Estado de los micronutrientes hierro y vitamina A, factores de riesgo para las deficiencias y valoración antropométrica en niños preescolares del municipio de Funza, Colombia

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Elpidia Poveda

2007-03-01

Conclusión. Existe la necesidad de fortalecer programas fundamentados en las condiciones existentes para mejorar la situación nutricional de los preescolares del municipio de Funza. Es importante indagar si se presenta anemia nutricional relacionada con ácido fólico y vitamina B12, así como sobre otros factores de riesgo asociados con la deficiencia nutricional por hierro y vitamina A.

Deficiencia de zinc y sus implicaciones funcionales

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ROSADO JORGE L

1998-01-01

El presente trabajo tiene por objeto revisar los aspectos teóricos y los estudios realizados en México que sugieren la existencia de la deficiencia moderada de zinc en niños de población rural, así como algunas de las consecuencias de dicha deficiencia en la salud. El zinc es un nutrimento indispensable para el organismo de los humanos y juega un papel importante en una serie de procesos metabólicos: participa en el sitio catalítico de varios sistemas enzimáticos; participa como ion estructur...

Nutritional causes of anemia in Mexican children under 5 years: results from the 2006 National Health and Nutrition Survey Causas nutricionales de anemia en niños menores de 5 años: resultados de la Encuesta Nacional de Salud y Nutrición 2006

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Vanessa De la Cruz-Góngora

2012-04-01

Full Text Available OBJECTIVE: To describe the frequency and severity of anemia and the nutritional variables associated to hemoglobin levels (Hb in children OBJETIVO: Describir las causas y severidad de la anemia y los factores nutricionales asociados con hemoglobina en niños anémicos <5 años. MATERIAL Y MÉTODOS: Estudiamos los niveles de hemoglobina y las concentraciones séricas de ferritina, receptores solubles de transferrina, proteína C reactiva (CRP, zinc, hierro, cobre, magnesio, vitamina B12 y folato en 981 niños. Se utilizaron modelos de regresión ordinal y regresiones lineales múltiples para evaluar el riesgo de severidad de anemia y la variabilidad en hemoglobina. RESULTADOS: La prevalencia de anemia fue de 20.6%; el 14 y 6.38% tenían anemia leve y moderada. La anemia se asoció con deficiencia de hierro (DH en 42.17%; la DH coexistió con deficiencia de folatos y vitamina B12 en 9%. Sólo 2% de la anemia se asoció con deficiencia de folatos o vitamina B12. CRP (coef: 0.17 g/dl y el tercer tercil de cobre (coef: -0.85 g/dl se asociaron con anemia sin explicar (p<0.05. CONCLUSIONES: DH es la principal causa de anemia en niños <5 años. Las concentraciones de folato y vitamina B12 se asociaron con anemia. La CRP se asoció con anemia sin explicar. Sin embargo, la deficiencia de vitamina A, que se asocia con anemia, no fue estudiada.

Anemia hemolítica autoinmune postinfección por virus de la hepatitis A. Informe de caso; Autoimmune haemolytic anaemia associated to hepatitis A. Case report

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Claudia Lucía Sossa Melo, MD

2010-01-01

Full Text Available La anemia hemolítica autoinmune se asocia con una variedad de virus hepatotrópicos, en particular citomegalovirus (CMV, virus del Epstein-Barr y de la hepatitis B. No es frecuente dentro de la historia natural de la hepatitis A, la aparición de anemia hemolítica, y cuando se presenta, generalmente se asocia a deficiencia de glucosa-6-fosfato deshidrogenasa. Presentamos el caso de un paciente de sexo masculino sin hemólisis previa, con astenia e ictericia de dos meses de evolución y hepatomegalia 14 cm por debajo del reborde costal derecho. Los hallazgos en los exámenes de laboratorios mostraron anemia hemolítica con Coombs directo positivo, anticuerpos tipo inmunoglobulina M contra el virus de la hepatitis A positivos, niveles de bilirrubinas 20 veces y aminotrasferasas cuatro veces por arriba del rango normal; con estos datos el paciente fue diagnosticado como hepatitis A complicada con anemia hemolítica y probable hepatitis autoinmune asociada, por lo que se inició manejo con corticoides, alcanzándose mejoría clínica. Resaltamos la importancia de descartar la infección por el virus de la hepatitis A como posible etiología de anemia hemolítica autoinmune.______________________________________________________________________ Acute auto inmune haemolytic anaemia is associated with a variety of hepatotropic viruses, in particular cytomegalovirus, Epstein Barr virus and hepatitis B. The typical course of hepatitis A is rarely complicated with glucose-6-phosphate dehydrogenase deficiency. Wepresent the case of a man without previous haemolysis, he had been unwell for two months with fatigue and jaundice, the liver edge was palpable and tender 14 cm below the costal margin. Clinical chemistry showed haemolytic anaemia with positive direct coombs test, immunoglobulin M antibodies to hepatitis A virus were detected, the total bilirrubin concentration 20 times the upper and transaminase 4 times upper limit for normal levels; with this

Caracterización de la anemia en niños menores de cinco años de zonas urbanas de Huancavelica y Ucayali en el Perú

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Elena Gonzales

Full Text Available Objetivos. Caracterizar la anemia en niños entre 12 a 59 meses pertenecientes a de zonas urbanas de las provincias de Huancavelica y Coronel Portillo en el Perú. Materiales y métodos. Estudio transversal desarrollado en dos etapas: a estudio de base poblacional para la identificación de niños con anemia mediante un muestreo probabilístico multietápico, y b caracterización de los niveles séricos de ferritina, vitamina B12, ácido fólico intraeritrocitario y presencia de parasitosis en los niños con anemia. Para el análisis estadístico se aplicaron los factores de expansión calculados a partir del plan de muestreo. Resultados. La prevalencia de anemia en Huancavelica fue 55,9% y en Coronel Portillo 36,2%. En Huancavelica la coexistencia de anemia con deficiencia de hierro fue del 22,8% y de anemia con deficiencia de vitamina B12 del 11%, en Coronel Portillo la coexistencia de anemia con deficiencia de hierro y déficit de vitamina B12 fueron del 15,2 y 29,7% respectivamente. Los tipos de anemia más frecuentes en Huancavelica fueron anemia concurrente con parasitosis (50,9%; anemia ferropénica y parasitosis (12,3%, y solo ferropénica (6,4%; en Coronel Portillo fue anemia y parasitosis (54,4%; deficiencia de vitamina B12 y parasitosis (18,4% y anemia ferropénica y parasitosis (6,3%. Conclusiones. La prevalencia de anemia es superior al promedio nacional, siendo la anemia concurrente con parasitosis y la anemia concurrente con dos o más causas el tipo más frecuente. Se debe considerar etiologías diferentes a la deficiencia de hierro en los programas de control de la anemia en niños peruanos

Anemia y anemia por déficit de hierro en niños menores de cinco años y su relación con el consumo de hierro en la alimentación. Turbo, Antioquia, Colombia Anemia and iron deficit anemia in children under five years of age and their relation with iron consumption in alimentation, Turbo, Antioquia, Colombia

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Gloria Margarita Alcaraz López

2006-09-01

Full Text Available Objetivo: Determinar la frecuencia de anemia y de anemia por deficiencia de hierro y su relación con el contenido de hierro en la alimentación en niños de 6 meses a 5 años. Materiales y métodos: Estudio descriptivo de corte transversal en el que se estudiaron 113 niños que asistieron a la consulta de crecimiento y desarrollo y al programa de vacunación de la ESE Hospital Francisco Valderrama de Turbo entre el mes de septiembre de 2001 y el mes de junio de 2002. Las pruebas de laboratorio empleadas fueron Hb, ferritina, coprológico directo y sangre oculta en heces. El hierro dietario se estudió con una encuesta semiestructurada. Resultados y discusión: Promedio de Hb 11,3 g/dl (DE 1,4; presentan anemia 48,7%, los más afectados fueron los menores de un año. Promedio de ferritina 47,1 µg/L (DE 58,7, mediana 23,3 µg/L.; 50,4% presentan ferritina baja y de estos, 23,9% presentan agotamiento en los depósitos de hierro. De los 55 niños con anemia 23,6% presentan anemia con deficiencia de hierro. Promedio en el consumo de hierro 7,1 mg/día (DE 3,96; promedio de hierro hemínico de 3,9 mg/día. Promedio de lactancia materna exclusiva: 3 meses. La lactancia se alterna con leche de vaca pasteurizada. De cada 10 menores de un año, 6 tienen anemia con déficit de hierro. Conclusiones: La anemia, la ferritina baja y el bajo consumo de hierro en los niños estudiados perfilan un grave problema de salud pública. Se requiere una política clara y articulada a la cultura de la población para prevenir este problema y sus secuelas en el crecimiento, el desarrollo y en la capacidad cognitiva de los niños.Objective: to determine the frequency of anemia and iron deficit anemia in relation to the iron content in the alimentation of children from 6 months to five years in Turbo. Methodology and materials: transversal descriptive study of 113 children attending the growth, development and vaccination program clinic, from September 2001 to June 2002

Trastornos Asociados a la Deficiencia de Yodo. Vigilancia permanente es deficitaria en zonas vulnerables

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Hernando Vargas-Uricoechea; Carlos Hernán Sierra-Torres; Claudia Milena Holguín Betancourt; Laura Cristancho Torres

2012-01-01

Los Desórdenes por Deficiencia de Yodo (DDY) son uno de los mayores problemas en salud pública en el mundo actual, en especial en niños y embarazadas. Estos trastornos truncan el desarrollo socioeconómico en aquellas zonas que los padecen; las poblaciones que viven en zonas yodo-deficientes siempre van a estar expuestas a sufrir las consecuencias originadas por esta deficiencia, en especial el aumento en la mortalidad perinatal, retardo mental, alteraciones en la síntesis de hormonas tiroide...

Prevalencia de anemia ferropénica en escolares y adolescentes, Medellín, Colombia, 1999 Prevalence of iron-deficiency anemia in schoolchildren and adolescents, Medellín, Colombia, 1999

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Gloria M. Agudelo

2003-06-01

Full Text Available OBJETIVO: Determinar la prevalencia de anemia ferropénica y describir el consumo de hierro en la dieta de escolares y adolescentes matriculados en colegios oficiales y privados de la zona urbana de la ciudad de Medellín, Colombia, en el año escolar 1999­2000, así como explorar la asociación entre grupo de edad, sexo, clase socioeconómica y parasitismo intestinal por un lado, y anémica ferropénica y deficiencia de hierro por el otro. MÉTODOS: Se realizó un estudio de corte transversal en 960 estudiantes de 6 a 18 años de edad que fueron elegidos por muestreo aleatorio simple tras un muestreo polietápico estratificado y por conglomerados de colegios oficiales y privados en comunas de la zona de Medellín. Se evaluaron el contenido corporal de hierro mediante determinaciones de ferritina, hemoglobina, volumen corpuscular medio y amplitud de la distribución eritrocitaria; la presencia de parásitos intestinales mediante análisis coprológico; el estado nutricional por medio de mediciones antropométricas; y el consumo de hierro y vitamina C mediante un cuestionario semicuantitativo de ingesta alimentaria. Para definir los casos de anemia ferropénica y de deficiencia de hierro se usaron las definiciones estándar de la Organización Mundial de la Salud basadas en los valores de ferritina y hemoglobina. También se examinó la asociación entre grupo de edad, sexo, clase socioeconómica y presencia de parásitos intestinales por un lado y la presencia de anemia por el otro mediante pruebas no paramétricas con un nivel de significación de 0,05. RESULTADOS: La prevalencia de deficiencia de hierro fue de 4,9% y la de anemia ferropénica, de 0,6%. Se encontró una mayor prevalencia de ambas en mujeres adolescentes (P OBJECTIVE: This research had two objectives: (1 to determine the prevalence of iron-deficiency anemia and describe iron consumption in the diet of schoolchildren and adolescents enrolled in public and private schools of the

BIENESTAR PSICOLOGICO Y ACTIVIDAD FÍSICA EN POBLACIONES CIEGAS Y CON DEFICIENCIAS VISUALES

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Alicia Santana Rodríguez

2002-06-01

Full Text Available Con el presente trabajose intenta detectar la percepción, que tienen las personas con deficiencia visual, de los beneficios producidospor la actividad física y/o el deporte. Estos beneficios percibidos por los sujetos han sido estudiados atendiendoa la edad, sexo, tipo de deficiencia y momento de aparición de la deficiencia en los mismos. El estudio decarácter eminentemente descriptivo se realizó con una muestra 130 sujetos ciegos y/o con deficiencia visual.Los resultados sugieren que los beneficios percibidos son valorados muy positivamente y representan unaamplia gama. Igualmente se aprecian ciertas diferencias atendiendo a la edad, sexo, tipo de deficiencia (total oparcial y momento de aparición de la misma (desde el nacimiento o adquirida posteriormente. Como aspectosmás concretos destacan la capacidad física, sentirse bien consigo mismo, la diversión y la relajación que supone para los sujetos.

Estudio de la deficiencia de hierro en pacientes con insuficiencia cardiaca congestiva: una práctica clínica que precisa mayor atención

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Lara Belmar Vega

2016-05-01

Conclusión: La ICC se asocia con alta frecuencia a anemia, deficiencia de hierro e insuficiencia renal. El estudio de los parámetros férricos en los pacientes que ingresan con ICC, pese a que la corrección de la deficiencia de hierro se asocia a mejoría de la sintomatología, no se realiza con la frecuencia necesaria.

Trastornos por deficiencia de Yodo. Programa de yodización en Colombia y América Latina.

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Alfredo Jácome Roca

2001-08-01

Full Text Available

El halógeno yodo es un elemento definitivo para el buen funcionamiento de la glándula tiroides y para la formación de las hormonas tiroideas; estas son esenciales para el desarrollo del sistema nervioso central, para el crecimiento, para la termogénesis y para una serie de funciones adicionales sobre el metabolismo como por ejemplo la absorción de la glucosa. Los trastornos por deficiencia de yodo los llamaremos aquí por las siglas DDI, del inglés “Iodine deficiency disorders”.

Aún en situaciones de marcada yodo-deficiencia, la glándula tiroides es capaz de extraer la máxima cantidad de este elemento de la sangre(hasta 40 veces su concentración, pues está dotada de un mecanismo de transporte activo relacionado con la bomba de sodio, donde la absorción de yodo se logra de una manera parásita al sodio. Se encuentra en forma de yoduros o de yodo elemental y una vez atrapado, este sufre una serie de transformaciones dentro de la glándula conocidas como tiroxinogénesis, con etapas de oxidación, organificación y acoplamiento, lo que da lugar a la formación de las dos hormonas tiroideas, la tiroxina o T4 y la triyodotironina o T3.

Todos estos procesos se encuentran en buena parte regulados por la hormona tirotropa o TSH, la que también es la responsable de la liberación gradual de las hormonas depositadas en la glándula, la cual se produce a medida que van disminuyendo los niveles de T4 y de T3 en su forma libre, que son las que interactúan con los diversos receptores para ejercer su acción fisiológica(1.

La carencia de yodo produce una serie de trastornos como la aparición de bocio en los individuos, además de hipotiroidismo; en las embara adas se producen abortos, niños que nacen muertos o que nacen con retardo mental; estos niños cretinos tienen además enanismo y otras alteraciones físicas, lo que los lleva a una baja productividad con una alta demanda de servicios sociales, constituyéndose en

Prevalencia y factores sociodemográficos asociados a la deficiencia de ferritina en niños de Colombia, 2010

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Robinson Ramírez-Vélez

Full Text Available Objetivos. Determinar la prevalencia y los factores sociodemográficos asociados a la deficiencia de ferritina en una muestra representativa de niños de Colombia. Materiales y métodos. Análisis secundario transversal de la Encuesta Nacional de la Situación Nutricional (ENSIN realizada en Colombia el año 2010 en 3542 infantes entre 12 y 59 meses de edad. Los niveles plasmáticos de ferritina se determinaron por quimioluminiscencia y se consideraron como déficit de ferritina los valores < 12 µg/L, los factores sociodemográficos (sexo, edad, etnia, nivel socioeconómico, región y área geográfica se recogieron mediante una encuesta estructurada. Todos los análisis se realizaron teniendo en cuenta la naturaleza compleja de la muestra. Resultados. Se encontró que el valor promedio de ferritina fue de 32,1 µg/L, (IC 95%: 30,7-35,6. El 10,6% (IC 95%: 9,3-12,0 de los niños presentaron niveles de ferritina menores a 12,0 µg/L. La regresión logística multivariable muestra que los niños de 12 a 23 (OR 5,1; IC 95%: 3,3-8,0 y 24 a 35 meses de edad (OR 2,4; IC 95%: 1,5-3,7, pertenecer al grupo étnico indígena (OR 1,8; IC 95%: 1,1-2,8, residir en la zona atlántico (OR 2,0; IC 95%: 1,1-3,6, o zona pacifica (OR 2,0; IC 95%: 1,1-3,6 se asociaron a una mayor probabilidad de presentar deficiencias de ferritina. Conclusiones. Se encontró una importante prevalencia de anemia por deficiencia de ferritina y diversos factores sociodemográficos contribuyeron con la probabilidad de incrementar este problema. Se recomienda intervenciones integrales donde estén involucrados los componentes nutricional y educativo

Prevalencia de deficiencia de hierro y yodo, y parasitosis en niños de Arandas, Jalisco, México

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Vásquez-Garibay Edgar Manuel

2002-01-01

Full Text Available Objetivo. Estimar la prevalencia de deficiencia de hierro, yodo y parasitosis en niños que asisten al Instituto Alteño para el Desarrollo de Jalisco (Inadej, Arandas, Jalisco, México. Material y métodos. Estudio transversal efectuado entre 1997 y 1999 con 432 niños de 12 a 120 meses de edad, de nuevo ingreso al Inadej. Se determinaron variables hematológicas, yodo en orina y presencia de parásitos. Se utilizaron las pruebas Ji cuadrada y t de Student en variables no paramétricas y paramétricas. Resultados. Hubo más anemia (20 vs 7.4% p=0.007 y deficiencia de hierro (60.9 vs 44.4% p=0.02 en prescolares que en escolares. El 29% presentaron deficiencia de yodo (10.5% moderada o grave y 47.2% parasitosis. Predominaron G. lamblia y E. histolytica. Bajo salario, sexo masculino y no tener seguridad social se asociaron con parasitosis. Conclusiones. La elevada prevalencia de deficiencia de hierro, yodo y parasitosis obliga al sector salud estatal a ejecutar medidas eficaces para abatir estas enfermedades prevenibles.

Evaluación de anemia ferropénica en la primera infancia del Municipio de Sonsón-Antioquia, 2007

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Tulia Isabel Castillo Salgado

2014-12-01

Full Text Available Objetivo: Determinar la prevalencia de anemia por deficiencia de hierro en niños de la primera infancia del municipio de Sonsón – Antioquia, en el año 2007. Metodología: Se realizó un estudio descriptivo transversal en 391 niños de 0 a 84 meses de edad del Municipio de Sonsón, Antioquia. Se estudiaron los parámetros de hemoglobina y ferritina sérica utilizando puntos de corte de la Organización Mundial de la Salud (OMS. Se calcularon las medidas de frecuencia y de resumen y los intervalos de confianza para proporciones y las pruebas de estadística paramétrica y no paramétrica. Resultados: La prevalencia de anemia ferropénica fue de 4,3% y la media de ferritina sérica y de hemoglobina para la población del estudio fue de 29,9 ng/mL y 12,6 g/dL respectivamente. Adicionalmente se halló significancia estadística de la prevalencia de anemia ferropénica por grupo de edad (p<0,0001; pero no se encontró significancia estadística de la  prevalencia de anemia con el sexo (p= 1,0000.  Conclusión: La prevalencia de anemia ferropénica en los niños de la primera infancia del Municipio de Sonsón fue baja de acuerdo con los parámetros de hemoglobina y ferritina sérica establecidos por la OMS, hay variación de la anemia ferropénica por grupo de edad pero no por sexo.

Anemia hipocrómica y microcitaria por insuficiencia de aporte inicial (Congénita

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P. J. Sarmiento

1941-07-01

Full Text Available Todas las anemias hipocrómicas y microcitarias están caracterízadas por un síndrome hematológico común: a Son anemias simples, bilirrubinemia normal o baja: b Hipocromas, valor globular inferior a la unidad (o si se prefiere menor de 30 microgramos predominio de los microcitos, raros los macrocitos, escasa policromatofilia, poco numerosos los reticulocitos; c Son anemias hiperplásticas con hiperma-duración-mieloide; d Son anemias que mejoran con hierro.

Deficiencia de zinc y sus implicaciones funcionales Zinc deficiency and its functional implications

OpenAIRE

JORGE L ROSADO

1998-01-01

El presente trabajo tiene por objeto revisar los aspectos teóricos y los estudios realizados en México que sugieren la existencia de la deficiencia moderada de zinc en niños de población rural, así como algunas de las consecuencias de dicha deficiencia en la salud. El zinc es un nutrimento indispensable para el organismo de los humanos y juega un papel importante en una serie de procesos metabólicos: participa en el sitio catalítico de varios sistemas enzimáticos; participa como ion estructur...

Prevalencia de la anemia ferropénica en mujeres embarazadas

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Francisca Rosa Sánchez Salazar

2001-02-01

Full Text Available Con el objetivo de identificar la prevalencia de la anemia por deficiencia de hierro, se estudió en la consulta de nutrición del Hospital Docente Ginecoobstétrico "Eusebio Hernández", desde enero de 1993 a diciembre de 1999 a 11 904 gestantes; de ellas 5 169 eran portadoras de anemia ferropénica. La prevalencia alcanzó el 43,1 % y el grupo de edad más vulnerable fue el de 20 a 24 años. Las gestantes con bajo peso preconcepcional y las comprendidas entre las 14 y 23 semanas de gestación fueron las más afectadas. La anemia de mayor prevalencia fue la leve, y representó el 75,8 %, mientras que las variables maternas más involucradas fueron: los deficientes hábitos alimentarios, la hiperemesis gravídica y los antecedentes de 3 o más abortos. Este estudio evidenció la magnitud y el grado de severidad de la anemia ferropénica en las gestantes atendidasIn order to identify the prevalence of iron-deficiency anemia, 11 904 pregnant women were studied at the nutrition consulting room of "Eusebio Hernández" Gynecoobstetric Hospital from January, 1993, to December, 1999. 5 169 of them were carriers of iron-deficiency anemia. There was a prevalence of 43,1 % and the age group 20-24 was the most vulnerable. The expectants with low preconceptional weight as well as those between the 14th and the 23rd week were the most affected. Mild anemia prevailed and accounted for 75,8 %, whereas the most involved maternal variables were: deficient food habits, hyperemesis gravidis and history of 3 or more abortions. This study proved the magnitude and degree of iron-deficiency anemia of the pregnant women that were attended

Asociación entre la ingesta de nutrientes hematopoyéticos y el origen nutricional de la anemia en mujeres en edad fértil en Colombia Association between hematopoietic nutrient intake and the origin of nutritional anemia in women of childbearing age in Colombia

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Luz Mariela Manjarrés

2012-01-01

Full Text Available OBJETIVO: Comparar el origen de la anemia nutricional según las variables sociodemográficas y analizar su asociación con la deficiencia en la ingesta de nutrientes hematopoyéticos. MÉTODOS: Se utilizó la base de datos de la Encuesta Nacional de la Situación Nutricional de Colombia, 2005. Los datos se obtuvieron por muestreo complejo representativo de la población y se procesaron con el programa SPSS, v.15. Se seleccionaron mujeres en edad fértil con anemia y se clasificaron en dos grupos según la ferritina sérica. Se determinó la ingesta usual de nutrientes hematopoyéticos y el riesgo de deficiencia. Se compararon las proporciones de los tipos de anemia según las variables sociodemográficas utilizando la prueba F de Rao-Scott de segundo orden (P OBJECTIVES: Compare the nutritional origin of anemia by sociodemographic variables and analyze its association with deficient hematopoietic nutrient intake. METHODS: The database of Colombia's 2005 National Survey of Nutritional Status was used. The data were obtained through complex representative sampling of the population and processed using SPSS v.15. Anemic women of childbearing age were selected and divided into two groups according to serum ferritin levels. Their customary hematopoietic nutrient intake and risk of deficiency were determined. The proportions of anemia types were compared by sociodemographic variables using the F-distribution, the Rao-Scott second order correction (P < 0.05. The association between the origin of the anemia and classification of the nutrient was analyzed using the odds ratio (OR. RESULTS: Sample: 595 women. Non-hypoferric anemia (67.2% predominated, with no statistical difference by sociodemographic variable, except in the Pacific region (hypoferric anemia, 52.1%. The prevalence of deficiency in the customary intake of hematopoietic nutrients was high. There was no significant association between the deficit in consumption and the origin of the anemia

Prevalencia de deficiencia de vitamina a y anemia en niños menores de cinco años de Perú

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Jaime Pajuelo

Full Text Available Objetivos. Determinar la prevalencia de deficiencia de vitamina A (DVA y anemia nutricional (AN, en menores de cinco años en Perú. Materiales y métodos. Estudio transversal con muestreo probabilístico, estratificado y multietápico realizado entre noviembre de 2007 y abril de 2010. Se incluyó 2736 niños para AN y 1465 para DVA. Se definió AN a valores de Hb <11 g/dL. La DVA fue identificada por retinol sérico con valores < 20 µg/dL. Se estudiaron variables sociodemográficas relacionadas con el niño y la madre, además de su participación en programas de control de crecimiento y desarrollo, programa integral nutrición y suplementación con hierro y vitamina A. Se realizó el análisis para muestras complejas, se calculó estadísticas descriptivas y de regresión logística con un IC del 95% y un nivel de significación de p<0,05. Resultados. La prevalencia de DVA fue de 11,7% (IC 95%: 9,4-14,4, las prevalencias más altas fueron en niños menores de cinco meses (44,6%, y que viven en áreas rurales (19,5%. La prevalencia de AN fue de 33% (IC 95%: 29,9-36,1, siendo mayor en los niños menores de 11 meses (68,2% e hijos de madres con 13 a 19 años de edad (55,4%. Conclusiones. La DVA es un problema de salud pública que se mantiene, siendo los más afectados los niños que viven en las áreas rurales y en la selva. La prevalencia de AN muestra una ligera mejora. Es necesario mejorar la eficiencia e impacto de los programas de suplementación con vitamina A y hierro

Efecto de la anemia en el desarrollo infantil: consecuencias a largo plazo

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Zavaleta, Nelly; Centro Nacional de Alimentación y Nutrición, Instituto Nacional de Salud. Lima, Perú. Médico cirujano, master science en Nutrición; Astete-Robilliard, Laura; Centro Nacional de Alimentación y Nutrición, Instituto Nacional de Salud. Lima, Perú. Escuela de Nutrición, Universidad Peruana de Ciencias Aplicadas. Lima, Perú. nutricionista, magíster en Nutrición Pública

2017-01-01

La anemia en niños menores de tres años es un problema de salud pública en el Perú y el mundo. Se estima que la causa principal de la anemia, aunque no la única, es la deficiencia de hierro. Existen muchos estudios y revisiones sobre cómo esta carencia en los infantes impacta negativamente en el desarrollo psicomotor y, a pesar de corregirse la anemia, los niños con este antecedente presentan, a largo plazo, un menor desempeño en las áreas cognitiva, social y emocional. Estos hallazgos se des...

Diseño de un sistema para alertar riesgo en el déficit de micronutrientes

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Karanik, Marcelo J.; Suénaga, Roberto; Favret, Fabián; Eckert, Karina; Barreyro, María Eugenia

2013-01-01

Hoy en día vivimos en una sociedad globalizada, donde los factores que determinan lo que se ingiere, está muy influenciado por las consecuencias sociales y culturales de los hábitos alimentarios. Esto a su vez, produce deficiencias nutricionales por exceso o déficit de micronutrientes como vitaminas y minerales. Las deficiencias más comunes y seberas, son la de hierro y calcio, que pueden causar enfermedades como la anemia y osteoporosis. Por lo que es de suma importancia para la salud ...

Evaluación de anemia ferropénica en la primera infancia del Municipio de Sonsón-Antioquia, 2007

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Castillo Salgado, Tulia Isabel; Pérez Escobar, Rocío

2014-01-01

Objetivo: Determinar la prevalencia de anemia por deficiencia de hierro en niños de la primera infancia del municipio de Sonsón – Antioquia, en el año 2007. Metodología: Se realizó un estudio descriptivo transversal en 391 niños de 0 a 84 meses de edad del Municipio de Sonsón, Antioquia. Se estudiaron los parámetros de hemoglobina y ferritina sérica utilizando puntos de corte de la Organización Mundial de la Salud (OMS). Se calcularon las medidas de frecuencia y de resumen y los intervalos de...

Prevalencia de anemia en gestantes, Hospital Regional de Pucallpa, Perú

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Becerra César

1998-01-01

Full Text Available Las encuestas demográficas de salud y población del Perú indican que las tasas globales de fecundidad, la proporción de adolescentes embarazadas y la mortalidad maternoinfantil son más altas en la selva que en otras zonas del país. Las parasitosis intestinales endémicas agravan el riesgo de anemia ya generalmente presente en las embarazadas por deficiencias de hierro, ácido fólico y otros nutrientes. En muchos países latinoamericanos, esa es la complicación más frecuente del embarazo y está asociada con partos pretérmino, bajo peso al nacer y mortalidad perinatal. Los estudios realizados sobre este tema en la selva peruana son escasos y no se dispone de estimaciones confiables de la prevalencia de anemia durante la gestación. Los autores se propusieron determinar la prevalencia de anemia en mujeres gestantes que acudían al Hospital Regional de Pucallpa, en la selva del Perú, entre enero de 1993 y junio de 1995. El estudio de corte transversal se basó en los registros de control prenatal y de parto de 1 015 embarazadas y permitió estudiar la asociación entre la prevalencia de anemia y variables como edad cronológica, escolaridad, número de gestaciones previas y peso de la madre al inicio del embarazo. También se compararon los valores de la hemoglobina materna con el peso de los recién nacidos. La prevalencia de anemia en la población de gestantes fue de 70,1%, valor que no se modificó por efecto de la edad materna, la escolaridad ni el intervalo intergenésico. La prevalencia de anemia se asoció directamente con el número de gestaciones e inversamente con la ganancia de peso durante el embarazo. La tasa de mortalidad perinatal fue de 37,7 por 1 000 nacidos. Ni esta tasa ni el peso de los recién nacidos resultaron asociados con el grado de anemia de la madre. El análisis de regresión multivariado muestra que el peso de la madre al inicio de la gestación (P = 0,0001, el peso ganado durante la gestación (P = 0

Prevalência da anemia em crianças avaliada pela palidez palmar e exame laboratorial: implicações para enfermagem Sentimientos de mujeres-madres delante de la cirugía neonatal en las malformaciones congénitas Prevalence of anemia in children assessed by clinical method known as "palmar pallor" and the laboratory exam: implications for nursing

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Ethel Bastos da Silva

2011-09-01

Full Text Available Buscou-se analisar a prevalência de anemia ferropriva em crianças e comparar os dados obtidos pelo método clínico "palidez palmar" e exame laboratorial em uma Estratégia de Saúde da Família no município de Panambi/RS. Pesquisa exploratória/descritiva, quantitativa, realizada de março a junho de 2009. Foram sujeitos 41 crianças de 2 meses a 5 anos. Os dados foram analisados pela estatística descritiva. Das crianças, 51,2% eram do sexo masculino; 41,46% estavam na faixa etária de 0 a 12 meses; 53,6% das famílias situavam-se no nível social D e 43,9% dos chefes de família tinham o Ensino Fundamental completo ou o Ensino Médio incompleto. Pela palidez palmar, a prevalência de anemia foi de 51,2% e pelo exame laboratorial, de 58,53%. O estudo mostra que a palidez palmar e o exame laboratorial, quando usados juntos, fornecem um diagnóstico mais preciso da anemia ferropriva, podendo ser inseridos na prática assistencial da enfermagem na ESF.Se intenta analizar la prevalencia de anemia por deficiencia de fierro en niños y comparar el método clínico "palidez palmar" y el examen de laboratorio en una Estrategia de Salud de la Familia en la municipalidad de Panambi-RS. La pesquisa exploratoria, descriptiva y cuantitativa fue realizada de marzo hasta junio de 2009. Los sujetos fueron 41 niños de 2 meses a 5 años de edad. Los datos fueron analizados por la estadística descriptiva. Del total de niños, 51,2% eran del sexo masculino; 41,46% estaban en la franja etaria de 0 a 12 meses; 53,6% de las familias se sitúan en el nivel social D y 43,9% de los jefes de familia tienen la Enseñanza Fundamental Completa o la Enseñanza Media Incompleta. Por la palidez palmar, la prevalencia de anemia fue de 51,2% y por el examen de laboratorio, de 58,53%. El estudio muestra que la palidez palmar y el examen de laboratorio, cuando usados juntos, proveen un diagnóstico más preciso de la anemia por deficiencia de fierro, pudiendo ser inserido

Tratamento da anemia ferropriva com ferro por via oral

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Rodolfo D. Cançado

Full Text Available A anemia ferropriva permanece como uma das deficiências nutricionais mais frequentes e importantes no mundo. O tratamento com ferro deve ser iniciado preferencialmente por via oral e a investigação apropriada de sua causa é obrigatória. Os autores discutem os compostos com ferro atualmente disponíveis, o perfil de eficácia, segurança e tolerabilidade desses medicamentos, e o plano terapêutico mais adequado possível para o sucesso no tratamento dessa doença tão comum e importante.

Micronutrient deficiencies in the English-speaking Caribbean and in Guyana

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1998-01-01

Full Text Available Tres estudios recientes analizaron el grado de deficiencia de vitamina A, betacarotenos y hierro en Jamaica, Antigua y Barbuda, Dominica, San Vicente y las Granadinas y Guyana. Todos los estudios fueron efectuados por el Instituto Caribeño de Alimentación y Nutrición, o en colaboración con él. En todas las encuestas, que fueron similares en su estructura y resultados, se recolectaron muestras de sangre con el fin de determinar las deficiencias de micronutrientes. También se aplicaron cuestionarios para recoger información sobre los patrones de alimentación. Los principales grupos estudiados fueron los niños pequeños, los escolares y las mujeres embarazadas. La anemia por deficiencia de hierro fue la deficiencia de micronutrientes más común de las que se encontraron en los tres estudios. Aunque se hallaron pocos casos de deficiencia de vitamina A grave, fueron más comunes las deficiencias marginales. En los tres estudios se hicieron recomendaciones similares para hacer frente a las deficiencias detectadas en los diversos países. Es menester que los gobiernos y otras agencias sigan promoviendo la disponibilidad y el consumo de alimentos ricos en vitamina A y caroteno. Los programas contra la anemia deben dirigirse específicamente hacia los niños de 1 a 4 años de edad y las mujeres embarazadas.

Deficiencia de zinc y sus implicaciones funcionales Zinc deficiency and its functional implications

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JORGE L ROSADO

1998-03-01

Full Text Available El presente trabajo tiene por objeto revisar los aspectos teóricos y los estudios realizados en México que sugieren la existencia de la deficiencia moderada de zinc en niños de población rural, así como algunas de las consecuencias de dicha deficiencia en la salud. El zinc es un nutrimento indispensable para el organismo de los humanos y juega un papel importante en una serie de procesos metabólicos: participa en el sitio catalítico de varios sistemas enzimáticos; participa como ion estructural en membranas biológicas, y guarda una estrecha relación con la síntesis de proteínas, entre otras cosas. Es por esto que la deficiencia de zinc está asociada con consecuencias importantes en la salud y la funcionalidad de los individuos, especialmente durante las primeras etapas de la vida. De relevancia para México es la existencia de una deficiencia moderada de zinc en los niños y las consecuencias que ésta pueda tener en la salud de los mismos. Los estudios realizados sugieren que la deficiencia moderada de zinc se presenta asociada con la ingestión de dietas basadas en alimentos de origen vegetal, las cuales contienen cantidades importantes de inhibidores de la absorción de zinc. Este tipo de dietas se consume habitualmente en las zonas rurales y en la población marginal de las ciudades en el país. Entre las consecuencias más importantes de esta deficiencia se encontró un aumento en la presencia de enfermedades infecciosas, especialmente de diarrea, y posibles alteraciones en el desarrollo de la capacidad cognoscitiva.The purpose of this article is to review theoretical aspects and research performed in Mexico suggesting the existence of marginal zinc deficiency in rural children and its consequences on health. Zinc is an indispensable nutrient for humans since it plays an important role in several metabolic pathways: it participates in the catalytic site of several enzymes, as a structural ion of biological membranes and is

Deficiencia combinada de proteínas c y s

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Yaneth Zamora-González

Full Text Available Las trombofilias son un grupo de enfermedades que favorecen la formación de trombosis, tanto arteriales como venosas, que han sido asociadas con diferentes complicaciones durante el embarazo, como: aborto recurrente, preclampsia, crecimiento intrauterino retardado y muerte fetal intraútero, entre otras. La deficiencia congénita o adquirida de proteínas de la coagulación, como las proteínas C y S, se asocia con eventos trombóticos antes de los 30 o 40 años. La trombosis venosa profunda es considerada la manifestación clínica más frecuente, aunque también puede verse asociada con enfermedad cerebro vascular, pérdidas recurrentes de embarazos y otros estados isquémicos. En la actualidad, las enfermedades trombóticas constituyen una de las primeras causas de fallecimiento en el mundo; la morbimortalidad anual por trombosis, ya sea arterial o venosa, es de aproximadamente dos millones de personas. Presentamos un caso con antecedentes de pérdidas recurrentes de embarazos y trombosis venosa profunda en miembros inferiores con deficiencia combinada de proteínas C y S.

Incidencia y mortalidad por anemia en pacientes gravemente enfermos Incidence and mortality due to anemia in acutely ill patients

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Maicelys Ramírez Zaldívar

2012-09-01

Full Text Available Introducción: la anemia es una de las enfermedades más conocidas y evaluadas en la práctica médica diaria. Objetivo: determinar la morbilidad y mortalidad de pacientes graves con anemia. Métodos: se realizó un estudio prospectivo de 118 pacientes ingresados en la Unidad de Terapia Intensiva del Hospital General Universitario "Vladimir Ilich Lenin" de Holguín, desde agosto hasta diciembre de 2010. Las variables discretas fueron comparadas mediante el test de £i al cuadrado y el de Fisher, y las continuas, por medio de las pruebas de T-Student y Mann-Whitney (la hemoglobina media, para á=0,05. Resultados: la anemia afectó 79,6 % de los integrantes de la serie y aumentó evolutivamente, con el consecuente empeoramiento de estos, de los cuales fallecieron 34,0 %, quienes tenían mayor edad (p=0,0004, necesitaron más transfusiones sanguíneas (p=0,005 y presentaron el trastorno de la hemoglobina más tardíamente (5,1 días. De los pacientes con anemia grave (hemoglobina:0,05. Conclusiones: la anemia en los pacientes graves se relacionó con una mayor mortalidad, estadía, necesidad de transfusiones de glóbulos rojos y causas médicas (neurológicas, en tanto, la edad avanzada y la gravedad de la anemia de aparición tardía se asociaron fundamentalmente a la mortalidad.Introduction: anemia is one of the well-known and evaluated diseases in the daily medical practice. Objective: to determine the morbidity and mortality of acutely ill patients with anemia. Methods: a prospective study of 118 patients admitted in the Intensive Therapy Unit of "Vladimir Ilich Lenin" General University Hospital in Holguín was carried out from August to December, 2010. Discrete variables were compared by means of the X² and Fisher tests, and the continuous variables, by means of the T-Student and Mann-Whitney tests (the mean hemoglobin, for á =0.05. Results: anemia affected 79.6% of the members of the series and it increased progressively, with the

Efecto de las deficiencias nutricionales en la distribución de la materia seca en plantas de vivero de curuba (Passiflora mollissima Bailey

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Cabezas Marco

2008-08-01

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Para confirmar el efecto que tienen las deficiencias de nutrientes minerales mayores en la asignación de la materia seca en órganos vegetativos de Passiflora mollissima, se realizó un experimento en condiciones de vivero, mediante la técnica de deficiencia inducida por elemento faltante. Se pudo establecer que las deficiencias de N y K reducen en alta proporción el área foliar y la masa de la planta, mientras que las deficiencias de P afectan el patrón de distribución de la biomasa, al favorecer la mayor acumulación en la raíz. En general, las deficiencias de macronutrientes afectan de forma drástica la distribución de la materia seca en los órganos vegetativos de la planta y producen síntomas específicos que pueden servir como indicadores del estado nutricional en condiciones de campo.

Fatores de risco para anemia por deficiência de ferro em crianças e adolescentes parasitados por helmintos intestinais Risk factors for iron-deficiency anemia in children and adolescents with intestinal helminthic infections

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Luciara L. Brito

2003-12-01

Full Text Available OBJETIVO: Investigar os fatores de risco para anemia por deficiência de ferro em crianças e adolescentes (7 a 17 anos infectados por helmintos. MÉTODOS: Foi realizado um estudo transversal com 1709 crianças e adolescentes residentes na cidade de Jequié, Estado da Bahia, Brasil, que apresentavam infecção leve ou moderada por Schistosoma mansoni, Ascaris lumbricoides, Trichuris trichiura e ancilostomídeos. Foram obtidos dados sobre níveis de hemoglobina (hemoglobinômetro portátil, consumo alimentar (inquérito recordatório de 24 horas, infecção parasitária (método Kato-Katz, condições ambientais e domiciliares, renda e escolaridade dos responsáveis. Os fatores de risco para anemia na população foram estudados com base em um modelo hierárquico de causalidade. RESULTADOS: A prevalência de infecção por T. trichiura, A. lumbricoides, S. mansoni e ancilostomídeos foi de 74,8, 63,0, 55,5 e 15,7%, respectivamente. Constatou-se que 32,2% das crianças e adolescentes eram anêmicos. Depois do ajuste para variáveis de confusão, os resultados da análise multivariada mostraram que a renda familiar per capita abaixo de um quarto do salário mínimo (27 dólares, o sexo masculino, a faixa etária de 7 a 9 anos e a ingestão inadequada de ferro biodisponível foram significativamente associados à anemia. CONCLUSÕES: As ações para controle da anemia no grupo de maior risco, conforme identificado no presente estudo, devem visar o aumento do consumo de alimentos ricos em ferro e da biodisponibilidade do ferro ingerido, bem como a melhoria das condições sócio-ambientais.OBJECTIVE: To investigate risk factors for iron-deficiency anemia in children and adolescents (7 to 17 years of age with intestinal helminthic infections. METHODS: A cross-sectional study was carried out with 1 709 children and adolescents living in Jequié, a town in the state of Bahia, Brazil, who had mild to moderate infection by Schistosoma mansoni, Ascaris

Pancitopenia por anemia de Fanconi: presentación de un caso clínico.

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Miguel Zúñiga

2010-08-01

Full Text Available La anemia de Fanconi es una patología genética caracterizada por una alteración en la reparación del ADN que se expresa con alteraciones físicas y hematológicas. Es una enfermedad congénita rara y corresponde a la primera causa de anemia aplásica en la infancia. Tiene un curso desfavorable tanto por el deterioro de sus parámetros sanguíneos, así como también por el riesgo aumentado de malignización hematológica. Su único tratamiento curativo es el trasplante de médula ósea. Se presenta el caso de un niño de 3 años, hijo de padres judíos, portador de malformaciones mayores y menores, que presentó un cuadro infeccioso por Mycoplasma pneumoniae que evolucionó a una pancitopenia severa. En el  estudio del caso se buscaron etiologías  que abarcaron desde las infecciosas e inmunológicas hasta  las que involucraban a la medula ósea Una vez que los exámenes realizados descartaron patologías linfoproliferativas, la clínica y la persistencia del cuadro orientaron a buscar alguna condición genética que explicara esta situación.

DIAGNÓSTICO Y TRATAMIENTO DE LA DEFICIENCIA DE VITAMINA D

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Miranda C, Daisy; Leiva B, Laura; León S, José Pablo; de la Maza C, Ma Pía

2009-01-01

El estado nutrícional de vitamina D ha cobrado importancia en los últimos años debido a que su deficiencia es altamente prevalente, y además por sus conocidos efectos en el metabolismo óseo, participa en la diferenciación y proliferación celular, función muscular y equilibrio, entre otros. La molécula activa es la 1,25(OH)2D, pero se recomienda medir niveles séricos de 25 OH vitamina D total (es decir la suma de ergocalciferol o vitamina D2 y colecalciferol o vitamina D3), como reflejo del st...

Estudio poblacional de prevalencia de anemia ferropénica en La Plata y sus factores condicionantes

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Marín, Gustavo Horacio

2006-01-01

La anemia es una de las mayores causales de muerte en la población mundial, y constituye el problema nutricional más grave en el mundo. La anemia y la deficiencia de hierro afectan a aproximadamente mil ochocientos millones de personas. Entre los grupos más afectados figuran las mujeres en edad fértil debido a las pérdidas de sangre en las menstruaciones; las embarazadas, ya que tienen un aumento en las demandas de sangre que determina que los requerimientos de hierro de su organismo no pueda...

Trastornos Asociados a la Deficiencia de Yodo. Vigilancia permanente es deficitaria en zonas vulnerables

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Hernando Vargas-Uricoechea

2012-04-01

Full Text Available Los Desórdenes por Deficiencia de Yodo (DDY son uno de los mayores problemas en salud pública en el mundo actual, en especial en niños y embarazadas. Estos trastornos truncan el desarrollo socioeconómico en aquellas zonas que los padecen; las poblaciones que viven en zonas yodo-deficientes siempre van a estar expuestas a sufrir las consecuencias originadas por esta deficiencia, en especial el aumento en la mortalidad perinatal, retardo mental, alteraciones en la síntesis de hormonas tiroideas, hipotiroidismo, hipertiroidismo y bocio. La mejor forma de evaluar los DDY es por medio de la yoduria y la mejor estrategia para reducir la prevalencia de estos desórdenes en la población es a través de la yodación universal de la sal. Para actualizar el conocimiento de esta problemática –tanto en el mundo como en Colombia- se realizó una revisión sistemática de la literatura médica expuesta en las bases de datos de MEDLINE y de LILACS. En total, la búsqueda arrojó la presencia de 723 artículos, la revisión de sus resúmenes permitió escoger inicialmente 114 artículos, de los cuales se decidió incluir en la revisión a 60 de ellos. Se encontró que en Colombia el diagnóstico de DDI es subvalorado, desconociéndose la problemática actual y el estado del yodo poblacional, por lo que es necesario realizar estos estudios, ya que es evidente el abandono político de este problema prevenible, predecible y tratable.

Síntomas de deficiencia de macronutrientes y boro en plantas de uchuva (Physalis peruviana L.

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Martínez Fabio Ernesto

2009-08-01

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El desconocimiento de los signos y síntomas visibles de las deficiencias nutricionales no permite establecer oportunos correctivos para manejar plantas con suficiente vigor, producción y calidad de los frutos. Plantas de uchuva ecotipo Colombia, propagadas por semilla, se sembraron en sustrato de arena cuarcítica en materas de plástico (25 L, y se mantuvieron durante 135 días en condiciones de invernadero de plástico en Bogotá. Las deficiencias nutricionales se indujeron a través de soluciones nutritivas, usando el método del elemento faltante y empleando un diseño completamente al azar con ocho tratamientos y cinco repeticiones, a saber: T0. testigo con fertilización completa; T1. fertilización completa –N; T2. –P; T3. –K; T4. –Ca; T5. –Mg; T6. –B, y T7. agua potable únicamente. Solamente en el caso del nitrógeno se aplicó 15% del N de la fertilización completa. Quincenalmente se efectuó una descripción visual y se llevó un registro fotográfico de los síntomas manifestados. Las plantas con deficiencias de N, K y B presentaron los síntomas más severos, generando efectos negativos sobre la arquitectura y el deficiente porte de las plantas, además de causar una seria afección sobre el tejido vegetal. Las plantas deficientes en B tomaron una forma de roseta, típico síntoma hipoplástico. Las uchuvas que sufrieron deficiencias de P, Ca, Mg presentaron distorsiones en el color del follaje, observándose para la deficiencia de P, una coloración púrpura tanto en hojas de la zona reproductiva de la planta como en las del tallo principal. Las deficiencias de Mg y Ca, respectivamente, indujeron clorosis foliar intervenal y coloraciones anaranjadas.

PREVALENCIA DE LA DEFICIENCIA DE HIERRO EN DONANTES DE SANGRE. REVISIÓN BIBLIOGRÁFICA DEL PERÍODO 2001- 2011

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Carmen Yulieth Mantilla-Gutiérrez

2012-01-01

Full Text Available Fundamentos: La donación de sangre se asocia con disminución de las reservas de hierro de los donantes, lo que puede afectar el desarrollo de sus funciones fisiológicas y al estado general de salud. Estudios previos reportan una gran divergencia en la prevalencia de deficiencia de hierro en dicha población (1% a 62%. El objetivo del trabajo es determinar la prevalencia de deficiencia de hierro en donantes de sangre a partir de una revisión sistemática de la literatura. Métodos: Búsqueda exhaustiva y reproducible de la literatura en 7 bases de datos con base en un protocolo de búsqueda de estudios en 4 idiomas y publicados entre el 2001 y el 2011 con criterios de inclusión, exclusión y extracción de información. El análisis se realizó con base en el cálculo de la prevalencia global y específica por sexo y número de donaciones, con sus respectivos intervalos de confianza, utilizando los programas Excel y Epidat 3.0. Resultados: Se obtuvo una población total de 16.979 donantes, 5.096 de repetición, con una proporción de hombres del 59%. Se halló una prevalencia de deficiencia de hierro del 13% (IC 95% 12,4-13,4, con una rango entre 1% y 62%, siendo estadísticamente significativa la mayor frecuencia en mujeres (19,56% IC 95%: 18,59 - 20,53 y donantes repetidores (20,36% IC 95%: 19,25 - 21,48. Conclusión: Se obtuvo una prevalencia de deficiencia de hierro en donantes de sangre por encima de grupos de mayor riesgo como los niños, siendo mayor en donantes del sexo femenino y de repetición.

Asma y deficiencia de subclases de IgG Asthma and IgG subclases deficiency

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Lucía Santamaría Ortiz

1995-04-01

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Se estudiaron 45 pacientes asmáticos adultos de difícil manejo, de más de 5 años de evolución, 37 de ellos esteroide dependientes y 8 no dependientes, con asma alérgica o intrínseca y algunos con Infecciones respiratorias recurrentes de predominio viral. Por nefelometría se midieron los niveles séricos de las IgsG, M y A, y por ELISA se determinó la IgE total. Se encontraron 4 pacientes con deficiencia de IgG total, en el grupo de los esteroide dependientes. Mediante ELISA tipo sandwich y con anticuerpos monoclonales específicos para las sub clases de IgG se investigaron los niveles sé ricos de IgG1, 2, 3 y 4. En el 55.6% de los enfermos se encontraron una O más deficiencias de sub clases. No hubo diferencias significativas entre los grupos esteroide y no esteroide dependientes, ni entre los asmáticos alérgicos e intrínsecos, ni entre los con infección recurrente o sin ella. predominó la deficiencia de IgG1; en total el 46.7% de los pacientes tenían deficiencia aislada o combinada de IgG1, el 31.1% de IgG2, el 24.4% de IgG3 y el 17.8% de Igd4. La alta incidencia de deficiencia de sub clases podría deberse a la acción de los esteroides o a una alteración en la regulación de la síntesis de Igs producida por un defecto Inmune primario. Esta deficiencia sería la responsable del comportamiento agresivo de la enfermedad.

We studied 45 adult asthmatic patients with difficult to care disease and who had more than five years of evolution; they suffered from elther allergic or intrinsic asthma and some had experienced recurrent respiratory tract infections. predominantly of viral etiology. Serum levels of IgA, IgG and IgM were measured by nephelometry and total lgE was determined by an Enzyme-Linked immunosorbent Assay (ELISA. Total lg

El programa de suplementación con "Prenatal" para la prevención de la anemia en el embarazo

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Magaly Padrón Herrera

1998-06-01

Full Text Available La anemia por deficiencia de hierro es el más frecuente problema nutricional en nuestro país y en especial en la población de gestantes. Para su prevención y control se utiliza la suplementación con preparados farmacéuticos como una forma práctica y efectiva para aliviar el problema. Para este fin se utiliza en la atención primaria el suplemento prenatal especialmente diseñado para el Programa de Atención Maternoinfantil. En el presente trabajo se exponen conocimientos esenciales del problema, los aspectos básicos para lograr una real efectividad en la acción preventiva y la función que debe desempeñar el médico de la familia en el programa de suplementación con prenatal para la prevención de la anemia en el embarazoIron-deficiency anemia is the most frequent nutritional problem in our country, and specially among pregnant women. For its prevention and control it is used the supplementation with pharmaceutical preparations as a practical and effective way to alleviate the situation. To this end, the prenatal supplement specially designed by the Program of Maternal and Child Care is used at the primary health care level. The essential knowledge of the problem, the basic aspects to achieve a real effectiveness in the preventive action, and the role the family physician should played in the supplementation program with prenatal for the prevention of anemia during pregnancy are approached in this paper

Biomarcadores del metabolismo y nutrición de hierro

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Sermini, Carmen Gloria; Laboratorio de Micronutrientes, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile. Nutricionista; Acevedo, María José; Laboratorio de Micronutrientes, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile. Nutricionista; Arredondo, Miguel; Laboratorio de Micronutrientes, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile. Msc; Phd

2017-01-01

RESUMEN La anemia por deficiencia de hierro continúa siendo la deficiencia nutricional más abundante en el mundo, y son los lactantes, preescolares, mujeres en edad fértil y embarazadas los grupos de mayor susceptibilidad. Debido a esto es que se hace necesario el conocer los mecanismos de regulación de captación, transporte y absorción del metal a nivel celular, principalmente a nivel del enterocito y, una vez que el hierro entra a la circulación, conocer cuáles son los biomarcadores que per...

