WorldWideScience

Sample records for aneta ozolina toms

  1. Aneta Fraczek-Szczypta

    Indian Academy of Sciences (India)

    Polysulphone composite membranes modified with two types of carbon additives as a potential material for bone tissue regeneration · ALICJA WEDEL-GRZENDA ANETA FRACZEK-SZCZYPTA MAURICIO TERRONES ANA LAURA ELÍAS MALGORZATA LEKKA ELZBIETA MENASZEK STANISLAW BLAZEWICZ.

  2. TOMS Absorbing Aerosol Index

    Data.gov (United States)

    Washington University St Louis — TOMS_AI_G is an aerosol related dataset derived from the Total Ozone Monitoring Satellite (TOMS) Sensor. The TOMS aerosol index arises from absorbing aerosols such...

  3. Researcher Interview: Tom Hudson

    Science.gov (United States)

    Tom Hudson, M.D., President and Scientific Director of the Ontario Institute for Cancer Research, describes the International Cancer Genome Consortium (ICGC), which brings together cancer genomic data and research from across the world.

  4. "Tom Byers: The New Colossus"

    DEFF Research Database (Denmark)

    Dalsgaard, Inger Hunnerup

    2013-01-01

    Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"......Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"...

  5. 75 FR 69470 - Tele Atlas North America, Inc., Currently Doing Business as Tom Tom Including Off-Site Workers...

    Science.gov (United States)

    2010-11-12

    ...,839B; TA-W-70,839C] Tele Atlas North America, Inc., Currently Doing Business as Tom Tom Including Off... Business as Tom Tom, Concord, MA; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Detroit, MI; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Redwood, CA; Amended...

  6. A Type System for Tom

    Directory of Open Access Journals (Sweden)

    Claude Kirchner

    2010-03-01

    Full Text Available Extending a given language with new dedicated features is a general and quite used approach to make the programming language more adapted to problems. Being closer to the application, this leads to less programming flaws and easier maintenance. But of course one would still like to perform program analysis on these kinds of extended languages, in particular type checking and inference. In this case one has to make the typing of the extended features compatible with the ones in the starting language. The Tom programming language is a typical example of such a situation as it consists of an extension of Java that adds pattern matching, more particularly associative pattern matching, and reduction strategies. This paper presents a type system with subtyping for Tom, that is compatible with Java's type system, and that performs both type checking and type inference. We propose an algorithm that checks if all patterns of a Tom program are well-typed. In addition, we propose an algorithm based on equality and subtyping constraints that infers types of variables occurring in a pattern. Both algorithms are exemplified and the proposed type system is showed to be sound and complete.

  7. Tom Ford Construction, LLC Information Sheet

    Science.gov (United States)

    Tom Ford Construction, LLC (the Company) is located in Brentwood, Tennessee. The settlement involves renovation activities conducted at a property constructed prior to 1978, located in Nashville, Tennessee.

  8. Updating the Micro-Tom TILLING platform.

    Science.gov (United States)

    Okabe, Yoshihiro; Ariizumi, Tohru; Ezura, Hiroshi

    2013-03-01

    The dwarf tomato variety Micro-Tom is regarded as a model system for functional genomics studies in tomato. Various tomato genomic tools in the genetic background of Micro-Tom have been established, such as mutant collections, genome information and a metabolomic database. Recent advances in tomato genome sequencing have brought about a significant need for reverse genetics tools that are accessible to the larger community, because a great number of gene sequences have become available from public databases. To meet the requests from the tomato research community, we have developed the Micro-Tom Targeting-Induced Local Lesions IN Genomes (TILLING) platform, which is comprised of more than 5000 EMS-mutagenized lines. The platform serves as a reverse genetics tool for efficiently identifying mutant alleles in parallel with the development of Micro-Tom mutant collections. The combination of Micro-Tom mutant libraries and the TILLING approach enables researchers to accelerate the isolation of desirable mutants for unraveling gene function or breeding. To upgrade the genomic tool of Micro-Tom, the development of a new mutagenized population is underway. In this paper, the current status of the Micro-Tom TILLING platform and its future prospects are described.

  9. Tomás Carrasquilla

    Directory of Open Access Journals (Sweden)

    Amalia Franco Castaño

    2014-01-01

    Full Text Available El reconocimiento de la obra del escritor antioqueño Tomás Carrasquilla, como una obra asociada al realismo y a los principios de interpretación de las relaciones sociales que esta propuesta implica permite que, desde la composición, el esquema de los personajes y los usos del lenguaje, pueda leerse una postura crítica que se distan - cia de las normas estéticas vigentes, para mostrar las contradicciones y los desacuerdos con los proyectos políticos e ideológicos que las respaldaban. Es así como Carrasquilla concreta en una novela como La Marquesa de Yolombó la expresión de una toma de posición que se respalda en la composición de un personaje femenino desde el cual expone no solo las implicaciones de una época de la sociedad colombiana sino, además, las posibilidades de comunicación con un presente que para el escritor amerita ser cuestionado y revelado desde la descomposición de la vida social y las contradicciones de los proyectos de liberación en Colombia.

  10. LILBID-mass spectrometry of the mitochondrial preprotein translocase TOM

    International Nuclear Information System (INIS)

    Mager, Frauke; Lintzel, Julia; Nussberger, Stephan; Sokolova, Lucie; Brutschy, Bernhard

    2010-01-01

    In the present work we applied a novel mass spectrometry method termed laser-induced liquid bead ion desorption mass spectrometry (LILBID-MS) to the outer mitochondrial membrane protein translocon TOM to analyze its subunit composition and stoichiometry. With TOM core complex, purified at high pH, we demonstrate that a TOM core complex of Neurospora crassa is composed of at least two Tom40 and Tom22 molecules, respectively, and more than five small Tom subunits between 5.5 and 6.4 kDa. We show that the multiprotein complex has a total molecular mass higher than 170 depending on the number of Tom5, Tom6 and Tom7 molecules bound.

  11. LILBID-mass spectrometry of the mitochondrial preprotein translocase TOM

    Science.gov (United States)

    Mager, Frauke; Sokolova, Lucie; Lintzel, Julia; Brutschy, Bernhard; Nussberger, Stephan

    2010-11-01

    In the present work we applied a novel mass spectrometry method termed laser-induced liquid bead ion desorption mass spectrometry (LILBID-MS) to the outer mitochondrial membrane protein translocon TOM to analyze its subunit composition and stoichiometry. With TOM core complex, purified at high pH, we demonstrate that a TOM core complex of Neurospora crassa is composed of at least two Tom40 and Tom22 molecules, respectively, and more than five small Tom subunits between 5.5 and 6.4 kDa. We show that the multiprotein complex has a total molecular mass higher than 170 depending on the number of Tom5, Tom6 and Tom7 molecules bound.

  12. Ionizing radiation environment for the TOMS mission

    Science.gov (United States)

    Lauriente, M.; Maloy, J. O.; Vampola, A. L.

    1992-01-01

    The Total Ozone Mapping Spectrometer (TOMS) will fly on several different spacecraft, each having an orbit which is approximately polar and 800-980 km in altitude. A description is given of the computer-based tools used for characterizing the spacecraft interactions with the ionizing radiation environment in orbit and the susceptibility requirements for ionizing radiation compatibility. The peak flux from the model was used to derive the expected radiation-induced noise in the South Atlantic Anomaly for the new TOMS instruments intended to fly on Advanced Earth Observatory System and Earth Probe.

  13. The Unseen Déjà-Vu: From Erkki Huhtamo's Topoi to Ken Jacobs' Remakes: Commentary to Edwin Carels "Revisiting Tom Tom: Performative anamnesis and autonomous vision in Ken Jacobs' appropriations of Tom Tom the Piper's Son".

    Science.gov (United States)

    Strauven, Wanda

    2018-01-01

    This commentary on Edwin Carels' essay "Revisiting Tom Tom : Performative anamnesis and autonomous vision in Ken Jacobs' appropriations of Tom Tom the Piper's Son " broadens up the media-archaeological framework in which Carels places his text. Notions such as Huhtamo's topos and Zielinski's "deep time" are brought into the discussion in order to point out the difficulty to see what there is to see and to question the position of the viewer in front of experimental films like Tom Tom the Piper's Son and its remakes.

  14. Tom Brown appointed Dean of Students

    OpenAIRE

    Williams, Meghan

    2007-01-01

    James Thomas "Tom" Brown, former senior associate dean of the Dean of Students office, has been appointed as the Dean of Students. The Dean of Students office is responsible for the coordination of student advocacy, new student orientation and parent programs, and responding to student emergencies in collaboration with Judicial Affairs, Residence Life, Cook Counseling Center, Schiffert Health Center, and other departments and agencies.

  15. STS-98 Crew Interview: Tom Jones

    Science.gov (United States)

    2001-01-01

    The STS-98 Mission Specialist Tom Jones is seen being interviewed. He answers questions about his inspiration to become an astronaut, his career path, and his training. He gives details on the mission's goals and significance, and the payload and hardware it brings to the International Space Station (ISS). Mr. Jones discusses his role in the mission's spacewalks and activities.

  16. Tom Olaf Urb / intervjueerinud Siim Õ. Ilves

    Index Scriptorium Estoniae

    Urb, Tom Olaf, 1985-

    2016-01-01

    Muusik, produtsent, kirjanik ja näitleja Tom-Olaf Urb, lavanimega Reket, arutleb disaini teemal ja nimetab kümme disainieset, mis teda elus köitnud on. Eesti Hip-Hop auhindade jagamisel valiti Reketi "Tuule tee" 2015.a. parimaks kodumaiseks hip-hop albumiks

  17. Tropospheric Ozone from the TOMS TDOT (TOMS-Direct-Ozone-in-Troposphere) Technique During SAFARI-2000

    Science.gov (United States)

    Stone, J. B.; Thompson, A. M.; Frolov, A. D.; Hudson, R. D.; Bhartia, P. K. (Technical Monitor)

    2002-01-01

    There are a number of published residual-type methods for deriving tropospheric ozone from TOMS (Total Ozone Mapping Spectrometer). The basic concept of these methods is that within a zone of constant stratospheric ozone, the tropospheric ozone column can be computed by subtracting stratospheric ozone from the TOMS Level 2 total ozone column, We used the modified-residual method for retrieving tropospheric ozone during SAFARI-2000 and found disagreements with in-situ ozone data over Africa in September 2000. Using the newly developed TDOT (TOMS-Direct-Ozone-in-Troposphere) method that uses TOMS radiances and a modified lookup table based on actual profiles during high ozone pollution periods, new maps were prepared and found to compare better to soundings over Lusaka, Zambia (15.5 S, 28 E), Nairobi and several African cities where MOZAIC aircraft operated in September 2000. The TDOT technique and comparisons are described in detail.

  18. Clean Coal Power at Toms Creek

    International Nuclear Information System (INIS)

    Schmid, M.R.

    1993-01-01

    On October 20, 1992 the US Department of Energy (DOE), through the Morgantown Energy Technology Center, entered into Cooperative Agreement DE-FC-21-93MC92444 with TAMCO Power Partners to implement the Toms Creek Integrated Gasification Combined - Cycle Demonstration Project. The process design is proceeding as scheduled, and a draft Environmental Information Volume has been produced. The overall project schedule, however, may have to be adjusted when the Power Sales Agreement has been finalized

  19. Social versus Intrapersonal ToM: Social ToM Is a Cognitive Strength for Low- and Middle-SES Children

    Science.gov (United States)

    Lucariello, Joan M.; Durand, Tina M.; Yarnell, Lisa

    2007-01-01

    Metarepresentational theory of mind (ToM) was studied in middle- and low-SES five- and six-year-olds. Two aspects of ToM were distinguished. Reasoning about one's own mental states (Intrapersonal ToM) was assessed in the intrapersonal ToM task condition and reasoning about others' mental states (Social ToM) was assessed in the social ToM task…

  20. Hydrodynamic Aspects of the Toms Effect

    Science.gov (United States)

    Strel‧nikova, S. A.; Tkachenko, G. V.; Uryukov, B. A.

    2015-11-01

    The physicomathematical model of migration of polymers in a liquid turbulent flow in a pipe is based on a comparison of forces transverse to the motion of the mainstream flow: the Saffman, Magnus, and turbophoresis forces. It has been shown that the polymer particles are grouped near a certain boundary within the limits of the boundary layer. On this basis, the authors have made assumptions on the mechanism of suppression of turbulent pulsations and decrease in the viscous friction near the wall, which makes up the Toms effect. The proposed model satisfies, at least, qualitatively, various actually observed manifestations of the effect.

  1. Tropical easterly jet located using TOMS data

    Science.gov (United States)

    Bolhofer, William C.

    1987-01-01

    The formative stages of the onset of the 1979 southwest monsoon was marked by a WNW-ESE oriented band of marine convection over the South Arabian Sea. This convection was first observed on June 10, 1979 using satellite cloud imagery. The marine convection appeared during a major acceleration of the upper troposphere easterly wind field. A composite vertical meridional cross-section of upper level winds for June 11, revealed the core of the Tropical Easterly Jet (TEJ) at 115 mb, 9.5 deg N. Time analysis of the upper level wind field over the Tropical Wind Observing Ship (TWOS) polygon show a lowering of both the pressure level of maximum wind and tropopause level with acceleration of the upper level easterlies. The tropopause was as much as 20 mb lower on the equatorial side of the TEJ. Streamline analysis of the maximum observed easterly winds over India did not reveal the horizontal position of the TEJ. Careful analysis of Total Ozone Mapping Spectrometer (TOMS) data for June 11, 1979 showed relatively high values of ozone south of India. It was observed that the latitudinal position of the TEJ on June 11, at approximately 70 deg E coincided with the northern edge of relatively high ozone values. Using this as a reference, the TEJ core was identified as far as NE Bay of Bengal (the limits of the available TOMS data).

  2. Longitudinal Theory of Mind (ToM) Development From Preschool to Adolescence With and Without ToM Delay.

    Science.gov (United States)

    Peterson, Candida C; Wellman, Henry M

    2018-04-16

    Longitudinal tracking of 107 three- to-thirteen-year-olds in a cross-sequential design showed a 6-step theory of mind (ToM) sequence identified by a few past cross-sectional studies validly depicted longitudinal ToM development from early to middle childhood for typically developing (TD) children and those with ToM delays owing to deafness or autism. Substantively, all groups showed ToM progress throughout middle childhood. Atypical development was more extended and began and ended at lower levels than for TD children. Yet most children in all groups progressed over the study's mean 1.5 years. Findings help resolve theoretical debates about ToM development for children with and without delay and gain strength and weight via their applicability to three disparate groups varying in ToM timing and sequencing. © 2018 Society for Research in Child Development.

  3. Testicular morphometry and sperm reserves of local turkey toms fed ...

    African Journals Online (AJOL)

    The morphometry and sperm reserves of the testis, epididymis and vas deferens of three groups (n=5/ group) of sexually active adult local turkey toms fed isocaloric diet with varying levels (12 %, 16 %, 20 %) of protein were studied for sixteen weeks. The weights of the toms before treatment were between 3.5 – 4.5 kg, while ...

  4. 78 FR 12307 - Taylor, G. Tom; Notice of Filing

    Science.gov (United States)

    2013-02-22

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-5705-001] Taylor, G. Tom; Notice of Filing Take notice that on February 14, 2013, G. Tom Taylor filed an application to hold interlocking positions pursuant to section 305(b) of the Federal Power Act, 16 U.S.C. 825d(b), Part 45 of the...

  5. TOM9.2 Is a Calmodulin-Binding Protein Critical for TOM Complex Assembly but Not for Mitochondrial Protein Import in Arabidopsis thaliana.

    Science.gov (United States)

    Parvin, Nargis; Carrie, Chris; Pabst, Isabelle; Läßer, Antonia; Laha, Debabrata; Paul, Melanie V; Geigenberger, Peter; Heermann, Ralf; Jung, Kirsten; Vothknecht, Ute C; Chigri, Fatima

    2017-04-03

    The translocon on the outer membrane of mitochondria (TOM) facilitates the import of nuclear-encoded proteins. The principal machinery of mitochondrial protein transport seems conserved in eukaryotes; however, divergence in the composition and structure of TOM components has been observed between mammals, yeast, and plants. TOM9, the plant homolog of yeast Tom22, is significantly smaller due to a truncation in the cytosolic receptor domain, and its precise function is not understood. Here we provide evidence showing that TOM9.2 from Arabidopsis thaliana is involved in the formation of mature TOM complex, most likely by influencing the assembly of the pore-forming subunit TOM40. Dexamethasone-induced RNAi gene silencing of TOM9.2 results in a severe reduction in the mature TOM complex, and the assembly of newly imported TOM40 into the complex is impaired. Nevertheless, mutant plants are fully viable and no obvious downstream effects of the loss of TOM complex, i.e., on mitochondrial import capacity, were observed. Furthermore, we found that TOM9.2 can bind calmodulin (CaM) in vitro and that CaM impairs the assembly of TOM complex in the isolated wild-type mitochondria, suggesting a regulatory role of TOM9.2 and a possible integration of TOM assembly into the cellular calcium signaling network. Copyright © 2017 The Author. Published by Elsevier Inc. All rights reserved.

  6. Annual Quality Assurance Conference Files by Tom Mancuso

    Science.gov (United States)

    25th Annual Quality Assurance Conference. Abstract: Learn about the NEW EPA Method 325b for Refinery Fence Line Monitoring and TO-17 Extended for Soil Gas by Tom Mancuso and Abstract: Success Using Alternate Carrier Gases for Volatile Methods

  7. Tom Russell: "Õpetajakoolitust tuleks alustada praktikast" / Liisa Lumiste

    Index Scriptorium Estoniae

    Lumiste, Liisa

    2013-01-01

    Eduko programmi raames Tallinna Ülikoolis toimunud avalikul loengul rääkis Kanada kasvatusteadlane Tom Russell praktika tähtsusest õpetajakoolituses ja viis läbi meistriklassi õpetajakoolituse õppejõududele

  8. Compare and analyse marketing strategies using consumer focused studies. The case of TomTom vs. Garmin

    OpenAIRE

    Stefanova, Antonia

    2014-01-01

    The following dissertation paper focuses on a central research question that is to compare and appraise strategic marketing activities of a first mover navigation organisation, TomTom B.V., to its most prominent competitor Garmin Ltd, a successful follower. The intense situation in the global positioning systems market provides a great possibility of investigating the two giant organisations' internal environment, competitive environment and customers' purchase behaviour. In this regard, mark...

  9. Cryo-EM Structure of the TOM Core Complex from Neurospora crassa.

    Science.gov (United States)

    Bausewein, Thomas; Mills, Deryck J; Langer, Julian D; Nitschke, Beate; Nussberger, Stephan; Kühlbrandt, Werner

    2017-08-10

    The TOM complex is the main entry gate for protein precursors from the cytosol into mitochondria. We have determined the structure of the TOM core complex by cryoelectron microscopy (cryo-EM). The complex is a 148 kDa symmetrical dimer of ten membrane protein subunits that create a shallow funnel on the cytoplasmic membrane surface. In the core of the dimer, the β-barrels of the Tom40 pore form two identical preprotein conduits. Each Tom40 pore is surrounded by the transmembrane segments of the α-helical subunits Tom5, Tom6, and Tom7. Tom22, the central preprotein receptor, connects the two Tom40 pores at the dimer interface. Our structure offers detailed insights into the molecular architecture of the mitochondrial preprotein import machinery. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Shallow ground-water conditions, Tom Green County, Texas

    Science.gov (United States)

    Lee, J.N.

    1986-01-01

    Most of the water needs of Tom Green County, Texas, are supplied by ground water; however, the city of San Angelo is supplied by surface water. Groundwater withdrawals during 1980 (latest year for which data are available) in Tom Green County totaled about 15,300 acre-feet, all derived from shallow aquifers. Shallow aquifers in this report refer to the ground-water system generally less than 400 feet deep that contains water with less than a 10,000 milligrams per liter concentration of dissolved solids; aquifers comprising this system include: The Leona, Comanche Peak, Trinity, Blaine, San Angelo, Choza, Bullwagon, Vale, Standpipe, and Arroyo aquifers.

  11. Single molecule tracking fluorescence microscopy in mitochondria reveals highly dynamic but confined movement of Tom40

    Science.gov (United States)

    Kuzmenko, Anton; Tankov, Stoyan; English, Brian P.; Tarassov, Ivan; Tenson, Tanel; Kamenski, Piotr; Elf, Johan; Hauryliuk, Vasili

    2011-12-01

    Tom40 is an integral protein of the mitochondrial outer membrane, which as the central component of the Translocase of the Outer Membrane (TOM) complex forms a channel for protein import. We characterize the diffusion properties of individual Tom40 molecules fused to the photoconvertable fluorescent protein Dendra2 with millisecond temporal resolution. By imaging individual Tom40 molecules in intact isolated yeast mitochondria using photoactivated localization microscopy with sub-diffraction limited spatial precision, we demonstrate that Tom40 movement in the outer mitochondrial membrane is highly dynamic but confined in nature, suggesting anchoring of the TOM complex as a whole.

  12. Isepäine iseõppija Tom Dixon

    Index Scriptorium Estoniae

    2007-01-01

    Inglise disainerist Tom Dixonist (sünd. 1959) ja tema loomingust. 1998. aastast UK disainistuudio juht mööblifirma Habitat juures, mööblitööstuse Artek loominguline direktor. Aprillis 2007 esines Milano mööblimessil vaskvalgustite kollektsiooniga ja Triennale pargis koostöös Shigeru Baniga Arteki paviljoniga

  13. Culture of the Tomato Micro-Tom Cultivar in Greenhouse.

    Science.gov (United States)

    Rothan, Christophe; Just, Daniel; Fernandez, Lucie; Atienza, Isabelle; Ballias, Patricia; Lemaire-Chamley, Martine

    2016-01-01

    Micro-Tom tomato cultivar is particularly adapted to the development of genomic approaches in tomato. Here, we describe the culture of this plant in greenhouse, including climate regulation, seed sowing and watering, vegetative development, plant maintenance, including treatment of phytosanitary problems, and reproductive development.

  14. TOMS/EP UV Reflectivity Daily and Monthly Zonal Means V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/EP UV Reflectivity Daily and Monthly Zonal Means Version 8 data in ASCII format. (The shortname for this Level-3 Earth Probe TOMS...

  15. Reducing the Language Content in ToM Tests: A Developmental Scale

    Science.gov (United States)

    Burnel, Morgane; Perrone-Bertolotti, Marcela; Reboul, Anne; Baciu, Monica; Durrleman, Stephanie

    2018-01-01

    The goal of the current study was to statistically evaluate the reliable scalability of a set of tasks designed to assess Theory of Mind (ToM) without language as a confounding variable. This tool might be useful to study ToM in populations where language is impaired or to study links between language and ToM. Low verbal versions of the ToM tasks…

  16. 77 FR 39406 - Safety Zone; Tom Graves Memorial Fireworks, Port Bay, Wolcott, NY

    Science.gov (United States)

    2012-07-03

    ...-AA00 Safety Zone; Tom Graves Memorial Fireworks, Port Bay, Wolcott, NY AGENCY: Coast Guard, DHS. ACTION..., NY. This safety zone is intended to restrict vessels from a portion of Port Bay during the Tom Graves... necessary to ensure the safety of spectators and vessels during the Tom Graves Memorial Fireworks. This zone...

  17. Measuring Theory of Mind in Children. Psychometric Properties of the ToM Storybooks

    NARCIS (Netherlands)

    Blijd-Hoogewys, E. M. A.; van Geert, P. L. C.; Serra, M.; Minderaa, R. B.

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various

  18. Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins.

    Science.gov (United States)

    Stojanovski, Diana; Guiard, Bernard; Kozjak-Pavlovic, Vera; Pfanner, Nikolaus; Meisinger, Chris

    2007-12-03

    The mitochondrial outer membrane contains two preprotein translocases: the general translocase of outer membrane (TOM) and the beta-barrel-specific sorting and assembly machinery (SAM). TOM functions as the central entry gate for nuclear-encoded proteins. The channel-forming Tom40 is a beta-barrel protein, whereas all Tom receptors and small Tom proteins are membrane anchored by a transmembrane alpha-helical segment in their N- or C-terminal portion. Synthesis of Tom precursors takes place in the cytosol, and their import occurs via preexisting TOM complexes. The precursor of Tom40 is then transferred to SAM for membrane insertion and assembly. Unexpectedly, we find that the biogenesis of alpha-helical Tom proteins with a membrane anchor in the C-terminal portion is SAM dependent. Each SAM protein is necessary for efficient membrane integration of the receptor Tom22, whereas assembly of the small Tom proteins depends on Sam37. Thus, the substrate specificity of SAM is not restricted to beta-barrel proteins but also includes the majority of alpha-helical Tom proteins.

  19. Measuring Theory of Mind in Children. Psychometric Properties of the ToM Storybooks

    NARCIS (Netherlands)

    Blijd-Hoogewys, E. M. A.; van Geert, P. L. C.; Serra, M.; Minderaa, R. B.

    2008-01-01

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various

  20. Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors.

    Science.gov (United States)

    Becker, Thomas; Pfannschmidt, Sylvia; Guiard, Bernard; Stojanovski, Diana; Milenkovic, Dusanka; Kutik, Stephan; Pfanner, Nikolaus; Meisinger, Chris; Wiedemann, Nils

    2008-01-04

    The translocase of the outer membrane (TOM complex) is the central entry gate for nuclear-encoded mitochondrial precursor proteins. All Tom proteins are also encoded by nuclear genes and synthesized as precursors in the cytosol. The channel-forming beta-barrel protein Tom40 is targeted to mitochondria via Tom receptors and inserted into the outer membrane by the sorting and assembly machinery (SAM complex). A further outer membrane protein, Mim1, plays a less defined role in assembly of Tom40 into the TOM complex. The three receptors Tom20, Tom22, and Tom70 are anchored in the outer membrane by a single transmembrane alpha-helix, located at the N terminus in the case of Tom20 and Tom70 (signal-anchored) or in the C-terminal portion in the case of Tom22 (tail-anchored). Insertion of the precursor of Tom22 into the outer membrane requires pre-existing Tom receptors while the import pathway of the precursors of Tom20 and Tom70 is only poorly understood. We report that Mim1 is required for efficient membrane insertion and assembly of Tom20 and Tom70, but not Tom22. We show that Mim1 associates with SAM(core) components to a large SAM complex, explaining its role in late steps of the assembly pathway of Tom40. We conclude that Mim1 is not only required for biogenesis of the beta-barrel protein Tom40 but also for membrane insertion and assembly of signal-anchored Tom receptors. Thus, Mim1 plays an important role in the efficient assembly of the mitochondrial TOM complex.

  1. Design, fabrication and performance of the 10-in TOM HPD

    CERN Document Server

    Braem, André; Joram, C; Séguinot, Jacques; Weilhammer, P; Giunta, M; Malakhov, N; Menzione, A; Pegna, R; Piccioli, A; Raffaelli, F; Sartori, G

    2004-01-01

    The first sealed TOM Hybrid Photon Detector (HPD) with 10-in. diameter has been fabricated and successfully tested at CERN. This HPD has a spherical entrance window and a bialkali photocathode. The fountain focusing optics produces a demagnified image (D = 4) on the round segmented silicon sensor. The signals of the 2048 cells are read out through analog front-end electronics encapsulated in the vacuum envelope. We report on the design, fabrication technique and the experimental results obtained with laboratory test benches. The large TOM HPD is a prototype tube developed for the CLUE cosmic ray experiment. The final tubes, now under development, will be equipped with a solar-blind Rb//2Te photocathode and self triggering front-end electronics.

  2. Highlights of TOMS Version 9 Total Ozone Algorithm

    Science.gov (United States)

    Bhartia, Pawan; Haffner, David

    2012-01-01

    The fundamental basis of TOMS total ozone algorithm was developed some 45 years ago by Dave and Mateer. It was designed to estimate total ozone from satellite measurements of the backscattered UV radiances at few discrete wavelengths in the Huggins ozone absorption band (310-340 nm). Over the years, as the need for higher accuracy in measuring total ozone from space has increased, several improvements to the basic algorithms have been made. They include: better correction for the effects of aerosols and clouds, an improved method to account for the variation in shape of ozone profiles with season, latitude, and total ozone, and a multi-wavelength correction for remaining profile shape errors. These improvements have made it possible to retrieve total ozone with just 3 spectral channels of moderate spectral resolution (approx. 1 nm) with accuracy comparable to state-of-the-art spectral fitting algorithms like DOAS that require high spectral resolution measurements at large number of wavelengths. One of the deficiencies of the TOMS algorithm has been that it doesn't provide an error estimate. This is a particular problem in high latitudes when the profile shape errors become significant and vary with latitude, season, total ozone, and instrument viewing geometry. The primary objective of the TOMS V9 algorithm is to account for these effects in estimating the error bars. This is done by a straightforward implementation of the Rodgers optimum estimation method using a priori ozone profiles and their error covariances matrices constructed using Aura MLS and ozonesonde data. The algorithm produces a vertical ozone profile that contains 1-2.5 pieces of information (degrees of freedom of signal) depending upon solar zenith angle (SZA). The profile is integrated to obtain the total column. We provide information that shows the altitude range in which the profile is best determined by the measurements. One can use this information in data assimilation and analysis. A side

  3. Design, fabrication and performance of the 10-in. TOM HPD

    International Nuclear Information System (INIS)

    Braem, A.; Chesi, E.; Joram, C.; Seguinot, J.; Weilhammer, P.; Giunta, M.; Malakhov, N.; Menzione, A.; Pegna, R.; Piccioli, A.; Raffaelli, F.; Sartori, G.

    2004-01-01

    The first sealed TOM Hybrid Photon Detector (HPD) with 10-in. diameter has been fabricated and successfully tested at CERN. This HPD has a spherical entrance window and a bialkali photocathode. The fountain focusing optics produces a demagnified image (D=4) on the round segmented silicon sensor. The signals of the 2048 cells are read out through analog front-end electronics encapsulated in the vacuum envelope. We report on the design, fabrication technique and the experimental results obtained with laboratory test benches. The large TOM HPD is a prototype tube developed for the CLUE cosmic ray experiment. The final tubes, now under development, will be equipped with a solar-blind Rb 2 Te photocathode and self triggering front-end electronics

  4. Tom Bissel, Voglia di vincere/Extra Lives

    Directory of Open Access Journals (Sweden)

    Ambra Agnoletto

    2013-03-01

    Full Text Available Leggere il libro di Tom Bissell Extra lives: Why Video Games Matter, tradotto in Italia con il titolo Voglia di vincere, è stata un’impresa. L’impresa di qualcuno abituato a muoversi in ambito cinematografico e musicale, ma che affronta con l’entusiasmo e le incertezze del neofita i videogames e tutto ciò che riguarda la sfera videoludica, nei suoi aspetti creativi, estetici, di design e meccanica di gioco.

  5. Derivation of Tropospheric Ozone Climatology and Trends from TOMS Data

    Science.gov (United States)

    Newchurch, Michael J.; McPeters, Rich; Logan, Jennifer; Kim, Jae-Hwan

    2002-01-01

    This research addresses the following three objectives: (1) Derive tropospheric ozone columns from the TOMS instruments by computing the difference between total-ozone columns over cloudy areas and over clear areas in the tropics; (2) Compute secular trends in Nimbus-7 derived tropospheric Ozone column amounts and associated potential trends in the decadal-scale tropical cloud climatology; (3) Explain the occurrence of anomalously high ozone retrievals over high ice clouds.

  6. Preliminary X-ray crystallographic studies of yeast mitochondrial protein Tom70p

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Yunkun [Department of Cell Biology, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States); McCombs, Debbie; Nagy, Lisa; DeLucas, Lawrence [Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States); Sha, Bingdong, E-mail: bdsha@uab.edu [Department of Cell Biology, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States)

    2006-03-01

    Tom70p is an important translocase of the outer membrane complex member and a major surface receptor of the protein-translocation machinery in the outer mitochondrial membrane. To investigate the mechanism by which Tom70p functions to deliver the mitochondrial protein precursors, the cytosolic fragment of yeast Tom70p (cTom70p) has been crystallized. Protein translocations across mitochondrial membranes play critical roles in mitochondrion biogenesis. Protein transport from the cell cytosol to the mitochondrial matrix is carried out by the translocase of the outer membrane (TOM) complex and the translocase of the inner membrane (TIM) complexes. Tom70p is an important TOM-complex member and a major surface receptor of the protein-translocation machinery in the outer mitochondrial membrane. To investigate the mechanism by which Tom70p functions to deliver the mitochondrial protein precursors, the cytosolic fragment of yeast Tom70p (cTom70p) was crystallized. The crystals diffract to 3.2 Å using a synchrotron X-ray source and belong to space group P2{sub 1}, with unit-cell parameters a = 44.89, b = 168.78, c = 83.41 Å, α = 90.00, β = 102.74, γ = 90.00°. There are two Tom70p molecules in one asymmetric unit, which corresponds to a solvent content of approximately 51%. Structure determination by MAD methods is under way.

  7. Music and subversion in Tom Stoppard's rock 'n'roll

    OpenAIRE

    Matos, Susana Isabel Mendes de

    2013-01-01

    This dissertation aims at analysing music as a form of subversion in Tom Stoppard’s play Rock ‘N’ Roll. After a short summary of Stoppard’s career, the bands and songs chosen by him are analysed from the perspective of subversion against censorship and totalitarian regimes, relating them to the plot. The dissertation also focuses on the specific case of the Czech band the Plastic People of the Universe and its importance to the history of Czechoslovakia between 1968 and 1990. O presente tr...

  8. Novel TPR-containing subunit of TOM complex functions as cytosolic receptor for Entamoeba mitosomal transport.

    Science.gov (United States)

    Makiuchi, Takashi; Mi-ichi, Fumika; Nakada-Tsukui, Kumiko; Nozaki, Tomoyoshi

    2013-01-01

    Under anaerobic environments, the mitochondria have undergone remarkable reduction and transformation into highly reduced structures, referred as mitochondrion-related organelles (MROs), which include mitosomes and hydrogenosomes. In agreement with the concept of reductive evolution, mitosomes of Entamoeba histolytica lack most of the components of the TOM (translocase of the outer mitochondrial membrane) complex, which is required for the targeting and membrane translocation of preproteins into the canonical aerobic mitochondria. Here we showed, in E. histolytica mitosomes, the presence of a 600-kDa TOM complex composed of Tom40, a conserved pore-forming subunit, and Tom60, a novel lineage-specific receptor protein. Tom60, containing multiple tetratricopeptide repeats, is localized to the mitosomal outer membrane and the cytosol, and serves as a receptor of both mitosomal matrix and membrane preproteins. Our data indicate that Entamoeba has invented a novel lineage-specific shuttle receptor of the TOM complex as a consequence of adaptation to an anaerobic environment.

  9. Meta-analysis of Theory of Mind (ToM) impairment in bipolar disorder.

    Science.gov (United States)

    Bora, E; Bartholomeusz, C; Pantelis, C

    2016-01-01

    Theory of mind (ToM) dysfunction is prominent in a number of psychiatric disorders, in particular, autism and schizophrenia, and can play a significant role in poor functioning. There is now emerging evidence suggesting that ToM abilities are also impaired in bipolar disorder (BP); however, the relationship between ToM deficits and mood state is not clear. We conducted a meta-analysis of ToM studies in BP. Thirty-four studies comparing 1214 patients with BP and 1097 healthy controls were included. BP groups included remitted (18 samples, 545 BP patients), subsyndromal (12 samples, 510 BP patients), and acute (manic and/or depressed) (10 samples, 159 BP patients) patients. ToM performance was significantly impaired in BP compared to controls. This impairment was evident across different types of ToM tasks (including affective/cognitive and verbal/visual) and was also evident in strictly euthymic patients with BP (d = 0.50). There were no significant differences between remitted and subsyndromal samples. However, ToM deficit was significantly more severe during acute episodes (d = 1.23). ToM impairment was significantly associated with neurocognitive and particularly with manic symptoms. Significant but modest sized ToM dysfunction is evident in remitted and subsyndromal BP. Acute episodes are associated with more robust ToM deficits. Exacerbation of ToM deficits may contribute to the more significant interpersonal problems observed in patients with acute or subsyndromal manic symptoms. There is a need for longitudinal studies comparing the developmental trajectory of ToM deficits across the course of the illness.

  10. Cognitive, affective, and conative theory of mind (ToM) in children with traumatic brain injury.

    Science.gov (United States)

    Dennis, Maureen; Simic, Nevena; Bigler, Erin D; Abildskov, Tracy; Agostino, Alba; Taylor, H Gerry; Rubin, Kenneth; Vannatta, Kathryn; Gerhardt, Cynthia A; Stancin, Terry; Yeates, Keith Owen

    2013-07-01

    We studied three forms of dyadic communication involving theory of mind (ToM) in 82 children with traumatic brain injury (TBI) and 61 children with orthopedic injury (OI): Cognitive (concerned with false belief), Affective (concerned with expressing socially deceptive facial expressions), and Conative (concerned with influencing another's thoughts or feelings). We analyzed the pattern of brain lesions in the TBI group and conducted voxel-based morphometry for all participants in five large-scale functional brain networks, and related lesion and volumetric data to ToM outcomes. Children with TBI exhibited difficulty with Cognitive, Affective, and Conative ToM. The perturbation threshold for Cognitive ToM is higher than that for Affective and Conative ToM, in that Severe TBI disturbs Cognitive ToM but even Mild-Moderate TBI disrupt Affective and Conative ToM. Childhood TBI was associated with damage to all five large-scale brain networks. Lesions in the Mirror Neuron Empathy network predicted lower Conative ToM involving ironic criticism and empathic praise. Conative ToM was significantly and positively related to the package of Default Mode, Central Executive, and Mirror Neuron Empathy networks and, more specifically, to two hubs of the Default Mode Network, the posterior cingulate/retrosplenial cortex and the hippocampal formation, including entorhinal cortex and parahippocampal cortex. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Training older adults on Theory of Mind (ToM): transfer on metamemory.

    Science.gov (United States)

    Lecce, Serena; Bottiroli, Sara; Bianco, Federica; Rosi, Alessia; Cavallini, Elena

    2015-01-01

    Research on aging has shown a significant decline in ToM after 65 years of age. Despite these age-related difficulties, no study has yet investigated the possibility to improve ToM in older adults. To address this gap we tested the efficacy of a conversation-based ToM training with age-appropriate ToM tasks and its transfer effects on metamemory. We examined 72 older adults (Mage=67.61 years, SD=6.39 years) assigned to three training conditions: a ToM training, a physical-conversation training and a social-contact group. All participants took part in two 2-h testing and to two 2-h training sessions. Results showed that after the intervention, older adults in the ToM training group improved their mental states' understanding significantly more than participants in the physical-conversation training and in the social-contact groups. Crucially, the positive effect of the ToM intervention generalized to metamemory knowledge. This is the first study investigating the efficacy of a ToM training and its transfer effect on metacognition in older adults. From a theoretical point of view, it supports the relation between ToM and metamemory. Practical implications of these data are discussed. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  12. Voyeuristi alla finestra: Peeping Tom, dalla leggenda al cinema

    Directory of Open Access Journals (Sweden)

    Laura Staiano

    2015-01-01

    Full Text Available This essay deals with voyeuristic attitudes and ʹscopic powerʹ, i.e. the power to gaze at forbidden things and people without being seen. Indeed, its object par excellence coincides with female nakedness, while its subject is an invisible masculinity, which takes delight in looking. The paper is based on a study of the Anglo-Saxon legend of Lady Godiva and it is strictly connected with the subject of my dissertation in progress – metaphorical and physical blindness in 18th century French literature (since several voyeurs got blind because of their instincts and desires. Lady Godiva’s voyeur, called Peeping Tom, is struck blind for having looked out of his window and seen the noblewoman riding naked. This legend has inspired many artists in different fields, and nowadays its heroine is very famous and venerated. In particular, this essay focuses on the relation between this legend and compulsive looking (or scopophilia in two renowned films, Rear Window by Alfred Hitchcock, and Peeping Tom by Michael Powell.

  13. Bottlenose dolphin Tursiops truncatus at São Tomé Island (São ...

    African Journals Online (AJOL)

    Although the bottlenose dolphin Tursiops truncatus is one of the most common cetacean species around São Tomé Island, Gulf of Guinea, little research has focused on this species in this region. This study investigated the population of bottlenose dolphins around São Tomé Island by estimating the minimum population ...

  14. Meet TOM - the world's first open chest paediatric/adult manikin.

    Science.gov (United States)

    Dix, Ann

    2016-07-20

    Aged 15, TOM is a model patient. He has suffered more than his fair share of life-threatening events and never complains. But then TOM is not your average sick teenager - he is the world's first open chest paediatric/adult manikin.

  15. 77 FR 51912 - Safety Zone; Tom Lyons Productions Fireworks, Long Island Sound, Sands Point, NY

    Science.gov (United States)

    2012-08-28

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket Number USCG-2012-0618] RIN 1625-AA00 Safety Zone; Tom Lyons Productions Fireworks, Long Island Sound, Sands Point, NY AGENCY.... 165.T01-0618 to read as follows: Sec. 165.T01-0618 Safety Zone; Tom Lyons Productions Fireworks, Long...

  16. 33 CFR 80.170 - Sandy Hook, NJ to Tom's River, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sandy Hook, NJ to Tom's River, NJ. 80.170 Section 80.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.170 Sandy Hook, NJ to Tom's River...

  17. 33 CFR 80.501 - Tom's River, NJ to Cape May, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Tom's River, NJ to Cape May, NJ. 80.501 Section 80.501 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Fifth District § 80.501 Tom's River, NJ to Cape May, NJ...

  18. Challenges and Opportunities: My Personal Journey. Tomás Rivera Lecture Series

    Science.gov (United States)

    Moran, Rachel F.

    2011-01-01

    Each year a distinguished scholar or prominent leader is selected to present the Tomás Rivera Lecture. Named in honor of the late Dr. Tomás Rivera, professor, scholar, poet, and former president of the University of California, Riverside, the American Association of Hispanics in Higher Education (AAHHE) is continuing this lecture at its annual…

  19. Hauntology of Responsibility: Tom Stoppard’s Darkside

    Directory of Open Access Journals (Sweden)

    Tymon Adamczewski

    2017-10-01

    Full Text Available The article centres on the notion of responsibility in Tom Stoppard’s Darkside (2013. While Pink Floyd’s original album, which inspired the playwright, thematises its connection to ethics in a spectral and hauntological manner, through the use of field recording sound snippets interwoven in the music, the radio play explores the notion of responsibility through what is called “thought experiments.” The article identifies the subversive function of these narrative examples and, following Emanuel Levinas’ suggestions concerning the instability of the link between the philosophical discourse and that of examples, shows the latter’s insolent and disruptive nature. The notion of responsibility is further linked to its discussion by Jacques Derrida in his Gift of Death (1995 which consequently makes it possible to view the relation between responsibility and responding from a subversive, hauntological and undecidable perspective.

  20. The legacy of Tom Andersen: The ethics of reflecting processes.

    Science.gov (United States)

    Gehart, Diane R

    2018-03-08

    Tom Andersen and his pioneering work with reflecting conservations has had a lasting influence on the field of family therapy and mental health more broadly. Most family therapists are familiar with his contributions related to reflecting teams; however, fewer are familiar with his conceptualization of reflecting processes, which offer practical ways to approach therapeutic conversations to address challenging problems. This article provides a brief history of Andersen's career and reviews four key elements of his approach, including: (a) his way of being in relationship, (b) appropriately unusual comments, (c) inner and outer dialogs, and (d) ethics of dialogical relating. Finally, this article introduces readers to the context of the video that will be analyzed in the articles that follow in this special section. © 2018 American Association for Marriage and Family Therapy.

  1. The TOM Complex of Amoebozoans: the Cases of the Amoeba Acanthamoeba castellanii and the Slime Mold Dictyostelium discoideum.

    Science.gov (United States)

    Wojtkowska, Małgorzata; Buczek, Dorota; Stobienia, Olgierd; Karachitos, Andonis; Antoniewicz, Monika; Slocinska, Małgorzata; Makałowski, Wojciech; Kmita, Hanna

    2015-07-01

    Protein import into mitochondria requires a wide variety of proteins, forming complexes in both mitochondrial membranes. The TOM complex (translocase of the outer membrane) is responsible for decoding of targeting signals, translocation of imported proteins across or into the outer membrane, and their subsequent sorting. Thus the TOM complex is regarded as the main gate into mitochondria for imported proteins. Available data indicate that mitochondria of representative organisms from across the major phylogenetic lineages of eukaryotes differ in subunit organization of the TOM complex. The subunit organization of the TOM complex in the Amoebozoa is still elusive, so we decided to investigate its organization in the soil amoeba Acanthamoeba castellanii and the slime mold Dictyostelium discoideum. They represent two major subclades of the Amoebozoa: the Lobosa and Conosa, respectively. Our results confirm the presence of Tom70, Tom40 and Tom7 in the A. castellanii and D. discoideum TOM complex, while the presence of Tom22 and Tom20 is less supported. Interestingly, the Tom proteins display the highest similarity to Opisthokonta cognate proteins, with the exception of Tom40. Thus representatives of two major subclades of the Amoebozoa appear to be similar in organization of the TOM complex, despite differences in their lifestyle. Copyright © 2015 The Authors. Published by Elsevier GmbH.. All rights reserved.

  2. Plasticity of TOM complex assembly in skeletal muscle mitochondria in response to chronic contractile activity.

    Science.gov (United States)

    Joseph, Anna-Maria; Hood, David A

    2012-03-01

    We investigated the assembly of the TOM complex within skeletal muscle under conditions of chronic contractile activity-induced mitochondrial biogenesis. Tom40 import into mitochondria was increased by chronic contractile activity, as was its time-dependent assembly into the TOM complex. These changes coincided with contractile activity-induced augmentations in the expression of key protein import machinery components Tim17, Tim23, and Tom22, as well as the cytosolic chaperone Hsp90. These data indicate the adaptability of the TOM protein import complex and suggest a regulatory role for the assembly of this complex in exercise-induced mitochondrial biogenesis. Copyright © 2011 Elsevier B.V. and Mitochondria Research Society. All rights reserved. All rights reserved.

  3. Measuring theory of mind in children. Psychometric properties of the ToM Storybooks.

    Science.gov (United States)

    Blijd-Hoogewys, E M A; van Geert, P L C; Serra, M; Minderaa, R B

    2008-11-01

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various emotions, beliefs, desires and mental-physical distinctions. Four studies on the validity and reliability of the test are presented, in typically developing children (n = 324, 3-12 years) and children with PDD-NOS (n = 30). The ToM Storybooks have good psychometric qualities. A component analysis reveals five components corresponding with the underlying theoretical constructs. The internal consistency, test-retest reliability, inter-rater reliability, construct validity and convergent validity are good. The ToM Storybooks can be used in research as well as in clinical settings.

  4. TOMS EP UV Aerosol Index Daily and Monthly Zonal Means V008 (TOMSEPL3zaer) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/EP UV Aerosol Index Daily and Monthly Zonal Means Version 8 data in ASCII format.The Total Ozone Mapping Spectrometer (TOMS) Version...

  5. 77 FR 57477 - Delegation of Certain Functions and Authority Under Section 5(a) of the Tom Lantos Block Burmese...

    Science.gov (United States)

    2012-09-17

    ...--Delegation of Certain Functions and Authority Under Section 5(a) of the Tom Lantos Block Burmese Junta's Anti... 5(a) of the Tom Lantos Block Burmese Junta's Anti-Democratic Efforts Act of 2008 Memorandum for the... section 5(a)(2) of the Tom Lantos Block Burmese Junta's Anti- Democratic Efforts Act of 2008 (Public Law...

  6. Hombres. Don Tomás Rueda Vargas

    Directory of Open Access Journals (Sweden)

    Boletin Cultural y Bibliográfico Banco de la República

    1958-07-01

    Full Text Available Quince años hizo el 25 de julio que desapareció de entre nosotros don Tomás Rueda Vargas. Su nombre, ejemplar por muchos conceptos, viene siempre nimbado de las virtudes cardinales que conformaron su tarea y su vida. Escritor nato,  sabía manejar el idioma con singular pericia sin caer en  rebuscamientos  ni  en  gongorismos. Su  pensamiento era diáfano por  lo cual no se  perdía en  el laberinto de  las palabras.   Apenas éstas eran  el dócil  instrumento para su dialéctica, para ese  generoso razo­  namiento intelectual que constituía el  Alfa  y el Omega   de  su diario batallar.

  7. São Tomé and Príncipe - Business Environment and Tax Reform

    Data.gov (United States)

    Millennium Challenge Corporation — This report is a summative evaluation of the Millennium Challenge Corporation's (MCC) Threshold Country Program (TCP) for São Tomé and Príncipe. The program was...

  8. Lateral release of proteins from the TOM complex into the outer membrane of mitochondria.

    Science.gov (United States)

    Harner, Max; Neupert, Walter; Deponte, Marcel

    2011-07-15

    The TOM complex of the outer membrane of mitochondria is the entry gate for the vast majority of precursor proteins that are imported into the mitochondria. It is made up by receptors and a protein conducting channel. Although precursor proteins of all subcompartments of mitochondria use the TOM complex, it is not known whether its channel can only mediate passage across the outer membrane or also lateral release into the outer membrane. To study this, we have generated fusion proteins of GFP and Tim23 which are inserted into the inner membrane and, at the same time, are spanning either the TOM complex or are integrated into the outer membrane. Our results demonstrate that the TOM complex, depending on sequence determinants in the precursors, can act both as a protein conducting pore and as an insertase mediating lateral release into the outer membrane.

  9. AuTom: a novel automatic platform for electron tomography reconstruction

    KAUST Repository

    Han, Renmin

    2017-07-26

    We have developed a software package towards automatic electron tomography (ET): Automatic Tomography (AuTom). The presented package has the following characteristics: accurate alignment modules for marker-free datasets containing substantial biological structures; fully automatic alignment modules for datasets with fiducial markers; wide coverage of reconstruction methods including a new iterative method based on the compressed-sensing theory that suppresses the “missing wedge” effect; and multi-platform acceleration solutions that support faster iterative algebraic reconstruction. AuTom aims to achieve fully automatic alignment and reconstruction for electron tomography and has already been successful for a variety of datasets. AuTom also offers user-friendly interface and auxiliary designs for file management and workflow management, in which fiducial marker-based datasets and marker-free datasets are addressed with totally different subprocesses. With all of these features, AuTom can serve as a convenient and effective tool for processing in electron tomography.

  10. SAFARI 2000 TOMS Aerosol Index Data, Southern Africa, Dry Season 2000

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: Daily Aerosol Index (AI) data from Earth Probe (EP) Total Ozone Mapping Spectrometer (TOMS) for the period of August 12-September 25, 2000 were processed...

  11. SAFARI 2000 TOMS Tropospheric Ozone Data, Southern Africa Subset, Dry Season 2000

    Data.gov (United States)

    National Aeronautics and Space Administration — Tropical Tropospheric Ozone (TTO) data from Earth Probe (EP) Total Ozone Mapping Spectrometer (TOMS) for the period of August 8-September 29, 2000 were processed and...

  12. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    OpenAIRE

    Løfaldli, Eli

    2017-01-01

    As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749). In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly...

  13. Short Note New hope for the critically endangered São Tomé ...

    African Journals Online (AJOL)

    However, this new site lies outside the Ôbo Natural Park, São Tomé's only protected area, for which we alert the need to better protect its surroundings, which are relevant for many of the island's endemic species. Keywords: buffer zone, conservation, distribution, Ôbo Natural Park, playback, São Tomé and Príncipe

  14. Nimble Negotiators: How Theory of Mind (ToM) Interconnects with Persuasion Skills in Children with and without ToM Delay

    Science.gov (United States)

    Peterson, Candida C.; Slaughter, Virginia; Wellman, Henry M.

    2018-01-01

    Persuasion is an essential social skill. Yet its development and underpinnings are poorly understood. In 2 studies, a total of 167 children aged 3 to 12 years took theory of mind (ToM) tests and participated in unscripted, seminaturalistic persuasive conversations. Children were typically developing (TD) or had deafness or autism spectrum disorder…

  15. An Expanded UV Irradiance Database from TOMS Including the Effects of Ozone, Clouds, and Aerosol Attenuation

    Science.gov (United States)

    Herman, J.; Krotkov, N.

    2003-01-01

    The TOMS UV irradiance database (1978 to 2003) has been expanded to include five new products (noon irradiance at 305,310,324, and 380 nm, and noon erythemal-weighted irradiance), in addition to the existing erythemal daily exposure, that permit direct comparisons with ground-based measurements from spectrometers and broadband instruments. The new data are available on http://toms.gsfc.nasa.gov/>http://toms.gsfc.nasa.gov. Comparisons of the TOMS estimated irradiances with ground-based instruments are given along with a review of the sources of known errors, especially the recent improvements in accounting for aerosol attenuation. Trend estimations from the new TOMS irradiances permit the clear separation of changes caused by ozone and those caused by aerosols and clouds. Systematic differences in cloud cover are shown to be the most important factor in determining regional differences in UV radiation reaching the ground for locations at the same latitude (e.g., the summertime differences between Australia and the US southwest).

  16. Cooperation of TOM and TIM23 complexes during translocation of proteins into mitochondria.

    Science.gov (United States)

    Waegemann, Karin; Popov-Čeleketić, Dušan; Neupert, Walter; Azem, Abdussalam; Mokranjac, Dejana

    2015-03-13

    Translocation of the majority of mitochondrial proteins from the cytosol into mitochondria requires the cooperation of TOM and TIM23 complexes in the outer and inner mitochondrial membranes. The molecular mechanisms underlying this cooperation remain largely unknown. Here, we present biochemical and genetic evidence that at least two contacts from the side of the TIM23 complex play an important role in TOM-TIM23 cooperation in vivo. Tim50, likely through its very C-terminal segment, interacts with Tom22. This interaction is stimulated by translocating proteins and is independent of any other TOM-TIM23 contact known so far. Furthermore, the exposure of Tim23 on the mitochondrial surface depends not only on its interaction with Tim50 but also on the dynamics of the TOM complex. Destabilization of the individual contacts reduces the efficiency of import of proteins into mitochondria and destabilization of both contacts simultaneously is not tolerated by yeast cells. We conclude that an intricate and coordinated network of protein-protein interactions involving primarily Tim50 and also Tim23 is required for efficient translocation of proteins across both mitochondrial membranes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Extension of Tom Booth's Modified Power Method for Higher Eigen Modes

    International Nuclear Information System (INIS)

    Zhang, Peng; Lee, Hyunsuk; Lee, Deokjung

    2015-01-01

    A possible technique to get the even higher modes is suggested, but it is difficult to be applied practically. In this paper, a general solution strategy is proposed, which can extend Tom Booth's modified power method to get the higher Eigenmodes and there is no limitation about the number of Eigenmodes that can be obtained with this method. In this paper, a general solution strategy is proposed, which can extend Tom Booth's modified power method to get the higher Eigenmodes and there is no limitation about the number of Eigenmodes that can be obtained with this method. It is more practical than the original solution strategy that Tom Booth proposed. The implementation of the method in Monte Carlo code shows significant advantages comparing to the original power method

  18. Micro-Tom Tomato as an Alternative Plant Model System: Mutant Collection and Efficient Transformation.

    Science.gov (United States)

    Shikata, Masahito; Ezura, Hiroshi

    2016-01-01

    Tomato is a model plant for fruit development, a unique feature that classical model plants such as Arabidopsis and rice do not have. The tomato genome was sequenced in 2012 and tomato is becoming very popular as an alternative system for plant research. Among many varieties of tomato, Micro-Tom has been recognized as a model cultivar for tomato research because it shares some key advantages with Arabidopsis including its small size, short life cycle, and capacity to grow under fluorescent lights at a high density. Mutants and transgenic plants are essential materials for functional genomics research, and therefore, the availability of mutant resources and methods for genetic transformation are key tools to facilitate tomato research. Here, we introduce the Micro-Tom mutant database "TOMATOMA" and an efficient transformation protocol for Micro-Tom.

  19. Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1.

    Science.gov (United States)

    Gracheva, Elena O; Maryon, Ed B; Berthelot-Grosjean, Martine; Richmond, Janet E

    2010-01-01

    The assembly of SNARE complexes between syntaxin, SNAP-25 and synaptobrevin is required to prime synaptic vesicles for fusion. Since Munc18 and tomosyn compete for syntaxin interactions, the interplay between these proteins is predicted to be important in regulating synaptic transmission. We explored this possibility, by examining genetic interactions between C. elegans unc-18(Munc18), unc-64(syntaxin) and tom-1(tomosyn). We have previously demonstrated that unc-18 mutants have reduced synaptic transmission, whereas tom-1 mutants exhibit enhanced release. Here we show that the unc-18 mutant release defect is associated with loss of two morphologically distinct vesicle pools; those tethered within 25 nm of the plasma membrane and those docked with the plasma membrane. In contrast, priming defective unc-13 mutants accumulate tethered vesicles, while docked vesicles are greatly reduced, indicating tethering is UNC-18-dependent and occurs in the absence of priming. C. elegans unc-64 mutants phenocopy unc-18 mutants, losing both tethered and docked vesicles, whereas overexpression of open syntaxin preferentially increases vesicle docking, suggesting UNC-18/closed syntaxin interactions are responsible for vesicle tethering. Given the competition between vertebrate tomosyn and Munc18, for syntaxin binding, we hypothesized that C. elegans TOM-1 may inhibit both UNC-18-dependent vesicle targeting steps. Consistent with this hypothesis, tom-1 mutants exhibit enhanced UNC-18 plasma membrane localization and a concomitant increase in both tethered and docked synaptic vesicles. Furthermore, in tom-1;unc-18 double mutants the docked, primed vesicle pool is preferentially rescued relative to unc-18 single mutants. Together these data provide evidence for the differential regulation of two vesicle targeting steps by UNC-18 and TOM-1 through competitive interactions with syntaxin.

  20. Differential regulation of synaptic vesicle tethering and docking by UNC-18 and TOM-1

    Directory of Open Access Journals (Sweden)

    Elena O Gracheva

    2010-10-01

    Full Text Available The assembly of SNARE complexes between syntaxin, SNAP-25 and synaptobrevin is required to prime synaptic vesicles for fusion. Since Munc18 and tomosyn compete for syntaxin interactions, the interplay between these proteins is predicted to be important in regulating synaptic transmission. We explored this possibility, by examining genetic interactions between C. elegans unc-18(Munc18, unc-64(syntaxin and tom-1(tomosyn. We have previously demonstrated that unc-18 mutants have reduced synaptic transmission, whereas tom-1 mutants exhibit enhanced release. Here we show that the unc-18 mutant release defect is associated with loss of two morphologically distinct vesicle pools; those tethered within 25nm of the plasma membrane and those docked with the plasma membrane. In contrast, priming defective unc-13 mutants accumulate tethered vesicles, while docked vesicles are greatly reduced, indicating tethering is UNC-18-dependent and occurs in the absence of priming. C. elegans unc-64 mutants phenocopy unc-18 mutants, losing both tethered and docked vesicles, whereas overexpression of open syntaxin preferentially increases vesicle docking, suggesting UNC-18/closed syntaxin interactions are responsible for vesicle tethering. Given the competition between vertebrate tomosyn and Munc18, for syntaxin binding, we hypothesized that C. elegans TOM-1 may inhibit both UNC-18-dependent vesicle targeting steps. Consistent with this hypothesis, tom-1 mutants exhibit enhanced UNC-18 plasma membrane localization and a concomitant increase in both tethered and docked synaptic vesicles. Furthermore, in tom-1;unc-18 double mutants the docked, primed vesicle pool is preferentially rescued relative to unc-18 single mutants. Together these data provide evidence for the differential regulation of two vesicle targeting steps by UNC-18 and TOM-1 through competitive interactions with syntaxin

  1. The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM).

    Science.gov (United States)

    Frank, Daniel O; Dengjel, Jörn; Wilfling, Florian; Kozjak-Pavlovic, Vera; Häcker, Georg; Weber, Arnim

    2015-01-01

    The pro-apoptotic Bcl-2-family protein Bim belongs to the BH3-only proteins known as initiators of apoptosis. Recent data show that Bim is constitutively inserted in the outer mitochondrial membrane via a C-terminal transmembrane anchor from where it can activate the effector of cytochrome c-release, Bax. To identify regulators of Bim-activity, we conducted a search for proteins interacting with Bim at mitochondria. We found an interaction of Bim with Tom70, Tom20 and more weakly with Tom40, all components of the Translocase of the Outer Membrane (TOM). In vitro import assays performed on tryptically digested yeast mitochondria showed reduced Bim insertion into the outer mitochondrial membrane (OMM) indicating that protein receptors may be involved in the import process. However, RNAi against components of TOM (Tom40, Tom70, Tom22 or Tom20) by siRNA, individually or in combination, did not consistently change the amount of Bim on HeLa mitochondria, either at steady state or upon de novo-induction. In support of this, the individual or combined knock-downs of TOM receptors also failed to alter the susceptibility of HeLa cells to Bim-induced apoptosis. In isolated yeast mitochondria, lack of Tom70 or the TOM-components Tom20 or Tom22 alone did not affect the import of Bim into the outer mitochondrial membrane. In yeast, expression of Bim can sensitize the cells to Bax-dependent killing. This sensitization was unaffected by the absence of Tom70 or by an experimental reduction in Tom40. Although thus the physiological role of the Bim-TOM-interaction remains unclear, TOM complex components do not seem to be essential for Bim insertion into the OMM. Nevertheless, this association should be noted and considered when the regulation of Bim in other cells and situations is investigated.

