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Sample records for anestesia local intraarticular

  1. Estudo comparativo entre anestesia espinhal e anestesia local com infusão de propofol para artroscopia do joelho

    OpenAIRE

    Silva,Robson Rocha da; Matos,Marcos Almeida; Madureira,Gleise; Santos,Indiara Gouveia dos

    2012-01-01

    OBJETIVO: Anestesia espinhal é um procedimento seguro e bem documentado para artroscopia do joelho; entretanto, custo maior e algumas complicações têm sido relatados. Por outro lado muitos ortopedistas são relutantes ao uso de anestesia local pelo receio de conversão para anestesia geral ou controle inadequado da dor. O propósito deste trabalho é comparar a anestesia local com anestesia espinhal em dois grupos de pacientes submetidos à artroscopia do joelho. MÉTODOS: Sessenta e cinco paciente...

  2. Anestesia raquídea versus anestesia intrarticular en cirugía artroscópica de rodilla. [Spinal anesthesia versus intra-articular anesthesia in arthroscopic surgery of the knee.

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    Lucas Daniel Marangoni

    2016-11-01

      Discusión Conclusión: Las  ventajas encontradas a favor de la anestesia intraarticular fueron: Estadías hospitalarias acortadas, se evitaron efectos indeseables de la anestesia raquídea: bloqueo motor, nauseas, vómitos, hipotensión, pérdida transitoria de esfínter urinario y retención urinaria (globo vesical. Disminución de los costos y mayor aceptación de los pacientes.

  3. Eventraciones, cirugía ambulatoria con anestesia local

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    ACEVEDO F,ALBERTO; VITERBO S,AQUILES; BRAVO L,JORGE; DELLEPIANE L,VERÓNICA

    2006-01-01

    Las eventraciones constituyen la tercera causa de consulta en el Centro de Cirugía ambulatoria del CRS Cordillera, con un 11,7% y constituyen un frecuente motivo de consulta en los servicios de cirugía del país. En esta presentación damos cuenta de la cirugía ambulatoria con anestesia local de las eventraciones de tamaño pequeño y mediano. Se midieron el dolor operatorio y la satisfacción de los pacientes mediante escala visual analógica (EVA), y las complicaciones con controles efectuados a ...

  4. Efeitos do uso da adrenalina na anestesia local odontológica em portador de coronariopatia

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    Neves,Ricardo Simões; Neves,Itamara Lucia Itagiba; Giorgi,Dante Marcelo Artigas; Grupi,Cesar José; César,Luís Antonio Machado; Hueb,Whady; Grinberg,Max

    2007-01-01

    FUNDAMENTO: A literatura é controversa no que se refere ao uso de vasoconstritores para anestesia local em cardiopatas, havendo preocupação com a indução de descompensação cardíaca. OBJETIVO: Avaliar parâmetros eletrocardiográficos e de pressão arterial durante procedimento odontológico restaurador sob anestesia local com e sem vasoconstritor em portadores de doença arterial coronária. MÉTODOS: Neste estudo foram avaliados 62 pacientes. As idades variaram de 39 a 80 anos (média de 58,7 + 8,8)...

  5. Efeitos cardiovasculares da anestesia local com vasoconstritor durante exodontia em coronariopatas

    OpenAIRE

    Conrado,Valeria C. L. S.; Andrade,Januário de; Angelis,Gabriella A. M. C. de; Andrade,Ana Carolina P. de; Timerman,Lilia; Andrade,Mercedes M.; Moreira,Dalmo R.; Sousa,Amanda G. M. R.; Sousa,J. Eduardo M. R.; Piegas,Leopoldo S.

    2007-01-01

    OBJETIVO: Avaliar a ocorrência de variáveis detectoras de isquemia miocárdica, durante ou após o tratamento odontológico, sob anestesia com vasoconstritor (adrenalina). MÉTODOS: Foram incluídos 54 pacientes coronariopatas submetidos a exodontia sob anestesia local com ou sem vasoconstritor, divididos em dois grupos (sorteio por envelope): grupo I, composto por 27 que receberam anestésico com vasoconstritor; e grupo II, composto por 27 que receberam anestésico sem vasoconstritor. Todos os paci...

  6. [Intravesical botulinum toxin under local anestesia as ambulatory procedure.

    Science.gov (United States)

    Fabuel Alcañiz, José Javier; Martínez Arcos, Laura; Jimenez Cidre, Miguel; Burgos Revilla, Francisco Javier

    2017-09-01

    Bladder hyperactivity is described as the presence of "voiding urgency, generally associated with increased daytime frequency and nocturia, with or without urinary incontinence, in the absence of urinary tract infection or other obvious pathology". Onabotulinum toxin A (BTA) is a recommendable therapeutic option in case of failure, contraindication or refusal of the conservative therapy or other non-pharmacological therapies. The injection of BTA in the detrusor has been performed under local, regional or general anesthesia either in the conventional or major ambulatory surgery operative room or in the cystoscopy room. The objective of this paper is to describe the procedure to perform BTA therapy as an ambulatory operation under intravesical local anesthesia in the cystoscopy room, describing its advantages and limitations.

  7. Toracoscopia diagnóstica com anestesia local: metodologia e aplicações

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    Luís Rocha

    1998-01-01

    Full Text Available RESUMO: A toracoscopia assume cada vez mais um papel importante no diagnóstico e terapêutica de muitos doentes com derrames pleurais recidivantes. É um método simples e bern tolerado, com elevado valor diagnóstico, permitindo uma intervenção mais precoce. Além do diagnóstico permite controlar derrames pleurais recidivantes e malignos, o que poderá complementarmente ter importância de ordem clínica no tratamento e melboria da qualidade de vida do doente. Apesar do número de complicações reduzido e da sua pequena importância, pensamos que se trata de uma técnica a indicar em base individual, tendo em conta o risco/beneficio. Os autores abordam a técnica e metodologia utilizada na toracoscopia, suas contra-indicações, complicações e indicações, fazendo uma revisão teórica dos resultados descritos na literatura e realçando a modalidade anestésica que utilizam: a anestesia local com ajuda de pré-medicação. SUMMARY: Diagnostic thoracoscopy and sometimes therapeutic, assumes an important role in the etiology and symptoms relief of many patients with recurrent pleural effusions. It's a simple and well tolerable method, with high diagnostic yield, that contributes to an earlier intervention. It can control malignant and recurrent pleural effusions, which will have an important role in the treatment and quality of the patient's life. In spite of the number of complications being small and of lack of importance, we think that the use of thoracoscopy is to be decided in an Individual basis, weighting risks and benefits. The authors summarise the technique and methodology, their contraindications, complications and indications, reviewing some published results, emphasising the anaesthesia method and some information supporting local anaesthesia with pré-medication. Key-Words: Thoracoscopy, Local anaesthesia, Pleural effusion, Pleurodesis, Talc poudrage, Palavras-chave: Toracoscopia, Anestesia local, Derrame pleural, Pleurodese

  8. Intra-Articular Synovial Sarcomas: Incidence and Differentiating Features from Localized Pigmented Villonodular Synovitis

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    D. Nordemar

    2015-01-01

    Full Text Available Purpose. To determine the incidence of intra-articular synovial sarcomas and investigate if any radiological variables can differentiate them from localized (unifocal pigmented villonodular synovitis (PVNS and if multivariate data analysis could be used as a complementary clinical tool. Methods. Magnetic resonance images and radiographs of 7 cases of intra-articular synovial sarcomas and 14 cases of localized PVNS were blindedly reviewed. Variables analyzed were size, extra-articular growth, tumor border, blooming, calcification, contrast media enhancement, effusion, bowl of grapes sign, triple signal intensity sign, synovial low signal intensity, synovitis, age, and gender. Univariate and multivariate data analysis, the method of partial least squares-discriminant analysis (PLS-DA, were used. Register data on all synovial sarcomas were extracted for comparison. Results. The incidence of intra-articular synovial sarcomas was 3%. PLS-DA showed that age, effusion, size, and gender were the most important factors for discrimination between sarcomas and localized PVNS. No sarcomas were misclassified as PVNS with PLS-DA, while some PVNS were misclassified as sarcomas. Conclusions. The most important variables in differentiating intra-articular sarcomas from localized PVNS were age, effusion, size, and gender. Multivariate data analysis can be helpful as additive information to avoid a biopsy, if the tumor is classified as most likely being PVNS.

  9. Anestesia local em reconstruções amplas na face - série de casos

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    Hamilton Aleardo Gonella

    2015-10-01

    Full Text Available Introdução: A anestesia local e os bloqueios anestésicos loco-regionais sãode ampla aplicação na medicina e em especial na cirurgia plástica,abrangendo praticamente toda a especialidade, seja nas cirurgiasreparadoras ou nas estéticas. Objetivo: A presente série de casos tem comoobjetivo mostrar possibilidades em terapêuticas cirúrgicas, na cirurgia plástica,exclusivamente em procedimentos reparadores, em nível ambulatorial ehospital-dia. Materiais e métodos: Os pacientes são selecionados de acordocom idade, condições clínicas, comorbidades e tipo de cirurgia, na PoliclínicaMunicipal. Um protocolo para casos selecionados, com pacientes bemesclarecidos e cooperativos, preferencialmente com idade acima de 50 anos,sem comorbidades ou com doenças sistêmicas leves. É preconizada aexérese com margens oncológicas amplas e reconstrução primária comenxertos e retalhos baseados em tecidos locais. Caso 1: PAG, 75 anos, sexo feminino, lesão cutânea em pálpebra inferior direita com 14 meses de evolução. Exérese ampla e retalho de Mustardè. Caso 2: FAF, 80 anos, sexo feminino, pele extremamente doente, com lesãoem asa nasal direita há 11 meses. Exérese ampla e reconstrução com retalhofrontal e nasolabial. Caso 3: GT, 76 anos, sexo feminino, com lesão extensa em regiãoperiorbitária inferior direita. Exérese ampla e retalho de Mustardè.caso 4: FAL, 62 anos, sexo masculino, CBC biopsiado em asa nasal direita há13 meses. Exérese ampla e reconstrução com retalho frontal. Discussão: Os bloqueios anestésicos em geral demandam bomconhecimento anatômico, porte cirúrgico adequado, rapidez e habilidade naexecução, devido a menor duração da anestesia e pelo desconfortocomumente referido pelos pacientes que permanecem no mesmo decúbitopor tempo prolongado. É primordial o cálculo do volume de anestésico a serutilizado para cada pessoa, de modo a não exceder as doses tóxicas e causarcomplicações no ato.

  10. Tratamento cirúrgico das hérnias inguinais sob anestesia local em ambulatório

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    Rafael Melillo Laurino Neto

    Full Text Available OBJETIVOS: Apresentar o programa e avaliar a tolerância dos pacientes à correção das hérnias inguinais em ambulatório sob anestesia local. MÉTODO: Foram analisados 61 pacientes submetidos a tratamento cirúrgico de hérnia inguinal unilateral não complicada, sob anestesia local em ambulatório no Serviço de Cirurgia Geral do Conjunto Hospitalar do Mandaqui, entre fevereiro de 2000 e agosto de 2002. Respeitandose rígidos critérios na seleção dos pacientes, e com os mesmos sob sedação e monitorização contínua, realizou-se bloqueio de campo conforme padronização do serviço. A técnica de reforço da parede abdominal foi definida levando-se em consideração o tipo de hérnia, idade do paciente e sua atividade profissional. Todos os pacientes receberam alta hospitalar em até quatro horas após a cirurgia respeitando-se as condições estabelecidas pela resolução CFM nº 1.409/94, com orientações precisas quanto a possíveis complicações imediatas e retorno para atendimento em Pronto-Socorro caso necessário. RESULTADOS: O tempo cirúrgico médio foi de 1h30min. Quanto ao tipo de hérnia, segundo a classificação de Nyhus, prevaleceu o tipo III B (36%, seguido dos tipos III A (34,5% e II (26,2%. A técnica de reforço mais utilizada foi a de Lichtenstein (80,3%. Quanto à avaliação da dor intra-operatória, 73,8% dos pacientes deram notas igual ou inferior a 3 numa escala de 0 a 10 e 95% afirmaram que se submeteriam novamente a tal procedimento sob anestesia local. CONCLUSÕES: O tratamento cirúrgico das hérnias inguinais sob anestesia local em ambulatório, é procedimento seguro e bem aceito pela maioria dos pacientes quando realizado de forma padronizada.

  11. Colecistectomía con anestesia local como recurso en el paciente anciano Cholecystectomy with local anesthesia as a resource in the elderly

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    Roberto Del Campo Abad

    2011-03-01

    Full Text Available Ante un paciente con colecistitis aguda lo ideal es extirpar la vesícula biliar. A veces se presentan situaciones especiales en ancianos desnutridos, con deterioro de su estado general, en los que una intervención con anestesia prolongada, incluso con medios pocos invasivos como la videocirugía, pone en peligro la vida del enfermo. En tales casos la colecistectomía con anestesia local es una alternativa que se puede considerar.In the case of a patient presenting with acute cholescystectomy ideally is to remove the gallbladder. Sometimes there are special situations in malnourished elderlies with deterioration of its general status in whom a lengthy anesthesia intervention, even using not much invasive means as the videosurgery, put at risk the life of patient. In such cases the cholescystectomy with local anesthesia is an alternative that must to be taken into account.

  12. Local anesthetics after total knee arthroplasty: intraarticular or extraarticular administration? A randomized, double-blind, placebo-controlled study

    DEFF Research Database (Denmark)

    Andersen, L.O.; Kristensen, B.B.; Husted, H.

    2008-01-01

    BACKGROUND: High-volume local infiltration analgesia with additional intraarticular and wound administration of local anesthetic has been shown to be effective after knee replacement, but the optimum site of administration of the local anesthetic (i.e. intraarticular or extraarticular) has not been......-volume infiltration analgesia technique. Further studies are required to define the optimal site of administration of local anesthetic following knee replacement surgery Udgivelsesdato: 2008/12...... or to receive 20 mL ropivacaine (0.2%) intraarticularly plus 30 mL ropivacaine (0.2%) in the extraarticular wound space 24 hours postoperatively. Pain intensity at rest and with mobilization was recorded for 4 hours after administration of additional local anesthetics. RESULTS: Intensity of pain at rest, during...

  13. Anestesia local por tumescência com lidocaína em cadelas submetidas a mastectomia

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    C.J.X. Abimussi

    2013-10-01

    Full Text Available O presente estudo investigou os benefícios da anestesia por tumescência com lidocaína em cadelas submetidas à mastectomia, visando ao conforto do paciente e à sua recuperação pós-operatória. Foram utilizados sete animais, de peso e raças variadas, que apresentavam neoplasia em região de cadeia mamária e que foram submetidos à cirurgia de mastectomia. Todos os animais receberam o mesmo protocolo anestésico, sendo utilizado como MPA a associação entre acepromazina e morfina, nas doses de 0,04mg/kg e 0,4mg/kg (IM, respectivamente. Após 15 minutos, foi alocado um cateter em veia cefálica e realizou-se a indução com propofol 4mg/kg e midazolam 0,2mg/kg, seguida de manutenção anestésica com isofluorano. Posteriormente à instrumentação, procedeu-se à técnica de anestesia por tumescência com solução gelada composta por ringer lactato, lidocaína 2% sem vasoconstritor e adrenalina, em um volume total de 15mL/kg. Em média, o tempo de duração do procedimento foi de 74±18 minutos. O pico plasmático de lidocaína deu-se entre 30 e 60 minutos após a infiltração da solução. O resgate analgésico foi realizado após sete horas, aproximadamente, da infiltração. Pode-se concluir que a anestesia por tumescência com lidocaína deve ser considerada como constituinte do protocolo anestésico e analgésico de cadelas a serem submetidas à cirurgia de mastectomia, proporcionando estabilidade de parâmetros, segurança e recuperação pós-operatória de boa qualidade.

  14. Procedimentos cirúrgicos em pacientes proctológicos selecionados, sob anestesia local: estudo de 150 casos

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    HENRIQUES Alexandre Cruz

    2000-01-01

    Full Text Available Experiência no tratamento de 150 pacientes portadores de afecções anorretais e da região sacrococcígea operados sob anestesia local no Hospital de Ensino da Faculdade de Medicina do ABC, São Bernardo do Campo, SP, no período de março de 1995 a março de 1998. Descrevem a técnica anestésica empregada, operações realizadas e a tolerância ao procedimento. A morbidade intra-operatória foi de 10,6% (16 pacientes e a pós-operatória de 6% (9 pacientes. A idade dos pacientes variou entre 15 e 92 anos de idade, com média de 42 anos; 58% eram do sexo masculino e 42% feminino. O tempo médio de cirurgia foi de 45 minutos e o de permanência hospitalar foi de 8 horas. Todos os pacientes foram orientados sobre a técnica anestésica, suas vantagens e desvantagens, e somente após sua aprovação, a cirurgia era programada. Internação hospitalar foi necessária em cinco pacientes (3,3%. Em nenhum caso foi necessário modificar a técnica anestésica. Interrogados, 96,7% dos pacientes afirmaram não sentir dor durante a operação e que repetiriam o procedimento. Conclui-se que o tratamento cirúrgico das afecções orificiais e da região sacrococcígea com anestesia local além de viável e seguro, é bem aceito pelos pacientes.

  15. Herniorrafia inguinal em crianças: valor da anestesia local associada Inguinal hernia repair in children: importance of local anesthesia association

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    José Guilherme Minossi

    2002-07-01

    Full Text Available OBJETIVO: Descrever uma técnica de anestesia local no tratamento de hérnias inguinais em crianças. MÉTODO: Foram operadas 48 crianças com hérnias inguinais sob anestesia local na Santa Casa de Misericórdia de Cerqueira César, SP, sendo 34 do sexo masculino e 14 do sexo feminino, com idades entre 3 meses e 12 anos. Apenas quatro crianças tinham hérnia bilateral. A anestesia local foi realizada com lidocaína a 1% na dose de 5 mg/kg de peso através do bloqueio dos nervos abdominogenitais próximos à espinha ilíaca ântero-superior, à altura do anel inguinal externo e na pele ao redor da incisão. A sedação foi feita com cetamina na dose de 1 a 2 mg/kg e diazepam 0,2 a 0,4 mg/kg de peso. RESULTADOS: Todas as cirurgias puderam ser realizadas com tranqüilidade com este método, com exceção de uma criança em que o bloqueio não foi efetivo e a anestesia complementada com inalação de halogenado, sob máscara. Como complicações pós-operatórias, ocorreram três hematomas, sendo um de parede e dois em bolsa escrotal, todos com boa evolução. CONCLUSÕES: O uso da anestesia local associada à sedação é procedimento simples e seguro para realizar herniorrafias inguinais em crianças.AIM: To describe an anesthetic technique, as well as the results of surgical treatment of the inguinal hernia in children. PATIENTS/METHODS: Forty-eight patients were submitted to inguinal hernia repair under local anesthesia at "Santa Casa de Misericórdia de Cerqueira César", State of São Paulo, Brazil. There were 34 male and 14 female patients, range from 3 months to 12 years old. Local anesthesia was performed with a dose of 5 mg/kg body weight of 1% lidocaine through iliohypogastric and ilioinguinal nerve blocks, medially to the anterior superior iliac spine, and at level of the pubic tubercle. Sedation was done with an association of ketamine (1 to 2 mg/kg and diazepam (0,2 to 0,4 mg/kg. RESULTS: In all patients except one the procedure was

  16. Efeitos cardiovasculares da anestesia local com vasoconstritor durante exodontia em coronariopatas Cardiovascular effects of local anesthesia with vasoconstrictor during dental extraction in coronary patients

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    Valeria C. L. S. Conrado

    2007-05-01

    Full Text Available OBJETIVO: Avaliar a ocorrência de variáveis detectoras de isquemia miocárdica, durante ou após o tratamento odontológico, sob anestesia com vasoconstritor (adrenalina. MÉTODOS: Foram incluídos 54 pacientes coronariopatas submetidos a exodontia sob anestesia local com ou sem vasoconstritor, divididos em dois grupos (sorteio por envelope: grupo I, composto por 27 que receberam anestésico com vasoconstritor; e grupo II, composto por 27 que receberam anestésico sem vasoconstritor. Todos os pacientes foram submetidos a monitoração eletrocardiográfica com Holter por 24 horas, a Doppler-ecocardiografia realizada antes e após intervenção odontológica, e a dosagem dos marcadores bioquímicos antes e 24 horas após a exodontia (creatina cinase fração MB [CK-MB] massa, CK-MB atividade e troponina T. A freqüência cardíaca e a pressão arterial nas fases pré-anestesia, pós-anestesia e pós-exodontia também foram aferidas. A Doppler-ecocardiografia teve como objetivo avaliar a contratilidade segmentar do ventrículo esquerdo e a eventual ocorrência de insuficiência mitral. Em todos os casos foi mantido o protocolo farmacológico habitual prescrito pelo cardiologista. RESULTADOS: Três pacientes do grupo I apresentaram depressão do segmento ST (1,0 mm durante a aplicação da anestesia, dois outros pacientes do mesmo grupo tiveram elevação da CK-MB massa, e em nenhum caso foi verificada presença de isquemia avaliada pelos demais métodos. Não houve registro, neste estudo, de precordialgia, arritmias e ocorrência ou agravamento de hipocontratilidade segmentar do ventrículo esquerdo ou insuficiência mitral. CONCLUSÃO: A exodontia praticada sob uso de anestesia com adrenalina 1:100.000 não implica riscos isquêmicos adicionais quando realizada com boa técnica anestésica e manutenção do tratamento farmacológico prescrito pelo cardiologista.OBJECTIVE: To evaluate the occurrence of variables detecting myocardial ischemia

  17. Anestesia local para tratamento cirúrgico de hérnia inguinal unilateral pela técnica de Lichtenstein

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    Roberta Costa Vargas

    2015-10-01

    Full Text Available A hérnia inguinal é afecção muito prevalente com impacto sócio-econônimo relevante no mundo e também no nosso meio, acometendo aproximadamente 1,5% da população geral e 5% da população do sexo masculino. O tratamento recomendado é o cirúrgico o qual tem passado por importantes avanços nas últimas duas décadas. Diferentes técnicas anestésicas têm sido propostas para a realização desses procedimentos, incluindo a anestesia local, regional e a geral. O objetivo deste relato é apresentar o caso de paciente com hérnia inguinal unilateral, submetido à hernioplastia inguinal sob anestesia local. O paciente é homem, cinquenta e quatro anos, diabético e portador de glaucoma, sem antecedentes anestésico cirúrgicos, o queal foi submetido à correção de hérnia inguinal direita por uma hora sob anestesia local acompanhada de sedação, sem qualquer complicação intra ou pós-operatória pela técnica de Lichtenstein. A anestesia local com sedação mostra-se um método seguro, eficaz, com baixos índices de complicações imediatas e alto índice de satisfação para pacientes selecionados, portadores de hérnia inguinal.

  18. Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection

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    Kim SR

    2016-11-01

    , polymeric nanoparticles, electrostatic interaction, intra-articular injection, local delivery, hyaluronic acid

  19. Prostate innervation and local anesthesia in prostate procedures Inervação prostática e anestesia local em procedimentos prostáticos

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    Alexandre Oliveira Rodrigues

    2002-01-01

    Full Text Available The nerve supply of the human prostate is very abundant, and knowledge of the anatomy contributes to successful administration of local anesthesia. However, the exact anatomy of extrinsic neuronal cell bodies of the autonomic and sensory innervation of the prostate is not clear, except in other animals. Branches of pelvic ganglia composed of pelvic (parasympathetic and hypogastric (sympathetic nerves innervate the prostate. The autonomic nervous system plays an important role in the growth, maturation, and secretory function of this gland. Prostate procedures under local anesthesia, such as transurethral prostatic resections or transrectal ultrasound-guided prostatic biopsy, are safe, simple, and effective. Local anesthesia can be feasible for many special conditions including uncomplicated prostate surgery and may be particularly useful for the high-risk group of patients for whom inhalation or spinal anesthesia is inadvisable.A prostáta, uma das glândulas sexuais acessórias masculinas, possui inervação muito rica. A anatomia detalhada dos corpos neuronais extrínsecos responsáveis pela inervação autonômica e sensorial da próstata não está totalmente esclarecida, exceto em animais. A próstata é inervada pelos nervos pélvico (parassimpático e hipogástrico (simpático, ramos dos gânglios nervosos pélvicos. O sistema nervoso autonômico possui importante papel no crescimento, maturação e na função secretora desta glândula. Alguns procedimentos prostáticos, como resecção transuretral ou biópsia transretal guiada por ultra-sonografia, são simples, eficazes e seguros com o uso de anestesia local. Esta opção pode ser factível frente à várias condições especiais, como cirurgias prostáticas simples, sendo particularmente útil no grupo de pacientes de alto risco cirúrgico, onde a anestesia inalatória ou espinhal não é aconselhável.

  20. "AvaliaÃÃo da dor de crianÃas submetidas a anestesia local odontolÃgica com seringa convencional e com seringa controlada por computador"

    OpenAIRE

    Mirella de Sousa Pereira

    2014-01-01

    A dor constitui fenÃmeno multifatorial, podendo ter carÃter psicolÃgico e cultural. Estudos apontam que a anestesia local odontolÃgica à a maior causadora de dor e ansiedade em pacientes no consultÃrio odontolÃgico. Desta forma, o objetivo deste estudo foi avaliar as reaÃÃes em relaÃÃo a dor de crianÃas com necessidade de realizaÃÃo de tratamento odontolÃgico submetidas a anestesia local odontolÃgica, com seringa convencional e com seringa controlada por computador (dispositivo). Trinta crian...

  1. AvaliaÃÃo da reaÃÃo do paciente durante a administraÃÃo de anestesia local com seringa convencional ou com controle de punÃÃo

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    Raquel Campelo Ferreira da Costa

    2012-01-01

    A anestesia local, utilizada como procedimento de rotina em Odontologia para permitir a realizaÃÃo de um tratamento indolor, por si jà apresenta algum grau de dor/desconforto ao paciente, contribuindo para aumentar o medo e a ansiedade no tratamento odontolÃgico em crianÃas e adultos. Este trabalho teve como objetivo avaliar a reaÃÃo do paciente durante a anestesia local com seringa convencional e com um dispositivo que controla a punÃÃo inicial da agulha. Para tanto a amostra foi composta po...

  2. Sigmund Freud (1856-1939 e Karl Köller (1857-1944 e a descoberta da anestesia local Sigmund Freud (1856-1939 y Karl Köller (1857-1944 y el Descubrimiento de la anestesia local Sigmund Freud (1856-1939 and Karl Köller (1857-1944 and the Discovery of local anesthesia

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    Almiro dos Reis Jr

    2009-04-01

    Full Text Available JUSTIFICATVA E OBJETIVOS: O entendimento por vezes admitido de que Sigmund Freud teve a intuição de utilizar a cocaína como anestésico local para intervenções cirúrgicas, ou mesmo de que ele tenha tido algum papel na descoberta da anestesia local não é verídico. Os objetivos das pesquisas de Freud eram outros e o verdadeiro realizador da descoberta foi Karl Köller, sobre o que há argumentos irrefutáveis. Diante desses fatos, tem importância histórica o conhecimento correto da questão. CONTEÚDO: O texto refere-se às propriedades há muito conhecidas da cocaína. Recorda dados pessoais, atividades profissionais e científicas de Sigmund Freud e de Karl Köller. Apresenta as pesquisas de Freud sobre efeitos fisiopatológicos observados com a cocaína. Expõe as razões das duras críticas recebidas por Freud diante de conceitos por ele emitidos. Descreve a súbita, porém consciente e justificada idéia de Karl Köller de estudar cientificamente a cocaína como anestésico local em animais e seres humanos. Indica como foram realizadas as pesquisas pioneiras que culminaram com a descoberta da anestesia local por Köller e as duas exposições sobre esta, feitas em Viena. Relata a primeira intervenção cirúrgica oftalmológica sob anestesia local. Comprova a imediata difusão pelo mundo da descoberta que marcou o início da anestesia locorregional. Comenta numerosos documentos comprobatórios da prioridade de Köller na descoberta. Finalmente, menciona as numerosas homenagens recebidas por Köller em várias partes do mundo. CONCLUSÕES: A anestesia locorregional foi iniciada por Karl Köller em 1884, quando ele provou a possibilidade de praticar intervenções cirúrgicas oftalmológicas sem dor utilizando a cocaína como anestésico local. Sigmund Freud realizou muitas pesquisas sobre a cocaína, mas não participou diretamente do importantíssimo feito.JUSTIFICATIVA Y OBJETIVOS: Los que a veces se cree de que Sigmund Freud tuvo

  3. Resultados imediatos da herniorrafia inguinal com anestesia local associada com sedação Immediate results of inguinal hernia repair with local anesthesia associated with sedation

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    Edgar Valente de Lima Neto

    2003-10-01

    Full Text Available OBJETIVO: Avaliar os resultados imediatos da herniorrafia inguinal com anestesia local associada com sedação. MÉTODOS: Foram operados 30 pacientes portadores de hérnia inguinal, sendo 26 (86,6% do sexo masculino e 4 (13,4 do sexo feminino. Os anestésicos utilizados foram lidocaína a 1% e bupivacaína a 0,5% sem adrenalina, tendo sido adicionado 1mL de bicarbonato de sódio para cada 9mL da solução anestésica. A sedação foi realizada com midazolan. As hérnias mais freqüentes, de acordo com a classificação de Nyhus, foram as do tipo I, encontradas em 16 (53,3% pacientes. Praticou-se o reparo da parede posterior a em 17 (56,6% e em 13 (43,2% o reparo com prótese. Para a análise estatística utilizou-se o teste de McNemar para avaliar a correlação entre os escores de dor na escala E.V.A. agrupada. RESULTADOS: Em nenhum paciente houve necessidade de mudança da técnica anestésica. Entre as complicações, observaram-se: 1 (3,3% hematoma; 1 (3,3% sangramento e 1 (3,3% infecção da ferida operatória. A deambulação foi precoce em 28 (93,3% pacientes, assim como a alimentação oral. O tempo de internação médio foi 18 horas, e o escore de dor na escala visual analógica (E.V.A. foi menor ou igual a 3 em 80% dos pacientes. CONCLUSÃO: A anestesia local com sedação é um método seguro, eficaz, com baixos índices de complicações imediatas, e alto índice de satisfação para pacientes selecionados, portadores de hérnia inguinal.PURPOSE: To present the immediate results of the inguinal hernia repair with local anesthesia associated with sedation. METHODS: Thirty patients were operated on of which 26 (86,6% were male. The age varied from 21 to 76, and the average was of 47 years. The anesthetics used were lidocaine and bupivacaine, and the sedation was accomplished with midazolan. RESULTS: Among the complications was observed: 1 (3,3% bruising; 1 (3,3% blood; and 1 (3,3% case of infection of the operative wound. Early rise

  4. Analgesic efficacy of intracapsular and intra-articular local anaesthesia for knee arthroplasty

    DEFF Research Database (Denmark)

    Andersen, L Ø; Husted, H; Kristensen, B B

    2010-01-01

    -articular catheters with 20 ml ropivacaine 0.5% given at 6 h and again at 24 h, postoperatively. Analgesic efficacy was assessed for 3 h after each injection, using a visual analogue score, where 0 = no pain and 100 = worst pain. There was no statistically significant difference between groups. Maximum pain relief...... anaesthetic has similar analgesic efficacy to intra-articular after total knee arthroplasty....

  5. Intra-articular injection of tenoxicam in rats: assessment of the local effects on the articular cartilage and synovium.

    Science.gov (United States)

    Ozyuvaci, H; Bilgic, B; Ozyuvaci, E; Altan, A; Altug, T; Karaca, C

    2004-01-01

    This study investigated the possible local adverse effects of intra-articular administration of tenoxicam in the rat knee joint. A total of 50 rats were given 0.25 ml of a standard preparation of tenoxicam by injection into the right knee joint and 0.25 ml of 0.9% saline solution by injection into the left knee joint as a control. Groups of 10 rats were killed 24 h, 48 h, 7 days, 14 days and 21 days after tenoxicam administration. Two rats were sham operated; one was killed on the first day and the other on the second day after this procedure. All the joints were prepared and sectioned for histological examination. Tissue loss and oedema were observed in the specimens obtained 24 h and 48 h after treatment with tenoxicam. No pathological changes were observed in the 7-day, 14-day and 21-day specimens, or in the control joints. Caution should be exercised when using intra-articular tenoxicam for post-operative analgesia.

  6. Reduced hospital stay and narcotic consumption, and improved mobilization with local and intraarticular infiltration after hip arthroplasty: a randomized clinical trial of an intraarticular technique versus epidural infusion in 80 patients

    DEFF Research Database (Denmark)

    Andersen, Karen Vestergaard; Pfeiffer-Jensen, Mogens; Haraldsted, Viggo

    2007-01-01

    BACKGROUND: Epidural analgesia gives excellent pain relief but is associated with substantial side effects. We compared wound infiltration combined with intraarticular injection of local anesthetics for pain relief after total hip arthroplasty (THA) with the well-established practice of epidural...... infusion. METHODS: 80 patients undergoing elective THA under spinal block were randomly assigned to receive either (1) continuous epidural infusion (group E) or (2) infiltration around the hip joint with a mixture of 100 mL ropivacaine 2 mg/mL, 1 mL ketorolac 30 mg/mL, and 1 mL epinephrine 0.5 mg...... in both groups but significantly reduced in group A after cessation of treatment. Length of stay was reduced by 2 days (36%) in group A compared to group E (p infiltration combined with 1 intraarticular injection can be recommended for patients undergoing THA. Further...

  7. Epilepsia e anestesia

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    Maranhão, Marcius Vinícius Mulatinho; Gomes, Eni Araújo; Carvalho, Priscila Evaristo de

    2011-01-01

    JUSTIFICATIVA E OBJETIVOS: A epilepsia é uma doença neurológica crônica das mais frequentes. Embora a anestesia para portadores de epilepsia seja mais frequente em neurocirurgia, esse grupo de pacientes necessita, da mesma maneira que a população geral, de anestesia para dife rentes procedimentos diagnósticos e terapêuticos. Este artigo visou abordar os aspectos de maior interesse para o anestesiologista na conduta perioperatória do paciente epiléptico submetido à anestesia para procedimentos...

  8. Anestesia tumescente: técnica auxiliar para excisões extensas em cirurgia dermatológica

    OpenAIRE

    Jerry D. Brewer; Randall K. Roenigk

    2010-01-01

    Introdução: A anestesia local é a forma mais comum de anestesia utilizada em cirurgias cutâneas.Alguns pacientes possuem comorbidades que os colocam no grupo de risco para anestesia geral. A anestesia tumescente é uma técnica que consiste na injeção de uma grande quantidade de anestesia diluída local no plano subcutâneo.A anestesia tumescente pode minimizar o desconforto, auxiliar na hemostasia e contribuir para a facilidade do fechamento de grandes defeitos cirúrgicos que, do contrário, apre...

  9. Hernias inguinales bilaterales operadas con anestesia local mediante hernioplastia de Lichtenstein Bilateral inguinal hernias operated on with local anesthesia by Lichtenstein hernioplasty

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    Bárbaro Agustín Armas Pérez

    2009-03-01

    Full Text Available INTRODUCCIÓN. La hernioplastia inguinal bilateral libre de tensión de Lichtenstein es una posibilidad real de tratamiento en pacientes con hernia inguinal bilateral. Este método es en esencia menos costoso para el paciente, la institución y la economía en general, y permite una reincorporación rápida a la sociedad, por lo cual en el presente estudio se presentaron los resultados de este protocolo de tratamiento, con la finalidad de evaluar su efectividad. MÉTODOS. Se realizó un estudio descriptivo transversal con los primeros 38 pacientes operados con la técnica de Lichtenstein mediante anestesia local (técnica combinada de Braun y de Shleider. Los pacientes fueron operados de forma ambulatoria entre enero de 2001 y diciembre del 2007. Se dio el alta en la tarde, si la operación fue en la mañana; y al amanecer del día siguiente, si se operó en la tarde, con el objetivo de evitar la equimosis declive con la movilización precoz. RESULTADOS. Cuatro de los pacientes presentaban hernias recurrentes. El material protésico más empleado fue el polipropileno (86,9 %. Las complicaciones alcanzaron el 9,1 % (referidas no a los 38 pacientes, sino a las 76 hernioplastias; y después de un seguimiento que osciló entre 1 y 36 meses, se presentó un rechazo al material protésico (1,3 % y una recidiva (1,3 %. CONCLUSIONES. Se concluyó que este procedimiento es aplicable a las hernias bilaterales, ya que el estrés, los costos institucionales y las molestias del paciente se reducen, con lo cual demuestra su eficacia.INTRODUCTION. Lichtenstein's tension free bilateral inguinal hernioplasty is a real possibility for treating patients with bilateral inguinal hernia. This method is essentially less expensive for the patient, the institution and the economy in general, and it allows a fast reincorporation to society. Therefore, the results of this treatment protocol were included in the present study aimed at evaluating its effectiveness. METHODS

  10. Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection.

    Science.gov (United States)

    Kim, Sung Rae; Ho, Myoung Jin; Kim, Sang Hyun; Cho, Ha Ra; Kim, Han Sol; Choi, Yong Seok; Choi, Young Wook; Kang, Myung Joo

    2016-01-01

    Piroxicam (PRX), a potent nonsteroidal anti-inflammatory drug, is prescribed to relieve postoperative and/or chronic joint pain. However, its oral administration often results in serious gastrointestinal adverse effects including duodenal ulceration. Thus, a novel cationic nanoparticle (NP) was explored to minimize the systemic exposure and increase the retention time of PRX in the joint after intra-articular (IA) injection, by forming micrometer-sized electrostatic clusters with endogenous hyaluronic acid (HA) in the synovial cavity. PRX-loaded NPs consisting of poly(lactic- co -glycolic acid), Eudragit RL, and polyvinyl alcohol were constructed with the following characteristics: particle size of 220 nm, zeta potential of 11.5 mV in phosphate-buffered saline, and loading amount of 4.0% (w/w) of PRX. In optical and hyperspectral observations, the cationic NPs formed more than 50 μm-sized aggregates with HA, which was larger than the intercellular gaps between synoviocytes. In an in vivo pharmacokinetic study in rats, area under the plasma concentration-time curve (AUC 0-24 h ) and maximum plasma concentration ( C max ) of PRX after IA injection of the cationic NPs were <70% ( P <0.05) and 60% ( P <0.05), respectively, compared to those obtained from drug solution. Moreover, the drug concentration in joint tissue 24 h after dosing with the cationic NPs was 3.2-fold ( P <0.05) and 1.8-fold ( P <0.05) higher than that from drug solution and neutrally charged NPs, respectively. Therefore, we recommend the IA cationic NP therapy as an effective alternative to traditional oral therapy with PRX, as it increases drug retention selectively in the joint.

  11. Dexmedetomidina associada a propofol em sedação durante anestesia local para cirurgia plástica Dexmedetomidina asociada a propofol en sedación durante anestesia local para cirugía plástica Dexmedetomidine/propofol association for plastic surgery sedation during local anesthesia

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    José Roberto Nociti

    2003-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A dexmedetomidina é um novo agonista alfa2-adrenérgico com propriedades potencialmente úteis em anestesia. Este estudo comparativo tem por finalidade observar os efeitos da dexmedetomidina sobre o consumo de propofol e a evolução dos parâmetros cardiovasculares e respiratórios, quando incluída em técnica de sedação durante anestesia local em cirurgia plástica. MÉTODO: Participaram do estudo 40 pacientes do sexo feminino com idades entre 16 e 60 anos, estado físico ASA I ou II, submetidas a cirurgias plásticas eletivas sob anestesia local. Foram distribuídas aleatoriamente em dois grupos de vinte: C (controle e D (dexmedetomidina. Em ambos, a sedação foi obtida com propofol na dose em bolus inicial de 1 mg.kg-1 seguida de infusão contínua em velocidade ajustada para se obter grau de sedação consciente. No grupo D, as pacientes receberam infusão venosa contínua de dexmedetomidina à velocidade de 0,01 µg.kg-1.min-1, concomitante com a de propofol. Foram avaliados: efeito da dexmedetomidina sobre o consumo de propofol; variação dos parâmetros cardiovasculares (PAS, PAD, PAM, FC e respiratórios (SpO2, P ET CO2; qualidade do controle do sangramento per-operatório e características da recuperação pós-anestésica. RESULTADOS: A velocidade média de infusão de propofol foi menor no grupo D (35,2 ± 5,3 µg.kg-1.min-1 do que no grupo C (72,6 ± 8,5 µg.kg-1.min-1. Os valores médios de PAS, PAD e PAM decresceram em relação ao inicial, a partir dos 30 minutos, no grupo D, mantendo-se a seguir estáveis até o final; no grupo C, aumentaram. A FC manteve-se estável no grupo D e aumentou a partir dos 30 minutos no grupo C. O tempo médio para obedecer ao comando de "abrir os olhos" foi menor no grupo D (6,3 ± 2,5 min em relação ao C (8,9 ± 2,7 min. O controle do sangramento per-operatório foi superior no grupo D em relação ao C. CONCLUSÕES: O emprego da dexmedetomidina associada ao

  12. Analgesic efficacy of intracapsular and intra-articular local anaesthesia for knee arthroplasty

    DEFF Research Database (Denmark)

    Andersen, L Ø; Husted, H; Kristensen, B B

    2010-01-01

    The optimal site for wound delivery of local anaesthetic after total knee arthroplasty is undetermined. Sixty patients having total knee arthroplasty received intra-operative infiltration analgesia with ropivacaine 0.2% and were then were randomly assigned to receive either intracapsular or intra...

  13. Efeitos do uso da adrenalina na anestesia local odontológica em portador de coronariopatia Effects of epinephrine in local dental anesthesia in patients with coronary artery disease

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    Ricardo Simões Neves

    2007-05-01

    Full Text Available FUNDAMENTO: A literatura é controversa no que se refere ao uso de vasoconstritores para anestesia local em cardiopatas, havendo preocupação com a indução de descompensação cardíaca. OBJETIVO: Avaliar parâmetros eletrocardiográficos e de pressão arterial durante procedimento odontológico restaurador sob anestesia local com e sem vasoconstritor em portadores de doença arterial coronária. MÉTODOS: Neste estudo foram avaliados 62 pacientes. As idades variaram de 39 a 80 anos (média de 58,7 + 8,8 anos, sendo 51 pacientes (82,3% do sexo masculino. Do total de pacientes, 30 foram randomizados para receber anestesia com lidocaína 2% com adrenalina (grupo LCA e os demais para lidocaína 2% sem vasoconstritor (grupo LSA. Todos foram submetidos a monitorização ambulatorial da pressão arterial e eletrocardiografia dinâmica por 24 horas. Foram considerados três períodos: 1 basal (registros obtidos durante os 60 minutos que antecederam o procedimento; 2 procedimento (registros obtidos desde o início da anestesia até o final do procedimento e 3 das 24 horas. RESULTADOS: Houve elevação da pressão arterial do período basal para o procedimento nos dois grupos quando analisados separadamente; quando confrontados, não apresentaram diferença entre si. A freqüência cardíaca não se alterou nos dois grupos. Depressão do segmento ST > 1 mm não ocorreu durante os períodos basal e procedimento. Arritmias em número superior a 10 por hora estiveram presentes durante o procedimento em sete pacientes (12,5%, sendo quatro (13,8% do grupo que recebeu anestesia sem adrenalina e três (11,1% do grupo com adrenalina. CONCLUSÃO: Não houve diferença em relação a comportamento da pressão arterial, freqüência cardíaca, evidência de isquemia e arritmias entre os grupos. O uso de vasoconstritor mostrou-se seguro dentro dos limites do estudo.BACKGROUND: The use of vasoconstrictors for local anesthesia in patients with coronary heart

  14. Comparison of interscalene brachial plexus block and intra-articular local anesthetic administration on postoperative pain management in arthroscopic shoulder surgery

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    Recep Aksu

    2015-06-01

    Full Text Available BACKGROUND AND OBJECTIVES: In this study, the aim was to compare postoperative analgesia effects of the administration of ultrasound-guided interscalene brachial plexus block and intra-articular bupivacaine carried out with bupivacaine. METHODS: In the first group of patients 20 mL 0.25% bupivacaine and ultrasound-guided interscalene brachial plexus block (ISPB were applied, while 20 mL 0.25% bupivacaine was given via intra-articular (IA administration to the second group patients after surgery. Patients in the third group were considered the control group and no block was performed. Patient-controlled analgesia (PCA with morphine was used in all three groups for postoperative analgesia. RESULTS: In the ISPB group, morphine consumption in the periods between 0-4, 6-12 and 12-24 postoperative hours and total consumption within 24 h was lower than in the other two groups. Morphine consumption in the IA group was lower than in the control group in the period from 0 to 6 h and the same was true for total morphine consumption in 24 h. Postoperative VASr scores in the ISPB group were lower than both of the other groups in the first 2 h and lower than the control group in the 4th and 6th hours (p < 0.05. In the IA group, VASr and VASm scores in the 2nd, 4th and 6th hours were lower than in the control group (p < 0.05. CONCLUSION: Interscalene brachial plexus block was found to be more effective than intra-articular local anesthetic injection for postoperative analgesia.

  15. Nuevos procedimientos en anestesia local en odontología: el sistema Injex® New proceedings in dental anesthesia: the Injex® system

    OpenAIRE

    C Fernández-Canedo; G Machuca

    2004-01-01

    Una de las circunstancias que han contribuido al desarrollo de la odontología en los últimos tiempos ha sido la mejora en las técnicas anestésicas. Sin embargo, el uso de la aguja en la mayor parte de los sistemas de anestesia dental, a pesar de ser un sistema casi indoloro, constituye un problema por la gran cantidad de pacientes que presentan fobias a la misma. Este hecho empeora cuando las poblaciones que han de ser tratadas son niños o pacientes especiales. En esta revisión bibliográfica ...

  16. Broncospasmo durante la anestesia

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    Lincoln de la Parte Pérez

    2003-03-01

    Full Text Available En esta revisión bibliográfica se presentan los factores que contribuyen a la hiperreactividad de las vías aéreas durante la anestesia. Se presenta una actualización de las acciones de los agentes anestésicos empleados en nuestro medio, así como el tratamiento utilizado en esta complicación. El objetivo fundamental es ofrecer a los anestesiólogos, los elementos necesarios para una mejor conducción anestésica de los pacientes con hiperreactividad de las vías aéreas. Se enfatiza además en la importancia de las medidas preventivas y en el tratamiento inmediato que permita contrarrestar esta complicaciónThose factors contributing to hyperreactivity of the airways during anesthesia are presented in this bibliographic review. An updating is made of the action of the anesthetics used in our setting and the treatment given to this complication is explained. The main objective is to provide anesthesiologists with the necessary elements for a better anesthetic conduction of the patients with hyperreactivity of the airways. It is underlined the importance of taking preventive actions and of immediate treatment to face this complication

  17. Efeito colateral da anestesia local subcutânea com vasoconstritores em bovinos Colateral effects of local anesthesia with vasoconstritors in bovine

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    P.C. Soares

    2000-10-01

    Full Text Available In order to study the effects of different local anaesthetics with and without vasoconstritor (epinefrine, 20 adult crossbred cows were used. The following treatments were carried out:T1 - control (bidistilled water; T2 - chloridrate of lidocaine (20 mg/ml with epinephrine (0.005 mg/ml; T3 - chloridrate of lidocaine (20 mg/ml with epinephrine (0.02 mg/ml; T4 - chloridrate of lidocaine (20 mg/ml with epinephrine (0.05 mg/ml; T5 - chloridrate of lidocaine(20 mg/ml; T6 - chloridrate of procaine (22 mg/ml with epinefrine (0.02 mg/ml; T7 - chloridrate of procaine (22 mg/ml. The different solutions were injected, at the same time, into the subcutaneous space of the medial chest line, 10cm apart, of all cows. Observation at the infiltration sites was made 72 hours later, for the presence or not of tissue reaction, as well as lesion degrees. No differences were found among T1, T5, T6, and T7 , which did not cause tissue reaction. On the other hand, lower lesion tissue degrees were found in cows treated with T2 as compared to T3 and T4. It can be concluded that the use of both local anaesthetics alone or chloridrate of procaine with epinefrine are harmless to the skin while chloridrate of lidocaine associated with any concentration of vasoconstritor may give rise to tissue lesions in cattle.

  18. NEUROCIENCIA Y ANESTESIA

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    Antonello Penna S., Dr., MD, PhD

    2017-09-01

    Full Text Available RESUMEN: Uno de los focos principales de la neurociencia es entender las funciones cerebrales superiores y cómo estas son inhibidas de manera reversible por los anestésicos generales. Por ello, la comprensión del mecanismo de acción de estos fármacos, que rutinariamente se utilizan en la práctica clínica, ha permitido avanzar enormemente en entender cómo se integra la información a nivel cerebral para establecer las nuevas memorias, la capacidad de reaccionar al medio externo y las bases de la consciencia. Desde la primera demostración pública exitosa del efecto de los anestésicos generales hasta nuestros días se ha determinado que los anestésicos actúan en bolsillos hidrofóbicos de receptores proteicos localizados en la membrana plasmática de las neuronas corticales y subcorticales, generando una disminución de la excitabilidad de las redes neuronales. Este efecto puede ser evidenciado por registros electroencefalográficos que han permitido registrar en línea el efecto de cada uno de los anestésicos. De este modo, se ha podido establecer que la anestesia es diferente al sueño, más bien corresponde a un coma farmacológico reversible. Sin embargo, pese a todos los avances, aún quedan muchas preguntas por responder, lo cual es el objetivo de las futuras investigaciones. SUMMARY: One of the main focus of neuroscience is to understand the higher brain functions, which are reversibly inhibited by general anesthetics. Therefore, understanding the mechanism of action of these drugs, which are routinely used in clinical practice, has allowed a great advance in how information is integrated in the brain to establish new memories, the ability to react to external environment and the consciousness. Since the first successful public demonstration of the effect of general anesthetics to the present day, it has been determined that anesthetics act on hydrophobic pockets of protein receptors in cortical and subcortical neurons

  19. Citocinas e anestesia

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    João Batista Santos Garcia

    2002-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Vários trabalhos têm abordado as citocinas que podem ser estimuladas e liberadas por lesão cirúrgica, trauma, infecção, inflamação e câncer. Níveis elevados circulantes das citocinas parece ter implicações no aparecimento de complicações e retardo da recuperação pós-operatória de pacientes. O objetivo da presente revisão é resumir as informações hoje disponíveis sobre citocinas. CONTEÚDO: As citocinas são moléculas polipeptídicas produzidas por uma grande variedade de células e parecem não ter função na homeostase, sob condições normais. Esses mediadores são responsáveis por respostas locais ou sistêmicas, gerando alterações imunológicas, metabólicas, hemodinâmicas, endócrinas e neurais. Podem ativar respostas biológicas benéficas, como estimulação da função antimicrobiana, cicatrização de feridas, mieloestimulação e mobilização de substratos. No entanto, a secreção abundante de citocinas está associada a efeitos deletérios como hipotensão arterial, falência de órgãos e morte. CONCLUSÕES: Ao concluir esta revisão, fica evidente que as citocinas desempenham um papel de fundamental importância como mediadores de respostas metabólicas, hormonais, imunológicas e hematológicas, que há potencial terapêutico com o bloqueio de sua expressão e que a anestesia pode interferir de alguma forma na sua ativação. No entanto, muitas perguntas não estão ainda respondidas e estudos devem ser realizados nos próximos anos buscando esclarecer as ações das citocinas não só para a experimentação mas também para a prática clínica.

  20. A pharmacokinetic/clinical approach to postulate a local action of intra-articular xylazine administration in the horse: a preliminary study.

    Science.gov (United States)

    Di Salvo, A; Della Rocca, G; Bazzica, C; Giontella, A; Cagnardi, P; Nannarone, S

    2014-10-01

    The study aims to evaluate whether the analgesic effect of intra-articular (IA) route of xylazine administered to horses following arthroscopic surgery is due to a local or a systemic action. Two connected studies were performed. In the first, 1 mg/kg b.w. of xylazine was injected IA, and blood samples were taken to assess drug systemic absorption. In addition, systemic effects of the drug (sedation, ataxia or reduction of respiratory and cardiac rate) were registered. Control horses injected with saline IA were included in the study to exclude the influence of anaesthesia in the occurrence of these manifestations. In the second study, 1 mg/kg b.w. of xylazine was administered intravenously (i.v.) in healthy horses. Blood samples were collected to determine the concentrations of xylazine, and the same signs of systemic effects of the drug were recorded. By correlating these parameters, a systemic 'no effect' concentration was defined. Pharmacokinetic data after IA administration resulted in some xylazine absorption (bioavailability equal to 58.12%) with values above the systemic 'no effect' concentration. The occurrence of some signs related to systemic effects in horses receiving IA xylazine was significant compared with horses receiving saline. In conclusion, a systemic action of the drug after IA administration cannot be excluded. © 2014 John Wiley & Sons Ltd.

  1. Randomized clinical trial comparing spinal anesthesia with local anesthesia with sedation for loop colostomy closure Ensaio clínico randomizado comparando raquianestesia com anestesia local, associadas à sedação para o fechamento de colostomia em alça

    Directory of Open Access Journals (Sweden)

    Rone Antônio Alves de Abreu

    2010-09-01

    Full Text Available CONTEXT: Recent studies have shown that local anesthesia for loop colostomy closure is as safe as spinal anesthesia for this procedure. OBJECTIVES: Randomized clinical trial to compare the results from these two techniques. METHODS: Fifty patients were randomized for loop colostomy closure using spinal anesthesia (n = 25 and using local anesthesia (n = 25. Preoperatively, the bowel was evaluated by means of colonoscopy, and bowel preparation was performed with 10% oral mannitol solution and physiological saline solution for lavage through the distal colostomy orifice. All patients were given prophylactic antibiotics (cefoxitin. Pain, analgesia, reestablishment of peristaltism or peristalsis, diet reintroduction, length of hospitalization and rehospitalization were analyzed postoperatively. RESULTS: Surgery duration and local complications were greater in the spinal anesthesia group. Conversion to general anesthesia occurred only with spinal anesthesia. There was no difference in intraoperative pain between the groups, but postoperative pain, reestablishment of peristaltism or peristalsis, diet reintroduction and length of hospitalization were lower with local anesthesia. CONCLUSIONS: Local anesthesia plus sedation offers a safer and more effective method than spinal anesthesia for loop colostomy closure.CONTEXTO: Estudos recentes têm demonstrado que a anestesia local para o fechamento de colostomia em alça é tão segura quanto a raquianestesia para estes procedimentos. OBJETIVOS: Comparar os resultados do fechamento de colostomia em alça usando essas duas técnicas. MÉTODOS: Cinquenta pacientes foram randomizados para o fechamento de colostomia em alça sob raquianestesia (n = 25 e anestesia local (n = 25. No pré-operatório, o cólon foi avaliado por colonoscopia e o preparo intestinal foi realizado com solução oral de manitol a 10% e limpeza com solução salina fisiológica através do orifício distal da colostomia. Todos os

  2. Videolaringoscopios en Anestesia Obstétrica

    OpenAIRE

    Acosta Martínez, Jesús

    2016-01-01

    En cualquier escenario, la Vía Aérea Difícil (VAD) es la mayor causa de morbilidad y mortalidad relacionada con la intubación. En el contexto de la anestesia general de la paciente obstétrica, el manejo de la vía aérea toma especial relevancia dada la alta prevalencia de intubaciones dificultosas y/o fallidas, a pesar de los múltiples avances recientes en la materia. Las complicaciones de la anestesia general persisten como causa de mortalidad asociada a la anestesia en las mujeres embaraz...

  3. Desfluorano en la anestesia inhalatoria del perro

    OpenAIRE

    Sánchez Moreno, Ángela Esther

    2011-01-01

    El objetivo de esta tesis es comprobar la validez del desfluorano como agente anestésico inhalatorio en la anestesia general en el perro. Se han estudiado diferentes parámetros cardiorrespiratorios antes y durante la anestesia de 150 animales sometidos a anestesia inhalatoria con este agente para la realización de diversos procedimientos quirúrgicos o diagnósticos. Los animales fueron premedicados con atropina (10 ug/kg IM) y según el sedante empleado se dividieron en dos grupos, Medetomidina...

  4. Análise de custos entre a raquianestesia e a anestesia venosa com propofol associada ao bloqueio perianal local em operações anorretais Cost analysis between spinal and venous anesthesia with propofol associated with local perianal block in anorectal procedures

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    Paulo Gustavo Kotze

    2009-09-01

    Full Text Available RACIONAL: Atualmente cerca de 90% das operações anorretais podem ser realizadas em regime ambulatorial. A técnica anestésica é fator fundamental na busca de menor tempo de internamento e redução de custos nestes procedimentos. Não há consenso na literatura sobre qual o melhor tipo de anestesia para essas operações. OBJETIVO: Comparar os custos da técnica de raquianestesia com bupivacaína 0,5% isobárica com a técnica de anestesia venosa com propofol associada ao bloqueio perianal local com lidocaína a 2% e bupivacaína 0,5% (anestesia combinada em pacientes submetidos a operações anorretais. MÉTODOS: Foram analisados dados de 99 pacientes submetidos à operações anorretais, divididos em dois grupos: grupo I (raquianestesia, composto por 50 pacientes e grupo II (anestesia combinada, composto por 49 pacientes. Foram estudados os procedimentos cirúrgicos, tempo de procedimento anestésico-cirúrgico, tempo de internamento e custos globais de cada paciente. RESULTADOS: Não houve diferença estatística significativa entre os grupos estudados em relação ao tipo de procedimento cirúrgico, sexo, idade e complicações. O tempo médio do procedimento anestésico-cirúrgico, no grupo I foi de 53,1 minutos e de 44,08 minutos no grupo II (P=0,034. O tempo médio de internamento foi de 19,68 horas no grupo I e de 7,08 horas no grupo II (PBACKGROUND: Approximately ninety percent of anorectal surgical procedures are performed in ambulatory basis. The choice of a proper anesthetic technique is important to achieve shorter hospital stay and low costs. There's no evidence in the literature that an ideal type of anesthesia for these procedures exists. AIM: To compare the costs of patients operated with spinal anesthesia (0,5% bupivacaine with combined anesthesia (propofol and local perineal block with 2% lidocaine and 0,5% bupivacaine in anorectal surgical procedures. METHODS: Data from 99 patients submitted to anorectal operations were

  5. Reacción aguda local tras infiltración intraarticular con Synvisc (Hylan GF 20): A propósito de dos casos Acute local reaction to intra-articular infiltration with Synvisc (Hylan GF20): About two cases

    OpenAIRE

    E. Noáin; J.J. Usoz; J. J. Sánchez-Villares; P.J. Lasanta; F.J. González Arteaga

    2003-01-01

    Un segundo escalón en el tratamiento de la artrosis después de los antiinflamatorios no esteroideos son los denominados condroprotectores y la viscosuplementación intraarticular con ácido hialurónico empleado generalmente en la rodilla. Aunque poco frecuente hay descritos casos de artritis inflamatoria transitoria tras su administración intraarticular. El principal problema es el diagnóstico diferencial con una artritis séptica secundaria y sus consecuencias. Se trata de un proceso generalmen...

  6. The efficacy of intra-articular bupivacaine for relief of pain following arthroscopy of the ankle.

    Science.gov (United States)

    Middleton, F; Coakes, J; Umarji, S; Palmer, S; Venn, R; Panayiotou, S

    2006-12-01

    The intra-articular injection of local anaesthetic is frequently used for pain relief after arthroscopy. There is, however, no published evidence of the analgesic effect of bupivacaine in the ankle. In a randomised, double-blind study, 35 patients undergoing arthroscopy of the ankle were allocated to receive intra-articular saline or bupivacaine. Pain was assessed using pain scores and additional analgesic requirements. Intra-articular bupivacaine had a significant analgesic effect in the immediate post-operative period, reducing pain scores and the need for additional analgesics. We recommend the use of intra-articular bupivacaine for post-operative analgesia in ankle surgery.

  7. Sevofluorano en la anestesia general del perro

    OpenAIRE

    Villalobos Núñez, Carmen María

    2002-01-01

    Para la realización de esta Tesis se han recogido datos de anestesias clínicas realizadas con sevofluorano, con el objeto de valorar los efectos de este agente anestésico en el sistema cardiorrespiratorio. Para ello se han recogido diversos parámetros cardiovasculares y respiratorios monitorizados durante toda la técnica anestésica, así como los tiempos de recuperación, con el objetivo de valorar la duración y calidad de la anestesia. El objetivo de esta Tesis es el estudio de validez clínica...

  8. Effectiveness of intra-articular lidocaine injection for reduction of anterior shoulder dislocation: randomized clinical trial Efetividade da injeção intrarticular de lidocaína na redução das luxações anteriores do ombro: ensaio clínico randomizado

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    Marcel Jun Sugawara Tamaoki

    2012-01-01

    Full Text Available CONTEXT AND OBJECTIVE: Shoulder dislocation is the most common dislocation among the large joints. The aim here was to compare the effectiveness of reduction of acute anterior shoulder dislocation with or without articular anesthesia. DESIGN AND SETTING: Prospective randomized trial conducted in Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp. METHODS: From March 2008 to December 2009, 42 patients with shoulder dislocation were recruited. Reductions using traction-countertraction for acute anterior shoulder dislocation with and without lidocaine articular anesthesia were compared. As the primary outcome, pain was assessed through application of a visual analogue scale before reduction, and one and five minutes after the reduction maneuver was performed. Complications were also assessed. RESULTS: Forty-two patients were included: 20 in the group without analgesia (control group and 22 in the group that received intra-articular lidocaine injection. The group that received intra-articular lidocaine had a statistically greater decrease in pain over time than shown by the control group, both in the first minute (respectively: mean 2.1 (0 to 5.0, standard deviation, SD 1.3, versus mean 4.9 (2.0 to 7.0, SD 1.5; P CONTEXTO E OBJETIVO: A luxação do ombro é a mais frequente luxação das grandes articulações. O objetivo foi comparar a efetividade da redução da luxação anterior aguda do ombro, com ou sem anestesia articular. TIPO DE ESTUDO E LOCAL: Ensaio clínico randomizado desenvolvido na Escola Paulista de Medicina - Universidade Federal de São Paulo (EPM-Unifesp. MÉTODOS: De março de 2008 a dezembro de 2009 foram recrutados 42 pacientes com luxação anterior do ombro agudas. Foi comparada a redução de tração e contra-tração com e sem anestesia intra-articular com lidocaína. Como desfecho primário, a dor foi avaliada por meio da escala visual analógica antes da redução e um e cinco minutos após a

  9. Estudo comparativo entre anestesia peridural torácica e anestesia geral em mastectomia oncológica Estudio comparativo entre la anestesia epidural torácica y la anestesia general en mastectomia oncológica Comparative study between thoracic epidural block and general anesthesia for oncologic mastectomy

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    Sérgio D. Belzarena

    2008-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A anestesia peridural torácica é utilizada com freqüência para procedimentos estéticos da mama e há poucos relatos de seu emprego para mastectomias com exploração axilar. O presente estudo comparou a técnica com anestesia geral em operações oncológicas da mama. MÉTODO: Quarenta pacientes foram divididas em dois grupos. No grupo peridural (n = 20 foi realizada peridural torácica com bupivacaína e fentanil associada à sedação com midazolam. O outro grupo (n = 20 recebeu anestesia geral convencional com propofol, atracúrio e fentanil e manutenção com O2 e isoflurano. Registraram-se no intra-operatório duração da operação, necessidade de complementação da anestesia ou da sedação e variáveis hemodinâmicas. No pós-operatório, foram registrados o tempo para alta da sala de recuperação pós-anestésica e hospitalar, a intensidade da dor e o consumo de analgésicos, os efeitos adversos e a satisfação com a técnica anestésica. RESULTADOS: Os grupos foram semelhantes e não houve diferença na duração da operação. Foi necessário complementar a sedação em 100% das pacientes que receberam anestesia peridural e em 15% foi complementada a analgesia com infiltração de anestésico local na axila. Houve maior incidência de hipertensão arterial no grupo da anestesia geral e de hipotensão entre as que receberam peridural. Ocorreu prurido em 55% das pacientes com anestesia peridural. Náusea (30% e vômito (45% foram mais freqüentes entre as que receberam anestesia geral. A analgesia pós-operatória teve melhor qualidade e o consumo de analgésicos foi menor no grupo da anestesia peridural. O período de internação também foi menor. CONCLUSÕES: A técnica peridural tem algumas vantagens com relação à anestesia geral e pode ser considerada uma opção para anestesia em mastectomias oncológicas com esvaziamento axilar.JUSTIFICATIVA Y OBJETIVOS: La anestesia epidural torácica se

  10. Avaliação da analgesia pós-operatória em pacientes submetidos à cirurgia orificial com anestesia local associada ou não à morfina Evaluation of the postoperative analgesia in patients submitted to anorectal surgery with local anesthesia associated or not the morphine

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    Juvenal da Rocha Torres Neto

    2007-03-01

    Full Text Available Ainda não esta comprovada a eficácia dos derivados morfínicos ao nível de receptores opióides periféricos. Estudos procuram demonstrar o poder da droga em interferir na intensidade da dor quando infiltrada em nervos periféricos. Avaliamos, então, a infiltração local de morfina associada à anestesia local em cirurgias orificiais proctológicas. Nesse estudo foram analisados 61 pacientes, independentemente do gênero, sendo divididos aleatoriamente em dois grupos: a um grupo foi associada morfina ao anestésico local enquanto ao outro houve a administração do anestésico local sem a droga morfínica. Os pacientes de ambos os grupos foram submetidos à sedação e analgesia pós-operatória padronizadas. Foram avaliados: a intensidade da dor, a analgesia pós-operatória e a morbidade. A intensidade da dor, no momento de seu surgimento, foi semelhante nos dois grupos; o tempo de analgesia pós-operatória foi maior no grupo em que a morfina foi administrada, entretanto, não se mostrou estatisticamente significativo; as complicações pós-operatórias foram irrelevantes nos dois grupos. Dessa forma, a infiltração local de morfina na região anorretal tem benefícios em relação à analgesia pós-operatória que não mostraram significância estatística e não aumenta a incidência dos efeitos colaterais tão temidos relacionados às drogas morfínicas como retenção urinária e prurido.It has not been proved the efficacy of morphine derived at periphery opium receivers. Studies are trying to demonstrate the power of the drug to interfere in the intensity of surgical pain while infiltrating in the periphery nerves. This study evaluated the infiltration of morphine associated with local anesthesia in anorectal surgery. Sixty one patients were analyzed, male and female, divided in two groups: in one group was associated morphine in the local anesthesia while in the other group only the local anesthetic was used. The patients of both

  11. Open lateral internal anal sphincterotomy under local anesthesia as the gold standard in the treatment of chronic anal fissures: A prospective clinical and manometric study Esfinterotomía lateral interna abierta con anestesia local como gold standard en el tratamiento de la fisura anal crónica: Estudio prospectivo clínico y manométrico a largo plazo

    Directory of Open Access Journals (Sweden)

    A. Sánchez Romero

    2004-12-01

    hipertonía esfinteriana (mecanismo etiopatogénico fundamental de la fisura, permitiendo por tanto, disminuir la proctalgia y así la curación de la fisura. Material y métodos: realizamos un estudio prospectivo de 120 pacientes intervenidos por fisura anal crónica con esfinterotomía lateral interna abierta con anestesia local (20 cc mepivacaína al 2% tratados ambulatoriamente en la consulta de la Unidad de Proctología entre los años 1998-2001. No se requirió estudios preoperatorios, preparación con enemas, profilaxis antibiótica, accesos venosos, ingreso ni observación hospitalaria. Los pacientes fueron revisados a la 1ª semana, 2º mes, 6º mes y al año. Resultados: complicaciones precoces (1ª semana: 3 hematoma-equimosis de la herida (2,5%, 3 hemorragias autolimitadas (2,5%. No encontramos trombosis hemorroidales, fístulas, abscesos perianales ni mortalidad. Complicaciones tardías (2º mes: 9 pacientes con incontinencia (7,5% y 3 pacientes (2,5% con recurrencia de la fisura. Al 6º mes, la incontinencia disminuyó al 5% (6 pacientes, y aparecieron 3 pacientes más con recurrencia de la fisura (2,5%. Al año se mantuvo la tasa de incontinencia del 5% (a gases y líquidos y aparecieron otros 3 pacientes con recurrencia de la fisura (2,5%. Recurrencia global del 7,5%. Los hallazgos en la manometría fueron, PMB (presión máxima basal pre-tratamiento similar a la PMB en pacientes con recurrencia de la fisura, así como la PMB del grupo control similar a la PMB de pacientes con curación. La PMB en pacientes incontinentes fue más baja que la PMB en pacientes continentes (55 ± 7 frente a 80,7 ± 21. La diferencia entre la PMCV (presión máxima de contracción voluntaria en pacientes incontinentes y pacientes continentes no fue estadísticamente significativa. Conclusiones: la esfinterotomía lateral interna abierta con anestesia local tiene una tasa de curación a largo plazo y unos índices de morbilidad equiparables a otras técnicas, por lo que puede

  12. Intraarticular osteochondroma of the knee

    Directory of Open Access Journals (Sweden)

    Vivek Machhindra Morey

    2014-01-01

    Full Text Available Osteochondromas are usually extra articular and grow away from the joint towards the diaphysis. Intraarticular osteochondromas are very rare and often misdiagnosed. We report a case of 16-year-old boy who presented with pain and clicking sound in the right knee for last 6 months. On examination, click was felt at the terminal flexion of the knee. The lateral radiograph of the right knee showed a radio opaque shadow at the posterior aspect of the distal end of femur, which was further evaluated with an MRI. Arthroscopy showed a hard lesion arising from the roof of the intercondylar notch of femur. It was excised arthroscopically. Histopathology revealed it to be an osteochondroma. Thus, intraarticular osteochondroma of the knee can be considered as a rare cause of pain in young patients.

  13. ANESTESIA FUERA DE PABELLÓN

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    Andrés Leiva, Dr.

    2017-09-01

    Full Text Available RESUMEN: La implementación de nuevos procedimientos diagnósticos y terapéuticos realizados fuera de pabellón ha crecido ampliamente en las últimas décadas. Esto ha generado un desafío para los anestesiólogos quienes han debido adaptar su quehacer, interactuando con múltiples especialidades médicas y en lugares no diseñados inicialmente para proveer anestesia. La diversidad de procedimientos y de pacientes involucran todo el espectro anestésico, desde los cuidados anestésicos monitorizados hasta la anestesia general. Las complicaciones reportadas son las mismas que aquellas ocurridas en el ámbito quirúrgico, siendo las que implican el manejo de la vía aérea las de mayor incidencia. Mantener estándares de calidad similares a los proporcionados a los pacientes quirúrgicos habituales, junto con la capacitación frecuente de todo el personal involucrado e implementación y cumplimiento de guías que identifiquen los riesgos y los aspectos únicos de esta actividad resultará clave en disminuir la ocurrencia de eventos adversos y la severidad del daño causado. SUMMARY: New diagnostic and therapeutic procedures performed outside the operating room has grown widely in recent decades. This has involved a challenge for anesthesiologists who have had to adapt their work, interacting with multiple medical specialties and in places not initially designed to provide anesthesia. The diversity of procedures and patients involve the entire anesthetic spectrum from monitored anesthetic care to general anesthesia. The reported complications are the same as those occurred in the surgical setting, being those involving airway management the ones with the highest incidence. Maintaining standards of quality, similar to provided in regular surgical patients, frequent training of all staff involved and the implementation and compliance of guidelines that identify the risks and unique aspects of this activity, will be key in reducing the occurrence of

  14. Anestesia extra-dural en el parto

    Directory of Open Access Journals (Sweden)

    Alberto Cárdenas Escobar

    1956-05-01

    Full Text Available Desde que A. J. Corning practicó en 1885 la primera inyección de una solución de cocaína en el espacio epidural, diversos métodos anestésicos que utilizan este espacio han sido ensayados, tanto en cirugía como en obstetricia. Sicard y Cathelin, en 1901, usaron el hiatus sacro para anestesia epidural en operaciones urológicas. Stoeckel y Schlimpert en 1911 fueron los primeros en emplear este método en obstetricia. Reemplazaron la cocaína por novocaína. recientemente preparada, y lograron analgesia bastante satisfactoria durante 30 minutos a 1 hora, en casos seleccionados

  15. Falhas na anestesia subaracnóidea Fallos en la anestesia subaracnoide Failure of subarachnoid blocks

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    Hugo Praxedes

    2010-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Desde Bier, é descrita falha de anestesia subaracnóidea que causa desconforto ao paciente e que ocorre, eventualmente, mesmo diante de profissionais hábeis que a tenham conduzido de forma tecnicamente correta. Há variação, no entanto, de conceito de falha e, principalmente, de identificação precisa de causas. O objetivo do trabalho é identificar melhor as causas deste desconforto por meio de revisão sistemática de publicações com casuística significativa. CONTEÚDO: Dividiu-se a análise em três tópicos: anatomia e suas variações; o agente anestésico, que trata da seleção do agente, suas soluções e adições, de forma a atingir o resultado mais apropriado à intervenção cirúrgica proposta; e a dose, discutindo-se concentração, volume ou dose gravimétrica, no sentido de obter resultado mais adequado tanto no que diz respeito à intensidade do bloqueio quanto à sua duração. CONCLUSÕES: As falhas são mais afeitas a fatores técnicos: avaliação anatômica adequada, escolha criteriosa da agulha e do local da punção, cuidados no armazenamento dos agentes, adequação de dose, baricidade, além de posicionamento correto do paciente durante e após punção, tudo adequado ao objetivo cirúrgico.JUSTIFICATIVA Y OBJETIVOS: Bier ya describía los fallos en la anestesia subaracnoidea que causa la incomodidad al paciente, y que se da, eventualmente, incluso con la presencia de profesionales hábiles que la hayan conducido de forma técnicamente correcta. Existe una variación, sin embargo, del concepto de fallo y principalmente, de la identificación precisa de las causas. El objetivo del trabajo es identificar mejor las causas de esa incomodidad a través de la revisión sistemática de publicaciones con casuística significativa. CONTENIDO: El análisis se dividió en tres tópicos: la anatomía y sus variaciones; el agente anestésico, que trata sobre la selección del agente, sus soluciones

  16. The risk of intraarticular injections are overestimated

    DEFF Research Database (Denmark)

    Asmussen, Rikke; Just, Søren Andreas; Jensen Hansen, Inger Marie

    The risk of intraarticular injections are overestimated. Volume 73, Annals of the Rheumatic Diseases, the EULAR Journal,, June 2014 volume 73, supplement 2, p. 286-87......The risk of intraarticular injections are overestimated. Volume 73, Annals of the Rheumatic Diseases, the EULAR Journal,, June 2014 volume 73, supplement 2, p. 286-87...

  17. Herniorrafia inguinal com anestesia locorregional - (uso de ropivacaína

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    James Skinovsky

    Full Text Available OBJETIVO: O objetivo deste estudo é relatar a eficiência e a segurança da realização de herniorrafias inguinais com a utilização da anestesia locorregional com ropivacaina, destacando sua técnica, suas indicações e limitações. MÉTODO: Foram operados 50 pacientes, no período compreendido entre janeiro e dezembro de 2005, sendo submetidos à herniorrafia inguinal mediante anestesia locorregional utilizando-se o anestésico ropivacaina, associada a sedação intra-venosa, no Hospital Universitário Cruz Vermelha Brasileira - UnicenP, na cidade de Curitiba-PR, sendo utilizada técnica sem tensão, com o uso de prótese. Foram avaliadas as variáveis idade, gênero e tipo de hérnia através da classificação de Nyhus. RESULTADOS: Não foram observadas quaisquer alterações conseqüentes a reações adversas ao anestésico local, não sendo necessária nenhuma conversão do método anestésico ou mesmo complementação deste. As complicações pós-operatórias foram de pequena monta e de resolução adequada. CONCLUSÃO: A anestesia local por bloqueio de campo, com o uso de ropivacaína e associada a sedação intravenosa, para a realização de herniorrafias inguinais, constitui-se em procedimento plenamente viável, prático, menos oneroso e benéfico ao paciente.

  18. Historia de la Anestesia en Colombia

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    Efraím Otero-Ruiz

    2000-08-01

    Full Text Available

    Con el patrocinio de la Sociedad Colombiana de Anestesiología y Reanimación (SCARE y pulcramente editado por Gente Nueva Editorial, en Julio de 1999 ha publicado el Académico Jaime Herrera Pontón su volumen “Historia de la Anestesia en Colombia“, aparecido justamente con motivo de los 50 años de fundación de dicha Sociedad.

    El volumen, de pasta dura y de 300 páginas, con prólogo de Luis Duque Gómez, Presidente de la Academia Colombiana de Historia e ilustrado con numerosas fotografías, está dividido en 14 capítulos y 3 apéndices, precedidos de una introducción a cargo del autor.

    Los 4 primeros capítulos, desde la conquista y la colonia hasta los primeros decenios de nuestra república, describen las primeras plantas sedantes y analgésicas nativas lo mismo que los primeros venenos paralizantes empleados por nuestros aborígenes, el opio empleado como profundo analgésico en nuestras guerras emancipadoras y la creación de los primeros programas de estudios médicos en Colombia. De ahí arrancan dos extensos capítulos, pivotales en el desarrollo de esta historia: el 50., titulado “El siglo XIX desde la primera demostración del éter” y el 60. “El siglo XX hasta la creación de la Sociedad Colombiana de Anestesia”. En ellos se describen de manera más o menos suscinta los primeros esfuerzos para diferenciar las técnicas anestésicas de las quirúrgicas propiamente dichas y el lento pero prodigioso esfuerzo por hacer de la anestesiología una especialidad médica, fenómeno que no sucede hasta bien entradas la 4a. y 5a. décadas del pasado siglo. Esos primeros cien años, como sucede en el resto del mundo occidental, estarán dominados por el éter y el cloroformo en método abierto ya que otros agentes, como el etileno y el ciclopropano, apenas comienzan a llegar en vísperas de la lIa. Guerra Mundial, lo mismo que los primeros aparatos de circuito cerrado, la inducción por barbitúricos intravenosos y

  19. On the main stages of the history of intra-articular therapy

    Directory of Open Access Journals (Sweden)

    L. Punzi

    2011-09-01

    Full Text Available In this review the main stages in the history of intra-articular therapy of the rheumatic diseases are summarized. The first approach to such a local treatment has been likely performed in 1792 by the French physician Jean Gay, who injected in a swelling knee the “eau du Goulard” (Goulard’s water, namely a mixture based on lead compounds. In the XIX century iodine derivatives have been mainly applied as an intra-articular treatment. In the XX century, before the wide use of intra-articular corticosteroids, chiefly due to the Joseph Lee Hollander’s experiences, a variety of drugs has been employed, including cytostatics and sclerosing substances. A further important stage has been synoviorthesis, by using specific radionuclides, that would actually represent an anti-synovial treatment. In the last years a spread use of intra-articular hyaluronic acid, particularly in osteoarthritis, has been recorded, with the aim to warrant articular viscosupplementation. Future of intra-articular treatment should be represented by the biological drugs, i.e., anti-TNF, but it is still untimely to define the exact role of such a local treatment of arthritis.

  20. Corresponsales nacionales y extranjeros: adelantos recientes en la anestesia general

    OpenAIRE

    Gómez Martínez, Pablo

    2011-01-01

    Bajo este título he procurado resumir y traducir una conferenciaque hace poco dictó el doctor H. Lieber, al curso de especialización en Cirugía para médicos graduados que se dicta en la Universidad de Nueva York. Teoria. La bioquímica de la anestesia no ha sido dilucidada claramente todavía. Dos teorías se acomodan bastante bien con los hechos y han servido para hacer avanzar la anestesia práctica. Me prometo discutir las teorías de una manera general; para detalles, consúltense los escritos ...

  1. Anestesia en la ventana aorto-pulmonar

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    Lincoln de la Parte Pérez

    2001-06-01

    Full Text Available Se realiza un estudio retrospectivo de 9 niños menores de 2 años operados de ventana aorto-pulmonar en el Cardiocentro del Hospital Pediátrico Docente "William Soler", durante el período de 1986 a 1994. El fentanyl fue el agente más utilizado en la inducción de la anestesia (8 pacientes, 89 % y se empleó en todos los pacientes durante el mantenimiento, lo que aportó gran estabilidad hemodinámica. Las complicaciones encontradas fueron el síndrome de bajo gasto cardíaco, broncoespasmo, hipertensión pulmonar y arritmias cardíacas. En todos los pacientes se utilizó el protocolo para el manejo de la hipertensión pulmonar. No hubo fallecidos durante el transoperatorio ni en el posoperatorio inmediato.A retrospective study of 9 children under 2 operated on of aorto-pulmonary window at the Heart Center of "William Soler" Pediatric Teaching Hospital from 1986 to 1994 was conducted. Fentanyl was the most used agent in the induction of anesthesia (8 patients, 89 % and it was administered to all patients during maintenance, which made possible a great hemodynamic stability. The complications found were the syndrome of low cardiac output, bronchospasm, pulmonary hypertension and cardiac arrhythmias. The protocol for the management of pulmonary hypertension was used with all patients. Deaths were not reported either during the transoperative or in the immediate postoperative.

  2. Clinical characteristics of pain originating from intra-articular structures of the knee joint in patients with medial knee osteoarthritis

    OpenAIRE

    Ikeuchi, Masahiko; Izumi, Masashi; Aso, Koji; Sugimura, Natsuki; Tani, Toshikazu

    2013-01-01

    Purpose Although disease progression of osteoarthritis has been well documented, pain pathophysiology is largely unknown. This study was designed with two purposes: 1) to characterize patients with knee pain predominantly originating from intra-articular structures and 2) to describe the location and pattern of their pain. Materials and methods 103 patients with medial knee osteoarthritis underwent an intra-articular injection of local anesthetics (joint block). At least 70% pain relief was d...