Encuesta de ceguera y deficiencia visual evitable en Panamá

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Maritza López

2014-12-01

Full Text Available OBJETIVO: Determinar la prevalencia de ceguera y deficiencia visual en adultos de 50 años o más de Panamá, identificar sus principales causas y caracterizar la oferta de servicios de salud ocular. MÉTODOS: Estudio poblacional transversal mediante la metodología estándar de evaluación rápida de ceguera evitable. Se seleccionaron 50 personas de 50 años o más de cada uno de 84 conglomerados escogidos mediante muestreo aleatorio representativo de todo el país. Se evaluó la agudeza visual (AV mediante una cartilla de Snellen y el estado del cristalino y del polo posterior por oftalmoscopía directa. Se calculó la cobertura de cirugía de catarata y se evaluó su calidad, así como las causas de tener AV < 20/60 y las barreras para acceder al tratamiento quirúrgico. RESULTADOS: Se examinaron 4 125 personas (98,2% de la muestra calculada. La prevalencia de ceguera ajustada por la edad y el sexo fue de 3,0% (intervalo de confianza de 95%: 2,3-3,6. La principal causa de ceguera fue la catarata (66,4%, seguida del glaucoma (10,2%. La catarata (69,2% fue la principal causa de deficiencia visual (DV severa y los errores de refracción no corregidos fueron la principal causa de DV moderada (60,7%. La cobertura quirúrgica de catarata en personas fue de 76,3%. De todos los ojos operados de catarata, 58,0% logró una AV < 20/60 con la corrección disponible. CONCLUSIONES: La prevalencia de ceguera en Panamá se ubica en un nivel medio con respecto a la encontrada en otros países de la Región. Es posible disminuir este problema, ya que 76,2% de los casos de ceguera y 85,0% de los casos de DV severa corresponden a causas evitables.

Encuesta nacional de ceguera y deficiencia visual evitables en Honduras

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Doris Alvarado

2014-11-01

Full Text Available OBJETIVO: Determinar la prevalencia de ceguera y deficiencia visual en Honduras, sus causas y la respuesta que los servicios de salud están dando a la creciente demanda. MÉTODOS: Estudio poblacional transversal realizado entre junio y diciembre de 2013 mediante la metodología estándar de evaluación rápida de ceguera evitable. Se realizó un muestreo aleatorio en 63 conglomerados de 50 personas de 50 años o más, representativo de todo el país. Se evaluó la agudeza visual (AV mediante una cartilla de Snellen y el estado del cristalino y del polo posterior por oftalmoscopía directa. Se calculó la cobertura de cirugía de catarata y se evaluó su calidad, las causas de tener AV < 20/60 y las barreras para acceder al tratamiento quirúrgico. RESULTADOS: Se examinaron 2 999 personas (95,2% del total previsto. La prevalencia de ceguera fue de 1,9% (intervalo de confianza de 95%: 1,4-2,4% y 82,2% de esos casos era evitable. La catarata no operada fue la causa principal de ceguera (59,2%, seguida del glaucoma (21,1%. Los errores de refracción no corregidos fueron la principal causa de deficiencia visual, tanto severa (19,7% como moderada (58,6%. La cobertura de cirugía de catarata fue de 75,2%. De los ojos operados de catarata, 62,5% alcanzó una AV ≥ 20/60 con la corrección disponible. Las principales barreras para someterse a la cirugía de catarata fueron el costo (27,7% y la falta de disponibilidad o de acceso geográfico al tratamiento (24,6%. CONCLUSIONES: La prevalencia de ceguera y deficiencia visual en Honduras es similar a la de otros países latinoamericanos. Mejorar la capacidad resolutiva de los servicios oftalmológicos, especialmente de cirugía de catarata, desarrollar los servicios ópticos y la atención ocular incorporada en la atención primaria en salud, podrían resolver el 67% de los casos de ceguera.

Prevalencia de deficiencia de hierro y yodo, y parasitosis en niños de Arandas, Jalisco, México Prevalence of iron and iodine deficiency and parasitosis in children from Arandas, Jalisco, Mexico

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Edgar Manuel Vásquez-Garibay

2002-06-01

Full Text Available Objetivo. Estimar la prevalencia de deficiencia de hierro, yodo y parasitosis en niños que asisten al Instituto Alteño para el Desarrollo de Jalisco (Inadej, Arandas, Jalisco, México. Material y métodos. Estudio transversal efectuado entre 1997 y 1999 con 432 niños de 12 a 120 meses de edad, de nuevo ingreso al Inadej. Se determinaron variables hematológicas, yodo en orina y presencia de parásitos. Se utilizaron las pruebas Ji cuadrada y t de Student en variables no paramétricas y paramétricas. Resultados. Hubo más anemia (20 vs 7.4% p=0.007 y deficiencia de hierro (60.9 vs 44.4% p=0.02 en prescolares que en escolares. El 29% presentaron deficiencia de yodo (10.5% moderada o grave y 47.2% parasitosis. Predominaron G. lamblia y E. histolytica. Bajo salario, sexo masculino y no tener seguridad social se asociaron con parasitosis. Conclusiones. La elevada prevalencia de deficiencia de hierro, yodo y parasitosis obliga al sector salud estatal a ejecutar medidas eficaces para abatir estas enfermedades prevenibles.Objective. To estimate the prevalence of iron deficiency, iodine deficiency and parasitosis in children attending the Instituto Alteño para el Desarrollo de Jalisco ((Highlands Institute for Development of Jalisco State, INADEJ, Arandas, Jalisco, Mexico. Material and Methods. A cross-sectional study was conducted between 1997 and 1999, among 432 children aged 12 to 120 months attending the INADEJ. Measurements included hematological values, urine iodine concentration, and presence of parasites. Student's t test chi square tests were used for parametric and non-parametric analysis. Results. The prevalence figures of anemia (20 vs 7.4%, p=0.007 and iron deficiency (60.9 vs 44.4%, p=0.02 were higher in preschool than in school children. Iodine deficiency was found in 29% (10.5% moderate or severe and parasitosis in 47.2% of children, mainly E. histolytica (30.2% and G. lamblia (28.9%. Low income, male gender and lack of social

Uso de medicamentos por pessoas com deficiências em áreas do estado de São Paulo Uso de medicamentos por personas con deficiencias en áreas del Estado de Sao Paulo, Sureste de Brasil Use of medicines by persons with disabilities in São Paulo state areas, Southeastern Brazil

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Shamyr Sulyvan Castro

2010-08-01

Full Text Available OBJETIVO: Analisar o consumo de medicamentos e os principais grupos terapêuticos consumidos por pessoas com deficiências físicas, auditivas ou visuais. MÉTODOS: Estudo transversal em que foram analisados dados do Inquérito Multicêntrico de Saúde no Estado de São Paulo (ISA-SP em 2002 e do Inquérito de Saúde no Município de São Paulo (ISA-Capital, realizado em 2003. Os entrevistados que referiram deficiências foram estudados segundo as variáveis que compõem o banco de dados: área, sexo, renda, faixa etária, raça, consumo de medicamentos e tipos de medicamentos consumidos. RESULTADOS: A percentagem de consumo entre as pessoas com deficiência foi de: 62,8% entre os visuais; 60,2% entre os auditivos e 70,1% entre os físicos. As pessoas com deficiência física consumiram 20% mais medicamentos que os não-deficientes. Entre as pessoas com deficiência visual, os medicamentos mais consumidos foram os diuréticos, agentes do sistema renina-angiotensina e analgésicos. Pessoas com deficiência auditiva utilizaram mais analgésicos e agentes do sistema renina-angiotensina. Entre indivíduos com deficiência física, analgésicos, antitrombóticos e agentes do sistema renina-angiotensina foram os medicamentos mais consumidos. CONCLUSÕES: Houve maior consumo de medicamentos entre as pessoas com deficiências quando comparados com os não-deficientes, sendo os indivíduos com deficiência física os que mais consumiram fármacos, seguidos de deficientes visuais e auditivos.OBJETIVO: Analizar el consumo de medicamentos y los principales grupos terapéuticos consumidos por personas con deficiencias físicas, auditivas o visuales. MÉTODOS: Estudio transversal en que fueron analizados datos de la Pesquisa Multicentrica de Salud en el Estado de Sao Paulo (ISA-SP en 2002 y de la Pesquisa de Salud en el Municipio de Sao Paulo (ISA-Capital, realizado en 2003. Los entrevistados que refirieron deficiencias fueron estudiados según las variables

El deporte como causa de estrés oxidativo y hemólisis

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Javier F. Bonilla; Raúl Nárvaez; Lilian Chuaire

2005-01-01

Desde hace más de tres décadas se estableció que el ejercicio puede producir la anemia, una de las causas en la deficiencia de oxigenación a los tejidos. Sin embargo, esta relación preliminar realmente corresponde a un evento donde el plasma se diluye, razón por la cual no es una verdadera anemia, por lo que se acuñó el término “pseudoanemia del deportista”. La nueva información relaciona el ejercicio, de moderado a exhaustivo, con la pérdida de sangre a través de los sistemas gastrointestina...

Hookworm infection and anemia in adult women in rural Chiapas, Mexico Anemia e infección por Necator americanus en mujeres en Chiapas, México

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Paula E. Brentlinger

2003-04-01

Full Text Available OBJECTIVE: To describe associations between anemia and hookworm (Necator americanus infection in hospitalized women in rural Chiapas, Mexico. MATERIAL AND METHODS: We retrospectively reviewed the hospital records of 68 anemic women (defined as having a hemoglobin level OBJETIVO: Describir la asociación entre anemia severa e infección con Necator americanus en una población de mujeres hospitalizadas en el estado de Chiapas, México. MATERIAL Y MÉTODOS: En el registro de ingresos del año 1999 de un hospital rural en Altamirano, Chiapas, se identificaron a las pacientes con diagnósticos de egreso de anemia (definida como hemoglobina<10mg/dl y/o parasitosis intestinal. También se revisó el registro de transfusiones para identificar a las mujeres mayores de 14 años de edad que recibieron sangre. La revisión de expedientes y el análisis de datos se llevó a cabo en el año 2000. Las comparaciones de las características de las pacientes se hicieron con la prueba t de Student (para variables continuas y la prueba ji2 (para variables categóricas. La significancia estadística se estableció con un valor de p< 0.01. RESULTADOS: En las mujeres en quienes se realizó examen coproscópico, 50% tuvieron N. americanus. La presencia de N. americanus no excluyó la presencia de otro factor de riesgo para anemia, por ejemplo embarazo o hemorragia. Los niveles de hemoglobina de las mujeres infectadas con N. americanus fueron significativamente más bajos (promedio 4.1 g/dl que los de las demás mujeres anémicas (promedio 7.0 gm/dl, y la prevalencia de N. americanus en mujeres anémicas fue más alta (50.0% que en la población atendida por el hospital (1.9%. CONCLUSIONES: Aunque la prevalencia de infección con N. americanus no se considera alta en la población general mexicana, fue importante en las mujeres anémicas que se sometieron a coproscopía en nuestro estudio. Las mujeres anémicas ameritan coproscopía donde existe N. americanus, y pueden

Parasitosis intestinal y anemia en indígenas del resguardo Cañamomo-Lomaprieta, Colombia

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Jaiberth Antonio Cardona Arias

2014-07-01

Full Text Available Introducción: Las parasitosis intestinales son un problema de salud pública; producen deficiencias nutricionales y se asocian a determinantes demográficos y socioeconómicos. Objetivo: Determinar la prevalencia de parasitosis intestinal y anemia y su asociación con determinantes demográficos, socioeconómicos y sanitarios en indígenas. Materiales y Métodos: Estudio observacional analítico transversal con fuente de información primaria. Se estimaron medidas de resumen, pruebas de estadística paramétrica y no paramétrica, proporciones y regresión logística multivariante. Resultados: Prevalencia de anemia del 23% y parasitosis intestinal del 73%. Hubo asociación significativa de la anemia con la parasitosis intestinal y se identificó la forma de eliminación de excretas, el nivel educativo y los ingresos económicos como los principales factores de riesgo para la parasitosis intestinal en el grupo de estudio. Conclusión: Existe una elevada prevalencia de parasitosis intestinal que se asocia con la presencia de anemia y se atribuye a condiciones higiénico-sanitarias de las comunidades del resguardo indígena.

Parasitosis intestinal y anemia en indígenas del resguardo Cañamomo-Lomaprieta, Colombia

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Jaiberth Antonio Cardona Arias; Yennifer Rivera Palomino; Osman Mauricio Llanes Agudelo

2014-01-01

Introducción: Las parasitosis intestinales son un problema de salud pública; producen deficiencias nutricionales y se asocian a determinantes demográficos y socioeconómicos. Objetivo: Determinar la prevalencia de parasitosis intestinal y anemia y su asociación con determinantes demográficos, socioeconómicos y sanitarios en indígenas. Materiales y Métodos: Estudio observacional analítico transversal con fuente de información primaria. Se estimaron medidas de resumen, pruebas de estadística par...

Prevalence and risk factors of anemia in children

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Cristie Regine Klotz Zuffo

2016-07-01

Full Text Available Objective: To identify the prevalence and factors associated with anemia in children attending Municipal Early Childhood Education Day Care Center (Centros Municipais de Educação Infantil [CMEI] nurseries in Colombo-PR. Methods: Analytical, cross-sectional study with a representative sample of 334 children obtained by stratified cluster sampling, with random selection of 26 nurseries. Data collection was conducted through interviews with parents, assessment of iron intake by direct food weighing, and hemoglobin measurement using the finger-stick test. Bivariate association tests were performed followed by multiple logistic regression adjustment. Results: The prevalence of anemia was 34.7%. Factors associated with anemia were: maternal age younger than 28 years old (p = 0.03, male children (p = 0.02, children younger than 24 months (p = 0.01, and children who did not consume iron food sources (meat + beans + dark green leafy vegetables (p = 0.02. There was no association between anemia and iron food intake in CMEI. However, iron intake was well below the recommended levels according to the National Education Development Fund resolution, higher prevalence of anemia was observed in children whose intake of iron, heme iron, and nonheme iron was below the median. Conclusions: In terms of public health, the prevalence of anemia is characterized as a moderate problem in the studied population and demonstrates the need for coordination of interdisciplinary actions for its reduction in CMEI nurseries. Resumo: Objetivo: Identificar a prevalência e os fatores associados à anemia em crianças que frequentam berçários de Centros Municipais de Educação Infantil (CMEI de Colombo-PR. Métodos: Estudo analítico, de caráter transversal, com amostra representativa de 334 crianças obtida por amostragem estratificada por conglomerados, com seleção aleatória de 26 berçários. A coleta de dados foi realizada por meio de entrevista com os

Influencia de la parasitemia sobre los valores de hemoglobina y anemia en niños con malaria por Plasmodium falciparum no complicada: experiencia en un hospital de Tanzania

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Melkzedeck P. Mansi

2007-01-01

Full Text Available Objetivos: Analizar la importancia de la parasitemia, su relación con los valores de hemoglobina y anemia en niños internados con malaria por Plasmodium falciparum no complicada, y su potencial uso como variable en la predicción de la hemoglobina y la anemia. Materiales y Métodos: Se realizó un estudio clínico epidemiológico en el Hospital de Nzega, provincia de Tabora, Tanzania entre el 2001-2005, haciendo el diagnóstico con gota gruesa y extendido para investigar la presencia de hemoparásitos. Resultados: En el período de estudio fueron evaluados 165 pacientes con una edad media de 4,1 años (61,2% <5 años. La malaria se confirmó en 87,3% de ellos (100% por P. falciparum. La densidad parasitaria media fue de nueve parásitos por cada 200 glóbulos blancos (IC95% 6,69-11,24 y su Hb 8,4 (±1,6g/dL (82,42% con anemia. La edad y la parasitemia fueron predictores significativos de la anemia (F=13,622; p<0,001, teniendo mayor importancia la parasitemia (p=0,001 que la edad (p=0,014. Conclusión: El nivel de parasitemia de P. falciparum se asocia significativamente con menores niveles de hemoglobina en niños.

A vivência da sexualidade por adolescentes portadoras de deficiência visual La vivencia de la sexualidad por adolescentes portadores de deficiencia visual The experience of sexuality by visually impaired adolescents

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Camilla Pontes Bezerra

2010-09-01

Full Text Available Devido às transformações ocorridas na adolescência, as indefinições que a acompanham, somadas à deficiência visual, justifica-se um estudo sobre a vivência da sexualidade das adolescentes portadoras de deficiência visual inseridas na sociedade e na comunidade escolar. Foram entrevistadas cinco adolescentes em um Centro de Apoio Pedagógico, com questões que buscaram o conhecimento e a compreensão sobre as causa da sua deficiência visual, composição e orientações familiares, experiência afetivo-sexual e o nível de conhecimento acerca de assuntos relacionados à sexualidade, dentre eles métodos contraceptivos e doenças sexualmente transmissíveis. Os resultados mostram que estas adolescentes apresentam as mesmas características de desenvolvimento da sexualidade da sua faixa etária, embora possuam características individuais. Percebeu-se o desconhecimento sobre métodos contraceptivos e doenças sexualmente transmissíveis com informações superficiais. Torna-se imprescindível que o conhecimento se faça de forma acessível para esta população.En razón de las transformaciones sufridas durante la adolescencia, las indefiniciones que a acompañan, sumándose la deficiencia visual, se justifica un estudio sobre la experiencia de la sexualidad de las adolescentes afectadas por deficiencia visual insertas en la sociedad y en la comunidad escolar. Fueron entrevistadas cinco adolescentes en un Centro de Apoyo Pedagógico con preguntas que buscaron el conocimiento y comprensión de la causa de su deficiencia visual, composición y orientaciones familiares, experiencia afectivo-sexual, nivel de conocimientos acerca de asuntos relacionados con la sexualidad, sin excluir métodos anticonceptivos y enfermedades de transmisión sexual. Los resultados muestran que estas adolescentes presentan las mismas características de desarrollo de la sexualidad de su faja etaria, sin embargo poseen características particulares. Se percibió el

Anemia Aplástica e Gravidez: Relato de Caso Aplastic Anemia and Pregnancy: A Case Report

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Rosiane Alves de Sousa Teles

2002-06-01

Full Text Available A anemia aplástica é distúrbio caracterizado por pancitopenia e medula óssea hipocelular, com substituição gordurosa dos elementos e sem nenhum sinal de transformação maligna ou doença mieloproliferativa. Acomete geralmente adultos jovens e idosos, sem preferência sexual. A maioria dos casos é adquirida, mas pode ocorrer hereditariamente, por distúrbio molecular (anemia de Fanconi. A associação com gravidez é rara, estando relacionada com alta morbidade e mortalidade materna e fetal. Os autores descrevem o caso de uma paciente com anemia aplástica, diagnosticada previamente, cuja gestação complicou com infecção do trato urinário, doença hipertensiva específica da gestação e restrição de crescimento fetal, com parto prematuro eletivo. Apesar das condições adversas na gravidez e parto, mãe e recém-nascido tiveram evolução clínica satisfatória.Aplastic anemia is characterized by a circulating pancytopenia, hypocellularity, and fatty replacement of cellular marrow elements, without evidence of malignant transformation or myeloproliferative disease. It usually affects young and senior adults, without any sexual preference. Most cases of aplastic anemia are acquired, but the disease may also be inherited due to a molecular disorder (Fanconi's anemia. Aplastic anemia in pregnancy is an extremely rare condition with high maternal and fetal morbidity and mortality rates. The authors describe a case of a patient with previously diagnosed aplastic anemia, whose pregnancy was complicated with urinary tract infection, preeclampsia and fetal growth restriction, with elective preterm birth. In spite of the adverse conditions in pregnancy and delivery, mother and newborn had a satisfactory clinical evolution.

Recomendaciones para el diagnóstico y manejo de la anemia por déficit de hierro en la mujer embarazada

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Daniel Ernst

2017-05-01

Full Text Available La anemia es una condición altamente prevalente a nivel mundial y, el déficit de hierro, la causa más frecuente, sin excepción; la mujer embarazada está particularmente en riesgo dada la mayor demanda de hierro que la gestación significa. La anemia se asocia a mayor morbilidad y mortalidad materno-perinatal. En mujeres embarazadas sin anemia, la prevención, mediante el uso de multivitamínicos que contienen hierro en dosis de 30-60 mg de hierro elemental, ha demostrado ser efectiva y se recomienda durante todo el embarazo. En casos de anemia, el diagnóstico de déficit de hierro se establece cuando la ferritina es menor a 30 ug/L y/o la saturación de transferrina es menor a 20%. La severidad de la anemia y la situación temporal en el embarazo, son factores modificantes del tratamiento. En mujeres embarazadas, con hemoglobina ≥9.0 g/dL y que tengan <34 semanas de embarazo, la indicación es tratamiento con hierro oral, en dosis de 100 mg al día, en días alternos, hasta normalizar los parámetros antes mencionados. Si la hemoglobina es <9.0 g/dL, o el embarazo es ≥34 semanas, el uso de hierro intravenoso ha demostrado ser más efectivo en corregir la anemia y el déficit de hierro y en disminuir la morbilidad materno-perinatal. En estos casos, sugerimos el uso del hierro carboximaltosa, dado su perfil de seguridad y efectividad favorable. Recomendamos conocer y practicar estas recomendaciones para el diagnóstico y manejo de la anemia por déficit de hierro durante el embarazo.

Malaria and malnutrition in children and household food insecurity: a review

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Uscátegui Peñuela, Rosa Magdalena; Corrales Agudelo, Lady Vanessa; Pérez Tamayo, Eliana María; Correa Botero, Adriana; Manjarrés Correa, Luz Mariela; Carmona Fonseca, Jaime; Estrada Restrepo, Alejandro

2009-01-01

Antecedentes: la malaria, la desnutrición y la inseguridad alimentaria, son problemas de salud pública en Colombia, que deben estudiarse integradamente. Objetivo: describir la relación entre morbimortalidad por malaria con desnutrición proteico-calórica, anemia y deficiencia de vitamina A y de zinc en los niños e inseguridad alimentaria en sus hogares, al igual que el efecto de los suplementos poblacionales de retinol, hierro y zinc sobre morbimortalidad por malaria. Metodología: se consultar...

Anemias hemolíticas

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Ricardo Cediel Ángel

1957-04-01

Full Text Available Hayem (1898 y más tarde Widal (1907 señalaron que, al paso que la forma congénita clásica de anemia hemolítica de Minkowski y Chauffard a menudo causaba pocos síntomas, otro tipo que ellos clasificaron como adquirido, con frecuencia' se asociaba con anemia severa y acentuada incapacidad. Incluyeron allí casos de excesiva destrucción de sangre asociada a diversas infecciones ó intoxicaciones lo mismo que casos de etiología desconocida. Chauffard fue capaz de demostrar autohemolisinas en el suero de unos pocos casos de anemia hemolítica aguda adquirida y se refirió a ellos como "ictericias hemolisínicas". Sin embargo por muchos años existió la duda de que hubiera un verdadero tipo de anemia hemolítica adquirida y muy poco fue tenida en cuenta la posibilidad de que pudiera jugar papel en estos casos una reacción inmunológica.

A hepcidina como parâmetro bioquímico na avaliação da anemia por deficiência de ferro Hepcidin as a biochemical parameter for the assessment of iron deficiency anemia

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Andrea dos Reis Lemos

2010-01-01

Full Text Available A anemia por deficiência de ferro caracteriza-se como o mais prevalente problema nutricional em todo o mundo. Nesta revisão reuniu-se informações a respeito do metabolismo da hepcidina, avaliando-se seu valor como parâmetro bioquímico na anemia por deficiência de ferro. Realizou-se um levantamento bibliográfico nas bases de dados PUBMED e LILACS, período 2006-2010, referentes à hepcidina como um biomarcador para a regulação do metabolismo do ferro. Foram localizados 35 estudos publicados em revistas internacionais e um estudo sobre o assunto em revista nacional. A produção de hepcidina é regulada homeostaticamente pela anemia e hipóxia. Quando a oferta de oxigênio está inadequada ocorre diminuição do nível de hepcidina. Consequentemente, maior quantidade de ferro proveniente da dieta e dos estoques dos macrófagos e hepatócitos se tornam disponíveis. A hepcidina possui a função de se ligar à ferroportina, regulando a liberação do ferro para o plasma. Quando as concentrações de hepcidina estão baixas, as moléculas de ferroportina são expostas na membrana plasmática e liberam o ferro. Quando os níveis de hepcidina aumentam, a hepcidina liga-se às moléculas de ferroportina induzindo sua internalização e degradação, e o ferro liberado diminui progressivamente. Aparentemente o desenvolvimento do diagnóstico e terapia da anemia baseados no bioindicador hepcidina pode oferecer uma abordagem mais efetiva. Estudos epidemiológicos são necessários para comprovar o valor da hepcidina no diagnóstico diferencial das anemias, incluindo protocolos de amostragem para análise, com padronização similar às utilizadas em outras avaliações bioquímicas, e estabelecimento de pontos de corte para a expressão urinária e plasmática desse peptídeo.Iron deficiency anemia is the most prevalent nutritional problem in the world. Information on the metabolism of hepcidin and its possible significance as a biochemical

Anemia in Mexican women: results of two national probabilistic surveys Anemia en mujeres mexicanas: resultados de dos encuestas nacionales probabilísticas

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Teresa Shamah-Levy

2009-01-01

Full Text Available OBJECTIVE: To describe the prevalence of anemia in Mexican women and analyze its trends with information from the last two national nutrition surveys. MATERIAL AND METHODS: The prevalence of anemia in women was analyzed. Anemia was adjusted by socioeconomic profile and by potentially explanatory variables. RESULTS: The overall prevalence of anemia for pregnant women was 20.2% (95% CI 15.9, 26.2% and 15.5% for non-pregnant women (95% CI 14.7, 16.4%. The prevalence of anemia in women decreased from 1999 to 2006 in all socioeconomic profiles. Adolescent women living in the northern and in the southern regions had a greater risk of anemia than those in Mexico City (p= 0.05. Significant risk was found among low socioeconomic level (pOBJETIVO: Describir la prevalencia de anemia en mujeres y analizar su tendencia a través de las dos últimas encuestas nacionales de nutrición. MATERIAL Y MÉTODOS: Se analizó la prevalencia de anemia en mujeres. La prevalencia de anemia se ajustó por perfil socioeconómico y por posibles variables que la expliquen. RESULTADOS: La prevalencia global de anemia fue de 20.2% (IC95% 15.9, 26.2% para mujeres embarazadas y de 15.5% (IC95% 14.7, 16.4% para mujeres no embarazadas. La prevalencia de anemia en mujeres disminuyó de 1999 a 2006 en todos los niveles socioeconómicos. Las mujeres adolescentes que viven en las regiones norte y sur tuvieron mayor riesgo de anemia que las que viven en la Ciudad de México (p= 0.05. Se encontró un riesgo significativo asociado con el nivel socioeconómico bajo (p< 0.06. La mayor paridad resultó ser un factor de riesgo significativo (p< 0.05. CONCLUSIONES: Aun cuando la presencia de anemia en mujeres en edad reproductiva en México ha disminuido, continúa siendo un problema de salud pública.

Contractura axilar por quemadura tratada con Integra®

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Roa G,Ricardo; Las Heras F,Rocío; Piñeros B,José L; Correa S,Gerardo; Norambuena B,Hernán; Marré N,Diego

2011-01-01

Las quemaduras axilares severas son un accidente infrecuente que evolucionan a la retracción generando deficiencias cosméticas y funcionales. Estas cicatrices son difíciles de tratar por las características anatómicas del área, donde la corrección de un vector de movimiento puede alterar otro. Objetivo: Mostrar nuestros resultados utilizando el sustituto cutáneo Integra® en el tratamiento de cicatrices retráctiles axilares por quemadura. Pacientes y Métodos: Se recolectaron antecedentes médic...

Anemia hemolítica causada por Indigofera suffruticosa (Leg. Papilionoideae em bovinos Hemolytic anemia caused by Indigofera suffruticosa (Leg. Papilionoideae in cattle

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José Diomedes Barbosa Neto

2001-03-01

Full Text Available As partes aéreas de Indigofera suffruticosa Mill. (família Leg. Papilionoideae, planta incriminada pelos criadores de diversas áreas do Nordeste por doença caracterizada por hemoglobinúria em bovinos, foram administradas por via oral a seis bovinos, em doses diárias repetidas de 10 a 40 g/kg, Todos os animais experimentais apresentaram hemoglobinúria, porém passageira, apesar continuidade da administração da planta. Dois desses bovinos não apresentaram manifestações adicionais, um terceiro animal evidenciou manifestações leves, e os três outros, sintomas adicionais de intensidade moderada: apatia, mucosas visíveis de coloração esbranquiçada, pêlos arrepiados, anorexia, diminuição da freqüência e intensidade dos movimentos ruminais, taquicardia, pulso venoso positivo e dispnéia. Antes da crise hemolítica a urina apresentava coloração verde azulada. Nenhum animal experimental morreu, porém um foi sacrificado durante a fase hemoglobinúrica. À necropsia observaram-se anemia, bexiga contendo urina cor de vinho tinto, rins aumentados de volume com coloração marrom-escura, fígado, na superfície e ao corte, de coloração azulada com lobulação perceptível. As principais alterações histológicas foram verificadas no fígado, sob forma de necrose coagulativa e tumefação e/ou microvacuolização citoplasmática dos hepatócitos, e no rim representadas por acentuada nefrose, associada a grande quantidade de filtrado e/ou hemoglobina nos espaços de Bowman dentro de túbulos e do citoplasma das células epiteliais.The aereal parts of Indigofera suffruticosa Mill. (family Leg. Papilionoideae were force-fed fresh to 6 bovines in daily doses of 10 to 40 g/kg. Cattle breeders of various parts of the Northeast of Brazil accuse this plant as the cause of a non-fatal disease characterized by hemoglobinuria. The disease occurs only in years when the plant proliferates well invading the native pastures. All experimental

Interferentes eritrocitários e ambientais na anemia falciforme

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Naoum Paulo C.

2000-01-01

Full Text Available A anemia falciforme tem um desenvolvimento clínico extremamente variável que se caracteriza principalmente por diferentes graus de intensidade da anemia hemolítica. As razões dessa variabilidade são parcialmente conhecidas na expressão fenotípica da doença. Apesar de ter um mesmo defeito genético, a anemia falciforme pode estar associada com níveis diferentes de Hb Fetal e interações com talassemia alfa que atuam como modeladores genéticos da doença. Entretanto, outros defeitos genéticos dos eritrócitos, com destaques para a deficiência de G-6PD, a esferocitose e as deficiências de enzimas anti-oxidantes (SOD, GPx e catalase certamente interferem no curso clínico da doença. Os diferentes haplótipos da Hb S denominados por Banto, Benin, Senegal, Camarões e Asiático, tem sido apontados também como possíveis causas da heterogeneidade fenotípica da anemia falciforme. Toda essa diversidade que caracteriza a anemia falciforme está, em parte, relacionada à sua origem multicêntrica e que envolvem populações com diferentes anormalidades genéticas de proteínas e enzimas eritrocitárias. Por outro lado, além desses fatores caracterizados como interferentes eritrocitários, há os interferentes do meio ambiente em que está inserido o doente com anemia falciforme. Entre os interferentes ambientais destacam-se as situações sociais, econômicas e culturais do doente, e que tem influência no curso de sua doença. Diante desse quadro complexo e interativo, o presente artigo mostra a influência de certos interferentes eritrocitários e ambientais na anemia falciforme. Ao finalizar o artigo é proposto um protocolo de monitoramento laboratorial das síndromes falcêmicas, com destaque para a anemia falciforme.

Ingesta de hierro dietario en mujeres adolescentes de instituciones educativas

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Mabel Vila; Margot Quintana

2008-01-01

Introducción: La anemia por deficiencia de hierro es un problema de salud pública. La baja ingesta de hierro dietario es una de sus causas. Objetivo: Estimar la ingesta de hierro dietario en mujeres adolescentes. Diseño: Estudio descriptivo, transversal. Lugar: Instituciones educativas del distrito de Ancón. Participantes: Trescientos cincuenticinco mujeres adolescentes estudiantes del nivel secundario, elegidas en forma aleatoria. Intervenciones: Previo consentimiento informado, se aplicó un...

Prevalencia de anemia en escolares de la zona amazónica de Ecuador

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Quizhpe Edy

2003-01-01

Full Text Available OBJETIVO: Determinar la prevalencia de anemia en niños campesinos de edad escolar en la región amazónica de Ecuador. MÉTODOS: Se realizó un estudio transversal durante los meses de mayo a octubre de 2000 en dos cantones de la provincia de Orellana, al noreste de Ecuador. Se eligieron 17 escuelas aleatoriamente hasta completar el tamaño muestral deseado, que fue de 626 niños. Se recogieron los datos demográficos y antropométricos (peso y talla; se determinaron los valores de hemoglobina y de protoporfirina eritrocitaria, y se analizaron muestras de heces en busca de infestación por parásitos. RESULTADOS: La prevalencia general de anemia fue de 16,6% y de los escolares afectados, 75,5% tenían anemia por déficit de hierro. La prevalencia de desnutrición crónica moderada fue de 28,8% y la de desnutrición crónica grave, de 9,3%. Asimismo, se encontró una prevalencia de desnutrición aguda moderada de 8,4% y de desnutrición aguda grave de 3,4%. Las infecciones parasitarias fueron muy frecuentes (82,0%. Los parásitos más comunes fueron Entamoeba coli (30,3% y Ascaris lumbricoides (25,0%. No se encontró ninguna relación entre la prevalencia de anemia y anemia por déficit de hierro por un lado, y los indicadores nutricionales o de infección parasitaria por el otro. CONCLUSIÓN: La anemia no es un problema grave de salud pública en la población estudiada. No obstante, la elevada prevalencia de niños con desnutrición crónica apunta a la necesidad de mejorar las características de la dieta. La falta de asociación entre la prevalencia de desnutrición y la anemia podría deberse a una baja biodisponibilidad o absorción de hierro, más que a una ingestión insuficiente. Se necesitan estudios que evalúen el tipo de dieta consumida habitualmente por esta población.

Deficiencia de Vitamina A y Estado Nutricional Antropométrico en niños MarginalesUrbanos y Rurales en el Estado Zulia, Venezuela

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Amaya-Castellanos, Daisy; Viloria-Castejón, Haydée; Ortega, Pablo; Gómez, Gisela; Urrieta, Jesús R; Lobo, Pablo; Estévez, Jesús

2002-01-01

El presente estudio transversal fue realizado para estimar la prevalencia de deficiencia de vitamina A (DVA) y desnutrición proteico-energética en una población infantil (24 a 85 meses) de tres barrios marginales urbanos de Maracaibo Estado Zulia, Venezuela (n=173) y de una zona rural (n=34), vecina a Maracaibo, por medio del análisis del retinol sérico y mediciones antropométricas, aplicando puntuación Z a los indicadores Talla//Edad (ZT//E); Peso//Edad (ZP//E) y Peso//Talla (ZP//T), compara...

¿Por qué no leemos?: Propuestas didácticas

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Fragero Guerra, Carmen

2014-01-01

Reflexión y propuesta didáctica sobre la lectura. El texto está dirigido a los estudiantes de Grado de magisterio para que reflexionen sobre su competencia literaria y comprensión lectora. Solo si ellos han reflexionado previamente sobre sus problemas como lectores de obras literarias y los han resuelto, motivarán a sus futuros alumnos. Por un lado, enumero la carencia de habilidades y conocimientos del “no lector”, por otro, sugiero posibles soluciones a estas deficiencias. Finalmente pro...

El riego por chorro intermitente: un sistema prometedor

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Hernando Buriticá

1981-07-01

Full Text Available A través de la historia el hombre se ha ingeniado varios sistemas para suplir las deficiencias de agua que las condiciones naturales de clima han impuesto para el desarrollo de la agricultura: desvió ríos, construyó canales y reservorios y entregó el agua a los cultivos empleando variados sistemas de riego. En este caso haremos referencia al riego por chorro intermitente.

Anemia entre pre-escolares - um problema de saude publica em Belo Horizonte, Brasil

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Thais de Souza Chaves de Oliveira

2014-01-01

Full Text Available O artigo tem por objetivo determinar a prevalência de anemia em crianças matriculadas em creches da regional Centro-Sul de Belo Horizonte (MG, identificando fatores biológicos e socioeconômicos associados. Estudo transversal descritivo realizado em 18 creches. Foram avaliadas 373 crianças com base em amostragem estratificada por instituição participante. A hemoglobina (Hb sérica foi determinada por punção capilar e leitura em β-hemoglobinômetro, adotando-se pontos de corte para anemia de Hb < 11,0g/dL para crianças de seis a 60 meses e Hb < 11,5g/dL para aquelas com idade superior, preconizados pela OMS. O estado nutricional foi definido por aferição do peso e altura e confecção dos índices Peso/Idade (P/I, Estatura/Idade (E/I e IMC/Idade (IMC/I. Entre os participantes 54% eram meninas. A média de idade foi de 38,1 ± 6,2 meses. A prevalência global de anemia foi de 38,3%, sendo superior nas crianças com idade inferior ou igual a 24 meses (56,1%. Encontrou-se associação significativa entre anemia e os fatores menor idade da criança, menor idade materna e baixa renda familiar. O estudo mostrou que anemia em crianças de creches de Belo Horizonte constitui relevante problema de saúde pública, sinalizando a necessidade de se implantar ações específicas para mitigação dos riscos por ele apontados.

Galactosemia: diagnóstico de 5 casos con deficiencia de transferasa

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Enna Gutiérrez García

2001-06-01

Full Text Available Se presenta el estudio bioquímico realizado en el Centro Nacional de Genética Médica, a 5 niños, remitidos por sospecha clínica de padecer un error innato del metabolismo de los carbohidratos. Se les realizó la cromatografía en capa fina para la detección de estas sustancias en orina, y se halló una banda al nivel de galactosa. Posteriormente se procedió a la cuantificación del metabolito en sangre, y se detectó a éste elevado en ella. El diagnóstico final consistió en comprobar la deficiencia de la enzima galactosa-1-fosfato uridiltransferasa eritrocitaria, por el método espectrofotométrico; se comprobó también el carácter de portadores del gen deficiente, en los padres de los 5 niños.The biochemical study of 5 children who were referred to the National Center of Medical Genetics because they were clinically suspected of suffering from an inborn error of the carbohydrate metabolism is presented. Thin layer chromatography was carried out to detect these substances in urine and a band was found at the galactose level. A high level of metabolites in blood was found on quantifying them. The final diagnosis consited in demonstrating the deficiency of erythrocytic galactose-1-phosphate uridyltransferase by the spectrophotometric method. The character of carriers of the deficient gene was also proved among the parents of the 5 children.

Anemia en el embarazo, un problema de salud que puede prevenirse

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Espitia De La Hoz, Franklin; Orozco Santiago, Lilian

2013-01-01

Introducción: la anemia es el trastorno nutricional más frecuente en el mundo, y debido a que en el embarazo existe una gran demanda de hierro, se constituye en un importante riesgo de desarrollar anemia ferropénica. La anemia es la alteración hematológica más diagnosticada durante la gestación, por lo que todas las gestantes están en riesgo de padecer anemia en el embarazo, siendo más frecuente en países subdesarrollados. Es referida como un proceso dilucional secundario al aumento del volum...

Deficiencias en la oportunidad de la atención a pacientes en los servicios de urgencias

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Moros-Portilla, Santiago; Jimenez-Peña, Oscar Mauricio

2017-01-01

El compromiso personal de los profesionales de salud, como factor importante, aunque poco explorado para mejorar la oportunidad en la atención en salud en los Servicios Médicos de Urgencias, puede producir deficiencias en la calidad de la atención, generando a su vez insatisfacción en los pacientes y en sus familias. Estas deficiencias son el resultado de múltiples causas sistémicas y organizacionales; sin embargo, las Instituciones Prestadoras de Salud tienen un margen de acción limitado par...

Profilaxia da anemia ancilostomótica: sindrome de carencia Prophylaxis of Hookworm Anemia-carencial syndrome

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W. O. Cruz

1945-04-01

Full Text Available É apresentada uma revisão das recentes aquisições na anemia ancilostomótica, assinalando a importância de alimentação qualitativamente deficiente junto á infestação helmíntica na gênese desta doença. Acentuou-se que a anemia ancilostomótica é uma doença de carência. Profilaxia clássica da Ancilostomose resume-se em evitar a infestação do homem pelos ancilostomídeos. Critica-se a aplicabilidade destas medidas e eficiência das mesmas no que diz respeito á incidência da anemia. O presente trabalho mostra aquisições preliminares sôbre fundamentos de uma profilaxia de carência (tipo profilaxia do bócio endêmico da anemia ancilostomótica, baseada na administração de alimentos contaminados por um sal de ferro. As misturas sulfato ferroso-farinha de mandióca e citrato férrico amoniacal-caldo de feijão, mostraram-se eficientes em prevenir a queda das cifras hemáticas durante largos períodos de tempo em indivíduos maciçamente infestados (6-8 meses. Não foi verificada a dose diária mínima eficiente dêstes sais, obtendo-se resultados satisfatorios mesmo com 0.1 g diária de sulfato ferroso (correspondendo a 0.037 g de ferro metálico. Numerosos alimentos e sais de ferro foram experimentados com resultados infrutíferos por diferentes razões. A influência dos helmintos, pela hemorragias intestinais que acarretam poude ser mais uma vez estudada, nos casos de sais de ferro administrados em doses ineficientes ou em períodos de prova sem medicação marcial. É proposta nova classificação de intensidade de infestação, levando em consideração o conhecido fato de ser a atividade dos helmintos, exclusivamente expoliadora. Em conclusão, nos parece exequível a profilaxia da anemia ancilostomótica mediante ingestão de alimentos contaminados por quantidades eficientes de sais de ferro. Êste método profilático extremamente econômico será na prática, provàvelmente, muito superior aos métodos de profilaxia

Caracterización de un proceso de biorremediación de hidrocarburos en deficiencia de nitrógeno en un suelo de la Patagonia Argentina

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Acuña, Adrián Javier; Pucci Ceima, Oscar Héctor; Pucci Bissetta, Graciela Natalia

2008-01-01

La zona central de la Patagonia, Argentina, se encuentra sometida a explotación petrolera y sus suelos se caracterizan por ser deficientes en nitrógeno. Esto causaría un efecto negativo en los procesos de atenuación natural que se desarrollan en los suelos contaminados con hidrocarburos. El objeto de este estudio fue determinar cual es el efecto de la deficiencia de nitrógeno sobre la biodegradación de los hidrocarburos en un suelo de la Patagonia, Argentina. Se trabajó con tres micr...

Glicanos de la vellosidad trofoblástica en la anemia ferropénica y la preeclampsia grave

OpenAIRE

Gómez-Gutiérrez, Alejandra María; Parra-Sosa, Beatriz Elena; Bueno-Sánchez, Julio Cesar

2015-01-01

Introducción: Las glicoproteínas de la membrana del sincitiotrofoblasto (STB) se encuentran en contacto con la sangre materna, por lo que pueden participar en la comunicación en la interface materno-fetal. Objetivo: caracterizar patrones de glicanos de la vellosidad trofoblástica de mujeres sanas, anémicas por deficiencia de hierro y preeclámpticas graves de inicio temprano. Materiales y métodos: se obtuvieron extractos proteínicos de vellosidad placentaria de tercer trimestre y se determinó ...

Eficacia del hierro aminoquelado en comparación con el sulfato ferroso como fortificante de un complemento alimentario en preescolares con deficiencia de hierro, Medellín, 2011

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Maylen Liseth Rojas

2013-09-01

Full Text Available Introducción. La disminución de los depósitos de hierro constituye el primer eslabón de la cadena conducente a la deficiencia de hierro, la carencia nutricional más prevalente y principal causa de anemia en todo el mundo, situación que puede prevenirse mediante la fortificación de alimentos. Objetivo. Comparar la eficacia del hierro aminoquelado con el sulfato ferroso como fortificante de un complemento alimentario en preescolares con deficiencia de hierro. Materiales y métodos. Se llevó a cabo un ensayo clínico triple ciego con distribución aleatoria de grupos. Se analizaron 56 preescolares con deficiencia de hierro (ferritina menor de 24 ng/ml a los que se les dio diariamente 13 g de leche con 12,5 mg de hierro. Después de dos meses se midieron los niveles de hemoglobina, hematocrito y ferritina sérica. Resultados. En el grupo con sulfato ferroso la concentración de ferritina sérica aumentó de 18,8 a 24,1ng/ml, mientras que dicha variación fue de 18,4 a 29,7 ng/ml con el hierro aminoquelado, en ambos casos con diferencias significativas. El nivel de ferritina final difirió según el grupo de estudio, siendo mayor en el grupo con hierro aminoquelado (p=0,022. La hemoglobina y el hematocrito no variaron después de la intervención. Las reacciones adversas en el grupo con sulfato ferroso fueron de 35,7 %, en contraste con el 42,9 % en el grupo con hierro aminoquelado; cinco niños presentaron infección delas vías respiratorias, sin diferencias estadísticas. Conclusiones. Los dos compuestos aumentan los niveles de ferritina, siendo mayor el aumento entre quienes toman leche con hierro aminoquelado. No fue diferente la incidencia de reacciones adversas o de infecciones entre los grupos. Identificador en Clinicaltrials.gov: NCT01412723 doi: http://dx.doi.org/10.7705/biomedica.v33i3.775

Deficiencias de las células fagocíticas

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Diana García de Olarte

1988-01-01

Full Text Available Se presenta una revisión sobre las deficiencias de las células fagocíticas; se consigna Información básica y clínica sobre defectos de la adherencia, la quimiotaxis, la fagocitosis y la actividad microbicida. We present a review of phagocytic-cell deficiency; both clinical and basic Information Is Included for such aspects as defects of adherence, chemotaxis, phagocytosis and mlcrobicidal activitles.

Anemia prevalence and risk factors in pregnant women in an urban area of Pakistan.

Science.gov (United States)

Baig-Ansari, Naila; Badruddin, Salma Halai; Karmaliani, Rozina; Harris, Hillary; Jehan, Imtiaz; Pasha, Omrana; Moss, Nancy; McClure, Elizabeth M; Goldenberg, Robert L

2008-06-01

Anemia affects almost two-thirds of pregnant women in developing countries and contributes to maternal morbidity and mortality and to low birthweight. To determine the prevalence of anemia and the dietary and socioeconomic factors associated with anemia in pregnant women living in an urban community setting in Hyderabad, Pakistan. This was a prospective, observational study of 1,369 pregnant women enrolled at 20 to 26 weeks of gestation and followed to 6 weeks postpartum. A blood sample was obtained at enrollment to determine hemoglobin levels. Information on nutritional knowledge, attitudes, and practice and dietary history regarding usual food intake before and during pregnancy were obtained by trained interviewers within 1 week of enrollment. The prevalence of anemia (defined by the World Health Organization as hemoglobin hemoglobin from 9.0 to 10.9 g/dL) and 14.8% had moderate anemia (hemoglobin from 7.0 to 8.9 g/dL). Only 0.7% were severely anemic (hemoglobin education, pregnancy history, iron supplementation, and height showed that drinking more than three cups of tea per day before pregnancy (adjusted prevalence odds ratio [aPOR], 3.2; 95% confidence interval [CI], 1.3 to 8.0), consumption of clay or dirt during pregnancy (aPOR, 3.7; 95% CI, 1.1 to 12.3), and never consuming eggs or consuming eggs less than twice a week during pregnancy (aPOR, 1.7; 95% CI, 1.1 to 2.5) were significantly associated with anemia. Consumption of red meat less than twice a week prior to pregnancy was marginally associated with anemia (aPOR, 1.2; 95% CI, 0.8 to 1.8) but was significantly associated with lower mean hemoglobin concentrations (9.9 vs. 10.0 g/dL, p = .05) during the study period. A subanalysis excluding women with mild anemia found similar associations to those of the main model, albeit even stronger. A high percentage of women at 20 to 26 weeks of pregnancy had mild to moderate anemia. Pica, tea consumption, and low intake of eggs and red meat were associated with

Aspectos Históricos de la deficiencia de Yodo en América

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Mario Paredes Suárez

2001-08-01

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Con motivo de la llamada “Reunión de Quito”, organizada para valorar los avances de los Programas de Control del Bocio y Cretinismo Endémicos ejecutados en los diferentes países latinoamericanos, recibimos el libro del Profesor Hetzel en el cual el autor acuña la frase “SOS para un Billón”; allí hace un llamado a la conciencia internacional sobre el riesgo que tienen un billón de personas en el mundo de padecer deficiencia de yodo, a pesar de todas las medidas que se han hecho para solventar este problema (1.

Este aspecto llama la atención al considerar que la deficiencia de yodo en las comunidades mundiales, aun se halla en vigencia; lo más alarmante es que si bien es verdad en muchos países se ha logrado el acceso a fuentes de yodo por yodación de la sal u otros vehículos, aun existenÊ áreas en el mundo en las cuales la población no tiene esta oportunidad. Aparte de esto las consecuencias de la carencia de yodo, particularmente la deficiencia mental y el retraso del crecimiento y desarrollo, hacen de este panorama un escenario sombrío para millones de niños en el ámbito universal.

América Latina no escapa a esta realidad, pues la carencia de yodo en su población ha tenido resultados biológicos y sociales de enorme impacto, características propias de los países de poco desarrollo económico y con sistemas frágiles que lo alimentan.

Esta patología tan frecuente en América y en particular en las zonas del altiplano andino, ha sido objeto de innumerables estudios y publicaciones que han tratado de hacer una retrospectiva epidemiológica que explique las raíces y orígenes de este llamado “mal andino” y que tanto daño ha hecho a todas las comunidades de Latinoamérica.

Se tiene conocimiento de un documento chino que data de cerca de 3000 años A.C. que contiene, posiblemente la primera descripción de la presencia del bocio. Así mismo el papiro de Ebers del antiguo Egipto

Biomarcadores del metabolismo y nutrición de hierro

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Carmen Gloria Sermini

Full Text Available RESUMEN La anemia por deficiencia de hierro continúa siendo la deficiencia nutricional más abundante en el mundo, y son los lactantes, preescolares, mujeres en edad fértil y embarazadas los grupos de mayor susceptibilidad. Debido a esto es que se hace necesario el conocer los mecanismos de regulación de captación, transporte y absorción del metal a nivel celular, principalmente a nivel del enterocito y, una vez que el hierro entra a la circulación, conocer cuáles son los biomarcadores que permiten realizar un seguimiento del estatus del hierro corporal. En esta revisión mostramos, en primer lugar, cómo se regula la entrada de hierro a nivel de la célula del epitelio intestinal, mostrando las principales proteínas involucradas (transportadores de entrada y salida de hierro, oxido-reductasas, proteína de almacenamiento y, para finalizar, hacemos un recuento de los principales biomarcadores del metabolismo de hierro una vez que este ha entrado y circula por el organismo.

Deficiencia de vitamina D en la edad pediátrica. Una oportunidad de prevención

OpenAIRE

López-González, Desirée; Méndez-Sánchez, Lucía; Guagnelli, Miguel Ángel; Clark, Patricia

2015-01-01

La prevalencia de deficiencia de vitamina D en la población pediátrica ha incrementado en los últimos años y se considera que continúa subdiagnosticada y subtratada. De acuerdo con datos de la Encuesta Nacional de Salud y Nutrición 2006, en México se ha estimado una prevalencia del 16% en niños de 2 a 12 años. La vitamina D desempeña un papel fundamental en la formación y homeostasis del hueso, y consecuentemente en el crecimiento. Su deficiencia se asocia con enfermedades como raquitismo y o...

Manifestaciones cardiovasculares de anemia de células falciformes

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Fernando Manzur

2015-07-01

Full Text Available La anemia de células falciformes es una hemoglobinopatía hereditaria producida por la presencia de hemoglobina S, que disminuye la solubilidad y a través del proceso de polimerización da lugar a hematíes en forma de hoz que obstruyen la red microvascular. Se caracteriza por episodios de daño por isquemia-reperfusión que contribuyen a la disfunción de órganos vitales. El advenimiento de la terapia inductora de hemoglobina fetal, asociada a la profilaxis antibiótica, ha permitido prolongar la supervivencia. Sin embargo, al incrementar la longevidad, las complicaciones cardiovasculares se hacen evidentes con el desarrollo de vasculopatía sistémica, infarto agudo de miocardio, hipertensión arterial pulmonar y disfunción ventricular. El objetivo de este artículo es revisar la fisiopatología y el tratamiento de las principales manifestaciones cardiovasculares en pacientes con anemia de células falciformes.

Fanconi`s anemia and pregnancy: an unusual combination

OpenAIRE

Escalante-Gómez, Carlos; Jiménez-Torrealba, Judith

2008-01-01

La anemia de Fanconi es una falla clásica de la médula ósea, la cual tiene una incidencia de menos de 1 en 100,000 nacidos vivos. Hasta ahora, las pacientes femeninas normalmente no alcanzaban la edad reproductiva y mucho menos lograban el embarazo. Una revisión actual de la literatura identifica solamente 19 pacientes que han logrado el embarazo. Presentamos el caso de una paciente de 16 años portadora de anemia de Fanconi, la cual presenta un embarazo de 30 semanas complicado por un cuadro ...

Estudio de las alteraciones del esmalte en la enfermedad celiaca

OpenAIRE

Bonet Coloma, Cristina

2013-01-01

La enfermedad celiaca (EC) es una enteropatía caracterizada por una intolerancia permanente al gluten, proteína existente en el trigo, centeno, cebada y avena que provoca una lesión severa de las vellosidades intestinales, y se normaliza tras su retirada de la dieta. La sintomatología varía de un paciente a otro dependiendo del daño de la mucosa intestinal. La presentación típica incluye diarrea, pérdida de peso, fatiga, distensión abdominal, vómitos, deficiencias nutricionales y anemia p...