  2. The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM.

    Directory of Open Access Journals (Sweden)

    Daniel O Frank

    Full Text Available The pro-apoptotic Bcl-2-family protein Bim belongs to the BH3-only proteins known as initiators of apoptosis. Recent data show that Bim is constitutively inserted in the outer mitochondrial membrane via a C-terminal transmembrane anchor from where it can activate the effector of cytochrome c-release, Bax. To identify regulators of Bim-activity, we conducted a search for proteins interacting with Bim at mitochondria. We found an interaction of Bim with Tom70, Tom20 and more weakly with Tom40, all components of the Translocase of the Outer Membrane (TOM. In vitro import assays performed on tryptically digested yeast mitochondria showed reduced Bim insertion into the outer mitochondrial membrane (OMM indicating that protein receptors may be involved in the import process. However, RNAi against components of TOM (Tom40, Tom70, Tom22 or Tom20 by siRNA, individually or in combination, did not consistently change the amount of Bim on HeLa mitochondria, either at steady state or upon de novo-induction. In support of this, the individual or combined knock-downs of TOM receptors also failed to alter the susceptibility of HeLa cells to Bim-induced apoptosis. In isolated yeast mitochondria, lack of Tom70 or the TOM-components Tom20 or Tom22 alone did not affect the import of Bim into the outer mitochondrial membrane. In yeast, expression of Bim can sensitize the cells to Bax-dependent killing. This sensitization was unaffected by the absence of Tom70 or by an experimental reduction in Tom40. Although thus the physiological role of the Bim-TOM-interaction remains unclear, TOM complex components do not seem to be essential for Bim insertion into the OMM. Nevertheless, this association should be noted and considered when the regulation of Bim in other cells and situations is investigated.

  3. Technical evaluation of Tom Scurry Associates: Model PM-203 doorway monitor

    International Nuclear Information System (INIS)

    1978-07-01

    Under a basic assignment by the Office of Safeguards and Security, the Tom Scurry Associates Model PM-203 Personnel Doorway SNM Monitor manufactured by Tom Scurry Associates was evaluated by LASL Group Q-2 against the DOE Personnel Doorway Monitor standards. During the evaluation, a small change was required in detector shielding to eliminate low sensitivity areas at the portal sides. With the modified shielding described, the PM-203 meets the Office of Safeguards and Security SNM doorway monitor specifications for detecting either 235 U or 239 Pu-- 233 U. This system is also capable of monitoring 238 Pu

  4. Genome-wide analysis of intraspecific DNA polymorphism in 'Micro-Tom', a model cultivar of tomato (Solanum lycopersicum).

    Science.gov (United States)

    Kobayashi, Masaaki; Nagasaki, Hideki; Garcia, Virginie; Just, Daniel; Bres, Cécile; Mauxion, Jean-Philippe; Le Paslier, Marie-Christine; Brunel, Dominique; Suda, Kunihiro; Minakuchi, Yohei; Toyoda, Atsushi; Fujiyama, Asao; Toyoshima, Hiromi; Suzuki, Takayuki; Igarashi, Kaori; Rothan, Christophe; Kaminuma, Eli; Nakamura, Yasukazu; Yano, Kentaro; Aoki, Koh

    2014-02-01

    Tomato (Solanum lycopersicum) is regarded as a model plant of the Solanaceae family. The genome sequencing of the tomato cultivar 'Heinz 1706' was recently completed. To accelerate the progress of tomato genomics studies, systematic bioresources, such as mutagenized lines and full-length cDNA libraries, have been established for the cultivar 'Micro-Tom'. However, these resources cannot be utilized to their full potential without the completion of the genome sequencing of 'Micro-Tom'. We undertook the genome sequencing of 'Micro-Tom' and here report the identification of single nucleotide polymorphisms (SNPs) and insertion/deletions (indels) between 'Micro-Tom' and 'Heinz 1706'. The analysis demonstrated the presence of 1.23 million SNPs and 0.19 million indels between the two cultivars. The density of SNPs and indels was high in chromosomes 2, 5 and 11, but was low in chromosomes 6, 8 and 10. Three known mutations of 'Micro-Tom' were localized on chromosomal regions where the density of SNPs and indels was low, which was consistent with the fact that these mutations were relatively new and introgressed into 'Micro-Tom' during the breeding of this cultivar. We also report SNP analysis for two 'Micro-Tom' varieties that have been maintained independently in Japan and France, both of which have served as standard lines for 'Micro-Tom' mutant collections. Approximately 28,000 SNPs were identified between these two 'Micro-Tom' lines. These results provide high-resolution DNA polymorphic information on 'Micro-Tom' and represent a valuable contribution to the 'Micro-Tom'-based genomics resources.

  5. Tom Rüütel: Tööandjal on igal juhul kasud sees / intervjueerinud Helen Kask

    Index Scriptorium Estoniae

    Rüütel, Tom

    2013-01-01

    Kui oluliseks peab Tom töötamist ning millisena näeb ta tööandjate suhtumst erivajadusega töötajasse? Millised on Tomi mõtted seoses töövõimetoetuse (TVK) reformiga? Tom Rüütel õpib Tallinna Ülikoolis magistrantuuri teisel kursusel rakenduslikku sotsiaaltööd

  6. Training Preschoolers on First-Order False Belief Understanding: Transfer on Advanced ToM Skills and Metamemory

    Science.gov (United States)

    Lecce, Serena; Bianco, Federica; Demicheli, Patrizia; Cavallini, Elena

    2014-01-01

    This study investigated the relation between theory of mind (ToM) and metamemory knowledge using a training methodology. Sixty-two 4- to 5-year-old children were recruited and randomly assigned to one of two training conditions: A first-order false belief (ToM) and a control condition. Intervention and control groups were equivalent at pretest for…

  7. Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting β-barrel biogenesis.

    Science.gov (United States)

    Wenz, Lena-Sophie; Ellenrieder, Lars; Qiu, Jian; Bohnert, Maria; Zufall, Nicole; van der Laan, Martin; Pfanner, Nikolaus; Wiedemann, Nils; Becker, Thomas

    2015-09-28

    Biogenesis of mitochondrial β-barrel proteins requires two preprotein translocases, the general translocase of the outer membrane (TOM) and the sorting and assembly machinery (SAM). TOM and SAM form a supercomplex that promotes transfer of β-barrel precursors. The SAM core complex contains the channel protein Sam50, which cooperates with Sam35 in precursor recognition, and the peripheral membrane protein Sam37. The molecular function of Sam37 has been unknown. We report that Sam37 is crucial for formation of the TOM-SAM supercomplex. Sam37 interacts with the receptor domain of Tom22 on the cytosolic side of the mitochondrial outer membrane and links TOM and SAM complexes. Sam37 thus promotes efficient transfer of β-barrel precursors to the SAM complex. We conclude that Sam37 functions as a coupling factor of the translocase supercomplex of the mitochondrial outer membrane. © 2015 Wenz et al.

  8. Collateral Damage: Veterans and Domestic Violence in Mari Sandoz's "The Tom-Walker"

    Science.gov (United States)

    Bahr, Kathy

    2010-01-01

    "The Tom-Walker" combines the best of Sandoz's realism with her worst attempts at moralizing. Unable to divine exactly what political configuration right-wing post-World War II sentiments might take, Sandoz nevertheless feared a fascist uprising in this country. Perhaps because these concerns dominated her thoughts at the time, she allowed her…

  9. Toward a Latino Attainment Agenda: Shaping Our Own Destiny. Tomás Rivera Lecture Series

    Science.gov (United States)

    Cigarroa, Francisco G.

    2013-01-01

    In the 2013 Tomás Rivera lecture, Francisco Cigarroa, chancellor of the University of Texas system, discusses how a major shift in the demographics of the United States is having a profound effect on K-12 and higher education.

  10. ROMS/TOMS Tangent Linear and Adjoint Models: Testing and Applications

    National Research Council Canada - National Science Library

    Miller, Arthur J; Cornuelle, Bruce D

    2004-01-01

    ... (Regional Ocean Modeling System/Terrain-Following Ocean Modeling System) that is suitable for general use by the ROMS/TOMS community and to develop computational platforms based on the TLM and ADM for 4D variational data assimilation (4DVar...

  11. Systematic Comparison of Brain Imaging Meta-Analyses of ToM with vPT.

    Science.gov (United States)

    Arora, Aditi; Schurz, Matthias; Perner, Josef

    2017-01-01

    In visual perspective taking (vPT) one has to concern oneself with what other people see and how they see it. Since seeing is a mental state, developmental studies have discussed vPT within the domain of "theory of mind (ToM)" but imaging studies have not treated it as such. Based on earlier results from several meta-analyses, we tested for the overlap of visual perspective taking studies with 6 different kinds of ToM studies: false belief, trait judgments, strategic games, social animations, mind in the eyes, and rational actions. Joint activation was observed between the vPT task and some kinds of ToM tasks in regions involving the left temporoparietal junction (TPJ), anterior precuneus, left middle occipital gyrus/extrastriate body area (EBA), and the left inferior frontal and precentral gyrus. Importantly, no overlap activation was found for the vPT tasks with the joint core of all six kinds of ToM tasks. This raises the important question of what the common denominator of all tasks that fall under the label of "theory of mind" is supposed to be if visual perspective taking is not one of them.

  12. SIM PlanetQuest: The TOM-3 (Thermo-Optical-Mechanical) Siderostat Mirror Test

    Science.gov (United States)

    Phillips, Charles J.

    2006-01-01

    This slide presentation reviews the Space Interferometry Mission (SIM) PlanetQuest mission. It describes the mission, shows diagrams of the instrument, the collector bays, the Siderostat mirrors, the COL bay thermal environment, the TOM-3 replicating COL Bay Environment, the thermal hardware for the SID heater control, and the results of the test are shown

  13. Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting.

    Science.gov (United States)

    Chacinska, Agnieszka; van der Laan, Martin; Mehnert, Carola S; Guiard, Bernard; Mick, David U; Hutu, Dana P; Truscott, Kaye N; Wiedemann, Nils; Meisinger, Chris; Pfanner, Nikolaus; Rehling, Peter

    2010-01-01

    Mitochondrial import of cleavable preproteins occurs at translocation contact sites, where the translocase of the outer membrane (TOM) associates with the presequence translocase of the inner membrane (TIM23) in a supercomplex. Different views exist on the mechanism of how TIM23 mediates preprotein sorting to either the matrix or inner membrane. On the one hand, two TIM23 forms were proposed, a matrix transport form containing the presequence translocase-associated motor (PAM; TIM23-PAM) and a sorting form containing Tim21 (TIM23(SORT)). On the other hand, it was reported that TIM23 and PAM are permanently associated in a single-entity translocase. We have accumulated distinct transport intermediates of preproteins to analyze the translocases in their active, preprotein-carrying state. We identified two different forms of active TOM-TIM23 supercomplexes, TOM-TIM23(SORT) and TOM-TIM23-PAM. These two supercomplexes do not represent separate pathways but are in dynamic exchange during preprotein translocation and sorting. Depending on the signals of the preproteins, switches between the different forms of supercomplex and TIM23 are required for the completion of preprotein import.

  14. AuTom: a novel automatic platform for electron tomography reconstruction

    KAUST Repository

    Han, Renmin; Wan, Xiaohua; Wang, Zihao; Hao, Yu; Zhang, Jingrong; Chen, Yu; Gao, Xin; Liu, Zhiyong; Ren, Fei; Sun, Fei; Zhang, Fa

    2017-01-01

    -friendly interface and auxiliary designs for file management and workflow management, in which fiducial marker-based datasets and marker-free datasets are addressed with totally different subprocesses. With all of these features, AuTom can serve as a convenient

  15. evaluation of the nutritional quality of “tom brown” weaning diet

    African Journals Online (AJOL)

    Admin

    nutritional quality of “Tom Brown” was evaluated from its total nitrogen and protein ... were significantly higher (P<0.05) than those for rats on reference diet; while protein .... Drug House (BDH) Chemical Ltd, Pole, England, and .... reproduction, protection and regulation of various body .... Official Methods of Analysis. 15th.

  16. Tom Brown to direct Office for Student Life at Virginia Tech

    OpenAIRE

    Cox, Clara B.

    2004-01-01

    James Thomas "Tom" Brown of Blacksburg, Va., former interim director of the Office for Student Life and Advocacy, has been named director of the office, which has been renamed the Office for Student Life. The newly named office is responsible for multicultural programs, student advocacy, orientation, parent programs, and response to student emergencies.

  17. The Decade Ahead: Inquire, Innovate, Impact. Tomás Rivera Lecture Series

    Science.gov (United States)

    Pacheco, Manuel T.

    2015-01-01

    In the 2015 Tomás Rivera lecture, Manuel T. Pacheco, President Emeritus of the University of Missouri System and the University of Arizona, discusses the importance of representing the Hispanic American population proportionately among college students, faculty, staff, and administration in higher education.

  18. Tom Beaver, Creek Television Reporter. With Teacher's Guide. Native Americans of the Twentieth Century.

    Science.gov (United States)

    Minneapolis Public Schools, MN.

    A biography for elementary school students presents an account of an American Indian television reporter, Tom Beaver (Creek), and includes a map of Oklahoma showing the location of Indian tribes. A teacher's guide following the biography contains information about the Creek tribe and the history of television, learning objectives and directions…

  19. Camus' Actor as Tom Stoppard's Player; A Key to Interpreting "Rosencrantz and Guildenstern Are Dead."

    Science.gov (United States)

    Zivanovic, Judith

    An examination of Albert Camus' definition of the actor in "The Myth on Sisyphus" helps to illuminate the character and role of The Player in Tom Stoppard's play and, hence, to bring light to an understanding of the philosophy of the play itself. The actor, for Camus, reveals our mortality in the face of the absurdity of our mortality,…

  20. Hydrology and Coastal Morphology at São Tomé

    NARCIS (Netherlands)

    Giardino, A.; Bettencourt, S.; Carvalho, A.; Filatova, Tatiana; de Keizer, O.; Schellekens, J.; Ottow, B.

    2012-01-01

    The Democratic Republic of São Tomé and Principe is an archipelago comprised of two main islands and several islets located in the Gulf of Guinea 350 km off the west coast of Africa. Villages of in the archipelago are built close to the coastline and have historically suffered from high rates of

  1. Errors resulting from assuming opaque Lambertian clouds in TOMS ozone retrieval

    International Nuclear Information System (INIS)

    Liu, X.; Newchurch, M.J.; Loughman, R.; Bhartia, P.K.

    2004-01-01

    Accurate remote sensing retrieval of atmospheric constituents over cloudy areas is very challenging because of insufficient knowledge of cloud parameters. Cloud treatments are highly idealized in most retrieval algorithms. Using a radiative transfer model treating clouds as scattering media, we investigate the effects of assuming opaque Lambertian clouds and employing a Partial Cloud Model (PCM) on Total Ozone Mapping Spectrometer (TOMS) ozone retrievals, especially for tropical high-reflectivity clouds. Assuming angularly independent cloud reflection is good because the Ozone Retrieval Errors (OREs) are within 1.5% of the total ozone (i.e., within TOMS retrieval precision) when Cloud Optical Depth (COD)≥20. Because of Intra-Cloud Ozone Absorption ENhancement (ICOAEN), assuming opaque clouds can introduce large OREs even for optically thick clouds. For a water cloud of COD 40 spanning 2-12 km with 20.8 Dobson Unit (DU) ozone homogeneously distributed in the cloud, the ORE is 17.8 DU in the nadir view. The ICOAEN effect depends greatly on solar zenith angle, view zenith angle, and intra-cloud ozone amount and distribution. The TOMS PCM is good because negative errors from the cloud fraction being underestimated partly cancel other positive errors. At COD≤5, the TOMS algorithm retrieves approximately the correct total ozone because of compensating errors. With increasing COD up to 20-40, the overall positive ORE increases and is finally dominated by the ICOAEN effect. The ICOAEN effect is typically 5-13 DU on average over the Atlantic and Africa and 1-7 DU over the Pacific for tropical high-altitude (cloud top pressure ≤300 hPa) and high-reflectivity (reflectivity ≥ 80%) clouds. Knowledge of TOMS ozone retrieval errors has important implications for remote sensing of ozone/trace gases from other satellite instruments

  2. Transcultural differences in brain activation patterns during theory of mind (ToM) task performance in Japanese and Caucasian participants.

    Science.gov (United States)

    Koelkebeck, Katja; Hirao, Kazuyuki; Kawada, Ryousaku; Miyata, Jun; Saze, Teruyasu; Ubukata, Shiho; Itakura, Shoji; Kanakogi, Yasuhiro; Ohrmann, Patricia; Bauer, Jochen; Pedersen, Anya; Sawamoto, Nobukatsu; Fukuyama, Hidenao; Takahashi, Hidehiko; Murai, Toshiya

    2011-01-01

    Theory of mind (ToM) functioning develops during certain phases of childhood. Factors such as language development and educational style seem to influence its development. Some studies that have focused on transcultural aspects of ToM development have found differences between Asian and Western cultures. To date, however, little is known about transcultural differences in neural activation patterns as they relate to ToM functioning. The aim of our study was to observe ToM functioning and differences in brain activation patterns, as assessed by functional magnetic resonance imaging (fMRI). This study included a sample of 18 healthy Japanese and 15 healthy Caucasian subjects living in Japan. We presented a ToM task depicting geometrical shapes moving in social patterns. We also administered questionnaires to examine empathy abilities and cultural background factors. Behavioral data showed no significant group differences in the subjects' post-scan descriptions of the movies. The imaging results displayed stronger activation in the medial prefrontal cortex (MPFC) in the Caucasian sample during the presentation of ToM videos. Furthermore, the task-associated activation of the MPFC was positively correlated with autistic and alexithymic features in the Japanese sample. In summary, our results showed evidence of culturally dependent sociobehavioral trait patterns, which suggests that they have an impact on brain activation patterns during information processing involving ToM.

  3. Tropospheric Ozone Pollution from Space: New Views from the TOMS (Total Ozone Mapping Spectrometer) Instrument

    Science.gov (United States)

    Thompson, Anne M.; Hudson, Robert D.; Frolov, Alexander D.; Witte, Jacquelyn C.; Kucsera, Tom L.; Einaudi, Franco (Technical Monitor)

    2000-01-01

    New products from the TOMS (Total Ozone Mapping Spectrometer) >satellite instrument can resolve pollution events in tropical and mid-latitudes, Over the past several years, we have developed tropospheric ozone data sets by two methods. The modified-residual technique [Hudson and Thompson, 1998; Thompson and Hudson, 1999] uses v. 7 TOMS total ozone and is applicable to tropical regimes in which the wave-one pattern in total ozone is observed. The TOMSdirect method [Hudson et at., 2000] represents a new algorithm that uses TOMS radiances to extract tropospheric ozone in regions of constant stratospheric ozone and tropospheric ozone displaying high mixing ratios and variability characteristic of pollution, Absorbing aerosols (dust and smoke; Herman et at., 1997 Hsu et al., 1999), a standard TOMS product, provide transport and/or source marker information to interpret tropospheric ozone. For the Nimbus 7/TOMS observing period (1979-1992), modified-residual TTO (tropical tropospheric ozone) appears as two maps/month at I-degree latitude 2-degree longitude resolution at a homepage and digital data are available (20S to 20N) by ftp at http://metosrv2. umd.edu/tropo/ 14y_data.d. Preliminary modified-residual TTO data from the operational Earth-Probe/TOMS (1996- present) are posted in near-real-time at the same website. Analyses with the new tropospheric ozone and aerosol data are illustrated by the following (I)Signals in tropical tropospheric ozone column and smoke amount during ENSO (El Nino-Southern Oscillation) events, e.g. 1982-1983 and the intense ENSO induced biomass fires of 1997-1998 over the Indonesian region [Thompson et a[, 2000a, Thompson and Hudson, 1999]. (2) Trends in tropospheric ozone and smoke aerosols in various tropical regions (Atlantic, Pacific, Africa, Brazil). No significant trends were found for ozone from1980-1990 [Thompson and Hudson, 19991 although smoke aerosols increased during the period [Hsu et al.,1999]. (3) Temporal and spatial offsets

  4. Interpretation of TOMS Observations of Tropical Tropospheric Ozone with a Global Model and In Situ Observations

    Science.gov (United States)

    Martin, Randall V.; Jacob, Daniel J.; Logan, Jennifer A.; Bey, Isabelle; Yantosca, Robert M.; Staudt, Amanda C.; Fiore, Arlene M.; Duncan, Bryan N.; Liu, Hongyu; Ginoux, Paul

    2004-01-01

    We interpret the distribution of tropical tropospheric ozone columns (TTOCs) from the Total Ozone Mapping Spectrometer (TOMS) by using a global three-dimensional model of tropospheric chemistry (GEOS-CHEM) and additional information from in situ observations. The GEOS-CHEM TTOCs capture 44% of the variance of monthly mean TOMS TTOCs from the convective cloud differential method (CCD) with no global bias. Major discrepancies are found over northern Africa and south Asia where the TOMS TTOCs do not capture the seasonal enhancements from biomass burning found in the model and in aircraft observations. A characteristic feature of these northern topical enhancements, in contrast to southern tropical enhancements, is that they are driven by the lower troposphere where the sensitivity of TOMS is poor due to Rayleigh scattering. We develop an efficiency correction to the TOMS retrieval algorithm that accounts for the variability of ozone in the lower troposphere. This efficiency correction increases TTOC's over biomass burning regions by 3-5 Dobson units (DU) and decreases them by 2-5 DU over oceanic regions, improving the agreement between CCD TTOCs and in situ observations. Applying the correction to CCD TTOCs reduces by approximately DU the magnitude of the "tropical Atlantic paradox" [Thompson et al, 2000], i.e. the presence of a TTOC enhancement over the southern tropical Atlantic during the northern African biomass burning season in December-February. We reproduce the remainder of the paradox in the model and explain it by the combination of upper tropospheric ozone production from lightning NOx, peristent subsidence over the southern tropical Atlantic as part of the Walker circulation, and cross-equatorial transport of upper tropospheric ozone from northern midlatitudes in the African "westerly duct." These processes in the model can also account for the observed 13-17 DU persistent wave-1 pattern in TTOCs with a maximum above the tropical Atlantic and a minimum

  5. miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression.

    LENUS (Irish Health Repository)

    Oglesby, Irene K

    2010-02-15

    Cystic fibrosis (CF) is one of the most common lethal genetic diseases in which the role of microRNAs has yet to be explored. Predicted to be regulated by miR-126, TOM1 (target of Myb1) has been shown to interact with Toll-interacting protein, forming a complex to regulate endosomal trafficking of ubiquitinated proteins. TOM1 has also been proposed as a negative regulator of IL-1beta and TNF-alpha-induced signaling pathways. MiR-126 is highly expressed in the lung, and we now show for the first time differential expression of miR-126 in CF versus non-CF airway epithelial cells both in vitro and in vivo. MiR-126 downregulation in CF bronchial epithelial cells correlated with a significant upregulation of TOM1 mRNA, both in vitro and in vivo when compared with their non-CF counterparts. Introduction of synthetic pre-miR-126 inhibited luciferase activity in a reporter system containing the full length 3\\'-untranslated region of TOM1 and resulted in decreased TOM1 protein production in CF bronchial epithelial cells. Following stimulation with LPS or IL-1beta, overexpression of TOM1 was found to downregulate NF-kappaB luciferase activity. Conversely, TOM1 knockdown resulted in a significant increase in NF-kappaB regulated IL-8 secretion. These data show that miR-126 is differentially regulated in CF versus non-CF airway epithelial cells and that TOM1 is a miR-126 target that may have an important role in regulating innate immune responses in the CF lung. To our knowledge, this study is the first to report of a role for TOM1 in the TLR2\\/4 signaling pathways and the first to describe microRNA involvement in CF.

  6. Theory of mind broad and narrow: reasoning about social exchange engages ToM areas, precautionary reasoning does not.

    Science.gov (United States)

    Ermer, Elsa; Guerin, Scott A; Cosmides, Leda; Tooby, John; Miller, Michael B

    2006-01-01

    Baron-Cohen (1995) proposed that the theory of mind (ToM) inference system evolved to promote strategic social interaction. Social exchange--a form of co-operation for mutual benefit--involves strategic social interaction and requires ToM inferences about the contents of other individuals' mental states, especially their desires, goals, and intentions. There are behavioral and neuropsychological dissociations between reasoning about social exchange and reasoning about equivalent problems tapping other, more general content domains. It has therefore been proposed that social exchange behavior is regulated by social contract algorithms: a domain-specific inference system that is functionally specialized for reasoning about social exchange. We report an fMRI study using the Wason selection task that provides further support for this hypothesis. Precautionary rules share so many properties with social exchange rules--they are conditional, deontic, and involve subjective utilities--that most reasoning theories claim they are processed by the same neurocomputational machinery. Nevertheless, neuroimaging shows that reasoning about social exchange activates brain areas not activated by reasoning about precautionary rules, and vice versa. As predicted, neural correlates of ToM (anterior and posterior temporal cortex) were activated when subjects interpreted social exchange rules, but not precautionary rules (where ToM inferences are unnecessary). We argue that the interaction between ToM and social contract algorithms can be reciprocal: social contract algorithms requires ToM inferences, but their functional logic also allows ToM inferences to be made. By considering interactions between ToM in the narrower sense (belief-desire reasoning) and all the social inference systems that create the logic of human social interaction--ones that enable as well as use inferences about the content of mental states--a broader conception of ToM may emerge: a computational model embodying

  7. Social Infrastructure to Integrate Science and Practice: the Experience of the Long Tom Watershed Council

    Directory of Open Access Journals (Sweden)

    Rebecca L. Flitcroft

    2009-12-01

    Full Text Available Ecological problem solving requires a flexible social infrastructure that can incorporate scientific insights and adapt to changing conditions. As applied to watershed management, social infrastructure includes mechanisms to design, carry out, evaluate, and modify plans for resource protection or restoration. Efforts to apply the best science will not bring anticipated results without the appropriate social infrastructure. For the Long Tom Watershed Council, social infrastructure includes a management structure, membership, vision, priorities, partners, resources, and the acquisition of scientific knowledge, as well as the communication with and education of people associated with and affected by actions to protect and restore the watershed. Key to integrating science and practice is keeping science in the loop, using data collection as an outreach tool, and the Long Tom Watershed Council's subwatershed enhancement program approach. Resulting from these methods are ecological leadership, restoration projects, and partnerships that catalyze landscape-level change.

  8. TOMS as a monitor of the ultraviolet radiation environment: applications to photobiology

    International Nuclear Information System (INIS)

    Frederick, J.E.

    1987-01-01

    The flux of biologically relevant ultraviolet radiation that reaches the surface of the Earth varies with the ozone amount, surface reflectivity, and cloudcover. The Total Ozone Mapping Spectrometer (TOMS) provides information relevant to all three items. A recent application of satellite-based ozone measurements has been to develop climatologies of the biologically significant UV-B radiation reaching the Earth's surface. A growing body of research suggests that UV-B radiation tends to suppress the immune system of laboratory mice. At tropical latitudes, it is likely that parasitical diseases develop most readily in people who have experienced immune system suppression from UV-B exposure. The computed distribution of surface radiation combined with information on disease incidence may clarify the role of UV-B as a suppressor of the human immune system. TOMS used in conjunction with radiative transfer calculations can provide information of relevance in photobiology

  9. Santo Tomás y los demás

    Directory of Open Access Journals (Sweden)

    Alfonso Rincón

    1988-10-01

    Full Text Available La filosofia del medioevo. VIII Coloquio de la Sociedad Colombiana de Filosofia. J.A. Díaz, J.P. Margot, A.L. Gómez, E. Lákatos, A. Cárdenas, G. Soto, D. Herrera, A. Papacchini, J. Zabalza. Biblioteca Colombiana de Filosofía, Universidad de Santo Tomás, Bogotá, 1987, 138 págs.

  10. O tom, tshto ushlo : [luuletused] / Aleksander Suuman ; Lühibiograafia: T. L. [Toomas Liiv

    Index Scriptorium Estoniae

    Suuman, Aleksander, 1927-2003

    1999-01-01

    Sisu: O tom, tshto ushlo ; "Gde-to dolzhno zhe bõt stshastje..." ; "Serõje lessa..." ; Zholtogolovõ ; "Teh iv serebristõh nelzja oboiti..." ; "Vzroslõje vkladtshinu pili..." ; "U nas tut, za Giperborejem..." / tlk. Svetlan Semenenko ; Odno hotshu skazat ; Los idjot / tlk. Boris Baljasnõi.Orig.: "Kusagil peab olema õnn..." ; Kullerkupud ; "Ei hõbepajust ma mööduda saand..." ; "Meil siin Hüperboreas..." ;

  11. Die soektog na 'n mitiese wêreld: Equatoria van Tom Dreyer

    OpenAIRE

    RENDERS, Luc

    2010-01-01

    Equatoria (2006) is Tom Dreyer's third novel. It is a historical novel, which is situated in 1912 in the Belgian Congo. Equatoria makes use of an age old narrative pattern, namely the quest, and combines historical and mythological sources. Dreyer loosely bases his novel on the expedition of Herbert Lang and James Chapin to the Congo from 1909 to 1915. With the historical facts Dreyer creates a fictional world with strongly mythical overtones. The hunt for the elusive okapi is the focal point...

  12. Molecular biology and riddle of cancer: the ‘Tom & Jerry’ show

    Directory of Open Access Journals (Sweden)

    Md. Al Mamun

    2011-11-01

    Full Text Available From the conventional Bird’s eye, cancer initiation and metastasis are generally intended to be understood beneath the light of classical clonal genetic, epigenetic and cancer stem cell model. But inspite decades of investigation, molecular biology has shown hard success to give Eagle’s eye in unraveling the riddle of cancer. And it seems, tiring Tom runs in vague behind naughty Jerry.

  13. Spatial Politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead

    OpenAIRE

    Elham Kazemi; Mohsen Hanif

    2017-01-01

    http://dx.doi.org/10.5007/2175-8026.2017v70n1p287 This article examines the notion of spatial politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead. The two courtiers enter the politically convulsive world of Hamlet, where no legitimate power structure takes hold of the state. Their regularized political rationality ceases to apply to the world; reality violates the empirical knowledge — emplacements, geographical and spiritual directions, and generally identity — of Rosencrant...

  14. El procesamiento informático de los materiales del Atlas Lingüístico de la Península Ibérica de Tomás Navarro Tomás

    OpenAIRE

    García Mouton, Pilar

    2010-01-01

    Estas páginas dan noticia de la puesta en marcha de un proyecto intramural del CSIC para elaborar y editar definitivamente, en soporte informático, los materiales del Atlas Lingüístico de la Península Ibérica, que Tomás Navarro Tomás dirigió en la primera mitad del siglo XX.

  15. How Tom Moon's research highlighted the question of glucose tolerance in carnivorous fish.

    Science.gov (United States)

    Polakof, S; Panserat, S

    2016-09-01

    Fifteen years ago, Tom Moon wrote a review on this journal in order to propose some explanations to the exacerbated glycaemic response after a glucose load or a carbohydrate meal intake observed in fish, the so-called intolerance to glucose. Before, but in most of cases after this paper, several laboratories worldwide started to make important efforts in order to better understand this strange phenotype observed in fish and that so far seemed to belong to diabetic humans only. Tom had been worked on fish metabolism for at least 30years when he proposed that mini-review and the paths opened by him in 2001 were followed by tens of fish researchers, making this paper a breaking point on the field. Fifteen years later, we propose not only to have a look to the answers given to the questions rose in that paper, but also to summarize how his career over all these years impacted the domain of glucose metabolism in fish. In the review, we will show how Tom Moon analysed at different levels (from genes up to the whole organism), using distinct experimental tools (cells, hormone or glucose injection, pumps, drugs) the questions of glucose metabolism, tolerance and nutrition in fish species. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Performance and Carcass characteristics of broad breasted bronze toms fed radappertized Diet

    International Nuclear Information System (INIS)

    Farag, El-Din.M.H.; Mohamed, F.A.

    1999-01-01

    The effect of irradiated complete diets at dose level of 25 KGy was studied in broad breasted bronze tome evaluating their growing performances as well as characteristics of the carcasses. Two experimental groups received irradiated and non irradiated diets for 18 weeks (from the 5 t h to the 23 r d week of age). Four toms per treatment at the age of 23 weeks were slaughtered and the carcass was dissected. Radappertized diets improved body weight gain, feed consumption and feed conversion and reduced mortality rate. No significant differences were observed between toms fed processed and non processed diets on carcasses components, while the gizzard weight was greater for those fed the processed diets. Dressing and drawn weights in toms fed processed diets were 3% higher than in those fed non processed diets. The results suggest that sterilization of turkeys feed may have a beneficial effect on the body weight and deed conversion of turkeys consuming these diets without harmful effect on the bird

  17. Constructing a coherent long-term global total ozone climatology from the BUV, MFR, and SBUV/TOMS data sets

    International Nuclear Information System (INIS)

    Ellis, J.S.; Luther, F.M.

    1986-02-01

    The backscatter ultraviolet spectrometer (BUV) aboard the NIMBUS 4 satellite provided global ozone data until mid-1977. The Total Ozone Mapping Spectrometer (TOMS) and Solar Backscattered Ultraviolet (SBUV) instrument aboard the NIMBUS 7 satellite began providing global ozone in November 1978. The only satellite derived global total ozone data available between the termination of the BUV data and the startup of the SBUV/TOMS data is that from the Multichannel Filter Radiometer (MFR) instrument aboard the Defense Meteorological Satellite Program (DMSP) series of satellites. The MFR and the SBUV/TOMS data are compared during the data overlap period in order to determine how well the MFR data might be used to represent the SBUV/TOMS and BUV data during the data gap period. 5 refs., 3 figs., 3 tabs

  18. Occurrence of ozone anomalies over cloudy areas in TOMS version-7 level-2 data

    Directory of Open Access Journals (Sweden)

    X. Liu

    2003-01-01

    Full Text Available This study investigates anomalous ozone distributions over cloudy areas in Nimbus-7 (N7 and Earth-Probe (EP TOMS version-7 data and analyzes the causes for ozone anomaly formation. A 5°-longitude by 5°-latitude region is defined to contain a Positive Ozone Anomaly (POA or Negative Ozone Anomaly (NOA if the correlation coefficient between total ozone and reflectivity is > 0.5 or -0.5. The average fractions of ozone anomalies among all cloud fields are 31.8 ± 7.7% and 35.8 ± 7.7% in the N7 and EP TOMS data, respectively. Some ozone anomalies are caused by ozone retrieval errors, and others are caused by actual geophysical phenomena. Large cloud-height errors are found in the TOMS version-7 algorithm in comparison to the Temperature Humidity Infrared Radiometer (THIR cloud data. On average, cloud-top pressures are overestimated by ~200 hPa (THIR cloud-top pressure 200 hPa for high-altitude clouds and underestimated by ~150 hPa for low-altitude clouds (THIR cloud-top pressure > 750 hPa. Most tropical NOAs result from negative errors induced by large cloud-height errors, and most tropical POAs are caused by positive errors due to intra-cloud ozone absorption enhancement. However, positive and negative errors offset each other, reducing the ozone anomaly occurrence in TOMS data. Large ozone/reflectivity slopes for mid-latitude POAs show seasonal variation consistent with total ozone fluctuation, indicating that they result mainly from synoptic and planetary wave disturbances. POAs with an occurrence fraction of 30--60% occur in regions of marine stratocumulus off the west coast of South Africa and off the west coast of South America. Both fractions and ozone/reflectivity slopes of these POAs show seasonal variations consistent with that in the tropospheric ozone. About half the ozone/reflectivity slope can be explained by ozone retrieval errors over clear and cloudy areas. The remaining slope may result from there being more ozone production

  19. Effect of phosphate treatments on microbiological, physicochemical changes of spent hen muscle marinated with Tom Yum paste during chilled storage.

    Science.gov (United States)

    Wongwiwat, Pirinya; Wattanachant, Saowakon; Siripongvutikorn, Sunisa

    2010-06-01

    This research aimed to study the effect of phosphate on quality of ready-to-cook spent hen muscle marinated with Tom Yum paste, a famous Thai food made from chilli, lime leaves and garcinia (pH 2.5-2.9). The effects of phosphate treatments (phosphate types, soaking time, and phosphate concentration) on physical characteristics of spent hen muscle in high acid condition were investigated. Quality changes of muscles pretreated with or without phosphate and marinated with Tom Yum paste were determined during storage at 4 degrees C for 30 days. The acidified muscle pretreated with 40 g L(-1) sodium tripolyphosphate for 10 h had the highest marinade absorption, and the lowest cooking loss and shear force among all treatment samples. Microstructures of acidified muscle pretreated with and without sodium tripolyphosphate showed significant swelling with larger fibre diameter. Phosphate pretreatment had no influence on cooking loss, shear force and thiobarbituric acid reactive substance values of Tom Yum marinated muscle during storage. Tom Yum marination with phosphate pretreatment caused a higher increase in psychrophilic bacteria compared to that of marinating without phosphate. Phosphate pretreatment could not improve the physical quality of Tom-Yum marinated spent hen muscle and affected the antimicrobial property of Tom-Yum marinade, resulting in a reduction of shelf-life of the marinated muscle from 30 days to 20 days. Copyright (c) 2010 Society of Chemical Industry.

  20. Investigating the genetic basis of theory of mind (ToM): the role of catechol-O-methyltransferase (COMT) gene polymorphisms.

    Science.gov (United States)

    Xia, Haiwei; Wu, Nan; Su, Yanjie

    2012-01-01

    The ability to deduce other persons' mental states and emotions which has been termed 'theory of mind (ToM)' is highly heritable. First molecular genetic studies focused on some dopamine-related genes, while the genetic basis underlying different components of ToM (affective ToM and cognitive ToM) remain unknown. The current study tested 7 candidate polymorphisms (rs4680, rs4633, rs2020917, rs2239393, rs737865, rs174699 and rs59938883) on the catechol-O-methyltransferase (COMT) gene. We investigated how these polymorphisms relate to different components of ToM. 101 adults participated in our study; all were genetically unrelated, non-clinical and healthy Chinese subjects. Different ToM tasks were applied to detect their theory of mind ability. The results showed that the COMT gene rs2020917 and rs737865 SNPs were associated with cognitive ToM performance, while the COMT gene rs5993883 SNP was related to affective ToM, in which a significant gender-genotype interaction was found (p = 0.039). Our results highlighted the contribution of DA-related COMT gene on ToM performance. Moreover, we found out that the different SNP at the same gene relates to the discriminative aspect of ToM. Our research provides some preliminary evidence to the genetic basis of theory of mind which still awaits further studies.

  1. Ratio superior, ratio inferior y el agustinismo de Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Moya Cañas, Patricia

    2013-12-01

    Full Text Available This article discusses Aquinas’ reception of the Augustinian distinction between ratio inferior and superior. Though not a central aspect of Aquinas’ thought, it is a signifi cant pointer to the presence of Augustinian patterns of thought in a non-theological part of his work. After a general survey of the presence of this distinction in the opera omnia of Aquinas, his use of this topic in some specific instances is discussed: the distinction between contemplative and active life, the division of human faculties, and the moral problem of peevish delight.El artículo discute la recepción que hace Tomás de Aquino de la distinción agustiniana entre razón superior e inferior. Si bien no se trata de uno de los tópicos centrales de la doctrina tomasiana, es un elemento significativo a la hora de considerar dentro de la obra de Tomás la presencia de patrones agustinianos de pensamiento que no sean primordialmente teológicos. Tras discutir de modo general la presencia de esta distinción en la obra del aquinate, y los estudios previos sobre este binomio, se procede a discutir su uso por parte de Tomás de Aquino ante tres problemas específicos: la distinción entre géneros de vida, la división de las facultades humanas, y el problema moral de la delectación morosa.

  2. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    Directory of Open Access Journals (Sweden)

    Eli Løfaldli

    2017-06-01

    Full Text Available As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749. In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly felt throughout the novel, but through a variety of means, ‘The History of Tom Jones, A Foundling’ is also distinctly marked as being under his control and ownership. The two adaptations of Fielding’s novel, a 1963 film and a 1997 television series, both retain the figure of the author-narrator, but differ greatly in their handling of this device and its consequent thematic ramifications. Although the 1963 film de-emphasises Henry Fielding’s status as proprietor of the story, the author-narrator as represented in the film’s voiceover commentary is a figure of authority and authorial control. In contrast, the 1997 adaptation emphasises Fielding’s ownership of the narrative and even includes the author-narrator as a character in the series, but this ownership is undermined by the irreverent treatment to which he is consistently subjected. The representations of Henry Fielding in the form of the author-narrator in both adaptations are not only indicative of shifting conceptions of authorship, but also of the important interplay between authorship, ownership and adaptation more generally.

  3. Reciclando a Tropicália: Tom Zé e o lixo lógico

    Directory of Open Access Journals (Sweden)

    Paula Oliveira Campos Augusto

    2015-06-01

    Full Text Available http://dx.doi.org/10.5007/2176-8552.2016n20p111 Este artigo tem como objetivo apresentar e analisar a tese de Tom Zé sobre a Tropicália, presente em seu disco Tropicália lixo lógico, lançado em 2012. Primeiramente, destacam-se duas características importantes da música popular brasileira, que ajudam a entender a possibilidade de um disco--tese: além de ser definida como um “campo dialogal” (1, a música popular brasileira é dotada de uma “malha de permeabilidades”, pelo modo como a alta cultura se cruza com produções populares, tendo como resultado a “leveza” (2. Em seu álbum, Tom Zé não apenas assume o protagonismo da interpretação da Tropicália, mas, também, desloca a antropofagia do centro interpretativo dessa manifestação artística e cultural brasileira. Nesse sentido, o disco é compreendido, levando-se em conta tanto seus aspectos físicos quanto simbólicos, a partir do que Walter Moser denomina de reciclagem cultural, uma vez que Tom Zé processa a inclusão de “restos” e “dejetos” no espaço cultural e artístico. Ademais, com a reciclagem do lixo lógico, o espaço hegemônico incorpora materiais culturais de outras procedências, colocando-os em diálogo.

  4. A study on the growth of compound semiconductor single crystal by TOM technique

    International Nuclear Information System (INIS)

    Kim, H.C.; Kwon, S.I.; Chung, M.K.; Chang, J.S.

    1981-01-01

    This paper describes the merit of the HgI 2 single crystals obtained by solution growth, 2- and 3-region temperature growth, and temperature oscillation growth for soft γ-ray detectors which can be operated at room temperature. Special efforts are put on the design, construction, and operation of the TOM (Temperature Oscillation Method) single crystal growing furnace. Experimental results show that HgI 2 detectors fabricated by vapour phase growth method usually exhibit sufficient enough detector characteristics for soft γ-ray spectrometry. However, further investigation should be carried out to eliminate detector deterioration due to polarization effect. (author)

  5. Ejercicios y penitencia en la obra de Tomé de Jesus

    Directory of Open Access Journals (Sweden)

    Eduardo Javier Alonso Romo

    2009-01-01

    Full Text Available The present essay aims at approaching the classic Trabalhos de Jesus, posthumous work of the Augustinian friar of sixteenth century Tomé de Jesus, through a perspective of exercises of penance, inside the most extended field of the spiritual exercises. Questions are analysed like the methodology, the prayer practices and of spiritual discernment, the dualism between inner penitence and exterior penitences, as well as the advices to break down the temptations, and the uses for the examination of conscience and the confession. The author is placed in relation with other peninsular authors of that time specially saint Ignatius of Loyola.

  6. Spatial Politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead

    OpenAIRE

    Kazemi, Elham; Hanif, Mohsen

    2017-01-01

     http://dx.doi.org/10.5007/2175-8026.2017v70n1p287This article examines the notion of spatial politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead. The two courtiers enter the politically convulsive world of Hamlet, where no legitimate power structure takes hold of the state. Their regularized political rationality ceases to apply to the world; reality violates the empirical knowledge — emplacements, geographical and spiritual directions, and generally identity — of Rosencrantz an...

  7. Empathy, ToM, and self-other differentiation: an fMRI study of internal states.

    Science.gov (United States)

    Reniers, Renate L E P; Völlm, Birgit A; Elliott, Rebecca; Corcoran, Rhiannon

    2014-02-01

    This study used functional magnetic resonance imaging to examine the neural substrates of empathy, Theory of Mind (ToM), and self-other differentiation involved in the adaptive understanding of people's internal states. Three conditions were distinguished in both sad and neutral (no obvious emotion) contexts. The empathy condition involved imagining what another person is feeling while the more cognitively loaded ToM condition involved imagining what would make another person feel better. The self-reference condition required participants to imagine how they would feel in someone else's situation. Areas previously implicated in empathy, ToM, and self-other differentiation were identified within the different conditions, regardless of emotional context. Specifically, the frontal and temporal poles responded more strongly for ToM than for empathy. The self-reference condition was associated with stronger dorsolateral prefrontal response than the empathy condition, while the reverse comparison revealed a stronger role for right frontal pole. Activations in frontal pole and orbitofrontal cortex were shared between the three conditions. Contrasts of parameter estimates demonstrated modulation by emotional context. The findings of common and differential patterns of responding observed in prefrontal and temporal regions suggest that within the social cognition network empathy, ToM and self-other differentiation have distinct roles that are responsive to context.

  8. TOMS/Earth-Probe Total Ozone Aerosol Index UV-Reflectivity UV-B Erythemal Irradiance Daily L3 Global 1x1.25 deg V008

    Data.gov (United States)

    National Aeronautics and Space Administration — The Total Ozone Mapping Spectrometer (TOMS) version 8 daily global gridded data consist of total column ozone, aerosol index, Lambertian effective surface...

  9. Plant nutritional status modulates glutamine synthetase levels in ripe tomatoes (Solanum lycopersicum cv. Micro-Tom).

    Science.gov (United States)

    Scarpeci, Telma E; Marro, Martin L; Bortolotti, Santiago; Boggio, Silvana B; Valle, Estela M

    2007-02-01

    Tomato (Solanum lycopersicum) fruit ripening implies that chloroplastic proteins are degraded and new proteins are synthesized. Supplementary nutrition is frequently required when tomato plants begin to fruit and continues until the end of the plant's life cycle. Ammonium assimilation is crucial in these fruit maturation and ripening processes. Glutamine synthetase (GS; EC 6.3.1.2), the main ammonium-fixing enzyme in plants, could not be detected in red fruits of several tomato varieties when growing under standard nutrition. In this paper, we analyze the influence of the nutritional status on the ammonium assimilation capacity of ripe tomato (cv. Micro-Tom) fruit. For this purpose, GS expression and protein profiles were followed in mature green and red fruits harvested from plants grown under standard or supplemented nutrition. Under standard nutrient regime (weekly supplied with 0.5 x Hoagland solution) GS activity was found in chloroplasts (GS2) of mature green fruits, but it was not detected either in the chromoplasts or in the cytosol of red fruits. When plants were shifted to a supplemented nutritional regime (daily supplied with 0.5 x Hoagland solution), GS was found in red fruits. Also, cytosolic transcripts (gs1) preferentially accumulated in red fruits under high nutrition. These results indicate that mature green Micro-Tom fruits assimilate ammonia through GS2 under standard nutrition, while ripe red fruits accumulate GS1 under high nutrition, probably in order to assimilate the extra N-compounds made available through supplemented nutrition.

  10. Estimation of surface UV levels based on Meteor-3/TOMS ozone data

    Energy Technology Data Exchange (ETDEWEB)

    Borisov, Y A [Central Aerological Observatory, Moscow (Russian Federation); Geogdzhaev, I V [Moscow Inst. of Physics and Technology, Moscow (Russian Federation); Khattatov, V U [Central Aerological Observatory, Moscow (Russian Federation)

    1996-12-31

    The major consequence of ozone layer depletion for the environment is an increase of harmful ultraviolet (UV) radiation on the Earth surface and in the upper ocean. This implies the importance of environmental UV monitoring. Since the direct global monitoring is not currently possible, indirect estimations of surface UV levels may be used based on satellite ozone data (Madronich, S. 1992). Total Ozone Mapping Spectrometer (TOMS) on board the METEOR-3 satellite provided regular set of data for such estimates. During the time of its operation (August, 1991 - December, 1994) the instrument registered several ozone hole events over Antarctica, when ozone levels dropped by as much as 60 % from their unperturbed values. Probably even more alarming ozone depletions were observed over highly populated regions of middle latitudes of northern hemisphere. Radiative transfer modeling was used to convert METEOR-3/TOMS daily ozone values into regional and global maps of biologically active UV. Calculations demonstrate the effect on surface UV levels produced by ozone hole over Antarctica and ozone depletions over the territory of Russia (March, 1994). UV contour lines deviate from the normal appearance which is determined by growing southward solar elevation. UV contour lines are almost perpendicular to the ozone ones in the ozone depletions areas. The 30 % ozone depletion, over Siberia caused more than 30 % increase in noontime erythemal UV levels, which is equivalent to 10-15 degrees southward latitude displacement. Higher UV radiation increases were found in ozone hole over South America (October 1992) equivalent to about 20 degrees southward displacement

  11. Lope y Boccalini: Tres sonetos de Tomé de Burguillos

    Directory of Open Access Journals (Sweden)

    Arellano, Ignacio

    2012-12-01

    Full Text Available The article analyzes three sonnets of Lope against Traiano Boccalini included in the Rhymes of Tomé de Burguillos, showing the need to compare the Lope´s text with the italian original version of Ragguagli di Parnaso, not with spanish translation of Perez de Sousa, because in this translation are deleted essential passages to understand the game of wit of Lope. These three sonnets are a good example of the complexity of this exercise of conceptism in Lope, whose poetry can not be described as plain, simple and clear: it is a difficult poetry full of games, intertextual allusions and references that should be clarified applying the type of appropiate reading.Se analizan tres sonetos de Lope contra el italiano Traiano Boccalini, incluidos en las Rimas de Tomé de Burguillos, mostrando la necesidad de comparar el texto de Lope con el de los Ragguagli di Parnaso, en su versión original italiana, y no en la traducción de Perez de Sousa, que elimina pasajes necesarios para entender los juegos de Lope. Estos tres sonetos son buena muestra de la complejidad que puede tener este ejercicio de agudeza de Lope, cuya poesía no se puede calificar sin más de llana, sencilla o clara: es una poesía conceptista llena de juegos, alusiones y referencias intertextuales que deben ser aclaradas si se quiere aplicar a estos poemas el tipo de lectura que exigen.

  12. Secret Guilt of an Artist: The Real Inspector Hound and Tom Stoppard’s Political Voice

    Directory of Open Access Journals (Sweden)

    Kevin Drzakowski

    2015-12-01

    Full Text Available Tom Stoppard once famously proclaimed his guilt that art is unimportant. The character Moon from Stoppard’s early farce The Real Inspector Hound presents surprising evidence that Stoppard’s view of art in his early years as a playwright may have been more complex than he let on. The circumstances behind Moon’s journey into the very art he criticizes are not unlike Tom Stoppard’s foray into politically conscious drama. Moon desperately wants the thriller he is reviewing to mean more than it really does. His wish becomes a reality when a third party, Puckeridge, forcibly pulls Moon into the fantasy. Like Moon, Stoppard had a fantasy, a dream-world in which art has the power to enact social change. Stoppard was unwilling or unable to act on that desire alone, until his own Puckeridge, an artist and dissident named Victor Fainberg, compelled him to act on his dream and merge art with politics.Keywords: Stoppard, The Real Inspector Hound, Fainberg, art, politics

  13. The Effect of New Ozone Cross Sections Applied to SBUV and TOMS Retrievals

    Science.gov (United States)

    McPeters, Richard D.; Labow, Gordon J.

    2010-01-01

    The ozone cross sections as measured by Bass and Paur have been used for processing of SBUV and TOMS data since 1986. While these cross sections were a big improvement over those previously available, there were known minor problems with accuracy for wavelengths longward of 330 nm and with the temperature dependance. Today's requirements to separate stratospheric ozone from tropospheric ozone and for the derivation of minor species such as BrO and N02 place stringent new requirements on the accuracy needed. The ozone cross section measurements of Brion, Daumont, and Malicet (BDM) are being considered for use in UV-based ozone retrievals. They have much better resolution, an extended wavelength range, and a more consistent temperature dependance. Tests show that BDM retrievals exhibit lower retrieval residuals in the satellite data; i.e., they explain our measured atmospheric radiances more accurately. Total column ozone retrieved by the TOMS instruments is about 1.5% higher than before. Ozone profiles retrieved from SBUV using the new cross sections are lower in the upper stratosphere and higher in the lower stratosphere and troposphere.

  14. Tomé, futuro turístico y renacer industrial

    Directory of Open Access Journals (Sweden)

    Carol Andaluz Sandoval

    2003-01-01

    Full Text Available La ciudad de Tomé, ubicada en la ribera N.E. de la bahía de Talcahuano, distante a sólo 32 kilómetros al norte del Gran Concepción, se ha desarrollado económica y territorialmente por los diferentes aconteceres que le ha correspondido presenciar durante la historia. Es así como encontramos vestigios de la grandeza de su apogeo pesquero, portuario, molinero, vitivinícola y textil, tanto en el ordenamiento de su trama urbana como en obras arquitectónicas que muestran un claro reflejo de las inmigraciones extranjeras que se vieron atraídas por esta próspera ciudad, que nació como caleta de pescadores y se transformó en un centro industrial de gran importancia nacional. Tal fue su significancia dentro de las zonas costeras del país que en el año 1858, el Congreso Nacional declaró a Tomé Puerto Mayor, lo que se tradujo en un aumento importante de la población, la industria y las actividades que esto conllevaba.

  15. Statecraft and Leadership in Europe: The Case of Tomáš Garrigue Masaryk

    Directory of Open Access Journals (Sweden)

    Tomas Tatinec

    2014-09-01

    Full Text Available Born to Slovaco-German-Czech poor servants, with no burning interest in politics until adult age, who even came to be called the enemy of the nation, Tomáš Masaryk managed to introduce the first Czechoslovak state on the world map in 1918, through tireless advocacy carried out (literally all around the world during the Great War, and the subsequent guidance in the newly formed republic. He was unanimously elected President four times and served in this function for eighteen years (1918-1935. Tomáš Masaryk was not a product of circumstances, but their producer and skillful employer. He showed himself particularly adroit in overcoming the against-all-odds situations, as well as the ‘regular’ crisis ones. Initially isolated, resourceless, and repudiated by his own people, he managed to unite them and to make them join his idea and struggle for a project aiming for common good. Such a CV seems remarkably appropriate for a potential leader in Europe’s most advanced uniting project, the EU (European Union. Considering the 100th anniversary of the beginning of Masaryk’s state-building journey, as well as the current crisis debates in the EU, it seems appropriate to remind ourselves of a leader with a vision, determination, skill, and principles. The EU may need precisely those to stay united.

  16. Estimation of surface UV levels based on Meteor-3/TOMS ozone data

    Energy Technology Data Exchange (ETDEWEB)

    Borisov, Y.A. [Central Aerological Observatory, Moscow (Russian Federation); Geogdzhaev, I.V. [Moscow Inst. of Physics and Technology, Moscow (Russian Federation); Khattatov, V.U. [Central Aerological Observatory, Moscow (Russian Federation)

    1995-12-31

    The major consequence of ozone layer depletion for the environment is an increase of harmful ultraviolet (UV) radiation on the Earth surface and in the upper ocean. This implies the importance of environmental UV monitoring. Since the direct global monitoring is not currently possible, indirect estimations of surface UV levels may be used based on satellite ozone data (Madronich, S. 1992). Total Ozone Mapping Spectrometer (TOMS) on board the METEOR-3 satellite provided regular set of data for such estimates. During the time of its operation (August, 1991 - December, 1994) the instrument registered several ozone hole events over Antarctica, when ozone levels dropped by as much as 60 % from their unperturbed values. Probably even more alarming ozone depletions were observed over highly populated regions of middle latitudes of northern hemisphere. Radiative transfer modeling was used to convert METEOR-3/TOMS daily ozone values into regional and global maps of biologically active UV. Calculations demonstrate the effect on surface UV levels produced by ozone hole over Antarctica and ozone depletions over the territory of Russia (March, 1994). UV contour lines deviate from the normal appearance which is determined by growing southward solar elevation. UV contour lines are almost perpendicular to the ozone ones in the ozone depletions areas. The 30 % ozone depletion, over Siberia caused more than 30 % increase in noontime erythemal UV levels, which is equivalent to 10-15 degrees southward latitude displacement. Higher UV radiation increases were found in ozone hole over South America (October 1992) equivalent to about 20 degrees southward displacement

  17. Polypeptide Translocation Through the Mitochondrial TOM Channel: Temperature-Dependent Rates at the Single-Molecule Level.

    Science.gov (United States)

    Mahendran, Kozhinjampara R; Lamichhane, Usha; Romero-Ruiz, Mercedes; Nussberger, Stephan; Winterhalter, Mathias

    2013-01-03

    The TOM protein complex facilitates the transfer of nearly all mitochondrial preproteins across outer mitochondrial membranes. Here we characterized the effect of temperature on facilitated translocation of a mitochondrial presequence peptide pF1β. Ion current fluctuations analysis through single TOM channels revealed thermodynamic and kinetic parameters of substrate binding and allowed determining the energy profile of peptide translocation. The activation energy for the on-rate and off-rate of the presequence peptide into the TOM complex was symmetric with respect to the electric field and estimated to be about 15 and 22 kT per peptide. These values are above that expected for free diffusion of ions in water (6 kT) and reflect the stronger interaction in the channel. Both values are in the range for typical enzyme kinetics and suggest one process without involving large conformational changes within the channel protein.

  18. Technical Note: Adjoint formulation of the TOMCAT atmospheric transport scheme in the Eulerian backtracking framework (RETRO-TOM)

    Science.gov (United States)

    Haines, P. E.; Esler, J. G.; Carver, G. D.

    2014-06-01

    A new methodology for the formulation of an adjoint to the transport component of the chemistry transport model TOMCAT is described and implemented in a new model, RETRO-TOM. The Eulerian backtracking method is used, allowing the forward advection scheme (Prather's second-order moments) to be efficiently exploited in the backward adjoint calculations. Prather's scheme is shown to be time symmetric, suggesting the possibility of high accuracy. To attain this accuracy, however, it is necessary to make a careful treatment of the "density inconsistency" problem inherent to offline transport models. The results are verified using a series of test experiments. These demonstrate the high accuracy of RETRO-TOM when compared with direct forward sensitivity calculations, at least for problems in which flux limiters in the advection scheme are not required. RETRO-TOM therefore combines the flexibility and stability of a "finite difference of adjoint" formulation with the accuracy of an "adjoint of finite difference" formulation.

  19. Can REDD+ help the conservation of restricted-range island species? Insights from the endemism hotspot of São Tomé

    DEFF Research Database (Denmark)

    de Lima, Ricardo Faustino; Olmos, Fábio; Dallimer, Martin

    2013-01-01

    , using São Tomé Island (Democratic Republic of São Tomé and Príncipe) as a case study. We quantified the abundance of bird and tree species, and calculated the aboveground carbon stocks across a gradient of land-use intensity. We found a strong spatial congruence between carbon and the presence...

