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Sample records for angina inestable primaria

  1. Diferencias en las características clínicas y en la evolución intrahospitalaria entre la angina inestable primaria y secundaria en ancianos

    OpenAIRE

    Giorgi, Mariano A; Andrés Ahuad Guerrero; Pablo Schygiel; Fernando Sokn; Guillermo Suárez; Jorge E. Trongé

    2007-01-01

    IntroducciónLa angina inestable (AI) se clasifica en primaria (AP) y secundaria (AS) sobre la base de la presencia o no de causas secundarias de isquemia. Estas condiciones son frecuentes en los ancianos y podrían influir en su pronóstico.ObjetivoEl presente trabajo se llevó a cabo con el objetivo de evaluar las características clínicas y la evolución intrahospitalaria de ancianos con AI primaria y secundaria.Material y métodosSe registraron 298 ancianos (edad ≥ 75 años) con diagnóstico final...

  2. Diferencias en las características clínicas y en la evolución intrahospitalaria entre la angina inestable primaria y secundaria en ancianos

    Directory of Open Access Journals (Sweden)

    Mariano A. Giorgi

    2007-01-01

    Full Text Available IntroducciónLa angina inestable (AI se clasifica en primaria (AP y secundaria (AS sobre la base de la presencia o no de causas secundarias de isquemia. Estas condiciones son frecuentes en los ancianos y podrían influir en su pronóstico.ObjetivoEl presente trabajo se llevó a cabo con el objetivo de evaluar las características clínicas y la evolución intrahospitalaria de ancianos con AI primaria y secundaria.Material y métodosSe registraron 298 ancianos (edad ≥ 75 años con diagnóstico final de AI. La muestra se dividió, según la presencia de causas secundarias de isquemia (anemia, taquicardia, hipertensión no controlada, infección, hipertiroidismo, en dos grupos: AS y AP. Secompararon antecedentes, características clínicas al ingreso, tratamientos, procedimientos y la ocurrencia de muerte y muerte o infarto en la fase intrahospitalaria. Se identificaronpredictores univariados de mala evolución.ResultadosCincuenta y dos pacientes (17,45% tenían AS y 246 (82,5% padecían AP. Los pacientes con AS eran más añosos y tenían mayores registros de tensión arterial y de frecuencia cardíaca al ingreso. El tratamiento médico, la cinecoronariografía y la revascularización se utilizaron menos en el grupo AS. La mortalidad (7,7% versus 6,9% [p = 1,00; OR (IC 95 = 1,12 (0,36-3,48] AS y AP, respectivamente y la combinación de muerte o infarto (7,7% versus 9,7%[p = 0,79; OR (CI 95 = 0,77 (0,25-2,32] AS y AP, respectivamente fueron similares. Los predictores univariados de muerte o infarto fueron infradesnivel del ST y desarrollo de insuficiencia cardíaca para ambos grupos y la refractariedad y necesidad de coronariografía y revascularización para el grupo AP. ConclusiónLa AS es una causa común de isquemia en los ancianos y, pese a que requiere un manejo diferente, orientado a su etiología, tiene un pronóstico similar al de la AP.

  3. Analgesia epidural torácica para el tratamiento de la angina inestable Thoracal epidural analgesia for the management of unstable angina

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    M. Castro

    2005-07-01

    Full Text Available La miocardiopatía isquémica en pacientes con angina inestable refractaria al tratamiento médico constituye un escenario clínico complicado. Una anatomía desfavorable o un riesgo quirúrgico excesivamente alto pueden desaconsejar la realización de una angioplastia o de una cirugía de derivación coronaria. En este artículo se pretende revisar la utilización de la analgesia/anestesia epidural torácica para el tratamiento y estabilización de este tipo de pacientes, a través de una breve descripción de la fisiopatología de la isquemia cardiaca, estudios experimentales en animales y humanos, uso en cirugía cardiaca y efectos secundarios.Ischemic cardiomyopathy in patients with unstable angina refractory to medical therapy is a difficult medical condition. Unfavorable anatomy or excessive surgical risk can advise against the performance of angioplasty or coronary bypass surgery. This study has reviewed the use of thoracal epidural analgesia/anesthesia for the management and stabilization of this type of patients, with a brief description of the physiopathology of cardiac ischemia, experimental studies in animals and human beings, use of cardiac surgery and side effects.

  4. Variabilidad de la frecuencia cardíaca en pacientes con angina inestable: correlación con otros marcadores pronósticos

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    Oswaldo Gutiérrez Sotelo

    2004-01-01

    Full Text Available Introducción: La importancia del análisis de la variabilidad de la frecuencia cardíaca (VFC está bien establecida como marcador pronóstico en pacientes que han tenido infarto agudo de miocardio y en otras cardiopatías. El objetivo de este estudio es establecer la correlación entre las variables de VFC y los índices pronósticos tradicionales en angina inestable Materiales y Métodos: Se reclutaron prospectivamente pacientes con diagnóstico de angina inestable. Se consignaron indicadores de riesgo cardiovascular clínicos (angor de reposo refractario, hipotensión arterial, insuficiencia cardíaca, presencia de cambios dinámicos en el ST-T, fracción de eyección =40% y los hallazgos angiográficos (2 ó más vasos, conformándose entonces dos grupos, de alto riesgo y de bajo riesgo. A todos los pacientes se les realizó un registro electrocardiográfico de 5 minutos y se analizaron diversas variables de VFC en dominio de tiempo y de frecuencia mediante un programa de computadora. Estas variables se compararon entre ambos grupos. Resultados: Se reclutaron 63 pacientes (44 hombres, 70% con edad promedio de 63 + 10.4 años (35-90; 46 se consideraron de alto riesgo por cambios electrocardiográficos dinámicos y la fracción de eyección disminuida y 17 de bajo riesgo. En el primer grupo, el poder espectral total fue significativamente menor que en el grupo de bajo riesgo (p=0.04. La banda de baja frecuencia mostró diferencia pero sin alcanzar significancia estadística (p=0.07 y otras variables como el SDNN, el NN50 y la banda de baja frecuencia, mostraron sólo tendencia de ser menores en el grupo de alto riesgo. Conclusión: En pacientes con angina inestable de alto riesgo, la presencia de indicadores pronósticos tiene correlación con una menor VFC en dominio de frecuencia.Introduction: The usefullness of heart rate variability (HRV analysis is well known in myocardial infarction as in other cardiac diseases as a prognostic tool. The

  5. Comparação de biomarcadores inflamatórios entre pacientes diabéticos e não-diabéticos com angina instável Comparación de biomarcadores inflamatorios entre pacientes diabéticos y no-diabéticos con angina inestable Comparison of inflammatory biomarkers between diabetic and non-diabetic patients with unstable angina

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    Marçal de Oliveira Huoya

    2009-04-01

    concentração de marcadores inflamatórios de fase aguda, independentemente do estado metabólico.FUNDAMENTO: Pocos estudios compararon la actividad inflamatoria entre pacientes diabéticos y no-diabéticos con síndrome coronario agudo, y todavía no se publicó ninguno que investigara solamente a los portadores de angina inestable (AI. OBJETIVO: Este estudio tuvo dos objetivos. En primer lugar, comparar los niveles séricos de proteína C reactiva (PCR y interleuquina-6 (IL-6 en pacientes diabéticos y no-diabéticos con angina inestable (AI para determinar si la diferencia en la actividad inflamatoria justifica el empeoramiento pronóstico en los pacientes diabéticos. En segundo, evaluar la correlación entre los marcadores inflamatorios y el perfil metabólico en pacientes diabéticos y entre la respuesta inflamatoria y los desenlaces hospitalarios, como muerte, infarto agudo de miocardio, insuficiencia cardiaca congestiva y tiempo de hospitalización. MÉTODOS: Estudio de cohorte prospectiva de 90 pacientes consecutivos, ingresados a la Unidad de Dolor Torácico con angina inestable. Se dividieron a los pacientes en dos grupos: diabéticos y no-diabéticos. Los niveles séricos de PCR e IL-6, el perfil metabólico y el conteo de leucocitos se obtuvieron al ingreso al hospital. RESULTADOS: De todos los pacientes analizados, 42 (47% eran diabéticos (edad 62 ± 9 y 48 (53% no eran diabéticos (edad 63 ± 12. No se encontraron diferencias entre la mediana de la PCR (1,78 vs. 2,23 mg/l, p = 0,74 y de la IL-6 (0 vs. 0 pg/ml, p = 0,31 entre los dos grupos. Hubo una correlación positiva entre la PCR y el colesterol total (rs = 0, 21, p = 0, 05, la PCR y el colesterol LDL (rs = 0,22, p = 0,04 y la PCR y el conteo de leucocitos (rs = 0,32, p = 0,02 en los dos grupos. No se encontró ninguna asociación entre los marcadores inflamatorios y los desenlaces hospitalarios. CONCLUSIÓN: No encontramos diferencia en la actividad inflamatoria entre los pacientes diabéticos y no

  6. Stable angina

    Science.gov (United States)

    ... include: Coronary angiography Blood cholesterol profile ECG Exercise tolerance test (stress test or treadmill test) Nuclear medicine ( ... PhD, and the A.D.A.M. Editorial team. Related MedlinePlus Health Topics Angina Browse the Encyclopedia ...

  7. Unstable angina

    Science.gov (United States)

    ... pressure High LDL cholesterol Low HDL cholesterol Male gender Sedentary lifestyle (not getting enough exercise) Obesity Older ... Seek medical attention if you have new, unexplained chest pain or pressure. If you have had angina before, call your health ...

  8. What Causes Angina?

    Science.gov (United States)

    ... this page from the NHLBI on Twitter. What Causes Angina? Underlying Causes Angina usually is a symptom of coronary heart ... and cause angina or a heart attack . Immediate Causes Many factors can trigger angina pain, depending on ...

  9. Pharmacotherapy of Vasospastic Angina.

    Science.gov (United States)

    Harris, Justin R; Hale, Genevieve M; Dasari, Tarun W; Schwier, Nicholas C

    2016-09-01

    Vasospastic angina is a diagnosis of exclusion that manifests with signs and symptoms, which overlap with obstructive coronary artery disease, most often ST-segment elevation myocardial infarction. The pharmacotherapy that is available to treat vasospastic angina can help ameliorate angina symptoms. However, the etiology of vasospastic angina is ill-defined, making targeted pharmacotherapy difficult. Most patients receive pharmacotherapy that includes calcium channel blockers and/or long-acting nitrates. This article reviews the efficacy and safety of the pharmacotherapy used to treat vasospastic angina. High-dose calcium channel blockers possess the most evidence, with respect to decreasing angina incidence, frequency, and duration. However, not all patients respond to calcium channel blockers. Nitrates and/or alpha1-adrenergic receptor antagonists can be used in patients who respond poorly to calcium channel blockers. Albeit, evidence for use of nitrates and alpha1-adrenergic receptor antagonists in vasospastic angina is not as robust as calcium channel blockers and can exacerbate adverse effects when added to calcium channel blocker therapy. Despite having a clear benefit in patients with obstructive coronary artery disease, the benefit of beta-adrenergic receptor antagonists, statins, and aspirin remains unclear. More data are needed to elucidate whether or not these agents are beneficial or harmful to patients being treated for vasospastic angina. Overall, the use of pharmacotherapy for the treatment of vasospastic angina should be guided by patient-specific factors, such as tolerability, adverse effects, drug-drug, and drug-disease interactions. PMID:27081186

  10. How Is Angina Treated?

    Science.gov (United States)

    ... may be advised to get annual flu shots. Medical Procedures If lifestyle changes and medicines don't control angina, you may need a medical procedure to treat the underlying heart disease. Both angioplasty ( ...

  11. EVOLUCIÓN CLÍNICA DE PACIENTES CON INFARTO AGUDO DE MIOCARDIO TRATADOS CON ANGIOPLASTIA PRIMARIA / Clinical evolution of patients with acute myocardial infarction treated with primary angioplasty

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    Ernesto del Pino Sánchez

    2012-07-01

    Full Text Available ResumenIntroducción y objetivos: La angioplastia primaria restablece de manera rápida y mantenida la permeabilidad de la arteria coronaria responsable del infarto agudo de miocardio, disminuye significativamente la mortalidad, y mejora el pronóstico y la calidad de vida a largo plazo. El objetivo fue describir la evolución clínica de los pacientes con infarto agudo de miocardio tratados con angioplastia primaria. Método: Estudio descriptivo, longitudinal y prospectivo con 69 pacientes, recepcionados de 8:00 am a 4:00 pm, tratados con angioplastia primaria en el Instituto de Cardiología y Cirugía Cardiovascular, desde el 1 de julio de 2007 hasta el 31 de diciembre de 2008. Se realizó seguimiento clínico durante 180 días, donde se evaluó la frecuencia de sucesos clínicos mayores: muerte, reinfarto, angina postinfarto e inestable, necesidad de nueva revascularización y hemorragia mayor. Resultados: El tabaquismo y la hipertensión arterial tuvieron una prevalencia elevada. La localización inferior del infarto y la enfermedad de un vaso fueron las más frecuentes. Prevaleció el resultado inmediato exitoso. Los casos fallidos se relacionaron, con la coronaria derecha, el flujo TIMI 0 - 1 y el tiempo de evolución mayor de seis horas. Los sucesos clínicos mayores en el seguimiento fueron escasos y más frecuentes durante los primeros 30 días de seguimiento. Conclusiones: La angioplastia primaria realizada durante las primeras seis horas después del comienzo de los síntomas, es un procedimiento eficaz para tratar el infarto agudo de miocardio, debido al predominio del resultado exitoso y la escasa frecuencia de sucesos clínicos mayores durante seis meses de seguimiento clínico. / AbstractIntroduction and Objectives: Primary coronary angioplasty reestablishes fast and sustained way the permeability of acute myocardial infarction related artery. It decreases the mortality, improves the prognosis and quality of life to long-term. The

  12. Identificación de variables predictivas de riesgo en la evaluación incial de la angina inestable.

    OpenAIRE

    Rueda Soriano, Joaquín

    2005-01-01

    RESUMEN Objetivo: 1. Conocer el perfil clínico y electrocardiográfico de los pacientes ingresados con síndrome coronario agudo sin elevación persistente del segmento ST (SCASEST). 2. Incidencia de eventos adversos isquémicos intrahospitalarios. 3. Identificar las variables que obtenidas en el ingreso, sean predictivas de eventos adversos intrahospitalarios. 4. Analizar la incidencia de eventos adversos a largo plazo 5. Identificar las variables predictivas de eventos adversos isquémicos a ...

  13. Angina de Prinzmetal Angina de Prinzmetal Prinzmetal's angina

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    Eduardo Contreras Zuniga

    2009-08-01

    Full Text Available Essa síndrome é causada por um espasmo focal de uma artéria coronária epicárdica, levando a isquemia miocárdica grave. Embora freqüentemente acredite-se que o espasmo ocorra em artérias sem estenose, muitos pacientes com angina de Prinzmetal apresentam espasmo adjacente a placas ateromatosas. A causa exata do espasmo não está bem definida, mas pode estar relacionada à hipercontratilidade do músculo liso vascular devido a mitógenos vasoconstrictores, leucotrienos ou serotonina. Em alguns pacientes, é uma manifestação de distúrbio vasoespástico e está associado à migrânea, fenômeno de Raynaud ou asma induzida por aspirina. Apresentamos um caso associado com depressão transitória do segmento ST.Este síndrome es causado por un espasmo focal de una arteria coronaria epicárdica, llevando a isquemia miocárdica grave. Aunque frecuentemente se crea que el espasmo ocurra en arterias sin estenosis, muchos pacientes con angina de Prinzmetal presentan espasmo adyacente a placas ateromatosas. La causa exacta del espasmo no está bien definida, pero puede estar relacionada a la hipercontractilidad del músculo liso vascular debido a mitógenos vasoconstrictores, leucotrienos o serotonina. En algunos pacientes, es una manifestación de disturbio vasoespástico y está asociado a la migraña, fenómeno de Raynaud o asma inducida por aspirina. Presentamos un caso asociado con depresión transitoria del segmento ST.This syndrome is due to focal spasm of an epicardial coronary artery, leading to severe myocardial ischemia. Although it is frequently thought that the spasm occurs in arteries without stenosis, many Prinzmetal patients have spasm adjacent to atheromatous plaques. The exact cause of the spasm has not been well defined, but it may be related to the hypercontractility of the vascular smooth muscle due to vasoconstrictor mitogens, leukotrienes, or serotonin. In some patients, it is a manifestation of a vasospastic disorder and it

  14. Management of refractory angina pectoris

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    Ristić Anđelka

    2004-01-01

    Full Text Available An increasing number of patients with coronary artery disease have ischemie symptoms that are unresponsive to both conventional medical therapy and revascularization techniques. The objective of this study was to define the population of patients with refractory angina pectoris and to present the therapeutic options currently available for this condition. Among many techniques, the enhanced external counterpulsation, transmyocardial laser revascularization and neurostimulation have been shown to reduce angina and to improve objective measures of myocardial ischemia in patients with refractory angina.

  15. How Can Angina Be Prevented?

    Science.gov (United States)

    ... changes and treating related conditions. Making Lifestyle Changes Healthy lifestyle choices can help prevent or delay angina and heart disease. To adopt a healthy lifestyle, you can: Quit smoking and avoid secondhand ...

  16. Medications for Angina (Beyond the Basics)

    Science.gov (United States)

    ... of medications used to treat stable angina: ● Nitrates ● Beta blockers ● Calcium channel blockers ● Ranolazine Nitrates or beta blockers are usually preferred for initial treatment of angina, ...

  17. Living with heart disease and angina

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000576.htm Living with heart disease and angina To use the sharing features on ... please enable JavaScript. Coronary artery disease - living with Heart Disease and Angina Coronary heart disease (CHD) is a ...

  18. Klinik der instabilen Angina pectoris

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    Auer J

    1999-01-01

    Full Text Available Die instabile Angina pectoris wird zu den akuten Koronarsyndromen gerechnet und weist als pathophysiologisches Substrat ein thrombotisches Ereignis auf dem Boden einer koronaren Endothelläsion auf. Aufgrund der Anamnese und unter Zuhilfenahme von EKG und serologischen Markern kann eine Risikostratifizierung von Patienten mit instabiler Angina pectoris vorgenommen werden. Je nach Risikoeinstufung und der damit möglichen prognostischen Abschätzung der klinischen Situation kann das weitere therapeutische Management stratifiziert werden. Im Rahmen der folgenden Übersicht werden anamnestische Kriterien für Definition und Klassifikation der instabilen Angina pectoris abgehandelt und darüber hinaus versucht, den Stellenwert der klinischen Untersuchung, der Echokardiographie und serologischer Tests für Risikoabschätzung und Therapieplanung dieser Patienten anzugeben.

  19. Bradycardiac angina: haemodynamic aspects and treatment.

    Science.gov (United States)

    Fowler, P B; Ikram, H; Maini, R N; Makey, A R; Kirkham, J S

    1969-01-11

    A patient with a sinus bradycardia and angina is described who was unable to increase his heart rate on vigorous exercise by more than a few beats. His severe angina was attributed to the bradycardia. Atrial pacing of his heart abolished his angina and increased his exercise tolerance. Circulatory changes at rest, on exertion, and with atrial pacing are described. The cause of angina in this patient is discussed. PMID:5761833

  20. STUDY OF VARIABLES IN UNSTABLE ANGINA

    OpenAIRE

    Vijay Kumar; Kashinath B; Sajjal; Shivraj B; Thirumala

    2014-01-01

    OBJECTIVES: Prevalence rates of coronary artery disease are reported to be very high in Asian Indians. Traditional risk factors alone fail to explain the high rates of coronary disease in Indians. Acute phase reactants C-reactive protein in Indian subjects with unstable angina were evaluated and compare them with suitable control to test the hypothesis that a relationship exists between acute phase reactants and unstable angina. METHODOLOGY: 50 cases unstable angina and 50...

  1. Myocardial ischemia and angina pectoris

    International Nuclear Information System (INIS)

    Ambulatory monitoring of ST segment changes was performed in 60 patients presenting with angina, positive ECG stress tests and coronary artery disease, 85% of ischemic ECG events were asymptomatic, 37% occurred with no increase in heart rate and 15% of episodes either lasted 20 minutes or more or fluctuated in severity. A controlled pilot study in ten patients showed depression. Radionuclide studies in 50 patients with angina and coronary artery disease have shown that stress (i.e., atrial pacing) produced different patterns of disturbed regional myocardial perfusion related to the patient's exercise capacity and eventually leading to a decrease in regional myocardial perfusion during the ischemic episode. ST segment depression appeared only after the decrease in regional myocardial perfusion. These findings combined with past research suggest that patients with angina and coronary artery disease can suffer frequent asymptomatic disturbances of the regional myocardial perfusion. The frequency of these episodes and the time course for the recovery of the metabolic consequences mean that segments of ventricular myocardium may be constantly abnormal. The relative importance of changes in coronary tone and malfunction of platelets in the diseased coronary tree needs to be examined in clinical research. Pilot studies of antiplatelet agents have shown a significant beneficial effect on episodes of ischemia occurring at night and those occurring without any increase in heart rate. The techniques and observations in these patients with coronary artery disease all suggest that acute transient regional myocardial ischemia is caused by a variety of mechnisms. Further research using objective methods is required to discover the causes of ischemia and to rationalize treatment. (orig./MG)

  2. Arteriographic morphology and intracoronary thrombus in patients with unstable angina, non-Q wave myocardial infarction and stable angina pectoris.

    Science.gov (United States)

    Hussain, K M; Gould, L; Bharathan, T; Angirekula, M; Choubey, S; Karpov, Y

    1995-03-01

    Coronary artery lesions were compared in 71 patients with unstable angina, 15 patients with non-Q wave myocardial infarction (MI), and 40 patients with stable angina. In the unstable angina group, 29 patients had new-onset angina, 31 had crescendo angina, and 11 had rest angina. In a subgroup of patients with unstable angina, three-vessel disease was less frequently (P < 0.05) seen in patients with new-onset angina (10.3%) than in the patients with crescendo angina (51.6%) or rest angina (54.5%). An angina-producing artery could be identified in 59 patients with unstable angina, in 11 with non-Q wave MI, and in 30 with stable angina. Type II eccentric stenosis (asymmetric narrowing with narrow neck and overhanging irregular edges) was present in 31 patients (52.5%; P < 0.01) with unstable angina, in 7 (63.6%; P < 0.01) with non-Q wave MI, and in only 2 (6.7%) with stable angina. Abrupt occlusion of a vessel was observed in 7 patients (11.9%) with unstable angina and in 2 (18.2%) with non-Q wave MI. None of the patients with stable angina had this type of occlusion. In the group of unstable angina and non-Q wave MI, angiographic evidence of intracoronary thrombi was present in 16 (27.1%) and 3 patients (27.3%), respectively, but in stable angina in only 1 patient (3.3%; P < 0.05). Intracoronary thrombi were most frequently found in rest angina (88%; P < 0.001) and crescendo angina (33.3%; P < 0.01) compared with new-onset angina (3.7%).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7879958

  3. Angina

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 71. Lange RA, Hillis LD. ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 72. Marrow DA, Boden WE. ...

  4. Las mutaciones inestables, nuevo reto para el consejo genético de enfermedades hereditarias

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    Patricia Cuenca

    2004-09-01

    Full Text Available Las mutaciones inestables constituyen un tipo de alteración genética descubierta en la década de los noventa. En condiciones normales, regiones específicas de los genes están constituidas por repeticiones de una secuencia corta que puede ser de tres, cuatro, cinco o más nucleótidos; por ejemplo CAG, CGG, ATTCT, etc. Este nuevo tipo de mutación consiste en un aumento en la cantidad de éstas repeticiones, lo que causa una alteración en la expresión de dichos genes. Son inestables porque se ha observado que el tamaño de la secuencia repetida varía cuando las células se dividen por mitosis o meiosis, lo cual tiene implicaciones sobre la herencia y por consiguiente sobre el consejo genético que debe brindarse a los afectados. Estas mutaciones se han encontrado en genes importantes para la función neurológica normal del ser humano, donde pueden alterar el transporte de los ARN desde el núcleo al citoplasma, provocar la inactivación del gen o producir una proteína con funciones nuevas. La mayoría de las enfermedades causadas por estas mutaciones afectan el sistema nervioso, son degenerativas y presentan el fenómeno de anticipación genética, es decir que los afectados dentro de una familia se enfermarán más jóvenes y en forma más severa con el paso de las generaciones. La cantidad de repeticiones de la secuencia repetida presenta una correlación negativa con la edad de manifestación, así como una correlación positiva con la severidad de la enfermedad. En este momento existen veinte padecimientos identificados que son causados exclusivamente por este tipo de mutación. Este trabajo es una breve revisión actualizada del tema.Unstable mutations, new challenges for genetic counseling of inherited disorders. Unstable mutations or amplification of DNA tandem repeats sequences constitute a new kind of genetic alteration discovered in the 90´s that cause hereditary diseases. This mutation has been found inside or near important

  5. Interpreting angina: symptoms along a gender continuum

    Science.gov (United States)

    Crea-Arsenio, Mary; Shannon, Harry S; Velianou, James L; Giacomini, Mita

    2016-01-01

    Background ‘Typical’ angina is often used to describe symptoms common among men, while ‘atypical’ angina is used to describe symptoms common among women, despite a higher prevalence of angina among women. This discrepancy is a source of controversy in cardiac care among women. Objectives To redefine angina by (1) qualitatively comparing angina symptoms and experiences in women and men and (2) to propose a more meaningful construct of angina that integrates a more gender-centred approach. Methods Patients were recruited between July and December 2010 from a tertiary cardiac care centre and interviewed immediately prior to their first angiogram. Symptoms were explored through in-depth semi-structured interviews, transcribed verbatim and analysed concurrently using a modified grounded theory approach. Angiographically significant disease was assessed at ≥70% stenosis of a major epicardial vessel. Results Among 31 total patients, 13 men and 14 women had angiograpically significant CAD. Patients describe angina symptoms according to 6 symptomatic subthemes that array along a ‘gender continuum’. Gender-specific symptoms are anchored at each end of the continuum. At the centre of the continuum, are a remarkably large number of symptoms commonly expressed by both men and women. Conclusions The ‘gender continuum’ offers new insights into angina experiences of angiography candidates. Notably, there is more overlap of shared experiences between men and women than conventionally thought. The gender continuum can help researchers and clinicians contextualise patient symptom reports, avoiding the conventional ‘typical’ versus ‘atypical’ distinction that can misrepresent gendered angina experiences. PMID:27158523

  6. Angina - what to ask your doctor

    Science.gov (United States)

    ... Below are some questions you may want to ask your health care provider to help you take ... What to ask your doctor about angina and heart disease; Coronary artery disease - what to ask your doctor

  7. Therapy for Stable Angina in Women

    OpenAIRE

    Sarbaziha, Raheleh; Sedlak, Tara; Shufelt, Chrisandra; Mehta, Puja K.; Merz, C. Noel Bairey

    2012-01-01

    Mortality rates for cardiovascular disease are higher in women than in men, but studies of women have been conducted less frequently. Current pharmacological and nonpharmacological treatment options for women with stable angina are reviewed.

  8. Bloqueo de Ganglio Estrellado en el tratamiento de angina de pecho refractaria: un posible tratamiento coadyuvante

    Directory of Open Access Journals (Sweden)

    Isaías Salas Herrera

    2002-04-01

    Full Text Available El presente trabajo corresponde una revisión bibliográfica de los estudios clínicos realizados en síndromes anginosos refractarios al tratamiento convencional, utilizando como tratamiento el bloqueo de ganglio estrellado. Se realizó una búsqueda de literatura publicada entre los años 1.900 al 2.000 en las bases de datos MDConsult, Medline y ProQuest. A su vez se revisaron las publicaciones en la Biblioteca del Hospital Rafael Ángel Calderón Guardia y en la Biblioteca del BINASSS (Biblioteca Nacional de Salud del Seguro Social. De acuerdo a los estudios analizados el bloqueo de ganglio estrellado se describe como posibilidad terapéutica para el control de dolor de la angina de pecho refractaria . La descripción clásica de la inervación cardíaca consiste en tres nervios simpáticos mayores originados de los ganglios cervicales superior, medio e inferior. Esta inervación simpática en conjunto con diversos nervios parasimpáticos, se describen como el plexo cardíaco. En contraste Jane et. al. (1986 en un estudio anatómico de 23 cadáveres describe que la inervación cardiopulmonar en el hombre se origina en el ganglio estrellado y las mitades caudales de las cadenas simpáticas cervicales junto con nervios que se originan del nervio recurrente laríngeo o del vago. De estas estructuras derivan los dos plexos cardiopulmonares. De estos plexos derivan tres nervios cardíacos mayores que se proyectan hacia el corazón. Se estima que determinado porcentaje de los pacientes diagnosticados con angina inestable progresará a desarrollar una angina refractaria al tratamiento. El bloqueo de ganglio estrellado podría ser un nuevo método terapéutico para controlar el dolor de dicha condición. Sin embargo se necesitan estudios clínicos randomizados a doble ciego para obtener resultados concluyentes.

  9. STUDY OF VARIABLES IN UNSTABLE ANGINA

    Directory of Open Access Journals (Sweden)

    Vijay Kumar

    2014-08-01

    Full Text Available OBJECTIVES: Prevalence rates of coronary artery disease are reported to be very high in Asian Indians. Traditional risk factors alone fail to explain the high rates of coronary disease in Indians. Acute phase reactants C-reactive protein in Indian subjects with unstable angina were evaluated and compare them with suitable control to test the hypothesis that a relationship exists between acute phase reactants and unstable angina. METHODOLOGY: 50 cases unstable angina and 50 suitable cases enrolled for the study. Unstable angina had significantly increased level of CRP compare to control group (p=0.01098.RESULTS: Statistically significant difference was found between case and control group in TLC (p=0.0037 and ESR (p=0.0368, TLC and ESR being more in case group as compare to control group. C- reactive protein was significantly correlated with TLC and ESR in case group and TLC and ESR in control group. C reactive protein, TLC and ESR in case group while no correlation was observed with any variable in control group. CONCLUSION: The present study concludes that a relationship exists between acute phase reactant studied and unstable angina

  10. CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA

    OpenAIRE

    A. Ya. Kravchenko; V. M. Provotorov

    2016-01-01

    Aim. To study efficacy of testosterone undecanoate (TU) therapy in men with stable angina and androgen deficiency.Material and methods. The serum testosterone level was detected in 247 men (aged 51,6±1,8 y.o.) with stable effort angina. 60 patients with androgen deficiency additionally to basic angina therapy received TU (120-160 mg daily). 54 patients with androgen deficiency (control group) received only basic angina therapy. Dynamics of clinical and ECG manifestations of myocardial ischemi...

  11. Utility of ranolazine in chronic stable angina patients

    OpenAIRE

    Patel, Pawan D; Arora, Rohit R

    2008-01-01

    Pawan D Patel, Rohit R AroraDepartment of Cardiology, Chicago Medical School, North Chicago, IL, USAAbstract: Chronic stable angina is a debilitating illness affecting at least 6.6 million US residents. Despite being optimally treated by pharmacotherapy and revascularization up to 26% of patients still experience angina. Diabetes mellitus is a common co-morbid condition in angina patients. Several new investigational medications are being tested for chronic angina. Advances in understanding o...

  12. Clinical Practice Guidelines for Unstable Angina Treatment.

    OpenAIRE

    Juan José Navarro López; Claudio Manuel González Rodríguez

    2009-01-01

    Clinical Practice Guidelines for Unstable Angina Treatment. It has been defined as the oppressive pain or uneasiness mainly thoracic, which is caused by a transitory myocardial ischemia. This document includes important aspects as classification, diagnosis, treatment (aimed at its principal strategies) and risk stratification. It includes assessment guidelines focused on the most important aspects to be accomplished.

  13. Angina - Multiple Languages: MedlinePlus

    Science.gov (United States)

    ... Chinese - Simplified (简体中文) Chinese - Traditional (繁體中文) French (français) Hindi (हिन्दी) Japanese (日本語) Korean (한국어) Portuguese (português) ... poitrine - français (French) Bilingual PDF Health Information Translations Hindi (हिन्दी) Angina हिन्दी (Hindi) Bilingual PDF ...

  14. Utility of ranolazine in chronic stable angina patients

    Directory of Open Access Journals (Sweden)

    Pawan D Patel

    2008-08-01

    Full Text Available Pawan D Patel, Rohit R AroraDepartment of Cardiology, Chicago Medical School, North Chicago, IL, USAAbstract: Chronic stable angina is a debilitating illness affecting at least 6.6 million US residents. Despite being optimally treated by pharmacotherapy and revascularization up to 26% of patients still experience angina. Diabetes mellitus is a common co-morbid condition in angina patients. Several new investigational medications are being tested for chronic angina. Advances in understanding of myocardial ischemia have prompted evaluation of a number of new antianginal strategies. In this review we discuss the utility of ranolazine, a recently approved novel antianginal agent and its efficacy in the diabetic patient population. In addition to its antianginal action in diabetic patients with chronic angina, ranolazine may have favorable effects on glycated hemoglobin levels.Keywords: chronic stable angina, antianginal, ranolazine, diabetes mellitus, glycated hemoglobin

  15. The economic burden of angina on households in South Asia

    OpenAIRE

    Alam, Khurshid; Mahal, Ajay

    2014-01-01

    Background Globally, an estimated 54 million people have angina, 16 million of whom are from the WHO South-East Asia region. Despite the increasing burden of cardiovascular disease (CVD) in South Asia, there is no evidence of an economic burden of angina on households in this region. We investigated the economic burden of angina on households in South Asia. Methods We applied a novel propensity score matching approach to assess the economic burden of angina on household out-of-pocket (OOP) he...

  16. Usefulness of hyperventilation myocardial SPECT for diagnosing vasospastic angina pectoris

    International Nuclear Information System (INIS)

    We evaluated the usefulness of hyperventilation myocardial scintigraphy (HV-SPECT) for diagnosing vasospastic angina pectoris. The subjects consisted of 11 patients with rest angina and 13 with rest and exertional angina in whom coronary spasm was demonstrated by coronary angiography, and 6 with exertional angina in whom a significant stenotic lesion was observed by coronary angiography. Hyperventilation was performed at a rate of 40/min for 5 minutes in all the patients. Ischemia was considered to be present when defect and redistribution were observed by SPECT. HV-SPECT revealed positive findings in 8 patients with rest angina (73%) and 9 with exertional and rest angina (69%) but only in 1 with exertional angina (17%). Ischemic ST changes on monitor ECG were observed in 13 of the 30 patients (43%); ST was enhanced in 4 patients and depressed in 9 patients. In the patients with rest angina, HV-SPECT induced ischemic findings more frequently than exercise SPECT (73% vs 55%). HV-SPECT seems to be useful as a non-invasive method for diagnosing angina pectoris resulting from coronary spasm. (author)

  17. costarricenses de primaria y secundaria

    Directory of Open Access Journals (Sweden)

    Julián Monge Nájera

    2006-01-01

    Full Text Available En Costa Rica, la informática dejó de ser una “nueva tecnología” para ser parte cotidiana de la vida de docentes y estudiantes. Sin embargo, el valor y tipo de uso de las computadoras y otros componentes de la informática en la enseñanza-aprendizaje aún son sujeto de debate entre los teóricos de la educación. La discusión se centra en un aspecto teórico y otro práctico. El teórico: ¿debe enseñarse cómo funciona la computadora o debe enseñarse simplemente a usarla? El práctico: ¿conviene usar la informática durante las lecciones, o sólo como un complemento extra-clase? Tras consultar a 231 mujeres y hombres dedicados a la enseñanza primaria y secundaria en toda Costa Rica, se encontró que la mayoría está a favor de cómo enseñar a usar la computadora (más que cómo funciona, tanto en el aula como fuera de ella. Sin embargo, en la vida real usan la informática más en actividades administrativas que educativas, y no han aprovechado el verdadero potencial de la tecnología de la información y comunicación (TIC en educación, por lo cual no han cosechado los logros que se esperan de su uso. Es urgente entonces un giro radical en la forma en que se apoya al personal docente y en cómo se emplean realmente las computadoras en la educación primaria y secundaria de Costa Rica.

  18. Preinfarction angina: old story initiates new attention

    Institute of Scientific and Technical Information of China (English)

    GE Jun-bo

    2012-01-01

    Since first report by Murry et al1 in 1986,the role of ischemia preconditioning before sustained coronary occlusion in protecting myocardium and reducing infarct size has been identified in animal studies.2-4 The mechanism underlying the endogenous cardioprotective effects of ischemia preconditioning is complex and may involve humoral,neural,or a combination of both,with different signaling pathwaysinvolving adenosine,bradykinin,protein kinases and K(ATP) channels.5,6 In humans,episodes of angina before acute myocardial infarction (AMI) may also confer a preconditioning or protective effect.

  19. Ludwig's angina after severe thrombocytopenic purpura associated with dengue fever

    Directory of Open Access Journals (Sweden)

    Maria Antonia Campos

    2014-01-01

    Full Text Available Here, we report a case of Ludwig's angina, which required surgery because of toothache. The patient had dengue and severe thrombocytopenia as confirmed by clinical and laboratory diagnoses. However, dengue is not included among the predisposing factors for Ludwig's angina.

  20. Comparación entre diferentes materiales inestables utilizados dentro del proceso de entrenamiento: Revisión Sistemática

    OpenAIRE

    Bustamante Aranguren, Paula

    2014-01-01

    RESUMEN: Introducción: la popularidad de los entrenamientos realizados en superficies inestables para mejorar el rendimiento deportivo ha ido creciendo en los últimos años. El objetivo de esta revisión fue conocer la efectividad de los ejercicios realizados en inestabilidad durante los entrenamientos deportivos. Métodos: se realizó una búsqueda bibliográfica sobre el tema en bases electrónicas de datos: Medline, PubMed, PEDro, Elsevier, Cochrane Library y Google Académico,mediante las pala...

  1. Comparative study of left ventricular function in patients with unstable angina, non-Q wave myocardial infarction and stable angina pectoris: assessment with atrial pacing and digital ventriculography.

    Science.gov (United States)

    Hussain, K M; Gould, L; Pomerantsev, E V; Angirekula, M; Bharathan, T

    1995-10-01

    To compare left ventricular global and segmental function at rest and during right atrial pacing in patients with unstable angina, non-Q wave myocardial infarction, and stable angina (class III angina), low-dose digital subtraction ventriculography was performed at rest and after abrupt cessation of pacing in 42 patients with unstable angina, 8 patients with non-Q wave myocardial infarction and 15 patients with stable angina during selective coronary arteriography. Left ventricular ejection fraction was significantly lower at rest in patients with unstable angina (P < 0.01) and non-Q wave myocardial infarction (P < 0.05) and during pacing (P < 0.01). These two groups of patients had significantly higher values of left ventricular end-diastolic and end-systolic volumes at rest and during pacing as compared with stable angina group. In comparing various clinical patterns of unstable angina, ejection fraction was significantly (P < 0.05) lower during pacing in patients with crescendo angina than in new-onset angina. However, ejection fraction was significantly (P < 0.01) lower in crescendo angina only at rest as compared with rest angina. The length of zone of severe hypokinesia was greater in unstable angina (P < 0.01) as well as in non-Q wave myocardial infarction (P < 0.05) both at rest and during pacing as compared with stable angina. Contractility of region of hypokinesia during pacing was higher (P < 0.01) in stable angina than in unstable angina and non-Q wave myocardial infarction. In analyzing segmental function in various subgroups of unstable angina, the authors found that the length of total hypokinesia was significantly higher (P < 0.05) during pacing in crescendo angina than in new-onset angina. Contractility of region of hypokinesia was lowest at rest and during pacing in patients with crescendo angina. This study demonstrates that patients with unstable angina as well as non-Q wave myocardial infarction were characterized by more pronounced global and

  2. Mediastinite descendente necrosante pós-angina de Ludwig Necrotizing descending mediastinitis afetr Ludwig angina

    Directory of Open Access Journals (Sweden)

    MARICÉLIA BROMMELSTROET

    2001-09-01

    Full Text Available A angina de Ludwig é uma infecção do espaço submandibular originada, em geral, da infecção do 2º ou 3º molar inferior. Como conseqüência, pode causar mediastinite descendente necrosante, que representa uma forma grave e rara de infecção mediastinal, a qual exige diagnóstico precoce e tratamento cirúrgico para reduzir a alta mortalidade associada a esta doença. Dois casos de mediastinite descendente necrosante pós-angina de Ludwig foram tratados com excelentes resultados em nosso hospital. A drenagem mediastinal transcervical está justificada em pacientes com doença limitada ao mediastino superior. Porém, sepse com comprometimento extenso do mediastino requer drenagem através de toracotomia sem demora.Ludwig's angina is an infection of the submandibular space generally caused by an infection of the 2nd or 3rd lower molar. As a consequence, descending necrotizing mediastinitis, a rare and severe form of mediastinal infection, may occur. The descending necrotizing mediastinitis represents a rare form of mediastinal infection. It presents a high mortality and to decrease that rate it is necessary prompt diagnosis and surgical treatment. Two cases of descending necrotizing mediastinitis due to Ludwig's angina were treated with excellent results in our hospital. The transcervical mediastinal drainage is justified in patients with disease limited to the upper mediastinum. Even so, when there is extensive involvement of the whole mediastinum it is suitable the accomplishment of a wide thoracotomy.

  3. Angina bullosa hemorrhagica: report of 11 cases

    Directory of Open Access Journals (Sweden)

    Julieta Ruiz Beguerie

    2014-05-01

    Full Text Available Angina bullosa hemorrhagica is a rare and benign disorder, usually localized in the subepithelial layer of the oral, pharyngeal and esophageal mucosa. The lesions are characterized by their sudden onset. They appear as a painless, tense, dark red and blood-filled blister in the mouth that rapidly expand and rupture spontaneously in 24-48 hours. The underlying etiopathology remains ill defined, although it may be a multifactorial phenomenon including diabetes, and steroid inhalers. The condition is not attributable to blood dyscrasias, nor other vesicular-bullous disorders. In this study, eleven patients with such blisters are described. Physical examination of the patients revealed a single blister with hemorrhagic content localized in the oral mucosa. Biopsy of the lesions showed sub epithelial blisters with a mild infiltrate. In general practice, dermatologists could face a blood-filled bullous lesion of the oral mucosa. Recognition is, therefore, of great importance for dermatologists.

  4. Physical Activitiea Associted with Angina Pectoris Before Myocardial Infarction and the Onset of Myocardial Infarction

    OpenAIRE

    Matsuda, Masako

    1984-01-01

    One hundred and ninety-seven patients with a history of myocardeal infarction were interviewed to evaluate the incidence of angina pectoris and the physical activity precipitating angina before myocardial infarction, and the mode of physical activity at the onset of myocardial infarction. Ninety-ewo patients had no angina before infarction, whereas 105 did, In 105 patients, 58 had a chronic stable angina without a change of pattern of angina before infarction, while 22 noticed worsening of th...

  5. Long-term effects of spinal cord stimulation on angina symptoms and quality of life in patients with refractory angina pectoris--results from the European Angina Registry Link Study (EARL)

    DEFF Research Database (Denmark)

    Andréll, P; Yu, W; Gersbach, P; Gillberg, L; Pehrsson, K; Hardy, I; Ståhle, A; Andersen, Claus; Mannheimer, C

    2010-01-01

    To assess the long-term effect of spinal cord stimulation (SCS) on angina symptoms and quality of life in patients with refractory angina pectoris defined as severe angina due to coronary artery disease resistant to conventional pharmacological therapy and/or revascularisation....

  6. Diseño y control de un sistema electromecánico inestable de dos grados de libertad: aplicación al caso de un péndulo invertido

    OpenAIRE

    Molis Merino, Eugenio

    2015-01-01

    En este proyecto, se ha realizado el diseño y el control de un sistema electromecánico inestable de dos grados de libertad. Aplicación al caso de un péndulo invertido, un sistema no lineal e inestable controlado mediante un microcontrolador para la etapa de control, un giroscopio para la lectura de datos para su posterior procesamiento y control y un driver para la etapa de potencia. Para el diseño del controlador y la obtención de los diferentes parámetros de ajuste ha sido...

  7. Ecuador: una democracia inestable

    OpenAIRE

    Juan J. Paz y Miño Cepeda

    2009-01-01

    En 1979, tras una década de dictaduras militares, se inició la fase constitucional más larga en la historia del Ecuador. Ésta se levantó sobre las herencias del pasado y se caracterizó, de manera fundamental, por el tránsito desde un modelo estatal-desarrollista hacia uno de tipo empresarial, por el aparecimiento de nuevos agentes sociales, el multipartidismo político, la regionalización nacional, la presencia multicultural y la inserción del país en nuevas relaciones internacionales. Pero es...

  8. Neurostimulation bei refraktärer Angina pectoris

    Directory of Open Access Journals (Sweden)

    Theres H

    2005-01-01

    Full Text Available Trotz großer Fortschritte der katheterinterventionellen und operativen Versorgung der koronaren Herzkrankheit (KHK verbleiben Patienten, bei denen eine Revaskularisierung nicht möglich ist. Besteht eine ausgeprägte Angina pectoris (CCS III–IV, so sprechen wir von einer "refraktären Angina pectoris". Eine Arbeitsgruppe der Europäischen Gesellschaft für Kardiologie führt die Neurostimulation an erster Stelle der alternativen Therapiemöglichkeiten für diese Patienten an. Zahlreiche Studien belegen, daß es sich dabei um eine effiziente und sichere adjuvante Therapie handelt. Sie führt zu einer Abnahme der Angina pectoris-Symptomatik mit konsekutiver Zunahme der körperlichen Leistungsfähigkeit. Ingesamt wird eine entscheidende Verbesserung der Lebensqualität erzielt, die Angina pectoris als Warnsymptom bei Myokardinfarkt wird jedoch nicht maskiert.

  9. Observations on the warm up phenomenon in angina pectoris.

    OpenAIRE

    Joy, M; Cairns, A W; Sprigings, D

    1987-01-01

    Adaptation to exercise was investigated in 14 men aged 34-69 years (mean 51) with stable exertional angina caused by occlusive coronary artery disease. All underwent exercise electrocardiography to symptom limitation according to the Bruce protocol (first effort), and exercise to the onset of angina (warm up) followed by four minutes' rest, followed by exercise to symptom limitation (second effort). This protocol was repeated after sequential treatment for one month each with nifedipine 10 mg...

  10. NEBIVOLOL IN TREATMENT OF STABLE EXERTIONAL ANGINA PECTORIS

    OpenAIRE

    Gavrilov, Y V; V. A. Sulimov; V. I. Makolkin

    2015-01-01

    Aim. To evaluate antianginal and antiischemic efficiency of nebivolol in patients with stable angina pectoris.Material and methods. 100 patients with ischemic heart disease showing stable exertional angina pectoris and having no contraindications to beta-blockers were studied. After 5-7 days of control period 50 randomly selected patients began to take nebivolol in initial dose of 5mg once daily and 50 patients started to take metoprolol in initial dose of 50 mg twice daily. Duration of treat...

  11. Emerging clinical role of ranolazine in the management of angina

    OpenAIRE

    Vadnais, David S; Wenger, Nanette K.

    2010-01-01

    David S Vadnais, Nanette K WengerDivision of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USAAbstract: Chronic stable angina is an exceedingly prevalent condition with tremendous clinical, social, and financial implications. Traditional medical therapy for angina consists of beta-blockers, calcium channel blockers, and nitrates. These agents decrease myocardial oxygen demand and ischemia by reducing heart rate, lowering blood pressure, and/or optimizing ventricular loadi...

  12. CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA

    Directory of Open Access Journals (Sweden)

    A. Ya. Kravchenko

    2016-01-01

    Full Text Available Aim. To study efficacy of testosterone undecanoate (TU therapy in men with stable angina and androgen deficiency.Material and methods. The serum testosterone level was detected in 247 men (aged 51,6±1,8 y.o. with stable effort angina. 60 patients with androgen deficiency additionally to basic angina therapy received TU (120-160 mg daily. 54 patients with androgen deficiency (control group received only basic angina therapy. Dynamics of clinical and ECG manifestations of myocardial ischemia and quality of life (QOL parameters was studied.Results. Androgen deficiency is revealed in 114 (46,2% of patients. Therapy with TU during 3 months resulted in reduction of angina attacks and extent of myocardial ischemia (according to Holter ECG monitoring and stress test as well as QOL improvement.Conclusion. Androgen deficiency is observed in 46,2% of men with stable angina. TU increases of antianginal therapy efficacy, improves QOL and is well tolerated. 

  13. Ranolazine Reduces Patient-Reported Angina Severity and Frequency and Improves Quality of Life in Selected Patients with Chronic Angina

    OpenAIRE

    Muhlestein, Joseph B.; Grehan, Sharon

    2013-01-01

    Background Chronic stable angina negatively affects quality of life (QoL). American College of Cardiology/American Heart Association guidelines highlight maintaining/restoring a level of activity, functional capacity, and QoL that is satisfactory to the patient as an objective of treatment, and further define the treatment goal for most patients as maximizing survival and achieving prompt and complete (or near-complete) elimination of angina with a return to normal activities. Objective To as...

  14. Monitorización de laderas inestables mediante técnicas fotogramétricas a partir de vuelos UAV e históricos

    OpenAIRE

    Fernández, Tomás; Pérez, José Luis; López, Andrés; Gómez, José Miguel; Cardenal, Javier; Delgado, Jorge

    2014-01-01

    Este trabajo presenta una metodología para la monitorización de laderas inestables mediante técnicas fotogramétricas, partiendo de vuelos UAV de muy alta resolución. Para ello se han realizado y analizado cuatro campañas de UAV desde noviembre de 2012 en una zona situada en las inmediaciones de la Guardia (Jaén), y además se ha utilizado un vuelo fotogramétrico previo de la misma zona. Los vuelos UAV se han realizado mediante una plataforma aérea ligera de tipo helicóptero o drone –provisto d...

  15. Functional Role of Dendritic Cells in Patients with Unstable Angina

    Institute of Scientific and Technical Information of China (English)

    LI Dazhu; Sharma Ranjit; ZENG Qiutang

    2005-01-01

    To investigate the function of dendritic cells (DC) in patients with unstable angina, 10 mL of blood was drawn from 30 subjects. 15 patients diagnosed as having unstable angina and 15 healthy subjects were included in an observation and a control groups respectively. The mononuclear cells were separated from the peripheral blood and cultured in RPMI1640 supplemented with recombinant human granulocyte/macrophage-colony stimulating factor (rh GM-CSF) and recombinant human interleukin-4 (rh IL-4) to induce dendritic cells. The shape and ultrastructure of DC was examined with electronic microscope. The phenotype of DC was analyzed with FACS and the alloantigen presenting capacity of DC was evaluated by mixed lymphocyte reaction (MLR). The expression rate of CD86 of DC in patients with unstable angina was (40.7±3.6) %, which was obviously higher than that of normal DC (29.6±2.5 %) (P<0.001). The capacity of the DCs in unstable angina patients to induce allogenic T cells (OD 2.73±1.10), was significantly higher than that of the normal DC (OD:0.9±0.21) (P<0.005). It is suggested that the function of DC in patients with unstable angina is increased, which may play an important role in the initiation of immune reaction in the plaque.

  16. Osteodistrofia de la cirrosis biliar primaria

    OpenAIRE

    Guañabens Gay, Nuria

    1987-01-01

    [spa] La cirrosis biliar primaria es una enfermedad hepática que se manifiesta por un patrón clínico, bioquímico e histológico de colestasis crónica. Su curso puede complicarse con el desarrollo de una patología metabólica ósea cuyo tipo, frecuencia y mecanismos patogenéticos no están bien establecidos. Esta tesis se ha realizado con el fin de analizar la prevalencia y tipo de enfermedad metabólica ósea que se asocia a la cirrosis biliar primaria (CBP) e investigar los factores que influy...

  17. Unstable angina of crescendo pattern vs new onset: a clinical, coronary arteriographic and hemodynamic study.

    Science.gov (United States)

    Hussain, K M; Gould, L; Bharathan, T; Abdelsayed, G; Karpov, Y

    1995-06-01

    Unstable angina includes a variety of clinical presentations with a different level of risk for an unfavorable outcome. In this study the authors investigated the prognostic significance of crescendo angina and new-onset angina to discuss management strategies, paying attention to the relevance of baseline clinical characteristics, coronary artery lesions, and left ventricular function, as well as their alterations during atrial pacing. Accordingly coronary arteriographic anatomy and changes in left ventricular volumes and ejection fraction before and during atrial pacing were studied by means of digital subtraction ventriculography in 18 patients with crescendo angina and in 18 patients with new-onset angina. Triple-vessel disease was more frequently observed in crescendo angina (56%; P < 0.05) as compared with the patients with new-onset angina (11%). Complex coronary morphology was statistically more likely to be found in crescendo angina. The angiographic evidence of intracoronary thrombi was found in 33% (P < 0.05) patients with crescendo angina and in 4% patients with new-onset angina. Compared with the patients with new-onset angina, patients with crescendo angina had higher end-diastolic and end-systolic volumes and lower ejection fraction at rest. At peak pacing, ejection fraction was significantly (P < 0.05) lower in crescendo angina (0.48 +/- 0.06) than in new-onset angina (0.66 +/- 0.04). In crescendo angina, during pacing, the magnitude of velocity of circumferential fiber shortening was significantly decreased as compared with new-onset angina.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7785791

  18. Circulating fibrocytes as predictors of adverse events in unstable angina.

    Science.gov (United States)

    Keeley, Ellen C; Schutt, Robert C; Marinescu, Mark A; Burdick, Marie D; Strieter, Robert M; Mehrad, Borna

    2016-06-01

    Half of the patients who present with unstable angina (UA) develop recurrent symptoms over the subsequent year. Identification of patients destined to develop such adverse events would be clinically valuable, but current tools do not allow for this discrimination. Fibrocytes are bone marrow-derived progenitor cells that co-express markers of leukocytes and fibroblasts and are released into the circulation in the context of tissue injury. We hypothesized that, in patients with UA, the number of circulating fibrocytes predicts subsequent adverse events. We enrolled 55 subjects with UA, 18 with chronic stable angina, and 22 controls and correlated their concentration of circulating fibrocytes to clinical events (recurrent angina, myocardial infarction, revascularization, or death) over the subsequent year. Subjects with UA had a >2-fold higher median concentration of both total and activated fibrocytes compared with subjects with chronic stable angina and controls. In UA subjects, the concentration of total fibrocytes identified those who developed recurrent angina requiring revascularization (time-dependent area under the curve 0.85) and was superior to risk stratification using thrombolysis in myocardial infarction risk score and N-terminal pro B-type natriuretic peptide levels (area under the curve, 0.53 and 0.56, respectively, P fibrocyte level was associated with recurrent angina (hazard ratio, 1.016 per 10,000 cells/mL increase; 95% confidence interval, 1.007-1.024; P fibrocytes are elevated in patients with UA and successfully risk stratify them for adverse clinical outcomes. Fibrocytes may represent a novel biomarker of outcome in this population. PMID:27012475

  19. Significance of Tc-99m pyrophosphate accumulation in unstable angina

    International Nuclear Information System (INIS)

    Tc-99m pyrophosphate (PYP) and Tl-201 simultaneous dual energy single photon emission computed tomography (SPECT) were performed in 33 patients with clinically unstable angina. According to the presence or absence of PYP accumulation in the myocardium, the patients were classified as PYP (+) group (n=22) and PYP (-) group (n=11). Clinical features, types of unstable angina, ECG changes, and serial creatine kinase (CK) data were compared in the two groups. The 'new angina at rest' type of unstable angina was more significantly common in the PYP (+) group (16/22) than the PYP (-) group (2/11). The remaining 6 patients in the PYP (+) group and 2 patients in the PYP (-) group had 'angina of effort with changing pattern'. There was a significant difference in the occurrence of ST elevation and ST depression between the group: 59% in the PYP (+) group vs. 18% in the PYP (-) group for ST elevation and 23% in the PYP (+) group vs. 64% in the PYP (-) group for ST depression. The PYP (+) group showed significant improvement in ejection fraction in the stable state (57±12%) as compared with the unstable state (62±11%), although there was no difference between the stable and unstable state in the PYP (-) group. Although wall motion abnormality index (WMI) was poorer in the PYP (+) group than the PYP (-) group, it improved to the same degree as the PYP (-) group one month later. These data suggest that the area showing PYP (+) may reflect stunned myocardium and that Tc-99m PYP accumulation may correlate with clinical features of unstable angina. (N.K.)

  20. Reduced peripheral vascular reactivity in refractory angina pectoris

    DEFF Research Database (Denmark)

    Bondesson, Susanne M; Edvinsson, Marie-Louise; Pettersson, Thomas;

    2011-01-01

    compared to matched healthy subjects (n = 20). The cutaneous forearm microvascular blood flow was measured by Laser-Doppler flowmetry. The vascular responsiveness to iontophoretic administration of acetylcholine (ACh), sodium nitroprusside (SNP) and local skin warming were studied. Measurements of Canadian......AIMS: To examine if the skin microvascular bed is altered and can be modified by enhanced external counterpulsation (EECP) in patients with chronic refractory angina. METHODS: Twenty patients diagnosed with refractory angina were divided into EECP (n = 10) or no EECP (n = 10) groups. The data were...

  1. Neurostimulation bei refraktärer Angina pectoris

    OpenAIRE

    Theres H; Baumann G; Eddicks S; Maier-Hauff K; Schenk M.; Spies C

    2005-01-01

    Trotz großer Fortschritte der katheterinterventionellen und operativen Versorgung der koronaren Herzkrankheit (KHK) verbleiben Patienten, bei denen eine Revaskularisierung nicht möglich ist. Besteht eine ausgeprägte Angina pectoris (CCS IIIIV), so sprechen wir von einer "refraktären Angina pectoris". Eine Arbeitsgruppe der Europäischen Gesellschaft für Kardiologie führt die Neurostimulation an erster Stelle der alternativen Therapiemöglichkeiten für diese Patienten an. Zahlreiche Studien b...

  2. Combination treatment with trimetazidine and diltiazem in stable angina pectoris

    OpenAIRE

    Manchanda, S; Krishnaswami, S

    1997-01-01

    Objective—To assess antianginal efficacy and possible adverse haemodynamic effects of combination treatment with trimetazidine and diltiazem in patients with stable angina.
Design—Double blind, randomised, placebo controlled trial of four weeks duration.
Setting—Outpatient department of two Indian hospitals.
Subjects—64 male patients with stable angina, uncontrolled on diltiazem alone.
Interventions—Diltiazem 180 mg and trimetazidine 60 mg, or diltiazem 180 mg and placebo daily.
Main outcome ...

  3. NEBIVOLOL IN TREATMENT OF STABLE EXERTIONAL ANGINA PECTORIS

    Directory of Open Access Journals (Sweden)

    Y. V. Gavrilov

    2015-12-01

    Full Text Available Aim. To evaluate antianginal and antiischemic efficiency of nebivolol in patients with stable angina pectoris.Material and methods. 100 patients with ischemic heart disease showing stable exertional angina pectoris and having no contraindications to beta-blockers were studied. After 5-7 days of control period 50 randomly selected patients began to take nebivolol in initial dose of 5mg once daily and 50 patients started to take metoprolol in initial dose of 50 mg twice daily. Duration of treatment was 8 weeks. Efficiency of treatment was assessed according to the results of control treadmill assessment and control daily ECG monitoring.Results. 56-day therapy with nebivolol at a dose of 7,5 mg per day results in increase in duration of treadmill test before angina or ST depression (p<0.05. Antianginal and antiischemic effect of nebivolol 7.5 mg once daily is rather similar with that of metoprolol in average daily dose of 175 mg. Nebivolol compared to metoprolol significantly (p<0.05 more effectively reduces the number of silent myocardial ischemia.Conclusion. Nebivolol is an efficient antianginal and antiischemic drug for patients with stable exertional angina pectoris.