Crecimiento y desarrollo en la drepanocitosis Growth and development in drepanocytosis

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Pedro González Fernández

2006-04-01

Full Text Available La drepanocitosis (D es un grupo de anemias hemolíticas congénitas que incluye: la anemia drepanocítica (SS: 60 % la hemoglobinopatía (SC: 30 % y la S/ß talasemia: 10 %. Son las anemias hemolíticas más frecuentes en el mundo. En Cuba, la incidencia del estado de portador es de 13,2 en negros, 4,1 en mestizos y 0,6 en blancos. En la población general alcanza el 3,08. La afectación del crecimiento y desarrollo en estos pacientes ha sido un tópico muy debatido, y se consideran como posibles causas relacionadas con esta alteración las disfunciones hormonales, las deficiencias nutricionales, los factores socioeconómicos y los trastornos del sistema osteoarticular. Se realiza una revisión sobre estos aspectos en la literatura nacional y extranjera. Se concluye que la deficiencia en el crecimiento parece estar relacionada con la hipoxia tisular causada por la anemia severa, los efectos agudos y crónicos de la vasoclusión, la disfunción endocrina asociada con la anemia, el bajo ingreso dietético, los requerimientos energéticos elevados y el bajo estado socioeconómico.Drepanocytosis is a group of congenital hemolytic anemias that includes drepanocytic anemia (SS: 60.0, hemoglobinopathy (SC: 30.0 and S/ß thalassemia: 10.0. These are the most frequent hemolytic anemias in the world. In Cuba, the incidence of the carrier state is of 13.2 % in black, 4.1 in mestizoes and 0.6 in white individuals. It reaches 3.08 % of the general population. The affectation of growth and development in these patients has been a very discussed topic and the hormonal dysfunctions, the nutritional deficiencies, the socioeconomic factors and the disorders of the osteoarticular system are considered as possible causes related to this alteration. A review of these aspects is made in national and foreign literature. It is concluded that growth deficiency may be related to tissue hypoxia caused by severe anemia, the acute and chronic effects of vasoocclusion, the

Iron deficiency anemia in Tarahumara women of reproductive-age in Northern Mexico Anemia ferropriva en mujeres tarahumaras, en edad fértil, del norte de México

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Joel Monárrez-Espino

2001-10-01

Bonferroni para diferencias de medias. Resultados. La prevalencia de anemia ( Hb±DE fue de 16.1% (140±16 g/l y 25.7% (129±12 g/l para no embarazadas y embarazadas, respectivamente. Las embarazadas en el tercer trimestre y las que estaban lactando durante los primeros seis meses del postparto mostraron las más altas prevalencias de anemia (38.5% y 42.9%, respectivamente. La deficiencia de hierro fue responsable de la mayoría de los casos de anemia encontrada en esta muestra. Conclusiones. Este estudio provee información relevante para desarrollar programas de intervención para tratar y prevenir la anemia ferropriva en este grupo étnico. El texto completo en inglés de este artículo está también disponible en: http://www.insp.mx/salud/index.html

Pernicious anemia

Science.gov (United States)

... malabsorption); Anemia - intrinsic factor; Anemia - IF; Anemia - atrophic gastritis ... of pernicious anemia include: Weakened stomach lining (atrophic gastritis) An autoimmune condition in which the body's immune ...

Deformabilidade eritrocitária na anemia ferropriva Erythrocyte deformability in iron deficiency

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Giuseppina M. Patavino

2006-12-01

Full Text Available A deformabilidade é a característica que permite ao eritrócito normal de 7 a 8 micrômetros (µm circular por capilares de até 3 µm de diâmetro. Esse fenômeno depende da geometria celular, da viscosidade interna e de propriedades visco-elásticas da membrana eritrocitária. Dentre as técnicas de estudo da deformabilidade eritrocitária (DE, como aspiração por micropipeta, filtração e reoscopia, destaca-se a ectacitometria. Esta técnica utiliza um viscosímetro de fluxo laminar no qual as modificações de forma dos eritrócitos são monitoradas continuamente por um feixe de raio laser, processadas por microcomputador, gerando o "Índice de Deformabilidade" (ID, que mede a eliptocitogênese dos eritrócitos quando submetidos a uma força denominada "shear stressl". Alterações de DE foram descritas em diversas situações, como em anemias hemolíticas hereditárias ou auto-imunes. Na anemia ferropriva, os trabalhos são controversos. O presente estudo avalia a DE em 21 pacientes portadores de anemia ferropriva, utilizando a ectacitometria. Os resultados obtidos a partir do ID demonstram DE diminuída nesses doentes, quando comparada ao grupo controle (pDeformability allows the 7 to 8 µm red cell to cirDeformability allows the 7- to 8-µm red blood cells to circulate through capillaries of 3 µm. This phenomenon depends on cellular geometry, internal viscosity and viscoelastic properties of the membrane. Among the various techniques of erythrocyte deformability analysis, such as micropipette aspiration, filtration and reoscopy, we chose ektacytometry. This technique uses a laminar flow viscometry, where red blood cell shape changes are continuously monitored by laser, processed by a computer, generating the "Deformability Index", which shows the elliptocytogenesis of the erythrocyte under "shear stressl" force. Erythrocyte deformability has been described in a number of situations like hereditary or autoimmune hemolytic anemia. In

Manejo obstétrico de la deficiencia hereditaria de antitrombina durante el embarazo y puerperio. Dos casos clínicos

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Milagros Cruz Martínez

2015-12-01

Full Text Available Resumen Introducción: la deficiencia de antitrombina III hereditaria es una rara enfermedad que afecta al 0.02-0.2% de la población. Puede presentar mayor frecuencia de complicaciones y resultados adversos tanto en la madre como en el feto. Se presenta el manejo obstétrico de dos gestaciones consecutivas en una mujer con deficiencia de antitrombina III. Descripción: en ambos embarazos la madre realiza profilaxis de la enfermedad tromboembólica con heparina de bajo peso molecular para evitar la aparición de esta patología tanto en el embarazo como en el puerperio y mejorar el flujo útero-placen-tario. Con respecto a las complicaciones obstétricas, sólo existe un enlentecimiento del crecimiento fetal que obliga a un control obstétrico estricto. En ambas gestaciones los estudios eco-Doppler están dentro de la normalidad lo que permite una conducta expectante, consiguiendo llegar a término. Discusión: la profilaxis con heparina de bajo peso molecular en las gestantes con esta trombofilia y las intervenciones preventivas de factores de riesgo de enfermedad tromboembólica, junto con un control obstétrico adecuado, ha conseguido evitar la apari-ción de complicaciones derivadas de esta patología en el embarazo y en el puerperio. Por otra parte, el control del crecimiento fetal y el estudio Eco-Doppler han permitido asegurar el bienestar fetal no adelan-tando el parto, consiguiendo partos a término.

SÍNTOMAS ASOCIADOS A LA DEFICIENCIA DE BORO EN LA PALMA ACEITERA (Elaeis guineensis JACQ. EN COSTA RICA

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Marco V. Guti\\u00E9rrez-Soto

2013-01-01

Full Text Available El objetivo de este trabajo es brindar información fisiológica relativa a las funciones, la disponibilidad, la economía y la deficiencia de boro en las plantas, con énfasis en la palma aceitera cultivada en Coto, Costa Rica. Se exponen las generalidades sobre la química del boro en el suelo y en las plantas, y se discuten sus posibles funciones estructurales, metabólicas y morfogenéticas. Se resalta su papel en la formación y la estabilidad de la pared celular, el transporte de azúcares, el control de los niveles de auxinas y en el desarrollo reproductivo. Se compara la susceptibilidad relativa de las hojas y las raíces a la deficiencia de boro. Se describen los síntomas de la deficiencia de boro observados en la palma aceitera, los posibles mecanismos causales y los métodos apropiados para su diagnóstico. Se discuten además las terapias, formulaciones químicas y métodos agronómicos disponibles para su corrección.

Seguridad alimentaria, crecimiento y niveles de vitamina A, hemoglobina y zinc en ninos preescolares del nordeste de Brasil

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Dixis Figueroa Pedraza

2014-02-01

Full Text Available El presente estudio buscó analizar la asociación entre la (inseguridad alimentaria y el estado nutricional de niños preescolares asistidos en jardines infantiles. La seguridad alimentaria fue evaluada a través de la Escala Brasileña de Inseguridad Alimentaria (EBIA. El estado nutricional se evaluó a través del peso/edad, talla/edad, hemoglobina, retinol sérico y zinc sérico. Fueron encontradas prevalencias de déficit de estatura (6,2%, déficit de peso/edad (2,1%, deficiencia de vitamina A (24,4%, anemia (15,5% y deficiencia de zinc (15,0%. La inseguridad alimentaria familiar fue caracterizada en 64,2% de las familias predominando la forma leve (32,6%. El estudio concluye que la inseguridad alimentaria estimada por la EBIA no se asoció a los Escore-z de crecimiento ni a las concentraciones de retinol sérico, hemoglobina y zinc sérico.

DIAGNÓSTICO POR PROCESOS DE LA ORGANIZACIÓN DE LA ACTIVIDAD COMERCIAL EN LA EMPRESA PROPES

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Pedro Blas Arteaga Gómez

2003-12-01

Full Text Available

En el presente artículo se expone el resultado de un diagnóstico por proceso realizado en la organización de la actividad comercial de la Empresa Importadora y Proveedora de Productos para la Pesca, PROPES, determinándose la cadena de valor, las características de cada proceso y sus deficiencias y problemas. Por último, se propone un conjunto de soluciones que se encuentran en vías de implementación.

Eficácia e toxicidade da hidroxiuréia em crianças com anemia falciforme Effectiveness and toxicity of hydroxyurea in children with sickle cell anemia

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Michelle C. Silva

2006-06-01

Full Text Available A anemia falciforme é uma doença genética caracterizada pelo alto índice de morbimortalidade, considerada como a mais grave entre as doenças falciformes. As opções terapêuticas mais eficazes atualmente disponíveis para tratamento desta hemoglobinopatia são transplante de medula óssea (TMO e hidroxiuréia (HU. O TMO apesar de ser a medida curativa é considerado de alto risco por apresentar diversos graus de complicações e significativo nível de mortalidade. O uso de HU em crianças portadoras de anemia falciforme tem proporcionado redução de complicações clínicas e aumento significativo na expectativa de vida, por promover elevação dos níveis de hemoglobina fetal, da concentração de hemoglobina e do VCM, bem como redução da hemólise e de eventos vaso-oclusivos. Desse modo, a HU é considerada como melhor opção terapêutica atualmente disponível. Porém, por ser apontada como droga potencialmente carcinogênica, há questionamentos quanto aos benefícios e toxicidades quando utilizada por longo período. Este trabalho teve como proposta, avaliar por meio da revisão literária, os riscos, benefícios e efeitos adversos da hidroxiuréia em crianças.Sickle cell anemia is a genetic disease characterized by a high morbimortality rate, it is considered as the most serious among all sickle cell diseases. The most effective therapeutic options available nowadays for the treatment of this hemoglobinopathy are bone morrow transplantation (BMT and hydroxyurea (HU. BMT is considered a high risk procedure due to the different complications and significant mortality rates. The use of HU for children with sickle cell anemia has reduced the clinical complications and given a significant increase in life expectancy by augmenting the fetal hemoglobin levels and hemoglobin concentrations and reducing cytomegalovirus, as well as reducing hemolysis and vaso-occlusive events. Thus, HU is considered the best therapeutic option currently

Pregnancy Complications: Anemia

Science.gov (United States)

... online community Home > Complications & Loss > Pregnancy complications > Anemia Anemia E-mail to a friend Please fill in ... anemia at a prenatal care visit . What causes anemia? Usually, a woman becomes anemic (has anemia) because ...

Iron-Deficiency Anemia

Science.gov (United States)

... To Health Topics / Iron-Deficiency Anemia Iron-Deficiency Anemia Also known as Leer en español Iron-deficiency ... anemia. Blood tests to screen for iron-deficiency anemia To screen for iron-deficiency anemia, your doctor ...

Anemia (For Parents)

Science.gov (United States)

... Staying Safe Videos for Educators Search English Español Anemia KidsHealth / For Parents / Anemia What's in this article? ... Deficiency Anemia in My Kids? Print What Is Anemia? Anemia is when the level of healthy red ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... To Health Topics / Iron-Deficiency Anemia Iron-Deficiency Anemia Also known as Leer en español Iron-deficiency ... anemia. Blood tests to screen for iron-deficiency anemia To screen for iron-deficiency anemia, your doctor ...

Concepts of anemia among low income Nicaraguan women Conceptos de anemia entre mujeres nicaragüenses de baja renta Conceitos de anemia entre mulheres nicaragüenses de baixa renda

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Rita L. Ailinger

2009-04-01

Full Text Available Anemia is a common health problem among women throughout the world, however, there has been minimal research on women's concepts of anemia. The purpose of this study was to examine concepts of anemia in low income Nicaraguan women. A qualitative design was used. Audio-taped open-ended interviews in Spanish with 14 women were used to obtain data. Tapes were transcribed and content analyzed. The findings indicate that few of the women had biomedically accurate concepts of anemia, such as that it was due to lack of iron from poor eating. Others held folk medical beliefs including home remedies, for example drinking the milk of a mare or beet juice and eating certain foods such as bean soup. Most of the women did not know any symptoms of anemia and a few reported that it can develop into leukemia. These concepts of anemia are instructive for nurses working with patients from Nicaragua and will be useful in developing nursing interventions to alleviate this public health problem.La anemia es un problema de salud común entre las mujeres alrededor del mundo, sin embargo, se han realizado pocas investigaciones sobre los conceptos de anemia entre las mujeres. El propósito de este estudio fue examinar los conceptos de anemia en mujeres Nicaragüenses de bajos ingresos económicos. La investigación fue de orden cualitativa. Para la recolección de datos, se realizaron entrevistas semiestructuradas, grabadas en castellano, con 14 mujeres. Las cintas grabadas fueron transcritas y se realizó un análisis de contenido. Los resultados indican que pocas mujeres poseen conocimientos biomédicos sobre anemia, por ejemplo, la ingestión de alimentos pobres en hierro. Otras expresaron creencias populares, como remedios caseros, ingestión de leche de yegua o jugo de remolacha y ciertos alimentos como sopa de judías. La mayoría de las mujeres no conocía ningún síntoma de anemia y pocas relataron que creían que esta enfermedad podría transformarse en

Iron-deficiency anemia as a subclinical celiac disease presentation in an Argentinian population.

Science.gov (United States)

Lasa, J S; Olivera, P; Soifer, L; Moore, R

There is a wide heterogeneity in the reports of celiac disease prevalence in iron-deficiency anemia patients. To determine the prevalence of celiac disease in patients with iron-deficiency anemia. Adult patients with a diagnosis of iron-deficiency anemia were enrolled for upper endoscopy with duodenal biopsies. Healthy volunteers that underwent upper endoscopy were enrolled as controls. A total of 135 patients with iron-deficiency anemia and 133 controls were enrolled. Celiac disease prevalence was higher in the iron-deficiency anemia group [11.11 vs. 1.51%, OR: 8.18 (1.83-36.55), P=.001). Of the celiac disease patients in the iron-deficiency anemia group, 73.3% had at least one endoscopic sign suggesting villous atrophy, whereas 100% of the celiac disease patients in the control group presented with at least one endoscopic sign. Patients with iron-deficiency anemia have an increased risk for celiac disease. Up to 25% of these patients may not present any endoscopic sign suggesting villous atrophy. Copyright © 2017 Asociación Mexicana de Gastroenterología. Publicado por Masson Doyma México S.A. All rights reserved.

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... Research Home / < Back To Health Topics / Iron-Deficiency Anemia Iron-Deficiency Anemia Also known as Leer en español Iron-deficiency ... iron-deficiency anemia. Blood tests to screen for iron-deficiency anemia To screen for iron-deficiency anemia, your doctor ...

Percepción de los maestros sobre las deficiencias visuales y su incidencia escolar

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Ana FERNÁNDEZ QUEVEDO

2016-05-01

Full Text Available El sentido de la visión constituye la fuente principal de adquisición de información del individuo, de aquí la importancia de un buen diagnóstico y corrección, en su caso, de cualquier anomalía en la misma para un correcto aprendizaje, especialmente en los primeros años de escolarización. En este artículo se exponen los resultados de una encuesta pasada a maestros de centros educativos andaluces mediante la que se pretende poner de manifiesto sus conocimientos sobre las deficiencias visuales que pueden presentar sus alumnos, y la incidencia que podrían tener sobre su rendimiento escolar. Los resultados indican que dicho conocimiento se suele circunscribir a las anomalías de tipo refractivo, considerando que se hallan bien tratadas en sus alumnos. A pesar de la importancia que atribuyen a estas deficiencias sobre el aprendizaje escolar, piensan que otros factores pueden poseer un papel más relevante. Asimismo se consideran partidarios de recibir una formación más completa al respecto.

Análisis descriptivo sobre deficiencias y discapacidades del desarrollo psicomotor en pacientes atendidos en el Instituto Nacional de Rehabilitación 2006 - 2008

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Herminio Teófilo Camacho-Conchucos

2012-04-01

Full Text Available Introducción: La deficiencia constituye la exteriorización directa de las consecuencias de la enfermedad, y la discapacidad es la restricción o ausencia de realizar una actividad debido a una deficiencia. Objetivos: Determinar las deficiencias y discapacidades del desarrollo psicomotor y características de pacientes atendidos en el Departamento de Investigación Docencia y Rehabilitación Integral de las Discapacidades del Desarrollo. Diseño: Estudio observacional, descriptivo, de corte transversal. Lugar: Instituto Nacional de Rehabilitación ‘Dra. Adriana Rebaza Flores’, Callao, Perú. Participantes: Pacientes atendidos de 0 a 7 años con diagnóstico definitivo, sin retardo mental evidente. Intervenciones: De 5 795 pacientes atendidos en el periodo 2006-2008, se obtuvo una muestra de 400, de los cuales se revisó sus historias clínicas. Se describe las deficiencias y discapacidades y sus características. Principales medidas de resultados: Deficiencias y discapacidades del desarrollo psicomotor. Resultados: En el rango de 0 a 7 años, 76,6% fueron de 0 a 2 años; 51% niñas; 54,3% procedía del departamento de Lima, 42,8% de la provincia del Callao. A nivel de distritos de Lima Metropolitana acudieron mayormente del Callao (23,8% y San Martín de Porres (10,6%. Los principales diagnósticos fueron trastorno especifico del desarrollo de la función motriz (17,5%, trastornos específicos mixtos del desarrollo (15%, parálisis cerebral infantil (12%; 91,3% presentó alguna deficiencia, de las cuales las más importantes fueron músculo esqueléticas 66,6%, del órgano de la audición 14,5%, del lenguaje 7,9%, psicológicas 6,8%. Registró discapacidad el 78%; las principales fueron de locomoción 35,9%, de disposición corporal 22,8%, de la comunicación 17,6%. En gravedad de la discapacidad, 11,9% fue severa, 59,3% moderada, 21,1% leve y no aplicable en 7,7%. Conclusiones: Las principales deficiencias y discapacidades fueron m

Hemolytic anemia

Science.gov (United States)

Anemia - hemolytic ... bones that helps form all blood cells. Hemolytic anemia occurs when the bone marrow isn't making ... destroyed. There are several possible causes of hemolytic anemia. Red blood cells may be destroyed due to: ...

Perfiles de personas con deficiencia mental basados en las funciones motrices gruesas

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Isabel María FERRÁNDIZ VINDEL

2009-11-01

Full Text Available RESUMEN: El propósito de este estudio ha sido identificar posibles subtipos de alumnos con Deficiencia Mental basados en funciones motrices gmesas. Se seleccionó un grupo de alumnos, de un centro específico de Deficiencia Mental, que no presentaron deficiencias motóricas asociadas y se les administraron los subtests de motricidad gruesa del «Test Bruininks-Ozeretsky para medir la eficacia motriz». Los cuatro subtipos resultantes mostraron diferentes perfiles de desarrollo motor. A partir de estos resultados, se recomienda diseñar programas específicos que intenten paliar los trastornos motrices gruesos, analizados para cada uno de los subtipos hallados, y realizar adaptaciones curriculares pertinentes, teniendo en cuenta los perfiles motrices estudiados.ABSTRACT: The goal of this work was to identify some different cathegories of mental retarded people, depending on their gross motor functioning. A group of mental retarded people was selected from a special education school. None of theese students presented any associated motor deficiency. The gross motor subtests from the Bruininks-Ozeretsky test were administered in order to evaluate the motor eficiency of these mental retarded people. The resulting four cathegories showed different motor development profiles. From theese results it's recommended to design curricula-based intended to amiliorate the specific gross motor deficits of each group and making didactical schedules taking into account the motor profiles studied.RESUME: Le propos de cette étude est identifier possibles subtypes d'élèves avec déficience mental basses en fonctions motrices grosses. On a selectioné un groupe d'élèves dans un centre especifique d'insuffisance mental qui ne présentent pas insuffisance motoriques associés, on les a passé les subtests de motricité grosse du test Bruininks-Ozeretsky pour mesurer l'efficacité motrice. Les quattre subtypes resultants montrent des différents profils du

Deficiências após a alta medicamentosa da hanseníase: prevalência e distribuição espacial Deficiencias posteriores a alta medicamentosa de hanseniasis: prevalencia y distribución espacial Leprosy-related disabilities after release from multidrug treatment: prevalence and spatial distribution

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Susilene Maria Tonelli Nardi

2012-12-01

Full Text Available OBJETIVO: Estimar a frequência das deficiências físicas em pacientes tratados de hanseníase após alta medicamentosa e analisar sua distribuição espacial. MÉTODOS: Estudo descritivo transversal com 232 pessoas tratadas de hanseníase de 1998 a 2006. As deficiências físicas foram avaliadas pelo Grau de Incapacidades da Organização Mundial da Saúde (GI/OMS e pelo Eye-Hand-Foot (EHF. Os ex-pacientes foram geocodificados pelo endereço de residência e os serviços de reabilitação pelo endereço de sua sede. Foram apresentadas as frequências para o total e para os grupos grau 0, grau 1 e grau 2 do GI-OMS, considerando-se as variáveis clínicas e sociodemográficas na análise descritiva. Foram utilizados os testes t de Student, qui-quadrado (χ2 ou de Fisher, conforme apropriado, considerando-se significativos p OBJETIVO: Estimar la frecuencia de las deficiencias físicas, en pacientes tratados por hanseniasis, posteriores a alta medicamentosa y analizar su distribución espacial MÉTODOS: Estudio descriptivo transversal con 232 personas tratadas por hanseniasis de 1998 a 2006. Las deficiencias físicas fueron evaluadas por el Grado de Incapacidades de la Organización Mundial de Salud (GI/OMS y por el Eyes-Hand-Feet (EHF. Los ex -pacientes fueron geocodificados por la dirección de residencia y los servicios de rehabilitación por la dirección de su sede. Se presentaron las frecuencias para el total y para los grupos grado 0, grado 1 y grado 2 del GI-OMS, considerándose las variables clínicas y sociodemográficas en el análisis descriptivo. Se utilizaron las pruebas t de Student, Chi-cuadrado (?2 o de Fisher, conforme apropiado, considerándose significativos p= 0,05. RESULTADOS: Cerca de 51,6% eran del sexo femenino, con promedio de edad de 54 años (de 15,7; 30,5% tenían menos de dos años de educación formal; 43,5% trabajaban y 26,9% estaban jubilados; la forma dimorfa predominó (39,9%. Las deficiencias evaluadas por el GI

Costo-beneficio de un programa preventivo y terapéutico para reducir la deficiencia de hierro en Argentina Cost-benefit of a prevention and treatment program to reduce iron deficiency in Argentina

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Ignacio Drake

2009-01-01

Full Text Available OBJETIVOS: Estimar los costos directos e indirectos de la deficiencia de hierro (DH y la anemia ferropénica (AF en Argentina y compararlos con los costos de un programa específico para su prevención y tratamiento. MÉTODOS: Análisis de escenario previo (ex ante de la relación costo-beneficio de un programa de prevención y tratamiento de la AF dirigido a todos los niños y las embarazadas pobres y sin cobertura social de Argentina. Las consecuencias económicas de la DH y la AF se estimaron a partir de los costos directos - gastos vinculados a la atención de un parto prematuro - e indirectos - pérdidas en la productividad futura de los niños por su peor desarrollo cognitivo debido a la DH y la menor productividad de los adultos por la AF - mediante la metodología específica desarrollada por The Micronutrient Initiative. Las intervenciones se definieron según las Guías de Práctica Clínica vigentes en Argentina y los costos de los componentes se tomaron de los precios de las licitaciones del Ministerio de Salud de la Nación. RESULTADOS: Cada US$ 1,00 invertido en un programa de prevención y tratamiento de la DH y la AF, con una cobertura de 90% de la población de lactantes y embarazadas pobres sin seguro explícito de salud, representaría un ahorro de US$ 33,40 por la prevención de las pérdidas económicas debidas a estas enfermedades. CONCLUSIÓN: Las intervenciones para enfrentar la DH no solo mejoran significativamente el estado de salud de la población, sino que representan un ahorro considerable de recursos.OBJECTIVES: To estimate the direct and indirect cost of iron deficiency (ID and iron-deficiency anemia (IDA in Argentina and compare it with the cost of a prevention and treatment program. METHODS: Analysis of a prior scenario to gage the relative cost-benefit of an IDA prevention and treatment program for all low-income children and expectant mothers without social coverage/benefits in Argentina. The economic

Relación de adiciones con trastornos alimentarios y deficiencias nutricionales

OpenAIRE

Ascacibar, Sabrina

2014-01-01

Los trastornos alimentarios no sólo causan cambios físicos graves, sino que también pueden estar relacionados con síndromes psiquiátricos, incluyendo abuso de drogas y alcohol. Fisiológicamente hay una asociación entre la alimentación y el consumo de sustancias psicoactivas, siendo el alcohol un inhibidor de la ingesta mientras que el cannabis estimula el apetito. El consumo de este tipo de sustancias genera deficiencias de calcio y magnesio causando síntomas fisiológicos y psicológicos. ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... en español Iron-deficiency anemia is a common type of anemia that occurs if you do not ... iron-deficiency anemia and help rule out other types of anemia. Treatment will explain treatment-related complications ...

Anemia (For Teens)

Science.gov (United States)

... Staying Safe Videos for Educators Search English Español Anemia KidsHealth / For Teens / Anemia What's in this article? ... Enough Iron Print en español Anemia What Is Anemia? Lots of teens are tired. With all the ...

Evaluación de la educación nutricional y un suplemento para prevenir la anemia durante la gestación.

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Beatriz Elena Parra

2005-06-01

Full Text Available Introducción. Las deficiencias de hierro y acido fólico son la causa de graves problemas de salud en la mujer gestante y en el niño, con implicaciones negativas para el desarrollo económico y social de los países. Objetivos. Evaluar los cambios de conocimientos sobre funciones, alimentos fuentes y biodisponibilidad del hierro y folatos, el consumo y la tolerancia de un suplemento y el comportamiento de los índices globulares en gestantes del programa prenatal de la Empresa Social del Estado Hospital Gilberto Mejía Mejía de Rionegro, Antioquia, Colombia, entre abril de 2002 y abril de 2003. Materiales y métodos. Estudio cuasi experimental en una muestra de 42 madres, seleccionada por conveniencia, con una confianza del 95%. La intervención fue un programa de educación nutricional y el suministro de un suplemento con 60 mg de hierro elemental, 400 J.g de acido fólico y 70 mg de vitamina C, elaborado para la investigación por el Laboratorio Profesional Farmacéutico, LAPROFF. El efecto de la intervención se midió en los cambios de conocimientos relacionados con las practicas que modifican la biodisponibilidad y el consumo de alimentos fuentes de estos nutrientes, en la tolerancia y la adherencia al suplemento y en la modificación de variables hematológicas: hemoglobina, hematocrito y ferritina. Resultados. Hubo cambios positivos de conocimientos sobre cómo mejorar las practicas alimentarias y la ingestión del suplemento; el 94,4% de las participantes no presentó anemia al finalizar la gestación. Conclusión. Estos resultados concuerdan con otros provenientes de poblaciones similares; se justifica implementar esta estrategia integrada en los programas de control prenatal de Colombia.

Fanconi anemia

Science.gov (United States)

... possibly given through a vein) to treat infections Blood transfusions to treat symptoms due to low blood counts ... have regular check-ups to screen for cancer. Alternative Names Fanconi's anemia; Anemia - Fanconi's Images Formed elements of blood References Bagby GC. Aplastic anemia and related bone ...

Hemolytic Anemia

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... worsen your condition or lead to complications. Hemolytic Anemia and Children Parents of children who have hemolytic anemia usually ... members, friends, and your child's classmates about hemolytic anemia. You also may want to tell your child's teachers or other caregivers about the condition. Let ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... anemia, your doctor may order the following blood tests to diagnose iron-deficiency anemia: Complete blood count (CBC) to ... than normal when viewed under a microscope. Different tests help your doctor diagnose iron-deficiency anemia. In iron-deficiency anemia, blood ...

Anemia como problema de saúde pública: uma realidade atual Anemia as a public health problem: the current situation

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Malaquias Batista Filho

2008-12-01

Full Text Available Em 1990, as Nações Unidas promoveram a Reunião de Cúpula de Nova Iorque, onde foram traçadas metas para o decênio vindouro, dentre as quais, a redução de um terço na prevalência das anemias nas mulheres em idade fértil. Porém, apesar de percentual modesto, indícios epidemiológicos apontam no sentido inverso, ou seja, indicam a crescente e grave ocorrência de anemia em diferentes regiões do mundo, inclusive no Brasil. Ao reunir esses informes, constata-se que a anemia continua, desde a antiguidade, a ser uma das entidades nosológicas mais prevalentes e difundidas nas populações humanas. A partir daí surge uma série de questionamentos ainda sem respostas em relação às reais prevalência e etiopatogenia do problema, ao grau de implantação e à efetividade das medidas de controle.In 1990, the United Nations held a World Summit in New York, in which goals for the upcoming decade were established. One of these goals was a one-third reduction in the prevalence of anemia among women at childbearing age. Despite this modest percentage, epidemiological indicators point to the opposite direction, indicating an increasing occurrence of anemia in different regions of the world, including in Brazil. These data show that anemia has continued since the antiquity to be one of the most prevalent and widespread diseases in human populations. Thus, a number of questions without answers arise regarding the actual prevalence and etiopathogenesis of the problem as well as with respect to the degree of implantation and the effectiveness of control measures.

Encuestas nacionales de ceguera y deficiencia visual evitables en Argentina, El Salvador, Honduras, Panamá, Perú y Uruguay

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Juan Carlos Silva

2014-10-01

Full Text Available OBJETIVO: Describir la justificación y metodología usadas en la Evaluación Rápida de Ceguera Evitable empleada para efectuar encuestas a nivel nacional entre 2011 y 2013 en Argentina, El Salvador, Honduras, Panamá, Perú y Uruguay. MÉTODOS: La encuesta se dirige a personas de 50 años o más, lo que reduce al mínimo los requisitos de tamaño de la muestra, que oscila entre 2 000 y 5 000 personas. Se emplean sistemas simples de muestreo y técnicas de examen; el análisis de datos es automático y no requiere de un experto en estadística. Es relativamente económica, ya que no toma mucho tiempo, no requiere equipos oftalmológicos costosos y puede ser llevada a cabo por el personal local. Los informes son generados mediante el propio programa informático de la evaluación. RESULTADOS: Los indicadores generados son la prevalencia de la ceguera y la deficiencia visual severa y moderada (discriminadas por causas evitables y cataratas; la prevalencia de afaquia o pseudofaquia; la cobertura de la cirugía de cataratas; el resultado visual de las cirugías de cataratas; las causas de resultados malos; las barreras de acceso a la cirugía de cataratas; y los indicadores de servicio de la cirugía de cataratas. Los resultados de cada una de las encuestas serán publicados de manera secuencial en números sucesivos de la revista, y en un artículo final de resumen se hará un análisis de los resultados en su conjunto y comparativo entre las encuestas y con aquellas publicadas anteriormente, que aportará un estado de la situación actual en ese grupo de países. CONCLUSIONES: La Evaluación Rápida de Ceguera Evitable es una metodología sólida, sencilla y económica para determinar la prevalencia de ceguera y deficiencia visual y la cobertura y calidad de los servicios de salud ocular, y representa una herramienta muy valiosa para medir el progreso de los programas de prevención de la ceguera y su impacto en la población.

What Is Aplastic Anemia?

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... Home / Anemia Aplastic Anemia Also known as What Is Aplastic anemia (a-PLAS-tik uh-NEE-me-uh) is ... heart, heart failure , infections, and bleeding. Severe aplastic anemia can even cause death. Overview Aplastic anemia is ...

Deficiencia de glucosa-6-fosfato deshidrogenasa en un paciente con síndrome de Down

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Francisco R. Cammarata Scalisi

2012-07-01

Full Text Available El síndrome de Down, es una alteración genética que ocurre cuando un individuo exhibe todo o una parte específica adicional del cromosoma 21 y es la entidad más frecuentemente asociada a retardo mental. La deficiencia de glucosa-6-fosfato deshidrogenasa, es el defecto enzimático más común en humanos y presenta patrón de herencia ligado al cromosoma X recesivo. Se debe a la mutación del gen G6PD, el cual causa diversos fenotipos bioquímicos y clínicos. Reportamos un caso de lactante menor masculino, evaluado en la Unidad de Genética Médica de la Universidad de Los Andes, con el diagnóstico de deficiencia de glucosa-6-fosfato deshidrogenasa con doble mutación A376G y G202A y síndrome de Down con estudio citogenético 47, XY, +21. Palabras clave:Síndrome de Down; deficiencia de glucosa-6-fosfato deshidrogenasa; G6PD; A37G6; G202A. Glucose-6-phosphate dehydrogenase deficiency in a patient with Down syndrome Abstract Down syndrome, is a genetic disorder that occurring when an individual exhibits all or part of an extra copy of chromosome 21 and the most common entity associated mental retardation. Glucose-6-phosphate dehydrogenase deficiency, is the most common human enzyme defect and has a X-linked recessive inheritance. Due to mutations in the G6PD gene, which cause many biochemical and clinical phenotypes. We reported a case of child male, evaluated in the Unit of Medical Genetics of the University of The Andes, with diagnosis of glucose-6-phosphate dehydrogenase deficiency with double mutation A376G and G202A and Down syndrome with cytogenetic study 47, XY, + 21.

Prevalencia de la deficiencia de glucosa - 6 - fosfato deshidrogenasa en donadores voluntarios de sangre que acuden a los hospitales nacionales Cayetano Heredia y Arzobispo Loayza: Lima - Perú

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Wilson Ruiz

1997-01-01

Full Text Available Objetivos: El presente trabajo tuvo como objetivo, conocer la Prevalencia de la deficiencia de la G-6-PDH, en la población masculina mestiza, aparentemente sana que acude a los Bancos de Sangre de los hospitales nacionales Cayetano Heredia (HNCH y Arzobispo Loayza (HNAL. Material y métodos: Se examinó 140 muestras de hemodonadores entre junio y julio, 60 (42.85% correspondieron al HNCH y 80 (57.15% al HNCH. Se aplicó un cuestionario a todos los donantes indagando por: raza en los ancestros y antecedentes patológicos compatibles con episodios de hemólisis enzimopática. En todas las muestras se empleó el método cualitativo de Brewer (tamizaje y posteriormente fueron sometidos a la prueba cuantitativa SIGMA. Resultados: Con el método de Brewer resultaron 9 casos positivos (6.42% de los cuales sólo uno resultó positivo con el método confirmatorio, lo cual da una prevalencia de 0.71%. La totalidad de los participantes fueron de raza mestiza, carecían de antecedentes importantes, las edades estuvieron comprometidas entre los 18 y 58 años y el hematocrito entre 40 y 48%. Conclusiones: Se confirma que la prevalencia de esta deficiencia, en nuestra población es bastante baja. (Rev Med Hered 1997; 8: 11-18.

Fatores associados a anemia por deficiência de ferro em crianças pré-escolares brasileiras Factors associated with iron deficiency anemia in Brazilian preschool children

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Carlos A. N. de Almeida

2004-06-01

Full Text Available OBJETIVO: Avaliar fatores determinantes de anemia e deficiência de ferro em crianças de duas creches da cidade de Pontal, sudeste do Brasil. MÉTODOS: Estudo transversal foi realizado avaliando-se 192 crianças com idades entre 12 e 72 meses. Dados pessoais (idade, sexo, uso de ferro medicamentoso, duração do aleitamento materno, tipo de parto, cuidados pré-natais, peso e estatura e dados socioeconômicos (número de co-habitantes, escolaridade dos pais e renda per capita familiar foram obtidos e correlacionados com hemoglobina, receptores de transferrina, ferritina e anemia ferropriva. RESULTADOS: A idade foi a variável mais afetada pelo estado nutricional de ferro, correlacionando-se com maiores valores de hemoglobina e ferritina e menores valores de receptor de transferrina, sendo que menos anemia ferropriva foi detectada quanto maior a idade. As outras variáveis estudadas não apresentaram correlação com o estado nutricional de ferro. CONCLUSÃO: Os dados sugerem que as estratégias de controle para essa população de crianças pré-escolares devem ser direcionadas especialmente para aquelas de menor idade.OBJECTIVE: To examine the determining factors of anemia and iron deficiency in children attending two day care centers in the town of Pontal, southeast of Brazil. METHODS: Cross-sectional study was conducted in 192 children aged 12 to 72 months. Personal data (age, sex, use of medicinal iron supplements, duration of breast-feeding, type of delivery, prenatal care, weight, and height, and socioeconomic data (number of co-inhabitants, parental schooling, and per capita family income were obtained and evaluated together with hemoglobin, serum transferrin receptor, ferritin, and iron deficiency anemia. RESULTS: Age was the variable that most affected iron nutritional status, with higher hemoglobin values, lower transferrin receptor concentrations, higher ferritin values and lower iron deficiency anemia being detected with increasing

Anemia do lactente: etiologia e prevalência Anemia in infancy: etiology and prevalence

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Maria Claret C.M. Hadler

2002-01-01

Full Text Available Objetivo: verificar a prevalência de anemia, anemia ferropriva e deficiência de ferro em lactentes, de unidade pública de saúde, no município de Goiânia, Brasil, analisar e correlacionar as variáveis bioquímicas e hematológicas. Métodos: realizou-se estudo transversal. De 120 mães entrevistadas, foram incluídos 110 lactentes de 6 a 12 meses de idade, a termo e não gemelares. Dados socioeconômicos e hematológicos foram obtidos. Colheu-se sangue venoso dos lactentes em jejum para realização do hemograma completo por contagem eletrônica, ferro sérico, ferritina sérica e proteína C-reativa, os quais foram utilizados na avaliação da etiologia ferropriva nos anêmicos. Crianças com hemoglobina Objective: To verify the prevalence of anemia, iron deficiency anemia and iron deficiency in infants, at a Public Health Unit in the city of Goiânia - Brazil; to analyze and to correlate the hematologic and biochemical variables. Methods: A cross-sectional study was carried out. One hundred and ten full-term infants of the 120 mothers interviewed were included. The infants aged between six and twelve months and there were not twins. Socioeconomic and hematologic data was obtained. Venous blood was taken from fasting infants in order to carry out a complete hemogram through electronic cell counting, serum iron, serum ferritin and C-reactive protein, which were used in the evaluation of the etiology of iron deficiency in the anemic infants. Children with hemoglobin < 11g/dL were considered anemic. Results: The prevalence of anemia was 60.9%. In the diagnosis of the iron deficiency etiology in infants without an inflammation process, when considering the alteration of hemoglobin plus two more indices among mean corpuscular volume (MCV or mean corpuscular hemoglobin (MCH or serum ferritin or serum iron, the prevalence of the iron deficiency was 87%. Nevertheless, when red cell distribution width (RDW was included in the indices, the

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... Blood Transfusion Heart-Healthy Lifestyle Changes Heart Failure Hemolytic Anemia Hemophilia Pernicious Anemia Restless Legs Syndrome Von Willebrand Disease Other Resources NHLBI resources Your Guide to Anemia [ ...

What Is Anemia?

Science.gov (United States)

... Intramural Research Home / Anemia Anemia Also known as Iron-poor blood , Low blood , ... you or your child diagnosed with Diamond-Blackfan anemia? The registry is collecting information from people with ...

Anemia

Science.gov (United States)

... child might have anemia. They will do a physical exam and review your health history and symptoms. To diagnose anemia, your doctor ... and Wellness Staying Healthy Healthy Living Travel Occupational Health First Aid and ... Pets and Animals myhealthfinder Food and Nutrition Healthy Food ...

Anemia em menores de seis anos: estudo de base populacional em Pelotas, RS Anemia in children under six: population-based study in Pelotas, Southern Brazil

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Maria Cecília Formoso Assunção

2007-06-01

Full Text Available OBJETIVO: Analisar a prevalência de anemia em crianças menores de seis anos, em uma amostra probabilística de área urbana. MÉTODOS: Foi realizado estudo com crianças de zero a cinco anos de idade, na cidade de Pelotas, RS, em 2004. Foram coletadas informações sobre características demográficas, socioeconômicas, antropométricas, de morbidade e sobre alimentação, por meio de questionário aplicado às mães ou responsáveis. As crianças foram pesadas e medidas. A concentração de hemoglobina foi medida com hemoglobinômetro portátil, HemoCue e anemia foi definida como valores de hemoglobina OBJECTIVE: To assess the prevalence of anemia among children under six years of age in a probabilistic sample from an urban area. METHODS: A study was conducted comprising children aged zero to five years in the city of Pelotas, Southern Brazil, in 2004. Data were collected on demographic, socioeconomic, and anthropometric characteristics, morbidity and nutrition using a questionnaire applied to the mothers and guardians. Children's weight and height measurements were obtained. Hemoglobin concentration was measured using the HemoCue portable hemoglobinometer and anemia was defined as hemoglobin <11 g/dL. The association between anemia and predictors was expressed as prevalence ratio. Multivariate analysis was carried out using Poisson regression following a conceptual model and taking into account the study design effect. RESULTS: There were identified 534 children and total losses and refusals were 27 (5.1%. The prevalence of anemia was 30.2% (95% CI 23.5%;37.0%. In the multivariate analysis, only age and family income remained significantly associated with anemia. CONCLUSIONS: Anemia was largely socially determined in the population studied. Interventions aiming at reducing anemia should be developed to lessen this condition in the short run targeting disadvantaged populations.

LA ATENCIÓN ODONTOLÓGICA DEL PACIENTE CON DEFICIENCIA AUDITIVA

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Alejandro Joaquín Encina Tutuy

2012-07-01

Full Text Available La sordera acarrea consecuencias personales y sociales, como ser, dificultades y/o conflictos a la hora de recibir atención de salud. La comunicación juega un rol importante en la relación entre el paciente y el profesional. Si bien las manifestaciones bucales que se reportan son similares a las de los individuos normales, el odontólogo debe conocer y poseer las estrategias y herramientas necesarias para la atención y alcanzar con éxito los objetivos propuestos de tratamiento. El objetivo de este artículo de revisión es poner de relieve ciertas consideraciones a tener en cuenta al momento de atender un paciente con deficiencias auditivas.

LA ATENCIÓN ODONTOLÓGICA DEL PACIENTE CON DEFICIENCIA AUDITIVA

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Alejandro Joaquín Encina Tutuy

2012-12-01

Full Text Available La sordera acarrea consecuencias personales y sociales, como ser, dificultades y/o conflictos a la hora de recibir atención de salud. La comunicación juega un rol importante en la relación entre el paciente y el profesional. Si bien las manifestaciones bucales que se reportan son similares a las de los individuos normales, el odontólogo debe conocer y poseer las estrategias y herramientas necesarias para la atención y alcanzar con éxito los objetivos propuestos de tratamiento. El objetivo de este artículo de revisión es poner de relieve ciertas consideraciones a tener en cuenta al momento de atender un paciente con deficiencias auditivas.

Anemia and Pregnancy

Science.gov (United States)

... Advocacy Toolkit Home For Patients Blood Disorders Anemia Anemia and Pregnancy Your body goes through significant changes ... becoming anemic. back to top Is Pregnancy-Related Anemia Preventable? Good nutrition is the best way to ...

Factores de riesgo de la anemia ferropénica en lactantes del policlínico “Dr. Gustavo Aldereguía Lima”

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Eldir Diéguez Velázquez

2015-12-01

Full Text Available La incidencia de lactantes con anemia ferropénica, a pesar de existir un programa de prevención de esta anemia en estas edades, sobre todo en el área de salud del policlínico “Dr. Gustavo Aldereguía Lima”, ha sido la motivación de un estudio, con el objetivo de determinar los factores de riesgo que guardan asociación causal con esta problemática. La investigación se llevó a cabo durante el período de enero de 2010 a junio de 2012; analítica de casos y controles. El grupo de enfermos estuvo formado por 25 pacientes diagnosticados clínicamente y por estudios hematológicos. El grupo de control estuvo constituido por 50 niños no afectados, escogidos al azar. Los resultados se expusieron en tablas de contingencia de 2 x 2, que permitieron determinar los antecedentes prenatales, natales y postnatales,  favorecedores de anemia.

Defectos eritrocíticos y densidad de la parasitemia en pacientes con malaria por Plasmodium falciparum en Buenaventura, Colombia Erythrocyte defects and parasitemia density in patients with Plasmodium falciparum malaria in Buenaventura, Colombia

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Martha Moyano

2005-07-01

Full Text Available OBJETIVOS: Determinar la prevalencia de algunos defectos eritrocíticos y evaluar su relación con la densidad de la parasitemia en personas con diagnóstico de malaria (paludismo por Plasmodium falciparum en una población del Pacífico colombiano. MÉTODOS: Se realizó un estudio de prevalencia en 242 personas con malaria por P. falciparum que consultaron al Programa de Enfermedades Tropicales en la ciudad de Buenaventura, Colombia. Se midieron los niveles de parasitemia y se determinó la presencia de defectos eritrocíticos congénitos (deficiencia de glucosa-6-fosfato deshidrogenasa [G6PD] y presencia de hemoglobinas anormales y de talasemias y de otros factores potencialmente relacionados con los niveles de parasitemia. RESULTADOS: La prevalencia obtenida de defectos eritrocíticos fue de 26,4% (IC95% 21,0 a 32,5, similar a la hallada en estudios realizados antes en la misma zona. En los modelos de regresión múltiple, las personas con drepanocitosis o deficiencia total de la G6PD presentaron una menor densidad de parasitemia que las personas sin defecto, y el riesgo de parasitemias altas fue menor en estas personas después de ajustes respecto a otras variables de interés (razón de posibilidades [odds ratio, RP]: 0,30 y 0,72, respectivamente. CONCLUSIONES: Los resultados confirman una alta prevalencia de defectos eritrocíticos en el Pacífico colombiano, en una población con características étnicas similares a las de algunas poblaciones del África Occidental, y aportan información en favor de la existencia de resistencia innata a la malaria en personas portadoras de hemoglobina AS o con deficiencia de la G6PD.OBJECTIVES: To determine the prevalence of some erythrocyte defects and to evaluate the relation that that has with parasitemia density in individuals diagnosed with Plasmodium falciparum malaria in a population in the Pacific coastal region of Colombia. METHODS: This prevalence study was carried out with 242 persons with P

ANEMIA DAN ANEMIA GIZI BESI PADA KEHAMILAN: HUBUNGANNYA DENGAN ASUPAN PROTEIN DAN ZAT GIZI MIKRO

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Nur Handayani Utami

2015-03-01

Full Text Available Anemia masih menjadi permasalahan kesehatan pada wanita hamil. Zat besi dianggap sebagai salah satu zat gizi mikro yang berperan terhadap terjadinya anemia. Kekurangan gizi besi dalam tingkat lanjut dapat menyebabkan anemia, yang disebut sebagai anemia gizi besi. Tujuan studi ini adalah untuk menganalisis perbedaan antara asupan protein dan gizi mikro serta menghitung odd ratio (OR kejadian anemia dan anemia gizi besi akibat asupan protein dan gizi mikro pada wanita hamil di lokasi studi. Analisis ini merupakan analisa dari data studi kohor Tumbuh Kembang anak pada tahun pertama, yang dilaksanakan di Kelurahan Kebon Kalapa dan Ciwaringin, Kota Bogor yang dianalisa menggunakan disainkasus kontrol. Sebanyak 47 ibu hamil menjadi sampel dalam analisa ini. Kategori untuk anemia yaitu apabila kadar hemoglobin (Hb ibu hamil ≤11 g/dL. Kekurangan gizi besi dikategorikan apabila kadar serum transferrin reseptor (sTfR diatas 4.4 mg/L. Sedangkan Anemia Gizi Besi dikategorikan apabila memiliki kadar Hb < 11 g/dL dan sTfr > 4.4 mg/L. Tes one way anova digunakan untuk menganalisa adanya perbedaan asupan energi, protein dan zat gizi mikro antara ibu hamil yang mengalami anemia, anemia gizi besi maupun yang normal. Odd ratio dianalisa dengan menggunakan uji chi square. Nilai signifikan ditentukan apabila nilai p value < 0.05 dan perhitungan OR> 1. 27.7% dari ibu hamil di lokasi studi mengalami anemia, 14.9% tergolong dalam anemia ringan, 10.6% anemia sedang dan 2.1% anemia berat. Anemia gizi besi dialami oleh 17% dari wanita hamil. Terdapat hubungan yang signifikan antara keparahan anemia dan terjadinya anemia gizi besi. Tidak ditemukan perbedaan antara asupan protein, besi, folate dan zink pada wanita yang mengalami anemia, anemia gizi besi maupun yang normal. Akan tetapi terdapat kecenderungan bahwa asupan zat besi dan seng pada ibu yang anemia dan anemia gizi besi lebih rendah daripada ibu yang normal. Anemia masih menjadi permasalahan kesehatan pada ibu

Inborn anemias in mice

International Nuclear Information System (INIS)

Bernstein, S.E.; Barker, J.E.; Russell, E.S.

1981-06-01

hereditary anemias of mice have been the chief objects of investigation. At present under study are four macrocytic anemias, five hemolytic anemias, nonhemolytic microcytic anemia, transitory siderocytic anemia, sex-linked iron-transport anemia, an α-thalassemia, and a new target-cell anemia. Each of these blood dyscrasias is caused by the action of a unique mutant gene, which determines the structure of different intracellular molecules, and thus controls a different metabolic process. Thus our wide range of different hereditary anemias has considerable potential for uncovering many different aspects of hemopoietic homeostatic mechanisms in the mouse. Each anemia is studied through: (a) characterization of peripheral blood values, (b) determinations of radiosensitivity under a variety of conditions, (c) measurements of iron metabolism and heme synthesis, (d) histological and biochemical study of blood-forming tissue, (e) functional tests of the stem cell component, (f) examination of responses to erythroid stimuli, and (g) transplantation of tissue between individuals of differently affected genotypes

Anemia em escolares da primeira série do ensino fundamental da rede pública de Maceió, Alagoas, Brasil Anemia in public school first graders in the city of Maceió, Alagoas, Brazil

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Célia Dias dos Santos

2002-12-01

Full Text Available Realizou-se um estudo transversal com amostra probabilística de 426 alunos de 6 a 10 anos, da 1ª série do ensino fundamental das escolas públicas de Maceió, Alagoas, Brasil. O objetivo foi avaliar a prevalência da anemia e sua associação com o retardo de crescimento. Os dados foram coletados entre maio e julho de 2000. O sangue foi colhido por venipuntura e a dosagem de hemoglobina (Hb foi realizada pelo contador Coulter STKS. Classificou-se a anemia por dois critérios estabelecidos pela Organização Mundial da Saúde: Hb A cross-sectional study was conducted in a representative sample of 426 randomly selected first graders (ages 6 to 10 years from public schools in Maceió, State of Alagoas, Brazil. The aim was to determine the prevalence of anemia, as well as its association with growth retardation. Data were collected from May to July 2000, and determination of hemoglobin (HGB employed an STKS Coulter counter. Two cut-off points were used to classify anemia, both established by the World Health Organization: HGB < 11.5g/dl and HGB < 12.0g/dl. The indicators height/age (H/A, weight/age (W/A, and weight/height (W/H below -2.0 standard deviations from the NCHS reference were diagnosed as growth retardation. Prevalence of anemia was 9.9% when HGB < 11.5g/dl was used, and 25.4% when the cut-off point was HGB < 12.0g/dl. Growth retardation was detected in 6.2% of children according to H/A, 4.0% for W/A, and 3.0% for W/H. There was no statistically significant association between the variables in the study. These findings confirm results of previous surveys where prevalence of anemia was much higher than that of growth retardation. The severe consequences of anemia in this age group justify the implementation of broad public policies to overcome this nutritional deficiency.

Anemia Due to Excessive Bleeding

Science.gov (United States)

... Hemolytic Anemia Hemoglobin C, S-C, and E Diseases Iron Deficiency Anemia Sickle Cell Disease Thalassemias Vitamin Deficiency Anemia (See ... Hemolytic Anemia Hemoglobin C, S-C, and E Diseases Iron Deficiency Anemia Sickle Cell Disease Thalassemias Vitamin Deficiency Anemia NOTE: ...

From Bad to Worse: Anemia on Admission and Hospital-Acquired Anemia.

Science.gov (United States)

Koch, Colleen G; Li, Liang; Sun, Zhiyuan; Hixson, Eric D; Tang, Anne S; Phillips, Shannon C; Blackstone, Eugene H; Henderson, J Michael

2017-12-01

Anemia at hospitalization is often treated as an accompaniment to an underlying illness, without active investigation, despite its association with morbidity. Development of hospital-acquired anemia (HAA) has also been associated with increased risk for poor outcomes. Together, they may further heighten morbidity risk from bad to worse. The aims of this study were to (1) examine mortality, length of stay, and total charges in patients with present-on-admission (POA) anemia and (2) determine whether these are exacerbated by development of HAA. In this cohort investigation, from January 1, 2009, to August 31, 2011, a total of 44,483 patients with POA anemia were admitted to a single health system compared with a reference group of 48,640 without POA anemia or HAA. Data sources included the University HealthSystem Consortium database and electronic medical records. Risk-adjustment methods included logistic and linear regression models for mortality, length of stay, and total charges. Present-on-admission anemia was defined by administrative coding. Hospital-acquired anemia was determined by changes in hemoglobin values from the electronic medical record. Approximately one-half of the patients experienced worsening of anemia with development of HAA. Risk for death and resource use increased with increasing severity of HAA. Those who developed severe HAA had 2-fold greater odds for death; that is, mild POA anemia with development of severe HAA resulted in greater mortality (odds ratio, 2.57; 95% confidence interval, 2.08-3.18; P < 0.001), increased length of stay (2.23; 2.16-2.31; P < 0.001), and higher charges (2.09; 2.03-2.15; P < 0.001). Present-on-admission anemia is associated with increased mortality and resource use. This risk is further increased from bad to worse when patients develop HAA. Efforts to address POA anemia and HAA deserve attention.

