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Sample records for animal investigation program

  1. Animal Investigation Program: Nevada Test Site and Vicinity. Annual report, 1979

    International Nuclear Information System (INIS)

    Data are presented from the radioanalyses of tissues collected from cattle, mule deer, desert bighorn sheep, rabbits, chukar, golden eagles, and other wildlife that resided on or near the Nevada Test Site during 1979. Routine and special activities of the Animal Investigation Program are also discussed. Other than the naturally occurring potassium-40, gamma-emitting radionuclides were detected infrequently. Strontium-90 concentrations in bones from deer, cattle, and desert bighorn sheep were lower than those of recent years. Tritium concentrations were generally within expected environmental limits with the exception of animals exposed to known sources of contamination; e.g., drainage ponds from Area 12 tunnels or the Sedan Crater. Plutonium levels in all tissues from all species showed little variation to those levels in samples collected in recent years. Radionuclide tissue concentrations were generally higher in the tissues of animals residing in Area 15 than in similar animals collected from other Nevada Test Site areas. Hypothetical annual dose estimates to man were calculated on the basis of the daily consumption of 0.5 kilogra of liver or muscle from animals that contained peak radionuclide levels. The movements of 25 mule deer outfitted with collars containing a radio transmitter unit were monitored on a weekly basis. No gross or microscopic lesions were found in necropsied animals that could be directly attributed to the effects of ionizing radiation

  2. Animal investigation program 1978 annual report: Nevada Test Site and vicinity

    International Nuclear Information System (INIS)

    Data are presented from the radioanalyses of tissues collected from cattle, mule deer, desert bighorn sheep, rabbits, golden eagles, and other wildlife that resided on or near the Nevada Test Site during 1978. Routine and special activities of the Animal Investigation Program are also discussed. Other than the naturally occurring Potassium-40, gamma-emitting radionuclides were detected infrequently with the exception of short-lived radionuclides found in samples from animals collected soon after March 14 (the date of a nuclear test by the People's Republic of China). Strontium-90 concentrations in bones from deer, cattle, and desert bighorn sheep were consistent with those of recent years. Tritium concentrations were generally within expected environmental limits with the exception of animals exposed to sources of contamination; e.g., drainage ponds from Area 12 tunnels. Plutonium levels in all tissues from all species showed little variation from recent years. However, cattle tissue sampled in the fall were higher than those collected in the spring. Radionuclide tissue concentrations were generally higher in the tissues of animals residing in Area 15 than in similar animals collected from other Nevada Test Site areas. Hypothetical dose estimates to man were calculated on the basis of the daily consumption of 0.5 kilogram of liver or muscle from animals that contained peak radionuclide levels. The movements of 13 mule deer outfitted with collars containing a radio transmitter unit were monitored on a weekly basis. No gross or microscopic lesions were found in necropsied animals that could be directly attributed to the effects of ionizing radiation

  3. Animal investigation program 1980 annual report: Nevada Test Site and vicinity

    International Nuclear Information System (INIS)

    Data are presented from the radioanalyses of tissues collected from cattle, mule deer, desert bighorn sheep, rabbits, and a horse that resided on or near the Nevada Test Site during 1980. Routine and special activities of the Animal Investigation Program are also discussed. Other than the naturally occurring 40K, gamma-emitting radionuclides were detected infrequently. 131I was found in the thyroid of a deer 3 weeks after a nuclear test by the People's Republic of China. Concentrations of 90Sr in bones from deer, cattle, and desert bighorn sheep were similar to those of recent years. Plutonium levels in all tissues from all species showed little variation from those levels in samples collected in recent years. Radionuclide concentrations were generally higher in the tissues of animals residing in Area 15 than in similar animals collected from other Nevada Test Site areas. Surface soil samples from the Area 15 farm contained 238Pu and 239Pu in nanocurie per kilogram concentrations. Hypothetical annual dose estimates to man were calculated on the basis of the daily consumption of 0.5 kilogram of liver or muscle from animals that contained peak radionuclide levels. The highest postulated dose was 0.4 millirems to whole body for 137Cs in muscle obtained from cattle. This dose is about 0.1 percent of the 500 millirems per year radiation protection guide for individuals in the general population. All other postulated doses for consumption of tissues containing other radionuclides were less than 0.1 percent of the standard

  4. Animal investigation program, 1981 annual report: Nevada Test Site and vicinity

    International Nuclear Information System (INIS)

    Data are presented from the radioanalysis of tissues, collected from animals that resided on or near the Nevada Test Site (NTS). Other than naturally occurring potassium-40, cesium-137 was the only gamma-emitting radionuclide frequently detected and was within a narrow range of activity. For example, 12 of 14 cattle muscle samples contained 15 to 65 pCi of cesium-137 per kilogram. Strontium-90 and plutonium-238 or -239 tissue concentrations were similar to those of recent years. Nanocurie levels of tritium were found in tissue from two deer that drank contaminated water draining from the tunnel test areas. Annual dose estimates to man were calculated based on the daily consumption of 0.5 kg of tissue with peak radionuclide levels. The highest postulated dose was 45 millirems to the whole body from ingestion of deer muscle that drank from the tritium contaminated waters. This dose is about 9% of the radiation protection guide. Movement of deer on the NTS is discussed. In general, deer from Pahute Mesa winter in the Timber Mt. area with some movement off the NTS, while deer from Rainier Mesa winter in the Shoshone Mt. area. The sudden death of an offsite goat kid was investigated and death was attributed to enterotoxemia. No gross or microscopic lesions in necropsied animals were found that could be attributed to the effect of ionizing radiation

  5. ANIMAL INVESTIGATION PROGRAM, 1981 ANNUAL REPORT: NEVADA TEST SITE AND VICINITY

    Science.gov (United States)

    Data are presented from the radioanalysis of tissues, collected from animals that resided on or near the Nevada Test Site (NTS). Other than naturally occurring potassium-40, cesium-137 was the only gamma-emitting radionuclide frequently detected and was within a narrow range of a...

  6. ANIMAL INVESTIGATION PROGRAM 1979 ANNUAL REPORT: NEVADA TEST SITE AND VICINITY

    Science.gov (United States)

    Data are presented from the radioanalyses of tissues collected from animals that resided on or near the Nevada Test Site (NTS). Gamma-emitting radionuclides were detected infrequently. Strontium-90 concentrations in bones were lower than those of recent years. Tritium and plutoni...

  7. Animal Investigation Program 1976 annual report: Nevada test site and vicinity

    International Nuclear Information System (INIS)

    Data are presented from the radioanalysis of tissues collected from cattle and mule deer, desert bighorn sheep, feral horses, and other wildlife that resided on or near the Nevada Test Site during 1976. Other than the naturally occurring potassium-40, gamma-emitting radionuclides were detected infrequently with the exception of 131I in animal thyroid samples collected after September 25 (the date of a Chinese nuclear test). Strontium-90 concentrations in bones from deer, cattle, and desert bighorn sheep continued the downward trend of recent years. Tritium concentrations were generally within ambient limits with the exception of animals exposed to sources of contamination; e.g., Sedan Crater, drainage ponds from Area 12 tunnels, etc. Analysis of actinide in tissues was emphasized during 1976. Graphs illustrate the 239P levels in lungs, livers, and femurs from Nevada Test Site beef cattle for the years 1971 through 1976. Femur and lung residue data are nearly identical for each year with liver concentrations being a factor of 2 or 3 lower. Hypothetical dose estimates to man were calculated on the basis of the daily consumption of 0.5 kilogram of liver or muscle from animals that contained peak actinide levels. The highest postulated dose was 11 millirem from tritium from tissues for a mule deer. This dose is about 2% of the 500 millirems/year guide for radiation doses to an individual in the general public. All other postulated doses for consumption of the tissue containing other radionuclides are less than 0.1% of this guide. The food habits of desert bighorn sheep were discussed according to the geographic locations of the animals at time of collection. Grasses made up approximately 60% of the diet at all locations, with shrubs content approaching 30%, and the remainder consisting of various forbs. The movement of 13 mule deer fitted with collars containing a radiotransmitter unit was monitored on a weekly basis

  8. Animal Investigation Program (AIP), A.I.P. summary report on and around the Nevada Test Site from 1982--1995

    Energy Technology Data Exchange (ETDEWEB)

    Giles, K.R.

    1997-04-01

    This report describes the Animal Investigation Program conducted from 1982--1995 by the Environmental Protection Agency`s (EPA`s), Radiation and Indoor Environments National Laboratory (R and IE), formerly Radiation Sciences Laboratory-Las Vegas. This laboratory operates an environmental radiation monitoring program in the region surrounding the Nevada Test Site. The surveillance program was designed to measure levels and trends of radionuclides in animals on and around the Nevada Test Site to ascertain whether world-wide fallout, current radiation levels, and associated doses, to the general public were in compliance with existing radiation protection standards. The surveillance program additionally had the responsibility to take action to protect the health and well-being of the public in the event of any accidental release of radioactive contaminants. Comparison of the measurements and sample analysis results indicated that no significant amounts of biological radionuclides had been detected in the near offsite areas or on the NTS, except in animals drinking water that drains from tunnels in Area 12.

  9. Animal Investigation Program (AIP), A.I.P. summary report on and around the Nevada Test Site from 1982--1995

    International Nuclear Information System (INIS)

    This report describes the Animal Investigation Program conducted from 1982--1995 by the Environmental Protection Agency's (EPA's), Radiation and Indoor Environments National Laboratory (R and IE), formerly Radiation Sciences Laboratory-Las Vegas. This laboratory operates an environmental radiation monitoring program in the region surrounding the Nevada Test Site. The surveillance program was designed to measure levels and trends of radionuclides in animals on and around the Nevada Test Site to ascertain whether world-wide fallout, current radiation levels, and associated doses, to the general public were in compliance with existing radiation protection standards. The surveillance program additionally had the responsibility to take action to protect the health and well-being of the public in the event of any accidental release of radioactive contaminants. Comparison of the measurements and sample analysis results indicated that no significant amounts of biological radionuclides had been detected in the near offsite areas or on the NTS, except in animals drinking water that drains from tunnels in Area 12

  10. Animal Investigation Program 1976 annual report: Nevada test site and vicinity. [Radioanalysis of tissues from animals residing on or near NTS in 1976

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D.D.; Giles, K.R.; Bernhardt, D.E.; Brown, K.W.

    1978-11-01

    Data are presented from the radioanalysis of tissues collected from cattle and mule deer, desert bighorn sheep, feral horses, and other wildlife that resided on or near the Nevada Test Site during 1976. Other than the naturally occurring potassium-40, gamma-emitting radionuclides were detected infrequently with the exception of /sup 131/I in animal thyroid samples collected after September 25 (the date of a Chinese nuclear test). Strontium-90 concentrations in bones from deer, cattle, and desert bighorn sheep continued the downward trend of recent years. Tritium concentrations were generally within ambient limits with the exception of animals exposed to sources of contamination; e.g., Sedan Crater, drainage ponds from Area 12 tunnels, etc. Analysis of actinide in tissues was emphasized during 1976. Graphs illustrate the /sup 239/P levels in lungs, livers, and femurs from Nevada Test Site beef cattle for the years 1971 through 1976. Femur and lung residue data are nearly identical for each year with liver concentrations being a factor of 2 or 3 lower. Hypothetical dose estimates to man were calculated on the basis of the daily consumption of 0.5 kilogram of liver or muscle from animals that contained peak actinide levels. The highest postulated dose was 11 millirem from tritium from tissues for a mule deer. This dose is about 2% of the 500 millirems/year guide for radiation doses to an individual in the general public. All other postulated doses for consumption of the tissue containing other radionuclides are less than 0.1% of this guide. The food habits of desert bighorn sheep were discussed according to the geographic locations of the animals at time of collection. Grasses made up approximately 60% of the diet at all locations, with shrubs content approaching 30%, and the remainder consisting of various forbs. The movement of 13 mule deer fitted with collars containing a radiotransmitter unit was monitored on a weekly basis.

  11. Investigating Elementary Teachers' Conceptions of Animal Classification

    Science.gov (United States)

    Burgoon, Jacob N.; Duran, Emilio

    2012-01-01

    Numerous studies have been conducted regarding alternative conceptions about animal diversity and classification, many of which have used a cross-age approach to investigate how students' conceptions change over time. None of these studies, however, have investigated teachers' conceptions of animal classification. This study was intended to…

  12. Two Programs Educating the Public in Animal Learning and Behavior

    OpenAIRE

    Estep, Daniel Q.

    2002-01-01

    Two educational programs have been developed that teach basic principles of animal learning and behavior and how they can be used in day to day interactions with companion animals. The first program educates violators of animal control laws about animal learning and cat and dog behavior to help them resolve their problems with their animals and avoid future animal control violations. The second educates home service providers concerning basic principles of animal communication, dog behavior, ...

  13. Clinical investigation program, fiscal year 1991

    Science.gov (United States)

    Schydlower, Manuel

    1992-02-01

    Subject report identifies the research activities conducted at William Beaumont Army Medical Center by investigators who had protocols approved by the Clinical Investigation Committee, the Institutional Review Board, and the Animal Use Committee. This report includes all protocols registered with the Department of Clinical Investigation during FY 1991. All known presentations and publications are also included. The research protocols described were conducted under the provisions of AR 40-38 (Clinical Investigation Program); AR 40-7 (Use of Investigational Drugs in Humans and the Use of Schedule 1 Controlled Substances); AR 70-25 (Usle of Volunteers as Subjects of Research); HSC 40-32 (Management of Clinical Investigation Protocols and Reports); and AR 70-18 (The Use of Animals in DOS programs).

  14. Animal models for investigating chronic pancreatitis

    Directory of Open Access Journals (Sweden)

    Aghdassi Alexander A

    2011-12-01

    Full Text Available Abstract Chronic pancreatitis is defined as a continuous or recurrent inflammatory disease of the pancreas characterized by progressive and irreversible morphological changes. It typically causes pain and permanent impairment of pancreatic function. In chronic pancreatitis areas of focal necrosis are followed by perilobular and intralobular fibrosis of the parenchyma, by stone formation in the pancreatic duct, calcifications in the parenchyma as well as the formation of pseudocysts. Late in the course of the disease a progressive loss of endocrine and exocrine function occurs. Despite advances in understanding the pathogenesis no causal treatment for chronic pancreatitis is presently available. Thus, there is a need for well characterized animal models for further investigations that allow translation to the human situation. This review summarizes existing experimental models and distinguishes them according to the type of pathological stimulus used for induction of pancreatitis. There is a special focus on pancreatic duct ligation, repetitive overstimulation with caerulein and chronic alcohol feeding. Secondly, attention is drawn to genetic models that have recently been generated and which mimic features of chronic pancreatitis in man. Each technique will be supplemented with data on the pathophysiological background of the model and their limitations will be discussed.

  15. Animal models for investigating chronic pancreatitis.

    Science.gov (United States)

    Aghdassi, Alexander A; Mayerle, Julia; Christochowitz, Sandra; Weiss, Frank U; Sendler, Matthias; Lerch, Markus M

    2011-01-01

    Chronic pancreatitis is defined as a continuous or recurrent inflammatory disease of the pancreas characterized by progressive and irreversible morphological changes. It typically causes pain and permanent impairment of pancreatic function. In chronic pancreatitis areas of focal necrosis are followed by perilobular and intralobular fibrosis of the parenchyma, by stone formation in the pancreatic duct, calcifications in the parenchyma as well as the formation of pseudocysts. Late in the course of the disease a progressive loss of endocrine and exocrine function occurs. Despite advances in understanding the pathogenesis no causal treatment for chronic pancreatitis is presently available. Thus, there is a need for well characterized animal models for further investigations that allow translation to the human situation. This review summarizes existing experimental models and distinguishes them according to the type of pathological stimulus used for induction of pancreatitis. There is a special focus on pancreatic duct ligation, repetitive overstimulation with caerulein and chronic alcohol feeding. Secondly, attention is drawn to genetic models that have recently been generated and which mimic features of chronic pancreatitis in man. Each technique will be supplemented with data on the pathophysiological background of the model and their limitations will be discussed. PMID:22133269

  16. Roles of Animation Tools in Understanding Programming Concepts

    Science.gov (United States)

    Moreno, Andres; Joy, Mike; Sutinen, Erkki

    2013-01-01

    Computer generated animations are resources used to explain how programs are executed in order to clarify the relevant programming concepts. However, whilst trying to understand new programming concepts it is not clear how and when students benefit from an animation if they are using the tool on their own. To clarify the role of an animation tool…

  17. Investigating Crickets: Observing Animal Exploratory Behavior

    Science.gov (United States)

    Bowen, G. M.

    2008-01-01

    For curriculum content-related reasons, inquiry activities can be difficult in classrooms unless the activities are approached in a manner that makes variations among student group findings understandable in the context of the study. Studies of individual animals and plant reactions to stimuli, such as insect exploratory behavior, allow the…

  18. The GLAST Guest Investigator Program

    Science.gov (United States)

    Band, David L.

    2007-01-01

    We provide an overview of the GLAST Guest Investigator (GI) program, which will support basic research relevant to the GLAST mission in yearly cycles beginning approximately two months after launch. Current details about the GLAST GI program will always be posted on the GLAST Science Support Center (GSSC) website: http://glast.gsfc.nasa.gov/ssc/.

  19. The Significance of Animal Cruelty in Child Protection Investigations

    Science.gov (United States)

    Girardi, Alberta; Pozzulo, Joanna D.

    2012-01-01

    The purpose of this study was to investigate the frequency with which child protection workers (CPWs) in Ontario, Canada, seek information about animal cruelty during investigations of child maltreatment and the extent to which they consider information about animal cruelty when making decisions about whether intervention is required. The CPWs (N…

  20. MICE, a program to track and monitor animals in animal facilities

    Directory of Open Access Journals (Sweden)

    Pognonec Philippe

    2001-03-01

    Full Text Available Abstract Background A growing number of laboratories are using the mouse as a model system in developmental biology as well as in molecular biology. Surprisingly, most of these laboratories do not have reliable computerized systems to track these animals, and the few commercial solutions available are expensive. We thus developed MICE (Mouse Information and Classification Entity, a program aimed at facilitating the monitoring of animals in animal facilities. Results This program consists of a virtual facility in which scientists can perform all the tasks done in the real world (i.e., receiving animals, breeding them, preparing cage labels, etc.. Recording of each animal (birth date, cage number, ID number, tail analysis number, parents, genetic status, genetic background, etc. enables reliable tracking. According to any parameter of interest, animals can then be identified, grouped, sorted, moved, and so forth. Crossings are automatically processed by the program. For example, new genetic backgrounds, generation number, and anticipated due dates are determined. The program also reminds the user when new births are expected and entering newborn animals only requires a few clicks. The genealogy of each animal can be determined in two different ways, one being the visualization of a genealogical tree from which information of ancestors can be retrieved. Conclusion This standalone program, that will be distributed free of charge to academic laboratories requesting a license, represents a new and valuable tool for all animal facility users, and permits simple and reliable tracking and retrieving of animals.

  1. An Approach to Effortless Construction of Program Animations

    Science.gov (United States)

    Velazquez-Iturbide, J. Angel; Pareja-Flores, Cristobal; Urquiza-Fuentes, Jaime

    2008-01-01

    Program animation systems have not been as widely adopted by computer science educators as we might expect from the firm belief that they can help in enhancing computer science education. One of the most notable obstacles to their adoption is the considerable effort that the production of program animations represents for the instructor. We…

  2. Zoonotic disease concerns in animal-assisted therapy and animal visitation programs

    OpenAIRE

    Waltner-Toews, David

    1993-01-01

    A survey was done of 150 systematically selected United States animal care agencies and 74 Canadian humane societies to determine the prevalence of animal assisted therapy (AAT) programs; concerns about, and experience with, zoonotic diseases; and precautions taken to prevent zoonotic disease transmission. Of the 69 US agencies and 49 Canadian societies that reported having AAT programs, 94% used dogs and/or cats in their programs, 28% used rabbits, 15% used “pocket pets” (hamsters, gerbils, ...

  3. Investigating User Experiences Through Animation-based Sketching

    DEFF Research Database (Denmark)

    Vistisen, Peter; Poulsen, Søren Bolvig

    graphics and animation to sketch design ideas into diegetic design solutions. Through a deep-dive into two cases we discuss how animation-based sketching techniques supports the investigation of user experience aspects in design scenarios, and wether the expression is dependent on the visual fidelity or on......This paper discusses the use of animation-based sketching as an approach to explore diegetic designs in the fuzzy front-end ideation of the design process. We present the results from a design workshop with more than 200 participating design students, and 16 companies. The participants used motion...... how animation is applied to support a design narrative anchoring to the context....

  4. Investigating User Experiences Through Animation-based Sketching

    DEFF Research Database (Denmark)

    Vistisen, Peter; Poulsen, Søren Bolvig

    2016-01-01

    This paper discusses the use of animation-based sketching as an approach to explore diegetic designs in the fuzzy front-end ideation of the design process. We present the results from a design workshop with more than 200 partic- ipating design students, and 16 companies. The participants used...... motion graphics and animation to sketch design ideas into diegetic design solutions. Through a deep-dive into two cases studies we discuss how animation-based sketching techniques supported the investigation of user experience aspects in design scenarios, and whether the expression is dependent...... on the visual delity or on how animation is ap- plied to support a design narrative anchoring to the context....

  5. History of the Animal Care Program at Johnson Space Center

    Science.gov (United States)

    Khan-Mayberry, Noreen; Bassett, Stephanie

    2010-01-01

    NASA has a rich history of scientific research that has been conducted throughout our numerous manned spaceflight programs. This scientific research has included animal test subjects participating in various spaceflight missions, including most recently, Space Shuttle mission STS-131. The Animal Care Program at Johnson Space Center (JSC) in Houston, Texas is multi-faceted and unique in scope compared to other centers within the agency. The animal care program at JSC has evolved from strictly research to include a Longhorn facility and the Houston Zoo's Attwater Prairie Chicken refuge, which is used to help repopulate this endangered species. JSC is home to more than 300 species of animals including home of hundreds of white-tailed deer that roam freely throughout the center which pose unique issues in regards to population control and safety of NASA workers, visitors and tourists. We will give a broad overview of our day to day operations, animal research, community outreach and protection of animals at NASA Johnson Space Center.

  6. ANIMAL NUTRITION. PROGRAMMED INSTRUCTION UNITS, ANIMAL NUTRITION, FEED CHARACTERISTICS, VITAMINS, MINERALS. FINAL REPORT NUMBER 12.

    Science.gov (United States)

    LONG, GILBERT A.

    PRINCIPLES AND FACTS NECESSARY FOR EFFECTIVE ANIMAL NUTRITION PRACTICES WERE IDENTIFIED BY EXAMINATION OF RECENT SCIENTIFIC REPORTS. UTILIZING THIS INFORMATION, THE AUTHOR INVOLVED 16 VOCATIONAL AGRICULTURE TEACHERS IN THE DEVELOPMENT AND EXPERIMENTAL USE OF A UNIT OF PROGRAMED LEARNING MATERIALS. INSTRUCTIONAL RESULTS WERE NOT AVAILABLE AT THE…

  7. Animal Science Update Programs--The Role of Teacher Educators.

    Science.gov (United States)

    Osborne, Ed; And Others

    1986-01-01

    Agricultural teachers must continually improve their knowledge and skills in animal science. Teacher educators can play a significant role in this process through the following channels: summer courses, teleconferencing, workshops, summer internships, technical update programs, field days, curriculum materials development and dissemination, and…

  8. Investigating the influence of military actions on animal genome

    International Nuclear Information System (INIS)

    Contemporary world is still faced with misunderstandings between countries and nations that are solved in militant way. Using war a way of solving the problems, brings universal misfortune and deepens injustice. Applying modern arms destroys environment and leaves harmful consequences on contemporary and future world. Of course, the most dangerous influence is manifested on changes in genetic material of human beings. The aim of the investigation was to discover if there were changes in genome of the animals present in the area where the refinery in Novi Sad was bombed. By the means of random sampling we chose 60 cows and 30 pigs from the area where air, water and food was contaminated with a considerate quantity of harmful matters that could be genotoxic. By sterile procedure according to modified Moorhead's method lymphocytes were cultivated, than the technique of G-banding was used (Seobright et al. 1971) According to the International Standards for Karyotyping of Domestic Animals (ISCNDA 1990) the chromosomes were analyzed. In all the investigation 3 cows with numerical and structural changes type aneuploidy and break on chromatids in q-arm were discovered. Analyzing the genome in all the pigs, 2 animals with structural changes of chromosome type ring, deletion and break on q-arm (reciprocal translocation) were discovered. According to the percentage of the changes on 100 examined metaphases, it was discovered that the changes in genetic material appeared 'de novo' and that there are no constitutional changes in karyotype. Out of 90 animals, 5 with chromosome aberration were discovered, which makes 5.5 %. This shows that the changes in genetic material are a consequence of genotoxic agents

  9. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs.

    Science.gov (United States)

    Verrinder, Joy M; Ostini, Remo; Phillips, Clive J C

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was compared with that of students in non-animal related disciplines of human medicine and arts. All students (n = 531) completed a moral reasoning test, the VetDIT, with animal and human scenarios. When compared with reasoning on human ethics issues, the combined group of students evaluating animal ethics issues showed higher levels of Universal Principles reasoning, lower levels of Personal Interest reasoning and similar levels of Maintaining Norms reasoning. Arts students showed more personal interest reasoning than students in most animal-related programs on both animal and human ethics issues, and less norms-based reasoning on animal ethics issues. Medical students showed more norms-based reasoning on animal ethics issues than all of the animal-related groups. There were no differences in principled reasoning on animal ethics issues between program groups. This has implications for animal-related professions and education programs showing that students' preference for principled reasoning on animal ethics issues is not unique to animal-related disciplines, and highlighting the need to develop student (and professional) capacity to apply principled reasoning to address ethics issues in animal industries to reduce the risk of moral distress.

  10. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs.

    Science.gov (United States)

    Verrinder, Joy M; Ostini, Remo; Phillips, Clive J C

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was compared with that of students in non-animal related disciplines of human medicine and arts. All students (n = 531) completed a moral reasoning test, the VetDIT, with animal and human scenarios. When compared with reasoning on human ethics issues, the combined group of students evaluating animal ethics issues showed higher levels of Universal Principles reasoning, lower levels of Personal Interest reasoning and similar levels of Maintaining Norms reasoning. Arts students showed more personal interest reasoning than students in most animal-related programs on both animal and human ethics issues, and less norms-based reasoning on animal ethics issues. Medical students showed more norms-based reasoning on animal ethics issues than all of the animal-related groups. There were no differences in principled reasoning on animal ethics issues between program groups. This has implications for animal-related professions and education programs showing that students' preference for principled reasoning on animal ethics issues is not unique to animal-related disciplines, and highlighting the need to develop student (and professional) capacity to apply principled reasoning to address ethics issues in animal industries to reduce the risk of moral distress. PMID:26934582

  11. Investigating animal health effects of sour gas acid forming emissions

    International Nuclear Information System (INIS)

    The effects of sour gas well blowout emissions on livestock are reviewed. Guidelines for safe drilling operations in hydrogen sulfide environments, general hazards and characteristics of hydrogen sulfide, and guidelines for field investigation into the effects of sour gas and acid emissions on livestock are discussed. A case history involving the Ross No. 2 gas well blowout of July 1985 in Rankin County, Mississippi is presented. The blowout lasted for 72 days, and at peak discharge the 500 ppM radius was ca 3.5 miles. A cattle embryo transplant operation located one half mile from the well was affected by the blowout. Examination by a local veterinarian of the cattle demonstrated eye irritation, epiphora, nasal discharge and coughing. After one and a half months of exposure, most animals showed clinical signs of a severe dry hacking cough, epiphora, dry rales over the thoracic inlet, and a bronchial popping sound over the lateral thorax. All animals had eye irritation. Of 55 animals showing signs of respiratory distress and eye irritations, 15 were still clinically ill in May of 1986. 7 refs., 1 tab

  12. Creative or created: using anecdotes to investigate animal cognition.

    Science.gov (United States)

    Bates, Lucy A; Byrne, Richard W

    2007-05-01

    In non-human animals, creative behaviour occurs spontaneously only at low frequencies, so is typically missed by standardised observational methods. Experimental approaches have tended to rely overly on paradigms from child development or adult human cognition, which may be inappropriate for species that inhabit very different perceptual worlds and possess quite different motor capacities than humans. The analysis of anecdotes offers a solution to this impasse, provided certain conditions are met. To be reliable, anecdotes must be recorded immediately after observation, and only the records of scientists experienced with the species and the individuals concerned should be used. Even then, interpretation of a single record is always ambiguous, and analysis is feasible only when collation of multiple records shows that a behaviour pattern occurs repeatedly under similar circumstances. This approach has been used successfully to study a number of creative capacities of animals: the distribution, nature and neural correlates of deception across the primate order; the occurrence of teaching in animals; and the neural correlates of several aptitudes--in birds, foraging innovation, and in primates, innovation, social learning and tool-use. Drawing on these approaches, we describe the use of this method to investigate a new problem, the cognition of the African elephant, a species whose sheer size and evolutionary distance from humans renders the conventional methods of comparative psychology of little use. The aim is both to chart the creative cognitive capacities of this species, and to devise appropriate experimental methods to confirm and extend previous findings. PMID:17434411

  13. "Quality Handling" a training program to reduce fear and stress in farm animals

    OpenAIRE

    Boivin, X; Ruis, M.A.W.

    2011-01-01

    Research programs such as the European Welfare Quality® program, have attempted to improve animal welfare by developing training programs for improving stockperson behaviour towards the animals. The authors will illustrate different approches in this paper, with a special focus on the Quality Handling program, a multi-media training for improving animal handling in pigs, laying hens and cattle farming.

  14. Free the animals? Investigating attitudes toward animal testing in Britain and the United States.

    Science.gov (United States)

    Swami, Viren; Furnham, Adrian; Christopher, Andrew N

    2008-06-01

    In this study, 185 British and 143 American undergraduates completed a battery of tests that measured attitudes toward animal testing and various individual difference variables. Attitudes toward animal testing factored into two interpretable factors: general attitudes toward animal testing, and animal welfare and conditions of testing. Overall, there was support for animal testing under the right conditions, although there was also concern for the welfare of animals and the conditions under which testing takes place. There were small but significant national difference on both factors (with Americans more positive about testing and less positive about animal welfare), and a significant sex difference on the first factor (women were more negative about testing). Correlation and regression analyses showed that there were few significant individual difference predictors of both factors. These results are discussed in relation to past and future work on attitudes toward animal testing. PMID:18419591

  15. A Factor-Analytic Investigation of Child Animism

    Science.gov (United States)

    Berzonsky, Michael D.

    1973-01-01

    From a factor analysis of 33 variables on 83 first-grade children an animism factor, involving children's conceptions of life, was identified. Animism was found to be relatively independent of operational thought, Piagetian-type problem solving, and the ability to give causal explanations of physical phenomena. (Author)

  16. An Empirical Investigation into Programming Language Syntax

    Science.gov (United States)

    Stefik, Andreas; Siebert, Susanna

    2013-01-01

    Recent studies in the literature have shown that syntax remains a significant barrier to novice computer science students in the field. While this syntax barrier is known to exist, whether and how it varies across programming languages has not been carefully investigated. For this article, we conducted four empirical studies on programming…

  17. USDA animal genomics program: the view from the chicken coop

    OpenAIRE

    Fulton Janet E

    2009-01-01

    Abstract In 2007, the USDA Animal Genomics Strategic Planning Task Force prepared a Blueprint to direct national needs for future research, education, and extension efforts in agricultural animal genomics. This plan is entitled "Blueprint for USDA Efforts in Agricultural Animal Genomics 2008–2017". The Blueprint is reviewed from the perspective of a molecular biologist working within the poultry breeding industry. The diverse species used in animal agriculture require different tools, resourc...

  18. "Quality Handling" a training program to reduce fear and stress in farm animals

    NARCIS (Netherlands)

    Boivin, X.; Ruis, M.A.W.

    2011-01-01

    Research programs such as the European Welfare Quality® program, have attempted to improve animal welfare by developing training programs for improving stockperson behaviour towards the animals. The authors will illustrate different approches in this paper, with a special focus on the Quality Handli

  19. Alpha-1 Antitrypsin Investigations Using Animal Models of Emphysema.

    Science.gov (United States)

    Ni, Kevin; Serban, Karina A; Batra, Chanan; Petrache, Irina

    2016-08-01

    Animal models of disease help accelerate the translation of basic science discoveries to the bedside, because they permit experimental interrogation of mechanisms at relatively high throughput, while accounting for the complexity of an intact organism. From the groundbreaking observation of emphysema-like alveolar destruction after direct instillation of elastase in the lungs to the more clinically relevant model of airspace enlargement induced by chronic exposure to cigarette smoke, animal models have advanced our understanding of alpha-1 antitrypsin (AAT) function. Experimental in vivo models that, at least in part, replicate clinical human phenotypes facilitate the translation of mechanistic findings into individuals with chronic obstructive pulmonary disease and with AAT deficiency. In addition, unexpected findings of alveolar enlargement in various transgenic mice have led to novel hypotheses of emphysema development. Previous challenges in manipulating the AAT genes in mice can now be overcome with new transgenic approaches that will likely advance our understanding of functions of this essential, lung-protective serine protease inhibitor (serpin). PMID:27564666

  20. Using Ants, Animal Behavior & the Learning Cycle to Investigate Scientific Processes

    Science.gov (United States)

    Ligon, Russell A.; Dolezal, Adam G.; Hicks, Michael R.; Butler, Michael W.; Morehouse, Nathan I.; Ganesh, Tirupalavanam G.

    2014-01-01

    The behavior of animals is an intrinsically fascinating topic for students from a wide array of backgrounds. We describe a learning experience using animal behavior that we created for middle school students as part of a graduate-student outreach program, Graduate Partners in Science Education, at Arizona State University in collaboration with a…

  1. Animals

    International Nuclear Information System (INIS)

    The radionuclides of most concern with respect to contamination of animals after a nuclear accident are radioiodine, radiocaesium and radiostrontium (ICRP 30, 1979). Of the other significant anthropogenic radionuclides likely to be released in most accidents, only small proportions of that ingested will be absorbed in an animals gut, and the main animal products, milk and meat, will not normally be contaminated to a significant extent. Animal products will mostly be contaminated as a result of ingestion of contaminated feed and possibly, but to a much lesser extent, from inhalation (for radioiodine only). Direct external contamination of animals is of little or no consequence in human food production. Radioiodine and radiostrontium are important with respect to contamination of milk; radiocaesium contaminates both milk and meat. The physical and chemical form of a radionuclide can influence its absorption in the animal gut. For example, following the Chernobyl accident radiocaesium incorporated into vegetation by root uptake was more readily absorbed than that associated with the original deposit. The transfer of radiocaesium and radiostrontium to animals will be presented both as transfer coefficients and aggregated transfer coefficients. For most animal meat products, only radiocaesium is important as other radionuclides do not significantly contaminate muscle. Farm animal products are the most important foodstuff determining radiocaesium intake by the average consumer in the Nordic countries. The major potential source of radioiodine and radiostrontium to humans is milk and milk products. Of the different species, the smaller animals have the highest transfer of radiocaesium from fodder to meat and milk. (EG)

  2. The History of the Animal Care Program at NASA Johnson Space Center

    Science.gov (United States)

    Khan-Mayberry, Noreen; Bassett, Stephanie

    2010-01-01

    This slide presentation reviews the work of the Animal Care Program (ACP). Animals have been used early in space exploration to ascertain if it were possible to launch a manned spacecraft. The program is currently involved in many studies that assist in enhancing the scientific knowledge of the effect of space travel. The responsibilities of the ACP are: (1) Organize and supervise animal care operations & activities (research, testing & demonstration). (2) Maintain full accreditation by the International Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) (3) Ensure protocol compliance with IACUC recommendations (4) Training astronauts for in-flight animal experiments (5) Maintain accurate & timely records for all animal research testing approved by JSC IACUC (6) Organize IACUC meetings and assist IACUC members (7) Coordinate IACUC review of the Institutional Program for Humane Care and Use of Animals (every 6 mos)

  3. Exploring Animal-Assisted Programs with Children in School and Therapeutic Contexts

    Science.gov (United States)

    Friesen, Lori

    2010-01-01

    Animal-Assisted programs with children are becoming increasingly popular in school and therapeutic settings. This article provides an overview of the benefits accrued by children as well as the concerns with programs which involve animals, and therapy dogs in particular, in these environments. Research over the past 30 years indicates that therapy…

  4. ADAM: A computer program to simulate selective-breeding schemes for animals

    DEFF Research Database (Denmark)

    Pedersen, L D; Sørensen, A C; Henryon, M;

    2009-01-01

    ADAM is a computer program that models selective breeding schemes for animals using stochastic simulation. The program simulates a population of animals and traces the genetic changes in the population under different selective breeding scenarios. It caters to different population structures...

  5. Animals

    Energy Technology Data Exchange (ETDEWEB)

    Skuterud, L.; Strand, P. [Norwegian Radiation Protection Authority (Norway); Howard, B.J. [Inst. of Terrestrial Ecology (United Kingdom)

    1997-10-01

    The radionuclides of most concern with respect to contamination of animals after a nuclear accident are radioiodine, radiocaesium and radiostrontium (ICRP 30, 1979). Of the other significant anthropogenic radionuclides likely to be released in most accidents, only small proportions of that ingested will be absorbed in an animals gut, and the main animal products, milk and meat, will not normally be contaminated to a significant extent. Animal products will mostly be contaminated as a result of ingestion of contaminated feed and possibly, but to a much lesser extent, from inhalation (for radioiodine only). Direct external contamination of animals is of little or no consequence in human food production. Radioiodine and radiostrontium are important with respect to contamination of milk; radiocaesium contaminates both milk and meat. The physical and chemical form of a radionuclide can influence its absorption in the animal gut. For example, following the Chernobyl accident radiocaesium incorporated into vegetation by root uptake was more readily absorbed than that associated with the original deposit. The transfer of radiocaesium and radiostrontium to animals will be presented both as transfer coefficients and aggregated transfer coefficients. For most animal meat products, only radiocaesium is important as other radionuclides do not significantly contaminate muscle. Farm animal products are the most important foodstuff determining radiocaesium intake by the average consumer in the Nordic countries. The major potential source of radioiodine and radiostrontium to humans is milk and milk products. Of the different species, the smaller animals have the highest transfer of radiocaesium from fodder to meat and milk. (EG). 68 refs.

  6. ISFG: Recommendations regarding the use of non-human (animal) DNA in forensic genetic investigations

    DEFF Research Database (Denmark)

    Linacre, A.; Gusmão, L.; Hecht, W.;

    2010-01-01

    The use of non-human DNA typing in forensic science investigations, and specifically that from animal DNA, is ever increasing. The term animal DNA in this document refers to animal species encountered in a forensic science examination but does not include human DNA. Non-human DNA may either be......: the trade and possession of a species, or products derived from a species, which is contrary to legislation; as evidence where the crime is against a person or property; instances of animal cruelty; or where the animal is the offender. The first instance is addressed by determining the species present......, and the other scenarios can often be addressed by assigning a DNA sample to a particular individual organism. Currently there is little standardization of methodologies used in the forensic analysis of animal DNA or in reporting styles. The recommendations in this document relate specifically to animal DNA...

  7. Animal Antics. Program Guide for the Texas Reading Club, 1987.

    Science.gov (United States)

    Larson, Jeanette

    Developed for the Texas Reading Club, a program sponsored cooperatively by local libraries and the Texas State Library and designed to encourage children and their parents to read and to use the library, this guide is intended to inspire program ideas, including activities, crafts, books, and audiovisuals, appropriate to the Reading Club's 1987…

  8. Investigation and control of anthrax outbreak at the human-animal interface, Bhutan, 2010.

    Science.gov (United States)

    Thapa, Nirmal K; Tenzin; Wangdi, Karma; Dorji, Tshering; Migma; Dorjee, Jambay; Marston, Chung K; Hoffmaster, Alex R

    2014-09-01

    In 2010, we investigated anthrax outbreak in Bhutan. A total of 43 domestic animals died, and cutaneous anthrax developed in 9 persons, and 1 died. All affected persons had contact with the carcasses of infected animals. Comprehensive preparedness and response guidelines are needed to increase public awareness of anthrax in Bhutan.

  9. Animal models for investigating the central control of the mammalian diving response

    Directory of Open Access Journals (Sweden)

    Paul eMcculloch

    2012-05-01

    Full Text Available Pioneering studies by Per Scholander indicated that the diving response consists of reflexly induced apnea, bradycardia and an alteration of blood flow that maintains perfusion of the heart and brain. More recently field physiological studies have shown that many marine animals can adjust cardiorespiratory aspects of their diving response depending upon the behavioral situation. This could suggest that the very labile heart rate during diving is under direct cortical control. However, the final control of ANS functioning resides within the brainstem and not the cortex. Many physiologists regard the brain as a black box where important neuronal functioning occurs, but the complexity of such functioning leaves systematic investigation a daunting task. As a consequence the central control of the diving response has been under-investigated. Thus, to further advance the field of diving physiology by understanding its central neuronal control, it would be first necessary to understand the reflex circuitry that exists within the brainstem of diving animals. To do this will require an appropriate animal model. In this review, two animals, the muskrat and rat, will be offered as animal models to investigate the central aspects of the diving response. Firstly, although these rodents are not marine animals, natural histories indicate that both animals can and do exploit aquatic environments. Secondly, physiological recordings during natural and simulated diving indicate that both animals possess the same basic physiological responses to underwater submersion that occur in marine animals. Thirdly, the size and ease of housing of both animals makes them attractive laboratory research animals. Finally, the enormous amount of scientific literature regarding rodent brainstem autonomic control mechanisms, and the availability of brain atlases, makes these animals ideal choices to study the central control of the mammalian diving response.

  10. Animals

    Institute of Scientific and Technical Information of China (English)

    杨光

    2000-01-01

    The largest animal ever to live on the earth is the blue whale(蓝鲸)It weighs about 80 tons--more than 24 elephants. It is more than 30 metres long. A newborn baby whale weighs as much as a big elephant.

  11. 45 CFR 681.4 - Who investigates program fraud?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Who investigates program fraud? 681.4 Section 681... PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Procedures Leading to Issuance of A Complaint § 681.4 Who investigates program fraud? The Inspector General, or his or her designee, is the investigating...

  12. The influence of conservation breeding programs on animal communication and behaviour – a literary review.

    OpenAIRE

    Danial Rioldi, Emmanuela

    2013-01-01

    Abstract This literary review is focused on how conservation breeding programs may influence an animal’s behaviour and communication and if this may affect reintroduction. The expansion of the human population is an increasing threat to all wild animals and their habitats. Animals are forced to survive in smaller areas and the worst case scenario is extinction. Animals communicate with each other using various types of signals to transmit information about their reproductive status, intentio...

  13. ANIMALS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Mammals(哺乳动物)Mammals are the world's most dominant(最占优势的)animal.They are extremely(非常)diverse(多种多样的)creatures(生物,动物)that include(包括)the biggest ever animal (the blue whale鲸,which eats up to 6 tons every day),the smallest(leaf-nosed bat小蹄蝠) and the laziest(sloth树獭,who spends 80% of their time sleeping).There are over 4,600 kinds of mammals and they live in very different environments(环境)—oceans(海洋),rivers,the jungle(丛林),deserts,and plains(平原).

  14. Animal Models and Bone Histomorphometry: Translational Research for the Human Research Program

    Science.gov (United States)

    Sibonga, Jean D.

    2010-01-01

    This slide presentation reviews the use of animal models to research and inform bone morphology, in particular relating to human research in bone loss as a result of low gravity environments. Reasons for use of animal models as tools for human research programs include: time-efficient, cost-effective, invasive measures, and predictability as some model are predictive for drug effects.

  15. Developing a Comprehensive Animal Care Occupational Health and Safety Program at a Land-Grant Institution.

    Science.gov (United States)

    Goodly, Lyndon J; Jarrell, Vickie L; Miller, Monica A; Banks, Maureen C; Anderson, Thomas J; Branson, Katherine A; Woodward, Robert T; Peper, Randall L; Myers, Sara J

    2016-01-01

    The Public Health Service Policy on the Humane Care and Use of Laboratory Animals and sound ethical practices require institutions to provide safe working environments for personnel working with animals; this mandate is achieved in part by establishing an effective animal care Occupational Health and Safety Program (OHSP). Land-grant institutions often face unique organizational challenges in fulfilling this requirement. For example, responsibilities for providing health and safety programs often have historically been dispersed among many different divisions scattered around the campus. Here we describe how our institutional management personnel overcame organizational structure and cultural obstacles during the formation of a comprehensive campus-wide animal care OHSP. Steps toward establishing the animal care OHSP included assigning overall responsibility, identifying all stakeholders, creating a leadership group, and hiring a fulltime Animal Care OHSP Specialist. A web-based portal was developed, implemented, and refined over the past 7 y and reflected the unique organizational structures of the university and the needs of our research community. Through this web-based portal, hazards are identified, risks are assessed, and training is provided. The animal care OHSP now provides easy mandatory enrollment, supports timely feedback regarding hazards, and affords enrollees the opportunity to participate in voluntary medical surveillance. The future direction and development of the animal care OHSP will be based on the research trends of campus, identification of emerging health and safety hazards, and ongoing evaluation and refinement of the program.

  16. Developing a Comprehensive Animal Care Occupational Health and Safety Program at a Land-Grant Institution.

    Science.gov (United States)

    Goodly, Lyndon J; Jarrell, Vickie L; Miller, Monica A; Banks, Maureen C; Anderson, Thomas J; Branson, Katherine A; Woodward, Robert T; Peper, Randall L; Myers, Sara J

    2016-01-01

    The Public Health Service Policy on the Humane Care and Use of Laboratory Animals and sound ethical practices require institutions to provide safe working environments for personnel working with animals; this mandate is achieved in part by establishing an effective animal care Occupational Health and Safety Program (OHSP). Land-grant institutions often face unique organizational challenges in fulfilling this requirement. For example, responsibilities for providing health and safety programs often have historically been dispersed among many different divisions scattered around the campus. Here we describe how our institutional management personnel overcame organizational structure and cultural obstacles during the formation of a comprehensive campus-wide animal care OHSP. Steps toward establishing the animal care OHSP included assigning overall responsibility, identifying all stakeholders, creating a leadership group, and hiring a fulltime Animal Care OHSP Specialist. A web-based portal was developed, implemented, and refined over the past 7 y and reflected the unique organizational structures of the university and the needs of our research community. Through this web-based portal, hazards are identified, risks are assessed, and training is provided. The animal care OHSP now provides easy mandatory enrollment, supports timely feedback regarding hazards, and affords enrollees the opportunity to participate in voluntary medical surveillance. The future direction and development of the animal care OHSP will be based on the research trends of campus, identification of emerging health and safety hazards, and ongoing evaluation and refinement of the program. PMID:26817980

  17. 45 CFR 2554.7 - Who investigates program fraud?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Who investigates program fraud? 2554.7 Section... COMMUNITY SERVICE PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Procedures Leading to Issuance of A Complaint § 2554.7 Who investigates program fraud? The Inspector General, or his designee, is the...

  18. The extinct animal show: the paleoimagery tradition and computer generated imagery in factual television programs.

    Science.gov (United States)

    Campbell, Vincent

    2009-03-01

    Extinct animals have always been popular subjects for the media, in both fiction, and factual output. In recent years, a distinctive new type of factual television program has emerged in which computer generated imagery is used extensively to bring extinct animals back to life. Such has been the commercial audience success of these programs that they have generated some public and academic debates about their relative status as science, documentary, and entertainment, as well as about their reflection of trends in factual television production, and the aesthetic tensions in the application of new media technologies. Such discussions ignore a crucial contextual feature of computer generated extinct animal programs, namely the established tradition of paleoimagery. This paper examines a selection of extinct animal shows in terms of the dominant frames of the paleoimagery genre. The paper suggests that such an examination has two consequences. First, it allows for a more context-sensitive evaluation of extinct animal programs, acknowledging rather than ignoring relevant representational traditions. Second, it allows for an appraisal and evaluation of public and critical reception of extinct animal programs above and beyond the traditional debates about tensions between science, documentary, entertainment, and public understanding. PMID:19579684

  19. An Experiment on the Short-Term Effects of Engagement and Representation in Program Animation

    Science.gov (United States)

    Nevalainen, Seppo; Sajaniemi, Jorma

    2008-01-01

    When visualization tools utilized in computer programming education have been evaluated empirically, the results have remained controversial. To address this problem, we have developed a model of short-term effects of program animation, and used it in a series of experiments. In the current experiment, we varied visual representation of an…

  20. 5TH BIOTECHNOLOGICAL INVESTIGATIONS OCEAN MARGINS PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    DR. ARTURO MASSOL, PROGRAM CHAIR; DR. ROSA BUXEDA, PROGRAM CO-CHAIR

    2004-01-08

    BI-OMP supports DOE's mission in Climate Change Research. The program provides the fundamental understanding of the linkages between carbon and nitrogen cycles in ocean margins. Researchers are providing a mechanistic understanding of these cycles, using the tools of modern molecular biology. The models that will allow policy makers to determine safe levels of greenhouse gases for the Earth System.

  1. An Investigation of Teaching and Learning Programs in Pharmacy Education.

    Science.gov (United States)

    Strang, Aimee F; Baia, Patricia

    2016-05-25

    Objective. To investigate published, peer-reviewed literature on pharmacy teaching and learning development programs and to synthesize existing data, examine reported efficacy and identify future areas for research. Methods. Medline and ERIC databases were searched for studies on teaching development programs published between 2001 and 2015. Results. Nineteen publications were included, representing 21 programs. Twenty programs were resident teaching programs, one program described faculty development. The majority of programs spanned one year and delivered instruction on teaching methodologies and assessment measures. All except one program included experiential components. Thirteen publications presented outcomes data; most measured satisfaction and self-perceived improvement. Conclusion. Published literature on teacher development in pharmacy is focused more on training residents than on developing faculty members. Although programs are considered important and highly valued by program directors and participants, little data substantiates that these programs improve teaching. Future research could focus on measurement of program outcomes and documentation of teaching development for existing faculty members.

  2. Helping War Veterans with Posttraumatic Stress Disorder: Incarcerated Individuals' Role in Therapeutic Animal Programs.

    Science.gov (United States)

    Furst, Gennifer

    2016-05-01

    A grassroots movement of nonprofit, nongovernmental organizations is creating programs in which incarcerated individuals train rescued shelter dogs as therapeutic canines for Veterans with posttraumatic stress disorder (PTSD). Driven in part by reports of Veterans not receiving adequate treatment for PTSD, the programs are the latest iteration of prison-based animal programs and are founded on the principles of animal therapy and healing powers of animals. The far-reaching and deleterious collateral consequences of PTSD create social and economic burdens on the country; providing beneficial interventions for Veterans is a pressing social problem. Without oversight, a patchwork of agencies has developed that provides Veterans with dogs with varying levels of training and differing abilities. To best serve the needs of Veterans, the programs need regulation and standardized methods of training. [Journal of Psychosocial Nursing and Mental Health Services, 54(5), 49-57.]. PMID:27135894

  3. Investigating the dopaminergic synapse in vivo. II. Molecular imaging studies in small laboratory animals.

    Science.gov (United States)

    Nikolaus, Susanne; Larisch, Rolf; Beu, Markus; Antke, Christina; Kley, Konstantin; Forutan, Farhad; Wirrwar, Andreas; Müller, Hans-Wilhelm

    2007-01-01

    Dopaminergic synaptic function may be assessed either at the presynaptic terminal or at the postsynaptic binding sites using molecular in vivo imaging methods. Apart from the density of binding sites, parameters such as alterations in dopamine synthesis, dopamine storage or dopamine release can be quantified either by application of specific radiotracers or by assessing the competition between the exogenous radioligand and endogenous dopamine. The performance of animal studies allows the induction of specific short-term or long-term synaptic conditions via pharmacological challenges or infliction of neurotoxic lesions. Therefore, small laboratory animals such as rats and mice have become invaluable models for a variety of human disorders. This article gives an overview of those small animal studies which have been performed so far on dopaminergic neurotransmission using in vivo imaging methods, with a special focus on the relevance of findings within the functional entity of the dopaminergic synapse. Taken together, in vivo investigations on animal models of Parkinson's disease showed decreases of dopamine storage, dopamine release and dopamine transporter binding, no alterations of dopamine synthesis and DA release, and either increases or no alterations of D2 receptor binding, while in vivo investigations of animal models of Huntington's disease. showed decreases of DAT and D1 receptor binding. For D2 receptor binding, both decreases and increases have been reported, dependent on the radioligand employed. Substances of abuse, such as alcohol, amphetamine and methylphenidate, led to an increase of dopamine release in striatal regions. This held for the acute application of substances to both healthy animals and animal models of drug abuse. Findings also showed that chronic application of cocaine induced long-term reductions of both D1 and D2 receptor binding, which disappeared after several weeks of withdrawal. Finally, preliminary results yielded the first

  4. Animal Ambassadors . . . 4-H teens learn to lead science program for kids

    OpenAIRE

    Smith, Martin H; Enfield, Richard P.; Meehan, Cheryl L.; Klingborg, Donald J.

    2004-01-01

    To improve science literacy among school-age children in the United States, educators must receive effective training and support, and children must be engaged in science at a young age. Animal Ambassadors is a science-education outreach program of the UC School of Veterinary Medicine, Veterinary Medicine Extension, which focuses on the awareness and understanding of animal-related concepts and emphasizes important critical thinking and life skills. Through a collaboration with UC Cooperative...

  5. Animal foods, protein, calcium and prostate cancer risk: the European Prospective Investigation into Cancer and Nutrition.

    NARCIS (Netherlands)

    Allen, N.E.; Key, T.J.; Appleby, P.N.; Travis, R.C.; Roddam, A.W.; Tjonneland, A.; Johnsen, N.F.; Overvad, K.; Linseisen, J.; Rohrmann, S.; Boeing, H.; Pischon, T.; Bueno-De-Mesquita, H.B.; Kiemeney, L.; Tagliabue, G.; Palli, D.; Vineis, P.; Tumino, R.; Trichopoulou, A.; Kassapa, C.; Trichopoulos, D.; Ardanaz, E.; Larranaga, N.; Tormo, M.J.; Gonzalez, C.A.; Quiros, J.R.; Sanchez, M.J.; Bingham, S.; Khaw, K.T.; Manjer, J.; Berglund, G.; Stattin, P.; Hallmans, G.; Slimani, N.; Ferrari, P.; Rinaldi, S.; Riboli, E.