  4. Capecitabine cardiac toxicity presenting as effort angina: a case report.

    Science.gov (United States)

    Lestuzzi, Chiara; Crivellari, Diana; Rigo, Fausto; Viel, Elda; Meneguzzo, Nereo

    2010-09-01

    We report a case of capecitabine-induced cardiotoxicity (effort angina) in a woman with metastatic breast carcinoma. Due to cancer progression, rechallenge of therapy with capecitabine was attempted, using several strategies in order to prevent cardiotoxicity. The most (even if not fully) effective strategy was reducing capecitabine dosage together with nitrates, calcium-channel blockers and trimetazidine therapy. PMID:20093950

  5. Transluminal angioplasty in the management of mesenteric angina

    International Nuclear Information System (INIS)

    The efficacy of transluminal angioplasty for the treatment of peripheral atherosclerotic disease has been well documented. The successful treatment of abdominal angina has been reported, although the follow-up is too short to accurately evaluate the long term results of this procedure. (orig.)

  6. Management Options in Chronic Stable Angina Pectoris: Focus on Ranolazine

    OpenAIRE

    Vadnais, David S; Wenger, Nanette K.

    2009-01-01

    Chronic stable angina pectoris results from a fixed coronary arterial obstruction causing an imbalance between myocardial oxygen supply and demand. Current therapy aims to reduce cardiovascular events (vasculoprotective) thereby improving survival, and/or relieve ischemic symptoms (antianginal) thereby improving the quality of life. Vasculoprotective therapy consists of lifestyle modification, antiplatelet agents, lipid lowering therapy and angiotensin-converting enzyme (ACE) inhibitors. Conv...

  7. Ranolazin--ny behandling af kronisk stabil angina pectoris

    DEFF Research Database (Denmark)

    Ahlehoff, Ole; Hansen, Peter Riis

    2009-01-01

    Ranolazine sustained-release tablets were recently approved in the EU for chronic stable angina as add-on therapy when symptoms are not controlled with first-line agents. The mechanism of action is thought to involve inhibition of late sodium influx in the heart, which can reduce abnormalities...

  8. Emerging clinical role of ranolazine in the management of angina

    Directory of Open Access Journals (Sweden)

    David S Vadnais

    2010-10-01

    Full Text Available David S Vadnais, Nanette K WengerDivision of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USAAbstract: Chronic stable angina is an exceedingly prevalent condition with tremendous clinical, social, and financial implications. Traditional medical therapy for angina consists of beta-blockers, calcium channel blockers, and nitrates. These agents decrease myocardial oxygen demand and ischemia by reducing heart rate, lowering blood pressure, and/or optimizing ventricular loading characteristics. Unique in its mechanism of action, ranolazine is the first new antianginal agent approved for use in the US for chronic angina in over 25 years. By inhibiting the late inward sodium current (INa, ranolazine prevents pathologic intracellular calcium accumulation that leads to ischemia, myocardial dysfunction, and electrical instability. Ranolazine has been proven in multiple clinical trials to reduce the symptoms of angina safely and effectively and to improve exercise tolerance in patients with symptomatic coronary heart disease. These benefits occur without reduction in heart rate and blood pressure or increased mortality. Although ranolazine prolongs the QTc, experimental data indicate that ranolazine may actually be antiarrhythmic. In a large acute coronary syndrome clinical trial, ranolazine reduced the incidence of supraventricular tachycardia, ventricular tachycardia, new-onset atrial fibrillation, and bradycardic events. Additional benefits of ranolazine under investigation include reductions in glycosylated hemoglobin levels and improved left ventricular function. Ranolazine is a proven antianginal medication in patients with symptomatic coronary heart disease, and should be considered as an initial antianginal agent for those with hypotension or bradycardia.Keywords: chronic angina, myocardial ischemia, ranolazine, pharmacotherapy, antianginal, sodium current

  9. Danza en Educación Primaria

    OpenAIRE

    Pedrero Muñoz, Concepción

    2013-01-01

    La danza introducida por una breve reseña en educación nos lleva a un estudio de su situación actual en el sistema educativo. La danza en Educación Primaria como aprovechamiento didáctico y recurso educativo, hace posible incorporar el término de Danza histórica (las primeras danzas escritas por los Maestros de danza) en el planteamiento de competencias introducido en el currículo escolar. Expresamos diversos aspectos para la configuración didáctica de la danz...

  10. El ciberbullying en las aulas de primaria

    OpenAIRE

    Teja Solana, Guillermo

    2014-01-01

    Resumen El surgimiento de las redes sociales ha dado lugar a un cambio en el modo en que los niños se relacionan entre sí y con el mundo. Desde entonces, el bullying ha adoptado nuevas formas. En el presente trabajo, nos centraremos en diversos aspectos del ciberbullying, principalmente desde una perspectiva teórica. Se presta especial atención a su incidencia y prevalencia en las aulas de educación primaria. Estas directrices proporcionan las bases para la prevención de factores de riesgo y ...

  11. Persistent angina: highly prevalent and associated with long-term anxiety, depression, low physical functioning, and quality of life in stable angina pectoris

    DEFF Research Database (Denmark)

    Jespersen, L.; Abildstrom, S. Z.; Hvelplund, Anders;

    2013-01-01

    To evaluate persistent angina in stable angina pectoris with no obstructive coronary artery disease (CAD) compared to obstructive CAD and its relation to long-term anxiety, depression, quality of life (QOL), and physical functioning. We invited 357 patients (men = 191; women = 166; response rate 83...... %) with no prior cardiovascular disease who had a first-time coronary angiography (CAG) in 2008-2009 due to suspected stable angina to participate in a questionnaire survey in 2011 with the Seattle Angina Questionnaire and the Hospital Anxiety and Depression Scale as key elements. Long-term persistent...... angina (i.e., symptoms at least once a month) was present in 64 % of patients with diffuse non-obstructive CAD (1-49 % stenosis), 49 % of patients with normal coronary arteries (0 % stenosis), and 41 % of patients with obstructive CAD (a parts per thousand yen50 % stenosis) (P = 0.01). Depression and...

  12. 'Variant' angina: Evidence for small vessel coronary artery spasm

    International Nuclear Information System (INIS)

    A unique case of 'variant' angina pectoris has been observed in a patient with normal coronary arteries and typical chest pain appearing spontaneously at rest, and repeatedly provoked by ergonovine maleate (0.1 mg iv) associated with large transmural perfusion defects on 201TI-imaging (after ergonovine) and a marked increase in T wave voltage despite no demonstrable spasm of a major coronary artery after the same doses of ergonovine. While saline solution could not provoke chest pain and treatment with a beta-blocking agent increased the frequency of ischemic attacks, a calcium antangonist therapy reduced and eventually eliminated the attacks. Thus, this case provides evidence for yet another aspect of a 'variant' form of angina pectoris: small vessel coronary artery spasm. (orig.)

  13. Anipamil prevents ST depression in patients with stable angina pectoris

    DEFF Research Database (Denmark)

    Larsen, C T; Sørum, C; Rasmussen, V; Fischer Hansen, J

    1993-01-01

    patients received anipamil 80 mg once daily, anipamil 160 mg once daily, and placebo in a randomized order. At the end of each treatment period the patients underwent 24-hour ambulatory ECG recording. Nineteen patients were included, all with typical stable angina pectoris for at least 2 months, exercise......The purpose of this study was to examine the 24-hour antiischemic efficacy of once-a-day anipamil compared to placebo in the treatment of patients with stable angina. The study was designed as a double-blind, placebo-controlled crossover study with an initial 3 week single-blind placebo period. The...... once a day is an effective 24-hour antiischemic drug in the treatment of transient myocardial ischemia....

  14. Thoracic empyema resulting from direct extension of Ludwig's angina

    OpenAIRE

    Youssef, M

    2016-01-01

    A 17-year-old Egyptian male developed Ludwig's angina after a failed trial of treatment a left lower teeth abscess, which was complicated by LT sided empyema and pneumonia. Assessment/Results: The patient arrived at ER dep. .Intraoral examination showed moderate trismus, fetid odor. There was bilateral sublingual edema (left > right) and an ulceration in the left floor of the mouth that was spontaneously draining purulent fluid. No cardiac murmurs or rubs were evident.Initial diagnostic labor...

  15. Myocardial bridge: The cause of angina in a young man

    OpenAIRE

    Vijayvergiya, Rajesh; Mittal, Bhagwant Rai

    2013-01-01

    Myocardial bridging is basically the systolic narrowing of epicardial coronary arteries, secondary to their tunneled course in myocardium. Though it is a benign condition it can have the symptoms like acute coronary syndrome, arrhythmias and sudden cardiac death. We report a 32-year-old male, who presented with typical exertional angina, had positive exercise treadmill and thallium-201 test. Coronary angiography revealed myocardial bridge of distal left anterior descending coronary artery. He...

  16. Epidural spinal electrical stimulation in severe angina pectoris.

    OpenAIRE

    Mannheimer, C; Augustinsson, L E; Carlsson, C A; Manhem, K; Wilhelmsson, C

    1988-01-01

    The short term effects of epidural spinal electrical stimulation were studied in 10 patients with angina pectoris of New York Heart Association functional class III or IV. The antianginal pharmacological treatment given at entry to the study was regarded as optimal and was not changed during the study. The effects of epidural spinal electrical stimulation were measured by repeated bicycle ergometer tests. Treatment with epidural spinal electrical stimulation increased the patients' working ca...

  17. Management Options in Chronic Stable Angina Pectoris: Focus on Ranolazine

    Directory of Open Access Journals (Sweden)

    David S. Vadnais

    2009-01-01

    Full Text Available Chronic stable angina pectoris results from a fixed coronary arterial obstruction causing an imbalance between myocardial oxygen supply and demand. Current therapy aims to reduce cardiovascular events (vasculoprotective thereby improving survival, and/or relieve ischemic symptoms (antianginal thereby improving the quality of life. Vasculoprotective therapy consists of lifestyle modification, antiplatelet agents, lipid lowering therapy and angiotensin-converting enzyme (ACE inhibitors. Conventional antianginal therapy for patients with chronic stable angina consists of beta-blockers, calcium channel blockers and nitrates, with surgical or percutaneous revascularization serving an adjunctive role. Despite the investigation of multiple novel therapies and medications over the past 25 years, arguably the most significant contribution to antianginal therapy during that time involved the recent introduction of ranolazine. Ranolazine acts via a distinctive pathway, inhibiting the late sodium current of the action potential in ischemic myocytes. Multiple studies have demonstrated that ranolazine significantly reduces anginal symptoms and improves exercise performance in patients with chronic stable angina but does not reduce mortality. Ranolazine does not affect either heart rate or blood pressure, a unique property among the current antianginal agents. Despite its QT prolongation, ranolazine has a proven safety profile and is not proarrhythmic. In fact, in a recent large randomized trial, ranolazine reduced the incidence of supraventricular tachycardia, ventricular tachycardia, new-onset atrial fibrillation and bradycardic events. Ranolazine may confer some additional benefits such as a reduction in HbA1c levels and improved left ventricular diastolic function. Ranolazine is now approved for use in chronic stable angina. Current guidelines recommend beta-blockers as the first line antianginal agent due to the proven mortality reduction. However, for

  18. Update on ranolazine in the management of angina

    OpenAIRE

    Codolosa JN; Acharjee S; Figueredo VM

    2014-01-01

    J Nicolás Codolosa,1 Subroto Acharjee,1 Vincent M Figueredo1,2 1Einstein Center for Heart and Vascular Health, Einstein Medical Center, 2Jefferson Medical College, Philadelphia, PA, USA Abstract: Mortality rates attributable to coronary heart disease have declined in recent years, possibly related to changes in clinical presentation patterns and use of proven secondary prevention strategies. Chronic stable angina (CSA) remains prevalent, and the goal of treatment is control of symptom...

  19. Update on ranolazine in the management of angina

    Directory of Open Access Journals (Sweden)

    Codolosa JN

    2014-06-01

    Full Text Available J Nicolás Codolosa,1 Subroto Acharjee,1 Vincent M Figueredo1,2 1Einstein Center for Heart and Vascular Health, Einstein Medical Center, 2Jefferson Medical College, Philadelphia, PA, USA Abstract: Mortality rates attributable to coronary heart disease have declined in recent years, possibly related to changes in clinical presentation patterns and use of proven secondary prevention strategies. Chronic stable angina (CSA remains prevalent, and the goal of treatment is control of symptoms and reduction in cardiovascular events. Ranolazine is a selective inhibitor of the late sodium current in myocytes with anti-ischemic and metabolic properties. It was approved by the US Food and Drug Administration in 2006 for use in patients with CSA. Multiple, randomized, placebo-controlled trials have shown that ranolazine improves functional capacity and decreases anginal episodes in CSA patients, despite a lack of a significant hemodynamic effect. Ranolazine did not improve cardiovascular mortality or affect incidence of myocardial infarction in the MERLIN (Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-TIMI (Thrombolysis In Myocardial Infarction 36 trial, but significantly decreased the incidence of recurrent angina. More recently, ranolazine has been shown to have beneficial and potent antiarrhythmic effects, both on supraventricular and ventricular tachyarrhythmias, largely due to its inhibition of the late sodium current. Randomized controlled trials testing these effects are underway. Lastly, ranolazine appears to be cost-effective due to its ability to decrease angina-related hospitalizations and improve quality of life. Keywords: ranolazine, chronic stable angina, coronary artery disease

  20. Plasma resistin is increased in patients with unstable angina

    Institute of Scientific and Technical Information of China (English)

    HU Wen-lan; QIAO Shu-bin; HOU Qing; YUAN Jian-song

    2007-01-01

    Background Resistin, a novel adipokine linked to insulin resistance and obesity in rodents, which is derived mainly from macrophages and identified in atheromas in human, has been shown to play a potential role in atherosclerosis.Resistin levels were reported to increase in coronary artery disease (CAD), while data concerning resistin in different stages of CAD in Chinese people are lacking. The aim of this study was to assess whether plasma concentrations of resistin differed between patients with unstable and stable angina pectoris.Methods Plasma resistin levels were determined by means of enzyme-linked immunosorbent assay (ELISA) in 46 patients with unstable angina (UAP), 37 with stable angina (SAP) and 31 control subjects.Results Plasma concentrations of resistin were significantly increased in UAP group (geometric mean (interquartile range) 12.09 ng/ml (8.40, 18.08)) in comparison with SAP (9.04 ng/ml (7.09, 11.44)) and control groups (8.71 ng/ml (6.58,11.56)). No differences in resistin levels were found between patients with SAP and controls. We also found that plasma resistin positively correlated with leukocyte counts (r=0.21, P=0.027), high sensitive C-reactive protein (hs-CRP) (r=0.25,P=0.008), and endothelin-1 (r=0.21, P=0.025) after adjustment for age, sex and BMI.Conclusion Resistin may be involved in the development of CAD by influencing systemic inflammation and endothelial activation.

  1. Myocardial bridge: The cause of angina in a young man

    International Nuclear Information System (INIS)

    Myocardial bridging is basically the systolic narrowing of epicardial coronary arteries, secondary to their tunneled course in myocardium. Though it is a benign condition it can have the symptoms like acute coronary syndrome, arrhythmias and sudden cardiac death. We report a 32-year-old male, who presented with typical exertional angina, had positive exercise treadmill and thallium-201 test. Coronary angiography revealed myocardial bridge of distal left anterior descending coronary artery. He was put on β-blockers and was doing well at 8 years of follow-up

  2. Comparison of patients undergoing enhanced external counterpulsation and spinal cord stimulation for refractory angina pectoris

    DEFF Research Database (Denmark)

    Bondesson, Susanne; Pettersson, Thomas; Erdling, André;

    2008-01-01

    with refractory angina. METHODS: 153 patients with refractory angina were treated with either EECP, SCS, or were retained on their pharmacological treatment (control). Glyceryl trinitrate usage and Canadian Cardiovascular Society classification were registered at baseline, 6 and 12 months after therapy. RESULTS...

  3. One year follow-up of patients with refractory angina pectoris treated with enhanced external counterpulsation

    DEFF Research Database (Denmark)

    Pettersson, Thomas; Bondesson, Susanne; Cojocaru, Diodor; Ohlsson, Ola; Wackenfors, Angelica; Edvinsson, Lars

    2006-01-01

    the long-term outcome of EECP treatment at a Scandinavian centre, in relieving angina in patients with chronic refractory angina pectoris. METHODS: 55 patients were treated with EECP. Canadian cardiovascular society (CCS) class, antianginal medication and adverse clinical events were collected prior...

  4. Clinical course of isolated stable angina due to coronary heart disease

    NARCIS (Netherlands)

    Poole-Wilson, Philip A.; Voko, Zoltan; Kirwan, Bridget-Anne; de Brouwer, Sophie; Dunselman, Peter H. J. M.; Lubsen, Jacobus

    2007-01-01

    Aims To describe the clinical course of patients with stable angina due to coronary heart disease without a history of cardiovascular (CV) events or revascutarization (isolated angina). Methods and results Of 7665 patients in a trial comparing long-acting nifedipine with placebo, 2170 (28%) had isol

  5. A STUDY OF HIGH SENSITIVITY C-REACTIVE PROTEIN IN UNSTABLE ANGINA

    Directory of Open Access Journals (Sweden)

    Satish

    2014-11-01

    Full Text Available BACKGROUND: Unstable angina has a wide variability in its natural history, changing concepts of Pathophysiology, and newer approaches to its management strategies. So, unstable angina still has importance and prime interest in research work. Various ongoing research works has provided newer insights in pathophysiology of unstable angina syndrome and helps in recognition of clinical variability and unpredictability of it. C - reactive protein being the most sensitive acute phase reactant currently held. A recent previous study has estimated the levels and values of high-sensitivity C - reactive protein in both stable and unstable angina pectoris. Data provided by the study indicated need for further studies in this field. With all these facts, the present study is carried out to estimated Hs CRP levels as a marker of inflammation in patient of unstable angina. AIMS AND OBJECTIVES: The present study was carried out with the following Aims and Objectives. To estimate Hs-CRP levels as a marker of inflammation in patients of unstable angina. To compare Hs-CRP levels in cases of unstable angina, with Hs-CRP levels in patients of stable angina and in healthy age and sex matched controls. MATERIAL AND METHODS: This study was carried out at Basaveshwar Teaching and General Hospital, Gulbarga, MRMC Gulbarga. Approximate duration of study was 1 ½ year from June-2008 to November, 2010. OBSERVATION: Following are the conclusions drawn from the present study.

  6. Structural and Functional Coronary Artery Abnormalities in Patients With Vasospastic Angina Pectoris

    DEFF Research Database (Denmark)

    Ong, Peter; Aziz, Ahmed; Hansen, Henrik Steen;

    2015-01-01

    coherence tomography have been applied to study the coronary pathology in patients with vasospastic angina. Patients with vasospastic angina represent a heterogeneous cohort of patients with regard to the extent of concomitant coronary atherosclerosis. They share the common pathophysiological phenomenon of...

  7. The impact of guideline compliant medical therapy on clinical outcome in patients with stable angina: findings from the Euro Heart Survey of stable angina

    DEFF Research Database (Denmark)

    Daly, Caroline; Clemens, Felicity; Lopez-Sendon, Jose L.;

    2006-01-01

    interest was death or myocardial infarction (MI). The increasing intensity of guideline compliant medical therapy was quantified by means of a simple treatment score based on the use of guideline advocated therapies: antiplatelets, statins, and beta-blockers. A total of 3779 patients were included in the...... initial survey. Increasing intensity of guideline compliant therapy at initial assessment was associated with a reduction in death and MI during follow-up in patients with angina and confirmed coronary disease (HR 0.68; 95% CI 0.49-0.95 per unit increase in treatment score). All cardiovascular events were...... stable angina. Methods and results The Euro Heart Survey of Stable Angina is a multicentre prospective observational study conducted between 2002 and 2003. Patients with a clinical diagnosis of stable angina by a cardiologist were enrolled and follow-up was conducted at 1 year. The primary outcome of...

  8. Assessing Quality of Life and Medical Care in Chronic Angina: An Internet Survey

    Science.gov (United States)

    2016-01-01

    Background Angina is a clinical syndrome whose recognition relies heavily on self-report, so its identification can be challenging. Most data come from cohorts identified by physicians and nurses at the point of care; however, current widespread access to the Internet makes identification of community cohorts feasible and offers a complementary picture of angina. Objective To describe a population self-identified as experiencing chronic angina by use of an Internet survey. Methods Using email and an Internet portal, we invited individuals with a diagnosis of angina and recent symptoms to complete an Internet survey on treatment and quality of life (QOL). In total, 1147 surveys were received. The main analysis was further limited to those reporting a definite coronary heart disease (CHD) history (N=646, 56% of overall). Results Overall, about 15% reported daily angina and 40% weekly angina. Those with more frequent angina were younger, more often depressed, and reported a shorter time since diagnosis. They also had substantially worse treatment satisfaction, physical function, and overall QOL. Fewer than 40% were on ≥ 2 anti-anginals, even with daily angina. The subjects without a history of definite CHD had unexpectedly low use of antianginal and evidence-based medicines, suggesting either a lack of specificity in the use of self-reported angina to identify patients with CHD or lack of access to care. Conclusions Use of inexpensive electronic tools can identify community-based angina cohorts for clinical research. Limitation to subjects with a definite history of CHD lends diagnostic face validity to the approach; however, other symptomatic individuals are also identified. PMID:27125492

  9. A case of relapsing polychondritis mimicking Ludwig’s angina

    Directory of Open Access Journals (Sweden)

    Adnan Agha

    2009-09-01

    Full Text Available Relapsing polychondritis (RP is a severe progressive inflammatory condition involving cartilaginous structures and caused by an autoimmune process, for which there is no confirmatory serological biomarker and which still is diagnosed on a mainly clinical basis. RP has been associated with many diseases like Sweet’s syndrome, Behcet’s disease, rheumatoid arthritis, and other autoimmune disorders. We attempt to describe here a unique case of a 38-year-old female with a high-grade fever, sore throat, difficulty in swallowing, hoarseness of the voice, and found to have signs of tongue swelling and inflammation of the oral cavity that mimicked Ludwig’s angina, necessitating antibiotic use. On careful re-evaluation the patient was diagnosed to have relapsing polychondritis based on auricular and respiratory tract chondritis and response to steroids. The purpose of this report is to emphasize the fact that careful clinical assessment is needed to diagnose RP, which may be misdiagnosed as Ludwig’s angina.

  10. Angina monocitica con sovrainfezione da Prevotella denticola: caso clinico

    Directory of Open Access Journals (Sweden)

    Maria Teresa Allù

    2005-06-01

    Full Text Available Monocytic angina with superinfection of Prevotella denticola: clinical case Monocytic angina is a clinical sindrome caused by Epstein-Barr virus characterized by fever, pharyngitis, exudative tonsillitis, swollen lymphoglands, splenomegaly and hepatomegaly.The inflamed pharynx and necrotic tonsils of infectious mononucleosis are subject to bacterial superinfection initially or during the course of the illness; the reduced PO2 tension and low oxidation-reduction potential that prevail in a vascular and necrotic tissues favour the growth of anaerobes. In this article we reported the clinical case of a ten years old children, who presented fever and tonsillopharyngitis; he was treated with cefotaxime and piperacillin, he did not improve in health. He was admitted to hospital (Department of Otorhinolaryngology. The patient was treated with aminoglycoside (tobramycin, piperacillin and cortisone; the clinical situation deteriorated. Pus sample was collected from the tonsils and cultured. Isolated strain from culture anaerobic was identified biochemically (Rapid-ID32ANA.The microorganism isolated was: Prevotella denticola (oral anaerobic gram-negative rods; β-lactamase production was tested by using the chromogenic cephalosporin disk test.The susceptibility to antibiotics was performed according to NCCLS recommendations. Prevotella denticola (β-lactamase production was resistant to penicillin, cefoxitin, cefotetan, piperacillin, clindamycin and metronidazole it was susceptible to piperacillin-tazobactam, amoxicillin-clavulanate, ticarcillin-clavulanate, imipenem and chloramphenicol. Children was treated with piperacillin-tazobactam, with rapid symptomatic relief.

  11. Efficacy of a device to narrow the coronary sinus in refractory angina

    DEFF Research Database (Denmark)

    Verheye, Stefan; Jolicœur, E Marc; Behan, Miles W; Pettersson, Thomas; Sainsbury, Paul; Hill, Jonathan; Vrolix, Mathias; Agostoni, Pierfrancesco; Engstrom, Thomas; Labinaz, Marino; de Silva, Ranil; Schwartz, Marc; Meyten, Nathalie; Uren, Neal G; Doucet, Serge; Tanguay, Jean-François; Lindsay, Steven; Henry, Timothy D; White, Christopher J; Edelman, Elazer R; Banai, Shmuel

    2015-01-01

    the coronary sinus, thus redistributing blood into ischemic myocardium. METHODS: We randomly assigned 104 patients with Canadian Cardiovascular Society (CCS) class III or IV angina (on a scale from I to IV, with higher classes indicating greater limitations on physical activity owing to angina) and...... treatment group (37 of 52 patients), as compared with 42% of those in the control group (22 of 52) (P=0.003). Quality of life as assessed with the use of the Seattle Angina Questionnaire was significantly improved in the treatment group, as compared with the control group (improvement on a 100-point scale...

  12. COMPARISON BETAXOLOL AND METOPROLOL TARTRATE THERAPIES IN PATIENTS WITH ARTERIAL HYPERTENSION ASSOCIATED WITH STABLE ANGINA

    OpenAIRE

    A.A. Anderzhanova; J. V. Gavrilov; V. A. Sulimov

    2016-01-01

    Aim. To compare antihypertensive, antianginal and antiischemic efficacy of β1-selective adrenoblockers (betaxolol and metoprolol tartrate) in patients with arterial hypertension (HT) of 1-2 degree associated with stable angina class II.Material and methods. 100 patients (aged 23-66 y.o.) with HT associated with stable angina or without angina were involved in the study. Patients were randomized into 2 groups (G1 and G2). G1 patients were treated with betaxolol, and G2 patients – with metoprol...

  13. An Unusual Case of Suspected Microvascular Angina in a Newborn

    Directory of Open Access Journals (Sweden)

    Stefania Cataldo

    2012-01-01

    Full Text Available Myocardial ischemia in pediatric population is uncommon and usually due to congenital heart disease or extracardiac conditions leading to poor coronary perfusion. A 6-day-old newborn presented with respiratory distress and signs of heart failure. ECG, echocardiography, and laboratory results were consistent with myocardial ischemia. Coronary angiography was performed to exclude anomalous origin of coronary arteries, showing normal coronary artery origin and course. Thrombophilia and extra-cardiac causes were ruled out. Clinical conditions improved with mechanical ventilation and diuretics, enzyme levels lowered, repolarisation and systolic function abnormalities regressed, but ischemic electrocardiographic and echocardiographic signs still presented during intense crying. Becaues of suspicion of microvascular angina, therapy with ASA and beta-blocker was started. At 5 month followup, the baby was in good clinical condition and no more episodes were recorded. We believe it is an interesting case, as no similar cases have been recorded till now.

  14. Invaliderende angina pectoris behandlet med elektrisk rygmarvsstimulation (ERS)

    DEFF Research Database (Denmark)

    Andersen, C; Clemensen, S E; Henneberg, S W;

    1992-01-01

    Thirty patients who had severe incapacitating angina pectoris which had not reacted to the conventional therapeutic measures and which required massive daily opioid consumption were treated with electrical spinal cord stimulation (SCS) by means of a completely implantable stimulation system. The...... therapeutic effect was good in 87% of the patients who experienced considerably reduced frequency of attacks and markedly reduced opioid consumption (p less than 0.00005). Nine of the patients could reduce opioid consumption and 14 out of 27 could cease their otherwise daily opioid consumption. In four...... patients, the therapeutic effect was unsatisfactory. In the first 22 patients in whom a unipolar electrode was introduced, displacement of the electrode and subsequent reoperation was a frequent problem. This problem disappeared after change to multipolar electrodes as slight changes in placing of the...

  15. Predicting prognosis in stable angina - results from the Euro heart survey of stable angina: prospective observational study

    DEFF Research Database (Denmark)

    Daly, Caroline A.; De Stavola, Bianca; Sendon, Jose L. Lopez;

    2006-01-01

    -European survey in 156 outpatient cardiology clinics. Participants 3031 patients were included on the basis of a new clinical diagnosis by a cardiologist of stable angina with follow-up at one year. Main outcome measure Death or non-fatal myocardial infarction. Results The rate of death and non-fatal myocardial...... infarction in the first year was 2.3 per 100 patient years; the rate was 3.9 per 100 patient years in the subgroup (n = 994) with angiographic confirmation of coronary disease. The clinical and investigative factors most predictive of adverse outcome were comorbidity, diabetes, shorter duration of symptoms......, increasing severity of symptoms, abnormal ventricular function, resting electrocardiogaphic changes, or not having any stress test done. Results of non-invasive stress tests did not significantly predict outcome in the population who had tests done. A score was constructed using the parameters predictive of...

  16. Evaluating Symptoms to Improve Quality of Life in Patients with Chronic Stable Angina

    Directory of Open Access Journals (Sweden)

    Jeffrey W. Young

    2013-01-01

    Full Text Available Chronic stable angina (CSA is a significant problem in the United States that can negatively impact patient quality of life (QoL. An accurate assessment of the severity of a patient’s angina, the impact on their functional status, and their risk of cardiovascular complications is key to successful treatment of CSA. Active communication between the patient and their healthcare provider is necessary to ensure that patients receive optimal therapy. Healthcare providers should be aware of atypical symptoms of CSA in their patients, as patients may continue to suffer from angina despite the availability of multiple therapies. Patient questionnaires and symptom checklists can help patients communicate proactively with their healthcare providers. This paper discusses the prevalence of CSA, its impact on QoL, and the tools that healthcare providers can use to assess the severity of their patients’ angina and the impact on QoL.

  17. Treatment of refractory chest angina with spinal electrical stimulator: literature review

    International Nuclear Information System (INIS)

    There is a group of patients with chronic refractory chest angina, who are not ideal candidates for surgical or percutaneous revascularization and who although having a good medical handling continues to experience severe episodes of angina. The spinal electrical stimulator is a neuromodulators used as an alternative to treat these patients. The objective is to realize a review of scientific literature regarding the spinal electric stimulation in the treatment of chest angina, its mechanism of action, benefits and its cost effectiveness. Materials and methods: using the Cochrane methodology, a search of articles published from January 1980 to January 2007 in Medline using the terms spinal cord stimulation, was realized. The papers considered most pertinent were selected. Conclusions: the anti-ischemic effect of the electrical spinal stimulator reduces the episodes of chest angina, improves the quality of life and the tolerance to exercise, diminishes the hospital stay and delays the appearance of ischemic signs

  18. Gender differences in the management and clinical outcome of stable angina

    DEFF Research Database (Denmark)

    Daly, Caroline; Clemens, Felicity; Sendon, Jose L. Lopez;

    2006-01-01

    , 1.13 to 3.85), even after multivariable adjustment for age, abnormal ventricular function, severity of coronary disease, and diabetes. Conclusions- Significant gender bias has been identified in the use of investigations and evidence-based medical therapy in stable angina. Women were also less......Background- We sought to examine the impact of gender on the investigation and subsequent management of stable angina and to assess gender differences in clinical outcome at 1 year. Methods and Results- The Euro Heart Survey of Stable Angina enrolled patients with a clinical diagnosis of stable...... likely to be revascularized. The observed bias is of particular concern in light of the adverse prognosis observed among women with stable angina and confirmed coronary disease....

  19. Respiratory compromise: a rare complication of transcutaneous electrical nerve stimulation for angina pectoris.

    OpenAIRE

    Mann, C. J.

    1996-01-01

    Electrical stimulation of any muscle group may produce tetany. If the intercostal muscles are involved this may lead to respiratory embarrasment. A case is presented in which transcutaneous electrical nerve stimulation (TENS) treatment for angina pectoris resulted in respiratory arrest.

  20. Angina and exertional myocardial ischemia in diabetic and nondiabetic patients: assessment by exercise thallium scintigraphy

    International Nuclear Information System (INIS)

    Patients with diabetes mellitus and coronary artery disease are thought to have painless myocardial ischemia more often than patients without diabetes. We studied 50 consecutive patients with diabetes and 50 consecutive patients without diabetes, all with ischemia, on exercise thallium scintigraphy to show the reliability of angina as a marker for exertional ischemia. The two groups had similar clinical characteristics, treadmill test results, and extent of infarction and ischemia, but only 7 patients with diabetes compared with 17 patients without diabetes had angina during exertional ischemia. In diabetic patients the extent of retinopathy, nephropathy, or peripheral neuropathy was similar in patients with and without angina. Angina is an unreliable index of myocardial ischemia in diabetic patients with coronary artery disease. Given the increased cardiac morbidity and mortality in such patients, periodic objective assessments of the extent of ischemia are warranted

  1. Five year prognosis in patients with angina identified in primary care: incident cohort study

    OpenAIRE

    Buckley, B. S.; Simpson, C.R.; McLernon, D.J.; Murphy, A W; Hannaford, P.C.

    2009-01-01

    OBJECTIVE: To ascertain the risk of acute myocardial infarction, invasive cardiac procedures, and mortality among patients with newly diagnosed angina over five years. DESIGN: Incident cohort study of patients with primary care data linked to secondary care and mortality data. SETTING: 40 primary care practices in Scotland. PARTICIPANTS: 1785 patients with a diagnosis of angina as their first manifestation of ischaemic heart disease, 1 January 1998 to 31 December 2001. MAIN OUTCOME MEASURES: ...

  2. Dental Calculus Links Statistically to Angina Pectoris: 26-Year Observational Study.

    Directory of Open Access Journals (Sweden)

    Birgitta Söder

    Full Text Available Dental infections, such as periodontitis, associate with atherosclerosis and its complications. We studied a cohort followed-up since 1985 for incidence of angina pectoris with the hypothesis that calculus accumulation, proxy for poor oral hygiene, links to this symptom.In our Swedish prospective cohort study of 1676 randomly selected subjects followed-up for 26 years. In 1985 all subjects underwent clinical oral examination and answered a questionnaire assessing background variables such as socio-economic status and pack-years of smoking. By using data from the Center of Epidemiology, Swedish National Board of Health and Welfare, Sweden we analyzed the association of oral health parameters with the prevalence of in-hospital verified angina pectoris classified according to the WHO International Classification of Diseases, using descriptive statistics and logistic regression analysis.Of the 1676 subjects, 51 (28 women/23 men had been diagnosed with angina pectoris at a mean age of 59.8 ± 2.9 years. No difference was observed in age and gender between patients with angina pectoris and subjects without. Neither was there any difference in education level and smoking habits (in pack years, Gingival index and Plaque index between the groups. Angina pectoris patients had significantly more often their first maxillary molar tooth extracted (d. 16 than the other subjects (p = 0.02. Patients also showed significantly higher dental calculus index values than the subjects without angina pectoris (p = 0.01. Multiple regression analysis showed odds ratio 2.21 (95% confidence interval 1.17-4.17 in the association between high calculus index and angina pectoris (p = 0.015.Our study hypothesis was confirmed by showing for the first time that high dental calculus score indeed associated with the incidence of angina pectoris in this cohort study.

  3. Neurostimulation as an adjuvant therapy for patients with intractable angina pectoris.

    OpenAIRE

    Jongste, Michel Johannes Leendert de

    2009-01-01

    In spite of tremendous improvement in treatment of patients with angina pectoris due to significant coronary artery disease, there remains a group of patients who cannot adequately be treated. These patients are considered as having ‘intractale angina’. Patients, suffering from intractable ischemic disease have never been defined as a separate group and no data are available regarding their morbidity and mortality. Furthermore, since their angina was 'intractable’, no therapy was offered to i...

  4. Nicorandil in patients with acute coronary syndrome and stable angina undergoing Percutaneous Coronary Intervention: literature review

    OpenAIRE

    Neda Partovi; Homa Falsoleiman

    2014-01-01

    Percutaneous coronary intervention is an option for the treatment of coronary artery disease such as acute coronary syndrome and stable angina.Acute coronary syndrome has two groups including acute myocardial infarction and unstable angina.Periprocedural myocardial infarction is a frequent and prognostically important complication of percutaneous coronary intervention and can be easily monitored by measuring myocardial enzymes. Coronary microvascular dysfunction in patients undergoing primary...

  5. Prognostic value of early post-infarction angina in elderly patients

    OpenAIRE

    Erceg Predrag; Davidović Mladen; Vasiljević Zorana; Mitrović Predrag M.; Vukčević Vladan D.; Milošević Dragoslav P.; Stević Radmila; Rajić Miodrag

    2005-01-01

    Although numerous studies have shown that early post-infarction angina was a predictor of poor prognosis in patients with acute myocardial infarction, not a single study has considered this issue in the elderly. The goal of this study, based on a five-year follow-up of elderly patients with acute myocardial infarction, was to determine whether early post-infarction angina in the elderly had any influence on mortality and the incidence of additional coronary events. The study population consis...

  6. Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion

    OpenAIRE

    Sun, Zhen; Shen, Ying; Lu, Lin; Zhang, Rui-yan; Pu, Li-jin; Zhang, Qi; Yang, Zheng-kun; Hu, Jian; Chen, Qiu-jing; Shen, Wei-Feng

    2013-01-01

    Objective: Coronary collateral circulation is an alternative source of blood supply to myocardium in the presence of advanced coronary artery disease. We sought to determine which clinical and angiographic variables are associated with collateral development in patients with stable angina and chronic total coronary occlusion. Methods: Demographic variables, biochemical measurements, and angiographic findings were collected from 478 patients with stable angina and chronic total coronary occlus...

  7. Ventetid og omkostninger ved diagnostik og behandling af stabil angina pectoris

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Sanchez, Ricardo

    Introduction: The objective of this pilot study was to examine possible consequences of a logistically non-optimal regimen, for the diagnosis and treatment of stable angina pectoris, on waiting time and costs to inform whether a larger study is warranted. Material and methods: Retrospective cohor...... stable angina pectoris, which ceteris paribus would be associated with cost savings in the health care sector. However, these potentials should be examined in a larger- scale study....

  8. Dental Calculus Links Statistically to Angina Pectoris: 26-Year Observational Study

    Science.gov (United States)

    2016-01-01

    Objectives Dental infections, such as periodontitis, associate with atherosclerosis and its complications. We studied a cohort followed-up since 1985 for incidence of angina pectoris with the hypothesis that calculus accumulation, proxy for poor oral hygiene, links to this symptom. Methods In our Swedish prospective cohort study of 1676 randomly selected subjects followed-up for 26 years. In 1985 all subjects underwent clinical oral examination and answered a questionnaire assessing background variables such as socio-economic status and pack-years of smoking. By using data from the Center of Epidemiology, Swedish National Board of Health and Welfare, Sweden we analyzed the association of oral health parameters with the prevalence of in-hospital verified angina pectoris classified according to the WHO International Classification of Diseases, using descriptive statistics and logistic regression analysis. Results Of the 1676 subjects, 51 (28 women/23 men) had been diagnosed with angina pectoris at a mean age of 59.8 ± 2.9 years. No difference was observed in age and gender between patients with angina pectoris and subjects without. Neither was there any difference in education level and smoking habits (in pack years), Gingival index and Plaque index between the groups. Angina pectoris patients had significantly more often their first maxillary molar tooth extracted (d. 16) than the other subjects (p = 0.02). Patients also showed significantly higher dental calculus index values than the subjects without angina pectoris (p = 0.01). Multiple regression analysis showed odds ratio 2.21 (95% confidence interval 1.17–4.17) in the association between high calculus index and angina pectoris (p = 0.015). Conclusion Our study hypothesis was confirmed by showing for the first time that high dental calculus score indeed associated with the incidence of angina pectoris in this cohort study. PMID:27336307

  9. Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris

    OpenAIRE

    Mohammed Aldakkak; Stowe, David F; Camara, Amadou K.S.

    2013-01-01

    Coronary heart disease is a global malady and it is the leading cause of death in the United States. Chronic stable angina is the most common manifestation of coronary heart disease and it results from the imbalance between myocardial oxygen supply and demand due to reduction in coronary blood flow. Therefore, in addition to lifestyle changes, commonly used pharmaceutical treatments for angina (nitrates, β-blockers, Ca2+ channel blockers) are aimed at increasing blood flow or decreasing O2 de...

  10. Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization

    Directory of Open Access Journals (Sweden)

    Richard Kones

    2010-08-01

    Full Text Available Richard KonesThe Cardiometabolic Research Institute, Houston, Texas, USAAbstract: The objectives in treating angina are relief of pain and prevention of disease ­progression through risk reduction. Mechanisms, indications, clinical forms, doses, and side effects of the traditional antianginal agents – nitrates, ß-blockers, and calcium channel ­blockers – are reviewed. A number of patients have contraindications or remain unrelieved from anginal discomfort with these drugs. Among newer alternatives, ranolazine, recently approved in the United States, indirectly prevents the intracellular calcium overload involved in cardiac ischemia and is a welcome addition to available treatments. None, however, are disease-modifying agents. Two options for refractory angina, enhanced external counterpulsation and spinal cord stimulation (SCS, are presented in detail. They are both well-studied and are effective means of treating at least some patients with this perplexing form of angina. Traditional modifiable risk factors for coronary artery disease (CAD – smoking, hypertension, dyslipidemia, ­diabetes, and obesity – account for most of the population-attributable risk. Individual therapy of high-risk patients differs from population-wide efforts to prevent risk factors from appearing or reducing their severity, in order to lower the national burden of disease. Current American College of Cardiology/American Heart Association guidelines to lower risk in patients with chronic angina are reviewed. The Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE trial showed that in patients with stable angina, optimal medical therapy alone and percutaneous coronary intervention (PCI with medical therapy were equal in preventing myocardial infarction and death. The integration of COURAGE results into current practice is discussed. For patients who are unstable, with very high risk, with left main coronary artery lesions, in

  11. Evaluation of coronary microvascular function in patients with vasospastic angina

    Directory of Open Access Journals (Sweden)

    Ken Ishibashi

    2013-01-01

    Full Text Available AIM: To investigate endothelium-dependent and -independent coronary microvascular functions in patients with vasospastic angina (VSA. METHODS: Thirty-six patients with VSA (30 men and 6 women; mean age, 58 years were enrolled in this study. VSA was defined as ≥ 90% narrowing of the epicardial coronary arteries on angiography performed during a spasm provocation test, presence of chest pain, and/or ST-segment deviation on an electrocardiogram (ECG. Patients (n = 36 with negative spasm provocation test results and those matched for age and sex were enrolled as a control group (nonVSA group. Low-dose acetylcholine (ACh; 3 μg/min was infused into the left coronary ostium for 2 min during the spasm provocation test. Following the spasm provocation test, nitroglycerin (0.2 mg was administered intracoronally. Coronary blood flow (was calculated from quantitative angiography and Doppler flow velocity measurements, and the coronary flow reserve was calculated as the ratio of coronary flow velocity after injection of adenosine triphosphate (20 μg to the baseline value. Changes in the coronary artery diameter in response to ACh and nitroglycerin infusion were expressed as percentage changes from baseline measurements. RESULTS: Body mass index was significantly lower in the VSA group than in the nonVSA group. The frequency of conventional coronary risk factors and the rate of statin use were similar between the 2 groups. The left ventricular ejection fraction as evaluated by echocardiography was similar between the 2 groups. The duration of angina was 9 ± 2 mo. The results of blood chemistry analysis were similar between the 2 groups. Low-dose ACh did not cause coronary spasms. The change in coronary artery diameter in response to ACh was lower in the VSA group (-1.4% ± 9.3% than in the nonVSA group (3.1% ± 6.5%, P < 0.05, whereas nitroglycerin-induced coronary artery dilatation and coronary blood flow increase in response to ACh or coronary flow

  12. Importance of thrombosis and thrombolysis in silent ischaemia: comparison of patients with acute myocardial infarction and unstable angina.

    OpenAIRE

    Gurfinkel, E.; Altman, R.; Scazziota, A.; Rouvier, J.; Mautner, B

    1994-01-01

    OBJECTIVE--To investigate whether plaque rupture and thrombosis have a role in silent ischaemia as well as in unstable angina. DESIGN--Prospective analysis of the results of haemostatic diagnostic tests at the moment of developing silent ischaemia at rest. SETTING--Coronary care unit. PATIENTS--22 patients with acute myocardial infarction, 12 patients with symptomatic angina (unstable angina), and 10 normal volunteers (control group). INTERVENTIONS--Continuous cardiac monitoring detected 15 a...

  13. Actitudes hacia la ciencia en primaria y secundaria.

    OpenAIRE

    Pérez Manzano, Antonio

    2013-01-01

    Se ha tratado de explorar qué actitudes tienen los niños y adolescentes respecto a la ciencia y la tecnología. El tamaño muestral ha sido de 6.827 cuestionarios, de los que 3.895 (57.1%) correspondieron a Educación Primaria y 2.932 (42.9%) a Educación Secundaria Obligatoria, representando una fracción de muestreo del 1.5 por mil. La información recogida nos ha permitido analizar las diferencias en cuanto a género, tipo de centro educativo (público o privado), nivel (Primaria vs Secundar...

  14. Effect of anxiety and depression on endothelial function and inflammation degree of coronary heart disease patients with angina pectoris

    Institute of Scientific and Technical Information of China (English)

    Lin Ni; Xiang-Yang Xia; Ka Han; Yong-Xin Wu

    2016-01-01

    Objective:To study the effect of anxiety and depression on endothelial function and inflammation degree of coronary heart disease patients with angina pectoris.Methods: 80 cases of patients diagnosed with angina pectoris of coronary heart disease in our hospital from May 2012 to August 2014 were enrolled for study; anxiety and depression were judged by anxiety subscale (HADS-a) and depression subscale (HADS-d). Endothelial progenitor cell and endothelial microparticle contents in peripheral blood as well as serum ET-1, CGRP, IL-6, IL-6R, IL-18, ADAMTS-1 and NO contents were detected.Results:EPC, NO and CGRP contents of angina pectoris patients with anxiety were lower than those of angina pectoris patients without anxiety, and EMP, ET-1, IL-6, IL-6R, IL-18 and ADAMTS-1 contents were higher than those of angina pectoris patients without anxiety; EPC, NO and CGRP contents of angina pectoris patients with depression were lower than those of angina pectoris patients without depression, and EMP, ET-1, IL-6, IL-6R, IL-18 and ADAMTS-1 contents were higher than those of angina pectoris patients without depression.Conclusions:Angina pectoris of coronary heart disease patients complicated with anxiety and depression have endothelial dysfunction and inflammatory reaction activation; endothelial dysfunction and inflammatory reaction activation are possible pathways that anxiety and depression cause the progression of coronary heart disease.

  15. Atención Primaria de Salud

    Directory of Open Access Journals (Sweden)

    Manuel Bauzá Díaz

    2014-08-01

    Full Text Available Los procesos asistenciales, docentes e investigativos son funciones esenciales de la salud pública; que adquieren su mayor impacto ambiental, social y económico cuando los procesos administrativos tienen orientación científica. Cada una de estas funciones se caracteriza por su alta complejidad, variada composición, el alcance de una dimensión social, elevada dinámica de realización y atributos propios. El efecto de esos procesos depende, esencialmente, de su capacidad para integrarse en un sistema armónico y coherente que requiere de la participación multidisciplinaria del sector salud, la intersectorial social y la participación comunitaria. De lo planteado anteriormente se puede deducir que el estudio, análisis, diseño y ejecución de estos procesos requieren un enfoque en sistema, así como un pensamiento científico (clínico y epidemiológico. Desde la Medicina General Integral (MGI se trabaja sobre acciones de intervención, orientadas a la promoción, la prevención, el diagnóstico, el tratamiento y la rehabilitación; con acciones dirigidas al individuo, la familia, los grupos y/o colectivos, la comunidad y el medio ambiente, como acciones para la mejor solución de los problemas de salud. La MGI es una disciplina sistémica, pues justamente descansa en entender los fenómenos del proceso salud-enfermedad en su integridad, en su diversidad, con particularidades y dinámicas desde el individuo y hasta la comunidad. Como sistema, contiene numerosas singularidades, pero, en conjunto con otros sectores sociales y económicos, participa activamente en pro de la salud de la población. Los decisores en salud deben considerar esta unidad integral y metodológica, lo que se traduce a la utilización del enfoque clínico y epidemiológico. La formación amplia de profesionales desde la Atención Primaria de Salud (APS implica la alineación de médicos plenamente identificados con estas funciones y capaces de contribuir

  16. Critical evaluation of ivabradine for the management of chronic stable angina

    Directory of Open Access Journals (Sweden)

    Khan W

    2011-09-01

    Full Text Available Waqas Khan, Jeffrey S BorerDivision of Cardiovascular Medicine and the Department of Medicine, State University of New York Downstate Medical Center and College of Medicine, Brooklyn and New York, NY, USAAbstract: Angina pectoris is the most common symptom of coronary artery disease (CAD. Angina results from an imbalance between myocardial oxygen supply and demand. Heart rate (HR reduction can beneficially alter both elements of this imbalance by increasing diastolic filling time and reducing myocardial oxygen demand. Therefore, HR reduction is an accepted approach to angina prevention. ß-blockers, calcium-channel blockers, and long-acting nitrates are currently the cornerstones in prevention and management of stable angina. However, use of these treatments may be limited by adverse effects or development of tolerance. Thus, additional approaches to angina prevention may be useful for many patients with CAD. The discovery of the f-channel and the resulting current, If, that modulates the rate of spontaneous diastolic depolarization of sinoatrial nodal (SAN myocytes led to the study of these channels as targets for lowering HR. This resulted in the development of a novel agent, ivabradine, a selective and specific If inhibitor. Ivabradine slows the slope of diastolic depolarization of the action potential in the SAN cells, decreasing HR at rest and during exercise, but has no other cardiovascular effects. In different subpopulations with chronic stable angina, ivabradine markedly improves exercise capacity and significantly decreases the number of ambient angina attacks. In a post-hoc analysis of the BEAUTIFUL trial (morBidity-mortality EvAlUaTion of the If inhibitor ivabradine in patients with coronary disease and left-ventricULar dysfunction, ivabradine also reduced mortality, myocardial infarctions, and heart failure hospitalizations among patients with angina. To date, the drug has been well tolerated; transient visual disturbances and

  17. The efficacy of trimetazidine on stable angina pectoris: a meta-analysis of randomized clinical trials.

    Science.gov (United States)

    Peng, Song; Zhao, Min; Wan, Jing; Fang, Qi; Fang, Dong; Li, Kaiyong

    2014-12-20

    This meta-analysis aimed to evaluate the efficacy of trimetazidine in combination with other anti-anginal drugs versus other anti-anginal drugs in the treatment of stable angina pectoris (SAP). Randomized controlled trials (RCTs) published in English and Chinese were retrieved from computerized databases: Embase, PubMed, and CNKI. Primary outcomes consist of clinical parameters (numbers of weekly angina attacks and nitroglycerin use) and ergometric parameters (time to 1mm ST-segment depression, and total work (in Mets) and exercise duration (in seconds) at peak exercise) in stable angina pectoris treated by trimetazidine or not. The quality of studies was evaluated using Jadad score. Data analysis of 13 studies was performed using Stata 12.0 software. Results showed that treatment of trimetazidine and other anti-anginal drugs was associated with a smaller weekly mean number of angina attacks (WMD=-0.95, 95%CI: -1.30 to -0.61, Z=5.39, Ptrimetazidine in the treatment of stable angina pectoris, in comparison with conventional antianginal agents, regardless of treatment duration. PMID:25466565

  18. Relationship between the serologic status of helicobacter pylori with the presence of unstable angina

    International Nuclear Information System (INIS)

    To determine whether unstable angina is co-related to seropositivity to chronic Helicobacter pylori (HP) infection. It is a case control, descriptive study conducted at CCU in Razi Hospital in Ahwaz a city southwest Iran, from 2004 to 2005. We measured serum HP- lgG levels of participants in CCU in a hospital. Blood samples were drawn during study period from 96 patients (mean age 56 years) with Unstable Angina (UA) according to American Heart Association criteria and from 96 participants free of cardiovascular disease (mean age 58 years) and stored at 20 degree C. Serology results were studied in relation to UA. Using chi squared test, odds ratios (OR) and 95% confidence intervals (CI) were calculated, adjusting for age, gender, and established risk factors. Seventy nine (82.3%) of patients with unstable angina and 55(61.1%) in the control group presented a positive anti HP-lgG. Odds ratio was 3 with 95% CI: 1.9 to 4.3. There was significant relation between HP-lgG positivity and unstable angina (P0.05). Our study revealed relationship between seropositivity of HP-lgG and unstable angina. (author)

  19. A new scoring system to stratify risk in unstable angina

    Directory of Open Access Journals (Sweden)

    Salzberg Simón

    2003-08-01

    Full Text Available Abstract Background We performed this study to develop a new scoring system to stratify different levels of risk in patients admitted to hospital with a diagnosis of unstable angina (UA, which is a complex syndrome that encompasses different outcomes. Many prognostic variables have been described but few efforts have been made to group them in order to enhance their individual predictive power. Methods In a first phase, 473 patients were prospectively analyzed to determine which factors were significantly associated with the in-hospital occurrence of refractory ischemia, acute myocardial infarction (AMI or death. A risk score ranging from 0 to 10 points was developed using a multivariate analysis. In a second phase, such score was validated in a new sample of 242 patients and it was finally applied to the entire population (n = 715. Results ST-segment deviation on the electrocardiogram, age ≥ 70 years, previous bypass surgery and troponin T ≥ 0.1 ng/mL were found as independent prognostic variables. A clear distinction was shown among categories of low, intermediate and high risk, defined according to the risk score. The incidence of the triple end-point was 6 %, 19.2 % and 44.7 % respectively, and the figures for AMI or death were 2 %, 11.4 % and 27.6 % respectively (p Conclusions This new scoring system is simple and easy to achieve. It allows a very good stratification of risk in patients having a clinical diagnosis of UA. They may be divided in three categories, which could be of help in the decision-making process.

  20. Presentación “Atención primaria y Universidad”.

    OpenAIRE

    Ortega-Marlasca, Manuel-María; Ruiz Cabrera, Diana

    2015-01-01

    Primera edición creada por la Srta. Diana Ruiz Cabrera como representante de Medicina de Atención Primaria del Consejo Estatal de Estudiantes de Medicina y ampliada por el Dr. Manuel Mª Ortega Marlasca como Vocal de Atención Primaria del Excmo. Colegio Oficial de Médicos de Cádiz.

  1. The initial management of stable angina in Europe, from the Euro Heart Survey: a description of pharmacological management and revascularization strategies initiated within the first month of presentation to a cardiologist in the Euro Heart Survey of Stable Angina.

    NARCIS (Netherlands)

    Daly, C.A.; Clemens, F.; Lopez-Sendon, J.; Tavazzi, L.; Boersma, E.; Danchin, N.; Delahaye, F.; Gitt, A.; Julian, D.; Mulcahy, D.; Ruzyllo, W.; Thygesen, K.; Verheugt, F.W.A.; Fox, K.M.

    2005-01-01

    AIMS: In order to assess adherence to guidelines and international variability in management, the Euro Heart Survey of Newly Presenting Angina prospectively studied medical therapy, percutaneous coronary intervention (PCI), and surgery in patients with new-onset stable angina in Europe. METHODS AND

  2. Effects on blood pressure in patients with refractory angina pectoris after enhanced external counterpulsation

    DEFF Research Database (Denmark)

    Bondesson, Susanne; Pettersson, Thomas; Ohlsson, Børje Ola Mattias;

    2010-01-01

    OBJECTIVE: Enhanced external counterpulsation (EECP) is a non-invasive technique that has been shown to reduce the frequency and severity of angina pectoris. Little is known how EECP affects the blood pressure. METHODS: 153 patients with refractory angina were treated with either EECP or retained...... on their pharmacological treatment (reference group). Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP) and heart rate were measured pre- and post-treatment and at 12 months follow-up. RESULTS: EECP treatment altered the blood pressure in patients with...... refractory angina pectoris. A decrease in the blood pressure was more common in the EECP group compared with the reference group. In the reference group, an increase in the blood pressure was more common. A correlation between a decrease in blood pressure after EECP treatment and a higher baseline MAP, SBP...

  3. Las organizaciones primarias y las empresas. Primera sección/ Las organizaciones primarias y las empresas. Segunda sección. [Reseña

    OpenAIRE

    Moros, E. (Enrique)

    2008-01-01

    Reseñas de L. POLO, Las organizaciones primarias y las empresas. Primera sección. Cuadernos empresa y humanismo, n° 99, Instituto Empresa y Humanismo, Pamplona 2007, 114 pp., 16,5 X 24, ISSN 978-1139-8698.—, Las organizaciones primarias y las empresas. Segunda sección. Cuadernos empresa y humanismo, n° 100, Instituto Empresa y Humanismo, Pamplona 2007, 148 pp., 16,5 x 24, ISSN 1139-8698.

  4. Die Bedeutung der Kaliumkanalöffner für die Therapie der Angina pectoris

    Directory of Open Access Journals (Sweden)

    Auer J

    2003-01-01

    Full Text Available In der Behandlung der koronaren Herzkrankheit ist primär die Senkung der Ereignisrate (Mortalität, Koronarletalität, Myokardinfarkt, rezidivierende Angina, Insult, Herzinsuffizienz, Revaskularisationen anzustreben. Zusätzlich ist die Zielsetzung der antianginösen Therapie vor allem die Verbesserung der Belastungstoleranz sowie die Reduktion von ischämiebedingten Folgeerscheinungen. Für die antianginöse Therapie stehen vier Wirkstoffklassen zur Verfügung, die ein differenziertes Vorgehen erlauben und die wahlweise als Monotherapien oder in Kombination in der Therapie der stabilen Angina pectoris zur Anwendung kommen können: Betablocker, Nitrate, Kalziumantagonisten und Kaliumkanalöffner. Im Rahmen der IONA-Studie (Impact Of Nicorandil in Angina wurde rezent überprüft, ob unter einer Therapie mit Nicorandil bei Patienten mit chronisch stabiler Angina pectoris die Häufigkeit schwerwiegender koronarer Ereignisse verringert werden könnte. Mit dieser Studie konnte nun ein eindeutiger Hinweis für eine Reduktion ischämiebezogener klinischer Ereignisse unter Nicorandil bei Patienten mit Angina pectoris nachgewiesen werden. Während für die antianginöse Therapie bisher lediglich eine symptomlindernde Wirkung zweifelsfrei dokumentiert ist, verbessern Maßnahmen zur Verhinderung von Thrombose- und Atheromentwicklung die Prognose (Aspirin, Cumarine, ACE-Hemmer und Lipidsenker [Statine] sowie Lebensstilmodifikation einschließlich Nikotinkarenz. Grundsätzlich sollte darüber hinaus bei Patienten mit Angina-pectoris-Beschwerden immer die Option einer Koronarangiographie und Koronarintervention (PTCA, Stent, Bypass überlegt werden.

  5. [Thiotriazoline in the Treatment of Stable Angina Pectoris of II-III Functional Class].

    Science.gov (United States)

    Kadin, D V; Chumak, B A; Filippov, A E; Shustov, S B

    2015-01-01

    Trimetazidine is a metabolic agent of proven efficacy in improving myocardial ischemia and angina. A comparative international multicenter randomized trial, assessed anti-anginal anti ischemic efficacy and safety of Trimetazidine (60 mg/d) and Thiotriazoline (600 mg/d) in symptomatic patients with chronic ischemic heart disease receiving the first line therapy. The study assessed the efficacy of the two drugs on total exercise duration, time to 1-mm ST segment depression, the number of angina attacks and nitroglycerin tablets consumed amount. Both drugs have demonstrated clinical efficacy equal for all primary and secondary endpoints. PMID:26761968

  6. Mejorando el aprendizaje lector en los alumnos de Primaria

    OpenAIRE

    Zubiauz de Pedro, Begoña; Mayor Cinca, María Ángeles

    2008-01-01

    El objetivo del estudio que se describe es demostrar la eficacia de un programa de enriquecimiento de la conciencia fonémica, desarrollado dentro del aula, y su efecto sobre las habilidades de lectura y escritura, en alumnos de 2º de Primaria. La comparación pre-post entrenamiento, entre los grupos experimental y control, mostró una mejora significativa, tanto en conciencia fonémica como en la lectura de palabras. Se concluye la necesidad de mantener una instrucción adaptada para aquellos alu...

  7. La lectoescritura en Educación Primaria

    OpenAIRE

    Lucas Griñán, Vanessa

    2014-01-01

    La lectura y la escritura no sólo podemos definirlas como meras herramientas académicas, si no como unos instrumentos fundamentales para el crecimiento personal y social de los individuos. En el presente trabajo realizaremos un análisis de la lectura y la escritura en la etapa de Educación Primaria, los diferentes métodos para trabajarlas, dentro y fuera de la escuela, además de las diferentes actividades a desarrollar para alcanzar los objetivos propuestos y la consecución de ...

