WorldWideScience

Sample records for andmed aastatest 1999-2007

  1. Avatud andmed muudavad ühiskonna paremaks / Indrek Petersoo

    Index Scriptorium Estoniae

    Petersoo, Indrek

    2011-01-01

    Riigi poolt kogutavad andmed on kättesaadavad erinevate andmebaaside vahendusel. Riigi eesmärgiks on parandada andmete liikumist ja kasutamist erinevate andmekogude vahel. Lisa: Valitsuse 8 open data printsiipi

  2. United Nations Impact on Child Soldier Use in Eastern Democratic Republic of the Congo: 1999-2007

    Science.gov (United States)

    2008-12-12

    Reuters, 19 June. —. Congo’s Street Kids Could Be Election Winning Group. Reuters, 4 April, 2006. Security Council Report. 2008. Cross Cutting Report...UNITED NATIONS IMPACT ON CHILD SOLDIER USE IN EASTERN DEMOCRATIC REPUBLIC OF THE CONGO : 1999-2007 A thesis presented to the Faculty...To) FEB 2008 – DEC 2008 4. TITLE AND SUBTITLE United Nations Impact on Child Soldier Use in Eastern Democratic Republic of the Congo : (1999-2007

  3. THE BARRIERS FOR PROLIFERATION OF INTERACTIVE TELEVISION (ITV IN AUSTRALIA IN THE PERIOD 1999-2007

    Directory of Open Access Journals (Sweden)

    Maria J. Bora

    2012-04-01

    Full Text Available Interactive television (iTV could well be described as a rising research area. The digitalization of networks, as well as broadband penetration, makes it once again a contemporary issue. However, it can hardly be called an overworked area of Australian television studies. This article assesses multiple reasons behind the Australian failure to adopt this technology in the period 1999-2007. iTV did not open feasible revenue streams for broadcasters. Its role was complementary to the digital TV services offered by current incumbent providers. The interactive potential of the Internet supported by users’ engagement started to fulfil the promises of iTV and offered more collaborative service propositions. Still, at this point, neither TV nor the Internet provides fully viable business models for iTV. Instead there has been a flux of online and offline revenue models and continuing uncertainty about the future of media.

  4. 23andMe: a new two-sided data-banking market model.

    Science.gov (United States)

    Stoeklé, Henri-Corto; Mamzer-Bruneel, Marie-France; Vogt, Guillaume; Hervé, Christian

    2016-03-31

    Since 2006, the genetic testing company 23andMe has collected biological samples, self-reported information, and consent documents for biobanking and research from more than 1,000,000 individuals (90% participating in research), through a direct-to-consumer (DTC) online genetic-testing service providing a genetic ancestry report and a genetic health report. However, on November 22, 2013, the Food and Drug Administration (FDA) halted the sale of genetic health testing, on the grounds that 23andMe was not acting in accordance with federal law, by selling tests of undemonstrated reliability as predictive tests for medical risk factors. Consumers could still obtain the genetic ancestry report, but they no longer had access to the genetic health report in the United States (US). However, this did not prevent the company from continuing its health research, with previously obtained and future samples, provided that consent had been obtained from the consumers concerned, or with health reports for individuals from other countries. Furthermore, 23andMe was granted FDA authorization on February 19, 2015, first to provide reports about Bloom syndrome carrier status, and, more recently, to provide consumers with "carrier status" information for 35 genes known (with high levels of confidence) to cause disease. In this Debate, we highlight the likelihood that the primary objective of the company was probably two-fold: promoting itself within the market for predictive testing for human genetic diseases and ancestry at a low cost to consumers, and establishing a high-value database/biobank for research (one of the largest biobanks of human deoxyribonucleic acid (DNA) and personal information). By dint of this marketing approach, a two-sided market has been established between the consumer and the research laboratories, involving the establishment of a database/DNA biobank for scientific and financial gain. We describe here the profound ethical issues raised by this setup.

  5. Association of allergic rhinitis or asthma with pollen and chemical pollutants in Szeged, Hungary, 1999-2007

    Science.gov (United States)

    Makra, László; Matyasovszky, István; Bálint, Beatrix; Csépe, Zoltán

    2014-07-01

    The effect of biological (pollen) and chemical air pollutants on respiratory hospital admissions for the Szeged region in Southern Hungary is analysed. A 9-year (1999-2007) database includes—besides daily number of respiratory hospital admissions—daily mean concentrations of CO, PM10, NO, NO2, O3 and SO2. Two pollen variables ( Ambrosia and total pollen excluding Ambrosia) are also included. The analysis was performed for patients with chronic respiratory complaints (allergic rhinitis or asthma bronchiale) for two age categories (adults and the elderly) of males and females. Factor analysis was performed to clarify the relative importance of the pollutant variables affecting respiratory complaints. Using selected low and high quantiles corresponding to probability distributions of respiratory hospital admissions, averages of two data sets of each air pollutant variable were evaluated. Elements of these data sets were chosen according to whether actual daily patient numbers were below or above their quantile value. A nonparametric regression technique was applied to discriminate between extreme and non-extreme numbers of respiratory admissions using pollen and chemical pollutants as explanatory variables. The strongest correlations between extreme patient numbers and pollutants can be observed during the pollen season of Ambrosia, while the pollen-free period exhibits the weakest relationships. The elderly group with asthma bronchiale is characterised by lower correlations between extreme patient numbers and pollutants compared to adults and allergic rhinitis, respectively. The ratio of the number of correct decisions on the exceedance of a quantile resulted in similar conclusions as those obtained by using multiple correlations.

  6. Water-level, borehole geophysical log, and water-quality data from wells transecting the freshwater/saline-water interface of the San Antonio segment of the Edwards Aquifer, South-Central Texas, 1999-2007

    Science.gov (United States)

    Lambert, Rebecca B.; Hunt, Andrew G.; Stanton, Gregory P.; Nyman, Michael B.

    2009-01-01

    As a part of a 9-year (1999-2007) study done by the U.S. Geological Survey in cooperation with the San Antonio Water System to improve understanding of the San Antonio segment of the Edwards aquifer, south-central Texas, in and near the freshwater/saline-water transition zone of the aquifer, the U.S. Geological Survey collected water-level, borehole geophysical, and water-quality data during 1999-2007 from 37 wells arranged in nine transects (except for two wells) across the freshwater/saline-water interface of the aquifer. This report presents the data collected and also describes the data-collection, analytical, and quality-assurance methods used. The wells, constructed with casing from land surface into the upper part of the aquifer and completed as open hole in the aquifer, are in Uvalde County (East Uvalde transect), in Medina County (South Medina and Devine wells), in Bexar County (Pitluk, Mission, and San Antonio transects), in Comal and Guadalupe Counties (Tri-County transect), in Comal County (New Braunfels transect), and in Hays County (Fish Hatchery, San Marcos, and Kyle transects). Data collected included continuous water level at 18 wells; fluid electrical conductivity and temperature with depth (fluid profiles) obtained by borehole geophysical logging of 15 wells; discrete (periodic) samples for major ions and trace elements at 36 wells; stable isotopes or stable isotopes and tritium at 27 wells; dissolved gases obtained by pumping (or collecting flow) of 19 wells; and continuous specific conductance and temperature at three of the wells equipped with continuous water-level sensors.

  7. Opinion climates and immigrant political action: A cross-national study of 25 European democracies / Aida Just, Christopher J. Anderson

    Index Scriptorium Estoniae

    Just, Aida

    2014-01-01

    Artiklis esitatakse immigrantide poliitilise tegevuse mudel, mis ühendab individuaalse motivatsiooni olla poliitilised hõivatud kontekstiga, milles see tegevus leiab aset, aluseks 25 riigi (sh Eesti) Euroopa sotsiaaluuringu andmed aastatest 2002 kuni 2010

  8. Profitability of foreign banks in Central and Eastern Europe. Does the entry mode matter? / Olena Havrylchyk, Emilia Jurzyk

    Index Scriptorium Estoniae

    Havrylchyk, Olena

    2011-01-01

    Artikli aluseks on Kesk- ja Ida-Euroopas (sh. Eesti) tegutseva 418 panga andmed aastatest 1993-2004, analüüsitakse, kuidas mõjutavad panga turule sisenemise viis ja emapank panga kasumlikkust. Tabelid

  9. Ethnic diversity, economic and cultural contexts, and social trust: Cross-sectional and longitudinal evidence from European regions, 2002–2010 / Conrad Ziller

    Index Scriptorium Estoniae

    Ziller, Conrad

    2015-01-01

    Artikkel keskendub sisserändest tuleneva etnilise mitmekesisuse ja sotsiaalse usalduse seostele Euroopa riikides (sh. Eesti). Aluseks on Euroopa sotsiaaluuringu andmed aastatest 2002, 2004, 2006, 2008, 2010 ja Euroopa tööjõu-uuringu sisserände andmed

  10. THE URBAN POOR AND HOUSING IN NIGERIA 1999-2007

    African Journals Online (AJOL)

    MRS. EDITH OPO-OLA

    matched by parallel development of infrastructure and social service facilities. Conscious of this gap, the ... countries level of urbanization was 25%, in 1994, it increased to 37% and it is projected to be 57% in ... OBJECTIVES OF STUDY. This study seeks to evaluate the living conditions of the urban poor in Port Harcourt.

  11. Democratization and the national question in Nigeria (1999-2007 ...

    African Journals Online (AJOL)

    The paper argues that competitive political parties and open elections tend to mobilize and politicize regional, ethnic, religious and racial solidarities in divided societies. This again tends to intensify disintegrative processes of fragile states without contributing to their stability or legitimacy - at least, in the short run.

  12. Alzheimer's Disease in the Danish Malnutrition Period 1999-2007

    DEFF Research Database (Denmark)

    Sparre-Sørensen, Maja; Kristensen, Gustav David Westergaard

    2015-01-01

    BACKGROUND: Several studies published over the last few years have shown that malnutrition is a risk factor for developing and worsening Alzheimer's disease (AD) and that a balanced diet can delay the onset of the disease. During the period from January 1999 to January 2007, a statistically...

  13. The ‘political poverty trap’: Bolivia 1999-2007

    OpenAIRE

    Paul Mosley

    2007-01-01

    We analyse the recent wave of political instability in Bolivia in the context of a ‘poverty trap’ model which suggests that elements in a country’s political system, as well as its economic structure, may be instrumental in perpetuating a state of poverty. In Bolivia the costs of adjustment in the recent phase have been very severe, with well over a hundred killed between 1999 and 2007 as a direct consequence of demonstrations against aspects of the globalisation and adjustment process, and a...

  14. Dekonstruktsioon moes ja tekstiilis alates 1980. aastatest / Miina Leesment

    Index Scriptorium Estoniae

    Leesment, Miina

    2010-01-01

    Loomeprojektist "Taashingus", mille alusmaterjaliks on inimeste hüljatud kasutamiskõlblikud kudumid, mis dekonstruktsioonide kaudu saavad uue võimaluse ja värske identiteedi. Ka dekonstruktsioonist Jacques Derrida filosoofias, selle mõjust arhitektuurile ning reflekteerumisest subkultuuridele (näit. punkarid), nende vastasseisust valitsevatele moesuundadele ja vastupidistest mõjudest

  15. The end of the honeymoon: The increasing differentiation of (long-term) unemployment risks in Europe / Martin Heidenreich

    Index Scriptorium Estoniae

    Heidenreich, Martin

    2015-01-01

    Artikkel analüüsib, millistel sotsiaalsetel gruppidel on suurem tõenäosus sattuda töötute hulka praeguse majandus- ja finantskriisi ajal, kusjuures eristatakse lühi- ja pikaajalist töötust. Aluseks EU-SILC andmed 24 Euroopa riigi (sh Eesti) kohta aastatest 2005-2012

  16. Who's at the table? An analysis of ministers' participation in EU Council of Ministers meetings / Carline Howard Grøn, Heidi Houlberg Salomonsen

    Index Scriptorium Estoniae

    Howard Grøn, Caroline

    2015-01-01

    Artiklis analüüsitakse, kuivõrd võtavad liikmesriikide (sh Eesti) esindajad osa Euroopa Liidu Nõukogu istungitest ja kas osavõtjateks on alati ministrid või hoopis kõrged riigiametnikud? Andmed on aastatest 2005-2009

  17. The state of political participation in post-communist democracies: Low but suprisingly little biased citizen engagement / Filip Kostelka

    Index Scriptorium Estoniae

    Kostelka, Filip

    2014-01-01

    Artiklis analüüsitakse poliitilise osaluse taset Kesk- ja Ida-Euroopa postsotsialistlikes demokraatiates (sh Eesti) ning tuuakse võrdlusandmed Lääne-Euroopa vanade demokraatiatega, aluseks Euroopa sotsialuuringu andmed aastatest 2002, 2004, 2006, 2008 ja 2010.