    2008-01-01

    We examined consumption of animal foods, protein and calcium in relation to risk of prostate cancer among 142 251 men in the European Prospective Investigation into Cancer and Nutrition. Associations were examined using Cox regression, stratified by recruitment centre and adjusted for height, weight

  6. Animal foods, protein, calcium and prostate cancer risk : the European Prospective Investigation into Cancer and Nutrition

    NARCIS (Netherlands)

    Allen, N. E.; Key, T. J.; Appleby, P. N.; Travis, R. C.; Roddam, A. W.; Tjonneland, A.; Johnsen, N. F.; Overvad, K.; Linseisen, J.; Rohrmann, S.; Boeing, H.; Pischon, T.; Bueno-de-Mesquita, H. B.; Kiemeney, L.; Tagliabue, G.; Palli, D.; Vineis, P.; Tumino, R.; Trichopoulou, A.; Kassapa, C.; Trichopoulos, D.; Ardanaz, E.; Larranaga, N.; Tormo, M-J; Gonzalez, C. A.; Quiros, J. R.; Sanchez, M-J; Bingham, S.; Khaw, K-T; Manjer, J.; Berglund, G.; Stattin, P.; Hallmans, G.; Slimani, N.; Ferrari, P.; Rinaldi, S.; Riboli, E.

    2008-01-01

    We examined consumption of animal foods, protein and calcium in relation to risk of prostate cancer among 142 251 men in the European Prospective Investigation into Cancer and Nutrition. Associations were examined using Cox regression, stratified by recruitment centre and adjusted for height, weight

  7. An Investigation of Human-Computer Interaction Approaches Beneficial to Weak Learners in Complex Animation Learning

    Science.gov (United States)

    Yeh, Yu-Fang

    2016-01-01

    Animation is one of the useful contemporary educational technologies in teaching complex subjects. There is a growing interest in proper use of learner-technology interaction to promote learning quality for different groups of learner needs. The purpose of this study is to investigate if an interaction approach supports weak learners, who have…

  8. Establishment of an operating room committee and a training program to improve aseptic techniques for rodent and large animal surgery.

    Science.gov (United States)

    Héon, Hélène; Rousseau, Nathalie; Montgomery, Jane; Beauregard, Gilles; Choiniére, Manon

    2006-11-01

    Investigators of our research facility generally accept the concept of asepsis as an important component of adequate surgical care for animals. However, they experience difficulties putting it into practice, especially in the case of rodents. The reasons for this are inconvenience, cost, and lack of training. To better assist investigators in the implementation of aseptic surgical techniques in their laboratories, we have created an Operating Room (OR) Committee modeled after OR committees found in human hospitals. A reconstructive surgeon, a veterinarian, a research scientist, a nurse involved in the training of OR personnel, interns, graduate students, and an animal health technician were chosen as committee members in light of their OR and animal care expertise. The first task of the OR Committee was to establish institutional guidelines for aseptic surgery, taking into account the costs imposed on research budgets by these procedures. The OR Committee also supports a complete training program in aseptic surgery techniques, which consists of lectures, a training manual, videos, and a practical course. Furthermore, when experimental procedures require specialized equipment, the OR Committee collaborates with researchers to develop strategies to achieve asepsis. This OR Committee and the training program proved to be important tools to promote and improve the quality of animal care during surgery.

  9. 21 CFR 312.160 - Drugs for investigational use in laboratory research animals or in vitro tests.

    Science.gov (United States)

    2010-04-01

    ... research animals or in vitro tests. 312.160 Section 312.160 Food and Drugs FOOD AND DRUG ADMINISTRATION... Drugs for Investigational Use in Laboratory Research Animals or In Vitro Tests § 312.160 Drugs for investigational use in laboratory research animals or in vitro tests. (a) Authorization to ship. (1)(i) A...

  10. Honeywell optical investigations on FLASH program

    Science.gov (United States)

    O'Rourke, Ken; Peterson, Eric; Yount, Larry

    1995-05-01

    The increasing performance and reduction of life cycle cost requirements placed on commercial and military transport aircraft are resulting in more complex, highly integrated aircraft control and management systems. The use of fiber optic data transmission media can make significant contributions in achieving these performance and cost goals. The Honeywell portion of Task 2A on the Fly-by-Light Advanced System Hardware (FLASH) program is evaluating a Primary Flight Control System (PFCS) using pilot and copilot inputs from Active Hand Controllers (AHC) which are optically linked to the primary flight Control Computers (PFCC). Customer involvement is an important element of the Task 2A activity. Establishing customer requirements and perspectives on productization of systems developed under FLASH are key to future product success. The Honeywell elements of the PFCS demonstrator provide a command path that is optically interfaced from crew inputs to commands of distributed, smart actuation subsystems commands. Optical communication architectures are implemented using several protocols including the new AS-1773A 20 Mbps data bus standard. The interconnecting fiber optic cable plant is provided by our Task 1A teammate McDonnell Douglas Aerospace (West). Fiber optic cable plant fabrication uses processed, tools and materials reflecting necessary advances in manufacturing required to make fly-by-light avionics systems marketable.

  11. 13 CFR 142.7 - Who investigates program fraud?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Who investigates program fraud? 142.7 Section 142.7 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION PROGRAM FRAUD CIVIL... fraud? The Inspector General, or his designee, is responsible for investigating allegations that a...

  12. Pavlovian conditioning of immune function: animal investigation and the challenge of human application.

    Science.gov (United States)

    Exton, M S; von Auer, A K; Buske-Kirschbaum, A; Stockhorst, U; Göbel, U; Schedlowski, M

    2000-06-01

    Pavlovian conditioning of immune functions provided early impetus to the rapidly expanding knowledge of bi-directional communication among the immune, endocrine, and central nervous systems. Since these early investigations, the phenomenology of this response has been well characterized. However the neural mechanisms and biological relevance of conditioned immunomodulation remain unclear. To this end, we present here data from our laboratories that have: (1) revealed some of the neural mechanisms and biological relevance of an animal model of conditioned immunomodulation; (2) demonstrated the conditionability and potential mechanisms of conditioned immune responses in healthy humans, and (3) investigated conditioned immunomodulation in a clinical sample. Together, these data demonstrate that animal models provide a basis for investigating mechanisms whereby conditioned changes in immune function may modulate health status in a clinical realm.

  13. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs

    OpenAIRE

    Verrinder, Joy M.; Remo Ostini; Clive J C Phillips

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was co...

  14. Adulthood Animal Abuse among Women Court-Referred to Batterer Intervention Programs

    OpenAIRE

    Febres, Jeniimarie; Shorey, Ryan C.; Brasfield, Hope; Zucosky, Heather C.; Ninnemann, Andrew; Elmquist, Joanna; Bucossi, Meggan M.; Andersen, Shawna M.; Schonbrun, Yael C.; Stuart, Gregory L.

    2012-01-01

    The substantial increase in the enrollment of women in batterer intervention programs (BIPs) over the past thirty years has greatly outpaced research on women who perpetrate intimate partner violence (IPV). As a result, it is unknown whether existing programs, which were originally designed to treat male perpetrators, are effective at preventing recidivism among women. Recent research shows that men who perpetrate IPV may also aggress against non-intimate partners, children, and animals, and ...

  15. Use of Animal Models to Investigate Major Allergens Associated with Food Allergy

    Directory of Open Access Journals (Sweden)

    Jenna L. Van Gramberg

    2013-01-01

    Full Text Available Food allergy is an emerging epidemic that affects all age groups, with the highest prevalence rates being reported amongst Western countries such as the United States (US, United Kingdom (UK, and Australia. The development of animal models to test various food allergies has been beneficial in allowing more rapid and extensive investigations into the mechanisms involved in the allergic pathway, such as predicting possible triggers as well as the testing of novel treatments for food allergy. Traditionally, small animal models have been used to characterise immunological pathways, providing the foundation for the development of numerous allergy models. Larger animals also merit consideration as models for food allergy as they are thought to more closely reflect the human allergic state due to their physiology and outbred nature. This paper will discuss the use of animal models for the investigation of the major food allergens; cow's milk, hen's egg, and peanut/other tree nuts, highlight the distinguishing features of each of these models, and provide an overview of how the results from these trials have improved our understanding of these specific allergens and food allergy in general.

  16. Venomous Animals and Their Victims: A Program for Sophomore Medical Students

    Science.gov (United States)

    Daly, James J.

    1977-01-01

    In the University of Arkansas for Medical Sciences program, lectures are given on the recognition and general biology of dangerous reptiles and anthropods, the nature of animal venoms, immunological aspects of envenomation, and treatment of bites and stings. Both first-aid and clinical management are included. (Author/LBH)

  17. An on-farm investigation of beef suckler herds using an animal welfare index (AWI

    Directory of Open Access Journals (Sweden)

    Veissier Isabelle

    2010-12-01

    Full Text Available Abstract Background Beef suckler farms (194 farms throughout 13 counties were assessed once with housed cattle and once with cattle at grass using an animal welfare index (AWI. Twenty-three of the 194 farms were revisited a year later and re-evaluated using the AWI and the Tier-Gerechtheits-Index 35L/2000 (TGI35L/2000. Thirty-three indicators were collected in five categories: locomotion (5 indicators; social interactions (between animals (7, flooring (5, environment (7 and Stockpersonship (9. Three indicators relating to the size of the farm were also collected. Improving animal welfare is an increasingly important aspect of livestock production systems predominantly due to increased consumer concern about the source of animal products. The objectives were (i to evaluate animal welfare of Irish beef suckler herds using an animal welfare index (AWI, (ii to examine correlations between parameters, how they influence the AWI and investigate the applicability of the parameters used, (iii to investigate the impact of the activity of the farmer (full-time or part-time, the interest of the farmer and the number of animals on the AWI. Results The mean AWI was 65% and ranged from 54% to 83%. The grazing period represented 16.5% of the total points of the AWI. Seventy percent of the farms were rated as "Very Good" or "Excellent". There was no difference (P > 0.05 in AWI between full-time and part-time farmers. Part-time farmers had greater (P = 0.01 "social interactions": calving (P = 0.03 and weaning (P Conclusion The AWI was easily applicable for an on-farm evaluation of welfare. The Stockpersonship was an important factor in determining the AWI (11% of the total variation more specifically, the interest of the farmer. Part and full-time farming did not differ (P > 0.05 in AWI scores. This method could, with further development, be used in countries with both intensive and/or extensive production systems and would require substantially less resources

  18. Use of radiations and radioisotopes for investigating problems connected with parasitic diseases of animals in India

    International Nuclear Information System (INIS)

    The status of the present knowledge regarding the use of isotopes and radiations for studies of animal parasitic diseases in India is reviewed. The concepts in immunology of metazoan parasites with relevance to vaccination have been discussed. A brief review of radiation attenuated vaccines against certain economically important species of helminth parasites and the use of radioisotopes for pathophysiological investigations and for the study of anthelmintic activity is given. (auth.)

  19. INVESTIGATION ON THE ACUTE AND SUBACUTE TOXICITY OFALHAGI GRAECORUM IN EXPERIMENTAL ANIMALS

    Directory of Open Access Journals (Sweden)

    Huda Gargum

    2013-08-01

    Full Text Available Little is known about the acute and subacute toxicity of Alhagi Graecorum (Camel Thorn in mice. The aim of this study is to investigate the acute toxicity (LD50 and sub acute toxicity of camel thorn in mice. For determination of LD50, mice weighing 25-30 g were divided into nine groups each of 6 animals and received 130, 330, 660, 1300, 2600, 4200, 5000, 5900 and 6900 mg/kg orally of camel thorn water extract respectively. The sign and symptoms of toxicity and the number of died animals in each group were registered and the LD50 was calculated.Another group of Male albino mice weighed 25-30 g were divided into control and different treated group each of 6 mice and placed in the metabolism cages that allowed daily measurement of food and water consumption. The control received normal saline whereas the other groups received 130, 660, 1300 mg/kg (i.p, daily of camel thorn extract (CTErespectively, for two weeks.. The animals were weighed daily for any sign of reduction or gain of body weight. The food and water consumption were daily calculated. At the end of this experiment, the mice were killed and blood was collected and used for the determination of glucose and the serum creatinine,urea, aspartate, aminotransferase, (AST and alanine aminotransferase (ALT levels.The liver of the animals were removed,fixed in 10%formaline for histopathological investigation. The LD50 was equal to 5400mg/kg.Results of sub acute toxicity studies revealed that no significant weight reduction were observed in treated groups as compared to control, however the food consumption was significantly increased in the mice received 660mg/kg of CTE . Also the water consumption was significantly decreased in the animal receiving 1300mg/kg of CTE.

  20. Programs to improve production and consumption of animal source foods and malnutrition in Vietnam.

    Science.gov (United States)

    Hop, Le Thi

    2003-11-01

    The objective of this paper is to review programs to improve production of animal source foods in Vietnam, emphasizing the VAC ecosystem and trends in undernutrition during past decades. The food consumption surveys of the Vietnamese population in 1985 showed that food intake was inadequate, especially animal protein. Most protein came from rice; the consumption of meats, beans and fish was negligible. During the last 10 y, much attention was paid to improving the health and nutritional status of the Vietnamese people. Many programs were implemented in Vietnam to improve the food intake and nutritional status of the people, and especially the intake of animal source foods. The VAC system is a traditional type of farming for Vietnamese people. The aim of VAC is to provide diversified agricultural products to meet the complex nutritional demands of man. Based on the scientific fundamentals of VAC, many different models of VAC have been developed at a national level. The intervention programs to improve production and consumption of animal source foods, and the VAC ecosystem in Vietnam during the last decade have been successful. The population's dietary intakes have clearly improved in terms of both quality and quantity. The consumption of staple foods in 2000, including meats, fish, fats and oils, and ripe fruits was much higher compared to 1987. The prevalence of undernutrition in children <5 y old, and of chronic energy deficiency (CED) in women of reproductive age, has been remarkably reduced.

  1. Comparative investigations on the biokinetics of colloidal thorium, zirconium, and hafnium dioxides in animals

    International Nuclear Information System (INIS)

    The aim of the investigations is to establish biophysical data as a basis for dose calculations of realized projected long-term animal experiments devoted to the problem radiation and nonradiation effect of Thorotrast. For this purpose a Thorotrast-equivalent thorium dioxide aquasol as well as dextrin-stabilized aquasols of zirconium and hafnium dioxides (Zirconotrast, Hafnorast) of our own production have been injected intravascularly into rats. The animals subdivided in four subgroups have been administered 60 to 600 μl of any colloid per rat. Four subgroups were sacrificed at different times between 1 and 100 days after injection. The whole-body kinetics of Thorotrast and Hafnotrast have been studied by single whole-body counting of altogether 10 animals during the total time of exposure. Both the distribution of the colloids and the activity ratios between 232Th and daughters have been determined. Supplementary to these investigations studies were performed on the Thorotrast kinetics in mice and in one dog

  2. An investigation of the challenges in reconstructing PET images of a freely moving animal

    International Nuclear Information System (INIS)

    Imaging the brain of a freely moving small animal using positron emission tomography (PET) while simultaneously observing its behaviour is an important goal for neuroscience. While we have successfully demonstrated the use of line-of-response (LOR) rebinning to correct the head motion of confined animals, a large proportion of events may need to be discarded because they either 'miss' the detector array after transformation or fall out of the acceptance range of a sinogram. The proportion of events that would have been measured had motion not occurred, so-called 'lost events', is expected to be even larger for freely moving animals. Moreover, the data acquisition in the case of a freely moving animal is further complicated by a complex attenuation field. The aims of this study were (a) to characterise the severity of 'lost events' problem for the freely moving animal scenario, and (b) to investigate the relative impact of attenuation correction errors on quantitative accuracy of reconstructed images. A phantom study was performed to simulate the uncorrelated motion of a target and non-target source volume. A small animal PET scanner was used to acquire list-mode data for different sets of phantom positions. The list-mode data were processed using the standard LOR rebinning approach, and multiple frame variants of this designed to reduce discarded events. We found that LOR rebinning caused up to 86 % 'lost events', and artifacts that we attribute to incomplete projections, when applied to a freely moving target. This fraction was reduced by up to 18 % using the variant approaches, resulting in slightly reduced image artifacts. The effect of the non-target compartment on attenuation correction of the target volume was surprisingly small. However, for certain poses where the target and non-target volumes are aligned transaxially in the field-of-view, the attenuation problem becomes more complex and sophisticated correction methods will be required. We conclude that

  3. 40 CFR 122.23 - Concentrated animal feeding operations (applicable to State NPDES programs, see § 123.25).

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Concentrated animal feeding operations... Concentrated animal feeding operations (applicable to State NPDES programs, see § 123.25). (a) Scope. Concentrated animal feeding operations (CAFOs), as defined in paragraph (b) of this section or designated...

  4. 40 CFR 122.24 - Concentrated aquatic animal production facilities (applicable to State NPDES programs, see § 123...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Concentrated aquatic animal production... NATIONAL POLLUTANT DISCHARGE ELIMINATION SYSTEM Permit Application and Special NPDES Program Requirements § 122.24 Concentrated aquatic animal production facilities (applicable to State NPDES programs,...

  5. Animal Use and Lessons Learned in the U.S. High Production Volume Chemicals Challenge Program

    OpenAIRE

    Bishop, Patricia L.; Manuppello, Joseph R.; Willett, Catherine E.; Sandler, Jessica T.

    2012-01-01

    Background: Launched by the U.S. Environmental Protection Agency (EPA) in 1998, the High Production Volume (HPV) Challenge Program was developed to address the perceived gap in basic hazard information for the 2,800 chemicals produced or imported into the United States in quantities of ≥ 1 million pounds per year. Health and environmental effects data obtained from either existing information or through new vertebrate animal testing were voluntarily submitted by chemical companies (sponsors) ...

  6. Investigations of 90 SR activity concentrations in animal bones in Croatia

    Energy Technology Data Exchange (ETDEWEB)

    Maracic, M.; Franic, Z.; Marovic, G. [Institute for Medical Research and Occupational Health, Zagreb (Croatia)

    2006-07-01

    The paper describes investigations of 90 Sr activity concentrations in long bones of some domestic animals (cows, pigs and lambs) collected over the last ten years in the Republic of Croatia. These investigations are a part of an extended and still ongoing monitoring programme of radioactive contamination of human environment in Croatia. Bone is a critical organ for the accumulation of many radionuclides, including 90 Sr, a highly toxic radionuclide, similar to calcium in its chemicalaviour and metabolic processes. It has been found that the 90 Sr activity concentrations in bones differ between respective animal species, the highest activity concentrations being found in lamb bones. As the decrease of activity concentrations can be generally described by the exponential function, by fitting the measured data to the theoretical curve was estimated the ecological half-life of 90 Sr in bones of respective species. In addition was investigated the relation between 90 Sr activity concentrations in bones and fallout. The transient increases and decreases in 90 Sr activity concentrations in bones can be partially explained by a variety of environmental physical factors that naturally fluctuate. (authors)

  7. Structural Reforms, IMF Programs and Capacity Building; An Empirical Investigation

    OpenAIRE

    Rabah Arezki; Marc Quintyn; Frederik G Toscani

    2012-01-01

    This paper investigates the role that International Monetary Fund (IMF) programs and capacity building play in fostering structural reforms. To do so, we exploit two novel datasets on IMF capacity building and structural reforms available for over one hundred IMF member countries over the period 1980 - 2010. The main results are threefold. First, there is a general association between IMF programs and structural reforms but this relationship is not very robust. Second, IMF training leads to a...

  8. A unique in vivo approach for investigating antimicrobial materials utilizing fistulated animals

    Science.gov (United States)

    Berean, Kyle J.; Adetutu, Eric M.; Zhen Ou, Jian; Nour, Majid; Nguyen, Emily P.; Paull, David; Mcleod, Jess; Ramanathan, Rajesh; Bansal, Vipul; Latham, Kay; Bishop-Hurley, Greg J.; McSweeney, Chris; Ball, Andrew S.; Kalantar-zadeh, Kourosh

    2015-01-01

    Unique in vivo tests were conducted through the use of a fistulated ruminant, providing an ideal environment with a diverse and vibrant microbial community. Utilizing such a procedure can be especially invaluable for investigating the performance of antimicrobial materials related to human and animal related infections. In this pilot study, it is shown that the rumen of a fistulated animal provides an excellent live laboratory for assessing the properties of antimicrobial materials. We investigate microbial colonization onto model nanocomposites based on silver (Ag) nanoparticles at different concentrations into polydimethylsiloxane (PDMS). With implantable devices posing a major risk for hospital-acquired infections, the present study provides a viable solution to understand microbial colonization with the potential to reduce the incidence of infection through the introduction of Ag nanoparticles at the optimum concentrations. In vitro measurements were also conducted to show the validity of the approach. An optimal loading of 0.25 wt% Ag is found to show the greatest antimicrobial activity and observed through the in vivo tests to reduce the microbial diversity colonizing the surface. PMID:26098413

  9. A unique in vivo approach for investigating antimicrobial materials utilizing fistulated animals

    Science.gov (United States)

    Berean, Kyle J.; Adetutu, Eric M.; Zhen Ou, Jian; Nour, Majid; Nguyen, Emily P.; Paull, David; McLeod, Jess; Ramanathan, Rajesh; Bansal, Vipul; Latham, Kay; Bishop-Hurley, Greg J.; McSweeney, Chris; Ball, Andrew S.; Kalantar-Zadeh, Kourosh

    2015-06-01

    Unique in vivo tests were conducted through the use of a fistulated ruminant, providing an ideal environment with a diverse and vibrant microbial community. Utilizing such a procedure can be especially invaluable for investigating the performance of antimicrobial materials related to human and animal related infections. In this pilot study, it is shown that the rumen of a fistulated animal provides an excellent live laboratory for assessing the properties of antimicrobial materials. We investigate microbial colonization onto model nanocomposites based on silver (Ag) nanoparticles at different concentrations into polydimethylsiloxane (PDMS). With implantable devices posing a major risk for hospital-acquired infections, the present study provides a viable solution to understand microbial colonization with the potential to reduce the incidence of infection through the introduction of Ag nanoparticles at the optimum concentrations. In vitro measurements were also conducted to show the validity of the approach. An optimal loading of 0.25 wt% Ag is found to show the greatest antimicrobial activity and observed through the in vivo tests to reduce the microbial diversity colonizing the surface.

  10. Campylobacter species in animal, food, and environmental sources, and relevant testing programs in Canada.

    Science.gov (United States)

    Huang, Hongsheng; Brooks, Brian W; Lowman, Ruff; Carrillo, Catherine D

    2015-10-01

    Campylobacter species, particularly thermophilic campylobacters, have emerged as a leading cause of human foodborne gastroenteritis worldwide, with Campylobacter jejuni, Campylobacter coli, and Campylobacter lari responsible for the majority of human infections. Although most cases of campylobacteriosis are self-limiting, campylobacteriosis represents a significant public health burden. Human illness caused by infection with campylobacters has been reported across Canada since the early 1970s. Many studies have shown that dietary sources, including food, particularly raw poultry and other meat products, raw milk, and contaminated water, have contributed to outbreaks of campylobacteriosis in Canada. Campylobacter spp. have also been detected in a wide range of animal and environmental sources, including water, in Canada. The purpose of this article is to review (i) the prevalence of Campylobacter spp. in animals, food, and the environment, and (ii) the relevant testing programs in Canada with a focus on the potential links between campylobacters and human health in Canada.

  11. The Fermi Guest Investigator program: Impactful Science and Groundbreaking Results

    Science.gov (United States)

    Ferrara, Elizabeth C.

    2016-04-01

    As an all-sky surveyor, the science impact from the Fermi Gamma-ray Space Telescope is limited by the number of scientists performing data analysis, and not by the number of objects observed by the spacecraft. To encourage this, the Fermi guest investigator (GI) program supports a variety of scientific inquiries that benefit overall Fermi science. The GI program also provides access to radio, optical, X-ray and VHE gamma-ray data and/or observing time, encouraging and enabling relevant multi-wavelength studies. This approach has allowed for new analyses and ideas to flourish, leading to world-class groundbreaking science and a number of unexpected discoveries. The program has also supported a number of multi-year, multi-wavelength observing programs resulting in a rich variety of publicly available resources. Here we describe the most significant results from the Fermi GI program, including those resulting from both sky-survey and target of opportunity pointed observations. We discuss the public resources the program has supported, both for broad-band data acquisition and for the development of new analysis methods and techniques. Additionally, we consider the ramifications of the existence of long-term multi-wavelength datasets, such as those enabled by the Fermi GI program, for future scientific inquiry.

  12. Using of Lab Animals as a Conceptual Model in to a Program of Non-formal Education

    OpenAIRE

    GENOVAKALOU, Petia; YOTOVSKA, Kamelia

    2014-01-01

    Оne of the most important questions in research ethics is the use of animals in research. It is very important to learn many aspects of laboratory animals' situations. The total number of animals used in 2013 in the EU amounted to 12.2 million. Mice, rats and rabbits represent 77.5% of the total number of animals used. Bulgaria has a modern legal framework for the protection of laboratory animals. The purpose of this study was to present a conceptual model of a program of non-formal education...

  13. Comparative evaluation of different anchoring techniques for synthetic cruciate ligaments. A biomechanical and animal investigation.

    Science.gov (United States)

    Letsch, R

    1994-01-01

    Under certain well-defined indications alloplastic material may be used in cruciate ligament surgery. The stability and survival of such a synthetic ligament is to a great extent dependent on the anchorage with which it is fastened to the bone. Most fixation methods have proved to be too weak or have revealed other essential drawbacks, resulting in clinical and experimental failure. A new ligament fixation device (LFD) was developed and tested biomechanically and in animal experiments. In the biomechanic investigation the new LFD was compared to single staples, double staples in the belt-buckle technique, and ligament guidance through additional bone tunnels (Z-technique). The tests were carried out on human cadaver knees, plastic bones, and dog stifle joints. The evaluated parameters were linear and maximum load, stiffness, and elongation. In addition, hysteresis tests were performed to assay the long-term resistance of the fixation. The tests showed a significant superiority of the LFD in all measured variables compared to the other anchorages. The pull-out strength, at 1866 +/- 43 N (cadaver knee), was about four times that for the single staple, and about twice as high as that for the double staple and Z-technique. The animal experiments were performed on German shepherd cross-breed dogs. In six animals the anterior cruciate ligaments were excised bilaterally and replaced by a 6-mm Trevira ligament, on one side anchored with staples in the Z-technique, on the other with the LFD. Postoperatively the dogs were allowed to move freely; no additional protection was employed. After 6 months the animals were sacrificed and the knees examined macroscopically, radiologically, microscopically, and by biomechanical testing. After half a year of implantation, the pull-out strength of the alloplastic ligament was 662 +/- 62 N for the LFD and 531 +/- 67 N for the staples. Three ligaments in the staple group and one in the LFD group had ruptured completely, and two ligaments

  14. VILLAGE’S HERDS: INVESTIGATING THE INTRODUCTION OF DOMESTIC ANIMALS AND PATTERNS OF ANIMAL HUSBANDRY AMONG INDIGENOUS PEOPLES IN AMAZONIA (RONDÔNIA

    Directory of Open Access Journals (Sweden)

    Felipe Ferreira Vander Velden

    2011-06-01

    Full Text Available This paper discuss the introduction of European domestic animals in indigenous villages in the Amazon, with particular stress on groups in Rondonia, specially the Karitiana, a Tupi-Arikém-speaking people that lives in the north of that state. In what concerns the history of Brazilian territorial conquest, marked by the ‘frentes pastoris’’ great narrative, and the present expansion – material and also ideological – of husbandry throughout Amazonia, this article points to many questions about the position of these animals – above all cattle – in indigenous peoples’ symbolical and material universes. Suggests new investigative possibilities, that inquires not only implemented experiences with animal husbandry in indigenous villages, but also desires and projects designed to future implementations.

  15. Three dimensional reconstruction of starling flocks: an empirical investigation of collective animal behavior

    Science.gov (United States)

    Giardina, Irene

    2009-03-01

    Bird flocking is a striking example of animal collective behaviour: thousands of birds gather above the roosting site, forming sharp-bordered flocks, which wheel and turn with remarkable coherence and synchronization. Despite an increasing theoretical interest, empirical investigations of collective motion have been limited so far by the difficulties of getting data on large systems. By means of stereoscopic photography and using statistical mechanics, optimization theory and computer vision techniques, we have measured for the first time the three-dimensional positions and trajectories of individual birds in groups of up to three thousands elements. This allowed us to analyze global morphological properties of the flocks, as well as structural and dynamical properties. Most notably, we investigated the nature of the inter-individual interaction. We found that the interaction between birds does not depend on their mutual metric distance, as most current models and theories assume, but rather on the topological distance (number of intermediate neighbors). In fact, we discovered that each individual interacts on average with a fixed number of neighbors (six-seven), rather than with all neighbors within a fixed metric distance. We argue that a topological interaction of this kind is indispensable to maintain flock's cohesion against the large density changes caused by external perturbations, typically predation. More recently, we characterized the velocity field, and computed dynamical observables. We showed that flocks exhibit long range correlations, which are a signature of their remarkable collective behavior.

  16. Elemental analysis of biological tissues of animal models in muscular dystrophies investigation

    International Nuclear Information System (INIS)

    Element concentrations in biological tissues of Dmdmdx/J and C57BL/6 J mice strains were determined using the neutron activation analysis technique. Samples of whole blood, bones and organs (heart and muscle) of these strains were irradiated in the IEA-R1 nuclear reactor at IPEN-CNEN/SP (Brazil). To perform this investigation biological samples of two-month-old adult females (n = 10) and males (n = 9) for Dmdmdx/J (dystrophic mice), and males (n 12) for C57BL/6 J (control group), originally obtained from the Jackson Laboratory (Maine, USA) and further inbred at IPEN-CNEN/SP (Sao Paulo, Brazil), were used. A significant change was observed in the analysis of the heart of dystrophic mice suggesting that this dysfunction affects severely the heart muscle. These data may, in the future, contribute to the healthcare area, in veterinary medicine and in the pharmaceutical industry allowing the evaluation of the best procedures in diagnosis, treatment and investigations of neuromuscular diseases (muscular dystrophy) of patients through the use of animal models. (author)

  17. Comparative investigations on animal cenuses of spruce and deciduous forests and of an old orchard - soil animals as bioindicators

    Energy Technology Data Exchange (ETDEWEB)

    Funke, W.; Herlitzius, H.; Jans, W.; Kraniz, V.; Lehle, E.; Ratajczak, L.; Stumpp, J.; Vogel, J.; Wanner, M.; Horsch, F.; Filby, W.G.; Fund, N.; Gross, S.; Hanisch, B.; Kilz, E.; Seidel, A.

    1988-04-01

    Investigations were carried out on Protozoa (Testacea, Ciliata) and Metazoa (Nematode, Annelida, Arthropoda) esp. of spruce stands. For comparisons deciduous forests and an old orchard were also used. In enchytraeid worms and in arthropods, esp. in dipterous imagines, liming and fertilizing of soil surface (in 1984/1984) had brought strong negative effects in regard of population density in the last years. Since 1987 these effects seem to turn into the opposite direction. Earth worms are naturally promoted by liming and fertilizing. Contaminations of soil surface by solutions of NaCl or by H/sub 2/SO/sub 4/ (in 1985) yielded considerable after-effects even 18 months later in a nematod worm coenosis, if comparisons are made with the data of control areas. In edaphic springtails, species numbers, abundances and diversities of coenoses now had nearly normalized (two years after the contaminations). But negative effects after contaminations with the synthetic pyrethroid Cypermethrin (Ripcord) seem to be unchanged up to now.

  18. Summary of multi-core hardware and programming model investigations

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, Suzanne Marie; Pedretti, Kevin Thomas Tauke; Levenhagen, Michael J.

    2008-05-01

    This report summarizes our investigations into multi-core processors and programming models for parallel scientific applications. The motivation for this study was to better understand the landscape of multi-core hardware, future trends, and the implications on system software for capability supercomputers. The results of this study are being used as input into the design of a new open-source light-weight kernel operating system being targeted at future capability supercomputers made up of multi-core processors. A goal of this effort is to create an agile system that is able to adapt to and efficiently support whatever multi-core hardware and programming models gain acceptance by the community.

  19. Investigations on x-ray luminescence CT for small animal imaging

    Science.gov (United States)

    Badea, C. T.; Stanton, I. N.; Johnston, S. M.; Johnson, G. A.; Therien, M. J.

    2012-03-01

    X-ray Luminescence CT (XLCT) is a hybrid imaging modality combining x-ray and optical imaging in which x-ray luminescent nanophosphors (NPs) are used as emissive imaging probes. NPs are easily excited using common CT energy x-ray beams, and the NP luminescence is efficiently collected using sensitive light-based detection systems. XLCT can be recognized as a close analog to fluorescence diffuse optical tomography (FDOT). However, XLCT has remarkable advantages over FDOT due to the substantial excitation penetration depths provided by x-rays relative to laser light sources, long-term photo-stability of NPs, and the ability to tune NP emission within the NIR spectral window. Since XCLT uses an x-ray pencil beam excitation, the emitted light can be measured and back-projected along the x-ray path during reconstruction, where the size of the x-ray pencil beam determines the resolution for XLCT. In addition, no background signal competes with NP luminescence (i.e., no auto fluorescence) in XLCT. Currently, no small animal XLCT system has been proposed or tested. This paper investigates an XLCT system built and integrated with a dual source micro-CT system. A novel sampling paradigms that results in more efficient scanning is proposed and tested via simulations. Our preliminary experimental results in phantoms indicate that a basic CT-like reconstruction is able to recover a map of the NP locations and differences in NP concentrations. With the proposed dual source system and faster scanning approaches, XLCT has the potential to revolutionize molecular imaging in preclinical studies.

  20. Using the Ferret as an Animal Model for Investigating Influenza Antiviral Effectiveness

    OpenAIRE

    Oh, Ding Y.; Hurt, Aeron C.

    2016-01-01

    The concern of the emergence of a pandemic influenza virus has sparked an increased effort toward the development and testing of novel influenza antivirals. Central to this is the animal model of influenza infection, which has played an important role in understanding treatment effectiveness and the effect of antivirals on host immune responses. Among the different animal models of influenza, ferrets can be considered the most suitable for antiviral studies as they display most of the human-l...

  1. Helicobacter pylori-infected animal models are extremely suitable for the investigation of gastric carcinogenesis

    OpenAIRE

    Kodama, Masaaki; Murakami, Kazunari; Sato, Ryugo; Okimoto, Tadayoshi; Nishizono, Akira; Fujioka, Toshio

    2005-01-01

    Although various animal models have been developed to clarify gastric carcinogenesis, apparent mechanism of gastric cancer was not clarified in recent years. Since the recognition of the pathogenicity of Helicobacter pylori (H pylori), several animal models with H pylori infection have been developed to confirm the association between H pylori and gastric cancer. Nonhuman primate and rodent models were suitable for this study. Japanese monkey model revealed atrophic gastritis and p53 mutation...

  2. Animal Assisted Therapy and the Reading Education Assistance Dogs[RTM] (R.E.A.D.) Program as Perceived by Volunteer R.E.A.D. Facilitators: A National Study

    Science.gov (United States)

    Swift, Catherine Hayes

    2009-01-01

    This study investigated the demographics and perceptions of participants who utilize animals in academic programs, specifically the volunteers who use dogs to work with at-risk children in reading programs. It presented an argument for incorporating research-supported elements of reading tutor skills into the volunteer tutor training for the…

  3. Investigation of nutriactive phytochemical - gamma-oryzanol in experimental animal models.

    Science.gov (United States)

    Szcześniak, K A; Ostaszewski, P; Ciecierska, A; Sadkowski, T

    2016-08-01

    Gamma-oryzanol (GO) is an abundant dietary antioxidant that is considered to have beneficial effects in cardiovascular disease, cancer and diabetes. Other potential properties of GO include inhibition of gastric acid secretion and decreased post-exercise muscle fatigue. GO is a unique mixture of triterpene alcohol and sterol ferulates present in rice bran oil, a byproduct of rice processing. GO has been studied by many researchers over the last three decades. In particular, the utility of GO supplementation has been documented in numerous animal models. A large variety of species was examined, and various experimental methodologies and targets were applied. The aim of this study was to summarize the body of research on GO supplementation in animals and to examine possible mechanisms of GO action. Furthermore, while the safety of GO supplementation in animals has been well documented, studies demonstrating pharmacokinetics, pharmacodynamics and efficiency are less clear. The observed differences in these findings are also discussed. PMID:26718022

  4. An Evaluation of the Use of Student-Centred Investigations in Teaching Comparative Animal Physiology to Undergraduates.

    Science.gov (United States)

    Spicer, John I.; Bonsall, Marie

    1995-01-01

    Taught comparative animal physiology to undergraduates (n=31) using student-centered (open-ended) investigations in small groups. Questionnaires and discussion found that students appeared to value learning through their own experience as highly as they did being taught and valued the opportunity to establish and develop skills less easily…

  5. RCRA facility investigation and corrective measures study program

    International Nuclear Information System (INIS)

    Two case studies of U.S. EPA-required RFI/CMS programs will be summarized and related in this paper. The actual FRI/CMS process and how this affected tow facilities will be explained. The type of effort needed to undertake the RFI/CMS program and attendant costs will be described. This paper is intended to convey the working of the RFI/CMS process as well as point out pitfalls and how to avoid them. The facility owner than undertakes a RCRA Facility Investigation to determine the type and impact of SWMUs on-site. This report determines the need for additional interim corrective measures; or, if no adverse impact is found, then no further action is recommended. This leads to the development of a CMS initiated by the facility owner. This study includes financial assessment, conceptual designs, liability assessments and remedial assessments. The regulatory impact and cost impact on industrial plants (such as petrochemical plants) is just now being realized. The cost for conducting the RFI/CMS Assessment, depending upon how many old SWMUs are present and can be readily identified, could range up to $500,000 or more

  6. PROGRAM OF INVESTIGATION ON THE TAMMEF SYSTEM APPLICATION METHODS

    Directory of Open Access Journals (Sweden)

    F. Bacci

    2009-12-01

    Full Text Available The TAMMEF System consists of the clinical application of electromagnetic fields piloted at a low frequency by music signals, with simultaneous audition of the same. The working hypothesis expects that the ascertained pain-relieving and therapeutical effects do not depend only on the treatment but also the patient’s disposition. Accordingly, each subject is to be examined by a psychologist, who should also advise whether it may be proper to explain to him/her the music-fields correlation. Conversely, the choice of the pilot music piece, obtained from publications, is to be appraised by a musicologist. Taking into account such conditions and necessities, the criteria for laying out the said program of investigation aimed at verifying the given hypothesis are hereby reported.

  7. Investigations into the effect of immunostimulating drugs on the immune system of irradiated experimental animals

    International Nuclear Information System (INIS)

    In experiments with mice and pigs a sublethal irradiation before vaccination proved to be by far more efficient than an irradiation with the same dose following vaccination. In the irradiated animals a retarded beginning of the immune response compared with the controls was observed. In the experiments with mice positive effects of the adjuvant azimexon and levamisol on the radiation induced immunosuppression was seen. In the experiments with pigs the radiation iduced immunosuppression was completely abolished by addition of incomplete Freund adjuvant to the antigen. Azimexon as adjuvant was efficient both when given before or after exposition. Post-endotoxic serum from BCG-infected animals (BCG/ET) had only a weak effect in animals immunized before exposition. Serum immunoglobulin levels of pigs were stable against irradiation and application of immunomodulating agents. Stimulation effects of the irradiation on the antibody response were observed in mice and pigs if the animals were first immunized and irradiated afterwards. In the irradiated pigs the mitogenic stimulation of T and B cells was depressed. After application of azimexon the stimulation of T cells was significantly increased in irradiated pigs; the impaired B cell stimulation, however, remained unaltered. By using the monoclonal antibody technique functionally distinct subpopulations of peripherals lymphocytes in swine were detected, each showing a different sensibility towards in vivo irradiation. (orig.) With 10 refs., 21 figs

  8. Helicobacter pylori-infected animal models are extremely suitable for the investigation of gastric carcinogenesis

    Institute of Scientific and Technical Information of China (English)

    Masaaki Kodama; Kazunari Murakami; Ryugo Sato; Tadayoshi Okimoto; Akira Nishizono; Toshio Fujioka

    2005-01-01

    Although various animal models have been developed to clarify gastric carcinogenesis, apparent mechanism of gastric cancer was not clarified in recent years. Since the recognition of the pathogenicity of Helicobacter pylori (Hpylori), several animal models with Hpylori infection have been developed to confirm the association between Hpylori and gastric cancer. Nonhuman primate and rodent models were suitable for this study. Japanese monkey model revealed atrophic gastritis and p53mutation after long-term infection of Hpylori. Mongolian gerbil model showed the development of gastric carcinoma with H pylori infection alone, as well as with combination of chemical carcinogens, such as N-methylN-nitrosourea and N-methyl-N-nitro-N'-nitrosoguanidine.The histopathological changes of these animal models after Hpylori inoculation are closely similar to those in human beings with Hpylori infection. Eradication therapy attenuated the development of gastric cancer in Hpyloriinfected Mongolian gerbil. Although several features of animal models differ from those seen in human beings,these experimental models provide a starting point for further studies to clarify the mechanism of gastric carcinogenesis as a result of Hpylori infection and assist the planning of eradication therapy to prevent gastric carcinoma.

  9. Investigation of exposure to Extremely Low Frequency (ELF) magnetic and electric fields: Ongoing animal studies

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, L.E.

    1994-03-01

    There is now convincing evidence from a large number of laboratories, that exposure to extremely low frequency (ELF) magnetic and electric fields produces biological responses in animals. Many of the observed effects appear to be directly or indirectly associated with the neural or neuroendocrine systems. Such effects include increased neuronal excitability, chemical and hormonal changes in the nervous system, altered behavioral responses, some of which are related to sensing the presence of the field, and changes in endogenous biological rhythms. Additional indices of general physiological status appear relatively unaffected by exposure, although effects have occasionally been described in bone growth and fracture repair, reproduction and development, and immune system function. A major current emphasis in laboratory research is to determine whether or not the reported epidemiological studies that suggest an association between EMF exposure and risk of cancer are supported in studies using animal models. Three major challenges exist for ongoing research: (1) knowledge about the mechanisms underlying observed bioeffects is incomplete, (2) researchers do not as yet understand what physical aspects of exposure produce biological responses, and (3) health consequences resulting from ELF exposure are unknown. Although no animal studies clearly demonstrate deleterious effects of ELF fields, several are suggestive of potential health impacts. From the perspective of laboratory animal studies, this paper will discuss biological responses to ELF magnetic and/or electric field exposures.

  10. Clinical investigations and animal experiments on the problem of hemolysis under extracorporeal blood irradiation

    International Nuclear Information System (INIS)

    In the time from October 1975 to March 1976, extracorporeal blood irradiation as a therapy against chronic lymphiatic leukemia was carried out on 12 patients. Before and after the irradiation, the concentrations of free heamoglobin, haptoglobin, and haemopexin in the serum were determined. All three parameters were not significantly changed by extracorporeal blood irradiation with transitory doses of up to 13,190 rad. In the time from April 1976 to May 1977, in an animal experiment, the blood of three sheep and a goat was irradiated extracorporeally. The first 3 animals died because of complications induced by anaesthesia and had, until their death, maximally only received 14,956 rad. The 4th animal first developed an aenemia. Only when it had been massively irradiated with a dose of 137,000 rad during the last three weeks it died with a haemoglobin concentration of 4.3 g/100 ml with 2.9 million erythrocytes. This animal had received a total irradiation dose of 466,566 rad. Extracorporeal fractioned blood irradiation with transitory doses of less than 1000 rad which is completely sufficient to destroy the lymphocytes is relatively undangerous for the erythrocytes. As the erythrocytes have a relatively long life of appr. 100 days, they accumulate the radiation dose. Each population of erythrocytes is exposed only 14 times when irradiated weekly. After this, the dose applied has to be calculated again. If it is below 25,000 rad the survival time of erythrocytes is not shortened and the extracorporeal blood irradiation is a relatively safe treatment method for chronic lymphatic leukaemia which can be applied restrictedly in large centres having the irradiation equipment which, however, has, in contrast to cylostatics, no systemic side effects. (orig./AJ)

  11. Investigation of biofilm formation in vitro ability of Listeria monocytogenes strains isolated from animals

    OpenAIRE

    Milanov Dubravka; Ašanin Ružica; Mišić D.; Vidić Branka; Ratajac R.

    2007-01-01

    Listeria monocytogenes is the causative agent of listeriosis in humans and animals and an important food-born pathogen. Control of its presence in food processing plants, particularly on sites where food contamination is expected, is of paramount importance with respect to food safety and protection of human health. Numerous studies demonstrated that this organism can be isolated during several months, even several years, from diverse sites in food processing plants, which is due to its abili...

  12. An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure

    Institute of Scientific and Technical Information of China (English)

    María Jesús Tu(n)ón; Marcelino Alvarez; Jesús M Culebras; Javier González-Gallego

    2009-01-01

    Acute hepatic failure (AHF) is a severe liver injury accompanied by hepatic encephalopathy which causes multiorgan failure with an extremely high mortality rate, even if intensive care is provided. Management of severe AHF continues to be one of the most challenging problems in clinical medicine. Liver transplantation has been shown to be the most effective therapy, but the procedure is limited by shortage of donor organs. Although a number of clinical trials testing different liver assist devices are under way, these systems alone have no significant effect on patient survival and are only regarded as a useful approach to bridge patients with AHF to liver transplantation. As a result, reproducible experimental animal models resembling the clinical conditions are still needed. The three main approaches used to create an animal model for AHF are: surgical procedures, toxic liver injury and infective procedures. Most common models are based on surgical techniques (total/partial hepatectomy, complete/transient devascularization) or the use of hepatotoxic drugs (acetaminophen, galactosamine, thioacetamide, and others), and very few satisfactory viral models are available. We have recently developed a viral model of AHF by meansof the inoculation of rabbits with the virus of rabbit hemorrhagic disease. This model displays biochemical and histological characteristics, and clinical features that resemble those in human AHF. In the present article an overview is given of the most widely used animal models of AHF, and their main advantages and disadvantages are reviewed.

  13. An Interactive Graphics Program for Investigating Digital Signal Processing.

    Science.gov (United States)

    Miller, Billy K.; And Others

    1983-01-01

    Describes development of an interactive computer graphics program for use in teaching digital signal processing. The program allows students to interactively configure digital systems on a monitor display and observe their system's performance by means of digital plots on the system's outputs. A sample program run is included. (JN)

  14. A framework program for the teaching of alternative methods (replacement, reduction, refinement) to animal experimentation

    OpenAIRE

    Daneshian, Mardas; Akbarsha, Mohammad A.; Blaauboer, Bas; Caloni, Francesca; Cosson, Pierre; Curren, Rodger; Goldberg, Alan; Gruber, Franz; Ohl, Frauke; Pfaller, Walter; Van der Valk, Jan; Vinardell, Pilar; Zurlo, Joanne; Hartung, Thomas; Leist, Marcel

    2011-01-01

    Development of improved communication and education strategies is important to make alternatives to the use of animals, and the broad range of applications of the 3Rs concept better known and understood by different audiences. For this purpose, the Center for Alternatives to Animal Testing in Europe (CAAT-Europe) together with the Transatlantic Think Tank for Toxicology (t(4)) hosted a three-day workshop on "Teaching Alternative Methods to Animal Experimentation". A compilation of the recomme...

  15. Investigation of the inorganic and organic phosphorus forms in animal manure.

    Science.gov (United States)

    Pagliari, Paulo H; Laboski, Carrie A M

    2012-01-01

    The most viable way to beneficially use animal manure on most farms is land application. Over the past few decades, repeated manure application has shown adverse effects on environmental quality due to phosphorus (P) runoff with rainwater, leading to eutrophication of aquatic ecosystems. Improved understanding of manure P chemistry may reduce this risk. In this research, 42 manure samples from seven animal species (beef and dairy cattle, swine, chicken, turkey, dairy goat, horse, and sheep) were sequentially fractionated with water, NaHCO₃, NaOH, and HCl. Inorganic (P(i)), organic (P(o)), enzymatic hydrolyzable (P(e); monoester-, DNA-, and phytate-like P), and nonhydrolyzable P were measured in each fraction. Total dry ash P (P(t)) was measured in all manures. Total fractionated P (P(ft)) and total P(i) (P(it)) showed a strong linear relationship with P(t). However, the ratios between P(ft)/P(t) and P(it)/P(t) varied from 59 to 117% and from 28 to 96%, respectively. Water and NaHCO₃ extracted most of the P(i) in manure from ruminant+horse, whereas in nonruminant species a large fraction of manure P was extracted in the HCl fraction. Manure P(e) summed over all fractions (P(et)) accounted for 41 to 69% of total P(0) and 4 to 29% of P(t). The hydrolyzable pool in the majority of the manures was dominated by phytate- and DNA-like P in water, monoester- and DNA-like P in NaHCO₃, and monoester- and phytate-like P in NaOH and HCl fractions. In conclusion, if one assumes that the P(et) and P(it) from the fractionation can become bioavailable, then from 34 to 100% of P(t) in animal manure would be bioavailable. This suggests the need for frequent monitoring of manure P for better manure management practices.

  16. Authenticity and quality of animal origin food investigated by stable-isotope ratio analysis.

    Science.gov (United States)

    Vinci, Giuliana; Preti, Raffaella; Tieri, Alessandra; Vieri, Simone

    2013-02-01

    Authentication of a food product is the procedure by which it is verified that the product matches the statements on the label, and that it conforms to what is established by regulations. This testing process includes analysis of the ingredients, determination of the geographical origin, and examination of the production methods. In particular, the use of rapid, effective and reliable analytical methods, when correctly applied to verify the authenticity and the traceability of the product, represents a valuable and irreplaceable tool for the authorities to carry out control functions. Tools and methodologies from scientific innovation and technological evolution can help to quickly locate particularly sophisticated frauds and adulterations. The feeding regime of livestock is a fundamental issue for the properties and safety of animal origin food, but this regime is often hidden from the consumer, making the zootechnical sector more prone to fraudulent practices. This review reports the results recently obtained in authentication of animal origin food by the application of stable-isotope ratio analysis, the most promising analytical technique in this field.

  17. Using the Ferret as an Animal Model for Investigating Influenza Antiviral Effectiveness.

    Science.gov (United States)

    Oh, Ding Y; Hurt, Aeron C

    2016-01-01

    The concern of the emergence of a pandemic influenza virus has sparked an increased effort toward the development and testing of novel influenza antivirals. Central to this is the animal model of influenza infection, which has played an important role in understanding treatment effectiveness and the effect of antivirals on host immune responses. Among the different animal models of influenza, ferrets can be considered the most suitable for antiviral studies as they display most of the human-like symptoms following influenza infections, they can be infected with human influenza virus without prior viral adaptation and have the ability to transmit influenza virus efficiently between one another. However, an accurate assessment of the effectiveness of an antiviral treatment in ferrets is dependent on three major experimental considerations encompassing firstly, the volume and titer of virus, and the route of viral inoculation. Secondly, the route and dose of drug administration, and lastly, the different methods used to assess clinical symptoms, viral shedding kinetics and host immune responses in the ferrets. A good understanding of these areas is necessary to achieve data that can accurately inform the human use of influenza antivirals. In this review, we discuss the current progress and the challenges faced in these three major areas when using the ferret model to measure influenza antiviral effectiveness. PMID:26870031

  18. Using the ferret as an animal model for investigating influenza antiviral effectiveness

    Directory of Open Access Journals (Sweden)

    Ding Yuan Oh

    2016-02-01

    Full Text Available The concern of the emergence of a pandemic influenza virus has sparked an increased effort towards the development and testing of novel influenza antivirals. Central to this is the animal model of influenza infection, which has played an important role in understanding treatment effectiveness and the effect of antivirals on host immune responses. Among the different animal models of influenza, ferrets can be considered the most suitable for antiviral studies as they display most of the human-like symptoms following influenza infections, they can be infected with human influenza virus without prior viral adaptation and have the ability to transmit influenza virus efficiently between one another. However, an accurate assessment of the effectiveness of an antiviral treatment in ferrets is dependent on three major experimental considerations encompassing firstly, the volume and titre of virus, and the route of viral inoculation. Secondly, the route and dose of drug administration, and lastly, the different methods used to assess clinical symptoms, viral shedding kinetics and host immune responses in the ferrets. A good understanding of these areas is necessary to achieve data that can accurately inform the human use of influenza antivirals. In this review, we discuss the current progress and the challenges faced in these three major areas when using the ferret model to measure influenza antiviral effectiveness.

  19. The role of veterinary epidemiology in combating infectious animal diseases on a global scale: the impact of training and outreach programs.

    Science.gov (United States)

    Salman, M D

    2009-12-01

    The effectiveness of detection and control of highly contagious animal diseases is dependent on a solid understanding of their nature and implementation of scientifically sound methods by people who are well trained. The implementation of specific detection methods and tools requires training and application in natural as well as field conditions. The aim of this paper is to present the design and implementation of training in disease investigation and basic veterinary epidemiology in selected countries using the Highly Pathogenic Avian Influenza (HPAI) H5N1 Asia strain as a disease detection model. Indonesia, Egypt, Nigeria, Turkey, and Vietnam were each identified as either a priority country where AI was spreading rapidly or a country at risk for infection. In each of these countries, a training program on epidemiological concepts, field investigation methodology, and detection of H5N1 Asia strain cases was conducted. This report includes the impact of these training sessions on national animal health programs, including follow-up activities of animal health officers who went through these training sessions.

  20. Investigations of HPA Function and the Enduring Consequences of Stressors in Adolescence in Animal Models

    Science.gov (United States)

    McCormick, Cheryl M.; Mathews, Iva Z.; Thomas, Catherine; Waters, Patti

    2010-01-01

    Developmental differences in hypothalamic-pituitary-adrenal (HPA) axis responsiveness to stressors and ongoing development of glucocorticoid-sensitive brain regions in adolescence suggest that similar to the neonatal period of ontogeny, adolescence may also be a sensitive period for programming effects of stressors on the central nervous system.…

  1. The focus and investigation challenges for influence of animal and plant products downstream from tailing dam SASA

    OpenAIRE

    Mitevska-Georgievska, Vesna; Krstev, Boris; Krstev, Aleksandar; Golomeova, Mirjana; Golomeov, Blagoj; Zajkova-Paneva, Vesna; Danevski, Tome

    2013-01-01

    The current activity in the Sasa mine and flotation of useful galena and sphalerite producing metallic lead and zinc for market, are reason for possible troubles from tailing dam-pond and surrounding river for influence of animal and plant products. Specially for milk, potato, tomato, paprika, lentil, carrot and other product very important for human needs. In this paper will be present results of investigations for heavy metal presence in these products. Statistical analysis and other ...

