critical review

    OpenAIRE

    Agerholm Jørgen S

    2013-01-01

    Abstract The bacterium Coxiella burnetii has been detected in the fetal membranes, birth fluids and vaginal mucus, as well as in the milk and other excretions of several domestic mammals. The finding of C. burnetii in association with abortion, parturition and in the postpartum period has led to the hypothesis that C. burnetii causes a range of reproductive diseases. This review critically evaluates the scientific basis for this hypothesis in domestic mammals. The review demonstrates a solid ...

  3. Inter-observer agreement on a checklist to evaluate scientific publications in the field of animal reproduction.

    Science.gov (United States)

    Simoneit, Céline; Heuwieser, Wolfgang; Arlt, Sebastian P

    2012-01-01

    This study's objective was to determine respondents' inter-observer agreement on a detailed checklist to evaluate three exemplars (one case report, one randomized controlled study without blinding, and one blinded, randomized controlled study) of the scientific literature in the field of bovine reproduction. Fourteen international scientists in the field of animal reproduction were provided with the three articles, three copies of the checklist, and a supplementary explanation. Overall, 13 responded to more than 90% of the items. Overall repeatability between respondents using Fleiss's κ was 0.35 (fair agreement). Combining the "strongly agree" and "agree" responses and the "strongly disagree" and "disagree" responses increased κ to 0.49 (moderate agreement). Evaluation of information given in the three articles on housing of the animals (35% identical answers) and preconditions or pretreatments (42%) varied widely. Even though the overall repeatability was fair, repeatability concerning the important categories was high (e.g., level of agreement=98%). Our data show that the checklist is a reasonable and practical supporting tool to assess the quality of publications. Therefore, it may be used in teaching and practicing evidence-based veterinary medicine. It can support training in systematic and critical appraisal of information and in clinical decision making. PMID:22709736

  4. Animal experimentation in Malta : regulatory processes and future perspectives

    OpenAIRE

    Scerri, Charles

    2009-01-01

    Prior to Malta’s accession to the European Union (EU) in May 2004, new legislative processes regulating the use of animals for scientific research purposes were adopted in line with the provisions found under the European Union Council Directive 86/609/EEC. The scope of these regulations is to protect animals used or intended to be used in scientific experimental procedures which may cause pain, suffering, distress or lasting harm, using evaluation procedures that promote refinement, reductio...

  5. a New Animation of Subduction Processes for Undergraduates

    Science.gov (United States)

    Stern, R. J.; Lieu, W. K.; Mantey, A.; Ward, A.; Todd, F.; Farrar, E.; Sean, M.; Windler, J.

    2015-12-01

    The subduction of oceanic lithosphere beneath convergent plate margins is a fundamental plate tectonic concept and an important Earth process. It is responsible for some of Earth's most dangerous natural hazards including earthquakes and volcanic eruptions but also produced the continental crust and important mineral deposits. A range of geoscientific efforts including NSF MARGINS and GeoPRISMS initiatives have advanced our understanding of subduction zone processes. In spite the importance of subduction zones and our advancing understanding of how these function, there are few animations that clearly explain the subduction process to non-expert audiences. This deficiency reflects the disparate expertises between geoscientists who know the science but have weak animation skills and digital artists and animators who have strong skills in showing objects in motion but are not experts in natural processes like plate tectonics. This transdisciplinary gap can and should be bridged. With a small grant from NSF (DUE-1444954) we set about to generate a realistic subduction zone animation aimed at the university undergraduate audience by first working within our university to rough out a draft animation and then contract a professional to use this to construct the final version. UTD Geosciences faculty (Stern) and graduate student (Lieu) teamed up with faculty from UTD School of Arts, Technology, and Emerging Communication (ATEC)(Farrar, Fechter, and McComber) to identify and recruit talented ATEC undergraduate students (Mantey, Ward) to work on the project. Geoscientists assembled a storyboard and met weekly with ATEC undergraduates to generate a first draft of the animation, which guided development of an accompanying narrative. The draft animation with voice-over was then handed off to professional animator Windler (Archistration CG) to generate the final animation. We plan to show both the student-generated draft version and the final animation during our presentation

  6. Sperm processing for advanced reproductive technologies: Where are we today?

    Science.gov (United States)

    Rappa, Kari L; Rodriguez, Harold F; Hakkarainen, Gloria C; Anchan, Raymond M; Mutter, George L; Asghar, Waseem

    2016-01-01

    Assisted reproductive technologies (ARTs) utilize sperm sorting methods to select viable sperm from the semen samples. Conventional sperm sorting techniques in current use are density gradient centrifugation, direct swim-up, and conventional swim-up. These methods use multiple centrifugation steps, which have been shown to generate reactive oxygen species (ROS) that decrease DNA integrity and damage sperm. Newer technologies, such as microfluidics, electrophoresis, motile sperm organelle morphology examination (MSOME), and birefringence eliminate the centrifugation steps and can improve the selection of sperm with higher DNA integrity, normal morphology, and motility as well as improved artificial insemination outcomes. In this review, we discuss some recent research in centrifugation and non-centrifugation based techniques and their effect on sperm quality and ART outcomes. PMID:26845061

  7. From generalized directed animals to the asymmetric simple exclusion process

    International Nuclear Information System (INIS)

    Using the generalized normally ordered form of words in a locally-free group of n generators, we show that in the limit n → ∞, the partition function of weighted directed lattice animals on a semi-infinite strip coincides with the partition function of stationary configurations of the asymmetric simple exclusion process (ASEP) with arbitrary entry/escape rates through open boundaries. We relate the features of the ASEP in the different regimes of the phase diagram to the geometric features of the associated generalized directed animals by showing the results of numerical simulations. In particular, we show how the presence of shocks at the first order transition line translates into the directed animal picture. Using the evolution equation for generalized, weighted Lukasiewicz paths, we also provide a straightforward calculation of the known ASEP generating function. (paper)

  8. From generalized directed animals to the asymmetric simple exclusion process

    Science.gov (United States)

    Haug, N.; Nechaev, S.; Tamm, M.

    2014-10-01

    Using the generalized normally ordered form of words in a locally-free group of n generators, we show that in the limit n → ∞, the partition function of weighted directed lattice animals on a semi-infinite strip coincides with the partition function of stationary configurations of the asymmetric simple exclusion process (ASEP) with arbitrary entry/escape rates through open boundaries. We relate the features of the ASEP in the different regimes of the phase diagram to the geometric features of the associated generalized directed animals by showing the results of numerical simulations. In particular, we show how the presence of shocks at the first order transition line translates into the directed animal picture. Using the evolution equation for generalized, weighted Lukasiewicz paths, we also provide a straightforward calculation of the known ASEP generating function.

  9. Evaluation of a Commercial ELISA for Detection of Ruminant Processed Animal Proteins in Non-Ruminant Processed Animal Proteins

    NARCIS (Netherlands)

    Bremer, M.G.E.G.; Margry, R.J.C.F.; Vaessen, J.C.H.; Doremalen, van A.M.H.; Palen, van der J.G.P.; Kaathoven, van R.G.C.; Kemmers-Voncken, A.E.M.; Raamsdonk, van L.W.D.

    2013-01-01

    Due to a growing aquaculture industry, demand for high-quality proteins for aquatic feeds is increasing. Non-ruminant processed animal proteins (PAPs) have shown great potential for this purpose. Safe reintroduction of non-ruminant PAPs in aqua feed requires methods that can discriminate ruminant an

  10. The zootechnical applications of biotechnology in animal reproduction: current methods and perspectives.

    Science.gov (United States)

    Thibier, Michel

    2005-01-01

    The development of the four generations of Reproductive Biotechnology, particularly in cattle and since the last world war, represents one of the best examples of the success story of technology transfer. This review will only refer to the first three generations and will not deal with nuclear transfer nor transgenesis. Based on sound so-called "finalised" research, Artificial Insemination first, then in vivo collected embryo transfer and later in vitro fertilised embryo transfer have been implemented worldwide. Each of these Biotechnologies has many advantages and limitations. In addition to the specificity of each of them, one major point is that farmers and breeders may choose either collectively or individually, the best technology to be used in order to achieve the goals they have set for their industry. It is noteworthy that these technologies have been able to match with the economics demands over the last decades and yet are in a very good capacity to respond to the contemporary demand of sustainable development. In this context, there are further advantages such as potentially contributing to maintaining biodiversity or allowing preservation ex situ of genes otherwise threatened to extinction. PMID:15982450

  11. Radioimmunoassay determination of the effect on animal reproduction of alternative of feeding suplementation in dairy cows

    International Nuclear Information System (INIS)

    The principal object of this trial was to evaluate the influence of three alternatives of feeding suplementation in dairy cows in the post-partum period in ecuadorian highlands. Thirty sic animals in fist lactation were used in this experiment and were divided in three groups according to the feed intake: Group A diet was 5 Kg. of a commercial concentrate mixture with 12 per cent of crude protein plus pasture ad libitum; Group B diet was green banans (Musa paradisiaca) and pasture and Group C diet was the control only pasture. Using Radioimmunoassay technique (RIA), progesterone values were determinated in milk from each cow. the sampling was sequential, two samples a week, starting 6 days after parturition, until the animal was pregnant or until the study was finished, 150 days after post-partum for each cow. This research allowed us to evaluate the ovaric post-partum activity of each group: Frequency and length of the oestrus cycles; efficiency of oestrus detection, calving-first, oestrus period, calving-conception length, conception rate, and services per conception. Additional datas were used in this study such as: milk production, palpations and treatments

  12. Reproduction of superior sagittal sinus animal model by bypass transplantation of biomaterial graft

    Directory of Open Access Journals (Sweden)

    Qing-yong LUO

    2011-03-01

    Full Text Available Objective To establish the beagles model of superior sagittal sinus bypass graft,and explore the feasibility of reconstruction of superior sagittal sinus with biomaterials using this model.Methods Eight adult male beagles(weight: 12.5-22.0kg were involved in the present study.The superior sagittal sinus was exposed and blocked via bone window,and then anastomosed side-to-end to the biomaterial graft under the dedicated microscope of neurosurgery surgery,expectant treatment such as anti-inflammatory was given for the animals.The digital subtraction venography(DSV and color Doppler flow imaging(CDFI of superior sagittal sinus were performed in 1,2,4 and 8 weeks after the operation.Eight weeks after the operation,all the animals were sacrificed and the material graft was examined histologically.Results The DSV and CDFI of superior sagittal sinus showed that the stomas of 2 beagles were with slight stenosis and high flow velocity,of 1 beagle with small leakage and low flow velocity,while of other 5 beagles were normal.The histological examination showed endothelial cells were growing on the graft and superior sagittal sinus,and crawling toward the lumen of graft 8 weeks after the operation.Conclusion The beagles model of superior sagittal sinus bypass graft was established successfully.The short-term effect of the model was satisfactory,while further work should be performed to determine the long-term effects.

  13. From generalized directed animals to the asymmetric simple exclusion process

    OpenAIRE

    Haug, Nils; Nechaev, Sergei; Tamm, Mikhail

    2012-01-01

    Using the generalized normally ordered form of words in a locally-free group of $n$ generators, we show that in the limit $n\\to\\infty$, the partition function of weighted directed lattice animals on a semi-infinite strip coincides with the partition function of stationary configurations of the asymmetric simple exclusion process (ASEP) with arbitrary entry/escape rates through open boundaries. We relate the features of the ASEP in the different regimes of the phase diagram to the geometric fe...

  14. Processes of Middle-Class Reproduction in a Graduate Employment Scheme

    Science.gov (United States)

    Smart, Sarah; Hutchings, Merryn; Maylor, Uvanney; Mendick, Heather; Menter, Ian

    2009-01-01

    Teach First is an educational charity that places graduates to teach in "challenging" schools for two years. It is marketed as an opportunity to develop employability while "making a difference". In this paper, I examine the process of class reproduction occurring in this graduate employment scheme through examining the discourses used in Teach…

  15. Extraterrestrials and Generic Social Processes: Minimizing Resistance in Teaching the Reproduction of Inequality

    Science.gov (United States)

    Parrotta, Kylie L.; Rusche, Sarah Nell

    2011-01-01

    In this article, the authors describe a class activity that uses a combination of strategies to overcome obstacles students face when learning about the reproduction of inequality in everyday life. Based on Schwalbe et al.'s (2000) piece on "generic social processes," and following the idea of "making the strange familiar and the familiar…

  16. Symmetry breaking and coarsening in spatially distributed evolutionary processes including sexual reproduction and disruptive selection

    CERN Document Server

    Sayama, H; Bar-Yam, Y; Sayama, Hiroki; Kaufman, Les; Bar-Yam, Yaneer

    2000-01-01

    Sexual reproduction presents significant challenges to formal treatment of evolutionary processes. A starting point for systematic treatments of ecological and evolutionary phenomena has been provided by the gene centered view of evolution. The gene centered view can be formalized as a dynamic mean field approximation applied to genes in reproduction / selection dynamics. We show that spatial distributions of organisms with local mating neighborhoods in the presence of disruptive selection give rise to symmetry breaking and spontaneous pattern formation in the genetic composition of local populations. Global dynamics follows conventional coarsening of systems with nonconserved order parameters. The results have significant implications for ecology of genetic diversity and species formation.

  17. Animals

    International Nuclear Information System (INIS)

    The radionuclides of most concern with respect to contamination of animals after a nuclear accident are radioiodine, radiocaesium and radiostrontium (ICRP 30, 1979). Of the other significant anthropogenic radionuclides likely to be released in most accidents, only small proportions of that ingested will be absorbed in an animals gut, and the main animal products, milk and meat, will not normally be contaminated to a significant extent. Animal products will mostly be contaminated as a result of ingestion of contaminated feed and possibly, but to a much lesser extent, from inhalation (for radioiodine only). Direct external contamination of animals is of little or no consequence in human food production. Radioiodine and radiostrontium are important with respect to contamination of milk; radiocaesium contaminates both milk and meat. The physical and chemical form of a radionuclide can influence its absorption in the animal gut. For example, following the Chernobyl accident radiocaesium incorporated into vegetation by root uptake was more readily absorbed than that associated with the original deposit. The transfer of radiocaesium and radiostrontium to animals will be presented both as transfer coefficients and aggregated transfer coefficients. For most animal meat products, only radiocaesium is important as other radionuclides do not significantly contaminate muscle. Farm animal products are the most important foodstuff determining radiocaesium intake by the average consumer in the Nordic countries. The major potential source of radioiodine and radiostrontium to humans is milk and milk products. Of the different species, the smaller animals have the highest transfer of radiocaesium from fodder to meat and milk. (EG)

  18. The process of decision making in reproductive medicine.

    Science.gov (United States)

    Ludwig, Annika K; Diedrich, Klaus; Ludwig, Michael

    2005-11-01

    The decision-making process regarding the optimal infertility treatment strategy is influenced by several factors. In addition to the underlying cause of infertility, the process of decision making is also influenced by other factors. These factors are mainly (1) the duration of infertility, (2) patient's age, and (3) the number of previously performed treatment cycles of intrauterine insemination (IUI) or in vitro fertilization (IVF). The duration of infertility influences diagnostic steps as well as therapeutic options. With an infertility of at least 5 years the benefit of intrauterine insemination is limited and couples should be counseled to go forward with IVF. Patients age >or= 40 years should be treated with IVF, whereas patients age >or= 43 years should be counseled about their very limited chance to conceive even through IVF. The number of insemination cycles should be limited to four. Couples who have undergone at least six IVF cycles should be counseled to discontinue therapy. The treatment program should be as individualized as possible, with individual counseling that is adapted after each single treatment cycle. PMID:16317623

  19. Co-ordinated research programme on strengthening research on animal reproduction and disease diagnosis in Asia through the application of immunoassay techniques

    International Nuclear Information System (INIS)

    The activities of the Animal Production and Health Section of the Joint FAO/IAEA Division are carried out through the operation of Co-ordinated Research Programmes and Technical Co-operation projects, both of which aim to encourage and improve the capacity of national institutions in tropical and subtropical countries to identify and resolve problems connected with livestock development. This particular programme was initiated in 1987 using funds made available from the IAEA's Regular Budget. At the outset, it was envisaged that an inter-disciplinary approach would be adopted by each participating institute whereby studies on nutrition, reproduction and health would be integrated into a number of site specific projects. From the project proposals received for evaluation, however, it was clear that the Programme would best be implemented by running two ''sub-programmes''. One to cover animal production and focussing on animal reproduction and reproduction-nutrition interactions; and the second to deal with animal disease control through development of better diagnostic methods and studies on epidemiology. This paper contains an outline of nuclear and related techniques used during this study. 1 ref

  20. Effects of different animal manures on attraction and reproductive behaviors of common house fly, Musca domestica L.

    Science.gov (United States)

    Shah, Rizwan Mustafa; Azhar, Faheem; Shad, Sarfraz Ali; Walker, William B; Azeem, Muhammad; Binyameen, Muhammad

    2016-09-01

    Insects rely mainly on their well-developed and highly sophisticated olfactory system to discriminate volatile cues released from host and nonhost substances, mates, oviposition substrates, and food sources. Onset of first mating, mating duration, and onset of first oviposition, oviposition period, fecundity (number of eggs laid by a female), and longevity of freshly emerged Musca domestica L. (Diptera: Muscidae) adults were observed in the presence of different animal manures: cow, horse, donkey, poultry, and an artificial diet. The M. domestica adults exposed to horse manure showed a delay in onset of first mating and first oviposition, prolonged mating duration, and reduced fecundity compared to the artificial diet (control). Likewise, the fecundity was reduced in the presence of donkey manure as compared to artificial diet. The onset of first mating was delayed and duration of first mating was shortened in the presence of cow manure as compared to artificial diet and no oviposition was observed throughout the duration of the experiment. However, the reproductive behaviors and all fitness measures in adults exposed to poultry manure were similar or even better, compared to the artificial diet. Surprisingly, in a free-choice attraction assay, the highest numbers of adult flies were attracted toward the cow manure as compared to all other manures as well as the artificial diet. However, the numbers of flies captured in all other types of manures were not different than the artificial diet (control). Furthermore, chemical analysis of headspace samples of manures revealed qualitative differences in odor (volatile) profiles of all manures and artificial diet, indicating that behavioral differences could be due to the differences in the volatile chemistry of the adult ovipositional substrates and larval growth mediums. This study may contribute toward both understanding the linkage between ecological adaptations and host selection mechanisms and the development of

  1. Impact of the Phytoestrogen Content of Laboratory Animal Feed on the Gene Expression Profile of the Reproductive System in the Immature Female Rat

    OpenAIRE

    Naciff, Jorge M; Overmann, Gary J.; Torontali, Suzanne M.; Carr, Gregory J.; Tiesman, Jay P.; DASTON, GEORGE P.

    2004-01-01

    The effect of the dietary background of phytoestrogens on the outcome of rodent bioassays used to identify and assess the reproductive hazard of endocrine-disrupting chemicals is controversial. Phytoestrogens, including genistein, daidzein, and coumestrol, are fairly abundant in soybeans and alfalfa, common ingredients of laboratory animal diets. These compounds are weak agonists for the estrogen receptor (ER) and, when administered at sufficient doses, elicit an estrogenic response in vivo. ...

  2. Control tools to detect processed animal proteins in feed and in animal by-products: specificity and challenges

    Directory of Open Access Journals (Sweden)

    Woodgate SL.

    2009-01-01

    Full Text Available AbstractThis paper reviews the current situation with regard to a total feed ban on the use of processed animal proteins in feed for meat producing animals within the EU. The scientific aspects surrounding the development of control tools are discussed. In particular, focus is given to methods for marking those materials prohibited in animal feeds and for the determination of species specificity in those proteins that are potentially allowed in animal feeds. The overall objective is that the advancements in science are utilized to achieve a partial relaxation of the total feed ban in the near future.

  3. Process of couple communication in reproductive health among rural married couples in India

    OpenAIRE

    Santosh Karvande, Shilpa

    2009-01-01

    Communication is often recognized as a cornerstone of modern society. Helping couples communicate about reproductive health is viewed as vital for involvement of both the partners in decision making, treatment seeking and promoting health. It is hence crucial to understand ‘communication’ among married partners before designing any couple-targeted strategies. Communication is a process which involves more than sending and receiving messages. For comprehensive understanding of communication, i...

  4. Animals

    Institute of Scientific and Technical Information of China (English)

    杨光

    2000-01-01

    The largest animal ever to live on the earth is the blue whale(蓝鲸)It weighs about 80 tons--more than 24 elephants. It is more than 30 metres long. A newborn baby whale weighs as much as a big elephant.

  5. Application of hydrolyzed proteins of animal origin in processed meat.

    Science.gov (United States)

    Meinert, Lene; Broge, Eva Honnens de Lichtenberg; Bejerholm, Camilla; Jensen, Kirsten

    2016-03-01

    With increasing consumer interest in functional foods, proteins from slaughterhouse side streams can offer interesting application opportunities in this respect. Worldwide, increasing numbers of people are suffering from hypertension and protein deficiency. Hydrolyzed proteins of animal origin may show ACE-inhibitory activity, which is central to the treatment of hypertension. Furthermore, the protein content of, for example, meat products increases markedly through the addition of hydrolyzed proteins, and these protein-rich products are of interest to those suffering from protein deficiency. Through a series of analyses, six selected hydrolysates were analyzed for their application potential in the Danish meat product saveloy. Hydrolyzed pig rectum and bovine diaphragm showed the highest ACE-inhibitory activities, and these activities were maintained in the processed saveloys. The ACE-inhibitory activities could not readily be explained by the amino acid profile. The content of N-compounds in the saveloys increased with increasing addition of hydrolysate, with little difference between the added hydrolysates. A sensory panel assessed the saveloys with added porcine rectum (8%), bovine diaphragm (8%), and bovine heart (4% and 8%) as having the strongest off-flavors (chemical flavor). No increase in salty taste resulting from the addition of hydrolysates was detected in the saveloys. Finally, the consumers found the saveloys too mild in flavor and recommended the addition of more spices. PMID:27004118

  6. ANIMALS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Mammals(哺乳动物)Mammals are the world's most dominant(最占优势的)animal.They are extremely(非常)diverse(多种多样的)creatures(生物,动物)that include(包括)the biggest ever animal (the blue whale鲸,which eats up to 6 tons every day),the smallest(leaf-nosed bat小蹄蝠) and the laziest(sloth树獭,who spends 80% of their time sleeping).There are over 4,600 kinds of mammals and they live in very different environments(环境)—oceans(海洋),rivers,the jungle(丛林),deserts,and plains(平原).

  7. Reproductive technologies and reproductive rights

    OpenAIRE

    Prof. Pinhas Shifman

    2014-01-01

    We observe a modern approach that allows for the possibility of a planned separation between sexual relations and procreation. The widespread use of contraceptives created the possibility of sex without reproduction, just as reproductive technologies created the possibility of reproduction without sex. Consequentially, the individual`s ability to control and plan childbirth has expanded, but parallel possibilities have been created for societal intervention in that process. The question wheth...

  8. Interactive Mouse-Driven Animation of Mathematical Processes.

    Science.gov (United States)

    Greenleaf, Newcomb

    1986-01-01

    Provides examples from elementary mathematics principles which illustrate some of the advantages of an interactive mouse-driven animation. Explains the effectiveness of this approach with exercises dealing with a plane of waves and quadratic formulas. (ML)

  9. 'Biogeneric' developmental processes: drivers of major transitions in animal evolution.

    Science.gov (United States)

    Newman, Stuart A

    2016-08-19

    Using three examples drawn from animal systems, I advance the hypothesis that major transitions in multicellular evolution often involved the constitution of new cell-based materials with unprecedented morphogenetic capabilities. I term the materials and formative processes that arise when highly evolved cells are incorporated into mesoscale matter 'biogeneric', to reflect their commonality with, and distinctiveness from, the organizational properties of non-living materials. The first transition arose by the innovation of classical cell-adhesive cadherins with transmembrane linkage to the cytoskeleton and the appearance of the morphogen Wnt, transforming some ancestral unicellular holozoans into 'liquid tissues', and thereby originating the metazoans. The second transition involved the new capabilities, within a basal metazoan population, of producing a mechanically stable basal lamina, and of planar cell polarization. This gave rise to the eumetazoans, initially diploblastic (two-layered) forms, and then with the addition of extracellular matrices promoting epithelial-mesenchymal transformation, three-layered triploblasts. The last example is the fin-to-limb transition. Here, the components of a molecular network that promoted the development of species-idiosyncratic endoskeletal elements in gnathostome ancestors are proposed to have evolved to a dynamical regime in which they constituted a Turing-type reaction-diffusion system capable of organizing the stereotypical arrays of elements of lobe-finned fish and tetrapods. The contrasting implications of the biogeneric materials-based and neo-Darwinian perspectives for understanding major evolutionary transitions are discussed.This article is part of the themed issue 'The major synthetic evolutionary transitions'. PMID:27431521

  10. Innovative non-animal testing strategies for reproductive toxicology: the contribution of Italian partners within the EU project ReProTect

    Directory of Open Access Journals (Sweden)

    Stefano Lorenzetti

    2011-12-01

    Full Text Available Reproductive toxicity, with its many targets and mechanisms, is a complex area of toxicology; thus, the screening and identification of reproductive toxicants is a main scientific challenge for the safety assessment of chemicals, including the European Regulation on Chemicals (REACH. Regulatory agencies recommend the implementation of the 3Rs principle (refinement, reduction, replacement as well as of intelligent testing strategies, through the development of in vitro methods and the use of mechanistic information in the hazard identification and characterization steps of the risk assessment process. The EU Integrated Project ReProTect (6th Framework Programme implemented an array of in vitro tests to study different building blocks of the mammalian reproductive cycle: methodological developments and results on male and female germ cells, prostate and placenta are presented.

  11. Innovative non-animal testing strategies for reproductive toxicology: the contribution of Italian partners within the EU project ReProTect.

    Science.gov (United States)

    Lorenzetti, Stefano; Altieri, Ilaria; Arabi, Sabina; Balduzzi, Donatella; Bechi, Nicoletta; Cordelli, Eugenia; Galli, Cesare; Ietta, Francesca; Modina, Silvia C; Narciso, Laura; Pacchierotti, Francesca; Villani, Paola; Galli, Andrea; Lazzari, Giovanna; Luciano, Alberto Maria; Paulesu, Luana; Spanò, Marcello; Mantovani, Alberto

    2011-01-01

    Reproductive toxicity, with its many targets and mechanisms, is a complex area of toxicology; thus, the screening and identification of reproductive toxicants is a main scientific challenge for the safety assessment of chemicals, including the European Regulation on Chemicals (REACH). Regulatory agencies recommend the implementation of the 3Rs principle (refinement, reduction, replacement) as well as of intelligent testing strategies, through the development of in vitro methods and the use of mechanistic information in the hazard identification and characterization steps of the risk assessment process. The EU Integrated Project ReProTect (6th Framework Programme) implemented an array of in vitro tests to study different building blocks of the mammalian reproductive cycle: methodological developments and results on male and female germ cells, prostate and placenta are presented. PMID:22194079

  12. Animal models and measures of perceptual processing in Schizophrenia

    OpenAIRE

    Siegel, Steven J.; Talpos, John C; GEYER, Mark A

    2013-01-01

    This paper summarizes the discussions regarding animal paradigms for assessing perception at the seventh meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS). A breakout group at the meeting addressed candidate tests in animals that might best parallel the human paradigms selected previously in the CNTRICS program to assess two constructs in the domain of perception: gain control and visual integration. The perception breakout group evaluate...

  13. Use of Assisted Reproductive Technologies for Livestock Development

    Directory of Open Access Journals (Sweden)

    Vikrama Chakravarthi. P and N. Sri Balaji

    2010-10-01

    Full Text Available Genetic improvement of farm animals is a prime concern over the years for researchers. Several reproductive technologies have been employed to achieve this. Assisted reproductive technologies like Artificial insemination, Superovulation, In vitro Fertilization, Embryo Transfer have been introduced to overcome reproductive problems, to increase the offspring from selected female’s and to reduce the generation intervals in farm animals. The progress achieved during the last few years in the assisted reproductive technologies field has been phenomenal. Artificial Insemination (AI is the most effective method being used for the genetic improvement of animals. Reproductive capacity and efficiency has been improved tremendously since the introduction of artificial insemination. The development of cloning using various cells from the animal body has created opening of a fascinating scientific arena. These technologies have been propounded as saviors of indigenous livestock breeds. These alternative reproductive techniques are available not only for manipulation of reproductive processes but also proven to be powerful tools in curbing the spread of vertically transmitted diseases. The successful reproductive technologies such as AI and Embryo transfer need be applied on a large scale, emerging biotechnogies such as MOET, IVF and Cloning provides powerful tool for rapidly changing the animal populations, genetically. This advanced reproduction technologies will definitely play an important role in the future perspective and visions for efficient reproductive performance in livestock. [Vet. World 2010; 3(5.000: 238-240

  14. Radioisotopes In Animal Production Research

    International Nuclear Information System (INIS)

    Animal productivity may be measured among others, in terms of two important physiological processes of reproduction and growth each of which involves a number of integrated disciplines. Both physiological processes are controlled by interactions of genotype and environment. Reproduction essentially involves complex physiological processes controlled by secretions of endocrine glands known as hormones. On the other hand growth is determined largely by availabilty of essential nutrients. In order to achieve good reproductive and growth rates adequate and constant nutrition for livestock include pasture, cereals, tubers and their by-products as well as industrial by-products. While reproduction is essential to provide the required number and replacement of livestock, growth guarantees availability of meat. Another aspect of livestock production is disease control. An animal needs a good health to adequately express its genetic make up and utilize available nutrition. Research in animal production is aimed at improving all aspects of productivity of livestock which include reproduction, growth, milk production, egg production, good semen etc. of livestock. In order to achieve this an understanding of the biochemical and physiological processes occurring in the animal itself, and in the feedstuff fed to the animal as well as the aetiology and control of diseases affecting the animal among other factors, is desirable. A number of methods of investigation have evolved with time. These include colorimetry, spectrophotometry, chromatography, microscopy and raidoisotopic tracer methods. While most of these methods are cumbersome and use equipment with low precision, radioisotopic tracer methods utilize equipment with relatively high precision

  15. Reproductive physiology in eastern snapping turtles (Chelydra serpentina) exposed to runoff from a concentrated animal feeding operation

    Science.gov (United States)

    The eastern snapping turtle (Chelydra serpentina) is widely distributed throughout the eastern and central U.S. and may be a useful model organism to study land use impacts on water quality. We compared the reproductive condition of C. serpentina from a pond impacted by runoff fr...

  16. The reproductive processes of a wild population of the European flat oyster Ostrea edulis in the Solent, UK

    OpenAIRE

    Kamphausen, Lisa Maria

    2012-01-01

    This thesis presents an investigation into the reproductive processes of a collapsing population of the European flat oyster Ostrea edulis in the Solent, UK. Oyster populations are in decline worldwide. Their ecological and economic importance requires research to address the many uncertainties still existing regarding their reproduction and recruitment, in order to manage or restore populations successfully. The Solent oyster population supported a productive local fishery from 1972 to about...

  17. International Society for Wildlife Endocrinology: the future of endocrine measures for reproductive science, animal welfare and conservation biology

    OpenAIRE

    Ganswindt, André; Brown, Janine L.; Elizabeth W. Freeman; Kouba, Andrew J.; Penfold, Linda M.; Santymire, Rachel M.; Vick, Mandi M; Wielebnowski, Nadja; Willis, Erin L.; Milnes, Matthew R.

    2012-01-01

    Hormone analysis is a precise and widely accepted tool for monitoring reproductive function and responses to stressors. Although hormones are present and can be measured in various biological matrices, non-invasive methods have gained popularity over the past 30 years as a more practical approach for assessing ovarian, testicular and, more recently, adrenocortical activity in intractable wildlife species. Non-invasive hormone monitoring also has been key to understanding biological mechanisms...

  18. Processing by the main olfactory system of chemosignals that facilitate mammalian reproduction.

    Science.gov (United States)

    Baum, Michael J; Cherry, James A

    2015-02-01

    This article is part of a Special Issue "Chemosignals and Reproduction". Most mammalian species possess two parallel circuits that process olfactory information. One of these circuits, the accessory system, originates with sensory neurons in the vomeronasal organ (VNO). This system has long been known to detect non-volatile pheromonal odorants from conspecifics that influence numerous aspects of social communication, including sexual attraction and mating as well as the release of luteinizing hormone from the pituitary gland. A second circuit, the main olfactory system, originates with sensory neurons in the main olfactory epithelium (MOE). This system detects a wide range of non-pheromonal odors relevant to survival (e.g., food and predator odors). Over the past decade evidence has accrued showing that the main olfactory system also detects a range of volatile odorants that function as pheromones to facilitate mate recognition and activate the hypothalamic-pituitary-gonadal neuroendocrine axis. We review early studies as well as the new literature supporting the view that the main olfactory system processes a variety of different pheromonal cues that facilitate mammalian reproduction. PMID:24929017

  19. Reproduction of a new inferior vena cava thrombosis model and study of the evolutionary process of thrombolysis in rats

    Directory of Open Access Journals (Sweden)

    Jian FU

    2015-10-01

    Full Text Available Objective To investigate the reproduction of a new model of thrombosis of inferior vena cava (IVC, and explore the natural process of thrombolysis and its mechanism in rats. Methods Forty-eight SD rats were randomly classified into experimental group and control group. In the experimental group, the lumen of the vena cava was blocked by about 80%-90% with a ligature of IVC below the left renal vein, and then the animals were redivided into three subgroups (n=12, each. In group A, the IVC endothelium was damaged and its tributaries were ligated. In group B, the IVC endothelium was damaged and its tributaries were not ligated. In group C, no damage was done to the endothelium of the IVC but all its tributaries were ligated. A sham-operated group served as control. The length and weight of the vinous thrombus and the percentage of the IVC luminal area were compared after operation to determine the optimum animal model of venous thrombosis. According to the best mode to establish the model, the thrombus specimens were collected and detected by HE and Masson staining, and the ED-1 expressions were examined by immunohistochemical staining after thrombus formation in 30 rats. The natural evolution of intravenous thrombolysis was analyzed dynamically and the cell types involved in this process were observed. Results Gross observation showed that the experimental group was successfully induced thrombus formation. The thrombus length and weight in group A was significantly higher than that in group B and group C, and no difference between group B and C. The thrombus area in group A was significantly higher than that in groups B and group C, which identified the group A was the optimal model group of venous thrombosis. In the group reproduced by the best mode of the model, HE and Masson staining results showed that new capillaries and the components of collagen and extracellular matrix increased gradually with the passage of time in the process of

  20. Glycobiology of Reproductive Processes in Marine Animals: The State of the Art

    OpenAIRE

    Maria Costantini; Alessandra Gallo

    2012-01-01

    Glycobiology is the study of complex carbohydrates in biological systems and represents a developing field of science that has made huge advances in the last half century. In fact, it combines all branches of biomedical research, revealing the vast and diverse forms of carbohydrate structures that exist in nature. Advances in structure determination have enabled scientists to study the function of complex carbohydrates in more depth and to determine the role that they play in a wide range of ...

  1. 9 CFR 95.4 - Restrictions on the importation of processed animal protein, offal, tankage, fat, glands, certain...

    Science.gov (United States)

    2010-01-01

    ... Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EXPORTATION AND IMPORTATION... processed animal protein, offal, tankage, fat, glands, certain tallow other than tallow derivatives, and... importation of processed animal protein, offal, tankage, fat, glands, certain tallow other than...

  2. Improved Process Quality through Certification Systems: An Assessment of Selected Animal Welfare Labels

    Directory of Open Access Journals (Sweden)

    Heinke Heise

    2014-07-01

    Full Text Available The process quality of food products is currently the subject of increased attention. In the area of meat production, public discussion has centered on perceived low standards of animal welfare. Besides an increase in legislative regulations, improved animal welfare standards are most frequently achieved through the establishment of socalled animal welfare labels. So far these labeling concepts have not been substantially evaluated in terms of how well they carry out their goal of improving process quality in agricultural animal husbandry. This paper will use a recognized list of criteria to evaluate selected animal welfare labels. Results show that competing labels vary strongly regarding the improvement of process quality. This has far‐reaching effects not only for consumers andother label users, but also for companies that want to enter the animal welfare segment of the meat market.

  3. The Narrative Reproduction of Contemporary Montenegrin Identity in The Process of Euroatlantic Intergrations (Part I

    Directory of Open Access Journals (Sweden)

    Branko Banović

    2016-03-01

    Full Text Available If we conceptualize reality as a large narrative we “build ourselves into” as social beings, and consider social activities and identities as narratively mediated, the full extent of the capacity of narratives in the creation, shaping, transmission and reconstruction of contemporary social identities, as well as the reproduction of the concept of nation in everyday life becomes apparent. The imagined Euro- Atlantic future of Montenegro demands certain narrative interpretations of the past, which, in latter stages tend to become meta-narratives susceptible to consensus. The linkage of significant historical events to the process of Euro-Atlantic integrations of Montenegro is preformed through different meta-discursive practices, most often through ceremonial evocations of memories of significant events from the recent as well as further history of Montenegro. In this context, celebrations of Statehood Day and Independence Day are especially important, as they serve as reminders of the decisions of the Congress of Berlin, the Podgorica Assembly, the antifascist struggle of World War II and the independence of Montenegro attained through the referendum held in 2006. The clearly defined key points, along with the logical coherence the narrative is based on, provide the narrative with a certain “flexibility” which enables it to take in new elements. Narrative interpretations of the past have a significant role in the reproduction of the nation, as well as the shaping and consolidation of a desirable national identity, while the established narrative continuity between the past, present and imagined Euro-Atlantic future of Montenegro emerges as the “official” mediator in the reproduction of contemporary Montenegrin identity in the process of Euro-Atlantic integration. In order to fully comprehend this narrative, it is advisable to conceptualize it both in a synchronic as well as a diachronic perspective, as can be shown in two charts which

  4. Associative structures in animal learning: dissociating elemental and configural processes.

    Science.gov (United States)

    Honey, Robert C; Iordanova, Mihaela D; Good, Mark

    2014-02-01

    The central concern of associative learning theory is to provide an account of behavioral adaptation that is parsimonious in addressing three key questions: (1) under what conditions does learning occur, (2) what are the associative structures involved, and (3) how do these affect behavior? The principle focus here is on the second question, concerning associative structures, but we will have cause to touch on the others in passing. This question is one that has exercised theorists since Pavlov's descriptions of the conditioning process, where he identifies the shared significance of the study of conditioned reflexes for psychologists and neuroscientists alike. PMID:23769767

  5. Analysis of effect of harvest corn plant in different stages of reproductive and processing of grain on the quality of silage

    Directory of Open Access Journals (Sweden)

    Fabiano Marafon

    2015-10-01

    Full Text Available The experiment was conducted at the Department of Animal Production (NUPRAN State University Midwest (UNICENTRO, with the objective of evaluate the effect of harvesting the maize plant at different reproductive stages and with different grains process on dry matter digestibility, neutral detergent fiber digestibility and animal performance. The experimental design was completely randomized, with four treatments and four replications, where each replication consisted of a pen with two steers, totaling sixteen experimental units. During the silage confection, homogeneous and representative samples from processed plants were collected, part intended for chemical analyses and inserted part in “bags” silo, putting these in the profile of each bunker silo, being considered as experimental units. The experiment lasted 84 days after opining de bunker silos, being 14 days for adaption, followed by 4 periods of 21 days. Thus, silage harvested at dough stage showed higher values of in vitro digestibility of dry matter and neutral detergent fiber. The use of corn silage harvested at R5 stage facilitated better animal performance with consequent transformation of dry matter consumed in daily weight gain.

  6. Bovine reproduction in tropical environment

    International Nuclear Information System (INIS)

    In this document it has met relating data to the reproduction of bovine and their handling for the man that it can serve as norms to judge reproductive efficiency but always view in the aspect of the nutritious, climatic circumstances and of handling under which met. Under the previous description one can say that the fertility is the resultant of the interaction among the inheritance, the means and the handling, they vary in particular for each region and property. The fertility can be good, regulate or bad in the measure in that the factors that intervene. The environmental effect on the reproductive processes of the cow represents 80 percent of the variation factors and they include climate, effect of the light, effect of the temperature, effect of the nutritious contribution, effect of psychological factors: the loss of the tendency to the seasonal reproduction is in fact an answer from the animals to its association with the man. The influence of the environment and the feeding of the animals are more intense in the females than in the males, being evidenced that the reproduction control is under the influence hormonal joint with the nutrition. An appropriate nutrition is prerequisite for the beginning of the sexual maturation with an appropriate weight and corporal condition. It is also described the effect and the relationship of the energy contribution about the fertility, the restart of the ovarian activity, its cause of the continuation of the interval childbirth-conception, silent ovulation, organic ancestry and interval among childbirths

  7. Reproduction and appraisal of an animal model of acute myelomonocytic leukemia in the CB6F1generation mice

    Directory of Open Access Journals (Sweden)

    Hong-li ZUO

    2011-01-01

    Full Text Available Objective To reproduce an acute myelomonocytic leukemia M4(AML-M4animal model with the CB6F1generation mice.Methods The CB6F1(BALB/c C57BL/6mice were inoculated intravenously with different amounts(1×106,2×106,5×106,1 ×107of WEHI-3cells,a cell line of myelomonocytic leukemia.The correlation between the animal survival and the inoculated amount was analyzed.The mice,inoculated with 1×106 cells,were selected for observation of leukemia onset,and sampled for routine blood test.Four weeks after inoculation,the peripheral blood was collected from moribund mice,morphological observation was made in blood smears,and immunophenotype and major histocompatibility complex(MHCwas determined;the marrow cells were collected for morphological observation,and immunochemical and karyotype analysas were made.The liver,spleen,kidney,lung,heart and brain were obtained for pathological observation.The results of all the observations and determinations were then comprehensively analyzed to evaluate the authenticity of the established AML-M4mice model.Ara-C,in a dosage of 50mg/kg or 100mg/kg,was intraperitoneally injected to the model mice for observation of the disease course and survival of the animals,and to evaluate the sensitivity of model mice to the chemotherapeutics.Normal mice were selected to serve as control in all the experiments.Results Mice inoculated with different amount of WEHI-3cells died of leukemia 17to 33days after inoculation,and a negative correlation between the inoculated amount and the survival time of animals was observed(r=-0.936,P < 0.01.Those inoculated with 1×106 cells survived for 25~33(28.50±1.87days.Four weeks after inoculation,the WBC counts of peripheral blood increased obviously with a peak value of 81×109/L,in the moribund leukemic mice,which was significantly different from that of normal control(P < 0.05.Leukemia cells with larger size and irregular shape were observed in the blood smear.A large number of primary and

  8. A Tissue Retrieval and Postharvest Processing Regimen for Rodent Reproductive Tissues Compatible with Long-Term Storage on the International Space Station and Postflight Biospecimen Sharing Program

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    Vijayalaxmi Gupta

    2015-01-01

    Full Text Available Collection and processing of tissues to preserve space flight effects from animals after return to Earth is challenging. Specimens must be harvested with minimal time after landing to minimize postflight readaptation alterations in protein expression/translation, posttranslational modifications, and expression, as well as changes in gene expression and tissue histological degradation after euthanasia. We report the development of a widely applicable strategy for determining the window of optimal species-specific and tissue-specific posteuthanasia harvest that can be utilized to integrate into multi-investigator Biospecimen Sharing Programs. We also determined methods for ISS-compatible long-term tissue storage (10 months at −80°C that yield recovery of high quality mRNA and protein for western analysis after sample return. Our focus was reproductive tissues. The time following euthanasia where tissues could be collected and histological integrity was maintained varied with tissue and species ranging between 1 and 3 hours. RNA quality was preserved in key reproductive tissues fixed in RNAlater up to 40 min after euthanasia. Postfixation processing was also standardized for safe shipment back to our laboratory. Our strategy can be adapted for other tissues under NASA’s Biospecimen Sharing Program or similar multi-investigator tissue sharing opportunities.

  9. Unconscious Processing of Negative Animals and Objects: Role of the Amygdala Revealed by fMRI

    OpenAIRE

    Fang, Zhiyong; Li, Han; Chen, Gang; Yang, Jiongjiong

    2016-01-01

    Previous studies have shown that emotional stimuli can be processed through the amygdala without conscious awareness. The amygdala is also involved in processing animate and social information. However, it is unclear whether different categories of pictures (e.g., animals, objects) elicit different activity in the amygdale and other regions without conscious awareness. The objective of this study was to explore whether the factors of category, emotion and picture context modulate brain activa...

  10. Animal Sociology and a Natural Economy of the Body Politic, Part II: The Past Is the Contested Zone: Human Nature and Theories of Production and Reproduction in Primate Behavior Studies.

    Science.gov (United States)

    Haraway, Donna

    1978-01-01

    Theories of animal and human society based on sex and reproduction have been powerful in legitimating beliefs in the natural necessity of aggression, competition, and hierarchy. Feminists attempting to answer this bias are caught in a political-scientific struggle to formulate and articulate adequate biosocial theories. (Author/KR)

  11. Quaternary ammonium disinfectants cause subfertility in mice by targeting both male and female reproductive processes.

    Science.gov (United States)

    Melin, Vanessa E; Melin, Travis E; Dessify, Brian J; Nguyen, Christina T; Shea, Caroline S; Hrubec, Terry C

    2016-01-01

    Alkyl dimethyl benzyl ammonium chloride (ADBAC) and didecyl dimethyl ammonium chloride (DDAC) are common ingredients in household bathroom and kitchen cleaning sprays. ADBAC+DDAC cause reproductive toxicity in mice. The aim of the present study was to investigate gender-specific reproductive effects from ADBAC+DDAC. Female reproduction was assessed through ovulation, oocyte implantation, and estrus cycling. Male reproductive function was assessed by sperm concentration, motility, and viability. Numbers of corpora lutea were not different after 2 weeks, but decreased after 8 weeks of ADBAC+DDAC exposure. Dams exposed for 5 weeks to ADBAC+DDAC spent significantly less time in estrus. ADBAC+DDAC exposed males exhibited declines in both sperm concentration and motility, but not sperm viability. Subfertility in mice from ADBAC+DDAC exposure is, therefore, mediated through reproductive disturbances in both females and males. While the effect of ADBAC+DDAC exposure on human health is unclear, widespread exposure necessitates further consideration of their potential reproductive toxicity. PMID:26582257

  12. Cross-Cultural Influences on Rhythm Processing: Reproduction, Discrimination, and Beat Tapping

    Directory of Open Access Journals (Sweden)

    Daniel J Cameron

    2015-04-01

    Full Text Available The structures of musical rhythm differ between cultures, despite the fact that the ability to synchronize one’s movements to musical rhythms appears to be universal. To measure the influence of culture on rhythm processing, we tested East African and North American adults on the perception, production, and beat tapping of rhythms derived from East African and Western music. To assess rhythm perception, participants identified whether pairs of rhythms were same or different. To assess rhythm production, participants reproduced rhythms after hearing them. To assess beat tapping, participants tapped the beat along with repeated rhythms. We expected that performance in all three tasks would be influenced both by the culture of the participant and by the culture of the rhythm. Specifically, we predicted that a participant’s ability to discriminate, reproduce, and accurately tap the beat would be better for rhythms from their own culture than for rhythms from another culture. In the rhythm discrimination task, there were no differences in discriminating culturally familiar and unfamiliar rhythms. In the rhythm reproduction task, both groups reproduced East African rhythms more accurately than Western rhythms, but East African participants also showed an effect of cultural familiarity, leading to a significant interaction. In the beat tapping task, participants in both groups tapped the beat more accurately for culturally familiar than unfamiliar rhythms. The results demonstrate that culture does influence the processing of musical rhythm. In terms of the function of musical rhythm, our results are consistent with theories that musical rhythm enables synchronization. Musical rhythm may foster musical cultural identity by enabling within-group synchronization to music, perhaps supporting social cohesion.

  13. The emergence of semantic categorization in early visual processing: ERP indices of animal vs. artifact recognition

    Directory of Open Access Journals (Sweden)

    Del Zotto Marzia

    2007-04-01

    Full Text Available Abstract Background Neuroimaging and neuropsychological literature show functional dissociations in brain activity during processing of stimuli belonging to different semantic categories (e.g., animals, tools, faces, places, but little information is available about the time course of object perceptual categorization. The aim of the study was to provide information about the timing of processing stimuli from different semantic domains, without using verbal or naming paradigms, in order to observe the emergence of non-linguistic conceptual knowledge in the ventral stream visual pathway. Event related potentials (ERPs were recorded in 18 healthy right-handed individuals as they performed a perceptual categorization task on 672 pairs of images of animals and man-made objects (i.e., artifacts. Results Behavioral responses to animal stimuli were ~50 ms faster and more accurate than those to artifacts. At early processing stages (120–180 ms the right occipital-temporal cortex was more activated in response to animals than to artifacts as indexed by posterior N1 response, while frontal/central N1 (130–160 showed the opposite pattern. In the next processing stage (200–260 the response was stronger to artifacts and usable items at anterior temporal sites. The P300 component was smaller, and the central/parietal N400 component was larger to artifacts than to animals. Conclusion The effect of animal and artifact categorization emerged at ~150 ms over the right occipital-temporal area as a stronger response of the ventral stream to animate, homomorphic, entities with faces and legs. The larger frontal/central N1 and the subsequent temporal activation for inanimate objects might reflect the prevalence of a functional rather than perceptual representation of manipulable tools compared to animals. Late ERP effects might reflect semantic integration and cognitive updating processes. Overall, the data are compatible with a modality-specific semantic memory

  14. Simulation of between-farm transmission of porcine reproductive and respiratory syndrome virus in Ontario, Canada using the North American Animal Disease Spread Model.