  3. Anestesia para cesariana em paciente com siringomielia lombar

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    Lakshmi Jayaraman

    2011-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Siringomielia é uma condição neurológica incomum caracterizada pela presença de uma cavidade cística expansiva na medula espinhal, resultando em várias manifestações neurológicas. O objetivo deste relato de caso é destacar a segurança da anestesia geral nesse grupo de pacientes. RELATO DO CASO: Primigesta de 28 anos, com diagnóstico de siringomielia lombar, foi programada para cirurgia de cesareana (CC. A cirurgia foi realizada sob anestesia geral, sem complicações. A anestesia geral foi escolhida no caso dessa paciente para evitar qualquer manipulação do espaço subaracnoideo no bloqueio do neuroeixo central, o que poderia levar a alterações da pressão intracraniana ou agravamento de sintomas neurológicos. Foi utilizado rocurônio, considerando que evita aumento de pressão no líquido cefalorraquidiano e hipercalemia, que podem ser vistos com succinilcolina. CONCLUSÕES: A anestesia geral pode ser usada com segurança em pacientes portadores de siringomielia. Devem-se tomar precauções para evitar aumento da pressão intracraniana e o bloqueio neuromuscular deve ser monitorado.

  4. Early osteoarthritis and microdialysis: a novel in vivo approach for measurements of biochemical markers in the perisynovium and intraarticularly

    DEFF Research Database (Denmark)

    Helmark, Ida Carøe; Mikkelsen, U R; Krogsgaard, M R

    2010-01-01

    The microdialysis technique was evaluated as a possible method to obtain local measurements of biochemical markers from knee joints with degenerative changes. Seven patients scheduled for arthroscopy of the knee due to minor to moderate degenerative changes had microdialysis catheters inserted...... intraarticular catheters and 6/7 subsynovial catheters were positioned correctly. Relative recovery (RR) was intraarticularly 0.64 ± 0.02 (mean ± SEM) and synovium-close 0.54 ± 0.06. Mean values of cartilage oligomeric matrix protein (COMP), aggrecan and glucosyl-galactosyl-pyridinoline in the intraarticular...... dialysates were 18.1 ± 7.0 U/l, 243.6 ± 108.6 ng/ml and 108.0 ± 29.0 pmol/ml, respectively. COMP and glucosyl-galactosyl-pyridinoline concentrations were significantly higher intraarticularly compared to perisynovial tissue (P

  5. Incidência de tremor em anestesia peridural com ou sem fentanil: estudo comparativo

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    Abreu Múcio Paranhos de

    2004-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A maioria dos trabalhos encontrados na literatura, relacionando a influência dos opióides administrados por via peridural com o tremor intra e pós-operatório, foram realizados com grupos de pacientes obstétricas, nas quais a resposta do centro termorregulador pode ser diferente das pacientes não grávidas. O objetivo deste trabalho foi comparar o bloqueio peridural com e sem fentanil, quanto à incidência de tremores e outras complicações no intra e pós-operatório em pacientes submetidos à cirurgia de varizes sob anestesia peridural com bupivacaína a 0,5% com adrenalina a 1:200.000. MÉTODO: Trinta e quatro pacientes, estado físico ASA I e II, submetidos à cirurgia para tratamento de varizes de membros inferiores, foram divididos aleatoriamente em 2 grupos (n = 17, e receberam midazolam (0,05 mg.kg-1, por via venosa seguido de anestesia peridural lombar, utilizando-se no grupo S, 20 ml bupivacaína a 0,5% (com vasoconstritor associado a 2 ml de solução fisiológica a 0,9% e no grupo F, 20 ml de bupivacaína a 0,5% (com vasoconstritor associada ao fentanil (100 µg. Foram estudados: incidência de tremor, temperatura dos pacientes, necessidade do uso de meperidina, e a incidência de náuseas e vômitos nos seguintes momentos: M1 - admissão do paciente na sala de operação; M2 - imediatamente antes da anestesia; M3 - 30 minutos após o término da injeção do anestésico local; M4 - 60 minutos após o término da injeção do anestésico local; M5 - 90 minutos após o término da injeção do anestésico local; M6 - final da anestesia; M7 - antecedendo a alta da sala de recuperação pós-anestésica. RESULTADOS: Quanto aos dados antropométricos, estado físico, tempo médio de duração da anestesia e cirurgia, temperatura dos pacientes e da sala de operação e incidência de náuseas e vômitos não houve diferença estatística entre os grupos. Houve diferença estatística aos 60 minutos (M4 e

  6. ¿QUÉ HACEMOS LOS ANESTESIÓLOGOS? DESDE LA VIGILANCIA ANESTÉSICA MONITORIZADA HASTA LA ANESTESIA GENERAL

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    Ricardo Bustamante, Dr.

    2017-09-01

    Full Text Available RESUMEN: La anestesiología es la rama de la medicina dedicada al alivio del dolor y al total cuidado del paciente antes, durante y después de un acto quirúrgico. Es una de las especialidades de la medicina que más ha avanzado en los últimos 40 años. Es así que hoy se operan pacientes que nunca se hubiera pensado que podrán operarse, llegando a cifras de mortalidad por causa anestésica bajísimas.Los anestesiólogos administran diferentes tipos de anestesia: desde la vigilancia del paciente despierto o con diversos grados de sedación, sin anestesia o con anestesia local, hasta la realización de variados tipos de bloqueos periféricos, bloqueos neuroaxiales o diferentes tipos de anestesia general (inhalatoria, endovenosa total o una mezcla de ambas.La actividad del anestesiólogo se ha extendido a muchas actividades fuera del pabellón quirúrgico, especialmente a procedimientos radiológicos, hemodinámicos, oncológicos, endoscópicos y dentales.Con el tiempo, se han desarrollado algunas subespecialidades en la anestesiología: cuidados intensivos, dolor crónico, anestesia pediátrica, anestesia cardiovascular, anestesia obstétrica, cuidados paliativos anestesia regional. Algunas actividades de la medicina los anestesiólogos las comparten con otros especialistas. Las más comunes son la medicina intensiva, el manejo del dolor crónico y los cuidados paliativos.Otra especialidad multidisciplina, que está surgiendo e instalándose en la medicina moderna es la medicina perioperatoria. La mayoría de los anestesiólogos practican en cierto grado la medicina perioperatoria y constituye probablemente el futuro de la anestesia, si es que nuestra especialidad desea prosperar. SUMMARY: Anesthesiology is the branch of medicine dedicated to relieve pain and total patient care before, during and after a surgical procedure. It is one of the medical specialties that has advanced

  7. Intra-articular therapies for osteoarthritis.

    Science.gov (United States)

    Yu, Shirley P; Hunter, David J

    2016-10-01

    Conventional medical therapies for osteoarthritis are mainly palliative in nature, aiming to control pain and symptoms. Traditional intra-articular therapies are not recommended in guidelines as first line therapy, but are potential alternatives, when conventional therapies have failed. Current and future intra-articular drug therapies for osteoarthritis are highlighted, including corticosteroids, hyaluronate, and more controversial treatments marketed commercially, namely platelet rich plasma and mesenchymal cell therapy. Intraarticular disease modifying osteoarthritis drugs are the future of osteoarthritis treatments, aiming at structural modification and altering the disease progression. Interleukin-1β inhibitor, bone morphogenic protein-7, fibroblast growth factor 18, bradykinin B2 receptor antagonist, human serum albumin, and gene therapy are discussed in this review. The evolution of drug development in osteoarthritis is limited by the ability to demonstrate effect. High quality trials are required to justify the use of existing intra-articular therapies and to advocate for newer, promising therapies. Challenges in osteoarthritis therapy research are fundamentally related to the complexity of the pathological mechanisms of osteoarthritis. Novel drugs offer hope in a disease with limited medical therapy options. Whether these future intra-articular therapies will provide clinically meaningful benefits, remains unknown.

  8. O alvorecer da anestesia inalatória: uma perspectiva histórica El alborear de la anestesia inhaladora: una perspectiva histórica Dawning of inhalational anesthesia: a historical perspective

    Directory of Open Access Journals (Sweden)

    R icardo Jakson de Freitas Maia

    2002-11-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A história, ao contrário do que muitos imaginam, não é algo limitado ao passado e de caráter imutável. Ela sofre adaptações de acordo com as conveniências de uma ou outra classe social dominante. Informações que foram ocultadas, deliberadamente ou não, uma vez descobertas, poderão mudar conceitos atuais, até então estabelecidos como verdadeiros. Sendo assim, a história, como qualquer outra ciência, não é totalmente imparcial; sofre influências e interferências de forças de natureza política, religiosa, econômica e cultural. Com a História da anestesia não é diferente. Algumas questões permanecem intrigantes: Por que se levou tanto tempo para a civilização controlar a dor? Quem realmente descobriu a Anestesia? Como era o mundo quando se deu a descoberta oficial da Anestesia? Para refletir sobre tais perguntas faz-se necessário recorrer à História da Anestesia. CONTEÚDO: O texto aborda o ato cirúrgico, a dor e a anestesia desde a cultura helênica até a primeira anestesia oficialmente reconhecida, destacando nomes freqüentemente esquecidos e as peculiaridades históricas que beneficiaram ou prejudicaram um ou outro descobridor. Também enfoca os valores, a cultura e o desenvolvimento científico no século XIX, correlacionando-os com os eventos que marcaram o advento da anestesia. CONCLUSÕES: Não seria justo atribuir o mérito da descoberta da anestesia a uma única pessoa. As peculiaridades históricas que beneficiaram ou prejudicaram um ou outro pesquisador não podem ser esquecidas. Morton foi sem dúvidas o mais agraciado pelas circunstâncias. Viveu no tempo e local privilegiados, e conviveu com as pessoas mais apropriadas ao seu intento. Todavia uma questão persiste. Afinal, quem é o mais importante: o pai da idéia ou aquele que a divulgou? A resposta certamente cairá no campo da subjetividade.JUSTIFICATIVA Y OBJETIVOS: La historia, al contrario de lo que muchos se

  9. The comparison effects of intra-articular injection of different opioids on postoperative pain relieve after arthroscopic anterior cruciate ligament reconstruction: A randomized clinical trial study

    Directory of Open Access Journals (Sweden)

    Hamidreza Arti

    2011-01-01

    Conclusions: Administering 5 mg intra-articular morphine after arthroscopic ACL reconstruction is a valuable choice and is recommended to be added to other local anesthetics administrated drugs after this procedure.

  10. The effect of intra-articular hyaluronate and tramadol injection on patients with adhesive capsulitis of the shoulder.

    Science.gov (United States)

    Kim, Kyung-Hee; Suh, Jung-Woo; Oh, Ki Young

    2017-08-03

    Local administration of opioids causes effective analgesia without adverse effects related to the central nervous system. After the beneficial demonstration of peripheral opioid receptors in joint synovia, intra-articular opioid injections were used for pain treatment. Clinical studies have reported the safety and efficacy of hyaluronate injection in the shoulder joint of patients with osteoarthritis, periarthritis, rotator cuff tears, and adhesive capsulitis. To estimate the efficacy of intra-articular hyaluronate and tramadol injection for adhesive capsulitis of the shoulder compared with that of intra-articular hyaluronate injection alone. Thirty patients with adhesive capsulitis of the shoulder were randomized to the hyaluronate group (n= 16) or the tramadol group (n= 14). Hyaluronate group members were administered five weekly intra-articular hyaluronate injections; tramadol group members were administered three weekly intra-articular hyaluronate and tramadol injections and then two weekly intra-articular injections of hyaluronate. Visual Analog Scale (VAS), passive range of motion (PROM) of the shoulder joint, and Shoulder Pain and Disability Index (SPADI) scores were assessed at baseline and weeks 1, 2, 3, 4, and 6 after the initial injection. A significant improvement was observed in VAS, PROM, and SPADI scores between time points in both groups. In comparison in both groups at weeks 1 and 2 after the initial injection the VAS scores of the tramadol group were significantly lower than those of the hyaluronate group. Intra-articular hyaluronate with tramadol showed more rapid and strong analgesic effects than intra-articular hyaluronate alone and did not induce any adverse effects.

  11. Symposium: evidence for the use of intra-articular cortisone or hyaluronic acid injection in the hip

    Science.gov (United States)

    Chandrasekaran, Sivashankar; Lodhia, Parth; Suarez-Ahedo, Carlos; Vemula, S. Pavan; Martin, Timothy J.; Domb, Benjamin G.

    2016-01-01

    The primary purpose of this review article is to discuss the role of diagnostic, corticosteroid, hyaluronic acid (HA) and platelet rich plasma (PRP) in the treatment of osteoarthritis (OA) and femoroacetabular impingement (FIA). These treatments play an important biological role in the non-operative management of these conditions. Two independent reviewers performed an search of PubMed for articles that contained at least one of the following search terms pertaining to intra-articular hip injection—local anaesthetic, diagnostic, ultrasound, fluoroscopic, image guided, corticosteroid, HA, PRP, OA, labral tears and FAI. Seventy-two full text articles were suitable for inclusion. There were 18 articles addressing the efficacy of diagnostic intra-articular hip injections. With respect to efficacy in OA there were 25 articles pertaining to efficacy of corticosteroid, 22 of HA and 4 of PRP. There were three articles addressing the efficacy of biologics in FAI. Diagnostic intra-articular hip injections are sensitive and specific for differentiating between intra-articular, extra-articular and spinal causes of hip symptoms. Ultrasound and fluoroscopy improves the precision of intra-articular positioning of diagnostic injections. Corticosteroids are more effective than HA and PRP in alleviating pain from hip OA. A higher dose of corticosteroids produces a longer benefit but volume of injection has no significant effect. Intra-articular corticosteroids do not increase infection rates of subsequent arthroplasty. There is currently limited evidence to warrant the routine use of therapeutic injections in the management of labral tears and FIA. PMID:27026814

  12. Espondilite anquilosante e anestesia Espondilitis anquilosante y anestesia Ankylosing spondylitis and anesthesia

    Directory of Open Access Journals (Sweden)

    Carlos Rogério Degrandi Oliveira

    2007-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A espondilite anquilosante (EA é uma doença inflamatória crônica das articulações, incluída no grupo das espondiloartropatias soronegativas. A característica principal dessa doença é a fusão óssea da coluna vertebral que leva à perda permanente da flexibilidade do dorso e do pescoço. Outras grandes articulações e tecidos conectivos poderão estar afetados pelo processo inflamatório. A EA acomete principalmente homens entre 20 e 40 anos; é rara após os 50 anos. As mulheres correspondem somente à minoria de pacientes. Há pouca informação sobre a EA na literatura anestésica. O objetivo deste artigo foi revisar aspectos da EA de interesse para o anestesiologista, permitindo um adequado manuseio perioperatório. CONTEÚDO: Estão definidas as características da espondilite anquilosante quanto à clínica e a conduta anestésica. CONCLUSÕES: Os pacientes com doenças crônicas da coluna vertebral apresentam desafios específicos para o anestesiologista. O manuseio da via aérea e o acesso ao neuroeixo poderão ser difíceis. Preferência tem sido dada à anestesia geral, mesmo com via aérea difícil reconhecida, evitando-se a anestesia no neuroeixo. O grau de envolvimento da coluna cervical determinará o quanto poderá ser difícil a intubação traqueal. Cuidado especial deve ser tomado para evitar a manipulação excessiva da coluna cervical, que poderia levar ao trauma da medula espinhal.JUSTIFICATIVA Y OBJETIVOS: La espondilitis anquilosante (EA es una enfermedad inflamatoria crónica de las articulaciones, incluida en el grupo de las espondiloartropatías soronegativas. La característica principal de esa enfermedad es la fusión ósea de la columna vertebral que conlleva a la pérdida permanente de la flexibilidad del dorso y del cuello. Otras grandes articulaciones y tejidos conectivos podrán estar afectados por el proceso inflamatorio. La EA acomete principalmente a hombres entre los 20 y

  13. Meningitis tras anestesia espinal Meningitis after a spinal anesthesia

    OpenAIRE

    A. L. Vázquez-Martínez; F. Castro; G. Illodo; E. Freiré; M. A. Camba

    2008-01-01

    La meningitis post-punción es una importante complicación de la anestesia espinal. Describimos el caso de un varón de cuarenta y seis años que ingresó para tratamiento quirúrgico de una hernia umbilical, la cirugía se realizó bajo anestesia intradural. Tras la intervención el paciente comenzó con un cuadro clínico compatible con meningitis, que se confirmó tras examen del líquido cefalorraquídeo. Se trató con antibióticos a pesar de la no identificación de gérmenes, siendo la evolución favora...

  14. Espondilodiscitis secundaria a anestesia peridural Spondilodiscitis secondary to peridural anesthesia

    OpenAIRE

    Yvei González Orlandi; Luis Elizondo Barriel; Reinel Junco Martín; Jorge Rojas Manresa; Victor Duboy Limonta; Federico Córdova Armengol

    2010-01-01

    Se presenta el caso de un paciente con espondilodiscitis secundaria al uso de anestesia peridural lumbar para la resección transuretral de una hiperplasia fibroadenomatosa de la próstata. El cuadro clínico estuvo determinado por lumbalgia aguda con incremento progresivo que llevó al confinamiento en cama del paciente. En el examen físico del sistema osteomioarticular predominó la contractura paravertebral lumbar, así como en la palpación de esta región. En el examen neurológico no se encontra...

  15. Dexmedetomidina: papel atual em anestesia e cuidados intensivos

    OpenAIRE

    Afonso, Joana; Reis, Flávio

    2012-01-01

    JUSTIFICATIVA E OBJETIVOS: Atualizar e rever a aplicação da dexmedetomidina em anestesia e cuidados intensivos. Este trabalho é uma revisão abrangente dos usos clínicos, farmacologia, farmacocinética, mecanismo de ação e efeitos adversos da dexmedetomidina. CONTEÚDO: O uso efetivo de agentes sedativo-hipnóticos e analgésicos é parte integral do conforto e segurança dos pacientes. A dexmedetomidina é um potente e altamente seletivo agonista dos adrenoceptores α-2 com propriedades simpaticolíti...

  16. Dexmedetomidina: papel atual em anestesia e cuidados intensivos

    OpenAIRE

    Afonso,Joana; Reis,Flávio

    2012-01-01

    JUSTIFICATIVA E OBJETIVOS: Atualizar e rever a aplicação da dexmedetomidina em anestesia e cuidados intensivos. Este trabalho é uma revisão abrangente dos usos clínicos, farmacologia, farmacocinética, mecanismo de ação e efeitos adversos da dexmedetomidina. CONTEÚDO: O uso efetivo de agentes sedativo-hipnóticos e analgésicos é parte integral do conforto e segurança dos pacientes. A dexmedetomidina é um potente e altamente seletivo agonista dos adrenoceptores α-2 com propriedades simpatic...

  17. A risk-benefit assessment of intra-articular corticosteroids in rheumatic disorders.

    Science.gov (United States)

    Hunter, J A; Blyth, T H

    1999-11-01

    The appeal of intra-articular corticosteroid therapy has increased with the growing emphasis on early disease control in rheumatoid disease. The impact on the patient's pain and stiffness is impressive and prompt. This may encourage patient compliance with longer term therapies given to slow the course of the disease. The release of corticosteroid into the circulation also provides some generalised improvement. This can prove helpful during the management of flares of inflammatory disease. There is less evidence to support the use of intra-articular corticosteroids in other inflammatory arthritides, but experience suggests that the benefits are similar. In osteoarthritis the benefits are less certain, but intra-articular therapy may prove important in patients who cannot undergo salvage operative procedures because of intercurrent illness. The benefits of intra-articular corticosteroids may be enhanced by rest after the injection, or by the additional administration of agents such as radio-colloids, rifampicin (rifampin), or osmic acid. Most controlled trial data have been published on knee injections, but other joints can be useful targets for local therapy. The risks are mainly related to the discomfort of the procedure, localised pain post-injection and flushing, but most feared is septic arthritis which probably occurs in about 1 in 10000 injections. Careful aseptic technique is the best protection. Tissue atrophy at the injection site, abnormal uterine bleeding, hypertension and hyperglycaemia rarely cause problems. Osteonecrosis might be as much a problem with uncontrolled painful arthritis as with a joint rendered less symptomatic by corticosteroid injections. Intra-articular corticosteroids form an important part of the management of inflammatory joint disease and might be considered where an inflammatory element occurs in osteoarthritis. They may be used at any stage in the arthritic process, but should be seen as an adjunct to other forms of symptom

  18. Imágenes en odontología clínica. Úlcera palatina post anestesia.

    Directory of Open Access Journals (Sweden)

    Rodrigo Fernández

    2017-08-01

    Full Text Available Una mujer de 42 años de edad, acude a la consulta odontológica presentando una úlcera palatina de 2 semanas de evolución en relación al diente 2.6. Este diente se encuentra ausente debido a una exodoncia previa del mismo tiempo de evolución. La lesión ulcerada presenta de halo eritematoso, de 2 cm de diámetro, borde indurado y fondo limpio. Adicionalmente, la paciente describe haber recibido radioterapia como tratamiento para un carcinoma de tiroides y uso diario de Eutirox®. Se determinó el diagnóstico clínico de ulceración palatina posterior a anestesia infiltrativa. La lesión a nivel palatino fue controlada y tratada con anestésico local tópico, luego de lo cual cicatrizo por segunda intensión al cabo de 14 días. La aplicación de anestesia local, en raras ocasiones, puede causar ulceración y necrosis en el sitio de la inyección. Esto puede deberse a i los efectos de la isquemia localizada causada por la epinefrina o ii por una técnica anestésica defectuosa (inyección subperiostal o exceso de solución.

  19. Postoperative analgesia in TKA: ropivacaine continuous intraarticular infusion.

    Science.gov (United States)

    Gómez-Cardero, Primitivo; Rodríguez-Merchán, E Carlos

    2010-05-01

    Postoperative pain control is a challenge in patients undergoing TKA due to side effects and technical limitations of current analgesic approaches. Local anesthetic infiltration through continuous infusion pumps has been shown to reduce postoperative pain in previous studies. We assessed the effectiveness of intraarticular ropivacaine infusions in reducing pain and postoperative opioid use after TKA and determined whether such infusions accelerate functional recovery of the patient and reduce length of hospital stay. In a randomized, prospective, double-blind study, two groups were assigned: Group A (n = 25) underwent continuous intraarticular infusion with 300 mL ropivacaine 0.2% at a speed of 5 mL/hour through an elastomeric infusion pump and Group B (n = 25) had an elastomeric pump insertion with 300 mL saline solution at an infusion speed of 5 mL/hour. All patients had the same prosthesis model implanted. Parameters analyzed over the first 3 days, at discharge, and 1 month later included postoperative pain, joint function, opioid use, and length of hospital stay. All patients in Group A showed a decrease in pain intensity measured by a visual analog scale and opioid use in the first 3 days. Mean length of hospital stay was also reduced in Group A (5.72 days) compared to Group B (7.32 days). There were no device-related complications. Use of an infusion pump is effective in treating pain after TKA, reducing postoperative pain and opioid use. It also improves immediate functionality and patient comfort, reducing the mean length of hospital stay, without increasing the risk of complications. Level I, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

  20. Detection of intraarticular bodies of the elbow with saline arthrosonography

    International Nuclear Information System (INIS)

    Miller, John H.; Beggs, Ian

    2001-01-01

    AIM: To assess whether ultrasound with intraarticular injection of saline increases the detection of intraarticular bodies of the elbow. SUBJECTS AND METHODS: Twelve patients (age range 21-42 years, mean 29 years; 8 male, 4 female) referred over a 2-year period with an equivocal history of elbow locking and plain radiographs had a joint injection of at least 12 ml of sterile saline during ultrasound examination. No patient had a joint effusion before injection. Surgical correlation was available in six patients. RESULTS: Ten patients had intraarticular bodies but these were demonstrated only after joint injection in six patients. Arthroscopy performed in six patients confirmed intraarticular bodies in five. Radiographs were falsely positive in one and falsely negative in seven patients. CONCLUSION: Joint injection improves the sonographic evaluation and conspicuity of small and radiographically occult intraarticular loose bodies in the clinically equivocal elbow. The procedure is simple, quick, well tolerated and reproducible. Miller, J. and Beggs, I. (2001)

  1. Dexmedetomidina: papel atual em anestesia e cuidados intensivos

    Directory of Open Access Journals (Sweden)

    Joana Afonso

    2012-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Atualizar e rever a aplicação da dexmedetomidina em anestesia e cuidados intensivos. Este trabalho é uma revisão abrangente dos usos clínicos, farmacologia, farmacocinética, mecanismo de ação e efeitos adversos da dexmedetomidina. CONTEÚDO: O uso efetivo de agentes sedativo-hipnóticos e analgésicos é parte integral do conforto e segurança dos pacientes. A dexmedetomidina é um potente e altamente seletivo agonista dos adrenoceptores α-2 com propriedades simpaticolíticas, sedativas, amnésicas e analgésicas, que tem sido descrito como um adjuvante útil e seguro em várias aplicações clínicas. Proporciona uma "sedação consciente" única, analgésica, sem depressão respiratória. Os usos correntes revistos incluem sedação na unidade de tratamento intensivo - UTI (adulta e pediátrica, departamento de emergência, anestesia regional e geral, neurocirurgia, sedação para procedimentos pediátricos, intubação por fibra ótica em doentes acordados, cirurgia cardíaca e cirurgia bariátrica. CONCLUSÕES: A dexmedetomidina oferece a capacidade única de fornecer sedação e analgesia sem depressão respiratória. É um agente novo com uma grande margem de segurança, excelente capacidade sedativa e moderadas propriedades analgésicas. Embora o seu amplo uso seja, atualmente, em pacientes de unidades de cuidados intensivos cirúrgicos e não cirúrgicos, a dexmedetomidina parece ter futuras aplicações promissoras nas áreas de neuroproteção, cardioproteção e renoproteção. São necessários mais estudos detalhados para definir o seu papel como sedativo em doentes críticos, neurocirúrgicos e pediátricos, como adjuvante da anestesia e como sedativo durante procedimentos

  2. Intra-articular injection of hyaluronic acid for treatment of osteoarthritis knee: comparative study to intra-articular corticosteroids

    Directory of Open Access Journals (Sweden)

    Soad A Elsawy

    2017-01-01

    Conclusion Both HA and corticosteroid groups showed improvement in pain and knee function, but the intra-articular HA was superior to corticosteroid on long-term follow-up. This supports the potential rate of intra-articular HA as an effective long-term therapeutic option for patients with OA of the knee.

  3. Are intraarticular steroids effective for knee osteoarthritis?

    OpenAIRE

    Jorge Faúndez; Petre Cotoras; Sebastián Irarrázaval

    2016-01-01

    Resumen La artrosis de rodilla es una enfermedad crónica, invalidante, de evolución progresiva e irreversible. Los corticoides intraarticulares han sido comúnmente utilizados con el fin de disminuir sus síntomas y retrasar la resolución quirúrgica. Sin embargo, hasta el día de hoy, existe debate sobre su eficacia y seguridad. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, se identificaron 12 revisiones sistemáticas que en conjunto i...

  4. Bupivacaina ou bupivacaina e morfina intra-articular pós reconstrução do LCA Intra-articular bupivacaine or bupivacaine and morphine after ACL reconstruction

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius Danieli

    2012-01-01

    Full Text Available OBJETIVO: A cirurgia de reconstrução do LCA é hoje uma das mais realizadas e o controle da dor pós-operatória faz parte das prioridades do cirurgião. Dentro do arsenal de analgesia temos a aplicação intra-articular de drogas, sendo a mais estudada a bupivacaina associada ou não a morfina. Neste estudo comparamos a aplicação de bupivacaina associada ou não a morfina com grupo controle, após reconstrução do LCA com enxerto de tendões flexores. MÉTODOS: Quarenta e cinco pacientes foram randomizados em três grupos, sendo que no grupo I foi aplicado ao fim da cirurgia 20ml de soro fisiológico intra-articular, no grupo II 20ml de bupivacaina 0,25% e no grupo III bupivacaina 0,25% associado a 1mg de morfina. Os grupos foram avaliados quanto ao grau de dor pela escala analógica visual com 6, 24 e 48 horas de pós-operatório. RESULTADOS: O grupo III teve menos dor em todos os momentos, porém a dor não foi tão intensa em todos os grupos a ponto de necessitar medicações extras além do protocolo estabelecido. CONCLUSÃO: A aplicação intra-articular destas medicações pós-reconstrução do LCA com enxerto dos tendões flexores quando realizada sob anestesia raquideana não traz vantagens suficientes para fazer seu uso regularmente. Nível de Evidência II, Ensaio Clínico Randomizado de Menor Qualidade.OBJECTIVE: Reconstructive surgery of the ACL is one of the most commonly performed surgeries today and the control of postoperative pain is part of the priorities of the surgeon. Within the arsenal of analgesia we have the intra-articular application of drugs, and the most studied one is bupivacaine with or without morphine. This study compared the application of bupivacaine with or without morphine with a control group after ACL reconstruction with flexor tendon graft. METHODS: Forty-five patients were randomized into three groups: in group I, 20 ml of saline were applied intra-articularly at the end of the surgery; in group II

  5. Intra-articular calcaneal fractures. Current concepts.

    Science.gov (United States)

    Stone, M L

    1995-10-01

    Intra-articular fractures of the calcaneus should be treated like any other fractures of major weight-bearing joints. Technology has advanced significantly in the evaluation of such complex pathology. Surgical instrumentation is now available to address any fracture classification. In the past, this had been a problem, as maintenance of the anatomic reduction, rigid internal/dynamic external fixation, and early mobilization may not have been attainable. The two remaining major variables are the mechanism of injury and its force that creates the fracture in combination with a very complex intra-articular anatomical structure. There will always be some morbidity in complex and serious fractures, but at least a more favorable outcome may be attainable with application of the current concepts discussed in this text. Finally, the most crucial factor when dealing with this trauma is the skill of the surgeon, which includes his or her decision-making, preoperative planning, surgical acumen, atraumatic technique, experience, and training and postoperative management of possible complications.

  6. Are intraarticular steroids effective for knee osteoarthritis?

    Directory of Open Access Journals (Sweden)

    Jorge Faúndez

    2016-12-01

    Full Text Available Resumen La artrosis de rodilla es una enfermedad crónica, invalidante, de evolución progresiva e irreversible. Los corticoides intraarticulares han sido comúnmente utilizados con el fin de disminuir sus síntomas y retrasar la resolución quirúrgica. Sin embargo, hasta el día de hoy, existe debate sobre su eficacia y seguridad. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, se identificaron 12 revisiones sistemáticas que en conjunto incluyen 41 estudios que contestan la pregunta de interés, entre los cuales se cuentan 40 estudios aleatorizados. Realizamos un metanálisis y tablas de resumen de los resultados utilizando el método GRADE. Concluimos que los corticoides intraarticulares probablemente llevan a una leve disminución del dolor a corto plazo, hacen poca o ninguna diferencia a mediano plazo y podrían no tener ningún efecto a largo plazo.

  7. Intra-articular osteoid osteoma as a differential diagnosis of diffuse mono-articular joint pain.

    Science.gov (United States)

    Rolvien, Tim; Zustin, Jozef; Mussawy, Haider; Schmidt, Tobias; Pogoda, Pia; Ueblacker, Peter

    2016-11-04

    The aim of this retrospective study was to investigate the frequency of intra-articular osteoid osteoma (iaOO) in a large study cohort and to demonstrate its clinical relevance as an important differential diagnosis of non-specific mono-articular joint pain. We searched the registry for bone tumours of the University Medical Centre Hamburg-Eppendorf for osteoid osteomas in the last 42 years. Herein, we present three selected iaOO which were detected in the three major weight-bearing joints. Computed tomography (CT) or magnetic resonance imaging (MRI) scans were performed for initial diagnosis. Out of a total of 367 osteoid osteomas, 19 (5.2 %) tumours were localized intra-articularly. In all three presented tumours, a history of severe mono-articular pain was reported; however, the mean time to correct diagnosis was delayed to 20.7 months. Clearly, the nidus seen in CT and MRI images in combination with inconsistent salicylate-responsive nocturnal pain led to the diagnosis of iaOO. Rarely, osteoid osteoma can occur in an intra-articular location. In cases of diffuse mono-articular pain, iaOO should be considered both in large and smaller joints to avoid delays in diagnosis and therapy of this benign bone tumour.

  8. Models of presentation of intraarticular masses; Normas de presentacion de las masas intraarticulares

    Energy Technology Data Exchange (ETDEWEB)

    Vega, M. [Hospital Universitario Dr. Peset. Valencia (Spain); Molla, E. [Clinica Quiron. Valencia (Spain); Marti-Bonmati, L.; Galant, J. [Hospital San Juan. Alicante (Spain); Madariaga, B. [Hospital Clinico Zaragoza (Spain)

    2002-07-01

    Intraarticular masses are relatively rare, and their magnetic resonance (MR) features are little known. The purpose of this report was to asses the presentation and MR imaging findings associated with the different histological types encountered in a series of 22 patients. We review the MR imaging findings in 22 intraarticular masses (18 in knee, two in ankle and two in shoulder). The variables studied were: calcifications, edema, morphology, methemoglobin, hemosiderin, homogeneity, margins, bone changes, T1-weighted signal intensity, T2-weightes/STIR signal intensity, clinical presentation and patient age. The statistical relationships were determined by {chi}''2 test and ANOVA (Student-Newman-Keuls). Among the intraarticular masses, there were 14 cases of pigmented villonodular synovitis (SVNP) (63.6%), 3 cases of themangioma (13.6%), 3 cases of synovial sarcoma (13.6%) and 2 cases of chondrosarcoma (9.1%). Statistical significant relationships were observed between histological type and; calcifications (p=0.004), which were irregular in chondrosarcomas and appeared as phleboliths in hemangionas: morphology (p=0.007), which was serpiginous in hemangiomas and oval in focal SVNP; areas of hemosiderin (p=0.002)in SVNP and synovial sarcoma: clinica presentation (p=0.003), with skin changes in cases of hemangioma: and age (p=0.04), hemangioma patients being younger (mean: 21 years) and those with synovial sarcoma being older (mean: 56 years). In cases of intraarticular masses, the presence of calcification, tumor morphology, the presence of hemosiderin, patient age and clinical presentation show statistically significant differences depending on the histological type. (Author) 23 refs.

  9. Bilateral Intra-Articular Radiofrequency Ablation for Cervicogenic Headache

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    Charles A. Odonkor

    2017-01-01

    Full Text Available Introduction. Cervicogenic headache is characterized by unilateral neck or face pain referred from various structures such as the cervical joints and intervertebral disks. A recent study of patients with cervical pain showed significant pain relief after cervical medial branch neurotomy but excluded patients with C1-2 joint pain. It remains unclear whether targeting this joint has potential for symptomatic relief. To address this issue, we present a case report of C1-2 joint ablation with positive outcomes. Case Presentation. A 27-year-old female presented with worsening cervicogenic headache. Her pain was 9/10 by visual analog scale (VAS and described as cramping and aching. Pain was localized suboccipitally with radiation to her jaw and posterior neck, worse on the right. Associated symptoms included clicking of her temporomandibular joint, neck stiffness, bilateral headaches with periorbital pain, numbness, and tingling. History, physical exam, and diagnostic studies indicated localization to the C1-2 joint with 80% decrease in pain after C1-2 diagnostic blocks. She underwent bilateral intra-articular radiofrequency ablation of the C1-C2 joint. Follow-up at 2, 4, 8, and 12 weeks showed improved function and pain relief with peak results at 12 weeks. Conclusion. Clinicians may consider C1-C2 joint ablation as a viable long-term treatment option for cervicogenic headaches.

  10. Intra-articular morphine in horses

    DEFF Research Database (Denmark)

    Lindegaard, Casper

    to a multimodal analgesia protocol. Despite that no research has investigated this issue in horses so far, IA injection of morphine after arthroscopic surgery has become common practice in several veterinary university teaching hospitals in Europe and USA. The aims of this thesis were to investigate the analgesic...... for pharmacological analysis were obtained repeatedly. Pain was evaluated by degree of lameness as well as using a visual analogue scale of pain intensity (VAS) and a composite measure pain scale (CMPS), developed for this purpose. Intra-articular injection of LPS elicited a marked synovitis resulting in lameness...... compared to the same dose administered IV, was demonstrated. In combination with the results of the pharmacologic analysis, this is highly suggestive of a peripherally mediated effect of IA morphine....

  11. Bifurcated intraarticular long head of biceps tendon

    Directory of Open Access Journals (Sweden)

    Vivek Pandey

    2014-01-01

    Full Text Available Though rare, many anomalous origins of long head of the biceps tendon (LHBT have been reported in the literature. Anatomic variations commonly explained are a third humeral head, anomalous insertion, congenital absence and adherence to the rotator cuff. We report a rare case who underwent shoulder arthroscopy with impingement symptoms where in LHBT was found to be bifurcated with a part attached to superior labrum and the other part to the posterior capsule of joint. Furthermore, intraarticular portion of LHBT was adherent to the undersurface of the supraspinatus tendon. Awareness of such an anatomical aberration during the shoulder arthroscopy is of great importance as it can potentially avoid unnecessary confusion and surgery.

  12. Analgesic control after hip arthroscopy: a randomised, double-blinded trial comparing portal with intra-articular infiltration of bupivacaine.

    LENUS (Irish Health Repository)

    Baker, Joseph F

    2011-06-07

    Abstract: The optimum anaesthetic and analgesic management following hip arthroscopy is yet to be determined. There is, in addition, some concern over the use of intraarticular local anaesthetic. We compared the analgesic efficacy of intra-articular infiltration compared with portal infiltration of bupivacaine following hip arthroscopy. Patients were randomised to receive either 10ml of 0.25% bupivacaine either into the joint or around the portal sites following completion of surgery. 73 patients were recruited (40 intra-articular). The portal infiltration group required significantly more rescue analgesia immediately after surgery (2.33mg vs.0.57mg, p=0.036). Visual Analogue Scale pain scores were not significantly different at 1 and 2 hours following surgery, but at 6 hours the portal group had significantly lower VAS scores (p=0.0036). We believe that the initial pain following surgery results from capsular injury and this explains the need for more rescue analgesia in the portal infiltration group. Further work is needed to establish the ideal regimen. A combination of portal and intra-articular infiltration may be the most efficacious.

  13. Padronização da anestesia em suínos para procedimentos cirúrgicos cardiovasculares experimentais

    OpenAIRE

    Geovanini, Glaucylara Reis; Pinna, Fábio R.; Prado, Flávio A. P.; Tamaki, Wagner Tetsuji; Marques, Euclides

    2008-01-01

    JUSTIFICATIVA E OBJETIVO: Embora sejam os cães os animais mais utilizados em Cirurgia Experimental, nota-se crescente utilização de ovinos, bovinos e suínos como modelos para experimentação científica. Assim, faz-se necessário maior aprendizado de seu tratamento e padronizações básicas para os procedimentos cirúrgicos mais complexos em suínos. O objetivo foi avaliar a sedação e analgesia, obtidas pela injeção intramuscular de midazolam e cetamina e anestesia local com lidocaína a 2% sem vasoc...

  14. Book review. Anestesia e analgesia locoregionale del cane e del gatto. Francesco Staffieri

    Directory of Open Access Journals (Sweden)

    Manuel Graziani

    2014-03-01

    Full Text Available Il volume di anestesia e analgesia locoregionale del cane e del gatto è pensato per essere un testo "da sala operatoria" – come afferma l'autore – perché consente un rapido, ma allo stesso tempo dettagliato, consulto per il libero professionista che si trova a gestire un'anestesia. Si tratta di un piccolo libro, tascabile, che può essere considerato un punto di partenza per gli studenti e per tutti quei medici veterinari che intendono avvicinarsi in maniera specialistica all'arte dell'anestesiologia veterinaria. L'anestesia locoregionale costituisce, infatti, uno strumento insostituibile per la gestione del dolore perioperatorio in medicina veterinaria. Nel volume si forniscono le nozioni di base per praticare i principali blocchi nervosi centrali e periferici. Per ogni blocco sono riportate le tecniche alla cieca (mediante l'ausilio dei punti di repere anatomici e quelle con l'impiego dello stimolatore nervoso periferico. Il volume, corredato da immagini foto e grafici, per un totale di 65 figure, si apre con i capitoli relativi ai farmaci, agli strumenti e alle complicanze dell'anestesia locoregionale. Prosegue con i blocchi nervosi centrali (anestesia epidurale e spinale e si conclude con i blocchi periferici (testa, arto anteriore, torace, arto posteriore. L'autore, Francesco Staffieri, è un medico veterinario che svolge il dottorato di ricerca nel Dipartimento delle Emergenze e dei Trapianti di Organi, Sezioni di Cliniche Veterinarie e Produzioni Animali dell'Università degli Studi Aldo Moro di Bari.

  15. Knee chondrolysis by infusion of bupivacaine with epinephrine through an intra-articular pain pump catheter after arthroscopic ACL reconstruction.

    Science.gov (United States)

    Buchko, Jordan Z; Gurney-Dunlop, Tanner; Shin, Jason J

    2015-02-01

    compared with those exposed to 0.25% (P = .03). Patients with chondrolysis had severe pain and limitations in daily activity. The development of knee chondrolysis was associated with the intra-articular infusion of bupivacaine with epinephrine postoperatively. Furthermore, the presented evidence suggests that this occurs in a dose-dependent manner. The risk of knee chondrolysis might be reduced by avoidance of intra-articular infusion of bupivacaine with epinephrine. We recommend against continuous intra-articular infusion of local anesthetic postoperatively. © 2014 The Author(s).

  16. Comparison of intra-articular tenoxicam and oral tenoxicam for pain and physical functioning in osteoarthritis of the knee.

    Science.gov (United States)

    Unlu, Zeliha; Ay, Kamuran; Tuzun, Cigdem

    2006-02-01

    This study was designed to compare efficacy of local administration of a nonsteroidal anti-inflammatory drug with systemic administration in patients with osteoarthritis (OA) of the knee. For this purpose, intra-articular tenoxicam and oral tenoxicam therapies were applied and the improvement in control of pain and physical functioning were evaluated. A total of 69 patients with OA of the knee were randomized into three groups. Patients in the first group (41 knees of 23 patients) were treated for 1-3 weeks with once weekly intra-articular injection of tenoxicam 20 mg. Patients in the second group (45 knees of 26 patients) received 20 mg/day tenoxicam orally for 3 weeks and only physical exercises were applied to the third group (32 knees of 20 patients). Physical examination of the knee joint, Western Ontario and McMaster Universities Index and the Lequesne Algofunctional Index were used as outcome measurements at baseline, and the 1st, 3rd and 6th months. More significant improvement in pain and disability parameters was observed in groups 1 and 2 than group 3 compared with baseline measures. Among the patients' responses a few of the differences were statistically significant, more in favour of tenoxicam, and tenoxicam seemed to be superior to exercise alone especially at the final evaluation. There was no significant difference between the oral and intra-articular tenoxicam treatment regimens. The results of this study showed that treatment of OA of the knee with intra-articular tenoxicam is as effective as that with oral tenoxicam. It can be thought that intra-articular administration can be preferred to oral therapy due to minimal possibility of systemic side effects.

  17. Efficacy and safety of combining intra-articular methylprednisolone and anti-TNF agent to achieve prolonged remission in patients with recurrent inflammatory monoarthritis.

    LENUS (Irish Health Repository)

    Haroon, Muhammad

    2012-02-01

    OBJECTIVE: To control local inflammation, the role of intra-articular corticosteroid is well established; similarly, with time there are more reports on the experience of intra-articular anti-TNF agent for localized joint inflammation. The aim of this study was to assess the safety, local tolerability and clinical response after combining intra-articular administration of corticosteroids and anti-TNF agents for recurrent inflammatory monoarthritis. METHODS: Patients with recurrent monoarthritis of the knee were recruited from our inflammatory arthritis clinics. These patients required intra-articular corticosteroids every 8-12 weeks, with good short-term results. Five such consecutive patients were invited to partake in this study. Patients were maintained on their baseline immunosuppressive therapy. After aspiration of knee joint, the involved joint was injected with 80mg of methylprednisolone mixed with 5ml of lignocaine 1%; this was followed by the injection of an anti-TNF agent. RESULTS: In majority of our patients (three out of five), combining anti-TNF agent and methylprednisolone led to prolonged anti-inflammatory response, and these patients remain in remission to date (mean follow-up of 12 months). These responders were noted to be naive to anti-TNF therapy. Conversely, the remaining two patients were found to be on baseline systemic anti-TNF therapy, and both of them failed to respond either partly or completely. CONCLUSION: Combining intra-articular corticosteroid and anti-TNF agent has proved to be safe in our cohort of patients. We conclude that in particular subset of patients who suffer from recurrent inflammatory monoarthritis or oligoarthritis, combination therapy of intra-articular corticosteroids and anti-TNF agents appears attractive and promising.

  18. Local anaesthetics and chondrotoxicty: What is the evidence?

    LENUS (Irish Health Repository)

    Baker, Joseph F

    2012-11-01

    Recent reports have suggested that local anaesthetic agents have a toxic effect on articular chondrocytes. This is despite the widespread intra-articular use of local anaesthetic agents following arthroscopic procedures for a number of years.

  19. Anestesia epidural na cirurgia descompressiva lombossacral de cães

    Directory of Open Access Journals (Sweden)

    E.A. Tudury

    2014-06-01

    Full Text Available Objetivou-se avaliar viabilidade, eficácia, vantagens e desvantagens da anestesia epidural lombossacral, junto à anestesia geral inalatória, em cirurgias de descompressão da cauda equina, tendo em vista que essas cirurgias são procedimentos longos e dolorosos. Para isso, foram utilizados 11 cães adultos com sinais clínicos de síndrome da cauda equina, que foram submetidos à anestesia geral inalatória e deixados no estágio anestésico mais superficial. Depois, realizou-se a anestesia epidural em seis dos 11 pacientes, por punção espinhal em L7-S1, com bupivacaína a 0,5%. Os parâmetros fisiológicos (cardíacos, vasculares, respiratórios, temperatura corporal e glicemia foram aferidos antes da medicação pré-anestésica, 10 minutos após esta, 30 minutos depois da epidural, depois da laminectomia, assim como após 60 minutos e 90 minutos da epidural, tanto no grupo com epidural como naquele sem esta (controle. Os animais que possuíam bloqueio epidural apresentaram redução significativa no consumo de anestésico inalatório e no tempo de extubação, não apresentando déficits neurológicos causados pela anestesia epidural, quando comparados com o grupo-controle. Conclui-se que a técnica de anestesia epidural é eficiente e vantajosa na realização de cirurgias descompressivas lombossacrais, pois proporciona menor risco anestésico para o animal.

  20. Padronização da anestesia em suínos para procedimentos cirúrgicos cardiovasculares experimentais

    Directory of Open Access Journals (Sweden)

    Glaucylara Reis Geovanini

    2008-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVO: Embora sejam os cães os animais mais utilizados em Cirurgia Experimental, nota-se crescente utilização de ovinos, bovinos e suínos como modelos para experimentação científica. Assim, faz-se necessário maior aprendizado de seu tratamento e padronizações básicas para os procedimentos cirúrgicos mais complexos em suínos. O objetivo foi avaliar a sedação e analgesia, obtidas pela injeção intramuscular de midazolam e cetamina e anestesia local com lidocaína a 2% sem vasoconstritor, na realização de traqueostomia, dissecção de artéria e veia femorais. MÉTODO: A freqüência cardíaca e o reflexo córneo-palpebral foram avaliados logo no início da sedação, durante os procedimentos cirúrgicos descritos e após seu término. Foram utilizados oito suínos fornecidos por fazendas locais sem tratamento prévio da raça Large White, com peso de 35 a 42 quilos que receberam injeção intramuscular de 22 mg.kg-1 de cetamina e 0,3 mg.kg-1 de midazolam. RESULTADOS: A abordagem anestésica nesses animais, de difíceis intubação e acesso aos vasos profundos, provou ser segura para sedação e analgesia através do método utilizado: acesso intramuscular. CONCLUSÃO: Obteve-se adequado plano de anestesia para o procedimento proposto.

  1. Prótesis fija con anestesia acupuntural Fixed prosthesis with acupuncture anesthesia

    Directory of Open Access Journals (Sweden)

    Marcia Hortensia Corona Carpio

    2006-09-01

    Full Text Available Se presenta un caso de una paciente femenina de 72 años de edad con antecedentes alérgicos a la anestesia dental y preocupación de rehabilitar su estética con prótesis fija. Se decidió aplicar anestesia acupuntural en la preparación de los pilares para recibir el puente fijo. Se exponen las técnicas y los resultados obtenidos. No se manifestaron reacciones adversas. La paciente evolucionó satisfactoriamente con el tratamiento alternativo realizado.

  2. Prótesis fija con anestesia acupuntural Fixed prosthesis with acupuncture anesthesia

    OpenAIRE

    Marcia Hortensia Corona Carpio; Niurka Odalmis Lao Salas; Silvana Oliveros Noriega; Yanisette Mónica Calleja Martínez; Walkyria González Rodríguez

    2006-01-01

    Se presenta un caso de una paciente femenina de 72 años de edad con antecedentes alérgicos a la anestesia dental y preocupación de rehabilitar su estética con prótesis fija. Se decidió aplicar anestesia acupuntural en la preparación de los pilares para recibir el puente fijo. Se exponen las técnicas y los resultados obtenidos. No se manifestaron reacciones adversas. La paciente evolucionó satisfactoriamente con el tratamiento alternativo realizado.

  3. Espondilodiscitis secundaria a anestesia peridural Spondilodiscitis secondary to peridural anesthesia

    Directory of Open Access Journals (Sweden)

    Yvei González Orlandi

    2010-12-01

    Full Text Available Se presenta el caso de un paciente con espondilodiscitis secundaria al uso de anestesia peridural lumbar para la resección transuretral de una hiperplasia fibroadenomatosa de la próstata. El cuadro clínico estuvo determinado por lumbalgia aguda con incremento progresivo que llevó al confinamiento en cama del paciente. En el examen físico del sistema osteomioarticular predominó la contractura paravertebral lumbar, así como en la palpación de esta región. En el examen neurológico no se encontraron alteraciones. La tomografía axial computarizada multicorte, así como la gammagrafía ósea de columna lumbar, confirmaron el diagnóstico. Se indicó tratamiento médico basado en los síntomas, antibioticoterapia combinada y ortesis externa. La recuperación total del paciente ocurrió a los 6 meses del inicio de la enfermedad.This is the case of a patient presenting with spondilodiscitis secondary to use of lumbar peridural anesthesia for transurethral resection of a prostatic fibroadenoma hyperplasia The clinical picture was determined by a acute lumbar pain with a progressive increase leading to put to bed the patient. In physical examination of osteomyoarticular system there was predominance of lumbar paravertebral contracture, as well as in palpation of this region. In neurological examination there weren't alterations. The multi-scan computed axial tomography and the spine column bone scintigraphy confirmed the diagnosis. Medical treatment was prescribed based on symptoms, combined antibiotic drug therapy and external orthesis. The total recovery of patient occurred at 6 months from the onset of disease.

  4. Sustained intra-articular release of celecoxib from in situ forming gels made of acetyl-capped PCLA-PEG-PCLA triblock copolymers in horses

    NARCIS (Netherlands)

    Petit, Audrey; Redout, Everaldo M; van de Lest, Chris H; de Grauw, Janny C; Müller, Benno; Meyboom, Ronald; van Midwoud, Paul; Vermonden, Tina; Hennink, Wim E; van Weeren, René

    In this study, the intra-articular tolerability and suitability for local and sustained release of an in situ forming gel composed of an acetyl-capped poly(ε-caprolactone-co-lactide)-b-poly(ethylene glycol)-b-poly(ε-caprolactone-co-lactide) (PCLA-PEG-PCLA) copolymer loaded with celecoxib was

  5. Intra-articular hip injection: does pain relief correlate with radiographic severity of osteoarthritis?

    International Nuclear Information System (INIS)

    Deshmukh, Ajit J.; Rodriguez, Jose A.; Panagopoulos, Georgia; Alizadeh, Ahmadreza; Klein, Devon A.

    2011-01-01

    Intra-articular injection is being used widely for both diagnostic and therapeutic purposes in the hip. However, its efficacy is not always predictable in patients with hip osteoarthritis (OA). The purpose of this study was to determine whether the degree of radiographic severity of OA was predictive of the response to intra-articular injection of local anesthetic with corticosteroid and to determine the relationship between immediate pain relief resulting from the anesthetic and delayed pain relief resulting from corticosteroid administration. This retrospective study included 217 patients (220 injections) with diagnosis of hip OA who underwent a fluoroscopically guided therapeutic hip injection of local anesthetic and corticosteroid. Hip radiographs were scored using the Kellgren-Lawrence scale. Immediate and delayed pain relief was documented using a visual analog scale. Logistic regression analysis was performed to investigate whether age, gender or radiographic severity of OA were independent predictors of pain relief. Degree of agreement between immediate and delayed response was assessed with the kappa coefficient. Immediate pain relief was reported in 68.2% of hips and delayed relief in 71.4% of hips. A high level of agreement was observed between immediate and delayed pain relief (kappa = 0.80, p < 0.001). 94% of patients reporting immediate relief also reported relief 2 weeks later. Univariate and multivariate analysis revealed that neither gender nor age was related to immediate or delayed pain relief. Only severity of OA (based on radiographic analysis) was observed to be predictive of pain relief. Pain relief following intra-articular hip injection correlated with radiographic severity of OA. This intervention may be of therapeutic and prognostic value in patients awaiting hip arthroplasty. (orig.)

  6. Postarthroscopy analgesia using intraarticular levobupivacaine and intravenous dexketoprofen trometamol.

    Science.gov (United States)

    Sahin, Sevtap Hekimoglu; Memiş, Dilek; Celik, Erkan; Sut, Necdet

    2015-12-01

    The aim of this prospective study was to determine the efficacy of intraarticular levobupivacaine with and without intravenous dexketoprofen trometamol for postarthroscopy analgesia. Sixty patients who underwent arthroscopic knee surgery were randomly assigned to three treatment groups. When the surgical procedure was completed, patients received the following treatments: group I (n = 20) patients received 20 mL intraarticular normal saline and 2 mL intravenous dexketoprofen trometamol (50 mg); group II (n = 20) patients received 20 mL intraarticular 0.5 % levobupivacaine (100 mg) and 2 mL intravenous normal saline; and group III (n = 20) patients received 20 mL intraarticular 0.5 % levobupivacaine (100 mg) and 2 mL intravenous dexketoprofen trometamol (50 mg). The visual analogue scale (VAS) was used, and the total analgesic consumption was assessed at 1, 2, 4, 6, 12, and 24 h post-operatively. The VAS scores at 1, 2, 4, 6, 12, and 24 h post-operatively were significantly increased in group I and group II compared with group III (p dexketoprofen trometamol administration provided better pain relief and less analgesic requirement after arthroscopic knee surgery during the first 24 h than that induced by dexketoprofen alone or levobupivacaine intraarticular alone. II.

  7. Intraarticular osteoblastoma with subluxation of the hip joint

    Science.gov (United States)

    Okada, Kyoji; Nagasawa, Hiroyuki; Chida, Schuichi; Nanjo, Hiroshi

    2013-01-01

    Patient: Male, 5 Final Diagnosis: Osteoblastoma Symptoms: — Medication: — Clinical Procedure: — Specialty: Oncology Objective: Rare disease Background: Osteoblastomas are relatively uncommon bone tumors that account for <1% of all bone tumors. They usually occur in the medullary region of the bone. As such, intraarticular osteoblastomas are quite rare. Case Report: In this report, we present the case of a 5-year-old boy who presented with vague pain and subluxation of the hip joint due to an intraarticular osteoblastoma. Radiological examinations showed an irregular calcified mass lesion in the hip joint. The final diagnosis of osteoblastoma was made by histological examination. The patient’s symptoms completely subsided following surgical removal of the tumor. Conclusions: Osteoblastomas can occur in the intraarticular region. Although quite rare, osteoblastoma should be considered among the differential diagnoses for patients with pain and subluxation of the hip joint. PMID:23901353

  8. Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial

    DEFF Research Database (Denmark)

    Toftdahl, Karen; Nikolajsen, Lone; Haraldsted, Viggo

    2007-01-01

    BACKGROUND: Postoperative pain after total knee arthroplasty (TKA) can be difficult to manage and may delay recovery. Recent studies have suggested that periarticular infiltration with local anesthetics may improve outcome. METHODS: 80 patients undergoing TKA under spinal anesthesia were randomized...... to receive continuous femoral nerve block (group F) or peri- and intraarticular infiltration and injection (group I). Group I received a solution of 300 mg ropivacaine, 30 mg ketorolac, and 0.5 mg epinephrine by infiltration of the knee at the end of surgery, and 2 postoperative injections....... No differences between groups were seen regarding side effects or length of stay. INTERPRETATION: Peri- and intraarticular application of analgesics by infiltration and bolus injections can improve early analgesia and mobilization for patients undergoing TKA. Further studies of optimal drugs, dosage...

  9. Intra-Articular Osteotomy for Distal Humerus Malunion

    Directory of Open Access Journals (Sweden)

    René K. Marti

    2009-01-01

    Full Text Available Intra-articular osteotomy is considered in the rare case of malunion after a fracture of the distal humerus to restore humeral alignment and gain a functional arc of elbow motion. Traumatic and iatrogenic disruption of the limited blood flow to the distal end of the humerus resulting in avascular necrosis of capitellum or trochlea is a major pitfall of the this technically challenging procedure. Two cases are presented which illustrate the potential problems of intra-articular osteotomy for malunion of the distal humerus.

  10. Vitrectomía y facovitrectomía con anestesia tópica/intracameral

    Directory of Open Access Journals (Sweden)

    Jesús Oscar Moya Romero

    2015-01-01

    Conclusiones: El uso de anestesia tópica/intracameral en vitrectomía pars plana y facovitrectomía para casos seleccionados es seguro y efectivo como alternativa al bloqueo retrobulbar y peribulbar, evitando complicaciones relativas al bloqueo, con una incidencia de complicaciones similar a lo reportado, y adecuada tolerancia, para el paciente.

  11. Anestesia en el tronco arterioso común

    Directory of Open Access Journals (Sweden)

    Lincoln de la Parte Pérez

    2003-04-01

    Full Text Available El tronco arterioso es una anomalía congénita del corazón poco frecuente, que se asocia con una alta mortalidad. El 50 % de los pacientes fallece antes de los 3 meses de edad y el 80 % antes del año. La causa más frecuente de muerte es el fallo cardíaco agudo. Presentamos una experiencia en 2 lactantes operados en el Cardiocentro del Hospital Pediátrico Universitario "William Soler", durante el año 2001: una niña de 7 meses de edad, desnutrida, con un tronco común tipo II, hipertensión pulmonar y síndrome de DiGeorge, el segundo paciente era un lactante de 3 meses de edad, con un tronco común tipo I. Se utilizó fentanyl en la inducción y el mantenimiento de la anestesia. La temperatura recta se bajó a 25 °C y los tiempos de circulación extracorpórea fueron de 100 y 121 min y el de pinzamiento aórtico de 30 y 31 min. Se utilizó apoyo farmacológico con dobutrex en dosis bajas. Se emplearon fentanyl, vasodilatadores en infusión continua e hiperventilación, como medidas para evitar la crisis de hipertensión pulmonar. Los enfermos evolucionaron satisfactoriamente durante todo el transoperatorio.The truncus arteriosus is a rare congenital abnormality that is associated with high mortality. 50 % of the patients died before being 3 months old and 80 % before the first year. The most frequent cause of death is acute heart failure. The cases of 3 infants operated on at the Heart Center of William Soler Pediatric Teaching Hospital during 2001 are presented: a seven-old month malnourished girl with a type II common truncus, pulmonary hypertension and DiGiorgio's syndrome, and a 3-month-old female infant with type I common truncus. Fentanyl was used in the induction and maintenance of anesthesia. The straight temperature was lowered to 25 °C, whereas the times of extracorporeal circulation were 100 and 121 min and those of the aortic clamping were 30 and 31 min. Low doses of dobutrex were administered as pharmacological support

  12. Anestesia en la coartación de la aorta

    Directory of Open Access Journals (Sweden)

    Lincoln de la Parte Pérez

    2001-12-01

    Full Text Available Se presenta un estudio retrospectivo de 200 pacientes operados de coartación de la aorta, en el Cardiocentro del Hospital Pediátrico Universitario "William Soler", en el período de 1990 a 1995. La ketamina fue el agente más utilizado en la premedicación anestésica de nuestros pacientes (190 pacientes, 95 %. En 150 pacientes se utilizó asociada con la atropina y en 40 se le adicionó además midazolam. En los 10 enfermos restantes se empleó sólo atropina. El fentanyl fue el agente más utilizado en la inducción de la anestesia (123 pacientes, 61,5 % y en el mantenimiento (186 enfermos, 92 % y aportó gran estabilidad hemodinámica. Se empleó vasodilatador en la mayoría de los pacientes (176 pacientes, 88 %, para el control de la presión arterial y dentro de éstos, los más utilizados fueron la nitroglicerina mezclada con regitina en 135 pacientes (67,5 %. Las complicaciones más frecuentes fueron la hipertensión arterial (76 pacientes, 38 % la acidosis metabólica (24 pacientes, 12 % y las arritmias cardíacas (14 pacientes, 7 %.A retrospective study of 200 patients operated on of aortic coarctation at the Cardiology Center of "William Soler" Pediatric Teaching Hospital from 1990 to 1995 was conducted. Ketamine was the most used agent in the anesthetic premedication of our patients (190 patients, 95 %. It was associated with atropine in 150 patients and midazolan was also added in 40 patients. In the other 10 patients atropine was only used. Fentanyl was the most administered agent in the induction of anesthesia (123 patients, 61.5 % and in the maintenance (186 patients, 92 %. It provided a great hemodynamic stability. Vasodilators were used in most of the patients (176 patients, 88 % to control arterial pressure. The most used were nitroglycerin mixed with regitine (135 patients, 67.5 %. The most frequent complications were arterial hypertension (76 patients, 38 %, metabolic acidosis (24 patients, 12 %, and cardiac arrhytmias (14

  13. A anestesia peridural torácica realizada com segurança no paciente anestesiado: estudo de uma série de casos

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Nunes de Bessa

    2008-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O surgimento de casos de paraplegia seguindo a inserção de cateter peridural em pacientes anestesiados levou a questionamento por parte de alguns autores, mesmo que não se confirme que a lesão tenha ocorrido porque o paciente estava anestesiado. Por esse motivo, idealizamos este estudo, que teve como objetivo avaliar a freqüência de complicações neurológicas e de surgimento de seqüelas após anestesia peridural torácica realizada com os pacientes sob anestesia geral. MÉTODO: Participaram do estudo pacientes submetidos à intervenção cirúrgica torácica no período de 16/02/2004 a 30/05/2006. Após monitoração dos sinais vitais e realização da anestesia geral, os pacientes foram colocados em decúbito lateral e realizada anestesia peridural torácica simples ou contínua. Numa ficha especial foram registradas as intercorrências, complicações e dificuldades na realização da técnica. No pós-operatório os pacientes foram acompanhados em busca de sinais e sintomas de disfunção neurológica. RESULTADOS: Foram avaliados 113 pacientes e em 108 foi inserido cateter peridural torácico. Em 45 pacientes a punção foi considerada traumática, ou seja, sangramento no local da punção e punções múltiplas. Em dois pacientes houve perfuração acidental de dura-máter. No pós-operatório imediato um paciente relatou sensação de formigamento em membros inferiores, outro paciente apresentou dormência em membro superior, desaparecendo com a retirada e tração do cateter. A punção foi única nos dois casos. Nenhum outro paciente apresentou sinais ou sintomas de alterações neurológicas. CONCLUSÕES: Nos casos estudados não houve complicação neurológica. Quando executado com bom senso e cuidados específicos o bloqueio peridural torácico pode ser realizado com segurança no paciente anestesiado.

  14. Subtalar versus triple arthrodesis after intra-articular calcaneal fractures

    NARCIS (Netherlands)

    T. Schepers (Tim); B.C.T. Kieboom (Brenda); J.H.J.M. Bessems (Gert); L.M.M. Vogels (Lucas); E.M.M. van Lieshout (Esther); P. Patka (Peter)

    2010-01-01

    textabstractDepending upon initial treatment, between 2 and 30% of patients with a displaced intra-articular calcaneal fracture require a secondary arthrodesis. The aim of this study was to investigate the effect of subtalar versus triple arthrodesis on functional outcome. A total of 33 patients

  15. Subtalar versus triple arthrodesis after intra-articular calcaneal fractures

    NARCIS (Netherlands)

    Schepers, Tim; Kieboom, Brenda C. T.; Bessems, Gert H. J. M.; Vogels, Lucas M. M.; van Lieshout, Esther M. M.; Patka, Peter

    2010-01-01

    Depending upon initial treatment, between 2 and 30% of patients with a displaced intra-articular calcaneal fracture require a secondary arthrodesis. The aim of this study was to investigate the effect of subtalar versus triple arthrodesis on functional outcome. A total of 33 patients with 37

  16. Anestesia e o usuário de Ecstasy Anestesia y el usuario de Ecstasy Anesthesia and the Ecstasy user

    Directory of Open Access Journals (Sweden)

    Eduardo Toshiyuki Moro

    2006-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Nos últimos anos o número de novos usuários de agentes ilícitos tem aumentado de forma significativa em todo o mundo. A maconha e a cocaína, além do álcool e do tabaco, têm sido os agentes citados com freqüência, porém houve um aumento significativo de usuários de outros agentes psicoestimulantes ou alucinógenos, como o Ecstasy, o GHB, o LSD e a metanfetamina, empregados com o objetivo de intensificar as experiências sociais. O objetivo do presente artigo foi discutir a apresentação clínica, os efeitos deletérios e as potenciais interações com o ato anestésico no paciente cirúrgico usuário desses agentes ilícitos. CONTEÚDO: O artigo discute os mecanismos de ação, a apresentação clínica, os efeitos deletérios e as possíveis repercussões observadas durante a anestesia no usuário de MDMA (3,4-metilenodioximetanfetamina, também conhecido como Ecstasy. CONCLUSÕES: A apresentação clínica e os efeitos deletérios provocados pelo 3,4-metilenodioximetanfetamina (Ecstasy, assim como potenciais interações com o ato anestésico devem ser do conhecimento do anestesiologista, pois em muitas situações esses usuários serão submetidos a intervenções cirúrgicas de emergência, ou mesmo eletivas.JUSTIFICATIVA Y OBJETIVOS: En los últimos años el número de nuevos usuarios de drogas ilícitas ha aumentado de forma significativa en todo el mundo. La marihuana y la cocaína, además del alcohol y del tabaco, han sido las drogas citadas frecuentemente, sin embargo, hubo un aumento significativo de usuarios de otros agentes psicoestimulantes o alucinógenos, como el Ecstasy, el GHB, el LSD y la metanfetamina, empleados con el objetivo de intensificar las experiencias sociales. El objetivo del presente artículo fue el de traer a colación la presentación clínica, los efectos destructivos y las potenciales interacciones con el acto anestésico en el paciente quirúrgico usuario de esas drogas

  17. Anestesia para obesidade mórbida Anestesia para obesidad mórbida Anesthesia for morbid obesity

    Directory of Open Access Journals (Sweden)

    Michelle Nacur Lorentz

    2007-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A obesidade mórbida é uma doença muito freqüente em nosso meio, enquanto nos EUA já assumiu caráter epidêmico. O paciente obeso apresenta uma série de alterações fisiopatológicas, além de importantes comorbidades, o que exige do anestesiologista pleno conhecimento da fisiopatologia da doença. O procedimento cirúrgico de redução gástrica tem sido cada vez mais realizado e o período perioperatório apresenta características únicas com alterações cardiovascular e pulmonar que o tornam um verdadeiro desafio para os profissionais envolvidos. O hospital também deve estar preparado para receber esses pacientes, com equipamentos adequados, equipe multidisciplinar e cuidados pós-operatórios. O objetivo deste estudo foi demonstrar que o paciente obeso mórbido não é apenas um paciente com excesso de peso, e, portanto, procurou-se nortear as principais condutas a serem observadas. CONTEÚDO: São apresentadas neste artigo as principais alterações fisiopatológicas do obeso mórbido, bem como dados de epidemiologia e doenças correlacionadas. É realizada uma revisão das doses dos medicamentos usados na anestesia, bem como a melhor abordagem pré-, intra- e pós-operatória pelo anestesiologista. CONCLUSÕES: A abordagem do paciente com obesidade mórbida exige um planejamento minucioso que se inicia na seleção dos pacientes, tem continuidade com pré-operatório detalhado e intra-operatório individualizado, e se estende até o pós-operatório, quando a incidência de complicações pulmonar, cardiovascular e infecciosa é maior que na população não-obesa. Para que os resultados sejam favoráveis é extremamente importante o envolvimento de uma equipe multiprofissional que inclui Clínica Geral, Anestesiologia, Cirurgia Geral, Enfermagem, Psicologia, Fisioterapia, Nutrologia e Terapia Intensiva.JUSTIFICATIVA Y OBJETIVOS: La obesidad mórbida es una enfermedad muy frecuente en nuestro medio

  18. Stem cells and other innovative intra-articular therapies for osteoarthritis: what does the future hold?

    Directory of Open Access Journals (Sweden)

    Singh Jasvinder A

    2012-05-01

    Full Text Available Abstract Osteoarthritis (OA, the most common type of arthritis in the world, is associated with suffering due to pain, productivity loss, decreased mobility and quality of life. Systemic therapies available for OA are mostly symptom modifying and have potential gastrointestinal, renal, hepatic, and cardiac side effects. BMC Musculoskeletal Disorders recently published a study showing evidence of reparative effects demonstrated by homing of intra-articularly injected autologous bone marrow stem cells in damaged cartilage in an animal model of OA, along with clinical and radiographic benefit. This finding adds to the growing literature showing the potential benefit of intra-articular (IA bone marrow stem cells. Other emerging potential IA therapies include IL-1 receptor antagonists, conditioned autologous serum, botulinum toxin, and bone morphogenetic protein-7. For each of these therapies, trial data in humans have been published, but more studies are needed to establish that they are safe and effective. Several additional promising new OA treatments are on the horizon, but challenges remain to finding safe and effective local and systemic therapies for OA. Please see related article: http://www.biomedcentral.com/1471-2474/12/259

  19. Anestesia no paciente usuário de cocaína Anestesia en el paciente usuario de cocaína Anesthesia in cocaine users

    Directory of Open Access Journals (Sweden)

    Ana Luft

    2007-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A cocaína é a droga ilícita mais freqüentemente associada a óbitos, e suas implicações perioperatórias nos pacientes agudamente intoxicados ou com história de uso crônico precisam ser bem conhecidas pelos anestesiologistas. O conhecimento da neurofisiologia, da farmacologia e das conseqüências fisiopatológicas decorrentes do uso da cocaína poderá facilitar o cuidado desses pacientes. O objetivo deste trabalho foi revisar as informações sobre a cocaína e suas interações com a anestesia. CONTEÚDO: O artigo discute a farmacologia da cocaína, as conseqüências fisiopatológicas decorrentes do seu uso e as interações com a anestesia. CONCLUSÕES: A compreensão e o reconhecimento precoce das complicações associadas ao uso de cocaína são essenciais para o manuseio adequado de pacientes usuários desta droga. O anestesiologista deve estar preparado, pois tanto as anestesias regionais quanto a geral apresentam riscos significativos nesses pacientes.JUSTIFICATIVA Y OBJETIVOS: La cocaína es la droga ilícita más frecuentemente asociada a decesos, y sus implicaciones perioperatorias en los pacientes agudamente intoxicados o con historial de uso crónico necesitan ser muy bien conocidas por los anestesiólogos. El conocimiento de la neurofisiología, de la farmacología y de las consecuencias fisiopatológicas provenientes del uso de la cocaína podrá facilitar el cuidado de esos pacientes. El objetivo de este trabajo fue revisar las informaciones sobre la cocaína y sus interacciones con la anestesia. CONTENIDO: El artículo discute la farmacología de la cocaína, las consecuencias fisiopatológicas provenientes de su uso y las interacciones con la anestesia. CONCLUSIONES: La comprensión y el reconocimiento precoz de las complicaciones asociadas al uso de la cocaína son esenciales para el manejo adecuado de pacientes usuarios de esa droga. El anestesiólogo debe estar preparado, pues tanto las

  20. Síndrome de Turner e anestesia Síndrome de turner y anestesia Turner syndrome and anesthesia

    Directory of Open Access Journals (Sweden)

    Marcius Vinícius M. Maranhão

    2008-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A síndrome de Turner é uma anormalidade genética freqüente e complexa, que afeta mulheres e está associada a uma grande variedade de alterações anatômicas e fisiológicas, em especial relacionadas com as vias aéreas e o sistema cardiovascular. Foi objetivo deste artigo fazer uma revisão das alterações anatomofisiológicas da síndrome de Turner de maior interesse para o anestesiologista, discutir o manuseio perioperatório e fazer uma revisão da literatura a respeito da conduta anestésica nesses pacientes. CONTEÚDO: A síndrome de Turner é uma doença genética caracterizada por anormalidade no número ou morfologia do cromossomo sexual. Com mais freqüência o cromossomo sexual é ausente, resultando em cariótipo 45,X e um fenótipo de disgenesia gonadal. As principais alterações anatomofisiológicas de interesse para o anestesiologista incluem pescoço curto e hipoplasias maxilar e mandibular, o que pode provocar uma via aérea difícil. O menor comprimento da traquéia, bem como sua bifurcação mais superior, pode facilitar a intubação endobrônquica e extubação traqueal acidental quando houver tração da cânula traqueal. Cardiopatias, doenças endócrinas e gastrintestinais, alterações hepáticas e renais, comprometimento osteoarticular, bem como alterações oftálmicas e auditivas, são freqüentes, devendo ser detectados durante a avaliação pré-anestésica. As técnicas de anestesia geral ou regional parecem ser seguras nesse tipo de paciente. CONCLUSÕES: A síndrome de Turner é uma anormalidade genética que apresenta importantes alterações anatomofisiológicas de interesse para o anestesiologista. O conhecimento dessas alterações permite manuseio anestésico seguro com baixa morbimortalidade perioperatória.JUSTIFICATIVA Y OBJETIVOS: El síndrome de Turner es una anormalidad genética frecuente y compleja que afecta a las mujeres y que está asociada a una gran variedad de

  1. Aspectos históricos de la anestesia espinal en Cuba (Primera parte)

    OpenAIRE

    Alexis González Páez; Blas Hernández Suárez

    2003-01-01

    En la historia de la anestesia espinal en Cuba su "rastro" se remonta al día 6 de diciembre de 1900, apenas dos años después de August Bier, en las manos del doctor Enrique Nuñez. Pero no es hasta 1901 que publica su artículo en El Progreso Médico. Después de estas primeras prácticas la anestesia espinal fue casi abandonada hasta la aparición de la estovaína, siendo practicada entonces por los doctores Enrique B. Barnet y Donato González Mármol. En el VI Congreso Médico Nacional efectuado en ...

  2. Passagem transplacentária e efeitos embriofetais de drogas usadas em anestesia

    OpenAIRE

    Horta, Márcio Leal; Lemonica, Ione Pellegatti

    2002-01-01

    JUSTIFICATIVA E OBJETIVOS: A anestesia da paciente grávida engloba situações diversas e que devem ser analisadas com muita propriedade. Além da exposição do feto e de uma possível ação tóxica dos agentes a serem utilizados na anestesia, devem ser considerados o período gestacional, as características de cada droga e as doses a serem utilizadas. A falta de informações adequadas sobre o risco do uso de drogas na gestação torna difícil ao anestesiologista uma opção segura quando se vê diante da ...

  3. SISTEMA COMPUTARIZADO EN LAZO CERRADO PARA EL SUMINISTRO DE LA ANESTESIA INTRAVENOSA

    Directory of Open Access Journals (Sweden)

    Alberto Vanegas-Saavedra

    2014-12-01

    Full Text Available El sistema de suministro de la anestesia total intravenosa en lazo cerrado es una técnica reciente que ofrece ventajas sobre las técnicas actuales como la estabilidad intraoperatoria y la menor y más segura dosificación. OBJETIVO: El objetivo general de este artículo es el de resumir los hallazgos sobre un nuevo método computarizado sencillo, en lazo cerrado, para suministrar la anestesia total intravenosa de forma automatizada y segura bajo la supervisión permanente del Anestesiólogo. Este sistema se ha desarrollado para la administración de anestesia intravenosa implementando varios subsistemas. Un modelo multicompartimental de distribución de fármacos en el paciente, un algoritmo para determinar la curva de velocidades del hipnótico (propofol a infundir, un protocolo de comunicación para establecer las velocidades de infusión y un lazo de realimentación para controlar la profundidad hipnótica mediante el índice biespectral. RESULTADO: El resultado final ha sido el desarrollo de un instrumento de fácil uso, con una interfaz interactiva, que facilita la operación anestésica por parte del anestesiólogo valiéndose de un computador convencional y un monitor de profundidad hipnótica. CONCLUSIÓN: Se ha implementado una herramienta informática dotada de un modelo farmacocinético multicompartimental de gran interés académico y clínico, que tal y como se ha demostrado de forma cuantitativa, proporciona idénticos resultados a los ofrecidos por equipos comerciales; con importantes ventajas adicionales como una interfaz de usuario interactiva y la posibilidad de administrar anestesia total intravenosa.

  4. CT classification of intra-articular calcaneus fractures

    International Nuclear Information System (INIS)

    Haeberle, H.J.; Minholz, R.; Bader, C.; Tomczak, R.; Rilinger, N.; Friedrich, J.M.; Bauer, G.; Mutschler, W.

    1993-01-01

    93 patients with 102 intraarticular calcaneus fractures (ICF) were examined by CT from 1986 to 1992. The images were evaluated with the use of a modified classification based on the number of fractured heel bone facets (2 facets in 4.8%, 3 facets in 53.9%, 4 facets in 32.3%, comminution in 8.8% of the fractures), the involvement of the calcaneoucuboid joint (60.8%) and the fracture mechanism (tongue-type in 28.4%, joint depression in 62.7%) with the weight-bearing calcaneal compartments taken into special consideration. In that way, each intraarticular calcaneus fracture could be scored, enabling a fast diagnosis comprising factors relevant for the therapy and prognosis. (orig.) [de

  5. Intra-Articular Therapeutic Delivery for Post-Traumatic Osteoarthritis

    Science.gov (United States)

    2017-10-01

    loading and disease progression timeframe in a large animal model in order to outline a pathway to human clinical trials of the treatment method . Our...AWARD NUMBER: W81XWH-14-2-0188 TITLE: Intra-Articular Therapeutic Delivery for Post-Traumatic Osteoarthritis PRINCIPAL INVESTIGATOR: Robert...Intra-Articular Therapeutic Delivery for Post-Traumatic Osteoarthritis 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-14-2-0188 5c. PROGRAM ELEMENT

  6. Avaliação da memória sob anestesia venosa total

    Directory of Open Access Journals (Sweden)

    Gulistan Aktas

    2013-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Neste estudo, objetivamos avaliar a memória implícita e explícita em pacientes submetidos à cirurgia abdominal sob anestesia venosa total (AVT com propofol e remifentanil, na qual o nível de anestesia foi controlado pelo monitoramento do índice bispectral (BIS. MÉTODO: Anestesia venosa total foi administrada a 60 pacientes adultos para obter níveis de BIS de 40-60. Os pacientes foram randomicamente divididos em três grupos, de acordo com as gravações que ouviram. Os pacientes do grupo categoria (CT ouviram uma fita gravada contendo cinco nomes de animais. Os pacientes do grupo recordar palavras (RP ouviram uma fita gravada contendo cinco palavras de frequência média na língua turca, depois de adaptadas. Os pacientes do grupo controle (GC ouviram os sons do mar até o fim da cirurgia. Duas horas após a cirurgia, os testes foram administrados a cada paciente na sala de recuperação para avaliar a memória. RESULTADOS: Houve uma diferença entre os escores dos grupos CT e GC no Miniexame do Estado Mental (MMSE; todos os escores foram > 20. Os resultados dos testes de categoria e recordar palavras, aplicados para avaliar a memória implícita, não foram estatisticamente diferentes entre os grupos. Não houve evidência de memória implícita em nenhum dos pacientes. Um paciente lembrou-se de ouvir "o som de água" como uma prova de memória explícita. Onze pacientes declararam não ter sonhado. CONCLUSÕES: Apesar de não termos encontrado nenhuma evidência de memória implícita sob anestesia adequada com AVT, um paciente apresentou memória explícita. Embora a profundidade adequada da anestesia fornecida pelo monitoramento do BIS corrobore nossos resultados para a memória implícita, ela não explica os resultados para a memória explícita.

  7. Early osteoarthritis and microdialysis: a novel in vivo approach for measurements of biochemical markers in the perisynovium and intraarticularly

    DEFF Research Database (Denmark)

    Helmark, Ida Carøe; Mikkelsen, U R; Krogsgaard, M R

    2010-01-01

    The microdialysis technique was evaluated as a possible method to obtain local measurements of biochemical markers from knee joints with degenerative changes. Seven patients scheduled for arthroscopy of the knee due to minor to moderate degenerative changes had microdialysis catheters inserted...... under ultrasonographic guidance, intraarticularly and in the synovium-close tissue. Catheters were perfused at a rate of 2 μl/min for approximately 100 min with a Ringer solution containing radioactively labeled glucose, and the positions of the catheters were later visualized during arthroscopy. All...

  8. Comparison of hyaluronic acid and PRP intra-articular injection with combined intra-articular and intraosseous PRP injections to treat patients with knee osteoarthritis.