  8. Conductas violentas en la etapa de educaci??n primaria

    OpenAIRE

    Carrillo Esteban, B??rbara

    2014-01-01

    La agresividad suscita un gran inter??s y preocupaci??n entre la poblaci??n ya que tiene graves consecuencias en el ??mbito familiar y escolar, de ah?? la importancia de conocer y comprender su naturaleza. Por ello en esta investigaci??n se pretende determinar el nivel de conductas violentas, lugar de residencia, rendimiento acad??mico, y actividad f??sica en los ni??os y ni??as de la etapa de Educaci??n Primaria de la provincia de Granada as?? como identificar si existen relaciones de los co...

  9. La educación vial en Primaria

    OpenAIRE

    Concejo Vera, Pedro José

    2015-01-01

    Con este Trabajo de Fin de Grado de Maestro en Educación Primaria pretendo hacer una propuesta de intervención basada en la educación vial, así mismo este proyecto busca lograr la formación integral de los alumnos en el ámbito de la educación vial y con ello lograr que los alumnos sean capaces de desenvolverse con seguridad dentro de su ciudad, por ello se realizarán experiencias próximas ligadas al contexto en el que viven para lograr que adquieran hábitos seguros y de prevenc...

  10. Chronic stable angina is associated with lower health-related quality of life: evidence from Chinese patients.

    Directory of Open Access Journals (Sweden)

    Jing Wu

    Full Text Available OBJECTIVES: To compare health-related quality of life (HRQoL between patients with stable angina and the general population in China and to examine factors associated with HRQoL among patients with stable angina. METHODS: A cross-sectional HRQoL survey of stable angina patients recruited from 4 hospitals (n = 411 and the general population recruited from 3 Physical Examination Centers (n = 549 was conducted from July to December, 2011 in two large cities, Tianjin and Chengdu. HRQoL was assessed using the EQ-5D, EQ-VAS, and SF-6D instruments. The health status specific to patients with stable angina was assessed using the Seattle Angina Questionnaire (SAQ. Information on socio-demographic, clinical, and lifestyle factors were also collected. Nested regressions were performed to explore how these factors were associated with HRQoL in patients with stable angina. RESULTS: Compared with the general population (44.2 ± 10 years, 49.9% females, stable angina patients (68.1 ± 12 years, 50.4% females had significantly lower HRQoL scores in EQ-5D utility index (0.75 ± 0.19 vs. 0.90 ± 0.20, p<0.05, SF-6D utility index (0.68 ± 0.12 vs. 0.85 ± 0.11, p<0.05, and EQ-VAS (71.2 ± 12.3 vs. 83.9 ± 10.9, p<0.05. The differences remained (-0.05 for EQ-5D, -9.27 for EQ-VAS and -0.13 for SF-6D after controlling for socio-economic characteristics. SAQ scores showed that stable angina patients experienced impaired disease-specific health status, especially in angina stability (40.5 ± 34.6. Nested regressions indicated stable angina-specific health status explained most of the variation in HRQoL, among which disease perception, physical limitation, and angina stability were the strongest predictors. More physical exercise and better sleep were positively related with HRQoL. CONCLUSIONS: Compared to the general population, stable angina patients were associated with lower HRQoL and lower health utility scores, which were largely impacted by clinical symptoms

  11. SAFETY AND EFFICACY OF BETA-BLOCKERS IN THE TREATMENT OF STABLE ANGINA-PECTORIS

    NARCIS (Netherlands)

    DEMUINCK, ED; LIE, KI

    1990-01-01

    In stable exercise-induced angina pectoris, beta-blockers exert their beneficial effects mainly through a reduction in heart rate, blood pressure, and contractility. Additional beneficial effects are an improvement in myocardial oxygen supply through a redistribution of coronary flow, a lengthening

  12. Spinal cord stimulation in chronic intractable angina pectoris : A randomized, controlled efficacy study

    NARCIS (Netherlands)

    Hautvast, RWM; DeJongste, MJL; Staal, MJ; van Gilst, WH; Lie, KI

    1998-01-01

    Background Spinel cord stimulation is known to be a successful treatment for chronic intractable angina pectoris. its effect may be anti-ischemic. It is uncertain if the clinical effect is partly caused by a placebo effect of surgery For implantation of a stimulator. In this study, clinical efficacy

  13. Angina pectoris refractory for conventional therapy - Is neurostimulation a possible alternative treatment?

    NARCIS (Netherlands)

    Hautvast, RWM; DeJongste, MJL; TerHorst, GJ; Blanksma, PK; Lie, KI

    1996-01-01

    The treatment of angina pectoris as a symptom of coronary artery disease usually is focused on restoring the balance between oxygen demand and supply of the myocardium by administration of drugs interfering in heart rate, cardiac pre- and afterload, and coronary vascular tone. For nonresponders to d

  14. Spinal cord stimulation for refractory angina in patients implanted with cardioverter defibrillators: five case reports

    DEFF Research Database (Denmark)

    Enggaard, Thomas P; Andersen, Claus; Scherer, Christian

    2010-01-01

    Patients implanted with a cardioverter defibrillator (ICD) who are suffering from refractory angina pectoris could benefit from spinal cord stimulation (SCS) due to the well-documented pain relieving effect. However, the combined treatment remains controversial. The aim of the study is to report ...

  15. Norma Primaria de calidad del aire AIR QUALITY STANDARD

    Directory of Open Access Journals (Sweden)

    PATRICIA MATUS C.

    2002-04-01

    Full Text Available Las normas primarias de calidad del aire tienen por finalidad proteger la salud de la población de la contaminación atmosférica. Ellas establecen un nivel de riesgo socialmente aceptado. Este artículo describe los antecedentes considerados durante el proceso de actualización de la regulación vigente en Chile. Detalla conceptos sobre la calidad del aire, describe los efectos en la salud de los contaminantes, y el procedimiento seguido para fijar los nuevos estándares Finaliza enumerando la norma primaria de calidad del aire, sus valores y los limites definidos para ser considerados en el ámbito de la gestión de los episodios críticos o de alta contaminaciónThe main purpose of air quality standards is to protect people health from air pollution. They establish a socially accepted level of risk. This article describes the background information considered during the process for updating the current Chilean regulation. Concepts about quality of air, and the effects of the pollutants on the health are described. The procedure followed to fix the new standards is detailed. Finally we state the primary air quality norm, its values as well as the critical limits in order to control critical events of high air pollution

  16. Reconocimiento a la Atención Primaria de Salud

    Directory of Open Access Journals (Sweden)

    Elso Manuel Cruz Cruz

    2014-08-01

    Full Text Available El presente número de nuestra revista constituye un reconocimiento necesario a la Atención Primaria de Salud (APS, estandarte del sistema de salud cubano, referente a nivel mundial. Son muchos los disímiles trabajos que se realizan desde la APS, imposibles de quedar ejemplificados en el muy limitado espacio que ofrece un número de la revista. Esta edición es sin dudas, especial, para ello se han escogido los resultados investigativos de variados trabajos, realizados desde la perspectiva de diferentes especialidades médicas, en diferentes escenarios, incluida la colaboración médica con países hermanos, pero todos con el denominador común de tributar a la Atención Primaria de Salud. Esperamos que estos artículos aporten relevantes conocimientos a nuestros lectores y se conviertan en referentes de sus trabajos investigativos. El número se confeccionó en los días que ambientaban el desarrollo de la Jornada Científica Provincial de Medicina Familiar, espacio de socialización de resultados científicos obtenidos en la APS. El comité editorial de la revista participó en las sesiones de trabajo del evento, reconociendo la calidad en el desarrollo del mismo y quedando en espera de que muchos de esos trabajos originales se divulguen a la comunidad en forma de artículos científicos

  17. Elecciones primarias abiertas en el Partido Socialista Francés 2011: votan afiliados y simpatizantes.

    OpenAIRE

    Sanz Díaz, Benito (1949-)

    2014-01-01

    Elecciones primarias abiertas en el Partido Socialista Francés. 2011 1.- El modelo francés de 2011. Primarias a la francesa: votan afiliados y simpatizantes. 2.- Una experiencia inédita en Francia: los socialistas abren la elección de su candidato a la Presidencia de la Republica a los simpatizantes de la izquierda. Octubre de 2011. 3.- Los candidatos. 4.-Riesgos. Participación y voto adversario. 5.- ¿Quien podía votar en las primarias? Participar por un euro y adherirse a lo...

  18. Los médicos de Atención Primaria ante la Salud Mental.

    OpenAIRE

    C Camps García; Cristina Gisbert; Rosa Gutiérrez; José Francisco Montilla García

    1995-01-01

    Se exponen las conclusiones de una encuesta de diseño propio realizada a los médicos de Atención Primaria pertenecientes a los centros de salud del área 10 de Madrid. Evaluamos aspectos tales como la relación médico-paciente y sus dificultades, la coordinación entre salud mental y atención primaria, la detección de los trastornos mentales, y las actitudes del médico de atención primaria acerca de la salud mental.

  19. Manejo de la angina refractaria con estimulación eléctrica espinal: revisión de la literatura Treatment of refractory chest angina with spinal electrical stimulator: literature review

    OpenAIRE

    Omar F Gomezese; Paola Aranda; Luis E Echeverría; José F Saibi; Jaime Calderón; Juan G Barrera

    2008-01-01

    Justificación: existe un grupo de pacientes con angina de pecho crónica refractaria, que no son candidatos a revascularización quirúrgica o percutánea y que a pesar de recibir un manejo médico óptimo, aún experimentan severos episodios de angina. El estimulador eléctrico espinal es un neuromodulador que se emplea como alternativa de manejo en estos pacientes. Objetivos: se realizó una revisión sobre estimulación eléctrica espinal en el manejo de la angina, su mecanismo de acción, sus benefici...

  20. Evaluation of coronary hemodynamics and exercise sup 201 Tl-myocardial scintigraphy in patients with vasospastic angina

    Energy Technology Data Exchange (ETDEWEB)

    Matsumura, Kentaro; Nakase, Emiko; Haiyama, Tohru; Hasegawa, Akira; Saito, Takayuki (Kyoto Minami Hospital (Japan))

    1992-05-01

    To clarify the coronary hemodynamics and myocardial perfusion in patients with vasospastic angina, we performed exercise {sup 201}Tl-myocardial scintigraphy (planar and SPECT) in 72 patients and left coronary digital subtraction angiography (DSA) in 37 patients without significant organic coronary artery stenosis. Coronary artery spasm was documented by coronary angiography in all patients. Fifty-four patients (75%) developed exercise-induced {sup 201}Tl-myocardial perfusion defect on SPECT. {sup 201}Tl pulmonary uptake (L/H) was significantly increased in patients with vasospastic angina. Especially, L/H was higher in patients with multiple small perfusion defect on {sup 201}Tl-SPECT, so that exercise-induced left ventricular dysfunction existed in patients with vasospastic angina and especially in cases of multiple small perfusion defect on {sup 201}Tl-SPECT. The left coronary circulation time (CCT) was prolonged in patients with vasospastic angina. The mechanism of prolonged CCT is still unknown, but we suspected that prolonged CCT was induced by increased peripheral coronary vascular resistance in patients with vasospastic angina. It was concluded that the peripheral coronary circulation was disturbed in patients with vasospastic angina, but its abnormal coronary circulation had no relation to location of spasm-induced vessels. We concluded that impaired coronary microcirculation was taken a part of pathophysiology in vasospastic angina. (author).

  1. Serial thallium-201 imaging at rest in patients with unstable and stable angina pectoris: relationship of myocardial perfusion at rest to presenting clinical syndrome

    International Nuclear Information System (INIS)

    In order to determine whether there are differences in myocardial perfusion at rest among patients with various unstable and stable angina syndromes, serial thallium-201 imaging was performed at rest in 19 patients presenting with rapidly worsening exertional angina (unstable angina, group A), 12 patients with rest angina alone without exertional symptoms (unstable angina, group B), and 34 patients with chronic stable angina. No patient had an episode of angina within 4 hours of study. Nineteen of 19 (100%) patients in group A demonstrated transient defects compared to only 3 of 12 (25%) patients in group B (p less than 0.0001) and 4 of 34 (12%) stable angina patients (p less than 0.0001). The majority of zones demonstrating transient defects in group A were associated with hypokinesis of the corresponding left ventriculogram segment without associated ECG evidence of previous infarction. There were no significant differences in the frequency of persistent thallium defects, severity of angiographic coronary artery disease, or frequency of regional wall motion abnormalities of myocardial segments supplied by stenotic coronary arteries among the three groups of patients. Transient defects have been shown to reflect reduction in regional coronary blood flow to viable myocardium. Therefore, we conclude that regional resting hypoperfusion of viable myocardium is far more common in patients with exertional unstable angina symptoms than in patients with rest angina alone or chronic stable angina

  2. Transcoronary sinus administration of autologous bone marrow in patients with chronic refractory stable angina

    International Nuclear Information System (INIS)

    Purpose: Based on our preclinic studies with autologous unfractionated bone marrow (AUBM) via coronary sinus with transitory occlusion, a clinic study in patients with chronic stable angina was designed. The objectives were to evaluate safety, tolerance and feasibility. Methods and materials: A multicenter prospective study with inclusion and exclusion criteria defined by an Independent Clinical Committee was carried out. Fourteen patients underwent transcoronary sinus administration of freshly aspirated and filtered AUBM (60-120 ml). Safety and tolerance were evaluated. Feasibility was evaluated with Seattle Angina Questionnaire (SAQ), Canadian Cardiovascular Society (CCS) angina classification (baseline-Day 180), myocardial perfusion (baseline-Day 90) with independent core laboratory and coronary angiography (baseline and Day 30). Results: There were no changes in the safety and tolerance parameters. Preliminary clinical efficacy at Day 180 disclosed a significant improvement of 38%, evaluated by the SAQ. The CCS angina classification shows that the mean angina class was 3.0±0.55 at baseline and improved to 2.0±0.00 at Day 180 (P<.001). Semiquantitative radionuclide perfusion imaging (core lab) showed a significant improvement at Day 90 in 13/14 patients, with a mean improvement of 24% at rest (P<.01) and 33% at stress (P<.05). Coronary angiography showed more collateral vessels in 9/14 patients. Conclusions: We can conclude that AUBM via coronary sinus with transitory occlusion is tolerable and safe. Significant improvement in the myocardial perfusion at Day 90 and in the quality of life at Day 180 was observed

  3. Erhöhter oxidativer Streß bei Patienten mit instabiler Angina pectoris

    Directory of Open Access Journals (Sweden)

    Bodlaj G

    1998-01-01

    Full Text Available Die instabile Angina pectoris führt oft zum akuten Myokardinfarkt. Da die Lipid-Peroxidation im Verdacht steht, chronische und akute Ereignisse der Atherosklerose und der koronaren Herzkrankheit zu fördern, untersuchten wir die Lipid-Peroxidations-Parameter und alpha-Toco-pherol-Spiegel bei 100 KHK-Patienten und verglichen sie mit denen einer entprechenden Kontrollgruppe. 50 konsekutive Patienten mit stabiler Angina pectoris (SAP und 50 konsekutive Patienten mit instabiler Angina pectoris (IAP wurden untersucht und mit 100 klinisch gesunden Personen verglichen. Zusätzlich zur herkömmlichen Lipid- und Lipoprotein-Analyse wurden die Lipid-Peroxidations-Produkte als Hydroperoxide und Thiobarbituric acid reactive substances (TBARS gemessen. Die konjugierten Diene wurden nur bei den Patienten bestimmt. Da alpha-Tocopherol eines der wichtigsten Antioxidantien ist, wurde es ebenfalls quantifiziert. Wie erwartet hatten die Patienten wesentlich höhere Cholesterin-, Triglyzerid-, LDL-C- und Lp(a-Spiegel und niedrigere HDL-C-Spiegel als die Kontrollgruppe. Als die Patienten in Gruppen mit stabiler und instabiler Angina pectoris geteilt wurden, waren Peroxide und TBARS in der letzteren Gruppe wesentlich höher als bei den anderen Patienten und der Kontrollgruppe. Auch konjugierte Diene waren eindeutig höher bei den Patienten mit instabiler Angina pectoris. Der alpha-Tocopherol-Gesamtspiegel war in allen 3 Gruppen vergleichbar, aber der alpha-Tocopherol-Gehalt pro LDL-Partikel war bei den Patienten mit IAP am niedrigsten, gefolgt von denen mit SAP und der Kontrollgruppe. Wir schließen daraus, daß die Lipid-Peroxidations-Parameter bei Patienten mit IAP erhöht sind und SAP-Patienten von IAP-Patienten unterscheiden.

  4. VEGF 165 Gene Therapy for Patients with Refractory Angina: Mobilization of Endothelial Progenitor Cells

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, Clarissa G. [Instituto de Cardiologia/Fundação Universitária de Cardiologia - Programa de Pós Graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS (Brazil); Duke University Medical Center, Durham, North Carolina (United States); Plentz, Rodrigo D.M. [Instituto de Cardiologia/Fundação Universitária de Cardiologia - Programa de Pós Graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS (Brazil); Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS (Brazil); Dipp, Thiago [Instituto de Cardiologia/Fundação Universitária de Cardiologia - Programa de Pós Graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS (Brazil); Salles, Felipe B. [Instituto de Cardiologia/Fundação Universitária de Cardiologia - Programa de Pós Graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS (Brazil); Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS (Brazil); Giusti, Imarilde I.; Sant' Anna, Roberto T.; Eibel, Bruna; Nesralla, Ivo A.; Markoski, Melissa [Instituto de Cardiologia/Fundação Universitária de Cardiologia - Programa de Pós Graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS (Brazil); Beyer, Nance N. [Instituto de Cardiologia/Fundação Universitária de Cardiologia - Programa de Pós Graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS (Brazil); Universidade Federal do Rio Grande do Sul, Porto Alegre, RS (Brazil); Kalil, Renato A. K., E-mail: kalil.pesquisa@gmail.com [Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS (Brazil)

    2013-08-15

    Vascular endothelial growth factor (VEGF) induces mobilization of endothelial progenitor cells (EPCs) with the capacity for proliferation and differentiation into mature endothelial cells, thus contributing to the angiogenic process. We sought to assess the behavior of EPCs in patients with ischemic heart disease and refractory angina who received an intramyocardial injections of 2000 µg of VEGF 165 as the sole therapy. The study was a subanalysis of a clinical trial. Patients with advanced ischemic heart disease and refractory angina were assessed for eligibility. Inclusion criteria were as follows: signs and symptoms of angina and/or heart failure despite maximum medical treatment and a myocardial ischemic area of at least 5% as assessed by single-photon emission computed tomography (SPECT). Exclusion criteria were as follows: age > 65 years, left ventricular ejection fraction < 25%, and a diagnosis of cancer. Patients whose EPC levels were assessed were included. The intervention was 2000 µg of VEGF 165 plasmid injected into the ischemic myocardium. The frequency of CD34+/KDR+ cells was analyzed by flow cytometry before and 3, 9, and 27 days after the intervention. A total of 9 patients were included, 8 males, mean age 59.4 years, mean left ventricular ejection fraction of 59.3% and predominant class III angina. The number of EPCs on day 3 was significantly higher than that at baseline (p = 0.03); however, that on days 9{sup th} and 27{sup th} was comparable to that at baseline. We identified a transient mobilization of EPCs, which peaked on the 3th day after VEGF 165 gene therapy in patients with refractory angina and returned to near baseline levels on 9{sup th} and 27{sup th}days.

  5. Immediate and long-term clinical outcome after spinal cord stimulation for refractory stable angina pectoris.

    Science.gov (United States)

    Di Pede, Francesco; Lanza, Gaetano Antonio; Zuin, Guerrino; Alfieri, Ottavio; Rapati, Massimo; Romanò, Massimo; Circo, Antonio; Cardano, Paola; Bellocci, Fulvio; Santini, Massimo; Maseri, Attilio

    2003-04-15

    The treatment of patients with angina pectoris refractory to medical therapy and unsuitable for revascularization procedures has yet not been well standardized. Previous retrospective studies and small prospective studies have suggested beneficial effects of spinal cord stimulation (SCS) in these patients. We created a Prospective Italian Registry of SCS to evaluate the short- and long-term clinical outcome of patients who underwent SCS device implantation because of severe refractory angina pectoris. Overall, 104 patients were enrolled in the registry (70 men, aged 68 +/- 17 years), most of whom (83%) had severe coronary artery disease. Average follow-up was 13.2 +/- 8 months. Overall, 17 patients (16%) died, 8 (8%) due to cardiac death. Among clinical variables, only age was found to be significantly associated both with total mortality (p = 0.04) and cardiac mortality (p = 0.02) on Cox regression analysis. A significant improvement of anginal symptoms (> or =50% reduction of weekly anginal episodes, compared with baseline) occurred in 73% of patients, and Canadian Cardiovascular Society angina class improved by > or =1 class in 80% and by > or =2 classes in 42% of patients, with a relevant reduction in the rate of hospital admission and days spent in the hospital because of angina (p <0.0001 for both). No life-threatening or clinically serious complications were observed. The most frequent side effect consisted of superficial infections, either at the site of puncture of electrode insertion or of the abdominal pocket, which occurred in 6 patients. In conclusion, our prospective data point out that SCS can be performed safely and is associated with a sustained improvement of anginal symptoms in a relevant number of patients with refractory stable angina pectoris. PMID:12686334

  6. VEGF 165 Gene Therapy for Patients with Refractory Angina: Mobilization of Endothelial Progenitor Cells

    International Nuclear Information System (INIS)

    Vascular endothelial growth factor (VEGF) induces mobilization of endothelial progenitor cells (EPCs) with the capacity for proliferation and differentiation into mature endothelial cells, thus contributing to the angiogenic process. We sought to assess the behavior of EPCs in patients with ischemic heart disease and refractory angina who received an intramyocardial injections of 2000 µg of VEGF 165 as the sole therapy. The study was a subanalysis of a clinical trial. Patients with advanced ischemic heart disease and refractory angina were assessed for eligibility. Inclusion criteria were as follows: signs and symptoms of angina and/or heart failure despite maximum medical treatment and a myocardial ischemic area of at least 5% as assessed by single-photon emission computed tomography (SPECT). Exclusion criteria were as follows: age > 65 years, left ventricular ejection fraction < 25%, and a diagnosis of cancer. Patients whose EPC levels were assessed were included. The intervention was 2000 µg of VEGF 165 plasmid injected into the ischemic myocardium. The frequency of CD34+/KDR+ cells was analyzed by flow cytometry before and 3, 9, and 27 days after the intervention. A total of 9 patients were included, 8 males, mean age 59.4 years, mean left ventricular ejection fraction of 59.3% and predominant class III angina. The number of EPCs on day 3 was significantly higher than that at baseline (p = 0.03); however, that on days 9th and 27th was comparable to that at baseline. We identified a transient mobilization of EPCs, which peaked on the 3th day after VEGF 165 gene therapy in patients with refractory angina and returned to near baseline levels on 9th and 27thdays

  7. Ranolazine for the treatment of chronic stable angina: a cost-effectiveness analysis from the UK perspective

    OpenAIRE

    Coleman, Craig I.; Freemantle, Nick; Kohn, Christine G

    2015-01-01

    Objectives To estimate the cost-effectiveness of ranolazine when added to standard-of-care (SoC) antianginals compared with SoC alone in patients with stable coronary disease experiencing ≥3 attacks/week. Setting An economic model utilising a UK health system perspective, a 1-month cycle-length and a 1-year time horizon. Participants Patients with stable coronary disease experiencing ≥3 attacks/week starting in 1 of 4 angina frequency health states based on Seattle Angina Questionnaire Angina...

  8. Criptococosis cutánea primaria en paciente inmunocompetente.

    Science.gov (United States)

    Osorio, Igor Vázquez; García-Rodiño, Sara; Rodríguez-Rodríguez, Marta; Labandeira, Javier; Suárez-Peñaranda, José Manuel; Sánchez-Aguilar, MDolores; Vázquez-Veiga, Hugo

    2016-01-01

    La criptococosis cutánea es una micosis propia de pacientes inmunodeprimidos, sobre todo aquellos con infección por el virusde la inmunodeficiencia humana (VIH). Sin embargo, existen casos infrecuentes de criptococosis cutánea en pacientes inmunocompetentes, que suelen simular otras dermatosis, lo que retrasa su diagnóstico y tratamiento. Presentamos el caso de un varón pluripatológico de 79 años, con úlceras dolorosas en dorso de mano derecha que no respondían a tratamientos tópicos. A través del estudio histopatológico y micológico se alcanzó el diagnóstico de criptococosis cutánea primaria, lográndose la remisión de las lesiones tras 6 meses de tratamiento con fluconazol. PMID:27617525

  9. Asma bronquial. Atención primaria de salud

    Directory of Open Access Journals (Sweden)

    Reinaldo Pino Blanco

    2010-12-01

    Full Text Available El siguiente trabajo define las pautas a seguir en la atención primaria de salud para logran un adecuado seguimiento y control de los pacientes que sufren enfermedades respiratorias crónicas y en particular el asma bronquial. Se realiza una revisión profunda de las principales guías para el manejo de la enfermedad, así como las mejores evidencias publicadas hasta la fecha.This paper sets out the guidelines in the primary health care to achieve an adequate monitoring and control of patients suffering from chronic respiratory diseases including bronchial asthma. A systematic review on the main guidelines to handle this disease and the best evidence published to this day are presented.

  10. Effects of preinfarction angina on no-reflow phenomenon after percutaneous coronary intervention in patients with acute myocardial infarction

    Institute of Scientific and Technical Information of China (English)

    王荣英

    2003-01-01

    Effects of preinfarction angina on no-reflow phenomenon after percutaneous coronary intervention in patients with acute myocardial infarction@王荣英$河北医科大学第二医院!石家庄050000 0311-70469016011

  11. Case management does not decrease mortality of patients with myocardial infarction or unstable angina: Evidence from a systematic review

    Directory of Open Access Journals (Sweden)

    Li-Juan Yi

    2016-06-01

    Conclusion: Case management is not beneficial to all-cause mortality after myocardial infarction or unstable angina compared to routine care. Additional, prospective RCTs of high quality and large scale are warranted to verify these results.

  12. PRESENTACIÓN DE UN CASO CON SÍNDROME X O ANGINA MICROVASCULAR / Report of a case with cardiac syndrome X or microvascular angina

    Directory of Open Access Journals (Sweden)

    Dayan A. García Cuesta

    2013-04-01

    Full Text Available Resumen: El término síndrome X o angina microvascular se emplea habitualmente para definir a un grupo de pacientes que presentan dolor torácico característico, depresión del segmento ST durante el esfuerzo y arterias coronarias angiográficamente normales. Muchos datos apuntan a un posible origen isquémico de los síntomas. Es más frecuente en mujeres y en casi el 50 % de ellas, el dolor anginoso se atribuye específicamente a cambios en la microvasculatura coronaria. Debido a que el pronóstico no es tan benigno como se creía hace años, en pacientes con angina y coronarias epicárdicas normales, se impone una evaluación clínica (incluyendo un cuidadoso análisis de los factores de riesgo e imagenológica, con el propósito de detectar isquemia funcionalmente significativa. La enfermedad coronaria microvascular es, por tanto, una enfermedad que requiere atención por parte del médico de asistencia. En este artículo se presenta una paciente con este diagnóstico, y se muestran las imágenes electrocardiográficas, ecocardiográfica, ergométricas y angiográficas. / Abstract: The term cardiac syndrome X or microvascular angina is commonly used to describe a group of patients who show a typical chest pain, ST segment depression during exercise and angiographically normal coronary arteries. Many data suggest the symptoms may have an ischemic origin. It is more common in women, and, in almost 50% of them, anginal pain is specifically attributed to changes in the coronary microvasculature. The prognosis is not as benign as it was believed for years; therefore, in patients with angina and a normal epicardial coronary, a clinical and imaging assessment is necessary (including a careful analysis of risk factors in order to detect a functionally significant ischemia. Therefore, coronary microvascular disease is a condition that requires attention by the attending physician. A patient with this diagnosis is reported in this article, and

  13. Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina. Trimetazidine European Multicenter Study Group.

    OpenAIRE

    Detry, J M; Sellier, P; Pennaforte, S; D. Cokkinos; Dargie, H; Mathes, P

    1994-01-01

    1. Trimetazidine has a direct anti-ischaemic effect on the myocardium without altering the rate x pressure product or coronary blood flow. 2. The effects of trimetazidine (20 mg three times daily) were compared with those of propranolol (40 mg three times daily) in a double-blind parallel group multicentre study in 149 men with stable angina. 3. Reproducibility of exercise performance was verified during a 3 week run-in placebo washout period. All patients had > 1 mm ST-depression on exercise...

  14. Predictor value of some clinical-biological parameters for the onset of depressive disorder in elderly patients with unstable angina

    OpenAIRE

    Cristina Moşuţan; George Săraci; Caius R. Duncea

    2012-01-01

    Abstract. Objective: To evaluate the potential predictor value of some parameters for the onset of depression after an episode of unstableangina in elderly. Material and Methods: We included 103 elderly patients who suffered an acute unstable angina episode. Clinical, laband imagistic data was recorded in the first week after admittance. Six month after unstable angina episode, patients were evaluated for thepresence of depression. Results: Univariate analysis showed statistically significant...

  15. Use of myocardial perfusion imaging to predict the effectiveness of coronary revascularisation in patients with stable angina pectoris

    International Nuclear Information System (INIS)

    Coronary revascularisation is the treatment of choice in patients with stable angina who have significant stenoses. From a pathophysiological point of view, however, mitigation of angina is to be expected only in the presence of reversible ischaemia. Therefore it was the aim of this study to examine the effect of revascularisation on stable angina in relation to the myocardial perfusion imaging (MPI) pattern prior to intervention. Three hundred and eighty-four patients (58.0±8.8 years) referred for angiography underwent MPI. Prior to MPI and at 2-year follow-up, patients were classified as having typical angina, atypical angina, non-cardiac chest pain or no pain, and the severity of chest pain was graded according to the Canadian Cardiovascular Society (CCS) criteria. The patients themselves estimated their pain on a visual analogue scale. Management was based on symptoms and angiographic findings, since the results of MPI were not communicated. Among the 240 patients who were not revascularised, 79% had typical or atypical angina at study entrance versus 40% at follow-up. In comparison, 93% of the 144 revascularised patients had typical or atypical angina before intervention versus only 36% at follow-up. This additional advantage of invasive therapy was present only in patients with reversible defects; revascularisation had no additional effect in patients with normal perfusion or irreversible defects. Similarly, additional, significant reductions in CCS class and visual analogue score were observed exclusively in patients with reversible defects. In patients referred for coronary angiography owing to known or suspected stable angina, revascularisation was significantly more effective than medical treatment exclusively in patients with reversible ischaemia. (orig.)

  16. Use of myocardial perfusion imaging to predict the effectiveness of coronary revascularisation in patients with stable angina pectoris

    Energy Technology Data Exchange (ETDEWEB)

    Johansen, Allan [Odense University Hospital, Department of Clinical Physiology and Nuclear Medicine, Odense (Denmark); Odense University Hospital, Department of Nuclear Medicine, Odense (Denmark); Hoeilund-Carlsen, Poul Flemming; Moeldrup, Mette [Odense University Hospital, Department of Clinical Physiology and Nuclear Medicine, Odense (Denmark); Christensen, Henrik Wulff [Nordic Institute of Chiropractic and Clinical Biomechanics, Odense (Denmark); Vach, Werner [University of Southern Denmark, Department of Statistics, Odense (Denmark); Haghfelt, Torben [Odense University Hospital, Department of Cardiology, Odense (Denmark)

    2005-12-01

    Coronary revascularisation is the treatment of choice in patients with stable angina who have significant stenoses. From a pathophysiological point of view, however, mitigation of angina is to be expected only in the presence of reversible ischaemia. Therefore it was the aim of this study to examine the effect of revascularisation on stable angina in relation to the myocardial perfusion imaging (MPI) pattern prior to intervention. Three hundred and eighty-four patients (58.0{+-}8.8 years) referred for angiography underwent MPI. Prior to MPI and at 2-year follow-up, patients were classified as having typical angina, atypical angina, non-cardiac chest pain or no pain, and the severity of chest pain was graded according to the Canadian Cardiovascular Society (CCS) criteria. The patients themselves estimated their pain on a visual analogue scale. Management was based on symptoms and angiographic findings, since the results of MPI were not communicated. Among the 240 patients who were not revascularised, 79% had typical or atypical angina at study entrance versus 40% at follow-up. In comparison, 93% of the 144 revascularised patients had typical or atypical angina before intervention versus only 36% at follow-up. This additional advantage of invasive therapy was present only in patients with reversible defects; revascularisation had no additional effect in patients with normal perfusion or irreversible defects. Similarly, additional, significant reductions in CCS class and visual analogue score were observed exclusively in patients with reversible defects. In patients referred for coronary angiography owing to known or suspected stable angina, revascularisation was significantly more effective than medical treatment exclusively in patients with reversible ischaemia. (orig.)

  17. Xuesaitong Soft Capsule (Chinese Patent Medicine) for the Treatment of Unstable Angina Pectoris: A Meta-Analysis and Systematic Review

    OpenAIRE

    Xiaochen Yang; Xingjiang Xiong; Heran Wang; Guoyan Yang; Jie Wang

    2013-01-01

    Objective. To provide a systematic review to evaluate the effectiveness and safety of Xuesaitong soft capsule (XST) in treating unstable angina (UA). Methods. An extensive search of 6 medical databases was performed up to August 2013. Randomized controlled trials (RCTs) involving XST alone or combined with conventional drugs versus conventional drugs were included. A meta-analysis of reduction of angina symptoms and electrocardiogram (ECG) improvement was performed to evaluate the effects of ...

  18. Association of Low Levels of Vitamin D with Chronic Stable Angina: A Prospective Case-Control Study

    OpenAIRE

    Ab Hameed Raina; Mohammad Sultan Allai; Zafar Amin Shah; Khalid Hamid Changal; Manzoor Ahmad Raina; Fayaz Ahmad Bhat

    2016-01-01

    Background: Coronary artery disease (CAD) is a major cause of death and disability in developed countries. Chronic stable angina is the initial manifestation of CAD in approximately 50% of the patients. Recent evidence suggests that vitamin D is crucial for cardiovascular health. The prevalence of vitamin D deficiency in our region is 83%. A low level of vitamin D is associated with chronic stable angina. Aim: This study was aimed at supporting or refuting this hypothesis in our population. M...

  19. Severe Life Threatening Maxillofacial Infection in Pregnancy Presented as Ludwig's Angina

    Directory of Open Access Journals (Sweden)

    M. Franklin Dolwick

    2006-08-01

    Full Text Available Background. Ludwig's angina is a rapidly spreading cellulitis that may produce upper airway obstruction often leading to death. There is very little published information regarding this condition in the pregnant patient. Case. A 24-year old black female was admitted at 26 weeks gestation with tooth pain, submandibular swelling, severe trismus, and dysphagea, consistent with Ludwig's angina. Her treatment included emergent tracheostomy, incision and drainage of associated spaces, teeth extraction, and antibiotic therapy. Conclusions. During a life threatening infectious situation such as the one described, risks of maternal and fetal morbidity include both septicemia and asphyxia. Furthermore, the healthcare provider must consider the risks that the condition and the possible treatments may cause the mother and her unborn child.

  20. Chest pain and angina pectoris - or the ugly swan and the beautiful duckling

    Science.gov (United States)

    van Tellingen, C.

    2010-01-01

    The original description of Heberden’s angina pectoris is put forward to stress the importance of proper history-taking in identifying patients. In a market-driven approach to improve cost-effectiveness in healthcare, angina pectoris as an entity seems stripped to its bare minimum: chest and pain. The diagnostic yield of exercise testing, however, depends on the pre-test likelihood of disease and therefore knowledge of its clinical utility and pitfalls is essential to refine an initial and subjective diagnosis based on anamnesis. Nowadays chest pain units attempt to improve diagnostic accuracy by submitting all sorts of patients to the (stress) test. In the end protocol-driven policies like these may very well prove to be contraproductive when fundamentals are ignored. (Neth Heart J 2010;18:561–4.) PMID:21113382

  1. ONE CASE REPORT OF ANGINA TONSILLARIS INDUCED MEDIASTINAL ABSCESS AND THORACIC EMPYEMA

    Institute of Scientific and Technical Information of China (English)

    LI Qing-yun; WANG Xi; WAN Huan-ying; DENG Wei-wu

    2009-01-01

    A 27-year-old female patient with mediastinal abscess and thoracic empyema developed from angina tonsillaris was studied clinically on the manifestations, computed tomography (CT) scan, and the treatment process. The patient was admitted to hospital with a history of fever, sore throat, and chest and neck pain. CT showed air and air-fluid levels within mediastinal dense fatty planes that extended from the thoracic inlet to the sub-carinal region and left pleural empyema. She was cured by mediastinal drainage and extensive debridement of the necrotic tissue under operation and broad spectrum antibiotics treatment. Angina tonsillaris induced acute mediastitis and mediastinal abscess is a relatively rare inflammatory pathology but actually a fatal situation for its high mortality rate. CT scanning is extremely useful for early diagnosis and surgical treatment planning. The main treatment is aggressive and adequate surgical drainage of the abscess and intravenous effective antibiotic treatment.

  2. Optimal treatment of chronic angina in patients with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Kaur H

    2014-07-01

    Full Text Available Harjinder Kaur,1 Kully Sandhu,2 Awais Jabbar,3 Azfar G Zaman3,4 1City Hospitals Sunderland, Sunderland, UK; 2University Hospital of North Staffordshire, Stoke-on-Trent, UK; 3Freeman Hospital, Newcastle-upon-Tyne, UK; 4Institute of Cellular Medicine, Newcastle University, Newcastle, UK Abstract: Type 2 diabetes mellitus (T2DM trebles the risk of developing coronary artery disease (CAD; once CAD has developed, the risk of acute coronary syndromes (ACS and clinical risk associated with a coronary event, both double in diabetic patients. Patients with T2DM have more extensive CAD and present at a younger age; therefore, identification and management of chronic angina in these patients presents an opportunity to limit both cardiovascular symptoms and adverse outcomes. This article reviews the role of screening and treatment for chronic angina in patients with T2DM. There is a strong evidence base for modifying lifestyle as a way of reducing adverse cardiovascular outcomes in the diabetic population and this article reviews evidence of lifestyle modification as an important and necessary adjunct to pharmacologic intervention. Management of chronic stable angina is addressed by looking at treatments that reduce ischemic symptoms and those that reduce adverse cardiovascular outcomes. Trials specific to the diabetic population are limited, with information largely obtained from the diabetic subgroup analysis of large intervention trials. The growing diabetic population with increased propensity to cardiovascular disease mandates trials specifically in this patient population. Revascularization in patients with diabetes is associated with more complications than in the non-diabetic population. Recent trials specific to this population suggest surgical revascularization to be associated with better long-term outcomes and therefore, this article reviews the evidence for the optimal mode of revascularization in this population. Keywords: type 2 diabetes

  3. Can music improve the symptoms of stable angina? A randomized controlled trial

    OpenAIRE

    Premadasa Mudunkotuwa; Kumudu Wijewardena; Ruwan Ekanayaka; Samitha Siritunga

    2013-01-01

    Worldwide, the leading cause of death is ischemic heart disease. Other than medical and surgical management, alternative therapy such as relaxing music has been identified as having an impact on reducing morbidity in ischemic heart disease. Although several studies have been conducted to find out the impact of music on pain, anxiety, heart rate and stress in myocardial ischaemia, literature on the long term impact of music on severity of symptoms associated with stable angina is very sparse....

  4. Beneficial effects of intravenous glyceryl trinitrate in a case of Prinzmetal angina.

    OpenAIRE

    Antman, E; Gunther, S.; Barry, W

    1980-01-01

    A case is described of the successful use of intravenous glyceryl trinitrate in controlling ischaemia-induced high-grade ventricular ectopic activity occurring in a patient during a Prinzmetal angina attack. The intravenous form of glyceryl trinitrate is probably more effective than the sublingual form in controlling arrhythmias arising during acute ischaemic episodes because of prompt delivery of the drug to the coronary circulation where vasodilation occurs. In addition,the ability to contr...

  5. Reduced peripheral vascular reactivity in refractory angina pectoris: Effect of enhanced external counterpulsation

    Institute of Scientific and Technical Information of China (English)

    Susanne M Bondesson; Marie-Louise Edvinsson; Thomas Pettersson; Lars Edvinsson

    2011-01-01

    Objective To examine if the skin microvascular bed is altered and can be modified by enhanced external counterpulsation (EECP) in patients with chronic refractory angina.Methods Twenty patients diagnosed with refractory angina were divided into EECP (n =10) or no EECP (n =10) groups.The data were compared to matched healthy subjects (n =20).The cutaneous forearm microvascular blood flow was measured by Laser-Doppler flowmetry.The vascular responsiveness to iontophoretic administration of acetylcholine (ACh),sodium nitroprusside (SNP) and local skin warming were studied.Measurements of Canadian Cardiovascular Society (CCS)-class,blood pressure and plasma samples were registered.Results EECP patients showed reduced CCS-class compared to no EECP (P < 0.05).Both EECP and no EECP (P < 0.05) groups had decreased systolic blood pressure (SBP) as compared to SBP at baseline (P < 0.05).There was no difference in resting blood flow between the two refractory groups at baseline as well as after EECP and seven weeks of follow-up.Responses to heating,the responses to ACh and SNP in the cutaneous microcirculation were lower in both groups of refractory angina patients as compared to healthy subjects (P < 0.05).EECP patients corresponded positively to the treatment shown by reduced plasma level of soluble interleukin-2 receptor and CCS-class.Conclusions Refractory angina patients have reduced responsiveness in their cutaneous microcirculation to ACh,SNP and heat compared to healthy subjects.Although EECP reduced the CCS-class,this effect was not associated with improvements in responsiveness of the cutaneous microcirculation.

  6. Prognostic implications of exercise induced and ambulatory ischemia in patients with stable angina pectoris

    OpenAIRE

    Forslund, Lennart

    1999-01-01

    Results from exercise testing and ambulatory ECG registration were studied in 809 patients with stable angina pectoris; special attention was paid to signs of ischemia during both tests. Autonomic nervous system activity was investigated by measurements of heart rate variability (HRV) and catecholamines in plasma and urine. At baseline, the patients were compared with 50 age and sex matched controls. Prognostic implications of HRV, catecholamine levels, signs of ischemia dur...

  7. Treatment of Refractory Angina with Peripheral Blood-derived Stem Cell Using the Transendocardial Injection Route

    OpenAIRE

    Juan Jose González Ferrer; Pilar Jiménez-Quevedo; Maria del Trigo

    2011-01-01

    Despite the development of new anti-ischemic drugs and the improvements in revascularisation techniques, a substantial proportion of patients with ischemic heart disease remain symptomatic with severe debilitating angina. The major aim of therapy for these patients should be aggressive modification of risk factors and optimising medical and interventional treatment. Nevertheless, when disease progresses and standard treatments are not possible, new strategies should be established. In this se...

  8. Extended-release ranolazine: critical evaluation of its use in stable angina

    OpenAIRE

    Melloni C; Newby LK; Truffa AAM

    2011-01-01

    Adriano AM Truffa, L Kristin Newby, Chiara MelloniDuke Clinical Research Institute and Department of Medicine, Duke University Medical Center, Durham, NC, USAAbstract: Coronary heart disease is the major cause of morbidity and mortality throughout the world, and is responsible for approximately one of every six deaths in the US. Angina pectoris is a clinical syndrome characterized by discomfort, typically in the chest, neck, chin, or left arm, induced by physical exertion, emotional stress, o...

  9. ENDOTHELIAL DYSFUNCTION IN STABLE ANGINA AND MYOCARDIAL INFARCTION COMBINED WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

    Directory of Open Access Journals (Sweden)

    M. A. Popova

    2016-02-01

    Full Text Available The research objective is to determine the state of endothelium-dependent and endothelium-independent vasodilatation in patients with coronary heart disease (CHD associated with chronic obstructive pulmonary disease (COPD.Material and methods. In the cross-sectional study included 122 patients with CHD associated with COPD: 68 people of them are patients with stable angina without acute coronary events in history and 54 patients with acute ST segment elevation myocardial infarction (STEMI. Comparison group comprised 53 patients with stable angina and 51 patients after STEMI without concomitant COPD. Patients were included if they met the following inclusion criteria: male, age <60 years, verified forms of CHD (stable angina, STEMI, documented with COPD without exacerbation and forced expiratory volume in 1 second > 30% in the groups with CHD and COPD. Arterial endothelial function was tested with high-resolution ultrasonography: brachial artery diameter was measured at rest, after flow increase (which causes endothelium-dependent dilatation, and after administration of sublingual nitroglycerin (an endothelium-independent dilator.Results. We found that endothelial dysfunction in patients with acute and chronic forms of CHD in combination with COPD are more pronounced than in isolated CHD.Conclusion. Expressed depression functional vascular reserve in patients with CHD associated with COPD, should be taken into account when conducting individualized therapy of these patients.

  10. Efficacy evaluation of fluoxetine combined with conventional drug treatment on unstable angina patients complicated with depression

    Institute of Scientific and Technical Information of China (English)

    Chun-Hua Liao

    2015-01-01

    Objective:To study the efficacy of fluoxetine combined with conventional drug treatment on unstable angina patients complicated with depression. Methods:120 cases of unstable angina patients with depression were randomly divided into two groups. The anti-depression group received fluoxetine combined with conventional drug therapy; the conventional group received conventional drug therapy. Then contents of monoamine neurotransmitters and their metabolites, antioxidants and inflammatory mediators of both groups were compared. Results:Serum monoamine neurotransmitters NE, 5-HT and HA levels of the anti-depression group were higher than those of the conventional group and metabolites 5-HIAA and HVA contents were lower than those of the conventional group; serum SOD, CAT, GSH and HSP-70 contents of the anti-depression group were higher than those of the conventional group, and hs-CRP, MMP9, MCP1 and HMGB1 contents were lower than those of the conventional group. Conclusion:Fluoxetine combined with conventional drug therapy can increase the contents of monoamine neurotransmitters and antioxidants, and reduce oxidative stress response and inflammatory response; it is an ideal method for treating unstable angina complicated with depression.

  11. COMPARISON BETAXOLOL AND METOPROLOL TARTRATE THERAPIES IN PATIENTS WITH ARTERIAL HYPERTENSION ASSOCIATED WITH STABLE ANGINA

    Directory of Open Access Journals (Sweden)

    A. A. Anderzhanova

    2016-01-01

    Full Text Available Aim. To compare antihypertensive, antianginal and antiischemic efficacy of β1-selective adrenoblockers (betaxolol and metoprolol tartrate in patients with arterial hypertension (HT of 1-2 degree associated with stable angina class II.Material and methods. 100 patients (aged 23-66 y.o. with HT associated with stable angina or without angina were involved in the study. Patients were randomized into 2 groups (G1 and G2. G1 patients were treated with betaxolol, and G2 patients – with metoprolol tartrate. Ambulatory BP and electrocardiogram monitoring, exercise stress-test, echocardiography, evaluating of respiratory function, blood analysis was performed initially and in 30 and 90 days of treatment.Results. Target BP level was reached in 44 (88% patients treated with betaxolol (average daily dose 10±4 mg. 34 patients of G1 took 10 mg daily. Target BP level was reached in 41 (82% patients treated with metoprolol tartrate (average daily dose 150±27 mg. 30 patients of G2 took 150 mg daily. Exercise tolerance increased and a number of ischemic ST segment depressions reduced significantly in both groups. There were no significant differences in antihypertensive, antianginal, and antiischemic efficacy between groups.Conclusion. Betaxolol advantage is an ability to maintain target BP level more than 24 hours. A possibility to take betaxolol once a day raises patient’s compliance with therapy.

  12. Extended-release ranolazine: critical evaluation of its use in stable angina

    Directory of Open Access Journals (Sweden)

    Melloni C

    2011-08-01

    Full Text Available Adriano AM Truffa, L Kristin Newby, Chiara MelloniDuke Clinical Research Institute and Department of Medicine, Duke University Medical Center, Durham, NC, USAAbstract: Coronary heart disease is the major cause of morbidity and mortality throughout the world, and is responsible for approximately one of every six deaths in the US. Angina pectoris is a clinical syndrome characterized by discomfort, typically in the chest, neck, chin, or left arm, induced by physical exertion, emotional stress, or cold, and relieved by rest or nitroglycerin. The main goals of treatment of stable angina pectoris are to improve quality of life by reducing the severity and/or frequency of symptoms, to increase functional capacity, and to improve prognosis. Ranolazine is a recently developed antianginal with unique methods of action. In this paper, we review the pharmacology of ranolazine, clinical trials supporting its approval for clinical use, and studies of its quality of life benefits. We conclude that ranolazine has been shown to be a reasonable and safe option for patients who have refractory ischemic symptoms despite the use of standard medications (for example, nitrates, beta-adrenergic receptor antagonists, and calcium channel antagonists for treatment of anginal symptoms, and also provides a modestly improved quality of life.Keywords: ranolazine, coronary heart disease, angina, treatment

  13. The prevalence of angina symptoms and association with cardiovascular risk factors, among rural, urban and rural to urban migrant populations in Peru

    OpenAIRE

    Gilman Robert H; Loret de Mola Christian; Zaman M Justin S; Smeeth Liam; Miranda J Jaime

    2010-01-01

    Abstract Background Rural-to-urban migration in low- and middle-income countries causes an increase in individual cardiovascular risk. Cost-effective interventions at early stages of the natural history of coronary disease such as angina may stem an epidemic of premature coronary deaths in these countries. However, there are few data on the prevalence of angina in developing countries, whilst the understanding the aetiology of angina is complicated by the difficulty in measuring it across dif...

  14. Evaluation of the add-on effect of chinese patent medicine for patients with stable or unstable angina: a systematic review and meta-analysis.

    Science.gov (United States)

    Mao, Chen; Chung, Vincent C H; Yuan, Jin-Qiu; Yu, Yuan-Yuan; Yang, Zu-Yao; Wu, Xin-Yin; Tang, Jin-Ling

    2013-01-01

    Chinese herbal medicine (CHM) has been widely used as an adjunct to western medicine in treating angina in China. We carried out this systematic review to evaluate the effectiveness of CHM on top of western medicine for angina. This meta-analysis included 46 randomized control trials with 4212 patients. For trials that included stable angina patients, the CHM group had significant lower incidence of total heart events (relative risk (RR) = 0.50, 95% confidence interval (CI) 0.33-0.78), myocardial infarction (RR = 0.32, 95% CI 0.14-0.72), heart failure (RR = 0.37, 95% CI 0.15-0.91), and angina (RR = 0.46, 95% CI 0.30-0.71) than that of control group. For trials that included unstable angina patients, CHM led to significantly lower occurrence of total heart events (RR = 0.46, 95% CI 0.32-0.66), myocardial infarction (RR = 0.37, 95% CI 0.26-0.54), and angina (RR = 0.36, 95%CI 0.26-0.51). Likewise, for trials that included stable or unstable angina patients, the rates of myocardial infarction (RR = 0.34, 95% CI 0.17-0.68) and angina (RR = 0.46, 95% CI 0.30-0.70) in CHM group were significantly lower than that in control group. In conclusion, CHM is very likely to be able to improve the survival of angina patients who are already receiving western medicine. PMID:24416066

  15. Five year prognosis in patients with angina identified in primary care: incident cohort study.

    LENUS (Irish Health Repository)

    Buckley, Brian S

    2009-01-01

    OBJECTIVE: To ascertain the risk of acute myocardial infarction, invasive cardiac procedures, and mortality among patients with newly diagnosed angina over five years. DESIGN: Incident cohort study of patients with primary care data linked to secondary care and mortality data. SETTING: 40 primary care practices in Scotland. PARTICIPANTS: 1785 patients with a diagnosis of angina as their first manifestation of ischaemic heart disease, 1 January 1998 to 31 December 2001. MAIN OUTCOME MEASURES: Adjusted hazard ratios for acute myocardial infarction, coronary artery bypass grafting, percutaneous transluminal coronary angioplasty, death from ischaemic heart disease, and all cause mortality, adjusted for demographics, lifestyle risk factors, and comorbidity at cohort entry. RESULTS: Mean age was 62.3 (SD 11.3). Male sex was associated with an increased risk of acute myocardial infarction (hazard ratio 2.01, 95% confidence interval 1.35 to 2.97), death from ischaemic heart disease (2.80, 1.73 to 4.53), and all cause mortality (1.82, 1.33 to 2.49). Increasing age was associated with acute myocardial infarction (1.04, 1.02 to 1.06, per year of age increase), death from ischaemic heart disease (1.09, 1.06 to 1.11, per year of age increase), and all cause mortality (1.09, 1.07 to 1.11, per year of age increase). Smoking was associated with subsequent acute myocardial infarction (1.94, 1.31 to 2.89), death from ischaemic heart disease (2.12, 1.32 to 3.39), and all cause mortality (2.11, 1.52 to 2.95). Obesity was associated with death from ischaemic heart disease (2.01, 1.17 to 3.45) and all cause mortality (2.20, 1.52 to 3.19). Previous stroke was associated with all cause mortality (1.78, 1.13 to 2.80) and chronic kidney disease with death from ischaemic heart disease (5.72, 1.74 to 18.79). Men were more likely than women to have coronary artery bypass grafting or percutaneous transluminal coronary angioplasty after a diagnosis of angina; older people were less likely to

  16. Medida de la eficiencia de la atención primaria en Barcelona incorporando indicadores de calidad

    Directory of Open Access Journals (Sweden)

    José Romano

    2016-09-01

    Conclusiones: Los resultados parecen indicar la conveniencia de incorporar la calidad asistencial como uno de los outputs relevantes a la hora de plantear criterios de racionalización de los servicios en asistencia primaria de salud. Su (no incorporación se encuentra vinculada a diversas concepciones de la atención primaria de salud.

  17. Una propuesta de acercamiento a la literatura en educación primaria utilizando las ilustraciones de Segrelles

    OpenAIRE

    Soler Navarro, Joan Josep

    2011-01-01

    Actividades didácticas realizadas desde la Casa Museo José Segrelles con alumnos de primaria y secundaria con motivo de la conmemoración del 125 aniversario del nacimiento de José Segrelles. Palabras clave: colaboración, educación primaria, educación secundaria, didáctica, museo-

  18. Atención primaria: Una estrategia renovada

    Directory of Open Access Journals (Sweden)

    José A. Serna

    2011-09-01

    Full Text Available Esta revisión profundiza en los cambios establecidos por diferentes estamentos mundiales con respecto al concepto ymodo de implementación de la estrategia de Atención Primaria en Salud (APS originada en Alma-Ata en 1978. Bajacobertura, altos costos, inequidad, utilización inadecuada del talento humano y del recurso tecnológico hicieron imperiosasu actualización. En ella se establecen cuatro pilares fundamentales a introducir en sistemas de salud que tengan como su ejela APS, como el logro de dar cobertura universal a toda la población, brindar una atención médico-paciente centrada en elindividuo, promover unas políticas de salud pública que beneficien a toda la comunidad y ejercer una gobernabilidad nacionalo regional concertada con todos los estamentos que influyan en los determinantes de salud de un individuo y su entorno. Laimplementación de la misma en dichos sistemas de salud dependerá del contexto de cada país y de su tipo de desarrollo ycrecimiento del sector salud

  19. Xuesaitong Soft Capsule (Chinese Patent Medicine for the Treatment of Unstable Angina Pectoris: A Meta-Analysis and Systematic Review

    Directory of Open Access Journals (Sweden)

    Xiaochen Yang

    2013-01-01

    Full Text Available Objective. To provide a systematic review to evaluate the effectiveness and safety of Xuesaitong soft capsule (XST in treating unstable angina (UA. Methods. An extensive search of 6 medical databases was performed up to August 2013. Randomized controlled trials (RCTs involving XST alone or combined with conventional drugs versus conventional drugs were included. A meta-analysis of reduction of angina symptoms and electrocardiogram (ECG improvement was performed to evaluate the effects of XST on UA. Results. After researching, a total of 6 RCTs with 716 participants were included. Our review showed that XST combined with conventional drugs had significant effect on relieving angina symptoms (RR: 1.14 [1.07,1.22]; P=0.0001 and improving ECG (RR: 1.26 [1.12,1.42]; P=0.0001 compared with conventional drugs alone. Conclusions. XST appears to have beneficial effects on improvement of ECG, reduction of angina symptoms, and decreasing the frequency and duration of angina attack in participants with UA. However, the findings should be interpreted with caution due to the poor methodological quality of the included trials.

  20. Xuesaitong soft capsule (chinese patent medicine) for the treatment of unstable angina pectoris: a meta-analysis and systematic review.

    Science.gov (United States)

    Yang, Xiaochen; Xiong, Xingjiang; Wang, Heran; Yang, Guoyan; Wang, Jie

    2013-01-01

    Objective. To provide a systematic review to evaluate the effectiveness and safety of Xuesaitong soft capsule (XST) in treating unstable angina (UA). Methods. An extensive search of 6 medical databases was performed up to August 2013. Randomized controlled trials (RCTs) involving XST alone or combined with conventional drugs versus conventional drugs were included. A meta-analysis of reduction of angina symptoms and electrocardiogram (ECG) improvement was performed to evaluate the effects of XST on UA. Results. After researching, a total of 6 RCTs with 716 participants were included. Our review showed that XST combined with conventional drugs had significant effect on relieving angina symptoms (RR: 1.14 [1.07, 1.22]; P = 0.0001) and improving ECG (RR: 1.26 [1.12, 1.42]; P = 0.0001) compared with conventional drugs alone. Conclusions. XST appears to have beneficial effects on improvement of ECG, reduction of angina symptoms, and decreasing the frequency and duration of angina attack in participants with UA. However, the findings should be interpreted with caution due to the poor methodological quality of the included trials. PMID:24489594

  1. Tratamento de angina mesentérica em pacientes com arterite de Takayasu Treatment of mesenteric angina in patients with Takayasu's arteritis

    Directory of Open Access Journals (Sweden)

    Luana Thayse Barros de Lima

    2011-04-01

    Full Text Available Aarterite de Takayasu (AT é uma doença inflamatória crônica do tecido conectivo, idiopática, que acomete preferencialmente a aorta e seus ramos. A terapêutica utilizada baseia-se sobretudo no uso de corticosteroides e imunossupressores. É relatado o caso de uma paciente, 33 anos, com mal-estar, febre, mialgia, cefaleia intensa, pulsátil, holocraniana, resistente a analgésicos, hipertensão arterial sistêmica de difícil controle, claudicação no membro inferior direito e dor abdominal de forte intensidade, a qual piorava após a alimentação. A angiotomografia revelou aneurisma da aorta ascendente, estenose da artéria ilíaca comum direita, estenose das artérias renais e estenose da artéria mesentérica superior, fato que embasou o diagnóstico de angina mesentérica e a conduta intervencionista através da angioplastia transluminal percutânea múltipla com a colocação de stents.Takayasu's arteritis (TA is an idiopathic chronic inflammatory disease of the connective tissue that affects mainly the aorta and its branches. Treatment is mainly based on corticosteroids and immunosuppressants. We report the case of a 33-year-old female complaining of malaise, fever, myalgia, severe pulsing holocranial headache resistant to analgesics, systemic arterial hypertension hard to control, right lower limb claudication, and severe abdominal pain that worsened after the meals. Angiotomography revealed aneurysm of the ascending aorta, and stenosis of the following vessels: right common iliac artery, renal arteries, and superior mesenteric artery. Those findings supported the diagnosis of mesenteric angina and the interventional approach by use of percutaneous transluminal angioplasty with stent placement.

  2. Esofagitis necrotizante aguda en paciente inestable

    OpenAIRE

    Rodrigo, M.; B.E. Gorraiz; Merino, C.; J. Eguaras; J.M. Elizalde; W. Soler

    2009-01-01

    La esofagitis necrotizante aguda o esófago negro es una afección rara, conocida en la literatura médica desde 1990. Aunque su mecanismo no es del todo conocido, el compromiso isquémico parece ser el factor fisiopatológico fundamental. Cuando la esofagitis necrotizante aguda es un hallazgo en el estudio endoscópico de hemorragia digestiva alta, sin desestabilización hemodinámica, el pronóstico es bueno. Presentamos un caso en el que el diagnóstico de esófago negro fue un mero hallazgo endoscóp...