  18. Testing the second demographic transition theory with seemingly unrelated regression: marital postponement and human empowerment / Evgenia Bystrov

    Index Scriptorium Estoniae

    Bystrov, Evgenia

    2014-01-01

    Artikkel keskendub küsimusele, millised on seosed väärtusorientatsiooni ja perekonna käitumise vahel, aluseks maailma väärtusuuringu andmeid aastatest 1981-2008 ning lisaks veel 45 riigi andmed abielude kohta. Esindatud on ka Eesti

  19. Lithologic and physicochemical properties and hydraulics of flow in and near the freshwater/saline-water transition zone, San Antonio segment of the Edwards aquifer, south-central Texas, based on water-level and borehole geophysical log data, 1999-2007

    Science.gov (United States)

    Lambert, Rebecca B.; Hunt, Andrew G.; Stanton, Gregory P.; Nyman, Michael B.

    2010-01-01

    The freshwater zone of the San Antonio segment of the Edwards aquifer in south-central Texas (hereinafter, the Edwards aquifer) is bounded to the south and southeast by a zone of transition from freshwater to saline water (hereinafter, the transition zone). The boundary between the two zones is the freshwater/saline-water interface (hereinafter, the interface), defined as the 1,000-milligrams per liter dissolved solids concentration threshold. This report presents the findings of a study, done by the U.S. Geological Survey in cooperation with the San Antonio Water System, to obtain lithologic properties (rock properties associated with known stratigraphic units) and physicochemical properties (fluid conductivity and temperature) and to analyze the hydraulics of flow in and near the transition zone of the Edwards aquifer on the basis of water-level and borehole geophysical log data collected from 15 monitoring wells in four transects during 1999-2007. No identifiable relation between conductivity values from geophysical logs in monitoring wells in all transects and equivalent freshwater heads in the wells at the times the logs were run is evident; and no identifiable relation between conductivity values and vertical flow in the boreholes concurrent with the times the logs were run is evident. The direction of the lateral equivalent freshwater head gradient and thus the potential lateral flow at the interface in the vicinity of the East Uvalde transect fluctuates between into and out of the freshwater zone, depending on recharge and withdrawals. Whether the prevailing direction on average is into or out of the freshwater zone is not clearly indicated. Equivalent freshwater head data do not indicate a prevailing direction of the lateral gradient at the interface in the vicinity of the Tri-County transect. The prevailing direction on average of the lateral gradient and thus potential lateral flow at the interface in the vicinity of the Kyle transect likely is from the

  20. Hoonete andmed lähevad ehitisregistrisse / Kai Simson

    Index Scriptorium Estoniae

    Simson, Kai

    2003-01-01

    1. jaanuaril 2004 lõpetavad hooneregistri bürood tegevuse ning sealsed säilikud antakse üle rahvusarhiivile. Arhiivi, kus dokument asub, leiab ka ehitisregistri kodulehelt www.ehr.ee. 1. jaan. 2004 saab inimene tutvuda oma andmetega aadressil: www.riik.ee/kodanikuportaal

  1. Eesti Energia unustas Toomas Lumani andmed / Raimo Poom

    Index Scriptorium Estoniae

    Poom, Raimo

    2008-01-01

    Eesti Energia jurist Heili Raudkivi palus rahandusministeeriumilt infot, mis tähtajaks on rahandusminister nimetanud Eesti Energia nõukogu liikmeks Toomas Lumani. Eesti Energia pressiesindaja selgitus

  2. Short Report: Global Infectious Disease Surveillance at DoD Overseas Laboratories, 1999-2007

    Science.gov (United States)

    2010-01-01

    Effective treatment of uncomplicated Plasmodium falciparum malaria with azithromycin- quinine combinations: a randomized, dose-ranging study. Am J Trop...have documented the continued spread of markers suggest- ing the potential for malaria drug resistance emergence- notably recent artesunate-class...Yingyuen K, Sriwichai S, Ohrt C, Knirsch C, 2007. In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation

  3. Identity Issues in Asian-American Children's and Adolescent Literature (1999-2007)

    Science.gov (United States)

    Liu, Yi-chen

    2009-01-01

    Published research suggests that literature should transmit ethnic and societal values as well as reassure one's own confidence and self-respect. This study provides a model for examining Asian-American children's and adolescent literature critically from the perspective of identity issues. It examines fifteen award-winning Asian-American…

  4. Hospitalisation charges for fibromyalgia in the United States, 1999-2007.

    Science.gov (United States)

    Haviland, Mark G; Banta, Jim E; Przekop, Peter

    2012-01-01

    To estimate fibromyalgia (FM) hospitalisation costs (i.e. charges) for patients in the United States from 1999 to 2007; to determine factors associated with variation in costs of FM and non-FM hospitalisations; and to investigate hospital procedures associated with FM hospitalisations. Data were from the Nationwide Inpatient Sample, a large database of hospitalisations in the U.S. Over the study period, an estimated 63,772 patients - two-thirds women, one-third men - had been hospitalised for FM (FM criterion was the International Classification of Diseases, 9th Revision, Clinical Modification diagnosis code 729.1, Myositis and Myalgia, unspecified). Demographics and hospital characteristics were described with frequencies and mean inflation-adjusted charges. Two multivariable linear regressions (one for FM and a second for non-FM patients), with Consumer Price Index (CPI)-adjusted charges (hospital and related services category) in thousands of dollars as the dependent variable, were performed, excluding cases with masked or missing data. Procedures were categorised with a standard classification scheme. Survey-adjusted total CPI-adjusted charges over the study period were estimated to be approximately $1.0 billion. Hospital procedures and Charlson-Deyo Index (co-morbidity severity) scores were the strongest predictors of charges in bivariate and multivariate analyses (for both FM and non-FM patients). The majority of procedures for FM patients were related to musculoskeletal, gastrointestinal, or cardiovascular systems. Most FM patients, however, did not have any procedure or a life-threatening co-morbid illness. Over the nine-year period, hospital charges for FM were substantial. Studies of how to reduce or avoid these costs in the treatment of FM need to be undertaken.

  5. Increasing rates in Clostridium difficile infection (CDI) among hospitalised patients, Spain 1999-2007.

    Science.gov (United States)

    Asensio, A; Vaque-Rafart, J; Calbo-Torrecillas, F; Gestal-Otero, J J; López-Fernández, F; Trilla-Garcia, A; Canton, R

    2008-07-31

    Limited information is available on the burden and epidemiology of Clostridium difficile infection (CDI) in Spain. The present report communicates the secular trends in prevalence of CDI among hospitalised patients in Spain from 1999 through 2007. Data were obtained through the EPINE study (Estudio de prevalencia de las infecciones nosocomiales en los hospitales españoles), a point prevalence study series of nosocomial infections among patients admitted to hospital in Spain. A total of 378 cases with CDI were identified. Median age was 74 years. Prevalence rates of CDI increased from 3.9 to 12.2 cases per 10,000 hospitalised patients and showed a significantly increasing secular trend from 1999 through 2007 (prevalence rate ratio per each year increment 1.09; 95% CI 1.05 - 1.14). Percentage of hospitalised patients receiving antimicrobials increased linearly from 36.0% in 1999 to 40.7% in 2007 (p <0.001) and was strongly correlated to CDI prevalence (R square = 0.73; regression coefficient =1.194, 95% CI= 1.192 - 1.196).

  6. Kala töötlemine : [andmeid aastatest 1995-2004] / Maarja Purik

    Index Scriptorium Estoniae

    Purik, Maarja

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 49-52. Kalatöötlemise osatähtsus toiduainetööstuses moodustas 2004. a. 11,9% ja ekspordis 24,9%. Tabelid. Diagrammid

  7. Management and outcomes following an acute coronary event in patients with chronic heart failure 1999-2007.

    Science.gov (United States)

    Ranasinghe, Isuru; Naoum, Chris; Aliprandi-Costa, Bernadette; Sindone, Andrew P; Steg, P Gabriel; Elliott, John; McGarity, Bruce; Lefkovits, Jeffrey; Brieger, David

    2012-05-01

    The outcome of patients with chronic heart failure (CHF) following an ischaemic event is poorly understood. We evaluated the management and outcomes of CHF patients presenting with an acute coronary syndrome (ACS) and explored changes in outcomes over time. A total of 5556 patients enrolled in the Australia-New Zealand population of the Global Registry of Acute Coronary Events (GRACE) between 1999 and 2007 were included. Patients with CHF (n = 609) were compared with those without CHF (n = 4947). Patients with CHF were on average 10 years older, were more likely to be female, had more co-morbidities and cardiac risk factors, and were more likely to have a prior history of angina, myocardial infarction, and revascularization by coronary artery bypass graft (CABG) when compared with those without CHF. CHF was associated with a substantial increase in in-hospital renal failure [odds ratio (OR) 1.76, 95% confidence interval (CI) 1.15-2.71], readmission post-discharge (OR 1.47, 95% CI 1.17-1.90), and 6-month mortality (OR 2.25, 95% CI 1.55-3.27). Over the 9 year study period, in-hospital and 6 month mortality in those with CHF declined by absolute rates of 7.5% and 14%, respectively. This was temporally associated with an increase in prescription of thienopyridines, beta-blockers, statins, and angiotensin II receptor blockers, increased rates of coronary angiography, and 31.8% absolute increase in referral rates for cardiac rehabilitation. Acute coronary syndrome patients with pre-existing CHF are a very high risk group and carry a disproportionate mortality burden. Encouragingly, there was a marked temporal improvement in outcomes over a 9 year period with an increase in evidence-based treatments and secondary preventative measures.

  8. Rendimiento ex-dividendo como indicador de eficiencia en un mercado emergente:caso colombiano 1999-2007

    OpenAIRE

    Arroyave C., Elizabeth T.; Agudelo R., Diego A.

    2012-01-01

    Se evalúa el rendimiento ex-dividendo en acciones colombianas entre 1999 y 2007, periodo que incluye la conformación en julio de 2001 de la Bolsa de Valores de Colombia, resultado de la integración de tres bolsas previamente existentes. Contrario a la hipótesis de eficiencia de mercado, se encontraron rendimientos exdividendo positivos y estadísticamente significativos, similares a los evidenciados en diversos mercados internacionales. Se comprueba que los rendimientos ex-dividendo no son exp...

  9. História da proibição do skate em Blumenau/SC (1999-2007 = History of the prohibition of skateboarding in Blumenau/SC (1999-2007 = Historia de la prohibición del skate en Blumenau/SC (1999-2007

    Directory of Open Access Journals (Sweden)

    Brandão, Leonardo

    2016-01-01

    Full Text Available Este trabalho se insere num domínio historiográfico conhecido como "História do Esporte". Tomamos como estudo de caso a prática do skate, atividade usualmente inserida no âmbito dos "Esportes Radicais" e que vem sendo praticada por um conjunto significativo de jovens. O recorte geográfico da pesquisa é o município de Blumenau/ SC, geralmente lembrado por ser palco da Oktoberfest. Nesta cidade, a prática do skate foi proibida pela Lei nº 5211, que entrou em vigor no dia 17 de maio de 1999, sendo revogada somente em 2007, durante a gestão do prefeito João Paulo Kleinübing. Para compreender os motivos que levaram o skate a ser proibido, foi realizada uma pesquisa com base em fontes impressas, jornais e revistas, e também através de entrevistas com os principais atores sociais envolvidos com a prática do skate nessa cidade. O objetivo foi analisar tanto os motivos que levaram à proibição dessa atividade em Blumenau quanto seu retorno à legalidade, mapeando a ação dos principais agentes desse processo e também narrando os episódios que envolveram os atos de restrição e coibição à atividade, geralmente efetuados pela guarda municipal. Concluiu-se que, embora a proibição da prática do skate tenha sido decretada em 1999, uma coibição bastante rígida a essa prática já existia desde o final da década de 1980. Além disso, seu retorno à legalidade, ocorrido com a revogação da lei no ano de 2007, foi conquistada através da pressão organizada pelos skatistas, liderada por George Gonçalves, Presidente da União Blumenauense de Esportes Radicais (UBER, e com o apoio da revista 100% skate, uma publicação nacional especializada nessa atividade

  10. Personalihaldusprogramm aitab korrastada töötajate andmed / Heiki Koov

    Index Scriptorium Estoniae

    Koov, Heiki

    2005-01-01

    Personaliarvestuses kasutatava personalihaldusprogrammi (HRM ehk Human Resourse Management) lühike tutvustus. Lisad: Ekraanipilt. Taavi Personali saab sisestada ka töötaja foto; Leia esimese korraga õige programm; Personaliprogrammi lõplik hind sõltub firma spetsiifikast. Vt. samas: Valdo Praust. Personaliprogrammis kasutatavad isikuandmed vajavad hoolikat kaitset

  11. The effects of smoking-related television advertising on smoking and intentions to quit among adults in the United States: 1999-2007.

    Science.gov (United States)

    Emery, Sherry; Kim, Yoonsang; Choi, Young Ku; Szczypka, Glen; Wakefield, Melanie; Chaloupka, Frank J

    2012-04-01

    We investigated whether state-sponsored antitobacco advertisements are associated with reduced adult smoking, and interactions between smoking-related advertising types. We measured mean exposure to smoking-related advertisements with television ratings for the top-75 US media markets from 1999 to 2007. We combined these data with individual-level Current Population Surveys Tobacco Use Supplement data and state tobacco control policy data. Higher exposure to state-sponsored, Legacy, and pharmaceutical advertisements was associated with less smoking; higher exposure to tobacco industry advertisements was associated with more smoking. Higher exposure to state- and Legacy-sponsored advertisements was positively associated with intentions to quit and having made a past-year quit attempt; higher exposure to ads for pharmaceutical cessation aids was negatively associated with having made a quit attempt. There was a significant negative interaction between state- and Legacy-sponsored advertisements. Exposure to state-sponsored advertisements was far below Centers for Disease Control and Prevention-recommended best practices. The significant negative relationships between antismoking advertising and adult smoking provide strong evidence that tobacco-control media campaigns help reduce adult smoking. The significant negative interaction between state- and Legacy-sponsored advertising suggests that the campaigns reinforce one another.