  2. Selecting Television Programs for Language Learning: Investigating Television Programs from the Same Genre

    Directory of Open Access Journals (Sweden)

    Stuart Webb

    2011-06-01

    Full Text Available The scripts of 288 television episodes were analysed to determine the extent to which vocabulary reoccurs in television programs from the same subgenres and unrelated television programs from different genres. Episodes from two programs from each of the following three subgenres of the American drama genre: medical, spy/action, and criminal forensic investigation were compared with different sets of random episodes. The results showed that although there were an equivalent number of running words in each set of episodes, the episodes from programs within the same subgenre contained fewer word families than random programs. The findings also showed that low frequency word families (4000-14,000 levels reoccur more often in programs within the same subgenre. Together the results indicate that watching programs within the same subgenre may be an effective approach to language learning with television because it reduces the lexical demands of viewing and increases the potential for vocabulary learning.Los guiones de 288 episodios televisivos se analizaron para determinar el alcance de la recursividad del vocabulario en programas de televisión del mismo subgénero y en programas no relacionados de géneros diferentes. Se compararon episodios de tres subgéneros del drama americano: médico, de espías/acción y de investigación forense, con varios grupos de episodios elegidos al azar. Los resultados muestran que, aunque el número de palabras en cada grupo de episodios era equivalente, los episodios del mismo subgénero contienen menos familias de palabras que aquellos elegidos al azar. Los hallazgos mostraron que las familias de baja frecuencia (niveles de 4.000-14.000 se repiten con más frecuencia en los programas del mismo subgénero. En conjunto, los resultados indican que el visionado de programas del mismo subgénero puede ser un método efectivo para aprender el lenguaje por medio de la televisión porque reduce la demanda léxica de la

  3. Investigating Difficulties of Learning Computer Programming in Saudi Arabia

    Science.gov (United States)

    Alakeel, Ali M.

    2015-01-01

    Learning computer programming is one of the main requirements of many educational study plans in higher education. Research has shown that many students face difficulties acquiring reasonable programming skills during their first year of college. In Saudi Arabia, there are twenty-three state-owned universities scattered around the country that…

  4. In-vivo laser induced urethral stricture animal model for investigating the potential of LDR-brachytherapy

    Science.gov (United States)

    Sroka, Ronald; Lellig, Katja; Bader, Markus; Stief, Christian; Weidlich, Patrick; Wechsel, G.; Assmann, Walter; Becker, R.; Fedorova, O.; Khoder, Wael

    2015-02-01

    Purpose: Treatment of urethral strictures is a major challenge in urology. For investigation of different treatment methods an animal model was developed by reproducible induction of urethral strictures in rabbits to mimic the human clinical situation. By means of this model the potential of endoluminal LDR brachytherapy using β-irradiation as prophylaxis of recurrent urethral strictures investigated. Material and Methods: A circumferential urethral stricture was induced by energy deposition using laser light application (wavelength λ=1470 nm, 10 W, 10 s, applied energy 100 J) in the posterior urethra of anaesthetized New Zealand White male rabbits. The radial light emitting fiber was introduced by means of a children resectoscope (14F). The grade of urethral stricture was evaluated in 18 rabbits using videourethroscopy and urethrography at day 28 after stricture induction. An innovative catheter was developed based on a β-irradiation emitting foil containing 32P, which was wrapped around the application system. Two main groups (each n=18) were separated. The "internal urethrotomy group" received after 28days of stricture induction immediately after surgical urethrotomy of the stricture the radioactive catheter for one week in a randomized, controlled and blinded manner. There were 3 subgroups with 6 animals each receiving 0 Gy, 15 Gy and 30 Gy. In contrast animals from the "De Nuovo group" received directly after the stricture induction (day 0) the radioactive catheter also for the duration of one week divided into the same dose subgroups. In order to determine the radiation tolerance of the urethral mucosa, additional animals without any stricture induction received a radioactive catheter applying a total dose of 30 Gy (n=2) and 15 Gy (n=1). Cystourethrography and endoscopic examination of urethra were performed on all operation days for monitoring treatment progress. Based on these investigation a classification of the stricture size was performed and

  5. Developing Children's Awareness of the Human-Animal Bond: An Assessment of the Experiences and Benefits that Children Receive in the United Animal Nation's Humane Education Ambassador Readers (HEAR) Program

    Science.gov (United States)

    Stokes, Laura

    2009-01-01

    In 2007, the United Animal Nations (UAN) launched the Humane Education Ambassador Readers (HEAR), an innovation that focused on mitigation of animal suffering through education. In the HEAR program, adult volunteers read carefully selected story books to children in grades 3-6 in schools or other educational settings, and hold discussions with the…

  6. VB中的动画编程技术%Animation Programming in VB

    Institute of Scientific and Technical Information of China (English)

    林立云

    2011-01-01

    Animated movement is to create a visual effect,with the rapid development of computers and networks,multimedia technology has been widely used network animation is not an integral part of life,adding animation would make the whole application look more beautiful,especially some of the interesting use of animation,you can make the software interface with a lively effect.This paper describes the animating principle and method.%动画就是创造出运动的视觉效果,随着计算机及网络的飞速发展,多媒体技术得到了广泛的应用,动画是网络生活中不可以缺少的一部分,加入动画效果会使整个应用软件看起来更加美观,尤其是一些生动有趣动画效果的运用,可以使软件界面具有生动活泼的效果。本文介绍了动画的制作原理及方法。

  7. Investigation of independence in inter-animal tumor-type occurrences within the NTP rodent-bioassay database

    Energy Technology Data Exchange (ETDEWEB)

    Bogen, K.T. [Lawrence Livermore National Lab., CA (United States); Seilkop, S. [Analytical Sciences, Inc., Durham, NC (United States)

    1993-05-01

    Statistically significant elevation in tumor incidence at multiple histologically distinct sites is occasionally observed among rodent bioassays of chemically induced carcinogenesis. If such data are to be relied on (as they have, e.g., by the US EPA) for quantitative cancer potency assessment, their proper analysis requires a knowledge of the extent to which multiple tumor-type occurrences are independent or uncorrelated within individual bioassay animals. Although difficult to assess in a statistically rigorous fashion, a few significant associations among tumor-type occurrences in rodent bioassays have been reported. However, no comprehensive studies of animal-specific tumor-type occurrences at death or sacrifice have been conducted using the extensive set of available NTP rodent-bioassay data, on which most cancer-potency assessment for environmental chemicals is currently based. This report presents the results of such an analysis conducted on behalf of the National Research Council`s Committee on Risk Assessment for Hazardous Air Pollutants. Tumor-type associations among individual animals were examined for {approximately}2500 to 3000 control and {approximately}200 to 600 treated animals using pathology data from 62 B6C3F1 mouse studies and 61 F/344N rat studies obtained from a readily available subset of the NTP carcinogenesis bioassay database. No evidence was found for any large correlation in either the onset probability or the prevalence-at-death or sacrifice of any tumor-type pair investigated in control and treated rats and niece, although a few of the small correlations present were statistically significant. Tumor-type occurrences were in most cases nearly independent, and departures from independence, where they did occur, were small. This finding is qualified in that tumor-type onset correlations were measured only indirectly, given the limited nature of the data analyzed.

  8. Pointer Animation Implementation at Development of Multimedia Learning of Java Programming

    Science.gov (United States)

    Rusli, Muhammad; Atmojo, Yohanes Priyo

    2015-01-01

    This research represents the development research using the references of previous research results related to the development of interactive multimedia learning (learner controlled), specially about the effectiveness and efficiency of multimedia learning of a content that developed by pointer animation implementation showing the content in…

  9. ACM SIGGRAPH Video Review Issue 152, SIGGRAPH 2005 Animation Theater Program PART 2

    DEFF Research Database (Denmark)

    2005-01-01

    Pre-operative evaluation of surgical strategies is of utmost importancein many areas of surgery. This is especially true for surgeryin congenital heart disease, where the complex morphology variesfrom individual to individual. This animation shows how interactive,real-time computer graphics...

  10. Lymphatic territories (lymphosomes in a canine: an animal model for investigation of postoperative lymphatic alterations.

    Directory of Open Access Journals (Sweden)

    Hiroo Suami

    Full Text Available BACKGROUND: Lymph node dissection is often performed as a part of surgical treatment for breast cancer and malignant melanoma to prevent malignant cells from traveling via the lymphatic system. Currently little is known about postoperative lymphatic drainage pattern alterations. This knowledge may be useful for management of recurrent cancer and prevention of breast cancer related lymphedema. We mapped the complete superficial lymphatic system of a dog and used this canine model to perform preliminary studies of lymphatic architectural changes in postoperative condition. METHODS: Lymphatic territories (lymphosomes were mapped with 4 female mongrel carcasses using an indocyanine green (ICG fluorescent lymphography and a radiographic microinjection technique. Two live dogs were then subjected to unilateral lymph node dissection of lymph basins of the forelimb, and ICG lymphography and lymphangiogram were performed 6 months after the surgery to investigate lymphatic changes. Lymphatic patterns in the carcass were then compared with postoperative lymphatic patterns in the live dogs. RESULTS: Ten lymphosomes were identified, corresponding with ten lymphatic basins. Postoperative fluorescent lymphographic images and lymphangiograms in the live dogs revealed small caliber lymphatic network fulfilling gaps in the surgical area and collateral lymphatic vessels arising from the network connecting to lymph nodes in the contralateral and ipsilateral neck in one dog and the ipsilateral subclavicular vein in another dog. CONCLUSION: Our canine lymphosome map allowed us to observe lymphatic collateral formations after lymph node dissection in live dogs. This canine model may help clarify our understanding of postoperative lymphatic changes in humans in future studies.

  11. Adulthood Animal Abuse among Women Court-Referred to Batterer Intervention Programs

    Science.gov (United States)

    Febres, Jeniimarie; Shorey, Ryan C.; Brasfield, Hope; Zucosky, Heather C.; Ninnemann, Andrew; Elmquist, Joanna; Bucossi, Meggan M.; Andersen, Shawna M.; Schonbrun, Yael C.; Stuart, Gregory L.

    2012-01-01

    The substantial increase in the enrollment of women in batterer intervention programs (BIPs) over the past 30 years has greatly outpaced research on women who perpetrate intimate partner violence (IPV). As a result, it is unknown whether existing programs, which were originally designed to treat male perpetrators, are effective at preventing…

  12. Selecting Television Programs for Language Learning: Investigating Television Programs from the Same Genre

    Science.gov (United States)

    Webb, Stuart

    2011-01-01

    The scripts of 288 television episodes were analysed to determine the extent to which vocabulary reoccurs in television programs from the same subgenres and unrelated television programs from different genres. Episodes from two programs from each of the following three subgenres of the American drama genre: medical, spy/action, and criminal…

  13. Identifying and characterizing chemical skin sensitizers without animal testing: Colipa's research and method development program.

    Science.gov (United States)

    Aeby, P; Ashikaga, T; Bessou-Touya, S; Schepky, A; Gerberick, F; Kern, P; Marrec-Fairley, M; Maxwell, G; Ovigne, J-M; Sakaguchi, H; Reisinger, K; Tailhardat, M; Martinozzi-Teissier, S; Winkler, P

    2010-09-01

    The sensitizing potential of chemicals is usually identified and characterized using one of the available animal test methods, such as the mouse local lymph node assay. Due to the increasing public and political concerns regarding the use of animals for the screening of new chemicals, the Colipa Skin Tolerance Task Force collaborates with and/or funds research groups to increase and apply our understanding of the events occurring during the acquisition of skin sensitization. Knowledge gained from this research is used to support the development and evaluation of novel alternative approaches for the identification and characterization of skin sensitizing chemicals. At present one in chemico (direct peptide reactivity assay (DPRA)) and two in vitro test methods (cell based assays (MUSST and h-CLAT)) have been evaluated within Colipa inter-laboratory ring trials and accepted by the European Centre for the Validation of Alternative Methods (ECVAM) for pre-validation. Data from all three test methods will be used to support the development of testing strategy approaches for skin sensitizer potency prediction. The replacement of the need for animal testing for skin sensitization risk assessment is viewed as ultimately achievable and the next couple of years should set the timeline for this milestone. PMID:20624454

  14. Aquatic Species Program review: proceedings of principal investigators meeting

    Energy Technology Data Exchange (ETDEWEB)

    1985-06-01

    The purpose of the Aquatic Species Program is to improve the productivity, conversion to fuels, and cost efficiency of aquatic plant culture technologies. The emphasis of the program is on developing a mass culture technology for cultivating oil-yielding microalgae in the American southwest. A technical and economic analysis indicated that such a concept would be feasible if (1) lipid yields from microalgae are improved, (2) there is sufficient saline water for large-scale development, and (3) microalgal lipids can be economically converted to conventional fuels. It was determined that fuels from microalgal lipids presented better options than converting the microalgal biomass to either alcohols or methane. All lipids can potentially be catalytically converted to gasoline, or the fatty acids can be converted to substitute diesel fuels. The Southwest has the necessary low, flat, underutilized lands, and carbon dioxide is available from either natural deposits or flue gas from industrial plants. The amount of saline water available will probably determine how much fuel can be produced from aquatic species, and this question should be answered during 1985. The largest constraint of this technology is the economical production of an oil-rich microalgal feedstock. The agenda for the review was divided into four sections: species selection and characterization, applied physiological studies, outdoor mass cultivation, and systems design and analysis. Papers from these presentations are included in these proceedings. Program advances were reported in the areas of species collection and selection, modulated light physiology, mass culture yields, harvesting of microalgae, mass culture facility design and analysis, and assessments on fuel options from microalgae. Separate abstracts have been prepared for each paper for inclusion in the Energy Data Base.

  15. Horonobe underground research program. Research report of 2002 FY investigation

    International Nuclear Information System (INIS)

    Main results of investigation about Horonobe deep underground research center in 2002 FY were reported. It consists of six chapters: introduction, main results, selection of research center area, underground science research, R and D of geological disposal, and the environmental survey and research center on the ground. The research center area at about 3 km north of Horonobe (B1) was selected in the four areas: A, B1, B2 and C on the basis of data, researches in the sky, aboveground and underground and other conditions. The model of geological environment was constructed by physical, geological, surface water supply researches. Development of geological environment monitoring techniques, investigation of long stabilization of geological environment and design of underground facilities are reported. The basic design of preparation of research center was investigated. (S.Y.)

  16. ORGDP RCRA facility investigation program: plans and content

    International Nuclear Information System (INIS)

    Preparation of RCRA Facility Investigation (RFI) plans for thirty four 3004(u) sites at the ORGDP will be accomplished during FY-87 and FY-88. The plans will be written to guide the sampling and analyses of the sites to determine the extent, if any, of contamination. This investigation will then be the cornerstone for design of corrective measures for site remediation. The RFI plans at the ORGDP are being prepared by two Martin Marietta Energy Systems, Inc., project teams. The organization of the teams, the schedules, and the costs associated with preparation of the documents will be discussed. The contents of the general RFI plan document and a typical site-specific plan will be shown and the contents and methodology of each section will be highlighted

  17. TC-Investigator: A Matlab Program to Explore Pseudosections

    Science.gov (United States)

    Pearce, Mark; Gazley, Michael; White, Alistair

    2014-05-01

    Forward modelling of bulk rock compositions to constrain pressures and temperatures of metamorphism based on mineral assemblage is a commonly used technique. The pseudosections produced contain a wealth of information about predicted mineral compositions and abundances that goes far beyond variations in mineral assemblage. A grid of these variations can be contoured using Gibbs free energy minimisation software (such as Theriak-Domino) or precise isopleths calculated for specific quantities in THERMOCALC. We have produced a new piece of software called TC-Investigator that amalgamates these approaches to provide a relatively quick and user friendly way to contour all compositional parameters and mineral modes across a THERMOCALC pseudosection. TC-Investigator takes the postscript pseudosection diagram and creates a grid of points at a user-specified resolution. THERMOCALC is then used to calculate the equilibrium mineral assemblage at each point using an initial starting guess provided by the user (this can be calculated during initial pseudosection calculation). Once all points have been tried, any that failed to calculate are re-tried using interpolated starting guess values from the surrounding points. This procedure is iterated until no more solutions are found. Any remaining unsolved points are then interpolated numerically from surrounding solutions to produce a fully quantified set of mineral modes and compositions. Following calculation, the dataset can be contoured and output as figures, output as a Matlab readable binary structure or selected compositions written to an ASCII text file. Compositional maps created by TC-Investigator have the power to inform the user about compositional variables that are not conventionally considered. The automated calculation method makes it easy to investigate all variables in one go. For example, in metapelitic rocks, garnet shows the variations in composition that are usually contoured, however, these couple to

  18. 48 CFR 1852.219-83 - Limitation of the principal investigator-SBIR program.

    Science.gov (United States)

    2010-10-01

    ... investigator-SBIR program. 1852.219-83 Section 1852.219-83 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.219-83 Limitation of the principal investigator—SBIR program. As prescribed in 1819.7302(d), insert the following clause: Limitation of the Principal Investigator—SBIR Program...

  19. 48 CFR 1852.219-84 - Limitation of the principal investigator-STTR program.

    Science.gov (United States)

    2010-10-01

    ... investigator-STTR program. 1852.219-84 Section 1852.219-84 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.219-84 Limitation of the principal investigator—STTR program. As prescribed in 1819.7302(e), insert the following clause: Limitation of the Principal Investigator—STTR Program...

  20. A Survey of Successful Evaluations of Program Visualization and Algorithm Animation Systems

    Science.gov (United States)

    Urquiza-Fuentes, Jaime; Velazquez-Iturbide, J. Angel

    2009-01-01

    This article reviews successful educational experiences in using program and algorithm visualizations (PAVs). First, we survey a total of 18 PAV systems that were subject to 33 evaluations. We found that half of the systems have only been tested for usability, and those were shallow inspections. The rest were evaluated with respect to their…

  1. Project EAGLE (Early Academic Gifted Learning Experience): A Program for Gifted and Talented Students (Grades K-3)--Animals 3; Magnets; Sight; Geoboards 3; Dinosaurs 3; and Groups 3.

    Science.gov (United States)

    Merkoski, Kay

    Six thematic activity booklets are presented for implementing Project EAGLE, an enrichment program for gifted and talented primary-level children. "Animals 3" introduces endangered animals and locates their home areas on maps or globes, using nine learning activities involving science and creative writing. "Magnets" discusses what magnets are and…

  2. Report to the Governor of Alaska on cooperative predatory-animal investigations and control in the Territory for the period March 1, 1929, to February 28, 1931

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a report to the governor of Alaska on cooperative predatory animal investigations and control in the territory for the period March 1, 1929 to...

  3. An investigation of scale effects in family substance abuse treatment programs

    OpenAIRE

    Lee A James

    2010-01-01

    Abstract This short report investigates scale effects in family substance abuse treatment programs. In Massachusetts, the family substance abuse treatment programs were much more costly than other adult residential treatment models. State officials were concerned that the "scale" or size of these programs (averaging just eight families) was too small to be economical. Although the sample size (just nine programs) was too small to permit reliable inference, the data clearly signalled the impor...

  4. Animal Assisted Therapy (AAT) Program As a Useful Adjunct to Conventional Psychosocial Rehabilitation for Patients with Schizophrenia: Results of a Small-scale Randomized Controlled Trial

    OpenAIRE

    Calvo, Paula; Fortuny, Joan R.; Guzmán, Sergio; Macías, Cristina; Bowen, Jonathan; García, María L.; Orejas, Olivia; Molins, Ferran; Tvarijonaviciute, Asta; Cerón, José J.; Bulbena, Antoni; Fatjó, Jaume

    2016-01-01

    Currently, one of the main objectives of human–animal interaction research is to demonstrate the benefits of animal assisted therapy (AAT) for specific profiles of patients or participants. The aim of this study is to assess the effect of an AAT program as an adjunct to a conventional 6–month psychosocial rehabilitation program for people with schizophrenia. Our hypothesis is that the inclusion of AAT into psychosocial rehabilitation would contribute positively to the impact of the overall pr...

  5. VILLAGE’S HERDS: INVESTIGATING THE INTRODUCTION OF DOMESTIC ANIMALS AND PATTERNS OF ANIMAL HUSBANDRY AMONG INDIGENOUS PEOPLES IN AMAZONIA (RONDÔNIA)

    OpenAIRE

    Felipe Ferreira Vander Velden

    2011-01-01

    This paper discuss the introduction of European domestic animals in indigenous villages in the Amazon, with particular stress on groups in Rondonia, specially the Karitiana, a Tupi-Arikém-speaking people that lives in the north of that state. In what concerns the history of Brazilian territorial conquest, marked by the ‘frentes pastoris’’ great narrative, and the present expansion – material and also ideological – of husbandry throughout Amazonia, this article points to many questions about t...

  6. An Evaluation of a Court-Mandated Batterer Intervention Program: Investigating Differential Program Effect for African American and White Women

    Science.gov (United States)

    Carney, Michelle Mohr; Buttell, Frederick P.

    2006-01-01

    Objective: The purpose of this study is to (a) evaluate a 16-week batterer intervention program by investigating changes in psychological variables related to abuse between pretreatment and posttreatment assessments in a sample of women involuntarily placed in treatment and (b) to investigate the differential effectiveness of this same batterer…

  7. Seismic investigations of the HDR Safety Program. Summary report

    Energy Technology Data Exchange (ETDEWEB)

    Malcher, L.; Schrammel, D. [Kernforschungszentrum Karlsruhe GmbH (Germany); Steinhilber, H. [Fraunhofer-Institut fuer Betriebsfestigkeit (LBF), Darmstadt (Germany); Kot, C.A. [Argonne National Lab., IL (United States)

    1994-08-01

    The primary objective of the seismic investigations, performed at the HDR facility in Kahl/Main, FRG was to validate calculational methods for the seismic evaluation of nuclear-reactor systems, using experimental data from an actual nuclear plant. Using eccentric mass shaker excitation the HDR soil/structure system was tested to incipient failure, exhibiting highly nonlinear response and demonstrating that structures not seismically designed can sustain loads equivalent to a design basin earthquake (DBE). Load transmission from the structure to piping/equipment indicated significant response amplifications and shifts to higher frequencies, while the response of tanks/vessels depended mainly on their support conditions. The evaluation of various piping support configurations demonstrated that proper system design (for a given spectrum) rather than number of supports or system stiffness is important to limiting pipe greens. Piping at loads exceeding the DBE eightfold still had significant margins and failure is improbable inspite of multiple support failures. The mean value for pipe damping, even under extreme loads, was found to be about 4%. Comparison of linear and nonlinear computational results with piping response measurements showed that predictions have a wide scatter and do not necessarily yield conservative responses underpredicting, in particular, peak support forces. For the soil/structure system the quality of the predictions did not depend so much on the complexity of the modeling, but rather on whether the model captured the salient features and nonlinearities of the system.

  8. Investigation on wild animal resource in Sunan and Subei counties%肃南肃北草原野生动物资源调查研究

    Institute of Scientific and Technical Information of China (English)

    赵忠; 王军; 张卫军; 郭金梅; 柴永青; 泽德; 那·巴特尔; 何毅; 杨鹏翼; 李青; 金赐福; 贾生福; 杨学兰; 孙晓云; 顾自林

    2011-01-01

    By 3-year investigation and study on wild animal resource in Sunan and Subei counties, the result indicated that the major wild terrestrial vertebrate on the grassland area in the Qilianshan Mountains and Mazongshah Mountains could be divided into 5 faunae, alpine desert animal fauna, alpine meadow animal faunal, desert animal fauna, marsh animal fauna and village-farmland animal faunal; More than 800 animal species embracing ungulate, carnivore, reptile, amphibian, fish, rodent, avifauna and insect were located in the area; Among the wild animals, 24 species were the national protective animal, accounting for 26 % of total wild animal and bird species in Sunan and Subei counties. Out of the protective animals, 10 species were the first class national protective animal; 24 species were the second class national protective animal.%通过对肃南、肃北草原野生动物资源3年的调查研究分析,结果表明,祁连山地及马鬃山区草原地带活动的主要陆生脊椎野生动物种群可划分为5个类群,高山寒漠动物群、高山草甸动物群、荒漠动物群、沼泽动物群和村庄农田动物群,有蹄类、食肉类、爬行类、两栖类、鱼类、啮齿类、鸟类及昆虫类约有800多种;国家级保护动物共有34种,占肃南、肃北鸟兽种数的26%.其中国家一级保护动物有10种;国家二级保护动物有24种.

  9. Learning Anime Studio

    CERN Document Server

    Troftgruben, Chad

    2014-01-01

    Anime Studio is your complete animation program to help you create 2D movies, cartoons, anime, and cut out animations. You can create your own animated shorts and use Anime Studio to produce cartoon animations for film, video, or streaming over the Web, which can be enjoyed on YouTube, Vimeo, and other popular sites. Anime Studio is great for hobbyists and professionals alike, combining tools for both illustration and animation. With Anime Studio's easy-to-use interface, you will be creating an animated masterpiece in no time. This practical, step-by-step guide will provide you with a structur

  10. Guest investigator program study: Physics of equatorial plasma bubbles

    Science.gov (United States)

    Tsunoda, Roland T.

    1994-01-01

    -shaped plasma bubbles. The second topic was pursued because the inability to predict the day-to-day occurrence of plasma bubbles indicated inadequate knowledge of the physics of plasma bubbles. An understanding of bubble formation requires an understanding of the roles of the various terms in the linearized growth rate of the collisional Rayleigh-Taylor instability. In our study, we examined electric-field perturbations found in SM-D EFI data and found that the seeding is more likely to be produced in the E region rather than the F region. The results of this investigation are presented in the Appendix of this report and will be submitted for publication in the Journal of Geophysical Research.

  11. Paws for a Study Break: Running an Animal-Assisted Therapy Program at the Gerstein Science Information Centre

    Directory of Open Access Journals (Sweden)

    Allison Bell

    2013-06-01

    Full Text Available The Gerstein Science Information Centre is the Science and Health Sciences library serving the University of Toronto community. As the second largest library on campus, Gerstein is a mecca for studying and can accommodate 1100 students. Research has shown that high levels of stress, anxiety, depression, and other mental health disorders are prevalent among both medical students and the student population as a whole. In recent years, Gerstein staff members have seen evidence of the rising levels of student stress in their dealings with the public while providing reference and research help. Animal-assisted therapy (AAT is often used in hospital and rehabilitation settings and, most recently, to help young children learn to read by providing a stress-free learning environment in public libraries and schools. Studies on animal-assisted therapy have shown that AAT decreases blood pressure, cortisol, and reduces anxiety overall. In response to these findings, staff at Gerstein decided to implement an AAT program, “Paws for a Study Break,” comprised of several sessions when a therapy dog and her handler would visit the library to hold ‘office hours’ and give students a break from their studying during the Winter 2012 exam period. Through a total of six visits of ninety minutes each, 417 visitors were received. Best practices and lessons learned are discussed, including steps involved in coordination of the event, working with volunteers, publicity avenues, dealing with media requests, costs involved, and evaluation techniques. Based on the completed evaluation forms, the response to the therapy dog program at Gerstein was overwhelmingly positive; students were very appreciative, and there are plans underway to repeat this program on an ongoing basis.

  12. Animated Asphalt

    DEFF Research Database (Denmark)

    Paldam, Camilla Skovbjerg

    2015-01-01

    “animation”, defined as “an innate (and learnable) ability of our bodies to discover life in inanimate images” (Belting 2012, 188). In this essay I investigate the animation of pictures in dialogue with Mitchell, both by addressing general questions such as: how is animation of otherwise static pictures...... to be understood? How does animation differ in different media? And in particular by focusing on and questioning the gender positions inherent in Mitchell’s theory. Animation has an erotic component of seduction and desire, and what pictures want, becomes for Mitchell, what women want. There is of course no simple...

  13. The application of medical informatics to the veterinary management programs at companion animal practices in Alberta, Canada: a case study.

    Science.gov (United States)

    Anholt, R M; Berezowski, J; Maclean, K; Russell, M L; Jamal, I; Stephen, C

    2014-02-01

    Companion animals closely share their domestic environment with people and have the potential to, act as sources of zoonotic diseases. They also have the potential to be sentinels of infectious and noninfectious, diseases. With the exception of rabies, there has been minimal ongoing surveillance of, companion animals in Canada. We developed customized data extraction software, the University of, Calgary Data Extraction Program (UCDEP), to automatically extract and warehouse the electronic, medical records (EMR) from participating private veterinary practices to make them available for, disease surveillance and knowledge creation for evidence-based practice. It was not possible to build, generic data extraction software; the UCDEP required customization to meet the specific software, capabilities of the veterinary practices. The UCDEP, tailored to the participating veterinary practices', management software, was capable of extracting data from the EMR with greater than 99%, completeness and accuracy. The experiences of the people developing and using the UCDEP and the, quality of the extracted data were evaluated. The electronic medical record data stored in the data, warehouse may be a valuable resource for surveillance and evidence-based medical research.

  14. Lessons Learned from the First Two Years of Nature's Notebook, the USA National Phenology Network's Plant and Animal Observation Program

    Science.gov (United States)

    Crimmins, T. M.; Rosemartin, A.; Denny, E. G.; Weltzin, J. F.; Marsh, L.

    2010-12-01

    Nature’s Notebook is the USA National Phenology Network’s (USA-NPN) national-scale plant and animal phenology observation program. The program was launched in March 2009 focusing only on plants; 2010 saw the addition of animals and the name and identity “Nature’s Notebook.” Over these two years, we have learned much about how to effectively recruit, train, and retain participants. We have engaged several thousand participants and can report a retention rate, reflected in the number of registered individuals that report observations, of approximately 25%. In 2009, participants reported observations on 133 species of plants on an average of nine days of the year, resulting in over 151,000 records in the USA-NPN phenology database. Results for the 2010 growing season are still being reported. Some of our most valuable lessons learned have been gleaned from communications with our observers. Through an informal survey, participants indicated that they would like to see more regular and consistent communications from USA-NPN program staff; clear, concise, and readily available training materials; mechanisms to keep them engaged and continuing to participate; and quick turn-around on data summaries. We are using this feedback to shape our program into the future. Another key observation we’ve made about our program is the value of locally and regionally-based efforts to implement Nature’s Notebook; some of our most committed observers are participating through partner programs such as the University of California-Santa Barbara Phenology Stewardship Program, Arbor Day Foundation, and the Great Sunflower Project. Future plans include reaching out to more partner organizations and improving our support for locally-based implementations of the Nature’s Notebook program. We have also recognized that the means for reaching and retaining potential participants in Nature’s Notebook vary greatly across generations. As the majority of our participants to

  15. An Investigation of the Effects of Different Types of Activities during Pauses in a Segmented Instructional Animation

    Science.gov (United States)

    Cheon, Jongpil; Chung, Sungwon; Crooks, Steven M.; Song, Jaeki; Kim, Jeakyeong

    2014-01-01

    Since the complex and transient information in instructional animations requires more cognitive resources, the segmenting principle has been proposed to reduce cognitive overload by providing smaller chunks with pauses between segments. This study examined the effects of different types of activities during pauses in a segmented animation. Four…

  16. Empirical Investigation into Motives for Choosing Web-Based Distance Learning Programs

    Science.gov (United States)

    Alkhattabi, Mona

    2016-01-01

    Today, in association with rapid social and economic changes, there is an increasing level of demand for distance and online learning programs. This study will focus on identifying the main motivational factors for choosing a web-based distance-learning program. Moreover, it will investigate how these factors relate to age, gender, marital status…

  17. 78 FR 79567 - Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations

    Science.gov (United States)

    2013-12-31

    ...: The ICR associated with the rule published in the Federal Register on August 21, 2013, at 78 FR 51649... Program: Trafficking Controls and Fraud Investigations AGENCY: Food and Nutrition Service, USDA. ACTION... rule entitled Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud...

  18. 78 FR 51649 - Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations

    Science.gov (United States)

    2013-08-21

    ... burden for States overall. The proposed rule was published on May 30, 2012, at 77 FR 31738, and public... Assistance Program--Food Distribution Program on Indian Reservations Dual Participation, 78 FR 11967 (Feb. 21... Controls and Fraud Investigations AGENCY: Food and Nutrition Service (FNS), USDA. ACTION: Final...

  19. Investigation of Effect of Nutritional Drink on Chemotherapy-Induced Mucosal Injury and Tumor Growth in an Established Animal Model

    Directory of Open Access Journals (Sweden)

    Eduardo Schiffrin

    2013-09-01

    Full Text Available Chemotherapy-induced mucositis represents a significant burden to quality of life and healthcare costs, and may be improved through enhanced nutritional status. We first determined the safety of two nutritional drinks (plus placebo, and then potential gut protection in tumor-bearing rats in a model of methotrexate-induced mucositis. In study 1, animals were fed one of two test diets (or placebo or control chow pellets for a total of 60 days and were monitored daily. All diets were found to be safe to administer. In study 2, after seven days of receiving diets, a Dark Agouti Mammary Adenocarcinoma (DAMA was transplanted subcutaneously. Ten days after starting diets, animals had 2 mg/kg intramuscular methotrexate administered on two consecutive days; after this time, all animals were given soaked chow. Animals were monitored daily for changes in bodyweight, tumor burden and general health. Animals were killed 10, 12 and 16 days after initially starting diets, and tissues were collected at necropsy. In study 1, animals receiving diets had gained 0.8% and 10.8% of their starting bodyweight after 60 days, placebo animals 4.4%, and animals fed on standard chow had gained 15.1%. In study 2, there was no significant influence of test diet on bodyweight, organ weight, tumor burden or biochemical parameters. Only animals treated with MTX exhibited diarrhea, although animals receiving Diet A and Diet C showed a non-significant increase in incidence of diarrhea. Administration of these nutritional drinks did not improve symptoms of mucositis.

  20. Investigation of effect of nutritional drink on chemotherapy-induced mucosal injury and tumor growth in an established animal model.

    Science.gov (United States)

    Bateman, Emma; Bowen, Joanne; Stringer, Andrea; Mayo, Bronwen; Plews, Erin; Wignall, Anthony; Greenberg, Norman; Schiffrin, Eduardo; Keefe, Dorothy

    2013-09-30

    Chemotherapy-induced mucositis represents a significant burden to quality of life and healthcare costs, and may be improved through enhanced nutritional status. We first determined the safety of two nutritional drinks (plus placebo), and then potential gut protection in tumor-bearing rats in a model of methotrexate-induced mucositis. In study 1, animals were fed one of two test diets (or placebo or control chow pellets) for a total of 60 days and were monitored daily. All diets were found to be safe to administer. In study 2, after seven days of receiving diets, a Dark Agouti Mammary Adenocarcinoma (DAMA) was transplanted subcutaneously. Ten days after starting diets, animals had 2 mg/kg intramuscular methotrexate administered on two consecutive days; after this time, all animals were given soaked chow. Animals were monitored daily for changes in bodyweight, tumor burden and general health. Animals were killed 10, 12 and 16 days after initially starting diets, and tissues were collected at necropsy. In study 1, animals receiving diets had gained 0.8% and 10.8% of their starting bodyweight after 60 days, placebo animals 4.4%, and animals fed on standard chow had gained 15.1%. In study 2, there was no significant influence of test diet on bodyweight, organ weight, tumor burden or biochemical parameters. Only animals treated with MTX exhibited diarrhea, although animals receiving Diet A and Diet C showed a non-significant increase in incidence of diarrhea. Administration of these nutritional drinks did not improve symptoms of mucositis.

  1. An investigation of scale effects in family substance abuse treatment programs

    Directory of Open Access Journals (Sweden)

    Lee A James

    2010-07-01

    Full Text Available Abstract This short report investigates scale effects in family substance abuse treatment programs. In Massachusetts, the family substance abuse treatment programs were much more costly than other adult residential treatment models. State officials were concerned that the "scale" or size of these programs (averaging just eight families was too small to be economical. Although the sample size (just nine programs was too small to permit reliable inference, the data clearly signalled the importance of "scale effects" in these family substance abuse treatment programs. To further investigate scale effects in family substance abuse treatment programs, data from the Center for Substance Abuse Treatment's (CSAT's Residential Women and Children and Pregnant and Postpartum Women (RWC-PPW Demonstration were re-analyzed, focusing on the relationship between cost per family-day and the estimated average family census. This analysis indicates strong economies of scale up until an average family census of about 14, and less apparent scale effects beyond that point. In consideration of these and other study findings, a multidisciplinary interagency team redesigned the Massachusetts' family treatment program model. The new programs are larger than the former family treatment programs, with each new program having capacity to treat 11 to 15 families depending on family makeup.

  2. Programming the brain: Common outcomes and gaps in knowledge from animal studies of IUGR.

    Science.gov (United States)

    Hunter, Damien S; Hazel, Susan J; Kind, Karen L; Owens, Julie A; Pitcher, Julia B; Gatford, Kathryn L

    2016-10-01

    IUGR in humans is associated with impaired pre- and postnatal neurodevelopment, and subsequent postnatal cognition, resulting in lower IQ, poorer memory, visuomotor and executive function skills, as well as behavioural and attentional problems. Experimental models of IUGR are needed to allow direct testing of causality and interventions, and have benefits in reducing both confounding by comorbidities such as prematurity, and variation due to environment and genetics. This review describes and discusses experimental models of IUGR in which neurodevelopmental and cognitive outcomes of IUGR have been reported. We consider the timing of neurodevelopment relative to birth and to the period of restriction, as well as the effects of each experimental perturbation on the fetal environment and development, before discussing neurodevelopmental and cognitive outcomes for progeny as fetuses, neonates and into adolescent and adult life. Experimental IUGR induces broadly similar outcomes to human IUGR, with altered brain morphology, in particular grey matter loss and discordant trajectory of white matter development, and poorer cognition and memory reported in various studies. Nevertheless, there remain gaps in knowledge of neurodevelopment in experimental models. We end the review with recommendations for the design of future studies to further investigate the mechanisms underlying adverse neurodevelopmental consequences of IUGR, and to evaluate interventions that may subsequently improve outcomes of IUGR in humans.

  3. Programming the brain: Common outcomes and gaps in knowledge from animal studies of IUGR.

    Science.gov (United States)

    Hunter, Damien S; Hazel, Susan J; Kind, Karen L; Owens, Julie A; Pitcher, Julia B; Gatford, Kathryn L

    2016-10-01

    IUGR in humans is associated with impaired pre- and postnatal neurodevelopment, and subsequent postnatal cognition, resulting in lower IQ, poorer memory, visuomotor and executive function skills, as well as behavioural and attentional problems. Experimental models of IUGR are needed to allow direct testing of causality and interventions, and have benefits in reducing both confounding by comorbidities such as prematurity, and variation due to environment and genetics. This review describes and discusses experimental models of IUGR in which neurodevelopmental and cognitive outcomes of IUGR have been reported. We consider the timing of neurodevelopment relative to birth and to the period of restriction, as well as the effects of each experimental perturbation on the fetal environment and development, before discussing neurodevelopmental and cognitive outcomes for progeny as fetuses, neonates and into adolescent and adult life. Experimental IUGR induces broadly similar outcomes to human IUGR, with altered brain morphology, in particular grey matter loss and discordant trajectory of white matter development, and poorer cognition and memory reported in various studies. Nevertheless, there remain gaps in knowledge of neurodevelopment in experimental models. We end the review with recommendations for the design of future studies to further investigate the mechanisms underlying adverse neurodevelopmental consequences of IUGR, and to evaluate interventions that may subsequently improve outcomes of IUGR in humans. PMID:27288225

  4. Images of Animals: Interpreting Three-Dimensional, Life-Sized 'Representations' of Animals--Zoo, Museum and Robotic Animals.

    Science.gov (United States)

    Tunnicliffe, Sue Dale

    A visit to the natural history museum is part of many pupils' educational program. One way of investigating what children learn about animals is to examine the mental models they reveal through their talk when they come face to face with animal representations. In this study, representations were provided by: (1) robotic models in a museum; (2)…

  5. Physics for Animation Artists

    Science.gov (United States)

    Chai, David; Garcia, Alejandro L.

    2011-01-01

    Animation has become enormously popular in feature films, television, and video games. Art departments and film schools at universities as well as animation programs at high schools have expanded in recent years to meet the growing demands for animation artists. Professional animators identify the technological facet as the most rapidly advancing…

  6. A Study to Investigate Learning A Style That Has Higher Grade Achievement In Computer Programming

    OpenAIRE

    Yeboah, Dr. Thomas; Sarpong, Appiah

    2012-01-01

    Some students perform extremely excellent in some courses whiles they performance poorly in computer programming couse in most of the Ghanaian higher institutions. The question is why some students perform excellent in some courses but these same students perform poorly in computer programming course.In looking for ways of addressing this question the study seek to investigate whether some students with particular learning styles are likely to perform better than others. During the study the ...

  7. Investigating conditions for transfer of learning in an outdoor experiential study abroad program

    OpenAIRE

    Anderson, Michael Laden

    2006-01-01

    The purpose of the study was to investigate how teaching for transfer of learning was built into a month-long outdoor experiential education course within a semester long study abroad program and to address the extent to which student perception of learning gains could be transferred for use in future courses and for later in life. From a program planning and evaluation perspective it was also important to determine what types of activities and experiences within the course were instrumental ...

  8. Animals in biomedical space research

    Science.gov (United States)

    Phillips, R. W.

    1986-01-01

    Rat and squirrel monkeys experiments have been planned in concert with human experiments to help answer fundamental questions concerning the effect of weightlessness on mammalism function. For the most part, these experiments focus on identified changes noted in humans during space flight. Utilizing space laboratory facilities, manipulative experiments can be completed while animals are still in orbit. Other experiments are designed to study changes in gravity receptor structure and function and the effect of weightlessness on early vertibrate development. Following these preliminary animal experiments on Spacelab Shuttle flights, longer term programs of animal investigation will be conducted on Space Station.

  9. Bone scintigraphy for the investigation of lameness in small animals; Einsatz der Skelettszintigrafie in der Lahmheitsdiagnostik beim Kleintier

    Energy Technology Data Exchange (ETDEWEB)

    Bolln, G.; Franke, C. [Tieraerztliche Klinik fuer Kleintiere, Norderstedt (Germany)

    2010-03-15

    Bone scintigraphy has been used as a helpful method in diagnosing lameness in small animals. It is a sensitive, non-invasive method to evaluate bone lesions and orthopaedic disorders. It provides a functional image of the skeleton and thereby aiding in the localisation and diagnosing of obscure lameness. Compared to human medicine one important difference is the inability of an animal to characterize its pain to the examiner. Another difference is the lacking cooperation of an animal during bone scintigraphy. Before this background are shown on the basis of 5 examples the advantages, the method and the different indication of bone scintigraphy. The technique of this method arrives from a human medicine protocol of a 2-phase-bone-scintigraphy and has to be done under light anaesthesia, to avoid artefacts of movement during acquisitions. The authors are convinced that bone scintigraphy is a very useful and diagnostic method for evaluation of obscure lameness because it can give a quick diagnosis and aimed therapy. Therefore secondary changes and additional costs can be avoided for the animal and its owner. (orig.)

  10. Investigating bias in the application of curve fitting programs to atmospheric time series

    Directory of Open Access Journals (Sweden)

    P. A. Pickers

    2014-07-01

    Full Text Available The decomposition of an atmospheric time series into its constituent parts is an essential tool for identifying and isolating variations of interest from a data set, and is widely used to obtain information about sources, sinks and trends in climatically important gases. Such procedures involve fitting appropriate mathematical functions to the data, however, it has been demonstrated that the application of such curve fitting procedures can introduce bias, and thus influence the scientific interpretation of the data sets. We investigate the potential for bias associated with the application of three curve fitting programs, known as HPspline, CCGCRV and STL, using CO2, CH4 and O3 data from three atmospheric monitoring field stations. These three curve fitting programs are widely used within the greenhouse gas measurement community to analyse atmospheric time series, but have not previously been compared extensively. The programs were rigorously tested for their ability to accurately represent the salient features of atmospheric time series, their ability to cope with outliers and gaps in the data, and for sensitivity to the values used for the input parameters needed for each program. We find that the programs can produce significantly different curve fits, and these curve fits can be dependent on the input parameters selected. There are notable differences between the results produced by the three programs for many of the decomposed components of the time series, such as the representation of seasonal cycle characteristics and the long-term growth rate. The programs also vary significantly in their response to gaps and outliers in the time series. Overall, we found that none of the three programs were superior, and that each program had its strengths and weaknesses. Thus, we provide a list of recommendations on the appropriate use of these three curve fitting programs for certain types of data sets, and for certain types of analyses and

  11. Animal learning.

    Science.gov (United States)

    Castro, Leyre; Wasserman, Edward A

    2010-01-01

    Pavlov and Thorndike pioneered the experimental study of animal learning and provided psychologists with powerful tools to unveil its underlying mechanisms. Today's research developments and theoretical analyses owe much to the pioneering work of these early investigators. Nevertheless, in the evolution of our knowledge about animal learning, some initial conceptions have been challenged and revised. We first review the original experimental procedures and findings of Pavlov and Thorndike. Next, we discuss critical research and consequent controversies which have greatly shaped animal learning theory. For example, although contiguity seemed to be the only condition that is necessary for learning, we now know that it is not sufficient; the conditioned stimulus (CS) also has to provide information about the occurrence of the unconditioned stimulus (US). Also, animals appear to learn different things about the same stimuli when circumstances vary. For instance, when faced with situations in which the meaning of a CS changes, as in the case of acquisition and later extinction, animals seem to preserve the original knowledge (CS-US) in addition to learning about the new conditions (CS-noUS). Finally, we discuss how parallels among Pavlovian conditioning, operant conditioning, and human causal judgment suggest that causal knowledge may lie at the root of both human and animal learning. All of these empirical findings and theoretical developments prove that animal learning is more complex and intricate than was once imagined. Copyright © 2009 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website. PMID:26272842

  12. Student Planetary Investigators: A Program to Engage Students in Authentic Research Using NASA Mission Data

    Science.gov (United States)

    Hallau, K.; Turney, D.; Beisser, K.; Edmonds, J.; Grigsby, B.

    2015-12-01

    The Student Planetary Investigator (PI) Program engages students in authentic scientific research using NASA mission data. This student-focused STEM (Science, Technology, Engineering and Math) program combines problem-based learning modules, Next Generation Science Standards (NGSS) aligned curriculum, and live interactive webinars with mission scientists to create authentic research opportunities and career-ready experiences that prepare and inspire students to pursue STEM occupations. Primarily for high school students, the program employs distance-learning technologies to stream live presentations from mission scientists, archive those presentations to accommodate varied schedules, and collaborate with other student teams and scientists. Like its predecessor, the Mars Exploration Student Data Team (MESDT) program, the Student PI is free and open to teams across the country. To date, students have drafted research-based reports using data from the Lunar Reconnaissance Orbiter Mini-RF instrument and the MESSENGER Mercury orbiter, with plans to offer similar programs aligned with additional NASA missions in the future pending available funding. Overall, the program has reached about 600 students and their educators. Assessments based on qualitative and quantitative data gathered for each Student PI program have shown that students gain new understanding about the scientific process used by real-world scientists as well as gaining enthusiasm for STEM. Additionally, it is highly adaptable to other disciplines and fields. The Student PI program was created by the Johns Hopkins University Applied Physics Laboratory (APL) Space Department Education and Public Outreach office with support from NASA mission and instrument science and engineering teams.

  13. [The investigation into specific features of the distribution of carbofuran in the body of the warm-blooded animals].

    Science.gov (United States)

    Shormanov, V K; Galushkin, S G; Kovalenko, E A; Terskikh, A P

    2015-01-01

    The objective of the present study was to estimate the distribution of the carbamate pesticide carfbofuran in the organism of the warm-blooded animals (rats) after its intragastric administration. It was shown that large amounts of unmetabolized carbofuran were present in the internal organs and biological fluids. The highest content of carbofuran was recorded in the stomach, large and small intestines, testicles, urinary bladder, ureters, and heart.

  14. Myelin Abnormalities in Schizophrenia: Insights from Proteomic Investigations of Post-Mortem Schizophrenia and Pre-Clinical Animal Models

    OpenAIRE

    Farrelly, Lorna

    2014-01-01

    Accumulating evidence from epidemiologic and clinical findings report that both exposure to prenatal inflammation and prenatal iron deficiency significantly increase the risk of developing Schizophrenia in the offspring. Abnormalities in myelin are the most robust neuropathological findings in post-mortem human Schizophrenia, however the exact mechanisms at the protein and pathway levels owing to the myelin deficits are largely unknown. Animal models offer a fruitful approach to study the ...

  15. Exploratory investigation of the need for and feasibility of a Lower Atmosphere Research Satellite (LARS) program

    Science.gov (United States)

    1980-01-01

    The need for and feasibility of a research satellite program for the intensive study of the lower atmosphere (the troposphere and lower stratosphere) is discussed. The priorities for scientific investigation of the lower atmosphere during the next decade are examined. The findings of the study are concerned with identification of those broad research issues of highest priority and, in particular, with those that are most appropriate for investigation from space platforms.

  16. Investigating the Relationship between Iranian EFL Teachers' Autonomy and Their Neuro-Linguistic Programming

    Science.gov (United States)

    Hosseinzadeh, Ehsan; Baradaran, Abdollah

    2015-01-01

    The present study was an attempt to investigate the relationship between English Language Teachers' autonomy and their Neuro-linguistic Programming (NLP). To this end, a group of 200 experienced English language teachers at various language schools in Tehran, inter alia, Asre Zaban Language Academy, were given two questionnaires namely Teaching…

  17. 76 FR 55332 - Federal Bureau of Investigation Anti-Piracy Warning Seal Program

    Science.gov (United States)

    2011-09-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE 41 CFR Part 128-1 RIN 1110-AA32 Federal Bureau of Investigation Anti-Piracy Warning Seal Program AGENCY...- Piracy Warning Seal (APW Seal). The proposed rule will provide access to the APW Seal to all...

  18. Satellite Power System Concept Development and Evaluation Program, Critical Supporting Investigations. Summary

    Science.gov (United States)

    Seyl, J. W.

    1980-01-01

    Investigations in critical technology of the solar power satellite (SPS) concept development program are summarized. Studies of the potential application of fiber optics transmission links across the SPS one kilometer antenna and evaluation of gallium arsenide field effect transistors and their associated power amplifier circuitry are discussed in more detail.

  19. Blended Learning: Investigating Its Potential in an English Language Teacher Training Program

    Science.gov (United States)

    Kocoglu, Zeynep; Ozek, Yesim; Kesli, Yesim

    2011-01-01

    Although the benefits of blended learning have been well documented in educational research, relatively few studies have examined blended learning in language teacher education. This study discusses a blended learning approach for a teacher training program designed for in-service English language teachers, and investigates its effectiveness by…

  20. INVESTIGATING THE OPINIONS OF MoNE STAFF ABOUT INSET PROGRAMS VIA DISTANCE EDUCATION

    Directory of Open Access Journals (Sweden)

    Rasit OZEN

    2009-10-01

    Full Text Available The aim of this study is to investigate the opinions of the Ministry of National Education (MoNE staff about in-service training (INSET programs via distance education. The subjects of this study were the staff (n=15 of the Inservice Training Department of MoNE in 2008. During the study, the qualitative data were collected through semi-structured interviews held with the (MoNE staff by the researcher. The results of the interviews revealed the importance of needs assessment, the relationship between INSET program course content and participants’ school curriculum, support mechanism in INSET programs via distance education, the application of what is learned and providing various opportunities to them that lead to their active involvement to the application of these programs, the characteristics of learning environments for these programs, INSET instructors’ teaching competencies and skills to fulfill various roles in online learning environments, of measuring and evaluating the performance of teachers during INSET programs via distance education and of the effectiveness of INSET programs via distance education.

  1. Investigating audiences’ attitudes towards local radio programs: A case study of city of Esfahan

    Directory of Open Access Journals (Sweden)

    Faezeh Taghipour

    2013-02-01

    Full Text Available For almost a century, radio stations have been some primary sources for presenting arts, entertainment, news, etc. and the primary concern on many studies is to understand audience attitude on this media. This paper attempts to investigate audience attitude on radio programs broadcasted in city of Esfahan, Iran. The proposed study selects random sample of 600 out of 1,745,428 residence of this city where 345 people actively were listening to these programs, actively. All questions were designed in Likert scale and Cronbach alpha was 0.941, which was well above the desirable level and validated the survey. According our survey, the most popular part of radio programs was associated with news where 78.3% of the audiences were listening to these programs. According to our survey, audiences were mostly satisfied with family oriented programs and the mean score was 4.05. The other observation indicates that people have good attitude towards educational guidance programs (mean=3.37 and programs related to people and officials (mean=3.41. The results of Freedman test with Chi-Square value of 52.507 determines that there is meaningful difference among different components (mean difference = -0.23 and P-value =0.022. We have also performed an investigation to find out whether there is any difference between different components of this survey in terms of participants’ personal characteristics such as age, gender, educational background and job. Our survey only confirms the mean difference in terms of job specifications and other personal characteristics did not have any impact on people’s attitude. The other observation in our survey indicates that there is a difference between students and people with no job or housekeeper on their attitudes towards educational programs.

  2. Evaluation of a Communication Skills Training Program for Companion-Animal Veterinarians: A Pilot Study Using RIAS Coding.

    Science.gov (United States)

    McArthur, Michelle; Fitzgerald, Jennifer

    2016-01-01

    Effective veterinarian communication skills training and the related key outcomes provided the impetus for this study. We implemented a pre-experimental pre-test/post-test single-group design with a sample of 13 veterinarians and their 71 clients to evaluate the effects of a 6.5-hour communication skills intervention for veterinarians. Consultations were audiotaped and analyzed with the Roter Interaction Analysis System (RIAS). Clients completed the Consultation and Relational Care Measure, a global satisfaction scale, a Parent Medical Interview Satisfaction Scale, and the Adherence Intent measure. Veterinarians completed a communication confidence measure and a workshop satisfaction scale. Contrary to expectation, neither veterinarian communication skills nor their confidence improved post-training. Despite client satisfaction and perceptions of veterinarians' relational communication skills not increasing, clients nevertheless reported an increased intent to adhere to veterinarian recommendations. This result is important because client adherence is critical to managing and enhancing the health and well-being of animals. The results of the study suggest that while the workshop was highly regarded, either the duration of the training or practice opportunities were insufficient or a booster session was required to increase veterinarian confidence and integration of new skills. Future research should utilize a randomized control study design to investigate the appropriate intervention with which to achieve change in veterinarian communication skills. Such change could translate to more effective interactions in veterinarians' daily lives. PMID:26966985

  3. Evaluation of a Communication Skills Training Program for Companion-Animal Veterinarians: A Pilot Study Using RIAS Coding.