    Science.gov (United States)

    Su, Ke; Bai, Yuming; Wang, Jun; Zhang, Haisen; Liu, Hao; Ma, Shiyun

    2018-05-01

    The aim of this study was to evaluate the benefit provided by intraosseous infiltration combined with intra-articular injection of platelet-rich plasma to treat mild and moderate stages of knee joint degeneration (Kellgren-Lawrence score II-III) compared with other treatments, specifically intra-articular injection of PRP and of HA. Eighty-six patients with grade II to grade III knee OA according to the Kellgren-Lawrence classification were randomly assigned to intra-articular combined with intraosseous injection of PRP (group A), intra-articular PRP (group B), or intra-articular HA (group C). Patients in group A received intra-articular combined with intraosseous injection of PRP (administered twice, 2 weeks apart). Patients in group B received intra-articular injection of PRP every 14 days. Patients in group C received a series of five intra-articular injections of HA every 7 days. All patients were evaluated using the Visual Analogue Scale (VAS) and Western Ontario and McMaster Universities (WOMAC) score before the treatment and at 1, 3, 6, 12, and 18 months after treatment. There were significant improvements at the end of the 1st month. Notably, group A patients had significantly superior VAS and WOMAC scores than were observed in groups B and C. The VAS scores were similar in groups B and group C after the 6th month. Regarding the WOMAC scores, groups B and C differed at the 1st, 3rd, 6th, and 12th months; however, no significant difference was observed at the 18th month. The combination of intraosseous with intra-articular injections of PRP resulted in a significantly superior clinical outcome, with sustained lower VAS and WOMAC scores and improvement in quality of life within 18 months.

  9. Anestesia e síndrome do QT longo Anestesia e síndrome del QT largo Anesthesia and the long QT syndrome

    Directory of Open Access Journals (Sweden)

    Michelle Nacur Lorentz

    2007-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: As disritmias cardíacas são fatores importantes de morbimortalidade no período perioperatório. Dentre as causas de disritmias, a síndrome do QT longo, tanto em sua forma genética como adquirida deve ser lembrada, já que muitos fármacos usados em anestesia, bem como ocorrências no período perioperatório podem prolongar o intervalo QT e precipitar disritmias cardíacas potencialmente malignas. CONTEÚDO: Revisão da síndrome do QT longo (LQTS, abordando suas causas e sua definição, assim como os mecanismos da doença. Além de citar vários fármacos implicados no prolongamento do intervalo QT, as abordagens anestésicas mais adequadas para os pacientes afetados são sugeridas. CONCLUSÃO: A síndrome do QT longo, possível causa de morbimortalidade intra e pós-operatória, pode estar relacionada com fármacos utilizados durante anestesia. Essa condição demanda conhecimento do anestesiologista a fim de evitar desfecho desfavorável do ato operatório.JUSTIFICATIVA Y OBJETIVOS: Las arritmias cardíacas son factores importantes de morbi mortalidad en el período perioperatorio. Entre las causas de arritmias, el síndrome del QT largo, tanto en su forma genética como adquirida debe ser recordado ya que muchos fármacos usados en anestesia, e incidencias en el período perioperatorio pueden prolongar el intervalo QT y precipitar arritmias potencialmente malignas. CONTENIDO: Revisión del Síndrome del QT largo (LQTS, abordando sus causas y definición, y los mecanismos de la enfermedad. Además de citar varios fármacos implicados en el prolongamiento del intervalo QT, los abordajes anestésicos más adecuadas para los pacientes afectados son sugeridas. CONCLUSIÓN: El síndrome del QT largo, posible causa de morbimortalidad intra y postoperatoria, puede estar relacionada a fármacos utilizados durante anestesia. Esa condición demanda conocimiento del anestesiólogo para evitar un desenlace no deseado de

  10. Intraarticular Sprifermin (Recombinant Human Fibroblast Growth Factor 18) in Knee Osteoarthritis

    DEFF Research Database (Denmark)

    Lohmander, L. S.; Hellot, S.; Dreher, D.

    2014-01-01

    Objective. To evaluate the efficacy and safety of intraarticular sprifermin (recombinant human fibroblast growth factor 18) in the treatment of symptomatic knee osteoarthritis (OA). Methods. The study was a randomized, double-blind, placebo-controlled, proof-of-concept trial. Intraarticular...

  11. Listeria monocytogenes septic arthritis following intra-articular yttrium-90 therapy.

    Science.gov (United States)

    Wilson, A P; Prouse, P J; Gumpel, J M

    1984-01-01

    Listeria monocytogenes is a rare cause of septic arthritis, which usually occurs in a host compromised by systemic illness. Intra-articular irradiation with yttrium-90 is generally free of complication. We report a case of intra-articular sepsis of the knee joint by Listeria monocytogenes acquired under unusual circumstances. PMID:6742916

  12. Indications for intra-articular steroid in osteoarthritis of the ankle and ...

    African Journals Online (AJOL)

    The results of treatment with intra-articular steroid in an unselected group of patients with osteo-arthritis of the ankle and metatarsophalangeal joint of the big toe are described. From the results of this trial it is possible to lay down indications for the use of intra-articular steroid in these conditions. In the ankle joint it is ...

  13. Anestesia e apnéia obstrutiva do sono Anestesia y apnea obstructiva del sueño Anesthesia and obstructive sleep apnea

    Directory of Open Access Journals (Sweden)

    Charles Machado

    2006-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A manutenção da permeabilidade das vias aéreas superiores (VAS é fundamental para anestesia e para pacientes com apnéia obstrutiva do sono (AOS. Durante ambos os estados ocorre uma redução do tônus da musculatura faríngea. Identificar pacientes com AOS é importante a fim de prevenir riscos durante o período perioperatório. O objetivo deste trabalho foi apresentar uma revisão sobre a relação entre AOS e anestesia, levando em conta o planejamento da anestesia, enfatizando a importância da identificação da síndrome da apnéia e hipopnéia obstrutiva do sono (SAHOS. CONTEÚDO: A SAHOS ocorre principalmente por colapso total ou parcial da faringe, podendo levar a diminuição na saturação da oxiemoglobina e complicações cardiovasculares. Os principais fatores predisponentes são sexo masculino, obesidade, características crânio e orofaciais. Seu diagnóstico é clínico e polissonográfico, o que também quantifica a gravidade da AOS. Os pacientes com SAHOS especialmente acentuada podem apresentar problemas durante a intubação traqueal e sedação, estando alguns mais susceptíveis à ocorrência de hipóxia e hipercapnia, mesmo na vigência de pulmões normais. Os autores discutem a importância do diagnóstico prévio e tratamento da SAHOS na tentativa de reduzir o risco anestésico. CONCLUSÕES: O diagnóstico e tratamento prévio da SAHOS com pressão positiva contínua nas VAS podem reduzir complicações perioperatórias e influenciar na conduta anestésica e na recuperação pós-anestésica.JUSTIFICATIVA Y OBJETIVOS: El mantenimiento de la permeabilidad de las vías aéreas superiores (VAS es fundamental para la anestesia y para pacientes con apnea obstructiva del sueño (AOS. Durante los de los estados, ocurre una reducción del tono de la musculatura faríngea. Identificar pacientes con AOS es importante para prevenir riesgos durante el período perioperatorio. El objetivo de este

  14. Anestesia venosa total para timectomia em paciente com Miastenia Gravis: relato de caso

    Directory of Open Access Journals (Sweden)

    Rezer Gabrielle

    2003-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Pacientes com doenças neuromusculares, como Miastenia Gravis, respondem de maneira anormal aos anestésicos, conforme a técnica e as drogas administradas. O objetivo deste relato é mostrar um caso de paciente portadora de Miastenia Gravis, submetida a timectomia sob anestesia venosa total com propofol e remifentanil. RELATO DO CASO: Paciente feminina, 52 anos, 72 kg, com história de Miastenia Gravis submetida a timectomia transesternal, sob anestesia venosa total, com o uso de propofol em infusão alvo controlada (3 g.ml-1 e remifentanil contínuo (0,3 µg.kg-1.min-1. Para a intubação traqueal foi utilizada succinilcolina (50 mg, sendo realizada sem dificuldade. Com a finalidade de realizar a analgesia pós-operatória, foram utilizados tramadol (50 mg, cetoprofeno (100 mg e dipirona (1 g, no per-operatório. Após a cirurgia, a infusão de propofol e remifentanil foi encerrada e, 15 minutos depois, a paciente foi extubada. A paciente apresentava-se eupnéica, acordada, sem dor, movimentando membros, com freqüência respiratória de 14 mpm e mantendo saturação de oxigênio de 97%. Permaneceu com cateter nasal de O2 a 2 L.min-1 na UTI intermediária, durante 36 horas, e recebeu alta hospitalar no 4º dia do pós-operatório. CONCLUSÕES: A anestesia venosa total, com agentes anestésicos de curta duração e sem metabólitos ativos, favoreceu a recuperação e a extubação precoce da paciente

  15. Comparison of efficacy of intraarticular application of tenoxicam, bupivacaine and tenoxicam: bupivacaine combination in arthroscopic knee surgery.

    Science.gov (United States)

    Talu, Gül K; Ozyalçin, Süleyman; Koltka, Kemallettin; Ertürk, Engin; Akinci, Ozkan; Aşik, Mehmet; Pembeci, Kamil

    2002-11-01

    Arthroscopic knee surgery is one of the most common surgeries done in outpatient settings; however, postoperative pain is believed to be the major barrier for discharge and early rehabilitation. In this study we evaluated and compared the efficacy of intraarticular application of long-lasting non-steroidal analgesic drug tenoxicam, a long-lasting local anaesthetic bupivacaine and combination of the two on postoperative pain after arthroscopic knee surgery. With the approval of the local ethics committee and signed informed consent of the patients, 75 American Society of Anesthesiologists I-II patients aged between 18 and 65 years going under elective arthroscopic meniscectomy were included in this randomized, blind, prospective study. The patients were divided into three groups: group-T (GT) patients ( n=25) had intraarticular 20 mg of tenoxicam in 20 ml normal saline; group-B (GB) patients ( n=25) had 50 mg bupivacaine in 20 ml normal saline (0.25%); group-BT (GBT) patients ( n=25) had intraarticular 20 mg of tenoxicam and 50 mg bupivacaine (0.25%) in 20 ml normal saline after completion of the surgery and before deflation of the tourniquet. Postoperative analgesia was maintained by intravenous tramadol hydrochloride 50 mg/s at the first 4 h and paracetamol 500 mg and codeine 7.5 mg preparation (Pacofen) as needed (maximum six per day) during the study period. The numeric rating scale (NRS) values were at rest and at active-passive motion at 4, 12, 24 and 48 h, total analgesic consumption, at 4 h for tramadol and at the end of 48 h for oral medication; and patient satisfaction at the end of 48 h was evaluated and recorded. The demographic features of the patients, and tourniquet times, were found to be similar between the groups. Group BT had significantly lower NRS values than GB at 12 h at rest. Group BT was found to have significantly lower NRS values at 4 h compared with GT, and significantly lower NRS values at 12 h compared with GB. Group BT was found to

  16. Pediatric and adolescent intra-articular fractures of the calcaneus

    Directory of Open Access Journals (Sweden)

    Marcel Dudda

    2013-06-01

    Full Text Available Calcaneal fractures in childhood are very rare, whereas particularly intra-articular displaced fractures are not typical in skeletally immature children. Various techniques of osteosynthesis have been described. This study aimed to determine clinical and radiological outcome after surgical treatment of intra-articular calcaneal fractures. Fourteen intra-articular fractures of the calcaneus were included in this retrospective study. Eleven children (2 girls and 9 boys aged 6-16 years (average age 11.5 years underwent surgical treatment. One child sustained a Type II open fracture of both calcanei. All injuries occurred after a high-energy trauma; 3 patients had multiple additional fractures. The clinical and radiological postoperative follow up was an average 44 months. In 4 cases, a reduction through a minimally invasive approach and fixation with K-wires or screws could be achieved. Eleven fractures were treated with open reduction and internal fixation with plate osteosynthesis, K-wires or screws. In one case with open fractures of both heel bones, an additional external fixator was applied. The surgical treatment approach adopted enabled the pre-operative Boehler’s angle (average 16° to be improved to an average 30°. In all cases, except for the patient with open fractures, a good functional result and outcome could be achieved. In calcaneal fractures in childhood, anatomical reduction is the determining factor, as in fractures in adults, whereas the surgical technique seems to have no influence on clinical outcome in children. The wound healing problems that have often been described were not observed in this age group.

  17. Comparison of efficacy of intra-articular morphine and steroid in patients with knee osteoarthritis

    Directory of Open Access Journals (Sweden)

    Serbülent Gökhan Beyaz

    2012-01-01

    Full Text Available Introduction: Primary therapeutic aim in treatment of osteoarthritis of the knee is to relieve the pain of osteoarthritis. The aim of this study was to compare the efficacy of intra-articular triamcinolone with intra-articular morphine in pain relief due to osteoarthritis of the knee in the elderly population. Materials and Methods: Patients between 50 and 80 years of age were randomized into three groups. Group M received morphine plus bupivacaine intra-articularly, Group T received triamcinolone plus bupivacaine intra-articularly, and Group C received saline plus bupivacaine intra-articularly. Patients were evaluated before injection and in 2nd, 4th, 6th, and 12th weeks after injection. First-line supplementary analgesic was oral paracetamol 1500 mg/day. If analgesia was insufficient with paracetamol, oral dexketoprofen trometamol 50 mg/day was recommended to patients. Results: After the intra-articular injection, there was statistically significant decrease in visual analog scale (VAS scores in Groups M and T, when compared to Group C. The decrease of VAS scores seen at the first 2 weeks continued steadily up to the end of 12th week. There was a significant decrease in Groups M and T in the WOMAC scores, when compared to Group C. There was no significant difference in the WOMAC scores between morphine and steroid groups. Significantly less supplementary analgesics was used in the morphine and steroid groups. Conclusion: Intra-articular morphine was as effective as intra-articular triamcinolone for analgesia in patients with osteoarthritis knee. Intra-articular morphine is possibly a better option than intra-articular steroid as it has lesser side effects.

  18. Efeitos fetais e maternos do propofol, etomidato, tiopental e anestesia epidural, em cesariana eletivas de cadelas

    Directory of Open Access Journals (Sweden)

    Lavor Mário Sérgio Lima de

    2004-01-01

    Full Text Available O objetivo deste trabalho foi comparar os efeitos entre os fármacos indutores de anestesia como propofol, etomidato e tiopental, e a anestesia epidural com lidocaína seguida de indução, em cadelas submetidas à cesariana, e seus neonatos. Para tanto, foram utilizadas 20 cadelas e 129 filhotes distribuídos em quatro grupos. No grupo 1 (5 cadelas e 39 neonatos, a indução anestésica foi feita com propofol; no grupo 2 (5 cadelas e 25 neonatos, com etomidato; no grupo 3 (5 cadelas e 26 neonatos com tiopental e no grupo 4, (5 cadelas e 39 neonatos utilizou-se anestesia epidural e indução com halotano através de máscara. Em todos os casos, a medicação pré-anestésica foi feita com midazolam na dose de 0,22mg kg-1 via IM, e a manutenção anestésica com halotano em circuito semifechado e concentração inicial de 3V%. As variáveis avaliadas nas cadelas foram: temperatura retal, freqüência cardíaca, freqüência respiratória, saturação da oxi-hemoglobina (SpO2, pressão arterial média. Para a avaliação dos recém-nascidos, foram mensurados: freqüência cardíaca, esforço respiratório, movimentos musculares, coloração das mucosas e irritabilidade reflexa interpretados através do escore de Apgar modificado, bem como a SpO2 do neonato. Os resultados mostraram que todos os protocolos foram adequados para as mães com mínimos efeitos sistêmicos. Para o neonato, a utilização de anestesia epidural na mãe, seguida de indução e manutenção com halotano foi superior aos protocolos que usaram agentes injetáveis na indução anestésica.

  19. Anestesia em paciente com Distrofia Muscular de Duchenne: relato de caso

    OpenAIRE

    Tonelli,Deoclécio; Pinho,Iglair; Sacco,Paula de Camargo Neves; Vianna,Eduardo Piccinini; Vasconcellos,José Correia de; Souza,Raquel Vasconcelos de; Umakoshi,Sidney

    2003-01-01

    JUSTIFICATIVA E OBJETIVOS: A distrofia muscular de Duchenne é uma afecção recessiva ligada ao cromossomo X, geralmente diagnosticada na infância, acentuando-se progressivamente até agravar a função respiratória. O objetivo deste relato é apresentar um caso de um paciente com distrofia muscular de Duchenne diagnosticada há 2 anos, submetido à postectomia, sob anestesia geral com cetamina S. RELATO DO CASO: Paciente com 9 anos de idade com Distrofia Muscular de Duchenne diagnosticada há 2 anos,...

  20. Os fitoterápicos e a anestesia na cirurgia de ambulatório

    OpenAIRE

    Canário, Catarina Sofia Simão

    2011-01-01

    A utilização de fitoterápicos (medicamentos à base de plantas e substâncias derivadas das plantas) para fins terapêuticos e profiláticos é uma prática frequente nas nossas sociedades. Estes produtos contêm substâncias que podem interagir com os medicamentos usados convencionalmente, nomeadamente com os anestésicos e adjuvantes da anestesia. Contudo, estudos que demonstrem estas interacções são escassos. A presente dissertação tem como objectivo estudar as interacções que podem ocorrer entre o...

  1. Anestesia em paciente com síndrome de Rubinstein-Taybi: relato de caso

    OpenAIRE

    Oliveira, Carlos Rogério Degrandi; Elias, Luciana

    2005-01-01

    JUSTIFICATIVA E OBJETIVOS: A síndrome de Rubinstein-Taybi (SRT) é uma doença genética causada por uma mutação ou apagamento do cromossomo 16, caracterizada por retardo físico e mental, anormalidades craniofaciais e hálux e polegares largos. Há pouca informação sobre esta síndrome na literatura anestésica. O objetivo deste relato foi apresentar a conduta anestésica em paciente submetido à cirurgia odontológica e discutir as características de interesse para a anestesia nesses pacientes. RELATO...

  2. Anestesia del toro bravo. Estudio clínico, cardiorrespiratorio y neurológico

    OpenAIRE

    Muñoz Rascón, Pilar

    2014-01-01

    El toro bravo, tanto por su temperamento como por ser una raza extensiva en semilibertad se asemeja más a los bovinos de vida libre como el búfalo o el bisonte que a los bovinos domésticos. Estos animales, en ocasiones, requieren asistencia veterinaria para la realización de procedimientos medico-quirúrgicos, diagnósticos o de manejo que necesitan de la anestesia como herramienta imprescindible para su realización. La inmovilización de estos animales resulta esencial para minim...

  3. Intraarticular fractures of calcaneus - current concepts of treatment.

    Science.gov (United States)

    Kołodziejski, Paweł; Czarnocki, Łukasz; Wojdasiewicz, Piotr; Bryłka, Krzysztof; Kuropatwa, Krzysztof; Deszczyński, Jarosław

    2014-07-14

    Fractures of calcaneus are the most common among all tarsal bone fractures. Such injuries are most often produced by large forces, while accompanying soft tissue trauma makes them complicated and difficult to treat. Due to complex structure of the foot and talocalcaneal joint all injuries to this area constitute an important orthopedic problem, as improper treatment or lack thereof leads to gait impairment, particularly with regard to moving on uneven surface. In this work we presented the problem of intraarticular calcaneal fractures with particular consideration paid to methods of its treatment. We also mentioned the problem of complications after conservative and surgical treatment as well as methods of their prevention.

  4. Will a single periarticular lidocaine-corticosteroid injection improve the clinical efficacy of intraarticular hyaluronic acid treatment of symptomatic knee osteoarthritis?

    Science.gov (United States)

    Ertürk, Cemil; Altay, Mehmet Akif; Altay, Nuray; Kalender, Ali Murat; Öztürk, İbrahim Avşin

    2016-11-01

    A local injection of corticosteroid-lidocaine into the periarticular soft tissue structures is used commonly for rapid pain relief. It is hypothesized that knee pain associated with knee osteoarthritis would be relieved quickly and effectively in patients receiving intraarticular hyaluronic acid combined with a periarticular lidocaine-corticosteroid injection. To test this hypothesis, the clinical effect of the combined treatment with hyaluronic acid injection alone in patients with symptomatic knee osteoarthritis as compared in this prospective single-blinded randomized trial. This study included 70 patients. Group 1 (n = 35) received intraarticular hyaluronic acid injections only, whereas group 2 (n = 35) received intraarticular hyaluronic acid injections combined with a single local injection of corticosteroid-lidocaine. Injections were administered to the most painful areas of the anterior or posterior medial condyle of the femur or tibia. The outcome was measured by independent assessors (blinded to treatment) using a linear VAS pain scale and WOMAC and HSS knee scores. Assessments were performed at baseline and at 1, 3, 6, 12, 26, and 52 weeks. During the first 3 weeks, group 2 patients showed significantly better all scores than did group 1 patients (p hyaluronic acid alone in patients with knee osteoarthritis and can be considered a useful adjunctive treatment modality. This combined method may provide early return to patient's daily activity. Therapeutic study, Level I.

  5. Usefulness of intra-articular bupivacain and lidocain adjunction in MR or CT arthrography: A prospective study in 148 patients

    International Nuclear Information System (INIS)

    Mosimann, Pascal J.; Richarme, Delphine; Becce, Fabio; Knoepfli, Anne-Sophie; Mino, Vincent; Meuli, Reto; Theumann, Nicolas

    2012-01-01

    Purpose: To evaluate the influence of shorter- and longer-acting intra-articular anaesthetics on post-arthrographic pain. Materials and methods: 154 consecutive patients investigated by MR or CT arthrographies were randomly assigned to one of the following groups: 1 – intra-articular contrast injection only; 2 – lidocain 1% adjunction; or 3 – bupivacain 0.25% adjunction. Pain was assessed before injection, at 15 min, 4 h, 1 day and 1 week after injection by visual analogue scale (VAS). Results: At 15 min, early mean pain score increased by 0.96, 0.24 and 0 in groups 1, 2 and 3, respectively. Differences between groups 1 and 3 and 1 and 2 were statistically significant (p = 0.003 and 0.03, respectively), but not between groups 2 and 3 (p = 0.54). Delayed mean pain score increase was maximal at 4 h, reaching 1.60, 1.22 and 0.29 in groups 1, 2 and 3, respectively. Differences between groups 1 and 2 and 2 and 3 were statistically significant (p = 0.002 and 0.02, respectively), but not between groups 1 and 2 (p = 0.46). At 24 h and 1 week, the interaction of local anaesthetics with increase in pain score was no longer significant. Results were independent of age, gender and baseline VAS. Conclusion: Intra-articular anaesthesia may significantly reduce post-arthrographic pain. Bupivacain seems to be more effective than lidocain to reduce both early and delayed pain

  6. Anestesia subdural após punção peridural: relato de dois casos Anestesia subdural después punción peridural: relato de dos casos Subdural anesthesia after epidural puncture: two case reports

    Directory of Open Access Journals (Sweden)

    Carlos Escobar Vásquez

    2003-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Anestesias condutivas peridurais são realizadas amplamente no nosso meio. A anestesia subdural acidental após punção peridural é uma complicação rara. O objetivo deste relato é descrever dois casos de injeção subdural que coincidentemente ocorreram de forma consecutiva realizadas pelo mesmo anestesiologista. RELATO DOS CASOS: Caso 1: Paciente do sexo masculino, 41 anos, estado físico ASA I, a realizar procedimento cirúrgico de retirada de cálculo renal. Optou-se por anestesia peridural. Após 30 minutos do início da anestesia, o paciente mantinha-se comunicativo mas sonolento com SpO2 de 100%, quando lentamente começou a apresentar diminuição da SpO2 chegando a 80%. Apresentava-se inconsciente com apnéia e anisocoria. A partir deste momento foi levantada hipótese diagnóstica de anestesia subdural acidental. O paciente foi então intubado e mantido em ventilação controlada mecânica. Terminada a cirurgia, foi encaminhado para a sala de recuperação, recebendo alta após 6 horas, sem nenhuma alteração clínico-neurológica. Caso 2: Paciente do sexo feminino, 82 anos, estado físico ASA II, programado para procedimento cirúrgico de fixação de fratura transtrocanteriana. Optou-se por anestesia peridural contínua. Assim como no caso anterior, após 30 minutos, a paciente começou a apresentar diminuição da SpO2 para 90%. Mostrava-se inconsciente e com anisocoria; entretanto, sem apnéia. Optou-se por manter a paciente sob vigilância constante, não sendo necessária intubação. A hipótese diagnóstica aventada também neste caso foi de anestesia subdural acidental. Terminada a cirurgia, a paciente foi encaminhada à sala de recuperação pós-anestésica, tendo alta após 4 horas, sem nenhuma alteração clínico-neurológica. CONCLUSÕES: Anestesia subdural acidental é uma complicação extremamente rara. A hipótese diagnóstica de anestesia subdural acidental, nestes casos, limitou

  7. Complicações neurológicas determinadas pela anestesia subaracnóidea

    Directory of Open Access Journals (Sweden)

    Ganem Eliana Marisa

    2002-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Complicações neurológicas da anestesia subaracnóidea, apesar de raras, podem determinar seqüelas importantes. O objetivo deste estudo é apresentar estas complicações com a finalidade de esclarecer os fatores desencadeantes, o que facilita o diagnóstico das lesões. CONTEÚDO: São apresentadas as seguintes complicações: lesão de nervo desencadeada pela agulha e cateter, cefaléia pós-punção, síndrome da artéria espinhal anterior, hematoma espinhal, meningite bacteriana, meningite asséptica, aracnoidite adesiva, síndrome da cauda eqüina e sintomas neurológicos transitórios. CONCLUSÕES: O conhecimento dos fatores desencadeantes de complicações neurológicas determinadas pela anestesia subaracnóidea pode prevenir as lesões, diagnosticar e tratar mais precocemente e, desse modo, mudar o prognóstico das mesmas.

  8. Anestesia peridural lombar ou bloqueio do plexo lombar combinados à anestesia geral: eficácia e efeitos hemodinâmicos na artroplastia total do quadril Anestesia epidural lumbar o bloqueo del plexo lumbar combinados con la anestesia general: eficacia y efectos hemodinámicos en la artroplastia total de la cadera Epidural lumbar block or lumbar plexus block combined with general anesthesia: efficacy and hemodynamic effects on total hip arthroplasty

    Directory of Open Access Journals (Sweden)

    Leonardo Teixeira Domingues Duarte

    2009-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A anestesia para artroplastia total do quadril (ATQ constitui desafio devido à idade avançada e às doenças associadas dos pacientes. O objetivo do estudo foi avaliar se o bloqueio do plexo lombar combinado à anestesia geral se equivale à anestesia peridural lombar quanto à eficácia do bloqueio nociceptivo, efeitos hemodinâmicos secundários, dificuldade na sua execução e influência no sangramento operatório em pacientes submetidos à ATQ. MÉTODO: Pacientes estado físico ASA I a III foram alocados aleatoriamente nos grupos Peridural e Lombar. No grupo Peridural, foi realizada anestesia peridural lombar contínua com ropivacaína a 0,5% 10 a 15 mL. No grupo Lombar, foi realizado bloqueio do plexo lombar pela via posterior com ropivacaína a 0,5% 0,4 mL.kg-1. Todos os pacientes foram submetidos à anestesia geral. Foram estudados: a dificuldade na execução dos bloqueios, sua eficácia e efeitos hemodinâmicos secundários. RESULTADOS: 41 pacientes foram incluídos no estudo. O tempo para execução do bloqueio peridural foi menor, mas o número de tentativas de posicionamento da agulha foi semelhante nos dois grupos. O bloqueio peridural foi mais eficaz. No grupo Lombar, houve aumento da pressão arterial diastólica e média (PAM e no duplo produto após a incisão e o consumo anestésico durante a operação foi maior. Após o bloqueio, a PAM foi menor nos momentos 50, 60 e 70 minutos após a realização do bloqueio peridural. O sangramento foi semelhante nos dois grupos. CONCLUSÕES: A técnica peridural promoveu bloqueio nociceptivo mais eficaz sem se associar à instabilidade hemodinâmica quando combinada à anestesia geral. O bloqueio do plexo lombar mostrou-se uma técnica útil em combinação com a anestesia geral quando a anestesia peridural estiver contraindicada.JUSTIFICATIVA Y OBJETIVOS: La anestesia para la artroplastia total de la cadera (ATC, constituye un reto a causa de la edad

  9. Anestesia para cirurgia ortopédica em criança com susceptibilidade à hipertermia maligna: relato de caso

    Directory of Open Access Journals (Sweden)

    Gomez Renato Santiago

    2003-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Hipertermia maligna é uma miopatia autossômica dominante desencadeada por anestésicos inalatórios e bloqueadores neuromusculares, como halotano e succinilcolina, causando aumento da temperatura que pode ser fatal sem o tratamento imediato. O objetivo deste relato é descrever a conduta anestésica em uma criança susceptível à hipertermia maligna que foi submetida a procedimento cirúrgico ortopédico. RELATO DO CASO: Paciente do sexo feminino, com 3 anos, portadora de luxação congênita do quadril e susceptibilidade à hipertermia maligna, conforme história de anestesia anterior, foi submetida à correção cirúrgica ortopédica sob anestesia geral, com propofol e fentanil, associada à anestesia peridural lombar. A temperatura da paciente foi monitorizada continuamente durante a cirurgia e no período pós-operatório. A paciente apresentou recuperação pós-operatória sem intercorrências e recebeu alta hospitalar após cinco dias. CONCLUSÕES: A combinação de anestesia regional e venosa para o procedimento cirúrgico proposto em paciente com susceptibilidade à hipertermia maligna permitiu a condução anestésica com segurança.

  10. Intraarticular and intravenous administration of 99MTc-HMPAO-labeled human mesenchymal stem cells (99MTC-AH-MSCS): In vivo imaging and biodistribution

    International Nuclear Information System (INIS)

    Meseguer-Olmo, Luis; Montellano, Antonio Jesús; Martínez, Teresa; Martínez, Carlos M.; Revilla-Nuin, Beatriz; Roldán, Marta; Mora, Cristina Fuente; López-Lucas, Maria Dolores; Fuente, Teodomiro

    2017-01-01

    Introduction: Therapeutic application of intravenous administered (IV) human bone marrow-derived mesenchymal stem cells (ahMSCs) appears to have as main drawback the massive retention of cells in the lung parenchyma, questioning the suitability of this via of administration. Intraarticular administration (IAR) could be considered as an alternative route for therapy in degenerative and traumatic joint lesions. Our work is outlined as a comparative study of biodistribution of 99m Tc-ahMSCs after IV and IAR administration, via scintigraphic study in an animal model. Methods: Isolated primary culture of adult human mesenchymal stem cells was labeled with 99m Tc-HMPAO for scintigraphic study of in vivo distribution after intravenous and intra-articular (knee) administration in rabbits. Results: IV administration of radiolabeled ahMSCs showed the bulk of radioactivity in the lung parenchyma while IAR images showed activity mainly in the injected cavity and complete absence of uptake in pulmonary bed. Conclusions: Our study shows that IAR administration overcomes the limitations of IV injection, in particular, those related to cells destruction in the lung parenchyma. After IAR administration, cells remain within the joint cavity, as expected given its size and adhesion properties. Advances in knowledge: Intra-articular administration of adult human mesenchymal stem cells could be a suitable route for therapeutic effect in joint lesions. Implications for patient care: Local administration of adult human mesenchymal stem cells could improve their therapeutic effects, minimizing side effects in patients.

  11. Clinical characteristics of pain originating from intra-articular structures of the knee joint in patients with medial knee osteoarthritis.

    Science.gov (United States)

    Ikeuchi, Masahiko; Izumi, Masashi; Aso, Koji; Sugimura, Natsuki; Tani, Toshikazu

    2013-01-01

    Although disease progression of osteoarthritis has been well documented, pain pathophysiology is largely unknown. This study was designed with two purposes: 1) to characterize patients with knee pain predominantly originating from intra-articular structures and 2) to describe the location and pattern of their pain. 103 patients with medial knee osteoarthritis underwent an intra-articular injection of local anesthetics (joint block). At least 70% pain relief was defined as positive for the joint block, while less than 50% as negative. Pain characteristics in patients positive for joint block were evaluated in detail using a knee pain map. Sixty three knees (61%) were positive and 33 knees (32%) were negative. Patients negative for the joint block were significantly higher age, suffered for longer time, and complained more diffuse pain. Although pain at anterior medial area during walk was the most common finding, pain characteristics differed among different knee areas. The characteristics of joint pain are widely variable even in patients with similar radiological features. Extra-articular sources are not negligible especially in older patients with a long history of diffuse pain. Differences in pain characteristics among knee areas should be taken into account when examining the pain source.

  12. Development and in situ application of an adjustable aiming device to guide extra- to intraarticular tibial tunnel drilling for the insertion of the cranial cruciate ligament in dogs.

    Science.gov (United States)

    Winkels, Philipp; Werner, Hinnerk; Grevel, Vera; Oechtering, Gerhard; Böttcher, Peter

    2010-04-01

    To develop and test an arthroscopic aiming device for extra- to intraarticular tibial tunnel drilling emerging at the center of the tibial insertion (CenterTib) of the cranial cruciate ligament (CCL) in medium to large breed dogs. Descriptive experimental study. Fifty-two cadaveric hind limbs of dogs >or=20 kg BW. The mediolateral position and craniocaudal position (ccPos) of CenterTib in relation to the caudomedial meniscotibial ligament were measured on photographs of 46 dissected tibial plateaus. The proximal tibial depth (TibDepth) was determined on lateral radiographs and its correlation with ccPos was assessed using linear regression analysis. Extra- to intraarticular arthroscopic tibial tunnel drilling was performed in 6 independent cadaveric stifles. A C-guide with an adjustable craniocaudal offset was constructed and adjusted according to ccPos estimated based on TibDepth. The position of the resulting bone tunnels was compared with the position of the CenterTib. Pearson's correlation between TibDepth and ccPos was strong (R=0.86; P<.001). ccPos (y) as a function of TibDepth (x) can be expressed as y=-4.8+0.3x. Arthroscopic tunnel drilling resulted in a median deviation of the drill tunnels around the CenterTib of 1 mm. The regression equation and aiming device permit localization and targeting of CenterTib during extra- to intraarticular tibial bone tunnel drilling in vitro. The proposed technique may reduce tibial tunnel misplacement when performing intraarticular CCL repair using a tibial bone tunnel.

  13. Hipertensão arterial sistêmica e anestesia Hipertensión arterial sistémica y anestesia Systemic hypertension and anesthesia

    Directory of Open Access Journals (Sweden)

    Michelle Nacur Lorentz

    2005-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Devido à grande prevalência da hipertensão arterial sistêmica na população e a falta de consenso sobre que níveis pressóricos o anestesiologista deve aceitar para induzir uma anestesia para cirurgia eletiva, realizou-se uma revisão na literatura que trata da associação hipertensão arterial e anestesia. Considerando que a suspensão de uma cirurgia implica em gastos, o que torna a Medicina cada vez mais cara, e que, por outro lado, o ato anestésico deve ser realizado com a maior segurança possível, o objetivo desse trabalho foi analisar as evidências da literatura que possam nortear a prática clínica. CONTEÚDO: O artigo apresenta incidência e classificação da hipertensão arterial sistêmica além de relatar e comentar trabalhos relevantes que abordam a hipertensão arterial no paciente cirúrgico. CONCLUSÕES: Ainda não estão estabelecidos quais níveis máximos de pressão são compatíveis com uma cirurgia eletiva, sendo que, atualmente, os critérios para a suspensão da cirurgia no paciente hipertenso mal controlado são muito mais baseados em dados empíricos que em evidências. Existe uma tendência em postergar a cirurgia quando a PA é superior a 180/110 mmHg, mas cada caso deve ser analisado isoladamente, valorizando mais lesões em órgãos alvo que a pressão arterial propriamente dita.JUSTIFICATIVA Y OBJETIVOS: Debido a la grande superioridad de la hipertensión arterial sistémica en la población y la falta de acuerdo sobre que niveles presóricos el anestesiologista debe aceptar para inducir una anestesia para cirugía electiva, se realizó una revisión en la literatura que trata de la asociación hipertensión arterial y anestesia. Considerando que la suspensión de una cirugía implica en gastos, lo que hace la Medicina cada vez más cara, y que, por otro lado, el acto anestésico debe ser realizado con la mayor seguridad posible, la finalidad de ese trabajo fue analizar las

  14. Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent

    Directory of Open Access Journals (Sweden)

    Murat Tonbul

    2014-01-01

    Full Text Available Osteoarthritis is a chronic disorder characterized by joint cartilage degeneration with concomitant changes in the synovium and subchondral bone metabolism. Many conservative treatment modalities, one of which is intra-articular injections, have been described for the treatment of this disorder. Traditionally, hyaluranic acid and corticosteroids are the agents that have been used for this purpose. Recently, polyacrylamide hydrogels are being used widely. Biocompatibility, nonbioabsorbability, and anti-infectious effect obtained by silver addition made polyacrylamide hydrogels more popular. In this paper, we present a case and the method of our management, in whom host tissue reaction (foreign body granuloma, edema, inflammation, and redness induration has been observed, as the first and unique adverse effect reported in the literature.

  15. Skin Necrosis from Intra-articular Hyaluronic Acid Injection.

    Science.gov (United States)

    Kim, Whan B; Alhusayen, Raed O

    2015-01-01

    Tissue necrosis is a rare yet potentially serious complication of intra-articular (IA) hyaluronic acid (HA) injections for treatment of knee osteoarthritis. To report a case of a patient with cutaneous necrosis after IA HA injection for treatment of knee osteoarthritis, presenting as a livedoid violaceous patch on the right knee. We report a case of cutaneous necrosis as a rare complication of IA HA injection for treatment of knee osteoarthritis. A literature review was undertaken of similar cases. Use of HA IA injections in the treatment of osteoarthritis can result in similar skin necrosis at uncommon anatomic locations corresponding to the site of HA injection. Although tissue necrosis is a rare complication, physicians need to be aware of this possibility as a complication of HA IA injections in the treatment of osteoarthritis and should be mindful of potential treatment options to manage this adverse event. © 2014 Canadian Dermatology Association.

  16. Operative treatment of the displaced intraarticular fractures of the calcaneus

    Directory of Open Access Journals (Sweden)

    Popović Zoran

    2003-01-01

    Full Text Available Most calcaneal fractures occur in male industrial workers, having significant economic repercussions. Although current operative treatment has improved the outcome of the treatment in many patients, there is still no consensus on the classification, treatment, operative technique, or postoperative management. Computed tomographic scanning has improved our understanding of these fractures substantially, and has allowed the consistent analysis of the results of the treatment. The focus of current treatment is on the operative methods, internal fixation by leg-screw and plate through the lateral Kocher approach. Between April 1998 and July 2002, we treated operatively 6 displaced intraarticular fractures of the calcaneus. A lateral Kocher incision, leg-screw, and plate fixation were used. Neither infection, nor nonunion, or malunion occurred. All the patients presently have painless foot, use normal footwear, and are capable of normal activities.

  17. Biomechanical comparison of orthogonal versus parallel double plating systems in intraarticular distal humerus fractures

    Directory of Open Access Journals (Sweden)

    Ata C. Atalar

    2017-01-01

    Conclusion: Our study showed that both plating systems had similar biomechanical stabilities when anatomic plates with distal locking screws were used in intraarticular distal humerus fractures in artificial humerus models.

  18. Accuracy of magnetic resonance in identifying traumatic intraarticular knee lesions

    International Nuclear Information System (INIS)

    Vaz, Carlos Eduardo Sanches; Camargo, Olavo Pires de; Santana, Paulo Jose de; Valezi, Antonio Carlos

    2005-01-01

    Purpose: To evaluate the diagnostic accuracy of magnetic resonance imaging of the knee in identifying traumatic intraarticular knee lesions. Method: 300 patients with a clinical diagnosis of traumatic intraarticular knee lesions underwent prearthoscopic magnetic resonance imaging. The sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio for a positive test, likelihood ratio for a negative test, and accuracy of magnetic resonance imaging were calculated relative to the findings during arthroscopy in the studied structures of the knee (medial meniscus, lateral meniscus, anterior cruciate ligament, posterior cruciate ligament, and articular cartilage). Results: Magnetic resonance imaging produced the following results regarding detection of lesions: medial meniscus: sensitivity 97.5%, specificity 92.9%, positive predictive value 93.9%, positive negative value 97%, likelihood positive ratio 13.7, likelihood negative ratio 0.02, and accuracy 95.3%; lateral meniscus: sensitivity 91.9%, specificity 93.6%, positive predictive value 92.7%, positive negative value 92.9%, likelihood positive ratio 14.3, likelihood negative ratio 0.08, and accuracy 93.6%; anterior cruciate ligament: sensitivity 99.0%, specificity 95.9%, positive predictive value 91.9%, positive negative value 99.5%, likelihood positive ratio 21.5, likelihood negative ratio 0.01, and accuracy 96.6%; posterior cruciate ligament: sensitivity 100%, specificity 99%, positive predictive value 80.0%, positive negative value 100%, likelihood positive ratio 100, likelihood negative ratio 0.01, and accuracy 99.6%; articular cartilage: sensitivity 76.1%, specificity 94.9%, positive predictive value 94.7%, positive negative value 76.9%, likelihood positive ratio 14.9, likelihood negative ratio 0.25, and accuracy 84.6%. Conclusion: Magnetic resonance imaging is a satisfactory diagnostic tool for evaluating meniscal and ligamentous lesions of the knee, but it is unable to clearly

  19. Accuracy of magnetic resonance in identifying traumatic intraarticular knee lesions

    Directory of Open Access Journals (Sweden)

    Vaz Carlos Eduardo Sanches

    2005-01-01

    Full Text Available PURPOSE: To evaluate the diagnostic accuracy of magnetic resonance imaging of the knee in identifying traumatic intraarticular knee lesions. METHOD: 300 patients with a clinical diagnosis of traumatic intraarticular knee lesions underwent prearthoscopic magnetic resonance imaging. The sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio for a positive test, likelihood ratio for a negative test, and accuracy of magnetic resonance imaging were calculated relative to the findings during arthroscopy in the studied structures of the knee (medial meniscus, lateral meniscus, anterior cruciate ligament, posterior cruciate ligament, and articular cartilage. RESULTS: Magnetic resonance imaging produced the following results regarding detection of lesions: medial meniscus: sensitivity 97.5%, specificity 92.9%, positive predictive value 93.9%, positive negative value 97%, likelihood positive ratio 13.7, likelihood negative ratio 0.02, and accuracy 95.3%; lateral meniscus: sensitivity 91.9%, specificity 93.6%, positive predictive value 92.7%, positive negative value 92.9%, likelihood positive ratio 14.3, likelihood negative ratio 0.08, and accuracy 93.6%; anterior cruciate ligament: sensitivity 99.0%, specificity 95.9%, positive predictive value 91.9%, positive negative value 99.5%, likelihood positive ratio 21.5, likelihood negative ratio 0.01, and accuracy 96.6%; posterior cruciate ligament: sensitivity 100%, specificity 99%, positive predictive value 80.0%, positive negative value 100%, likelihood positive ratio 100, likelihood negative ratio 0.01, and accuracy 99.6%; articular cartilage: sensitivity 76.1%, specificity 94.9%, positive predictive value 94.7%, positive negative value 76.9%, likelihood positive ratio 14.9, likelihood negative ratio 0.25, and accuracy 84.6%. CONCLUSION: Magnetic resonance imaging is a satisfactory diagnostic tool for evaluating meniscal and ligamentous lesions of the knee, but it is

  20. Anestesia peridural contínua para cesariana em paciente com arterite de Takayasu: relato de caso Anestesia peridural continua para cesárea en paciente con arteritis de Takayasu: relato de caso Continuous epidural anesthesia for cesarean section in a patient with Takayasu’s arteritis: case report

    Directory of Open Access Journals (Sweden)

    Aloísio Cerqueira Buettel

    2002-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Anestesia peridural contínua com titulação das doses de anestésico local proporciona eficácia e segurança em pacientes que não toleram flutuações da pressão arterial. O objetivo deste relato é apresentar um caso em que foi utilizada com sucesso anestesia peridural contínua para cesariana em paciente com arterite de Takayasu. RELATO DO CASO: Paciente primigesta, 25 anos, 63 kg, portadora de arterite de Takayasu, com 34-35 semanas de gestação, apresentando sofrimento fetal agudo, PA de 155/85 mmHg, FC de 92 bpm, com ausência de pulsos carotídeos, assim como nos membros superiores e do membro inferior direito. Apresentava apenas pulso poplíteo esquerdo palpável. Foi realizado bloqueio peridural contínuo com doses fracionadas de 25 mg de bupivacaína a 0,5% com epinefrina (1:200.000, a intervalos de 5 em 5 minutos até um total de 100 mg, associando-se 2 mg de morfina e 100 µg de fentanil. CONCLUSÕES: A anestesia peridural contínua com doses tituladas de bupivacaína a 0,5% com epinefrina pode ser utilizada em pacientes com Arterite de Takayasu, tomando-se as medidas de precaução com portadoras dessa doença.JUSTIFICATIVA Y OBJETIVOS: Anestesia peridural continua con titulación de las dosis de anestésico local proporciona eficacia y seguridad en pacientes que no toleran flutuaciones de la presión arterial. El objetivo de este relato es presentar un caso en que fue utilizado con suceso anestesia peridural continua para cesárea en paciente con arteritis de Takayasu. RELATO DEL CASO: Paciente primigesta, 25 años, 63 kg, portadora de Arteritis de Takayasu, con 34-35 semanas de gestación, presentando sufrimiento fetal agudo, PA de 155/85 mmHg, FC de 92 bpm, con ausencia de pulsos carotídeos, así como en los miembros superiores y del miembro inferior derecho. Presentaba apenas pulso poplíteo izquierdo palpable. Fue realizado bloqueo peridural continuo con dosis fraccionadas de 25 mg de bupivaca

  1. Intra-articular findings in symptomatic minor instability of the lateral elbow (SMILE).

    Science.gov (United States)

    Arrigoni, Paolo; Cucchi, Davide; D'Ambrosi, Riccardo; Butt, Usman; Safran, Marc R; Denard, Patrick; Randelli, Pietro

    2017-07-01

    Lateral epicondylitis is generally considered an extra-articular condition. The role of minor instability in the aetiology of lateral elbow pain has rarely been considered. The aim of this study was to evaluate the correlation of lateral ligamentous laxity with aspects of intra-articular lateral elbow pathology and investigate the role of minor instability in lateral elbow pain. Thirty-five consecutive patients aged between 20 and 60 years with recalcitrant lateral epicondylitis who had failed conservative therapy and had no previous trauma or overt instability, were included. The presence of three signs of lateral ligamentous patholaxity and five intra-articular findings were documented during arthroscopy. The relative incidence of each of these was calculated, and the correlation between patholaxity and intra-articular pathology was evaluated. At least one sign of lateral ligamentous laxity was observed in 48.6% of the studied cohort, and 85.7% demonstrated at least one intra-articular abnormal finding. Radial head ballottement was the most common sign of patholaxity (42.9%). Synovitis was the most common intra-articular aspect of pathology (77.1%), followed by lateral capitellar chondropathy (40.0%). A significant correlation was found between the presence of lateral ligamentous patholaxity signs and capitellar chondropathy (p = 0.0409), as well as anteromedial synovitis (p = 0.0408). Almost one half of patients suffering from recalcitrant lateral epicondylitis display signs of lateral ligamentous patholaxity, and over 85% demonstrate at least one intra-articular abnormality. The most frequent intra-articular findings are synovitis and lateral capitellar chondropathy, which correlate significantly with the presence of lateral ligamentous patholaxity. The fact that several patients demonstrated multiple intra-articular findings in relation to laxity provides support to a sequence of pathologic changes that may result from a symptomatic minor instability of

  2. Intra-articular ganglion cysts of the knee: clinical and MR imaging features

    Energy Technology Data Exchange (ETDEWEB)

    Kim, M.G.; Cho, W.H. [Dept. of Radiology, Sanggye Paik Hospital, Inje University, Seoul (Korea); Kim, B.H.; Choi, J.A.; Lee, N.J.; Chung, K.B. [Dept. of Diagnostic Radiology, College of Medicine, Korea University, Seoul (Korea); Choi, Y.S.; Cho, S.B. [Dept. of Radiology, School of Medicine, Eulji University, Seoul (Korea); Lim, H.C. [Dept. of Orthopedic Surgery, College of Medicine, Korea University, Seoul (Korea)

    2001-05-01

    The purpose of this study was to present clinical and MR imaging features of intra-articular ganglion cysts of the knee. Retrospective review of 1685 consecutive medical records and MR examinations of the knee performed at three imaging centers allowed identification of 20 patients (13 men and 7 women; mean age 35 years), in whom evidence of intra-articular ganglion cyst was seen. Of the 20 ganglion cysts, 5 were found in the infrapatellar fat pad, 10 arose from the posterior cruciate ligament, and 5 from the anterior cruciate ligament. Three of five patients with ganglion cyst in the infrapatellar fat pad had a palpable mass. In 7 of 15 patients with ganglion cyst in the intercondylar notch, exacerbation of pain occurred in a squatting position. On four MR arthrographies, ganglion cysts were an intra-articular round, lobulated, low signal intensity lesion. Five cases of fat-suppressed contrast-enhanced T1-weighted SE images demonstrated peripheral thin rim enhancement. The clinical presentation of intra-articular ganglion cyst is varied according to its intra-articular location. The MR appearance of intra-articular ganglion cyst is characteristic and usually associated with the cruciate ligament or the infrapatellar fat pad. Magnetic resonance arthrography has no definite advantage over conventional MR in the evaluation of the lesion. For intra-articular ganglion cyst in the infrapatellar fat pad, fat-suppressed contrast-enhanced MR imaging could be useful, because a thin, rim-enhancing feature of intra-articular ganglion cyst allows it to be distinguished from synovial hemangioma and synovial sarcoma. (orig.)

  3. Diagnosis and management of an intra-articular foreign body in the foot.

    LENUS (Irish Health Repository)

    Mulhall, K J

    2002-10-01

    We describe a case of a small intra-articular foreign body in the foot presenting 48 hours following injury, which at operation showed early evidence of septic arthritis. It is essential to accurately localise periarticular foreign bodies in the foot and proceed to arthrotomy and debridement in all cases where there is radiological or clinical evidence to suggest intra-articular retention of a foreign body.

  4. Cardiovascular effects of local anesthesia with vasoconstrictor during dental extraction in coronary patients

    OpenAIRE

    Conrado, Valeria C. L. S.; Andrade, Januário de; Angelis, Gabriella A. M. C. de; Andrade, Ana Carolina P. de; Timerman, Lilia; Andrade, Mercedes M.; Moreira, Dalmo R.; Sousa, Amanda G. M. R.; Sousa, J. Eduardo M. R.; Piegas, Leopoldo S.

    2007-01-01

    OBJETIVO: Avaliar a ocorrência de variáveis detectoras de isquemia miocárdica, durante ou após o tratamento odontológico, sob anestesia com vasoconstritor (adrenalina). MÉTODOS: Foram incluídos 54 pacientes coronariopatas submetidos a exodontia sob anestesia local com ou sem vasoconstritor, divididos em dois grupos (sorteio por envelope): grupo I, composto por 27 que receberam anestésico com vasoconstritor; e grupo II, composto por 27 que receberam anestésico sem vasoconstritor. Todos os paci...

  5. Feasibility of ultrasound-guided intraarticular contrast injection for MR arthrography

    Energy Technology Data Exchange (ETDEWEB)

    Baek, Soo Jin; Lee, Jong Min; Kang, Duck Sick [Kyungpook National University School of Medicine, Daegu (Korea, Republic of)

    2005-07-15

    To assess the feasibility of ultrasound-guided intraarticular contrast injection using the posterior approach for MR arthrography. Between June 2002 and October 2004, 132 patients (29 female, 103 male: mean age, 33.6 years) underwent ultrasound-guided intraarticular contrast media injection (40 ml saline + 10 ml 2% lidocaine + 0.2 ml gadopentetate dimeglumine + 0.4 ml epinephrine) for MR arthrography. The patients were classified into four groups, viz. the no leakage group, the minor leakage with successful intraarticular injection group, the major leakage with unsuccessful intraarticular injection group, and the injection failure group. The 'no leakage' and 'minor leakage' groups were considered to be technical successes, while the 'major leakage' and 'injection failure' groups were regarded as technical failures. The technical success rate of ultrasound-guided intraarticular contrast injection using the posterior approach for MR Arthrography was 99.2% (131/132 patients) and one patients 0.7% (1/132 patients) was included in the 'major leakage' group. Ultrasound-guided intraarticular contrast injection using the posterior approach for MR arthrography was feasible with a high success rate.

  6. Feasibility of ultrasound-guided intraarticular contrast injection for MR arthrography

    International Nuclear Information System (INIS)

    Baek, Soo Jin; Lee, Jong Min; Kang, Duck Sick

    2005-01-01

    To assess the feasibility of ultrasound-guided intraarticular contrast injection using the posterior approach for MR arthrography. Between June 2002 and October 2004, 132 patients (29 female, 103 male: mean age, 33.6 years) underwent ultrasound-guided intraarticular contrast media injection (40 ml saline + 10 ml 2% lidocaine + 0.2 ml gadopentetate dimeglumine + 0.4 ml epinephrine) for MR arthrography. The patients were classified into four groups, viz. the no leakage group, the minor leakage with successful intraarticular injection group, the major leakage with unsuccessful intraarticular injection group, and the injection failure group. The 'no leakage' and 'minor leakage' groups were considered to be technical successes, while the 'major leakage' and 'injection failure' groups were regarded as technical failures. The technical success rate of ultrasound-guided intraarticular contrast injection using the posterior approach for MR Arthrography was 99.2% (131/132 patients) and one patients 0.7% (1/132 patients) was included in the 'major leakage' group. Ultrasound-guided intraarticular contrast injection using the posterior approach for MR arthrography was feasible with a high success rate

  7. Biodistribution and Immunogenicity of Allogeneic Mesenchymal Stem Cells in a Rat Model of Intraarticular Chondrocyte Xenotransplantation

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    Maribel Marquina

    2017-11-01

    Full Text Available Xenogeneic chondrocytes and allogeneic mesenchymal stem cells (MSC are considered a potential source of cells for articular cartilage repair. We here assessed the immune response triggered by xenogeneic chondrocytes when injected intraarticularly, as well as the immunoregulatory effect of allogeneic bone marrow-derived MSC after systemic administration. To this end, a discordant xenotransplantation model was established by injecting three million porcine articular chondrocytes (PAC into the femorotibial joint of Lewis rats and monitoring the immune response. First, the fate of MSC injected using various routes was monitored in an in vivo imaging system. The biodistribution revealed a dependency on the injection route with MSC injected intravenously (i.v. succumbing early after 24 h and MSC injected intraperitoneally (i.p. lasting locally for at least 5 days. Importantly, no migration of MSC to the joint was detected in rats previously injected with PAC. MSC were then administered either i.v. 1 week before PAC injection or i.p. 3 weeks after to assess their immunomodulatory function on humoral and adaptive immune parameters. Anti-PAC IgM and IgG responses were detected in all PAC-injected rats with a peak at week 2 postinjection and reactivity remaining above baseline levels by week 18. IgG2a and IgG2b were the predominant and long-lasting IgG subtypes. By contrast, no anti-MSC antibody response was detected in the cohort injected with MSC only, but infusion of MSC before PAC injection temporarily augmented the anti-PAC antibody response. Consistent with a cellular immune response to PAC in PAC-injected rats, cytokine/chemokine profiling in serum by antibody array revealed a distinct pattern relative to controls characterized by elevation of multiple markers at week 2, as well as increases in proliferation in draining lymph nodes. Notably, systemic administration of allogeneic MSC under the described conditions did not diminish the immune

  8. Anestesia tópica asociada a la técnica de faco - prechop Topical anestesia associated to phaco-prechop technique

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    Juan Raúl Hernández Silva

    2010-01-01

    Full Text Available OBJETIVO: Describir los resultados encontrados en pacientes operados de catarata por faco-prechop con el uso de la anestesia tópica. MÉTODOS: Se realizó un estudio observacional descriptivo prospectivo, de 30 ojos (19 pacientes atendidos en el Centro de Microcirugía Ocular del Instituto Cubano de Oftalmología «Ramón Pando Ferrer» operados de catarata mediante Facoemulsificación por técnica de prechop, en los cuales se utilizó anestesia tópica durante la cirugía en el período comprendido de julio a septiembre de 2009. A los mismos se les realizó microscopía endotelial antes y después de la cirugía con el objetivo de determinar las modificaciones en la densidad celular. Se evaluó la presencia de dolor, así como el confort del cirujano en una escala de satisfacción. Se analizaron las variables edad, promedio celular, dolor, confort del cirujano y mejor agudeza visual corregida pre y posoperatoria. La información se procesó a través de frecuencias absolutas, relativas, media y prueba T de Student. RESULTADOS: La edad media de los pacientes fue de 62 años con un mínimo de 46 y un máximo de 94. La pérdida celular fue mínima. Un escaso número de pacientes manifestó dolor en algún momento de la cirugía, por lo que el confort del cirujano no se afectó de manera significativa durante el acto quirúrgico. Se encontró una ganancia visual de cinco líneas en la escala de Snellen. CONCLUSIONES: Los anestésicos tópicos en la cirugía de catarata evidenciaron ser de muy buena utilidad en nuestra técnica, lo cual no nos llevó al uso de otras vías anestésicas más invasivas para los pacientes.OBJECTIVE: To describe the results found in patients operated from cataract by the Phaco-Prechop technique using the topical anesthesia. METHODS: A prospective, observational and descriptive study was performed in 30 eyes (19 patients, seen at the Center of Ocular Microsurgery of "Ramón Pando Ferrer" Cuban Institute of Ophthalmology

  9. A comparison of intraarticular lumbar facet joint steroid injections and lumbar facet joint radiofrequency denervation in the treatment of low back pain: a randomized, controlled, double-blind trial.

    Science.gov (United States)

    Lakemeier, Stefan; Lind, Marcel; Schultz, Wolfgang; Fuchs-Winkelmann, Susanne; Timmesfeld, Nina; Foelsch, Christian; Peterlein, Christian D

    2013-07-01

    Lumbar facet joint degeneration is a source of chronic low back pain, with an incidence of 15% to 45% among patients with low back pain. Various therapeutic techniques in the treatment of facet-related pain have been described in the literature, including intraarticular lumbar facet joint steroid injections and radiofrequency denervation. In this study, we compared the effectiveness of intraarticular facet joint steroid injections and radiofrequency denervation. Our randomized, double-blind, controlled study included patients who received intraarticular steroid infiltrations in the lumbar facet joints (L3/L4-L5/S1) and patients who underwent radiofrequency denervation of L3/L4-L5/S1 segments. The inclusion criteria were based first on magnetic resonance imaging findings showing hypertrophy of the facet joints L3/L4-L5/S1 and a positive response to an intraarticular test infiltration of the facet joints L3/L4-L5/S1 with local anesthetics. The primary end point was the Roland-Morris Questionnaire. Secondary end points were the visual analog scale and the Oswestry Disability Index. All outcome assessments were performed at baseline and at 6 months. Fifty-six patients were randomized; 24 of 29 patients in the steroid injection group and 26 of 27 patients in the denervation group completed the 6-month follow-up. Pain relief and functional improvement were observed in both groups. There were no significant differences between the 2 groups for the primary end point (95% confidence interval [CI], -3 to 4) and for both secondary end points (95% CI for visual analog scale, -2 to 1; 95% CI for Oswestry Disability Index, -18 to 0). Intraarticular steroid infiltration or radiofrequency denervation appear to be a managing option for chronic function-limiting low back pain of facet origin with favorable short- and midterm results in terms of pain relief and function improvement, but improvements were similar in both groups.

  10. Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model.

    Science.gov (United States)

    Desando, Giovanna; Cavallo, Carola; Sartoni, Federica; Martini, Lucia; Parrilli, Annapaola; Veronesi, Francesca; Fini, Milena; Giardino, Roberto; Facchini, Andrea; Grigolo, Brunella

    2013-01-29

    Cell therapy is a rapidly growing area of research for the treatment of osteoarthritis (OA). This work is aimed to investigate the efficacy of intra-articular adipose-derived stromal cell (ASC) injection in the healing process on cartilage, synovial membrane and menisci in an experimental rabbit model. The induction of OA was performed surgically through bilateral anterior cruciate ligament transection (ACLT) to achieve eight weeks from ACLT a mild grade of OA. A total of 2×10⁶ and 6×10⁶ autologous ASCs isolated from inguinal fat, expanded in vitro and suspended in 4% rabbit serum albumin (RSA) were delivered in the hind limbs; 4% RSA was used as the control. Local bio-distribution of the cells was verified by injecting chloro-methyl-benzamido-1,1'-dioctadecyl-3,3,3'3'-tetra-methyl-indo-carbocyanine per-chlorate (CM-Dil) labeled ASCs in the hind limbs. Cartilage and synovial histological sections were scored by Laverty's scoring system to assess the severity of the pathology. Protein expression of some extracellular matrix molecules (collagen I and II), catabolic (metalloproteinase-1 and -3) and inflammatory (tumor necrosis factor- α) markers were detected by immunohistochemistry. Assessments were carried out at 16 and 24 weeks. Labeled-ASCs were detected unexpectedly in the synovial membrane and medial meniscus but not in cartilage tissue at 3 and 20 days from ASC-treatment. Intra-articular ASC administration decreases OA progression and exerts a healing contribution in the treated animals in comparison to OA and 4% RSA groups. Our data reveal a healing capacity of ASCs in promoting cartilage and menisci repair and attenuating inflammatory events in synovial membrane inhibiting OA progression. On the basis of the local bio-distribution findings, the benefits obtained by ASC treatment could be due to a trophic mechanism of action by the release of growth factors and cytokines.

  11. Padrões de ventilação em anestesia: estudo retrospectivo

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    Vieira Joaquim Edson

    2002-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Alterações da mecânica pulmonar, diminuição da Capacidade Residual Funcional e formação de atelectasias têm sido descritas durante anestesia geral. O objetivo desta investigação foi avaliar de forma retrospectiva os padrões de ventilação mecânica adotados nas salas operatórias do Instituto Central do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP. MÉTODO: Foram registrados dados de 240 pacientes sob anestesia geral, curarizados em ventilação mecânica. Foram observados os padrões de ventilação aplicados: volume corrente em ml (VC, freqüência respiratória por minuto, pressões de vias aéreas em cmH2O e fluxo de gases frescos em L.min-1, SpO2 e P ET CO2. Dados demográficos: sexo, idade, peso, altura foram registrados e calculado o índice de massa corpórea (IMC. Os pacientes foram separados em grupos quanto ao IMC em: 30 kg/m². RESULTADOS: Observou-se relação linear entre volume corrente (VC e peso (r=0,640 e IMC (r=0,467. VC por peso corpóreo (ml.kg-1 mostrou-se inversamente relacionado ao IMC: IMC 30 com 7,86 ± 1,26 (p < 0,001, ANOVA. Não houve diferença entre esses grupos para a freqüência respiratória instalada. No momento dos registros, homens (n = 123 e mulheres (n = 117 apresentaram semelhantes SpO2 e P ET CO2. O IMC foi semelhante em ambos os grupos. Utilizou-se pressão positiva no final da expiração (PEEP em 78 dos procedimentos (33%. CONCLUSÕES: Estes dados descritivos permitem afirmar que os padrões de ventilação mecânica em anestesia no HCFMUSP adotam volume corrente próximo de 9 ml.kg-1, freqüência respiratória em 10 incursões por minuto. O uso de PEEP não é disseminado e, quando utilizado, está próximo de 4 cmH2O. Há correlação positiva para peso e IMC com VC. A relação entre VC por massa corpórea é inversamente relacionada ao IMC.

  12. Anesthetic experimental device for small animal Aparelho de anestesia experimental para animais de pequeno porte

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    Luiz Alfredo de Magalhães Vivas

    2007-06-01

    Full Text Available PURPOSE: The difficulty to anesthetize small laboratory animals with vaporizer prompted us to go in search of new materials, and create new techniques. The improved equipment of anesthesia we looked for should be low cost, practical, versatile, and its management serve ethical, teaching, and research purposes. METHODS: The new components of the equipment were: the vaporizer, the unidirectional valve, the glass cylinder filled with water, the flow guidance y-shape tube, the flow regulators, the mask modifications, and another free airway for emergency occurrence. A test was done with 30 Wistar rats, Rattus norvegicus albinus, divided into three groups with 10 rats for each one. Groups 1, 2 and 3 were anesthetized with Ether, Halothane and Sevoflurane respectively, using the new gadget. The anesthetic induction time, the breathing rhythm alteration during an anesthesia pre-established time (10 minutes, and the recovery time were observed. RESULTS: The equipment enabled an easy handling, and fulfilled a larger safeness and stability during the induction and anesthetic management. The test showed it was possible to make use of several anesthetic agents. CONCLUSION: The device is effective, and turns the anesthesia procedure into a very easy practice with low-cost. It should be recommended for experimental surgery, teaching and research.OBJETIVOS: As dificuldades evidenciadas no uso de vaporizadores para anestesia em animais de pequeno porte motivaram o aperfeiçoamento e a criação de novos componentes técnicos visando a construção de um aparelho de anestesia de baixo custo, prático e versátil no manuseio e que atenda aos preceitos éticos do ensino e da pesquisa. MÉTODOS: Utilizaram-se 30 ratos da linhagem Wistar, Rattus norvegicus albinus, distribuídos em três grupos. Grupo 1,2 e 3 (n=10, cada, compreenderam o uso do novo aparelho aduzido, respectivamente, do Éter; Halotano e Sevoflurano. Foram verificados o tempo de indução anest

  13. Intracortical chondroblastoma mimicking intra-articular osteoid osteoma

    Energy Technology Data Exchange (ETDEWEB)

    Ishida, Tsuyoshi; Mukai, Kiyoshi [First Department of Pathology, Tokyo Medical University, Shinjuku 6-1-1, Shinjuku-ku, Tokyo 160-8402 (Japan); Goto, Takahiro [Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo (Japan); Motoi, Noriko [Department of Pathology, Toranomon Hospital, Tokyo (Japan)

    2002-10-01

    We report a case of intra-articular intracortical chondroblastoma of the femoral condyle which radiologically appeared to be osteoid osteoma. A 19-year-old woman presented with a 3-year history of gradually increasing pain in the right knee and had been on nonsteroidal anti-inflammatory drugs for pain relief. Laboratory data were within normal limits. Radiographs showed a well-demarcated lucent lesion in the medial condyle of the right femur. A nidus-like lesion with calcifications and a sclerotic rim located in the cortex was imaged by computed tomography scan. Magnetic resonance imaging revealed bone marrow edema and soft tissue swelling around the lesion, with low signal intensity of the nidus-like lesion on both T1- and T2-weighted images. The lesion was excised en bloc and the histological diagnosis of chondroblastoma was made. A mild inflammatory reaction was observed in the bone marrow and synovium around the tumor. The chondroblastoma cells were shown to express cyclooxygenase-2 with immunohistochemistry. (orig.)

  14. Early Intra-Articular Complement Activation in Ankle Fractures

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    Hagen Schmal

    2014-01-01

    Full Text Available Cytokine regulation possibly influences long term outcome following ankle fractures, but little is known about synovial fracture biochemistry. Eight patients with an ankle dislocation fracture were included in a prospective case series and matched with patients suffering from grade 2 osteochondritis dissecans (OCD of the ankle. All fractures needed external fixation during which joint effusions were collected. Fluid analysis was done by ELISA measuring aggrecan, bFGF, IL-1β, IGF-1, and the complement components C3a, C5a, and C5b-9. The time periods between occurrence of fracture and collection of effusion were only significantly associated with synovial aggrecan and C5b-9 levels (P<0.001. Furthermore, synovial expressions of both proteins correlated with each other (P<0.001. Although IL-1β expression was relatively low, intra-articular levels correlated with C5a (P<0.01 and serological C-reactive protein concentrations 2 days after surgery (P<0.05. Joint effusions were initially dominated by neutrophils, but the portion of monocytes constantly increased reaching 50% at day 6 after fracture (P<0.02. Whereas aggrecan and IL-1β concentrations were not different in fracture and OCD patients, bFGF, IGF-1, and all complement components were significantly higher concentrated in ankle joints with fractures (P<0.01. Complement activation and inflammatory cell infiltration characterize the joint biology following acute ankle fractures.

  15. Distance between parapatellar portal and intra-articular space for needle positioning in knee osteoarthritis

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    John Butarbutar

    2013-05-01

    Full Text Available Background: Intra-articular injection is a common therapeutic procedure in osteoarthritis (OA that need high accuracy. This study was aimed to measure the distance between parapatellar skin and intra-articular space as a guidance to choose the length of needle needed to perform intra-articular injection. Methods: Twenty one knees MRI were taken from 16 females with knee osteoarthritis. The length of the needle needed to reach intra-articular space was reconstructed by drawing straight line from skin to intra-articular fluid. Paired t-test was using to analyze the mean difference of measurement of left side compare with right side with significant indicator if p-value < 0.05. Results: The entry point on both medial and lateral parapatellar were more cranial than transverse mid-patellar line. On medial portal, the closest distance from skin to intra-articular space is 27.81 ± 7.58 mm. Mean point of entry is 4.46 ± 2.16 mm cranial to mid-patellar line, and 14.20 ± 4.45 mm posterior to the prominence of medial border of patella. On lateral portal, the closest distance from skin to intra-articular space is 16.84 ± 6.79 mm. Mean point of entry is 11.10 ± 5.94 mm cranial to mid-patellar line, and 8.91 ± 3.83 mm posterior to the prominence of lateral border of patella. Conclusion: MRI knee osteoarthritis study showed that the mean distance between skin and intra-articular joint space of medial portal is 27.81 ± 7.58 mm, and lateral portal is 16.84 ± 6.79 mm. The portals on both sides is cranial to midpoint of patella, lateral appears more proximal than medial. This should be put into consideration in choosing needle length and portal projection to increase intra-articular injection accuracy. (Med J Indones. 2013;22:83-7Keywords: Needle length, osteoarthritis, parapatellar skin portal

  16. Influência da anestesia venosa total, entropia e laparoscopia sobre o estresse oxidativo

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    Rogean Rodrigues Nunes

    2012-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Estudos recentes correlacionam mortalidade pós-operatória e anestésica, especialmente a profundidade anestésica e pressão arterial sistólica (PAS. O objetivo deste estudo foi avaliar os efeitos da profundidade da anestesia venosa total (AVT realizada com remifentanil e propofol com monitoração da entropia de resposta (RE sobre as concentrações sanguíneas dos marcadores do estresse oxidativo: TBARS e glutationa, durante operações pelo acesso vídeolaparoscópico. MÉTODO: Vinte pacientes adultas, ASA I, IMC 20-26 kg.m-2, idades entre 20 e 40 anos, foram aleatoriamente distribuidas em dois grupos iguais: Grupo I - submetidas a procedimento anestésico-cirúrgico com RE mantida entre 45 e 59 e Grupo II - submetidas a procedimento anestésico-cirúrgico com RE entre 30 e 44. Em ambos os grupos, a infusão de remifentanil e propofol foi controlada pelo sitio efetor (Se, ajustados para manter RE nos valores desejados (Grupos I e II e avaliando-se sempre a taxa de supressão (TS. As pacientes foram avaliadas em seis momentos: M1(imediatamente antes da indução anestésica, M2 (antes da intubação traqueal [IT], M3 (5 minutos após IT, M4 (imediatamente antes do pneumoperitônio-PPT, M5 (1 minuto após o PPT e M6 (uma hora após a operação. Em todos os momentos foram avaliados os seguintes parâmetros: PAS, PAD, FC, RE, TS, TBARS e glutationa. RESULTADOS: Observaram-se aumentos no TBARS e glutationa em M5, tanto no Grupo I como no Grupo II (p GI em M5 - p < 0,05% sugerem interferência de mais um fator (anestesia profunda, como responsável pelo aumento no MA, provavelmente como resultados de maior depressão do sistema nervoso autônomo e menor autorregulação esplâncnica.

  17. O butorfanol na anestesia pela romifidina-tiletamina-zolazepam em gatos

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    Selmi André Luis

    2003-01-01

    Full Text Available Visando observar os efeitos do butorfanol (B na anestesia produzida pela associação de romifidina (R e tiletamina-zolazepam (TZ, foram utilizados seis gatos adultos, de forma que todos animais receberam a associação de romifidina-tiletamina-zolazepam (grupo RTZ ou a associação de romifidina-tiletamina-zolazepam-butorfanol (grupo RTZB. Os animais receberam em aplicação única, por via intramuscular, 7mg.kg-1 de tiletamina e 7mg.kg-1 de zolazepam e 40µg.kg-1 de romifidina (grupo RTZ ou a mesma associação acrescida de 0,2mg.kg-1 de B (grupo RTZB. A freqüência cardíaca, freqüência respiratória, pressão arterial sistólica, diastólica e média por método não-invasivo oscilométrico, saturação de oxihemoglobina e temperatura retal foram avaliadas durante 120 minutos e comparadas aos valores basais. Os efeitos anestésicos foram caracterizados por meio de um sistema de escores. Outros dados como período de latência, período anestésico hábil e período de recuperação foram mensurados para efeito comparativo. Os períodos de latência e anestésico hábil foram significativamente mais prolongados no grupo RTZB. Ocorreu diminuição da freqüência respiratória no grupo RTZB, havendo decréscimo transitório no grupo RTZ. A freqüência cardíaca não variou no grupo RTZ até os 60 minutos e decresceu significativamente no grupo RTZB. Conclui-se que a associação RTZ produz anestesia com mínimos efeitos cardiovasculares e que a adição do butorfanol à associação prolonga o tempo anestésico hábil, além de proporcionar analgesia mais duradoura, mas provoca efeitos colaterais como decréscimo da freqüência cardíaca e da freqüência respiratória em gatos.

  18. Reduction of intraarticular adhesion by topical application of colchicine following knee surgery in rabbits

    Science.gov (United States)

    Sun, Yu; Liang, Yuan; Hu, Jinlong; Wang, Jingcheng; Wang, Daxin; Li, Xiaolei; Yan, Lianqi

    2014-01-01

    The aim of this study was to investigate the efficacy of topical application of colchicine in reducing intraarticular adhesion in rabbits. Thirty-six rabbits were randomly and equally divided into three groups. An approximately 10 × 10 mm2 area of cortical bone was removed from both sides of the left femoral condyle, and the cancellous bone underneath was exposed. Cotton pads soaked with different concentrations of colchicine or saline were applied to the decorticated areas for 10 minutes. The surgical limb was fixed in a flexed position for 4 weeks postoperatively. To evaluate knee intraarticular adhesion, we performed macroscopic evaluation, histological and collagen density analyses, hydroxyproline content determination, fibroblast counting and densitometric analyses. The results showed that loose collagen tissues with little or no adhesion were present around the decorticated areas in the group treated with 0.5 mg/ml colchicine. The intraarticular adhesion score, hydroxyproline content, number of fibroblasts and densitometric value in this group were also significantly lower than those in the other groups. There was moderate intraarticular adhesion in the group treated with 0.1 mg/ml colchicine. However, dense scar tissue with dense adhesions was found in the control group. In conclusion, topical application of 0.5 mg/ml colchicine may reduce knee intraarticular adhesion. PMID:25245566

  19. Intraarticular Pulsed Radiofrequency to Treat Refractory Lumbar Facet Joint Pain in Patients with Low Back Pain.

    Science.gov (United States)

    Chang, Min Cheol; Cho, Yun-Woo; Ahn, Da Hyun; Do, Kyung Hee

    2018-01-06

    Many treatment techniques have been used for refractory lumbar facet joint pain; however, their efficacy has been controversial. In this study, we investigated the clinical efficacy and safety of intra-articular pulsed radiofrequency for the treatment of refractory lumbar facet joint pain in patients with low back pain. Twenty patients with refractory lumbar facet joint pain were recruited, and each patient was treated via intra-articular pulsed radiofrequency. The treatment effects were measured with a numerical rating scale, and the technical accuracy of intra-articular pulsed radiofrequency treatment was evaluated independently by 2 radiologists. Any adverse events or complications also were checked. We performed intra-articular pulsed radiofrequency treatment at 48 levels of the lumbar facet joints in 20 patients (5 men and 15 women; mean age, 64.50 ± 10.65 years) with refractory lumbar facet joint pain. Pain scores were significantly reduced at 1 month, 3 months, and 6 months after treatment (P radiofrequency results in all 20 patients, without any serious adverse effects. Treatment using intra-articular pulsed radiofrequency is an alternative to other techniques in patients with refractory lumbar facet joint pain. Copyright © 2018 Elsevier Inc. All rights reserved.

  20. Clinicopathologic findings following intra-articular injection of autologous and allogeneic placentally derived equine mesenchymal stem cells in horses.

    Science.gov (United States)

    Carrade, Danielle D; Owens, Sean D; Galuppo, Larry D; Vidal, Martin A; Ferraro, Gregory L; Librach, Fred; Buerchler, Sabine; Friedman, Michael S; Walker, Naomi J; Borjesson, Dori L

    2011-04-01

    The development of an allogeneic mesenchymal stem cell (MSC) product to treat equine disorders would be useful; however, there are limited in vivo safety data for horses. We hypothesized that the injection of self (autologous) and non-self (related allogeneic or allogeneic) MSC would not elicit significant alterations in physical examination, gait or synovial fluid parameters when injected into the joints of healthy horses. Sixteen healthy horses were used in this study. Group 1 consisted of foals (n = 6), group 2 consisted of their dams (n = 5) and group 3 consisted of half-siblings (n = 5) to group 1 foals. Prior to injection, MSC were phenotyped. Placentally derived MSC were injected into contralateral joints and MSC diluent was injected into a separate joint (control). An examination, including lameness evaluation and synovial fluid analysis, was performed at 0, 24, 48 and 72 h post-injection. MSC were major histocompatibility complex (MHC) I positive, MHC II negative and CD86 negative. Injection of allogeneic MSC did not elicit a systemic response. Local responses such as joint swelling or lameness were minimal and variable. Intra-articular MSC injection elicited marked inflammation within the synovial fluid (as measured by nucleated cell count, neutrophil number and total protein concentration). However, there were no significant differences between the degree and type of inflammation elicited by self and non-self-MSC. The healthy equine joint responds similarly to a single intra-articular injection of autologous and allogeneic MSC. This pre-clinical safety study is an important first step in the development of equine allogeneic stem cell therapies.

  1. Intra-articular injection with triamcinolone hexacetonide in patients with rheumatoid arthritis: prospective assessment of goniometry and joint inflammation parameters

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    Rita Nely Vilar Furtado

    Full Text Available Abstract Objectives: To evaluate local joint variables after intra-articular injection with triamcinolone hexacetonide in rheumatoid arthritis patients. Methods: We blindly and prospectively (baseline, 1, 4, 12 and 24 weeks evaluated metacarpophalangeal, wrist, elbow, shoulder, knee and ankle joints after triamcinolone hexacetonide intra-articular injection by the following outcome measures: visual analogue scale 0–10 cm (VAS for rest pain (VASR; VAS for movement pain (VASM; VAS for joint swelling (VASSw; flexion (FlexG and extension (ExtG. Results: 289 patients (635 joints were studied. VASSw (p < 0.001 and VASR (0.001 < p < 0.016 improved from T0 to T4, T12 and T24 for all joints. VASM improved from T0 to T4 (p < 0.021 for all joints; T0 to T12 (p < 0.023 for MCF and knee; T0 to T24 (p < 0.019 only for MCF and knee. FlexG improved from T0 to T4 (p < 0.001 for all joints; T0 to T12 (p < 0.001 and T0 to T24 (p < 0.02 only for MCF and knee. ExtG improved from T0 to T4 (p < 0.001 for all joints except for elbow; T0 to T12 (p = 0.003 for wrist, metacarpophalangeal and knee; and T0 to T24 (p = 0.014 for MCF and knee. Conclusion: VASSw responded better at short and medium term after IAI with triamcinolone hexacetonide in our sample of RA patients.

  2. Intra-articular injection with triamcinolone hexacetonide in patients with rheumatoid arthritis: prospective assessment of goniometry and joint inflammation parameters.

    Science.gov (United States)

    Furtado, Rita Nely Vilar; Machado, Flávia Soares; Luz, Karine Rodrigues da; Santos, Marla Francisca Dos; Konai, Monique Sayuri; Lopes, Roberta Vilela; Natour, Jamil

    To evaluate local joint variables after intra-articular injection with triamcinolone hexacetonide in rheumatoid arthritis patients. We blindly and prospectively (baseline, 1, 4, 12 and 24 weeks) evaluated metacarpophalangeal, wrist, elbow, shoulder, knee and ankle joints after triamcinolone hexacetonide intra-articular injection by the following outcome measures: visual analogue scale 0-10cm (VAS) for rest pain (VASR); VAS for movement pain (VASM); VAS for joint swelling (VASSw); flexion (FlexG) and extension (ExtG). 289 patients (635 joints) were studied. VASSw (p<0.001) and VASR (0.001

  3. Avaliação da memória sob anestesia venosa total Evaluación de la memoria bajo anestesia venosa total The assessment of memory under total intravenous anesthesia

    Directory of Open Access Journals (Sweden)

    Gulistan Aktas

    2013-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Neste estudo, objetivamos avaliar a memória implícita e explícita em pacientes submetidos à cirurgia abdominal sob anestesia venosa total (AVT com propofol e remifentanil, na qual o nível de anestesia foi controlado pelo monitoramento do índice bispectral (BIS. MÉTODO: Anestesia venosa total foi administrada a 60 pacientes adultos para obter níveis de BIS de 40-60. Os pacientes foram randomicamente divididos em três grupos, de acordo com as gravações que ouviram. Os pacientes do grupo categoria (CT ouviram uma fita gravada contendo cinco nomes de animais. Os pacientes do grupo recordar palavras (RP ouviram uma fita gravada contendo cinco palavras de frequência média na língua turca, depois de adaptadas. Os pacientes do grupo controle (GC ouviram os sons do mar até o fim da cirurgia. Duas horas após a cirurgia, os testes foram administrados a cada paciente na sala de recuperação para avaliar a memória. RESULTADOS: Houve uma diferença entre os escores dos grupos CT e GC no Miniexame do Estado Mental (MMSE; todos os escores foram > 20. Os resultados dos testes de categoria e recordar palavras, aplicados para avaliar a memória implícita, não foram estatisticamente diferentes entre os grupos. Não houve evidência de memória implícita em nenhum dos pacientes. Um paciente lembrou-se de ouvir "o som de água" como uma prova de memória explícita. Onze pacientes declararam não ter sonhado. CONCLUSÕES: Apesar de não termos encontrado nenhuma evidência de memória implícita sob anestesia adequada com AVT, um paciente apresentou memória explícita. Embora a profundidade adequada da anestesia fornecida pelo monitoramento do BIS corrobore nossos resultados para a memória implícita, ela não explica os resultados para a memória explícita.JUSTIFICATIVA Y OBJETIVOS: En este estudio evaluamos la memoria implícita y explícita en pacientes sometidos a la cirugía abdominal bajo anestesia venosa total

  4. Combined intra-articular glucocorticoid, bupivacaine and morphine reduces pain and convalescence after diagnostic knee arthroscopy

    DEFF Research Database (Denmark)

    Rasmussen, Sten; Lorentzen, Jan S; Larsen, Allan S

    2002-01-01

    We studied the effect of intra-articullar saline vs. bupivacaine + morphine or bupivacaine morphine + methylprednisolone after diagnostic knee arthroscopy. In a double-blind randomized study, 60 patients undergoing diagnostic knee arthroscopy without a therapeutic procedure were allocated to groups...... receiving intra-articular saline, intra-articular bupivacaine 150 mg + morphine 4 mg or the same dose of bupivacaine + morphine + intra-articular methylprednisolone 40 mg at the end of arthroscopy during general anesthesia. All patients were instructed to resume normal activities immediately after...... the procedure. Pain during movement and walking, leg muscle force and joint effusion, use of crutches and duration of sick leave were assessed. A combination of bupivacaine and morphine reduced pain, duration of immobilization and of convalescence. The addition of methylprednisolone further reduced pain, use...