    Science.gov (United States)

    Thakur, Krishna K; Revie, Crawford W; Hurnik, Daniel; Poljak, Zvonimir; Sanchez, Javier

    2015-03-01

    Porcine reproductive and respiratory syndrome (PRRS), a viral disease of swine, has major economic impacts on the swine industry. The North American Animal Disease Spread Model (NAADSM) is a spatial, stochastic, farm level state-transition modeling framework originally developed to simulate highly contagious and foreign livestock diseases. The objectives of this study were to develop a model to simulate between-farm spread of a homologous strain of PRRS virus in Ontario swine farms via direct (animal movement) and indirect (sharing of trucks between farms) contacts using the NAADSM and to compare the patterns and extent of outbreak under different simulated conditions. A total of 2552 swine farms in Ontario province were allocated to each census division of Ontario and geo-locations of the farms were randomly generated within the agriculture land of each Census Division. Contact rates among different production types were obtained using pig movement information from four regions in Canada. A total of 24 scenarios were developed involving various direct (movement of infected animals) and indirect (pig transportation trucks) contact parameters in combination with alternating the production type of the farm in which the infection was seeded. Outbreaks were simulated for one year with 1000 replications. The median number of farms infected, proportion of farms with multiple outbreaks and time to reach the peak epidemic were used to compare the size, progression and extent of outbreaks. Scenarios involving spread only by direct contact between farms resulted in outbreaks where the median percentage of infected farms ranged from 31.5 to 37% of all farms. In scenarios with both direct and indirect contact, the median percentage of infected farms increased to a range from 41.6 to 48.6%. Furthermore, scenarios with both direct and indirect contact resulted in a 44% increase in median epidemic size when compared to the direct contact scenarios. Incorporation of both animal

  15. Variability driven animacy effects: Evidence of structural, not conceptual differences in processing animates and inanimates

    Directory of Open Access Journals (Sweden)

    Vanja Ković

    2010-03-01

    Full Text Available The present eye-tracking study demonstrates that when animate and inanimate object pictures are presented within a single-study, there are no systematic differences between processing these two categories objects. Although participants were taking less time to initiate their first gaze towards animate than to inanimate objects, a result compatible with findings of Proverbio et al. (2007, it turned out that this quicker initiation of the first look in animates was driven by mammals and reptiles only and did not apply to insects or aquatic animals, most probably due to the structural differences within these subcategories. Fixations in this study do not cluster around certain features or areas of the objects for either animate or inanimate categories. Moreover, detailed analysis of looking behaviour does not reveal a clear animateinanimate distinction. Thus, given the failure of finding systematic differences between animates and inanimates when assessed using various looking behaviour measurements, the results do not support the prediction from modality specific conceptual account. In fact, these results are more in agreement with an alternative, distributed account of semantic representation that explains processing differences by structural differences between animate and inanimate objects.

  16. Measuring reproductive performance in dairy cattle

    International Nuclear Information System (INIS)

    Dairy herd profitability is closely related to reproductive performance, which is, in turn, strongly influenced by management. A regular monitoring of reproductive efficiency is essential to assess management and to avoid financial losses due poor performance. The measures for this efficiency commonly used are either not based on all animals in the herd, only reflect part of the reproductive process or influence each other. Thus, obtaining an overall picture of the herd's reproductive performance requires combination of various individual components into an integrated index. The minimum measures that should be included in an integrated index for herd fertility are: average calving to pregnancy interval, culling rate, services per conception, age at first calving and percentage of stillborn calves. Ideally, the resulting calculation should emphasize the estimated financial losses or gains due to deviations from the targets set for these measures. Any herd fertility summary of projection might indicated reproductive performance but not their causes. For the identification of these causes, the length of the voluntary waiting period, the efficiency of heat detection, the services per conception, the culling rate, the age at first calving and the percentage abortions and stillbirths need to be evaluated. An additional problem with the measures of herd reproductive performance is that they indicate past reproductive performance, rather than reflect current changes of future expectations. The ''Projected Minimum Average Calving-to-Pregnancy Interval'' is the best prediction for future reproductive performance of a herd, but must be combined with the ''Integrated Fertility Index'' to provide a complete picture. (author). 17 refs

  17. Duplicating the fine art reproduction process: the technology used for guerilla ink-jet printing

    Science.gov (United States)

    Herron, Stephen

    1998-12-01

    Accurate, automatic color reproduction is the goal of much of color technology. However, there is a need to improve reproduction in only the luminous or gray axis. Quadtone reproduction takes advantage of the four device CMYK color planes to provide greater gray-scale depth within the limitations of 8-bit per channel band-width. 'Quadtone' refers to photos reproduced using four tones of the same colorant. It is the printed imposition of four carefully selected shades of ink that result in a greater number of densities. Guerilla printing is a collection of algorithms using the CMYK channels to simulate traditional photography on an inkjet printer. Guerilla printing increases density values, defines detail and produces near continuous-tone screens.

  18. Lysophosphatidic Acid (LPA Signaling in Human and Ruminant Reproductive Tract

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    Izabela Wocławek-Potocka

    2014-01-01

    Full Text Available Lysophosphatidic acid (LPA through activating its G protein-coupled receptors (LPAR 1–6 exerts diverse cellular effects that in turn influence several physiological processes including reproductive function of the female. Studies in various species of animals and also in humans have identified important roles for the receptor-mediated LPA signaling in multiple aspects of human and animal reproductive tract function. These aspects range from ovarian and uterine function, estrous cycle regulation, early embryo development, embryo implantation, decidualization to pregnancy maintenance and parturition. LPA signaling can also have pathological consequences, influencing aspects of endometriosis and reproductive tissue associated tumors. The review describes recent progress in LPA signaling research relevant to human and ruminant reproduction, pointing at the cow as a relevant model to study LPA influence on the human reproductive performance.

  19. Critical Analysis of Assessment Studies of the Animal Ethics Review Process

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    Orsolya Varga

    2013-09-01

    Full Text Available In many countries the approval of animal research projects depends on the decisions of Animal Ethics Committees (AEC’s, which review the projects. An animal ethics review is performed as part of the authorization process and therefore performed routinely, but comprehensive information about how well the review system works is not available. This paper reviews studies that assess the performance of animal ethics committees by using Donabedian’s structure-process-outcome model. The paper points out that it is well recognised that AECs differ in structure, in their decision-making methods, in the time they take to review proposals and that they also make inconsistent decisions. On the other hand, we know little about the quality of outcomes, and to what extent decisions have been incorporated into daily scientific activity, and we know almost nothing about how well AECs work from the animal protection point of view. In order to emphasise this viewpoint in the assessment of AECs, the paper provides an example of measures for outcome assessment. The animal suffering is considered as a potential measure for outcome assessment of the ethics review. Although this approach has limitations, outcome assessment would significantly increase our understanding of the performance of AECs.

  20. Critical Analysis of Assessment Studies of the Animal Ethics Review Process.

    Science.gov (United States)

    Varga, Orsolya

    2013-01-01

    In many countries the approval of animal research projects depends on the decisions of Animal Ethics Committees (AEC's), which review the projects. An animal ethics review is performed as part of the authorization process and therefore performed routinely, but comprehensive information about how well the review system works is not available. This paper reviews studies that assess the performance of animal ethics committees by using Donabedian's structure-process-outcome model. The paper points out that it is well recognised that AECs differ in structure, in their decision-making methods, in the time they take to review proposals and that they also make inconsistent decisions. On the other hand, we know little about the quality of outcomes, and to what extent decisions have been incorporated into daily scientific activity, and we know almost nothing about how well AECs work from the animal protection point of view. In order to emphasise this viewpoint in the assessment of AECs, the paper provides an example of measures for outcome assessment. The animal suffering is considered as a potential measure for outcome assessment of the ethics review. Although this approach has limitations, outcome assessment would significantly increase our understanding of the performance of AECs. PMID:26479540

  1. Environmental processes leading to the presence of organically bound plutonium in plant tissues consumed by animals

    International Nuclear Information System (INIS)

    The long half-life of plutonium (Pu) and its possible entry into the environment as a result of the nuclear fuel cycle necessitate estimation of its availability to animals over thousands of years. A major uncertainty in this evaluation arises from the effects of physical and biogeochemical processes on Pu form and biological availability. However, a general understanding of the principal mechanisms governing Pu behavior in the terrestrial ingestion pathway is developing which ultimately should serve as a framework for estimation of long-term availability to animals. This review briefly integrates and synthesizes present information on the chemical/biochemical processes governing the form of Pu in soils and plants and the relationships of these phenomena to gut absorption in animals. A proposed model for Pu behavior will be used as a framework for integration of current knowledge

  2. New developments in the detection and identification of processed animal proteins in feeds

    NARCIS (Netherlands)

    Raamsdonk, van L.W.D.; Holst, von C.; Baeten, V.; Berben, G.; Boix, A.; Jong, de J.

    2007-01-01

    It is generally accepted that the most likely route of infection of cattle with bovine spongiform encephalopathy (BSE) is by consumption of feeds containing low levels of processed animal proteins (PAPs). This likely route of infection resulted in feed bans, which were primarily aimed at ruminant fe

  3. The effects of tualang honey on female reproductive organs, tibia bone and hormonal profile in ovariectomised rats - animal model for menopause

    Directory of Open Access Journals (Sweden)

    Sirajudeen Kuttulebbai NM

    2010-12-01

    Full Text Available Abstract Background Honey is a highly nutritional natural product that has been widely used in folk medicine for a number of therapeutic purposes. We evaluated whether Malaysian Tualang honey (AgroMas, Malaysia was effective in reducing menopausal syndrome in ovariectomised female rats; an animal model for menopause. Methods The rats were divided into two control groups and three test groups. The control groups were sham-operated (SH and ovariectomised (OVX rats. The SH and OVX control rats were fed on 0.5 ml of distill water. The rats in the test groups were fed with low dose 0.2 g/kg (THL, medium dose, 1.0 g/kg (THM and high dose 2.0 g/kg (THH of Tualang honey in 0.5 ml of distill water. The administration was given by oral gavage once daily for 2 weeks. The reproductive organs (uterus and vagina, tibia bone and aorta were taken for histopathological examination while serum for hormonal assays. Results Administration of Tualang honey for 2 weeks to ovariectomised rats significantly increased the weight of the uterus and the thickness of vaginal epithelium, restored the morphology of the tibia bones and reduced the body weight compared to rats in the ovariectomised group. The levels of estradiol and progesterone, in honey treated groups were markedly lower than that in the OVX group. At low doses (0.2 g/kg; THL group of Tualang honey there was an increased in serum free testosterone levels compared to OVX group (P Conclusions Tualang honey was shown to have beneficial effects on menopausal (ovariectomised rats by preventing uterine atrophy, increased bone density and suppression of increased body weight. Honey could be an alternative to HRT.

  4. The emergence of semantic categorization in early visual processing: ERP indices of animal vs. artifact recognition

    OpenAIRE

    Del Zotto Marzia; Proverbio Alice M; Zani Alberto

    2007-01-01

    Abstract Background Neuroimaging and neuropsychological literature show functional dissociations in brain activity during processing of stimuli belonging to different semantic categories (e.g., animals, tools, faces, places), but little information is available about the time course of object perceptual categorization. The aim of the study was to provide information about the timing of processing stimuli from different semantic domains, without using verbal or naming paradigms, in order to ob...

  5. Approaches to Optimizing Animal Cell Culture Process: Substrate Metabolism Regulation and Protein Expression Improvement

    Science.gov (United States)

    Zhang, Yuanxing

    Some high value proteins and vaccines for medical and veterinary applications by animal cell culture have an increasing market in China. In order to meet the demands of large-scale productions of proteins and vaccines, animal cell culture technology has been widely developed. In general, an animal cell culture process can be divided into two stages in a batch culture. In cell growth stage a high specific growth rate is expected to achieve a high cell density. In production stage a high specific production rate is stressed for the expression and secretion of qualified protein or replication of virus. It is always critical to maintain high cell viability in fed-batch and perfusion cultures. More concern has been focused on two points by the researchers in China. First, the cell metabolism of substrates is analyzed and the accumulation of toxic by-products is decreased through regulating cell metabolism in the culture process. Second, some important factors effecting protein expression are understood at the molecular level and the production ability of protein is improved. In pace with the rapid development of large-scale cell culture for the production of vaccines, antibodies and other recombinant proteins in China, the medium design and process optimization based on cell metabolism regulation and protein expression improvement will play an important role. The chapter outlines the main advances in metabolic regulation of cell and expression improvement of protein in animal cell culture in recent years.

  6. The Natural Reproduction and Economic Reproduction of Agriculture

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    In the perspective of Marx’s materialism,the thesis expounds the natural reproduction and economic reproduction of agriculture,and analyzes the relationship between the two production processes.The natural reproduction of agriculture,the contradicted unification of agricultural organism and natural environment,conforms to natural law and has the specific objective environmental requirements.The economic reproduction of agriculture is the process of people’s production and labor which takes keeping the life vitality of agricultural organism as objective,including the reproduction of agricultural productivity and the reproduction of agricultural production relations.The agricultural productivity comprises social productivity and natural productivity.The process of agricultural economic reproduction must conform to the objective natural law and economic law.The relationship of agricultural natural reproduction and economic reproduction is that the agricultural natural reproduction process is intertwined with economic reproduction process;the variation trend of agricultural natural reproduction ability and economic reproduction ability is identical;the agricultural economic reproduction dominates over the natural reproduction.

  7. Torpor during reproduction in mammals and birds: dealing with an energetic conundrum.

    Science.gov (United States)

    McAllan, B M; Geiser, Fritz

    2014-09-01

    Torpor and reproduction in mammals and birds are widely viewed as mutually exclusive processes because of opposing energetic and hormonal demands. However, the reported number of heterothermic species that express torpor during reproduction is ever increasing, to some extent because of recent work on free-ranging animals. We summarize current knowledge about those heterothermic mammals that do not express torpor during reproduction and, in contrast, examine those heterothermic birds and mammals that do use torpor during reproduction. Incompatibility between torpor and reproduction occurs mainly in high-latitude sciurid and cricetid rodents, which live in strongly seasonal, but predictably productive habitats in summer. In contrast, torpor during incubation, brooding, pregnancy, or lactation occurs in nightjars, hummingbirds, echidnas, several marsupials, tenrecs, hedgehogs, bats, carnivores, mouse lemurs, and dormice. Animals that enter torpor during reproduction often are found in unpredictable habitats, in which seasonal availability of food can be cut short by changes in weather, or are species that reproduce fully or partially during winter. Moreover, animals that use torpor during the reproductive period have relatively low reproductive costs, are largely insectivorous, carnivorous, or nectarivorous, and thus rely on food that can be unpredictable or strongly seasonal. These species with relatively unpredictable food supplies must gain an advantage by using torpor during reproduction because the main cost is an extension of the reproductive period; the benefit is increased survival of parent and offspring, and thus fitness. PMID:24973362

  8. Innovative non-animal testing strategies for reproductive toxicology: the contribution of Italian partners within the EU project ReProTect

    OpenAIRE

    Stefano Lorenzetti; Ilaria Altieri; Sabina Arabi; Donatella Balduzzi; Nicoletta Bechi; Eugenia Cordelli; Cesare Galli; Francesca Ietta; Modina, Silvia C.; Laura Narciso; Francesca Pacchierotti; Paola Villani; Andrea Galli; Giovanna Lazzari; Alberto Maria Luciano

    2011-01-01

    Reproductive toxicity, with its many targets and mechanisms, is a complex area of toxicology; thus, the screening and identification of reproductive toxicants is a main scientific challenge for the safety assessment of chemicals, including the European Regulation on Chemicals (REACH). Regulatory agencies recommend the implementation of the 3Rs principle (refinement, reduction, replacement) as well as of intelligent testing strategies, through the development of in vitro methods and the use of...

  9. Reproductive function of monkeys subjected to chronic irradiation

    International Nuclear Information System (INIS)

    Marked functional disorders have been detected in reproductive glands of eight female monkeys (as compared to twelve control animals) subjected to protracted (up to eight years) irradiation (cumulative doses 826-3282 R). Irradiated monkeys exhibited a drastically decreased reproductive capacity, early menopause and sterility. Irradiation of preadolescent animals inhibited, in most cases, the puberty processes and disturbed sex cycles. Structural disorders in sex glands, inhibition of the processes of maturation and ovulation of folloculi, death of the mass of germ cells, atypical vegetations of the integmentary epithelium, sclerosing and cystic degeneration of the glandular tissue have been revealed

  10. Coordination of Group Movements in Wild Red-fronted Lemurs (Eulemur rufifrons): Processes and Influence of Ecological and Reproductive Seasonality.

    Science.gov (United States)

    Pyritz, Lennart W; Kappeler, Peter M; Fichtel, Claudia

    2011-12-01

    Group-living species have to coordinate collective actions to maintain cohesion. In primates, spatial movements represent a meaningful model to study group coordination processes across different socio-ecological contexts. We studied 4 groups of red-fronted lemurs (Eulemur rufifrons) in Kirindy Forest, Madagascar, between 2008 and 2010 across different ecological and reproductive seasons. We collected data on ranging patterns using GPS collars and observational data on different predefined parameters of group movements, including initiation, leadership, followership, overtaking events, termination, and travel distances. Cohesion of these relatively small, egalitarian lemur groups was high year-round, but daily path length and home range size varied considerably between ecological seasons, presumably due to long-distance migrations of some groups at the beginning of the rainy season. Individuals of different age and sex classes successfully initiated group movements. However, stable female leadership prevailed year-round, irrespective of ecological and reproductive season, which might be due to higher or more specific energetic requirements of reproduction. In contrast to lemur species with a more despotic social structure, female red-fronted lemurs did not recruit more followers than males. Adult leaders recruited more followers than subadult ones. Further, recruitment success was higher during the peak of the dry season, when predation risk appeared to be higher. Distances of single group movements did not depend on the initiator's sex and age or on ecological seasons. Our results provide new insights into seasonal variability of coordination processes and the role of social dominance in lemur group movements, thereby contributing to a comparative perspective from a primate radiation that evolved group living independently of anthropoids. PMID:22207771

  11. Study on upgrading of oil palm wastes to animal feeds by radiation and fermentation processing

    International Nuclear Information System (INIS)

    Upgrading of oil palm empty fruit bunch (EFB), which is a main by-product of palm oil industry, to animal feeds by radiation pasteurization and fermentation was investigated for recycling the agro-resources and reducing the environmental pollution. The following results were obtained: 1) The necessary dose for pasteurization of EFB contaminated by various microorganisms including aflatoxin producing fungi was determined as 10 kGy. The chemical and biological properties of EFB were changed little by irradiation up to 50 kGy. 2) In the fermentation process, Pleurotus sajor-caju was selected as the most effective fungi and the optimum condition for fermentation was clarified. The process of fermentation in suspension was also established for the liquid seed preparation. 3) The digestibility and nutritional value of fermented products were evaluated as ruminant animal feeds and the mushroom can be produced as by-product. 4) The pilot plant named Sterifeed was built at MINT and a large volume production has been trying for animal feeding test and economical evaluation. It is expected to develop the process for the commercial use in Malaysia and to expand the technique to Asian region through UNDP/RCA/IAEA project. (author)

  12. Study on upgrading of oil palm wastes to animal feeds by radiation and fermentation processing

    Energy Technology Data Exchange (ETDEWEB)

    Kume, Tamikazu; Matsuhashi, Shinpei; Ito, Hitoshi [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment] [and others

    1998-03-01

    Upgrading of oil palm empty fruit bunch (EFB), which is a main by-product of palm oil industry, to animal feeds by radiation pasteurization and fermentation was investigated for recycling the agro-resources and reducing the environmental pollution. The following results were obtained: (1) The necessary dose for pasteurization of EFB contaminated by various microorganisms including aflatoxin producing fungi was determined as 10 kGy. The chemical and biological properties of EFB were changed little by irradiation up to 50 kGy. (2) In the fermentation process, Pleurotus sajor-caju was selected as the most effective fungi and the optimum condition for fermentation was clarified. The process of fermentation in suspension was also established for the liquid seed preparation. (3) The digestibility and nutritional value of fermented products were evaluated as ruminant animal feeds and the mushroom can be produced as by-product. (4) The pilot plant named Sterifeed was built at MINT and a large volume production has been trying for animal feeding test and economical evaluation. It is expected to develop the process for the commercial use in Malaysia and to expand the technique to Asian region through UNDP/RCA/IAEA project. (author)

  13. Nutritional characteristics and losses on fermentation of corn silage, harvested in different reproductive stages with different grain processing

    Directory of Open Access Journals (Sweden)

    Fabiano Marafon

    2015-04-01

    Full Text Available The aim of this study was evaluate the harvest of corn plant in different reproductive stages and different processing grain about losses and nutritive value of silages. Significant differences in the stage of harvest showed up in lower (P 0.05 results found for the R5 stage, which had an average loss of around 5.77%, demonstrating that silage harvested at R5 stage, allow greater dry matter recovery and hence greater savings for the farmer. Regarding the parameter of losses of crude protein, there were no significant differences for the effects of isolated or associated stages of harvesting and processing of grain in corn silage. Large differences can be perceived as the loss of neutral detergent fiber and loss of acid detergent fiber silage, justified by the increase in the levels of acid detergent fiber in the average share of 22.96% in the silage harvested at stage R3 and reduction in their concentration with an average of 4.60% for the R5 stage. No significant differences were observed (P <0.05 for the particle size as the different treatments, only significance being observed as the participation of whole grains in bulk, this ranging on average from 2.59% to 10.27% dry matter, respectively for stage R3 and R4-R5. In general, silage maize plant reproductive stage R5 provided smaller losses nutritious silage storage and greater accumulation of grains in bulk when compared to R3 stage.

  14. Methods of detection, species identification and quantification of processed animal proteins in feedingstuffs

    Directory of Open Access Journals (Sweden)

    Fumière O.

    2009-01-01

    Full Text Available The ban of processed animal proteins (PAPs in feed for farmed animals led to a significant reduction of the number of bovine spongiform encephalopathy cases. Presently, optical microscopy remains the only reference method for the detection of PAPs to be applied for official control as required by Commission Directive 2003/126/EC. The legislation also foresees that other methods may be applied in addition to classical microscopy, if – for instance – they provide more information about the origin of the animal constituents. Therefore, alternative and complementary techniques were developed as such or in combination. The most promising ones seem to be PCR (Polymerase Chain Reaction, near infrared microscopy and imaging, as well as immunology. Within the framework of a PAP ban regardless of its species origin (total feed ban, most of the studies were mainly focused on the ability of the techniques to detect the presence of PAPs at 0.1% (mass percentage of constituents of animal origin in feed as indicated as limit of detection in the official method protocol. A possible modification of the legislation requires that the techniques are also able to determine their species origin and to quantify them. The present paper gives a state of the art of the different methods.

  15. Selective Reproduction

    DEFF Research Database (Denmark)

    Svendsen, Mette N.

    2015-01-01

    This article employs a multi-species perspective in investigating how life's worth is negotiated in the field of neonatology in Denmark. It does so by comparing decision-making processes about human infants in the Danish neonatal intensive care unit with those associated with piglets who serve as...... expectations within linear or predictive time frames are key markers in both sites. Exploring selective reproductive processes across human infants and research piglets can help us uncover aspects of the cultural production of viability that we would not otherwise see or acknowledge....

  16. In Vivo Bioluminescent Imaging (BLI: Noninvasive Visualization and Interrogation of Biological Processes in Living Animals

    Directory of Open Access Journals (Sweden)

    Steven Ripp

    2010-12-01

    Full Text Available In vivo bioluminescent imaging (BLI is increasingly being utilized as a method for modern biological research. This process, which involves the noninvasive interrogation of living animals using light emitted from luciferase-expressing bioreporter cells, has been applied to study a wide range of biomolecular functions such as gene function, drug discovery and development, cellular trafficking, protein-protein interactions, and especially tumorigenesis, cancer treatment, and disease progression. This article will review the various bioreporter/biosensor integrations of BLI and discuss how BLI is being applied towards a new visual understanding of biological processes within the living organism.

  17. PRODUCTS OF PROCESSING OF RAPESEED IN FEEDING OF FARM ANIMALS AND POULTRY

    Directory of Open Access Journals (Sweden)

    Коnоnеnко S. I.

    2016-03-01

    Full Text Available In the current economic conditions of the import substitution, special importance is given to the search for new feed sources, methods of preparing them for feeding, the use of biologically active substances and enzymes. At the forefront of feed production is rape as breeding work with this culture has showed positive results. Currently, selectionists have bred yellow double-zero "00" varieties of rapeseeds free of erucic acid of "Canole" type, that have low glucosinolate level. The development of new and modern technology standards are required for preparation them for feeding, since they are fundamentally different from the previously used rapeseed varieties and have fewer restrictions for feeding to different types of farm animals and poultry. The article presents a fairly lengthy and reasoned review of the literature of a large number of authors on the topic, as well as given rapeseed market analysis, rational and advanced methods of preparing rapeseed processed products for feeding to young and adult animals. Much attention is paid to the use of a variety of biologically active substances and enzymes, which improve digestion and absorption of nutrients from rations with rapeseed processingproducts, increase productivity and reduce feed costs per unit of production. The use of processing products of rapeseed improves the profitability of livestock production. Feeding of rapeseedcake to cattle increases the protein content and volatile fatty acids in the rumen content, increases the number of infusoria and decreases ammonia levels. The inclusion of rape forage in diets of farm animals and poultry improves hematological parameters. Products of rapeseed processing of the varieties with low glucosinolatesa1re recommended for the rations of farm animals and poultry depending on the species, age and physiological state

  18. Making and Unmaking the Endangered in India (1880-Present: Understanding Animal-Criminal Processes

    Directory of Open Access Journals (Sweden)

    Varun Sharma

    2015-01-01

    Full Text Available The concerns of the present paper emerge from the single basic question of whether the available histories of the tiger are comprehensive enough to enable an understanding of how this nodular species comprises/contests the power dynamics of the present. Starting with this basic premise, this paper retells a series of events which go to clarify that a nuanced understanding of the manner in which a species serves certain political purposes is not possible by tracking the animal alone. A discourse on endangerment has beginnings in the body and being of species that are remarkably cut off from the tiger-the elephant, birds, and the rhino (and man if we might add-and develops with serious implications for power, resource appropriation, and criminality, over a period of time, before more directly recruiting the tiger itself. If we can refer to this as the intermittent making and unmaking of the endangered, it is by turning to the enunciations of Michel Foucault that we try to canvas a series of events that can be described as animal-criminal processes. The role of such processes in the construction of endangerment, the structuring of space, and shared ideas of man-animal relations is further discussed in this paper.

  19. Unique educational methods to improve the veterinary employment selection process for rural mixed-animal practices.

    Science.gov (United States)

    White, Brad J; Gwinner, Kevin P; Andrus, David M; Prince, J Bruce

    2007-01-01

    The rural mixed-animal veterinarian is a critical control point for safe, wholesome, affordable food production and security. The population of students entering food-animal practice is decreasing, and future shortages are likely. Veterinary practice owners will continue to struggle to find associates to fill open positions. Identifying and hiring the correct veterinarian for an open position is a challenging proposition for the rural practitioner. Kansas State University hosted a forum to facilitate the hiring process and provide education regarding the mechanism of an effective selection interview. A unique experiential technique known as "speed interviews" was used to facilitate communication between conference participants and to practice newly acquired skills. A survey of participants revealed similar viewpoints toward most job attributes. Veterinary students and prospective employers expressed realistic expectations of job requirements, salaries, and debt load. Students expressed willingness to work and desire to practice in the types of practices defined by the veterinarians. The symposium provided valuable insight for practitioners and students regarding the recruitment process. Appropriate and accurate representation at the time of job/associate selection is critical for long-term success and employee retention. The goal of the event was to provide a service to both prospective employers and students by offering education regarding the employment selection interview process and placing attendees in an environment rich with people who have complimentary goals. PMID:18287482

  20. Vertebrate Reproduction.

    Science.gov (United States)

    Kornbluth, Sally; Fissore, Rafael

    2015-10-01

    Vertebrate reproduction requires a myriad of precisely orchestrated events-in particular, the maternal production of oocytes, the paternal production of sperm, successful fertilization, and initiation of early embryonic cell divisions. These processes are governed by a host of signaling pathways. Protein kinase and phosphatase signaling pathways involving Mos, CDK1, RSK, and PP2A regulate meiosis during maturation of the oocyte. Steroid signals-specifically testosterone-regulate spermatogenesis, as does signaling by G-protein-coupled hormone receptors. Finally, calcium signaling is essential for both sperm motility and fertilization. Altogether, this signaling symphony ensures the production of viable offspring, offering a chance of genetic immortality. PMID:26430215

  1. Advances in reproductive biotechnologies

    Science.gov (United States)

    Choudhary, K. K.; Kavya, K. M.; Jerome, A.; Sharma, R. K.

    2016-01-01

    In recent times, reproductive biotechnologies have emerged and started to replace the conventional techniques. It is noteworthy that for sustained livestock productivity, it is imperative to start using these techniques for facing the increasing challenges for productivity, reproduction and health with impending environment conditions. These recent biotechniques, both in male and female, have revolutionized and opened avenues for studying and manipulating the reproductive process both in vitro and in vivo in various livestock species for improving tis efficiency. This review attempts to highlight pros and cons, on the recent developments in reproductive biotechnologies, both in male and female in livestock species. PMID:27182135

  2. Reproductive and health assessment of fathead minnows (Pimephales promelas) inhabiting a pond containing oil sands process-affected water

    Energy Technology Data Exchange (ETDEWEB)

    Kavanagh, Richard J., E-mail: rkavanag@uoguelph.ca [Department of Integrative Biology, University of Guelph, Guelph, ON, Canada N1G 2W1 (Canada); Frank, Richard A.; Solomon, Keith R. [Centre for Toxicology, University of Guelph, Guelph, ON, Canada N1G 2W1 (Canada); Van Der Kraak, Glen [Department of Integrative Biology, University of Guelph, Guelph, ON, Canada N1G 2W1 (Canada)

    2013-04-15

    Highlights: ► Fish were collected from a pond containing oil sands process-affected water (OSPW). ► They were compared to fish from two reference sites within the oil sands region. ► Differences in GSIs and tubercle numbers were observed in fish from the OSPW pond. ► Opercula, gills, and 11-KT concentrations also differed in fish from the OSPW pond. ► Black spot and tapeworms were not observed in any of the fish from the OSPW pond. -- Abstract: Previous laboratory based studies have shown that oil sands process-affected waters (OSPWs) containing high concentrations of naphthenic acids (>25 mg/l) have adverse effects on the reproductive physiology of fish. The purpose of this study was to assess the reproductive development and health of a wild population of fathead minnows (Pimephales promelas) inhabiting an OSPW pond that has moderate concentrations of naphthenic acids (∼10 mg/l). Fathead minnows were collected at various times during the period of 2006 through 2008 from Demonstration Pond (OSPW) located at Syncrude Canada Ltd., and two reference sites, Beaver Creek reservoir and Poplar Creek reservoir, which are all north of Fort McMurray, AB, Canada. Condition factor, gill histopathology, gonadosomatic indices, liver somatic indices, male secondary sexual characteristics, and plasma sex steroids were examined. Depending on the time of year that fathead minnows were collected, there were differences in the condition factor, gonadosomatic indices, liver somatic indices, and secondary sexual characteristics of fathead minnows (in males) from Demonstration Pond when compared to the fathead minnows from the reference sites. In comparison to reference fish, lower concentrations of 11-ketotestosterone were measured in the plasma of male fathead minnows collected from Demonstration Pond in June 2006 and July 2007. Black spot disease and Ligula intestinalis were prevalent in fathead minnows from the reference sites but were not observed in fathead minnows

  3. Reproductive and health assessment of fathead minnows (Pimephales promelas) inhabiting a pond containing oil sands process-affected water

    International Nuclear Information System (INIS)

    Highlights: ► Fish were collected from a pond containing oil sands process-affected water (OSPW). ► They were compared to fish from two reference sites within the oil sands region. ► Differences in GSIs and tubercle numbers were observed in fish from the OSPW pond. ► Opercula, gills, and 11-KT concentrations also differed in fish from the OSPW pond. ► Black spot and tapeworms were not observed in any of the fish from the OSPW pond. -- Abstract: Previous laboratory based studies have shown that oil sands process-affected waters (OSPWs) containing high concentrations of naphthenic acids (>25 mg/l) have adverse effects on the reproductive physiology of fish. The purpose of this study was to assess the reproductive development and health of a wild population of fathead minnows (Pimephales promelas) inhabiting an OSPW pond that has moderate concentrations of naphthenic acids (∼10 mg/l). Fathead minnows were collected at various times during the period of 2006 through 2008 from Demonstration Pond (OSPW) located at Syncrude Canada Ltd., and two reference sites, Beaver Creek reservoir and Poplar Creek reservoir, which are all north of Fort McMurray, AB, Canada. Condition factor, gill histopathology, gonadosomatic indices, liver somatic indices, male secondary sexual characteristics, and plasma sex steroids were examined. Depending on the time of year that fathead minnows were collected, there were differences in the condition factor, gonadosomatic indices, liver somatic indices, and secondary sexual characteristics of fathead minnows (in males) from Demonstration Pond when compared to the fathead minnows from the reference sites. In comparison to reference fish, lower concentrations of 11-ketotestosterone were measured in the plasma of male fathead minnows collected from Demonstration Pond in June 2006 and July 2007. Black spot disease and Ligula intestinalis were prevalent in fathead minnows from the reference sites but were not observed in fathead minnows

  4. Reproductive biotechnologies in Swedish male alpacas

    OpenAIRE

    Abraham, Maria Celina

    2016-01-01

    Alpacas have become more popular during the last decades. The herds have been built up by importing live animals since reproductive biotechnologies, for example artificial insemination and semen preservation, are not well-developed in this species. A major problem is the viscosity of the seminal plasma which hinders processing or evaluation of the semen. Enzymes have been used to deal with the viscous seminal plasma but they may damage spermatozoa or render them incapable of fertilization. Th...

  5. Bioconversion of Radiation Processed Dried Tomato Pomace to High Protein Animal Fee

    International Nuclear Information System (INIS)

    The increasing expansion of agro-industrial activity over the last 50 years has led to the accumulation of a large quantity of organic residues all over the world that they have become a threat to the environment. Bioconversion of these wastes seems to be a practical and promising alternative for increasing their nutritional value, transforming them into animal feed and thus producing a value added product. Radiation processing has the capability to reduce or eliminate pathogenic bacteria, insects and parasites, thereby increasing the utilization and sustainable management of waste organic matter from food production and processing while contributing to improve food quality and reducing the environmental impact of the wastes. The main purpose of this study was to evaluate the effect of radiation treatment at 25 kGy and fermentation process by Aspergillus niger, on crude and soluble protein, amino acid profile, available lysine and in vitro digestibility of dried tomato pomace (DTP), the by-product of the tomato canning industry. The study has also, investigated the effect of supplementation of 30% of raw or processed DTP meal in food of male Albino rats for six weeks on body and liver weight evaluation and the effect on blood lipid pattern. The work concluded that the combination between the irradiation of DTP at 25 kGy and fermentation process has increased the nutritional value of treated DTP meal and improved the plasma and liver lipid pattern of rats. Therefore, the combination treatment has beneficial effects on recycling of DTP and permits it to be included in monogastric animals' food without any health hazard or nutritional problem

  6. The Optimum Mesophilic Temperature of Batch Process Biogas Production from Animal-based Wastes

    Directory of Open Access Journals (Sweden)

    Osita Obineche Obiukwu

    2014-10-01

    Full Text Available The optimum mesophilic temperature of biogas production from blends The optimum temperature of biogas production from blends of animal-based wastes was determined under controlled heat supply to the digester in a batch digestion process. Cow Dung (CD and Poultry Droppings (PD were blended in the ratio of CD: PD: 1:3. The digester was operated at average ambient temperature of 30°C as baseline. Biogas production from the waste blends was monitored under the temperatures of 32 to 45°C. Results obtained indicate maximum cumulative gas yield was observed at the temperature of 40°C. The 40°C temperature gave the highest biogas yield of 2685 mL followed by the 35°C temperature with the cumulative yield of 2535 mL. The ambient temperature of 30°C had the least cumulative biogas yield of 185 mL. These results indicate that increased and steady biogas production can be achieved under the optimum mesophilic temperature of 40°C when these animal-based wastes are digested in batch digestion process.

  7. Modeling unobserved sources of heterogeneity in animal abundance using a Dirichlet process prior

    Science.gov (United States)

    Dorazio, R.M.; Mukherjee, B.; Zhang, L.; Ghosh, M.; Jelks, H.L.; Jordan, F.

    2008-01-01

    In surveys of natural populations of animals, a sampling protocol is often spatially replicated to collect a representative sample of the population. In these surveys, differences in abundance of animals among sample locations may induce spatial heterogeneity in the counts associated with a particular sampling protocol. For some species, the sources of heterogeneity in abundance may be unknown or unmeasurable, leading one to specify the variation in abundance among sample locations stochastically. However, choosing a parametric model for the distribution of unmeasured heterogeneity is potentially subject to error and can have profound effects on predictions of abundance at unsampled locations. In this article, we develop an alternative approach wherein a Dirichlet process prior is assumed for the distribution of latent abundances. This approach allows for uncertainty in model specification and for natural clustering in the distribution of abundances in a data-adaptive way. We apply this approach in an analysis of counts based on removal samples of an endangered fish species, the Okaloosa darter. Results of our data analysis and simulation studies suggest that our implementation of the Dirichlet process prior has several attractive features not shared by conventional, fully parametric alternatives. ?? 2008, The International Biometric Society.

  8. Immunoassay for the Detection of Animal Central Nervous Tissue in Processed Meat and Feed Products.

    Science.gov (United States)

    Rao, Qinchun; Richt, Juergen A; Hsieh, Yun-Hwa Peggy

    2016-05-11

    An indirect competitive enzyme-linked immunosorbent assay (icELISA) based on the detection of the thermal-stable central nervous tissue (CNT) marker protein, myelin basic protein (MBP), was developed to detect animal CNT in processed meat and feedstuffs. Two meat samples (cooked at 100 °C for 30 min and autoclaved at 133 °C for 20 min) of bovine brain in beef and two feed samples (bovine brain meal in beef meal and in soybean meal) were prepared at levels of 0.0008, 0.0031, 0.0063, 0.0125, 0.025, 0.05, 0.1, 0.2, 0.4, 0.8, and 1.6%. An anti-MBP monoclonal antibody (mAb3E3) was produced using the hybridoma technique and characterized using Western blot. The optimized icELISA was CNT-specific without cross-reactivity with either meat (beef and pork) or soybean meal samples and had low intra-assay (%CV ≤ 3.5) and interassay variability (%CV ≤ 3.3), with low detection limits for bovine MBP (6.4 ppb) and bovine CNT spiked in both meat (0.05%) and feed (0.0125%) samples. This assay is therefore suitable for the quantitative detection of trace amounts of contaminated animal CNT in processed food and feed products. PMID:27109117

  9. Concise review: transmissible animal tumors as models of the cancer stem-cell process.

    Science.gov (United States)

    O'Neill, Iain D

    2011-12-01

    Tasmanian devil facial tumor disease (DFTD) and canine transmissible venereal tumor (CTVT) are highly unusual cancers capable of being transmitted between animals as an allograft. The concept that these tumors represent a cancer stem-cell process has never been formally evaluated. For each, evidence of self-renewal is found in the natural history of these tumors in the wild, tumor initiation in recipient animals, and serial transplantation studies. Additional data for stem-cell-specific genes and markers in DFTD also exist. Although both tumor types manifest as undifferentiated cancers, immunocytohistochemistry supports a histiocytic phenotype for CTVT and a neural crest origin, possibly a Schwann-cell phenotype, for DFTD. In these data, differential expression of lineage markers is seen which may suggest some capacity for differentiation toward a heterogeneous variety of cell types. It is proposed that DFTD and CTVT may represent and may serve as models of the cancer stem-cell process, but formal investigation is required to clarify this. Appreciation of any such role may act as a stimulus to ongoing research in the pathology of DFTD and CTVT, including further characterization of their origin and phenotype and possible therapeutic approaches. Additionally, they may provide valuable models for future studies of their analogous human cancers, including any putative CSC component. PMID:21956952

  10. A nutribusiness strategy for processing and marketing animal-source foods for children.

    Science.gov (United States)

    Mills, Edward W; Seetharaman, Koushik; Maretzki, Audrey N

    2007-04-01

    Nutritional benefits of animal source foods in the diets of children in developing countries indicate a need to increase the availability of such foods to young children. A nutribusiness strategy based on a dried meat and starch product could be used to increase children's access to such foods. The "Chiparoo" was developed at The Pennsylvania State University with this objective in mind. Plant-based and meat ingredients of the Chiparoo are chosen based on regional availability and cultural acceptability. Chiparoo processing procedures, including solar drying, are designed to ensure product safety and to provide product properties that allow them to be eaten as a snack or crumbled into a weaning porridge. Continued work is needed to develop formulation and processing variations that accommodate the needs of cultures around the world. PMID:17374690

  11. Pilot scale study - processing of palm empty fruit bunch into animal feed at sterifeed pilot plant

    International Nuclear Information System (INIS)

    Fermented oil palm empty fruit bunch, now known as 'Sterifeed' has been characterized by physico-chemical properties. It has also been proven to have an improved digestibility (by in vitro and in-vivo test) over the original material. The remaining important aspect of feed to be examined is the long term effect of feeding this material to animals. The size of fermentation media bags used was 0.5-1 kg/bag. In the large scale production of these materials, the numbers of bags were increased. The production at pilot scale level reinvestigated the basic processing parameters for the 1 kg/bag media and also performed a trial run for different sizes of bags. These include: 1) investigation on the growth of fungi on fermentation media subjected to different treatment times and the non treated media, 2) evaluation of the processing rate, 3) trial run processing of 25-50 MT oil palm EFB into feed, and 4) processing of different sizes of bags

  12. Environmental lighting alters the infection process in an animal model of AIDS.

    Science.gov (United States)

    McEachron, D L; Tumas, K M; Blank, K J; Prystowsky, M B

    1995-08-01

    In this study, we examined the effects of altered environmental lighting on the infection process of a murine leukemia virus, E-55(+), which induces a thymic lymphoma/leukemia in 100% of BALB.K mice inoculated as adults. One to two weeks after inoculation, high levels of proviral DNA are usually found. This is followed by an asymptomatic period of many weeks during which proviral DNA becomes essentially undetectable. Leukemia develops approximately 28 weeks postinoculation. In this experiment, one group of mice was exposed a consistent 10L: 14D cycle while a second was maintained in constant light (LL). A third group was exposed to a rotating cycle characterized by phase shifting a 10L: 14D cycle every three 24-h days (rLD). All cycles began 2 weeks prior to inoculation and were maintained thereafter. Animals were sacrificed at 1, 5, 10, and 15 weeks, and hematopoietic tissue was examined for proviral DNA content. At 1 week, LL- and rLD-exposed animals showed considerably less proviral DNA in bone marrow and spleen compared with controls. At 15 weeks, thymuses from controls were showing signs of infection whereas tissue from LL and rLD mice remained at background levels. We conclude that environmental lighting does alter the infective pattern displayed by this retrovirus, although whether this effect is mediated by changes in the target stem cells or through immunoenhancement has not yet been determined. PMID:7675882

  13. Reproductive health financing in Kenya: an analysis of national commitments, donor assistance, and the resources tracking process

    NARCIS (Netherlands)

    Sidze, E.M.; Pradhan, J.; Beekink, E.; Maina, T.M.; Maina, B.W.

    2013-01-01

    Understanding the flow of resources at the country level to reproductive health is essential for effective financing of this key component of health. This paper gives a comprehensive picture of the allocation of resources for reproductive health in Kenya and the challenges faced in the resource-trac

  14. Re/Production of science process skills and a scientific ethos in an early childhood classroom

    Science.gov (United States)

    Kirch, Susan A.

    2007-10-01

    Many educators and researchers are convinced that age limits what students can learn and achieve in science. Elementary school curricula focus on isolated process skills under the faulty assumption that young students are not capable of combining the process skills and content knowledge necessary for reasoning scientifically. In the present study, I demonstrate that many process skills are produced in conversations between second grade students and between these students and their teachers, including: questioning, hypothesis formation, experimental design, identifying relevant evidence, critical analysis of hypotheses and predictions, hypothesis reconstruction, and variable identification. Through conversation analysis I show that most classroom community members adopted the role of skeptic at some time, but there was a strong tendency to defer to authoritative sources when resolving debates. This latter observation led to further investigation of when and how authoritative sources were consulted and used, and when and how a skeptical stance was taken. I show that, as students used science process skills and interacted with each other and teacher-mediators, community practices, values, and mores were shaped and an ethos of science began to emerge. It is my contention that this ethos often emerges unconsciously as part of the community's dynamic set of rules and schema. Teachers who are attuned to the tension between open-mindedness and skepticism, and how they and their students cope with this dialectic, however, can actively shape the scientific ethos of their classroom community.

  15. Bituminization of simulated waste, spent resins, evaporator concentrates and animal ashes by extrusion process

    International Nuclear Information System (INIS)

    The results of the study of bituminization of simulated radwaste - spennt ion-exchange resins, borate evaporator/concentrates and animal ashes, are presented and discussed. Distilled and oxidizer bitumen were used. Characterization of the crude material and simulated wastes-bitumen mixtures of varying weigt composition (30, 40, 50, 60% by weight of dry waste material) was carried out. The asphaltene and parafin contents in the bitumens were also determined. Some additives and were used with an aim to improve the characteristcs of solidified wastes. For leaching studies, granular ion-exchange resins were with Cs - 134 and mixtures of resin-bitumen were prepared. The leaching studies were executed using the IAEA recommendation and the ISO method. A conventional screw-extruder, common in plastic industry, was used determine operational parameters and process difficulties. Mixtures of resin-bitumen and evaporator concentrate-bitumen obtained from differents operational conditions were characterized. (Author)

  16. Applications of hormone radioimmunoassays on studies of environment and reproduction interactions in large ruminants

    International Nuclear Information System (INIS)

    The effects of environment on the reproductive processes of female cattle are described. Variation in fertility responses is partitioned into environmental and genetic effects. Environmental effects are defined as all effects that are non-genetic, and emphasis is placed on quantitation of the climatic measurements (e.g. maximum environmental temperature) associated with reproductive performance. Sensitivities of various reproductive events to thermal stress are defined and include such responses as reproductive behaviour, hormonal balance, alterations in uterine blood flow, embryonic death, conceptus development, placental function and restoration of the postpartum reproductive function. Several management strategies are discussed to improve animal productivity, including environmental modification, reproductive management and evidence of genetic adaptation to local environments through selection. (author)

  17. Animal welfare evaluation at a slaughterhouse for heavy pigs intended for processing

    OpenAIRE

    Roberta Stocchi; Nicholas Aconiti Mandolini; Maria Marinsalti; Natalina Cammertoni; Anna Rita Loschi; Stefano Rea

    2014-01-01

    The Council Regulation (EC) No. 1099/2009 requires slaughterhouse managers to implement specific standard operating procedures for all pre-slaughter stages considered at risk, aimed at achieving adequate levels of animal welfare. This survey was aimed at testing the applicability to an abattoir for heavy pigs of an assessment system of animal welfare through animal-based measures. In the monitoring of handling operations, the number of animals fallen/slipped and prodded, and that of vocalisin...

  18. Framework for hyperspectral image processing and quantification for cancer detection during animal tumor surgery

    Science.gov (United States)

    Lu, Guolan; Wang, Dongsheng; Qin, Xulei; Halig, Luma; Muller, Susan; Zhang, Hongzheng; Chen, Amy; Pogue, Brian W.; Chen, Zhuo Georgia; Fei, Baowei

    2015-12-01

    Hyperspectral imaging (HSI) is an imaging modality that holds strong potential for rapid cancer detection during image-guided surgery. But the data from HSI often needs to be processed appropriately in order to extract the maximum useful information that differentiates cancer from normal tissue. We proposed a framework for hyperspectral image processing and quantification, which includes a set of steps including image preprocessing, glare removal, feature extraction, and ultimately image classification. The framework has been tested on images from mice with head and neck cancer, using spectra from 450- to 900-nm wavelength. The image analysis computed Fourier coefficients, normalized reflectance, mean, and spectral derivatives for improved accuracy. The experimental results demonstrated the feasibility of the hyperspectral image processing and quantification framework for cancer detection during animal tumor surgery, in a challenging setting where sensitivity can be low due to a modest number of features present, but potential for fast image classification can be high. This HSI approach may have potential application in tumor margin assessment during image-guided surgery, where speed of assessment may be the dominant factor.