  12. Representação política e de interesses: bases associativas dos deputados federais de 1999-2007

    Directory of Open Access Journals (Sweden)

    Odaci Luiz Coradini

    2011-04-01

    Full Text Available O texto resulta de um trabalho centrado na análise do engajamento associativo no recrutamento e legitimação de elites políticas. Tomando os deputados federais que assumiram no período de 1999 a 2007, são examinadas as diferentes modalidades de relações com sindicatos e associações. Essas relações são confrontadas com outras condições e recursos presentes nos respectivos trajetos, tais como aqueles ligados à titulação escolar, ao montante do patrimônio econômico, à filiação partidária e à quantidade de mudanças de partido político. Conforme uma das conclusões gerais, ocorre uma forte homologia entre a distribuição dos deputados conforme suas vinculações associativas, na política partidária e no espaço político. Porém, não se trata apenas de alguma dicotomia entre esferas de atividades, associativas e político-partidárias, mas de diferentes padrões de complementaridade, afinidades eletivas, ambivalências e de distanciamento e, portanto, de recursos e modalidades que podem ser utilizadas em diferentes condições e processos de politização.This paper results from an analysis of the associative engagement for the recruitment and legitimization of political elites. The different modalities of the relations with unions and associations are examined considering the federal deputies who have taken their positions from 1999 to 2007. These relations are compared to other conditions and resources such as those related to schooling degree, the amount of economical property, partisan affiliation and the number of switching between political parties. According to one of the general conclusions, there is a strong homology between the distribution of federal deputies according to their associative relation, both in partisan politics and in the political environment. However, this is not simply a dichotomy between activities, associative and political-partisan scopes, but rather different patterns of complementarity, elective affinities, ambivalences and detachment, and therefore different patterns of resources and modalities that could be used in different conditions and processes for politization.

  13. Fondos de inversión éticos, ecológicos y socialmente responsables en Europa (1999-2007

    Directory of Open Access Journals (Sweden)

    Luis Ferruz Agudo

    2009-04-01

    Full Text Available El principal objetivo de este trabajo es reflexionar sobre la evolución que ha experimentado en los últimos años la industria de los fondos de inversión socialmente responsables en Europa. Para ello analizamos la evolución del número de fondos éticos ofertados, el crecimiento de su patrimonio, su tamaño, la tipología de fondos comercializados y las principales empresas que componen sus carteras de inversión, mostrando la importancia que están cobrando en Europa los fondos de inversión socialmente responsables en los primeros años del siglo XXI.

  14. Kaks luustikku Tartu toomkirikust: arheoloogia ja osteoloogia andmed / Two skeletons from the Tartu Cathedral Cemetery: archaeological and osteological data

    Directory of Open Access Journals (Sweden)

    Martin Malve

    2011-01-01

    Full Text Available This article deals with two case studies based on the osteological obtained in the rescue excavations in the Cathedral of Tartu in 2001 and 2008 (fig. 1. The first case study focuses on the skeleton of the child who suffered from congenital syphilis. The grave has been dated to the end of the 17th or the beginning of the 18th century. The child had been buried in the eighth nave of the northern aisle of the Cathedral (fig. 3. The grave was, according to the Christian burial traditions, west-oriented with the head facing towards the east. A Swedish 1/6 öre, minted during the reign of King Charles XI (1600–1697, was recovered from the grave. The skeleton was relatively complete and well preserved (fig. 2. Based on the dental eruption, the age at death was 9 years ± 24 months. Sexually distinctive characteristics had not developed, and thus it was impossible to determine the sex of the child. Both the microscopical and radiological analyses revealed that the skeleton had indicators of congenital syphilis. Damage from gummatous osteomyelitis and periostitis were visible on the skull and on the axial and appendicular skeleton (fig. 6, while Hutchinson’s incisors and Mulberry molars were present among the teeth. Deformations and damage on the bones suggest that the child had suffered from the disease for quite a long time.The second case study discusses a beheaded man found from the eighth nave in the southern aisle of the Cathedral (fig. 3. The grave pit had a depth of 80 cm from the medieval floor surface of the church, which indicates that the burial dates from the Middle Ages. Also, the head of the deceased pointed to the west.The bones were well preserved (fig. 6. Sex was determined from the characteristics of the skull and the length of the right humerus. Calcification of the cranial sutures and cartilages suggests that the age of the man at death was probably 50+. Macroscopic examination of the skeleton revealed that the man had suffered from slight forms of various spinal diseases, which include Schmorl’s nodes, spondyloarthrosis, and spondylosis. The fourth and fifth cervical vertebrae had ankylosis, the cause of which is unknown. Signs of osteoartrosis, a joint disease, were also noticed. Traumas recorded in the skeleton include a healed fracture of a rib and vertebral compression. The man’s head was decapitated with a sharp blade between the sixth and seventh cervical vertebrae (fig. 7.

  15. Effect of different levels of protein concentrates supplementation on the growth performance, plasma amino acids profile andmTORcascade genes expression in early-weaned yak calves.

    Science.gov (United States)

    Peng, Q H; Khan, N A; Xue, B; Yan, T H; Wang, Z S

    2018-02-01

    This study evaluated the effects of different levels of protein concentrate supplementation on the growth performance of yak calves, and correlated the growth rate to changes occurring in the plasma- amino acids, -insulin profile, and signaling activity of mammalian target of rapamycin ( mTOR ) cascade to characterize the mechanism through which the protein synthesis can be improved in early weaned yaks. For this study, 48 early (3 months old) weaned yak calves were selected, and assigned into four dietary treatments according to randomized complete block design. The four blocks were balanced for body weight and sex. The yaks were either grazed on natural pasture (control diet) in a single herd or the grazing yaks was supplemented with one of the three protein rich supplements containing low (17%; LP), medium (19%; MP), or high (21%; HP) levels of crude proteins for a period of 30 days. Results showed that the average daily gain of calves increased (0.14 vs 0.23-0.26 kg; pprotein concentrates supplementation. The concentration of plasma methionine increased (p0.05) when the grazing calves were supplemented with protein concentrates. Compared to control diet, the insulin level of calves increased (psupplementation of protein concentrates. Addition of protein concentrates up-regulated (pprotein sorting 34 homolog, the translational regulators eukaryotic translation initiation factor 4E binding protein 1, and S6 kinase 1 genes in both Longissimus dorsi and semitendinosus. In contrast, the expression of sequestosome 1 was down-regulated in the concentrate supplemented calves. Our results show that protein supplementation improves the growth performance of early weaned yak calves, and that plasma methionine and insulin concentrations were the key mediator for gene expression and protein deposition in the muscles.

  16. Eesti Vabariigi rahvusvahelised mitmepoolsed lepingud aastatest 1918-1940: ühinemine ja kehtivus : [bakalaureusetöö] / Vivian Loonela ; Tartu Ülikool, õigusteaduskond ; juhendaja: Aino Lepik von Wirén

    Index Scriptorium Estoniae

    Loonela, Vivian

    1999-01-01

    Eesti Vabariigi riikluse areng, rahvusvaheliste mitmepoolsete lepingute kehtestamismenetlus, EV ühinemine rahvusvaheliste mitmepoolsete lepingutega Riigikogus, EV järjepidevus, lepingute staatus käesoleval hetkel

  17. Soome-ugri rahvaste proosa jõudis eesti lugejate ette / Nikolai Kuznetsov, Vasli Nikolajev, Muš Nadii ; intervjueerinud Üve Maloverjan

    Index Scriptorium Estoniae

    Kuznetsov, Nikolai

    2013-01-01

    Autorid tutvustavad proosakogumikke: Vana maja monoloog : valik mari proosat : 26 lugu 23-lt autorilt aastatest 1927–2010. Tallinn, 2012 ; Seal kaugel-kaugel : valik komi proosat : 30 lugu 27-lt autorilt aastatest 1924-2010. Tallinn, 2011 ; Varsti on jälle kevad : valik udmurdi proosat : 39 lugu 34-lt autorilt aastatest 1890-2010. Tallinn, 2012

  18. Social consequences of transition : who recognize themselves to be poor in Estonia? / Tiiu Paas, Andres Võrk

    Index Scriptorium Estoniae

    Paas, Tiiu, 1949-

    2003-01-01

    Analüüs, kuidas on omavahel seotud leibkonna sissetulekuga määratud vaesus ja inimeste enda poolt antud hinnang oma majanduslikule olukorrale. Kasutatud on ESA Leibkonna Eelarve Uuringu andmeid aastatest 2000 ja 2001. Tabelid

  19. Kultuuriajakirjad sotsioloogi pilguga / Marju Lauristin

    Index Scriptorium Estoniae

    Lauristin, Marju, 1940-

    2008-01-01

    Vaadeldakse "Keele ja Kirjanduse" ning teiste kultuuriajakirjade lugejate arvu muutumist 1950. aastatest kuni tänapäevani, ning mõtiskletakse lugejaskonna suurendamise võimalikkuse ja/või vajalikkuse üle

  20. Plaat

    Index Scriptorium Estoniae

    2006-01-01

    Heliplaadid kauplustest Lasering: Beck "The Information", Enigma "A Posteriori", Kosmikud "Pulmad ja matused", And One "Bodypop", Uno Loop "Viimane suudlus - duetid aastatest 1964-1979", Motörhead "Kiss Of Death"

  1. Ilmar Arens : 29. XI 1912 - 9. I 1994 / Vello Helk

    Index Scriptorium Estoniae

    Helk, Vello, 1923-2014

    2001-01-01

    Astus Tartu Ülikooli õigusteaduskonda 1935 aastal. 1946. aastal promoveeriti õigusteaduste doktoriks. Artiklis viidatud ka I. Arensi erinevatele artiklitele ja uurimustele. Lisatud foto. Ilmar Arensi tööde bibliograafia aastatest 1991-1999 lk. 371

  2. Estonian economic growth slows down / Olavi Grünvald

    Index Scriptorium Estoniae

    Grünvald, Olavi

    2008-01-01

    Ülevaade Eesti majandusliku arengu viimastest aastatest, 2007. aastal alanud majanduslangusest, mida iseloomustavad langus kinnisvaraturul, SKT kasvu aeglustumine, transiitkaubanduse vähenemine. Lisatud tabel diagramm ja graafikud

  3. Contra pürib sajandi rahvakirjanikuks / Aivar Kull

    Index Scriptorium Estoniae

    Kull, Aivar, 1955-

    2001-01-01

    Contra [Konnula, Margus]. Suusamütsi tutt : luulet aastatest 1974-2000. Urvaste ; Tartu : Mina Ise, 2001. Vaata ka: Kull, Aivar. Kulli pilk. - Tartu : Ilmamaa, 2005, lk. 184-185, pealkirjaga "Contra - uue sajandi rahvakirjanik?"