    Science.gov (United States)

    McArthur, Michelle; Fitzgerald, Jennifer

    2016-01-01

    Effective veterinarian communication skills training and the related key outcomes provided the impetus for this study. We implemented a pre-experimental pre-test/post-test single-group design with a sample of 13 veterinarians and their 71 clients to evaluate the effects of a 6.5-hour communication skills intervention for veterinarians. Consultations were audiotaped and analyzed with the Roter Interaction Analysis System (RIAS). Clients completed the Consultation and Relational Care Measure, a global satisfaction scale, a Parent Medical Interview Satisfaction Scale, and the Adherence Intent measure. Veterinarians completed a communication confidence measure and a workshop satisfaction scale. Contrary to expectation, neither veterinarian communication skills nor their confidence improved post-training. Despite client satisfaction and perceptions of veterinarians' relational communication skills not increasing, clients nevertheless reported an increased intent to adhere to veterinarian recommendations. This result is important because client adherence is critical to managing and enhancing the health and well-being of animals. The results of the study suggest that while the workshop was highly regarded, either the duration of the training or practice opportunities were insufficient or a booster session was required to increase veterinarian confidence and integration of new skills. Future research should utilize a randomized control study design to investigate the appropriate intervention with which to achieve change in veterinarian communication skills. Such change could translate to more effective interactions in veterinarians' daily lives.

  4. Does glimepiride alter the pharmacokinetics of sildenafil citrate in diabetic nephropathy animals: investigating mechanism of interaction by molecular modeling studies.

    Science.gov (United States)

    Tripathi, Alok Shiomurti; Timiri, Ajay Kumar; Mazumder, Papiya Mitra; Chandewar, Anil

    2015-10-01

    The present study evaluates possible drug interactions between glimepiride (GLIM) and sildenafil citrate (SIL) in streptozotocin (STZ)-induced diabetic nephropathic (DN) animals and also postulates the possible mechanism of interaction based on molecular modeling studies. Diabetic nephropathy was induced by single dose of STZ (60 mg kg(-1), i.p.) and was confirmed by assessing blood and urine biochemical parameters 28 days after induction. Selected DN animals were used to explore the drug interaction between GLIM (0.5 mg kg(-1), p.o.) and SIL (2.5 mg kg(-1), p.o.) on the 29th and 70th day of the protocol. Possible drug interaction was assessed by evaluating the plasma drug concentration using HPLC-UV and changes in biochemical parameters in blood and urine were also determined. The mechanism of the interaction was postulated from the results of a molecular modeling study using the Maestro module of Schrodinger software. DN was confirmed as there was significant alteration in blood and urine biochemical parameters in STZ-treated groups. The concentration of SIL increased significantly (P < 0.001) in rat plasma when co-administered with GLIM on the 70th day of the protocol. Molecular modeling revealed important interactions with rat serum albumin and CYP2C9. GLIM has a strong hydrophobic interaction with binding site residues of rat serum albumin compared to SIL, whereas for CYP2C9, GLIM forms a stronger hydrogen bond than SIL with polar contacts and hydrophobic interactions. The present study concludes that bioavailability of SIL increases when co-administered chronically with GLIM in the management of DN animals, and the mechanism is supported by molecular modeling studies. PMID:26428531

  5. Investigation of integrons/cassettes in antimicrobial-resistant Escherichia coli isolated from food animals in China

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this study,326 Escherichia coli isolates from food animals collected during the last four decades in China were characterized using antimicrobial susceptibility testing and screening for integrons/cassettes.Minimum inhibitory concentration(MIC) testing indicated that the antimicrobial resistance of E.coli has increased since the 1970s.The findings of this study present a warning to veterinary practitioners about the excessive use of antimicrobials,and suggest the necessity for surveillance and control of antimicrobial resistance in veterinary clinical medicine in China.

  6. Investigation on natural diets of larval marine animals using peptide nucleic acid-directed polymerase chain reaction clamping.

    Science.gov (United States)

    Chow, Seinen; Suzuki, Sayaka; Matsunaga, Tadashi; Lavery, Shane; Jeffs, Andrew; Takeyama, Haruko

    2011-04-01

    The stomach contents of the larvae of marine animals are usually very small in quantity and amorphous, especially in invertebrates, making morphological methods of identification very difficult. Nucleotide sequence analysis using polymerase chain reaction (PCR) is a likely approach, but the large quantity of larval (host) DNA present may mask subtle signals from the prey genome. We have adopted peptide nucleic acid (PNA)-directed PCR clamping to selectively inhibit amplification of host DNA for this purpose. The Japanese spiny lobster (Panulirus japonicus) and eel (Anguilla japonica) were used as model host and prey organisms, respectively. A lobster-specific PNA oligomer (20 bases) was designed to anneal to the sequence at the junction of the 18 S rDNA gene and the internal transcribed spacer 1 (ITS1) of the lobster. PCR using eukaryote universal primers for amplifying the ITS1 region used in conjunction with the lobster-specific PNA on a mixed DNA template of lobster and eel demonstrated successful inhibition of lobster ITS1 amplification while allowing efficient amplification of eel ITS1. This method was then applied to wild-caught lobster larvae of P. japonicus and P. longipes bispinosus collected around Ryukyu Archipelago, Japan. ITS1 sequences of a wide variety of animals (Ctenophora, Cnidaria, Crustacea, Teleostei, Mollusca, and Chaetognatha) were detected. PMID:20535520

  7. [Investigation of pathogenic phenotypes and virulence determinants of food-borne Salmonella enterica strains in Caenorhabditis elegans animal model].

    Science.gov (United States)

    Aksoy, Deniz; Şen, Ece

    2015-10-01

    Salmonellosis, caused by non-typhoidal Salmonella enterica serovars with the consumption of contaminated food, is one of the leading food-borne disease that makes microbial food safety an important public health issue. This study was performed in order to determine the antibiotic resistance, serotyping, plasmid profiles and pathogenicity potentials of food-borne Salmonella isolates in Caenorhabditis elegans animal model system in Edirne province, located at Thrace region of Turkey. In this study, 32 Salmonella isolates, of which 26 belonged to Infantis, four to Enteritidis, one to Telaviv and one to Kentucky serovars, isolated from chicken carcasses were used. Antibiotic resistance profiles were determined by disc diffusion and broth microdilution methods. A new C.elegans nematode animal model system was used to determine the pathogenicity potential of the isolates. The antibiotic resistance profiles revealed that one (3.1%) isolate was resistant to gentamicin, two (6.2%) to ciprofloxacin, three (9.4%) to ampicillin, 18 (56.3%) to kanamycin, 19 (60.8%) to neomycin, 25 (78.1%) to tetracycline, 25 (78.1%) to trimethoprim, 26 (81.25%) to nalidixic acid, 27 (84.4%) to streptomycin and 32 (100%) to sulfonamide. All of the 32 strains were susceptible to chloramphenicol and ampicillin/sulbactam. High levels of resistance to streptomycin, nalidixic acid, tetracycline, trimethoprim, sulfonamide, kanamycin and neomycin was determined. According to the plasmid analysis, six isolates (18.75%) harboured 1-3 plasmids with sizes between 1.2 and 42.4 kb. In C.elegans nematode animal model system, the time (in days) required to kill 50% (TD50) of nematodes was calculated for each experimental group. TD50 values of the nematode group fed with S.Typhimurium ATCC 14028 that was used as the positive control and another group fed with E.coli OP50 as the negative control were 4.2 ± 0.5 days and 8.0 ± 0.02 days, respectively. TD50 of the groups fed with Salmonella isolates ranged

  8. 200 Areas Remedial Investigation/Feasibility Study Implementation Plan - Environmental Restoration Program

    International Nuclear Information System (INIS)

    The 200 Areas Remedial Investigation/Feasibility Study Implementation Plan - Environmental Restoration Program (Implementation Plan) addresses approximately 700 soil waste sites (and associated structures such as pipelines) resulting from the discharge of liquids and solids from processing facilities to the ground (e.g., ponds, ditches, cribs,burial grounds) in the 200 Areas and assigned to the Environmental Restoration Program. The Implementation Plan outlines the framework for implementing assessment activities in the 200 Areas to ensure consistency in documentation, level of characterization, and decision making. The Implementation Plan also consolidates background information and other typical work plan materials, to serve as a single referenceable source for this type of information

  9. Investigation to determine staff exposure and describe animal bite surveillance after detection of a rabid zebra in a safari lodge in Kenya, 2011

    OpenAIRE

    Obonyo, Mark; Arvelo, Wences; Kadivane, Samuel; Orundu, Moses; Lankau, Emily; Gakuya, Francis; Munyua, Peninah; Githinji, Jane; Marano, Nina; Njenga, Kariuki; Omolo, Jared; Montgomery, Joel

    2014-01-01

    Introduction Rabies is a fatal viral infection, resulting in >55,000 deaths globally each year. In August 2011, a young orphaned zebra at a Kenyan safari lodge acquired rabies and potentially exposed >150 tourists and local staff. An investigation was initiated to determine exposures among the local staff, and to describe animal bite surveillance in the affected district. Methods We interviewed lodge staff on circumstances surrounding the zebra's illness and assessed their exposure status. We...

  10. Animal brucellosis in Egypt.

    Science.gov (United States)

    Wareth, Gamal; Hikal, Ahmed; Refai, Mohamed; Melzer, Falk; Roesler, Uwe; Neubauer, Heinrich

    2014-11-13

    Brucellosis is a highly contagious zoonosis that affects the public health and economic performance of endemic as well as non-endemic countries. In developing nations, brucellosis is often a very common but neglected disease. The purpose of this review is to provide insight about brucellosis in animal populations in Egypt and help to understand the situation from 1986 to 2013. A total of 67 national and international scientific publications on serological investigations, isolation, and biotyping studies from 1986 to 2013 were reviewed to verify the current status of brucellosis in animal populations in Egypt. Serological investigations within the national surveillance program give indirect proof for the presence of brucellosis in cattle, buffaloes, sheep, goats, and camels in Egypt. Serologic testing for brucellosis is a well-established procedure in Egypt, but most of the corresponding studies do not follow the scientific standards. B. melitensis biovar (bv) 3, B. abortus bv 1, and B. suis bv 1 have been isolated from farm animals and Nile catfish. Brucellosis is prevalent nationwide in many farm animal species. There is an obvious discrepancy between official seroprevalence data and data from scientific publications. The need for a nationwide survey to genotype circulating Brucellae is obvious. The epidemiologic situation of brucellosis in Egypt is unresolved and needs clarification.

  11. "That's My Kind of Animal!" Designing and Assessing an Outdoor Science Education Program with Children's Megafaunaphilia in Mind

    OpenAIRE

    Migliarese, Nicole Lynne

    2011-01-01

    Children are naturally curious about plants and animals, and while they no longer have the same amount of direct experience with and knowledge of the natural world that previous generations did, they do have a high degree of exposure to mediated nature through television, film, and the Internet. The media, however, are often criticized for the highly stylized ways they represent the natural world. In the absence of direct, hands-on nature experiences with their own local plants and animals, c...

  12. Quantitation of dopamine transporter blockade by methylphenidate: first in vivo investigation using [{sup 123}I]FP-CIT and a dedicated small animal SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Nikolaus, Susanne; Wirrwar, Andreas; Antke, Christina; Arkian, Shahram; Mueller, Hans-Wilhelm; Larisch, Rolf [Heinrich-Heine University, Clinic of Nuclear Medicine, Duesseldorf (Germany); Schramm, Nils [Research Center Juelich, Central Laboratory for Electronics, Juelich (Germany)

    2005-03-01

    The aim of this study was to investigate the feasibility of assessing dopamine transporter binding after treatment with methylphenidate in the rat using a recently developed high-resolution small animal single-photon emission computed tomograph (TierSPECT) and [{sup 123}I]FP-CIT. [{sup 123}I]FP-CIT was administered intravenously 1 h after intraperitoneal injection of methylphenidate (10 mg/kg) or vehicle. Animals underwent scanning 2 h after radioligand administration. The striatum was identified by superimposition of [{sup 123}I]FP-CIT scans with bone metabolism and perfusion scans obtained with {sup 99m}Tc-DPD and {sup 99m}Tc-tetrofosmin, respectively. As these tracers do not pass the blood-brain barrier, their distribution permits the identification of extracerebral anatomical landmarks such as the orbitae and the harderian glands. The cerebellum was identified by superimposing [{sup 123}I]FP-CIT scans with images of brain perfusion obtained with {sup 99m}Tc-HMPAO. Methylphenidate-treated animals and vehicle-treated animals yielded striatal equilibrium ratios (V''{sub 3}) of 0.24{+-}0.26 (mean {+-} SD) and 1.09{+-}0.42, respectively (ttest, two-tailed, p<0.0001). Cortical V''{sub 3} values amounted to 0.05{+-}0.28 (methylphenidate) and 0.3{+-}0.39 (saline, p=0.176). This first in vivo study of rat dopamine transporter binding after pre-treatment with methylphenidate showed a mean reduction of 78% in striatal [{sup 123}I]FP-CIT accumulation. The results can be interpreted in terms of a pharmacological blockade in the rat striatum and show that in vivo quantitation of dopamine transporter binding is feasible with [{sup 123}I]FP-CIT and the TierSPECT. This may be of future relevance for in vivo investigations on rat models of attention deficit/hyperactivity disorder. Furthermore, our findings suggest that investigations in other animal models, e.g. of Parkinson's and Huntington's disease, may be feasible using SPECT radioligands and

  13. Hybrid MPI+OpenMP Programming of an Overset CFD Solver and Performance Investigations

    Science.gov (United States)

    Djomehri, M. Jahed; Jin, Haoqiang H.; Biegel, Bryan (Technical Monitor)

    2002-01-01

    This report describes a two level parallelization of a Computational Fluid Dynamic (CFD) solver with multi-zone overset structured grids. The approach is based on a hybrid MPI+OpenMP programming model suitable for shared memory and clusters of shared memory machines. The performance investigations of the hybrid application on an SGI Origin2000 (O2K) machine is reported using medium and large scale test problems.

  14. Labelling study of galacturonic acid with Tc-99m and investigation of the biokinetic behaviour in experimental animals

    International Nuclear Information System (INIS)

    The main criterion in the selection of a proper ligand to be labelled with Technetium is to match the requirement of a radiopharmaceutical of good biological specificity, where the target organ-to-background ratio is considerably high. Perliminary study on experimental animals has shown, that galacturonic acid is among those ligands of high renal specificity after complexing with Tc-99. In this communication we describe for the first time the labelling of galacturonic acid with Tc-99, using stannous chloride as a reducing agent for pertechnetate. The radioanalytical results assessed by gelchromatography column scanning (GCS) method, reveal that, the labelling efficiency of (Tc)99-galacturonate complex is promoted by raising the pH of the reaction mixture to a value higher than 7 using tris (hydroxymethyl) aminomethane buffer. The optimal amounts of the reactants to obtain a high labelled and stable complex with high kidney uptake, were found to be not less than 50 mg galacturonic acid and not more than 200 Mg SnCl2.H2O in the preparation

  15. Animal Assisted Therapy (AAT) Program As a Useful Adjunct to Conventional Psychosocial Rehabilitation for Patients with Schizophrenia: Results of a Small-scale Randomized Controlled Trial

    Science.gov (United States)

    Calvo, Paula; Fortuny, Joan R.; Guzmán, Sergio; Macías, Cristina; Bowen, Jonathan; García, María L.; Orejas, Olivia; Molins, Ferran; Tvarijonaviciute, Asta; Cerón, José J.; Bulbena, Antoni; Fatjó, Jaume

    2016-01-01

    Currently, one of the main objectives of human–animal interaction research is to demonstrate the benefits of animal assisted therapy (AAT) for specific profiles of patients or participants. The aim of this study is to assess the effect of an AAT program as an adjunct to a conventional 6–month psychosocial rehabilitation program for people with schizophrenia. Our hypothesis is that the inclusion of AAT into psychosocial rehabilitation would contribute positively to the impact of the overall program on symptomology and quality of life, and that AAT would be a positive experience for patients. To test these hypotheses, we compared pre–program with post–program scores for the Positive and Negative Syndrome Scale (PANSS) and the EuroQoL-5 dimensions questionnaire (EuroQol-5D), pre–session with post–session salivary cortisol and alpha–amylase for the last four AAT sessions, and adherence rates between different elements of the program. We conducted a randomized, controlled study in a psychiatric care center in Spain. Twenty–two institutionalized patients with chronic schizophrenia completed the 6–month rehabilitation program, which included individual psychotherapy, group therapy, a functional program (intended to improve daily functioning), a community program (intended to facilitate community reintegration) and a family program. Each member of the control group (n = 8) participated in one activity from a range of therapeutic activities that were part of the functional program. In place of this functional program activity, the AAT–treatment group (n = 14) participated in twice–weekly 1–h sessions of AAT. All participants received the same weekly total number of hours of rehabilitation. At the end of the program, both groups (control and AAT–treatment) showed significant improvements in positive and overall symptomatology, as measured with PANSS, but only the AAT–treatment group showed a significant improvement in negative symptomatology

  16. Animal Assisted Therapy (AAT) Program As a Useful Adjunct to Conventional Psychosocial Rehabilitation for Patients with Schizophrenia: Results of a Small-scale Randomized Controlled Trial.

    Science.gov (United States)

    Calvo, Paula; Fortuny, Joan R; Guzmán, Sergio; Macías, Cristina; Bowen, Jonathan; García, María L; Orejas, Olivia; Molins, Ferran; Tvarijonaviciute, Asta; Cerón, José J; Bulbena, Antoni; Fatjó, Jaume

    2016-01-01

    Currently, one of the main objectives of human-animal interaction research is to demonstrate the benefits of animal assisted therapy (AAT) for specific profiles of patients or participants. The aim of this study is to assess the effect of an AAT program as an adjunct to a conventional 6-month psychosocial rehabilitation program for people with schizophrenia. Our hypothesis is that the inclusion of AAT into psychosocial rehabilitation would contribute positively to the impact of the overall program on symptomology and quality of life, and that AAT would be a positive experience for patients. To test these hypotheses, we compared pre-program with post-program scores for the Positive and Negative Syndrome Scale (PANSS) and the EuroQoL-5 dimensions questionnaire (EuroQol-5D), pre-session with post-session salivary cortisol and alpha-amylase for the last four AAT sessions, and adherence rates between different elements of the program. We conducted a randomized, controlled study in a psychiatric care center in Spain. Twenty-two institutionalized patients with chronic schizophrenia completed the 6-month rehabilitation program, which included individual psychotherapy, group therapy, a functional program (intended to improve daily functioning), a community program (intended to facilitate community reintegration) and a family program. Each member of the control group (n = 8) participated in one activity from a range of therapeutic activities that were part of the functional program. In place of this functional program activity, the AAT-treatment group (n = 14) participated in twice-weekly 1-h sessions of AAT. All participants received the same weekly total number of hours of rehabilitation. At the end of the program, both groups (control and AAT-treatment) showed significant improvements in positive and overall symptomatology, as measured with PANSS, but only the AAT-treatment group showed a significant improvement in negative symptomatology. Adherence to the AAT

  17. Animal assisted therapy (AAT program as a useful adjunct to conventional psychosocial rehabilitation for patients with schizophrenia: results of a small-scale randomized controlled trial.

    Directory of Open Access Journals (Sweden)

    Paula Calvo

    2016-05-01

    Full Text Available Currently, one of the main objectives of human-animal interaction research is to demonstrate the benefits of animal-assisted therapy (AAT for specific profiles of patients or participants.The aim of this study is to assess the effect of an AAT program as an adjunct to a conventional 6-month psychosocial rehabilitation program for people with schizophrenia. Our hypothesis is that the inclusion of AAT into psychosocial rehabilitation would contribute positively to the impact of the overall program on symptomology and quality of life, and that AAT would be a positive experience for patients. To test these hypotheses, we compared pre-program with post-program scores for the Positive and Negative Syndrome Scale (PANSS and the EuroQoL-5 dimensions questionnaire (EuroQol-5D, pre-session with post-session salivary cortisol and alpha-amylase for the last four AAT sessions, and adherence rates between different elements of the program.We conducted a randomized, controlled study in a psychiatric care center in Spain. Twenty-two institutionalized patients with chronic schizophrenia completed the 6-month rehabilitation program, which included individual psychotherapy, group therapy, a functional program (intended to improve daily functioning, a community program (intended to facilitate community reintegration and a family program. Each member of the control group (n=8 participated in one activity from a range of therapeutic activities that were part of the functional program. In place of this functional program activity, the AAT-treatment group (n=14 participated in twice-weekly 1-hour sessions of AAT. All participants received the same weekly total number of hours of rehabilitation. At the end of the program, both groups (control and AAT-treatment showed significant improvements in positive and overall symptomatology, as measured with PANSS, but only the AAT-treatment group showed a significant improvement in negative symptomatology. Adherence to the AAT

  18. Animal Assisted Therapy (AAT) Program As a Useful Adjunct to Conventional Psychosocial Rehabilitation for Patients with Schizophrenia: Results of a Small-scale Randomized Controlled Trial.

    Science.gov (United States)

    Calvo, Paula; Fortuny, Joan R; Guzmán, Sergio; Macías, Cristina; Bowen, Jonathan; García, María L; Orejas, Olivia; Molins, Ferran; Tvarijonaviciute, Asta; Cerón, José J; Bulbena, Antoni; Fatjó, Jaume

    2016-01-01

    Currently, one of the main objectives of human-animal interaction research is to demonstrate the benefits of animal assisted therapy (AAT) for specific profiles of patients or participants. The aim of this study is to assess the effect of an AAT program as an adjunct to a conventional 6-month psychosocial rehabilitation program for people with schizophrenia. Our hypothesis is that the inclusion of AAT into psychosocial rehabilitation would contribute positively to the impact of the overall program on symptomology and quality of life, and that AAT would be a positive experience for patients. To test these hypotheses, we compared pre-program with post-program scores for the Positive and Negative Syndrome Scale (PANSS) and the EuroQoL-5 dimensions questionnaire (EuroQol-5D), pre-session with post-session salivary cortisol and alpha-amylase for the last four AAT sessions, and adherence rates between different elements of the program. We conducted a randomized, controlled study in a psychiatric care center in Spain. Twenty-two institutionalized patients with chronic schizophrenia completed the 6-month rehabilitation program, which included individual psychotherapy, group therapy, a functional program (intended to improve daily functioning), a community program (intended to facilitate community reintegration) and a family program. Each member of the control group (n = 8) participated in one activity from a range of therapeutic activities that were part of the functional program. In place of this functional program activity, the AAT-treatment group (n = 14) participated in twice-weekly 1-h sessions of AAT. All participants received the same weekly total number of hours of rehabilitation. At the end of the program, both groups (control and AAT-treatment) showed significant improvements in positive and overall symptomatology, as measured with PANSS, but only the AAT-treatment group showed a significant improvement in negative symptomatology. Adherence to the AAT

  19. Serological Investigation Test of Brucellosis in Domestic Animal%家畜布鲁氏菌病的血清学调查

    Institute of Scientific and Technical Information of China (English)

    多里坤·努尔沙发; 闫晶华; 米吉提; 地力夏提

    2012-01-01

    In this article, to obtain current condition in management effectiveness and prognosis of brucellosis in domestic animal in our region and heighten the ability of different level administrations in earlywarning and management effectiveness of brucellosis ,carry on serological investigation test of brucellosis in domestic animal in several counties and providing some advise in brucellosis epidemic protection situation.%本文通过对新疆部分县家畜布鲁氏茵病的血清学调查,实际掌握新疆家畜布鲁氏菌病防控工作的真实效果,预测家畜布病疫情的流行态势,提高各级有关部门对动物布病的预警能力和防控效果,并且提出了一些对布病防控工作的建议。

  20. [Strategic considerations on the design and choice of animal models for non-clinical investigations of cell-based medicinal products].

    Science.gov (United States)

    Lehmann, Jörg; Schulz, Ronny M; Sanzenbacher, Ralf

    2015-11-01

    For the development of medicinal products animal models are still indispensable to demonstrate efficacy and safety prior to first use in humans. Advanced therapy medicinal products (ATMP), which include cell-based medicinal products (CBMP), differ in their pharmacology and toxicology compared to conventional pharmaceuticals, and thus, require an adapted regime for non-clinical development. Developers are, therefore, challenged to develop particular individual concepts and to reconcile these with regulatory agencies. Guidelines issued by the European Medicines Agency (EMA), the U.S. Food and Drug Administration (FDA) and other sources can provide direction.The published approaches for non-clinical testing of efficacy document that homologous animal models where the therapeutic effect is investigated in a disease-relevant animal model utilizing cells derived from the same species are commonly used. The challenge is that the selected model should reflect the human disease in all critical features and that the cells should be comparable to the investigated human medicinal product in terms of quality and biological activity. This is not achievable in all cases. In these cases, alternative methods may provide supplemental information. To demonstrate the scientific proof-of-concept (PoC), small animal models such as mice or rats are preferred. During the subsequent product development phase, large animal models (i.e. sheep, minipigs, dogs) must be considered, as they may better reflect the anatomical or physiological situation in humans. In addition to efficacy, those models may also be suitable to prove some safety aspects of ATMP (e.g. regarding dose finding, local tolerance, or undesired interactions and effects of the administered cells in the target tissue). In contrast, for evaluation of the two prominent endpoints for characterizing the safety of ATMP (i.e. biodistribution, tumorigenicity) heterologous small animal models, especially immunodeficient mouse strains

  1. [Strategic considerations on the design and choice of animal models for non-clinical investigations of cell-based medicinal products].

    Science.gov (United States)

    Lehmann, Jörg; Schulz, Ronny M; Sanzenbacher, Ralf

    2015-11-01

    For the development of medicinal products animal models are still indispensable to demonstrate efficacy and safety prior to first use in humans. Advanced therapy medicinal products (ATMP), which include cell-based medicinal products (CBMP), differ in their pharmacology and toxicology compared to conventional pharmaceuticals, and thus, require an adapted regime for non-clinical development. Developers are, therefore, challenged to develop particular individual concepts and to reconcile these with regulatory agencies. Guidelines issued by the European Medicines Agency (EMA), the U.S. Food and Drug Administration (FDA) and other sources can provide direction.The published approaches for non-clinical testing of efficacy document that homologous animal models where the therapeutic effect is investigated in a disease-relevant animal model utilizing cells derived from the same species are commonly used. The challenge is that the selected model should reflect the human disease in all critical features and that the cells should be comparable to the investigated human medicinal product in terms of quality and biological activity. This is not achievable in all cases. In these cases, alternative methods may provide supplemental information. To demonstrate the scientific proof-of-concept (PoC), small animal models such as mice or rats are preferred. During the subsequent product development phase, large animal models (i.e. sheep, minipigs, dogs) must be considered, as they may better reflect the anatomical or physiological situation in humans. In addition to efficacy, those models may also be suitable to prove some safety aspects of ATMP (e.g. regarding dose finding, local tolerance, or undesired interactions and effects of the administered cells in the target tissue). In contrast, for evaluation of the two prominent endpoints for characterizing the safety of ATMP (i.e. biodistribution, tumorigenicity) heterologous small animal models, especially immunodeficient mouse strains

  2. A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation.

    Directory of Open Access Journals (Sweden)

    Andreas Schaefer

    Full Text Available Previous small animal models for simulation of mechanical unloading are solely performed in healthy or infarcted hearts, not representing the pathophysiology of hypertrophic and dilated hearts emerging in heart failure patients. In this article, we present a new and economic small animal model to investigate mechanical unloading in hypertrophic and failing hearts: the combination of transverse aortic constriction (TAC and heterotopic heart transplantation (hHTx in rats.To induce cardiac hypertrophy and failure in rat hearts, three-week old rats underwent TAC procedure. Three and six weeks after TAC, hHTx with hypertrophic and failing hearts in Lewis rats was performed to induce mechanical unloading. After 14 days of mechanical unloading animals were euthanatized and grafts were explanted for further investigations.50 TAC procedures were performed with a survival of 92% (46/50. When compared to healthy rats left ventricular surface decreased to 5.8±1.0 mm² (vs. 9.6± 2.4 mm² (p = 0.001 after three weeks with a fractional shortening (FS of 23.7± 4.3% vs. 28.2± 1.5% (p = 0.01. Six weeks later, systolic function decreased to 17.1± 3.2% vs. 28.2± 1.5% (p = 0.0001 and left ventricular inner surface increased to 19.9±1.1 mm² (p = 0.0001. Intraoperative graft survival during hHTx was 80% with 46 performed procedures (37/46. All transplanted organs survived two weeks of mechanical unloading.Combination of TAC and hHTx in rats offers an economic and reproducible small animal model enabling serial examination of mechanical unloading in a truly hypertrophic and failing heart, representing the typical pressure overloaded and dilated LV, occurring in patients with moderate to severe heart failure.

  3. INVESTIGATION ON EFFECT OF DRUG DOSING REGIMENTS ON DRUG DELIVERY IN SOLID TUMOR VIA LUMPED PARAMETER MODELING AND ANIMAL EXPERIMENTS

    Institute of Scientific and Technical Information of China (English)

    GAO Ci-xiu; XU Shi-xiong; JIANG Yu-ping; TU Jiang-long

    2009-01-01

    This work aims to investigate the effects of dosing regiments on drug delivery in solid tumors and to validate them with experiments on rats.The lumped parameter models of pharmacokinetics and of drug delivery in tumor were developed to simulate time courses of average drug concentration(Ct)of tumor interstitium in two types of dosing regiments(i.e.,single-shot and triple-shot ones).The two regiments were performed via antitumor drug,hydroxycamptothecin(HCPT),on rats,to measure the drug concentration in the tumor.The simulations of the drug concentration in the tumor of the two dosing regiments were conducted and compared with the experimental data on rats.The coefficients in the models were investigated.It is concluded that the triple-shot method is more effective than that of single-shot injection.The present lumped-parameter model is quantitatively competent for drug delivery in solid tumor.

  4. Comparison of methods and animal models commonly used for investigation of fecal microbiota: Effects of time, host and gender

    DEFF Research Database (Denmark)

    Bernbom, Nete; Nørrung, Birgit; Saadbye, Peter;

    2006-01-01

    Denaturing gradient gel electrophoresis (DGGE), terminal restriction fragment length polymorphism (T-RFLP) and plating on selective agars were used to study variation in the fecal microbiota of rats over time as well as variation between individuals. Investigated rats were either conventional...... and specific pathogen free (SPF). or human flora associated (HFA). A higher variation (p RFLP profiles of fecal microbiota from SPF and HFA rats revealed that variation over time was less significant than...

  5. " Animal, trop animal "

    OpenAIRE

    Potestà, Andréa

    2010-01-01

    Dans la tradition philosophique, on trouve plusieurs définitions de l’homme. La célèbre définition aristotélicienne, zoon logon echon (animal doué du langage ou animal rationnel) fournit le paradigme ainsi que la méthode de toutes les définitions successives. Il s’agit d’ajouter au vivant, à l’animal, quelque chose d’autre, quelque chose de plus, qui permette de le caractériser et le fasse entendre comme différent des bêtes. Cette diversité peut être conçue différemment : en tant qu’élévation...

  6. Immunohistological Evaluation of Revascularized Immature Permanent Necrotic Teeth Treated by Platelet-Rich Plasma: An Animal Investigation

    Directory of Open Access Journals (Sweden)

    Saeed Moradi

    2016-09-01

    Full Text Available Objective: Pulp regeneration within the root canal of necrotic teeth is considered an ideal treatment to allow for continued root development and recover teeth vitality. This study aims to evaluate the inductive effect of platelet-rich plasma (PRP on expression of angiogenesis factors and pulpal revascularization of immature necrotic teeth. Materials and Methods: In this experimental animal study, we randomly divided 28 immature premolars from two mixed breed dogs into four groups, two experimental, negative and a positive control. Premolars in negative control group were left intact to develop normally. In the positive control and experimental groups, we removed the pulps and induced pulp necrosis, after which the chambers were sealed. Then, we applied the revascularization protocol in the experimental teeth located in the right quadrant. Two months later, the same protocol was applied to the left quadrant. The root canals were disinfected by irrigation with sodium hypochlorite (NaOCl solution and application a triple antibiotic past. Following the induction of a blood clot (BC inside the canal space, the coronal portion of the canals was assigned to either of two experimental groups: group 1 [BC+PRP+ mineral trioxide aggregate (MTA], group 2 (BC+MTA. Access cavities were sealed with a Glass Ionomer. The jaws that held the teeth were processed for histologic analysis of newly formed tissue and immunohistochemical evaluation according to vascular endothelial growth factor (VEGF and factor VIII expressions in the canals. Results: Histological analysis demonstrated no significant difference in the formation of new vital tissue inside the root canals between groups1 (42.8% and 2 (43.5%, P>0.05. Based on immunohistochemical evaluation, micro-vessel density (MVD of the granulation tissues in both groups were similar and were higher compared with the normal pulp. We observed strongly positive expressions of VEGF and factor VIII in the stromal and

  7. Controls-structures interaction guest investigator program: Overview and phase 1 experimental results and future plans

    Science.gov (United States)

    Smith-Taylor, Rudeen; Tanner, Sharon E.

    1993-01-01

    The NASA Controls-Structures Interaction (CSI) Guest Investigator program is described in terms of its support of the development of CSI technologies. The program is based on the introduction of CSI researchers from industry and academia to available test facilities for experimental validation of technologies and methods. Phase 1 experimental results are reviewed with attention given to their use of the Mini-MAST test facility and the facility for the Advance Control Evaluation of Structures. Experiments were conducted regarding the following topics: collocated/noncollocated controllers, nonlinear math modeling, controller design, passive/active suspension systems design, and system identification and fault isolation. The results demonstrate that significantly enhanced performance from the control techniques can be achieved by integrating knowledge of the structural dynamics under consideration into the approaches.

  8. Evaluation of an implementation model: a national investigation of VA residential programs.

    Science.gov (United States)

    Cook, Joan M; Dinnen, Stephanie; Coyne, James C; Thompson, Richard; Simiola, Vanessa; Ruzek, Josef; Schnurr, Paula P

    2015-03-01

    This national investigation utilizes qualitative data to evaluate an implementation model regarding factors influencing provider use of two evidence-based treatments for posttraumatic stress disorder (PTSD). Semi-structured qualitative interviews with 198 mental health providers from 38 Department of Veterans Affairs' (VA) residential treatment programs were used to explore these issues regarding prolonged exposure (PE) and cognitive processing therapy (CPT) in VA residential PTSD programs. Several unique and some overlapping predictors emerged. Leadership was viewed as an influence on implementation for both CPT and PE, while a lack of dedicated time and resources was viewed as a deterrent for both. Compatibility of CPT with providers' existing practices and beliefs, the ability to observe noticeable patient improvement, a perceived relative advantage of CPT over alternative treatments, and the presence of a supportive peer network emerged as influential on CPT implementation. Leadership was associated with PE implementation. Implications for the design and improvement of training and implementation efforts are discussed. PMID:24817625

  9. An Exploratory Study of Apache Middle School Students' Computer Animation.

    Science.gov (United States)

    Stokrocki, Mary; Buckpitt, Marcia

    The paper describes a participant observation study of a 3 week summer art program for Apache middle school students on the White Mountain Reservation. Computer art skills, specifically animation using a menu-driven computer paint program, were the focus of the investigation. Because it was in the context of a summer program, instruction was…

  10. A short historical investigation into cross-cultural Australian ideas about the marine animal group Teredinidae, their socioecological consequences and some options

    Directory of Open Access Journals (Sweden)

    Mary Gardner

    2013-10-01

    Full Text Available How are contemporary multicultural coastal Australians, Aboriginals and settlers alike, to develop wiser ideas and practices towards marine animals as well as each other? To illustrate the importance and complexity of this question, I offer a short historical investigation of some contrasting ideas and practices held by Australian Aboriginal and settler cultures about marine animals of the group Teredinidae. I present two “screenshots”: one from the period 1798-1826 and another from 1970-2012. The first period examines a negative but influential interpretation by Thomas Malthus of a cross cultural encounter featuring Australian Aboriginal consumption of local Teredinidae known as “cobra”. While this cultural tone remains largely unchanged in the second period, the biological understanding of the marine animals has developed greatly. So has awareness of the socioecology of Teredinidae: their estuarine habitats and cultural significance. Their potential role as subjects of community based monitoring is undeveloped but could serve overlapping concerns of environmental justice as well as the restoration and “future proofing” of habitats. Such a new composite of ideas and practices will rely on better integration of biology with community based social innovations. A symbolic beginning would be a change in Australian English colloquialisms for Teredinidae, from the erroneous “shipworm” or “mangrove worm” to the more accurate “burrowing clam”.

  11. Investigation program on PWR-steel-containment behavior under accident conditions

    International Nuclear Information System (INIS)

    This report is a first documentation of the KfK/PNS activities and plans to investigate the behaviour of steel containments under accident conditions. The investigations will deal with a free standing spherical containment shell built for the latest type of a German pressurized water reactor. The diameter of the containment shell is 56 m. The minimum wall thickness is 38 mm. The material used is the ferritic steel 15MnNi63. According to the actual planning the program is concerned with four different problems which are beyond the common design and licensing practice: Containment behavior under quasi-static pressure increase up to containment failure. Containment behavior under high transient pressures. Containment oscillations due to earthquake loadings; consideration of shell imperfections. Containment buckling due to earthquake loadings. The investigation program consists of both theoretical and experimental activities including membrane tests allowing for very high plastic strains and oscillation tests with a thin-walled, high-accurate spherical shell. (orig.)

  12. Investigating the Efficacy of an Intensive English Program and the L2 Learners’ Learning Styles

    Directory of Open Access Journals (Sweden)

    Rebecca Lee Su Ping

    2014-12-01

    Full Text Available Past research has found that many pre-university L2 learners, having completed an Intensive English Program (IEP still have difficulty in undertaking various disciplines in English-speaking tertiary institutions and continue to exhibit numerous linguistic problems (Bialystok, 2001, Celce Murcia 2001. The purpose of this paper is to present the findings on the investigation of L2 learners’ English proficiency in reading, writing, grammar, listening and speaking upon their completion of an Intensive English (IE program using their IELTS (Academic, in-house exams and English Placement Tests (EPT scores, and the efficacy of IE program.  IELTS test is chosen for this study due to its increasing popularity in Malaysia and its internationally recognised value and quality.  The study was conducted in two parts. In Part One, all 72 Level 4 IE students were given an in-house EPT (English Placement Test pre-test on their entry and another EPT post-test on their exit, and then their pre-test and post-test results were compared.  In Part Two, 22 volunteers sat the IELTS test at the end of the program. The IELTS results of the 22 volunteers were compared with those who did not.  Data were analyzed using both quantitative and qualitative methods. This paper hopes to shed some light on (i whether or not L2 learners’ English language proficiency can be significantly enhanced and influenced by an intensive English program and (ii how leaners’ perception of their own learning strategies influence their learning progress. 

  13. Animal production and health newsletter. No. 24

    International Nuclear Information System (INIS)

    The Newsletter announces meetings and training programs in animal husbandry and animal health related activities undertaken by the IAEA. Short communications on coordinated research programs in animal production and health are included

  14. Group Investigation in a College English Program at a Chinese University:A Case Study

    Institute of Scientific and Technical Information of China (English)

    LIU Hao; CAI Ning; QIU Hu; PAN Yi; LIU Zi

    2015-01-01

    This study investigated the application and the effect of Group Investigation (GI) in the College English Program in a Chinese University. A qualitative case study method was used to understand the GI system used by Chinese instructors as well as the achievements acquired and challenges met by the participants. Three instructors and fifteen second-year-undergraduates tak⁃ing a course titled Sources of European Culture participated. Interviews, observations, and documents were used to collect the da⁃ta. Data analysis showed Chinese instructors applied a GI technique similar to that discussed by Johnson and Johnson ( 1999);how⁃ever, GI in the Chinese context demanded more effort from the teacher for designing tasks and provided help in modeling uses of English and in preparing visual, especially PowerPoint, presentations. Although participants used their mother tongue at some stages, their autonomy over English learning was activated, and horizons in the course content were broadened.

  15. A study to investigate the effectiveness of successful intelligence training program to increase academic hope

    Directory of Open Access Journals (Sweden)

    Mahbobeh Samavatian

    2014-02-01

    Full Text Available The purpose of this study is to investigate the effectiveness of successful intelligence training program on academic hopefulness of probation students of Esfahan University of Technology. The research is semi-experimental of pre-test, post-test type with control group. Research population includes all probation students of Esfahan University of Technology. The study chooses 30 female and male students and assigns them randomly into two groups of experimental and control. Experimental group participate in 13 successful intelligence-training sessions for 13 weeks. Research tools consists of, Hope in certain aspects. Statistical analysis is conducted using SPSS18 on inferential statistics level proportionate to data analysis level. Statistical test hypothesis are analyzed through univariate covariance and multivariate covariance analysis. The results show that successful intelligence program training was effective to enhance hopefulness of probation students (p < 0.05. Given the results of present research, successful intelligence program training can be used as an intervention method in order to decrease harms because of dormitory and student life.

  16. Geological Investigation Program for the Site of a New Nuclear Power Plant in Hungary

    Science.gov (United States)

    Gerstenkorn, András; Trosits, Dalma; Chikán, Géza; János Katona, Tamás

    2015-04-01

    Comprehensive site evalaution program is implemented for the new Nuclear Power Plant to be constructed at Paks site in Hungary with the aim of confirmation of acceptability of the site and definition of site-related design basis data. Most extensive part of this program is to investigate geological-tectonical features of the site with particular aim on the assessment of the capability of faults at and around the site, characterization of site seismic hazard, and definition of the design basis earthquake. A brief description of the scope and methodology of the geological, seismological, geophysical, geotechnical and hydrogeological investigations will be given on the poster. Main focus of the presentation is to show the graded structure and extent of the geological investigations that follow the needs and scale of the geological modeling, starting with the site and its vicinity, as well as on the near regional and the regional scale. Geological inverstigations includes several boreholes up-to the base-rock, plenty of boreholes discovering the Pannonian and large number of shallow boreholes for investigation of more recent development. The planning of the geological investigations is based on the 3D seismic survey performed around the site, that is complemented by shallow-seimic survey at and in the vicinity of the site. The 3D geophysical imaging provides essential geodynamic information to assess the capability of near site faults and for the seismic hazard analysis, as well as for the hydrogeological modeling. The planned seismic survey gives a unique dataset for understanding the spatial relationship between individual fault segments. Planning of the research (trenching, etc.) for paleoseismic manifestations is also based on the 3D seismic survey. The seismic survey and other geophysical data (including data of space geodesy) allow the amendment of the understanding and the model of the tectonic evolution of the area and geological events. As it is known from

  17. Biotecnologia animal

    Directory of Open Access Journals (Sweden)

    Luiz Lehmann Coutinho

    2010-01-01

    identification of the genomic region that contains the genes, but the confidence interval of the regions is usually large and may contain several genes. Candidate gene approach is limited to our restricted knowledge of the biological function of the genes. Sequencing of genomes and expressed sequences tags can provide identifying gene position and metabolic pathways associated with phenotypic trait. Integrating these strategies using bioinformatics software will allow identifying of novel genes for animal production. Then, animal breeding programs will include the information from DNA directly on evaluation of genetic value of livestock production.

  18. The Role of Ethnographic Interviewing in Climate Change Evaluation Research: Investigating Intended and Unintended program effects

    Science.gov (United States)

    Lloro-Bidart, T.

    2012-12-01

    Ethnographic interviewing is an under-utilized tool in climate change evaluation research, even though it has the potential to serve as a powerful method of data collection. The utility of the ethnographic interview lies in its ability to elicit responses from program participants describing what a program is in practice, shedding light on both intended and unintended program impacts. Drawing on evaluation work involving a federally-funded climate change grant at the University of California, Riverside, I will discuss how to design an ethnographic interview protocol in an effort to share "best practices" with other climate change evaluators. Particular attention will be given to applying ethnographic approaches to various program types, even those differing from the one discussed. I will share some of the concrete findings from my work on this grant, to serve as examples of the kinds of data evaluators can collect when employing an ethnographic approach to interviewing. UC Riverside's climate change grant is multi-faceted, however the component studied ethnographically was a science fair mentoring program. About twenty K-12 students from high poverty, ethnically diverse schools who expressed an interest in participating in science fair were paired up with graduate student mentors to simultaneously research climate change and design authentic science fair projects to compete at various levels. Since one of the stated goals of the grant is to "stimulate…students to consider climate science as a career track through experiential education activities" I was particularly interested in how student experiences with the project might differ from school science which has historically "pushed out" ethnically diverse students like those in many of Riverside's schools. (In the program students are able to interact one-on-one with a mentor and in school settings there is typically one teacher for more than thirty students). I also sought to understand student perceptions of

  19. River and river-related drainage area parameters for site investigation program

    International Nuclear Information System (INIS)

    In this paper, a number of parameters of importance to a determination of the function of running waters as transport channels for material from the continents to the sea are presented. We have assumed that retention mechanisms of material in the river and in the riparian zone will be covered by special investigations but tried to create a platform for such investigations by quantification of the extension of different main habitats. The choice of parameters has been made so that also the nature conservation value of the river can be preliminary established, and includes a general description of the river type and the inherent ecosystem. The material links directly to that presented in a previous report concerning site investigation programmes for lakes. The parameters have been divided into five groups: 1) The location of the object relative important gradients in the surrounding nature; 2) The river catchment area and its major constituents; 3) The river morphometry; 4) The river ecosystem; 5) Human-induced damages to the river ecosystem. The first two groups, principally based on the climate, hydrology, geology and vegetation of the catchment area, represent parameters that can be used to establish the rarity and representativity of the system, and will in the context of site investigation program be used as a basis for generalisation of the results. The third group, the river morphometry parameters, are standard parameters for the outline of sampling programmes and for calculations of the physical extension of key habitats in the system. The fourth group, the ecosystem of the river, includes physical, chemical and biological parameters required for determination of the influence from the terrestrial ecosystem of the catchment area, nutrient status, distribution of different habitats, and presence of fish in the system. In the context of site investigation program, the parameters in these two groups will be used for budget calculations of the flow of energy and

  20. Amazing Animals

    Science.gov (United States)

    Al-Kuwari, Najat Saad

    2007-01-01

    "Animals" is a three-part lesson plan for young learners with a zoo animal theme. The first lesson is full of activities to describe animals, with Simon Says, guessing games, and learning stations. The second lesson is about desert animals, but other types of animals could be chosen depending on student interest. This lesson teaches…

  1. Investigation to determine staff exposure and describe animal bite surveillance after detection of a rabid zebra in a safari lodge in Kenya, 2011

    Science.gov (United States)

    Obonyo, Mark; Arvelo, Wences; Kadivane, Samuel; Orundu, Moses; Lankau, Emily; Gakuya, Francis; Munyua, Peninah; Githinji, Jane; Marano, Nina; Njenga, Kariuki; Omolo, Jared; Montgomery, Joel

    2014-01-01

    Introduction Rabies is a fatal viral infection, resulting in >55,000 deaths globally each year. In August 2011, a young orphaned zebra at a Kenyan safari lodge acquired rabies and potentially exposed >150 tourists and local staff. An investigation was initiated to determine exposures among the local staff, and to describe animal bite surveillance in the affected district. Methods We interviewed lodge staff on circumstances surrounding the zebra's illness and assessed their exposure status. We reviewed animal bite report forms from the outpatient department at the district hospital. Results The zebra was reported bitten by a dog on 31st July 2011, became ill on 23rdAugust, and died three days later. There were 22 employees working at the lodge during that time. Six (27%) had high exposure due to contact with saliva (bottle feeding, veterinary care) and received four doses of rabies vaccine and one of immune-globulin, and 16 (73%) had low exposure due to casual contact and received only four doses of rabies vaccine. From January 2010 to September 2011, 118 cases of animal bites were reported in the district; 67 (57%) occurred among males, 65 (57%) in children <15 years old, and 61 (52%) were inflicted in a lower extremity. Domestic and stray dogs accounted for 98% of reported bites. Conclusion Dog bites remains the main source of rabies exposure in the district, but exposure can result from wildlife. This highlights the importance of a one health approach with strong communication between wildlife, veterinary, and human health sectors to improve rabies prevention and control. PMID:25815092

  2. Bio F1B hamster: a unique animal model with reduced lipoprotein lipase activity to investigate nutrient mediated regulation of lipoprotein metabolism

    Directory of Open Access Journals (Sweden)

    Cornish Marion L

    2007-12-01

    Full Text Available Abstract Background Bio F1B hamster is an inbred hybrid strain that is highly susceptible to diet-induced atherosclerosis. We previously reported that feeding a high fat fish oil diet to Bio F1B hamster caused severe hyperlipidaemia. In this study we compared the effects of various diets in the Bio F1B hamster and the Golden Syrian hamster, which is an outbred hamster strain to investigate whether genetic background plays an important role in dietary fat mediated regulation of lipoprotein metabolism. We further investigated the mechanisms behind diet-induced hyperlipidaemia in F1B hamster. Methods The Bio F1B and Golden Syrian hamsters, 8 weeks old, were fed high fat diets rich in either monounsaturated fatty acids, an n-6: n-3 ratio of 5 or a fish oil diet for 4 weeks. Animals were fasted overnight and blood and tissue samples were collected. Plasma was fractionated into various lipoprotein fractions and assayed for triacylglycerol and cholesterol concentrations. Plasma lipoprotein lipase activity was measured using radioisotope method. Microsomal triglyceride transfer protein activity was measured in the liver and intestine. Plasma apolipoproteinB48, -B100 and apolipoprotein E was measured using Western blots. Two-way ANOVA was used to determine the effect of diet type and animal strain. Results The fish oil fed F1B hamsters showed milky plasma after a 14-hour fast. Fish oil feeding caused accumulation of apolipoproteinB48 containing lipoprotein particles suggesting hindrance of triglyceride-rich lipoprotein clearance. There was no significant effect of diet or strain on hepatic or intestinal microsomal triglyceride transfer protein activity indicating that hyperlipidaemia is not due to an increase in the assembly or secretion of lipoprotein particles. F1B hamsters showed significantly reduced levels of lipoprotein lipase activity, which was inhibited by fish oil feeding. Conclusion Evidence is presented for the first time that alterations in

  3. 广州动漫产业发展调研与实证研究%Guangzhou animation industry development investigation and demonstrative research

    Institute of Scientific and Technical Information of China (English)

    赵佩华; 邹苇

    2012-01-01

    This artical mainly uses the mathods of statistical analysis,with observation and interview to make an in-depth investigation and study of the current development of the animation industry in Guangzhou,which based on the data from questionnaire survey.It provides not only decision-making empirical basis for Guangzhou animation industry,but also reference for related cultural and creative industries on the domestic other regions.%本文主要采用问卷调查的形式收集数据然后运用SPSS软件进行统计分析,并结合实地观察、重点访谈等方法,对广州动漫产业的发展现状作了深入的调查与分析,为广州市发展动漫产业提供决策的实证依据,同时对国内其它地区发展相关的文化创意产业提供参考和借鉴。

  4. Animal behavior and well-being symposium: Farm animal welfare assurance: science and application.

    Science.gov (United States)

    Rushen, J; Butterworth, A; Swanson, J C

    2011-04-01

    Public and consumer pressure for assurances that farm animals are raised humanely has led to a range of private and public animal welfare standards, and for methods to assess compliance with these standards. The standards usually claim to be science based, but even though researchers have developed measures of animal welfare and have tested the effects of housing and management variables on welfare within controlled laboratory settings, there are challenges in extending this research to develop on-site animal welfare standards. The standards need to be validated against a definition of welfare that has broad support and which is amenable to scientific investigation. Ensuring that such standards acknowledge scientific uncertainty is also challenging, and balanced input from all scientific disciplines dealing with animal welfare is needed. Agencies providing animal welfare audit services need to integrate these scientific standards and legal requirements into successful programs that effectively measure and objectively report compliance. On-farm assessment of animal welfare requires a combination of animal-based measures to assess the actual state of welfare and resource-based measures to identify risk factors. We illustrate this by referring to a method of assessing welfare in broiler flocks. Compliance with animal welfare standards requires buy-in from all stakeholders, and this will be best achieved by a process of inclusion in the development of pragmatic assessment methods and the development of audit programs verifying the conditions and continuous improvement of farm animal welfare. PMID:21216980

  5. Recent drilling program to investigate radionuclide migration at the Nevada Test Site

    International Nuclear Information System (INIS)

    Recent drilling affords new opportunities to investigate the occurrence, distribution and transport of radionuclides in the unsaturated and saturated zone at the Nevada Test Site (NTS), Nye County, Nevada. This program is unique becmise of the elevated activities of radionuclides encountered during drilling (> 3.7E+6 Bq/L 3H), extreme completion depths (> 950 m), the expense of constructing new wells (> $IE+6/borehole), and collaboration of government, academic, and industrial partners in the planning and execution of the program. The recent chilling is significant because it substantively augments earlier field of radionuclide migration at NTS, most notably the 1974 CAMBRIC RNM experiment Sites of five nuclear tests fired below or adjacent to the saturated zone have been drilled. Three of the events were fired in Yucca Flat which is a hydrologically closed basin and two were fired in fractured volcanics of Pahute Mesa. Results from Yucca Flat indicate that volatile and refractory radionuclides, fractionated at zero time, we not highly mobile under sawmted conditions. In contrast, borcholes completed on Pahute Mesa indicate Wgh concentrations of tritium (> 3.7E+6 Bq/L 3H) and other radionuclides may be rted more than 300 m from event cavities as dissolved species or as colloids

  6. Animal research

    DEFF Research Database (Denmark)

    Olsson, I.A.S.; Sandøe, Peter

    2012-01-01

    in research is analyzed from the viewpoint of three distinct ethical approaches: contractarianism, utilitarianism, and animal rights view. On a contractarian view, research on animals is only an ethical issue to the extent that other humans as parties to the social contract care about how research animals...... are faring. From the utilitarian perspective, the use of sentient animals in research that may harm them is an ethical issue, but harm done to animals can be balanced by benefit generated for humans and other animals. The animal rights view, when thoroughgoing, is abolitionist as regards the use of animals......This article presents the ethical issues in animal research using a combined approach of ethical theory and analysis of scientific findings with bearing on the ethical analysis. The article opens with a general discussion of the moral acceptability of animal use in research. The use of animals...