  5. Intra-Articular Giant Heterotopic Ossification following Total Knee Arthroplasty for Charcot Arthropathy

    Directory of Open Access Journals (Sweden)

    Arata Nakajima

    2013-01-01

    Full Text Available Although the Charcot arthropathy may be associated with serious complications, total knee arthroplasty (TKA is the preferred choice of treatment by patients. This case report presents an 80-year-old man with intra-articular giant heterotopic ossification following loosening of femoral and tibial implants and femoral condylar fracture. He had undergone TKA because of Charcot neuropathy seven years ago and had been doing well since. Immediately after a left knee sprain, he became unable to walk. Because he had developed a skin ulcer on his left calf where methicillin-resistant Staphylococcus aureus was detected, we postponed revision surgery until the ulcer was completely healed. While waiting, intra-articular bony fragments grew larger and formed giant heterotopic ossified masses. Eventually, the patient underwent revision surgery, and two major ossified masses were carefully and successfully extirpated. It should be noted that intra-articular heterotopic giant ossification is a significant complication after TKA for neuropathic arthropathy.

  6. Intra-articular Nodular Fasciitis: An Unexpected Diagnosis for a Joint Lesion: A Case Report

    Directory of Open Access Journals (Sweden)

    MF Michelle Chan

    2014-07-01

    Full Text Available Pathological lesions in and around a joint can arise from underlying dermis, subcutis, deep muscle, bone or synovium. Clinical presentation can include joint pain, joint swelling, palpable masses and mechanical restriction. Whilst giant cell tumour of tendon sheath, pigmented villonodular synovitis, synovial chondromatosis, lipoma arborescens, juxta articular myxomas and inflammatory arthritis are the better-known conditions of the joint. Intra-articular nodular fasciitis, on the other hand, is less well recognized both clinically and radiologically. It is rarely seen in routine practice and is only described in case reports in the literature. Due to the non-specific clinical and radiological findings as well as the unfamiliarity with the entity, the diagnosis of intra-articular nodular fasciitis is usually clinched only after histological examination. We present a case of intra-articular nodular fasciitis arising in the knee joint which was not suspected clinically or radiologically.

  7. Comparison of analgesic effects of intra-articular tenoxicam and morphine in anterior cruciate ligament reconstruction.

    Science.gov (United States)

    Guler, Gulen; Karaoglu, Sinan; Velibasoglu, Hediye; Ramazanogullari, Nesrin; Boyaci, Adem

    2002-07-01

    This study compared the analgesic effect of intra-articular injection of tenoxicam with that of morphine on postoperative pain after anterior cruciate ligament (ACL) reconstruction. Forty-two patients undergoing arthroscopically ACL reconstructions using hamstring tendons underwent the same anesthetic protocol. The patients were randomized to receive 25 ml normal saline, 20 mg tenoxicam in 25 ml normal saline, or 2 mg morphine in 25 ml normal saline. Postoperative pain was assessed using a visual analogue scale and measuring analgesic requirements. We found both that both intra-articular tenoxicam and intra-articular morphine provided better analgesia than that in the control group. Although pain scores were similar between tenoxicam and morphine groups 30 min postoperative, the analgesic requirements in with tenoxicam were significantly lower than those with morphine group 3-6 h postoperatively.

  8. Usefulness of fluoroscopy-guided intra-articular injection of the knee

    Energy Technology Data Exchange (ETDEWEB)

    Myung, Jae Sung; Lee, Joon Woo [Seoul National University Bundang Hospital, Seongnam (Korea, Republic of); Lee, Ji Yeon [Kangwon National University College of Medicine, Chuncheon (Korea, Republic of)] (and others)

    2007-06-15

    To determine the accuracy of the intra-articular location of hyaluronic acid injection using a blind approach and to establish the usefulness of fluoroscopy-guided intra-articular injection. A fluoroscopy unit was used for 368 intra-articular injections of hyaluronic acid to 93 knees in 65 patients. Initially, blind needle positioning was conducted on the fluoroscopy table. The failure rate of the blind approach among the 368 injections was evaluated, and a relationship between the Kellgren-Lawrence grade (K-L grade) and the incidence of repeated failures using the blind approach was determined for injections to 52 knees in 37 patients who received a complete cycle of injections (five consecutive injections with a one-week interval between injections). Using a blind approach, 298 of 368 trials (81.2%) resulted in a needle tip being placed in an intra-articular location, while 70 of 368 trials resulted in an extra-articular placement of the needle tip. Among 52 knees to which a complete cycle of injection (five consecutive injections with a one-week interval between injections) was administered, repeated failure of intra-articular placement using the blind approach was seen for 18 knees (34.6%); a more severe K-L grade assigned was associated with a higher rate of repeated failure. However, the trend was not statistically significant based on the Chi-squared test ({rho} value = 0.14). Fluoroscopy-guided needle placement may be helpful to ensure therapeutic intra-articular injection of the knee.

  9. Usefulness of fluoroscopy-guided intra-articular injection of the knee

    International Nuclear Information System (INIS)

    Myung, Jae Sung; Lee, Joon Woo; Lee, Ji Yeon

    2007-01-01

    To determine the accuracy of the intra-articular location of hyaluronic acid injection using a blind approach and to establish the usefulness of fluoroscopy-guided intra-articular injection. A fluoroscopy unit was used for 368 intra-articular injections of hyaluronic acid to 93 knees in 65 patients. Initially, blind needle positioning was conducted on the fluoroscopy table. The failure rate of the blind approach among the 368 injections was evaluated, and a relationship between the Kellgren-Lawrence grade (K-L grade) and the incidence of repeated failures using the blind approach was determined for injections to 52 knees in 37 patients who received a complete cycle of injections (five consecutive injections with a one-week interval between injections). Using a blind approach, 298 of 368 trials (81.2%) resulted in a needle tip being placed in an intra-articular location, while 70 of 368 trials resulted in an extra-articular placement of the needle tip. Among 52 knees to which a complete cycle of injection (five consecutive injections with a one-week interval between injections) was administered, repeated failure of intra-articular placement using the blind approach was seen for 18 knees (34.6%); a more severe K-L grade assigned was associated with a higher rate of repeated failure. However, the trend was not statistically significant based on the Chi-squared test (ρ value = 0.14). Fluoroscopy-guided needle placement may be helpful to ensure therapeutic intra-articular injection of the knee

  10. Is intra-articular magnesium effective for postoperative analgesia in arthroscopic shoulder surgery?

    Science.gov (United States)

    Saritas, Tuba Berra; Borazan, Hale; Okesli, Selmin; Yel, Mustafa; Otelcioglu, Şeref

    2015-01-01

    Various medications are used intra-articularly for postoperative pain reduction after arthroscopic shoulder surgery. Magnesium, a N-methyl-D-aspartate receptor antagonist, may be effective for reduction of both postoperative pain scores and analgesic requirements. A total of 67 patients undergoing arthroscopic shoulder surgery were divided randomly into two groups to receive intra-articular injections of either 10 mL magnesium sulphate (100 mg⁄mL; group M, n=34) or 10 mL of normal saline (group C, n=33). The analgesic effect was estimated using a visual analogue scale 1 h, 2 h, 6 h, 8 h, 12 h, 18 h and 24 h after operation. Postoperative analgesia was maintained by intra-articular morphine (0.01%, 10 mg) + bupivacaine (0.5%, 100 mL) patient-controlled analgesia device as a 1 mL infusion with a 1 mL bolus dose and 15 min lock-out time; for visual analogue scale scores >5, intramuscular diclofenac sodium 75 mg was administered as needed during the study period (maximum two times). Intra-articular magnesium resulted in a significant reduction in pain scores in group M compared with group C 1 h, 2 h, 6 h, 8 h and 12 h after the end of surgery, respectively, at rest and with passive motion. Total diclofenac consumption and intra-articular morphine + bupivacaine consumption were significantly lower in group M. Postoperative serum magnesium levels were significantly higher in group M, but were within the normal range. Magnesium causes a reduction in postoperative pain in comparison to saline when administered intra-articularly after arthroscopic shoulder surgery, and has no serious side effects.

  11. Application of CT in assessment of displaced intraarticular calcaneal fractures

    International Nuclear Information System (INIS)

    Wang Zhijie; Liu Jihua; Zhong Shizhen; Ding Zihai

    2007-01-01

    Objective: To evaluate the significance of CT assessment for extraarticular anatomy in treatment of displaced intraarticular calcaneal fractures. Methods: (1) Measurement of normal calcaneum 40 pieces of adult calcaneum specimen were measured, items of measurement included height of culmination of posterior facet and tuberosity, width of posterior edge of sustentaculum and tuberosity. (2) CT measurement of calcaneum. Transverse (axial) and coronal CT scanning were obtained from 20 feet with displaced intraarticular calcaneal and 20 normal feet as control. Following items were measured in CT scanning: the height of culmination of posterior facet and tuberosity, the coronal talocalcaneal angle, in coronal scanning, the width of posterior edge of sustentaculum and tuberosity, the axial calcaneocuboid angle, in axial scanning. Results: (1) Measurement of height of calcaneum height of culmination of posterior facet and tuberosity of calcaneal specimen were (43.07 ± 2.85) mm and (44.69 ± 3.67) mm respectively, and these two items from CT scanning of normal feet were (42.84 ± 1.66) mm, (43.40 ± 3.01)mm, and from CT scanning of feet with calcaneal fractures were (34.76 ± 3.24 )mm, (40.41 ± 3.69) mm. There was a statistically significant different between these two items for normal calcaneal specimen and for CT scanning of feet with calcaneal fractures (P<0.001), and between CT scanning of normal feet and of feet with calcaneal fractures as well. (2) Measurement of width of calcaneum width of posterior edge of sustentaculum and tuberosity were (30.53 ± 2.06) mm and (33.57 ± 2.17) mm respectively, and these two items from CT scanning of normal feet were (30.47 ± 2.33) mm, (32.69 ± 2.00) mm, and from CT scanning of feet with calcaneal fractures were (45.99 ± 4.79) mm, ( 36.28 ± 2.08) mm. There was a statistically significant different between these two items for normal calcaneal specimen and for CT scanning of feet with calcaneal fractures (P<0.001), and between

  12. Alergia a los anestésicos locales en odontoestomatología : un mito o una realidad

    OpenAIRE

    Viñals Iglesias, Helena; Berini Aytés, Leonardo; Caballero Herrera, Rafael; Sabater Recolons, Ma. del Mar

    1996-01-01

    Las reacciones adversas a los anestésicos locales son muy frecuentes, sin embargo las verdaderas sensibilizaciones frente a ellos, son casi excepcionales. A lo largo de este artículo se discute la problemática del uso odontológico de este tipo de anestesia.

  13. Exostosis-like intra-articular periosteal osteoblastoma: a rare case.

    Science.gov (United States)

    Abolghasemian, Mansour; Rezaie, Mitra; Behgoo, Abas; Shoushtarizadeh, Tina; Ghazavi, Mohammad Taghi

    2010-06-01

    Osteoblastoma is a relatively rare benign bone tumor, most often located in the vertebral column or metaphysis of the long bones, particularly the femur and the tibia. Periosteal osteoblastoma is the least common type. Exostosis-like appearance is not common even in periosteal osteoblastoma, a very rare type of this tumor. In addition, an intraarticular location is uncommon for osteoblastomas. Here we report the case of a 25-year-old man with intra-articular exostosis-like periosteal osteoblastoma of the hip that resulted in impingement and osteoarthritis.

  14. Comparative efficacy of intra-articular hyaluronic acid and corticoid injections in osteoarthritis of the first carpometacarpal joint: results of a 6-month single-masked randomized study.

    Science.gov (United States)

    Monfort, Jordi; Rotés-Sala, Delfin; Segalés, Nuria; Montañes, Francisco-Jose; Orellana, Cristobal; Llorente-Onaindia, Jone; Mojal, Sergi; Padró, Isabel; Benito, Pere

    2015-03-01

    The study aim was to compare the efficacy and safety of ultrasound-guided intra-articular injections of hyaluronic acid and betamethasone in the management of patients with osteoarthritis of the thumb. Eighty-eight evaluable patients diagnosed with osteoarthritis of the thumb (Kellgren-Lawrence grade II-III) received ultrasound-guided intra-articular treatment with hyaluronic acid (48) or betamethasone (40). In total, 3 local injections were scheduled at 7-day intervals. Assessments were performed at baseline and at 7, 14, 30, 90, and 180 days. In both study groups, the pain Visual Analogue Scale and Functional Index for Hand Osteoarthritis scores decreased significantly during follow-up compared to baseline. There were no significant differences between the groups. However, at 90 days, the functional score showed a trend towards greater clinical improvement in the hyaluronic acid group (P 0.071). A subanalysis of patients with Functional Index score≥5 and Visual Analogue Scale score≥3 at baseline showed a significantly higher median functionality score in the hyaluronic acid group (P 0.005 at 90 days and P 0.020 at 180 days). Further limiting analysis to a baseline pain score≥5 showed significantly greater improvement in functionality score (P 0.004 at 180 days), which was already apparent after the second intra-articular injection at 14 days (P 0.028). In this patient subset, the mean pain score also improved significantly at 180 days (P 0.02). Both hyaluronic acid and betamethasone were effective and well-tolerated for the management of rhizarthrosis. Hyaluronic acid was more effective over time and more efficiently improved functionality and pain in patients with more severe symptoms. Copyright © 2014 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

  15. Anestesia em paciente com síndrome de Gilbert: relato de caso Anestesia en paciente con síndrome de Gilbert: relato de caso Anesthesia in a patient with Gilbert's syndrome: case report

    Directory of Open Access Journals (Sweden)

    Fabiano Timbó Barbosa

    2004-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A síndrome de Gilbert é uma doença crônica benigna, a qual leva à icterícia recorrente com grande aumento da bilirrubina não conjugada, que pode levar à toxicidade após o uso de medicações utilizadas na prática diária. O objetivo deste relato é descrever a conduta anestésica em uma paciente com síndrome de Gilbert, submetida à cirurgia videolaparoscópica. RELATO DO CASO: Paciente do sexo feminino, com 22 anos, portadora da síndrome de Gilbert, submetida à cirurgia videolaparoscópica sob anestesia geral com propofol, alfentanil, succinilcolina, atracúrio e isoflurano. Não houve sinais de toxicidade durante a anestesia. A paciente apresentou recuperação pós-operatória sem intercorrências e recebeu alta hospitalar após três dias. CONCLUSÕES: O paciente portador da síndrome de Gilbert pode ser submetido à anestesia geral de forma segura sem o aparecimento de toxicidade desde que sejam evitados os fatores que possam levar à diminuição da atividade da glicuroniltransferase.JUSTIFICATIVA Y OBJETIVOS: La síndrome de Gilbert es una enfermedad crónica benigna la cual lleva a la ictericia recurrente con grande aumento de la bilirrubina no conjugada, que puede llevar a la toxicidad después del uso de medicamentos utilizadas en la práctica diaria. El objetivo de este relato es describir la conducta anestésica en una paciente con síndrome de Gilbert, sometida a cirugía videolaparoscópica. RELATO DEL CASO: Paciente del sexo femenino, con 22 años, portadora de la síndrome de Gilbert fue sometida a cirugía videolaparoscópica bajo anestesia general con propofol, alfentanil, succinilcolina, atracúrio e isoflurano. No hubo señales de toxicidad durante la anestesia. La paciente presentó recuperación pós-operatoria sin intercurrencias y recibió alta hospitalar después de tres días. CONCLUSIONES: El paciente portador del síndrome de Gilbert puede ser sometido a la anestesia general de

  16. An evaluation of new circle system of anesthesia. Quantitative anesthesia with isoflurane in new zealand rabbits Avaliação de um novo sistema circular de anestesia: anestesia quantitativa com isuflorane em coelhos

    Directory of Open Access Journals (Sweden)

    Neuber M. Fonseca

    1997-12-01

    Full Text Available A small circuit system of anesthesia was developed by Fonseca and Goldenberg in 1993. The authors used in this study New Zealand White (NZW rabbits under closed system anesthetic regiment by insoflurane. Twenty male adult New Zealand rabbits were distributed in two groups of ten animals. No premedicant drugs were given. Endotraqueal intubation was made after intravenous administration of propofol (10mg/kg. Insoflurane was used to anesthesia management, administred by lowflow closed system technique with cooper kettle vaporizer, fixed by pre-calculated vaporizing flow in double times intervals. The group II underwent surgical periostal scratching in the medial tibial surface at the proximal shaft. Rabbits breathed spontaneously. Hypotensio, hypercapnia and respiratory acidosis were characteristic of the cardiopulmonary effects of the anesthesia. The corneal reflex and pinch reflex was useful as reliable indicators of anesthesic depth. Manual or mechanical ventilation should be considered as a way of improving alveolar ventilation and normalize blood-gas values. The system developed by Fonseca and Goldenberg was considered suitable for anesthesic management in rabbits.Um sistema circular de anestesia para animais de pequeno porte foi desenvolvido por FONSECA e GOLDENBERG, em 1993. No presente estudo foram utilizados 20 coelhos brancos linhagem Nova Zelândia, submetidos ao sistema com isoflurane, distribuidos em dois grupos de 10 animais. O grupo I, controle, que foi apenas anestesiado e o grupo II foi submetido a raspagem periostal da parte proximal e medial da tíbia. Não foi administrada droga pré-anestésica. Após administração do propofol intravenoso (10mg/kg procedeu-se a intubação endotraqueal. O isuflorane foi administrado lentamente no sistema circular de anestesia. Os animais respiravam espontaneamente. Houve efeitos cardiorespiratórios conseqüentes da anestesia, tais como, hipotensão, hipercapnia e acidose respiratória. O

  17. The effectiveness of 2 consecutive intra-articular polydeoxyribonucleotide injections compared with intra-articular triamcinolone for hemiplegic shoulder pain: A STROBE-complaint retrospective study.

    Science.gov (United States)

    Park, Donghwi; Yu, Kwang Jae; Cho, Ju Young; Woo, Seung Beom; Park, Junu; Lee, Zeeihn; Kim, Jong Min

    2017-11-01

    The aim of this study was to investigate the effects of intra-articular injection of polydeoxyribonucleotide (PDRN), compared with intraarticular triamcinolone (TA) injection, in subacute stroke patients with hemiplegic shoulder pain (HSP).Participants were subacute stroke patients with HSP who had undergone 2 consecutive intra-articular injections of TA or PDRN.Numeric rating scale (NRS) and passive range of motion (PROM) of hemiplegic shoulder were evaluated until 4 weeks after 2nd injection.In the results, there were significant improvements in all PROM measures 2 weeks after the second injection, compared with pre-injection results, in both groups (P < .05). In the PDRN group, however, none of the PROM measures were significantly improved at 3 and 4 weeks after the second injection, compared with pre-injection results (P ≥ .05). When comparing pre-injection results with those at 4 weeks after the second injection, all PROM and NRS measures in the TA group were more improved than in the PDRN group, but this was not statistically significant (P ≥ .05).In conclusion, considering the systemic side effects of steroids, especially among patients with diabetes or metabolic syndrome, PDRN seems to be a worthwhile treatment option for HSP, although PDRN does not seem to have an equivalent persistence effects when compared with TA.

  18. Anestesia regional para cirugía cardiovascular pediátrica

    Directory of Open Access Journals (Sweden)

    Lincoln de la Parte Pérez

    2004-03-01

    Full Text Available Durante los últimos años se han publicado numerosos artículos sobre el uso de anestesia espinal y peridural asociada a la anestesia general, en niños sometidos a operaciones cardiovasculares. El uso de esta técnica produce una disminución significativa de la respuesta de estrés que se observa durante y después de las operaciones cardiovasculares y que es particularmente intensa en recién nacidos y lactantes. Adicionalmente produce una mejor función pulmonar, mayor estabilidad hemodinámica, posibilidad de extubación precoz, excelente analgesia posoperatoria y una menor estadía en la sala de recuperación anestésica. Las complicaciones más importantes asociadas a su uso son la hipotensión arterial, la depresión respiratoria y el hematoma epidural. Las contraindicaciones más importantes para la realización de estas técnicas incluyen la presencia de cianosis, policitemia, coagulopatía preexistente y en los lactantes menores de 6 meses. Existe además un dilema ético importante relacionado con su uso. Por una parte es cierto que pueden obtenerse un grupo de ventajas, que también podrían lograrse con la aplicación de otras técnicas encaminadas a la extubación precoz (Fast track cardiac anesthesia y por la otra, existe siempre el peligro latente de sangramiento y de formación de un hematoma epidural. Se realiza una revisión bibliográfica sobre las diferentes técnicas utilizadas.Several articles have been published on the use of spinal and epidural anesthesia associated with general anesthesia in children undergoing cardiovascular surgery. The use of this technique causes a significant decrease of the stress response observed during and after cardiovascular surgery and that is particularly intense in newborns and infants. Besides, it produces a better pulmonary function, a longer hemodynamic stability, the possibility of fast track cardiac anesthesia, an excellent postoperative analgesia and a shorter stay in the

  19. Doença de Moyamoya e anestesia com sevoflurano fora do centro cirúrgico: relato de caso

    OpenAIRE

    Machado, Sheila Braga; Mendes, Florentino Fernandes; Angelini, Adriana de Campos

    2002-01-01

    JUSTIFICATIVA E OBJETIVOS: A doença de Moyamoya é uma desordem cerebrovascular progressiva que representa um desafio anestésico em virtude da precária circulação cerebral destes pacientes, constituindo-se numa importante causa de acidente vascular cerebral em indivíduos jovens. O objetivo deste relato é apresentar o caso de um paciente com doença de Moyamoya que foi submetido à anestesia geral com sevoflurano para procedimento diagnóstico fora do centro cirúrgico. RELATO DO CASO: Criança com ...

  20. Anestesia para paciente portadora de múltiplas afecções endócrinas: relato de caso

    OpenAIRE

    Maciel, Renato Toledo; Fernandes, Fátima Carneiro; Pereira, Leonel dos Santos

    2008-01-01

    JUSTIFICATIVA E OBJETIVOS: O insulinoma é o tumor endócrino pancreático mais comum. Pode estar associado a neoplasias endócrinas múltiplas (NEM). Relatou-se o caso de paciente com distúrbios endócrinos múltiplos que, no entanto, não se enquadram em síndromes (NEM) já conhecidas e com particularidades clínico-anestésicas que influenciaram no manuseio de sua anestesia. RELATO DO CASO: Paciente feminina, 23 anos, apresentando hipoglicemias de difícil controle associadas à doença de Cushing e pro...

  1. Anestesia para septoplastia e turbinectomia em paciente portador de doença de von Willebrand: relato de caso

    OpenAIRE

    Abreu, Múcio Paranhos de; Porto, André de Moraes; Minari, Alexandre Leite; Caseli, Henrique Gonçalves

    2003-01-01

    JUSTIFICATIVA E OBJETIVOS: Embora a doença de von Willebrand seja o mais comum dos distúrbios hemorrágicos hereditários, as publicações nacionais, relacionando esta doença e a prática anestésica, são escassas. O objetivo deste relato é apresentar um caso de anestesia geral para septoplastia e turbinectomia em paciente portador de doença de von Willebrand - Tipo I, tratado profilaticamente com desmopressina (1-deamino-8-D-arginina vasopressina, DDAVP) nos períodos pré e pós-operatório. RELATO ...

  2. SINERGISMO FARMACODINÁMICO. A PROPÓSITO DE UN CASO INTERVENIDO QUIRÚRGICAMENTE DE URGENCIA BAJO ANESTESIA GENERAL.

    OpenAIRE

    Yesid Pallares Villarreal; Marcia Triana Falcon; Eustolgio Calzado Marten; Marta Sofia López Rodríguez

    2004-01-01

    Presentamos una paciente femenina geriatrica con antecedentes de hipertensiòn arterial y trastornos psiquiatricos intervenida quirurgicamente de urgencia por un cuadro doloroso abdominal, con una interaccion farmacodinamica por sinergismo del doxepin y captopril potenciada por los efectos de la anestesia general. La hipotensiòn arterial fue la forma clínica de presentación. La paciente se recibió hipotensa por la administración preoperatoria de doxepin tratamiento de base y de captopril trata...

  3. O butorfanol na anestesia pela romifidina-tiletamina-zolazepam em gatos Butorphanol in romifidine-tiletamine-zolazepam anesthesia in cats

    OpenAIRE

    André Luis Selmi; Glenda Ramalho Barbudo-Selmi; Guilherme Maia Mendes; Concepta McManus; Christine Souza Martins

    2003-01-01

    Visando observar os efeitos do butorfanol (B) na anestesia produzida pela associação de romifidina (R) e tiletamina-zolazepam (TZ), foram utilizados seis gatos adultos, de forma que todos animais receberam a associação de romifidina-tiletamina-zolazepam (grupo RTZ) ou a associação de romifidina-tiletamina-zolazepam-butorfanol (grupo RTZB). Os animais receberam em aplicação única, por via intramuscular, 7mg.kg-1 de tiletamina e 7mg.kg-1 de zolazepam e 40µg.kg-1 de romifidina (grupo RTZ) ou a m...

  4. Procedimiento alternativo para premedicación y anestesia de primates (no humanos). Uso de ketamina y halotano

    OpenAIRE

    Arcila Quiceno, Victor Hernan; Reyes, Hector; Reyes, Jorge; Sanchez, Favio

    2005-01-01

    La presencia frecuente de fauna silvestre en los centros de atención médico-veterinaria generan la necesidad de conocer o establecer protocolos farmacológicos acordes con la especie; la literatura en estos tópicos es limitada o escasa, lo que lleva a que el médico veterinario plantee de forma empírica o basado en su experiencia el uso de varios medicamentos. Los protocolos de anestesia requieren un manejo preciso para evitar un efecto marcado sobre el sistema nervioso. Se recibió un paciente ...

  5. Intra-articular hyaluronate, tenoxicam and vitamin E in a rat model of osteoarthritis: evaluation and comparison of chondroprotective efficacy.

    Science.gov (United States)

    Ozkan, Feyza Unlu; Uzer, Gokcer; Türkmen, Ismail; Yildiz, Yavuz; Senol, Serkan; Ozkan, Korhan; Turkmensoy, Fatih; Ramadan, Saime; Aktas, Ilknur

    2015-01-01

    The aim of this experimental study was to evaluate and compare the chondroprotective efficacy of intra-articular hyaluronic acid, tenoxicam and vitamin E in osteoarthritis. An osteoarthritis model was created by anterior cruciate ligament transection and medial menisectomy in knees of 28 rats. The rats were randomized into four groups; first group served as a control group and received intra-articular injections of saline solution, intra-articular HA, intra-articular tenoxicam and intra-articular Vit E were applied to the treatment groups. First intra-articular injections were applied at second week postoperatively and repeated once a week for 5 weeks. At 8th week after the operation groups were compared based on the histologic scores of cartilage degeneration by Mankin Histological Grading Scale. Total cartilage degeneration score was significantly increased in the control group (P=0.004). Total Mankin scores of HA, tenoxicam and Vit E groups were significantly lower than the control group (P=0.004, P=0.016, P=0.012 respectively). There was no statistically siginificant difference between the treatment groups in terms of total Mankin scores (P>0.05). Intra-articular application of HA, tenoxicam and Vit E are chondroprotective in early osteoarthritis model in rats. Chondroprotective activity of tenoxicam and Vit E are comparable with the beneficial effects of HA on articular cartilage.

  6. Anestesia venosa total com infusão alvo-controlada de remifentanil e propofol para ablação de fibrilação atrial

    OpenAIRE

    Nora, Fernando Squeff; Pimentel, Maurício; Zimerman, Leandro Ioschpe; Saad, Eduardo B

    2009-01-01

    JUSTIFICATIVA E OBJETIVOS: A ablação de fibrilação atrial (FA) é um procedimento novo em nosso meio, embora seja comum em outros centros. A escolha da anestesia, monitores e cuidados anestesiológicos para esse procedimento, realizado fora do bloco cirúrgico, não tem sido descrita. O objetivo deste relato foi descrever uma técnica de anestesia para a realização de ablação de FA. RELATO DO CASO: Paciente feminina, 49 anos, 73 kg, 155 cm, ASA II por hipertensão arterial sistêmica. A monitorizaçã...

  7. Estudio Comparativo en Anestesia Raquídea: Bupivacaína 0,5% sin Epinefrina con Fentanil y sin Fentanil

    OpenAIRE

    Castillo Tianga, Rosa Herlinda

    2012-01-01

    La anestesia regional ocupa una parte importante del trabajo del anestesiólogo, lo cual incluye tanto técnica como drogas a utilizar, y tiene y una amplia aplicación en prácticamente todas las especialidades quirúrgicas, especialmente en ginecología, urología, traumatología, cirugía de abdomen bajo. La administración de anestesia regional implica tener conocimientos de anatomía y fisiología en cuanto a las vías nerviosas que conducen las señales sensitivas de dolor, tacto, temperatura y motor...

  8. Isquemia miocárdica silenciosa em pacientes submetidos à prostatectomia transuretral: comparação entre anestesia subaracnóidea e peridural

    OpenAIRE

    Gautam, Parshotam Lal; Katyal, Sunil; Wander, Gurpreet Singh; Kaur, Harpreet

    2004-01-01

    JUSTIFICATIVA E OBJETIVOS: A isquemia miocárdica silenciosa foi recentemente relacionada ao aumento de morbimortalidade cardíaca peri-operatória. Até 41% dos pacientes com doença coronariana conhecida ou fatores de risco cardíaco, submetidos à cirurgias não cardíacas, apresentaram isquemia peri-operatória. Vários autores compararam técnicas de anestesia regional e geral mas nenhum comparou o impacto de diferentes técnicas de anestesia no neuro-eixo na incidência e duração da isquemia miocárdi...

  9. Anestesia em criança com síndrome de Guillain-Barré após vacina de sarampo: relato de caso

    OpenAIRE

    Tonelli, Deoclécio; Sacco, Paula de Camargo Neves; Calegari, Desire; Cimerman, Gustavo; Santos, Carolina Mourão dos; Farath, Rodrigo Gonzales

    2005-01-01

    JUSTIFICATIVA E OBJETIVOS: A síndrome de Guillain-Barré após vacina de sarampo é rara. O diagnóstico muitas vezes é tardio, o que leva a um aumento da morbidade. O presente relato apresenta um caso avançado e os cuidados especiais exigidos durante a anestesia. RELATO DO CASO: Paciente do sexo masculino, com quatro anos de idade com síndrome de Guillain-Barré desde um ano de idade, foi submetido a gastrostomia sob anestesia geral sem intercorrências, com sevoflurano e sem bloqueadores neuromus...

  10. Estudio sobre la actividad anestésica en Cataluña: Resultados del análisis de 23.136 anestesias realizadas en el 2003.

    OpenAIRE

    Sabaté Tenas, Sergi

    2008-01-01

    ANESCAT es una encuesta pensada para cuantificar la actividad anestesiológica y los recursos humanos para realizarla. Se llevó a cabo un estudio prospectivo transversal en forma de encuesta realizada en 14 días aleatorios del año 2003. Participaron 131 centros sanitarios públicos y privados, el 100% de los que practicaron anestesias en el año 2003. Se recogieron 23.136 cuestionarios y se estimó que en el año 2003 se habían realizado en Cataluña 603.189 anestesias (intervalo de confianza del 9...

  11. Anestesia subtenoniana en cirugía de estrabismo Sub-Tenon's anesthesia in strabismus surgery

    Directory of Open Access Journals (Sweden)

    Rosa M. Naranjo Fernández

    2004-12-01

    Full Text Available Se realizó un estudio descriptivo, retrospectivo de 30 pacientes con el diagnóstico de estrabismo que acudieron al Servicio de Oftalmología Pediátrica y Estrabismo del Hospital Oftalmológico Docente "Ramón Pando Ferrer" y fueron operados con la técnica de anestesia subtenoniana desde abril de 2003 hasta mayo de 2004; se analizaron las variables: edad, entidad diagnostica y grado de dolor. Se encontró que el rango de edad que predominó fue de 20 a 39 años, la esotropía como el diagnóstico más frecuente, el grado de dolor fue significativo en la tracción muscular y la técnica anestésica subtenoniana resultó efectiva independientemente de la técnica quirúrgica aplicada, sin complicaciones y con buena analgesia.A descriptive and retrospective study of 30 patients with the diagnosis of strabismus that were operated on at the Service of Pediatric Ophthalmology and Strabismus of "Ramón Pando Ferrer" Ophthalmological Hospital by the technique of sub-Tenon's anesthesia from April 2003 to May 2004 was conducted.The following variables were analyzed: age, diagnostic entity and pain degree. It was found a predominance of the age range 20-39. Esotropia was the most frequent diagnosis. The pain degree was significant in the muscular traction and the sub-Tenon's anesthetic technique proved to be effective independently of the surgical technique applied, without complications and with good analgesia.

  12. Midazolan-Tiopental: compatibilidad y sinergismo farmacológico en anestesia pediátrica

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    Joaquín L de la Lastra Rodríguez

    1996-06-01

    Full Text Available La administración de tiopental ha sido recomendada para completar la inducción anestésica, cuando la dosis de midazolán ha sido insuficiente; además es reconocido el efecto de sinergismo entre ambos fármacos. El objetivo del trabajo fue analizar el beneficio que representa esta técnica de inducción en un grupo de 25 pacientes pediátricos, con la utilización de dosis de midazolán de 0,3 mg/kg de peso y de tiopental de 2,5 mg/kg de peso. Los resultados fueron satisfactorios y se observó la ausencia o la disminución de la respuesta hipertensora arterial después de la laringoscopia directa y de la intubación endotraqueal. El mantenimiento de la anestesia fue garantizado con una mezcla de oxígeno y de óxido nitroso y dosis intermitentes de fentaniloThe administration of thiopental has been recommended to complete anesthetic induction, when the dose of midazolam has not been sufficient; moreover, the sinergistic effect between both drugs is well know. The aim of this work was to analize the advantage of this induction technique in a group of 25 pediatric patients, with the use of a dose of 0.3 mg/kg midazolam and 2.5 mg/kg thiopental. Results were satisfactory and the absence or decrease of arterial hypertensive response after direct laryngoscopy and endotracheal intubation was observed. The maintenance of anesthesia was guaranteed by mixing nitrous oxide and intermittent doses of fentanyl

  13. Anestesia para mielografia em cães Anesthesia for myelography in dogs

    Directory of Open Access Journals (Sweden)

    Alessandra Valeiro Leite

    2002-08-01

    Full Text Available Com este texto, objetiva-se fornecer ao profissional de Medicina Veterinária subsídios para a realização de mielografia para o qual é necessário submeter o animal À anestesia geral. Este exame não é um procedimento inócuo, pois várias reações adversas podem ocorrer durante e após sua realização. O conhecimento da farmacodinâmica dos agentes anestésicos é de fundamental importância para o Médico Veterinário escolher associações que proporcionem segurança e minimizem as complicações advindas da técnica. Uma série de cuidados no período pré-anestésico, a escolha de associações de fármacos adequada e o monitoramento do animal durante e após a mielografia proporcionarão aos pacientes uma maior segurança no procedimento.The aim of this work was to supply the Veterinarian professional with information regarding to the execution of a mielography, which requires general anesthesia. This exam is not harmless and several adverse reactions may occur during and after its realization. The knowledge of the anesthetics pharmacodynamic is essential in order to select the associations that could provide safety and minimize the myelography complications. Some procedures in the preanesthetic period, the selection of the appropriate anesthetic agents and monitoring the animal during and after the myelography will provide major safety to this exam.

  14. Analgesia de parto: estudo comparativo entre anestesia combinada raquiperidural versus anestesia peridural contínua Analgesia de parto: estudio comparativo entre anestesia combinada raqui-peridural versus anestesia peridural continua Labor analgesia: a comparative study between combined spinal-epidural anesthesia versus continuous epidural anesthesia

    Directory of Open Access Journals (Sweden)

    Carlos Alberto de Figueiredo Côrtes

    2007-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O alívio da dor no trabalho de parto tem recebido atenção constante visando ao bem-estar materno, diminuindo o estresse causado pela dor e reduzindo as conseqüências deste sobre o concepto. Inúmeras técnicas podem ser utilizadas para analgesia de parto. Este trabalho teve como objetivo comparar a técnica peridural contínua com a combinada, ambas com o uso de bupivacaína a 0,25% em excesso enantiomérico 50% e fentanil como agentes. MÉTODO: Participaram do estudo 40 parturientes em trabalho de parto com dilatação cervical entre 4 e 5 cm que foram distribuídas em dois grupos iguais de forma aleatória. O Grupo I recebeu anestesia peridural contínua. O Grupo II recebeu anestesia combinada. Foram avaliados: medidas antropométricas, idade gestacional, dilatação cervical, tempo entre o bloqueio e a ausência de dor por meio da escala analógica visual, possibilidade de deambulação, tempo entre o início da analgesia e a dilatação cervical completa, duração do período expulsivo, parâmetros hemodinâmicos maternos e vitalidade do recém-nascido. Possíveis complicações, como depressão respiratória, hipotensão arterial materna, prurido, náuseas e vômitos, também foram observadas. Para a comparação das médias utilizou-se o teste t de Student e para a paridade e tipo de parto utilizou-se o teste do Qui-quadrado. RESULTADOS: Não houve diferença estatística significativa entre os dois grupos em relação ao tempo entre o início da analgesia e a dilatação cervical completa, bem como em relação ao tempo da duração do período expulsivo, incidência de cesariana relacionada com a analgesia, parâmetros hemodinâmicos maternos e vitalidade do recém-nascido. CONCLUSÕES: Ambas as técnicas se mostraram eficazes e seguras para a analgesia do trabalho de parto, embora a técnica combinada tenha proporcionado um rápido e imediato alívio da dor. Estudos clínicos com maior número de casos s

  15. ANESTESIA EM EQÜINOS COM DETOMIDINA E TILETAMINA-ZOLAZEPAM

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    Cláudio Corrêa Natalini

    1994-01-01

    Full Text Available RESUMO Seis eqüinos foram anestesiados, via intravenosa, com o cloridrato de detomidina 1% (0,03mg/kg, associado à combinação tiletamina-zolazepam 5% (1mg/kg. Foram registrados o tempo para obtenção do decúbito lateral e o tempo para retorno à posição de estação. As freqüências cardíaca e respiratória, a temperatura retal, os vaiores arteriais de pH, PCO2, PO2, HCO3, excesso de bases e SATO2, foram analisados no período anterior à sedação (valor basal, durante a anestesia e ao retorno à posição de estação. Dois eqüinos foram submetidos a procedimentos cirúrgicos. O tempo médio para a obtenção do decúbito lateral foi de 53,80 ± 9,06 segundos. O período médio em decúbito lateral foi de 28,50 ± 5,05 minutos e o tempo para retorno à estação foi de 39,16 ± 4,59 minutos. A análise hemogasométrica arterial revelou a ocorrência de hipoxemia no período anestésico. As freqüências cardíaca, respiratória e temperatura retal mantiveram-se estáveis no período estudado.

  16. Occult Intra-articular Knee Injuries in Children With Hemarthrosis.

    Science.gov (United States)

    Askenberger, Marie; Ekström, Wilhelmina; Finnbogason, Thröstur; Janarv, Per-Mats

    2014-07-01

    Hemarthrosis after acute knee trauma is a sign of a potentially serious knee injury. Few studies have described the epidemiology and detailed injury spectrum of acute knee injuries in a general pediatric population. To document the current injury spectrum of acute knee injuries with hemarthrosis in children aged 9 to 14 years and to describe the distribution of sex, age at injury, type of activity, and activity frequency in this population. Descriptive epidemiology study. All patients in the Stockholm County area aged 9 to 14 years who suffered acute knee trauma with hemarthrosis were referred to Astrid Lindgren Children's Hospital, Karolinska University Hospital, from September 2011 to April 2012. The patients underwent clinical examination, radiography, and magnetic resonance imaging (MRI). The type of activity when injured, regular sports activity/frequency, and patient sex and age were registered. The diagnoses were classified into minor and serious injuries. The study included 117 patients (47 girls and 70 boys; mean age, 13.2 years). Seventy percent had a serious knee injury. Lateral patellar dislocations, anterior cruciate ligament ruptures, and anterior tibial spine fractures were the most common injuries, with an incidence of 0.6, 0.2, and 0.1 per 1000 children, respectively. The sex distribution was equal up to age 13 years; twice as many boys were seen at the age of 14 years. The majority of injuries occurred during sports. Forty-six patients (39%) had radiographs without a bony injury but with a serious injury confirmed on MRI. Seventy percent of the patients aged 9 to 14 years with traumatic knee hemarthrosis had a serious intra-articular injury that needed specific medical attention. Fifty-six percent of these patients had no visible injury on plain radiographs. Physicians who treat this group of patients should consider MRI to establish the diagnosis when there is no or minimal radiographic findings. The most common serious knee injury was a lateral

  17. Intra-articular injection of dexketoprofen in rat knee joint: histopathologic assessment of cartilage & synovium.

    Science.gov (United States)

    Ekici, Aycan Guner; Akyol, Onat; Ekici, Murat; Sitilci, Tolga; Topacoglu, Hakan; Ozyuvaci, Emine

    2014-08-01

    Effective pain control following outpatient surgical procedures is an important aspect of patient discharge. This study was carried out with an aim to investigate the histopathological effects of intra-articular dexketoprofen trometamol injection in knee joint on synovium and cartilage in an experimental rat model. In each of 40 rats, the right knee was designated as the study group and the left knee as the control group (NS group). Under aseptic conditions, 35 rats received an injection of 0.25 ml (6.25 mg) dexketoprofen trometamol into the right knee joint and an injection of 0.25 ml 0.9 per cent normal saline solution into the left knee joint. On the 1st, 2nd, 7th, 14th, and 21st days after intra-articular injection, rats in specified groups were sacrificed by intraperitoneal injection of 120 mg/kg sodium thiopental. Knee joints were separated and sectioned for histopathological examination. Inflammatory changes in the joints were recorded according to a grade scale. No significant difference in terms of pathological changes both in synovium and cartilage was observed between the NS group and the study group on days 1, 2, 7, 14 and 21 after intra-articular injection of dexketoprofen or saline in the knee joint. The findings showed no evidence of significant histopathological damage to the cartilage and synovia for a period up to 21 days following intra-articular administration of dexketoprofen trometamol in the knee joints of rats.

  18. The Effect of Preoperative Intra-Articular Methylprednisolone on Pain After TKA

    DEFF Research Database (Denmark)

    Luna, Iben E; Kehlet, Henrik; Jensen, Claus M

    2017-01-01

    In a randomized, double-blind, placebo controlled trial, we investigated the postoperative analgesic effect of a single intra-articular injection of 40 mg methylprednisolone acetate (MP) administered 1 week before total knee arthroplasty (TKA). Forty-eight patients with high pain osteoarthritis (...

  19. Intra-Articular Analgesia and Steroid Reduce Pain Sensitivity in Knee OA Patients

    DEFF Research Database (Denmark)

    Jørgensen, Tanja Schjødt; Graven-Nielsen, Thomas; Ellegaard, Karen

    2014-01-01

    before, immediately after, and two weeks after ultrasound guided intra-articular injection of lidocaine combined with glucocorticosteroid. Computer-controlled and manual pressure algometers were used to assess PPT on the knee, vastus lateralis, tibialis anterior, and the extensor carpi radialis longus...

  20. Intra-articular calcaneal fracture in a 14-year-old competing skier: case report.

    Science.gov (United States)

    Tudor, Anton; Sestan, Branko; Nemec, Boris; Prpic, Tomislav; Rubinic, Dusan

    2003-12-01

    Intra-articular calcaneal fracture as a skiing injury in children is extremely rare. We report on what we believe is a unique and previously unreported mechanism of a skiing injury, which caused intra-articular calcaneal fracture in a young competing skier, a member of the Croatian national ski team. This 14-year-old boy sustained a heel injury while training for giant slalom. There was no fall on the heel or obvious axial force that could have caused this type of calcaneal fracture. The skier had sophisticated equipment and used carving skies. We speculated that, when the skier tried to establish the lost balance during the fall, a violent contraction of triceps muscle occurred. Instead of an injury of a well-protected tuber or Achilles tendon, the strong pulling force of the Achilles tendon was transmitted more distally and anteriorly, generating axial compression force, which caused an intra-articular fracture of the calcaneus bone. Obviously, the existing ski boot did not sufficiently protect the calcaneus bone. We postulate that the calcaneal tuber and Achilles tendon were protected on the expense of the intra-articular calcaneal fracture. Our case warns of the possibility of a serious foot injury in young top skiers in spite of extensive improvement in the ski equipment. Sophisticated carving skis could be a contributing factor to an injury.

  1. Intra-articular injection of tenoxicam in osteoarthritic knee joints with effusion.

    Science.gov (United States)

    Oztuna, Volkan; Eskandari, Metin; Bugdayci, Resul; Kuyurtar, Fehmi

    2007-12-01

    Thirty patients who had grade II to III osteoarthritis according to Kellgren-Lawrence system and presenting with acute effusion of the knee joint were randomly assigned to 2 groups. All patients were treated with aspiration of the synovial fluid, cold application, and rest. Fifteen patients received an intra-articular injection of tenoxicam 20 mg following aspiration. The other group was administered oral tenoxicam 20 mg a day for 10 days. Patients were examined at 2, 4, and 8 weeks and then in 3-month intervals. At followup visits, pain was assessed using visual analog scale: range of motion, and effusion of the knee joint were recorded. A repeated measure test was used to determine the significance of changes in pain and mobility between the groups. Student's Neyman Keuls test was used to determine the significance of differences within the groups. Chi-square test was used for the number of episodes. The intra-articular injection group had more rapid pain relief than the oral treatment group (P < .01). At the end of 1 year, the number of effusions was significantly lower in the intra-articular treatment group (P < .01). These results indicate that intra-articular injection of tenoxicam provides rapid pain relief in the patients with acute flare-up of knee osteoarthritis and helps to prevent effusion.

  2. Surgical treatment of intra-articular fractures of the distal part of the humerus

    NARCIS (Netherlands)

    Doornberg, Job N.; van Duijn, Pleun J.; Linzel, Durk; Ring, David C.; Zurakowski, David; Marti, Rene K.; Kloen, Peter

    2007-01-01

    Background: The short-term results of open reduction and internal fixation of intra-articular distal humeral fractures are good to excellent in approximately 75% of patients, but the long-term results have been less well studied. This investigation addressed the long-term clinical and radiographic

  3. The effectiveness of hyaluronic acid intra-articular injections in managing osteoarthritic knee pain

    Science.gov (United States)

    Anand, A

    2013-01-01

    Introduction Knee osteoarthritis (OA) is a common and progressive joint disease. Treatment options for knee OA vary from simple analgesia in mild cases to knee replacement for advanced disease. Knee pain due to moderate OA can be targeted with intra-articular injections. Steroid injections have been used widely in managing acute flare-ups of the disease. In recent years, viscosupplementation has been used as a therapeutic modality for the management of knee OA. The principle of viscosupplementation is based on the physiological properties of the hyaluronic acid (HA) in the synovial joint. Despite a sound principle and promising in vitro studies, clinical studies have been less conclusive on the effectiveness of HA in managing osteoarthritic knee pain. The aim of this systematic review was to assess the effectiveness of HA intra-articular injections in the management of osteoarthritic knee pain. Methods A systematic review of the literature was performed using MEDLINE®, Embase™ and CINAHL® (Cumulative Index to Nursing and Allied Health Literature). The databases were searched for randomised controlled trials available on the effectiveness of HA intra-articular injections in managing osteoarthritic knee pain. Results The search yielded 188 studies. Of these, 14 met the eligibility criteria and were reviewed in chronological order. Conclusions HA intra-articular injections have a modest effect on early to moderate knee OA. The effect peaks at around 6–8 weeks following administration, with a doubtful effect at 6 months. PMID:24165334

  4. Displaced Intra-articular Fractures of the Calcaneus: with an emphasis on minimally invasive surgery

    NARCIS (Netherlands)

    T. Schepers (Tim)

    2009-01-01

    textabstractDisplaced intra-articular calcaneal fractures are complex injuries. Classically these fractures are treated with open reduction and internal fixation (ORIF) or conservatively. When comparing these two treatment modalities, ORIF has a significantly higher rate of wound complications and

  5. Treatment of displaced intra-articular calcaneal fractures by ligamentotaxis: Current concepts' review

    NARCIS (Netherlands)

    T. Schepers (Tim); P. Patka (Peter)

    2009-01-01

    textabstractIntroduction: A large variety of therapeutic modalities for calcaneal fractures have been described in the literature. No single treatment modality for displaced intra-articular calcaneal fractures has proven superior over the other. This review describes and compares the different

  6. A comparison of analgesic effect of intra-articular levobupivacaine with bupivacaine following knee arthroscopy

    International Nuclear Information System (INIS)

    Karaman, Yucel; Bor, Canan; Kayali, Cemil; Ozturk, Hasan; Kaya, Ahmet

    2009-01-01

    To compare the postoperative analgesic effects of intra-articular levobupivacaine with bupivacaine following knee arthroscopy. Forty patients, aged between 20-60 years and undergoing elective knee arthroscopy were enrolled into the study protocol that was carried out in Tepecik Education and Research Hospital, Izmir, Turkey between January and June 2007. General anesthesia protocol was the same in all patients. At the end of surgery, the patients were randomly assigned into 2 groups (n=20 in each group). Group L received 20 ml 0.5% levobupivacaine and Group B received 20 ml 0.5% bupivacaine intra-articularly. We evaluated the level of postoperative pain (by visual analoque scale at 1, 2, 4, 6, 12, and 24 hours after surgery), first analgesic requirement time (period measured from the end of the surgery until further analgesia was demanded), and total analgesic consumption during 24 hours. There were no significant difference in the postoperative pain scores of the patients between groups. The first analgesic requirement times were not statistically different. Twelve patients in Group L (60%) and 9 patients in Group B (45%) needed no additional analgesic during the 24 hours (p>0.05). No complications and side effects were found related to the intra-articular treatment. The results of the study show that intra-articular 20 ml 0.5% levobupivacaine provides effective analgesia comparable to that provided by 20 ml 0.5% bupivacaine. (author)

  7. Treatment of displaced intra-articular calcaneal fractures with closed reduction and percutaneous screw fixation

    NARCIS (Netherlands)

    Tomesen, T.; Biert, J.; Frolke, J.P.M.

    2011-01-01

    BACKGROUND: Surgical treatment of displaced intra-articular fractures of the calcaneus is a standard procedure in many institutions. To avoid soft-tissue complications, several minimally invasive procedures have recently been introduced. The aim of this study was to assess the percutaneous treatment

  8. Anestesia venosa total com infusão alvo-controlada de remifentanil e propofol para ablação de fibrilação atrial Anestesia venosa total con infusión objeto-controlada de remifentanil y propofol para ablación de la fibrilación atrial Total intravenous anesthesia with target-controlled infusion of remifetanil and propofol for ablation of atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Fernando Squeff Nora

    2009-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A ablação de fibrilação atrial (FA é um procedimento novo em nosso meio, embora seja comum em outros centros. A escolha da anestesia, monitores e cuidados anestesiológicos para esse procedimento, realizado fora do bloco cirúrgico, não tem sido descrita. O objetivo deste relato foi descrever uma técnica de anestesia para a realização de ablação de FA. RELATO DO CASO: Paciente feminina, 49 anos, 73 kg, 155 cm, ASA II por hipertensão arterial sistêmica. A monitorização constou de eletrocardiograma com 12 derivações, oximetria de pulso, frequência cardíaca, eletroencefalografia bispectral para medidas de BIS, taxa de supressão (SR e SEF95 e pressão arterial média (PAM. A indução anestésica foi realizada com propofol por via venosa, em infusão alvo-controlada (IAC, com alvo regulado em 4 µg.mL-1, remifentanil por via venosa, em IAC, com alvo de 3 ng.mL¹, e rocurônio por via venosa em bolus na dose de 0,2 mg.kg-1. O modelo farmacocinético de propofol utilizado foi o descrito por Marsh e incorporado à bomba de propofol PFS®. O modelo farmacocinético de remifentanil utilizado foi o descrito por Minto e incorporado à bomba de infusão Alaris PK®. As concentrações, no local efetor ou biofase, corresponderam às informações obtidas através das bombas de infusão e representaram medidas preditivas das concentrações de ambos os fármacos nos respectivos locais de ação. As concentrações de propofol e de remifentanil foram reguladas de acordo com o BIS e a PAM, respectivamente. CONCLUSÕES: A anestesia venosa total para ablação de FA pode ser uma opção segura, levando-se em conta que não há alteração da eletrofisiologia das vias acessórias. A literatura é escassa a este respeito e novas publicações poderão ou não justificar esta modalidade de anestesia durante ablação de FA.JUSTIFICATIVA Y OBJETIVOS: La ablación de fibrilación atrial (FA es un procedimiento nuevo en

  9. Pharmacokinetics of triamcinolone acetonide following intramuscular and intra-articular administration to exercised Thoroughbred horses.

    Science.gov (United States)

    Knych, H K; Vidal, M A; Casbeer, H C; McKemie, D S

    2013-11-01

    The use of triamcinolone acetonide (TA) in performance horses necessitates establishing appropriate withdrawal times prior to performance. To describe the plasma pharmacokinetics of TA and time-related urine and synovial fluid concentrations following i.m. and intra-articular administration to exercised Thoroughbred horses. Block design. Twelve racing fit adult Thoroughbred horses received a single i.m. administration of TA (0.1 mg/kg bwt). After an appropriate washout period, the same horses then received a single intra-articular TA administration (9 mg) into the right antebrachiocarpal joint. Blood, urine and synovial fluid samples were collected prior to, and at various times, up to 60 days post drug administration and analysed using liquid chromatography-mass spectrometry. Plasma data were analysed using noncompartmental analysis. Maximum measured plasma TA concentrations were 0.996 ± 0.391 at 13.2 h and 1.27 ± 0.278 ng/ml at 6.5 h for i.m. and intra-articular administration, respectively. The plasma terminal elimination half-life was 11.4 ± 6.53 and 0.78 ± 1.00 days for i.m. and intra-articular administration, respectively. Following i.m. administration, TA was below the limit of detection (LOD) by Days 52 and 60 in plasma and urine, respectively. Following intra-articular administration TA was undetectable by Day 7 in plasma and Day 8 in urine. Triamcinolone acetonide was also undetectable in any of the joints sampled following i.m. administration and remained above the limit of quantitation (LOQ) for 21 days following intra-articular administration. This study extends previous studies describing the pharmacokinetics of TA following i.m. and intra-articular administration to the horse and suggests that plasma and urine concentrations are not a good indicator of synovial fluid concentrations. Furthermore, results of this study supports an extended withdrawal time for TA given i.m. © 2013 EVJ Ltd.

  10. Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis

    International Nuclear Information System (INIS)

    Zhang, Z.; Huang, G.

    2012-01-01

    The objective of this paper is to provide readers with current developments of intra-articular drug delivery systems. In recent years, although the search for a clinically successful ideal carrier is ongoing, sustained-release systems, such as polymeric micro- and nanoparticles, liposomes, and hydrogels, are being extensively studied for intra-articular drug delivery purposes. The advantages associated with long-acting preparations include a longer effect of the drug in the action site and a reduced risk of infection due to numerous injections consequently. This paper discusses the recent developments in the field of intra-articular sustained-release delivery systems for the treatment of osteoarthritis

  11. Anestesia ambulatorial para radioterapia em paciente portador de miastenia gravis: relato de caso Anestesia ambulatorial para radioterapia en paciente portador de miastenia gravis: relato de caso Outpatient anesthesia for radiotherapy in a patient with myasthenia gravis: case report

    Directory of Open Access Journals (Sweden)

    Raquel Marcondes Bussolotti

    2006-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A miastenia gravis (MG é doença auto-imune rara, caracterizada pela redução de receptores nicotínicos na junção neuromuscular, com incidência de 14/100.000. O objetivo deste relato foi descrever o caso de paciente portador de miastenia gravis submetido à anestesia geral balanceada, para tratamento radioterápico de carcinoma espinocelular de parótida, em regime ambulatorial. RELATO DO CASO: Paciente do sexo masculino, 87 anos, 87 kg, estado físico ASA III, com história de miastenia gravis; acidente vascular encefálico prévio (AVE; marca-passo por bloqueio atrioventricular total; hipertensão arterial sistêmica (HAS. Foram programadas sete sessões de radioterapia de 20 minutos para tratamento de tumor de parótida, sob anestesia geral. Na sala de radioterapia foi monitorizado com cardioscópio, monitor de pressão arterial não-invasiva, oxímetro de pulso, e submetido à anestesia geral com propofol e sevoflurano. Após a indução, foi mantido em ventilação espontânea com cânula de Guedel e cateter nasofaríngeo com O2 /sevoflurano, para acomodação da máscara imobilizadora. Na sala de recuperação pós-anestésica, não apresentou complicações. CONCLUSÕES: A escolha dos anestésicos e o acompanhamento clínico criterioso permitiram a boa evolução do paciente, com AVE prévio, cardiopata e idoso, submetido à anestesia geral balanceada para procedimento de aplicação de radioterapia, em regime ambulatorial.JUSTIFICATIVA Y OBJETIVOS: La Miastenia Gravis (MG es una enfermedad auto inmune rara, caracterizada por la reducción de receptores nicotínicos en la junción neuromuscular, con incidencia de 14/100.000. El objetivo de este relato fue el de describir el caso del paciente portador de miastenia gravis sometido a la anestesia general balanceada, para tratamiento radioterápico de carcinoma espinocelular de parótida en régimen ambulatorial. RELATO DEL CASO: Paciente del sexo masculino

  12. Avaliação de relatório eletrônico de anestesia Evaluación de informe electrónico de anestesia Evaluation of a computerized anesthesia report

    Directory of Open Access Journals (Sweden)

    Raffael Pereira Cezar Zamper

    2010-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A utilização de sistemas de informação que permitem o preenchimento automático de relatórios de anestesia ainda é incipiente no Brasil. O objetivo deste estudo foi validar um sistema informatizado para elaboração de relatório de anestesia. MÉTODOS: O projeto foi aprovado pela Comissão de Ética institucional e desenvolvido em sistema de parceria empresa-universidade (Dixtal, São Paulo, Brasil e Universidade de São Paulo com financiamento da FINEP (Financiadora de Estudos e Projetos do Ministério de Ciência e Tecnologia. O projeto elaborado teve como premissa a integração ao sistema de informações hospitalares para recuperação de dados referentes à identificação, avaliação pré-operatória e resultados de exames laboratoriais. A versão final do protótipo do sistema informatizado desenvolvido foi submetida à avaliação com relação à aplicabilidade por meio de instrumento semiestruturado, aplicado a 33 médicos, residentes e/ou especialistas em Anestesiologia durante procedimentos anestésico-cirúrgicos realizados em 66 pacientes. Os dados foram avaliados descritivamente. RESULTADOS: O sistema informatizado avaliado foi considerado con fiável por 81% dos participantes, inclusive para cirurgias de grande porte. A maioria dos anestesiologistas considerou o protótipo proveitoso para a realização de pesquisas futuras e capaz de atender às necessidades de confecção de relatório de anestesia, com benefícios para anestesiologistas, pacientes e hospital. O sistema exige treinamento para uso completo e pode ser aprimorado em alguns aspectos. CONCLUSÕES: A validação desse protótipo de sistema informatizado para elaboração de relatório de anestesia mostrou a viabilidade desse tipo de solução para auxiliar os anestesiologistas em suas atividades diárias, aumentando a confiabilidade dos dados. Além disso, na avaliação da aplicabilidade, os anestesistas consideraram que o prot

  13. Bloqueio dos nervos ilioinguinal e iliohipogástrico guiado por ultra-sonografia associado à anestesia geral: relato de caso Bloqueo de los nervios íleoinguinal e íleohipogástrico guiado por ultrasonografía asociado a anestesia general: relato de caso Ultrasound-guided ileoinguinal and ileohypogastric nerve block associated with general anesthesia: case report

    Directory of Open Access Journals (Sweden)

    Diogo Brüggemann da Conceição

    2008-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Procedimentos cirúrgicos realizados em regime ambulatorial estão se tornando mais freqüentes. O bloqueio dos nervos ilioinguinal e iliohipogástrico tem sido usado para analgesia pós-operatória de pacientes submetidos à herniorrafia inguinal em regime ambulatorial. A ultra-sonografia auxilia as técnicas de anestesia regional possibilitando mais precisão no depósito do anestésico local ao redor dos nervos. O objetivo deste relato foi apresentar um caso de bloqueio dos nervos ilioinguinal e iliohipogástrico guiado por ultra-sonografia em paciente agendado para herniorrafia inguinal em regime ambulatorial. RELATO DO CASO: Paciente do sexo masculino, 36 anos, 74 kg, estado físico ASA I, agendado para realização de herniorrafia inguinal. Foi realizado o bloqueio dos nervos ilioipogástrico e ilioinguinal guiado por ultra-sonografia com ropivacaína a 0,5% e, em seguida, realizada anestesia venosa total. O paciente recebeu alta hospitalar quatro horas após o procedimento com escore de dor avaliado pela Escala Analógica Verbal de 3. CONCLUSÕES: O bloqueio dos nervos iliohipogástrico e ilioinguinal guiado por ultra-sonografia em pacientes submetidos à herniorrafia inguinal em regime ambulatorial pode ser utilizado no auxílio do controle da dor pós-operatória.JUSTIFICATIVA Y OBJETIVOS: Procedimientos quirúrgicos realizados en régimen ambulatorial se están convirtiendo cada vez más frecuentes. El bloqueo de los nervios íleoinguinal e íleohipogástrico ha sido usado para la analgesia postoperatoria de pacientes sometidos a la herniorrafia inguinal en régimen ambulatorial. La ultrasonografía auxilia las técnicas de anestesia regional posibilitando una mayor precisión en el depósito del anestésico local el rededor de los nervios. El objetivo de este relato fue presentar un caso de bloqueo de los nervios íleoinguinal e íleohipogástrico guiado por ultrasonografía en paciente a realizar

  14. SINERGISMO FARMACODINÁMICO. A PROPÓSITO DE UN CASO INTERVENIDO QUIRÚRGICAMENTE DE URGENCIA BAJO ANESTESIA GENERAL.

    Directory of Open Access Journals (Sweden)

    Yesid Pallares Villarreal

    2004-01-01

    Full Text Available Presentamos una paciente femenina geriatrica con antecedentes de hipertensiòn arterial y trastornos psiquiatricos intervenida quirurgicamente de urgencia por un cuadro doloroso abdominal, con una interaccion farmacodinamica por sinergismo del doxepin y captopril potenciada por los efectos de la anestesia general. La hipotensiòn arterial fue la forma clínica de presentación. La paciente se recibió hipotensa por la administración preoperatoria de doxepin tratamiento de base y de captopril tratamiento impuesto por crisis hipertensiva antes de su llegada al hospital. Después de la inducción de la anestesia general desarrolla hipotensión arterial que sólo responde a la administración de noradrenalina. En un inicio se interpreta como un shock séptico en fase hipodinámica por el cuadro doloroso abdominal y la vasoplejia pero descartadas otras causas se concluye como hipotensión arterial de origen farmacológico con relación a la ingestión de antidepresivos triciclicos e inhibidores de la enzima convertora de angiotensina I en angiotensina II por su acción sobre el sistema nervioso simpático por potenciada por los agentes anestésicos. La paciente fue dada de alta del hospital satisfactoriamente a los 7 dias de operada.

  15. Fresh gas low flow anesthesia in dogs/ Anestesia com fluxo baixo de gases frescos em cães

    Directory of Open Access Journals (Sweden)

    Newton Nunes

    2003-05-01

    Full Text Available With this work, the authors provide information about low flow anesthesia in dogs. They comment about the use of this technique, its advantages and disadvantages, and a comparative evaluation about volatile anesthetics regarding to their efficiency and safety when used in low flow anesthesia. Complementary, it was aimed to update the professionals that work with Veterinary Anesthesiology, through new papers and reports.Com este trabalho, os autores procuram fornecer informações sobre a anestesia com fluxo baixo em cães. São tecidas considerações relativas ao emprego da técnica, suas vantagens e restrições de uso, bem como a avaliação comparativa dos anestésicos voláteis quanto à sua eficiência e segurança quando utilizados sob anestesia com fluxo baixo de gases frescos. Complementarmente, procurou-se atualizar com literatura recente os conhecimentos dos profissionais que militam na área de Anestesiologia Veterinária.

  16. Emprego do propofol, isofluorano e morfina para a anestesia geral de longa duração em bezerros

    Directory of Open Access Journals (Sweden)

    Alves G.E.S.

    2003-01-01

    Full Text Available Foram estudadas características da bioquímica do sangue, da pressão arterial e da freqüência de pulso de 12 bezerros mantidos sob anestesia por 13 horas, utilizando-se propofol para a indução e isofluorano para manutenção, associados à administração de morfina intra-tecal. Os valores de freqüência de pulso, pressão arterial e glicemia apresentaram pequenas variações e se mantiveram próximos dos valores de referência para bezerros anestesiados. Ao longo do período de anestesia houve aumento significativo, mas discreto, do hematócrito, hemoglobina, pCO2, CO2 total, bicarbonato e potássio. O pH do sangue, pO2, Na+ e Ca++ apresentaram reduções significativas. Este protocolo anestésico foi seguro para a manutenção de bezerros anestesiados por período prolongado.

  17. Efeitos do óxido nitroso em hipotensão controlada durante anestesia com baixo fluxo

    Directory of Open Access Journals (Sweden)

    Semiha Barçın

    2013-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Investigamos o efeito do óxido nitroso (N2O em hipotensão controlada durante anestesia com baixo fluxo (isoflurano-dexmedetomidina em termos de hemodinâmica, consumo de anestésico e custos. MÉTODOS: Quarenta pacientes foram randomicamente alocados em dois grupos. Infusão de dexmedetomidina (0,1 µg.kg-1.min-1 foi mantida por 10 minutos. Subsequentemente, essa infusão foi mantida até os últimos 30 minutos de operação a uma dose de 0,7 µg.kg-1.hora-1. Tiopental (4-6 mg.kg-1 e brometo de vecurônio (0,08 0,12 mg.kg-1 foram administrados na indução de ambos os grupos. Isoflurano (2% foi administrado para manutenção da anestesia. O Grupo N recebeu uma mistura de 50% de O2-N2O e o Grupo A recebeu uma mistura de 50% de O2-ar como gás de transporte. Anestesia com baixo fluxo (1 L.min-1 foi iniciada após um período de 10 minutos de alto fluxo inicial (4,4 L.min-1. Os valores de pressão arterial, frequência cardíaca, saturação periférica de O2, isoflurano inspiratório e expiratório, O2 inspiratório e expiratório, N2O inspiratório e expiratório, CO2 inspiratório, concentração de CO2 após expiração e concentração alveolar mínima foram registrados. Além disso, as taxas de consumo total de fentanil, dexmedetomidina e isoflurano, bem como de hemorragia, foram determinadas. RESULTADOS: A frequência cardíaca diminuiu em ambos os grupos após a carga de dexmedetomidina. Após a intubação, os valores do Grupo A foram maiores nos minutos um, três, cinco, 10 e 15. Após a intubação, os valores de hipotensão desejados foram alcançados em 5 minutos no Grupo N e em 20 minutos no grupo A. Os valores da CAM foram mais altos no Grupo N nos minutos um, três, cinco, 10 e 15 (p < 0,05. Os valores da FiO2 foram mais altos entre 5 e 60 minutos no Grupo A, enquanto foram mais altos no Grupo N aos 90 minutos (p < 0,05. Os valores de Fi Iso (isoflurano inspiratório foram menores no Grupo N nos minutos

  18. Intraarticular glucocorticoid, morphine and bupivacaine reduces pain and convalescence after arthroscopic ankle surgery: a randomized study of 36 patients

    DEFF Research Database (Denmark)

    Rasmussen, S; Kehlet, H

    2000-01-01

    In a double-blind randomized study, 36 patients undergoing arthroscopic removal of bony spurs and synovitis causing impingement of the ankle were allocated to intraarticular saline or bupivacaine 15 mg + morphine 5 mg + intraarticular methylprednisolone 40 mg. Combined methylprednisolone, bupivac......In a double-blind randomized study, 36 patients undergoing arthroscopic removal of bony spurs and synovitis causing impingement of the ankle were allocated to intraarticular saline or bupivacaine 15 mg + morphine 5 mg + intraarticular methylprednisolone 40 mg. Combined methylprednisolone......, bupivacaine and morphine reduced pain, joint swelling, time of immobilization, duration of sick leave and return to sports after the arthroscopic procedure. In the treatment group, 1 patient had transitory purulent arthritis requiring antibiotics and arthroscopic synovectomy occurred....

  19. Rehabilitation after arthroscopic repair of intra-articular disorders of the hip in a professional football athlete.

    Science.gov (United States)

    Philippon, Marc J; Christensen, Jesse C; Wahoff, Michael S

    2009-02-01

    To report the 4-phase rehabilitation progression of a professional athlete who underwent arthroscopic intra-articular repair of the hip after injury during the 2006-07 season. Case study; level of evidence, 4. Objective values were obtained by standard goniometric measurements, handheld dynamometer, dynamic sports testing, and clinical testing for intra-articular pathology. This case report illustrates improvements in hip mobility, muscle-force output, elimination of clinical signs of intra-articular involvement, and ability to perform high-level sport-specific training at 9 wk postsurgery. At 16 wk postsurgery, the patient was able to return to full preparation for sport for the following season. After the 4-phase rehabilitation program, the patient demonstrated improvement in all areas of high-level function after an arthroscopic intra-articular repair of the hip. The preoperative management to return to sport is outlined, with clinical outcomes and criteria for return to competition.

  20. Anestesia general y analgesia para la resolución de una hernia peritoneapericárdica congenita en perro: caso clínico

    OpenAIRE

    Costa, Margarida; Alexandre, Nuno; Alves, Ricardo; Bação, Maria; Martín, Maria; Garcia, Monica; Celdrán, Diego; Lima, Juan; Sánchez, Francisco

    2010-01-01

    O objectivo deste trabalho foi proporcionar uma anestesia inalatória e analgesia multimodal segura e eficaz num caso clínico de uma reparação cirúrgica de uma hérnia peritoneopericárdica num cão

  1. Anestesia en la operación de Blalock-Taussig

    Directory of Open Access Journals (Sweden)

    Lincoln de la Parte Pérez

    2001-09-01

    Full Text Available A pesar de los avances en la última década de las técnicas quirúrgicas para la reparación total de los defectos congénitos cianóticos del corazón, aún algunos pacientes necesitan procedimientos quirúrgicos paliativos durante los primeros meses de vida. Se presenta un estudio retrospectivo de 160 pacientes operados con la técnica paliativa de Blalock-Taussig, en el Cardiocentro del Hospital Pediátrico Universitario "William Soler", en el período de 1990 a 1993. Padecían de Tetralogía de Fallot 120 pacientes, 35 de atresia pulmonar y el resto 5, de transposición de los grandes vasos. El fentanyl fue el agente más utilizado en la inducción y mantenimiento de la anestesia y aportó gran estabilidad hemodinámica. Las complicaciones transoperatorias más frecuentes fueron las arritmias cardíacas (25 pacientes, 15,6 % y dentro de éstas, la mayoría extrasístoles ventriculares (18 pacientes. No hubo fallecidos durante el transoperatorio.In spite of the advances achieved by the surgical techniques for the total repair of congenital cyanotic heart defects in the last decade, some patients still need palliative surgical procedures during the first months of life. A retrospective study of 160 patients that were operated on by using Blalock-Taussig palliative technique at the Heart Center of "William Soler" Pediatric Teaching Hospital, from 1990 to 1993, was conducted. 120 patients suffered from Tetralogy of Fallot, 35 from pulmonary atresia, and the other 5 from transposition of great vessels. Fentanyl was the most used agent in the induction and maintenance of anesthesia and it produced a high hemodynamic stability. The most common transoperative complications were cardiac arrhytmias (25 patients, 15.6 % and, within them, the most were ventricular extrasystoles (18 patients. There were no deaths during the transoperative.

  2. Intraarticular glucocorticoid, morphine and bupivacaine reduces pain and convalescence after arthroscopic ankle surgery: a randomized study of 36 patients

    DEFF Research Database (Denmark)

    Rasmussen, S; Kehlet, H

    2000-01-01

    , bupivacaine and morphine reduced pain, joint swelling, time of immobilization, duration of sick leave and return to sports after the arthroscopic procedure. In the treatment group, 1 patient had transitory purulent arthritis requiring antibiotics and arthroscopic synovectomy occurred.......In a double-blind randomized study, 36 patients undergoing arthroscopic removal of bony spurs and synovitis causing impingement of the ankle were allocated to intraarticular saline or bupivacaine 15 mg + morphine 5 mg + intraarticular methylprednisolone 40 mg. Combined methylprednisolone...

  3. Intra-articular temperatures of the knee in sports - an in-vivo study of jogging and alpine skiing.

    Science.gov (United States)

    Becher, Christoph; Springer, Jan; Feil, Sven; Cerulli, Guiliano; Paessler, Hans H

    2008-04-11

    Up to date, no information exists about the intra-articular temperature changes of the knee related to activity and ambient temperature. In 6 healthy males, a probe for intra-articular measurement was inserted into the notch of the right knee. Each subject was jogging on a treadmill in a closed room at 19 degrees C room temperature and skiing in a ski resort at -3 degrees C outside temperature for 60 minutes. In both conditions, temperatures were measured every fifteen minutes intra-articulary and at the skin surface of the knee. A possible influence on joint function and laxity was evaluated before and after activity. Statistical analysis of intra-articular and skin temperatures was done using nonparametric Wilcoxon's sign rank sum test and Mann-Whitney's-U-Test. Median intra-articular temperatures increased from 31.4 degrees C before activity by 2.1 degrees C, 4 degrees C, 5.8 degrees C and 6.1 degrees C after 15, 30, 45 and 60 min of jogging (all p jogging), the median intra-articular temperature was 19.6% (8.7%) higher than the skin surface temperature at the knee. Joint function and laxity appeared not to be different before and after activity within both groups. This study demonstrates different changes of intra-articular and skin temperatures during sports in jogging and alpine skiing and suggests that changes are related to activity and ambient temperature.

  4. The Use of an Intra-Articular Depth Guide in the Measurement of Partial Thickness Rotator Cuff Tears

    Directory of Open Access Journals (Sweden)

    Michael J. Carroll

    2013-01-01

    Full Text Available Purpose. The purpose of this study was to compare the accuracy of the conventional method for determining the percentage of partial thickness rotator cuff tears to a method using an intra-articular depth guide. The clinical utility of the intra-articular depth guide was also examined. Methods. Partial rotator cuff tears were created in cadaveric shoulders. Exposed footprint, total tendon thickness, and percentage of tendon thickness torn were determined using both techniques. The results from the conventional and intra-articular depth guide methods were correlated with the true anatomic measurements. Thirty-two patients were evaluated in the clinical study. Results. Estimates of total tendon thickness (r = 0.41, P = 0.31 or percentage of thickness tears (r = 0.67, P = 0.07 using the conventional method did not correlate well with true tendon thickness. Using the intra-articular depth guide, estimates of exposed footprint (r = 0.92, P = 0.001, total tendon thickness (r = 0.96, P = 0.0001, and percentage of tendon thickness torn (r = 0.88, P = 0.004 correlated with true anatomic measurements. Seven of 32 patients had their treatment plan altered based on the measurements made by the intra-articular depth guide. Conclusions. The intra-articular depth guide appeared to better correlate with true anatomic measurements. It may be useful during the evaluation and development of treatment plans for partial thickness articular surface rotator cuff tears.

  5. CT classification of intra-articular calcaneus fractures. CT-Klassifikation intraartikulaerer Kalkaneusfrakturen

    Energy Technology Data Exchange (ETDEWEB)

    Haeberle, H.J. (Abt. fuer Roentgendiagnostik, Zentrum fuer Radiologie, Univ. Ulm (Germany)); Minholz, R.; Bader, C. (Abt. fuer Roentgendiagnostik, Zentrum fuer Radiologie, Univ. Ulm (Germany)); Tomczak, R. (Abt. fuer Roentgendiagnostik, Zentrum fuer Radiologie, Univ. Ulm (Germany)); Rilinger, N. (Abt. fuer Roentgendiagnostik, Zentrum fuer Radiologie, Univ. Ulm (Germany)); Friedrich, J.M. (Abt. fuer Roentgendiagnostik, Zentrum fuer Radiologie, Univ. Ulm (Germany)); Bauer, G. (Abt. fuer Unfallchirurgie, Hand-, Plastische und Wiederherstellungschirurgie, Univ. Ulm (Germany)); Mutschler, W. (Abt. fuer Unfallchirurgie, Hand-, Plastische und Wiederherstellungschirurgie, Univ. Ulm (Germany))

    1993-12-01

    93 patients with 102 intraarticular calcaneus fractures (ICF) were examined by CT from 1986 to 1992. The images were evaluated with the use of a modified classification based on the number of fractured heel bone facets (2 facets in 4.8%, 3 facets in 53.9%, 4 facets in 32.3%, comminution in 8.8% of the fractures), the involvement of the calcaneoucuboid joint (60.8%) and the fracture mechanism (tongue-type in 28.4%, joint depression in 62.7%) with the weight-bearing calcaneal compartments taken into special consideration. In that way, each intraarticular calcaneus fracture could be scored, enabling a fast diagnosis comprising factors relevant for the therapy and prognosis. (orig.)

  6. Surgical treatment of intraarticular fractures of the calcaneus: comparison between flat plate and calcaneal plate

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Almeida da Silva

    Full Text Available ABSTRACT OBJECTIVE: To evaluate the clinical results of surgical treatment of intraarticular fractures of the calcaneus, comparing the use of calcaneal plate and flat plate. METHODS: This was a retrospective study assessing the postoperative results of 25 patients between 2013 and 2015. Patients undergoing surgical treatment of intraarticular fractures of the calcaneus without concomitant surgical lesions were included. Patients who did not complete appropriate follow-up after surgery were excluded from the study. RESULTS: The unavailability of calcaneal plates at resource-limited settings, associated with the availability and lower cost of flat plates, may have been a confounding factor in the present study. However, there was no statistical difference between the outcomes of fractures treated with calcaneal plates or flat plates. CONCLUSION: Statistical inference shows that, when calcaneal plates are not available, it is possible to use flat plates with similar clinical outcomes.

  7. Large Intra-Articular Anterior Cruciate Ligament Ganglion Cyst, Presenting with Inability to Flex the Knee

    Directory of Open Access Journals (Sweden)

    Jake Sloane

    2010-01-01

    Full Text Available A 41-year-old female presented with a 3-month history of gradually worsening anterior knee pain, swelling and inability to flex the knee. Magnetic resonance imaging (MRI revealed a large intra-articular cystic swelling anterior to the anterior cruciate ligament (ACL, extending into the Hoffa's infrapatellar fat pad. Following manipulation under anaesthesia and arthroscopic debridement of the cyst, the patient's symptoms were relieved with restoration of normal knee motion. ACL ganglion cysts are uncommon intra-articular pathological entities, which are usually asymptomatic and diagnosed incidentally by MRI. This is the first reported case of an ACL cyst being so large as to cause a mechanical block to knee flexion.