  4. Auraalne Contra / Hasso Krull

    Index Scriptorium Estoniae

    Krull, Hasso, 1964-

    2001-01-01

    Bibliogr. joonealustes märkustes. Rets. rmt. : Contra [Konnula, Margus]. Suusamütsi tutt : luulet aastatest 1974-2000. Urvaste ; Tartu : Mina Ise, 2001; Contra [Konnula, Margus]. Contra on õhk : [helikassett]. Urvaste :¡ Mina Ise, 2000

  5. Teaduste tempel / Guntars Graiksts

    Index Scriptorium Estoniae

    Graiksts, Guntars

    2004-01-01

    Riia arhitektuurist. Kolhoosnike Maja, hilisema Läti Teaduste Akadeemia maja kavandamise ja ehitamise lugu alates 1950. aastatest. Kõrghoone valmis 1961. a. Arhitektid Osvald Tilmanis, Nikolai Akmenis, Edvard Ekabson ja Vaidelotis Apsitis (siseviimistlus)

  6. Tsena, ravnaja zhizni / Leonid Stolovitsh

    Index Scriptorium Estoniae

    Stolovitš, Leonid, 1929-2013

    2003-01-01

    Saksa arhitektuuriteoreetikust ja graafikust Kurt Magritzist ja tema fashismivastase sisuga graafikast ja joonistustest aastatest 1933-1945. 1966. a. mais oli K. Magritzi graafika näitus Tartu Kunstimuuseumis

  7. Estonian Society and Political Pictures : 6 Case Studies / Peeter Linnap

    Index Scriptorium Estoniae

    Linnap, Peeter, 1960-

    2002-01-01

    Kuus lugu Eesti dokumentaal- ja poliitilisest fotograafiast - põgenemine Läände, eestlased Teises maailmasõjas, Jüri Liimi fotod 1990. aastatest, Carl Sarapi ja Peeter Toominga fotolood, Marko Laimre "Jaotatud territooriumid"

  8. Uus võib olla unustatud vana / Raivo Juurak

    Index Scriptorium Estoniae

    Juurak, Raivo, 1949-

    2009-01-01

    Vestlusest kooliajaloolase Ilmar Kopsoga, kes töötas läbi ja pani haridusministeeriumi tellimusel Internetti Eesti hariduskorralduse aktid aastatest 1918-1940. Nendega saab tutvuda aadressil: http://www.hm.ee/Haridusseadused-1918-1940/

  9. Plaadid / Brigitta Davidjants

    Index Scriptorium Estoniae

    Davidjants, Brigitta, 1983-

    2006-01-01

    Uutest heliplaatidest Arabanda "Shams", Uno Loop "Viimane suudlus: Duetid aastatest 1964-1979", Mister Bond "A Jazzy Coctail Of Ice Cold Themes", Damien Rice "9", Kulo "Dysenteria", Bad Apples "When Colours Become Day And Night", Akon "Konvicted"

  10. 1930. aastad Kaukaasias "Edasi" kolhoosis põllumehe silme läbi ja ajalehe "Edasi" veergudel. IV-V / Marika Mikkor

    Index Scriptorium Estoniae

    Mikkor, Marika, 1963-

    2006-01-01

    Kaukaasias Eesti-Rohuaias elanud August Rootsi päevaraamatust 1929-1942 aastatest ja Leningradis ilmunud ajalehe "Edasi" kirjutistest stalinlike repressioonide, kollektiviseerimise ja eestlaste eluolu kohta Kaukaasias

  11. Sangaste loss / Otto Pius Hippius

    Index Scriptorium Estoniae

    Hippius, Otto Pius, 1826-1883

    1996-01-01

    esmakordselt mainitud 13. saj. Sangaste mõisa omanik Berg, Friedrich Wilhelm (1794-1874). Lossi interjöörid, fotod 1920-ndatest aastatest, lossi välisvaade, foto 1920-ndatest aastatest, lk. 335. Loss, vaade esifassaadile, värv., lk. 336-337, Vaade lossile üle tiigi metsapargist, värv., lk. 338. Ballisaal, salong, värv.

  12. Eestlased sisustamas maailma suurimat laeva / Oliver Rand

    Index Scriptorium Estoniae

    Rand, Oliver, 1971-

    2000-01-01

    Soome laevaehitusfirma Kvaerner Masa-Yards kaasas Eesti sisustusfirma Lindal Private laevaehitusprojekti, mille tulemusel valmivad viie aasta jooksul kolm maailma suurimat luksusreisilaeva. Tabel: Maailma suurima reisilaeva tehnilised andmed

  13. Social protection and satisfaction with democracy: a multi-level analysis / Kadri Lühiste

    Index Scriptorium Estoniae

    Lühiste, Kadri

    2014-01-01

    Artiklis analüüsitakse sotsiaalkaitse kvaliteedi seoseid kodanike rahuloluga demokraatia funktsioneerimisega, aluseks 24 riigi Euroopa sotsiaaluuringu andmed 2008. aastast, meetodina kasutatakse regressioonanalüüsi

  14. Tüdimus ; Levant ; Agoonia ; Varjutus ; Mälestuseks ; Jõed ; Jõulud ; Kui sina mu vend ; Faas ; Maetud sadam ; Õhtul ; Needus ; Juuni ; Magada ; Rahu : [luuletused] / Giuseppe Ungaretti ; tõlk. Malle Talvet ja Auli Ott

    Index Scriptorium Estoniae

    Ungaretti, Giuseppe

    2003-01-01

    Andmed autori kohta lk. 28. Orig.: Noia ; Levante ; Agonia ; Chiaroscuro ; In memoria ; I fiumi ; Natale ; Se tu mio fratello ; Fase ; Il porto sepolto ; Stasera ; Dannazione ; Giugno ; Dormire ; Quiete

  15. The perfect match? A closer look at the relationship between EU consumer law and data protection law / Natali Helberger, Frederik Zuiderveen Borgesius, Agustin Reyna

    Index Scriptorium Estoniae

    Helberger, Natali

    2017-01-01

    Andme- ja tarbijakaitse regulatsioonide vastastikusest mõjust kaitse regulatsiooni mõjust tarbijakaitses ja vastupidi (nt tarbijate teavitamine nn tasuta teenustest ja ebaõiglastest tingimustest tarbijalepingutes)

  16. Eestlastest teenistujad BÜ-s ja UNRRA-s, IRO-s

    Index Scriptorium Estoniae

    1991-01-01

    Teadaolevad andmed kaheksa töötaja kohta. UNRRA = ÜRO Abistamis- ja Taastamisadministratsioon (United Nations Relief and Rehabilitation Administration); IRO = Rahvusvaheline Põgenikeorganisatsioon (International Refugee Organization )

  17. Mida on oodata majanduslanguse ootajatel / James C Cooper

    Index Scriptorium Estoniae

    Cooper, James C

    2008-01-01

    USA majanduse prognoosimiseks tuleb autori sõnul jälgida nelja majandusnäitajat: iganeljapäevased andmed uute töötuskindlustushüvitise taotluste kohta, ostujuhtide assotsiatsiooni Institute of Supply Management tootmis- ja mittetootmissektori aktiivsusindeksid ning USA tööministeeriumi tööhõivearuanne. Tabel: Praegused andmed võrreldes varasemate majanduslangustega

  18. EL turud avanevad / Säde Kelder

    Index Scriptorium Estoniae

    Kelder, Säde

    2004-01-01

    Autor analüüsib Eesti toidukaupade väliskaubandusstatistikat aastatest 2000-2002. Diagrammid: Põllumajandussaaduste eksport aastatel 2000-2002; Põllumajandussaaduste eksport ilma tolliladudeta ja import vabaks ringluseks Eestis aastatel 1994-2002; Põllumajandussaaduste import aastatel 2000-2002

  19. Mir̤ näitus Stockholmis

    Index Scriptorium Estoniae

    1998-01-01

    Hispaania kunstniku Joan Mir̤ looming koos sürrealistide töödega 30. augustini Stockholmi vastavatud Moodsa Kunsti Muuseumis (arhitekt Rafael Moneo). Eksponeeritud 150 Mir̤ teost alates 1919. aastast, kõige rohkem on väljas maale 1920-1950. aastatest

  20. Richard Avedon ja Annie Leibovitz laulsid kaanonit / Marika Alver

    Index Scriptorium Estoniae

    Alver, Marika

    2008-01-01

    Richard Avedoni (1923-2004) retrospektiivnäitusest (fotod aastatest 1946-2004) kuraator Helle Crenzien (Lousiana Kaasaegse Kunsti muuseum Taanis), millega kaasnes ka Helen Whitney film "Richard Avedon : darkness and light" ja Annie Leibovitzi (1949) suurprojektist "A photographer's life 1990-2005" Pariisis

  1. November on Eestis prantsuse kultuuri kuu

    Index Scriptorium Estoniae

    2012-01-01

    Prantsuse Instituut korraldab novembris erinevate kunstivaldkondade ürituste sarja "Accord", mille raames on Tallinna Ülikooli Mare maja aatriumis avatud prantsuse fotograafi ja režissööri Raphaël Gianelli-Meriano näitus "Minu Eesti suved, fotod aastatest 2002-2012"

  2. Kuldsõduri ja ufo invasioon / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2010-01-01

    Kristina Normani isikunäitus "Me ei ole universumis üksi" Tallinna Kunstihoones 10. aprillist 9. maini 2010. Näitus hõlmab kunstniku loomingut aastatest 2007 - 2010. Installatsioonist "After-War" ja kunstiteosest, mille aluseks on ufomälestusmärk Padisel Pae külas Poosimatsi talus

  3. Keila-Joa loss / Theodor Gehlhaar

    Index Scriptorium Estoniae

    Gehlhaar, Theodor, 1805-1871

    1996-01-01

    Lossiansambel, fragment 19. saj. keskpaiga kaardilt; lk. 328-329 (loss, Th. Gehlhaari akvatinta, 1832-1833. a.) värv.; lk. 330 (lossiansambel, Th. Gehlhaari akvatinta, 19. saj. II veerand), värv.; lk. 331 (lossiansambel, postkaart 1910. aastatest), värv.

  4. The oldest Danish ballad tradition in its socio-cultural setting / Hanne Ruus

    Index Scriptorium Estoniae

    Ruus, Hanne

    2003-01-01

    Artikkel põhineb 1993-1998 a. läbi viidud põhjalikul uurimistööl, milles uuriti taani ballaadide ja laulude käsikirju aastatest 1550-1700 ning ka nende omanikke ja kollektsionääre sotsiaalkultuurilises kontekstis

  5. Tippkunstnike müügiedu Tallinnas / Georg Poslawski

    Index Scriptorium Estoniae

    Poslawski, Georg

    1998-01-01

    Müüginäitustest. 3.-21. märtsini Vaal-galeriis Antoni T̉piesi graafikakollektsioon aastatest 1973-1994. 5. märtsil pakkus Deco galerii Tallinna WTCs Salvador Dali graafikat - üheksat litograafiat sarjast "Lilled". Kunstnikest, nende loomingust. Hindadest.

  6. Nõukogudemaa underground bootleg'id / Margus Paju

    Index Scriptorium Estoniae

    Paju, Margus

    2008-01-01

    DVDst "Päratrusti pärand" - ENSV Riikliku Kultuurijäätmete Töötlemise Artelli "Päratrust" kultusfilmide kogumikust. Mustvalged underground-lühimängufilmid "Tsarli läheb Tallinna", "Tsaar Muhha", "Neurootiline pärastlõuna", "Kalkar", "Päratee" jt. aastatest 1980 -1983, filmid on taashelindatud 2007. aastal

  7. Keldrisse elama! / Elli Noorik

    Index Scriptorium Estoniae

    Noorik, Elli

    2007-01-01

    Keldriruumi ümberkujundamisest magamistoaks. Näidetena Tallinnas Roopa tänava 1903. a. ehitatud (ehitus- ja renoveerimistöid tegi OÜ Vana-Asum) ja Asula tänava 1960. aastatest pärit kortermaja.8 värv. ill.

  8. Põhiseaduse riigikontrolli-peatüki teksti areng Põhiseaduse Assamblee menetluses : [bakalaureusetöö] / Toomas Mattson ; Akadeemia Nord, õigusteaduskond ; juhendaja: Igor Gräzin

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2008-01-01

    Põhiseaduse kavad aastatest 1989-1990 (Gräzini eelnõu, Talviku-Kaljuvee eelnõu), viie eelnõu võrdlus 1938. a. põhiseadusega (Raidla, Lepsi, Adamsi, Kulboki eelnõud), Põhiseaduse Assamblee istungitest - kolm lugemist ja neljas faas, menetluse käigus tehtud olulisemad muudatused

  9. Vid na himkombinat v Maardu so stenõ Hudozhestvennoi galerei / A. Orshanskaja

    Index Scriptorium Estoniae

    Orshanskaja, A.

    1999-01-01

    Eesti akvarellistide ühingu vabariiklikust näitusest Narva kunstigaleriis : akvarelle aastatest 1960 - 1999 eri põlvkondade 43 kunstnikult. Esinevad ka 6 Narva kunstnikku : Igor Gordin, Vera Lantsova, Anne Pärtel, Jelena Sabinina, Tatjana Sonina, Irina Sopina.

  10. Tagasisidet peab töötajale vahendama ülemus / Mait Raava

    Index Scriptorium Estoniae

    Raava, Mait

    2004-01-01

    Autor teeb lühiülevaate 360ʻ ja teiste tagasiside meetodite rakendamisest maailmas alates 1950ndatest aastatest ning juhib tähelepanu vigadele, mida meetodi rakendamisel on tehtud. Kommenteerib Irene Metsis. Skeem: Juht saab tagasiside nelja kanali kaudu. Vt. samas: Rollist tulenevalt on tagasiside erinev

  11. Kadunud linna otsinguil / Richard Woods

    Index Scriptorium Estoniae

    Woods, Richard

    2000-01-01

    University of East Londoni arheoloogiatudeng Alan Robinson leidis 1998. a. Mehhiko dzhunglist umbes aastatest 600-900 pKr pärineva linna, mis katab 12 ruutmiili suuruse ala. Seni on leitud 11 väljakut, 10 püramiidikujulist ehitist, 6 ümmargust ehitist, 11 sammast.