  7. Outstanding Junior Investigator Program: Progress report for the period ending December 31, 1988

    International Nuclear Information System (INIS)

    Since the submission of the last proposal for the Outstanding Junior Investigator Program in January 1988, research has entailed: an investigation of the nonperturbative geometry of string theory and loop space; a paper on the relation between nonlinear sigma models (with nonabelian topological interactions) and the Hubbard model, with application to high-temperature superconductivity; completion of the calculation of the Ricci curvature of DiffS1/SL(2,R); the determination that the low energy limit of closed string theory follows from the symplectic geometry of loop space; the demonstration that in a theory of gravity coupled to second rank antisymmetric tensor field there exist black holes with axionic charge. This charge can be measured by an interference experiment if a beam of strings (or particles if string theory is correct) passes through the black hole. The result is a generalization of the Bohm-Aharanov effect to second rank antisymmetric tensor fields. In this paper is a summary of this work together with last year's work. 46 refs

  8. Lake and lake-related drainage area parameters for site investigation program

    Energy Technology Data Exchange (ETDEWEB)

    Blomqvist, P.; Brunberg, A.K. [Uppsala Univ. (Sweden). Dept. of Limnology; Brydsten, L [Umeaa Univ. (Sweden). Dept. of Ecology and Environmental Science

    2000-09-01

    In this paper, a number of parameters of importance to a preliminary determination of the ecological function of lakes are presented. The choice of parameters have been made with respect to a model for the determination of the nature conservation values of lakes which is currently being developed by the authors of this report, but is also well suited for a general description of the lake type and the functioning of the inherent ecosystem. The parameters have been divided into five groups: (1) The location of the object relative important gradients in the surrounding nature; (2) The lake catchment area and its major constituents; (3) The lake morphometry; (4) The lake ecosystem; (5) Human-induced damages to the lake ecosystem. The first two groups, principally based on the climate, hydrology, geology and vegetation of the catchment area represent parameters that can be used to establish the rarity and representativity of the lake, and will in the context of site investigation program be used as a basis for generalisation of the results. The third group, the lake morphometry parameters, are standard parameters for the outline of sampling programmes and for calculations of the physical extension of different key habitats in the system. The fourth group, the ecosystem of the lake, includes physical, chemical and biological parameters required for determination of the stratification pattern, light climate, influence from the terrestrial ecosystem of the catchment area, trophic status, distribution of key habitats, and presence of fish and rare fauna and flora in the lake. In the context of site investigation program, the parameters in these two groups will be used for budget calculations of the flow of energy and material in the system. The fifth group, finally, describes the degree on anthropogenic influence on the ecosystem and will in the context of site investigation programmes be used to judge eventual malfunctioning within the entire, or parts of, the lake

  9. Lake and lake-related drainage area parameters for site investigation program

    International Nuclear Information System (INIS)

    In this paper, a number of parameters of importance to a preliminary determination of the ecological function of lakes are presented. The choice of parameters have been made with respect to a model for the determination of the nature conservation values of lakes which is currently being developed by the authors of this report, but is also well suited for a general description of the lake type and the functioning of the inherent ecosystem. The parameters have been divided into five groups: 1) The location of the object relative important gradients in the surrounding nature; 2) The lake catchment area and its major constituents; 3) The lake morphometry; 4) The lake ecosystem; 5) Human-induced damages to the lake ecosystem. The first two groups, principally based on the climate, hydrology, geology and vegetation of the catchment area represent parameters that can be used to establish the rarity and representativity of the lake, and will in the context of site investigation program be used as a basis for generalisation of the results. The third group, the lake morphometry parameters, are standard parameters for the outline of sampling programmes and for calculations of the physical extension of different key habitats in the system. The fourth group, the ecosystem of the lake, includes physical, chemical and biological parameters required for determination of the stratification pattern, light climate, influence from the terrestrial ecosystem of the catchment area, trophic status, distribution of key habitats, and presence of fish and rare fauna and flora in the lake. In the context of site investigation program, the parameters in these two groups will be used for budget calculations of the flow of energy and material in the system. The fifth group, finally, describes the degree on anthropogenic influence on the ecosystem and will in the context of site investigation programmes be used to judge eventual malfunctioning within the entire, or parts of, the lake ecosystem

  10. Postexposure Treatment and Animal Rabies, Ontario, 1958-2000

    OpenAIRE

    Nunan, Christopher P.; Tinline, Rowland R.; Honig, Janet M.; Ball, David G. A.; Hauschildt, Peggy; LeBer, Charles A.

    2002-01-01

    This paper investigates the relationship between animal rabies and postexposure treatment (PET) in Ontario by examining the introduction of human diploid cell vaccine (HDCV) in 1980 and the initiation of an oral rabies vaccination program for wildlife in 1989. Introducing HDCV led to an immediate doubling of treatments. Both animal rabies and human treatments declined rapidly after the vaccination program was introduced, but human treatments have leveled off at approximately 1,000 per year.

  11. Director, Laboratory Animal Care and Use Section

    Data.gov (United States)

    Federal Laboratory Consortium — The NIAMS Laboratory Animal Care and Use Section (LACU) provides support to all NIAMS Intramural Research Program (IRP) Branches and Laboratories using animals. The...

  12. Investigating the role of state and local health departments in addressing public health concerns related to industrial food animal production sites.

    Directory of Open Access Journals (Sweden)

    Jillian P Fry

    Full Text Available OBJECTIVES: Evidence of community health concerns stemming from industrial food animal production (IFAP facilities continues to accumulate. This study examined the role of local and state health departments in responding to and preventing community-driven concerns associated with IFAP. METHODS: We conducted semi-structured qualitative interviews with state and county health department staff and community members in eight states with high densities or rapid growth of IFAP operations. We investigated the extent to which health concerns associated with IFAP sites are reported to health departments, the nature of health departments' responses, and barriers to involvement. RESULTS: Health departments' roles in these matters are limited by political barriers, lack of jurisdiction, and finite resources, expertise, and staff. Community members reported difficulties in engaging health departments on these issues. CONCLUSIONS: Our investigation suggests that health departments frequently lack resources or jurisdiction to respond to health concerns related to IFAP sites, resulting in limited engagement. Since agencies with jurisdiction over IFAP frequently lack a health focus, increased health department engagement may better protect public health.

  13. Suppression of Locomotor Activity in Female C57Bl/6J Mice Treated with Interleukin-1β: Investigating a Method for the Study of Fatigue in Laboratory Animals.

    Directory of Open Access Journals (Sweden)

    David R Bonsall

    Full Text Available Fatigue is a disabling symptom in patients with multiple sclerosis and Parkinson's Disease, and is also common in patients with traumatic brain injury, cancer, and inflammatory disorders. Little is known about the neurobiology of fatigue, in part due to the lack of an approach to induce fatigue in laboratory animals. Fatigue is a common response to systemic challenge by pathogens, a response in part mediated through action of the pro-inflammatory cytokine interleukin-1 beta (IL-1β. We investigated the behavioral responses of mice to IL-1β. Female C57Bl/6J mice of 3 ages were administered IL-1β at various doses i.p. Interleukin-1β reduced locomotor activity, and sensitivity increased with age. Further experiments were conducted with middle-aged females. Centrally administered IL-1β dose-dependently reduced locomotor activity. Using doses of IL-1β that caused suppression of locomotor activity, we measured minimal signs of sickness, such as hyperthermia, pain or anhedonia (as measured with abdominal temperature probes, pre-treatment with the analgesic buprenorphine and through sucrose preference, respectively, all of which are responses commonly reported with higher doses. We found that middle-aged orexin-/- mice showed equivalent effects of IL-1β on locomotor activity as seen in wild-type controls, suggesting that orexins are not necessary for IL-1β -induced reductions in wheel-running. Given that the availability and success of therapeutic treatments for fatigue is currently limited, we examined the effectiveness of two potential clinical treatments, modafinil and methylphenidate. We found that these treatments were variably successful in restoring locomotor activity after IL-1β administration. This provides one step toward development of a satisfactory animal model of the multidimensional experience of fatigue, a model that could allow us to determine possible pathways through which inflammation induces fatigue, and could lead to novel

  14. Resiliency Training in Indian Children: A Pilot Investigation of the Penn Resiliency Program

    OpenAIRE

    Aruna Sankaranarayanan; Chandrika Cycil

    2014-01-01

    This paper examines the effectiveness of the Penn Resiliency Program (PRP) in an urban Indian setting. The PRP is a program to prevent depression in early adolescence and has proved successful in changing children’s attributional style of life events. While the program has been successful in preventing symptoms of depression in Western populations, the current study explored whether this program could be effective with an Indian sample. The aim of the current study was twofold; first, to stu...

  15. An Investigation of Factors Related to Self-Efficacy for Java Programming among Engineering Students

    Science.gov (United States)

    Askar, Petek; Davenport, David

    2009-01-01

    The purpose of this study was to examine the factors related to self-efficacy for Java programming among first year engineering students. An instrument assessing Java programming self-efficacy was developed from the computer programming self-efficacy scale of Ramalingam & Wiedenbeck. The instrument was administered at the beginning of the course…

  16. The Solar-Stellar Connection (NAG5-6124: SOHO Guest Investigator Program)

    Science.gov (United States)

    Ayres, Thomas R.

    1997-01-01

    The following is a final report from the SOHO Guest Investigator program to use the SUMER far-UV spectrometer to obtain imaging spectroscopy in support of the goals of the so-called "solar-stellar connection." In particular, a major emphasis was utilization of the long-slit time-resolved maps of the solar surface in bright far-UV emission lines to deduce how particular aspects of the temporally and spatially averaged line profiles trace back to individual structural features of the magnetically disturbed outer atmosphere; to help interpret the unresolved line profiles from high quality stellar observations (say, with the Space Telescope Imaging Spectrograph). The researchers served two tours of duty in the SOHO Operations Center as SUMER planners, during which time we conducted an extensive series of observing programs. These can be divided into three general categories: surface mapping, translimb spectroscopy, and active region diagnostics. We have analyzed some of the large volumes of data to the point where we have presented them in poster papers, and in invited papers at national and international meetings. Listed below are the titles of the preliminary publications we have written, including brief abstracts to indicate the main results. (1) Chromospheric structure and Dynamics-- Observations -- The chromosphere is a highly structured dynamic 'layer' of the solar outer atmosphere. Here, not only are the effects of mechanical heating first evident (moving upward in altitude from the deep photosphere), but also the amount of nonradiative energy deposited is far greater than in the albeit much hotter overlying transition region and corona. Further, the chromosphere is by far the thickest zone of the solar atmosphere with respect to the pressure scale height. A major goal of stellar astrophysics is to understand how the chromosphere is heated and why it adopts its peculiar structure. A cursory examination of solar filtergrams and high-resolution movies demonstrates

  17. LJUNGSKILE 1.0 A Computer Program for Investigation of Uncertainties in Chemical Speciation

    International Nuclear Information System (INIS)

    In analysing the long-term safety of nuclear waste disposal, there is a need to investigate uncertainties in chemical speciation calculations. Chemical speciation is of importance in evaluating the solubility of radionuclides, the chemical degradation of engineering materials, and chemical processes controlling groundwater composition. The uncertainties in chemical speciation may for instance be related to uncertainties in thermodynamic data, the groundwater composition, or the extrapolation to the actual temperature and ionic strength. The magnitude of such uncertainties and its implications are seldom explicitly evaluated in any detail. Commonly available chemical speciation programmes normally do not have a build-in option to include uncertainty ranges. The program developed within this project has the capability of incorporating uncertainty ranges in speciation calculations and can be used for graphical presentation of uncertainty ranges for dominant species. The program should be regarded as a starting point for assessing uncertainties in chemical speciation, since it is not yet comprehensive in its capabilities. There may be limitations in its usefulness to address various geochemical problems. The LJUNGSKILE code allows the user to select two approaches: the Monte Carlo (MC) approach and the Latin Hypercube Sampling (LHS). LHS allows to produce a satisfactory statistics with a minimum of CPU time. It is, in general, possible to do a simple theoretical speciation calculation within seconds. There are, admittedly, alternatives to LHS and there is criticism towards the uncritical use of LHS output because commonly correlation between some of the input variables exists. LHS, like MC, is not capable to take these correlations into account. Such a correlation can, i.e. exist between the pH of a solution and the partial pressure of CO2: higher pH solutions may absorb larger amounts of CO2 and can reduce the CO2 partial pressure. It is therefore of advantage to

  18. Investigate Methods to Decrease Compilation Time-AX-Program Code Group Computer Science R& D Project

    Energy Technology Data Exchange (ETDEWEB)

    Cottom, T

    2003-06-11

    Large simulation codes can take on the order of hours to compile from scratch. In Kull, which uses generic programming techniques, a significant portion of the time is spent generating and compiling template instantiations. I would like to investigate methods that would decrease the overall compilation time for large codes. These would be methods which could then be applied, hopefully, as standard practice to any large code. Success is measured by the overall decrease in wall clock time a developer spends waiting for an executable. Analyzing the make system of a slow to build project can benefit all developers on the project. Taking the time to analyze the number of processors used over the life of the build and restructuring the system to maximize the parallelization can significantly reduce build times. Distributing the build across multiple machines with the same configuration can increase the number of available processors for building and can help evenly balance the load. Becoming familiar with compiler options can have its benefits as well. The time improvements of the sum can be significant. Initial compilation time for Kull on OSF1 was {approx} 3 hours. Final time on OSF1 after completion is 16 minutes. Initial compilation time for Kull on AIX was {approx} 2 hours. Final time on AIX after completion is 25 minutes. Developers now spend 3 hours less waiting for a Kull executable on OSF1, and 2 hours less on AIX platforms. In the eyes of many Kull code developers, the project was a huge success.

  19. Summary of U.S. Geological Survey and City of Albuquerque hydrologic investigations program

    Energy Technology Data Exchange (ETDEWEB)

    McAda, D. [Geological Survey, Albuquerque, NM (United States). Water Resources Div.

    1995-12-31

    The US Geological Survey and Albuquerque have been cooperating in data collection programs and interpretive studies since 1982. The paper presents summaries on recently completed and ongoing projects, detailing the objectives, principal investigator, period of the project, and reports released or reports in progress on each study. Project names are: Ground-water-level monitoring network in the Albuquerque Basin; Water budget of the Rio Grande flood plain in the Albuquerque area; Modeling of groundwater flow in the Albuquerque Basin; Continuation of ground water flow modeling in the Albuquerque Basin; Evaluation of methods to quantify the hydrologic relations between the Rio Grande and the Santa Fe Group aquifer system, near Albuquerque; Aquifer compaction and land subsidence in the Albuquerque, NM area; Aquifer test at the Griegos Well Field, Albuquerque, NM; Quality of urban stormwater runoff; Rio Grande water quality; Determining accurate concentrations and loads of trace elements and other selected chemical constituents in the Rio Grande, Albuquerque, NM; Digital geophysical-log data base; and Water quality data for the Albuquerque Basin.

  20. Biodiesel production from inedible animal tallow and an experimental investigation of its use as alternative fuel in a direct injection diesel engine

    Energy Technology Data Exchange (ETDEWEB)

    Oener, Cengiz [Technical Education Faculty, Automotive Division, Firat University, 23119 Elazig (Turkey); Altun, Sehmus [Technical Education Faculty, Automotive Division, Batman University, 72060 Batman (Turkey)

    2009-10-15

    In this study, a substitute fuel for diesel engines was produced from inedible animal tallow and its usability was investigated as pure biodiesel and its blends with petroleum diesel fuel in a diesel engine. Tallow methyl ester as biodiesel fuel was prepared by base-catalyzed transesterification of the fat with methanol in the presence of NaOH as catalyst. Fuel properties of methyl ester, diesel fuel and blends of them (5%, 20% and 50% by volume) were determined. Viscosity and density of fatty acid methyl ester have been found to meet ASTM D6751 and EN 14214 specifications. Viscosity and density of tallow methyl esters are found to be very close to that of diesel. The calorific value of biodiesel is found to be slightly lower than that of diesel. An experimental study was carried out in order to investigate of its usability as alternative fuel of tallow methyl ester in a direct injection diesel engine. It was observed that the addition of biodiesel to the diesel fuel decreases the effective efficiency of engine and increases the specific fuel consumption. This is due to the lower heating value of biodiesel compared to diesel fuel. However, the effective engine power was comparable by biodiesel compared with diesel fuel. Emissions of carbon monoxide (CO), oxides of nitrogen (NO{sub x}), sulphur dioxide (SO{sub 2}) and smoke opacity were reduced around 15%, 38.5%, 72.7% and 56.8%, respectively, in case of tallow methyl esters (B100) compared to diesel fuel. Besides, the lowest CO, NO{sub x} emissions and the highest exhaust temperature were obtained for B20 among all other fuels. The reductions in exhaust emissions made tallow methyl esters and its blends, especially B20 a suitable alternative fuel for diesel and thus could help in controlling air pollution. Based on this study, animal tallow methyl esters and its blends with petroleum diesel fuel can be used a substitute for diesel in direct injection diesel engines without any engine modification. (author)

  1. Animal Bites

    Science.gov (United States)

    ... and complications from bites Never pet, handle, or feed unknown animals Leave snakes alone Watch your children closely around animals Vaccinate your cats, ferrets, and dogs against rabies Spay or neuter ...

  2. Animal Bites

    Science.gov (United States)

    Wild animals usually avoid people. They might attack, however, if they feel threatened, are sick, or are protecting their ... or territory. Attacks by pets are more common. Animal bites rarely are life-threatening, but if they ...

  3. Animal Farm

    Institute of Scientific and Technical Information of China (English)

    徐蓉蓉

    2015-01-01

    This essay first introduce the background of Animal Farm and a brief introduction of the author.Then it discuss three thesis about this novel and briefly discussed about it.At last it give highly review on Animal Farm.

  4. Animal Farm

    Institute of Scientific and Technical Information of China (English)

    徐蓉蓉

    2015-01-01

    This essayfirst introduce the background of Animal Farm and a brief introduction of the author.Then it discuss three thesis about this novel and briefly discussed about it.At last it give highly review on Animal Farm.

  5. Animal ethics

    OpenAIRE

    Palmer, Clare; Sandøe, Peter

    2011-01-01

    This chapter describes and discusses different views concerning our duties towards animals. First, we explain why it is necessary to engage in thinking about animal ethics and why it is not enough to rely on feelings alone. Secondly, we present and discuss five different kinds of views about the nature of our duties to animals. They are: contractarianism, utilitarianism, the animal rights view, contextual views, and a respect for nature view. Finally, we briefly consider whether it is possibl...

  6. A Large Sample Evaluation of a Court-Mandated Batterer Intervention Program: Investigating Differential Program Effect for African American and Caucasian Men

    Science.gov (United States)

    Buttell, Frederick P.; Carney, Michelle Mohr

    2006-01-01

    Objective: The purpose of the present study was to (a) evaluate a 26-week batterer intervention program by investigating changes in psychological variables related to abuse (i.e., truthfulness, violence, lethality, control, alcohol use, drug use, and stress coping abilities) between pretreatment and posttreatment assessments in a large sample of…

  7. Animal Deliberation

    NARCIS (Netherlands)

    Driessen, C.P.G.

    2014-01-01

    While much has been written on environmental politics on the one hand, and animal ethics and welfare on the other, animal politics, as the interface of the two, is underexamined. There are key political implications in the increase of animal protection laws, the rights of nature, and political parti

  8. Animal models

    DEFF Research Database (Denmark)

    Gøtze, Jens Peter; Krentz, Andrew

    2014-01-01

    In this issue of Cardiovascular Endocrinology, we are proud to present a broad and dedicated spectrum of reviews on animal models in cardiovascular disease. The reviews cover most aspects of animal models in science from basic differences and similarities between small animals and the human...

  9. Investigating Positive Psychology Approaches in Case Management and Residential Programming with Incarcerated Youth

    Science.gov (United States)

    Cross, Lara E.; Morrison, William; Peterson, Patricia; Domene, Jose F.

    2012-01-01

    This article examines how a rural Canadian secure custody facility for youth implemented positive psychology principles in its case management protocols and residential programming. A directed content analysis design was utilized to identify specific factors of positive psychology in the facility's policy and programming manual, as well as in…

  10. Aquatic Species Program Review: Proceedings of the March 1983 Principal Investigators Meeting

    Energy Technology Data Exchange (ETDEWEB)

    1983-06-01

    The Aquatic Species Program (ASP) addresses the utilization of plant biomass that naturally occurs in wetland or submerged areas. Processes are being developed through this program to make use of such aquatic species, capitalizing on their inherent capacity for rapid growth as well as their extraordinary chemical compositions.

  11. Engagement Theory in Action: An Investigation of Athletic Training Program Directors

    Science.gov (United States)

    Peer, Kimberly S.

    2007-01-01

    Objective: To examine the use of good practice indicators by athletic training program directors and to provide a theoretical framework using engagement theory, a learner-centered process focusing on program improvement through continuous planning and evaluation, as a foundation for implementing good practices in athletic training education…

  12. Beyond Cognitive Increase: Investigating the Influence of Computer Programming on Perception and Application of Mathematical Skills

    Science.gov (United States)

    Rich, Peter J.; Bly, Neil; Leatham, Keith R.

    2014-01-01

    This study aimed to provide first-hand accounts of the perceived long-term effects of learning computer programming on a learner's approach to mathematics. These phenomenological accounts, garnered from individual interviews of seven different programmers, illustrate four specific areas of interest: (1) programming provides context for many…

  13. Counseling Skills Pre-Practicum Training at Guidance and Counseling Undergraduate Programs: A Qualitative Investigation

    Science.gov (United States)

    Aladag, Mine

    2013-01-01

    This study was aimed to describe counseling skills pre-practicum training at guidance and counseling undergraduate programs in Turkey. A descriptive study was conducted based upon qualitative data. The research group of this study consisted of 11 guidance and counseling undergraduate programs voluntarily participate into study. The Survey Form…

  14. Investigating Stakeholder Attitudes and Opinions on School-Based Human Papillomavirus Vaccination Programs

    Science.gov (United States)

    Nodulman, Jessica A.; Starling, Randall; Kong, Alberta S.; Buller, David B.; Wheeler, Cosette M.; Woodall, W. Gill

    2015-01-01

    Background: In several countries worldwide, school-based human papillomavirus (HPV) vaccination programs have been successful; however, little research has explored US stakeholders' acceptance toward school-based HPV vaccination programs. Methods: A total of 13 focus groups and 12 key informant interviews (N?=?117; 85% females; 66% racial/ethnic…

  15. An investigation of potential success factors for an introductory model-driven programming course

    DEFF Research Database (Denmark)

    Bennedsen, Jens; Caspersen, Michael Edelgaard

    2005-01-01

    In order to improve the course design of a CS1 model-driven programming course we study potential indicators of success for such a course. We explain our specific interpretation of objects-first. Of eight potential indicators of success, we have found only two to be significant at a 95% confidence...... on the success factors for objects-first programming....

  16. Entry, Descent, Landing Animation (Animation)

    Science.gov (United States)

    2005-01-01

    [figure removed for brevity, see original site] Click on the image for Entry, Descent, Landing animation This animation illustrates the path the Stardust return capsule will follow once it enters Earth's atmosphere.

  17. Thinking with animals

    OpenAIRE

    2015-01-01

    they also enlist them to symbolize, dramatize, and illuminate aspects of humans' experience and fantasy. Humans merge with animals in stories, films, philosophical speculations, and scientific treatises. In their performance on many stages and in different ways, animals move us to think." "Essays in the book investigate the changing patterns of anthropomorphism across different time periods and settings, as well as their transformative effects, both figuratively and literally, upon animals, h...

  18. Resiliency Training in Indian Children: A Pilot Investigation of the Penn Resiliency Program

    Directory of Open Access Journals (Sweden)

    Aruna Sankaranarayanan

    2014-04-01

    Full Text Available This paper examines the effectiveness of the Penn Resiliency Program (PRP in an urban Indian setting. The PRP is a program to prevent depression in early adolescence and has proved successful in changing children’s attributional style of life events. While the program has been successful in preventing symptoms of depression in Western populations, the current study explored whether this program could be effective with an Indian sample. The aim of the current study was twofold; first, to study the attributional style of early adolescents in India and identify negative effects (if any and second, to gain insights in using the PRP as a tool to change explanatory styles in Indian children. A total of 58 children participated in the study (Intervention group n = 29 and Control group n = 29. An Analysis of Covariance comparing post-test scores on Children’s Attributional Style Questionnaire (CASQ while controlling for baseline scores indicated that children in the intervention group exhibited a significant reduction in pessimistic explanatory style and an increase in optimistic orientation compared to children in the control group. This indicates that the program was effective in changing negative attribution styles among upper-class Indian school children. Future work may look into the longer impact of the program as well as further considerations into adapting the program for a middle class population.

  19. Resiliency training in Indian children: a pilot investigation of the Penn Resiliency Program.

    Science.gov (United States)

    Sankaranarayanan, Aruna; Cycil, Chandrika

    2014-04-01

    This paper examines the effectiveness of the Penn Resiliency Program (PRP) in an urban Indian setting. The PRP is a program to prevent depression in early adolescence and has proved successful in changing children's attributional style of life events. While the program has been successful in preventing symptoms of depression in Western populations, the current study explored whether this program could be effective with an Indian sample. The aim of the current study was twofold; first, to study the attributional style of early adolescents in India and identify negative effects (if any) and second, to gain insights in using the PRP as a tool to change explanatory styles in Indian children. A total of 58 children participated in the study (Intervention group n = 29 and Control group n = 29). An Analysis of Covariance comparing post-test scores on Children's Attributional Style Questionnaire (CASQ) while controlling for baseline scores indicated that children in the intervention group exhibited a significant reduction in pessimistic explanatory style and an increase in optimistic orientation compared to children in the control group. This indicates that the program was effective in changing negative attribution styles among upper-class Indian school children. Future work may look into the longer impact of the program as well as further considerations into adapting the program for a middle class population. PMID:24739766

  20. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    The Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, manages archaeological resources on the Savannah River Site (SRS). An ongoing research program provides the theoretical, methodological, and empirical basis for assessing site significance within the compliance process specified by law. The SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research, and public education activities of the SRARP during Fiscal Year 1994.

  1. Dissolved Oxygen Sensor in Animal-Borne Instruments: An Innovation for Monitoring the Health of Oceans and Investigating the Functioning of Marine Ecosystems.

    Directory of Open Access Journals (Sweden)

    Frederic Bailleul

    Full Text Available The current decline in dissolved oxygen concentration within the oceans is a sensitive indicator of the effect of climate change on marine environment. However the impact of its declining on marine life and ecosystems' health is still quite unclear because of the difficulty in obtaining in situ data, especially in remote areas, like the Southern Ocean (SO. Southern elephant seals (Mirounga leonina proved to be a relevant alternative to the traditional oceanographic platforms to measure physical and biogeochemical structure of oceanic regions rarely observed. In this study, we use a new stage of development in biologging technology to draw a picture of dissolved oxygen concentration in the SO. We present the first results obtained from a dissolved oxygen sensor added to Argos CTD-SRDL tags and deployed on 5 female elephant seals at Kerguelen. From October 2010 and October 2011, 742 oxygen profiles associated with temperature and salinity measurements were recorded. Whether a part of the data must be considered cautiously, especially because of offsets and temporal drifts of the sensors, the range of values recorded was consistent with a concomitant survey conducted from a research vessel (Keops-2 project. Once again, elephant seals reinforced the relationship between marine ecology and oceanography, delivering essential information about the water masses properties and the biological status of the Southern Ocean. But more than the presentation of a new stage of development in animal-borne instrumentation, this pilot study opens a new field of investigation in marine ecology and could be enlarged in a near future to other key marine predators, especially large fish species like swordfish, tuna or sharks, for which dissolved oxygen is expected to play a crucial role in distribution and behaviour.

  2. Dissolved Oxygen Sensor in Animal-Borne Instruments: An Innovation for Monitoring the Health of Oceans and Investigating the Functioning of Marine Ecosystems.

    Science.gov (United States)

    Bailleul, Frederic; Vacquie-Garcia, Jade; Guinet, Christophe

    2015-01-01

    The current decline in dissolved oxygen concentration within the oceans is a sensitive indicator of the effect of climate change on marine environment. However the impact of its declining on marine life and ecosystems' health is still quite unclear because of the difficulty in obtaining in situ data, especially in remote areas, like the Southern Ocean (SO). Southern elephant seals (Mirounga leonina) proved to be a relevant alternative to the traditional oceanographic platforms to measure physical and biogeochemical structure of oceanic regions rarely observed. In this study, we use a new stage of development in biologging technology to draw a picture of dissolved oxygen concentration in the SO. We present the first results obtained from a dissolved oxygen sensor added to Argos CTD-SRDL tags and deployed on 5 female elephant seals at Kerguelen. From October 2010 and October 2011, 742 oxygen profiles associated with temperature and salinity measurements were recorded. Whether a part of the data must be considered cautiously, especially because of offsets and temporal drifts of the sensors, the range of values recorded was consistent with a concomitant survey conducted from a research vessel (Keops-2 project). Once again, elephant seals reinforced the relationship between marine ecology and oceanography, delivering essential information about the water masses properties and the biological status of the Southern Ocean. But more than the presentation of a new stage of development in animal-borne instrumentation, this pilot study opens a new field of investigation in marine ecology and could be enlarged in a near future to other key marine predators, especially large fish species like swordfish, tuna or sharks, for which dissolved oxygen is expected to play a crucial role in distribution and behaviour. PMID:26200780

  3. Animals in the Classroom

    Science.gov (United States)

    Roy, Ken

    2011-01-01

    Use of animals in middle school science classrooms is a curriculum component worthy of consideration, providing proper investigation and planning are addressed. A responsible approach to this action, including safety, must be adopted for success. In this month's column, the author provides some suggestions on incorporating animals into the…

  4. Endangered Animals. Second Grade.

    Science.gov (United States)

    Popp, Marcia

    This second grade teaching unit centers on endangered animal species around the world. Questions addressed are: What is an endangered species? Why do animals become extinct? How do I feel about the problem? and What can I do? Students study the definition of endangered species and investigate whether it is a natural process. They explore topics…

  5. Animal Shelter

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Beijing activist Zhang Luping gives up a lucrative business career to provide a home for stray and abandoned pets "I have never been married, but I have I hundreds of children," said Zhang Luping, founder of the Beijing Human and Animal Environment Education Center (the Animal Center). "God sent me to this planet and gave me the mission of taking care of helpless and homeless dogs and cats. I will never let Him down." The Animal Center, one of a few non-

  6. Investigating the Effects of Professional Practice Program on Teacher Education Students' Ability to Articulate Educational Philosophy

    Science.gov (United States)

    Weshah, Hani A.

    2013-01-01

    The purpose of this study was to investigate the changes in pre-service student teachers' ability to articulate a philosophy education during the field experience. Educational philosophy change for the participants (77) was measured by using Jersin's scale. Evaluations of scores involved comparison of pre and post the training program.…

  7. An Investigation of the Relationships between Mathematics and Music Skills of Students Participating in Successful High School Instrumental Music Programs

    Science.gov (United States)

    Deppe, Scott

    2012-01-01

    This exploratory phenomenological study was designed to investigate the relationships between mathematics and music skills of students participating in successful high school instrumental music programs. The participants of this study were purposefully selected and included one math educator or math department chairperson and the band or orchestra…

  8. Investigation of Pre-Service Teachers' Opinions about Science in Terms of the Basic Elements of the Education Program

    Science.gov (United States)

    Sengul, Ozge Aydin

    2016-01-01

    The purpose of the current study is to investigate the pre-service teachers' opinions about science within the context of the basic elements of the education program, such as objectives, content, learning-teaching process and evaluation. The study was designed as a case study, one of the qualitative research methods. The participants of the study…

  9. Animal ethics

    DEFF Research Database (Denmark)

    Palmer, Clare; Sandøe, Peter

    2011-01-01

    the nature of our duties to animals. They are: contractarianism, utilitarianism, the animal rights view, contextual views, and a respect for nature view. Finally, we briefly consider whether it is possible to combine elements from the presented views, and how to make up one’s mind.......This chapter describes and discusses different views concerning our duties towards animals. First, we explain why it is necessary to engage in thinking about animal ethics and why it is not enough to rely on feelings alone. Secondly, we present and discuss five different kinds of views about...

  10. 75 FR 33576 - Animal Traceability; Public Meetings

    Science.gov (United States)

    2010-06-14

    ... Animal and Plant Health Inspection Service Animal Traceability; Public Meetings AGENCY: Animal and Plant... traceability. The meetings are being organized by the Animal and Plant Health Inspection Service. Additional...: Mr. Neil Hammerschmidt, Program Manager, Animal Disease Traceability, VS, APHIS, 4700 River Road...

  11. Pilot study investigating the utility of a specialized online symptom management program for individuals with myalgic encephalomyelitis/chronic fatigue syndrome as compared to an online meditation program

    Directory of Open Access Journals (Sweden)

    Arroll MA

    2014-09-01

    Full Text Available Megan A Arroll, Elizabeth A Attree, Claire L Marshall, Christine P DanceyChronic Illness Research Team, School of Psychology, University of East London, London, UKBackground: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS is a long-term, debilitating condition that impacts numerous areas of individuals' lives. The two predominant treatment options for ME/CFS are cognitive behavioral therapy and graded exercise therapy; however, many people have found these techniques unacceptable or even damaging. This pilot study aimed to evaluate the utility of a specialized online symptom management program for ME/CFS in comparison to an online meditation program in an effort to ascertain whether this tool could be a further option for those with ME/CFS.Methods: This experimental design consisted of two interventions: a specialized online symptoms management program (N=19 and a control intervention based on an online meditation website (N=9. A battery of questionnaires, including measures of multidimensional fatigue, illness-specific symptoms, perceived control, and mindful awareness, were completed before the participants commenced use of the programs and following 8 weeks' use.Results: Significant differences were found in the areas of chance and powerful others' locus of control, and sleeping difficulties, but not in ME/CFS symptomatology overall.Conclusion: The specialized online program described in this study warrants further investigation, as it appears to influence perceived control and key ME/CFS symptoms over time.Keywords: ME/CFS, perceived control, sleep, outcomes, online intervention

  12. Investigating the Effect of Implementing the School Based Health Promotion Program on Students’ Mental Health

    Directory of Open Access Journals (Sweden)

    Abdollatif Esmaeili

    2011-01-01

    Full Text Available Introduction: The “school- based health program” is implemented in schools all over the country with the purpose of preventing substance abuse, high-risk behaviors, and violence. The current study aimed at evaluating the effectiveness of this program in enhancing some of the health indicators of the students participating in this program. Methods: In this cross- sectional study, based on the Krejcie and Morgan table, 400 students (4 groups- 2cases and 2 controls- each including 100 people from both male and female genders were selected through stratified and stage random sampling. The data gathering tools were the “General Health Questionnaire”, Rosenberg Self Esteem Inventory, Oxford Happiness Questionnaire, Satisfied with Life Scale. The data were analyzed using SPSS 13 software and through descriptive statistics and paired t test. Results: There were no statistically significant differences between General Health, Self esteem, Happiness and Satisfied with Life mean scores of case and control groups. However, the differences between the mean scores of the two groups in educational performance were significant (P=0.005. Conclusion: General findings of this study indicate that education presented to students via school-based health program has not been effective in enhancing their mental health. Therefore, to improve the effectiveness of this program, it is suggested that the educational methods of this program be revised.

  13. Small Animal Retinal Imaging

    Science.gov (United States)

    Choi, WooJhon; Drexler, Wolfgang; Fujimoto, James G.

    Developing and validating new techniques and methods for small animal imaging is an important research area because there are many small animal models of retinal diseases such as diabetic retinopathy, age-related macular degeneration, and glaucoma [1-6]. Because the retina is a multilayered structure with distinct abnormalities occurring in different intraretinal layers at different stages of disease progression, there is a need for imaging techniques that enable visualization of these layers individually at different time points. Although postmortem histology and ultrastructural analysis can be performed for investigating microscopic changes in the retina in small animal models, this requires sacrificing animals, which makes repeated assessment of the same animal at different time points impossible and increases the number of animals required. Furthermore, some retinal processes such as neurovascular coupling cannot be fully characterized postmortem.

  14. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-01

    A cooperative agreement with the United States Department of Energy provides the necessary funding for the Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, to render services required under federal law for the protection and management of archaeological resources on the Savannah River Site (SRS). Because the significance of archaeological resources is usually determined by research potential, the SRARP is guided by research objectives. An ongoing research program provides the theoretical, methodological, and empirical basis for assessing site significance within the compliance process specified by law. In accordance with the spirit of the law, the SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research, and public education activities of the SRARP during Fiscal Year 1993.

  15. Investigation of the correlates and effectiveness of a prison-based wellness program.

    Science.gov (United States)

    Clouse, Monica L; Mannino, David; Curd, Philip R

    2012-07-01

    In 2006, a comprehensive wellness intervention, titled Wellness Works, was implemented in an incarcerated male population at a 200-bed facility in LaGrange, Kentucky. The purpose of this study was to determine health risk factors and benefits of program participation by analyzing data from a pre-/post-participation health risk assessment (HRA). In total, 448 inmates completed the pre- HRA and 177 (40%) completed the post- HRA. Among program completers, two of the six measured domains (smoking and depression) showed significant improvement at the post- HRA while the other domains (exercise, nutrition, stress, and dental hygiene) did not show significant changes. Overall, this study shows positive signs of improving the health of the incarcerated population with this wellness program, but also points to the need for a controlled study. PMID:22610348

  16. Animal Detectives

    Science.gov (United States)

    Mulvey, Bridget; Warnock, Carly

    2015-01-01

    During a two-week inquiry-based 5E learning cycle unit, children made observations and inferences to guide their explorations of animal traits and habitats (Bybee 2014). The children became "animal detectives" by studying a live-feed webcam and digital images of wolves in their natural habitat, reading books and online sources about…

  17. Kindergarten Animation

    Science.gov (United States)

    Hinshaw, Craig

    2012-01-01

    Animation is one of the last lessons that come to mind when thinking of kindergarten art. The necessary understanding of sequencing, attention to small, often detailed drawings, and the use of technology all seem more suitable to upper elementary. With today's emphasis on condensing and integrating curriculum, consider developing animation lessons…

  18. Animal cytomegaloviruses.

    OpenAIRE

    Staczek, J.

    1990-01-01

    Cytomegaloviruses are agents that infect a variety of animals. Human cytomegalovirus is associated with infections that may be inapparent or may result in severe body malformation. More recently, human cytomegalovirus infections have been recognized as causing severe complications in immunosuppressed individuals. In other animals, cytomegaloviruses are often associated with infections having relatively mild sequelae. Many of these sequelae parallel symptoms associated with human cytomegalovir...

  19. ANIMAL code

    International Nuclear Information System (INIS)

    This report describes ANIMAL, a two-dimensional Eulerian magnetohydrodynamic computer code. ANIMAL's physical model also appears. Formulated are temporal and spatial finite-difference equations in a manner that facilitates implementation of the algorithm. Outlined are the functions of the algorithm's FORTRAN subroutines and variables

  20. An Investigation of Multi-core (Single-Chip Multiprocessor) Programming Languages

    OpenAIRE

    Ibánes Verón, Pablo

    2011-01-01

    The goal of this thesis is to overview the different multi-core programming models and technologies. Nowadays multi-core systems are more and more popular. Personal computers usually are based on multi-core technology since some years ago so it is needed some technologies for implementing it. In this thesis, we have studied several models and technologies of multi-core programming. We have also studied and presented a comparison of the models and technologies. Furthermore, we have shown the i...

  1. A mentor training program improves mentoring competency for researchers working with early-career investigators from underrepresented backgrounds.

    Science.gov (United States)

    Johnson, Mallory O; Gandhi, Monica

    2015-08-01

    Mentoring is increasingly recognized as a critical element in supporting successful careers in academic research in medicine and related disciplines, particularly for trainees and early career investigators from underrepresented backgrounds. Mentoring is often executed ad hoc; there are limited programs to train faculty to become more effective mentors, and the few that exist have a dearth of empirical support of their impact. In 2013, we recruited 34 faculty from across the US engaged in HIV-related clinical research to participate in a 2-day Mentoring the Mentors workshop. The workshop included didactic and interactive content focused on a range of topics, such as mentor-mentee communication, leadership styles, emotional intelligence, understanding the impact of diversity (unconscious bias, microaggressions, discrimination, tokenism) for mentees, and specific tools and techniques for effective mentoring. Pre- and post-workshop online evaluations documented high rates of satisfaction with the program and statistically significant improvements in self-appraised mentoring skills (e.g. addressing diversity in mentoring, communication with mentees, aligning mentor-mentee expectations), as assessed via a validated mentoring competency tool. This is the first mentoring training program focused on enhancing mentors' abilities to nurture investigators of diversity, filling an important gap, and evaluation results offer support for its effectiveness. Results suggest a need for refinement and expansion of the program and for more comprehensive, long-term evaluation of distal mentoring outcomes for those who participate in the program. PMID:25274417

  2. An Investigation of Self-Regulatory Mechanisms in Learning to Program Visual Basic

    Science.gov (United States)

    Kuo, Feng-Yang; Wu, Wen-Hsiung; Lin, Cathy S.

    2013-01-01

    Today, information technology (IT) has permeated virtually every aspect of our society and the learning of software programming is becoming increasingly important to the creation and maintenance of the IT infrastructure critical to our daily life. In this article, we report the results of a study that demonstrates how the self-regulation paradigm…

  3. Programmed Lab Experiments for Biochemical Investigation of Quorum-Sensing Signal Molecules in Rhizospheric Soil Bacteria

    Science.gov (United States)

    Nievas, Fiorela L.; Bogino, Pablo C.; Giordano, Walter

    2016-01-01

    Biochemistry courses in the Department of Molecular Biology at the National University of Río Cuarto, Argentina, are designed for undergraduate students in biology, microbiology, chemistry, agronomy, and veterinary medicine. Microbiology students typically have previous coursework in general, analytical, and organic chemistry. Programmed sequences…

  4. 77 FR 41316 - Federal Bureau of Investigation Anti-Piracy Warning Seal Program

    Science.gov (United States)

    2012-07-13

    ... September 7, 2011 (76 FR 55332), regarding the FBI APW Seal Program. In this regulation, the FBI extends... APW Seal and undermine the effectiveness of the anti-piracy message and the FBI's reputation; and that... more likely, this concern is overshadowed by the value of ] increasing public awareness of...

  5. Soil Investigations. Grade 3 Science. Maryland School Performance Assessment Program (MSPAP): Resource Library. Public Release Task.

    Science.gov (United States)

    Maryland State Dept. of Education. Baltimore. Div. of Planning, Results and Information Management.

    One component of the Maryland School Performance Program (MSPAP) is the state's performance-based assessments, criterion-referenced tests that require students to apply what they know and can do to solve problems and display other higher-order thinking skills. This document helps parents, teachers, students, and other citizens understand the tasks…

  6. Investigation of Placement Outcomes 3 Years after a Job Skills Training Program for Chronically Unemployed Adults

    Science.gov (United States)

    Tango, Robert A.; Kolodinsky, Pit

    2004-01-01

    This analysis of chronically unemployed job seekers after they completed a comprehensive job skills training program reveals dynamic interpersonal and intrapersonal characteristics that have an impact on job-finding success. Of primary interest in this study was the relationship between R. B. Cattell's (1988) second-order personality factors and…

  7. A Longitudinal Investigation of the Effects of a School Intervention Program on Children's Social Development.

    Science.gov (United States)

    Solomon, Daniel; And Others

    The Child Development Project (CDP) is a school-based program designed to foster children's social, ethical, and intellectual development through activities emphasizing cooperative learning, developmental discipline, social understanding, interpersonal helping, and prosocial values. The CDP was implemented in kindergarten through fourth grade by…

  8. Investigating a Developmentally Focused Youth Sports Program for Girls in Elementary Grades

    Science.gov (United States)

    Feathers, Rebecca Zarzycki

    2012-01-01

    The purpose of this study was to identify the impact the Girls on the Run (GOTR) program had on the New Castle County, Delaware, third, fourth, and fifth grade girls who participated in the spring 2011 season. Specifically, this study examined short-term changes in the participants as they related to self-esteem, body image, physical activity…

  9. 76 FR 31613 - NIOSH Fire Fighter Fatality Investigation and Prevention Program (FFFIPP)

    Science.gov (United States)

    2011-06-01

    ... stakeholders at those meetings was very valuable in providing insight into stakeholder needs and expectations... (NIOSH) of the Centers for Disease Control and Prevention (CDC) requests stakeholder input on the... (FFFIPP). NIOSH is seeking stakeholder input on the FFFIPP to ensure that the program is meeting the...

  10. Analysis on the investigation results of tick on animals in Ningbo%宁波市动物染蜱情况调查结果分析

    Institute of Scientific and Technical Information of China (English)

    马晓; 邵国文; 朱光锋; 徐荣

    2012-01-01

    目的:初步了解宁波市动物染蜱现状,为进一步建立蜱媒传染病综合监测系统.方法:采用现状调查方法,摸清宁波市家养和野外动物染蜱情况.结果:家养动物蜱感染率为29.94%,以狗染蜱最高;野外动物染蜱阳性率为6.67%;动物染蜱部位以肩背、耳廓和颈部等前半身最常见.结论:宁波市动物染蜱情况不容乐观,应引起公共卫生部门的重视.%Objective: To understand the status of tick on animals in Ningbo and establish the integrated monitoring system for preventing tick - borne diseases. Methods: The status of tick on domestic and wild animals was obtained by prevalence study. Results: The infection rate of tick on domestic animals was 29. 94% , and the highest rate was found in dogs;the positive rate of tick on wild animals was 6.67% ;the most common positions of tick on animals were shoulder, back, auricle and neck which belong to upper body. Conclusion: The public health department should pay attention to the status of tick on animals which was not optimistic.

  11. The Investigation of Physical Performance Status of Visually and Hearing Impaired Applying Judo Training Program

    Science.gov (United States)

    Karakoc, Onder

    2016-01-01

    It was aimed to investigate the physical performances of visually and hearing impaired doing judo training in this study. 32 male athletes, who were doing judo training, volunteer and, visually and hearing impaired, participated in this study. The investigation was applied to visually impaired (N = 12, mean ± SD; age: 25.75 ± 3.55 years, height:…

  12. Programs.

    Science.gov (United States)

    Community College Journal, 1996

    1996-01-01

    Includes a collection of eight short articles describing model community college programs. Discusses a literacy program, a mobile computer classroom, a support program for at-risk students, a timber-harvesting program, a multimedia presentation on successful women graduates, a career center, a collaboration with NASA, and an Israeli engineering…

  13. Wild Animals

    Institute of Scientific and Technical Information of China (English)

    宁静

    2005-01-01

    Many of us think that all wild animals are dangerous. In fact, very few of them will eat a man if he leaves them alone. If you meet a tiger, I'm sure you will run away, but even a tiger doesn't like meeting a man if it isn't hungry. Tigers only kill and eat man when they are too old to catch their food, such as sheep and other small animals. Some animals get frightened when they only smell a man. Some of themst and and look at a man for a short time before they run away.

  14. Research program: The investigation of heat transfer and fluid flow at low pressure

    Science.gov (United States)

    El-Genk, M. S.; Philbin, J. S.; Foushee, F. C.

    1986-04-01

    This paper gives an overview of a multiyear joint research program being conducted at the University of New Mexico (UNM) with support from Sandia National Laboratories and GA Technologies. This research focuses on heat removal and fluid dynamics in flow regimes characterized by low pressure and low Reynolds number. The program was motivated by a desire to characterize and analyze cooling in a broad class of TRIGA-type reactors under: (1) typical operating conditions, (2) anticipated, new operating regimes, and (3) postulated accident conditions. It has also provided experimental verification of analytical tools used in design analysis. The paper includes descriptions of the UNM thermal-hydraulics test facility and the experimental test sections. During the first two years experiments were conducted using single, electrically heated rod in water and air annuli. This configuration provides an observable and serviceable simulation of a fuel rod and its coolant channel.

  15. Computer-based programs on acquisition of reading skills in schoolchildren (review of contemporary foreign investigations

    Directory of Open Access Journals (Sweden)

    Prikhoda N.A.

    2015-03-01

    Full Text Available The article presents a description of 17 computer-based programs, which were used over the last 5 years (2008—2013 in 15 studies of computer-assisted reading instruction and intervention of schoolchildren. The article includes a description of specificity of various terms used in the above-mentioned studies and the contents of training sessions. The article also carries out a brief analysis of main characteristics of computer-based techniques — language of instruction, age and basic characteristics of students, duration and frequency of training sessions, dependent variables of education. Special attention is paid to efficiency of acquisition of different reading skills through computer-based programs in comparison to traditional school instruction.

  16. An Experimental Plasma Dynamo Program for Investigations of Fundamental Processes in Heliophysics

    CERN Document Server

    Brown, Benjamin; Nornberg, Mark; Zweibel, Ellen; Cattaneo, Fausto; Cowley, Steven

    2011-01-01

    Plasma experiments in laboratory settings offer unique opportunities to address fundamental aspects of the solar dynamo and magnetism in the solar atmosphere. We argue here that ground-based laboratory experiments have direct connections to NASA based missions and NSF programs, and that a small investment in laboratory heliophysics may have a high payoff. We advocate for broad involvement in community-scale plasma experiments.

  17. An Investigation of Participating to Continuous Medical Education Programs of Medical Staff at A State Hospital

    OpenAIRE

    Şeyda Ferah Tuygar

    2015-01-01

    Aim: This study was planned to determine the frequency, funding and effectiveness of continuous medical education programs which the medical staff at a state hospital attended. Method: This descriptive research was performed on 87 medical staff working at a state hospital (doctor, nurse, midwife, health officer, health technician, and pharmacist) who were accepted to participate in the study. The data were collected through face to face interviews with a questionnaire. Their answers assessed ...

  18. Final Report, Research Program to Investigate the Fundamental Chemistry of Technetium

    Energy Technology Data Exchange (ETDEWEB)

    Lukens Jr., Wayne W.; Fickes, Michael J.; Bucher, Jerome J.; Burns, Carol J.; Edelstein, Norman M.; Shuh, David K.

    2000-12-23

    The purpose is to increase the basic scientific understanding of technetium chemistry to better understand the behavior of technetium in chemical environments relevant to DOE. Two important areas in need of study are the behavior of technetium in highly alkaline solutions similar to high-level nuclear waste, and its behavior in different waste forms. This research program addressed these two needs. Two separate approaches were used in this program. The first focus was to understand the basic solution chemistry of technetium, which underlies its behavior in the highly alkaline environment of the nuclear waste tanks located at the Savannah River and Hanford Sites. The specific problems at these sites are related to the anomalous oxidation state of technetium (Schroeder 1995). Although, at high pH, technetium should exist in its highest oxidation state as TcO{sub 4}{sup {minus}}, soluble, lower-valent technetium species have been observed in certain wastes. The specific unknowns that this program sought to answer are the nature of lower valent technetium species that can be formed in highly alkaline solution and whether pertechnetate undergoes radiolytic reduction in highly alkaline solution when nitrate is present in excess. The second focus area is the behavior of technetium immobilized in various waste forms. The behavior of technetium in cement wastes was examined to gain information about its long-term stability. Specifically, this research examined the oxidation of reduced technetium species by components present in high-level waste that are incorporated into cement waste along with technetium.

  19. Animation & Neurocinematics*

    DEFF Research Database (Denmark)

    Carpe Pérez, Inmaculada Concepción

    2016-01-01

    machines that think”-(Damasio, A. Descartes error). Such feelings come from the interpretation of the emotions in our bodies. Emotions are our universal language, the motivation of living, the key to what makes a movie successful and truly an art piece that you will remember because moves you. Animation......, indeed, can be considered a social/ emotional learning media, which goes beyond the limitations of live action movies. This is due to the diversity of techniques, and its visual plasticity that constructs the impossible. Animators are not real actors but more like the midwife who brings the anima...... into aliveness, which requires knowing how emotions work. Ed Hooks as an expert in training animators and actors, always remarks: “emotions tend to lead to action”. In this paper we want to argue that by producing animated films, as we watch them, cause a stronger effect, not only in our brains, but also in our...

  20. Animal performance

    OpenAIRE

    Abaye, A. O. (Azenegashe Ozzie); Rotz, Jonathan Daniel; Scaglia Alonso, Guillermo, 1963-; Fike, John Herschel; Smith, Ray Lee, 1962-

    2009-01-01

    Any forage crop that stretches the grazing season by providing additional feed in early spring, mid-summer, and late fall will provide the livestock producer with lower feed costs and boost animal performance.

  1. Groundwater animals

    OpenAIRE

    Maurice, Louise; Bloomfield, John; Robertson, Anne; Allen, Debbie

    2010-01-01

    Groundwater animals are adapted to live in environments with no light and limited nutrients, They can provide insights into fundamental questions of evolution, ecology and biodiversity. They also have an important role to play in informing the reconstruction of past changes in geomorphology and climate, and can be used for characterising aquifers. The BGS is undertaking a systematic survey of selected areas and lithologies in the UK where groundwater animals have not been inves...

  2. Development of the web-based site investigation flow diagram in repository development program

    International Nuclear Information System (INIS)

    In siting a repository for high level radioactive wastes (HLW), it is essential for consensus building intelligibly and visually present why and how the area is selected as a suitable site. However 'information asymmetry' exists especially between society and an implementation body because various types of investigation, analysis and assessment are implemented in site characterization on the basis of a wide variety of advanced science and technology. Communication between experts (e.g. surveyors and modelers) is also important for efficient and reliable site investigation/ characterization. The Web-based Site Investigation Flow Diagram (SIFD) has been developed as a tool for information sharing among stake holders and society-jointed decision making. To test applicability of the SIFD, virtual site characterization ('dry run') is performed using the existing site investigation data. It is concluded that the web-based SIFD enhance traceability and transparency of the site investigation/ characterization, and therefore it would be a powerful communication tool among experts for efficient and reliable site investigation/characterization and among stake holders for consensus building

  3. Investigating the Problems of English Speaking of the Students of Islamic Boarding School Program at STAIN Samarinda

    OpenAIRE

    Sitti Hadijah

    2014-01-01

    This study investigated the students’ ability, the problems and their reasons why they faced problems on English speaking. The triangulation of mixed methods was used in this study. The quantitative data gathered from the speaking test result by involving 130 students of Islamic Boarding School Program and the qualitative data gathered from the questionnaire and interview results from the selected students who meet the criteria. The findings showed that the students’ ability was categorized l...

  4. Functional operation of a program package for investigating destructive processes in materials caused by electron pulse streams

    Energy Technology Data Exchange (ETDEWEB)

    Protsenko, S.S. [Kiev State Univ. (Russian Federation)

    1994-06-01

    We provide a mathematical formulation of problems solved by a package of programs for investigating destructive processes in materials caused by pulse streams of electrons. On the basis of a structural analysis we determine five groups of functional modules; we describe their purpose, the composition of the input/output data, and the sequence of operations at various stages of the solution of a problem.