  3. Esofagitis necrotizante aguda en paciente inestable

    Directory of Open Access Journals (Sweden)

    M. Rodrigo

    2009-04-01

    Full Text Available La esofagitis necrotizante aguda o esófago negro es una afección rara, conocida en la literatura médica desde 1990. Aunque su mecanismo no es del todo conocido, el compromiso isquémico parece ser el factor fisiopatológico fundamental. Cuando la esofagitis necrotizante aguda es un hallazgo en el estudio endoscópico de hemorragia digestiva alta, sin desestabilización hemodinámica, el pronóstico es bueno. Presentamos un caso en el que el diagnóstico de esófago negro fue un mero hallazgo endoscópico, secundario a una situación de inestabilidad hemodinámica subyacente, con resultado fatal.

  4. [The treatment of chronic stable angina with isradipine. A cooperative Latin American study].

    Science.gov (United States)

    Román, O; Alcocer, L; Espinoza, J; Arcos, R; Gómez, G; Mayorga, E; Buzzi, A; Tavella, N; Romero, C; Kuster, F

    1991-04-01

    In order to study the efficacy and tolerance of isradipine, a new Ca++ antagonist for the treatment of stable chronic angina, a multicentric cooperative study was carried out in eight Latin American countries (Argentine, Chile, Colombia, Ecuador, Mexico, Peru, Uruguay and Venezuela), which included 169 patients (60% men and 40% women), average age 62.6 +/- 9.7. Patients with more than 4 biweekly anginal crisis were accepted, with one or more of the following inclusion criteria: coronariographic evidence of obstruction greater than 60% in one or more vessels, IAM history, positive scintigraphy and positive effort test. The trial was single-blind, with placebo during the admission phase (2 weeks) and active treatment for 12 weeks. isradipine was administered in increasing doses of 2.5, 5, and 7 mg thrice a day, according to the presence or absence of anginal crisis. It was observed that the average frequency of weekly pains decreased from 8.2 +/- 7 under placebo to 6.3 +/- 7.5 under isradipine at low doses, and to 2.0 +/- 2.0 (p less than 0.001) under maximum doses. TNT intake decreased parallel also in a significant way. At the end of the trial, 37% of patients had become asymptomatic, and angina had reduced to less than two crisis a week in 33%. A clear relation doses-effect was observed. There was no alteration in laboratory exams neither in ECG. Seven patients had complications derived from the evolutional course of disease (2 IAM, 5 unstable angina and one sudden death). Adverse events were relatively frequent and the majority derived from vasodilator effect (tibial oedema 37%, flushing 17%, headache 23%).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1829846

  5. PHARMACOECONOMIC ASPECTS OF NICOTINE ADDICTION TREATMENT IN PATIENTS WITH ANGINA REQUIRING CARDIAC SURGERY

    Directory of Open Access Journals (Sweden)

    A. V. Rudakova

    2015-12-01

    Full Text Available Smoking is a major risk factor in patients with angina pectoris. Interventions that facilitate the rejection of it are an important part of the treatment. Aim. To analyze the cost effectiveness of the partial agonist of nicotinic receptors, varenicline, in patients with angina who require cardiac interventions. Material and methods. The estimation was conducted using a Markov model based on the results of clinical trials and epidemiological studies. The cost of treatment of complications were calculated on the basis of compulsory medical insurance rates for St. Petersburg in 2011. Results. The varenicline therapy in 70-year-old patients before cardiac surgery reduces hospital mortality at an extremely high cost-effectiveness (the cost of preventing one death - 148.8 thousand rubles. The cost/effectiveness ratio in the analysis for the period of survival of patients in this situation was 31.3 thousand rubles for 1 additional year of life. Life expectancy will be increased by an average of 0.147 years. Analysis for the period of survival of 50-year-old patients has shown that in patients after cardiac surgery cost-effectiveness of varenicline is extremely high (in the analysis from the perspective of the health care system the cost/effectiveness ratio was 36.0 thousand rubles for 1 additional year of life, in the analysis, taking into account the social perspective – 17.9 thousand rubles for 1 additional year of life. Increase in the life expectancy of 50 year-old patients will be 0.291 year in average. Conclusion. Varenicline therapy of patients with angina pectoris is the economy before cardiac surgery , and after their execution, and this applies not only young, but older patients. The desirability of varenicline including to federal and regional programs to reduce cardiovascular morbidity and mortality is shown.

  6. Estudio de la motricidad global, motricidad ocular y lectura en Educación Primaria

    OpenAIRE

    Intxausti-Iturbe, Ane

    2014-01-01

    Este trabajo presenta un estudio realizado en Educación Primaria. En concreto, el propósito del presente trabajo es estudiar la motricidad global y ocular, la comprensión lectora y la velocidad lectora en un grupo de alumnos de segundo de Educación Primaria. Para ello, se aplicaron una serie de pruebas para evaluar las variables mencionadas. Los resultados evidencian que parte de la muestra presenta dificultades en las variables de motricidad global y ocular y en la comprensión y velocidad...

  7. Las computadoras en la educación primaria: Un estudio piloto

    OpenAIRE

    Jesús Francisco Galaz Fontes

    1989-01-01

    De un grupo de cuarto año de primaria se seleccionó a diez estudiantes para tomar un pequeño curso de Logo con una maestra, también de primaria, que había sido previamente entrenada en dicho lenguaje de computación. Ambos grupos de sujetos resolvieron un pretest y un postest de aritmética. Los datos muestran que el grupo que recibió el entrenamiento Logo tuvo una mejor ejecución en el postest que el grupo control. Además, las opiniones de los estudiantes, padres de familia y maestra fueron, e...

  8. Inteligencia emocional y responsabilidad social en Educación Primaria

    OpenAIRE

    Sancho Arranz, Verónica

    2014-01-01

    Inteligencia Emocional y Responsabilidad Social en Educación Primaria es un Trabajo de Fin de Máster teórico-experimental. Consiste en estudiar qué grado de relación e influencia tiene la Responsabilidad Social entre el alumnado del tercer ciclo de Educación Primaria para la mejora de la Inteligencia Emocional-Social, con el propósito de promover intervenciones didácticas en esa línea. Para la obtención de datos se aplicaron dos cuestionarios (EARSA-P y EQ-i YV) en alumnado de 5º y 6º curso d...

  9. Reforma de la educación primaria y secundaria: Estrategia sectorial (2000)

    OpenAIRE

    Banco Interamericano de Desarrollo (BID)

    2000-01-01

    La estrategia sobre educación primaria y secundaria (GN-2067-3) resume lo que se conoce acerca de cómo mejorar la educación primaria y secundaria en América Latina y el Caribe y presenta un conjunto de objetivos y estrategias para guiar al BID. Se definen las cinco áreas críticas de la reforma --hacer que los maestros sean socios en el proceso de reforma, brindar más y mejores libros de texto y materiales, apoyar en forma selectiva el uso de la tecnología en la educación, descentralizar la ad...

  10. Prototipos de mujer en algunos materiales educativos de enseñanza primaria: atavismos y horizontes

    OpenAIRE

    Ileana Schmidt Díaz de León

    2003-01-01

    Los materiales educativos han sido considerados por los investigadores medios de socialización, especialmente los libros de texto de educación primaria. Este trabajo analiza, desde una perspectiva de género, los papeles sociales y la estructura de poder de la sociedad mexicana enseñada a los niños mexicanos a través de materiales educativos. Éstos incluyen manuales para el maestro y libros de texto gratuitos de primero y segundo grados de educación primaria escritos en español ...

  11. Procedimiento para la gestión ambiental en la escuela primaria

    OpenAIRE

    Migdely Barbarita Ochoa-Ávila; Rafael M. Ávila-Avila; Josefina del Carmen Pupo-Pérez; Edith Guerra-Avila

    2011-01-01

    Abordó resultados alcanzados con la investigación doctoral "Modelo y procedimiento de gestión ambiental para la escuela primaria" desarrollada desde el año 2006 hasta el presente, mediante la aplicación del procedimiento para la gestión ambiental en una muestra de escuelas primarias del municipio de Holguín, lo que tributa a la calidad del medio ambiente no solo en escuelas sino en el medio ambiente local. El procedimiento consta de cinco etapas y veinte pasos, este introduce un elemento dina...

  12. Uso y desarrollo de pensamiento relacional por alumnos de tercero de Primaria

    OpenAIRE

    Molina, Marta; Castro, Encarnación

    2006-01-01

    En esta comunicación se describen las estrategias de pensamiento relacional empleadas por un grupo de alumnos de tercero de Primaria en la resolución y construcción de igualdades numéricas de suma y resta. Este trabajo forma parte de un experimento de diseño centrado en el estudio del desarrollo de pensamiento relacional por alumnos de tercero de Primaria en el contexto de la resolución de igualdades numéricas, compuestas por números naturales, y basadas en relaciones o propiedades aritmética...

  13. DIFERENCIAS CULTURALES EN DEBERES Y DERECHOS ENTRE LOS DOCENTES DE INFANTIL-PRIMARIA Y SECUNDARIA

    Directory of Open Access Journals (Sweden)

    Faustino Larrosa Martínez

    2012-01-01

    Full Text Available El trabajo analiza las diferencias culturales entre el profesorado de Infantil-Primaria y Secundaria a la luz de sus deberes y derechos. Han participado 394 docentes de toda España de educación Infantil, Primaria y Secundaria, elegidos al azar, contestando a un cuestionario enviado por correo postal a los centros seleccionados aleatoriamente. Se utiliza como instrumento el cuestionario "Deberes y derechos del profesorado en la comunidad educativa" y se confirma la hipótesis: existen diferencias culturales docentes significativas que nos permiten establecer distintas subculturas.

  14. Calidad de vida en pacientes con osteoporosis en atención primaria

    OpenAIRE

    Mercedes Sánchez Barba; Ma. PurificaciónVicente Galindo; Ana Martín Casado; Enrique Vicente Rivera; Jose Luis Vicente Villardón; Ma. Purificación Galindo-Villardón

    2011-01-01

    El objetivo de esta investigación fue evaluar la calidad de vida en pacientes clasificados como osteoporóticos en el Ámbito de la Atención primaria. Se llevó a cabo un diseño observacional transversal, los pacientes fueron reclutados de forma consecutiva en un Centro de Salud de Atención primaria de Salamanca (España). Se utilizó un cuestionario sociodemográfico, el EuroQol-5D, para evaluar calidad de vida relacionada con la salud y el QUALEFFO para evaluar calidad de vida en pacientes clasif...

  15. La multimorbilidad vista desde la perspectiva de los profesionales de atención primaria

    OpenAIRE

    Roberto Nuño-Solinís; Koldo Piñera Elorriaga; Carolina Rodríguez Pereira; Amaia García Martínez; Mikel Ayala Gabilondo

    2014-01-01

    Objetivo: Explorar la percepción de profesionales clínicos de atención primaria del País Vasco sobre la multimorbilidad y su influencia en la práctica clínica y en la organización de la prestación sanitaria. Diseño: Estudio cualitativo basado en entrevistas, taller de storytelling y cocreación. Emplazamiento: Comunidad autónoma del País Vasco. Atención primaria de Osakidetza. Participantes: Participaron 14 profesionales clínicos: 6 especialistas de medicina de familia, 3 especialista...

  16. La comunicación social en educación primaria

    OpenAIRE

    Feria Moreno, Antonio

    1993-01-01

    El tratamiento pedagógico de la comunicación social en la etapa de Educación Primaria (uso didáctico de los medios de comunicación social, estrategias de análisis crítico, producción escolar ...), dista mucho de ser una realidad en la práctica educativa de nuestros centros docentes. Este artículo invita a maestras y maestros de Primaria a superar barreras, a abandonar reticencias y, en definitiva, a buscar modelos didácticos donde la comunicación social tenga cabida. The pedagogic treatmen...

  17. Apendagitis epiploica primaria: Clínica y evolución de 73 casos

    OpenAIRE

    Graciela M Vázquez; Manzotti, Matías E; Graciana Alessandrini; Sofía Lemos; María Clara Perret; Hugo N. Catalano

    2014-01-01

    La apendagitis epiploica primaria es una enfermedad relativamente infrecuente dentro de los diagnósticos diferenciales del abdomen agudo. Describimos las características clínicas y evolución de una serie de 73 casos de apendagitis epiploica primaria. Se realizó una búsqueda de imágenes ecográficas y tomográficas con diagnóstico de apendagitis en el sistema de información hospitalario electrónico del Hospital Alemán entre abril del 2007 y julio del 2013 y posteriormente se revisaron sus histor...

  18. The prognostic significance of angina pectoris experienced during the first month following acute myocardial infarction

    DEFF Research Database (Denmark)

    Jespersen, C M

    1997-01-01

    pectoris experienced during the first month following discharge from AMI. METHODS: In all, 803 patients included in the placebo arm of the Danish Verapamil Infarction Trial II were followed up for 18 months in 20 coronary care units in Denmark. The patients were randomized to placebo and were still...... risk which, however, only reached borderline statistical significance (hazard 1.52; 95%-CL: 0.96, 2.40). When patients were subdivided according to both angina pectoris and heart failure, those with one or both of these risk markers had significantly increased mortality (p 0.03) and reinfarction (p 0...

  19. Chest pain after percutaneous coronary intervention in patients with stable angina

    Directory of Open Access Journals (Sweden)

    Chang CC

    2016-08-01

    Full Text Available Chao-Chien Chang,1–3 Yueh-Chung Chen,4,5 Eng-Thiam Ong,1 Wei-Cheng Chen,1 Chia-Hsiu Chang,1 Kuan-Jen Chen,1 Cheng-Wen Chiang1 1Division of Cardiology, Department of Internal Medicine, Cathay General Hospital, Taipei, Taiwan, ROC; 2Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan, ROC; 3Department of Pharmacology, Taipei Medical University, Taipei, Taiwan, ROC; 4Division of Cardiology, Department of Internal Medicine, Taipei City Hospital Ren-Ai branch, Taipai, Taiwan, ROC; 5Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, ROC Background: Percutaneous coronary intervention (PCI has been widely used to treat acute coronary syndrome but is only recommended as an additional treatment to medical therapy and risk modification in patients with refractory or progressing angina. The number of PCI in this patient population is still increasing. Post-PCI chest pain (PPCP is one of the common problems of PCI. Its presentation and causes in patients with stable angina are poorly understood.Patients and methods: This study retrospectively collected clinical information of 167 patients who had stable angina and underwent elective PCI, including 70 patients with PPCP 24 hours after procedure and 97 patients without PPCP. The incidence and predictors of PPCP were analyzed.Results: The incidence of PPCP was 41.9% (70/167. Compared with non-PPCP patients, PPCP patients had more abnormal post-PCI electrocardiogram (ECG changes (new Q-waves, ST-segment shifts, or T-waves inversion and serum cardiac troponin I (cTnI elevation, more PCI vessels, and stent placement (all P<0.05. More PPCP patients required repeat revascularization than non-PPCP patients after PCI (P=0.043. PPCP was correlated with abnormal post-PCI ECG changes (P<0.0001, cTnI elevation (P<0.0001, post-PCI serum level of cTnI (P<0.0001, number of stents placed (P=0.009, and pre-PCI cTnI level (P=0.049. The strongest predictors of

  20. Association between thyroid dysfunction and incidence of atrial fibrillation in patients with stable angina pectoris

    Institute of Scientific and Technical Information of China (English)

    徐予

    2014-01-01

    Objective To explore the correlation between incidence of atrial fibrillation(AF)and thyroid dysfunction.Methods Patients with stable angina pectoris with thyroid function test results hospitalized at Fuwai Hospital from2011 Jan to 2011 Dec were included in this analysis(n=2 541).General clinical data and related biochemical parameters were analyzed.We divided patients into 5subgroups according to TSH levels:<0.55 mI U/L(n=105),0.55-2.49 mI U/L(n=1 599),2.50-4.77

  1. Diagnostic Value of Spiral on Kidney Angina%螺旋CT对肾绞痛的诊断价值

    Institute of Scientific and Technical Information of China (English)

    杨泽年; 张婷

    2003-01-01

    Objective Study the three methods' diacrisis value:X ray sheet of kidney angina cause of urinary calculus,vein renal pelvis contrast and spiral CT. Method Look back on and study 50 clinical kidney angina patients who have taken X ray sheet,or vein renal pelvis contrast, or spiral CT treatment. Compare those three methods and find the calculus positive rate and the areas of calculus frequently happening. Result X ray sheet finds that the calculus positive rate is 58%. Vein renal pelvis contrast finds that the calculus positive rate is 74%. Spiral CT finds that the calculus positive rate is 96% .All the calculus leans to appearing at the hypo - segment of ureter. And the Same - side kidney gets dropsy of different degree.Conclusion Urinary calculus, especially ureter hypo - segment calculus is the main cause of kidney angina. And spiral CT scanning is the best way to find calculus.

  2. Reduction of recurrent ischemia with abciximab during continuous ECG-ischemia monitoring in patients with unstable angina refractory to standard treatment (CAPTURE)

    NARCIS (Netherlands)

    S. Meij (Simon); R. Melkert (Rein); T. Lenderink (Timo); M.L. Simoons (Maarten); A.P.J. Klootwijk (Peter)

    1998-01-01

    textabstractBACKGROUND: In the CAPTURE (c7E3 Fab Anti Platelet Therapy in Unstable REfractory angina) trial, 1265 patients with refractory unstable angina were treated with abciximab or placebo, in addition to standard treatment from 16 to 24 hours preceding coronary intervention t

  3. Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease

    DEFF Research Database (Denmark)

    Mygind, Naja Dam; Michelsen, Marie Mide; Pena, Adam;

    2016-01-01

    microvascular dysfunction and the association with symptoms, cardiovascular risk factors, psychosocial factors, and results from diagnostic stress testing. METHODS AND RESULTS: After screening 3568 women, 963 women with angina-like chest pain and a diagnostic coronary angiogram without significant coronary....... CONCLUSION: Impaired CFVR was detected in a substantial proportion, which suggests that coronary microvascular dysfunction plays a role in the development of angina pectoris. CFVR was associated with few cardiovascular risk factors, suggesting that CFVR is an independent parameter in the risk evaluation of...

  4. Management of stable angina: A commentary on the European Society of Cardiology guidelines.

    Science.gov (United States)

    Ambrosio, Giuseppe; Komajda, Michel; Mugelli, Alessandro; Lopez-Sendón, José; Tamargo, Juan; Camm, John

    2016-09-01

    In 2013 the European Society of Cardiology (ESC) released new guidelines on the management of stable coronary artery disease. These guidelines update and replace the previous ESC guidelines on the management of stable angina pectoris, issued in 2006. There are several new aspects in the 2013 ESC guidelines compared with the 2006 version. This opinion paper provides an in-depth interpretation of the ESC guidelines with regard to these issues, to help physicians in making evidence-based therapeutic choices in their routine clinical practice. The first new element is the definition of stable coronary artery disease itself, which has now broadened from a 'simple' symptom, angina pectoris, to a more complex disease that can even be asymptomatic. In the first-line setting, the major changes in the new guidelines are the upgrading of calcium channel blockers, the distinction between dihydropyridines and non-dihydropyridine calcium channel blockers, and the presence of important statements regarding the combination of calcium channel blockers with beta-blockers. In the second-line setting, the 2013 ESC guidelines recommend the addition of long-acting nitrates, ivabradine, nicorandil or ranolazine to first-line agents. Trimetazidine may also be considered. However, no clear distinction is made among different second-line drugs, despite different quality of evidence in favour of these agents. For example, the use of ranolazine is supported by strong and recent evidence, while data supporting the use of the traditional agents appear relatively scanty. PMID:27222385

  5. RE-EVALUATION OF THE MECHANISM AND TREATMENT OF ANGINA DECUBITUS

    Institute of Scientific and Technical Information of China (English)

    陈纪林; 陈在嘉; 徐义枢; 高润霖; 寇文蓉; 姚康宝; 于全俊; 陶寿琪

    1996-01-01

    30 patients with angina decubittus(AD) were studied during hospitalization. These patients were found to have severe coronary artery obstructive lesions and an increase of myocardial oxygen consumption (MOC) before the onset to AD, indicating that AD belongs to the category of effort angina. 18 patients were investigated by continuous hemodynamic mordtoring. Three patients had significant increase in pulmonary artery diastolic pressure (PADP) before the onset. In the other 15 patients, PADP increased slightly in J2 and remained unchanged in 3 cases before the onset. Left ventriculography showed ejection fraction (EF))45% in 25 of the 27 patients. These results indicate that left ventricular (LV) systolic dysfunction is not a major factor in the pathogenesis of AD. The patients with LVEDP>12 mmHg constituted 60% of 25 patients with EF)45%, suggesting that these patients had obvious LV diastolic dysfunction, which may he the major factor in the pathogenesis of AD. According to the results of our treatment, Beta blockers may be used as the major form of treatment in the patients with AD.

  6. Ranolazine: Drug overview and possible role in primary microvascular angina management.

    Science.gov (United States)

    Cattaneo, Mattia; Porretta, Alessandra Pia; Gallino, Augusto

    2015-02-15

    Ranolazine is a novel well-tolerated anti-ischemic drug, which selectively inhibits late sodium current and exerts metabolic properties without any hemodynamic effect. Ranolazine has been approved as a second-line medical treatment for symptomatic stable coronary artery disease. Primary microvascular angina (MVA) is suspected when angina symptoms occur in patients with demonstrated myocardial ischemia, absence of myocardial disease and normal coronary artery angiography. Recent clinical data suggest that MVA represents a complex entity, which has been increasingly recognized as a significant cause of morbidity. High variability and low response to traditional anti-anginal treatment characterize primary MVA. Despite the fact that clinical and preclinical evidence provides information regarding ranolazine usefulness in primary MVA management, only three recent small randomized trials have investigated this issue. By selecting peer-reviewed literature in Pubmed and Cochrane Library, this review provides an overview on ranolazine pharmacology and efficacy, focusing on recent evidence suggesting its usefulness in management of primary MVA. PMID:25555283

  7. Efectividad de un programa multicomponente para dejar de fumar aplicado en atención primaria

    Directory of Open Access Journals (Sweden)

    Fernando Alonso-Pérez

    2014-05-01

    Conclusiones: El tratamiento multicomponente aplicado fue altamente efectivo. Se sugiere la conveniencia de realizar un entrenamiento específico a los profesionales de la salud de cara a implantar este tipo de intervenciones en el ámbito de la atención primaria, como alternativa al consejo médico para aquellos fumadores que lo precisen.

  8. Las computadoras en la educación primaria: Un estudio piloto

    Directory of Open Access Journals (Sweden)

    Jesús Francisco Galaz Fontes

    1989-01-01

    Full Text Available De un grupo de cuarto año de primaria se seleccionó a diez estudiantes para tomar un pequeño curso de Logo con una maestra, también de primaria, que había sido previamente entrenada en dicho lenguaje de computación. Ambos grupos de sujetos resolvieron un pretest y un postest de aritmética. Los datos muestran que el grupo que recibió el entrenamiento Logo tuvo una mejor ejecución en el postest que el grupo control. Además, las opiniones de los estudiantes, padres de familia y maestra fueron, en general, positivas respecto a la experiencia de aprender a programar Logo, así como en relación al uso de las computadoras en la educación primaria. Se discute si el uso educativo de las computadoras en general. y del lenguaje Logo en particular, puede representar un medio para mejorar el desempeño académico a nivel primaria, sobre todo en zonas urbanas de la frontera norte de México, donde la cultura y las condiciones económicas hacen más viable esta alternativa educativa.

  9. La informatización de la atención primaria de salud

    Directory of Open Access Journals (Sweden)

    Rodolfo J. Stusser Beltranena

    2006-12-01

    Full Text Available La informatización de la atención primaria de salud se percibe como un problema que se soluciona creando redes computarizadas entre los consultorios y policlínicos. El artículo brinda una visión panorámica del estado en que se encuentra el arte de la informatización de la atención primaria y la medicina general integral, en el mundo y en Cuba. Para ello, se sintetiza el origen prehistórico de ese nivel de atención y de la especialidad, así como el desarrollo contemporáneo de la informática y sus aplicaciones médicas; se define igualmente la atención primaria y su informática; se resumen los sistemas de información, las aplicaciones informáticas y sus desafíos; y se ofrece una visión práctica de la historia clínica-electrónica: corazón de la informática de atención primaria de salud y medicina general integral. Se concluye que Cuba ha trabajado 20 años informatizando la dispensarización y estadísticas para la gerencia de servicios de este nivel de atención, pero que también podría trabajar con el enfoque centrado en la vida del paciente, que contribuiría a crear una clasificación integradora de la salud con la enfermedad, y a computarizar la información y la toma de decisiones clínicas en el consultorio del médico, y en el futuro hasta en el hogar del paciente, elevando directamente la calidad de la atención primaria de salud.

  10. Unstable angina

    Science.gov (United States)

    ... a close relative such as a sibling or parent had heart disease before age 55 in a man or before age 65 in a woman) High blood pressure High LDL cholesterol Low HDL cholesterol Male gender Sedentary lifestyle (not getting enough exercise) Obesity Older ...

  11. Angina - discharge

    Science.gov (United States)

    ... Avoid salty and fatty foods. Stay away from fast-food restaurants. Your doctor can refer you to a ... Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol . 2007 Aug ...

  12. Unstable Angina

    Science.gov (United States)

    ... Privacy Policy What's Your Risk? Heart Attack Risk Assessment Determine your risk of having a heart attack or dying from coronary heart disease and get a report to discuss with your healthcare provider. Determine your risk of having a heart ...

  13. Microvascular Angina

    Science.gov (United States)

    ... Privacy Policy What's Your Risk? Heart Attack Risk Assessment Determine your risk of having a heart attack or dying from coronary heart disease and get a report to discuss with your healthcare provider. Determine your risk of having a heart ...

  14. Stable angina

    Science.gov (United States)

    ... and prasugrel). Your provider may recommend a cardiac rehabilitation program to help improve your heart's fitness. SURGICAL ... and the American Association for Thoracic Surgery, Preventive ... Society for Cardiovascular Angiography and Interventions, ...

  15. Ludwig's angina

    Science.gov (United States)

    ... the emergency room or call your local emergency number (such as 911) right away. Call your health care provider if you have symptoms of this condition, or if symptoms do not get better after treatment. Prevention Visit the dentist for regular checkups. Treat symptoms of mouth or ...

  16. Angina - discharge

    Science.gov (United States)

    ... Avoid salty and fatty foods. Stay away from fast-food restaurants. Your doctor can refer you to a ... Controlling your high blood pressure Dietary fats explained Fast food tips Heart attack - discharge Heart attack - what to ...

  17. Outcomes after revascularisation with everolimus- and sirolimus-eluting stents in patients with acute coronary syndromes and stable angina pectoris

    DEFF Research Database (Denmark)

    Antonsen, Lisbeth; Thayssen, Per; Hansen, Henrik S; Maeng, Michael; Tilsted, Hans-Henrik; Bøtker, Hans E; Ravkilde, Jan; Madsen, Morten; Sørensen, Henrik T; Thuesen, Leif; Lassen, Jens F; Jensen, Lisette O

    2014-01-01

    Aims: The aim of this substudy of the SORT OUT IV trial was to compare clinical outcomes among patients with acute coronary syndromes (ACS) and stable angina pectoris (SAP) treated with everolimus-eluting stents (EES) or sirolimus-eluting stents (SES). Methods and results: We performed a post hoc...

  18. Infuences of Previous Angina Pectoris on Coronary Collateral Circulation and Left Ventricular Function in Patients with Acute Myocardial Infarction

    Institute of Scientific and Technical Information of China (English)

    罗初凡; 杜志民; 胡承恒; 梅卫义; 伍贵富; 李怡; 马虹

    2001-01-01

    Objective To investigate the influences of previous angina pectoris on coronary collateral circulation and left ventricular function in patients with acute myocardial infarction. Methods 307 patients with a first episode acute myocardial infarction underwent selective coronary angiography and left ventriculography. The relation of previous angina pectoris to coronary collateral circulation, peak creatine kinase and left ventricular function were analyzed.Results ① In the 307 patients, there were 192(62.5 % ) with previous angina [PA ( + ) group] and 115 (37.5 % ) without [PA ( - ) group]. ②The peak creatine kinase (CK) and CK- MB were significantly higher in PA (-) group than in PA (+) group ( P < 0.05 for both comparisons) . ③ Collateral circulation to infarct- related artery was more likely to be present in PA (+) group than in PA (-) group ( P < 0.05) . ④ The left ventricular ejection fraction was significantly increased, and the left ventricular wall motion Cortina score decreased, in PA ( + ) group than in PA ( - ) group ( P < 0.01 for both comparisons) .Conclusion In patients with acute myocardial infarction, previous angina pectoris may have beneficial effects on coronary collateral circulation and left ventricular unction.

  19. Cardiac troponin T and CK-MB mass release after visually successful percutaneous transluminal coronary angioplasty in stable angina pectoris

    DEFF Research Database (Denmark)

    Ravkilde, J; Nissen, H; Mickley, H;

    1994-01-01

    The incidence of cardiac troponin T (Tn-T) and creatine kinase (CK) isoenzyme MB mass release was studied in 23 patients with stable angina pectoris undergoing visually successful percutaneous transluminal coronary angioplasty (PTCA). Serial blood samples were drawn for measurement of serum Tn...

  20. Creatine kinase and creatine kinase subunit-B in coronary sinus blood in pacing-induced angina pectoris

    DEFF Research Database (Denmark)

    Bagger, J P; Ingerslev, J; Heinsvig, E M

    1982-01-01

    In nine out of 10 patients with angiographic documented coronary artery disease, pacing-induced angina pectoris provoked myocardial production of lactate, whereas no significant release of either creatine kinase or creatine kinase subunit-B to coronary sinus and peripheral venous blood could be...

  1. STIMULATION CHARACTERISTICS, COMPLICATIONS, AND EFFICACY OF SPINAL-CORD STIMULATION SYSTEMS IN PATIENTS WITH REFRACTORY ANGINA - A PROSPECTIVE FEASIBILITY STUDY

    NARCIS (Netherlands)

    DEJONGSTE, MJL; NAGELKERKE, D; HOOYSCHUUR, CM; JOURNEE, HL; MEYLER, PWJ; STAAL, MJ; DEJONGE, P; LIE, KI

    1994-01-01

    Objectives: In a prospective study with a 1-year follow-up we evaluated: (1) the feasibility of a method for the adjustment of spinal cord stimulator (SCS) parameters, (2) complications of SCS, and (3) efficacy of SCS. Methods: In patients receiving an SCS for severe angina unresponsive to standard

  2. Spinal cord stimulation in the treatment of refractory angina : systematic review and meta-analysis of randomised controlled trials

    NARCIS (Netherlands)

    Taylor, Rod S.; De Vries, Jessica; Buchser, Eric; DeJongste, Mike J. L.

    2009-01-01

    Background: The aim of this paper was undertake a systematic review and meta-analysis of the use of spinal cord stimulation ( SCS) in the management of refractory angina. Methods: We searched a number of electronic databases including Medline, Embase and Cochrane Library up to February 2008 to ident

  3. Myocardial rest iodine-123-β-methyl-iodophenyl-pentadecanoic acid scintigraphy compared with dipyridamole stress thallium-201 scintigraphy in unstable angina

    International Nuclear Information System (INIS)

    Twelve patients with stable angina and 12 patients with unstable angina underwent rest iodine-123-β-methyl-iodophenyl-pentadecanoic acid (BMIPP), dipyridamole stress thallium scintigraphy and delayed thallium scintigraphy. In stable angina, sensitivity for detecting ischemic segments was higher in dipyridamole thallium (74%) than rest BMIPP (48%) images (p<0.05), but there was no significant difference between the 2 images in unstable angina. In unstable angina, the incidence of segments with higher defect scores on BMIPP images than on delayed thallium images and the opposite pattern was 27 and 5 (p<0.01). In stable angina, there was no difference. The mean defect score on BMIPP (6.3±5.6) was higher than that on delayed thallium scintigraphy (2.9±2.7) and it was almost the same as on the initial dipyridamole stress test (6.5±5.2). In conclusion, BMIPP scintigraphy is safer and may be as useful in detecting myocardial ischemia in patients with unstable angina as thallium scintigraphy. (author)

  4. Comparison of percutaneous coronary intervention versus conservative treatment in unstable angina pectoris

    International Nuclear Information System (INIS)

    Objective: To evaluate the efficacies of percutaneous coronary intervention (PCI) and drug treatment in patients with unstable angina (UAP). Methods: 248 patients with UAP were divided into two groups: conservative group of 123 patients who received antiplatelet, anticoagulant and antianginal therapies only and invasive group of 125 patients who underwent additional PCI 4.4 days after admission. The occurrence of death, AMI, recurrent angina, readmission were assessed during the first hospitalization year. Results: There was no difference in the incidence of composite endpoint of death or AMI between the two groups during the hospitalization (0.8 % vs 1.6 %, P > 0.05 ), but hospitalization duration was shorter in the invasive group than in the conservative group (10.3 ± 5.6 days vs 14.6 ± 10.7 days, P < 0.01 ). In duration of one year, the incidence of AMI (2.4% vs 8.9%, P<0.03), death (1.6% vs 6.5%, P<0.05), composite endpoint of death or AMI (4.0 % vs 13.0 % P < 0.02), recurrent angina pectoris (26.4 % vs 48.7, P <0.001), CABG (1.6% vs 10.5%, P<0.01) and readmission (24.8% vs 45.5%, P<0.01) were also lower in the invasive group than in the conservative group. Survival rate free of composite death or AMI for 1 year was higher in the invasive group than in the conservative group(96.0 % vs 86.9 %, P < 0.02). There was a definite benefit of the invasive treatment in reducing the risk of composite endpoint of death or AMI in patients with chest pain at rest, troponin T positive and three vessel diseases. Old age, three vessel diseases, LAD disease, lower LVEF, ST-segment depression, diabetes and hypertension were the independent factors associated with composite of death or AMI. Conclusions: In patients with UAP, PCI associated with routine antiplatelet, anticoagulant and antiischemic treatment significantly decreases the incidence of adverse cardiac events and improves the survival rate in one year. Such beneficial effects can be more obvious for high-risk patients

  5. Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage.

    Science.gov (United States)

    Cleophas, Ton J.M.; Niemeyer, Menco G.; van Der Wall, Ernst E.

    1996-12-01

    BACKGROUND: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. METHODS: In a randomized, double-blind crossover study, 89 patients with stable angina pectoris were used to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Patients were randomized to either 60 mg 5-ISMN once daily (o.d.) for 2 weeks or 30 mg 5-ISMN o.d. for 1 week followed by 60 mg 5-ISMN o.d. for 1 week. A 2-week placebo wash-out ensued, after which the alternative treatment was given. We assessed the occurrence of angina pectoris and headache by diary cards while taking into account the numbers of isosorbide dinitrate sublingual puffs and paracetamole tables required. Data were assessed for carryover and time effects. RESULTS: The two dosage regimens were equally efficient for the relief of angina pectoris without development of tolerance. Thirty percent of the patients never experienced headache from the given dosages. The remainder showed a highly significant time-effect: The total numbers of headache attacks in the 1st period of active treatment were 2,380 vs 1,400 attacks is the 2nd period (p < 0.003), yet significantly fewer patients had headaches on low dosages than high ones (45 vs 57, p < 0.02). CONCLUSIONS: Starting on a low dosage was associated with reduced frequency and severity of headache and did not notably influence the beneficial effect of nitrates on angina pectoris. One in three patients never experienced headache from the given dosages. The overall number of headache attacks in the 1st period of active treatment was significantly higher than that of the 2nd period, irrespective of the dosages given. PMID:11862241

  6. Evaluation of the Add-On Effect of Chinese Patent Medicine for Patients with Stable or Unstable Angina: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Chen Mao

    2013-01-01

    Full Text Available Chinese herbal medicine (CHM has been widely used as an adjunct to western medicine in treating angina in China. We carried out this systematic review to evaluate the effectiveness of CHM on top of western medicine for angina. This meta-analysis included 46 randomized control trials with 4212 patients. For trials that included stable angina patients, the CHM group had significant lower incidence of total heart events (relative risk (RR=0.50, 95% confidence interval (CI 0.33–0.78, myocardial infarction (RR=0.32, 95% CI 0.14–0.72, heart failure (RR=0.37, 95% CI 0.15–0.91, and angina (RR=0.46, 95% CI 0.30–0.71 than that of control group. For trials that included unstable angina patients, CHM led to significantly lower occurrence of total heart events (RR=0.46, 95% CI 0.32–0.66, myocardial infarction (RR=0.37, 95% CI 0.26–0.54, and angina (RR=0.36, 95%CI 0.26–0.51. Likewise, for trials that included stable or unstable angina patients, the rates of myocardial infarction (RR=0.34, 95% CI 0.17–0.68 and angina (RR=0.46, 95% CI 0.30–0.70 in CHM group were significantly lower than that in control group. In conclusion, CHM is very likely to be able to improve the survival of angina patients who are already receiving western medicine.

  7. Evaluation of the Add-On Effect of Chinese Patent Medicine for Patients with Stable or Unstable Angina: A Systematic Review and Meta-Analysis

    OpenAIRE

    Chen Mao; Vincent C H Chung; Jin-Qiu Yuan; Yuan-Yuan Yu; Zu-Yao Yang; Xin-Yin Wu; Jin-Ling Tang

    2013-01-01

    Chinese herbal medicine (CHM) has been widely used as an adjunct to western medicine in treating angina in China. We carried out this systematic review to evaluate the effectiveness of CHM on top of western medicine for angina. This meta-analysis included 46 randomized control trials with 4212 patients. For trials that included stable angina patients, the CHM group had significant lower incidence of total heart events (relative risk (RR) = 0.50, 95% confidence interval (CI) 0.33–0.78), myocar...

  8. Psychophysical rehabilitation aspects of patient with coronary heart disease and Angina.

    Directory of Open Access Journals (Sweden)

    Mohammed Ali Khaleel.

    2012-03-01

    Full Text Available It is analyzed scientific and methodological literature, considered the views of scientists on the link of stress and cardiovascular diseases. It is determined causes of stress, with recommendations for combating stress and its prevention. A program of rehabilitation for patients with coronary artery disease after hospital discharge is shown. The experiment involved 88 patients of coronary heart disease and angina, II and III functional class at the age of 40-65 years. Participants were divided into two groups the main and control. The control group performed a program of physical rehabilitation, including breathing and physical exercises, in the program we have added to the main group autogenic exercises. At the end the experiment revealed that the health indicators of main group better than the control group in 23%.

  9. Endothelial Dysfunction and Blood Viscosity Inpatients with Unstable Angina in Different Periods of a Solar Activity

    Science.gov (United States)

    Parshina, S. S.; Tokaeva, L. K.; Dolgova, E. M.; Afanas'yeva, T. N.; Strelnikova, O. A.

    The origin of hemorheologic and endothelial defects in patients with unstable angina (comparing with healthy persons) is determined by a solar activity period: the blood viscosity increases in a period of high solar activity in the vessels of small, medium and macro diameters, a local decompensate dysfunction of small vessels endothelium had been fixed (microcirculation area). In the period of a low solar activity there is an increase of a blood viscosity in vessels of all diameters, generalized subcompensated endothelial dysfunction is developed (on the background of the III phase blood clotting activating). In the period of a high solar activity a higher blood viscosity had been fixed, comparing with the period of a low solar activity.

  10. Serum Adenosine deaminase activity and C-reactive protein levels in unstable angina

    Directory of Open Access Journals (Sweden)

    Rani Surekha

    2003-01-01

    Full Text Available In unstable angina (USA patients, immunological responses contributing to inflammation play a vital role in plaque rupture and thrombosis causing stroke. In the present study an attempt is made to estimate the levels of adenosine deaminase activity, an immunoenzyme marker and C-reactive protein, a marker of inflammation in USA patients. 45 patients presenting USA and 50 age and sex matched healthy controls were included in the study. Serum ADA activity was measured spectrophotometrically at 630nm and serum C-reactive protein was detected using Avitex CRP kit, which is a rapid latex agglutination test. The Mean ADA levels were 41.15 ± 11.04 in patients and 20.71±5.63 in controls and 66.6% of patients and none of the controls were positive to CRP. The present study observed the importance of ADA as a serum marker in addition to CRP for assessing the immune response in USA patients.

  11. INFLUENCE OF MILDRONATE ON EFFICIENCY OF ANTIANGINAL THERAPY IN PATIENTS WITH STABLE BURDEN ANGINA

    Directory of Open Access Journals (Sweden)

    N. P. Kutishenko

    2015-12-01

    Full Text Available Aim. To study influence of mildronate (M on treatment efficiency of patients with ischemic heart disease (IHD, receiving standard antianginal therapy (AATMaterials and methods. Double-blind, randomized, placebo-controlled study was carried out in parallel groups. All patients continued the earlier prescribed AAT without changes. After control period (10-14 days was over, randomization of patients either to the treatment group (M 500mg twice per day, or to the control group (placebo (Pl twice per day was made for 6 weeks therapy. Criterion of treatment efficiency: increase in duration of trial with burden on treadmill (TB, decrease in angina attack frequency (AA and reduction in nitroglycerin taking (NTT. TB was carried out at the beginning (TB-1, at the end of the control period (TB-2, and at the end of the treatment (TB-3.Results. TB-1 and TB-2 had good reproducibility, their duration didn’t differ. At the end of the treatment additionally with M, growth in duration of TB-3 (p=0,002 was registered, while there was no growth of TB duration with the Pl treatment (p=0,07. During the treatment decrease in AA number both with M (p=0,002, and with Pl (p=0,02 was noted. With M treatment decrease in NTT treatment (p=0.02 was observed, while NTT with Pl didn’t change (p=0,7. Number of side effects, registered with M and Pl, didn’t differ.Conclusion. Mildronate provides additional benefits for patients with IHD with stable burden angina, when they do not reach desired effect with the prescribed AAT.

  12. Alterations in left ventricular function during therapy of unstable angina pectoris: relationship to clinical outcome

    International Nuclear Information System (INIS)

    We studied 30 consecutive patients with unstable angina during pain-free intervals with gated blood pool scintigraphy. The initial study was performed within 18 hours of admission to the coronary care unit. A second study was performed near the time of hospital discharge, after stabilization with medical therapy. Three months thereafter patients were categorized according to their worst anginal status following hospital discharge. Fifteen patients were New York Heart Association functional class I or II (group A); 15 patients were in functional class III or IV (group B). Left ventricular ejection fraction was similar at the time of initial study (55.9 +/- 2.18% and 56.0 +/- 3.55% for groups A and B respectively). At the time of hospital discharge the ejection fraction had risen to 60.3 +/- 1.85% (p less than 0.01) in group A and in group B it had fallen to 48.1 +/- 3.4% (p less than 0.005). End-systolic volume index in group B rose from 37 ml/m2 +/- 6.1 to 43 +/- 6.2 ml/m2 (p less than 0.005) at the time of the follow-up study. There were no significant intergroup patients during the two scintigraphic examinations. Eleven group B patients subsequently underwent coronary artery bypass surgery. A significant increase in ejection fraction and a significant decrease in end-systolic volume index were noted when these patients were restudied an average of 3.2 months after surgery. This study suggests that changes in left ventricular function during the course of unstable angina pectoris are common and may be detected by serial gated blood pool scintigraphy

  13. Estratificando o risco na angina instável com a ecocardiografia sob estresse com dobutamina Stratifying the risk in unstable angina with dobutamine stress echocardiography

    Directory of Open Access Journals (Sweden)

    Brivaldo Markman Filho

    2006-09-01

    Full Text Available OBJETIVO: Avaliar a importância da ecocardiografia sob estresse pela dobutamina (EED na estratificação de risco de pacientes com angina instável (AI de baixo a moderado risco, quanto à capacidade de predizer os eventos clínicos combinados (morte de causa cardiovascular, infarto agudo do miocárdio (IAM, AI recorrente, necessidade de revascularização miocárdica no seguimento de 6 meses. MÉTODOS: Estudo prospectivo, multicêntrico. Os pacientes incluídos estavam internados, assintomáticos havia 24 horas e a medicação em uso não era suspensa para a realização do exame. O EED era realizado preferencialmente até 72 horas da chegada ao hospital. RESULTADOS: Foram avaliados 95 pacientes consecutivos. O EED foi positivo para isquemia em 40 pacientes (42,1% e em 55 (57,9%, foi negativo. Eventos ocorreram em 28 pacientes, 26 dos quais tinham o EED positivo para isquemia miocárdica. Os outros 67 pacientes não tiveram eventos; desses, 53 tinham o EED negativo. A sensibilidade, especificidade, acurácia, valor preditivo positivo e negativo do teste frente aos desfechos foram: 92,9%, 79,1%, 83,2%, 65% e 96,4%, respectivamente. Sobrevida livre de eventos após 6 meses para os pacientes com EED negativo foi de 96%, comparada com 35% nos que tiveram o EED positivo (pOBJECTIVE: To evaluate the role of dobutamine stress echocardiography (DSE in the risk stratification of low to moderate risk unstable angina (UA patients, to predict the combined clinical outcome of cardiovascular death, myocardial infarction (MI, recurrent UA and the need of revascularization procedures in a 6 month period. METHODS: Multicenter prospective study. Patients should be admitted to the hospital and asymptomatic in the last 24 hours. The exam was performed up to 72 hours from the hospital admission and no medication was stopped prior to the test. RESULTS: Ninety-five consecutive patients were evaluated by DSE. Forty patients (42,1% had a positive ischemic test and

  14. Factors Associated with the Types of Heparin used in the Treatment of Unstable Angina at a Brazilian Hospital

    Directory of Open Access Journals (Sweden)

    Maria Auxiliadora Parreiras Martins

    2010-06-01

    Full Text Available

    Unfractionated heparin (UFH and low-molecularweight heparins (LMWHs are widely used in curative and preventive treatments of thromboembolic disorders. The aim of the study was to investigate factors associated with the choice of these types of heparin to treat patients with unstable angina under real conditions of hospital use. A cross-sectional study was performed in a private general hospital in Belo Horizonte, Brazil, from January 1st to December 31th, 2001. Data were collected from the hospital electronic database. Inpatients with angina who received enoxaparin or UFH were included in the survey. Data for 555 patients were recorded, including 401 treated with enoxaparin and 154 with UFH. Univariate analysis showed that male and elderly people predominated in both groups, with no statistical difference in the proportions (p>0.05. Multivariate analysis showed 4 factors associated with the use of enoxaparin: cardiac revascularization surgery (OR=0.434, arrhythmias (OR=9.343, risk factors for coronary artery disease (OR=1.333 and private health insurance (OR=0.297. Thus, clinical and organizational factors were associated with the type of heparin used by patients with unstable angina at this hospital. Further drug utilization studies are necessary to expand and improve the data available on the use of heparins in the hospital setting. Keywords: Hospital pharmacy/assessment. Angina pectoris/treatment. Heparin/prescription. Enoxaparin/prescription. RESUMO Fatores associados com os tipos de heparina usados no tratamento da angina instável em um hospital brasileiro A heparina não-fracionada (HNF e heparinas de baixo peso molecular (HBPM são amplamente utilizadas em tratamentos curativos e preventivos de tromboembolismo. O objetivo do estudo foi investigar os fatores associados com a escolha desses tipos de heparinas para tratar pacientes com angina instável sob as condições reais de uso hospitalar. Trata-se de um estudo

  15. La comunicación oral en el aula de Educación Primaria

    OpenAIRE

    Jiménez Rosón, Francisco

    2013-01-01

    En el presente Trabajo Fin de Grado se trata la comunicación oral en las aulas de Primaria. En él se presenta una propuesta de intervención didáctica con el fin de mejorar la competencia comunicativa oral en el alumnado del tercer ciclo de Educación Primaria ante las carencias visibles hoy en día en el uso de la lengua oral. La metodología que se piensa llevar a cabo toma a los alumnos como centro del aprendizaje y realizando una enseñanza a través de la práctica. La propuesta de interven...

  16. Impact of Clinical Presentation (Stable Angina Pectoris vs Unstable Angina Pectoris or Non-ST-Elevation Myocardial Infarction vs ST-Elevation Myocardial Infarction) on Long-Term Outcomes in Women Undergoing Percutaneous Coronary Intervention With Drug-Eluting Stents

    DEFF Research Database (Denmark)

    Giustino, Gennaro; Baber, Usman; Stefanini, Giulio Giuseppe; Aquino, Melissa; Stone, Gregg W; Sartori, Samantha; Steg, Philippe Gabriel; Wijns, William; Smits, Pieter C; Jeger, Raban V; Leon, Martin B; Windecker, Stephan; Serruys, Patrick W; Morice, Marie-Claude; Camenzind, Edoardo; Weisz, Giora; Kandzari, David; Dangas, George D; Mastoris, Ioannis; Von Birgelen, Clemens; Galatius, Soren; Kimura, Takeshi; Mikhail, Ghada; Itchhaporia, Dipti; Mehta, Laxmi; Ortega, Rebecca; Kim, Hyo-Soo; Valgimigli, Marco; Kastrati, Adnan; Chieffo, Alaide; Mehran, Roxana

    2015-01-01

    The long-term risk associated with different coronary artery disease (CAD) presentations in women undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) is poorly characterized. We pooled patient-level data for women enrolled in 26 randomized clinical trials. Of 11......,577 women included in the pooled database, 10,133 with known clinical presentation received a DES. Of them, 5,760 (57%) had stable angina pectoris (SAP), 3,594 (35%) had unstable angina pectoris (UAP) or non-ST-segment-elevation myocardial infarction (NSTEMI), and 779 (8%) had ST...... presentations. After multivariable adjustment, STEMI was independently associated with greater risk of 3-year mortality (hazard ratio [HR] 3.45; 95% confidence interval [CI] 1.99 to 5.98; p <0.01), whereas no differences were observed between UAP or NSTEMI and SAP (HR 0.99; 95% CI 0.73 to 1.34; p = 0.94). In...

  17. Servicios farmacéuticos en la atención primaria en salud

    OpenAIRE

    Rafael Mota PINHEIRO

    2010-01-01

    Este artigo aborda las bases políticas y conceptuales de la atención farmacéutica en el Brasil, a partir de las definiciones básicas de los términos relacionados con el cuidado a la salud. Enfoca la relación y el papel de la atención farmacéutica con la atención primaria, y los principales retos e factores críticos.

  18. Symptoms of angina pectoris increase the probability of disability pension and premature exit from the workforce even in the absence of obstructive coronary artery disease

    DEFF Research Database (Denmark)

    Jespersen, Lasse; Abildstrøm, Steen Z; Hvelplund, Anders;

    2013-01-01

    To evaluate probabilities of disability pension (DP) and premature exit from the workforce (PEW) in patients with stable angina symptoms and no obstructive coronary artery disease (CAD) at angiography compared with obstructive CAD and asymptomatic reference individuals.......To evaluate probabilities of disability pension (DP) and premature exit from the workforce (PEW) in patients with stable angina symptoms and no obstructive coronary artery disease (CAD) at angiography compared with obstructive CAD and asymptomatic reference individuals....

  19. Effect of Atorvastatin and Pioglitazone on Plasma Levels of Adhesion Molecules in Non-Diabetic Patients With Hypertension or Stable Angina or Both

    OpenAIRE

    Pattan, Vishwanath; Seth, Sandeep; Jehangir, Waqas; Bhargava, Balram; Maulik, Subir Kumar

    2015-01-01

    Background It was to study the effect of atorvastatin, pioglitazone and their combination on plasma levels of adhesion molecules in patients with hypertension or stable angina or both. Methods It was an open-label, randomized parallel-group study. Forty-five atorvastatin-naive patients with hypertension or stable angina or both, were randomized to receive either atorvastatin (19 patients; 10 mg OD for 12 weeks) or pioglitazone (26 patients; 30 mg OD for 12 weeks). Another group of 30 patients...

  20. Resolution of Angina Pectoris and Improvement of the Coronary Flow Reserve after Ranolazine Treatment in a Woman with Isolated Impaired Coronary Microcirculation

    OpenAIRE

    Alessandro Santoro; Vincenzo Schiano Lomoriello; Ciro Santoro; Riccardo Muscariello; Maurizio Galderisi

    2013-01-01

    In a 61-year-old woman with well controlled arterial hypertension, hypercholesterolemia, and smoke and suffering from recurrent angina pectoris despite angiographically normal epicardial coronary vessels and maximal therapy, the replacement of nitrates with novel antiangina drug ranolazine, after 6-month therapy, induced a complete relief of angina and a relevant rising of the transthoracic Doppler-derived coronary flow reserve (CFR). The present clinical case underlines therefore how in pati...

  1. Long-Term Preservation of Left Ventricular Systolic Function in Patients With Refractory Angina Pectoris and Inducible Myocardial Ischemia on Optimal Medical Therapy.

    Science.gov (United States)

    Slavich, Massimo; Maranta, Francesco; Fumero, Andrea; Godino, Cosmo; Giannini, Francesco; Oppizzi, Michele; Colombo, Antonio; Fragasso, Gabriele; Margonato, Alberto

    2016-05-15

    Refractory angina pectoris (RAP) represents a clinical condition characterized by frequent episodes of chest pain despite therapy optimization. According to myocardial stunning and myocardial hibernation definitions, RAP should represent the ideal condition for systolic dysfunction development. We aim to investigate the evolution of left ventricular (LV) function in patients with RAP. A retrospective study which encompasses 144 patients with RAP referred to our institution from 1999 to December 2014 was performed. Of them, 88 met the inclusion criteria, and LV function was assessed by echocardiography. All of them had persistent angina episodes on top of optimal medical therapy and evidence of significant inducible myocardial ischemia and no further revascularization options. Nitrates consumption rate, time of angina duration, and the number of angina attacks were evaluated. In the whole population, ejection fraction (EF) was 44% ± 2. EF was significantly lower in patients with previous myocardial infarction (41% ± 1.5 vs 51% ± 1.8, p 5 years (5 years 44% ± 2 [n = 44]; p 0.02). Long-term LV function in patients with RAP is generally preserved. A previous history of myocardial infarction is the only determinant in the development of systolic dysfunction. In conclusion, frequent angina attacks and a long-term history of angina are not apparently associated to worse LV function. PMID:27055755

  2. Innovative Strategy in Treating Angina Pectoris with Chinese Patent Medicines by Promoting Blood Circulation and Removing Blood Stasis: Experience from Combination Therapy in Chinese Medicine.

    Science.gov (United States)

    Xiong, Xing-Jiang; Wang, Zhong; Wang, Jie

    2015-01-01

    Coronary heart disease (CHD) is one of the leading causes of death worldwide. Moreover, angina pectoris is one of the most important types of CHD. Therefore, prevention and effective treatment of angina pectoris is of utmost importance in both China and western countries. However, undesirable effects of antianginal therapy do influence treatment adherence to a certain extent. Therefore, it's not surprising that, complementary and alternative medicine (CAM), including Chinese medicine (CM), are widely welcomed among patients with CHD, hoping that it might complement western medicine. In our previous studies, blood stasis syndrome (BSS) (Xueyu Zheng) was the main syndrome (Zheng-hou) of angina pectoris. Currently, China Food and Drug Administration authoritatively recommended more than 200 Chinese patent medicines (CPMs) as complementary or adjunctive therapies for symptom management and enhancing quality of life along with mainstream care on angina pectoris management in mainland China. This paper reviewed 4 kinds of most frequently-used CPMs by promoting blood circulation and removing blood stasis in the treatment of angina pectoris. It aims to evaluate the current evidence of CPMs in combination therapy for angina pectoris. This review indicated that CPMs as adjunctive treatment to routine antianginal therapy play an active role in reducing the incidence of primary endpoint events, decreasing anginal attack rate, and improving electrocardiogram. Additionally, CPMs have been proven relatively safe. Further rigorously designed clinical trials should be conducted to confirm the results. PMID:25360837

  3. Stable angina pectoris with no obstructive coronary artery disease is associated with increased risks of major adverse cardiovascular events

    DEFF Research Database (Denmark)

    Jespersen, Lasse; Hvelplund, Anders; Abildstrøm, Steen Z;

    2012-01-01

    (MACE), defined as cardiovascular death, myocardial infarction, stroke or heart failure, and all-cause mortality. Significantly more women (65%) than men (32%) had no obstructive CAD (P<0.001). In Cox's models adjusted for age, body mass index, diabetes, smoking, and use of lipid-lowering or...... stable angina and normal coronary arteries or diffuse non-obstructive CAD have elevated risks of MACE and all-cause mortality compared with a reference population without ischaemic heart disease.......AimsPatients with chest pain and no obstructive coronary artery disease (CAD) are considered at low risk for cardiovascular events but evidence supporting this is scarce. We investigated the prognostic implications of stable angina pectoris in relation to the presence and degree of CAD with no...

  4. Predictors of coronary intervention-related myocardial infarction in stable angina patients pre-treated with statins

    OpenAIRE

    Veselka, Josef; Hájek, Petr; Malý, Martin; Zemánek, David; Adlová, Radka; Tomašov, Pavol; Martinkovičová, Lucie; Tesař, David; Červinka, Pavel

    2011-01-01

    Introduction Peri-procedural myocardial infarction (PMI) is a frequent and prognostically important complication of percutaneous coronary intervention (PCI). This study was designed to determine the predictors of PMI in patients pre-treated with statins. Material and methods A total of 418 stable angina pectoris patients taking statins and aspirin were included. All the patients underwent PCI. Serum concentrations of creatine kinase (CK-MB mass) and troponin I (TnI) were measured prior to and...

  5. Richtlinien zur Diagnostik und Therapie der instabilen Angina pectoris und des Non-Q-Wave-Myokardinfarktes: vorgeschlagene Revisionen

    OpenAIRE

    Huber K; Gaul G; Glogar HD; Kaliman J; Mlczoch J

    2000-01-01

    Die letzten Praxis-Empfehlungen der United States Agency for Health Care Policy and Research zum Thema "Diagnose und Behandlung der instabilen Angina Pectoris (IAP)" stammen aus dem Jahre 1994 und wurden trotz der rasanten Fortschritte auf diesem Gebiet in den vergangenen 5 Jahren nicht erneuert. Das International Cardiology Forum (ICF) hat Ende 1998 die existierenden Richtlinien diskutiert und Vorschläge gemacht, in welchen Bereichen die Diagnostik und die Therapie der IAP aufgrund der mittl...

  6. Factors Associated with the Types of Heparin used in the Treatment of Unstable Angina at a Brazilian Hospital

    OpenAIRE

    Maria Auxiliadora Parreiras Martins; Sérgia Maria Starling de Magalhães; Cibele Comini César; Adriano Max Moreira Reis; Mauro Henrique Nogueira Guimarães de Abreu

    2010-01-01

    Unfractionated heparin (UFH) and low-molecularweight heparins (LMWHs) are widely used in curative and preventive treatments of thromboembolic disorders. The aim of the study was to investigate factors associated with the choice of these types of heparin to treat patients with unstable angina under real conditions of hospital use. A cross-sectional study was performed in a private general hospital in Belo Horizonte, Brazil, from January 1st to December 31th, 2001. Data...

  7. Periodontal disease in relation to selected parameters of the cardiovascular system in a group of patients with stable angina pectoris

    OpenAIRE

    Włosowicz, Monika; Wożakowska-Kapłon, Beata; Górska, Renata

    2014-01-01

    Introduction Periodontal diseases (PD), which are the cause of chronic inflammatory processes, can develop increased susceptibility to vascular diseases through atherosclerosis. Due to the raised inflammatory and thrombotic risk, PD can have a significant influence on the course and results of stable angina pectoris (SAP). Objectives The aim of the study is to evaluate the influence of chosen PD parameters on selected cardiovascular system parameters, and the correlation between chosen parame...

  8. Can C reactive protein or troponins T and I predict outcome in patients with intractable unstable angina?

    OpenAIRE

    Curzen, N; Patel, D; Kemp, M; Hooper, J.; Knight, C.; Clarke, D.; Wright, C; Fox, K.

    1998-01-01

    Objective—To determine whether a single blood test for the measurement of C reactive protein, or troponin I or T concentrations could be used to stratify patients with intractable unstable angina awaiting transfer for coronary angiography by correlating these values with coronary anatomy and transient myocardial ischaemia.
Design—Prospective study.
Setting—Tertiary cardiac unit.
Patients—All patients admitted to their local hospital with ischaemic chest pain, uncontrolled by medical treatment...