  20. Instituciones microfinancieras y cajas de ahorro en Santo Tomás Hueyotlipan, Puebla

    Directory of Open Access Journals (Sweden)

    Kristiano Raccanello

    2014-01-01

    Full Text Available La exigua presencia de los intermediarios financieros formales en los municipios rurales mexicanos impulsa el uso de tandas y solicitud de dinero a prestamistas, familiares o amigos. Las cajas de ahorro constituyen una alternativa a estos métodos tradicionales y aprovechan el capital social comunitario. Esta investigación, fundamentado en una muestra realizada en el municipio de Santo Tomás Hueyotlipan (Puebla, México, analiza los factores que impulsan la participación en las cajas de ahorro informales y su interacción con otros intermediarios financieros informales. Los resultados del modelo probit indican que la participación responde a la posibilidad de poder ahorrar atrayendo a aquellos individuos que no utilizan tandas, prestamistas o deudas con familiares o amigos.

  1. Radioecological monitoring of the Tom' river ecosystem within zone of nuclear fuel cycle plants influence

    International Nuclear Information System (INIS)

    Leonova, G.A.; Bobrov, V.A.; Malikov, Yu.I.; Mel'gunov, M.S.; Makarova, I.V.; Toropov, A.V.

    2005-01-01

    According to the results of 2000-2002 expeditions the estimation of radioactive contamination scales in water ecosystems within zone of Siberian Chemical Industrial Complex (SCC) influence was performed. The accumulation levels of short-lived artificial radionuclides in biota components of SCC technological channel (Romashka river), and spatial radionuclide distribution in biota of ecosystem of the Tom' and Ob' rivers at different distances from the local source have been determined using biochemical indication method. The most frequently occurring species of plants, filamentous green algae and fish were selected as indicator bioobjects for the monitoring. In spectrum of radioisotopes revealed in water plants, fish and water of the Romashka river there were determined twelve short-living isotopes that denoted continuing river burial. (author)

  2. Constructing Unfinalizability: A Subject Positioning Analysis of a Couple's Therapy Session Hosted by Tom Andersen.

    Science.gov (United States)

    Guilfoyle, Michael

    2018-03-08

    The notion of subject positions is a useful tool in thinking through therapeutic interactions. In this article, I discuss positioning as an everyday phenomenon, and highlight the relational and social power dynamics that shape the subject positions persons may inhabit. Analysis is presented of the positional dynamics that play out in the couple's therapy session facilitated by Tom Andersen. Analysis suggests that Andersen adopts a not-knowing, uncertain, and curious position, while constructing the couple as competent, unfinalizable persons able to negotiate the choice-points that arise in front of them. However, if subject positions are grounded in social power dynamics, the session leaves a particular question unanswered: How will these emergent positions take hold outside of the consulting room? © 2018 American Association for Marriage and Family Therapy.

  3. Issuing and Responding to Unusual Questions: A Conversation Analytic Account of Tom Andersen's Therapeutic Practice.

    Science.gov (United States)

    Smoliak, Olga; Le Couteur, Amanda; Quinn-Nilas, Christopher

    2018-03-08

    Tom Andersen is considered one of the key contributors to the development of postmodern practice. Little is known, however, about the ways in which his ideas and practices are routinely carried out in situ. We used Conversation Analysis (CA) to investigate a session of couple therapy facilitated by Andersen. We show how Andersen and client participants oriented to and addressed problems of understanding that occurred between them. The source of this trouble was Andersen's use of unusual question formulations. We offer preliminary evidence that such unusual formulations served particular interactional and institutional (i.e., therapeutic) functions in their local contexts of use. We conclude by considering some implications of this analysis-and of conversation analytic inquiry more generally-for the practice of family therapy. © 2018 American Association for Marriage and Family Therapy.

  4. Sarcoma de Kaposi en una paciente de Santo Tomé y Príncipe

    Directory of Open Access Journals (Sweden)

    Melba Elers Bandera

    2013-10-01

    Full Text Available Se presenta el caso clínico de una paciente que fue asistida en el Hospital General "Dr. Ayres Menezes" de la República Democrática de Santo Tomé y Príncipe, por presentar fiebre y lesiones en la piel, a la cual se le diagnosticó sarcoma de Kaposi asociado a la infección por el virus de inmunodeficiencia humana/sida. La evolución tórpida y el estadio tan avanzado de la enfermedad, así como la resistencia a los fármacos antirretrovirales, ocasionaron la muerte de la fémina

  5. Spatial Politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead

    Directory of Open Access Journals (Sweden)

    Elham Kazemi

    2017-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2017v70n1p287 This article examines the notion of spatial politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead. The two courtiers enter the politically convulsive world of Hamlet, where no legitimate power structure takes hold of the state. Their regularized political rationality ceases to apply to the world; reality violates the empirical knowledge — emplacements, geographical and spiritual directions, and generally identity — of Rosencrantz and Guildenstern. The previously defined functions of places, or heterotopias (in Foucauldian terms, are in a state of abeyance. Therefore, they are lost in the midst of the unknown sets of spatial relations; any sorts of intentional act evade them; and they die and vanish absurdly in a placeless place.

  6. Reuniones, dispersiones. Notas sobre ideas literarias de Tomás Segovia

    Directory of Open Access Journals (Sweden)

    Juan Pascual Gay

    2014-01-01

    Full Text Available Este artículo quiere dar cuenta de diferentes ideas expuestas por Tomás Segovia a lo largo de su oficio de escritor en ensayos, cuadernos de notas y entrevistas. Segovia no desarrolló un pensamiento unitario y sistemático, sino que, más bien, desarrolla esas ideas en diferentes contextos, textos y pretextos, pero esas ideas acaban por volver siem - pre a un ideario que otorga una cohesión insospechada en su obra. Además, muchas veces, sin decirlo, deja entrever la tradición literaria y cultural a la que se adscribe y que permea su obra entera.

  7. TOMATOMA Update: Phenotypic and Metabolite Information in the Micro-Tom Mutant Resource.

    Science.gov (United States)

    Shikata, Masahito; Hoshikawa, Ken; Ariizumi, Tohru; Fukuda, Naoya; Yamazaki, Yukiko; Ezura, Hiroshi

    2016-01-01

    TOMATOMA (http://tomatoma.nbrp.jp/) is a tomato mutant database providing visible phenotypic data of tomato mutant lines generated by ethylmethane sulfonate (EMS) treatment or γ-ray irradiation in the genetic background of Micro-Tom, a small and rapidly growing variety. To increase mutation efficiency further, mutagenized M3 seeds were subjected to a second round of EMS treatment; M3M1 populations were generated. These plants were self-pollinated, and 4,952 lines of M3M2 mutagenized seeds were generated. We checked for visible phenotypes in the M3M2 plants, and 618 mutant lines with 1,194 phenotypic categories were identified. In addition to the phenotypic information, we investigated Brix values and carotenoid contents in the fruits of individual mutants. Of 466 samples from 171 mutant lines, Brix values and carotenoid contents were between 3.2% and 11.6% and 6.9 and 37.3 µg g(-1) FW, respectively. This metabolite information concerning the mutant fruits would be useful in breeding programs as well as for the elucidation of metabolic regulation. Researchers are able to browse and search this phenotypic and metabolite information and order seeds of individual mutants via TOMATOMA. Our new Micro-Tom double-mutagenized populations and the metabolic information could provide a valuable genetic toolkit to accelerate tomato research and potential breeding programs. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  8. Construction and modelling of a thermoelectric oxide module (TOM) as a demonstrator - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Tomes, P.; Weidenkaff, A.

    2010-08-15

    The project aims at the development of better thermoelectric materials for the direct conversion of solar heat into electricity. The maximum output power P{sub max} and the efficiency {eta} of the conversion was measured on a series of four-leg thermoelectric oxide modules (TOM). The modules were constructed by combining two p-type (La{sub 1.98}Sr{sub 0.02}CuO{sub 4}) and two n-type (CaMn{sub 0.98}Nb{sub 0.02}O{sub 3}) thermoelements connected electrically in series and thermally in parallel. The temperature gradient {Delta}T was provided by a High-Flux Solar Simulator source (HFSS) which generates a spectrum similar to solar radiation. This project was intended to be a feasibility study for the utilization of high temperature solar heat, which could not previously be demonstrated due to the low temperature stability of conventional materials. The direct conversion was proven by this study. The measurements show an almost linear temperature profile along the thermoelectric legs. However, the maximum output power resulted in 88.8 mW for a TOM with a leg length of 5 mm at {Delta}T = 622 K and has yet to be optimized by improving the converter design and the applied materials. The highest conversion efficiency {eta} was found for a heat flux of 4 to 8 W cm{sup -2}. The dependence of {eta} on the leg length was studied as well as the influence of a graphite coating on the hot Al{sub 2}O{sub 3} surface on {Delta}T, P{sub max} and {eta}. (authors)

  9. Modeling the Effects of Connecting Side Channels to the Long Tom River, Oregon

    Science.gov (United States)

    Appleby, C.; McDowell, P. F.

    2015-12-01

    The lower Long Tom River is a heavily managed, highly modified stream in the southwestern Willamette Valley with many opportunities for habitat improvements and river restoration. In the 1940s and 1950s, the US Army Corps of Engineers dramatically altered this river system by constructing the Fern Ridge Dam and three, large drop structures, converting the River from a highly sinuous channel to a straight, channelized stream that is interrupted by these grade control structures, and removed the majority of the riparian vegetation. As a result, juvenile spring Chinook salmon are no longer found in the Watershed and the local population of coastal cutthroat trout face limited aquatic habitat. When the river was channelized, long sections of the historical channel were left abandoned on the floodplain. Reconnecting these historical channels as side channels may improve the quality and quantity of aquatic habitat and could allow fish passage around current barriers. However, such construction may also lead to undesirable threats to infrastructure and farmland. This study uses multiple HEC-RAS models to determine the impact of reconnecting two historical channels to the lower Long Tom River by quantifying the change in area of flood inundation and identifying infrastructure in jeapordy given current and post-restoration conditions for 1.5, 5, 10, and 25-year flood discharges. Bathymetric data from ADCP and RTK-GPS surveys has been combined with LiDAR-derived topographic data to create continuous elevation models. Several types of side channel connections are modeled in order to determine which type of connection will result in both the greatest quantity of accessible habitat and the fewest threats to public and private property. In the future, this study will also consider the change in the quantity of physical salmonid habitat and map the areas prone to sedimentation and erosion using CEASAR and PHABSIM tools.

  10. Fray Tomás de Torquemada, iconógrafo y promotor de las artes

    Directory of Open Access Journals (Sweden)

    Caballero Escamilla, Sonia

    2009-03-01

    Full Text Available In this study the author analyses the Inquisitor Torquemada’s role in two Dominican foundations: the monasteries of Santo Tomás in Ávila and Santa Cruz in Segovia. The historical context in which they emerged and their association with inquisitorial activities converted them into ideal supports for a message designed by this Dominican friar for the purpose of conveying the prestige of the Order and the involvement of the Monarchy in the struggle against heretics. He used the arts to convey a propagandistic message, adapting older iconographic formulas to his current needs, aimed at promoting the expulsion of the Jews.

    En este trabajo se analiza la ascendencia del inquisidor Torquemada sobre dos fundaciones, el convento de Santo Tomás de Ávila y el de Santa Cruz de Segovia. El contexto histórico en el que surgen y su vinculación con la actividad inquisitorial las convierte en soportes de un mensaje hábilmente diseñado por el fraile dominico en el que pone de manifiesto el prestigio de la Orden de Santo Domingo y la implicación de la Monarquía en la lucha antiherética. Aprovechando la eficacia propagandística del lenguaje plástico, no dudará en acudir a fórmulas iconográficas del pasado adaptándolas a su momento presente, creando el caldo de cultivo necesario para lograr su objetivo, la expulsión de los judíos.

  11. Mida teeb sinu organisatsioon, et olla keskkonnasõbralik? / Liis Elmi, Monika Kuzmina, Kairit Kolskar, Kristina Toms...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad: BEST-Esonia juhatuse liige Liisi Elmi, Rahvaliidu Noored juhatuse esimees Monika Kuzmina, Noored Sotsiaaldemokraadid president Kairit Kolskar, AIESEC president Kristina Toms, Eesti Psühholoogiaüliõpilaste Ühenduse juhatuse liige Andres Vegel

  12. Water quality study at the Congaree Swamp National monument of Myers Creek, Reeves Creek and Toms Creek. Technical report

    International Nuclear Information System (INIS)

    Rikard, M.

    1991-11-01

    The Congaree Swamp National Monument is one of the last significant near virgin tracts of bottom land hardwood forests in the Southeast United States. The study documents a water quality monitoring program on Myers Creek, Reeves Creek and Toms Creek. Basic water quality parameters were analyzed. High levels of aluminum and iron were found, and recommendations were made for further monitoring

  13. Toward the problem of oil and gas bearing capacity of the East Tom-Kolyvan structural zone (Western Siberia)

    International Nuclear Information System (INIS)

    Stolbova, N F; Maerkov, P O

    2014-01-01

    The vast depression in the east Tom-Kolyvan folded zone (West Siberia) has been identified by the geophysical data. The well which uncovered 4000 m deep profile of the Jurassic and Paleozoic deposits has been drilled. The relevance of the research is the oil/gas-bearing capacity evaluation of the discovered depression in this West Siberia area

  14. Factorial structure of the 'ToM Storybooks': A test evaluating multiple components of Theory of Mind.

    Science.gov (United States)

    Bulgarelli, Daniela; Testa, Silvia; Molina, Paola

    2015-06-01

    This study examined the factorial structure of the Theory of Mind (ToM) Storybooks, a comprehensive 93-item instrument tapping the five components in Wellman's model of ToM (emotion recognition, understanding of desire and beliefs, ability to distinguish between physical and mental entities, and awareness of the link between perception and knowledge). A sample of 681 three- to eight-year-old Italian children was divided into three age groups to assess whether factorial structure varied across different age ranges. Partial credit model analysis was applied to the data, leading to the empirical identification of 23 composite variables aggregating the ToM Storybooks items. Confirmatory factor analysis was then conducted on the composite variables, providing support for the theoretical model. There were partial differences in the specific composite variables making up the dimensions for each of the three age groups. A single test evaluating distinct dimensions of ToM is a valuable resource for clinical practice which may be used to define differential profiles for specific populations. © 2014 The British Psychological Society.

  15. Language and ToM Development in Autism versus Asperger Syndrome: Contrasting Influences of Syntactic versus Lexical/Semantic Maturity

    Science.gov (United States)

    Paynter, Jessica; Peterson, Candida

    2010-01-01

    Theory of mind (ToM) development by a sample of 63 children aged 5-12 years (24 with Asperger syndrome, 19 with high-functioning autism, and 20 age-matched typical developers) was assessed with a five-task false-belief battery in relation to both lexical (vocabulary) and syntactic (grammar) language skills. Contrary to some previous research, no…

  16. From the External to the Internal: Behavior Clarifications Facilitate Theory of Mind (ToM) Development in Chinese Children

    Science.gov (United States)

    Liu, Yanchun; Wang, Yijie; Luo, Rufan; Su, Yanjie

    2016-01-01

    The present study investigated how Chinese children develop theory of mind (ToM) in a language environment with limited mental state talk that is rich in behavior discourse. In Study 1, 60 mothers shared a wordless storybook with their 3-4-year-olds. The children completed two false-belief tasks and the Peabody Picture Vocabulary Test-Revised at…

  17. Limited Evaluation of Image Quality Produced by a Portable Head CT Scanner (CereTom) in a Neurosurgery Centre

    Science.gov (United States)

    Abdullah, Ariz Chong; Adnan, Johari Siregar; Rahman, Noor Azman A.; Palur, Ravikant

    2017-01-01

    Introduction Computed tomography (CT) is the preferred diagnostic toolkit for head and brain imaging of head injury. A recent development is the invention of a portable CT scanner that can be beneficial from a clinical point of view. Aim To compare the quality of CT brain images produced by a fixed CT scanner and a portable CT scanner (CereTom). Methods This work was a single-centre retrospective study of CT brain images from 112 neurosurgical patients. Hounsfield units (HUs) of the images from CereTom were measured for air, water and bone. Three assessors independently evaluated the images from the fixed CT scanner and CereTom. Streak artefacts, visualisation of lesions and grey–white matter differentiation were evaluated at three different levels (centrum semiovale, basal ganglia and middle cerebellar peduncles). Each evaluation was scored 1 (poor), 2 (average) or 3 (good) and summed up to form an ordinal reading of 3 to 9. Results HUs for air, water and bone from CereTom were within the recommended value by the American College of Radiology (ACR). Streak artefact evaluation scores for the fixed CT scanner was 8.54 versus 7.46 (Z = −5.67) for CereTom at the centrum semiovale, 8.38 (SD = 1.12) versus 7.32 (SD = 1.63) at the basal ganglia and 8.21 (SD = 1.30) versus 6.97 (SD = 2.77) at the middle cerebellar peduncles. Grey–white matter differentiation showed scores of 8.27 (SD = 1.04) versus 7.21 (SD = 1.41) at the centrum semiovale, 8.26 (SD = 1.07) versus 7.00 (SD = 1.47) at the basal ganglia and 8.38 (SD = 1.11) versus 6.74 (SD = 1.55) at the middle cerebellar peduncles. Visualisation of lesions showed scores of 8.86 versus 8.21 (Z = −4.24) at the centrum semiovale, 8.93 versus 8.18 (Z = −5.32) at the basal ganglia and 8.79 versus 8.06 (Z = −4.93) at the middle cerebellar peduncles. All results were significant with P-value < 0.01. Conclusions Results of the study showed a significant difference in image quality produced by the fixed CT scanner and

  18. Transformation of PRT6 RNAi construct into tomato (Solanum lycopersicum) cv. Micro-Tom

    Science.gov (United States)

    Suka, Intan Elya; Chew, Bee Lynn; Goh, Hoe-Han; Isa, Nurulhikma Md

    2018-04-01

    PROTEOLYSIS 6 plays major role in the N-end rule pathway as N-recognin which functions as E3 ligase enzyme. It mediates ubiquitin processes that lead to degradation of unstable substrate protein. The aim of the current study is to transform the PRT6 gene into tomato (Solanum lycopersicum) from the cultivar Micro-Tom and to investigate its function in regulating ripening in tomato fruits. The PRT6_RNAi construct was successfully transformed into Agrobacterium C58 via heat shock method and transformed into seven days old cotyledon explants. Factors affecting transformation efficiency such as co-cultivation time and type of plant growth regulator combination were evaluated. Results from this study found that pre-cultured cotyledons from seven days old seedlings incubated for 2 days in co-cultivation medium increased shoot regeneration. Plant growth hormones zeatin combine with auxin produced a higher number of callus formation but lower shoot proliferation and transformation frequency compared to treatments of single plant hormone in the selection medium. Polymerase chain reaction (PCR) was performed on the regenerated shoots to confirm the integration of PRT6 fragment into the genome of transgenic plants. Based on PCR analysis, all putative shoots were positive transformants.

  19. Test-retest reliability and validity of the Sniffin' TOM odor memory test.

    Science.gov (United States)

    Croy, Ilona; Zehner, Cora; Larsson, Maria; Zucco, Gesualdo M; Hummel, Thomas

    2015-03-01

    Few attempts have been made to develop an olfactory test that captures episodic retention of olfactory information. Assessment of episodic odor memory is of particular interest in aging and in the cognitively impaired as both episodic memory deficits and olfactory loss have been targeted as reliable hallmarks of cognitive decline and impending dementia. Here, 96 healthy participants (18-92 years) and an additional 19 older people with mild cognitive impairment were tested (73-82 years). Participants were presented with 8 common odors with intentional encoding instructions that were followed by a yes-no recognition test. After recognition completion, participants were asked to identify all odors by means of free or cued identification. A retest of the odor memory test (Sniffin' TOM = test of odor memory) took place 17 days later. The results revealed satisfactory test-retest reliability (0.70) of odor recognition memory. Both recognition and identification performance were negatively affected by age and more pronounced among the cognitively impaired. In conclusion, the present work presents a reliable, valid, and simple test of episodic odor recognition memory that may be used in clinical groups where both episodic memory deficits and olfactory loss are prevalent preclinically such as Alzheimer's disease. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. Dementia and well-being: A conceptual framework based on Tom Kitwood's model of needs.

    Science.gov (United States)

    Kaufmann, Elke G; Engel, Sabine A

    2016-07-01

    The topic of well-being is becoming increasingly significant as a key outcome measure in dementia care. Previous work on personhood of individuals with dementia suggests that their subjective well-being can be described in terms of comfort, inclusion, identity, occupation and attachment The study aimed to examine Tom Kitwood's model of psychological needs and well-being in dementia based on the self-report of individuals with moderate or severe dementia and to differentiate and elaborate this model in the light of the empirical qualitative data. Nineteen inhabitants of a special long-term care unit were interviewed using a semi-structured interview. Data were analysed using content analysis. Thirty components within Kitwood's model have been identified. A conceptual framework of subjective well-being in dementia was developed based on a theoretical background. The study was able to find indications that Kitwood's model has empirical relevance. Nevertheless, it requires to be extended by the domain agency. Furthermore, the study suggests that individuals with dementia are important informants of their subjective well-being. © The Author(s) 2014.

  1. Polo gastronómico Tomás Jofré

    Directory of Open Access Journals (Sweden)

    Regina G. Schlüter

    2008-01-01

    Full Text Available El turismo gastronómico está adquiriendo cada vez mayor importancia en el mundo, independientemente de si se trata de un país desarrollado o no. En Argentina este tipo de turismo cuenta con una larga tradición, en particular referida al enoturismo que se refleja en la Fiesta Nacional de la Vendimia que se lleva a cabo desde 1936 en la provincia de Mendoza. Hacia fines del siglo XX un plan nacional de turismo hace referencias explícitas a las rutas alimentarias y a partir de allí, desde el sector privado, surgen iniciativas para desarrollar destinos en función de su gastronomía. Una de estas iniciativas se relaciona con la transformación de un pequeño pueblo en un polo gastronómico de gran atracción. En este artículo se presentan los resultados de un estudio que se hizo en el mismo para determinar el perfil de los visitantes y las motivaciones que tienen las personas para desplazarse hacia Tomás Jofré los días domingos.

  2. Averroes y Tomás de Aquino sobre el concepto de ciencia natural

    Directory of Open Access Journals (Sweden)

    Lértora Mendoza, Celina Ana

    2007-01-01

    Full Text Available Al comienzo del libro I de la Physica, Aristóteles plantea la pregunta por la materia y el sujeto de la ciencia natural. Esta cuestión se refiere al concepto de la ciencia cuya indagación inicia. La ciencia natural (philosophia naturalis ha sido en lo sucesivo objeto de indagaciones específicas, sobre todo en función del comentario al original aristotélico. Averroes1 dedica al tema un conciso y a la vez comprehensivo Proemio. Tomás de Aquino,2 en cambio, y al contrario de otros casos, omite un proemio metodológico, si bien el tema en sí se desarrolla al hilo del comentario del texto del Libro I. El objetivo de este trabajo es analizar las aproximaciones y las diferencias entre la lección I del Comentario al Libro I del Aquinate (donde trata el método de la philosophia naturalis y la exégesis de Averroes en su Proemio y la Summa Prima, a fin de establecer las relaciones entre ambos

  3. Intercomparison of preliminary MFR, SBUV, TOMS, and TOVS total ozone data

    International Nuclear Information System (INIS)

    Luther, F.M.

    1992-01-01

    The High Altitude Pollution Program of the Federal Aviation Administration is sponsoring a comparative study of total ozone data derived from various satellite instruments. The instruments included in the study are the Defense Meteorological Satellite Program's Multichannel Filter Radiometer (MFR), the NASA Solar Backscatter Ultraviolet Ozone Experiment (SBUV), the NASA Total Ozone Mapping Spectrometer (TOMS), and the NOAA Tiros Operational Vertical Sounder (TOVS). The two periods chosen for data intercomparison are January 1 - February 15, 1979 and June 1-30, 1979. These two data periods cover summer and winter regimes in both hemispheres. The January 1 - February 15, 1979 period includes a significant stratospheric warming event that began about January 15. Each of the satellite instruments has its own strengths and weaknesses. No instrument is universally better than or worse than any other in terms of accuracy, although they appear to have definite biases in certain geographical areas. The differences between the satellite systems is greatest at high latitudes where cloudiness and ozone variabilities are greatest. The Dobson data show a bias and differing degrees of ozone variability between nearby Dobson stations, which indicates there may be problems with using the Dobson data as a standard for comparison. The data used in this comparative study are preliminary in nature

  4. Some assembly required: Contributions of Tom Stevens' lab to the V-ATPase field.

    Science.gov (United States)

    Graham, Laurie A; Finnigan, Gregory C; Kane, Patricia M

    2018-06-01

    Tom Stevens' lab has explored the subunit composition and assembly of the yeast V-ATPase for more than 30 years. Early studies helped establish yeast as the predominant model system for study of V-ATPase proton pumps and led to the discovery of protein splicing of the V-ATPase catalytic subunit. The Vma - phenotype, characteristic of loss-of-V-ATPase activity in yeast was key in determining the enzyme's subunit composition via yeast genetics. V-ATPase subunit composition proved to be highly conserved among eukaryotes. Genetic screens for new vma mutants led to identification of a set of dedicated V-ATPase assembly factors and helped unravel the complex pathways for V-ATPase assembly. In later years, exploration of the evolutionary history of several V-ATPase subunits provided new information about the enzyme's structure and function. This review highlights V-ATPase work in the Stevens' lab between 1987 and 2017. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. India and England in the Mirror. A Post-imperial Portrait of Tom Stoppard

    Directory of Open Access Journals (Sweden)

    Lucia Esposito

    2011-11-01

    Full Text Available The paper is focused on a sophisticated radio play by Tom Stoppard, In the Native State (1991, in which the dramatist approaches the problems linked to the ethics of the British Empire in dealing with Indian culture in both the colonial and post-colonial periods. To do this, the play confronts and complexly interlaces two different sets, India in the Thirties and London in 1990, as if they were two worlds reflecting themselves in a time mirror. The issues dealt with, such as the centuries-old westernization of the Indian minds and culture on one side, and the Indianization of British language and customs on the other, are subtlety treated in art terms, as the reciprocal relationship between the two worlds conflates in the hybrid style of the portraits executed by the hand of an Indian painter who, notwithstanding, or thanks to, his mimic identity (in Homi Bhabha’s terms, becomes the mouthpiece of a fundamental ‘change of perspective’, from the Eurocentric representation of the Orient (in Edward Said’s terms to the re-appropriation of a different point of view translating the achievement of the Nationalist movement that led India to independence in the Forties.

  6. Tom McCarthy, Karl Marx, and the Money on the Books

    Directory of Open Access Journals (Sweden)

    Nicholas Huber

    2017-11-01

    Full Text Available By way of contrast to recent work on the problematic of representation of capital and its prioritized aesthetic mode, visuality, this article addresses the problematic of mediation in financialized capitalism through an attention to the relationship between writing and contemporary money forms. To elaborate this problematic, mediation is deployed methodologically as well: selections from two bodies of work concerned with capitalist monetary phenomena—those of Karl Marx and the novelist Tom McCarthy—are analyzed in parallel. McCarthy’s 'oeuvre' is presented as preoccupied with monetary-inscriptive techniques and pockmarked by Marxian concepts and concerns. It is argued that 'Remainder', specifically, can be read as theorizing the relationship between money and writing under early 21st-century regimes of finance capital through its elaboration of retail loyalty accounts and the multivalent concept of ‘remainder’ or ‘surplus’. The article reads this theorization against neglected sections of Marx’s second volume of 'Capital' in which money is enigmatically treated from the perspective of bookkeeping.

  7. La libertad humana como valor primordial en Tomás de Aquino

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    Dietrich Lorenz

    2004-01-01

    Full Text Available Me he propuesto en este artículo acercarme a la relación que existe en Tomás de Aquino entre el concepto de persona, libertad y felicidad, teniendo presente que, en este autor, aquel que es llamado a pensar su felicidad y sus deseos, no es el hombre en abstracto, como se tiende a pensar, sino este hombre (hoc aliquid de frente y en relación a la naturaleza de la cual forma parte, frente a otros hombres con quienes convive, y frente al fin último que lo ayuda a orientarseIn this article, the author attempts to disclose the relationship between the concepts of person, liberty and happiness in Thomas Aquinas thought. To do so, the author emphasizes the point that in Aquinas' work Man is not an abstraction, as it is usually thought, but a real Man who is called to think of his happiness and desires. This man (hoc aliquid is the one who faces and relates to nature, of which he is part of, the one who faces other men he lives with, and the one who faces the ultimate end, which helps him find his orientation

  8. Analysis of cohesive devices in a short text: 'Whiskey. No water. No ice.' by Tom Hart

    Directory of Open Access Journals (Sweden)

    Janković Anita V.

    2017-01-01

    Full Text Available The aim of this paper was two-fold. Primarily, based on literature review, it presented various takes on what constitutes a text and what makes it cohesive. Secondly, it reported the results of the cohesion analysis performed on a short drama by Tom Hart. This drama was written as a submission for the London Royal Court Theatre competition '100 Word Play'. The author used the model of analysis of a dramatic dialogue proposed by Halliday and Hassan. The dramatic dialogue here is characterized as a speaking text, for the stage; therefore, the stage directions were excluded from the analysis as para-linguistic phenomena. The results of the analysis revealed immediate ellipsis of anaphoric direction as the most common cohesive device in 47 percent of the text. Second in frequency are referencing mechanisms, and finally lexical devices and connectors. Furthermore, the analysis exposed the use of reiteration, both lexical and structural, which is not predicted by the model. However, these instances were explained by Hoey's model of lexical repetition. The thematic progression in the text is linear which is characteristic of dialogues. The analysis noted no usage of substitution nor parallelism, which is in itself indicative of the set hypothesis because parallelisms are characteristic of poetry and political discourse.

  9. Língua Gestual de São Tomé e Príncipe : retrato dos primeiros gestos

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    Ana Mineiro

    2016-09-01

    Full Text Available This paper aims to portray the genesis of São Tomé and Príncipe Sign Language. At the request of the Government of São Tomé and Principe (Ministry of Education, Culture and Science, Cell Special Education, the Portuguese Catholic University together with the Marquês of Valle Flôr Institute and Hospital CUF Infante Santo collaborated on a common project: to implement a Sign Language for the deaf Santomean. This project, funded by the Calouste Gulbenkian Foundation, was given the name of Without Barriers. The paper is structured in two parts: the first part, which describes, in summary, the main lines of action of the project, the participants enrolled in the project and the methodology used and the second part that analyzes the emergence of the first signs, using sometimes, comparison with other emerging languages.

  10. Gastronomía y turismo en Argentina. Polo gastronómico Tomás Jofré

    Directory of Open Access Journals (Sweden)

    Schlüter, Regina G.

    2008-04-01

    Full Text Available Culinary Tourism in Argentina. The Case of Tomás Jofré. The importance of culinary tourism is growing steadily both in developing and industrialized societies. Argentina has a long tradition regarding this kind of tourism, mainly wine tourism, reflected in the National Wine Festival held since 1936 en the province of Mendoza. By the end of the 20th century culinary tourism was brought into the national tourism plan and it was the start for the private sector to develop own initiatives in order to develop small towns into culinary attractions for visitors. This article presents the results of a study undertaken in order to get acquainted with the visitor profile and motivations for visitors to Tomás Jofré during Sun-days.

  11. ‘My country’s heart is in the market place’: Tom Stannage interviewed by Peter Read

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    Tiffany Shellam

    2013-12-01

    Full Text Available Tom Stannage was one among many historians in the 1970s uncovering histories of Australia which were to challenge national narratives and community memories. In 1971, Tom returned to Western Australia after writing his PhD in Cambridge with the passion to write urban history and an understanding that in order to do so, he needed an emotional engagement with place. What he had yet to realize was the power of community memories in Western Australia to shape and preserve ideas about their place. As part of his research on the history of Perth, Tom saw how the written histories of Western Australia had been shaped by community mythologies – in particular that of the rural pioneer. He identified the consensus or ‘gentry tradition’ in Western Australian writing. In teasing out histories of conflict, he showed how the gentry tradition of rural pioneer histories silenced those of race and gender relations, convictism and poverty which were found in both rural and urban areas. His versions of history began to unsettle parts of the Perth community who found the ‘pioneer myth’ framed their consensus world-view and whose families were themselves the living links to these ‘pioneers’.

  12. Race Matters… Still. Rezension zu Tom Angotti und Sylvia Morse (Hg. (2016: Zoned Out! Race, Displacement, and City Planning in New York City. New York City: Terreform.

    Directory of Open Access Journals (Sweden)

    Yuca Meubrink

    2017-06-01

    Full Text Available In ihrem Sammelband Zoned Out! identifizieren Tom Angotti und Sylvia Morse zoning als eines der Planungsinstrumente, welches die historischen Muster ethnischer Diskriminierung und Segregation in New York bis heute immer wieder reproduziert hat. [...

  13. TOMS/Nimbus-7 Total Ozone Aerosol Index UV-Reflectivity UV-B Erythemal Irradiances Daily L3 Global 1x1.25 deg V008

    Data.gov (United States)

    National Aeronautics and Space Administration — The Total Ozone Mapping Spectrometer (TOMS) version 8 Daily Gridded Data consist of daily, global coverage of total column ozone, aerosol index, Lambertian effective...

  14. THIR/Nimbus-7 Level 1 Cloud Data for SBUV/TOMS V001 (THIRN7L1BCLT) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — THIRN7L1BCLT is the Nimbus-7 Temperature-Humidity Infrared Radiometer (THIR) Level 1 Cloud Data for SBUV/TOMS (BCLT) product and contains total cloud amounts;...

  15. OMI/Aura TOMS-Like Ozone and Radiative Cloud Fraction Daily L3 Global 0.25x0.25 deg V003

    Data.gov (United States)

    National Aeronautics and Space Administration — The Version-003 of Level-3 Aura/OMI daily global TOMS-Like Total Column Ozone gridded product (OMTO3e) is generated by the NASA OMI science team by picking the best...

  16. Teenage pregnancy - a study in São Tomé and Príncipe.

    Science.gov (United States)

    Carvalho, Fábia; Medeiros, Inês de; Faria, Catarina; Cotu, Djamilla; Will, Endza Paula; Neves, Edgar; Pontes, Teresa

    2017-08-22

    Introduction The increasing number of pregnant teenagers in São Tomé and Príncipe (STP) represents a serious public health issue. The aim of this study was to characterize the population of pregnant adolescents followed in a health facility dedicated to maternal health in STP. Methods A cross-sectional survey was conducted among pregnant teenagers that attended the Mother and Child Protection Center during the first quarter of 2017. The survey contained questions on sociodemographic characteristics, sexual and risk behaviors, family, partners and health support. Results The mean age of the 51 pregnant teenagers included was 16.37 ± 0.8 years. Eight girls reported that they had planned to fall pregnant. Teenagers whose pregnancy was unplanned usually present with a previous family history of adolescent pregnancy. About 59% of girls engaged in sexual activity before 16 years of age with a mean number of sexual partners of 1.84 ± 0.88. In this study, 51% of the girls do not use any contraceptive method, usually because their partner refuses to do so. The preferred contraceptive method are condoms. Information on contraception is given mainly at school. Pregnant girls' first medical consultation was at a mean gestational age of 6 weeks. Abortion was considered by 51% of girls after pregnancy was confirmed. Conclusion Teenage pregnancy imposes health problems for the mother and child and contributes to educational and socioeconomic disadvantages. The collaboration of healthcare providers, teachers and parents is needed to enhance sexual health education. This is the first study in STP on teenage pregnancy; although the sample is small, the authors believe that the results are representative of the general population.

  17. The Former Miss Barstow with every Tom, Dick and Harry in a doll's house

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    Richard Newton

    2015-02-01

    Full Text Available Julie Holledge, panel chairperson and member of the International Ibsen Committee, invited myself along with 3 others to participate in the Inaugural Artists’ Keynote Panel: Applied Ibsen on Four Continents: The Artists’ Intentions. My presentation focused on “The Former Miss Barstow with every Tom, Dick and Harry in a doll’s house.” This was an adaptation of Ibsen’s “A Doll’s House” produced and staged in Los Angeles, California, 1987.  For the XIIIth International Ibsen Conference at the University of Tromsø, Norway, I projected images; a few found on the internet, and many from the production itself, as well as a video clip shown streaming live from YouTube. The article describes the social context of the 80s, analyzes the reinterpretation of Ibsen’s characters, and sets out to explain the symbology of the sets and costumes. I also touch on the differences between this production and Ibsen’s original in four important aspects. These would be the macaroons, the Tarantella, the silk stockings and the end of the play. Finally, I explain my decision to upload this version of “A Doll’s House,’ scene by scene, to my page on YouTube. Having shown films and videos for many years at festivals around the globe, I was looking for a way to step outside that box and reach an international audience just beyond my keyboard. In all of these ways, the goal has been to illuminate the ways in which an artist takes Ibsen’s text and applies it to the specific social context of their time and culture.

  18. Ecologization of water-land property matters on the territory of the Tom lower course

    Science.gov (United States)

    Popov, V. K.; Kozina, M. V.; Levak, Yu Yu; Shvagrukova, E. V.

    2016-03-01

    In the present paper the water-land property complex is considered as a strategic resource of the city development. The formulated question is expounded through the example of water-land property complex usage on the territory of the Tom lower course for land-use planning and developing the systems of water recourses management and land tenure. Consequences of liquid radioactive waste (LRW) landfilling are investigated in terms of arable farming. Also, forming a water budget of the soils spread on the area of the Tomsk underground water supply cone of depression and its role in the development of agricultural industry are studied. The main aspect of the analysis is the incorporation of social, economic, and ecological requirements for the system of life-supporting branches of municipal economy and social services. As far as the system of land tax payments plays an important role in land property complex management, the common issues and tendencies are specified in the paper. These problems are concerned with the inadequate incorporation of an ecological constituent in the methods of cadastral valuation of lands, as well as the situation of the narrow area of its results usage in the Russian Federation. Natural factors (hydrological, territorial, geological (geomorphologic) territory conditions) are combined by the authors into a special group. These factors should be reflected in the results of cadastral valuation. Also, in order to protect the interests of water consumers, it is offered to establish the Water Consumers Association based on the international experience of such countries as Spain and Uzbekistan.

  19. Metabolite profile of the tomato dwarf cultivar Micro-Tom and comparative response to saline and nutritional stresses with regard to a commercial cultivar.

    Science.gov (United States)

    Flores, Pilar; Hernández, Virginia; Hellín, Pilar; Fenoll, Jose; Cava, Juana; Mestre, Teresa; Martínez, Vicente

    2016-03-30

    The dwarf tomato variety Micro-Tom has been used as a plant model for studies of plant development. However, its response to environmental and agricultural factors has not been well studied. This work studies the phytochemical content of Micro-Tom tomato and its comparative response to saline and nutritional (N, K and Ca) stresses with regard to a commercial variety. The chromatographic profiles of Micro-Tom were similar to those of the commercial variety and the only differences appear to be the concentration of the components. In Micro-Tom, the concentrations of sugars and organic acids increased by salinity in a lesser extent than in Optima. Moreover, contrary to that observed in the commercial variety, phenolic compounds and vitamin C did not increase by salinity in the dwarf variety. However, both varieties increased similarly the concentrations of carotenoids under saline conditions. Finally, fruit yield and most primary and secondary metabolite concentrations in Micro-Tom were not affected by N, K or Ca limitation. The mutations leading to the dwarf phenotype did not greatly alter the metabolite profiles but studies using Micro-Tom as a plant model should consider the lower capacity for sugars and organic acids under saline conditions and the greater tolerance to nutrient limitation of the dwarf variety. © 2015 Society of Chemical Industry.

  20. Physico-chemical and sensory characterization of fruit jams of S. Tomé and Príncipe

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    Elsa Ramalhosa

    2017-05-01

    Full Text Available Introduction: São Tomé and Príncipe has a wide variety of fruit trees, being most of the fruits consumed in fresh. In certain periods of the year, fruits are available at significant amounts; however, it is not common to use the surplus of those fruits. Thus, this excess may be used in the preparation of other fruit based products (ex. jams, in order to increase product diversity and allow the annual consumption of these seasonal fruits. Objetives: Valorise fruits’ production in S. Tomé and Príncipe. Methods: Preparation of jams of banana, ambarella, guava (dark and light and papaya, with two levels of sugar, and perform their physico-chemical characterization (color, pH, moisture and acidity. Furthermore, sensory analysis was also done, through preference and acceptability tests. Results: The jams prepared had different colours, acidity values, and moisture and ash contents, demonstrating the possibility of producing different products by changing the formulation. Regarding jams preference, 60% of the consumers preferred the less sweet in the case of banana and guava (light, whereas, over 67% of the panellists preferred the sweetest ambarella jam. Concerning dark guava and papaya, the percentages were similar for both sugar contents. For all attributes analysed (appearance, colour, taste, acidity, sweetness and global evaluation, most of the panellists liked slightly all jams. Conclusion: Jams production in S. Tomé and Príncipe may be a promising activity.

  1. The TOMS V9 Algorithm for OMPS Nadir Mapper Total Ozone: An Enhanced Design That Ensures Data Continuity

    Science.gov (United States)

    Haffner, D. P.; McPeters, R. D.; Bhartia, P. K.; Labow, G. J.

    2015-12-01

    The TOMS V9 total ozone algorithm will be applied to the OMPS Nadir Mapper instrument to supersede the exisiting V8.6 data product in operational processing and re-processing for public release. Becuase the quality of the V8.6 data is already quite high, enchancements in V9 are mainly with information provided by the retrieval and simplifcations to the algorithm. The design of the V9 algorithm has been influenced by improvements both in our knowledge of atmospheric effects, such as those of clouds made possible by studies with OMI, and also limitations in the V8 algorithms applied to both OMI and OMPS. But the namesake instruments of the TOMS algorithm are substantially more limited in their spectral and noise characterisitics, and a requirement of our algorithm is to also apply the algorithm to these discrete band spectrometers which date back to 1978. To achieve continuity for all these instruments, the TOMS V9 algorithm continues to use radiances in discrete bands, but now uses Rodgers optimal estimation to retrieve a coarse profile and provide uncertainties for each retrieval. The algorithm remains capable of achieving high accuracy results with a small number of discrete wavelengths, and in extreme cases, such as unusual profile shapes and high solar zenith angles, the quality of the retrievals is improved. Despite the intended design to use limited wavlenegths, the algorithm can also utilitze additional wavelengths from hyperspectral sensors like OMPS to augment the retreival's error detection and information content; for example SO2 detection and correction of Ring effect on atmospheric radiances. We discuss these and other aspects of the V9 algorithm as it will be applied to OMPS, and will mention potential improvements which aim to take advantage of a synergy with OMPS Limb Profiler and Nadir Mapper to further improve the quality of total ozone from the OMPS instrument.

  2. Strong enhancement of Penning ionization for asymmetric atom pairs in cold Rydberg gases: the Tom and Jerry effect

    KAUST Repository

    Efimov, D K

    2016-05-18

    We consider Penning ionization of Rydberg atom pairs as an Auger-type process induced by the dipole-dipole interaction and employ semiclassical formulae for dipole transitions to calculate the autoionization width as a function of the principal quantum numbers, n d, n i, of both atoms. While for symmetric atom pairs with the well-known increase of the autoionization width with increasing n 0 is obtained, the result for asymmetric pairs is counterintuitive - for a fixed n i of the ionizing atom of the pair, the autoionization width strongly increases with decreasing n d of the de-excited atom. For H Rydberg atoms this increase reaches two orders of magnitude at the maximum of the n d dependence, and the same type of counterintuitive behavior is exhibited also by Na, Rb and Cs atoms. This is a purely quantum-mechanical effect, which points towards existence of optimal (we call them \\'Tom\\' and \\'Jerry\\' for \\'big\\' and \\'small\\') pairs of Rydberg atoms with respect to autoionization efficiency. Building on the model of population redistribution in cold Rydberg gases proposed in [1], we demonstrate that population evolution following the initial laser excitation of Rydberg atoms in state n 0 would eventually lead to the formation of such Tom-Jerry pairs with which feature autoionization widths that are enhanced by several orders of magnitude compared to that of two atoms in the initial laser-excited state n 0. We also show that in the high-density regime of cold Rydberg gas experiments the ionization rate of Tom-Jerry pairs can be substantially larger than the blackbody radiation-induced photoionization rate. © 2016 IOP Publishing Ltd.

  3. Semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant.

    Science.gov (United States)

    Romagnoli, Stefano; Baldan, Anna; Righetti, Camilla; Milani, Chiara; Mollo, Antonio; Stelletta, Calogero

    2017-02-01

    Objectives Gonadotropin-releasing hormone (GnRH) agonists like deslorelin are being increasingly used in tom cats for their efficacy in controlling reproductive behaviour and fertility. Deslorelin implants have been widely available in Europe since 2008. Little, if anything, is known about the interval between treatment and onset of sterility, as well as semen quality, after treatment in tom cats. The purpose of this study was to investigate semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant. Methods Fifteen healthy adult tom cats were treated with a 9.4 mg deslorelin implant (Suprelorin 12). For each cat, semen collection and a GnRH stimulation test (intramuscular administration of 50 μg gonadorelin [Fertagyl], followed by blood sampling 1 h later, to assay serum testosterone) were performed on the first consultation and then repeated every 15 days until complete sterility was achieved. Semen collection was performed by introducing a 14 cm, open-end feline catheter (Argyle) 9 cm into the distal urethra 10 mins after sedation by intramuscular injection of 100 μg/kg medetomidine (Domitor). Results Semen collection was not successful in all cats at each attempt. In the first month after treatment, the semen of only four cats could be evaluated, while the semen of eight cats could be evaluated during the second and third months of the study. Semen quality (ejaculate volume, progressive motility and morphological abnormalities) improved slightly during the first 19-25 days in 2/4 cats, and in 1/4 cats motility was still very high (80%) 25 days post-treatment (PT), but we have no data regarding fertility prior to treatment in this cat. The last cat never produced spermatozoa. Subsequently, semen quality gradually worsened in all cats from 30 days onwards. At 70 days PT, one cat was still potentially fertile. After 72 days all cats were sterile. Conclusions and relevance Semen quality increased slightly in treated cats during

  4. Recuperación del borde costero, la transformación de una ciudad. Tomé

    Directory of Open Access Journals (Sweden)

    Marcela Moraga Mansoulet

    2007-11-01

    Desde la visión de una ciudad industrial y textil; declarada en 1958, Puerto Mayor, para el comercio e intercambio con el extranjero, a la decadencia de este mismo puerto, producto de la llegada de ferrocarriles, y el cambio paulatino de rol de la ciudad, es que actualmente Tomé se puede definir como una ciudad en proceso de transformación y transición, dejando atrás su histórico pasado, para transformarse en una ciudad enfocada principalmente al desarrollo de turismo, como objetivo principal, de acuerdo a las necesidades de los tiempos que hoy transcurren.

  5. Annotated catalogue of the flowering plants of São Tomé and Príncipe

    Directory of Open Access Journals (Sweden)

    E. Figueiredo

    2011-12-01

    Full Text Available A catalogue of the flowering plants of the islands of São Tomé and Príncipe (Gulf of Guinea is presented. Flowering plant diversity figures are updated to: 135 families (20 introduced, 624 genera (172 introduced, 1 104 species (301 introduced plus 15 additional infraspecific taxa. At present 119 taxa (107 species and 12 infraspecific taxa are known to be endemic to the two islands. The catalogue includes accepted names, synonyms used in recent literature, common names, voucher specimens and information on habit and habitat and on plant uses, particularly medicinally.

  6. Cruzando fronteras nacionales: hacia una cartografía del ensayismo de Tomás Segovia

    NARCIS (Netherlands)

    Houvenaghel, E.M.H.

    2014-01-01

    El poeta y ensayista hispanomexicano Tomás Segovia (Valencia 1927 – México 2011) vivió entre diferentes mundos: es de origen español y se exilió primero a Francia y después a a México, país en el que residió durante más de cuatro décadas, antes de regresar a Francia y España en 1985. Con el fin de

  7. Estimations of the Global Distribution and Time Series of UV Noontime Irradiance (305, 310, 324, 380 nm, and Erythemal) from TOMS and SeaWiFS Data

    Science.gov (United States)

    Herman, J.

    2004-01-01

    The amount of UV irradiance reaching the Earth's surface is estimated from the measured cloud reflectivity, ozone, aerosol amounts, and surface reflectivity time series from 1980 to 1992 and 1997 to 2000 to estimate changes that have occurred over a 21-year period. Recent analysis of the TOMS data shows that there has been an apparent increase in reflectivity (decrease in W) in the Southern Hemisphere that is related to a calibration error in EP-TOMS. Data from the well-calibrated SeaWiFS satellite instrument have been used to correct the EP-TOMS reflectivity and UV time series. After correction, some of the local trend features seen in the N7 time series (1980 to 1992) have been continued in the combined time series, but the overall zonal average and global trends have changed. In addition to correcting the EP-TOMS radiance calibration, the use of SeaWiFS cloud data permits estimation of UV irradiance at higher spatial resolution (1 to 4 km) than is available from TOMS (100 km) under the assumption that ozone is slowly varying over a scale of 100 km. The key results include a continuing decrease in cloud cover over Europe and North America with a corresponding increase in UV and a decrease in UV irradiance near Antarctica.

  8. TOM1L Is Involved in a Novel Signaling Pathway Important for the IL-2 Production in Jurkat T Cells Stimulated by CD3/CD28 CoLigation

    Directory of Open Access Journals (Sweden)

    Ahmed Elmarghani

    2009-01-01

    Full Text Available TOM1L (target of Myb-1 Like was identified as a binding partner for the full length and catalytically-active Lck in a yeast 2-hybrid screening assay. Here we show that in Jurkat T cells stimulated by CD3/CD28 coligation where the expression of TOM1L is reduced by lenti virus mediated-siRNA results in a dramatically lower IL-2 production. The production of IL-2 in siRNA treated cells stimulated with PMA/ionomycin was not affected indicating an involvement of TOM1L in a pathway proximal of TCR and CD28. The coexpression of Fyn with TOM1L increased the level of the phosphorylated form of Fyn indicating that TOM1L has the ability to activate Fyn. The ability of TOM1L to activate Fyn was further shown in a kinase assay using angiotensin II as a substrate. By confocal microscopy, we show that the expression of TOM1L in non-treated HeLa and SK-N-SH cells colocalizes with the mitochondrial membrane but not with lysosomal compartments or the trans-Golgi network. Furthermore, we show that the over-expression of TOM1L in Jurkat cells causes an increase of the STAT3 expression . Based on our results, we here propose that TOM1L is involved in a novel signaling pathway that is important for the IL-2 production in T cells.

  9. Finishing broiler toms using an estradiol 17 beta implant together with a high energy-low protein final feed.

    Science.gov (United States)

    Moran, E T; Etches, R J

    1983-06-01

    Wrolstad Small White toms were implanted with 10 mg of estradiol 17 beta monopalmitate (EMP) at 8 weeks of age. Common corn-soybean meal feeds were given through to 12 weeks, then one-half the birds from control and EMP groups received either an adequate (16% protein, 3166 kcal ME/kg) or high energy-low protein (HE-LP, 12%, 3373 kcal) feed to 14 weeks. No differences in weight gain and feed conversion occurred between EMP and control treatments at 12 weeks but at 14 weeks when the HE-LP diet had been fed the implanted birds performed better than controls. The HE-LP feed led to body weights and feed efficiencies below that of toms given adequate diet. In all cases, EMP elicited male secondary sex characteristics rather than feminization. Processing losses were increased with EMP and when the HE-LP feed had been given. Both treatments also improved finish assessment and were additive to the extent that a substantial increase in grade occurred. Effects on carcass composition, yield of commercial cuts, and cooking loss were small. Implantation, reduced meat yield percentage of breast and thigh. The increase in grade advantage from combining EMP with a feed that forced fat deposition more than compensated for the adverse effects.

  10. Mapping of Micro-Tom BAC-End Sequences to the Reference Tomato Genome Reveals Possible Genome Rearrangements and Polymorphisms

    Science.gov (United States)

    Asamizu, Erika; Shirasawa, Kenta; Hirakawa, Hideki; Sato, Shusei; Tabata, Satoshi; Yano, Kentaro; Ariizumi, Tohru; Shibata, Daisuke; Ezura, Hiroshi

    2012-01-01

    A total of 93,682 BAC-end sequences (BESs) were generated from a dwarf model tomato, cv. Micro-Tom. After removing repetitive sequences, the BESs were similarity searched against the reference tomato genome of a standard cultivar, “Heinz 1706.” By referring to the “Heinz 1706” physical map and by eliminating redundant or nonsignificant hits, 28,804 “unique pair ends” and 8,263 “unique ends” were selected to construct hypothetical BAC contigs. The total physical length of the BAC contigs was 495, 833, 423 bp, covering 65.3% of the entire genome. The average coverage of euchromatin and heterochromatin was 58.9% and 67.3%, respectively. From this analysis, two possible genome rearrangements were identified: one in chromosome 2 (inversion) and the other in chromosome 3 (inversion and translocation). Polymorphisms (SNPs and Indels) between the two cultivars were identified from the BLAST alignments. As a result, 171,792 polymorphisms were mapped on 12 chromosomes. Among these, 30,930 polymorphisms were found in euchromatin (1 per 3,565 bp) and 140,862 were found in heterochromatin (1 per 2,737 bp). The average polymorphism density in the genome was 1 polymorphism per 2,886 bp. To facilitate the use of these data in Micro-Tom research, the BAC contig and polymorphism information are available in the TOMATOMICS database. PMID:23227037

  11. Orfandad, exilio y utopía en el pensamiento literario de Tomás Segovia

    Directory of Open Access Journals (Sweden)

    Juan Pascual Gay

    2013-07-01

    Full Text Available Este texto pretende una aproximación al desarrollo de ciertas ideas centrales presentes en la obra de Tomás Segovia: exilio, orfandad y utopía. En el caso del exilio se hablará del que se corresponde con una noción más bien abstracta antes que la histórica concreta; el estado de orfandad como un exilio radical conculcado por el reconocimiento, y la utopía como un lugar posible de ser vivido desde el respeto por el otro, por el mero hecho de ser hombre. This text aims to an approach to the development of certain central ideas present in the work of Tomás Segovia: exile, orphanhood, and utopia. In the case of the exile will discuss which corresponds to a rather abstract notion rather than the historic concrete; the State of orphanhood as a radical exile violated by the recognition, and utopia as a possible place of living out of respect on the other, by the mere fact of being a man.

  12. Availability of Micro-Tom mutant library combined with TILLING in molecular breeding of tomato fruit shelf-life.

    Science.gov (United States)

    Okabe, Yoshihiro; Asamizu, Erika; Ariizumi, Tohru; Shirasawa, Kenta; Tabata, Satoshi; Ezura, Hiroshi

    2012-06-01

    Novel mutant alleles of an ethylene receptor Solanum lycopersicum ETHYLENE RESPONSE1 (SlETR1) gene, Sletr1-1 and Sletr1-2, were isolated from the Micro-Tom mutant library by TILLING in our previous study. They displayed different levels of impaired fruit ripening phenotype, suggesting that these alleles could be a valuable breeding material for improving shelf life of tomato fruit. To conduct practical use of the Sletr1 alleles in tomato breeding, genetic complementation analysis by transformation of genes carrying each allele is required. In this study, we generated and characterized transgenic lines over-expressing Sletr1-1 and Sletr1-2. All transgenic lines displayed ethylene insensitive phenotype and ripening inhibition, indicating that Sletr1-1 and Sletr1-2 associate with the ethylene insensitive phenotype. The level of ethylene sensitivity in the seedling was different between Sletr1-1 and Sletr1-2 transgenic lines, whereas no apparent difference was observed in fruit ripening phenotype. These results suggested that it is difficult to fine-tune the extent of ripening by transgenic approach even if the weaker allele (Sletr1-2) was used. Our present and previous studies indicate that the Micro-Tom mutant library combined with TILLING could be an efficient tool for exploring genetic variations of important agronomic traits in tomato breeding.

  13. Availability of Micro-Tom mutant library combined with TILLING in molecular breeding of tomato fruit shelf-life

    Science.gov (United States)

    Okabe, Yoshihiro; Asamizu, Erika; Ariizumi, Tohru; Shirasawa, Kenta; Tabata, Satoshi; Ezura, Hiroshi

    2012-01-01

    Novel mutant alleles of an ethylene receptor Solanum lycopersicum ETHYLENE RESPONSE1 (SlETR1) gene, Sletr1-1 and Sletr1-2, were isolated from the Micro-Tom mutant library by TILLING in our previous study. They displayed different levels of impaired fruit ripening phenotype, suggesting that these alleles could be a valuable breeding material for improving shelf life of tomato fruit. To conduct practical use of the Sletr1 alleles in tomato breeding, genetic complementation analysis by transformation of genes carrying each allele is required. In this study, we generated and characterized transgenic lines over-expressing Sletr1-1 and Sletr1-2. All transgenic lines displayed ethylene insensitive phenotype and ripening inhibition, indicating that Sletr1-1 and Sletr1-2 associate with the ethylene insensitive phenotype. The level of ethylene sensitivity in the seedling was different between Sletr1-1 and Sletr1-2 transgenic lines, whereas no apparent difference was observed in fruit ripening phenotype. These results suggested that it is difficult to fine-tune the extent of ripening by transgenic approach even if the weaker allele (Sletr1-2) was used. Our present and previous studies indicate that the Micro-Tom mutant library combined with TILLING could be an efficient tool for exploring genetic variations of important agronomic traits in tomato breeding. PMID:23136532

  14. Miscellanea Herpetologica Sanctithomae, with a provisional checklist of the terrestrial herpetofauna of São Tomé, Príncipe and Annobon islands.

    Science.gov (United States)

    CerÍaco, Luis M P; Marques, Mariana P; Bauer, Aaron M

    2018-02-26

    Five problematic cases regarding the presence of reptile taxa on the island of São Tomé (Gulf of Guinea) are reviewed. These cases deal with 1) the past presence of crocodilians in the island, 2) the putative type locality of Dipsas pulverulenta Fischer, 1856, 3) the dubious presence of a mamba (genus Dendroaspis) on the island, 4) an erroneous reference to the presence of Gastropyxis smaragdina, and 5) two specimens (Psammophis lineatus and Psammophis elegans) from Carl Weiss collection, currently deposited in the Zoological Museum of Hamburg and wrongly labelled as being from São Tomé island. A provisional checklist to the terrestrial herpetofauna of the three oceanic islands of the Gulf of Guinea-São Tomé, Príncipe and Annobon-is presented in order to clarify the current numbers of the endemics of each island, as well as to review and present current research.

  15. Effects of packaging materials on the aroma stability of Thai 'tom yam' seasoning powder as determined by descriptive sensory analysis and gas chromatography-mass spectrometry.

    Science.gov (United States)

    Leelaphiwat, Pattarin; Harte, Janice B; Auras, Rafael A; Ong, Peter Kc; Chonhenchob, Vanee

    2017-04-01

    Changes in the aroma characteristics of Thai 'tom yam' seasoning powder, containing lemongrass, galangal and kaffir lime leaf, as affected by different packaging materials were assessed using quantitative descriptive analysis (QDA) and gas chromatography-mass spectrometry (GC-MS). The descriptive aroma attributes for lemongrass, galangal and kaffir lime leaf powders were developed by the QDA panel. The mixed herb and spice seasoning powder was kept in glass jars closed with different packaging materials (Nylon 6, polyethylene terephthalate (PET) and polylactic acid (PLA)) stored at 38 °C (accelerated storage condition), and evaluated by the trained QDA panel during storage for 49 days. The descriptive words for Thai 'tom yam' seasoning powder developed by the trained panelists were lemongrass, vinegary and leafy for lemongrass, galangal and kaffir lime leaf dried powder, respectively. The aroma intensities significantly (P ≤ 0.05) decreased with increased storage time. However, the intensity scores for aroma attributes were not significantly (P > 0.05) different among the packaging materials studied. The major components in Thai 'tom yam' seasoning powder, quantified by GC-MS, were estragole, bicyclo[3.1.1]heptane, β-bisabolene, benzoic acid and 2-ethylhexyl salicylate. The concentrations of major aroma compounds significantly (P ≤ 0.05) decreased with storage time. Aroma stability of Thai 'tom yam' powder can be determined by descriptive sensory evaluation and GC-MS analysis. Nylon, PET and PLA exhibited similar aroma barrier properties against key aroma compounds in Thai 'tom yam'. This information can be used for prediction of aroma loss through packaging materials during storage of Thai 'tom yam'. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  16. NMR investigations of the dual targeting peptide of Thr-tRNA synthetase and its interaction with the mitochondrial Tom20 receptor in Arabidopsis thaliana.