  5. Inadvertently programmed bits in Samsung 128 Mbit flash devices: a flaky investigation

    Science.gov (United States)

    Swift, G.

    2002-01-01

    JPL's X2000 avionics design pioneers new territory by specifying a non-volatile memory (NVM) board based on flash memories. The Samsung 128Mb device chosen was found to demonstrate bit errors (mostly program disturbs) and block-erase failures that increase with cycling. Low temperature, certain pseudo- random patterns, and, probably, higher bias increase the observable bit errors. An experiment was conducted to determine the wearout dependence of the bit errors to 100k cycles at cold temperature using flight-lot devices (some pre-irradiated). The results show an exponential growth rate, a wide part-to-part variation, and some annealing behavior.

  6. Animal ethics dilemma

    DEFF Research Database (Denmark)

    Dich, Trine; Hansen, Tina; Algers, Anne;

    2006-01-01

    ) the blind hens; (2) ANDi the genetically modified monkey; (3) euthanasia of a healthy dog; (4) animal slaughter; and (5) rehabilitation of seals. Special consideration has been given to enhancing the pedagogic value of the program. Students can control their learning by selecting a variety of ways...

  7. 9 CFR 54.3 - Animals eligible for indemnity payments.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Animals eligible for indemnity payments. 54.3 Section 54.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... SCRAPIE Scrapie Indemnification Program § 54.3 Animals eligible for indemnity payments. (a) Indemnity...

  8. 9 CFR 54.7 - Procedures for destruction of animals.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Procedures for destruction of animals. 54.7 Section 54.7 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... SCRAPIE Scrapie Indemnification Program § 54.7 Procedures for destruction of animals. (a)...

  9. 9 CFR 55.6 - Mortgage against animals.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Mortgage against animals. 55.6 Section 55.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... DISEASE Chronic Wasting Disease Indemnification Program § 55.6 Mortgage against animals. When cervids...

  10. PCDD/PCDF and dioxin-like PCBs in animal fat samples from Switzerland. A monitoring program for revising Swiss food limits

    Energy Technology Data Exchange (ETDEWEB)

    Rottler, H. [Eurofins Oekometric, Bayreuth (Germany); Wuethrich, C.; Kuchen, A. [Swiss Federal Office of Public Health, Liebefeld (Switzerland)

    2004-09-15

    The European Commission (EC) stipulated maximum levels for dioxins in food in 2001 as an outcome result of their strategy to reduce dioxin and PCB levels. At that time the data base for dioxin-like PCBs was regarded as insufficient to include maximum levels for PCBs. Consequently, a study was initiated by the EC on a European-wide scale to collect information on dioxin-like PCBs in feed and food. The decision on European limits for dioxin-like PCBs is announced for end of 2004. As Switzerland is not a member of the European Union, European Commission limits are not valid per se and must be reassessed. As laid down in the Swiss Food Law it is the task of the Swiss Federal Office of Public Health (SFOPH) to collect the basic information necessary for initiating appropriate measures to protect consumers from foodstuff that could adversely affect their health. In this context information about total dioxin intake of the Swiss population is necessary. In view of the upcoming revision of the Swiss Ordinance on Foreign and Toxic Components in Foodstuffs (FIV) which should integrate limits for dioxins in food, it is now important to know whether the maximum contaminant limit for dioxins as fixed by the European Commission is also appropriate for Swiss consumer protection purposes. To answer this question and to fill existing data gaps in view of a more accurate calculation of the total dioxin intake of the Swiss population, an additional dioxin monitoring program started end of 2003 especially focusing on animal fat. Dioxin-like PCBs were included to complete the Swiss data base and to assess the Swiss intake situation for these compounds just in time before the corresponding European activities on dioxinlike PCBs.

  11. SIM: a one-dimensional two-fluid computer program to investigate the numerical solution scheme used in the SIMMER program

    International Nuclear Information System (INIS)

    SIMMER is widely used to model post fuel pin failure events of a Fast Reactor Accident. To investigate the numerical solution scheme used to solve the large number of differential equations, a much simplified version SIM has been produced. The equation system, finite difference representation and solution scheme are described for a single component (material) two fluid system with the liquid phase assumed to be incompressible and the gas phase an ideal gas. Results are in good agreement with theoretical values. The equation set is extended to include the full energy conservation equations of the two fluids, extending the range of the program. (UK)

  12. Investigation of the effect of selected aerobic programs on improving vocational relationships

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Iravani

    2011-10-01

    Full Text Available The new millennium has commenced with an increase awareness of precious value of human resources. Many large firms have increased to use new human resources mobilization policies and the importance of human potential in business has developed, dramatically. There different methods to help human resources increase their potentials such as providing recreational centers, athletic facilities, etc. In this paper, we study the impact of providing exercise facilities on improving the efficiency of employees in management level in the biggest steel producers in Iran called Mobarakeh Steel Complex. In this company, there were about 85 middle level managers and supervisors and the proposed study selects 30 people, randomly and divides them into two equal groups. In the first stage of the study, questionnaire of vocational relation are distributed among the participants of our experiment and we measure some important factors, which could improve vocational relationships. Next, the experimental groups are invited to take part in some selective aerobic programs for 8 weeks and 3 sessions per week and 1 hour and 15 minutes per session, regularly. Finally, we repeat the same experiments after the aerobic programs end and compare the results with the first one. The preliminary results indicate that there is a meaningful difference between the healthcares of these two groups.

  13. Subseabed disposal program annual report, January-December 1978. Volume II. Principal investigator progress reports

    International Nuclear Information System (INIS)

    The topics covered in this report include: geologic siting considerations for the disposal of radioactive wastes into submarine geologic formations; geologic assessment of the MPG-1 regions Central North Pacific; site mapping; geotechnical aspects of subsurface seabed disposal; heat transfer, thermal and fluid physics in the deep ocean sediments; mechanical response predictive capability; sediment-seawater interaction at 3000C, 500 bars; stability of actinides in chloride media; cannister corrosion studies; nuclide sorption and migration; development of apparatus and measurement of thermal conductivity of seabed illite and smectite at temperatures to 5000C at simulated depths to 15,000 ft (9000 psi); in-situ heat transfer experiments; preliminary seabed disposal transport modeling studies; radionuclide migration studies; radionuclide distributions in deep ocean cores; benthic biological studies; deep sea microbial studies; activity rates of abyssal communities; Deep-towed RUM III (Sandia Seabed working platform): a third-generation remote underwater manipulator; long coring facility program; transportation; legal, political, and institutional implications of the Seabed Program for radioactive waste disposal

  14. An investigation of integral facility scaling and data relation methods (Integral System Test Program)

    International Nuclear Information System (INIS)

    The Integral Systems Test (IST) Program was initiated in 1982 by government and industry to provide information needed to help resolve issues raised by the accident at the Three Mile Island nuclear power station. Three different integral test facilities, each scaled to a Babcock and Wilcox (B and W) design nuclear steam supply system, will ultimately contribute data to meet the objectives of the program. Each of the facilities was designed using different scaling methodologies, and each has different operating capabilities, such as maximum operating pressure and core power. The overall scaling of each facility is examined in this report, and local scaling is analyzed to demonstrate potential similarities and dissimilarities in facility response relative to expected plant responses. The scaling relationships are used to show how local thermal-hydraulic phenomena in each facility can be compared to each other or to expected plant behavior. The concept of an equilibrium plot is used to show how the global response of each facility can be related for a specific small break loss-of-coolant transient. Potential complications that may arise as a consequence of the facility scaling or facility limitations are enumerated. The potential use of dimensionless groupings for relating and specifying experiments is discussed. Finally, some specific experiments and conditions are proposed for the purpose of simplifying interfacility comparison of test results

  15. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1995

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, M.J.; Brooks, R.D.; Sassaman, K.E.; Crass, D.C. [and others

    1995-10-01

    The Savannah River Archaeological Research Program (SRARP) continued through FY95 with the United States Department of Energy to fulfill a threefold mission of cultural resource management, research, and public education at the Savannah River Site. Over 2,300 acres of land on the SRS came under cultural resources review in FY95. This activity entailed 30 field surveys, resulting in the recording of 86 new sites. Twenty-two existing sites within survey tract boundaries were revisited to update site file records. Research conducted by SRARP was reported in 11 papers and monographs published during FY95. SRARP staff also presented research results in 18 papers at professional meetings. Field research included several testing programs, excavations, and remote sensing at area sites, as well as data collection abroad. Seven grants were acquired by SRARP staff to support off-site research. In the area of heritage education, the SRARP expanded its activities in FY95 with a full schedule of classroom education, public outreach, and on-site tours. Volunteer excavations at the Tinker Creek site were continued with the Augusta Archaeological Society and other avocational groups, and other off-site excavations provided a variety of opportunities for field experience. Some 80 presentations, displays and tours were provided for schools, historical societies, civic groups, and environmental and historical awareness day celebrations. Additionally, SRARP staff taught four anthropology courses at area colleges.

  16. Investigations of multiresistance to antibiotics and chemotherapeutics and extended spectrum beta: Lactamase effect (ESBL test) in strains E.coli and salmonella originating from domestic animals

    OpenAIRE

    Mišić Dušan; Stošić Zorica; Kiškarolj Ferenc; Adamov Vladica; Ašanin Ružica

    2006-01-01

    The presence of multiresistance to the effects of antibiotics and chemotherapeutics and extended spectrum beta-lactamase were examined in 45 strains of E. coli and 35 strains of Salmonella. The strains of E. coli originated from several species of domestic animals: dogs, cats, poultry, and cattle, and 30 strains of Salmonella originated from poultry, 4 strains from cattle, and 1 strain from swine. The presence of the following serovarieties was established using serological examinations: Salm...

  17. Investigating the Language Learning Strategies of Students in the Foundation Program of United Arab Emirates University

    Science.gov (United States)

    Ismail, Sadiq Abdulwahed Ahmed; Al Khatib, Ahmad Z.

    2013-01-01

    Recently, language learning strategies have gained a lot of importance in different parts of the world, including the United Arab Emirates (UAE). Successful foreign or second language learning attempts are viewed in the light of using appropriate and effective language learning strategies. This study investigated the patterns of language learning…

  18. Learning Mathematics by Designing, Programming, and Investigating with Interactive, Dynamic Computer-Based Objects

    Science.gov (United States)

    Marshall, Neil; Buteau, Chantal

    2014-01-01

    As part of their undergraduate mathematics curriculum, students at Brock University learn to create and use computer-based tools with dynamic, visual interfaces, called Exploratory Objects, developed for the purpose of conducting pure or applied mathematical investigations. A student's Development Process Model of creating and using an Exploratory…

  19. Evaluation of an Implementation Model : A National Investigation of VA Residential Programs

    NARCIS (Netherlands)

    Cook, Joan M.; Dinnen, Stephanie; Coyne, James C.; Thompson, Richard; Simiola, Vanessa; Ruzek, Josef; Schnurr, Paula P.

    2015-01-01

    This national investigation utilizes qualitative data to evaluate an implementation model regarding factors influencing provider use of two evidence-based treatments for posttraumatic stress disorder (PTSD). Semi-structured qualitative interviews with 198 mental health providers from 38 Department o

  20. 脑胶质瘤动物模型的研究及应用进展%Animal models of human glioma: the progress of application and investigation

    Institute of Scientific and Technical Information of China (English)

    朱惠芳; 张远旭; 赵旭东

    2012-01-01

    脑胶质瘤约占中枢神经肿瘤的一半,临床治疗效果差.尤其是胶质母细胞瘤,其恶性程度极高,预后性差,是威胁人类健康的主要恶性肿瘤之一,因此,选择一种有效的动物模型是研究脑胶质瘤发病机制及其治疗方法的关键.随着分子生物学、遗传学的发展,尤其是转基因小鼠,以及其他越来越多模式生物的出现,目前已建立了多种脑胶质瘤动物模型.该文将对目前所建立的各种脑胶质瘤动物模型予以综述.%The glioma accounts for half of the central nervous tumors, among which the glioblastoma multifonne (GBM) is one of the most aggressive and lethal brain tumors. The difficulties in glioma therapy indicate the need of appropriate animal models for preclinical studies. Benefiting from the development of molecular biology, genetics, and transgenic technology, variable animal models of glioma have been established. These animal models of human glioma are reviewed in this paper.

  1. Investigating the impact of a preservice program on beliefs about science teaching and learning

    Science.gov (United States)

    Soldat, Christopher Scott

    There has been much attention about improving the skills and abilities of students in Science. One critical factor is the quality of teacher education programs for preparing science teachers. There has been little research and much debate about what constitutes an effective science teacher education program. Teacher beliefs are thought to be important factors which influence how science teachers teach. This is a three year longitudinal study which explores changes in twelve teachers using a mixed method design. Semi-structured interviews were used to explore the beliefs about teaching, learning, and the Nature of Science. Four cohorts of teachers represented the different critical stages of the teaching continuum. Two cohorts of teachers represented entry and exit stages of preservice education. The other two cohorts represented teachers who taught less than four years and more than four years in the classroom. Classroom observations and self-reported surveys were gathered. The major outcomes of this research include: (1) Teacher beliefs about teaching and learning shift towards being more student-centered during their preservice education; (2) Despite previous reports that most graduates revert to teacher-centered beliefs in the first years of teaching, the beliefs of Iowa preservice teacher beliefs, remained similar to their previous student-centered beliefs; (3) Teacher beliefs about the Nature of Science, which were initially represented as a socially constructed entity, became less frequent as 2 teachers progress through the teaching continuum from preservice to inservice teachers; (4) Student-centered beliefs about teaching and learning, derived from teacher interviews, are correlated with classroom observations and self-reported surveys of instructional strategies. The findings from this study shed light on understandings concerning the evolution of teacher beliefs. Factors effecting teacher beliefs include college preparatory education programs, school

  2. Investigation and development of computer programs for the analysis of texture and anisotropy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yong Che; Lee, Chang Hee; Seong, Baek Seok

    1998-12-01

    In anticipation of texture measurements using the four circle diffractometer at HANARO reactor we assessed the standard texture analysis packages, popLA (Preferred orientation package - Los Alamos) and BEARTEX (Berkeley Texture Package). Both are PC-oriented packages of utility programs that perform comprehensive task incorporating data acquisition, corrections and presentation of results in graphics display as well as orientation distribution (OD) analysis. In the main OD analysis the former follows both the conventional harmonic method as well as the more accurate WIMV method, while the latter solely rely on WIMV algorithm. In spite of involved calculations both packages are so fast that most OD analysis can be done in less than a few minutes. We think all the effective features of the packages qualify them to be used as backbone of a software system for texture experiments at the HANARO reactor.

  3. Partition and poliomyelitis: an investigation of the polio disparity affecting Muslims during India's eradication program.

    Directory of Open Access Journals (Sweden)

    Rashid S Hussain

    Full Text Available Significant disparities in the incidence of polio existed during its eradication campaign in India. In 2006, Muslims, who comprise 16% of the population in affected states, comprised 70% of paralytic polio cases. This disparity was initially blamed on the Muslims and a rumor that the vaccination program was a plot to sterilize their children. Using the framework of structural violence, this paper describes how the socio-political and historical context of Muslim populations in India shaped the polio disparity.A qualitative study utilizing methods of rapid ethnography was conducted from May-August 2009 in Aligarh, Uttar Pradesh, India. Field methods included participant observation of vaccination teams, historical document research, and 107 interviews with both Global Polio Eradication Initiative (GPEI stakeholders and families with vaccine-eligible children. Almost all respondents agreed that Aligarh was a highly segregated city, mostly due to riots after Partition and during the 1990s. Since the formation of segregated neighborhoods, most respondents described that "Muslim areas" had been underdeveloped compared to "Hindu areas," facilitating the physical transmission of poliovirus. Distrust of the government and resistance to vaccination were linked to this disparate development and fears of sterilization influenced by the "Family Planning Program" from 1976-1977.Ethnic violence and social marginalization since the Partition and during the rise of Hindu nationalism led to distrust of the government, the formation of segregated slums, and has made Muslims victims of structural violence. This led to the creation of disease-spreading physical environments, lowered vaccine efficacy, and disproportionately higher levels of resistance to vaccination. The causes of the polio disparity found in this study elucidate the nature of possible other health disparities affecting minorities in India.This study is limited by the manual coding of the

  4. Partition and Poliomyelitis: An Investigation of the Polio Disparity Affecting Muslims during India's Eradication Program

    Science.gov (United States)

    Hussain, Rashid S.; McGarvey, Stephen T.; Fruzzetti, Lina M.

    2015-01-01

    Background Significant disparities in the incidence of polio existed during its eradication campaign in India. In 2006, Muslims, who comprise 16% of the population in affected states, comprised 70% of paralytic polio cases. This disparity was initially blamed on the Muslims and a rumor that the vaccination program was a plot to sterilize their children. Using the framework of structural violence, this paper describes how the socio-political and historical context of Muslim populations in India shaped the polio disparity. Methods and Findings A qualitative study utilizing methods of rapid ethnography was conducted from May-August 2009 in Aligarh, Uttar Pradesh, India. Field methods included participant observation of vaccination teams, historical document research, and 107 interviews with both Global Polio Eradication Initiative (GPEI) stakeholders and families with vaccine-eligible children. Almost all respondents agreed that Aligarh was a highly segregated city, mostly due to riots after Partition and during the 1990s. Since the formation of segregated neighborhoods, most respondents described that "Muslim areas" had been underdeveloped compared to "Hindu areas," facilitating the physical transmission of poliovirus. Distrust of the government and resistance to vaccination were linked to this disparate development and fears of sterilization influenced by the "Family Planning Program" from 1976-1977. Conclusions Ethnic violence and social marginalization since the Partition and during the rise of Hindu nationalism led to distrust of the government, the formation of segregated slums, and has made Muslims victims of structural violence. This led to the creation of disease-spreading physical environments, lowered vaccine efficacy, and disproportionately higher levels of resistance to vaccination. The causes of the polio disparity found in this study elucidate the nature of possible other health disparities affecting minorities in India. Limitations This study is

  5. The effects of musical training on movement pre-programming and re-programming abilities: an event-related potential investigation.

    Science.gov (United States)

    Anatürk, Melis; Jentzsch, Ines

    2015-03-01

    Two response precuing experiments were conducted to investigate effects of musical skill level on the ability to pre- and re-programme simple movements. Participants successfully used advance information to prepare forthcoming responses and showed response slowing when precue information was invalid rather than valid. This slowing was, however, only observed for partially invalid but not fully invalid precues. Musicians were generally faster than non-musicians, but no group differences in the efficiency of movement pre-programming or re-programming were observed. Interestingly, only musicians exhibited a significant foreperiod lateralized readiness potential (LRP) when response hand was pre-specified or full advance information was provided. These LRP findings suggest increased effector-specific motor preparation in musicians than non-musicians. However, here the levels of effector-specific preparation did not predict preparatory advantages observed in behaviour. In sum, combining the response precuing and ERP paradigms serves a valuable tool to examine influences of musical training on movement pre- or re-programming processes. PMID:25666744

  6. An Investigation of Intestinal Parasitic Infection in Ornamental Carnivorous Animals Raised in Scatters and in Sites%半散养和圈养肉食目动物肠道寄生虫感染情况调查

    Institute of Scientific and Technical Information of China (English)

    金兰梅; 周加武; 高小梅; 徐美娜; 蔡志慧; 夏国强; 周玲玲; 沈素娟

    2012-01-01

    The paper investigates parasitic infection in ornamental carnivorous animals raised in scatters and in sites.116 fecal samples representing 4 families of animals such as the tiger,lion,bear,and wolf,are examined by flotation and sedimentation.It shows that the total infection rate of helminth is 71.55%.The infection rate of animals raised in scatter is 74%,while that of captive animals is 56.39%.The average infectivity of nematode in animals raised in scatter is 10 158,among which the highest EPG is 23 400.The average infectivity of fluke nematode in animals raised in scatter is 6 008,among which the highest EPG is 33 600.The average infectivity of coccidiosis in animals raised in scatter is 142.The average infectivity of nematode in captive animals is 350,among which the highest EPG is 600.The average infectivity of coccidiosis in captive animals is 120,among which the highest EPG is 600.The average infectivity of flupe nematode in captive animals is 0.%为了解动物园半散养和圈养肉食目动物寄生虫的感染状况,采用饱和盐水漂浮法和水洗沉淀法对虎、狮、熊、狼等116头肉食动物粪便进行了寄生虫检查。结果显示:寄生虫总感染率为71.55%,半散养的肉食目动物寄生虫的感染率为74%(74/100),圈养的感染率为56.3%(9/16)。半散养的线虫平均感染强度(EPG)为10158,其中EPG值最高的达23 400;吸虫平均感染强度(EPG)为6 008,其中EPG值最高的达33 600;球虫平均感染强度(EPG)为142。圈养的线虫平均感染强度(EPG)为350,其中EPG值最高的达600;球虫平均感染强度(EPG)为120,其中EPG值最高的达600;吸虫的平均感染强度(EPG)为0。

  7. Investigation for integration of the German Public Health Service in catastrophe and disaster prevention programs in Germany

    International Nuclear Information System (INIS)

    This research project aimed at investigating the integration of the GPHS into the plans for civil defence and protection as well as catastrophe prevention of the Federal Republic of Germany. Following a comprehensive analysis of the current situation, potential proposals for an improved integrative approach will be presented. In view of the lack of topics relevant for medical care in disaster medicine in educational curricula and training programs for medical students and postgraduate board programs for public health physicians, a working group of the Civil Protection Board of the German Federal Ministry of the Interior already complained in their 'Report on execution of legal rules for protection and rescue of human life as well as restitution of public health after disaster' in 1999, that the integration of the GPHS into catastrophe and disaster prevention programs has insufficiently been solved. On a point-by-point approach, our project analysed the following issues: - Legislative acts for integration of the German Public Health Service into medical care in catastrophes and disasters to protect the civilian population of Germany and their implementation and execution. - Administrative rules and directives on state and district levels that show relationship to integration of the German Public Health Service into preparedness programs for catastrophe prevention and management and their implementation and execution. - Education and postgraduate training options for physicians and non-physician employees of the German Public health Service to prepare for medical care in catastrophes and disasters. - State of knowledge and experience of the German Public Health Service personnel in emergency and disaster medicine. - Evaluation of the German administrative catastrophe prevention authorities with regard to their integration of the German Public Health Service into preparedness programs for catastrophe prevention and management. - Development of a concept to remedy the

  8. Geophysical investigation program for Northern Switzerland: Aeromagnetic and groundmagnetic measurements 81

    International Nuclear Information System (INIS)

    In the framework of the geophysical investigations of NAGRA in Northern Switzerland the Swiss Geophysical Commission has surveyed a total of 6250 km of aeromagnetic lines at two different flight levels. Furthermore, a ground-magnetic pilot programme comprising 1480 stations was carried out in the Hornussen area. The aeromagnetic data are presented on a series of maps. They show no anomalies that allow a determination of the depth to the crystalline basement and of the Permo-carboniferous trough embedded therein. A modelling study has shown that this phenomena can be explained by the small susceptibility contrasts between sediments and crystalline rocks as determined on core samples. The ground-magnetic investigations do not allow an interpretation as all mapped anomalies had to be attributed to man-made sources. (author)

  9. Standing for Animals

    OpenAIRE

    Sunstein, Cass Robert

    1999-01-01

    From the legal point of view, there is nothing at all new or unfamiliar in the idea of "animal rights;" on the contrary, it is entirely clear that animals have legal rights. Indeed, the rise of legal rights for animals has been one of the most distinctive features of the last thirty years of federal statutory law. An investigation of the question of standing helps show that the real issues involve problems of enforcement and scope. Human beings often do and should have standing to protect ani...

  10. Investigation of the organic matter in inactive nuclear tank liquids. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Schenley, R.L.; Griest, W.H.

    1990-08-01

    Environmental Protection Agency (EPA) methodology for regulatory organics fails to account for the organic matter that is suggested by total organic carbon (TOC) analysis in the Oak Ridge National Laboratory (ORNL) inactive nuclear waste-tank liquids and sludges. Identification and measurement of the total organics are needed to select appropriate waste treatment technologies. An initial investigation was made of the nature of the organics in several waste-tank liquids. This report details the analysis of ORNL wastes.

  11. Experimental Animal Welfare

    OpenAIRE

    Yusuf Ergun

    2011-01-01

    It is an obvious obligation for investigators to consume millions of experimental animals every year to obtain scientific data. Because most of these experiments involve painful and distressing procedures, to obey the so-called 3Rs, reduction, refinement and replacement, is a prerequisite for those who would apply to ethics committees for a given research proposal. Of the 3Rs, refinement could be defined as “decrease in the incidence of severity of inhumane procedures applied to those animals...

  12. Animal Models of Fibromyalgia

    OpenAIRE

    Nagakura, Yukinori; Ito, Hiroyuki; Shimizu, Yasuaki

    2012-01-01

    Animal models of disease states are valuable tools for developing new treatments and investigating underlying mechanisms. They should mimic the symptoms and pathology of the disease and importantly be predictive of effective treatments. Fibromyalgia is characterized by chronic widespread pain with associated co-morbid symptoms that include fatigue, depression, anxiety and sleep dysfunction. In this review, we present different animal models that mimic the signs and symptoms of fibromyalgia. T...

  13. Animated symbols

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2008-01-01

    This paper is based on data about animation film production by 18-year-old students in a Danish upper secondary school. The optic is the on-going potential for learning and development of reflection. The purpose is to clarify what might support young people's reflection on media. I propose...... an analytic working model called Animated Symbols concerning critical reflection in a dialogic learning process. The model shows dialogue as interactions that involve two types of transformation: inner ‘learning processes' and outer signs and symbols. The classroom-based research study is part of a Ph...

  14. Biotecnologia animal

    OpenAIRE

    Luiz Lehmann Coutinho; Millor Fernandes do Rosário; Erika Cristina Jorge

    2010-01-01

    A biotecnologia animal tem fornecido novas ferramentas para os programas de melhoramento e, dessa forma, contribuído para melhorar a eficiência da produção dos produtos de origem animal. No entanto, os avanços têm sido mais lentos do que antecipados, especialmente em razão da dificuldade na identificação dos genes responsáveis pelas características fenotípicas de interesse zootécnico. Três estratégias principais têm sido utilizadas para identificar esses genes - mapeamento de QTL, genes candi...

  15. An Exploratory Investigation of the Assessment Practices of Selected Association to Advance Collegiate Schools of Business--Accredited Business Programs and Linkages with General Education Outcomes

    Science.gov (United States)

    Vitullo, Elizabeth; Jones, Elizabeth A.

    2010-01-01

    This research study investigated the assessment practices of five different undergraduate business programs. It examines the learning outcomes required for the business programs and their linkages with general education outcomes. Specific assessment methods, the results from assessments, and how business program faculty use assessment findings to…

  16. INVESTIGATION OF STUDENT’S PERSONALITY ON PAIR PROGRAMMING TO ENHANCE THE LEARNING ACTIVITY IN THE ACADEMIA

    Directory of Open Access Journals (Sweden)

    V. Venkatesan

    2014-01-01

    Full Text Available Agile Software development is now a global phenomenon and is rapidly becoming organizations’ most preferred IT process. Extreme Programming (XP is one of the Agile Methods and Collaborative Pair Programming (CPP is one of the very important practices of eXtreme Programming. Agile focuses team work which is very important in the field of software development. The software industry has practiced CPP, where two programmers working side by side on one computer on the same problem with great success. Similar experiments have been conducted in academia and pair programming has been shown to be beneficial for both students and teaching staff in university courses. In this study, we conducted some set of experiments about the “human” aspect of the CPP; in particular the effects that personality attributes may have on pair programmer’s effectiveness as a pedagogical tool. A formal experiment has been conducted during 2012-13 odd semester at the PSG College of Technology, India to investigate the influence of personality differences among paired students using the five-factor model as a personality measurement framework. The aim of this research is to improve the implementation of CPP as a pedagogical tool to the academic setup through understanding the impact of the variation in the personality profile of paired students towards their academic performance.

  17. An 8-week reactive balance training program in older healthy adults:A preliminary investigation

    Institute of Scientific and Technical Information of China (English)

    Max R. Paquette; Yuhua Li; Joseph Hoekstra; Joshua Bravo

    2015-01-01

    Background:This preliminary study examined the effects of an 8-week supervised reactive balance training program on reaction time (RT) and foot speed, static balance and balance confidence in healthy older adults compared to an exercise control group. Methods:Twenty-five older adults were randomly assigned to a reactive balance training group (QuickBoard;n=12;71.0 ± 8.6 years) or a stationary cycling group (control; n = 13; 70.2 ± 6.0 years). Both groups were tested for foot RT foot speed, static balance, and balance confidence at baseline, 4-week, 8-week, and 4-week follow-up. Results: Results indicated significant improvements in QuickBoard foot RT and speed in both groups with greater improvements in the QuickBoard group. However, no group difference was found in static balance performance. Conclusion: Although the improvements in RT and foot speed may be beneficial for fall and trip prevention, the implications of the current findings for trip avoidance and performance of daily tasks are unclear.

  18. Ontario Securities Commission has authority to investigate viatical settlement purchase program.

    Science.gov (United States)

    Cruess, Gord

    2004-04-01

    On 27 October 2003, the Ontario Superior Court of Justice held that the Ontario Securities Commission (the Commission) has the authority to compel testimony and the production of written documents from parties that are not registered under the Ontario Securities Act (OSA). The finding in Universal Settlements International, Inc v Ontario (Securities Commission) is important because it affirms the authority of the Commission to investigate businesses that might be engaging in the sale of illegal viatical settlements, an unregulated industry with potential negative impacts for people living with HIV/AIDS. PMID:15216839

  19. Animal house

    OpenAIRE

    Turka, Laurence A.

    2008-01-01

    While the JCI was originally conceived as a journal that would integrate various scientific approaches to the examination of human physiology and pathophysiology, we now find many of its pages filled with animal models of human disease. Is this a good thing?

  20. Animated war

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2012-01-01

    production: Gzim Rewind (Sweden, 2011) by Knutte Wester, and In-World War (USA, expected 2011) by DJ Bad Vegan. These films have themes of war and include film scenes that are ‘machinima’ (real-time animation made in 3D graphic environments) within live action film scenes. Machinima harnesses the...

  1. Animated Symbols

    DEFF Research Database (Denmark)

    Frolunde, Lisbeth

    ' processer af fem udvalgte elever er gennemgået i forhold til tre opdelinger: filmskabere, filmskabelse processen og film. Den teoretiske tilgang er pragmatisme, social semiotik og diskursanalyse. Modellen "Animating Symbols" er udviklet og diskuteret som forsøg på at forstå reflektion og design som en slags...

  2. Transgenic Animals.

    Science.gov (United States)

    Jaenisch, Rudolf

    1988-01-01

    Describes three methods and their advantages and disadvantages for introducing genes into animals. Discusses the predictability and tissue-specificity of the injected genes. Outlines the applications of transgenic technology for studying gene expression, the early stages of mammalian development, mutations, and the molecular nature of chromosomes.…

  3. Discobiol program : investigation of dispersant use in coastal and estuarine waters

    Energy Technology Data Exchange (ETDEWEB)

    Merlin, F.X.; Le Floch, S.; Dussauze, M. [Cedre, Brest Cedex (France); Theron, M. [Brest Univ., European University of Britanny, Rennes (France); Quentel, C. [AFSSA, French Food Safety Agency, Paris (France); Thomas, H. [LIENS, CNRS-Univ. of La Rochelle, La Rochelle Cedex (France)

    2009-07-01

    This paper reported on the Discobiol work program designed to acquire comparable information on the impact of mechanically and chemically dispersed oil on different habitats and resources, particularly in estuaries or close to bays. The study involved 3 phases for the analysis of lethal and sub-lethal effects in pelagic and benthic communities, notably organisms in the water column, mudflats and salt marshes. The ultimate objective was to use the information to make recommendations regarding the use of dispersants in these 3 areas. Dispersants are known to be effective for offshore oil spill response when dilution conditions are high and dispersed oil concentrations decrease rapidly below levels that could harm the environment. However, dilution can be restricted in coastal areas, thus limiting the use of dispersant. All the tests conducted in this study were conducted using brut Arabian light oil that was pre-evaporated to simulate realistic conditions. The study examined whether the presence of oil leads to different effects than the control and whether the chemically dispersed oil gave different effects than the mechanical dispersion. The comparison with chemical dispersion in clear sea water examined whether the presence of suspended materials change the effect of the chemical dispersion. Results for the different phases of the project were presented. The preliminary results tend to open the use of chemical dispersion of oil slicks in coastal areas. The mixture of dispersant plus oil seems to be less detrimental than oil alone, particularly for turbot. The final conclusion regarding chemical dispersion of oil slicks in coastal areas will have to be formulated at the end of the project because coastal ecosystems depend on biotic and abiotic factors. The final phase will take place in a realistic environment in a salt marsh ecosystem at La Rochelle, France. 6 refs., 6 tabs., 6 figs.

  4. Investigation and subsurface remediation program for acetone in gulf coast sediments

    International Nuclear Information System (INIS)

    Failure of a subsurface pipeline and a rail car loading header caused a release of acetone to the shallow subsurface sediments at a Texas Gulf Coast chemical plant. A channel sand deposit was mapped beneath the release location consisting of fine grained sand below 10 feet of clay. The channel geometry and acetone distribution in the subsurface were delineated by a series of boreholes for the installation of monitor wells. The channel sand is approximately 30 feet thick and 150 feet wide. Aquifer test analyses show the transmissivity of the sand deposit to be about 400 ft2 /day. The acetone concentration in the ground water exceeded 100,000 mg/L with the greatest concentrations stratified at the top of the saturated zone. A ground water remediation program has been underway for more than three years. It was found that a single well, screened through the entire thickness of the sand deposit and pumped at eight gpm could effectively capture the contaminant plume, however the average concentration of acetone in the discharge fluid was only 800 mg/L. Alternate pumping schemes have been tried to evolve a more efficient recovery operation. Additionally, a top filling pneumatic pump was installed to take advantage of the higher concentrations of acetone found at the top of the saturated zone. Attempts were made to determine if a particular pumping scheme was more efficient for the ground water remediation. Both intermittent and continuous pumping were tried. Samples were collected to determine the concentrations of the discharge water and the total mass of recovered acetone. It was found that intermittent pumping of the recovery wells did not recover as much acetone as continuous pumping

  5. Nye County Nuclear Waste Repository Project Office independent scientific investigations program annual report, May 1997 - April 1998

    International Nuclear Information System (INIS)

    This annual summary report, prepared by the Nye County Nuclear Waste Repository Project Office (NWRPO), summarizes the activities that were performed during the period from May 1, 1997 to April 30, 1998. These activities were conducted in support of the Independent Scientific Investigation Program (ISIP) of Nye County at the Yucca Mountain Site (YMS). The Nye County NWRPO is responsible for protecting the health and safety of the Nye County residents. NWRPO's on-site representative is responsible for designing and implementing the Independent Scientific Investigation Program (ISIP). Major objectives of the ISIP include: Investigating key issues related to conceptual design and performance of the repository that can have major impact on human health, safety, and the environment; identifying areas not being addressed adequately by the Department of Energy (DOE). Nye County has identified several key scientific issues of concern that may affect repository design and performance which were not being adequately addressed by DOE. Nye County has been conducting its own independent study to evaluate the significance of these issues. This report summarizes the results of monitoring from two boreholes and the Exploratory Studies Facility (ESF) tunnel that have been instrumented by Nye County since March and April of 1995. The preliminary data and interpretations presented in this report do not constitute and should not be considered as the official position of Nye County. The ISIP presently includes borehole and tunnel instrumentation, monitoring, data analysis, and numerical modeling activities to address the concerns of Nye County

  6. Nye County Nuclear Waste Repository Project Office independent scientific investigations program annual report, May 1997--April 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    This annual summary report, prepared by the Nye County Nuclear Waste Repository Project Office (NWRPO), summarizes the activities that were performed during the period from May 1, 1997 to April 30, 1998. These activities were conducted in support of the Independent Scientific Investigation Program (ISIP) of Nye County at the Yucca Mountain Site (YMS). The Nye County NWRPO is responsible for protecting the health and safety of the Nye County residents. NWRPO`s on-site representative is responsible for designing and implementing the Independent Scientific Investigation Program (ISIP). Major objectives of the ISIP include: Investigating key issues related to conceptual design and performance of the repository that can have major impact on human health, safety, and the environment; identifying areas not being addressed adequately by the Department of Energy (DOE). Nye County has identified several key scientific issues of concern that may affect repository design and performance which were not being adequately addressed by DOE. Nye County has been conducting its own independent study to evaluate the significance of these issues. This report summarizes the results of monitoring from two boreholes and the Exploratory Studies Facility (ESF) tunnel that have been instrumented by Nye County since March and April of 1995. The preliminary data and interpretations presented in this report do not constitute and should not be considered as the official position of Nye County. The ISIP presently includes borehole and tunnel instrumentation, monitoring, data analysis, and numerical modeling activities to address the concerns of Nye County.

  7. Nye County nuclear waste repository project office independent scientific investigations program. Summary annual report, May 1996--April 1997

    International Nuclear Information System (INIS)

    This annual summary report, prepared by Multimedia Environmental Technology, Inc. (MET) on behalf of Nye County Nuclear Waste Project Office, summarizes the activities that were performed during the period from May 1, 1996 to April 30, 1997. These activities were conducted in support of the Independent Scientific Investigation Program (ISIP) of Nye County at the Yucca Mountain Site (YMS). The Nye County NWRPO is responsible for protecting the health and safety of the Nye County residents. NWRPO's on-site representative is responsible for designing and implementing the Independent Scientific Investigation Program (ISIP). Major objectives of the ISIP include: (1) Investigating key issues related to conceptual design and performance of the repository that can have major impact on human health, safety, and the environment. (2) Identifying areas not being addressed adequately by DOE Nye County has identified several key scientific issues of concern that may affect repository design and performance which were not being adequately addressed by DOE. Nye County has been conducting its own independent study to evaluate the significance of these issues

  8. Rapid Determination of Ractopamine Residues in Edible Animal Products by Enzyme-Linked Immunosorbent Assay: Development and Investigation of Matrix Effects

    Directory of Open Access Journals (Sweden)

    Yan Zhang

    2009-01-01

    Full Text Available To determine ractopamine residues in animal food products (chicken muscle, pettitoes, pig muscle, and pig liver, we established a rapid direct competitive enzyme-linked immunosorbent assay (ELISA using a polyclonal antibody generated from ractopamine-linker-BSA. The antibody showed high sensitivity and specificity in phosphate buffer, with an IC50 of 0.6 ng/mL, and the limit of detection was 0.04 ng/mL. The matrix effect of the samples was easily eliminated by one-step extraction with PBS, without any organic solution or clean-up procedure such as SPE or liquid-liquid extraction, making it a much more simple and rapid method than previously reported ones. The detection limit in blank samples was 0.2 μg/kg. To validate this new RAC (ractopamine hydrochloride ELISA, a RAC-free pig liver sample spiked at three different concentrations was prepared and analyzed by HPLC and ELISA. The results showed a good correlation between the data of ELISA and HPLC (R2>0.95, which proves that the established ELISA is accurate enough to quantify the residue of RAC in the animal derived foods.

  9. U.S. GEOLOGICAL SURVEY PROGRAMS AND INVESTIGATIONS RELATED TO SOIL AND WATER CONSERVATION

    Institute of Scientific and Technical Information of China (English)

    W.R.OSTERKAMP; J.R.GRAY

    2001-01-01

    The U.S. Geological Survey has a rich tradition of collecting hydrologic data, especially for fluxes of water and suspended sediment, that provide a foundation for studies of soil and water conservation.Applied and basic research has included investigations of the effects of land use on rangelands,croplands, and forests; hazards mapping; derivation of flood and drought frequency, and other statistics related to streamflow and reservoir storage; development and application of models of rainfall-runoff relations, chemical quality, and sediment movement; and studies of the interactive processes of overland and channel flow with vegetation. Networks of streamgaging stations and (or) sampling sites within numerous drainage basins are yielding information that extends databases and enhances the ability to use those data for interpretive studies.

  10. Radiative property investigation. [digital computer programs for determining bidirectional reflectance of spacecraft materials

    Science.gov (United States)

    Scott, R. L., Jr.

    1974-01-01

    A detailed formulation of radiative heat transfer problems involving the use of bidirectional reflectance is discussed. Except for very simple systems this formulation is very intricate. For this reason and the fact that bidirectional data are scarce, such a formulation is not in common use. However, with the development of the digital computer there have been numerical methods developed for detailed radiative investigations using the bidirectional reflectance. Since computations using bidirectional reflectance are coming into use for spacecraft radiative studies, it is necessary to have reflectance data on the materials involved. Materials that are frequently studied are coatings which are used in controlling the thermal environment of spacecrafts. This study is primarily concerned with the bidirectional reflectance of zinc oxide which is one constituent commonly used for coatings.

  11. Marine animal sighting and census data as part of the Outer Continental Shelf Environmental Assessment Program (OCSEAP) from 10 July 1978 to 29 August 1978 (NODC Accession 7900078)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Marine animal sighting and census data were collected from 10 July 1978 to 29 August 1978. Data were collected by the University of Alaska - Fairbanks; Institute of...

  12. Animal facilities

    International Nuclear Information System (INIS)

    The animal facilities in the Division are described. They consist of kennels, animal rooms, service areas, and technical areas (examining rooms, operating rooms, pathology labs, x-ray rooms, and 60Co exposure facilities). The computer support facility is also described. The advent of the Conversational Monitor System at Argonne has launched a new effort to set up conversational computing and graphics software for users. The existing LS-11 data acquisition systems have been further enhanced and expanded. The divisional radiation facilities include a number of gamma, neutron, and x-ray radiation sources with accompanying areas for related equipment. There are five 60Co irradiation facilities; a research reactor, Janus, is a source for fission-spectrum neutrons; two other neutron sources in the Chicago area are also available to the staff for cell biology studies. The electron microscope facilities are also described

  13. Animal Locomotion

    CERN Document Server

    Taylor, Graham K; Tropea, Cameron

    2010-01-01

    This book provides a wide-ranging snapshot of the state-of-the-art in experimental research on the physics of swimming and flying animals. The resulting picture reflects not only upon the questions that are of interest in current pure and applied research, but also upon the experimental techniques that are available to answer them. Doubtless, many new questions will present themselves as the scope and performance of our experimental toolbox develops over the coming years.

  14. Animal production and health newsletter. No. 27

    International Nuclear Information System (INIS)

    The news letter reports workshops and training events in the areas of animal diseases and application of ELISA and radioimmunoassay techniques. It also describes existing and future coordinated research programs in animal production and health

  15. Modeling Investigation of Spring Chinook Salmon Habitat in San Joaquin River Restoration Program

    Science.gov (United States)

    Liu, L.; Ramires, J.

    2013-12-01

    -averaged mathematic model is developed to simulate and predict the hydrodynamic conditions (e.g., current velocity, water surface elevation, etc.) of different alternatives and incorporate the disengaged portion of the SJR. The 2-D model will facilitate to better investigate flow features which are essential to the SJRRP. Flow simulations will allow for the exploration of flow patterns and enable the users to compare each alternative. By simulating and predicting flow conditions of each alternative, this project may offer an insightful understanding of the hydrodynamic occurrence of river alterations and aid in analyzing the passage for Chinook salmon. Key words: modeling; habitat; restoration

  16. Investigation and Analysis on Current Condition of Medical Ethics Consciousness in Animal Experiments in Nursing Students%医护学生在动物实验中的伦理意识调查和分析

    Institute of Scientific and Technical Information of China (English)

    潘丽; 涂腊根; 江婉明; 钟翠芬; 阳小雅; 林小珊

    2013-01-01

    Objective:To investigate the status of current ethical attitudes and animal ethics education in animal experiments in medical nursing students and to discuss and find the methods for solving their psychological confusions. Methods;The self - designed questionnaire was used in 247 medical nursing students. The content involves attitudes toward animal experiments, the understanding of animal protection, present situation of ethical consciousness in animal experiments and the understanding of relationships between animal experiments and clinical work, and part of the students reveived psychological interview. Results: 64. 7% of the nursing students accept animal experiments, and 35. 3% of the medical students feel confused or direct against animal experiments. Ethical education in animal experiments was at shortage, most students were not clear for the purpose of opening animal experiment and how to study and so forth. Conclusion; Teachers should help medical students to analyze the rationality of the animal experiments; doing more work in animal ethical regulations propaganda; continuous research for nursing experimental projects.%目的 了解医护学生对于动物实验的态度和动物伦理教育的现状,探讨解决医护学生心理困惑的途径及方法.方法 采用自制调查问卷的方法,对247名医护学生进行问卷调查,调查内容涉及医护学生对动物实验的基本看法、对实验动物保护法规的了解、医护学生动物实验的伦理意识现状以及对于动物实验与临床工作的关系四个方面,并对部分医护学生进行心理访谈.结果 64.7%的医护学生接受动物实验,而35.3%的医护学生对此感到困惑或直接反对动物实验.医护学生在动物实验中的伦理教育缺失严重,大部分医护学生对于开设动物实验的目的、如何进行学习等目标不明确.结论 教师必须帮助医护学生分析动物实验的合理性与不合理性;做好动物伦理法规

  17. Animal Drug Safety FAQs

    Science.gov (United States)

    ... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Animal & Veterinary Home Animal & Veterinary Safety & Health Frequently Asked Questions Animal Drug Safety Frequently Asked Questions Share Tweet Linkedin ...

  18. Investigation of the anti-inflammatory, analgesic and antipyretic activities of the extracts from the rhizome of Dioscorea membranacea Pierre in experimental animals

    Directory of Open Access Journals (Sweden)

    Pisit Bouking

    2007-03-01

    Full Text Available The effects of the ethanol and aqueous extracts from the rhizome of Dioscorea membranacea Pierre (D. membranacea on inflammatory response using carrageenin-induced paw edema in rats, were examined. Antinociceptive activity using writhing, hot plate and formalin test in mice and the antipyretic activity in yeast-induced fever in rats, were also examined. Oral administration of the ethanol extract at the dose of 1600 mg/kg significantly decreased the paw edema induced by carrageenin in rats. The aqueous extract (1600 mg/kg also significantly suppressed the carrageenin-induced paw edema in rats. The ethanol extract had no significant effects on antinociceptive response in writhing, formalin and hot plate tests and antipyretic activities in yeast-induced fever in rats. No significant effects on writhing test and yeast-induced fever were observed after oral administration of the aqueous extract in experimental animals. These results suggest that the ethanol and aqueous extracts of D. membranacea rhizome possess anti-inflammatory action but no analgesic or antipyretic actions and their anti-inflammatory action may act at some site(s of action or inhibit of some inflammatory mediators, which is different from the action of aspirin.

  19. Animal Testing

    Science.gov (United States)

    Moretto, Johnny; Chauffert, Bruno; Bouyer, Florence

    The development of a new anticancer drug is a long, complex and multistep process which is supervised by regulatory authorities from the different countries all around the world [1]. Application of a new drug for admission to the market is supported by preclinical and clinical data, both including the determination of pharmacodynamics, toxicity, antitumour activity, therapeutic index, etc. As preclinical studies are associated with high cost, optimization of animal experiments is crucial for the overall development of a new anticancer agent. Moreover, in vivo efficacy studies remain a determinant panel for advancement of agents to human trials and thus, require cautious design and interpretation from experimental and ethical point of views.

  20. Animated war

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2012-01-01

    in production: Gzim Rewind (Sweden, 2011) by Knutte Wester, and In-World War (USA, expected 2011) by DJ Bad Vegan. These films have themes of war and include film scenes that are ‘machinima’ (real-time animation made in 3D graphic environments) within live action film scenes. Machinima harnesses...... DIY multimedia storytellers explore new ways to tell and to ‘animate’ stories. The article contains four parts: introduction to machinima and the notions of resemiosis and authorial practice, presentation of DIY filmmaking as a practice that intertwines with new networked economics, analysis...

  1. 78 FR 41401 - Agency Information Collection Activities; Proposed Collection; Comment Request; Draft Animal Feed...

    Science.gov (United States)

    2013-07-10

    ... Collection; Comment Request; Draft Animal Feed Regulatory Program Standards; Availability AGENCY: Food and... associated with the draft Animal Feed Regulatory Program Standards (AFRPS). The draft feed standards are... appropriate, and other forms of information technology. Draft Animal Feed Regulatory Program...

  2. 国家动物源细菌耐药性监测工作的探讨和建议%Discussion and Suggestion on the National Antimicrobial Resistance Monitoring and Surveillance Program in Animals

    Institute of Scientific and Technical Information of China (English)

    顾欣; 金凌艳; 蔡金华; 刘雅妮; 王蓓

    2009-01-01

    The foreign profile of antimicrobial resistance monitoring and surveillance program in animal, and the purpose of resistance monitoring and surveillance program were described. A variety of factors to be considered for resistance monitoring and surveillance program were introduced and discussed, including the animal species, food products, Sampling strategies, specimens collecting, bacterial species, antimicrobials, standardized susceptibility testing, quality control, database design and recording, report and analysis of result. Suggestion was pointed out about antimicrobial resistance monitoring and surveillance program in the future.%介绍了国外动物源细菌耐药性监测工作的情况及目标,对我国的动物源细菌耐药性监测工作需考虑的许多因素进行了介绍和讨论,包括动物品种、食品、采样方法、样本的收集、细菌品种、抗菌药物、标准药敏试验法、质控、结果记录和数据库设计、报告和结果分析等,并对今后的动物源细菌耐药性监测工作提出了建议.

  3. Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo.

    Directory of Open Access Journals (Sweden)

    Claudia Laperchia

    Full Text Available Transgenic mice expressing fluorescent proteins in specific cell populations are widely used for in vivo brain studies with two-photon fluorescence (TPF microscopy. Mice of the thy1GFP-M line have been engineered for selective expression of green fluorescent protein (GFP in neuronal populations. Here, we report that TPF microscopy reveals, at the brain surface of these mice, also motile non-neuronal GFP+ cells. We have analyzed the behavior of these cells in vivo and characterized in brain sections their immunophenotype.With TPF imaging, motile GFP+ cells were found in the meninges, subarachnoid space and upper cortical layers. The striking feature of these cells was their ability to move across the brain parenchyma, exhibiting evident shape changes during their scanning-like motion. In brain sections, GFP+ cells were immunonegative to antigens recognizing motile cells such as migratory neuroblasts, neuronal and glial precursors, mast cells, and fibroblasts. GFP+ non-neuronal cells exhibited instead the characteristic features and immunophenotype (CD11c and major histocompatibility complex molecule class II immunopositivity of dendritic cells (DCs, and were immunonegative to the microglial marker Iba-1. GFP+ cells were also identified in lymph nodes and blood of thy1GFP-M mice, supporting their identity as DCs. Thus, TPF microscopy has here allowed the visualization for the first time of the motile behavior of brain DCs in situ. The results indicate that the thy1GFP-M mouse line provides a novel animal model for the study of subsets of these professional antigen-presenting cells in the brain. Information on brain DCs is still very limited and imaging in thy1GFP-M mice has a great potential for analyses of DC-neuron interaction in normal and pathological conditions.

  4. Investigations of multiresistance to antibiotics and chemotherapeutics and extended spectrum beta: Lactamase effect (ESBL test in strains E.coli and salmonella originating from domestic animals

    Directory of Open Access Journals (Sweden)

    Mišić Dušan

    2006-01-01

    Full Text Available The presence of multiresistance to the effects of antibiotics and chemotherapeutics and extended spectrum beta-lactamase were examined in 45 strains of E. coli and 35 strains of Salmonella. The strains of E. coli originated from several species of domestic animals: dogs, cats, poultry, and cattle, and 30 strains of Salmonella originated from poultry, 4 strains from cattle, and 1 strain from swine. The presence of the following serovarieties was established using serological examinations: Salmonella Enteritidis 17 strains, Salmonella Gallinarum 1 strain, Salmonella Hartford 5 strains, Salmonella Anatum 1 strain, Salmonella Typhimurium 4 strains, Salmonella Agona 1 strain, Salmonella Infantis 1 strain, Salmonella Thompson var. Berlin 1 strain, Salmonella Tennessee 1 strain, Salmonella Senftenberg 1 strain, Salmonella Glostrup 1 strain, and Salmonella Hadar 1 strain. In the examinations of the listed strains we used antibiogram discs of ampicillin, amoxicillin with clavulanic acid, cephalexin, cephtriaxon, cephotaxim, cephtazidime, aztreonam, gentamycin, chloramphenicol, tetracycline, cyprofloxacine, and a combination of sulphamethoxasole and trimethoprim. The lowest prevalence of multiresistance in E. Coli strains to 3 or more antibiotics was established in dogs 20%, and the highest in 60% strains originating from swine. In 62.88% strains of Salmonella we established sensitivity to all applied antibiotics. Resistance was also established in a small number of the examined strains to ampicillin (11 strains, to tetracycline (5 strains, to amoxicillin with clavulanic acid (5 strains, to sulphamethoxasole with trimethoprim (5 strains, to gentamycin (3 strains, and to cloramphenicol (1 strain. Of all the examined strains of Salmonella, 6 strains originating from poultry exhibited multiresistence. The presence of extended spectrum beta-lactamase effects examined using the ESBL test, was not established in strains of E. coli and Salmonella strains.

  5. Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strains Isolated from Farm Animals from 1999 to 2002: Report from the Japanese Veterinary Antimicrobial Resistance Monitoring Program

    OpenAIRE

    Kojima, Akemi; Ishii, Yoshikazu; Ishihara, Kanako; Esaki, Hidetake; Asai, Tetsuo; Oda, Chitose; Tamura, Yutaka; Takahashi, Toshio; Yamaguchi, Keizo

    2005-01-01

    A nationwide surveillance for antimicrobial susceptibility in Escherichia coli strains isolated from food-producing animals in Japan was conducted from 1999 to 2002. Eighteen cefazolin-resistant E. coli strains were isolated from broilers. Six were CTX-M-type producing, and eight were CMY-2 producing, while eight had mutations at the ampC promoter region.

  6. CGRO Guest Investigator Program

    Science.gov (United States)

    Begelman, Mitchell C.

    1998-01-01

    This grant had as its main goal the reduction and analysis of the archival data for blazars collected (primarily) by the EGRET instrument, interpretation of these data in the context of current theoretical models, and development of new theoretical models for blazar jets.