Your Guide to Anemia

Science.gov (United States)

... Inherited Causes l Folate or iron deficiency l Fanconi anemia from poor diet l Shwachman-Diamond l Demand ... cells, leading to aplastic anemia. These conditions include Fanconi anemia, Shwachman-Diamond syndrome, dyskeratosis congenita, Diamond- Blackfan anemia, ...

Iron-Deficiency Anemia

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Full Text Available ... to moderate iron-deficiency anemia, or red blood cell transfusion for severe iron-deficiency anemia. You may ... body needs iron to make healthy red blood cells. Iron-deficiency anemia usually develops over time because ...

Iron-Deficiency Anemia

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Full Text Available ... view the colon directly. What if my doctor thinks something else is causing my iron-deficiency anemia? ... deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. Treating anemia in premature ...

Iron-Deficiency Anemia

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Full Text Available ... you are diagnosed with iron-deficiency anemia. Risk Factors You may have an increased risk for iron- ... iron-deficiency anemia if you have certain risk factors , including pregnancy. To prevent iron-deficiency anemia, your ...

Iron-Deficiency Anemia

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Full Text Available ... detect signs of iron-deficiency anemia and help rule out other types of anemia. Treatment will explain ... your blood. More testing may be needed to rule out other types of anemia. Tests for gastrointestinal ...

About Anemia (For Kids)

Science.gov (United States)

... Safe Videos for Educators Search English Español About Anemia KidsHealth / For Kids / About Anemia What's in this ... to every cell in your body. What Is Anemia? Anemia happens when a person doesn't have ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... for iron-deficiency anemia if you have certain risk factors , including pregnancy. To prevent iron-deficiency anemia, your doctor may recommend you eat heart-healthy foods or control other conditions that can cause iron-deficiency anemia. ...

Iron-Deficiency Anemia

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Full Text Available ... Home / < Back To Health Topics / Iron-Deficiency Anemia Iron-Deficiency Anemia Also known as Leer en español ... bleeding Consuming less than recommended daily amounts of iron Iron-deficiency anemia can be caused by getting ...

Iron-Deficiency Anemia

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Full Text Available ... may require intravenous (IV) iron therapy or a blood transfusion . Iron supplements Your doctor may recommend that you ... Anemia Aplastic Anemia Arrhythmia Blood Donation Blood Tests Blood Transfusion Heart-Healthy Lifestyle Changes Heart Failure Hemolytic Anemia ...

Iron-Deficiency Anemia

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Full Text Available ... Iron-Deficiency Anemia Iron-Deficiency Anemia Also known as Leer en español Iron-deficiency anemia is a ... address the cause of your iron deficiency, such as any underlying bleeding. If undiagnosed or untreated, iron- ...

Iron-Deficiency Anemia

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Full Text Available ... Medicine (TOPMed) Program Non-NHLBI resources Anemia (National Library of Medicine, MedlinePlus) Anemia in Chronic Kidney Disease ( ... Supplement Fact Sheet (NIH) Iron-Deficiency Anemia (National Library of Medicine, MedlinePlus) Building 31 31 Center Drive ...

Modificaciones funcionales ventilatorias en pacientes con anemia drepanocítica y antecedentes de síndrome torácico agudo Respiratory functional changes in patients with sickle cell anemia and history of acute chest synd

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José René Mesa Cuervo

2002-08-01

Full Text Available Se realizó un estudio descriptivo prospectivo para evaluar la función ventilatoria en pacientes con anemia drepanocítica (AD y antecedentes de síndrome torácico agudo (STA atendidos en consulta externa del Instituto de Hematología e Inmunología de septiembre de 1999 a septiembre del 2000. El universo de estudio se dividió en 2 grupos: el primero constituido por 36 pacientes con el diagnóstico de AD y antecedente de STA, y el segundo por 17, con una distribución por edades y sexos similar al anterior con AD, pero sin el antecedente de STA. A todos los pacientes seleccionados se les realizaron las pruebas funcionales ventilatorias (PFV siguiendo criterios internacionales. La disfunción ventilatoria restrictiva se observó en todos los pacientes con AD independiente del antecedente de STA, sin embargo, el antecedente de 2 y más STA mostró los mayores porcentajes. La edad y el sexo no influyeron en los resultados espirométicosA prospective descriptive study was made to evaluate the respiratory function in patients with sickle cell anemia and history of acute chest syndrome seen at the outpatient service of the Institute of Hematology and Immunology from September 1999 to September 2000. The universe of study was divided into 2 groups: the first was made up of 36 patients diagnosed with sickle cell anemia and history of acute thoracic syndrome; and the second included 17 patients with sickle cell anemia, distributed by age and sex in a similar way as in the first one, but without history of acute chest syndrome. All the selected patients were applied the respiratory function tests according to the international criteria. Restrictive respiratory dysfunction was observed in all patients with sickle cell anemia regardless of their history of acute chest syndrome; however, the history of two or more syndromes showed the highest percentages. Age and sex did not influence the results

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... anemia if you have certain risk factors , including pregnancy. To prevent iron-deficiency anemia, your doctor may recommend you eat heart-healthy foods or control other conditions that can cause iron-deficiency anemia. Blood tests to screen for ...

Iron-Deficiency Anemia

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Full Text Available ... exploring about iron-deficiency anemia. Read more New treatments for disorders that lead to iron-deficiency anemia. We are ... and other pathways. This could help develop new therapies for conditions that ... behavior, thinking, and mood during adolescence. Treating anemia in ...

Iron deficiency anemia

Science.gov (United States)

Anemia - iron deficiency ... iron from old red blood cells. Iron deficiency anemia develops when your body's iron stores run low. ... You may have no symptoms if the anemia is mild. Most of the time, ... slowly. Symptoms may include: Feeling weak or tired more often ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... Topics News & Resources Intramural Research Home / < Back To Health Topics / Iron-Deficiency Anemia Iron-Deficiency Anemia Also known as Leer ... and symptoms as well as complications from iron-deficiency anemia. Research for Your Health The NHLBI is part of the U.S. Department ...

Auditoría interna y deficiencias de la información financiera en el sector bancario español

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Ester Gras-Gil

2015-07-01

Full Text Available La auditoría interna (AI ha cobrado un papel trascendental en la regulación sobre el gobierno corporativo. En este sentido, se le otorga un papel fundamental en la calidad de la información financiera como supervisora de la fiabilidad de la misma. El presente trabajo analiza si la estructura y las características de la AI afectan a las deficiencias de la información contable. Para ello hemos analizado los departamentos de AI de las entidades financieras españolas, utilizando una muestra de 47 entidades, para el periodo 2006-2010. Nuestros resultados muestran que existen unas características de la AI que contribuyen a que la entidad presente menos deficiencias de la información financiera: la formación de los auditores internos y la independencia de la AI.

Anemia in Chronic Kidney Disease

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... artérielle Heart Disease Mineral & Bone Disorder Anemia in Chronic Kidney Disease What is anemia? Anemia is a condition in ... as they should. How is anemia related to chronic kidney disease? Anemia commonly occurs in people with chronic kidney ...

Anemia in Chronic Kidney Disease

Science.gov (United States)

... Cysts Solitary Kidney Your Kidneys & How They Work Anemia in Chronic Kidney Disease What is anemia? Anemia is a condition in which the body ... function as well as they should. How is anemia related to chronic kidney disease? Anemia commonly occurs ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... Topics section only, or the News and Resources section. NHLBI Entire Site NHLBI Entire Site Health ... español Iron-deficiency anemia is a common type of anemia that occurs if you do not have enough iron in your body. People with mild or moderate iron-deficiency anemia ...

Predictors of anemia in preschool children: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project

Science.gov (United States)

Aaron, Grant J; Huang, Jin; Varadhan, Ravi; Temple, Victor; Rayco-Solon, Pura; Macdonald, Barbara

2017-01-01

Background: A lack of information on the etiology of anemia has hampered the design and monitoring of anemia-control efforts. Objective: We aimed to evaluate predictors of anemia in preschool children (PSC) (age range: 6–59 mo) by country and infection-burden category. Design: Cross-sectional data from 16 surveys (n = 29,293) from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project were analyzed separately and pooled by category of infection burden. We assessed relations between anemia (hemoglobin concentration anemia (hemoglobin concentration anemia with concomitant iron deficiency (defined as an inflammation-adjusted ferritin concentration anemia in >50% of surveys. Associations between breastfeeding and anemia were attenuated by controlling for child age, which was negatively associated with anemia. The most consistent predictors of severe anemia were malaria, poor sanitation, and underweight. In multivariable pooled models, child age, iron deficiency, and stunting independently predicted anemia and severe anemia. Inflammation was generally associated with anemia in the high- and very high–infection groups but not in the low- and medium-infection groups. In PSC with anemia, 50%, 30%, 55%, and 58% of children had concomitant iron deficiency in low-, medium-, high-, and very high–infection categories, respectively. Conclusions: Although causal inference is limited by cross-sectional survey data, results suggest anemia-control programs should address both iron deficiency and infections. The relative importance of factors that are associated with anemia varies by setting, and thus, country-specific data are needed to guide programs. PMID:28615260

Aplastic Anemia

Science.gov (United States)

Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make ... blood cells. There are different types, including Fanconi anemia. Causes include Toxic substances, such as pesticides, arsenic, ...

Índice de anisocitose eritrocitária (RDW: diferenciação das anemias microcíticas e hipocrômicas Red blood cell distribution width (RDW: differentiation of microcytic and hypochromic anemias

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Januária F. Matos

2008-04-01

Full Text Available A anemia ferropriva, talassemia menor e anemia de doença crônica são as anemias microcíticas e hipocrômicas mais comuns em nosso meio. O diagnóstico diferencial das referidas anemias é de grande importância clínica; contudo, muitas vezes é complexo em virtude de concomitância de doenças, além de demandar tempo e apresentar custos significativos. Com o propósito de conferir maior simplicidade e eficiência ao diagnóstico diferencial destas anemias, o uso de índices derivados de modernos contadores automáticos tem sido sugerido. Entre estes, pode ser citado o índice de anisocitose eritrocitária (RDW, que indica o grau de variabilidade do tamanho das hemácias. Neste estudo, o poder de discriminação deste índice quanto ao tipo de anemia microcítica e hipocrômica foi avaliado em um grupo de 159 pacientes sabidamente portadores de um quadro de anemia causado por deficiência de ferro, beta talassemia menor ou uma anemia de doença crônica. Não foi observada diferença significativa para o RDW entre os três grupos de anemias microcíticas, indicando não ser este índice uma ferramenta útil para a diferenciação entre anemia ferropriva, beta talassemia menor e anemia de doença crônica.Iron deficiency anemia, the thalassemia trait and chronic disease anemia are the most common microcytic and hypochromic anemias in the Brazilian population. Differential diagnosis of these anemias is of great clinical importance however, frequently, it is complex due to coexistence of diseases, as well as being time consuming and expensive. In order to simplify and increase efficiently of checking the differential diagnoses of these anemias, the use of indexes derived from modern blood cell counters has been suggested. Among them, is the index called red blood cell distribution width which indicates the variability in red blood cell size. In this study, the discriminative power of the red blood cell distribution width in differentiating

Efecto de la deficiencia de N, P, K, Ca, Mg y B en componentes de producción y calidad de la uchuva (Physalis peruviana L.

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Martínez Fabio Ernesto

2008-12-01

Full Text Available

A pesar de ser la uchuva el segundo fruto de exportación más importante de Colombia, existe poca información sobre el efecto de una nutrición deficiente en la producción y calidad de sus frutos. Plantas de uchuva, propagadas por semilla, se sembraron en sustrato arena cuarcítica en materas de plástico (25 L y se mantuvieron durante 135 días en condiciones de invernadero de plástico en Bogotá. Las deficiencias nutricionales se indujeron a través de soluciones nutritivas, usando el método del elemento faltante y empleando un diseño completamente al azar con 8 tratamientos y 5 repeticiones: 1. testigo con fertilización completa; 2. fertilización completa -N; 3. -P; 4. -K; 5. -Ca; 6. -Mg; 7. -B y 8. solo agua potable. En producción se evaluó el diámetro, peso y número de los frutos, el rendimiento y el peso seco de frutos y cáliz. Para la calidad del fruto se consideraron las variables sólidos solubles totales (SST, acidez total titulable (ATT y el pH. El tratamiento -B afectó negativamente las variables de producción como tamaño, peso fresco y seco del fruto y masa seca del cáliz. Las plantas deficientes en N y K redujeron el peso fresco y seco de sus frutos considerablemente. Comparados con el testigo, todos los otros tratamientos disminuyeron el número de frutos y el rendimiento por planta, los -B, -N y -K disminuyeron en más del 90% la cantidad de frutos producidos y el rendimiento, y el tratamiento -P en un 50%. El contenido de SST en frutos se redujo en plantas deficientes de B, mientras la ATT se incrementó en aquellas con deficiencia de P, comparada con la de -Ca.

Mouse models of Fanconi anemia

International Nuclear Information System (INIS)

Parmar, Kalindi; D'Andrea, Alan; Niedernhofer, Laura J.

2009-01-01

Fanconi anemia is a rare inherited disease characterized by congenital anomalies, growth retardation, aplastic anemia and an increased risk of acute myeloid leukemia and squamous cell carcinomas. The disease is caused by mutation in genes encoding proteins required for the Fanconi anemia pathway, a response mechanism to replicative stress, including that caused by genotoxins that cause DNA interstrand crosslinks. Defects in the Fanconi anemia pathway lead to genomic instability and apoptosis of proliferating cells. To date, 13 complementation groups of Fanconi anemia were identified. Five of these genes have been deleted or mutated in the mouse, as well as a sixth key regulatory gene, to create mouse models of Fanconi anemia. This review summarizes the phenotype of each of the Fanconi anemia mouse models and highlights how genetic and interventional studies using the strains have yielded novel insight into therapeutic strategies for Fanconi anemia and into how the Fanconi anemia pathway protects against genomic instability.

Mouse models of Fanconi anemia

Energy Technology Data Exchange (ETDEWEB)

Parmar, Kalindi; D' Andrea, Alan [Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115 (United States); Niedernhofer, Laura J., E-mail: niedernhoferl@upmc.edu [Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine and Cancer Institute, 5117 Centre Avenue, Hillman Cancer Center, Research Pavilion 2.6, Pittsburgh, PA 15213-1863 (United States)

2009-07-31

Fanconi anemia is a rare inherited disease characterized by congenital anomalies, growth retardation, aplastic anemia and an increased risk of acute myeloid leukemia and squamous cell carcinomas. The disease is caused by mutation in genes encoding proteins required for the Fanconi anemia pathway, a response mechanism to replicative stress, including that caused by genotoxins that cause DNA interstrand crosslinks. Defects in the Fanconi anemia pathway lead to genomic instability and apoptosis of proliferating cells. To date, 13 complementation groups of Fanconi anemia were identified. Five of these genes have been deleted or mutated in the mouse, as well as a sixth key regulatory gene, to create mouse models of Fanconi anemia. This review summarizes the phenotype of each of the Fanconi anemia mouse models and highlights how genetic and interventional studies using the strains have yielded novel insight into therapeutic strategies for Fanconi anemia and into how the Fanconi anemia pathway protects against genomic instability.

Severe Aplastic Anemia (SAA)

Science.gov (United States)

... page Print this page My Cart Severe aplastic anemia (SAA) Severe aplastic anemia (SAA) is a disease ... leukemia (ALL) Other diseases What is severe aplastic anemia (SAA)? SAA is a bone marrow disease. The ...

Fanconi's Anemia Effect or Sickle Cell Anemia Effect: That is the Question.

Science.gov (United States)

Unal, Sule; Chui, David H K; Gumruk, Fatma

2015-01-01

A 16-year-old boy who was diagnosed to have sickle cell anemia was referred to our center. The parental consanguinity, growth retardation and dysmorphic features prompted a search for possible Fanconi's Anemia (FA). The diepoxybutane (DEB) test was positive, confirming FA. The interaction of both diseases might account for his relatively mild phenotype in terms of both sickle cell anemia (or Hb S, HBB: c.20A > T) and FA. The high Hb F level that might be related to concomitant FA, may have caused a milder phenotype of sickle cell anemia, whereas nitric oxide (NO) depletion as a consequence of sickle cell anemia, may have caused a delay in the bone marrow failure of FA.

The Prevalence of Anemia and Moderate-Severe Anemia in the US Population (NHANES 2003-2012)

Science.gov (United States)

2016-01-01

Since anemia is associated with poor health outcomes, the prevalence of anemia is a significant public health indicator. Even though anemia is primarily caused by iron deficiency, low oxygen-carrying capacity may result from other conditions such as chronic diseases, which remain a relevant health concern in the United States. However, studies examining current rates of anemia in the total US population and in more specific subgroups are limited. Data from five National Health and Nutrition Examination Surveys (NHANES) from 2003 to 2012 were analyzed to assess two outcomes: anemia and moderate-severe anemia, which were based upon serum hemoglobin levels (Hb) as per World Health Organization (WHO) definitions. Statistical analysis using SAS examined temporal trends and the prevalence of anemia among sexes, age groups, and races/ethnicities. The study estimated that an average of 5.6% of the U.S. population met the criteria for anemia and 1.5% for moderate-severe anemia during this 10-year period. High-risk groups such as pregnant women, elderly persons, women of reproductive age, non-Hispanic blacks, and Hispanics were identified, and relationships between multiple risk factors were examined. Rates of anemia in men increased monotonically with age, while that of women increased bimodally with peaks in age group 40–49 years and 80–85 years. The effect of risk factors was observed to compound. For instance, the prevalence of anemia in black women aged 80–85 years was 35.6%, 6.4 times higher than the population average. Moreover, anemia is a growing problem because of the increased prevalence of anemia (4.0% to 7.1%) and moderate-severe anemia (1.0% to 1.9%), which nearly doubled from 2003–2004 to 2011–2012. Thus, these results augment the current knowledge on anemia prevalence, severity, and distribution among subgroups in the US and raised anemia as an issue that requires urgent public health intervention. PMID:27846276

Fanconi Anemia Research Fund

Science.gov (United States)

... Support Publications Fundraising News What is the Fanconi Anemia Research Fund? Fanconi anemia is an inherited disease that can lead to ... population. Lynn and Dave Frohnmayer started the Fanconi Anemia Research Fund, in 1989 to find effective treatments ...

Anemia crônica e glomerulopatia secundárias à Doença de Depósito das Cadeias Leves Chronic anemia and glomerulopathy secondary to Light-chain Deposition Disease

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Ítala P. Silveira

2004-01-01

Full Text Available Os autores relatam o caso de uma paciente do sexo feminino, 65 anos de idade, internada com anemia de longa evolução que se associou posteriormente a uma glomerulopatia manifestada por proteinúria, cilindrúria e perda de função renal. As cadeias leves no plasma e na urina estavam elevadas, sobretudo a fração kappa e uma biópsia renal estudada por imunofluorescência e microscopia eletrônica confirmou o diagnóstico de Doença de Depósito das Cadeias Leves. A nefropatia de cadeia leve ocorre pela superprodução de cadeia leve de imunoglobulina produzida por linfócitos B com deposição nas membranas tubulares e no glomérulo.The authors present a case of a 65-year-old female patient, with chronic anemia associated with glomerulopathy manifested as proteinuria, cylindruria and renal failure. There were high serum and urinary levels of light chains and the diagnosis was performed by renal biopsy, examined using immunofluorescence and by electron microscopy that showed light chain paraproteins. Nephropathy of light-chain deposition disease occurs due to an over-production of light chains from immunoglobulins produced by B lymphocytes with a deposit in tubular and glomerular membranes.

Iron deficiency anemia and megaloblastic anemia in obese patients.

Science.gov (United States)

Arshad, Mahmoud; Jaberian, Sara; Pazouki, Abdolreza; Riazi, Sajedeh; Rangraz, Maryam Aghababa; Mokhber, Somayyeh

2017-03-01

The association between obesity and different types of anemia remained uncertain. The present study aimed to assess the relation between obesity parameters and the occurrence of iron deficiency anemia and also megaloblastic anemia among Iranian population. This cross-sectional study was performed on 1252 patients with morbid obesity that randomly selected from all patients referred to Clinic of obesity at Rasoul-e-Akram Hospital in 2014. The morbid obesity was defined according to the guideline as body mass index (BMI) equal to or higher than 40 kg/m2. Various laboratory parameters including serum levels of hemoglobin, iron, ferritin, folic acid, and vitamin B12 were assessed using the standard laboratory techniques. BMI was adversely associated with serum vitamin B12, but not associated with other hematologic parameters. The overall prevalence of iron deficiency anemia was 9.8%. The prevalence of iron deficiency anemia was independent to patients' age and also to body mass index. The prevalence of vitamin B12 deficiency was totally 20.9%. According to the multivariable logistic regression model, no association was revealed between BMI and the occurrence of iron deficiency anemia adjusting gender and age. A similar regression model showed that higher BMI could predict occurrence of vitamin B12 deficiency in morbid obese patients. Although iron deficiency is a common finding among obese patients, vitamin B12 deficiency is more frequent so about one-fifth of these patients suffer vitamin B12 deficiency. In fact, the exacerbation of obesity can result in exacerbation of vitamin B12 deficiency.

Cold agglutinin disease (CADwith autoimmune haemolytic anaemia: a case report of a coronary artery disease patient Doença por aglutininas a frio (DAC com anemia hemolítica auto-imune: relato de caso de um coronariopata

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Leandro A. Barbosa

2008-02-01

Full Text Available Cold agglutinin disease (CAD with autoimmune haemolytic anemia is characterized by the production of harmful cold autoantibodies associated with increased red cell destruction during exposure to cold. The treatment of CAD is very difficult and a great effort is required to obtain therapeutic success. Cyclophosphamide is a potent immunosuppressive agent which is widely used in all bone marrow transplantation conditioning regimens for patients with acquired severe aplastic anemia. In this report, we describe the case of a coronary artery disease patient with severe CAD, but without lymphoproliferative disease, in which general measures and immunosuppressive therapies were adopted, there by avoiding blood transfusions.A doença por aglutininas a frio (CAD cursando com anemia hemolítica auto-imune (AHAI é decorrente da produção de autoanticorpos que reagem muito bem a baixas temperaturas, dirigidos contra hemácias autólogas. A habilidade desses anticorpos em destruir as hemácias encontra-se diretamente relacionada à sua capacidade em fixar complemento durante a exposição do paciente a baixas temperaturas. A AHAI por anticorpos frios pode ser idiopática - ausência de doença de base - ou secundária, geralmente associada a desordens linfoproliferativas de células B ou determinados processos infecciosos. A hemólise é intravascular, através de aglutininas da classe IgM, com teste direto da antiglobulina humana positivo para complemento. O tratamento da CAD é difícil, exigindo um esforço contínuo, necessário para se obter sucesso terapêutico. A ciclofosfamida é um agente imunossupressor potente, amplamente utilizado em transplantes de medula óssea, particularmente nos portadores de anemia aplástica. Descrevemos o caso de um coronariopata portador de CAD severa, cuja exploração diagnóstica excluiu doença linfoproliferativa. Adotamos medidas gerais de suporte e terapia imunossupressora, coibindo o uso de hemotransfusões.

Subpopulações dos reticulócitos e fração de reticulócitos imaturos como indicadores de aumento da eritropoese em doentes com anemia por deficiência de ferro Reticulocyte subpopulations and immature reticulocyte fractions as indicators of increased erythropoiesi in patients with iron deficiency anaemia

Directory of Open Access Journals (Sweden)

Ana R. João

2008-01-01

Full Text Available O objetivo deste trabalho é o de estudar as subpopulações dos reticulócitos e a fração de reticulócitos imaturos (IFR enquanto indicadores de atividade eritropoética em pacientes com anemia por deficiência de ferro e determinar o seu grau de correlação com os marcadores tradicionais de deficiência de ferro. Estudamos um total de 96 indivíduos, com idades compreendidas entre os 20 e os 86 anos, divididos em dois grupos: indivíduos controle (n=30 e indivíduos com anemia por deficiência de ferro (n=66. A todos eles foi efetuado hemograma completo, incluindo contagem de reticulócitos e os seus índices de maturação, ferro, transferrina, ferritina e capacidade total de fixação do ferro. Os indivíduos com anemia por deficiência de ferro mostraram um aumento da proporção de IFR quando comparados com o grupo controle (15.02 ± 9.70% vs 6.43 ± 3.98%, pThe aim of this work is to investigate reticulocyte subpopulations and immature reticulocyte fractions as indicators of bone marrow erythropoietic activity in patients with iron-deficiency anemia and their correlations with traditional hematological and biochemical markers of iron deficiency. A total of 96 individuals, aged 20 to 86 years old, were included in this study. These individuals were divided into two groups: healthy controls (n=30 and iron-deficiency anemia (n=66. Complete blood counts including reticulocytes and their subpopulations, iron, ferritin and transferrin and total binding capacity were determined in all individuals. Patients with iron-deficiency anemia had an increased proportion of immature reticulocyte fractions when compared with controls (15.02 ± 9.70% vs. 6.43 ± 3.98%, p<0.01, respectively. Comparing patients with healthy controls, the investigation of the subpopulations revealed higher medium-fluorescent reticulocyte (12.69 ± 6.69% vs. 5.88 ± 3.59%, respectively p<0.01 and high-fluorescent reticulocyte (1.45 [0.38-3.10] vs. 0.40 [0.00-0.90], p<0

Iron, Anemia, and Iron Deficiency Anemia among Young Children in the United States

OpenAIRE

Gupta, Priya M.; Perrine, Cria G.; Mei, Zuguo; Scanlon, Kelley S.

2016-01-01

Iron deficiency and anemia are associated with impaired neurocognitive development and immune function in young children. Total body iron, calculated from serum ferritin and soluble transferrin receptor concentrations, and hemoglobin allow for monitoring of the iron and anemia status of children in the United States. The purpose of this analysis is to describe the prevalence of iron deficiency (ID), anemia, and iron deficiency anemia (IDA) among children 1–5 years using data from the 2007–201...

Anemia muy precoz del prematuro con peso ≤ 1 500 g:: prevalencia y factores asociados Very early anemia in premature weighing ≤ 1 500 g:: prevalence and associated factors

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Yusleivy Milagros López Negrín

2010-06-01

Full Text Available INTRODUCCIÓN. En el Hospital Ginecoobstétrico Docente «Ramón González Coro» no se ha estudiado la prevalencia de la anemia muy precoz de la prematuridad y los factores asociados a su aparición. Se decidió realizar esta investigación para dar respuesta a esta interrogante y proporcionar bases a las autoridades administrativas para el trazado de estrategias preventivas más eficaces, que reduzcan esta complicación y sus consecuencias. MÉTODOS. Se realizó un estudio prospectivo, de corte transversal, donde se incluyeron todos los recién nacidos (RN ≤ de 1 500 g nacidos antes de las 37 semanas y atendidos en el servicio de neonatología del hospital durante el año 2008. El universo de estudio estuvo constituido por 25 neonatos. Se determinó en cada uno la presencia o no de anemia muy precoz. Se determinó la prevalencia de esta enfermedad y los factores maternos, perinatales y posnatales asociados. RESULTADOS. Presentó anemia muy precoz el 52 % de los neonatos (13/25. La hemoglobina materna baja no se asoció a la anemia muy precoz (RP 0,62; IC 95 % 0,21-1,80. Ninguna variable perinatal se asoció a la anemia muy precoz, aunque se encontró que la prevalencia de esta enfermedad disminuye al aumentar la edad gestacional al nacer (tendencia lineal: X² 4,33; gl 1; p 0,037. Los RN con alguna morbilidad grave tuvieron 2,44 veces más probabilidad de presentar anemia muy precoz (RP 2,44; IC 95 % 1,01-5,87. La prevalencia de la anemia muy precoz se incrementó al aumentar los mililitros por kilogramo de peso de sangre extraída (tendencia lineal: X² 7,6195; gl 1; p 0,0058. Los RN con extracciones entre 5 y 10 mL/kg y > 10 mL/kg tuvieron 5,3 y 4,5 veces más probabilidad de presentar anemia (RP 5,33; IC 95 % 1,4739-19,2988 y RP4,5 ; IC 95 % 1,1254-17,9930, respectivamente. CONCLUSIONES. Un poco más de la mitad de los casos presentaron anemia muy precoz y los factores independientes asociados a su aparición fueron la presencia de

Iron-Deficiency Anemia

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Full Text Available ... your doctor may recommend you eat heart-healthy foods or control other conditions that can cause iron-deficiency anemia. Blood tests to screen for iron-deficiency anemia To screen ...

Iron-Deficiency Anemia

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Full Text Available ... from developing iron-deficiency anemia. Foods that are good sources of iron include dried beans, dried fruits, eggs, lean red meat, ... signs of iron-deficiency anemia include: Brittle nails ...

Iron-Deficiency Anemia

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Full Text Available ... for iron-deficiency anemia. Lifestyle habits Certain lifestyle habits may increase your risk for iron-deficiency anemia, including: Vegetarian or vegan eating patterns. Not eating enough iron-rich foods, such ...

Iron-Deficiency Anemia

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Full Text Available ... Hemophilia Pernicious Anemia Restless Legs Syndrome Von Willebrand Disease Other Resources NHLBI resources Your Guide to Anemia [PDF, 1.54MB] Cardiovascular Health Study Recipient Epidemiology Donor Studies (REDS) program ...

Sickle cell anemia

Science.gov (United States)

Anemia - sickle cell; Hemoglobin SS disease (Hb SS); Sickle cell disease ... Sickle cell anemia is caused by an abnormal type of hemoglobin called hemoglobin S. Hemoglobin is a protein inside red blood cells ...

Aquisição de conceito de número por pessoas com deficiência intelectual Adquisición de concepto de número por personas com deficiencia intelectual Number concept acquisition by people with intelectual disabilities

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Giovana Escobal

2010-09-01

Full Text Available Esse estudo investigou o processo de aquisição do conceito de número por pessoas com deficiência intelectual. Dele participaram duas pessoas, respectivamente de idade 16 e 20 anos de idade, alunos de uma escola especial. Para avaliar o repertório inicial dos participantes utilizou-se um programa computacional baseado na noção de rede de relações entre estímulos e entre estímulos e respostas. Depois foram ensinadas as relações tidas como necessárias para a avaliação de repertório, seguidas de testes para avaliar as relações emergentes. Os resultados mostraram a eficácia do currículo informatizado sugerido e dos procedimentos de ensino utilizados, tendo sido constatada a aquisição do conceito de número em reduzido período de tempo. Uma rede de relações matemáticas foi formada a partir do ensino direto de apenas duas relações. O ensino informatizado otimizou o processo de ensino-aprendizagem, aumentou a confiabilidade dos dados e controlou as contingências, de forma a ensinar conforme o planejado.Este estudio evaluó la adquisición del concepto de número por personas com deficiencia intelectual. Dos personas participaron, edad entre 16 y 20 años, estudiantes de una escuela de educación especial. Un programa de ordenador evaluó el repertorio de los participantes basados en una tela de relaciones entre estímulos y entre estímulos y respuestas, identificando las relaciones presentes y ausentes, y para la enseñanza y la prueba de las relaciones condicionales. La fase próxima consistió en la enseñanza de las relaciones reveladas necesarias, seguidas por la prueba inmediata para evaluar relaciones inesperadas. Los resultados demonstraron la eficacia del plan de estudios computarizado sugerido y la eficacia de los procedimientos de enseñanza usados, debido la adquisición del concepto de número en un período de tiempo reducido. Una tela de relaciones matemáticas se formó con la enseñanza directa de solamente

Vitamin Deficiency Anemia

Science.gov (United States)

... are unique to specific vitamin deficiencies. Folate-deficiency anemia risk factors include: Undergoing hemodialysis for kidney failure. ... the metabolism of folate. Vitamin B-12 deficiency anemia risk factors include: Lack of intrinsic factor. Most ...

Drug-induced immune hemolytic anemia

Science.gov (United States)

Immune hemolytic anemia secondary to drugs; Anemia - immune hemolytic - secondary to drugs ... Drugs that can cause this type of hemolytic anemia include: Cephalosporins (a class of antibiotics), most common ...

Thiamine– Responsive Megaloblastic Anemia Syndrome

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F Motavaselian

2009-01-01

Full Text Available Thiamine Responsive megaloblastic anemia in DIDMOA (Wolfram syndrome has an autosomal- recessive mode of inheritance . Megaloblastic anemia and sideroblastic anemia is accompanied by diabetes insipidus (DI, diabetes mellitus (DM ,optic atrophy (OA and deafness (D. Neutropenia and thrombocytopenia are also present. We report a 7 month old girl with congenital macrocytic anemia; a rare clinical feature of Wolfram,s syndrome with increased plasma levels of blood glucose, both of which dramatically responded to administration of thiamine in large doses . The patient also had neurosensorial deafness, but no improvement was observed in the deafness. We presented the case because thiamine-responsive megaloblastic anemia is a rare clinical presentation of Wolfram syndrome and after institution of treatment with thiamine, the anemia and hyperglycemia returned to normal.

Influência da anemia ferropriva no eletroforetrograma de hemoglobina de leitões

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Cruz, Nathan da Rocha Neves [UNESP

2016-01-01

A hemoglobina é uma proteína globular composta por fração protéica (cadeias de globina), fração heme onde ocorre a ligação do íon bivalente de ferro, sendo que, as globinas combinadas ajudam a tipificar as hemoglobina em Hb Adulta (Hb A), Fetal (Hb F) e Adulta 2 (Hb A2). Na deficiência de ferro, que pode culminar anemia por disfunção eritropoiética, prevalente em leitões e seres humanos, a hemoglobina pode ter alterações estruturais denominadas hemoglobinopatias. O estudo determinou a influên...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... may be diagnosed with iron-deficiency anemia if you have low iron or ferritin levels in your blood. More testing may be needed to rule out other types of anemia. Tests for gastrointestinal ...

Consumo de leite de vaca e anemia ferropriva na infância Cow's milk consumption and iron deficiency anemia in children

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Maria A. A. Oliveira

2005-10-01

Full Text Available OBJETIVO: Revisar aspectos do consumo de leite de vaca associados à anemia na infância. FONTES DOS DADOS: As informações foram coletadas a partir de artigos publicados nas 2 últimas décadas, pesquisados nas bases de dados Lilacs e MEDLINE, livros técnicos e publicações de organizações internacionais. SÍNTESE DOS DADOS: A anemia ferropriva é um grave problema de saúde pública nos países em desenvolvimento. Até os 6 meses de idade, o leite materno supre as necessidades de ferro das crianças nascidas a termo. A partir daí, torna-se necessária a ingestão de uma alimentação complementar rica em ferro. Considerando a importância da dieta na determinação da anemia e o alto consumo de leite de vaca na infância, discute-se neste artigo a relação desse alimento com a deficiência de ferro. A introdução precoce ou a substituição do leite materno por leite de vaca pode ocasionar problemas gastrintestinais e alérgicos. Além disso, esse alimento apresenta baixa biodisponibilidade e densidade de ferro, excesso de proteínas e minerais, especialmente cálcio, interferindo na absorção do ferro de outros alimentos, e associa-se às micro-hemorragias intestinais, principalmente nas crianças menores. CONCLUSÕES: A utilização do leite de vaca em detrimento de outros alimentos ricos em ferro biodisponível constitui um risco para o desenvolvimento da anemia. O estímulo ao aleitamento materno exclusivo até os 6 meses de vida e sua continuidade até pelo menos 24 meses, juntamente com uma dieta complementar rica em ferro são medidas de grande importância para a prevenção da anemia e de suas conseqüências na infância.OBJECTIVE: To thoroughly investigate the association between the consumption of cow's milk and anemia in childhood. SOURCES OF DATA: The information was gathered from papers catalogued in Lilacs and MEDLINE and published during the last two decades, and also from textbooks and publications by international

Anemia of Chronic Disease and Iron Deficiency Anemia in Inflammatory Bowel Diseases: Pathophysiology, Diagnosis, and Treatment.

Science.gov (United States)

Murawska, Natalia; Fabisiak, Adam; Fichna, Jakub

2016-05-01

Anemia coexists with inflammatory bowel disease (IBD) in up to two-thirds of patients, significantly impairing quality of life. The most common types of anemia in patients with IBD are iron deficiency anemia and anemia of chronic disease, which often overlap. In most cases, available laboratory tests allow successful diagnosis of iron deficiency, where difficulties appear, recently established indices such as soluble transferrin-ferritin ratio or percentage of hypochromic red cells are used. In this review, we discuss the management of the most common types of anemia in respect of the latest available data. Thus, we provide the mechanisms underlying pathophysiology of these entities; furthermore, we discuss the role of hepcidin in developing anemia in IBD. Next, we present the treatment options for each type of anemia and highlight the importance of individual choice of action. We also focus on newly developed intravenous iron preparations and novel, promising drug candidates targeting hepcidin. Concurrently, we talk about difficulties in differentiating between the true and functional iron deficiency, and discuss tools facilitating the process. Finally, we emphasize the importance of proper diagnosis and treatment of anemia in IBD. We conclude that management of anemia in patients with IBD is tricky, and appropriate screening of patients regarding anemia is substantial.

Anemia of Chronic Liver Diseases

International Nuclear Information System (INIS)

Shin, Hyun Chung; Lee, Jhung Sang; Koh, Chang Soon; Lee, Mun Ho

1971-01-01

The pathogenetic mechanisms of anemia in patients with chronic liver disease were observed. Seventeen patients with moderate to advanced hepatic diseases were studied by various methods. Only patients without previous blood loss were included : 14 had cirrhosis, 2 had active chronic hepatitis, and one had inferior vena cava obstruction with associated liver cirrhosis. The followings were the results: 1. The anemia based on red blood cell count, Hb., and Ht. was found in 76.5-78.6% of the patients. 2. Red cell indices indicated that normo-macrocytic and normochromic anemia was present is the majority of the patients. 3. No evidence of megaloblastic anemia was found on the basis of the morphological examinations. 4. Serum iron, TIBC, % saturation and iron content in the bone marrow indicated that iron deficiency anemia was present in about half of the patients. 5. In the view of the erythrocyte dynamics, primary increase in the red cell destruction was ascribed to the cause of the anemia. 6. Decrease in the red cell survival time was not correlated with MCV, % saturation and S.L. ratio. Also, hemoglobin level was not correlated with MCV, % saturation and T 50 Cr. Therefore, multiple causes may be involved in the pathogenesis of the anemia. 7. Anemia as determined by the red cell volume was found in only 60% of the patients. It may be possible that hemodilutional anemia is present.

Iron-Deficiency Anemia

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Full Text Available ... deficiency anemia can cause serious complications, including heart failure and development delays in children. Explore this Health ... to iron-deficiency anemia include: End-stage kidney failure, where there is blood loss during dialysis. People ...

Iron-Deficiency Anemia

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Full Text Available ... deficiency anemia can cause serious complications, including heart failure and development delays in children. Explore this Health ... lead to iron-deficiency anemia include: End-stage kidney failure, where there is blood loss during dialysis. ...

Iron-Deficiency Anemia

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Full Text Available ... iron-deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. Treating anemia in ... Visit Children and Clinical Studies to hear experts, parents, and children talk about their experiences with clinical ...

Iron-Deficiency Anemia

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Full Text Available ... contribute to differences in disease severity and how patients respond to treatment. The NHLBI Strategic Vision highlights ... Anemia in Chronic Kidney Disease (National Institute of Diabetes and Digestive and Kidney Diseases) Avoiding Anemia (National ...

Iron-Deficiency Anemia

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Full Text Available ... to improve health through research and scientific discovery. Improving health with current research Learn about the following ... deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. Treating anemia in premature ...

Iron-Deficiency Anemia

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Full Text Available ... with the Eunice Kennedy Shriver National Institute of Child Health and Human Development, we are investigating how ... Anemia in Chronic Kidney Disease (National Institute of Diabetes and Digestive and Kidney Diseases) Avoiding Anemia (National ...

Iron-Deficiency Anemia

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Full Text Available ... iron-deficiency anemia. These conditions include: Intestinal and digestive conditions, such as celiac disease; inflammatory bowel diseases, ... iron-deficiency anemia , such as bleeding in the digestive or urinary tract or heavy menstrual bleeding, your ...

Iron-Deficiency Anemia

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Full Text Available ... mg and women need 18 mg. After age 51, both men and women need 8 mg. Pregnant ... for iron-deficiency anemia. Learn about exciting research areas that NHLBI is exploring about iron-deficiency anemia. ...

Iron-Deficiency Anemia

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Full Text Available ... heart failure . Increased risk of infections Motor or cognitive development delays in children Pregnancy complications, such as ... for iron-deficiency anemia. Learn about exciting research areas that NHLBI is exploring about iron-deficiency anemia. ...

Iron-Deficiency Anemia

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Full Text Available ... heavy menstrual periods. Individuals with a gene for hemophilia, including symptomatic female carriers who have heavy menstrual ... Heart-Healthy Lifestyle Changes Heart Failure Hemolytic Anemia Hemophilia Pernicious Anemia Restless Legs Syndrome Von Willebrand Disease ...

Iron-Deficiency Anemia

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Full Text Available ... conditions that can cause iron-deficiency anemia. Blood tests to screen for iron-deficiency anemia To screen ... the size of your liver and spleen. Blood tests Based on results from blood tests to screen ...

Iron-Deficiency Anemia

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Full Text Available ... less than 12 g/dl for women is diagnostic of anemia. In iron-deficiency anemia, red blood ... both full-term and preterm infants. Look for Diagnosis will explain tests and procedures that your doctor ...

Iron-Deficiency Anemia

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Full Text Available ... iron-fortified foods that have iron added. Vegetarian diets can provide enough iron if you choose nonmeat ... Anemia in Chronic Kidney Disease (National Institute of Diabetes and Digestive and Kidney Diseases) Avoiding Anemia (National ...

Iron-Deficiency Anemia

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Full Text Available ... less than 12 g/dl for women is diagnostic of anemia. In iron-deficiency anemia, red blood ... physical exam, or order blood tests or other diagnostic tests. Physical exam Your doctor may ask about ...

Iron-Deficiency Anemia

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Full Text Available ... and pregnancy. Good sources of iron are meat, poultry, fish, and iron-fortified foods that have iron ... Anemia Restless Legs Syndrome Von Willebrand Disease Other Resources NHLBI resources Your Guide to Anemia [PDF, 1. ...

Iron-Deficiency Anemia

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Full Text Available ... learning how having iron-deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. ... iron-deficiency anemia in blood donors affects the quality of donated red blood cells, such as how ...

Side Effects: Anemia

Science.gov (United States)

Anemia is a side effect of cancer treatments, including chemotherapy and radiation therapy. It can make women and men feel fatigued, dizzy, and short of breath. Learn how to manage fatigue caused by anemia during cancer treatment.

Iron-Deficiency Anemia

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Full Text Available ... endoscopy or colonoscopy, to stop bleeding. Healthy lifestyle changes To help you meet your daily recommended iron ... iron-deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. Treating anemia in ...

Iron-Deficiency Anemia

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Full Text Available ... leaving cells where it is stored or from being absorbed in the duodenum, the first part of ... treatments for iron-deficiency anemia. Living With After being diagnosed with iron-deficiency anemia, it is important ...

Molecular study of the gene FANCA in patients with compatible clinical of Fanconi Anemia

OpenAIRE

Claudia Estela Gonçalves

2014-01-01

Resumo: A Anemia de Fanconi (AF) é uma alteração genética caracterizada por múltiplas anomalias congênitas, anormalidades hematológicas e predisposição a uma variedade de tumores. A incidência mundial da AF em todo o mundo é de aproximadamente três por milhão e a frequência de heterozigotos é estimada em um para 300 na Europa e Estados Unidos. É uma doença causada por mutações em genes relacionados ao sistema de reparo. Até o momento foram descritos 16 genes que podem estar multados. São eles...

Iron-Deficiency Anemia

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Full Text Available ... iron-deficiency anemia. Search the NIH Research Portfolio Online Reporting Tools (RePORT) to learn about research that ... iron-deficiency anemia in blood donors affects the quality of donated red blood cells, such as how ...

Cancer-related anemia

International Nuclear Information System (INIS)

Abdel-Rzaeq, Hikmat N.

2004-01-01

Anemia is the most common hematological abnormality in cancer patients is often under-recognized and undertreated. The pathogenesis of cancer anemia is complex and most of time multifactorial; involving factors related to the tumor itself or its therapy. While anemia can be present in a wide range of symptoms, involing almost every organ, it is beleived that it contributes much to cancer-related-fatigue, one of the most common symptoms in cancer patients. In addition there is increasing evidence to suggest that anemia is an independent factor adversely affecting tumor reponse and patient survival. While blood transfusion was the only option to treat cancer related anemia, the use of recombinant human erythropoietin (rHuEPO) is becomig the new standard of care, more so with the recent studies demonstrating the feasibility of a sigle weekly injection .Things are even getting better with the recent approval of a new form of rHuEPO; Darbepoetin an analogue with a 3-fold longer half-life. In addition to its effects in raising homoglobin, several well controlled studies demonstrated decrease in transfusion requirementsand better qualify of life assessed objectively using standard assesments scales. (author)

Iron deficiency or anemia of inflammation? : Differential diagnosis and mechanisms of anemia of inflammation.

Science.gov (United States)

Nairz, Manfred; Theurl, Igor; Wolf, Dominik; Weiss, Günter

2016-10-01

Iron deficiency and immune activation are the two most frequent causes of anemia, both of which are based on disturbances of iron homeostasis. Iron deficiency anemia results from a reduction of the body's iron content due to blood loss, inadequate dietary iron intake, its malabsorption, or increased iron demand. Immune activation drives a diversion of iron fluxes from the erythropoietic bone marrow, where hemoglobinization takes place, to storage sites, particularly the mononuclear phagocytes system in liver and spleen. This results in iron-limited erythropoiesis and anemia. This review summarizes current diagnostic and pathophysiological concepts of iron deficiency anemia and anemia of inflammation, as well as combined conditions, and provides a brief outlook on novel therapeutic options.

Iron-Deficiency Anemia

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Full Text Available ... other conditions that can cause iron-deficiency anemia. Blood tests to screen for iron-deficiency anemia To screen ... check the size of your liver and spleen. Blood tests Based on results from blood tests to screen ...

Sickle cell anemia.

OpenAIRE

ŘÍHOVÁ, Tereza

2013-01-01

This thesis is about the disease called sickle cell anemia, or drepanocytosis. In this thesis is described the history of the disease, pathophysiology, laboratory features, various clinical features, diferencial diagnosis, quality of life in sickle cell anemia and therapy.

Iron-Deficiency Anemia

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Full Text Available ... blocks the intestine from taking up iron. Other medical conditions Other medical conditions that may lead to iron-deficiency anemia ... daily amount of iron. If you have other medical conditions that cause iron-deficiency anemia , such as ...

Iron-Deficiency Anemia

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Full Text Available ... hemoglobin levels. This was associated with a greater risk of death even with mild anemia. Now, anemia in older adults is recognized as an important condition. NHLBI Small Business Program. Through the NHLBI Small Business Program , we ...

Iron-Deficiency Anemia

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Full Text Available ... loss and lead to iron-deficiency anemia. Common causes of blood loss that lead to iron-deficiency anemia include: Bleeding in your GI tract, from an ulcer, colon cancer, or regular use of medicines such as aspirin ...

Iron-Deficiency Anemia

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Full Text Available ... for iron-deficiency anemia. Lifestyle habits Certain lifestyle habits may increase your risk for iron-deficiency anemia, including: Vegetarian or vegan eating patterns. Not eating enough iron-rich foods, such as meat and fish, may result in ...

Iron-Deficiency Anemia

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Full Text Available ... even with mild anemia. Now, anemia in older adults is recognized as an important condition. NHLBI Small Business Program. Through the NHLBI Small Business Program , we fund research and development for domestic small businesses that have strong potential ...

Iron-Deficiency Anemia

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Full Text Available ... anemia. Return to Signs, Symptoms, and Complications to review signs and symptoms as well as complications from iron-deficiency ... NIH]) Heavy Menstrual Bleeding (Centers for Disease Control and ... Dietary Supplement Fact Sheet (NIH) Iron-Deficiency Anemia (National Library ...

Iron-Deficiency Anemia

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Full Text Available ... be at risk for iron-deficiency anemia. Lifestyle habits Certain lifestyle habits may increase your risk for iron-deficiency anemia, ... you are experiencing side effects such as a bad metallic taste, vomiting, diarrhea, constipation, or upset stomach. ...

Iron-Deficiency Anemia

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Full Text Available ... how we are using current research and advancing research to prevent iron-deficiency anemia. Participate in NHLBI Clinical Trials will explain our ongoing clinical studies that are investigating prevention strategies for iron-deficiency anemia. Signs, Symptoms, and Complications ...

Iron-Deficiency Anemia (For Parents)

Science.gov (United States)

... Videos for Educators Search English Español Iron-Deficiency Anemia KidsHealth / For Parents / Iron-Deficiency Anemia What's in ... common nutritional deficiency in children. About Iron-Deficiency Anemia Every red blood cell in the body contains ...

PREVENÇÃO E TRATAMENTO DE ÚLCERAS POR PRESSÃO NO COTIDIANO DE ENFERMEIROS INTENSIVISTAS

Directory of Open Access Journals (Sweden)

Jaiany Alencar Rolim

2013-01-01

Full Text Available Estudio exploratorio con objetivo de identificar las acciones de prevención y tratamiento de ulceras por presión, planeadas y/o ejecutadas por enfermeros en la Unidad de Cuidados Intensivos, la importancia atribuida a las intervenciones y las dificultades encontradas en la ejecución de estas. Se llevó a cabo en una Unidad de Cuidados Intensivos de Hospital Universitario, con la participación de nueve enfermeras. Los datos obtenidos a través de entrevistas se analizaron de acuerdo a técnica del Discurso del Sujeto Colectivo, y destacó el cambio de posición entre las medidas de prevención y atención curativa como el tratamiento principal de la úlcera por presión. Las dificultades señaladas por las enfermeras fueron las deficiencias en recursos humanos, en número, la formación y falta de adhesión de los miembros del equipo; y en los recursos materiales para promover la comodidad y seguridad del paciente.

Anemia of Chronic Liver Diseases

Energy Technology Data Exchange (ETDEWEB)

Shin, Hyun Chung; Lee, Jhung Sang; Koh, Chang Soon; Lee, Mun Ho [Seoul National University College of Medicine, Seoul (Korea, Republic of)

1971-09-15

The pathogenetic mechanisms of anemia in patients with chronic liver disease were observed. Seventeen patients with moderate to advanced hepatic diseases were studied by various methods. Only patients without previous blood loss were included : 14 had cirrhosis, 2 had active chronic hepatitis, and one had inferior vena cava obstruction with associated liver cirrhosis. The followings were the results: 1. The anemia based on red blood cell count, Hb., and Ht. was found in 76.5-78.6% of the patients. 2. Red cell indices indicated that normo-macrocytic and normochromic anemia was present is the majority of the patients. 3. No evidence of megaloblastic anemia was found on the basis of the morphological examinations. 4. Serum iron, TIBC, % saturation and iron content in the bone marrow indicated that iron deficiency anemia was present in about half of the patients. 5. In the view of the erythrocyte dynamics, primary increase in the red cell destruction was ascribed to the cause of the anemia. 6. Decrease in the red cell survival time was not correlated with MCV, % saturation and S.L. ratio. Also, hemoglobin level was not correlated with MCV, % saturation and T{sub 50} Cr. Therefore, multiple causes may be involved in the pathogenesis of the anemia. 7. Anemia as determined by the red cell volume was found in only 60% of the patients. It may be possible that hemodilutional anemia is present.

Anemia pós-cirurgia bariátrica: as causas nem sempre são relacionadas à cirurgia Anemia after bariatric surgery: the causes sometimes are not related to the surgery

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Giorgio Alfredo Pedroso Baretta

2008-06-01

Full Text Available RACIONAL: As anemias ferropriva, perniciosa e megaloblástica são comuns após procedimentos bariátricos como o bypass e as derivações biliopancreáticas. As principais causas devem-se ao desvio duodenal e do jejuno proximal do trânsito alimentar e, em menor grau, às úlceras anastomóticas. Entretanto a dieta pobre em nutrientes, a suplementação vitamínica inadequada, medicamentos, uso de álcool e neoplasias devem ser lembrados. RELATO DOS CASOS: Os autores relatam dois casos de pacientes pós-procedimentos bariátricos com anemia severa sem controle clínico e cuja investigação identificou melanoma metastático em um caso e neoplasia colônica no segundo, ambos tratados cirurgicamente com bons resultados. CONCLUSÃO: Anemias são comuns após procedimentos bariátricos, porém causas atípicas como neoplasias devem ser suspeitadas nos pacientes mais idosos e principalmente naqueles refratários ao controle clínico.BACKGROUND: Iron deficiency anemia, pernicious and megaloblastic are common after gastric bypass and biliopancreatic diversion. The main causes are due to duodenal exclusion and anastomotic ulcers. However, low protein diet, vitaminic supplementation, medicines, alcohol and tumors must be remembered. CASES REPORT: The authors relate two cases of severe anemia after bariatric procedures that were diagnosed as metastatic melanoma in small bowel and a colorectal cancer treated surgically with good results. CONCLUSION: Anemias are common after bariatric surgery, however unusual causes like tumors must be suspected in the elderly and in those patients that clinical treatment didn't have good results.