  19. Collection and processing of plant, animal and soil samples from Bikini, Enewetak and Rongelap Atolls

    International Nuclear Information System (INIS)

    The United States used the Marshall Islands for its nuclear weapons program testing site from 1946 to 1958. The BRAVO test was detonated at Bikini Atoll on March 1, 1954. Due to shifting wind conditions at the time of the nuclear detonation, many of the surrounding Atolls became contaminated with fallout (radionuclides carried by the wind currents). Lawrence Livermore National Laboratory's (LLNL) Marshall Islands Project has been responsible for the collecting, processing, and analyzing of food crops, vegetation, soil, water, animals, and marine species to characterize the radionuclides in the environment, and to estimate dose at atolls that may have been contaminated. Tropical agriculture experiments reducing the uptake of 137Cs have been conducted on Bikini Atoll. The Marshall Islands field team and laboratory processing team play an important role in the overall scheme of the Marshall Islands Dose Assessment and Radioecology Project. This report gives a general description of the Marshall Islands field sampling and laboratory processing procedures currently used by our staff

  20. Collection and processing of plant, animal and soil samples from Bikini, Enewetak and Rongelap Atolls

    Energy Technology Data Exchange (ETDEWEB)

    Stuart, M.L.

    1995-09-01

    The United States used the Marshall Islands for its nuclear weapons program testing site from 1946 to 1958. The BRAVO test was detonated at Bikini Atoll on March 1, 1954. Due to shifting wind conditions at the time of the nuclear detonation, many of the surrounding Atolls became contaminated with fallout (radionuclides carried by the wind currents). Lawrence Livermore National Laboratory`s (LLNL) Marshall Islands Project has been responsible for the collecting, processing, and analyzing of food crops, vegetation, soil, water, animals, and marine species to characterize the radionuclides in the environment, and to estimate dose at atolls that may have been contaminated. Tropical agriculture experiments reducing the uptake of {sup 137}Cs have been conducted on Bikini Atoll. The Marshall Islands field team and laboratory processing team play an important role in the overall scheme of the Marshall Islands Dose Assessment and Radioecology Project. This report gives a general description of the Marshall Islands field sampling and laboratory processing procedures currently used by our staff.

  1. Mass cultivation of microalgae on animal wastewater: a sequential two-stage cultivation process for energy crop and omega-3-rich animal feed production.

    Science.gov (United States)

    Zhou, Wenguang; Hu, Bing; Li, Yecong; Min, Min; Mohr, Michael; Du, Zhenyi; Chen, Paul; Ruan, Roger

    2012-09-01

    In this study, 97 microalgal strains purchased from algae bank and 50 microalgal strains isolated from local waters in Minnesota were screened for their adaptability growing on a 20-fold diluted digested swine manure wastewater (DSMW). A pool of candidate strains well adapted to the DSMW was established through a high-throughput screening process. Two top-performing facultative heterotrophic strains with high growth rate (0.536 day(-1) for UMN 271 and 0.433 day(-1) for UMN 231) and one strain with high omega-3 unsaturated fatty acid (EPA, 3.75 % of total fatty acids for UMN 231) were selected. Subsequently, a sequential two-stage mixo-photoautotrophic culture strategy was developed for biofuel and animal feed production as well as simultaneous swine wastewater treatment using above two strains. The maximal biomass concentration and lipid content at the first and second stages reached 2.03 g/L and 23.0 %, and 0.83 g/L and 19.0 % for UMN 271 and UMN 231, respectively. The maximal nutrient removals for total phosphorus and ammonia after second-stage cultivation were 100 and 89.46 %, respectively. The experiments showed that this sequential two-stage cultivation process has great potential for economically viable and environmentally friendly production of both renewable biofuel and high-value animal feed and at the same time for animal wastewater treatment. PMID:22798164

  2. The Cerebellum in Emotional Processing: Evidence from Human and Non-Human Animals

    Directory of Open Access Journals (Sweden)

    Wanda M. Snow

    2014-06-01

    Full Text Available The notion that the cerebellum is a central regulator of motor function is undisputed. There exists, however, considerable literature to document a similarly vital role for the cerebellum in the regulation of various non-motor domains, including emotion. Research from numerous avenues of investigation (i.e., neurophysiological, behavioural, electrophysiological, imagining, lesion, and clinical studies have documented the importance of the cerebellum, in particular, the vermis, in affective processing that appears preserved across species. The cerebellum possesses a distinct laminar arrangement and highly organized neuronal circuitry. Moreover, the cerebellum forms reciprocal connections with several brain regions implicated in diverse functional domains, including motor, sensory, and emotional processing. It has been argued that these unique neuroanatomical features afford the cerebellum with the capacity to integrate information about an organism, its environment, and its place within the environment such that it can respond in an appropriate, coordinated fashion, with such theories extending to the regulation of emotion. This review puts our current understanding of the cerebellum and its role in behaviour in historical perspective, presents an overview of the neuroanatomical and functional organization of the cerebellum, and reviews the literature describing the involvement of the cerebellum in emotional regulation in both humans and non-human animals. In summary, this review discusses the importance of the functional connectivity of the cerebellum with various brain regions in the ability of the cerebellum to effectively regulate emotional behaviour.

  3. Reproduction of post-weaning multi-systemic wasting syndrome in an animal disease model as a tool for vaccine testing under controlled conditions.

    Science.gov (United States)

    McKillen, John; McNair, Irene; Lagan, Paula; McKay, Karen; McClintock, Julie; Casement, Veronica; Charreyre, Catherine; Allan, Gordon

    2016-04-01

    Snatch farrowed, colostrum deprived piglets were inoculated with different combinations of porcine circovirus 2, porcine parvovirus and Erysipelothrix rhusiopathiae candidate vaccines. 10 piglets were mock-vaccinated. Following virus challenge with a combined porcine circovirus 2/porcine parvovirus inoculum, all animals were monitored and samples taken for serology, immunohistochemistry and qPCR. At 24dpc all non-vaccinated animals remaining were exhibiting signs of post-weaning multi-systemic wasting syndrome which was confirmed by laboratory analysis. Details of the study, analysis of samples and performance of the candidate vaccines are described. PMID:27033924

  4. Molecular characterization and analysis of a putative 5-HT receptor involved in reproduction process of the pearl oyster Pinctada fucata.

    Science.gov (United States)

    Wang, Qi; He, Maoxian

    2014-08-01

    5-HT (5-hydroxytryptamine; serotonin) has been linked to a variety of biological roles including gonad maturation and sequential spawning in bivalve molluscs. To gain a better understanding of the effects of 5-HT on developmental regulation in the pearl oyster Pinctada fucata, the isolation, cloning, and expression of the 5-HT receptor was investigated in this study. A full-length cDNA (2541 bp) encoding a putative 5-HT receptor (5-HTpf) of 471 amino acids was isolated from the ovary of the pearl oyster. It shared 71% and 51% homology, respectively, with the Crassostrea gigas 5-HT receptor and the Aplysia californica 5-HT1ap. The 5-HTpf sequence possessed the typical characteristics of seven transmembrane domains and a long third inner loop. Phylogenetic analysis also indicated that 5-HTpf was classified into the 5-HT1 subtype together with other invertebrate 5-HT1 receptors. Quantitative RT-PCR showed that 5-HTpf is widely expressed in all tissues tested, is involved in the gametogenesis cycle, embryonic and larval development stages, and expression is induced by E2 in ovarian tissues. These results suggest that 5-HTpf is involved in the reproductive process, specifically in the induction of oocyte maturation and spawning of P. fucata. PMID:24852353

  5. ASSESSMENT OF LITHIUM USING THE IEHR EVALUATIVE PROCESS FOR ASSESSING HUMAN DEVELOPMENTAL AND REPRODUCTIVE TOXICITY OF AGENTS

    Science.gov (United States)

    This document presents an evaluation of the reproductive and developmental effects of lithium and reviews toxicologic information on several specific lithium salts: ithium carbonate, lithium chloride, lithium citrate, and lithium hypochlorite. ithium (Li), an alkali metal, is a n...

  6. Nutrition and reproduction are key parameters in the interaction process leading to Crassostrea gigas oyster summer mortality in France

    OpenAIRE

    Samain, Jean-francois; Degremont, Lionel; Soletchnik, Patrick; Ropert, Michel; Bedier, Edouard; Mazurie, Joseph; Martin, Jean-Louis; Moal, Jeanne; Mathieu, Michel; Pouvreau, Stephane; Lambert, Christophe; Escoubas, Jean-Michel; Nicolas, Jean-Louis; Le Roux, Frédérique; Renault, Tristan

    2006-01-01

    Complex interactions between oyster, environment and pathogens were observed during the MOREST (2001-2005) project on summer mortality events of Crassostrea gigas oysters in France. The talk will show how nutrition level increasing reproductive intensity generates a risk for pathogen infection under synergistic effect of temperature and stress. Moreover, a genetic component is associated to specific reproductive performances and spawning behaviour. To better understand origin of such resistan...

  7. Evaluation of the Growth Process of Infants Conceived by Assisted Reproductive Techniques at Royan Institute from Birth to 9 Months

    Directory of Open Access Journals (Sweden)

    Mohammad-Reza Nateghi

    2011-12-01

    Full Text Available Objective: Due to recent scientific progress in assisted reproductive techniques (ART, infertile couples can now become fertile. Thus, a number of infants in our country are the results of these costly interventions. This study has been undertaken to evaluate the physical growth process of different methods of ART infants by standard growth charts from birth until nine months of age.Methods: This was a descriptive cross-sectional study of 333 infants conceived through ART [intracytoplasmic sperm injection (ICSI and in vitro fertilization (IVF] at Royan Institute. A sequential, non-random sampling method in a period of 22 months was used. Their growth was assessed by measuring infants weight, height and head circumference, and physical examination. The growth patterns were calculated by recording the values in standard growth charts. The final analysis was done with SPSS version 16 and by using Chi-square test.Findings: In comparison with growth charts, the weights of one-third of the infants were less than two standard deviations (SD at birth and one-fourth had head circumference less than three SD at birth. Low birth weight (LBW infants were six times more than infants of normal population. From birth to six months of age, growth abnormalities were seen in a substantial number of infants. However, at nine months of age, there was no significant difference observed between infants conceived by different methods of ART (IVF and ICSI.Conclusion: Multiple births are the most important confounding factor impacting the growth process of ART infants. Multiple pregnancies can lead to low birth weight, height and head circumference, and growth abnormalities up to six months of age. This abnormality improves by increasing age of the infants.

  8. IMPAIRED PROCESSING IN THE PRIMARY AUDITORY CORTEX OF AN ANIMAL MODEL OF AUTISM

    Directory of Open Access Journals (Sweden)

    Renata eAnomal

    2015-11-01

    Full Text Available Autism is a neurodevelopmental disorder clinically characterized by deficits in communication, lack of social interaction and, repetitive behaviors with restricted interests. A number of studies have reported that sensory perception abnormalities are common in autistic individuals and might contribute to the complex behavioral symptoms of the disorder. In this context, hearing incongruence is particularly prevalent. Considering that some of this abnormal processing might stem from the unbalance of inhibitory and excitatory drives in brain circuitries, we used an animal model of autism induced by valproic acid (VPA during pregnancy in order to investigate the tonotopic organization of the primary auditory cortex (AI and its local inhibitory circuitry. Our results show that VPA rats have distorted primary auditory maps with over-representation of high frequencies, broadly tuned receptive fields and higher sound intensity thresholds as compared to controls. However, we did not detect differences in the number of parvalbumin-positive interneurons in AI of VPA and control rats. Altogether our findings show that neurophysiological impairments of hearing perception in this autism model occur independently of alterations in the number of parvalbumin-expressing interneurons. These data support the notion that fine circuit alterations, rather than gross cellular modification, could lead to neurophysiological changes in the autistic brain.

  9. Effect of acid deposition on soil animals and microorganisms: influence on structures and processes

    International Nuclear Information System (INIS)

    Principal effects of acid stress on the soil subsystem are increase or decrease in faunal and microfloral populations, changes in species assemblages and overall reductions in several soil microbiological processes. Little is known about the effects on nitrogen transformation (ammonification, nitrification, denitrification). Some possible but hypothetical scenarios for the effect of acidification stress on the forest ecosystem level are: (1) Inhibition of decomposition leads to an accumulation of litter. Immission and other disturbances may lead to humus disintegration and nitrate leaching; (2) Inhibition of mineralization reduces the availability of plant nutrients; (3) Decrease of the microfauna may cause disturbances of matter microcycling in the root zone; (4) Increase of the mesofauna may enhance the gracing pressure on mycorrhizal mycelia for even fine roots; (5) Decrease of the macrofauna (especially earthworms) lead to less bioturbation which impairs the buffer capacity of the litter and topsoil. A general outcome of liming experiments is stimulation of decomposition and mineralization: (1) Increased in nutrient arailability could lead to increased productivityin nutrient limited stands; (2) More irregular effects of animals on microbial activity may result in low stability of the soil-litter system and high liability to perturbations. (orig./vhe)

  10. Gene delivery process in a single animal cell after femtosecond laser microinjection

    International Nuclear Information System (INIS)

    Microinjection of extracellular molecules into a single animal cell was performed by an amplified femtosecond laser irradiation. When a single-shot laser pulse was focused on the plasma membrane of a single fibroblast from the mouse cell line NIH3T3 with a high-numerical aperture objective lens, a transient hole with a diameter of 1 μm was formed. The delivery process of extracellular molecules immediately after the hole formation was monitored by a fluorescence staining with fluoresceinisothiocyanate-dextran (FITC-dextran). Then the gene expression was confirmed using a DNA plasmid of an enhanced green fluorescent protein (EGFP). The gene expression was observed when the laser pulse was focused first on the cellular membrane and then on the nuclear membrane, while the gene was not expressed when the laser was focused only on the cellular membrane. On the basis of these results, the efficiency of gene delivery by the femtosecond laser microinjection and the subsequent gene expression were clarified.

  11. Using Ants, Animal Behavior & the Learning Cycle to Investigate Scientific Processes

    Science.gov (United States)

    Ligon, Russell A.; Dolezal, Adam G.; Hicks, Michael R.; Butler, Michael W.; Morehouse, Nathan I.; Ganesh, Tirupalavanam G.

    2014-01-01

    The behavior of animals is an intrinsically fascinating topic for students from a wide array of backgrounds. We describe a learning experience using animal behavior that we created for middle school students as part of a graduate-student outreach program, Graduate Partners in Science Education, at Arizona State University in collaboration with a…

  12. Effects of Animation's Speed of Presentation on Perceptual Processing and Learning

    Science.gov (United States)

    Meyer, Katja; Rasch, Thorsten; Schnotz, Wolfgang

    2010-01-01

    Animations presented at different speed are assumed to differentially interact with learners' perception and cognition due to the constraints imposed by learners' limited sensitivity to incoming dynamic information. To investigate the effects of high and low presentation speed of animation, two studies were conducted. In Study 1, participants were…

  13. Potential application of electronic nose in processed animal proteins (PAP detection in feedstuffs

    Directory of Open Access Journals (Sweden)

    Dell'Orto V.

    2004-01-01

    Full Text Available Electronic nose and olfactometry techniques represent a modern analytical approach in food industry since they could potentially improve quality and safety of food processing. The aim of this study was to evaluate possible application of electronic nose in PA P detection and recognition in feed. For this purpose 6 reference feedstuffs (CRA-W / UE STRAT F E E D Project were used. The basis of the test samples was a compound feed for bovine fortified with processed animal proteins ( PAP consisting of meat and bone meal (MBM and/or fish meal at different concentrations. Each feed sample was tested in glass vials and the odour profile was determined by the ten MOS (metal oxide semi-conductor sensors of the electronic nose. Ten different descriptors, representing each ten sensors of electronic nose, were used to characterise the odour of each sample. In the present study, electronic nose was able to discriminate the blank sample from all other samples containing PA P ( M B M , fish meal or both. Samples containing either 0.5% of MBM or 5% of fish meal were identified, while samples containing a high fish meal content (5% associated with a low MBM content (0.5% were not discriminated from samples containing solely fish meal at that same high level (5%. This latter indicates that probably the high fish meal level, in samples containing both MBM and fish meal, tended to mask MBM odour. It was also evident that two odour descriptors were enough to explain 72.12% of total variability in odour pattern. In view of these results, it could be suggested that electronic nose and olfactometry techniques can provide an interesting approach for screening raw materials in feed industry, even though further studies using a wider set of samples are needed.

  14. Understanding disease processes in multiple sclerosis through magnetic resonance imaging studies in animal models

    Directory of Open Access Journals (Sweden)

    Nabeela Nathoo

    2014-01-01

    Full Text Available There are exciting new advances in multiple sclerosis (MS resulting in a growing understanding of both the complexity of the disorder and the relative involvement of grey matter, white matter and inflammation. Increasing need for preclinical imaging is anticipated, as animal models provide insights into the pathophysiology of the disease. Magnetic resonance (MR is the key imaging tool used to diagnose and to monitor disease progression in MS, and thus will be a cornerstone for future research. Although gadolinium-enhancing and T2 lesions on MRI have been useful for detecting MS pathology, they are not correlative of disability. Therefore, new MRI methods are needed. Such methods require validation in animal models. The increasing necessity for MRI of animal models makes it critical and timely to understand what research has been conducted in this area and what potential there is for use of MRI in preclinical models of MS. Here, we provide a review of MRI and magnetic resonance spectroscopy (MRS studies that have been carried out in animal models of MS that focus on pathology. We compare the MRI phenotypes of animals and patients and provide advice on how best to use animal MR studies to increase our understanding of the linkages between MR and pathology in patients. This review describes how MRI studies of animal models have been, and will continue to be, used in the ongoing effort to understand MS.

  15. Bovine blood biomarkers as a way of processed animal proteins detection in feedingstuffs

    OpenAIRE

    Lecrenier, Marie-Caroline; Marbaix, Hélène; Veys, Pascal; Dieu, Marc; Raes, Martine; Berben, Gilbert; Saegerman, Claude; Baeten, Vincent

    2015-01-01

    The prohibition of using animal by-products in feedingstuffs depends on two factors: their nature defined by the tissue/cell type and the species of origin, and on their destination (pets, fur animals or other farmed animals). Proteomics is particularly well-suited to the purpose of PAPs detection as it is a tissue and species-specific method. The aim of this study was the identification and the selection of specific peptide biomarkers using tandem mass spectrometry for the detection of b...

  16. Veterinary information management system (VIMS) in the process of notification and management of animal diseases

    OpenAIRE

    Plavšić Budimir; Nedić D.; Mićović Z.; Tešić M.; Stanojević S.; Ašanin Ružica; Krnjaić D.; Tajdić Nada; Milanović S.

    2009-01-01

    A prerequisite to the development of an efficient animal health, food safety and traceability management system in the animal food production chain is the implementation of an integrated veterinary informational management system (VIMS) capable for the capture, storage, analysis and retrieval of data and providing the opportunity for the cumulative gathering of the knowledge and capability for its competent interpretation. Such a system will enable collecting appropriate data, including quali...

  17. Animal welfare evaluation at a slaughterhouse for heavy pigs intended for processing

    Directory of Open Access Journals (Sweden)

    Roberta Stocchi

    2014-03-01

    Full Text Available The Council Regulation (EC No. 1099/2009 requires slaughterhouse managers to implement specific standard operating procedures for all pre-slaughter stages considered at risk, aimed at achieving adequate levels of animal welfare. This survey was aimed at testing the applicability to an abattoir for heavy pigs of an assessment system of animal welfare through animal-based measures. In the monitoring of handling operations, the number of animals fallen/slipped and prodded, and that of vocalising pigs were recorded. In the monitoring of the immobilisation stage, carried out on the same pigs, vocalisations were recorded at the entrance to the box and falls/slips occurring inside it. Animal welfare assessment during the stunning-sticking-bleeding steps, was carried out by recording the head-only electrical stunning basic parameters set by legislation, vocalisations resulting from hot wanding, and clinical signs of consciousness, sensibility and certain death. Except for immobilisation, the percentage of occurrence of these events above acceptability limits was detected in all other preslaughter steps. The most critical stages were: handling in the unloading area and along the single-file chute, stunning and especially bleeding, where 84.13% of animals showed one or more signs of consciousness and/or sensibility recovery. Wrong placement of electrodes observed in 53.98% of the animals, insufficient voltage and low amperage may explain why a high percentage of pigs recovered consciousness and/or sensibility before death. Some simple restructuring of unloading area, slowdown of slaughter line speed, increase of personnel involved in pre-slaughter management and regular calibration of the electrical stunning device could be effectively corrective measures aimed at raising the animal welfare level at the slaughterhouse under study.

  18. Critical Analysis of Assessment Studies of the Animal Ethics Review Process

    OpenAIRE

    Orsolya Varga

    2013-01-01

    Simple Summary In many countries, the approval of animal research projects depends on the decisions of the ethics committees which review the projects. Since the efficiency of the protection of experimental animals greatly depends on the performance of the ethics committees, its regular assessment is crucial. This paper reviews the results of studies assessing the performance of the ethics committees, and emphasizes the importance of outcome assessment in the evaluation of the performance of ...

  19. Effect of low frequency magnetic field at reproductive system state and peroxidation processes in liver of male rates after low dose chronic irradiation

    International Nuclear Information System (INIS)

    Low frequency magnetic field (power 3.5 wt, tension 8v, amplitude 15 Tl, frequency of followed impulses 10 Hz, frequency of exposure 70-90 Hz) significantly modified the morphofunctional state of the reproductive system and peroxidation processes in liver of male rates. It concluded in a partial restoration of testicular weight, a recovery of the blood serum testosterone levels and of the molecular characteristics of the androgen receptor system in liver and testes, a normalization of peroxidation processes in liver and a stimulation of some biochemical and bioenergetic processes in testes (authors)

  20. Atypical centrioles during sexual reproduction

    OpenAIRE

    Avidor-Reiss, Tomer; Khire, Atul; Fishman, Emily L.; Jo, Kyoung H.

    2015-01-01

    Centrioles are conserved, self-replicating, microtubule-based, 9-fold symmetric subcellular organelles that are essential for proper cell division and function. Most cells have two centrioles and maintaining this number of centrioles is important for animal development and physiology. However, how animals gain their first two centrioles during reproduction is only partially understood. It is well established that in most animals, the centrioles are contributed to the zygote by the sperm. Howe...

  1. Algunos elementos para interpretar la presencia de los varones en los procesos de salud reproductiva Some elements for interpreting men's presence in reproductive health processes

    Directory of Open Access Journals (Sweden)

    Juan Guillermo Figueroa-Perea

    1998-01-01

    Full Text Available El objetivo del trabajo es identificar vertientes analíticas para ubicar a los varones en los procesos de salud reproductiva. Se propone cuestionar la interpretación que los identifica solamente como actores que pueden apoyar mejorías en la salud de las mujeres y de los hijos. Es reciente la inquietud por redimensionar su papel, como seres que se reproducen y enfrentan riesgos en su aparato, comportamiento y proceso reproductivos. Una posibilidad para explicitar la presencia de los varones en dichos procesos es identificar cuáles son sus ausencias y presencias que condicionan las consecuencias favorables o no para las mujeres y los hijos. Se trata de ver de qué manera dificultan o contribuyen a mejorar las condiciones de la morbimortalidad materna. Una segunda posibilidad es incursionar en el carácter relacional, social y potencialmente conflictivo de la reproducción "sexualizada". Implica replantear el análisis de la reproducción como un proceso relacional y no como eventos aislados de hombres y mujeres, al mismo tiempo que recuperar la especificidad de unos y de otras. Se utiliza la perspectiva de género con el fin de imaginar los procesos sin negar la dimensión del poder. Así, se replantean la sexualidad, la reproducción y la salud en términos de interacción, con el fin de construir referencias más claras respecto a la población masculina.This study aims to identify analytical approaches to situate men in processes pertaining to reproductive health. We challenge the position that identifies them only as actors that can support improvements in the health of women and children. More recently there has been a concern over reshaping their role, as individuals who both reproduce and face risks to their reproductive organs, behaviors, and processes. One possibility for explaining men's presence in such processes is to identify their absence or presence as conditioning the consequences for women and children. The issue is to

  2. Relationship of microbial processes to the fate and behavior of transuranic elements in soils, plants, and animals

    International Nuclear Information System (INIS)

    This review considers the influence of soil physicochemical and microbial processes on the long-term solubility, form, and bioavailability of plutonium and other transuranic elements important in the nuclear fuel cycle. Emphasis is placed on delineation of the relationships between soil chemical and microbial processes and the role of soil microorganisms in effecting solubilization, transformation and plant/animal uptake of elements considered largely insoluble in soils strictly on the basis of their inorganic chemical characteristics

  3. Test systems to identify reproductive toxicants.

    Science.gov (United States)

    Riecke, K; Stahlmann, R

    2000-09-01

    Experience with drugs and other xenobiotics indicates that both animal testing and epidemiological studies are necessary to provide adequate data for an estimation of risks that might be associated with exposure to a chemical substance. In this review, the pros and cons of test systems for reproductive toxicity are discussed. Usually, several studies are performed to cover the different phases of the reproductive cycle. In the preclinical development of drugs, the three so-called 'segment testing protocols' have been used for several decades now. More recently, new testing concepts have been accepted internationally which include more flexibility in implementation. Several examples of compounds with the potential for reproductive toxicity are presented in more detail in a discussion of some pitfalls of the tests for fertility (phthalates and fluoroquinolones), teratogenicity (acyclovir and protease inhibitors) and postnatal developmental toxicity (fluoroquinolones). In addition, important aspects of kinetics and metabolism as a prerequisite for a rational interpretation of results from toxicological studies are briefly discussed. In vitro assays are useful for supplementing the routinely used in vivo approaches or for studying an expected or defined effect, but they are not suitable for revealing an unknown effect of a chemical on the complex reproductive process. PMID:11021511

  4. Abnormal fear conditioning and amygdala processing in an animal model of autism

    DEFF Research Database (Denmark)

    Markram, Kamila; Rinaldi, Tania; La Mendola, Deborah;

    2008-01-01

    -treated animals displayed several symptoms common to autism, among them impaired social interactions and increased repetitive behaviors. Furthermore, VPA-treated rats were more anxious and exhibited abnormally high and longer lasting fear memories, which were overgeneralized and harder to extinguish. On the...... cellular level, the amygdala was hyperreactive to electrical stimulation and displayed boosted synaptic plasticity as well as a deficit in inhibition. We show for the first time enhanced, overgeneralized and resistant conditioned fear memories in an animal model of autism. Such hyperfear could be caused by...

  5. MultiTrust : Animating Multicriteria Decision-making Processes in the Organic Value Chain

    DEFF Research Database (Denmark)

    Kastberg, Peter

    2014-01-01

    the current media landscape. There is a tendency that they are predominantly used in one specific communicative constellation, i.e., when domain-specific knowledge is communicated from an expert or authority to a lay person. That, too, is the case when it comes to the animated film “MultiTrust” (to be found...

  6. Animal Behaviour Fieldwork: Introducing Psychology Students to the Process of Science

    Science.gov (United States)

    Dickins, Thomas E.; Donovan, Peter

    2012-01-01

    In this paper we discuss the development and running of a residential animal behaviour field trip. The trip has a number of elements that challenge and develop the students. First, this trip is open to students at levels two, three and M. This allows us to engineer a certain amount of peer assisted learning. Second, the students live together and…

  7. Controlling of crustacean zooplankton reproduction in biological activated carbon (BAC) filters by strengthen operation and management of conventional process

    Institute of Scientific and Technical Information of China (English)

    LIU Li-jun; ZHANG Jin-song; LI Xiao-wei; HE Jun-guo

    2010-01-01

    To counter the mass reproduction and penetration of crustacean zooplankton in Biological Activated Carbon (BAC) filters which may result in the presence of organisms in potable water and water pollution,this paper analyzed the factors affecting organisms' reproduction in BAC filters.A comparative study was performed on the density and composition of crustacean zooplankton of the concerned water treatment units of two advanced water plants (Plant A and B) which with the same raw water and the same treatment technique in southern China.The results obtained show that the crustaceans' density and composition was very different between the sand filtered water of Plant A and Plant B.which Harpacticoida bred sharply in the sediment tanks and penetrated sand filter into BAC falters was the primary reason of crustaceans reproduce in BAC filters of Plant A.For prevention of the organisms reproduction in BAC,some strengthen measures was taken including pre-chlorination,cleaning coagulation tanks and sediment tanks completely,increasing sludge disposal frequency to stop organisms enter BAC filters,and the finished water quality was improved and enhanced.

  8. Aging changes in the male reproductive system

    Science.gov (United States)

    Aging changes in the male reproductive system may include changes in testicular tissue, sperm production, and erectile ... during a process that some people call andropause. Aging changes in the male reproductive system occur primarily ...

  9. Improving animal productivity and reproductive efficiency: Development and testing medicated urea-molasses multi-nutrient blocks in rural farms of Bangladesh

    International Nuclear Information System (INIS)

    Urea-molasses multi-nutrient block (UMMB) is low-cost technology and has great potential to enhance the nutrition of ruminant livestock in Bangladesh and improve animal productivity. Where it is required, UMMB may also be formulated to include anthelmintic medication to control nematode parasites and further improve production. A series of studies was conducted to develop and extend these technologies to rural farmers of Bangladesh. By feeding UMMB to smallholder dairy cows in two areas it was found that live-weight (LW) and condition score tended to be improved and milk yield was increased by 32 - 33%. In a second experiment, growing calves belonging to rural farmers were given Albendazole (7.5 mg/kg), fresh pineapple leaf (1.6 g/kg LW) or fresh neem leaf (1 g/kg LW) in single as well as split doses. Faecal worm egg counts were reduced by all treatments but pineapple leaves showed higher efficacy (97%) than neem leaves (67%) and overall, divided doses had lower efficacy than the single dose. A third study was then conducted where UMMB, medicated UMMB (0.5 mg fenbendazole/kg block)) and unsupplemented controls were compared in lactating cows. Both treatments improved milk yield and live-weight gain (P <0.05). The medicated UMMB reduced faecal worm egg counts to zero while the UMMB without medication also yielded a 25% reduction. An on-station study was then conducted where pineapple leaf UMMB and neem leaf UMMB were compared to unmedicated UMMB. The blocks were prepared and fed in split doses over five days to lactating cows. Supplementation of UMMB with pineapple had significantly (P <0.01) higher efficacy in reducing faecal worm egg counts than UMMB with neem, which had a greater effect than unmedicated UMMB. Similar trends were also observed in improvements in milk yield, milk fat concentration and live-weight gain (P <0.05). The latter study was then repeated on rural farms where treatment efficacy and production responses were again clearly demonstrated for

  10. Estimating animal resource selection from telemetry data using point process models

    Science.gov (United States)

    Johnson, Devin S.; Hooten, Mevin B.; Kuhn, Carey E.

    2013-01-01

    Analyses of animal resource selection functions (RSF) using data collected from relocations of individuals via remote telemetry devices have become commonplace. Increasing technological advances, however, have produced statistical challenges in analysing such highly autocorrelated data. Weighted distribution methods have been proposed for analysing RSFs with telemetry data. However, they can be computationally challenging due to an intractable normalizing constant and cannot be aggregated (i.e. collapsed) over time to make space-only inference.

  11. Uncertainty in Population Estimates for Endangered Animals and Improving the Recovery Process

    OpenAIRE

    Rachlow, Janet L; Goble, Dale D.; Matthew Zak; J. Michael. Scott; Katie Hammond; Haines, Aaron M.

    2013-01-01

    Simple Summary The objective of our study was to evaluate the mention of uncertainty (i.e., variance) associated with population size estimates within U.S. recovery plans for endangered animals. To do this we reviewed all finalized recovery plans for listed terrestrial vertebrate species. We found that more recent recovery plans reported more estimates of population size and uncertainty. Also, bird and mammal recovery plans reported more estimates of population size and uncertainty. We recomm...

  12. Understanding disease processes in multiple sclerosis through magnetic resonance imaging studies in animal models

    OpenAIRE

    Nabeela Nathoo; V Wee Yong; Dunn, Jeff F.

    2014-01-01

    There are exciting new advances in multiple sclerosis (MS) resulting in a growing understanding of both the complexity of the disorder and the relative involvement of grey matter, white matter and inflammation. Increasing need for preclinical imaging is anticipated, as animal models provide insights into the pathophysiology of the disease. Magnetic resonance (MR) is the key imaging tool used to diagnose and to monitor disease progression in MS, and thus will be a cornerstone for future resear...

  13. Hedonic valuation of odor nuisance using field measurements, a case study of an animal waste processing facility in Flanders.

    OpenAIRE

    Eyckmans, Johan; De Jaeger, Simon; Rousseau, Sandra

    2011-01-01

    In this paper we estimate the external cost caused by odor from an animal waste processing facility in Flanders using new odor measures based on field measurements. We compare three different ways of incorporating odor nuisance indicators into the model: distance to the odor source, continuous odor measures, and a dummy variable approach comparable to the standard procedure in hedonic price analysis of noise pollution. We argue that the dummy variable approach is best suited to estimate the e...

  14. Experimental investigations on the effects of nuisances on reproduction processes in forest trees. 3. interim report. Experimentelle Untersuchungen ueber Immissionswirkungen auf Reproduktionsvorgaenge bei Waldbaeumen. 3. Zwischenbericht

    Energy Technology Data Exchange (ETDEWEB)

    Venne, H.; Scholz, F. (Bundesforschungsanstalt fuer Forst- und Holzwirtschaft, Grosshansdorf (Germany, F.R.). Inst. fuer Forstgenetik und Forstpflanzenzuechtung)

    1989-01-01

    The following parts of this project were to be looked into more closely: 1. Effects of gaseous pollutants on fecundation processes in vivo, seed formation and seed germination. 2. Differences between cross-breeds or genotypes in their sensitivity to air pollutants as to fertility and/or viability. During cross-breeding tests with two male and six female poplar clones, marked differences in the sensitivity to SO{sub 2} fumigation were noted in allthree partial tests: in the reproduction phase, the seedling stage, and in the group of one-year-old seedlings. (orig./MG).

  15. Reproductive epidemiology

    DEFF Research Database (Denmark)

    Olsen, Jørn; Nøhr, Ellen Aagaard

    2010-01-01

    Reproductive health covers a broad category of health and disease conditions, according to the Cairo Statement. This chapter focuses on subfecundity fertility, fetal death, malformations, pregnancy complications, sexual health, and diseases that may have their origin in fetal life, but which will...

  16. Male Reproductive System.

    Science.gov (United States)

    Turkington, B. A.

    This autoinstructional lesson deals with the study of the human body with emphasis on the life process of reproduction. It is a learning activity included in high school biology or health education classes. The behavioral objectives are listed and the equipment and materials needed to help the student gain these objectives are also included in the…

  17. Reproductive hacking. A male seminal protein acts through intact reproductive pathways in female Drosophila.

    Science.gov (United States)

    Rubinstein, C Dustin; Wolfner, Mariana F

    2014-01-01

    Seminal proteins are critical for reproductive success in all animals that have been studied. Although seminal proteins have been identified in many taxa, and female reproductive responses to receipt of these proteins have been documented in several, little is understood about the mechanisms by which seminal proteins affect female reproductive physiology. To explore this topic, we investigated how a Drosophila seminal protein, ovulin, increases ovulation rate in mated females. Ovulation is a relatively simple physiological process, with known female regulators: previous studies have shown that ovulation rate is promoted by the neuromodulator octopamine (OA) in D. melanogaster and other insects. We found that ovulin stimulates ovulation by increasing OA signaling in the female. This finding supports a model in which a male seminal protein acts through "hacking" a well-conserved, regulatory system females use to adjust reproductive output, rather than acting downstream of female mechanisms of control or in parallel pathways altogether. We also discuss similarities between 2 forms of intersexual control of behavior through chemical communication: seminal proteins and pheromones. PMID:25483253

  18. Abnormal fear conditioning and amygdala processing in an animal model of autism

    OpenAIRE

    Markram, Kamila; Rinaldi, Tania; La Mendola, Deborah; Sandi, Carmen; Markram, Henry

    2008-01-01

    A core feature of autism spectrum disorders is the impairment in social interactions. Among other brain regions, a deficit in amygdala processing has been suggested to underlie this impairment, but whether the amygdala is processing fear abnormally in autism, is yet not clear. We used the valproic acid (VPA) rat model of autism to (a) screen for autism-like symptoms in rats, (b) test for alterations in amygdala-dependent fear processing, and (c) evaluate neuronal reactivity and synaptic plast...

  19. Male Reproductive System

    Science.gov (United States)

    ... I Help a Friend Who Cuts? Male Reproductive System KidsHealth > For Teens > Male Reproductive System Print A ... reproductive systems. continue What Is the Male Reproductive System? Most species have two sexes: male and female. ...

  20. A quantitative real time polymerase chain reaction approach for estimating processed animal proteins in feed: preliminary data

    Directory of Open Access Journals (Sweden)

    Maria Cesarina Abete

    2013-04-01

    Full Text Available Lifting of the ban on the use of processed animal proteins (PAPs from non-ruminants in non-ruminant feed is in the wind, avoiding intraspecies recycling. Discrimination of species will be performed through polymerase chain reaction (PCR, which is at a moment a merely qualitative method. Nevertheless, quantification of PAPs in feed is needed. The aim of this study was to approach the quantitative determination of PAPs in feed through Real Time (RT-PCR technique; three different protocols picked up from the literature were tested. Three different kind of matrices were examined: pure animal meals (bovine, chicken and pork; one feed sample certified by the European reference laboratory on animal proteins (EURL AP in feed spiked with 0.1% bovine meal; and genomic DNAs from bovine, chicken and pork muscles. The limit of detection (LOD of the three protocols was set up. All the results obtained from the three protocols considered failed in the quantification process, most likely due to the uncertain copy numbers of the analytical targets chosen. This preliminary study will allow us to address further investigations, with the purpose of developing a RT-PCR quantitative method.

  1. An alternative for teaching and learning the simple diffusion process using Algodoo animations

    CERN Document Server

    da Silva, Samir L; da Silva, Rodrigo L; Viana, Emilson R; Leal, Fábio F

    2014-01-01

    In this work animations of the random walk movement using a freeware Algodoo were done in order to support teaching the concepts of Brownian Motion. The random walk movement were simulate considering elastic collision between the particles in suspension in a fluid, and the particles which constitute the fluid. The intensity of velocities where defined in an arbitrary range, and we have a random distribution of the velocity directions. Using two methods, the distribution histogram of displacements (DHD) and the mean-square-displacement ${\\langle{\\Delta r^{2}}\\rangle}$ (MSD), it was possible to measure the diffusion coefficient of the system, and determine the regions where the system presents ballistic regime or diffusive transport regime. The ballistic regime was observed graphically when the MSD has a parabolic dependence with time, which differing from the typical diffusive regime where MSD has a linear dependence. The didactical strategy for combining analytical approaches as graphic analysis, and animatio...

  2. Neuro-endocrine control of reproduction in hermaphroditic freshwater snails: mechanisms and evolution

    Directory of Open Access Journals (Sweden)

    Joris M Koene

    2010-10-01

    Full Text Available Invertebrates are used extensively as model species to investigate neuro-endocrine processes regulating behaviours, and many of these processes may be extrapolated to vertebrates. However, when it comes to reproductive processes, many of these model species differ notably in their mode of reproduction. A point in case are simultaneously hermaphroditic molluscs. In this review I aim to achieve two things. On the one hand, I provide a comprehensive overview of the neuro-endocrine control of male and female reproductive processes in freshwater snails. Even though the focus will necessarily be on Lymnaea stagnalis, since this is the best-studied species in this respect, extensions to other species are made wherever possible. On the other hand, I will place these findings in the actual context of the whole animal, after all these are simultaneous hermaphrodites. By considering the hermaphroditic situation, I uncover a numbers of possible links between the regulation of the two reproductive systems that are present within this animal, and suggest a few possible mechanisms via which this animal can effectively switch between the two sexual roles in the flexible way that it does. Evidently, this opens up a number of new research questions and areas that explicitly integrate knowledge about behavioural decisions (e.g., mating, insemination, egg laying and sexual selection processes (e.g., mate choice, sperm allocation with the actual underlying neuronal and endocrine mechanisms required for these processes to act and function effectively.

  3. 76 FR 43960 - NARA Records Reproduction Fees

    Science.gov (United States)

    2011-07-22

    ... RECORDS ADMINISTRATION 36 CFR Part 1258 RIN 3095-AB71 NARA Records Reproduction Fees AGENCY: National... its regulations to add the methodology for creating and changing records reproduction fees, to remove records reproduction fees found in its regulations, and to provide a notification process for the...

  4. Contextual processing deficits in PTSD: from animal models to fMRI studies

    OpenAIRE

    Israel Liberzon

    2012-01-01

    Background : Context processing imbues appropriate salience to the stimuli that is encountered. This ability enables us to hide from a predator in the wild, but to enjoy a visit to the zoo, although the lion may look the same in both contexts. Failures in contextual processing can lead to inappropriate fear responses rooted in failures to use safety cues, consider internal states, anticipate events, or appraise them properly. Posttraumatic stress disorder (PTSD) is associated with exaggerated...

  5. Exploring the Reproductive Decision-making Process of HIV-positive Women in County Victoria, Trinidad and Tobago

    Directory of Open Access Journals (Sweden)

    E Joseph

    2015-07-01

    Full Text Available Objective: The community-based Prevention of Mother to Child Transmission (PMTCT programme in Trinidad and Tobago offers care and support to HIV-positive (HIV+ pregnant women and their families for their lifetime. This study explored the factors influencing repeat childbearing by PMTCT enrolees. Method: In-depth qualitative interviews were conducted with purposively selected and consenting HIV+ women who enrolled in the PMTCT programme (n = 10 in County Victoria and four healthcare workers (HCWs. Transcribed interviews were analysed and coded using thematic content analysis. Results: Though women desired children and motherhood, some did not intend to conceive fearing HIV, age-related ill-health and vertical transmission. Others had not considered pregnancy and conceived through accident and partners’ disregard for the women’s HIV status, particularly if such partners were inebriated. Partners’ desire for children, especially in new relationships, led to planned pregnancies. Nine of the 10 HIV+ women did not seek family planning advice; the one that did was advised about partner infection but not risk reduction, vertical transmission or reinfection. Though HCWs supported HIV+ women’s reproductive rights, they agreed that HCWs stigmatized and discriminated against HIV+ mothers. Both parties saw the PMTCT programme as an effective programme in vastly reducing HIV transmission from mother to child. Conclusion: The PMTCT programme and family planning services should be integrated with tailored services toward HIV+ women and their partners to help them safely achieve their reproductive goals. Healthcare workers should be given training and skillsets to address stigma and discrimination against persons infected with HIV/AIDS within Trinidad and Tobago’s health workforce.

  6. Uncertainty in Population Estimates for Endangered Animals and Improving the Recovery Process

    Directory of Open Access Journals (Sweden)

    Janet L. Rachlow

    2013-08-01

    Full Text Available United States recovery plans contain biological information for a species listed under the Endangered Species Act and specify recovery criteria to provide basis for species recovery. The objective of our study was to evaluate whether recovery plans provide uncertainty (e.g., variance with estimates of population size. We reviewed all finalized recovery plans for listed terrestrial vertebrate species to record the following data: (1 if a current population size was given, (2 if a measure of uncertainty or variance was associated with current estimates of population size and (3 if population size was stipulated for recovery. We found that 59% of completed recovery plans specified a current population size, 14.5% specified a variance for the current population size estimate and 43% specified population size as a recovery criterion. More recent recovery plans reported more estimates of current population size, uncertainty and population size as a recovery criterion. Also, bird and mammal recovery plans reported more estimates of population size and uncertainty compared to reptiles and amphibians. We suggest the use of calculating minimum detectable differences to improve confidence when delisting endangered animals and we identified incentives for individuals to get involved in recovery planning to improve access to quantitative data.

  7. Animal Thermoregulation and the Operative Environmental (Equivalent) Temperature. Physical Processes in Terrestrial and Aquatic Ecosystems, Transport Process.

    Science.gov (United States)

    Stevenson, R. D.

    These materials were designed to be used by life science students for instruction in the application of physical theory to ecosystem operation. Most modules contain computer programs which are built around a particular application of a physical process. Thermoregulation is defined as the ability of an organism to modify its body temperature. This…

  8. Radiation processing technology for feed mixes and litter for laboratory animals

    International Nuclear Information System (INIS)

    The research was centred on feed mixes for laboratory rats and mice in conditions of germ-free and conventional breeding in isolators. Polyethylene was chosen as the most suitable packing material for radiation processing and subsequent storage. Pelleted diets and litter are packaged in three layers in 400x600 mm bags. 25 kGy for germ-free breeding and 50 kGy for gnotobiotic breeds of laboratory rats and mice were determined as being sufficient. The quality of processed diets and their effect on the weight and growth of rats is discussed. (Pu)

  9. Using Markov Decision Process to define an adaptive strategy to control the spread of an animal disease

    OpenAIRE

    Viet, Anne-France; Jeanpierre, Laurent; Bouzid, Maroua; Mouaddib, Abdel-Illah

    2012-01-01

    A strategy to control an animal disease within an area is often based on one or more actions systematically implemented. In this paper, we illustrate how to use a Markov Decision Process (MDP) to compute an adaptive strategy depending on the pathogen spread within a group of farmers with only one decisionmaker for the group. The objective at the group level is to decrease the cost of the disease and its control. Status for each farm is assumed to be exactly known each year by the decision-mak...

  10. Animating Critical Action Learning: Process-Based Leadership and Management Development

    Science.gov (United States)

    Trehan, Kiran; Pedler, Mike

    2009-01-01

    Increasing attention is focusing on the value of critical approaches to enhancing leadership and management development processes. This paper examines how a critical action learning perspectives can be harnessed to produce valuable learning and development through critically reflective practise. Critical action learning approaches not only explore…

  11. The role of social and ecological processes in structuring animal populations

    NARCIS (Netherlands)

    Farine, D.R.; Firth, J.A.; Aplin, L.M.; Crates, R.A.; Culina, Antica; Garroway, Colin J.; Hinde, C.A.

    2015-01-01

    Both social and ecological factors influence population process and structure, with resultant consequences for phenotypic selection on individuals. Understanding the scale and relative contribution of these two factors is thus a central aim in evolutionary ecology. In this study, we develop a fra

  12. The process of minimising medicine use through dialogue based animal health and welfare planning, Workshop report FIBL. In: CORE Organic project no. 1903 - ANIPLAN

    OpenAIRE

    Alfoeldi, Thomas; Gantner, Urs; Vaarst, Mette; Algers, Bo; Nicholas, Phillipa; Gratzer, Elisabeth; Henriksen, Britt I. F.; Mejdell, Cecilie; Hansen, Berit; Whay, Becky; Walkenhorst, Michael; Smolders, Gidi; Ivemeyer, Silvia; Hassing, M.; Roderick, Stephen

    2011-01-01

    The process of minimising medicine use through dialogue based animal health and welfare planning. Livestock are important in many organic farming systems, and it is an explicit goal to ensure high levels of animal health and welfare (AHW) through good management. In two previous EU network projects, NAHWOA & SAFO, it was concluded that this is not guaranteed merely by following organic standards. Both networks recommended implementation of individual animal health plans to stimulate organ...

  13. Petitioning process for irradiated foods and animal feeds in North America

    International Nuclear Information System (INIS)

    The lack of sufficient regulatory approvals continues to delay the commercial application of food irradiation in several countries. Often, the regulatory approval process itself appears too challenging and approvals are not even requested. The objective of this paper is to review petition requirements so that researchers and companies in other countries will be able to prepare petitions requesting approval for the import and sale of irradiated foods into North America. (author)

  14. Animated symbols

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2008-01-01

    This paper is based on data about animation film production by 18-year-old students in a Danish upper secondary school. The optic is the on-going potential for learning and development of reflection. The purpose is to clarify what might support young people's reflection on media. I propose...... an analytic working model called Animated Symbols concerning critical reflection in a dialogic learning process. The model shows dialogue as interactions that involve two types of transformation: inner ‘learning processes' and outer signs and symbols. The classroom-based research study is part of a Ph...