  8. Anestesia em paciente com insensibilidade congênita a dor e anidrose Anestesia en paciente con insensibilidad congénita al dolor y anhidrosis Anesthesia in a patient with congenital insensitivity to pain and anhidrosis

    Directory of Open Access Journals (Sweden)

    Carlos Rogério Degrandi Oliveira

    2009-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A insensibilidade congênita a dor e anidrose (ICDA ou neuropatia hereditária sensorial e autonômica tipo IV (NHSA tipo IV é neuropatia autossômica recessiva rara do grupo das neuropatias hereditárias sensoriais e autonômicas (NHSA, caracterizada por insensibilidade ao estímulo doloroso, anidrose e retardo mental. Existem poucos relatos sobre a conduta anestésica em pacientes com ICDA devido sua extrema raridade. O objetivo deste relato foi apresentar a conduta anestésica em paciente com ICDA submetida à artrodese de tornozelo esquerdo com colocação de haste e discutir as características de interesse para a anestesia nestes pacientes. RELATO DO CASO: Paciente com história de ICDA foi admitida para artrodese de tornozelo esquerdo devido à artropatia de Charcot. Na sala de operação foi monitorizada com eletrocardiógrafo, índice bispectral, SEF 95%, pressão arterial não invasiva e saturação periférica da hemoglobina, medicada com midazolam como pré-anestésico e submetida à anestesia venosa com propofol e cisatracúrio. Não houve a necessidade de administração de analgésicos. Após intubação traqueal, foi acrescentada monitorização da pressão expiratória final do gás carbônico e da temperatura esofágica. Não apresentou complicações no período perioperatório. Teve alta hospitalar no segundo dia de pós-operatório. CONCLUSÕES: Embora apresentem insensibilidade à dor, alguns pacientes apresentam hiperestesia tátil, o que poderia causar sensações desagradáveis durante a manipulação cirúrgica. Apesar de relatos na literatura de pacientes submetidos a bloqueios no neuroeixo e até mesmo a procedimentos sem anestesia, neste caso utilizou-se a anestesia venosa que proporcionou condições adequadas para o procedimento anestésico-cirúrgico.JUSTIFICATIVA Y OBJETIVOS: La falta de sensibilidad congénita al dolor y la anhidrosis (ICDA o neuropatía hereditaria sensorial y auton

  9. Intra-articular injection of dexketoprofen in rat knee joint : Histopathologic assessment of cartilage & synovium

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    Aycan Guner Ekici

    2014-01-01

    Full Text Available Background & objectives: Effective pain control following outpatient surgical procedures is an important aspect of patient discharge. This study was carried out with an aim to investigate the histopathological effects of intra-articular dexketoprofen trometamol injection in knee joint on synovium and cartilage in an experimental rat model. Methods: In each of 40 rats, the right knee was designated as the study group and the left knee as the control group (NS group. Under aseptic conditions, 35 rats received an injection of 0.25 ml (6.25 mg dexketoprofen trometamol into the right knee joint and an injection of 0.25 ml 0.9 per cent normal saline solution into the left knee joint. On the 1 st , 2 nd , 7 th , 14 th , and 21 st days after intra-articular injection, rats in specified groups were sacrificed by intraperitoneal injection of 120 mg/kg sodium thiopental. Knee joints were separated and sectioned for histopathological examination. Inflammatory changes in the joints were recorded according to a grade scale. Results: No significant difference in terms of pathological changes both in synovium and cartilage was observed between the NS group and the study group on days 1, 2, 7, 14 and 21 after intra-articular injection of dexketoprofen or saline in the knee joint. Interpretation & conclusions: The findings showed no evidence of significant histopathological damage to the cartilage and synovia for a period up to 21 days following intra-articular administration of dexketoprofen trometamol in the knee joints of rats.

  10. Treatment of mallet finger due to intra-articular fracture of the distal phalanx.

    Science.gov (United States)

    Hamas, R S; Horrell, E D; Pierret, G P

    1978-07-01

    When a mallet finger deformity results from an intra-articular fracture of the distal phalanx comprising more than one third of the articular surface, an accurate reduction of this fracture is necessary to prevent secondary degenerative arthritis. A technique for open reduction is described in which the distal interphalangeal joint is exposed by dividing the extensor tendon and permitting a precise reduction of the fracutre fragment. Elective division of the extensor tendon had not compromised the results.

  11. The chondroprotective effects of intraarticular application of statin in osteoarthritis: An experimental study

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    Sarp Bayyurt

    2015-01-01

    Full Text Available Background: Osteoarthritis (OA is the most frequent chronic joint disease causing pain and disability. Recent reports have shown that statin may have the potential to inhibit osteoarthritis. This study of early stage OA developed in an experimental rabbit model, aimed to evaluate the chondroprotective effects of intraarticularly applied atorvastatin on cartilage tissue macroscopically and histopathologically by examining intracellular and extracellular changes by light and electron microscope. Materials and Methods: The experimental knee OA model was created by cutting the anterior cruciate ligament of the 20 mature New Zealand rabbits. The rabbits were randomly allocated into two groups of 10. Study group: The group that received intraarticular statin therapy; Control group: The group that did not receive any intraarticular statin therapy. The control group received an intraarticular administration of saline and the study group atorvastatin from the 1st week postoperatively, once a week for 3 weeks. The knee joints were removed including the femoral and tibial joint surfaces for light and electron microscopic studies of articular cartilages. Results: The mean total points obtained from the evaluation of the lesions that developed in the medial femoral condyle were 11.33 ± 0.667 for the control group and 1.5 ± 0.687 for the study group. The mean total points obtained from the evaluation of the lesions that developed in medial tibial plateau cartilage tissue were 11.56 ± 0.709 for the control group and 1.40 ± 0.618 for the study group. Electron microscopic evaluation revealed healthy cartilage tissue with appropriate chondrocyte and matrix structure in study group and impaired cartilage tissue in control group. Conclusion: Chondroprotective effect of statin on cartilage tissue was determined in this experimental OA model evaluated macroscopically and by light and electron microscope. There are some evidences to believe that the

  12. Biomechanical comparison of orthogonal versus parallel double plating systems in intraarticular distal humerus fractures.

    Science.gov (United States)

    Atalar, Ata C; Tunalı, Onur; Erşen, Ali; Kapıcıoğlu, Mehmet; Sağlam, Yavuz; Demirhan, Mehmet S

    2017-01-01

    In intraarticular distal humerus fractures, internal fixation with double plates is the gold standard treatment. However the optimal plate configuration is not clear in the literature. The aim of this study was to compare the biomechanical stability of the parallel and the orthogonal anatomical locking plating systems in intraarticular distal humerus fractures in artificial humerus models. Intraarticular distal humerus fracture (AO13-C2) with 5 mm metaphyseal defect was created in sixteen artificial humeral models. Models were fixed with either orthogonal or parallel plating systems with locking screws (Acumed elbow plating systems). Both systems were tested for their stiffness with loads in axial compression, varus, valgus, anterior and posterior bending. Then plastic deformation after cyclic loading in posterior bending and load to failure in posterior bending were tested. The failure mechanisms of all the samples were observed. Stiffness values in every direction were not significantly different among the orthogonal and the parallel plating groups. There was no statistical difference between the two groups in plastic deformation values (0.31 mm-0.29 mm) and load to failure tests in posterior bending (372.4 N-379.7 N). In the orthogonal plating system most of the failures occurred due to the proximal shaft fracture, whereas in the parallel plating system failure occurred due to the shift of the most distal screw in proximal fragment. Our study showed that both plating systems had similar biomechanical stabilities when anatomic plates with distal locking screws were used in intraarticular distal humerus fractures in artificial humerus models. Copyright © 2016 Turkish Association of Orthopaedics and Traumatology. Production and hosting by Elsevier B.V. All rights reserved.

  13. A Clinically Realistic Large Animal Model of Intra-Articular Fracture

    Science.gov (United States)

    2013-10-01

    calcaneus to the talus via the tripod pins. The talus is driven into the anterior portion of the tibia causing an intra-articular fracture extending...scans (0.3mm x 0.3mm x 1mm voxels) were acquired prior to fracture (baseline) and 12 weeks after index surgery. The outer cortex of the distal tibia ...posterior epiphyseal bone of the fracture case to the intact surface while temporarily disregarding deviations resulting from the fracture . The

  14. Operative treatment of intra-articular calcaneal fractures with calcaneal plates and its complications

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    Rak Vaclav

    2009-01-01

    Full Text Available Background: In a retrospective study we analysed intra-articular calcaneal fracture treatment by comparing results and complications related to fracture stabilization with nonlocking calcaneal plates and locking compression plates. Materials and Methods: We performed 76 osteosynthesis (67 patients of intra-articular calcaneal fractures using the standard extended lateral approach from February 2004 to October 2007. Forty-two operations using nonlocking calcaneal plates (group A were performed during the first three years, and 34 calcaneal fractures were stabilized using locking compression plates (group B in 2007. In the Sanders type IV fractures, reconstruction of the calcaneal shape was attempted. Depending on the type of late complication, we performed subtalar arthroscopy in six cases, arthroscopically assisted subtalar distraction bone block arthrodesis in six cases, and plate removal with lateral-wall decompression in five cases. The patients were evaluated by the AOFAS Ankle-Hindfoot Scale. Results: Wound healing complications were 7/42 (17% in group A and 1/34 (3% in group B. No patient had deep osseous infection or foot rebound compartment syndrome. Preoperative size of Bφhler´s angle correlated with postoperative clinical results in both groups. There were no late complications necessitating corrective procedure or arthroscopy until December 2008 in Group B. All late complications ccurred in Group A. The overall results according to the AOFAS Ankle Hindfoot Scale were good or excellent in 23/42 (55% in group A and in 30/34 (85% in group B. Conclusion: Open reduction and internal fixation of intra-articular calcaneal fractures has become a standard surgical method. Fewer complications and better results related to treatment with locking compression plates confirmed in comparison to nonlocking ones were noted for all Sanders types of intra-articular calcaneal fractures. Age and Sanders type IV fractures are not considered to be the

  15. Age and Sex Features of Proximal Hip Geometry in Patients with its Intraarticular Fractures

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    N.V. Grygorieva

    2015-10-01

    Full Text Available According to the literature data, some parameters of the femoral bone (FB, namely the length of its axis, head-collum-diaphyseal angle, etc., are independent predictors of proximal femoral (PF fractures, but such studies among Ukrainian patients are absent. This article presents the literature data and the results of own research on the geometrical features of the FB in patients with intra-articular PF fractures. We have analyzed 100 survey (anteroposterior radiographs of the hip joint in patients aged 50–89 years (median age 70.98 ± 0.99 years. We observed 31 women and 39 men, who were hospitalized with intra-articular FB fractures, and 30 persons (16 women and 14 men without fractures. Assessment of hip geometry parameters was performed on the contralateral limb in relation to fracture. For the analysis, patients were divided into subgroups by gender and age. It was established the significant effect of the age on the parameters of PF geometry in men and women with intra-articular fractures, but not in patients without fractures. Also, we have found the significantly lower indices of the length of femoral axis, the base and the diameter of the head, «head — acetabulum» distance in men with intra-articular PF fractures compared to the parameters in persons without fractures, in the absence of significant differences in indices of women. Identified differences should be considered for both planning surgery after PF fracture and for predicting the risk of PF fractures in older age patients.

  16. CT guided percutaneous calcaneoplasty: a case of metastatic intra-articular calcaneus fracture.

    Science.gov (United States)

    Kamalian, S; Hirsch, A E; Growney, M L; Raskin, K A; Yoo, A J; Krag, K J; Hirsch, J A

    2009-12-01

    Symptomatic bone metastases to the calcaneus are rare.1 Minimally invasive percutaneous augmentation is an option in the palliative management of patients with metastatic bone disease, and has been commonly used in the setting of vertebral compression fractures.2 Calcaneal augmentation can potentially allow for earlier weight bearing and a shorter period of disability. A case report is presented of percutaneous intra-articular calcaneal fracture augmentation using polymethyl methacrylate.

  17. Intra-articular membranous interposition detected by MRI in developmental dysplasia of the hip

    International Nuclear Information System (INIS)

    Watanabe, W.; Itoi, Eiji; Sato, Kozo

    2000-01-01

    Intra-articular membranous interposition was detected by MRI in the hip joint with residual subluxation of a girl aged 5 years 10 months. This structure, which had low signal intensity on both T1- and T2-weighted images, separated the femoral head from the acetabulum. Histological examination revealed chondrometaplasia, which suggested that this interposition might be transformed to a surface cartilaginous tissue of the secondary acetabulum often observed in residual subluxation of the hip. (orig.)

  18. Intra-articular membranous interposition detected by MRI in developmental dysplasia of the hip

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, W.; Itoi, Eiji; Sato, Kozo [Akita Univ. (Japan). Dept. of Orthopedic Surgery

    2000-12-01

    Intra-articular membranous interposition was detected by MRI in the hip joint with residual subluxation of a girl aged 5 years 10 months. This structure, which had low signal intensity on both T1- and T2-weighted images, separated the femoral head from the acetabulum. Histological examination revealed chondrometaplasia, which suggested that this interposition might be transformed to a surface cartilaginous tissue of the secondary acetabulum often observed in residual subluxation of the hip. (orig.)

  19. Anestesia venosa total em paciente portador de Osteogênesis imperfecta: relato de caso Anestesia venosa total en paciente portador de Osteogénesis imperfecta: relato de caso Total intravenous anesthesia in Osteogenesis imperfecta patient: case report

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    José Francisco Nunes Pereira das Neves

    2004-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A Osteogênesis Imperfecta é uma doença genética rara do tecido conjuntivo, com prevalência de 1/10000, que primariamente envolve a ossificação endocondral, resultando em ossos frágeis, múltiplas fraturas e deformidades esqueléticas. O objetivo desse artigo foi relatar um caso de paciente portador de Osteogenesis Imperfecta, submetido à anestesia venosa total para tratamento cirúrgico de fratura de fêmur. RELATO DO CASO: Paciente do sexo masculino, 15 anos, 41 kg, 140 cm, com história de Osteogênesis Imperfecta e cardiopatia, programado para tratamento cirúrgico de fratura do fêmur. Na sala de operação foi monitorizado com ECG, FC, PANI e SpO2 e submetido à anestesia geral venosa total com propofol, alfentanil e cisatracúrio. Após IOT, foi acrescentada monitorização da P ET CO2 e da temperatura esofágica. No período intra-operatório e na sala de recuperação pós-anestésica não apresentou complicações. Teve alta hospitalar no 5º dia de pós-operatório. CONCLUSÕES: O presente relato mostrou boa evolução intra e pós-operatória de paciente com Osteogênesis Imperfecta submetido à anestesia geral venosa total. A complexidade da doença mostrou a necessidade de avaliação e monitorização adequada pelo anestesiologista.JUSTIFICATIVA Y OBJETIVOS: La Osteogénesis Imperfecta es una rara enfermedad genética del tejido conjuntivo, con prevalencia de 1/10000, que primariamente envuelve la osificación endocondral, resultando en huesos frágiles, múltiplas fracturas e deformidades esqueléticas. El objetivo de ese artículo fue relatar un caso de paciente portador de Osteogénesis Imperfecta, sometido a anestesia venosa total para tratamiento quirúrgico de fractura de fémur. RELATO DEL CASO: Paciente del sexo masculino, 15 años, 41 kg, 140 cm, con historia de Osteogénesis Imperfecta y cardiopatía, programado para tratamiento quirúrgico de fractura del fémur. En la sala de operaci

  20. Usos do sulfato de magnésio em obstetrícia e em anestesia Usos del sulfato de magnesio en obstetricia y en anestesia Applications of Magnesium Sulfate in Obstetrics and Anesthesia

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    Fabiano Timbó Barbosa

    2010-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O magnésio é um íon predominantemente intracelular. Seu efeito bloqueador do receptor NMDA lhe confere características analgésicas e sedativas. O objetivo desse artigo foi revisar a fisiologia, a farmacologia e a diminuição da concentração plasmática do magnésio, assim como algumas das suas aplicações em obstetrícia e em anestesia. CONTEÚDO: O magnésio é um cátion intracelular que possui múltiplas funções: é cofator de enzimas do metabolismo glicídico e de enzimas da degradação dos ácidos nucleicos, proteínas e ácidos graxos; regula a passagem de íons transmembrana e intervém na atividade de várias enzimas. O paciente em estado crítico apresenta tendência à hipomagnesemia e o tratamento consiste em corrigir a causa quando possível acompanhada da reposição do magnésio. Já foi demonstrada a redução da concentração alveolar m��nima (CAM dos agentes inalatórios em animais e do uso de opioides em humanos sob anestesia. CONCLUSÕES: O sulfato de magnésio vem sendo utilizado em obstetrícia com boa efetividade para inibição do trabalho de parto prematuro e para o tratamento das crises convulsivas associadas ao quadro de eclâmpsia. É um fármaco com potencial analgésico e sedativo que pode ser utilizado como coadjuvante durante a anestesia geral atenuando a resposta pressórica à intubação traqueal e diminuindo a necessidade de anestésicos.JUSTIFICATIVA Y OBJETIVOS: El magnesio es un ión predominantemente intracelular. Su efecto bloqueador del receptor NMDA le confiere características analgésicas y sedativas. El objetivo de este artículo, fue revisar la fisiología, la farmacología y la disminución de la concentración plasmática del magnesio, como también de algunas de sus aplicaciones en obstetricia y en anestesia. CONTENIDO: El magnesio es un catión intracelular que posee múltiples funciones: es cofactor de enzimas del metabolismo glicídico y de enzimas de

  1. Hematoma após anestesia peridural: tratamento conservador. Relato de caso Hematoma posterior a la anestesia peridural: tratamiento conservador. Relato de caso Hematoma after epidural anesthesia: conservative treatment. Case report

    Directory of Open Access Journals (Sweden)

    Edno Magalhães

    2007-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O hematoma associado à compressão espinhal após anestesia peridural é uma complicação neurológica grave, apesar da pequena incidência relatada (1:150.000. É um episódio agudo, e o tratamento tradicionalmente aplicado é a descompressão cirúrgica de urgência. Mais recentemente, em casos específicos, o tratamento com corticosteróide tem sido aplicado como alternativa, com boa recuperação neurológica. O objetivo deste relato foi expor um caso de hematoma peridural com tratamento conservador e recuperação neurológica completa. RELATO DO CASO: Paciente do sexo feminino, 34 anos, estado físico ASA I, sem qualquer histórico de coagulopatia ou terapia anticoagulante, submetida à anestesia peridural com punção única, em L2-L3, para tratamento cirúrgico de varizes nos membros inferiores. Oito horas após a anestesia regional, ela ainda apresentava bloqueio motor completo (escala de Bromage, redução das sensibilidades térmica e dolorosa abaixo do nível L3, hiperalgesia na região plantar esquerda, preservação dos reflexos tendinosos e ausência de dor lombar. A tomografia computadorizada revelou hematoma peridural em L2 com compressão do saco dural. Dez horas após a punção peridural não havia progressão dos sinais e sintomas neurológicos. Optou-se, então, pelo tratamento com metilprednisolona em infusão venosa contínua (5,3 mg.kg-1 na primeira hora e 1,4 mg.kg-1.h-1 nas 23 horas subseqüentes. Oito horas após o início do tratamento, a paciente recuperou as sensibilidades térmica e dolorosa, e houve regressão total do bloqueio motor. Na 12ª hora, deambulava e referia dor na ferida operatória. O hematoma peridural não foi visualizado em nova tomografia computadorizada na 14ª hora após o início do tratamento. A paciente recebeu alta hospitalar 86 horas depois do início do tratamento conservador, sem comprometimento neurológico. Uma tomografia computadorizada de controle, ap

  2. Anestesia em paciente com síndrome de Rubinstein-Taybi: relato de caso Anestesia en paciente con síndrome de Rubinstein-Taybi: relato de caso Anesthesia in patient with Rubinstein-Taybi syndrome: case report

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    Carlos Rogério Degrandi Oliveira

    2005-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A síndrome de Rubinstein-Taybi (SRT é uma doença genética causada por uma mutação ou apagamento do cromossomo 16, caracterizada por retardo físico e mental, anormalidades craniofaciais e hálux e polegares largos. Há pouca informação sobre esta síndrome na literatura anestésica. O objetivo deste relato foi apresentar a conduta anestésica em paciente submetido à cirurgia odontológica e discutir as características de interesse para a anestesia nesses pacientes. RELATO DO CASO: Paciente do sexo masculino, 9 anos, 28 kg, submetido à anestesia geral para extrações de dentes anormalmente posicionados. Apresentava as características típicas da SRT, retardo físico e mental, anormalidades craniofaciais e hálux e polegares largos. A anestesia foi induzida e mantida com sevoflurano, inicialmente sob máscara facial e após intubação nasotraqueal em ventilação assistida manual com sistema de Bain. Não houve intercorrências e a cirurgia foi realizada em regime ambulatorial. CONCLUSÕES: A importância da avaliação pré-anestésica é enfatizada, devido às malformações, inclusive cardíacas, associadas a esta síndrome. Este paciente, em particular, não apresentava comprometimento cardíaco, presente em um terço dos casos. É recomendável preparação para possível dificuldade de manutenção das vias aéreas.JUSTIFICATIVA Y OBJETIVOS: El síndrome de Rubinstein-Taybi (SRT es una enfermedad genética causada por una mutación o apagamiento del cromosoma 16, caracterizada por retardo físico y mental, anormalidades craneofaciales y hálux y pulgares anchos. Hay poca información sobre este síndrome en la literatura anestésica. El objetivo de este relato ha sido en presentar la conducta anestésica en paciente sometido a cirugía odontológica y discutir las características de interés para la anestesia en estos pacientes. RELATO DEL CASO: Paciente del sexo masculino, 9 años, 28 kg, sometido a

  3. The effect of intra-articular Tenoxicam on knee effusion after arthroscopy.

    Science.gov (United States)

    Jawish, Roger; Najdi, Hassan; Abi Safi, Claude; Chameseddine, Ali

    2015-07-01

    NSAIDs and analgesic drugs are used intra-articularly after knee arthroscopy for pain relief. However, synovial effusion is still a common cause of delayed physical therapy. The aim of this study was to demonstrate the beneficial effect of intra-articular injection of Tenoxicam on knee effusion after arthroscopy. This was a prospective non-randomized study on 134 patients with a mean age of 36.7 years. Knee arthroscopy on a day-case basis was performed; normal saline was used for irrigation. At the end of the procedure, fluid was aspirated from the knee joint and 20 ml of Tenoxicam diluted with 20 ml of 0.9% normal saline was injected into the knee five minutes before deflation of limb tourniquet. The same surgeon performed clinical examination for knee effusion 14 days postoperatively. Encountered pathologies included meniscal injury, degenerative arthropathy, synovial plica and ACL rupture. Knee effusion developed in 15.7% of the patients, particularly in those with degenerative arthropathy (p = 0.006) and meniscal lesions (p = 0.06). Intra-articular Tenoxicam is a simple method for the prevention of postoperative knee effusion. Degenerative arthropathy and meniscal lesions are major risk factors for post arthroscopy knee effusion.

  4. Intraarticular Injection of Allogenic Mesenchymal Stem Cells has a Protective Role for the Osteoarthritis.

    Science.gov (United States)

    Yang, Xin; Zhu, Tian-Yue; Wen, Li-Cheng; Cao, Yong-Ping; Liu, Chao; Cui, Yun-Peng; Meng, Zhi-Chao; Liu, Heng

    2015-09-20

    Researchers initially proposed the substitution of apoptotic chondrocytes in the superficial cartilage by injecting mesenchymal stem cells (MSCs) intraarticularly. This effect was termed as bio-resurfacing. Little evidence supporting the treatment of osteoarthritis (OA) by the delivery of a MSC suspension exists. The aim of this study was to investigate the effects of injecting allogenic MSCs intraarticularly in a rat OA model and to evaluate the influence of immobility on the effects of this treatment. We established a rat knee OA model after 4 and 6 weeks and cultured primary bone marrow MSCs. A MSC suspension was injected into the articular space once per week for 3 weeks. A subgroup of knee joints was immobilized for 3 days after each injection, while the remaining joints were nonimmobilized. We used toluidine blue staining, Mankin scores, and TdT-mediated dUTP-biotin nick end labeling staining to evaluate the therapeutic effect of the injections. Comparisons between the therapy side and the control side of the knee joint were made using paired t-test, and comparisons between the immobilized and nonimmobilized subgroups were made using the unpaired t-test. A P value 0.05). Therapy involving the intraarticular injection of allogenic MSCs promoted cartilage repair in a rat arthritis model, and 3-day immobility after injection had little effect on this therapy.

  5. Intraarticular Injection of Allogenic Mesenchymal Stem Cells has a Protective Role for the Osteoarthritis

    Directory of Open Access Journals (Sweden)

    Xin Yang

    2015-01-01

    Full Text Available Background: Researchers initially proposed the substitution of apoptotic chondrocytes in the superficial cartilage by injecting mesenchymal stem cells (MSCs intraarticularly. This effect was termed as bio-resurfacing. Little evidence supporting the treatment of osteoarthritis (OA by the delivery of a MSC suspension exists. The aim of this study was to investigate the effects of injecting allogenic MSCs intraarticularly in a rat OA model and to evaluate the influence of immobility on the effects of this treatment. Methods: We established a rat knee OA model after 4 and 6 weeks and cultured primary bone marrow MSCs. A MSC suspension was injected into the articular space once per week for 3 weeks. A subgroup of knee joints was immobilized for 3 days after each injection, while the remaining joints were nonimmobilized. We used toluidine blue staining, Mankin scores, and TdT-mediated dUTP-biotin nick end labeling staining to evaluate the therapeutic effect of the injections. Comparisons between the therapy side and the control side of the knee joint were made using paired t-test, and comparisons between the immobilized and nonimmobilized subgroups were made using the unpaired t-test. A P value 0.05. Conclusions: Therapy involving the intraarticular injection of allogenic MSCs promoted cartilage repair in a rat arthritis model, and 3-day immobility after injection had little effect on this therapy.

  6. Osteoarthritis prevention through meniscal regeneration induced by intra-articular injection of meniscus stem cells.

    Science.gov (United States)

    Shen, Weiliang; Chen, Jialin; Zhu, Ting; Yin, Zi; Chen, Xiao; Chen, Longkun; Fang, Zhi; Heng, Boon Chin; Ji, Junfeng; Chen, Weishan; Ouyang, Hong-Wei

    2013-07-15

    Meniscus injury is frequently encountered in clinical practice. Current surgical therapy involving partial or complete meniscectomy relieves pain in the short-term but often leads to osteoarthritis (OA) in the long-term. Here, this study aimed to identify and characterize a novel population of meniscus-derived stem cells (MeSCs) and develop a new strategy of articular cartilage protection by intra-articular injection of these cells. The "stemness" and immune properties of MeSCs were investigated in vitro, while the efficacy of intra-articular injection of MeSCs for meniscus regeneration and OA prevention were investigated in vivo at 4, 8, and 12 weeks postsurgery. MeSCs displayed typical stem cell characteristics such as low immunogenicity and even possessed immunosuppressive function. In a rabbit meniscus injury model, transplantation of allogenous MeSCs did not elicit immunological rejection, but promoted neo-tissue formation with better-defined shape and more matured extracellular matrix. In a rabbit experimental OA model, transplantation of MeSCs further protected joint surface cartilage and maintained joint space at 12 weeks postsurgery, whereas extensive joint surface irregularities and joint space stenosis were observed in the control group. This study thus evoked a new strategy for articular cartilage protection and meniscus regeneration by intra-articular injection of MeSCs for patients undergoing meniscectomy.

  7. Mid-term results of calcaneal plating for displaced intraarticular calcaneus fractures.

    Science.gov (United States)

    Gülabi, Deniz; Sarı, Ferdi; Sen, Cengiz; Avcı, Cem Coşkun; Sağlam, Fevzi; Erdem, Mehmet; Bulut, Güven

    2013-03-01

    The radiological and functional results of surgical treatment in intraarticular calcaneal fractures are presented in this study. 27 feet of 26 patients with displaced intraarticular fractures were treated surgically in our clinic between November 2003 and May 2009. Twenty-one patients were male (81%), and 5 were female (19%). The average age was 29.2 (range, 18-61 years) at the time of the surgical treatment. Open reduction internal fixation was performed by using a calcaneal plate. The results were evaluated according to the Maryland foot scores and Creighton-Nebraska scores. The mean follow-up period was 34.4 months (range, 19-85 months). The radiological evaluation was made according to the mean value changes of Böhler and Gissane angles after injury and at the last follow-up. Except for 3 patients with Sanders type 4 fractures, good results were obtained with surgical treatment. We conclude that open reduction and internal fixation methods yield a reasonable outcome, even in patients with Sanders type 4 intraarticular fractures of the calcaneus.

  8. Intra-articular hyaluronic acid vs platelet-rich plasma in the treatment of hip osteoarthritis.

    Science.gov (United States)

    Di Sante, Luca; Villani, Ciro; Santilli, Valter; Valeo, Massimo; Bologna, Emmalisa; Imparato, Luca; Paoloni, Marco; Iagnocco, Annamaria

    2016-12-05

    To compare the efficacy of ultrasound-guided intra-articular (IA) treatment with platelet-rich plasma (PRP) versus viscosupplementation (hyaluronic acid HA) in hip osteoarthritis. METHODS: A total of 43 patients affected by monolateral severe hip osteoarthritis (OA) were included in the study. Patients were randomized to receive either intra-articular PRP (3 ml) or HA (30 mg/2 ml; 1,000-2,900 kDa), 3 injections in total - 1/week. Clinical assessments for each patient were made at baseline (T0), 4 (T1), and 16 weeks (T2) of follow-up. The primary efficacy outcome was pain reduction as measured by VAS and by WOMAC pain subscale. Data analysis revealed that, compared to T0, in the PRP-treated group VAS scores significantly decreased at T1 but not at T2, thereby indicating an early effect on pain which was not maintained at a longer term follow-up. In the HA group a significant decrease of both VAS and WOMAC values was registered only between T0 and T2. Intra-articular PRP had an immediate effect on pain that was not maintained at longer term follow-up when, on the contrary, the effects of intra-articular HA were evident.

  9. Intra-Articular Corticosteroids in Addition to Exercise for Reducing Pain Sensitivity in Knee Osteoarthritis

    DEFF Research Database (Denmark)

    Soriano-Maldonado, Alberto; Klokker, Louise; Bartholdy, Cecilie

    2016-01-01

    OBJECTIVE: To assess the effects of one intra-articular corticosteroid injection two weeks prior to an exercise-based intervention program for reducing pain sensitivity in patients with knee osteoarthritis (OA). DESIGN: Randomized, masked, parallel, placebo-controlled trial involving 100 particip......OBJECTIVE: To assess the effects of one intra-articular corticosteroid injection two weeks prior to an exercise-based intervention program for reducing pain sensitivity in patients with knee osteoarthritis (OA). DESIGN: Randomized, masked, parallel, placebo-controlled trial involving 100...... the injections all participants undertook a 12-week supervised exercise program. Main outcomes were changes from baseline in pressure-pain sensitivity (pressure-pain threshold [PPT] and temporal summation [TS]) assessed using cuff pressure algometry on the calf. These were exploratory outcomes from a randomized....... The mean group difference in changes from baseline at week 14 was 0.6 kPa (95% CI: -1.7 to 2.8; P = 0.626) for PPT and 384 mm×sec (95% CI: -2980 to 3750; P = 0.821) for TS. CONCLUSIONS: These results suggest that adding intra-articular corticosteroid injection 2 weeks prior to an exercise program does...

  10. Conservative treatment of intra-articular distal phalanx fractures in horses not used for racing.

    Science.gov (United States)

    Ohlsson, J; Jansson, N

    2005-04-01

    To determine the success rate and whether specific patient and treatment factors influenced the outcome after conservative treatment with a bar shoe with quarter clips of intra-articular fractures of the distal phalanx in horses not used for racing. Retrospective study. Thirty-two client-owned horses. Hospital records of horses that had been treated conservatively for intra-articular fractures of the distal phalanx at Skara Equine Hospital or Halland Animal Hospital in Sweden between 1995 and 2001 were reviewed. Racehorses in active training and horses affected with other musculoskeletal diseases were excluded from the study. Follow-up was performed by questionnaire and telephone inquires to the owners 1 to 7 years after injury. Twenty-two horses (69%) returned to their previous or expected level of use and did not wear their bar shoe when they were put back into training. There was no statistically significant correlation between outcome and patient or treatment variables, or bony union of the fracture. Conservative treatment of intra-articular fractures of the distal phalanx carries a fair prognosis for return to previous or expected level of use in horses not used for racing. Radiographic evidence of fracture healing and age of the patient do not seem to influence the prognosis. Horses not used for racing do not need to be shod with a bar shoe with quarter clips for the rest of their athletic career.

  11. Intra-articular (IA) ropivacaine microparticle suspensions reduce pain, inflammation, cytokine, and substance p levels significantly more than oral or IA celecoxib in a rat model of arthritis.

    Science.gov (United States)

    Rabinow, Barrett; Werling, Jane; Bendele, Alison; Gass, Jerome; Bogseth, Roy; Balla, Kelly; Valaitis, Paul; Hutchcraft, Audrey; Graham, Sabine

    2015-02-01

    Current therapeutic treatment options for osteoarthritis entail significant safety concerns. A novel ropivacaine crystalline microsuspension for bolus intra-articular (IA) delivery was thus developed and studied in a peptidoglycan polysaccharide (PGPS)-induced ankle swelling rat model. Compared with celecoxib controls, both oral and IA, ropivacaine IA treatment resulted in a significant reduction of pain upon successive PGPS reactivation, as demonstrated in two different pain models, gait analysis and incapacitance testing. The reduction in pain was attended by a significant reduction in histological inflammation, which in turn was accompanied by significant reductions in the cytokines IL-18 and IL-1β. This may have been due to inhibition of substance P, which was also significantly reduced. Pharmacokinetic analysis indicated that the analgesic effects outlasted measurable ropivacaine levels in either blood or tissue. The results are discussed in the context of pharmacologic mechanisms both of local anesthetics as well as inflammatory arthritis.

  12. ¿QUà HACEMOS LOS ANESTESIÃLOGOS? DESDE LA VIGILANCIA ANESTÃSICA MONITORIZADA HASTA LA ANESTESIA GENERAL

    OpenAIRE

    Ricardo Bustamante, Dr.

    2017-01-01

    RESUMEN: La anestesiología es la rama de la medicina dedicada al alivio del dolor y al total cuidado del paciente antes, durante y después de un acto quirúrgico. Es una de las especialidades de la medicina que más ha avanzado en los últimos 40 años. Es así que hoy se operan pacientes que nunca se hubiera pensado que podrán operarse, llegando a cifras de mortalidad por causa anestésica bajísimas.Los anestesiólogos administran diferentes tipos de anestesia: desde la vigilancia del pa...

  13. Anestesia venosa total em regime de infusão alvo-controlada: uma análise evolutiva

    OpenAIRE

    Nora,Fernando Squeff

    2008-01-01

    JUSTIFICATIVA E OBJETIVOS: A anestesia venosa total (AVT) sofreu diversos avanços desde o início da utilização da técnica. Desde a síntese dos primeiros anestésicos venosos, com a introdução dos barbitúricos (1921) e do tiopental (1934), a AVT evoluiu até o desenvolvimento da AVT com auxílio de bombas com infusão alvo-controlada (IAC). O primeiro modelo farmacocinético para uso em IAC foi descrito por Schwilden em 1981. Foi demonstrado, a partir daí, que era possível manter a concentração pla...

  14. Intra-articular temperatures of the knee in sports – An in-vivo study of jogging and alpine skiing

    Science.gov (United States)

    Becher, Christoph; Springer, Jan; Feil, Sven; Cerulli, Guiliano; Paessler, Hans H

    2008-01-01

    Background Up to date, no information exists about the intra-articular temperature changes of the knee related to activity and ambient temperature. Methods In 6 healthy males, a probe for intra-articular measurement was inserted into the notch of the right knee. Each subject was jogging on a treadmill in a closed room at 19°C room temperature and skiing in a ski resort at -3°C outside temperature for 60 minutes. In both conditions, temperatures were measured every fifteen minutes intra-articulary and at the skin surface of the knee. A possible influence on joint function and laxity was evaluated before and after activity. Statistical analysis of intra-articular and skin temperatures was done using nonparametric Wilcoxon's sign rank sum test and Mann-Whitney's-U-Test. Results Median intra-articular temperatures increased from 31.4°C before activity by 2.1°C, 4°C, 5.8°C and 6.1°C after 15, 30, 45 and 60 min of jogging (all p ≤ 0.05). Median intra-articular temperatures dropped from 32.2°C before activity by 0.5°C, 1.9°C, 3.6°C and 1.1°C after 15, 30, 45 and 60 min of skiing (all n.s.). After 60 minutes of skiing (jogging), the median intra-articular temperature was 19.6% (8.7%) higher than the skin surface temperature at the knee. Joint function and laxity appeared not to be different before and after activity within both groups. Conclusion This study demonstrates different changes of intra-articular and skin temperatures during sports in jogging and alpine skiing and suggests that changes are related to activity and ambient temperature. PMID:18405365

  15. Intra-articular temperatures of the knee in sports – An in-vivo study of jogging and alpine skiing

    Directory of Open Access Journals (Sweden)

    Cerulli Guiliano

    2008-04-01

    Full Text Available Abstract Background Up to date, no information exists about the intra-articular temperature changes of the knee related to activity and ambient temperature. Methods In 6 healthy males, a probe for intra-articular measurement was inserted into the notch of the right knee. Each subject was jogging on a treadmill in a closed room at 19°C room temperature and skiing in a ski resort at -3°C outside temperature for 60 minutes. In both conditions, temperatures were measured every fifteen minutes intra-articulary and at the skin surface of the knee. A possible influence on joint function and laxity was evaluated before and after activity. Statistical analysis of intra-articular and skin temperatures was done using nonparametric Wilcoxon's sign rank sum test and Mann-Whitney's-U-Test. Results Median intra-articular temperatures increased from 31.4°C before activity by 2.1°C, 4°C, 5.8°C and 6.1°C after 15, 30, 45 and 60 min of jogging (all p ≤ 0.05. Median intra-articular temperatures dropped from 32.2°C before activity by 0.5°C, 1.9°C, 3.6°C and 1.1°C after 15, 30, 45 and 60 min of skiing (all n.s.. After 60 minutes of skiing (jogging, the median intra-articular temperature was 19.6% (8.7% higher than the skin surface temperature at the knee. Joint function and laxity appeared not to be different before and after activity within both groups. Conclusion This study demonstrates different changes of intra-articular and skin temperatures during sports in jogging and alpine skiing and suggests that changes are related to activity and ambient temperature.

  16. OUTCOME OF FRACTURE OF INTRAARTICULAR DISTAL FEMUR TREATED WITH DISTAL FEMUR LOCKING COMPRESSION PLATE

    Directory of Open Access Journals (Sweden)

    Swapna Pran Saikia

    2017-10-01

    Full Text Available BACKGROUND The most challenging fractures faced by orthopaedic surgeons are the distal fractures of femur, especially the intraarticular distal femoral fractures. These fractures have been classified according to Orthopaedic Trauma Association (OTA 33-C3. Distal femoral fractures account to 4-7% of all femoral fractures and are less common compared to hip fractures. The aim of the study is to study the functional outcome of fracture of intraarticular distal femur treated with distal femur locking compression plate. MATERIALS AND METHODS This study is a prospective study, which comprised of 30 patients of intraarticular distal femur fracture AO classification 33-C3 who were treated by locking compression plate at Jorhat Medical College and Hospital, Jorhat, Assam. This study was conducted during February 2015 to April 2017. The functional outcome was studied using Neer’s score, outcome of radiology and complication with fracture fixation using LCP. RESULTS Out of 30 patients, 22 were males (73.3% and 8 were females (26.7%. 18 patients had fracture right hand side and 12 patients had left-handed fractures. A 19 years old was the youngest patient and 72 years was the oldest patient. About 70% patients had sustained road traffic accidents and 10% had sustained fall from a height. Four days was the average trauma to operative interval, 22 patients were operated extensile lateral approach and 8 patients were operated by swashbuckler approach. 12 weeks was the average weightbearing duration, 21 weeks was average time for fracture healing. 10 patients had C1 (33.3%, 12 patients had C2 (40% and 8 patients had C3 (26.7% type of fracture according to AO classification. Among 30 patients, 13 patients have shown excellent results, 7 patients have good results, 5 fair results and 5 poor results. Primary bone grafting was done in 4 patients for severely comminuted type C3 fracture. Secondary bone grafting was done in 2 patients who had delayed union at 4

  17. MRI features of three paediatric intra-articular synovial lesions: a comparative study

    Energy Technology Data Exchange (ETDEWEB)

    Kan, J.H. [Monroe Carell Jr. Children' s Hospital at Vanderbilt, Nashville, TN (United States)], E-mail: herman.kan@vanderbilt.edu; Hernanz-Schulman, M. [Monroe Carell Jr. Children' s Hospital at Vanderbilt, Nashville, TN (United States); Damon, B.M.; Yu, Chang [Vanderbilt University, Nashville, TN (United States); Connolly, S.A. [Boston Children' s Hospital, Boston, IL (United States)

    2008-07-15

    Aim: To determine reliable magnetic resonance imaging (MRI) features differentiating three paediatric intra-articular congenital or neoplastic synovial lesions that contain blood products, from post-traumatic or haemorrhagic inflammatory processes. Materials and methods: This was a retrospective review of MRI findings of 22 paediatric intra-articular congenital or neoplastic synovial lesions, including venous malformation (VM) (n = 12), pigmented villonodular synovitis (PVNS; n = 8), and synovial sarcoma (SS; n = 2). These MRI features were compared with 22 paediatric post-traumatic or inflammatory intra-articular processes containing blood products and producing mass effect. The following imaging features were assessed: presence of a discrete mass, extension, extra-articular oedema, susceptibility, joint effusion, and size. Fisher's exact test was used and results were considered statistically significant when p < 0.05. Results: The three intra-articular synovial lesions, compared with controls, were more likely to directly invade osseous structures when a discrete mass was present (13/16, 81.3% versus 1/9, 11.1%; p < 0.002) and extend into extra-articular soft tissues (13/21, 61.9% versus 2/17, 11.8%; p < 0.003), but were less likely to show extra-articular oedema (3/22, 13.6% versus 13/22, 59.1%; p < 0.004), a joint effusion (10/22,45.5% versus 19/22, 86.4%, p < 0.01), susceptibility within a joint effusion (0/22, 0% versus 11/22, 40.9%; p = 0.00), osseous oedema (3/16, 18.8% versus 7/9, 77.8%; p < 0.009), and synovial enhancement (8/21, 38.1% versus 14/16, 87.5%; p < 0.003). VMs had characteristic tubular vessels with internal fluid-fluid levels (11/12) that extended into bone (10/12) and extracapsular soft tissues (11/12). Conclusion: Our study indicates that, despite the overlapping presence of haemorrhagic products, intra-articular VM, PVNS, and SS show MRI features that permit distinction from acquired post-traumatic and haemorrhagic inflammatory

  18. Anestesia peridural contínua com ropivacaína a 0,2% associada a anestesia geral para cirurgia do abdômen superior em crianças Anestesia peridural contínua con ropivacaína a 0,2% asociada a anestesia general para cirugía del abdomen superior en niños Continuous epidural anesthesia with 0.2% ropivacaine associated to general anesthesia for upper abdominal surgery in children

    Directory of Open Access Journals (Sweden)

    Jyrson Guilherme Klamt

    2003-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Técnicas anestésicas têm sido empregadas em pacientes pediátricos para vários tipos de cirurgias, apresentando entre outras vantagens, a analgesia pós-operatória. O objetivo deste estudo foi avaliar o ritmo de infusão de propofol e a recuperação pós-anestésica de crianças submetidas à cirurgia abdominal alta sob anestesia peridural torácica com ropivacaína a 0,2%, associada à anestesia geral com propofol ou propofol mais sufentanil. MÉTODO: Vinte e seis crianças ASA I, II e III, com idades entre 0 e 4 anos, submetidas à cirurgia abdominal alta foram selecionadas para anestesia peridural torácica (T7-T8 com ropivacaína a 0,2% (1,5 ml.kg-1. Foram divididas aleatoriamente em dois grupos: Propofol (infusão de propofol e Sufentanil (infusão de propofol mais sufentanil 1 µg.kg-1. Os ritmos de infusões de propofol foram de 20 e 10 mg.kg-1.h-1 nos grupos Propofol e Sufentanil, respectivamente, ajustadas de modo a manter a pressão arterial cerca de 20% dos valores pré-indução e interrompidas 10 a 15 minutos antes do final estimado da cirurgia. A recuperação pós-anestésica foi avaliada através de uma escala modificada de Aldrete-Kroulik e a sedação avaliada através de uma escala de 5 pontos. RESULTADOS: Duas crianças de cada grupo foram excluídas por problemas técnicos. O ritmo de infusão foi significativamente menor no grupo Sufentanil em relação ao grupo Propofol durante 100 minutos após o início da cirurgia. Os tempos para extubação e transferência para a sala de recuperação pós-anestésica (SRPA foram significativamente menores no grupo Propofol, porém a intensidade e a duração da sedação foram maiores nesse grupo em relação ao grupo Sufentanil. Os escores de recuperação foram similares nos dois grupos. Após 3 horas na SRPA, todos pacientes haviam atingido os critérios para transferência para as enfermarias. Hipotensão arterial transitória foi observada em 2

  19. Anestesia em paciente portador de deficiência de glicose-6-fosfato-desidrogenase: relato de caso Anestesia en paciente portador de deficiencia de glicosa-6-fosfato-desidrogenasa: relato de caso Anesthesia in glucose 6-phosphate dehydrogenase-deficient patient: case report

    Directory of Open Access Journals (Sweden)

    Múcio Paranhos de Abreu

    2002-11-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A Deficiência de Glicose-6-Fosfato-Desidrogenase (G6PD é uma enzimopatia relativamente comum, mas as publicações relacionando essa condição com a anestesia são escassas. O objetivo deste relato é apresentar um caso de paciente portador de Deficiência de G6PD, submetido à tenotomia para alongamento de tendão de Aquiles, sob anestesia venosa associada à bloqueio subaracnóideo. Relato do caso: Paciente masculino, 9 anos, 48 kg, portador de deficiência de G6PD e polineuropatia periférica, submetido à tenotomia de tendão de Aquiles, sob anestesia geral venosa com midazolam, propofol e fentanil , associada à bloqueio subaracnóideo com bupivacaína hiperbárica a 0,5%. Ao final da cirurgia o paciente despertou tranqüilo, sem dor ou outras queixas, evoluiu bem, recebendo alta hospitalar sem intercorrências. CONCLUSÕES: Pela evolução do caso relatado, a anestesia subaracnóidea com bupivacaína associada à anestesia venosa total com propofol, mostrou ser uma técnica segura em pacientes portador de deficiência de G6PD.JUSTIFICATIVA Y OBJETIVOS: - La Deficiencia de Glucosa-6-Fosfato-Desidrogenasa (G6PD es una enzimopatia relativamente común, más las publicaciones relacionando esa condición con la anestesia son escasas. El objetivo de este relato es presentar un caso de un paciente portador de Deficiencia de G6PD, sometido a tenotomia para alongamiento de tendón de Aquiles, bajo anestesia venosa asociada al bloqueo subaracnóideo. RELATO DEL CASO: Paciente masculino, 9 años, 48 kg, portador de deficiencia de G6PD y polineuropatia periférica, sometido a tenotomia de tendón de Aquiles, bajo anestesia general venosa con midazolam, propofol y fentanil asociada a bloqueo subaracnóideo con bupivacaína hiperbárica a 0,5%. Al final de la cirugía el paciente despertó tranquilo, sin dolor u otras quejas, evoluyó bien, recibiendo alta hospitalar sin interocurrencias. CONCLUSIONES: Por la evolución del

  20. Influência da anestesia geral e bloqueio peribulbar em trabeculectomias: comparação visual e pressórica

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    Carlos Buhler

    2012-04-01

    Full Text Available OBJETIVO: Avaliar os resultados de trabeculectomias (TRECs com anestesia geral e bloqueio peribulbar, visando definir de forma indireta a influência das técnicas anestésicas no resultado da cirurgia. MÉTODOS: Foram analisados os prontuários de 25 pacientes com glaucoma não controlado submetidos à trabeculectomia (TREC, sendo 11 com anestesia geral e 14 com anestesia peribulbar. Foram incluídos somente pacientes pseudofácicos com glaucoma e sem outras patologias oculares como retinopatia diabética ou doença macular relacionada a idade. A acuidade visual (AV, pressão intraocultar (PIO, número de medicações utilizadas, além de dados demográficos foram coletados retrospectivamente com 7, 30, 6 meses e 1 ano de pós-operatório. RESULTADOS: Ambos os grupos foram semelhantes nos quesitos demográficos, onde não houve diferença estatisticamente significante entre idade, sexo e raça. Não foram encontradas diferenças significativas nas variáveis estudadas em todas as avaliações, com significância estatística (p<0,05. CONCLUSÃO: Não encontramos diferenças entre os resultados de TRECs com anestesia geral e com bloqueio peribulbar, porém mais estudos com um número maior de pacientes são necessários para comprovar este achado.

  1. Procedimientos de asistencia odontológica hospitalaria en pacientes discapacitados psíquicos no colaboradores tratados con anestesia general

    OpenAIRE

    Hernán Pérez de la Ossa, Tomás

    2016-01-01

    La literatura existente acerca del manejo odontológico de pacientes discapacitados es escasa. El tratamiento de estos pacientes se realiza frecuentemente bajo anestesia general y en un medio hospitalario. La población de discapacitados psíquicos representa un grupo con una alta incidencia de patologías orales. La falta de diagnostico y las diferencias en el tratamiento contribuyen al empeoramiento de su salud oral y justifica la existencia de unidades especificas para estos pacientes...

  2. Bupivacaína racêmica, levobupivacaína e ropivacaína em anestesia loco-regional para oftalmologia: um estudo comparativo Racemic bupivacaine, levobupi vacaine and ropivacaine in regional anesthesia for ophtalmology: a comparative study

    Directory of Open Access Journals (Sweden)

    Edno Magalhães

    2004-04-01

    Full Text Available OBJETIVO: A bupivacaína racêmica, utilizada largamente em anestesia peribulbar devido à boa qualidade de bloqueio motor, apresenta menor margem de segurança para cardiotoxicidade em relação a ropivacaína e bupivacaína levógira. O objetivo deste estudo foi comparar o grau de bloqueio motor e alteração da pressão intra-ocular (PIO em anestesia peribulbar produzida pela bupivacaína racêmica, levobupivacaína e ropivacaína. MÉTODOS: Noventa e sete pacientes, estado físico I e II da classificação da Sociedade Americana de Anestesiologistas, submetidos a anestesia peribulbar, foram divididos em três grupos: grupo A-(n=16 bupivacaína racêmica 0,75% com adrenalina 1:200.000; grupo B -(n=16 bupivacaína levógira 0,75% com adrenalina 1:200.000; grupo C -(n=15 ropivacaína 0,75%. Utilizou-se 7ml da solução anestésica com 280 UI de hialuronidase, em punção única no rebordo orbital inferior. Foram registrados a PIO e grau de bloqueio motor 5 minutos antes da punção e 1, 2, 3, 4, 5 e 10 minutos após a punção. O bloqueio motor foi avaliado pela escala de Nicoll. Para a análise estatística, foram utilizados os testes de Wilcoxon, análise de freqüência simples e t de Student. Foi considerado significativo pBACKGROUND AND OBJECTIVE: Racemic bupivacaine, used in peribulbar anesthesia owing to its high potential to promote motor blockade, presents a smaller safety margin for cardiotoxicity in relation to ropivacaine and levobupivacaine. The objective of this study was to compare the degree of motor blockade and alteration of intraocular pressure (IOP produced by racemic bupivacaine, levobupivacaine and ropivacaine in peribulbar block. METHOD: Ninety seven patients, ASA physical status I and II, submitted to peribulbar anesthesia, were randomly allocated into three groups: group A-(n=16 receiving racemic bupivacaine 0.75% with epinephrine 1:200.000; group B -(n=16 levobupivacaine 0.75% with epinephrine 1:200.000; group C -(n=15

  3. Concentração plasmática de ropivacaína durante anestesia peridural lombar em crianças

    Directory of Open Access Journals (Sweden)

    Verônica Vieira da Costa

    2002-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A ropivacaína é o mais novo anestésico local de uso na prática clínica. Sua estrutura é semelhante a forma levógira da bupivacaína, tendo portanto baixa toxicidade. Os valores das concentrações plasmáticas que podem ser atingidos em crianças, com o uso desta droga e também da bupivacaína (mesmo a forma racêmica administradas por via peridural lombar, são ainda pouco conhecidos. O objetivo desse estudo foi avaliar as concentrações sangüíneas de ropivacaína e bupivacaína por via peridural lombar em crianças, em bloqueios eficientes, relacionando-as aos valores descritos como níveis plasmáticos seguros. MÉTODO: Oitenta e um pacientes de ambos os sexos, submetidos à cirurgia de membros inferiores, receberam aleatoriamente ropivacaína (n = 41 ou bupivacaína (n = 40 por via peridural lombar associado à anestesia geral. Foram coletadas oito amostras de sangue venoso nos intervalos de tempo: zero (controle, 5, 25, 40, 60, 120, 180 e 240 minutos, e através de cromatografia de gás foram dosadas as concentrações plasmáticas da ropivacaína e da bupivacaína. RESULTADOS: Não houve diferença estatisticamente significante com relação aos dados antropométricos e variáveis fisiológicas estudadas entre os pacientes que receberam ropivacaína e bupivacaína. As doses médias administradas de ropivacaína e bupivacaína foram 2,35 mg.kg-1 e 2,13 mg.kg-1, respectivamente, que geraram as concentrações plasmáticas de 2,334 µg.ml-1 e 1,111 µg.ml-1, aos 25 e 40 minutos. Ambas abaixo do nível considerado seguro (3 µg.kg-1. CONCLUSÕES: A administração peridural lombar de ropivacaína e bupivacaína em crianças, nas doses abaixo de 3 mg.kg-1, produz bloqueio anestésico eficaz e determina concentrações plasmáticas que podem ser consideradas seguras.

  4. Anestesia em paciente portador de distrofia muscular de Duchenne: relato de casos Anestesia en un paciente portador de distrofia muscular de Duchenne: relato de casos Anesthesia for Duchenne muscular dystrophy patients: case reports

    Directory of Open Access Journals (Sweden)

    Rodrigo Machado Saldanha

    2005-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Este estudo objetiva relatar dois casos de anestesia em pacientes portadores de Distrofia Muscular de Duchenne (DMD, uma doença rara, progressiva e incapacitante, e discutir sobre a conduta anestésica. O comprometimento das funções pulmonar e cardíaca, a possibilidade de ocorrência de hipertermia maligna, a maior sensibilidade aos bloqueadores neuromusculares e o aumento da morbidade pós-operatória são alguns dos desafios enfrentados pelo anestesiologista. RELATO DOS CASOS: O primeiro caso foi o de um paciente pediátrico com diagnóstico de DMD e rabdomiossarcoma, agendado para exérese da lesão e esvaziamento cervical ampliado. Na avaliação pré-anestésica (anamnese, exame clínico e exames complementares não foram detectadas alterações, exceto pela tumoração cervical. Optou-se pela técnica venosa total, com remifentanil em infusão contínua e propofol em infusão alvo-controlada, sem a utilização de bloqueadores neuromusculares. O procedimento cirúrgico teve duração de 180 minutos, sem intercorrências. O segundo caso foi de um paciente do sexo masculino, 24 anos, com diagnóstico de DMD e colelitíase com indicação cirúrgica, cuja avaliação pré-operatória revelou pneumopatia restritiva grave, com diminuições da capacidade e da reserva respiratórias, sendo necessário o uso de BIPAP nasal noturno. Neste paciente, optou-se pela intubação traqueal com sedação mínima e anestesia tópica, seguida pela técnica venosa total com remifentanil em infusão contínua e propofol em infusão alvo-controlada, sem a utilização de bloqueadores neuromusculares. Ao término, o paciente foi extubado ainda na sala de operações e imediatamente colocado no BIPAP nasal. Encaminhado à UTI, com alta no 2º PO e alta hospitalar no 3º PO. CONCLUSÕES: A anestesia venosa total com infusão contínua de propofol e remifentanil sem bloqueadores neuromusculares constitui-se em opção segura e

  5. SAFETY AND EFFECTIVENESS OF INTRAARTICULAR ADMINISTRATION OF ADIPOSE-DERIVED STROMAL VASCULAR FRACTION FOR TREATMENT OF KNEE ARTICULAR CARTILAGE DEGENERATIVE DAMAGE: PRELIMINARY RESULTS OF A CLINICAL TRIAL

    Directory of Open Access Journals (Sweden)

    I. A. Smyshlyaev

    2017-01-01

    Full Text Available The incidence of knee osteoarthritis tends to increase every year and constitutes more than 83% of overall OA morbidity. Moreover, the OA morbidity among younger patients is also increasing. However, currently available treatment methods do not provide quite satisfactory outcomes.Purpose of the study – to evaluate safety and efficacy of intraarticular introduction of autologous adipose-derived stromal vascular fraction for treatment of knee osteoarthritis.Material and methods. By the moment of writing the present report, 28 patients were included into the study. All patients underwent tumescent liposuction under local anesthesia. The stromal vascular fraction was isolated from lipoaspirate within 1,5 hours after harvesting and subsequently injected into the articular cavity. Follow-up period was 6 months after injections. The authors report on efficacy data of 10 patients who completed the study according to protocol and safety data of all 28 patients. Efficacy was evaluated basing on laboratory assessments and patient’s subjective assessment by validated questionnaires.Results. Neither adverse reactions no adverse events were observed. Significant decrease of pain severity by VAS was noted in one week after injection and pain score continued decreasing during the whole follow up period. The increase of KOOS score was noted starting on the fifth week after injection. KSS part 1 score increased in 8 weeks, KSS part 2 score — in 6 months after injection. Physical health, assessed with SF-36 questionnaire significantly improved in 2 and 6 months after the procedure. There was a clear trend towards improvement of mental health.Conclusion. Preliminary results of clinical study suggest intraarticular injection of autologous adipose-derived stromal vascular fraction to be a safe and efficient method of the treatment of knee osteoarthritis. 

  6. Anestesia congênita de córnea associada à anestesia de ramo do trigêmio: relato de caso Congenital corneal anesthesia related to trigeminal anesthesia: case report

    Directory of Open Access Journals (Sweden)

    Miguel José Calix Netto

    2005-12-01

    Full Text Available A anestesia corneana por ser uma condição rara, freqüentemente é confundida ou não diagnosticada durante o exame de rotina do segmento anterior. Relato de caso de um paciente de 18 anos encaminhado ao ambulatório de córnea e doenças externas com quadro clinico de síndrome de olho seco e com diagnóstico provável de síndrome de Sjögren. Era amblíope de olho direito devido à opacidade corneana no eixo visual secundária a trauma com unha na infância. Foi pesquisada sensibilidade corneana que era ausente em ambos os olhos; olho seco grave e com BUT (tempo de quebra do filme lacrimal menor que 4 segundos. Foi feito diagnóstico de anestesia corneana congênita associada a hipoestesia do nervo trigêmio pela avaliação neurológica da sensibilidade facial e movimentos bruscos do queixo que evidenciavam alterações sensoriais do nervo. O oftalmologista geral e principalmente o especialista em segmento anterior devem ter como rotina a pesquisa da sensibilidade corneana no exame do segmento anterior.Corneal anesthesia is a rare condition, therefore its diagnosis is frequently impaired or it is not noticed during the anterior segment examination. Case report of a 18-year-old patient referred to our Corneal and External Disease Department who complained of dry eye symptoms and with a suspicion of Sjögren's syndrome. She had amblyopia of the right eye, consequence of corneal leucoma over the visual axis secondary to a fingernail traumatism inflicted by herself in childhood. On the ophthalmologic examination corneal sensitivity was absent in both eyes. Severe dry eye and breakup time less than four seconds. Diagnosis of congenital corneal anesthesia was established, secondary to trigeminal anesthesia found on neurological evaluation of facial sensitivity. She also showed sudden movements of the chin which evidenced sensorial pathology of the trigeminal nerve. The general ophthalmologist and specially anterior segment specialists must

  7. Anestesia para correção intra-útero de mielomeningocele: relato de caso Anestesia para corrección intra-útero de mielomeningocele: relato de caso Anesthesia for intrauterine myelomeningocele correction: case report

    Directory of Open Access Journals (Sweden)

    Angélica de Fátima de Assunção Braga

    2005-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A cirurgia fetal constitui tratamento de malformações no período pré-natal, que não são adequadamente corrigidas após o nascimento e tem como objetivo tratar ou evitar a progressão das anomalias. O objetivo deste relato é apresentar um caso de anestesia para correção intra-útero de mielomeningocele. RELATO DO CASO: Paciente com 19 anos, 23 semanas de idade gestacional, sem antecedentes anestésicos, estado físico ASA I, submetida à cirurgia fetal intra-uterina, sob anestesia geral associada à peridural contínua. No pré-operatório utilizaram-se indometacina (50 mg por via retal, metoclopramida (10 mg por via venosa, cimetidina (50 mg por via venosa, e como medicação pré-anestésica midazolam (2 mg por via venosa. No espaço peridural injetou-se bupivacaína a 0,25% com adrenalina (25 mg associada à fentanil (100 µg, seguida de passagem de cateter cefálico, para analgesia pós-operatória. O útero foi mantido deslocado para esquerda com auxílio da cunha de Crawford. Indução anestésica em seqüência rápida, com fentanil, propofol e rocurônio e manutenção com isoflurano em concentração de 2,5% a 3% veiculado em O2 e N2O (50%. Após histerotomia, realizada com staplin (grampeadores para promover hemostasia, a região fetal a ser operada foi exposta e a analgesia e imobilidade fetal, foram obtidas com a associação fentanil (10 µg.kg-1 e pancurônio (0,1 mg.kg-1 administrada na região glútea fetal. A pressão arterial sistólica materna foi mantida acima de 100 mmHg, com efedrina em bolus (5 mg, colóides e cristalóides. O líquido amniótico perdido foi substituído por solução fisiológica aquecida. Após correção do defeito fetal, procedeu-se ao fechamento uterino e da membrana amniótica em dois planos, com fio de vicryl e cola de fibrina. Seguiu-se a diminuição gradativa da concentração do isoflurano, e para a manutenção do relaxamento uterino utilizou-se sulfato de

  8. Exploring reasons for the observed inconsistent trial reports on intra-articular injections with hyaluronic acid in the treatment of osteoarthritis

    DEFF Research Database (Denmark)

    Johansen, Mette; Bahrt, Henriette; Altman, Roy D

    2016-01-01

    OBJECTIVE: The aim was to identify factors explaining inconsistent observations concerning the efficacy of intra-articular hyaluronic acid compared to intra-articular sham/control, or non-intervention control, in patients with symptomatic osteoarthritis, based on randomized clinical trials (RCTs......,216 patients), had adequate data available for inclusion in the primary meta-analysis. Overall, compared with placebo, intra-articular hyaluronic acid reduced pain with an effect size of -0.39 [-0.47 to -0.31; P ... with no data available reduced the combined estimate to -0.30 [-0.36 to -0.23; P hyaluronic acid. CONCLUSION: Based on available trial data, intra-articular hyaluronic acid showed a better effect than intra-articular saline on pain reduction in osteoarthritis. Publication bias...

  9. Anti-Inflammatory Effects of Intra-Articular Hyaluronic Acid: A Systematic Review.

    Science.gov (United States)

    Altman, Roy; Bedi, Asheesh; Manjoo, Ajay; Niazi, Faizan; Shaw, Peter; Mease, Philip

    2018-02-01

    Objective Osteoarthritis (OA) is one of the leading causes of disability in the adult population. Common nonoperative treatment options include nonsteroidal anti-inflammatory drugs (NSAIDs), intra-articular corticosteroids, and intra-articular injections of hyaluronic acid (HA). HA is found intrinsically within the knee joint providing viscoelastic properties to the synovial fluid. HA therapy provides anti-inflammatory relief through a number of different pathways, including the suppression of pro-inflammatory cytokines and chemokines. Methods We conducted a systematic review to summarize the published literature on the anti-inflammatory properties of hyaluronic acid in osteoarthritis. Included articles were categorized based on the primary anti-inflammatory responses described within them, by the immediate cell surface receptor protein assessed within the article, or based on the primary theme of the article. Key findings aimed to describe the macromolecules and inflammatory-mediated responses associated with the cell transmembrane receptors. Results Forty-eight articles were included in this systematic review that focused on the general anti-inflammatory effects of HA in knee OA, mediated through receptor-binding relationships with cluster determinant 44 (CD44), toll-like receptor 2 (TLR-2) and 4 (TLR-4), intercellular adhesion molecule-1 (ICAM-1), and layilin (LAYN) cell surface receptors. Higher molecular weight HA (HMWHA) promotes anti-inflammatory responses, whereas short HA oligosaccharides produce inflammatory reactions. Conclusions Intra-articular HA is a viable therapeutic option in treating knee OA and suppressing inflammatory responses. HMWHA is effective in suppressing the key macromolecules that elicit the inflammatory response by short HA oligosaccharides.

  10. Intra-articular corticosteroid injection in diabetic patients with adhesive capsulitis: a randomized controlled trial.

    Science.gov (United States)

    Roh, Young Hak; Yi, Seung Rim; Noh, Jung Ho; Lee, Sung Yup; Oh, Joo Han; Gong, Hyun Sik; Baek, Goo Hyun

    2012-10-01

    An intra-articular corticosteroid injection is considered an effective treatment for idiopathic adhesive capsulitis of the shoulder. This study examined the efficacy of corticosteroid injections for the treatment for adhesive capsulitis in patients with diabetes mellitus. Forty-five diabetic patients were randomized into a corticosteroid injection group or non-injection control group and received the same instruction for a home stretching exercise. The corticosteroid group patients were administered intra-articular corticosteroid injection composed of 40 mg triamcinolone acetonide. Pain by a visual analogue scale, shoulder range of motion, and functional state by the American Shoulder and Elbow score were assessed at the baseline, 4-, 12-, and 24-week follow-up. Diabetic patients treated with corticosteroid injections showed significant improvement in the pain score at 4 weeks and in the functional score at 12 weeks (P = 0.020 and P = 0.042, respectively). The range of motion in forward elevation and internal rotation was significantly higher in the corticosteroid group than in the non-corticosteroid group at the 12-week follow-up (P = 0.030 and 0.045, respectively), but there were no significant differences at the final follow-up between the corticosteroid and non-corticosteroid groups. A corticosteroid injection in diabetic patients decreases the pain perception and accelerates the functional recovery in the early post-injection period. An intra-articular corticosteroid injection is considered a viable option for the treatment for adhesive capsulitis with diabetes. Randomized clinical trial, therapeutic study, Level II.

  11. Intra-articular injection of hyaluronate versus corticosteroid in adhesive capsulitis.

    Science.gov (United States)

    Lim, Tae Kang; Koh, Kyoung Hwan; Shon, Min Soo; Lee, Seung Won; Park, Young Eun; Yoo, Jae Chul

    2014-10-01

    The goal of this study was to prospectively compare the early clinical results of intra-articular injection of hyaluronate or corticosteroid in patients with idiopathic adhesive capsulitis. The authors' hypothesis was that there would be no difference between groups. Sixty-eight patients with idiopathic adhesive capsulitis were equally randomized to receive either corticosteroid or hyaluronate injection. All patients underwent standard physical examination and magnetic resonance imaging. Intra-articular injection was performed through an anterior approach by the same orthopedic surgeon without image guidance. Patients were followed up 2 and 12 weeks after completion of the injection. The primary outcome was the Constant score at week 12. Secondary outcomes included the visual analog scale (VAS) pain score, the American Shoulder and Elbow Surgeons (ASES) score, and range of motion at each time point. No significant differences were noted in preoperative demographic features or baseline shoulder function between groups. After treatment, no significant differences were noted in early clinical outcomes (at weeks 2 and 12) with VAS, ASES, and Constant scores between groups (all P>.05). Evaluation of range of motion showed no difference in forward elevation or external rotation at each time point. Internal rotation was significantly lower at week 2 in the hyaluronate group compared with the corticosteroid group (P=.015). Internal rotation improved at week 12, with no significant difference between groups. Patients treated with intra-articular injection of hyaluronate and corticosteroid for idiopathic adhesive capsulitis showed significant improvement in early clinical scores and range of motion without significant differences between groups. Copyright 2014, SLACK Incorporated.

  12. Outcomes of the distal intraarticular humeral fractures treated by olecranon osteotomy

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    Erhan Yılmaz

    2009-01-01

    Full Text Available Objectives: To evaluate the management and outcome of intraarticular fractures of the distal humerus treated by open reduction and internal fixation using the olecranon osteotomy technique. Materials and methods: Twenty-one patients with in-traarticular fractures of the distal humerus were treated by open reduction and internal fixation. The mean age of the patients was 41.6 years and the mean follow-up pe-riod was 25.3 months. All fractures were type C accord-ing to the AO/ASIF fracture classification system. Chev-ron type olecranon osteotomy was performed within 12-24 h after the injury in all cases but 4 of them. Physical and radiological examination of patients with the appro-priate range checks were made.Results: All fractures united within average duration of 3.2 months. Excellent or good results were found in pa-tients less than 50 years-old, in women, when passing time from injury to surgery was within 12 hours and when early mobilization was achieved. The complica-tions were seen as 2 (9.6% transient neuropraxia of the ulnar nerve, 2 (9.6% failure of fixation, 1 (4.8% het-erotopic ossification and 1 (4.8% olecranon non-union. Fracture type (C1 and time from occurrence of injury to surgery (<12 hours are the main prognostic factors for achieving the excellent/ good functional results.Conclusions: The critical factors for a successful out-come of intraarticular fractures of the distal humerus in-cluded meticulous surgical technique, stable internal fix-ation, surgical experimentation and early controlled postoperative mobilization.

  13. Intra-articular Physeal Fractures of the Distal Femur: A Frequently Missed Diagnosis in Adolescent Athletes.

    Science.gov (United States)

    Pennock, Andrew T; Ellis, Henry B; Willimon, Samuel C; Wyatt, Charles; Broida, Samuel E; Dennis, M Morgan; Bastrom, Tracey

    2017-10-01

    Intra-articular physeal fractures of the distal femur are an uncommon injury pattern, with only a few small case series reported in the literature. To pool patients from 3 high-volume pediatric centers to better understand this injury pattern, to determine outcomes of surgical treatment, and to assess risk factors for complications. Case series; Level of evidence, 4. A multicenter retrospective review of all patients presenting with an intra-articular physeal fracture between 2006 and 2016 was performed. Patient demographic and injury data, surgical data, and postoperative outcomes were documented. Radiographs were evaluated for fracture classification (Salter-Harris), location, and displacement. Differences between patients with and without complications were compared by use of analysis of variance or chi-square tests. A total of 49 patients, with a mean age of 13.5 years (range, 7-17 years), met the inclusion criteria. The majority of fractures were Salter-Harris type III fractures (84%) involving the medial femoral condyle (88%). Football was responsible for 50% of the injuries. The initial diagnosis was missed in 39% of cases, and advanced imaging showed greater mean displacement (6 mm) compared with radiographs (3 mm). All patients underwent surgery and returned to sport with "good to excellent" results after 2 years. Complications were more common in patients with wide-open growth plates, patients with fractures involving the lateral femoral condyle, and patients who were casted ( P < .05). Clinicians evaluating skeletally immature athletes (particularly football players) with acute knee injuries should maintain a high index of suspicion for an intra-articular physeal fracture. These fractures are frequently missed, and advanced imaging may be required to establish the diagnosis. Leg-length discrepancies and angular deformities are not uncommon, and patients should be monitored closely. Surgical outcomes are good when fractures are identified, with high rates

  14. Effectiveness of intra-articular lidocaine injection for reduction of anterior shoulder dislocation: randomized clinical trial

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    Marcel Jun Sugawara Tamaoki

    Full Text Available CONTEXT AND OBJECTIVE: Shoulder dislocation is the most common dislocation among the large joints. The aim here was to compare the effectiveness of reduction of acute anterior shoulder dislocation with or without articular anesthesia. DESIGN AND SETTING: Prospective randomized trial conducted in Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp. METHODS: From March 2008 to December 2009, 42 patients with shoulder dislocation were recruited. Reductions using traction-countertraction for acute anterior shoulder dislocation with and without lidocaine articular anesthesia were compared. As the primary outcome, pain was assessed through application of a visual analogue scale before reduction, and one and five minutes after the reduction maneuver was performed. Complications were also assessed. RESULTS: Forty-two patients were included: 20 in the group without analgesia (control group and 22 in the group that received intra-articular lidocaine injection. The group that received intra-articular lidocaine had a statistically greater decrease in pain over time than shown by the control group, both in the first minute (respectively: mean 2.1 (0 to 5.0, standard deviation, SD 1.3, versus mean 4.9 (2.0 to 7.0, SD 1.5; P < 0.001 and the fifth minute (respectively: mean 1.0; 0 to 3.0; SD = 1.0 versus mean 4.0; 1.0 to 6.0; SD = 1.4; P < 0.001. There was one failure in the control group. There were no other complications in either group. CONCLUSION: Reduction of anterior shoulder dislocation using intra-articular lidocaine injection is effective, since it is safe and diminishes the pain. CLINICAL TRIAL REGISTRATION: ISRCTN27127703.

  15. Intraarticular analgesia after arthroscopic knee surgery: comparison of neostigmine, clonidine, tenoxicam, morphine and bupivacaine.

    Science.gov (United States)

    Alagol, A; Calpur, O U; Usar, P Saral; Turan, N; Pamukcu, Z

    2005-11-01

    We conducted a randomized, placebo-controlled, double blinded study to compare the analgesic effects of intraarticular neostigmine, morphine, tenoxicam, clonidine and bupivacaine in 150 patients undergoing arthroscopic knee surgery. General anaesthesia protocol was same in all patients. At the end of the surgical procedure, patients were randomized into six intraarticular groups equally. Group N received 500 mug neostigmine, Group M received 2 mg morphine, Group T received 20 mg tenoxicam, Group C received 1 microg kg(-1) clonidine, Group B received 100 mg bupivacaine and Group S received saline 20 ml. Visual analog scale scores 0, 30 and 60 min and 2, 4, 6, 12, 24, 48 and 72 h, time to first analgesic need, analgesic consumption at 48 h and 72 h and side effects were noted. Demographic and operational parameters were similar in six groups. All study groups provided analgesia when compared with saline group (P<0.05). Duration of analgesia in Group N and C was longer than other groups (P<0.001). Analgesic consumptions of Group N, C and T were lower than other groups (P<0.01). Pain scores during 2 h postoperatively were lower in all study groups than the control group (P<0.001). In Group B, median pain scores were higher than Groups N and C at 0 min and 30 min postoperatively (P<0.001). Side effects were not significantly different among the six groups. We conclude that the most effective drugs that are administered intraarticularly are neostigmine and clonidine among the five drugs we studied. Tenoxicam provided longer analgesia when compared with morphine and bupivacaine, postoperatively.

  16. Intra-articular pathology associated with isolated posterior cruciate ligament injury on MRI

    International Nuclear Information System (INIS)

    Ringler, Michael D.; Collins, Mark S.; Howe, B.M.; Shotts, Ezekiel E.

    2016-01-01

    Unlike with anterior cruciate ligament injury, little is known about the prevalence of intra-articular pathology associated with isolated posterior cruciate ligament (PCL) injury in the knee. The objectives of this study were to characterize and identify the frequency of meniscal tears and osteochondral injuries in these patients, and to see if management might be affected. Altogether, 48 knee MRI exams with isolated PCL tears were evaluated for the presence of: grade and location of PCL tear, meniscal tear, articular chondral lesion, bone bruise, and fracture. Comparisons between PCL tear grade and location, as well as mechanism of injury when known, with the presence of various intra-articular pathologies, were made using the chi-square or Fisher's exact test as appropriate. In all, 69 % of isolated PCL tears occur in the midsubstance, 27 % proximally. Meniscal tears were seen in 25 % of knees, involving all segments of both menisci, except for the anterior horn medial meniscus. Altogether, 23 % had focal cartilage lesions, usually affecting the central third medial femoral condyle and medial trochlea, while 12.5 % of knees had fractures, and 48 % demonstrated bone bruises, usually involving the central to anterior tibiofemoral joint. The presence of a fracture (p = 0.0123) and proximal location of PCL tear (p = 0.0016) were both associated with the hyperextension mechanism of injury. There were no statistically significant associations between PCL tear grade and presence of intra-articular abnormality. Potentially treatable meniscal tears and osteochondral injuries are relatively prevalent, and demonstrable on MRI in patients with isolated acute PCL injury of the knee. (orig.)

  17. Management of intra-articular fracture of calcaneus by combined percutaneous and minimal internal fixation.

    Science.gov (United States)

    Lamichhane, A; Mahara, D

    2013-01-01

    Fractures of the calcaneus are among the most challenging for the orthopaedic surgeon. The treatment of the intra-articular calcaneum fracture remains controversial due to complications and complexity of surgical anatomy. Treatment of calcaneal fracture ranges from non-operative treatment to operative. We present intraarticular fracture of calcaneus treated by combined percutaneous and minimal internal fixation. All cases evaluated either by X-ray or CT scan. All fractures were sanders two or three type evaluated by CT scan and either joint depression or tongue type fracture by X-ray. Lateral approach was used, posterior facet was exposed, reduced and fixed with one 4 mm canulated cancellous screws and 2 axial pins percutaneously from tuberosity. Clinical evaluation of the outcomes was done by modified Rowe Score. Out of 22 patients, 14 were male and 8 cases were female. Average age of the patients was 30.5 yrs (15-63 yrs). Mode of the injury was RTA in 6 cases and fall from height in 16 cases. There was no soft tissue problem in any patient. All fractures united without secondary displacement in an average of 8 weeks. Average duration of follow up was 26 months (6-37 months). Average Modified Rowe Score was 80 (Range 55-95). Ten patients had excellent, 10 had good and 2 had satisfactory outcome. Intra-articular fracture of the calcaneus can be well managed by minimal opening at the fracture and fixation by single cancellous screw and 2 axial k-wires, so minimizes complications and results in comparable outcomes.

  18. Intra-articular pathology associated with isolated posterior cruciate ligament injury on MRI

    Energy Technology Data Exchange (ETDEWEB)

    Ringler, Michael D.; Collins, Mark S.; Howe, B.M. [Mayo Clinic, Department of Radiology, Rochester, MN (United States); Shotts, Ezekiel E. [NEA Baptist Clinic, Jonesboro, AR (United States)

    2016-12-15

    Unlike with anterior cruciate ligament injury, little is known about the prevalence of intra-articular pathology associated with isolated posterior cruciate ligament (PCL) injury in the knee. The objectives of this study were to characterize and identify the frequency of meniscal tears and osteochondral injuries in these patients, and to see if management might be affected. Altogether, 48 knee MRI exams with isolated PCL tears were evaluated for the presence of: grade and location of PCL tear, meniscal tear, articular chondral lesion, bone bruise, and fracture. Comparisons between PCL tear grade and location, as well as mechanism of injury when known, with the presence of various intra-articular pathologies, were made using the chi-square or Fisher's exact test as appropriate. In all, 69 % of isolated PCL tears occur in the midsubstance, 27 % proximally. Meniscal tears were seen in 25 % of knees, involving all segments of both menisci, except for the anterior horn medial meniscus. Altogether, 23 % had focal cartilage lesions, usually affecting the central third medial femoral condyle and medial trochlea, while 12.5 % of knees had fractures, and 48 % demonstrated bone bruises, usually involving the central to anterior tibiofemoral joint. The presence of a fracture (p = 0.0123) and proximal location of PCL tear (p = 0.0016) were both associated with the hyperextension mechanism of injury. There were no statistically significant associations between PCL tear grade and presence of intra-articular abnormality. Potentially treatable meniscal tears and osteochondral injuries are relatively prevalent, and demonstrable on MRI in patients with isolated acute PCL injury of the knee. (orig.)

  19. Anestesia regional y saturación de oxígeno posoperatorio en el paciente geriátrico

    Directory of Open Access Journals (Sweden)

    Alfonso R León

    2001-06-01

    Full Text Available Numerosos estudios plantean la necesidad de suministrar oxígeno suplementario a pacientes geriátricos en el período posoperatorio (PO, después de anestesia regional como profilaxis de hipoxemia. Teniendo en cuenta lo anterior, se decidió comprobar cómo se comporta la saturación de oxígeno (STO2 en el PO en los pacientes geriátricos que se asistieron con el uso de esta técnica. Previa autorización del consejo científico se seleccionaron al azar 50 pacientes ASA I-II-II (F = 30, K = 20 intervenidos de hemiabdomen inferior y miembros inferiores. Preoperatoriamente se registraron variables demográficas, antecedentes patológicos personales (APP y (STO2. Se realizó anestesia subaracnoidea (SA o peridural (PE. En el PO se realizaron 6 mediciones de la STO2 (cada 10 min durante 1 h a la salida del salón de operaciones. Se procesaron estadísticamente los resultados (comparación de medias. Edad promedio 76 ± 6 años, anestesia PE 20, SA 30, Hb media 10,5 g/L STO2 preoperatorio 94 % ± 1,5. Mediciones en el PO 1ra. 95 % ± 1,8; 2da. 94 % ± 1,3; 3ra. 93 % ± 2,1; 4ta. 95 % ± 1,9; 5ta. 94 % ± 1,5; 6ta. 93 % ± 1,7. No se hallaron diferencias estadísticamente significativas entre estas mediciones, ni en relación con la SOT2 preoperatorias con el uso de esta técnica anestésica en la población geriátricaMany studies state the need to administer supplementary oxygen to elderly patients in the postoperative period (POP after regional anesthesia as a prophylaxis of hipoxemia. Bearing in mind the above mentioned, we decided to confirm the behaviour of oxygen saturation (O2S in the POP of these aged patients that were assisted with this technique. Having cosulted the Scientifc Council, we proceed to a random selection of 50 ASA I-II-III patients (F = 30, K = 20 that underwent an operation of inferior hemiabdomen and lower limbs. Demographic variables, personal pathologic histories (PPH and 02S were obtained before the operation

  20. Assessment of clinical practice guideline methodology for the treatment of knee osteoarthritis with intra-articular hyaluronic acid.