  9. The Relationship Between Ankle-Brachial Index and Number of Involved Coronaries in Patients with Stable Angina

    OpenAIRE

    Sadeghi, Masoumeh; Tavasoli, Aliakbar; Roohafza, Hamidreza; Sarrafzadegan, Nizal

    2010-01-01

    BACKGROUND Atherosclerosis is the commonest cause of vascular disease which can involve peripheral and/or cardiac vessels. This study was conducted to evaluate the possible link between Ankle-Brachial Index (ABI) and coronary vessel involvement in patients with stable angina. METHODS This cross-sectional study was conducted in 2008 on 120 individuals who were hospitalized in Chamran Heart Center and underwent coronary angiography. A questionnaire was completed to obtain demographic informatio...

  10. A controlled comparison of oxyfedrine, isosorbide dinitrate and placebo in the treatment of patients suffering attacks of angina pectoris.

    OpenAIRE

    Whittington, J; Raftery, E B

    1980-01-01

    1 In a group of 23 patients with documented ischaemic heart disease who experienced angina pectoris, oral oxyfedrine (24 mg three times daily) was compared with isosorbide dinitrate (10 mg three times daily) and placebo in a double-blind double-crossover clinical trial. 2 Isosorbide dinitrate appeared no better than placebo, either in terms of symptomatic relief or ECG responses to exercise. Thirty eight per cent of patients complained of headaches and 28% had to cease taking the drug for thi...

  11. Drug efficacy in treating stable angina pectoris: a protocol for network meta-analysis of randomised controlled trials

    OpenAIRE

    Jia, Yongliang; Leung, Siu-wai

    2014-01-01

    Introduction There were 11 pairwise meta-analysis on the efficacy of β-blockers (including atenolol, propranolol, bisoprolol, metoprolol and nadolol), calcium channel blockers (including amlodipine, diltiazem, felodipine, nifedipine and verapamil), and nitrates (including isosorbide dinitrate, isosorbide mononitrate and nitroglycerin) in treating stable angina pectoris. No network meta-analytic study has been published to evaluate the efficacies of these antianginal drugs. Current clinical gu...

  12. Association of low levels of vitamin D with chronic stable angina: A prospective case-control study

    Directory of Open Access Journals (Sweden)

    Ab Hameed Raina

    2016-01-01

    Full Text Available Background: Coronary artery disease (CAD is a major cause of death and disability in developed countries. Chronic stable angina is the initial manifestation of CAD in approximately 50% of the patients. Recent evidence suggests that vitamin D is crucial for cardiovascular health. The prevalence of vitamin D deficiency in our region is 83%. A low level of vitamin D is associated with chronic stable angina. Aim: This study was aimed at supporting or refuting this hypothesis in our population. Materials and Methods: The study was a prospective case-control study. We studied 100 cases of chronic stable angina and compared them with 100 matched controls. Vitamin D deficiency was defined as <20 ng/mL, vitamin D insufficiency as 20-30 ng/mL and normal vitamin D level as 31-150 ng/mL. Results: The prevalence of vitamin D deficiency among cases and controls was 75% and 10%, respectively. 75% of the cases were vitamin D-deficient (<20 ng/mL; 12% were vitamin D-insufficient (20-30 ng/mL, and 13% had normal vitamin D levels (31-150 ng/mL. None had a toxic level of vitamin D. Among the controls, 10% were vitamin D-deficient, 33% were vitamin D-insufficient, and 57% had normal vitamin D levels. The mean vitamin level among cases and controls was 15.53 ng/mL and 40.95 ng/mL, respectively, with the difference being statistically significant (P ≤ 0.0001. There was no statistically significant relation between the disease severities, i.e., on coronary angiography (CAG with vitamin D level. Among the cases, we found that an increasing age was inversely related to vitamin D levels (P = 0.027. Conclusion: Our study indicates a correlation between vitamin D deficiency and chronic stable angina. Low levels may be an independent, potentially modifiable cardiovascular risk factor.

  13. Evidence of a cellular protective effect by antecedent angina independent of collateral flow recruitment during coronary angioplasty in humans

    International Nuclear Information System (INIS)

    The main aim of this study was to elucidate whether the beneficial effect of antecedent angina is a cellular protective effect or the result of an increase of collateral flow. Of 42 patients with angina who underwent percutaneous transluminal coronary angioplasty (PTCA) for proximal left anterior descending artery (LAD) stenosis, 22 had experienced antecedent anginal pain (AP) within 7 days prior to PTCA. 99mTc-sestamibi was injected during balloon inflation, and quantitative analysis of ischemic severity during coronary occlusion was calculated (SS). An electrocardiogram was recorded during ballooning to calculate the sum of ST elevation (ΣST). ΣST was significantly reduced in patients with AP compared with patients without AP (1.88±0.89 mV vs 1.18±0.74 mV, p=0.0088); however, no difference was observed in defect severity. A close correlation was observed between SS and ΣST in both groups. The multivariate regression model demonstrated that both a large SS (p<0.0001) and the absence of preceding AP (p=0.001) were significantly related to the elevation of ΣST. Recent angina can render the myocardium more resistant to subsequent ischemia during angioplasty and is true preconditioning rather than simply an increase of flow. (author)

  14. Use of Health Care System-Supplied Aspirin by Veterans With Postoperative Heart Attack or Unstable Angina.

    Science.gov (United States)

    Rivera, Cathleen M; Copeland, Laurel A; McNeal, Catherine J; Mortensen, Eric M; Pugh, Mary J; MacCarthy, Daniel J

    2015-10-01

    Evidence-based guidelines for the use of aspirin in secondary prevention of cardiovascular disease events are well established. Despite this, the prevalence of aspirin use for secondary prevention is suboptimal. The study aimed to determine the prevalence of aspirin use for secondary prevention of cardiovascular disease events when it is dispensed as a prescription, as is performed in the Veterans Affairs (VA) managed care system. VA patients who had undergone major surgery and experienced a postoperative myocardial infarction (MI) or unstable angina between the years 2005 and 2009 were identified from administrative databases. VA pharmacy records were used to determine whether a prescription for aspirin was filled after the postoperative MI or unstable angina. Multivariable logistic regression models estimated odd ratios of filling aspirin prescriptions for the predictors of interest. Of the 321,131 men and women veterans who underwent major surgery, 7,700 experienced a postoperative MI or unstable angina. Among those 7,700, 47% filled an aspirin prescription. Only 59% of veterans with no co-pay filled an aspirin prescription. Aspirin fills were more common in younger veterans, Blacks, Hispanics, males, hypertensive veterans, mentally ill patients, those with no co-pay and those prescribed antiplatelets/anticoagulants in addition to aspirin postoperatively. These findings suggest that the impact of dispensing aspirin as a prescription may not be significant in increasing the appropriate use of aspirin for secondary prevention. PMID:26351774

  15. Pacing-induced ST segment deviation in patients with unstable angina: clinical, angiographic, and hemodynamic correlation.

    Science.gov (United States)

    Hussain, K M; Gould, L; Pomerantsev, E V; Angirekula, M; Bharathan, T

    1995-07-01

    To assess the clinical, coronary arteriographic, and hemodynamic differences between the unstable angina patients manifesting ST segment depression and those showing ST segment elevation as well as those demonstrating chest pain only without ST segment deviation during pacing, low-dose digital subtraction ventriculography was performed in 33 patients before and after abrupt cessation of atrial pacing during selective coronary arteriography. Transient ST segment depression during pacing was observed in 17 patients (52%), whereas 6 patients (18%) showed ST segment elevation; however, 10 patients (30%) did not manifest any ST segment deviation in spite of typical chest pain. Hypertension and a history of myocardial infarction were observed in a significantly higher (P < 0.05) proportion of patients with ST segment depression than in those with ST elevation. Patients who manifested ST segment depression during pacing had a higher incidence of triple-vessel disease (65 vs 17%; P < .05) as compared with the patients with ST segment elevation. Indirect evidence of intracoronary thrombi (complicated lesion, abrupt occlusion, and intraluminal filling defect) was noticed in a higher frequency (P < 0.05) in the group of patients with ST elevation during pacing. In patients with ST segment depression, no significant changes of global left ventricular (LV) functional parameters were observed. However, the length of the LV severe hypokinetic region was increased significantly (6.2 +/- 3.1 vs 23.5 +/- 6.2%; P < 0.005) during pacing in this group of patients. The shortening of the affected segments of the left ventricle was decreased significantly (52.3 +/- 3.6 vs 38.3 +/- 4.9%; P < 0.05) in these patients during pacing. In the group of patients with ST segment elevation during pacing, decrease in ejection fraction was associated with significant (P < 0.01) increase in midwall equatorial diastolic stress as compared with the patients with pacing-induced ST segment depression as

  16. The prevalence of angina symptoms and association with cardiovascular risk factors, among rural, urban and rural to urban migrant populations in Peru

    Directory of Open Access Journals (Sweden)

    Gilman Robert H

    2010-10-01

    Full Text Available Abstract Background Rural-to-urban migration in low- and middle-income countries causes an increase in individual cardiovascular risk. Cost-effective interventions at early stages of the natural history of coronary disease such as angina may stem an epidemic of premature coronary deaths in these countries. However, there are few data on the prevalence of angina in developing countries, whilst the understanding the aetiology of angina is complicated by the difficulty in measuring it across differing populations. Methods The PERU MIGRANT study was designed to investigate differences between rural-to-urban migrant and non-migrant groups in specific cardiovascular disease risk factors. Mass-migration seen in Peru from 1980s onwards was largely driven by politically motivated violence resulting in less 'healthy migrant' selection bias. The Rose angina questionnaire was used to record chest pain, which was classified definite, possible and non-exertional. Mental health was measured using the General Health Questionnaire (GHQ-12. Mantel-Haenszel odds ratios (adjusted for age, sex, cardiovascular disease risk factors and mental health were used to assess the risk of chest pain in the migrant and urban groups compared to the rural group, and further to assess the relationship (age and sex-adjusted between risk factors, mental health and chest pain. Results Compared to the urban group, rural dwellers had a greatly increased likelihood of possible/definite angina (multi-adjusted OR 2.82 (1.68- 4.73. Urban and migrant groups had higher levels of risk factors (e.g. smoking - 20.1% urban, 5.5% rural. No diabetes was seen in the rural dwellers who complained of possible/definite angina. Rural dwellers had a higher prevalence of mood disorder and the presence of a mood disorder was associated with possible/definite angina in all three groups, but not consistently with non-exertional chest pain. Conclusion Rural groups had a higher prevalence of angina as

  17. Typische Angina pectoris-Symptomatik bei normalem Koronarangiogramm: Gibt es geschlechtsspezifische Unterschiede?

    Directory of Open Access Journals (Sweden)

    Graf S

    2008-01-01

    Full Text Available 10–30 % aller Patientinnen und Patienten mit typischer Angina pectoris-Symptomatik und positivem Belastungstest weisen angiographisch unauffällige epikardiale Koronarien auf. Diese Befundkonstellation wird auch als Syndrom X bezeichnet. In der folgenden Übersicht soll auf geschlechtsspezifische Unterschiede sowie mögliche Ursachen dieses Krankheitsbildes eingegangen werden. So konnte gezeigt werden, dass die diagnostische Wertigkeit nicht-invasiver Tests wie Ergometrie und Myokardszintigraphie bei Frauen und Männern unterschiedlich ist und ein "falsch positiver" Test durch geschlechtsspezifische methodische Probleme hervorgerufen sein kann. Ein weiterer Grund für falsch positive Ergebnisse nicht-invasiver Tests kann das Vorliegen einer mikrovaskulären koronaren Herzkrankheit darstellen. Auf die Häufigkeit und Geschlechtsverteilung dieser Erkrankung und deren Prognose sowie mögliche Therapieansätze wird in der folgenden Übersicht eingegangen. Des Weiteren wird auf mögliche ursächliche Zusammenhänge, im Besonderen mit der Bedeutung des Risikofaktorenprofils, hingewiesen.

  18. Der Einsatz von niedermolekularen Heparinen bei instabiler Angina pectoris und nicht-transmuralem Myokardinfarkt

    Directory of Open Access Journals (Sweden)

    Huber K

    1999-01-01

    Full Text Available Im vorliegenden Artikel wird die Anwendung unterschiedlicher niedermolekularer Heparine bei instabiler Angina und nicht-transmuralem Infarkt auf dem neuesten Stand der internationalen Datenlage besprochen. Dabei scheint Enoxaparin die höchste Effektivität unter den getesteten LMW-Heparinen in der Akutphase der Erkrankung zu besitzen, da zwei durchgeführte Studien (ESSENCE, TIMI-11B signifikante Vorteile gegenüber Standard-Heparin nachgewiesen haben. Demgegenüber scheint Dalteparin Vorteile in der längerdauernden Anwendung nach der Akutphase zu haben (FRISC-II. Da die Patientenpopulationen in den bisher durchgeführten Studien aber nicht sicher vergleichbar sind, da zu wenig Daten über die mögliche klinische Bedeutung pharmakologischer Unterschiede der verschiedenen LMW-Heparine vorliegen, und vor allem, weil es keine prospektiven, randomisierten Vergleichsstudien zwischen verschiedenen LMW-Heparinen gibt, kann derzeit nicht, durch wissenschaftliche Daten abgesichert, einem der untersuchten LMW-Heparine der Vorteil gegenüber einem anderen in dieser Indikation gegeben werden.

  19. Optimizing prescription of chinese herbal medicine for unstable angina based on partially observable markov decision process.

    Science.gov (United States)

    Feng, Yan; Qiu, Yu; Zhou, Xuezhong; Wang, Yixin; Xu, Hao; Liu, Baoyan

    2013-01-01

    Objective. Initial optimized prescription of Chinese herb medicine for unstable angina (UA). Methods. Based on partially observable Markov decision process model (POMDP), we choose hospitalized patients of 3 syndrome elements, such as qi deficiency, blood stasis, and turbid phlegm for the data mining, analysis, and objective evaluation of the diagnosis and treatment of UA at a deep level in order to optimize the prescription of Chinese herb medicine for UA. Results. The recommended treatment options of UA for qi deficiency, blood stasis, and phlegm syndrome patients were as follows: Milkvetch Root + Tangshen + Indian Bread + Largehead Atractylodes Rhizome (ADR = 0.96630); Danshen Root + Chinese Angelica + Safflower + Red Peony Root + Szechwan Lovage Rhizome Orange Fruit (ADR = 0.76); Snakegourd Fruit + Longstamen Onion Bulb + Pinellia Tuber + Dried Tangerine peel + Largehead Atractylodes Rhizome + Platycodon Root (ADR = 0.658568). Conclusion. This study initially optimized prescriptions for UA based on POMDP, which can be used as a reference for further development of UA prescription in Chinese herb medicine. PMID:24078826

  20. Adaptation and validation of the Iranian version of Angina Pectoris characteristics questionnaire.

    Science.gov (United States)

    Najafi-Ghezeljeh, Tahereh; Ekman, Inger; Nikravesh, Mansoureh Yadavar; Emami, Azita

    2008-12-01

    Research aimed at evaluating Angina Pectoris (AP) symptoms in patients with Coronary Heart Disease (CHD) requires a comprehensive assessment tool applicable to this population. Because no single existing measure assessed the full range of symptom characteristics important to our study, we combined two measures (the modified Rose Questionnaire (MRQ), and the Short Form-McGill Pain Questionnaire (SF-MPQ) and added one item to examine specific aspects of AP symptoms (Accompanying Symptom Checklist). The purposes of this study are: (i) to describe the process of translating the SF-MPQ, MRQ and accompanying symptom checklist from English to the Farsi language; and (ii) to evaluate substantial psychometric works (content and construct validity) for the entire instrument and each part of it (SF-MPQ, MRQ and accompanying symptom checklist). A cross-cultural adaptation of the instrument was carried out before developing the final version of it. To these ends, one hundred and 10 CHD patients with AP were assessed by this hybrid measure in an initial study. An analysis of the results indicated that a content valid instrument had been developed. There was a significantly high correlation between scores in the SF-MPQ and there were associations between items in the MRQ. The Iranian version of AP characteristics questionnaire is valid; it is capable of describing characteristics of AP symptoms. However, the reliability of the instrument needs to be assessed through further research. PMID:19126076

  1. Vasospastic angina pectoris complicated by acute myocardial infarction and complete atrioventricular block

    Directory of Open Access Journals (Sweden)

    Pavlović Milan

    2011-01-01

    Full Text Available Background. A prolonged coronary artery spasm with interruption of coronary blood flow can lead to myocardial necrosis and increase of cardiospecific enzymes and can be complicated with cardiac rhythm disturbances, syncopc, or even sudden cardiac death. Case report. A 55-year old male felt a severe retrosternal pain when exposing himself to cold weather. The pain lasted for 20 minutes and was followed by the loss of conscience. Electrocardiogram (ECG showed a complete antrioventricular (AV block with nodal rhythm and marked elevation of ST segment in inferior leads. Electrocardiogram was soon normalized, but serum activities of cardiospecific enzymes were increased. Coronarography showed normal findings for the left coronary artery and a narrowing at the middle part of the right coronary artery, which disappeared after intracoronary application of nitroglycerine. The following therapy was prescribed: Diltiazem, Amlodipin, Isosorbid mononitrate, Molisdomin, Atrovastatin, Aspirin and Nitroglycerine spray. After 7 months medicaments were abandoned and the patient experienced again reccurent chest pain episodes at rest. Transitory ST segment elevation was recorded in inferior leads of ECG, but without increase of cardiospecific enzymes serum activities. After restoration of the medicament therapy anginal episodes ceased. Conclusion. Coronary dilators in maximal doses can prevent attacks of vasospastic angina.

  2. Therapeutic efficacy of a new transdermal system containing nitroglycerin in patients with angina pectoris.

    Science.gov (United States)

    Georgopoulos, A J; Markis, A; Georgiadis, H

    1982-01-01

    The results of a placebo-controlled, double-blind cross-over study in 13 patients with angina pectoris demonstrated that daily application of a newly developed, transdermal therapeutic system for the administration of nitroglycerin (NTG-TTS) over a period of 14 days reduced the daily frequency of anginal attacks by 67%, and the daily consumption of nitrates by 63%. Systolic and diastolic blood pressures were significantly lowered by 10 mmHg and 7.5 mmHg, respectively. The exercise-induced increase in blood pressure was not influenced by NTG-TTS, but it occurred at a lower level. Heart rate was not increased by NTG-TTS, either at rest or upon exercise. Exercise-induced depression of the ST segment diminished by about 50%, and anginal attacks were distinctly less severe and of shorter duration NTG application. Development of tolerance was not detected; on the contrary, the anti-anginal effect was more pronounced in the second than in the first week of medication. NTG had no effect on haematological parameters or blood chemistry, and methaemoglobin formation was not observed. Cutaneous tolerability of the system was good and its application posed no major problem. PMID:6813126

  3. Hemodynamic effects of metoprolol and nifedipine in angina pectoris measured by isotope technique

    Energy Technology Data Exchange (ETDEWEB)

    Bostroem, P.A.

    1988-01-01

    In order to evaluate the therapeutic effects of metoprolol, nifedipine, and their combination, 11 patients with secondary angina pectoris and with thallium tomographic findings indicating coronary artery disease were studied before and after these three treatment regimes in a single-blind cross-over study. The therapeutic effect was measured by standardized working test and isotope angiocardiography, which enabled evaluation of left ventricular ejection fraction, stroke volume, and phase analysis of left ventricular contraction. Treatment with metoprolol and combination therapy increased work performance. Ejection fraction did not differentiate the treatment regimes, whereas stroke volume was significantly lower at work and heart rate higher at rest and at work during nifedipine treatment compared to either metoprolol or combination treatment (p less than 0.05). Cardiac output was significantly reduced during nifedipine and metoprolol treatment during work (p less than 0.05). Phase improved after all therapeutic regimes, but reached significance only during the metoprolol treatment period at rest (p less than 0.05).

  4. Hemodynamic effects of metoprolol and nifedipine in angina pectoris measured by isotope technique

    International Nuclear Information System (INIS)

    In order to evaluate the therapeutic effects of metoprolol, nifedipine, and their combination, 11 patients with secondary angina pectoris and with thallium tomographic findings indicating coronary artery disease were studied before and after these three treatment regimes in a single-blind cross-over study. The therapeutic effect was measured by standardized working test and isotope angiocardiography, which enabled evaluation of left ventricular ejection fraction, stroke volume, and phase analysis of left ventricular contraction. Treatment with metoprolol and combination therapy increased work performance. Ejection fraction did not differentiate the treatment regimes, whereas stroke volume was significantly lower at work and heart rate higher at rest and at work during nifedipine treatment compared to either metoprolol or combination treatment (p less than 0.05). Cardiac output was significantly reduced during nifedipine and metoprolol treatment during work (p less than 0.05). Phase improved after all therapeutic regimes, but reached significance only during the metoprolol treatment period at rest (p less than 0.05)

  5. Nitric Oxide Synthetic Pathway in Patients with Microvascular Angina and Its Relations with Oxidative Stress

    Directory of Open Access Journals (Sweden)

    Benedetta Porro

    2014-01-01

    Full Text Available A decreased nitric oxide (NO bioavailability and an increased oxidative stress play a pivotal role in different cardiovascular pathologies. As red blood cells (RBCs participate in NO formation in the bloodstream, the aim of this study was to outline the metabolic profile of L-arginine (Arg/NO pathway and of oxidative stress status in RBCs and in plasma of patients with microvascular angina (MVA, investigating similarities and differences with respect to coronary artery disease (CAD patients or healthy controls (Ctrl. Analytes involved in Arg/NO pathway and the ratio of oxidized and reduced forms of glutathione were measured by LC-MS/MS. The arginase and the NO synthase (NOS expression were evaluated by immunofluorescence staining. RBCs from MVA patients show increased levels of NO synthesis inhibitors, parallel to that found in plasma, and a reduction of NO synthase expression. When summary scores were computed, both patient groups were associated with a positive oxidative score and a negative NO score, with the CAD group located in a more extreme position with respect to Ctrl. This finding points out to an impairment of the capacity of RBCs to produce NO in a pathological condition characterized mostly by alterations at the microvascular bed with no significant coronary stenosis.

  6. Three Vessel Coronary Cameral Fistulae Associated with New Onset Atrial Fibrillation and Angina Pectoris

    Directory of Open Access Journals (Sweden)

    Murat Yuksel

    2014-01-01

    Full Text Available Coronary cameral fistulas are abnormal communications between a coronary artery and a heart chamber or a great vessel which are reported in less than 0.1% of patients undergoing diagnostic coronary angiography. All three major coronary arteries are even less frequently involved in fistula formation as it is the case in our patient. A 68-year-old woman was admitted to cardiology clinic with complaints of exertional dyspnea and angina for two years and a new onset palpitation. Standard 12-lead electrocardiogram revealed atrial fibrillation (AF with a ventricular rate of 114 beat/minute and accompanying T wave abnormalities and minimal ST-depression on lateral derivations. Transthoracic echocardiographic examination was normal except for diastolic dysfunction, minimally mitral regurgitation, and mild to moderate enlargement of the left atrium. Sinus rhythm was achieved by medical cardioversion with amiodarone infusion. Coronary angiography revealed diffuse and multiple coronary-left ventricle fistulas originating from the distal segments of both left and right coronary arterial systems without any stenosis in epicardial coronary arteries. The patient’s symptoms resolved almost completely with medical therapy. High volume shunts via coronary artery to left ventricular microfistulas may lead to increased volume overload and subsequent increase in end-diastolic pressure of the left ventricle and may cause left atrial enlargement.

  7. Alternativas en la enseñanza de las Matemáticas en la Educación Primaria

    OpenAIRE

    Fernández Verdú, Ceneida; Llinares Ciscar, Salvador

    2015-01-01

    Este libro presenta alternativas a la enseñanza de las Matemáticas en la Educación Primaria desarrolladas por estudiantes para maestro en la asignatura optativa “Taller de Matemáticas en Educación Primaria” del Grado de Maestro en Educación Primaria de la Universidad de Alicante durante el curso 2013/14. La idea que subyace a este planteamiento es que los estudiantes para maestro pueden aprender a desarrollar formas alternativas de enseñar matemáticas para implicar a los niños y niñas en su a...

  8. Leer es un buen plan. Un proyecto para animar a leer en Educación Primaria

    OpenAIRE

    Díaz Quintanilla, Ángela

    2014-01-01

    RESUMEN: Con el presente trabajo se pretende profundizar en la Animación a la Lectura en Educación Primaria, entendiendo la lectura no solo como la habilidad de decodificación de grafías, sino como algo placentero. Se plantea una propuesta de Proyecto de Animación a la Lectura para Educación Primaria (EP). En primer lugar, se realiza una presentación de los aspectos y bases teóricas sobre el aprendizaje de la competencia lectora, en la que se evidencia la importancia de trabajar este tema en ...

  9. Estrategia y táctica en la Educación Primaria. Pensamiento táctico

    OpenAIRE

    Saquero Rodríguez, Víctor Manuel

    2014-01-01

    El desarrollo del pensamiento táctico en el alumnado de Educación Primaria supone un progreso en su proceso madurativo, pues aprenden a organizarse y a descentrarse, mejoran el trabajo en equipo y el respeto hacia los iguales. Con este trabajo se pretende analizar el desarrollo de un proceso educativo con alumnado de educación primaria en torno a las posibilidades y limitaciones de desarrollo del pensamiento táctico con juegos de invasión sin móvil (juegos de persecución).

  10. Un acercamiento curricular en la enseñanza de la Historia en Primaria: La Edad Media

    OpenAIRE

    Abril Frontela, Patricia

    2013-01-01

    El Trabajo de Fin de Grado que presento a continuación tiene como intención plantear una propuesta de trabajo tanto en el aula como fuera de ella basada en la enseñanza de la historia, y en concreto de la Edad Media, mediante Tic u otros medios, en el sexto curso de Educación Primaria. Consiste en un diseño curricular para la enseñanza de la Historia, y más concretamente de la Edad Media en 6º curso de Primaria.

  11. Quimicuentos : Narración de la química cotidiana para alumnos de escuelas primarias

    OpenAIRE

    Hernández, Sandra Analía; Borel, María Cecilia; Sanna, Ana Eugenia

    2012-01-01

    El presente trabajo detalla la implementación, el desarrollo, y las primeras conclusiones obtenidas del proyecto de extensión Quimicuentos. Narración de la química cotidiana para alumnos de escuelas primarias. Con el propósito de acercar al alumno/a de la escuela primaria a conceptos y procesos químicos que son parte de la vida cotidiana y cuya aprehensión resulta importante tanto para su salud como para su desenvolvimiento como ciudadano, trabajamos interdisciplinariamente desde Química, Cie...

  12. El uso de textos literarios en lengua inglesa en centros de educación primaria de Guadalajara

    OpenAIRE

    Jiménez Villacorta, Patricia

    2015-01-01

    Esta tesis tiene como fin conocer de primera mano cuál es la realidad del uso de textos literarios en las aulas de Primaria (materiales, estrategias didácticas, actividades), así como ofrecer un marco y unos recursos didácticos para la utilización de la literatura en la enseñanza de inglés en los niveles más básicos. En este caso, se ha escogido como ámbito de estudio los colegios de Educación Infantil y Primaria de Guadalajara capital, por considerar que es una muestra representativa. El est...

  13. Evaluation of Role of C-Reactive Protein Level on Cardiovascular Events During 14 Days after Admission of Patients with Unstable Angina in the Ekbatan Hospital, Hamadan, 2002

    Directory of Open Access Journals (Sweden)

    B. Naghsh Tabrizi

    2007-01-01

    Full Text Available Introduction & Objective: Unstable angina is in the center of spectrum from chronic stable angina to acute myocardial infarction. Due to high prevalence of unstable angina, it is important to find a factor that predicts prognosis and management modality. We decided to measure CRP level for the items that mentioned above.Materials & Methods: This study was a cross-sectional study that 138 patients who were admitted with unstable angina in the CCU and cardiac ward of Ekbatan Hospital in Hamedan were considered for measuring CRP level. Age, sex, period of disease, and left ventricular ejection fraction percentile were worked out. After quantitative CRP measuring and 14 days follow up, the questionnaire was completed.Results: CRP levels were 116.3 and 124.3 ng/ml in the patients with and without cardiovascular events (whole events respectively during 14 days follow up. Recurrent unstable angina, myocardial infarction and mortality rate were higher in the patients with elevated level of CRP but need to perform coronary angiography was lower.Conclusion: CRP level had no correlation with occurrence of cardiovascular events (whole events during 14 days follow up.

  14. Razonamiento proporcional: conocimiento especializado de contenido matemático en estudiantes para maestro de primaria

    OpenAIRE

    Buforn, Ángela; Fernández, Ceneida

    2013-01-01

    Este estudio examina el conocimiento especializado de contenido matemático de un grupo de estudiantes para maestro de Educación Primaria en el ámbito del razonamiento proporcional. Los resultados muestran que los estudiantes para maestro tienen dificultades en identificar situaciones no proporcionales, en reconocer la unidad en contextos de medida con el significado parte-todo y en usar el significado multiplicativo de la idea de operador. Estos resultados aportan información de las carac...

  15. Geometría para futuros profesores de primaria: experiencias con el tangram chino

    OpenAIRE

    Fernández, Teresa

    2003-01-01

    Este artículo tiene como objetivo presentar una experiencia sobre didáctica de la geometría llevada a cabo en la facultad de Ciencias de la Educación de Santiago de Compostela con alumnos de la especialidad de maestro en educación primaria. En ella se utilizó un juego de disección (el tangram chino) como base para la realización de una serie de actividades que tienen un objetivo múltiple: concienciar a los alumnos sobre las ventajas del uso de un material manipulativo para el estudio de propi...

  16. Experiencia de implementación de un modelo de atención primaria

    OpenAIRE

    Ruíz Rodríguez, Myriam; Acosta Ramírez, Naydú; Rodríguez Villamizar, Laura Andrea; Uribe Rivero, Luz Marina; León Franco, Martha Helena

    2012-01-01

    Objetivo Identificar las dificultades y los factores dinamizadores en la implementación de un modelo de atención primaria en Santander en la última década.Métodos Estudio cualitativo con un enfoque de pluralismo y la triangulación de fuentes y actores, con análisis de crítica del límite y de los valores de los juicios (Boundary critique).  Resultados Según las categorías emergentes derivadas de la apropiación de los atributos del modelo se encuentran problemáticas tanto en aspectos filosófico...

  17. Tipologia textual en 4º curso de Educación Primaria

    OpenAIRE

    Morejón Reguera, Desiré

    2015-01-01

    El presente trabajo es un estudio realizado en una clase de cuarto de Educación Primaria de un pequeño colegio público, situado en las inmediaciones de Palencia. Dicho estudio refleja el peso que tiene la lengua escrita a lo largo de la etapa escolar y, de ahí, la importancia de ofrecer desde el colegio técnicas y recursos innovadores que favorezcan el aprendizaje significativo, además de fomentar el gusto por la escritura a los alumnos y a las alumnas a través del ejercicio de la motivación....

  18. La enseñanza de la literatura fracesa en Educación Primaria

    OpenAIRE

    González Gómez, Esmeralda

    2013-01-01

    Este trabajo analiza los resultados obtenidos en una clase de Educación Primaria a partir de la puesta en práctica de tres textos perteneciente a la literatura francesa. Concretamente se trata de tres fábulas pertenecientes a la obra Fábulas de Jean de la Fontaine caracterizadas por el empleo de un vocabulario semejante, por presentar una extensión similar y por mostrar un grado de dificultad análogo. Cada uno de los textos ha sido desarrollado con una metodología diferente sur...

  19. Las plantas en los libros de Conocimiento del Medio de 2º ciclo de primaria

    OpenAIRE

    Urones, Carmen; Escobar, Beatriz; Vacas, José Manuel

    2013-01-01

    Se describen y analizan los resultados de un estudio sobre las plantas en los libros de texto de Conocimiento del Medio de tercer y cuarto curso de educación primaria (escolares de 8-10 años). Concretamente: ¿qué deben conocer los niños sobre las plantas?; ¿qué características generales siguen los libros en el planteamiento del tema?; ¿cómo es el tratamiento de los contenidos de conceptos, procedimientos y actitudes sobre plantas?; y ¿cuáles son los objetivos de las actividades de...

  20. El manejo de los comportamientos disruptivos en el aula de Educación Primaria

    OpenAIRE

    Sepúlveda Millán, José M.

    2013-01-01

    En el presente Trabajo Fin de Grado trataremos de abordar los aspectos más importantes y relevante relacionados con los niños y niñas con problemas de comportamiento disruptivo y sus repercusiones dentro del aula de Educación Primaria. Para ello nos basaremos en una propuesta de intervención didáctica, cuyo elemento principal será la observación directa del maestro/a hacia el alumnado. A partir de ahí empezaremos a valorar la situación de grupo-clase a través de unas pruebas de comportamient...

  1. Blended-learning y telepresencia en Educación Primaria

    OpenAIRE

    Manteca-Velasco, Javier

    2014-01-01

    Este estudio investiga el grado de integración de las TIC en las escuelas de Primaria tanto a nivel teórico como empírico para posteriormente plantear una propuesta de intervención basada en blended-learning y telepresencia a través del uso de Tablets y la inclusión de nuevas figuras docentes. A través de la revisión bibliográfica, trataremos de conocer la opinión de expertos en torno al futuro del libro de texto. También analizaremos las posibilidades futuras de una educaci...

  2. Programa de entrenamiento en habilidades sociales con alumnos de educación primaria

    OpenAIRE

    Mohamed, L.; Mohamed, N.; Seijo, D.

    2005-01-01

    En esta comunicación nos centramos en el entrenamiento de las habilidades sociales, así como su enseñanza y aprendizaje. En este trabajo se presentan las diferentes sesiones diseñadas para entrenar este tipo de habilidades llevadas a la práctica con niños de educación primaria de dos centros educativos de la Ciudad Autónoma de Melilla. Gracias a las características de la población intercultural de esta ciudad, nos interesa conocer los efectos de este entrenamiento en función del origen cultur...

  3. Supervivencia de pacientes con insuficiencia cardiaca en atención primaria

    OpenAIRE

    Antonio Sarría-Santamera; Francisco Javier Prado-Galbarro; María Auxiliadora Martín-Martínez; Rocío Carmona; Ana Estela Gamiño Arroyo; Carlos Sánchez-Piedra; Sofía Garrido Elustondo; Isabel del Cura González

    2015-01-01

    Objetivo: Describir la supervivencia de los pacientes con insuficiencia cardiaca (IC) con seguimiento en atención primaria (AP) y analizar el efecto del sexo, edad, factores clínicos, de utilización de servicios y nivel de renta, en la supervivencia. Diseño: Estudio observacional longitudinal de una cohorte retrospectiva de pacientes a partir de la historia clínica electrónica. Emplazamiento: Área 7 de AP de la Comunidad de Madrid. Participantes: Pacientes mayores de 24 años con una ...

  4. La teoría del desarrollo cognitivo de Piaget aplicada en la clase de Primaria

    OpenAIRE

    Castilla Pérez, María Francisca

    2014-01-01

    El presente trabajo Fin de Grado se encuentra destinado a realizar un estudio de la Teoría del desarrollo cognitivo de Jean Piaget, cuyo entendimiento es fundamental tanto para comprender al niño de hoy como para educar al adulto del mañana. Esta teoría se pondrá en práctica a través de la propuesta de un proyecto de trabajo en el aula, donde se recomendarán actividades fundamentadas en el constructivismo de Piaget para trabajar con un grupo de alumnos de segundo de educación primaria. Basánd...

  5. Acercamiento al folklore de Castilla y León en las aulas de primaria

    OpenAIRE

    Hernando Arce, José Luis

    2012-01-01

    Nadie pone en duda la importancia que encierra el folklore no solo como base para conocer mejor nuestra propia cultura tradicional sino que nos enseña a comprender otras diversidades culturales. Se requiere que en la etapa de primaria se potencie en los niños y niñas el deseo de aprender aspectos relacionados con su folklore como es el caso de la música tradicional de Castilla y León en donde, actualmente, nos están invadiendo otras clases de músicas, dejando de lado lo más cercano a nuestro...

  6. El mutismo selectivo en el aula de Primaria. Propuesta de intervención

    OpenAIRE

    Carro, Sandra

    2012-01-01

    Durante el desarrollo infantil las dificultades de aprendizaje y los problemas relacionados con el retraso madurativo suelen ser los más habituales; sin embargo, existen otros, más ocultos que a menudo pasan inadvertidos o no se les otorga la suficiente importancia. Uno de estos conflictos es el trastorno de la conducta denominado Mutismo Selectivo. Este trabajo tiene como objetivo ayudar a los maestros de educación Primaria a realizar una detección precoz, presentándoles modelos de instru...

  7. Trastornos leves en el lenguaje y habla. Formación para maestros de primaria

    OpenAIRE

    Simoes, Susana

    2012-01-01

    Los trastornos del lenguaje y habla pueden causar retraso escolar o llegar a aislar a los alumnos de su entorno educativo o social. Pese a que la normativa vigente exige desarrollar en nuestros alumnos la Competencia lingüística, los maestros no reciben formación al respecto y no saben cómo actuar ante sus alumnos con déficits en el habla o lenguaje. Así, el objetivo general de este programa de intervención es formar a los Maestros de Primaria sobre los problemas del lenguaj...

  8. Propuestas educativas para la formación de mentalidades emprendedoras en la etapa de Primaria

    OpenAIRE

    Coscujuela-Palau, María Rosa

    2012-01-01

    Este trabajo de fin de grado es una investigación de las propuestas educativas más importantes que hay en la educación primaria en España para la formación de actitudes emprendedoras en edades tempranas. Estas propuestas están dispersas, sin conexión entre ellas en la red, lo que debilita su eficacia y propósitos. El motivo de este estudio es investigar esas propuestas educativas, seleccionar las más interesantes bajo un criterio específico, ordenarlas para que el lector pueda tener una id...

  9. Particiones de todos continuos elaboradas por maestros de primaria en formación

    OpenAIRE

    Carrillo, Marcela; Valdemoros, Marta Elena

    2011-01-01

    Esta investigación de carácter exploratorio y de corte cualitativo, concierne al aprendizaje y enseñanza de las relaciones de equivalencia entre fracciones y los procesos de partición. Los sujetos del estudio son maestros en formación del tercer semestre de la licenciatura en Educación Primaria, impartida en la Escuela Normal de la Ciudad de México. Los instrumentos metodológicos empleados son: dos cuestionarios, observación participante y entrevistas, para elaborar estudio de casos. En este ...

  10. La Lectura de textos multimodales en el contexto de proyectos de aprendizaje en la Escuela Primaria

    OpenAIRE

    Rojas López, Dora Elia

    2014-01-01

    La aparición del texto multimodal vía internet principalmente, ha obligado a repensar los conceptos de lectura y comprensión lectora y a estudiar los retos didácticos que tiene el profesor en el proceso de incorporación de este tipo de textos en el aula. En el caso de la escuela primaria mexicana las reiteradas reformas educativas implementadas en los últimos años no han tenido el impacto esperado en mejorar las prácticas de lectura en el aula y en consecuencia el desarrollo de las compete...

  11. Los libros de texto en la escuela primaria y sus implicaciones en la lectura

    OpenAIRE

    Marisela Partido Calva

    2007-01-01

    Los libros de texto en el nivel básico constituyen una herramienta cognoscitiva importante; son utilizados por maestros y alumnos para mediar sus procesos formativos, ya que generan estrategias pedagógicas, cognitivas y culturales. En este artículo se analiza la propuesta curricular institucional planteada en la escuela primaria para la enseñanza del español, en términos de los objetivos, contenidos y actividades de aprendizaje. Se describe la práctica de algunos docentes en torno a la enseña...

  12. IMPORTANCIA DE LA ACTIVIDAD MOTRIZ EN LOS PROCESOS LECTOESCRITORES EN UN GRUPO DE PRIMARIA.

    OpenAIRE

    Cabezas-Pajares, Ana Belén

    2013-01-01

    El presente trabajo centra su investigación en la repercusión que puede tener el desarrollo motriz a la hora de llevar a cabo una correcta escritura y un adecuado dominio de la lectura, tanto de la rapidez como de la comprensión lectora. Para ello se han evaluado en un grupo de alumnos de 4º de Educación Primaria, habilidades motrices y procesos lectoescritores, a través de cuestionarios y tablas de observación. Los resultados ponen de manifiesto la relación existente ent...

  13. Motricidad, lectura y escritura: estudio en una muestra de alumnos de segundo ciclo de Ed. Primaria.

    OpenAIRE

    Marini-Romero, María Ángeles

    2012-01-01

    La finalidad de este trabajo es explorar los procesos de lectura y escritura y relacionarlos con la motricidad gruesa así como con la destreza manual. Para ello, se eligió una muestra de 30 sujetos de tercero de primaria de dos colegios, uno público y otro concertado con carácter religioso, a quienes se aplicaron una serie de pruebas como: Velocidad y Comprensión lectora y Motricidad gruesa y Destreza manual, a las que los niños/as tuvieron que dar respuesta a las cuestiones planteadas sobre ...

  14. Tratamiento de la educación sexual en escuelas primarias en el sur de Brasil

    OpenAIRE

    Denise Quaresma da Silva

    2014-01-01

    Objetivo: analizar el tratamiento de la educación sexual en escuelas públicas municipales de enseñanza primaria. Métodos: estudio descriptivo y transversal con metodología cuantitativa-cualitativa donde la entrevista semiestructurada se utilizó como instrumento de recogida de información. La entrevista se aplicó entre marzo y diciembre del año 2012 a una muestra no probabilística de 82 docentes de las 56 escuelas públicas municipales de Novo Hamburgo. Para el examen de las entrevistas se util...

  15. Análisis de la Incapacidad Temporal desde la Atención Primaria

    OpenAIRE

    Eugenio Fernández Escalada

    2014-01-01

    La IT es una de las principales prestaciones del Sistema Nacional de la Seguridad Social. En el control y gestión de dicha prestación estamos implicados muchos profesionales de distintas entidades: Atención Primaria, Atención Especializada, Inspección Médica, INSS, Mutuas, etc. No debemos obcecarnos en ver solo los problemas que nos genera la gestión de la IT desde nuestro punto de vista. Si realmente queremos que la gestión de la IT sea lo más eficiente posible, la colaboración entre todos e...

  16. Desarrollo musical en Educación Primaria: una perspectiva emocional

    OpenAIRE

    Irisarri Labat, Itziar

    2015-01-01

    Actualmente la escuela dedica la mayor parte del tiempo a trabajar contenidos que requieren de los aspectos cognitivos o intelectuales del alumnado de Primaria. No obstante, la faceta emocional de estos niños queda muchas veces olvidada y no se presta demasiada atención a sus sentimientos ni emociones. La asignatura de música es una de las materias que no solo proporciona un crecimiento intelectual, sino también emocional, pues las actividades que se llevan a cabo en el aula favorecen enormem...

  17. Creatividad e Inteligencias Múltiples: diferencias según sexo y curso en Primaria y Secundaria

    OpenAIRE

    Escortell-Sánchez, Raquel

    2013-01-01

    El modelo de escuela tradicional está siendo, en la actualidad, poco a poco sustituido por ideales educativos centrados en el alumno, no obstante, todavía queda mucho camino por recorrer en este sentido. El presente estudio se enmarca dentro de la relación recíproca entre neuropsicología y educación y pretende aportar datos que guíen en la elaboración de estrategias de enseñanza-aprendizaje. Con una muestra de 222 escolares de Primaria y Secundaria se pretende comprobar la existencia o no de ...

  18. El acoso escolar en Educación Primaria en la provincia de Huelva

    OpenAIRE

    Ávila Fernández, José Antonio

    2013-01-01

    El resumen que a continuación se presenta, es el reflejo del trabajo de tesis doctoral realizado bajo el título «El Acoso Escolar en Educación Primaria en la Provincia de Huelva». En los últimos años ha existido una preocupación social en relación al tema de la violencia escolar, reconociéndose como un problema común. Los medios de comunicación se han ocupado de difundir situaciones límites relacionadas con e! comportamiento de escolares; a nivel internacional se ha afrontado la investigac...

  19. Servicios farmacéuticos en la atención primaria en salud

    Directory of Open Access Journals (Sweden)

    Rafael Mota PINHEIRO

    2010-12-01

    Full Text Available Este artigo aborda las bases políticas y conceptuales de la atención farmacéutica en el Brasil, a partir de las definiciones básicas de los términos relacionados con el cuidado a la salud. Enfoca la relación y el papel de la atención farmacéutica con la atención primaria, y los principales retos e factores críticos.

  20. Enfermería ante los cuidados paliativos en Atención Primaria

    OpenAIRE

    Fuentes Fernández, Lourdes

    2013-01-01

    A través de una revisión bibliográfica se expone la figura del enfermo terminal y los cuidados paliativos prestados por el personal sanitario y en particular la enfermera de atención primaria. Se presentan los acontecimientos históricos más relevantes en torno a la a evolución histórica de los cuidados paliativos; a quien van prestados, las características, los objetivos y las diferentes fases por las que pasa el enfermo terminal. La atención sanitaria a estos pacientes se organiza desde los ...

  1. Propuesta del tratamiento de las emociones en el aula de Educación Primaria

    OpenAIRE

    Fernández Santos, Beatriz

    2014-01-01

    La propuesta desarrollada en este Trabajo Fin de Grado, pretende integrar el tratamiento de las emociones y su desarrollo, en el día a día del aula del primer ciclo de Educación Primaria, por la importancia que este tipo de inteligencia supone en el desarrollo integral de la persona. Pretendo como docente, gestionar mis propias emociones por lo que eso supone de transferible en el contacto con los demás, a la vez que dotar al alumnado de herramientas que les sirvan para el l...

  2. El ciclismo y la educación vial en Educación Primaria

    OpenAIRE

    Barrero Gozalo, María

    2014-01-01

    La etapa de Educación Primaria es importante para la formación integral de los alumnos, ya que esta les ayudará a desenvolverse en el mundo en el que viven. Por ese motivo el alumnado debe conocer las diferentes formas que existen para mantener un buen estado de salud. La propuesta desarrollada a continuación muestra como mantenerse saludable así como un modo innovador de conocer elementos que nos rodean. Para ello se usa la bicicleta, ya que esta se presenta no solo como un me...

  3. Promover el placer por la lectura en 4º de Educación Primaria

    OpenAIRE

    Singer-Grisolía, Paula

    2015-01-01

    Este trabajo parte de un enfoque teórico práctico para incidir en la metodología empleada en una escuela y promocionar la lectura por placer en 4º de Educación Primaria. Se analizan teorías que permitirán enriquecer una práctica activa, participativa y basada en la realidad de los alumnos. Se realizan encuestas y entrevistas a los niños y niñas y a las maestras para conocer por un lado el bagaje y gustos lectores de los alumnos y por otro lado la praxis desarrollada por las ...

  4. Promoviendo la dieta mediterránea en Educación Primaria

    OpenAIRE

    Benavente Florido, Estefanía

    2015-01-01

    Este trabajo fin de grado trata de ofrecer una propuesta didáctica que permita acercar al alumnado de Educación Primaria al conocimiento de la dieta mediterránea y los beneficios de ésta. Es crucial que el alumnado reflexione sobre su propia alimentación y los beneficios que supone adoptar la dieta mediterránea. Su propia concienciación y aprendizaje en torno a la dieta mediterránea, le permitirá explicar a alumnado de otros cursos de Ed...

  5. Toma de decisiones clínicas en atención primaria

    OpenAIRE

    Antonio Moncada; María Sofía Cuba

    2013-01-01

    El profesional del primer nivel de atención necesita estar altamente calificado en tomar decisiones médicas con el debido respaldo científico, aplicado a una metodología ordenada y eficiente a la hora de tomar una decisión. De esta manera llegamos a un diagnostico razonado, generando satisfacción en el usuario. A este método lo denominamos toma de decisiones clínicas en atención primaria. Durante el proceso de toma de decisión médica surge la incertidumbre, que en medicina gira en torno a la ...

  6. La escalada en pared artificial (rocódromo) en Educación Primaria

    OpenAIRE

    Ibáñez Gutiérrez, Luis Alejandro

    2015-01-01

    Con este Trabajo de Fin de Grado (TFG) pretendo mostrar un método de iniciación a la práctica de una Actividad Física en el Medio Natural (AFMN), como es la escalada, adaptada al centro. Este planteamiento consiste en la programación de una unidad didáctica adaptada al centro CEIP Jorge Manrique de Palencia, considerando los recursos materiales y espa-ciales del centro, y destinado a los alumnos de 5º y 6º de Primaria. Esta unidad consta de 4 sesiones en el gimnasio y la programación de un...

  7. CULTIVAR AGROECOLOGÍA EN ESCUELAS PRIMARIAS DE MONTEVIDEO. PROGRAMA HUERTAS EN CENTROS EDUCATIVOS

    OpenAIRE

    Bellenda, Beatriz; Faroppa, Stella; García, Maria; Linari, Gabriela; Lorenzo, Regina; Meikle, Monica; Vallo, Giselle; Viola, Cristina; Baron, Josefina; Andino, Mariana; Correa, Elizbeth

    2013-01-01

    El Programa Huertas en Centros Educativos (PHCE) es una experiencia que desarrollan conjuntamente la Intendencia de Montevideo, la Administración Nacional de Enseñanza Pública y la Universidad de la República, desde el año 2005. Se basa en la docencia, instalación y seguimiento de huertas agroecológicas en 49 escuelas primarias de Montevideo ubicadas en zonas de vulnerabilidad social. Trabajan en él, 35 orientadores de huerta que participan junto a unos 14.000 niños y 450 maestros en forma di...

  8. Burnout y trabajo en equipo en los profesionales de Atención Primaria

    OpenAIRE

    Maite Vilà Falgueras; Carlota Cruzate Muñoz; Francesc Orfila Pernas; Joan Creixell Sureda; María Pilar González López; Josep Davins Miralles

    2015-01-01

    Objetivo: Estimar la prevalencia de burnout y percepción de trabajo en equipo en los equipos de Atención Primaria (EAP) de Barcelona ciudad. Diseño: Transversal multicéntrico. Emplazamiento: EAP del Institut Català de la Salut (ICS) en Barcelona. Participantes: Trabajadores fijos e interinos, de todas las categorías profesionales de 51 EAP (N = 2398). Respondieron 879 (36,7%). Mediciones: Se envió por correo electrónico el cuestionario «Maslach Burnout Inventory», con las dimensio...

  9. TRANSFERENCIA DE INTELIGENCIAS MÚLTIPLES EN ALUMNOS CON AUTISMO DE EDUCACIÓN PRIMARIA

    OpenAIRE

    Plágaro-Martos, Miriam

    2015-01-01

    El presente estudio de investigación está basado en la Teoría de la Inteligencias Múltiples, descrita por Howard Gardner en 1983. Así como en el concepto de inteligencia emocional, acuñado por Daniel Goleman en 1995. Estudiamos el nivel de desarrollo en cada inteligencia múltiple, en alumnos diagnosticados con Trastorno de Espectro Autista, autismo. Componiéndose la muestra de estudio por 30 alumnos con dicho diagnóstico, escolarizados en la etapa educativa de educación primaria. Para el desa...

  10. Incidencia de los Movimientos Oculares en el proceso lector de alumnos de Primer ciclo de Primaria.

    OpenAIRE

    Alejo-Ramos, Cristina

    2013-01-01

    Los movimientos oculares en la lectura son importantes para el proceso de aprendizaje de los niños. Este trabajo de investigación tiene como objetivo, conocer la influencia de los movimientos oculares en la lectura. Para ello se llevó a cabo un estudio, con una muestra de 30 alumnos del Primer ciclo de Primaria, es decir, Primero y Segundo, del mismo centro educativo. Una vez que se realizaron las pruebas oportunas, se pudo comprobar cómo estaban relacionadas motricidad ocular y lectura...

  11. RELACIÓN ENTRE MOVIMIENTOS OCULARES Y LECTURA EN ALUMNOS DE 2º DE PRIMARIA

    OpenAIRE

    Cabanillas-Centeno, María Isabel

    2013-01-01

    El presente trabajo tiene como objetivo comprobar la relación existente entre los movimientos oculares y el rendimiento en lectura. Para ello se ha llevado a cabo un estudio con una muestra de 56 niños de 2º de primaria, pasando pruebas para evaluar tanto el movimiento ocular durante la lectura, como el nivel de velocidad y comprensión lectora. Los resultados obtenidos demuestran que los alumnos que presentan dificultades en los movimientos oculares, obtienen puntuaciones más bajas en compren...

  12. I Congreso Nacional: La Ciencia en la Educación Infantil y Primaria

    OpenAIRE

    Gómez Díaz, Mª José; López Álvarez, José Manuel; Olmos Romera, Ricardo; Delgado-Barrio, Gerardo; Tiemblo Ramos, Alfredo; Yuste Llandres, Manuel; López Sancho, José M.; Fernández Rañada, Antonio; Perales Palacios, Francisco Javier; Páramo Sureda, Ernesto; López, Javier; Pla, María; Cano, Elena; Lorenzo, Nuria; Pla, Inma

    2001-01-01

    Resumen de las ponencias, comunicaciones y posters del I Congreso Nacional "La Ciencia en la Educación Infantil y Primaria" celebrado en Granada en septiembre de 2001. El objetivo de este congreso es propiciar el acercamiento del mundo de la Ciencia al de la enseñanza en las primeras etapas. La enseñanza de la Ciencia, concebida como parte de la cultura, es un elemento fundamental de los contenidos con los que un niño tiene que contar para afrontar un mundo de creciente complejidad, en el que...

  13. Estrategias de futuros profesores de primaria en problemas aditivos con números negativos

    OpenAIRE

    Almeida, Rut; Bruno, Alicia

    2013-01-01

    Este trabajo analiza las estrategias de resolución de problemas aditivos simples con números negativos por parte de futuros profesor de enseñanza primaria. Los resultados muestran seis estrategias diferentes que dependen de la dificultad del problema y en especial, de la posición de la incógnita. Los futuros profesores usan números negativos en los problemas que les resultan más sencillos y recurren a otras estrategias en los problemas más complejos. Las respuestas evidencian dificult...

  14. Abordaje de la artrosis desde la atención primaria

    OpenAIRE

    Lafuente Navarro, Ana; Lafuente Navarro, Cándida

    2006-01-01

    La artrosis es una enfermedad crónica prevalente asociada a dolor, discapacidad y empeoramiento de la calidad de vida. Las herramientas de apoyo que utilizamos a menudo en atención primaria para el abordaje de esta patología son las guías de la práctica clínica. En estas guías hay recomendaciones basadas en la evidencia,que ayudan al profesional en su práctica habitual a tomar la decisión más adecuada para cada paciente. A su vez permiten actuar de una forma conjunta y sincronizada a los dife...

  15. Tecnologías informáticas y cambios organizativos en centros de Primaria

    OpenAIRE

    Peirats Chacón, José; Ángel SAN MARTÍN ALONSO; Sales Arasa, Cristina

    2008-01-01

    En este artículo reflexionamos sobre los procesos de cambio experimentados por las organizaciones educativas, centrando el foco de atención en los centros de Primaria. Cambios propiciados a partir de la introducción e integración de las tecnologías informáticas en sus tareas, tanto pedagógicas como administrativas. Las consideraciones y conclusiones defendidas en este artículo, se desprenden tanto de las aportaciones realizadas por los autores que investigan el problema del cambio en las orga...

  16. La influencia de la palabra microbio en las representaciones iniciales de alumnos de primaria

    OpenAIRE

    Mayerhofer B., N.

    2009-01-01

    En esta investigación exploramos las ideas previas de alumnos de primer curso de primaria (6 años) y sus representaciones gráficas y textuales sobre los microorganismos. Para la obtención de los datos llevamos a cabo la unidad didáctica “Higiene y Salud” en dos escuelas de Cerdanyola del Vallès – Barcelona, con la recogida de dibujos que posteriormente fueron analizados en base a métodos cualitativos como las redes sistémicas. Los alumnos han presentado resultados distintos en cada escuela do...

  17. Los efectos del aprendizaje cooperativo en la inclusión en sexto de Primaria

    OpenAIRE

    Ortiz Villanueva, Naiara

    2013-01-01

    En el presente trabajo se busca demostrar la relación entre dos aspectos claves en la educación hoy: la inclusión y los grupos cooperativos. Se parte de una descripción teórica de ambos conceptos, así como de los puntos que los enlazan, para seguir con un estudio empírico llevado a cabo en un centro de Pamplona, San Jorge, en el que se toma como muestra el alumnado de 6º de Educación Primaria, así como el profesorado que lo atiende. Se realiza un estudio comparativo entre alumnos que trabajan...

  18. Hipertensión arterial pulmonar primaria o idiopática

    OpenAIRE

    Yazmín Ravelo-Calzado; Vivian Molina-Cuevas; María de Lourdes Arruzazabala-Valmaña; Daisy Carbajal-Quintana

    2010-01-01

    La hipertensión arterial pulmonar primaria (HAPP) es una enfermedad crónica de causa desconocida que se caracteriza por un incremento de la presión sanguínea media en la arteria pulmonar, mayor de 25 mmHg en reposo o más de 30 mmHg durante el ejercicio. Es una enfermedad que afecta a ambos sexos y no tiene predilección racial. La HAPP sin tratar puede conducir a una insuficiencia ventricular derecha y por consiguiente, a la muerte. La HAPP involucra varios mecanismos subyacentes, dentro de lo...

  19. Algoritmos alternativos para la enseñanza de operaciones en educación primaria

    OpenAIRE

    Ereño-Arrizabalaga, Ane

    2014-01-01

    El área de matemáticas siempre ha sido algo controvertida y en ocasiones abstracta para los alumnos. A través de este trabajo se pretende realizar una aproximación a un apartado de las matemáticas muy investigado como son los algoritmos alternativos existentes, tanto los denominados históricos como los alternativos empleados actualmente, para poder ver sus características y la idoneidad de su aplicación en la educación primaria, frente a los algoritmos tradicionales que actualmente se usan y ...

  20. Clasificación de malformaciones craneales causadas por craneosinostosis primaria utilizando kernels no lineales

    OpenAIRE

    Salvador Ruiz-Correa; Yerania Campos-Silvestre

    2010-01-01

    La craneosinostosis primaria (CP) es una condición patológica asociada a la fusión prematura de una sutura del calvario. La fusión temprana produce malformaciones craneales severas que se asocian frecuentemente con discapacidades cognitivas, del lenguaje, el aprendizaje y el comportamiento social en general. Por estas razones, la CP representa un área de investigación importante que requiere de métodos efectivos para caracterizar la morfología del complejo craneofacial. En este trabajo, se es...

  1. Evaluación de las inteligencias múltiples y estilos de aprendizaje en Primaria

    OpenAIRE

    Brunal-Vergara, Beatriz

    2014-01-01

    En este trabajo de investigación se identificaron los tipos de inteligencias múltiples y los estilos de aprendizaje que predominan en los estudiantes de primaria del colegio Windsor Royal School en la ciudad de Montería capital del departamento de Córdoba en Colombia. La investigación es considerada de corte descriptivo transversal. El objetivo principal fue establecer si existen relaciones entre las inteligencias múltiples y los estilos de aprendizaje. Se emplea un método cuantit...

  2. Escalas de evaluación de riesgo suicida en atención primaria

    OpenAIRE

    Claudia Ximena Rangel-Garzón; María Fernanda Suárez-Beltrán; Franklin Escobar-Córdoba

    2015-01-01

    Antecedentes. El médico de atención primaria debe decidir qué hacer con un paciente que ha atentado contra su vida o manifiesta ideación suicida. Posiblemente puede interconsultar a psiquiatría; sin embargo, ocasionalmente esto se difiere. Objetivo. Encontrar un instrumento de evaluación del riesgo suicida en adultos que pueda ser aplicado por el médico general en el servicio de urgencias. Materiales y métodos. Revisión de la literatura en PubMed con los términos MeSH: ‘suicide', ‘risk assess...

  3. La enseñanza de la historia reciente en Educación Primaria

    OpenAIRE

    Díaz Noriega, Sara

    2015-01-01

    Este trabajo pretende demostrar la importancia de la enseñanza de la historia reciente española como un aspecto esencial que debe adquirir el alumnado de último ciclo de Educación Primaria. Comprender esta parte de la historia fomenta su formación integral ya que, además de adquirir los conocimientos acordes a la materia, permite su formación como ciudadanos activos de la sociedad, además de hacerles partícipes de aspectos sociales de su entorno. Para cumplir con este objeti...