  15. Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α

    International Nuclear Information System (INIS)

    The foot-and-mouth disease virus leader proteinase (Lbpro) cleaves itself off the nascent viral polyprotein. NMR studies on the monomeric variant Lbpro L200F provide structural evidence for intramolecular self-processing. 15N-HSQC measurements of Lbpro L200F showed specifically shifted backbone signals in the active and substrate binding sites compared to the monomeric variant sLbpro, lacking six C-terminal residues. This indicates transient intramolecular interactions between the C-terminal extension (CTE) of one molecule and its own active site. Contrastingly, the porcine reproductive and respiratory syndrome virus (PRRSV) leader proteinase nsp1α, with a papain-like fold like Lbpro, stably binds its own CTE. Parts of the β-sheet domains but none of the α-helical domains of Lbpro and nsp1α superimpose; consequently, the α-helical domain of nsp1α is oriented differently relative to its β-sheet domain. This provides a large interaction surface for the CTE with the globular domain, stabilising the intramolecular complex. Consequently, self-processing inactivates nsp1α but not Lbpro. - Highlights: • We examine self-processing of the leader protease of foot-and-mouth disease virus. • NMR analysis strongly supports intramolecular self-processing. • Self-processing is a dynamic process with no stable complex. • Structural comparison with nsp1α of PRRSV which forms stable intramolecular complex. • Subdomain orientation explains differences in stability of intramolecular complexes

  16. ‘Expanding your mind’: the process of constructing gender-equitable masculinities in young Nicaraguan men participating in reproductive health or gender training programs

    Directory of Open Access Journals (Sweden)

    Virgilio Mariano Salazar Torres

    2012-08-01

    Full Text Available Background: Traditional forms of masculinity strongly influence men's and women's wellbeing. Objective: This study has two aims: (i to explore notions of various forms of masculinities in young Nicaraguan men participating in programs addressing sexual health, reproductive health, and/or gender equality and (ii to find out how these young men perceive their involvement in actions aimed at reducing violence against women (VAW. Design: A qualitative grounded theory study. Data were collected through six focus groups and two in-depth interviews with altogether 62 young men. Results: Our analysis showed that the informants experienced a process of change, labeled ‘Expanding your mind’, in which we identified four interrelated subcategories: The apprentice, The responsible/respectful man, The proactive peer educator, and ‘The feminist man’. The process showed how an increased awareness of gender inequities facilitated the emergence of values (respect and responsibility and behavior (thoughtful action that contributed to increase the informant's critical thinking and agency at individual, social, and political levels. The process was influenced by individual and external factors. Conclusions: Multiple progressive masculinities can emerge from programs challenging patriarchy in this Latin American setting. The masculinities identified in this study show a range of attitudes and behaviors; however, all lean toward more equitable gender relations. The results suggest that learning about sexual and reproductive health does not directly imply developing more gender-equitable attitudes and behaviors or a greater willingness to prevent VAW. It is paramount that interventions to challenge machismo in this setting continue and are expanded to reach more young men.

  17. NucleoCounter-An efficient technique for the determination of cell number and viability in animal cell culture processes.

    Science.gov (United States)

    Shah, Dimpalkumar; Naciri, Mariam; Clee, Paul; Al-Rubeai, Mohamed

    2006-05-01

    The NucleoCounter is a novel, portable cell counting device based on the principle of fluorescence microscopy. The present work establishes its use with animal cells and checks its reliability, consistency and accuracy in comparison with other cytometric techniques. The main advantages of this technique are its ability to handle a large number of samples with a high degree of precision and its simplicity and specificity in detecting viable cells quantitatively in a heterogeneous culture. The work addresses and overcomes the problems of subjectivity, and some of the inherent sampling errors associated with using the traditional haemocytometer and Trypan Blue exclusion method. NucleoCounter offers reduced intra- and inter-observer variation as well as consistency in repetitive analysis that establishes it as an efficient and highly potential device for at-line monitoring of animal cell processes. Furthermore, since the only manual steps required are sample aspiration and mixing with two reagents, it is feasible that the whole method could be automated and brought on-line for process monitoring and control. PMID:19002893

  18. [The effect of subchronic inhalations of nitric oxide on metabolic processes in blood of experimental animals].

    Science.gov (United States)

    Soloveva, A G; Peretyagin, S P

    2016-01-01

    Metabolic processes were investigated in plasma and erythrocytes of Wistar rats exposed to daily 10-min sessions of NO inhalation for 30 days. These included determination of glucose and lactate, catalase activity, and activities of aldehyde dehydrogenase (ALDH), lactate dehydrogenase (LDH), and catalase. NO inhalation in a concentration of 20 ppm, 50 ppm and 100 ppm caused an increase in glucose and lactate. Inhalation of 100 ppm NO also increased catalase activity. Inhalation of all NO concentrations resulted in a decrease of ALDH activity, while the decrease in LDH activity was observed at NO concentrations of 50-100 ppm. PMID:27143382

  19. Animating the biodynamics of soil thickness using process vector analysis: A dynamic denudation approach to soil formation

    Science.gov (United States)

    Johnson, D.L.; Domier, J.E.J.; Johnson, D.N.

    2005-01-01

    This paper expands the dynamic denudation framework of landscape evolution by providing new process insights and details on how soil and its signature morphological feature, the biomantle, form and function in the environment. We examine soils and their biomantles from disparate parts of the world, from the tropics through midlatitudes and hyperarid through perhumid, a range that exhibits varying environments for, and of, life. We then explicate the process pathways that cause soils to thicken and thin, and to even disappear, then reform. We do this by examining thickness relationships, where soil thickness stand biomantle thickness bt are functions of upbuilding u and deepening d minus removal r processes, hence st/bt=f(u+d-r). Upbuilding has two subsets, u1, which includes all exogenous (allochthonous-outside) mineral and/or organic inputs to the soil system, and u2, which includes all endogenous (autochthonous-in situ) processes and productions, including weathering. Exogenous u1 inputs include eolian and slopewash inputs (sedimentations) of mineral and organic materials, mass wasting accumulations and the like. Endogenous u2 processes and productions include the sum of in situ bioturbations, biosynthetic productions, organic accumulations, biovoid productions, weathering and volume increases caused by their sum. Endogenous upbuildings, which dominantly occur in the biomantle, are basically biodynamic bd processes and productions, hence u2=bd. Therefore, if exogenous upbuildings u1 are minimal or zero, then biomantle thickness bt is expressed by bt=f(u2-r) or bt=f(bd-r). Drawing on these relationships, we employ a graphic-conceptual device called process vector analysis in a digital animation (see supplementary materials or cf. https://netfiles.uiuc.edu/jdomier/www/temp/ biomantle.html) that illustrates the main pathways that form both Earth's soil and its unique epidermis, the biomantle. We then discuss the main elements of the animation using still frames that

  20. Phosphatidylserine translocation to the mitochondrion is an ATP-dependent process in permeabilized animal cells

    International Nuclear Information System (INIS)

    Chinese hamster ovary (CHO-K1) cells were pulse labeled with [3H]serine, and the synthesis of phosphatidyl[3H]ethanolamine from phosphatidyl[3H]serine during the subsequent chase was used as a measure of lipid translocation to the mitochondria. When the CHO-K1 cells were pulse labeled and subsequently permeabilized with 50 μg of saponin per ml, there was no significant turnover of nascent phosphatidyl[3H]serine to form phosphatidyl[3H]ethanolamine during an ensuring chase. Supplementation of the permeabilized cells with 2 mM ATP resulted in significant phosphatidyl[3H]ethanolamine synthesis (83% of that found in intact cells) from phosphatidyl[3H]serine during a subsequent 2-hr chase. Phosphatidyl[3H]ethanolamine synthesis essentially ceased after 2 hr in the permeabilized cells. The translocation-dependent synthesis of phosphatidyl[3H]ethanolamine was a saturable process with respect to ATP concentration in permeabilized cells. The conversion of phosphatidyl[3H]serine to phosphatidyl[3H]ethanolamine did not occur in saponin-treated cultures supplemented with 2 mM AMP, 2 mM 5'-adenylyl imidodiphosphate, or apyrase plus 2 mM ATP. ATP was the most effective nucleotide, but the addition of GTP, CTP, UTP, and ADP also supported the translocation-dependent synthesis of phosphatidyl[3H]ethanolamine albeit to a lesser extent. These data provide evidence that the interorganelle translocation of phosphatidylserine requires ATP and is largely independent of soluble cytosolic proteins

  1. Phosphatidylserine translocation to the mitochondrion is an ATP-dependent process in permeabilized animal cells

    Energy Technology Data Exchange (ETDEWEB)

    Voelker, D.R. (National Jewish Center for Immunology and Respiratory Medicine, Denver, CO (USA))

    1989-12-01

    Chinese hamster ovary (CHO-K1) cells were pulse labeled with ({sup 3}H)serine, and the synthesis of phosphatidyl({sup 3}H)ethanolamine from phosphatidyl({sup 3}H)serine during the subsequent chase was used as a measure of lipid translocation to the mitochondria. When the CHO-K1 cells were pulse labeled and subsequently permeabilized with 50 {mu}g of saponin per ml, there was no significant turnover of nascent phosphatidyl({sup 3}H)serine to form phosphatidyl({sup 3}H)ethanolamine during an ensuring chase. Supplementation of the permeabilized cells with 2 mM ATP resulted in significant phosphatidyl({sup 3}H)ethanolamine synthesis (83% of that found in intact cells) from phosphatidyl({sup 3}H)serine during a subsequent 2-hr chase. Phosphatidyl({sup 3}H)ethanolamine synthesis essentially ceased after 2 hr in the permeabilized cells. The translocation-dependent synthesis of phosphatidyl({sup 3}H)ethanolamine was a saturable process with respect to ATP concentration in permeabilized cells. The conversion of phosphatidyl({sup 3}H)serine to phosphatidyl({sup 3}H)ethanolamine did not occur in saponin-treated cultures supplemented with 2 mM AMP, 2 mM 5{prime}-adenylyl imidodiphosphate, or apyrase plus 2 mM ATP. ATP was the most effective nucleotide, but the addition of GTP, CTP, UTP, and ADP also supported the translocation-dependent synthesis of phosphatidyl({sup 3}H)ethanolamine albeit to a lesser extent. These data provide evidence that the interorganelle translocation of phosphatidylserine requires ATP and is largely independent of soluble cytosolic proteins.

  2. Animated Symbols

    DEFF Research Database (Denmark)

    Frolunde, Lisbeth

    ' processer af fem udvalgte elever er gennemgået i forhold til tre opdelinger: filmskabere, filmskabelse processen og film. Den teoretiske tilgang er pragmatisme, social semiotik og diskursanalyse. Modellen "Animating Symbols" er udviklet og diskuteret som forsøg på at forstå reflektion og design som en slags...

  3. Materials processing and in-vivo animal studies of nitrided hydroxyapatite bioceramics

    Science.gov (United States)

    Rashid, Nancy Elizabeth

    2000-10-01

    Calcium phosphate bioceramics are currently being used in medicine and dentistry, for reconstruction or repair of diseased or injured bone, but with limited success. Incorporating nitrogen into phosphate glasses has resulted in improved properties, and it is proposed that similar benefits may be gained from nitriding calcium phosphate bioceramics for bone implants as well. This work focuses on processing of hydroxyapatite and tricalcium phosphate bioceramics nitrided by using solid, liquid, gas and ion sources. These materials were characterized by chemical, structural, mechanical, and biological methods to determine both the material structure and their suitability as implant materials. Calcium nitride and NaPON glass were unsatisfactory sources of nitrogen for hydroxyapatite (HA) and/or tricalcium phosphate (TCP) ceramics. Calcium nitride, Ca3N2, is reacts with water vapor in the air, releasing ammonia, and leaving behind crystals of calcium oxide, CaO. The calcium oxide byproduct decreases the chemical stability of hydroxyapatite and HA/TCP composites in simulated body fluid. Sodium phosphorus oxynitride (NaPON) glass, in the form of a liquid sintering aid for HA, produces an inhomogeneous, composite as well. Hydroxyapatite heated at 800C in an ammonia atmosphere produces a homogeneous material with up to 2 wt% N. Infrared spectroscopy indicates cyanamide ions, CN22-, are formed by the incorporated nitrogen and impurity carbon. The use of 15N-doped ammonia results in an 15N NMR peak at 83.2 ppm, indicating P--N bonding. Raman spectroscopy may also indicate P--N bonding, but it is inconclusive. In a limited study, nitrogen may decrease the hardness and fracture toughness of the phosphate ceramic, hydroxyapatite, contrary to results expected for nitrogen in phosphate glasses. Nitrogen ions are incorporated in hydroxyapatite by ion implantation, with lower energies producing higher nitrogen contents. The highest concentration achieved was 3.55 wt% N, as determined

  4. Introduction: Imaging in reproduction.

    Science.gov (United States)

    Sella, Tamar; Laufer, Neri

    2016-06-01

    The authors of this Views and Reviews outline in detail the indispensable role of imaging tools-ultrasound, computed tomography, and magnetic resonance imaging-in the diagnosis and treatment of female and male factor infertility. Equipment producing diagnostic images, coupled with ever-increasing computing power, will pave the way for novel functional dynamic studies that will expand the understanding of reproductive processes and their management. PMID:27117374

  5. Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry.

    Science.gov (United States)

    Nácher-Mestre, Jaime; Ibáñez, María; Serrano, Roque; Boix, Clara; Bijlsma, Lubertus; Lunestad, Bjørn Tore; Hannisdal, Rita; Alm, Martin; Hernández, Félix; Berntssen, Marc H G

    2016-07-01

    There is an on-going trend for developing more sustainable salmon feed in which traditionally applied marine feed ingredients are replaced with alternatives. Processed animal products (PAPs) have been re-authorized as novel high quality protein ingredients in 2013. These PAPs may harbor undesirable substances such as pharmaceuticals and metabolites which are not previously associated with salmon farming, but might cause a potential risk for feed and food safety. To control these contaminants, an analytical strategy based on a generic extraction followed by ultra-high performance liquid chromatography coupled to high resolution mass spectrometry (UHPLC-HRMS) using quadrupole time-of-flight mass analyzer (QTOF MS) was applied for wide scope screening. Quality control samples, consisting of PAP commodities spiked at 0.02, 0.1 and 0.2 mg/kg with 150 analytes, were injected in every sample batch to verify the overall method performance. The methodology was applied to 19 commercially available PAP samples from six different types of matrices from the EU animal rendering industry. This strategy allows assessing possible emergent risk exposition of the salmon farming industry to 1005 undesirables, including pharmaceuticals, several dyes and relevant metabolites. PMID:27058915

  6. Sex-Specific Brain Deficits in Auditory Processing in an Animal Model of Cocaine-Related Schizophrenic Disorders

    Directory of Open Access Journals (Sweden)

    Patricia A. Broderick

    2013-04-01

    Full Text Available Cocaine is a psychostimulant in the pharmacological class of drugs called Local Anesthetics. Interestingly, cocaine is the only drug in this class that has a chemical formula comprised of a tropane ring and is, moreover, addictive. The correlation between tropane and addiction is well-studied. Another well-studied correlation is that between psychosis induced by cocaine and that psychosis endogenously present in the schizophrenic patient. Indeed, both of these psychoses exhibit much the same behavioral as well as neurochemical properties across species. Therefore, in order to study the link between schizophrenia and cocaine addiction, we used a behavioral paradigm called Acoustic Startle. We used this acoustic startle paradigm in female versus male Sprague-Dawley animals to discriminate possible sex differences in responses to startle. The startle method operates through auditory pathways in brain via a network of sensorimotor gating processes within auditory cortex, cochlear nuclei, inferior and superior colliculi, pontine reticular nuclei, in addition to mesocorticolimbic brain reward and nigrostriatal motor circuitries. This paper is the first to report sex differences to acoustic stimuli in Sprague-Dawley animals (Rattus norvegicus although such gender responses to acoustic startle have been reported in humans (Swerdlow et al. 1997 [1]. The startle method monitors pre-pulse inhibition (PPI as a measure of the loss of sensorimotor gating in the brain's neuronal auditory network; auditory deficiencies can lead to sensory overload and subsequently cognitive dysfunction. Cocaine addicts and schizophrenic patients as well as cocaine treated animals are reported to exhibit symptoms of defective PPI (Geyer et al., 2001 [2]. Key findings are: (a Cocaine significantly reduced PPI in both sexes. (b Females were significantly more sensitive than males; reduced PPI was greater in females than in males. (c Physiological saline had no effect on startle in

  7. What can other animals tell us about human social cognition? An evolutionary perspective on reflective and reflexive processing.

    Science.gov (United States)

    Hecht, E E; Patterson, R; Barbey, A K

    2012-01-01

    Human neuroscience has seen a recent boom in studies on reflective, controlled, explicit social cognitive functions like imitation, perspective-taking, and empathy. The relationship of these higher-level functions to lower-level, reflexive, automatic, implicit functions is an area of current research. As the field continues to address this relationship, we suggest that an evolutionary, comparative approach will be useful, even essential. There is a large body of research on reflexive, automatic, implicit processes in animals. A growing perspective sees social cognitive processes as phylogenically continuous, making findings in other species relevant for understanding our own. One of these phylogenically continuous processes appears to be self-other matching or simulation. Mice are more sensitive to pain after watching other mice experience pain; geese experience heart rate increases when seeing their mate in conflict; and infant macaques, chimpanzees, and humans automatically mimic adult facial expressions. In this article, we review findings in different species that illustrate how such reflexive processes are related to ("higher order") reflexive processes, such as cognitive empathy, theory of mind, and learning by imitation. We do so in the context of self-other matching in three different domains-in the motor domain (somatomotor movements), in the perceptual domain (eye movements and cognition about visual perception), and in the autonomic/emotional domain. We also review research on the developmental origin of these processes and their neural bases across species. We highlight gaps in existing knowledge and point out some questions for future research. We conclude that our understanding of the psychological and neural mechanisms of self-other mapping and other functions in our own species can be informed by considering the layered complexity these functions in other species. PMID:22866032

  8. Society of Reproductive Surgeons

    Science.gov (United States)

    The Society of Reproductive Surgeons Home About Us About SRS Mission Statement Officers The Role of Reproductive Surgeons For ... Fact Sheets and Booklets SRS is an affiliated society to the American Society for Reproductive Medicine . Below ...

  9. Normal Female Reproductive Anatomy

    Science.gov (United States)

    ... historical Searches are case-insensitive Reproductive System, Female, Anatomy Add to My Pictures View /Download : Small: 720x756 ... Large: 3000x3150 View Download Title: Reproductive System, Female, Anatomy Description: Anatomy of the female reproductive system; drawing ...

  10. Female reproductive disorders

    DEFF Research Database (Denmark)

    Crain, D Andrew; Janssen, Sarah J; Edwards, Thea M;

    2008-01-01

    To evaluate the possible role of endocrine-disrupting compounds (EDCs) on female reproductive disorders emphasizing developmental plasticity and the complexity of endocrine-dependent ontogeny of reproductive organs. Declining conception rates and the high incidence of female reproductive...

  11. Female Reproductive System

    Science.gov (United States)

    ... Things to Know About Zika & Pregnancy Female Reproductive System KidsHealth > For Parents > Female Reproductive System Print A ... or sperm. continue Components of the Female Reproductive System Unlike the male, the human female has a ...

  12. Reproduction, physiology and biochemistry

    Science.gov (United States)

    This chapter summarizes fundamental knowledge and recent discoveries about the reproduction, physiology and biochemistry of plant-parasitic nematodes. Various types of reproduction are reviewed, including sexual reproduction and mitotic and meiotic parthenogenesis. Although much is known about the p...

  13. Assisted Reproductive Technology (ART)

    Science.gov (United States)

    ... Information Clinical Trials Resources and Publications Assisted Reproductive Technology (ART) Skip sharing on social media links Share ... American Society for Reproductive Medicine. (2012). Assisted reproductive technologies: A guide for patients . Retrieved June 11, 2012, ...

  14. Male Reproductive System

    Science.gov (United States)

    ... Wrong With the Male Reproductive System en español Sistema reproductor masculino Reproduction All living things reproduce. Reproduction — ... cutting off its blood supply, is also a medical emergency that, thankfully, is not common. Surgery is ...

  15. The application of biotechnology in animal nutrition

    Directory of Open Access Journals (Sweden)

    Šefer Dragan

    2015-01-01

    Full Text Available Animal food has to incorporate multiple objectives, ie. it should provide good animal health, good production and reproductive performance, reduce pollution of the environment as well as have the impact on food of animal origin, by supplying it, in addition to basic nutrients, with certain useful substances that can act preventively on the occurrence of various diseases in humans in modern living conditions. This complex task implies the application of scientific knowledge concerning biotechnology in the field of animal feed production, and also includes the use of specific nutrients that are the result of the latest developments in specific disciplines such as molecular biology and genetic engineering. As a result of researches in these areas there were created some varieties of cereals and legumes with improved nutritional properties. On the other hand, obtaining a safe food of animal origin product imposes the use of substances of natural origin (such as probiotics, prebiotics, phytobiotics, enzymes, chelating forms .., which provide better digestibility and more complete utilization of certain nutrients from the feedstuff. In this way, the quantity of undigested substances are significantly reduced as well as soil and the atmosphere pollution. The use of specific additives in animal nutrition resulting from biotechnological research is most frequent when a problem concerning certain level of production or animal health has to be overcome. This implies a group of non-nutritional ingredients which are aimed to regulate the digestive tract microflora, pH, weight gain, as well as to modify metabolic processes etc.

  16. Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α

    Energy Technology Data Exchange (ETDEWEB)

    Steinberger, Jutta [Max F. Perutz Laboratories, Medical University of Vienna, Department of Medical Biochemistry, Dr. Bohr-Gasse 9/3, A-1030 Vienna (Austria); Kontaxis, Georg [Max F. Perutz Laboratories, University of Vienna, Department of Structural and Computational Biology, Campus Vienna Biocenter 5, A-1030 Vienna (Austria); Rancan, Chiara [Helmholtz Zentrum München, Department of Gene Vectors, Haematologikum, Marchioninistrasse 25, D-81377 Munich (Germany); Skern, Tim, E-mail: timothy.skern@meduniwien.ac.at [Max F. Perutz Laboratories, Medical University of Vienna, Department of Medical Biochemistry, Dr. Bohr-Gasse 9/3, A-1030 Vienna (Austria)

    2013-09-01

    The foot-and-mouth disease virus leader proteinase (Lb{sup pro}) cleaves itself off the nascent viral polyprotein. NMR studies on the monomeric variant Lb{sup pro} L200F provide structural evidence for intramolecular self-processing. {sup 15}N-HSQC measurements of Lb{sup pro} L200F showed specifically shifted backbone signals in the active and substrate binding sites compared to the monomeric variant sLb{sup pro}, lacking six C-terminal residues. This indicates transient intramolecular interactions between the C-terminal extension (CTE) of one molecule and its own active site. Contrastingly, the porcine reproductive and respiratory syndrome virus (PRRSV) leader proteinase nsp1α, with a papain-like fold like Lb{sup pro}, stably binds its own CTE. Parts of the β-sheet domains but none of the α-helical domains of Lb{sup pro} and nsp1α superimpose; consequently, the α-helical domain of nsp1α is oriented differently relative to its β-sheet domain. This provides a large interaction surface for the CTE with the globular domain, stabilising the intramolecular complex. Consequently, self-processing inactivates nsp1α but not Lb{sup pro}. - Highlights: • We examine self-processing of the leader protease of foot-and-mouth disease virus. • NMR analysis strongly supports intramolecular self-processing. • Self-processing is a dynamic process with no stable complex. • Structural comparison with nsp1α of PRRSV which forms stable intramolecular complex. • Subdomain orientation explains differences in stability of intramolecular complexes.

  17. The effects of oxidative stress on female reproduction: a review

    Directory of Open Access Journals (Sweden)

    Agarwal Ashok

    2012-06-01

    Full Text Available Abstract Oxidative stress (OS, a state characterized by an imbalance between pro-oxidant molecules including reactive oxygen and nitrogen species, and antioxidant defenses, has been identified to play a key role in the pathogenesis of subfertility in both males and females. The adverse effects of OS on sperm quality and functions have been well documented. In females, on the other hand, the impact of OS on oocytes and reproductive functions remains unclear. This imbalance between pro-oxidants and antioxidants can lead to a number of reproductive diseases such as endometriosis, polycystic ovary syndrome (PCOS, and unexplained infertility. Pregnancy complications such as spontaneous abortion, recurrent pregnancy loss, and preeclampsia, can also develop in response to OS. Studies have shown that extremes of body weight and lifestyle factors such as cigarette smoking, alcohol use, and recreational drug use can promote excess free radical production, which could affect fertility. Exposures to environmental pollutants are of increasing concern, as they too have been found to trigger oxidative states, possibly contributing to female infertility. This article will review the currently available literature on the roles of reactive species and OS in both normal and abnormal reproductive physiological processes. Antioxidant supplementation may be effective in controlling the production of ROS and continues to be explored as a potential strategy to overcome reproductive disorders associated with infertility. However, investigations conducted to date have been through animal or in vitro studies, which have produced largely conflicting results. The impact of OS on assisted reproductive techniques (ART will be addressed, in addition to the possible benefits of antioxidant supplementation of ART culture media to increase the likelihood for ART success. Future randomized controlled clinical trials on humans are necessary to elucidate the precise mechanisms

  18. EFFECTS OF PHYTOESTROGENS ON MAMMALIAN REPRODUCTIVE PHYSIOLOGY

    OpenAIRE

    Socorro Retana-Márquez; Horacio Hernández; José Alfredo Flores; Minerva Muñoz-Gutiérrez; Gerardo Duarte; Jesús Vielma; Gonzalo Fitz-Rodríguez; Ilda Graciela Fernández; Matthieu Keller; José Alberto Delgadillo

    2012-01-01

    Global consumption of phytoestrogens and their effects have increased both in animals and humans due to the augmented use of legumes in animal diets as well as the increase in vegetarian diets in some human populations. Phytoestrogens are found widely in a variety of plants and fodder, and can have adverse effects mainly on the reproductive tract in most animal species. Many phytoestrogens can act as estrogenic agonists or antagonists, and their effects can vary from an estrogenic over-respon...

  19. Chronic and reproduction studies in rats exposed to gasifier ash leachates.

    Science.gov (United States)

    Kostial, K; Rabar, I; Blanusa, M; Kello, D; Maljković, T; Landeka, M; Bunarević, A; Stara, J F

    1982-01-01

    Ash from the coal gasification process contains a broad spectrum of elements which through leaching (gasifier ash leachates) may enter into the environment. The health effect of such leachates i.e. complex mixtures of inorganic elements is insufficiently known. We investigated the effect of gasifier ash leachates in a chronic-(9-month) and in a three-generation reproduction study. The leachates were prepared weekly by water extraction of ash from a Lurgi coal gasification plant in Yugoslavia, and given to experimental animals instead of drinking water. In the chronic experiment exposed animals showed no changes in mortality rate, haematological findings, concentration of Fe, Zn, Mn in kidneys, liver, testicles and femur, as well as in femur composition and morphometry, gross pathology and organ histology. In the reproduction study the number of pregnancies, weight and number of newborns, and concentration of Fe, Zn, Mn in carcasses of sucklings were the same in control and experimental animals. PMID:7063833

  20. Molecular basis for regulating seasonal reproduction in vertebrates.

    Science.gov (United States)

    Nishiwaki-Ohkawa, Taeko; Yoshimura, Takashi

    2016-06-01

    Animals that inhabit mid- to high-latitude regions exhibit various adaptive behaviors, such as migration, reproduction, molting and hibernation in response to seasonal cues. These adaptive behaviors are tightly regulated by seasonal changes in photoperiod, the relative day length vs night length. Recently, the regulatory pathway of seasonal reproduction has been elucidated using quail. In birds, deep brain photoreceptors receive and transmit light information to the pars tuberalis in the pituitary gland, which induces the secretion of thyroid-stimulating hormone. Thyroid-stimulating hormone locally activates thyroid hormone via induction of type 2 deiodinase in the mediobasal hypothalamus. Thyroid hormone then induces morphological changes in the terminals of neurons that express gonadotropin-releasing hormone and facilitates gonadotropin secretion from the pituitary gland. In mammals, light information is received by photoreceptors in the retina and neurally transmitted to the pineal gland, where it inhibits the synthesis and secretion of melatonin, which is crucial for seasonal reproduction. Importantly, the signaling pathway downstream of light detection and signaling is fully conserved between mammals and birds. In fish, the regulatory components of seasonal reproduction are integrated, from light detection to neuroendocrine output, in a fish-specific organ called the saccus vasculosus. Various physiological processes in humans are also influenced by seasonal environmental changes. The findings discussed herein may provide clues to addressing human diseases, such as seasonal affective disorder. PMID:27068698

  1. Chromatin dynamics during plant sexual reproduction

    OpenAIRE

    She, Wenjing; Baroux, Célia

    2014-01-01

    Plants have the remarkable ability to establish new cell fates throughout their life cycle, in contrast to most animals that define all cell lineages during embryogenesis. This ability is exemplified during sexual reproduction in flowering plants where novel cell types are generated in floral tissues of the adult plant during sporogenesis, gametogenesis, and embryogenesis. While the molecular and genetic basis of cell specification during sexual reproduction is being studied for a long time, ...

  2. Neuroleptic Drugs Revert the Contextual Fear Conditioning Deficit Presented by Spontaneously Hypertensive Rats: A Potential Animal Model of Emotional Context Processing in Schizophrenia?

    OpenAIRE

    Calzavara, Mariana Bendlin; Medrano, Wladimir Agostini; Levin, Raquel; Kameda, Sonia Regina; Andersen, Monica Levy; Tufik, Sergio; Silva, Regina Helena; Frussa-Filho, Roberto; Abílio, Vanessa Costhek

    2008-01-01

    Schizophrenia, bipolar disorder, and attention deficit/hyperactivity disorder (ADHD) present abnormalities in emotion processing. A previous study showed that the spontaneously hypertensive rats (SHR), a putative animal model of ADHD, present reduced contextual fear conditioning (CFC). The aim of the present study was to characterize the deficit in CFC presented by SHR. Adult male normotensive Wistar rats and SHR were submitted to the CFC task. Sensitivity of the animals to the shock and the ...

  3. " Animal, trop animal "

    OpenAIRE

    Potestà, Andréa

    2010-01-01

    Dans la tradition philosophique, on trouve plusieurs définitions de l’homme. La célèbre définition aristotélicienne, zoon logon echon (animal doué du langage ou animal rationnel) fournit le paradigme ainsi que la méthode de toutes les définitions successives. Il s’agit d’ajouter au vivant, à l’animal, quelque chose d’autre, quelque chose de plus, qui permette de le caractériser et le fasse entendre comme différent des bêtes. Cette diversité peut être conçue différemment : en tant qu’élévation...

  4. Female reproductive disorders

    DEFF Research Database (Denmark)

    Crain, D Andrew; Janssen, Sarah J; Edwards, Thea M; Heindel, Jerrold; Ho, Shuk-mei; Hunt, Patricia; Iguchi, Taisen; Juul, Anders; McLachlan, John A; Schwartz, Jackie; Skakkebaek, Niels; Soto, Ana M; Swan, Shanna; Walker, Cheryl; Woodruff, Teresa K; Woodruff, Tracey J; Giudice, Linda C; Guillette, Louis J

    2008-01-01

    To evaluate the possible role of endocrine-disrupting compounds (EDCs) on female reproductive disorders emphasizing developmental plasticity and the complexity of endocrine-dependent ontogeny of reproductive organs. Declining conception rates and the high incidence of female reproductive...... disruptions warrant evaluation of the impact of EDCs on female reproductive health....

  5. Reproduction, symbiosis, and the eukaryotic cell.

    Science.gov (United States)

    Godfrey-Smith, Peter

    2015-08-18

    This paper develops a conceptual framework for addressing questions about reproduction, individuality, and the units of selection in symbiotic associations, with special attention to the origin of the eukaryotic cell. Three kinds of reproduction are distinguished, and a possible evolutionary sequence giving rise to a mitochondrion-containing eukaryotic cell from an endosymbiotic partnership is analyzed as a series of transitions between each of the three forms of reproduction. The sequence of changes seen in this "egalitarian" evolutionary transition is compared with those that apply in "fraternal" transitions, such as the evolution of multicellularity in animals. PMID:26286983

  6. Digital Realization of Traditional Animation Process---Taking Flash Paperless Animation System as an Example%传统动画制作工艺的数字化实现--以Flash无纸动画系统为例

    Institute of Scientific and Technical Information of China (English)

    王丛明

    2014-01-01

    本文首先总结了传统动画生产的工艺流程,然后按照流程顺序提出数字化的设想并论述了动画生产工艺流程数字化的优势,接着设计并论述了基于Flash技术进行传统动画生产工艺流程中各环节的实现。通过动画前期、中期、后期技术环节的解析与Flash技术的结合研究,设计了基于Flash动画技术的无纸动画制作系统的解决方案。%This paper first summarizes the process of traditional animation, and then proposes digital con-ceives according to the process and describes its advantage. The paper designs and discusses the realization of each link in the production of traditional animation based on Flash technology. Combining with the analysis on different steps of the animation technology and the Flash technology, we come to the Flash paperless animation system.

  7. Reproduction of Przewalski's Horse

    OpenAIRE

    Kovaříková, Lucie

    2012-01-01

    This work is about reproduction of Przewalski’s horses (Equus Przewalskii, Poliakov, 1881), which is similar to reproduction of domestic horses (Equus caballus, Linaeus, 1758). Przewalski’s horses are considered to only living ancestor of domestic horses, logically they have similar biology and reproduction. Despite different numbers of chromosome they could have fertile offspring. Reproductive differences are mainly in length of reproduction indicators. For example Przewalsky’s horses ar...

  8. The role of social and ecological processes in structuring animal populations: a case study from automated tracking of wild birds.

    Science.gov (United States)

    Farine, Damien R; Firth, Josh A; Aplin, Lucy M; Crates, Ross A; Culina, Antica; Garroway, Colin J; Hinde, Camilla A; Kidd, Lindall R; Milligan, Nicole D; Psorakis, Ioannis; Radersma, Reinder; Verhelst, Brecht; Voelkl, Bernhard; Sheldon, Ben C

    2015-04-01

    Both social and ecological factors influence population process and structure, with resultant consequences for phenotypic selection on individuals. Understanding the scale and relative contribution of these two factors is thus a central aim in evolutionary ecology. In this study, we develop a framework using null models to identify the social and spatial patterns that contribute to phenotypic structure in a wild population of songbirds. We used automated technologies to track 1053 individuals that formed 73 737 groups from which we inferred a social network. Our framework identified that both social and spatial drivers contributed to assortment in the network. In particular, groups had a more even sex ratio than expected and exhibited a consistent age structure that suggested local association preferences, such as preferential attachment or avoidance. By contrast, recent immigrants were spatially partitioned from locally born individuals, suggesting differential dispersal strategies by phenotype. Our results highlight how different scales of social decision-making, ranging from post-natal dispersal settlement to fission-fusion dynamics, can interact to drive phenotypic structure in animal populations. PMID:26064644

  9. Mechanisms linking energy balance and reproduction: impact of prenatal environment.

    Science.gov (United States)

    Rhinehart, Erin M

    2016-01-01

    The burgeoning field of metabolic reproduction regulation has been gaining momentum due to highly frequent discoveries of new neuroendocrine factors regulating both energy balance and reproduction. Universally throughout the animal kingdom, energy deficits inhibit the reproductive axis, which demonstrates that reproduction is acutely sensitive to fuel availability. Entrainment of reproductive efforts with energy availability is especially critical for females because they expend large amounts of energy on gestation and lactation. Research has identified an assortment of both central and peripheral factors involved in the metabolic regulation of reproduction. From an evolutionary perspective, these mechanisms likely evolved to optimize reproductive fitness in an environment with an unpredictable food supply and regular bouts of famine. To be effective, however, the mechanisms responsible for the metabolic regulation of reproduction must also retain developmental plasticity to allow organisms to adapt their reproductive strategies to their particular niche. In particular, the prenatal environment has emerged as a critical developmental window for programming the mechanisms responsible for the metabolic control of reproduction. This review will discuss the current knowledge about hormonal and molecular mechanisms that entrain reproduction with prevailing energy availability. In addition, it will provide an evolutionary, human life-history framework to assist in the interpretation of findings on gestational programming of the female reproductive function, with a focus on pubertal timing as an example. Future research should aim to shed light on mechanisms underlying the prenatal modulation of the adaptation to an environment with unstable resources in a way that optimizes reproductive fitness. PMID:26943613

  10. Establishing a process of irradiating small animal brain using a CyberKnife and a microCT scanner

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Haksoo; Welford, Scott [Department of Radiation Oncology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 (United States); Fabien, Jeffrey; Zheng, Yiran; Yuan, Jake; Brindle, James; Yao, Min; Lo, Simon; Wessels, Barry; Machtay, Mitchell; Sohn, Jason W., E-mail: jason.sohn@case.edu [Department of Radiation Oncology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 and University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, Ohio 44106 (United States); Sloan, Andrew [Department of Neurosurgery, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 (United States)

    2014-02-15

    Purpose: Establish and validate a process of accurately irradiating small animals using the CyberKnife G4 System (version 8.5) with treatment plans designed to irradiate a hemisphere of a mouse brain based on microCT scanner images. Methods: These experiments consisted of four parts: (1) building a mouse phantom for intensity modulated radiotherapy (IMRT) quality assurance (QA), (2) proving usability of a microCT for treatment planning, (3) fabricating a small animal positioning system for use with the CyberKnife's image guided radiotherapy (IGRT) system, and (4)in vivo verification of targeting accuracy. A set of solid water mouse phantoms was designed and fabricated, with radiochromic films (RCF) positioned in selected planes to measure delivered doses. After down-sampling for treatment planning compatibility, a CT image set of a phantom was imported into the CyberKnife treatment planning system—MultiPlan (ver. 3.5.2). A 0.5 cm diameter sphere was contoured within the phantom to represent a hemispherical section of a mouse brain. A nude mouse was scanned in an alpha cradle using a microCT scanner (cone-beam, 157 × 149 pixels slices, 0.2 mm longitudinal slice thickness). Based on the results of our positional accuracy study, a planning treatment volume (PTV) was created. A stereotactic body mold of the mouse was “printed” using a 3D printer laying UV curable acrylic plastic. Printer instructions were based on exported contours of the mouse's skin. Positional reproducibility in the mold was checked by measuring ten CT scans. To verify accurate dose delivery in vivo, six mice were irradiated in the mold with a 4 mm target contour and a 2 mm PTV margin to 3 Gy and sacrificed within 20 min to avoid DNA repair. The brain was sliced and stained for analysis. Results: For the IMRT QA using a set of phantoms, the planned dose (6 Gy to the calculation point) was compared to the delivered dose measured via film and analyzed using Gamma analysis (3% and 3 mm

  11. Establishing a process of irradiating small animal brain using a CyberKnife and a microCT scanner

    International Nuclear Information System (INIS)

    Purpose: Establish and validate a process of accurately irradiating small animals using the CyberKnife G4 System (version 8.5) with treatment plans designed to irradiate a hemisphere of a mouse brain based on microCT scanner images. Methods: These experiments consisted of four parts: (1) building a mouse phantom for intensity modulated radiotherapy (IMRT) quality assurance (QA), (2) proving usability of a microCT for treatment planning, (3) fabricating a small animal positioning system for use with the CyberKnife's image guided radiotherapy (IGRT) system, and (4)in vivo verification of targeting accuracy. A set of solid water mouse phantoms was designed and fabricated, with radiochromic films (RCF) positioned in selected planes to measure delivered doses. After down-sampling for treatment planning compatibility, a CT image set of a phantom was imported into the CyberKnife treatment planning system—MultiPlan (ver. 3.5.2). A 0.5 cm diameter sphere was contoured within the phantom to represent a hemispherical section of a mouse brain. A nude mouse was scanned in an alpha cradle using a microCT scanner (cone-beam, 157 × 149 pixels slices, 0.2 mm longitudinal slice thickness). Based on the results of our positional accuracy study, a planning treatment volume (PTV) was created. A stereotactic body mold of the mouse was “printed” using a 3D printer laying UV curable acrylic plastic. Printer instructions were based on exported contours of the mouse's skin. Positional reproducibility in the mold was checked by measuring ten CT scans. To verify accurate dose delivery in vivo, six mice were irradiated in the mold with a 4 mm target contour and a 2 mm PTV margin to 3 Gy and sacrificed within 20 min to avoid DNA repair. The brain was sliced and stained for analysis. Results: For the IMRT QA using a set of phantoms, the planned dose (6 Gy to the calculation point) was compared to the delivered dose measured via film and analyzed using Gamma analysis (3% and 3 mm). A

  12. Animal production and health newsletter. No. 26

    International Nuclear Information System (INIS)

    This issue of the newsletter highlights coordinated research programs in animal diseases including ELISA and RIA techniques in reproductive studies. Announcement of staff changes and forthcoming events are also covered

  13. Culturing Students' Practical Innovation Ability by Constructing the Opening Experiment Teaching Platform of Animal Reproduction%构建《动物繁殖学》开放式实验教学平台培养学生实践创新能力

    Institute of Scientific and Technical Information of China (English)

    李晓霞

    2012-01-01

    The research aimed to further improve the experimental teaching quality of Animal Reproduction,mobilize the initiative and creativity of students,enhance the experimental operation skills of students and cultivate high-quality innovative talent.Based on experimental teaching practice and available experimental teaching resources,the necessity,existing problems and suggestions of constructing the opening experimental teaching platform of Animal Reproduction were discussed.%为进一步提高《动物繁殖学》实验教学质量,充分调动学生的主动性和创新性,提高学生的实验操作技能,培养应用型高素质创新人才,结合多年的实验教学经验和现有实验教学资源,阐述了构建《动物繁殖学》开放式实验教学平台的必要性、存在的问题及建议。

  14. 我国五十年来海洋动物发育与 繁殖生物学的研究进展%Advanced in the Developmental and Reproductive Biology of Marine Animal during the Past 50 Years in China

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This paper reviews the achievements in developmental and reproductive biology of marine economic animals since the establishment of the People's Republic of China. The first achievements are the studies of embryo nic development of amphioxus by professor Tong Dizhou (the famous experimental e mbryologist in China) and his collaborat ors in the 1950's to 1990's. The second ones are the studies on the development, habits and characteristics of shipworm s, as well as reproduction in advance and raising seedlings indoor by professor Wu Shangqin (the famous embryologist of marine animal in China) and her collabor ators at the end of 1950's to the beginning of the 1960's. In the 1960's, Zhao F azhen (academician of Academy of Sciences in China) and his collaborators resear ched larval development and artificial seedling of Penaeus chinensis. In fis h, the main studies were focused on embryonic development, ultrastructure of spe rm in a variety of fish. In crustacea, the main researches were centralized in l ife history, reproductive habits and characteristics, genesis of germ cells and impregnation biology in economic prawn, crab and atemia. The life history, devel opmentl of gonad, genesis and ultrastructure of germ cells were studied of some economic seashells.%我国在海洋动物发育与繁殖生 物学方面的研究是随着国民经济的迅速发展而起步的,并且在某些方面已取得了举世瞩目的 成就。作者着重对我国近50年来,海洋经济动物的发育和繁殖生物学研究作一综述。

  15. Amazing Animals

    Science.gov (United States)

    Al-Kuwari, Najat Saad

    2007-01-01

    "Animals" is a three-part lesson plan for young learners with a zoo animal theme. The first lesson is full of activities to describe animals, with Simon Says, guessing games, and learning stations. The second lesson is about desert animals, but other types of animals could be chosen depending on student interest. This lesson teaches…

  16. Ambystoma maculatum (spotted salamander). Reproduction

    Science.gov (United States)

    Glorioso, Brad M.; Waddle, Hardin; Hefner, Jeromi

    2012-01-01

    The Spotted Salamander is a wide-ranging salamander of the eastern United States that typically breeds in winter or early spring in ephemeral pools in lowland forests. Ambystoma maculatum is known to deposit 2-4 egg masses per year, each containing 1-250 eggs. As part of ongoing research into the ecology and reproductive biology of Spotted Salamanders in the Kisatchie District of Kisatchie National Forest in Natchitoches Parish, Louisiana, USA, we have been counting the number of embryos per egg mass. We captured seven female A. maculatum in a small pool, six of which were still gravid. We took standard measurements, including SVL, and then implanted a Passive Integrated Transponder (PIT tag) into each adult female as was the protocol. About an hour after processing these animals we marked new A. maculatum egg masses found in the same small pool using PVC pin flags pushed carefully through the outer jelly. We did not have enough time to process them that evening, and it was not until a few days later that we photographed those masses. We discovered that one of the masses contained a PIT tag in the outer jelly that corresponded to one of the six gravid females that were marked that same evening. To our knowledge, this is the first report of PIT tags being the means, albeit coincidentally, by which a particular egg mass of Ambystoma maculatum has been assigned to a particular female. For our purposes, losing the PIT tag from the adult female is counter to the goals of our study of this population, and we will no longer be implanting PIT tags into gravid females.

  17. Improving artificial breeding of cattle and buffalo in Asia. Guidelines and recommendations. A manual prepared under the framework of an IAEA Technical Cooperation Regional RCA Project on 'Improving Animal Productivity and Reproductive Efficiency', with technical support of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture

    International Nuclear Information System (INIS)

    The International Atomic Energy Agency (IAEA) and the Regional Cooperative Agreement for Asia and the Pacific Region (RCA), with technical support of the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, implemented a Technical Cooperation (TC) project entitled Improving Animal Productivity and Reproductive Efficiency. The dual objectives of this project are (a) strengthening and extending the field applications of Urea Molasses Multinutrient Blocks (UMMB) and other feed supplementation strategies, and (b) monitoring and improving the reproductive management and fertility of smallholder dairy cattle subjected to Artificial Insemination (AI). The radioimmunoassay (RIA) for measurement of progesterone in milk and use of the computer database AIDA (Artificial Insemination Database Application) play important roles in the success of the latter objective. The first meeting to plan project activities was held in January 1999 in Yangon, Myanmar and the second meeting to review progress and develop further work plans was held in February 2000 in Kuala Lumpur, Malaysia. The latter meeting concluded that the procedures currently used by different Asian countries for evaluation of breeding bulls should be standardized and unified protocols developed for ensuring quality control of semen during processing, storage and field use. It was recommended that this should be accomplished through a regional workshop of national consultants. A workshop of national consultants from 10 RCA Member States was therefore held in April 2002 in Faisalabad, Pakistan, to consider and discuss the following aspects and arrive at a consensus on the best procedures and practices to be adopted to suit conditions and needs in developing countries of Asia: - Selection, management and health control of AI bulls; - Semen technologies from collection through processing to storage; - Delivery and follow-up of field AI services to farmers The IAEA has also supported a similar project in

  18. Reproductive Technology in the Context of Reproductive Teleology

    Science.gov (United States)

    Cooper, Neil J.; Hampton, Simon Jonathan

    2007-01-01

    This article argues that in the ordinary course of events, most parents routinely practice "reproductive teleology" in that they attempt to manipulate the physical and psychological characteristics of children, and they do so as part of the process of good parenting. Furthermore, such attempts are socially approved of and encouraged. With these…

  19. Reproductive Disorders in Cattle due to Nutritional Status

    OpenAIRE

    Pradhan, Rajani; Nakagoshi, Nobukazu

    2008-01-01

    This review presents a brief overview on nutrition and incidences of reproductive problems in cattle. Overfeeding and underfeeding are equally detrimental to normal reproductive function. The exact mechanism of nutrition on reproduction is still not clear, but it is clear that the primary target area for sensing and reacting to nutritional status is the hypothalamus. Nutrition or perhaps more specifically certain food nutrients can influence the hormonal status of animals at several levels. G...

  20. Animal models of cerebral ischemia

    Science.gov (United States)

    Khodanovich, M. Yu.; Kisel, A. A.

    2015-11-01

    Cerebral ischemia remains one of the most frequent causes of death and disability worldwide. Animal models are necessary to understand complex molecular mechanisms of brain damage as well as for the development of new therapies for stroke. This review considers a certain range of animal models of cerebral ischemia, including several types of focal and global ischemia. Since animal models vary in specificity for the human disease which they reproduce, the complexity of surgery, infarct size, reliability of reproduction for statistical analysis, and adequate models need to be chosen according to the aim of a study. The reproduction of a particular animal model needs to be evaluated using appropriate tools, including the behavioral assessment of injury and non-invasive and post-mortem control of brain damage. These problems also have been summarized in the review.

  1. Animal Models for imaging

    OpenAIRE

    Croft, Barbara Y.

    2002-01-01

    Animal models can be used in the study of disease. This chapter discusses imaging animal models to elucidate the process of human disease. The mouse is used as the primary model. Though this choice simplifies many research choices, it necessitates compromises for in vivo imaging. In the future, we can expect improvements in both animal models and imaging techniques.

  2. Animal Testing

    Science.gov (United States)

    Moretto, Johnny; Chauffert, Bruno; Bouyer, Florence

    The development of a new anticancer drug is a long, complex and multistep process which is supervised by regulatory authorities from the different countries all around the world [1]. Application of a new drug for admission to the market is supported by preclinical and clinical data, both including the determination of pharmacodynamics, toxicity, antitumour activity, therapeutic index, etc. As preclinical studies are associated with high cost, optimization of animal experiments is crucial for the overall development of a new anticancer agent. Moreover, in vivo efficacy studies remain a determinant panel for advancement of agents to human trials and thus, require cautious design and interpretation from experimental and ethical point of views.

  3. Squalus cubensis Reproduction Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Reproductive data from Squalus cubensis (Cuban dogfish) were opportunistically collected from 2005-2012. Data include those necessary to examine reproductive cycle,...