    Science.gov (United States)

    Ye, Weihua; Spånning, Erika; Unnerståle, Sofia; Gotthold, David; Glaser, Elzbieta; Mäler, Lena

    2012-10-01

    Most mitochondrial proteins are synthesized in the cytosol as precursor proteins containing an N-terminal targeting peptide and are imported into mitochondria through the import machineries, the translocase of the outer mitochondrial membrane (TOM) and the translocase of the inner mitochondrial membrane (TIM). The N-terminal targeting peptide of precursor proteins destined for the mitochondrial matrix is recognized by the Tom20 receptor and plays an important role in the import process. Protein import is usually organelle specific, but several plant proteins are dually targeted into mitochondria and chloroplasts using an ambiguous dual targeting peptide. We present NMR studies of the dual targeting peptide of Thr-tRNA synthetase and its interaction with Tom20 in Arabidopsis thaliana. Our findings show that the targeting peptide is mostly unstructured in buffer, with a propensity to form α-helical structure in one region, S6-F27, and a very weak β-strand propensity for Q34-Q38. The α-helical structured region has an amphiphilic character and a φχχφφ motif, both of which have previously been shown to be important for mitochondrial import. Using NMR we have mapped out two regions in the peptide that are important for Tom20 recognition: one of them, F9-V28, overlaps with the amphiphilic region, and the other comprises residues L30-Q39. Our results show that the targeting peptide may interact with Tom20 in several ways. Furthermore, our results indicate a weak, dynamic interaction. The results provide for the first time molecular details on the interaction of the Tom20 receptor with a dual targeting peptide. © 2012 The Authors Journal compilation © 2012 FEBS.

  17. Enhancing Nanos expression via the bacterial TomO protein is a conserved strategy used by the symbiont Wolbachia to fuel germ stem cell maintenance in infected Drosophila females.

    Science.gov (United States)

    Ote, Manabu; Yamamoto, Daisuke

    2018-04-27

    The toxic manipulator of oogenesis (TomO) protein has been identified in the wMel strain of Wolbachia that symbioses with the vinegar fly Drosophila melanogaster, as a protein that affects host reproduction. TomO protects germ stem cells (GSCs) from degeneration, which otherwise occurs in ovaries of host females that are mutant for the gene Sex-lethal (Sxl). We isolated the TomO homologs from wPip, a Wolbachia strain from the mosquito Culex quinquefasciatus. One of the homologs, TomO w Pip 1, exerted the GSC rescue activity in fly Sxl mutants when lacking its hydrophobic stretches. The GSC-rescuing action of the TomO w Pip 1 variant was ascribable to its abilities to associate with Nanos (nos) mRNA and to enhance Nos protein expression. The analysis of structure-activity relationships with TomO homologs and TomO deletion variants revealed distinct modules in the protein that are each dedicated to different functions, i.e., subcellular localization, nos mRNA binding or Nos expression enhancement. We propose that modular reshuffling is the basis for structural and functional diversification of TomO protein members. © 2018 Wiley Periodicals, Inc.

  18. Tomás Romay Chacón y Carlos J. Finlay Barres hitos de pensamiento cubano en salud

    Directory of Open Access Journals (Sweden)

    María Elena Macías Llanes

    Full Text Available El objetivo del texto radica en resaltar algunos elementos de pensamiento en salud de los notables médicos cubanos Tomás Romay y Carlos J. Finlay. Se analizan sus posturas y connotación acerca del nexo entre la ciencia y la sociedad. El método investigativo utilizado ha sido la revisión documental en publicaciones periódicas, libros y repositorio de tesis. Destaca en este acercamiento la conmemoración en agosto del centenario de la muerte de Finlay (La Habana, 20 de agosto de 1915. Por lo cual este sucinto trabajo constituye un homenaje a su obra y, a su vez, al ideario de vanguardia manifiesto en la labor médica de ambos hombres de ciencia.

  19. The effect of the Tom Thumb dwarfing gene on grain size and grain number of wheat (Triticum aestivum)

    International Nuclear Information System (INIS)

    Gale, M.D.; Flintham, J.E.

    1984-01-01

    The Tom Thumb dwarfing gene, Rht3, like the related genes Rht1 and Rht2 from Norin 10, has pleiotropic effects on individual ear yields, and grain protein concentrations. An experiment was conducted in which tiller number per plant and grain number per spike were restricted to ascertain whether reduced grain size and protein content are primary or secondary competitive effects in near-isogenic lines. The potential for grain growth was shown to be identical in Rht3 and rht genotypes when grain set was restricted, indicating that the primary effect of the gene is to increase spikelet fertility. Nitrogen accumulation within the grain was also affected by inter-grain competition but decreased nitrogen yields per plant indicated that reduced protein levels are, in part, a primary effect of the gene. Analysis of individual grain yields within Rht3 and rht spikes showed that the gene affected developmental 'dominance' relationships within the spike. (author)

  20. Black Humour Spaces in Cinema and Literature: Yorgos Lanthimos' The Lobster and Tom McCarthy's Satin Island

    Directory of Open Access Journals (Sweden)

    Vincenzo Maggitti

    2016-11-01

    Full Text Available Maggitti’s essay is focused on two different expressions of black humour in today’s film and literature. After commenting on a recent proposal, by the British writer Jonathan Coe, on the whereabouts of contemporary humour, the author examines a film  (The Lobster by YorgosLanthimos and a novel (Satin Island by T. McCarthy, both portraying the present world through humorous lenses, with a disrespectful attitude to an ecologically correct behaviour. In The Lobster hunting is claimed a universal role in man to animal relation whereas Tom McCarthy turns environmental disasters into acts of worthy ecologism. In his approach to humour, Maggitti draws on its anthropological turn as its most estranging function.

  1. Effective dose in two different dental CBCT Systems: NewTom VGi and Planmeca 3D Mid

    International Nuclear Information System (INIS)

    Ghaedizirgar, Mohammad; Faghihi, Reza; Paydar, Reza; Sina, Sedigheh

    2017-01-01

    Cone beam computed tomography, CBCT, is a kind of CT scanner producing conical diverging X-rays, in which a large area of a two-dimensional detector is irradiated in each rotation. Different investigations have been performed on dosimetry of dental CBCT. As there is no special protocol for dental CBCT, CT scan protocols are used for dosimetry. The purpose of this study is measurement of dose to head and neck organs in two CBCT systems, i.e. Planmeca 3D Mid (PM) and NewTom VGi (NT), using thermoluminescence dosimetry and Rando phantom. The thermoluminescent dosimetry (TLD)-100 chips were put at the position of different organs of the head and neck. Two TLD-100 chips were inserted at each position, the dose values were measured for several different field sizes, i.e. 8 x 8, 12 x 8 and 15 x 15 cm"2 for NewTom, and 10 x 10 and 20 x 17 cm"2 for Planmeca systems. According to the results, the average effective dose in PM is much more than the NT system in the same field size, because of the greater mAs values. For routine imaging protocols used for NT, the effective dose values are 70, 73 and 121 μSv for 8 x 8, 12 x 8 and 15 x 15 cm"2 field sizes, respectively. In PM, the effective dose in 10 x 10 cm"2 and 17 x 20 cm"2 is 259 and 341 μSv, respectively. (authors)

  2. Validation of the thermal code of RadTherm-IR, IR-Workbench, and F-TOM

    Science.gov (United States)

    Schwenger, Frédéric; Grossmann, Peter; Malaplate, Alain

    2009-05-01

    System assessment by image simulation requires synthetic scenarios that can be viewed by the device to be simulated. In addition to physical modeling of the camera, a reliable modeling of scene elements is necessary. Software products for modeling of target data in the IR should be capable of (i) predicting surface temperatures of scene elements over a long period of time and (ii) computing sensor views of the scenario. For such applications, FGAN-FOM acquired the software products RadTherm-IR (ThermoAnalytics Inc., Calumet, USA; IR-Workbench (OKTAL-SE, Toulouse, France). Inspection of the accuracy of simulation results by validation is necessary before using these products for applications. In the first step of validation, the performance of both "thermal solvers" was determined through comparison of the computed diurnal surface temperatures of a simple object with the corresponding values from measurements. CUBI is a rather simple geometric object with well known material parameters which makes it suitable for testing and validating object models in IR. It was used in this study as a test body. Comparison of calculated and measured surface temperature values will be presented, together with the results from the FGAN-FOM thermal object code F-TOM. In the second validation step, radiances of the simulated sensor views computed by RadTherm-IR and IR-Workbench will be compared with radiances retrieved from the recorded sensor images taken by the sensor that was simulated. Strengths and weaknesses of the models RadTherm-IR, IR-Workbench and F-TOM will be discussed.

  3. Growth analysis partitioning of assimilate in tomato plants cv. Micro-Tom submitted to nitrogen and pyraclostrobin

    Directory of Open Access Journals (Sweden)

    Emanuela Garbin Martinazzo

    2015-10-01

    Full Text Available This work aimed at comparing the growth and partitioning of assimilate in tomato plants cv. Micro-Tom subjected to nitrogen and pyraclostrobin. This substance favors the development of chloroplasts and the synthesis of chlorophyll. Tomato plants were submitted to the treatments: T1, complete nutrient solution without pyraclostrobin, T2, complete nutrient solution + pyraclostrobin, T3, ½ strength nutrient solution without N pyraclostrobin and T4, ½ strength nutrient solution N + pyraclostrobin. Plants were collected at regular intervals of seven days after transplantation throughout the crop cycle, with dry mass and leaf area being determined. From the primary data, growth analysis was carried out to calculate total dry matter (Wt, the instantaneous rates of dry matter production (Ct, relative growth (Rw e net assimilation (Ea, leaf area (Af, production rates (Ca and relative growth of leaf area index (Ra and leaf weight (Fw specific leaf area (Sa the dry matter partitioning between organs and number (Nfr and fresh fruit weight (Wfr. Plants of T1 showed higher Wt, Ct and Wfr compared to those of other treatments. However, the T2 plants exhibited similar Nfr to T1 plants, being superior to others. Also allocated on the total dry matter and at the end of the cycle, a higher percentage of dry matter in the seafood compared to T3 and T4 plants. Also they allocated relative to the total dry matter and at the end of the cycle, a higher percentage in fruits of plants to T3 and T4. The association between nitrogen and pyraclostrobin changes the growth and assimilated partition on tomato plants cv. Micro – Tom, and those submitted to ½ dose of nitrogen have a higher total dry matter and less final percentage of total dry matter in fruits , comparatively to those submitted to the association ½ dose of nitrogen and pyraclostrobin.

  4. Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes.

    Science.gov (United States)

    Vasiljev, Andreja; Ahting, Uwe; Nargang, Frank E; Go, Nancy E; Habib, Shukry J; Kozany, Christian; Panneels, Valérie; Sinning, Irmgard; Prokisch, Holger; Neupert, Walter; Nussberger, Stephan; Rapaport, Doron

    2004-03-01

    Precursor proteins of the solute carrier family and of channel forming Tim components are imported into mitochondria in two main steps. First, they are translocated through the TOM complex in the outer membrane, a process assisted by the Tim9/Tim10 complex. They are passed on to the TIM22 complex, which facilitates their insertion into the inner membrane. In the present study, we have analyzed the function of the Tim9/Tim10 complex in the translocation of substrates across the outer membrane of mitochondria. The purified TOM core complex was reconstituted into lipid vesicles in which purified Tim9/Tim10 complex was entrapped. The precursor of the ADP/ATP carrier (AAC) was found to be translocated across the membrane of such lipid vesicles. Thus, these components are sufficient for translocation of AAC precursor across the outer membrane. Peptide libraries covering various substrate proteins were used to identify segments that are bound by Tim9/Tim10 complex upon translocation through the TOM complex. The patterns of binding sites on the substrate proteins suggest a mechanism by which portions of membrane-spanning segments together with flanking hydrophilic segments are recognized and bound by the Tim9/Tim10 complex as they emerge from the TOM complex into the intermembrane space.

  5. TOMS/Nimbus-7 Total Column Ozone Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 Total Column Ozone Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  6. TOMS/Nimbus-7 UV Aerosol Index Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 UV Aerosol Index Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  7. Obraz hilsneriády ve vzájemné korespondenci Tomáše Garrigua Masaryka a Josefa Adolfa Bulovy

    Czech Academy of Sciences Publication Activity Database

    Květová, Miroslava

    2017-01-01

    Roč. 9, č. 1 (2017), s. 51-84 ISSN 1803-9448 Institutional support: RVO:67985921 Keywords : Masaryk, Tomáš Garrigue * Bulova, Josef Adolf * correspondence Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  8. TOMS/Earth Probe UV Reflectivity Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe UV Reflectivity Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The shortname for this Level-3...

  9. Overseas dispersal of Hyperolius reed frogs from Central Africa to the oceanic islands of Sao Tomé and Príncipe

    Czech Academy of Sciences Publication Activity Database

    Bell, R. C.; Drewes, R. C.; Channing, A.; Gvoždík, Václav; Kielgast, J.; Lötters, S.; Stuart, B. L.; Zamudio, K. R.

    2015-01-01

    Roč. 42, č. 1 (2015), s. 65-75 ISSN 0305-0270 Institutional support: RVO:68081766 Keywords : Central Africa * Congo River * Gulf of Guinea * Hyperolius * long -distance dispersal * oceanic island * biogeography * phylogeography * Príncipe * Sao Tomé * species tree Subject RIV: EG - Zoology Impact factor: 3.997, year: 2015

  10. TOMS/Earth Probe UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The shortname for this...

  11. TOMS/Nimbus-7 UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  12. TOMS/Earth Probe UV-B Erythemal Local Noon Irradiance Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe UV-B Erythemal Local Noon Irradiance Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The...

  13. TOMS/Earth Probe Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The shortname for this...

  14. TOMS/Nimbus-7 UV-B Erythemal Local Noon Irradiance Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 UV-B Erythemal Local Noon Irradiance Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone...

  15. Tomáš Garrigue Masaryk v českých diskusích o literárním realismu

    Czech Academy of Sciences Publication Activity Database

    Hrdina, Martin

    2014-01-01

    Roč. 17, č. 1 (2014), s. 183-203 ISSN 1213-2144 R&D Projects: GA ČR GPP406/12/P839 Institutional support: RVO:68378068 Keywords : Masaryk, Tomáš Garrigue * Zola, Émile * literary realism * naturalism * empirical aesthetics Subject RIV: AJ - Letters, Mass-media, Audiovision

  16. Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin.

    Science.gov (United States)

    Lazarou, Michael; Jin, Seok Min; Kane, Lesley A; Youle, Richard J

    2012-02-14

    Mutations in the mitochondrial kinase PINK1 and the cytosolic E3 ligase Parkin can cause Parkinson's disease. Damaged mitochondria accumulate PINK1 on the outer membrane where, dependent on kinase activity, it recruits and activates Parkin to induce mitophagy, potentially maintaining organelle fidelity. How PINK1 recruits Parkin is unknown. We show that endogenous PINK1 forms a 700 kDa complex with the translocase of the outer membrane (TOM) selectively on depolarized mitochondria whereas PINK1 ectopically targeted to the outer membrane retains association with TOM on polarized mitochondria. Inducibly targeting PINK1 to peroxisomes or lysosomes, which lack a TOM complex, recruits Parkin and activates ubiquitin ligase activity on the respective organelles. Once there, Parkin induces organelle selective autophagy of peroxisomes but not lysosomes. We propose that the association of PINK1 with the TOM complex allows rapid reimport of PINK1 to rescue repolarized mitochondria from mitophagy, and discount mitochondrial-specific factors for Parkin translocation and activation. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. Theory of Mind (ToM) in Children with Autism or Typical Development: Links between Eye-Reading and False Belief Understanding

    Science.gov (United States)

    Peterson, Candida C.; Slaughter, Virginia

    2009-01-01

    Previous research shows that high-functioning children with autism are slow to pass "litmus" false belief tests of ToM but how this may relate to other aspects of mindreading (e.g., discerning thoughts from facial expressions) is less clear, partly for methodological reasons. Thus the joint methodological and conceptual goals of this…

  18. TOMS/Nimbus-7 Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  19. Ignacio Arellano, El ingenio de Lope de Vega. Escolios a las «Rimas humanas y divinas del licenciado Tomé de Burguillos»

    Directory of Open Access Journals (Sweden)

    Bienvenido Morros Mestres

    2014-01-01

    Full Text Available Review of Ignacio Arellano,El ingenio de Lope de Vega. Escolios a las «Rimas humanas y divinas del licenciado Tomé de Burguillos», IDEA/IGAS, New York, 2012, 305 pp. ISBN: 978-1-938795-84-8.

  20. Analysis of Ozone (O3 and Erythemal UV (EUV measured by TOMS in the equatorial African belt

    Directory of Open Access Journals (Sweden)

    Øyvind Frette

    2010-03-01

    Full Text Available We presented time series of total ozone column amounts (TOCAs and erythemal UV (EUV doses derived from measurements by TOMS (Total Ozone Mapping Spectrometer instruments on board the Nimbus-7 (N7 and the Earth Probe (EP satellites for three locations within the equatorial African belt for the period 1979 to 2000. The locations were Dar-es-Salaam (6.8° S, 39.26° E in Tanzania, Kampala (0.19° N, 32.34° E in Uganda, and Serrekunda (13.28° N, 16.34° W in Gambia. Equatorial Africa has high levels of UV radiation, and because ozone shields UV radiation from reaching the Earth’s surface, there is a need to monitor TOCAs and EUV doses. In this paper we investigated the trend of TOCAs and EUV doses, the effects of annual and solar cycles on TOCAs, as well as the link between lightning and ozone production in the equatorial African belt. We also compared clear-sky simulated EUV doses with the corresponding EUV doses derived from TOMS measurements. The TOCAs were found to vary in the ranges 243 DU − 289 DU, 231 DU − 286 DU, and 236 DU − 296 DU, with mean values of 266.9 DU, 260.9 DU, and 267.8 DU for Dar-es-Salaam, Kampala and Serrekunda, respectively. Daily TOCA time series indicated that Kampala had the lowest TOCA values, which we attributed to the altitude effect. There were two annual ozone peaks in Dar-es-Salaam and Kampala, and one annual ozone peak in Serrekunda. The yearly TOCA averages showed an oscillation within a five-year period. We also found that the EUV doses were stable at all three locations for the period 1979−2000, and that Kampala and Dar-es-Salaam were mostly cloudy throughout the year, whereas Serrekunda was mostly free from clouds. It was also found that clouds were among the major factors determining the level of EUV reaching the Earth´s surface. Finally, we noted that during rainy seasons, horizontal advection effects augmented by lightning activity may be responsible for enhanced ozone production in the tropics.

  1. Arte y revolución: Sobre los fotomontajes olvidados de Tomás Maldonado Art and revolution: on the forgotten photomontages of Tomás Maldonado

    Directory of Open Access Journals (Sweden)

    Daniela Lucena

    2012-08-01

    Full Text Available Este artículo presenta un análisis sobre los fotomontajes realizados por el artista Tomás Maldonado entre 1946 y 1947 para Orientación, el periódico oficial del Partido Comunista Argentino. Estas producciones eran desconocidas (o silenciadas por los historiadores del arte argentino hasta los inicios de la investigación que emprendí en el año 2003 y que se materializó en mi tesis doctoral (2010, e incluso hasta hace muy poco tiempo no se incluían en el repertorio de obras del artista. Desde la perspectiva aquí propuesta, en cambio,los fotomontajes de Maldonado constituyen dos intervenciones cruciales para abordar el intenso vínculo entre arte, revolución y política que atraviesa el proyecto de la vanguardia de arte concreto argentina. Por un lado, porque remiten a la militancia de varios miembros de la Asociación Arte ConcretoInvención en las filas del comunismo local. Por otro, porque son producciones en las cuales es posible observar la estrecha relación existente entre la propuesta del concretismo argentino impulsado por Maldonado y el programa puesto en marcha por las vanguardias soviéticas en los años posteriores a la revolución bolchevique

  2. A Comparison of Seasonal and Interannual Variability of Soil Dust Aerosols Over the Atlantic Ocean as Inferred by the Toms AI and AVHRR AOT Retrievals

    Science.gov (United States)

    Cakmur, R. V.; Miller, R. L.; Tegen, Ina; Hansen, James E. (Technical Monitor)

    2001-01-01

    The seasonal cycle and interannual variability of two estimates of soil (or 'mineral') dust aerosols are compared: Advanced Very High Resolution Radiometer (AVHRR) aerosol optical thickness (AOT) and Total Ozone Mapping Spectrometer (TOMS) aerosol index (AI), Both data sets, comprising more than a decade of global, daily images, are commonly used to evaluate aerosol transport models. The present comparison is based upon monthly averages, constructed from daily images of each data set for the period between 1984 and 1990, a period that excludes contamination from volcanic eruptions. The comparison focuses upon the Northern Hemisphere subtropical Atlantic Ocean, where soil dust aerosols make the largest contribution to the aerosol load, and are assumed to dominate the variability of each data set. While each retrieval is sensitive to a different aerosol radiative property - absorption for the TOMS AI versus reflectance for the AVHRR AOT - the seasonal cycles of dust loading implied by each retrieval are consistent, if seasonal variations in the height of the aerosol layer are taken into account when interpreting the TOMS AI. On interannual time scales, the correlation is low at most locations. It is suggested that the poor interannual correlation is at least partly a consequence of data availability. When the monthly averages are constructed using only days common to both data sets, the correlation is substantially increased: this consistency suggests that both TOMS and AVHRR accurately measure the aerosol load in any given scene. However, the two retrievals have only a few days in common per month so that these restricted monthly averages have a large uncertainty. Calculations suggest that at least 7 to 10 daily images are needed to estimate reliably the average dust load during any particular month, a threshold that is rarely satisfied by the AVHRR AOT due to the presence of clouds in the domain. By rebinning each data set onto a coarser grid, the availability of

  3. Renewable energies in the French DOM-TOM : a study of the costs and benefits of transitioning from fossil fuels to renewable energies in the French Départements d’Outre Mer et Territoires d’Outre Mer

    OpenAIRE

    Stanley-Smith, Adam P.

    2010-01-01

    The French Départements d’Outre Mer et Territoires d’Outre Mer (DOM-TOM) are not the most populous region of France. Nor are they the most prosperous, the most important, or even centers of industrial production. Rather, the DOM-TOM possessions have a unique value in French culture: they represent the past glory of the state and its people, and the courage that lead French explorers and settlers to roam the world. Unfortunately, the DOM-TOM represents an ever growing burden upon...

  4. Changes in melatonin levels in transgenic 'Micro-Tom' tomato overexpressing ovine AANAT and ovine HIOMT genes.

    Science.gov (United States)

    Wang, Lin; Zhao, Yu; Reiter, Russel J; He, Changjiu; Liu, Guoshi; Lei, Qiong; Zuo, Bixiao; Zheng, Xiao Dong; Li, Qingtian; Kong, Jin

    2014-03-01

    In animals, the melatonin biosynthesis pathway has been well defined after the isolation and identification of the four key genes that are involved in the conversion of tryptophan to melatonin. In plants, there are special alternative catalyzing steps, and plant genes share very low homology with the animal genes. It was of interest to examine the phenotype of transgenic Micro-Tom tomato plants overexpressing the homologous sheep oAANAT and oHIOMT genes responsible for the last two steps of melatonin synthesis. The oAANAT transgenic plants have higher melatonin levels and lower indoleacetic acid (IAA) contents than control due to the competition for tryptophan, the same precursor for both melatonin and IAA. Therefore, the oAANAT lines lose the 'apical dominance' inferring that melatonin likely lacks auxin activity. The significantly higher melatonin content in oHIOMT lines than oAANAT lines provides new proof for the important role of ASMT in plant melatonin synthesis. In addition, the enhanced drought tolerance of oHIOMT lines will also be an important contribution for plant engineering. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. As inovações de Tom Zé na linguagem da canção popular dos anos 1970

    Directory of Open Access Journals (Sweden)

    Herom Vargas

    2012-12-01

    Full Text Available O objetivo deste artigo é discutir alguns aspectos da experimentação do compositor brasileiro Tom Zé em três de seus cinco discos lançados nos anos 1970, dentro de um cenário de exceção institucional por conta da ditadura militar e de expansão das indústrias culturais. Do cantor, serão tratadas canções dos discos: Se o caso é chorar (Continental - 1972, Todos os olhos (Continental - 1973 e Estudando o samba (Continental - 1975. A noção básica de experimentação utilizada é de Umberto Eco (1970. Outro conceito para a discussão do experimentalismo é o de “canção crítica”, desenvolvido por S.C. Naves (2010. Como horizonte teórico, a canção popular será tratada como “texto semiótico”, conforme a semiótica da cultura de I.M. Lótman (1996. Os aspectos de inovação serão analisados internamente à própria linguagem híbrida da canção (letra, canto, música e performance e nas relações externas entre canção e contexto cultural.

  6. The Rg1 allele as a valuable tool for genetic transformation of the tomato 'Micro-Tom' model system

    Directory of Open Access Journals (Sweden)

    Quecini Vera

    2010-10-01

    Full Text Available Abstract Background The cultivar Micro-Tom (MT is regarded as a model system for tomato genetics due to its short life cycle and miniature size. However, efforts to improve tomato genetic transformation have led to protocols dependent on the costly hormone zeatin, combined with an excessive number of steps. Results Here we report the development of a MT near-isogenic genotype harboring the allele Rg1 (MT-Rg1, which greatly improves tomato in vitro regeneration. Regeneration was further improved in MT by including a two-day incubation of cotyledonary explants onto medium containing 0.4 μM 1-naphthaleneacetic acid (NAA before cytokinin treatment. Both strategies allowed the use of 5 μM 6-benzylaminopurine (BAP, a cytokinin 100 times less expensive than zeatin. The use of MT-Rg1 and NAA pre-incubation, followed by BAP regeneration, resulted in high transformation frequencies (near 40%, in a shorter protocol with fewer steps, spanning approximately 40 days from Agrobacterium infection to transgenic plant acclimatization. Conclusions The genetic resource and the protocol presented here represent invaluable tools for routine gene expression manipulation and high throughput functional genomics by insertional mutagenesis in tomato.

  7. Emergencia de la conciencia intelectiva. La teoría creacionista según Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Lorenzo Vicente Burgoa

    2016-10-01

    Full Text Available La pregunta «¿de dónde venimos?" sigue siendo de interés, para saber qué somos y hacia dónde vamos ... Una vez aceptada la evolución transespecífica de los seres vivos, actualmente todos o casi todos aceptan el origen filogenético del cuerpo humano. Pero hay notables reticencias y hasta serias dificultades para aceptar ese mismo origen para el alma humana. Esas dificultades provienen tanto de un supuesto dogma acerca de la creación del alma directamente por Dios, como de posiciones metafísicas muy serias, entre las que cabe destacar la argumentación de Tomás de Aquino. El autor de este trabajo, dejando de lado el aspecto teológico -aunque señalando de paso su duda fundada respecto de la existencia de tal dogma creacionista- se enfrenta a los argumentos metafísicos, desde las mismas bases sistemáticas en que tales argumentos parecen fundarse. Su conclusión es que esos argumentos no son decisivos; y que, por tanto, se puede y se debe seguir buscando un origen filogenético común para el hombre en su totalidad, dejando de lado el dualismo antropológico accidentalista, de tipo platónico y racionalista.

  8. Máscaras a la deriva: acerca de la narrativa de Tomás de Mattos

    Directory of Open Access Journals (Sweden)

    José Manuel González Álvarez

    2014-06-01

    Full Text Available El presente artículo pretende indagar en aspectos estructurales y temáticos de la novela La fragata de las máscaras (1996 del narrador uruguayo Tomás de Mattos. Tomando como punto de partida el Benito Cereno de Herman Melville, De Mattos construye un texto denso y laberíntico que no desmerece la prosa del escritor norteamericano. Aprovechando los cabos sueltos dejados por Melville en Benito Cereno, el uruguayo osa reescribir el episodio del motín acaecido pero invirtiendo las voces y dando protagonismo a los esclavos. Erige así una novela sugestiva en su planteamiento y compleja en su estructura, con un auténtico homenaje a la noción de transtextualidad en sentido lato, acuñada por Gérard Genette; intertextos, paratextos e hipertextos y continuas puestas en abismo se entrecruzan para conformar una novela polifónica pero no por ello estrictamente posmoderna, si nos atenemos al pensamiento del autor, muy distante del descreimiento que gobierna otros textos de la nueva novela histórica uruguaya coetáneos al que aquí analizamos.

  9. Multi year changes of Aerosol Optical Depth in the monsoon region of the Indian Ocean since 1986 as seen in the AVHRR and TOMS data

    Directory of Open Access Journals (Sweden)

    J. P. George

    2008-02-01

    Full Text Available Aerosol Optical Depth (AOD data based on AVHRR and TOMS was analyzed to find out the changes in the Indian Ocean from 1981 to 2004. Four regions covering Indian Ocean north of 10° S were studied in detail. The results strongly suggest that the mean value of AOD in these regions decreased from 1986–1990 to 1995–1999. The Arabian Sea and Bay of Bengal show increase thereafter whereas in the equatorial part it decreased further, during 2000–2004. The drop in AOD from the first to second period is evident in AVHRR and TOMS in the case of the Arabian Sea (North West Indian Ocean. The decrease in this case is prominent in summer. These results in general agree with the recently reported global decrease in AOD, "global brightening" and also the reversal of trend in some of the anthropogenic emissions.

  10. Los principios del método teológico de Santo Tomás a partir de la noción de sacra doctrina

    OpenAIRE

    Scarabino, Juan Lisandro

    2012-01-01

    Con el presente artículo queremos señalar los principios del método teológico de Santo Tomás. Dicho objetivo lo abordamos desde la noción de sacra doctrina, la cual es hoy en día es una noción olvidada y de ahí proviene la dificultad para su correcta comprensión. De ahí que se tienda a identificarla con la teología, restringiéndola fuertemente. Para Santo Tomás es una noción muy importante. Por esta razón toda la primera cuestión de la Suma Teológica gira sobre ella, pues la...

  11. Effect of object location on the density measurement and Hounsfield conversion in a NewTom 3G cone beam computed tomography unit.

    Science.gov (United States)

    Lagravère, M O; Carey, J; Ben-Zvi, M; Packota, G V; Major, P W

    2008-09-01

    The purpose of this study was to determine the effect of an object's location in a cone beam CT imaging chamber (CBCT-NewTom 3G) on its apparent density and to develop a linear conversion coefficient for Hounsfield units (HU) to material density (g cm(-3)) for the NewTom 3G Scanner. Three cylindrical models of materials with different densities were constructed and scanned at five different locations in a NewTom 3G Volume Scanner. The average HU value for each model at each location was obtained using two different types of software. Next, five cylinders of different known densities were scanned at the exact centre of a NewTom 3G Scanner. The collected data were analysed using the same two types of software to determine a standard linear relationship between density and HU for each type of software. There is no statistical significance of location of an object within the CBCT scanner on determination of its density. A linear relationship between the density of an object and the HU of a scan was rho = 0.001(HU)+1.19 with an R2 value of 0.893 (where density, rho, is measured in g cm(-3)). This equation is to be used on a range between 1.42 g cm(-3) and 0.4456 g cm(-3). A linear relationship can be used to determine the density of materials (in the density range of bone) from the HU values of a CBCT scan. This relationship is not affected by the object's location within the scanner itself.

  12. Optimisation of tomato Micro-tom regeneration and selection on glufosinate/Basta and dependency of gene silencing on transgene copy number.

    Science.gov (United States)

    Khuong, Thi Thu Huong; Crété, Patrice; Robaglia, Christophe; Caffarri, Stefano

    2013-09-01

    An efficient protocol of transformation and selection of transgenic lines of Micro-tom, a widespread model cultivar for tomato, is reported. RNA interference silencing efficiency and stability have been investigated and correlated with the number of insertions. Given its small size and ease of cultivation, the tomato (Solanum lycopersicon) cultivar Micro-tom is of widespread use as a model tomato plant. To create and screen transgenic plants, different selectable markers are commonly used. The bar marker carrying the resistance to the herbicide glufosinate/Basta, has many advantages, but it has been little utilised and with low efficiency for identification of tomato transgenic plants. Here we describe a procedure for accurate selection of transgenic Micro-tom both in vitro and in soil. Immunoblot, Southern blot and phenotypic analyses showed that 100 % of herbicide-resistant plants were transgenic. In addition, regeneration improvement has been obtained by using 2 mg/l Gibberellic acid in the shoot elongation medium; rooting optimisation on medium containing 1 mg/l IAA allowed up to 97 % of shoots developing strong and very healthy roots after only 10 days. Stable transformation frequency by infection of leaf explants with Agrobacterium reached 12 %. Shoots have been induced by combination of 1 mg/l zeatin-trans and 0.1 mg/l IAA. Somatic embryogenesis of cotyledon on medium containing 1 mg/l zeatin + 2 mg/l IAA is described in Micro-tom. The photosynthetic psbS gene has been used as reporter gene for RNA silencing studies. The efficiency of gene silencing has been found equivalent using three different target gene fragments of 519, 398 and 328 bp. Interestingly, silencing efficiency decreased from T0 to the T3 generation in plants containing multiple copies of the inserted T-DNA, while it was stable in plants containing a single insertion.

  13. Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

    DEFF Research Database (Denmark)

    Medina-Gomez, Carolina; Kemp, John P; Dimou, Niki L

    2017-01-01

    bone mineral density loci: WNT4, GALNT3, MEPE, CPED1/WNT16, TNFSF11, RIN3, and PPP6R3/LRP5. Variants in the TOM1L2/SREBF1 locus exert opposing effects TB-LM and TBLH-BMD, and have a stronger association with the former trait. We show that SREBF1 is expressed in murine and human osteoblasts, as well...

  14. Apostolate of the laity: a re-discovery of holistic post-war missiology in Scotland, with reference to the ministry of Tom Allan

    OpenAIRE

    Forsyth, Alexander Craig

    2014-01-01

    This thesis offers principles for Christian mission in the present Western milieu derived from a retrieval of the missiology in post-war Scotland of Tom Allan. Allan was a minister, evangelist and theologian of particular public prominence in Scotland and beyond in the period from 1946 to 1964. His missiology focused upon the ‘apostolate of the laity’ through the ‘contextualisation’ of Christianity and Church. It was drawn from diverse, rich sources in Scottish and European theolo...

  15. Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.

    Directory of Open Access Journals (Sweden)

    Andras Franko

    Full Text Available To better understand molecular mechanisms regulating changes in metabolism, as observed e.g. in diabetes or neuronal disorders, the function of mitochondria needs to be precisely determined. The usual isolation methods such as differential centrifugation result in isolates of highly variable quality and quantity. To fulfill the need of a reproducible isolation method from solid tissues, which is suitable to handle parallel samples simultaneously, we developed a protocol based on anti-TOM22 (translocase of outer mitochondrial membrane 22 homolog antibody-coupled magnetic beads. To measure oxygen consumption rate in isolated mitochondria from various mouse tissues, a traditional Clark electrode and the high-throughput XF Extracellular Flux Analyzer were used. Furthermore, Western blots, transmission electron microscopic and proteomic studies were performed to analyze the purity and integrity of the mitochondrial preparations. Mitochondrial fractions isolated from liver, brain and skeletal muscle by anti-TOM22 magnetic beads showed oxygen consumption capacities comparable to previously reported values and little contamination with other organelles. The purity and quality of isolated mitochondria using anti-TOM22 magnetic beads was compared to traditional differential centrifugation protocol in liver and the results indicated an obvious advantage of the magnetic beads method compared to the traditional differential centrifugation technique.

  16. Resolução e apreensão de princípios em Tomás de Aquino [Resolution and apprehension of principles in Aquinas

    Directory of Open Access Journals (Sweden)

    Matheus Pazos

    2016-06-01

    Full Text Available O escopo do presente artigo consiste em investigar a função da resolução na apreensão de princípios em Tomás de Aquino. Para tanto, examino o sentido da resolução do ente efetuada por Tomás em De veritate, q. 1, a. 1. Com o intuito de elucidar esse extrato textual, tenho por objetivo explicitar como Tomás associa o emprego da resolução, entendida como método próprio da razão humana, com a apreensão intelectual do ente que, de acordo com Tomás, é o princípio geral sem o qual todo conhecimento humano encontrar-se-ia desprovido de fundamentação.

  17. Tom Tabor, the owner of Tabor Communications, presents Wolfgang von Rüden with the Editors Choice Award of HPCwire, which was awarded to CERN for its commitment to educating the public about high-performance computing.

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Tom Tabor, the owner of Tabor Communications, presents Wolfgang von Rüden with the Editors Choice Award of HPCwire, which was awarded to CERN for its commitment to educating the public about high-performance computing.

  18. A base sócio-histórica na construção do protagonista em As Aventuras de Tom Sawyer

    Directory of Open Access Journals (Sweden)

    Ângela Tavares Nates Moreira

    2015-06-01

    Full Text Available A obra The Adventures of Tom Sawyer, escrita pelo autor norte americano Samuel Langhorne Clemens, mais conhecido pelo pseudônimo Mark Twain, é considerada, hoje, a narrativa que inaugurou a literatura infanto-juvenil, no século XIX. Essa narrativa ganha maior expressividade devido a sua escrita de caráter regionalista utilizado pelo autor. Com a publicação de As Aventuras de Tom Sawyer, Mark Twain percorre o ambiente literário, com traços marcados pelo humor, pelo Realismo e pelo Regionalismo. Este trabalho objetiva analisar os fragmentos da fala de Tom e aspectos sócio-históricos de uma época de mudanças.  A finalidade é considerar o processo de transição do protagonista, dentro do romance. Desse modo, foram selecionados alguns fragmentos que revelam pontos Realistas. Após a leitura da obra, foram verificados e extraídos fragmentos representativos do jovem protagonista, tais como crenças religiosas, compreensão de mundo e valores morais. O filtro analítico se pauta no trabalho de teóricos como Bakhtin (2010, Watt (2010 e Blair (1967, entre outros, que contribuíram com informações sobre o desenvolvimento político, cultural e religioso das famílias americanas do Centro-Oeste dos Estados Unidos do século XIX. Serão abordadas as teorias sobre o personagem, a partir das reflexões de Gancho (2006 e Candido (2007. Os vários fragmentos analisados permitiram-nos chegar à conclusão sobre o modo como a transição do jovem protagonista foi influenciada, quais as características que revelam suas preferências e opiniões, e, por acréscimo, verificar que muitas dessas respostas poderão ser constatadas em conformidade com o período da época que, “irrevogavelmente”, são considerados intrínsecos na vida de Tom Sawyer.Palavras-chave: protagonista; regionalismo; realismo; Tom Sawyer.

  19. Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum) cultivar Micro-Tom, a reference system for the Solanaceae genomics.

    Science.gov (United States)

    Aoki, Koh; Yano, Kentaro; Suzuki, Ayako; Kawamura, Shingo; Sakurai, Nozomu; Suda, Kunihiro; Kurabayashi, Atsushi; Suzuki, Tatsuya; Tsugane, Taneaki; Watanabe, Manabu; Ooga, Kazuhide; Torii, Maiko; Narita, Takanori; Shin-I, Tadasu; Kohara, Yuji; Yamamoto, Naoki; Takahashi, Hideki; Watanabe, Yuichiro; Egusa, Mayumi; Kodama, Motoichiro; Ichinose, Yuki; Kikuchi, Mari; Fukushima, Sumire; Okabe, Akiko; Arie, Tsutomu; Sato, Yuko; Yazawa, Katsumi; Satoh, Shinobu; Omura, Toshikazu; Ezura, Hiroshi; Shibata, Daisuke

    2010-03-30

    The Solanaceae family includes several economically important vegetable crops. The tomato (Solanum lycopersicum) is regarded as a model plant of the Solanaceae family. Recently, a number of tomato resources have been developed in parallel with the ongoing tomato genome sequencing project. In particular, a miniature cultivar, Micro-Tom, is regarded as a model system in tomato genomics, and a number of genomics resources in the Micro-Tom-background, such as ESTs and mutagenized lines, have been established by an international alliance. To accelerate the progress in tomato genomics, we developed a collection of fully-sequenced 13,227 Micro-Tom full-length cDNAs. By checking redundant sequences, coding sequences, and chimeric sequences, a set of 11,502 non-redundant full-length cDNAs (nrFLcDNAs) was generated. Analysis of untranslated regions demonstrated that tomato has longer 5'- and 3'-untranslated regions than most other plants but rice. Classification of functions of proteins predicted from the coding sequences demonstrated that nrFLcDNAs covered a broad range of functions. A comparison of nrFLcDNAs with genes of sixteen plants facilitated the identification of tomato genes that are not found in other plants, most of which did not have known protein domains. Mapping of the nrFLcDNAs onto currently available tomato genome sequences facilitated prediction of exon-intron structure. Introns of tomato genes were longer than those of Arabidopsis and rice. According to a comparison of exon sequences between the nrFLcDNAs and the tomato genome sequences, the frequency of nucleotide mismatch in exons between Micro-Tom and the genome-sequencing cultivar (Heinz 1706) was estimated to be 0.061%. The collection of Micro-Tom nrFLcDNAs generated in this study will serve as a valuable genomic tool for plant biologists to bridge the gap between basic and applied studies. The nrFLcDNA sequences will help annotation of the tomato whole-genome sequence and aid in tomato functional

  20. Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum cultivar Micro-Tom, a reference system for the Solanaceae genomics

    Directory of Open Access Journals (Sweden)

    Kikuchi Mari

    2010-03-01

    Full Text Available Abstract Background The Solanaceae family includes several economically important vegetable crops. The tomato (Solanum lycopersicum is regarded as a model plant of the Solanaceae family. Recently, a number of tomato resources have been developed in parallel with the ongoing tomato genome sequencing project. In particular, a miniature cultivar, Micro-Tom, is regarded as a model system in tomato genomics, and a number of genomics resources in the Micro-Tom-background, such as ESTs and mutagenized lines, have been established by an international alliance. Results To accelerate the progress in tomato genomics, we developed a collection of fully-sequenced 13,227 Micro-Tom full-length cDNAs. By checking redundant sequences, coding sequences, and chimeric sequences, a set of 11,502 non-redundant full-length cDNAs (nrFLcDNAs was generated. Analysis of untranslated regions demonstrated that tomato has longer 5'- and 3'-untranslated regions than most other plants but rice. Classification of functions of proteins predicted from the coding sequences demonstrated that nrFLcDNAs covered a broad range of functions. A comparison of nrFLcDNAs with genes of sixteen plants facilitated the identification of tomato genes that are not found in other plants, most of which did not have known protein domains. Mapping of the nrFLcDNAs onto currently available tomato genome sequences facilitated prediction of exon-intron structure. Introns of tomato genes were longer than those of Arabidopsis and rice. According to a comparison of exon sequences between the nrFLcDNAs and the tomato genome sequences, the frequency of nucleotide mismatch in exons between Micro-Tom and the genome-sequencing cultivar (Heinz 1706 was estimated to be 0.061%. Conclusion The collection of Micro-Tom nrFLcDNAs generated in this study will serve as a valuable genomic tool for plant biologists to bridge the gap between basic and applied studies. The nrFLcDNA sequences will help annotation of the

  1. Population Genetics of the São Tomé Caecilian (Gymnophiona: Dermophiidae: Schistometopum thomense) Reveals Strong Geographic Structuring

    Science.gov (United States)

    Stoelting, Ricka E.; Measey, G. John; Drewes, Robert C.

    2014-01-01

    Islands provide exciting opportunities for exploring ecological and evolutionary mechanisms. The oceanic island of São Tomé in the Gulf of Guinea exhibits high diversity of fauna including the endemic caecilian amphibian, Schistometopum thomense. Variation in pigmentation, morphology and size of this taxon over its c. 45 km island range is extreme, motivating a number of taxonomic, ecological, and evolutionary hypotheses to explain the observed diversity. We conducted a population genetic study of S. thomense using partial sequences of two mitochondrial DNA genes (ND4 and 16S), together with morphological examination, to address competing hypotheses of taxonomic or clinal variation. Using Bayesian phylogenetic analysis and Spatial Analysis of Molecular Variance, we found evidence of four geographic clades, whose range and approximated age (c. 253 Kya – 27 Kya) are consistent with the spread and age of recent volcanic flows. These clades explained 90% of variation in ND4 (φCT = 0.892), and diverged by 4.3% minimum pairwise distance at the deepest node. Most notably, using Mismatch Distributions and Mantel Tests, we identified a zone of population admixture that dissected the island. In the northern clade, we found evidence of recent population expansion (Fu's Fs = −13.08 and Tajima's D = −1.80) and limited dispersal (Mantel correlation coefficient = 0.36, p = 0.01). Color assignment to clades was not absolute. Paired with multinomial regression of chromatic data, our analyses suggested that the genetic groups and a latitudinal gradient together describe variation in color of S. thomense. We propose that volcanism and limited dispersal ability are the likely proximal causes of the observed genetic structure. This is the first population genetic study of any caecilian and demonstrates that these animals have deep genetic divisions over very small areas in accordance with previous speculations of low dispersal abilities. PMID:25171066

  2. Evaluating Ultraviolet Radiation Exposures Determined from TOMS Satellite Data at Sites of Amphibian Declines in Central and South America

    Science.gov (United States)

    Middleton, Elizabeth M.; Smith, David E. (Technical Monitor)

    2000-01-01

    Many amphibian species have experienced substantial population declines, or have disappeared altogether, during the last several decades at a number of amphibian census sites in Central and South America. This study addresses the use of satellite-derived trends in solar ultraviolet-B (UV-B; 280-320 nm) radiation exposures at these sites over the last two decades, and is intended to demonstrate a role for satellite observations in determining whether UV-B radiation is a contributing factor in amphibian declines. UV-B radiation levels at the Earth's surface were derived from the Total Ozone Mapping Spectrometer (TOMS) satellite data, typically acquired daily since 1979. These data were used to calculate the daily erythemal (sunburning) UV-B, or UV-B(sub ery), exposures at the latitude, longitude, and elevation of each of 20 census sites. The annually averaged UV-B(sub ery) dose, as well as the maximum values, have been increasing in both Central and South America, with higher levels received at the Central American sites. The annually averaged UV-B(sub ery) exposures increased significantly from 1979-1998 at all 11 Central American sites examined (r(exp 2) = 0.60 - 0.79; P= 6750 J/sq m*d) to the annual UV-B(sub ery) total has increased from approx. 5% to approx. 15% in Central America over the 19 year period, but actual daily exposures for each species are unknown. Synergy among UV-B radiation and other factors, especially those associated with alterations of water chemistry (e.g., acidification) in aqueous habitats is discussed. These findings justify further research concerning whether UV-B(sub ery) radiation plays a role in amphibian population declines and extinctions.

  3. Videnskabsretorik eller tom retorik

    DEFF Research Database (Denmark)

    Jensen, Leif Becker

    2005-01-01

    Artiklen omhandler videnskabsretorik såvel i den videnskabelige undersøgelse som i fremlæggelsen inden for forskellige paradigmer, herunder argumetnation set i lyset af Toulmins argumentationsmodel....

  4. Response to Tom Cobb

    Science.gov (United States)

    Nation, Paul

    2016-01-01

    In this article Paul Nation responds to Thomas Cobb's "Numbers or Numerology? A Response to Nation (2014) and McQuillan (2016)" (EJ1117024). Nation begins by clarifying his own position on vocabulary learning and goes on to highlight points made in Cobb's article with which he is in agreement, while drawing from his 2014 article,…

  5. Trouble in Toms River

    Science.gov (United States)

    Lugg, Catherine A.; Tooms, Autumn K.

    2011-01-01

    Drawing on a recent New Jersey Supreme Court decision (2007), this case addresses a school district's responsibility regarding homophobic bullying, school culture, and the rights of lesbian, gay, bisexual, and transgender students to be free of discrimination.

  6. Up-to-date concentrations of long-lived artificial radionuclides in the Tom and Ob rivers in the area influenced by discharges from Siberian chemical combine

    International Nuclear Information System (INIS)

    Nikitin, A.I.; Kryshev, I.I.; Bashkirov, N.I.; Valetova, N.K.; Dunaev, G.E.; Kabanov, A.I.; Katrich, I.Yu; Krutovsky, A.O.; Nikitin, V.A.; Petrenko, G.I.; Polukhina, A.M.; Selivanova, G.V.; Shkuro, V.N.

    2012-01-01

    The Siberian Chemical Combine (SCC) is located in Seversk (formerly known as Tomsk-7) in the Tomsk Region of the Russian Federation. The main contribution of radionuclides in the SCC process water discharged into the Tom River was from the single-pass reactors, now removed from service (the last SCC reactor was shutdown on June 5, 2008). The data on the concentrations of 90 Sr, 137 Cs, 239,240 Pu and other artificial radionuclides in water, bottom sediments and flood-plain soils of the Tom and Ob rivers from Tomsk to the confluence of the rivers, are presented and discussed. The results of measurements carried out after shutdown of the last SCC single-pass reactor indicated no radiologically significant consequences of SCC activities for the studied water environment compartments. Contemporary activity concentrations of long-lived artificial radionuclides 3 H, 90 Sr, 137 Cs and 239,240 Pu in river water were below the intervention levels established by current regulations of the Russian Federation for these radionuclides. The results of 3 H analysis in water from the Tom and Samuska rivers demonstrated no inflow of contaminated formation water to surface water from the sites where liquid radioactive wastes of the SCC were injected below the surface. However, the density of flood-plain soil contamination by long-lived 137 Cs in the area influenced by SCC liquid discharges was higher than regional technogenic background. There were local flood-plain areas contaminated not only by 137 Cs, but also other gamma-emitters, such as 60 Co and 152 Eu.

  7. La iglesia de los santos Ildefonso y Tomás de Villanueva en Roma: un monumento barroco a la pietas hispanica

    Directory of Open Access Journals (Sweden)

    González Tornel, Pablo

    2015-03-01

    Full Text Available In 1667 the construction of the Hospice of Saints Ildefonso and Tomás de Villanueva began on the Roman Via Sistina. The headquarters of the Augustinian Recollects in Rome took on a particular architectural configuration directly inspired by Francesco Borromini’s Chapel of the Three Kings and a very concrete iconography linked to the political situation during the second half of the 17th century. Thus the church was decorated to create a monument to the Immaculate Conception with images of the Loreto litany adorning its walls, reinforced by paintings of the Virgins of Copacabana and Guadalupe inside. All of this, combined with the dedication of the building to Saint Tomás de Villanueva (canonized in 1658, turns the temple into a celebration of the pietas hispanica in an area of the Holy City scene of clashes for power between France and Spain.En 1667 se pone la primera piedra del Hospicio de los santos Ildefonso y Tomás de Villanueva en la Via Sistina romana. La sede de la orden de los agustinos recoletos en Roma toma una particular configuración arquitectónica, directamente inspirada en la Capilla de los Reyes Magos de Francesco Borromini, y una muy definida iconografía vinculada con la situación política de la segunda mitad del siglo XVII. Así, la iglesia se erige en un monumento a la Inmaculada Concepción concretado en las imágenes de la letanía lauretana que ornan sus muros y reforzado por las pinturas de las vírgenes de Copacabana y Guadalupe en su interior. Todo ello, junto a la advocación a Santo Tomás de Villanueva, canonizado en 1658, convierte el templo en un alegato a la pietas hispanica en un área de la ciudad que fue escenario de los enfrentamientos entre Francia y España.

  8. HIV-1 infection, response to treatment and establishment of viral latency in a novel humanized T cell-only mouse (TOM) model.

    Science.gov (United States)

    Honeycutt, Jenna B; Wahl, Angela; Archin, Nancie; Choudhary, Shailesh; Margolis, David; Garcia, J Victor

    2013-10-24

    The major targets of HIV infection in humans are CD4⁺ T cells. CD4⁺ T cell depletion is a hallmark of AIDS. Previously, the SCID-hu thy/liv model was used to study the effect of HIV on thymopoeisis in vivo. However, these mice did not develop high levels of peripheral T cell reconstitution and required invasive surgery for infection and analysis. Here, we describe a novel variant of this model in which thy/liv implantation results in systemic reconstitution with human T cells in the absence of any other human hematopoietic lineages. NOD/SCID-hu thy/liv and NSG-hu thy/liv mice were created by implanting human fetal thymus and liver tissues under the kidney capsule of either NOD/SCID or NSG mice. In contrast to NOD/SCID-hu thy/liv mice that show little or no human cells in peripheral blood or tissues, substantial systemic human reconstitution occurs in NSG-hu thy/liv. These mice are exclusively reconstituted with human T cells (i.e. T-cell only mice or TOM). Despite substantial levels of human T cells no signs of graft-versus-host disease (GVHD) were noted in these mice over a period of 14 months. TOM are readily infected after parenteral exposure to HIV-1. HIV replication is sustained in peripheral blood at high levels and results in modest reduction of CD4⁺ T cells. HIV-1 replication in TOM responds to daily administration of combination antiretroviral therapy (ART) resulting in strong suppression of virus replication as determined by undetectable viral load in plasma. Latently HIV infected resting CD4⁺ T cells can be isolated from suppressed mice that can be induced to express HIV ex-vivo upon activation demonstrating the establishment of latency in vivo. NSG-hu thy/liv mice are systemically reconstituted with human T cells. No other human lymphoid lineages are present in these mice (i.e. monocytes/macrophages, B cells and DC are all absent). These T cell only mice do not develop GVHD, are susceptible to HIV-1 infection and can efficiently maintain virus

  9. La Chartreuse de Parme,Tom Jones et Vanity Fair : la représentation autoconsciente dans trois stades de développement

    OpenAIRE

    Vågslid, Gudfrid

    2007-01-01

    En résumé INTRODUCTION Pour ce mémoire j ai choisi trois uvres réalistes, notamment The History of Tom Jones, a Foundling publié par Henry Fielding en 1749, La Chartreuse de Parme de Stendhal (1839) et Vanity Fair, a novel without a hero de William Makepeace Thackeray qui est paru en feuilleton en 1847-48. Je me concentrerai sur la Chartreuse et me servirai d exemples des deux autres uvres pour mettre en relief celle de Stendhal. Stendhal et Fielding partageaient « le m...

  10. 6 June 2008 - Chancellor F. Tomàs Vert, University of Valencia, visiting ATLAS control room and experimental area with Collaboration Spokesperson P. Jenni.

    CERN Multimedia

    Mona Schweizer

    2008-01-01

    6 June 2008 - Chancellor F. Tomàs Vert, University of Valencia, visiting ATLAS control room and experimental area with Collaboration Spokesperson P. Jenni. Other participants: Prof. Francisco José Botella, Director, Instituto de Fisica Corpuscular, University of València and CSIC Prof. José Peñarrocha, Dean, Faculty of Physics Prof. Antonio Ferrer, Instituto de Fisica Corpuscular, University of València and CSIC Prof. Antonio Pich, University of València, Member of IFIC (CSIC - Univ. València), Coordinator of CPAN, Spanish National Centre for Particle, Astroparticle and Nuclear Physics.

  11. El modelo universitario europeo en Asia: la universidad de Santo Tomás de Manila (1611) y la civilización filipina

    OpenAIRE

    Donoso Jiménez, Isaac

    2008-01-01

    La introducción del modelo universitario europeo en Asia se produjo a finales del siglo XVI por medio de la doctrina dominica en el Archipiélago Filipino, teniendo como pilar fundamental el desarrollo de la imprenta tipográfica. En 1611 se dará carta de naturaleza a la Universidad de Santo Tomás, considerada como la primera universidad de Asia, que desarrollará una labor determinante en la definición moderna del concepto de Civilización Filipina. The introduction of the European university...

  12. Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats.

    Science.gov (United States)

    Gültiken, Nilgün; Aslan, Selim; Ay, Serhan Serhat; Gülbahar, Mustafa Yavuz; Thuróczy, Julianna; Koldaş, Ece; Kaya, Duygu; Fındık, Murat; Schäfer-Somi, Sabine

    2017-02-01

    Objectives The aim of the study was to evaluate the efficacy of a 4.7 mg deslorelin implant in tom cats. Methods Nine mature male cats were included in the deslorelin group and five cats in the control group. Before the study started, all cats were confirmed to have distinct sexually dimorphic behaviour. Blood samples were taken on the implantation day, at day 7 and at day 15, then monthly, in order to measure serum dihydrotestosterone (DHT) and 17beta(β)-oestradiol concentrations. The deslorelin group (n = 9) was divided into two subgroups: five cats (cats 1-5) were neutered in the postimplantation period during suppression of sexually dimorphic behaviour, and four cats (cats 6-9) were neutered after re-expression of sexually dimorphic behaviour. The control group cats (n = 5) were castrated without administration of the implant. Results Sexually dimorphic behaviours ceased within a mean ± SD of 13-58 days (23.30 ± 14.17) after implantation. DHT concentration decreased within 30 days. The mean duration of suppression was 26.5 ± 7.42 months and reactivation coincided with increased DHT values reaching preimplantation concentrations within 1 month. 17β-oestradiol concentrations significantly correlated with DHT concentrations ( P tom cats without any side effects and with full reversibility; however, duration of suppression is highly individual.

  13. Wolbachia Protein TomO Targets nanos mRNA and Restores Germ Stem Cells in Drosophila Sex-lethal Mutants.

    Science.gov (United States)

    Ote, Manabu; Ueyama, Morio; Yamamoto, Daisuke

    2016-09-12

    Wolbachia, endosymbiotic bacteria prevalent in invertebrates, manipulate their hosts in a variety of ways: they induce cytoplasmic incompatibility, male lethality, male-to-female transformation, and parthenogenesis. However, little is known about the molecular basis for host manipulation by these bacteria. In Drosophila melanogaster, Wolbachia infection makes otherwise sterile Sex-lethal (Sxl) mutant females capable of producing mature eggs. Through a functional genomic screen for Wolbachia genes with growth-inhibitory effects when expressed in cultured Drosophila cells, we identified the gene WD1278 encoding a novel protein we call toxic manipulator of oogenesis (TomO), which phenocopies some of the Wolbachia effects in Sxl mutant D. melanogaster females. We demonstrate that TomO enhances the maintenance of germ stem cells (GSCs) by elevating Nanos (Nos) expression via its interaction with nos mRNA, ultimately leading to the restoration of germ cell production in Sxl mutant females that are otherwise without GSCs. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Relaciones entre masculinidades: Controversia en La cabaña del tío Tom Relations among Masculinities: Controversy in Uncle Tom’s Cabin

    Directory of Open Access Journals (Sweden)

    Luis Fernando Gómez R.

    2007-01-01

    Full Text Available The American novel Uncle Tom’s Cabin, written by Harriet Beecher-Stowe, has caused historical debate because of its notion of masculinity between white men and African-American slaves in the antebellum period. The description of these two antagonist forces are said to be defined by the author on extreme foundations of sentimentalist and romantic racialism that seem to distort the real objective events related to slavery in America . Beecher-Stowe was condemned by both white and black races because of the denunciation she makes of slavery as a hegemonic male institution. This article examines this polemic in Uncle Tom’s cabin, based on the sociologist R.W. Connell’s theory of relations among masculinities. From this theory, the article argues that while whites’ masculinity is determined by a sense of power based on hegemony, complicity, and subordination, blacks’, represented by uncle Tom, is portrayed as adopting weak submission and resigned marginalization. As Uncle Tom’s Cabin is the inspiration of a historical reality, this article also studies the novel in relation to factual events in which the ideals of hegemonic masculinity established slavery as a powerful institution in America .La cabaña del tío Tom, escrita por Beecher-Stowe ha causado debate histórico debido a su noción de masculinidad entre el hombre blanco y el hombre africano durante el período de la esclavitud. Se dice que la autora describe estas dos fuerzas antagónicas con fundamentos extremos de sentimentalismo y romanticismo racial, que parecen distorsionar los hechos reales relacionados con la esclavitud en Estados Unidos. Ambas razas condenaron a la novelista por la denuncia que hace de la esclavitud como una institución hegemónicamente masculina. En este artículo se examina tal polémica en La cabaña del tío Tom, a la luz de la teoría que propone el sociólogo R.W. Connell sobre relaciones entre masculinidades. A partir de ésta, se argumenta el

  15. FORMAS DE TRATAMENTO EM TRADUÇÕES DE “THE ADVENTURES OF TOM SAWYER”: RELAÇÕES SOCIAIS E AFETIVAS

    Directory of Open Access Journals (Sweden)

    Giselle Olivia Mantovani Dal Corno

    2015-02-01

    Full Text Available Mark Twain is a renowned realist author, known by his colloquial style and local colorism. In the novel “The adventures of Tom Sawyer”, he manages to depict oral regional language in the lines of his characters. Address forms used by characters contribute to the representation of social relations in the book. From the analysis of a few dialogs in the original text in English and their translations into Portuguese, this paper will discuss not only oral language indexes but also the ways how the choice of lexical items for addressing reveal different degrees of affectivity and social hierarchy. Some cases of loss in translation are registered as well as one case of domestication, in the terms of Venutti (1998.