  4. Representaciones sociales de profesores de primaria acerca del niño

    OpenAIRE

    Silvia Domínguez Gutiérrez

    2003-01-01

    Esta investigación coteja las representaciones sociales que sobre el niño tienen los profesores de primaria de una escuela privada personalizada con las de los profesores de una escuela pública tradicional (n=12, seis de cada escuela). Indaga la concepción que tienen del alumno, así como las fuentes de formación e información de mayor influencia en la determinación de la representación del infante. Se utilizó un cuestionario escala Likert para medir la información y la actitud sobre el niño (...

  5. Terapia Familiar Breve y Atención Primaria: Un Caso de Trastorno Somatomorfo

    OpenAIRE

    Nieves Schade; Mark Beyebach; Patricio Torres; Angélica González

    2009-01-01

    En este artículo se presenta un modelo de Terapia Familiar que puede ser útil en la atención primaria para el tratamiento de pacientes somatomorfos o con trastornos somatomorfos. El objetivo fue describir un caso de trastorno somatomorfo y una forma de intervención a través de la Terapia Familiar Breve. El Método incluyo la recogida de la historia clínica y aplicación de la Terapia Familiar Breve por dos profesionales de la salud: psicólogo y médico de familia. Los resultados muestran una dis...

  6. Creando un blog multilingüe en Educación Primaria

    OpenAIRE

    Lozano Eciolaza, Iñigo

    2014-01-01

    Las Tecnologías de la Información y de la Comunicación (TIC) están teniendo una creciente repercusión en nuestra sociedad y también en la escuela, al ser reflejo de esta. En el presente trabajo abordaremos el tema de los blogs, una herramienta cada vez más utilizada en la enseñanza y que, sin embargo, ha sido muy poco estudiada. Primero justificaremos el tema elegido relacionándolo con las competencias del Grado de Magisterio y el currículum de primaria. A continuación, estableceremos el marc...

  7. Estudio bidireccional de la comunicación no verbal en el aula de Primaria

    OpenAIRE

    García Aguilera, Fernando

    2014-01-01

    El aula de Educación Primaria es un espacio de convivencia en el que se producen procesos comunicativos entre el maestro y el alumno. Normalmente recurren a la comunicación verbal, ya sea oral o escrita, para comunicarse, utilizando las palabras como vehículo de expresión. Pero en el aula se producen otras formas de comunicación que transmiten mensajes voluntaria o involuntariamente y que aportan, modifican o incluso contradicen los contenidos del mensaje verbal: gestos, posturas, miradas… To...

  8. Aplicación de un programa emocional en educación primaria

    OpenAIRE

    Padierna Alonso, Virginia

    2012-01-01

    En este proyecto voy a desarrollar un programa de educación emocional, contextualizado para segundo ciclo de educación primaria, con niños que participan en el Plan PROA, partiendo de una situación de desventaja educativa, bien por circunstancias de carácter personal o sociocultural, este programa está orientado a mejorar y enriquecer el proceso educativo del alumno/a. El programa de educación emocional, es un programa de actividades motivadoras que buscan alternativas respondiendo a los ...

  9. Alumnos con Bajo Rendimiento Escolar, los blogs y el tutor de Primaria

    OpenAIRE

    Rico-Sánchez, Jesús David

    2013-01-01

    Teniendo en cuenta el problema que tiene el sistema educativo español con un índice muy elevado de fracaso escolar, se pretendió investigar concretamente sobre los alumnos del sexto curso de Primaria que presentan Bajo Rendimiento Escolar aprovechando los avances tecnológicos existentes en la actualidad y que han penetrado con gran fuerza en la sociedad. Por ello, el problema planteado en este trabajo es estudiar si el potencial motivador, comunicativo y utilitario del Edublog puede ayudar a ...

  10. Deberes escolares y rendimiento académico en Educación Primaria

    OpenAIRE

    Antonio Valle; Irene Pan; José C. Núñez; Pedro Rosário; Susana Rodríguez; Bibiana Regueiro

    2015-01-01

    En este artículo se analiza la relación entre la realización de deberes escolares y el rendimiento académico en una muestra de estudiantes de los tres últimos cursos de Educación Primaria. Las variables vinculadas con la implicación de los alumnos en los deberes escolares fueron el número de deberes realizados, el tiempo dedicado a los deberes y el aprovechamiento del tiempo dedicado a los deberes; mientras que el rendimiento académico fue estimado en base a las notas en matemáticas y lengua ...

  11. Estudio de eficacia y coste en la electroestimulación medular como tratamiento de la angina refractaria Cost-effectiveness study of medullary electrostimulation for the management of refractory angina

    OpenAIRE

    Mayo, M.; Pallarés, J; C. Villalaín; A. Moreno-Gázquez; M. A. Canos; Almenar, L.

    2004-01-01

    Objetivo: Valorar la evolución de los pacientes, de nuestro hospital, diagnosticados de angina refractaria y tratada con estimulación eléctrica medular (EEM) cervical desde 1994-2002, además de valorar los costes asociados a dicho tratamiento y su relación coste/beneficio. Material y métodos: Estudio retrospectivo de 12 pacientes observando su evolución a lo largo de 8 años con controles clínicos periódicos, objetivándose tanto en la historia previa como posterior al implante, las siguientes ...

  12. Excimer laser coronary angioplasty: experience with a prototype multifibre catheter in patients with stable angina pectoris.

    Science.gov (United States)

    Kochs, M; Haerer, W; Eggeling, T; Hoeher, M; Schmidt, A; Hombach, V

    1992-03-01

    Percutaneous excimer laser coronary angioplasty (ELCA) was performed in a first group of 20 patients with stable angina pectoris caused by significant coronary stenosis, and long-term follow-up was evaluated. Prototype 4 to 5.5 French multifibre catheters with 18-20 quartz fibres of 100 microns diameter, concentrically arranged around a central lumen for taking up a guide wire, were coupled to a commercial XeCl excimer laser. Energy was delivered at a wavelength of 308 nm with a pulse duration of 60 or 120 ns. Operating at a repetition rate of 20 Hz, mean energy transmission was 13.4 +/- 6.8 mJ per pulse. In all but one patient the lesion could be passed by the catheter. Percent diameter stenosis decreased from 77.1 +/- 10.8% to 53.1 +/- 11.8% after ELCA. Complications were frequently observed, intracoronary thrombus formation in eight instances, dissection in six patients and spasm in five cases, causing total vessel occlusion in five procedures. All complications could be managed efficaciously by thrombolytic and vasodilating drugs and/or balloon angioplasty. Subsequent PTCA was performed in case of complication or insufficient stenosis reduction after ELCA in 18 patients with adequate results (residual stenosis, 28.5 +/- 10.2%). Long-term follow-up angiography, which could be performed in 16 of 19 laser treatments, demonstrated significant restenosis in only three patients. Our preliminary results suggest that, using ELCA, ablation of atherosclerotic lesions is feasible in most cases. However, compared with PTCA, stenosis reduction is significantly less, and the acute complication rate is much higher. Thus, further improvements of the catheter system are necessary in order to realize the advantages of excimer laser ablation, which can be demonstrated by experimental studies. PMID:1597220

  13. Effects of Salvia miltiorrhiza on Hemorheology and vascular endothelial function in patients with unstable angina pectoris

    Institute of Scientific and Technical Information of China (English)

    Shi-Lian Chen; Sheng-Bing Huang

    2016-01-01

    Objective:To investigate the effect of Salvia miltiorrhiza (SM) on vascular endothelial function and hemorheology in patients with unstable angina pectoris (UAP).Methods: A total of 60 cases of UAP patients from October 2014 to October 2015 as the research object, randomly divided into treatment group and control group; the two groups were treated with conventional bed rest, ECG monitoring, oxygen inhalation, application of nitroglycerin, beta blockers, aspirin and antiplatelet, statin therapy, the treatment group based on the use of salvianolate 200 mg+5% glucose 250 mL (neutralization amount of 0.9% sodium chloride was used in patients with diabetes or glucose insulin) intravenous drip, 1 times/d, two groups were treated for 2 weeks; the two groups before and after treatment and take venous blood in the morning fasting peripheral blood viscosity, plasma viscosity, measured by automatic blood rheometer (low and middle shear and high shear rate), hematocrit and erythrocyte aggregation index, serum endothelin (ET) and nitric oxide (NO) level was measured by nitrate reductase Set.Results:after the treatment, the treatment group, the plasma viscosity, whole blood viscosity (low shear, cut and high shear rate), red blood cell hematocrit and red blood cell aggregation index decreased than the control group, there is statistical significance; after treatment, in treatment group, the serum NO level, et reduce degree is significantly better than the contrast group, there is statistical significance.Conclusion: Salvia miltiorrhiza can effectively improve blood rheology, improve microcirculation, regulate vascular endothelial function, effectively reduce the risk of cardiovascular events in UAP patients, it is worthy of clinical application.

  14. CASE OF DIAGNOSIS OF APICAL FORM OF HYPERTROPHIC CARDIOMYOPATHY WITH A PATIENT WITH PROGRESSIVE ANGINA CLINIC

    Directory of Open Access Journals (Sweden)

    N. S. Krylova

    2014-01-01

    Full Text Available Objective of work: to describe the apical form of hypertrophic cardiomyopathy (AFHC developing under the "mask" of the ischemic heart disease not diagnosed for a long period.Materials and methods. Patient B., 73 y.o., female, was brought to the cardiology department with complains of severe pressing pain behind the breastbone caused with no apparent reason and lasting for over 4 hours. The following examination of the patient was performed: electrocardiography (ECG, echocardiography (EchoCG, Holter ECG monitoring, coronary angiography (CAG, ventriculography.Results. The final diagnosis for the patient was set on the basis of the following readings: ECG data (basic rhythm – atrial fibrillation, left ventricle (LV hypertrophy, negative T-waves in leads V1–6, ST segment depression up to 1–2 mm in leads V4–6, EchoCG (hypertrophy of apical segments of the LV with decreasing of its cavity, moderate dilatation of the left atrium, intraventricular obstruction in the apical third of the LV with the maximum pressure gradient of up to 48 mm Hg., CAG (stenotic lesions of coronary arteries were found, ventriculography (LV volume is not increased, no violations of local contractility, narrowing of the LV cavity in the lower third is observed with thinning in the apex, which indicatesexpressed apical hypertrophy of the LV myocard. AFHC, apical form with moderate obstruction in the lower third of the left ventricle. Stress angina syndrome. CAG and ventriculography were main diagnostic methods that allowed setting the final diagnosis.Conclusion. The clinical case sets forth the peculiarities of diagnostics, therapy, and post-therapy management of patients with this form of AFHC.

  15. CASE OF DIAGNOSIS OF APICAL FORM OF HYPERTROPHIC CARDIOMYOPATHY WITH A PATIENT WITH PROGRESSIVE ANGINA CLINIC

    Directory of Open Access Journals (Sweden)

    N. S. Krylova

    2015-01-01

    Full Text Available Objective of work: to describe the apical form of hypertrophic cardiomyopathy (AFHC developing under the "mask" of the ischemic heart disease not diagnosed for a long period.Materials and methods. Patient B., 73 y.o., female, was brought to the cardiology department with complains of severe pressing pain behind the breastbone caused with no apparent reason and lasting for over 4 hours. The following examination of the patient was performed: electrocardiography (ECG, echocardiography (EchoCG, Holter ECG monitoring, coronary angiography (CAG, ventriculography.Results. The final diagnosis for the patient was set on the basis of the following readings: ECG data (basic rhythm – atrial fibrillation, left ventricle (LV hypertrophy, negative T-waves in leads V1–6, ST segment depression up to 1–2 mm in leads V4–6, EchoCG (hypertrophy of apical segments of the LV with decreasing of its cavity, moderate dilatation of the left atrium, intraventricular obstruction in the apical third of the LV with the maximum pressure gradient of up to 48 mm Hg., CAG (stenotic lesions of coronary arteries were found, ventriculography (LV volume is not increased, no violations of local contractility, narrowing of the LV cavity in the lower third is observed with thinning in the apex, which indicatesexpressed apical hypertrophy of the LV myocard. AFHC, apical form with moderate obstruction in the lower third of the left ventricle. Stress angina syndrome. CAG and ventriculography were main diagnostic methods that allowed setting the final diagnosis.Conclusion. The clinical case sets forth the peculiarities of diagnostics, therapy, and post-therapy management of patients with this form of AFHC.

  16. Decreased soluble cell adhesion molecules after tirofiban infusion in patients with unstable angina pectoris

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    Aliyev Emil

    2004-04-01

    Full Text Available Abstract Aim The inflammatory response, initiated by neutrophil and monocyte adhesion to endothelial cells, is important in the pathogenesis of acute coronary syndromes. Platelets play an important role in inflammatory process by interacting with monocytes and neutrophils. In this study, we investigated the effect of tirofiban on the levels of cell adhesion molecules (soluble intercellular adhesion molecule-1, sICAM-1, and vascular cell adhesion molecule-1, sVCAM-1 in patients with unstable angina pectoris (AP. Methods Thirty-five patients with unstable AP (Group I, ten patients with stable AP (Group II and ten subjects who had angiographycally normal coronary arteries (Group III were included the study. Group I was divided into two subgroups for the specific treatment regimens: Group IA (n = 15 received tirofiban and Group IB (n = 20 did not. Blood samples for investigating the cell adhesion molecules were drawn at zero time (baseline; 0 h in all patients and at 72 h in Group I. Results The baseline levels of sICAM-1 and sVCAM-1 were higher in Group I than in Groups II and III. They were higher in Group IA than in Group IB. However, the sICAM-1 and sVCAM-1 levels decreased significantly in Group IA after tirofiban infusion. In contrast, these levels remained unchanged or were increased above the baseline value in Group IB at 72 h. Conclusion The levels of cell adhesion molecules in patients with unstable AP decreased significantly after tirofiban infusion. Inhibition of platelet function by specific glycoprotein IIb/IIIa antagonists may decrease platelet-mediated inflammation and the ischemic end-point.

  17. Decreased soluble cell adhesion molecules after tirofiban infusion in patients with unstable angina pectoris

    Science.gov (United States)

    Ercan, Ertugrul; Bozdemir, Huseyin; Tengiz, Istemihan; Sekuri, Cevad; Aliyev, Emil; Akilli, Azem; Akin, Mustafa

    2004-01-01

    Aim The inflammatory response, initiated by neutrophil and monocyte adhesion to endothelial cells, is important in the pathogenesis of acute coronary syndromes. Platelets play an important role in inflammatory process by interacting with monocytes and neutrophils. In this study, we investigated the effect of tirofiban on the levels of cell adhesion molecules (soluble intercellular adhesion molecule-1, sICAM-1, and vascular cell adhesion molecule-1, sVCAM-1) in patients with unstable angina pectoris (AP). Methods Thirty-five patients with unstable AP (Group I), ten patients with stable AP (Group II) and ten subjects who had angiographycally normal coronary arteries (Group III) were included the study. Group I was divided into two subgroups for the specific treatment regimens: Group IA (n = 15) received tirofiban and Group IB (n = 20) did not. Blood samples for investigating the cell adhesion molecules were drawn at zero time (baseline; 0 h) in all patients and at 72 h in Group I. Results The baseline levels of sICAM-1 and sVCAM-1 were higher in Group I than in Groups II and III. They were higher in Group IA than in Group IB. However, the sICAM-1 and sVCAM-1 levels decreased significantly in Group IA after tirofiban infusion. In contrast, these levels remained unchanged or were increased above the baseline value in Group IB at 72 h. Conclusion The levels of cell adhesion molecules in patients with unstable AP decreased significantly after tirofiban infusion. Inhibition of platelet function by specific glycoprotein IIb/IIIa antagonists may decrease platelet-mediated inflammation and the ischemic end-point. PMID:15059285

  18. Angina pectoris-like pain provoked by intravenous adenosine in healthy volunteers.

    Science.gov (United States)

    Sylvén, C; Beermann, B; Jonzon, B; Brandt, R

    1986-07-26

    In a study to characterise the chest pain induced by adenosine this agent was given as a bolus into a peripheral vein to six healthy volunteers (five men) aged 30-44. On the first day the maximum tolerable dose was determined in each case. On the second day three doses of adenosine (one third, two thirds, and the full maximum tolerable dose) and three doses of saline were given single blind in randomised order. Thereafter aminophylline 5 mg/kg was given and the procedure repeated in a different randomised order. On the third day between two thirds and the full maximum tolerable dose was given followed by 10 mg dipyridamole intravenously and a second injection of the same dose of adenosine. Heart rate and atrioventricular blocks were recorded by electrocardiography. One minute after each dose of adenosine the chest pain was scored. The maximum tolerable dose of adenosine ranged from 10.6 to 37.1 mg. All subjects experienced uneasy central chest pain provoking anxiety. The pain radiated to the shoulders, ulnar aspect of the arms, epigastric area, back, and into the throat. The pain began about 20 seconds after the injection and lasted 10-15 seconds. Increasing the dose of adenosine increased the intensity of the pain. Administration of aminophylline reduced the pain significantly. Second degree heart block was recorded in five of the six subjects during the time that the pain was experienced. After aminophylline no block was observed. Dipyridamole increased the intensity of pain. The duration of second degree heart block increased in four of the subjects, and in two of these third degree heart block occurred. These findings suggest that adenosine released from the myocardium during ischaemia induces angina pectoris by stimulating theophylline sensitive receptors. PMID:3089465

  19. Correlation between Timi Risk Score and Clinical Outcome in Patients with Unstable Angina Pectoris

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    Savovic Zorica

    2016-06-01

    Full Text Available Given Taking that the TIMI score is a major predictor of MACE, this study aimed to determine the value of the TIMI risk score in predicting poor outcomes (death, myocardial infarction, recurrent pain in patients presenting with unstable angina pectoris in short-term observation. A total of 107 patients with APns were examined at the Clinical Centre Kragujevac and were included in the investigation. The TIMI score was determined on the first day of hospitalization. During hospitalization, the following factors were also observed: troponin, ECG evolution, further therapy (pharmacologic therapy and/or emergency PCI or CABG, age, hypertension and hyperlipidaemia. The low-risk group (TIMI 0 - 2 included 30.8% of patients, whereas 47.6% of patients were in the intermediate-risk group (TIMI 3 - 4, and 21.5% of patients were in the high-risk group (TIMI 5 - 7. Good outcomes (without adverse event and poor outcomes (death, myocardial infarction, and recurring chest pain were dependent on the TIMI risk score. The increase in TIMI risk score per one unit increased the risk of a poor outcome by 54%. Troponin and TIMI risk score were positively correlated. Our results suggest that the TIMI risk score may be a reliable predictor of a poor outcome (MACE during the short-term observation of patients with APns. Moreover, patients identified as high-risk benefit from early invasive PCI, enoxaparin and Gp IIb/IIIa inhibitors. Th us, routine use of the TIMI risk score at admission may reduce the number of patients not recognized as high-risk.

  20. Unstable angina and non-ST-segment myocardial infarction: an evidence-based approach to management.

    Science.gov (United States)

    Kou, Victoria; Nassisi, Denise

    2006-01-01

    Unstable angina (UA) and non-ST-segment elevation myocardial infarction (NSTEMI) represent two common, closely related acute coronary syndromes with potentially high morbidity and mortality. Integration of information from the history, physical exam, electrocardiogram, and cardiac biomarkers is used to formulate both the diagnosis of UA/NSTEMI and the overall assessment of patient prognosis and risk. Early diagnosis and risk stratification of patients with UA/NSTEMI enable the physician to initiate timely, appropriate treatment. (There is strong clinical evidence supporting the tailoring of specific therapies to the risk profile of the patient.) In recent years, powerful new medical and invasive therapies have been developed. Pharmaceutical agents for UA/NSTEMI may be broadly grouped into one of three categories: anti-ischemic, anti-platelet, and anti-thrombotic agents. Standard therapy for UA/NSTEMI has commonly included oxygen, aspirin, nitrates, morphine, beta-blockers and heparin. Potent new anti-platelet agents, including inhibitors of platelet adenosine diphosphate and glycoprotein IIb/IIIa receptors, play important, expanding roles in the management of these syndromes. Low-molecular-weight heparins have been shown to be an effective alternative to unfractionated heparin in their treatment. Major advances in invasive techniques and devices over the last decade include revascularization with percutaneous coronary intervention and drug-eluting intracoronary stents. Strong interest exists in studying the potential benefits and risks associated with an early invasive therapeutic strategy rather than an aggressive medical regimen for patients with UA/NSTEMI. As new treatments are rapidly added to our growing arsenal of management options, clinicians are constantly challenged with incorporating complex new information and guidelines into their practices in a timely fashion. To assist clinicians with this challenge, this article will review the evidence to support

  1. Predictive factors of recurrent angina after acute coronary syndrome: the global registry acute coronary events from China (Sino-GRACE)

    Institute of Scientific and Technical Information of China (English)

    ZHAO Fu-hai; CHEN Yun-dai; SONG Xian-tao; PAN Wei-qi; JIN Ze-ning; YUAN Fei; LI Yong-bin; Ren Fang; L(U) Shu-zheng

    2008-01-01

    Background Many patients with acute coronary syndrome (ACS) develop recurrent angina (RA) during hospitalization. The aim of this non-randomized, prospective study was to investigate the predictive factors of RA in unselected patients with ACS enrolled in the global registry acute coronary events (GRACE) during hospitalization in China. Methods Between March 2001 and October 2004, enrolled were 1433 patients with ACS, including ST segment elevation myocardial infarction (662, 46.2%), non-ST segment elevation myocardial infarction (239, 16.7%) and unstable angina (532, 37.1%). The demographic distribution, medical history and clinical data were collected to investigate the predictive factors of RA by Logistic regression.Results During hospitalization 275 (19.2%) patients were documented with RA including unstable angina (53.2%), non-ST segment elevation myocardial infarction (27.5%), ST segment elevation myocardial infarction (19.3%). A comorbidity of dyslipidemia, prior angina, percutaneous coronary Intervention (PCI) within 6 months was more common in patients with RA, P<0.05. In the patients with RA, a significantly higher proportion of patients with acute pulmonary edema was observed, 23 (8.4%) versus 43 (3.7%), P=0.001. Acute renal failure was present in 8 (2.9%) of patients with RA versus 19 (1.6%) of patients without RA,P=0.165. Hemorrhagic events were present in 6 (2.2%) of patients with RA versus 8 (0.7%) of patients without RA, ventricular tachycardia/ ventricular fibrillation events in 12 patients (4.3%) versus 22 patients (1.9%), congestive heart failure in 69 patients (25.0%) versus 94 patients (8.1%), myocardial re-infarction in 28 patients (10.1%) versus 15 patients (1.3%), P<0.05, respectively. A lower proportion of patients with RA underwent in-hospital PCI, 687 (59.3%) versus 114 (41.5%), P=0.000. A higher proportion of patients with RA received heparin, 260 (94.5%) versus 1035 (89.4%), P=0.006; and beta-blockers 176(64.0%) versus 864 (74

  2. Exercise testing in patients with variant angina: results, correlation with clinical and angiographic features and prognostic significance

    International Nuclear Information System (INIS)

    Eighty-two patients with variant angina underwent a treadmill exercise test using 14 ECG leads, and 67 also underwent exercise thallium-201 scans. The test induced ST elevation in 25 patients (30%), ST depression in 21 (26%) and no ST-segment abnormality in 36 (44%). ST elevation during exercise occurred in the same ECG leads as during spontaneous attacks at rest, and was always associated with a large perfusion defect on the exercise thallium scan. In contrast, exercise-induced ST depression often did not occur in the leads that exhibited ST elevation during episodes at rest. The ST-segment response to exercise did not accurately predict coronary anatomy: Coronary stenoses greater than or equal to 70% were present in 14 of 25 patients (56%) with ST elevation, in 13 of 21 (62%) with ST depression and in 14 of 36 (39%) with no ST-segment abnormality (NS). However, the degree of disease activity did correlate with the result of the exercise test: ST elevation occurred during exercise in 11 of 14 patients who had an average of more than two spontaneous attacks per day, in 12 of 24 who had between two attacks per day and two per week, and in only two of 31 who had fewer than two attacks per week (p<0.005). ST elevation during exercise was reproducible in five of five patients retested during an active phase of their disease, but not in three of three patients who had been angina-free for a least 1 month before the repeat test. We conclude that in variant angina patients, the results of an exercise test correlate well with the degree of disease activity but not with coronary anatomy, and do not define a high-risk subgroup

  3. Influence of nifedipine on left ventricular perfusion and function in patients with unstable angina: Evaluation with radionuclide techniques

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    Wall, E.E. van der; Kerkkamp, H.J.; Simoons, M.L.; Rijk, P.P. van; Reiber, J.H.C.; Bom, N.; Lubsen, J.C.; Lie, K.I.

    1986-04-01

    In 1981, a large, double-blind, randomized trial was started in The Netherlands to evaluate the therapeutic effects of nifedipine and/or metoprolol in patients with unstable angina. This study has been called the Holland Interuniversity Nifedipine/metoprolol Trial (HINT) and required several hundred patients to establish potential therapeutic effects. From December 1982 to January 1984 the effects of nifedipine on left ventricular (LV) performance in a subgroup of 52 HINT patients were studied using radionuclide techniques. All patients (23 on nifedipine, 29 controls) underwent thallium-201 scintigraphy or radionuclide angiography just before and 48 h after the start of experimental medication. The radionuclide angiographic studies were also performed at 1 and 4 h after treatment. Nifedipine did not influence the incidence of disapperance of perfusion defects on the 48-h thallium images. No significant differences in overall LV ejections fraction (EF) were seen at any time between nifedipine-treated patients and controls. However, paired observations in 37 patients showed improvement of LVEF after 48 h in 8 patients on nifedipine and in only 1 control patient. Scintigraphic measurements on admission were not related to clinical outcome after 48 h. Concomitant administration of metoprolol did not influence LVEF in either group. It is concluded that nifedipine improves LVEF after 48 h in a subset of patients with unstable angina without affecting myocardial perfusion. This finding indicates that nifedipine has a predominant effect on afterload reduction in patients with unstable angina. Also, early scintigraphic measurements had no significant predictive value for subsequent cardiac events.

  4. Influence of nifedipine on left ventricular perfusion and function in patients with unstable angina: Evaluation with radionuclide techniques

    International Nuclear Information System (INIS)

    In 1981, a large, double-blind, randomized trial was started in The Netherlands to evaluate the therapeutic effects of nifedipine and/or metoprolol in patients with unstable angina. This study has been called the Holland Interuniversity Nifedipine/metoprolol Trial (HINT) and required several hundred patients to establish potential therapeutic effects. From December 1982 to January 1984 the effects of nifedipine on left ventricular (LV) performance in a subgroup of 52 HINT patients were studied using radionuclide techniques. All patients (23 on nifedipine, 29 controls) underwent thallium-201 scintigraphy or radionuclide angiography just before and 48 h after the start of experimental medication. The radionuclide angiographic studies were also performed at 1 and 4 h after treatment. Nifedipine did not influence the incidence of disapperance of perfusion defects on the 48-h thallium images. No significant differences in overall LV ejections fraction (EF) were seen at any time between nifedipine-treated patients and controls. However, paired observations in 37 patients showed improvement of LVEF after 48 h in 8 patients on nifedipine and in only 1 control patient. Scintigraphic measurements on admission were not related to clinical outcome after 48 h. Concomitant administration of metoprolol did not influence LVEF in either group. It is concluded that nifedipine improves LVEF after 48 h in a subset of patients with unstable angina without affecting myocardial perfusion. This finding indicates that nifedipine has a predominant effect on afterload reduction in patients with unstable angina. Also, early scintigraphic measurements had no significant predictive value for subsequent cardiac events. (orig.)

  5. Myocardial Strain Analysis by 2-Dimensional Speckle Tracking Echocardiography Improves Diagnostics of Coronary Artery Stenosis in Stable Angina Pectoris

    DEFF Research Database (Denmark)

    Biering-Sørensen, Tor; Hoffmann, Soren; Mogelvang, Rasmus;

    2014-01-01

    BACKGROUND: Two-dimensional strain echocardiography detects early signs of left ventricular dysfunction; however, it is unknown whether myocardial strain analysis at rest in patients with suspected stable angina pectoris predicts the presence of coronary artery disease (CAD). METHODS AND RESULTS......<0.001) and remained an independent predictor of CAD after multivariable adjustment for baseline data, exercise test, and conventional echocardiography (odds ratio, 1.25 [P=0.016] per 1% decrease). Area under receiver operating characteristic curve for exercise test and global longitudinal peak...

  6. Novel variant of dual left anterior descending artery arising from single right coronary artery anomaly presenting with angina inversa

    Science.gov (United States)

    Arslan, Gokhan; Iyisoy, Atilla; Bingol, Hakan

    2015-01-01

    A 55-year-old female without a history of coronary artery disease, hypertensive for the past 17 years, was admitted with resting chest pain. Electrocardiography revealed a negative T-wave in anterior chest leads. Coronary angiography visualised anomalous coronary anatomy, with a common origin of the right coronary artery and the left main coronary artery in the right sinus of Valsalva serving as a common coronary trunk. It should be emphasised that T-wave abnormalities and chest angina may be related to this congenital coronary anomaly. PMID:26702282

  7. Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina

    OpenAIRE

    Weverton Ferreira Leite; José Antonio Franchini Ramires; Luiz Felipe Pinho Moreira; Célia Maria Cassaro Strunz; José Armando Mangione

    2015-01-01

    Background: High sensitivity C-reactive protein (hs-CRP) is commonly used in clinical practice to assess cardiovascular risk. However, a correlation has not yet been established between the absolute levels of peripheral and central hs-CRP. Objective: To assess the correlation between serum hs-CRP levels (mg/L) in a peripheral vein in the left forearm (LFPV) with those in the coronary sinus (CS) of patients with coronary artery disease (CAD) and a diagnosis of stable angina (SA) or unstable an...

  8. Relevance of 123I-BMIPP delayed scintigraphic imaging for patients with angina pectoris – a pilot study

    OpenAIRE

    Koyama, Kohei; Akashi, Yoshihiro J.; Kida, Keisuke; Suzuki, Kengo; Ishibashi, Yuki; Musha, Haruki; Banach, Maciej

    2011-01-01

    Introduction The study was designed to clarify the role of 123I-β-methyl-iodophenylpentadecanoic acid (123I-BMIPP) in the evaluation of myocardial fatty acid metabolism in patients with stable angina pectoris (AP) before and after percutaneous coronary intervention (PCI). Material and methods Ten controls (mean age: 70.4 ±10.5 years) and 12 patients with AP (mean age: 67.4 ±11.6 years) and single vessel coronary artery disease participated in the radionuclide cardiac study. Scintigraphic imag...

  9. Prinzmetal's variant angina evolved in inferior myocardial infarction with involvement of the right ventricle: Sequential radionuclide evaluation

    International Nuclear Information System (INIS)

    A patient with Prinzmetal's variant angina (PVA) who developed an inferolateral myocardial infarction with right-ventricle involvement was studied using sequential radionuclide imaging until 5 months after the acute event. The patient also underwent-contrast ventriculography and coronary-artery angiography. Equilibrium-gated radionuclide angiography (EGRA) revealed the localization of ventricular dysfunction, the results obtained being in agreement with haemodynamic data. We emphasize the usefulness of the parameters obtained using EGRA (regional wall motion, systolic and diastolic parameters) in planing therapy and follow-up. (orig.)

  10. FEATURES OF CYTOKINE PRODUCTION IN PATIENTS WITH UNSTABLE ANGINA: DEPENDENCE ON ETHNICITY IN THE REPUBLIC OF SAKHA (YAKUTIA)

    OpenAIRE

    A. S. Golderova; I. N. Nikolaeva; V. E. Tarasova; V. A. Kozlov

    2014-01-01

    Abstract. We investigated levels of spontaneous and mitogen-induced cytokine production (IL-1β, IL-4, IL-6, IL-10 and IFNγ) by peripheral blood cells of 24 men with unstable angina (UA), including indigenous population (n = 12, Yakuts), and a group of Russian migrants to the Republic of Sakha (n = 12). Activation of inflammatory response was revealed in the total group of patients with UA, manifesting by increase of spontaneous and induced production of the pro-inflammatory IL-1β, IL-6 cytoki...

  11. Ranolazine for the symptomatic treatment of patients with chronic angina pectoris in Greece: a cost-utility study

    OpenAIRE

    Kourlaba, Georgia; Vlachopoulos, Charalambos; Parissis, John; Kanakakis, John; Gourzoulidis, George; Maniadakis, Nikos

    2015-01-01

    Background To conduct an economic evaluation comparing ranolazine as add-on therapy to standard-of-care (SoC) with SoC alone in patients with stable angina who did not respond adequately to first line therapy, in Greece. Methods A decision tree model was locally adapted in the Greek setting to evaluate the cost-utility of ranolazine during a 6-month period. The analysis was conducted from a third-party payer perspective. The clinical inputs were extracted from the published literature. The co...

  12. Are negative aspects of social relations predictive of angina pectoris? A 6-year follow-up study of middle-aged Danish women and men

    DEFF Research Database (Denmark)

    Lund, Rikke; Rod, Naja Hulvej; Christensen, Ulla

    2011-01-01

    after adjustment for age, gender, social class, cohabitation status and depression in a dose-response manner. For example, experiencing excessive demands or worries always/often from different roles in the social relations was associated with an increased risk: partner OR=3.53 (1.68 to 7.43), children...... OR=2.19 (1.04 to 4.61), other family OR=1.91 (1.24 to 2.96). Except for frequent conflicts with the partner and neighbours, conflicts with the social relations was not a risk factor for angina. The authors found no interaction of negative aspects of social relations with gender, age, social class......, cohabitation status or depression in terms of angina. Conclusion Excessive demands and serious worries from significant others seem to be important risk factors for development of angina pectoris....

  13. La escala de reajuste social para niños de primaria en México

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    Ana Marina Reyes Sandoval

    2008-01-01

    Full Text Available Los eventos vitales pueden tener efectos nocivos sobre la salud. La Escala de Reajuste Social es uno de los instrumentos más utilizados para medir estrés vital. Éste se ha cuantificado mediante juicios sobre la magnitud del reajuste necesario ante cada evento. Al promedio de los puntajes se le conoce como Unidad de Cambio de Vida (LCU, por sus siglas en inglés. El propósito de este estudio fue obtener una versión en español del SRRS para niños de primaria y obtener los puntajes LCU. 192 maestros de escuelas primarias actuaron como jueces. Correlaciones por rangos mostraron un alto grado de acuerdo tanto entre los maestros, como respecto a los jueces estadounidenses del estudio original de Coddington (1972 en relación con la severidad de los eventos. Comparaciones por pares mostraron que los maestros en función de sus características sociodemográficas, juzgaron ciertos eventos como más severos

  14. Las representaciones sociales sobre Derechos Humanos en niños de primaria

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    Germán Flores Martínez

    2015-08-01

    Full Text Available La presente investigación tuvo como objetivo principal la exploración y descripción de las representaciones sociales que los niños de educación primaria de quinto grado manifiestan sobre los Derechos Humanos. El estudio, realizado desde un enfoque cualitativo, se llevó a cabo en la Escuela Primaria Rural Emiliano Zapata, de la comunidad de Xochiteotla, Chiutempan, Tlaxcala (México. La población del estudio está conformada por 26 alumnos entre los 11 y 12 años. Los resultados obtenidos demuestran que los niños tienen una visión de los Derechos Humanos construida desde su contexto, y materializada en personas que cumplen con una función social. También los derechos humanos se materializan en objetos y en situaciones de su realidad; tanto en su lenguaje, como en su representación gráfica.

  15. materiales educativos de enseñanza primaria: atavismos y horizontes

    Directory of Open Access Journals (Sweden)

    Ileana Schmidt Díaz de León

    2003-01-01

    Full Text Available Los materiales educativos han sido considerados por los investigadores medios de socialización, especialmente los libros de texto de educación primaria. Este trabajo analiza, desde una perspectiva de género, los papeles sociales y la estructura de poder de la sociedad mexicana enseñada a los niños mexicanos a través de materiales educativos. Éstos incluyen manuales para el maestro y libros de texto gratuitos de primero y segundo grados de educación primaria escritos en español y en lengua náhuatl para la Huasteca y la Sierra Norte de Puebla, así como algunos de los libros usados como complementarios para estos grados en las escuelas privadas. De los libros de texto gratuitos en español, se han analizado y comparado los editados antes del Programa para la Modernización Educativa (1989-1994 y los elaborados y publicados a partir de 1992 como producto del mismo programa. Debido a que el contenido básico de los libros de primero y segundo grados son el individuo y la familia, se prefirió analizar fundamentalmente éstos, aunque en algunas ocasiones se incluyen materiales de otros grados para apoyar los argumentos presentados.

  16. Procedimiento para la gestión ambiental en la escuela primaria

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    Migdely Barbarita Ochoa-Ávila

    2011-01-01

    Full Text Available Abordó resultados alcanzados con la investigación doctoral "Modelo y procedimiento de gestión ambiental para la escuela primaria" desarrollada desde el año 2006 hasta el presente, mediante la aplicación del procedimiento para la gestión ambiental en una muestra de escuelas primarias del municipio de Holguín, lo que tributa a la calidad del medio ambiente no solo en escuelas sino en el medio ambiente local. El procedimiento consta de cinco etapas y veinte pasos, este introduce un elemento dinamizador de integración entre las escuelas y el sector empresarial. Los resultados más significativos fueron, la realización de diagnósticos ambientales, la conformación de planes de acción para la realización de capacitaciones y encuentros técnicos, lo que enriquece la visión en aras delmejoramiento continuo del medio ambiente escolar. Se cuenta con certificados de protección por CENDA, avales de la comisión científica del CIGET y de la Dirección Municipal de Educación, varios premios y publicaciones.

  17. Paquidermoperiostosis (osteoartropatía hipertrófica primaria Pachydermoperiostosis (primary hypertrophic osteoarthropathy

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    Javier A. Cavallasca

    2006-04-01

    Full Text Available La paquidermoperiostosis u osteoartropatía hipertrófica primaria es una rara enfermedad caracterizada por compromiso cutáneo y osteoarticular. Comunicamos dos casos que presentaban hipocratismo digital, uñas en vidrio de reloj, agrandamiento óseo, tumefacción articular y diferentes grados de afectación cutánea, sin otros hallazgos clínicos relevantes. Ambos desconocían antecedentes familiares similares. El estudio radiográfico de las zonas comprometidas mostró periostosis. Con resultados de laboratorio y radiografía de tórax normales, y ausencia de evidencia clínica de otra enfermedad subyacente, se realizó diagnóstico de osteoartropatía hipertrófica primaria.Pachydermoperiostosis or primary hypertrophic osteoarthropathy is a rare disease characterized by cutaneous and osteo-arthicular involvement. We describe two patients with finger clubbing, watch crystal nails, bones thickenings, arthritis and different grades of skin affection, without other clinical manifestations. Both did not know of having relatives with the same alterations. Radiological studies of the affected areas showed periostosis. Because of normal laboratory results and chest radiography plus the absence of other underlying causes, diagnosis of primary hypertrophic osteoarthropathy was made.

  18. Historia del tratamiento de las vasculitis primarias History of treatment of primary vasculitis

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    Antonio Iglesias-Gamarra

    2012-07-01

    Full Text Available Las vasculitis primarias constituyen un grupo de enfermedades reumáticas con expresión clínica variable y pronóstico reservado cuando no se tratan adecuadamente. En esta revisión haremos un análisis pormenorizado del tratamiento en las diferentes formas de vasculitis primaria, iniciando con el uso de los corticoides, desde casi su descubrimiento en 1949, pasando por otros inmunosupresores como: ciclofosfamida, metotrexate, azatioprina, mofetil, micofenolato, al igual que medicamentos biológicos como rituximab y anti-TNF. Una mención especial se hace sobre las guías de tratamientos para las vasculitis, tanto de grandes como de pequeños vasos, implementadas desde 2009 por el Grupo Europeo de Estudio de las Vasculitis.Primary vasculitis is one of the rheumatic diseases with variable clinical expression and poor prognosis when not treated properly. In this review we analyze detailed treatment of this disease in different forms of primary vasculitis, starting with the use of corticosteroids from almost its discovery in 1949, to other immunosuppressant's such as cyclophosphamide, methotrexate, azathioprine, mycophenolate mofetil, as well as biological drugs such as rituximab and anti-TNF. Special mention is made on the guidelines of treatment for vasculitis of both large and small vessel, implemented since 2009 by the European Group Study of Vasculitis.

  19. Las primeras manifestaciones artísticas como recurso en educación primaria: Las pinturas de Altamira

    OpenAIRE

    Trejo Malfaz, María Jesús

    2014-01-01

    Propuesta para el aula con el objetivo de acercar el arte rupestre, más concretamente el arte parietal, a los niños/as de educación primaria. Para conseguir este objetivo recurriremos a las pinturas de la cueva de Altamira.

  20. Aprendiendo a enseñar mediante el Modelo de Educación Deportiva (Sport Education Model). Experiencia inicial en Educación Primaria

    OpenAIRE

    Antonio Calderón Luquin; Peter A. Hastie; Diego Martínez de Ojeda Pérez

    2010-01-01

    En este trabajo se pretende analizar la experiencia inicial de aplicación de un profesor y de sus alumnos en el contexto de la educación primaria, con objeto de comprobar si son coincidentes los resultados encontrados en la literatura de la ED, en un país no angloparlante como España y en las condiciones concretas de este trabajo (educación primaria, y habilidades no específicas de deporte). La unidad de análisis se compuso por una clase de 48 alumnos de tercer curso de primaria (29 chicos y ...

  1. Impacto de una intervención informativa sobre el programa de cribado de cáncer colorrectal en profesionales de atención primaria

    OpenAIRE

    Benito-Aracil, Llúcia; Binefa, Gemma; Milà, Núria; Lluch Canut, Ma. Teresa; Puig Llobet, Montserrat; García Martínez, Montserrat

    2015-01-01

    Objetivo: Evaluar el impacto de una intervención informativa a profesionales de atención pri-maria sobre sus conocimientos de cribado de cáncer colorrectal, recomendaciones de vigilanciaposterior y estrategias de derivación. Método diseÑo: Ensayo clínico controlado y aleatorizado por conglomerados. Emplazamiento:centros de atención primaria de L'Hospitalet de Llobregat (Barcelona). Participantes: médi-cos y enfermeras de atención primaria. Intervención: sesión informativa y envío de píldorasi...

  2. Cribado para el trastorno bipolar en pacientes de atención primaria que presentan síntomas psicológicos

    OpenAIRE

    Enric Aragonès; Juan A. López-Rodríguez; Francisco Escobar-Rabadán; Juan Téllez-Lapeira; José Mínguez; Ignacio Párraga; Tatiana Suárez-Hernández; María José Piñero; Marta-Magdalena Guzón

    2015-01-01

    Objetivo: Estimar la proporción de resultados positivos en el cribado del trastorno bipolar (TB) entre los pacientes de atención primaria que consultan por problemas de naturaleza psicológica, y analizar sus características. Diseño: Estudio descriptivo transversal multicéntrico. Emplazamiento: Diecinueve consultas de atención primaria en diferentes comunidades autónomas. Pacientes: La muestra estuvo formada por 360 pacientes consecutivos de atención primaria con edades entre 18 y 70 ...

  3. Recursos de internet y su aplicación en la enseñanza de la Geometría en Primaria

    OpenAIRE

    Lobo de Frutos, Francisco Javier

    2015-01-01

    En este documento se analiza el currículum LOMCE de Matemáticas en lo referente al estudio de la geometría en Primaria. Se aportan los fundamentos psicopedagógicos que aconsejan la utilización de los múltiples recursos que ofrece Internet para la enseñanza de la geometría en Primaria. Se describe la realidad en lo relativo al uso de las TIC en los centros docentes de Primaria en España para la enseñanza de la geometría. Asimismo, se detallan las dificultades que encuentran los docentes par...

  4. GAMMAGRAFÍA DE PERFUSIÓN MIOCÁRDICA EN MUJERES POSMENOPÁUSICAS CON ANGINA Y CORONARIAS EPICÁRDICAS ANGIOGRÁFICAMENTE NORMALES / Myocardial perfusion scintigraphy in postmenopausal women with angina and angiographically normal epicardial coronary

    Directory of Open Access Journals (Sweden)

    Sherien Sixto Fernández

    2011-03-01

    Full Text Available Introduction and Objectives: Microvascular angina is common in postmenopausal women. Myocardial ischemia was induced by stress testing, and reports have been published about the relationship between endothelial dysfunction and myocardial perfusion. The objective of this research was to determine whether myocardial ischemia can be evidenced by abnormalities in perfusion and function, as detected by myocardial scintigraphy in women with typical angina, normal coronary angiography and endothelial dysfunction. Methods: 59 women underwent lipid and endothelial function measurements by brachial artery ultrasound, in addition, a 24-hour ECG study (Holter. During the scintigraphy a stress-rest protocol was applied. Patients were divided into two groups according to presence (group I or absence (group II of myocardial perfusion defects. Results: 21 patients showed perfusion defects. 57 % of group I exhibited greater endothelial dysfunction. Only twelve patients showed reversible perfusion defects, and 75 % of the cases was associated with a reduction of post-stress left ventricular ejection fraction, greater than 5 %, and regional abnormalities of wall motion. Three patients in group I showed evidence of ischemia compared with four in Group II. Conclusions: The stress-induced ischemia was associated with a reduced post-stress ejection fraction and endothelial dysfunction in the studied women, and no ischemic changes in the Holter were found.

  5. Estudio de eficacia y coste en la electroestimulación medular como tratamiento de la angina refractaria Cost-effectiveness study of medullary electrostimulation for the management of refractory angina

    Directory of Open Access Journals (Sweden)

    M. Mayo

    2004-07-01

    Full Text Available Objetivo: Valorar la evolución de los pacientes, de nuestro hospital, diagnosticados de angina refractaria y tratada con estimulación eléctrica medular (EEM cervical desde 1994-2002, además de valorar los costes asociados a dicho tratamiento y su relación coste/beneficio. Material y métodos: Estudio retrospectivo de 12 pacientes observando su evolución a lo largo de 8 años con controles clínicos periódicos, objetivándose tanto en la historia previa como posterior al implante, las siguientes variables: fracción de eyección del ventrículo izquierdo (FEVI, estadio funcional NYHA, frecuencia de ingresos hospitalarios, frecuencia de episodios anginosos e ingesta de cafinitrinas, sensación subjetiva de mejora del dolor anginoso, exitus, costes hospitalarios previos y posteriores a la colocación del EEM. Resultados: El electrodo de EEM fue implantado a nivel cervical siendo más frecuente la localización C2-C3 (58,3%. No se presentó ninguna complicación intraoperatoria. En el postoperatorio inmediato tuvimos como única complicación un desplazamiento del electrodo. No hubo ninguna complicación a largo plazo. Comprobamos que existió una disminución del número de anginas por semana (14 vs 4 p = 0,005 asociada a una disminución del número de tomas de nitroglicerina de acción rápida (15,7 vs 3,8 p = 0,002 y a una disminución en el número de ingresos hospitalarios/año (2,62 vs 0,84 p = 0,003. La mejoría subjetiva por parte del paciente tras la colocación del neuroestimulador fue del 70%. En cuanto al coste hospitalario quinquenal (conformado sólo por el coste del ingreso sin pruebas complementarias fue de 37.921,85 e en los pacientes con angina refractaria que no portaban EEM, frente a los 15.150,25 € de los pacientes portadores EEM.Objective: To assess the evolution of patients in our hospital with diagnosis of refractory angina treated with cervical medul-lary electrostimulation (MES over the period 1994-2002, and to

  6. Plasma α1-antitrypsin: A Neglected Predictor of Angiographic Severity in Patients with Stable Angina Pectoris

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    Hui Zhao

    2015-01-01

    Full Text Available Background: As an acute phase protein, α1-antitrypsin (AAT has been extensively studied in acute coronary syndrome, but it is unclear whether a relationship exists between AAT and stable angina pectoris (SAP. The purpose of the present study was to investigate the association between AAT plasma levels and SAP. Methods: Overall, 103 SAP patients diagnosed by coronary angiography and clinical manifestations and 118 control subjects matched for age and gender were enrolled in this case-control study. Plasma levels of AAT, high-sensitivity C-reactive protein (hsCRP, lipid profiles and other clinical parameters were assayed for all participants. The severity of coronary lesions was evaluated based on the Gensini score (GS assessed by coronary angiography. Results: Positively correlated with the GS (r = 0.564, P < 0.001, the plasma AAT level in the SAP group was significantly higher than that in the control group (142.08 ± 19.61 mg/dl vs. 125.50 ± 19.67 mg/dl, P < 0.001. The plasma AAT level was an independent predictor for both SAP (odds ratio [OR] = 1.037, 95% confidence interval [CI]: 1.020-1.054, P < 0.001 and a high GS (OR = 1.087, 95% CI: 1.051-1.124, P < 0.001 in a multivariate logistic regression model. In the receiver operating characteristic curve analysis, plasma AAT level was found to have a larger area under the curve (AUC for predicting a high GS (AUC = 0.858, 95% CI: 0.788-0.929, P < 0.001 than that of hsCRP (AUC = 0.665, 95% CI: 0.557-0.773, P = 0.006; Z = 2.9363, P < 0.001, with an optimal cut-off value of 137.85 mg/dl (sensitivity: 94.3%, specificity: 68.2%. Conclusions: Plasma AAT levels correlate with both the presence and severity of coronary stenosis in patients with SAP, suggesting that it could be a potential predictive marker of severe stenosis in SAP patients.

  7. [Exercise tolerance in angina patients 3 and 24 hours after administration of a new delayed-action preparation of metoprolol].

    Science.gov (United States)

    Giusti, C; Verdecchia, P; Pentimone, F; Regoli, F; Cordoni, M; Bongini, A M

    1981-01-01

    To assess the duration of improved exercise tolerance by metoprolol given in a new sustained-release formulation, 40 in-patients affected by stable exercise-induced angina pectoris received single-blind placebo in day 1 and thereafter, in double-blind cross-over once daily administration, metoprolol RETARD 100 mg and 200 mg in days 3 and 5. Symptom-limited cycloergometric exercise tests were performed at 3 and 24 hours after placebo and after each of the two doses of metoprolol RETARD. Duration of exercise, maximal workload and total work performed did significantly increase at 3 and 24 hours after metoprolol RETARD 100 mg (P less than 0.01) and 200 mg (P less than 0.01), without any significant difference between the two doses. Peak systolic arterial pressure and heart rate were lowered by metoprolol RETARD 200 mg at 3 (P less than 0.01) and 24 (P less than 0.01) hours, whereas only the peak heart rate at 3 hours was lowered (P less than 0.05) by the 100 mg dose. It is concluded that in patients with stable exercise-induced angina pectoris, metoprolol RETARD 200 mg appears to be able to increase exercise tolerance and to reduce exercise-induced myocardial oxygen consumption throughout 24 hours period. This may justify a once daily dosing schedule of the 200 mg dose, aimed at improving patient compliance. PMID:7343379

  8. Behavior of right and left ventricles during episodes of variant angina in relation to the site of coronary vasospasm

    International Nuclear Information System (INIS)

    The effects of single-vessel coronary occlusion on simultaneously evaluated right (RV) and left ventricular (LV) performance were assessed and compared with LV perfusion patterns in 25 patients with variant angina. Coronary spasm involved the right coronary artery in 15 patients (group 1) and the left anterior descending coronary artery in 10 patients (group 2). Biventricular function was assessed by radionuclide angiography under basal conditions, during spontaneous or ergonovine-induced ischemia, and after resolution of the ischemic attack. Myocardial perfusion was assessed by thallium 201 scintigraphy in 21 patients of this series during superimposable ischemic episodes. In group 1, ischemia caused RV (14 of 15 patients) and LV (13 of 15 patients) regional dysfunction with significant reduction in RV and LV ejection fractions. The interventricular spetum was involved in six of 15 patients, causing a more pronounced LV impairment. In group 2, all patients showed septal dyssynergies associated with a reduction of LV ejection fraction; absent or trivial RV involvement was observed. In both groups, LV perfusion defects were present in all patients with LV wall motion abnormalities during ischemia, matching the site of regional dyssynergies. Thus, in a group of patients with variant angina and single-vessel disease, transient occlusion of the right coronary artery directly caused RV and LV impairment; in these patients, the extent of LV but not RV dysfunction appeared related to the presence of septal ischemia. Vasospasm of the left anterior descending coronary artery consistently caused LV dysfunction not associated with secondary effects on RV systolic function

  9. Effects of XUEZHIKANG on Oxidized Low Density Lipoprotein,C- Reactive Protein, Fibrinogen in Unstable Angina Pectoris Patients

    Institute of Scientific and Technical Information of China (English)

    姚青海; 崔长琮; 王军奎; 姚晓伟

    2003-01-01

    Objectives To study the effects of XUEZHIKANG on lipid modulating and thelevel of oxidized low density lipoprotein (OX - LDL),C -reactive protein(CRP), fibrinogen(FIB) in serum.Methods XUEZHIKANG was given to patientswith unstable angina pectoris and hyperlipidemia at adose of 0.6 gram bid for 2 months and with half-dose for another 2 months. Vitamin E was given tounstable angina pectoris patients with normal lipid atthe dose of 0.1 gram bid for 4 months respectively.Then compared the level of lipid and OX - LDfL, CRP,FIB in serum at beginning, first -month and second -month. Results XUEZHIKANG can reduce theserum level of total cholesterol, low density lipoproteinin 1 month , and gained better effect in 2 months. Itcan also reduce triglyceride and increase high densitylipoprotein in 2 months. Compared with vitamin EXUEZHIKANG can reduce the level of OX- LDL,CRP, FIB significantly after treatment for 2 months.Conclusions XUEZHIKANG has significant effectin lipid modulating , and it can also inhibit the de-velopment of inflammation in coronary plaque.

  10. Evaluation of plaque texture by means of multislice computed tomography in patients with acute coronary syndrome and stable angina

    International Nuclear Information System (INIS)

    In the present study, multislice spiral computed tomography (MSCT), which allows non-invasive assessment of coronary artery plaque, was used to compare the CT density of plaque between patients with acute coronary syndrome (ACS) and those with stable angina (SA). MSCT was performed in 20 patients with ACS (17 with acute myocardial infarction, 3 with unstable angina) and 22 patients with SA. The presence of the plaque was defined on the basis of multi-planar reformation and axial images. At least 4 regions of interest were then placed within the plaque and the minimum CT density was measured and expressed as Hounsfield units (HU). The number of plaques did not differ between the 2 groups, but the minimum CT density was significantly lower in patients with ACS (25±15 HU) than in those with SA (71±16 HU, range 46-101 HU, p<0.001). Similarly, the minimum plaque density was significantly lower in the culprit coronary segment (26±16 HU) than in the non-culprit segment (48±17 HU) in 15 ACS patients with multiple plaques. MSCT can potentially differentiate vulnerable from stable plaque in patients with coronary artery disease, although long-term, prospective analysis is needed to establish the conclusion. (author)

  11. Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina

    Energy Technology Data Exchange (ETDEWEB)

    Leite, Weverton Ferreira, E-mail: wfleite@cardiol.br [Instituto do Coração (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP (Brazil); Hospital Beneficência Portuguesa de São Paulo, São Paulo, SP (Brazil); Ramires, José Antonio Franchini; Moreira, Luiz Felipe Pinho; Strunz, Célia Maria Cassaro [Instituto do Coração (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP (Brazil); Mangione, José Armando [Hospital Beneficência Portuguesa de São Paulo, São Paulo, SP (Brazil)

    2015-03-15

    High sensitivity C-reactive protein (hs-CRP) is commonly used in clinical practice to assess cardiovascular risk. However, a correlation has not yet been established between the absolute levels of peripheral and central hs-CRP. To assess the correlation between serum hs-CRP levels (mg/L) in a peripheral vein in the left forearm (LFPV) with those in the coronary sinus (CS) of patients with coronary artery disease (CAD) and a diagnosis of stable angina (SA) or unstable angina (UA). This observational, descriptive, and cross-sectional study was conducted at the Instituto do Coração, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, and at the Hospital Beneficência Portuguesa de Sao Paulo, where CAD patients referred to the hospital for coronary angiography were evaluated. Forty patients with CAD (20 with SA and 20 with UA) were included in the study. Blood samples from LFPV and CS were collected before coronary angiography. Furthermore, analysis of the correlation between serum levels of hs-CRP in LFPV versus CS showed a strong linear correlation for both SA (r = 0.993, p < 0.001) and UA (r = 0.976, p < 0.001) and for the entire sample (r = 0.985, p < 0.001). Our data suggest a strong linear correlation between hs-CRP levels in LFPV versus CS in patients with SA and UA.

  12. Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina

    Directory of Open Access Journals (Sweden)

    Weverton Ferreira Leite

    2015-03-01

    Full Text Available Background: High sensitivity C-reactive protein (hs-CRP is commonly used in clinical practice to assess cardiovascular risk. However, a correlation has not yet been established between the absolute levels of peripheral and central hs-CRP. Objective: To assess the correlation between serum hs-CRP levels (mg/L in a peripheral vein in the left forearm (LFPV with those in the coronary sinus (CS of patients with coronary artery disease (CAD and a diagnosis of stable angina (SA or unstable angina (UA. Methods: This observational, descriptive, and cross-sectional study was conducted at the Instituto do Coração, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, and at the Hospital Beneficência Portuguesa de Sao Paulo, where CAD patients referred to the hospital for coronary angiography were evaluated. Results: Forty patients with CAD (20 with SA and 20 with UA were included in the study. Blood samples from LFPV and CS were collected before coronary angiography. Furthermore, analysis of the correlation between serum levels of hs-CRP in LFPV versus CS showed a strong linear correlation for both SA (r = 0.993, p < 0.001 and UA (r = 0.976, p < 0.001 and for the entire sample (r = 0.985, p < 0.001. Conclusion: Our data suggest a strong linear correlation between hs-CRP levels in LFPV versus CS in patients with SA and UA.

  13. Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina

    International Nuclear Information System (INIS)

    High sensitivity C-reactive protein (hs-CRP) is commonly used in clinical practice to assess cardiovascular risk. However, a correlation has not yet been established between the absolute levels of peripheral and central hs-CRP. To assess the correlation between serum hs-CRP levels (mg/L) in a peripheral vein in the left forearm (LFPV) with those in the coronary sinus (CS) of patients with coronary artery disease (CAD) and a diagnosis of stable angina (SA) or unstable angina (UA). This observational, descriptive, and cross-sectional study was conducted at the Instituto do Coração, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, and at the Hospital Beneficência Portuguesa de Sao Paulo, where CAD patients referred to the hospital for coronary angiography were evaluated. Forty patients with CAD (20 with SA and 20 with UA) were included in the study. Blood samples from LFPV and CS were collected before coronary angiography. Furthermore, analysis of the correlation between serum levels of hs-CRP in LFPV versus CS showed a strong linear correlation for both SA (r = 0.993, p < 0.001) and UA (r = 0.976, p < 0.001) and for the entire sample (r = 0.985, p < 0.001). Our data suggest a strong linear correlation between hs-CRP levels in LFPV versus CS in patients with SA and UA

  14. Effect of the platelet membrane GP Ⅰ a gene polymorphism in the pathogenesis of unstable angina pectoris

    Institute of Scientific and Technical Information of China (English)

    Yonghui Zhao; Changcong Cui; Yanni Wang; Jiaqing Zhu

    2005-01-01

    Objective: To investigate the effect of platelet membrane glycoprotein(GP) Ⅰ a gene polymorphism in the pathogenesis of unstable angina pectoris (UAP) in Chinese people. Methods: Collagen type Ⅰ -induced platelet aggregation was measured in 33healthy subjects in vitro. Plasma level of α-granule membrane protein (GMP-140) was measured in both the above 33 healthy subjects during fasting and 35 patients with recent onset effort anina during rest onset within 24 h after hospitalization. Furthermore, the platelet membrane GP Ⅰ a gene 807C/T polymorphism was checked in all subjects with polymerase chain reaction-sequence specific primers(PCR-SSP)technique. Results: The lag time before 30% platelet aggregation was significantly longer in healthy subjects with CC genotype than with TC genotype ( P <0.01). However, there was no significant difference in the maximal platelet aggregation between healthy subjects with the above two genotypes. Plasma level of GMP-140 was significantly higher in TC genotypic patients with recent onset effort angina than in CC genotypic patients with the same type of UAP( P < 0.05) and healthy subjects ( P < 0.01), furthermore, there was also significant difference between the latter two groups( P < 0.05). Conclusion: The rapid initiation of collagen-induced platelet aggregation may be associated with platelet membrane GP Ⅰ a T807 allele, which may play an important role in the pathogenesis of UAP.