  4. [Reproductive toxicity of lindane].

    Science.gov (United States)

    Pagès, Nicole; Sauviat, Martin-Pierre; Bouvet, Suzanne; Goudey-Perrière, Françoise

    2002-01-01

    The present paper bears on the main effects of lindane (gamma isomer of hexachlorocyclohexane) on endocrine and reproductive functions in mammals. This pesticide, once widely used to kill lice and a variety of pests that attack agricultural products, livestock and trees, has been progressively eliminated from many applications since the mid-1970s in Europe or USA, but is still used in the rest of the world. Lindane is absorbed through respiratory, digestive or cutaneous routes and accumulates in fat tissues. It damages human liver, kidney, neural and immune systems and induces birth defects, cancer and death. Chronic administration results in endocrine disruption in birds as well as in mammals. Treatment with 1-40 mg of lindane/kg b.w. disrupts testicular morphology, decreases spermatogenesis, inhibits testicular steroidogenesis, reduces plasma androgen concentrations and may adversely affect reproductive performances in males. In females, lindane disrupts the estrous cycle, reduces serum estrogen and progesterone levels, decreases sexual receptivity whereas in pregnant dams it decreases whelping rate and litter size. These effects were also observed in some rats exposed to residual environmental doses. In addition, there is concern that irreversible effects may be induced when animals are exposed to endocrine disrupting chemicals during critically susceptible phases of sexual differentiation or development. These effects would results from (i) alterations of gonade or gamete cell membranes (ii) cell metabolism changes including alterations of ionic exchanges (mainly calcium or potassium), direct or free radical-mediated inhibition of steroidogenesis (iii) or neuroendocrine changes leading to a decrease in sexual performance of either parents or their offsprings exposed in utero or through lactation. PMID:12645304

  5. Reproductive tract microbiome in assisted reproductive technologies.

    Science.gov (United States)

    Franasiak, Jason M; Scott, Richard T

    2015-12-01

    The human microbiome has gained much attention recently for its role in health and disease. This interest has come as we have begun to scratch the surface of the complexity of what has been deemed to be our "second genome" through initiatives such as the Human Microbiome Project. Microbes have been hypothesized to be involved in the physiology and pathophysiology of assisted reproduction since before the first success in IVF. Although the data supporting or refuting this hypothesis remain somewhat sparse, thanks to sequencing data from the 16S rRNA subunit, we have begun to characterize the microbiome in the male and female reproductive tracts and understand how this may play a role in reproductive competence. In this review, we discuss what is known about the microbiome of the reproductive tract as it pertains to assisted reproductive technologies. PMID:26597628

  6. Reproduction and genetic diversity of the swamp buffalo

    NARCIS (Netherlands)

    Yindee, M.

    2010-01-01

    The water buffalo is one of the most important domestic animals in Southeast Asia including Thailand. As the Thai swamp buffalo population declined during the last two decades, the swamp buffalo reproductive performance needs to be improved. Lack of knowledge on swamp buffalo reproduction, improper

  7. Nuclear techniques in animal production and health and food irradiation

    International Nuclear Information System (INIS)

    Nuclear techniques applied to animal production and health are concentrated in three main fields: Animal nutrition, reproduction and animal health. Isotopic markers, both radioactive (''1''4C, ''51Cr, 32P and 35S) and stable (15N), have been used in the development of feeding strategies by understanding the rumen fermentation process, and how protein and other nutrients are utilized to determine a balanced diet for meeting animal requirements for growth, pregnancy and lactation. The simple and easily applicable technology was developed for the preparation of a urea mineral multi nutrient block as a supplement and animal cake for the replacement of concentrate feed used by dairy cattle holders. The model was developed in Yerli Kara Cattle and its cross-breeds to estimate protein requirements of animals. Progesterone immunoassays (RIA/EIA) make it possible to control the reproductive performance of cattle, sheep and goats. A milk progesterone enzyme immunoassay kit known as Reprokon was developed at our Center. The kit has licensed by the Ministry of Agriculture and Rural Affairs. As for animal diseases, especially parasitic infections, nuclear techniques have proved to be of great value, namely in the production of irradiated vaccines against helminitic diseases. The Enzyme Linked Immunosorbent assay (ELISA) diagnostic techniques were used on the diagnosis of babesiosis, a disease which cause great economic loss in livestock in Turkey. Food irradiation is the treatment of raw, semi-processed or processed food or food ingredients with ionizing radiation to achieve a reduction of losses due to insect infestation, germination of root crops, spoilage and deterioration of perishable produce, and/or the control of microorganisms and other organisms that cause food borne diseases

  8. Nuclear techniques in animal agriculture

    International Nuclear Information System (INIS)

    Nuclear technology plays an integral part in research to improve the health and productivity of animals. The use of radioisotopes and ionizing radiations in animal agriculture is briefly reviewed. The radioimmunoassay techniques give the opportunity of measuring and following precisely hormonal patterns in animals over the reproductive cycle. Simply by analysing a sample of blood, milk, or other body fluid, minute hormone concentrations can be assayed and the reproductive status of the animal assessed. The radioimmunoassay procedure uses antigens which are isotopically labelled, usually with 125I, and antibodies specifically developed for each hormone. The onset of sexual maturity, of oestrus, or the influence of environmental, nutritional or other factors on the reproductive state of an animal can be studied. An example of the use of the radioimmunoassay technique is illustrated in the coordinated research program of the IAEA which focuses on improving domestic buffalo production. Nuclear techniques, particularly the use of stable and radioactive tracers are providing important insights into the functioning of the digestive system of ruminants, its qualitative dynamics and metabolism. For assessing the products of the rumen, particularly volatile fatty acids which become an energy source, and microbial proteins which become a protein source for the animal, materials labelled with 14C, 3H, 35S, 15N and 32P are used. As an illustrative example, the results of one study of nitrogen metabolism, microbial protein and rumen bypass protein synthesis in cattle are shown

  9. Laboratory Animal Management: Wild Birds.

    Science.gov (United States)

    National Academy of Sciences - National Research Council, Washington, DC. Inst. of Lab. Animal Resources.

    This is a report on the care and use of wild birds in captivity as research animals. Chapters are presented on procurement and identification, housing, nutrition, health of birds and personnel, reproduction in confinement, and surgical procedures. Also included are addresses of federal, state, and provencial regulatory agencies concerned with wild…

  10. Gender and social reproduction: historical perspectives.

    Science.gov (United States)

    Laslett, B; Brenner, J

    1989-01-01

    It is argued that gender relations and social reproduction were both shaped by macrohistorical processes and shaped the processes. Social reproduction is defined within feminist theory as more than production in the Marxist sense. Societal reproduction is a combination of the organization of production, the organization of social reproduction, the perpetuation of gender, and the continuation of class relations. Social reproduction includes the care and socialization of children and care of the elderly or infirm. Social reproduction includes the organization of sexuality, biological reproduction, and how food, clothing, and shelter are made available. Most social reproduction occurs within the family unit. It is pointed out that variations in the distribution of the work of social reproduction are affected by the family, market, community, and state. The ways in which women construct their own worlds of activity is a central concern. The feminist concept of social reproduction differs from modernization theory, which is concerned with the institutional location of the tasks of social reproduction and the structural effects on the family and gender relations. This literature review focuses only on the history of family strategies and separate gender-related activities. The authors describe the changes in family organization that define men as income producers and women as caretakers, who base child rearing on love and feminine virtue rather than patriarchal authority and religious doctrine. The discussion focuses on the differences in marital relationships, motherhood, and sexuality between upper and middle class and working class women in the 19th century. Among working class women, a good wife was an efficient manager, a skilled domestic worker, and an income earner. The turn of the century was a period of social change marked by smaller average family size, the decline of household production, the rise in real wages, and increased consumption. It is argued that

  11. Geography and Dynamics of the Industries Processing Raw Materials of Animal Origin in the Villages of Kharkiv Region during the NEP

    Directory of Open Access Journals (Sweden)

    A. Lapchenko

    2016-02-01

    Full Text Available Background research related to the lack of researches in the given topic historiography. Territorial boundaries cover a large region — Kharkiv region, which until 1925 largely coincide with the boundaries of Kharkov province. And in 1925, it was divided into several provinces — Kharkov, Sumy, Kupiansk, Izyumskogo, Romney. The chronological boundaries article dated from 1921–1929’s, during which was implemented new economic polityka.Osnovnu attention paid to the article features geographically-sectoral design small-scale production of animal products in the region in 20 years of the twentieth century. On the basis of the detected and studied complex of sources the author analyzes the source base peasant industries in Kharkiv in this period. Found total number of farmers who were engaged in crafts processing animal products. Also revealed the specific industry Kharkov peasantry during nepu. Isnuvav number of factors that pushed the peasant engage in crafts: surplus agricultural products and raw materials; meet a wide range of numerous industrial, domestic and cultural needs; urgent need to replenish the family budget; surplus labor; free time from agricultural work (especially in winter and others. The development of rural industries processing animal products in the years 1921–1929 in the Kharkiv region characterized by strength and diversity. Village artisans representing an original way of small private commodity production. Basically crafts processing animal products involved in two socio-professional groups: lone artisan and peasant host of crafts. The social basis of industrial employment accounted malozemelni without sowing without Traction economy, which crafts were an important source of household income. The attention is focused on characteristic features of the state policy on «small business » peasants. Attention is paid to co-operation and effects of these industries on the further development rozvytok. Kooperatyvna form

  12. 78 FR 34565 - Irradiation in the Production, Processing, and Handling of Animal Feed and Pet Food; Electron...

    Science.gov (United States)

    2013-06-10

    ... (78 FR 27303). That document used incorrect style for the strength units describing radiation sources... Register of May 10, 2013 (78 FR 27303). That document used incorrect style for the strength units..., and Handling of Animal Feed and Pet Food; Electron Beam and X-Ray Sources for Irradiation of...

  13. Neuropeptidomics applied to studies of mammalian reproduction

    Directory of Open Access Journals (Sweden)

    Le Thao T.

    2014-01-01

    Full Text Available Neuropeptidomics, a mass spectrometry-based technique which aims to uncover the complete suite of neuropeptides present in a tissue, organ or cell from the brain or nervous system, has found application in studies examining physiological responses (e.g. food intake, appetite and reproduction. Neuropeptides (and peptide hormones have long been known as regulators of mammalian physiological processes, particularly reproduction. These peptides are derived from precursor proteins and become active via proteolytic processes and post-translational modifications. A relatively large number of neuropeptides, mainly formed in the hypothalamus or the anterior pituitary of mammals, have been specifically associated with reproduction, including GnRH, NPY, PYY and kisspeptin. Here, we will present an overview of neuropeptides, their roles in reproduction and the application of neuropeptidomics in this field. We address the advantages of neuropeptidomics in reproductive studies including the high throughput identification, profiling and quantification of neuropeptides present in reproductive tissues and also discuss some of the challenges. The application of neuropeptidomics to the field of reproduction will provide the foundation for a greater understanding of how neuropeptides act to regulate reproductive function.

  14. Neuroleptic drugs revert the contextual fear conditioning deficit presented by spontaneously hypertensive rats: a potential animal model of emotional context processing in schizophrenia?

    Science.gov (United States)

    Calzavara, Mariana Bendlin; Medrano, Wladimir Agostini; Levin, Raquel; Kameda, Sonia Regina; Andersen, Monica Levy; Tufik, Sergio; Silva, Regina Helena; Frussa-Filho, Roberto; Abílio, Vanessa Costhek

    2009-07-01

    Schizophrenia, bipolar disorder, and attention deficit/hyperactivity disorder (ADHD) present abnormalities in emotion processing. A previous study showed that the spontaneously hypertensive rats (SHR), a putative animal model of ADHD, present reduced contextual fear conditioning (CFC). The aim of the present study was to characterize the deficit in CFC presented by SHR. Adult male normotensive Wistar rats and SHR were submitted to the CFC task. Sensitivity of the animals to the shock and the CFC performance after repeated exposure to the task were investigated. Pharmacological characterization consisted in the evaluation of the effects of the following drugs administered previously to the acquisition of the CFC: pentylenetetrazole (anxiogenic) and chlordiazepoxide (anxiolytic); methylphenidate and amphetamine (used for ADHD); lamotrigine, carbamazepine, and valproic acid (mood stabilizers); haloperidol, ziprasidone, risperidone, amisulpride, and clozapine (neuroleptic drugs); metoclopramide and SCH 23390 (dopamine antagonists without antipsychotic properties); and ketamine (a psychotomimmetic). The effects of paradoxical sleep deprivation (that worsens psychotic symptoms) and the performance in a latent inhibition protocol (an animal model of schizophrenia) were also verified. No differences in the sensitivity to the shock were observed. The repeated exposure to the CFC task did not modify the deficit in CFC presented by SHR. Considering pharmacological treatments, only the neuroleptic drugs reversed this deficit. This deficit was potentiated by proschizophrenia manipulations. Finally, a deficit in latent inhibition was also presented by SHR. These findings suggest that the deficit in CFC presented by SHR could be a useful animal model to study abnormalities in emotional context processing related to schizophrenia. PMID:18281713

  15. Lateralization of brain processing in animal/plant categorization task%动植物分类任务中的左侧半球优势

    Institute of Scientific and Technical Information of China (English)

    王培培; 陈昭燃

    2012-01-01

    Objective Categorizing external stimuli in cognitive processing is a basic principle in the brain mechanism. Numerous studies have suggested different brain mechanisms in processing natural vs. Artificial objects. However, few studies have explored the difference in brain mechanism in processing animals and plants, although they play different roles in human evolution. To examine the difference in their processing mechanisms, we employed neuropsychological approach to compare the speed of judgment on nouns belonging to animals or plants. We also examined the relationship between functional lateralization of the brain and the difference in processing animals and plants. Methods Twenty-five right-handed participants (healthy college female subjects, 20 -25 years old) were asked to categorize 120 single-character nouns belong to either animals or plants. The subjects were instructed to respond with speech in one session, and response with button presses in the other two. In the first button-press session, left hand corresponded to animals, and right hand corresponded to plants. The correspondence was switched in the last session. Results In the speech-response session, the reaction time (RT) in responding to animals was significantly shorter than that to plants (t = -3.77, P < 0.001). In the button-press sessions, a significantly faster RT for animals than plants (t = -3. 98,P <0. 001) was observed with the right-hand response. Conclusion Our study provided primary but initial evidence showing the brain mechanisms in processing animals and plants are different. Relationships between the functional lateralization of the brain and the processing mechanisms for animals and plants were also observed.%目的 利用神经心理学方法比较人类对动植物类别的加工速度与大脑功能偏侧化的关系.方法 要求25名右利手被试分别用声音反应和按键反应方式判别刺激属于动物或植物.在按键反应任务中,按左手-动物,右手-植

  16. Feeding distiller’s grains as an energy source to gestating and lactating beef heifers: Impact on female progeny growth, puberty attainment, and reproductive processes.

    Science.gov (United States)

    Gunn, P J; Schoonmaker, J P; Lemenager, R P; Bridges, G A

    2015-02-01

    This study compared postweaning growth, puberty attainment, and reproductive processes of female progeny (n = 33) born to Angus-Simmental beef heifers treated with either a control diet or a diet in which dried distiller’s grains with solubles (DDGS) were fed as an energy source during late gestation and early lactation. From 192 d of gestation through 118 ± 4 d in lactation, dams were fed either a corn silage–based control diet (CON) orcorn residue with DDGS, where DDGS were supplemented as an energy source (DG). Diets were formulated to provide similar daily NEg between diets, but CP requirements were drastically exceeded in the DG treatment. Heifer progeny (n = 33) were weaned, commingled at 191 ± 4 d of age, and similarly managed for the remainder of the project. Heifer BW and blood samples for progesterone assessment to determine onset of puberty were collected weekly beginning at weaning. At 255 ± 4 d of age, a single follicular wave was mapped via ultrasonography in 10 prepubertal heifers per treatment. Prepubertal antral follicle count and ovarian size were determined at 253 ± 4 d of age. Hip height was recorded at 213,297, and 437 ± 4 d of age. Estrous synchronization and AI was initiated at 447 ± 4 d of age. Binary data were analyzed with the GLIMMIX procedures of SAS and all other data were analyzed with the MIXED procedures of SAS. Progeny from DG-treated dams tended to be heavier (P = 0.08) than progeny from CON-treated dams from weaning until breeding. In addition, DG progeny had a greater (P breeding season pregnancy rate did not differ (P = 0.97). Moreover, rate of dystocia in female progeny at first parturition and grand-offspring birth BW did not differ due to treatment (P ≥ 0.74). In summary, feeding DDGS as an energy source during late gestation and early lactation to first-parity heifers resulted in female progeny with greater skeletal growth that were heavier at onset of puberty and had increased AI pregnancy rates. PMID:25548202

  17. NucleoCounter—An efficient technique for the determination of cell number and viability in animal cell culture processes

    OpenAIRE

    Shah, Dimpalkumar; Naciri, Mariam; Clee, Paul; Al-Rubeai, Mohamed

    2006-01-01

    The NucleoCounter is a novel, portable cell counting device based on the principle of fluorescence microscopy. The present work establishes its use with animal cells and checks its reliability, consistency and accuracy in comparison with other cytometric techniques. The main advantages of this technique are its ability to handle a large number of samples with a high degree of precision and its simplicity and specificity in detecting viable cells quantitatively in a heterogeneous culture. The ...

  18. Expression of plasmid DNA in the salivary gland epithelium: novel approaches to study dynamic cellular processes in live animals

    OpenAIRE

    Sramkova, Monika; Masedunskas, Andrius; Parente, Laura; Molinolo, Alfredo; Weigert, Roberto

    2009-01-01

    The ability to dynamically image cellular and subcellular structures in a live animal and to target genes to a specific cell population in a living tissue provides a unique tool to address many biological questions in the proper physiological context. Here, we describe a powerful approach that is based on the use of rat submandibular salivary glands, which offer the possibility to easily perform intravital imaging and deliver molecules from the oral cavity, and plasmid DNA, which offers the a...

  19. Definition of key parameters for constructing an online reference micrographs collection of processed animal particles in feed

    Directory of Open Access Journals (Sweden)

    Belinchon Crespo, C.

    2012-01-01

    Full Text Available The European Union Reference Laboratory for the detection of animal proteins in feedingstuffs (EURL-AP has developed an online micrographs collection supporting its network activities within the European Union for the detection of prohibited animal by-products in feed. So far, the only official method for detecting these by-products is light microscopy, which is highly dependent on the skills of a microscopist because it relies on particle recognition. In order to help the microscopist network to achieve high proficiency levels, it was necessary to create an online reference tool based on micrographs and accessible via an Intranet platform. Members of the National Reference Laboratories for animal proteins in feedingstuffs (NRL-AP and the International Association for Feedingstuff Analysis – Section Feedingstuff Microscopy (IAG have access to this micrographs collection. This paper describes how the online collection was created and what conditions had to be taken into account in creating such a tool. It also describes how information are periodically updated and managed within the context of the large amount of information included in each micrograph. The need for a robust back-office system as the foundation for all the research activities in this project is also covered, and the evaluation of the use of the online collection is discussed.

  20. Subclinical Endometritis Diagnosed through Cytobrush and Reproductive Performance in Cattle from the Municipality of Pupiales, Colombia

    Directory of Open Access Journals (Sweden)

    Darío Antonio Vallejo Timarán

    2014-06-01

    Full Text Available Objective: To determine the distribution of subclinical endometritis and the reproductive behavior of dairy cattle diagnosed through endometrial cytology from the Municipality of Pupiales, Nariño. Materials and methods: A reproductive assessment was carried out (rectal palpation, ultrasonography and evaluation of vaginal mucus to determine the absence of early gestation and of clinical signs of uterine infection, and 174 cows were sampled through cervical catheterization and the technique of Cytobrush starting 30 days after birth. Consequently, the population under study was organized based on ovarian function (empty cycling normal or anestrous and the status of the uterus (with or without endometritis. Results: 43 cows (24.7% showed cellular changes indicative of an active inflammatory process originated in the endometrium. 79.06% of the animals diagnosed with subclinical endometritis were cyclic and had low reproductive performance. Conclusion: The high impact of subclinical endometritis in fertility and reproductive efficiency was determined. An early reproductive assessment must be performed, together with tests that make it possible to determine the presence of concomitant subclinical conditions.

  1. Effects of sexual reproduction of the inferior competitor Brachionus calyciflorus on its fitness against Brachionus angularis

    Science.gov (United States)

    Li, Chen; Niu, Cuijuan

    2015-03-01

    Sexual reproduction adversely affects the population growth of cyclic parthenogenetic animals. The density-dependent sexual reproduction of a superior competitor could mediate the coexistence. However, the cost of sex may make the inferior competitor more vulnerable. To investigate the effect of sexual reproduction on the inferior competitor, we experimentally paired the competition of one Brachionus angularis clone against three Brachionus calyciflorus clones. One of the B. calyciflorus clones showed a low propensity for sexual reproduction, while the other two showed high propensities. The results show that all B. calyciflorus clones were excluded in the competition for resources at low food level. The increased food level promoted the competition persistence, but the clones did not show a clear pattern. Both the cumulative population density and resting egg production increased with the food level. The cumulative population density decreased with the mixis investment, while the resting egg production increased with the mixis investment. A trade-off between the population growth and sexual reproduction was observed in this research. The results indicate that although higher mixis investment resulted in a lower population density, it would not determinately accelerate the exclusion process of the inferior competitor. On the contrary, higher mixis investment promoted resting egg production before being excluded and thus promised a long-term benefit. In conclusion, our results suggest that mixis investment, to some extent, favored the excluded inferior competitor under fierce competition or some other adverse conditions.

  2. Incorporation of genetic technologies associated with applied reproductive technologies to enhance world food production

    Science.gov (United States)

    Animal breeding and reproductive physiology have been closely related throughout the history of animal production science. Artificial insemination provides the best method of increasing the influence of sires with superior genetics to improve production traits. Multiple ovulation embryo transfer (MO...

  3. Reproductive disorder studies using radioimmunoassay (RIA) progesterone on dairy cattle

    International Nuclear Information System (INIS)

    Two intensive systems of husbandry practices, Garut West Java and Yogyakarta Central Java, were chosen for this study. Both areas have been voluntarily made into a pilot farm for the application of RIA progesterone to improve reproductive performance. Five dairy cattle from Garut West Java, which according to Health Extension and Artificial Insemination Technicians anamneses and according to farmers who own the animal, were showing reproductive failure and were selected from those cattle for the study. Other fifteen dairy cattle from Yogyakarta area, with anamneses of having low reproductive performance, were also selected for this study. Milk progesterone sample were collected twice a week for five consecutive weeks period of time to follow the biological reproductive status of every animal, while samples from dairy cattle at Yogyakarta were collected three times post Artificial Insemination (AI) services, as according to Artificial Insemination Database Application (AIDA) procedure, to monitor the failure of AI, success rate of AI, and ovarian activities of the cattle. Result of the study in Garut shows that RIA progesterone indicates that animals need special treatments and most AI failed due to lack of historical information of the dairy cows. RIA progesterone leads to a suggestion that it can be use as a tool to monitor the reproductive disorder, as the recommendation made for those cows to anticipate reproductive disorder overcome the problems. Similar result found in Yogyakarta, which almost 50% of the observed animals failed to AI due to miss-estrus detection. Furthermore, from the RIA for milk progesterone, information of the reproductive disorder figures can be drawn and early suggestion could be made to anticipate losses. Overall, beside the reproductive historical record, RIA progesterone is important tool to be applied in the animal husbandry system in Indonesia as to improve the herd productivity and has an economical value to reduce operational cost

  4. Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age

    DEFF Research Database (Denmark)

    Main, Katharina M; Mortensen, Gerda Krog; Kaleva, Marko M;

    2006-01-01

    Phthalates adversely affect the male reproductive system in animals. We investigated whether phthalate monoester contamination of human breast milk had any influence on the postnatal surge of reproductive hormones in newborn boys as a sign of testicular dysgenesis.......Phthalates adversely affect the male reproductive system in animals. We investigated whether phthalate monoester contamination of human breast milk had any influence on the postnatal surge of reproductive hormones in newborn boys as a sign of testicular dysgenesis....

  5. Animal production and health newsletter. No. 34

    International Nuclear Information System (INIS)

    This issue of the newsletter briefs on forthcoming events and on-going activities of the Joint Division. Active Co-ordinated Research Programmes, training workshops, expert meetings in the fields of animal feed supplementation, animal productivity and reproductive efficiency, and diagnostic methodologies in disease control are highlighted

  6. Animal Intuitions.

    Science.gov (United States)

    Kaebnick, Gregory E

    2016-07-01

    As described by Lori Gruen in the Perspective column at the back of this issue, federally supported biomedical research conducted on chimpanzees has now come to an end in the United States, although the wind-down has taken longer than expected. The process began with a 2011 Institute of Medicine report that set up several stringent criteria that sharply limited biomedical research. The National Institutes of Health accepted the recommendations and formed a committee to determine how best to implement them. The immediate question raised by this transition was whether the IOM restrictions should be extended in some form to other nonhuman primates-and beyond them to other kinds of animals. In the lead article in this issue, Anne Barnhill, Steven Joffe, and Franklin Miller consider the status of other nonhuman primates. PMID:27417859

  7. Animal Farm

    Institute of Scientific and Technical Information of China (English)

    徐蓉蓉

    2015-01-01

    This essayfirst introduce the background of Animal Farm and a brief introduction of the author.Then it discuss three thesis about this novel and briefly discussed about it.At last it give highly review on Animal Farm.

  8. Animal Bites

    Science.gov (United States)

    Wild animals usually avoid people. They might attack, however, if they feel threatened, are sick, or are protecting their ... or territory. Attacks by pets are more common. Animal bites rarely are life-threatening, but if they ...

  9. Animal Bites

    Science.gov (United States)

    ... and complications from bites Never pet, handle, or feed unknown animals Leave snakes alone Watch your children closely around animals Vaccinate your cats, ferrets, and dogs against rabies Spay or neuter ...

  10. Animal Farm

    Institute of Scientific and Technical Information of China (English)

    徐蓉蓉

    2015-01-01

    This essay first introduce the background of Animal Farm and a brief introduction of the author.Then it discuss three thesis about this novel and briefly discussed about it.At last it give highly review on Animal Farm.

  11. Using a Delphi consensus process to develop an acupuncture treatment protocol by consensus for women undergoing Assisted Reproductive Technology (ART) treatment

    OpenAIRE

    Smith Caroline A; Grant Suzanne; Lyttleton Jane; Cochrane Suzanne

    2012-01-01

    Abstract Background Assisted reproductive technologies (ART) are increasingly utilised for resolving difficulties conceiving. These technologies are expensive to both the public purse and the individual consumers. Acupuncture is widely used as an adjunct to ART with indications that it may assist reducing the time to conception and increasing live birth rates. Heterogeneity is high between treatment protocols. The aim of this study was to examine what fertility acupuncturists consider key com...

  12. Investigation on reproduction process in two species of crab Eriphia sebana and Ocypode saratan in the intertidal zone of Chabahar area

    OpenAIRE

    Kazemiyan, Mohammad

    2005-01-01

    The present study with headline investigation on reproduction in two species of crab Eriphia sebana and Ocypode saratan was carried out in the intertidal zone of Chabahar in thirteen month from December 2004 to December 2005. Checked samplings have been taken, 45 number Crab monthly from any four stations by manual or use trap. During this study the following subjects were measured: temperature range and salinity, measurable coast granule, determination of sex ratio, relations carapace width ...

  13. ‘Expanding your mind’: the process of constructing gender-equitable masculinities in young Nicaraguan men participating in reproductive health or gender training programs

    OpenAIRE

    Salazar Torres, Virgilio Mariano; Goicolea, Isabel; Edin, Kerstin; Öhman, Ann

    2012-01-01

    Background: Traditional forms of masculinity strongly influence men’s and women’s wellbeing. Objective: This study has two aims: (i) to explore notions of various forms of masculinities in young Nicaraguan men participating in programs addressing sexual health, reproductive health, and/or gender equality and (ii) to find out how these young men perceive their involvement in actions aimed at reducing violence against women (VAW).Design: A qualitative grounded theory study. Data were collected ...

  14. Animal ethics

    OpenAIRE

    Palmer, Clare; Sandøe, Peter

    2011-01-01

    This chapter describes and discusses different views concerning our duties towards animals. First, we explain why it is necessary to engage in thinking about animal ethics and why it is not enough to rely on feelings alone. Secondly, we present and discuss five different kinds of views about the nature of our duties to animals. They are: contractarianism, utilitarianism, the animal rights view, contextual views, and a respect for nature view. Finally, we briefly consider whether it is possibl...

  15. Quadruped Animation

    OpenAIRE

    Skrba, Ljiljana; Reveret, Lionel; Hétroy, Franck; Cani, Marie-Paule; O'Sullivan, Carol

    2008-01-01

    Films like Shrek, Madagascar, The Chronicles of Narnia and Charlotte's web all have something in common: realistic quadruped animations. While the animation of animals has been popular for a long time, the technical challenges associated with creating highly realistic, computer generated creatures have been receiving increasing attention recently. The entertainment, education and medical industries have increased the demand for simulation of realistic animals in the computer graphics area. In...

  16. Thin Animals

    OpenAIRE

    Johnston, D.

    1998-01-01

    Lattice animals provide a discretized model for the theta transition displayed by branched polymers in solvent. Exact graph enumeration studies have given some indications that the phase diagram of such lattice animals may contain two collapsed phases as well as an extended phase. This has not been confirmed by studies using other means. We use the exact correspondence between the q --> 1 limit of an extended Potts model and lattice animals to investigate the phase diagram of lattice animals ...

  17. The male reproductive system and the effect of an extract of a medicinal plant (Hypericum perforatum) on the labeling process of blood constituents with technetium-99m

    Energy Technology Data Exchange (ETDEWEB)

    Santos-Filho, Sebastiao David [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. de Biologia Roberto Alcantara Gomes. Lab. de Radiofarmacia Experimental; Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil)]. E-mail: santos-filho@uerj.br; Fonseca, Adenilson de Souza da [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. de Biologia Roberto Alcantara Gomes. Lab. de Radiofarmacia Experimental; Bernardo-Filho, Mario [Instituto Nacional do Cancer, Rio de Janeiro, RJ (Brazil). Coordenadoria de Pesquisa

    2007-09-15

    Hypericum perforatum (hiperico) is a plant that has been used to treat diseases and also inhibits rat and human vas deferens contractility. In nuclear medicine, stannous chloride (SnCl{sub 2}) is used as a reducing agent to obtain radiopharmaceuticals labeling with technetium-99m. As the SnCl{sub 2} seems to have adverse effects related with the reproductive performance of male rabbits as well as the human consumption of hiperico might affect sexual function. In the present work, consistent results show significant changes on the blood constituents labeled by technetium-99m obtained from young rats under the effect of an hiperico extract as opposed to blood samples equally treated taken from elderly rat. Supposedly, this extract could protect the male reproductive system against action of SnCl{sub 2} at least in young rats. The findings described in this work allow introducing a simple assay to evaluate the action of products that could interfere with the male reproductive system. (author)

  18. Animal Deliberation

    NARCIS (Netherlands)

    Driessen, C.P.G.

    2014-01-01

    While much has been written on environmental politics on the one hand, and animal ethics and welfare on the other, animal politics, as the interface of the two, is underexamined. There are key political implications in the increase of animal protection laws, the rights of nature, and political parti

  19. Animal models

    DEFF Research Database (Denmark)

    Gøtze, Jens Peter; Krentz, Andrew

    2014-01-01

    In this issue of Cardiovascular Endocrinology, we are proud to present a broad and dedicated spectrum of reviews on animal models in cardiovascular disease. The reviews cover most aspects of animal models in science from basic differences and similarities between small animals and the human...

  20. Multiple reproductive strategies in a tropical hover wasp

    DEFF Research Database (Denmark)

    Fanelli, D.; Boomsma, Jacobus Jan; Turillazzi, S.

    2005-01-01

    occurs in some of the nests. Present reproductive skew theory appears to be at best partly sufficient to account for the observed complexity of social organisation. The observed patterns of colony composition and reproductive sharing are weakly consistent with the hypothesis of reproductive transactions......Reproductive skew theory has been an important component of efforts to design a unifying theory of social evolution, as it aims to explain patterns of reproductive partitioning in animal societies as a function of relatedness, group productivity, fighting ability and ecological constraints on...... sample of colonies of the Stenogastrine wasp Parischnogaster mellyi with a powerful set of DNA microsatellite markers. We show that various apparently stable forms of social organisation co-exist in a single population, and that sharing of reproduction between related and unrelated egg-laying females...

  1. Suppressing subordinate reproduction provides benefits to dominants in cooperative societies of meerkats

    OpenAIRE

    Bell, M. B. V.; Cant, M A; Borgeaud, C.; Thavarajah, N.; Samson, J.; Clutton-Brock, T. H.

    2014-01-01

    In many animal societies, a small proportion of dominant females monopolize reproduction by actively suppressing subordinates. Theory assumes that this is because subordinate reproduction depresses the fitness of dominants, yet the effect of subordinate reproduction on dominant behaviour and reproductive success has never been directly assessed. Here, we describe the consequences of experimentally preventing subordinate breeding in 12 groups of wild meerkats (Suricata suricatta) for three bre...

  2. Life span, reproductive output, and reproductive opportunity in captive Goeldi's monkeys (Callimico goeldii).

    Science.gov (United States)

    Nuss, Kara; Warneke, Mark

    2010-01-01

    In the absence of long-term field studies, demographic and reproductive records from animals housed in zoos and research laboratories are a valuable tool for the study of life history variables relating to reproduction. In this study, we analyzed studbook records of more than 2,000 individuals born over a 40-year period (1965-2004) to describe life history patterns of captive Goeldi's monkeys (Callimico goeldii) housed in North America and Europe. Using Kaplan-Meier survival analysis methods, we found the mean life span to be 5.5 years. The rate of infant mortality, defined as death before 30 days, was approximately 30%, with European animals being more likely to survive infancy than North American animals. When individuals surviving at least 1.5 years are considered, lifetime reproductive output averaged 3.5 offspring, yet more than one-third of individuals did not produce any offspring. Using a smaller dataset of individuals with known pairing histories, we developed a measure of opportunity for reproduction (OFR), which represented the total time an individual was known to be housed with a potential mate. For both sexes, we found that the correlation between OFR and number of offspring produced was much higher than the correlation between life span and number of offspring produced. This result highlights the importance of taking into account an individual's OFR. As a whole, our findings help characterize the life histories of captive Goeldi's monkeys and emphasize the impact management practices may have on reproductive success. PMID:20131357

  3. Entry, Descent, Landing Animation (Animation)

    Science.gov (United States)

    2005-01-01

    [figure removed for brevity, see original site] Click on the image for Entry, Descent, Landing animation This animation illustrates the path the Stardust return capsule will follow once it enters Earth's atmosphere.

  4. Animal research

    DEFF Research Database (Denmark)

    Olsson, I.A.S.; Sandøe, Peter

    2012-01-01

    in science (as in any other human use that is not also in the animals’ best interest). These views are not compatible, and since all three views in more or less pure form are found in modern Western societies, use of animals for research is bound to cause controversy. However, there may be room for some kind......This article presents the ethical issues in animal research using a combined approach of ethical theory and analysis of scientific findings with bearing on the ethical analysis. The article opens with a general discussion of the moral acceptability of animal use in research. The use of animals...... in research is analyzed from the viewpoint of three distinct ethical approaches: contractarianism, utilitarianism, and animal rights view. On a contractarian view, research on animals is only an ethical issue to the extent that other humans as parties to the social contract care about how research animals...

  5. Shift work and circadian dysregulation of reproduction

    Directory of Open Access Journals (Sweden)

    Karen L. Gamble

    2013-08-01

    Full Text Available Health impairments, including reproductive issues, are associated with working nights or rotating shifts. For example, shift work has been associated with an increased risk of irregular menstrual cycles, endometriosis, infertility, miscarriage, low birth weight or pre-term delivery, and reduced incidence of breastfeeding. Based on what is known about circadian regulation of endocrine rhythms in rodents (and much less in humans, the circadian clock is an integral regulatory part of the reproductive system. When this 24-h program is disordered by environmental perturbation (such as shift work or genetic alterations, the endocrine system can be impaired. The purpose of this review is to explore the hypothesis that misalignment of reproductive hormones with the environmental light-dark cycle and/or sleep wake rhythms can disrupt menstrual cycles, pregnancy, and parturition. We highlight the role of the circadian clock in regulating human reproductive physiology and shift work-induced pathology within each step of the reproductive axis while exploring potential mechanisms from the animal model literature. In addition to documenting the reproductive hazards of shift work, we also point out important gaps in our knowledge as critical areas for future investigation. For example, future studies should examine whether forced desynchronization disrupts gonadotropin secretion rhythms and whether there are sleep/wake schedules that are better or worse for the adaptation of the reproductive system to shift work. These studies are necessary in order to define not only whether or not shift-work induced circadian misalignment impairs reproductive capacity, but also to identify strategies for the future that can minimize this desynchronization.

  6. Shift work and circadian dysregulation of reproduction.

    Science.gov (United States)

    Gamble, Karen L; Resuehr, David; Johnson, Carl Hirschie

    2013-01-01

    Health impairments, including reproductive issues, are associated with working nights or rotating shifts. For example, shift work has been associated with an increased risk of irregular menstrual cycles, endometriosis, infertility, miscarriage, low birth weight or pre-term delivery, and reduced incidence of breastfeeding. Based on what is known about circadian regulation of endocrine rhythms in rodents (and much less in humans), the circadian clock is an integral regulatory part of the reproductive system. When this 24-h program is disordered by environmental perturbation (such as shift work) or genetic alterations, the endocrine system can be impaired. The purpose of this review is to explore the hypothesis that misalignment of reproductive hormones with the environmental light-dark cycle and/or sleep-wake rhythms can disrupt menstrual cycles, pregnancy, and parturition. We highlight the role of the circadian clock in regulating human reproductive physiology and shift work-induced pathology within each step of the reproductive axis while exploring potential mechanisms from the animal model literature. In addition to documenting the reproductive hazards of shift work, we also point out important gaps in our knowledge as critical areas for future investigation. For example, future studies should examine whether forced desynchronization disrupts gonadotropin secretion rhythms and whether there are sleep/wake schedules that are better or worse for the adaptation of the reproductive system to shift work. These studies are necessary in order to define not only whether or not shift work-induced circadian misalignment impairs reproductive capacity, but also to identify strategies for the future that can minimize this desynchronization. PMID:23966978

  7. Effects of Ketamine on Context-Processing Performance in Monkeys: A New Animal Model of Cognitive Deficits in Schizophrenia

    OpenAIRE

    Blackman, Rachael K.; MacDonald, Angus W; Chafee, Matthew V

    2013-01-01

    Cognitive deficits are at the crux of why many schizophrenia patients have poor functional outcomes. One of the cognitive symptoms experienced by schizophrenia patients is a deficit in context processing, the ability to use contextual information stored in working memory to adaptively respond to subsequent stimuli. As such, context processing can be thought of as the intersection between working memory and executive control. Although deficits in context processing have been extensively charac...

  8. Technical Notes on Reproductive Health

    OpenAIRE

    Amanda Glassman; Ingvild Belle; Isabel Nieves

    2000-01-01

    These publication is a series of 12 Technical Notes on Reproductive Health. The connections between poverty and reproductive ill health are multidimensional. This publication covers reproductive health, human capital development, reproductive health interventions, public health policies and health sector reform as well as a myriad of other topics concerning reproductive health in Latin America and the Caribbean.

  9. Stress hormones link food availability and population processes in seabirds

    Science.gov (United States)

    Kitaysky, A.S.; Piatt, J.F.; Wingfield, J.C.

    2007-01-01

    Catastrophic population declines in marine top predators in the northern Pacific have been hypothesized to result from nutritional stress affecting reproduction and survival of individuals. However, empirical evidence for food-related stress in wild animals is frequently lacking or inconclusive. We used a field endocrinology approach to measure stress, identify its causes, and examine a link between stress and population processes in the common murre Uria aalge. We tested the empirical relationship between variations in the stress hormone corticosterone (CORT) and food abundance, reproduction, and persistence of individuals at declining and increasing colonies in Cook Inlet, Alaska, from 1996 to 2001. We found that CORT secretion in murres is independent of colony, reproductive stage effects, and gender of individuals, but is directly negatively correlated with abundance of their food. Baseline CORT reflected current food abundance, whereas acute stress-induced CORT reflected food abundance in the previous month. As food supply diminished, increased CORT secretion predicted a decrease in reproductive performance. At a declining colony, increased baseline levels of CORT during reproduction predicted disappearance of individuals from the population. Persistence of individuals in a growing colony was independent of CORT during reproduction. The obtained results support the hypothesis that nutritional stress during reproduction affects reproduction and survival in seabirds. This study provides the first unequivocal evidence for CORT secretion as a mechanistic link between fluctuations in food abundance and population processes in seabirds. ?? Inter-Research 2007.

  10. Diagnostic and control functions of the radioisotope methods for the reproduction management of cattle and sheep breeding

    International Nuclear Information System (INIS)

    The following applications of radioimmunoassay were studied: 1) for early diagnosis of pregnance in caws and sheep by determination of progesterone (PG) in milk and blood plasma via veterinary radioimmunological test STERON - RM125; 2) for diagnosis and treatment of ovarian disturbances in cows by RIA of luteinizing hormone (LH), follicle stimulating hormone (FSH) and PG in blood plasma; 3) for control of the biological efficiency of sheep estrus synchronisation with MAP (vaginal tampons) and Estrophan (PgF2α); 4) for control of the reproductive condition of rams and effect of Tribestan in treatment of different forms of impotention by RIA of testosterone in blood. It was established that the use of RIA objectified the process of decision-making in regulation of the reproduction deviations in ruminating farm animals by veterinary means. Conclusions are drawn and suppositions are made for introduction of the radioisotope methods in the reproduction control of cattle and sheep breeding in practice. 4 tabs.; 15 refs

  11. What we know about the genetics of reproduction

    Science.gov (United States)

    Animal breeding and reproductive physiology have been closely related throughout the history of animal production science, because artificial insemination provides the best method of increasing the influence of sires with superior genetics to improve production traits. The addition of genetic techn...

  12. Genetics of reproductive traits: Antagonisms with production traits

    Science.gov (United States)

    Animal breeding and reproductive physiology have been closely related throughout the history of animal production science, because artificial insemination provides the best method of increasing the influence of sires with superior genetics to improve production traits. The addition of genetic techn...

  13. [Transgenic animals and animal welfare

    Science.gov (United States)

    Reinhardt, Christoph

    1998-01-01

    Under the pressure of a public vote in Switzerland (7 June 1998) on an initiative to ban the production, use and patenting of transgenic animals, their value for biomedical research and development is intensely debated. In addition, the Swiss legislation has adopted (1992) a constitutional obligation to "take into account the dignity of creatures". The term "dignity of creatures", however, can be interpreted in anthropocentric or biocentric ways. The government has now formulated the legal implications of this term for transgenic animals and plants in various laws including the animal and environmental protection laws. This paper gives arguments for a fair evaluation of trangenic animals from an animal welfare point of view where not only the costs of animal suffering must be considered but also the probability of potential benefit for man. A self-confident research community should allow such an evaluation procedure even in view of an outcome which could ban many uses of transgenic animals PMID:11208266

  14. Spermatogonial stem cells: Current biotechnologicaladvances in reproduction and regenerative medicine

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Spermatogonial stem cells (SSCs) are the germ stemcells of the seminiferous epithelium in the testis.Through the process of spermatogenesis, they producesperm while concomitantly keeping their cellular poolconstant through self-renewal. SSC biology offersimportant applications for animal reproduction andovercoming human disease through regenerativetherapies. To this end, several techniques involvingSSCs have been developed and will be covered inthis article. SSCs convey genetic information to thenext generation, a property that can be exploited forgene targeting. Additionally, SSCs can be induced tobecome embryonic stem cell-like pluripotent cells invitro . Updates on SSC transplantation techniques withrelated applications, such as fertility restoration andpreservation of endangered species, are also covered onthis article. SSC suspensions can be transplanted to thetestis of an animal and this has given the basis for SSCfunctional assays. This procedure has proven technicallydemanding in large animals and men. In parallel, testistissue xenografting, another transplantation technique,was developed and resulted in sperm production intestis explants grafted into ectopical locations in foreignspecies. Since SSC culture holds a pivotal role in SSCbiotechnologies, current advances are overviewed.Finally, spermatogenesis in vitro , already demonstratedin mice, offers great promises to cope with reproductiveissues in the farm animal industry and human clinicalapplications.

  15. Physiological and biochemical changes of females of Piracanjuba, subjected to induced reproduction.

    Science.gov (United States)

    Zanoni, M A; Costa, F G; de Carvalho, S; Seiva, F R F

    2016-08-01

    The aim of this experiment was to compare the level of fish female stress during induced reproduction with pituitary extract by two different methods, natural and semiextruded. The reproductive efficiency was 62.5% in the seminatural treatment and 100% in the extruded. Obtained egg volume was 5200 ml and 4000 ml, for seminatural and extruded treatments respectively. The mean number of eggs was 46.7 for the seminatural and 52.0 and for the extruded treatment. The percentage of viable eggs was, respectively, 87.2% and 8.17% for the natural treatment and extruded semimethods. Blood samples were collected to quantify cortisol and glucose levels, as well as red cell series and lymphocyte count. Fishes submitted to induction procedures showed elevated cortisol and glucose levels, compared to the control animals. The results for haematocrit, haemoglobin concentration and red blood cell count showed no significant differences among groups. Significant differences found in the number of lymphocytes and monocytes suggest the general adaptation syndrome. Our results suggest the reproductive induction process with extrusion of gametes as a more stressful method than seminatural reproduction process. PMID:26719107

  16. Improving the reproductive management of smallholder dairy cattle and the effectiveness of artificial insemination: A summary

    International Nuclear Information System (INIS)

    Economic development is progressing rapidly in Asia. One of the many consequences of this phenomenon is an increased demand for food arising from animal agriculture. This increased demand for animal products creates the possibility for a greater dispersion of economic resources, which to this point has been largely confined to urban areas. Thus, the opportunity for poverty alleviation in rural areas exists, but obstacles to this process must be removed. A high priority of the member states of the RCA (Regional Cooperative Agreement for Asia and the Pacific) is thus to support research and the adoption of technologies that can help overcome these obstacles. Ironically, population expansion, although increasing demand, can have a net negative effect on livestock farming, by restricting the amount of land available for raising animals. Therefore, one major focus on increasing production of animal products must be the increase in productivity per animal and per unit of land. Improvement of nutrition is an important strategy for improving the output of livestock production and results can be obtained in the short-term. On the other hand, selective breeding is a highly effective and sustainable approach for increasing animal productivity in the long-term. Reproductive technologies such as artificial insemination (AI) allow single animals to have multiple progeny, reducing the number of parent animals required and allowing for significant increases in the intensity of selection, and proportional increases in genetic improvement of production

  17. CONTROL OF REPRODUCTION

    Science.gov (United States)

    Control of reproduction is important for seed stock production, selective breeding, growth rate, feed efficiency, meat quality, and biosecurity. These needs to control reproduction differ among cultivars and even segments of the same industry. No matter the impetus for aquaculturists to want to alte...

  18. Reproductive Physiology of Marsupials

    Science.gov (United States)

    Sharman, G. B.

    1970-01-01

    Describes some unique features of marsupial reproduction which include (1) chromosomal sex determination, (2) reproductive system, (3) birth, (4) location, and (5) embryonic diapause. These features suggest that viviparity evolved separately in eutherian and marsupial stocks after their derivation from a common oviparous ancestor. Bibliography.…

  19. The Reproduction of Intelligence

    Science.gov (United States)

    Meisenberg, Gerhard

    2010-01-01

    Although a negative relationship between fertility and education has been described consistently in most countries of the world, less is known about the relationship between intelligence and reproductive outcomes. Also the paths through which intelligence influences reproductive outcomes are uncertain. The present study uses the NLSY79 to analyze…

  20. Reproduction and Distribution.

    Science.gov (United States)

    Greer, Michael

    1989-01-01

    This latest in a series of articles on the manager's role in an instructional design project highlights techniques for managing the reproduction and distribution of materials. Guidelines for orienting staff are suggested, a sample reproduction and distribution schedule is given, and a storage and distribution system is discussed. (LRW)

  1. Reproduction, Physiology and Biochemistry

    Science.gov (United States)

    This chapter focuses on the reproduction, physiology, and biochemistry of the root-knot nematodes. The extensive amount of information on the reproduction and cytogenetics of species of Meloidogyne contrasts with the limited information on physiology, biochemistry, and biochemical pathways. In commo...