  7. Healthy Choices Afterschool: Investigation of the Alignment of Physical Activity and Nutrition Programs/Curricula and the National Afterschool Association Program Standards

    Science.gov (United States)

    Hall, Georgia; Gruber, Diane

    2006-01-01

    This document reports on physical activity and nutrition curriculum choices for afterschool programs, linking with the National Afterschool Association Program Standards. This project was stimulated by the national concern for child and youth obesity and the valuable role out-of-school time programs can fulfill in helping to address the crisis.…

  8. Subsurface Investigations Program at the Radioactive Waste Management Complex of the Idaho National Engineering Laboratory: Annual progress report, FY-1987

    International Nuclear Information System (INIS)

    The Subsurface Investigations Program is obtaining program objectives of a field calibration of a model to predict long-term radionuclide migration and measurement of the actual migration to date. Three deep boreholes were drilled at the Radioactive Waste Management Complex (RWMC) to collect sample material for evaluation of radionuclide content in the interbeds, to determine geologic and hydrologic characteristics of the sediments, and to provide monitoring sites for moisture movement in these sediments. Suction lysimeters and heat dissipation sensors were installed in two deep boreholes to collect moisture data. Data from the moisture sensing instruments installed at the RWMC continued to be collected during FY-1987. Because of the large volume of collected data, the RWMC Data Management System was developed and implemented to facilitate the storage, retrieval, and manipulation of the database. Work on the Computer Model Development task focused on a detailed review of previous vadose zone modeling studies at INEL, acquisition and installation of a suite of computer models for unsaturated flow and contaminant transport, and preliminary applications of computer models using site-specific data. Computer models installed on the INEL CRAY computer for modeling transport through the subsurface pathway include SEMTRA, FEMTRA, TRACR3D, MAGNUM, and CHAINT. In addition to the major computer models, eight other codes, referred to as support codes and models, have been acquired and implemented. 27 refs., 70 figs., 22 tabs

  9. First intercomparison exercise in the frame of the coordinated investigation program of the IAEA on regional intercomparison of personal dosimetry

    International Nuclear Information System (INIS)

    During the days 7 and 11 of October of 1996 took place in Buenos Aires, Argentina, the first Meeting of the Coordinated Investigation program of the IAEA on Regional Intercomparison of Personal Dosimetry for Latin American. In this meeting participated nine representatives of reference laboratories and of personal dosimetry of the region. Fundamental aspect of personal dosimetry relates with the quantity personal dose equivalent Hp application and the implementation of intercomparison exercise in order to improve the quality of the dose estimation have been discussed. Also lectures carried out by the specialist on Hp and practical aspects of it implementation; answer and calibration according to the ISO 4037; intercomparison methods: procedures and organizations. It was carried out the first intercomparison exercise where the participants collaborated in the preparations and irradiations of personal dosemeters they have brought. (author)

  10. Utilization of the equipment and program cine- and telerecording complex for the high-frequency steel pipe welding investigation

    Science.gov (United States)

    Konovalov, Nikolai A.; Veselovsky, Vladimir B.; Furmanov, Valeri B.; Kovalenko, Vladimir I.; Lakhno, Nikolay I.; Kovika, Nikolai D.; Novikov, Leonid V.; Scherbina, Vadim N.; Zlydennaya, Lyubov M.

    1995-08-01

    With the aim of technological process automatization and control for high-frequency welding of different diameter pipes, the machine-program complex (APC) was designed. APC gives the opportunity to create the cine- and telerecording of process in production conditions at the mill '159-529' of the Novomoskovsky Tube Rolling Mill, Ukraine). With the help of APC in real functioning mill conditions, the character of flashing zone length changing and the angle of convergence depending on pipe welding speed was investigated. Also the zone of jumpers is defined. The comparison of theoretical and experimental data gave an opportunity to define a welding rate which is optimal for the most qualitative values of welded joints in the range of pipe products of mill '159-529'.

  11. Effects of prepartal body condition score and peripartal energy supply of dairy cows on postpartal lipolysis, energy balance and ketogenesis: an animal model to investigate subclinical ketosis.

    Science.gov (United States)

    Schulz, Kirsten; Frahm, Jana; Meyer, Ulrich; Kersten, Susanne; Reiche, Dania; Rehage, Jürgen; Dänicke, Sven

    2014-08-01

    Subclinical ketosis is a metabolic disorder which often goes undiagnosed and leads to constricted performance and an impairment of general condition. In the current study subclinical ketosis was characterised by a β-hydroxybutyrate (BHB) concentration of >1·2 mmol/l in blood serum. To generate this metabolic situation, an animal model was created. The model, based on group-specific interaction of dietary energy supply and body condition, is appropriate for testing the medical effectiveness of treating this kind of ketosis and its concomitants. During the trial, 18 dairy cows (primiparous and pluriparous) were assigned, according to their body condition score (BCS) 6 weeks before expected parturition, to a normal [6.78 MJ net energy for lactation (NEL)/kg dry matter; 20% concentrate] or to a high-energy feeding group (7·71 MJ NEL/kg dry matter; 60% concentrate). Therefore cows with the highest BCS were allocated to the high-energy group to enhance the contrast with the control group. Statistical analysis was done using the MIXED procedure of SAS. Effects were declared significant when P-values were ⩽0.05. Owing to the higher energy concentration and dry matter intake, the energy intake and balance was significantly higher in the high-energy feeding group, with strong effects on lipid metabolism and health in blood and liver post partum. Within the first 2 weeks after calving, 8 out of 9 cows (89%) of the high-energy group had BHB values indicative of subclinical ketosis. These cows also had significantly higher values of non-esterified fatty acids (NEFA), aspartate transaminase (AST) and glutamate dehydrogenase (GLDH) post partum, as well as a raised total lipid content of the liver. RQUICKI, a calculated parameter which is based on serum concentrations of glucose, insulin and NEFA to assess the insulin sensitivity, was not affected by treatment. Therefore, RQUICKI does not seem to be the right parameter for diagnosing decreased insulin sensitivity in cows

  12. Quality assurance/quality control summary report for Phase 1 of the Clinch River remedial investigation. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Holladay, S.K.; Bevelhimer, M.S.; Brandt, C.C. [and others

    1994-07-01

    The Clinch River Remedial Investigation (CRRI) is designed to address the transport, fate, and distribution of waterborne contaminants released from the US Department of Energy Oak Ridge Reservation and to assess potential risks to human health and the environment associated with these contaminants. Primary areas of investigation are Melton Hill Reservoir, the Clinch River from Melton Hill Dam to its confluence with the Tennessee River, Poplar Creek, and Watts Bar Reservoir. Phase 1 of the CRRI was a preliminary study in selected areas of the Clinch River/Watts Bar Reservoir. Fish, sediment, and water samples were collected and analyzed for inorganic, organic, and radiological parameters. Phase 1 was designed to (1) obtain high-quality data to confirm existing historical data for contaminant levels; (2) determine the range of contaminant concentrations present in the river-reservoir system; (3) identify specific contaminants of concern; and (4) establish the reference (background) concentrations for those contaminants. Quality assurance (QA) objectives for Phase I were that (1) scientific data generated would withstand scientific scrutiny; (2) data would be gathered using appropriate procedures for field sampling, chain-of-custody, laboratory analyses, and data reporting; and (3) data would be of known precision and accuracy. These objectives were met through the development and implementation of (1) a QA oversight program of audits and surveillances; (2) standard operating procedures accompanied by a training program; (3) field sampling and analytical laboratory quality control requirements; (4) data and records management systems; and (5) validation of the data by an independent reviewer. Approximately 1700 inorganic samples, 1500 organic samples, and 2200 radiological samples were analyzed and validated. The QA completeness objective for the project was to obtain valid analytical results for at least 95% of the samples collected.

  13. Animal Intuitions.

    Science.gov (United States)

    Kaebnick, Gregory E

    2016-07-01

    As described by Lori Gruen in the Perspective column at the back of this issue, federally supported biomedical research conducted on chimpanzees has now come to an end in the United States, although the wind-down has taken longer than expected. The process began with a 2011 Institute of Medicine report that set up several stringent criteria that sharply limited biomedical research. The National Institutes of Health accepted the recommendations and formed a committee to determine how best to implement them. The immediate question raised by this transition was whether the IOM restrictions should be extended in some form to other nonhuman primates-and beyond them to other kinds of animals. In the lead article in this issue, Anne Barnhill, Steven Joffe, and Franklin Miller consider the status of other nonhuman primates. PMID:27417859

  14. An Investigation of an Arts Infusion Program on Creative Thinking, Academic Achievement, Affective Functioning, and Arts Appreciation of Children at Three Grade Levels.

    Science.gov (United States)

    Luftig, Richard L.

    2000-01-01

    Investigates the effects of an arts infusion program (SPECTRA+) on the creative thinking, academic achievement, self-esteem, locus of control, and appreciation of the arts by school children (n=615). Reports that SPECTRA+ program children scored higher than the control group in creativity, self-esteem, and arts appreciation, while data for…

  15. Animal models in epigenetic research: institutional animal care and use committee considerations across the lifespan.

    Science.gov (United States)

    Harris, Craig

    2012-01-01

    The rapid expansion and evolution of epigenetics as a core scientific discipline have raised new questions about how endogenous and environmental factors can inform the mechanisms through which biological form and function are regulated. Existing and proposed animal models used for epigenetic research have targeted a myriad of health and disease endpoints that may be acute, chronic, and transgenerational in nature. Initiating events and outcomes may extend across the entire lifespan to elicit unanticipated phenotypes that are of particular concern to institutional animal care and use committees (IACUCs). The dynamics and plasticity of epigenetic mechanisms produce effects and consequences that are manifest differentially within discreet spatial and temporal contexts, including prenatal development, stem cells, assisted reproductive technologies, production of sexual dimorphisms, senescence, and others. Many dietary and nutritional interventions have also been shown to have a significant impact on biological functions and disease susceptibilities through altered epigenetic programming. The environmental, chemical, toxic, therapeutic, and psychosocial stressors used in animal studies to elicit epigenetic changes can become extreme and should raise IACUC concerns for the well-being and proper care of all research animals involved. Epigenetics research is rapidly becoming an integral part of the search for mechanisms in every major area of biomedical and behavioral research and will foster the continued development of new animal models. From the IACUC perspective, care must be taken to acknowledge the particular needs and concerns created by superimposition of epigenetic mechanisms over diverse fields of investigation to ensure the proper care and use of animals without impeding scientific progress.

  16. The National Cancer Institute's PREVENT Cancer Preclinical Drug Development Program: overview, current projects, animal models, agent development strategies, and molecular targets.

    Science.gov (United States)

    Shoemaker, Robert H; Suen, Chen S; Holmes, Cathy A; Fay, Judith R; Steele, Vernon E

    2016-02-01

    The PREVENT Cancer Preclinical Drug Development Program (PREVENT) is a National Cancer Institute, Division of Cancer Prevention (NCI, DCP)-supported program whose primary goal is to bring new cancer preventive interventions (small molecules and vaccines) and biomarkers through preclinical development towards clinical trials by creating partnerships between the public sector (eg, academia, industry) and DCP. PREVENT has a formalized structure for moving interventions forward in the prevention pipeline using a stage-gate process with go/no go decision points along the critical path for development. This review describes the structure of the program, its focus areas, and provides examples of projects currently in the pipeline.

  17. The National Cancer Institute's PREVENT Cancer Preclinical Drug Development Program: overview, current projects, animal models, agent development strategies, and molecular targets.

    Science.gov (United States)

    Shoemaker, Robert H; Suen, Chen S; Holmes, Cathy A; Fay, Judith R; Steele, Vernon E

    2016-02-01

    The PREVENT Cancer Preclinical Drug Development Program (PREVENT) is a National Cancer Institute, Division of Cancer Prevention (NCI, DCP)-supported program whose primary goal is to bring new cancer preventive interventions (small molecules and vaccines) and biomarkers through preclinical development towards clinical trials by creating partnerships between the public sector (eg, academia, industry) and DCP. PREVENT has a formalized structure for moving interventions forward in the prevention pipeline using a stage-gate process with go/no go decision points along the critical path for development. This review describes the structure of the program, its focus areas, and provides examples of projects currently in the pipeline. PMID:26970137

  18. Bioethical Problems: Animal Welfare, Animal Rights.

    Science.gov (United States)

    March, B. E.

    1984-01-01

    Discusses various bioethical issues and problems related to animal welfare and animal rights. Areas examined include: Aristotelian views; animal welfare legislation; Darwin and evolutionary theory; animal and human behavior; and vegetarianism. A 14-point universal declaration of the rights of animals is included. (JN)

  19. A curated transcriptome dataset collection to investigate the functional programming of human hematopoietic cells in early life.

    Science.gov (United States)

    Rahman, Mahbuba; Boughorbel, Sabri; Presnell, Scott; Quinn, Charlie; Cugno, Chiara; Chaussabel, Damien; Marr, Nico

    2016-01-01

    Compendia of large-scale datasets made available in public repositories provide an opportunity to identify and fill gaps in biomedical knowledge. But first, these data need to be made readily accessible to research investigators for interpretation. Here we make available a collection of transcriptome datasets to investigate the functional programming of human hematopoietic cells in early life. Thirty two datasets were retrieved from the NCBI Gene Expression Omnibus (GEO) and loaded in a custom web application called the Gene Expression Browser (GXB), which was designed for interactive query and visualization of integrated large-scale data. Quality control checks were performed. Multiple sample groupings and gene rank lists were created allowing users to reveal age-related differences in transcriptome profiles, changes in the gene expression of neonatal hematopoietic cells to a variety of immune stimulators and modulators, as well as during cell differentiation. Available demographic, clinical, and cell phenotypic information can be overlaid with the gene expression data and used to sort samples. Web links to customized graphical views can be generated and subsequently inserted in manuscripts to report novel findings. GXB also enables browsing of a single gene across projects, thereby providing new perspectives on age- and developmental stage-specific expression of a given gene across the human hematopoietic system. This dataset collection is available at: http://developmentalimmunology.gxbsidra.org/dm3/geneBrowser/list. PMID:27347375

  20. Ca2+ influx and efflux in animal cells in the presence of panax notoginseng extracts: investigated by using 45Ca as a radioactive tracer

    International Nuclear Information System (INIS)

    In this paper, the influence of extracts of Panax notoginseng on Ca2+ influx and efflux in isolated rat visceral organs was investigated by using 45Ca as a radioactive tracer. The results indicated that both extracts, the total flavonoids and total saponins of Panax notoginseng had significant influence on Ca2+ influx and efflux in the isolated rat aorta, heart, and kidney, in those organs it could markedly block 45Ca entering into cell and could facilitate efflux of intracellular Ca2+. Compared with the total flavonoids, total saponins had stronger role in the regulation of Ca2+ influx and efflux. Also, regulation effects of Ca2+ influx and efflux of the total saponins were compared with positive drug Verapamil, or even better. This implies that the total flavonoids and total saponins of Panax notoginseng have calcium antagonistic effect, and both may be the active ingredients in Panax notoginseng for coronary heart disease treatment. (authors)

  1. Animal production and health newsletter. No. 25

    International Nuclear Information System (INIS)

    In addition to announcements of forthcoming training and meeting programs, as well as status of coordinated research programs, this issue highlights application of molecular biology in diagnosis of animal diseases in developing countries

  2. Animal welfare: an animal science approach.

    Science.gov (United States)

    Koknaroglu, H; Akunal, T

    2013-12-01

    Increasing world population and demand for animal-derived protein puts pressure on animal production to meet this demand. For this purpose animal breeding efforts were conducted to obtain the maximum yield that the genetic makeup of the animals permits. Under the influence of economics which is the driving force behind animal production, animal farming became more concentrated and controlled which resulted in rearing animals under confinement. Since more attention was given on economics and yield per animal, animal welfare and behavior were neglected. Animal welfare which can be defined as providing environmental conditions in which animals can display all their natural behaviors in nature started gaining importance in recent years. This does not necessarily mean that animals provided with good management practices would have better welfare conditions as some animals may be distressed even though they are in good environmental conditions. Consumers are willing to pay more for welfare-friendly products (e.g.: free range vs caged egg) and this will change the animal production practices in the future. Thus animal scientists will have to adapt themselves for the changing animal welfare rules and regulations that differ for farm animal species and countries. In this review paper, animal welfare is discussed from an animal science standpoint.

  3. Animated nature

    International Nuclear Information System (INIS)

    Animated nature is educational-training project pronounced by the Slovak Environmental Agency (SAZP) in cooperation with Field Studies Council form Great Britain and financial support of Darwin Initiative and Slovensky plynarensky priemysel, s.p. In the present time this is ultimate and the most successful children's project aimed on mapping and protection of biodiversity in Europe. Activity in project is spare-time and therefore is voluntary. The interest territory is a natural as well as cultural landscape in vicinity of a school or other organisation, habitation and so on. In the project work schoolchildren at the age from 10 till 15 years. Leaders of work-groups are student of secondary schools and universities, teachers, professional workers of state and non-governmental organisation and parents. In one group works approximately 10 children. Each group which has send to SAZP result of biodiversity mapping, cost free obtained data base CD - Detske mapy biodiverzity (Children's maps of biodiversity) and so they were informed about results of all groups frame: within the frame of Slovakia. Results of activities of this project in 2001-2004 and perspectives for 2005-2006 years are discussed

  4. Animating Brains

    Science.gov (United States)

    Borck, Cornelius

    2016-01-01

    A recent paper famously accused the rising field of social neuroscience of using faulty statistics under the catchy title ‘Voodoo Correlations in Social Neuroscience’. This Special Issue invites us to take this claim as the starting point for a cross-cultural analysis: in which meaningful ways can recent research in the burgeoning field of functional imaging be described as, contrasted with, or simply compared to animistic practices? And what light does such a reading shed on the dynamics and effectiveness of a century of brain research into higher mental functions? Reviewing the heated debate from 2009 around recent trends in neuroimaging as a possible candidate for current instances of ‘soul catching’, the paper will then compare these forms of primarily image-based brain research with older regimes, revolving around the deciphering of the brain’s electrical activity. How has the move from a decoding paradigm to a representational regime affected the conceptualisation of self, psyche, mind and soul (if there still is such an entity)? And in what ways does modern technoscience provide new tools for animating brains? PMID:27292322

  5. Proceedings of the SERI Biomass Program Principal Investigators' Review Meeting: Aquatic Species Program Reports; 23-25 June 1982, Washington, DC

    Energy Technology Data Exchange (ETDEWEB)

    1982-12-01

    The Aquatic Species Program (ASP) is concerned with how plant biomass that naturally occurs in wetland or submerged areas is utilized. Processes are being developed in this program to make use of those aquatic species, capitalizing on their inherent capacity for rapid growth as well as on their extraordinary chemical compositions.

  6. Environmental Restoration Program pollution prevention performance measures for FY 1993 and 1994 remedial investigations: Generator training manual

    International Nuclear Information System (INIS)

    This computer-based program is designed to help waste generators in the Environmental Restoration (ER) Program prevent pollution at the DOE Oak Ridge Field Office (DOE-OR) facilities in Oak Ridge, Paducah, and Portsmouth. The Numerical Scoring System (NSS) is an interactive system designed to maintain data on ER Program pollution prevention efforts and to measure the success of these efforts through the ER Program life cycle

  7. Environmental Restoration Program pollution prevention performance measures for FY 1993 and 1994 remedial investigations: Generator training manual

    Energy Technology Data Exchange (ETDEWEB)

    1993-03-01

    This computer-based program is designed to help waste generators in the Environmental Restoration (ER) Program prevent pollution at the DOE Oak Ridge Field Office (DOE-OR) facilities in Oak Ridge, Paducah, and Portsmouth. The Numerical Scoring System (NSS) is an interactive system designed to maintain data on ER Program pollution prevention efforts and to measure the success of these efforts through the ER Program life cycle.

  8. An Investigation of How Culture Shapes Curriculum in Early Care and Education Programs on a Native American Indian Reservation: "The Drum Is Considered the Heartbeat of the Community"

    Science.gov (United States)

    Gilliard, Jennifer L.; Moore, Rita A.

    2007-01-01

    This article investigates how culture shapes instruction in three early care and education programs on the Flathead Indian Reservation. Interviews with eight early childhood teachers as well as classroom observations were conducted. The investigation is framed by the following research question: How does the culture of the family and community…

  9. CRITTER: A database for managing research animals

    OpenAIRE

    Lees, V. Wayne; Lukey, Claire; Orr, Richard

    1993-01-01

    We describe CRITTER, a computer database program for managing research animals. We designed it especially for institutions which operate health surveillance plans, such as specific pathogen-free schemes. Because CRITTER can be used to record any type of test result in any species of animal, it can be customized to suit each institution and its management protocol. In addition to maintaining a current inventory of each individual animal and its location, the program retains historical informat...

  10. Metacognition in animals

    OpenAIRE

    Crystal, Jonathon D.; Foote, Allison L.

    2009-01-01

    Metacognition is thinking about thinking. There is considerable interest in developing animal models of metacognition to provide insight about the evolution of mind and a basis for investigating neurobiological mechanisms of cognitive impairments in people. Formal modeling of low-level (i.e., alternative) mechanisms has recently demonstrated that prevailing standards for documenting metacognition are inadequate. Indeed, low-level mechanisms are sufficient to explain data from existing methods...

  11. Animation of boom failure processes

    International Nuclear Information System (INIS)

    Computer animations of oil boom failure mechanisms were discussed. The animations are useful in demonstrating the transient processes of boom failure. They consist of a series of images obtained from the graphical output of a computational fluid dynamics program, FLUENT, while the modeling is based on boom failure experiments carried out in flowing water channels. The animations can be viewed on a PC running under Windows '95. Three types of failures are presented, i. e. drainage failure, droplet entrainment and critical accumulation. 11 refs., 3 figs

  12. The wild animal as a research animal

    NARCIS (Netherlands)

    Swart, JAA

    2004-01-01

    Most discussions on animal experimentation refer to domesticated animals and regulations are tailored to this class of animals. However, wild animals are also used for research, e. g., in biological field research that is often directed to fundamental ecological-evolutionary questions or to conserva

  13. Society’s attitude towards animals

    OpenAIRE

    Brčinović, Brigita

    2014-01-01

    In my diploma thesis I decided to write about relationship between society and animals, mostly because I love animals very much. Although slow, I think that relationship between society and animals is changing to better in last few years. In lots of cases a child is growing up with an animal since his young ages, animals are included in preschool programs in different ways, and not rarely children have animals on visit or even in their own group in kindergarden. Also, in specialized literatur...

  14. RCRA Facility Investigation report for Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee. Volume 3, Appendixes 1 through 8: Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    This report presents compiled information concerning a facility investigation of waste area group 6(WAG-6), of the solid waste management units (SWMU`S) at Oak Ridge National Laboratory (ORNL). The WAG is a shallow ground disposal area for low-level radioactive wastes and chemical wastes. The report contains information on hydrogeological data, contaminant characterization, radionuclide concentrations, risk assessment from doses to humans and animals and associated cancer risks, exposure via food chains, and historical data. (CBS)

  15. Animation of Antimicrobial Resistance

    Science.gov (United States)

    ... Veterinary Home Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it ... Veterinary Medicine is cited as the corporate author. Animation Animation of Antimicrobial Resistance (WMV - 19.2MB) 9: ...

  16. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Animal & Veterinary Home Animal & Veterinary Safety & ... Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products

  17. An Investigation of a Culturally Responsive Approach to Science Education in a Summer Program for Marginalized Youth

    Science.gov (United States)

    Garvin, Brittany A.

    There have been numerous calls and efforts made to provide states, school districts, and communities needed financial support to increase and enhance access to and opportunities in Science, Technology, Engineering, and Math (STEM) related disciplines for marginalized populations (Tyson, Lee, & Hanson, 2007; Caldwell & Siwatu, 2003). As the challenge to better educate students of color and poor students intensifies, the need to provide equitable science learning experiences for all students aimed at scientific literacy and STEM also becomes critical. Thus the need to provide summer science enrichment programs where students engage in scientific experimentation, investigation, and critical thinking are vital to helping students who have been traditionally marginalized achieve success in school science and enter the science career pipeline. This mixed methods study examined the impact of a culturally responsive approach on student attitudes, interests in science education and STEM careers, and basic science content knowledge before and after participation in an upward bound summer program. Quantitative results indicated using a culturally responsive approach to teach science in an informal learning space significantly increases student achievement. Students receiving culturally responsive science instruction exhibited statistically significant increases in their posttest science scores compared to pretest science scores, M = 0.376, 95% CI [0.266, 0.487], t (10) = 7.610, p < 0.001. Likewise, students receiving culturally responsive science instruction had a significantly higher interest in science (M = 1.740, SD = 0.548) and STEM careers, M = 0.597, 95% CI [0.276, 0.919], p = 0.001. The qualitative data obtained in this study sought to gain a more in-depth understanding of the impact of a culturally responsive approach on students' attitudes, interests in science and STEM careers. Findings suggest providing students the opportunity to do and learn science utilizing a

  18. Investigating Value Creation in a Community of Practice with Social Network Analysis in a Hybrid Online Graduate Education Program

    Science.gov (United States)

    Cowan, John E.; Menchaca, Michael P.

    2014-01-01

    This study reports an analysis of 10?years in the life of the Internet-based Master in Educational Technology program (iMET) at Sacramento State University. iMET is a hybrid educational technology master's program delivered 20% face to face and 80% online. The program has achieved a high degree of success, with a course completion rate of 93%…

  19. Animal models for investigating chronic pancreatitis

    OpenAIRE

    Aghdassi Alexander A; Mayerle Julia; Christochowitz Sandra; Weiss Frank U; Sendler Matthias; Lerch Markus M

    2011-01-01

    Abstract Chronic pancreatitis is defined as a continuous or recurrent inflammatory disease of the pancreas characterized by progressive and irreversible morphological changes. It typically causes pain and permanent impairment of pancreatic function. In chronic pancreatitis areas of focal necrosis are followed by perilobular and intralobular fibrosis of the parenchyma, by stone formation in the pancreatic duct, calcifications in the parenchyma as well as the formation of pseudocysts. Late in t...

  20. Source evaluation report phase 2 investigation: Limited field investigation. Final report: United States Air Force Environmental Restoration Program, Eielson Air Force Base, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    1994-10-01

    This report describes the limited field investigation work done to address issues and answer unresolved questions regarding a collection of potential contaminant sources at Eielson Air Force Base (AFB), near Fairbanks, Alaska. These sources were listed in the Eielson AFB Federal Facility Agreement supporting the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) cleanup of the base. The limited field investigation began in 1993 to resolve all remaining technical issues and provide the data and analysis required to evaluate the environmental hazard associated with these sites. The objective of the limited field investigation was to allow the remedial project managers to sort each site into one of three categories: requiring remedial investigation/feasibility study, requiring interim removal action, or requiring no further remedial action.

  1. Decerebrate rigidity in animals.

    Science.gov (United States)

    Davis, R A; Davis, L

    1981-07-01

    Decerebrate rigidity (DR) in animals is caused by a release of spinal neurons from supraspinal inhibition, which results in a caricature of reflex standing and includes tonic neck and labyrinthine reflexes. The reticular formation, cerebellum, vestibular complex, spinal cord, and muscle spindle system and their neurophysiological interaction are critical to DR. Its discovery and investigation were essential to Sherrington's concept of the integrative action of the nervous system. There are two types of DR with different anatomical and physiological bases. Intercollicular decerebration yields rigidity in extensor muscles that results from bilateral destruction of the central tegmental tracts, is abolished by posterior root section, and is due to a facilitation of gamma motoneuron discharge (gamma animal). Anemic decerebration is characterized by excessive extensor rigidity, depends upon the release of tonic labryinthine reflexes from cerebellar inhibition, is independent of posterior root section, and is caused by excessive alpha motoneuron discharge (alpha animal). DR has provided an insight into the mechanisms of posture and standing, but the correlation of laboratory observations and results from animals to humans must be made with caution.

  2. "Seroepidemiological Survey of Brucellosis Among Animal Farmers of Yazd Province"

    Directory of Open Access Journals (Sweden)

    MH Salari

    2002-08-01

    Full Text Available Brucellosis has remained a great problem of health in most of countries, which have failed in control of zoonosis infections. This disease is caused by species of Brucella and usually is transferred from animals to humans. The purpose of this study was to investigate the seroprevalence of brucellosis among animal farmers of Yazd province. In this descriptive study, 933 animal farmers were investigated by serological tests and blood culture method. Then the data were analyzed by SPPS statistical program. The results showed that the frequency distribution of seropositive cases by MAT and STAT were 35 (3.2%; 25 (2.7% males and 10 (1.1% females. The highest and lowest incidences of seropositive cases were among age group of 21-30 (1% and more than 60 (0.3% years old, respectively. Of the 35 seropositive cases, 2MET positive were 5 (0.5%, while all blood cultures were negative.

  3. Seismic structural fragility investigation for the Zion Nuclear Power Plant. Seismic safety margins research program (phase 1)

    International Nuclear Information System (INIS)

    An evaluation of the seismic capacity of the essential structures for the Zion Nuclear Power Plant in Zion, Illinois, was conducted as part of the Seismic Safety Margins Research Program (SSMRP). The structures included the reactor containment building, the turbine/auxiliary building, and the crib house (intake structure). The evaluation was devoted to seismically induced failures rather than those resulting from combined Loss of Coolant Accident (LOCA) or other extreme load combinations. The seismic loads used in the investigation were based on elastic analyses. The loads for the reactor containment and turbine/auxiliary buildings were developed by Lawrence Livermore Laboratory using time history analyses. The loads used for the crib house were the original seismic design loads developed by Sargent and Lundy. No non-linear seismic analyses were conducted. The seismic capacity of the structures accounted for the actual concrete and steel material properties including the aging of the concrete. Median centered properties were used throughout the evaluation including levels of damping considered appropriate for structures close to collapse as compared to the more conservative values used for design. The inelastic effects were accounted for using ductility modified response spectrum techniques based on system ductility ratios expected for structures near collapse. Sources of both inherent randomness and uncertainties resulting from lack of knowledge or approximations in analytical modelling were considered in developing the dispersion of the structural dynamic characteristics. Coefficients of variation were developed assuming lognormal distributions for all variables. The earthquake levels for many of the seismically induced failure modes are so high as to be considered physically incredible. (author)

  4. An Exploratory Investigation into the Relationship between Television Program Preference and Emotion-Eliciting Qualities--A New Theoretical Perspective.

    Science.gov (United States)

    Christ, William G.; Biggers, Thompson

    1984-01-01

    This exploratory study applies Mehrabian and Russell's newly formulated theory of emotion to the problem of explaining television program preference. Results suggest that emotion-eliciting qualities (pleasure, arousal, and dominance) can account for up to 43 percent of the program preference of television viewers. (PD)

  5. An Investigation of Basic and Borderline Proficient Students' Comprehension Reading Achievement Using the Read 180 Computerized Instructional Program

    Science.gov (United States)

    Piper, Deborah L.

    2013-01-01

    The purpose of this study was to see if students made gains in reading achievement in the area of reading comprehension by having used a computerized reading instructional program entitled "READ 180RTM." The researcher included a qualitative component to gather teacher and parent perceptions of the use of this program. The theoretical…

  6. Analytical investigation of efficiency and performance limits in klystron amplifiers using multidimensional computer programs; multi-stage depressed collectors; and thermionic cathode life studies

    Science.gov (United States)

    Kosmahl, H. G.

    1980-01-01

    An extensive parametric investigation was performed of the extraction of energy in output gaps of klystron amplifiers, using 3-D computer programs. Due to complexity of the program which used a hydrodynamic, axially and radially deformable disk ring model and the resulting long computing time, the investigation was limited to the output gap, by far the most important and difficult part of the klystron interaction. Results show that, for a confined flow focused beam throughout the penultimate cavity, radial velocities remain very small and the beam is highly laminar. It was, therefore, concluded that possible errors resulting from treating only the output cavity in 3-D would remain small.

  7. Antimicrobial stewardship in small animal veterinary practice

    DEFF Research Database (Denmark)

    Guardabassi, Luca; Prescott, John F

    2015-01-01

    Despite the increasing recognition of the critical role for antimicrobial stewardship in preventing the spread of multidrug-resistant bacteria, examples of effective antimicrobial stewardship programs are rare in small animal veterinary practice. This article highlights the basic requirements...... for establishing stewardship programs at the clinic level. The authors provide suggestions and approaches to overcome constraints and to move from theoretic concepts toward implementation of effective antimicrobial stewardship programs in small animal clinics....

  8. Phoenix Animation Looking North

    Science.gov (United States)

    2008-01-01

    [figure removed for brevity, see original site] Click on image for animation This animation is a series of images, taken by NASA's Phoenix Mars Lander's Surface Stereo Imager, combined into a panoramic view looking north from the lander. The area depicted is beyond the immediate workspace of the lander and shows a system of polygons and troughs that connect with the ones Phoenix will be investigating in depth. The images were taken on sol 14 (June 8, 2008) or the 14th Martian day after landing. The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  9. Animal welfare assessment

    OpenAIRE

    Vučinić Marijana; Lazić Ivana

    2008-01-01

    The paper deals with animal welfare definitions and animal welfare assessment. Animal welfare is a prolonged mental state, resulting from how the animal experiences its environment over time. There are different methods for animal welfare assessment. The four basic criteria for animal welfare assessment are feeding, housing, health and appropriate behavior. Therefore, criteria used to assess animal welfare are not direct measures of the mental state but only parameters that need to be interpr...

  10. Key Factors for Formulation of Immunization Programs in Animal and Poultry Farms%制定养殖场免疫程序应考虑的主要因素

    Institute of Scientific and Technical Information of China (English)

    尹子静; 刘裕田

    2015-01-01

    Vaccination is an effective way for infectious disease prevention and control, and the quality of immunization programs directly determines the immune effect. In this paper,some key factors for formulation of immunization pro-grams in animal and poultry farms are discussed, including local disease situation,antibody level, vaccination routes, vaccine types and properties,breed sources, feeding management level. The immunization programs must be formu-lated according to the local conditions and the key factors mentioned above.%免疫接种是预防控制传染病的有效方法,免疫程序合理与否直接决定到免疫效果,因此养殖场要按照因地制宜的原则,根据本地的疫病种类、疫病流行情况、抗体水平、免疫途径、疫苗种类与性质、种畜禽来源、饲养管理水平等综合因素,科学制定适合本场的免疫程序。

  11. Teaching Translational Research to Medical Students: The New York University School of Medicine's Master's of Science in Clinical Investigation Dual-Degree Program.

    Science.gov (United States)

    Gillman, Jennifer; Pillinger, Michael; Plottel, Claudia S; Galeano, Claudia; Maddalo, Scott; Hochman, Judith S; Cronstein, Bruce N; Gold-von Simson, Gabrielle

    2015-12-01

    To develop the next generation of translational investigators, New York University School of Medicine (NYUSOM) and the NYU-NYC Health and Hospitals Corporation Clinical and Translational Science Institute (NYU-HHC CTSI) developed the Master's of Science in Clinical Investigation dual-degree (MD/MSCI) program. This 5-year program dedicates 1 year to coursework and biomedical research, followed by a medical school/research overlap year, to prepare students for academic research careers. This paper details the MD/MSCI program's curriculum and approach to mentorship, describes the research/professional interests of students, and reports student productivity. In the first 4 years of the program (2010-2014) 20 students were matriculated; 7 (35%) were women, and 12 (60%) research projects were in surgical specialties. To date, 14 students have applied to residency, and half pursued surgical residency programs. Our students have produced 68 accepted abstracts, 15 abstracts in submission, 38 accepted papers, and 24 papers in submission. Despite the time-limited nature of this program, additional training in research design and implementation has promoted a high level of productivity. We conclude that dual-degree training in medicine and translational research is feasible for medical students and allows for meaningful participation in valuable projects. Follow-up is warranted to evaluate the academic trajectory of these students. PMID:26365704

  12. Performance based pay : an empirical investigation of the impact of performance pay increases on perceptions critical to successful merit pay programs

    OpenAIRE

    Vest, Michael J.

    1985-01-01

    The purpose of this study was to investigate the impact of size of performance pay increases on employee perceptions critical to the success of merit pay programs. Perceptions investigated in this study included: 1) instrumentality, 2) expectancy, 3) performance appraisal administration, 4) performance appraisal content, 5) trust in city management, 6) pay communication, and 7) importance of pay. It was hypothesized that individuals who received above average performan...

  13. Modern pulsed spectrometer EPR for longitudinal relaxation time (T1) investigation - computer programs for measurement and data analysis

    International Nuclear Information System (INIS)

    The computerized control and data processing systems for new spectrometer designed for nuclear magnetic resonance studies of biological samples are presented. Both programs were written for INTEL 386 processor and they works under the Windows 3.0 environment

  14. National Weatherization Assistance Program Impact Evaluation: Impact of Exhaust-Only Ventilation on Radon and Indoor Humidity - A Field Investigation

    Energy Technology Data Exchange (ETDEWEB)

    Pigg, Scott [Energy Center of Wisconsin, Madison, WI (United States)

    2014-09-01

    The study described here sought to assess the impact of exhaust-only ventilation on indoor radon and humidity in single-family homes that had been treated by the Weatherization Assistance Program (WAP).

  15. Animal Protection and Animal 'Rights' in Hungary

    OpenAIRE

    Toth, Zoltan J.

    2012-01-01

    In Hungary, the first Act on Animal Protection, which aimed at handling and respecting animals as living creatures capable of feelings and suffering and thus deserving and entitled to protection, was adopted in 1998. Based on this, the Act contains several regulations which ensure that animals are protected against all possible kinds of avoidable physical or mental harm. Furthermore, it prohibits and imposes sanctions for any treatment that causes animals unnecessary suffering. The present st...

  16. Animal rights, animal minds, and human mindreading

    OpenAIRE

    Mameli, M.; Bortolotti, L

    2006-01-01

    Do non‐human animals have rights? The answer to this question depends on whether animals have morally relevant mental properties. Mindreading is the human activity of ascribing mental states to other organisms. Current knowledge about the evolution and cognitive structure of mindreading indicates that human ascriptions of mental states to non‐human animals are very inaccurate. The accuracy of human mindreading can be improved with the help of scientific studies of animal minds. However, the s...

  17. [Animal experimentation, animal welfare and scientific research].

    Science.gov (United States)

    Tal, H

    2013-10-01

    Hundreds of thousands of laboratory animals are being used every year for scientific experiments held in Israel, mostly mice, rats, rabbits, guinea pigs, and a few sheep, cattle, pigs, cats, dogs, and even a few dozen monkeys. In addition to the animals sacrificed to promote scientific research, millions of animals slain every year for other purposes such as meat and fine leather fashion industries. While opening a front against all is an impossible and perhaps an unjustified task, the state of Israel enacted the Animal Welfare (Animal Experimentation) Law (1994). The law aims to regulate scientific animal experiments and to find the appropriate balance between the need to continue to perform animal experiments for the advancement of research and medicine, and at the same time to avoid unnecessary trials and minimize animal suffering. Among other issues the law deals with the phylogenetic scale according to which experimental animals should be selected, experiments for teaching and practicing, and experiments for the cosmetic industry. This article discusses bioethics considerations in animal experiments as well as the criticism on the scientific validity of such experiments. It further deals with the vitality of animal studies and the moral and legal obligation to prevent suffering from laboratory animals. PMID:24660572

  18. [Poultry husbandry and animal health].

    Science.gov (United States)

    Neumann, U

    2003-08-01

    Close interactions are existing between poultry husbandry and poultry health. The more housing systems and the environment of the animals can be controlled, the less the general risk of disorders in poultry flocks--especially of diseases which are caused by the introduction of microoganisms. Resulting deterimental effects will affect not only the animals themselves, but also pose a risk indirectly for humans via food originating from animals under production. Also, by keeping the risk of infections as low as possible, the use of therapeutics can be avoided. This will reduce the risk of residues in food of animal origin. In summary, with all probability open poultry husbandry systems, especially those including free range systems pose increased risks for poultry health and consequently for the quality of food originating from poultry production. At least, those systems require highest standards of biosecurity, defined as management, location, farm layout, cleaning and desinfection incl. pest control programs, immunization and specific veterinary monitoring concepts to prevent infections.

  19. Environmental, Safety, and Health Plan for the remedial investigation/feasibility study at Oak Ridge National Laboratory, Oak Ridge, Tennessee. Revision 1, Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Davis, C. M.; El-Messidi, O. E.; Cowser, D. K.; Kannard, J. R.; Carvin, R. T.; Will, III, A. S.; Clark, Jr., C.; Garland, S. B.

    1993-05-01

    This Environmental, Safety, and Health (ES&H) Plan presents the concepts and methodologies to be followed during the remedial investigation/feasibility study (RI/FS) for Oak Ridge National Laboratory (ORNL) to protect the health and safety of employees, the public, and the environment. This ES&H Plan acts as a management extension for ORNL and Martin Marietta Energy Systems, Inc. (Energy Systems) to direct and control implementation of the project ES&H program. The subsections that follow describe the program philosophy, requirements, quality assurance measures, and methods for applying the ES&H program to individual waste area grouping (WAG) remedial investigations. Hazardous work permits (HWPs) will be used to provide task-specific health and safety requirements.

  20. Game-Based Cognitive-Behavioral Therapy (GB-CBT) Group Program for Children Who Have Experienced Sexual Abuse: A Preliminary Investigation

    Science.gov (United States)

    Misurell, Justin R.; Springer, Craig; Tryon, Warren W.

    2011-01-01

    This preliminary investigation examined the efficacy of a game-based cognitive-behavioral therapy group program for elementary school-aged children who have experienced sexual abuse. Treatment aimed to improve: (a) internalizing symptoms, (b) externalizing behaviors, (c) sexually inappropriate behaviors, (d) social skills deficits, (e) self-esteem…

  1. Investigating the Effectiveness of an Arts-Based and Mindfulness-Based Group Program for the Improvement of Resilience in Children in Need

    Science.gov (United States)

    Coholic, Diana; Eys, Mark; Lougheed, Sean

    2012-01-01

    We discuss preliminary findings from a study that investigated the effectiveness of a Holistic Arts-Based Group Program (HAP) for the development of resilience in children in need. The HAP teaches mindfulness using arts-based methods, and aims to teach children how to understand their feelings and develop their strengths. We assessed the…

  2. A Quasi-Experimental Investigation of How the Gates Millennium Scholars Program Is Related to College Students' Time Use and Activities

    Science.gov (United States)

    DesJardins, Stephen L.; McCall, Brian P.; Ott, Molly; Kim, Jiyun

    2010-01-01

    A national scholarship program provided by the Bill & Melinda Gates Foundation is designed to improve access to and success in higher education for low-income high-achieving minority students by providing them with full tuition scholarships and non-monetary support. We use a regression discontinuity approach to investigate whether the receipt of…

  3. A comparison of the effects of animal dissection and a computer simulation dissection program on students' knowledge of frog anatomy and attitudes toward dissection

    Science.gov (United States)

    Michel-Clark, Isabella

    The purpose of this study was to examine the effectiveness of computer-simulated dissection versus the effectiveness of true dissection related to student achievement and attitude. Student achievement was measured by post-dissection and delayed post-dissection tests which measured students' knowledge on frog anatomy. Students' attitudes were measured by pre-dissection and post-dissection attitude surveys. The sample used consisted of 115 high school biology students from four classes taught by two teachers. The site had a student enrollment of 1243 with a minority population of 58%. Each teacher had one class that conducted a true dissection of a frog and another class that completed the Digital Frog 2 computer simulation program. Each group conducted their dissection for two days and then took a test on a real specimen. Two weeks later, each group was tested again on the same structures that were on the first test. Data were analyzed using t-tests for independent means and Mann-Whitney U tests. Results indicated that students who participated in the true dissection scored significantly higher on both the post and delayed post-dissection achievement tests. The academic achievements were consistent across gender, grade level, and previous science grade. Student attitude was also analyzed by calculating frequencies of the survey questions. Results indicated differences in attitudes between students in the true dissection group versus students in the computer-simulated dissection group.

  4. History of animal bioacoustics

    Science.gov (United States)

    Popper, Arthur N.; Dooling, Robert J.

    2002-11-01

    The earliest studies on animal bioacoustics dealt largely with descriptions of sounds. Only later did they address issues of detection, discrimination, and categorization of complex communication sounds. This literature grew substantially over the last century. Using the Journal of the Acoustical Society of America as an example, the number of papers that fall broadly within the realm of animal sound production, communication, and hearing rose from two in the partial first decade of the journal in the 1930's, to 20 in the 1970's, to 92 in the first 2 years of this millennium. During this time there has been a great increase in the diversity of species studied, the sophistication of the methods used, and the complexity of the questions addressed. As an example, the first papers in JASA focused on a guinea pig and a bird. In contrast, since the year 2000 studies are often highly comparative and include fish, birds, dolphins, dogs, ants, crickets, and snapping shrimp. This paper on the history of animal bioacoustics will consider trends in work over the decades and discuss the formative work of a number of investigators who have spurred the field by making critical theoretical and experimental observations.

  5. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Animal & ... back Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products

  6. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Animal & Veterinary Cosmetics Tobacco Products Animal & Veterinary ... The Food and Drug Administration's (FDA's) Center for Veterinary Medicine (CVM) produced a nine-minute animation explaining how ...

  7. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... 08 Animation of Antimicrobial Resistance (text version) Arabic Translation - Animation of Antimicrobial Resistance (WMV - 19.2MB) Chinese Translation - Animation of Antimicrobial Resistance (WMV - 19.2MB) French ...

  8. Investigation of Neutron-induced Reactions at n_TOF: an Overview of the 2009–2012 Experimental Program

    CERN Document Server

    Guerrero, C; Andrzejewski, J; Audouin, L; Barbagallo, M; Bécares, V; Bečvář, F; Belloni, F; Berthoumieux, E; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviani, M; Calviño, F; Cano-Ott, D; Carrapiço, C; Cerutti, F; Chiaveri, E; Chin, M; Colonna, N; Cortés, G; Cortés-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dressler, R; Dzysiuk, N; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Gunsing, F; Gurusamy, P; Jenkins, D G; Jericha, E; Kadi, Y; Käppeler, F; Karadimos, D; Kivel, N; Koehler, P; Kokkoris, M; Korschinek, G; Krtička, M; Kroll, J; Langer, C; Lederer, C; Leeb, H; Leong, L S; Losito, R; Manousos, A; Marganiec, J; Martínez, T; Mastinu, P F; Mastromarco, M; Massimi, C; Meaze, M; Mendoza, E; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondelaers, W; Paradela, C; Pavlik, A; Perkowski, J; Pignatari, M; Plompen, A; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Roman, F; Rubbia, C; Sarmento, R; Schillebeeckx, P; Schmidt, S; Schumann, D; Tagliente, G; Tain, J L; Tarrío, D; Tassan-Got, L; Tsinganis, A; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Versaci, R; Vermeulen, M J; Vlachoudis, V; Vlastou, R; Wallner, A; Ware, T; Weigand, M; Weiß, C; Wright, T J; Žugec, P

    2014-01-01

    The neutron time-of-flight facility n\\_TOF is operating at CERN (Switzerland) since 2001, having started in 2009 a new campaign with an upgraded spallation target. The ambitious program carried out includes a large number of experiments in nuclear technology, astrophysics, basic physics, detector development and medical applications. This paper is devoted to the physics program at n\\_TOF and the measurements performed between 2009 and 2012. Special attention is given to those experiments that have been most challenging, are more important for a particular field, have reached unprecedented levels of accuracy, or have been carried out for the first time ever.

  9. A retrospective investigation on canine papillomavirus 1 (CPV1 in oral oncogenesis reveals dogs are not a suitable animal model for high-risk HPV-induced oral cancer.

    Directory of Open Access Journals (Sweden)

    Ilaria Porcellato

    Full Text Available CPV1 (also called COPV is a papillomavirus responsible for oral papillomatosis in young dogs. The involvement of this viral type in oral oncogenesis has been hypothesized in oral squamous cell carcinomas (SCCs, but has never been investigated in other neoplastic and hyperplastic oral lesions of dogs. Aim of this study was to investigate the presence of CPV1 in different neoplastic and hyperplastic lesions in order to assess its role in canine oral oncogenesis; according to the results obtained, a second aim of the study was to define if the dog can be considered a valid animal model for oral high risk HPV-induced tumors. Eighty-eight formalin-fixed, paraffin-embedded (FFPE canine oral lesions including 78 oral tumors (papillomas, SCCs, melanomas, ameloblastomas, oral adenocarcinomas and 10 hyperplastic lesions (gingival hyperplasia were investigated with immunohistochemistry for the presence of papillomavirus L1 protein and with Real-Time PCR for CPV1 DNA. RT-PCR for RNA was performed on selected samples. All viral papillomas tested were positive for immunohistochemistry and Real-time PCR. In 3/33 (10% SCCs, viral DNA was demonstrated but no viral RNA could be found. No positivity was observed both with immunohistochemistry and Real-Time PCR in the other hyperplastic and neoplastic lesions of the oral cavity of dogs. Even though the finding of CPV1 DNA in few SCCs in face of a negative immunohistochemistry could support the hypothesis of an abortive infection in the development of these lesions, the absence of viral RNA points out that CPV1 more likely represents an innocent bystander in SCC oncogenesis. The study demonstrates a strong association between CPV1 and oral viral papillomas whereas viral contribution to the pathogenesis of other oral lesions seems unlikely. Moreover, it suggests that a canine model of CPV1 infection for HPV-induced oncogenesis could be inappropriate.

  10. Establishment for quality control of experimental animal

    International Nuclear Information System (INIS)

    Until now, because we have imported experimental animal from foreign experimental animal corporation, we could have saved money by establishing the quality control of animal in barrier system. In order to improve the quality of animal experiment and efficiency of biomedical study, it is indispensable to control many factors that effect in the experiment. Therefore, it is essential to organize the system of laboratory animal care for enhancing reliability and revivability of experimental results. The purpose of the present investigation was to establish the quality control system of experimental animals that we can provide good quality animals according to the experimental condition of each investigator although the exact quality control system to estimate the infection of bacteria and virus easily remains ill-defined yet. Accordingly, we established the useful quality control system for microbiologic monitoring and environmental monitoring to protect experimental animal from harmful bacteria and virus

  11. Establishment for quality control of experimental animal

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Hwan; Kim, Soo Kwan; Kim, Tae Kyoung

    1999-06-01

    Until now, because we have imported experimental animal from foreign experimental animal corporation, we could have saved money by establishing the quality control of animal in barrier system. In order to improve the quality of animal experiment and efficiency of biomedical study, it is indispensable to control many factors that effect in the experiment. Therefore, it is essential to organize the system of laboratory animal care for enhancing reliability and revivability of experimental results. The purpose of the present investigation was to establish the quality control system of experimental animals that we can provide good quality animals according to the experimental condition of each investigator although the exact quality control system to estimate the infection of bacteria and virus easily remains ill-defined yet. Accordingly, we established the useful quality control system for microbiologic monitoring and environmental monitoring to protect experimental animal from harmful bacteria and virus.

  12. Pursuing an understanding of animal consciousness: Implications for animal morality and a creaturely theology

    OpenAIRE

    Cornel W. du Toit

    2015-01-01

    The importance of animals in the evolutionary history of homo sapiens comes to the fore in light of an increasingly trans-human techno-scientific environment. New research on consciousness, and animal consciousness in particular, has prompted questions relating to animal rights, animal morality and the emergence of a creaturely theology and theological primatology. The possibility of understanding nonhuman animals is investigated with reference to notions like consciousness, thinking, awarene...

  13. The methods of inducing polymyositis animal model

    International Nuclear Information System (INIS)

    Objective: To investigate the methods of inducing polymyosistis(PM) animal model. Methods: In order to develope a induce PM animal model in purified guinea pia muscle myosin mixed with complete Freund adjuvant was injected subcutaneously to SD rats many times and the results of the clinical finding, the EMG, the pathologic changes and the musclar MRI changes in SD rats was assessed. Results: The PM animal models were similar to the human in clinical findings, the EMG, the pathologic changes, the musclar MRI changes and so on. Conclusion: The animal model is similar to the human PM, it is an ideal animal model to investigate PM. (authors)

  14. An Exploratory Study to Investigate the Impact of an Enrichment Program on Aspects of Einsteinian Physics on Year 6 Students

    Science.gov (United States)

    Pitts, Marina; Venville, Grady; Blair, David; Zadnik, Marjan

    2014-06-01

    Concepts related to Einsteinian physics are usually not taught until students are in university, denying younger children access to this powerful way of understanding space, time and gravity. Considerable research has shown, however, that complex and abstract scientific ideas can be presented in age appropriate ways that result in measurable learning. The purpose of the research presented in this paper was to explore the impact of an enrichment program on aspects of Einsteinian physics on year 6 (10 and 11 years old) children's understanding of and attitudes towards this topic. The research design was an exploratory case study of one class of 26 students who participated in six in-class lessons as well as an excursion to a science centre, the Gravity Discovery Centre, and a scripted play about relevant key scientists. Mixed methods of data collection included a pre/post-instruction questionnaire, classroom observations and an interview with the physics professor who conducted the program. The results indicated a statistically significant improvement in children's conceptual understanding on the pre/post-questionnaire with a small effect size. Analysis of individual items on the questionnaire indicated variable results with regard to particular concepts. For example, after the enrichment program, students were better able to understand curved space, but little improvement was observed in their understanding of gravity on the Moon. The majority of students reported being interested and engaged in the program of activities and did not feel that they were too young to learn concepts related to Einstein's physics.

  15. Behind the Curtain of the Beauty Pageant: An Investigation of U.S. News Undergraduate Business Program Rankings

    Science.gov (United States)

    Perry, Pam

    2010-01-01

    The undergraduate business program rankings in USNWR are based solely on peer assessments from deans and associate deans of AACSB accredited U.S. business schools. Often these reputation-based rankings are discounted and likened to a beauty pageant because the process lacks transparent input data. In this study, ten deans and ten associate…

  16. An Investigation of the Potential for a Computer-based Tutorial Program Covering the Cardiovascular System to Replace Traditional Lectures.

    Science.gov (United States)

    Dewhurst, D. G.; Williams, A. D.

    1998-01-01

    Presents the results of a comparative study to evaluate the effectiveness of two interactive computer-based learning (CBL) programs, covering the cardiovascular system, as an alternative to lectures for first year undergraduate students at a United Kingdom University. Discusses results in relation to the design of evaluative studies and the future…

  17. Analytic investigation of efficiency and performance limits in klystron amplifiers using multidimensional computer programs; multi-stage depressed collectors; and thermionic cathode life studies

    Science.gov (United States)

    Kosmahl, H. G.

    1980-01-01

    Due to complexity of the program which used a hydrodynamic, axially and radially deformable disk-ring model and the resulting long computing time only the output gap was investigated. Results from independent studies were used to initiate the starting conditions for the electrons and the RF voltage using our program. Although this method of computation is less exact than processing the entire klystron interaction in 3-Dimensions it is shown that, for a confined flow focused throughout the penultimate cavity, radial velocities remain very small and the beam is highly laminar. It is concluded that possible errors resulting from treating only the output cavity in 3-D would remain small.