    Science.gov (United States)

    Altman, Roy D; Schemitsch, Emil; Bedi, Asheesh

    2015-10-01

    Clinical practice guidelines are of increasing importance in the decision making for the treatment of knee osteoarthritis. Inconsistent recommendations regarding the use of intra-articular hyaluronic acid for the treatment of knee osteoarthritis have led to confusion among treating physicians. Literature search to identify clinical practice guidelines that provide recommendations regarding the use of intra-articular hyaluronic acid treatment for knee osteoarthritis was conducted. Included guidelines were appraised using the AGREE II instrument. Guideline development methodologies, how the results were assessed, the recommendation formation, and work group composition were summarized. Overall, 10 clinical practice guidelines were identified that met our inclusion criteria. AGREE II domain scores were variable across the included guidelines. The methodology utilized across the guidelines was heterogeneous regarding the evidence inclusion criteria, analysis of evidence results, formulation of clinical practice recommendations, and work group composition. The recommendations provided by the guidelines for intra-articular hyaluronic acid treatment for knee osteoarthritis are highly inconsistent as a result of the variability in guideline methodology. Overall, 30% of the included guidelines recommended against the use of intra-articular hyaluronic acid in the treatment of knee osteoarthritis, while 30% deemed the treatment an appropriate intervention under certain scenarios. The remaining 40% of the guidelines provided either an uncertain recommendation or no recommendation at all, based on the high variability in reviewed evidence regarding efficacy and trial quality. There is a need for a standard "appropriate methodology" that is agreed upon for osteoarthritis clinical practice guidelines in order to prevent the development of conflicting recommendations for intra-articular hyaluronic acid treatment for knee osteoarthritis, and to assure that treating physicians who

  1. Anestesia geral após falha da raquianestesia para procedimento de urgência em paciente com mucopolissacaridose: relato de caso Anestesia general después de la falla de la anestesia raquidea para procedimiento de urgencia en paciente con mucopolisacaridosis: relato de caso General anesthesia after failed spinal block for emergency surgery in a patient with mucopolysaccharidosis: case report

    Directory of Open Access Journals (Sweden)

    Fabiano Timbó Barbosa

    2007-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: As mucopolissacaridoses são grupo heterogêneo de doenças hereditárias que ocorrem devido à deficiência enzimática lisossomal com acúmulo de mucopolissacárides ácidos nos tecidos. A mortalidade perioperatória é de 20% e deve-se principalmente à dificuldade no manuseio das vias aéreas. O objetivo deste relato foi apresentar a conduta anestésica adotada diante de paciente portador de mucopolissacaridose que se apresentou ao centro cirúrgico para realização de intervenção cirúrgica de urgência. RELATO DO CASO: Paciente de 15 anos, sexo masculino, com diagnóstico de mucopolissacaridose, deu entrada no centro cirúrgico para tratamento de hérnia umbilical encarcerada. Após monitorização, foi submetido à anestesia subaracnóidea com bupivacaína hiperbárica na posição sentada. Após identificar falha na raquianestesia, o paciente foi submetido à anestesia geral. A indução anestésica foi realizada com clonidina, fentanil e propofol por via venosa, seguida de intubação sem intercorrências. Após 45 minutos de procedimento cirúrgico, o paciente foi extubado e encaminhado à sala de recuperação pós-anestésica. Lá permaneceu por 12 horas sob observação, recebendo alta para enfermaria sem ter havido intercorrências durante esse período. CONCLUSÕES: No caso em questão, não houve dificuldade no manuseio das vias aéreas. Entretanto, esse é o principal problema encontrado nesse grupo de pacientes, cabendo ao anestesiologista escolher a melhor técnica para garantir adequado manuseio das vias aéreas.JUSTIFICATIVA Y OBJETIVOS: Las mucopolisacaridosis son un grupo heterogéneo de enfermedades hereditarias que ocurren debido a la deficiencia enzimática lisosomal con acumulación de muco polisacáridos ácidos en los tejidos. La mortalidad perioperatoria es de un 20% y se debe principalmente a la dificultad en el manejo de las vías aéreas. El objetivo de este relato fue el de

  2. Hypersensitivity to mechanical and intra-articular electrical stimuli in persons with painful temporomandibular joints

    DEFF Research Database (Denmark)

    Ayesh, Emad; Jensen, Troels Staehelin; Svensson, P

    2007-01-01

    This study tested whether persons with TMJ arthralgia have a modality-specific and site-specific hypersensitivity to somatosensory stimuli assessed by quantitative sensory tests (QST). Forty-three healthy persons and 20 with TMJ arthralgia participated. The QST consisted of: sensory and pain...... detection thresholds and summation threshold to intra-articular electrical stimulation, tactile and pin-prick sensitivity in the TMJ area, pressure-pain threshold and tolerance on the lateral side of the TMJ and on the finger. Persons with TMJ arthralgia had lower pain detection and summation thresholds (P...

  3. Promising Effect Of Intraarticular Ropivacaine In Femoral Neck Fractures Treated With Internal Fixation (Best Poster Award)

    DEFF Research Database (Denmark)

    Bech, Rune Dueholm

    2008-01-01

     Promising Effect Of Intraarticular Ropivacaine In Femoral Neck Fractures Treated With Internal Fixation Rune Bech*, Jens Lauritsen*+,Tine Dimon*, Ole Ovesen*, Claus Emmeluth, Søren Overgaard*. *:Dept. Ortopaedic Surgery, Odense University Hospital, +:Institute of Public Health-dept. biostatistics...... underwent osteosynthesis with 2 canulated hip screws and were prescribed regular paracetamol and supplementary opioid rescue analgesia as necessary. Pilot group: 11 patients received one peroperative (30 mL=100 mg) and 6 postoperative bolus installations  (10 mL=100 mg) of open label Ropivacaine through...

  4. Endoscopically Assisted Resection of a Rare Mass: Intra-Articular Osteochondroma of Shoulder Originated from Scapula

    Directory of Open Access Journals (Sweden)

    Baran Sarikaya

    2016-01-01

    Full Text Available Osteochondromas are the most common benign bone tumors which are mostly seen in the metaphysis of distal femur, proximal tibia, and proximal humerus. As arising from flat bones such as scapula is a rare case, intra-articular osteochondroma is also rare. When the literature is searched it appeared that the scapula and shoulder joint are an uncommon site for osteochondroma. We present a case in which a patient had an osteochondroma placed in shoulder joint and originated from scapula which is a rare situation determined in the literature.

  5. Intra-articular fibroma of tendon sheath in a knee joint associated with iliotibial band friction syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Dong Ho; Choi, Sun Seob; Kim, Soo Jin; Lih, Wang [Dong-A University Medical Center, Busan (Korea, Republic of)

    2015-02-15

    Iliotibial band (ITB) friction syndrome is a common overuse injury typically seen in the active athlete population. A nodular lesion on the inner side of the ITB as an etiology or an accompanying lesion from friction syndrome has been rarely reported. A 45-year-old male presented with recurrent pain and a movable nodule at the lateral joint area, diagnosed as ITB friction syndrome. The nodule was confirmed as a rare intra-articular fibroma of the tendon sheath (FTS) on the basis of histopathologic findings. We describe the MRI findings, arthroscopic and pathologic features, in this case of intra-articular FTS presenting with ITB friction syndrome.

  6. Relato de caso: anestesia em paciente portador de distrofia torácica asfixiante: Síndrome de Jeune

    Directory of Open Access Journals (Sweden)

    Deise Saletti

    2012-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Síndrome de Jeune, ou Distrofia Torácica Asfixiante, é uma doença autossômica recessiva. Esta síndrome é caracterizada por uma displasia óssea com variadas anormalidades: torácica, pancreática, cardíaca, hepática, renal e da retina. A idade em que o quadro clínico dos pacientes se apresenta está correlacionada com a gravidade da doença. Esses pacientes apresentam policondrodistrofia com costelas largas, curtas, horizontais e junções costocondrais irregulares levando a uma caixa torácica rígida e reduzida com grau de injúria respiratória variado. RELATO DO CASO: Paciente do sexo masculino, 4 meses, 7 kg, portador de Distrofia Torácica Asfixiante. Apresentava-se intubado e com caixa torácica reduzida. Ecocardiograma: hipertensão pulmonar leve. Tomografia de tórax: hipoplasia pulmonar. Submetido à toracoplastia bilateral e toracotomia sob anestesia geral. Manutenção da anestesia: infusão contínua de sufentanil e sevoflurano. Parâmetros ventilatórios: ventilação mecânica ciclada à pressão. Com a abertura do tórax, houve melhora dos parâmetros ventilatórios e, após o posicionamento da prótese torácica, observou-se limitação ventilatória. Decidiu-se pela diminuição da prótese torácica com consequente melhora da ventilação. CONCLUSÕES: É imprescindível o diagnóstico de todas as anormalidades presentes para o correto manejo anestésico. Foi necessária observação para adequar ventilação pré- e pós-toracotomia/toracoplastia e para manter o paciente hemodinamicamente estável. A forma mais adequada para ventilação mecânica é a ciclada à pressão para vencer a barreira mecânica. No intraoperatório, é desejável manter o pico de pressão inspiratória o mais baixo possível para minimizar o risco de barotrauma, de impedimento do retorno venoso e diminuição do débito cardíaco.

  7. Anestesia na população negra Anestesia en la población negra Anesthesia in the afro-american population

    Directory of Open Access Journals (Sweden)

    Nilton Bezerra do Vale

    2003-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Percentual significativo dos 12 milhões de negros americanos pode apresentar modificações fisiológicas, fisiopatológicas e farmacológicas capazes de modificar o bom desenvolvimento do ato anestésico; a população brasileira que se considera afro-descendente (40% pode também apresentá-las por causa da mesma origem étnica e geográfica. O objetivo desta revisão é reavaliar o viés da diferença racial em eventuais mudanças no efeito das drogas anestésicas e adjuvantes no ato anestésico. CONTEÚDO: A análise dos estudos fisiopatológicos inerentes à histórica migração do gene africano em relação aos caucasianos mostra significativas diferenças raciais entre o negro americano ou africano, sugerindo uma estreita interface entre a genética e o ambiente, capaz de modificar o procedimento anestésico. As condições sócio-econômicas desfavoráveis da população negra das Américas como resultado de 400 anos de história de escravidão continuam sempre a influenciar na preservação de diferenças culturais e fisiológicas, além da cor da pele: disfunções de sistemas orgânicos estão relacionados com o SNC, SCV, respiratório e renal. No entanto, modificações de efeito de drogas anestésicas e seus adjuvantes, como diminuição do efeito analgésico local do creme anestésico EMLA, aumento do efeito hipnótico do propofol e da toxicidade do paracetamol, menor efeito anti-hipertensivo das drogas que reduzem renina (IECA, bloqueadores beta2 e de AT1, menor ação dos vasodilatadores beta2 e menor fibrinólise do t-PA podem afetar a conduta pré e pós-anestésica, sobretudo em pacientes negros hipertensos, renais, asmáticos ou com acidente vascular cerebral. CONCLUSÕES: Resposta a drogas pode variar entre diferentes populações devido a fatores biológicos (idade, sexo, doença, genéticos, culturais e ambientais. O fator demográfico raça deve ser valorizado na visita ou consulta pr

  8. Anestesia em paciente com Distrofia Muscular de Duchenne: relato de caso Anestesia en paciente con Distrofia Muscular de Duchenne: relato de caso Anesthesia in Duchenne’s Muscular Dystrophy patient: case report

    Directory of Open Access Journals (Sweden)

    Deoclécio Tonelli

    2003-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A distrofia muscular de Duchenne é uma afecção recessiva ligada ao cromossomo X, geralmente diagnosticada na infância, acentuando-se progressivamente até agravar a função respiratória. O objetivo deste relato é apresentar um caso de um paciente com distrofia muscular de Duchenne diagnosticada há 2 anos, submetido à postectomia, sob anestesia geral com cetamina S. RELATO DO CASO: Paciente com 9 anos de idade com Distrofia Muscular de Duchenne diagnosticada há 2 anos, submetido à anestesia geral com levo-cetamina (1,5 mg.kg-1, por via venosa, sob ventilação espontânea assistida manualmente por sistema de Baraka (Mapleson A e bloqueio peniano com bupivacaína a 0,5% (25 mg. Foram usados monitores de pressão arterial não invasiva, oximetria de pulso, cardioscopia e temperatura esofagiana. No decorrer da cirurgia, o caso evoluiu sem intercorrências, sendo que no período pós-operatório o paciente apresentou alguns episódios de vômitos sem outras alterações significativas. Permaneceu internado por 24 horas, tendo alta hospitalar assintomático. CONCLUSÕES: A avaliação pré-anestésica cuidadosa, o uso de monitorização adequada e medicações que não predisponham o aparecimento de complicações tornam seguro o procedimento em pacientes portadores de Distrofia Muscular de Duchenne e seu pós-operatório.JUSTIFICATIVA Y OBJETIVOS: La distrofia muscular de Duchenne es una afección recesiva ligada al cromosoma X, generalmente diagnosticada en la infancia, acentuándose progresivamente hasta agravar la función respiratoria. El objetivo de este relato es presentar un caso de un paciente con distrofia muscular de Duchenne diagnosticada hace 2 años, sometido a la postectomia, sobre anestesia general con cetamina S. RELATO DEL CASO: Paciente con 9 años de edad con Distrofia Muscular de Duchenne diagnosticada hace 2 años, sometido a la anestesia general con levo-cetamina (1,5 mg.kg-1, por v

  9. Anestesia peridural torácica para cirurgia plástica de mama em paciente portadora de miastenia gravis: relato de caso Anestesia peridural torácica para cirugía plástica de mama en paciente portadora de miastenia gravis: relato de caso Thoracic epidural anesthesia for mammaplasty in myasthenia gravis patient: case report

    Directory of Open Access Journals (Sweden)

    Fabiano Timbó Barbosa

    2005-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A miastenia gravis é uma doença crônica, auto-imune, caracterizada pela fraqueza da musculatura esquelética em decorrência da diminuição dos receptores de acetilcolina na junção neuromuscular. O objetivo deste relato é mostrar um caso de paciente com miastenia gravis submetida a anestesia peridural torácica para cirurgia plástica de mama. RELATO DO CASO: Paciente com 51 anos, portadora de miastenia gravis foi submetida a anestesia peridural torácica com bupivacaína e fentanil. Não houve sinais de depressão respiratória. A paciente recebeu alta hospitalar após 36 horas. CONCLUSÕES: O presente caso sugere como conduta anestésica para o paciente portador de miastenia gravis a anestesia peridural como técnica única, sem a obrigatoriedade de intubação orotraqueal.JUSTIFICATIVA Y OBJETIVOS: La miastenia gravis es una enfermedad crónica, auto-inmune, caracterizada por la debilidad de la musculatura esquelética resultante de la disminución de los receptores de acetilcolina en la unión neuromuscular. El objetivo de este relato es mostrar el caso de una paciente con miastenia gravis sometida a anestesia peridural torácica para una cirugía plástica de mama. RELATO DEL CASO: Paciente del sexo femenino, 51 años, portadora de miastenia gravis fue sometida a anestesia peridural torácica con bupivacaína y fentanil. No hubo señales de depresión respiratoria. La paciente recibió alta hospitalaria después de 36 horas. CONCLUSIONES: Este actual caso sugiere como conducta anestésica para el paciente portador de miastenia gravis la anestesia peridural como única técnica, sin la obligatoriedad de intubación orotraqueal.BACKGROUND AND OBJECTIVES: Myasthenia gravis is a chronic autoimmune disease characterized by skeletal muscles weakness promoted by decreased acetylcholine receptors in the neuromuscular junction. This report aimed at describing a case of myasthenia gravis patient submitted to thoracic

  10. Topografia do cone medular da irara (Eira barbara e sua relevância em anestesias epidurais

    Directory of Open Access Journals (Sweden)

    Érika Branco

    2013-06-01

    Full Text Available Encontrada principalmente na América do Sul, a irara é um carnívoro pertencente à família Mustelidae, a qual pouco se tem informações sobre sua morfologia de forma geral. Diante disso, objetivou-se conhecer melhor parte do sistema nervoso desta espécie, mais precisamente a topografia do cone medular, a fim de subsidiar intervenções anestésicas peridurais nesta, uma vez que a clínica de animais selvagens vem crescendo a cada dia. Foram estudados três exemplares machos, adultos, provenientes da área de Mina Bauxita, Paragominas, doados ao Laboratório de Pesquisa Morfológica Animal (LaPMA, Universidade Federal Rural da Amazônia (UFRA, Belém, os quais foram radiografados e dissecados ao nível lombossacral, seguido de exposição do cone medular. Este, por sua vez, situou-se entre L4-L6 possuindo comprimento médio de 4,31cm, o que nos levou a sugerir a região sacrococcígea como ponde ideal para prática de anestesias epidurais nesta espécie.

  11. Anestesia para cesariana em paciente com síndrome de Guillain-Barré: relato de caso

    Directory of Open Access Journals (Sweden)

    Daniel Volquind

    2013-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A Síndrome de Guillain-Barré durante a gestação é considerada uma CIRURGIA, Cesárea; complicação neurológica rara e o manejo anestésico para a cesariana nessas pacientes ainda não é consenso na literatura. O objetivo deste artigo é relatar o caso de uma paciente gestante portadora da Síndrome de Guillain-Barré submetida à cesariana. RELATO DO CASO: Paciente feminina, 22 anos, com 35 semanas e cinco dias de idade gestacional, da celularidade. A técnica anestésica empregada foi a anestesia geral, induzida com propofol 1,5 mg.kg-1 e mantida com sevofiurano 2% em oxigênio e fentanil 3 µg.kg-1. O procedimento transcorreu sem complicações, tanto para a gestante quanto para o concepto. A paciente obteve alta no décimo dia de internação, após melhora progressiva do quadro neurológico. CONCLUSÕES: A técnica anestésica a ser empregada em gestantes portadoras da Síndrome de Guillain-Barré que necessitam fazer cesariana permanece como escolha do anestesiologista, que deve ser guiado pelo quadro clínico e pelas comorbidades de cada paciente.

  12. Intraarticular Injections of Platelet-rich Plasma (PRPin the Management of Knee Osteoarthritis

    Directory of Open Access Journals (Sweden)

    E. Carlos Rodriguez-Merchan

    2013-09-01

    Full Text Available   The clinical use of PRP therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. Another reason is the strong advertisement of PRP procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific evidence. Hence, PubMed articles related to the clinical use of PRP in knee osteoarthritis were searched using the key words: PRP, knee and osteoarthritis in order to study these claims. A total of 20 reports were found directly related to the topic. The aforementioned clinical studies suggest that intraarticular injections of PRP could have preventive effects against osteoarthritis progression. However, presently there is no clear evidence from well-designed clinical trials that intraarticular injections of PRP are efficacious in osteoarthritis. Therefore, at this time the efficacy of PRP requires more investigation, wherein better scientific studies should be performed that include high powered randomized controlled trials.

  13. Comparative study of intra-articular lidocaine and intravenous meperidine/diazepam for shoulder dislocations.

    Science.gov (United States)

    Orlinsky, Michael; Shon, Sammy; Chiang, Charles; Chan, Linda; Carter, Paul

    2002-04-01

    The purpose of this study was to compare the analgesic effectiveness of intra-articular lidocaine versus intravenous meperidine and diazepam during the reduction of anterior shoulder dislocations. Patients were randomized to one of the two methods before the reduction of shoulder dislocations. Patients marked a visual analog pain scale at baseline, after anesthesia just before reduction, and at the time of discharge. Interference with the procedure caused by pain or lack of muscle relaxation, perception of adequacy of analgesia by the patient, adverse effects, and time to discharge from the Emergency Department (ED) were measured. Differences of outcomes, relative risks (RR), and 95% confidence intervals (CIs) were derived. Fifty-four patients with anterior shoulder dislocations presenting from May 21, 1998 through January 21, 1999 were included in this study; 29 were randomly assigned to receive intra-articular lidocaine (IAL) and 25 to receive intravenous meperidine/diazepam (IVMD). IAL was less effective than IVMD in relieving pre-reduction pain (p = 0.045) but equally effective in overall pain relief (p = 0.98). IAL was more effective than IVMD in shortening recovery time (p = 0.025). There was an indication favoring IVMD in terms of physician-perceived muscle relaxation and patient's perception of analgesia adequacy. In conclusion, although the IVMD method appears to have some clinically and statistically significant advantages, IAL possesses some favorable features that render it to be an analgesia alternative in shoulder dislocation reduction.

  14. Intra-articular injection of tenoxicam following temporomandibular joint arthrocentesis: a pilot study.

    Science.gov (United States)

    Aktas, I; Yalcin, S; Sencer, S

    2010-05-01

    This study examined the clinical and radiological effects of intra-articular tenoxicam injection following arthrocentesis and compared them with arthrocentesis alone in patients with disc displacement without reduction (DDwoR). 24 temporomandibular joints (TMJs) in 21 patients with DDwoR were studied. Patients were divided randomly into Group A in which only arthrocentesis was performed (14 TMJs in 14 patients) and Group AT which received arthrocentesis plus intra-articular injection of tenoxicam (10 TMJs in 7 patients). Patients were evaluated before the procedure, on postoperative day 7, then 2, 3, 4 weeks, and 2, 3, 4, 5, 6 months postoperatively. Intensity of joint pain was assessed using a visual analog scale. Maximum mouth opening was recorded at each follow-up. TMJ sounds and palpation scores were noted as positive or negative. Magnetic resonance imaging (MRI) was performed before and 6 months after treatment in both groups. Disc form, disc location during neutral position, reduction with movement, joint effusion, structures of the articular surfaces, and bone marrow anomalies were evaluated all in MRIs. Both treatments succesfully increased maximum mouth opening and reduced TMJ pain; there were no complications. Difference between the groups was not statistically significant and a larger controlled study is necessary to clarify this use of tenoxicam. Copyright 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  15. Prognostic factors after intra-articular hyaluronic acid injection in ankle osteoarthritis.

    Science.gov (United States)

    Han, Seung Hwan; Park, Do Young; Kim, Tae Hun

    2014-07-01

    The goal of this study was to identify baseline prognostic factors of outcome in ankle osteoarthritis patients after intra-articular hyaluronic acid injection. Patients with ankle osteoarthritis who received hyaluronic acid injection therapy were retrospectively reviewed. Each patient received weekly intra-articular hyaluronic acid injections (2 mL) for 3 weeks. Six predictors including gender, age, symptom duration, radiographic osteoarthritis stage, radiographic subchondral cyst, and fracture history were evaluated. Visual analogue scale (VAS) and patient satisfaction were evaluated as outcome measures. These predictors and outcome measurements were included in a logistic regression model for statistical analysis. Total of 40 consecutive patients (21 male, 19 female) were included in this study. Mean age was 60.6. Average follow up period was 13 months. The mean VAS recorded 3, 6, and 12 months after the first injection was 3.6 (SD 2.54, phyaluronic acid injection for ankle osteoarthritis is a safe and effective treatment, careful selection of patients should be made according to the above prognostic predictors.

  16. Efficacy of Intra-Articular Injection of Hyaluronic Acid in the Treatment of Knee Osteoarthritis

    Directory of Open Access Journals (Sweden)

    SS Narayanan

    2009-05-01

    Full Text Available This study was conducted to evaluate the efficacy of intra- articular injection of hyaluronic acid for the treatment of knee osteoarthritis. Patients with knee osteoarthritis were followed for a period of six months to assess the efficacy of intra-articular injection of hyaluronic acid given three times in three consecutive weeks. Fifty patients were reviewed at two, eight and 24 weeks post-injection. The average age was 60.9 years and female to male ratio was 3:1. Patients were assessed using the Lequesne Algofunctional Index for function, and the visual analogue score for pain and side effects. We found that the knee pain reduced and the function improved in most patients and these beneficial effects maintain till the last follow up. The only side effect noted was one case of acute non-septic joint effusion after the 3rd injection. We concluded that intra-articular injection of hyaluronic acid can produce pain relief and functional improvement for up to 6 months.

  17. Percutaneous Reduction and Screw Fixation of Displaced Intra-articular Fractures of the Calcaneus.

    Science.gov (United States)

    Tantavisut, Saran; Phisitkul, Phinit; Westerlind, Brian O; Gao, Yubo; Karam, Matthew D; Marsh, John L

    2017-04-01

    Extensile open approaches to reduce and fix intra-articular calcaneal fractures are associated with high levels of wound complications. To avoid these complications, a technique of percutaneous reduction and fixation with screws alone was developed. This study assessed the clinical outcomes, radiographs, and postoperative CT scans after operative treatment with this technique. 153 consecutive patients with 182 intra-articular calcaneal fractures were reviewed. All patients were assessed for early postoperative complications at 3 months from the injury. The clinical results were assessed for patients seen at a minimum of 1 year after surgery (mean follow-up of 2.6 years; 90 patients, 106 feet). In patients who had both preoperative and postoperative CT scans (50 patients, 60 feet), the articular reduction was quantitatively analyzed. At the 3-month follow-up, there were 1% superficial infections and 1% rate of screw irritation. The complications at a minimum of 1 year after injury included screw irritation 9.3%, subtalar osteoarthritis requiring subtalar fusion 5.5%, malunion 1.8%, and deep infection 0.9%. Bohler angle, calcaneal facet height, and width were significantly improved postoperatively ( P fractures using screws alone based on articular reduction and level of residual pain. Level IV, retrospective case series.

  18. Intraarticular calcaneal fractures. Clinical results and functional analysis of the surgical treatment

    International Nuclear Information System (INIS)

    Calixto B, Luis Fernando; Gomez R, Jairo Fernando; Prieto S, Hernan Augusto

    2004-01-01

    This study evaluated the clinical and functional outcome of open reduction and internal fixation in intraarticular calcaneal fractures 22 patients with 24 intra-articular fractures of calcaneous were treated, 19 with open reduction and internal fixation using a 3.5 mm AO/ASIF calcaneal plate. The fractures were classified according the Sanders tomographic system. The Bohler angle was measured before and after the surgery. All patients were evaluated using the functional ankle-hind foot AOFAS scale (American Orthopaedics Foot and Ankle Society) 6 and 12 months after the surgery. Mean age was 39.8 years. The distribution according the type of fracture was: Sanders II: 41.67% and Sanders III: 58.33%. The mean value of the initial Bohler angle was 11.45% and the final was 24.5 degrees. The functional outcome after 6 months was 70 points and after 12 months was 82 points. There were only two complications (12.5%) a fistula and a wound dehiscence. The displaced and slightly comminuted intra articular fractures have the calcaneus (Sandres II and Sandres III) benefit of ORIF obtaining good functional outcomes 6 and 12 months after surgery. This procedure allows a better articular surface reduction, a satisfactory Bohler angle correction and earlier rehabilitation

  19. Localized tenosynovial giant cell tumor in both knee joints

    International Nuclear Information System (INIS)

    Kim, Hyun Su; Kwon, Jong Won; Ahn, Jin Hwan; Chang, Moon Jong; Cho, Eun Yoon

    2010-01-01

    Tenosynovial giant cell tumor, previously called pigmented villonodular synovitis (PVNS), is a rare benign neoplastic process that may involve the synovium of the joint. The disorder is usually monoarticular and only a few cases have been reported on polyarticular involvement. Herein, we present a case of localized intra-articular tenosynovial giant cell tumor in a 29-year-old man involving both knee joints with a description of the MR imaging and histological findings. (orig.)

  20. Intra-Articular Analgesia and Steroid Reduce Pain Sensitivity in Knee OA Patients: An Interventional Cohort Study

    Directory of Open Access Journals (Sweden)

    Tanja Schjødt Jørgensen

    2014-01-01

    Full Text Available Objectives. To assess the effects of intra-articular therapy on pain sensitivity in the knee and surrounding tissues in knee OA patients. Methods. Twenty-five knee OA patients with symptomatic knee OA were included in this interventional cohort study. Pressure pain thresholds (PPT were recorded before, immediately after, and two weeks after ultrasound guided intra-articular injection of lidocaine combined with glucocorticosteroid. Computer-controlled and manual pressure algometers were used to assess PPT on the knee, vastus lateralis, tibialis anterior, and the extensor carpi radialis longus muscles (control site. Results. Significantly increased PPTs were found following intra-articular injection, at both the knee P<0.0001 and the surrounding muscles P<0.042. The treatment effects were sustained for two weeks, and at some points the effect was even greater at two weeks P<0.026. Albeit not statistically significant, a similar trend was observed at the control site. Conclusions. Intra-articular anesthesia, combined with glucocorticosteroid, reduced pain sensitivity in both the knee and surrounding muscles for at least two weeks.

  1. A protocol for developing a clinical practice guideline for intra-articular injection for treating knee osteoarthritis

    Directory of Open Access Journals (Sweden)

    Dan Xing

    2018-01-01

    Ethics and dissemination: The protocol will provide us a roadmap to systematically develop evidence-based CPG for intra-articular injection for knee OA. The work will be disseminated electronically and in print. The guideline would be the first CPG that is developed primarily by orthopedic specialists in China and strictly based on systematic methodology.

  2. Body mass index and active range of motion exercise treatment after intra-articular injection in adhesive capsulitis

    Directory of Open Access Journals (Sweden)

    Hsi-Hsien Lin

    2013-04-01

    Conclusion: Active range of motion exercise after an intra-articular injection of corticosteroid and lidocaine improved pain and functional outcome at 8 weeks in normal-weight (BMI < 25 kg/m2 patients with primary adhesive capsulitis. Manipulation under anesthesia may be considered a priority in overweight patients.

  3. Operative Treatment of Intra-Articular Distal Radius Fractures With versus Without Arthroscopy : Study protocol for a randomised controlled trial

    NARCIS (Netherlands)

    M.A.M. Mulders (Marjolein A. M.); C.A. Selles (Caroline); J.W. Colaris (Joost); R.W. Peters (Rolf); M. van Heijl (Mark); B.I. Cleffken (Berry); N.W.L. Schep (Niels)

    2018-01-01

    markdownabstract__Background:__ In the past several years, an increase in open reduction and internal fixation (ORIF) for intra-articular distal radius fractures has been observed. This technique leads to a quicker recovery of function compared to non-operative treatment. However, some patients

  4. Operative Treatment of Intra-Articular Distal Radius Fractures With versus Without Arthroscopy: study protocol for a randomised controlled trial

    NARCIS (Netherlands)

    Mulders, Marjolein A. M.; Selles, Caroline A.; Colaris, Joost W.; Peters, Rolf W.; van Heijl, Mark; Cleffken, Berry I.; Schep, Niels W. L.

    2018-01-01

    Background: In the past several years, an increase in open reduction and internal fixation (ORIF) for intra-articular distal radius fractures has been observed. This technique leads to a quicker recovery of function compared to non-operative treatment. However, some patients continue to have a

  5. Are intra-articular injections of hyaluronic acid effective for the treatment of temporomandibular disorders? A systematic review.

    Science.gov (United States)

    Goiato, M C; da Silva, E V F; de Medeiros, R A; Túrcio, K H L; Dos Santos, D M

    2016-12-01

    This systematic review aimed to investigate whether intra-articular injections of hyaluronic acid (HA) are better than other drugs used in temporomandibular joint arthrocentesis, for the improvement of temporomandibular disorder (TMD) symptoms. Two independent reviewers performed an electronic search of the MEDLINE and Web of Science databases for relevant studies published in English up to March 2016. The key words used included a combination of 'hyaluronic acid', 'viscosupplementation', 'intra-articular injections', 'corticosteroids', or 'non steroidal anti inflammatory agents' with 'temporomandibular disorder'. Selected studies were randomized clinical trials and prospective or retrospective studies that primarily investigated the application of HA injections compared to other intra-articular medications for the treatment of TMD. The initial screening yielded 523 articles. After evaluation of the titles and abstracts, eight were selected. Full texts of these articles were accessed and all fulfilled the inclusion criteria. Intra-articular injections of HA are beneficial in improving the pain and/or functional symptoms of TMDs. However, other drug therapies, such as corticosteroid and non-steroidal anti-inflammatory drug injections, can be used with satisfactory results. Well-designed clinical studies are necessary to identify an adequate protocol, the number of sessions needed, and the appropriate molecular weight of HA for use. Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  6. Uso de la anestesia en la gasometría arterial

    OpenAIRE

    Gilabert Leiva, Gema

    2017-01-01

    Introducción. La gasometría arterial es una técnica invasiva que permite valorar el intercambio de gases. Se considera el procedimiento de laboratorio más doloroso experimentado por los pacientes. El dolor experimentado durante la punción produce hiperventilación, disminución del dióxido de carbono y aumento del oxígeno en la sangre. Por ello se recomienda el uso de anestésico local subcutáneo sin vasoconstrictor. Objetivo. Conocer el uso del anestésico local en la gasometría arterial por par...

  7. Anestesia em paciente portadora de doença de moyamoya: relato de caso Anestesia en paciente portadora de enfermedad de moyamoya: relato de caso Anesthesia in patient with moyamoya disease: case report

    Directory of Open Access Journals (Sweden)

    Adriano Bechara de Souza Hobaika

    2005-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A doença de moyamoya é uma vasculopatia cerebral progressiva rara, mais freqüentemente diagnosticada em populações asiáticas, mas que também vem sendo identificada no Brasil. Durante a sua vida, pacientes portadores desta doença podem ser submetidos aos mais variados tipos de procedimentos cirúrgicos. O anestesiologista deve entender a fisiopatologia da doença e instituir as medidas peri-operatórias mais adequadas, no intuito de melhorar o prognóstico destes pacientes. RELATO DO CASO: Paciente do sexo feminino, 22 anos, com insuficiência renal crônica, portadora da doença de moyamoya, submetida à intervenção cirúrgica para instalação de fístula arteriovenosa. A anestesia foi induzida com fentanil, propofol e atracúrio e mantida com sevoflurano. Durante o procedimento, a paciente foi mantida em normocapnia e normotermia. A extubação foi realizada e a paciente transferida à sala de recuperação pós-anestésica sem complicações. CONCLUSÕES: Este artigo apresenta os cuidados anestésicos dispensados a uma paciente portadora da doença de moyamoya.JUSTIFICATIVA Y OBJETIVOS: La enfermedad de moyamoya es una vasculopatia cerebral progresiva rara, más frecuentemente diagnosticada en individuos asiáticos, y que también viene siendo identificada en Brasil. Durante su vida, pacientes portadores de esta enfermedad pueden ser sometidos a los más variados tipos de procedimientos quirúrgicos. El anestesiologista debe entender la fisiopatología de la enfermedad e instituir las medidas peri-operatorias más adecuadas, en el designio de mejorar el pronóstico de estos enfermos. RELATO DEL CASO: Paciente del sexo femenino, 22 años, insuficiencia renal crónica, portadora de la enfermedad de moyamoya, sometida a intervención quirúrgica para la instalación de fístula arteriovenosa. La anestesia fue inducida con fentanil, propofol y atracúrio y mantenida con sevoflurano. Durante el procedimiento

  8. Influência da técnica de anestesia no tempo de ocupação de sala cirúrgica nas operações anorretais Influence of the anesthetic technique on the time spent in operating rooms in anorectal procedures

    Directory of Open Access Journals (Sweden)

    Paulo Gustavo Kotze

    2008-06-01

    Full Text Available INTRODUÇÃO: atualmente cerca de 90% das operações anorretais são realizadas em regime ambulatorial. A técnica anestésica é fator fundamental na busca de reduzido tempo de internação, agilidade no ambiente cirúrgico e redução de custos nestes procedimentos. Não há consenso na literatura sobre qual o melhor tipo de anestesia para essas operações. OBJETIVO: comparar o tempo de ocupação de sala cirúrgica em pacientes submetidos a operações anorretais através da técnica de raquianestesia com bupivacaína 0,5% isobárica comparada com a técnica de anestesia venosa com propofol associada ao bloqueio perianal local com lidocaína a 2% e bupivacaína 0,5%. MÉTODOS: Foram incluídos 99 pacientes divididos em 2 grupos: grupo I (raquianestesia, composto por 50 pacientes e grupo II (anestesia combinada, composto por 49 pacientes. Foram estudados os procedimentos cirúrgicos e o tempo de procedimento anestésico-cirúrgico, e medida indireta da ocupação da sala cirúrgica. RESULTADOS: Não houve diferença estatística significativa entre os grupos estudados em relação ao tipo de procedimento cirúrgico, sexo e idade. O tempo médio do procedimento anestésico-cirúrgico, no grupo I foi de 53,1 min e de 44,08 min no grupo II (p=0,034. CONCLUSÕES: As duas técnicas estudadas foram eficazes. Houve menor tempo de procedimento anestésico-cirúrgico nos pacientes operados com anestesia combinada, com significância estatística.INTRODUCTION: around ninety percent of anorectal surgical procedures are performed as day cases. The choice of a proper anesthetic technique is important to achieve reduced time in the operating rooms, hospital stay and low costs. There is no evidence in the literature that a superior type of anesthesia for these procedures exists. OBJECTIVE: to compare the time spent on operating rooms in patients submitted to anorectal surgical procedures through spinal anesthesia (0,5% bupivacaine with combined anesthesia

  9. Effect of Hypertonic Saline in Intra-Articular Hydraulic Distension for Adhesive Capsulitis.

    Science.gov (United States)

    Lee, Jong Hwa; Kim, Sang Beom; Lee, Kyeong Woo; Lee, Sook Joung; Lee, Jae Uk

    2015-07-01

    Maintaining the integrity of the capsule along with infusing a sufficient amount of fluid is 1 of the therapeutic concepts in intra-articular hydraulic distension (IHD) for adhesive capsulitis. It has been known that hypertonic saline solution decreases tissue edema and increases the fluid volume within the epidural space, causing microdissection, in epidural adhesiolysis. To investigate the effect of hypertonic saline solution in capsule-preserving intra-articular hydraulic distension (CPIHD) for adhesive capsulitis. Prospective randomized controlled trial. University outpatient clinic of physical medicine and rehabilitation. A total of 64 patients who were diagnosed as adhesive capsulitis of shoulder were randomly assigned to 1 of 2 treatment groups. The hypertonic saline group was treated by CPIHD with hypertonic saline (3% NaCl), and the normal saline group with normal saline solution (0.9% NaCl). Both groups were treated with CPIHD, a method that preserves the capsule with maximal distension without inducing capsule rupture. The volume of saline solution necessary to adequately distend the capsule was recorded. Injection materials contained 4 mL of 1% lidocaine, 1 mL of triamcinolone (10 mg), and saline solution (hypertonic or normal saline). The intra-articular injection was monitored with ultrasound to maximize the infused volume while preserving the capsule. The Shoulder Pain and Disability Index (SPADI) and shoulder passive range of motion (PROM) was measured before the procedure and 2 weeks after CPIHD. The mean CPIHD volume was 20.2 ± 5.2 mL for the hypertonic saline group and 19.5 ± 5.9 mL for the normal saline group. The hypertonic saline group showed statistically significant improvement in shoulder PROM and SPADI score compared with the normal saline group. Side effects such as soreness or complications related to injection were not reported. Our results suggest that CPIHD with hypertonic saline solution is more effective than that using normal

  10. FUNCTIONAL OUTCOME OF INTERNAL FIXATION FOR DISPLACED INTRA-ARTICULAR CALCANEAL FRACTURE

    Directory of Open Access Journals (Sweden)

    Saket Jati

    2016-12-01

    Full Text Available BACKGROUND There are always difference of opinion in the importance of Bohler’s angle in evaluating the severity of displaced intra-articular calcaneal fractures and predicting the functional outcome following surgical fixation. The purpose of this research, the relationship exists between Bohler’s angle and the injury severity of displaced calcaneal fractures and between surgical improvement of Bohler’s angle and its practical outcome. MATERIALS AND METHODS Patients were treated surgically for unilateral closed displaced intra-articular calcaneal fractures from May 2014 to October 2016 were identified. The Bohler’s angles of bilateral calcaneus were measured and was compared to the dimension of the uninjured foot was used as its normal control. The difference in the value of Bohler’s angle measured preoperatively or after surgery between the angle of the damaged foot and that of the contralateral calcaneus was calculated, respectively. The change in Bohler’s angle by ratio was calculated by dividing the variation in the value of Bohler’s angle between bilateral calcaneus by its typical control. The injury severity was assessed according to Sanders classification. The functional outcomes were assessed using American Orthopaedic Foot and Ankle Society hindfoot scores. RESULTS 30 patients were included into the study with a mean follow-up duration of 30 months. According to Sanders classification, the fracture pattern included 12 type II, 10 type III and 8 type IV fractures. According to American Orthopaedic Foot and Ankle Society hindfoot scoring system, the excellent, good, fair and poor results were achieved in 10, 8, 4 and 2 patients, respectively. The preoperative Bohler’s angle, difference value of Bohler’s angle between bilateral calcaneus and change in Bohler’s angle by ratio each has a significant relationship with Sanders classification (P=0.003; P=0.004; P=0.005, respectively, however, is not correlated with

  11. Amputação interescapulotorácica sob anestesia locorregional

    Directory of Open Access Journals (Sweden)

    José Alves de Moraes

    Full Text Available Forequarter amputations are an uncommon option for the treatment of upper limb and shoulder girdle tumors nowadays. This procedure can be done by different approaches and general anesthesia is commonly used. The authors report a case of forequarter amputation by the posterior approach performed for treatment of a soft-tissue sarcoma under a brachial plexus block associated with venous sedation and local anesthesia.

  12. Paresia transitória unilateral combinada do nervo hipoglosso e do nervo lingual após intubação para anestesia

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    Hulya Ulusoy

    2014-04-01

    Full Text Available Lesões de nervos podem ocorrer na região faringolaríngea durante a anestesia geral. Os nervos mais comumente lesionados são o hipoglosso, lingual e laríngeo recorrente. As lesões podem surgir em decorrência de vários fatores, como, por exemplo, durante a laringoscopia, intubação endotraqueal e inserção de tubo e por pressão do balão, ventilação com máscara, manobra aérea tripla, via aérea orofaríngea, modo de inserção do tubo, posição da cabeça e do pescoço e aspiração. As lesões nervosas nessa região podem acometer um único nervo isolado ou causar a paralisia de dois nervos em conjunto, como a do nervo laríngeo recorrente e hipoglosso (síndrome de Tapia. No entanto, a lesão combinada dos nervos lingual e hipoglosso após intubação para anestesia é uma condição muito mais rara. O risco dessa lesão pode ser reduzido por meio de medidas preventivas. Descrevemos um caso de paresia unilateral combinada dos nervos hipoglosso e lingual após intubação para anestesia.

  13. Ablação curativa da fibrilação atrial: comparação entre sedação profunda e anestesia geral

    Directory of Open Access Journals (Sweden)

    Elizabeth Bessadas Penna Firme

    Full Text Available OBJETIVO: Comparar sedação profunda com anestesia geral para ablação curativa de fibrilação atrial. MÉTODOS: Estudo prospectivo, aleatório, com 32 pacientes, idades entre 18 e 65 anos, ASA 2 e 3, IMC d" 30kg/m², distribuídos em dois grupos: sedação profunda (G1 e anestesia geral (G2. Todos receberam midazolan (0,5mg/kg venoso. O G1 recebeu propofol (1mg/kg e máscara facial de O2, seguido da infusão contínua de propofol (25-50mg/kg/min e remifentanil (0,01-0,05µg/kg/min. O G2 recebeu propofol (2mg/kg e máscara laríngea com tubo de drenagem, seguido da infusão contínua de propofol (60-100mg/kg/min e remifentanil (0,06-0,1µg/kg/min. Foram comparados: frequência cardíaca, pressão arterial invasiva, complicações, recidiva (desfecho em três meses e gasometrias. RESULTADOS: Os pacientes do G1 apresentaram gasometrias arteriais com níveis de PaCO2 maiores e pH menores (p=0,001 e maior incidência de tosse. Ocorreu diminuição da PAM e FC no G2. Exceto a tosse, as complicações e recidivas foram semelhantes em ambos os grupos. CONCLUSÃO: Ambas as técnicas podem ser utilizadas para a ablação curativa da fibrilação atrial. A anestesia geral proporcionou menores alterações respiratórias e maior imobilidade do paciente.

  14. In vivo human adipose-derived mesenchymal stem cell tracking after intra-articular delivery in a rat osteoarthritis model

    Directory of Open Access Journals (Sweden)

    Meng Li

    2016-11-01

    Full Text Available Abstract Background Human adipose-derived mesenchymal stem cells (haMSCs have shown efficacy in treating osteoarthritis (OA both preclinically and clinically via intra-articular (IA injection. However, understanding the mode of action of the cell therapy has been limited by cell tracking capability and correlation between the pharmacokinetics of the injected cells and the intended pharmacodynamics effect. This study aims to explore methodology and to understand in vivo biodistribution of clinical-grade haMSCs labeled with fluorescent dye and injected into an immunocompetent OA rat model. Methods haMSCs labeled with fluorescent dye were investigated for their proliferation and differentiation capabilities. Labeled cells were used to establish detection threshold of a noninvasive biofluorescent imaging system before the cells (2.5 × 106 were injected into a conventional rat OA model induced by medial meniscectomy for 8 weeks. We attempted to reveal the existence of labeled cells in vivo by imaging and a molecular biomarker approach, and to correlate with the in vivo efficacy and physical presence over a follow-up period up to 10 weeks. Results In vitro proliferation and differentiation of haMSCs were not affected by the labeling of DiD dye. Detection thresholds of the labeled cells in vitro and in vivo were determined to be 104 and 105 cells, respectively. When 2.5 × 106 haMSCs were injected into the joints of a rat OA model, fluorescent signals (or >105 cells lasted for about 10 weeks in the surgical knee joint at the same time as efficacy was observed. Signals in nonsurgical rats only lasted for 4 weeks. The human MSCs were shown to engraft to the rat joint tissues and were proliferative. Human FOXP2 gene was only detected in the knee joint tissue, suggesting limited biodistribution locally to the joints. Conclusions The current study represents the first attempt to correlate cell therapy efficacy on OA with the physical presence

  15. In vivo human adipose-derived mesenchymal stem cell tracking after intra-articular delivery in a rat osteoarthritis model.

    Science.gov (United States)

    Li, Meng; Luo, Xuan; Lv, Xiaoteng; Liu, Victor; Zhao, Guangyu; Zhang, Xue; Cao, Wei; Wang, Richard; Wang, Wen

    2016-11-10

    Human adipose-derived mesenchymal stem cells (haMSCs) have shown efficacy in treating osteoarthritis (OA) both preclinically and clinically via intra-articular (IA) injection. However, understanding the mode of action of the cell therapy has been limited by cell tracking capability and correlation between the pharmacokinetics of the injected cells and the intended pharmacodynamics effect. This study aims to explore methodology and to understand in vivo biodistribution of clinical-grade haMSCs labeled with fluorescent dye and injected into an immunocompetent OA rat model. haMSCs labeled with fluorescent dye were investigated for their proliferation and differentiation capabilities. Labeled cells were used to establish detection threshold of a noninvasive biofluorescent imaging system before the cells (2.5 × 10 6 ) were injected into a conventional rat OA model induced by medial meniscectomy for 8 weeks. We attempted to reveal the existence of labeled cells in vivo by imaging and a molecular biomarker approach, and to correlate with the in vivo efficacy and physical presence over a follow-up period up to 10 weeks. In vitro proliferation and differentiation of haMSCs were not affected by the labeling of DiD dye. Detection thresholds of the labeled cells in vitro and in vivo were determined to be 10 4 and 10 5 cells, respectively. When 2.5 × 10 6 haMSCs were injected into the joints of a rat OA model, fluorescent signals (or >10 5 cells) lasted for about 10 weeks in the surgical knee joint at the same time as efficacy was observed. Signals in nonsurgical rats only lasted for 4 weeks. The human MSCs were shown to engraft to the rat joint tissues and were proliferative. Human FOXP2 gene was only detected in the knee joint tissue, suggesting limited biodistribution locally to the joints. The current study represents the first attempt to correlate cell therapy efficacy on OA with the physical presence of the injected haMSCs in the OA model, and demonstrates

  16. Hipotensión arterial y variabilidad de la frecuencia cardiaca en pacientes embarazadas llevadas a cesarea bajo anestesia raquídea

    OpenAIRE

    Amaya Rios, Juan Carlos; Garcia Montaño, Nestor Ivan

    2015-01-01

    INTRODUCCION La hipotensión arterial por anestesia raquídea en embarazadas llevadas a cesárea es frecuente y deletérea para la madre y el feto, sin que a la fecha exista una herramienta clínicamente útil para predecirla. La variabilidad de la frecuencia cardiaca es una medida que estima la actividad del sistema nervioso autónomo y algunos estudio iniciales indican una posible utilidad como herramienta predictiva de hipotensión arterial en esta población. METODOLOGIA Se realizó un es...

  17. Comparación de costo-efectividad entre dos técnicas anestésicas: anestesia con sevofluoraneremifentanil frente a isofluorane-remifentanil

    OpenAIRE

    Carvajal C., Marco A.; Rincón F, Ismael; Montes R, Félix

    2010-01-01

    Nos encontramos en la era de la optimización de costos, por lo que es necesario realizar estudios farmacoeconómicos para identificar la costo- efectividad de los anestésicos actuales. Metodología: este estudio prospectivo, cegado al paciente, comparó los costos directos, los tiempos de recuperación y satisfacción de 45 pacientes que se asignaron aleatoriamente a dos grupos de anestesia balanceada (grupo sevofluoraneremifentanil n = 24 o grupo isofluoraneremifentanil n = 21) que iban a ser som...

  18. Efeito de diferentes formas de suplementação dietética e da anestesia peribulbar sobre a função da retina

    OpenAIRE

    Bannach, Tatiana Charello

    2012-01-01

    Resumo: A eletrorretinografia (ERG) é um exame oftálmico que permite a captação da atividade eletrofisiológica da retina em resposta a um estímulo luminoso e, portanto é uma ferramenta útil para avaliar o fenômeno da fototransdução no olho. Trata-se de um procedimento seguro uma vez que não é invasivo, mesmo quando necessita de anestesia, como ocorre no caso de sua utilização em animais de companhia. Dois capítulos desta dissertação envolvem estudos experimentais utilizando o exame eletrorret...

  19. Evaluación de Cuatro Protocolos de Anestesia sobre las Variaciones en las Funciones Vitales en la Ovariohisterectomía Canina

    OpenAIRE

    Huayta Huanca, Jhon David; Escuela Profesional de Medicina Veterinaria y Zootecnia, Facultad de Ciencias e Ingenierías Biológicas y Químicas, Universidad Católica de Santa María, Arequipa

    2016-01-01

    El presente estudio tuvo como objetivo la evaluación de los efectos de cuatro protocolos de anestesia sobre las funciones vitales de frecuencia cardiaca, pulso, frecuencia respiratoria, saturación de oxígeno y temperatura corporal en la ovariohisterectomía canina. Se seleccionaron 32 perras adultas (1-8 años), clínicamente sanas, sin distinción de peso ni raza, y clasificados como ASA I (84.4%) o II (15.6%) para ser sometidos a cirugía electiva (no emergencias). Los canes fueron distribuidos ...

  20. Aplicação do monitor Narcotrend® para avaliar a profundidade da anestesia em crianças submetidas à cirurgia cardíaca: estudo prospectivo e controlado

    Directory of Open Access Journals (Sweden)

    Yiyan Jiang

    2013-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Investigar a eficácia clínica, segurança e viabilidade do monitor Narcotrend® para avaliar a profundidade da anestesia em crianças com doença cardíaca congênita (DCC submetidas à cirurgia cardíaca. MÉTODOS: Foram randomicamente selecionadas 80 crianças submetidas à anestesia geral em cirurgia seletiva. As crianças foram divididas em dois grupos de forma aleatória (n = 40 por grupo. No grupo Narcotrend, a profundidade da anestesia foi monitorada com o Narcotrend. No grupo padrão, a profundidade da anestesia foi controlada de acordo com a experiência clínica. A pressão arterial média (PAM e a frequência cardíaca (FC foram determinadas e a dose de fentanil e relaxante muscular e os tempos de recuperação e de extubação foram registrados. RESULTADOS: Em ambos os grupos, os sinais vitais apresentaram-se estáveis durante a cirurgia. No grupo Narcotrend, a PAM e a FC foram mais estáveis, a dose total de fentanil e relaxante muscular significativamente menor e os tempos de recuperação e extubação acentuadamente mais reduzidos em comparação com o grupo padrão. CONCLUSÃO: A aplicação do monitor Narcotrend para medir a profundidade da anestesia foi útil para controlar a profundidade da anestesia em crianças com DCC que receberam anestesia intravenosa total, na qual uma pequena quantidade de narcóticos pode obter a anestesia ideal. Além disso, os tempos de recuperação e extubação foram menores e os efeitos secundários, como sensibilização intraoperatória, puderam ser evitados.

  1. Náuseas y vómitos en anestesia general balanceada ante endovenosa total en colecistectomía laparoscópica. Hospital Nacional Arzobispo Loayza. 2015

    OpenAIRE

    Urday Zagaceta, Erick Ivan

    2015-01-01

    Objetivo: Conocer si la incidencia de náuseas y vómitos posoperatorios en la anestesia general balanceada es mayor que en anestesia general endovenosa total. Método: Se calculó una muestra de 128 de una población de 190 pacientes sometidas a colecistectomías laparoscópicas electivas en el Hospital Nacional Arzobispo Loayza (HNAL). Se incluyeron a pacientes ASA I y II y que sean entre 18 y 60 años. Se excluyeron cirugías de emergencia. Se dividieron en 2 grupos: propofol-remifentanilo y sev...

  2. ANESTESIA BALANCEADA EM LAGARTO-TEIÚ (Tupinambis merianae: RELATO DE CASO

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    Erica Cristina Bueno do Prado Guirro

    2010-06-01

    Full Text Available A tegu lizard tupinambis merianae submitted to osteosynthesison umero received midazolam (0.073mg/kg, i.m. andmorphine (0.224mg/kg, i.m. in pre-medication. The animal wasinduced by ketamine (30mg/kg, i.m. and anesthesia was maintainedwith isofluorane diluted in O2 (1L/Kg/min and supplied byfacial mask, besides local anesthesia with lidocaine 2% withoutadrenaline (5mg/kg. This anesthesia protocol was efficient andsafe to patient.

  3. Elements for successful functional result after surgical treatment of intra-articular distal humeral fractures.

    Science.gov (United States)

    Darabos, Nikica; Bajs, Ivana Dovzak; Sabalić, Srećko; Pavić, Roman; Darabos, Anela; Cengić, Tomislav

    2012-12-01

    Intra-articular distal humeral fractures (DHF) present great challenge to an orthopedic-trauma surgeon. We analyzed the relationship between functional results of DHF surgical treatment and elements that can affect patient recovery. During the 5-year follow-up study, 32 patients were treated for DHF at our Trauma Department, 30 of them by surgical procedure. Functional results of surgical treatment were scored according to the Jupiter criteria. According to the A-O classification of DHF, there were 11 type A fractures, 5 type B fractures and 14 type C fractures. Postoperative complications were infections, neural lesions, inadequate healing, and instability of osteosynthesis. Analysis of functional results in patients with operated C type fractures according to different elements influencing postoperative result revealed correct healing in 74% of patients, which was statistically significantly higher than the percentage of unsatisfactory results (p elements for successful functional recovery.

  4. Combined Intra-Articular and Intravenous Tranexamic Acid Reduces Blood Loss in Total Knee Arthroplasty

    DEFF Research Database (Denmark)

    Nielsen, Christian Skovgaard; Jans, Øivind; Ørsnes, Thue

    2016-01-01

    outcome was the 24-hour calculated blood loss. Secondary outcomes were blood loss on postoperative day 2, thromboembolic complications, and transfusion rate. Blood loss was calculated by hemoglobin differences using the Gross formula. RESULTS: Data on the primary outcome were available for all 60 included......BACKGROUND: In total knee arthroplasty, both intravenous (IV) and intra-articular (IA) administration of tranexamic acid (TXA) have been shown to reduce blood loss in several randomized controlled trials, although routine use of systemic TXA is considerably more common. However, to our knowledge......, the additional benefit of IA administration of TXA when combined with IV administration, without the use of a tourniquet, has not been previously investigated. Thus, the aim of this study was to evaluate whether combined IV and IA administration of TXA reduced total blood loss compared with IV...

  5. Intraarticular findings in the chronically painful shoulder. A study of 32 posttraumatic cases

    DEFF Research Database (Denmark)

    Suder, P.A.; Hougaard, K.; Frich, Lars Henrik

    1994-01-01

    32 consecutive patients suffering from chronic shoulder pain for more than 6 months after a single, nondislocating shoulder trauma were examined clinically and by special radiographs, dynamic sonography, MRI and arthroscopy. Typical complaints were pain during loading, especially during over......, arthroscopic labral resection and open subacromial decompression. In conclusion, patients with chronic posttraumatic shoulder pain have intraarticular injuries, especially tears of the glenoid labrum. History, clinical findings, radiography and sonography are seldom diagnostic. MRI is valuable, particularly...... the head activities. Symptoms of a "dead arm" and instability were also present. Patients with previous dislocations, traumas or radiographic signs of degenerative shoulder lesions were excluded. The patients had a decreased active range of motion and positive signs of apprehension and impingement...

  6. Controversies in the management of intra-articular fractures of distal humerus in adults

    Directory of Open Access Journals (Sweden)

    Sudhir Babhulkar

    2011-01-01

    Full Text Available Background: The surgical approach, type of olecranon osteotomy, method of stabilization of osteotomy, type of fracture stabilization, orthogonal vs parallel plate fixation, need for transposition of ulnar nerve, place for primary total elbow replacement, and type of rehabilitation schedule after surgical fracture treatment are the controversial issues in the treatment of complex intra-articular distal humerus fractures (C2 and C3 in adults. Severe comminution, bone loss, and osteoporosis at the site of distal articular fractures of humerus often lead to unsatisfactory results due to inadequate fixation. We hereby report the outcome of a series of intracondylar fractures of the humerus treated by open reduction and internal fixation and discuss the controversies in light of published literature. Materials and Methods: One hundred and eighty-four patients of intra-articular fractures of distal humerus (C2 and C3 were operated by posterior transolecranon approach between January 1980 and December 2008. Initially, in the first part Chevron intra-articular osteotomy (n=108 was performed out of which 94 have been published in another publication. In later second part (1993 onward, extra-articular olecranon osteotomy (n=76 was routinely performed. Both columns were stably fixed by orthogonal methods; (n=174 however, during the last 2 years, in 10 patients with severe comminution with bone loss, stabilization was achieved by parallel plating. The osteotomy was routinely stabilized by tension band wiring with two parallel K-wires introduced up to the anterior ulnar cortex. The results were evaluated by the staging system of Caja et al. at a minimum follow-up of 2 years. Results: In the first part of the study (n=94, there was delayed union in 4% (n=4, with the fracture taking more than 20 weeks for union. There was delayed union of ulnar osteotomy (n=3 and failure of one tension band wiring, requiring revision. Some loss of motion was seen in 20% of

  7. [Cutaneous atrophy and hypopigmentation secondary to intra-articular corticosteroid injection].

    Science.gov (United States)

    Loarte Pasquel, E P; Cabal García, A A

    2014-04-01

    Epicondylitis is the most common disease of the elbow. It is a tendinitis caused, in most cases, by repetitive motion of the forearm extensor muscles, and belongs to the group of occupational diseases that are related to work activity or sport. Intra-articular injections of glucocorticoids are often used by dermatologists, rheumatologists, orthopaedic surgeons, and primary care due to their ease of administration. However, this procedure has potential side effects. There are a limited number of case reports describing atrophy and hypopigmentation of the skin as a side effect. The general indications for glucocorticoid injections are monofocal and multifocal inflammatory disease, multifocal articular or soft tissue disease. It is more often used in more severe monofocal or multifocal inflammation, failure of drug treatment and/or rehabilitatory when other treatments are contraindicated. Copyright © 2012 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España. All rights reserved.

  8. Intra-articular injections of mesenchymal stem cells for knee osteoarthritis.

    Science.gov (United States)

    Rodríguez-Merchán, Emérito Carlos

    2014-12-01

    Knee osteoarthritis (KOA) represents an enormous societal burden. This review article summarizes the knowledge on the efficacy of using intra-articular injections of mesenchymal stem cells (MSCs) to treat KOA. PubMed (Medline) and the Cochrane Library were searched for literature related to MSC therapy and KOA up until January 31, 2014. The key search terms used were stem cells and knee osteoarthritis. One hundred thirty-five reports were found, but only the 25 fully focused on the topic were used for analysis. Only 3 randomized controlled trials (level II evidence) found pain relief and functional improvement over the short term. The other human studies also reported encouraging results, but their evidence level was very low (IV). Larger randomized controlled trials are needed to support these preliminary encouraging results. The relatively short duration of the studies is also a limitation for the technique at present.

  9. Intraocular Pressure Increases After Intraarticular Knee Injection With Triamcinolone but Not Hyaluronic Acid.

    Science.gov (United States)

    Taliaferro, Kevin; Crawford, Alexander; Jabara, Justin; Lynch, Jonathan; Jung, Edward; Zvirbulis, Raimonds; Banka, Trevor

    2018-03-09

    Intraarticular steroid injections are a common first-line therapy for severe osteoarthritis, which affects an estimated 27 million people in the United States. Although topical, oral, intranasal, and inhalational steroids are known to increase intraocular pressure in some patients, the effect of intraarticular steroid injections on intraocular pressure has not been investigated, to the best of our knowledge. If elevated intraocular pressure is sustained for long periods of time or is of sufficient magnitude acutely, permanent loss of the visual field can occur. How does intraocular pressure change 1 week after an intraarticular knee injection either with triamcinolone acetonide or hyaluronic acid? A nonrandomized, nonblinded prospective cohort study was conducted at an outpatient, ambulatory orthopaedic clinic. This study compared intraocular pressure elevation before and 1 week after intraarticular knee injection of triamcinolone acetonide versus hyaluronic acid for management of primary osteoarthritis of the knee. Patients self-selected to be injected in their knee with either triamcinolone acetonide or hyaluronic acid before being informed of the study. The primary endpoint was intraocular pressure elevation of ≥ 7 mm Hg 1 week after injection. This cutoff is determined as the minimum significant pressure change in the ophthalmology literature recognized as an intermediate responder to steroids. Intraocular pressure was measured using a handheld Tono-Pen® applanation device. This device is frequently used in intraocular pressure measurement in clinical and research settings; 10 sequential measurements are obtained and averaged with a confidence interval. Only measurements with a 95% confidence interval were used. Over a 6-month period, a total of 96 patients were approached to enroll in the study. Sixty-two patients out of 96 approached (65%) agreed. Thirty-one (50%) were injected with triamcinolone and 31 (50%) were injected with hyaluronic acid. Patients

  10. Minimally-invasive treatment of high velocity intra-articular fractures of the distal tibia.

    LENUS (Irish Health Repository)

    Leonard, M

    2012-02-01

    The pilon fracture is a complex injury. The purpose of this study was to evaluate the outcome of minimally invasive techniques in management of these injuries. This was a prospective study of closed AO type C2 and C3 fractures managed by early (<36 hours) minimally invasive surgical intervention and physiotherapist led rehabilitation. Thirty patients with 32 intra-articular distal tibial fractures were treated by the senior surgeon (GK). Our aim was to record the outcome and all complications with a minimum two year follow-up. There were two superficial wound infections. One patient developed a non-union which required a formal open procedure. Another patient was symptomatic from a palpable plate inferiorly. An excellent AOFAS result was obtained in 83% (20\\/24) of the patients. Early minimally invasive reduction and fixation of complex high velocity pilon fractures gave very satisfactory results at a minimum of two years follow-up.

  11. Intra-articular sodium hyaluronate 2 mL versus physiological saline 20 mL versus physiological saline 2 mL for painful knee osteoarthritis

    DEFF Research Database (Denmark)

    Lundsgaard, C; Dufour, N; Fallentin, E

    2008-01-01

    Methodological constraints weaken previous evidence on intra-articular viscosupplementation and physiological saline distention for osteoarthritis. We conducted a randomized, patient- and observer-blind trial to evaluate these interventions in patients with painful knee osteoarthritis....

  12. Intra-articular transplantation of atsttrin-transduced mesenchymal stem cells ameliorate osteoarthritis development.

    Science.gov (United States)

    Xia, Qingqing; Zhu, Shouan; Wu, Yan; Wang, Jiaqiu; Cai, Youzhi; Chen, Pengfei; Li, Jie; Heng, Boon Chin; Ouyang, Hong Wei; Lu, Ping

    2015-05-01

    Osteoarthritis (OA) remains an intractable clinical challenge. Few drugs are available for reversing this degenerative disease, although some promising candidates have performed well in preclinical studies. Tumor necrosis factor α (TNFα) has been identified as a crucial effector modulating OA pathogenesis. This study aimed to investigate the therapeutic effects of Atsttrin, a novel TNFα blocker, on OA treatment. We developed genetically modified mesenchymal stem cells (MSCs) that expressed recombinant Atsttrin (named as MSC-Atsttrin). Expression levels of ADAMTS-5, MMP13, and iNOS of human chondrocytes were analyzed when cocultured with MSC-GFP/Atsttrin. OA animal models were induced by anterior cruciate ligament transection, and MSC-GFP/Atsttrin were injected into the articular cavity 1 week postsurgery. The results showed that MSC-Atsttrin significantly suppressed TNFα-driven up-regulation of matrix proteases and inflammatory factors. Intra-articular injection of MSC-Atsttrin prevented the progression of degenerative changes in the surgically induced OA mouse model. Additionally, levels of detrimental matrix hydrolases were significantly diminished. Compared with nontreated OA samples at 8 weeks postsurgery, the percentages of MMP13- and ADAMTS-5-positive cells were significantly reduced from 91.33% ± 9.87% to 24.33% ± 5.7% (p < .001) and from 91.33% ± 7.1% to 16.67% ± 3.1% (p < .001), respectively. Our results thus indicated that suppression of TNFα activity is an effective strategy for OA treatment and that intra-articular injection of MSCs-Atsttrin could be a promising therapeutic modality. ©AlphaMed Press.

  13. Management of pain on hallux valgus with percutaneous intra-articular Pulse-Dose Radiofrequency.

    Science.gov (United States)

    Masala, Salvatore; Fiori, Roberto; Calabria, Eros; Raguso, Mario; de Vivo, Dominique; Cuzzolino, Alessandro; Simonetti, Giovanni

    2017-01-01

    The purpose of our study was to investigate the role of intra-articular pulse-dose radiofrequency in management of painful hallux valgus refractory to conservative therapies. Between November 2010 and April 2012, 51 patients (15 male, 36 female) with a median age of 71.4 years were included in our clinical trial. Under fluoroscopic guidance we introduced a 22 gauge 10 cm length cannula by a percutaneous access in the first metatarsophalangeal joint and its tip was placed intra-articularly. After removing the spindle, a radiofrequency needle with a 5 mm active tip was introduced. The following parameters were used: 1200 pulses at high voltage (45 V) with 20 msec duration followed by 480 msec silent phases. A great reduction in pain intensity was documented at 1 week, 1 month and 3 months after procedures. Pain intensity increased between 5 and 8 months after treatments, so we performed a second procedure in all patients between 7 months and 9 months since the first treatment. Also in this case we obtained a great reduction of pain intensity in the first 3 months after the procedure. Pain intensity returned at preprocedural values after 9 months after second procedure. No complications were observed. Our experience shows pulse-dose radiofrequency is a safe, repeatable and effective technique for managing patients with symptomatic hallux valgus in the short and medium term. Pulse-dose radiofrequency may improve pain control and quality of life in patients with hallux valgus refractory to conservative therapies. © 2014 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

  14. Factors influencing intra-articular fluid temperature profiles with radiofrequency ablation.

    Science.gov (United States)

    Zoric, Bojan B; Horn, Nils; Braun, Sepp; Millett, Peter J

    2009-10-01

    Radiofrequency ablation devices are being used increasingly in arthroscopic surgery. However, there are concerns that excessive temperatures may damage the articular cartilage. The purpose of this study was to investigate the temperature profiles that occur within the glenohumeral space with the use of one commercially available radiofrequency ablation probe. Ten fresh-frozen human cadaver shoulder specimens were used. Intra-articular temperatures were measured at different time intervals over a two-minute period at a distance of 1, 3, 5, and 10 mm away from the probe. The radiofrequency probe was activated throughout the range of machine power settings, and irrigation fluid flow was varied (no flow, a flow at 60 mm Hg without suction, and a flow at 60 mm Hg with suction). Temperatures deleterious to articular cartilage chondrocytes (i.e., those in excess of 50 degrees C) were seen with an increased duration of application, a decreased distance between the thermometer and the probe, and a decreased irrigation fluid flow rate. The highest recorded irrigation fluid temperature reached >80 degrees C after two minutes in a no-flow setting. The flow rate was found to be the most significant predictor of intra-articular temperature profiles. The various machine power settings had no apparent influence on temperature, meaning that higher probe settings are not necessarily associated with higher temperature profiles. These results demonstrate the importance of the management of the irrigation fluid flow rate across the joint during arthroscopic procedures that involve radiofrequency ablation. Even short intervals of limited flow could lead to supraphysiological temperature profiles and potentially to cartilage damage.

  15. Percutaneous treatment of high-risk patients with intra-articular calcaneus fractures: a case series.

    Science.gov (United States)

    Hammond, Allan William; Crist, Brett D

    2013-11-01

    Diabetics, smokers, patients with open fractures and drug addicts have shown to be at increased risk of having wound complications with traditional calcaneus fixation. The purpose of the study is to examine if high-risk patients with intra-articular calcaneus fractures can be managed safely using percutaneous reduction and fixation by examining a consecutive series of patients treated by the senior author. The treatment group consisted of the senior author's first 17 percutaneously treated calcaneus fractures in high-risk patients. Risk factors included: open fracture, smoking, diabetes and cocaine, alcohol and solvent abuse. Reduction techniques included temporary external fixation, inflatable bone tamps, and arthroscopic assisted reduction manoeuvres. Fixation was accomplished with cannulated 4.5mm screws. Patients were followed up for 3 months minimum to look for wound complications and subsidence. Surgery was performed within 15 days from injury (average 6.7 days). Risk factors included: open fracture 1, smoking 16, diabetes 2, and substance abuse 9. Sanders' classification described: six type 2, nine type 3 and two type 4. Bohlers' angle increased from an average of -1.5° (range -37° to +30) to 25.8° (range 7-36°). There were no wound issues or infections with the calcaneal fixation. Reduction was deemed excellent or good in 14, fair in 2 and poor in 1. Loss of Bohlers' angle of >4° occurred in four cases; in three of these, the patients were non-compliant with weight bearing. High-risk patients with intra-articular calcaneus fractures that meet the criteria for surgical management can be managed with percutaneous surgical techniques with low risk of wound complications. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Primary fusion in worker's compensation intraarticular calcaneus fracture. Prospective study of 169 consecutive cases.

    Science.gov (United States)

    López-Oliva, Felipe; Sánchez-Lorente, Tomás; Fuentes-Sanz, Adela; Forriol, Francisco; Aldomar-Sanz, Yolanda

    2012-12-01

    To study the results of reconstruction and primary fusion in worker's compensation intraarticular calcaneus fractures. We carried out a prospective study of 169 acute intraarticular calcaneus fractures treated by reconstruction and primary fusion with the minimally invasive Vira® system, in severe calcaneus fractures. The evaluation was performed by clinical, radiological and biomechanical analysis. AOFAS score averaged 77.26 points at the end of follow up. Forty-two cases (24.9%) obtained excellent results, 108 (63.9%) good, 12 (7.1%) mild and 7 (4.1%) poor. The improvement in Börder's angle after surgery was significant (p = 0.05) and this did not vary during the follow up. Subtalar arthrodesis was achieved in all cases and only three cases needed bone grafting. Five major post-surgical complications were observed, and one deep infection in a case of open Gustilo Grade III fracture. In the kinetic study, the support time of the operated foot was lower than that of the contralateral foot (p<0.21). The axial force of the heel contact and the single limb support of the operated foot reduced the toe-off axial forces. In the foot with arthrodesis the posterior forces increased (p <0.01). The pressures were lower in the region of the heel and the mid-foot and in the external part of the forefoot, and increased in the big toe. Calcaneal workplace injuries are challenging to treat. Primary subtalar fusion with a minimally invasive method allows rapid recovery for these patients with a satisfactory clinical, functional and radiological outcome. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Navigation system for robot-assisted intra-articular lower-limb fracture surgery.

    Science.gov (United States)

    Dagnino, Giulio; Georgilas, Ioannis; Köhler, Paul; Morad, Samir; Atkins, Roger; Dogramadzi, Sanja

    2016-10-01

    In the surgical treatment for lower-leg intra-articular fractures, the fragments have to be positioned and aligned to reconstruct the fractured bone as precisely as possible, to allow the joint to function correctly again. Standard procedures use 2D radiographs to estimate the desired reduction position of bone fragments. However, optimal correction in a 3D space requires 3D imaging. This paper introduces a new navigation system that uses pre-operative planning based on 3D CT data and intra-operative 3D guidance to virtually reduce lower-limb intra-articular fractures. Physical reduction in the fractures is then performed by our robotic system based on the virtual reduction. 3D models of bone fragments are segmented from CT scan. Fragments are pre-operatively visualized on the screen and virtually manipulated by the surgeon through a dedicated GUI to achieve the virtual reduction in the fracture. Intra-operatively, the actual position of the bone fragments is provided by an optical tracker enabling real-time 3D guidance. The motion commands for the robot connected to the bone fragment are generated, and the fracture physically reduced based on the surgeon's virtual reduction. To test the system, four femur models were fractured to obtain four different distal femur fracture types. Each one of them was subsequently reduced 20 times by a surgeon using our system. The navigation system allowed an orthopaedic surgeon to virtually reduce the fracture with a maximum residual positioning error of [Formula: see text] (translational) and [Formula: see text] (rotational). Correspondent physical reductions resulted in an accuracy of 1.03 ± 0.2 mm and [Formula: see text], when the robot reduced the fracture. Experimental outcome demonstrates the accuracy and effectiveness of the proposed navigation system, presenting a fracture reduction accuracy of about 1 mm and [Formula: see text], and meeting the clinical requirements for distal femur fracture reduction procedures.

  18. Anestesia venosa total com infusão alvo-controlada de remifentanil e propofol para ablação de fibrilação atrial Anestesia venosa total con infusión objeto-controlada de remifentanil y propofol para ablación de la fibrilación atrial Total intravenous anesthesia with target-controlled infusion of remifetanil and propofol for ablation of atrial fibrillation

    OpenAIRE

    Fernando Squeff Nora; Maurício Pimentel; Leandro Ioschpe Zimerman; Eduardo B Saad

    2009-01-01

    JUSTIFICATIVA E OBJETIVOS: A ablação de fibrilação atrial (FA) é um procedimento novo em nosso meio, embora seja comum em outros centros. A escolha da anestesia, monitores e cuidados anestesiológicos para esse procedimento, realizado fora do bloco cirúrgico, não tem sido descrita. O objetivo deste relato foi descrever uma técnica de anestesia para a realização de ablação de FA. RELATO DO CASO: Paciente feminina, 49 anos, 73 kg, 155 cm, ASA II por hipertensão arterial sistêmica. A monitorizaçã...

  19. Isquemia miocárdica silenciosa em pacientes submetidos à prostatectomia transuretral: comparação entre anestesia subaracnóidea e peridural Isquemia miocárdica silenciosa en pacientes sometidos a prostatectomia transuretral: comparación entre anestesia subaracnóidea y peridural Silent myocardial ischaemia in patients undergoing transurethral resection of prostate: comparison of spinal versus epidural anaesthesia

    OpenAIRE

    Parshotam Lal Gautam; Sunil Katyal; Gurpreet Singh Wander; Harpreet Kaur

    2004-01-01

    JUSTIFICATIVA E OBJETIVOS: A isquemia miocárdica silenciosa foi recentemente relacionada ao aumento de morbimortalidade cardíaca peri-operatória. Até 41% dos pacientes com doença coronariana conhecida ou fatores de risco cardíaco, submetidos à cirurgias não cardíacas, apresentaram isquemia peri-operatória. Vários autores compararam técnicas de anestesia regional e geral mas nenhum comparou o impacto de diferentes técnicas de anestesia no neuro-eixo na incidência e duração da isquemia miocárdi...

  20. Anestesia em criança com síndrome de Guillain-Barré após vacina de sarampo: relato de caso Anestesia en un niño con síndrome de Guillain-Barré después de la vacuna de sarampión: relato de caso Anesthesia in Guillain-Barré pediatric patient after measles vaccination: case report

    OpenAIRE

    Deoclécio Tonelli; Paula de Camargo Neves Sacco; Desire Calegari; Gustavo Cimerman; Carolina Mourão dos Santos; Rodrigo Gonzales Farath

    2005-01-01

    JUSTIFICATIVA E OBJETIVOS: A síndrome de Guillain-Barré após vacina de sarampo é rara. O diagnóstico muitas vezes é tardio, o que leva a um aumento da morbidade. O presente relato apresenta um caso avançado e os cuidados especiais exigidos durante a anestesia. RELATO DO CASO: Paciente do sexo masculino, com quatro anos de idade com síndrome de Guillain-Barré desde um ano de idade, foi submetido a gastrostomia sob anestesia geral sem intercorrências, com sevoflurano e sem bloqueadores neuromus...

  1. Periarticular dextrose prolotherapy instead of intra-articular injection for pain and functional improvement in knee osteoarthritis

    Directory of Open Access Journals (Sweden)

    Rezasoltani Z

    2017-05-01

    Full Text Available Zahra Rezasoltani,1 Mehrdad Taheri,2 Morteza Kazempour Mofrad,3 Seyed Amir Mohajerani2 1Department of Physical Medicine and Rehabilitation, AJA University of Medical Sciences, 2Department of Anesthesiology and Pain Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, 3Department of Anesthesiology and Pain Medicine, AJA University of Medical Sciences, Tehran, Iran Background: Osteoarthritis (OA is a degenerative disease that can lead to painful and dysfunctional joints. Prolotherapy involves using injections to produce functional restoration of the soft tissues of the joint. Intra-articular injections are controversial because of the introduction of needles into the articular capsule.Objectives: To compare the effect of periarticular versus intra-articular prolotherapy on pain and disability in patients with knee OA.Study design: Randomized double-blind controlled clinical trial.Setting: Single center, university hospital (Imam Hossein Hospital, Tehran, Iran.Methods: A total of 104 patients with chronic knee OA were enrolled. In the intra-articular group, 8 mL of 10% dextrose and 2 mL of 2% lidocaine were injected. Injections were repeated at 1 and 2 weeks after the first injection. In the periarticular group, 5 mL of 20% dextrose and 5 mL of 1% lidocaine were injected subcutaneously at 4 points in the periarticular area. Pain and disability, as assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC, were recorded at each follow-up visit at 1, 2, 3, 4, and 5 months post-injection.Results: The visual analog scale score was significantly lower in the periarticular compared with the intra-articular group at the 2-, 3-, 4-, and 5-month visits but not at 1 month. Morning stiffness and difficulty in rising from sitting were improved in both groups and were not significantly different in the peri- and intra-articular groups. Pain, joint locking, and limitation scores were all improved in both

  2. Intra-articular viscosupplementation with hylan g-f 20 to treat osteoarthritis of the knee: an evidence-based analysis.

    Science.gov (United States)

    2005-01-01

    randomization, type of control intervention, outcome measures for effectiveness and safety, and length of follow-up. The quality of the studies and level of the evidence was initially scored by one clinical epidemiologist using the Jadad scale and GRADE approach. Level of quality depends on the amount of certainty about the magnitude of effect and is based on study designs, extent of methodological limitations, consistency of results and applicability (i.e. directness) to the Ontario clinical context. The GRADE approach also permits comment on the strength of recommendations resulting from the evidence, based on estimates of the magnitude of effect relative to the magnitude of risk and burden and the level of certainty around these estimates. The quality assessments were subsequently peer-reviewed. The literature search revealed 2 previous health technology assessments, 3 meta-analyses of placebo-controlled trials, 1 Cochrane review and meta-analysis encompassing 18 randomized controlled trials (RCTs) that compared hylan G-F 20 to either placebo or active treatments, 11 RCTs of hylan G-F 20 (all included in the Cochrane review), and 10 observational studies. Given the preponderance of evidence, the Medical Advisory Secretariat's analysis focused on studies with Level 1 evidence of effectiveness (i.e., the meta-analyses of RCTs and the RCTs). Only safety data from the observational studies were included. The authors of the 2 health technology assessments concluded that the data were sparse and poor quality. There was some evidence that hylan G-F 20 delivered a small, clinical benefit at 3 to 6 months after treatment on a magnitude comparable to NSAIDs and intra-articular steroids. Hylan G-F 20 appeared to carry a risk of a local adverse reaction of in the range of 3% to 18% per 100 injections, but there was no apparent risk of a severe adverse event, although the data were limited. Each of the 3 meta-analyses of placebo-controlled trials of intra-articular hyaluronans had only 3

  3. Reconstruction of the anterior cruciate ligament: comparison of analgesia using intrathecal morphine, intra-articular morphine and intra-articular levobupivacaine

    Directory of Open Access Journals (Sweden)

    Leandro Queiroz Pinheiro

    2015-06-01

    Full Text Available OBJECTIVE: To compare the analgesic effect of intra-articular administration of morphine and levobupivacaine (separately or in combination with intrathecal administration of morphine in patients undergoing anterior cruciate ligament (ACL reconstruction using autologous grafts from the patellar tendon.METHODS: This was a retrospective analysis on data gathered from the medical files of 60 patients aged 20 to 50 years who underwent knee video arthroscopy for ACL reconstruction. The patients were divided into four groups of 15 individuals (A, B, C and D according to the agent administered into the joint and around the incision: 20 mL of saline solution with 5 mg of morphine in A; 20 mL of 0.5% levobupivacaine solution in B; 10 mL of solution with 2.5 mg of morphine plus 10 mL of 0.5% levobupivacaine solution in C; and morphine administered intrathecally in D.RESULTS: All the groups presented low pain scores during the first 12 h after the surgery. Groups B and C presented significantly greater pain scores than shown by group D (control, 24 h after the surgery. There was no statistical difference in pain scores between group A and group D.CONCLUSION: The patients in group A presented analgesia comparable to that of the patients in group D, whereas the procedure of group C was no capable of reproducing the analgesic effect observed in group D, as observed 24 h after the surgery. Further studies are needed in order to show the exact mechanism of action, along with the ideal dose and concentration for applying opioids to joints.