  2. Animal Shelter

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Beijing activist Zhang Luping gives up a lucrative business career to provide a home for stray and abandoned pets "I have never been married, but I have I hundreds of children," said Zhang Luping, founder of the Beijing Human and Animal Environment Education Center (the Animal Center). "God sent me to this planet and gave me the mission of taking care of helpless and homeless dogs and cats. I will never let Him down." The Animal Center, one of a few non-

  3. Reproductive senescence, fertility and reproductive tumour profile in ageing female Han Wistar rats.

    Science.gov (United States)

    Mitchard, Terri L; Klein, Stephanie

    2016-01-01

    A study using vehicle administration in 104 female rats investigated reproductive aging in Han Wistar rats as a useful tool to interprete carcinogenicity studies where hormonal patterns are perturbated. From 16 weeks of age oestrous cycles were monitored every 6 weeks to investigate reproductive ageing. A subset of 20 females was used to assess fertility at 21 months of age. The animals were necropsied after 106-107 weeks on study and female reproductive organs, mammary glands and pituitary glands were examined for hyperplasias and/or tumours. The majority of rats had regular oestrous cycles up to 6 months of age. After this age, there was a rapid decline in the number of rats with regular oestrous cycles and an increase in irregular cycles and cycles in persistent di-oestrus with an occasional pro-oestrus. By the end of the study, the majority of animals were acyclic and the few remaining cyclic animals had irregular cycles. In the fertility assessment, 19/20 animals mated but only four animals became pregnant. These pregnant animals had normal numbers of corpora lutea of pregnancy but had high pre-implantation losses and could not sustain a viable pregnancy. 65 animals (62.5%) showed adenomas and/or pituitary hyperplasia in the pituitary gland at necropsy. The pituitary tumours were likely to be prolactin secreting that give rise to pseudopregnancy and mammary tumours, demonstrated by the fact that 43/65 (66%) of the affected animals had histopathological signs of these conditions. Multiple corpora lutea were found in 61% of all animals at time of termination. Only one uterine tumour was seen in this study probably due to lack of persistent oestrus seen in these animals. PMID:26655996

  4. Neuropeptidomics applied to studies of mammalian reproduction

    OpenAIRE

    Le Thao T.; Lehnert Sigrid; Colgrave Michelle L

    2014-01-01

    Neuropeptidomics, a mass spectrometry-based technique which aims to uncover the complete suite of neuropeptides present in a tissue, organ or cell from the brain or nervous system, has found application in studies examining physiological responses (e.g. food intake, appetite and reproduction). Neuropeptides (and peptide hormones) have long been known as regulators of mammalian physiological processes, particularly reproduction. These peptides are derived from precursor proteins and become act...

  5. Endangered Animals. Second Grade.

    Science.gov (United States)

    Popp, Marcia

    This second grade teaching unit centers on endangered animal species around the world. Questions addressed are: What is an endangered species? Why do animals become extinct? How do I feel about the problem? and What can I do? Students study the definition of endangered species and investigate whether it is a natural process. They explore topics…

  6. Society for Assisted Reproductive Technology

    Science.gov (United States)

    The Society for Assisted Reproductive Technology PATIENTS Patient Information What Is SART? Risks of IVF Third Party Reproduction A ... Read Article View All News ©1996 - 2016 SART, Society for Assisted Reproductive Technology . All Rights Reserved. ASRM/ ...

  7. Persistent organic pollutants and male reproductive health

    DEFF Research Database (Denmark)

    Vested, Anne; Giwercman, Aleksander; Bonde, Jens Peter;

    2014-01-01

    Environmental contaminants such as persistent organic pollutants (POPs) are man-made bioaccumulative compounds with long half-lives that are found throughout the world as a result of heavy use in a variety of consumer products during the twentieth century. Wildlife and animal studies have long...... suggested adverse effects of exposure to these compounds on human reproductive health, which, according to the endocrine disrupter hypothesis, are ascribed to the compounds' potential to interfere with endocrine signaling, especially when exposure occurs during certain phases of fetal and childhood...... development. An extensive number of epidemiological studies have addressed the possible effects of exposure to POPs on male reproductive health, but the results are conflicting. Thus far, most studies have focused on investigating exposure and the different reproductive health outcomes during adulthood. Some...

  8. Reproductive Behaviour Of Timor Deer (Rusa Timorensis

    Directory of Open Access Journals (Sweden)

    Daud Sansudewa

    2011-09-01

    Full Text Available Timor deer (Rusa timorensis is a newly domesticated animal in Indonesia and other countries in the world. It is a potential source of meat and livelihood. Low birth rate is a problem of deer farming in Indonesia. It happens because of low concern for key aspects of behaviors including reproductive behavior. The aim of this review is to give information about reproductive behavior of Timor deer in natural habitat and captivity breeding. Libido and estrous behaviors of Timor deer in captivity breeding were similar with natural habitat. However, male Timor deer in captivity breeding took longer time to approach the females before mating, compared with those in their natural habitat. Aggressive behavior commonly leads mating. Parturition and maternal behavior of hinds are affected by limitation of space, therefore dividing the area of cage which depends on age and physiological status is needed to improve reproductive management.

  9. Animal ethics

    DEFF Research Database (Denmark)

    Palmer, Clare; Sandøe, Peter

    2011-01-01

    This chapter describes and discusses different views concerning our duties towards animals. First, we explain why it is necessary to engage in thinking about animal ethics and why it is not enough to rely on feelings alone. Secondly, we present and discuss five different kinds of views about...... the nature of our duties to animals. They are: contractarianism, utilitarianism, the animal rights view, contextual views, and a respect for nature view. Finally, we briefly consider whether it is possible to combine elements from the presented views, and how to make up one’s mind....

  10. Use of glucose consumption rate (GCR) as a tool to monitor and control animal cell production processes in packed-bed bioreactors.

    Science.gov (United States)

    Meuwly, F; Papp, F; Ruffieux, P-A; Bernard, A R; Kadouri, A; von Stockar, U

    2006-03-01

    For animal cell cultures growing in packed-bed bioreactors where cell number cannot be determined directly, there is a clear need to use indirect methods that are not based on cell counts in order to monitor and control the process. One option is to use the glucose consumption rate (GCR) of the culture as an indirect measure to monitor the process in bioreactors. This study was done on a packed-bed bioreactor process using recombinant CHO cells cultured on Fibra-Cel disk carriers in perfusion mode at high cell densities. A key step in the process is the switch of the process from the cell growth phase to the production phase triggered by a reduction of the temperature. In this system, we have used a GCR value of 300 g of glucose per kilogram of disks per day as a criterion for the switch. This paper will present results obtained in routine operations for the monitoring and control of an industrial process at pilot-scale. The process operated with this GCR-based strategy yielded consistent, reproducible process performance across numerous bioreactor runs performed on multiple production sites. PMID:16153735

  11. Assisted reproductive travel: UK patient trajectories.

    Science.gov (United States)

    Hudson, Nicky; Culley, Lorraine

    2011-11-01

    Media reporting of 'fertility tourism' tends to portray those who travel as a cohesive group, marked by their desperation and/or selfishness and propensity towards morally questionable behaviour. However, to date little has been known about the profile of those leaving the UK for treatment. This paper discusses the first UK-based study of patient assisted reproduction travel that was designed to explore individual travel trajectories. It is argued that existing ways of conceptualizing cross-border reproductive care as 'fertility or reproductive tourism' are in danger of essentializing what the data suggest are diverse, complex and often ambiguous motivations for reproductive travel. The concept of seriality is used to suggest that, whilst 'reproductive tourists' share some characteristics, they also differ in significant ways. This paper argues that, through an examination of the personal landscapes of fertility travel, the diverse processes involved in reproductive travel can be better understood and policymakers can be assisted to avoid what might be regarded as simplistic responses to cross-border reproductive care. PMID:21958915

  12. Small Animal Retinal Imaging

    Science.gov (United States)

    Choi, WooJhon; Drexler, Wolfgang; Fujimoto, James G.

    Developing and validating new techniques and methods for small animal imaging is an important research area because there are many small animal models of retinal diseases such as diabetic retinopathy, age-related macular degeneration, and glaucoma [1-6]. Because the retina is a multilayered structure with distinct abnormalities occurring in different intraretinal layers at different stages of disease progression, there is a need for imaging techniques that enable visualization of these layers individually at different time points. Although postmortem histology and ultrastructural analysis can be performed for investigating microscopic changes in the retina in small animal models, this requires sacrificing animals, which makes repeated assessment of the same animal at different time points impossible and increases the number of animals required. Furthermore, some retinal processes such as neurovascular coupling cannot be fully characterized postmortem.

  13. Animal cytomegaloviruses.

    OpenAIRE

    Staczek, J.

    1990-01-01

    Cytomegaloviruses are agents that infect a variety of animals. Human cytomegalovirus is associated with infections that may be inapparent or may result in severe body malformation. More recently, human cytomegalovirus infections have been recognized as causing severe complications in immunosuppressed individuals. In other animals, cytomegaloviruses are often associated with infections having relatively mild sequelae. Many of these sequelae parallel symptoms associated with human cytomegalovir...

  14. ANIMAL code

    International Nuclear Information System (INIS)

    This report describes ANIMAL, a two-dimensional Eulerian magnetohydrodynamic computer code. ANIMAL's physical model also appears. Formulated are temporal and spatial finite-difference equations in a manner that facilitates implementation of the algorithm. Outlined are the functions of the algorithm's FORTRAN subroutines and variables

  15. Kindergarten Animation

    Science.gov (United States)

    Hinshaw, Craig

    2012-01-01

    Animation is one of the last lessons that come to mind when thinking of kindergarten art. The necessary understanding of sequencing, attention to small, often detailed drawings, and the use of technology all seem more suitable to upper elementary. With today's emphasis on condensing and integrating curriculum, consider developing animation lessons…

  16. Evaluation of pre-PCR processing approaches for enumeration of Salmonella enterica in naturally contaminated animal feed

    DEFF Research Database (Denmark)

    Schelin, Jenny; Andersson, Gunnar; Vigre, Håkan;

    2014-01-01

    Three pre‐PCR processing strategies for the detection and/or quantification of Salmonella in naturally contaminated soya bean meal were evaluated. Methods included: (i) flotation‐qPCR [enumeration of intact Salmonella cells prior to quantitative PCR (qPCR)], (ii) MPN‐PCR (modified most probable n...

  17. Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals

    NARCIS (Netherlands)

    Arendt, T; Stieler, J; Strijkstra, AM; Hut, RA; Rudiger, J; Van der Zee, EA; Harkany, T; Holzer, M; Hartig, W; Härtig, Wolfgang

    2003-01-01

    Neurofibrillary pathology [ paired helical filaments (PHFs)] formed by the microtubule-associated protein tau in a hyperphosphorylated form is a major hallmark of Alzheimer's disease and related disorders. The process of tau phosphorylation, thought to be of critical importance for PHF formation, an

  18. Animal production and health newsletter. No. 20

    International Nuclear Information System (INIS)

    The activities of the Animal Production and Health Section of the Joint FAO/IAEA Division are carried out through the operation of Co-ordinated Research Programmes and Technical Co-operation projects, both of which aim to encourage and improve the capacity of national institutions in tropical and subtropical countries to identify and resolve problems connected with livestock development. This particular programme at the outset, it was envisaged that an inter-disciplinary approach would be adopted by each participating institute whereby studies on nutrition, reproduction and health would be integrated into a number of site specific projects. The one discussed in this newsletter covers animal production and focussing on animal reproduction and reproduction-nutrition interactions. This paper contains an outline for the program which encourages scientists from universities and research institutes to provide assistance and solutions to developing countries on the technical difficulties associated with artificial insemination

  19. Hermaphroditism in some marine animals

    OpenAIRE

    Kagwade, P.V.

    1988-01-01

    Hermaphroditism, a phenomenon in which one and the same individual produces sperms, the male gamate the ovum, the female gamate, is generally common in plants and lower animals and hence is considered as a primitive character. However, it is rare in higher invertebrates such as insects, spiders, prawns and also in the lower vertebrates to which fishes belong. Prawns and fishes have highly evolved reproductive systems and occur as separate individuals of males and females. Both these groups do...

  20. The male reproductive system and the effect of an extract of a medicinal plant (Hypericum perforatum on the labeling process of blood constituents with technetium-99m

    Directory of Open Access Journals (Sweden)

    Sebastião David Santos-Filho

    2007-09-01

    Full Text Available Hypericum perforatum (hiperico is a plant that has been used to treat diseases and also inhibits rat and human vas deferens contractility. In nuclear medicine, stannous chloride (SnCl2 is used as a reducing agent to obtain radiopharmaceuticals labeling with technetium-99m. As the SnCl2 seems to have adverse effects related with the reproductive performance of male rabbits as well as the human consumption of hiperico might affect sexual function. In the present work, consistent results show significant changes on the blood constituents labeled by technetium-99m obtained from young rats under the effect of an hiperico extract as opposed to blood samples equally treated taken from elderly rat.. Supposedly, this extract could protect the male reproductive system against action of SnCl2 at least in young rats. The findings described in this work allow introducing a simple assay to evaluate the action of products that could interfere with the male reproductive system.Hypericum perforatum (hiperico tem sido utilizado para tratar diferentes distúrbios e também inibir a contractilidade do ducto deferente em ratos e em humanos. Na medicina nuclear, o cloreto estanoso (SnCl2 é usado como um agente redutor para obter radiofármacos marcados com tecnécio-99m. Como o SnCl2 parece acarretar efeitos indesejáveis relacionados com o desempenho reprodutivo de coelhos machos e o hiperico pode afetar a função sexual em humanos, o objetivo desse trabalho é apresentar resultados sobre o efeito de um extrato de hiperico na marcação de constituintes sangüíneos com o tecnécio-99m retirados de ratos jovens e idosos. O hiperico parece alterar a marcação de constituintes sangüíneos com tecnécio-99m isolados de sangue de animais jovens. Embora, esse resultado não seja observado em ratos idosos. Provavelmente, o extrato poderia apresentar uma ação protetora para o sistema reprodutivo contra a ação do SnCl2, pelo menos em ratos jovens. Os resultados

  1. Arsenic Toxicity in Male Reproduction and Development.

    Science.gov (United States)

    Kim, Yoon-Jae; Kim, Jong-Min

    2015-12-01

    Arsenic is a toxic metalloid that exists ubiquitously in the environment, and affects global health problems due to its carcinogenicity. In most populations, the main source of arsenic exposure is the drinking water. In drinking water, chronic exposure to arsenic is associated with increased risks of various cancers including those of skin, lung, bladder, and liver, as well as numerous other non-cancer diseases including gastrointestinal and cardiovascular diseases, diabetes, and neurologic and cognitive problems. Recent emerging evidences suggest that arsenic exposure affects the reproductive and developmental toxicity. Prenatal exposure to inorganic arsenic causes adverse pregnancy outcomes and children's health problems. Some epidemiological studies have reported that arsenic exposure induces premature delivery, spontaneous abortion, and stillbirth. In animal studies, inorganic arsenic also causes fetal malformation, growth retardation, and fetal death. These toxic effects depend on dose, route and gestation periods of arsenic exposure. In males, inorganic arsenic causes reproductive dysfunctions including reductions of the testis weights, accessory sex organs weights, and epididymal sperm counts. In addition, inorganic arsenic exposure also induces alterations of spermatogenesis, reductions of testosterone and gonadotrophins, and disruptions of steroidogenesis. However, the reproductive and developmental problems following arsenic exposure are poorly understood, and the molecular mechanism of arsenic-induced reproductive toxicity remains unclear. Thus, we further investigated several possible mechanisms underlying arsenic-induced reproductive toxicity. PMID:26973968

  2. Reproductive activity and welfare of rabbit does

    Directory of Open Access Journals (Sweden)

    C. Castellini

    2010-04-01

    Full Text Available This paper reviews the relationships between reproductive performance and welfare of the rabbit does. In the last 10 years the profitability of rabbit farms has increased mainly due to improvements in management and genetic selection but several problems mainly related to animal welfare have also occurred. The mortality and rates of female replacement per year are very high and the replaced females often show poor body condition and low performance. The effect of kindling order, litter size, genetic strain, weaning age and reproduction rhythm on the reproductive performance and welfare of females and some mechanisms implicated in these effects are discussed. Modern rabbit does produce a lot of milk which have a high energetic value which leads to a mobilization of body fat which results in an energy deficit. In the current reproductive rhythms, there is an extensive overlap between lactation and gestation. The resulting energetic and hormonal antagonism reduces the fertility rate and lifespan of the doe. Strategies to improve the fertility, lifespan and welfare of does are discussed. An approach which combines various strategies seems to be required to meet these objectives. Since the factors involved in this productive system are fixed (genetic strain, environment the most powerful way to improve doe welfare is to choose a reproductive rhythm that is adapted to the physiology of the does.

  3. Vitamin D - roles in women's reproductive health?

    Directory of Open Access Journals (Sweden)

    Grundmann Magdalena

    2011-11-01

    Full Text Available Abstract In the past few years a growing interest in vitamin D can be observed in the lay and biomedical literature due to findings demonstrating a low vitamin D status in the population. In addition to its importance for the regulation of calcium and phosphorus homeostasis recent epidemiologic studies have observed relationships between low vitamin D levels and multiple disease states. This secosteroid hormone also regulates the expression of a large number of genes in reproductive tissues implicating a role for vitamin D in female reproduction. In this report we summarize the recent evidence that vitamin D status influences female reproductive and pregnancy outcomes. Human and animal data suggest that low vitamin D status is associated with impaired fertility, endometriosis and polycystic ovary syndrome. Evidence from observational studies shows higher rates of preeclampsia, preterm birth, bacterial vaginosis and gestational diabetes in women with low vitamin D levels. However, confirmation of experimental observations establishing an association of vitamin D deficiency with adverse reproductive outcomes by high quality observational and large-scale randomized clinical trials is still lacking. The determination of optimal 25(OHD3 levels in the reproductive period and the amount of vitamin D supplementation required to achieve those levels for the numerous actions of vitamin D throughout a woman's life would have important public health implications.

  4. The politics of reproduction.

    Science.gov (United States)

    Ginsburg, F; Rapp, R

    1991-01-01

    The topic of human reproduction encompasses events throughout the human and especially female life-cycle as well as ideas and practices surrounding fertility, birth, and child care. Most of the scholarship on the subject, up through the 1960s, was based on cross-cultural surveys focused on the beliefs, norms, and values surrounding reproductive behaviors. Multiple methodologies and subspecialties, and fields like social history, human biology, and demography were utilized for the analysis. The concept of the politics of reproduction synthesizes local and global perspectives. The themes investigated include: the concept of reproduction, population control, and the internationalization of state and market interests (new reproductive technologies); social movements and contested domains; medicalization and its discontents; fertility and its control; adolescence and teen pregnancy; birth; birth attendants; the construction of infancy and the politics of child survival; rethinking the demographic transition; networks of nurturance; and meanings of menopause. The medicalization of reproduction is a central issue of studies of birth, midwifery, infertility, and reproductive technologies. Scholars have also analyzed different parts of the female life-cycle as medical problems. Other issues worth analysis include the internationalization of adoption and child care workers; the crisis of infertility of low-income and minority women who are not candidates for expensive reproductive technologies; the concerns of women at high risk for HIV whose cultural status depends on their fertility; questions of reproduction concerning, lesbians and gay men (artificial insemination and discrimination in child rearing); the study of menopause; and fatherhood. New discourse analysis is used to analyze state eugenic policies; conflicts over Western neocolonial influences in which women's status as childbearers represent nationalist interests; fundamentalist attacks on abortion rights; and

  5. The role of social and ecological processes in structuring animal populations: a case study from automated tracking of wild birds

    OpenAIRE

    Farine, Damien R.; Firth, Josh A.; Aplin, Lucy M.; Crates, Ross A.; Culina, Antica; Garroway, Colin J.; Hinde, Camilla A; Kidd, Lindall R.; Milligan, Nicole D.; Psorakis, Ioannis; Radersma, Reinder; Verhelst, Brecht; Voelkl, Bernhard; Sheldon, Ben C.

    2015-01-01

    Both social and ecological factors influence population process and structure, with resultant consequences for phenotypic selection on individuals. Understanding the scale and relative contribution of these two factors is thus a central aim in evolutionary ecology. In this study, we develop a framework using null models to identify the social and spatial patterns that contribute to phenotypic structure in a wild population of songbirds. We used automated technologies to track 1053 individuals...

  6. Membrane progesterone receptors in reproduction and cancer.

    Science.gov (United States)

    Valadez-Cosmes, Paulina; Vázquez-Martínez, Edgar Ricardo; Cerbón, Marco; Camacho-Arroyo, Ignacio

    2016-10-15

    Progesterone is a sexual steroid hormone that has a critical role in reproductive processes in males and females of several species, including humans. Furthermore, progesterone has been associated with pathological diseases such as breast, gynecological and brain cancer, regulating cell proliferation, apoptosis, and metastasis. In the past, progesterone actions were thought to be only mediated by its intracellular receptor (PR). However, recent evidence has demonstrated that membrane progesterone receptors (mPRs) mediate most of the non-classical progesterone actions. The role of the different mPRs subtypes in progesterone effects in reproduction and cancer is an emerging and exciting research area. Here we review studies to date regarding mPRs role in reproduction and cancer and discuss their functions and clinical relevance, suggesting mPRs as putative pharmacological targets and disease markers in cancer and diseases associated with reproduction. PMID:27368976

  7. Reproductive prognosis in endometriosis

    DEFF Research Database (Denmark)

    Hjordt Hansen, Maj V; Dalsgaard, Torur; Hartwell, Dorthe;

    2014-01-01

    OBJECTIVE: To assess the reproductive long-term prognosis of women with and without endometriosis, to explore changes over time, and to quantify the contribution of artificial reproductive techniques. DESIGN: Cohort study. SETTING: Denmark 1977-2009. SAMPLE: Data retrieved from four national...... registries. Among 15-49-year-old women during the period 1977-82, 24 667 were diagnosed with endometriosis and 98 668 (1:4) women without endometriosis were age-matched. METHODS: To assess long-term reproductive prognosis, all pregnancy outcomes were identified among the women with and without endometriosis...

  8. Animal learning.

    Science.gov (United States)

    Castro, Leyre; Wasserman, Edward A

    2010-01-01

    Pavlov and Thorndike pioneered the experimental study of animal learning and provided psychologists with powerful tools to unveil its underlying mechanisms. Today's research developments and theoretical analyses owe much to the pioneering work of these early investigators. Nevertheless, in the evolution of our knowledge about animal learning, some initial conceptions have been challenged and revised. We first review the original experimental procedures and findings of Pavlov and Thorndike. Next, we discuss critical research and consequent controversies which have greatly shaped animal learning theory. For example, although contiguity seemed to be the only condition that is necessary for learning, we now know that it is not sufficient; the conditioned stimulus (CS) also has to provide information about the occurrence of the unconditioned stimulus (US). Also, animals appear to learn different things about the same stimuli when circumstances vary. For instance, when faced with situations in which the meaning of a CS changes, as in the case of acquisition and later extinction, animals seem to preserve the original knowledge (CS-US) in addition to learning about the new conditions (CS-noUS). Finally, we discuss how parallels among Pavlovian conditioning, operant conditioning, and human causal judgment suggest that causal knowledge may lie at the root of both human and animal learning. All of these empirical findings and theoretical developments prove that animal learning is more complex and intricate than was once imagined. Copyright © 2009 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website. PMID:26272842

  9. Reproductive activity and welfare of rabbit does

    OpenAIRE

    Castellini, C.

    2010-01-01

    This paper reviews the relationships between reproductive performance and welfare of the rabbit does. In the last 10 years the profitability of rabbit farms has increased mainly due to improvements in management and genetic selection but several problems mainly related to animal welfare have also occurred. The mortality and rates of female replacement per year are very high and the replaced females often show poor body condition and low performance. The effect of kindling order, litter size, ...

  10. Diverse pollinator communities enhance plant reproductive success

    OpenAIRE

    Albrecht, Matthias; Schmid, Bernhard; Hautier, Yann; Müller, Christine B.

    2012-01-01

    Understanding the functional consequences of biodiversity loss is a major goal of ecology. Animal-mediated pollination is an essential ecosystem function and service provided to mankind. However, little is known how pollinator diversity could affect pollination services. Using a substitutive design, we experimentally manipulated functional group (FG) and species richness of pollinator communities to investigate their consequences on the reproductive success of an obligate out-crossing model p...

  11. Reproductive physiology of the alpaca

    International Nuclear Information System (INIS)

    The alpaca and llama are considered to be seasonally reproductive (from December to March) and given good feeding conditions are reproductively active throughout the year. The males reach puberty at the age of about 2 years when they are free from peno-preputial adhesions. Puberty in the females is affected by body weight and may be reached at the age of 12 months. The females do not have sexual cycles but follicular waves, therefore oestrus varies from 2 to 36 days. Copulation takes place in a seated position and lasts from 5 to 50 minutes; ovulation is induced by coitus, hCG, GnRH and the semen of the alpaca and the bull. 'Spontaneous' ovulation has been observed at the height of the reproductive season and is caused by mechanisms which are not well defined. Multiple ovulation occurs in 10% of females but the number of multiple births is very low. The corpus luteum (CL) forms after mating, attaining maximum size and having the greatest secretory activity on day 9(14.0 nmol/L); it lasts for the 11 months of gestation. If there is no pregnancy, shrinkage of the corpus luteum begins between days 10 and 13 and the progesterone levels fall rapidly. The incidence of embryonic mortality during the first two months of gestation is high. Gestation lasts approximately 342 days, and 93.5% of births occur during the daytime when the environmental conditions are favourable for the newborn animal. The placenta is diffuse and epitheliochorial. Uterine involution is completed within 20 days after birth. Intra- and inter-specific artificial insemination tests have been carried out with intra-uterinal implantation of semen. Embryonic transplant tests have also been conducted. (author)

  12. “三维动画项目流程控制”要点综述%Discussion on "3D animation project process control"

    Institute of Scientific and Technical Information of China (English)

    林喆

    2014-01-01

    从实际项目制作角度出发,阐述了“三维动画创作”的要点,力图理清“三维动画创作”流程控制与管理的基本脉络。从功能划分、进度安排、渲染方案、项目分工四个方面进行了细致说明,论述其重点问题,揭示科学合理的流程控制对于三维动画创作的重要性。建议在制作中不断探索、调整,寻找最适合实际情况的创作思路。%In view of the actual project, the key points of "3D animation creation" are discussed. The process control and the basic venation of management have been expounded. Four aspects including the functional division, the arrangement of scheduling, rendering scheme and project arrangement are discussed. The core problems are introduced. The importance of a scientific and reasonable process control for the three dimensional animation creation are revealed. Incessant exploration, adjustment and searching the most suitable for the actual situation of creative mode in designing are recommended.

  13. Wild Animals

    Institute of Scientific and Technical Information of China (English)

    宁静

    2005-01-01

    Many of us think that all wild animals are dangerous. In fact, very few of them will eat a man if he leaves them alone. If you meet a tiger, I'm sure you will run away, but even a tiger doesn't like meeting a man if it isn't hungry. Tigers only kill and eat man when they are too old to catch their food, such as sheep and other small animals. Some animals get frightened when they only smell a man. Some of themst and and look at a man for a short time before they run away.

  14. Reproductive handle of the herd of cattle of double purpose

    International Nuclear Information System (INIS)

    The influence of the environmental factors is analyzed, in the reproductive efficiency of herd cattle of double purpose. The reproductive behavior begins with the gestation of the heifers. Under the conditions of the Colombian tropic these they reach the weight required for the reproduction to an age but late that in the temperate areas. Once the first childbirth, the cow takes place it enters in exhaustion that makes that this animal is the but difficult to reproduce after the childbirth, that which demands special cares of handling and feeding. The interval among the childbirth to evaluate the reproductive efficiency. Environmental factors that influence significantly. The use of the practice simple of handling, health, selection and feeding produces significant increments in the fertility of the herd of cattle of double purpose. One practices of effective handling in the improvement of the reproductive behavior of the cows of double purpose it is the restricted nursing

  15. Identification of inflammatory processes in temporomandibular joint (TMJ) by 99mTc-HMPAO in animal model

    International Nuclear Information System (INIS)

    Temporomandibular joint (TMJ) is a synovial joint that represents the junction of mandible with skull. TMJ and mastication muscles are affected by temporomandibular disorders (TMDs). During the last two decades the advances in imaging diagnostic of TMJ have greatly contributed to the assessment of the TMJ disorders. Labelled leukocytes with technetium- 99m hexamethyl propylene amine oxime (99mTc-HMPAO) represent an efficient method that generates images based in physiological and/or biochemical changes related to inflammation. The aim of this study was to investigate the potential usefulness of technetium-99m labelled leukocytes scintigraphy in the diagnosis of TMJ inflammatory process applying a rabbit TMJ arthritis model. Arthritis was induced unilaterally with an intra-articular injection of ovalbumin in left ATM. On the contra-lateral side, the same dose of saline was injected. After five days, leukocytes were labeled with HMPAO and 99mTc-HMPAO TMJ scintigraphic images were made. After twelve days a computed tomography was realized. Scintigraphic images obtained five days after induction of TMJ inflammation showed the localization of inflammatory process. The results were expressed as cpm of activity found in left ATM and contra-lateral side. Significant differences of activity were found between inflamed articulation and contra-lateral side (P = 0,0073). In conclusion, the method of leukocytes labeled with 99mTc showed to be sensitive in detection of inflammatory disorders of TMJ and can be of great value in early diagnostic of these disorders. (author)

  16. Magnetic Resonance Imaging of Postoperative Fracture Healing Process without Metal Artifact: A Preliminary Report of a Novel Animal Model.

    Science.gov (United States)

    Jin, Zhe; Guan, Yuheng; Yu, Guibo; Sun, Yu

    2016-01-01

    Background. Early radiological diagnosis and continual monitoring are of ultimate importance for timely treatment of delayed union, nonunion, and infection after bone fracture surgery. Although magnetic resonance imaging (MRI) could provide superior detailed images compared with X-ray and computed tomography (CT) without ionizing radiation, metal implants used for fracture fixation lead to abundant artifacts on MRI and thus prohibit accurate interpretation. The authors develop a novel intramedullary fixation model of rat femoral fracture using polyetheretherketone (PEEK) threaded rods and investigate its feasibility for in vivo MRI monitoring of the fracture healing process without artifact. Methods. Femoral fractures of 3 adult male Sprague-Dawley rats were fixed with intramedullary PEEK threaded rods. X-ray and MRI examinations were performed at day 7 postoperatively. Radiological images were analyzed for the existence of artifact interruption and postoperative changes in bone and peripheral soft tissue. Results. Postoperative plain film revealed no loss of reduction. MRI images illustrated the whole length of femur and peripheral tissue without artifact interruption, and the cortical bone, implanted PEEK rod, and soft tissue were clearly illustrated. Conclusion. This preliminary study introduced a novel rat model for in vivo MRI monitoring of the fracture healing process without metal artifact, by using intramedullary fixation of femur with PEEK threaded rod. PMID:27123442

  17. Magnetic Resonance Imaging of Postoperative Fracture Healing Process without Metal Artifact: A Preliminary Report of a Novel Animal Model

    Directory of Open Access Journals (Sweden)

    Zhe Jin

    2016-01-01

    Full Text Available Background. Early radiological diagnosis and continual monitoring are of ultimate importance for timely treatment of delayed union, nonunion, and infection after bone fracture surgery. Although magnetic resonance imaging (MRI could provide superior detailed images compared with X-ray and computed tomography (CT without ionizing radiation, metal implants used for fracture fixation lead to abundant artifacts on MRI and thus prohibit accurate interpretation. The authors develop a novel intramedullary fixation model of rat femoral fracture using polyetheretherketone (PEEK threaded rods and investigate its feasibility for in vivo MRI monitoring of the fracture healing process without artifact. Methods. Femoral fractures of 3 adult male Sprague-Dawley rats were fixed with intramedullary PEEK threaded rods. X-ray and MRI examinations were performed at day 7 postoperatively. Radiological images were analyzed for the existence of artifact interruption and postoperative changes in bone and peripheral soft tissue. Results. Postoperative plain film revealed no loss of reduction. MRI images illustrated the whole length of femur and peripheral tissue without artifact interruption, and the cortical bone, implanted PEEK rod, and soft tissue were clearly illustrated. Conclusion. This preliminary study introduced a novel rat model for in vivo MRI monitoring of the fracture healing process without metal artifact, by using intramedullary fixation of femur with PEEK threaded rod.

  18. Epigenetics and assisted reproductive technologies.

    Science.gov (United States)

    Pinborg, Anja; Loft, Anne; Romundstad, Liv B; Wennerholm, Ulla-Britt; Söderström-Anttila, Viveca; Bergh, Christina; Aittomäki, Kristiina

    2016-01-01

    Epigenetic modification controls gene activity without changes in the DNA sequence. The genome undergoes several phases of epigenetic programming during gametogenesis and early embryo development, coinciding with assisted reproductive technologies (ART) treatments. Imprinting disorders have been associated with ART techniques, but disentangling the influence of the ART procedures per se from the effect of the reproductive disease of the parents is a challenge. Epidemiological human studies have shown altered birthweight profiles in ART compared with spontaneously conceived singletons. Conception with cryopreserved/thawed embryos results in a higher risk of large-for-gestational-age babies, which may be due to epigenetic modification. Further animal studies have shown altered gene expression profiles in offspring conceived by ART related to altered glucose metabolism. It is controversial whether human adolescents conceived by ART have altered lipid and glucose profiles and thereby a higher long-term risk of cardiovascular disease and diabetes. This commentary describes the basic concepts of epigenetics and gives a short overview of the existing literature on the association between imprinting disorders, epigenetic modification and ART. PMID:26458360

  19. QSAR Models for Reproductive Toxicity and Endocrine Disruption Activity

    OpenAIRE

    Marjan Vračko; Marjana Novič

    2010-01-01

    Reproductive toxicity is an important regulatory endpoint, which is required in registration procedures of chemicals used for different purposes (for example pesticides). The in vivo tests are expensive, time consuming and require large numbers of animals, which must be sacrificed. Therefore an effort is ongoing to develop alternative In vitro and in silico methods to evaluate reproductive toxicity. In this review we describe some modeling approaches. In the first example we describe the CAES...

  20. The role of the brain in female reproductive aging

    OpenAIRE

    Downs, Jodi L.; Wise, Phyllis M.

    2008-01-01

    In middle-aged women, follicular depletion is a critical factor mediating the menopausal transition; however, all levels of the hypothalamic-pituitary-gonadal (HPG) axis contribute to the age-related decline in reproductive function. To help elucidate the complex interactions between the ovary and brain during middle-age that lead to the onset of the menopause, we utilize animal models which share striking similarities in reproductive physiology. Our results show that during middle-age, prior...

  1. Reproduction and genetic diversity of the swamp buffalo

    OpenAIRE

    Yindee, M.

    2011-01-01

    The water buffalo is one of the most important domestic animals in Southeast Asia including Thailand. As the Thai swamp buffalo population declined during the last two decades, the swamp buffalo reproductive performance needs to be improved. Lack of knowledge on swamp buffalo reproduction, improper management and failure to use genetic superior males and females in breeding programs are the major factors to be considered. Artificial insemination was applied in Thailand but is inefficient due ...

  2. Nearby grandmother enhances calf survival and reproduction in Asian elephants

    OpenAIRE

    Mirkka Lahdenperä; Khyne U Mar; Virpi Lummaa

    2016-01-01

    Usually animals reproduce into old age, but a few species such as humans and killer whales can live decades after their last reproduction. The grandmother hypothesis proposes that such life-history evolved through older females switching to invest in their existing (grand)offspring, thereby increasing their inclusive fitness and selection for post-reproductive lifespan. However, positive grandmother effects are also found in non-menopausal taxa, but evidence of their associated fitness effect...

  3. Diet mediates the relationship between longevity and reproduction in mammals

    OpenAIRE

    Wilder, Shawn M.; Le Couteur, David G; Simpson, Stephen J.

    2012-01-01

    The disposable soma hypothesis posits a negative correlation between longevity and reproduction, presumably because these aspects of fitness compete for a limited pool of nutrients. However, diet, which varies widely among animals, could affect the availability of key nutrients required for both reproduction and longevity, especially protein. We used a comparative database of mammal life history data to test the hypothesis that carnivores experience less of a negative relationship between rep...

  4. The use of rabbits in male reproductive toxicology.

    OpenAIRE

    Morton, D.

    1988-01-01

    The rabbit is the smallest and least expensive laboratory animal in which serial semen samples can be obtained for morphologic, biochemical, and fertility evaluation. The female rabbit has a predictable reproductive cycle and can be artificially inseminated with a known amount of sperm during fertility testing. These advantages make the rabbit an extremely valuable model for studying the effects of chemicals or other stimuli on the male reproductive system. Quantitative evaluation of the test...

  5. The Role of Reproductive Hormones in Postpartum Depression

    OpenAIRE

    Schiller, Crystal Edler; Meltzer-Brody, Samantha; Rubinow, David R.

    2014-01-01

    Despite decades of research aimed at identifying the causes of postpartum depression (PPD), PPD remains common, and the causes are poorly understood. Many have attributed the onset of PPD to the rapid perinatal change in reproductive hormones. Although a number of human and non-human animal studies support the role of reproductive hormones in PPD, several studies have failed to detect an association between hormone concentrations and PPD. The purpose of this review is to examine the hypothesi...

  6. A category approach for reproductive effects of phthalates.

    OpenAIRE

    Fabjan, Evelin; Hulzebos, Etje; Mennes, W.; Piersma, Aldert H

    2006-01-01

    In regulatory toxicology, the experimental assessment of reproductive toxicity is one of the most costly endpoints to perform. Categorizing chemicals is an approach that can be used to reduce animal tests in risk assessments of chemicals, for example, via REACH (Registration, Evaluation, and Authorization of Chemicals). The category approach was tested for reproductive toxicity with a group of 10 ortho-phthalate esters, with different side chain lengths. Three ortho-phthalates were used for t...

  7. Reproductive data for groundfish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The ROCKFISH database houses data from rockfish species collected by the SWFSC FED along the California coast as part of a reproductive study originating in the...

  8. Assisted Reproductive Technology

    Science.gov (United States)

    Assisted reproductive technology (ART) is used to treat infertility. It includes fertility treatments that handle both a woman's egg ... back in the woman's body. In vitro fertilization (IVF) is the most common and effective type of ...

  9. Animal performance

    OpenAIRE

    Abaye, A. O. (Azenegashe Ozzie); Rotz, Jonathan Daniel; Scaglia Alonso, Guillermo, 1963-; Fike, John Herschel; Smith, Ray Lee, 1962-

    2009-01-01

    Any forage crop that stretches the grazing season by providing additional feed in early spring, mid-summer, and late fall will provide the livestock producer with lower feed costs and boost animal performance.

  10. Animation & Neurocinematics*

    DEFF Research Database (Denmark)

    Carpe Pérez, Inmaculada Concepción

    2016-01-01

    , indeed, can be considered a social/ emotional learning media, which goes beyond the limitations of live action movies. This is due to the diversity of techniques, and its visual plasticity that constructs the impossible. Animators are not real actors but more like the midwife who brings the anima...... machines that think”-(Damasio, A. Descartes error). Such feelings come from the interpretation of the emotions in our bodies. Emotions are our universal language, the motivation of living, the key to what makes a movie successful and truly an art piece that you will remember because moves you. Animation...... into aliveness, which requires knowing how emotions work. Ed Hooks as an expert in training animators and actors, always remarks: “emotions tend to lead to action”. In this paper we want to argue that by producing animated films, as we watch them, cause a stronger effect, not only in our brains, but also in our...

  11. Epigenetics and assisted reproductive technologies

    DEFF Research Database (Denmark)

    Pinborg, Anja; Loft, Anne; Romundstad, Liv Bente;

    2016-01-01

    Epigenetic modification controls gene activity without changes in the DNA sequence. The genome undergoes several phases of epigenetic programming during gametogenesis and early embryo development coinciding with assisted reproductive technologies (ART) treatments. Imprinting disorders have been...... with cryopreserved/thawed embryos results in a higher risk of large-for-gestational age babies, which may be due to epigenetic modification. Further animal studies have shown altered gene expression profiles in offspring conceived by ART related to altered glucose metabolism. It is controversial whether human...... adolescents conceived by ART have altered lipid and glucose profiles and thereby a higher long-term risk of cardiovascular disease and diabetes. This commentary describes the basic concepts of epigenetics and gives a short overview of the existing literature on the association between imprinting disorders...

  12. Groundwater animals

    OpenAIRE

    Maurice, Louise; Bloomfield, John; Robertson, Anne; Allen, Debbie

    2010-01-01

    Groundwater animals are adapted to live in environments with no light and limited nutrients, They can provide insights into fundamental questions of evolution, ecology and biodiversity. They also have an important role to play in informing the reconstruction of past changes in geomorphology and climate, and can be used for characterising aquifers. The BGS is undertaking a systematic survey of selected areas and lithologies in the UK where groundwater animals have not been inves...

  13. Selective Reproductive Technologies

    OpenAIRE

    Gammeltoft, Tine; WAHLBERG, Ayo

    2014-01-01

    From a historical perspective, selective reproduction is nothing new. Infanticide, abandonment, and selective neglect of children have a long history, and the widespread deployment of sterilization and forced abortion in the twentieth century has been well documented. Yet in recent decades selective reproduction has been placed under the aegis of science and expertise in novel ways. New laboratory and clinical techniques allow for the selective fertilization of gametes, implantation of embryo...

  14. Eating disorders and reproduction.

    Science.gov (United States)

    Morgan, J F

    1999-05-01

    Eating disorders are common and characteristically affect young women at what would otherwise be their peak of reproductive functioning. Anorexia nervosa and bulimia nervosa impinge on reproduction both behaviourally and physiologically, with effects on menstruation, ovarian function, fertility, sexuality and pregnancy. This review presents a summary of current knowledge and makes suggestions for future research, along with some clinical recommendations for the management of eating disorders in pregnancy. PMID:10755771

  15. Reproductive Liberty and Overpopulation

    OpenAIRE

    Carol A. Kates

    2004-01-01

    Despite substantial evidence pointing to a looming Malthusian catastrophe, governmental measures to reduce population have been opposed both by religious conservatives and by many liberals, especially liberal feminists. Liberal critics have claimed that 'utilitarian' population policies violate a 'fundamental right of reproductive liberty'. This essay argues that reproductive liberty should not be considered a fundamental human right, or certainly not an indefeasible right. It should, instead...

  16. Avian reproductive physiology

    Science.gov (United States)

    Gee, G.F.

    1995-01-01

    Knowledge of the many physiological factors associated with egg production , fertility, incubation, and brooding in nondomestic birds is limited. Science knows even less about reproduction in most of the 238 endangered or threatened birds. This discussion uses studies of nondomestic and, when necessary, domestic birds to describe physiological control of reproduction. Studies of the few nondomestic avian species show large variation in physiological control of reproduction. Aviculturists, in order to successfully propagate an endangered bird, must understand the bird's reproductive peculiarities. First, investigators can do studies with carefully chosen surrogate species, but eventually they need to confirm the results in the target endangered bird. Studies of reproduction in nondomestic birds increased in the last decade. Still, scientists need to do more comparative studies to understand the mechanisms that control reproduction in birds. New technologies are making it possible to study reproductive physiology of nondomestic species in less limiting ways. These technologies include telemetry to collect information without inducing stress on captives (Howey et al., 1987; Klugman, 1987), new tests for most of the humoral factors associated with reproduction, and the skill to collect small samples and manipulate birds without disrupting the physiological mechanisms (Bercovitz et al., 1985). Managers are using knowledge from these studies to improve propagation in zoological parks, private and public propagation facilities, and research institutions. Researchers need to study the control of ovulation, egg formation, and oviposition in the species of nondomestic birds that lay very few eggs in a season, hold eggs in the oviduct for longer intervals, or differ in other ways from the more thoroughly studied domestic birds. Other techniques that would enhance propagation for nondomestlc birds include tissue culture of cloned embryonic cells, cryopreservation of embryos

  17. The Climate Space Concept: Analysis of the Steady State Heat Energy Budget of Animals. Physical Processes in Terrestrial and Aquatic Ecosystems, Transport Processes.

    Science.gov (United States)

    Stevenson, R. D.

    These materials were designed to be used by life science students for instruction in the application of physical theory to ecosystem operation. Most modules contain computer programs which are built around a particular application of a physical process. Several modules in the thermodynamic series considered the application of the First Law to…

  18. Practical Applications of Sperm Selection Techniques as a Tool for Improving Reproductive Efficiency

    Directory of Open Access Journals (Sweden)

    J. M. Morrell

    2011-01-01

    Full Text Available Modern biotechnologies are used extensively in the animal breeding industry today. Therefore, it is essential that sperm handling procedures do not modulate the normal physiological mechanisms occurring in the female reproductive tract. In this paper, the different selection mechanisms occurring in vivo are described briefly, together with their relevance to artificial insemination, followed by a detailed description of the different selection processes used in reproductive biotechnologies. These selection methods included fractionated semen collection, cryopreservation, biomimetic sperm selection, selection based on hyaluronic acid binding, and last, but not least, sperm sex selection. Biomimetic sperm selection for AI or for cryopreservation could improve pregnancy rates and help to reverse the decline in fertility seen in several domestic species over the recent decades. Similarly, selection for hyaluronic acid binding sites may enable the most mature spermatozoa to be selected for IVF or ICSI.

  19. Asexual Reproduction in Holothurians

    Directory of Open Access Journals (Sweden)

    Igor Yu. Dolmatov

    2014-01-01

    Full Text Available Aspects of asexual reproduction in holothurians are discussed. Holothurians are significant as fishery and aquaculture items and have high commercial value. The last review on holothurian asexual reproduction was published 18 years ago and included only 8 species. An analysis of the available literature shows that asexual reproduction has now been confirmed in 16 holothurian species. Five additional species are also most likely capable of fission. The recent discovery of new fissiparous holothurian species indicates that this reproduction mode is more widespread in Holothuroidea than previously believed. New data about the history of the discovery of asexual reproduction in holothurians, features of fission, and regeneration of anterior and posterior fragments are described here. Asexual reproduction is obviously controlled by the integrated systems of the organism, primarily the nervous system. Special molecular mechanisms appear to determine the location where fission occurs along the anterior-posterior axis of the body. Alteration of the connective tissue strength of the body wall may play an important role during fission of holothurians. The basic mechanism of fission is the interaction of matrix metalloproteinases, their inhibitors, and enzymes forming cross-link complexes between fibrils of collagen. The population dynamics of fissiparous holothurians are discussed.

  20. The influence of radiation on reproduction of sheep

    International Nuclear Information System (INIS)

    Qualitative and quantitative histological changes in the sexual apparatus of slovak merino ewes were studies in the anoestrous period after irradiation (2.5 Gy) and hormonal stimulation. Estrus synchronization of the sheep has been carried out by application of 20 mg chlorosuperlutine in impregnated vaginal Ageline sponges. The sheep were hormone stimulated by application of 1500 IU of Serum gonadotrophin. The animals were killed approximately 120 h after the application of the hormone. Samples from the sexual apparatus were processed by the common histological methods for examination under a light microscope and for examination under a scanning electron microscope (SEM). Despite higher number of ovulations in irradiated and hormonally stimulated sheep, the examination of viability of irradiated oocytes showed absence of pregnancy in all 20 sheep after mating. This indicated that the dose of 2.5 Gy was not harmless to the reproductive system of sheep. (authors)

  1. Biological studies in animal models using [99mTc](CO)3 recombinant annexin V as diagnostic agent of apoptotic processes

    International Nuclear Information System (INIS)

    Introduction: There are many diseases associated with variations in the expression of apoptosis such as organ rejection after transplantation, myocardial ischemia or infarct and neurodegenerative diseases. For this reason, the early visualization of this process is relevant to set fast and effective therapeutic strategies. Methods: The precursor was prepared according to the procedure reported by R. Alberto, R. Schibli, P. Schubiger, U. Abram, and T. Kaden [Reactions with the technetium and rhenium carbonyl complexes (NEt4)[MX3(CO)3]. Synthesis and structure of Tc(CN-But)3(CO)3](NO3) and (Net4)[Tc2(μ-SCH2CH2OH)3(CO)3], Polyhedron 1996;15: 1079-89]. Recombinant annexin V was incubated with [99mTc](H2O)3(CO)3+ solution, previously neutralized with buffer. Biodistribution studies were performed in 8-week-old female Wistar rats. Animals were housed and treated in compliance with institutional guidelines related to animal experimentation. Work protocol was previously approved by the Animal Ethics Committee of the university. Two groups of rats were defined. One was used as control and the other group was previously injected with 150 mg/kg ip of cyclophosphamide to induce apoptosis. Results: The synthesis of carbonyl precursor achieved yields higher than 90%, and the radiolabeled protein was obtained with 92% of radiochemical purity and high stability in vitro. An important uptake in apoptotic tissues was confirmed by biodistributions, scintigraphic images and histological studies. Conclusions: Biodistribution studies revealed hepatobiliary elimination, high stability in vivo and important uptake in the reticuloendothelial system. In the pathologic model, higher uptake values correspond to the liver, spleen, lungs and femur. Histological studies confirmed the development of apoptosis at 8 and 24 h postinduction in the spleen and lymphocyte bulks in the peribronchial area. Scintigraphic images confirmed high uptake both the spleen and the lungs.