  12. Pop-art s britanskim aktsentom / Aleksandra Manukjan

    Index Scriptorium Estoniae

    Manukjan, Aleksandra

    2003-01-01

    Rotermanni soolalaos avatakse briti popkunsti näitus AS IS WHEN. Näha graafikat aastatest 1961-1972 kahekümnelt briti kunstnikult. Nimed loetletud, esile toodud Ricard Hamilton, David Hockney, Allen Jones. Korraldab Briti Nõukogu, kuraator Richard Riley

  13. Isepäine üldküsilause / Helle Metslang

    Index Scriptorium Estoniae

    Metslang, Helle, 1950-

    2010-01-01

    Vaadeldakse kahe üldküsilausetüübi (partikli või küsijätkuga vormistatud lause või sõnajärje, rõhu, intonatsiooni erinevusega vormistatud lause) vahekorda ja dünaamikat eesti kirjakeeles alates 1890. aastatest ja levikut tänapäeval eri registrites

  14. Uus mälu : Eesti Vabariigi muuseumipoliitika 1919-1924 / Mariann Raisma

    Index Scriptorium Estoniae

    Raisma, Mariann, 1974-

    2011-01-01

    Noore Eesti Vabariigi vajadusest uute mäluasutuste järele. Haridusministeeriumi muinsusosakonnast ja selle tööst eesotsas Kristjan Rauaga. Vabadussõja muuseumi loomisest. Eesti Rahva Muuseumist. Tallinna Eesti Muuseumi esimestest aastatest. Muuseumide riigistamise ja Eesti Kunstimuuseumi küsimusest. Vabaõhumuuseumi ideest

  15. Õunad, naljad ja Stalin : Maarja mälestused Viivi maagilisest maailmast / Maarja Talgre

    Index Scriptorium Estoniae

    Talgre, Maarja, 1945-

    2007-01-01

    Maarja Talgre isiklikest mälestustest seoses Viivi Luigega, Viivi Luige romaanidest "Ajaloo ilu" (Tallinn : Eesti Raamat, 1991) ja "Seitsmes rahukevad" (Tallinn : Eesti Raamat, 1985) ning kuuldemängust "Koera sünnipäev" (ilmunud kogumikus "Kas kuulete... ? : valimik raadionäidendeid aastatest 1994-2000" / koosatnud Tamur Tohver. Tallinn : Kirjastuskeskus, 2002)

  16. Korp! Rotalia Los Angeleses / Bruno Laan, Jüri Tint

    Index Scriptorium Estoniae

    Laan, Bruno, 1926-

    1988-01-01

    Sisaldab ka nimekirja rotalustest ja nende perekonnaliikmetest XIV Lääneranniku Eesti Päevade juhtkonnas, Los Angelese konvendi presiidiumite nimekirja aastatest 1957-1986, Los Angelese konvendi magistrite ja ametmeeste nimekirja 1960-1986 ja konvendis peetud referaatide nimekirja 1959-1985

  17. Lasteaed = Day-care / Mart Kalm

    Index Scriptorium Estoniae

    Kalm, Mart, 1961-

    2013-01-01

    Lasteaedade ehitus Eestis algas 1920-ndatel aastatel. 1950-ndatest aastatest alates hakati lasteaedu ehitama tüüpprojektide järgi. Leidub ka üksikuid lasteaedu, mis pidid selle ehitanud ettevõtte jõukust ja hoolt demonstreerima

  18. Siserände suundumused 20. sajandil = Trends of internal migration during the 20th century and at the beginning of the 21st century / Alis Tammur

    Index Scriptorium Estoniae

    Tammur, Alis

    2008-01-01

    Siserände suundadest Eestis alates 1920ndatest aastatest kuni 2007. aastani. Kaart: Linnadesse tulnud endise alalise elukoha järgi, 1922-1934. Graafik: Siserände vanusjaotus. Tabel: Linnade ja maa-asulate vahelised rändesuunad 2000-2007

  19. Participation, equality of opportunity and returns to tertiary education in contemporary Europe / Fabrizio Bernardi, Gabriele Ballarino

    Index Scriptorium Estoniae

    Bernardi, Fabrizio

    2014-01-01

    Artiklis käsitletakse kõrghariduspoliitikat Euroopas, täpsemalt võrdsete haridusvõimaluste edendamist ning tööjõu pakkumise ja nõudluse arendamist, aluseks 2005. aasta EU-SILC ja 23 riigi (sh Eesti) Euroopa sotsiaaluuringu andmeid aastatest 2002-2010

  20. Minevikutõlgenduste ja ajakäsituste uurimine pärimusliku ajaloo vaatepunktist : kahe temaatilise jutustuse näitel / Tiiu Jaago

    Index Scriptorium Estoniae

    Jaago, Tiiu, 1960-

    2004-01-01

    Virumaa tööstusala arengut käsitlevast kahest kirjalikust jutustusest aastatest 1961 ja 2001. Artiklis analüüsitakse sündmuste ja jutustamise aja omavahelisi seoseid ning ajastu tõlgendamist mõjutavaid tegureid

  1. Kui too suvi poleks olnud nii vihmane / Theodore K. Rabb

    Index Scriptorium Estoniae

    Rabb, Theodore K.

    2003-01-01

    1520. aastatest, mil olid rängad ilmastiku tingimused, mis takistasid Osmanite sultani Süleyman Toreda sissetungi Euroopasse. Samal teemal : Pierson, Peter. Kui püha liiga poleks kõikuma löönud, lk. 128

  2. Sotsialistlik realism Eestis

    Index Scriptorium Estoniae

    2002-01-01

    Tartu Kunstimuuseumis näitus "Sotsialistliku realismi võidukäik? Eestis". Kuraator Reet Mark. Vaadata saab aastatel 1948-56 Moskvast ja Leningradist Eestisse saadetud "näidiskunsti" ja sotsialistlikku realismi eesti autoritelt aastatest 1940-1956. 11. X ettekannete päeval esinejaid

  3. 600 filmi kenas ruskes Soome linnas / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    2005-01-01

    Tampere 35. lühifilmide festivalil nähtust. Näidati ka täissaalile 12 Riho Undi ja Hardi Volmeri animafilmi aastatest 1986-2000. Grand prix "Suur Suudlus" läks vene päritolu Norra animaatorile filmi eest "Läbi mu paksude prillide" ("Gjennom mine tykke briller")

  4. M.O.O.D. / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    1999-01-01

    Rotermanni soolalaos ja Viru tänava vaateakendel sajandi lõpu suurprojekt M.O.O.D., mis käsitleb Eesti moefenomeni aja ja kunsti mõjusfääris 1920. aastatest tänapäevani. Kuraator Liivia Leshkin.

  5. Kevadtiivul Eestisse / Heli Silma

    Index Scriptorium Estoniae

    Silma, Heli

    2000-01-01

    Kathleen Caillier'i (s. 1967) näitus "Kevadtiivul" La Galerie Passage'is. Eksponeeritud õrnades toonides lillemaalid, natüürmordid ja maastikud aastatest 1994-2000. Kunstnik on täiendanud töid luuleridadega.

  6. Kirjavahetus, millest sündis kirjanik / Eerik Purje ; fotod: Eerik Purje

    Index Scriptorium Estoniae

    Purje, Eerik, 1927-

    2010-01-01

    6. mai õhtul toimus Tartu College’i meeskorporatsioonide ruumis Piret Noorhani loeng, milles lektor käsitas peaasjalikult Ella Ilbaku ja August Gailiti kirjavahetust aastatest 1952 - 1961. Selle kirjavahetuse on ta ka avaldanud raamatuna möödunud aastal

  7. Kolme kirjaniku jumalikud ilmutused / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2008-01-01

    Arvustus: Rooste, Jürgen. Tavaline eesti idioot ja teisi pikemaid poeese 1999-2007; Chaneldior. Kontrolli alt väljas : [jutustused] ; Andreas W., pseud. Gatlingi kuulipilduja : esseed (Pärnu : [Jumalikud Ilmutused], 2008)

  8. Surgical conditions and requested procedures for ruminants and ...

    African Journals Online (AJOL)

    Surgical conditions and requested procedures for ruminants and small animals handled at the College of Veterinary Medicine and Agriculture clinic, Debre Zeit, Ethiopia: A retrospective study 1999-2007.

  9. Aasta 1998 : Põhjamaalased eirasid loodusseadusi... ka kindlustuses / River Tomera

    Index Scriptorium Estoniae

    Tomera, River

    1999-01-01

    Ülevaade Eesti kindlustusturust 1998.a. Sundkindlustuse turg, ettevõtete turg, eraisikute turg, õnnetusjuhtumi- ja reisikindlustus, elukindlustuse turg (1997. ja 1998.a. andmed: juurdekasv, segmendi osa turul). 1998.a.

  10. Hispaania kurk, made in Poland / Gunnel Koba

    Index Scriptorium Estoniae

    Koba, Gunnel

    2009-01-01

    Taimekaitse vahendite kahjulikust mõjust inimese tervisele ning Veterinaar- ja toiduameti andmed Eestis aastail 1998-2007 uuritud puu-, juur- ning aedviljade taimekaitsevahendite ja pestitsiidijääkide seire proovidest

  11. Talv venib edasi ; Aspasia ; "Kohtumine..." ; Dora Markus ; "Hakkad rääkima minust sellesama..." ; "Iidne meri, olen joobubud häälest..." ; "Selles punktis peatu..." ; Väike testament : [luuletused] / Eugenio Montale ; tõlk. Lauri Pilter

    Index Scriptorium Estoniae

    Montale, Eugenio

    2003-01-01

    Andmed autori kohta lk. 28. Orig.: L'inverno si prolunga, il sole adopera ; Aspasia ; Incontro ; Dora Markus ; Parlerai di me con lo stesso ; Antico, sono ubriacato dalla voce ; A questo punto ; Piccolo testamento

  12. Kogu elu tööliste keskel / Aarne Ruben

    Index Scriptorium Estoniae

    Ruben, Aarne, 1971-

    2003-01-01

    Portreefilm filmimees Semjon Shkolnikovist "Igaviku seisukohalt" : stsenarist Igor Ruus : režissöörid Igor Ruus ja Heli Speek : produtsent Igor Ruus : Estonia Film 2002. Lisatud andmed Igor Ruusi, Heli Speegi ja Aarne Rubeni kohta, lk. 114

  13. Doroga do jevroporoga / Mihhail Tuzhikov

    Index Scriptorium Estoniae

    Tuzhikov, Mihhail

    2003-01-01

    Ülevaade investeeringutest maanteede remonti Eestis, Lätis, Leedus, samuti projektidest Via Baltica ja Via-Hanseatica. Tabel: Võrdlevad andmed Baltimaade ja Soome teedest. Diagrammid: Investeeringute jagunemine Baltimaades projektis Via Baltica 1996-2006

  14. Pila paatose asemel / Mari Laaniste

    Index Scriptorium Estoniae

    Laaniste, Mari, 1977-

    2007-01-01

    Dokumentaalfilm animaator Priit Pärnast "Mees animatsioonist" : režissöör Hardi Volmer : peaprodutsent ja operaator Arko Okk : stsenarist Toomas Kall : helilooja Olav Ehala : Acuba Film 2005. Lisatud andmed H. Volmeri kohta

  15. Naqoyqatsi / Todd McCarthy ; tõlk. Kristiina Davidjants

    Index Scriptorium Estoniae

    McCarthy, Todd

    2003-01-01

    PÖFFil näidatavaid filme - USA dokumentaalfilm 2002. aastast "Naqoyqatsi", mille stsenarist ja režissöör on Godfrey Reggio, muusika autor Philip Glass. Lisatud andmed Godfrey Reggio kohta, lk. 103

  16. Super Cyber Villains / Marge Tubalkain-Trell

    Index Scriptorium Estoniae

    Tubalkain-Trell, Marge

    2008-01-01

    Rahvusvaheline kurjategijate grupp varastas 40 miljoni krediitkaardi andmed. Küberrünnakud on saanud strateegiliseks relvaks väikeriikide ründamisel, Venemaa on juba rünnanud Eestit, Gruusiat ja Leedut

  17. Algas esimese tankeri ehitus Eestis

    Index Scriptorium Estoniae

    2005-01-01

    Eesti laevaremondi ja masinaehitusettevõte SRC Uusehitused OÜ alustas Eestis esimese tankeri ehitust. Ettevõte on peatöövõtja kuue tankeri ehitamisel, mille tellijaks on Rootsi firma Svythoid Tankers. Lisa: Andmed ehitatava tankeri kohta

  18. Draakon teritab küüniseid / Kaarel Kaas

    Index Scriptorium Estoniae

    Kaas, Kaarel, 1978-

    2005-01-01

    Hiina-USA viimaste aastakümnete tõsisem konflikt, mis sai alguse Hainani intsidendist. Hiina suhtes 1989. a. kehtestatud relvaemargo kaotamisest. USA julgeoleku- ja Euroopa Liidu majandushuvid. Tabel: Hiina sõjaliste kulutuste ametlikud andmed

  19. Maailmarändur kiirustab vabas graafikus / Kerttu Jänese

    Index Scriptorium Estoniae

    Jänese, Kerttu, 1981-

    2007-01-01

    Maailmafilmi programmikoordinaator, etnoloog ja filmirežissöör Liivo Niglas (1970).Tema koos Frode Storaasiga tehtud dokumentaalfilm vihma loitsimisest Aafrikas "Vihmategemine" (Eesti - Norra - Mosambiik 2007) esilinastus Tartus MaailmFilmi festivalil. Lisatud andmed hariduse ja loomingu kohta

  20. "Kuninganna" Tallinnas / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2007-01-01

    Tänasest on Sõpruse kinos Stephen Frearsi mängufilm "Kuninganna" ("The Queen") : stsenarist Peter Morgan : kuninganna Elizabeth II kehastab Helen Mirren, peaminister Tony Blair'i Michael Sheen. Lisatud andmed Helen Mirreni kohta

  1. Jüri Kraft / Jüri Kraft ; interv. Tiina Jõgeda

    Index Scriptorium Estoniae

    Kraft, Jüri, 1935-

    2004-01-01

    Autori meenutusi õpingutest Tartu Ülikooli majandusteaduskonnas, direktori ametist Sangaris ja Klementis, tööst kergetööstusministeeriumis ning ministrina. Lisatud Jüri Krafti olulisemad eluloolised andmed

  2. Vahur Kraft / Vahur Kraft ; interv. Tiina Jõgeda

    Index Scriptorium Estoniae

    Kraft, Vahur, 1961-

    2004-01-01

    Eesti Panga president õpingutest Tartu Ülikooli majandusteaduskonnas, tööst Mererajooni hoiukassade peavalitsuse osakonnajuhatajana ja Eesti Pangas, väärtushinnangutest, rahareformist. Lisatud Vahur Krafti olulisemad eluloolised andmed

  3. Vaesusriski muutused Eestis / Ene-Margit Tiit

    Index Scriptorium Estoniae

    Tiit, Ene-Margit, 1934-

    2006-01-01

    Seoses Eesti majanduse kiire arenguga tellis sotsiaalministeerium 2005. aastal uue tarbimiskaalude hinnangu, mille aluseks olid leibkonna eelarvehinnangu andmed aastaist 2000-2004 ning hinnati erineva struktuuriga leibkondade tarbimiskulutusi. Diagrammid. Graafikud

  4. Double standards: Differences in norms on voluntary childlessness for men and women / Arieke J. Rijken, Eva-Maria Merz

    Index Scriptorium Estoniae

    Rijken, Arieke J.