  15. The Impact of Remote Ischemic Preconditioning on Arterial Stiffness and Heart Rate Variability in Patients with Angina Pectoris.

    Science.gov (United States)

    Zagidullin, Naufal; Scherbakova, Elena; Safina, Yuliana; Zulkarneev, Rustem; Zagidullin, Shamil

    2016-01-01

    Remote ischemic preconditioning (RIPC) is the set of ischemia episodes that protects against subsequent periods of prolonged ischemia through the cascade of adaptive responses; however, the mechanisms of RIPC are not entirely clear. Here, we aimed to study the impact of RIPC in patients with stable angina pectoris and compare it with healthy individuals with respect to arterial stiffness and heart rate variability. In the randomized, sham-controlled, crossover blind design study, a group of 30 coronary heart disease (CHD) patients (63.9 ± 1.6 years) with stable angina pectoris NYHA II-III and a control group of 20 healthy individuals (58.2 ± 2.49) were both randomly allocated for remote RIPC or sham RIPC. Arterial stiffness, pulse wave velocity (Spygmacor, Australia), and heart rate variability (HRV) were recorded before and after the procedure followed by the crossover examination. In the group of healthy individuals, RIPC showed virtually no impact on the cardiovascular parameters, while, in the CHD group, the systolic and central systolic blood pressure, central pulse pressure, and augmentation decreased, and total power of HRV improved. We conclude that ischemic preconditioning reduces not only systolic blood pressure, but also reduces central systolic blood pressure and improves arterial compliance and heart rate modulation reserve, which may be associated with the antianginal effect of preconditioning. PMID:27348009

  16. The effects of lidoflazine on exercise performance and thallium stress scintigraphy in patients with stable angina pectoris

    International Nuclear Information System (INIS)

    Lidoflazine is a synthetic drug with calcium-channel blocking effects. In a 7-month study, 36 patients with stable angina pectoris were tested during a 3-month single-blind placebo phase. Nineteen were then randomized by double-blind methods to lidoflazine and 17 to placebo therapy. The lidoflazine group had a significant (p < 0.01) reduction in anginal attacks; the placebo group did not. Exercise testing demonstrated that lidoflazine therapy was associated with a 34% increase in total work performance and a 15.6% increase in peak calculated oxygen uptake during double-blind treatment (both p < 0.004 compared with the placebo group). Heart rate was significantly reduced at submaximal levels of exercise during lidoflazine therapy (p < 0.04). Nitroglycerin consumption and electrocardiographic changes at the end of exercise did not change during the double-blind phase. In a second study of six similar patients, single-blind administration of lidoflazine was associated with improved myocardial perfusion during exercise as determined by thallium-201 stress scintigraphy. These studies demonstrate that lidoflazine therapy is associated with relief of angina, an increased physical work capacity, and improved regional myocardial perfusion during exercise

  17. Angina pré-infarto na evolução intra-hospitalar de pacientes idosos com infarto agudo do miocárdio Preinfarction angina and in-hospital outcome of elderly patients with acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Chiu Wen Shian

    2007-12-01

    Full Text Available FUNDAMENTO: A angina pré-infarto (API pode ser um marcador de pré-condicionamento isquêmico. Foi demonstrada redução da área infartada, do remodelamento ventricular, da incidência de insuficiência cardíaca, choque cardiogênico ou morte, quando a API estava presente. Esses resultados foram mais evidentes em adultos, porém, não em idosos. OBJETIVO: Avaliar a relação entre API e a evolução clínica de pacientes idosos com infarto agudo do miocárdio (IAM. MÉTODOS: Estudo tipo série de casos com grupo de comparação. Foram incluídos 36 pacientes com diagnóstico de IAM com elevação do segmento ST. Os pacientes foram distribuídos em grupo A (21 pacientes com API e grupo B (15 pacientes sem API. RESULTADOS: A idade média da população estudada foi 70,5 anos. A maioria (73% dos pacientes era do sexo masculino. O índice de massa corpórea médio foi 25,3 kg/m2. A amostra era constituída por 77,8% de hipertensos, 27,8% de diabéticos e 32,4% de dislipidêmicos. Dor torácica tipo A foi relatada por 71,4% dos estudados. A maioria (72,2% dos idosos foi classificada em Killip I. Os desfechos clínicos nos grupos A e B foram: angina pós-infarto 9,5% versus 20%, p=0,630; insuficiência cardíaca 23,8% versus 13,3%, p=0,674; revascularização de urgência 4,8% versus 6,7%, p=1; arritmia cardíaca 0% versus 6,7%, p=0,417. Não foi constatado nenhum caso de reinfarto, choque cardiogênico e morte até 30 dias em ambos os grupos. CONCLUSÃO: A presença da angina pré-infarto não se associou com uma melhor evolução clínica em idosos acometidos por IAM nesta série de casos.BACKGROUND: Preinfarction angina (PIA may be a marker of ischemic preconditioning. A decrease in infarct size, ventricular remodeling, congestive heart failure, cardiogenic shock or death was demonstrated in the presence of preinfarction angina. These findings were more evident in adults, but not in the elderly. OBJECTIVE: To assess the relationship between PIA

  18. Detección y prevalencia del trastorno por uso de alcohol en los centros de atención primaria de Cataluña

    Directory of Open Access Journals (Sweden)

    Laia Miquel

    2016-03-01

    Conclusiones: Los MAP reconocen poco el TUA en gente joven, mientras que detectan más la enfermedad en pacientes de mayor edad y con comorbilidades asociadas. La prevalencia de TUA es elevada en atención primaria.

  19. Actividades físicas en el medio natural. La orientación con bicicleta en el tercer ciclo de educación primaria

    OpenAIRE

    Rincón Rodrigo, Santos

    2016-01-01

    El trabajo es un plan de intervención de desarrollo de una jornada de orientación llevada a cabo de una forma novedosa, es decir, con la bicicleta, destinada para niños del tercer ciclo de E. Primaria. El trabajo consta de una sesión en la zona de Boca del Asno (Valsaín). Grado en Educación Primaria

  20. Sequential comparison of therapy with beta-blockers and calcium channel blockers with celiprolol therapy in patients with angina pectoris, hypertension, or both

    NARCIS (Netherlands)

    Cleophas, TJM; Niemeyer, MG; Bernink, PJLM; Zwinderman, KH; Wijk, AV; Wall, EEVD

    1996-01-01

    Unlike patients with either hypertension (HT) of angina pectoris (AP) alone, patients with both HT and AP usually have a reduced left ventricular compliance and may, therefore, have an impaired capability to cope with acute hemodynamic changes generated by standard beta-blockers or calcium channel b

  1. Increased expression and plasma levels of myeloperoxidase are closely related to the presence of angiographically-detected complex lesion morphology in unstable angina

    NARCIS (Netherlands)

    T. Naruko; A. Furukawa; K. Yunoki; R. Komatsu; M. Nakagawa; Y. Matsumura; N. Shirai; K. Sugioka; M. Takagi; T. Hozumi; A. Itoh; K. Haze; M. Yoshiyama; A.E. Becker; M. Ueda

    2010-01-01

    Background Myeloperoxidase (MPO) is a leucocyte enzyme that catalyses the formation of a number of reactive oxidant species. Objective The purpose of this study is to evaluate the relationship between angiographic coronary plaque morphology in patients with unstable angina pectoris (UAP) or stable a

  2. Incidence and impact on prognosis of peri-procedural myocardial infarction in 2760 elective patients with stable angina pectoris in a historical prospective follow-up study

    DEFF Research Database (Denmark)

    Christensen, Martin Kirk; Huang, Hui; Torp-Pedersen, Christian;

    2016-01-01

    elevated biomarkers after elective PCI in patients with stable angina pectoris using the defined cut-off (>5 x URL) was 15.2 % using cTnT and 4.1 % using CK-MBmass. The independent prognostic value for both cardiac biomarkers of any cut-off showed no statistical significance for all-cause mortality...

  3. Role of multi-slice CT coronary angiography in evaluating the different patterns of coronary artery disease in patients with unstable angina

    Directory of Open Access Journals (Sweden)

    Gamal Eldine M. Niazi

    2015-09-01

    Conclusion: Non-invasive multi-slice CT coronary angiography is a reliable technique of high ability to detect coronary artery disease and estimate the degree of obstruction, number of affected arteries and the pattern of their affection and can be used in workup in patients with unstable angina.

  4. Construcción del autoconcepto en alumnos/as de 6º de primaria

    OpenAIRE

    Galindo Martínez, Silvia

    2013-01-01

    El estudio del auto-concepto continúa siendo uno de los grandes retos de la investigación psicológica. En la construcción del auto-concepto suelen tenerse en cuenta diferentes dimensiones tales como la dimensión académica, social, emocional, familiar y física. Hoy en día, el auto-concepto académico se considera una variable fundamental en el rendimiento escolar. En el trabajo empírico he aplicado cuestionarios sobre el auto-concepto a alumnos/as de 6º de primaria (11-12 años) y la profesora d...

  5. El BLOG: PENSAMIENTO DE LOS PROFESORES EN FORMACIÓN EN EDUCACIÓN PRIMARIA

    Directory of Open Access Journals (Sweden)

    Verónica MARÍN DÍAZ

    2016-01-01

    Full Text Available La inclusión de los blog en las aulas supone la modi¿cación de las metodologías didácticas de los docentes. La necesidad de que los estudiantes de educación primaria consigan al ¿nalizar los estudios la competencia informacional y digital supone que los blogs puedan formar parte de la ecología curricular. La investigación llevada a cabo con maestros en formación inicial tiene como objetivo saber si los blogs pueden ser una herramienta para el desarrollo del currículo. A través de un cuestionario conformado por 40 ítems, se ha obtenido, como principal resultado, su gran utilidad, fundamentalmente para los docentes con dos años de formación.

  6. La multimorbilidad vista desde la perspectiva de los profesionales de atención primaria

    Directory of Open Access Journals (Sweden)

    Roberto Nuño-Solinís

    2014-06-01

    Conclusiones: El aumento de la multimorbilidad es una realidad que preocupa a los profesionales de atención primaria. Los profesionales manifiestan la necesidad de disponer formación adecuada y de sistemas de ayuda a la decisión y de soporte de la práctica diaria que contemplen las situaciones y combinaciones de multimorbilidad más frecuentes. Un abordaje más efectivo de esta problemática requiere un cambio en el modelo sanitario que privilegie una visión integral del paciente, la transición de un enfoque paternalista a uno más proactivo y el desarrollo de la integración asistencial.

  7. El lenguaje audiovisual como medio de expresión artística en Primaria

    OpenAIRE

    Sancerni, María Mercedes

    2012-01-01

    El origen de este proyecto es el interés y la fascinación personal por el mundo de las imágenes y por las posibilidades pedagógicas que puede ofrecer su conocimiento, dominio y reflexión en nuestros estudiantes. Centrándonos más concretamente en este estudio, en los alumnos/as de Sexto de Primaria. Para lograrlo realizaremos una investigación de carácter teórico-práctico centrada en el lenguaje cinematográfico y las características esenciales de los conceptos que lo conforman: tipos de plano,...

  8. Aplicación del método Binding en 1º de Primaria

    OpenAIRE

    Campos-Pardo, Mercedes

    2016-01-01

    El presente trabajo profundiza en el Método Binding y diseña un proyecto educativo para aplicarlo este método en un aula de 1º de Primaria. Binding es un método innovador, apoyado en una base científica, para aprender a leer y para mejorar la comprensión lectora de los alumnos. Utiliza la metodología RTI y pretende que ningún niño se quede atrás en la lectura. Se estudian las dificultades lectoras y de comprensión lectora para detectar los problemas lo antes posible. El proyecto educativo es ...

  9. Una propuesa didáctica con materiales manipulativos para la educación primaria

    OpenAIRE

    Martín, Sagrario

    2012-01-01

    Este artículo trata sobre una experiencia del área de Matemáticas en segundo ciclo de primaria. El objetivo es enseñar y aprender los contenidos de dicha área partiendo de la manipulación de materiales específicos, como juegos, figuras para geometría, fichas para la numeración, relojes de papel… que hemos creado y llevado al aula en el curso escolar 2010/11. La principal conclusión es que los niños se han sentido enormemente motivados en la presentación de los contenidos, que han adquirido de...

  10. La oncología en la atención primaria de salud

    OpenAIRE

    Mendoza del Pino, Mario Valentín

    2009-01-01

    El Libro “La Oncología en la Atención Primaria de Salud”, constituye un importante aporte para la prevención y atención del cáncer, desde una valoración muy integral. Se trata de una enfermedad que constituye la segunda causa de muerte en nuestro país, que tanto dolor y sufrimiento representa para el paciente y sus familiares. El libro tiene un enfoque muy útil para el Equipo Básico de Salud, ya que enfatiza que el cáncer puede prevenirse si logramos en la población cambios en el estilo de v...

  11. TIC en primaria: Finale en el aula de música

    OpenAIRE

    Razkin-Aguirre, Amaia

    2014-01-01

    En el presente Trabajo Fin de Grado se lleva a cabo el diseño de una propuesta didáctica, tomando en cuenta las características de un colegio de primaria con un Proyecto de Música Integrado. La principal característica de la propuesta es la inclusión del software Finale a lo largo de las diferentes unidades didácticas, diseñadas desde una perspectiva que aúna las líneas generales en las que se basan los métodos activos de música. Por tanto, el objetivo del proyecto ha sido fusionar el uso de ...

  12. Diabetes mellitus: Manejo en la atención primaria de salud

    Directory of Open Access Journals (Sweden)

    Rubén Darío García Múñez

    2010-12-01

    Full Text Available Se realizó una revisión de las principales guías para el diagnóstico, seguimiento y control de la diabetes mellitus. Específicamente se abordan las principales evidencias relacionadas con estos aspectos de la mencionada entidad para el contexto particular de la atención primaria de salud, así como la interrelación con otras especialidades y niveles de atención, para ofrecer un servicio de calidad a los pacientes diabéticos.A review on the main guidelines for the diagnosis, monitoring and control of diabetes mellitus was conducted. Evidences related to the diagnosis, monitoring and treatment of this disease in the primary health care were also reviewed, as well as interactions with other medical specialties in order to provide a quality service to these patients.

  13. Cardiopatía isquémica. Atención primaria de salud

    Directory of Open Access Journals (Sweden)

    Luís Padrón Velázquez

    2010-12-01

    Full Text Available En el siguiente artículo se realiza una revisión de las evidencias actuales relacionadas con la conducta a seguir ante un paciente aquejado de una enfermedad cardiovascular, y en especial de una cardiopatía isquémica. Se presentan los criterios para el diagnóstico y tratamiento de las principales formas de cardiopatía isquémica en la atención primaria de salud, así como el manejo del infarto agudo de miocardio.This article presents a review on the current evidence related to the procedures to be followed when dealing with patients suffering from cardiovascular disease and particularly ischemic heart disease. We present the criteria for the diagnosis and treatment of major forms of heart disease in primary health care and the management of miocardial infarction.

  14. La agilidad en alumnos de educación primaria: diferencias por edad y sexo

    OpenAIRE

    Yanci, J; Los Arcos, A.; R. Reina; Gil, E.; Grande, I.

    2014-01-01

    Se evaluó la agilidad en 110 niños (63 chicos y 47 chicas) divididos en dos grupos de alumnos de educación primaria: (a) Grupo 1 (G1) (n=53): alumnos de 1º curso (6.3±0.6 años), y (2) Grupo 2 (G2) (n=57): alumnos de 4º curso (9.5±0.4 años). Se utilizó una modificación respecto al MAT (28) para la valoración de la agilidad: el MAT2. Los propósitos del estudio fueron cuantificar el nivel de agilidad de los dos grupos, comprobar la influencia de las variables edad y sexo en la agilidad en edades...

  15. Escalas de evaluación de riesgo suicida en atención primaria

    Directory of Open Access Journals (Sweden)

    Claudia Ximena Rangel-Garzón

    2015-10-01

    Full Text Available Antecedentes. El médico de atención primaria debe decidir qué hacer con un paciente que ha atentado contra su vida o manifiesta ideación suicida. Posiblemente puede interconsultar a psiquiatría; sin embargo, ocasionalmente esto se difiere. Objetivo. Encontrar un instrumento de evaluación del riesgo suicida en adultos que pueda ser aplicado por el médico general en el servicio de urgencias. Materiales y métodos. Revisión de la literatura en PubMed con los términos MeSH: ‘suicide', ‘risk assessment' y ‘scales'; se encontraron 270 artículos a los que se les analizaron los abstract y finalmente se incluyeron 24 estudios. Resultados. Se encontraron nueve instrumentos y se descartaron los demás por involucrar diagnóstico específico, grupos de edad distintos, poblaciones específicas diferentes, tiempo prolongado de aplicación y otros determinantes enfocados en los factores protectores y en opiniones del paciente acerca del suicidio. Conclusiones. Estas escalas se pueden usar como instrumento de ayuda para definir una conducta en un paciente con riesgo suicida, pero no reemplazan la entrevista psiquiátrica. Se postulan las escalas Modified Scale for Suicide Ideation y Plutchik Suicide Risk Scale por cumplir con las características psicométricas, por tener un tiempo de aplicación adecuado en el servicio de urgencias y por sus preguntas sencillas para ser utilizadas en atención primaria.

  16. IL PROCESSO DI PRODUZIONE SCRITTA: LA COESIONE VERBALE IN TESTI DI SCUOLA PRIMARIA

    Directory of Open Access Journals (Sweden)

    Fabiana Rosi

    2015-02-01

    Full Text Available Una delle principali difficoltà che incontrano i bambini della scuola primaria nella produzione scritta riguarda la coesione verbale, ovvero il mantenimento lungo il testo della dimensione temporale inizialmente selezionata per riportare gli eventi. L’articolo esamina questo specifico tipo di competenza testuale negli alunni di sei classi del secondo ciclo della scuola primaria, tre delle quali hanno partecipato alla sperimentazione educativa sulla produzione di testi scritti “Osservare l’interlingua”. Il confronto fra i dati raccolti all’inizio e alla fine dell’anno scolastico mostra una riduzione dei salti immotivati da un tempo verbale all’altro, definiti shift temporali, nei testi prodotti nelle classi del campione sperimentale in misura maggiore rispetto a quelle di controllo e sottolinea gli effetti positivi, a breve e lungo termine, di una didattica task-based condotta con approccio inclusivo, cooperativo ed attivo.  The process of writing: verb cohesion in primary school textsOne of principal difficulties in producing written texts for primary school pupils concerns verb cohesion, i.e. maintaining the temporal dimension initially chosen for expressing events throughout the text. The paper examines this specific textual competence in pupils from six classes within second cycle of primary school. Three of these classes were involved in the “Observing interlanguage” project focused on written production. The comparison of data collected at the beginning and the end of school year shows a decrease in temporal shifts (transitions from one verb tense to another in the texts produced by the students involved in the project with regard to the control group. These findings highlight the positive effects, both short-term and long-term, of task-based teaching through an inclusive, cooperative and active approach. 

  17. Conocimientos tecnológicos, pedagógicos y disciplinares del profesorado de Primaria

    Directory of Open Access Journals (Sweden)

    Rosabel Roig Villa

    2015-07-01

    Full Text Available La emergencia de las tecnologías de información y comunicación (TIC plantea nuevos desafíos educativos al profesorado, a los cuales puede responder desde un modelo de formación coherente. El propósito de este estudio es analizar los conocimientos tecnológicos, pedagógicos y disciplinares del profesorado de Educación Primaria, necesarios para la integración de las TIC en la labor docente. Para ello, se llevó a cabo una investigación con una metodología cuantitativa de carácter no experimental en la que participaron 224 profesores de Educación Infantil y Primaria de la provincia de Alicante. Los resultados mostraron que los docentes poseen mayores conocimientos pedagógicos y disciplinares que tecnológicos, lo que conlleva a escasos conocimientos para la integración de las TIC en la labor docente. Se constataron, además, diferencias significativas entre el género y los años de experiencia docente, y la relación entre el uso lúdico de la tecnología y los conocimientos sobre sus aspectos fundamentales. Según los resultados obtenidos, se corrobora la necesidad de una alfabetización digital del profesorado abordada no solo desde una formación tecnológica, sino también pedagógica y disciplinar de forma global. Ello responde al modelo TPACK (Technological, Pedagogical and Content Knowledge, el cual se contempla como un marco de referencia a tener en cuenta por lo que respecta al desarrollo profesional del profesorado y su vinculación a los procesos de enseñanza-aprendizaje en el aula donde las TIC estén presentes.

  18. Hipertensión arterial pulmonar primaria o idiopática

    Directory of Open Access Journals (Sweden)

    Yazmín Ravelo-Calzado

    2010-01-01

    Full Text Available La hipertensión arterial pulmonar primaria (HAPP es una enfermedad crónica de causa desconocida que se caracteriza por un incremento de la presión sanguínea media en la arteria pulmonar, mayor de 25 mmHg en reposo o más de 30 mmHg durante el ejercicio. Es una enfermedad que afecta a ambos sexos y no tiene predilección racial. La HAPP sin tratar puede conducir a una insuficiencia ventricular derecha y por consiguiente, a la muerte. La HAPP involucra varios mecanismos subyacentes, dentro de los cuales la vasoconstricción, el remodelado vascular y la trombosis in situ son los más importantes. Aunque hasta el presente la HAPP no tiene cura, se ha logrado mejorar la calidad de vida de los pacientes utilizando diversas estrategias terapéuticas, tanto farmacológicas como quirúrgicas. Por tanto, el conocimiento de los factores que predisponen al desarrollo de la HAPP, así como la búsqueda de alternativas para su tratamiento o una cura definitiva es de interés actual. El presente trabajo describe brevemente las características de la HAPP incluyendo datos de la epidemiología, fisiopatología, manifestaciones clínicas, causas y factores de riesgo. Además, describe las principales terapias farmacológicas empleadas en los pacientes con HAPP, así como algunos modelos experimentales que permiten evaluar nuevos fármacos potencialmente efectivos para tratar la hipertensión arterial pulmonar primaria.

  19. Apendagitis epiploica primaria: Clínica y evolución de 73 casos

    Directory of Open Access Journals (Sweden)

    Graciela M Vázquez

    2014-12-01

    Full Text Available La apendagitis epiploica primaria es una enfermedad relativamente infrecuente dentro de los diagnósticos diferenciales del abdomen agudo. Describimos las características clínicas y evolución de una serie de 73 casos de apendagitis epiploica primaria. Se realizó una búsqueda de imágenes ecográficas y tomográficas con diagnóstico de apendagitis en el sistema de información hospitalario electrónico del Hospital Alemán entre abril del 2007 y julio del 2013 y posteriormente se revisaron sus historias clínicas. Se incluyeron 73 casos; la edad promedio fue de 45 años (± 16, 54 (74% eran varones. El motivo de consulta fue dolor abdominal: en fosa ilíaca izquierda en 65 (el 89% de los casos; en fosa ilíaca derecha en seis (8% y en otras localizaciones en dos (3%. Se les realizó ecografía abdominal a 44 (60%, tomografía computarizada a 21 (29%, y ambos estudios a 8 (11%. En el 49% de los casos se solicitó interconsulta con el servicio de cirugía. Recibieron tratamiento con antibióticos 15 (21% pacientes, de los cuales el 73% fue indicado por un médico clínico. Recibieron tratamiento ambulatorio con antiinflamatorios no esteroides 67 (92%; dos requirieron cirugía laparoscópica, dos internación y dos opiáceos. La apendagitis epiploica es infrecuente dentro de los diagnósticos diferenciales de abdomen agudo, pero es una entidad que no debe ser desconocida por los médicos para prevenir intervenciones innecesarias y el uso excesivo de antibióticos.

  20. Angina pré-infarto na evolução intra-hospitalar de pacientes idosos com infarto agudo do miocárdio Preinfarction angina and in-hospital outcome of elderly patients with acute myocardial infarction

    OpenAIRE

    Chiu Wen Shian; Sandro Gonçalves de Lima; Brivaldo Markman Filho

    2007-01-01

    FUNDAMENTO: A angina pré-infarto (API) pode ser um marcador de pré-condicionamento isquêmico. Foi demonstrada redução da área infartada, do remodelamento ventricular, da incidência de insuficiência cardíaca, choque cardiogênico ou morte, quando a API estava presente. Esses resultados foram mais evidentes em adultos, porém, não em idosos. OBJETIVO: Avaliar a relação entre API e a evolução clínica de pacientes idosos com infarto agudo do miocárdio (IAM). MÉTODOS: Estudo tipo série de casos com ...

  1. A controlled comparison of oxyfedrine, isosorbide dinitrate and placebo in the treatment of patients suffering attacks of angina pectoris.

    Science.gov (United States)

    Whittington, J; Raftery, E B

    1980-09-01

    1 In a group of 23 patients with documented ischaemic heart disease who experienced angina pectoris, oral oxyfedrine (24 mg three times daily) was compared with isosorbide dinitrate (10 mg three times daily) and placebo in a double-blind double-crossover clinical trial. 2 Isosorbide dinitrate appeared no better than placebo, either in terms of symptomatic relief or ECG responses to exercise. Thirty eight per cent of patients complained of headaches and 28% had to cease taking the drug for this reason. 3 Oxyfedrine produced statistically significant improvements in both symptom level (P exercise (P effect noted was a reversible loss of taste sensation by one patient. 4 Neither drug produced any adverse changes in any haematological or biochemical parameters. 5 Oxyfedrine is, therefore, to be preferred to isosorbide dinitrate, being both much better tolerated and more efficacious. PMID:7002181

  2. Cardiac rehabilitation: a good measure to improve quality of life in peri- and postmenopausal women with microvascular angina

    Directory of Open Access Journals (Sweden)

    Wojciech Szot

    2015-05-01

    Full Text Available Cardiac Syndrome X (CSX was considered a stable coronary syndrome, yet due to its nature, CSX symptoms often have a great impact on patients’ Quality of Life (QoL. According to ESC 2013 stable coronary artery disease criteria, CSX was replaced by Microvascular Angina (MA.Unfortunately, most CSX or MA patients, after classical angina (involving main coronary vessels has been ruled out, often do not receive proper treatment. Indications for pharmacological treatment of MA patients were introduced only recently. Another problematic issue is that scientists describing the pathophysiology of both CSX and MA stress a lack of a deeper insight into the multifactorial etiology of the source of pain associated with this disease. In the presented article we have attempted to study the influence of cardiac rehabilitation (3 months programme on the QoL of patients recognized as suffering from MA, as well as to check if changes in myocardial perfusion in these patients at baseline and after completion of cardiac rehabilitation match changes in their QoL. Therefore, after screening 436 women for MA, we studied 55 of them who were confirmed as having MA and who agreed to participate in the study. Exercise tests, Myocardial Perfusion Imaging, and QoL questionnaires were studied at baseline and after completing 3 months period of cardiac rehabilitation. Results were subsequently compared, which showed a link between improved perfusion score in SPECT study and improved overall physical capacity, on one hand, and improved QoL score on the other. These results confirm that cardiac rehabilitation is a very useful treatment option for MA patients. It seems that training during cardiac rehabilitation is a very important factor (improved physical efficiency –> increase in self-belief, and that taking into consideration the multifactor pathophysiology of pain, it is connected with a better quality of life for MA patients.

  3. A literature review to evaluate the economic value of ranolazine for the symptomatic treatment of chronic angina pectoris.

    Science.gov (United States)

    Vellopoulou, Katerina; Kourlaba, Georgia; Maniadakis, Nikos; Vardas, Panagiotis

    2016-05-15

    To conduct a systematic review of the evidence regarding the economic value of ranolazine relative to standard-of-care (SOC) for the treatment of symptomatic chronic stable angina (CSA). Electronic databases were searched using relevant keywords. The identified studies were independently reviewed by two investigators against pre-determined inclusion and exclusion criteria. Their data were extracted using a relevant form and consequently were synthesized. Studies were also evaluated using the Quality of Health Economic Studies scale. The main outcomes considered were the cost and effectiveness for each comparator and the incremental cost per quality-adjusted-life year (QALY) gained. Six studies were included in the review. Five of these assessed the cost-utility of ranolazine added to SOC, compared to SOC alone, using decision trees or Markov models whereas one was a retrospective cost evaluation study. The analysis was conducted from a payer perspective in five studies and from a societal perspective in one study with the time horizon varying between six months and a year. The incremental cost-effectiveness ratio (ICER), ranged from €4000 to €15,000 per QALY gained. Ranolazine appears to be dominant or cost-effective, mainly due to its ability to decrease angina-related hospitalizations and also due to a marginal improvement in quality of life. The acquisition cost of ranolazine was the variable with the greatest impact upon the ICER. The existing evidence, although limited, indicates that ranolazine may be a dominant or cost-effective therapy option, for the treatment of patients with symptomatic CSA. Further research is required to evaluate the cost-effectiveness of ranolazine. PMID:26994453

  4. Patterns of disturbed myocardial perfusion in patients with coronary artery disease. Regional myocardial perfusion in angina pectoris

    International Nuclear Information System (INIS)

    Fifty patients who presented with angina pectoris were studied to examine the disturbances of regional myocardial perfusion during stress. Each patient underwent 16-point precordial mapping of the ECG during an exercise test, and coronary and left ventricular angiography. Regional myocardial perfusion was assessed using an atrial pacing test and a short-lived radionuclide, krypton-81m. Eleven patients had negative exercise tests and uniform increases in myocardial activity of krypton-81m of 98 +/- 18.0% during pacing. Ten patients performed 30,000-43,000 J in positive exercise tests. These patients showed abnormal coronary anatomy and increases in myocardial activity of krypton-81m to remote and jeopardized myocardium at the onset of pacing. However, further pacing produced a decrease in activity in the affected segment of 68.0 +/- 9.0% accompanied by ST-segment depression and angina. Twelve patients achieved 26,000-32,000 J in positive exercise tests and had significant coronary artery disease. Atrial pacing produced increased activity of krypton-81m to remote myocardium. The jeopardized segment at first showed no change and then a decrease in regional activity of krypton-81m (89.0 +/- 17%) accompanied by ST-segment depression and chest pain. Seventeen patients achieved only 7000-22,000 J in positive exercise tests. These patients showed abnormal coronary anatomy and developed decreases in regional activity of krypton-81m to the affected segment of myocardium starting at the onset of atrial pacing and decreasing by 88 +/- 0 7.0% below control. We conclude that different patterns of disturbed myocardial distribution of krypton-81m are present during stress-induced ischemia in patients with coronary artery disease. There was a close temporal relationship between these disturbances and ST-segment depression

  5. Evaluation of pharmacokinetics and pharmacodynamics relationships for Salvianolic Acid B micro-porous osmotic pump pellets in angina pectoris rabbit

    Directory of Open Access Journals (Sweden)

    Shu-Ling Kan

    2014-06-01

    Full Text Available The work aims to investigate the in vitro release, pharmacokinetics (PK, pharmacodynamics (PD and PK–PD relationships of Salvianolic Acid B micro-porous osmotic pump pellets (SalB-MPOPs in angina pectoris New Zealand White (NZW rabbits, compared with those of SalB immediate-release pellets (SalB-IRPs. The SalB plasma concentrations and Superoxide dismutase levels (PD index were recorded continuously at predetermined time interval after administration, and the related parameters were calculated by using WinNonlin software. The release profile of MPOPs was more sustained than that of IRPs. PK results indicated that the mean Cmax was significantly lower, the SalB plasma concentrations were steadier, both area under concentration-time curve from 0 to 24 h (AUC0–24 h and from 0 to infinity (AUC0–∞ were presented larger, and both the peak concentration time (Tmax and mean residence time (MRT were prolonged for MPOPs, as compared with those of IRPs. PD results suggested that peak drug effect (Emax was lower and the equilibration rate constant (ke0 between the central compartment and the effect compartment was higher of MPOPs vs. those of IRPs. PK–PD relationships demonstrated that the effect-concentration-time (ECT course of MPOPs was clockwise hysteresis loop, and that of IRPs was counter-clockwise hysteresis loop. Collectively, those results demonstrated that MPOPs were potential formulations in treating angina pectoris induced by atherosclerosis.

  6. Estudio de las dimensiones del lenguaje en un alumno con TDAH de Educación Primaria.

    OpenAIRE

    Hernández-Castro, Leyla

    2012-01-01

    Objetivos: Se pretende analizar las dimensiones del lenguaje (fonético-fonológica, morfológica, sintáctica, semántica y pragmática) en un niño de Educación Primaria con TDAH y comparar los resultados con una muestra de niños normales. Material y Método: Se aplica a un niño de 6º de Primaria, el Registro Fonológico Inducido y el BLOC: Batería de Lenguaje Objetiva y Criterial para detectar las áreas deficitarias de cada una de las dimensiones del lenguaje. Resultados: Se han obtenido peor...

  7. La didáctica de la Historia del Arte en la Educación primaria

    OpenAIRE

    García-Martí, Gemma

    2013-01-01

    El presente trabajo se centra en el arte y su historia dentro de la educación primaria como una materia importante en el despertar de los más pequeños en relación con el mundo que les rodea. El estudio se estructura en dos partes claramente diferenciadas. La primera se presenta como un estado de la cuestión a través del cual se describe la situación actual de la didáctica de la historia del arte en la Educación primaria. La presencia de la materia en el currículo escolar, su inclu...

  8. CONDICIONANTES DEL RENDIMIENTO ACADÉMICO EN LA ESCOLARIDAD PRIMARIA EN BRASIL: UN ANÁLISIS MULTIFACTORIAL

    Directory of Open Access Journals (Sweden)

    Mauro Mediavilla

    2016-03-01

    Full Text Available RESUMEN: Una problemática educativa actual en Brasil es el alto porcentaje de alumnos en la escolaridad primaria que muestran un bajo nivel académico. Esta situación justifica el análisis de los determinantes del rendimiento académico en matemáticas para la totalidad de alumnos y su comparación al colectivo con un rendimiento considerado insuficiente. Para ello, se emplea una aproximación lineal y multivariante a partir de los datos contenidos en la base de datos del Sistema de Avaliação da Educação Básica 2005. En conjunto, los resultados obtenidos permiten afirmar que las dimensiones asociadas a la educabilidad resultan determinantes para comprender los rendimientos observados en la educación primaria.

  9. Diagnóstico del ojo rojo para el médico de atención primaria

    Directory of Open Access Journals (Sweden)

    Virgilio Galvis Ramírez

    2008-12-01

    Full Text Available El ojo rojo es uno de los motivos de consulta más comunes en atención ocular primaria, y el médico no oftalmólogo tiene la vital función de discernir cuando se trata de una patología que pueda amenazar la visión. En este artículo revisamos el enfoque diagnóstico del ojo rojo de acuerdo a nuestra experiencia profesional y empleando Medline para localizar artículos sobre el tema. Adicionalmente sugerimos un flujograma que esperamos guíe al médico de atención primaria al enfrentarse a estos casos.

  10. La enseñanza de la lengua inglesa en el aula de Educación Primaria

    OpenAIRE

    Soria Calvo, Estela Eva

    2014-01-01

    El objetivo de este trabajo es la realización de una experiencia de práctica docente en un aula de primer curso de Educación Primaria, centrada en el área de Science. Haremos un estudio sobre la enseñanza del inglés como Segunda Lengua dentro del aula de Educación Primaria y su evolución hasta llegar a la enseñanza del inglés dentro del bilingüismo. Analizaremos el uso de Tecnologías de la Información y la Comunicación y la importancia de su uso en el aula de Educación Prima...

  11. Las TIC y la enseñanza del inglés en el aula de Primaria

    OpenAIRE

    Santa Cruz Molinero, Patricia

    2014-01-01

    Este trabajo tiene como objetivo evaluar el uso de las Tecnologías de la Información y de la Comunicación en Educación Primaria y en concreto, en la enseñanza de una Lengua Extranjera, en un área no lingüística como es Science. De esta manera se hará una aproximación teórica sobre las teorías de la enseñanza de una lengua extranjera y del uso de las TIC en el aula de Primaria y seguidamente se hará un estudio de caso llevando a cabo una intervención en el aula.

  12. Aplicación de las Ciencias Sociales en alumnos con Necesidades Educativas Especiales en Educación Primaria

    OpenAIRE

    Delgado del Val, Ana María

    2014-01-01

    El trabajo que se ha realizado, como su nombre indica se ha centrado en la aplicación de las ciencias sociales en una niña de 6 años con necesidades educativas especiales, que según el informe psicopedagígico, ha sido diagnosticada de artrogriposis congénita, tipo displasia opercular bilateral, matriculada en Primero de Educación Primaria. [...

  13. IL SAPERE CARTOGRAFICO AL CUORE DEL PROCESSO DI APPRENDIMENTO E DI FORMAZIONE NELLA SCUOLA PRIMARIA E SECONDARIA

    OpenAIRE

    Calandra, Lina Maria

    2016-01-01

    A partire dall’idea che la carta geografica rappresenta una espressione del controllo cognitivo e simbolico della realtà, è possibile ridefinire le caratteristiche della carta geografica da mettere in evidenza e/o da far emergere nel processo di apprendimento in cartografia nella Scuola Primaria e Secondaria. Nella prospettiva di problematizzare l’approccio alla carta, due obiettivi diventano centrali: 1) capire il funzionamento della carta, ossia il meccanismo attraverso il quale...

  14. Angina de pecho con arterias angiográficamente normales: características epidemiológicas y clínicas

    Directory of Open Access Journals (Sweden)

    Oswaldo Gutiérrez Sotelo

    2002-12-01

    Full Text Available Introducción: Las lesiones obstructivas por arterioesclerosis coronaria genera diversos síndromes coronarios. Sin embargo, un subgrupo de pacientes con angina de pecho y alteraciones electrocardiográficas no presenta dichas lesiones, en el que se incluyen el vasoespasmo coronario, la angina microvascular, los puentes musculares y otras condiciones. En este estudio se evaluaron las principales características clínicas y electrocardiográficas de este grupo de pacientes. Material y métodos: Se incluyeron pacientes con cualquier síndrome coronario y angiografía coronaria sin lesiones obstructivas. Se consignaron los factores de riesgo cardiovascular, los síntomas de presentación, alteraciones electrocardiográficas y ecocardiográficas y los fármacos utilizados. Resultados: Se reclutaron 26 casos, 13 hombres y 13 mujeres con edad promedio de 56.6 años (rango 16 - 78. Se presentó angina microvascular en 16 casos, vasoespasmo coronario en 8, uno con un puente coronario y uno con flujo lento. Como síntomas se observó disnea en 18 pacientes, angor típico en 19 y angor atípico en 7. El electrocardiograma de reposo fue anormal en 18 pacientes, y el de esfuerzo en 13 casos. De 19 ecocardiogramas, 9 fueron anormales. Los fármacos más utilizados fueron los betabloqueadores, los bloqueadores de los canales del calcio y los nitratos. Conclusiones: Los pacientes con síndromes coronarios y angiografía coronaria sin lesiones obstructivas presentan frecuentemente factores de riesgo coronario, no hay diferencia de género y los exámenes auxiliares son anormales lo que motiva la realización de la angiografía.lntroduction: Coronary arteriosclerosis lesions induce several coronary syndromes. Some patients suffer angina pectoris with abnormal electrocardiograms with no obstructive plaques in the angiogram. This group includes coronary vasospasm, micro vascular angina, muscle bridges and others. This study evaluates the most important clinical

  15. Confiabilidade de sintomas sugestivos de angina em pacientes com doença pulmonar obstrutiva crônica Confiabilidad de síntomas sugestivos de angina en pacientes con enfermedad pulmonar obstructiva crónica Reliability of symptoms suggestive of angina in patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Yilmaz Gunes

    2009-05-01

    baseline clinical characteristics who had undergone diagnostic coronary angiography for the first time were reviewed retrospectively. RESULTS: The frequency of significant CAD was significantly lower in COPD patients than in the control group (52.8% vs. 80.2%, p<0.001. Frequencies of CAD risk factors (older age, hypertension, diabetes, smoking history were significantly more frequent among COPD patients having significant CAD. Among patients reporting stable angina pectoris, significant CAD was detected in 32.7% of COPD patients and 71.0% of non-COPD patients (p<0.001. However, among the patients with a diagnosis of unstable angina pectoris, significant CAD was detected in 87.5% of COPD patients and 90.2% of non-COPD patients (p=0.755. CONCLUSION: Diagnosis of CAD in COPD patients by symptomatology may be difficult. However, clinical diagnosis of CAD in the setting of unstable angina is accurate in most of the COPD patients. Therefore, further noninvasive diagnostic methods or careful follow up may be more appropriate for COPD patients reporting stable angina pectoris.

  16. Recent advances in the management of chronic stable angina I: Approach to the patient, diagnosis, pathophysiology, risk stratification, and gender disparities

    Directory of Open Access Journals (Sweden)

    Richard Kones

    2010-07-01

    Full Text Available Richard KonesThe Cardiometabolic Research Institute, Houston, Texas 77054 USAAbstract: The potential importance of both prevention and personal responsibility in ­controlling heart disease, the leading cause of death in the USA and elsewhere, has attracted renewed ­attention. Coronary artery disease is preventable, using relatively simple and inexpensive lifestyle changes. The inexorable rise in the prevalence of obesity, diabetes, dyslipidemia, and ­hypertension, often in the risk cluster known as the metabolic syndrome, drives the ­ever-increasing incidence of heart disease. Population-wide improvements in personal health habits appear to be a fundamental, evidence based public health measure, yet numerous barriers prevent implementation. A common symptom in patients with coronary artery disease, classical angina refers to the typical chest pressure or discomfort that results when myocardial oxygen demand rises and coronary blood flow is reduced by fixed, atherosclerotic, obstructive lesions. Different forms of angina and diagnosis, with a short description of the significance of pain and silent ischemia, are discussed in this review. The well accepted concept of myocardial oxygen imbalance in the genesis of angina is presented with new data about clinical pathology of stable angina and acute coronary syndromes. The roles of stress electrocardiography and stress myocardial perfusion scintigraphic imaging are reviewed, along with the information these tests provide about risk and prognosis. Finally, the current status of gender disparities in heart disease is summarized. Enhanced risk stratification and identification of patients in whom procedures will meaningfully change management is an ongoing quest. Current guidelines emphasize efficient triage of patients with suspected coronary artery disease. Many experts believe the predictive value of current decision protocols for coronary artery disease still needs improvement in order to

  17. Terapia celular associada à revascularização transmiocárdica laser como proposta no tratamento da angina refratária Cell therapy plus transmyocardial laser revascularization: a proposed alternative procedure for refractory angina

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    Luís Alberto Oliveira Dallan

    2008-03-01

    Full Text Available OBJETIVO: É descrita uma proposição cirúrgica para o tratamento de pacientes com doença arterial coronária (DAC terminal, não mais passíveis de revascularização miocárdica convencional. Constitui-se na revascularização transmiocárdica com raios laser (RTML, associada ao emprego de células progenitoras hematopoiéticas autólogas (CPH. MÉTODOS: Nove pacientes (oito homens, 65±5 anos, com as características supracitadas foram submetidos ao procedimento combinado. Além da avaliação clínica, o protocolo incluiu o estudo da perfusão miocárdica através da ressonância cardíaca (RMC sob estresse farmacológico, antes e seis meses após a intervenção cirúrgica. Procedeuse à RMTL através de minitoracotomia esquerda e utilização de laser de CO2, com média de 11±3 tiros por paciente. As CPH foram obtidas por punção medular, seguindo-se sua injeção direta (1,9±0,3x10(8 células/paciente em múltiplas áreas do miocárdio isquêmico. RESULTADOS: Não ocorreram óbitos ou complicações imediatas decorrentes dos procedimentos. Um paciente faleceu no segundo ano de pós-operatório, de causa não cardíaca (choque séptico. O seguimento clínico pós-operatório desses pacientes revelou redução significativa da classe funcional de angina de 3,7±0,2 para 1,3±0,2 (pOBJECTIVE: We tested the hypothesis that TMLR combined with intramyocardial injection of BMC is safe, and may help increase the functional capacity of patient with refractory angina. METHODS: Nine patients (eight men, 65±5 years old, with refractory angina for multivessel disease and previous myocardial revascularization procedures (CABG/PCI, not candidates for another procedure due to the extension of the disease were enrolled. TMLR (11±3 laser drills was performed via a limited thoracotomy using a CO2 Heart Laser System. BMC were obtained immediately prior to surgery, and the lymphomonocytic fraction separated by density gradient centrifugation. During

  18. La investigación y la evolución reciente de la atención primaria

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    Palomo L.

    2002-01-01

    Full Text Available La atención primaria en España ha pasado de una etapa de desarrollo florido, en la década de los ochenta, a otra de estancamiento en los noventa, caracterizada por la escasa creatividad, por la rutinización de las tareas y por la puesta en marcha de carteras de servicios y contratos programa. Por otra parte, los recientes cambios en la orientación de la investigación promovida desde la administración sanitaria, a favor de la investigación básica y en detrimento de la investigación en servicios y la epidemiología clínica, contrastan con la importancia de la atención primaria como ámbito natural de abordaje de numerosos agentes causales y prácticas de riesgo para la salud. A pesar de estas limitaciones, la cultura de la investigación ya se ha instalado en un buen número de centros de salud y de farmacias, y la investigación en atención primaria ha ido teniendo una mayor presencia en las revistas científicas. Sin embargo, es necesario gestionar la investigación, también desde las estructuras de atención primaria, de manera específica y diferenciada, favoreciendo la priorización, la evaluación y la responsabilidad mediante fórmulas organizativas flexibles y sistemas de información específicos. Ello debería incluir fórmulas de contratación y de relación laboral flexibles, que permitan la dedicación a la investigación, siquiera a tiempo parcial, así como modelos de carrera profesional que reconozcan las actividades de investigación y docencia. Las asociaciones científicas y profesionales de la atención primaria tienen ante sí el reto de mantener proyectos de investigación activos, incrementar su presencia entre los profesionales, emitir su opinión ante los problemas del sector y reforzar su organización y comunicación.

  19. Short‐term and long‐term outcomes in 133 429 emergency patients admitted with angina or myocardial infarction in Scotland, 1990–2000: population‐based cohort study

    OpenAIRE

    Capewell, S; Murphy, N F; MacIntyre, K.; Frame, S; Stewart, S.; Chalmers, J.W.T.; Boyd, J.; Finlayson, A; Redpath, A.; McMurray, J J V

    2006-01-01

    Objective: To analyse short- and long-term outcomes and prognostic factors in a large population-based cohort of unselected patients with a first emergency admission for suspected acute coronary syndrome between 1990 and 2000 in Scotland. Methods: All first emergency admissions for acute myocardial infarction (AMI) and all first emergency admissions for angina (the proxy for unstable angina) between 1990 and 2000 in Scotland (population 5.1 million) were identified. Survival to five years...

  20. Syndrome of diminished vasodilator reserve of the coronary microcirculation (microvascular angina or syndrome X): Diagnosis by combined atrial pacing and thallium 201 imaging--a case report

    Energy Technology Data Exchange (ETDEWEB)

    Magarian, G.J.; Palac, R.; Reinhart, S. (Veterans Administration Medical Center, Portland, OR (USA))

    1990-08-01

    Patients with angina-like chest pain without evidence of epicardial coronary artery disease or coronary arterial vasospasm are becoming increasingly recognized. These are often related to noncardiac causes including esophageal, musculoskeletal, and hyperventilatory or panic states. However, recently a subgroup of such patients are being recognized as having true myocardial ischemia and chest pain on the basis of diminished coronary microvascular vasodilatory reserve (microvascular ischemia or Syndrome X). The authors describe such a patient who was found to have replication of anginal pain associated with a reversible ischemic defect on thallium 201 imaging during atrial pacing, suggesting ischemia in this myocardial segment. Resolution of angina and ST segment electrocardiographic changes of ischemia occurred with cessation of pacing. We believe this is the first report of a patient with this form of myocardial ischemia diagnosed by this method and should be considered in patients with anginal chest pain after significant coronary artery disease and coronary vasospasm have been excluded.

  1. Syndrome of diminished vasodilator reserve of the coronary microcirculation (microvascular angina or syndrome X): Diagnosis by combined atrial pacing and thallium 201 imaging--a case report

    International Nuclear Information System (INIS)

    Patients with angina-like chest pain without evidence of epicardial coronary artery disease or coronary arterial vasospasm are becoming increasingly recognized. These are often related to noncardiac causes including esophageal, musculoskeletal, and hyperventilatory or panic states. However, recently a subgroup of such patients are being recognized as having true myocardial ischemia and chest pain on the basis of diminished coronary microvascular vasodilatory reserve (microvascular ischemia or Syndrome X). The authors describe such a patient who was found to have replication of anginal pain associated with a reversible ischemic defect on thallium 201 imaging during atrial pacing, suggesting ischemia in this myocardial segment. Resolution of angina and ST segment electrocardiographic changes of ischemia occurred with cessation of pacing. We believe this is the first report of a patient with this form of myocardial ischemia diagnosed by this method and should be considered in patients with anginal chest pain after significant coronary artery disease and coronary vasospasm have been excluded

  2. Percutaneous coronary excimer laser angioplasty in patients with stable and unstable angina pectoris. Acute results and incidence of restenosis during 6-month follow-up.

    Science.gov (United States)

    Karsch, K R; Haase, K K; Voelker, W; Baumbach, A; Mauser, M; Seipel, L

    1990-06-01

    A clinical study was conducted to evaluate the efficacy and safety of percutaneous coronary excimer laser angioplasty in 60 patients with coronary artery disease. Forty-nine patients had stable exertional angina, and 11 patients had unstable angina despite medical therapy. A novel 1.4-mm diameter catheter with 20 quartz fibers of 100-microns diameter each arranged concentrically around a central lumen suitable for a 0.014-in. flexible guide wire was coupled to an excimer laser. A commercial excimer laser emitting energy at a wavelength of 308 nm with a pulse duration of 60 nsec was used. The laser was operated at 20 Hz. Mean energy transmission was 30 +/- 5 mJ/mm2. In five of the 60 patients, laser angioplasty was not attempted. In 23 patients with laser ablation alone, percent stenosis decreased from 76 +/- 14% before to 27 +/- 17% after ablation and was 34 +/- 15% at the early follow-up angiogram. In 32 patients, additional balloon angioplasty was performed because of vessel closure after laser ablation in 11 and an insufficient qualitative result in 21 patients. Of the 11 patients with unstable angina, one patient died due to vessel closure 3 hours after intervention, and two patients developed a myocardial infarction. In 22 of 47 patients with late follow-up angiography, restenosis within the 6-month follow-up period occurred. Rate of restenosis was higher in patients treated with laser ablation and balloon angioplasty (16 of 28) than in patients treated with laser ablation alone (six of 19). These results suggest that coronary excimer laser angioplasty for ablation of obstructive lesions is feasible and safe in patients with stable angina. However, development of new catheter systems is necessary for an improved success rate. PMID:2344680

  3. Serum high-sensitivity C-reaction protein and heart fatty acid binding protein level and cardiac accidents in patients with unstable angina pectoris

    Institute of Scientific and Technical Information of China (English)

    朱红秋

    2006-01-01

    Objective To investigate the relationship between serum high-sensitivity C-reaction protein (hs-CRP) and heart fatty acid binding protein (h-FABP) on cardiac accidents in patients with unstable angina pectoris (UAP). Methods Serum levels of hs-CRP, h-FABP, cardiac troponin-Ⅰ(cTn-Ⅰ) and creatine kinase MB isoenzyme (CK-MB) were measured and cardiac accidents within 2 weeks after the test were observed in 74 patients (male

  4. Virtual histology study of atherosclerotic plaque composition in patients with stable angina and acute phase of acute coronary syndromes without ST segment elevation

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    Ivanović Miloš

    2013-01-01

    Full Text Available Introduction. Rupture of vulnerable atherosclerotic plaques is the cause of most acute coronary syndromes (ACS. Postmortem studies which compared stable coronary lesions and atherosclerotic plaques in patients who have died because of ACS indicated high lipid-core content as one of the major determinants of plaque vulnerability. Objective. Our primary goal was to assess the potential relations of plaque composition determined by IVUS-VH (Intravascular Ultrasound - Virtual Histology in patients with stable angina and subjects in acute phase of ACS without ST segment elevation. Methods. The study comprised of 40 patients who underwent preintervention IVUS examination. Tissue maps were reconstructed from radio frequency data using IVUS-VH software. Results. We analyzed 53 lesions in 40 patients. Stable angina was diagnosed in 24 patients (29 lesions, while acute phase of ACS without ST elevation was diagnosed in 16 patients (24 lesions. In the patients in acute phase of ACS without ST segment elevation IVUS-VH examination showed a significantly larger area of the necrotic core at the site of minimal lumen area and a larger mean of the necrotic core volume in the entire lesion comparing to stable angina subjects (1.84±0.90 mm2 vs. 0.96±0.69 mm2; p<0.001 and 20.94±15.79 mm3 vs. 11.54±14.15 mm3; p<0.05 respectively. Conclusion. IVUS-VH detected that the necrotic core was significantly larger in atherosclerotic lesions in patients in acute phase of ACS without ST elevation comparing to the stable angina subjects and that it could be considered as a marker of plaque vulnerability.

  5. Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina

    OpenAIRE

    Heng-Jung Hsu; Chiung-Hui Yen; Kuang-Hung Hsu; I-Wen Wu; Chin-Chan Lee; Chiao-Yin Sun; Chia-Chi Chou; Chun-Yu Chen; Shih-Ying Yang; Chi-Jen Tsai; Mai-Szu Wu; Ming-Jui Hung

    2014-01-01

    The prevalence of coronary vasospasm and also the factors associated with coronary vasospasm in CKD is still unclear. In this cross-sectional study of 859 consecutive CKD patients with angina pectoris received coronary catheterization, we evaluated the factors associated with coronary vasospasm. Patients with vasospasm were older and had higher peripheral blood white cell counts, higher peripheral blood monocyte cell counts, higher haemoglobin levels, higher hs-CRP levels, and lower levels of...

  6. An effective tool to detect lesions causing unstable angina with multivessel disease. Iodine-123-betamethyl-p-iodophenyl-pentadecanoic acid single photon emission computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Fukuzawa, Shigeru; Inagaki, Masayuki; Morooka, Shigeru; Inoue, Toshihisa; Sugioka, Juji; Ozawa, Shun [Funabashi Municipal Medical Center, Chiba (Japan)

    1996-10-01

    Radiolabeled fatty acids such as iodine-123-betamethyl-p-iodophenyl-pentadecanoic acid (BMIPP) have unique metabolic properties suggesting potential use as myocardial perfusion tracers. The uptakes of BMIPP and thallium 201 were compared using single photon emission computed tomography (SPECT) in 24 patients displaying unstable angina with multivessel disease at a mean of 3.4 days after admission. Coronary angiography was performed within a week. Uptake was considered normal if the activity was greater than 80% of the normal area, mildly reduced if 50% to 79%, and severely reduced if less than 50%. The regional activities in four quadrants in short-axis slices were measured from basal, mid and apical sets. We attempted to identify the causative lesion on dual SPECT imaging. We planned the following management of each patient based on the results of the dual SPECT study. BMIPP activity imaging found 4 segments (1.4%) with severe decrease, 70 (24.3%) with mild decrease, and 214 (74.3%) with normal uptake. In contrast, Tl activity imaging showed normal uptake in 68 of 74 abnormal BMIPP activity segments. Furthermore, all segments with abnormal BMIPP uptake were matched with locations of coronary artery stenosis by coronary angiography. Accordingly, coronary revascularization (percutaneous transluminal coronary angioplasty, coronary artery bypass grafting) was performed based on BMIPP SPECT. Reductions in BMIPP activity were common in patients with unstable angina with multivessel disease. BMIPP SPECT is an excellent tool for detecting the causative lesion in unstable angina. The subsequent intervention could be performed with less risk based on the strategy of dilating the only causative lesion which was detected by the BMIPP SPECT in patients with multivessel disease displaying unstable angina. (author)

  7. Efficacy of nifedipine and metoprolol in the early treatment of unstable angina in the coronary care unit: Findings from the Holland Interuniversity Nifedipine/metoprolol Trial (HINT)

    OpenAIRE

    Lubsen, J; Tijssen, J.G.P.; HINT Research Group

    1987-01-01

    A multicenter, double-blind, placebo-controlled, randomized trial of nifedipine, metoprolol and their combination was conducted in 338 patients with unstable angina (hospital admission diagnosis) who had not previously received treatment with a β blocker. In addition, nifedipine was compared with placebo in 177 patients who were receiving β blockers upon hospital admission. The main outcome event was the recurrence of ischemia or progression to myocardial infarction within 48 hours. Trial med...

  8. Riesgo en la zona andina tropical por laderas inestables

    OpenAIRE

    Duque Escobar, Gonzalo

    2000-01-01

    Las presentes notas relacionadas con la definición de riesgo y amenaza, y la aplicación de estos conceptos para eventos como los relacionados con la inestabilidad de las vertientes, pueden tener importancia para las comunidades de la región andina. Este trabajo se ocupa de una de las amenazas más importantes del medio tropical andino: los deslizamientos de tierra vistos desde la óptica de los desastres naturales. Se definen los movimientos de masas. Luego se discuten los parámetros de la ines...

  9. Un sistema internacional inestable con dominio de los Estados Unidos

    Directory of Open Access Journals (Sweden)

    Pierre Gilhodes

    2004-11-01

    Full Text Available Con la imposición de la agenda única de terrorismo y la invasión a Iraq ¿se consolidó Estados Unidos como potencia mundial? o con el ascenso de China y los avances constitucionales europeos podríamos avanzar hacia una nueva división del mundo sobre bases diferentes de las de la Guerra Fría. En este caso ¿dónde se situaría AméricaLatina?

  10. Internacoes por Condicoes Sensiveis a Atencao Primaria em uma metropole brasileira

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    Tania Cristina Morais Santa Barbara Rehem

    2013-08-01

    Full Text Available Este estudo tem como objetivo descrever o perfil das Internações por Condições Sensíveis à Atenção Primária (ICSAP no município de Curitiba no período de 2005 a 2007. Foi realizado um estudo ecológico, com dados obtidos no Sistema de Informações Hospitalares. Para análise, foi utilizada a estatística descritiva. Observou-se que em Curitiba as ICSAP seguem tendência de estabilização, sendo as causas mais frequentes a angina e a insuficiência cardíaca, maior frequência para o sexo feminino e a faixa etária ≥ 65 anos. Os resultados observados assemelham-se aos de outros estudos e foram, quase na totalidade, altamente significativos do ponto de vista estatístico. Entretanto, devem ser vistos com cuidado, pois se se trata de um indicador que apresenta algumas limitações, dentre as quais a própria confiabilidade do diagnóstico e o uso de dados secundários.

  11. EVALUACIÓN DE UN PROGRAMA DE EDUCACIÓN EMOCIONAL PARA PROFESORADO DE PRIMARIA

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    Núria Pérez-Escoda

    2013-01-01

    Full Text Available En este trabajo se presenta la evaluación de un programa de educación emocional dirigido a profesores de educación primaria, mediante una investigación cuasi-experimental pre-test post-test con grupo control. Participaron de la experiencia 92 profesores de tres centros educativos de Barcelona y Lleida. El programa incidió en el desarrollo de las cinco dimensiones de la competencia emocional siguiendo el modelo de Bisquerra y Pérez (2007: conciencia, regulación, autonomía, competencia social y competencias para la vida y el bienestar. Se utilizaron diversas estrategias para la evaluación de la intervención: diversos cuestionarios antes y después de la intervención y seguimiento del formador durante el proceso. Los resultados muestran, por un lado, una mejora significativa de la competencia emocional de los participantes al final de la experiencia y sugieren, por otro lado, la eficacia del programa en el desarrollo de la competencia emocional de los docentes así como en la mejora del clima institucional.