  4. O primeiro a utilizar anestesia em cirurgia não foi um dentista. Foi o m édico Crawford Williamson Long El primero en utilizar la anestesia en cirugía no fue un dentista, fue el médico Crawford Williamson Long The first to use surgical anesthesia was not a dentist, but the physician Crawford Williamson Long

    Directory of Open Access Journals (Sweden)

    Almiro dos Reis Júnior

    2006-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A história da descoberta da anestesia continua incompletamente esclarecida em vários de seus aspectos. Mas é fácil definir que Crawford Williamson Long foi o primeiro a utilizar o éter sulfúrico para operar vários pacientes, sem dor, e realizar analgesias obstétricas. A história é uma ponte que liga o passado ao presente e deve ser estudada e entendida desde os seus primeiros pilares. Assim, justifica-se lembrar ou dar a conhecer quem foi Long, um nome certamente pouco conhecido entre nós, e qual a participação dele na descoberta da anestesia. CONTEÚDO: São discorridos porque e como Crawford Williamson Long foi levado a se tornar o primeiro médico a operar sem dor, quatro anos e meio antes de Morton, e o papel que desempenhou numa das maiores descobertas da Medicina. A biografia de Long é narrada, ressaltando-se o seu caráter, a competência, a dedicação, a modéstia, o desprendimento e um certo desapego com relação à conquista da glória. Descrevem-se as circunstâncias que o levaram a não divulgar de imediato sua descoberta. É analisado o envolvimento de Long na discussão pela primazia da descoberta da anestesia e relatado o seu falecimento. As numerosas homenagens recebidas por Long nos EUA e em outros países são citadas. CONCLUSÕES: W. T. G. Morton costuma ser considerado como o autor da descoberta da anestesia geral, sobretudo por ter sido o primeiro a fazer demonstração pública bem-sucedida, em importante hospital de Boston (EUA. Contudo, provou-se que Long foi o primeiro a utilizar a anestesia cirúrgica e é reconhecido em várias regiões de seu país como o pai da anestesia cirúrgica e "o seu descobridor". É necessário, ainda, reverter o fato de ser Long pouco conhecido entre nós e inseri-lo no lugar a que tem direito na história da anestesia geral.JUSTIFICATIVA Y OBJETIVOS: La historia del descubrimiento de la anestesia continúa sin ser completamente aclarada en varios

  5. Anestesia em broncofibroscopia – Estudo randomizado comparando o uso tópico da lidocaína ou em associação com o propofol, o alfentanil ou o midazolam

    Directory of Open Access Journals (Sweden)

    Renato Sotto-Mayor

    2009-07-01

    Full Text Available Resumo: A broncofibroscopia (BFB é efectuada geralmente sob anestesia local, com ou sem sedação.O objectivo deste estudo é escolher o protocolo anestésico utilizado durante a BFB que tenha menos complicações e seja mais bem tolerado.Este estudo prospectivo randomizado analisou 80 doentes que foram submetidos a BFB.Os doentes foram randomizados e divididos em quatro grupos de 20 doentes cada, de acordo com a combinação anestésica utilizada: 200 mg de lidocaína tópica1; 200 mg de lidocaína tópica e propofol, 2 mg/kg2; 200 mg de lidocaína tópica e alfentanil 20 mcg/kg3; ou 200 mg de lidocaína tópica e midazolan 0,005 mg/kg4.Durante o exame foram avaliados diversos scores de acordo com diferentes variáveis e, posteriormente, avaliados os scores mais baixos e o respectivo índice de complicações.Os resultados foram avaliados estatisticamente e a análise revelou que a combinação2 200 mg de lidocaína tópica e propofol, 2 mg/kg, teve uma eficácia superior às outras associações

  6. A phase I/IIa study on intra-articular injection of holmium-166-chitosan complex for the treatment of knee synovitis of rheumatoid arthritis

    Energy Technology Data Exchange (ETDEWEB)

    Song, J.; Suh, C.H.; Park, Y.B.; Lee, S.H.; Lee, S.K. [Dept. of Internal Medicine, Yonsei University College of Medicine, Seoul (Korea); Yoo, N.C. [Dept. of Internal Medicine, Yonsei University College of Medicine, Seoul (Korea); Dept. of Clinical Pharmacology, Yonsei University College of Medicine, Seoul (Korea); Lee, J.D. [Dept. of Nuclear Medicine, Yonsei University College of Medicine, Seoul (Korea); Kim, K.H. [Dept. of Clinical Pharmacology, Yonsei University College of Medicine, Seoul (Korea)

    2001-04-01

    Previous animal studies have established that the intra-articular injection of holmium-166-chitosan complex (DW-166HC) causes effective necrosis of the inflamed synovium with little leakage of radioactivity from the injected joint. Based on these findings, we conducted a phase I/IIa study to examine the biodistribution of DW-166HC and to assess the safety of DW-166HC for the treatment of knee synovitis in patients with rheumatoid arthritis (RA). A total of 16 patients [1 man, 15 women; median age 49 (range 36-65) years] who had RA knee synovitis refractory to disease-modifying antirheumatic drug treatments of >3 months' duration were randomly assigned to three treatment groups with different radiation doses of DW-166HC: 370 MBq (n=6), 555 MBq (n=5) and 740 MBq (n=5). In each treatment group, blood and urine radioactivity were analysed by beta counter and biodistribution of the injected DW-166HC was evaluated using a gamma scan camera. Clinical assessment was done according to three variables (evaluation method): knee joint pain (visual analogue scale), range of motion (goniometry) and joint swelling (circumference of knee joint). The duration of follow-up observation was 3 months. Following the intra-articular injection of DW-166HC, the blood radioactivity was little changed from the baseline measurement and the accumulated radioactivity excreted in urine was minimal. Gamma scan study indicated that most of the injected radiochemical was localized within the injected joint cavity, and the extra-articular leakage was negligible at 24 h after the injection: brain, 0.3%; lung, 0.6%; abdomen, 0.7%; and pelvis, 0.8%. Major adverse events were transient post-injection knee joint pain and swelling. These results suggest that DW-166HC might be a safe agent for radiation synovectomy, particularly for the treatment of knee synovitis of RA, and further trials in a larger patient population are warranted to evaluate the therapeutic efficacy of DW-166HC. (orig.)

  7. The "joint-elevation" calcaneus fracture: a rare variant of the intra-articular calcaneus fracture-dislocation.

    Science.gov (United States)

    Miller, Timothy J; Kwon, John Y

    2015-04-01

    Calcaneus fractures are the most commonly fractured tarsal bone with approximately 75% being intra-articular in nature. Böhler's angle has been found to be reliable and prognostic, and it has been used as a proxy for joint depression and articular involvement. It often guides the need for advanced imaging and/or operative intervention. We describe a rare variant of intra-articular calcaneus fracture-dislocation that results in elevation of a portion of the posterior facet above the posterior talus and a seemingly normal or increased Böhler's angle, which we call the "joint-elevation" calcaneus fracture. Orthopaedic surgeons should be aware of this previously undescribed variant in order to avoid inappropriate treatment or misdiagnosis. Therapeutic Level IV: Case Series. © 2014 The Author(s).

  8. Pneumoencéfalo após anestesia peridural: relato de caso

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    Angélica de Fátima de Assunção Braga

    2001-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O bloqueio peridural constitui técnica utilizada para alívio da dor durante o trabalho de parto. Apesar das vantagens, não é isenta de complicações, como, por exemplo, o pneumoencéfalo. O objetivo deste relato é apresentar um caso de pneumoencéfalo iatrogênico, diagnosticado após bloqueio peridural, com punção acidental de duramáter. RELATO DO CASO: Paciente de 16 anos, estado físico ASA I, sem antecedentes anestésicos, submetida a bloqueio peridural contínuo para analgesia de parto. Após várias tentativas de punções no espaço L3-L4, ocorreu punção acidental de duramáter. Optou-se por nova punção peridural em L2-L3, sem sucesso. Foi tentada outra punção em L3-L4, e após identificação do espaço peridural empregando-se a técnica da perda da resistência com ar, injetou-se o anestésico local e fentanil, seguido de passagem do cateter. Após 20 minutos da instalação do bloqueio, ocorreu sofrimento fetal, com indicação de cesariana, sendo administrada dose complementar de anestésico local pelo cateter. A paciente permaneceu hemodinamicamente estável e consciente durante a cirurgia, com lenta recuperação do bloqueio motor (14 h. No pós-operatório, apresentou dois episódios de crise convulsiva, com intervalo de 12 horas entre eles, que reverteram espontaneamente. A avaliação neurológica era normal e a tomografia computadorizada revelou imagem com densidade de ar compatível com pneumoencéfalo. A paciente teve alta três dias após, sem seqüelas. CONCLUSÕES: O caso confirma a possibilidade de se causar pneumoencéfalo iatrogênico durante a realização de bloqueio peridural, empregando-se a técnica da perda de resistência ao ar para a identificação do espaço peridural. Na presença de sinais e sintomas de irritação meníngea, a tomografia computadorizada é o meio diagnóstico recomendado para o diagnóstico diferencial entre pneumoencéfalo e as demais causas.

  9. 18 month observational study on efficacy of intraarticular hyaluronic acid (Hylan G-F 20 injections under ultrasound guidance in hip osteoarthritis

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    Cristiano Padalino

    2011-09-01

    Full Text Available Objective: To evaluate the efficacy and the tolerability of viscosupplementation (VS with hyaluronic acid (Hylan GF 20 in a cohort of 36 patients affected by hip osteoarthritis through a 18 months follow-up. Methods: Viscosupplementation was performed with an anteriorsagittal approach, under ultrasound guidance. 36 patients were administered hyaluronic acid intraarticularly in the hip, with a unique injection of Hylan G-F20, which could be repeated after at least 3 months. Treatment efficacy was assessed by functional index WOMAC, pain evaluation on a visual analogue scale and NSAID consumption. All such parameters were recorded at the time of the first injection and then 3, 6, 9, 12 and 18 months later. Results: Statistically significant reduction of all parameters was observed three months after the injection, and was still maintained at the timepoints 6, 9, 12 and 18 months. No local side effects have been observed, nor systemic complications. Conclusions: Our data show that viscosupplementation is a promising approach for hip osteoarthritis, providing beneficial effects in a long-tern follow up. Yet, the topic deserves further and wider studies, so to define the number of injections to administer and suggest a fit interval between subsequent injections.

  10. Anestesia general y analgesia para la resección de nódulo hepático en perro con enfermedad de Cushing y diabético: caso clínico

    OpenAIRE

    Costa, Margarida; Alexandre, Nuno; Pinho, Leonor; Martín, Maria; Gracia, Monica; Celdrán, Diego; Lima, Juan; Sánchez, Francisco

    2010-01-01

    O objectivo deste trabalho foi proporcionar uma anestesia inalatória e analgesia multimodal segura e eficaz num caso clínico de excisão cirurgica de um nódulo hepático num cão diabético, com insuficiência cardiaca e sindrome de cushing.

  11. Intraarticular application of superparamagnetic nanoparticles and their uptake by synovial membrane-an experimental study in sheep

    Energy Technology Data Exchange (ETDEWEB)

    Schulze, Katja [Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich (Switzerland); Koch, Annette [Department of Chemistry and Applied BioSciences, Swiss Federal Institute of Technology Zurich (ETH Zurich), Winterthurerstrasse 190, 8057 Zurich (Switzerland); Schoepf, Bernhard [Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich (Switzerland); Petri, Alke [Laboratory of Powder Technology, Swiss Federal Institute of Technology (EPFL), Lausanne (Switzerland); Steitz, Benedikt [Laboratory of Powder Technology, Swiss Federal Institute of Technology (EPFL), Lausanne (Switzerland); Chastellain, Mathieu [Laboratory of Powder Technology, Swiss Federal Institute of Technology (EPFL), Lausanne (Switzerland); Hofmann, Margarethe [MatSearch, Chemin Jean Pavillard 14, 1009 Pully (Switzerland); Hofmann, Heinrich [Laboratory of Powder Technology, Swiss Federal Institute of Technology (EPFL), Lausanne (Switzerland); Rechenberg, Brigitte von [Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich (Switzerland)]. E-mail: bvonrechenberg@vetclinics.unizh.ch

    2005-05-15

    A superparamagnetic iron oxide nanoparticle, coated with polyvinyl alcohol (PVA-SPION) and its fluorescently functionalized analogue (amino-PVA-Cy3.5-SPION) were compared in vivo as proof of principle for future use in magnetic drug targeting in inflammatory joint diseases. They were injected either intraarticularly or periarticularly and their uptake by cells of the synovial membrane was evaluated. Uptake was completed in 48 h and was enforced by an extracorporally applied magnet.

  12. Optimal dose of intra-articular corticosteroids for adhesive capsulitis: a randomized, triple-blind, placebo-controlled trial.

    Science.gov (United States)

    Yoon, Seung-Hyun; Lee, Hyun Young; Lee, Hyun Jung; Kwack, Kyu-Sung

    2013-05-01

    Intra-articular corticosteroid injection is a commonly used therapy for adhesive capsulitis, but there are only few studies that compare the efficacy of corticosteroids according to different doses. To determine whether intra-articular injections with a high-dose corticosteroid improves pain and function in patients with adhesive capsulitis better than a low dose or a placebo. Randomized controlled clinical trial; Level of evidence, 1. Participants (n = 53) with primary adhesive capsulitis in the freezing stage were randomly assigned to receive ultrasound-guided intra-articular injections with 40 mg triamcinolone acetonide (high-dose group, n = 20), 20 mg triamcinolone acetonide (low-dose group, n = 20), or placebo (n = 13). After a single injection, participants were all instructed to carry out a home exercise program. The outcome measures included the Shoulder Pain and Disability Index (SPADI), visual analog scale (VAS) for average shoulder pain level, and passive range of motion including flexion, abduction, extension, external rotation, and internal rotation before treatment and at weeks 1, 3, 6, and 12 after treatment. There were no significant differences in demographic and clinical characteristics at baseline between the 3 groups. Repeated-measures analysis of variance and post hoc tests showed improvement in SPADI and VAS scores and in flexion, abduction, and internal rotation especially for the low- and high-dose groups compared with the placebo. Yet, no significant difference was found between the 2 different corticosteroid dose groups. We assessed the efficacy of corticosteroid injections according to 2 different doses that are most widely used in intra-articular injections for adhesive capsulitis. This study shows that there were no significant differences between the high- and low-dose corticosteroid groups, indicating the preferred use of a low dose in the initial stage.

  13. Body mass index and active range of motion exercise treatment after intra-articular injection in adhesive capsulitis.

    Science.gov (United States)

    Lin, Hsi-Hsien; Huang, Tung-Fu; Ma, Hsiao-Li; Liu, Chien-Lin

    2013-04-01

    Adhesive capsulitis is commonly associated with medical diseases such as diabetes mellitus, hyperthyroidism, and obesity. Intra-articular injection has been used to speed recovery and relieve pain associated with frozen shoulder. In this study, we evaluated and compared the effects of an intra-articular injection of corticosteroid and lidocaine in the treatment of primary adhesive capsulitis in overweight and normal-weight patients. This is a prospective clinical study of patients with adhesive capsulitis, in which the main treatment strategy was an intra-articular injection of corticosteroid (3 mL) and lidocaine (3 mL). Active range of motion exercise was initiated immediately after the injection and performed four times daily. The evaluation included the recording of a detailed medical and orthopedic history, and the assessment of pain and function by determining the Constant score at baseline (before injection) and every 2 weeks thereafter. Patients were classified as normal weight (body mass index [BMI] adhesive capsulitis between 2010 and 2012. In the normal-weight group, the mean Constant score increased from 35.4 to 74.6 after 8 weeks, whereas in the overweight group, the mean Constant score increased from 32.0 to 47.2. There was a significant difference in the mean Constant score between the normal-weight and overweight groups at 8 weeks. Active range of motion exercise after an intra-articular injection of corticosteroid and lidocaine improved pain and functional outcome at 8 weeks in normal-weight (BMI adhesive capsulitis. Manipulation under anesthesia may be considered a priority in overweight patients. Copyright © 2013. Published by Elsevier B.V.

  14. Randomized controlled trial for efficacy of intra-articular injection for adhesive capsulitis: ultrasonography-guided versus blind technique.

    Science.gov (United States)

    Lee, Hong-Jae; Lim, Kil-Byung; Kim, Dug-Young; Lee, Kyung-Tae

    2009-12-01

    Lee H-J, Lim K-B, Kim D-Y, Lee K-T. Randomized controlled trial for efficacy of intra-articular injection for adhesive capsulitis: ultrasonography-guided versus blind technique. To evaluate the clinical effect of ultrasonography (US)-guided intra-articular injections compared with a blind (unguided) technique for the treatment of adhesive capsulitis. Randomized controlled trial. Outpatient rehabilitation clinic. Patients (N=43) diagnosed as having adhesive capsulitis after clinical examinations and radiologic and ultrasonographic study. Under either US-guided or a blind technique, patients received a 20-mg intra-articular injection of triamcinolone mixed with 1.5mL 2% lidocaine and 4mL normal saline in the first week followed by 5 weekly injections of sodium hyaluronate. A visual analog scale for pain intensity, range of motion (ROM) of the shoulder (flexion, abduction, external rotation, and internal rotation), and general shoulder function during daily activities at preinjection as a baseline and then every week after injection for 6 weeks for each patient. Twenty patients out of 22 in the blind injection group and 20 out of 21 in the US-guided group finished the entire 6-week study period. The improvement in pain intensity, ROM, and shoulder function score was significantly greater in the US-guided injection group than in the blind injection group by the second week postinjection (Padhesive capsulitis and may deliver clinical benefits during the first few weeks of treatment. This finding suggests that the improved targeting to the intra-articular space by using US can result in better treatment of adhesive capsulitis.

  15. Evaluation of intra-articular injection of autologous platelet lysate (PL) in horses with osteoarthritis of the distal interphalangeal joint.

    Science.gov (United States)

    Tyrnenopoulou, Panagiota; Diakakis, Nikolaos; Karayannopoulou, Maria; Savvas, Ioannis; Koliakos, Georgios

    2016-06-01

    Regenerative medicine has become one of the most promising therapies of equine osteoarthritis. Platelet lysate (PL) is rich in bioactive proteins and growth factors that play a crucial role in tissue healing. To evaluate the efficacy of intra-articularly injected autologous PL in equine athletes with naturally occurring osteoarthritis. Fifteen warmblood geldings aged 8-19 years with osteoarthritis of the distal interphalangeal joint were included in this study. They were randomly divided into two groups; 10 horses received intra-articular injections of PL and 5 of normal saline (controls). Before treatment, platelet-derived growth factor (PDGF) levels in basal plasma and prepared PL were estimated. Each joint was injected twice within a three-week period. Lameness was evaluated using the American Association of Equine Practitioners grading system, before treatment and 10 days after each intra-articular injection. Horses were examined fortnightly for one year. Radiographic examination was performed six months post-treatment. The generalized estimating equation test was used for statistical analysis. Acceptable levels of PDGF were detected in PLs (mean ± SD: 258.0 ± 52.3 pg/ml). The majority of horses (9/10) responded positively to PL treatment presenting lower lameness grades (p < 0.0005) compared to controls 10 days after the second injection, and returned to normal athletic activity. Radiographs revealed no changes in osteoarthritis lesions six months after treatment. One year post-injections, however, all horses relapsed to their initial degree of lameness. Intra-articularly injected autologous PL is an efficient method for temporarily managing osteoarthritis of the distal interphalangeal joint in athletic horses.

  16. Gait Changes Vary Among Horses with Naturally Occurring Osteoarthritis Following Intra-articular Administration of Autologous Platelet Rich Plasma

    Directory of Open Access Journals (Sweden)

    Mustajab Hussain Mirza

    2016-04-01

    Full Text Available Mechanisms to reduce lameness associated with osteoarthritis (OA are vital to equine health and performance. This study was designed to quantify response to autologous, intra-articular platelet-rich plasma (PRP in horses with OA. Kinetic gait analysis was performed on 12 horses with unilateral forelimb lameness and OA in the same limb before and after intra-articular anesthesia (IAA. Radiographs and kinetic data were obtained before, 6 and 16 weeks after PRP administration to same joint 4 weeks after IAA. Statistical evaluations included filtration effect on platelet concentration, relationship between kinetic variable changes after IAA versus PRP in the affected limb, and associations between response to PRP and response to IAA, platelet concentration and radiographic OA. A positive response to IAA or PRP was defined as ≥5% improvement in peak vertical force, vertical impulse or breaking impulse of the affected limb. Out of 10 horses that responded to IAA, 4 responded to PRP at both time points and 2 responded at one. Of 2 horses that did not respond to IAA, one responded to PRP at both time points. Filtration increased platelet concentration significantly. The relationship between kinetic variable alterations of the affected limb after IAA and PRP was not significant, and response to PRP was not associated with response to IAA, platelet concentration or radiographic OA. Changes in kinetic variables following IAA in joints with naturally occurring OA provide a custom standard to assess intra-articular therapy. Kinetic gait changes after intra-articular PRP are variable in horses with moderate to severe forelimb OA.

  17. Anestesia para paciente portador da equência de moebius: relato de caso Anestesia para Paciente Portador de la Secuencia de Moebius: relato de Caso Anesthesia in a patient with moebius sequence: case report

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    Adriano Bechara de Souza Hobaika

    2009-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A sequência de Moebius (SM é uma rara paralisia do VI e VII nervos cranianos. Alterações craniofaciais estão presentes em aproximadamente 90% destes pacientes, o que pode tornar a intubação traqueal muito difícil. RELATO DO CASO: Paciente do sexo masculino, 2 anos e 5 meses, portador de SM, submetido à broncoscopia flexível para avaliação de laringotraqueomalácia. Comorbidades: crises de broncoespasmo e comunicação interventricular. Realizou-se indução anestésica com sevoflurano em O2 a 100% e venóclise. Introduziu-se máscara laríngea AMBU® número 2,5 e o fibrobroncoscópio foi introduzido através da mesma. O procedimento foi realizado sem complicações e a broncoscopia revelou-se normal. O paciente recebeu alta para casa após duas horas. CONCLUSÕES: O controle das vias aéreas é o grande desafio nestes pacientes, havendo relato de falha ou dificuldade de intubação em 13 pacientes de uma série de 41 casos analisados. Micrognatia, retrognatia, hipoplasia mandibular e fenda palatina são algumas características destes pacientes. Em outra grande série com 106 anestesias em pacientes com SM há descrição do uso da máscara laríngea em um caso. Parece não haver contra-indicação a realizar o procedimento em regime ambulatorial. Há relato de aspiração pulmonar e obstrução respiratória na sala de recuperação devido à dificuldade em deglutir e eliminar as secreções da boca e recomenda-se administrar antisialogogos.JUSTIFICATIVA Y OBJETIVOS: La secuencia de Moebius (SM es una rara parálisis del VI y VII nervios cranianos. Las alteraciones craneofaciales están presentes en aproximadamente un 90% de esos pacientes, lo que puede hacer con que la intubación traqueal sea muy difícil. RELATO DEL CASO: Paciente del sexo masculino, 2 años y 5 meses, portador de SM, sometido a la broncoscopia flexible para la evaluación de laringotraqueomalacia. Comorbidades: crisis de broncoespasmo

  18. Anestesia no cardiovascular en el adulto con cardiopatía congénita cianótica

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    Lincoln de la Parte Pérez

    2004-03-01

    Full Text Available Como resultado del progreso en el diagnóstico y tratamiento de las cardiopatías congénitas, la esperanza de vida aumenta considerablemente en nuestro medio. Consecuentemente más niños crecen hasta convertirse en adultos y un grupo de ellos serán sometidos a procedimientos quirúrgicos no cardiovasculares. Estos pacientes constituyen un reto para los anestesiólogos por 3 motivos: 1. Existe una gran variedad de variedades anatómicas y fisiológicas; 2. La capacidad cardiovascular y pulmonar están afectadas de forma significativa y 3. Existe poca información disponible acerca del manejo anestésico de estos pacientes. Las operaciones no cardiovasculares en los pacientes que padecen o han sido operados por padecer cardiopatías congénitas, deben realizarse si es posible, en hospitales de primer nivel y el anestesiólogo responsable debe tener experiencia previa en anestesia cardiovascular pediátrica o por lo menos acceso directo a consulta con un anestesiólogo cardiovascular pediátrico. Se presenta una revisión bibliográfica actualizada sobre el manejo anestésico de los pacientes que padecen de cardiopatías congénitas cianóticas sometidos a procedimientos quirúrgicos no cardiovascularesAs a result of the progress attained in the diagnosis and treatment of congenital heart diseases, life expectancy increases considerably in our environment. Consequently, more children grow up until becoming adults and some of them will undergo noncardiovascular surgical procedures. These patients are a challenge for anesthesiologists for 3 reasons: 1. There is a great number of anatomical and physiological varieties; 2. The cardiovascular and pulmonary capacities are significantly affected; 3. There is little information available about the anesthetic management of these patients. The noncardiovascular operations in patients suffering from heart diseases or that have undergone surgery due to congenital heart diseases, should be performed if

  19. Atelectasia pulmonar em cães durante anestesia geral Pulmonary atelectasis in dogs during general anesthesia

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    Patrícia Cristina Ferro Lopes

    2010-02-01

    Full Text Available A pressão intrapleural normalmente é menor que a pressão intrapulmonar. Consequentemente , os pulmões tendem ao colapso e se retraem, afastando-se da parede torácica. No início do século XX, Pasteur descreveu a atelectasia pulmonar, que ocorre com frequência durante a indução anestésica, persiste no período pós-operatório e pode contribuir de maneira significativa para a morbidade e o aumento nos gastos com medicamentos. Em medicina veterinária, no entanto, a atelectasia não é frequentemente diagnosticada, apesar de que isso não implica afirmar que tal afecção não ocorra, visto que existem relatos do desenvolvimento desse quadro em cães e em outras espécies. No contexto da anestesia geral, essa complicação pulmonar pode ser encontrada em animais que respiram 80 a 100% de oxigênio. A partir dessas informações, torna-se necessário que o profissional da anestesiologia veterinária obtenha conhecimentos complementares sobre o tema. Com este trabalho, objetivou-se descrever alguns dos mecanismos da atelectasia e seus pontos relevantes, de modo a familiarizar os profissionais quanto aos pormenores dessa importante, e nem sempre bem compreendida, alteração fisiológica respiratória.Pleural pressure is usually lower than pulmonary pressure. Therefore, the lungs tend to collapse and increase its distance from thoracic walls. At the beginning of 20th century, Pasteur described the pulmonary atelectasis, which develops during induction of anesthesia and persists to the postoperative period. It can contribute significantly to morbidity and to increase the medical expenses. In veterinary medicine, pulmonary atelectasis is not frequently diagnosed, which doesn't rule out the occurrence of this disease, since there are reports of atelectsasis in dogs. This pulmonary complication can be found in animals that breathe 80% to 100% oxygen in anesthetic procedures. Based on this information, the veterinary anesthesiologist is required

  20. Anestesia no cardiovascular en el paciente con cardiopatía congénita y flujo pulmonar aumentado

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    Lincoln de la Parte Pérez

    2003-12-01

    Full Text Available Los lactantes y dentro de éstos los de menor edad y peso corporal, que padecen de cardiopatías congénitas con flujo pulmonar aumentado y son sometidos a anestesia para procedimientos quirúrgicos no cardiovasculares, tienen un gran riesgo anestésico, por lo que es necesario enfatizar que estos pacientes presentan habitualmente múltiples alteraciones anatómicas y de la fisiología cardiovascular con repercusión en diferentes órganos y sistemas, diversas enfermedades asociadas que empeoran el pronóstico y necesitan frecuentemente tratamiento médico con digitálicos, diuréticos y fármacos vasoactivos desde muy temprano, de modo que la evaluación preoperatoria, incluidas las investigaciones no invasivas, deben ser realizadas por cardiólogos experimentados y cuando se programan para procedimientos quirúrgicos, deben ser remitidos para un centro con recursos y la experiencia necesaria en el manejo de los pacientes con cardiopatías congénitas. Se presenta una revisión bibliográfica actualizada sobre el manejo anestésico de estos pacientes.Infants and among them the youngest and with the least body weight suffering from congenital heart diseases with increased pulmonary flow and who receive anesthesia to undergo noncardiovascular surgical procedures, are at a great anesthetic risk . That's why, it is necessary to make emphasis on the fact that these patients usually present multiple anatomical alterations and cardiovascular physiology disorders with repercussion on different organs and systems, diverse associated diseases that worsen the prognosis, and that they frequently need medical treatment with digitalis, diuretics and vasoactive drugs very early. Taking this into account, the preoperative evaluation, including non-invasive research should be carried out by experienced cardiologists and when they are scheduled for surgical procedures, they should be referred to a center with resources and the necessary experience in the

  1. Alterações transitórias do exame neurológico durante o despertar da anestesia com enflurano, isoflurano ou sevoflurano Alteraciones transitorias del examen neurológico durante el despertar de la anestesia con enflurano, isoflurano o sevoflurano Transient neurological changes during emergence from enflurane, isoflurane or sevoflurane anesthesia

    Directory of Open Access Journals (Sweden)

    Luiz Fernando Soares

    2001-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Anormalidades transitórias do exame neurológico ocorrem durante o despertar da anestesia com halotano, enflurano e isoflurano. Pouco se conhece sobre a ocorrência de anormalidades do exame neurológico durante a recuperação da anestesia com sevoflurano. Este estudo teve como objetivo comparar a prevalência de tais achados durante a recuperação da anestesia com enflurano (Grupo E, isoflurano (Grupo I e sevoflurano (Grupo S. MÉTODO: Foram estudados 44 pacientes que receberam anestesia com enflurano, isoflurano ou sevoflurano em N2O a 50%. Foram anotados antes da indução, imediatamente após a cessação da administração do anestésico e 5, 10, 15, 20, 30 e 40 minutos após: temperatura timpânica, nível de consciência, tônus muscular, reflexos pupilar, ciliar, bicipital, patelar e cutâneo-plantar, bem como a ocorrência de calafrios. RESULTADOS: As respostas dos reflexos pupilar, ciliar, patelar e cutâneo-plantar correlacionaram-se com o nível de consciência. Os grupos não diferiram quanto à prevalência de hipertonia muscular, hiperreflexia bicipital, clônus plantar e resposta extensora cutâneo-plantar. Hiperreflexia patelar foi mais freqüente no grupo do enflurano do que no grupo do isoflurano. Calafrios foram mais freqüentes nos grupos E e I do que no grupo do sevoflurano. A temperatura timpânica não diferiu entre os pacientes que apresentaram ou não calafrios. CONCLUSÕES: Alterações reversíveis do exame neurológico podem estar presentes por até 40 minutos durante a recuperação da anestesia com enflurano, isoflurano ou sevoflurano.JUSTIFICATIVA Y OBJETIVOS: Anormalidades transitorias del examen neurológico ocurren durante el despertar de la anestesia con halotano, enflurano e isoflurano. Poco se conoce sobre la ocurrencia de anormalidades del examen neurológico durante la recuperación de la anestesia con sevoflurano. Este estudio tuvo como objetivo comparar la prevalencia de tal

  2. Analgesic Effect of Intra-Articular Injection of Temperature-Responsive Hydrogel Containing Bupivacaine on Osteoarthritic Pain in Rats

    Science.gov (United States)

    Kim, Taemin; Seol, Dong Rim; Hahm, Suk-Chan; Ko, Cheolwoong; Kim, Eun-Hye; Chun, Keyoungjin; Kim, Junesun; Lim, Tae-Hong

    2015-01-01

    The present study examined the analgesic effects of slow-releasing bupivacaine from hydrogel on chronic arthritic pain in rats. Osteoarthritis (OA) was induced by monosodium iodoacetate (MIA) injection into the right knee joint. Hydrogel (HG: 20, 30, and 50 μL) and temperature-sensitive hydrogel containing bupivacaine (T-gel: 20, 30, and 50 μL) were injected intra-articularly 14 days after MIA injection. Behavioral tests were conducted. The rats showed a significant decrease in weight load and paw withdrawal threshold (PWT). Intra-articular 0.5% bupivacaine (10 and 20 μL) significantly reversed MIA-induced decreased PWT, with no effect on weight load. In normal rats, hydrogel did not produce significant changes in PWT but at 30 and 50 μL slightly decreased weight bearing; T-gel did not cause any changes in both the weight load and PWT. In OA rats, T-gel at 20 μL had a significant analgesic effect for 2 days, even though T-gel at 50 μL further reduced the weight load, demonstrating that intra-articular T-gel (20 μL) has long-lasting analgesic effects in OA rats. Thus, T-gel designed to deliver analgesics into the joint cavity could be an effective therapeutic tool in the clinical setting. PMID:26881207

  3. Comparative Study of the Use of Intra-articular and Systemic Meloxicam to Control Experimentally Induced Osteoarthritis in Rabbit Knees

    Directory of Open Access Journals (Sweden)

    Valeria Trombini Vidotto

    2013-12-01

    Full Text Available Objective: This study aimed to evaluate morphologic changes, as well as chondroprotective and intra-articular effects of meloxicam on joint repair in rabbits induced by experimental trochleoplasty, minimizing possible adverse side effects. Methods: Thirty-five rabbits were divided into four groups: the control group, which did not undergo surgery, and operated groups, which used different ways of administering the anti-inflammatory agent: systemic, 0.2 mg/kg; intra-articular, 0.5 mg/kg; positive group control, without meloxicam. Each operated group was divided according to the periods of 7 or 30 days evaluation after surgery. Results: Regarding macroscopic and histological evaluation of cartilage, after 30 days, most animals showed almost complete joint repair, the presence of few or no inflammatory cells; whereas part of the animals treated with meloxicam presented necrosis in the trochlear ridge and absence of inflammatory cells after 7 days. In positive control group, it was observed moderate inflammation and connective tissue proliferation. None of the animals in the operated groups showed irregularities 30 days after surgery. Conclusion: Either intra-articular or systemic, meloxicam revealed to be favorable to be used for joint repair and control of inflammatory reaction.

  4. Pharmacokinetics of betamethasone in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.

    Science.gov (United States)

    Knych, Heather K; Stanley, Scott D; Harrison, Linda M; Mckemie, Daniel S

    2017-09-01

    The use of corticosteroids, such as betamethasone, in performance horses is tightly regulated. The objective of the current study was to describe the plasma pharmacokinetics of betamethasone as well as time-related urine and synovial fluid concentrations following intra-articular administration to horses. Twelve racing-fit adult Thoroughbred horses received a single intra-articular administration (9 mg) of a betamethasone sodium phosphate and betamethasone acetate injectable suspension into the right antebrachiocarpal joint. Blood, urine, and synovial fluid samples were collected prior to and at various times up to 21 days post drug administration. All samples were analyzed using tandem liquid chromatography-mass spectrometry. Plasma data were analyzed using compartmental pharmacokinetic modeling. Maximum measured plasma betamethasone concentrations were 3.97 ± 0.23 ng/mL at 1.45 ± 0.20 h. The plasma elimination half-life was 7.48 ± 0.39 h. Betamethasone concentrations were below the limit of detection in all horses by 96 h and 7 days in plasma and urine, respectively. Betamethasone fell below the limit of detection in the right antebrachiocarpal joint between 14 and 21 days. Results of this study provide information that can be used to regulate the use of intra-articular betamethasone in the horse. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  5. [Surgery for degenerative spondylolisthesis of the lumbar spine using intra-articular fusion. A prospective study].

    Science.gov (United States)

    Hrabálek, L; Wanek, T; Adamus, M; Cecháková, E; Buřval, S; Langová, K; Vaverka, M

    2014-01-01

    The aim of the study is to present our surgical method of treating degenerative spondylolisthesis, which includes radical bilateral laminectomy to relieve compression on the spinal cord, transpedicular fixation of the segment and arthrodesis by bilateral intra-articular fusion. This surgery was indicated in patients with grade I or grade II of degenerative sponylolisthesis with a 4-mm or more slippage. Our prospectively studied group consisted of 46 patients (17 men, 29 women; average age, 64.2 years; range, 39-84 years). Before surgery and at 1 year after the procedure, the intensity of axial pain and that of radicular pain were each assessed using the visual Analogue Scale (VAS). Difficulty in performing daily living activities was measured by the Oswestry Disability Index (ODI). The surgical procedure included laminectomy, partial medial facetectomy, foraminotomy to relieve pressure on the spinal nerve roots and transpedicular fixation to provide stability. Using a cutter, cartilage was separated off the cortical bone and, in order to facilitate fusion, bone cavities thus produced were filed with corticospongious grafts harvested from the removed vertebral arch with Kerrison forceps. At 1-year follow-up, dynamic X-ray was used to evaluate spine alignment and, on a CT scan, the degree of intra-articular fusion was assessed. Fusion was achieved when bone density measurement showed more than 350 Hounsfield Units (HU). For the measurements, the authors used their own modified method by means of a Region of Interest (ROI) analysis. The clinical and radiographic results were statistically evaluated. At 1 year after surgery, lumbar flexion-extension bending X-ray films revealed stability of the treated segments in all patients (100%). CT examination showed bone density higher than 350 HU at both joints, i.e., complete bone fusion, also in all 46 patients. The mean post-operative ODI score was significantly lower than its mean pre-operative value (23.6 vs 55.4), which

  6. Benzocaine hydrochloride anesthesia in carp (Cyprinus carpio / Cloridrato de benzocaína na anestesia de carpas (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Marco Antonio da Rocha

    2008-08-01

    Full Text Available Fish anesthesia is indicated to allow the accomplishment of several procedures such as biometry, tagging, transportation, physical examination, surgical procedures, and reproductive management. The doses of benzocaine in the carp anesthesia (Cyprinus carpio were determined, carrying through six phases with 40 fish each. The average weight of carps in each phase was of 147.45±7.99g, 173.32±9.15g, 191.26±14.05g, 269.84±19.24g, 285.25±17.97g, and 300.91±16.45g. In each phase, fish had been captured and placed in four containers each one with different concentrations of benzocaine (100, 140, 180 and 220 mg/L respectively. The induction time (IT was registered for each fish and after that the anesthetic induction biometry was performed. In each phase the minimal dose of benzocaine was calculated using the Linear Response Plateau (LRP, in a model that included dose and IT. The LRP was calculated for each phase: 125.79mg/L in 114.33s, 155.68mg/L in 115.75s, 145.33mg/L in 102.52s, 149.50mg/L in 140.53s, 166.42mg/L in 116.15s, and 158.34mg/L in 102.00s. The optimal dose was related with the weight, resulting in the equation: dose=114.230+0.158 x weight (r2=0.53. The equation shows that an increase in the weight in 1g corresponds to an increase of 0.158 mg/L in the dose of benzocaine hydrochloride for carps.A anestesia em peixes é indicada para permitir a realização de diversos procedimentos como: biometria, marcação, transporte, exame físico, procedimentos cirúrgicos e manejo reprodutivo. Determinou-se a dose de benzocaína na anestesia de carpas (Cyprinus carpio, com a realização de seis etapas com 40 peixes cada. O peso médio das carpas em cada etapa foi de 147,45±7,99g, 173,32±9,15g, 191,26±14,05g, 269,84±19,24g, 285,25±17,97g, e 300,91±16,45g. Em cada etapa, os peixes foram capturados e colocados em quatro recipientes com benzocaína nas concentrações de 100, 140, 180 e 220 mg/L respectivamente. O tempo de indução (TI foi

  7. Interobserver and intraobserver reliability of two classification systems for intra-articular calcaneal fractures.

    Science.gov (United States)

    Lauder, Anthony J; Inda, David J; Bott, Aaron M; Clare, Michael P; Fitzgibbons, Timothy C; Mormino, Matthew A

    2006-04-01

    For a fracture classification to be useful it must provide prognostic significance, interobserver reliability, and intraobserver reproducibility. Most studies have found reliability and reproducibility to be poor for fracture classification schemes. The purpose of this study was to evaluate the interobserver and intraobserver reliability of the Sanders and Crosby-Fitzgibbons classification systems, two commonly used methods for classifying intra-articular calcaneal fractures. Twenty-five CT scans of intra-articular calcaneal fractures occurring at one trauma center were reviewed. The CT images were presented to eight observers (two orthopaedic surgery chief residents, two foot and ankle fellows, two fellowship-trained orthopaedic trauma surgeons, and two fellowship-trained foot and ankle surgeons) on two separate occasions 8 weeks apart. On each viewing, observers were asked to classify the fractures according to both the Sanders and Crosby-Fitzgibbons systems. Interobserver reliability and intraobserver reproducibility were assessed with computer-generated kappa statistics (SAS software; SAS Institute Inc., Cary, North Carolina). Total unanimity (eight of eight observers assigned the same fracture classification) was achieved only 24% (six of 25) of the time with the Sanders system and 36% (nine of 25) of the time with the Crosby-Fitzgibbons scheme. Interobserver reliability for the Sanders classification method reached a moderate (kappa = 0.48, 0.50) level of agreement, when the subclasses were included. The agreement level increased but remained in the moderate (kappa = 0.55, 0.55) range when the subclasses were excluded. Interobserver agreement reached a substantial (kappa = 0.63, 0.63) level with the Crosby-Fitzgibbons system. Intraobserver reproducibility was better for both schemes. The Sanders system with subclasses included reached moderate (kappa = 0.57) agreement, while ignoring the subclasses brought agreement into the substantial (kappa = 0.77) range

  8. Interlocking Nailing Versus Interlocking Plating in Intra-articular Calcaneal Fractures: A Biomechanical Study.

    Science.gov (United States)

    Reinhardt, Sophia; Martin, Heiner; Ulmar, Benjamin; Döbele, Stefan; Zwipp, Hans; Rammelt, Stefan; Richter, Martinus; Pompach, Martin; Mittlmeier, Thomas

    2016-08-01

    Open reduction and internal fixation with a plate is deemed to represent the gold standard of surgical treatment for displaced intra-articular calcaneal fractures. Standard plate fixation is usually placed through an extended lateral approach with high risk for wound complications. Minimally invasive techniques might avoid wound complications but provide limited construct stability. Therefore, 2 different types of locking nails were developed to allow for minimally invasive technique with sufficient stability. The aim of this study was to quantify primary stability of minimally invasive calcaneal interlocking nail systems in comparison to a variable-angle interlocking plate. After quantitative CT analysis, a standardized Sanders type IIB fracture model was created in 21 fresh-frozen cadavers. For osteosynthesis, 2 different interlocking nail systems (C-Nail; Medin, Nov. Město n. Moravě, Czech Republic; Calcanail; FH Orthopedics SAS; Heimsbrunn, France) as well as a polyaxial interlocking plate (Rimbus; Intercus GmbH; Rudolstadt, Germany) were used. Biomechanical testing consisted of a dynamic load sequence (preload 20 N, 1000 N up to 2500 N, stepwise increase of 100 N every 100 cycles, 0.5 mm/s) and a load to failure sequence (max. load 5000 N, 0.5 mm/s). Interfragmentary movement was detected via a 3-D optical measurement system. Boehler angle was measured after osteosynthesis and after failure occurred. No significant difference regarding load to failure, stiffness, Boehler angle, or interfragmentary motion was found between the different fixation systems. A significant difference was found with the dynamic failure testing sequence where 87.5% of the Calcanail implants failed in contrast to 14% of the C-Nail group (P plate. The highest load to failure was observed for the C-Nail. Boehler angle showed physiologic range with all implants before and after the biomechanical tests. Both minimally invasive interlocking nail systems displayed a high primary stability

  9. The significance of the intraarticular anesthesia of the tarsometatarsal joint for the diagnosis of lameness in the horse, with special reference to bone spavin

    International Nuclear Information System (INIS)

    Buchner, H.H.F.

    1991-01-01

    Intraarticular anesthesia of the tarsometatarsal joint as a part of the diagnosis of lameness in the horse was evaluated regarding the anatomical features and clinical importance. At first, in 37 hock joints of necropsy material the communications between tarsometatarsal and distal intertarsal joint were studied using simultaneously a corrosion casting technique and a radiographic contrast technique. Radiographically in 25.8 % of the cases a communication could be demonstrated. Using corrosion casting technique, in 9.1 % a wide connection between the joints was evident, whilst in 37.3 % only a low grade connection existed. In 40 hock joints of living horses, communication between the joints were evaluated arthrographically, using Conray 60 R as contrast medium. In 28 % of the tarsal joints communications between tarsometatarsal and distal intertarsal joint could be demonstrated. In 13 horses suffering from bone spavin the effect of the intraarticular tarsometatarsal anesthesia was evaluated: first in a subjective manner on judgement by the veterinarian, second in an objective manner using an optoelectronical locomotion analysis system (SELSPOT II). In 10 of these horses also the BERGE-anesthesia was evaluated. Using the locomotion analysis, a highly significant improvement of lameness was seen in 30 % of the horses following intraarticular tarsometatarsal anesthesia and in 28 % following BERGE-anesthesia. On subjective judgement after intraarticular tarsometatarsal anesthesia, 15.4% of the horses showed a moderate improvement, whilst 38.5% showed a middle graded improvement of the lameness. The necessity of a critical judgement of lameness after diagnostic anesthesias in cases of a minor degree hindlimb lameness has to be pointed out. There was no plain correlation between radiological findings and the results of intraarticular anesthesia. As a general tendency, horses with mild radiological changes do respond to intraarticular anesthesia better. Due to the lack of

  10. Atitudes atuais de anestesiologistas e médicos em especialização com relação à anestesia venosa total Actitudes actuales de anestesiólogos y médicos en especialización con relación a la anestesia venosa total Current attitude of anesthesiologists and anesthesiology residents regarding total intravenous anesthesia

    Directory of Open Access Journals (Sweden)

    Fernando Squeff Nora

    2006-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: No passado, tempo, custos, informações, treinamento e avaliação da profundidade da anestesia limitavam a aceitação da anestesia venosa total (TIVA. O objetivo deste estudo foi determinar atitudes de anestesiologistas e médicos em especialização com relação à anestesia venosa total. MÉTODO: Um questionário foi enviado a 150 anestesiologistas e 102 residentes. A concordância (C e discordância (D em cada item foram comparadas por testes z (consenso, se p JUSTIFICATIVA Y OBJETIVOS: Antiguamente, tiempo, costes, informaciones, capacitación y evaluación de la profundidad de la anestesia limitaban la aceptación de la anestesia venosa total (TIVA. El objetivo de este estudio fue el de determinar las actitudes de anestesiólogos y médicos en especialización con relación a la anestesia venosa total. MÉTODO: Un cuestionario fue enviado a 150 anestesiólogos y 102 residentes. La concordancia (C y discordancia (D en cada ítem se compararon por pruebas z (consenso, si p BACKGROUND AND OBJECTIVES: In the past, time, cost, information, training, and the evaluation of the plane of anesthesia limited the acceptance of total intravenous anesthesia (TIVA. The objective of this study was to determine the attitude of anesthesiologists and other anesthesiology residents regarding total intravenous anesthesia. METHODS: A questionnaire was sent to 150 anesthesiologists and 102 residents. The concordance (C and disaccord (D of each item were compared by z tests (consensus if p < 0.05. RESULTS: There were 98 responses. The data represent the number of answers for each category. The majority of the participants agreed that the quality of the awakening stimulates the use of the TIVA (C/D = 86/8; p < 0.05; that the future depends on the development of drugs with a fast onset of action and immediate recovery (C/D = 88/5; p < 0.05; that they would like to use TIVA more often (C/D = 72/21; p < 0.05; and to have more information

  11. O tempo e a anestesia obstétrica: da cosmologia caótica à cronobiologia El tiempo y la anestesia obstétrica: de la cosmología caótica a la cronobiología Time and obstetric anesthesia: from chaotic cosmology to chronobiology

    Directory of Open Access Journals (Sweden)

    Nilton Bezerra do Vale

    2009-10-01

    /morir, etc., y las condiciones ambientales (sincronizadores, influyen en la fisiología del parto en función de la existencia de relojes endógenos (osciladores, que interactúan con pistas sociales diuturnas. En esta revisión, fueron abordados los parámetros anestésico-obstétricos cíclicos más importantes en la atención a la parturiente. CONTENIDO: Análisis cronobiológico de los principales eventos de la fisiopatología obstétrica de la Mulier sapiens: I Período de la embriogénesis y riesgo de teratogénesis; II de la prematuridad al postdatismo: del parto eutócico al cerclaje uterino; III La noche y el parto: mayor incidencia nocturna del parto (facilitación fisiológica, y diurna de la cesárea (opción del obstetra; IV La luna y el parto (resultado no conclusivo; V guardia nocturna en la Anestesia Obstétrica: contingencia profesional de más riesgos; VI Tiempos de la cesárea: retirada fetal: tiempo UD (uterotomy - delivery, el más corto posible; corrección eficaz de la hipotensión arterial y valorización del tiempo de ayuno preanestésico; VII Variación circadiana de la distocia: dolor; contracción uterina; pérdida sanguínea; hipertensión arterial sistémica (HAS; riesgo de alergia y asma brónquica. En la fase nocturna, existe una mayor intensidad de contracción y más riesgos de hemorragia, de alergia y de asma. En contraposición, hay una falta de variación circadiana de la HAS en la eclampsia; VIII Cronofarmacología obstétrica: anestésicos locales, analgésicos, hipnóticos, anestésicos generales y bloqueadores neuromusculares. La cronergia explica el pico analgésico matinal de los opioides, el vespertino de los anestésicos locales y el nocturno de los anestésicos generales inhalatorios. CONCLUSIONES: El abordaje cronobiológico de la atención anestésica al parto en la maternidad, enfatiza la importancia obstétrica del ritmo circadiano en la humanización y seguridad del parto.BACKGROUND AND OBJECTIVES: Temporal cycles (dark

  12. Anestesia combinada e extubação precoce em paciente com persistência do canal arterial: relato de caso

    Directory of Open Access Journals (Sweden)

    Paulo Antônio de Mattos Gouvêa

    2001-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O canal arterial é uma estrutura que integra a circulação fetal. Fatores como prematuridade, hipóxia, acidose e sepse contribuem para a sua patência. O objetivo deste relato é demonstrar a utilização da anestesia combinada em cirurgia para correção da persistência do canal arterial. RELATO DO CASO: Paciente masculino, 14 meses, 11 kg,estado físico ASA II com infecções respiratórias de repetição, foi submetido à correção cirúrgica de PCA. Utilizou-se midazolam (0,5 mg.kg-1 por via oral, no pré-anestésico, seguido de indução inalatória com halotano 1-2%. A hidratação foi feita com solução de Ringer com lactato (8 ml.kg-1.h-1. Após intubação orotraqueal foi iniciada ventilação mecânica em sistema circular pediátrico com reabsorvedor de CO2. Procedeu-se bloqueio peridural torácico no espaço T1-T2 com injeção única de bupivacaína a 0,125% com adrenalina 1:800.000 no volume de 0,5 ml.kg-1. A manutenção foi feita com halotano (0,5-0,6 CAM. O procedimento cirúrgico durou 70 minutos e foi feito por toracotomia látero-posterior com boa estabilidade cardiovascular. A criança foi extubada na sala cirúrgica e encaminhada para SRPA em boas condições. CONCLUSÕES: A técnica de anestesia combinada em anestesia pediátrica promove melhora na qualidade da analgesia per e pós-operatória. O bloqueio peridural torácico, com indicação criteriosa, pode ser utilizado com bons resultados.

  13. Doença de Moyamoya e anestesia com sevoflurano fora do centro cirúrgico: relato de caso Enfermedad de Moyamoya y anestesia con sevoflurano fuera del centro quirúrgico: relato de caso Moyamoya disease and sevoflurane anesthesia outside the surgery center: case report

    OpenAIRE

    Sheila Braga Machado; Florentino Fernandes Mendes; Adriana de Campos Angelini

    2002-01-01

    JUSTIFICATIVA E OBJETIVOS: A doença de Moyamoya é uma desordem cerebrovascular progressiva que representa um desafio anestésico em virtude da precária circulação cerebral destes pacientes, constituindo-se numa importante causa de acidente vascular cerebral em indivíduos jovens. O objetivo deste relato é apresentar o caso de um paciente com doença de Moyamoya que foi submetido à anestesia geral com sevoflurano para procedimento diagnóstico fora do centro cirúrgico. RELATO DO CASO: Criança com ...

  14. Anestesia para paciente portadora de múltiplas afecções endócrinas: relato de caso Anestesia para paciente portadora de múltiples afecciones endocrinas: relato de caso Anesthesia in a patient with multiple endocrine abnormalities: case report

    OpenAIRE

    Renato Toledo Maciel; Fátima Carneiro Fernandes; Leonel dos Santos Pereira

    2008-01-01

    JUSTIFICATIVA E OBJETIVOS: O insulinoma é o tumor endócrino pancreático mais comum. Pode estar associado a neoplasias endócrinas múltiplas (NEM). Relatou-se o caso de paciente com distúrbios endócrinos múltiplos que, no entanto, não se enquadram em síndromes (NEM) já conhecidas e com particularidades clínico-anestésicas que influenciaram no manuseio de sua anestesia. RELATO DO CASO: Paciente feminina, 23 anos, apresentando hipoglicemias de difícil controle associadas à doença de Cushing e pro...

  15. Anestesia para septoplastia e turbinectomia em paciente portador de doença de von Willebrand: relato de caso Anestesia para septoplastia y turbinectomia en paciente portador de enfermedad de von Willebrand: relato de caso Anesthesia for septoplasty and turbinectomy in von Willebrand disease patient: case report

    OpenAIRE

    Múcio Paranhos de Abreu; André de Moraes Porto; Alexandre Leite Minari; Henrique Gonçalves Caseli

    2003-01-01

    JUSTIFICATIVA E OBJETIVOS: Embora a doença de von Willebrand seja o mais comum dos distúrbios hemorrágicos hereditários, as publicações nacionais, relacionando esta doença e a prática anestésica, são escassas. O objetivo deste relato é apresentar um caso de anestesia geral para septoplastia e turbinectomia em paciente portador de doença de von Willebrand - Tipo I, tratado profilaticamente com desmopressina (1-deamino-8-D-arginina vasopressina, DDAVP) nos períodos pré e pós-operatório. RELATO ...

  16. A randomized controlled trial of intra-articular triamcinolone and/or physiotherapy in shoulder capsulitis.

    Science.gov (United States)

    Ryans, I; Montgomery, A; Galway, R; Kernohan, W G; McKane, R

    2005-04-01

    To assess the effectiveness of intra-articular triamcinolone injection and physiotherapy singly or combined in the treatment of adhesive capsulitis of the shoulder. Eighty patients with adhesive capsulitis of less than 6 months duration were randomized to one of four groups: Group A, injection of triamcinolone 20 mg and eight sessions of standardized physiotherapy; Group B, injection of triamcinolone 20 mg alone; Group C, placebo injection and eight sessions of standardized physiotherapy; or Group D, placebo injection alone. All subjects were given an identical home exercise programme. Outcome measures were assessed at 6 weeks and 16 weeks. The primary outcome measure was Shoulder Disability Questionnaire (SDQ) score. Secondary outcomes were measurement of pain using a visual analogue scale (VAS), global disability using VAS and range of passive external rotation. A two-way analysis of variance was used to explore the effects of corticosteroid injection and physiotherapy. At 6 weeks, the SDQ had improved significantly more in the groups receiving corticosteroid injection (P = 0.004). Physiotherapy improved passive external rotation at 6 weeks (P = 0.02) and corticosteroid injection improved self-assessment of global disability at 6 weeks (P = 0.04). There was no interaction effect between injection and physiotherapy. At 16 weeks, all groups had improved to a similar degree with respect to all outcome measures. Corticosteroid injection is effective in improving shoulder-related disability, and physiotherapy is effective in improving the range of movement in external rotation 6 weeks after treatment.

  17. Intra-articular fractures of the distal tibia: Current concepts of management.

    Science.gov (United States)

    Sitnik, Alexandre; Beletsky, Aleksander; Schelkun, Steven

    2017-08-01

    Results of the treatment of intra-articular fractures of the distal tibia have improved significantly during the last two decades.Recognition of the role of soft tissues has led to the development of a staged treatment strategy. At the first stage, joint-bridging external fixation and fibular fixation are performed. This leads to partial reduction of the distal tibial fracture and allows time for the healing of soft tissues and detailed surgical planning.Definitive open reduction and internal fixation of the tibial fracture is performed at a second stage, when the condition of the soft tissues is safe. The preferred surgical approach(es) is chosen based on the fracture morphology as determined from standard radiographic views and computed tomography.Meticulous atraumatic soft-tissue handling and the use of modern fixation techniques for the metaphyseal component such as minimally invasive plate osteosynthesis further facilitate healing. Cite this article: EFORT Open Rev 2017;2:352-361. DOI: 10.1302/2058-5241.2.150047.

  18. Recurrent Hemarthroses After TKA Treated With an Intraarticular Injection of Yttrium-90.

    Science.gov (United States)

    Fine, Stephen; Klestov, Alex

    2016-03-01

    Recurrent hemarthroses after a TKA are uncommon and usually respond to nonoperative treatment or intervention using angiographic embolization or synovectomy. However, in rare circumstances, the problem can be resistant to treatment. We report the case of a patient who had recurrent hemarthroses after a TKA. During the first 18 months after surgery, the patient experienced 48 episodes consistent with bleeding into the knee. The bleeding episodes recurred despite use of traditional treatments, including arthroscopy, open synovectomy and embolization of a small, false aneurysm. The patient ultimately received an intraarticular injection of yttrium-90 silica/citrate, and the hemarthroses ceased soon after the injection. At last review, 25 months after the injection, the patient had experienced no additional bleeding episodes. On review of the literature, we found only one other report in which yttrium-90 was used successfully in a similar situation. Yttrium-90 may be considered a treatment option in patients with recurrent hemarthroses after TKA, especially when the condition has not responded to more traditional treatments. The long-term risk of treatment with yttrium-90 for recurrent hemarthroses after a TKA remains unclear.

  19. An outcomes assessment of intra-articular calcaneal fractures, using patient and physician's assessment profiles.

    LENUS (Irish Health Repository)

    Kennedy, J G

    2012-02-03

    Thirty-six patients with intra-articular displaced calcaneal fractures were examined to determine both physician- and patient-based outcomes. Three groups were selected. Group A was treated with open reduction and internal fixation, group B was treated with open reduction internal fixation and supplemental bone graft augmentation and the patients in group C were treated with plaster cast immobilisation and no formal operative treatment. All cohorts were well matched for age, sex and severity of injury. Patients were evaluated using both the American Foot and Ankle Society Scoring System (AFASS) and the short form 36 (SF-36). Minimum time to follow up was 4 years. No significant difference was observed between the three groups with regards to pain and functional outcomes using the AFASS score (P>0.05). No difference was observed between the three groups using the SF-36 score (P>0.1). A statistically significant difference was observed, using radiological criteria, between both groups A and B when compared to the non-operative group C. The rate of wound infection in groups A and B was 31.5%. No correlation was found between the SF-36 score and the AFASS score. No correlation was found between the radiological score and either the SF-36 or the AFASS score. This study has found that the conservative treatment of calcaneal fractures can produce satisfactory outcomes with lower morbidity than surgically treated fractures.

  20. TACTICS OF TREATMENT IN CHILDREN WITH INTRAARTICULAR FRACTURES OF THE DISTAL HUMERUS

    Directory of Open Access Journals (Sweden)

    Y. N. Proshchenko

    2012-01-01

    Full Text Available Material and methods. The authors studied 121 patients with intra-articular fractures of the distal humerus in age from 3 to 18 years. In the study group (consisted of 81 patients the displacement of the distal fragment retained after a single unsuccessful reduction. In these children open reduction and fixation were performed. In cases of damaged neurovascular bundle the authors carried out revision and reconstruction of damaged nerve and vascular trunks. The control group consisted of 40 children who were treated conservatively (closed reposition. Follow-up was at least 6 months after discharge. Results. Evaluation of the functional results showed improvement in 67,0% of patients in the study group and 33,0% - in the control group. In study group a good anatomic result was achieved in 73 (90% patients, satisfactory - in 6 (7,5% and poor - in 2 (2,5%. In the control group a good anatomical results were obtained in 7 (17,5% patients, satisfactory - in 14 (35%, poor -in 19 (47,5%. Conclusion. Indications for surgical treatment: secondary displacement of bone fragments after a single failure or closed reduction. Elimination of fragment displacement prevents posttraumatic contractures and deformities of the upper extremity, and contribute to the full restoration of elbow joint function.

  1. The effect of intra-articular levobupivacaine on shoulder cartilage at different doses-experimental study.

    Science.gov (United States)

    Özcan, Mustafa Soner; Kalem, Mahmut; Özçelik, Menekşe; Şahin, Ercan; Çakar, Sanem; Hayırlı, Nazlı; Evirgen, Oya; Ökten, Feyhan

    In this study it was aimed to examine the histological and morphometric effects on cartilage structure of intra-articular application of levobupivacaine to the shoulder joint. In twenty New Zealand adult male rabbits, 35 shoulders were used for the study and prepared in 5 groups of 7. These groups were defined as Groups L1, L2, L3 and L4 which were right shoulders administered with 0.25% and 0.5% levobupivacaine, Group C which were left shoulders as the control group and Groups S1 and S2 which were left shoulders administered with 0.9% saline. On the 2nd and 15th days the animals were killed, the glenohumeral joints were evaluated macroscopically then cartilage samples were taken. These samples were evaluated with Mankin score, and histomorphometrically by measuring the thickness of the cartilage between the superficial cartilage layer and the tidemark and the thickness of calcified cartilage between the tidemark and the subchondral bone. Macroscopically, on the 15th day the joint fluid was seen to have reduced in all the groups. After microscopic evaluation, the highest Mankin score (mean: 3.14±2.1/14) was in the L4 group (15th day 0.5% levobupivacaine) and was found to be statistically significant (pstudy. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.

  2. [The effect of intra-articular levobupivacaine on shoulder cartilage at different doses-experimental study].

    Science.gov (United States)

    Özcan, Mustafa Soner; Kalem, Mahmut; Özçelik, Menekşe; Şahin, Ercan; Çakar, Sanem; Hayırlı, Nazlı; Evirgen, Oya; Ökten, Feyhan

    In this study it was aimed to examine the histological and morphometric effects on cartilage structure of intra-articular application of levobupivacaine to the shoulder joint. In twenty New Zealand adult male rabbits, 35 shoulders were used for the study and prepared in 5 groups of 7. These groups were defined as Groups L1, L2, L3 and L4 which were right shoulders administered with 0.25% and 0.5% levobupivacaine, Group C which were left shoulders as the control group and Groups S1 and S2 which were left shoulders administered with 0.9% saline. On the 2nd and 15th days the animals were killed, the glenohumeral joints were evaluated macroscopically then cartilage samples were taken. These samples were evaluated with Mankin score, and histomorphometrically by measuring the thickness of the cartilage between the superficial cartilage layer and the tidemark and the thickness of calcified cartilage between the tidemark and the subchondral bone. Macroscopically, on the 15th day the joint fluid was seen to have reduced in all the groups. After microscopic evaluation, the highest Mankin score (mean: 3.14±2.1/14) was in the L4 group (15th day 0.5% levobupivacaine) and was found to be statistically significant (pstudy. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  3. Prospective Evaluation of Intra-Articular Dextrose Prolotherapy for Treatment of Osteoarthritis in Dogs.

    Science.gov (United States)

    Sherwood, J Matthew; Roush, James K; Armbrust, Laura J; Renberg, Walter C

    The objective of this study was to evaluate intra-articular dextrose prolotherapy for osteoarthritis of the elbow or stifle in dogs in a randomized, double-blind, placebo-controlled, prospective pilot study. Seventeen dogs were evaluated with 10 meeting inclusion criteria for this study. Evaluations included orthopedic exam, visual lameness scoring, Canine Brief Pain Inventory (CBPI), goniometry, kinetic gait analysis, and radiography. Initial lameness score, age, body weight, duration of lameness, and CBPI scores did not differ between groups. Change in CBPI pain severity score in the prolotherapy group from wk 6-12 was significantly less improved than in the placebo group, with no other significant differences in pain severity or pain interference scores between groups. Range of motion and radiographic scores did not differ between groups at any time. Mean kinetic forces improved in prolotherapy dogs but were not significantly different between treatment groups at any time. Although easily performed and well-tolerated, there were no statistically significant benefits of dextrose prolotherapy for treatment of osteoarthritis of the elbow and stifle in dogs. Post hoc power analysis of these sample means and standard deviations found that 29-106 animals per group would be necessary to demonstrate significant differences in kinetic forces, providing useful guidance for future studies.

  4. Single intra-articular injection of high molecular weight hyaluronic acid for hip osteoarthritis.

    Science.gov (United States)

    Rivera, Fabrizio

    2016-03-01

    Intra-articular (IA) injection of hyaluronic acid (HA) into the hip joint appears to be safe and well tolerated but only a small number of randomized clinical trials in humans has been published. The objective of this prospective study was to evaluate the efficacy and safety of a single IA injection of high-molecular-weight (2800 kDa) HA (Coxarthrum) for hip osteoarthritis. All patients received a single IA administration of 2.5 % sodium hyaluronate (75 mg/3 mL) of high molecular weight. Fluoroscopy requires an iodized contrast medium (iopamidol, 1 ml) which highlights the capsule before administering HA. Patients were evaluated before IA injection (T0), after 3 months, after 6 months and after 1 year from injection. Results were evaluated by the Brief Pain Inventory (BPI II), Harris Hip Score and a visual analog scale of pain (pain VAS). All treated patients were considered for statistical analysis. Two hundred seven patients were included at T0. The mean age was 67 years (range 46-81). Regarding BPI severity score, changes in pain between T0 and the three following visits were statistically highly significant (p injection of Coxarthrum is effective from the third month and that the results are stable or continue to improve up to 1 year. IV.

  5. Need for Bone Grafts in the Surgical Treatment of Displaced Intra-Articular Calcaneal Fractures.

    Science.gov (United States)

    Duymus, Tahir Mutlu; Mutlu, Serhat; Mutlu, Harun; Ozel, Omer; Guler, Olcay; Mahirogullari, Mahir

    Controversy is ongoing regarding the use of bone grafts to fill cavities that occur with collapse of the posterior facet in the joint and for repair of the calcaneal height with plating. The present study included 40 patients with 43 displaced intra-articular calcaneal fractures treated with open reduction and internal fixation from March 2009 to November 2013. In the present case-control study, the patients were separated into 2 groups: group A received an allograft (20 patients, 22 calcaneal fractures) and group B did not (20 patients, 21 calcaneal fractures). The calcaneal height and Böhler's angle were compared between the 2 groups. The final outcomes for all patients were evaluated using the American Orthopaedic Foot and Ankle Society (AOFAS) ankle hindfoot scale score and compared between the 2 groups. No significant differences were observed between the groups with regard to the basic demographic variables (p > .05). Using Sanders classification, 8 (18%) were type 2, 19 (44%) were type 3, and 16 (37%) were type 4 fractures. The comparisons between the 2 groups showed a loss of Böhler's angle and loss of calcaneal height that was significantly greater in group B (p  .05). In conclusion, although no differences were found in the clinical results between the 2 groups, more satisfactory radiologic results were obtained in group A, in which bone grafts were used. Copyright © 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

  6. Posterior facet cartilage injury in operatively treated intra-articular calcaneus fractures.

    Science.gov (United States)

    Rothberg, David L; Yoo, Brad J

    2014-10-01

    Direct visualization of the posterior facet in displaced intra-articular calcaneus fractures (DIACF) frequently shows partial or full thickness cartilage delamination. This is felt to be secondary to the depression of an osteoarticular segment of the posterior facet within the calcaneal body and the subsequent contact with fracture edges as it impacts caudally. The purpose of this study was to determine the frequency of cartilage injury and if it correlates with fracture classification. A single surgeon prospective, observational series of 28 patients with 28 DIACFs was reviewed for patient demographic and injury data, radiographic fracture characterization, and intraoperative observation of articular injury size, depth, and location over the time period of February 2010 to December 2012. Observations were correlated with the OTA and Sanders classification systems. Age, sex, mechanism of injury, and depth and location of cartilage injury were not significantly different between the 13 OTA/Sanders type 2 and 15 type 3 DIACFs evaluated in this study. Posterior facet articular cartilage delamination was found in 77% of type 2 and 100% of type 3 fractures (P = .09). Location of cartilage injury was common (56%) along the distal, lateral aspect of the posterior facet (P fractures (3.1%) then type 2 (1.3%) (P fractures compared to type 2 fractures. Level IV, prospective, observational series. © The Author(s) 2014.

  7. Arthroscopic approach and intraarticular anatomy of the stifle in South American camelids.

    Science.gov (United States)

    Pentecost, Rebecca L; Niehaus, Andrew J; Santschi, Elizabeth

    2012-05-01

    To describe a cranial arthroscopic approach to the stifle of South American camelids and to report our clinical experience with camelid stifle arthroscopy. Experimental study and retrospective case series. (1) Cadaveric alpaca hindlimbs (n = 18; 9 alpacas); (2) 1 alpaca and 1 llama Polymethylmethacrylate joint casts (n = 2) were made to define stifle joint dimensions. Cadaveric stifle joints (n = 16) were evaluated arthroscopically to determine arthroscopic portal locations, describe the intraarticular anatomy, and report potential complications. An alpaca and a llama with stifle joint disease had diagnostic arthroscopy. Successful entry into the stifle joint was achieved in 16 cadaver limbs. Observed structures were: the suprapatellar pouch, articular surface of the patella, femoral trochlear ridges and groove, cranial aspect of the femoral condyles (n = 16); distal aspect of the cranial and proximal aspect of the caudal cruciate ligaments (14); and cranial aspects of the medial and lateral menisci (11), and cranial meniscotibial and intermeniscal ligaments (8). Stifle arthroscopy allowed for joint evaluation and removal of osteochondral fragments in 1 alpaca and 1 llama with naturally occurring stifle disease. Complications of cadaver or live procedures included minor cartilage scoring (3 stifles) and subcutaneous periarticular fluid accumulation (8 stifles). Arthroscopy provides a safe approach for diagnosis and treatment of stifle lesions in South American camelids. Copyright 2012 by The American College of Veterinary Surgeons.

  8. Methods and Variables Associated with the Risk of Septic Arthritis Following Intra-Articular Injections in Horses: A Survey of Veterinarians.

    Science.gov (United States)

    Gillespie, Caroline C; Adams, Stephen B; Moore, George E

    2016-11-01

    To determine common methods for intra-articular injections and variables associated with the risk of septic arthritis following intra-articular injection in the horse. Cross-sectional survey. Equine veterinarians. A link to an online survey was distributed to equine practitioners in 2014. Responses for descriptive data were tabulated. Data on infection rates obtained from medical records were analyzed. Variables associated with the risk of septic arthritis were determined using χ 2 or Fisher's exact tests and logistic regression. Common current methods for intra-articular injections were determined from 241 surveys. Sixty-four of 241 surveys (26.6%) contained data with numbers of joints injected and number of infections obtained from review of medical records. Eight different injection methods were used by more than 2/3 of responding veterinarians. A total of 67 out of 319,760 injected joints reported became septic following injection, giving an incidence of 2.10 septic joints per 10,000 intra-articular injections. Based on multivariate analysis, infection rates were significantly lower when veterinarians prepared their own injection sites (OR=0.10) and had septic arthritis following intra-articular injection and a large number of injection methods reported by responding veterinarians. The low reported incidence of infection may be related to the large number of practitioners frequently using common methods. © Copyright 2016 by The American College of Veterinary Surgeons.

  9. Fluoroscopy-guided intrA-articular facet joint steroid injection for the management of low back pain: Therapeutic effectiveness and arthrographic pattern

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Su Jin; Lee, Jun Woo; Lee, Guen Young; You, Ja Yeon; Kang, Heung Sik [Dept. of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam (Korea, Republic of); Chai, Jae Won [Dept. of Radiology, SMG-SNU Boramae Medical Center, Seoul (Korea, Republic of); Ahn, Joong Mo [Dept. of Radiology, University of Pittsburgh Medical Center, Pittsburgh (United States)

    2015-09-15

    To evaluate the effectiveness of fluoroscopy-guided intra-articular facet joint steroid injection for the management of low back pain, and to document the incidence of epidural leakage. In total, 320 facet joint injections of 244 consecutive patients were included in this study. All patients had undergone an intra-articular facet joint steroid injection in 2007 and had follow-up post-treatment medical records. The response to treatment was analyzed on the basis of chart documentation (aggravated, no change, slightly improved, much improved, no pain). Fluoroscopic arthrograms of the injections were retrospectively analyzed by two radiologists. Of the 244 patients, 85.2% (n = 208) showed improvement after an initial intra-articular facet joint steroid injection. A total of 77.9% (n = 162) of the patients showed symptom recurrence, with a median of a 69 day symptom-free interval, while 30.3% (n = 74) of the patients showed symptom-free intervals of more than six months. Overall, 74 (33.3%) of the 222 cases of intra-articular facet joint steroid injections without concomitant epidural steroid injection showed epidural leakage in fluoroscopic arthrograms. Fluoroscopy-guided intra-articular facet joint injection is a reliable technique for the management of low back pain, with excellent immediate effectiveness and good prolonged (> 2 months) pain relief. Epidural leakage during injection was detected in one-third of the cases.

  10. Exploring reasons for the observed inconsistent trial reports on intra-articular injections with hyaluronic acid in the treatment of osteoarthritis: Meta-regression analyses of randomized trials.

    Science.gov (United States)

    Johansen, Mette; Bahrt, Henriette; Altman, Roy D; Bartels, Else M; Juhl, Carsten B; Bliddal, Henning; Lund, Hans; Christensen, Robin

    2016-08-01

    The aim was to identify factors explaining inconsistent observations concerning the efficacy of intra-articular hyaluronic acid compared to intra-articular sham/control, or non-intervention control, in patients with symptomatic osteoarthritis, based on randomized clinical trials (RCTs). A systematic review and meta-regression analyses of available randomized trials were conducted. The outcome, pain, was assessed according to a pre-specified hierarchy of potentially available outcomes. Hedges׳s standardized mean difference [SMD (95% CI)] served as effect size. REstricted Maximum Likelihood (REML) mixed-effects models were used to combine study results, and heterogeneity was calculated and interpreted as Tau-squared and I-squared, respectively. Overall, 99 studies (14,804 patients) met the inclusion criteria: Of these, only 71 studies (72%), including 85 comparisons (11,216 patients), had adequate data available for inclusion in the primary meta-analysis. Overall, compared with placebo, intra-articular hyaluronic acid reduced pain with an effect size of -0.39 [-0.47 to -0.31; P hyaluronic acid. Based on available trial data, intra-articular hyaluronic acid showed a better effect than intra-articular saline on pain reduction in osteoarthritis. Publication bias and the risk of selective outcome reporting suggest only small clinical effect compared to saline. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Anestesia para el tratamiento intraparto extraútero (EXIT) en fetos con diagnóstico prenatal de malformaciones cervical y oral: relato de casos

    OpenAIRE

    Helfer, Daniel Corrêa [UNIFESP; Clivatti, Jefferson [UNIFESP; Yamashita, Américo Massafuni [UNIFESP; Moron, Antonio Fernandes [UNIFESP

    2012-01-01

    JUSTIFICATIVA E OBJETIVOS: O feto com diagnóstico pré-natal de massa cervical, ou qualquer outra doença que obstrua as vias aéreas, não deve ser abordado de forma convencional por apresentar dois desafios ao médico assistente logo após o parto: o tempo limitado para se estabelecer o acesso a vias aéreas potencialmente difíceis e a ausência de anestesia do neonato caso seja necessária instrumentação das vias aéreas. O procedimento EXIT (ex utero intrapartum treatment - EXIT procedure) consiste...

  12. Anestesia epidural com associação medetomidina e lidocaína, em gatos pré-medicados com acepromazina e midazolam

    Directory of Open Access Journals (Sweden)

    D.A.S.D. Lima

    2011-04-01

    Full Text Available Avaliaram-se os efeitos anestésicos promovidos pela associação medetomidina e lidocaína por via epidural, em gatos pré-tratados com acepromazina e midazolam. Foram utilizados 10 gatos adultos, machos e fêmeas, hígidos e com média de peso de 2,5±0,6kg, distribuídos em dois grupos (GM e GL de igual número (n=5. Administraram-se, como medicação pré-anestésica, acepromazina, 0,2mg/kg, e midazolam, 0,5mg/kg, via intramuscular, e 20 minutos depois, nos animais do GM, por via epidural, lidocaína, 4,4mg/kg, associada à medetomidina, 0,02mg/kg. Os gatos do GL receberam lidocaína, 4,4mg/kg, associada à solução de NaCl a 0,9%. As avaliações ocorreram antes da pré-anestesia (MPA, 20 minutos após a MPA e antes da anestesia epidural, e aos 10, 20, 30 e 40 minutos após a anestesia epidural, respectivamente, T-20, T0, T10, T20, T30 e T40. Foram avaliados: frequência cardíaca (FC e respiratória (FR, temperatura do corpo, saturação de oxiemoglobina, analgesia, miorrelaxamento e período de recuperação. No GM, a FC diminuiu em T20, T30 e T40 em relação ao T-20 e T10 e foi mais baixa que a FC do GL em T20, T30 e T40, respectivamente, 86, 91 e 88 bat/min e 194, 205 e 177 bat/min. A FR variou entre o T-20 e os outros momentos de avaliação nos animais do GL. Nas variáveis eletrocardiográficas, houve diferenças entre T20, T30 e T40 e T-20 e T0, valores de 235, 238 e 240ms e 156 e 161ms, respectivamente, somente no GM. Este grupo diferiu do GL nas avaliações em T20, T30 e T40, valores de 147, 132 e 150ms para os gatos do GL. Oitenta por cento dos gatos tiveram analgesia intensa, e em todos os animais ocorreu relaxamento da mandíbula e da língua. O tempo de recuperação foi de 40 e 15min no GM e no GL, respectivamente. Concluiu-se que a associação lidocaína com medetomidina promoveu plano anestésico estável com grau de anestesia e recuperação anestésica de boa qualidade.

  13. Modelo de anestesia em coelhos para procedimentos no tórax Anesthesia model in rabbits for thoracic surgery

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    Elias Kallas

    2001-06-01

    Full Text Available A intubação endotraqueal em coelhos é dificil. O risco anestésico não é desprezível pela estreita margem de segurança entre o plano anestésico e o óbito. Tais fatos despertaram nosso interesse por uma solução simples e segura. Dez animais machos receberam por via intramuscular acepromazina, cetamina e xilazina. Após dez minutos procedeu-se exposição do ligamentum cricothyroideum , o qual foi incisado para colocação de tubo endotraqueal iniciando-se a administração de oxigênio e halotano. A punção arterial foi realizada para controle da pressão arterial média. Procedeu-se toracotomia no quinto espaço intercostal esquerdo com biópsia do pulmão e colabamento pulmonar, iniciando-se a ventilação seletiva do pulmão contra-lateral. Amostras sangüíneas, para medida do pH, foram colhidas no início do procedimento, após o colabamento pulmonar e no final, antes da expansão do pulmão, 30 minutos após o colabamento. Fechado o tórax, foi retirado o tubo endotraqueal tão logo o animal apresentasse recuperação dos reflexos e a seguir suturado ligamentum cricothyroideum. Os animais foram submetidos a eutanásia 14 dias após, quando procedeu-se a nova biópsia pulmonar, a retirada da traquéia e da laringe, para exame. Concluiu-se que este é um procedimento simples e seguro de anestesia para cirurgia torácica em coelhos.The endotracheal intubation of rabbits is difficult. The anesthetic risk is high because of the narrow difference between the effective and the lethal dose. We used a safe and simple method. Ten male animals received intramuscular injection of acepromazine, cetamine, and xylazine. Ten minutes later, an endotracheal canula was inserted trough a small cervical incision on the crico-tyroid membrane, to administrate oxigen and halothane. Thoracotomy was performed in the 5th. left intercostal space and a pulmonary biopsy too. The left lung collapsed and ventilation of the right lung remained for the next 30

  14. Quimioterapia e anestesia

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    Márcio Augusto Lacerda

    2001-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A quimioterapia é um dos principais tipos de tratamento oferecido a pacientes com câncer, mas ainda causam importantes efeitos colaterais, reversíveis ou não. Para os anestesiologistas, conhecer estas drogas, complicações e interações medicamentosas, é de importância capital em cirurgias com pacientes em tratamento de neoplasias. CONTEÚDO: Nesta revisão apresentam-se os diferentes tipos de quimioterápicos atualmente utilizados, a classificação farmacológica, repercussões orgânicas, interações com outras substâncias, e a conduta anestésica mais apropriada frente a elas, objetivando reduzir a morbi-mortalidade perioperatória nestes pacientes. CONCLUSÕES: O conhecimento, pelo anestesiologista, das formas de tratamento, das características farmacológicas destas substâncias, seus efeitos adversos, lesões estruturais e possíveis interações medicamentosas por elas geradas e potencializadas pelas várias técnicas anestésicas hoje empregadas, pode certamente reduzir a morbi-mortalidade peri-operatória destes pacientes.

  15. Efectos de la toxina botulínica A (Botox®) intraarticular en la artrosis de rodilla avanzada Effects of intraarticular Botulinum Toxin A (Botox®) on refractory knee osteoarthritis

    OpenAIRE

    P. Fenollosa Vázquez; R. M. Izquierdo Aguirre; M. A. Canós Verdecho; J. Pallarés Delgado

    2011-01-01

    Objetivos: la osteoartritis es la enfermedad articular más común y una de los problemas de salud más frecuentes y sintomáticos en la madurez y senectud. Este trabajo describe nuestra experiencia clínica con inyecciones intraarticulares de toxina botulínica tipo A (TBA) en dolor de rodilla artrósico y refractario. Materiales y métodos: doce mujeres con gonartrosis avanzada y refractaria, acudieron a consulta para el manejo del dolor de rodilla de moderado a severo. Las pacientes estuvieron en ...