  16. Análise florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará.

    OpenAIRE

    BOLFE, E. L.; BATISTELLA, M.

    2012-01-01

    O objetivo deste trabalho foi analisar a composição florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará. Os dados dendrométricos foram obtidos por inventário em 40 parcelas amostrais, com três unidades cada uma, no total de 120 unidades de 10x10 m. Foi inventariada a média de 1.424,3 indivíduos por hectare, pertencentes a 27 famílias e a 54 espécies. Tendo-se considerado a variabilidade dos estágios vegetativos, os diferentes sistemas silviagrícolas (SAF) foram divididos em q...

  17. Caracterización del perfil de los estudiantes de Negocios Internacionales de la Universidad Santo Tomás, sede Bogotá

    Directory of Open Access Journals (Sweden)

    Myriam Soraya Suárez R.

    2013-01-01

    Full Text Available Los estudios sobre el perfil de los estudiantes universitarios se han llevado a cabo permanentemente, debido a que las universidades requieren saber con qué estudiantes cuentan y cómo estos requieren ser formados, de acuerdo con las necesidades actua - les del mercado laboral y las necesidades sociales del contexto en el cual se encuentran inmersos. Esta investigación sobre la caracterización del perfil de los estudiantes de la Facultad de Negocios Internacionales de la Universidad Santo Tomás, sede Bogotá, determinó los aspectos biográficos, sociodemográficos, proyecto de vida, perfil educativo y profesional, competencias y uso del tiempo libre, con el fin de describir las motivaciones, intereses y percepciones, lo cual permitió tener un conocimiento holístico de los estudiantes y de todos los aspectos involucrados en su formación.

  18. Análise florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará

    Directory of Open Access Journals (Sweden)

    Édson Luis Bolfe

    2011-10-01

    Full Text Available O objetivo deste trabalho foi analisar a composição florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará. Os dados dendrométricos foram obtidos por inventário em 40 parcelas amostrais, com três unidades cada uma, no total de 120 unidades de 10x10 m. Foi inventariada a média de 1.424,3 indivíduos por hectare, pertencentes a 27 famílias e a 54 espécies. Tendo-se considerado a variabilidade dos estágios vegetativos, os diferentes sistemas silviagrícolas (SAF foram divididos em quatro classes hierárquicas: SAF 1, SAF 2, SAF 3, e SAF 4, para estabelecer um sistema de classificação passível de ser utilizado em outras avaliações de campo e em classificações digitais por meio do sensoriamento remoto. Espécies observadas em outros sistemas da região amazônica também foram relevantes para este estudo, especialmente Theobroma cacao, T. grandiflorum e Euterpe oleracea que, juntas, apresentaram médias de frequência relativa de 51%, densidade relativa de 69,2%, dominância relativa de 50,1% e índice de valor de importância de 56,8%. Os dados médios de diversidade florística, abundância, área basal e valor de importância indicam os sistemas silviagrícolas da região de Tomé-Açu como sistemas de produção com potencial econômico e ambiental, se adotado manejo adequado e racional.

  19. Dosimetry of 3 CBCT devices for oral and maxillofacial radiology: CB Mercuray, NewTom 3G and i-CAT.

    Science.gov (United States)

    Ludlow, J B; Davies-Ludlow, L E; Brooks, S L; Howerton, W B

    2006-07-01

    Cone beam computed tomography (CBCT), which provides a lower dose, lower cost alternative to conventional CT, is being used with increasing frequency in the practice of oral and maxillofacial radiology. This study provides comparative measurements of effective dose for three commercially available, large (12'') field-of-view (FOV), CBCT units: CB Mercuray, NewTom 3G and i-CAT. Thermoluminescent dosemeters (TLDs) were placed at 24 sites throughout the layers of the head and neck of a tissue-equivalent human skull RANDO phantom. Depending on availability, the 12'' FOV and smaller FOV scanning modes were used with similar phantom positioning geometry for each CBCT unit. Radiation weighted doses to individual organs were summed using 1990 (E(1990)) and proposed 2005 (E(2005 draft)) ICRP tissue weighting factors to calculate two measures of whole-body effective dose. Dose as a multiple of a representative panoramic radiography dose was also calculated. For repeated runs dosimetry was generally reproducible within 2.5%. Calculated doses in microSv [corrected] (E(1990), E(2005 draft)) were NewTom3G (45, 59), i-CAT (135, 193) and CB Mercuray (477, 558). These are 4 to 42 times greater than comparable panoramic examination doses (6.3 microSv [corrected] 13.3 mSv). Reductions in dose were seen with reduction in field size and mA and kV technique factors. CBCT dose varies substantially depending on the device, FOV and selected technique factors. Effective dose detriment is several to many times higher than conventional panoramic imaging and an order of magnitude or more less than reported doses for conventional CT.

  20. Prevalência de enteroparisitos na populaçao urbana de São Tomé - RN - estudo comparativo de um decênio

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Moreira Campos

    1982-12-01

    Full Text Available Objetivando a obtenção de variáveis relacionadas aos fatores sócio-econômicos e sanitários no período de dez (10 anos, os autores colheram resultados sobre a prevalência de enteroparasitas na população urbana de São Tomé, Rio Grande do Norte, cujos dados foram coletados entre 09 a 27 de julho de 1979, empregando o método da sedimentação espontânea (Hoffmann, Pons e Janer, através de exames realizados em 826 amostras de fezes, com uma positividade de565 para as diversas parasitoses intestinais e correspondendo a uma prevalência de 68,4% em função das condições ambientais que, embora melhoradas, concorrem no processo de disseminação de helmintoses e protozooses, além de outras patologias.In view of socio-economic and sanitary changes during ten (10 years, the authors gathered data on the prevaíence of enteroparasites in the urban population of São Tomé, Rio Grande do Norte. They collected from July 9 to July 27, 1979, 826 faecal samples which they examined using the spontaneous sedimentation method (Hoffmann, Pons, and Janer. 565 were positive for the various intestinal parasites, corresponding to a prevaíence of 68,4%. Although environmetal conditions have improved, they still contributed to the dissemination intestinal protozoal and helminthic infections.

  1. Meer proeven nodig om effect van hogere F-scatterwaarde te achterhalen : diffuus glas komt in de fase van fine-tuning (interview met Silke Hemming en Tom Dueck)

    OpenAIRE

    Kierkels, T.; Hemming, S.; Dueck, T.A.

    2014-01-01

    Diffuus glas is over vijftien jaar de standaard. Wie nu nieuw bouwt, heeft veel goede redenen om voor diffuus te kiezen en vrijwel geen om het te laten, zeggen Silke Hemming en Tom Dueck van Wageningen UR Glastuinbouw. De inzichten in het nut van diffuus licht én de technische ontwikkelingen schrijden nog elk jaar voort. Een update.

  2. Meer proeven nodig om effect van hogere F-scatterwaarde te achterhalen : diffuus glas komt in de fase van fine-tuning (interview met Silke Hemming en Tom Dueck)

    NARCIS (Netherlands)

    Kierkels, T.; Hemming, S.; Dueck, T.A.

    2014-01-01

    Diffuus glas is over vijftien jaar de standaard. Wie nu nieuw bouwt, heeft veel goede redenen om voor diffuus te kiezen en vrijwel geen om het te laten, zeggen Silke Hemming en Tom Dueck van Wageningen UR Glastuinbouw. De inzichten in het nut van diffuus licht én de technische ontwikkelingen

  3. The Role of Physical Context, Verbal Skills, Non-Parental Care, Social Support, and Type of Parental Discipline in the Development of ToM Capacity in Five-Year-Old Children

    Science.gov (United States)

    Galende, Nuria; de Miguel, Manuel Sanchez; Arranz, Enrique

    2011-01-01

    The aim of this study was to analyze the influence of family context on the performance of 5-year-old children (N = 70) in theory of mind (ToM) tasks. The children's performances were assessed during individual sessions held at school. Children's verbal skills were assessed using the Peabody picture vocabulary test (PPVT). Interviews were also…

  4. Wave activity (planetary, tidal throughout the middle atmosphere (20-100km over the CUJO network: Satellite (TOMS and Medium Frequency (MF radar observations

    Directory of Open Access Journals (Sweden)

    A. H. Manson

    2005-02-01

    Full Text Available Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT is studied using combinations of ground-based (GB and satellite instruments (2000-2002. The relatively new MFR (medium frequency radar at Platteville (40° N, 105° W has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity comprises systems at London (43° N, 81° W, Platteville (40° N, 105° W, Saskatoon (52° N, 107° W, Wakkanai (45° N, 142° E and Yamagawa (31° N, 131° E. It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14° at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP TOMS (Total Ozone Mapping Spectrometer and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability. Climatologies of ozone and winds/tides involving frequency versus time (wavelet contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km heights. Both direct planetary wave (PW propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric and MLT wave motions and their

  5. Wave activity (planetary, tidal) throughout the middle atmosphere (20-100km) over the CUJO network: Satellite (TOMS) and Medium Frequency (MF) radar observations

    Science.gov (United States)

    Manson, A. H.; Meek, C. E.; Chshyolkova, T.; Avery, S. K.; Thorsen, D.; MacDougall, J. W.; Hocking, W.; Murayama, Y.; Igarashi, K.

    2005-02-01

    Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT) is studied using combinations of ground-based (GB) and satellite instruments (2000-2002). The relatively new MFR (medium frequency radar) at Platteville (40° N, 105° W) has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity) comprises systems at London (43° N, 81° W), Platteville (40° N, 105° W), Saskatoon (52° N, 107° W), Wakkanai (45° N, 142° E) and Yamagawa (31° N, 131° E). It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14°) at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP) TOMS (Total Ozone Mapping Spectrometer) and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability. Climatologies of ozone and winds/tides involving frequency versus time (wavelet) contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km) heights. Both direct planetary wave (PW) propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric and MLT wave motions and their

  6. Wave activity (planetary, tidal throughout the middle atmosphere (20-100km over the CUJO network: Satellite (TOMS and Medium Frequency (MF radar observations

    Directory of Open Access Journals (Sweden)

    A. H. Manson

    2005-02-01

    Full Text Available Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT is studied using combinations of ground-based (GB and satellite instruments (2000-2002. The relatively new MFR (medium frequency radar at Platteville (40° N, 105° W has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity comprises systems at London (43° N, 81° W, Platteville (40° N, 105° W, Saskatoon (52° N, 107° W, Wakkanai (45° N, 142° E and Yamagawa (31° N, 131° E. It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14° at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP TOMS (Total Ozone Mapping Spectrometer and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability.

    Climatologies of ozone and winds/tides involving frequency versus time (wavelet contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km heights. Both direct planetary wave (PW propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric

  7. Intraperitoneal chemotherapy for advanced ovarian and peritoneal cancers in patients following interval debulking surgery or primary cytoreductive surgery: Tom Baker Cancer Centre experience from 2006 to 2009.

    Science.gov (United States)

    Nelson, Gregory; Lucero, Carlos Aspe; Chu, Pamela; Nation, Jill; Ghatage, Prafull

    2010-03-01

    To describe our experience with cisplatin- and paclitaxel-based IP chemotherapy in patients treated initially with either neoadjuvant chemotherapy and interval debulking surgery (IDS) or primary cytoreductive surgery (PCRS). We performed a retrospective review of the records of 67 patients (38 IDS, 29 PCRS) enrolled in the intraperitoneal (IP) chemotherapy program at the Tom Baker Cancer Centre between 2006 and 2009. Information pertaining to patient demographics, IP chemotherapy toxicity, and catheter complications was extracted, and the median time to recurrence was calculated. Most patients in the study were aged 50 to 70 years and had a diagnosis of stage III serous ovarian cancer. Overall, 295/393 IP cycles (75%) were successfully administered. The proportion of patients completing six cycles of chemotherapy in the IDS and PCRS groups was 53% and 59%, respectively. Frequent (> 25%) Grade 1 to 2 chemotherapy toxicities included fatigue, peripheral neuropathy, and nausea. Catheter complications were observed in 34% of patients (23/67). The recurrence rates for patients completing four or more cycles of IP chemotherapy in the IDS and PCRS groups were 58% and 35%, respectively, with the median time to recurrence approximately one year. Although IP chemotherapy is well tolerated in both IDS and PCRS patients, the median time to recurrence is shorter than expected.

  8. The influence of secondary reconstruction slice thickness on NewTom 3G cone beam computed tomography-based radiological interpretation of sheep mandibular condyle fractures.

    Science.gov (United States)

    Sirin, Yigit; Guven, Koray; Horasan, Sinan; Sencan, Sabri; Bakir, Baris; Barut, Oya; Tanyel, Cem; Aral, Ali; Firat, Deniz

    2010-11-01

    The objective of this study was to examine the diagnostic accuracy of the different secondary reconstruction slice thicknesses of cone beam computed tomography (CBCT) on artificially created mandibular condyle fractures. A total of 63 sheep heads with or without condylar fractures were scanned with a NewTom 3G CBCT scanner. Multiplanar reformatted (MPR) views in 0.2-mm, 1-mm, 2-mm, and 3-mm secondary reconstruction slice thicknesses were evaluated by 7 observers. Inter- and intraobserver agreements were calculated with weighted kappa statistics. The receiver operating characteristic (ROC) curve analysis was used to statistically compare the area under the curve (AUC) of each slice thickness. The kappa coefficients varied from fair and to excellent. The AUCs of 0.2-mm and 1-mm slice thicknesses were found to be significantly higher than those of 2 mm and 3 mm for some type of fractures. CBCT was found to be accurate in detecting all variants of fractures at 0.2 mm and 1 mm. However, 2-mm and 3-mm slices were not suitable to detect fissure, complete, and comminuted types of mandibular condyle fractures. Copyright © 2010 Mosby, Inc. All rights reserved.

  9. DE-MYTHOLOGIZING THE BARD: APPROPRIATION OF SHAKESPEARE IN TOM STOPPARD’S DOGG’S HAMLET, CAHOOT’S MACBETH

    Directory of Open Access Journals (Sweden)

    Ifeta Ciric-Fazlija

    2014-11-01

    Full Text Available One of the most entrenched myths that dramatic authors need to contest and adjust to is the Shakespeare myth, a long-lasting and all-pervasive influence that Shakespeare’s name and texts have exerted since the late 16th century, being perceived as “represent[ing] truths that transcend particular circumstances” (Sinfield, 1998: 129. In order to be actively involved in the “making of culture” (Sinfield, 1998: 128 and for the purpose of establishing and (redefining one’s own position within and against the canonical (transnational texts, many British dramatists, including Tom Stoppard, have alluded to, quoted, or incorporated portions of Shakespeare’s plays within their own, or even reconstituted them completely. This paper discusses the manner in which Stoppard appropriates Shakespeare’s Hamlet and Macbeth – probably his best known and most frequently staged and adapted tragedies – in order to question the importance of both the author and his work within the context of contemporary culture and society.

  10. Subclinical Enteric Parasitic Infections and Growth Faltering in Infants in São Tomé, Africa: A Birth Cohort Study

    Science.gov (United States)

    Garzón, Marisol; Seixas, Jorge; Papoila, Ana Luísa; Alves, Marta

    2018-01-01

    The associations between enteric pathogenic parasites and growth in infants in São Tomé were explored using a refined anthropometric approach to recognize early growth faltering. A birth cohort study was conducted with follow-up to 24 months of age. Microscopic examination for protozoa and soil-transmitted helminths was performed. Anthropometric assessments included: z-scores for weight-for-length (WLZ), length-for-age (LAZ), weight (WAVZ) and length velocities (LAVZ), length-for-age difference (LAD), and wasting and stunting risk (≤−1 SD). Generalized additive mixed effects regression models were used to explore the associations between anthropometric parameters and enteric parasitic infections and cofactors. A total of 475 infants were enrolled, and 282 completed the study. The great majority of infants were asymptomatic. Giardia lamblia was detected in 35.1% of infants in at least one stool sample, helminths in 30.4%, and Cryptosporidium spp. in 14.7%. Giardia lamblia and helminth infections were significantly associated with mean decreases of 0.10 in LAZ and 0.32 in LAD, and of 0.16 in LAZ and 0.48 in LAD, respectively. Cryptosporidium spp. infection was significantly associated with a mean decrease of 0.43 in WAVZ and 0.55 in LAVZ. The underestimated association between subclinical parasitic enteric infections and mild growth faltering in infants should be addressed in public health policies. PMID:29621166

  11. Genome-wide transcriptomic analysis of BR-deficient Micro-Tom reveals correlations between drought stress tolerance and brassinosteroid signaling in tomato.

    Science.gov (United States)

    Lee, Jinsu; Shim, Donghwan; Moon, Suyun; Kim, Hyemin; Bae, Wonsil; Kim, Kyunghwan; Kim, Yang-Hoon; Rhee, Sung-Keun; Hong, Chang Pyo; Hong, Suk-Young; Lee, Ye-Jin; Sung, Jwakyung; Ryu, Hojin

    2018-06-01

    Brassinosteroids (BRs) are plant steroid hormones that play crucial roles in a range of growth and developmental processes. Although BR signal transduction and biosynthetic pathways have been well characterized in model plants, their biological roles in an important crop, tomato (Solanum lycopersicum), remain unknown. Here, cultivated tomato (WT) and a BR synthesis mutant, Micro-Tom (MT), were compared using physiological and transcriptomic approaches. The cultivated tomato showed higher tolerance to drought and osmotic stresses than the MT tomato. However, BR-defective phenotypes of MT, including plant growth and stomatal closure defects, were completely recovered by application of exogenous BR or complementation with a SlDWARF gene. Using genome-wide transcriptome analysis, 619 significantly differentially expressed genes (DEGs) were identified between WT and MT plants. Several DEGs were linked to known signaling networks, including those related to biotic/abiotic stress responses, lignification, cell wall development, and hormone responses. Consistent with the higher susceptibility of MT to drought stress, several gene sets involved in responses to drought and osmotic stress were differentially regulated between the WT and MT tomato plants. Our data suggest that BR signaling pathways are involved in mediating the response to abiotic stress via fine-tuning of abiotic stress-related gene networks in tomato plants. Copyright © 2018. Published by Elsevier Masson SAS.

  12. Inseguridad ciudadana y diferenciación social en el nivel microbarrial: el caso del sector Santo Tomás, Santiago de Chile

    Directory of Open Access Journals (Sweden)

    Alejandra Lunecke

    2016-01-01

    Full Text Available En la periferia de la ciudad de Santiago se observan zonas de viviendas sociales que se caracterizan por una alta concentración de precariedades económicas y materiales, segregación espacial, procesos de debilitamiento del tejido comunitario y altos niveles de inseguridad, esto último por la presencia de grupos vinculados a la criminalidad. En tal contexto, a partir de una investigación realizada en el sector Santo Tomás de la zona sur de Santiago de Chile, se analiza cómo incide en los procesos de debilitamiento del tejido social, la percepción de inseguridad asociada al delito y la violencia, en un medio de pobreza guetizada. Para ello se pone énfasis en las prácticas discursivas de los vecinos, las que dan cuenta de los juicios de valor existentes respecto de "lo peligroso" y "lo desviado". Se discute cómo dichos juicios refuerzan las dinámicas de distinción social existentes en el nivel micro barrial y se alimentan de ellas.

  13. La Universidad Santo Tomás y su contribución en el campo de la educación a distancia en Colombia

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    Blanca Aurora Pita Torres

    2006-06-01

    Full Text Available La Universidad Santo Tomás ha contribuido en el cambio de la Educación Abierta y a Distancia en Colombia desde el año 1975 con diferentes programas tanto en Educación como en Ciencias y Tecnologías, cumpliendo así 31 años de experiencia en esta modalidad y consolidándose históricamente como la Institución Educativa con más prestigio e historia del país. La Vicerrectoría de Universidad Abierta y a Distancia, encargada de esta modalidad orienta toda su labor educativa en el conocimiento contextualizado, en la docencia, la ciencia y la tecnología, la investigación y lo valida en la proyección social que tiene como principios fundamentales: la persona humana que busca realizar un proyecto de vida, el saber para el servicio y el compromiso en la búsqueda del bie ncomún; al mismo tiempo que responde a las urgencia de hoy y a las demandas y posibilidades nacionales e internacionales.

  14. La ratio legis en la teología de Suarez y Santo Tomás: Una propuesta de comparación

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    Sebastián Contreras

    2012-01-01

    Full Text Available El presente trabajo intenta profundizar en las nociones de ley de dos de los más importantes teólogos escolásticos:Tomás de Aquino y Francisco Suárez. Sabemos que el Eximio pretende dar sentido e inteligencia a las palabras del Aquinatense. Usualmente se ha marcado el voluntarismo y distancia que toma Suárez con respecto a la teologia del Maestro Angélico, motivo por el cual hemos querido bosquejar una posible continuidad entre ambos doctores de la teologia escolástica: todo a partir del análisis del concepto de imperium.This paper tries deeper into the notions of law of two of the most important scholastics: Aquinas and Suarez. We know that Suarez tries give sense and intelligence at the Aquinas' words. Usually we mark the voluntarism and the distance that Suarez takes over the Aquinas' theology; for this we wanted outline a possible continuity between the two doctors of scholastic theology: everything from the analysis of the concept of imperium.

  15. Identification of multiple PEPC isogenes in leaves of the facultative Crassulacean acid metabolism (CAM) plant Kalanchoe blossfeldiana Poelln. cv. Tom Thumb.

    Science.gov (United States)

    Gehrig, H; Taybi, T; Kluge, M; Brulfert, J

    1995-12-27

    In the facultative Crassulacean Acid Metabolism (CAM) plant Kulanchoe blossfeldiana cv. Tom Thumb, CAM can be induced by short-day treatment or water deficiency stress. From young leaves of well-watered and water-stressed individuals of this plant, cDNA clones coding for a partial sequence of the key enzyme of CAM, phosphoenolpyruvate carboxylase, were isolated after transcription of mRNA. cDNA polymorphism was established by enzyme restriction profiles and sequencing data. Four PEPC isogenes could be shown to exist in K. blossfeldiana forming two gene pairs, with 95%-98% homology inside and only 75% between the pairs. One cDNA sequence pair having a length of 1113 bp and an open reading frame of 371 AA was identified as PEPC isoform specific for the C3 state, whereas the pair having a length of 1116 bp and an open reading frame of 372 AA could be attributed to the CAM state. These results were confirmed by Southern Blot hybridization.

  16. Proyección científica de las ideas de Tomás Romay sobre la vacuna de la viruela en la inclusa madrileña

    Directory of Open Access Journals (Sweden)

    Ramírez Martín, Susana María

    2002-12-01

    Full Text Available This paper is about scientific and medical activities of Dr Tomás Romay Chacón. He was a pioneer of the fight agianst smallpox in America. We present here a breef biography of Dr. Romay and a document about vaccination against smallpox in La Habana.

    En el artículo se pone de manifiesto la trayectoria científica y médica del Dr. Tomás Romay y Chacón. Este médico habanero es un ejemplo de lucha contra las viruelas en América. Su actividad científica no se limitó a la isla de Cuba, sino que su saber llegó hasta la Inclusa Madrileña. A esta institución benéfica llegaron sus escritos en el año 1813.

  17. El Atlas Geográfico de España de Tomás López: Análisis mediante SIG de las poblaciones del «Reyno de Jaén» (1787)

    OpenAIRE

    Martínez García, Josefina; Manzano Augliario, Francisco; San Antonio Gomez, Jose Carlos de

    2012-01-01

    El catastro es el inventario de la riqueza de un país, los primeros avances en este sentido fueron identificar las poblaciones existentes y su ubicación geográfica. En este trabajo se analiza el trabajo del cartógrafo Tomás López, primero enmarcando su vida y obra, y posteriormente se analiza Atlas Geográfico de España (AGE) de Tomás López en su edición de 1804 y en concreto la hoja n.º 64 correspondiente al Reyno de Jaén y cuya elaboración data de 1787. Para ello se propone una metodología d...

  18. PREFACE: Polycrystal Modelling with Experimental Integration: A Symposium Honoring Carlos Tomé (San Diego, CA, USA, February 27-March 3 2011) Polycrystal Modelling with Experimental Integration: A Symposium Honoring Carlos Tomé (San Diego, CA, USA, February 27-March 3 2011)

    Science.gov (United States)

    Lebensohn, Ricardo A.

    2012-03-01

    This special issue contains selected contributions from invited speakers to the 'Polycrystal Modelling with Experimental Integration: A Symposium Honoring Carlos Tomé', held as part of the 2011 TMS Annual Meeting and Exhibition, that took place on February 27-March 3, 2011 in San Diego, CA, USA. This symposium honored the remarkable contributions of Dr Carlos N Tomé to the field of mechanical behavior of polycrystalline materials, on the occasion of his 60th birthday. Throughout his career, Dr Tomé has pioneered the theoretical and numerical development of models of polycrystal mechanical behavior, with emphasis on the role played by texture and microstructure on the anisotropic behavior of engineering materials. His many contributions have been critical in establishing a strong connection between models and experiments, and in bridging different scales in the pursuit of robust multiscale models with experimental integration. Among his achievements, the numerical codes that Dr Tomé and co-workers have developed are extensively used in the materials science and engineering community as predictive tools for parameter identification, interpretation of experiments, and multiscale calculations in academia, national laboratories and industry. The symposium brought together materials scientists and engineers to address current theoretical, computational and experimental issues related to microstructure-property relationships in polycrystalline materials deforming in different regimes, including the effects of single crystal anisotropy, texture and microstructure evolution. Synergetic studies, involving different crystal plasticity-based models, including multiscale implementations of the latter, and measurements of global and local textures, internal strains, dislocation structures, twinning, phase distribution, etc, were discussed in more than 90 presentations. The papers in this issue are representative of the different length-scales, materials, and experimental and

  19. Sindérese, o intellectus principiorum da razão prática segundo Tomás de Aquino = Synderesis, the intellectus principiorum of practical reason according to Thomas Aquinas

    Directory of Open Access Journals (Sweden)

    Abertuni, Carlos Alberto

    2011-01-01

    Full Text Available Trata-se de uma investigação sobre a teoria dos primeiros princípios da razão prática na obra de Tomás de Aquino. No centro dessa teoria está o termo “sindérese”, cujo conteúdo foi elaborado nas discussões da filosofia e da teologia medievais, a partir de sua menção na Glosa de Jerônimo a Ezequiel. Tal termo designa um conceito que apresenta um caráter inovador dentro da teoria da ação moral em comparação com a ética aristotélica. Afinal, Tomás de Aquino o entende como o hábito dos primeiros princípios da moral, equivalente ao hábito dos primeiros princípios teóricos de Aristóteles. Dessa forma, o interesse é compreender como o conceito de sindérese é recebido e desenvolvido na filosofia moral de Tomás de Aquino através da análise das três questões tradicionais: de sua natureza, de sua infalibilidade e de sua extinção

  20. Association of enteric parasitic infections with intestinal inflammation and permeability in asymptomatic infants of São Tomé Island.

    Science.gov (United States)

    Garzón, Marisol; Pereira-da-Silva, Luis; Seixas, Jorge; Papoila, Ana Luísa; Alves, Marta; Ferreira, Filipa; Reis, Ana

    2017-05-01

    The cumulative effect of repeated asymptomatic enteric infections on intestinal barrier is not fully understood in infants. We aimed to evaluate the association between previous enteric parasitic infections and intestinal inflammation and permeability at 24-months of age, in asymptomatic infants of São Tomé Island. A subset of infants from a birth cohort, with intestinal parasite evaluations in at least four points of assessment, was eligible. Intestinal inflammatory response and permeability were assessed using fecal S100A12 and alpha-1-antitrypsin (A1AT), respectively. The cutoff parasitic infections explained variability of fecal biomarkers, after adjusting for potential confounders. Eighty infants were included. Giardia duodenalis and soil-transmitted helminths (STH) were the most frequent parasites. The median (interquartile range) levels were 2.87 μg/g (2.41-3.92) for S100A12 and 165.1 μg/g (66.0-275.6) for A1AT. Weak evidence of association was found between S100A12 levels and G. duodenalis (p = 0.080) and STH infections (p = 0.089), and between A1AT levels and parasitic infection of any etiology (p = 0.089), at 24-months of age. Significant associations between A1AT levels and wasting (p = 0.006) and stunting (p = 0.044) were found. Previous parasitic infections were not associated with fecal biomarkers at 24 months of age. To summarize, previous asymptomatic parasitic infections showed no association with intestinal barrier dysfunction. Notwithstanding, a tendency toward increased levels of the inflammatory biomarker was observed for current G. duodenalis and STH infections, and increased levels of the permeability biomarker were significantly associated with stunting and wasting.

  1. Sci-Thur PM – Brachytherapy 02: Positional accuracy in Pd-103 permanent breast seed implant (PBSI) brachytherapy at the Tom Baker Cancer Centre (TBCC)

    Energy Technology Data Exchange (ETDEWEB)

    Frederick, Amy; Watt, Elizabeth; Peacock, Michael; Husain, Siraj; Meyer, Tyler; Roumeliotis, Michael [University of Calgary, Tom Baker Cancer Centre (Canada)

    2016-08-15

    Purpose: This retrospective study aims to quantify the positional accuracy of seed delivery in permanent breast seed implant (PBSI) brachytherapy at the Tom Baker Cancer Centre (TBCC). Methods: Treatment planning and post-implant CT scans for 5 patients were rigidly registered using the MIM Symphony™ software (MIM Software, Cleveland, OH) and used to evaluate differences between planned and implanted seed positions. Total and directional seed displacements were calculated for each patient in a clinically relevant ‘needle coordinate system’, defined relative to the angle of fiducial needle insertion. Results: The overall average total seed displacement was 10±8 mm. Systematic seed displacements were observed in individual patients and the magnitude and direction of these offsets varied among patients. One patient showed a significant directional seed displacement in the shallow-deep direction compared with the other four patients. With the exception of this one patient outlier, no significant systematic directional displacements in the needle coordinate system were observed for this cohort; the average directional displacements were −1±5 mm, 2±3 mm, and −2±4 mm in the shallow-deep, up-down, and right-left directions respectively. Conclusion: With the exception of one patient outlier, the magnitude of seed displacements were relatively consistent among patients. The results indicate that the shallow-deep direction possesses the largest uncertainty for the seed delivery method used at the TBCC. The relatively large uncertainty in seed placement in this direction is expected, as this is the direction of needle insertion. Further work will involve evaluating deflections of delivered needle tracks from their planned positions.

  2. Phenolic characterization and variability in leaves, stems and roots of Micro-Tom and patio tomatoes, in response to nitrogen limitation.

    Science.gov (United States)

    Larbat, Romain; Paris, Cédric; Le Bot, Jacques; Adamowicz, Stéphane

    2014-07-01

    Phenolics are implicated in the defence strategies of many plant species rendering their concentration increase of putative practical interest in the field of crop protection. Little attention has been given to the nature, concentration and distribution of phenolics within vegetative organs of tomato (Solanum lycopersicum. L) as compared to fruits. In this study, we extensively characterized the phenolics in leaves, stems and roots of nine tomato cultivars using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS(n)) and assessed the impact of low nitrogen (LN) availability on their accumulation. Thirty-one phenolics from the four sub-classes, hydroxycinnamoyl esters, flavonoids, anthocyanins and phenolamides were identified, five of which had not previously been reported in these tomato organs. A higher diversity and concentration of phenolics was found in leaves than in stems and roots. The qualitative distribution of these compounds between plant organs was similar for the nine cultivars with the exception of Micro-Tom because of its significantly higher phenolic concentrations in leaves and stems as compared to roots. With few exceptions, the influence of the LN treatment on the three organs of all cultivars was to increase the concentrations of hydroxycinnamoyl esters, flavonoids and anthocyanins and to decrease those of phenolamides. This impact of LN was greater in roots than in leaves and stems. Nitrogen nutrition thus appears as a means of modulating the concentration and composition of organ phenolics and their distribution within the whole plant. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  3. Sistema de Información para el proceso de acreditación de la Universidad Santo Tomás de Tunja

    Directory of Open Access Journals (Sweden)

    Ivan Fernando Fonseca Barinas

    2011-05-01

    Full Text Available El Sistema de Información para el Proceso de Acreditación de la Universidad Santo Tomás es el esfuerzo de muchas personas que colaboraron en el proyecto de forma permanente, no solo para plantear una solución a la administración de la información generada en el proceso de acreditación, sino también para involucrarse realmente en el mejoramiento continuo de cada facultad y con el compromiso de alcanzar la misión de la institución. El presente trabajo detalla cómo en la etapa de diseño se modeló la realidad del proceso de acreditación con la ayuda de diferentes diagramas: diagrama arquitectónico, diagrama entidad relación y el diagrama de clases que encapsula la lógica del negocio. Al concluir el diseño se inició la tarea de implementar el sistema, para esto se utilizó el patrón Modelo Vista Controlador. En el modelo se creó la base de datos con sus tablas y atributos, así como también se crearon las clases utilizando la arquitectura JEE. Para la vista se manejó el framework de ICEfaces buscando una interfaz amigable con componentes ricos que ayudan al usuario a trabajar fácilmente en la aplicación.

  4. Carbon isotope composition of intermediates of the starch-malate sequence and level of the crassulacean acid metabolism in leaves of Kalanchoe blossfeldiana Tom Thumb.

    Science.gov (United States)

    Deleens, E; Garnier-Dardart, J; Queiroz, O

    1979-09-01

    Isotype analyses were performed on biochemical fractions isolated from leaves of Kalanchoe blossfeldiana Tom Thumb. during aging under long days or short days. Irrespective of the age or photoperiodic conditions, the intermediates of the starch-malate sequence (starch, phosphorylated compounds and organic acids) have a level of (13)C higher than that of soluble sugars, cellulose and hemicellulose. In short days, the activity of the crassulacean acid metabolism pathway is predominant as compared to that of C3 pathway: leaves accumulate organic acids, rich in (13)C. In long days, the activity of the crassulacean acid metabolism pathway increases as the leaves age, remaining, however, relatively low as compared to that of C3 pathway: leaves accumulate soluble sugars, poor in (13)C. After photoperiodic change (long days→short days), isotopic modifications of starch and organic acids suggest evidence for a lag phase in the establishment of the crassulacean acid metabolism pathway specific to short days. The relative proportions of carbon from a C3-origin (RuBPC acitivity as strong discriminating step, isotope discrimination in vivo=20‰) or C4-origin (PEPC activity as weak discriminating step, isotope discrimination in vivo=4‰) present in the biochemical fractions were calculated from their δ(13)C values. Under long days, 30 to 70% versus 80 to 100% under short days, of the carbon of the intermediates linked to the starch-malate sequence, or CAM pathway (starch, phosphorylated compounds and organic acids), have a C4-origin. Products connected to the C3 pathway (free sugars, cellulose, hemicellulose) have 0 to 50% of their carbon, arising from reuptake of the C4 from malate, under long days versus 30 to 70% under short days.

  5. ʻWhere danger is, there rescue growsʼ: Technology, Time, and Dromology in Tom McCarthy’s C

    Directory of Open Access Journals (Sweden)

    Joakim Wrethed

    2017-12-01

    Full Text Available On one level, Tom McCarthy’s 'C' comes out as a postmodern intertextual patchwork that borrows the form of the 'Bildungsroman'. Accordingly, the protagonist Serge travels from birth to death in a forthrightly chronological narrative, but that journey is accompanied by the fact that the text’s modernist historical context is partly embedded in a posthuman and postmodern ontology. Technologically speaking, this version of modernity displays itself as 'technē', both in terms of artistic creation and as technology innovation (the radio transmitter, the car, the aeroplane, the cinema. Moreover, the novel equates technology with dromology (from Gr. 'dromos': race course dealing with increasing speed as economic and political advantage, but it also reveals its human downside in terms of disaster (war, car crash, aeroplane crash. Through the protagonist, C forwards technology as death drive and the human as always already being 'ahuman' ('technē' as primordial attribute of 'bios'. In terms of time, the narrative seemingly incarnates the occidental obsession with teleology and eschatology. This article goes through these dimensions, but in addition it contends that there is another level at work in the narrative. Considered as artistically rendered philosophical cognition, the novel puts forth the Stoic 'apathea' (equanimity, Husserlian flux, and anachronistic temporality as giving way to a peculiar kind of faith. This is closely tied to the artistic creativity of 'technē', including the activity of writing, which rescues a form of transcendence from conventional postmodern elimination. Dominant discourses of technology and time—apocalyptic and utopian—are challenged in this reading.

  6. Tom, Tom, the Piper's Son: Reading While Having Fun.

    Science.gov (United States)

    Holmes, Kerry

    2003-01-01

    This article describes how a first-grade teacher used poetry to provide students of diverse ability levels with reading and language activities that stimulated their interest and improved basic skills. Activities with poetry included reading the poems aloud individually and as a group, discussing and analyzing the poems' words and meanings, and…

  7. HYDRA Hyperspectral Data Research Application Tom Rink and Tom Whittaker

    Science.gov (United States)

    Rink, T.; Whittaker, T.

    2005-12-01

    HYDRA is a freely available, easy to install tool for visualization and analysis of large local or remote hyper/multi-spectral datasets. HYDRA is implemented on top of the open source VisAD Java library via Jython - the Java implementation of the user friendly Python programming language. VisAD provides data integration, through its generalized data model, user-display interaction and display rendering. Jython has an easy to read, concise, scripting-like, syntax which eases software development. HYDRA allows data sharing of large datasets through its support of the OpenDAP and OpenADDE server-client protocols. The users can explore and interrogate data, and subset in physical and/or spectral space to isolate key areas of interest for further analysis without having to download an entire dataset. It also has an extensible data input architecture to recognize new instruments and understand different local file formats, currently NetCDF and HDF4 are supported.

  8. ASK Talks with Tom Gavin

    Science.gov (United States)

    2004-01-01

    Thomas R. Gavin joined the Jet Propulsion Laboratory (JPL) in 1962. Currently the Associate Director of Flight Projects and Mission Success he has garnered a long list of engineering and management positions, including serving as mission assurance manager for both the Voyager and Galileo projects.

  9. Effect of the Absorbed Photosynthetically Active Radiation Estimation Error on Net Primary Production Estimation - A Study with MODIS FPAR and TOMS Ultraviolet Reflective Products

    International Nuclear Information System (INIS)

    Kobayashi, H.; Matsunaga, T.; Hoyano, A.

    2002-01-01

    Absorbed photosynthetically active radiation (APAR), which is defined as downward solar radiation in 400-700 nm absorbed by vegetation, is one of the significant variables for Net Primary Production (NPP) estimation from satellite data. Toward the reduction of the uncertainties in the global NPP estimation, it is necessary to clarify the APAR accuracy. In this paper, first we proposed the improved PAR estimation method based on Eck and Dye's method in which the ultraviolet (UV) reflectivity data derived from Total Ozone Mapping Spectrometer (TOMS) at the top of atmosphere were used for clouds transmittance estimation. The proposed method considered the variable effects of land surface UV reflectivity on the satellite-observed UV data. Monthly mean PAR comparisons between satellite-derived and ground-based data at various meteorological stations in Japan indicated that the improved PAR estimation method reduced the bias errors in the summer season. Assuming the relative error of the fraction of PAR (FPAR) derived from Moderate Resolution Imaging Spectroradiometer (MODIS) to be 10%, we estimated APAR relative errors to be 10-15%. Annual NPP is calculated using APAR derived from MODIS/ FPAR and the improved PAR estimation method. It is shown that random and bias errors of annual NPP in a 1 km resolution pixel are less than 4% and 6% respectively. The APAR bias errors due to the PAR bias errors also affect the estimated total NPP. We estimated the most probable total annual NPP in Japan by subtracting the bias PAR errors. It amounts about 248 MtC/yr. Using the improved PAR estimation method, and Eck and Dye's method, total annual NPP is 4% and 9% difference from most probable value respectively. The previous intercomparison study among using fifteen NPP models4) showed that global NPP estimations among NPP models are 44.4-66.3 GtC/yr (coefficient of variation = 14%). Hence we conclude that the NPP estimation uncertainty due to APAR estimation error is small

  10. [Mapping mini-implant anatomic sites in the area of the maxillary first molar with the aid of the NewTom 3G® system].

    Science.gov (United States)

    Dumitrache, Marius; Grenard, Annabelle

    2010-12-01

    The goal of our study was to construct a map of the implant sites in the region of the attached gingiva around the maxillary first molars that would be appropriate locations for placement of miniscrews to serve as orthodontic anchorage. We conducted 58 radiographic examinations with the NewTom 3G(®) cone beam technique. For each interdental space, between upper second bicuspids and first molars (5/6) and between upper first and second molars (6/7), we studied the mesio-distal width and depth of bucco-lingual bone at two different levels, L1 and L2, that corresponded to the lower and upper limits of the attached gingiva in the general population. The widths of the interdental spaces varied very little between L1 and L2 and their variances were comparable. At the level of the 5/6 space, the interdental widths displayed a Gaussian distribution, which made it possible for us to determine the confidence intervals at the two borders of attached gingiva as a function of age: IC(99%) of L1 = [2.045 ; 3.462] from 12 to 17 years or [1.594 ; 2.519] from 18 to 24 or [1.613 ; 2.5] from 25 to 48 years and IC(99%) of L2 = [2.37 ; 3.69] from 12 to 17 years or [1.5 ; 2.613] from 18 to 24 or [1.546 ; 2.619] from 25 to 48 ans. The interdental depths increased in an apical direction and their variance diminished. Even if the adequacy of the Gaussian law is less reliable in the sagittal plane, we find a greater consistency in depths in the spaces around 5/6 that allows us to establish very precise confidence levels: IC(99%) of L1 = [9.213; 10.575] and IC(99%) of L2 = [10.295; 11.593]. The mesial areas of the first molars constitute safe zones for implantation of miniscrews with a maximum of 2-2.3 mm for 12 to 17 years old or 1.5-1.6 mm for 18 to 48 year olds and of a maximum of 9-10 mm in length whether the attached gingival level is strong or feeble. The distal areas of the first molars, because of their great variability, require an individualized radiographic study before any mini

  11. La historia blanqueada: representaciones de los africanos y sus descendientes en Antioquia a través de la obra de Tomás Carrasquilla

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    Lina del Mar Moreno Tovar

    2010-06-01

    Antioquia y a sus habitantes como correlato exitoso de la asociación entre raza blanca y montañas andinas, en contraste con valoraciones negativas sobre las tierras bajas y pobladores negros. El artículo busca por una parte examinar cuáles fueron los mecanismos de representación de los africanos y sus descendientes en Antioquia, mediante el análisis de la obra literaria de Tomás Carrasquilla y, por otra, evidenciar que esas elaboraciones marginaron los aportes de los africanos y sus descendientes a la historia antioqueña.

  12. Estrutura do componente arbóreo em áreas de cerrado no município de São Tomé das Letras, MG

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    Renata de Melo Ferreira Lopes

    2013-10-01

    Full Text Available O município de São Tomé das Letras localiza-se ao sul de Minas Gerais, na bacia do rio Grande, em área de transição entre a Floresta Atlântica e o Cerrado, onde se distinguem também campos rupestres. Possui economia baseada em extrativismo mineral, agropecuária e turismo. Este trabalho teve como objetivo determinar a estrutura fitossociológica de três áreas de cerrado no município. Foram amostrados 60 pontos-quadrantes por área, tomando-se medidas de altura das árvores e circunferência de tronco (≥ 10 cm à altura do solo. Foram calculados para cada ambiente: densidade de indivíduos, dominância, frequência, área basal, Valor de Importância (VI e diversidade florística (Índice de Shannon, H'. Ao todo, foram identificadas 27 famílias, 36 gêneros e 56 espécies. Eremanthus erythropappus (candeia, Asteraceae foi a espécie de maior Valor de Importância (VI encontrada nas áreas Candeias e Vale das Borboletas e Stryphnodendron adstringens (barbatimão, Fabaceae e Piptocarpha rotundifolia (coração-de-negro, Asteraceae as espécies que se destacaram em VI na área Carrapatos. A altura média variou de 2,0 ± 1,2 a 2,3 ± 1,3m. O diâmetro médio variou de 6,5 ± 4,4 a 7,3 ± 4,8 cm. A densidade média foi de 2315 indiv.ha-1 e área basal média de 13,4 m².ha-1. O índice de diversidade de Shannon (H' para espécies variou de 2,67 a 2,96 nats/ind. Foi observada baixa similaridade de espécies entre as três áreas. Considerando as pressões antrópicas que os ambientes naturais da região vêm sofrendo, os dados obtidos poderão subsidiar projetos locais de recomposição da vegetação, principalmente do componente arbóreo.

  13. Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi and other intestinal parasites in young children in Lobata province, Democratic Republic of São Tomé and Principe.

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    Maria Luísa Lobo

    Full Text Available Rare systemic studies concerning prevalence of intestinal parasites in children have been conducted in the second smallest country in Africa, the Democratic Republic of São Tomé and Príncipe. Fecal specimens from 348 children (214 in-hospital attending the Aires de Menezes Hospital and 134 from Agostinho Neto village in São Tome Island were studied by parasitological and molecular methods. Of the 134 children from Agostinho Neto, 52.2% presented intestinal parasites. 32.1% and 20.2% of these children had monoparasitism and polyparasitism, respectively. Ascaris lumbricoides (27.6%, G. duodenalis (7.5%, T. trichiura (4.5% and Entamoeba coli (10.5% were the more frequent species identified in the children of this village. Giardia duodenalis (7.5% and E. bieneusi (5.2% were identified by PCR. Nested-PCR targeting G. duodenalis TPI identified Assemblage A (60% and Assemblage B (40%. The E. bieneusi ITS-based sequence identified genotypes K (57.1%, KIN1 (28.6% and KIN3 (14.3%. Among the 214 in-hospital children, 29.4% presented intestinal parasites. In 22.4% and 7.0% of the parasitized children, respectively, one or more species were concurrently detected. By microscopy, A. lumbricoides (10.3% and Trichiuris trichiura (6.5% were the most prevalent species among these children, and Cryptosporidium was detected by PCR in 8.9% of children. GP60 locus analysis identified 6.5% of C. hominis (subtypes IaA27R3 [35.7%], IaA23R3 [14.3%], IeA11G3T3 [28.6%] and IeA11G3T3R1 [21.4%] and 2.3% of C. parvum (subtypes IIaA16G2R1 [20.0%], IIaA15G2R1 [20.0%], IIdA26G1 [40.0%] and IIdA21G1a [20.0%]. G. duodenalis and E. bieneusi were identified in 0.5% and 8.9% of the in-hospital children, respectively. G. duodenalis Assemblage B was characterized. The E. bieneusi genotypes K (52.6%, D (26.4%, A (10.5% and KIN1 (10.5% were identified. Although further studies are required to clarify the epidemiology of these infectious diseases in this endemic region the significance

  14. Application of loop-mediated isothermal amplification for malaria diagnosis during a follow-up study in São Tomé.

    Science.gov (United States)

    Lee, Pei-Wen; Ji, Dar-Der; Liu, Chia-Tai; Rampao, Herodes S; do Rosario, Virgilio E; Lin, I-Feng; Shaio, Men-Fang

    2012-12-06

    A reliable and simple test for the detection of malaria parasite is crucial in providing effective treatment and therapeutic follow-up, especially in malaria elimination programmes. A comparison of four methods, including nested polymerase chain reaction (PCR) and loop-mediated isothermal amplification (LAMP) were used for the malaria diagnosis and treatment follow-up in São Tomé and Príncipe, during a successful pre-elimination campaign. During the period September to November 2009, blood samples from 128 children (five to 14 years old) with temperature ≥38°C (tympanic) in the District of Agua Grande were examined using four different methods, i.e., histidine-rich protein 2 (HRP-2) based rapid diagnostic tests (HRP-2-RDTs), optical microscopy, nested PCR, and LAMP. First-line treatment with artesunate-amodiaquine was given for uncomplicated malaria and intravenous quinine was given for complicated malaria. Children with persistent positivity for malaria by microscopy, or either by nested PCR, or by LAMP on day 7 were given second-line treatment with artemether-lumefantrine. Treatment follow-up was made weekly, for up to four weeks. On day 0, positive results for HRP-2-RDTs, microscopy, nested PCR, and LAMP, were 68(53%), 47(37%), 64(50%), and 65(51%), respectively. When nested PCR was used as a reference standard, only LAMP was comparable; both HRP-2-RDTs and microscopy had moderate sensitivity; HRP-2-RDTs had poor positive predictive value (PPV) and a moderate negative predictive value (NPV) for the treatment follow-up. Seventy-one children with uncomplicated malaria and eight children with complicated falciparum malaria were diagnosed based on at least one positive result from the four tests as well as clinical criteria. Twelve of the 79 children receiving first-line treatment had positive results by nested PCR on day 7 (nested PCR-corrected day 7 cure rate was 85%). After the second-line treatment, nested PCR/LAMP-corrected day 28 cure rate was 83% for

  15. Cobalt(II Complexes with N,N,N-Scorpionates and Bidentate Ligands: Comparison of Hydrotris(3,5-dimethylpyrazol-1-ylborate Tp* vs. Phenyltris(4,4-dimethyloxazolin-2-ylborate ToM to Control the Structural Properties and Reactivities of Cobalt Centers

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    Toshiki Nishiura

    2018-06-01

    Full Text Available Scorpionate ligands Tp* (hydrotris(3,5-dimethylpyrazol-1-ylborate and ToM (tris(4,4-dimethyloxazolin-2-ylphenylborate complexes of cobalt(II with bidentate ligands were synthesized. Both Tp* and ToM coordinate to cobalt(II in a tridentate fashion when the bidentate ligand is the less hindered acetylacetonate. In crystal structures, the geometry of cobalt(II supported by the N3O2 donor set in the Tp* complex is a square-pyramid, whereas that in the ToM complex is close to a trigonal-bipyramid. Both Tp*- and ToM-acac complexes exhibit solvatochromic behavior, although the changing structural equilibria of these complexes in MeCN are quite different. In the bis(1-methylimidazol-2-ylmethylphenylborate (LPh complexes, Tp* retains the tridentate (к3 mode, whereas ToM functions as the bidentate (к2 ligand, giving the tetrahedral cobalt(II complex. The bowl-shaped cavity derived from the six methyl groups on ToM lead to susceptibility to the bulkiness of the opposite bidentate ligand. The entitled scorpionate compounds mediate hydrocarbon oxidation with organic peroxides. Allylic oxidation of cyclohexene occurs mainly on the reaction with tert-butyl hydroperoxide (TBHP, although the catalytic efficiency of the scorpionate ligand complexes is lower than that of Co(OAc2 and Co(acac2. On cyclohexane oxidation with meta-chloroperbenzoic acid (mCPBA, both ToM and Tp* complexes function as catalysts for hydroxylation. The higher electron-donating ToM complexes show faster initial reaction rates compared to the corresponding Tp* complexes.

  16. Os sentidos de theologia physica para os antiqui: Tomás de Aquino leitor de Agostinho [The senses of theologia physica for the antiqui: Thomas Aquinas reads Augustine

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    Evaniel Brás dos Santos

    2017-05-01

    Full Text Available Explicito neste artigo que a expressão “theologia physica” atribuída aos antigos (antiqui possui dois sentidos na ST, IIa-IIae, q. 94, a. 1, resp., de Tomás de Aquino. O primeiro, atribuído a Varrão, denota um estudo restrito, uma physiologia ou mecânica na qual deus é entendido como a força imanente no mundo, locomovendo-o. O segundo, por sua vez, pertence aos platônicos (platonici e denota um estudo geral, pois aborda, além de entidades imateriais, um criador. Ambas as teologias físicas, conforme Tomás, institui filosoficamente a idolatria ao entenderem que a divindade é causa de locomoção. Embora se valha de Agostinho em sua leitura da expressão “theologia physica”, Tomás introduz discussões que estão além do texto agostiniano.  [In the article I clarify that the expression “theologia physica” attributed to the Ancients (antiqui has two senses in the ST, IIa-IIae, q. 94, a.1, resp., of Thomas Aquinas. The first, attributed to Varro, denotes a restrict study, a physiologia or mechanics in which god is understood as the immanent force in the world, moving it. The second, in turn, belongs to the Platonics (platonici and denotes a general study, for it approaches, besides immaterial entities, a creator. Both physical theologies, according to Aquinas, set up philosophically the idolatry since they understand that the divinity is cause for locomotion. Although Aquinas makes use of Augustine in his reading of the expression “theologia physica”, he introduces discussions that go beyond the Augustinian text.

  17. Basal testosterone concentrations after the application of a slow-release GnRH agonist implant are associated with a loss of response to buserelin, a short-term GnRH agonist, in the tom cat.

    Science.gov (United States)

    Goericke-Pesch, Sandra; Georgiev, Plamen; Fasulkov, Ivan; Vodenicharov, Angel; Wehrend, Axel

    2013-07-01

    Slow-release GnRH agonist implants are considered an effective, reversible alternative to surgical castration in male tom cats. Individual differences exist regarding the onset of efficacy and might be delayed in some animals. Single measurements of testosterone (T) might result in basal concentrations also in intact male cats. Consequently, GnRH stimulation tests are performed to measure T increase in intact animals and to differentiate castrated from intact male cats. In this study, five tom cats were treated with a 4.7-mg deslorelin implant and GnRH stimulation tests using buserelin were performed before treatment and at 4-week intervals afterward until Week 20. After the last test in Week 20 all animals were castrated. Four of five animals had basal T after 4 weeks and-in contrast to pretreatment-application of buserelin did not result in any further T increase. In one animal, T was low after implant insertion, but not basal; however, a GnRH stimulation test induced a slight increase of T in Week 8 and 16 only and no response in Weeks 4, 12, and 20. Testicular volume was significantly decreased and penile spines disappeared in all cats. Testicular histology showed mixed atrophy, but also fully elongated spermatids in three of five male cats making infertility questionable. Because of the loss of the stimulatory effect of short-term GnRH application (buserelin), it can be assumed that long-term GnRH agonists also act by some mechanisms of downregulation of pituitary GnRH receptors in the tom cat. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. (ReConstrução Mítica de Eva Perón no Romance Santa Evita (1996 – Tomás Eloy Martínez

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    Josiane Valcarenghi Ribeiro Nantes

    2017-06-01

    Full Text Available Eva Perón é um nome significativo na história política da Argentina, sua influência surtiu, e continua surtindo efeito, no povo desse país até os dias atuais. “Evita” foi odiada/amada em níveis extremos, tanto que foi considerada uma santa, um mito para muitas pessoas. Tomás Eloy Martínez escreveu o romance – Santa Evita (1995 – em que narra como viveu a esposa de Juan Domingo Perón. Nesta obra encontra-se muitos elementos que dão indícios da (remitificação de Eva, por isso tenta-se aqui, explorar como se deu a (reconstrução mitológica de Eva Perón, personagem histórica no romance Santa Evita (1996 de Tomás Eloy Martínez, e ainda, expor quais foram os procedimentos adotados pelo autor que (reconstruíram esse mito. Utiliza-se, como base teórica, Linda Hutcheon (1991 e Fleck (2007 no conceito de metaficção historiográfica, Mircea Eliade (1991 e Martín Cezar Feijó (1984 no que cabe à análise do Mito. Esta breve pesquisa se dará a partir da análise bibliográfica e de forma comparativa entre a história e a escrita ficcional do romance Santa Evita (1996 de Tomás Eloy Martínez, discute-se os elementos utilizados e o caminho percorrido para a (reconstrução do mito Eva Perón na obra citada.

  19. Fatores associados à adequação do cuidado pré-natal e à assistência ao parto em São Tomé e Príncipe, 2008-2009

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    Patrícia Alexandra da Graça Dantas dos Reis

    2015-09-01

    Full Text Available Neste artigo, foram identificados fatores sociodemográficos associados com o cuidado pré-natal e com a assistência ao parto em São Tomé e Príncipe. A amostra foi composta por 1.326 nascidos vivos de mulheres de 15 a 49 anos que participaram do Inquérito Demográfico e Sanitário de São Tomé e Príncipe, 2008-2009. Foram utilizados modelos de regressão logística e multinomial multiníveis. A adequação global do cuidado pré-natal foi de 26% e da assistência ao parto de 7% quando realizado por médicos e de 76% quando realizado por enfermeiras/auxiliares. Os fatores associados ao pré-natal e à assistência ao parto adequados foram: ordem de nascimento, educação materna e o índice de bem-estar econômico. O local de residência se mostrou fator importante apenas em relação à assistência ao parto. Observou-se que os efeitos aleatórios referentes às áreas onde as mulheres residem exerceram impacto importante sobre a chance de realizar pré-natal adequado e parto com profissionais capacitados. A importância dos fatores socioeconômicos aponta para a elaboração de ações que visem reduzir a desigualdade social em São Tomé e Príncipe.

  20. Os inconfidentes nas Minas Gerais: uma relação entre a Geografia e a Literatura Setecentista de Cláudio Manuel da Costa, Tomás Antônio Gonzaga e Alvarenga Peixoto

    OpenAIRE

    Araújo, Kárita de Fátima

    2014-01-01

    Objetivando compreender a maneira pela qual se processou a construção da identidade nacional e da formação territorial brasileira no contexto das Minas Gerais setecentistas, procuramos fazê-lo à luz das obras literárias dos poetas inconfidentes. Para tal, escolhemos Vila Rica de Cláudio Manuel da Costa; Cartas chilenas de Tomás Antônio Gonzaga e, Canto Genetlíaco de Inácio José de Alvarenga Peixoto. Ao trabalhar no entrecruzamento da Geografia com a Literatura, buscamos aliar a...

  1. Biogeochemical migration of heavy metals, Ti, V, Mo, Ta, W, and U, in the profile of a low-laid peatbog in the country between the Ob and Tom rivers

    International Nuclear Information System (INIS)

    Efremova, T.T.; Efremov, S.P.; Koutsenogii, K.P.; Peresedov, V.F.

    2003-01-01

    Biogeochemical migration of heavy metals in the course of marsh formation is mainly determined by physical-chemical processes, such as the oxidation-reduction zonality of the peatbog thickness and the state of humous substances (the quality of humus adsorptive barriers). In the process of peatbog formation V, U, Ta are the weakly captured elements while Mo is captured to a relatively higher extent. Elements as Ti and W are found in separate layers. No technogenic degradation of the marsh ecosystem in the Ob and Tom has been observed. (author)

  2. Interakce mediálního a marketingového diskurzu na příkladu mediálního obrazu hudebníka Tomáše Kluse

    OpenAIRE

    Nováková, Kristýna

    2011-01-01

    This diploma thesis Interaction of media and marketing discourse on the media image of musician Tomáš Klus examines the influence of the corporate agenda through the marketing and PR department of a record label Sony Music Entertainment Czech Republic s.r.o. on the agenda of the media, which represent the work of three full-scale Czech newspaper MF Dnes, Právo a Blesk. The theoretical approach is being built on the basic theses of media construction of reality and construction of media image,...

  3. L’Epítome de Llorenç Tomàs, canceller del Principat de Catalunya (1705-1714). Un document fins ara desconegut sobre els precedents de la Guerra de Successió

    OpenAIRE

    Ballbé i Sans, Neus

    2006-01-01

    Estudi centrat en l’epítom escrit pel canceller de Catalunya durant el govern de Carles III i que explica, en primera persona, els fets esdevinguts a la plana de Vic abans de l’arribada de l’Arxiduc el 1705. Estudio centrado en el epítome escrito por el canciller de Cataluña durante el gobierno de Carlos III y que explica, en primera persona, los hechos ocurridos en el llano de Vic antes de la llegada del Archiduque en 1705. Study centered on the written epitome by the chancellor of Cat...