    2014-01-01

    Artiklis analüüsitakse vabatahtliku lastetuse normide erinevust meeste ja naiste puhul, nende normide sisu ja kujunemise põhjuseid, aluseks Euroopa sotsiaaluuringu (2006) andmed. Tuuakse välja riikidevahelised (sh Eesti) erinevused

  5. Rahvusvaheline metsandusstatistika = International forest statistics / M. Raudsaar

    Index Scriptorium Estoniae

    Raudsaar, Madis

    2007-01-01

    Andmed pärinevad ÜRO Toitlus- ja Põllumajandusorganisatsiooni (FAO) andmebaasist. Maailma ja Euroopa metsaressursid, ümarpuidu ja saematerjali, maailma paberi ja pabertoodete suurimad tootjad 1970-2005

  6. Rahvusvaheline metsandusstatistika = International forest statistics / M. Raudsaar

    Index Scriptorium Estoniae

    Raudsaar, Madis

    2008-01-01

    Andmed pärinevad ÜRO Toitlus- ja Põllumajandusorganisatsiooni (FAO) andmebaasist. Maailma ja Euroopa metsressursid, ümarpuidu ja saematerjali, maailma paberi ja pabertoodete suurimad tootjad 1970-2006

  7. Kalevipoeg - ein Interview mit Prof. Dr. Peter Petersen / Peter Petersen ; interv. Laine Paavo

    Index Scriptorium Estoniae

    Petersen, Peter

    2005-01-01

    Kalevipoja uuest saksakeelsest väljaandest: Kalevipoeg : das estnische Nationalepos / in der Übersetzung von Ferdinand Löwe ; herausgegeben von Peter Petersen Ilm. andmed Stuttgart ; Berlin : Mayer, 2004.

  8. President Rüütel valis endale Audi / Allar Viivik

    Index Scriptorium Estoniae

    Viivik, Allar

    2002-01-01

    President Arnold Rüütli uueks ametiautoks saab Audi A8. Arvamust avaldavad Reval Auto juht Aivar Toompere ja Silberauto pressiesindaja Üllar Born. Samas: Audi A8 tehnilised andmed ; Naabritel on esindusautod kallimad

  9. Jahindus = Hunting / Jüri Tõnisson, Kaarel Roht, Peep Männil

    Index Scriptorium Estoniae

    Tõnisson, Jüri, 1946-

    2007-01-01

    Jahimeeste poolt loendatavate ulukite arvukus ja küttimine. Statistilised andmed 1985-2005. aasta jahihooajast. Põdra arvukus ja küttimine 1960-2005. Erinevate jahiulukite populatsioonide seisund Eesti metsades. Tabelid, diagrammid, graafikud

  10. Jahindus = Hunting / Jüri Tõnisson, Kaarel Roht, Peep Männil

    Index Scriptorium Estoniae

    Tõnisson, Jüri, 1946-

    2008-01-01

    Jahimeeste poolt loendatavate ulukite arvukus ja küttimine. Statistilised andmed 1985-2006. aasta jahihooajast. Põdra arvukus ja küttimine 1960-2006. Erinevate jahiulukite populatsioonide seisund Eesti metsades. Tabelid, diagrammid, graafikud

  11. Self-perceived job insecurity across Europe over time: Does changing context matter? / Christiane Lübke, Marcel Erlinghagen

    Index Scriptorium Estoniae

    Lübke, Christiane

    2014-01-01

    Artikkel keskendub inimeste tööalasele ebakindlusele ning seda mõjutatavatele teguritele Euroopas (sh Eesti). Mitmetasandilise analüüsi aluseks on OECD vastavad indikaatorid ja Euroopa sotsiaaluuringu andmed

  12. Lugejad küsivad - autorid vastavad : [teemad: osaühingu raamatupidamine...] / Maire Otsus-Carpenter, Olesja Timofejeva, Häli Jürimäe ...[jt

    Index Scriptorium Estoniae

    2015-01-01

    Teemad: osaühingu raamatupidamine, sõiduauto liikluskindlustus rendiperioodil, OÜ käibemaksukohustuslasena registreerimine, arvel nõutavad andmed, deklaratsiooni parandamine, päevaraha maksmine lähetuse korral, allkirjastamise õiguse delegeerimine

  13. Why call it „equality” when it should be „achievement”? A proposal to un-correct the „corrected gender gaps” in the EU Gender Equality Index / Inaki Permanyer

    Index Scriptorium Estoniae

    Permanyer, Inaki

    2015-01-01

    Artiklis kritiseeritakse Euroopa Liidu Sotsiaalse Võrdõiguslikkuse Instituudi 2013. aastal väljapakutud soolise võrdõiguslikkuse indeksit, kuna see võib olla eksitav selle potentsiaalsetele kasutajatele. Esitatakse ka korrigeeritud andmed riikide (sh Eesti) kohta

  14. Eesti filmi "Jade Warrior" esilinastus Torontos / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2006-01-01

    Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina ja Eesti ühistöö) esilinastus eile Toronto filmifestivalil. Andmed filmi tootmise ja levitamise kohta

  15. Suhted õpetajatega kui õpilaste koolirõõmu ennustav tegur: eesti ja vene koolide võrdlus = Relationships Between Students and Teachers as a Predictor of School Motivation in Estonia and Russian Schools / Leida Talts, Eva-Maria Kangro, Maia Muldm

    Index Scriptorium Estoniae

    Talts, Leida, 1943-

    2013-01-01

    Artikkel käsitleb õpilaste ja õpetajate vaheliste suhete seoseid koolirõõmuga. Andmed tuginevad projekti "Aktiivne ja turvaline koolipäev - SAS" raames korraldatud uuringu osale, mis käsitleb õpilaste arvamusi suhete kvaliteedist koolikeskkonnas

  16. Iain Harvey - inglasest võlur-produtsent / Iain Harvey ; interv. Heilika Võsu

    Index Scriptorium Estoniae

    Harvey, Iain

    2003-01-01

    Londoni animafilmistuudio "The Illuminated Film Company" produtsent Pimedate Ööde Filmifestivali animafilmide festivali "Animated Dreams 2002" külalisena. Lisatud andmed I. Harvey loomingulise tegevuse kohta, lk. 103

  17. The increase in cohabitation and the role of union status in family policies: A comparison of 12 European countries / Nora Sánchez Gassen, Brienna Perelli-Harris

    Index Scriptorium Estoniae

    Sánchez Gassen, Nora

    2015-01-01

    Artiklis käsitletakse koos elavate, kuid abielus mitteolevate inimeste arvukust, nende õigusi/õigusetust 12 Euroopa riigis (sh Eesti), aluseks Euroopa sotsiaaluuringu andmed ning autorite moodustatud poliitika andmebaas

  18. Neftjanoi resurs estonskihh slantsev / Jevgeni Ašimin

    Index Scriptorium Estoniae

    Ašimin, Jevgeni

    2008-01-01

    Narva Õlitehas laiendab tootmist seoses nõudluse suurenemisega põlevkiviõli järele maailmaturul, uuendab seadmeid ning investeerib keskkonnasäästlikku tehnoloogiasse. Lisa: Andmed Narva Õlitehase kohta

  19. Representations of the past in the Estonian Russian-language press: „own” or diaspora memory / Triin Vihalemm, Valeria Jakobson

    Index Scriptorium Estoniae

    Vihalemm, Triin, 1968-

    2011-01-01

    Artiklis käsitletakse kollektiivse identiteedi küsimust venekeelsete elanike seas Eestis, aluseks 2009. aastal kohalikus venekeelses ajakirjanduses ilmunud ajaloosündmusi käsitlevad tekstid. Võrdlusena tuuakse andmed eestikeelsest ajakirjandusest. Tabelid

  20. Loodav register aitab kergemini leida usaldusväärset lapsehoidjat / Karin Kangro

    Index Scriptorium Estoniae

    Kangro, Karin

    2004-01-01

    Eestis valmistatakse ette lapsehoidjate kutsestandardit ja aastal 2006 avatakse riiklik register, kuhu võivad oma andmed kanda kõik kutseeksami sooritanud lapsehoidjad. Lisa: Tausta peaks põhjalikult uurima

  1. "Mõ prosto ne mozhem postupat inatshe..." / Josef Kats

    Index Scriptorium Estoniae

    Kats, Josef, 1977-

    2006-01-01

    Poola peaminister Kazimierz Marcinkiewiczi nägemus Poola osast Euroopa poliitilisel areenil, Eesti ajakirjanike kohtumisest peaministriga Eesti visiidi eel. K. Marcinkiewiczi eluloolised andmed ja poliitiline karjäär

  2. Raimond Valgre noorem vend - kes ta oli? : Kuno-Enn Valgre (30.05.1918-02.03.1987) / Valdur Ohmann

    Index Scriptorium Estoniae

    Ohmann, Valdur, 1958-

    2011-01-01

    Vastukäivad andmed ärgitasid uurima, kes õigupoolest oli Valgre noorem vend. Kõige ehedamalt annab Enn Valgre sõjaaegse käekäigu edasi ülekuulamisprotokoll 11. novembrist 1944. Ülekuulamisprotokolli tekst

  3. Economic performance and political trust: the impact of the financial crisis on European citizens / Veronica Fagerland Kroknes, Tor Georg Jakobsen, Lisa-Marie Gronning

    Index Scriptorium Estoniae

    Fagerland Kroknes, Veronica

    2015-01-01

    Artiklis käsitletakse majandusliku olukorra (konkreetselt 2007-2008. aasta majanduskriisi) ja poliitilise usalduse seoseid Euroopa eri riikides (sh Eesti), aluseks Euroopa sotsiaaluuringu, Maailmapanga ja Rahvusvahelise Valuutafondi andmed

  4. Institutional context and representational strain in party-voter agreement in Western and Eastern Europa / Robert Rohrschneider, Stephen Whitefield

    Index Scriptorium Estoniae

    Rohrschneider, Robert

    2012-01-01

    Uus teoreetiline seletus valimisinstitutsioonide mõjust poliitika ühildumisele, võttes arvesse valijate kasvavat jagunemist, nt partisanid ja sõltumatud. Aluseks 24 Euroopa riigi (sh Eesti) andmed. Joonised, tabelid

  5. Vastaspoolte inimkaotustest Narva rindel 1944. aasta 24. juulist kuni 7. augustini (Narva ja Sinimägede lahingud) / Artjom Astafjev, Andrus Kütt, Reigo Rosenthal

    Index Scriptorium Estoniae

    Astafjev, Artjom

    2015-01-01

    Fotod dokumentidest ja tabelid inimkaotustest. Kokkuvõttes võib Punaarmee kaotusi nendes lahingutes hinnata 35 000 inimesele, Saksa vägede kaotusi hinnatakse umbes 10100 inimeseni. Andmed on ligikaudsed

  6. The role of cultural context in explaining cross-national gender gaps in STEM expectations / Anne McDaniel

    Index Scriptorium Estoniae

    McDaniel, Anne

    2016-01-01

    Artiklis käsitletakse naiste esindatuse põhjusi loodus- ja tehnikateadustes, tehnoloogias ja matemaatikas, aluseks 24 riigi (sh Eesti) Euroopa sotsiaaluuringu ja Maailmapanga üliõpilaste ametialaste ootuste uuringu andmed

  7. Kohandumatu vs kohandamatu / Mari Laaniste

    Index Scriptorium Estoniae

    Laaniste, Mari, 1977-

    2007-01-01

    Mängufilm "Kuidas kirjutada kassafilmi" ("Adaption") : stsenarist Charlie Kaufman : režissöör Spike Jonze : peaosades Nicolas Cage : Ameerika Ühendriigid, 2002. Lisatud andmed ja filmograafia Charlie Kaufmani kohta

  8. Sõidukite parkimiskorra kehtestamine : [29.09.1999

    Index Scriptorium Estoniae

    2000-01-01

    Lisa 1: Valveta tasulised parkimisalad Tallinna linna omandis või valduses olevatel teedel Lisa 2: Sõidukite valveta tasulise parkimise hinnad Tallinna linna omandis või valduses olevatel teedel Lisa 3: Sõidukite ümberpaigutamise ja hoiukohas hoidmise tariifid Lisa 4: Trahvinõudel esitatavad andmed Lisa 5: Sõiduki valvega hoiukohta paigutamise aktil esitatavad andmed Lisa 6: Sõidukite parkimise sooduslubade väljaandmise kord

  9. Tulumaksu laekumine on olnud hea / Urmas Kiil

    Index Scriptorium Estoniae

    Kiil, Urmas

    2008-01-01

    11 kuu andmed näitavad, et Saare maakonnas tervikuna peaks 2008. aasta tulumaksu laekumise plaan täituma. Diagrammid: Füüsilise isiku tulumaksu laekumine saare maakonna omavalitsustes 2008. a. 11 kuu andmed: laekumise % 2009. a. kavandatud eelarvest; Üksikisiku tulumaksu laekumise tempo aastatel 2007 ja 2008 (11 kuu laekumised võrreldes eelneva aasta sama perioodiga). Kommenteerib Kihelkonna vallavanem Jüri Saar

  10. Surprising similarities: Recent monetary regimes of small economies / Andrew K. Rose

    Index Scriptorium Estoniae

    Rose, Andrew K.