Estado nutricional del hierro en gestantes adolescentes, Medellín, Colombia / Nutritional status of iron in pregnant adolescents, Medellín, Colombia

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Beatriz E. Parra S

2014-04-01

Full Text Available Objetivo: analizar el estado nutricional del hierro en gestantes adolescentes de tercer trimestre. Metodología: estudio analítico de corte transversal con 276 adolescentes entre 10 y 19 años, en tercer trimestre de gestación de la Empresa Social del Estado (ese Metrosalud (Medellín, 2011-2012, con datos de hemoglobina, volumen corpuscular medio, concentración de hemoglobina corpuscular media e ingesta de suplemento de hierro. La ferritina sérica se analizó en 178 gestantes, controlada por proteína C-reactiva. Se utilizaron medidas de tendencia central, dispersión, porcentajes y pruebas de Chi2 , anova, Kruskal-Wallis y U de Mann-Whitney. Resultados: la prevalencia de anemia fue 17,1% en el tercer trimestre de gestación y por deficiencia de hierro, 51%. La mediana de ferritina sérica fue 13,3 µg/L (RQ: 7,7 µg/L-17,9 µg/L; sólo el 5,6% (n = 9 presentó valores adecuados de ferritina. Las madres que tomaron suplemento de hierro diariamente presentaron mejores concentraciones de hemoglobina y ferritina, frente a aquellas que no lo hicieron, Hb 12,1g/dL vs. 11,7 g/dL (p = 0,019 y ferritina sérica 14,6 µg/L vs. 7,0 µg/L (p = 0,000. Discusión: hubo altas prevalencias de anemia y ferropenia en las gestantes, asociadas con la no adherencia al suplemento de hierro Objetivo: analizar el estado nutricional del hierro en gestantes adolescentes de tercer trimestre. Metodología: estudio analítico de corte transversal con 276 adolescentes entre 10 y 19 años, en tercer trimestre de gestación de la Empresa Social del Estado (ese Metrosalud (Medellín, 2011-2012, con datos de hemoglobina, volumen corpuscular medio, concentración de hemoglobina corpuscular media e ingesta de suplemento de hierro. La ferritina sérica se analizó en 178 gestantes, controlada por proteína C-reactiva. Se utilizaron medidas de tendencia central, dispersión, porcentajes y pruebas de Chi2 , anova, Kruskal-Wallis y U de Mann-Whitney. Resultados: la prevalencia

Iron-Deficiency Anemia

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Full Text Available ... if you are diagnosed with iron-deficiency anemia. Risk Factors You may have an increased risk for iron-deficiency anemia because of your age, ... or sex. Age You may be at increased risk for iron deficiency at certain ages: Infants between ...

Iron-Deficiency Anemia

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Full Text Available ... Are you curious about how inflammation from chronic diseases can cause iron-deficiency anemia? Read more When there is ... DBDR) is a leader in research on the causes, prevention, and treatment of blood diseases, including iron-deficiency anemia. Search the NIH Research ...

Iron-Deficiency Anemia

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Full Text Available ... iron-deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. Treating anemia in premature or very small newborns . In collaboration with the Eunice Kennedy Shriver National Institute of Child Health and Human Development, we are investigating how ...

Iron-Deficiency Anemia

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Full Text Available ... iron supplements work best to treat iron-deficiency anemia in children who do not consume the daily recommended amount ... and Clinical Studies to hear experts, parents, and children talk about their experiences with clinical ... Anemia Arrhythmia Blood Donation Blood Tests Blood ...

Iron-Deficiency Anemia

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Full Text Available ... stores are developed during the third trimester of pregnancy. Children between ages 1 and 2, especially if they drink a lot ... Resources NHLBI resources Your Guide to Anemia [PDF, ... (National Institute of Diabetes and Digestive and Kidney Diseases) Avoiding Anemia (National ...

Severe Anemia in Malawian Children

NARCIS (Netherlands)

Calis, J.C.J.; Kamija, S.P.; Faragher, E.B.; Brabin, B.J.; Bates, I.; Cuevas, L.E.; Haan, de R.J.; Phiri, A.I.; Malange, P.; Khoka, M.; Hulshof, P.J.M.; Lieshout, L.; Beld, M.G.H.M.; Teo, Y.Y.; Rockett, K.A.; Richardson, A.; Kwiatkowski, D.P.; Molyneux, M.E.; Hensbroek, van M.B.

2008-01-01

Background Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied. Methods We conducted a case¿control study of 381 preschool children with severe anemia (hemoglobin concentration,

A anemia falciforme como problema de Saúde Pública no Brasil

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Roberto B. de Paiva e Silva

1993-02-01

Full Text Available Apesar de a anemia falciforme ser a doença hereditária de maior prevalência no Brasil, a literatura nacional carece de investigações a respeito dos seus aspectos de Saúde Pública. Investigou-se a realidade vivida por 80 pacientes adultos (49 mulheres e 31 homens com diagnóstico de anemia falciforme, seguidos regularmente em centro hematológico. O diagnóstico tardio da doença foi um dos principais aspectos detectados na casuística examinada. Observou-se que a problemática maior do paciente adulto com a anemia falciforme esta centrada nos aspectos econômicos, sobretudo na falta de oportunidades profissionais, apesar de os mesmos poderem participar do mercado de trabalho, desde que estejam recebendo tratamento médico adequado e exerçam funções compatíveis com as suas limitações e potencialidades. A orientação psicoterapêutica teve uma grande aceitação pelos pacientes, sem diferença significativa entre os sexos. Concluiu-se haver necessidade da implantação de programas comunitários de diagnóstico precoce e de orientação médica, social e psicológica dos doentes com a anemia falciforme no Brasil, bem como de aconselhamento genético não diretivo dos casais de heterozigotos com o traço falciforme.

Fatores de risco de anemia em lactentes matriculados em creches públicas ou filantrópicas de São Paulo Risk factors for anemia in infants enrolled in public or philanthropic day-care centers in São Paulo city, Brazil

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Tulio Konstantyner

2007-08-01

Full Text Available OBJETIVO: Identificar e quantificar os fatores de risco de anemia em lactentes matriculados em creches públicas ou filantrópicas no município de São Paulo e discutir o impacto das ações da creche no controle desta carência nutricional específica. MÉTODO: Estudo seccional compreendendo 212 lactentes de duas creches públicas e três filantrópicas. Foram realizadas entrevistas com as mães, coleta de sangue por punção digital e antropometria. Considerou-se como anemia, hemoglobina inferior a 11g/dL. Foi ajustado um modelo de regressão logística para fatores de risco entre grupos de lactentes com e sem anemia. RESULTADOS: A prevalência de anemia foi de 51,9%. O modelo logístico final foi composto por 4 variáveis: presença de 1 ou mais irmãos menores que 5 anos (Odds Ratio=2,57; p=0,005; estar freqüentando creche de administração exclusivamente pública (Odds Ratio=2,12; p=0,020; uso de aleitamento materno exclusivo inferior a 2 meses (Odds Ratio=1,88; p=0,044, e idade inferior a 15 meses (Odds Ratio=2,32; p=0,006. CONCLUSÃO:Concluiu-se que a alta prevalência de anemia evidencia a ineficiência das creches estudadas para controlar e prevenir esta carência nutricional; portanto, cabe ao planejador de saúde considerar os riscos de anemia identificados e quantificados quando da elaboração de programas de controle e prevenção.OBJECTIVE: To identify and quantify the risk factors for anemia in infants enrolled in public or philanthropic day care centers in São Paulo city and discuss the impact of the actions of day care centers in controlling this specific nutritional deficiency. METHODS: Cross-sectional study comprising 212 infants of two public and three philanthropic day care centers. Interviews with the mothers, collection of blood by digital puncture and anthropometry were performed. Anemia was characterized by hemoglobin levels below 11g/dL. A logistic regression model for risk factors between groups of infants with

Anemia in the general population

DEFF Research Database (Denmark)

Martinsson, Andreas; Andersson, Charlotte; Andell, Pontus

2014-01-01

predictor of mortality, with the highest mortality observed for macrocytic anemia, which was less prevalent than microcytic and normocytic anemia. Dietary intake of iron and vitamin B12 were significantly lower and use of antithrombotic medications was significantly higher in subjects with anemia. The World...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... how having iron-deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. Treating anemia in premature or very small newborns . In collaboration with the Eunice Kennedy Shriver National Institute of Child Health and Human Development, we are investigating how ...

Iron-Deficiency Anemia

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Full Text Available ... anemia, including: Vegetarian or vegan eating patterns. Not eating enough iron-rich foods, such as meat and fish, may result in ... deficiency anemia, your doctor may recommend heart-healthy eating and choosing iron-rich foods, especially during certain stages of life when more ...

Iron-Deficiency Anemia

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Full Text Available ... iron-deficiency anemia early in life affects later behavior, thinking, and mood during adolescence. Treating anemia in premature or very small newborns . In collaboration with the Eunice Kennedy Shriver National Institute of Child Health and Human Development, we are investigating how best to treat ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... over 65 years of age had low hemoglobin levels. This was associated with a greater risk of death even with mild anemia. Now, anemia in older adults is recognized as an important condition. NHLBI Small Business Program. Through the NHLBI Small Business Program , we ...

Prevalência e caracterização da anemia em idosos do Programa de Saúde da Família Prevalence and characteristics of anemia in an elderly population attending a Health Family Program

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Diana L. Barbosa

2006-12-01

Full Text Available A anemia é considerada um problema de saúde pública em escala mundial e é o distúrbio hematológico de maior prevalência que acomete a população idosa. O objetivo deste trabalho foi estimar a prevalência e características da anemia em idosos do Programa de Saúde da Família de Camaragibe, PE. O delineamento foi transversal, com amostra aleatória sistemática de 284 idosos > 60 anos, de ambos os sexos, realizado em novembro/dezembro-2003. A anemia foi avaliada pela hemoglobina (Hb, concentração de hemoglobina corpuscular média (CHCM, volume corpuscular médio (VCM e amplitude de distribuição eritrocitária (RDW. A prevalência de anemia foi, em média, de 11,0%. A morfologia eritrocitária não mostrou associação com as concentrações de Hb. A grande maioria dos idosos apresentou anemia normocrômica, normocítica, sem anisocitose, sugestivo de anemia por doença crônica. A ínfima prevalência de microcitose e macrocitose com anisocitoseminimiza a gênese da deficiência de ferro, bem como da deficiência de vitamina B12 e ácido fólico na etiologia da anemia em idosos. Concluímos que o uso de indicadores que reflitam o grau de anisocitose eritrocitária associados àqueles que avaliam o estado nutricional do ferro é extremamente recomendado para o diagnóstico das anemias em idosos.Anemia is a serious public health problem worldwide that mainly affects children and women of childbearing age. However, data about anemia in elderly individuals are still scarce in developing countries. This study aimed at assessing the prevalence and characteristics of anemia among an elderly population attending the Health Family Program in Camaragibe, northeast Brazil. Following a systematic sampling procedure, a cross-sectional study was carried out in November and December 2003 involving 284 subjects of both genders with ages grater than or equal to 60 years old. Anemia was estimated by the measurement of hemoglobin, mean cell hemoglobin

A prescrição semanal de sulfato ferroso pode ser altamente efetiva para reduzir níveis endêmicos de anemia na infância Long-term preventive mass prescription of weekly doses of iron sulfate may be highly effective to reduce endemic child anemia

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Carlos Augusto Monteiro

2002-04-01

Full Text Available A anemia por deficiência de ferro em crianças é um dos maiores problemas nutricionais enfrentados pelos países em desenvolvimento. Estudos controlados indicam que doses intermitentes de sais de ferro podem ter eficácia semelhante à obtida com o esquema tradicional diário. O objetivo desse estudo é avaliar, em uma população onde a anemia na infância é endêmica, a efetividade da prescrição preventiva de doses semanais de sulfato ferroso a todas as crianças entre seis e 59 meses de idade por um período de seis meses. Crianças dos grupos controle e intervenção foram selecionadas a partir de uma amostra aleatória da população de crianças da cidade de São Paulo. Os pais das crianças do grupo intervenção receberam orientação nutricional e frascos de solução de sulfato ferroso com a instrução de ofertá-la aos filhos uma vez por semana até a próxima visita da equipe de pesquisa, que ocorreria em aproximadamente seis meses. Os pais das crianças do grupo controle receberam somente orientação nutricional. O efeito da intervenção foi avaliado por mudanças na concentração da hemoglobina e na prevalência de anemia. As comparações entre os dois grupos foram baseadas na "intenção-de-tratar" e todas as estimativas foram ajustadas para concentração inicial de hemoglobina, idade inicial, duração do seguimento e renda familiar. O ganho médio de hemoglobina devido à intervenção foi de 4,0 g/l e a queda na prevalência de anemia foi de mais de 50%. A intervenção foi particularmente eficiente em prevenir o declínio da concentração de hemoglobina durante os dois primeiros anos de vida. Esse estudo demonstra que, em condições similares àquelas que poderiam facilmente ser reproduzidas por programas regulares de saúde pública, a prescrição universal de doses semanais de sulfato ferroso reduz significativamente o risco de anemia na infância.Iron-deficiency anemia in children remains one of the most

Anemia: An approach to evaluation, 2014

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Philip Kuriakose

2015-01-01

Full Text Available Anemia is very commonly encountered in general clinical practice among all age groups. The more commonly used way to classify anemia has been to categorize it as being microcytic (mean corpuscular volume [MCV] 100 fL, which in turn allows for a more practical way to attempt to come up with a cause for any decrease in hemoglobin. Microcytic anemias are usually due to iron deficiency (in turn, a result of a number of different etiologies ranging from decreased intake, malabsorption, or blood loss, hemoglobinopathies (thalassemic syndromes, and some cases of severe anemia resulting from chronic disease. Normocytic anemia is often a result of anemia of chronic disease, hemolysis, or secondary to bone marrow failure. Macrocytic anemias are frequently caused by deficiencies of folic acid and/or Vitamin B12, exposure to toxic agents like drugs that interfere with DNA metabolism and alcohol, as also bone marrow failure states, such as from myelodysplastic syndrome. A comprehensive history, physical examination, and directed laboratory evaluation will help to identify a specific cause for anemia.

Severe anemia in Malawian children

NARCIS (Netherlands)

Calis, Job C. J.; Phiri, Kamija S.; Faragher, E. Brian; Brabin, Bernard J.; Bates, Imelda; Cuevas, Luis E.; de Haan, Rob J.; Phiri, Ajib I.; Malange, Pelani; Khoka, Mirriam; Hulshof, Paul J. M.; van Lieshout, Lisette; Beld, Marcel G. H. M.; teo, Yik Y.; Rockett, Kirk A.; Richardson, Anna; Kwiatkowski, Dominic P.; Molyneux, Malcolm E.; Boele van Hensbroek, Michael

2008-01-01

Background Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied. Methods We conducted a case-control study of 381 preschool children with severe anemia (hemoglobin concentration, <5.0 g per deciliter) and

Severe anemia in Malawian children

NARCIS (Netherlands)

Calis, Job Cj; Phiri, Kamija S.; Faragher, E. Brian; Brabin, Bernard J.; Bates, Imelda; Cuevas, Luis E.; de Haan, Rob J.; Phiri, Ajib I.; Malange, Pelani; Khoka, Mirriam; Hulshof, Paul Jm; van Lieshout, Lisette; Beld, Marcel Ghm; teo, Yik Y.; Rockett, Kirk A.; Richardson, Anna; Kwiatkowski, Dominic P.; Molyneux, Malcolm E.; van Hensbroek, Michaël Boele

2016-01-01

Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied. We conducted a case-control study of 381 preschool children with severe anemia (hemoglobin concentration, <5.0 g per deciliter) and 757 preschool

Anemia ferropriva e estado nutricional de crianças de creches de Guaxupé Anemia and nutritional status of children in day-care centers in Guaxupé

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Carlos César Camillo

2008-04-01

Full Text Available OBJETIVO: Avaliar o estado nutricional e a prevalência de anemia ferropriva de crianças que freqüentam creches no município de Guaxupé, MG. MÉTODOS: Foram incluídas no estudo crianças de ambos os sexos, de 6 a 72 meses de idade, matriculadas em creches do município de Guaxupé. O estado nutricional foi aferido por meio do escore Z das relações estatura para idade e peso para a estatura. Para o diagnóstico de anemia utilizou-se a dosagem de hemoglobina, ferro sérico, capacidade total de ligação de ferro e o índice de saturação de transferrina. RESULTADOS: Escore Z OBJECTIVE: To evaluate the nutritional status and the prevalence of iron deficiency anemia in children attending public day care centers in the city of Guaxupé (MG, Brazil. METHODS: Children of both genders, from 6 to 72 months, registered in public day-care centers in the city of Guaxupé, were studied. Nutritional evaluation was conducted using the Z-score for height-to-age and weight-to-height relationships. Hemoglobin dosage, serum iron, total iron binding capacity and the transferrin saturation index were used for diagnosis of anemia. RESULTS: Z score < - 2 was observed in 3.3% of the children for the height-to-age relationship and of 0.4% for the weight-to-height relationship. Prevalence of total iron deficiency anemia was of 16.1%. In the age span from 6 to 36 months it was of 44.6%. The entire sample showed 45% with low serum iron, 37.9% with high total iron binding capacity and 43.1% with a low transferrin saturation index. CONCLUSION: Malnutrition was not considered to be a problem due to its low prevalence; however, an important prevalence of iron deficiency was observed. Iron deficiency anemia is more prevalent in children between 6 and 36 months confirming that this age span is more vulnerable. No association between iron deficiency anemia and the Z score of the studied anthropometry relationships was found.

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... also are hoping to determine which iron supplements work best to treat iron-deficiency anemia in children who do not consume the daily recommended amount of iron. Read less Participate in NHLBI Clinical Trials We lead or sponsor many studies related to iron-deficiency anemia. See if you ...

Iron-Deficiency Anemia

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Full Text Available ... Precision Medicine Activities Obesity, Nutrition, and Physical Activity Population and Epidemiology Studies Women’s Health All Science A- ... to help your body absorb iron. Avoid drinking black tea, which reduces iron ... was associated with a greater risk of death even with mild anemia. Now, anemia in older ...

Intoxicação experimental por Indigofera suffruticosa em caprinos e ovinos

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Anna P.M. de Figueiredo

2012-02-01

Full Text Available Indigofera suffruticosa é uma planta invasora, ção. Em um caprino e um ovino foram realizados os testes que causa anemia hemolítica com hemoglobinúria em bo-de fragilidade osmótica, determinação de hemoglobina e vinos e, experimentalmente, anemia sem hemoglobinúria metemoglobina e pesquisa de corpúsculos de Heinz. Foi em cobaios. O objetivo deste trabalho foi determinar a comprovado que em caprinos e ovinos, I. suffruticosa cautoxicidade de I. suffruticosa para caprinos e ovinos. Par-sa anemia hemolítica sem hemoglobinúria com formação tes aéreas da planta foram administradas a seis caprinos de corpúsculos de Heinz. Os animais recuperaram-se da e quatro ovinos em doses diárias de 10, 20 e 40g por kg anemia, total ou parcialmente, mesmo com a continuidade de peso vivo, durante períodos de 2 a 24 dias. Foram ava-da administração da planta. Oito a 12 horas após a coleliados os parâmetros hematológicos (hematócrito, níveis ta observa-se pigmento azulado na urina. Sugere-se que o de hemoglobina e contagem de hemácias e foi coletada pigmento seja anilina ou algum metabolito dessa substânurina para urinálise e observação de variações na coloracia e que a anilina seja o princípio ativo responsável pela hemólise causada por I. suffruticosa.

Mortalidad por defectos del tubo neural en México, 1980-1997

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Ramírez-Espitia José A

2003-01-01

Full Text Available OBJETIVO: Describir la mortalidad en México por defectos del tubo neural, durante el periodo 1980-1997. MATERIAL Y MÉTODOS: Las tasas anuales de mortalidad estatales y nacionales, por defectos del tubo neural, se calcularon por 10 000 nacidos vivos. La tendencia temporal fue evaluada por el porcentaje de cambio anual obtenido mediante un modelo de regresión de Poisson. Se calculó la razón de mortalidad, tomando la media nacional como referencia. Las tasas y las razones se representaron gráficamente en mapas. RESULTADOS: Durante el periodo la tasa bruta de mortalidad por defectos del tubo neural fue de 5.8 por 10 000 nacidos vivos. La anencefalia fue el tipo de defecto más frecuente (37.7%, seguida de la espina bífida sin hidrocefalia (31.6%. La tendencia nacional de la mortalidad por defectos del tubo neural fue ascendente entre 1980 y 1990 (porcentaje de cambio anual 7.5 IC 95% 6.5, 8.6 y descendente entre 1990-1997 (porcentaje de cambio anual -2.3 IC 95% -3.6, -0.9. CONCLUSIONES: Las altas tasas de mortalidad por defectos del tubo neural fueron debidas principalmente a la elevada frecuencia de las anencefalias. El incremento observado parece no ser sólo atribuible a cuestiones puramente diagnósticas o de mejora en los registros. La influencia de factores asociados a estos defectos, como determinados polimorfismos genéticos, la deficiencia de ácido fólico, la obesidad materna, la exposición laboral a plaguicidas y la pobreza deberán evaluarse mediante estudios específicos.

Bases genéticas de la discapacidad intelectual y los trastornos del espectro autista: aplicación de las nuevas tecnologías al análisis de variantes del número de copias (CNVs)

OpenAIRE

Quintela García, Inés

2017-01-01

La discapacidad intelectual (DI) es un trastorno del neurodesarrollo complejo y fenotípicamente heterogéneo caracterizado por deficiencias significativas en el funcionamiento intelectual y en las habilidades adaptativas de inicio en el período del desarrollo. El trastorno del espectro autista (TEA) es un trastorno del neurodesarrollo caracterizado por deficiencias en las habilidades para la comunicación, en la interacción social y en el desarrollo del lenguaje y por la presencia de intereses ...

Hemoglobin measured by Hemocue and a reference method in venous and capillary blood: a validation study Hemoglobina medida por Hemocue y por un método de referencia en sangre venosa y capilar: estudio de validación

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Lynnette Neufeld

2002-06-01

Full Text Available Objective. To assess the comparability of hemoglobin concentration (Hb in venous and capillary blood measured by Hemocue and an automated spectrophotometer (Celldyn and to document the influence of type of blood (capillary or venous and analysis method on anemia prevalence estimates. Material and Methods. Between February and May 2000, capillary and venous samples were collected from 72 adults and children at Hospital del Niño Morelense (Morelos State Children's Hospital in Cuernavaca, Morelos, Mexico, and assessed for Hb using the Hemocue and Celldyn methods. Estimated Hb levels were compared using the concordance correlation coefficient and Student's t test for paired data. The sensitivity and specificity for anemia diagnosis were estimated and compared between type of blood and method of assessment. Results. Capillary blood had higher Hb (+0.5g/dl than venous blood in adults and children, as did samples assessed by Celldyn compared to Hemocue (+0.3g/dl. Specificity to detect anemia was adequate (>0.90 but sensitivity was low for capillary blood assessed by Hemocue (Objetivo. Evaluar la comparabilidad de la concentración de hemoglobina (Hb en sangre venosa y capilar medida por Hemocue y por espectrofotómetro automatizado (Celldyn, así como documentar la influencia del tipo de sangre (capilar o venosa y del método de análisis sobre la prevalencia de anemia. Material y métodos. De febrero a mayo de 2000, se recolectaron muestras de sangre capilar y venosa en 72 adultos y niños en el Hospital del Niño Morelense, Cuernavaca, Morelos, México. Se determinaron los niveles de Hb con los métodos Hemocue y Celldyn. Las cifras de Hb estimadas se compararon con el coeficiente de concordancia y la prueba pareada de t de Student. También se comparó la sensibilidad y especificidad para el diagnóstico de anemia, utilizando sangre de los dos tipos y métodos de análisis. Resultados. La Hb fue mayor en sangre capilar comparada con sangre venosa

Severe anemia in Malawian children.

Science.gov (United States)

Calis, Job Cj; Phiri, Kamija S; Faragher, E Brian; Brabin, Bernard J; Bates, Imelda; Cuevas, Luis E; de Haan, Rob J; Phiri, Ajib I; Malange, Pelani; Khoka, Mirriam; Hulshof, Paul Jm; van Lieshout, Lisette; Beld, Marcel Ghm; Teo, Yik Y; Rockett, Kirk A; Richardson, Anna; Kwiatkowski, Dominic P; Molyneux, Malcolm E; van Hensbroek, Michaël Boele

2016-09-01

Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied. We conducted a case-control study of 381 preschool children with severe anemia (hemoglobin concentration, <5.0 g per deciliter) and 757 preschool children without severe anemia in urban and rural settings in Malawi. Causal factors previously associated with severe anemia were studied. The data were examined by multivariate analysis and structural equation modeling. Bacteremia (adjusted odds ratio, 5.3; 95% confidence interval [CI], 2.6 to 10.9), malaria (adjusted odds ratio, 2.3; 95% CI, 1.6 to 3.3), hookworm (adjusted odds ratio, 4.8; 95% CI, 2.0 to 11.8), human immunodeficiency virus infection (adjusted odds ratio, 2.0; 95% CI, 1.0 to 3.8), the G6PD -202/-376 genetic disorder (adjusted odds ratio, 2.4; 95% CI, 1.3 to 4.4), vitamin A deficiency (adjusted odds ratio, 2.8; 95% CI, 1.3 to 5.8), and vitamin B 12 deficiency (adjusted odds ratio, 2.2; 95% CI, 1.4 to 3.6) were associated with severe anemia. Folate deficiency, sickle cell disease, and laboratory signs of an abnormal inflammatory response were uncommon. Iron deficiency was not prevalent in case patients (adjusted odds ratio, 0.37; 95% CI, 0.22 to 0.60) and was negatively associated with bacteremia. Malaria was associated with severe anemia in the urban site (with seasonal transmission) but not in the rural site (where malaria was holoendemic). Seventy-six percent of hookworm infections were found in children under 2 years of age. There are multiple causes of severe anemia in Malawian preschool children, but folate and iron deficiencies are not prominent among them. Even in the presence of malaria parasites, additional or alternative causes of severe anemia should be considered.

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... grams per deciliter (g/dl) for men and less than 12 g/dl for women is diagnostic of anemia. In iron-deficiency anemia, ... blood levels of iron will be low, or less than 10 micromoles per liter (mmol/L) for both men and women. Normal levels are 10 to 30 mmol/L. ...

Anemia in the Newborn

Science.gov (United States)

... Overview of Horseshoe Kidney Additional Content Medical News Anemia in the Newborn By Andrew W. Walter, MS ... for the Professional Version Blood Problems in Newborns Anemia in the Newborn Hemolytic Disease of the Newborn ...

Riscos isolados e agregados de anemia em crianças frequentadoras de berçários de creches Isolated and combined risks for anemia in children attending the nurseries of daycare centers

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Tulio Konstantyner

2009-06-01

Full Text Available OBJETIVO: Identificar e quantificar os fatores de risco isolados e agregados de anemia, proporcionando visão ampliada quanto à probabilidade da sua ocorrência. MÉTODOS: Estudo transversal com 482 crianças, entre 4 e 29 meses de idade, frequentadoras de berçários de creches públicas e filantrópicas do município de São Paulo (SP, que participaram de dois inquéritos (2004 e 2007. Foram realizadas entrevistas com as mães, coleta de sangue por punção digital e antropometria. Considerou-se anemia, hemoglobina inferior a 11 g/dL. Foi ajustado modelo de regressão logística não-condicional para fatores de risco de anemia, considerando-se estatisticamente significantes associações com p OBJECTIVE: To identify and quantify isolated and combined risk factors for anemia, providing a comprehensive view of the likelihood of its occurrence. METHODS: Cross-sectional study with 482 children aged 4 to 29 months attending the nurseries of philanthropic and public daycare centers in the city of São Paulo, Brazil, who participated in two surveys (2004 and 2007. Mothers were interviewed, blood was collected using digital puncture, and anthropometry was performed. Anemia was characterized by hemoglobin levels below 11 g/dL. Unconditional logistic regression was adjusted for anemia risk factors. A value of p < 0.05 indicated statistically significant associations. Post-test odds and likelihood ratios were calculated to define post-test probabilities. Epi-InfoTM 2000 and Stata 10.0 software packages were used for statistical analysis. RESULTS: Prevalence of anemia was 43.6% (95%CI 39.1-48.1. The final logistic model included five categorical variables: mother's age less than 28 years (OR = 1.50; p = 0.041, per capita income below half a minimum wage (OR = 1.56; p = 0.029, exclusive breastfeeding less than 2 months (OR = 1.71; p = 0.009, decrease in weight/age z score from birth to survey (OR = 1.47; p = 0.050, and age less than 17 months (OR = 2

Genetics Home Reference: Diamond-Blackfan anemia

Science.gov (United States)

... Home Health Conditions Diamond-Blackfan anemia Diamond-Blackfan anemia Printable PDF Open All Close All Enable Javascript ... view the expand/collapse boxes. Description Diamond-Blackfan anemia is a disorder of the bone marrow . The ...

Valores del hematocrito y prevalencia de anemia en escolares jujeños

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I. F. Bejeran

2003-08-01

Full Text Available El hematocrito (Hto, como indicador de anemia en individuos y poblaciones, experimenta variaciones en función de factores mesológicos y genéticos. La anemia constituye una enfermedad endémica cuya prevalencia en Argentina, en distintos grupos de edad y de riesgo y particularmente en escolares, es insuficientemente conocida. El objetivo de este trabajo fue conocer la variación del Hto en escolares de la ciudad de San Salvador de Jujuy localizada a 1200 m.s.n.m., evaluar la prevalencia de anemia y relacionar estas variaciones con las características socioeconómicas de la población. Los datos del Hto procedieron de 17.580 escolares de escuelas públicas y privadas. Para su análisis se agruparon por edad, sexo y nivel socio-económico. Se consideró como anémicos a los niños cuyo Hto se encontró por debajo de: a el valor mínimo aceptado para el nivel de 1200 m; b -2 desviaciones estándar. Para el análisis se empleó: ANOVA, c2 y coeficiente de correlación. Los valores promedio del Hto, independientemente de la edad, sexo y nivel socioeconómico, coinciden con los de la referencia ajustados para la altura. Se observaron: a diferencias intersexuales estadísticamente significativas, presentando los varones, valores superiores a los de las mujeres; b una tendencia al aumento del Hto con relación al incremento del nivel socioeconómico. La prevalencia de anemia, independientemente del criterio utilizado, fue baja en ambos sexos, grupos de edad y en todos los niveles socioeconómicos. Los valores del hematocrito: a son representativos de una población escolar situada a una altitud moderada; b pese a la tendencia a disminuir en el nivel socioeconómico bajo no superan, en la mayoría de los casos, el nivel crítico de anemia; c no indican presencia de desnutrición en la población escolar examinada.The hematocrit (Ht, as an indicator of anemia in individuals and populations, shows variations in relation to mesologic and genetic factors

Incidencia de factores de riesgo asociados a la anemia ferropénica en niños menores de cinco años

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Mercedes Silva Rojas

2014-12-01

Full Text Available Se estima que más de 2 mil millones de personas en el mundo presentan déficit de hierro, más de la mitad está anémica y que la población infantil es más susceptible, por tener escasos depósitos y un crecimiento acelerado. Con el objetivo de identificar la presencia de factores de riesgo asociados a la anemia en niños de seis meses a cinco años de edad, en un Consultorio Médico de Familia (CMF del municipio Güines, provincia Mayabeque, se realizó esta investigación. Se efectuó un estudio descriptivo, prospectivo, de corte transversal, del 1ro de abril al 30 de septiembre de 2013, con el universo de niños de este grupo de edad, pertenecientes al CMF No1 del Policlínico Docente “Luis Li Trigent” del referido municipio y provincia; y la muestra quedó conformada por 32 niños, a los que se les diagnosticó anemia. El 46,9 % de los niños de seis a 23 meses de edad presentaron anemia con ligero predominio en el sexo masculino (53,1 %. Los factores de riesgo asociados más frecuentes en la muestra de estudio fueron: la anemia materna, 75 %; la no profilaxis a los niños con sales de hierro, 71,9 %; la no lactancia materna exclusiva hasta los seis meses de edad (65,7 % y las infecciones, 81,2 %. La anemia ligera fue más frecuente, 90,6 %. Estos resultados permiten identificar la incidencia de factores de riesgo asociados a la anemia, paso previo para realizar acciones que los modifiquen

Deficiencia congénita de proteína C en un recién nacido con trombosis y necrosis de tejidos extensa

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Bárbara Acosta Batista

Full Text Available Uno de los trastornos hematológicos más graves del período neonatal es la deficiencia congénita de proteína C, de presentación muy rara, y causa de enfermedad tromboembólica severa y púrpura fulminante en recién nacidos. Se puede sintetizar como una entidad clínico-patológica, de aparición aguda, con trombosis de la vasculatura de la dermis, lo cual conduce a necrosis hemorrágica y progresiva de la piel, asociada a coagulación intravascular diseminada y hemorragia perivascular, que ocurre en el período neonatal. El paciente presentado exhibe los elementos clínico-patológicos que caracterizan la púrpura fulminante, cuyo origen se debe a una deficiencia hereditaria de proteína C, lo cual condujo a la aparición de complicaciones trombóticas severas.

Anemia of Inflammation and Chronic Disease

Science.gov (United States)

... AI/ACD. AI/ACD is easily confused with iron- deficiency anemia because in both forms of anemia levels of ... cell production. Low blood iron levels occur in iron-deficiency anemia because levels of the iron stored in the ...

Análisis económico del comportamiento de la dependencia por regiones

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Herranz Peinado, Patricia

2008-01-01

Full Text Available Se puede considerar al fenómeno de la dependencia como un tema de fervienteactualidad, aunque bien es cierto que la necesidad de cuidado de aquellas personas que nopueden hacer por sí mismas las actividades más comunes de la vida diaria no es nada nuevo. Enla primera parte de este trabajo analizamos los perfiles sociales, económicos y de salud de estecolectivo mediante el estudio de la Encuesta sobre Discapacidades, Deficiencias y Estados deSalud de 1999, tomando las variables que mejor describan dicho estado y, enfatizando en ladificultad de seleccionar las variables que distinguen a los dependientes del resto dediscapacitados, se estudia el comportamiento económico por regiones. En la segunda parte seanaliza el coste de la dependencia bajo criterios diferentes tras la aprobación de la Ley dePromoción de la Autonomía Personal y Atención a las personas en situación de dependencia y,por último, se presenta una valoración teórica de la “deuda implícita” que el Estado adquierecon la cobertura de dependencia

Predictors of anemia in women of reproductive age: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project.

Science.gov (United States)

Wirth, James P; Woodruff, Bradley A; Engle-Stone, Reina; Namaste, Sorrel Ml; Temple, Victor J; Petry, Nicolai; Macdonald, Barbara; Suchdev, Parminder S; Rohner, Fabian; Aaron, Grant J

2017-07-01

Background: Anemia in women of reproductive age (WRA) (age range: 15-49 y) remains a public health problem globally, and reducing anemia in women by 50% by 2025 is a goal of the World Health Assembly. Objective: We assessed the associations between anemia and multiple proximal risk factors (e.g., iron and vitamin A deficiencies, inflammation, malaria, and body mass index) and distal risk factors (e.g., education status, household sanitation and hygiene, and urban or rural residence) in nonpregnant WRA. Design: Cross-sectional, nationally representative data from 10 surveys ( n = 27,018) from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project were analyzed individually and pooled by the infection burden and risk in the country. We examined the severity of anemia and measured the bivariate associations between anemia and factors at the country level and by infection burden, which we classified with the use of the national prevalences of malaria, HIV, schistosomiasis, sanitation, and water-quality indicators. Pooled multivariate logistic regression models were constructed for each infection-burden category to identify independent determinants of anemia (hemoglobin concertation <120 g/L). Results: Anemia prevalence was ∼40% in countries with a high infection burden and 12% and 7% in countries with moderate and low infection burdens, respectively. Iron deficiency was consistently associated with anemia in multivariate models, but the proportion of anemic women who were iron deficient was considerably lower in the high-infection group (35%) than in the moderate- and low-infection groups (65% and 71%, respectively). In the multivariate analysis, inflammation, vitamin A insufficiency, socioeconomic status, and age were also significantly associated with anemia, but malaria and vitamin B-12 and folate deficiencies were not. Conclusions: The contribution of iron deficiency to anemia varies according to a country's infection

Predictors of anemia in women of reproductive age: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project

Science.gov (United States)

Woodruff, Bradley A; Petry, Nicolai; Macdonald, Barbara; Aaron, Grant J

2017-01-01

Background: Anemia in women of reproductive age (WRA) (age range: 15–49 y) remains a public health problem globally, and reducing anemia in women by 50% by 2025 is a goal of the World Health Assembly. Objective: We assessed the associations between anemia and multiple proximal risk factors (e.g., iron and vitamin A deficiencies, inflammation, malaria, and body mass index) and distal risk factors (e.g., education status, household sanitation and hygiene, and urban or rural residence) in nonpregnant WRA. Design: Cross-sectional, nationally representative data from 10 surveys (n = 27,018) from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project were analyzed individually and pooled by the infection burden and risk in the country. We examined the severity of anemia and measured the bivariate associations between anemia and factors at the country level and by infection burden, which we classified with the use of the national prevalences of malaria, HIV, schistosomiasis, sanitation, and water-quality indicators. Pooled multivariate logistic regression models were constructed for each infection-burden category to identify independent determinants of anemia (hemoglobin concertation Anemia prevalence was ∼40% in countries with a high infection burden and 12% and 7% in countries with moderate and low infection burdens, respectively. Iron deficiency was consistently associated with anemia in multivariate models, but the proportion of anemic women who were iron deficient was considerably lower in the high-infection group (35%) than in the moderate- and low-infection groups (65% and 71%, respectively). In the multivariate analysis, inflammation, vitamin A insufficiency, socioeconomic status, and age were also significantly associated with anemia, but malaria and vitamin B-12 and folate deficiencies were not. Conclusions: The contribution of iron deficiency to anemia varies according to a country’s infection burden. Anemia

Anemia aplásica adquirida e anemia de Fanconi - Diretrizes Brasileiras em Transplante de Células-Tronco Hematopoéticas Acquired aplastic anemia and Fanconi anemia - Brazilian Guidelines in Hematopoietic Stem Cell Transplantation

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Larissa A. Medeiros

2010-05-01

Full Text Available As diretrizes apresentadas neste trabalho foram elaboradas e aprovadas na I Reunião de Diretrizes Brasileiras em Transplante de Células-Tronco Hematopoéticas (TCTH realizada no Rio de Janeiro, entre os dias 19 e 21 de julho de 2009. O evento foi promovido pela SBTMO (Sociedade Brasileira de Transplante de Medula Óssea. Neste artigo, tratamos da anemia aplásica severa (AAS, considerada uma urgência hematológica, que, identificada e manejada de forma precoce, apresenta grande possibilidade de recuperação da hematopoese seja através de transplante de medula óssea ou terapia imunossupressora. Objetiva-se nortear o manejo terapêutico no contexto do transplante e indicar formas de condicionamento, de acordo com as características clínicas dos pacientes, como o número de transfusões, com intuito de minimizar a rejeição primária e secundária, garantindo a melhora da sobrevida global e livre de doença (observadas pela literatura e já validadas por resultados na população brasileira. No que concerne à anemia de Fanconi, o transplante é a única modalidade curativa para o componente aplásico de medula óssea; embora não modificando as outras características da síndrome também demanda perícia e agilidade na busca de um doador com resultados expressivos de sobrevida.The guidelines presented in this article have been prepared and approved in the I Meeting of Brazilian Guidelines in Hematopoietic Stem Cell Transplantation (HSCT - Rio de Janeiro, July 19-21, 2009. The event was sponsored by SBTMO (Brazilian Society of Bone Marrow Transplantation. In this paper, we treat the severe aplastic anemia (SAA, considered a hematological emergency, that when identified and medically treated early, shows a great chance of recovery of the hematopoiesis, either through bone marrow transplantation or immunosuppressive therapy. Its objective is to guide the management of the transplantation, and indicate methods of conditioning, according to

APLASTIC ANEMIA

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Ni Made Dharma Laksmi

2013-07-01

Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Aplastic Anemia describes a disorder of the clinical syndrome is marked by a deficiency of red blood cells, neutrophils, monocytes and platelets in the absence of other forms of bone marrow damage. Aplastic anemia is classified as a rare disease in developed countries the incidence of 3-6 cases / 1 million inhabitants / year. The exact cause of someone suffering from aplastic anemia also can not be established with certainty, but there are several sources of potential risk factors. Prognosis or course of the disease varies widely aplastic anemia, but without treatment generally gives a poor prognosis /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

Fanconi Anemia — Case Report of Rare Aplastic Anemia at Child

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Deaconu Alina

2014-06-01

Full Text Available Introduction: Fanconi anemia is an autosomal recessive disease characterized by congenital abnormalities, defective haematopoiesis, and a high risk of developing acute myeloid leukaemia, myelodysplastic syndrome and cancers. FA was first described in 1927 by the Swiss pediatrician Guido Fanconi. The diagnosis is based on morphological abnormalities, hematologic abnormalities (pancytopenia, macrocytic anemia and progressive bone marrow failure and genetic tests (cariograma.

Genetic diagnosis for congenital hemolytic anemia.

Science.gov (United States)

Ohga, Shouichi

2016-01-01

Congenital hemolytic anemia is a group of monogenic diseases presenting with anemia due to increased destruction of circulating erythrocytes. The etiology of inherited anemia accounts for germline mutations of the responsible genes coding for the structural components of erythrocytes and extra-erythrocytes. The erythrocyte abnormalities are classified into three major disorders of red cell membrane defects, hemoglobinopathies, and red cell enzymopathies. The extra-erythrocyte abnormalities, typified by consumption coagulopathy and intravascular hemolysis, include Upshaw-Schulman syndrome and atypical hemolytic uremic syndrome. The clinical manifestations of congenital hemolytic anemia are anemia, jaundice, cholelithiasis and splenomegaly, while the onset mode and severity are both variable. Genetic overlapping of red cell membrane protein disorders, and distinct frequency and mutation spectra differing among races make it difficult to understand this disease entity. On the other hand, genetic modifiers for the phenotype of β-globin diseases provide useful information for selecting the optimal treatment and for long-term management. Recently, next generation sequencing techniques have enabled us to determine the novel causative genes in patients with undiagnosed hemolytic anemias. We herein review the concept and strategy for genetic diagnosis of inherited hemolytic anemias.

Diseño de un modelo de cobranzas de créditos de consumo otorgados por el sistema financiero y viabilización del aplicativo informátivo (SAC) para disminuir el índice de morosidad en cuentas por cobrar en cartera de consumo en la ciudad de Guayaquil

OpenAIRE

Bonifaz Yambay, Jacqueline; Verdezoto Dias, Ronald

2013-01-01

En la actualidad existen muchos factores que se presentan en las instituciones financieras que otorgan créditos de consumo específicamente con tarjetas de crédito, que causan un sinnúmero de problemas tanto a nivel de instituciones bancarias como en cada una de las aéreas y sus procesos en una determinada organización. Este tipo de inconvenientes se produce por deficiencias y debilidades operativas, así como en la falta de información además de no contar con indicadores que les permita med...

Genetics Home Reference: iron-refractory iron deficiency anemia

Science.gov (United States)

... refractory iron deficiency anemia Iron-refractory iron deficiency anemia Printable PDF Open All Close All Enable Javascript ... expand/collapse boxes. Description Iron-refractory iron deficiency anemia is one of many types of anemia , which ...

Deficiencia de glucosa-6-fosfato deshidrogenasa en un paciente con síndrome de Down

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Francisco R. Cammarata Scalisi; Harry Sánchez; Graciela Cammarata Scalisi; Nayra Cabral Alfonso; Osmoire Moreno; Miguel Alonzo Bastardo Ramos; Gustavo Gil

2012-01-01

El síndrome de Down, es una alteración genética que ocurre cuando un individuo exhibe todo o una parte específica adicional del cromosoma 21 y es la entidad más frecuentemente asociada a retardo mental. La deficiencia de glucosa-6-fosfato deshidrogenasa, es el defecto enzimático más común en humanos y presenta patrón de herencia ligado al cromosoma X recesivo. Se debe a la mutación del gen G6PD, el cual causa diversos fenotipos bioquímicos y clínicos. Reportamos un caso de lactante menor masc...

Guía didáctica estratégica dirigida al docente que labora en la educación infantil con niños de cinco años que presentan deficiencia auditiva

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Dra. C. Marigina del Carmen Guzmán

2018-02-01

Full Text Available El propósito de este artículo está dirigido a difundir la importancia de la inclusión de niños con discapacidades diferentes, a través de la implementación de una guía didáctica estratégica dentro de los planteles educativos, para brindar herramientas con actividades y recursos didácticos, a los docentes, promoviendo de esta manera que la inclusión de niños con deficiencia auditiva sea eficaz. Metodológicamente el estudio estuvo enmarcado en una investigación de campo, de nivel descriptivo de corte transversal. La población estuvo representada por 12 docentes que laboran en la institución objeto de estudio. La recolección de la información se realizó a través de la técnica de la encuesta y el instrumento fue un cuestionario conformado por 20 ítems. Los resultados arrojaron debilidades en los docentes en cuanto al manejo de estrategias para la inclusión de los niños que presentan discapacidades

Anemia e insuficiência cardíaca na comunidade: comparação com um ambulatório especializado Anemia e insuficiencia cardiaca en la comunidad: comparación con un consultorio especializado Anemia and heart failure in a community-based cohort: comparison with a specialized outpatient clinic

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Eduarda Barcellos dos Santos

2010-01-01

Full Text Available FUNDAMENTO: A anemia é comum em pacientes com insuficiência cardíaca (IC. Sua prevalência em pacientes com IC na comunidade é desconhecida em nosso meio. OBJETIVO: Avaliar a prevalência e características de pacientes com anemia em uma população não selecionada com IC na comunidade, comparando-a a uma população com IC atendida em um ambulatório especializado. MÉTODOS: Estudo transversal, prospectivo, observacional, realizado de janeiro de 2006 a março de 2007. Os pacientes com IC preenchiam os critérios de Boston, com pontuação >8. Anemia foi definida pelos critérios da Organização Mundial de Saúde, como valores de hemoglobina FUNDAMENTO: La anemia es común en pacientes con insuficiencia cardiaca (IC. Su prevalencia en pacientes con IC en la comunidad es desconocida en nuestro medio. OBJETIVO: Evaluar la prevalencia y características de pacientes con anemia en una población con IC no seleccionada en la comunidad, comparándola a una población con IC atendida en un consultorio especializado. MÉTODOS: Estudio transversal, prospectivo, observacional, realizado de enero de 2006 a marzo de 2007. Los pacientes con IC cumplían los criterios de Boston, con puntuación >8. La anemia fue definida por los criterios de la Organización Mundial de la Salud, como valores de hemoglobina BACKGROUND: Anemia is common in patients with heart failure (HF. Its prevalence in patients with HF from a community-based cohort is unknown in our country. OBJECTIVE: evaluate the prevalence and characteristics of patients with anemia in a non-selected population with HF from a community-based cohort, comparing it with that of a HF population treated at a specialized outpatient clinic. METHODS: This was a transversal, prospective, observational study, carried out from January 2006 to March 2007. The patients with HF met the Boston criteria, with a score > 8. Anemia was defined through the criteria of the World Health Organization as hemoglobin levels

Anemia e desnutrição em escolares da rede pública do município de Osasco, São Paulo, Brasil Anemia and malnutrition in children at public schools in Osasco, São Paulo, Brazil

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Maria Lúcia R. Stefanini

1995-09-01

Full Text Available Com o objetivo de estimar a prevalência de anemia e conhecer o estado nutricional de escolares, foi realizado um estudo em uma amostra dos alunos ingressantes nas primeiras séries do primeiro grau das escolas públicas de Osasco, município integrante da Região Metropolitana de São Paulo. O diagnóstico de anemia foi feito através da dosagem da concentração de hemoglobina do sangue colhido por punção digital. O nível crítico utilizado para caracterizar a presença de anemia foi o estabelecido pela OMS. O estado nutricional foi avaliado utilizando os indicadores peso/idade e altura/idade expressos em escores Z e a população de referência do NCHS. A prevalência, de anemia encontrada foi de 51%n. Houve diferença nos níveis de prevalência quanto à localização geográfica das escolas, sendo maior (56,9% na Região Periférica do que na Região Central (41,7%. A presença de anemia também foi mais elevada em crianças cujos pais eram analfabetos. O risco de anemia foi superior entre as crianças que ingressaram no primeiro grau com idade superior a 8 anos. Não foi constatada presença significante de desnutrição aguda. Os resultados deste estudo destacam a anemia entre escolares como importante problema de Saúde Pública e ressaltam a urgência da implantação de programas de controle da anemia na população de escolares.The authors studied a sample of students entering the first grade in the Osasco public school system in order to determine both the prevalence of anemia and nutritional status. Osasco is part of the Greater São Paulo Metropolitan Area. Diagnosis of anemia was made through the hemoglobin concentration of blood from digital puncture. World Health Organization (WHO levels were used to define anemia. Nutritional Status assessment. was made through weight/age and height/age indices, using Z score distribution and the National Center for Health Statistics (NCHS reference levels. Prevalence of anemia was 51

Manejo de la anemia en el paciente crítico

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María Fernanda Domínguez Freire

2018-01-01

Full Text Available La etiología de la anemia del paciente crítico se establece como multifactorial. Las pérdidas de sangre pueden causarse por cirugía, hemorragias, traumatismos, extracciones sanguíneas repetidas, entre otros factores que incluyen mecanismos inmunológicos. En ciertos casos, la aparición de la anemia del paciente crítico resulta anterior al ingreso en la unidad de cuidados intensivos y en otros se establece como un síntoma o comorbilidad de la patología médica o quirúrgica que ha provocado el ingreso, resultando uno de los principales factores de morbimortalidad en estos pacientes. Es, entonces, imprescindible dominar su etiopatogenia con el objetivo de su prevención, la realización de un diagnóstico correcto y la ejecución de un tratamiento apropiado con el fin de impedir o reducir sus efectos deletéreos. Este artículo se orienta a revisar el manejo y las metas del tratamiento antianémico del paciente crítico.

CORRECCIÓN DE LA DEFICIENCIA CRÓNICA DE ZINC EN AGUACATE "HASS"

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S. Salazar-García

2008-01-01

Full Text Available En los huertos de aguacate "Hass" de los municipios de Tepic y Xalisco, Nayarit, son frecuentes los niveles foliares debajo de lo normal de zinc (Zn y la presencia de síntomas visuales de deficiencia de Zn en hojas, brotes y frutos. Esta investigación se desarrolló del 2001 al 2005 en dos huertos comerciales de aguacate ''Hass'' cultivados sin riego en el municipio de Tepic con el objetivo de evaluar el efecto de las aplicaciones de sulfato de zinc (ZnSO4, al follaje o al suelo, sobre los niveles foliares de Zn, así como sobre la producción, tamaño y forma del fruto. El suelo de los huertos era de textura ligera, pH 5.8 y bajo contenido de Zn (1.4 a 3.13 mg.kg- 1. Los tratamientos al follaje fueron aplicados en 8 L agua/árbol y consistieron en: a una aspersión con 4,056 g ZnSO4.L-1 agua (1.46 g Zn, y b dos aspersiones con 2.28 g ZnSO4.L-1 agua (0.73 g Zn; ambos tratamientos proporcionaron 11.68 g Zn.árbol-1. Los tratamientos al suelo consistieron en: a una aplicación (1.5 kg, y b dos aplicaciones (0.75 kg c/u anuales de ZnSO4 (35.5 % Zn al suelo. El tratamiento control no recibió Zn. Las aspersiones foliares con ZnSO4 no corrigieron la deficiencia foliar de Zn, ni tuvieron efecto sobre la producción y tamaño del fruto. Dos aplicaciones al suelo con 0.75 kg ZnSO4.árbol-1.año resultaron en el mayor incremento del rendimiento, tamaño y forma (más alargada del fruto, reduciendo la cantidad de frutos pequeños y redondos. Este tratamiento también incrementó los niveles de Zn en las hojas y en la pulpa del fruto. Se encontró una pobre relación entre los niveles de ZnSO4 aplicados al suelo y el contenido foliar de Zn.

The challenge of microangiopathic hemolytic anemia

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Hassanain Hani Hassan

2017-01-01

Full Text Available Microangiopathic hemolytic anemia (MAHA is a Coomb's-negative hemolytic anemia characterized by red cell fragmentation (schistocytes. Thrombotic microangiopathy anemia, including thrombotic thrombocytopenia and hemolytic-uremic syndrome, malignant hypertension, preeclampsia are among the most common causes. We present a case of MAHA presenting with thrombocytopenia initially diagnosed as MAHA secondary to thrombotic thrombocytopenic purpura and received five sessions plasmapheresis without improvement but with worsening of anemia and thrombocytopenia. On further inquiry, glucose-6-phosphate dehydrogenase deficiency was identified, and the patient showed dramatic recovery after the trial of B12 and folate.

Metformin Therapy for Fanconis Anemia

Science.gov (United States)

2017-08-01

AWARD NUMBER: W81XWH-16-1-0300 TITLE: Metformin Therapy for Fanconis Anemia PRINCIPAL INVESTIGATOR: Markus Grompe CONTRACTING ORGANIZATION... Anemia 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-1-0300 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Markus Grompe 5d. PROJECT NUMBER 5e. TASK...298 (Rev. 8-98) Prescribed by ANSI Std. Z39.18 This award pertains to the treatment of the inherited bone marrow failure syndrome Fanconi’s Anemia

Parvovirose e anemia acentuada em paciente imunocompetente Parvovirus and severe anemia in an immunocompetent patient

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Juliana Annete Damasceno

2012-04-01

Full Text Available Paciente de 16 anos, sexo masculino, com vírus da imunodeficiência humana (HIV negativo e sem doença hematológica prévia, desenvolveu anemia acentuada devido à infecção por parvovírus B19. A doença apresentou evolução bifásica, com acalmia clínica e retorno dos sintomas após 15 dias. Ao exame físico, apresentava-se descorado e febril, sem adeno e organomegalias, com sinais de insuficiência cardíaca. O aspirado de medula óssea mostrava megaloblastos com nucléolos aberrantes e, na histologia, foram observadas células gigantes com nucleolação aberrante e presença do corpúsculo de inclusão nuclear típico da parvovirose. O exame de imuno-histoquímica mostrou positividade para anticorpo específico para parvovírus. A sorologia comprovou a infecção.A 16-year-old human immunodeficiency virus (HIV negative male patient without hematological disease developed acute anemia due to parvovirus B19 infection. The disease showed a biphasic evolution: clinical remission and return of symptoms after 15 days. Physical examination revealed paleness and fever, neither adeno nor organomegalies, and signs of heart failure. The bone marrow aspiration showed megaloblasts with aberrant nucleoli. As far as histology is concerned, giant cells with aberrant nucleoli and the presence of intranuclear inclusions typical of Parvoviruses were observed. Immunohistochemistry revealed positivity for specific Parvovirus antibody. Serology confirmed parvovirus B19 infection.