  4. Enfermedad de Tomás en el sector salud pinareño Tomas's disease in Pinar del Rio health sector

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    Lidia Rosa Salgueiro Labrador

    2012-10-01

    Full Text Available Introducción: médicos, pacientes y sociedad precisan del desarrollo armónico de una ética contemporánea que responda a las exigencias de las nuevas relaciones que el desarrollo científico-técnico y cultural impone, al influjo de las profundas transformaciones socioeconómicas y políticas a que el presente siglo reta. Objetivo: determinar la influencia de la Enfermedad de Tomás o síndrome de Burn-out en cinco policlínicos y dos clínicas estomatológicas de Pinar del Río y Consolación del Sur en el mes de marzo del año 2011. Material y Método: se realizó una investigación descriptiva, en opinión de 234 profesionales encuestados y aplicó una encuesta compuesta de cinco preguntas con cinco opciones para seleccionar la más aceptable. Los resultados se procesaron por la estadística descriptiva determinando frecuencias absolutas y relativas que se presentan en tablas. Resultados: el estudio constató que las respuestas relacionan los problemas actuales, a la crisis de valores entre los profesionales, en un 64,5% de las respuestas; más del 50% opinan que la crisis es evitable en parte, recomiendan mejorar condiciones salariales para reforzar motivaciones, en más de las tres quintas partes y el 32% consideran que debe mejorar la formación humanista y perfeccionar la organización de los servicios. El 45,7% considera que la relación usuario-paciente-institución tiene imperfecciones en su organización y recomiendan prestar más atención a la discusión colectiva de los problemas e incentivar el reforzamiento de valores entre los trabajadores del sector, sumando más del 70% las respuestas. Conclusiones: a pesar de que se percibe la desmotivación que caracteriza la enfermedad de Tomás, el mal es prevenible por la confianza en los profesionales y la voluntad política que orienta el trabajo en salud hacia la excelencia.Introduction: medical doctors, patients and society require the harmonic development of a contemporaneous

  5. The Song of the Sabia in the 3rd. Festival Internacional da Canção: boo and sunset of the Tom Jobim bossa nova`s aesthetics

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    Fabio Guilherme Poletto

    2015-07-01

    Full Text Available This article discusses the Song of the Sabia, composition of Tom Jobim and Chico Buarque. Mobilizes different series of sources in order to reconstruct historically the boo to the performance of the song during the III International Song Festival, held in 1968 in the city of Rio de Janeiro. Seeks to highlight how this episode catalyzed the existence of different expectations on the popular song and its role as a vehicle for ideals of modernity amid the interference of the authoritarian environment in the cultural and political field. Then, based on the analysis of the constitutive parameters of the song, suggests possibilities for understanding its musical and poetic construction in critical dialogue with its reverberations in cultural terms.This article discusses the Song of the Sabia, composition of Tom Jobim and Chico Buarque. Mobilizes different series of sources in order to reconstruct historically the boo to the performance of the song during the III International Song Festival, held in 1968 in the city of Rio de Janeiro. Seeks to highlight how this episode catalyzed the existence of different expectations on the popular song and its role as a vehicle for ideals of modernity amid the interference of the authoritarian environment in the cultural and political field. Then, based on the analysis of the constitutive parameters of the song, suggests possibilities for understanding its musical and poetic construction in critical dialogue with its reverberations in cultural terms.

  6. 'A mate or a meal' – Pre-gravid behaviour of female Anopheles gambiae from the islands of São Tomé and Príncipe, West Africa

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    Ferreira Conceicao

    2003-05-01

    Full Text Available Abstract Background Malaria prevalence differs between the two islands that comprise the archipelago of São Tomé and Príncipe. This may be due to differences in the biology of local Anopheles gambiae, the only vector on the islands. Survival rate and feeding frequency are two factors influencing vectorial capacity. Anophelines generally feed just once per gonotrophic (oviposition cycle. Newly emerged insects, however, may feed two or more times during their first oviposition cycle thus increasing the likelihood of becoming infected. The reasons for multiple feeding are not clearly understood and it is still uncertain whether the behaviour is facultative or obligatory. We, therefore, determined survival and sporozoite rates, and examined the behaviour of An. gambiae from the two islands during their first gonotrophic cycle. Methods The wing size of 1,410, abdominal condition of 687, gonotrophic age and mated status of 7,264 female M form An. gambiae collected by light-trap, landing catch, resting outdoors or in copula, was determined from four sites in the archipelago. Sporozoite rates assessed by ELISA in 15,533 females from São Tomé and 2,111 from Príncipe were determined. Results Estimated survival rates ranged between 0.834–0.849 per day in São Tomé and 0.801–0.818 per day in Príncipe. Sporozoite rates of 0.63% in São Tomé were significantly higher than the 0.24% from Príncipe. Overall 49% of females mated on the second night after emergence before feeding, and 51% on the third night and thus fed before mating. The likelihood of mating before feeding increased with wing size. None of the 3,776 parous insects collected showed evidence of recent mating. All but two of the 198 females collected in copula had undeveloped ovaries. Mean wing sizes and the number of insects collected in a sentinel light-trap varied but the proportion of newly emerged insects in the collection did not. The estimated survival rate of the smallest

  7. 5-7 Year Old Children's Conceptions of Behaving Artifacts and the Influence of Constructing Their Behavior on the Development of Theory of Mind (ToM and Theory of Artificial Mind (ToAM

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    Karen Spektor-Precel

    2015-12-01

    Full Text Available Nowadays, we are surrounded by artifacts that are capable of adaptive behavior, such as electric pots, boiler timers, automatic doors, and robots. The literature concerning human beings’ conceptions of “traditional” artifacts is vast, however, little is known about our conceptions of behaving artifacts, nor of the influence of the interaction with such artifacts on cognitive development, especially among children. Since these artifacts are provided with an artificial “mind,” it is of interest to assess whether and how children develop a Theory of Artificial Mind (ToAM which is distinct from their Theory of Mind (ToM. The study examined a new theoretical scheme named ToAM (Theory of Artificial Mind by means of qualitative and quantitative methodology among twenty four 5-7 year old children from central Israel. It also examined the effects of interacting with behaving artifacts (constructing versus observing the robot’s behavior using the “RoboGan” interface on children’s development of ToAM and their ToM and looked for conceptions that evolve among children while interacting with behaving artifacts which are indicative of the acquisition of ToAM. In the quantitative analysis it was found that the interaction with behaving artifacts, whether as observers or constructors and for both age groups, brought into awareness children’s ToM as well as influenced their ability to understand that robots can behave independently and based on external and environmental conditions. In the qualitative analysis it was found that participating in the intervention influenced the children’s ToAM for both constructors and for the younger observer. Engaging in building the robot’s behavior influenced the children’s ability to explain several of the robots’ behaviors, their understanding of the robot’s script-based behavior and rule-based behavior and the children’s metacognitive development. The theoretical and practical importance of

  8. A cidade africana contemporânea de origem portuguesa: São Tomé pré e pós-independência The contemporary African city of Portuguese origin: Sao Tome pre and post-independence

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    Teresa Madeira da Silva

    2012-12-01

    Full Text Available A cidade de São Tomé foi território português desde as primeiras ocupações até 1975 (data de sua independência,tendo, nesse tempo, crescido segundo os princípios do urbanismo de origem portuguesa. Para além da cidade planeada e consolidada, construída no período de ocupação colonial, a cidade desenvolveu, sobretudo no período pós-independência, um outro tipo de estrutura sem planeamento. À semelhança de outras cidades africanas de origem portuguesa, essa nova estrutura localiza-se na periferia do centro urbano. Este artigo apresenta dois argumentos. O primeiro considera que a cidade de São Tomé apresenta uma estrutura dual, tal como outras cidades africanas: uma zona central planeada, construída no período da ocupação colonial (pré-independência, e outra, periurbana, constituída essencialmente por habitações resultantes da expansão habitacional do centro urbano e com certas características semirrurais: vivendas associadas a espaços de produção agrícola familiar. O segundo argumento refere que tanto a estrutura central planeada, desenvolvida no período colonial, como a estrutura periférica não planeada, desenvolvida posteriormente,têm, na sua origem e desenvolvimento, a procura de relações com o território e, tanto numa como noutra,reconhecem-se estruturas urbanas adaptadas às condições locais.

  9. Presentación clínica de tuberculosis en pacientes VIH+ atendidos en el Hospital Santo Tomás, Panamá. Enero a julio del 2009

    Directory of Open Access Journals (Sweden)

    Bernardino Denis

    2010-01-01

    Full Text Available Objetivo: describir las presentaciones clínicas de la tuberculosis en los pacientes VIH+ atendidos en el Hospital Santo Tomás de enero a julio de 2009. Metodología: se trata de un estudio descriptivo retrospectivo que consistió en la revisión de expedientes clínicos de los pacientes que presentaron coinfección de tuberculosis y VIH en el Hospital Santo Tomás durante el primer semestre del año 2009. Se analizó el universo de pacientes. Se utilizó un formulario para la recolección de los datos y para el análisis de los datos se calcularon frecuencias, modas, medianas y promedios. Se utilizo el programa EpiInfo 3.5.1 y se realizaron los gráficos con Microsoft Office Excel. Resultados: La relación hombres : mujeres fue de 3 : 1. Se observó una mayor frecuencia de pacientes procedentes del corregimiento de Juan Díaz (13,5% Calidonia (10,4% Santa Ana (10,4%. La presentación clínica predominante fue la pulmonar (64,4% seguida por la mixta (20% y la extrapulmonar (15,6%; entre las formas extrapulmonares la más frecuente fue la ganglionar (37,5%. Conclusiones: La presentación clínica pulmonar reporta es de 64,4%; extrapulmonar, 15,6%; y mixta, 20,0%. Entre las presentaciones extrapulmonares, la presentación ganglionar se reporta en 37,5%. El método clínico radiológico es el medio diagnóstico más usado (76% a diferencia de otros estudios.

  10. Nota sobre a variação sazonal da circulação geostrófica na borda da plataforma continental: Cabo de São Tomé (RJ e a Baía de Guanabara (RJ Seasonal variation of geostrophic circulation on the continental slope: Cape of São Tomé (RJ and Guanabara Bay (RJ

    Directory of Open Access Journals (Sweden)

    Ademildes Maria Paviglione

    1985-01-01

    Full Text Available Cinco observações oceanográficas espaciais quase sinóticas, realizadas de janeiro de 1970 a fevereiro de 1971, na região entre o Cabo de São Tomé e a Baía de Guanabara, são usadas para descrever a circulação sazonal e as condições de fluxo da Corrente do Brasil próximo à plataforma continental. As velocidades relativas foram calculadas sobre superfícies isanostéricas, de acordo com o método sugerido por Montgomery (1937. A precisão do método foi analisada, com base na propagação dos erros instrumentais das medidas da temperatura, da salinidade e da profundidade sobre o volume específico e a aceleração potencial, obtendo-se uma precisão de cerca de ± 3,0 cm s-1, para a velocidade relativa, e um máximo de ± 2,5 Sv, para o transporte de volume através da secção transversal. As correntes geostróficas de superfície, calculadas com referência à superfície isanostérica de 100 cl ton-1, sao geralmente mais intensas através das secções a leste de Cabo Frio, onde elas atingem valores máximos (~90 cm s-1 na borda da plataforma continental durante o verão, e valores acima de 86 cm s-1 ocorrem no inverno, mais além, a distâncias da costa maiores do que 140 km. Os diagramas T-S mostram os detalhes da distribuição do fluxo nas classes características e o fato de que 50% do transporte total corresponde à Massa de Água Tropical, próxima da superfície isanostérica de 220 cl ton-1. As variações do transporte total na coluna de água, desde a superfície até a superfície isanostérica de referência, foram analisadas para estimar o transporte por unidade de largura.Five-nearly-synoptic spatial oceanographic observations, taken from January, 1970 to February, 1971, in the region between Cape of São Tomé and Guanabara Bay, are used to describe the seasonal circulation and flow conditions of the Brazil Current, close to the continental slope. The relative geostrophic velocities were calculated over isanosteric

  11. Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

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    Seán Gerard Brosnahan

    2014-11-01

    Full Text Available Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

  12. Acute and chronic malnutrition and their predictors in children aged 0-5 years in São Tomé: a cross-sectional, population-based study.

    Science.gov (United States)

    Valente, A; Silva, D; Neves, E; Almeida, F; Cruz, J L; Dias, C C; da Costa-Pereira, A; Caldas-Afonso, A; Guerra, A

    2016-11-01

    Undernutrition is an important cause of morbidity and mortality in infants and children worldwide. The aim of this study was to evaluate the nutritional status and their predictors in children from 0 to 5 years of age in São Tomé. A cross-sectional study was conducted in São Tomé Island. A total of 1285 individuals were enrolled between January and May 2011. Children were measured, and height for age (HAZ), weight for height (WHZ) and body mass index (BAZ) Z-score were computed. Global acute undernutrition is defined as weight for height health bulletins, namely gestational age and birth weight, as well as weight at 6, 12, 18 and 24 months for all individual above these ages. Mothers were invited to answer a specific questionnaire. A high percentage of global acute undernutrition (30.9% in 12 months. Weight gain above 0.67 Z-score in the first semester of life was strongly related to lower odds for both acute (OR 0.109 [95% CI 0.040-0.291]) and chronic undernutrition (OR 0.379 [95% CI 0.187-0.770]) in children >12 months of age. Similarly, mother's education seems to protect against acute (>12 months: OR 0.448 [95% CI 0.244-0.825]; >24 months: OR 0.186 [95% CI 0.064-0.540]) and chronic undernutrition (>12 months: OR 0.389 [95% CI 0.232-0.653]; >24 months: OR 0.324 [95% CI 0.171-0.625]). All logistic regressions were adjusted for all children (gender, age, gestational age, birth weight, breastfeeding, begin consumption alcohol), mothers (age, height, body mass index, educational level, number of previous pregnancies, smoking during pregnancy, alcohol consumption during pregnancy) and household (number of siblings and persons at home) variables included in the protocol. Birth weight, nutritional status, and the mother's education and weight gain particularly in the first year of life were important factors protecting against undernutrition during infancy and childhood. These results emphasize the importance of women's nutrition and of adequate birth weight and

  13. Arquitectura, urbanismo y obras públicas civiles y militares en el Atlas Geográfico de España de Tomás López de 1804

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    San-Antonio-Gómez, C.

    2016-06-01

    Full Text Available This manuscript presents a novel analysis that deals about how architecture, urban planning and civil and military public works are represented in Geographic Atlas of Spain 1804 (AGE of Tomas Lopez. For this it has been characterized different map symbols appearing on maps, which are the benchmarks for analysis and transmit accurate information on the shape and meaning of what is represented. So, more than one hundred different symbols were found. This gives an idea of the great detail and richness of the information contained in AGE. A deeper analysis shows that eighteen of them are equivalent to other previous cartographic symbols. These were from Chevalier, D’Anville teacher, who in turn was the teacher Thomas Lopez in Paris. Additionally, we found that there are several symbols with similarity to their corresponding of the Ordinances of the Royal Corps of Engineers from 1803.El objetivo que planteamos es analizar cómo Tomás López representó en su Atlas Geográfico de España (AGE de 1804, la arquitectura, el urbanismo y las obras públicas civiles y militares, un análisis hasta el momento inédito. Para ello se han caracterizado los diferentes símbolos cartográficos que aparecen en los mapas, que constituyen los parámetros de referencia del análisis y transmiten información fidedigna de la forma y significado de lo representado. Para esas tipologías se han encontrado ciento trece símbolos diferentes, lo que da idea de la minuciosidad y riqueza de la información contenida en los mapas. Dieciocho de ellos, son equivalentes con otros tantos símbolos cartográficos de Chevalier, maestro de D’Anville, de quien Tomás López fue discípulo en París. También hay una similitud entre cuatro símbolos del AGE con sus correspondientes signos de las Ordenanzas del Real Cuerpo de Ingenieros de 1803.

  14. Contribuição ao estudo da circulação e do transporte de volume da corrente do Brasil entre o Cabo de São Tomé e a Baía de Guanabara Contribution to the studies of transport and circulation of the Brazil current in the are a between Cabo de São Tomé and Guanabara Bay

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    Sérgio R Signorini

    1976-01-01

    Full Text Available Tal estudo teve por finalidade avaliar a velocidade e o transporte de volume da Corrente do Brasil, no seu trecho entre Cabo de São Tomé e Cabo Frio, fazendo uso do calculo geostrofico aplicado às secções amostradas durante os cruzeiros de abril e julho de 1970 e de julho de 1973. Foram localizados dois vórtices anticiclônicos, um durante o período de abril de 1970 e o outro durante julho de 1973. O valor máximo de velocidade da corrente na superfície foi de aproximadamente 70 cm/s e o transporte de volume foi de 14 x 10(6 m³/s. Foi possível também confirmar a existência de um meandro da Corrente do Brasil através da utilização de uma secção de BT (batitermografo mecânico associada a um registro contínuo de salinidade e de temperatura obtido com um termosalinografo.During the periods of April, July, 1970 and July, 1973, océanographic cruises were conducted in order to investigate the variability of the Brazil Current in the region between Cabo de Sao Tomé and Guanabara Bay. The geostrophic model of ocean circulation was applied using the hydrographie data collected during the cruise. From this study, a maximum velocity of 70 cm/sec and a volume trans port of 14 x 10(6 m³/sec were reported. The dynamic topography with reference to the 500 db surface, showed the presence of anticyclonic eddies during the periods of April, 1970, and July, 1973. The thermohaline structure within a meander of the Brazil Current is also presented utilizing the data coming from a continuous salinity and temperature recorder in conection with the data coming from a simultaneous BT section.

  15. Martinho Lutero (1483-1546 e Tomás Müntzer (1489-1525: a justificação teológica da autoridade secular e da revolução política

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    Dreher, Martin Norberto

    2006-01-01

    Full Text Available A Reforma em território alemão possui duas figuras, por vezes próximas entre si, por vezes muito distantes: Lutero e Tomás Müntzer. À medida que foi se envolvendo na vida de seus fiéis, Müntzer foi tomando caminhos próprios, discordando de Lutero que este tomava a "Palavra, em sua realidade objetiva, como constitutiva da Igreja, e afirmando que os verdadeiros fiéis são os que possuem a experiência subjetiva do "Espírito". Também contra Lutero, que defende a resistência à autoridade, mas em questões seculares aceita a tirania, Müntzer, que vê a fé fortemente inserida no social, defende a revolução armada contra os príncipes. Müntzer não nega a graça, mas esta possui papel secundário em seu pensamento, enquanto, para Lutero, ela se coloca no centro de suas preocupações teológicas

  16. Tecnogénesis. La construcción técnica de las ecologías humanas (2 Volúmenes (Tomás Sánchez-Criado, Ed.

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    Pablo Santoro

    2009-05-01

    Full Text Available De ser necesaria una aproximación radicalmente reduccionista a un trabajo tan poliédrico, creo que podría resumirse parte del mensaje de Tecnogénesis. La construcción técnica de las ecologías humanas, la ambiciosa obra colectiva editada por Tomás Sánchez Criado, en dos de sus comienzos. El primero es el que abre el breve y hermoso preámbulo escrito por Florentino Blanco: una reflexión, al hilo de la asistencia del autor a un concierto de música vocal contemporánea, sobre la profunda modificación de la gramática musical clásica en la experimentación actual y sobre la confusión cognitiva y emocional a la que esta destrucción de los códigos acostumbrados arroja al espectador.

  17. SÈNECA, L. A.: Tragèdies, edició crítica de Tomàs Martínez Romero, 2 volums, Barcelona, Barcino, 1995 («Els Nostres Clàssics», Col.lecció B, núm. 14-15)

    OpenAIRE

    Pujol i Gómez, Josep

    1998-01-01

    Obra ressenyada: L. A. SÈNECA; edició crítica de Tomàs MARTÍNEZ ROMERO, Tragèdies. Barcelona: Barcino, 1995. Tomàs Martínez fa una edició crítica de les traduccions catalanes medievals de les següents tragèdies de Sèneca: 'Hercules furens', 'Thyestes', 'Thebais (Phoenissiae)', 'Hippolytus (Phaedra)' 'Oedipus', 'Troades', 'Medea' i 'Agamemnon'. A banda de l'edició, tracta qüestions com la difusió tardomedieval de Sèneca a la corona d'Aragó, la bibliografia sobre la diversitat dels mètodes d...

  18. Vardarbība multiplikācijas filmā „Toms Džerijs”: pirmsskolēnu vecāki par bērnu skatīšanās paradumiem un iespējamajiem efektiem

    OpenAIRE

    Timšāne, Ērika

    2007-01-01

    Bakalaura darba temats ir „Vardarbība multiplikācijas filmā „Toms Džerijs”: pirmsskolēnu vecāki par bērnu skatīšanās paradumiem un iespējamajiem efektiem.” Pētījuma problēma ir vardarbība multiplikācijas filmā „Toms un Džerijs”, pirmsskolēnu izpratne par tās saturu. Par teorētisko bāzi kalpo Alberta Banduras Sociālās iemācīšanās teorija. Tiek aplūkotas bērnu auditorijas īpatnības, intereses un efekti, ko izraisa agresija. Kontentanalīzes mērķis ir izpētīt desmit dažādu gadu „Toms un Džer...

  19. Evaluation of the transfer and the accumulation of microcystins in tomato (Solanum lycopersicum cultivar MicroTom) tissues using a cyanobacterial extract containing microcystins and the radiolabeled microcystin-LR ("1"4C-MC-LR)

    International Nuclear Information System (INIS)

    Corbel, Sylvain; Mougin, Christian; Nélieu, Sylvie; Delarue, Ghislaine; Bouaïcha, Noureddine

    2016-01-01

    Microcystins are the most common cyanotoxins and may be expected wherever blooms of cyanobacteria occur in surface waters. Their persistence both in the irrigation water and in the soil can lead to their transfer and bioaccumulation into agricultural plants. The aim of this work was to investigate microcystin accumulation in Solanum lycopersicum cultivar MicroTom. The plant was exposed to either Microcystis aeruginosa crude extracts containing up to 100 μg eq. MC-LR L"−"1 in a soil–plant system for 90 days or pure radiolabeled "1"4C-MC-LR in a hydroponic condition for 48 h. Toxin bioaccumulation in the soil and different plant tissues was assessed both by the PP2A inhibition assay and by liquid chromatography-mass spectrometry (LC/MS/MS). After 90 days of exposure, microcystins persisted in the soil and their free extractable concentrations accumulated were very low varying between 1.6 and 3.9 μg eq. MC-LR kg"−"1 DW. Free MC-LR was detected only in roots and leaves with concentrations varying between 4.5 and 8.1 μg kg"−"1 DW and between 0.29 and 0.55 μg kg"−"1 DW, respectively. By using radioactivity ("1"4C-MC-LR), the results have reported a growing accumulation of toxins within the organs roots > leaves > stems and allowed them to confirm the absence of MC-LR in fruits after 48 h of exposure. The bioconcentration factor (BCF) was 13.6 in roots, 4.5 in leaves, and 1.4 in stems. On the other hand, the results highlight the presence of two radioactive fractions in different plant tissues. The non-extractable fraction of radioactivity, corresponding to the covalently bound MC-LR, was higher than that of the extractable fraction only in roots and leaves reaching 56% and 71% of the total accumulated toxin, respectively. Therefore, results raise that monitoring programs must monitor the presence of MCs in the irrigation water to avoid the transfer and accumulation of these toxins in crops. - Graphical abstract: Bioconcentration factors in organs of the

  20. Evaluation of the transfer and the accumulation of microcystins in tomato (Solanum lycopersicum cultivar MicroTom) tissues using a cyanobacterial extract containing microcystins and the radiolabeled microcystin-LR ({sup 14}C-MC-LR)

    Energy Technology Data Exchange (ETDEWEB)

    Corbel, Sylvain [INRA, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); AgroParisTech, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); Laboratoire Ecologie, Systématique et Evolution, UMR8079, Univ. Paris-Sud/CNRS/AgroParisTech, Université Paris-Sud, F-91405 Orsay (France); Mougin, Christian; Nélieu, Sylvie; Delarue, Ghislaine [INRA, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); AgroParisTech, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); Bouaïcha, Noureddine, E-mail: noureddine.bouaicha@u-psud.fr [Laboratoire Ecologie, Systématique et Evolution, UMR8079, Univ. Paris-Sud/CNRS/AgroParisTech, Université Paris-Sud, F-91405 Orsay (France)

    2016-01-15

    Microcystins are the most common cyanotoxins and may be expected wherever blooms of cyanobacteria occur in surface waters. Their persistence both in the irrigation water and in the soil can lead to their transfer and bioaccumulation into agricultural plants. The aim of this work was to investigate microcystin accumulation in Solanum lycopersicum cultivar MicroTom. The plant was exposed to either Microcystis aeruginosa crude extracts containing up to 100 μg eq. MC-LR L{sup −1} in a soil–plant system for 90 days or pure radiolabeled {sup 14}C-MC-LR in a hydroponic condition for 48 h. Toxin bioaccumulation in the soil and different plant tissues was assessed both by the PP2A inhibition assay and by liquid chromatography-mass spectrometry (LC/MS/MS). After 90 days of exposure, microcystins persisted in the soil and their free extractable concentrations accumulated were very low varying between 1.6 and 3.9 μg eq. MC-LR kg{sup −1} DW. Free MC-LR was detected only in roots and leaves with concentrations varying between 4.5 and 8.1 μg kg{sup −1} DW and between 0.29 and 0.55 μg kg{sup −1} DW, respectively. By using radioactivity ({sup 14}C-MC-LR), the results have reported a growing accumulation of toxins within the organs roots > leaves > stems and allowed them to confirm the absence of MC-LR in fruits after 48 h of exposure. The bioconcentration factor (BCF) was 13.6 in roots, 4.5 in leaves, and 1.4 in stems. On the other hand, the results highlight the presence of two radioactive fractions in different plant tissues. The non-extractable fraction of radioactivity, corresponding to the covalently bound MC-LR, was higher than that of the extractable fraction only in roots and leaves reaching 56% and 71% of the total accumulated toxin, respectively. Therefore, results raise that monitoring programs must monitor the presence of MCs in the irrigation water to avoid the transfer and accumulation of these toxins in crops. - Graphical abstract: Bioconcentration

  1. Análisis bibliométrico de los trabajos de grado del área organizacional de la Facultad de Psicología de la Universidad Santo Tomás

    Directory of Open Access Journals (Sweden)

    María Constanza Aguilar B.

    2007-01-01

    Full Text Available El propósito de esta investigación fue realizar un análisis bibliométrico de los trabajos de grado del área organizacional de la Facultad de Psicología de la Universidad Santo Tomás. Primero, se hizo una revisión todos los trabajos de grado de Psicología (1307 tesis de los cuales se seleccionaron 247 del área producidos durante 26 años, cerca del 19%, –período comprendido entre 1985-2005-. Luego, se diseñó una base de datos y de acuerdo con las variables previamente establecidas se sistematizaron los datos. El estudio fue de tipo descriptivo y se realizan dos tipos de análisis, uno de carácter descriptivo bibliométrico y el segundo, corresponde al análisis de datos textuales. Se encontró que de los 247 trabajos revisados se revelo que 1995 fue el año en el que se desarrollaron mayor número de tesis (50 trabajos; los enfoques teóricos de abordaje de las tesis son de: enfoque sistémico (51 trabajos seguidos por el enfoque cognitivo comportamental (26. Por último, se presento un valioso aporte metodológico, y es la inclusión del análisis de datos textual a la bibliometría, el cual revelo en primer lugar la relación entre la Psicología social y la Psicología organizacional; en segundo lugar se evidenciaron dos periodos donde las temáticas giran en torno a una visión clásica de la psicologia organizacional y en últimos 10 años un énfasis en una perspectiva critica de la psicologia de las organizaciones.

  2. A review of the Tom Rozwadowski medal

    African Journals Online (AJOL)

    His research contributions to the Multiple Criteria Decision Analysis field possibly ..... ment using Soft Systems Methodology and. MCDA Tools ... water distribution system design using a ... Oil Liquid. Innovative Decision Support in a Petro-.

  3. Die Geschichte von Tom Buk-Swienty

    DEFF Research Database (Denmark)

    Rønhede, Søren

    2010-01-01

    Buk-Swienty markedsfører sin seneste bog på en påstand om at have afsløret, at kongen, Christian IX, i 1864 gennem sin anmodning om optagelse i Det tyske Forbund søgte at nedlægge Danmark. Påstanden er uden hold i de historiske realiteter....

  4. PFC Diego Tomás

    OpenAIRE

    Tomás Requena, Diego

    2015-01-01

    Desarrollo de una aplicación móvil que permita buscar y localizar ofertas online. Estas ofertas serán publicadas por los comercios adscritos al proyecto. La idea básica es no tener que encontrar la oferta mientras paseas un día por el centro, si no que puedas buscar, a través de una aplicación móvil, dónde se encuentran esas ofertas. Desenvolupament d'una aplicació mòbil que permet buscar i localitzar ofertes en línia. Aquestes ofertes seran publicades pels comerços adscrits al projecte. L...

  5. Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of São Tomé and Príncipe, West Africa

    Directory of Open Access Journals (Sweden)

    Fan Chia-Kwung

    2012-07-01

    Full Text Available Abstract Background The status of Toxoplasma gondii infection among primary schoolchildren (PSC of the Democratic Republic of São Tomé and Príncipe (DRSTP, West Africa, remains unknown to date. Methods A serologic survey and risk factors associated T. gondii infection among PSC in the DRSTP was assessed by the latex agglutination (LA test and a questionnaire interview including parents’ occupation, various uncomfortable symptoms, histories of eating raw or undercooked food, drinking unboiled water, and raising pets, was conducted in October 2010. Schoolchildren from 4 primary schools located in the capital areas were selected, in total 255 serum samples were obtained by venipuncture, of which 123 serum samples were obtained from boys (9.8 ± 1.4 yrs and 132 serum samples were obtained from girls (9.7 ± 1.3 yrs. Results The overall seroprevalence of T. gondii infection was 63.1% (161/255. No significant gender difference in seroprevalence was found between boys (62.6%, 77/123 and girls (63.6%, 84/132 (p = 0.9. The older age group of 10 years had insignificantly higher seroprevalence (69.9%, 58/83 than that of the younger age group of 8 year olds (67.7%, 21/31 (p = 0.8. It was noteworthy that the majority of seropositive PSC (75.8%, 122/161 had high LA titers of ≥1: 1024, indirectly indicating acute or repeated Toxoplasma infection. Parents whose jobs were non-skilled workers (73.1% showed significantly higher seroprevalence than that of semiskilled- (53.9% or skilled workers (48.8% (p p  Children who claimed to have had recent ocular manifestation or headache, i.e. within 1 month, seemed to have insignificantly higher seroprevalence than those who did not (p > 0.05. Conclusions Parents’ educational level and cats kept indoors seemed to be the high risk factors for PSC in acquisition of T. gondii infection. While, ocular manifestation and/or headache of PSC should be checked for the possibility of being

  6. Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of São Tomé and Príncipe, West Africa.

    Science.gov (United States)

    Fan, Chia-Kwung; Lee, Lin-Wen; Liao, Chien-Wei; Huang, Ying-Chieh; Lee, Yueh-Lun; Chang, Yu-Tai; da Costa, Ângela dos Santos Ramos José; Gil, Vilfrido; Chi, Li-Hsing; Nara, Takeshi; Tsubouchi, Akiko; Akinwale, Olaoluwa Pheabian

    2012-07-13

    The status of Toxoplasma gondii infection among primary schoolchildren (PSC) of the Democratic Republic of São Tomé and Príncipe (DRSTP), West Africa, remains unknown to date. A serologic survey and risk factors associated T. gondii infection among PSC in the DRSTP was assessed by the latex agglutination (LA) test and a questionnaire interview including parents' occupation, various uncomfortable symptoms, histories of eating raw or undercooked food, drinking unboiled water, and raising pets, was conducted in October 2010. Schoolchildren from 4 primary schools located in the capital areas were selected, in total 255 serum samples were obtained by venipuncture, of which 123 serum samples were obtained from boys (9.8 ± 1.4 yrs) and 132 serum samples were obtained from girls (9.7 ± 1.3 yrs). The overall seroprevalence of T. gondii infection was 63.1% (161/255). No significant gender difference in seroprevalence was found between boys (62.6%, 77/123) and girls (63.6%, 84/132) (p = 0.9). The older age group of 10 years had insignificantly higher seroprevalence (69.9%, 58/83) than that of the younger age group of 8 year olds (67.7%, 21/31) (p = 0.8). It was noteworthy that the majority of seropositive PSC (75.8%, 122/161) had high LA titers of ≥1: 1024, indirectly indicating acute or repeated Toxoplasma infection. Parents whose jobs were non-skilled workers (73.1%) showed significantly higher seroprevalence than that of semiskilled- (53.9%) or skilled workers (48.8%) (p raising cats also showed significantly higher seroprevalence than those who did not (p 0.05). Parents' educational level and cats kept indoors seemed to be the high risk factors for PSC in acquisition of T. gondii infection. While, ocular manifestation and/or headache of PSC should be checked for the possibility of being T. gondii elicited. Measures such as improving environmental hygiene and intensive educational intervention to both PSC and their parents should be performed immediately so as to

  7. Aleitamento materno e caracterização dos hábitos alimentares na primeira infância: experiência de São Tomé e Príncipe

    Directory of Open Access Journals (Sweden)

    Diana e Silva

    2014-09-01

    Full Text Available Objetivos: avaliação da amamentação, da diversificação e frequência alimentar, em crianças de São Tomé e Príncipe (STP. Métodos: trata-se de uma amostra constituída por 1285 crianças. O protocolo incluiu a prevalência do aleitamento materno exclusivo (AME e Total (AMT, início da diversificação alimentar (DA e um questionário de frequência alimentar. O tratamento estatístico foi efetuado no SPSS®. Os resultados foram apresentados de acordo com o total da amostra. Resultados: 45,5% são do sexo feminino e a média de idades 26±18 meses. 46,6% fez AME até aos 6 meses (média 5±2. A média de AMT foi 12±7 meses e o início da DA aos 6±3 meses (mediana=6, sendo as farinhas e a canja de peixe os primeiros alimentos oferecidos. 42% das crianças são incluídas na dieta familiar aos 7±3 meses (mediana=6. Elevada porcentagem de crianças nunca ingere: leite de vaca (74% ou iogurte (40%, contrariamente ao elevado consumo de óleo alimentar (34% e açúcar (33%. A idade média de iniciação da cerveja é aos 18±12 meses e vinho de palma 13±10 meses. Conclusões: observa-se uma elevada prevalência de AME e uma precoce introdução da DA. Embora existam recursos alimentares disponíveis, não há informação/ formação adequada para elaborar um plano alimentar saudável durante a infância.

  8. Análisis Del Impacto Del Acompañamiento Psicológico En El Rendimiento Académico De Los Estudiantes De La División De Ingenierías De La Universidad Santo Tomás -Bogotá

    OpenAIRE

    Galán, Lina; Guillén, Sandra; Mogollón, Edna

    2016-01-01

    El acompañamiento y seguimiento a los estudiantes universitarios se ha convertido en una práctica necesaria, con el fin de conocer cuáles son las situaciones por las cuales atraviesan los jóvenes y que pueden llegar a afectar de manera directa su rendimiento. Son insuficientes las tutorías académicas, las cuales no alcanzan a generar una comprensión holística del ser integral que abarca sus demás dimensiones. La Universidad Santo Tomás, tiene como desarrollo misional la formación integral de ...

  9. CIFRAS CON SENTIDO: Articulación Del Proceso De Acompañamiento Estudiantil Con El Sistema De Gestión De La Calidad Del Departamento De Humanidades Y Formación Integral De La Universidad Santo Tomás Bogotá

    OpenAIRE

    Cely Atuesta, Diana Catherine; Riaño, Adriana; Latorre, Kenia

    2016-01-01

    El Departamento de Humanidades y Formación Integral (DHFI), de la Universidad Santo Tomás (USTA) Bogotá - Colombia, es una instancia académica que tiene como misión “promover los procesos de Formación Integral de la Comunidad Universitaria y aportar elementos para desarrollar actitud y conciencia críticas, a la luz del pensamiento tomista de la educación” (Documento Marco DHFI, 2014). Las cátedras del DHFI hacen parte de los planes de formación de todos los programas de la USTA a partir de 7 ...

  10. Aspectos econômicos da produção e do risco nos sistemas agroflorestais e nos sistemas tradicionais de produçâo agrícola em tomé-açu, Pará - 2001 a 2003 Economic aspects of production under risk conditions in agroforestry systems and traditional agricultural systems in tomé-açu, Pará - 2001 to 2003

    Directory of Open Access Journals (Sweden)

    Luiz Benedito Varela

    2009-02-01

    Full Text Available Neste artigo, analisaram-se os fatores determinantes da produção dinâmica dos sistemas agroflorestais (SAF e dos sistemas tradicionais de produção agrícola (ST, sob condições de risco, em pequenas e médias unidades produtivas nipo-brasileiras localizadas no Município de Tomé-Açu, Pará, no período de 2001 a 2003. Os resultados indicaram que todos os fatores, exceto a mão-de-obra contratada e as máquinas e equipamentos, afetam diretamente o Valor Bruto da Produção (VBP dos SAF e dos ST; a variável dummy apresentou diferença cumulativa a menor no VBP dos SAF, de um ano para outro. A função de risco estimada apontou que os SAF apresentaram menor risco que os ST, evidenciando-se que a aplicação de insumos era fonte de redução de risco, mas a tecnologia adotada precisa ser adequada, pois se apresenta como fator de aumento de risco nos dois sistemas. Além disso, a dummy indicou que os SAF exibiram menor nível de risco que os ST. Nesse contexto, os resultados deixaram claro, ainda, que os produtores nipo-brasileiros eram avessos ao risco.This article analyzes the determinants of the dynamic production inputs of the agroforestry systems (SAF and traditional agricultural systems (ST under risk conditions, in small and medium farms in Tome-Açu, Pará, by Brazilian-Japanese producers from 2001 to 2003. The dynamic regression model results showed that all the inputs, except labor and machinery, have positive impacts on the current VBP of the two systems analyzed. Furthermore, the dummy variable shows a minor accumulative difference of the SAF's VBP in comparison with ST's VBP, from one period (year to another. The estimated risk function indicates that the use of fertilizer and pesticides reduce the risk level of the two systems, but the current technology needs to be adequate to other production inputs, since it appears as a factor of increased risk to the two systems. In addition, the dummy variable indicates that the SAF

  11. Article Molecular analysis of three FUT3 gene single nucleotide polymorphisms and their relationship with the lewis erythrocytary phenotype in a human population of japanese-ancestry living in Tomé Açu, a town in the Brazilian Amazon

    Directory of Open Access Journals (Sweden)

    Pablo Abdon da Costa Francez

    2007-03-01

    Full Text Available The Lewis blood group system involves two major antigens, Leª and Le b. Their antigenic determinants are not primary gene products but are synthesized by the transfer of sugar subunits to a precursory chain by a specific enzyme which is the product of the FUT3 gene (Lewis gene. The presence of three FUT3 gene single nucleotide polymorphisms (SNPs (59T > G; 508G > A and 1067T > A was related to the Lewis phenotype of erythrocytes from 185 individuals of Japanese ancestry living in the town of Tomé-Açu in the Brazilian Amazon region. This relationship was detected using a serological hemagglutination test and the Dot-ELISA assay along with the molecular technique PCR-RFLP. We found that the three SNPs investigated in this study only accounted for a proportion of the Lewis-negative phenotype of the erythrocytes.

  12. Nas franjas do império ultramarino português: a experiência insular de São Tomé e Príncipe no despertar dos oitocentos In the far-flung corners of the Portuguese overseas Empire: the island experience of Sao Tome and Principe at the beginning of the 19th century

    Directory of Open Access Journals (Sweden)

    Neuma Brilhante

    2009-01-01

    Full Text Available São Tomé e Príncipe ocupou importante lugar na arquitetura imperial no século XVI. Contudo, a capitania tornou-se cada vez mais periférica no contexto do império português em decorrência de sérios problemas internos e dos deslocamentos do comércio colonial. As iniciativas reformistas experimentadas no início dos oitocentos fracassaram diante das importantes mudanças político-econômicas que envolveram o tráfico atlântico, principalmente, das ações inglesas contra esse comércio.Sao Tome and Principe held an important position within the Portuguese Empire in the 16th century. However due to serious internal conflicts and the transfer of priorities in colonial trade, this colonial island was gradually relegated. At the onset of the 19th century, a new administrative reform failed to restore their former affluence because of the consequences of important politico-economic changes concerning transatlantic trade, mainly, the British intervention against this trading.

  13. Läti koostöökogude liikmed Hiiumaal / Harda Roosna

    Index Scriptorium Estoniae

    Roosna, Harda, 1956-

    2008-01-01

    Läti Salduse ja Kandava piirkonna Leader koostöökogude liikmed käisid õppereisil Saaremaal ja Hiiumaal. Artikkel sisaldab ka intervjuud MTÜ Salduse Piirkonna Arendamise Ühenduse esinaise Sarmite Ozolina ja MTÜ Kandava Partnerlus juhatuse esimehe Girts Kindzulisega

  14. Johannes Vermeer and Tom Gouws: textual discourse through pen ...

    African Journals Online (AJOL)

    Poems such as 'ars poetica' and 'die kantklosser' will be read as speaking paintings of visual texts and visual writing through which an exceptional merger of pen and brush come into being. Keywords: iconicity, tipography, cohesion, visual text, ars poetica, syntactic chiasm, texture, canto. Journal for Language Teaching Vol ...

  15. Early data from Aura and continuity from UARS and TOMS

    NARCIS (Netherlands)

    Hilsenrath, E.; Schoeberl, M.R.; Douglass, A.R.; Bhartia, P.K.; Barnett, J.J.; Beer, R.; Waters, J.W.; Gunson, M.R.; Froidevaux, L.; Gille, J.C.; Levelt, P.F.

    2006-01-01

    Aura, the last of the large EOS observatories, was launched on July 15, 2004. Aura is designed to make comprehensive stratospheric and tropospheric composition measurements from its four instruments, HIRDLS, MLS, OMI and TES. These four instruments work in synergy to provide data on ozone trends,

  16. Privaatne - Läti kaasaegne fotokunst / Toms Ķencis

    Index Scriptorium Estoniae

    Ķencis, Toms

    2010-01-01

    Läti fotograafia näitus "Private: Contemporary Photo Art in Latvia" Riias 20. augustist 18. oktoobrini 2009, kuraator Alise Tifentāle. Lähemalt Arnis Balčus'i, Gunārs Binde, Zenta Dzividzinskat'i, Roman Korovini, Inta Ruka, Alnis Stakle, Vilnis Vītoliņš'i loomingust

  17. (In) Famous Spirituality : Harriet Beecher Stowe's Uncle Tom

    NARCIS (Netherlands)

    Visser, I.

    2008-01-01

    After the Egyptian and the Indian, the Greek and Roman, the Teuton and Mongolian, the Negro is a sort of seventh son, born with a veil, and gifted with second sight in this American world-a world which yields him no true self-consciousness, but only lets him see himself through the revelation of the

  18. Tarneahela juhtimine annab konkurentsieelise / Tom Vollmann, Carlos Cordon, Hakon Raabe

    Index Scriptorium Estoniae

    Vollmann, Tom

    2003-01-01

    Autorid selgitavad tarneahela juhtimise mõistet, kirjeldavad tarneahela kaardistamise ja juhtimise metoodika rakendamise võimalusi äritegevuses kulude vähendamiseks, väärtuse suurendamiseks ning jaotusahela konkurentsivõime tõstmiseks

  19. Overflødige ord, tom jargon og forkludrede udtryk

    DEFF Research Database (Denmark)

    Kock, Christian Erik J

    2014-01-01

    Professor i retorik Christian Kock kaster et blik på Højberg Rapporten, der indeholder 23 anbefalinger til bedre kommunikation på Københavns Universitet. Han mener ikke, at rapporten selv kan tjene som eksempel på vellykket kommunikation....

  20. Tom ja Anni said suureks / Kairit Tsäro

    Index Scriptorium Estoniae

    Tsäro, Kairit, 1974-

    2011-01-01

    ETV staažikas lastesaade "Saame kokku Tomi juures" lõpetab. Saate produtsent Margus Saar, Anni - Maria Soomets ja postiljon Eedi - Kalju Orro, vaatavad tagasi viiele aastale ja meenutavad saatekülalisi

  1. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, TOM GREEN COUNTY, TEXAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  2. Tom test 8/26/02 11:45am

    Science.gov (United States)

    2000-01-01

    Members of the flight and ground crews prepare to unload equipment from NASA's B377SGT Super Guppy Turbine cargo aircraft on the ramp at NASA's Dryden Flight Research Center at Edwards Air Force Base, Calif. The outsize cargo plane had delivered the latest version of the X-38 flight test vehicle to NASA Dryden when this photo was taken on June 11, 2000. The B-377SGT Super Guppy Turbine evolved from the 1960s-vintage Pregnant Guppy, Mini Guppy and Super Guppy, used for transporting sections of the Saturn rocket used for the Apollo program moon launches and other outsized cargo. The various Guppies were modified from 1940's and 50's-vintage Boeing Model 377 and C-97 Stratocruiser airframes by Aero Spacelines, Inc., which operated the aircraft for NASA. NASA's Flight Research Center assisted in certification testing of the first Pregnant Guppy in 1962. One of the turboprop-powered Super Guppies, built up from a YC-97J airframe, last appeared at Dryden in May, 1976 when it was used to transport the HL-10 and X-24B lifting bodies from Dryden to the Air Force Museum at Wright-Patterson Air Force Base, Ohio. NASA's present Super Guppy Turbine, the fourth and last example of the final version, first flew in its outsized form in 1980. It and its three sister ships were built in the 1970s for Europe's Airbus Industrie to ferry outsized structures for Airbus jetliners to the final assembly plant in Toulouse, France. It later was acquired by the European Space Agency, and then acquired by NASA in late 1997 for transport of large structures for the International Space Station to the launch site. It replaced the earlier-model Super Guppy, which has been retired and is used for spare parts. NASA's Super Guppy Turbine carries NASA registration number N941NA, and is based at Ellington Field near the Johnson Space Center. For more information on NASA's Super Guppy Turbine, log onto the Johnson Space Center Super Guppy web page at http://spaceflight.nasa.gov/station/assembly/superguppy/

  3. Integrating TOM into environmental projects, Angela B. Quinlan

    International Nuclear Information System (INIS)

    Caldwell, J.A.

    1992-01-01

    Responsible and cost-effective waste management and environmental restoration are best achieved when the principles and procedures of Total Quality Management are made an integral part of the process. By describing three case histories, we explore and explain techniques for using TQM in environmental projects. Key aspects considered include: quality measurement systems; establishing and maintaining standard operating procedures; management and technical peer review; the use of Quality Improvement Teams; Roadmapping (a new procedure that the US Department of Energy is incorporating into environmental restoration programs); and the role of audit teams in document production. The three case histories covered include: The Department of Energy's Uranium Mill Tailings Remedial Action Project on which Roadmapping and Quality Improvement Teams have led to significant changes in procedures; the EPA ARCS program on which adoption of project management Standard Operating Procedures enhanced cost and schedule control; the Jacobs Engineering TQM program that emphasizes performance measurement and management and project technical peer review

  4. 'Tom & Viv' ehk Elulugu kunstiks / Jaak Rähesoo

    Index Scriptorium Estoniae

    Rähesoo, Jaak, 1941-

    1996-01-01

    Mängufilm Thomas Stearns Eliotist Michael Hastingsi näidendi põhjal, stsenaristid Michael Hastings ja Adrian Hodges, re̓issöör Brian Gilbert : Suurbritannia, 1994. Ka autori suhtumisest Madis Kõivu ja Jaan Krossi biograafilistesse teostesse. Järg: 26. jaan., lk. 12

  5. Schaulust und Horror Soziokulturelle - Perspektiven auf PEEPING TOM

    Directory of Open Access Journals (Sweden)

    Thomas Ballhausen

    2010-09-01

    Full Text Available Die Geschichte des Kinos und des Films ist mindestens ebenso sehr eine Geschichte des Schreckens (und der damit verbundenen Schaulust wie sie eine Geschichte des Dokumentarischen zu sein scheint. Es sind die außergewöhnlichen Körper und deren Bewegungen, die das Publikum zu allen Zeiten faszinierten, schockierten und zum Schauen und Sehen lockten. Besonders das Genre des Horrorfilms ist mit diesem zentralen Aspekt des Kinos besonders deutlich verbunden.

  6. Factores que inciden en el proceso de enseñanza - aprendizaje del español como segunda lengua (L2, segundo grado, escuela “Santo Tomás de Umbra”, segundo semestre del año 2007.

    Directory of Open Access Journals (Sweden)

    Leandro Pekitle Pedro

    2012-09-01

    Full Text Available La temática se fundamenta en los factores que inciden en el proceso de enseñanza - aprendizaje del español como segunda lengua (L2, segundo grado de Educación Primaria, escuelabilingüe en la comunidad: “Santo Tomás de Umbra”, segundo semestre del 2007. Asimismo, identifica los factores socioeconómicos que influyen para que la niñez aprenda hablar elespañol durante su escolaridad. La metodología aplicada fue participativa, activa e interactiva entre los investigadores y los participantes en la investigación (la comunidad dado el enfoque etnográfico de la investigación, se aplicaron instrumentos como guías de entrevistas semi - estructuradas y grupos focales para madres y padres de familia, estudiantes, docentes, directores de la comunidad.Los resultados reflejan diversas situaciones que dificultan que la niñez aprenda a hablar el español como segunda lengua para la socialización y necesidades de comunicación con otras personas, destacando el factor pedagógico, la ausencia de capacitaciones, el desconocimiento y aplicación de metodologías pertinentes para la enseñanza de segunda lengua por parte de la maestra. Entre las conclusiones es que uno de los mayores problemas que incide de forma negativa en el aprendizaje del español, es la no aplicación de una metodología pertinente y el desconocimiento de las habilidades lingüísticas para que la niñez pueda ampliar su repertorio verbal para diversos fines. Así como la poca práctica del español por parte de la niñez en la comunidad. Por lo cual se recomienda a las instancias correspondientes como el MINED- PEBI, tomar cartas en el asunto para brindar mayor atención a los docentes de la comunidad, en materia de capacitación y especialmente en aplicación de metodologías para enseñanza del español y conocimientos básicos sobre lingüística.

  7. Depreciação no Brasil e na Alemanha: as diferenças na aplicação a um tomógrafo e construção anexa = Depreciation in Brazil and Germany: differences in a Ct Scan and an Attached Building

    Directory of Open Access Journals (Sweden)

    Charles Albino Schultz

    2009-03-01

    Full Text Available O presente estudo é uma análise das diferentes abordagens da depreciação na legislação fiscal no Brasil e na Alemanha. Foi realizada por meio de um estudo descritivo que simula a aplicação das diferentes fórmulas de cálculo das parcelas de depreciação deum tomógrafo e da construção anexa em um hospital universitário público e um hospital privado. A legislação fiscal brasileira mostrou-se mais simples que a alemã, contudo, ao mesmo tempo, permite um número indefinido de alternativas de depreciação, por ser possível a adoção de fórmulas de cálculo diferentes das especificadas na legislação. Além disso, constatou-se a ausência de uma legislação sobre a depreciação em instituições públicas. Já, na Alemanha, a legislação permite mais fórmulas de cálculo, entretanto, com parâmetros rígidos de enquadramento em determinados métodos utilizados como incentivo. A utilização da depreciação como forma de atribuir incentivos à renovação tecnológica e ao desenvolvimento de setores específicos é idêntica em ambos os países e, normalmente, é exercida por meio da depreciação acelerada. Uma característica específica da legislação alemã consiste no fato desta ser aplicada tanto a hospitais particulares quanto a hospitais públicos, enquanto que no Brasil a depreciação é exclusiva à contabilidade das empresas privadas.This study is an analysis of several different approaches of the reduction of the taxlegislation in Brazil and Germany. It was accomplished through a descriptive study thatsimulates the application of different formulas for calculating depreciation of portionsof a CT scan and the building attached to a public university hospital and a privatehospital. The Brazilian tax legislation proved to be simpler than the German, however,at the same time it allows an indefinite number of alternatives for depreciation, once itis possible the adoption of different formulas for calculating from

  8. Evaluación ambiental de los fondos documentales de la biblioteca Tomás Navarro Tomás del CCHS-CSIC

    Directory of Open Access Journals (Sweden)

    Peña-Poza, Javier

    2011-03-01

    Full Text Available The most innovative procedure for preventive conservation of library holdings, especially those of historical interest, lies in the evaluation of environmental parameters witch have a negative effect on the conservation of such materials. The application of sensors permits for full, accurate and secure monitoring of environmental conditions and allows for the prediction of chemical-physical mechanisms of degradation, as well as of the most suitable procedures for controlling them. The sensors used in the present study were prepared by the sol-gel method and change colour when variations in the evaluated parameters occur. All of the sensors are reversible, reusable and can be regenerated. Temperature, relative humidity, illumination and acidity were the parameters evaluated. In the first stage, conventional apparatus were used to determine the critical ranges of variation for such parameters. Subsequently optical sensors sensitive in such ranges were designed and prepared. These sensors were calibrated and distributed throughout the rooms containing the holdings (approximately 3.200 square meters. The optical response of the sensors (change of colour was recorded by visible spectrophotometry during the spring and summer of 2009. The use of sensors has the following advantages: low cost, no need for wires or apparatus during exposure, small size, reversibility, and short response time. The resulting data have revealed the environmental conditions of the conservation of the holdings, including environmental acidity, a parameter that could not be evaluated previously through conventional procedures.

    El procedimiento más innovador de conservación preventiva de los fondos documentales de bibliotecas, especialmente los de carácter histórico, consiste en la evaluación de los parámetros ambientales que afectan negativamente a la conservación de los materiales implicados. La aplicación de sensores permite la monitorización completa, precisa y segura de las condiciones ambientales, predecir los mecanismos quimicofísicos de degradación y los procedimientos más adecuados para controlarlos. Los sensores de este estudio se prepararon por el procedimiento sol-gel y experimentan un cambio de color cuando varían los parámetros a evaluar. Todos los sensores son reversibles, regenerables y reutilizables. Los parámetros evaluados han sido temperatura, humedad relativa, iluminación y acidez. En la primera etapa se utilizaron aparatos convencionales para determinar los intervalos críticos de variación de dichos parámetros. Posteriormente se diseñaron y prepararon sensores ópticos con sensibilidad en esos intervalos, se calibraron y se distribuyeron en las salas de los fondos documentales (aproximadamente 3.200 m2. La respuesta óptica de los sensores (cambio de color se registró mediante espectrofotometría visible durante la primavera-verano de 2009. El uso de estos sensores presenta las siguientes ventajas: bajo coste, ausencia de cables y aparatos durante la exposición, pequeño tamaño, reversibilidad y tiempos cortos de respuesta. Los resultados han permitido conocer las condiciones ambientales de conservación de los fondos documentales, incluyendo la acidez ambiental que hasta ahora no es posible evaluar con los procedimientos convencionales disponibles.

  9. Price rules in airline marketing / Elina Krauja-Veide, Marina Jõgi, Toms Andersons...[jt.

    Index Scriptorium Estoniae

    2004-01-01

    Lennukompaniide Air Baltic, Estonian Air, British Airways ja Lithuanian Airlines turundusjuhid olukorrast Baltimaade lennundusturul ja lennufirmade turundustegevusest. Kommenteerivad Priit Kivik, Ilona Kbejan, Julia Brjuhanova. Tabel

  10. Barb'ra Allen, Tom Dooley, and Sweet Betsy from PS 42.

    Science.gov (United States)

    Praver, Jerry; Praver, Bev

    1984-01-01

    Folk music is not necessarily old, anonymous, or unwritten. Its most important characteristic is change through the folk process. Folk music is a part of our national heritage that children can usually acquire only in school. It can be used to support a variety of school subjects. (CS)

  11. A Community Terrain-Following Ocean Modeling System (ROMS/TOMS)

    Science.gov (United States)

    2013-09-30

    workshop at the Windsor Atlântica Hotel, Rio de Janeiro , Brazil, October 22-25, 2012. As in the past, several tutorials were offered on basic and...from the European Centre For Medium-Range Weather Forecasts (ECMWF) ERA-Interim, 3-hour dataset. River runoff is included along the Alabama

  12. Inzicht fotosynthese belangrijk voor CO2 doseren en belichten (interview met Tom Dueck)

    NARCIS (Netherlands)

    Kierkels, T.; Heuvelink, E.; Dueck, T.A.

    2014-01-01

    Vroeger was het vooral een curiositeit dat er planten bestaan die voornamelijk ’s nachts CO2 binden, de CAM-planten. Maar het is in de glastuinbouw geen uitzondering meer. Inmiddels hoort de best verkochte potplant – phalaenopsis – tot deze groep. Dus dan dringen zich vragen op als: wanneer gedragen

  13. O tom do cuidado de enfermagem para alunos de graduação

    Directory of Open Access Journals (Sweden)

    Fátima Helena do Espirito Santo

    2000-03-01

    Full Text Available Embora o cuidado seja apontado como essência da Profissão pouco se discute sobre seus significados no ensino de enfermagem. O trabalho objetivou identificar o significado do cuidado para alunos visando contribuir para um ensino mais contextualizado. Para guiar o estudo utilizamos os conceitos de filiação e noção de membro da Etnometodologia. Os sujeitos foram alunos do Curso de Graduação em Enfermagem de uma instituição do Estado do Rio de Janeiro. Os dados foram coletados através de entrevistas semi-estruturadas após dinâmica de grupo que buscou apreender como os alunos descreviam o cuidado até aquele momento do curso. Concluímos que na medida em que os alunos vão se filiando à Enfermagem, incorporam conceitos que contribuem para reforçar ou transformar o que trouxeram de experiências anteriores e daquelas vividas durante o curso de graduação. Logo, conceitos e comportamentos vão sendo apreendidos e reproduzidos pelo aluno como componentes de sua identidade profissional.

  14. Tom ja Anni ajavad isad-emad naerma / Kai Väärtnõu

    Index Scriptorium Estoniae

    Väärtnõu, Kai

    2007-01-01

    ETV lastesaate "Saame kokku Tomi juures" stsenarist on Jaak Urmet ehk Wimberg. Teksti improviseerivad ka näitlejad Karol Kuntsel ja Maria Soomets. Lisaks tutvustus "Pööningule purjetab proua Õietolmutuust"

  15. Jubileuszowy tom zbiorowy („Festschrift”) jako interakcyjny i intertekstualny gatunek komunikacji naukowej

    Czech Academy of Sciences Publication Activity Database

    Hoffmannová, Jana

    -, č. 6 (2013), s. 359-372 ISSN 1899-0983 R&D Projects: GA ČR GAP406/12/1829 Institutional support: RVO:68378092 Keywords : scientific discourse * genre * intertextuality * interaction * dedication * speech acts * stylistics * rhetorics Subject RIV: AI - Linguistics

  16. Keskerakond tasub slovaki annetuste eest Brüsselis / Tom Nicholson

    Index Scriptorium Estoniae

    Nicholson, Tom

    2009-01-01

    Autori väitel on Slovakkia ärimeeste mitmekümne tuhande euro suurune annetus Keskerakonnale seotud Slovakkia Rahvapartei püüdlusega ühineda Euroopa Parlamendi ALDE fraktsiooniga. Keskerakond on ALDE liige

  17. Polymer materials for roll coated solar cells: strategies tom improve performance and stability

    DEFF Research Database (Denmark)

    Heckler, Ilona Maria

    Solar cells are among the renewable energy technologies with a large potential in terms of solar energy availability. The solar cells based on conjugated polymers belong to the third generation of this technology and their attractive features include a fast and cheap solution‐processed production...

  18. Richard Wright's Thematic Treatment of Women in "Uncle Tom's Children,""Black Boy," and "Native Son."

    Science.gov (United States)

    Brewton, Butler E.

    Richard Wright's literary work emphasizes a contrast between black women and white women. Although both are "givers" to black boys, the nature of what they give is different. The black woman gives physical life, feeds it, and protects it at the expense of spiritual or creative vitality. Her goal is to survive bodily, to breathe, to have…

  19. Contemporary Thinking about Causation in Evaluation: A Dialogue with Tom Cook and Michael Scriven

    Science.gov (United States)

    Cook, Thomas D.; Scriven, Michael; Coryn, Chris L. S.; Evergreen, Stephanie D. H.

    2010-01-01

    Legitimate knowledge claims about causation have been a central concern among evaluators and applied researchers for several decades and often have been the subject of heated debates. In recent years these debates have resurfaced with a renewed intensity, due in part to the priority currently being given to randomized experiments by many funders…

  20. Risico's 'groen' gas voor CO2 - dosering ingeschat : Interview met Tom Dueck en Chris van Dijk

    NARCIS (Netherlands)

    Visser, Peter; Dueck, T.A.; Dijk, van C.J.