    2014-01-01

    Artikkel keskendub väikese majandusega riikide (sh Eesti) rahapoliitikale enne ja pärast ülemaailmset finantskriisi. Kokku analüüsitakse 170 riigi näitajaid aastatest 2007-2012 ning jõutakse järeldusele, et riikide rahapoliitika mõju makromajanduslikele ja finantstagajärgedele on tegelikult üllatavalt väike

  11. The avant-garde is not dead / René Block ; intervjueerinud Eero Epner

    Index Scriptorium Estoniae

    Block, René, 1942-

    2010-01-01

    Intervjuu saksa galeristi ja kuraatori René Blockiga, kes 1964. a. avas Berliinis galerii, kus eksponeeris J. Beuysi, S. Polke, G. Richteri jt. töid. Töötamisest kuraatorina alates 1970. aastatest, biennaalide tulevikust, avangardist. René Blocki galeriis 1966. a. toimunud Joseph Beuys'i performance'ist "Kuidas seletada kunsti surnud jänesele", millest inspireerituna teater NO99 lõi samanimelise lavastuse

  12. Kiasmas saab ülevaate kaasaegse kunsti (ja elu) problemaatikast / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2005-01-01

    Seppo Renvalli retrospektiiv Taidehallis. Eksponeeritud 1990-ndate algul tehtud pinhole-säritusi, paar fotoseeriat, üle kümne 16mm kinofilmi ja video aastatest 1991-2005, installatsioon "The Ball Show" (1998-2001). Poliitilise kaasaegse kunsti väljapanek "Fractures of Life" Kiasma kollektsioonidest. Kuraatorid Tuula Karjalainen, Marja Sakari, Eija Aarnio, Leena-Maija Rossi, Erkki Berndson. Eesti kunstnike loomingust oli väljas Jaan Toomiku video "Untitled" (2001). Santiago Serra teosest

  13. Outcome Studies on the Efficacy of Art Therapy: A Review of Findings

    Science.gov (United States)

    Slayton, Sarah; D'Archer, Jeanne; Kaplan, Frances

    2010-01-01

    In response to a review by Reynolds, Nabors, and Quinlan (2000) of the art therapy literature prior to 1999, this review article identifies studies from 1999-2007 that measured outcomes of art therapy effectiveness with all ages of clinical and nonclinical populations. Although numerous studies blend art therapy with other modalities, this review…

  14. Impeachment Imbroglio and “The Impeachment of Reason” in ...

    African Journals Online (AJOL)

    Impeachment Imbroglio and “The Impeachment of Reason” in Nigerian Politics, 1999-2007. ... Since Nigeria borrowed the constitutional system she purports to practise from the U.S.A, the U.S. experience is brought to bear. The paper argues that in the U.S.A. impeachment is straight forward enough; it is a matter strictly ...

  15. Effect van "Ruimte voor Geo-informatie" op GIScience in Nederland : eindrapport RGI-402

    NARCIS (Netherlands)

    Veller, van M.G.P.; Fransen, H.; Duizendstraal, M.B.; Gerritsma, W.

    2009-01-01

    This report describes bibliometric analyses of the scientific output of GIScience in the Netherlands over the period 1999-2007. The bibliometric analyses have been based upon bibliographic data from articles published in 12 peer reviewed GIScience journals, articles in two professional journals and

  16. Trend in the use of Intra-uterine Contraceptive Device (IUCD ,TCU ...

    African Journals Online (AJOL)

    OBJECTIVE: To estimate the acceptance rate and trend of Intrauterine Contraceptive Device (IUCD) use in Enugu,Nigeria PATIENTS AND METHODS: A review of all new acceptors of intrauterine contraceptive device (IUCD) over a nine year period(1999-2007) . RESULTS: A total of 133,375 clients were seen at the UNTH ...

  17. Democracy and poverty reduction in Nigeria: A case study of Rivers ...

    African Journals Online (AJOL)

    This paper seeks to examine the extent to which Nigeria's democratic experience (1999-2007) has elevated the living standards of the majority of the people. It specifically aimed at search lighting the impact of the regime's key poverty reduction strategies vis-à-vis the overall poverty situation in the country in general and ...

  18. How Many Brains Does It Take to Build a New Light: Knowledge Management Challenges of a Transdisciplinary Project

    Science.gov (United States)

    della Chiesa, Bruno; Christoph, Vanessa; Hinton, Christina

    2009-01-01

    The Organization for Economic Cooperation and Development's (OECD) Center for Educational Research and Innovation (CERI) carried out the "Learning Sciences and Brain Research" project (1999-2007) to investigate how neuroscience research can inform education policy and practice. This transdisciplinary project brought many challenges. Within the…

  19. Arheologi otkrõli fragment sten na gorke Harju / Urmas Seaver

    Index Scriptorium Estoniae

    Seaver, Urmas, 1973-

    2008-01-01

    Tallinna Vabadussamba asukoha ettevalmistustööde käigus leidsid arheoloogid Harjumäel fragmendi ajaloolisest Ingeri bastioni müürist. Arheoloogiliste kaevamistega saadavad andmed on vajalikud lõpliku eskiisprojekti koostamiseks. Vastavalt monumendi projektile avatakse bastioni müürid eksponeerimiseks

  20. St George's Cemetery in Tartu - Medieval Burial Ground of the Leprosarium? / Martin Malve, Anti Lillak, Raido Roog, Mihkel Mäesalu

    Index Scriptorium Estoniae

    2013-01-01

    Varasemad andmed Püha Jüri hospidalist Tartus pärinevad 1345. aastast. Asutus tegutses 17. sajandi esimese pooleni. Küsimus aga, kas korduvalt uuritud Püha Jüri kalmistu ja keskaegne hospidalikalmistu on üks ja sama objekt, jääb praeguses uurimisseisus kindla vastuseta

  1. I am Crazy in Loving You / Aarne Ruben

    Index Scriptorium Estoniae

    Ruben, Aarne, 1971-

    2003-01-01

    Palestiina režissööri Elia Suleimani mängufilm "Jumalik sekkumine" ("Yadon ilaheyya") ja bosnia režissööri Danis Tanovici "Eikellegimaa" ("No Man's Land"). Lisatud andmed režissööride kohta lk. 102

  2. "Mul oli tunne, et sõidaksin nagu kihlusele" / Verni Leivak

    Index Scriptorium Estoniae

    Leivak, Verni, 1966-

    2002-01-01

    W. Shakespeare'i "Romeo ja Julia", Eesti Draamateatri Vene Draamateatri ühistööna, lavastaja A. Prosa, osades J. Rudina Peterburist ja M. Malmsten. Lisatud andmed külalisnäitleja J. Rudina ja "Romeo ja Julia" aluseks olnud linnalegendide kohta

  3. Toomkiriku Saueri orel saab korda! / Hugo Lepnurm, Toomas Mäeväli ; interv. Alo Põldmäe

    Index Scriptorium Estoniae

    Lepnurm, Hugo, 1914-1999

    1998-01-01

    Prof. Hugo Lepnurm ja orelimeister Toomas Mäeväli Toomkiriku Saueri oreli restaureerimise käigust saksa firmas Orgelwerkstatt Christian Scheffler. Oreli sisseõnnistamine 1. augustil 1998. Samas andmed oreli elukäigust. Oreli ehitas 1858. a. saksa meister Friedrich Ladegast. Eestis viimasel ajal töökorda saadud teistest orelitest.

  4. Income inequality and depression: the role of social comparisons and coping resources / Ioana van Deurzen, Erik van Ingen; Wim J. H. van Oorschot

    Index Scriptorium Estoniae

    Deurzen, Ioana van

    2015-01-01

    Artiklis käsitletakse sissetulekute ebavõrdsuse ja depressiooni seoseid, pöörates tähelepanu riikidevahelistele erinevustele ja seda mõjutavatele faktoritele Euroopa riikides, sh Eesti. Aluseks on Euroopa sotsiaaluuringu (2006/2007) andmed

  5. Vastab Peter Greenaway / Peter Greenaway ; interv. Elen Lotman

    Index Scriptorium Estoniae

    Greenaway, Peter, 1942-

    2005-01-01

    Inglise filmirežissöör ja kunstnik Eestis PÖFFi aukülalisena juba pärast festivali lõppu, jaanuaris 2005. Lisatud lühike elulugu, filmograafia ja andmed tema kohta kirjutatud artiklitest ajakirja varasemates numbrites lk. 14-15

  6. Does the cultural context matter? The effect of a country's gender-role attitudes on female labor supply / Wilfred Uunk

    Index Scriptorium Estoniae

    Uunk, Wilfred

    2015-01-01

    Artikkel käsitleb egalitaarsete soorollide kui kultuurikonteksti ühe olulise komponendi mõju naiste osalemisele tööturul. Analüüsi aluseks on 33 riigi (sh Eesti) 2008. aasta Euroopa väärtusuuringu andmed

  7. Pärandkultuur - muinsuskaitse reserv / Jüri Kusmin, Vaike Pommer

    Index Scriptorium Estoniae

    Kusmin, Jüri

    2008-01-01

    Riigimetsa Majandamise Keskuse initsiatiivil ja Euroopa struktuurifondide toel viidi aastatel 2005-2007 Eesti neljas maakonnas - Läänemaa, Raplamaa, Harjumaal ja Järvamaal - läbi metsandusliku pärandkultuuri inventuur. Kaardistatud on enam kui 6300 objekti. Andmed on kantud Maa-Ameti andmebaasi geoportaali X-GIS.

  8. Eesti Euroopa Liidus. Missugused oleme võrreldes teiste liikmesriikidega? / Külvar Mand, Väino Sinisalu

    Index Scriptorium Estoniae

    Mand, Külvar, 1965-

    2004-01-01

    Euroopa Liidu uute liikmesriikide tervishoiuvaldkonda puudutavad statistilised näitajad võrrelduna senise 15 liikmesriigi andmetega (demograafilised näitajad, eeldatav tervena elatud elu kestus, suremus, suitsiidide esinemissagedus, haigestumus tuberkuloosi, sagedamini esinevad haiguste riskitegurid, arstiabi ressursid, kulutused arstiabile). Andmed tuginevad Maailma Tervishoiuorganisatsiooni WHO poolt 2004. a. avaldatud raamatule "10 Health Questions about the 10"

  9. Jüri 22 ärihoone-elamu - Võru esimene pilvelõhkuja / Ivi Laatsit

    Index Scriptorium Estoniae

    Laatsit, Ivi

    2004-01-01

    1923. a. arhitekt Artur Perna (1881-1940) projekti järgi valminud Tarvitajate Ühisuse Põllumees uuest hoonest ja selle ajaloost. Lühidalt 2001. a. Ilmar Jalase projekteeritud Wõro Kommertsi ärihoonest ja Artur Perna biograafilised andmed

  10. Ühe sümptomi kirjeldus - Sillamäe Jeanne D'Arc / Karol Ansip

    Index Scriptorium Estoniae

    Ansip, Karol

    2003-01-01

    Dokumentaalfilm Sillamäe pensionäride ühenduse aktivisti Esja Shuri võitlusest oma õiguste eest "Meeleavaldaja" : stsenarist, režissöör ja produtsent Meelis Muhu : operaator Erik Norkroos : In Ruum 2003. Lisatud andmed M. Muhu senise loomingu kohta lk. 112

  11. Abielluda! Abielluda! Abielluda! / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2008-01-01

    Lühiarvustus Jane Austeni romaani ekraniseeringule "Mõistus ja tunded" ("Sens and Sensibility") : stsenarist Emma Thompson : režissöör Ang Lee : Suurbritannia - Ameerika Ühendriigid 1995. Lisatud andmed režissööri kohta

  12. Winners and losers in transition: preferences for redistribution and nostalgia for communism in Eastern Europe / Adam Okulicz- Kozaryn

    Index Scriptorium Estoniae

    Okulicz- Kozaryn, Adam

    2014-01-01

    Artikli teema on üleminekuperioodi võitjad ja kaotajad Ida-Euroopas (sh. Eesti), täpsemalt käsitletakse nostalgiat kommunismi järele. Andmed pärinevad uurimusest „Demokraatia konsolideerumine Kesk- ja Ida-Euroopas 1990-2001”.