  2. Features and News: The Importance of Discoveries in Animal Science to Human Welfare

    Science.gov (United States)

    BioScience, 1972

    1972-01-01

    Five short notes describe the contributions to human welfare of animal research in reproductive physiology; ruminant nutrition; meat science research; genetics and animal breeding; and recycling food by-products. (AL)

  3. Synergies between assisted reproduction technologies and functional genomics.

    Science.gov (United States)

    Loi, Pasqualino; Toschi, Paola; Zacchini, Federica; Ptak, Grazyna; Scapolo, Pier A; Capra, Emanuele; Stella, Alessandra; Marsan, Paolo Ajmone; Williams, John L

    2016-01-01

    This review, is a synopsis of advanced reproductive technologies in farm animals, including the discussion of their limiting factors as revealed by the study of offspring derived from embryos produced in vitro and through cloning. These studies show that the problems of epigenetic mis-programming, which were reported in the initial stages of assisted reproduction, still persist. The importance of whole-genome analyses, including the methylome and transcriptome, in improving embryo biotechnologies in farm animals, are discussed. Genome editing approaches for the improvement of economically-relevant traits in farm animals are also described. Efficient farm animal embryo biotechnologies, including cloning and the most recent technologies such as genome editing, will effectively complement the latest strategies to accelerate genetic improvement of farm animals. PMID:27481215

  4. Animal production and health newsletter. No. 18

    International Nuclear Information System (INIS)

    This newsletter contains brief summaries of the final Research Co-ordination Meetings of Co-ordinated Research Programmes on ''Strengthening Animal Reproduction Research in Asia Through the Application of Immunoassay Techniques'' and ''Strengthening Animal Disease Diagnosis in Asia Through Application of Immunoassay Techniques'' and of the first Research Co-ordination Meeting on ''Development of Feed Supplementation Strategies for Milk-Producing Animals in Tropical and Subtropical Environments Through the Use of Nuclear and Related Techniques''. Developments at the IAEA's Animal Production Unit, Seibersdorf, are described

  5. Reducing hazards for animals from humans

    Directory of Open Access Journals (Sweden)

    Paul-Pierre Pastoret

    2012-06-01

    Full Text Available If animals may be a source of hazards for humans, the reverse is equally true. The main sources of hazards from humans to animals, are the impact of human introduction of transboundary animal diseases, climate change, globalisation, introduction of invasive species and reduction of biodiversity.There is also a trend toward reducing genetic diversity in domestic animals, such as cattle; there are presently around 700 different breeds of cattle many of which at the verge of extinction (less than 100 reproductive females. The impact of humans is also indirect through detrimental effects on the environment. It is therefore urgent to implement the new concept of “one health"....

  6. [Distribution of the different patterns of aging over the system of animal world].

    Science.gov (United States)

    Popov, I Iu

    2011-01-01

    Since the system of animal world reflects evolutionary trends, an analysis of distribution of patterns of aging over this system provides information on the causes of the formation of differences among them. In this paper the system of the main animal groups in form of a table is presented, and the distribution of patterns demonstrating minimum and maximum of aging is discussed. Meanwhile the colonial animals are considered as a "minimum of aging", the animals demonstrating drastic self-liquidation after reproduction are considered as a "maximum of aging" (the most well-known example is the pink salmon). It is shown, that as far as the degree of difference from the simplest ancestor increases in process of evolution, the increase of the manifestations of aging takes place. Slow aging of relatively simple organisms cannot be a direct source of measures to prevent aging of complex ones. PMID:21957572

  7. Identification of Proteins and Peptide Biomarkers for Detecting Banned Processed Animal Proteins (PAPs) in Meat and Bone Meal by Mass Spectrometry.

    Science.gov (United States)

    Marbaix, Hélène; Budinger, Dimitri; Dieu, Marc; Fumière, Olivier; Gillard, Nathalie; Delahaut, Philippe; Mauro, Sergio; Raes, Martine

    2016-03-23

    The outbreak of bovine spongiform encephalopathy (BSE) in the United Kingdom in 1986, with processed animal proteins (PAPs) as the main vector of the disease, has led to their prohibition in feed. The progressive release of the feed ban required the development of new analytical methods to determine the exact origin of PAPs from meat and bone meal. We set up a promising MS-based method to determine the species and the source (legal or not) present in PAPs: a TCA-acetone protein extraction followed by a cleanup step, an in-solution tryptic digestion of 5 h (with a 1:20 protein/trypsin ratio), and mass spectrometry analyses, first without any a priori, with a Q-TOF, followed by a targeted triple-quadrupole analysis. Using this procedure, we were able to overcome some of the major limitations of the official methods to analyze PAPs, detecting and identifying prohibited animal products in feedstuffs by the monitoring of peptides specific for cows, pigs, and sheep in PAPs. PMID:26943838

  8. The reproductive cycle of the oyster Crassostrea gasar.

    Science.gov (United States)

    Gomes, C H A M; Silva, F C; Lopes, G R; Melo, C M R

    2014-11-01

    The purpose of this study was to analyze the reproductive cycle of the oyster Crassostrea gasar (= C. brasiliana) in the field and the laboratory. The reproductive cycle of the animals was evaluated in the field at Sambaqui Beach, Florianópolis, SC (27° 29'18″ S and 48° 32'12″ W) from May 2008 through November 2009. In July, the animals were in the resting stage. The early growth stage began in August and was followed by the late growth stage in October. In November and December, the oysters began to enter the mature stage. Females in spawning condition were predominant during these months. The stages of the reproductive cycle were positively associated with temperature (r=0.77, Preproductive development of Crassostrea gasar. The condition index (CI) of the animals was also associated with the seawater temperature. The highest values of the condition index were observed during the months when the temperature of the seawater was gradually increasing. A laboratory experiment was performed to test the effect of salinity on the reproductive cycle of the oysters. The experiment was conducted in standardized tanks. The animals were conditioned using two salinities (24‰ and 34‰). The salinity regime influenced the development of the gonadal tissue of the oysters. A salinity of 24‰ produced greater reproductive development. PMID:25627610

  9. Introduction to Reproduction: Online Education for the Millennial Learner.

    Science.gov (United States)

    Castle, Megan; Kick, Laura; Haseley, Heather; Wallach, Harlan; Woodruff, Teresa K

    2016-07-01

    Despite staggering rates of sexually transmitted infections and unplanned pregnancies, reproductive health education is not yet standardized across secondary or postsecondary curricula. The Women's Health Research Institute and Northwestern University Information Technology created Introduction to Reproduction, a massive open online course to encourage global students to learn the biological foundations of reproductive health. This digital education experience appeals to the Millennial learner and offers unique opportunities to explore topics in reproductive biology via lectures, animations, and three-dimensional anatomical illustrations. Data were collected anonymously from de-identified learners who elected to self-report on their experiences while completing the course as well as through Coursera datasets. Northwestern University's Institutional Review Board classified this research project as an exempt status due to the de-identified nature of the collected data. Participants from 47 countries report on reproductive health content knowledge, past reproductive health education, and level of engagement with the topic. These data indicate that the Introduction to Reproduction course has a meaningful impact on its participants and presents the information in a concise and accessible format. Distribution of this course to a wider audience is the goal for the program and important to the field of reproductive health. PMID:27335073

  10. Genetic improvement of dairy cow reproductive performance.

    Science.gov (United States)

    Berglund, B

    2008-07-01

    The welfare of cow along with profitability in production are important issues in sustainable animal breeding programmes. Along with an intense/intensive selection for increased milk yield, reproductive performance has declined in many countries, in part due to an unfavourable genetic relationship. The largely unchanged genetic trend in female fertility and calving traits for Scandinavian Red breeds shows that it is possible to avoid deterioration in these traits if they are properly considered in the breeding programme. Today's breeding is international with a global selection and extensive use of the best bulls. The Nordic countries have traditionally recorded and performed genetic evaluation for a broad range of functional traits including reproduction. In recent years many other countries have also implemented genetic evaluation for these traits. Thus, the relative emphasis of dairy cattle breeding objectives has gradually shifted from production to functional traits such as reproduction. Improved ways of recording traits, e.g. physiological measures, early indicator traits, assisted reproductive techniques and increased knowledge of genes and their regulation may improve the genetic selection strategies and have large impact on present and future genetic evaluation programmes. Extensive data bases with phenotypic recordings of traits for individuals and their pedigree are a prerequisite. Quantitative trait loci have been associated to the reproductive complex. Most important traits, including reproduction traits are regulated by a multitude of genes and environmental factors in a complex relationship, however. Genomic selection might therefore be important in future breeding programmes. Information on single nucleotide polymorphism has already been introduced in the selection programmes of some countries. PMID:18638109

  11. Assessment of auditory sensory processing in a neurodevelopmental animal model of schizophrenia-Gating of auditory-evoked potentials and prepulse inhibition

    DEFF Research Database (Denmark)

    Broberg, Brian Villumsen; Oranje, Bob; Yding, Birte;

    2010-01-01

    The use of translational approaches to validate animal models is needed for the development of treatments that can effectively alleviate cognitive impairments associated with schizophrenia, which are unsuccessfully treated by the current available therapies. Deficits in pre-attentive stages of...... sensory information processing seen in schizophrenia patients, can be assessed by highly homologues methods in both humans and rodents, evident by the prepulse inhibition (PPI) of the auditory startle response and the P50 (termed P1 here) suppression paradigms. Treatment with the NMDA receptor antagonist...... PCP on postnatal days 7, 9, and 11 reliably induce cognitive impairments resembling those presented by schizophrenia patients. Here we evaluate the potential of early postnatal PCP (20mg/kg) treatment in Lister Hooded rats to induce post-pubertal deficits in PPI and changes, such as reduced gating, in...

  12. Reproduction-related genes in the pearl oyster genome.

    Science.gov (United States)

    Matsumoto, Toshie; Masaoka, Tetsuji; Fujiwara, Atsushi; Nakamura, Yoji; Satoh, Nori; Awaji, Masahiko

    2013-10-01

    Molluscan reproduction has been a target of biological research because of the various reproductive strategies that have evolved in this phylum. It has also been studied for the development of fisheries technologies, particularly aquaculture. Although fundamental processes of reproduction in other phyla, such as vertebrates and arthropods, have been well studied, information on the molecular mechanisms of molluscan reproduction remains limited. The recently released draft genome of the pearl oyster Pinctada fucata provides a novel and powerful platform for obtaining structural information on the genes and proteins involved in bivalve reproduction. In the present study, we analyzed the pearl oyster draft genome to screen reproduction-related genes. Analysis was mainly conducted for genes reported from other molluscs for encoding orthologs of reproduction-related proteins in other phyla. The gene search in the P. fucata gene models (version 1.1) and genome assembly (version 1.0) were performed using Genome Browser and BLAST software. The obtained gene models were then BLASTP searched against a public database to confirm the best-hit sequences. As a result, more than 40 gene models were identified with high accuracy to encode reproduction-related genes reported for P. fucata and other molluscs. These include vasa, nanos, doublesex- and mab-3-related transcription factor, 5-hydroxytryptamine (5-HT) receptors, vitellogenin, estrogen receptor, and others. The set of reproduction-related genes of P. fucata identified in the present study constitute a new tool for research on bivalve reproduction at the molecular level. PMID:24125647

  13. Biotecnologia animal

    OpenAIRE

    Luiz Lehmann Coutinho; Millor Fernandes do Rosário; Erika Cristina Jorge

    2010-01-01

    A biotecnologia animal tem fornecido novas ferramentas para os programas de melhoramento e, dessa forma, contribuído para melhorar a eficiência da produção dos produtos de origem animal. No entanto, os avanços têm sido mais lentos do que antecipados, especialmente em razão da dificuldade na identificação dos genes responsáveis pelas características fenotípicas de interesse zootécnico. Três estratégias principais têm sido utilizadas para identificar esses genes - mapeamento de QTL, genes candi...

  14. A Taxonomy of Technical Animation

    Directory of Open Access Journals (Sweden)

    D. Vaněček

    2011-01-01

    Full Text Available The age in which we are living nowadays is characterized by rapid innovation in the development of information and communication technologies (ICT. This innovation has a significant influence on the education process. This article deals with computer animation in technical education. Our aim is to show the taxonomy of education animation. The paper includes practical examples of animation.

  15. Experimental Embryology of Sexual and Asexual Reproduction in Mammals

    Institute of Scientific and Technical Information of China (English)

    Dayuan Chen

    2006-01-01

    This research was carried out in the area of experimental embryology, which covers from animal fertilization to cloning. Two achievements in the field of reproductive biology have created major influence in the past 50 years. One is the discovery of sperm capacitation and the establishment of in vitro fertilization technology, and the other is the birth of somatic cell nuclear transfer animals. Although researches in reproductive biology have developed very quickly and a lot of literatures have been published, many basic theoretical questions are still remained illusive. This paper gives a brief description of our researches during the past decade.

  16. Animation-based Sketching

    DEFF Research Database (Denmark)

    Vistisen, Peter

    experiments has been carried out, applying animation-based sketching in various contexts and at varying points in the design process. In the studies, I evaluate the viability of the approach, the practical integration into the design process, and map how consensus between stakeholders in design can be...

  17. Estimation of genetic parameters for reproductive traits in alpacas.

    Science.gov (United States)

    Cruz, A; Cervantes, I; Burgos, A; Morante, R; Gutiérrez, J P

    2015-12-01

    One of the main deficiencies affecting animal breeding programs in Peruvian alpacas is the low reproductive performance leading to low number of animals available to select from, decreasing strongly the selection intensity. Some reproductive traits could be improved by artificial selection, but very few information about genetic parameters exists for these traits in this specie. The aim of this study was to estimate genetic parameters for six reproductive traits in alpacas both in Suri (SU) and Huacaya (HU) ecotypes, as well as their genetic relationship with fiber and morphological traits. Dataset belonging to Pacomarca experimental farm collected between 2000 and 2014 was used. Number of records for age at first service (AFS), age at first calving (AFC), copulation time (CT), pregnancy diagnosis (PD), gestation length (GL), and calving interval (CI) were, respectively, 1704, 854, 19,770, 5874, 4290 and 934. Pedigree consisted of 7742 animals. Regarding reproductive traits, model of analysis included additive and residual random effects for all traits, and also permanent environmental effect for CT, PD, GL and CI traits, with color and year of recording as fixed effects for all the reproductive traits and also age at mating and sex of calf for GL trait. Estimated heritabilities, respectively for HU and SU were 0.19 and 0.09 for AFS, 0.45 and 0.59 for AFC, 0.04 and 0.05 for CT, 0.07 and 0.05 for PD, 0.12 and 0.20 for GL, and 0.14 and 0.09 for CI. Genetic correlations between them ranged from -0.96 to 0.70. No important genetic correlations were found between reproductive traits and fiber or morphological traits in HU. However, some moderate favorable genetic correlations were found between reproductive and either fiber and morphological traits in SU. According to estimated genetic correlations, some reproductive traits might be included as additional selection criteria in HU. PMID:26490188

  18. Animal models of contraception: utility and limitations

    OpenAIRE

    Liechty ER; Bergin IL; Bell JD

    2015-01-01

    Emma R Liechty,1 Ingrid L Bergin,1 Jason D Bell2 1Unit for Laboratory Animal Medicine, 2Program on Women's Health Care Effectiveness Research, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA Abstract: Appropriate animal modeling is vital for the successful development of novel contraceptive devices. Advances in reproductive biology have identified novel pathways for contraceptive intervention. Here we review species-specific anatomic and physiologic co...

  19. Animal models of contraception: utility and limitations

    OpenAIRE

    Bell, Jason

    2015-01-01

    Emma R Liechty,1 Ingrid L Bergin,1 Jason D Bell2 1Unit for Laboratory Animal Medicine, 2Program on Women's Health Care Effectiveness Research, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA Abstract: Appropriate animal modeling is vital for the successful development of novel contraceptive devices. Advances in reproductive biology have identified novel pathways for contraceptive intervention. Here we review species-specific anatomic and physiologi...

  20. Facing the Beast Apart Together: Fear in Boys and Girls after Processing Information about Novel Animals Individually or in a Duo

    Science.gov (United States)

    Muris, Peter; Rijkee, Sanne

    2011-01-01

    In this experimental study, we made an attempt to examine gender-related peer influences on childhood fear. Nine- to 12-year-old boys and girls were provided with ambiguous and positive information about novel animals and then asked to provide a subjective fear rating of the animals under two conditions: fear of one animal was assessed…

  1. Animal house

    OpenAIRE

    Turka, Laurence A.

    2008-01-01

    While the JCI was originally conceived as a journal that would integrate various scientific approaches to the examination of human physiology and pathophysiology, we now find many of its pages filled with animal models of human disease. Is this a good thing?

  2. Transgenic Animals.

    Science.gov (United States)

    Jaenisch, Rudolf

    1988-01-01

    Describes three methods and their advantages and disadvantages for introducing genes into animals. Discusses the predictability and tissue-specificity of the injected genes. Outlines the applications of transgenic technology for studying gene expression, the early stages of mammalian development, mutations, and the molecular nature of chromosomes.…

  3. Dinosaur Reproduction and Parenting

    Science.gov (United States)

    Horner, John R.

    Non-avian dinosaur reproductive and parenting behaviors were mostly similar to those of extant archosaurs. Non-avian dinosaurs were probably sexually dimorphic and some may have engaged in hierarchical rituals. Non-avian coelurosaurs (e.g. Troodontidae, Oviraptorosauria) had two active oviducts, each of which produced single eggs on a daily or greater time scale. The eggs of non-coelurosaurian dinosaurs (e.g. Ornithischia, Sauropoda) were incubated in soils, whereas the eggs of non-avian coelurosaurs (e.g. Troodon, Oviraptor) were incubated with a combination of soil and direct parental contact. Parental attention to the young was variable, ranging from protection from predators to possible parental feeding of nest-bound hatchlings. Semi-altricial hadrosaur hatchlings exited their respective nests near the time of their first linear doubling. Some reproductive behaviors, once thought exclusive to Aves, arose first in non-avian dinosaurs. The success of the Dinosauria may be related to reproductive strategies.

  4. Introduction: Communicating Reproduction.

    Science.gov (United States)

    Hopwood, Nick; Jones, Peter Murray; Kassell, Lauren; Secord, Jim

    2015-01-01

    Communication should be central to histories of reproduction, because it has structured how people do and do not reproduce. Yet communication has been so pervasive, and so various, that it is often taken for granted and the historical specificities overlooked. Making communication a frame for histories of reproduction can draw a fragmented field together, including by putting the promotion of esoteric ideas on a par with other practical activities. Paying communication close attention can revitalize the history of reproduction over the long term by highlighting continuities as well as the complex connections between new technologies and new approaches. Themes such as the power of storytelling, the claiming and challenging of expertise, and relations between knowledge and ignorance, secrecy and propriety also invite further study. PMID:26521666

  5. Adult neurogenesis and reproductive functions in mammals.

    Science.gov (United States)

    Migaud, Martine; Butruille, Lucile; Duittoz, Anne; Pillon, Delphine; Batailler, Martine

    2016-07-01

    During adulthood, the mammalian brain retains the capacity to generate new cells and new neurons in particular. It is now well established that the birth of these new neurons occurs in well-described sites: the hippocampus and the subventricular zone of the lateral ventricle, as well as in other brain regions including the hypothalamus. In this review, we describe the canonical neurogenic niches and illustrate the functional relevance of adult-born neurons of each neurogenic niche in the reproductive physiology. More specifically, we highlight the effect of reproductive social stimuli on the neurogenic processes and conversely, the contributions of adult-born neurons to the reproductive physiology and behavior. We next review the recent discovery of a novel neurogenic niche located in the hypothalamus and the median eminence and the compelling evidence of the link existing between the new-born hypothalamic neurons and the regulation of metabolism. In addition, new perspectives on the possible involvement of hypothalamic neurogenesis in the control of photoperiodic reproductive physiology in seasonal mammals are discussed. Altogether, the studies highlighted in this review demonstrate the potential role of neurogenesis in reproductive function and emphasize the importance of increasing our knowledge on the regulation processes and the physiological relevance of these adult-born neurons. This constitutes a necessary step toward a potential manipulation of these plasticity mechanisms. PMID:27177964

  6. Animal Health in Albania

    International Nuclear Information System (INIS)

    The animal health service policy in Albania represents an integral component of overall governmental, social and economic policy in the field of agricultural and rural development, public health, food processing and import/export of animal products. In order to obtain the necessary political, economic and public support, the animal health service attempts to contribute effectively to the overall development of the country which aims at improving the standards of living of its inhabitants. Practical means of contributing to national development include reducing food loses due to animal morbidity and mortality, increasing the productivity of the livestock population, protecting human health against zoonotic diseases and ensuring humane treatment of animals. An animal health strategy contributes to the creation of conditions necessary for uninterrupted animal disease surveillance and control in the country. The main animal health problem in Albania is brucellosis in ruminants, caused by B. melitensis. This infection currently affects the entire country, reaching a prevalence of 10% in several districts. The latest and most severe outbreaks of classical swine fever were identified on 1996 when 5 515 animals were infected and 3 683 animals died. The circulation of bluetongue virus (BTV) was detected for the first time in Albania in 2002 with a seroprevalence of 15%. The evidence of BTV circulation in Albania and the absence of the main vector C. imicola suggest that other Culicoides species could be implicated in virus transmission. H5N1 avian influenza in Albania was confirmed in March 2006 in backyard flocks in the villages of Cuke and Peze-Helmes. In both villages there were no human cases. Rabies was of concern in Albania from 1928 until 1976. The disease re-emerged in March 2001 in the village of Morine in Kukes district affecting a domestic dog and three persons were bitten. Other cases have been reported in northern Albania. (author)

  7. Animal production and health newsletter. No. 3

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  8. Animal production and health newsletter. No. 11

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  9. Animal production and health newsletter. No. 2

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  10. Animal production and health newsletter. No. 1

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  11. Animal production and health newsletter. No. 10

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  12. Animal production and health newsletter. No. 12

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  13. Animal production and health newsletter. No. 7

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  14. Animal production and health newsletter. No. 8

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  15. Animal production and health newsletter. No. 5

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  16. Animal production and health newsletter. No. 4

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  17. Animal production and health newsletter. No. 6

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  18. Animal production and health newsletter. No. 9

    International Nuclear Information System (INIS)

    This Newsletter announces research coordination meetings, status of existing research coordinated research programmes on the use of isotope application in animal reproduction, nutrition and disease diagnostics. Training courses as well as new coordinated research programmes in the pipeline are also highlighted

  19. Reproductive rights under attack.

    Science.gov (United States)

    Mcdonald, K

    1995-01-01

    Women's groups, politicians, nongovernmental organizations, funding groups, and donor countries must all be lobbied with the message that sexual and reproductive health issues are inextricably linked to women in development, education, and future economic strength of nations worldwide. In the Beijing Nongovernmental Organization (NGO) Forum the draft Plan of Action had 35% of its language bracketed and subject to negotiation in Beijing. The previous International Conference on Population and Development (ICPD) in Cairo had only 15% of its language bracketed. Much of the language bracketed for Beijing had already been fully agreed upon before the Cairo conference. The bracketed language was in the health and human rights sections, and most of the language pertained to sexual and reproductive health. The increase in controversy is due to an opposition better organized in Beijing than it had been in Cairo, due to the opposition's failure to recognize the implications of the Cairo declarations on women, men, and children, and due to the opposition's general intolerance of sexual and reproductive issues. The major factor, however, was the linking of women's rights with sexual and reproductive health issues. Family planners joined with women's rights groups, which had always promoted women's control over their bodies as the cornerstone of equality. This connection was interpreted as a threat to the social order by conservative societies. NGO participants included 1400 people representing 170 countries. The NGO anti-abortion contingent was well-funded, well-organized, and large. Lobbying was conducted in an effort to convince people to oppose any language pertaining to gender, sexual and reproductive health, and adolescent rights. Anti-abortion lobbyists also rifled through documents of pro-choice participants. In Canada and the United States anti-abortion groups are lobbying hard to overturn the Cairo Plan of Action and to expand their efforts internationally among

  20. Conservation physiology of animal migration.

    Science.gov (United States)

    Lennox, Robert J; Chapman, Jacqueline M; Souliere, Christopher M; Tudorache, Christian; Wikelski, Martin; Metcalfe, Julian D; Cooke, Steven J

    2016-01-01

    Migration is a widespread phenomenon among many taxa. This complex behaviour enables animals to exploit many temporally productive and spatially discrete habitats to accrue various fitness benefits (e.g. growth, reproduction, predator avoidance). Human activities and global environmental change represent potential threats to migrating animals (from individuals to species), and research is underway to understand mechanisms that control migration and how migration responds to modern challenges. Focusing on behavioural and physiological aspects of migration can help to provide better understanding, management and conservation of migratory populations. Here, we highlight different physiological, behavioural and biomechanical aspects of animal migration that will help us to understand how migratory animals interact with current and future anthropogenic threats. We are in the early stages of a changing planet, and our understanding of how physiology is linked to the persistence of migratory animals is still developing; therefore, we regard the following questions as being central to the conservation physiology of animal migrations. Will climate change influence the energetic costs of migration? Will shifting temperatures change the annual clocks of migrating animals? Will anthropogenic influences have an effect on orientation during migration? Will increased anthropogenic alteration of migration stopover sites/migration corridors affect the stress physiology of migrating animals? Can physiological knowledge be used to identify strategies for facilitating the movement of animals? Our synthesis reveals that given the inherent challenges of migration, additional stressors derived from altered environments (e.g. climate change, physical habitat alteration, light pollution) or interaction with human infrastructure (e.g. wind or hydrokinetic turbines, dams) or activities (e.g. fisheries) could lead to long-term changes to migratory phenotypes. However, uncertainty remains

  1. RLMS Micro-File: Current State of Catalog Card Reproduction.

    Science.gov (United States)

    Nitecki, Joseph Z., Comp.

    Intended as a working tool for the administrators of library reprographic processes, this compilation includes 22 papers dealing with the technology of card reproduction for library catalogs. Among the reproduction devices discussed are the Copy Cat camera, the Cataloger's Camera, the Olivetti Enlarging Copier, and the IBM Magnetic Tape Selectric…

  2. Weighing the options for limiting surplus animals.

    Science.gov (United States)

    Asa, Cheryl

    2016-05-01

    The unsustainability of many animal programs managed by zoos and aquariums has brought renewed attention to unresolved questions about various management strategies. Solving the "sustainability crisis" for many species will require housing more adults and producing more offspring than there are existing spaces in accredited zoos and aquariums. Careful reproductive management is central to addressing this challenge, but opinions differ about which management strategies are best for an individual, for a species, for an institution, or for a country or region. The primary options for limiting the number of animals that would be surplus to the population are to prevent reproduction or to euthanize. However, there is much misunderstanding about methods for controlling reproduction, in particular about contraceptives and species differences in their effects. Careful weighing of all the options is called for. Lifetime Reproductive Planning may help increase breeding success through careful reproductive management but cannot eliminate production of surplus animals. Limiting reproduction does not address the problem of animals already in the population. Despite best efforts and planning, consistently hitting target numbers for a population may never be achieved. Increasing capacity provides a temporary patch when targets are exceeded, but is not a long-term solution, since each generation potentially produces even more individuals needing even more space. Welfare considerations should be included in discussions of management euthanasia and its alternatives. Such discussions will be most productive if based on full awareness of the advantages and disadvantages of all the options. Zoo Biol. 35:183-186, 2016. © 2016 Wiley Periodicals, Inc. PMID:27187931

  3. Zebrafish: A Versatile Animal Model for Fertility Research

    Science.gov (United States)

    Hoo, Jing Ying; Kumari, Yatinesh; Shaikh, Mohd Farooq; Hue, Seow Mun

    2016-01-01

    The utilization of zebrafish in biomedical research is very common in the research world nowadays. Today, it has emerged as a favored vertebrate organism for the research in science of reproduction. There is a significant growth in amount numbers of scientific literature pertaining to research discoveries in reproductive sciences in zebrafish. It has implied the importance of zebrafish in this particular field of research. In essence, the current available literature has covered from the very specific brain region or neurons of zebrafish, which are responsible for reproductive regulation, until the gonadal level of the animal. The discoveries and findings have proven that this small animal is sharing a very close/similar reproductive system with mammals. More interestingly, the behavioral characteristics and along with the establishment of animal courtship behavior categorization in zebrafish have laid an even stronger foundation and firmer reason on the suitability of zebrafish utilization in research of reproductive sciences. In view of the immense importance of this small animal for the development of reproductive sciences, this review aimed at compiling and describing the proximate close similarity of reproductive regulation on zebrafish and human along with factors contributing to the infertility, showing its versatility and its potential usage for fertility research.

  4. Ethics and assisted reproduction.

    Science.gov (United States)

    Fasouliotis, S J; Schenker, J G

    2000-06-01

    In vitro fertilization and assisted reproductive technology have made great progress during the last 20 years. Genetic material donation, human embryo cryopreservation, selective embryo reduction, preimplantation genetic diagnosis and surrogacy are currently practiced in many countries. On the other hand, embryo research is practiced only in a small number of nations, whereas human cloning has thus far been universally condemned. The rapid evolution and progress of all these techniques of assisted reproduction has revealed certain ethical issues that have to be addressed. PMID:10825637

  5. Reproductive Technology and Surrogacy

    OpenAIRE

    Ásgeirsson, Hrafn; Nordal, Salvör

    2015-01-01

    During the past few years, reproductive technology and surrogacy have emerged in a number of European countries as issues of debate. There has been a steady increase in the use of reproductive technology in the Nordic countries, as well as an increase in the use of cross-border medical treatment in order to achieve pregnancy. At the same time, a number of ethical issues have been raised concerning the rights of the participants, including the children. In the fall of 2013, the Nordic Committe...

  6. Biotecnologia animal

    Directory of Open Access Journals (Sweden)

    Luiz Lehmann Coutinho

    2010-01-01

    Full Text Available A biotecnologia animal tem fornecido novas ferramentas para os programas de melhoramento e, dessa forma, contribuído para melhorar a eficiência da produção dos produtos de origem animal. No entanto, os avanços têm sido mais lentos do que antecipados, especialmente em razão da dificuldade na identificação dos genes responsáveis pelas características fenotípicas de interesse zootécnico. Três estratégias principais têm sido utilizadas para identificar esses genes - mapeamento de QTL, genes candidatos e sequenciamento de DNA e mRNA - e cada uma tem suas vantagens e limitações. O mapeamento de QTL permite determinar as regiões genômicas que contêm genes, mas o intervalo de confiança do QTL pode ser grande e conter muitos genes. A estratégia de genes candidatos é limitada por causa do conhecimento ainda restrito das funções de todos os genes. Os sequenciamentos de genomas e de sequências expressas podem auxiliar na identificação da posição de genes e de vias metabólicas associadas à característica de interesse. A integração dessas estratégias por meio do desenvolvimento de programas de bioinformática permitirá a identificação de novos genes de interesse zootécnico. Assim, os programas de melhoramento genético se beneficiarão pela inclusão da informação obtida diretamente do DNA na avaliação do mérito genético dos plantéis disponíveis.Animal biotechnology is providing new tools for animal breeding and genetics and thus contributing to advances in production efficiency and quality of animal products. However, the progress is slower than anticipated, mainly because of the difficulty involved in identifying genes that control phenotypic characteristics of importance to the animal industry. Three main strategies: QTL mapping, candidate genes and DNA and mRNA sequencing have been used to identify genes of economic interest to animal breeding and each has advantages and disadvantages. QTL mapping allows

  7. Using a Delphi consensus process to develop an acupuncture treatment protocol by consensus for women undergoing Assisted Reproductive Technology (ART treatment

    Directory of Open Access Journals (Sweden)

    Smith Caroline A

    2012-07-01

    Full Text Available Abstract Background Assisted reproductive technologies (ART are increasingly utilised for resolving difficulties conceiving. These technologies are expensive to both the public purse and the individual consumers. Acupuncture is widely used as an adjunct to ART with indications that it may assist reducing the time to conception and increasing live birth rates. Heterogeneity is high between treatment protocols. The aim of this study was to examine what fertility acupuncturists consider key components of best practice acupuncture during an ART cycle, and to establish an acupuncture protocol by consensus. Methods Fifteen international acupuncturists with extensive experience treating women during ART interventions participated in 3 rounds of Delphi questionnaires. The first round focused on identifying the parameters of acupuncture treatment as adjunct to ART, the second round evaluated statements derived from the earlier round, and the third evaluated specific parameters for a proposed trial protocol. Consensus was defined as greater than 80% agreement. Results Significant agreement was achieved on the parameters of best practice acupuncture, including an acupuncture protocol suitable for future research. Study participants confirmed the importance of needling aspects relating to the dose of acupuncture, the therapeutic relationship, tailoring treatment to the individual, and the role of co-interventions. From two rounds of the Delphi a consensus was achieved on seven treatment parameters for the design of the acupuncture treatment to be used in a clinical trial of acupuncture as an adjunct to ART. The treatment protocol includes the use of the traditional Chinese medicine acupuncture, use of manual acupuncture, a first treatment administered between day 6–8 of the stimulated ART cycle which is individualised to the participant, two treatments will be administered on the day of embryo transfer, and will include points SP8, SP10, LR3, ST29, CV4

  8. Does it Pay to Delay? Flesh Flies Show Adaptive Plasticity in Reproductive Timing

    OpenAIRE

    Wessels, Frank J.; Kristal, Ross; Netter, Fleta; Hatle, John D.; Hahn, Daniel A.

    2010-01-01

    Life-history plasticity is widespread among organisms. However, an important question is whether this plasticity is adaptive, enhancing the organism’s fitness. Most models for plasticity in life-history timing predict that once they have reached the minimal nutritional threshold animals under poor conditions will accelerate timing to development or reproduction. Adaptive delays in reproductive timing are not common, especially in short-lived species. Examples of adaptive reproductive delays e...

  9. Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference

    OpenAIRE

    Costa, Raphael B.; Camargo, Gregório MF; Diaz, Iara DPS; Irano, Natalia; Dias, Marina M.; Carvalheiro, Roberto; Boligon, Arione A.; Baldi, Fernando; Henrique N. de Oliveira; Tonhati, Humberto; Albuquerque, Lucia G.

    2015-01-01

    Background An important goal of Zebu breeding programs is to improve reproductive performance. A major problem faced with the genetic improvement of reproductive traits is that recording the time for an animal to reach sexual maturity is costly. Another issue is that accurate estimates of breeding values are obtained only a long time after the young bulls have gone through selection. An alternative to overcome these problems is to use traits that are indicators of the reproductive efficiency ...

  10. Modelling the effects of environmental and individual variability when measuring the costs of first reproduction

    OpenAIRE

    Barbraud, C.; Weimerskirch, H

    2004-01-01

    How do animals balance their investment in young against their own chances to survive and reproduce in the future? This life–history trade–off, referred to as the cost of reproduction (Williams, 1966), holds a central place in life–history theory (Roff, 1992; Stearns, 1992; McNamara & Houston, 1996). Because individuals can only acquire a limited amount of energy, reproduction and survival as well as current and future reproduction are considered as functions competing for the same resources....

  11. Oxidative stress in relation to reproduction, contaminants, gender and age in a long-lived seabird

    OpenAIRE

    Costantini, David; Meillère, Alizée; Carravieri, Alice; Lecomte, Vincent; Sorci, Gabriele; Faivre, Bruno; Weimerskirch, Henri; Bustamante, Paco; Labadie, Pierre; Budzinski, Hélène; Chastel, Olivier

    2014-01-01

    Reproduction is a demanding activity for animals, since they must produce, and in some cases protect and provision, their young. It is often overlooked that demands of reproduction may also be exacerbated by exposure to contaminants. In this study, we make use of an exceptional long-term dataset to perform a cross-sectional study on the long-lived wandering albatross (Diomedea exulans) in order to test the effects of reproduction, persistent organic pollutants [POPs: pesticides and polychlori...

  12. Bisphenol A and Reproductive Health: Update of Experimental and Human Evidence, 2007–2013

    OpenAIRE

    Peretz, Jackye; Vrooman, Lisa; Ricke, William A.; Hunt, Patricia A.; Ehrlich, Shelley; Hauser, Russ; Padmanabhan, Vasantha; Taylor, Hugh S.; Swan, Shanna H; VandeVoort, Catherine A; Flaws, Jodi A

    2014-01-01

    Background: In 2007, an expert panel reviewed associations between bisphenol A (BPA) exposure and reproductive health outcomes. Since then, new studies have been conducted on the impact of BPA on reproduction. Objective: In this review, we summarize data obtained since 2007, focusing on a) findings from human and animal studies, b) the effects of BPA on a variety of reproductive end points, and c) mechanisms of BPA action. Methods: We reviewed the literature published from 2007 to 2013 using ...

  13. Biological studies in animal models using [{sup 99m}Tc](CO){sub 3} recombinant annexin V as diagnostic agent of apoptotic processes

    Energy Technology Data Exchange (ETDEWEB)

    Teran, Mariella Adriana, E-mail: mteran@fq.edu.u [Catedra de Radioquimica, Departamento Estrella Campos, Facultad de Quimica, Universidad de la Republica, P.O. 11800, Montevideo (Uruguay); Martinez, Elena; Reyes, Ana L.; Paolino, Andrea [Catedra de Radioquimica, Departamento Estrella Campos, Facultad de Quimica, Universidad de la Republica, P.O. 11800, Montevideo (Uruguay); Vital, Marcelo; Esperon, Patricia [Catedra de Biologia Molecular, Departamento de Bioquimica Clinica, Facultad de Quimica, Universidad de la Republica, Montevideo (Uruguay); Pacheco, Jose P. [Instituto de Patobiologia, Facultad de Veterinaria, Universidad de la Republica, Montevideo (Uruguay); Savio, Eduardo [Catedra de Radioquimica, Departamento Estrella Campos, Facultad de Quimica, Universidad de la Republica, P.O. 11800, Montevideo (Uruguay)

    2011-02-15

    Introduction: There are many diseases associated with variations in the expression of apoptosis such as organ rejection after transplantation, myocardial ischemia or infarct and neurodegenerative diseases. For this reason, the early visualization of this process is relevant to set fast and effective therapeutic strategies. Methods: The precursor was prepared according to the procedure reported by R. Alberto, R. Schibli, P. Schubiger, U. Abram, and T. Kaden [Reactions with the technetium and rhenium carbonyl complexes (NEt{sub 4})[MX{sub 3}(CO){sub 3}]. Synthesis and structure of Tc(CN-But){sub 3}(CO){sub 3}](NO{sub 3}) and (Net{sub 4})[Tc{sub 2}({mu}-SCH{sub 2}CH{sub 2}OH){sub 3}(CO){sub 3}], Polyhedron 1996;15: 1079-89]. Recombinant annexin V was incubated with [{sup 99m}Tc](H{sub 2}O)3(CO){sub 3}{sup +} solution, previously neutralized with buffer. Biodistribution studies were performed in 8-week-old female Wistar rats. Animals were housed and treated in compliance with institutional guidelines related to animal experimentation. Work protocol was previously approved by the Animal Ethics Committee of the university. Two groups of rats were defined. One was used as control and the other group was previously injected with 150 mg/kg ip of cyclophosphamide to induce apoptosis. Results: The synthesis of carbonyl precursor achieved yields higher than 90%, and the radiolabeled protein was obtained with 92% of radiochemical purity and high stability in vitro. An important uptake in apoptotic tissues was confirmed by biodistributions, scintigraphic images and histological studies. Conclusions: Biodistribution studies revealed hepatobiliary elimination, high stability in vivo and important uptake in the reticuloendothelial system. In the pathologic model, higher uptake values correspond to the liver, spleen, lungs and femur. Histological studies confirmed the development of apoptosis at 8 and 24 h postinduction in the spleen and lymphocyte bulks in the peribronchial area

  14. Reproductive capability is associated with lifespan and cause of death in companion dogs.

    Science.gov (United States)

    Hoffman, Jessica M; Creevy, Kate E; Promislow, Daniel E L

    2013-01-01

    Reproduction is a risky affair; a lifespan cost of maintaining reproductive capability, and of reproduction itself, has been demonstrated in a wide range of animal species. However, little is understood about the mechanisms underlying this relationship. Most cost-of-reproduction studies simply ask how reproduction influences age at death, but are blind to the subjects' actual causes of death. Lifespan is a composite variable of myriad causes of death and it has not been clear whether the consequences of reproduction or of reproductive capability influence all causes of death equally. To address this gap in understanding, we compared causes of death among over 40,000 sterilized and reproductively intact domestic dogs, Canis lupus familiaris. We found that sterilization was strongly associated with an increase in lifespan, and while it decreased risk of death from some causes, such as infectious disease, it actually increased risk of death from others, such as cancer. These findings suggest that to understand how reproduction affects lifespan, a shift in research focus is needed. Beyond the impact of reproduction on when individuals die, we must investigate its impact on why individuals die, and subsequently must identify the mechanisms by which these causes of death are influenced by the physiology associated with reproductive capability. Such an approach may also clarify the effects of reproduction on lifespan in people. PMID:23613790

  15. Animal facilities

    International Nuclear Information System (INIS)

    The animal facilities in the Division are described. They consist of kennels, animal rooms, service areas, and technical areas (examining rooms, operating rooms, pathology labs, x-ray rooms, and 60Co exposure facilities). The computer support facility is also described. The advent of the Conversational Monitor System at Argonne has launched a new effort to set up conversational computing and graphics software for users. The existing LS-11 data acquisition systems have been further enhanced and expanded. The divisional radiation facilities include a number of gamma, neutron, and x-ray radiation sources with accompanying areas for related equipment. There are five 60Co irradiation facilities; a research reactor, Janus, is a source for fission-spectrum neutrons; two other neutron sources in the Chicago area are also available to the staff for cell biology studies. The electron microscope facilities are also described

  16. [Dangerous animals].

    Science.gov (United States)

    Hasle, Gunnar

    2002-06-30

    As travellers seek ever more exotic destinations they are more likely to encounter dangerous animals. Compared to risks such as AIDS, traffic accidents and malaria, the risk is not so great; many travellers are, however, concerned about this and those who give pre-travel vaccines and advice should know something about it. This article is mainly based on medical and zoological textbooks. Venomous stings and bites may be prevented by adequate clothing and by keeping safe distance to the animals. Listening to those who live in the area is of course important. Travellers should not carry antisera with them, but antisera should be available at local hospitals. It should be borne in mind that plant eaters cause just as many deaths as large predators. In some cases it is necessary to carry a sufficiently powerful firearm. PMID:12555616

  17. Reproductive Market Values Explain Post-reproductive Lifespans in Men.

    Science.gov (United States)

    Vinicius, Lucio; Migliano, Andrea Bamberg

    2016-03-01

    Post-reproductive lifespans (PRLSs) of men vary across traditional societies. We argue that if sexual selection operates on male age-dependent resource availability (or 'reproductive market values') the result is variation in male late-life reproduction across subsistence systems. This perspective highlights the uniqueness of PRLS in both women and men. PMID:26774275

  18. Male Reproductive Toxicology: Environmental Exposures vs Reproductive Competence

    Science.gov (United States)

    Like the lecture this chapter begins with an overview of male reproductive biology and transitions into male reproductive toxicology. It ends with a brief discussion of the strengths and weaknesses in male reproductive toxicology and epidemiology today. This chapter is highly il...

  19. The More the Merrier?. Entropy and Statistics of Asexual Reproduction in Freshwater Planarians

    Science.gov (United States)

    Quinodoz, Sofia; Thomas, Michael A.; Dunkel, Jörn; Schötz, Eva-Maria

    2011-04-01

    The trade-off between traits in life-history strategies has been widely studied for sexual and parthenogenetic organisms, but relatively little is known about the reproduction strategies of asexual animals. Here, we investigate clonal reproduction in the freshwater planarian Schmidtea mediterranea, an important model organism for regeneration and stem cell research. We find that these flatworms adopt a randomized reproduction strategy that comprises both asymmetric binary fission and fragmentation (generation of multiple offspring during a reproduction cycle). Fragmentation in planarians has primarily been regarded as an abnormal behavior in the past; using a large-scale experimental approach, we now show that about one third of the reproduction events in S. mediterranea are fragmentations, implying that fragmentation is part of their normal reproductive behavior. Our analysis further suggests that certain characteristic aspects of the reproduction statistics can be explained in terms of a maximum relative entropy principle.

  20. Animal Locomotion

    CERN Document Server

    Taylor, Graham K; Tropea, Cameron

    2010-01-01

    This book provides a wide-ranging snapshot of the state-of-the-art in experimental research on the physics of swimming and flying animals. The resulting picture reflects not only upon the questions that are of interest in current pure and applied research, but also upon the experimental techniques that are available to answer them. Doubtless, many new questions will present themselves as the scope and performance of our experimental toolbox develops over the coming years.

  1. Impact of the environment on reproductive health.

    Science.gov (United States)

    1991-01-01

    The WHO workshop on the impact of the environment on reproductive health is summarized. Topics include the nature of environmental factors affecting reproductive health, environmental factors blamed for declining sperm quantity and quality, the effects of natural and man-made disasters on reproductive health, chemical pollutants, how the environment damages reproductive health, and research needs for better research methodologies and surveillance data. Recommendations are made to: 1) promote international research collaboration with an emphasis on consistency of methodological approaches for assessing developmental and reproductive toxicity, on development of improved surveillance systems and data bases, an strengthening international disaster alert and evaluation systems; 2) promote research capabilities for multidisciplinary studies, for interactive studies of the environment and cellular processes, and for expansion of training and education; and 3) take action on priority problems of exposure to chemical, physical, and biological agents, of exposure to pesticides among specific populations, and of inadequate screening methods for identification of environmental chemicals. The costs of environmental injury to reproduction include subfertility, intrauterine growth retardation, spontaneous abortion, and various birth defects. Developed country's primary threats are from chemical pollution, radiation, and stress. There is a large gap in knowledge. Caution is urged in understanding the direct relationship between environmental causes and infertility. Sexual health is difficult to assess and research is suggested. Exposure to excessive vitamin A and toxic chemicals are cited as agents probably having serious effects on malformations. Sperm quality has declined over the decades; there is speculation about the potential causes. The effects of radiation such as at Chernobyl are described. Toxic chemical exposure such as in Bhopal, India killed thousands. Neurological

  2. Preparing for Assisted Reproductive Technology

    Science.gov (United States)

    ... CDC Cancel Submit Search The CDC Assisted Reproductive Technology (ART) Note: Javascript is disabled or is not ... visit this page: About CDC.gov . Assisted Reproductive Technology (ART) What Is ART Patient Resources Preparing for ...

  3. REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY OF CONTAMINANTS IN OVIPAROUS ANIMALS

    Science.gov (United States)

    Ecological risk assessments can utilize endpoints at any of a number of biological levels of organization. Except in the case of rare and endangered species, assessment endpoints of most concern in ecological risk assessment typically are at the population and community levels. ...

  4. Animal husbandry and experimental design.

    Science.gov (United States)

    Nevalainen, Timo

    2014-01-01

    If the scientist needs to contact the animal facility after any study to inquire about husbandry details, this represents a lost opportunity, which can ultimately interfere with the study results and their interpretation. There is a clear tendency for authors to describe methodological procedures down to the smallest detail, but at the same time to provide minimal information on animals and their husbandry. Controlling all major variables as far as possible is the key issue when establishing an experimental design. The other common mechanism affecting study results is a change in the variation. Factors causing bias or variation changes are also detectable within husbandry. Our lives and the lives of animals are governed by cycles: the seasons, the reproductive cycle, the weekend-working days, the cage change/room sanitation cycle, and the diurnal rhythm. Some of these may be attributable to routine husbandry, and the rest are cycles, which may be affected by husbandry procedures. Other issues to be considered are consequences of in-house transport, restrictions caused by caging, randomization of cage location, the physical environment inside the cage, the acoustic environment audible to animals, olfactory environment, materials in the cage, cage complexity, feeding regimens, kinship, and humans. Laboratory animal husbandry issues are an integral but underappreciated part of investigators' experimental design, which if ignored can cause major interference with the results. All researchers should familiarize themselves with the current routine animal care of the facility serving them, including their capabilities for the monitoring of biological and physicochemical environment. PMID:25541541

  5. Female Reproductive System.

    Science.gov (United States)

    Hodge, N. J.

    This autoinstructional lesson can be used with health education and/or biology classes in a high school curriculum. It deals with the study of human development with emphasis on the female reproductive organs and cycles. The behavioral objectives are given, and the materials and equipment needed to gain these objectives are itemized. Fifteen…

  6. Selective Reproductive Technologies

    DEFF Research Database (Denmark)

    Gammeltoft, Tine; Wahlberg, Ayo

    2014-01-01

    From a historical perspective, selective reproduction is nothing new. Infanticide, abandonment, and selective neglect of children have a long history, and the widespread deployment of sterilization and forced abortion in the twentieth century has been well documented. Yet in recent decades...