Anemia and survival in human immunodeficiency virus

DEFF Research Database (Denmark)

Lundgren, Jens Dilling; Mocroft, Amanda

2003-01-01

The prospective, multicenter cohort study EuroSIDA has previously reported on predictors and outcomes of anemia in patients infected with human immunodeficiency virus. In a Cox proportional-hazards model with serial measures of CD4+ cell count, plasma viral load, and degrees of anemia fitted...... as time-dependent variables, the relative hazard of death increased markedly for patients with anemia versus no anemia. A clinical scoring system was developed and validated for patients receiving highly active antiretroviral therapy using the most recent laboratory measures. Mild and severe anemia were...... independently (Panemia. The mechanisms underlying why hemoglobin is such a strong prognostic...

Genetics Home Reference: X-linked sideroblastic anemia

Science.gov (United States)

... Conditions X-linked sideroblastic anemia X-linked sideroblastic anemia Printable PDF Open All Close All Enable Javascript ... the expand/collapse boxes. Description X-linked sideroblastic anemia is an inherited disorder that prevents developing red ...

Special Issues for People with Aplastic Anemia

Science.gov (United States)

... Menu Donate Special Issues for People with Aplastic Anemia Because you have aplastic anemia , everyday events can ... bleeding, such as contact sports. Pregnancy and Aplastic Anemia Pregnancy is possible for women who have been ...

LAMA HAID DAN KEJADIAN ANEMIA PADA REMAJA PUTRI

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Febrianti Febrianti

2015-04-01

Full Text Available Latar belakang: Madrasah Aliyah Negeri (MAN 2 Bogor adalah sekolah dengan angka  prevalensi anemia tertinggi di kota Bogor. Dari pemeriksaan Puskesmas Bogor Timur pada tahun 2009, ada 65,8 persen  siswi sekolah tersebut yang menderita anemia. Tujuan:  Identifikasi faktor-faktor yang berhubungan dengan kejadian anemia. Metode: Penelitian kuantitatif dengan rancangan potong lintang. Variabel dependen adalah kejadian anemia. Variabel independen terdiri atas lama haid, frekuensi makan, kebiasaan makan buah-buahan, kebiasaan makan protein hewani, kebiasaan makan protein nabati, dan kebiasaan minum teh. Pengumpulan data dilakukan dua tahap yaitu pengisian kuesioner dan pengambilan sampel darah. Data dianalisis univariat dan bivariat. Hasil:  Ditemukan  hubungan  yang  bermakna  antara  lama  haid  dengan  kejadian  anemia remaja  putri  (p value=0.028. Variabel lain tidak memiliki hubungan yang bermakna dengan anemia.  Kesimpulan: Prevalensi anemia di MAN 2 Bogor berhubungan dengan lama haid dan tidak berhubungan dengan variabel lain.  Kata kunci: anemia remaja putri, faktor-faktor anemia, lama haid.

Avoiding Anemia: Boost Your Red Blood Cells

Science.gov (United States)

... Issues Subscribe January 2014 Print this issue Avoiding Anemia Boost Your Red Blood Cells En español Send ... Disease When Blood Cells Bend Wise Choices Preventing Anemia To prevent or treat iron-deficiency anemia: Eat ...

Avaliação da eficácia do uso intravenoso de sacarato de hidróxido de ferro III no tratamento de pacientes adultos com anemia ferropriva Evaluation of the efficacy of intravenous iron III-hydroxide saccharate for treating adult patients with iron deficiency anemia

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Rodolfo D. Cançado

2007-06-01

Full Text Available O objetivo desse estudo foi avaliar a eficácia do uso intravenoso de sacarato de hidróxido de ferro III no tratamento de pacientes adultos com anemia ferropriva. No período de janeiro de 2003 a dezembro de 2005, estudamos cinqüenta pacientes com anemia ferropriva que apresentaram intolerância e/ou resposta inadequada ao tratamento com ferro por via oral e/ou valor de hemoglobina inferior a 7,0 g/dL. Os principais exames laboratoriais realizados foram: hemograma completo, contagem de reticulócitos, ferro sérico, capacidade total de ligação de ferro e ferritina sérica. Os pacientes receberam uma dose semanal de 200 mg de sacarato de hidróxido de ferro III diluído em 250 mL de soro fisiológico a 0,9%, administrado por via intravenosa em trinta minutos. O tratamento foi realizado até a obtenção do valor de hemoglobina igual ou maior que 12,0 g/dL para mulheres e 13,0 g/dL para homens, ou até a administração da dose total de ferro parenteral recomendada para cada paciente. A idade mediana dos cinqüenta pacientes estudados foi de 45 anos, variando entre 28 e 76 anos; quarenta (80,0% eram do sexo feminino. A causa mais comum de anemia ferropriva no sexo feminino foi sangramento uterino anormal observado em 25/40 pacientes (62,5% e, no sexo masculino, gastrectomia parcial em 7/10 (70,0%. Vinte e quatro (48,0% pacientes foram incluídos nesse estudo por falta de resposta à terapia com ferro oral, 22 (44,0% por intolerância ao ferro oral e quatro (8,0% por hemoglobina The objective of this study was to evaluate the efficacy of intravenous iron III-hydroxide saccharate to treat adult patients with iron deficiency anemia. Between January 2003 and December 2005 we studied 50 patients with iron deficiency anemia who presented intolerance or inadequate response to oral iron therapy, or hemoglobin level < 7 g/dL. The main laboratory tests performed were: complete blood cell count, reticulocyte count, serum iron, total iron-binding capacity

Variáveis maternas e infantis associadas à ocorrência de anemia em crianças nos serviços de atenção básica em São Paulo Mother and child factors related to occurrence of anemia in children assisted at primary health care centers of São Paulo city, Brazil

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Patrícia Colombo Compri

2007-12-01

Full Text Available OBJETIVO: Analisar variáveis maternas e infantis associadas à ocorrência de anemia em crianças atendidas por serviços de atenção básica à saúde do município de São Paulo. MÉTODOS: Participaram do estudo 357 crianças, de quatro a 24 meses, de três serviços de atenção básica à saúde da região sul da cidade. As variáveis foram separadas em categorias relacionadas à mãe e à criança. A dosagem de hemoglobina foi realizada por punção digital, com ponto de corte de 11g/dL para o diagnóstico de anemia. O teste t de Student foi aplicado para comparar as médias de hemoglobina de dois grupos independentes; a ANOVA, para três ou mais grupos; e o teste de Mann-Whitney para comparar a velocidade de crescimento e o grupo etário. RESULTADOS: A prevalência de hemoglobina abaixo de 11g/dL foi de 60%. Entre as variáveis maternas, não se constatou associação com a ocorrência de anemia. Houve associação entre anemia, gênero da criança e velocidade de ganho de peso. Quanto à alimentação, não foi encontrada associação entre tempo de aleitamento materno e anemia, mas houve associação com a ingestão quantitativa e qualitativamente pobre em ferro. CONCLUSÕES: A alta prevalência de anemia relacionou-se ao gênero masculino, no qual a velocidade de crescimento em menores de seis meses e naqueles com 18 a 24 meses foi maior, além de se associar à baixa ingestão de ferro na dieta.OBJECTIVE: To analyze mother and child factors associated with the occurrence of anemia in children assisted at primary health care centers in São Paulo city, Brazil. METHODS: The study enrolled 357 children from four to 24 months assisted at three health care centers in the southern region of the city. Possible factors associated to anemia and related to mother and children characteristics were categorized. Hemoglobin was determined by digital puncture and the cut value for anemia diagnosis was 11g/dL. Student t test was used to compare the

Socio-economic and demographic determinants of childhood anemia

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Sankar Goswmai

2015-09-01

Full Text Available Objective: To evaluate socio-economic and demographic determinants of anemia among Indian children aged 6–59 months. Methods: Statistical analysis was performed on the cross-sectional weighted sample of 40,885 children from 2005 to 2006 National Family Health Survey by using multinomial logistic regression to assess the significance of some risk factors in different degrees of child anemia. Anemia was diagnosed by World Health Organization (WHO cut-off points on hemoglobin level. Pearson's chi-squared test was applied to justify the associations of anemia with different categories of the study population. Results: The prevalence of anemia was 69.5%; 26.2% mild, 40.4% moderate, and 2.9% severe anemia. Overall prevalence rate, along with mild and moderate cases, showed an increasing trend up to 2 years of age and then decreased. Rural children had a higher prevalence rate. Of 28 Indian states in the study, 10 states showed very high prevalence, the highest being Bihar (77.9%. Higher birth order, high index of poverty, low level of maternal education, mother's anemia, non-intake of iron supplements during pregnancy, and vegetarian mother increased the risks of all types of anemia among children (p < 0.05. Christian population was at lower risk; and Scheduled Caste, Scheduled Tribe, and Other Backward Class categories were at higher risk of anemia. Conclusion: The results suggest a need for proper planning and implementation of preventive measures to combat child anemia. Economically under-privileged groups, maternal nutrition and education, and birth control measures should be priorities in the programs. Resumo: Objetivo: Avaliar os fatores socioeconômicos e demográficos determinantes de anemia em crianças indianas com idade de 6 a 59 meses. Métodos: A análise estatística foi realizada na amostra transversal ponderada de 40885 crianças da Pesquisa Nacional de Saúde da Família de 2005–2006, Governo da Índia, utilizando a técnica de

Nutrición, suplementación, anemia y embarazo

OpenAIRE

Sánchez Salazar, Francisca Rosa; Trelles Aguabella, Edilia; Terán García, Reineria María; Pedroso Hernández, Patricia

2001-01-01

Se estudió, en el Hospital Ginecoobstétrico “Eusebio Hernández”, durante el período 1996 al 1997, a 180 gestantes, cuyas edades estaban entre 20 y 29 años, con anemia ferropénica. El objetivo fue conocer el efecto de la atención nutricional y la suplementación con hierro sobre los niveles de hierro sérico. Se crearon 2 grupos de 90 embarazadas cada uno: el grupo estudio, intolerantes a las sales ferroosas por vía bucal, recibió bioestimulin a razón de 9 mg de hierro hemínico diario y el contr...

Trastorno por déficit de atención e hiperactividad en escolares del municipio de Puerto Padre

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Liliana Almaguer Brito

2014-09-01

Full Text Available El diagnóstico del trastorno por déficit de atención e hiperactividad resulta complejo. Existen dificultades para la identificación de este trastorno en el municipio de Puerto Padre, provincia de Las Tunas, Cuba. Motivados por esa deficiencia, se decidió realizar un estudio de tipo descriptivo transversal. Para desarrollar el mismo se aplicaron cuestionarios a una muestra probabilística, estratificada por escuelas y sexos, de 314 alumnos de primer y segundo grado, con el fin de caracterizar el trastorno por déficit de atención e hiperactividad. Se aplicaron dos instrumentos, uno al total de la muestra, que tamiza el trastorno, y otro para confirmar el diagnóstico. Se obtiene una prevalencia del trastorno por déficit de atención e hiperactividad de un 5,4%, lo cual se encuentra dentro de los parámetros mundiales. Se clasifica el trastorno en subtipos: desatento (17,65%, hiperactivo impulsivo (29,41% y combinado (52,4%. La hiperactividad-impulsividad predominó en las hembras (40,0% contra 14,3% y la desatención en los varones (28,6% vs. 10,0%, el combinado resultó similar en ambos sexos

Aplastic anemia in Japanese radiological technicians

International Nuclear Information System (INIS)

Kitabatake, T.; Watanabe, T.; Saito, A.; Nakamura, M.; Shiohama Hospital, Mie

1976-01-01

Among the Japanese radiological technicians, four deaths from aplastic anemia have been reported after 1930. On the other hand, during the period from 1930 to 1960, the population of radiological technicians is estimated to be 74,400 man-years, in which 0.5 aplastic anemias are expected. However, actually three died from aplastic anemia. This difference is statistically significant at the 1% level. While, in the period from 1961 to 1973, the observed value is 1 against 0.7 expected. It is concluded that aplastic anemia had been induced frequently among the Japanese radiological technicians in the era when there was much exposure to occupational radiation. (orig.) [de

Estudio integrado sobre la anemia de Fanconi: aproximación a las bases moleculares del fallo medular y de la microftalmia

OpenAIRE

Prieto Remón, Inés

2013-01-01

RESUMEN: La anemia de Fanconi es una enfermedad genética rara. Presenta una gran heterogeneidad de síntomas clínicos, que van desde una aplasia medular precoz (pérdida del conjunto de células hematopoyéticasL pasando por una elevada tendencia a padecer cáncer hasta una gran variedad de anomalías congénitas. En esta tesis se ha realizado un estudio molecular sobre diferentes aspectos de la anemia de Fanconi en tres de los subtipos de la enfermedad (FA-A, FA-C y FA-D2) en un mode...

Ter anemia falciforme: nota prévia sobre seu significado para a criança expresso através da brincadeira Tener anemia falciforme: nota previa sobre el significado para el niño expresado a través del juego Having sickle-cell disease: short communication on the meaning for children as expressed through games what it means for them to have the disease

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Ana Augusta Maciel de Souza

2011-03-01

Full Text Available Nota prévia de uma pesquisa que tem como objetivo compreender o significado de ter anemia falciforme para crianças de 3 a 12 anos de idade, a partir de uma investigação qualitativa ancorada no Interacionismo Simbólico como referencial teórico, e na Teoria Fundamentada nos Dados como referencial metodológico. Os dados são coletados por meio de entrevista com as crianças, mediada por uma sessão de Brinquedo Terapêutico. A análise preliminar dos dados permitiu compreender que ter anemia falciforme é uma vivência triste para a criança, porque, além de ser permeada pela dor, ela se percebe impotente frente ao sofrimento, reconhece seus sintomas, compreende a necessidade do tratamento, considerando-o apenas paliativo; que a família é um importante suporte, e o hospital, uma referência.Nota previa de una investigación que tiene como objetivo comprender el significado de tener anemia falciforme para niños de 3 a 12 años. Investigación cualitativa anclada en el Interaccionismo Simbólico como referencia teórica y en la Teoría Fundamentada en los datos como referencia metodológica. Los datos son recolectados por medio de entrevista con los niños, mediada por una sesión de Juguete Terapéutico. El análisis preliminar de los datos permitió comprender que tener anemia falciforme es una vivencia triste para el niño, porque además de ser atravesada por el dolor, ella se percibe impotente frente al sufrimiento, reconoce los síntomas, comprende la necesidad de tratamiento, considerándolo solamente paliativo, que la familia es un importante soporte y el hospital una referencia.Advance notice of a study aimed at understanding the significance of having sickle cell anemia for children 3 to 12 years old. It is a qualitative research grounded in Symbolic Interactionism as a theoretical perspective, and in Grounded Theory as a research method. The data have been collected through interview with the children by using therapeutic play

Anemia em catadores de material reciclável que utilizam carrinho de propulsão humana no município de Santos Anemia in recyclable waste pickers using human driven pushcarts in the city of Santos, southeastern Brazil

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Mauro Abrahão Rozman

2010-06-01

Full Text Available OBJETIVO: Estimar a prevalência de anemia e analisar os fatores de risco a ela associados nos catadores de material reciclável que utilizam carrinho de propulsão humana do município de Santos - São Paulo. MÉTODO: Estudo transversal com 253 catadores foi realizado em julho de 2005. A coleta de informações foi feita por meio de questionário com informações sobre características individuais, ocupacionais e dietéticas. Foi realizada avaliação antropométrica e coletado sangue venoso para hemograma completo e sorologias de HIV, HCV, HBV e sífilis. A análise estatística foi feita por análise uni e multivariada (regressão logística, relacionando a anemia aos fatores de risco. RESULTADOS: A prevalência de anemia foi de 38,3%. As variáveis que mostraram associação independente com anemia no modelo multivariado foram: sexo (OR 4,11; IC95%: 1,56-10,87, infecção pelo HIV (OR 9,23; IC95%: 2,93-29,1, IMC (OR 0,21; IC95%: 0,07-0,64, anos de trabalho como catador (OR 4,54; IC95%: 1,29-16,0, consumo de leite (OR 0,36; IC95%: 0,16-0,81 e de proteína animal (OR 0,39; IC95%: 0,15-0,97. CONCLUSÃO: A prevalência de anemia entre catadores de material reciclável é elevada mesmo após a obrigatoriedade de adição de ferro nas farinhas de trigo e milho. Os catadores são excluídos das ações de proteção à saúde do trabalhador, previstas na legislação. Ações de saúde dirigidas a essa categoria profissional devem ser implementadas, garantindo a acessibilidade aos serviços de saúde.OBJECTIVE: To assess the prevalence of anemia and describe associated risk factors in recyclable waste pickers using human-driven pushcarts in the city of Santos. METHODS: A cross-sectional study including 253 recyclable waste pickers was conducted in the city of Santos, southeastern Brazil, in July 2005. A questionnaire was used to collect information about individual, occupational, and dietary factors. All subjects underwent an anthropometric

The incidence of gastrointestinal pathology and subsequent anemia in young men presenting with iron deficiency without anemia.

Science.gov (United States)

Carter, Dan; Bardan, Eytan; Derazne, Estela; Tzur, Dorit; Avidan, Benjamin

2016-10-01

The etiology of iron deficiency (ID) without anemia in young men is unclear, and there are no evidence-based recommendations for the required gastrointestinal (GI) evaluation. The aims of this study were to examine the incidence of significant GI pathology and the development of anemia during the follow-up of young men presenting with ID, but without anemia. All young men (18-30 years) who served in the Israel Defense Forces during the years 2005-2013 and had at least a single laboratory test indicative of ID without anemia were followed until the diagnosis of significant GI pathology or discharge from military service. The study population included 2061 young men (mean age 20.7±1.8). During follow-up of 3150 person years, significant GI pathologies were diagnosed in 39 patients: inflammatory bowel disease in 25 (1.2%), celiac disease in 8 (0.4%), and peptic disease in 4 (0.1%). No cases of GI-related cancer were diagnosed. ID anemia developed during follow-up in 203 (9.8%). Lower baseline hemoglobin levels, lower ferritin levels, and younger age at diagnosis were more common among those who developed anemia. The development of anemia was a predisposing factor for the diagnosis of GI pathology (risk ratio=3.60, 95% confidence interval 1.34-8.32, P=0.012). Significant GI pathology is very uncommon in young men presenting with ID. Overt anemia developed in close to 10% of the study cohort. Therefore, we advise simple GI evaluation (celiac serology, C-reactive protein or fecal calprotectin, and urease breath test) as well as follow-up in this population.

Enteroparasitoses, Anemia e Estado Nutricional em Grávidas Atendidas em Serviço Público de Saúde Intestinal Parasites, Anemia and Nutritional Status in Pregnant Women in a Public Health Care Unit

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Ariani Impieri de Souza

2002-05-01

Full Text Available Objetivos: estimar a freqüência de enteroparasitoses em gestantes de pré-natal de baixo risco e sua associação com anemia, estado nutricional, escolaridade e saneamento (fossa sanitária no domicílio. Métodos: a partir de amostra de 316 gestantes que iniciaram o pré-natal de baixo risco do ambulatório de pré-natal do Instituto Materno Infantil de Pernambuco (IMIP no período de maio de 2000 a julho de 2001, determinaram-se, por meio de um desenho de corte transversal, as freqüências de enteroparasitoses (método Hoffman, em única amostra e de anemia (Hb Purpose: to determine the frequency of enteroparasitoses in a group of pregnant women undergoing low-risk antenatal care and their association with anemia, maternal nutritional status, schooling and the existence of a bathroom in the home. Methods: to a sample of pregnant women who had begun low-risk antenatal care at IMIP's Maternal Health Care Center between May 2000 and July 2001, a cross-sectional design was applied to determine the frequencies of enteroparasitoses (Hoffman method, in a single sample and anemia (Hb <11.0 g/dL, nutritional status (through BMI standardized for stage of pregnancy and social indicators (schooling and the existence of a bathroom in the home. Results: in a sample of 316 pregnant women, a rate of 37.4% enteroparasitosis was detected, of which 31.6% was infestation by a single parasite. The most commonly found parasite species were Entamoeba histolytica (13.3% and Ascaris lumbricoides (12.0%. Anemia was detected in 55.4% of the pregnant women, malnutrition in 25.0% and overweight or obesity in 24.1%. There was a statistically significant association between enteroparasitosis and schooling. However, no association of, enteroparasitosis, anemia, maternal nutritional status with the existence of a bathroom in the home was noted. Conclusions: The prevalence of enteroparasitoses and anemia is high, albeit without any association of the two conditions, while

Prevalencia de anemia en gestantes en un área de salud

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Marianela de la C Prendes Labrada

2000-02-01

Full Text Available Se realizó un estudio descriptivo de corte transversal en el período comprendido entre enero y septiembre de 1998 en el área del Policlínico Santos Suárez con el objetivo de determinar la prevalencia de la anemia en gestantes, su relación con la edad, el estado nutricional materno y el peso al nacer. La muestra estuvo constituida por las 209 gestantes que se captaron en este período. Se realizó revisión de las historias clínicas obstétricas y los datos se recogieron en planilla confeccionada al efecto, se utilizó el cálculo porcentual para su procesamiento. La prevalencia de la anemia en las embarazadas estudiadas fue del 64,59 %, el 83,74 % tenían entre 20 y 35 años. Las gestantes con valoración ponderal inicial (V.P.I. peso bajo I-II-III-IV y peso adecuado desarrollaron anemia con mayor frecuencia. Predominó la hemoglobina entre 109-100 g/l en los 3 trimestres de la gestación independientemente de la V.P.I. La mayoría de las gestantes anémicas (80,74 % se trataron con tabletas prenatales solamente y aportaron recién nacidos con un peso menor de 3 000 gA descriptive cross-sectional study was conducted between January and September, 1998, in the area of the "Santos Suárez" Polyclinic in order to determine the prevalence of anemia in pregnant women, its relatioship with age, maternal nutritional state and birth weight. The sample was composed of 209 pregnant women that were caught in this period. The obstetric medical histories were reviewed and the data were collected in forms created to this end. The percentage calculstion was used for their processing. The prevalence of anemia among the studied expectants was of 64. 59 %. 83.74 % were between 20 and 35 years old. Those pregnant women with initial weighted assessment (IWA considered as low weight I-II-III-IV an adequate weight developed anemia with higher frequency. Haemoglobine from 109 to 100 g/L predominated during the 3 trimesters of pregnancy independently of I

Caligus rogercresseyi: posible vector en la transmisión horizontal del virus de la anemia infecciosa del salmón (ISAv

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Karin Oelckers

2015-05-01

Full Text Available Chile el año 2007 se convirtió en el segundo país productor de salmónidos a nivel mundial. Al año siguiente la industria salmonera nacional comenzó a experimentar una severa crisis sanitaria producida por el virus causante de la anemia infecciosa del salmón. Este virus se presentó por primera vez en Noruega (1984, luego en Canadá, Escocia, Islas Faroe, Estados Unidos y Chile (2007. La anemia infecciosa del salmón (ISA, es una enfermedad altamente contagiosa entre los peces, producida por un virus de la familia Orthomyxoviridae. La especie más vulnerable a este virus es el salmón del Atlántico (Salmo salar. La plaga parasitaria producida por el piojo de mar, Caligus rogercresseyi, copépodo ectoparásito, ha ido en aumento lo que favorece el contagio de enfermedades bacterianas y virales. De todas las especies cultivadas en Chile, el salmón del Atlántico, S. salar es una de las especies más susceptibles de ser infestadas por C. rogercresseyi. Durante el 2006, la industria presentó un aumento significativo en las tasas de infestación por Caligus; luego en el 2007, aparecieron brotes del virus ISA. En Noruega, se ha demostrado que el piojo de mar, Lepeophtherius salmonis puede tener un rol como vector en la transmisión del virus ISA, por lo que el objetivo de este trabajo fue determinar si C. rogercresseyi es un vector de transmisión del virus ISA en el salmón del Atlántico, cultivado en el sur de Chile.

Uncinariasis como causa de anemia ferropénica en población penitenciaria

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A. Rodríguez-Guardado

2013-10-01

Full Text Available Presentamos un caso clínico de parasitosis por uncinarias en un paciente de origen español, interno en el centro penitenciario, que residió en Brasil. El diagnóstico se estableció a partir de un cuadro de astenia progresiva con una importante pérdida de peso. La analítica mostró anemia ferropénica y eosinofilia, por lo que fue ingresado para estudio hospitalario por Medicina interna, encontrándose huevos de uncinarias en heces. Se realizó tratamiento con Albendazol y hierro consiguiéndose la curación clínica,la normalización de los parámetros bioquímicos y la negativización de las muestras de heces. Creemos que es necesario por parte del médico de prisiones pensar en esta y otras parasitosis ante internos procedentes de países tropicales, donde estas helmintosis son endémicas. Además, quizá sería oportuno por parte de Sanidad Penitenciaria instaurar programas de cribado de parásitos en población inmigrante, incluso si son asintomáticos.

The Evidence-Based Evaluation of Iron Deficiency Anemia.

Science.gov (United States)

Hempel, Eliana V; Bollard, Edward R

2016-09-01

Anemia is a prevalent disease with multiple possible etiologies and resultant complications. Iron deficiency anemia is a common cause of anemia and is typically due to insufficient intake, poor absorption, or overt or occult blood loss. Distinguishing iron deficiency from other causes of anemia is integral to initiating the appropriate treatment. In addition, identifying the underlying cause of iron deficiency is also necessary to help guide management of these patients. We review the key components to an evidence-based, cost-conscious evaluation of suspected iron deficiency anemia. Copyright © 2016 Elsevier Inc. All rights reserved.

Anemia

Science.gov (United States)

... a hemoglobin value of less than 13.5 gm/dl in a man or less than 12.0 gm/dl in a woman. Normal values for children ... types of anemia cannot be prevented, eating healthy foods can help you avoid both iron-and vitamin- ...

Anemia em adolescentes segundo maturação sexual Anemia among adolescents according to sexual maturation

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Bianca Assunção Iuliano

2004-03-01

Full Text Available OBJETIVO: Verificar a prevalência de anemia em adolescentes (hemoglobina0,05. Observou-se aparente aumento do nível médio de hemoglobina com o desenvolvimento do adolescente. Detectou-se anemia em 11,0% dos adolescentes, a maioria na fase púbere, classificada como ''prevalência leve'' segundo a World Health Organization. Não foi encontrada associação entre indicadores sociais e anemia. CONCLUSÃO: O estudo apontou baixa prevalência de anemia, mas acima do esperado entre púberes de escola particular e indica tendência de aumento dos níveis de hemoglobina com o desenvolvimento sexual dos adolescentes. Devem ser realizados novos estudos de prevalência de anemia para se determinar sua causa entre adolescentes de diferentes níveis socioeconômicos.OBJECTIVE: To assess the prevalence of anemia (hemoglobin level <12g/dL in adolescents, according to their sexual maturation stage. METHODS: A cross-sectional study was conducted with all adolescents enrolled in 5th - 8th grades in a private school in the city of São Paulo. Their hemoglobin level was measured (using Hemocue® and sexual development was self-evaluated (with the aid of pictures of the maturation stages proposed by Tanner. The social indicators evaluated were the per capita family income and maternal schooling. Student t test and non-parametric Kruskal-Wallis test were used for mean comparison and Chi-square-test for associations (p<0.05. RESULTS: We analyzed 118 students, of which 66.9% were females (aged 12.2±1.13 years and 33.1% were males (aged 12.0±1.18 years. The mean hemoglobin level was 13.2±1.08 g/dL for females and 13.3±1.21 g/dL for males, with no significant difference. An apparent increase in the mean hemoglobin level was verified along with sexual development of the adolescents. Anemia was detected in 11% of them, most in the pubertal stage, which is classified by the World Health Organization as ''mild prevalence''. No association was found between social

Management of Anemia of Inflammation in the Elderly

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Antonio Macciò

2012-01-01

Full Text Available Anemia of any degree is recognized as a significant independent contributor to morbidity, mortality, and frailty in elderly patients. Among the broad types of anemia in the elderly a peculiar role seems to be played by the anemia associated with chronic inflammation, which remains the most complex form of anemia to treat. The origin of this nonspecific inflammation in the elderly has not yet been clarified. It seems more plausible that the oxidative stress that accompanies ageing is the real cause of chronic inflammation of the elderly and that the same oxidative stress is actually a major cause of this anemia. The erythropoietic agents have the potential to play a therapeutic role in this patient population. Despite some promising results, rHuEPO does not have a specific indication for the treatment of anemia in the elderly. Moreover, concerns about their side effects have spurred the search for alternatives. Considering the etiopathogenetic mechanisms of anemia of inflammation in the elderly population, an integrated nutritional/dietetic approach with nutraceuticals that can manipulate oxidative stress and related inflammation may prevent the onset of this anemia and its negative impact on patients’ performance and quality of life.

Management of Anemia of Inflammation in the Elderly

Science.gov (United States)

Macciò, Antonio; Madeddu, Clelia

2012-01-01

Anemia of any degree is recognized as a significant independent contributor to morbidity, mortality, and frailty in elderly patients. Among the broad types of anemia in the elderly a peculiar role seems to be played by the anemia associated with chronic inflammation, which remains the most complex form of anemia to treat. The origin of this nonspecific inflammation in the elderly has not yet been clarified. It seems more plausible that the oxidative stress that accompanies ageing is the real cause of chronic inflammation of the elderly and that the same oxidative stress is actually a major cause of this anemia. The erythropoietic agents have the potential to play a therapeutic role in this patient population. Despite some promising results, rHuEPO does not have a specific indication for the treatment of anemia in the elderly. Moreover, concerns about their side effects have spurred the search for alternatives. Considering the etiopathogenetic mechanisms of anemia of inflammation in the elderly population, an integrated nutritional/dietetic approach with nutraceuticals that can manipulate oxidative stress and related inflammation may prevent the onset of this anemia and its negative impact on patients' performance and quality of life. PMID:23091709

Prevalência e fatores associados à ocorrência de anemia entre menores de seis anos de idade em Pelotas, RS Prevalence of anemia and associated factors among children under six years of age in Pelotas, South Brazil

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Iná dos Santos

2004-12-01

Full Text Available OBJETIVOS: Determinar a prevalência e investigar fatores associados à ocorrência de anemia entre menores de seis anos de idade atendidos pela Pastoral da Criança em Pelotas, RS. MÉTODOS: Na fase de rastreamento de uma intervenção nutricional, as crianças foram avaliadas através de estudo transversal. No domicílio, após consentimento informado, a mãe foi entrevistada, sendo coletadas informações sobre características demográficas e socioeconômicas da família, saúde da criança, características ao nascer, amamentação e freqüência semanal de consumo de alimentos. As crianças foram pesadas e medidas. Foi coletada uma amostra de sangue capilar da polpa digital em microcuveta e a leitura da concentração de hemoglobina foi feita em fotômetro portátil (Hemocue. Considerou-se como tendo anemia quando a concentração de hemoglobina era inferior a 11 g/dl. Por se tratar de desfecho freqüente, a associação com as variáveis independentes foi analisada por regressão de Poisson. A análise obedeceu a modelo hierárquico previamente definido. RESULTADOS: Foram identificadas 362 crianças menores de seis anos, sendo a hemoglobina dosada em 304 (84,0% delas. A prevalência de anemia foi de 53,0% (IC95% 47,2% - 58,7%. Os fatores de risco foram a menor idade da criança, cor não branca, presença de família numerosa e classe social E (em comparação à D. A disponibilidade de água encanada dentro de casa e o maior peso ao nascer mostraram-se fatores protetores. CONCLUSÕES: os achados deste estudo mostram uma alta prevalência de anemia entre as crianças alvo da ação da Pastoral da Criança, bem como a presença de diversos fatores de risco e poucos fatores de proteção, o que mostra a necessidade de intervenções preventivas.OBJECTIVES: to determine the prevalence of and investigate factors associated with anemia among children under six years of age, assisted by the Pastoral da Criança in Pelotas, South Brazil. METHODS

Socio-economic and demographic determinants of childhood anemia

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Sankar Goswmai

2015-10-01

Full Text Available ABSTRACT OBJECTIVE: To evaluate socio-economic and demographic determinants of anemia among Indian children aged 6-59 months. METHODS: Statistical analysis was performed on the cross-sectional weighted sample of 40,885 children from 2005 to 2006 National Family Health Survey by using multinomial logistic regression to assess the significance of some risk factors in different degrees of child anemia. Anemia was diagnosed by World Health Organization (WHO cut-off points on hemoglobin level. Pearson's chi-squared test was applied to justify the associations of anemia with different categories of the study population. RESULTS: The prevalence of anemia was 69.5%; 26.2% mild, 40.4% moderate, and 2.9% severe anemia. Overall prevalence rate, along with mild and moderate cases, showed an increasing trend up to 2 years of age and then decreased. Rural children had a higher prevalence rate. Of 28 Indian states in the study, 10 states showed very high prevalence, the highest being Bihar (77.9%. Higher birth order, high index of poverty, low level of maternal education, mother's anemia, non-intake of iron supplements during pregnancy, and vegetarian mother increased the risks of all types of anemia among children (p < 0.05. Christian population was at lower risk; and Scheduled Caste, Scheduled Tribe, and Other Backward Class categories were at higher risk of anemia. CONCLUSION: The results suggest a need for proper planning and implementation of preventive measures to combat child anemia. Economically under-privileged groups, maternal nutrition and education, and birth control measures should be priorities in the programs.

Management of Iron Deficiency Anemia

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Jimenez, Kristine; Kulnigg-Dabsch, Stefanie

2015-01-01

Anemia affects one-fourth of the world’s population, and iron deficiency is the predominant cause. Anemia is associated with chronic fatigue, impaired cognitive function, and diminished well-being. Patients with iron deficiency anemia of unknown etiology are frequently referred to a gastroenterologist because in the majority of cases the condition has a gastrointestinal origin. Proper management improves quality of life, alleviates the symptoms of iron deficiency, and reduces the need for blood transfusions. Treatment options include oral and intravenous iron therapy; however, the efficacy of oral iron is limited in certain gastrointestinal conditions, such as inflammatory bowel disease, celiac disease, and autoimmune gastritis. This article provides a critical summary of the diagnosis and treatment of iron deficiency anemia. In addition, it includes a management algorithm that can help the clinician determine which patients are in need of further gastrointestinal evaluation. This facilitates the identification and treatment of the underlying condition and avoids the unnecessary use of invasive methods and their associated risks. PMID:27099596

Unexpected Anemia and Reticulocytopenia in an Adolescent With Sickle Cell Anemia Receiving Chronic Transfusion Therapy.

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Blauel, Emily R; Grossmann, Lily T; Vissa, Madhav; Miller, Scott T

2015-10-01

In a patient with sickle cell disease receiving chronic transfusion, exacerbation of anemia with reticulocytopenia must prompt consideration of a delayed hemolytic transfusion reaction with hyperhemolysis, as further transfusion may worsen this condition; definitive diagnosis is sometimes difficult. Anemia evolving during parvovirus B19-induced erythroid hypoplasia (transient aplastic crisis) should be attenuated in chronic transfusion patients due to superior survival of transfused over endogenous red blood cells. A 16-year-old with sickle cell disease receiving chronic transfusion of modified intensity (goal to maintain hemoglobin S<50%) who developed symptomatic anemia with reticulocytopenia was later shown to have had transient aplastic crisis.

Genetics Home Reference: thiamine-responsive megaloblastic anemia syndrome

Science.gov (United States)

... Thiamine-responsive megaloblastic anemia syndrome Thiamine-responsive megaloblastic anemia syndrome Printable PDF Open All Close All Enable ... the expand/collapse boxes. Description Thiamine-responsive megaloblastic anemia syndrome is a rare condition characterized by hearing ...

9 CFR 311.34 - Anemia.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Anemia. 311.34 Section 311.34 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION... CERTIFICATION DISPOSAL OF DISEASED OR OTHERWISE ADULTERATED CARCASSES AND PARTS § 311.34 Anemia. Carcasses of...

Family structure and child anemia in Mexico.

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Schmeer, Kammi K

2013-10-01

Utilizing longitudinal data from the nationally-representative Mexico Family Life Survey, this study assesses the association between family structure and iron-deficient anemia among children ages 3-12 in Mexico. The longitudinal models (n = 4649), which control for baseline anemia status and allow for consideration of family structure transitions, suggest that children living in stable-cohabiting and single-mother families and those who have recently experienced a parental union dissolution have higher odds of anemia than those in stable-married, father-present family structures. Interaction effects indicate that unmarried family contexts have stronger associations with anemia in older children (over age five); and, that the negative effects of parental union dissolution are exacerbated in poorer households. Resident maternal grandparents have a significant beneficial effect on child anemia independent of parental family structure. These results highlight the importance of family structure for child micronutrient deficiencies and suggest that understanding social processes within households may be critical to preventing child anemia in Mexico. Copyright © 2012 Elsevier Ltd. All rights reserved.

Tissue Factor and Thrombin in Sickle Cell Anemia

OpenAIRE

Chantrathammachart, Pichika; Pawlinski, Rafal

2012-01-01

Sickle cell anemia is an inherited hematologic disorder associated with hemolytic and vaso-occlusive complications. An activation of coagulation is also a prominent feature of sickle cell anemia. Growing evidence indicates that coagulation may contribute to the inflammation and vascular injury in sickle cell anemia. This review focuses on tissue factor expression and its contribution to the activation of coagulation, thrombosis and vascular inflammation in sickle cell anemia.

Iron Deficiency, Anemia and Mortality in Renal Transplant Recipients

NARCIS (Netherlands)

Eisenga, Michele F.; Minovic, Isidor; Berger, Stefan P.; Kootstra-Ros, Jenny E.; van den Berg, Else; Riphagen, Ineke J.; Navis, Gerjan; van der Meer, Peter; Bakker, Stephan J. L.; Gaillard, Carlo A. J. M.

Anemia, iron deficiency anemia (IDA), and iron deficiency (ID) are highly prevalent in renal transplant recipients (RTR). Anemia is associated with poor outcome, but the role of ID is unknown. Therefore, we aimed to investigate the association of ID, irrespective of anemia, with all-cause mortality

Iron Deficiency, Anemia and Mortality in Renal Transplant Recipients

NARCIS (Netherlands)

Eisenga, Michele F.; Minovic, Isidor; Berger, Stefan P; Kootstra-Ros, Jenny E.; van den Berg, Else; Riphagen, Ineke J.; Navis, Gerjan J.; Van der Meer, Peter; Bakker, Stephan J. L.; Gaillard, Carlo A. J. M.

2016-01-01

Anemia, iron deficiency anemia (IDA), and iron deficiency (ID) are highly prevalent in renal transplant recipients (RTR). Anemia is associated with poor outcome, but the role of ID is unknown. Therefore, we aimed to investigate the association of ID, irrespective of anemia, with all-cause mortality

Multidisciplinary approach to anemia

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Anca Ghiațău

2015-08-01

Full Text Available Introduction: We present the case of a 65 years- old woman who was admitted with a severe macrocytic anemia Hb= 5.7g/dl and diffuse bone pain. Biologically she has moderate thrombocytopenia 35 000/µl, a hepatic cytolysis and cholestatic syndrome. Material and method: The patient was extensively evaluated before presentation for a mild iron - deficiency anemia for which she underwent endoscopic examination of the upper and lower gastrointestinal tract- normal. The bone marrow aspiration on admission revealed a marked hyperplasia of the erythroblastic line with ~50% basophilic erythroblasts suggesting a regenerative erythroid hyperplasia. These changes along with the marked reticulocytosis on the peripheral blood smear oriented us towards a hemolytic anemia; Folic acid, vitamin B12, autoimmune tests and hemolytic tests were all normal. We continued the investigations with a thoraco-abdominopelvic computed tomography which identified diffuse demineralization, vertebral compactation and pelvic stress fractures. The breast examination revealed a right breast nodule, but the breast ultrasonography pleaded for benignity. Lacking a clear definitive diagnosis we decided to perform a bone marrow biopsy. Results: The osteo- medullary biopsy pointed towards a medullar invasion from a lobular mammary carcinoma; In these circumstances we performed an ultrasound guided biopsy of the right mammary lump thus histologically confirming a tumoral invasion of the bone marrow with subsequent anemia. The patient started chemotherapy in the Oncology ward. Conclusion: The particularity of this case consists in the pattern of anemia, which initially seemed iron deficient and afterwards macrocytic – apparently hemolytic and was actually due to the tumoral medullar invasion and also the nonspecific ultrasonographic appearance of the breast tumor.

Flaws in the Spanish Translation of Beginning Readers’ Books (Deficiencias en la traducción al español de libros de lectura inicial

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Sonia Rodríguez Salazar

2016-09-01

Full Text Available This article presents the main results of an analysis of important flaws in the Spanish translation of a number of children’s story books, known as Beginning Readers’ Books. It addresses errors which can affect the children’s process of acquiring reading and writing skills. These deficiencies can be attributed to the translators’ lack of familiarity with the initial reading patterns and their relation to a phonological awareness of Spanish. This study aims to provide initial guidelines for a translation of this sort. Se exponen los principales resultados de un estudio que analiza significativas deficiencias en la traducción al español de varios tomos de cuentos, bajo el título general de Beginning Readers’ Books. Se trata de errores que afectan el proceso de lectoescritura del lector meta. Tales deficiencias se atribuyen al desconocimiento de patrones básicos de lectura y su relación con la conciencia fonológica del español. El estudio tiene como objetivo ofrecer una guía inicial para mejorar este tipo de traducciones.

Factors Associated with Anemia in the Institutionalized Elderly.

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Emanuelle Cruz da Silva

Full Text Available As a common problem in long-term care facilities (LTCFs, anemia affects 25-63% of the elderly. The aim of the present study was to describe the prevalence and characteristics of anemia and its associated factors in the institutionalized elderly. The cross-sectional study was carried out with three hundred thirteen individuals aged ≥ 60 years, of both genders, living in long-term care facilities for the elderly in Salvador, Bahia, Brazil. Poisson regression (PR with robust variance estimates was used to assess the factors related to anemia. The prevalence of anemia was 38%. Mild anemia was predominant in both genders (male: 26.8%; female: 21.1%, as normocytic and normochromic anemia, with no anisocytosis (69.75%. Anemia was associated with thinness (PR: 1.68; 95% CI: 1.04-2.72 and with moderate (PR: 1.98; 95% CI: 1.07-3.63 and total (PR: 2.61; 95% CI: 1.34-5.07 dependence in the final model. Severe dependence exhibited borderline significance (PR: 1.94; 95% CI: 1.00-3.77. The prevalence of anemia was high in the institutionalized elderly in both genders, with characteristics suggesting chronic diseases as the causal factor, and the frequency of occurrence was higher in thinness elderly with moderate to total dependence.

Encefalitis del tallo cerebral y mielitis por Listeria monocytogenes

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Aracelly Castro

2013-09-01

Full Text Available La romboencefalitis por Listeria monocytogenes es una presentación poco común de la listeriosis del sistema nervioso central; sin embargo, es la presentación más común en personas inmunocompetentes. Aun más rara es la combinación de romboencefalitis con mielitis causada por L. monocytogenes; no obstante, en este artículo se reporta un caso de encefalitis del tallo y mielitis grave en un paciente sin compromiso del sistema inmunitario. Se presenta un paciente de 21 años de edad, sin deficiencias del sistema inmunitario, que consumió productos lácteos no pasteurizados y, posteriormente, presentó un cuadro de cefalea, vómito, deterioro de su estado general y, finalmente, alteración del estado de conciencia y muerte. Consultó al Instituto Neurológico de Colombia y se hizo diagnóstico de encefalitis del tallo y mielitis por L. monocytogenes. Se discuten las diferencias entre el caso presentado y los reportados en la literatura científica. Ante un paciente con signos de compromiso del tallo cerebral, de posible origen infeccioso, es prudente iniciar tratamiento antibiótico para L. monocytogenes y, en caso de poca respuesta, escalar rápidamente en dicho tratamiento. También lo es extender el estudio radiológico hacia la columna vertebral, con el fin de descartar compromiso de la médula espinal.   doi: http://dx.doi.org/10.7705/biomedica.v33i3.1482

Efetividade da suplementação diária ou semanal com ferro na prevenção da anemia em lactentes Efectividad en el suplemento diario o semanal de hierro en la prevención de anemia en lactantes Effectiveness of daily and weekly iron supplementation in the prevention of anemia in infants

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Elyne Montenegro Engstrom

2008-10-01

Full Text Available OBJETIVO: Avaliar a efetividade da suplementação universal profilática com sulfato ferroso, em administração diária ou semanal, na prevenção da anemia em lactentes. MÉTODOS: Ensaio de campo randomizado com crianças de seis a 12 meses de idade, atendidas em unidades básicas de saúde do município do Rio de Janeiro, em 2004-2005. Foram formadas três coortes concorrentes com suplementação universal com sulfato ferroso com grupos: diário (n=150; 12,5mgFe/dia, semanal (n=147; 25mgFe/semana e controle (n=94. A intervenção durou 24 semanas e foi acompanhada por ações educativas promotoras de adesão. A concentração de hemoglobina sérica foi analisada segundo sua distribuição, média e prevalência de anemia (HbOBJETIVO: Evaluar la efectividad del suplemento universal profiláctico con sulfato ferroso, en administración diaria o semanal, en la prevención de la anemia en lactantes. MÉTODOS: Se realizo un ensayo de campo aleatorio con niños de seis a 12 meses de edad, atendidos en unidades básicas de salud del municipio de Río de Janeiro (Sureste de Brasil, en 2004-2005. Se formaron tres cohortes coincidentes con suplemento universal con sulfato ferroso con grupos: diario (n=150; 12,5mgFe/dia, semanal (n=147; 25mgFe/semana y control (n=94. La intervención duró 24 semanas y fue acompañada por acciones educativas promotoras de adhesión. La concentración de hemoglobina sérica fue analizada de acuerdo a su distribución, promedio y prevalencia de anemia (HbOBJECTIVE: To evaluate the effectiveness of universal prophylactic targeting with iron sulfate on daily or weekly basis in the prevention of anemia in infants. METHODS: Randomized clinical field trial with children between ages six and 12 months seen at primary health care units in the municipality of Rio de Janeiro, Brazil, between 2004 and 2005. Three concurrent cohorts were compared: daily group (n=150; 12.5mg Fe/day; weekly group (n=147; 25mg Fe/week and control

Genetics Home Reference: congenital dyserythropoietic anemia

Science.gov (United States)

... Facebook Twitter Home Health Conditions CDA Congenital dyserythropoietic anemia Printable PDF Open All Close All Enable Javascript ... view the expand/collapse boxes. Description Congenital dyserythropoietic anemia ( CDA ) is an inherited blood disorder that affects ...

FastStats: Anemia or Iron Deficiency

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... this? Submit What's this? Submit Button NCHS Home Anemia or Iron Deficiency Recommend on Facebook Tweet Share ... visits Number of visits to emergency departments with anemia as the primary hospital discharge diagnosis: 188,000 ...

Treatment of anemia with darbepoetin alfa in systolic heart failure

DEFF Research Database (Denmark)

Swedberg, Karl; Young, James B; Anand, Inder S

2013-01-01

Patients with systolic heart failure and anemia have worse symptoms, functional capacity, and outcomes than those without anemia. We evaluated the effects of darbepoetin alfa on clinical outcomes in patients with systolic heart failure and anemia.......Patients with systolic heart failure and anemia have worse symptoms, functional capacity, and outcomes than those without anemia. We evaluated the effects of darbepoetin alfa on clinical outcomes in patients with systolic heart failure and anemia....

Prevalence and Correlates of Maternal Anemia in Rural Sidama ...

African Journals Online (AJOL)

In order to assess the prevalence and correlates of prenatal anemia, a survey was conducted among 700 randomly selected pregnant women in rural Sidama, Southern Ethiopia. The prevalences of anemia, Iron Deficiency (ID) and ID anemia were 31.6%, 17.4% and 8.7%, respectively. The burden of anemia was ...

Correction of anemia in pregnancy

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Analía Cánepa

2015-11-01

Se observó que en el 50% de las pacientes estudiadas no se logró corregir la anemia. Concluimos que existe una dificultad en la corrección de la anemia y una necesidad de realizar futuros estudios que permitan conocer las causas de este problema e implementar acciones en base a ellas.

Importância da reabsorção do ferro da hemorragia intestinal provocada pela ação dos vermes na progressão da anemia The importance of iron reabsorption in intestinal hemorrhage caused by worms in the course of anemia

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Victorio Maspes

1979-12-01

Full Text Available Foram estudados 10 doentes, portadores de anemia ancilostomótica e de grande parasitose. Foram determinados alguns parâmetros hematológicos como dosagem de hemoglobina, contagem de hemácias, hematócrito, volume corpuscular médio, hemoglobina corpuscular média, ferro sérico e siderofilina. Foram estudados o volume da perda de sangue intestinal, o ferro perdido nesta hemorragia e eliminado nas fezes, e o ferro reaborvido da hemorragia intestinal. Conclui-se que a reabsorção do ferro da hemoglobina por dia no tubo digestivo é de suma importância no retardamento da instalação da anemia ferropriva, causada pela parasitose ancilostomótica.Ten patients presenting ancylostomotic anemia and a high rate of parasitosis were submitted to several hematologic determinations: hemoglobin level, erythrocyte count, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, serum iron level, and transferrin. In addition, measurements were made of the blood volume lost by intestinal bleeding, of iron loss through hemorrhage and in feus, and of iron reabsorption from intestinal bleeding. The main reason for the late appearance of iron deficiency anemia in ancylostomiasis is the high degree of dally iron absorption in the digestive tract, originating from hemoglobin breakdown.

CLINICO PATHOLOGICAL STUDY OF PATTERNS OF ANEMIA DURING PREGNANCY

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Chamakuri

2015-10-01

Full Text Available INTRODUCTION: Anemia is defined as haemoglobin level in the blood below the lower extreme of the normal range for the age and sex of the individual. According to WHO, in developing countries the prevalence of anemia among pregnant women averages 60%, ranging between 35 to 100% among different regions of the world. A hemoglobin concentration below 11.0g/dl or packed cell volume (PCV of less than 33.0% is regarded as anemia during pregnancy by the WHO. It occurs in 40 - 80% of the pregnant women. Iron and folic acid defici encies, malaria, intestinal parasitic infections and hemoglobinopathies are the principal causes of anemia in pregnancy. Predisposing factors include young age, grand multiparity, low socioeconomic status, illiteracy, ignorance and short intervals of pregn ancy. AIM AND OBJECTIVES: 1. To study various patterns of anemia in pregnant women having haemoglobin level < 11 gm%. 2. To determine the most common pattern of anemia in pregnancy based on red cell morphology. MATERIALS AND METHODS: This study is a prospe ctive study over a period of one year from September 2014 to August 2015 in the department of pathology, Andhra medical college, Visakhapatnam . The study was conducted on 120 pregnant women whose haemoglobin level is < 11 gm/dl. All the haemotological parameters & peripheral blood smear stained by Leishman’s stain were evaluated. Complete clinical & obstetric history was recorded. Socioeconomic status was also noted. RESULTS: Out of 120 cases of anemia, we found 47 patie nts (39.1% having dimorphic anemia, 36(30% – microcytic hypochromic anemia, 23(19.1% - normocytic hypochromic anemia, 11(9.16% - sickle cell anemia and 1(0.83% case of pancytopenia. Maximum cases were seen in the age group of 21 - 30 years. 52 cases (43. 3% were primigravida and remaining 68 cases (56.6% were gravida two to four. 20 cases (16.6% were diagnosed in the first trimester, 38 cases (31.6% in the second trimester & 62 cases (51.6s% in the

Correlative study on anemia and radiotherapy effects in nasopharyngeal carcinoma

International Nuclear Information System (INIS)

Chen Jinsheng; Jiang Yuanshi; Cao Xibiao; Zhan Yongzhong; Yang Liye; Chen Jianxiu; Chen Chengwu; Li Yang

2003-01-01

Objective: To study the effect of oxygen-carrying ability of blood efficacy of radiotherapy for patients with nasopharyngeal carcinoma. Methods: Altogether 161 cases of patients with nasopharyngeal carcinoma were classified according to severity of anemia, and Hb, RBC, MCH, HCT, MCV, MCHC and RDW were tested before, during and after radiotherapy. The patients were followed-up for up to 5 years, the relationship and mechanism among anemia, radiotherapy effects and survival rate was discussed. Results: The survival rate between anemia group and non-anemia group was different significantly (P<0.05). Anemia before radiotherapy, anemia appearance or anemia deterioration during radiotherapy were sensitive factors affecting radiotherapy results. The anemia more severe, the radiotherapy worse. Conclusion: Anemia-hypohemoglobinemia leads to decrease of oxygen-carrying capacity of blood, resulting in oxygen deficiency of tumor cells and their radiotherapy resistance. Therefore this method is worthy of further studies

Aplastic anemia due to radiation

International Nuclear Information System (INIS)

Sakai, Kunio; Saito, Akira

1978-01-01

The relationship between radiation exposure and aplastic anemia, clarified previously, is discussed. When persons such as radiological technicians receive whole-body irradiation in rather large doses, it is possible that aplastic anemia will result later on. However, this is difficult to determine because the irradiated region is limited despite large doses of radiation. (Bell, E.)

Prevalence of Anemia in Latin America and the Caribbean.