  12. Inmunodeficiencias primarias por déficit de anticuerpos en adultos

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    María Mercedes Bello Rodríguez

    2014-10-01

    Full Text Available Se realizó una investigación sobre los pacientes con inmunodeficiencias primarias por déficit de anticuerpos, atendidos en el servicio de inmunología del Hospital General “Dr. Ernesto Guevara” de Las Tunas, con el objetivo de caracterizar las inmunodeficiencias por déficit de anticuerpos en pacientes adultos, atendiendo al tipo de inmunoglobulina afectada, el sexo y la edad, así como las principales manifestaciones clínicas. Se evaluaron un total de diez pacientes tratados por esta causa entre los años 2005 y 2013. Para la evaluación de los resultados se utilizó el análisis de frecuencias simple. Las inmunodeficiencias diagnosticadas se correspondieron en un 50% con el déficit de las tres clases de inmunoglobulinas. Predominó el sexo masculino en un 70% y las edades más afectadas se correspondieron con la cuarta y quinta décadas de la vida. Las infecciones respiratorias y digestivas fueron las más frecuentes (80%, tanto por gérmenes bacterianos como virales, la infección por Giardia lamblia también apareció muy frecuentemente en los pacientes estudiados

  13. Clima social, prosocialidad y violencia como predictores de inadaptación escolar en primaria

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    Cira Carrasco

    2010-12-01

    Full Text Available En este trabajo se pretende analizar la aportación que hacen la percepción del clima social, el comportamiento prosocial y la violencia escolar cotidiana sufrida y observada, informadas por parte del alumnado para predecir la adaptación socioemocional informada por profesores/as y padres o madres. Los participantes son 88 alumnos/as de 8-10 años de edad, de un colegio de la provincia de Málaga. Los resultados muestran que el alumnado evaluado presenta valores normalmente bajos en variables que indican inadaptación escolar y valores normativos en variables que se asocian a una buena adaptación escolar y social. Las correlaciones entre las variables predictoras y criterio muestran dos patrones diferentes: mientras que los datos de padres se asocian más activamente a las variables clima social y violencia sufrida en el caso de los profesores son prosocialidad y violencia sufrida. Los análisis de regresión demuestran también dos patrones diferentes para padres y para profesores, poniendo de manifiesto la importancia que tiene la violencia cotidiana sufrida en los resultados de adaptación o inadaptación escolar y social en alumnado que está en segundo ciclo de Educación Primaria, y la relevancia del comportamiento prosocial para predecir buenos resultados en el ámbito académico.

  14. ESTUDIO DE LOS ENFOQUES DE ENSEÑANZA EN PROFESORADO DE EDUCACIÓN PRIMARIA

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    Fuensanta Hernández Pina

    2012-01-01

    Full Text Available A lo largo de las tres últimas décadas la investigación sobre los enfoques de enseñanza se ha incrementado considerablemente. En los estudios se han identificado dos perfiles de enfoques, elenfoque basado en el aprendizaje y el enfoque basado en la enseñanza. El primero se centra en la enseñanza como facilitadora del aprendizaje de los estudiantes, mientras que la segunda se centra en la enseñanza como una transmisión del conocimiento. El objetivo del presente estudio ha sido explorar los enfoques de enseñanza de 32 profesores de educación primaria. Los resultados indican que el 46.9% de los profesores emplean un enfoque centrado en el aprendizaje y el 53.1% en la enseñanza. Por otrolado, analizamos la correlación entre las subescalas del cuestionario, intenciones y estrategias. Los resultados sobre la teoría de enfoques de enseñanza no es concluyentes ya que algunos profesores combinan subescalas del enfoque basado en el aprendizaje con subescalas del enfoque basado en la enseñanza, haciendo la coherencia dentro de los enfoques disonante.

  15. Non-invasive diagnostic workup of patients with suspected stable angina by combined computed tomography coronary angiography and magnetic resonance perfusion imaging

    International Nuclear Information System (INIS)

    The background of this study was to evaluate additional adenosine magnetic resonance perfusion (MRP) imaging in the diagnostic workup of patients with suspected stable angina with computed tomography coronary angiography (CTCA) as first-line diagnostic modality. Two hundred and thirty symptomatic patients (male, 52%; age, 56 year) with suspected stable angina underwent CTCA. In patients with a stenosis of >50% as visually assessed, MRP was performed and the quantitative myocardial perfusion reserve index (MPRI) was calculated. Coronary flow reserve (CFR) using invasive coronary flow measurements served as the standard of reference. CTCA showed non-significant coronary artery disease (CAD) in 151/230 (66%) patients and significant CAD in 79/230 patients (34%), of whom 50 subsequently underwent MRP and CFR. MRP showed reduced perfusion in 32 patients (64%), which was confirmed by CFR in 27 (84%). All 18 cases of normal MRP (36%) were confirmed by CFR. The positive likelihood ratio of MRP for the presence of functional significant disease in patients with a lesion on CTCA was 4.49 (95% confidence interval [CI] 2.12-9.99). The negative likelihood ratio was 0.05 (95% CI 0.01-0.34). CTCA as first-line diagnostic modality excluded coronary artery disease in a high percentage of patients referred for diagnostic workup of suspected stable angina. MRP made a significant contribution to the detection of functional significant lesions in patients with a positive CTCA. (author)

  16. Comparative study between patients with infarction and angina about the fear of pain, anxiety pain symptoms, heart focused anxiety, psychopathology and hostility

    Directory of Open Access Journals (Sweden)

    Bakella P.

    2010-10-01

    Full Text Available Background: To examine the fear of pain, anxiety pain symptoms, heart focused anxiety, psychopathology and hostility between patients with infarction and angina. Method: Subjects were 104 patients with infarction or angina, who completed the Hostility and Direction of Hostility Questionnaire, the Symptom Checklist-90-R, Cardiac Anxiety Questionnaire, the Pain Anxiety Symptoms Scale-20 and the Fear of Pain Questionnaire – III. Results: For all patients higher levels of fear and anxiety of pain, heart-focused anxiety psychopathology, and a tendency to develop a hostile attitude were observed. For angina group higher levels of fearfull thinking and total PASS-20, avoidance CAQ, somatization and anxiety (SCL-90. In addition, all patients were found to be significantly correlated (P< .005 with sex, fearfull PASS-20, physiological responses PASS-20, total PASS-20, avoidance CAQ, somatization SCL-90, anxiety SCL-90 Conclusion: There is a variety of general factors that may promote the development of cardiophobia. These processes are likely nonspecific in the sense that they increase the chance of negative emotional responding and poor affect regulatory strategies. For persons exposed to cardiac-related illnesses or persons who model the potential dangers of cardiac-related sensations, there may be an enhanced specificity to that general vulnerability.

  17. Pharmaceutical care for patients with unstable angina%不稳定性心绞痛患者的药学监护

    Institute of Scientific and Technical Information of China (English)

    牟燕; 王清; 张勇; 李宏建

    2011-01-01

    Unstable angina (UA) is a common coronary heart disease with the clinical symptom situated between stable angina and acute myocardial infarction. For the complexity of its drug treatment, the clinical pharmaceutical care for patients with UA is very important. In this article, to further optimize the therapeutic project and ensure the safety of drug use, the contents of pharmaceutical care were discussed from the following four aspects respectively: undergoing anti-ischemia therapy, antiplatelet and anticoagulant therapy, lipid adjusting and plaque stabilizing therapy, and simultaneous therapy for some other disease.%不稳定性心绞痛(unstable angina,UA)是介于稳定性心绞痛与急性心肌梗死之间的一组临床综合征,其治疗药物十分复杂,临床药学监护尤为重要.本文结合实例,对抗心肌缺血治疗、抗血小板与抗凝治疗、调脂稳定斑块治疗、合并其他疾病用药时等情况下的药学监护内容进行逐一讨论,以期为该疾病的临床药学工作提供思路,优化临床治疗方案设计,保障患者的用药安全.

  18. Resolution of Angina Pectoris and Improvement of the Coronary Flow Reserve after Ranolazine Treatment in a Woman with Isolated Impaired Coronary Microcirculation

    Directory of Open Access Journals (Sweden)

    Alessandro Santoro

    2013-01-01

    Full Text Available In a 61-year-old woman with well controlled arterial hypertension, hypercholesterolemia, and smoke and suffering from recurrent angina pectoris despite angiographically normal epicardial coronary vessels and maximal therapy, the replacement of nitrates with novel antiangina drug ranolazine, after 6-month therapy, induced a complete relief of angina and a relevant rising of the transthoracic Doppler-derived coronary flow reserve (CFR. The present clinical case underlines therefore how in patients with chronic ischemic heart disease without epicardial coronary stenosis ranolazine can induce an improvement till the complete solution of the angina symptoms and a substantial increase of CFR as expression of the enhancement of the microvascular coronary function. The improvement of both symptoms and coronary microvascular function is strictly linked to the mechanism of action of the drug. Ranolazine induces in fact a reduction of the intracellular late sodium current that leads to a reduction of the intracellular calcium concentration thus producing a better myocardial diastolic relaxation process which in its turns enhances the myocardial perfusion. The ranolazine acts therefore as a lusitropic drug that improves the diastolic dysfunction and the segmental ischemia thus affecting one of the first steps of the ischemic cascade.

  19. SISTEMATIZACION DE LA EXPERIENCIA EN LA FORMACIÓN DE ASISTENTE TÉCNICO EN ATENCIÓN PRIMARIA EN SALUD

    OpenAIRE

    Olga Sánchez Charpentier

    2012-01-01

    Este artículo presenta la sistematización de la experiencia vivida por la Escuela de Enfermería respecto de la formación de Asistentes Técnicos de Atención Primaria de Salud (ATAPS) durante el periodo 2003 - 2011. Inicialmente, en Costa Rica y en los años 60, surgen los primeros grupos de asistentes en atención primaria; de su capacitación se encargaban los y las enfermeras del Programa de Atención Primaria del Ministerio de Salud y esta tomaba entre tres y cinco meses. A partir de los años 9...

  20. Validación de un modelo pronóstico para pacientes pluripatológicos en atención primaria: Estudio PROFUND en atención primaria

    OpenAIRE

    Pilar Bohórquez Colombo; María Dolores Nieto Martín; Beatriz Pascual de la Pisa; M. José García Lozano; M. Ángeles Ortiz Camúñez; Máximo Bernabéu Wittel

    2014-01-01

    Objetivo: Validar el índice PROFUND, en pacientes pluripatológicos (PP) en atención primaria. Diseño: Estudio longitudinal prospectivo multicéntrico, seguimiento 2 años. Emplazamiento: Tres centros de salud de la provincia de Sevilla. Sujetos: Adultos pluripatológicos, con consentimiento a participar; muestreo consecutivo. Mediciones: Variable dependiente: mortalidad (2 años). Variables independientes: sociodemográficas, clínicas, antropométricas, analíticas, prescripción farmacol...

  1. Sensitivity and related factors in iodine-123-β-methyl-p-iodophenyl-pentadecanoic acid myocardial scintigraphy to detect stable effort angina pectoris

    International Nuclear Information System (INIS)

    This study evaluated the sensitivity and the related factors in iodine-123-β-methyl-p-iodophenyl-pentadecanoic acid (BMIPP) scintigraphy to detect stable angina. The subjects were 198 patients with stable angina who underwent BMIPP before percutaneous coronary intervention or coronary bypass graft surgery. Patients with unstable angina, myocardial infarction, congestive heart failure, cardiomyopathy and vasospastic angina were excluded. After investigation of the sensitivity of BMIPP, the patients with single-vessel disease without collateral flow were classified into the normal 123I-BMIPP uptake group (normal group) or decreased 123I-BMIPP uptake group (decreased group), and various factors were compared between the two groups. Sensitivity was 61% overall, 58% in single-vessel disease, 69% in double-vessel disease, 53% in triple-vessel disease, 43% in only left main vessel disease, and 89% in left main and other vessel disease (NS). In single-vessel disease, the sensitivity was 40% in 75% coronary artery stenosis, 58% in 90% stenosis, 89% in 99% stenosis, and 69% in total occlusion (p=0.003). Comparing the decreased and normal groups, diabetes mellitus was more frequent in the normal group (14.6% vs 39.5%), minimal lumen diameter was smaller (0.75±0.37 vs 0.98±0.49 mm) and lesion length was longer in the decreased group (15.4±4.9 vs 11.6±5.5 mm). Logistic multivariate analysis showed that the independent factors were diabetes mellitus [odds ratio 0.20, 95% confidence interval (CI) 0.04-0.87, p=0.03], minimal lumen diameter (odds ratio 0.10, 95% CI 0.02-0.48, p=0.003) and lesion length (odds ratio 1.12, 95% CI 1.00-1.25, p=0.03). BMIPP is useful in stable angina patients because of the acceptable sensitivity. Diabetes mellitus, minimal lumen diameter and lesion length were independent factors associated with decreased BMIPP uptake. (author)

  2. Changes of dendritic cells and fractalkine in type 2 diabetic patients with unstable angina pectoris: a preliminary report

    Directory of Open Access Journals (Sweden)

    Qian Juying

    2011-06-01

    Full Text Available Abstract Background It has been shown that dendritic cells (DCs and fractalkine play a role in accelerating progression of the inflamed atherosclerotic lesions and plaque rupture. We evaluated the numbers and functional changes of DCs and its subsets in human type 2 diabetes with or without unstable angina pectoris (UAP. Methods The study population consisted of 39 diabetic patients (DM:18 without CAD; DM + UAP: 21 with UAP, 18 non-diabetic UAP patients (UAP, and 15 healthy control (Normal. Peripheral blood DCs and its subsets were measured by three color flow cytometry. Serum levels of fractalkine, IL-12, and IFN-α were also measured. The functional status of the monocyte-derived DCs was analyzed by flow cytometry and allogeneic mixed T lymphocytes reaction. Results The percent and absolute numbers of DCs and mDC within the total leukocyte population was similar for Normal and DM, while significantly lower in DM + UAP. pDC numbers were not significantly altered. Serum fractalkine in DM + UAP was highest among the four groups (p = 0.04 vs. UAP, p = 0.0003 vs. DM, p p = 0.01 level. Compared with DM and UAP, the costimulatory molecules CD86 and proliferation of T cells stimulated by DCs were significantly increased in DM + UAP group. Conclusions Our study suggested that increases in the fractalkine level and the number and functional changes of blood DCs might contribute to diabetic coronary atherosclerosis and plaque destabilization.

  3. Richtlinien zur Diagnostik und Therapie der instabilen Angina pectoris und des Non-Q-Wave-Myokardinfarktes: vorgeschlagene Revisionen

    Directory of Open Access Journals (Sweden)

    Huber K

    2000-01-01

    Full Text Available Die letzten Praxis-Empfehlungen der United States Agency for Health Care Policy and Research zum Thema "Diagnose und Behandlung der instabilen Angina Pectoris (IAP" stammen aus dem Jahre 1994 und wurden trotz der rasanten Fortschritte auf diesem Gebiet in den vergangenen 5 Jahren nicht erneuert. Das International Cardiology Forum (ICF hat Ende 1998 die existierenden Richtlinien diskutiert und Vorschläge gemacht, in welchen Bereichen die Diagnostik und die Therapie der IAP aufgrund der mittlerweile vorliegenden Daten modifiziert werden sollten. Es wurde übereinstimmend beschlossen, daß folgende Änderungen empfohlen werden: 1. Troponin T und Troponin I sollten die Palette der Myokardmarker im Serum für diagnostische und prognostische Zwecke erweitern; 2. niedermolekulere Heparine sollten Standard-Heparin als Antikoagulantium ersetzen; 3. neue thrombozyten-inhibierende Substanzen sollten zusätzlich zu Aspirin zur Anwendung kommen; 4. die Verwendung von cholesterinsenkenden Medikamenten in der Langzeitbehandlung dieser Patienten ist sinnvoll. In der vorliegenden Arbeit wurden die Hintergründe für die vorgerschlagenen Revisionen diskutiert, und es wird auf rezente wissenschaftliche Publikationen Bezug genommen.

  4. Left ventricular dysfunction during exercise in patients with angina pectoris and angiographically normal coronary arteries (syndrome X)

    International Nuclear Information System (INIS)

    Left ventricular function during exercise and recovery was investigated in patients with angina pectoris, ST segment depression during exercise and angiographically normal coronary arteries (syndrome X) using a continuous left ventricular function monitor with cadmium telluride detector (CdTe-VEST). Fourteen patients with syndrome X and 14 patients with atypical chest pain without ST segment depression during exercise and normal coronary arteries (control group) performed supine ergometric exercise after administration of 740-925 MBq of technetium-99m labelled red blood cells, and left ventricular function was monitored every 20 s using CdTe-VEST. Left ventricular ejection fraction (EF) response was impaired (≤ 5% increase from rest to peak exercise) in 11 or 14 patients with syndrome X but in none of the control patients. Resting EF was similar in the two groups (62.1% ± 6.7% in patients with syndrome X, 61.9% ± 6.2% in controls); however, EF increase from rest to peak exercise was lower in syndrome X (-3.1 ± 9.5% vs 14.7% ± 7.4%). After cessation of exercise, all patients showed rapid EF increase over baseline and this EF overshoot was lower (19.3% ± 8.3% vs 26.4% ± 7.3%) with the time to EF overshoot longer (114 ± 43 s vs 74 ± 43 s, P < 0.05) in patients with syndrome X. (orig./MG)

  5. Evaluation of coronary artery remodeling in patients with acute coronary syndrome and stable angina by multislice computed tomography

    International Nuclear Information System (INIS)

    Multislice computed tomography (MSCT) was used to evaluate coronary artery remodeling in patients with acute coronary syndrome (ACS) and stable angina (SA). MSCT was performed in 31 patients with ACS and 26 patients with SA and intravascular ultrasound (IVUS) was performed in 28 of these 57 patients. In both the MSCT and IVUS analyses, coronary artery remodeling was assessed by the remodeling index (RI): RI>1.10 was defined as positive coronary artery remodeling (PCAR) and RI<0.95 was defined as negative coronary artery remodeling (NCAR). The RI assessed by MSCT closely correlated with that of IVUS (r=0.86, n=28). The vessel area at the region of maximum luminal narrowing was also comparable between the MSCT and IVUS measurements (r=0.92). PCAR was present in 19 patients (61.3%) with ACS, but in none of the patients with SA (p<0.0001). However, NCAR was present in only 1 patient with ACS (3.2%), but was present in 18 patients (62.9%) with SA. The RI was significantly larger in patients with ACS (1.19±0.18) than in those with SA (0.89±0.10, p<0.0001). MSCT accurately assesses coronary artery remodeling. (author)

  6. Assessment of myocardial fatty acid metabolism in patients with vasospastic angina using {sup 123}I-BMIPP myocardial SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Kazuki; Sugihara, Hiroki; Terada, Kouji [Kyoto Prefectural Univ. of Medicine (Japan)] [and others

    1995-10-01

    Myocardial perfusion and fatty acid metabolism may be unpaired in the patients of vasospastic angina (VSA), because abnormal regional wall motion of left ventricle has been shown in some cases of VSA without apparent history of myocardial infarction. To study the clinical utility of {sup 123}I-BMIPP scintigraphy in diagnosis of myocardial ischemia in VSA, both {sup 123}I-BMIPP (rest) and {sup 201}Tl (exercise) SPECT were performed in the 20 patients of VSA diagnosed by coronary angiography. Defect scores were calculated visually from the 17 segments of myocardial images and were compared with patient`s anginal history, period from last attack, numbers of attack, left ventricular (LV) ejection fraction and severity of regional LV wall motion abnormality. {sup 123}I-BMIPP SPECT images showed decreased tracer uptake in 14 cases of 20 (70%) VSA patients. Exercise {sup 201}Tl SPECT images showed decreased tracer uptake in 3 cases of 20 (15%) of patients. Severity of regional LV wall motion abnormality was correlated with defect score of BMIPP. Though total defect score of BMIPP did not correlate with patient`s anginal history, number of symptoms and LV ejection fraction, correlated inversely with period from last attack. It was suggested that {sup 123}I-BMIPP myocardial SPECT images in VSA patients showed `memories` of myocardial ischemic damages induced by vasospasm. In summary, {sup 123}I-BMIPP myocardial SPECT images could be a useful test for diagnosis and evaluation of VSA. (author).

  7. Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris

    Energy Technology Data Exchange (ETDEWEB)

    Pugliese, Francesca; Krestin, Gabriel P. [Erasmus Medical Center, Department of Radiology, Rotterdam (Netherlands); Mollet, Nico R.A.; deFeyter, Pim J. [Erasmus Medical Center, Department of Radiology, Rotterdam (Netherlands); Erasmus Medical Center, Department of Cardiology, Rotterdam (Netherlands); Runza, Giuseppe [University of Palermo, Department of Radiology, Palermo (Italy); Azienda Ospedaliera di Parma, Department of Radiology, Parma (Italy); Mieghem, Carlos van; Meijboom, Willem B.; Baks, Timo [Erasmus Medical Center, Department of Cardiology, Rotterdam (Netherlands); Malagutti, Patrizia [Erasmus Medical Center, Department of Cardiology, Rotterdam (Netherlands); University of Ferrara, Department of Cardiology, Ferrara (Italy); Cademartiri, Filippo [Erasmus Medical Center, Department of Radiology, Rotterdam (Netherlands); Azienda Ospedaliera di Parma, Department of Radiology, Parma (Italy)

    2006-03-15

    Multislice computed tomography (CT) is an emerging technique for the non-invasive detection of coronary stenoses. While the diagnostic accuracy of 4-slice scanners was limited, 16-slice CT imagers showed promising results due to increased temporal and spatial resolution. These technical advances prompted us to evaluate the diagnostic performance of 64-slice CT coronary angiography in the detection of significant stenoses (defined as {>=} 50% luminal diameter reduction) versus invasive quantitative coronary angiography (QCA). Thirty-five patients with stable angina pectoris underwent CT coronary angiography performed with a 64-slice scanner (gantry rotation time 330 ms, individual detector width 0.6 mm) prior to conventional coronary angiography. Patients with heart rates >70 beats/min received 100 mg metoprolol orally. One hundred millilitres of contrast agent with an iodine concentration of 400 mgl/ml were injected at a rate of 5 ml/s into the antecubital vein. The CT scan was triggered with the bolus tracking technique. The sensitivity, specificity and the positive and negative predictive values of 64-slice CT were 99%, 96%, 78% and 99%, respectively, on a per-segment basis. The values obtained on a per-patient basis were 100%, 90%, 96% and 100%, respectively. When referral to catheterisation is questionable, CT coronary angiography may identify subjects with normal angiograms and consistently decrease the number of unnecessary invasive procedures. (orig.)

  8. Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris

    International Nuclear Information System (INIS)

    Multislice computed tomography (CT) is an emerging technique for the non-invasive detection of coronary stenoses. While the diagnostic accuracy of 4-slice scanners was limited, 16-slice CT imagers showed promising results due to increased temporal and spatial resolution. These technical advances prompted us to evaluate the diagnostic performance of 64-slice CT coronary angiography in the detection of significant stenoses (defined as ≥ 50% luminal diameter reduction) versus invasive quantitative coronary angiography (QCA). Thirty-five patients with stable angina pectoris underwent CT coronary angiography performed with a 64-slice scanner (gantry rotation time 330 ms, individual detector width 0.6 mm) prior to conventional coronary angiography. Patients with heart rates >70 beats/min received 100 mg metoprolol orally. One hundred millilitres of contrast agent with an iodine concentration of 400 mgl/ml were injected at a rate of 5 ml/s into the antecubital vein. The CT scan was triggered with the bolus tracking technique. The sensitivity, specificity and the positive and negative predictive values of 64-slice CT were 99%, 96%, 78% and 99%, respectively, on a per-segment basis. The values obtained on a per-patient basis were 100%, 90%, 96% and 100%, respectively. When referral to catheterisation is questionable, CT coronary angiography may identify subjects with normal angiograms and consistently decrease the number of unnecessary invasive procedures. (orig.)

  9. FEATURES OF CYTOKINE PRODUCTION IN PATIENTS WITH UNSTABLE ANGINA: DEPENDENCE ON ETHNICITY IN THE REPUBLIC OF SAKHA (YAKUTIA

    Directory of Open Access Journals (Sweden)

    A. S. Golderova

    2014-07-01

    Full Text Available Abstract. We investigated levels of spontaneous and mitogen-induced cytokine production (IL-1β, IL-4, IL-6, IL-10 and IFNγ by peripheral blood cells of 24 men with unstable angina (UA, including indigenous population (n = 12, Yakuts, and a group of Russian migrants to the Republic of Sakha (n = 12. Activation of inflammatory response was revealed in the total group of patients with UA, manifesting by increase of spontaneous and induced production of the pro-inflammatory IL-1β, IL-6 cytokines, and mitogen-induced production of IFNγ. As compared with healthy individuals, spontaneous and induced production of anti-inflammatory IL-4 was decreased in UA patients, whereas the mitogen-induced production of IL-10 proved to be enhanced. Therefore, it is highly possible that a pro-atherogenic Th1-immune response is developing during UA, along with suppression of Th2-driving response. The differences revealed for different ethnic groups suggest that severity and prevalence of atherosclerotic disease, which is more common in the non-native patients, is associated with increased production of pro-inflammatory IL-1β and IL-6 cytokines.

  10. Identifying Metabolite and Protein Biomarkers in Unstable Angina In-patients by Feature Selection Based Data Mining Method

    Institute of Scientific and Technical Information of China (English)

    SHI Cheng-he; YANG Yi; WANG Wei; ZHAO Hui-hui; HOU Na; CHEN Jian-xin; SHI Qi; XU Xue-gong; WANG Juan; ZHENG Cheng-long; ZHAO Ling-yan

    2011-01-01

    Unstable angina(UA) is the most dangerous type of Coronary Heart Disease(CHD) to cause more and more mortal and morbid world wide. Identification of biomarkers for UA at the level of proteomics and metaboiomics is a better avenue to understand the inner mechanism of it. Feature selection based data mining method is better suited to identify biomarkers of UA. In this study, we carried out clinical epidemiology to collect plasmas of UA in-patients and controls. Proteomics and metabolomics data were obtained via two-dimensional difference gel electrophoresis and gas chromatography techniques. We presented a novel computational strategy to select biomarkers as few as possible for UA in the two groups of data. Firstly, decision tree was used to select biomarkers for UA and 3-fold cross validation was used to evaluate computational performances for the three methods. Alternatively, we combined independent t test and classification based data mining method as well as backward elimination technique to select, as few as possible, protein and metabolite biomarkers with best classification performances. By the method, we selected 6 proteins and 5 metabolites for UA. The novel method presented here provides a better insight into the pathology of a disease.

  11. Cribado para el trastorno bipolar en pacientes de atención primaria que presentan síntomas psicológicos

    Directory of Open Access Journals (Sweden)

    Enric Aragonès

    2015-03-01

    Conclusiones: El cribado del TB en pacientes de atención primaria con otros problemas psicológicos da lugar a una notable proporción de resultados positivos, lo que indica que puede haber una prevalencia relevante de pacientes con TB, la mayor parte de ellos no diagnosticados y no tratados adecuadamente. Es necesario profundizar en la investigación para determinar el eventual papel que puede o debe asumir la atención primaria en la detección, el diagnóstico o el manejo de este trastorno.

  12. Las actividades de primaria y ESO incluidas en libros escolares : ¿qué objetivo persiguen?, ¿qué procedimientos enseñan?

    OpenAIRE

    Martínez Losada, Cristina; García Barros, Susana

    2003-01-01

    Se analizan un total de 1.340 actividades correspondientes a textos de primaria y ESO de tres editoriales de amplia implantación, dirigidas al estudio de tres tópicos: materia, animales y vegetales. Se estudia, además de la importancia otorgada por las editoriales a estos tópicos, el objetivo que persiguen las actividades y los procedimientos que enseñan. Se detecta que en primaria se insiste más en seres vivos que en materia. La aplicación de la teoría que figura en el texto y la adquisición...

  13. ¿Cómo podemos aprender el arte en Educación Primaria? ¡Traslademos las obras de arte al aula!

    OpenAIRE

    Feliu Torruella, María

    2011-01-01

    Con este artículo pretendemos mostrar una experiencia de investigación en el aula de primaria en seis centros educativos. Dónde se han experimentado dos unidades didácticas con metodologías diferentes para verificar la incidencia de los métodos en los procesos de enseñanza y aprendizaje del arte. Palabras clave: investigación, didáctica del arte, educación primaria, metodología enseñanza.

  14. Aprendiendo a interpretar el aprendizaje de las matemáticas en educación primaria. Características en un contexto B-Learning

    OpenAIRE

    Penalva Martínez, María del Carmen; Rey Mas, Carolina; Llinares Ciscar, Salvador

    2013-01-01

    El objetivo de esta investigación es identificar características del proceso de instrumentalización del conocimiento de didáctica de la matemática de profesores de educación primaria en un curso de especialización desarrollado en un contexto b-learning. Participaron 65 maestros en un entorno de aprendizaje b-learning integrando debates virtuales y centrados en el análisis del pensamiento matemático de alumnos de educación primaria. El análisis de las participaciones en los debates virtuales y...

  15. Percepción de las competencias profesionales del docente de educación física en primaria y secundaria

    OpenAIRE

    Valle, S. del; Vega Marcos, Ricardo de la; Rodríguez, M.

    2015-01-01

    El estudio ha tenido el propósito de analizar el conocimiento de la percepción de las competencias profesionales que tiene el profesor de educación física en primaria y secundaria, como uno de los aspectos que determinan la identidad de la educación física como materia escolar, para dar respuesta al análisis del estado de la educación física desde esta perspectiva. Participaron 119 docentes de Castilla-La Mancha de primaria y secundaria, a los que se les aplicó parte de la "Escala de Percepci...

  16. Detección y prevalencia del trastorno por uso de alcohol en los centros de atención primaria de Cataluña

    OpenAIRE

    Laia Miquel; Pablo Barrio; Jose Moreno-España; Lluisa Ortega; Jakob Manthey; Jürgen Rehm; Antoni Gual

    2016-01-01

    Objetivo: Describir el grado de reconocimiento del trastorno por uso de alcohol (TUA) y dependencia de alcohol por los médicos de atención primaria (MAP) y determinar su prevalencia. Diseño: Estudio transversal. Emplazamiento: Veinte centros de atención primaria de Cataluña. Participantes y mediciones: Se encuestó a 23 MAP seleccionados al azar acerca del consumo de alcohol y otras enfermedades de sus pacientes. Se entrevistó y evaluó a 1.372 pacientes con la Composite International ...

  17. Análisis nutricional del modelo dietético en alumnos de educación primaria con estado nutricional normal

    OpenAIRE

    Beatriz Durá-Gúrpide; Teodoro Durá-Travé

    2014-01-01

    Objetivo: Realizar un análisis nutricional del modelo dietético en un grupo de alumnos de Educación Primaria (9-12 años) con estado nutricional normal. Material y métodos: Registro de consumo de alimentos de dos días lectivos consecutivos en una muestra de 353 alumnos de Educación Primaria (188 varones y 165 mujeres) con una situación nutricional normal. Se ha calculado el consumo calórico y de macronutrientes, minerales y vitaminas comparándose con las ingestas recomendadas. Resultados: El v...

  18. Influencia de la memoria verbal y la memo-ria visual sobre el rendimiento académico en Educación Primaria

    OpenAIRE

    Blanco-Cerro, Susana

    2013-01-01

    Objetivo. Estudiar la relación entre la memoria visual a corto y largo plazo, y la memoria verbal respecto al rendimiento académico en distintas áreas educativas en alumnos del ter-cer ciclo de Educación Primaria. Metodología. Para analizar las variables implicadas se ha aplicado el Test de la Figura Compleja de Rey (Meyer, 1995) y el Test de Memoria Auditiva Inmediata (Cordero, 2009) a una muestra de 30 alumnos de entre 10 y 12 años de Educa-ción Primaria. Para realizar los análisis estadíst...

  19. Serie sobre hospitalizaciones evitables y fortalecimiento de la atención primaria en salud: El caso de México

    OpenAIRE

    Gabriela Rodríguez Abrego; Beatriz Zurita; Teresita Ramírez Sánchez; José Joaquín Herrera Rojas

    2012-01-01

    La hospitalización evitable (HE) por condiciones sensibles la atención primaria (ASCS) es un indicador directo del volumen de actividad hospitalaria potencialmente prevenible mediante cuidados oportunos y efectivos en el primer nivel asistencial, y un indicador indirecto de la capacidad resolutiva del sistema de Atención Primaria a la Salud (APS), de la efectividad y calidad de los servicios, de la reducción de costos hospitalarios y mejora de la eficiencia. Se realizó medición del indicador ...

  20. Cooperar, ¿por qué y para qué? : aprendizaje cooperativo en Primaria, en el colegio Nuestra Señoa de la Providencia

    OpenAIRE

    García del Barrio, Illán

    2015-01-01

    Tratar de ofrecer una metodología activa, como es el aprendizaje cooperativo desde un punto de vista teórico y su representación real y práctica en Primaria, en el colegio Nuestra Señora de la Providencia, donde realicé los períodos de prácticas del Grado de Educación Primaria. Para ello, mostrar las ventajas y ofrecer remedios educativos para dar respuesta a las dificultades es un punto importante. También destapar el funcionamiento, recurso, estructuras, herramientas y cambios en el pensami...

  1. Influencia del desgaste profesional en el gasto farmacéutico de los médicos de atención primaria

    OpenAIRE

    Cebrià J.; Sobrequés J.; Rodríguez C.; Segura J.

    2003-01-01

    Objetivo: Determinar la influencia sobre el gasto farmacéutico por asegurado (GFPA) en atención primaria de salud de diversos factores relacionados con las características personales y profesionales de los médicos generales, y su nivel de desgaste profesional. Método: Estudio observacional transversal de 220 médicos de atención primaria de la provincia de Barcelona a quienes, por medio de entrevista directa, se administró un cuestionario validado y estructurado en dos partes: datos generales ...

  2. Estrategias y técnicas para desarrollar la expresión escrita en lengua inglesa en la etapa de Educación Primaria

    OpenAIRE

    Pellejero Torres, Gema

    2014-01-01

    En el presente trabajo se realiza una exposición acerca de la expresión escrita en inglés en Educación Primaria. Para ello analizamos su marco teórico, el currículum de primaria y varias estrategias y técnicas para el desarrollo de esta. Dada la importancia de la expresión escrita en el contexto escolar, hemos incluido una programación para poder fomentarla en la escuela.

  3. Satisfacción laboral de los profesionales de Atención Primaria del Área 10 del Insalud de Madrid

    OpenAIRE

    Fernández San Martín María Isabel; Moinelo Camporro Antonio; Villanueva Guerra Adela; Andrade Rosa Cristina; Rivera Teijido Montserrat; Gómez Ocaña Jose María; Parrilla Ulloa Olga

    2000-01-01

    FUNDAMENTO: La implantación de un modelo de calidad total requiere conocer la satisfacción laboral de los trabajadores. Pretendemos averiguar el nivel de satisfacción global y de cada uno de los trabajadores de Atención Primaria del Área 10, MÉTODOS: Estudio descriptivo transversal realizado en el Area 10 del Insalud de Madrid, Atención Primaria. Trabajan en este Área 668 profesionales sanitarios y no sanitarios. Se utiliza el cuestionario de satisfacción Font Roja, adaptado por J. Aranaz, qu...

  4. Dificultades para la escritura en alumnos de 3º de educación primaria: la disgrafía y las pruebas de diagnóstico.

    OpenAIRE

    Pérez Fernández, Rebeca

    2015-01-01

    RESUMEN: En el presente trabajo se describen los diferentes métodos, recursos y estrategias que se pueden utilizar para el tratamiento de la disgrafía desde un aula de Educación Primaria. Concretamente, se indica cómo se trata este error orientado a las pruebas de diagnóstico llevadas a cabo en un aula específica de 3º de Primaria. La disgrafía es una de las dificultades específicas relacionadas con la escritura y puede ser reconocida desde los primeros años de escolarización, lo que nos hace...

  5. Lecturas exploratorias en un sitio de internet: un estudio exploratorio en niños de cuarto y sexto grado de escuela primaria

    OpenAIRE

    Bertacchini, Patricio Román

    2013-01-01

    La pregunta general que guía el trabajo es: ¿Cuáles son los procesos cognoscitivos de estudiantes de escuela primaria frente a tareas de búsqueda de información de textos de ciencias sociales en un sitio informativo de Internet? Se indagan las lecturas de estudiantes de escuela primaria dentro de un sitio web para buscar información. Más precisamente las lecturas exploratorias de los alumnos, la selección de información, la interpretación de la misma y las diferencias y similitudes en niños d...

  6. Asociación entre las habilidades mentales primarias y el rendimiento académico en estudiantes de medicina de pregrado

    OpenAIRE

    Víctor Manuel Gómez-López; Sandra Rosales-Gracia; Griselda Marín-Solórzano

    2013-01-01

    Con el propósito de analizar la asociación que existe entre las habilidades mentales primarias cuando se ingresa a la carrera de medicina y el rendimiento académico cuando se termina el octavo semestre, se realizó un estudio observacional y retrospectivo en 121 egresados de la Licenciatura de Medicina de una escuela particular del norte de México. Las habilidades mentales primarias se consideraron como variables predictoras, en tanto el rendimiento académico se asumió como variables de result...

  7. Comprensión lectora y resolución de problemas en estudiantes de Educación Primaria Bilingüe en comunidades shipibas

    OpenAIRE

    Dulio Oseda Gago; María Cabezudo Ríos

    2014-01-01

    Objetivos: Determinar la relación entre la comprensión lectora y la resolución de problemas en estudiantes del sexto grado de educación primaria bilingüe de las comunidades shipibas del distrito de Yarinacocha, Ucayali en el 2014. Métodos: Investigación de enfoque cuantitativo, tipo básica, diseño descriptivo - correlacional. La muestra fue tomada probabilísticamente conformada por 56 estudiantes del sexto grado de Educación Primaria Bilingüe en las comunidades shipibas del distrito de Yarina...

  8. La percepción medioambiental del profesorado de primaria en el tema de la nutrición humana

    OpenAIRE

    García-Barros, Susana; Martínez Losada, Cristina; Rivadulla-López, Juan Carlos

    2010-01-01

    En este trabajo se muestra como un proyecto de tesis doctoral, dirigido a estudiar el pensamiento del profesorado de educación primaria en ejercicio y en formación sobre la nutrición humana, se acerca a la problemática ambiental. En el artículo se justifica la dimensión medioambiental de la nutrición humana que sirve de referencia para las decisiones tomadas en la metodología planteada. Así mismo se presentan unos primeros resultados, que aunque todavía limitados, ponen de manifiesto que l...

  9. Explorando la Geometría en el segundo curso del primer ciclo de educación Primaria

    OpenAIRE

    Sedó-Beneyto, Marta

    2016-01-01

    El objetivo general de este trabajo fue crear una propuesta de actividades lúdicas con la finalidad de mejorar el razonamiento geométrico de alumnos de segundo curso de primer ciclo de la etapa Primaria mediante proyectos, talleres y juegos contextualizados en su vida cotidiana. La mayoría de estas actividades fomentan la resolución de problemas para favorecer el desarrollo del pensamiento matemático y, más concretamente, del razonamiento geométrico del niño, potenciando la motivación, la coo...

  10. Conocimiento matemático para la enseñanza de la probabilidad en educación primaria

    OpenAIRE

    Gómez-Torres, Emilse; Batanero, Carmen; Contreras, José Miguel

    2014-01-01

    Esta experiencia formativa pretende desarrollar entre los participantes algunos componentes del modelo propuesto por Ball y colaboradores, en relación con contenidos probabilísticos incluidos en los currículos de educación primaria. Para llevarla a cabo se propone a los participantes una situación experimental y contextualizada que los confronte con sus propias intuiciones (correctas e incorrectas) en relación con el enfoque frecuencial de la probabilidad. Para prepararlos en la componente di...

  11. Mejora de la inteligencia emocional a través de la responsabilidad social en Educación Primaria

    OpenAIRE

    Sancho Arranz, Verónica

    2014-01-01

    Se trata de un Trabajo de Fin de Grado en el que se realiza una revisión teórica acerca de los conceptos Responsabilidad Social, Inteligencia Emocional e Inteligencia Emocional-Social, que nos servirá como base para el desarrollo de una propuesta didáctica en el tercer ciclo de Educación Primaria. El objetivo general de dicho programa didáctico es fomentar la Inteligencia Emocional mediante la realización de actividades que desarrollen la Responsabilidad Social. Además, se incluye una propues...

  12. Las máquinas en libros de texto de Educación Primaria: el caso de una editorial

    OpenAIRE

    Criado García-Legaz, Ana María; Cruz-Guzmán Alcalá, Marta; Muñoz Franco, Granada; García Carmona, Antonio

    2014-01-01

    Se presenta un estudio sobre el tratamiento curricular al tema las máquinas en libros de texto de Educación Primaria (EP). Para ello, se analizan los del área de Conocimiento del Medio, de la Editorial Anaya, para distintos cursos de la etapa. El análisis se hace desde una perspectiva exploratoria y descriptiva para determinar el grado de idoneidad o sintonía ciertos aspectos curriculares del tópico con las actuales tendencias en Didáctica de la Ciencia. Con respecto a los aspectos epistemoló...

  13. Problemas asociados a la enseñanza del contenido disoluciones durante la escolaridad primaria y secundaria

    OpenAIRE

    Veglia, Silvia; Vázquez, Griselda; Brillada, Alicia; Odetti, Héctor

    2012-01-01

    El presente trabajo de investigación tuvo como propósito conocer algunas causas por las cuales los alumnos que ingresan al Profesorado de Educación Primaria de la Escuela Normal N° 30 de la ciudad de Esperanza, Provincia de Santa Fe, no alcanzan los saberes básicos de la disciplina Química, particularmente, en relación al contenido Disoluciones. El diseño metodológico fue de corte cuantitativo y cualitativo. Se utilizaron variados instrumentos de recolección de datos: entrevistas a docentes d...

  14. EL DIRECTOR ESCOLAR NOVEL DE PRIMARIA. Problemas y retos que enfrenta en su primer año

    OpenAIRE

    JOSÉ MARÍA GARCÍA GARDUÑO; CHARLES L. SLATER; GEMA LÓPEZ GOROSAVE

    2010-01-01

    El propósito de este trabajo fue examinar los problemas y situaciones que enfrentan los nuevos directores de educación primaria. Participaron diez directores, cinco del sexo femenino y cinco del masculino, en su primer año en el cargo en un estado del norte de México. Las técnicas de recolección de datos incluyeron entrevistas individuales, un grupo de enfoque y un diario de incidentes críticos. Los resultados señalan que los principales problemas que enfrentan los nuevos directores son la ca...

  15. La problem??tica de la funci??n directiva en primaria desde posiciones encontradas: los directores frente al profesorado

    OpenAIRE

    Rodr??guez Sabiote, Clemente; Garc??a Mino, Felipe; Garc??a Vacas, Ignacio; ??lvarez Rodr??guez, Jos??

    2013-01-01

    El presente estudio, de tipo comparativo-causal, tiene como objetivo fundamental determinar si maestros y directores de las escuelas tienen o no una visi??n similar a la hora de valorar determinados aspectos relacionados con la problem??tica de la funci??n directiva en educaci??n primaria, a saber: aspectos relacionados con la responsabilidad en la convivencia y cohesi??n del centro, los procesos de reciclaje e innovaci??n del mismo, as?? como los incentivos para acceder al cargo directivo. P...

  16. Propuesta de enseñanza de lectoescritura para alumnos con TDAH de Educación Primaria

    OpenAIRE

    Gil Ortega-Calcerrada, Noemí

    2015-01-01

    Este trabajo de fin de grado desarrolla una propuesta de intervención para trabajar la lectoescritura con alumnos que padecen TDAH (Trastorno de Déficit de Atención con Hiperactividad). Dicha propuesta está planteada para ser trabajada con el alumnado del primer curso de Educación Primaria. Para ello, se parte de un marco teórico en el que se profundiza en el TDAH y su tipología. Asimismo, se aborda la lectoescritura, se ahonda en las dificultades que se plantean al trabajar este proceso con ...

  17. Propuesta de pautas y tareas para potenciar el rendimiento de alumnos con TDAH en Educación Primaria.

    OpenAIRE

    Gómez-Vidal, Núria

    2012-01-01

    En el presente trabajo se destaca el importante papel que puede asumir el maestro en el manejo del TDAH en el aula de primaria y se tiene en cuenta que a veces, por falta de conocimiento, formación e información a nivel educativo y por las implicaciones que conlleva dicho trastorno, los alumnos con TDAH pueden sufrir consecuencias negativas en su rendimiento escolar. La implicación del maestro en atender a la diversidad del alumnado, en prevenir las dificultades de aprendizaje así como en pon...

  18. Baja concordancia entre la información clínica de atención primaria y hospital

    OpenAIRE

    Concha Revilla-López; Amaia Calderón-Larrañaga; Natalia Enríquez-Martín; Alexandra Prados-Torres

    2016-01-01

    Objetivos: Medir la concordancia respecto a las enfermedades crónicas registradas en atención primaria (AP) y hospitalaria, y valorar la utilidad de sus registros asistenciales con fines de investigación. Emplazamiento: Estudio transversal retrospectivo integrando información diagnóstica de AP y hospitalaria de la población de Aragón ingresada en 2010. Participantes: Se analizó a 75.176 pacientes Intervenciones: Se analizaron coincidencias, divergencias e índice kappa de los diagnóst...

  19. Representaciones de estudiantes de primaria y secundaria sobre las Ciencias de la Computación y su oficio.

    OpenAIRE

    Martinez, María Cecilia; Echeveste, María Emilia

    2015-01-01

    Este artículo estudia la oferta de enseñanza en computación en 19 escuelas primarias y secundarias, públicas y privadas de la Provincia de Córdoba, Argentina. Posterior al desarrollo de un curso de introducción a la programación de 13 horas de duración a través de la creación de animaciones, analizamos los principales factores relacionados a la elección de las carreras en computación: representaciones de los estudiantes respecto al oficio de un especialista en computación, representaciones so...

  20. Detección del trastorno depresivo mayor en atención primaria. Una revisión

    OpenAIRE

    José Manuel Calvo-Gómez; Luis Eduardo Jaramillo-González

    2015-01-01

    Antecedentes. Distinguir entre los cambios que normalmente ocurren en el estado del ánimo y aquellos presentes en el trastorno depresivo no es una tarea fácil, por esta razón se han propuestos mecanismos e instrumentos para mejorar la detección de estos trastornos en pacientes de atención primaria. Objetivos. Evaluar si la detección sistemática rutinaria con instrumentos de tamizaje, con o sin sistemas de seguimiento y manejo integrado, es más efectiva que la atención usual para identificar p...

  1. Adquisición de vocabulario en inglés en un aula de Educación Primaria.

    OpenAIRE

    Sancho García, Elda

    2015-01-01

    Este trabajo hace referencia a la adquisición de vocabulario en una segunda lengua y consta de dos partes. En la primera nos ocupamos, de forma más general, de las teorías del aprendizaje e una segunda lengua, centrando nuestra atención en la adquisición de vocabulario y teniendo en cuenta las principales técnicas de enseñanza y aprendizaje del mismo. En la segunda parte se presentan un conjunto de actividades para enseñar vocabulario a los niños del primer curso de Educación Primaria relacio...

  2. Evaluación de competencias personales y sociales en contextos de educación primaria

    OpenAIRE

    Pizarro Ruiz, Juan Pablo

    2012-01-01

    El presente trabajo persigue el establecimiento de tipologías modales multivariadas de niños y niñas de segundo y tercer ciclo de Educación Primaria en función de las puntuaciones alcanzadas en los distintos factores del cuestionario de Personalidad Eficaz Ampliado. Se sigue la metodología de escenarios inacabados: pequeñas historias inacabadas acompañadas de una serie de cuestiones a las que los participantes deben dar respuesta. Estas son utilizadas como base para la redacción de los cuaren...

  3. RELACIÓN DE LA LECTOESCRITURA CON LOS PATRONES MOTRICES EN ALUMNOS DE EDUCACIÓN PRIMARIA

    OpenAIRE

    Del-Pozo-Sánchez, María Josefa

    2012-01-01

    En el presente trabajo se ha estudiado la posible relación entre los procesos de lectoescritura y motricidad y cómo estos influyen en el rendimiento académico. Para ello se ha tomado una muestra de 33 niños en educación primaria y se les ha evaluado con una batería de pruebas dirigida a valorar su motricidad y habilidades en lectura y escritura. Los resultados obtenidos muestran que si bien existe una relación moderada entre aspectos concretos de la motricidad y la lectura, no se puede ...

  4. Enseñanza, aprendizaje y evaluación en el Grado de Maestro de Primaria

    OpenAIRE

    Nortes Martínez Artero, Rosa; Nortes Checa, Andres

    2012-01-01

    Para conocer la relación entre enseñanza, aprendizaje y evaluación en el Grado de Maestro de Primaria, se aplicó una encuesta a los alumnos de 2.º del Grado de la universidad de Murcia, en donde se les pedía puntuaran numéricamente el Nivel de Enseñanza (NE), el Nivel de Aprendizaje (NA) y valoraran cada asignatura (VA), mientras que a los profesores se les solicitó la evaluación de la primera acta (CAL). Para cada asignatura se han tenido cuatro variables obt...

  5. Gioco, tecnologia e apprendimento: un esempio di approccio ludico per lo studio dell’arte contemporanea nella scuola primaria

    Directory of Open Access Journals (Sweden)

    Michela Nisdeo

    2014-09-01

    Full Text Available L’educazione all’arte contemporanea costituisce una dimensione spesso trascurata nelle scuole italiane. Il legame tra tecnologie digitali, dimensione ludica e arte può costituire un’interessante prospettiva da indagare. In questa direzione il contributo presenta un’esperienza relativa all’opera di Gino Marotta, un artista italiano, realizzata in una scuola primaria. L’aspetto che viene sottolineato è la relazione tra laboratori, attività online e giochi da un lato e risorse museali dall’altro.

  6. Detección del trastorno depresivo mayor en atención primaria. Una revisión

    Directory of Open Access Journals (Sweden)

    José Manuel Calvo-Gómez

    2015-07-01

    Full Text Available Antecedentes. Distinguir entre los cambios que normalmente ocurren en el estado del ánimo y aquellos presentes en el trastorno depresivo no es una tarea fácil, por esta razón se han propuestos mecanismos e instrumentos para mejorar la detección de estos trastornos en pacientes de atención primaria. Objetivos. Evaluar si la detección sistemática rutinaria con instrumentos de tamizaje, con o sin sistemas de seguimiento y manejo integrado, es más efectiva que la atención usual para identificar pacientes con depresión, facilitar su tratamiento, y mejorar los resultados clínicos en atención primaria. Materiales y métodos. Se llevó a cabo una búsqueda de estudios de casos y controles, cohortes y controlados aleatorizados, revisiones sistemáticas, y meta-análisis en las bases de datos MEDLINE, Cochrane, PsycINFO, y EMBASE desde enero de 1976 hasta el 30 de abril de 2013. Resultados. La evidencia mostró que muchos casos de depresión no son detectados. Los médicos de atención primaria (MAP logran tasas de detección del trastorno depresivo entre el 30% y 40%, sin utilizar herramientas adicionales para el diagnóstico como las escalas de una, dos y tres preguntas. Los pacientes con síntomas menos severos y más jóvenes son los menos detectados. Conclusiones. El tamizaje para depresión a nivel de atención primaria, con retroalimentación del resultado, puede incrementar el reconocimiento del trastorno por parte del MAP. Sin embargo, el efecto de la retroalimentación sobre el tratamiento y los resultados en cuanto a mejoría de los síntomas o remisión son muy pobres.

  7. Ciencias Experimentales en la Educación Infantil y en la Educación Primaria

    OpenAIRE

    Naves Pineda, Francisco Javier; Feliu Ortega, María José; Fernández-Lorenzo, Concepción

    2010-01-01

    Este curso engloba los conocimientos básicos que deben ser adquiridos por los alumnos en los grados de Magisterio en Educación Infantil y en Educación Primaria sobre las Ciencias Experimentales. De esta forma, se desarrollan temas que versan sobre la materia, la energía, la luz, los estados de agregación de la materia, etc, y se incluyen los conocimientos sobre el entorno que nos rodea desde un punto de vista físico y químico.

  8. Animación lectora para segundo de Primaria mediante diferentes géneros literarios y TIC’s

    OpenAIRE

    Urteaga-Zeberio, Izaro

    2014-01-01

    Este Trabajo Fin de Grado tiene como objetivo principal animar a alumnos del segundo curso de Educación Primaria a la lectura. Asimismo, hemos considerado otros objetivos como remarcar la importancia de la lectura, profundizar en el concepto de animación a la lectura, conocer programas informáticos para trabajar la lectura y escritura de cuentos y poemas y diseñar una propuesta de intervención. En cuanto a la metodología, hemos realizado una búsqueda de información a través de diferentes refe...

  9. El derecho humano a la atención primaria de salud en la lucha contra las enfermedades infecciosas

    OpenAIRE

    Allard Soto, Raúl

    2012-01-01

    La tesis doctoral tiene por objetivo central establecer la configuración básica del derecho humano a la atención primaria de salud en la lucha contra las enfermedades infecciosas, al que tiene derecho toda persona, para lo cual, durante el desarrollo de la tesis, se establecerán los elementos esenciales indisponibles que todo Estado se encuentra llamado a asegurar a su población, con el apoyo de la comunidad internacional y la cooperación económica y técnica de los demás Estados. La defini...

  10. Análisis de la Evaluación de los Deportes de Invasión en Primaria

    OpenAIRE

    Fernando Manuel Otero Saborido; África Calvo Lluch; José Antonio González Jurado

    2014-01-01

    El presente trabajo tiene por objeto analizar la evaluación docente de los deportes de invasión (DI) en Educación Primaria. Para ello se ha utilizado un diseño cuantitativo utilizando el cuestionario como instrumento tras una validación de contenido y un posterior análisis de la fiabilidad. Seis dimensiones sobre evaluación de los DI integraron el cuestionario final: objetivos a evaluar y frecuencia de utilización, instrumentos utilizados, dificultades de evaluación, distribución porcentual, ...

  11. Propuesta de Intervención para Alumnos con TEA en el Aula Ordinaria de Educación Primaria

    OpenAIRE

    Muñoz-Eizmendi, Irune

    2015-01-01

    Este trabajo presenta una propuesta de intervención para niños escolarizados en el Primer Curso de Educación Primaria diagnosticados con Trastorno del Espectro Autista (TEA). En ella, se desarrolla una adaptación de la Metodología TEACCH al aula ordinaria, empleada en educación especial, para responder a las necesidades educativas especiales derivadas de las características de estos alumnos. Para ello se examina en primer lugar, el término de Trastorno del Espectro Autista, sus antecedente...

  12. Proyecto educativo interdisciplinar de teatro para 5º y 6º de Educación Primaria

    OpenAIRE

    Munt-Pros, Mª. Noemí

    2015-01-01

    En este Trabajo de Fin de Grado se parte de la evolución histórica del teatro educativo y de la repercusión que ha tenido en diferentes épocas y contextos para analizar las contribuciones de su aplicación en el ámbito escolar. Diversas experiencias actuales refuerzan la idoneidad de esta metodología y sustentan la creación de un proyecto educativo para implantar el teatro en la escuela primaria. Así pues, el proyecto que se presenta propone el teatro para trabajar diferentes materias curricul...

  13. Los sistemas de apoyo en escuelas inclusivas de Educación Infantil y Primaria de la Comunidad Valenciana

    OpenAIRE

    Nadal Morant, María José

    2015-01-01

    En este trabajo se analiza la organización y el funcionamiento de los sistemas de apoyo actuales que se desarrollan en los centros de Educación Infantil y Primaria de la Comunidad Valenciana con el objetivo de determinar si favorecen o no la inclusión del alumnado con necesidades educativas especiales. Los objetivos específicos que se pretenden son: 1. Estudiar los diferentes elementos organizativos de los apoyos que intervienen en los centros para establecer cuál o cuáles de ellos favo...

  14. Concepciones previas de los estudiantes de Grado en Educación Primaria sobre la competencia digital de los escolares

    OpenAIRE

    Gutiérr ez-Cabello, Aingeru; Losada, Daniel; Correa, José Miguel

    2015-01-01

    La presente investigación tiene por objetivo estudiar las concepciones sobre las que parte los estudiantes de Grado en Educación Primaria sobre la competencia digital a lograr por su futuro alumnado. En la actualidad existen diversos autores que abogan por un desarrollo del constructo de la competencia digital basado en la multialfabetización. Por ello, a fin de recoger las diferentes creencias que subyacen al término se procedió a la construcción de una escal...

  15. Posibilidades didácticas de la ciencia experimental: la Meteorología en el aula de primaria.

    OpenAIRE

    Santín-Pérez, José Manuel

    2014-01-01

    El presente Trabajo de Fin de Grado, pretende estudiar las posibilidades del método científico experimental como herramienta pedagógica en el aula de primaria, tomando como punto de partida una ciencia experimental concreta: la Meteorología. Aplicar este método al aula permite introducir a los alumnos dentro de un contexto de análisis crítico de la realidad; contacto con el mundo físico; autonomía y responsabilidad; trabajo en equipo; y, especialmente, protagonizar el propio ap...

  16. Aprendizaje significativo mediante la creación de recursos didácticos para sexto de Primaria

    OpenAIRE

    González-Noda, Sara

    2014-01-01

    Este Trabajo de Fin de Grado consiste en una propuesta de intervención para un aula de sexto de Educación Primaria que pretende acercar al alumno a la aplicación práctica de las matemáticas mediante la manipulación y el trabajo en equipo. El trabajo comienza con un marco teórico, que trata aspectos relacionados con la legislación vigente, las características psicológicas de la etapa a la que va destinada la propuesta, el aprendizaje significativo, el trabajo colaborativo, el ap...

  17. La inteligencia intrapersonal en el aula de inglés de primaria: una medicina efectiva contra el fracaso escolar

    OpenAIRE

    García Gómez, Antonio

    2006-01-01

    La existencia de diferentes estilos de aprendizaje es un hecho probado en la bibliografía (Ehrman, 1996; Reid 1996). El presente estudio se propone, por un lado, presentar una breve reflexión sobre la problemática existente en nuestro sistema educativo y, por otro lado, analizar de manera crítica la teoría de las inteligencias múltiples propuesta por Howard Gardner (1983) y su aplicabilidad al aula de inglés de educación primaria. Nuestro estudio es el resultado de un estudio realiza...

  18. Resolución de problemas matemáticos de estructura aditiva en primero de primaria

    OpenAIRE

    Vergara-Urrea, Carla

    2016-01-01

    El objetivo del presente trabajo es proponer una didáctica diferente del razonamiento lógico-matemático empleado en la resolución de problemas en los niños de primero de primaria. Se propone una forma de trabajo en donde los alumnos son los protagonistas de su aprendizaje, utilizando para ello materiales manipulativos además de favorecer situaciones cotidianas en las que puedan desarrollar estrategias eficaces para resolver los problemas presentados. Para desarrollar esta propuesta de Proyect...

  19. Entrenamiento a Profesores de Preescolar y Primer Grado de Primaria, en el Uso de Estrategias de Enseñanza

    OpenAIRE

    Yolanda Guevara Benítez; Juan Pablo Rugerio Tapia; Ulises Delgado Sánchez; Ángela Hermosillo García

    2009-01-01

    La investigación prueba la efectividad de un programa de entrenamiento a profesores de tercer grado de preescolar y primero de primaria, para aplicar una serie de estrategias de enseñanza derivadas de la psicología conductual. Participaron profesoras de escuelas públicas de estrato sociocultural bajo. Antes y después del entrenamiento se filmó una hora de clase de cada profesora, filmaciones que sirvieron para registrar el uso de las estrategias educativas. El entrenamiento consistió en la en...

  20. El Inglés y las TIC: Propuesta de implantación del iPad en Primaria

    OpenAIRE

    Corella-Solera, Ana Cristina

    2014-01-01

    Tratándose el inglés y las TIC de dos elementos muy presentes la sociedad actual se considera imprescindible que los alumnos adquieran destrezas básicas en ellas. Este trabajo analiza la presencia de la lengua inglesa en el currículo de Educación Primaria, así como los métodos más utilizados para su enseñanza. Por otro lado se estudian recursos TIC útiles para la etapa que nos concierne y sus ventajas e inconvenientes para el alumnado, el profesor, el centro y el aprendizaje. Existiendo pr...