  7. Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine

    DEFF Research Database (Denmark)

    Toft, Gunnar; Lenters, Virissa; Vermeulen, Roel;

    2013-01-01

    Animal and a few human studies suggest that polybrominated diphenyl ethers (PBDEs) may affect male reproductive function. The aim of the present study was to evaluate if male reproductive function was associated with serum level of PBDEs. We evaluated, in a cross-sectional study, the effects of e...

  8. Animal Drug Safety FAQs

    Science.gov (United States)

    ... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Animal & Veterinary Home Animal & Veterinary Safety & Health Frequently Asked Questions Animal Drug Safety Frequently Asked Questions Share Tweet Linkedin ...

  9. Telomeres and reproductive aging.

    Science.gov (United States)

    Keefe, David L; Liu, Lin

    2009-01-01

    Infertility, miscarriage and aneuploid offspring increase with age in women, and meiotic dysfunction underlies reproductive aging. How aging disrupts meiotic function in women remains unclear, but as women increasingly delay having children, solving this problem becomes an urgent priority. Telomeres consist of a (TTAGGG)(n) repeated sequence and associated proteins at chromosome ends, mediate aging in mitotic cells and may also mediate aging during meiosis. Telomeres shorten both during DNA replication and from the response to oxidative DNA damage. Oocytes do not divide in adult mammals, but their precursors do replicate during fetal oogenesis; eggs ovulated from older females have traversed more mitotic cell cycles before entering meiosis during fetal oogenesis than eggs ovulated from younger females. Telomeres also would be expected to shorten from inefficient DNA repair of oxidative damage, because the interval between fetal oogenesis and ovulation is exceptionally prolonged in women. We have tested the hypothesis that telomere shortening disrupts meiosis by shortening telomeres experimentally in mice, which normally do not exhibit age-related meiotic dysfunction. Interestingly, mouse telomeres are much longer than human telomeres, but genetic or pharmacological shortening of mouse telomeres recapitulates in mice the human reproductive aging phenotype as the mouse telomeres reach the length of telomeres from older women. These observations led us to propose a telomere theory of reproductive aging. Moreover, chronological oxidative stress increases with reproductive aging, leading to DNA damage preferentially at (TTAGGG)(n) repeats. Finally, if telomeres shorten with aging, how do they reset across generations? Telomerase could not play a significant role in telomere elongation during early development, because this enzyme is not active until the blastocyst stage, well after the stage when telomere elongation takes place. Rather, telomeres lengthen during the

  10. Gene-environment interaction and male reproductive function

    DEFF Research Database (Denmark)

    Axelsson, Jonatan; Bonde, Jens Peter; Giwercman, Yvonne L;

    2010-01-01

    indicated that specific genotypes may confer a larger risk of male reproductive disorders following certain exposures. This paper presents a critical review of animal and human evidence on how genes may modify environmental effects on male reproductive function. Some examples have been found that support......As genetic factors can hardly explain the changes taking place during short time spans, environmental and lifestyle-related factors have been suggested as the causes of time-related deterioration of male reproductive function. However, considering the strong heterogeneity of male fecundity between...... and within populations, genetic variants might be important determinants of the individual susceptibility to the adverse effects of environment or lifestyle. Although the possible mechanisms of such interplay in relation to the reproductive system are largely unknown, some recent studies have...

  11. Gene-environment interaction and male reproductive function

    DEFF Research Database (Denmark)

    Axelsson, Jonatan; Bonde, Jens Peter; Giwercman, Yvonne L; Rylander, Lars; Giwercman, Aleksander

    2010-01-01

    As genetic factors can hardly explain the changes taking place during short time spans, environmental and lifestyle-related factors have been suggested as the causes of time-related deterioration of male reproductive function. However, considering the strong heterogeneity of male fecundity between...... and within populations, genetic variants might be important determinants of the individual susceptibility to the adverse effects of environment or lifestyle. Although the possible mechanisms of such interplay in relation to the reproductive system are largely unknown, some recent studies have...... indicated that specific genotypes may confer a larger risk of male reproductive disorders following certain exposures. This paper presents a critical review of animal and human evidence on how genes may modify environmental effects on male reproductive function. Some examples have been found that support...

  12. Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes

    Science.gov (United States)

    Adverse trends in male reproductive health have been reported for increased rates of testicular germ cell tumor, low semen quality, cryptorchidism, and hypospadias. An association with prenatal environmental exposure has been inferred from human and animal studies underlying male...

  13. Investigating Climate Change and Reproduction: Experimental Tools from Evolutionary Biology

    Directory of Open Access Journals (Sweden)

    Oliver Y. Martin

    2012-09-01

    Full Text Available It is now generally acknowledged that climate change has wide-ranging biological consequences, potentially leading to impacts on biodiversity. Environmental factors can have diverse and often strong effects on reproduction, with obvious ramifications for population fitness. Nevertheless, reproductive traits are often neglected in conservation considerations. Focusing on animals, recent progress in sexual selection and sexual conflict research suggests that reproductive costs may pose an underestimated hurdle during rapid climate change, potentially lowering adaptive potential and increasing extinction risk of certain populations. Nevertheless, regime shifts may have both negative and positive effects on reproduction, so it is important to acquire detailed experimental data. We hence present an overview of the literature reporting short-term reproductive consequences of exposure to different environmental factors. From the enormous diversity of findings, we conclude that climate change research could benefit greatly from more coordinated efforts incorporating evolutionary approaches in order to obtain cross-comparable data on how individual and population reproductive fitness respond in the long term. Therefore, we propose ideas and methods concerning future efforts dealing with reproductive consequences of climate change, in particular by highlighting the advantages of multi-generational experimental evolution experiments.

  14. Environmental color affects Nile tilapia reproduction

    Directory of Open Access Journals (Sweden)

    Volpato G.L.

    2004-01-01

    Full Text Available We investigated the effects of environmental color on the reproductive behavior of Nile tilapia, Oreochromis niloticus. Two environmental colors were tested by covering the aquarium (60 x 60 x 40 cm with white (12 groups or blue (13 groups cellophane and observing reproductive behavior in groups of 2 males (10.27 ± 0.45 cm and 3 females (10.78 ± 0.45 cm each. After assignment to the respective environmental color (similar luminosity = 100 to 120 Lux, the animals were observed until reproduction (identified by eggs in the female's mouth or up to 10 days after the first nest building. Photoperiod was from 6:00 h to 18:00 h every day. Food was offered in excess once a day and water quality was similar among aquaria. Daily observations were made at 8:00, 11:00, 14:00 and 17:00 h regarding: a latency to the first nest, b number of nests, c gravel weight removed (the male excavates the nest in the bottom of the aquarium, d nest area, and e mouthbrooding incubation (indication of reproduction. The proportion of reproducing fish was significantly higher (6 of 13 in the group exposed to the blue color compared the group exposed to the white color (1 of 12; Goodman's test of proportions. Moreover, males under blue light removed significantly larger masses of gravel (blue = 310.70 ± 343.50 g > white = 130.38 ± 102.70 g; P = 0.01 and constructed wider nests (blue = 207.93 ± 207.80 cm² > white = 97.68 ± 70.64 cm²; P = 0.03 than the control (white. The other parameters did not differ significantly between light conditions. We concluded that reproduction in the presence of blue light was more frequent and intense than in the presence of white light.

  15. Developmental stress increases reproductive success in male zebra finches.

    Science.gov (United States)

    Crino, Ondi L; Prather, Colin T; Driscoll, Stephanie C; Good, Jeffrey M; Breuner, Creagh W

    2014-11-22

    There is increasing evidence that exposure to stress during development can have sustained effects on animal phenotype and performance across life-history stages. For example, developmental stress has been shown to decrease the quality of sexually selected traits (e.g. bird song), and therefore is thought to decrease reproductive success. However, animals exposed to developmental stress may compensate for poor quality sexually selected traits by pursuing alternative reproductive tactics. Here, we examine the effects of developmental stress on adult male reproductive investment and success in the zebra finch (Taeniopygia guttata). We tested the hypothesis that males exposed to developmental stress sire fewer offspring through extra-pair copulations (EPCs), but invest more in parental care. To test this hypothesis, we fed nestlings corticosterone (CORT; the dominant avian stress hormone) during the nestling period and measured their adult reproductive success using common garden breeding experiments. We found that nestlings reared by CORT-fed fathers received more parental care compared with nestlings reared by control fathers. Consequently, males fed CORT during development reared nestlings in better condition compared with control males. Contrary to the prediction that developmental stress decreases male reproductive success, we found that CORT-fed males also sired more offspring and were less likely to rear non-genetic offspring compared with control males, and thus had greater overall reproductive success. These data are the first to demonstrate that developmental stress can have a positive effect on fitness via changes in reproductive success and provide support for an adaptive role of developmental stress in shaping animal phenotype. PMID:25297860

  16. Animated war

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2012-01-01

    in production: Gzim Rewind (Sweden, 2011) by Knutte Wester, and In-World War (USA, expected 2011) by DJ Bad Vegan. These films have themes of war and include film scenes that are ‘machinima’ (real-time animation made in 3D graphic environments) within live action film scenes. Machinima harnesses...... DIY multimedia storytellers explore new ways to tell and to ‘animate’ stories. The article contains four parts: introduction to machinima and the notions of resemiosis and authorial practice, presentation of DIY filmmaking as a practice that intertwines with new networked economics, analysis...

  17. Androgenic endocrine disruptors in wastewater treatment plant effluents in India: Their influence on reproductive processes and systemic toxicity in male rats

    International Nuclear Information System (INIS)

    Endocrine-disrupting chemicals (EDC) are linked to human health and diseases as they mimic or block the normal functioning of endogenous hormones. The present work dealt with a comparative study of the androgenic potential of wastewater treatment plant (WWTP) influents and effluents in Northern region of India, well known for its polluted water. Water samples were screened for their androgenic potential using the Hershberger assay and when they were found positive for androgenicity, we studied their mode of action in intact rats. The data showed a significant change in the weight and structure of sex accessory tissues (SATs) of castrated and intact rats. Reverse transcriptase polymerase chain reaction (RT-PCR) analysis demonstrated a significant change in the expression patterns of the major steroidogenic enzymes in adrenal and testis: cytochrome P450SCC, cytochrome P450C17, 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase. This was further supported by increased enzymatic activities measured in vitro spectrophotometrically. Serum hormone profile showed a decreased level of gonadotrophic hormones and increased testosterone level. Further, increase in the serum level of alkaline phosphatase, SGPT and SGOT and histopathological changes in kidney and liver of treated animals, confirmed the toxic effects of contaminating chemicals. Analysis of water samples using HPLC and GC-MS showed the presence of various compounds and from them, four prominent aromatic compounds viz. nonylphenol, hexachlorobenzene and two testosterone equivalents, were identified. Our data suggest that despite rigorous treatment, the final treated effluent from WWTP still has enough androgenic and toxic compounds to affect general health

  18. 8 CFR 299.4 - Reproduction of Public Use Forms by public and private entities.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Reproduction of Public Use Forms by public... IMMIGRATION REGULATIONS IMMIGRATION FORMS § 299.4 Reproduction of Public Use Forms by public and private... reproduced. Such reproduction must be by an appropriate duplicating process and at the expense of the...

  19. Animal Production and Health Newsletter. No. 13

    International Nuclear Information System (INIS)

    This newsletter includes reports of FAO/IAEA-organized meetings held between 17 September 1990 and 23 November 1990, with emphasis on the development and application of radioimmunoassay and enzyme-linked immunosorbent assay techniques to study Foot and Mouth Disease, bluetongue vins and other diseases, and animal reproduction. The status of existing coordinated research programmes is summarized, and a new coordinated research programme on the development of supplementation strategies for milk-producing animals in tropical and subtropical environments is announced. Applications for contracts to participate in this programme are invited. The role of the Section's Animal Production Unit at Seibersdorf is reviewed, and a list of forthcoming events is given

  20. Laparoscopy-promising tool for improvement of reproductive efficiency of small ruminants

    OpenAIRE

    Dovenski Toni; Trojacanec Plamen; Petkov Vladimir; Popovska-Percinic Florina; Kocoski Ljupce; Grizelj Juraj

    2012-01-01

    Assisted reproductive technologies are used to accelerate genetic gain and improve reproductive performances in farm animals, including small ruminants. This technologies include estrous synchronization, artifi cial insemination (AI) using fresh, frozen or sexed semen, embryo transfer (ET) using in vivo or in vitro produced embryos, and more advanced - cloning and production of transgenic animals. Diagnostic procedures, such as ultrasonography and laparoscopy, have been used as additional too...

  1. Non-photoperiodic regulation of reproductive physiology in the flexibly breeding pine siskin (Spinus pinus)

    OpenAIRE

    Watts, Heather E.; Hahn, Thomas P

    2012-01-01

    In order to time reproduction to coincide with favorable conditions, animals use environmental cues to up- and down-regulate the reproductive axis appropriately. Although photoperiodic cues are one of the best studied of such environmental cues, animals also attend to others such as temperature, food availability, rainfall and social cues. Such non-photic cues are expected to be particularly important for tropical species and temperate-zone species that exhibit flexible or opportunistic breed...

  2. Reproductive Disorder Studies Using Radioimmunoassay (RIA) Progesterone Technique

    International Nuclear Information System (INIS)

    Five dairy cattle, cattle A: 6th parity; cattle B: 7th parity; cattle C: 2nd parity; cattle D and F: 3rd parity, were used in this study. According to Health Extension and Artificial Insemination Technicians anamneses and according to farmers who own the animals, these cattle were showing reproductive failure, and RIA technique was used to study the symptoms. For this purpose, milk progesterone sample were collected twice a week for five weeks to follow the biological reproductive status of every animal. Result from the analysis were plotted for each individual animal and shows that cattle A and B were acyclic, which indicated that no reproductive activity post partum have occurred in both animals; cattle C in the status of prolonged oestrus cycle post partum; and cattle D and F were in the status of recovery of oestrus cycle post partum. With the availability of historical record of the cattle and confirmation of biological status by Health Technicians, the reproductive disorder, which leads to the failure of AI in dairy cattle, can be monitored by RIA Progesterone technique. (author)

  3. Female post-reproductive lifespan: a general mammalian trait.

    Science.gov (United States)

    Cohen, Alan A

    2004-11-01

    Traditional explanations for the evolution of menopause and post-reproductive lifespan in human females have been based on the benefits of maternal or grand-maternal care outweighing the cost of lost reproduction. These explanations assume an evolutionary origin of menopause since human divergence with the most recent common ancestor. In this study, I conduct a literature survey of studies of 42 mammal species from eight orders, showing that post-reproductive lifespan appears to be widespread among mammals. I then propose an alternative to traditional hypotheses: following accepted theories of trade-offs and senescence, I suggest that the cost of extending reproductive lifespan might be relatively high in female mammals. Somatic and reproductive senescence appear to follow separate trajectories, so it is not surprising that the two processes should occur on different schedules. The timing of each process is probably determined by maximization of reproductive performance and survival early in adulthood, with consequent trajectories resulting in a post-reproductive lifespan. The early end of reproduction relative to lifespan may be due to the cost of production and/or maintenance of oocytes, which decline exponentially over time. Oocyte number below a threshold may trigger an end to normal hormonal cycling. PMID:15682868

  4. Platelet-rich plasma and skeletal muscle healing: a molecular analysis of the early phases of the regeneration process in an experimental animal model.

    Directory of Open Access Journals (Sweden)

    Ivan Dimauro

    Full Text Available Platelet-rich plasma (PRP has received increasing interest in applied medicine, being widely used in clinical practice with the aim of stimulating tissue healing. Despite the reported clinical success, there is still a lack of knowledge when considering the biological mechanisms at the base of the activity of PRP during the process of muscle healing. The aim of the present study was to verify whether the local delivery of PRP modulates specific molecular events involved in the early stages of the muscle regeneration process. The right flexor sublimis muscle of anesthetized Wistar rats was mechanically injured and either treated with PRP or received no treatment. At day 2 and 5 after surgery, the animals were sacrificed and the muscle samples evaluated at molecular levels. PRP treatment increased significantly the mRNA level of the pro-inflammatory cytokines IL-1β, and TGF-β1. This phenomenon induced an increased expression at mRNA and/or protein levels of several myogenic regulatory factors such as MyoD1, Myf5 and Pax7, as well as the muscular isoform of insulin-like growth factor1 (IGF-1Eb. No effect was detected with respect to VEGF-A expression. In addition, PRP application modulated the expression of miR-133a together with its known target serum response factor (SRF; increased the phosphorylation of αB-cristallin, with a significant improvement in several apoptotic parameters (NF-κB-p65 and caspase 3, indexes of augmented cell survival. The results of the present study indicates that the effect of PRP in skeletal muscle injury repair is due both to the modulation of the molecular mediators of the inflammatory and myogenic pathways, and to the control of secondary pathways such as those regulated by myomiRNAs and heat shock proteins, which contribute to proper and effective tissue regeneration.

  5. Storyboarding an Animated Film

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2009-01-01

    This paper applies notions of transformation to the analysis of data on semiotic processes related to making an animated film. The data derives from a study conducted in an upper secondary school in Copenhagen with students (18 years old) participating in a week-long workshop. The paper applies the...

  6. From Spirit's Perspective (Animation)

    Science.gov (United States)

    2004-01-01

    This animation shows the perspective from the navigation camera on the Mars Exploration Rover Spirit before and after its automated stand-up process. After standing up, the rover is approximately 12 inches higher off of the lander, resulting in a better view of the surrounding terrain.

  7. Can chemical structure predict reproductive toxicity?

    OpenAIRE

    Maslankiewicz L; Hulzebos EM; Vermeire TG; Muller JJA; Piersma AH; SEC

    2005-01-01

    Structure-Activity Relationships (SARs), including Quantitative SARs, are applied to the hazard assessment of chemicals. This need is all the more urgent considering the proposed new EU policy on chemicals in REACH, which stresses the need for non-animal testing. DEREKfW and the TSCA Chemical Category List of the New Chemicals Program of the US-EPA were chosen to predict reproductive toxicity for REACH purposes. DEREKfW is a software program predicting the toxicological properties using the l...

  8. Personality and reproductive fitness.

    Science.gov (United States)

    Eaves, L J; Martin, N G; Heath, A C; Hewitt, J K; Neale, M C

    1990-09-01

    The relationship between reproductive success (number of biological children) and personality was explored in 1101 postmenopausal females from the Australian twin registry. The quadratic response surface relating fitness to extraversion (E) and neuroticism (N) showed a saddle point at intermediate levels of E and N. Selection was shown to be stabilizing, i.e., having an intermediate optimum, along the axis low E, low N-high E, high N and more mildly disruptive, having greater fitness in the extremes, along the axis low N, high E-high N, low E. Neither dimension of personality considered by itself showed a significant linear or quadratic relationship to reproductive success. Sections through the fitness surface, however, show selection tends to favor high neuroticism levels in introverts and low neuroticism levels in extroverts. PMID:2288546

  9. Animal Models of Atherosclerosis

    OpenAIRE

    Godfrey S Getz; Reardon, Catherine A

    2012-01-01

    Atherosclerosis is a chronic inflammatory disorder that is the underlying cause of most cardiovascular disease. Both cells of the vessel wall and cells of the immune system participate in atherogenesis. This process is heavily influenced by plasma lipoproteins, genetics and the hemodynamics of the blood flow in the artery. A variety of small and large animal models have been used to study the atherogenic process. No model is ideal as each has its own advantages and limitations with respect to...

  10. Mitochondria and mammalian reproduction

    OpenAIRE

    Ramalho-Santos, J; Amaral, Sandra

    2013-01-01

    Mitochondria are cellular organelles with crucial roles in ATP synthesis, metabolic integration, reactive oxygen species (ROS) synthesis and management, the regulation of apoptosis (namely via the intrinsic pathway), among many others. Additionally, mitochondria in different organs or cell types may have distinct properties that can decisively influence functional analysis. In terms of the importance of mitochondria in mammalian reproduction, and although there are species-specifi...

  11. Interventions in reproduction.

    Science.gov (United States)

    Sheriff, D S; Sheriff, S Omer

    2006-01-01

    Assisted reproductive technology has helped many childless couples. It has also raised questions about how appropriate the technology might be in different situations. How we understand parenthood is crucial in taking a stand on such scientific intervention. It is suggested that physicians should decide on offering artificial insemination, surrogacy and in-vitro fertilisation only after considering if the child will have good parents and if there will be legal complications from the use of the technology. PMID:17223683

  12. A Perspective on the Importance of Reproductive Mode in Astrobiology

    Science.gov (United States)

    Van Doninck, Karine; Schön, Isa; Martens, Koen

    2003-12-01

    Reproduction is a vital characteristic of life, and sex is the most common reproductive mode in the eukaryotic world. Sex and reproduction are not necessarily linked mechanisms: Sexuality without reproduction exists, while several forms of asexual reproduction are known. The occurrence of sexuality itself is paradoxical, as it is very costly in evolutionary terms. Most of the hypotheses (more than 20) attempting to explain the prevalence of sex fall into two categories: Sex either creates good gene combinations for adaptation to environments or eliminates bad gene combinations counteracting the accumulation of mutations. In spite of this apparent wealth of beneficial effects of sex, asexuality is not rare. Most eukaryotic, asexual lineages are short-lived and can only persist through the presence of sexual roots, but at least two animal groups, bdelloid rotifers and darwinulid ostracods, seem to claim the status of ancient asexuals. Research on (a)sexuality is relevant to astrobiology in a number of ways. First, strong relationships between the origin and persistence of life in extreme environments and reproductive mode are known. Second, the "habitability" of nonterrestrial environments to life greatly depends on reproductive mode. Whereas asexuals can do equally well or better in harsh environments, they fail to adapt fast enough to changing abiotic and biotic environments. Third, it has been shown that plants reproduce mainly asexually in space, and sperm production and motility in some vertebrates are hampered. Both findings indicate that extraterrestrial life under conditions different from Earth might be dominated by asexual reproduction. Finally, for exchange of biological material between planets, the choice of reproductive mode will be important.

  13. Genomics of reproduction in nematodes: prospects for parasite intervention?

    Science.gov (United States)

    Nisbet, Alasdair J; Cottee, Pauline A; Gasser, Robin B

    2008-02-01

    Understanding reproductive processes in parasitic nematodes has the potential to lead to the informed design of new anthelmintics and control strategies. Little is known, however, about the molecular mechanisms underlying sex determination, gametogenesis and reproductive physiology for most parasitic nematodes. Together with comparative analyses of data for the free-living nematode Caenorhabditis elegans, molecular investigations are beginning to provide insights into the processes involved in reproduction and development in parasitic nematodes. Here, we review recent developments, focusing on technological aspects and on molecules associated with sex-specific differences in adult nematodes. PMID:18182326

  14. EFFECTS OF CADMIUM ON THE REPRODUCTIVE AXIS OF JAPANESE MEDAKA

    Science.gov (United States)

    Cadmium (Cd) is a ubquitous element and a significant inorganic pollutant that has previously been found to bioaccumulate in reproductive organs of fish and disrupt important endocrine processes, especially those involved in synthesis, release and metabolism of hormones. Clearly,...

  15. [Reproductive or domestic work].

    Science.gov (United States)

    Larranaga, I; Arregui, B; Arpal, J

    2004-05-01

    The objective of this article is to describe the evolution of reproductive work and to analyse those factors related to its distribution. The analysis has been based on data from various Time-use Surveys (Women Institute 1993, 1996, 2001) as well as on data from different regional surveys: Andalusia, the Basque Country, Madrid and the metropolitan area of Barcelona. In the period 1993-2001, the amount of time devoted by men to housekeeping in Spain increased by 35% while women's time declined by 5%. Yet, in 2001 women's dedication to housekeeping was twice that of men's (7.2 vs 3.1 h daily). However, the imbalance in sharing of housework declined among younger people. Union formation and growing family size increase women's housework intensifying the uneven distribution of household chores. When women are employed and have higher educational and income levels, dedication to household tasks decreases and gender inequalities are reduced. In spite of growing male participation in housework, reproductive work is still mainly women's responsibility. The recent legal, social and cultural changes have not been able to eradicate the traditional model of assigning reproductive work in the home. PMID:15171855

  16. Bioethical Problems: Animal Welfare, Animal Rights.

    Science.gov (United States)

    March, B. E.

    1984-01-01

    Discusses various bioethical issues and problems related to animal welfare and animal rights. Areas examined include: Aristotelian views; animal welfare legislation; Darwin and evolutionary theory; animal and human behavior; and vegetarianism. A 14-point universal declaration of the rights of animals is included. (JN)

  17. Life-history tradeoffs and reproductive cycles in Spotted Owls

    Science.gov (United States)

    Stoelting, Ricka E.; Gutierrez, R.J.; Kendall, William; Peery, M. Zachariah

    2015-01-01

    The study of tradeoffs among life-history traits has long been key to understanding the evolution of life-history strategies. However, more recently, evolutionary ecologists have realized that reproductive costs have the potential to influence population dynamics. Here, we tested for costs of reproduction in the California Spotted Owl (Strix occidentalis occidentalis), and assessed whether costs of reproduction in year t − 1 on reproduction in year t could be responsible for regionally synchronized biennial cycles in reproductive output. Logistic regression analysis and multistate mark–recapture models with state uncertainty revealed that breeding reduced the likelihood of reproducing in the subsequent year by 16% to 38%, but had no influence on subsequent survival. We also found that costs of reproduction in year t − 1 were correlated with climatic conditions in year t, with evidence of higher costs during the dry phase of the El Niño–Southern Oscillation. Using a simulation-based population model, we showed that strong reproductive costs had the potential to create biennial cycles in population-level reproductive output; however, estimated costs of reproduction appeared to be too small to explain patterns observed in Spotted Owls. In the absence of strong reproductive costs, we hypothesize that observed natural cycles in the reproductive output of Spotted Owls are related to as-yet-unmeasured, regionally concordant fluctuations in environmental conditions or prey resources. Despite theoretical evidence for demographic effects, our analyses illustrate that linking tradeoffs to actual changes in population processes will be challenging because of the potential confounding effects of individual and environmental variation.

  18. Peptides: Basic determinants of reproductive functions.

    Science.gov (United States)

    Celik, Onder; Aydin, Suleyman; Celik, Nilufer; Yilmaz, Musa

    2015-10-01

    Mammalian reproduction is a costly process in terms of energy consumption. The critical information regarding metabolic status is signaled to the hypothalamus mainly through peripheral peptides from the adipose tissue and gastrointestinal tract. Changes in energy stores produce fluctuations in leptin, insulin, ghrelin and glucose signals that feedback mainly to the hypothalamus to regulate metabolism and fertility. In near future, possible effects of the nutritional status on GnRH regulation can be evaluated by measuring serum or tissue levels of leptin and ghrelin in patiens suffering from infertility. The fact that leptin and ghrelin are antagonistic in their effects on GnRH neurons, their respective agonistic and antagonistic roles make them ideal candidates to use instead of GnRH agonist and antagonist. Similarly, kisspeptin expressing neurons are likely to mediate the well-established link between energy balance and reproductive functions. Exogenous kisspeptin can be used for physiological ovarian hyperstimulation for in-vitro fertilization. Moreover, kisspeptin antagonist therapy can be used for the treatment of postmenapousal women, precocious puberty, PCOS, endometriosis and uterine fibroids. In this review, we will analyze the central mechanisms involved in the integration of metabolic information and their contribution to the control of the reproductive function. Particular attention will be paid to summarize the participation of leptin, kisspeptin, ghrelin, NPY, orexin, urocortin, VIP, insulin, galanin, galanin like peptide, oxytocin, agouti gene-related peptide, and POMC neurons in this process and their possible interactions to contribute to the metabolic control of reproduction. PMID:26074346

  19. Behavioural reproductive isolation and speciation in Drosophila

    Indian Academy of Sciences (India)

    Punita Nanda; Bashisth Narayan Singh

    2012-06-01

    The origin of premating reproductive isolation continues to help elucidate the process of speciation and is the central event in the evolution of biological species. Therefore, during the process of species formation the diverging populations must acquire some means of reproductive isolation so that the genes from one gene pool are prevented from dispersing freely into a foreign gene pool. In the genus Drosophila, the phenomenon of behavioural reproductive isolation, which is an important type of premating (prezygotic) reproductive isolating mechanisms, has been extensively studied and interesting data have been documented. In many cases incomplete sexual isolation has been observed and the pattern and degree of isolation within and between the species have often been used to elucidate the phylogenetic relationships. The present review documents an overview of speciation mediated through behavioural incompatibility in different species groups of Drosophila with particular reference to the models proposed on the basis of one-sided ethological isolation to predict the direction of evolution. This study is crucial for understanding the mechanism of speciation through behavioural incompatibility and also for an understanding of speciation genetics in future prospects.

  20. Study of the main body dimensions that are used in the selection process, in the reproductive nucleus of the Romanian Sport Horse from Jegălia studfarm

    Directory of Open Access Journals (Sweden)

    Mariana Vodă Girlea Mariana

    2013-10-01

    Full Text Available Study of average performances in a population have a huge importance because, regarding to a population, the average of phenotypic value is equal with average of genotypic value. So, the studies of the average value of characters offer us an idea about the population genetic level. This study have the principal purpose to analyse main body dimensions who are used in selection process: withers height, thoracyc perimether and cannon bone perimether, through the integration of individs in an evaluation class, in accordance with selection methodology. The biological material is represented by 56 Romanian Sport Horses, 4 males and 52 females, at different ages, owned by Jegălia stood farm . The average performances of characters are presented in the paper. We can observe an important grade of variability with some differences between sexes. The average performances of the characters are between characteristic limits of the breed.

  1. Animal cloning: advances and prospects

    Directory of Open Access Journals (Sweden)

    Chuaire Lilian

    2004-05-01

    Full Text Available Few recent advances have revolutionized the developmental biology as the animal cloning has. Since the birth of Dolly, the sheep, in 1996, which was the first derived clone of a mature animal, a new scientific era began. It has been characterized by growing demystification that differentiated cells are unalterable entities in its nuclear organization and chromatin structure, and by a better understanding of the mechanisms that regulate the development. Throughout this paper, we will review some of the achievements and limitations of the techniques used, both in therapeutic and in the reproductive cloning, as well as the perspectives that its application allows to glimpse within a close future. At the same time, we will point out some considerations regarding the ethical debate that surrounds such a controversial issue.

  2. Globalization and reproductive tourism in the United Arab Emirates.

    Science.gov (United States)

    Inhorn, Marcia C; Shrivastav, Pankaj

    2010-07-01

    Over the past 2 decades, the discipline of anthropology has been deeply concerned with the processes and effects of globalization around the world. One of the major anthropological theorists of globalization, Arjun Appadurai, has delineated a "global cultural economy" in which global movements operate through 5 pathways, which he famously called "scapes." This article uses the language of "scapes" to examine the global flows involved in so-called "reproductive tourism," or the search for assisted reproductive technologies across national and international borders. Reproductive tourism entails a complex "reproscape" of moving people, technologies, finance, media, ideas, and gametes, pursued by infertile couples in their "quests for conception." This article examines reproductive tourism to and from the United Arab Emirates, which is now the site of intense globalization and global flows, including individual and population movements for the purposes of reproductive and other forms of medical care. PMID:20566536

  3. Factors determining the reproductive potential of Pelibuey sheep: Effects of season and parturition on reproductive performance

    International Nuclear Information System (INIS)

    The Pelibuey sheep in Mexico are known for their hardiness and reproductive capacity: as a result they represent a reliable source of animal protein especially at the village level. Although their reproductive parameters have been studied, little endocrinological information is available. The objectives of the present study were to characterize the annual reproductive cycle in the Pelibuey ram and ewe, and to study methods of shortening the interval from parturition to first oestrus in lactating post-partum ewes. Under conditions of nutrition and management prevailing in this study, season affected levels of testosterone and LH in the male and LH in the female. Season also influenced oestrous activity, the proportion of ewes ovulating per month and the mean ovulation rate per month. The results indicated that the majority of Pelibuey ewes cycle throughout the year but exhibit reduced gonadal activity during late winter. Pelibuey rams appear to have longer periods of reduced activity (during late autumn and winter), although testosterone levels suggest that rams return to their full reproductive activity earlier (late winter) than ewes. (author). 30 refs, 7 figs, 3 tabs

  4. New biotechnological procedures in swine reproduction

    Directory of Open Access Journals (Sweden)

    Petrujkić Tihomir

    2002-01-01

    Full Text Available New biotechnological procedures and the use of hormones in swine breeding are aimed at increasing the number of piglets in the litter. In small herds and groups, selected sows with 16 mammary complexes (tits can yield up to 32 piglets, or porkers, per year per sow. In order to achieve such reproduction results, special, individual stalls for sow deliveries are used, in addition to biotechnological methods, with a warm core and floor heating, phased diet and clean facilities. The ovulation value in swine is determined by their genetic and paragenetic effects, and it is often provoked and increased with injections and preparations for superovulation. However, the results vary, since any administration of hormone injecions can reduce the reproductive cycle, shorten the duration of estrus, or disrupt the work of ovaries and create cystic follicles. The use of follicle-stimulating hormones in quantities up to 1000 IU per animal for the induction and synchronization of estrus has become customary for sows and gilts, as well as the use of prostaglandins, the use of GnRH for increasing ovulation in swine and increasing the number of follicles >4 mm in diameter in the implementation of new biotechnologies in swine breeding, increases the number of ovulations and fertility in swine. In this way, reproduction is raised to the highest possible level, and artificial insemination of sows has 12 separate rules which enable better and more successful artificial insemination of sows.

  5. Stochastic modelling of animal movement

    OpenAIRE

    Smouse, Peter E.; Focardi, Stefano; Moorcroft, Paul R.; Kie, John G.; Forester, James D.; Morales, Juan M.

    2010-01-01

    Modern animal movement modelling derives from two traditions. Lagrangian models, based on random walk behaviour, are useful for multi-step trajectories of single animals. Continuous Eulerian models describe expected behaviour, averaged over stochastic realizations, and are usefully applied to ensembles of individuals. We illustrate three modern research arenas. (i) Models of home-range formation describe the process of an animal ‘settling down’, accomplished by including one or more focal poi...

  6. Sense and Nonsense in Metabolic Control of Reproduction

    Directory of Open Access Journals (Sweden)

    Jill eSchneider

    2012-03-01

    Full Text Available An exciting synergistic interaction occurs among researchers working at the interface of reproductive biology and energy homeostasis. Reproductive biologists benefit from the theories, experimental designs, and methodologies used by experts on energy homeostasis, and bring context and meaning to the study of energy homeostasis. There is a growing recognition that identification of candidate genes for obesity is little more than meaningless reductionism unless those genes and their expression are placed in a developmental, environmental, and evolutionary context. Reproductive biology provides this context because 1 metabolic energy is the most important factor that controls reproductive success, 2 gonadal hormones affect energy intake, storage and expenditure, 3 reproductive hormone secretion changes during development, and 4 reproductive success is key to evolutionary adaptation, the process that most likely molded the mechanisms that control energy balance. It is likely that by viewing energy intake, storage, and expenditure in the context of reproductive success, we will gain insight into human obesity, eating disorders, diabetes, and other pathologies related to fuel homeostasis.This review emphasizes the metabolic hypothesis: A sensory system monitors the availability of oxidizable metabolic fuels and orchestrates behavioral motivation to optimize reproductive success in environments where energy availability fluctuates or is unpredictable.

  7. Bienestar y reproducción animal

    Directory of Open Access Journals (Sweden)

    Córdova-Izquierdo, Alejandro

    2008-12-01

    Full Text Available It can be defined Animal welfare (AW, as the stage of complete physical and mental health of the animals where is in complete harmony with their atmosphere. The correct well-being should fulfill appropriate requirements as: I manage, food and transport, treatment, prevention of illnesses, appropriate facilities for their development and their comfort. The general objective of the BW, is to avoid the pain or unnecessary suffering above all and to force as much to the proprietors as to the caretakers of animals, torespect minimum requirements of welfare. In this work, aspects related with the strss are approached - answer of the animals in the face of any factor of the environment - that rebound with the welfare and reproductive acting of the domestic mammals in the Units of Animal Production (UAP.

  8. Animal science: Isotopes and nuclear techniques

    International Nuclear Information System (INIS)

    In many regions of the world, animal production is limited by poor growth, reproductive performance and milk output of livestock, thus limiting the availability of animal products such as meat, milk, leather, etc., for use by man. Reduced animal production results from inadequate or unbalanced nutrition, lack of adaptation to climatic conditions, and parasitic and other diseases The production from animals can be improved on the one hand by improving genotypes (the breeds and strains within a given species) to make them better suited to the environment to which they are exposed, and on the other hand by modifying the components of the environment which are limiting the production. In practice, a combination of these two strategies is usually desirable but the relative importance of each is determined by short- and long-term economic considerations and the likely environmental consequences. Isotopes and radiation play an important part in identifying and alleviating the genetic and environmental limitations to animal production

  9. The peculiarity of animal complexes of chernozem

    OpenAIRE

    O. V. Zhukov

    2005-01-01

    The genetic connection of animal complexes and soil cover is in the basis of diagnostic ability of animals to indicate and quantity assessment of soil processes. The ecoiGgical view and peculiarity of soil animal complexes has the most impotent value. The soil animal complexes of steppe and their trans-formation under artificial forest are discussed

  10. Animated nature

    International Nuclear Information System (INIS)

    Animated nature is educational-training project pronounced by the Slovak Environmental Agency (SAZP) in cooperation with Field Studies Council form Great Britain and financial support of Darwin Initiative and Slovensky plynarensky priemysel, s.p. In the present time this is ultimate and the most successful children's project aimed on mapping and protection of biodiversity in Europe. Activity in project is spare-time and therefore is voluntary. The interest territory is a natural as well as cultural landscape in vicinity of a school or other organisation, habitation and so on. In the project work schoolchildren at the age from 10 till 15 years. Leaders of work-groups are student of secondary schools and universities, teachers, professional workers of state and non-governmental organisation and parents. In one group works approximately 10 children. Each group which has send to SAZP result of biodiversity mapping, cost free obtained data base CD - Detske mapy biodiverzity (Children's maps of biodiversity) and so they were informed about results of all groups frame: within the frame of Slovakia. Results of activities of this project in 2001-2004 and perspectives for 2005-2006 years are discussed

  11. Mass and energy budgets of animals: Behavioral and ecological implications

    Energy Technology Data Exchange (ETDEWEB)

    Porter, W.P.

    1993-01-01

    The common goal of these diverse projects is to understand the mechanisms of how animal populations respond to the continual changes in their environment in both time and space. Our models are mechanistic allowing us to explore how a wide array of environmental variables may determine individual performance. Large scale climate change and its effect on animal populations can be seen as quantitative extensions of biological responses to smaller scales of environmental variability. Changes in developmental rates or reproductive levels of individuals, extension or contraction of geographic ranges, and modification of community organization have all been documented in response to previous changes in habitats. We know from our biophysical work that some changes in function are driven by microclimate conditions directly, and some are mediated indirectly through ecological parameters such as the food supply. Our research is guided by a comprehensive conceptual scheme of the interaction of an animal with its environment. The physical and physiological properties of the organism, and the range of available microclimates, set bounds on the performance of organismal function, such as growth, reproduction, storage, and behavior. To leave the most offspring over a lifetime, animals must perform those functions in a way that maximizes the amount of resources devoted to reproduction. Maximizing the total size of the budget and minimizing those budget items not devoted to reproduction are crucial. Animals trade off among expenditures for current and future reproduction. Both water and energy are important, potentially limiting resources. Projects described here include empirical studies and theoretical models.

  12. Investigation on Melting and Reproduction Process of Aluminum Scrap Cans%废铝易拉罐熔炼及其再生工艺的研究

    Institute of Scientific and Technical Information of China (English)

    丁灏; 白培康; 杨晶; 张文达

    2013-01-01

    In the renewable industry aluminum cans recycling and reuse occupy a more important position.The effect of flux components,melting temperature on recovery ratio and impurity content was analyzed.The best combination of optimal purification process obtained by orthogonal experiment is 3# flux components,melting temperature (740 ℃) and flux addition (4%).It can makes recovery ratio increase to 88.6% and impurity content reduce to 0.1065%.The tensile strength and elongation is 193 MPa and 21.04%.%在铝的再生产业中,易拉罐的回收与再利用占有了比较重要的位置.实验研究了熔剂配比、熔炼温度和熔剂加入量对废铝易拉罐再生利用的回收率、含杂量的影响.通过正交试验得到了最优的净化工艺:3#配方熔剂、熔炼温度740℃、熔剂加入量4%的组合,在此条件下废铝易拉罐的回收率为88.6%,含杂量为0.106 5%.其抗拉强度达到193 MPa,伸长率为21.04%.

  13. Animal production and health newsletter, No. 49, January 2009

    International Nuclear Information System (INIS)

    This issue of the Newsletter highlights the upcoming International Symposium on 'Sustainable Improvement of Animal Production and Health' from 8 to 11 June 2009 in Vienna, Austria. The Symposium will address: The early and rapid diagnosis and control methods for transboundary animal diseases including those of a zoonotic nature; Improved reproduction technologies and breeding strategies; The efficient and sustainable use of locally available resources for animal production

  14. Vitamin C partially attenuates male reproductive deficits in hyperglycemic rats

    Directory of Open Access Journals (Sweden)

    Damasceno Débora C

    2011-07-01

    Full Text Available Abstract Background Hyperglycemia can impair the male reproductive system in experimental animals and in men during reproductive age. Studies have shown that vitamin C has some good effects on male reproductive system, and therefore vitamin C treatment could attenuate the dysfunctions in this system caused by hyperglycemia. Thus, the objective of this work was to evaluate whether vitamin C treatment could attenuate reproductive dysfunctions in hyperglycemic male rats. Methods Adult male rats were divided into 3 groups: a normoglycemic (n = 10 and two hyperglycemic (that received a single dose of streptozotocin - 40 mg/kg BW. The two last groups (n = 10 per group were divided into: hyperglycemic control (Hy and hyperglycemic + 150 mg of vitamin C (HyC, by gavage during 30 consecutive days. The normoglycemic and hyperglycemic control groups received the vehicle (water. The first day after the treatment, the rats were anesthetized and killed to evaluate oxidative stress biomarkers (TBARS, SOD, GSHt and GSH-Px in the erythrocytes, body and reproductive organ weights, sperm parameters, plasma hormone levels (FSH, LH and testosterone, testicular and epididymal histo-morphometry and histopathology. Results Compared with the normoglycemic animals, hyperglycemic control rats showed reduced weight of the body and reproductive organ but testis weight was maintained. It was also observed reduction of testosterone and LH levels, seminiferous tubular diameter, sperm motility and sperm counts in the epididymis. In addition, there was an increase in morphological abnormalities on spermatozoa as well as in oxidative stress level. Vitamin C reduced the oxidative stress level, diminished the number of abnormal sperm, and increased testosterone and LH levels and seminiferous tubular diameter but did not show improvement of sperm motility in relation to the hyperglycemic control group. Hyperglycemia caused a rearrangement in the epididymal tissue components (stroma

  15. The role of genomics in conservation and reproductive sciences.

    Science.gov (United States)

    Johnson, Warren E; Koepfli, Klaus

    2014-01-01

    maintaining functional ecosystems, evolutionary process and will impact future food supplies, human health, biomaterial development and geopolitics (Myers and Knoll Proc Natl Acad Sci U S A 98:5389-5392, 2001; Templeton et al. Proc Natl Acad Sci U S A 98:5426-5432, 2001). Therefore, conservation of genetic diversity is a social, cultural, scientific, and economic prerogative and is the key to adaptation in the uncertain future of a human-dominated environment. Once lost, genetic resources are nearly impossible to regain, increasing the urgency of fundamental global approaches (e.g. www.cbd.int/sp/targets ).In this chapter we provide a review of current research and recent advances in biotechnology and genomic approaches for animal conservation and the management of genetic resources, with an emphasis on reproductive sciences. It is intended to provide information and insights for research and to provoke thoughts on how to take advantage of these opportunities. PMID:25091907

  16. Nearby grandmother enhances calf survival and reproduction in Asian elephants

    Science.gov (United States)

    Lahdenperä, Mirkka; Mar, Khyne U.; Lummaa, Virpi

    2016-01-01

    Usually animals reproduce into old age, but a few species such as humans and killer whales can live decades after their last reproduction. The grandmother hypothesis proposes that such life-history evolved through older females switching to invest in their existing (grand)offspring, thereby increasing their inclusive fitness and selection for post-reproductive lifespan. However, positive grandmother effects are also found in non-menopausal taxa, but evidence of their associated fitness effects is rare and only a few tests of the hypothesis in such species exist. Here we investigate the grandmother effects in Asian elephants. Using a multigenerational demographic dataset on semi-captive elephants in Myanmar, we found that grandcalves from young mothers (<20 years) had 8 times lower mortality risk if the grandmother resided with her grandcalf compared to grandmothers residing elsewhere. Resident grandmothers also decreased their daughters’ inter-birth intervals by one year. In contrast to the hypothesis predictions, the grandmother’s own reproductive status did not modify such grandmother benefits. That elephant grandmothers increased their inclusive fitness by enhancing their daughter’s reproductive rate and success irrespective of their own reproductive status suggests that fitness-enhancing grandmaternal effects are widespread, and challenge the view that grandmother effects alone select for menopause coupled with long post-reproductive lifespan. PMID:27282468

  17. Nearby grandmother enhances calf survival and reproduction in Asian elephants.

    Science.gov (United States)

    Lahdenperä, Mirkka; Mar, Khyne U; Lummaa, Virpi

    2016-01-01

    Usually animals reproduce into old age, but a few species such as humans and killer whales can live decades after their last reproduction. The grandmother hypothesis proposes that such life-history evolved through older females switching to invest in their existing (grand)offspring, thereby increasing their inclusive fitness and selection for post-reproductive lifespan. However, positive grandmother effects are also found in non-menopausal taxa, but evidence of their associated fitness effects is rare and only a few tests of the hypothesis in such species exist. Here we investigate the grandmother effects in Asian elephants. Using a multigenerational demographic dataset on semi-captive elephants in Myanmar, we found that grandcalves from young mothers (grandmother resided with her grandcalf compared to grandmothers residing elsewhere. Resident grandmothers also decreased their daughters' inter-birth intervals by one year. In contrast to the hypothesis predictions, the grandmother's own reproductive status did not modify such grandmother benefits. That elephant grandmothers increased their inclusive fitness by enhancing their daughter's reproductive rate and success irrespective of their own reproductive status suggests that fitness-enhancing grandmaternal effects are widespread, and challenge the view that grandmother effects alone select for menopause coupled with long post-reproductive lifespan. PMID:27282468

  18. Bateman revisited: the reproductive tactics of female primates.

    Science.gov (United States)

    Drea, Christine M

    2005-11-01

    The breeding system of an animal population is thought to depend on the ability of one sex (usually the male) to acquire mates, either directly through association with females or indirectly through defense of the resources desired by females. The sex that contributes most to infant care (usually the female) is constrained by parental involvement and thereby limits reproduction of the opposite sex. Accordingly, males, but not females, enhance their reproductive success by acquiring additional mates. This classical view has emphasized the role of male-male competition in sexual selection, at the expense of fully exploring the potential for female choice. A more recent shift in focus has revealed substantial variation in female reproductive success and increasingly accentuates the importance of female intrasexual competition and male mate choice. A comparative review of primate reproduction, therefore, challenges expectations of male control and female compliance, and calls for a comprehensive treatment of costs and benefits that extends beyond conventional mention of heavy female investment versus male negligence or absenteeism. For individuals that manipulate their social environment or reproductive output, consideration of more subtle, even cryptic, aspects of female behavior and physiology (e.g., social strategizing, sexual solicitation or rejection, sexual advertisement or concealed ovulation, multiple mating, and reproductive failure) raises the question of whether females can be effectively 'monopolized.' Widespread patterns that counter Bateman's paradigm call for a reexamination of the predictions generated by dichotomizing gametes into 'expensive eggs' and 'cheap sperm,' and encourage continued mechanistic research focused on conception quality rather than quantity. PMID:21676842

  19. VARIATIONS IN REPRODUCTIVE TOXICANT IDENTIFICATION

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, F

    2008-05-13

    Reproductive toxicants are a very important class of compounds. They present unique hazards to those of child bearing ages, perform their 'dirty work' using a wide variety of mechanisms on a number of different organs, and are regulatorily important. Because of all of this, properly identifying reproductive toxicants is important, but fraught with difficulty. In this paper we will describe types or reproductive toxicants, their importance, and both mistakes and good practices that people who are not experts in reproductive toxicology may use in their attempts to identify them. Additionally, this paper will focus on chemical reproductive toxicants and will not address biological agents that could affect reproductive toxicity although many principles outlined here could be applied to that endeavor.

  20. Gender and Women's Reproductive Health

    OpenAIRE

    Aygul Akyuz; Gonul Sahiner

    2010-01-01

    AIM: According to the “rights to equality” in reproductive and sexual rights, “no persons should be discriminated against their sexual and reproductive lives, in their access to health care and/or services on the grounds of race, sex, sexual orientation, marital status, family position, age, language, religion, political, or other opinion; national or social origin, property, birth, or other status” In this context, health professionals devoted to reproductive health are r...