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Mujica-Coopman, María F; Brito, Alex; López de Romaña, Daniel; Ríos-Castillo, Israel; Coris, Héctor; Olivares, Manuel

2015-06-01

In Latin America and the Caribbean, anemia has been a public health problem that affects mainly women of childbearing age and children under 6 years of age. However, the current prevalence of anemia in this region is unknown. To examine the latest available prevalence data on anemia in Latin America and the Caribbean. A systematic review was conducted in 2011 and updated in 2014. Studies determining the prevalence of anemia conducted in apparently healthy populations with national or regional representativeness were included in the review. The lowest prevalence rates of anemia among children under 6 years of age were found in Chile (4.0%), Costa Rica (4.0%), Argentina (7.6%), and Mexico (19.9%). In Nicaragua, Brazil, Ecuador, El Panama, and Honduras, anemia was a moderate public health problem, with prevalence ranging Salvador, Cuba, Colombia, the Dominican Republic, Peru, from 20.1% to 37.3%. Anemia was a severe public health problem in Guatemala, Haiti, and Bolivia. The prevalence of anemia among women of childbearing age was lowest in Chile (5.1%). In Colombia, El Salvador, Costa Rica, Nicaragua, Ecuador, Mexico, Peru, Honduras, and Argentina, anemia was a mild public health problem, with prevalence ranging from 7.6% to 18.7%. In Guatemala, Brazil, the Dominican Republic, and Bolivia, anemia was a moderate public health problem, with prevalence ranging from 21.4% to 38.3%. Panama and Haiti had the highest reported prevalence rates (40.0% and 45.5%, respectively), and anemia was considered a severe public health problem in those countries. Anemia remains a public health problem in children under 6 years of age and women of childbearing age in most Latin America and Caribbean countries for which data are available.

Evaluación del impacto de los multimicronutrientes en polvo sobre la anemia infantil en tres regiones andinas del Perú

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César V Munayco

Full Text Available Con el objetivo de determinar el impacto de la administración con multimicronutrientes (MMN en polvo sobre la anemia infantil en tres regiones andinas del Perú, se estableció un sistema de vigilancia centinela en 29 establecimientos de Andahuaylas, Ayacucho y Huancavelica, en niños de 6 a 35 meses de edad, a quienes se les indicó MMN por un periodo de 12 meses, entre el 2009 y 2011. Además de los datos sociodemográficos de los menores y las madres, se determinó los niveles de hemoglobina al inicio y al final del estudio. Entre los menores que culminaron la suplementación, la prevalencia de anemia se redujo de 70,2 a 36,6% (p<0,01, y se evidenció que el 55,0% y el 69,1% de niños con anemia leve y moderada al inicio del estudio, la habían superado al término del mismo. Se concluye que la suplementación con MMN en polvo puede ser una estrategia efectiva en la lucha contra la anemia.

Prevalencia de deficiencia de hierro y yodo, y parasitosis en niños de Arandas, Jalisco, México

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Vásquez-Garibay Edgar Manuel; Romero-Velarde Enrique; Nápoles-Rodríguez Francisco; Nuño-Cosío María Eugenia; Trujillo-Contreras Francisco; Sánchez-Mercado Oscar

2002-01-01

Objetivo. Estimar la prevalencia de deficiencia de hierro, yodo y parasitosis en niños que asisten al Instituto Alteño para el Desarrollo de Jalisco (Inadej), Arandas, Jalisco, México. Material y métodos. Estudio transversal efectuado entre 1997 y 1999 con 432 niños de 12 a 120 meses de edad, de nuevo ingreso al Inadej. Se determinaron variables hematológicas, yodo en orina y presencia de parásitos. Se utilizaron las pruebas Ji cuadrada y t de Student en variables no paramétricas y paramétric...

Prevalence of high blood pressure, heart disease, thalassemia, sickle-cell anemia, and iron-deficiency anemia among the UAE adolescent population.

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Barakat-Haddad, Caroline

2013-01-01

This study examined the prevalence of high blood pressure, heart disease, and medical diagnoses in relation to blood disorders, among 6,329 adolescent students (age 15 to 18 years) who reside in the United Arab Emirates (UAE). Findings indicated that the overall prevalence of high blood pressure and heart disease was 1.8% and 1.3%, respectively. Overall, the prevalence for thalassemia, sickle-cell anemia, and iron-deficiency anemia was 0.9%, 1.6%, and 5%, respectively. Bivariate analysis revealed statistically significant differences in the prevalence of high blood pressure among the local and expatriate adolescent population in the Emirate of Sharjah. Similarly, statistically significant differences in the prevalence of iron-deficiency anemia were observed among the local and expatriate population in Abu Dhabi city, the western region of Abu Dhabi, and Al-Ain. Multivariate analysis revealed the following significant predictors of high blood pressure: residing in proximity to industry, nonconventional substance abuse, and age when smoking or exposure to smoking began. Ethnicity was a significant predictor of heart disease, thalassemia, sickle-cell anemia, and iron-deficiency anemia. In addition, predictors of thalassemia included gender (female) and participating in physical activity. Participants diagnosed with sickle-cell anemia and iron-deficiency anemia were more likely to experience different physical activities.

Anemia as a risk factor for childhood asthma

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Ramakrishnan K

2010-01-01

Full Text Available Objective: This prospective-(cohort study was conducted to evaluate whether anemia is a risk factor for childhood asthma. Materials and Methods: Two hundred children in the age group of 2-18 years who attended the Outpatient Department with upper respiratory / lower respiratory tract infections were included in this study. One hundred children with anemia were taken as the study group and another 100, age - and sex-matched children without anemia were taken as the control.They were subjected to complete blood count (CBC C-reactive protein (CRP estimation, Mantoux test and chest X-ray. Pulmonary function tests (PFTs were performed on those above six years showing evidence of asthma. Peripheral smear, serum ferritin and serum iron-binding capacity were estimated for all anemic children. Results: Asthma was present in 74 (74% children in the study group and in 33 (33% children in the control group. Iron-deficiency anemia was present in 85 (85% anemia of chronic infection in 20 (20% and the other five (5% had hemolytic anemia. Anemia was found to be a risk factor for childhood asthma. Conclusion: Anemic children were 5.75 times more susceptible to asthmatic attacks when compared with nonanemic children.

Protrusio acetabuli in sickle-cell anemia

International Nuclear Information System (INIS)

Martinez, S.; Apple, J.S.; Baber, C.; Putman, C.E.; Rosse, W.F.

1984-01-01

Of 155 adults with sickle-cell anemia (SS, SC), radiographs of the pelvis or hip demonstrated protrusio acetabuli on at least one side in 14 (3 men and 11 women), as indicated by projection of the acetabular line medial to the ilio-ischial line. All 14 patients had bone changes attributable to sickle-cell anemia, including marrow hyperplasia and osteonecrosis; however, the severity of femoral or acetabular osteonecrosis did not appear directly related to the protrusion. The authors conclude that sickle-cell anemia can predispose to development of protrusio acetabuli

Eficácia da suplementação de ferro associado ou não à vitamina A no controle da anemia em escolares Efficacy of iron supplementation with or without vitamin A for anemia control

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Rute Cândida Pereira

2007-06-01

Full Text Available Com o objetivo de avaliar a eficácia da suplementação de ferro, associado ou não à vitamina A, na anemia ferropriva, administrado semanalmente, realizou-se ensaio clínico comunitário, randomizado, não controlado por placebo, em 1999. Uma amostra probabilística de 267 escolares de ambos os sexos com 6 a 14 anos de idade foram casualizados em bloco segundo dois tipos de intervenção: um grupo (144 recebeu 200mg de sulfato ferroso com (40mg de ferro elementar e o outro (123 recebeu dose similar de sulfato ferroso associado a 10.000 UI de vitamina A, durante 30 semanas. A prevalência de anemia ao final foi reduzida de 48,4%, para 17,7% (p This study aimed to evaluate the efficacy of weekly iron supplementation with or without vitamin A in the treatment of iron deficiency anemia, using an experimental, randomized, non-placebo-controlled design in 1999. 267 schoolchildren 6 to 14 years of age were randomized to two treatment groups: one group (144 received 200mg iron sulfate alone, with 40mg of elemental iron, while the other (123 received the same iron supplementation dose plus 10,000 IU of vitamin A (both groups for 30 weeks. Final anemia prevalence was reduced from 48.4% to 17.7% (p < 0.001 in the group receiving iron supplementation alone and 58.1% to 14.3% (p < 0.001 in the group receiving iron plus vitamin A. There was no significant difference between the groups at the end of the study according to mean Hb (p = 0.355 and anemia (p = 0.479. There was a significant correction for iron deficiency anemia with weekly iron-alone supplementation, but with no additional advantage of vitamin A. New studies on the synergism between these two micronutrients are recommended.

Magnitude of Anemia at Discharge Increases 30-Day Hospital Readmissions.

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Koch, Colleen G; Li, Liang; Sun, Zhiyuan; Hixson, Eric D; Tang, Anne; Chagin, Kevin; Kattan, Michael; Phillips, Shannon C; Blackstone, Eugene H; Henderson, J Michael

2017-12-01

Anemia during hospitalization is associated with poor health outcomes. Does anemia at discharge place patients at risk for hospital readmission within 30 days of discharge? Our objectives were to examine the prevalence and magnitude of anemia at hospital discharge and determine whether anemia at discharge was associated with 30-day readmissions among a cohort of hospitalizations in a single health care system. From January 1, 2009, to August 31, 2011, there were 152,757 eligible hospitalizations within a single health care system. The endpoint was any hospitalization within 30 days of discharge. The University HealthSystem Consortium's clinical database was used for demographics and comorbidities; hemoglobin values are from the hospitals' electronic medical records, and readmission status was obtained from the University HealthSystem Consortium administrative data systems. Mild anemia was defined as hemoglobin of greater than 11 to less than 12 g/dl in women and greater than 11 to less than 13 g/dl in men; moderate, greater than 9 to less than or equal to 11 g/dl; and severe, less than or equal to 9 g/dl. Logistic regression was used to assess the association of anemia and 30-day readmissions adjusted for demographics, comorbidity, and hospitalization type. Among 152,757 hospitalizations, 72% of patients were discharged with anemia: 31,903 (21%), mild; 52,971 (35%), moderate; and 25,522 (17%), severe. Discharge anemia was associated with severity-dependent increased odds for 30-day hospital readmission compared with those without anemia: for mild anemia, 1.74 (1.65-1.82); moderate anemia, 2.76 (2.64-2.89); and severe anemia, 3.47 (3.30-3.65), P < 0.001. Anemia at discharge is associated with a severity-dependent increased risk for 30-day readmission. A strategy focusing on anemia treatment care paths during index hospitalization offers an opportunity to influence subsequent readmissions.

Anemia e desnutrição em escolares da rede pública do município de Osasco, São Paulo, Brasil

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Maria Lúcia R. Stefanini

Full Text Available Com o objetivo de estimar a prevalência de anemia e conhecer o estado nutricional de escolares, foi realizado um estudo em uma amostra dos alunos ingressantes nas primeiras séries do primeiro grau das escolas públicas de Osasco, município integrante da Região Metropolitana de São Paulo. O diagnóstico de anemia foi feito através da dosagem da concentração de hemoglobina do sangue colhido por punção digital. O nível crítico utilizado para caracterizar a presença de anemia foi o estabelecido pela OMS. O estado nutricional foi avaliado utilizando os indicadores peso/idade e altura/idade expressos em escores Z e a população de referência do NCHS. A prevalência, de anemia encontrada foi de 51%n. Houve diferença nos níveis de prevalência quanto à localização geográfica das escolas, sendo maior (56,9% na Região Periférica do que na Região Central (41,7%. A presença de anemia também foi mais elevada em crianças cujos pais eram analfabetos. O risco de anemia foi superior entre as crianças que ingressaram no primeiro grau com idade superior a 8 anos. Não foi constatada presença significante de desnutrição aguda. Os resultados deste estudo destacam a anemia entre escolares como importante problema de Saúde Pública e ressaltam a urgência da implantação de programas de controle da anemia na população de escolares.

Anemia e desnutrição em escolares da rede pública do município de Osasco, São Paulo, Brasil

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Stefanini Maria Lúcia R.

1995-01-01

Full Text Available Com o objetivo de estimar a prevalência de anemia e conhecer o estado nutricional de escolares, foi realizado um estudo em uma amostra dos alunos ingressantes nas primeiras séries do primeiro grau das escolas públicas de Osasco, município integrante da Região Metropolitana de São Paulo. O diagnóstico de anemia foi feito através da dosagem da concentração de hemoglobina do sangue colhido por punção digital. O nível crítico utilizado para caracterizar a presença de anemia foi o estabelecido pela OMS. O estado nutricional foi avaliado utilizando os indicadores peso/idade e altura/idade expressos em escores Z e a população de referência do NCHS. A prevalência, de anemia encontrada foi de 51%n. Houve diferença nos níveis de prevalência quanto à localização geográfica das escolas, sendo maior (56,9% na Região Periférica do que na Região Central (41,7%. A presença de anemia também foi mais elevada em crianças cujos pais eram analfabetos. O risco de anemia foi superior entre as crianças que ingressaram no primeiro grau com idade superior a 8 anos. Não foi constatada presença significante de desnutrição aguda. Os resultados deste estudo destacam a anemia entre escolares como importante problema de Saúde Pública e ressaltam a urgência da implantação de programas de controle da anemia na população de escolares.

PREVALENCIA DE PARASITOSIS INTESTINAL Y ANEMIA EN NIÑOS BENEFICIARIOS DEL PROGRAMA VASO DE LECHE DE LA MUNICIPALIDAD DISTRITAL DE PATAPO –LAMBAYEQUE. 2017

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Jaramillo Llontop, Adela; Universidad Nacional Pedro Ruiz Gallo; Vergara Espinoza, Martha Arminda; Universidad Nacional Pedro Ruiz Gallo

2017-01-01

RESUMEN El objetivo del estudio fue determinar la prevalencia de parasitosis intestinal y anemia en niños de 1 a 6 años, beneficiarios del Programa de Vaso de leche de la Municipalidad Distrital de Patapo - anexo La Cría, departamento de Lambayeque 2017. Fueron seleccionados 60 niños  a quienes se les realizó un diagnóstico de parasitosis intestinal con la técnica coproparasitológica simple y el test de Graham y se les determinó anemia por el metodo de hematocrito. La prevalencia de parasitos...

CLASSIFICATION AND DIAGNOSTICS OF ANEMIA IN CHILDREN

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A. G. Rumyantsev

2011-01-01

Anemia in children is one of the most frequent somatic diseases. Criteria of anemia diagnosis are strictly regulated as decrease of hemoglobin/erythrocytes level accompanies majority of infectious, inflammatory, autoimmune, hereditary diseases and, in several cases, it is estimated as transitory disease in some periods of children’s growth and development. The article presents main classification and differential diagnostic schemes of anemia. Diagnostics makes accent on laboratory analysis; t...

An unusual cause of anemia and encephalopathy

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Sanjeev Kumar Sharma

2015-04-01

Full Text Available The authors present here an interesting case of recent onset anemia that was associated with an encephalopathy of the unusual cause.Although severe anemia can theoretically result in anemic hypoxia and can then lead to hypoxic encephalopathy, it is not a primary cause of encephalopathy. More frequently anemia can contribute together with other multiple causes of encephalopathy, such as infections, metabolic abnormalities, trauma, hepatic dysfunction, hypertension, toxins.

Anemia, tumor hypoxemia, and the cancer patient

International Nuclear Information System (INIS)

Varlotto, John; Stevenson, Mary Ann

2005-01-01

Purpose: To review the impact of anemia/tumor hypoxemia on the quality of life and survival in cancer patients, and to assess the problems associated with the correction of this difficulty. Methods: MEDLINE searches were performed to find relevant literature regarding anemia and/or tumor hypoxia in cancer patients. Articles were evaluated in order to assess the epidemiology, adverse patient effects, anemia correction guidelines, and mechanisms of hypoxia-induced cancer cell growth and/or therapeutic resistance. Past and current clinical studies of radiosensitization via tumor oxygenation/hypoxic cell sensitization were reviewed. All clinical studies using multi-variate analysis were analyzed to show whether or not anemia and/or tumor hypoxemia affected tumor control and patient survival. Articles dealing with the correction of anemia via transfusion and/or erythropoietin were reviewed in order to show the impact of the rectification on the quality of life and survival of cancer patients. Results: Approximately 40-64% of patients presenting for cancer therapy are anemic. The rate of anemia rises with the use of chemotherapy, radiotherapy, and hormonal therapy for prostate cancer. Anemia is associated with reductions both in quality of life and survival. Tumor hypoxemia has been hypothesized to lead to tumor growth and resistance to therapy because it leads to angiogenesis, genetic mutations, resistance to apoptosis, and a resistance to free radicals from chemotherapy and radiotherapy. Nineteen clinical studies of anemia and eight clinical studies of tumor hypoxemia were found that used multi-variate analysis to determine the effect of these conditions on the local control and/or survival of cancer patients. Despite differing definitions of anemia and hypoxemia, all studies have shown a correlation between low hemoglobin levels and/or higher amounts of tumor hypoxia with poorer prognosis. Radiosensitization through improvements in tumor oxygenation/hypoxic cell

[Effect of anemia on child development: long-term consequences].

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Zavaleta, Nelly; Astete-Robilliard, Laura

2017-01-01

Anemia in children younger than 3 years is a public health problem in Peru and worldwide. It is believed that one of the primary causes of anemia is iron deficiency. Numerous studies and reviews have reported that iron deficiency limited psychomotor development in children and that, despite the correction of anemia, children with iron deficiency experienced poorer long-term performance in cognitive, social, and emotional functioning. These outcomes were reported in observational studies, follow-up studies, and experimental studies with a control group. Anemia can decrease school performance, productivity in adult life, quality of life, and the general income of affected individuals. Here we describe possible mechanisms underlying the effect of iron deficiency, with or without anemia, on childhood development. The high rate of anemia in this age group is a cause for concern. Moreover, anemia should be prevented in the first year of life to avoid long-term negative effects on individual development.

Anemia em gestantes brasileiras antes e após a fortificação das farinhas com ferro

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Elizabeth Fujimori

2011-12-01

Full Text Available OBJETIVO: Comparar prevalência de anemia e valores de hemoglobina (Hb em gestantes brasileiras, antes e após a fortificação das farinhas com ferro. MÉTODOS: Estudo de avaliação de painéis repetidos, desenvolvido em serviços públicos de saúde de municípios das cinco regiões brasileiras. Dados retrospectivos foram obtidos de 12.119 prontuários de gestantes distribuídas em dois grupos: antes da fortificação, com parto anterior a junho de 2004, e após a fortificação, com última menstruação após junho de 2005. Anemia foi definida como Hb < 11,0 g/dL. Valores de Hb/idade gestacional foram avaliados segundo dois referenciais da literatura. Foram utilizados teste qui-quadrado, t de Student e regressão logística, com nível de 5% de significância. RESULTADOS: Na amostra total, anemia caiu de 25% para 20% após fortificação (p < 0,001, com médias de Hb significativamente maiores no grupo "após" (p < 0,001. Observaram-se, entretanto, diferenças regionais importantes: reduções significativas nas regiões Nordeste (37% para 29% e Norte (32% para 25%, onde as prevalências de anemia eram elevadas antes da fortificação, e reduções menores nas regiões Sudeste (18% para 15% e Sul (7% para 6%, onde as prevalências eram baixas. Os níveis de Hb/idade gestacional de ambos os grupos se mostraram discretamente mais elevados nos primeiros meses, porém bem mais baixos após o terceiro ou quarto mês, dependendo da referência utilizada para comparação. Análise de regressão logística mostrou que grupo, região geográfica, situação conjugal, trimestre gestacional, estado nutricional inicial e gestação anterior associaram-se com anemia (p < 0,05. CONCLUSÕES: A prevalência de anemia diminuiu após a fortificação, porém continua elevada nas regiões Nordeste e Norte. Embora a fortificação possa ter tido papel nesse resultado favorável, há que se considerar a contribuição de outras políticas p

Transient Ischemic Attack Caused by Iron Deficiency Anemia

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Ufuk Emre

2006-02-01

Full Text Available Transient Ischemic Attack Caused by Iron Deficiency Anemia Transient ischemic attacks are episodes of transient focal ischemia involving the brain or brainstem. They are commonly two to thirty minutes in duration and lasting less than 24 hours. Anemia of iron deficiency isn’t frequently cause for transient ischemic attack. It has been reported as a risk factor for childhood ischemic strokes. In the iron deficiency anemia, T‹A may develop as result of hypercoagulable state and increased viscosity that is caused by anemic hypoxia that is result of reduce hemoglobine level, seconder thrombosis and microcytose As iron deficiency anemia has been reported so rarely in adult patients with transient ischemic attacks as a cause, we aimed to discuss the clinical and outcome features of two cases with iron deficiency anemia and transient ischemic attacks in this study. Materials and methods: Routine neurologic examination, biochemical screen, serological tests, vasculitic markers, thyroid function tests, vitamin B 12 level, cranial imaging, vertebral carotid doppler USG examination was conducted in the two patients. Anemia of iron deficiency was found as the only risk factor for TIA and the two patients were treated with replacement of iron and antiagregan therapy. Neurological examination revealed no abnormality through the two years of follow-up. The iron deficiency anemia may be cause of many neurologic problems such a irritability, lethargy, headache, development retardation except from T‹A. In the iron deficiency anemia, early diagnosis and treatment is important

Thyroid storm and warm autoimmune hemolytic anemia.

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Moore, Joseph A; Gliga, Louise; Nagalla, Srikanth

2017-08-01

Graves' disease is often associated with other autoimmune disorders, including rare associations with autoimmune hemolytic anemia (AIHA). We describe a unique presentation of thyroid storm and warm AIHA diagnosed concurrently in a young female with hyperthyroidism. The patient presented with nausea, vomiting, diarrhea and altered mental status. Laboratory studies revealed hemoglobin 3.9g/dL, platelets 171×10 9 L -1 , haptoglobin storm and warm AIHA. She was started on glucocorticoids to treat both warm AIHA and thyroid storm, as well as antithyroid medications, propranolol and folic acid. Due to profound anemia and hemodynamic instability, the patient was transfused two units of uncrossmatched packed red blood cells slowly and tolerated this well. She was discharged on methimazole as well as a prolonged prednisone taper, and achieved complete resolution of the thyrotoxicosis and anemia at one month. Hyperthyroidism can affect all three blood cell lineages of the hematopoietic system. Anemia can be seen in 10-20% of patients with thyrotoxicosis. Several autoimmune processes can lead to anemia in Graves' disease, including pernicious anemia, celiac disease, and warm AIHA. This case illustrates a rarely described presentation of a patient with Graves' disease presenting with concurrent thyroid storm and warm AIHA. Copyright © 2017 Elsevier Ltd. All rights reserved.

Pyrexia due to megaloblastic anemia: An Unusual Case

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Singh PS, Vijay Verma, Vidyasagar, Granth Kumar

2014-07-01

Full Text Available Postmenopausal vegetarian female presented with short febrile illness associated with generalized weakness Clinical and investigative findings evidenced megaloblastic anemia Since none of investigations could pinpoint the cause for pyrexia and patient did not respond to empirical antibiotic and conservative antimalarial therapy, megaloblastic anemia itself was suspected to be cause for febrile episode Patient was treated with parenteral B12 and oral folic acid for megaloblastic anemia and she responded to it and became afebrile within 72 hours. Subsequently megaloblastic anemia was correlated to be cause of febrile illness.

Genetics Home Reference: X-linked sideroblastic anemia and ataxia

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... linked sideroblastic anemia and ataxia X-linked sideroblastic anemia and ataxia Printable PDF Open All Close All ... the expand/collapse boxes. Description X-linked sideroblastic anemia and ataxia is a rare condition characterized by ...

[Prevalence of anemia in reproductive-age Mexican women].

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Shamah-Levy, Teresa; Villalpando, Salvador; Mundo-Rosas, Verónica; De la Cruz-Góngora, Vanessa; Mejía-Rodríguez, Fabiola; Méndez Gómez-Humarán, Ignacio

2013-01-01

To update the prevalence of anemia and its trend in Mexican women of childbearing age over the past 13 years using information from the National Health and Nutrition Survey 2012 and 2006 (ENSANUT 2012 and ENSANUT 2006, respectively) and from the National Nutrition Survey 1999 (ENN 99). Data came from three national probabilistic surveys, representative at regional and rural / urban level. Hemoglobin (Hb) in women was measured using a HemoCue photometer and classified as anemia according to the WHO criteria. Frequencies and CI95% were estimated for each survey (ENSANUT 2012, ENSANUT 2006 and ENN 99) as well as percentage changes in anemia prevalence among pregnant and non-pregnant women in this survey sequence. The national prevalence of anemia in 2012 in non-pregnant women was 11.6% and in pregnant women was 17.9%. Between 1999 and 2012, a 10 percentage point (pp) decreasing in anemia prevalence was observed in the first ones and a 13.5 pp in the second ones. Although it has declined in the past 13 years, anemia in women of childbearing age remains as a serious public health problem. It is considered necessary to design strategies to prevent iron deficiency and for the early detection of anemia in women.

La didáctica del arte abstracto: realidad y juego en el aula de ELE

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Enrique Peláez Malagón

2012-08-01

Full Text Available Son por todos conocidas las deficiencias léxicas o gramaticales del alumno extranjero que viene a España a estudiar una segunda lengua. A estas deficiencias lingüísticas se unen en muchos casos las culturales, más concretamente la Historia del Arte, disciplina que aparece ofertada en muchos programas.

Reticulocyte parameters in hemoglobinopathies and iron deficiency anemia

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Cortellazzi Laura C.

2003-01-01

Full Text Available Flow cytometric reticulocyte analysis allows the evaluation of reticulocyte maturity. New reticulocyte parameters have been used in the diagnosis and management of anemias, in the bone marrow transplant setting and in the monitoring of iron replacement or erythropoiet in therapy. Reticulocyte numbers and maturation levels have been studied in different hemoglobinopathies and the results have been correlated with the degree of ineffective erythropoiesis. In order to verify differences in reticulocyte parameters in various types of anemias and to test the absolute number of immature reticulocytes as a possible discriminating factor among various types of anemias, reticulocyte counts were performed on 219 samples from patients with sickle cell anemia (SS (n= 62, hemoglobin S trait (n=9, Sbeta thalassemia (n=7, hemoglobin SC disease (n=11, beta thalassemia trait (n=33 and iron deficiency anemia (n= 47, and non-anemic individuals (n= 50. Mean fluorescence index (MFI was defined as representative of the degree of reticulocyte immaturity and it was evaluated as a percentage and in absolute values. Reticulocyte counts and MFI values were significantly higher in SS, Sbeta thalassemic and SC groups when compared to controls, but not different among the three anemia groups. Patients with hemoglobin S trait, iron deficiency anemia and beta thalassemia trait showed reticulocyte parameters similar to the non-anemic group. There was no difference between the b thalassemic trait and iron deficiency anemia in relation to any parameters. MFI in absolute numbers were significantly higher in anemias that develop with the hemolytic process, although this was not evident in MFI percentage values. Our results showed that the erythoid expansion in sickle cell diseases (SS, SC and Sb thalassemia leads to an enhanced immature reticulocyte release from bone marrow and that the phenomena is more evident by the MFI counting in absolute figures than in percentages. We

O significado da anemia falciforme no contexto da 'política racial' do governo brasileiro 1995-2004 The significance of sickle cell anemia within the context of the Brazilian government's 'racial policies' (1995-2004

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Peter H. Fry

2005-08-01

Full Text Available O objetivo deste ensaio é refletir sobre o significado social de um crescente interesse pela anemia falciforme e outras doenças associadas ao corpo negro no Brasil. Investigarei a rede discursiva que se formou em torno da doença no contexto social da sua produção. Começo resumindo a analise feita do antropólogo Melbourne Tapper, do programa de combate à Anemia Falciforme nos Estados Unidos nos anos 70, logo após as vitórias dos negros na luta pelos direitos civis. Tapper (1999 argumenta que uma das conseqüências dessa política foi a criação de uma comunidade negra cidadã e responsável. O Programa de Anemia Falciforme, desenvolvido pelo governo brasileiro com participação de ativistas negros a partir da década de 1990, também contribui para a formação e de uma "comunidade negra responsável". O argumento do artigo é que a anemia falciforme torna-se muito mais que uma doença a ser erradicada. O discurso em torno dela é um poderoso elemento no processo de naturalização da "raça negra" (e, por oposição lógica e política, da "raça branca" num país que se imaginava como biológica e culturalmente híbrido.This essay reflects on the social significance of growing interest in sickle cell anemia and other illnesses associated with the black body in Brazil. I explore the discursive network that has taken shape around the disease within the social context of its production. I first summarize anthropologist Melbourne Tapper's analysis of the United States program to fight sickle cell anemia in the 1970s, shortly after blacks attained victories in the civil rights movement. Tapper (1999 argues that one of the consequences of this policy was the creation of a responsible black citizenry. In the late 1990s, the Brazilian government developed a program (Programa de Anemia Falciforme that counted on the heavy participation of black activists and that also contributed to the formation of a "responsible black community. My

Impacto de orientação dietética sistemática no primeiro ano de vida nas prevalências de anemia e deficiência de ferro aos 12-16 meses

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Gisele Ane Bortolini

2012-02-01

Full Text Available OBJETIVO: Avaliar o impacto de uma intervenção baseada em orientação dietética na prevalência de deficiência de ferro, anemia e anemia por deficiência de ferro entre crianças na idade de 12 a 16 meses. MÉTODOS: Recém-nascidos foram randomizados para compor os grupos intervenção e controle. As mães do grupo intervenção receberam orientações dietéticas durante 10 visitas domiciliares realizadas nos primeiros 10 dias após o parto, mensalmente até os 6 meses e, posteriormente, aos 8, 10 e 12 meses; o grupo controle recebeu apenas visitas para coletas de dados nas idades de 6 e 12 meses. Quando as crianças apresentaram idade de 12 a 16 meses, realizou-se inquérito alimentar recordatório de 24 horas, hemograma e ferritina. RESULTADOS: Os resultados mostraram que não houve evidência de efeito da intervenção sobre a ocorrência de anemia, a qual foi de 66,5% no grupo intervenção e de 61,8% no grupo controle. Também não houve diferença na prevalência de deficiência de ferro e anemia por deficiência de ferro entre os grupos. No entanto, foi evidenciado melhor padrão alimentar nas crianças do grupo intervenção. Maior proporção de crianças do grupo intervenção foi amamentada exclusivamente na idade de 4 a 6 meses e amamentada nas idades de 6 a 12 meses. Além de apresentar maior consumo de carne e dietas com maior biodisponibilidade em ferro, também apresentaram menor consumo de leite de vaca e cálcio do que as crianças do grupo controle. CONCLUSÃO: A intervenção não resultou em redução na prevalência de anemia, deficiência de ferro e anemia por deficiência de ferro. Número de identificação de registro de ensaios clínicos: NCT00629629.

Prevalence, severity, and related factors of anemia in HIV/AIDS patients

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Mohsen Meidani

2012-01-01

Full Text Available Objective: The prevalence of anemia in HIV infected patients has not been well characterized in Iran. This study aimed to describe the prevalence of anemia and related factors in HIV positive patients. Materials and Methods: In a cross-sectional study, anemia prevalence and risk factors of 212 HIV positive patients were assessed, at the behavioral disease consulting center in Isfahan. The relationship between anemia, demographic variables, and clinical histories were analyzed. Mild to moderate anemia was defined as hemoglobin 8-13 g/dL for men and 8-12 g/dL for women. Severe anemia was defined as hemoglobin, 8 g/dL. Results: A total of 212 HIV positive patients with a mean±SD age of 36.1 ± 9.1 years were assessed. We found that hemoglobin levels were between 4.7 and 16.5 gr/dL. In this study, the overall prevalence of anemia was 71%, with the majority of patients having mild to moderate anemia. Mild to moderate anemia and severe anemia occurred in 67% and 4% of patients, respectively. The mean absolute CD4 count was 348 ± 267.8 cells/cubic mm. Sixty one of 212 patients were at late stage of HIV infection (males=51 and female=10. Of the 212 HIV positive patients enrolled, 17 (8% had a positive history of tuberculosis. We found a strong association between anemia and death. Conclusion: Normocytic anemia with decreased reticulocyte count was the most common type of anemia in overall. Prevalence of anemia in this study is relatively higher than other similar studies. Such a high prevalence of anemia needs close monitoring of patients on a zidovudine-based regimen. Better screening for anemia and infectious diseases, and modified harm reduction strategy (HRS for injection drug users are primary needs in HIV seropositive patients.

Adesão à antibioticoterapia profilática em crianças com anemia falciforme: um estudo prospectivo Compliance with antibiotic prophylaxis in children with sickle cell anemia: a prospective study

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Enio Latini Bitarães

2008-08-01

Full Text Available OBJETIVO: Avaliar a adesão a antibiótico profilático em crianças com anemia falciforme. MÉTODOS: Estudo prospectivo de 108 crianças (idade entre 3 meses e 4,5 anos, 45% masculino seguidas por 15 meses no Hemocentro de Belo Horizonte. Avaliou-se a adesão por meio de três entrevistas com cuidadores, análise de prontuário médico e atividade antibacteriana em uma amostra de urina em 81 crianças. Os antibióticos foram dispensados gratuitamente. RESULTADOS: Penicilina foi usada em 106 casos (maioria via oral, e eritromicina, dois casos. O antibiótico foi detectado na urina de 56% das crianças; 48% dos cuidadores afirmaram nas entrevistas que nenhuma dose deixou de ser administrada; em 89% dos prontuários médicos, não se registrou falha de adesão. Considerando-se aderente a criança que não apresentasse falhas em nenhum ou em apenas um dos métodos, a taxa de adesão foi de 67%. O grau de concordância entre os três métodos para medir a adesão foi baixo. Não se demonstrou qualquer associação entre a taxa de adesão e o gênero, estado nutricional, renda familiar per capita, nível educacional dos cuidadores ou número de membros da família. CONCLUSÕES: A taxa de adesão à antibioticoterapia profilática foi baixa quando avaliada por meio de questionários e testes urinários, e superestimada quando avaliada pela consulta ao prontuário médico. A adesão deve ser preferencialmente avaliada por vários métodos, pois sua mensuração é complexa. Os resultados do presente estudo sugerem a necessidade de programas educacionais abrangentes para os profissionais de saúde, para as famílias e crianças portadoras de anemia falciforme.OBJECTIVE: To prospectively assess compliance with antibiotic prophylaxis among children with sickle cell anemia. METHODS: A total of 108 children (aged 3 months to 4½ years, 45% male were recruited from the Hematology Center in Belo Horizonte, Brazil, and followed up for 15 months. Data on

Variación en la producción de alcaloides en inflorescencias de Senecio Grisebachii por deficiencia de nutrientes Alkaloid production changes due to nutrient deficiencies in Senecio Grisebachii inflorescences

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Margarita A Yaber Grass

2009-06-01

Full Text Available Senecio grisebachii Baker es una maleza que invade pasturas naturales y cultivos en el sur de Brasil, Uruguay, y provincias mesopotámicas y Buenos Aires en la Argentina y es considerada tóxica debido a la presencia de alcaloides pirrolizidínicos (APs en sus tejidos. Se evaluó el efecto de la deficiencia de nitrógeno y de fósforo sobre el perfil de APs en inflorescencias de esta maleza. Se realizó un ensayo utilizando un diseño completamente aleatorizado con 10 repeticiones, en el cual las plantas, que crecieron en hidroponia desde mayo hasta octubre, fueron regadas con solución de nutrientes en las que las concentraciones de N o de P reducidas en un 50% respecto del control. La cuantificación de APs en las inflorescencias de S. grisebachii por CG y CG-EM, demuestra un aumento significativo en el contenido total de APs, en los tratamientos con déficit en N o P (1,33 y 1,34 mg g-1 de materia seca, respectivamente, comparados con el control 0,35 mg g-1. Se identificaron siete APs y sus concentraciones variaron entre tratamientos. Senecionina resultó el alcaloide mayoritario en el tratamiento déficit de N, mientras senecifilina resultó más abundante en los tratamientos control y con déficit de P, seguidos en todos los casos por integerrimina y cantidades menores de espartiodina, jacobina, jacozina y retrorsina.Senecio grisebachii Baker is a weed that invades natural pastures and crops in southern Brazil, Uruguay, the mesopotamic provinces and Buenos Aires in Argentina, and is considered to be toxic because of the presence of pyrrolizidine alkaloids (PAs in its tissues. The effects of nitrogen and phosphorus deficiency was evaluated on the APs patterns of the weed inflorescences. A completely randomized design with 10 repetitions was used in an experiment where plants growing in hydroponics from May to October were irrigated with a nutrient solution containing 50% P or N concentrations with respect to the control treatment. PAs

Iron Deficiency and Anemia Predict Mortality in Patients with Tuberculosis123

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Isanaka, Sheila; Mugusi, Ferdinand; Urassa, Willy; Willett, Walter C.; Bosch, Ronald J.; Villamor, Eduardo; Spiegelman, Donna; Duggan, Christopher; Fawzi, Wafaie W.

2012-01-01

Many studies have documented a high prevalence of anemia among tuberculosis (TB) patients and anemia at TB diagnosis has been associated with an increased risk of death. However, little is known about the factors contributing to the development of TB-associated anemia and their importance in TB disease progression. Data from a randomized clinical trial of micronutrient supplementation in patients with pulmonary TB in Tanzania were analyzed. Repeated measures of anemia with iron deficiency, anemia without iron deficiency, and iron deficiency without anemia were assessed as risk factors for treatment failure, TB recurrence, and mortality. The prevalence of anemia (hemoglobin iron deficiency (mean corpuscular volume , 80 fL). We found no evidence of an association between anemia (with or without iron deficiency) or iron deficiency without anemia at baseline and the risk of treatment failure at 1 mo after initiation. Anemia without iron deficiency was associated with an independent, 4-fold increased risk of TB recurrence [adjusted RR = 4.10 (95% CI = 1.88, 8.91); P Iron deficiency and anemia (with and without iron deficiency) were associated with a 2- to nearly 3-fold independent increase in the risk of death [adjusted RR for iron deficiency without anemia = 2.89 (95% CI = 1.53, 5.47); P = 0.001; anemia without iron deficiency = 2.72 (95% CI = 1.50, 4.93); P = 0.001; iron deficiency anemia = 2.13 (95% CI = 1.10, 4.11); P = 0.02]. Efforts to identify and address the conditions contributing to TB-associated anemia, including iron deficiency, could play an important role in reducing morbidity and mortality in areas heavily affected by TB. PMID:22190024

Salmonella osteomyelitis by sickle cell anemia

International Nuclear Information System (INIS)

Rausch, H.; Tran, V.T.; Boeckmann, U.; Duesseldorf Univ.

1985-01-01

Case report of a 28 year old black sickle cell anemia patient with salmonella osteomyelitis of the radius. Aside from sickle cell anemia patients this skeletal complication of enteric salmonellosis is an extreme rarity. Description of the typical roentgenological features includes intracortical fissures and sequestration. (orig.) [de

Fanconi anemia (cross)linked to DNA repair.

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Niedernhofer, Laura J; Lalai, Astrid S; Hoeijmakers, Jan H J

2005-12-29

Fanconi anemia is characterized by hypersensitivity to DNA interstrand crosslinks (ICLs) and susceptibility to tumor formation. Despite the identification of numerous Fanconi anemia (FANC) genes, the mechanism by which proteins encoded by these genes protect a cell from DNA interstrand crosslinks remains unclear. The recent discovery of two DNA helicases that, when defective, cause Fanconi anemia tips the balance in favor of the direct involvement of the FANC proteins in DNA repair and the bypass of DNA lesions.

Anemia and iron deficiency before and after bariatric surgery.

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Salgado, Wilson; Modotti, Caue; Nonino, Carla Barbosa; Ceneviva, Reginaldo

2014-01-01

Iron deficiency and anemia are changes often associated with obesity. Bariatric surgery is responsible for increasing the iron loss and reducing its absorption. The objective of this study was to evaluate anemia and iron deficiency before and after bariatric surgery and to relate them to possible predisposing factors. A retrospective study was conducted on obese patients submitted to open Roux-en-Y gastric bypass, in which clinical and laboratory data were obtained up to 48 months postoperatively. Patients were divided into groups according to the presence or absence of anemia and to the presence or absence of iron deficiency (even without anemia), and all data were compared between these groups. Preoperatively, 21.5% of patients had anemia and 20% had iron deficiency. The number of patients with anemia did not vary through the 4 years of the study, but ferritin levels significantly decreased with time (Panemia. Female gender was a variable associated with a greater incidence of iron deficiency. Anemia and iron deficiency are frequent in obese patients and must be treated before surgery. Medical and nutritional surveillance is important in the postoperative period of bariatric surgery. Management of each condition must be directed at correcting the 2 major sources of iron deficiency and anemia: food intolerance (mostly meat intolerance) and losses (frequently due to menstruation). These are the factors more related to iron deficient anemia. Copyright © 2014 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

Iron deficiency, anemia, and mortality in renal transplant recipients.

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Eisenga, Michele F; Minović, Isidor; Berger, Stefan P; Kootstra-Ros, Jenny E; van den Berg, Else; Riphagen, Ineke J; Navis, Gerjan; van der Meer, Peter; Bakker, Stephan J L; Gaillard, Carlo A J M

2016-11-01

Anemia, iron deficiency anemia (IDA), and iron deficiency (ID) are highly prevalent in renal transplant recipients (RTR). Anemia is associated with poor outcome, but the role of ID is unknown. Therefore, we aimed to investigate the association of ID, irrespective of anemia, with all-cause mortality in RTR. Cox regression analyses were used to investigate prospective associations. In 700 RTR, prevalences of anemia, IDA, and ID were 34%, 13%, and 30%, respectively. During follow-up for 3.1 (2.7-3.9) years, 81 (12%) RTR died. In univariable analysis, anemia [HR, 1.72 (95%CI: 1.11-2.66), P = 0.02], IDA [2.44 (1.48-4.01), P anemia with mortality became weaker after adjustment for ID [1.52 (0.97-2.39), P = 0.07] and disappeared after adjustment for proteinuria and eGFR [1.09 (0.67-1.78), P = 0.73]. The association of IDA with mortality attenuated after adjustment for potential confounders. In contrast, the association of ID with mortality remained independent of potential confounders, including anemia [1.77 (1.13-2.78), P = 0.01]. In conclusion, ID is highly prevalent among RTR and is associated with an increased risk of mortality, independent of anemia. As ID is a modifiable factor, correction of ID could be a target to improve survival. © 2016 The Authors. Transplant International published by John Wiley & Sons Ltd on behalf of Steunstichting ESOT.

[Spatial analysis of gestational anemia in Peru, 2015].

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Hernández-Vásquez, Akram; Azañedo, Diego; Antiporta, Daniel A; Cortés, Sandra

2017-01-01

To establish regional prevalences of anemia in pregnant women receiving care at public clinics in Peru in 2015 and identify high-prevalence district conglomerates. An ecological study was carried out on data from pregnant women with anemia registered on the Nutritional Status Information System (SIEN) who received care in 7703 public clinics in 2015. Regional and district prevalences of gestational anemia were calculated. District conglomerates with a high prevalence of gestational anemia were identified using the Moran Index. Information was gathered from 311,521 pregnant women distributed in 1638 districts in Peru. The national prevalence of anemia was 24.2% (95% confidence interval [95% CI]: 24.0-24.3%), the rural prevalence was 30.5%, and the urban prevalence was 22.0%. The regions of Huancavelica (45.5%; 95% CI: 44.2-46.7%), Puno (42.8%; 95% CI: 41.9-43.7%), Pasco (38.5%; 95% CI: 36.9-40.0%), Cusco (36.0%; 95% CI: 35.3-36.8%), and Apurímac (32.0%; 95% CI: 30.8-33.1%) had the highest prevalences of anemia. The local Moran Index identified 202 high-priority districts (hot spots) (12.3% of total; 44 urban and 158 rural) located in Ancash, Apurímac, Arequipa, Ayacucho, Cajamarca, Cusco, Huancavelica, Huánuco, Junín, La Libertad, Lima, Pasco, and Puno containing high-prevalence district conglomerates. Gestational anemia in Peru has its highest prevalence rates in rural and southern mountainous areas. The district conglomerates with high prevalence rates of gestational anemia coincide with the areas of high regional prevalence.

Severe anemia in 3 toddlers with gastric lactobezoar.

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Klein-Franke, A; Kropshofer, G; Gassner, I; Meister, B; Salvador, C; Scholl-Bürgi, S; Mueller, T; Heinz-Erian, P

2013-05-01

Anemia in toddlers may result from many disorders including excessive feeding with cow's milk. Another sequel of age-inadequate cow's milk nutrition may be gastric lactobezoar (GLB), a dense lump of coagulated milk and mucus in the stomach. 3 toddlers presented with a history of excessive intake of full cream cow's milk, abdominal distension, vomiting, dehydration, fatigue, marked pallor and tachycardia. Diagnostic imaging revea-led large GLBs as the likely origin of the abdominal symptoms. Laboratory evaluation showed severe anemia with depleted iron stores and signs of protein catabolism. Non-cow's milk-induced causes of anemia including defects of erythropoiesis, hemoglobin structure, RBC-enzymes and blood coagulation, hemolysis, immune disorders, infection, inflammation, extraintestinal hemorrhage, nephropathy were - according to the available data - unlikely to cause the anemia in our patients. Thus their anemia is thought to be due to age-inadequate cow's milk nutrition leading to 1) low intake, decreased absorption/bioavailability and increased intestinal loss of iron, and 2) GLB which induced blood loss following mechanical irritation of the gastric mucosa and vomiting causing high gastric pH and decrease in duodenal iron absorption. The anemia in our patients is due to both exaggerated feeding with cow's milk and adverse effects of GLBs. This hypothesis is supported by the finding that, after erythrocyte transfusion, iron substitution, age-adapted nutrition and GLB-dissolution, the anemia did not recur. We propose to include GLB in the differential diagnosis of anemia in cow's milk fed small children. © Georg Thieme Verlag KG Stuttgart · New York.

An Etiologic Profile of Anemia in 405 Geriatric Patients

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Tabea Geisel

2014-01-01

Full Text Available Background. Anemia is a common condition in the elderly and a significant risk factor for increased morbidity and mortality, reducing not only functional capacity and mobility but also quality of life. Currently, few data are available regarding anemia in hospitalized geriatric patients. Our retrospective study investigated epidemiology and causes of anemia in 405 hospitalized geriatric patients. Methods. Data analysis was performed using laboratory parameters determined during routine hospital admission procedures (hemoglobin, ferritin, transferrin saturation, C-reactive protein, vitamin B12, folic acid, and creatinine in addition to medical history and demographics. Results. Anemia affected approximately two-thirds of subjects. Of 386 patients with recorded hemoglobin values, 66.3% were anemic according to WHO criteria, mostly (85.1% in a mild form. Anemia was primarily due to iron deficiency (65%, frequently due to underlying chronic infection (62.1%, or of mixed etiology involving a combination of chronic disease and iron deficiency, with absolute iron deficiency playing a comparatively minor role. Conclusion. Greater awareness of anemia in the elderly is warranted due to its high prevalence and negative effect on outcomes, hospitalization duration, and mortality. Geriatric patients should be routinely screened for anemia and etiological causes of anemia individually assessed to allow timely initiation of appropriate therapy.

Refractory iron-deficiency anemia and gluten intolerance: Response to gluten-free diet Anemia ferropénica refractaria e intolerancia al gluten: respuesta a la dieta sin gluten

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Luis Rodrigo-Sáez

2011-07-01

: determinar la prevalencia de marcadores serológicos, genéticos e histológicos de intolerancia al gluten y analizar la respuesta a la retirada del gluten de la dieta en estos pacientes. Métodos: se incluyeron de forma prospectiva y consecutiva una serie de pacientes con anemia refractaria. Se les aplicó un protocolo consistente en determinación marcadores serológicos (TGt-2, genéticos (HLA-DQ2/DQ8 e histológicos de enfermedad celíaca. Todos siguieron una dieta sin gluten durante una mediana de 3,6 años. Se interpretó como respuesta positiva la desaparición mantenida de la anemia durante el seguimiento. Resultados: se estudiaron 98 pacientes (84% mujeres con una edad media de 54 años. Los ac. anti-TGt2 fueron positivos en el 5% de los casos. Un total de 67 casos (68% presentaban el haplotipo HLA-DQ2 o DQ8 (+. Encontramos atrofia vellositaria (Marsh III en el 13% de los casos y patrón inflamatorio (Marsh I o II en el 13%. Los 72 casos restantes (74% no presentaban alteraciones histológicas duodenales. Se compararon la edad, el tiempo de evolución de la anemia, número de transfusiones, número de dosis de hierro parenteral y tiempo en dieta sin gluten, en función de la presencia o no de atrofia vellositaria y de la positividad para el HLA-DQ2/8, sin encontrar diferencias significativas en ninguna de las variables analizadas. La respuesta fue positiva en el 92% de los casos. Conclusiones: la enfermedad celiaca con atrofia vellositaria es causa poco frecuente de anemia refractaria. Las formas de intolerancia al gluten sin lesión histológica asociada, representan cerca del 75% de los casos y desempeñan, por lo tanto, un papel importante en su aparición.

Deficiencia de 25-hidoroxivitamina D, VDBP y péptidos antimicrobianos vitamina D dependientes en el paciente séptico

OpenAIRE

Pérez San Martín, Sonia

2017-01-01

Introducción: La vitamina D desempeña un papel importante en la regulación de la inflamación y protección frente a las infecciones, induciendo la síntesis de péptidos antimicrobianos. La deficiencia de vitamina D se ha asociado con un incremento de mortalidad en pacientes sépticos adultos. La proteína transportadora de vitamina D (VDBP) también tiene funciones antiinflamatorias y autoinmunes. Objetivo: Evaluar los niveles de 25-hidroxivitamina D (25(OH) D), 1,25-dihidroxi vitamina D (1,25(OH)...

Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages.

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Garbati, Michael R; Hays, Laura E; Rathbun, R Keaney; Jillette, Nathaniel; Chin, Kathy; Al-Dhalimy, Muhsen; Agarwal, Anupriya; Newell, Amy E Hanlon; Olson, Susan B; Bagby, Grover C

2016-03-01

The Fanconi anemia proteins participate in a canonical pathway that repairs cross-linking agent-induced DNA damage. Cells with inactivated Fanconi anemia genes are universally hypersensitive to such agents. Fanconi anemia-deficient hematopoietic stem cells are also hypersensitive to inflammatory cytokines, and, as importantly, Fanconi anemia macrophages overproduce such cytokines in response to TLR4 and TLR7/8 agonists. We questioned whether TLR-induced DNA damage is the primary cause of aberrantly regulated cytokine production in Fanconi anemia macrophages by quantifying TLR agonist-induced TNF-α production, DNA strand breaks, crosslinker-induced chromosomal breakage, and Fanconi anemia core complex function in Fanconi anemia complementation group C-deficient human and murine macrophages. Although both M1 and M2 polarized Fanconi anemia cells were predictably hypersensitive to mitomycin C, only M1 macrophages overproduced TNF-α in response to TLR-activating signals. DNA damaging agents alone did not induce TNF-α production in the absence of TLR agonists in wild-type or Fanconi anemia macrophages, and mitomycin C did not enhance TLR responses in either normal or Fanconi anemia cells. TLR4 and TLR7/8 activation induced cytokine overproduction in Fanconi anemia macrophages. Also, although TLR4 activation was associated with induced double strand breaks, TLR7/8 activation was not. That DNA strand breaks and chromosome breaks are neither necessary nor sufficient to account for the overproduction of inflammatory cytokines by Fanconi anemia cells suggests that noncanonical anti-inflammatory functions of Fanconi anemia complementation group C contribute to the aberrant macrophage phenotype and suggests that suppression of macrophage/TLR hyperreactivity might prevent cytokine-induced stem cell attrition in Fanconi anemia. © Society for Leukocyte Biology.

[Anemia: guidelines comparison].

Science.gov (United States)

Del Vecchio, Lucia

2009-01-01

The development of recombinant human erythropoietin and its introduction into the market in the late 1980s has significantly improved the quality of life of patients with chronic kidney disease (CKD) and reduced the need for blood transfusions. Starting from a cautious target, a progressive increase in the recommended hemoglobin levels has been observed over the years, in parallel with an increase in the obtained levels. This trend has gone together with the publication of findings of observational studies showing a relationship between the increase in hemoglobin levels and a reduction in the mortality risk, with the conduction of clinical trials testing the effects of complete anemia correction, and with the compilation of guidelines on anemia control in CKD patients by scientific societies and organizations. In the last two years, evidence of a possible increase in the mortality risk in those patients who were randomized to high hemoglobin levels has resulted in a decrease in the upper limit of the recommended Hb target to be obtained with erythropoietin stimulating agents (ESA), and consequently in a narrowing of the target range. Comparison of guidelines on anemia control in CKD patients is an interesting starting point to discuss single recommendations, strengthen their importance, or suggest new topics of research to fill up important gaps in knowledge.

Frequency of anemia in chronic psychiatry patients

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Korkmaz S

2015-10-01

Full Text Available Sevda Korkmaz,1 Sevler Yildiz,1 Tuba Korucu,1 Burcu Gundogan,1 Zehra Emine Sunbul,1 Hasan Korkmaz,2 Murad Atmaca1 1Department of Psychiatry, 2Department of Cardiology, Faculty of Medicine, Firat University, Elazig, Turkey Purpose: Anemia could cause psychiatric symptoms such as cognitive function disorders and depression or could deteriorate an existing psychiatric condition when it is untreated. The objective of this study is to scrutinize the frequency of anemia in chronic psychiatric patients and the clinical and sociodemographic factors that could affect this frequency.Methods: All inpatients in our clinic who satisfied the study criteria and received treatment between April 2014 and April 2015 were included in this cross-sectional study. Sociodemographic data for 378 patients included in the study and hemoglobin (Hb and hematocrit values observed during their admission to the hospital were recorded in the forms. Male patients with an Hb level of <13 g/dL and nonpregnant female patients with an Hb level of <12 g/dL were considered as anemic.Findings: Axis 1 diagnoses demonstrated that 172 patients had depressive disorder, 51 patients had bipolar disorder, 54 patients had psychotic disorder, 33 patients had conversion disorder, 19 patients had obsessive-compulsive disorder, 25 patients had generalized anxiety disorder, and 24 patients had other psychiatric conditions. It was also determined that 25.4% of the patients suffered from anemia. Thirty-five percent of females and 10% of males were considered as anemic. The frequency of anemia was the highest among psychotic disorder patients (35%, followed by generalized anxiety disorder patients (32%, and obsessive-compulsive disorder patients (26%. Anemia was diagnosed in 22% of depressive disorder patients, 25% of bipolar disorder patients, and 24% of conversion disorder patients.Results: The prevalence of anemia among chronic psychiatry patients is more frequent than the general population

Oral human papillomavirus is common in individuals with Fanconi anemia.