    2009-01-01

    De overheid wil gebruik van duurzaam 'groen gas' ofwel 'biogas' stimuleren. De vraag is of dit gas een verhoogd risico oplevert bij het gebruik van rookgassen voor CO2-dosering in de tuinbouw. Biogas kan mee helpen aan het gebruik van duurzamer energie in de glastuinbouw

  1. Tom Bevill Upper Lock Approach, Tennessee-Tombigbee Waterway, Alabama: Hydraulic Navigation Investigation

    National Research Council Canada - National Science Library

    Winkler, Michael

    2003-01-01

    .... The lock is connected to the dam with a 150-ft abutment wall. A strong crosscurrent or outdraft existing in and around the upstream lock entrance causes difficulty for tow traffic navigating the lock...

  2. Outdraft at Lock Approach, Tom Bevill Lock and Dam, Alabama: Hydraulic Model Investigation

    National Research Council Canada - National Science Library

    Lynch, Gary

    2001-01-01

    .... The lock is connected to the dam with a 150-ft abutment wall. A strong crosscurrent or outdraft existing in and around the upstream lock entrance causes difficulty for tow traffic navigating the lock...

  3. To Find an Image: Black Films from Uncle Tom to Super Fly.

    Science.gov (United States)

    Murray, James P.

    This book surveys the roles of blacks in the film industry. The introduction discusses the question if why there should be a black cinema. The seventeen sections of the book discuss such people and topics as the black actor, movies and life and black people, Sidney Poitier as the black superstar, Diahann Carroll and black female singers in movies,…

  4. Tom W. Bonner Prize in Nuclear Physics Talk: Finding Real Nuclei in Imaginary Time

    Science.gov (United States)

    Pieper, Steven C.

    2010-02-01

    Ab initio calculations of nuclei treat a nucleus as a system of A nucleons interacting by realistic two- (N ) and three-nucleon (N ) forces. Variational Monte Carlo (VMC) followed by Green's function Monte Carlo (GFMC) is a very successful ab initio method for light nuclei. The VMC gives an upper bound to the true energy of a nucleus for a given Hamiltonian; the closeness of the upper bound to the exact solution of the Schr"odinger equation depends on the physical insight built into the trial wave function, ψT, that is used. GFMC starts with a ψT and, by propagation in imaginary time, allows the exact lowest eigenenergy for a given set of quantum numbers to be computed. The first VMC calculations of nuclei were published in 1981 by Lomnitz-Adler, Pandharipande, and Smith. They were for ^3H and ^4He using the Reid N potential. Six years later, Carlson published the first GFMC calculations of nuclei, again for ^3H and ^4He, but using a slightly-simplified N potential; in the following year he used the full Reid V8 potential. Pudliner, Pandharipande, Carlson, and Wiringa published GFMC calculations of A=6 nuclei in 1995, using the Argonne V18 N potential and the Urbana IX N potential. Since then there has been steady progress in applying GFMC to larger nuclei. This has been from both increasing computer power and new or improved algorithms. The largest computers are increasingly difficult to use efficiently, but, as a result of a SciDAC collaboration, we now get excellent scalability up to 131,000 cores on Argonne's IBM Blue Gene/P. In addition we have found that the GFMC can be used for multiple states with the same quantum numbers. With the Argonne V18 and Illinois N potentials, we obtain an excellent description of the properties of nuclei up to A = 12. I will describe these methods, present recent advances in using the largest computers, and some recent results. )

  5. Problems of nuclear reactor safety. Vol. 1; Problemy bezopasnosti yaderno-ehnergeticheskikh ustanovok. Tom 1

    Energy Technology Data Exchange (ETDEWEB)

    Shal` nov, A V [Moskovskij Inzhenerno-Fizicheskij Inst., Moscow (Russian Federation)

    1996-12-31

    Proceedings of the 9. Topical Meeting `Problems of nuclear reactor safety` are presented. Papers include results of studies and developments associated with methods of calculation and complex computerized simulation for stationary and transient processes in nuclear power plants. Main problems of reactor safety are discussed as well as rector accidents on operating NPP`s are analyzed.

  6. International relations among Tom Thumbs: Taiwan as provider of aid Central America

    Directory of Open Access Journals (Sweden)

    Francisco Javier Haro Navejas

    2007-06-01

    Full Text Available This paper analyzes the Official Development Aid (AOD that has as its source Taiwan and as its destination Central America. It has three basic aims: Firstly, there is a huge bibliographic vacuum on the topic of these pages. Beginning filling it is an academic need. Even some intellectuals feel that they should lean against either Beijing or Taipei, that if they write on Taiwan they should defend or attack one of the contending parties. Here it is seen that a study close to objectivity is possible. Secondly, most of the research in International Relations has been focused on topics related with power itself or with just elements related with hard power. AOD is both hard and soft power, therefore this paper shades light to the dark side partially viewing international relations from a theoretical perspective were interactions help to construct identities and cooperation is an essential variable of world politics. Finally, it will be seen below that the Taiwanese cooperativeeconomic actions are helpful to the progress of poor parts of the Central American region and are helpful to create domestic markets with strong links with the world market deepening the economic integration both regional and global. Aid from Taiwan and some other countries, mainly through the transmission of know how, could be of assistance in surmounting huge troubles. Aid is vital because some of Central American’s problems are being exported mainly to México and the United States under the form, just to give an example, of Mara Salvatrucha gangs source of violence and drug trafficking. It is not meaningless to stress that Taiwanese ODA is by far not enough and is very small in the international context.

  7. Minors and informed consent : a comparative approach / Loes Sultiens, Tom Goffin, Pascal Borry...[jt.

    Index Scriptorium Estoniae

    2007-01-01

    Euroopa Nõukogu "Inimõiguste ja biomeditsiini konventsiooni" artikli 6 (Nõusoleku andmiseks võimetu isiku kaitse) täitmise võrdlev analüüs erinevate Euroopa riikide siseriikliku õiguse kontekstis. Eesti kohta lk. 26-27

  8. Constructing National Unity. Commemorations of Tomáš G. Masaryk´s Death

    Czech Academy of Sciences Publication Activity Database

    Hájková, Dagmara

    2012-01-01

    Roč. 4, č. 1 (2012), s. 33-55 ISSN 1803-9243 R&D Projects: GA ČR GAP410/10/0544 Institutional research plan: CEZ:AV0Z70900502 Keywords : Masaryk, T. G. * Czechoslovakia, history * national identity Subject RIV: AB - History

  9. Social infrastructure to integrate science and practice: the experience of the Long Tom Watershed Council

    Science.gov (United States)

    Rebecca L. Flitcroft; Dana C. Dedrick; Courtland L. Smith; Cynthia A. Thieman; John P. Bolte

    2009-01-01

    Ecological problem solving requires a flexible social infrastructure that can incorporate scientific insights and adapt to changing conditions. As applied to watershed management, social infrastructure includes mechanisms to design, carry out, evaluate, and modify plans for resource protection or restoration. Efforts to apply the best science will not bring anticipated...

  10. The Duality Motif in Tom Stoppard's Rosencrantz and Guildenstern Are Dead

    OpenAIRE

    TIEDEMANN, Mark

    2004-01-01

    これは、ローゼンクランツとギルデンスターンは死んだという劇の中の、様々な問題点に関する、トム・ストッパードの考察における二重性の使い方の分析である。二つずつ様々な問題点を紹介すること、例えば芸術と現実、決定論と自由論、生と死が劇の中の構造組織を形成する。また、お互いに鏡のように映し合いながら演じることで、ストッパードは問題点を解明できる。...

  11. Tomás Harris e a memória fraturada da América

    Directory of Open Access Journals (Sweden)

    Felipe Oliver

    2013-06-01

    Full Text Available Escrito durante la dictadura de Augusto Pinochet, Cipango[1992] pone en escena la alianza entre las escrituras oficiales y los intereses políticos de la ciudad letrada. En efecto, en su magnífico poemario Harris revisa no precisamente la historia sino cómo y bajo qué condiciones de poder se escribió el discurso sobre la fundación del Nuevo Mundo, detectando en la violencia y la tortura un vínculo entre la Conquista de la Indias y el reciente gobierno militar chileno. Así, a través de los silencios y la sistemática interrupción del verso, Harris “utiliza” al poemario como un instrumento para develar las fracturas del discurso histórico.

  12. Spirituaalne ruum vaimsuse otsingutes = Sacred spaces as a medium for connecting people in their search for spirituality / Tom Callebaut

    Index Scriptorium Estoniae

    Callebaut, Tom

    2015-01-01

    Essees vaadeldakse arhitektuuri kui vahendit pakkumaks inimestele võimalust luua oma spirituaalne nägemus ja kogemus. Spirituaalse ruumi loomisel võetakse aluseks, et luuakse koht, kus inimestele antakse võimalus arendada individuaalselt või kollektiivselt oma spirituaalset identiteeti.

  13. Strong enhancement of Penning ionization for asymmetric atom pairs in cold Rydberg gases: the Tom and Jerry effect

    KAUST Repository

    Efimov, D K; Miculis, K; Bezuglov, N N; Ekers, Aigars

    2016-01-01

    with which feature autoionization widths that are enhanced by several orders of magnitude compared to that of two atoms in the initial laser-excited state n 0. We also show that in the high-density regime of cold Rydberg gas experiments the ionization rate

  14. Five Years of Humanitarian Missions in São Tomé and Príncipe

    Directory of Open Access Journals (Sweden)

    Cristina Caroça

    2016-01-01

    We have witnessed a considerable improvement on the children to whom we have adapted prosthetics. Some of them return to school, have friends and became more social. As the result of this work, we conclude that all Humanitarian Missions must be adapted to each country’s needs as we have done over the past five years.

  15. Temmen en verontrusten: de atoombom in de strripverhalen Blake en Mortimer en Tom Poes (1946-1960)

    NARCIS (Netherlands)

    D. van Lente (Dick)

    2006-01-01

    textabstractUsing the ideas of Hannah Arendt and Jerome Bruner on the interpretive meaning of stories, the article analyses the contrasting images of the atom bomb in two very popular comics series in the Netherlands. One series attempted to reassure the readers about the impact of the new weapon,

  16. Tom Stoppard'ın Rosencrantz ve Guildenstern Öldüler Adlı Oyununda Mizah ve Kader

    OpenAIRE

    Erkan, Ayça Ülker

    2016-01-01

    Bu çalışmanın amacı karakterlerin kimlik arayışından kaynaklanan fiziksel mizahı tartışmak ve oyundaki ölüm/şans/kader/gerçeklik/yanılsama gibi temaların Rosencrantz ve Guildenstern’nin varoluşçu hayatlarında nasıl işlediğini göstermektir. Mizah, bu trajikomedinin analiz edilmesinde önemli bir rol oynar. Absürd Tiyatro, insanlık durumundaki saçmalığı ifade eder, rasyonel aygıtların kullanımını terk eder, insanın trajik kaybolmuşluk duygusunu yansıtır ve insanlık durumu olan hayat ve ölümle il...

  17. Contr rol of r root-kn saw not nem wdust matod in tom e by u mato ro ...

    African Journals Online (AJOL)

    SAM

    proved with visualizing mical level a ot-knot nema ard dust ame dust. by- and accum ..... Table 2. Effect of sawdust on length of shoot and root (cm) of tomato plants. ...... Evaluation of powdered pine bark for control of Meloidogyne arenaria.

  18. Europski sustav osposobljavanja osoba za vozače vozila na motorni pogon i mjesto Republike Hrvatske u tom sustavu

    Directory of Open Access Journals (Sweden)

    Nenad Zuber

    2012-10-01

    Full Text Available The analytical data on the status of road traffic safety inthe Republic ofCroatia in 1995 as compared to the year1994indicates a slight decrease in the number of injuries and fatalinjuries sustained in road traffic accidents, in the incidence ofaccidents with injuries and incidence of accidents in general,despite the reported increase in motor fuel sales and active integrationof a substantial segment of the road system in the Republicof Croatia.Regardless of the causes of road traffic accidents, relevantfactors of influence, types of road traffic accidents, locations,vehicle structure and technical functioning status, and circumstancesof accidents, it is indisputable that the years of servicei.e. experience (or better, non-experience of drivers appear tobe of major impact upon the number of accidents. Of 62,120road traffic accidents in 1994, 44.4% of accidents resultingfrom driver error were caused by drivers having up to threeyears of driving experience, making 42.9% of all accidents.This fact is both logical and notorious, applying not only tothe Republic of Croatia but to most European countries. Themethods and activities taken to change these figures (effecttheir decrease differ.

  19. The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

    DEFF Research Database (Denmark)

    Hansson Petersen, Camilla A; Alikhani, Nyosha; Behbahani, Homira

    2008-01-01

    that extracellulary applied Abeta can be internalized by human neuroblastoma cells and can colocalize with mitochondrial markers. Together, these results provide further insight into the mitochondrial uptake of Abeta, a peptide considered to be of major significance in Alzheimer's disease....

  20. Radiation physics of non-metallic crystals. Volume III, No. 3. Radiatsionnaya fizika nemetallicheskikh kristallov. Tom III, Chast 3

    Energy Technology Data Exchange (ETDEWEB)

    Konozenko, I D [ed.

    1971-01-01

    Separate articles are presented on studies concerned with radiation phenomena in ionic crystals and dielectrics. Topics include energy losses and electron escape in monocrystals, non-stationary acoustic absorption in monocrystals, charge behavior in radioactive dielectrics, the effects of electron radiation on the electroconductivity of organic dielectrics, adsorption of polyatomic gases in adsorbents, catalysis and inhibition of solid inorganic salt radiolysis, and the formation of additive paramagnetic centers in gamma radiated salts of alkaline earth metals. 253 references.

  1. Current Direction and Velocity Measurements Using GPS Receivers Mounted on Floats at Tom Bevill Lock and Dam

    Science.gov (United States)

    2002-12-01

    radio and batteries. The procedures outlined in this CHETN will concentrate on the Magellan GPS ProMARK X-CP receiver as it was used to collect...The Magellan GPS ProMARK X-CP is a small robust light receiver that can log 9 hr of both pseudorange and carrier phase satellite data for post...post- processing software, pseudorange GPS data recorded by the ProMARK X-CP can be post-processed differential to achieve 1-3 m (3.3-9.8 ft) horizontal

  2. Materie a nemateriální substance podle Bonaventury a Tomáše Akvinského

    Czech Academy of Sciences Publication Activity Database

    Machula, Tomáš

    2009-01-01

    Roč. 57, č. 2 (2009), s. 209-220 ISSN 0015-1831 Institutional research plan: CEZ:AV0Z90090514 Keywords : Aquinas * Bonaventure * matter * immaterial substances Subject RIV: AA - Philosophy ; Religion

  3. CERES AuTomAted job Loading SYSTem (CATALYST): An automated workflow manager for satellite data production

    Science.gov (United States)

    Gleason, J. L.; Hillyer, T. N.; Wilkins, J.

    2012-12-01

    The CERES Science Team integrates data from 5 CERES instruments onboard the Terra, Aqua and NPP missions. The processing chain fuses CERES observations with data from 19 other unique sources. The addition of CERES Flight Model 5 (FM5) onboard NPP, coupled with ground processing system upgrades further emphasizes the need for an automated job-submission utility to manage multiple processing streams concurrently. The operator-driven, legacy-processing approach relied on manually staging data from magnetic tape to limited spinning disk attached to a shared memory architecture system. The migration of CERES production code to a distributed, cluster computing environment with approximately one petabyte of spinning disk containing all precursor input data products facilitates the development of a CERES-specific, automated workflow manager. In the cluster environment, I/O is the primary system resource in contention across jobs. Therefore, system load can be maximized with a throttling workload manager. This poster discusses a Java and Perl implementation of an automated job management tool tailored for CERES processing.

  4. Major Tom to Ground Control: How Lipoproteins Communicate Extracytoplasmic Stress to the Decision Center of the Cell.

    Science.gov (United States)

    Laloux, Géraldine; Collet, Jean-François

    2017-11-01

    The envelope of bacteria is a complex multilayered shield that ensures multiple essential functions, including protecting the cell from external assaults. Hence, bacterial cells have evolved intricate mechanisms called envelope stress response systems (ESRS) to monitor all kinds of perturbations affecting the integrity of their envelope and to mount an appropriate response to contain or repair the damage. In the model bacterium Escherichia coli , several ESRS are built around a two-component system, in which envelope stress triggers a phosphotransfer between a sensor protein in the inner membrane of the envelope and a response regulator in the cytoplasm. In this review, we focus on two major ESRS in E. coli , the Rcs and Cpx pathways, in which additional proteins not directly involved in the phosphotransfer modulate signal transduction. Both the Rcs and Cpx systems can be turned on by a lipoprotein anchored in the outer membrane, RcsF and NlpE, respectively, providing a molecular connection between the most exterior layer of the envelope and the ground control center in the cytoplasm. Here, we review how these two lipoproteins, which share a striking set of features while being distinct in several aspects, act as sentinels at the front line of the bacterium by sensing and transducing stress to the downstream components of the Rcs and Cpx systems. Copyright © 2017 American Society for Microbiology.

  5. Töötajad hoolitsevad ise otstarbeka ajakasutuse eest / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2007-01-01

    Ilmunud ka: Delovõje Vedomosti 28. nov. lk. 38. Andes töötajatele vabaduse ise otsustada oma tööaja üle, paranevad nende töö efektiivsus ning ettevõtte majandustulemused. Lisa: Paindlik tööaeg toob kasu. Kommenteerib Aneta Jajkowska

  6. Emotion and Emotionality as a Hidden Dimension of Lexicon and Discourse

    Science.gov (United States)

    Viberg, Ake

    2008-01-01

    In her thought-provoking article, Aneta Pavlenko approaches emotion and emotion-laden words in the bilingual lexicon from an impressive number of different perspectives. This is particularly welcome, since most models of linguistic structure do not account for emotional meanings in a systematic way. One exception worth mentioning, however, is…

  7. Biotransformation of selected anthelmintics in sheep tapeworm (Moniezia expansa)

    OpenAIRE

    Bečanová, Aneta

    2013-01-01

    Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Aneta Bečanová Supervisor: Mgr. Hana Bártíková, Ph.D. Title of diploma thesis: Biotransformation of selected anthelmintics in sheep tapeworm (Moniezia expansa) Biotransformation of anthelmintics is a process that prevents the parasite from adverse effects of xenobiotics. Therefore, it is the main factor that causes the reduction of an anthelmintic effect, resistance development and...

  8. Spiritualita uživatelů marihuany

    OpenAIRE

    Bučková, Aneta

    2014-01-01

    TITLE: Marijuana users spirituality AUTHOR: Aneta Bučková DEPARTMENT: Department of psychology SUPERVISOR: Mgr. Radovan Hrubý ABSTRACT: The theme of this thesis is spirituality of the marihuana users. The first part of the thesis focuses on the problematic of definition of spirituality. Furthermore, spirituality is put in historical and cultural context of use of psychotropic substances and finally in context of actual researches and approaches. The goal of the research part is to determine w...

  9. Víra jako sociální opora

    OpenAIRE

    Holečková, Žaneta

    2016-01-01

    Name and Suriname of the autor: Žaneta Holečková Institution: Charles University in Prague, Faculty of Medicine in Hradec Králové, Department of Social Medicine, Department of Nursing Title: Faith es social support Supervisor: Mgr. Michaela Votroubková Number of pages: 59 Number of attachments: 6 Year of defense: 2016 Keywords: faith, social support, Christianity, religion, nursing, disease, patient Summary: This bachelor's thesis represents Christian faith in terms of social support. It is s...

  10. Robert J. Flaherty and Seáinín Tom Ó Dioráin: Lights, Camera, and (Not Too Much Action

    Directory of Open Access Journals (Sweden)

    Tomás Ó h-Íde (Ihde

    2016-03-01

    Full Text Available Famed director Robert Flaherty’s first direct sound film, Oidhche Sheanchais, was recently discovered at Harvard University. This article discusses the impact that the discovery will have on our understanding of this short film, especially as concerns film studies and folklore. It notes several misunderstandings reported in the literature over the years that have now been set right with the finding of the film. The article points to resources held in archives in Ireland and the United States that can additionally address questions related to this film. While a noteworthy contribution to the filmography of Robert Flaherty, the short ‘talkie’ must be approached with caution by folklorists due to the coaching of actors and cinematographic editing.

  11. Sentarse a la mesa del Señor. Metaforizaciones y conflictos en La última cena de Tomás Gutiérrez Alea

    Directory of Open Access Journals (Sweden)

    Flavio Fiorani

    2011-11-01

    Full Text Available La última cena by Gutiérrez Alea is based on an actual event that took place in Cuba: one Holy Thursday at the end of the Eighteen century the owner of a sugar plantation invites twelve of his slaves to dinner and shows them the path to salvation through the message of Christian Redemption. In particular, the film shows how during the Easter rite the messianic event and the metaphoric language of salvation lead to shifts in meaning that the slaves interpret as the concrete possibility for them to be free. The sacred of the liturgical act as an “action” that can be performed by the guests at the Lord’s table in order to reach freedom is reproduced by the very cinematographic language. Actually, the slaves oppose to the Christian account an “open word”, thus debunking the project of disciplining them and stirring a rebellion in which the contamination of the sacred with the profane becomes the epiphany of a new life: no more a celestial one, but a worldly and free life in the isle of Cuba.

  12. Sant Tomàs Becket i el programa iconogràfic de les pintures murals de Santa Maria de Terrassa

    OpenAIRE

    Guàrdia, Milagros

    1998-01-01

    L'anàlisi del programa iconogràfic de les pintures romàniques de Terrassa parteix de la filiació d'una de les escenes més rellevants, la mort de Becket, respecte dels models establerts a la catedral de Canterbury en les dues darreres dècades del segle XII i dels tituli que es traslladen a les inscripcions pintades a Santa Maria. S'intenta una interpretació del conjunt tot proposant la identificació de sant Esteve com a referència al darrer dels màrtirs en la conca de l'absis, així com a l'est...

  13. Ungaretti tradutor discreto e a analogia entre os poetas árcades Tomás Antônio Gonzaga e Giovanni Meli

    Directory of Open Access Journals (Sweden)

    Lucia Wataghin

    2003-07-01

    Full Text Available Será apresentada e discutida a interessante analogia, sugerida por Giuseppe Ungaretti, entre a poesia de T.A. Gonzaga e a poesia em dialeto siciliano de um outro árcade, Giovanni Meli, seu contemporâneo. Em seguida, a partir das traduções realizadas por G. Ungaretti (1946. G. Vegezzi-Ruscalla (1844, E. de Monglave e P. Chalas (1825 da lira Tu não verás, Marília..., de T.A. Gonzaga, serão comentados aspectos do poema e de sua recepção em épocas e países diferentes.

  14. Aproximaciones al exilio de Tomás Segovia a través de la “fidelidad” de Goethe, Cesare Pavese y Albert Camus

    NARCIS (Netherlands)

    Houvenaghel, E.M.H.

    2014-01-01

    México 2011). Para ello, recurrimos a la noción de ‘fidelidad’ ya que Segovia considera el destierro una ‘experiencia de fidelidad-infidelidad’. Con el fin de llegar al mejor entendimiento de los orígenes del concepto de ‘fidelidad’ nos remontamos a sus ensayos de los años 50 y 60 (Sextante 1991) en

  15. Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

    DEFF Research Database (Denmark)

    Medina-Gomez, Carolina; Kemp, John P; Dimou, Niki L

    2017-01-01

    Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS meta-analysis of total-body lean mass (TB-LM) and total-body less head bone...... as in human muscle tissue. This is the first bivariate GWAS meta-analysis to demonstrate genetic factors with pleiotropic effects on bone mineral density and lean mass.Bone mineral density and lean skeletal mass are heritable traits. Here, Medina-Gomez and colleagues perform bivariate GWAS analyses of total...

  16. Innovación del gobierno colombiano para el sector minero energético Tomás González

    Directory of Open Access Journals (Sweden)

    Tomás González

    2011-01-01

    Full Text Available En Colombia es evidente la necesidad de innovar en el sector público. En este artículo se presenta el caso específico de la innovación del gobierno en el sector minero. Para esto, se iniciará con la identificación del potencial minero en Colombia y las barreras para su explotación. En seguida se explorarán los planes de innovación del gobierno como una estrategia para sobrepasar aquellas barreras que impiden aprovechar este potencial.//The need to innovate the public sector in Colombia is evident. This article presents the specific case of governmental innovation within the mining sector. It begins with the identification of mining potential in Colombia and the barriers that impede its exploitation. It is concluded by exploring governmental innovation plans that seek to overcome those barriers to take full advantage of Colombia's potential.

  17. Una nueva mirada sobre Rafael del Olmo, a partir de los papeles de Torner conservados en la Biblioteca Tomas Navarro Tomás del CSIC (Madrid

    Directory of Open Access Journals (Sweden)

    Cristina Martí Martínez

    2014-01-01

    Estas partituras se presentan en este texto. Sin profundizar en todo su contenido, sí se dará noticia del nexo común a todas ellas: el compositor, de origen cordobés y malagueño de adopción, Rafael del Olmo y Bueno (1826-, que copió la mayoría de las piezas y de cuya breve obra nos ha llegado una zarzuela, algunos arreglos y varios villancicos para coro y banda con poesías del dramaturgo Ramón Franquelo Martínez (1824-1874.

  18. Tom Sawyer tahab päästa neegri, kuid jääb Draamateatri laval jänni / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2010-01-01

    Eesti Draamateatris 10. oktoobril 2010 esietendunud A. Kivirähk'i Mark Twaini teoste ainetel valminud uuest näidendist "Neegri vabastamine kõrgel kunstilisel tasemel", lavastaja Hendrik Toompere jr.

  19. THE GENUS MIMOSA WITH SPECIAL REFERENCE TOM. QUADRIVALVIS L. VAR. LEPTOCARPA (D.C. EARNEDY, A NEW SPECIES RECORD FOR THE WEED FLORA IN MALAYSIA

    Directory of Open Access Journals (Sweden)

    BAKI, B. BAKAR

    1996-01-01

    Full Text Available An exploratory floristic survey of the genus Mimosa was conducted in 1993 to ascertain species diversity and their spatial patterns of distribution in Peninsular Malaysia. A new species record of uncertain indigene, M.. quadrivalvis was recorded for the first time in restricted localities along the roadsides in Pekan Darat and Bertam, Seberang Perai, Gurun and Bedong in Kedah in addition to widely distributed and seemingly ubiquitous presence of M. invisa Mart. ex. Colla and M. pudica L. The latter two species were mostly found in open, disturbed and derelict habitats, agricultural areas and ex-mining lands. Both species exhibited largely contagious and overdispersed distribution patterns with positive peaks in pattern intensity values although regularity or underdispersed distribution patterns do manifest in certain localities. The giant mimosa, M. pigra inhabited in clustered thickets, large pockets of lands in the urban and sub-urban localities in the states of Penang, Perak, Kelantan, Kuala Lumpur and Negeri Sembilan. In other states, M. pigra was confined to a few localities in smaller patches. Except for M. quadrivalvis, the other species of Mimosa are serious weeds in the agricultural, recreational and residential and derelict areas. A key to the Mimosa species is constructed along with brief descriptions on their morphology and ecology.

  20. RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials.

    Science.gov (United States)

    Oronsky, Bryan; Paulmurugan, Ramasamy; Foygel, Kira; Scicinski, Jan; Knox, Susan J; Peehl, Donna; Zhao, Hongjuan; Ning, Shoucheng; Cabrales, Pedro; Summers, Thomas A; Reid, Tony R; Fitch, William L; Kim, Michelle M; Trepel, Jane B; Lee, Min-Jung; Kesari, Santosh; Abrouk, Nacer D; Day, Regina M; Oronsky, Arnold; Ray, Carolyn M; Carter, Corey A

    2017-01-01

    According to Hanahan and Weinberg, cancer manifests as six essential physiologic hallmarks: (1) self-sufficiency in growth signals, (2) insensitivity to growth-inhibitory signals, (3) evasion of programmed cell death, (4) limitless replicative potential, (5) sustained angiogenesis, and (6) invasion and metastasis. As a facilitator of these traits as well as immunosuppression and chemoresistance, the presence of tumor-associated macrophages (TAMs) may serve as the seventh hallmark of cancer. Anticancer agents that successfully reprogram TAMs to target rather than support tumor cells may hold the key to better therapeutic outcomes. Areas covered: This article summarizes the characteristics of the macrophage-stimulating agent RRx-001, a molecular iconoclast, sourced from the aerospace industry, with a particular emphasis on the cell-to-cell transfer mechanism of action (RBCs to TAMs) underlying its antitumor activity as well as its chemo and radioprotective properties, consolidated from various preclinical and clinical studies. Expert opinion: RRx-001 is macrophage-stimulating agent with the potential to synergize with chemotherapy, radiotherapy and immunotherapy while simultaneously protecting normal tissues from their cytotoxic effects. Given the promising indications of activity in multiple tumor types and these normal tissue protective properties, RRx-001 may be used to treat a broad spectrum of malignancies, if it is approved in the future.

  1. Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice.

    Science.gov (United States)

    Penas, Federico; Mirkin, Gerardo A; Vera, Marcela; Cevey, Ágata; González, Cintia D; Gómez, Marisa I; Sales, María Elena; Goren, Nora B

    2015-05-01

    Trypanosoma cruzi, the etiological agent of Chagas' disease, induces a persistent inflammatory response. Macrophages are a first line cell phenotype involved in the clearance of infection. Upon parasite uptake, these cells increase inflammatory mediators like NO, TNF-α, IL-1β and IL-6, leading to parasite killing. Although desired, inflammatory response perpetuation and exacerbation may lead to tissue damage. Peroxisome proliferator-activated receptors (PPARs) are ligand-dependent nuclear transcription factors that, besides regulating lipid and carbohydrate metabolism, have a significant anti-inflammatory effect. This is mediated through the interaction of the receptors with their ligands. PPARγ, one of the PPAR isoforms, has been implicated in macrophage polarization from M1, the classically activated phenotype, to M2, the alternatively activated phenotype, in different models of metabolic disorders and infection. In this study, we show for the first time that, besides PPARγ, PPARα is also involved in the in vitro polarization of macrophages isolated from T. cruzi-infected mice. Polarization was evidenced by a decrease in the expression of NOS2 and proinflammatory cytokines and the increase in M2 markers like Arginase I, Ym1, mannose receptor and TGF-β. Besides, macrophage phagocytic activity was significantly enhanced, leading to increased parasite load. We suggest that modulation of the inflammatory response by both PPARs might be due, at least in part, to a change in the profile of inflammatory macrophages. The potential use of PPAR agonists as modulators of overt inflammatory response during the course of Chagas' disease deserves further investigation. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Glycine-rich loop of mitochondrial processing peptidase α-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20

    Czech Academy of Sciences Publication Activity Database

    Dvořáková-Holá, Klára; Matušková, Anna; Kubala, M.; Otyepka, M.; Kučera, Tomáš; Večeř, J.; Heřman, P.; Parkhomenko, Natalia; Kutejová, E.; Janata, Jiří

    2010-01-01

    Roč. 396, č. 5 (2010), s. 1197-1210 ISSN 0022-2836 R&D Projects: GA AV ČR IAA501110631 Institutional research plan: CEZ:AV0Z50200510 Keywords : mitochondrial processing peptidase * presequence * substrate recognition Subject RIV: EE - Microbiology, Virology Impact factor: 4.008, year: 2010

  3. Wittgenstein a privátnosti pocitů. Odpověď Tomáši Čanovi

    Czech Academy of Sciences Publication Activity Database

    Koťátko, Petr

    2015-01-01

    Roč. 63, č. 3 (2015), s. 459-462 ISSN 0015-1831 Institutional support: RVO:67985955 Keywords : utterance meaning * communicative intentions * linguistic conventions * privacy * mental states * feelings Subject RIV: AA - Philosophy ; Religion

  4. O tom, co vidíme v mlze. Fenomenologická esej o nepředstavitelnosti nelidského

    Czech Academy of Sciences Publication Activity Database

    Nitsche, Martin

    2014-01-01

    Roč. 69, č. 7 (2014), s. 604-612 ISSN 0046-385X R&D Projects: GA ČR(CZ) GA14-22586S Institutional support: RVO:67985955 Keywords : phenomenological topology * imagination * unrepresentability * non-human Subject RIV: AA - Philosophy ; Religion

  5. Czech(-oslovak) National Commemorations during the Interwar Period: Tomáš G. Masaryk and the Battle of White Mountain Avenged

    Czech Academy of Sciences Publication Activity Database

    Hájková, Dagmara; Wingfield, N.

    2010-01-01

    Roč. 18, č. 3 (2010), s. 425-452 ISSN 1318-0185 Institutional research plan: CEZ:AV0Z70900502 Keywords : Masaryk, T. G. * national identity * Czechoslovakia, history Subject RIV: AB - History Impact factor: 0.108, year: 2010

  6. Princip individuace materiálních jsoucen v díle Tomáše Akvinského

    Czech Academy of Sciences Publication Activity Database

    Svoboda, David

    2010-01-01

    Roč. 12, č. 39 (2010), s. 21-37 ISSN 1212-8570 R&D Projects: GA AV ČR(CZ) IAA900090802 Institutional research plan: CEZ:AV0Z90090514 Keywords : Aquinas * individuation * substance * accident Subject RIV: AA - Philosophy ; Religion

  7. Wave activity (planetary, tidal) throughout the middle atmosphere (20-100km) over the CUJO network: Satellite (TOMS) and Medium Frequency (MF) radar observations

    OpenAIRE

    A. H. Manson; C. E. Meek; T. Chshyolkova; S. K. Avery; D. Thorsen; J. W. MacDougall; W. Hocking; Y. Murayama; K. Igarashi

    2005-01-01

    Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT) is studied using combinations of ground-based (GB) and satellite instruments (2000-2002). The relatively new MFR (medium frequency radar) at Platteville (40° N, 105° W) has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opp...

  8. DISCOURSE AND THIRD SPACE IN FRANK MCCOURT’S NOVEL "TEACHER MAN" AND TOM SCHULMAN’S PLAY "DEAD POETS SOCIETY"; A REFLECTIVE PRACTICE FOR TEACHERS

    Directory of Open Access Journals (Sweden)

    Eka Sugeng Ariadi

    2017-08-01

    Full Text Available Pahl and Rowsell (2005 elucidate that Discourse is ways of dressing, speaking and acting which delineates person’s identities in literacy practices, while a third space is as a meeting spaces between home space and school space, blend and mix space, in which lets teachers think how their students’ meaning-making are happened between school and home. This paper investigates how these theories are fruitfully presented in the character of Mr. McCourt Teacher Man and Mr. Keating Dead Poets Society. Subsequently, it is interconnected with educational theory A taxonomy for Learning, teaching, and assessing: A revision of Bloom’s taxonomy of educational objectives, as recommended by Anderson and Krathwohl (2001. The result shows that the Metacognitive Knowledge domain prominently becomes the intersection as it is emphasizing on the student’s awareness of one’s own cognition and cognitive processes, particularly contextualizing students’ knowledge and general knowledge. Mr. McCourt and Mr. Keating have succeeded in shifting frighten and strict classroom situation generated by most teachers become so challenging and much interesting by utilizing multimodal styles and skills, and piloting third space activity. Henceforth, the writer recommends teachers to maximize their own potentials characters to accommodate their students’ preferences or styles in learning the subjects. In addition, designing teaching and learning process in-between home and school is necessary to be done, in order to contextualizing and perceiving real life experiences.

  9. Modelos para el diseño de experiencias transmedia en entornos educativos. Exploraciones en torno a The Walking Dead, La Odisea y Tom Sawyer

    Directory of Open Access Journals (Sweden)

    Diego MONTOYA-BERMÚDEZ

    2018-01-01

    Full Text Available Este texto presenta dos modelos para el diseño de experiencias transmediales aplicables desde el contexto de la comunicación a escenarios pedagógicos. Usando como método la investigación a través del diseño, se sistematizan dos prácticas de transmediación: una de carácter narrativo en contextos educativos formales, y la otra experiencial para entornos pedagógicos informales; ambos ejercicios con fines comunes: incentivar la lectura y la escritura en distintos públicos, y potenciar las prácticas transmedia como dinamizadores de procesos de alfabetización mediática, en una idea de poner los medios de comunicación del lado de la educación. Dichas propuestas permitieron evidenciar, tanto desde los sistemas intertextuales como desde los intermediales, las potencialidades de la transmedialidad como vector articulador de procesos de creación y experimentación. Finalmente, como aporte, el texto se centra en la elaboración de una propuesta metodológica para el diseño transmedia de experiencias mediante la cual se plantea la intermedialidad como una mirada más amplia hacia la transmediación.

  10. Neural processing of emotional facial and semantic expressions in euthymic bipolar disorder (BD and its association with theory of mind (ToM.

    Directory of Open Access Journals (Sweden)

    Agustin Ibanez

    Full Text Available BACKGROUND: Adults with bipolar disorder (BD have cognitive impairments that affect face processing and social cognition. However, it remains unknown whether these deficits in euthymic BD have impaired brain markers of emotional processing. METHODOLOGY/PRINCIPAL FINDINGS: We recruited twenty six participants, 13 controls subjects with an equal number of euthymic BD participants. We used an event-related potential (ERP assessment of a dual valence task (DVT, in which faces (angry and happy, words (pleasant and unpleasant, and face-word simultaneous combinations are presented to test the effects of the stimulus type (face vs word and valence (positive vs. negative. All participants received clinical, neuropsychological and social cognition evaluations. ERP analysis revealed that both groups showed N170 modulation of stimulus type effects (face > word. BD patients exhibited reduced and enhanced N170 to facial and semantic valence, respectively. The neural source estimation of N170 was a posterior section of the fusiform gyrus (FG, including the face fusiform area (FFA. Neural generators of N170 for faces (FG and FFA were reduced in BD. In these patients, N170 modulation was associated with social cognition (theory of mind. CONCLUSIONS/SIGNIFICANCE: This is the first report of euthymic BD exhibiting abnormal N170 emotional discrimination associated with theory of mind impairments.

  11. Neural processing of emotional facial and semantic expressions in euthymic bipolar disorder (BD) and its association with theory of mind (ToM).

    Science.gov (United States)

    Ibanez, Agustin; Urquina, Hugo; Petroni, Agustín; Baez, Sandra; Lopez, Vladimir; do Nascimento, Micaela; Herrera, Eduar; Guex, Raphael; Hurtado, Esteban; Blenkmann, Alejandro; Beltrachini, Leandro; Gelormini, Carlos; Sigman, Mariano; Lischinsky, Alicia; Torralva, Teresa; Torrente, Fernando; Cetkovich, Marcelo; Manes, Facundo

    2012-01-01

    Adults with bipolar disorder (BD) have cognitive impairments that affect face processing and social cognition. However, it remains unknown whether these deficits in euthymic BD have impaired brain markers of emotional processing. We recruited twenty six participants, 13 controls subjects with an equal number of euthymic BD participants. We used an event-related potential (ERP) assessment of a dual valence task (DVT), in which faces (angry and happy), words (pleasant and unpleasant), and face-word simultaneous combinations are presented to test the effects of the stimulus type (face vs word) and valence (positive vs. negative). All participants received clinical, neuropsychological and social cognition evaluations. ERP analysis revealed that both groups showed N170 modulation of stimulus type effects (face > word). BD patients exhibited reduced and enhanced N170 to facial and semantic valence, respectively. The neural source estimation of N170 was a posterior section of the fusiform gyrus (FG), including the face fusiform area (FFA). Neural generators of N170 for faces (FG and FFA) were reduced in BD. In these patients, N170 modulation was associated with social cognition (theory of mind). This is the first report of euthymic BD exhibiting abnormal N170 emotional discrimination associated with theory of mind impairments.

  12. Medical therapy versus radiofrequency endometrial ablation in the initial treatment of heavy menstrual bleeding (iTOM Trial: A clinical and economic analysis.

    Directory of Open Access Journals (Sweden)

    Abimbola O Famuyide

    Full Text Available Radiofrequency endometrial ablation (REA is currently a second line treatment in women with heavy menstrual bleeding (MHB if medical therapy (MTP is contraindicated or unsatisfactory. Our objective is to compare the effectiveness and cost burden of MTP and REA in the initial treatment of HMB.We performed a randomized trial at Mayo Clinic Rochester, Minnesota. The planned sample size was 60 patients per arm. A total of 67 women with HMB were randomly allocated to receive oral contraceptive pills (Nordette ® or Naproxen (Naprosyn® (n = 33 or REA (n = 34. Primary 12-month outcome measures included menstrual blood loss using pictorial blood loss assessment chart (PBLAC, patients' satisfaction, and Menorrhagia Multi-Attribute Scale (MMAS. Secondary outcomes were total costs including direct medical and indirect costs associated with healthcare use, patient out-of-pocket costs, and lost work days and activity limitations over 12 months.Compared to MTP arm, women who received REA had a significantly lower PBLAC score (median [Interquartile range, IQR]: 0 [0-4] vs. 15 [0-131], p = 0.003, higher satisfaction rates (96.8%vs.63.2%, p = 0.003 and higher MMAS (median [IQR]: 100 [100-100] vs. 100 [87-100], p = 0.12 at 12 months. Direct medical costs were higher for REA ($5,331vs.$2,901, 95% confidence interval (CI of mean difference:$727,$4,852, however, when indirect costs are included, the difference did not reach statistical significance ($5,469 vs. $3,869, 95% CI of mean difference:-$339, $4,089.For women with heavy menstrual bleeding, initial radiofrequency endometrial ablation compared to medical therapy offered superior reduction in menstrual blood loss and improvement in quality of life without significant differences in total costs of care.NCT01165307.

  13. Relationship between the mothers' nutritional status with that of a child population from São Tomé Principe, "Africa"

    Directory of Open Access Journals (Sweden)

    Diana e Silva

    Full Text Available Abstract Objectives: analyse the relation between the nutritional status of children with 0 to 60 months in São Tome and Principe (STP and their mothers. Methods: characterization of the nutritional status of 1,169 children for the weight / length ratio (W/L (≤24months and Body Mass Index (BMI for age (>24months and their mothers. The Chi Square or Fisher tests were used for the study on the relation between the nutritional status of the mother and children, as appropriate. Results: fifty-five percent (55% of the children are female (median = 21 months. There was a high percentage of global acute malnutrition in the children aged0≤24months (30.2% and 24≤60months (22% as well as global chronic malnutrition (32% and 41.1% respectively. We observed a high percentage of overweight /obese mothers (31.6%, with 16.5% of them being of a low height. We observed a significantly higher percentage of children with global acute malnutrition 47.5% when compared with that which was reported for children of normal mothers (27.9% or overweight /obese (22% (p<0,001 mothers. Conclusions: It was observed a high prevalence of acute and chronic global malnutrition in the children studied and a high prevalence of overweight /obese mothers. We observed a statistically significant association between maternal and acute global malnutrition of the children.

  14. Caracterización del perfil de los estudiantes de Negocios Internacionales de la Universidad Santo Tomás, sede Bogotá

    OpenAIRE

    Myriam Soraya Suárez R.; Ana María Jiménez C.

    2013-01-01

    Los estudios sobre el perfil de los estudiantes universitarios se han llevado a cabo permanentemente, debido a que las universidades requieren saber con qué estudiantes cuentan y cómo estos requieren ser formados, de acuerdo con las necesidades actua - les del mercado laboral y las necesidades sociales del contexto en el cual se encuentran inmersos. Esta investigación sobre la caracterización del perfil de los estudiantes de la Facultad de Negocios Internacionales de la Universidad Santo...

  15. BOOK REVIEW: ADRENALINE JUNKIES AND TEMPLATE ZOMBIES Understanding Patterns of Project Behavior by Tom Demarco, Peter Hruschka, Tim Lister, Steve McMenamin, James Robertson, Suzanne Robertson

    Directory of Open Access Journals (Sweden)

    DR. KADIR ALPASLAN DEMIR

    2016-10-01

    Full Text Available Today, armed forces are in continuous transformation. As new technologies are developed and new principles of war are introduced, the ministries of defenses and armed forces have to adapt to this changing environment. Almost every day, military officials start new projects to handle the technological and cultural transformations in the military. Project management became an integral part of defense development and management. Today, all high or middle level military officials are either a project sponsor overseeing a project, or a project manager executing a project, or a member of project team helping the project to become a reality. As a result, project management skills became an essential part of skillset that a military official need to successfully execute his/her duties.

  16. Comparison of ultraviolet Bi-directional Reflectance Distribution Function (BRDF) measurements of diffusers used in the calibration of the Total Ozone Mapping Spectrometer (TOMS)

    NARCIS (Netherlands)

    Butler, J.J.; Park, H.; Barnes, P.Y.; Early, E.A.; Eijk-Olij, C. van; Zoutman, A.E.; Buller-Leeuwen, S. van; Groote Schaarsberg, J.

    2002-01-01

    The measurement and long-term monitoring of global total ozone by ultraviolet albedo measuring satellite instruments require accurate and precise determination of the Bi-directional Reflectance Distribution Function (BRDF) of laboratory-based diffusers used in the pre-launch calibration of those

  17. Comparison of ultraviolet Bi-directional Reflectance Distribution Function (BRDF) measurements of diffusers used in the calibration of the Total Ozone Mapping Spectrometer (TOMS)

    OpenAIRE

    Butler, J.J.; Park, H.; Barnes, P.Y.; Early, E.A.; Eijk-Olij, C. van; Zoutman, A.E.; Buller-Leeuwen, S. van; Groote Schaarsberg, J.

    2002-01-01

    The measurement and long-term monitoring of global total ozone by ultraviolet albedo measuring satellite instruments require accurate and precise determination of the Bi-directional Reflectance Distribution Function (BRDF) of laboratory-based diffusers used in the pre-launch calibration of those instruments. To assess the ability of laboratories to provide accurate Ultra Violet (UV) diffuse BRDF measurements, a BRDF measurement comparison was initiated by the NASA Total Ozone Mapping Spectrom...

  18. A simplified method for the thermal design of buildings in overseas departments; Methode simplifiee pour la conception thermique du batiment dans les DOM-TOM

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    The main principles of climate (more especially tropical climate), thermal comfort and thermal architectural design are first reviewed, with emphasis on wall, roof and window heat transfers and natural and artificial air conditioning in tropical houses and buildings, with the objective of minimizing energy consumption and maximizing thermal comfort. Meteorological data and calculation diagrams are given for site and orientation optimization and building envelope dimensioning and design in tropical zones (example of New Caledonia)

  19. Dopis brabantské vévodkyni Tomáše Akvinského a jeho recepce v Knížkách šesterých o obecných věcech křesťanských Tomáše ze Štítného

    Czech Academy of Sciences Publication Activity Database

    Blažek, Pavel

    2016-01-01

    Roč. 8, č. 2 (2016), s. 247-258 ISSN 1804-0977 EU Projects: European Commission(XE) 263672 - OVERMODE Institutional support: RVO:67985955 Keywords : Jews * usury * taxes * reception of Latin literature * medieval religious and didactic literature * vernacularisation Subject RIV: AA - Philosophy ; Religion OBOR OECD: Philosophy, History and Philosophy of science and technology

  20. De los deseos de Peralta al deseo inconsciente (Lo cómico y el chiste en un cuento de Tomás Carrasquilla. // from Peralta`s desire to unconscious desire (The comic and the joke in a short story by Tomás Carrasquilla.

    Directory of Open Access Journals (Sweden)

    Juan Ricardo Gallo

    2010-06-01

    Full Text Available Literature and, in this case, an “Antioquenian popular short story” tackle the elusiveness of truth from a comic perspective. The short story titled En la Diestra de Dios Padre (To the Right Hand of Father God is well known for being a funny story. Its very author defined it as a complex short story with deep theological and religious features. Its comic references reveal a deeper and more fundamental truth about human life. The paradox is that the comic is a semi-tell that saves the effort of intellection by laughing, but keeping the sense, not only of the content, but especially also the effort saved. This is, in other words, a brief technique to express a repressed truth. // La literatura, y en este caso un "cuento popular antioqueño", abordan lo esquivo de la verdad desde el ángulo cómico. El cuento En la diestra de Dios Padre es reconocido por lo chistoso. El mismo Tomas Carrasquilla lo definió como un complejo cuento de características teológico religiosas profundas. Es como si lo cómico que hay en él dejara traslucir verdades más profundas, más esenciales, de la vida humana. Lo paradójico es que lo cómico es un semidecir, ahorra el esfuerzo de la intelección a través de la risa, pero manteniendo el sentido no solo de lo contenido sino, en particular, del esfuerzo ahorrado. Es, para decirlo de otra manera, una técnica abreviada de evidenciar la verdad reprimida.

  1. Unique Theory of Mind Differentiation in Children with Autism and Asperger Syndrome

    OpenAIRE

    Tine, Michele; Lucariello, Joan

    2012-01-01

    This study was designed to determine if ToM abilities of children with autism and Asperger syndrome differentiate into Intrapersonal ToM and Social ToM. A battery of Social and Intrapersonal ToM tasks was administered to 39 children with autism and 34 children with Asperger syndrome. For both groups of children, ToM differentiated and Intrapersonal ToM was stronger than Social ToM. This asymmetry was greater for children with autism, whose Social ToM was especially weak. These results support...

  2. Kwalifikacje i kompetencje trenerów personalnych a oczekiwania rynku pracy = Personal trainers professional qualifications - demands of the labour market

    OpenAIRE

    Leśniewska, Aleksandra; Stosik, Aneta

    2016-01-01

    Leśniewska Aleksandra, Stosik Aneta. Kwalifikacje i kompetencje trenerów personalnych a oczekiwania rynku pracy = Personal trainers professional qualifications - demands of the labour market. Journal of Education, Health and Sport. 2016;6(9):25-35. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.61707 http://www.ojs.ukw.edu.pl/index.php/johs/article/view/3831 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B ...

  3. History and the present of women football in the Czech Republic (Czechoslovakia)

    OpenAIRE

    Dědinová, Aneta

    2017-01-01

    Title of bachelor thesis: History and the present of organized woman's football in the Czech Republic/ Czechoslovakia Processed by: Aneta Dědinová Head of Bachelor Thesis: Doc. PhDr. Irena Slepičková, CSc. Aims of the work: Mapping the development and the current form of fiale football in the Czech Republic (hereinafter only the Czech Republic) in clubs and on a global scale. To find out how the situation in female football is perceived by representatives of local clubs and people working in ...

  4. Několik poznámek k filosofickým důkazům existence separovaných substancí u Tomáše Akvinského

    Czech Academy of Sciences Publication Activity Database

    Jindráček, Efrem

    2012-01-01

    Roč. 4, č. 7 (2012), s. 105-114 ISSN 1803-7860 Institutional support: RVO:67985955 Keywords : Thomas Aquinas * separate substances * philosophical argument for existence * demon * angel Subject RIV: AA - Philosophy ; Religion

  5. Augustiniánská knihovna u sv. Tomáše v Praze. II. část: Období reformace a protireformace (do konce 17. století)

    Czech Academy of Sciences Publication Activity Database

    Sladká, Veronika

    2017-01-01

    Roč. 24, 1/2 (2017), s. 29-66 ISSN 1210-8510 Institutional support: RVO:67985971 Keywords : the Augustinian monastery at St Thomas in Prague * monastic libraries * provenance research * early modern period Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  6. Caracterización funcional de la comunidad bacteriana cultivable aislada del suelo de la zona de descarga de la fosa petrolera Bare-9. San Tomé. Edo. Anzoátegui

    OpenAIRE

    Barrios, Arturo

    2011-01-01

    Mediante el presente estudio enmarcado dentro del proyecto Misión Ciencia “Desarrollo y Validación de Nuevas Tecnologías para el Saneamiento Ambiental de Pasivos Generados por la Actividad Petrolera”, dentro del subprefecto “Caracterización del Medio Físico Natural en Áreas Impactadas con Hidrocarburos” se pretende caracterizar funcionalmente la comunidad bacteriana del suelo de la zona de descarga de la fosa petrolera (Bare-9) y así determinar la estructura funcional de la comunidad y grupos...

  7. 5-7 Year Old Children's Conceptions of Behaving Artifacts and the Influence of Constructing Their Behavior on the Development of Theory of Mind (ToM) and Theory of Artificial Mind (ToAM)

    Science.gov (United States)

    Spektor-Precel, Karen; Mioduser, David

    2015-01-01

    Nowadays, we are surrounded by artifacts that are capable of adaptive behavior, such as electric pots, boiler timers, automatic doors, and robots. The literature concerning human beings' conceptions of "traditional" artifacts is vast, however, little is known about our conceptions of behaving artifacts, nor of the influence of the…

  8. La injusticia legal como Juez de la adicción que juzgan: una continuidad en la diferencia paradigmática entre Santo Tomás y Habermas

    Directory of Open Access Journals (Sweden)

    Jose Marcos Miné Vanzella

    2016-06-01

    Full Text Available Questo articolo artigo si propone di identificare una certa filiazione critica del pen- siero di Habermas con la tradizione del pensiero di San Tommaso, attraverso l’aderenza agli elementi fondamentali della persona, della morale e dell’ingiustizia legale come vi- zio del giudice che giudica. Nel primo momento analizza il pensiero  filosofico di San Tommaso sui temi dell’ “Ingiustizia” e dell’ “Ingiustizia del giudice nel giudicare”, a par- tire da una visione generale di quest’opera.  Riguardo alla prima questione, si studiano quattro articoli: se l’ingiustizia è un vizio speciale; se è proprio dell’ingiusto praticare atti ingiusti; se possiamo soffrire l’ingiustizia volontariamente e se l’ingiustizia genericamente è un peccato mortale. Pure la seconda questione studia quattro articoli, cioè: se possiamo giudicare giustamente chi non dipende da noi; se è lecito al giudice, basandosi in quello che gli espongono, giudicare contro la verità che conosce; se il giudice può condannare giustamente chi non è accusato e se può licitamente ridurre la pena. Nel secondo momen- to presenta il pensiero di Habermas riguardo all’ingiustizia del giudice che giudica. Mos- tra il legame di Habermas con la filosofia della persona morale. La persona del giudice partecipa di una realtà mediata simbolicamente e sperimentata in questa mediazione, che è misura dell’imputazione della sua responsablità morale. Questa è ripensata attraverso la sua socializzazione e l’introduzione in un mondo della vita mediato simbolicamente. Si aggiunge il tema dell’ignoranza della legge in San Tommaso alla modalità di ingiustizia legale come vizio del giudice che giudica per ignoranza paradignatica del diritto. Dis- tingue il superamento del solipsismo metodico che esige da parte del giudice decisioni ben fondate: queste si esprimono come argomenti validi davanti alla comunità giuridica. Tale posizione sfocia a comprendere i discorsi di applicazione con perfezionamento della  ponderazione della procedura argomentativa. Si mostra l’aderenza di Habermas ai temi posti da San Tommaso, come pure la sua attualizzazione critica e la sua interpretazione.

  9. Propuesta de ejercicios para el entrenamiento del esfuerzo final en el lanzamiento de jabalina para atletas de São Tomé y Príncipe de la categoría juvenil

    Directory of Open Access Journals (Sweden)

    Ludvik Amaral Vera Cruz

    2009-03-01

    Full Text Available En Sao Tome y Príncipe, como en tanto otros países, ocurre que la preparación de atletas para el lanzamiento de la jabalina, no siempre se realiza con la mayor eficiencia, dada por la ausencia de entrenadores especialistas en esta prueba, por lo que los medios más adecuados no siempre se utilizan y los atletas presentan deficiencias que atentan contra un alto rendimiento. En la técnica de lanzamiento de jabalina, se acostumbra a dividir el movimiento completo en partes que facilitan su enseñanza y aprendizaje, siendo la parte más importante  el esfuerzo final, este llega a constituir del 72 al 75% de rendimiento respecto al movimiento completo y en cuanto al por ciento de volumen anual de los lanzamientos técnicos constituye el 65-75% del volumen total de todas las partes técnica del lanzamiento. En él ocurre una transformación de posturas o gestos muy complejos, lo que hace necesario atender con todas las opciones posibles y es aquí  donde se adolece de recursos o ejercicios que propicien un aprendizaje más adecuado.

  10. Estudio comparativo de la medición del poder corneal central usando el queratómetro manual, el IOLMaster® y el tomógrafo Sirius®

    Directory of Open Access Journals (Sweden)

    Manuel Garza-León

    2016-05-01

    Conclusiones: Para la evaluación de córneas sin enfermedad, la medición del poder queratométrico corneal central con los 3 equipos mostró una alta repetibilidad, sin embargo no hubo una concordancia y la diferencia entre los equipos fue estadísticamente significativa.

  11. Unique Theory of Mind Differentiation in Children with Autism and Asperger Syndrome

    Directory of Open Access Journals (Sweden)

    Michele Tine

    2012-01-01

    Full Text Available This study was designed to determine if ToM abilities of children with autism and Asperger syndrome differentiate into Intrapersonal ToM and Social ToM. A battery of Social and Intrapersonal ToM tasks was administered to 39 children with autism and 34 children with Asperger syndrome. For both groups of children, ToM differentiated and Intrapersonal ToM was stronger than Social ToM. This asymmetry was greater for children with autism, whose Social ToM was especially weak. These results support a differentiated, as opposed to integrated, ToM. Moreover, the findings provide a more thorough understanding of the cognitive abilities associated with autism and Asperger syndrome.

  12. Neural processing associated with cognitive and affective Theory of Mind in adolescents and adults.

    Science.gov (United States)

    Sebastian, Catherine L; Fontaine, Nathalie M G; Bird, Geoffrey; Blakemore, Sarah-Jayne; Brito, Stephane A De; McCrory, Eamon J P; Viding, Essi

    2012-01-01

    Theory of Mind (ToM) is the ability to attribute thoughts, intentions and beliefs to others. This involves component processes, including cognitive perspective taking (cognitive ToM) and understanding emotions (affective ToM). This study assessed the distinction and overlap of neural processes involved in these respective components, and also investigated their development between adolescence and adulthood. While data suggest that ToM develops between adolescence and adulthood, these populations have not been compared on cognitive and affective ToM domains. Using fMRI with 15 adolescent (aged 11-16 years) and 15 adult (aged 24-40 years) males, we assessed neural responses during cartoon vignettes requiring cognitive ToM, affective ToM or physical causality comprehension (control). An additional aim was to explore relationships between fMRI data and self-reported empathy. Both cognitive and affective ToM conditions were associated with neural responses in the classic ToM network across both groups, although only affective ToM recruited medial/ventromedial PFC (mPFC/vmPFC). Adolescents additionally activated vmPFC more than did adults during affective ToM. The specificity of the mPFC/vmPFC response during affective ToM supports evidence from lesion studies suggesting that vmPFC may integrate affective information during ToM. Furthermore, the differential neural response in vmPFC between adult and adolescent groups indicates developmental changes in affective ToM processing.

  13. Combining ability of tomato lines in saladette-type hybrids

    Directory of Open Access Journals (Sweden)

    Marcela Carvalho Andrade

    2014-09-01

    Full Text Available Given the growing importance of the saladette fresh tomato market in Brazil, the objective of this paper was to assess the combining abilities of lines potentially useful as parents of hybridsin this class. The experiment consisted of28 genotypes, 18 hybrids from a partial diallel crossobtained from crossing two groups of tomato lines (Group I, with 9 parents, and Group II, with 2 parents, 8 F1 experimental hybrids, and 2 commercial checks. Traits evaluated were total yield, mean fruit mass, fruit shelf life, shape and percentsoluble solids. Additive genetic effects were generally more important than non-additive effects for all traits evaluated. The TOM-542 and TOM-734 lines, from group I, and the TOM-720 line, from group II, presented high general combining ability (GCA estimates for most of the traits of importance for saladette tomatoes, and were therefore considered suitable parents of hybrids of this class. Higher fruit shelf life of TOM-723 as a parental line compared with TOM-720 (Group II, was mainly attributed to the presence in the former of the norA allele, which controls longer fruit shelf life. F1 hybrids (TOM-542 x TOM-720, (TOM-580 x TOM-720, (TOM-734 x TOM-720, and (TOM-727 x TOM-720 showed good performance and fruit quality and thus constitute possible commercial varieties.

  14. 77 FR 35387 - Granting of Request for Early Termination of the Waiting Period Under The Premerger Notification...

    Science.gov (United States)

    2012-06-13

    ...; Madison Dearborn Capital Partners VI- A, L.P. 05/10/2012 20120774 G Liberty Media Corporation; Live Nation... America; Corvex Master Fund LP. 20120795 G Tom Benson; NBA Development League Holdings. LLC; Tom Benson...