  16. Doença de Moyamoya e anestesia com sevoflurano fora do centro cirúrgico: relato de caso Enfermedad de Moyamoya y anestesia con sevoflurano fuera del centro quirúrgico: relato de caso Moyamoya disease and sevoflurane anesthesia outside the surgery center: case report

    Directory of Open Access Journals (Sweden)

    Sheila Braga Machado

    2002-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A doença de Moyamoya é uma desordem cerebrovascular progressiva que representa um desafio anestésico em virtude da precária circulação cerebral destes pacientes, constituindo-se numa importante causa de acidente vascular cerebral em indivíduos jovens. O objetivo deste relato é apresentar o caso de um paciente com doença de Moyamoya que foi submetido à anestesia geral com sevoflurano para procedimento diagnóstico fora do centro cirúrgico. RELATO DO CASO: Criança com 13 anos, estado físico ASA IV, portadora de doença de Moyamoya com seqüela neurológica após três acidentes vasculares cerebrais, insuficiência renal crônica e hipertensão arterial sistêmica, submetida à endoscopia digestiva alta. Em decúbito dorsal e após monitorização, realizou-se indução inalatória pela cânula de traqueostomia com sevoflurano (aumento gradual da concentração inspiratória até 6% e mistura de oxigênio/óxido nitroso a 50%. Um cateter venoso foi inserido para infusão de solução glicosada a 5%. Foi realizada ventilação controlada manual, sendo a manutenção da anestesia feita com sevoflurano a 4% e mistura de oxigênio/óxido nitroso a 50%. Ao final do procedimento os agentes anestésicos foram descontinuados simultaneamente e foi administrado oxigênio a 100%. A anestesia foi satisfatória, com boa estabilidade hemodinâmica, sem ocorrência de complicações durante o procedimento e com despertar precoce. CONCLUSÕES: O sevoflurano pode oferecer novas perspectivas para a anestesia inalatória em pacientes com doença neurológica que realizam procedimento ambulatorial, já que permite boa estabilidade hemodinâmica e despertar precoce, preservando a fisiologia cerebral.JUSTIFICATIVA Y OBJETIVOS: La enfermedad de Moyamoya es un desorden cerebrovascular progresivo que representa un desafío anestésico en virtud de la precaria circulación cerebral de estos pacientes, constituyéndose una importante

  17. Anestesia para separação de gêmeos isquiópagos no período neonatal: relato de caso Anestesia para separación de gemelos isquiópagos en el período neonatal Anesthetic management for neonatal conjoined twins separation: case report

    Directory of Open Access Journals (Sweden)

    Norma Sueli Pinheiro Módolo

    2002-07-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A separação de gêmeos unidos causa grande interesse devido à complexidade da anestesia e cirurgia, à raridade da patologia e às poucas chances de sobrevida. O objetivo desta descrição é o de contribuir para a literatura existente, relatando os desafios encontrados por nossa equipe no atendimento à cirurgia-anestesia de separação de gêmeos isquiópagos. RELATO DO CASO: Pacientes gêmeos, nascidos a termo, de parto cesariano, pesando juntos 5.100 g, classificados como isquiópagus tetrapus. Duas equipes anestésico-cirúrgicas estavam presentes, sendo o procedimento anestésico esquematizado com aparelho de anestesia, cardioscópio, capnógrafo, oxímetro de pulso, termômetro elétrico, estetoscópio esofágico, todos em dobro. Realizou-se indução anestésica com halotano e fentanil, com os gêmeos em posição lateral e com rotação da cabeça em 45º para facilitar a intubação traqueal. Os recém-nascidos foram mantidos em ventilação controlada manualmente, utilizando o sistema de Rees-Baraka. A anestesia foi mantida com halotano, oxigênio e fentanil. Durante o per-operatório, foram encontrados órgãos abdominais duplos, com exceção do cólon, que era único. As bexigas e os ísquios estavam ligados. Ao final da cirurgia as duas crianças apresentavam-se com sinais vitais estáveis. Os gêmeos permaneceram na Unidade de Terapia Intensiva (UTI Neonatal por quatro semanas e receberam alta em bom estado geral. CONCLUSÕES: Ressalta-se a importância do entrosamento da equipe, do estudo retrospectivo multidisciplinar, da monitorização adequada e acurada observação clínica; todos esses fatores contribuíram para a boa evolução e alta dos gêmeos.JUSTIFICATIVA Y OBJETIVOS: La separación de gemelos unidos causa gran interés debido a la complexidad de la anestesia y cirugía, a la raridad de la patología y a las pocas chances de sobrevida. El objetivo de esta descripción es el de contribuir

  18. A Case Report of Intra-articular Bee Venom Pharmacopuncture combining with oriental medical treatment for Acute Traumatic Partial Tear of Meniscus.

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    Lee Jae-Hoon

    2010-12-01

    Full Text Available This case was report of intra-articular bee venom pharmacopuncture injection on the patient with Acute Traumatic Partial tear of meniscus. We used intra-articular bee venom pharmacopuncture injection to Acute Traumatic Partial tear of meniscus diagnosed by symptoms and MR imaging. Be under treatment if necessary we prescribed herbal medication and physiotherapy. The state of patient was measured by Visual Analog Scale(VAS and Walking time and Western Ontario and McMaster Universities(WOMAC Index score. After several times of treatments, noticeable reduction of pain was measured and increased time of walking on floor and decreased WOMAC score. This results suggest that intra-articular bee venom pharmacopuncture injection are effective to treatments of Acute Traumatic Partial tear of meniscus.

  19. Intra-articular hyaluronan is without clinical effect in knee osteoarthritis: a multicentre, randomised, placebo-controlled, double-blind study of 337 patients followed for 1 year

    DEFF Research Database (Denmark)

    Jørgensen, Anette; Stengaard-Pedersen, Kristian; Simonsen, Ole

    2010-01-01

    OBJECTIVE: To examine the long-term efficacy and safety of five intra-articular injections with hyaluronan in knee osteoarthritis. METHODS: A multicentre, randomised, placebo-controlled double-blind study of 337 patients fulfilling the American College of Rheumatology (ACR) criteria for knee...... osteoarthritis (clinical and laboratory) and with a Lequesne algofunctional index score (LFI) of 10 or greater. Patients received a hyaluronan product (sodium hyaluronate; Hyalgan) (n=167) or saline (n=170) intra-articularly weekly for 5 weeks and were followed up to 1 year. Time to recurrence was the primary...... the ACR criteria for osteoarthritis of the knee with moderate to severe disease activity (LFI > or = 10), five intra-articular injections of hyaluronan did not improve pain, function, paracetamol consumption or other efficacy parameters 3, 6, 9 and 12 months after the treatment....

  20. Appropriateness of clinical and organizational criteria for intra-articular injection therapies in osteoarthritis: A Delphi method consensus initiative among experts in Italy

    Directory of Open Access Journals (Sweden)

    Marco Paoloni

    2015-06-01

    Full Text Available OBJECTIVE: The aim of the study was to identify the main aspects involved in patient selection, the choice of therapeutic agents and the safety profile, as well as the medico-legal and organizational aspects of intra-articular injection therapies for osteoarthritis. METHODS: A committee of 10 experts from Italian universities, public hospitals, territorial services, research institutes and patient associations was set up. Fifty-two clinicians from a large number of Italian medical centers specialized in intra-articular injection therapy took part in a Delphi process aimed at obtaining consensus statements among the participants. RESULTS: Large consensus was obtained for statements grouped under the following main themes: treatment indications; drug/medical device choice; treatment efficacy; and appropriate setting. CONCLUSIONS: The consensus statements developed by a large number of experts may be used as a practical reference tool to help physicians treat osteoarthritis patients by means of intra-articular injection therapies.

  1. Combination of Intra-Articular and Intraosseous Injections of Platelet Rich Plasma for Severe Knee Osteoarthritis: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Mikel Sánchez

    2016-01-01

    Full Text Available The aim of this study was to assess a novel approach to treating severe knee osteoarthritis by targeting synovial membrane, superficial articular cartilage, synovial fluid, and subchondral bone by combining intra-articular injections and intraosseous infiltrations of platelet rich plasma. We explored a new strategy consisting of intraosseous infiltrations of platelet rich plasma into the subchondral bone in combination with the conventional intra-articular injection in order to tackle several knee joint tissues simultaneously. We assessed the clinical outcomes through osteoarthritis outcome score (KOOS and the inflammatory response by quantifying mesenchymal stem cells in synovial fluid. There was a significant pain reduction in the KOOS from baseline (61.55±14.11 to week 24 (74.60±19.19, after treatment (p=0.008, in the secondary outcomes (symptoms, p=0.004; ADL, p=0.022; sport/rec., p=0.017; QOL, p=0.012, as well as VAS score (p<0.001 and Lequesne Index (p=0.008. The presence of mesenchymal stem cells in synovial fluid and colony-forming cells one week after treatment decreased substantially from 7.98±8.21 MSC/μL to 4.04±5.36 MSC/μL (p=0.019 and from 601.75±312.30 to 139.19±123.61  (p=0.012, respectively. Intra-articular injections combined with intraosseous infiltrations of platelet rich plasma reduce pain and mesenchymal stem cells in synovial fluid, besides significantly improving knee joint function in patients with severe knee osteoarthritis. This trial is registered on EudraCT with the number 2013-003982-32.

  2. Comparison of the effectivity of oral and intra-articular administration of tenoxicam in patients with knee osteoarthritis.

    Science.gov (United States)

    Erbas, Mesut; Simsek, Tuncer; Kiraz, Hasan Ali; Sahin, Hasan; Toman, Huseyin

    2015-01-01

    Tenoxicam is widely used in osteoarthritis treatment and we aimed to compare the effectivity of oral and intra-articular administration of tenoxicam in osteoarthritis treatment. This study was performed between 2011 and 2012 by retrospectively analyzing and comparing the findings of 60 patients who were clinically and radiologically diagnosed with knee degenerative osteoarthritis in Bünyan state hospital pain policlinic. 60 patients included in the study were divided into two groups. The first group (tenoxicam IA, n=30) included patient findings of those subjected to intra-articular injection of 20mg tenoxicam to the knee once a week for three weeks and the second group (oral tenoxicam, n=30) included patients who were administered 20mg oral tenoxicam once a day for three weeks. All patients were clinically evaluated pre-treatment and in the 1st week, 1st month and 3rd month post-treatment according to specified criteria. Twenty two of 60 patients included in the study were male and 38 were female. In both groups significant improvements were detected in all of the observed parameters: visual analog scale, Western Ontario McMaster Osteoarthritis Index (pain, physical activity, knee stiffness) and Lequesne index scores and in the evaluations performed in 1st week, 1st month and 3rd month with respect to pre-treatment values. Besides, a better compliance to treatment and gastrointestinal system tolerability in tenoxicam IA group was also observed. Intra-articular tenoxicam administration could be thought as an alternative treatment method in patients with knee osteoarthritis who cannot use oral tenoxicam especially due to systemic gastrointestinal system side effects and those who have difficulties in adapting to treatment. Copyright © 2014 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.

  3. [Comparison of the effectivity of oral and intra-articular administration of tenoxicam in patients with knee osteoarthritis].

    Science.gov (United States)

    Erbas, Mesut; Simsek, Tuncer; Kiraz, Hasan Ali; Sahin, Hasan; Toman, Huseyin

    2015-01-01

    Tenoxicam is widely used in osteoarthritis treatment and we aimed to compare the effectivity of oral and intra-articular administration of tenoxicam in osteoarthritis treatment. This study was performed between 2011 and 2012 by retrospectively analyzing and comparing the findings of 60 patients who were clinically and radiologically diagnosed with knee degenerative osteoarthritis in Bünyan state hospital pain policlinic. 60 patients included in the study were divided into two groups. The first group (tenoxicam IA, n=30) included patient findings of those subjected to intra-articular injection of 20mg tenoxicam to the knee once a week for three weeks and the second group (oral tenoxicam, n=30) included patients who were administered 20mg oral tenoxicam once a day for three weeks. All patients were clinically evaluated pre-treatment and in the 1st week, 1st month and 3rd month post-treatment according to specified criteria. 22 of 60 patients included in the study were male and 38 were female. In both groups significant improvements were detected in all of the observed parameters: visual analog scale, Western Ontario McMaster Osteoarthritis Index (pain, physical activity, knee stiffness) and Lequesne index scores and in the evaluations performed in 1st week, 1st month and 3rd month with respect to pre-treatment values. Besides, a better compliance to treatment and gastrointestinal system tolerability in tenoxicam IA group was also observed. Intra-articular tenoxicam administration could be thought as an alternative treatment method in patients with knee osteoarthritis who cannot use oral tenoxicam especially due to systemic gastrointestinal system side effects and those who have difficulties in adapting to treatment. Copyright © 2014 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  4. Operative versus non-operative treatment for closed, displaced, intra-articular fractures of the calcaneus: randomised controlled trial.

    Science.gov (United States)

    Griffin, Damian; Parsons, Nick; Shaw, Ewart; Kulikov, Yuri; Hutchinson, Charles; Thorogood, Margaret; Lamb, Sarah E

    2014-07-24

    To investigate whether surgery by open reduction and internal fixation provides benefit compared with non-operative treatment for displaced, intra-articular calcaneal fractures. Pragmatic, multicentre, two arm, parallel group, assessor blinded randomised controlled trial (UK Heel Fracture Trial). 22 tertiary referral hospitals, United Kingdom. 151 patients with acute displaced intra-articular calcaneal fractures randomly allocated to operative (n=73) or non-operative (n=78) treatment. The primary outcome measure was patient reported Kerr-Atkins score for pain and function (scale 0-100, 100 being the best possible score) at two years after injury. Secondary outcomes were complications; hindfoot pain and function (American Orthopaedic Foot and Ankle Society score); general health (SF-36); quality of life (EQ-5D); clinical examination; walking speed; and gait symmetry. Analysis was by intention to treat. 95% follow-up was achieved for the primary outcome (69 in operative group and 74 in non-operative group), and a complete set of secondary outcomes were available for 75% of participants. There was no significant difference in the primary outcome (mean Kerr-Atkins score 69.8 in operative group v 65.7 in non-operative group; adjusted 95% confidence interval of difference -7.1 to 7.0) or in any of the secondary outcomes between treatment groups. Complications and reoperations were more common in those who received operative care (estimated odds ratio 7.5, 95% confidence interval 2.0 to 41.8). Operative treatment compared with non-operative care showed no symptomatic or functional advantage after two years in patients with typical displaced intra-articular fractures of the calcaneus, and the risk of complications was higher after surgery. Based on these findings, operative treatment by open reduction and internal fixation is not recommended for these fractures.Trial registration Current Controlled Trials ISRCTN37188541. © Griffin et al 2014.

  5. Treatment of athletes with symptomatic intra-articular hip pathology and athletic pubalgia/sports hernia: a case series.

    Science.gov (United States)

    Larson, Christopher M; Pierce, Bradley R; Giveans, M Russell

    2011-06-01

    The purpose of the study was to evaluate the results of surgical treatment in athletes with associated intra-articular hip pathology and extra-articular sports pubalgia. Between December 2003 and September 2009, 37 hips (mean patient age, 25 years) were diagnosed with both symptomatic athletic pubalgia and symptomatic intra-articular hip joint pathology. There were 8 professional athletes, 15 collegiate athletes, 5 elite high school athletes, and 9 competitive club athletes. Outcomes included an evaluation regarding return to sports and modified Harris Hip Score, Short Form 12 score, and visual analog scale score. We evaluated 37 hips at a mean of 29 months (range, 12 to 78 months) after the index surgery. Thirty-one hips underwent thirty-five athletic pubalgia surgeries. Hip arthroscopy was performed in 32 hips (30 cases of femoroacetabular impingement treatment, 1 traumatic labral tear, and 1 borderline dysplasia). Of 16 hips that had athletic pubalgia surgery as the index procedure, 4 (25%) returned to sports without limitations, and 11 (69%) subsequently had hip arthroscopy at a mean of 20 months after pubalgia surgery. Of 8 hips managed initially with hip arthroscopy alone, 4 (50%) returned to sports without limitations, and 3 (43%) had subsequent pubalgia surgery at a mean of 6 months after hip arthroscopy. Thirteen hips had athletic pubalgia surgery and hip arthroscopy at one setting. Concurrent or eventual surgical treatment of both disorders led to improved postoperative outcomes scores (P pubalgia or intra-articular hip pathology in this patient population, outcomes were suboptimal. Surgical management of both disorders concurrently or in a staged manner led to improved postoperative outcomes scoring and an unrestricted return to sporting activity in 89% of hips. Level IV, therapeutic case series. Copyright © 2011 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  6. Is intra-articular pathology associated with MCL edema on MR imaging of the non-traumatic knee?

    Energy Technology Data Exchange (ETDEWEB)

    Blankenbaker, Donna G.; De Smet, Arthur A. [University of Wisconsin Medical School, Division of Musculoskeletal Imaging, Department of Radiology, Madison (United States); Fine, Jason P. [University of Wisconsin, Department of Statistics, Madison (United States); University of Wisconsin, Department of Biostatistics and Informatics, Madison (United States)

    2005-08-01

    Edema surrounding the medial collateral ligament (MCL) is seen on MR imaging in patients with MCL injuries and in patients with radiographic osteoarthritis in the non-traumatic knee. Because we noted MCL edema in patients without prior trauma or osteoarthritis, we studied the association between intra-articular pathology and MCL edema in patients without knee trauma. We evaluated the MR examinations of 247 consecutive patients (121 male, 126 female with a mean age of 44 years) without recent trauma for the presence of edema surrounding the MCL, meniscal and ACL tears, medial meniscal extrusion, medial compartment chondromalacia, and osteoarthritis. The percentages of patients illustrating MCL edema with and without each type of pathology were compared using Fisher's exact test to determine if there was a statistically significant association. We found MCL edema in 60% of 247 patients. MCL edema was present in 67% of patients with medial meniscal tears, 35% with lateral meniscal tears, 100% with meniscal extrusion of 3 mm or more, 78% with femoral chondromalacia, 82% with tibial chondromalacia, and 50% with osteoarthritis. The percentage of patients with edema increased with the severity of the chondromalacia. These associations were all statistically significant (p <0.02). The mean age of those with MCL edema was 49.7 years compared with 34.9 years without MCL edema (p <0.001). Patient gender and ACL tear did not correlate with MCL edema. Nine (4%) of the 247 patients had MCL edema without intra-articular pathology. None of these 9 patients had MCL tenderness or joint laxity on physical examination. We confirmed that MCL edema is associated with osteoarthritis, but is also associated with meniscal tears, meniscal extrusion, and chondromalacia. In addition, MCL edema can be seen in patients without intra-articular pathology, recent trauma or MCL abnormality on physical examination. (orig.)

  7. Disposition of isoflupredone acetate in plasma, urine and synovial fluid following intra-articular administration to exercised Thoroughbred horses.

    Science.gov (United States)

    Knych, Heather K; Harrison, Linda M; White, Alexandria; McKemie, Daniel S

    2016-01-01

    The use of isoflupredone acetate in performance horses and the scarcity of published pharmacokinetic data necessitate further study. The objective of the current study was to describe the plasma pharmacokinetics of isoflupredone acetate as well as time-related urine and synovial fluid concentrations following intra-articular administration to horses. Twelve racing-fit adult Thoroughbred horses received a single intra-articular administration (8 mg) of isoflupredone acetate into the right antebrachiocarpal joint. Blood, urine and synovial fluid samples were collected prior to and at various times up to 28 days post drug administration. All samples were analyzed using liquid chromatography-Mass Spectrometry. Plasma data were analyzed using a population pharmacokinetic compartmental model. Maximum measured plasma isoflupredone concentrations were 1.76 ± 0.526 ng/mL at 4.0 ± 1.31 h and 1.63 ± 0.243 ng/mL at 4.75 ± 0.5 h, respectively, for horses that had synovial fluid collected and for those that did not. The plasma beta half-life was 24.2 h. Isoflupredone concentrations were below the limit of detection in all horses by 48 h and 7 days in plasma and urine, respectively. Isoflupredone was detected in the right antebrachiocarpal and middle carpal joints for 8.38 ± 5.21 and 2.38 ± 0.52 days, respectively. Results of this study provide information that can be used to regulate the use of intra-articular isoflupredone in the horse. Copyright © 2015 John Wiley & Sons, Ltd.

  8. Disposition of methylprednisolone acetate in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.

    Science.gov (United States)

    Knych, H K; Harrison, L M; Casbeer, H C; McKemie, D S

    2014-04-01

    Methylprednisolone acetate (MPA) is commonly administered to performance horses, and therefore, establishing appropriate withdrawal times prior to performance is critical. The objectives of this study were to describe the plasma pharmacokinetics of MPA and time-related urine and synovial fluid concentrations following intra-articular administration to sixteen racing fit adult Thoroughbred horses. Horses received a single intra-articular administration of MPA (100 mg). Blood, urine, and synovial fluid samples were collected prior to and at various times up to 77 days postdrug administration and analyzed using tandem liquid chromatography-mass spectrometry (LC-MS/MS). Maximum measured plasma MPA concentrations were 6.06 ± 1.57 at 0.271 days (6.5 h; range: 5.0-7.92 h) and 6.27 ± 1.29 ng/mL at 0.276 days (6.6 h; range: 4.03-12.0 h) for horses that had synovial fluid collected (group 1) and those that did not (group 2), respectively. The plasma terminal half-life was 1.33 ± 0.80 and 0.843 ± 0.414 days for groups 1 and 2, respectively. MPA was undetectable by day 6.25 ± 2.12 (group 1) and 4.81 ± 2.56 (group 2) in plasma and day 17 (group 1) and 14 (group 2) in urine. MPA concentrations in synovial fluid remained above the limit of detection (LOD) for up to 77 days following intra-articular administration, suggesting that plasma and urine concentrations are not a good indicator of synovial fluid concentrations. © 2013 John Wiley & Sons Ltd.

  9. Ultrasound-guided intra-articular and rotator interval corticosteroid injections in adhesive capsulitis of the shoulder: a double-blind, sham-controlled randomized study.

    Science.gov (United States)

    Prestgaard, Tore; Wormgoor, Marjon E A; Haugen, Simen; Harstad, Herlof; Mowinckel, Petter; Brox, Jens Ivar

    2015-09-01

    Adhesive capsulitis (frozen shoulder) is a common cause of shoulder pain and disability. Previous studies have reported that intra-articular corticosteroid injections are of benefit compared with placebo up to 6 weeks. It has been suggested that the structures primarily involved in adhesive capsulitis are the capsule and the rotator interval. Systematic reviews have concluded that there is limited evidence of the treatment effectiveness of intra-articular corticosteroid injections and that high-quality primary research is required. The aim of this study was to compare ultrasound-guided intra-articular corticosteroid injection and combined intra-articular and rotator interval injection in a double-blind, sham-controlled randomized clinical trial. The main outcome measure was the group difference in change in shoulder pain (0-10) at 6 weeks. One hundred twenty-two patients were randomized (42 to intra-articular injection, 40 to combined intra-articular/interval injection, and 40 to sham injection). For both corticosteroid injection groups, there was a significant difference compared with sham injection at week 6. The mean group difference (adjusted for gender, age, dominant arm, and duration) in change in shoulder pain for the intra-articular vs sham injection was -1.7 (95% confidence interval, -2.7 to -0.6, P = 0.002) and -2.1 (95% confidence interval, -3.2 to -1.1, P = 0.0001) for the combined injection vs sham injection. The significant group differences were maintained at week 12 but not at week 26. Similar results were found for the secondary outcome measures (night pain, Shoulder Pain and Disability Index). Differences between the corticosteroid groups were not significant at any time.

  10. [Treatment of the complex intraarticular fracture of the distal humerus with the latitude elbow prosthesis].

    Science.gov (United States)

    Burkhart, Klaus Josef; Müller, Lars Peter; Schwarz, Christina; Mattyasovszky, Stefan Georg; Rommens, Pol Maria

    2010-07-01

    Therapy of comminuted intraarticular distal humerus fractures in elderly patients with primary total elbow arthroplasty to achieve stable and painless function. Use of "third-generation" elbow prosthesis with the following options:--linked total elbow arthroplasty,--unlinked total elbow arthroplasty,--either with or without radial head replacement,--hemiarthroplasty. Comminuted intraarticular distal humerus fractures with poor bone quality, in which stable osteosynthesis is impossible. Failure of internal fixation without the technical possibility of revision osteosynthesis. Posttraumatic osteoarthritis or rheumatoid arthritis. Open fractures (Gustilo-Anderson type II or III) or contaminated wounds should not initially be treated with total elbow arthroplasty. Prosthetic replacement may be considered after consolidation of the soft tissue. Low compliance, high functional demands. Paralysis of the biceps muscle. Supine positioning of the patient. Surgical approach after Bryan-Morrey. Anterior transposition of the ulnar nerve. Preparation of the insertion of the triceps at the distal humerus, capsule and proximal ulna. Reflection of the triceps in continuity with the ulnar periosteum and the forearm fascia. Attempt at reconstruction of the epicondyles to achieve ligamentary stability and to implant an unlinked prosthesis. If this is technically not possible, the prosthesis is linked at the end of the operation. Removal of the distal humerus fragments. Determination of the prosthesis size. Detection of the extension-flexion axis. Opening of the humeral intramedullary canal. Determination of the offset. Preparation of the humeral prosthesis repository. Placement of the trial prosthesis. Potential implantation of a hemiprosthesis, if radial head, proximal ulna and ligaments are unaffected. Otherwise preparation of the ulnar prosthesis repository. If the radial head is unaffected, it can be preserved. Otherwise it has to be resected and preferably replaced. Placement of

  11. Intra-articular injection in patients with juvenile idiopathic arthritis: factors associated with a good response.

    Science.gov (United States)

    Cunha, Ana Luiza Garcia; Miotto E Silva, Vanessa Bugni; Osaku, Fabiane Mitie; Niemxeski, Luísa Brasil; Furtado, Rita Nely Vilar; Natour, Jamil; Sande, Maria Teresa de; Terreri, Lemos Ramos Ascensão

    Intra-articular injection of corticosteroids (IIC) for treatment of patients with juvenile idiopathic arthritis (JIA) is increasingly used in Pediatric Rheumatology. To describe the clinical course of patients undergoing IIC in our Pediatric Rheumatology Unit. Retrospective study of patients with JIA undergoing IIC from January 2008 to December 2012, with a minimum follow-up of six months after the injection. Good response to IIC was set as the presence of inactivity on the infiltrated joint by at least six months. Eighty-eight patients underwent a total of 165 IICs. Of these, 75% were girls and 35.2% had persistent oligoarticular JIA. The mean age at diagnosis was 6.8 years, and when IIC was carried out, 12.2 years. Regarding patients, younger age at diagnosis (p=0.037) and the occurrence of uveitis in the course of the disease (p=0.015) were associated with good response to IIC. From 165 IICs, 63% had a good response and joints remained inactive for a median of 18.1 months. The type of joint injection (p=0.001), lesser values stated in the overall visual analog scale by the physician (p=0.015) and by parents/patient (p=0.01) have been associated with a good response to IIC. Nine adverse events (5.4%) were observed. In our study, more than half of the joints showed a good response to IIC. Younger patients at diagnosis and uveitis during the course of the disease had good response to IIC. Knees, wrists and elbows were the joints that best responded to IIC. IIC proved to be a safe procedure. Copyright © 2016 Elsevier Editora Ltda. All rights reserved.

  12. Intraarticular injections (corticosteroid, hyaluronic acid, platelet rich plasma) for the knee osteoarthritis

    Science.gov (United States)

    Ayhan, Egemen; Kesmezacar, Hayrettin; Akgun, Isik

    2014-01-01

    Osteoarthritis (OA) is a complex “whole joint” disease pursued by inflammatory mediators, rather than purely a process of “wear and tear”. Besides cartilage degradation, synovitis, subchondral bone remodeling, degeneration of ligaments and menisci, and hypertrophy of the joint capsule take parts in the pathogenesis. Pain is the hallmark symptom of OA, but the extent to which structural pathology in OA contributes to the pain experience is still not well known. For the knee OA, intraarticular (IA) injection (corticosteroids, viscosupplements, blood-derived products) is preferred as the last nonoperative modality, if the other conservative treatment modalities are ineffective. IA corticosteroid injections provide short term reduction in OA pain and can be considered as an adjunct to core treatment for the relief of moderate to severe pain in people with OA. IA hyaluronic acid (HA) injections might have efficacy and might provide pain reduction in mild OA of knee up to 24 wk. But for HA injections, the cost-effectiveness is an important concern that patients must be informed about the efficacy of these preparations. Although more high-quality evidence is needed, recent studies indicate that IA platelet rich plasma injections are promising for relieving pain, improving knee function and quality of life, especially in younger patients, and in mild OA cases. The current literature and our experience indicate that IA injections are safe and have positive effects for patient satisfaction. But, there is no data that any of the IA injections will cause osteophytes to regress or cartilage and meniscus to regenerate in patients with substantial and irreversible bone and cartilage damage. PMID:25035839

  13. Functional outcome of intra-articular tibial plateau fractures: the impact of posterior column fractures.

    Science.gov (United States)

    van den Berg, Juriaan; Reul, Maike; Nunes Cardozo, Menno; Starovoyt, Anastasiya; Geusens, Eric; Nijs, Stefaan; Hoekstra, Harm

    2017-09-01

    INTRODUCTION: Although regularly ignored, there is growing evidence that posterior tibial plateau fractures affect the functional outcome. The goal of this study was to assess the incidence of posterior column fractures and its impact on functional outcome and general health status. We aimed to identify all clinical variables that influence the outcome and improve insights in the treatment strategies. A retrospective cohort study including 218 intra-articular tibial plateau fractures was conducted. All fractures were reclassified and applied treatment was assessed according to the updated three-column concept. Relevant demographic and clinical variables were studied. The patient reported outcome was assessed using the Knee injury and Osteoarthritis Outcome Score (KOOS). Median follow-up was 45.5 (IQR 24.9-66.2) months. Significant outcome differences between operatively and non-operatively treated patients were found for all KOOS subscales. The incidence of posterior column fractures was 61.9%. Posterior column fractures, sagittal malalignment and an increased complication rate were associated with poor outcome. Patients treated according to the updated three-column concept, showed significantly better outcome scores than those patients who were not. We could not demonstrate the advantage of posterior column fracture fixation, due to a limited patient size. Our data indicates that implementation of the updated three-column classification concept may improve the surgical outcome of tibial plateau fractures. Failure to recognize posterior column fractures may lead to inappropriate utilization of treatment techniques. The current concept allows us to further substantiate the importance of reduction and fixation of posterior column fractures with restoration of the sagittal alignment. 3.

  14. Prognostic value of computed tomography classification systems for intra-articular calcaneus fractures.

    Science.gov (United States)

    Swords, Michael P; Alton, Timothy B; Holt, Sarah; Sangeorzan, Bruce J; Shank, John R; Benirschke, Stephen K

    2014-10-01

    There are several published computed tomography (CT) classification systems for calcaneus fractures, each validated by a different standard. The goal of this study was to measure which system would best predict clinical outcomes as measured by a widely used and validated musculoskeletal health status questionnaire. Forty-nine patients with isolated intra-articular joint depression calcaneus fractures more than 2 years after treatment were identified. All had preoperative CT studies and were treated with open reduction and plate fixation using a lateral extensile approach. Four different blinded reviewers classified injuries according to the CT classification systems of Crosby and Fitzgibbons, Eastwood, and Sanders. Functional outcomes evaluated with a Musculoskeletal Functional Assessment (MFA). The mean follow-up was 4.3 years. The mean MFA score was 15.7 (SD = 11.6), which is not significantly different from published values for midfoot injuries, hindfoot injuries, or both, 1 year after injury (mean = 22.1, SD = 18.4). The classification systems of Crosby and Fitzgibbons, Eastwood, and Sanders, the number of fragments of the posterior facet, and payer status were not significantly associated with outcome as determined by the MFA. The Sanders classification trended toward significance. Anterior process comminution and surgeon's overall impression of severity were significantly associated with functional outcome. The amount of anterior process comminution was an important determinant of functional outcome with increasing anterior process comminution significantly associated with worsened functional outcome (P = .04). In addition, the surgeon's overall impression of severity of injury was predictive of functional outcome (P = .02), as determined by MFA. Level III, comparative series. © The Author(s) 2014.

  15. In vitro evaluation and intra-articular administration of biodegradable microspheres containing naproxen sodium.

    Science.gov (United States)

    Bozdağ, S; Caliş, S; Kaş, H S; Ercan, M T; Peksoy, I; Hincal, A A

    2001-01-01

    The dispersion of non-steroidal antiinflammatory drugs (NSAIDs) into biodegradable polymeric matrices have been accepted as a good approach for obtaining a therapeutic effect in a predetermined period of time meanwhile minimizing the side effects of NSAIDs. In the present study, it was aimed to prepare Naproxen Sodium (NS), (a NSAID) loaded microsphere formulation using natural Bovine Serum Albumin (BSA) and synthetic biodegradable polymers such as poly(lactide-co-glycolic acid) (PLGA) (50:50 MW 34,000 and 88,000 Da) for intra-articular administration, and to study the retention of the drug at the site of injection in the knee joint. NS incorporated microspheres were evaluated in vitro for particle size (the mean particle size; for BSA microspheres, 10.0 +/- 0.3 microm, for PLGA microspheres, 9.0 +/- 0.2 and 5.0 +/- 0.1 microm for MW 34,000 and 88,000 Da, respectively), yield value, drug loading, surface morphology and drug release. For in vivo studies, monoarticular arthritis was induced in the left knee joints of rabbits by using ovalbumin and Freund's Complete Adjuvant as antigen and adjuvant. A certain time (4 days) is allowed for the formation of arthritis in the knee joints, then the NS loaded microspheres were injected directly into the articular cavity. At specific time points, gamma scintigrams were obtained to determine the residence time of the microspheres in knee joints, in order to determine the most suitable formulation. This study indicated that PLGA, a synthetic polymer, is more promising than the natural type BSA microspheres for an effective cure of mono-articular arthritis in rabbits.

  16. Efeito da anestesia geral na cognição e na memória do idoso Efecto de la anestesia general en la cognición y memoria del paciente de edad avanzada Effects of general anesthesia in elderly patients’ memory and cognition

    Directory of Open Access Journals (Sweden)

    Régis Borges Aquino

    2004-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A anestesia geral e a função mental têm sido alvo de estudos e considerações, especialmente pelo sentimento de que ela, particularmente em idosos, poderia induzir alterações na cognição e na memória. O objetivo dessa pesquisa foi avaliar o efeito da anestesia geral na cognição e na memória do idoso correlacionando-a ao sexo, à idade e ao tempo de anestesia. MÉTODO: Estudo de coorte controlado realizado em pacientes categorizados em dois grupos de observação: a- anestésico; b- clínicos (controle. As variáveis de desfecho consideradas foram os escores dos testes MiniMental, de Fluência Verbal e de Lembrança Numérica. Anestesia geral com halotano, isoflurano, sevoflurano, tiopental, propofol, etomidato, fentanil alfentanil, succinilcolina atracúrio, pancurônio. Intra-operatório com PaCO2 entre 30 e 45 mmHg e saturação de hemoglobina acima de 90% e tolerância de PA com diminuição até 20% do valor basal. Foram excluídos os pacientes que apresentaram algum evento adverso no intra e pós-operatório. Dados categóricos analisados pelo teste do Qui-quadrado. A comparação inicial entre os grupos no momento basal (pré-anestésico foi realizada pelo t de Student para amostras independentes. Para avaliação do efeito do processo anestésico ao longo do tempo, foi utilizada a Análise de Variância (ANOVA para medidas repetidas. RESULTADOS: No teste do MiniMental os grupos apresentaram comportamento semelhante sendo notado aumento de escores ao longo do tempo. No teste de Fluência Verbal, em ambos os grupos os escores mantiveram-se praticamente inalterados. No teste de Lembrança Numérica o comportamento dos grupos foi muito semelhante ao longo do seguimento sendo que os escores aumentaram em ambos os grupos. CONCLUSÕES: Não foi detectado declínio de cognição ou de memória no pós-operatório de idosos de 60 a 80 anos de ambos os sexos, submetidos à anestesia geral com duração de 3 a

  17. A Rare Intra-articular Pathology of Knee Lipoma Arborescens: A Report of Two Cases Managed by Arthroscopic Synovectomy

    Directory of Open Access Journals (Sweden)

    Sung Yee Lee

    2014-12-01

    Full Text Available Lipoma arborescens is a rare intra-articular condition of unknown exact aetiology. Lipoma arborescens is one of the differential diagnoses of diffuse chronic swelling of the knee and its magnetic resonance imaging (MRI appearance is diagnostic. We present two cases of patients with recurrent knee effusion. MRI showed a frond-like fatty synovial mass and joint effusion that suggested the likelihood of lipoma arborescens. Arthroscopic synovectomy was performed and pathology confirmed the diagnosis. There was no recurrence of symptoms after synovectomy.

  18. Clinical benefit of intra-articular saline as a comparator in clinical trials of knee osteoarthritis treatments

    DEFF Research Database (Denmark)

    Altman, Roy D; Devji, Tahira; Bhandari, Mohit

    2016-01-01

    OBJECTIVES: Hyaluronic acid and corticosteroids are common intra-articular (IA) therapies widely used for the management of mild to moderate knee osteoarthritis (OA). Many trials evaluating the efficacy of IA administered therapies commonly use IA saline injections as a placebo comparator arm...... in the meta-analysis. Based on data with moderate inconsistency IA saline was found to significantly improve short-term knee pain in 32 studies involving 1705 patients (SMD = -0.68; 95% CI: -0.78 to -0.57; P injection...... with saline in 19 studies involving 1445 patients (SMD = -0.61; 95% CI: -0.76 to -0.45; P injection with saline...

  19. Intra-articular distribution pattern after ultrasound-guided injections in wrist joints of patients with rheumatoid arthritis

    DEFF Research Database (Denmark)

    Boesen, Mikael; Jensen, Karl Erik; Torp-Pedersen, Søren

    2007-01-01

    OBJECTIVE: To investigate the distribution of an ultrasound-guided intra-articular (IA) injection in the wrist joint of patients with rheumatoid arthritis (RA). METHODS: An ultrasound-guided IA drug injection into the wrist joint was performed in 17 patients with 1 ml methylprednisolone (40 mg....../ml), 0.5 ml Lidocaine (5mg/ml) and 0.15 ml gadolinium (Omniscan 0.5 mmol/ml). The drug solution was placed in the central proximal part of the wrist between the distal radius and the lunate bone. Coronal and axial MRI sequences were performed after the injection to visualize the distribution. Carpal...

  20. A new building block: costo-osteochondral graft for intra-articular incongruity after distal radius fracture.

    Science.gov (United States)

    Tang, Chris Yuk Kwan; Fung, Boris; Poon, T L; Fok, Margaret

    2014-01-01

    Even with the invention of locking plates, intra-articular fractures of distal radius with extreme comminution remain a challenge for orthopaedic surgeons. Osteochondral graft is a potential choice to reconstruct the articular defect. We report a patient who had a fracture of distal radius with costo-osteochondral graft for articular reconstruction which has not yet been described in the English literature. At nine-year follow-up, he was pain free and had full range of movement of the wrist. The authors suggest that costo-osteochondral graft could be an option with satisfactory result.

  1. Uso de plasma rico em plaquetas intra-articulares como tratamento pós-cirúrgico da ruptura do ligamento cruzado cranial num cão

    Directory of Open Access Journals (Sweden)

    R.F. Silva

    2012-08-01

    Full Text Available Relata-se o caso de um cão que recebeu injeções intra-articulares de plasma rico em plaquetas (PRP durante o pós-operatório do tratamento cirúrgico de ruptura do ligamento cruzado cranial (RLCCr. Os resultados clínicos e da avaliação da marcha mediante plataforma de força neste paciente sugerem a utilização de injeções intra-articulares de PRP como terapia pós-cirúrgica no tratamento da RLCCr.

  2. Perfil y grado de la hiperglucemia tras la infiltración de corticoesteroides intra-articular en pacientes con y sin diabetes tipo 2

    OpenAIRE

    Moya Alvarado, Patricia

    2011-01-01

    Las infiltraciones intra-articulares de concorticoesteroides suelen indicarse como tratamiento coadyuvante en casos de presencia de dolor y limitación de la movilidad. La información existente sobre los efectos en el metabolismo hidrocarbonado son muy escasos y dispares. El objetivo de este estudio es definir el patrón y grado de la hiperglucemia después de la administración intra-articular de acetónido de triamcinolona en pacientes sin diabetes y con diabetes tipo 2. Se realiza un estudio ob...

  3. Anestesia neuroaxial comparada à anestesia geral para revascularização dos membros inferiores em idosos: revisão sistemática com metanálise de ensaios clínicos aleatórios Anestesia neuroaxial comparada a la anestesia general para la revascularización de los miembros inferiores en ancianos: revisión sistemática con metanálisis de ensayos clínicos aleatorios Neuroaxis block compared to general anesthesia for revascularization of the lower limbs in the elderly: a systematic review with metanalysis of randomized clinical studies

    Directory of Open Access Journals (Sweden)

    Fabiano Timbó Barbosa

    2009-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A controvérsia atual é saber se a anestesia neuroaxial (AN é mais eficiente que a geral (AG em idosos submetidos à cirurgia não-cardíaca. O objetivo foi determinar a eficiência da AN comparada à AG para revascularização de membros inferiores (RMI em idosos. MÉTODO: Utilizada estratégia de busca para as bases de dados: MEDLINE (1955 a 2007, CINHAL ( 1982 a 2007, Embase (1980 a 2007, LILACS (1982 a 2007 e ISI (1945 a 2007. Dois revisores analisaram independentemente os artigos em busca de ensaios clínicos aleatórios (ECA que comparassem a AN com a AG para a RMI. O texto completo dos ECA que atendessem aos critérios de inclusão foram analisados. Discordâncias foram analisadas em reuniões de consenso. A metanálise foi realizada com o software Review Manager, por meio da razão de chances com intervalo de confiança de 95%. RESULTADOS: Foram selecionados três artigos originais envolvendo 465 pacientes. Não houve significância estatística na metanálise das variáveis: mortalidade (OR: 0,90; IC 95%: 0,30 - 2,73; P = 0,85 raquianestesia; OR: 1,30; IC 95%: 0,38 - 4,48; P = 0,68 anestesia peridural, infarto miocárdico (OR: 1,38; IC 95%: 0,29 - 6,46; P = 0,68 e taxa de amputação dos membros inferiores (OR: 0,81; IC 95%: 0,30 - 2,19; P = 0,68 raquianestesia; OR: 0,70; IC 95%: 0,24 - 2,07; P = 0,52 anestesia peridural. Houve significância estatística para pneumonia (OR: 0,37; IC 95%: 0,15 - 0,89; P = 0,03, porém houve heterogeneidade clínica. CONCLUSÕES: As evidências geradas nessa metanálise foram insuficientes para demonstrar que a AN é mais eficiente, equivalente, ou menos eficiente quando comparada a AG para RMI em idosos.JUSTIFICATIVA Y OBJETIVOS: La controversia actual es saber si la anestesia neuroaxial (AN es más eficaz que la anestesia general (AG en ancianos sometidos a la cirugía no cardíaca. El objetivo fue determinar la eficacia de la AN comparada con la AG para revascularizaci

  4. Safety and tolerability of intra-articular hyaluronic acid (Sinovial®/GELSYN-3tm) injections in the treatment of knee osteoarthritis.

    Science.gov (United States)

    Abate, M; Salini, V

    2017-01-01

    Osteoarthritis (OA) is a progressively degenerative joint disease, with a very high prevalence rate that is expected to increase worldwide with the ageing of the population. Considering that OA requires long-term treatment, therapies with minimal side effects and which can be repeated as needed are warranted. Hyaluronic acid (HA), a natural glycosaminoglycan with viscoelastic properties, is a major component of synovial fluid and the extracellular matrix of the joint cartilage, and plays key roles in maintaining synovial fluid viscosity and the bio-mechanical integrity of healthy cartilage. Intra-articular administration of exogenous HA has therefore been used to successfully improve the viscoelastic properties of the joint to improve lubrication, modulate inflammation and modify the catabolic micro-environment. Sinovial®/GELSYN-3TM is a sterile, non-pyrogenic formulation of highly purified, chemically unmodified HA of bio-fermentative origin, which has been introduced in several different concentrations in clinical use within the European market. This expert opinion reports on the published data regarding the efficacy and tolerability of first and multiple injection series of Sinovial®-based product formulations. The data regarding the tolerability of Sinovial® in patients with knee osteoarthritis were analyzed, showing that this formulation, beside favourable therapeutic effects, has a very good tolerability profile, with only mild, transient, and easily managed, local injection-site reactions and absence of systemic reactions. In particular, repetitive cycles of HA have been shown to yield positive results in terms of both efficacy and safety and therefore should be offered to patients who had undergone a successful first course of therapy when their symptoms reoccur.

  5. Ropivacaína, articaína ou combinação de ropivacaína e articaína em anestesia peridural para cesariana: estudo randomizado, prospectivo e duplo-cego Ropivacaína, articaína o la combinación de ropivacaína y articaína en la anestesia epidural para cesárea: estudio aleatorio, prospectivo y doble ciego Ropivacaine, articaine or combination of ropivacaine and articaine for epidural anesthesia in cesarean section: a randomized, prospective, double-blinded study

    Directory of Open Access Journals (Sweden)

    Derya Arslan Yurtlu

    2013-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Iniciar a anestesia peridural com anestésicos locais de longa duração consome uma quantidade significativa de tempo, o que pode ser problemático em centros de anestesia obstétrica muito movimentados. Aventamos a hipótese de que uma combinação de articaína e ropivacaína proporcionaria início mais rápido e mesmo uma recuperação precoce das características do bloqueio sensório-motor. MÉTODOS: Sessenta parturientes a termo agendadas para cesariana eletiva foram randomicamente alocadas em três grupos para receber 20 mL de articaína a 2% (Grupo A, 10 mL de articaína a 2% + 10 mL de ropivacaína a 0,75% (Grupo AR ou 20 mL de ropivacaína a 0,75% (Grupo R via cateter peridural. O tempo de início do bloqueio sensorial até T10-T6 e o nível máximo de bloqueio, o tempo para a regressão de dois segmentos do nível máximo de bloqueio sensorial e o tempo de início e duração do bloqueio motor foram todos registrados. A necessidade de analgésicos adicionais, intra- e pós-operatoriamente, também foi registrada. RESULTADOS: Os dados demográficos foram semelhantes. Os tempos de início do bloqueio sensorial até os níveis T10 e T6 foram significativamente menores nos grupos A e AR, em comparação com o Grupo R (p JUSTIFICATIVA Y OBJETIVOS: Iniciar la anestesia epidural con anestésicos locales de larga duración consume una cantidad significativa de tiempo, siendo un problema en los centros de anestesia obstétrica que tienen mucho movimiento. Barajamos la hipótesis de que una combinación de articaína y ropivacaína proporcionaría un inicio más rápido e incluso una rápida recuperación de las características del bloqueo sensitivo motor. MÉTODOS: Sesenta parturientes a término que tenían cita para la cesárea electiva se ubicaron aleatoriamente en tres grupos para recibir 20 mL de articaína al 2% (Grupo A, 10 mL de articaína al 2% + 10 mL de ropivacaína al 0,75% (Grupo AR o 20 mL de ropivaca

  6. Anestesia local y Sedación para Intubación con Fibrobroncoscopio de paciente con Vía Aérea Difícil

    OpenAIRE

    García Rueda, Antonio; Mané Ruíz, N; Miyagi Yonamine, M; Herrera Merino, N; González Pérez, L

    2011-01-01

    Presentamos el caso clínico de un varón de 60 años con vía aérea difícil que debía realizarse una tiroidectomía total por el diagnóstico de bocio multinodular tóxico y que, un mes antes, había tenido un intento fallido de intubación con fibrobroncoscopio.

  7. Estudo de lidocaína a 0,5% e combinação de lidocaína a 0,25% com fentanil e vecurônio em anestesia regional intravenosa para cirurgias de membros superiores

    Directory of Open Access Journals (Sweden)

    Santhosh MCB

    2013-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A anestesia regional intravenosa (ARIV para cirurgias de membros superiores com a tradicional alta dose de lidocaína pode levar a efeitos colaterais potencialmente letais. A fim de evitar esses efeitos, muitas técnicas modificadas de ARIV foram experimentadas com o uso de uma dose baixa de lidocaína, relaxante muscular e opioide. MÉTODOS: O presente estudo foi feito com 60 pacientes não medicados previamente, com classificação ASA 1-2, para comparar as características sensoriais e motoras, os parâmetros cardiorrespiratórios e os efeitos colaterais durante o período intraoperatório e de deflação pós-torniquete entre os pacientes que receberam 40 mL de lidocaína a 0,5% (n = 30 e aqueles que receberam uma combinação de 40 mL de lidocaína a 0,25% com 0,05 mg de fentanil e 0,5 mg de vecurônio (n = 30 em ARIV para cirurgias ortopédicas de membros superiores. Os resultados foram analisados com o uso do teste t de Student pareado para identificar a significância estatística. RESULTADO: A diferença entre os dois grupos em relação ao tempo médio de início e completo bloqueio sensitivo e motor foi estatisticamente significante. Porém, houve completo bloqueio sensitivo e motor em ambos os grupos 15 minutos após a injeção da solução anestésica. CONCLUSÃO: Embora a pequena demora observada no início e na obtenção completa dos bloqueios sensitivo e motor possa, teoricamente, atrasar o início da cirurgia em 10-15 minutos, clinicamente esse tempo seria gasto na preparação do campo cirúrgico. Portanto, essa combinação pode ser usada com segurança e eficácia em anestesia regional intravenosa para cirurgias ortopédicas de membros superiores com menor possibilidade de toxicidade anestésica local.

  8. Intra-Articular Hyaluronic Acid Compared to Traditional Conservative Treatment in Dogs with Osteoarthritis Associated with Hip Dysplasia

    Directory of Open Access Journals (Sweden)

    Gabriel O. L. Carapeba

    2016-01-01

    Full Text Available The purpose of this study was to compare the efficacy of the intra-articular (IA hyaluronic acid injection to traditional conservative treatment (TCT in dogs with osteoarthritis (OA induced by hip dysplasia. Sixteen dogs were distributed into two groups: Hyal: IA injection of hyaluronic acid (5–10 mg, and Control: IA injection with saline solution (0.5–1.0 mL in combination with a TCT using an oral nutraceutical (750–1000 mg every 12 h for 90 days and carprofen (2.2 mg/kg every 12 h for 15 days. All dogs were assessed by a veterinarian on five occasions and the owner completed an assessment form (HCPI and CPBI at the same time. The data were analyzed using unpaired t test, ANOVA, and Tukey’s test (P<0.05. Compared with baseline, lower scores were observed in both groups over the 90 days in the veterinarian evaluation, HCPI, and CPBI (P<0.001. The Hyal group exhibited lower scores from 15 to 90 and 60 to 90 days, in the CBPI and in the veterinarian evaluation, respectively, compared to the Control group. Both treatments reduced the clinical signs associated with hip OA. However, more significant results were achieved with intra-articular hyaluronic acid injection.

  9. Modulation of Synovial Fluid-Derived Mesenchymal Stem Cells by Intra-Articular and Intraosseous Platelet Rich Plasma Administration

    Directory of Open Access Journals (Sweden)

    Emma Muiños-López

    2016-01-01

    Full Text Available The aim of this study was to evaluate the effect of intra-articular (IA or a combination of intra-articular and intraosseous (IO infiltration of Platelet Rich Plasma (PRP on the cellular content of synovial fluid (SF of osteoarthritic patients. Thirty-one patients received a single infiltration of PRP either in the IA space (n=14 or in the IA space together with two IO infiltrations, one in the medial femoral condyle and one in the tibial plateau (n=17. SF was collected before and after one week of the infiltration. The presence in the SF of mesenchymal stem cells (MSCs, monocytes, and lymphocytes was determined and quantified by flow cytometry. The number and identity of the MSCs were further confirmed by colony-forming and differentiation assays. PRP infiltration into the subchondral bone (SB and the IA space induced a reduction in the population of MSCs in the SF. This reduction in MSCs was further confirmed by colony-forming (CFU-F assay. On the contrary, IA infiltration alone did not cause variations in any of the cellular populations by flow cytometry or CFU-F assay. The SF of osteoarthritic patients contains a population of MSCs that can be modulated by PRP infiltration of the SB compartment.

  10. Management of Intra-Articular Distal Radius Fractures: Volar or Dorsal Locking Plate-Which Has Fewer Complications?

    Science.gov (United States)

    Abe, Yoshihiro; Tokunaga, Susumu; Moriya, Takuro

    2017-11-01

    The aim of this study was to compare the functional outcomes and complications of volar and dorsal plating for the management of intra-articular distal radius fractures, with special regard to indications for dorsal plating. Furthermore, we examine the rationale for choosing dorsal plating and its frequency of use. Clinical assessments included range of motion measurements at the wrist; grip strength; the Quick Disabilities of the Arm, Shoulder, and Hand score; and the Gartland and Werley score. Clinical results were compared with those achieved using a volarly placed locking plate system. According to Lutsky's plate theory, the rationale for choosing dorsal plating was based on 4 types of pathologic fractures. Of 112 patients, 38 patients were treated with open reduction internal fixation via a dorsal approach and 68 patients were treated using a volar approach. Except for wrist flexion, there were no other statistical differences in the clinical results between groups for both subjective and objective parameters. There were no statistically significant differences in the complication rates between the volar and dorsal plated groups. One serious complication occurred after volar plating. The most common reason for choosing dorsal plating was irreducible dorsal die-punch fractures. The treatment of displaced intra-articular distal radius fractures with a dorsally versus a volarly placed interlocking plate system demonstrated similar clinical results. Postoperative complications were not readily observed in the patients treated with a dorsal locking plate. Certain fracture patterns are more appropriately stabilized using a dorsal plate fixation.

  11. Inflammatory effects of autologous, genetically modified autologous, allogeneic, and xenogeneic mesenchymal stem cells after intra-articular injection in horses.

    Science.gov (United States)

    Pigott, J H; Ishihara, A; Wellman, M L; Russell, D S; Bertone, A L

    2013-01-01

    To compare the clinical and inflammatory joint responses to intra-articular injection of bone marrow-derived mesenchymal stem cells (MSC) including autologous, genetically modified autologous, allogeneic, or xenogeneic cells in horses. Six five-year-old Thoroughbred mares had one fetlock joint injected with Gey's balanced salt solution as the vehicle control. Each fetlock joint of each horse was subsequently injected with 15 million MSC from the described MSC groups, and were assessed for 28 days for clinical and inflammatory parameters representing synovitis, joint swelling, and pain. There were not any significant differences between autologous and genetically modified autologous MSC for synovial fluid total nucleated cell count, total protein, interleukin (IL)-6, IL-10, fetlock circumference, oedema score, pain-free range-of-motion, and soluble gene products that were detected for at least two days. Allogeneic and xenogeneic MSC produced a greater increase in peak of inflammation at 24 hours than either autologous MSC group. Genetically engineered MSC can act as vehicles to deliver gene products to the joint; further investigation into the therapeutic potential of this cell therapy is warranted. Intra-articular MSC injection resulted in a moderate acute inflammatory joint response that was greater for allogeneic and xenogeneic MSC than autologous MSC. Clinical management of this response may minimize this effect.

  12. Osteoarthritis in horses - Part 2: a review of the intra-articular use of corticosteroids as a method of treatment

    Directory of Open Access Journals (Sweden)

    Maria Verônica de Souza

    Full Text Available ABSTRACT: The problem considered in this review is related to the frequent use of corticosteroids (COs (i.e. steroids in the practice of equine medicine and surgery as a therapeutic strategy in the treatment of degenerative joint disease, commonly known as osteoarthritis (OA. This disease is one of the most common among the equine musculoskeletal diseases, and is clinically characterized by pain, lameness, joint effusion at the initial stage, which usually reduces with the progression of the disease, and reduced physical performance. Although steroids are considered excellent drugs in the control of clinical signs resulting from osteoarthritis, they also influence cellular activity through activation of various signaling mechanisms. However, they can cause adverse effects when administered intra-articularly, since they are immunosuppressive drugs of many cell types. They are also incriminated as suppressors of the chondrocyte matrix synthetic activities, which may contribute to 'arthropathy by corticosteroids', which can also be associated with cumulative injury resulting from improper use (dose and frequency of application of already damaged joints. The objective of this article is to review information about the advantages and disadvantages of intra-articular COs for treatment of the disease in horses. In addition, some important information of other species is also presented.

  13. Synovial response to intraarticular injections of hyaluronate in frozen shoulder. A quantitative assessment with dynamic magnetic resonance imaging

    International Nuclear Information System (INIS)

    Tamai, Kazuya; Mashitori, Hirotaka; Ohno, Wataru; Hamada, Jun'ichiro; Sakai, Hiroya; Saotome, Koichi

    2004-01-01

    To clarify the response of frozen shoulder (FS) to intraarticular injections of high-molecular-weight sodium hyaluronate (HA), a mixture of 2.5 ml of HA and 1.5 ml of 1% lidocaine was injected into the glenohumeral joint of 11 patients with FS, 8 of whom received five weekly injections. The patients were assessed using the Japanese Orthopaedic Association shoulder score (JOA score) before the first injection, 1 week after the first injection, and 1 week after the final injection. Following each clinical evaluation, the patients underwent dynamic magnetic resonance imaging enhanced with Gd-DTPA, and the coefficient of enhancement (CE) in the glenohumeral synovium was calculated, with the examiners blinded to the clinical information. The JOA score tended to be greater and the CE smaller after injection than before injection. The changes in the CE following both single and repeated injections were negatively correlated with changes in the JOA score. Thus, clinical improvement in patients with FS was associated with a decrease in the CE. Because the CE depends on the degree of synovitis, the therapeutic effect of intraarticular HA injection for FS results, at least in part, from suppression of synovitis in the glenohumeral joint through an antiinflammatory effect. (author)

  14. Choice of intra-articular injection in treatment of knee osteoarthritis: platelet-rich plasma, hyaluronic acid or ozone options.

    Science.gov (United States)

    Duymus, Tahir Mutlu; Mutlu, Serhat; Dernek, Bahar; Komur, Baran; Aydogmus, Suavi; Kesiktas, Fatma Nur

    2017-02-01

    This study was performed to compare the efficacy of treatment in three groups of patients with knee osteoarthritis (OA) given an intra-articular injection of platelet-rich plasma (PRP), hyaluronic acid (HA) or ozone gas. A total of 102 patients with mild-moderate and moderate knee OA who presented at the polyclinic with at least a 1-year history of knee pain and VAS score ≥4 were randomly separated into three groups. Group 1 (PRP group) received intra-articular injection of PRP × 2 doses, Group 2 (HA group) received a single dose of HA, and Group 3 (Ozone group) received ozone × four doses. Weight-bearing anteroposterior-lateral and Merchant's radiographs of both knees were evaluated. WOMAC and VAS scores were applied to all patients on first presentation and at 1, 3, 6 and 12 months. At the end of the 1st month after injection, significant improvements were seen in all groups. In the 3rd month, the improvements in WOMAC and VAS scores were similar in Groups 1 and 2, while those in Group 3 were lower (p injections, as the application alone was sufficient to provide at least 12 months of pain-free daily living activities. Therapeutic study, Level I.

  15. Hyaluronic acid versus saline intra-articular injections for amelioration of chronic knee osteoarthritis: A canine model.

    Science.gov (United States)

    Pashuck, Troy D; Kuroki, Keiichi; Cook, Cristi R; Stoker, Aaron M; Cook, James L

    2016-10-01

    The objective of this study was to assess the safety and efficacy of intra-articular injections of hyaluronic acid (HA) versus saline for symptomatic treatment of osteoarthritis (OA). Twenty-five adult purpose-bred dogs underwent meniscal release of one knee. Clinical, arthroscopic, and radiographic signs of OA were confirmed in all dogs prior to treatment. Dogs were randomized into five groups: HA-1 (n = 5), HA-3 (n = 5), HA-5 (n = 5), Saline-1 (n = 5), and Saline-3 (n = 5). Each dog received intra-articular injections of the respective substance into the affected knee at the pre-determined time points. Dogs were assessed for heat, swelling, and erythema after each injection and for lameness, pain, effusion, range of motion, kinetics, radiographic OA scoring, and arthroscopic scoring prior to treatment and for 6 months after injection. Dogs were then humanely euthanatized and the knees assessed grossly and histologically. Only mild heat, swelling, and/or erythema were noted in some dogs following injection and resolved within 1 week. Dogs treated with HA-1, HA-3, and HA-5 were significantly (p injection protocols were safe, superior to saline for short-term amelioration of symptoms associated with chronic OA, and can be translated to human OA treatment. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:1772-1779, 2016. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  16. Hyaluronic acid-coated bovine serum albumin nanoparticles loaded with brucine as selective nanovectors for intra-articular injection

    Directory of Open Access Journals (Sweden)

    Chen Z

    2013-10-01

    Full Text Available Zhipeng Chen,* Juan Chen,* Li Wu, Weidong Li, Jun Chen, Haibo Cheng, Jinhuo Pan, Baochang CaiDepartment of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China*These authors contributed equally to this workObjective: To evaluate the potential of hyaluronic acid (HA-coated bovine serum albumin nanoparticles (BSANPs as a novel chondrocyte-targeting drug-delivery nanomedicine.Methods: The HA-BSANPs were characterized by dynamic light scattering, transmission electron microscopy, differential scanning calorimetry, and X-ray diffraction. Fluorescence imaging was used to visualize the distribution of nanoparticles after intra-articular injection. The chondrocyte-targeting efficiency and cellular uptake mechanism of HA-BSANPs were investigated using endocytic inhibitors.Results: HA-BSANPs were successfully prepared with HA coating the surface and amorphous drug in the core. Compared with BSANPs, HA-BSANPs exhibited improved uptake by chondrocytes through a receptor-mediated active uptake mechanism. The endocytosis process of BSANPs and HA-BSANPs involved clathrin-mediated endocytosis, caveolae-mediated endocytosis, and macropinocytosis. No apparent thickening or hyperplasia of the synovium was observed in either BSANPs or HA-BSANPs. The HA-BSANPs could reside in the articular cavity of rats for more than 14 days, which was significantly longer than BSANPs.Conclusion: HA-BSANPs are a promising carrier for articular-related diseases due to elongated articular residence and improved chondrocytic accumulation.Keywords: chondrocyte, intra-articular injection, hyaluronic acid, BSA, nanoparticles

  17. Evaluation of remission of temporomandibular joints pain as a result of treatment of dysfunction using intraarticular injection.

    Science.gov (United States)

    Pihut, Małgorzata; Górecka, Małgorzata; Ceranowicz, Piotr

    2017-01-01

    The temporomandibular joint pain, which occurs in the course of temporomandibular joint dysfunction, is one of the main clinical problems in the treatment of joint disc displacement. The aim of the study was to evaluate changes in temporomandibular joints pain in treatment supporting disc displacement without reduction using intra-articular injection of hyaluronic acid and platelet-rich plasma. The study consisted of a group of 60 patients, aged 35-49, who reported for treatment, because of pain in the preauricural area. The functional examination stated disk dicplacement without reduction, along with the accompanying pain of temporomandibular joints. Patients were treated between January 2015 and February 2017. They were divided into two groups of 30 persons. The intraarticular injection of hyaluronic acid was administered in the I-test group, and the injection of platelet-rich plasma in the control group. This treatment was carried out parallel to the use of repositioning splits. Analysis of regression of symptoms other than intensity of pain during the treatment, evaluated in this study shows a decrease of individual symptoms, but the results of the regression of pain between two groups did not differ statistically significantly, because "p" is bigger than 0.05. The results of the research show the clinical benefits of application of hyaluronic acid and plate rich plasma in the treatment of temporomandibular joint dysfunction.

  18. Changes in concentrations of haemostatic and inflammatory biomarkers in synovial fluid after intra-articular injection of lipopolysaccharide in horses

    DEFF Research Database (Denmark)

    Andreassen, Stine Mandrup; Vinther, Anne Mette Lindberg; Nielsen, Søren Saxmose

    2017-01-01

    BACKGROUND: Septic arthritis is a common and potentially devastating disease characterized by severe intra-articular (IA) inflammation and fibrin deposition. Research into equine joint pathologies has focused on inflammation, but recent research in humans suggests that both haemostatic and inflam......BACKGROUND: Septic arthritis is a common and potentially devastating disease characterized by severe intra-articular (IA) inflammation and fibrin deposition. Research into equine joint pathologies has focused on inflammation, but recent research in humans suggests that both haemostatic...... and inflammatory pathways are activated in the joint compartment in arthritic conditions. The aim of this study was to characterize the IA haemostatic and inflammatory responses in horses with experimental lipopolysaccharide (LPS)-induced joint inflammation. Inflammation was induced by IA injection of LPS into one...... antebrachiocarpal joint of six horses. Horses were evaluated clinically with subjective grading of lameness, and blood and synovial fluid (SF) samples were collected at post injection hours (PIH) -120, -96, -24, 0, 2, 4, 8, 16, 24, 36, 48, 72 and 144. Total protein (TP), white blood cell counts (WBC), serum amyloid...

  19. Contribution of 3-T Susceptibility-Weighted MRI to Detection of Intraarticular Hemosiderin Accumulation in Patients With Hemophilia.

    Science.gov (United States)

    Akyuz, Behic; Polat, Ahmet Veysel; Ozturk, Mesut; Aslan, Kerim; Tomak, Leman; Selcuk, Mustafa Bekir

    2018-02-22

    The purpose of this study was to assess the feasibility of 3-T susceptibility-weighted imaging (SWI) for detecting intraarticular hemosiderin accumulation in patients with hemophilia. Forty-one joints in 24 patients with hemophilia were imaged with conventional MRI and SWI sequences. Two experienced musculoskeletal radiologists and one general radiologist (reader 3) interpreted the images for hemosiderin accumulation. The final decision was determined in consensus by readers 1 and 2 using both conventional MRI and SWI sequences. The diagnostic consistencies of each MRI sequence with the reference and pairwise agreements between interpreters were assessed. For conventional MRI sequences, the diagnostic consistencies of the two experienced musculoskeletal radiologists with the reference were substantial (κ = 0.63 and 0.62), whereas the consistency of the general radiologist with the reference was moderate (κ = 0.47). The SWI interpretations of all readers had almost perfect agreement with the reference (κ = 1, κ = 1, κ = 0.97). Interobserver agreement also improved at SWI interpretations. SWI contributes to more accurate grading of intraarticular hemosiderin accumulation than is achieved with conventional MRI sequences.

  20. Biomechanical comparison of locking plate and crossing metallic and absorbable screws fixations for intra-articular calcaneal fractures.

    Science.gov (United States)

    Ni, Ming; Wong, Duo Wai-Chi; Mei, Jiong; Niu, Wenxin; Zhang, Ming

    2016-09-01

    The locking plate and percutaneous crossing metallic screws and crossing absorbable screws have been used clinically to treat intra-articular calcaneal fractures, but little is known about the biomechanical differences between them. This study compared the biomechanical stability of calcaneal fractures fixed using a locking plate and crossing screws. Three-dimensional finite-element models of intact and fractured calcanei were developed based on the CT images of a cadaveric sample. Surgeries were simulated on models of Sanders type III calcaneal fractures to produce accurate postoperative models fixed by the three implants. A vertical force was applied to the superior surface of the subtalar joint to simulate the stance phase of a walking gait. This model was validated by an in vitro experiment using the same calcaneal sample. The intact calcaneus showed greater stiffness than the fixation models. Of the three fixations, the locking plate produced the greatest stiffness and the highest von Mises stress peak. The micromotion of the fracture fixated with the locking plate was similar to that of the fracture fixated with the metallic screws but smaller than that fixated with the absorbable screws. Fixation with both plate and crossing screws can be used to treat intra-articular calcaneal fractures. In general, fixation with crossing metallic screws is preferable because it provides sufficient stability with less stress shielding.

  1. MANAGEMENT OF PRIMARY FROZEN SHOULDER PROSPECTIVE EVALUATION OF FUNCTIONAL OUTCOME BETWEEN HYDRODILATATION AND INTRA-ARTICULAR STEROID INJECTION

    Directory of Open Access Journals (Sweden)

    Dinesh Mitra R. P

    2017-01-01

    Full Text Available BACKGROUND The aim of this prospective randomized control study is to compare the functional outcome between hydrodilatation and intraarticular steroid injection in patients with primary frozen shoulder. MATERIALS AND METHODS A total number of 52 patients who attended the orthopaedic outpatient between November 2014 and January 2016 were included in this study. The patients were categorized into two groups. Group I patients were treated with hydrodilatation method and Group II patients were treated with intra-articular steroids. Both the group of patients were advised to perform home exercise programs. The patients were assessed at baseline (before the procedure at two weeks, six weeks, three months and six months. All patients were evaluated for functional improvement by measuring the range of active movements and Constant and Murley shoulder outcome scores. RESULTS Up to three months patients treated with hydrodilatation have significantly better functional outcome as evaluated by active range of movements and Constant and Murley score. But at six months there is no significant difference in functional outcome between two methods of treatment. CONCLUSION There was improvement in functional outcome in both the methods of treatment. But patients treated by hydrodilatation showed more significant increase in functional outcome for the first three months. Home exercise forms an integral part in the management of primary frozen shoulder.

  2. Estudo comparativo entre soluções a 0,5% de levobupivacaína, bupivacaína em excesso enantiomérico de 50% e bupivacaína racêmica em anestesia peridural para cirurgia de abdômen inferior Estudio comparativo entre soluciones a 0,5% de levobupivacaína, bupivacaína en exceso enantiomérico del 50% y bupivacaína racémica en anestesia peridural para cirugía de abdomen inferior Levobupivacaine 0.5%, 50% enantiomeric excess bupivacaine and racemic bupivacaine in epidural anesthesia for lower abdominal procedures. Comparative study

    Directory of Open Access Journals (Sweden)

    Pedro Paulo Tanaka

    2005-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Com a finalidade de encontrar um anestésico local mais seguro que a bupivacaína, vários estudos em animais foram realizados com seus isômeros. Este estudo teve como objetivo avaliar a eficácia da bupivacaína em excesso enantiomérico de 50%, comparada à levobupivacaína e à bupivacaína racêmica, na anestesia peridural em pacientes submetidos à cirurgia de abdômen inferior, pelo período de uma hora após a injeção das soluções. MÉTODO: Após aprovação pelo Comitê de Ética em Pesquisa, participaram deste estudo, aleatório e duplamente encoberto, 87 pacientes com idade entre 18 e 65 anos, estado físico ASA I e II submetidos à cirurgia de abdômen inferior. Foram distribuídos em três grupos que receberam fracionadamente solução contendo 27 mL (incluindo a dose-teste de anestésico local com adrenalina (1:200.000 e fentanil (100 µg. O grupo I recebeu solução de levobupivacaína a 0,5%, o grupo II recebeu solução de bupivacaína em excesso enantiomérico de 50% a 0,5% e o grupo III recebeu solução de bupivacaína a 0,5%. Os pacientes foram monitorizados por meio de oxímetro de pulso, cardioscópio e pressão arterial não-invasiva. Foram investigadas as características motoras e sensitivas do bloqueio anestésico, bem como a incidência de efeitos colaterais. Os frascos de anestésico local foram preparados sem identificação, numerados e somente ao final do estudo a lista de distribuição aleatória foi aberta. RESULTADOS: Não foram observadas diferenças significativas com relação à altura e estado físico. Diferença demográfica significativa foi encontrada em relação à idade no grupo I. Os parâmetros hemodinâmicos foram semelhantes entre os grupos. Houve diferença significativa em relação à intensidade do bloqueio motor relatado entre os grupos estudados (menor intensidade no grupo I comparada aos grupos II e III. CONCLUSÕES: Foram observados adequados bloqueios

  3. A new co-ordinated research project on 'Comparative Evaluation of the Efficacy of Radiosynovectomy with Conventional Intra-articular Therapy in Rheumatoid Arthritis and Haemophilic Arthropathy (CERAHA)'

    International Nuclear Information System (INIS)

    Barrenechea, E.; Amaral, H.

    2003-01-01

    Radionuclide synovectomy with various radiopharmaceuticals has been used to alleviate the pain and swelling of rheumatoid arthritis and related joint diseases for more than 40 years. Radiocolloids labeled with Au-198, Y-90, P-32, Re-186, and Re-188, Dy-165, Ho-166 in large joints have been used and clinical improvement has been reported in 48-75% of treated joints. In small joints use of Er- 169 has been shown to be effective. In osteoarthritis, due to bone destruction, results of radiation synovectomy have been relatively poor. Synovectomy is indicated in patients with progressive inflammatory signs and symptoms intractable to medical therapy including local intra-articular steroid injection. Chemical synovectomy using rifampicin or corticosteroids has been used as the first line treatment with limited success. Surgical synovectomy has also been used as an alternative treatment modality. However, the long recovery period, expense, technical difficulty and postsurgical complications, provide clear incentives to explore other forms of treatment such as radionuclide synovectomy. Intra articular administration of radiocolloids is also beneficial in 80% of haemophilia patients and offers a much simpler and safer alternative to surgery in coagulation compromised patients. However, even though it is clear that radiation synovectomy is efficacious in controlling the symptoms of rheumatoid arthritis and for preserving function in haemophilia haemarthroses, there is a paucity of well-controlled trials and rigorous clinical follow-up in large series of patients. Rheumatoid arthritis and Haemophilia are common diseases worldwide but management of the associated Arthropathy is often compromised in developing countries by high cost and limited availability of specialized treatments. In developing countries, in centres practicing radiation synovectomy for both chronic rheumatoid arthritis and in repeated haemarthroses in haemophilia, exemplary results have been achieved. The

  4. Operative versus nonoperative treatment of displaced intra-articular calcaneal fractures

    Science.gov (United States)

    Wei, Ning; Yuwen, Peizhi; Liu, Wei; Zhu, Yanbin; Chang, Wenli; Feng, Chen; Chen, Wei

    2017-01-01

    Abstract Background: The relative efficacy of operative and nonoperative treatments for the displaced intra-articular calcaneal fractures (DIACF) remains uncertain. Object: We conducted a meta-analysis to compare the effectiveness of operative and nonoperative treatments in treating patients with DIACF. Methods: Databases including Cochrane Library, Medline, Embase, CBM, CNKI, and Google Scholar were searched. After independent study selection by 2 authors, data were extracted and collected independently. Comparisons were performed between operative treatment group and nonoperative treatment group. The quality of included studies was assessed using the Newcastle–Ottawa Scale. RevMan 5.3 was used for data analysis. The primary outcome measures were anatomical measures (changes in Böhler angle and calcaneal height and width), functional measures (shoe problems, resuming preinjury work, and residual pain), and complications (including superficial and deep wound infection, skin flap necrosis, neurovascular injury, secondary arthrodesis, reflex sympathetic dystrophy, osteotomy, thromboembolism, and compartment syndromes). Results: Eighteen trials (8 randomized controlled trials and 10 controlled clinical trials) including 1467 patients were considered. For anatomical measurements, the overall mean differences (MDs) for the mean Böhler angle, calcaneal height and width were 15.39 (95% confidence interval [CI] 9.12–21.67), 6.55 (95% CI 2.67–10.43), and 7.05 (95% CI −7.83 to −6.27), respectively. In functional measures, the overall effect MD of American Orthopedic Foot and Ankle Society was 6.23 (95% CI 5.22–17.67) and 0.38 (95% CI 0.22–0.67). The overall relative risks (RRs) of wearing shoes, resuming preinjury work, and having residual pain were 0.32 (95% CI 0.32–1.00), 0.56 (95% CI 0.40–0.77), and 0.90 (95% CI 0.68–1.20), respectively. The overall RR of the incidence of complications was 2.00 (95% CI 1.51–2.64). Conclusion: Operative treatment of

  5. Product Differences in Intra-articular Hyaluronic Acids for Osteoarthritis of the Knee.

    Science.gov (United States)

    Altman, Roy D; Bedi, Asheesh; Karlsson, Jon; Sancheti, Parag; Schemitsch, Emil

    2016-08-01

    Knee osteoarthritis (OA) is a common and often disabling joint disorder among adults that may result in impaired activity and daily function. A variety of treatment options are currently available and prescribed for knee OA depending on the severity of the disorder and physician preference. Intra-articular hyaluronic acid (IA-HA) injection is a treatment for knee OA that reportedly provides numerous biochemical and biological benefits, including shock absorption, chondroprotection, and anti-inflammatory effects within the knee. Clarity is needed as to whether the available IA-HA products should be considered for therapy as a group or whether there are significant differences in the products that need to be considered in treatment of OA of the knee. To determine whether there are differences in efficacy and safety with respect to intrinsic properties of available IA-HA injections for knee OA. Meta-analysis. A comprehensive literature search of the Medline, EMBASE, and PubMed databases was conducted for all existing randomized trials of IA-HA. The primary outcome measure analyzed was the mean pain score at the reported follow-up nearest to 26 weeks after injection. Pooled efficacy and safety results were recorded for subgroupings of HA product characteristics. A total of 68 studies were included for analysis. Products with an average molecular weight ≥3000 kDa provided favorable efficacy results when compared with products of an average molecular weight injection site than did avian-derived HA products, while high-molecular-weight products demonstrated the highest rate of injection site flare-up. Despite similarities, IA-HA products should not be treated as a group, as there are differences in IA-HA products that influence both efficacy and safety. In the available literature, IA-HA products with a molecular weight ≥3000 kDa and those derived from biological fermentation relate to superior efficacy and safety-factors that may influence selection an IA-HA product

  6. [Iontophoresis - local anesthesia at the ear canal and tympanic membrane (author's transl)].

    Science.gov (United States)

    Tolsdorff, P

    1980-02-01

    Operations to the external ear canal and tympanic membrane necessitate sufficient local anesthesia. General sedation followed by infiltration anestesia, is rather time-consumming, can be painful due to the injection, and is not particularly satisfactory for the treatment of outpatients. The iontophorese-technique, however, of local anesthesia, is applicable particularly for the treatment of outpatients. Principally, the local anesthetic is transported in ionisised form to the nerve membrane, by means of calvanic currents through the healthy surface epithelial tissue of the external ear canal or the eardrum. The technique described for the first time in 1911 no longer shows toxic sides-effects since the introduction of improved electrodes and more modern local anesthetic. The anatomic, pharmacological, chemical and physical basics of the technique will be described. The lecture will be based on personal experience of the method, taken from large groups of patients over a period of more than two years, using equipment specially designed for this purpose.

  7. Intra-articular injection of an antioxidant formulation did not improve structural degeneration in a rat model of post-traumatic osteoarthritis

    Directory of Open Access Journals (Sweden)

    Yau-Chuk Cheuk

    2017-01-01

    Conclusion: Intra-articular injection of an antioxidant formulation containing quercetin, vitamin C, and deferoxamine did not retard OA progression in advanced-stage OA. Future studies should aim to determine whether giving antioxidants in early OA, with prolonged drug retention, would be effective in retarding OA progression.

  8. A randomised controlled trial for the effectiveness of intra-articular Ropivacaine and Bupivacaine on pain after knee arthroscopy: the DUPRA (DUtch Pain Relief after Arthroscopy)-trial

    NARCIS (Netherlands)

    Campo, M. M.; Kerkhoffs, G. M. M. J.; Sierevelt, I. N.; Weeseman, R. R.; van der Vis, H. M.; Albers, G. H. R.

    2012-01-01

    In this double-blinded, randomised clinical trial, the aim was to compare the analgesic effects of low doses of intra-articular Bupivacaine and Ropivacaine against placebo after knee arthroscopy performed under general anaesthesia. A total of 282 patients were randomised to 10 cc NaCl 0.9%, 10 cc

  9. Short- and long-term efficacy of intra-articular injections with betamethasone as part of a treat-to-target strategy in early rheumatoid arthritis

    DEFF Research Database (Denmark)

    Hetland, Merete Lund; Østergaard, Mikkel; Ejbjerg, Bo

    2012-01-01

    OBJECTIVE: To investigate the short-term and long-term efficacy of intra-articular betamethasone injections, and the impact of joint area, repeated injections, MRI pathology, anticyclic citrullinated peptide (CCP) and immunoglobulin M rheumatoid factor (IgM-RF) status in patients with early...

  10. Addition of intra-articular hyaluronate injection to physical therapy program produces no extra benefits in patients with adhesive capsulitis of the shoulder: a randomized controlled trial.

    Science.gov (United States)

    Hsieh, Lin-Fen; Hsu, Wei-Chun; Lin, Yi-Jia; Chang, Hsiao-Lan; Chen, Chiao-Chien; Huang, Vincent

    2012-06-01

    To compare the efficacy of intra-articular hyaluronic acid (HA) injections plus physical therapy (PT) with that of PT alone for the treatment of adhesive capsulitis (AC) of the shoulder. Prospective, randomized controlled trial. Rehabilitation and orthopedics department of a private teaching hospital. Patients (N=70) with AC of the shoulder were randomly placed into either of the following treatment groups: group 1, HA injections with PT (HAPT group); or group 2, PT alone (PT group). The patients in group 1 received intra-articular glenohumeral joint injections of HA, 20mg, once per week for 3 consecutive weeks and also participated in a PT program for 3 months. The patients in group 2 received PT alone. Active and passive range of motion (ROM) of the affected shoulder, pain, disability, and quality of life. Both groups experienced improvements in terms of pain, disability, and quality of life after the treatments; furthermore, the active and passive ROM improved linearly with increasing treatment duration. When the groups were compared, no significant group effect was found for any of the outcome measurements. Intra-articular HA injections did not produce added benefits for patients with AC of the shoulder who were already receiving PT. Thus, the use of intra-articular HA injections for patients with AC of the shoulder should be carefully assessed to reduce unnecessary medical expenditures. Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  11. Intra-articular treatment with triamcinolone compared with triamcinolone with hyaluronate : A randomised open-label multicentre clinical trial in 80 lame horses

    NARCIS (Netherlands)

    de Grauw, J. C.; Visser-Meijer, M. C.; Lashley, F.; Meeus, P.; van Weeren, P. R.

    2016-01-01

    REASONS FOR PERFORMING STUDY: Intra-articular (IA) injection of corticosteroids with or without hyaluronate (HA) has been used for decades in equine practi