  18. Evaluation of animal models of neurobehavioral disorders

    OpenAIRE

    Nordquist Rebecca E; Arndt Saskia S; van der Staay F Josef

    2009-01-01

    Abstract Animal models play a central role in all areas of biomedical research. The process of animal model building, development and evaluation has rarely been addressed systematically, despite the long history of using animal models in the investigation of neuropsychiatric disorders and behavioral dysfunctions. An iterative, multi-stage trajectory for developing animal models and assessing their quality is proposed. The process starts with defining the purpose(s) of the model, preferentiall...

  19. Seeing the animal

    DEFF Research Database (Denmark)

    Harfeld, Jes Lynning; Cornou, Cecile; Kornum, Anna;

    2016-01-01

    This article discusses the notion that the invisibility of the animalness of the animal constitutes a fundamental obstacle to change within current production systems. It is discussed whether housing animals in environments that resemble natural habitats could lead to a re-animalization...... of the animals, a higher appreciation of their moral significance, and thereby higher standards of animal welfare. The basic claim is that experiencing the animals in their evolutionary and environmental context would make it harder to objectify animals as mere bioreactors and production systems. It is argued...... that the historic objectification of animals within intensive animal production can only be reversed if animals are given the chance to express themselves as they are and not as we see them through the tunnel visions of economy and quantifiable welfare assessment parameters....

  20. Animal rights, animal minds, and human mindreading.

    Science.gov (United States)

    Mameli, M; Bortolotti, L

    2006-02-01

    Do non-human animals have rights? The answer to this question depends on whether animals have morally relevant mental properties. Mindreading is the human activity of ascribing mental states to other organisms. Current knowledge about the evolution and cognitive structure of mindreading indicates that human ascriptions of mental states to non-human animals are very inaccurate. The accuracy of human mindreading can be improved with the help of scientific studies of animal minds. However, the scientific studies do not by themselves solve the problem of how to map psychological similarities (and differences) between humans and animals onto a distinction between morally relevant and morally irrelevant mental properties. The current limitations of human mindreading-whether scientifically aided or not-have practical consequences for the rational justification of claims about which rights (if any) non-human animals should be accorded.

  1. Refining Animal Models to Enhance Animal Welfare

    Institute of Scientific and Technical Information of China (English)

    Patricia V.Turner

    2012-01-01

    The use of animals in research will be necessary for scientific advances in the basic and biomedical sciences for the foreseeable future.As we learn more about the ability of animals to experience pain,suffering,and distress,and particularly for mammals,it becomes the responsibility of scientists,institutions,animal caregivers,and veterinarians to seek ways to improve the lives of research animals and refine their care and use.Refinement is one of the three R's emphasized by Russell and Burch,and refers to modification of procedures to minimise the potential for pain,suffering and distress. It may also refer to procedures used to enhance animal comfort. This paper summarizes considerations for refinements in research animal.

  2. Improvement in the occupational health program in a Finnish construction company by means of systematic workplace investigation of job load and hazard analysis.

    Science.gov (United States)

    Mattila, M

    1989-01-01

    The aim of the present study was to improve an occupational health program by means of systematic workplace investigations. The 8-month study was done at three building sites of one construction firm. The method for workplace investigations was a simple job hazard analysis of chemical hazards, physical hazards, physical work load, mental stress, and risk of injury, each factor being rated on a three-point scale. Information was gathered by observations, interviews, and a worker questionnaire. Occupational health and safety personnel and worker representatives dealt with problems cooperatively. Together they assessed occupational loads and hazards, whereafter the occupational health and safety personnel devised an occupational health care program and proposed preventive measures. The workplace investigation method proved to function well. It improved the occupational health care program, produced an overall analysis of occupational hazards, and dramatically increased the number and quality of proposed preventive measures. The new method was evaluated to be clearly superior to previous practices and was implemented at moderate cost. The study showed that attention to issues of environmental and occupational health can effectively prevent health impairment even in difficult setting such as construction work. More research is needed for effective utilization of information accumulated by systematic workplace investigations. PMID:2929609

  3. Separation of haemopoietic cells for biochemical investigation. Preparation of erythroid and myeloid cells from human and laboratory-animal bone marrow and the separation of erythroblasts according to their state of maturation.

    Science.gov (United States)

    Harrison, F L; Beswick, T M; Chesterton, C J

    1981-03-15

    The separation of haemopoietic bone-marrow cells by centrifugation through discontinuous density gradients of Percoll is described. This method was used to prepare fractions enriched in erythroblasts, myeloid blast cells or reticulocytes from bone marrow of anaemic and non-anaemic rabbits, from the marrow of other anaemic laboratory animals and from human samples. It is a simple, rapid, reproducible and inexpensive technique that can be readily adapted to suit individual requirements. Secondly, a convenient method is presented for the separation of large quantities of bone-marrow cells into fractions enriched in erythroblasts at different stages of maturation, by velocity sedimentation through a linear gradient of 1-2% sucrose at unit gravity. In vitro, erythroblasts adhere together strongly via a mechanism almost certainly involving a beta-galactoside-specific surface lectin termed erythroid developmental agglutinin. Since the efficiency of cell-separation techniques depends heavily on the maintenance of a single cell suspension in which each unit can move independently, the presence of an adhesive molecule at the cell surface is of considerable significance. The effect of washing the marrow with a lactose-containing medium, which has been shown to remove the agglutinin, was therefore investigated in relation to both methods. The separation on Percoll gradients is considerably enhanced by this treatment. In addition, the unit-gravity sedimentation gradient can be loaded with 5-10 times more cells after lactose extraction in comparison with intact marrow. Although enrichment is less, a useful fractionation according to maturation is still obtained.

  4. Animal Images and Metaphors in Animal Farm

    OpenAIRE

    Ping Sun

    2015-01-01

    In literary works animal images are frequently used as the “source domain” of a metaphor to disclose the natures of the “target domain”, human beings. This is called “cross-domain mapping” or “conceptual metaphor” in cognitive linguistics, which is based on the similar qualities between animals and human beings. Thus the apparent descriptions of the animals are really the deep revelations of the human beings. Animal Farm is one exemplary product of this special expressing way. Diversified ani...

  5. Investigation of the applicability of a functional programming model to fault-tolerant parallel processing for knowledge-based systems

    Science.gov (United States)

    Harper, Richard

    1989-01-01

    In a fault-tolerant parallel computer, a functional programming model can facilitate distributed checkpointing, error recovery, load balancing, and graceful degradation. Such a model has been implemented on the Draper Fault-Tolerant Parallel Processor (FTPP). When used in conjunction with the FTPP's fault detection and masking capabilities, this implementation results in a graceful degradation of system performance after faults. Three graceful degradation algorithms have been implemented and are presented. A user interface has been implemented which requires minimal cognitive overhead by the application programmer, masking such complexities as the system's redundancy, distributed nature, variable complement of processing resources, load balancing, fault occurrence and recovery. This user interface is described and its use demonstrated. The applicability of the functional programming style to the Activation Framework, a paradigm for intelligent systems, is then briefly described.

  6. 75 FR 24569 - Animal Traceability; Public Meetings

    Science.gov (United States)

    2010-05-05

    ... CONTACT: Mr. Neil Hammerschmidt, Program Manager, Animal Disease Traceability, VS, APHIS, 4700 River Road... distance. For the Denver meeting, there will be a free hotel shuttle to and from Denver...

  7. Animal production and health newsletter. No. 26

    International Nuclear Information System (INIS)

    This issue of the newsletter highlights coordinated research programs in animal diseases including ELISA and RIA techniques in reproductive studies. Announcement of staff changes and forthcoming events are also covered

  8. Subseabed disposal program annual report, January-December 1980. Volume II. Appendices (principal investigator progress reports). Part 1

    Energy Technology Data Exchange (ETDEWEB)

    Hinga, K.R. (ed.)

    1981-07-01

    Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-Q; Part 2 contains Appendices R-MM. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base.

  9. Subseabed disposal program annual report, January-December 1979. Volume II. Appendices (principal investigator progress reports). Part 1 of 2

    International Nuclear Information System (INIS)

    Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-O; Part 2 contains Appendices P-FF. Separate abstracts have been prepared of each Appendix for inclusion in the Energy Data Base

  10. Subseabed disposal program annual report, January-December 1980. Volume II. Appendices (principal investigator progress reports). Part 1

    International Nuclear Information System (INIS)

    Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-Q; Part 2 contains Appendices R-MM. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base

  11. INVESTIGATION OF STUDENTS’ INTENTION FOR POSSIBLE PARTICIPATION IN A “MUSIC AND DANCE” DISTANCE EDUCATION MASTER PROGRAM

    OpenAIRE

    Dimitrios GOULIMARIS

    2015-01-01

    The study uses the “theory of planned behavior” as a theoretical framework. The aim of this research is to ascertain if the demographic characteristics of students differentiate the factors of “planned behavior theory” concerning students’ participation in a music and dance distance education master program. The sample consisted of 96 University undergraduate students with Major in Physical Education and Minor in Dance Studies, between the ages of 20-22. Planned behavior was assessed using th...

  12. Subseabed disposal program annual report, January-December 1979. Volume II. Appendices (principal investigator progress reports). Part 2 of 2

    International Nuclear Information System (INIS)

    Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume II, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-O; Part 2 contains Appendices P-FF. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base

  13. Development of a computer program to investigate electrical properties of Phuket pineapple leaf single cells by using dielectrophoresis

    Directory of Open Access Journals (Sweden)

    Boonlamp, M.

    2003-05-01

    Full Text Available This research developed a computer program to calculate electrical properties of a cell from a spherical single shell model. The program compared the results between the theoretical values (Re[f(ω]TDS and the experimental values (Re[f(ω]EDS. The latter was computed from a cell velocity obtained from dielectrophoresis. The calculation was repeated until the error percentile was in a proper range. The program was applied to process the electrical properties of Phuket pineapple protoplasts [Ananas comosus (L. Merr.C.V. Phuket]. It was found that the thickness of the cell membrane was 10 nm, the dielectric constants of suspending solution, cytoplasm and cell membrane were 80ε0, 58-60ε0 and 10-14ε0 respectively (ε0 is the dielectric constant of the vacuum = 8.85×10-12 F m-1. The conductivity of cytoplasm and cell membrane were 0.09 S m-1 and 10-5 - 10-4 S m-1 respectively.

  14. Ian Ingram: Next Animals

    DEFF Research Database (Denmark)

    2015-01-01

    Ian Ingram: Next Animals is an exhibition catalogue presenting research on the work by Ian Ingram in relation to his exhibition Next Animals at Nikolaj Kunsthal in 2015.......Ian Ingram: Next Animals is an exhibition catalogue presenting research on the work by Ian Ingram in relation to his exhibition Next Animals at Nikolaj Kunsthal in 2015....

  15. FARM ANIMAL WELFARE ECONOMICS

    Directory of Open Access Journals (Sweden)

    L.T. CZISZTER

    2013-07-01

    Full Text Available This paper reviews the literature regarding the economics of the farm animal welfare. The following issues are addressed: productions costs and savings of the animal welfare regulations, benefits of improved animal welfare, and consumers’ willingness to pay for animal-friendly products.

  16. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... En Español Search FDA Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, ... Biologics Animal & Veterinary Cosmetics Tobacco Products Animal & Veterinary Home Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of ...

  17. An investigation of a coincidence detection system for an all-digital small animal PET scanner%全数字化小动物PET符合探测系统的设计与研究

    Institute of Scientific and Technical Information of China (English)

    刘伟; 陈源宝; 龙岸文; 陈忻; 吴中毅; 张永学; 谢庆国

    2013-01-01

    Objective To investigate and design a coincidence detection system for an all-digital small animal PET scanner and evaluate its preliminary performance properties.Methods This coincidence module adopted a coincidence identification mode based on singles data in list-mode.Using digital signal processing technology,energy calibration,crystal identification,timing alignment and coincidence events extraction were performed on singles data in list-mode.The obtained data could be used for image reconstruction.Results The 13 × 13 crystal array was well recognized by the position histogram of one lutetium yttrium orthosilicate (LYSO) crystal block.In the coincidence timing histogram of the micro-Derenzo phantom,1.36 ns full width at half maximum was obtained.The rods with a diameter of 1.2 mm were clearly displayed in the reconstructed image of the micro-Derenzo phantom.Conclusion The coincidence module can provide satisfactory performance to meet the design needs of an all-digital small animal PET scanner.%目的 设计和研究全数字化小动物PET符合探测系统,并对其进行初步性能评估.方法 采用基于单事件列表式数据的符合判选模式,运用数字信号处理技术对单事件数据集进行晶格分割、能量校正、时间校正以及符合事件判断等操作,获取可供图像重建使用的数据.结果 硅酸钇镥闪烁晶体(LYSO)晶体阵列点阵图可清晰分辨13×13个晶格点.Micro-Derenzo假体符合时间分布图的半高全宽为1.36 ns.Micro-Derenzo假体重建图像可清晰分辨直径为1.2 mm的小孔.结论 硬件软件化的符合探测模式可以提供满意的性能指标,满足全数字化小动物PET的设计需求.

  18. Carotenoids in Marine Animals

    Directory of Open Access Journals (Sweden)

    Takashi Maoka

    2011-02-01

    Full Text Available Marine animals contain various carotenoids that show structural diversity. These marine animals accumulate carotenoids from foods such as algae and other animals and modify them through metabolic reactions. Many of the carotenoids present in marine animals are metabolites of β-carotene, fucoxanthin, peridinin, diatoxanthin, alloxanthin, and astaxanthin, etc. Carotenoids found in these animals provide the food chain as well as metabolic pathways. In the present review, I will describe marine animal carotenoids from natural product chemistry, metabolism, food chain, and chemosystematic viewpoints, and also describe new structural carotenoids isolated from marine animals over the last decade.

  19. SERI Biomass Program

    Science.gov (United States)

    Bergeron, P. W.; Corder, R. E.; Hill, A. M.; Lindsey, H.; Lowenstein, M. Z.

    1983-02-01

    The biomass with which this report is concerned includes aquatic plants, which can be converted into liquid fuels and chemicals; organic wastes (crop residues as well as animal and municipal wastes), from which biogas can be produced via anerobic digestion; and organic or inorganic waste streams, from which hydrogen can be produced by photobiological processes. The Biomass Program Office supports research in three areas which, although distinct, all use living organisms to create the desired products. The Aquatic Species Program (ASP) supports research on organisms that are themselves processed into the final products, while the Anaerobic Digestion (ADP) and Photo/Biological Hydrogen Program (P/BHP) deals with organisms that transform waste streams into energy products. The P/BHP is also investigating systems using water as a feedstock and cell-free systems which do not utilize living organisms. This report summarizes the progress and research accomplishments of the SERI Biomass Program during FY 1982.

  20. Animal studies of addictive behavior.

    Science.gov (United States)

    Vanderschuren, Louk J M J; Ahmed, Serge H

    2013-04-01

    It is increasingly recognized that studying drug taking in laboratory animals does not equate to studying genuine addiction, characterized by loss of control over drug use. This has inspired recent work aimed at capturing genuine addiction-like behavior in animals. In this work, we summarize empirical evidence for the occurrence of several DSM-IV-like symptoms of addiction in animals after extended drug use. These symptoms include escalation of drug use, neurocognitive deficits, resistance to extinction, increased motivation for drugs, preference for drugs over nondrug rewards, and resistance to punishment. The fact that addiction-like behavior can occur and be studied in animals gives us the exciting opportunity to investigate the neural and genetic background of drug addiction, which we hope will ultimately lead to the development of more effective treatments for this devastating disorder.

  1. Animal studies of addictive behavior.

    Science.gov (United States)

    Vanderschuren, Louk J M J; Ahmed, Serge H

    2013-04-01

    It is increasingly recognized that studying drug taking in laboratory animals does not equate to studying genuine addiction, characterized by loss of control over drug use. This has inspired recent work aimed at capturing genuine addiction-like behavior in animals. In this work, we summarize empirical evidence for the occurrence of several DSM-IV-like symptoms of addiction in animals after extended drug use. These symptoms include escalation of drug use, neurocognitive deficits, resistance to extinction, increased motivation for drugs, preference for drugs over nondrug rewards, and resistance to punishment. The fact that addiction-like behavior can occur and be studied in animals gives us the exciting opportunity to investigate the neural and genetic background of drug addiction, which we hope will ultimately lead to the development of more effective treatments for this devastating disorder. PMID:23249442

  2. Ethics in Animal Experimentation

    Directory of Open Access Journals (Sweden)

    Yusuf Ergun

    2010-08-01

    Full Text Available Experimental animals are frequently used to obtain information for primarily scientific reasons. In the present review, ethics in animal experimentation is examined. At first, the history of animal experimentation and animal rights is outlined. Thereafter, the terms in relation with the topic are defined. Finally, prominent aspects of 3Rs constituting scientific and ethical basis in animal experimentation are underlined. [Archives Medical Review Journal 2010; 19(4.000: 220-235

  3. Ethics in Animal Experimentation

    OpenAIRE

    Yusuf Ergun

    2010-01-01

    Experimental animals are frequently used to obtain information for primarily scientific reasons. In the present review, ethics in animal experimentation is examined. At first, the history of animal experimentation and animal rights is outlined. Thereafter, the terms in relation with the topic are defined. Finally, prominent aspects of 3Rs constituting scientific and ethical basis in animal experimentation are underlined. [Archives Medical Review Journal 2010; 19(4.000): 220-235

  4. Carotenoids in Marine Animals

    OpenAIRE

    Takashi Maoka

    2011-01-01

    Marine animals contain various carotenoids that show structural diversity. These marine animals accumulate carotenoids from foods such as algae and other animals and modify them through metabolic reactions. Many of the carotenoids present in marine animals are metabolites of β-carotene, fucoxanthin, peridinin, diatoxanthin, alloxanthin, and astaxanthin, etc. Carotenoids found in these animals provide the food chain as well as metabolic pathways. In the present review, I will describe marine a...

  5. Using ComBase Predictor and Pathogen Modeling Program as support tools in outbreak investigation: an example from Denmark

    DEFF Research Database (Denmark)

    Møller, Cleide; Hansen, Tina Beck; Andersen, Jens Kirk

    , or even multiplied, during the production of the suspected sausage?” To elucidate this, the ComBase Predictor (CBP) and the Pathogen Modeling Program (PMP) were used as support tools. From information on the company’s website, it was calculated that the water phase salt changed from 4.6% to 8.0% during....... The results showed that Y. enterocolitica would be able to multiply during the first part of the production. Compared to E. coli growth of Y. enterocolitica was predicted to be slower in the beginning of the fermentation but faster in the end with CBP and faster during the whole fermentation with PMP. CBP...

  6. Using ComBase Predictor and Pathogen Modeling Program as support tools in outbreak investigation: an example from Denmark

    DEFF Research Database (Denmark)

    Møller, Cleide; Hansen, Tina Beck; Andersen, Jens Kirk

    2009-01-01

    , or even multiplied, during the production of the suspected sausage?” To elucidate this, the ComBase Predictor (CBP) and the Pathogen Modeling Program (PMP) were used as support tools. From information on the company’s website, it was calculated that the water phase salt changed from 4.6% to 8.0% during....... The results showed that Y. enterocolitica would be able to multiply during the first part of the production. Compared to E. coli growth of Y. enterocolitica was predicted to be slower in the beginning of the fermentation but faster in the end with CBP and faster during the whole fermentation with PMP. CBP...

  7. Progress report on the scientific investigation program for the Nevada Yucca Mountain site, September 15, 1988--September 30, 1989

    International Nuclear Information System (INIS)

    The Department of Energy (DOE) has prepared this report on the progress of site characterization activities at Yucca Mountain in southern Nevada. This report is the first of a series of reports that will hereafter be issued at intervals of approximately 6-months during site characterization. The DOE's plans for site characterization are described in the Site Characterization Plan (SCP) for the Yucca Mountain site. The SCP has been reviewed and commented on by the NRC, the State of Nevada, the affected units of local government, other interested parties, and the public. More detailed information on plans for site characterization is being presented in study plans for the various site characterization activities. This progress report presents short summaries of the status of site characterization activities and cites technical reports and research products that provide more detailed information on the activities. The report provides highlights of work started during the reporting period, work in progress, and work completed and documented during the reporting period. In addition, the report is the vehicle for discussing major changes, if any, to the DOE's site characterization program resulting from ongoing collection and evaluation of site information; the development of repository and waste-package designs; receipt of performance-assessment results; and changes, if any, that occur in response to external comments on the site characterization programs. 80 refs

  8. Laboratory Animal Models for Brucellosis Research

    Directory of Open Access Journals (Sweden)

    Teane M. A. Silva

    2011-01-01

    Full Text Available Brucellosis is a chronic infectious disease caused by Brucella spp., a Gram-negative facultative intracellular pathogen that affects humans and animals, leading to significant impact on public health and animal industry. Human brucellosis is considered the most prevalent bacterial zoonosis in the world and is characterized by fever, weight loss, depression, hepato/splenomegaly, osteoarticular, and genital infections. Relevant aspects of Brucella pathogenesis have been intensively investigated in culture cells and animal models. The mouse is the animal model more commonly used to study chronic infection caused by Brucella. This model is most frequently used to investigate specific pathogenic factors of Brucella spp., to characterize the host immune response, and to evaluate therapeutics and vaccines. Other animal species have been used as models for brucellosis including rats, guinea pigs, and monkeys. This paper discusses the murine and other laboratory animal models for human and animal brucellosis.

  9. Enhancing animal welfare by creating opportunities for positive affective engagement.

    Science.gov (United States)

    Mellor, D J

    2015-01-01

    of sexual activity. It is argued that highlighting the genetically pre-programmed, affectively positive impulses to engage in reward-motivated activities such as these, and the positive affects that may attend different facets of the process, draws attention to a wider spectrum of welfare enhancing experiences than has hitherto been considered to be important to animals. These neuroscience-supported observations strengthen many prior inferences made from predominantly behaviour-based investigations of animals' preferences, aversions and priorities, the associated development of successful environmental enrichments and the inclusion of these, where practicable, in more recent codes of practice or welfare. PMID:24875268

  10. The Aristocrat of Bands: A Historical Investigation of the Tennessee State University Instrumental Music Program and Its Directors

    Science.gov (United States)

    McDonald, Reginald A.

    2009-01-01

    Instrumental music education, as it evolved in the segregated African American communities and their educational institutions, remains an under-investigated area of historical research. As a partial remedy to that circumstance, this study sought to document one of the more noteworthy of such accounts, the history of instrumental music ensembles at…

  11. Readying One's Self: A Grounded Theory Investigation of the LatinoJustice PRLDEF LawBound Program Participants

    Science.gov (United States)

    Joseph, Angela Marie Banner

    2011-01-01

    This study was a grounded theory investigation of the LatinoJustice PRLDEF LawBound participants. The research was conducted using the grounded theory method developed by Glaser and Strauss (1967) and Glaser (1978, 1992, 1993, 1996, 1998, 2001, 2003, 2005) to discover an explanatory theory directly from the data. The discovery of the…

  12. Are They Ready to Teach with Technology? An Investigation of Technology Instruction in Music Teacher Education Programs

    Science.gov (United States)

    Haning, Marshall

    2016-01-01

    The purpose of this research was to investigate the type, quantity, and effects of technology instruction currently being provided to undergraduate music education majors. Undergraduate participants (n = 46) at 10 degree-granting institutions completed an online survey on the technology instruction received during their undergraduate degree…

  13. Investigation on animal natural infection of Orientia tsutsugamushi in some areas of Bole area in Xinjiang,China%新疆博乐地区动物感染恙虫病东方体调查研究

    Institute of Scientific and Technical Information of China (English)

    党荣理; 任立松; 高金拽; 马德新; 董路宁

    2011-01-01

    Objective To investigate animal natural infection of Orientia tsutsugamushi (Ot) in Bole area of Xinjiang, China. Methods Internal jugular vein puncture was used to collect blood and extract DNA from spleens of the captured mice, nested-polymerase chain reaction (nPCR) technique was used to detect the Ot-Sta 56 gene Some positive samples were sequenced and analyzed in BLAST through NCBI website. Results A total of 154 rodents, 12 birds and 26 woodchucks were captured in Bole district, Xinjiang uyghur Autonomous Region. The positive samples were observed in the rodents, birds and sheep in the steppe and plain. The prevalence rates of Ot were 5. 56%, 3. 81% and 16. 67% in the three animals respectively. The Sta56 gene nucleotide sequence similarity of Karp strain was 97 %. Conclusion The results indicated that infections of Ot existed in rodents, birds and sheep lived in plain and everglade of Bole district. It could provide scientific basis for further investigation on the epidemic focus of scrub typhus in this area.%目的 了解新疆博乐地区动物自然感染恙虫病东方体(Ot)的情况.方法 捕鼠、旱獭取脾组织,采用颈部静脉刺穿法取羊血,提取DNA,应用巢式PCR(nPCR)检测Ot-Sta56基因;对部分阳性样本测序,通过NCBI网站对序列进行BLAST比较分析.结果 在博乐地区平原湿地、农田和居民区捕鼠126只,其中7只nPCR检测阳性,阳性率5.56%;取绵羊群血210份,8份nPCR检测阳性,阳性率为3.81%;捕获鸟类12只,其中2只nPCR检测阳性,阳性率为16.67%.在山地草原捕获鼠58只,捕获旱獭26只,nPCR检测无阳性.DNA序列分析表明,鼠类、鸟类、羊血阳性样本nPCR产物碱基序列相同,与Karp株相应DNA片段的碱基序列同源性最高,均为97%,应属于Karp型.结论 在新疆博乐地区平原湿地中存在恙虫病东方体感染,为下一步深入进行该地区恙虫病东方体疫源地的调查奠定了基础.

  14. Epidemiology and investigation of Echinococcus infection in domestic animal in six counties, Xinjiang area%新疆地区6县棘球蚴病流行病学调查

    Institute of Scientific and Technical Information of China (English)

    马力克·艾则孜

    2012-01-01

    :In order to study the; prevalence situation of Echinococcus granulosus in cattle , sheep , and dog in Xinjiang area, the infection of hydatidosis in animal in 6 different districts of Xinjiang was surveyed from March to November in 2010 . Echinococcus granulosus in the livers and lungs of cattle and sheep were detected directly in the slaughterhouse . Dogs' feces were detected by enzyme-linked immnnoabsorbent assay . It was found that the numbers of detected samples were 604 (sheep) , 582 (cattle) and 1 080 (dog) , respectively . The infection rate was 45 .58% (sheep) , 20 .83% (cattle;) and 17% (dog) , respectively . The investigation results suggest that the Echinococcus granulosus is widespread and high in infection rates in Xinjiang .%目的 为掌握新疆地区家畜棘球蚴病的流行病学情况,2010年4月至2010年11月对其6个县进行了牛、羊、犬包虫感染情况调查.方法 通过在屠宰场直接检查牛、羊肝脏和肺脏的棘球蚴数量,采用酶联免疫吸附试验方法检测犬的粪便.结果 共检查羊604只,感染率为45.58%;共检查牛582头,感染率为20.83%;共检测1 080只犬的粪样,虫体阳性率为17%.结论 棘球蚴病在新疆的家畜中流行广泛、感染率高,应引起高度重视.

  15. Progress report No. 2 on the Scientific Investigation Program for the Nevada Yucca Mountain Site, October 1, 1989--March 31, 1990

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-12-31

    In accordance with the requirements of Section 113(b)(3) of the Nuclear Waste Policy Act of 1982 (Pub. L. No. 97-425), as amended, the US Department of Energy (DOE) has prepared this report on the progress of scientific investigation activities at Yucca Mountain in southern Nevada for October 1, 1989, through March 31, 1990. This report is the second of a series of reports that are issued at intervals of approximately six months during the period of scientific investigation. The progress report presents short summaries of the status of scientific investigation activities and cites technical reports and research products that provide more detailed information on the activities. The report provides highlights of work started during the reporting period, work in progress, and work completed and documented during the reporting period. In addition, the report is the vehicle for discussing major changes, if any, to the DOE`s scientific investigation program. The progress report conveys information in a convenient summary form to be used for informational purposes only. It is not intended to be the mechanism for controlling and documenting technical or policy positions regarding changes in schedules or the technical program. Such changes are controlled through rigorous DOE change-control procedures. The progress report only describes such approval changes. 49 refs., 3 tabs.

  16. Progress report No. 2 on the Scientific Investigation Program for the Nevada Yucca Mountain Site, October 1, 1989--March 31, 1990

    International Nuclear Information System (INIS)

    In accordance with the requirements of Section 113(b)(3) of the Nuclear Waste Policy Act of 1982 (Pub. L. No. 97-425), as amended, the US Department of Energy (DOE) has prepared this report on the progress of scientific investigation activities at Yucca Mountain in southern Nevada for October 1, 1989, through March 31, 1990. This report is the second of a series of reports that are issued at intervals of approximately six months during the period of scientific investigation. The progress report presents short summaries of the status of scientific investigation activities and cites technical reports and research products that provide more detailed information on the activities. The report provides highlights of work started during the reporting period, work in progress, and work completed and documented during the reporting period. In addition, the report is the vehicle for discussing major changes, if any, to the DOE's scientific investigation program. The progress report conveys information in a convenient summary form to be used for informational purposes only. It is not intended to be the mechanism for controlling and documenting technical or policy positions regarding changes in schedules or the technical program. Such changes are controlled through rigorous DOE change-control procedures. The progress report only describes such approval changes. 49 refs., 3 tabs

  17. Animal models for human diseases.

    Science.gov (United States)

    Rust, J H

    1982-01-01

    The use of animal models for the study of human disease is, for the most part, a recent development. This discussion of the use of animal models for human diseases directs attention to the sterile period, early advances, some personal experiences, the human as the model, biological oddities among common laboratory animals, malignancies in laboratory animals, problems created by federal regulations, cancer tests with animals, and what the future holds in terms of the use of animal models as an aid to understanding human disease. In terms of early use of animal models, there was a school of rabbis, some of whom were also physicians, in Babylon who studied and wrote extensively on ritual slaughter and the suitability of birds and beasts for food. Considerable detailed information on animal pathology, physiology, anatomy, and medicine in general can be found in the Soncino Babylonian Talmudic Translations. The 1906 edition of the "Jewish Encyclopedia," has been a rich resource. Although it has not been possible to establish what diseases of animals were studied and their relationship to the diseases of humans, there are fascinating clues to pursue, despite the fact that these were sterile years for research in medicine. The quotation from the Talmud is of interest: "The medical knowledge of the Talmudist was based upon tradition, the dissection of human bodies, observation of disease and experiments upon animals." A bright light in the lackluster years of medical research was provided by Galen, considered the originator of research in physiology and anatomy. His dissection of animals and work on apes and other lower animals were models for human anatomy and physiology and the bases for many treatises. Yet, Galen never seemed to suggest that animals could serve as models for human diseases. Most early physicians who can be considered to have been students of disease developed their medical knowledge by observing the sick under their care. 1 early medical investigator

  18. Keeper-Animal Interactions: Differences between the Behaviour of Zoo Animals Affect Stockmanship.

    Science.gov (United States)

    Ward, Samantha J; Melfi, Vicky

    2015-01-01

    Stockmanship is a term used to describe the management of animals with a good stockperson someone who does this in a in a safe, effective, and low-stress manner for both the stock-keeper and animals involved. Although impacts of unfamiliar zoo visitors on animal behaviour have been extensively studied, the impact of stockmanship i.e familiar zoo keepers is a new area of research; which could reveal significant ramifications for zoo animal behaviour and welfare. It is likely that different relationships are formed dependant on the unique keeper-animal dyad (human-animal interaction, HAI). The aims of this study were to (1) investigate if unique keeper-animal dyads were formed in zoos, (2) determine whether keepers differed in their interactions towards animals regarding their attitude, animal knowledge and experience and (3) explore what factors affect keeper-animal dyads and ultimately influence animal behaviour and welfare. Eight black rhinoceros (Diceros bicornis), eleven Chapman's zebra (Equus burchellii), and twelve Sulawesi crested black macaques (Macaca nigra) were studied in 6 zoos across the UK and USA. Subtle cues and commands directed by keepers towards animals were identified. The animals latency to respond and the respective behavioural response (cue-response) was recorded per keeper-animal dyad (n = 93). A questionnaire was constructed following a five-point Likert Scale design to record keeper demographic information and assess the job satisfaction of keepers, their attitude towards the animals and their perceived relationship with them. There was a significant difference in the animals' latency to appropriately respond after cues and commands from different keepers, indicating unique keeper-animal dyads were formed. Stockmanship style was also different between keepers; two main components contributed equally towards this: "attitude towards the animals" and "knowledge and experience of the animals". In this novel study, data demonstrated unique dyads

  19. Keeper-Animal Interactions: Differences between the Behaviour of Zoo Animals Affect Stockmanship.

    Directory of Open Access Journals (Sweden)

    Samantha J Ward

    Full Text Available Stockmanship is a term used to describe the management of animals with a good stockperson someone who does this in a in a safe, effective, and low-stress manner for both the stock-keeper and animals involved. Although impacts of unfamiliar zoo visitors on animal behaviour have been extensively studied, the impact of stockmanship i.e familiar zoo keepers is a new area of research; which could reveal significant ramifications for zoo animal behaviour and welfare. It is likely that different relationships are formed dependant on the unique keeper-animal dyad (human-animal interaction, HAI. The aims of this study were to (1 investigate if unique keeper-animal dyads were formed in zoos, (2 determine whether keepers differed in their interactions towards animals regarding their attitude, animal knowledge and experience and (3 explore what factors affect keeper-animal dyads and ultimately influence animal behaviour and welfare. Eight black rhinoceros (Diceros bicornis, eleven Chapman's zebra (Equus burchellii, and twelve Sulawesi crested black macaques (Macaca nigra were studied in 6 zoos across the UK and USA. Subtle cues and commands directed by keepers towards animals were identified. The animals latency to respond and the respective behavioural response (cue-response was recorded per keeper-animal dyad (n = 93. A questionnaire was constructed following a five-point Likert Scale design to record keeper demographic information and assess the job satisfaction of keepers, their attitude towards the animals and their perceived relationship with them. There was a significant difference in the animals' latency to appropriately respond after cues and commands from different keepers, indicating unique keeper-animal dyads were formed. Stockmanship style was also different between keepers; two main components contributed equally towards this: "attitude towards the animals" and "knowledge and experience of the animals". In this novel study, data demonstrated

  20. 心血管疾病研究者对动物实验伦理认知度调查与分析%Investigation and Analysis of Animal Experiment Ethics Cognition in Cardiovascular Disease Researchers

    Institute of Scientific and Technical Information of China (English)

    崔永春; 田忠; 唐跃; 孙嘉康; 吴爱丽; 刘晓鹏; 罗富良

    2013-01-01

    Objective To find out animal experiment ethics cognition in the cardiovascular disease researchers to provide new strategies in training for animal experiment ethics. Method Self-designed questionnaire about animal experiment ethics was completed in 197 cardiovascular disease researchers performed animal experiments in animal experimental center, Fuwai Hospital from January 1 , 2009 to April 30, 2012. Result All of the subjects believed that animal experiment ethics was necessary for animal s' health and happiness. Good score of animal welfare and ethical knowledge was found in 54. 3% of subjects, qualified score in 35. 5% , and unqualified score in 10. 2% . All the unqualified subjects were the graduate students of 20 ~ 30 years old and without animal experiment research experience. Conclusion It is necessary to strengthen the training on experimental animal ethics, especially for the graduate students who would take part in animal experiments.%目的 了解不同层次心血管疾病研究者对于现有实验动物福利保护和动物伦理知识的认知,为动物实验伦理培训提供新策略,为进一步完善实验动物福利保护措施和伦理规制提供依据.方法 选择从2009年1月1日至2012年6月30日在中国医学科学院阜外心血管病医院动物实验中心开展动物实验的197名研究者开展问卷调查,根据《北京市实验动物福利伦理审查指南》自行设计调查问卷,并对结果进行分析.结果 对动物福利与伦理知识的认知得分,54.3%良好,35.5%合格,10.2%不合格,不合格者均为年龄20 ~ 30岁之间无动物实验科研经历的研究生.结论 研究者对动物福利与伦理认知度参差不齐,有必要加强实验动物伦理培训,尤其是对有动物实验需求的新入学的研究生.

  1. Carbohydrates Through Animation: Preliminary Step

    Directory of Open Access Journals (Sweden)

    J.K. Sugai

    2004-05-01

    Full Text Available Methods of education are changing, so the educational tools must change too. The developmentof the systems of information and communication gave the opportunity to bring new technology tothe learning process. Modern education needs interactive programs that may be available to theacademic community, in order to ease the learning process and sharing of the knowledge. Then,an educational software on Carbohydrates is being developed using concept maps and FLASH-MXanimations program, and approached through six modules. The introduction of Carbohydrates wasmade by the module Carbohydrates on Nature, which shows the animations gures of a teacher andstudents, visiting a farm, identifying the carbohydrates found in vegetables, animals, and microor-ganisms, integrated by links containing short texts to help understanding the structure and functionof carbohydrates. This module was presented, as pilot experiment, to teachers and students, whichdemonstrated satisfaction, and high receptivity, by using animation and interactivitys program asstrategy to biochemistrys education. The present work is part of the project Biochemistry throughanimation, which is having continuity.

  2. 新疆昌吉部分地区动物感染恙虫病东方体调查%Investigation on animal natural infection of Orientia tsutsugamushi in some areas of Changji area in Xinjiang

    Institute of Scientific and Technical Information of China (English)

    任立松; 党荣理; 刘晓明; 高金拽; 马德新

    2011-01-01

    目的 了解新疆昌吉部分地区野生动物自然感染恙虫病东方体(0t)的情况.方法 采用多种方法 捕鼠类,提取DNA,应用巢式PCR检测Ot-Sta56基因;阳性核苷酸序列片段测序,通过美国国家生物技术信息中心网站对基因序列进行BLAST比较分析.结果 共捕获鼠432只、鸟类53只,仅在木垒县的鼠类、鸟类脾样本中检测到阳性片段,感染率分别为5.3%、11.1%;其他县市未检测到阳性.DNA序列分析表明,鼠类、鸟类阳性标本中扩增产物的核苷酸序列相同,碱基长度均为442 bp.BLAST表明目的 基因与Karp型的碱基序列同源性最高(98.5%),应属于Karp型.结论 新疆昌吉地区木垒县啮齿类及鸟类动物中可能存在Ot感染.%Objective To investigate the state of natural infection of Orientia tsutsugamushi(Ot) in Changji area of Xinjiang, china. Methods DNAs were extracted from spleens of the captured mice and bloods of the sheep, and nested-polymerase chain reaction (nPCR) technique was used to detect the Ot-Sta 56 gene. Selected positive samples were sequenced and analyzed by NCBI and analyzed in BLAST. Results A total of 432 rodents and 53 birds were captured in Changji area. Positive samples were found in the rodents and birds which were captured in Mulei area. The prevalence of Ot in rodents and birds were 5.3% and 11.1%, respective. Infection was not found in animals living in the other areas. The Sta56 gene nucleotide sequence homology to Karp strain was 98.5%. Conclusion Our findings of indicated that infections of Ot did exist in rodents and birds in Mulei area. It provides evidence for further investigation on the scrub typhus fuci in this area.

  3. Toxoplasmosis in animals and humans

    Science.gov (United States)

    T. gondii is one of the most studied parasites.It causes disease in virtually all warm blooded animals Many scientists use T. gondii to investigate problems in cell biology and genetics. The book is divided into 19 chapters. Chapter 1 deals with biology. Chapter 2, which deals with toxoplasmosis...

  4. Animal husbandry and experimental design.

    Science.gov (United States)

    Nevalainen, Timo

    2014-01-01

    If the scientist needs to contact the animal facility after any study to inquire about husbandry details, this represents a lost opportunity, which can ultimately interfere with the study results and their interpretation. There is a clear tendency for authors to describe methodological procedures down to the smallest detail, but at the same time to provide minimal information on animals and their husbandry. Controlling all major variables as far as possible is the key issue when establishing an experimental design. The other common mechanism affecting study results is a change in the variation. Factors causing bias or variation changes are also detectable within husbandry. Our lives and the lives of animals are governed by cycles: the seasons, the reproductive cycle, the weekend-working days, the cage change/room sanitation cycle, and the diurnal rhythm. Some of these may be attributable to routine husbandry, and the rest are cycles, which may be affected by husbandry procedures. Other issues to be considered are consequences of in-house transport, restrictions caused by caging, randomization of cage location, the physical environment inside the cage, the acoustic environment audible to animals, olfactory environment, materials in the cage, cage complexity, feeding regimens, kinship, and humans. Laboratory animal husbandry issues are an integral but underappreciated part of investigators' experimental design, which if ignored can cause major interference with the results. All researchers should familiarize themselves with the current routine animal care of the facility serving them, including their capabilities for the monitoring of biological and physicochemical environment. PMID:25541541

  5. Research investigations in oil shale, tar sand, coal research, advanced exploratory process technology, and advanced fuels research: Volume 1 -- Base program. Final report, October 1986--September 1993

    Energy Technology Data Exchange (ETDEWEB)

    Smith, V.E.

    1994-05-01

    Numerous studies have been conducted in five principal areas: oil shale, tar sand, underground coal gasification, advanced process technology, and advanced fuels research. In subsequent years, underground coal gasification was broadened to be coal research, under which several research activities were conducted that related to coal processing. The most significant change occurred in 1989 when the agreement was redefined as a Base Program and a Jointly Sponsored Research Program (JSRP). Investigations were conducted under the Base Program to determine the physical and chemical properties of materials suitable for conversion to liquid and gaseous fuels, to test and evaluate processes and innovative concepts for such conversions, to monitor and determine environmental impacts related to development of commercial-sized operations, and to evaluate methods for mitigation of potential environmental impacts. This report is divided into two volumes: Volume 1 consists of 28 summaries that describe the principal research efforts conducted under the Base Program in five topic areas. Volume 2 describes tasks performed within the JSRP. Research conducted under this agreement has resulted in technology transfer of a variety of energy-related research information. A listing of related publications and presentations is given at the end of each research topic summary. More specific and detailed information is provided in the topical reports referenced in the related publications listings.

  6. RETHINKING THE ANIMATE, RE-ANIMATING THOUGHT

    Directory of Open Access Journals (Sweden)

    Tim Ingold

    2013-12-01

    Full Text Available Animism is often described as the imputation of life to inert objects. Such imputation is more typical of people in western societies who dream of finding life on other planets than of indigenous peoples to whom the label of animism has classically been applied. These peoples are united not in their beliefs but in a way of being that is alive and open to a world in continuous birth. In this animic ontology, beings do not propel themselves across a ready-made world but rather issue forth through a world-in-formation, along the lines of their relationships. To its inhabitants this weather-world, embracing both sky and earth, is a source of astonishment but not surprise. Re-animating the ‘western’ tradition of thought means recovering the sense of astonishment banished from offi cial science.

  7. Multidrug-resistant Salmonella Typhimurium in Four Animal Facilities

    OpenAIRE

    Wright, Jennifer G.; Tengelsen, Leslie A.; Smith, Kirk E.; Bender, Jeff B.; Frank, Rodney K.; Grendon, John H.; Rice, Daniel H.; Thiessen, Ann Marie B.; Gilbertson, Catherine Jo; Sivapalasingam, Sumathi; Barrett, Timothy J.; Besser, Thomas E.; Dale D Hancock; Frederick J Angulo

    2005-01-01

    In 1999 and 2000, 3 state health departments reported 4 outbreaks of gastrointestinal illness due to Salmonella enterica serotype Typhimurium in employees, clients, and client animals from 3 companion animal veterinary clinics and 1 animal shelter. More than 45 persons and companion animals became ill. Four independent investigations resulted in the testing of 19 human samples and >200 animal samples; 18 persons and 36 animals were culture-positive for S. Typhimurium. One outbreak was due to ...

  8. Companion Animals Symposium: Environmental enrichment for companion, exotic, and laboratory animals.

    Science.gov (United States)

    Morris, C L; Grandin, T; Irlbeck, N A

    2011-12-01

    Animal scientists have an extraordinary burden to promote the health and well-being of all animals in their care. Promoting species- or breed-appropriate behaviors through proper training and enrichment, regardless of animal housing, should be a paramount concern for all animal scientists working with exotic animals, laboratory animals, shelter animals, or privately owned pet animals. Developing ideal training and enrichment programs for any species begins with understanding basic behavior patterns and emotional systems of animals. The basic emotional systems in mammals have been extensively mapped; however, most of these studies are in the neuroscience literature and seldom read by animal science professionals. The emotional circuits for fear have been well documented through studies demonstrating that lesions to the amygdala will block both conditioned and unconditioned fear behaviors. Additionally, other core emotional systems including seeking (i.e., approaching a novel stimulus), rage, panic (e.g., separation stress), play, lust (i.e., sex drive), and care (e.g., mother-young nurturing behavior) have been identified. More recent neuroscience research has discovered the subcortical brain regions that drive different types of seeking behaviors. Research to increase the understanding of the emotional systems that drive both abnormal and normal animal behaviors could greatly improve animal welfare by making it possible to provide more effective environmental enrichment programs. Enrichment devices and methods could be specifically designed to enable the expression of highly motivated behaviors that are driven by emotional circuits in the brain. The objective of this paper is to increase awareness of animal scientists to the field of neuroscience studying animal emotions and the application of that science to improve the welfare of captive exotic animals, laboratory animals, and pets with environmental enrichment. PMID:22110089

  9. Interaction between animal personality and animal cognition

    OpenAIRE

    Claudio CARERE, Charles LOCURTO

    2011-01-01

    The study of animal personality has attracted considerable attention, as it has revealed a number of similarities in personality between humans and several nonhuman species. At the same time the adaptive value and evolutionary maintenance of different personalities are the subject of debate. Since Pavlov’s work on dogs, students of comparative cognition have been aware that animals display vast individual differences on cognitive tasks, and that these differences may not be entirely accounted...

  10. Animals in Education.

    Science.gov (United States)

    Rowan, Andrew N.

    1981-01-01

    Summarizes viewpoints on the use of animals in science experiments in the biology classroom, including those of teachers, education researchers, biomedical scientists, science education administrators, and animal welfare advocates. (Author/CS)

  11. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... FDA Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & ... by Product Area Product Areas back Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & ...

  12. "Name" that Animal

    Science.gov (United States)

    Laird, Shirley

    2010-01-01

    In this article, the author describes a texture and pattern project. Students started by doing an outline contour drawing of an animal. With the outline drawn, the students then write one of their names to fit "inside" the animal.

  13. Morris Animal Foundation

    Science.gov (United States)

    ... the transmission of serious illnesses. Read more » Morris Animal Foundation Receives $750,000 Grant for Cancer Studies. ... Give Partners Become a Partner Meet Our Partners Animal Lovers Our Work Ways to Give Pet Health ...

  14. Field lysimeter investigations: Low-level waste data base development program for fiscal year 1996. Annual report; Volume 9

    Energy Technology Data Exchange (ETDEWEB)

    McConnell, J.W. Jr.; Rogers, R.D.; Larsen, I.L. [Lockheed Martin Idaho Technologies Co., Idaho Falls, ID (United States). Idaho National Engineering and Environmental Lab.; Jastrow, J.D. [Argonne National Lab., IL (United States); Sanford, W.E. [Oak Ridge National Lab., TN (United States); Sullivan, T.M.; Fuhrmann, M. [Brookhaven National Lab., Upton, NY (United States)

    1997-08-01

    A data base development program, funded by the US Nuclear Regulatory Commission, is (a) studying the degradation effects in organic ion-exchange resins caused by radiation, (b) examining the adequacy of test procedures recommended in the Branch Technical Position on Waste Form to meet the requirements of 10 CFR 61 using solidified ion-exchange resins, (c) obtaining performance information on solidified ion-exchange resins in a disposal environment, and (d) determining the condition of liners used to dispose the ion-exchange resins. During the field testing experiments, both portland type 1--2 cement and Dow vinyl ester-styrene waste form samples were tested in lysimeter arrays located at Argonne National Laboratory-East (ANL-E) in Illinois and at Oak Ridge National Laboratory (ORNL). The study was designed to provide continuous data on nuclide release and movement, as well as environmental conditions, over an extended period. Those experiments have been shut down and are to be exhumed. This report discusses the plans for removal, sampling, and analysis of waste form and soil cores from the lysimeters. Results of partition coefficient determinations are presented, as well as application of a source term computer code using those coefficients to predict the lysimeter results. A study of radionuclide-containing colloids associated with the leachate waters removed from these lysimeters is described. An update of upward migration of radionuclides in the sand-filled lysimeter at ORNL is included.

  15. Simple Program to Investigate Hysteresis Damping Effect of Cross-Ties on Cables Vibration of Cable-Stayed Bridges

    Directory of Open Access Journals (Sweden)

    Panagis G. Papadopoulos

    2012-01-01

    Full Text Available A short computer program, fully documented, is presented, for the step-by-step dynamic analysis of isolated cables or couples of parallel cables of a cable-stayed bridge, connected to each other and possibly with the deck of the bridge, by very thin pretensioned wires (cross-ties and subjected to variation of their axial forces due to traffic or to successive pulses of a wind drag force. A simplified SDOF model, approximating the fundamental vibration mode, is adopted for every individual cable. The geometric nonlinearity of the cables is taken into account by their geometric stiffness, whereas the material nonlinearities of the cross-ties include compressive loosening, tensile yielding, and hysteresis stress-strain loops. Seven numerical experiments are performed. Based on them, it is observed that if two interconnected parallel cables have different dynamic characteristics, for example different lengths, thus different masses, weights, and geometric stiffnesses, too, or if one of them has a small additional mass, then a single pretensioned very thin wire, connecting them to each other and possibly with the deck of the bridge, proves effective in suppressing, by its hysteresis damping, the vibrations of the cables.

  16. Field lysimeter investigations: Low-level waste data base development program for fiscal year 1996. Annual report; Volume 9

    International Nuclear Information System (INIS)

    A data base development program, funded by the US Nuclear Regulatory Commission, is (a) studying the degradation effects in organic ion-exchange resins caused by radiation, (b) examining the adequacy of test procedures recommended in the Branch Technical Position on Waste Form to meet the requirements of 10 CFR 61 using solidified ion-exchange resins, (c) obtaining performance information on solidified ion-exchange resins in a disposal environment, and (d) determining the condition of liners used to dispose the ion-exchange resins. During the field testing experiments, both portland type 1--2 cement and Dow vinyl ester-styrene waste form samples were tested in lysimeter arrays located at Argonne National Laboratory-East (ANL-E) in Illinois and at Oak Ridge National Laboratory (ORNL). The study was designed to provide continuous data on nuclide release and movement, as well as environmental conditions, over an extended period. Those experiments have been shut down and are to be exhumed. This report discusses the plans for removal, sampling, and analysis of waste form and soil cores from the lysimeters. Results of partition coefficient determinations are presented, as well as application of a source term computer code using those coefficients to predict the lysimeter results. A study of radionuclide-containing colloids associated with the leachate waters removed from these lysimeters is described. An update of upward migration of radionuclides in the sand-filled lysimeter at ORNL is included

  17. Investigation on infection in mankind and animal of Orientia tsutsugamushi in some areas in Xinjiang, China%新疆部分地区人群及动物感染恙虫病东方体调查

    Institute of Scientific and Technical Information of China (English)

    任立松; 党荣理; 马德新; 高金拽; 刘小明

    2012-01-01

    Objective To investigate the infection in mankind and animal of Orientia tsutsugamushi in Xinjiang, China. Methods DNAs were extracted from spleens of the captured mice and the blood of the worker and the Chigger mite were seized from the rodent body surface. Nested polymerase chain reaction (nPCR) technique was used to detect the Ot Sta 56 gene. Some positive samples were sequenced and analyzed by BLAST. Results We detected the positive results from the pasturing worker, rodents (M.musculus, C.migratorius , R.opimus , L. lute us, M.baibacina), birds (L. passer domesticus, T.motacilla cinerea) and sheep. Orientia tsutsugamushi were isolated from the rodent spleen and Chigger mite. The Sta56 gene nucleotide sequence was homology to Karp strain. The Saitama strain could exist in certain areas. Conclusion The infection of Orientia tsutsugamushi in mankind and animal existed in Xinjiang.%目的 调查新疆部分地区人群及动物感染恙虫病东方体(Ot)情况,并对媒介昆虫进行调查.方法 采用多种方法捕获可能感染Ot动物取脾,当地牧民静脉取血,从野鼠体表捕获恙螨,用试剂盒提取DNA,应用巢式PCR( nPCR)检测Ot-Sta56基因;接种昆明小白鼠进行Ot病原传代分离.结果 共采取人群血液2 430份,在6份血液中检测并分离到Ot;捕获动物13种5 783个(只),从5种啮齿动物(小家鼠、灰仓鼠、大砂土鼠、草原兔尾鼠、灰旱獭)、2种鸟类(麻雀、灰腹鹡鸰)的脾中检测并分离到Ot,从绵羊血液中检测到Ot.其他动物体内未检测到Ot.从野鼠体表分离恙螨5种,从博乐纤恙螨体内检测分离到Ot.基因序列分析表明,新疆地区存在恙虫病东方体的基因型以Karp型为主,可能存在Saitama型.结论 新疆地区存在人群及动物感染Ot,其基因型以Karp为主,可能存在Saitama型.

  18. Generic Face Animation

    OpenAIRE

    Cerda, Mauricio; Valenzuela, Renato; Hitschfeld-Kahler, Nancy; Terissi, Lucas; Gomez, Juan C.

    2010-01-01

    International audience In computer vision, the animation of objects has attracted a lot attention, specially the animations of 3D face models. The animation of face models requires in general to manually adapt each generic movement (open/close mouth) to each specific head geometry. In this work we propose a technique for the animation of any face model avoiding most of the manual intervention. In order to achieve this we assume that: (1) faces, despite obvious differences are quite similar...

  19. Biopolitics: Animals, meat, food

    OpenAIRE

    Janović Nikola

    2009-01-01

    The general idea of this text is to reflect biopolitical constitution of the society and its implications related to the issues of animal welfare. Since animal in biopolitical formation is technically reduced to an object - commodity for contentment of the industry and of the people needs - critical public advisories are calling from moral, ethical and legal standpoint for attention to the fact that is necessary to protect animals from the unnecessary exploitation. It is obvious that animal p...

  20. Veterinary Services Program

    Data.gov (United States)

    Federal Laboratory Consortium — Mission: To provide quality veterinary medical care and environmental enrichment programs for all animals, representing nine different species. To provide guidance...