  15. Kuulsaid paare ajaloost : Rosencrantz ja Guildenstern / Ilona Martson

    Index Scriptorium Estoniae

    Martson, Ilona

    1995-01-01

    Tom Stoppardi näidend 'Rosencrantz ja Guildenstern on surnud'. Etendusest Noorsooteatris (esietendus 1989), lavastaja Roman Baskin, peaosades Guido Kangur ja Andrus Vaarik. Filmist, mille autoriks ka Tom Stoppard (USA, Suurbritannia 1990)

  16. Putting theory of mind in its place: psychological explanations of the socio-emotional-communicative impairments in autistic spectrum disorder.

    Science.gov (United States)

    Boucher, Jill

    2012-05-01

    In this review, the history of the theory of mind (ToM) theory of autistic spectrum disorder (ASD) is outlined (in which ToM is indexed by success on false belief tasks), and the explanatory power and psychological causes of impaired ToM in ASD are critically discussed. It is concluded that impaired ToM by itself has only limited explanatory power, but that explorations of the psychological precursors of impaired ToM have been fruitful in increasing understanding of mindreading impairments in ASD (where 'mindreading' refers those abilities that underlie triadic interaction as well as ToM). It is argued that early explanations of impaired mindreading are untenable for various reasons, but that impairments of dyadic interaction in ASD that could lead to impaired ability to represent others' mental states may be the critical psychological cause, or causes, of impaired ToM. The complexity of causal routes to impaired ToM is emphasized.

  17. Putting Theory of Mind in Its Place: Psychological Explanations of the Socio-Emotional-Communicative Impairments in Autistic Spectrum Disorder

    Science.gov (United States)

    Boucher, Jill

    2012-01-01

    In this review, the history of the theory of mind (ToM) theory of autistic spectrum disorder (ASD) is outlined (in which ToM is indexed by success on false belief tasks), and the explanatory power and psychological causes of impaired ToM in ASD are critically discussed. It is concluded that impaired ToM by itself has only limited explanatory…

  18. Unlocking the Mystery of Social Deficits in Autism: Theory of Mind as Key

    Science.gov (United States)

    Blacher, Jan

    2007-01-01

    Theory of mind (ToM) is key to the development of one's social skills. Without ToM, children (or adults) cannot understand or infer the thoughts, feelings, or intentions of others. A lack of ToM skills is considered by some to be a core deficit in autism. ToM affects all interpersonal interactions as well as academics, daily living, following…

  19. Culture and the Sequence of Steps in Theory of Mind Development

    Science.gov (United States)

    Shahaeian, Ameneh; Peterson, Candida C.; Slaughter, Virginia; Wellman, Henry M.

    2011-01-01

    To examine cultural contrasts in the ordered sequence of conceptual developments leading to theory of mind (ToM), we compared 135 3- to 6-year-olds (77 Australians; 58 Iranians) on an established 5-step ToM scale (Wellman & Liu, 2004). There was a cross-cultural difference in the sequencing of ToM steps but not in overall rates of ToM mastery.…

  20. EPA GHG Certification of Medium- and Heavy-Duty Vehicles: Development of Road Grade Profiles Representative of US Controlled Access Highways

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Eric [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Duran, Adam [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Burton, Evan [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gonder, Jeffrey [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kelly, Kenneth [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-05-12

    This report includes a detailed comparison of the TomTom national road grade database relative to a local road grade dataset generated by Southwest Research Institute and a national elevation dataset publically available from the U.S. Geological Survey. This analysis concluded that the TomTom national road grade database was a suitable source of road grade data for purposes of this study.

  1. Intra-Articular Lubricin Gene Therapy for Post-Traumatic Arthritis

    Science.gov (United States)

    2017-09-01

    MaxSi TM Graft Granules in a Rabbit Metaphyseal Defect Model Sponsor Agency: SIRAKOSS Sponsor Contact:: Dr. Tom Buckland, Chief Strategy Officer, +44...Dr. Tom Buckland, Chief Strategy Officer, +44-7545-840504, tom.buckland@sirakoss.com 02/01/2016–09/30/2016, 02/01/2016–09/30/2016, 02/01/2016–06

  2. A Developmental Perspective for Promoting Theory of Mind

    Science.gov (United States)

    Westby, Carol; Robinson, Lee

    2014-01-01

    Social neuroscience research has resulted in changing views of the theory of mind (ToM) construct. Theory of mind is no longer viewed as a unitary construct, but rather as a multidimensional construct comprising cognitive and affective ToM and interpersonal and intrapersonal ToM, each of which has differing neurophysiological/neuroanatomical…

  3. Theory of Mind and Executive Function in Preschoolers with Typical Development versus Intellectually Able Preschoolers with Autism Spectrum Disorder

    Science.gov (United States)

    Kimhi, Yael; Shoam-Kugelmas, Dana; Agam Ben-Artzi, Galit; Ben-Moshe, Inbal; Bauminger-Zviely, Nirit

    2014-01-01

    Children with autism spectrum disorder (ASD) have difficulties in theory of mind (ToM) and executive function (EF), which may be linked because one domain (EF) affects the other (ToM). Group differences (ASD vs. typical development) were examined in both cognitive domains, as well as EF's associations and regressions with ToM. Participants…

  4. Rethinking Theory of Mind in High-Functioning Autism Spectrum Disorder

    Science.gov (United States)

    Scheeren, Anke M.; de Rosnay, Marc; Koot, Hans M.; Begeer, Sander

    2013-01-01

    Background: The sociocommunicative problems in autism spectrum disorder (ASD) are traditionally linked to impairments in Theory of Mind (ToM), the ability to ascribe mental states to others. Although ToM impairments are consistently reported in young children with ASD, findings on more advanced ToM understanding in older individuals with…

  5. Effects and Moderators of a Short Theory of Mind Intervention for Children with Autism Spectrum Disorder: A Randomized Controlled Trial

    NARCIS (Netherlands)

    Begeer, Sander; Howlin, Patricia; Hoddenbach, Elske; Clauser, Cassandra; Lindauer, Ramon; Clifford, Pamela; Gevers, Carolien; Boer, Frits; Koot, Hans M.

    2015-01-01

    Limited perspective taking or "Theory of Mind" (ToM) abilities are a core deficit of autism, and many interventions are aimed to improve ToM abilities. In this study, we investigated the effectiveness of a ToM treatment for children with autism spectrum disorders (ASD) and, for the first time, the

  6. Does Theory of Mind Performance Differ in Children with Early-Onset and Regressive Autism?

    Science.gov (United States)

    Matthews, Nicole L.; Goldberg, Wendy A.; Lukowski, Angela F.; Osann, Kathryn; Abdullah, Maryam M.; Ly, Agnes R.; Thorsen, Kara; Spence, M. Anne

    2012-01-01

    A deficit in theory of mind (ToM), or the ability to infer the mental states of others, has been implicated as one of the major characteristics of Autism Spectrum Disorder (ASD); however, little attention has been devoted to possible differences in ToM ability within ASD. The current study examined ToM performance in children with early-onset…

  7. The Children's Social Understanding Scale: Construction and Validation of a Parent-Report Measure for Assessing Individual Differences in Children's Theories of Mind

    Science.gov (United States)

    Tahiroglu, Deniz; Moses, Louis J.; Carlson, Stephanie M.; Mahy, Caitlin E. V.; Olofson, Eric L.; Sabbagh, Mark A.

    2014-01-01

    Children's theory of mind (ToM) is typically measured with laboratory assessments of performance. Although these measures have generated a wealth of informative data concerning developmental progressions in ToM, they may be less useful as the sole source of information about individual differences in ToM and their relation to other facets of…

  8. Vaid üks on taevas / Kaire Maimets-Volt

    Index Scriptorium Estoniae

    Maimets, Kaire, 1977-

    2006-01-01

    Mängufilmist "Taevas" ("Heaven") : režissöör Tom Tykwer, stsenaristid Krzysztof Piesiewicz ja Krzysztof Kieslowski, peaosas Cate Blanchett : Saksamaa - Itaalia - USA - Prantsusmaa - Suurbritannia 2002. Originaalmuusika Tom Tykwer, valmismuusika Arvo Pärt ("Aliinale", "Peegel peeglis", "Variatsioonid Arinushka tervenemise puhul"). Esilinastus 6. II 2002 Berliini rahvusvahelisel filmifestivalil. Artikli lõpus Tom Tykwerist ja tema filmograafia

  9. Hyper-Theory-of-Mind in Children with Psychotic Experiences

    NARCIS (Netherlands)

    Clemmensen, Lars; van Os, Jim; Skovgaard, Anne Mette; Vaever, Mette; Blijd-Hoogewys, Els M. A.; Bartels-Velthuis, Agna A.; Jeppesen, Pia

    2014-01-01

    Background: Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies in children have documented that alterations in ToM are associated with Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of ToM (HyperToM) and PE in

  10. Theory of mind, insecure attachment and paranoia in adolescents with early psychosis and healthy controls

    NARCIS (Netherlands)

    Korver-Nieberg, Nikie; Fett, Anne-Kathrin J.; Meijer, Carin J.; Koeter, Maarten W. J.; Shergill, Sukhi S.; de Haan, Lieuwe; Krabbendam, Lydia

    2013-01-01

    Impaired Theory of Mind (ToM) is found in adults with schizophrenia and is associated with paranoid symptoms. Insecure attachment is proposed to underlie impaired ToM as well as paranoia. Insight into associations between insecure attachment and impaired ToM skills may help clinicians and patients

  11. Neurobiological correlates of theory of mind in psychosis proneness

    NARCIS (Netherlands)

    Modinos, Gemma; Renken, Remco; Shamay-Tsoory, Simone G.; Ormel, Johan; Aleman, Andre

    2010-01-01

    Theory of mind (TOM) refers to the capacity to infer one's own and other persons' mental states. ToM abilities are compromised in schizophrenia, in association with dysfunctional activity in predominantly prefrontal brain regions. Prior behavioral studies have also suggested ToM deficits in healthy

  12. Materia orgánica en una laguna de la costa de Sinaloa, México: (I : cuantificación total

    Directory of Open Access Journals (Sweden)

    Guadalupe de la Lanza E

    1980-12-01

    Full Text Available The distribution and variation of total organic matter (TOM during the rainy season, was studied in the sediments of the coastal lagoon of Huizache-Caimanero, Sinaloa. Two well defined areas werw detected: one with more than 9% TOM, NE of the lagoon, and other with less than 9% TOM, SW of the lagoon. An almost homogeneous TOM concentration was found from the surface to 15-20 cm depth of the sediment core. This is probably due to the continuous addition of TOM from the terrestrial and submerged vegetation.

  13. Forma da correlação T-S de massas de água das regiões costeira e oceânica entre o Cabo de São Tomé (RJ e a Ilha de São Sebastião (SP, Brasil T-S correlation in water musses of the coastal and oceanic regions between Cabo de São Tomé (RJ and São Sebastião Island (SP, Brazil

    Directory of Open Access Journals (Sweden)

    Luiz Bruner de Miranda

    1985-01-01

    Full Text Available As variações na estrutura e em propriedades de massas de água da plataforma continental e das de água oceânica adjacente são estudadas com base em expressões analíticas das curvas T-S, As medições das variáveis oceanográficas foram feitas por métodos clássicos numa rede de estações hidrografiacas, as quais foram amostradas em cinco intervalos de tempo (5-10 dias cada um, entre os meses de janeiro de 1970 e fevereiro de 1971. A revisão da classificação das massas de água usada sob condições regionais confirma que as Massas de Água Subtropical Profunda (ASTP, Subtropical (AST e Centrando Atlântico Sul (ACAS, são designações diferentes de uma mesma massa de água. A ultima nomenclatura, Água Central do Atlântico Sul (ACAS, é sugerida para indicar a massa de água com índice termohalino (20,0ºC; 36,36 ‰ , a qual e observada sob a Massa de Água Tropical. Esse valor de salinidade e um pouco maior do que o índice termohalino modificado da ACAS (36,20 ‰ e pode ser usado com vantagem nos cálculos volumétricos na área. As expressões polinomiais da curva T-S, cujos coeficientes foram determinados pelo método dos mínimos quadrados, foram usadas em aplicações práticas. Nessas aplicações, foram desenvolvidos métodos alternativos para a determinação da derivada termohalina e da razao de densidade constante (Rρ = αdT/βdS.Characteristics of the structure and sea water properties on the continental shelf and waters adjacent to the continental slope, were studied based on the temperature-salinity (T-S relationships. The water sampling was carried out with standard methods in a network of hydrographie stations worked in five-time intervals (5-10 days, from January 1970 through February 1971. The classification review of the water masses used under regional conditions confirm that the Subtropical-Deep (STDW, Subtropical (STW and South Atlantic Central (SACW Water Masses are different nomenclature for the same water mass; the latter is suggested to indicate a water mass with a thermohaline index given by (20.0 ºC; 36.36 ‰, observed underneath the Tropical Water Mass. This salinity value is slightly higher than the modified thermohaline index of the SACW (36.20 ‰, and can be used with great simplification in volumetric studies in the area. Polynomial expressions of the mean T-S curve, whose coefficients were computed with the least squares method, were given for practical applications. From these applications, alternative methods for the determination of the thermohaline derivative and constant density ratio (Rρ = αdT/βdS were obtained.

  14. The relation between theory of mind and executive functions in children with fetal alcohol spectrum disorders.

    Science.gov (United States)

    Rasmussen, Carmen; Wyper, Katy; Talwar, Victoria

    2009-01-01

    Children with Fetal Alcohol Spectrum Disorders (FASD) are faced with a range of physical, cognitive, behavioral, and/or learning deficits, as well as poor executive functioning and social skills. Theory of mind (ToM) is the ability to understand that one's own perspective may differ from the perspective of another individual. ToM develops around age 4 and is correlated with performance on executive functioning tasks. The goals of this study were to examine ToM performance in young children with FASD, how age was related to ToM performance, and whether ToM abilities were related to underlying executive function difficulties. Fifty-three children (aged 4 to 8 years) participated: 25 children with FASD and 28 control children. All children were tested on measures of ToM, executive functioning, and receptive vocabulary. More children in the FASD group (44%) failed one or both ToM measures than in the control group (25%). Older children with FASD performed worse on ToM than younger children, but this was not the case for the control group. For the FASD group, ToM performance was correlated with a measure of inhibition, but for the control group, ToM was correlated with visual-spatial working memory. Children with FASD have difficulty on ToM tasks, and this difficulty may be related to underlying deficits in inhibition.

  15. The Children's Social Understanding Scale: construction and validation of a parent-report measure for assessing individual differences in children's theories of mind.

    Science.gov (United States)

    Tahiroglu, Deniz; Moses, Louis J; Carlson, Stephanie M; Mahy, Caitlin E V; Olofson, Eric L; Sabbagh, Mark A

    2014-11-01

    Children's theory of mind (ToM) is typically measured with laboratory assessments of performance. Although these measures have generated a wealth of informative data concerning developmental progressions in ToM, they may be less useful as the sole source of information about individual differences in ToM and their relation to other facets of development. In the current research, we aimed to expand the repertoire of methods available for measuring ToM by developing and validating a parent-report ToM measure: the Children's Social Understanding Scale (CSUS). We present 3 studies assessing the psychometric properties of the CSUS. Study 1 describes item analysis, internal consistency, test-retest reliability, and relation of the scale to children's performance on laboratory ToM tasks. Study 2 presents cross-validation data for the scale in a different sample of preschool children with a different set of ToM tasks. Study 3 presents further validation data for the scale with a slightly older age group and a more advanced ToM task, while controlling for several other relevant cognitive abilities. The findings indicate that the CSUS is a reliable and valid measure of individual differences in children's ToM that may be of great value as a complement to standard ToM tasks in many different research contexts. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  16. Theory of mind in middle childhood: Longitudinal associations with executive function and social competence.

    Science.gov (United States)

    Devine, Rory T; White, Naomi; Ensor, Rosie; Hughes, Claire

    2016-05-01

    The vast majority of studies on theory of mind (ToM) have focused on the preschool years. Extending the developmental scope of ToM research presents opportunities to both reassess theoretical accounts of ToM and test its predictive utility. The twin aims of this longitudinal study were to examine developmental relations between ToM, executive function (EF), and teacher-rated social competence in middle childhood. One hundred thirty-seven children (69 males) were followed across a 4-year period spanning middle childhood (M ages at Waves 1 and 2 = 6.05, SD = .35, and 10.81, SD = .35, respectively). Individual differences in ToM were moderately stable across middle childhood. Although there were concurrent associations between ToM and EF at both time points, there were no longitudinal links between these constructs. In contrast, there were concurrent and longitudinal links between ToM and teacher-rated social competence, such that individual differences in ToM predicted later social competence at school. These results are discussed in light of competing theories about the links between ToM and EF and the importance of individual differences in ToM for children's social lives. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  17. Neural responses to affective and cognitive theory of mind in children and adolescents with autism spectrum disorder.

    Science.gov (United States)

    Kim, Eunjoo; Kyeong, Sunghyon; Cheon, Keun-Ah; Park, Bumhee; Oh, Maeng-Keun; Chun, Ji Won; Park, Hae-Jeong; Kim, Jae-Jin; Song, Dong-Ho

    2016-05-16

    Children and adolescents with Autism Spectrum Disorder (ASD) are characterized by an impaired Theory of Mind (ToM). Recent evidence suggested that two aspects of ToM (cognitive ToM versus affective ToM) are differentially impaired in individuals with ASD. In this study, we examined the neural correlates of cognitive and affective ToM in children and adolescents with ASD compared to typically developing children (TDCs). Twelve children and adolescents with ASD and 12 age, IQ matched TDCs participated in this functional MRI study. The ToM task involved the attribution of cognitive and affective mental states to a cartoon character based on verbal and eye-gaze cues. In cognitive ToM tasks, ASD participants recruited the medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), and superior temporal gyrus (STG) to a greater extent than did TDCs. In affective ToM tasks, both ASD and TDC participants showed more activation in the insula and other subcortical regions than in cognitive ToM tasks. Correlational analysis revealed that greater activation of the mPFC/ACC regions was associated with less symptom severity in ASD patients. In sum, our study suggests that the recruitment of additional prefrontal resources can compensate for the successful behavioral performance in the ToM task in ASD participants. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. Theory of mind deficit in bipolar disorder: is it related to a previous history of psychotic symptoms?

    Science.gov (United States)

    Lahera, Guillermo; Montes, José Manuel; Benito, Adolfo; Valdivia, María; Medina, Elena; Mirapeix, Isabel; Sáiz-Ruiz, Jerónimo

    2008-12-15

    It has been hypothesized that a Theory of Mind (ToM) deficit could be a vulnerability marker for psychosis. Recent studies, however, have shown ToM deficits in affective relapses of bipolar disorder as well as in the euthymic phase. This study analyzes the relationship between ToM and a previous history of psychotic symptoms in bipolar disorder. ToM, sustained attention and executive functions were analyzed in 75 bipolar euthymic patients with three or more previous relapses (42 of them had a history of psychotic symptoms and 33 did not) and 48 healthy subjects. ToM was assessed with the Advanced Test by Happé. ToM performance was similar in bipolar patients with or without a history of psychotic symptoms, and in both cases it was significantly reduced as compared with the healthy control group. Similarly, both bipolar groups showed impaired sustained attention and executive functions. This general cognitive deficit partially explains the differences obtained in ToM. The ToM instrument used shows low sensitivity for assessing ToM in bipolar patients and it could partially reflect general cognitive functioning rather than a specific deficit in psychosis. ToM deficit is not a trait marker for psychosis, given that it is present in bipolar disorder regardless of a previous history of psychotic symptoms.

  19. Reading wild minds: A computational assay of Theory of Mind sophistication across seven primate species.

    Directory of Open Access Journals (Sweden)

    Marie Devaine

    2017-11-01

    Full Text Available Theory of Mind (ToM, i.e. the ability to understand others' mental states, endows humans with highly adaptive social skills such as teaching or deceiving. Candidate evolutionary explanations have been proposed for the unique sophistication of human ToM among primates. For example, the Machiavellian intelligence hypothesis states that the increasing complexity of social networks may have induced a demand for sophisticated ToM. This type of scenario ignores neurocognitive constraints that may eventually be crucial limiting factors for ToM evolution. In contradistinction, the cognitive scaffolding hypothesis asserts that a species' opportunity to develop sophisticated ToM is mostly determined by its general cognitive capacity (on which ToM is scaffolded. However, the actual relationships between ToM sophistication and either brain volume (a proxy for general cognitive capacity or social group size (a proxy for social network complexity are unclear. Here, we let 39 individuals sampled from seven non-human primate species (lemurs, macaques, mangabeys, orangutans, gorillas and chimpanzees engage in simple dyadic games against artificial ToM players (via a familiar human caregiver. Using computational analyses of primates' choice sequences, we found that the probability of exhibiting a ToM-compatible learning style is mainly driven by species' brain volume (rather than by social group size. Moreover, primates' social cognitive sophistication culminates in a precursor form of ToM, which still falls short of human fully-developed ToM abilities.

  20. Theory of Mind intervention for outpatients with schizophrenia.

    Science.gov (United States)

    Bechi, Margherita; Spangaro, Marco; Bosia, Marta; Zanoletti, Andrea; Fresi, Francesco; Buonocore, Mariachiara; Cocchi, Federica; Guglielmino, Carmelo; Smeraldi, Enrico; Cavallaro, Roberto

    2013-01-01

    Social disability is one of the critical areas known to be a predictor of daily functioning in schizophrenia. Recent studies showed that impairments in Theory of Mind (ToM) contribute to real-world social functioning and are more strongly associated with community outcomes than other neuropsychological domains of cognition. Several experiments revealed an improving potential of social cognition targeted training, particularly through introduction of verbalisation and explicit manipulation of information about others' mental states. Based on these data, we evaluated longitudinally, with a controlled trial, the feasibility and efficacy of ToM training and the possible influences of daily functioning and IQ on the enhancement of ToM abilities. Thirty outpatients with schizophrenia were recruited and randomly allocated to two groups: ToM Intervention (ToMI), based on verbalisation of selected comic strips representing ToM scenarios, or active control group (ACG). Results showed a significant improvement of ToM abilities among subjects allocated to ToMI compared to ACG, confirming the hypothesis of the enhancing potential of training methods targeting ToM functions. Moreover, we observed no influences of neuropsychological and functional variables on ToM improvement. Development of future studies should take into account possible effects of ToM training on functional outcome, according to the strong associations between ToM abilities and real-world social functioning.

  1. Deficits in theory of mind and social anxiety as independent paths to paranoid features in schizophrenia.

    Science.gov (United States)

    Lysaker, Paul H; Salvatore, Giampaolo; Grant, Megan L A; Procacci, Michele; Olesek, Kyle L; Buck, Kelly D; Nicolò, Giuseppe; Dimaggio, Giancarlo

    2010-12-01

    Research suggests paranoia among persons with schizophrenia may be the result of a number of different psychological processes including deficits in theory of mind (ToM) and social anxiety. To test this hypothesis, this study sought to determine whether a group of highly paranoid persons with and without a ToM deficit could be detected and whether the group with paranoia and better ToM might have high levels of social anxiety. To explore this, a cluster analysis was performed on a group of 102 adults with schizophrenia spectrum disorders in a non-acute phase of illness on the basis of ratings of paranoid features using the Positive and Negative Syndrome Scale and levels of ToM deficit using a factor score which summarized four different ToM assessments. Four groups were produced: High Paranoia/Poor ToM (n = 14); Low Paranoia/Good ToM (n = 22); Low Paranoia/Low Middle ToM (n=29); and High Paranoia/High Middle ToM (n = 23). Groups were then compared on self report of social anxiety. As predicted, the group with levels of high paranoid features and relatively better ToM performance had significantly higher levels of social anxiety than all other groups. Published by Elsevier B.V.

  2. Gene-environment interaction between the oxytocin receptor (OXTR) gene and parenting behaviour on children's theory of mind.

    Science.gov (United States)

    Wade, Mark; Hoffmann, Thomas J; Jenkins, Jennifer M

    2015-12-01

    Theory of mind (ToM) is the ability to interpret and understand human behaviour by representing the mental states of others. Like many human capacities, ToM is thought to develop through both complex biological and socialization mechanisms. However, no study has examined the joint effect of genetic and environmental influences on ToM. This study examined how variability in the oxytocin receptor gene (OXTR) and parenting behavior--two widely studied factors in ToM development-interacted to predict ToM in pre-school-aged children. Participants were 301 children who were part of an ongoing longitudinal birth cohort study. ToM was assessed at age 4.5 using a previously validated scale. Parenting was assessed through observations of mothers' cognitively sensitive behaviours. Using a family-based association design, it was suggestive that a particular variant (rs11131149) interacted with maternal cognitive sensitivity on children's ToM (P = 0.019). More copies of the major allele were associated with higher ToM as a function of increasing cognitive sensitivity. A sizeable 26% of the variability in ToM was accounted for by this interaction. This study provides the first empirical evidence of gene-environment interactions on ToM, supporting the notion that genetic factors may be modulated by potent environmental influences early in development. © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  3. Performances on a cognitive theory of mind task: specific decline or general cognitive deficits? Evidence from normal aging.

    Science.gov (United States)

    Fliss, Rafika; Lemerre, Marion; Mollard, Audrey

    2016-06-01

    Compromised theory of mind (ToM) can be explained either by a failure to implement specific representational capacities (mental state representations) or by more general executive selection demands. In older adult populations, evidence supporting affected executive functioning and cognitive ToM in normal aging are reported. However, links between these two functions remain unclear. In the present paper, we address these shortcomings by using a specific task of ToM and classical executive tasks. We studied, using an original cognitive ToM task, the effect of age on ToM performances, in link with the progressive executive decline. 96 elderly participants were recruited. They were asked to perform a cognitive ToM task, and 5 executive tests (Stroop test and Hayling Sentence Completion Test to appreciate inhibitory process, Trail Making Test and Verbal Fluency for shifting assessment and backward span dedicated to estimate working memory capacity). The results show changes in cognitive ToM performance according to executive demands. Correlational studies indicate a significant relationship between ToM performance and the selected executive measures. Regression analyzes demonstrates that level of vocabulary and age as the best predictors of ToM performance. The results are consistent with the hypothesis that ToM deficits are related to age-related domain-general decline rather than as to a breakdown in specialized representational system. The implications of these findings for the nature of social cognition tests in normal aging are also discussed.

  4. Social neuroscience and theory of mind.

    Science.gov (United States)

    Westby, Carol E

    2014-01-01

    The role of theory of mind (ToM) in autism spectrum disorders and other communication impairments has been an active area of research in the last 30 years. Advances in neuroimaging in the last 10 years have led to the rise of the field of social neuroscience, which has markedly increased the understanding of the neurophysiological/neuroanatomical and neurochemical nature of ToM functioning and deficits in typically developing individuals and in children and adults with a variety of social and communication impairments. The goal of this paper is to (a) describe the current concepts of ToM based on neuroscience research, and (b) present a framework for the dimensions of ToM that have been identified, which can be used to guide assessment and intervention for persons with deficits in ToM that affect social interactions. This article presents neuroscience research that has documented the neurophysiological/neuroanatomical bases for cognitive and affective ToM and interpersonal and intrapersonal ToM as well as neurochemical and epigenetic influences on ToM. This information provides an important framework for assessing ToM deficits in persons with social and communication impairments and developing interventions that target the specific dimensions of ToM deficits. © 2014 S. Karger AG, Basel.

  5. Theory of mind in schizophrenia: error types and associations with symptoms.

    Science.gov (United States)

    Fretland, Ragnhild A; Andersson, Stein; Sundet, Kjetil; Andreassen, Ole A; Melle, Ingrid; Vaskinn, Anja

    2015-03-01

    Social cognition is an important determinant of functioning in schizophrenia. However, how social cognition relates to the clinical symptoms of schizophrenia is still unclear. The aim of this study was to explore the relationship between a social cognition domain, Theory of Mind (ToM), and the clinical symptoms of schizophrenia. Specifically, we investigated the associations between three ToM error types; 1) "overmentalizing" 2) "reduced ToM and 3) "no ToM", and positive, negative and disorganized symptoms. Fifty-two participants with a diagnosis of schizophrenia or schizoaffective disorder were assessed with the Movie for the Assessment of Social Cognition (MASC), a video-based ToM measure. An empirically validated five-factor model of the Positive and Negative Syndrome Scale (PANSS) was used to assess clinical symptoms. There was a significant, small-moderate association between overmentalizing and positive symptoms (rho=.28, p=.04). Disorganized symptoms correlated at a trend level with "reduced ToM" (rho=.27, p=.05). There were no other significant correlations between ToM impairments and symptom levels. Positive/disorganized symptoms did not contribute significantly in explaining total ToM performance, whereas IQ did (B=.37, p=.01). Within the undermentalizing domain, participants performed more "reduced ToM" errors than "no ToM" errors. Overmentalizing was associated with positive symptoms. The undermentalizing error types were unrelated to symptoms, but "reduced ToM" was somewhat associated to disorganization. The higher number of "reduced ToM" responses suggests that schizophrenia is characterized by accuracy problems rather than a fundamental lack of mental state concept. The findings call for the use of more sensitive measures when investigating ToM in schizophrenia to avoid the "right/wrong ToM"-dichotomy. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. „Kdybych o tom mluvila, asi bych to nenazvala sexuálním obtěžováním.“ Sexuální obtěžování ve vysokoškolském prostředí z perspektivy studujících

    Czech Academy of Sciences Publication Activity Database

    Vohlídalová, Marta

    2011-01-01

    Roč. 19, č. 2 (2011), s. 23-35 ISSN 1210-6658 R&D Projects: GA MŠk OK08007 Institutional research plan: CEZ:AV0Z70280505 Keywords : sexual harassment * gender * anti-harassment policy Subject RIV: AO - Sociology, Demography

  7. Cooperação sul-sul como nova tendência da cooperação internacional : o discurso e a prática da cooperação técnica do Brasil com São Tomé e Príncipe para o combate à tuberculose

    OpenAIRE

    Caixeta, Marina Bolfarine

    2014-01-01

    A cooperação internacional atualmente vivencia momento de transição, e uma nova tendência deste tipo de relacionamento emerge com a cooperação Sul-Sul. Essa cooperação entre países em desenvolvimento é parte do fenômeno da ascensão do Sul, no plano da política internacional, que nem tanto se caracteriza pela localização geográfica, mas também pela carga ideológica que traz em si. Vários movimentos e expectativas em prol da descolonização do conhecimento, do respeito às diferentes culturas, da...

  8. „Je nutné, aby lidi měli pocit, že na tom večírku musí být“: Zpráva z konference Strukturální změna na podporu genderové rovnosti ve výzkumných organizacích

    Czech Academy of Sciences Publication Activity Database

    Linková, Marcela

    2014-01-01

    Roč. 15, č. 1 (2014), s. 78-84 ISSN 1213-0028 R&D Projects: GA MŠk(CZ) LE12003 Institutional support: RVO:68378025 Subject RIV: AO - Sociology, Demography http://www.genderonline.cz/cs/issue/36-rocnik-15-cislo-1-2014/406

  9. Nepotřebuju podpatky: s Kateřinou Pioreckou o historických paralelách, o psaní i o tom, jaké to je, stát se literární postavou

    Czech Academy of Sciences Publication Activity Database

    Piorecká, Kateřina; Martínková-Racková, S.

    2017-01-01

    Roč. 28, č. 15 (2017), s. 4-5 ISSN 0862-657X Institutional support: RVO:68378068 Keywords : literary history - historical memory - writing technology * historical memory * writing technology Subject RIV: AJ - Letters, Mass-media, Audiovision

  10. Může sociologie přispět k deficitům veřejných politik? Odpověď na polemické přípěvky Tomáše Katrňáka a Martina Kreidla

    Czech Academy of Sciences Publication Activity Database

    Matějů, Petr; Konečný, Tomáš

    2009-01-01

    Roč. 45, č. 5 (2009), s. 1045-1054 ISSN 0038-0288 R&D Projects: GA ČR GA403/08/0109 Institutional research plan: CEZ:AV0Z70280505 Keywords : higher education * accessibility * inequality Subject RIV: AO - Sociology, Demography Impact factor: 0.562, year: 2009

  11. Augustiniánská knihovna u sv. Tomáše v Praze. I. část: Od založení kláštera do počátku 16. století

    Czech Academy of Sciences Publication Activity Database

    Sladká, Veronika

    2016-01-01

    Roč. 23, 1/2 (2016), s. 127-146 ISSN 1210-8510 Institutional support: RVO:67985971 Keywords : Augustinian convent of Saint Thomas in Prague * monastic libraries * provenance research * library history * librarian practice in the Order of Saint Augustine * Codex Thomaeus Subject RIV: AB - History

  12. Avaliação da habilidade de resolução temporal, com uso do tom puro, em crianças com e sem desvio fonológico Temporal processes ability evaluations with pure tones in children with and with no phonological disorders

    Directory of Open Access Journals (Sweden)

    Lílian Ferreira Muniz

    2007-12-01

    Full Text Available OBJETIVO: verificar o desempenho da resolução temporal em crianças portadoras de desvio fonológico. MÉTODOS: a área de estudo foi uma clínica escola de Fonoaudiologia de uma universidade particular do Recife e teve como participantes 36 crianças, de 6 a 9 anos, subdivididas em um grupo experimental (com desvio fonológico e um grupo controle. Para a coleta de dados foi utilizado o Teste de detecção de intervalos aleatórios proposto por Keith e a análise quantitativa dos dados foi realizada com o SPSS 13 para a aplicação de técnicas de estatística descritiva. RESULTADOS: 94,5% das crianças com desvio fonológico apresentaram resultados alterados para o RGDT, os resultados mostram limiares de detecção de intervalos aleatórios maiores no grupo com desvio fonológico (25,00 a 28,33 ms; tendo sido significativa a diferença entre grupos para cada uma das freqüências testadas; não houve influência das variáveis: freqüência, sexo, idade e série escolar; o tratamento fonoaudiológico não foi um fator determinante; as queixas de aprendizagem mais referidas foram: dificuldade de leitura e dificuldade de compreensão de textos. CONCLUSÃO: crianças com desvio fonológico podem apresentar alteração de processamento temporal e necessitam de mais tempo para detecção de intervalos de tempo entre estímulos auditivos que as crianças sem desvio fonológico. De maneira geral, em ambos os grupos, não houve influência das variáveis: freqüência, sexo, idade, série escolar ou ocorrência de tratamento fonoaudiológico. As queixas de aprendizado podem estar presentes nas crianças com desvio fonológico e alteração de processamento temporal.PURPOSE: to check the performance of temporal processes ability in children with phonological disorders. METHODS: the study took place in a private university of Recife and the participants were 36 volunteers, with ages varying from 6 to 9, of both genders and divided into two groups, with phonological disorders (experimental and a control one. The data was collected using the RGDT (Keith and the analysis made with the SPSS 13 by descriptive statistical techniques. RESULTS: the results show higher levels of Gaps detection on the experimental; the difference between the groups was statistically significant for each frequency tested; there was no influence of the variables: periodicity, gender, age, school level; the speech therapy was not a determinant factor; the main referred learning difficulties were reading and comprehension problems. CONCLUSION: children with phonological disorders can present temporal processes disorders and need more time for intervals detection between auditory stimulations. In a generalized manner, in both groups, there was no difference as for the variable periodicity, gender, age, pertaining to school series or occurrence of speech treatment. The learning complaints can be found in children who have phonological and temporal processes disorders at the same time.

  13. Risky Business : Does recognition reduce uncertainty of the movie industry global box office revenue? * of the movie as a one-liner to reflect the characteristics of the movie industry. notifies that Risky Business (1983) is a comedy-drama movie starring Tom Cruise. The writer intentionally uses the name Master Thesis

    OpenAIRE

    Somburanasin, Monsicha

    2010-01-01

    Introduction Movies are considered entertainment goods. Entertainment is one of the experience industries. Intangibility, perishability and heterogeneity are the most significant characteristics of the movie industry. An emotional reaction of consumers cannot be calculated in the same sense that most other physical goods can. If the movie succeeded in meeting the expectations, ticket price decreases will not necessarily indicate further purchases in the future. There are high risks and uncert...

  14. Comparación de la medición del grosor corneal central medido con el paquímetro incluido en el Wavelight® Ex500 Excimer Laser y el tomógrafo de cámara de Scheimpflug Pentacam® en sujetos sanos

    Directory of Open Access Journals (Sweden)

    Manuel Garza León

    2017-01-01

    Conclusiones: Nuestros resultados demuestran que el paquímetro incluido en el Wavelight® Ex500 Excimer Laser es una buena alternativa para la medición del grosor corneal central al Pentacam® en pacientes sanos.

  15. Using memories to understand others: the role of episodic memory in theory of mind impairment in Alzheimer disease.

    Science.gov (United States)

    Moreau, Noémie; Viallet, François; Champagne-Lavau, Maud

    2013-09-01

    Theory of mind (TOM) refers to the ability to infer one's own and other's mental states. Growing evidence highlighted the presence of impairment on the most complex TOM tasks in Alzheimer disease (AD). However, how TOM deficit is related to other cognitive dysfunctions and more specifically to episodic memory impairment - the prominent feature of this disease - is still under debate. Recent neuroanatomical findings have shown that remembering past events and inferring others' states of mind share the same cerebral network suggesting the two abilities share a common process .This paper proposes to review emergent evidence of TOM impairment in AD patients and to discuss the evidence of a relationship between TOM and episodic memory. We will discuss about AD patients' deficit in TOM being possibly related to their difficulties in recollecting memories of past social interactions. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. The origins of children's metamemory: the role of theory of mind.

    Science.gov (United States)

    Lecce, Serena; Demicheli, Patrizia; Zocchi, Silvia; Palladino, Paola

    2015-03-01

    The relation between preschoolers' theory of mind (ToM) and declarative metamemory (DM) was investigated in two studies. The first study focused on 4-year-old children's (N=106) cognitive and affective ToM and their DM. The data showed a significant association between cognitive (but not affective) ToM and DM, independent of verbal ability, non-verbal ability, and working memory. The second study involved 83 children tested at 4 years 6 months of age (and 6 months later) for cognitive ToM and DM. Here, results showed that early cognitive ToM, in particular false-belief understanding, predicts later DM independent of early verbal ability. These data support a view considering cognitive ToM as a precursor of children's DM. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Comprehension of figurative language in Taiwanese children with autism: The role of theory of mind and receptive vocabulary.

    Science.gov (United States)

    Huang, Su-Fen; Oi, Manabu; Taguchi, Aiko

    2015-01-01

    First-order theory of mind (ToM) is necessary for comprehension of metaphors, and second-order ToM is necessary for comprehension of irony. This study investigated the role of ToM and language ability in comprehending figurative language in 50 Taiwanese children with high-functioning autism spectrum disorders (HFASDs) compared with 50 typically developing children. Results showed that the No-ToM HFASDs group performed worse than the first-order ToM HFASDs group and the second-order ToM HFASDs group in comprehension of metaphors, irony, sarcasm and indirect reproach, but not for indirect request. Receptive vocabulary correlated only with metaphor comprehension. The volatility of results seen among studies in terms of the relationship between ToM and figurative language comprehension is discussed.

  18. Theory of Mind and Executive Functions in Young Bilingual Children.

    Science.gov (United States)

    Dahlgren, SvenOlof; Almén, Helena; Dahlgren Sandberg, Annika

    2017-01-01

    Few studies have explored the relationship between theory of mind (ToM), executive function (EF), and bilingualism at the same time. In this study 14 young bilingual children were compared with monolingual children on a test battery composed of 5 ToM tests, 5 EF tests, and 1 test of general language ability. The result showed that despite significantly lower verbal ability, the bilingual children outperformed the monolingual ones on tests of EF. There were no differences in ToM performance. The authors argue that there is a strong relationship between bilingualism and EF, but, contrary to results from earlier studies, they could not find any relationship between bilingualism and ToM. EF did not predict ToM performance. Lack of a significant relationship could be due to the children's young age and consequently their low scores on the ToM tasks.

  19. The Role of Theory of Mind on Social Information Processing in Children With Autism Spectrum Disorders: A Mediation Analysis.

    Science.gov (United States)

    Mazza, Monica; Mariano, Melania; Peretti, Sara; Masedu, Francesco; Pino, Maria Chiara; Valenti, Marco

    2017-05-01

    Individuals with autism spectrum disorders (ASD) show significant impairments in social skills and theory of mind (ToM). The aim of this study was to evaluate ToM and social information processing abilities in 52 children with ASD compared to 55 typically developing (TD) children. A mediation analysis evaluated whether social information processing abilities can be mediated by ToM competences. In our results, children with autism showed a deficit in social skills and ToM components. The innovative results of our study applying mediation analysis demonstrate that ToM plays a key role in the development of social abilities, and the lack of ToM competences in children with autism impairs their competent social behavior.

  20. On the relation between implicit and explicit Theory of Mind and linguistic competence - An empirical approach

    OpenAIRE

    Herzmann, Charlotte Sonja

    2012-01-01

    Theory of Mind (ToM) research demonstrated 3- to 4-year old children to show false belief (FB) understanding in forced-choice or anticipatory looking behavior. While anticipation is claimed to reflect implicit ToM knowledge which develops early and is not consciously accessible, children s forced choice behavior is believed to represent explicit ToM which allows for conscious access and is seems to be associated with linguistic competence. The present thesis tested the association of children...

  1. Correlative studies of satellite ozone sensor measurements

    International Nuclear Information System (INIS)

    Lovill, J.E.; Ellis, J.S.

    1983-01-01

    Comparisons are made between total ozone measurements made by four satellite ozone sensors (TOMS, SBUV, TOVS and MFR). The comparisons were made during July 1979 when all sensors were operating simultaneously. The TOMS and SBUV sensors were observed to measure less total ozone than the MFR sensor, 10 and 15 Dobson units (DU) respectively. The MFR and TOMS sensors measured less ozone than the TOVS sensor, 19 an 28 DU, respectively. Latitudinal variability of the total ozone comparisons is discussed

  2. Using the Theory of Mind Inventory to Detect a Broad Range of Theory of Mind Challenges in Children with Hearing Loss: A Pilot Study

    Science.gov (United States)

    Hutchins, Tiffany L.; Allen, Lyndsey; Schefer, Maggie

    2017-01-01

    Traditional child-performance measures of theory of mind (ToM) are associated with several limitations. The Theory of Mind Inventory-2 (ToMI-2) is a new broadband caregiver-informant measure designed to tap children's ToM competence. The purposes of this pilot study were to (1) gather preliminary data to explore the scope of the ToM challenges…

  3. Simple Mindreading Abilities Predict Complex Theory of Mind: Developmental Delay in Autism Spectrum Disorders

    Science.gov (United States)

    Pino, Maria Chiara; Mazza, Monica; Mariano, Melania; Peretti, Sara; Dimitriou, Dagmara; Masedu, Francesco; Valenti, Marco; Franco, Fabia

    2017-01-01

    Theory of mind (ToM) is impaired in individuals with autism spectrum disorders (ASD). The aims of this study were to: (i) examine the developmental trajectories of ToM abilities in two different mentalizing tasks in children with ASD compared to TD children; and (ii) to assess if a ToM simple test known as eyes-test could predict performance on…

  4. The relationship between theory of mind and autobiographical memory in high-functioning autism and Asperger syndrome.

    Science.gov (United States)

    Adler, Noga; Nadler, Benny; Eviatar, Zohar; Shamay-Tsoory, Simone G

    2010-06-30

    The relationship between theory of mind (ToM) and autobiographical memory (AM) in high-functioning autism (HFA) and Asperger syndrome (AS) has never been investigated. Here, we show that ToM abilities could be predicted by levels of AM in HFA and AS as compared to controls, suggesting that difficulties in AM are closely related to ToM impairments in HFA and AS.

  5. Evidences of a “protection” of Social-cognition Abilities Against the Effect of Subclinical Psychotic Symptoms in General Population: Thymic Symptoms and Theory of Mind

    OpenAIRE

    Cohen, R.F.; Tubiana-Potiez, A.; Kahn, J.P.

    2015-01-01

    International audience; The relationship between " Theory of Mind " (ToM) or more generally, social cognition and psychotic symptoms is largely supported by the actual literature. What is less known is the relationship between mood symptoms and ToM. Some studies found that bipolar disorder patients as well as depressed remitted patients have worse performances on ToM tasks than healthy subjects. This would explain the poor social abilities of depressive patients and constitute a risk factor o...

  6. Social cognition: empirical contribution. The developmental building blocks of psychopathic traits: revisiting the role of theory of mind.

    Science.gov (United States)

    Sharp, Carla; Vanwoerden, Salome

    2014-02-01

    In the context of personality disorder development, theories of typical and atypical development both emphasize social cognition as an important building block for personality development. Prior claims of intact theory of mind (ToM) abilities in psychopathic individuals have relied upon a narrow conception of ToM as equivalent to "cognitive empathy." In this article, the authors make use of a broader conception of ToM comprising top-down and bottom-up processing, as well as the fractionation of ToM in terms of reduced or excessive ToM function, to examine relationships between ToM and psychopathic traits. A total of 342 adolescents (ages 12-17; Mage 15.39; SD = 1.45; 61.5% females) completed the Movie Assessment for Social Cognition (Dziobek, Fleck, Kalbe, et al., 2006) and the Child Eyes Test (Baron-Cohen, Wheelwright, Hill, Raste, & Plumb, 2001) in addition to three measures of psychopathic traits. Results demonstrated unique relations between the affective components of psychopathy (callous-unemotional traits [CU traits]) and impairment in both top-down and bottom-up ToM. In addition, excessive ToM related to affective components of psychopathy, while reduced or no ToM related to behavioral components of psychopathy. In mediational analyses, bottom-up ToM was shown to be necessary for top-town ToM in its relation with CU traits. Taken together, these results from the study lend support to revisiting the link between ToM and psychopathy.

  7. Using virtual reality to assess theory of mind subprocesses and error types in early and chronic schizophrenia.

    Science.gov (United States)

    Canty, Allana L; Neumann, David L; Shum, David H K

    2017-12-01

    Individuals with schizophrenia often demonstrate theory of mind (ToM) impairment relative to healthy adults. However, the exact nature of this impairment (first- vs. second-order ToM and cognitive vs. affective ToM) and the extent to which ToM abilities deteriorate with illness chronicity is unclear. Furthermore, little is known about the relationships between clinical symptoms and ToM error types (overmentalising, reduced mentalising and no ToM) in early and chronic schizophrenia. This study examined the nature and types of ToM impairment in individuals with early ( n  = 26) and chronic schizophrenia ( n  = 32) using a novel virtual reality task. Clinical participants and demographically-matched controls were administered the Virtual Assessment of Mentalising Ability, which provides indices of first- and second-order cognitive and affective ToM, and quantifies three different types of mentalising errors (viz., overmentalising, reduced mentalising, and no ToM). Individuals with early schizophrenia performed significantly poorer than healthy controls on first-order affective and second-order cognitive and affective ToM, but significantly higher than individuals with chronic schizophrenia on all ToM subscales. Whereas a lack of mental state concept was associated with negative symptoms, overmentalising was associated with positive symptoms. These findings suggest that ToM abilities selectively deteriorate with illness chronicity and error types are related to these individuals' presenting symptomology. An implication of the findings is that social-cognitive interventions for schizophrenia need to consider the nature, time course and symptomatology of the presenting patient.

  8. Hearing Mothers and Oral Deaf Children: An Atypical Relational Context for Theory of Mind

    Science.gov (United States)

    Lecciso, Flavia; Petrocchi, Serena; Marchetti, Antonella

    2013-01-01

    The study assessed Theory of Mind (ToM) abilities in a group of oral deaf children and in their hearing mothers using a battery of ToM tasks. It also investigated the connection between mother and child in ToM performance. Participants were: 17 oral deaf children (aged 5 to 14 years) were paired by gender, age, and mental age with 17 hearing…

  9. Promoting theory of mind in older adults: does age play a role?

    Science.gov (United States)

    Rosi, Alessia; Cavallini, Elena; Bottiroli, Sara; Bianco, Federica; Lecce, Serena

    2016-01-01

    Previous research on age-related changes in Theory of Mind (ToM) showed a decline in older adults, particularly pronounced over 75 years of age. Evidence that ToM may be enhanced in healthy aging people has been demonstrated, but no study has focused on the role of age on the effects of ToM training for elderly people. The present study was designed to examine the efficacy of a ToM training on practiced (ToM Strange Stories) and transfer tasks (ToM Animations) in both young and older adults. The study involved 127 older adults belonging to two age groups: young-old (Mage = 64.41; SD = 2.49; range: 60-69 years) and old-old (Mage = 75.66; SD = 4.38; range: 70-85 years), randomly assigned to either a ToM group or a control group condition. All participants took part in two 2-hour testing sessions and four 2-hour training sessions. Results showed that both young-old and old-old adults in the ToM group condition improved their ability to reason on complex-mental states significantly more than participants in the control group condition. This positive effect of the training was evident on practiced and transfer ToM tasks. Crucially, age did not moderate the effect of the ToM training. These findings demonstrate that young-old and old-old adults equally benefit from the ToM training. Implications for the positive effect of the ToM training in old-old adults are discussed.

  10. The relationship between theory of mind and the executive functions: Evidence from patients with frontal lobe damage.

    Science.gov (United States)

    Yeh, Zai-Ting; Tsai, Ming-Cheng; Tsai, Ming-Dar; Lo, Chiao-Yu; Wang, Kaw-Chen

    2017-01-01

    "Theory of mind" (ToM) refers to the ability to predict others' thoughts, intentions, beliefs, and feelings. Evidence from neuropsychology and functional imaging indicates that ToM is a domain-specific or modular architecture; however, research in development psychology has suggested that ToM is the full development of the executive functions in individuals. Therefore, the relationship between ToM and the executive functions needs to be clarified. Since the frontal lobe plays a critical role in the abilities of ToM and the executive functions, patients with frontal lobe damage were recruited for the present study. Assessments of ToM and the executive functions were performed on 23 patients with frontal lobe damage and 20 healthy controls. When controlling for the executive functions, significant differences between the patient and normal groups were found in the affective component of ToM, but not in the cognitive component. The present study suggests that in various social situations, executing ToM abilities requires logical reasoning processes provided by the executive functions. However, the reasoning processes of affective ToM are independent of executive functions.

  11. Theory of mind and its relationship with executive functions and emotion recognition in borderline personality disorder.

    Science.gov (United States)

    Baez, Sandra; Marengo, Juan; Perez, Ana; Huepe, David; Font, Fernanda Giralt; Rial, Veronica; Gonzalez-Gadea, María Luz; Manes, Facundo; Ibanez, Agustin

    2015-09-01

    Impaired social cognition has been claimed to be a mechanism underlying the development and maintenance of borderline personality disorder (BPD). One important aspect of social cognition is the theory of mind (ToM), a complex skill that seems to be influenced by more basic processes, such as executive functions (EF) and emotion recognition. Previous ToM studies in BPD have yielded inconsistent results. This study assessed the performance of BPD adults on ToM, emotion recognition, and EF tasks. We also examined whether EF and emotion recognition could predict the performance on ToM tasks. We evaluated 15 adults with BPD and 15 matched healthy controls using different tasks of EF, emotion recognition, and ToM. The results showed that BPD adults exhibited deficits in the three domains, which seem to be task-dependent. Furthermore, we found that EF and emotion recognition predicted the performance on ToM. Our results suggest that tasks that involve real-life social scenarios and contextual cues are more sensitive to detect ToM and emotion recognition deficits in BPD individuals. Our findings also indicate that (a) ToM variability in BPD is partially explained by individual differences on EF and emotion recognition; and (b) ToM deficits of BPD patients are partially explained by the capacity to integrate cues from face, prosody, gesture, and social context to identify the emotions and others' beliefs. © 2014 The British Psychological Society.

  12. Integration of technology-based outcome measures in clinical trials of Parkinson and other neurodegenerative diseases.

    Science.gov (United States)

    Artusi, Carlo Alberto; Mishra, Murli; Latimer, Patricia; Vizcarra, Joaquin A; Lopiano, Leonardo; Maetzler, Walter; Merola, Aristide; Espay, Alberto J

    2018-01-01

    We sought to review the landscape of past, present, and future use of technology-based outcome measures (TOMs) in clinical trials of neurodegenerative disorders. We systematically reviewed PubMed and ClinicalTrials.gov for published and ongoing clinical trials in neurodegenerative disorders employing TOMs. In addition, medical directors of selected pharmaceutical companies were surveyed on their companies' ongoing efforts and future plans to integrate TOMs in clinical trials as primary, secondary, or exploratory endpoints. We identified 164 published clinical trials indexed in PubMed that used TOMs as outcome measures in Parkinson disease (n = 132) or other neurodegenerative disorders (n = 32). The ClinicalTrials.gov search yielded 42 clinical trials using TOMs, representing 2.7% of ongoing trials. Sensor-based technology accounted for over 75% of TOMs applied. Gait and physical activity were the most common targeted domains. Within the next 5 years, 83% of surveyed pharmaceutical companies engaged in neurodegenerative disorders plan to deploy TOMs in clinical trials. Although promising, TOMs are underutilized in clinical trials of neurodegenerative disorders. Validating relevant endpoints, standardizing measures and procedures, establishing a single platform for integration of data and algorithms from different devices, and facilitating regulatory approvals should advance TOMs integration into clinical trials. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Ken Jacobs and the Perverted Archival Image

    OpenAIRE

    Gonçalo Pablo

    2016-01-01

    This paper analyses two recent works by American filmmaker Ken Jacobs that deal with aspects of remediation. The first is A Tom Tom Chaser, in which Jacobs records the telecine process that transforms the classic silent film Tom, Tom, the Piper’s Son from chemical into electronic media. The film is riddled with poetic turns inviting the audience to rediscover the medial noise hidden by images. Moreover, Jacobs focuses on the moment of transition from a material medium (the film strip) to the ...

  14. Theory of Mind and social reserve: Alternative hypothesis of progressive Theory of Mind decay during different stages of Alzheimer's disease.

    Science.gov (United States)

    Fliss, Rafika; Le Gall, Didier; Etcharry-Bouyx, Frédérique; Chauviré, Valérie; Desgranges, Béatrice; Allain, Philippe

    2016-01-01

    Although Theory of Mind (ToM) is thought to be impaired in Alzheimer's disease (AD), it remains unclear whether this impairment is linked to the level of task complexity, the heterogeneity of the studied patients, or the implication of executive dysfunctions. To elucidate this point, 42 AD patients, divided into two subgroups [moderate AD (mAD) patients (n = 19) and early AD (eAD) patients (n = 23)], and 23 matched healthy older subjects (HO) were enrolled. All participants were given (1) a false-belief task (cognitive ToM), (2) a revised version of the "Reading the Mind in the Eyes" test (affective ToM), and (3) a composite task designed to assess ToM abilities with minimal cognitive demands. Participants were also given executive tasks assessing inhibition, shifting, and updating processes. We observed a significant impairment of cognitive and composite ToM abilities in eAD patients compared with mAD patients. There was no impairment of affective ToM. Stepwise regression revealed that measures of global efficiency and executive functions (EFs) were the best predictors of progressive decay of ToM scores. These results indicate that cognitive aspects of ToM are more sensitive to AD progression than affective tasks. They also show that ToM abilities are more affected by dementia severity than by task complexity. One explanation of our results is the presence of compensatory mechanisms (social reserve) in AD.

  15. Hyper-Theory-of-Mind in Children with Psychotic Experiences

    OpenAIRE

    Clemmensen, Lars; van Os, Jim; Skovgaard, Anne Mette; Vaever, Mette; Blijd-Hoogewys, Els M. A.; Bartels-Velthuis, Agna A.; Jeppesen, Pia

    2014-01-01

    Background: Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies in children have documented that alterations in ToM are associated with Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of ToM (HyperToM) and PE in children. Children with this type of alteration in ToM infer mental states when none are obviously suggested, and predict behaviour on the basis of these erroneous beliefs. Individuals with HyperT...

  16. Evidence from paranoid schizophrenia for more than one component of theory of mind

    Science.gov (United States)

    Scherzer, Peter; Achim, André; Léveillé, Edith; Boisseau, Emilie; Stip, Emmanuel

    2015-01-01

    We previously reported finding that performance was impaired on four out of five theory of mind (ToM) tests in a group of 21 individuals diagnosed with paranoid schizophrenia (pScz), relative to a non-clinical group of 29 individuals (Scherzer et al., 2012). Only the Reading the Mind in the Eyes Test did not distinguish between groups. A principal components analysis revealed that the results on the ToM battery could be explained by one general ToM factor with the possibility of a latent second factor. As well, the tests were not equally sensitive to the pathology. There was also overmentalization in some ToM tests and under-mentalisation in others. These results led us to postulate that there is more than one component to ToM. We hypothesized that correlations between the different EF measures and ToM tests would differ sufficiently within and between groups to support this hypothesis. We considered the relationship between the performance on eight EF tests and five ToM tests in the same diagnosed and non-clinical individuals as in the first study. The ToM tests shared few EF correlates and each had its own best EF predictor. These findings support the hypothesis of multiple ToM components. PMID:26579026

  17. Põhja-Euroopa vägevaim kokk / Katrin Kurss

    Index Scriptorium Estoniae

    Kurss, Katrin

    2007-01-01

    Rahvusvahelisest kokkade võistlusest "Global Chef Challenge" ning seal osalenud kokkadest: Tom Victor Gausdal Norrast ; Carina Brydling Rootsist ; Thorsten Schmidt Taanist ; Simon Hulstone Suurbritanniast

  18. Evidence from paranoid schizophrania for more than one component of theory of mind

    Directory of Open Access Journals (Sweden)

    Peter eScherzer

    2015-10-01

    Full Text Available We previously reported finding that performance was impaired on four out of five theory of mind (ToM tests in a group of 21 individuals diagnosed with paranoid schizophrenia (pScz, relative to a non-clinical group of 29 individuals (Scherzer, Léveillé, Achim, Scherzer, Boisseau, & Stip, 2012. Only the Reading the Mind in the Eyes Test (RMET did not distinguish between groups. A principal components analysis revealed that the results on the ToM battery could be explained by one general ToM factor with the possibility of a latent second factor. As well, the tests were not equally sensitive to the pathology. There was also overmentalization in some ToM tests and under-mentalisation in others. These results led us to postulate that there is more than one component to ToM. We hypothesized that correlations between the different EF measures and ToM tests would differ sufficiently within and between groups to support this hypothesis. We considered the relationship between the performance on eight EF tests and five ToM tests in the same diagnosed and non-clinical individuals as in the first study. The ToM test shared few EF correlates and each had its own best EF predictor.. These findings support the hypothesis of multiple ToM components

  19. Theory of mind correlates with clinical insight but not cognitive insight in patients with schizophrenia.

    Science.gov (United States)

    Zhang, Qi; Li, Xu; Parker, Giverny J; Hong, Xiao-Hong; Wang, Yi; Lui, Simon S Y; Neumann, David L; Cheung, Eric F C; Shum, David H K; Chan, Raymond C K

    2016-03-30

    Research on the relationship between insight and social cognition, in particular Theory of Mind (ToM), in schizophrenia has yielded mixed findings to date. Very few studies, however, have assessed both clinical insight and cognitive insight when examining their relationships with ToM in schizophrenia. The current study thus investigated the relationship between clinical insight, cognitive insight, and ToM in a sample of 56 patients with schizophrenia and 30 healthy controls. Twenty-seven patients were classified as low in clinical insight according to their scores on the 'insight' item (G12) of the Positive and Negative Syndrome Scale (PANSS). Moreover, cognitive insight and ToM were assessed with the Beck Cognitive Insight Scale (BCIS) and the Yoni task, respectively. The results indicated that patients with poor clinical insight performed worse on tasks of second-order cognitive and affective ToM, while the ToM performance of patients with high clinical insight was equivalent to that of healthy controls. Furthermore, while clinical insight was correlated with ToM and clinical symptoms, cognitive insight did not correlate with clinical insight, ToM, or clinical symptoms. Clinical insight thus appears to be an important factor related to ToM in schizophrenia. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  20. Kuressaare rannahoone = Kuressaare public beachfront building / Hannes Koppel

    Index Scriptorium Estoniae

    Koppel, Hannes

    2011-01-01

    2010. aastal valminud arhitekt Hannes Koppeli (Asum Arhitektid OÜ) projekteeritud Kuressaare rannahoonest. Insenerid Tom Arula ja Tõnu Peipman (Printsiip OÜ). Projekt: 2008. Praegusest Kuressaarest