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Sauter, Sharon L; Wells, Susanne I; Zhang, Xue; Hoskins, Elizabeth E; Davies, Stella M; Myers, Kasiani C; Mueller, Robin; Panicker, Gitika; Unger, Elizabeth R; Sivaprasad, Umasundari; Brown, Darron R; Mehta, Parinda A; Butsch Kovacic, Melinda

2015-05-01

Fanconi anemia is a rare genetic disorder resulting in a loss of function of the Fanconi anemia-related DNA repair pathway. Individuals with Fanconi anemia are predisposed to some cancers, including oropharyngeal and gynecologic cancers, with known associations with human papillomavirus (HPV) in the general population. As individuals with Fanconi anemia respond poorly to chemotherapy and radiation, prevention of cancer is critical. To determine whether individuals with Fanconi anemia are particularly susceptible to oral HPV infection, we analyzed survey-based risk factor data and tested DNA isolated from oral rinses from 126 individuals with Fanconi anemia and 162 unaffected first-degree family members for 37 HPV types. Fourteen individuals (11.1%) with Fanconi anemia tested positive, significantly more (P = 0.003) than family members (2.5%). While HPV prevalence was even higher for sexually active individuals with Fanconi anemia (17.7% vs. 2.4% in family; P = 0.003), HPV positivity also tended to be higher in the sexually inactive (8.7% in Fanconi anemia vs. 2.9% in siblings). Indeed, having Fanconi anemia increased HPV positivity 4.9-fold (95% CI, 1.6-15.4) considering age and sexual experience, but did not differ by other potential risk factors. Our studies suggest that oral HPV is more common in individuals with Fanconi anemia. It will be essential to continue to explore associations between risk factors and immune dysfunction on HPV incidence and persistence over time. HPV vaccination should be emphasized in those with Fanconi anemia as a first step to prevent oropharyngeal cancers, although additional studies are needed to determine whether the level of protection it offers in this population is adequate. ©2015 American Association for Cancer Research.

The Student with Sickle Cell Anemia.

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Tetrault, Sylvia M.

1981-01-01

Sickle cell anemia is the most common and severe of inherited chronic blood disorders. In the United States, sickle cell anemia is most common among the Black population. Among the most commonly occurring symptoms are: an enlarged spleen, episodes of severe pain, easily contracted infections, skin ulcers, and frequent urination. (JN)

A novel ubiquitin ligase is deficient in Fanconi anemia.

NARCIS (Netherlands)

Meetei, AR; Winter, de J.P.; Medhurst, A.L. dr.; Wallisch, M; Waisfisz, Q.; Vrugt, van der H.J.; Oostra, A.B.; Yan, Z; Ling, C; Bishop, CE; Hoatlin, M.E.; Joenje, H.

2003-01-01

Fanconi anemia is a recessively inherited disease characterized by congenital defects, bone marrow failure and cancer susceptibility. Cells from individuals with Fanconi anemia are highly sensitive to DNA-crosslinking drugs, such as mitomycin C (MMC). Fanconi anemia proteins function in a DNA damage

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... for gastrointestinal bleeding To see if gastrointestinal bleeding is causing your iron-deficiency anemia, your doctor may order the following procedures to guide treatment . Fecal ...

Sickle Cell Anemia: MedlinePlus Health Topic

Science.gov (United States)

... Cell Disease Also called: Hemoglobin SS disease, Sickle cell anemia On this page Basics Summary Start Here Diagnosis ... red blood cells. This is a condition called anemia , and it can make you feel tired. The ...

Análisis de las evaluaciones efectuadas a las intervenciones médico-humanitarias ejecutadas por médicos sin fronteras, en respuesta a epidemias, desastrees y enfermedades olvidades, en el período 2005-2010

OpenAIRE

Rubens, Daniel

2015-01-01

Las evaluaciones a los proyectos de asistencia humanitaria constituyen un apartado especial en el contexto del ejercicio evaluativo, relevantes dado el carácter social y político de los proyectos de intervención humanitaria, que responden a las necesidades de poblaciones extremadamente vulnerables y marginalizadas. Esta investigación de tipo metaevaluación sobre informes de evaluación de proyectos humanitarios realizados por MSF-OCBA revela una deficiencia en términos de presencia y precisión...

Ocular lesions and experimental choline deficiency Lesiones oculares y deficiencia experimental de colina

Directory of Open Access Journals (Sweden)

Georgina P. Ossani

2006-10-01

Full Text Available Previous studies have shown ocular haemorrhages in choline-deficient rats. The aim of this paper is to study further the relationship between ocular and renal lesions and biochemical alterations in rats fed a choline-deficient diet. Fifty one weanling male Wistar rats, were divided into two groups. Thirty one of them were fed a choline-deficient diet and the rest was fed a choline-supplemented diet ad libitum. Animals from both groups were killed between the fifth and the eighth day. Urea, creatinine and homocysteine concentrations in blood were determined. Eyes were used for light microscopy study; high resolution light microscopy and the study of the retina as "rétine a plat". Kidneys were studied by light microscopy. Choline-supplemented rats did not show ocular or renal lesion. Choline-deficient rats that showed renal lesions, tubular or cortical necrosis, did not always have ocular changes. There were no ocular changes in the only choline-deficient rat without renal lesion. The ocular changes consisted mainly in haemorrhage in both cameras and ciliary and vitreous bodies. Correlations between ocular and renal lesion (r=0.72, pEstudios previos han demostrado hemorragia ocular en ratas deficientes en colina. El objetivo de este trabajo es profundizar en la relación entre las alteraciones oculares, renales y bioquímicas en ratas deficientes en colina. Cincuenta y una ratas Wistar macho recién destetadas fueron divididas en dos grupos: treinta y una fueron alimentadas con una dieta colino deficiente y el resto con colina suplementada ad-libitum. Los animales de ambos grupos fueron sacrificados entre el quinto y el octavo día. Se midió la concentración de urea, creatinina y homocisteína en sangre. Los ojos fueron estudiados por microscopía de luz, microscopía óptica de alta resolución y para el estudio de la retina como retina plana. Los riñones fueron estudiados por microscopía de luz. Las ratas suplementadas con colina no

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... Supplement Fact Sheet (NIH) Iron-Deficiency Anemia (National Library of Medicine, MedlinePlus) ... Privacy Policy Freedom of Information Act (FOIA) Accessibility Copyright and Usage No FEAR ...

Epidemiology of aplastic anemia in Japanese radiological technicians

International Nuclear Information System (INIS)

Kitabatake, Takashi; Watanabe, Tsuyoshi; Saito, Akira; Nakamura, Minoru.

1976-01-01

Among Japanese radiological technicians, four deaths from aplastic anemia have been recorded. Based on this fact, some epidemiological considerations are tried. During the period from 1930 to 1960, the population of radiological technicians is estimated to be 74,400 man-years, in which 0.5 aplastic anemias are expected. However actually three died from aplastic anemia. This difference is statistically significant at the 1% level. On the other hand, in the period from 1961 to 1973, the observed value is 1 against 0.7 expected. It is concluded that aplastic anemia had been frequently induced among Japanese radiological technicians in the era when there was much exposure to occupational radiation. (auth.)

Aplastic anemia and related disorders in atomic bomb survivors

International Nuclear Information System (INIS)

Ichimaru, Michito; Tomonaga, Yu; Matsunaga, Masako; Sadamori, Naoki; Ishimaru, Toranosuke.

1978-01-01

Whether the incidence of aplastic anemia significantly increases due to the later effect of atomic-bomb radiation was studied. After the data of aplastic anemia which occurred within 1950 - 1973 were evaluated and the diagnoses of the cases were certified, the incidence of aplastic anemia per 109,000 inhabitants of the cities of Hiroshima and Nagasaki was calculated and compared according to the dose of atomic-bomb radiation. There was no increase in the incidence according to an increase in radiation dose, and there was no fact that aplastic anemia increased in a certain period either. Most of the atomic-bomb survivors who were close to the epicenter and were clinically diagnosed as aplastic anemia had leukemia lesion or myeloid proliferating lesion, and it is likely to be that pathological changes resembling aplastic anemia may appear in a certain phase of myeloid proliferation or as a phenotype of myeloid proliferation. An evaluation was made on cases of aplastic anemia of other groups, but the doses of atomic-bomb radiation which they received were not so much to give effect on the bone marrow except only two cases. (Ueda, J.)

FAKTOR-FAKTOR YANG MEMPENGARUHI ANEMIA PADA REMAJA

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Dewi Permaesih

2012-09-01

Full Text Available Anemia in Indonesia is a public health problem. The prevalence still have a tendency to increase. The main antecedent factor for anemia is the lack of iron intake. The purpose of this analysis is to learn and find other factors besides iron. Sources of data were from the study of morbidity and disability of the Household Health Survey, 2001. The respondents were adolescents between 10-19 years of age. Data on social economic status, illness records, medicine consumption, physical activities and smoking habits were collected by interview during household visits. Data on anemia were identified from the results of hemoglobin determination by HemoCue. The nutrition status was found from the calculation of Body Mass Index. Data on energy consumption were taken from food expenditure for meal data from SUSENAS. Variable used for the purpose of this analysis were age, gender, smoking habit, alcohol drinking, breakfast, the use of time for physical activities, IMT, hemoglobin value and energy consumption. Data analyse were conducted in 3 stages,i.e., univariate, bivariate and multivariate analyse. Overall, the prevalence of anemia among adolescents was found to be 25.5%; 21% for adolescent boys and 30% for adolescent girls. Around 27.1% adolescents reside in the village and 22.6% in the city. Adolescents who consume > 70% energy from being suggested were around 38% respondents. Seventeen percent was classified as thinny adolescent based on IMT indicator. The result on bivariate analyse showed that respondents who were less educated have a significant relation (p < 0.05 with getting anemia (OR=3.8; 95% CI=1.9-7.2. Male adolescents have lower risk to get anemia (OR=0.6; 95% CI 0.5-7.3. Other variables that showed significant relation with anemia were smoking (OR 1.35; 95% CI 1-1.8, breakfast habit (OR 0.6 ;95% CI 0.4-0.9 and sufficient energy consumption (OR 0.7; 95% CI 0.6-0.9. Result of multiple regression logistic test indicate that variables related

Un siglo aún por descubrir en la Historia de España: el siglo V después de Cristo

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Francisco Javier Guzmán Armario

2016-06-01

Full Text Available El siglo V después de Cristo es, sin duda, el más desconocido de la Historia de España. Ello se debe a que, desde fines del siglo XIX, los historiadores han cultivado una imagen de esa centuria marcada por los vicios de la historiografía tradicional que incluso ha llegado a nuestro tiempo. En la actualidad, es necesario recurrir a nuevos planteamientos metodológicos (en este artículo el autor propone cuatro argumentos al respecto y a nuevas perspectivas en Arqueología si se quiere corregir esa deficiencia en un siglo tan importante para la Historia de España.

Iron deficiency and anemia in heart failure.

Science.gov (United States)

Çavuşoğlu, Yüksel; Altay, Hakan; Çetiner, Mustafa; Güvenç, Tolga Sinan; Temizhan, Ahmet; Ural, Dilek; Yeşilbursa, Dilek; Yıldırım, Nesligül; Yılmaz, Mehmet Birhan

2017-03-01

Heart failure is an important community health problem. Prevalence and incidence of heart failure have continued to rise over the years. Despite recent advances in heart failure therapy, prognosis is still poor, rehospitalization rate is very high, and quality of life is worse. Co-morbidities in heart failure have negative impact on clinical course of the disease, further impair prognosis, and add difficulties to treatment of clinical picture. Therefore, successful management of co-morbidities is strongly recommended in addition to conventional therapy for heart failure. One of the most common co-morbidities in heart failure is presence of iron deficiency and anemia. Current evidence suggests that iron deficiency and anemia are more prevalent in patients with heart failure and reduced ejection fraction, as well as those with heart failure and preserved ejection fraction. Moreover, iron deficiency and anemia are referred to as independent predictors for poor prognosis in heart failure. There is strong relationship between iron deficiency or anemia and severity of clinical status of heart failure. Over the last two decades, many clinical investigations have been conducted on clinical effectiveness of treatment of iron deficiency or anemia with oral iron, intravenous iron, and erythropoietin therapies. Studies with oral iron and erythropoietin therapies did not provide any clinical benefit and, in fact, these therapies have been shown to be associated with increase in adverse clinical outcomes. However, clinical trials in patients with iron deficiency in the presence or absence of anemia have demonstrated considerable clinical benefits of intravenous iron therapy, and based on these positive outcomes, iron deficiency has become target of therapy in management of heart failure. The present report assesses current approaches to iron deficiency and anemia in heart failure in light of recent evidence.

Anemia ferropriva em crianças de 6 a 12 meses atendidas na rede pública de saúde do município de Viçosa, Minas Gerais Iron deficiency anemia in 6 to 12-month-old infants attended at the public health service of Viçosa, Minas Gerais, Brazil

Directory of Open Access Journals (Sweden)

Danielle Góes da SILVA

2002-09-01

Full Text Available Este estudo teve como objetivos verificar a prevalência de anemia em lactentes de 6 a 12 meses atendidos na rede pública de saúde do município de Viçosa, MG e analisar alguns possíveis fatores de risco. As informações foram obtidas através de questionário aplicado aos responsáveis pela criança e através da verificação de medidas antropométricas e da dosagem de hemoglobina por hemoglobinômetro portátil. No diagnóstico de anemia, utilizou-se o ponto de corte de 11 g/dL. A prevalência de anemia ferropriva nas 204 crianças estudadas foi 60,8%, e 55,6% dos casos de anemia eram graves. A média da hemoglobina foi 9,28±1,07 nos anêmicos e 12,07±0,89 mg/dL nos não-anêmicos. A baixa escolaridade paterna e a idade materna mostraram associação estatística com a anemia (pThis study aimed at verifying the prevalence of anemia in 6 to 12-month-old infantsattended at the public health service of the city of Viçosa, state of Minas Gerais, and analyzing some possible risk factors. Information was obtained through questionnaire applied to those responsible for the infants and through the verification of the anthropometric measures and the hemoglobin dosage by portable hemoglobinometer. In diagnosing anemia, a 11g/dL cutoff point was used. The prevalence of iron deficiency anemia in a total of 204 infants reached 60.8%, and 55.6% of the cases of anemia were serious. The hemoglobin average was 9.28±1.07 mg/dL in anemic infants, and 12.07± 0.89 mg/dL in non-anemic ones. The father's low school level and the mother's age showed statistical association with anemia (p<0.05. A high prevalence and severity of the anemia was found, emphasizing the need for prevention and control of this disease in the city of Viçosa.

EVALUACIÓN DE REQUERIMIENTOS NUTRICIONALES EN VIVERO DE ESPECIES TROPICALES EMPLEADAS EN SILVICULTURA URBANA

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David Andrés Herrera Ramírez

Full Text Available La fertilización es determinante del crecimiento y desarrollo de árboles urbanos. Por ello, estudiamos, mediante la técnica del elemento faltante, los requerimientos nutricionales de cinco especies tropicales usadas en silvicultura urbana (Tabebuia chrysantha, Margaritaria nobilis, Hamelia patens, Apeiba aspera, Cupania americana. Se encontró algunas especies sensibles a la deficiencia de nitrógeno y otras a la deficiencia de azufre. El grupo de T. chrysanta, M. nobilis y H. patens mostró alta sensibilidad a la deficiencia de nitrógeno, mientras que C. americana y A. aspera presentaron sensibilidad a la deficiencia de azufre, representada en menor crecimiento promedio para todas las variables evaluadas: altura, diámetro en el cuello de la raíz, materia seca radical y materia seca aérea. Las representaciones HJ-Biplot, utilizadas para caracterizar la respuesta por especie a cada tratamiento en todas las unidades experimentales, evidenciaron los bajos rendimientos en crecimiento para las deficiencias en nitrógeno y azufre. El desbalance de bases calcio/magnesio y magnesio/potasio afectó el crecimiento en altura de todas las especies, evidenciado en los altos crecimientos obtenidos para los tratamientos deficientes en calcio y magnesio. Debido a esto, las fórmulas nutricionales utilizadas en vivero deben reajustarse a las exigencias individuales de las especies, para producir mejores árboles para la ciudad.

Severe combined immunodeficiency (SCID) presenting with neonatal aplastic anemia.

Science.gov (United States)

Scott, Angela; Glover, Jason; Skoda-Smith, Suzanne; Torgerson, Troy R; Xu, Min; Burroughs, Lauri M; Woolfrey, Ann E; Fleming, Mark D; Shimamura, Akiko

2015-11-01

Aplastic anemia in the neonate is rare. We report a case of severe combined immunodeficiency (SCID) presenting with neonatal aplastic anemia. This report highlights the importance of considering SCID early in the evaluation of neonatal aplastic anemia prior to the development of infectious complications. © 2015 Wiley Periodicals, Inc.

Anemia: monosymptomatic celiac disease. A report of 3 cases

NARCIS (Netherlands)

Depla, A. C.; Bartelsman, J. F.; Mulder, C. J.; Tytgat, G. N.

1990-01-01

Patients with monosymptomatic celiac disease (CD) can escape diagnosis for a long period. Anemia is a common finding in CD, although anemia as the sole symptom is relatively unknown. We report on three patients who presented with iron deficiency anemia and no other symptom, in whom CD was considered

Observação de anemia hemolítica auto-imune em artrite reumatóide Observation of autoimmune hemolytic anemia in rheumatoid arthritis

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Ricardo A. S. Souza

2003-01-01

Full Text Available Artrite reumatóide é uma doença difusa do tecido conjuntivo que se caracteriza pelo acometimento articular e sistêmico. Disfunções hematológicas como anemia ocorrem em até 65% dos pacientes, sendo a anemia das doenças crônicas a forma mais comum. A anemia hemolítica auto-imune pode estar associada à difusa do tecido conjuntivo, sendo classicamente associada ao lúpus eritematoso sistêmico e fazendo parte dos seus critérios de classificação. A presença de anemia hemolítica auto-imune em artrite reumatóide é relatada raramente na literatura e os mecanismos etiopatogênicos para o seu desenvolvimento ainda não estão esclarecidos. Descrevemos um caso de artrite reumatóide no adulto e outro de artrite reumatóide juvenil que desenvolveram anemia hemolítica auto-imune e discutimos os prováveis mecanismos etiopatogênicos envolvidos.Rheumatoid arthritis is a connective tissue disease characterized by articular and systemic involvement. Hematological abnormalities such as anemia may occur in up to 65% of the patients, with chronic disease anemia being the commonest form. Autoimmune hemolytic anemia can be associated with different connective tissue diseases, particularly systemic lupus erythematosus and it is part of its classification criteria. On the other hand, the presence of autoimmune hemolytic anemia in rheumatoid arthritis has rarely been described in the literature and the pathogenic mechanisms for its development remain unclear. We describe here a case of rheumatoid arthritis and another of juvenile rheumatoid arthritis that developed to autoimmune hemolytic anemia and present the probable etiopathogenic mechanisms.

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... Learn more about participating in a clinical trial . View all trials from ClinicalTrials.gov . Visit Children and Clinical ... Resources NHLBI resources Your Guide to Anemia [PDF, 1. ...

Signaling Pathways in Pathogenesis of Diamond Blackfan Anemia

Science.gov (United States)

2015-12-01

AWARD NUMBER: W81XWH-12-1-0590 TITLE: SIGNALING PATHWAYS IN PATHOGENESIS OF DIAMOND BLACKFAN ANEMIA PRINCIPAL INVESTIGATOR: KATHLEEN M...SUBTITLE 5a. CONTRACT NUMBER W81XWH-12-1-0590 SIGNALING PATHWAYS IN PATHOGENESIS OF DIAMOND BLACKFAN ANEMIA 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER...Unlimited 13. SUPPLEMENTARY NOTES None 14. ABSTRACT: Diamond Blackfan Anemia (DBA) is a disorder that results in pure red cell aplasia, congenital

Hematocrit, anemia, and arm preference for blood sample collection ...

African Journals Online (AJOL)

Background: Anemia in pregnancy is a common cause of maternal morbidity and mortality in developing countries. Regular review of hematocrit (HCT) and anemia patterns in pregnancy is necessary in our environment. Aim: The aim was to determine the average HCT, prevalence, and pattern of anemia, as well the arm ...

The Effects of Anemia on Pregnancy Outcome in Patients with Pyelonephritis

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Sarah K. Dotters-Katz

2013-01-01

Full Text Available Objective. Pyelonephritis is a common infectious morbidity of pregnancy. Though anemia is commonly associated with pyelonephritis, there are little data describing the effect of pyelonephritis with anemia on pregnancy outcomes. The purpose of this study was to further assess the association of anemia with infectious morbidity and pregnancy complications among women with pyelonephritis. Study Design. We conducted a retrospective cohort study of pregnant women admitted to Duke University Hospital between July 2006 and May 2012 with pyelonephritis. Demographic, laboratory, and clinical data from the subject’s pregnancy and hospitalizations were analyzed. Patients with pyelonephritis and anemia (a hematocrit < 32 were compared to those without anemia. Descriptive statistics were used to compare the two groups. Results. 114 pregnant women were admitted with pyelonephritis and 45 (39.5% had anemia on admission. There was no significant difference in age, race, preexisting medical conditions, or urine bacterial species between patients with anemia and those without. Women with anemia were more likely to deliver preterm (OR 3.3 (95% CI 1.07, 11.4, . When controlling for race and history of preterm delivery, women with anemia continued to have increased odds of preterm birth (OR 6.0, CI 1.4, 35, . Conclusion. Women with pyelonephritis and anemia are at increased risk for preterm delivery.

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... making new blood cells. Visit our Aplastic Anemia Health Topic to learn more. Read ... to review family history, lifestyle, unhealthy environments, or other factors that increase your risk of ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... complications, including heart failure and development delays in children. Explore this Health ... red blood cells. Iron-deficiency anemia usually develops over time because your body’s intake of iron ...

Immune hemolytic anemia

Science.gov (United States)

... intravenous immunoglobulin (IVIG) or removal of the spleen (splenectomy) may be considered. You may receive treatment to ... need special treatment. In most people, steroids or splenectomy can totally or partially control anemia.

Una causa infrecuente de convulsión hipocalcémica: raquitismo congénito. Caso clínico

OpenAIRE

Karabel, Duran; Karabel, Musemma; Yilmaz, Ayse Esra; Tas, Tugba; Karayel, Metin

2012-01-01

La deficiencia de vitamina D y el raquitismo son problemas de salud importantes en los países en desarrollo. El raquitismo congénito es una forma infrecuente de raquitismo. La deficiencia materna de vitamina D es el factor de riesgo más importante para la deficiencia de vitamina D y el raquitismo en los recién nacidos y lactantes. Presentamos el caso de un niño de 2 meses de edad, con convulsiones durante su hospitalización por neumonía. Se diagnosticó raquitismo congénito asociado a deficien...

Prevalence and association of post-renal transplant anemia

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Hesham Elsayed

2012-01-01

Full Text Available In some renal allograft recipients, anemia persists or develops following transplantation. Anemia is associated with pre-operative blood loss and allograft dysfunction, including delayed graft function, acute rejection and chronic allograft dysfunction. To study the prevalence and association of post-renal transplant anemia, we studied 200 renal transplant recipients; 131 (65.5% patients were males and 69 (34.5% patients were females, and age ranged from 17 to 67 years, with a mean of 37.7 ± 10.8 years. All patients were receiving cyclosporine, prednisolone and mycophenolate mofetil (MMF. Complete blood count was done at two times: three and six months post-renal transplant. There were 74% anemic patients three months after renal transplantation and 45% anemic patients six months after renal transplantation. High creatinine value, female gender, delayed graft function, episodes of acute rejection, perioperative blood loss and infections were the only significant independent risk factors for prevalence of anemia post-renal transplant. In our study, we did not find an association between MMF and cyclosporine nor angiotensin-converting enzyme inhibitors (ACEIs or angiotensin receptors blocker (ARBs with anemia. This study demonstrates that anemia is a common complication during the first six months after kidney transplantation, with several risk factors precipitating this complication.

Association of mild anemia with cognitive, functional, mood and quality of life outcomes in the elderly: the "Health and Anemia" study.

Directory of Open Access Journals (Sweden)

Ugo Lucca

Full Text Available BACKGROUND: In the elderly persons, hemoglobin concentrations slightly below the lower limit of normal are common, but scant evidence is available on their relationship with significant health indicators. The objective of the present study was to cross-sectionally investigate the association of mild grade anemia with cognitive, functional, mood, and quality of life (QoL variables in community-dwelling elderly persons. METHODS: Among the 4,068 eligible individuals aged 65-84 years, all persons with mild anemia (n = 170 and a randomly selected sample of non-anemic controls (n = 547 were included in the study. Anemia was defined according to World Health Organization (WHO criteria and mild grade anemia was defined as a hemoglobin concentration between 10.0 and 11.9 g/dL in women and between 10.0 and 12.9 g/dL in men. Cognition and functional status were assessed using measures of selective attention, episodic memory, cognitive flexibility and instrumental and basic activities of daily living. Mood and QoL were evaluated by means of the Geriatric Depression Scale-10, the Short-Form health survey (SF-12, and the Functional Assessment of Cancer Therapy-Anemia. RESULTS: In univariate analyses, mild anemic elderly persons had significantly worse results on almost all cognitive, functional, mood, and QoL measures. In multivariable logistic regressions, after adjustment for a large number of demographic and clinical confounders, mild anemia remained significantly associated with measures of selective attention and disease-specific QoL (all fully adjusted p<.046. When the lower limit of normal hemoglobin concentration according to WHO criteria was raised to define anemia (+0.2 g/dL, differences between mild anemic and non anemic elderly persons tended to increase on almost every variable. CONCLUSIONS: Cross-sectionally, mild grade anemia was independently associated with worse selective attention performance and disease-specific QoL ratings.

Impacto económico de la anemia en el Perú

OpenAIRE

Alcázar, Lorena

2012-01-01

El Perú es el país más afectado por la anemia de toda Sudamérica (solo igual que Guyana) de acuerdo a la Organización Mundial de la Salud. Afecta a más del 50% de los niños en edad preescolar, al 42% de madres gestantes y al 40% de las mujeres en edad fértil que no están gestando. Estos niveles de prevalencia en cada grupo poblacional lo ubican en una situación comparable a la de la mayoría de países del África. No obstante su importancia, no se toma conciencia de la magnitud del problema y d...

STUDY OF ANEMIA IN ADOLESCENT SCHOOL GIRLS OF BHOPAL

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Rakesh Kakkar

2011-06-01

Full Text Available Background: Iron-deficiency anemia is the most common form of malnutrition, early intervention during adolescence (girls can prevent high morbidity and mortality of these future mothers. Objectives: To study prevalence & factors contributing to anaemia among adolescent school girls. Material and Methods: Area or region addressed – Iron deficiency anemia in adolescent girls. Present study was conducted among 317 adolescent (10-19Yrs government schoolgirls of Bhopal city from June2005-July2006. Three study groups were selected from three different girls’ school by random sampling method. Statistical analysis was done with SPSS. Result & Conclusion: Overall prevalence was 58.4% among adolescent schoolgirls. Prevalence of anemia was dependent on the knowledge about prevention of anemia, literacy level, food habits, birth order & also frequency of Iron rich source viz. green leafy vegetable & non vegetarian diet. While there was no significant relation of anemia with duration of menstrual flow but there was significant (P<0.05 difference in number of anaemic cases with age at menarche i.e. with higher age at menarche; there was more chances of anemia. Level of anemia was higher (p<0.05 in early adolescent (10 -13 Years age group (81% as compared to middle (58.3% and late adolescent (17-19 years age group girls (48.7%.

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... improved health for people with iron-deficiency anemia. Recipient Epidemiology Donor Studies program findings help to protect blood donors . NHLBI’s Recipient Epidemiology Donor Studies (REDS) program , which began in ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... also often take other medicines—such as proton pump inhibitors, anticoagulants, or blood thinners—that may cause iron-deficiency anemia. Proton pump inhibitors interfere with iron absorption, and blood thinners ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... lead to iron-deficiency anemia include: End-stage kidney failure, where there is blood loss during dialysis. People who have chronic kidney disease also often take other medicines—such as ...

Sideropenic anemia in preschool children and risk factors

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Stojanović Dušica

2006-01-01

Full Text Available INTRODUCTION: Sideropenic anemia is one of the most common nutritional disorders in the world. The children are at higher risk of iron deficiency than adults due to their rapid growth during infancy and relatively higher requirements of iron. OBJECTIVE: The objective of our study was to investigate the prevalence of sideropenic anemia in pre-school children and relevant risk factors. METHOD: Study on sideropenic anemia of preschool children was performed in Zaječar Municipality in 2003. Subjects: all children, age 6-7 years, who lived in the Zaječar Municipality (554 children. The investigation included: interview of children's parents and laboratory analysis of blood. RESULTS: The frequency of sideropenic anemia was 5.23% in tested children (hemoglobin level less than 11g/dl. Sex and place of residence had no significant impact on hemoglobin concentration in blood of children. Likewise, social status and education of parents had no significant impact on iron deficiency anemia. Higher incidence of infections was found in children with lower hemoglobin concentration in blood (p<0.05. It made no difference if children attended the kindergarten or not. Nutrition of children in kindergarten does not correct domestic nutrition, which should be one of its basic roles. CONCLUSION: Since sideropenic anemia gives rise to serious health problems, such as poor cognitive and motor development and behavioral problems, it is important to take corrective measures regarding domestic and social nutrition of children. Therefore, it is necessary to take action in preventing the sideropenic anemia and provide normal growth and development.

APLASTIC ANEMIA ET CAUSA OF SUSPECT VIRAL HEPATITIS INFECTION: A CASE REPORT

OpenAIRE

I Wayan Wawan Lismana

2014-01-01

Aplastic anemia is anemia that occurs because of a failure of hematopoiesis is relatively rarebut can be life threatening. The cause of aplastic anemia itself is still largely unknown oridiopathic. Minority of cases mainly due to a virus infection, one of which is viral hepatitishas long been known to cause symptoms of aplastic anemia. This report discusses thesuspected aplastic anemia caused by hepatitis virus infection. Course of the disease or theprognosis of aplastic anemia varies, but a ...

Assessment of anemia during CT pulmonary angiography

International Nuclear Information System (INIS)

Jung, Caroline; Groth, Michael; Bley, Thorsten A.; Henes, Frank O.; Treszl, András; Adam, Gerhard; Bannas, Peter

2012-01-01

Objectives: Anemia is associated with increased mortality in patients with acute symptomatic pulmonary embolism (PE). The purpose of this study was to evaluate the feasibility of Hounsfield unit (HU) measurements on the single unenhanced trigger slice of pulmonary CT angiography scans for diagnosis of anemia. Material and Methods: 150 consecutive patients (median age 64 ± 16 years) with suspected PE underwent pulmonary CT angiography. Two radiologists, blinded to laboratory results, performed HU measurements in the single unenhanced trigger scan independently by region-based analysis (ROI). HU values from ascending and descending aorta and the calculated mean of both were correlated with serum hemoglobin levels. Inter- and intraobserver variability was determined for HU measurements, and ROC analysis was performed for diagnosis of anemia. Calculated linear models were used to assess formulas for estimation of hemoglobin levels from HU measurements. Results: HU measurements revealed high intra- and interrater reliability (ICC > 0.981 and ICC > 0.965, respectively). Calculated mean HU values showed a strong correlation with serum hemoglobin levels (r = 0.734), which allowed generation of different formulas for calculation of hemoglobin levels from HU measurements. ROC analyses confirmed a high sensitivity (80.4 for men; 91.3 for women) and specificity (84.0 for men; 84.9 for women) for diagnosing anemia. Conclusion: Diagnosis of anemia and quantification of hemoglobin levels upon a single unenhanced trigger scan of pulmonary CT angiography is feasible. We suggest disclosing the anemic state in the radiological report, independent of the presence of PE, since anemia carries increased risks of morbidity and mortality.

Assessment of anemia during CT pulmonary angiography

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Jung, Caroline, E-mail: cjung@uke.de [Department of Diagnostic and Interventional Radiology, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg (Germany); Groth, Michael; Bley, Thorsten A.; Henes, Frank O. [Department of Diagnostic and Interventional Radiology, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg (Germany); Treszl, András [Department of Medical Biometry and Epidemiology, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg (Germany); Adam, Gerhard; Bannas, Peter [Department of Diagnostic and Interventional Radiology, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg (Germany)

2012-12-15

Objectives: Anemia is associated with increased mortality in patients with acute symptomatic pulmonary embolism (PE). The purpose of this study was to evaluate the feasibility of Hounsfield unit (HU) measurements on the single unenhanced trigger slice of pulmonary CT angiography scans for diagnosis of anemia. Material and Methods: 150 consecutive patients (median age 64 ± 16 years) with suspected PE underwent pulmonary CT angiography. Two radiologists, blinded to laboratory results, performed HU measurements in the single unenhanced trigger scan independently by region-based analysis (ROI). HU values from ascending and descending aorta and the calculated mean of both were correlated with serum hemoglobin levels. Inter- and intraobserver variability was determined for HU measurements, and ROC analysis was performed for diagnosis of anemia. Calculated linear models were used to assess formulas for estimation of hemoglobin levels from HU measurements. Results: HU measurements revealed high intra- and interrater reliability (ICC > 0.981 and ICC > 0.965, respectively). Calculated mean HU values showed a strong correlation with serum hemoglobin levels (r = 0.734), which allowed generation of different formulas for calculation of hemoglobin levels from HU measurements. ROC analyses confirmed a high sensitivity (80.4 for men; 91.3 for women) and specificity (84.0 for men; 84.9 for women) for diagnosing anemia. Conclusion: Diagnosis of anemia and quantification of hemoglobin levels upon a single unenhanced trigger scan of pulmonary CT angiography is feasible. We suggest disclosing the anemic state in the radiological report, independent of the presence of PE, since anemia carries increased risks of morbidity and mortality.

Anemia and hemoglobin levels among Indigenous Xavante children, Central Brazil.

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Ferreira, Aline Alves; Santos, Ricardo Ventura; Souza, July Anne Mendonça de; Welch, James R; Coimbra, Carlos E A

2017-01-01

To evaluate the prevalence of anemia, mean hemoglobin levels, and the main nutritional, demographic, and socioeconomic factors among Xavante children in Mato Grosso State, Brazil. A survey was conducted with children under 10 years of age in two indigenous Xavante communities within the Pimentel Barbosa Indigenous Reserve. Hemoglobin concentration levels, anthropometric measurements, and socioeconomic/demographic data were collected by means of clinical measurements and structured interviews. The cut-off points recommended by the World Health Organization were used for anemia classification. Linear regression analyses with hemoglobin as the outcome and Poisson regression with robust variance and with the presence or absence of anemia as outcomes were performed (95%CI). Lower mean hemoglobin values were observed in children under 2 years of age, without a significant difference between sexes. Anemia was observed among 50.8% of children overall, with the highest prevalence among children under 2 years of age (77.8%). Age of the child was inversely associated with the occurrence of anemia (adjusted PR = 0.60; 95%CI 0.38-0.95) and mean hemoglobin values increased significantly with age. Greater height-for-age z-score values reduced the probability of having anemia by 1.8 times (adjusted PR = 0.59; 95%CI 0.34-1.00). Presence of another child with anemia within the household increased the probability of the occurrence of anemia by 52.9% (adjusted PR = 1.89; 95%CI 1.16-3.09). Elevated levels of anemia among Xavante children reveal a disparity between this Indigenous population and the national Brazilian population. Results suggest that anemia is determined by complex and variable relationships between socioeconomic, sociodemographic, and biological factors.

Multivariable Discriminant Analysis for the Differential Diagnosis of Microcytic Anemia

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Eloísa Urrechaga

2013-01-01

Full Text Available Introduction. Iron deficiency anemia and thalassemia are the most common causes of microcytic anemia. Powerful statistical computer programming enables sensitive discriminant analyses to aid in the diagnosis. We aimed at investigating the performance of the multiple discriminant analysis (MDA to the differential diagnosis of microcytic anemia. Methods. The training group was composed of 200 β-thalassemia carriers, 65 α-thalassemia carriers, 170 iron deficiency anemia (IDA, and 45 mixed cases of thalassemia and acute phase response or iron deficiency. A set of potential predictor parameters that could detect differences among groups were selected: Red Blood Cells (RBC, hemoglobin (Hb, mean cell volume (MCV, mean cell hemoglobin (MCH, and RBC distribution width (RDW. The functions obtained with MDA analysis were applied to a set of 628 consecutive patients with microcytic anemia. Results. For classifying patients into two groups (genetic anemia and acquired anemia, only one function was needed; 87.9% β-thalassemia carriers, and 83.3% α-thalassemia carriers, and 72.1% in the mixed group were correctly classified. Conclusion. Linear discriminant functions based on hemogram data can aid in differentiating between IDA and thalassemia, so samples can be efficiently selected for further analysis to confirm the presence of genetic anemia.

Retinal phlebitis associated with autoimmune hemolytic anemia.

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Chew, Fiona L M; Tajunisah, Iqbal

2009-01-01

To describe a case of retinal phlebitis associated with autoimmune hemolytic anemia. Observational case report. A 44-year-old Indian man diagnosed with autoimmune hemolytic anemia presented with a 1-week history of blurred vision in both eyes. Fundus biomicroscopy revealed bilateral peripheral retinal venous sheathing and cellophane maculopathy. Fundus fluorescent angiogram showed bilateral late leakage from the peripheral venous arcades and submacular fluid accumulation. The retinal phlebitis resolved following a blood transfusion and administration of systemic steroids. Retinopathy associated with autoimmune hemolytic anemia is not well known. This is thought to be the first documentation of retinal phlebitis occurring in this condition.

Reticulocyte maturity indices in iron deficiency anemia

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Muriel Wollmann

2014-01-01

Full Text Available Objective: The aim of this study was to analyze the reticulocyte maturity indices (low, medium, and high fluorescence ratios in iron deficient 1- to 6-year-old children, and identify the prevalence of iron deficiency anemia in this population. Methods: The present study included 39 subjects, divided into two groups: control subjects (n = 33, and subjects with iron deficiency anemia (n = 6. The results were analyzed by Student's t-test for comparison of means. Differences were considered significant when two-tailed p-value < 0.05. Results: Subjects with iron deficiency anemia presented increases in the proportion of mean (10.3 ± 4.7% vs. 6.0 ± 3.4%; p-value = 0.003, and high fluorescence reticulocytes (2.3 ± 0.87% vs. 0.9 ± 0.9%; p-value = 0.03 compared to the control group. The prevalence of anemia in this population was 15% (n = 6. Conclusion: The indices related to immaturity of reticulocytes are higher in the presence of iron deficiency, thus demonstrating a deficiency in the raw material to form hemoglobin and are, therefore, possible early markers of iron deficiency and anemia. We emphasize the need to standardize these indices for use in clinical practice and lab test results.

Influencia del tipo y granulometría del sustrato en la depuración de las aguas residuales por el sistema de humedales artificiales de flujo vertical y horizontal

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Pidre Bocardo, Juan Ramón

2010-01-01

La depuración de las aguas residuales es uno de lo graves problemas ambientales que aún nos quedan por resolver. Aunque buena parte de la población ya tiene cubierta dicha necesidad, es en las poblaciones pequeñas donde son más altas las cifras de la deficiencia de este servicio. Una de las tecnologías disponibles para la depuración de las aguas residuales en pequeñas ponlaciones que más grado de implatación está teniendo a nivel mundial es la conocida como Humedales Artificiales. La...

Iron-Deficiency Anemia

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Full Text Available ... an increased risk for iron-deficiency anemia because of your age, unhealthy environments, family ... 12 months, especially if they are fed only breast milk or are fed formula that is not fortified ...

Representaciones sociales relacionadas a la anemia en niños menores de tres años en comunidades Awajún y Wampis, Perú

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Julio Mayca-Pérez

Full Text Available RESUMEN Objetivos Conocer las representaciones sociales de las comunidades awajún y wampis en torno a síntomas y tratamiento de la anemia en niños menores de 03 años, la relación con sus simbolismos, constructos y tipo de alimentación. Materiales y métodos Estudio cualitativo realizado entre junio y agosto del 2015, en los distritos de Río Santiago, Cenepa y Nieva (región Amazonas, Perú; que incluyó entrevistas en profundidad (EP para personal de salud, autoridades de la comunidad y padres de familia, y grupos focales (GF para madres de familia. Resultados Se realizaron 38 EP y 13 GF. La población no tuvo un significado claro sobre la anemia, ni manejaba la misma descripción del personal de salud; sino que lo relacionaba con una sintomatología en base a sus representaciones sociales y manifestaciones culturales. Esto aplicaba en la decisión de los padres por el tratamiento a optar, no necesariamente, lo indicado por el personal de salud, y que prefieren el consumo de ciertos alimentos que podrían curar el putsumat. El acudir al establecimiento de salud o utilizar multimicronutrientes no era entonces su primera opción de tratamiento. Conclusiones Las representaciones sociales y prácticas tradicionales continúan existiendo y poseen sistemas interpretativos sobre la salud, la enfermedad y su manejo, con lógicas, sentidos y coherencia según grupo cultural. El putsumat o putsuju es un modelo interpretativo equivalente para la anemia, con una sintomatología presentada por los niños con palidez, delgadez, cansancio, sustentado en el sistema cultural simbólico de las poblaciones awajún y wampis.

Infección nasal por Hirudo medicinalis y breve revisión del tema

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María Beltran

1997-07-01

Full Text Available Se presentan dos casos de infección nasal por Hirudo medicinalis "sanguijuela medicinal". Estos gusanos se obtuvieron de las fosas nasales de dos niños, uno de ellos, del caserio Zapatero, Coñumbuqui, Lamas (San Martín, Perú y el otro de San Francisco (Ayacucho, Perú, de 6 y 1,5 años de edad, respectivamente. El tamaño de las sanguijuelas fue de 2.5 y 6 cm. en cada uno de los casos. Las sanguijuelas tienen importancia en la salud pública por que pueden producir anemia grave, asfixia y la muerte.

Fanconi anemia proteins in telomere maintenance.

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Sarkar, Jaya; Liu, Yie

2016-07-01

Mammalian chromosome ends are protected by nucleoprotein structures called telomeres. Telomeres ensure genome stability by preventing chromosome termini from being recognized as DNA damage. Telomere length homeostasis is inevitable for telomere maintenance because critical shortening or over-lengthening of telomeres may lead to DNA damage response or delay in DNA replication, and hence genome instability. Due to their repetitive DNA sequence, unique architecture, bound shelterin proteins, and high propensity to form alternate/secondary DNA structures, telomeres are like common fragile sites and pose an inherent challenge to the progression of DNA replication, repair, and recombination apparatus. It is conceivable that longer the telomeres are, greater is the severity of such challenges. Recent studies have linked excessively long telomeres with increased tumorigenesis. Here we discuss telomere abnormalities in a rare recessive chromosomal instability disorder called Fanconi Anemia and the role of the Fanconi Anemia pathway in telomere biology. Reports suggest that Fanconi Anemia proteins play a role in maintaining long telomeres, including processing telomeric joint molecule intermediates. We speculate that ablation of the Fanconi Anemia pathway would lead to inadequate aberrant structural barrier resolution at excessively long telomeres, thereby causing replicative burden on the cell. Published by Elsevier B.V.

[Equine Infectious Anemia (EIA)].

Science.gov (United States)

Kaiser, A; Meier, H P; Straub, R; Gerber, V

2009-04-01

Equine Infectious Anemia (EIA) is a reportable, eradicable epizootic disease caused by the equine lentivirus of the retrovirus family which affects equids only and occurs worldwide. The virus is transmitted by blood, mainly by sanguivorous insects. The main symptoms of the disease are pyrexia, apathy, loss of body condition and weight, anemia, edema and petechia. However, infected horses can also be inapparent carriers without any overt signs. The disease is diagnosed by serological tests like the Coggins test and ELISA tests. Presently, Switzerland is offi cially free from EIA. However, Switzerland is permanently at risk of introducing the virus as cases of EIA have recently been reported in different European countries.

An analysis of anemia and child mortality

NARCIS (Netherlands)

Brabin, B. J.; Premji, Z.; Verhoeff, F.

2001-01-01

The relationship of anemia as a risk factor for child mortality was analyzed by using cross-sectional, longitudinal and case-control studies, and randomized trials. Five methods of estimation were adopted: 1) the proportion of child deaths attributable to anemia; 2) the proportion of anemic children

Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease

DEFF Research Database (Denmark)

Nielsen, Ole Haagen; Ainsworth, Mark; Coskun, Mehmet

2015-01-01

Anemia is the most frequent complication of inflammatory bowel disease (IBD), but anemia, mostly due to iron deficiency, has long been neglected in these patients. The aim was to briefly present the pathophysiology, followed by a balanced overview of the different forms of iron replacement...... available, and subsequently, to perform a systematic review of studies performed in the last decade on the treatment of iron-deficiency anemia in IBD. Given that intravenous therapies have been introduced in the last decade, a systematic review performed in PubMed, EMBASE, the Cochrane Library......, and the websites of WHO, FDA, and EMA covered prospective trials investigating the management of iron-deficiency anemia in IBD published since 2004. A total of 632 articles were reviewed, and 13 articles (2906 patients) with unique content were included. In general, oral supplementation in iron-deficiency anemia...

Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells.

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Van Wassenhove, Lauren D; Mochly-Rosen, Daria; Weinberg, Kenneth I

2016-09-01

Maintenance of the hematopoietic stem cell (HSC) compartment depends on the ability to metabolize exogenously and endogenously generated toxins, and to repair cellular damage caused by such toxins. Reactive aldehydes have been demonstrated to cause specific genotoxic injury, namely DNA interstrand cross-links. Aldehyde dehydrogenase 2 (ALDH2) is a member of a 19 isoenzyme ALDH family with different substrate specificities, subcellular localization, and patterns of expression. ALDH2 is localized in mitochondria and is essential for the metabolism of acetaldehyde, thereby placing it directly downstream of ethanol metabolism. Deficiency in ALDH2 expression and function are caused by a single nucleotide substitution and resulting amino acid change, called ALDH2*2. This genetic polymorphism affects 35-45% of East Asians (about ~560 million people), and causes the well-known Asian flushing syndrome, which results in disulfiram-like reactions after ethanol consumption. Recently, the ALDH2*2 genotype has been found to be associated with marrow failure, with both an increased risk of sporadic aplastic anemia and more rapid progression of Fanconi anemia. This review discusses the unexpected interrelationship between aldehydes, ALDH2 and hematopoietic stem cell biology, and in particular its relationship to Fanconi anemia. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Comprehensive Review of Preschool Age Anemia in the Pacific Island Jurisdictions.

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Lin, Tiffany F; Huang, James N; Cash, Haley L

2017-12-01

Anemia can be an indicator of poor nutrition and health, and it can have significant consequences. Children are disproportionately affected by anemia. This comprehensive review summarizes the available literature on anemia prevalence in young children in the islands of the Oceania region. The anemia prevalence, the criteria used for diagnosis, the date the data was reported, and the types of samples collected were reviewed. Anemia prevalence estimates were reported for eighteen of the Pacific Island Jurisdictions. From the fifteen data sources that were evaluable, anemia prevalence ranged from 12.3% to over 70%. A major limitation in the data is a lack of representative primary data from many of the jurisdictions in the region. Prevalance estimates reported for those jurisdictions are estimated by regression analysis from the World Health Organization (WHO). Moreover, the primary data available does not use standardized reporting criteria. Nevertheless, this review serves as a new baseline for further investigations on the prevalence of anemia and a baseline for evaluating public health prevention and treatment measures to detect and improve anemia prevalence in the Pacific.

Management of Anemia in Patients with Inflammatory Bowel Disease (IBD).

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Patel, Dhruvan; Trivedi, Chinmay; Khan, Nabeel

2018-03-01

Anemia is the most common complication as well as an extra intestinal manifestation of inflammatory bowel disease (IBD). It is associated with a significant impact on patient's quality of life (QoL); as well it represents a common cause of frequent hospitalization, delay of hospital inpatient discharge and overall increased healthcare burden. In spite of all these, anemia is still often underdiagnosed and undertreated. Our aim in this review is to provide a pathway for physicians to help them achieve early diagnosis as well as timely and appropriate treatment of anemia which in turn would hopefully reduce the prevalence and subsequent complications of this condition among IBD patients. The etiology of anemia among IBD patients is most commonly due to iron deficiency anemia (IDA) followed by anemia of chronic disease. Despite this, more than a third of anemic ulcerative colitis (UC) patients are not tested for IDA and among those tested and diagnosed with IDA, a quarter are not treated with iron replacement therapy. A new algorithm has been validated to predict who will develop moderate to severe anemia at the time of UC diagnosis. While oral iron is effective for the treatment of mild iron deficiency-related anemia, the absorption of iron is influenced by chronic inflammatory states as a consequence of the presence of elevated levels of hepcidin. Also, it is important to recognize that ferritin is elevated in chronic inflammatory states and among patients with active IBD, ferritin levels less than 100 are considered to be diagnostic of iron deficiency. Newer formulations of intra-venous (IV) iron have a good safety profile and can be used for replenishment of iron stores and prevention of iron deficiency in the future. Routine screening for anemia is important among patients with IBD. The cornerstone for the accurate management of anemia in IBD patients lies in accurately diagnosing the type of anemia. All IBD patients with IDA should be considered appropriate for

Iron-Deficiency Anemia

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Full Text Available ... A-Z Clinical Trials Publications and Resources Health Education and Awareness ... If your doctor diagnoses you with iron-deficiency anemia, your treatment will depend on the cause and severity of the condition. Your ...

Iron-Deficiency Anemia

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Full Text Available ... making new blood cells. Visit our Aplastic Anemia Health Topic to learn more. ... recommend that you take iron supplements, also called iron pills or oral iron, by mouth once or several times a ...

Iron-Deficiency Anemia

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Full Text Available ... anemia may cause the following complications: Depression Heart problems. If you do not have enough hemoglobin-carrying red blood cells, your heart has to work harder to move oxygen-rich blood through your ...

Anemia of chronic disease is the more frequent type of anemia seen in patients with chronic idiopathic neutropenia of adults.

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Papadaki, H A; Eliopoulos, D G; Valatas, V; Eliopoulos, G D

2001-04-01

This study describes the frequency and the type of anemia seen in patients with nonimmune chronic idiopathic neutropenia of adults (NI-CINA). We found that NI-CINA patients had low hemoglobin levels and increased serum concentrations of erythropoietin (EPO), tumor necrosis factor-alpha (TNF-alpha), and interleukin-1beta (IL-1beta). The hemoglobin levels correlated positively with the number of circulating neutrophils and inversely with the levels of EPO and TNF-alpha but not of IL-1beta. Anemia, defined as the reduction of the hemoglobin below 12.0 g/dl for women and 13.3 g/dl for men, was found in 23 out of 148 patients studied, a proportion of 15.5%. Two of the anemic patients had iron deficiency anemia (8.7%), 11 had anemia of chronic disease (ACD; 47.8%) presenting with normal or slightly reduced erythrocytic indices, low serum iron, and increased serum ferritin, and the remaining ten had anemia of undefined pathogenesis (AUP; 43.5%) with normal or slightly decreased erythrocytic indices, serum iron ranging from 43 to 88 microg/dl, and ferritin values ranging from 12 to 50 ng/ml. We conclude that ACD is the more frequent type of anemia seen in patients with NI-CINA, and that pro-inflammatory cytokines, notably TNF-alpha, may be involved in the pathogenesis of both ACD and AUP, given that serum levels of the cytokine were significantly increased and that the EPO response to anemia was blunted in these patients. These findings further support our previously reported suggestion for the possible existence, in NI-CINA patients, of an unrecognized low-grade chronic inflammatory process that may be involved in the pathogenesis of the disorder.

Iron status in spanish junior soccer and basketball players. Status en hierro de jugadores de fútbol y baloncesto de la categoría junior.

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Valtueña , Jara

2006-07-01

"registro de consumo de alimentos" durante 7 días consecutivos. El estatus de hierro se evaluó por un completo hemograma, hierro sérico, ferritina, transferritina y TIBC. Resultados: La media de ingesta de hierro fue de 19.74±4.58 mg/día. Los datos analíticos significativos estaban todos entre los rangos de referencia. Los jugadores de baloncesto presentaron una ingesta significativamente superior que los de fútbol (22.1±6.4 y 19.2±3.9 mg/día. Sin embargo, los jugadores de baloncesto presentaron valores inferiores para los hematíes, hemoglobina, hematocrito y de los valores corpusculares medios al compararlos con los jugadores de fútbol. Conclusiones: durante la adolescencia están aumentadas las necesidades de hierro, por lo que los adolescentes deportistas podrían ser un grupo de riesgo de padecer deficiencia de hierro y anemia del deportista. En la presente investigación, la población objeto de estudio presenta unos valores aceptables de status en hierro pero habiendo un 3% de casos con anemia por deficiencia de hierro.

Asociación entre los niveles de zinc intracelular y el estado nutricional de los niños infectados por el virus de la inmunodeficiencia humana (VIH) y los niños expuestos al virus no infectados

OpenAIRE

Gómez G, Erika María; Maldonado C, María Elena; Rojas L, Mauricio; Posada J, Gladys

2015-01-01

Introducción: Desnutrición, retardo en el crecimiento e infecciones oportunistas sobrevienen a alteraciones metabólicas, inmunológicas y gastrointestinales que produce el virus de la inmunodeficiencia humana (VIH). La deficiencia de zinc se ha asociado con deterioro nutricional, falla en el crecimiento y riesgo de infecciones. El objetivo de este estudio fue asociar los niveles de zinc en células mononucleares de sangre periférica (PBMC) con el estado nutricional en niños infectados por el VI...

Iron-Deficiency Anemia

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Iron-Deficiency Anemia

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Iron-Deficiency Anemia

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Iron-Deficiency Anemia

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Iron-Deficiency Anemia

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Iron-Deficiency Anemia

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Iron-Deficiency Anemia

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Iron-Deficiency Anemia

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