  13. Siin ta siis ongi: USA õnnelikem inimene / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2011-01-01

    Uuringufirma Gallup ja tervise edendamisele pühendunud ettevõtte Healthways poolt läbiviidud uuringu käigus saadi teada, milline on statistiliselt USA kõige õnnelikum inimene. Ajaleht New York Times võttiski aluseks Gallupi andmed ja otsis üles statistilistelt näitajatelt kõige õnnelikuma USA inimese, kelleks osutus Alwin Wong

  14. 75 FR 9228 - Draft Guidance for Industry on Non-Inferiority Clinical Trials; Availability

    Science.gov (United States)

    2010-03-01

    ... to determine the non-inferiority margin for use in NI studies, as well as the advantages and disadvantages of available methods. The third part addresses commonly asked questions about NI studies and....m. and 4 p.m., Monday through Friday. III. Electronic Access Persons with access to the Internet may...

  15. Irene Väli / Ruth Alas

    Index Scriptorium Estoniae

    Alas, Ruth, 1960-2018

    2007-01-01

    AS Haapsalu Kuurort juhataja Irene Väli juhtimispõhimõtted, muudatuste elluviimise taktika, karjäär, väärtushinnangud, organisatsiooni arenguvõimalused, puhkus ja perekond. Eluloolised andmed, haridus, töökogemus. Kommenteerib kuurordi ilukeskuse juhataja Merle Murik

  16. Lapse saamise ajastamine ja laste arv : sündimustrendid Euroopas / Mare Ainsaar

    Index Scriptorium Estoniae

    Ainsaar, Mare, 1966-

    2011-01-01

    Artiklis näidatakse kuidas sündimuse analüüsiks kasutatavad teooriad aitavad seletada väärtuste, normide ja ressursside mõju sündimuskäitumisele. Aluseks empiirilised andmed Euroopa riikides 2006. a. sündimuse kohta läbi viidud Eurobaromeetri uuringust (Testa 2006)

  17. Normative climates of parenthood across Europe: judging voluntay childlessness and working parents / Veronique Eicher, Richard A. Settersten, Sandra Penic ...[jt.

    Index Scriptorium Estoniae

    2016-01-01

    Artiklis käsitletakse ühiskonna normatiivse kliima mõju indiviidi hoiakutele kahe ebatraditsioonilise soorolli (vabatahtlik lastetus ja töötamine täistööajaga ajal, mil lapsed on väiksed) puhul, aluseks 21 riigi (sh Eesti) Euroopa sotsiaaluuringu andmed

  18. Tarkvarapiraatluse osakaal Eestis on 54%

    Index Scriptorium Estoniae

    2004-01-01

    IDC uuringu andmed tarkvarapiraatluse tasemest Eestis. Piraattarkvara laialdasest levikust Eestis ja selle kasutamise eest ette nähtud karistustest räägivad legaalse tarkvara kasutust kontrolliva organisatsiooni BSA juriidiline nõustaja Kaido Uduste ja julgestuspolitsei esindaja Hannes Järvine

  19. Essays on Strategy. Hostage Rescue Planning, Maritime Theater Nuclear Capability, Strategic Psychological Operations

    Science.gov (United States)

    1985-01-01

    lawa.gnw: (the f irst t LI11IX contaInerized ship In thu i Merchant fleet) had been en rou~tC fromn Hong Kong to S-attlahirp Tha I andm, with a carga , ot...other means; and to strengthen the institutions of democracy through work with labor unions, democratic political parties, media, and universities

  20. Hypothesis: Leukocyte Endogenous Mediator/Endogenous Pyrogen/Lymphocyte-Activating Factor Modulates the Development of Nonspecific and Specific Immunity and Affects Nutritional Status

    Science.gov (United States)

    1982-04-01

    Althoughmalnutrition ~ ~ ~ . ma1 pyrdc h via . Merriman CR. Pulliam LA. Kampschmidt RF. malnutrition may simply reduce the availa- Comparison of leukocytic pyrogen and...Med 21. Powanda MC, Sammons ML. Stephen EL. Systemic 1972:141:1029-31. metabolic alterations associated with repeated injec- 38. Goldstein IM. Kaplan HB

  1. Tänavu oli M&A tehingute murdepunkt / Kristin Ojamäe

    Index Scriptorium Estoniae

    Ojamäe, Kristin

    2004-01-01

    2004. aastal on taaskord näha ettevõtete ühinemis- ja ostu-müügitehingute arvu ja mahu kasvu. 11 kuu andmed näitavad võrreldes 2003. aasta sama perioodiga 47%-list kasvu lõpule viidud tehingute mahtudes. Diagramm: Tehingute tippaeg jääb 2000. aastasse

  2. Piinlik juhtum Nordeconi jaoks / Hannes Sarv ; kommenteerinud Mihkel Mugur

    Index Scriptorium Estoniae

    Sarv, Hannes

    2010-01-01

    Merko palus üle kontrollida Nordecon Infra esitatud andmed Sillamäe Veevärgi riigihankel, riigihangete amet algatas Nordeconi suhtes väärteomenetluse, mis viis Nordecon Infra juhtivtöötaja Priit Pluutuse trahvimiseni. Trahv on kohtus vaidlustatud

  3. Täägid paradiisis / Colin MacCabe ; tõlk. Indrek Koff

    Index Scriptorium Estoniae

    MacCabe, Colin

    1999-01-01

    Mängufilm "Peenike punane joon" ("The Thin Red Line") : režissöör ja stsenarist James Jonesi romaani põhjal Terrence Malick : Ameerika Ühendriigid 1998. Lisa : Terrence Malickþi elu- ja loominguloolised andmed

  4. Zuroff : Meil on piisavalt materjali Harry Männili süüdimõistmiseks / Efraim Zuroff ; interv. Rasmus Kagge, interv. Erkki Bahovski

    Index Scriptorium Estoniae

    Zuroff, Efraim, 1948-

    2001-01-01

    Simon Wiesenthali Keskuse Iisraeli büroo direktori väitel on neil piisavalt materjali, et mõista Harry Männili süüdi natsikuritegudes. Vt. samas R. Kagge Eestis puuduvad andmed Männili kuritegude kohta

  5. Veidrikest, meist kõigist / Jan Kaus

    Index Scriptorium Estoniae

    Kaus, Jan, 1971-

    2002-01-01

    Kolm noorte filmitegijate dokumentaalfilmi : Ralf Siia portreefilm poliitik Tiit Toomsalust "Vastlasõit", Kaidor Kahari "Varastati rõngasrist" ning Elen Lotmani portree Aleksei Lotmanist, kelle hoole all on Matsalu looduskaitseala "Homo sapiens". Lisatud andmed noorte režissööride kohta lk. 112

  6. Naine kohtub Hundiga - püüne peal / Kaja Kann, Bush Hartshorn

    Index Scriptorium Estoniae

    Kann, Kaja, 1973-

    2006-01-01

    Kanuti Gildi saalis etendub 26.-28. veebr. Kaja Kanni ja Bush Hartshorni lavaduett "Naine ja Hunt". Autorid räägivad, kuidas nad käisid Pärnumaa laantes oma lavaloole õiget tunnetust otsimas. Lisatud andmed Bush Hartshorni kohta

  7. Ühe jalaga Hollywoodis / Airi Ilisson

    Index Scriptorium Estoniae

    Ilisson, Airi, 1980-

    2005-01-01

    USAs elava filmirežissööri Jaanus Silla initsiatiivil Eestist ja Eesti filmitegijatest huvitunud Hollywoodi produtsendi Anne Marie Gillen'i ettepanekud Eesti filmirahastajatele. Lisatud andmed Jaanus Silla ja Anne Marie Gilleni kohta ning Ilmar Raagi, Tiina Loki ja Peeter Rebase kommentaarid

  8. Täna esilinastub USA-Eesti koostööfilm / Artur Veeber ; interv. Valdo Jahilo

    Index Scriptorium Estoniae

    Veeber, Artur

    2001-01-01

    Filmist "Virtuoos" ("Out of the Cold"), režissöör Aleksandr Buravsky : Ameerika Ühendriigid - Eesti 1999. Samas toodud andmed filmi ja tegijate kohta. Eraldi lühike intervjuu Tõnu Aavaga "Tõnu Aav ülemteenri rollis"

  9. Viron kirjallisuuden kieli 1990-luvulla modernismin, postmodernismin ja postkolonialismin taustaa vasten / Tiit Hennoste ; tõlk. Niko Remes

    Index Scriptorium Estoniae

    Hennoste, Tiit, 1953-

    2003-01-01

    Andmed autori kohta lk. 237. Orig.: Eesti kirjanduse keelest modernismi, postmodernismi ja postkolonialismi taustal. Ilmunud ka kogumikus: Hennoste, Tiit. Eurooplaseks saamine : kõrvaltkäija altkulmupilk. Tartu : Tartu Ülikooli Kirjastus, 2003, lk. 202-231. Bibliograafia lk. 229-231

  10. Arengud maailma turismis 2003 / Piret Kallas

    Index Scriptorium Estoniae

    Kallas, Piret

    2004-01-01

    2003. aasta statistilised andmed turismi ja reisimise kohta. Tabelid: Ööbimisega reisid maailmas regiooniti, 1990-2003; Väliskülastajate saabumised Eestisse, 1996-2003; Väliskülastajate saabumised Eestisse transpordiliikide lõikes, 2001-2003; Eesti majandusettevõtetes majutatud turistid ja nende ööbimised, 2001-2003

  11. Do more competitive banks have less market power? The evidence from Central and Eastern Europe / Ion Lapteacru

    Index Scriptorium Estoniae

    Lapteacru, Ion

    2014-01-01

    Artikkel käsitleb Kesk- ja Ida-Euroopa pankade konkurentsivõimelisust, püüdes vastata küsimusele, kas konkurentsivõimelisemad pangad omavad tegelikkuses vähem turujõudu ning millistel tingimustel on turujõud suurem. Aluseks 298 kommertspanga (sh Eesti) andmed.

  12. Download this PDF file

    African Journals Online (AJOL)

    De Don

    Cow, dog, goat and poultry faeces and the control medium of rice and fish supported the development of eggs in female C. chloropyga andM domestica. Eggs of ..... chicken, cat, poultry and sheep faeces are relatively low in protein, relatively longer ... growth, development and reproduction. Thus, the inadequate food during ...

  13. Ori ei tahagi vabaks / Isaach De Bancole ; interv. Jaan Ruus

    Index Scriptorium Estoniae

    De Bancole, Isaach

    2008-01-01

    Mängufilm "Manderlay" : režissöör Lars von Trier : Taani - Rootsi - Holland - Prantsusmaa - Saksamaa - Ameerika Ühendriigid 2005. Lühiintervjuu annab filmi mustanahaline peaosaline. Lisatud andmed režissööri kohta

  14. Informatsiooni ebatäielikkuse mõju kõrgharidusnõudluse kujunemisele Eesti majandusüliõpilaste näitel / Tõnis Eerme

    Index Scriptorium Estoniae

    Eerme, Tõnis

    2004-01-01

    Uuringu tulemustest selgus, et 4. aasta üliõpilased hindasid oma lõpetamisjärgset palka kõrgemaks kui tööturu tegelikud andmed eeldanuks. Selle põhjuseks võib olla ebatäiuslik informatsioon. Probleemi lahendaks riikliku kutsenõustamissüsteemi arendamine, leiab autor. Tabel. Diagramm

  15. The differential effects of bilateral tax treaties / Bruce A. Blonigen, Lindsay Oldenski, Nicholas Sly

    Index Scriptorium Estoniae

    Blonigen, Bruce A.

    2014-01-01

    Artikli käsitletakse kahepoolsete maksulepingute mõju rahvusvahelisele majandustegevusele, eelkõige välismaistele otseinvesteeringutele, aluseks USA majandusanalüüsi büroo andmed. Teiste riikide seas on USA sõlminud lepingu ka Eestiga

  16. Tea Varrak / Ruth Alas

    Index Scriptorium Estoniae

    Alas, Ruth, 1960-2018

    2007-01-01

    Rahandusministeeriumi kantsler Tea Varrak iseloomustab ennast juhina, alluvate motiveerimine, ülevaade tavalisest tööpäevast, plaanid lähitulevikuks. Eluloolised andmed, haridus, täienduskoolitus, töökogemus. Kommenteerivad justiitsministeeriumi kantsler Jüri Pihl ja rahandusministeeriumi arendusjuht Alar Kolk

  17. Vaevaline koostöö uute kunstimuuseumide rajamise ja rahastamise protsessis = Thorny collaboration in the processes of founding and funding new art museums : II koht teaduspublikatsioonide kategoorias / Margaret Tali, Laura Pierantoni

    Index Scriptorium Estoniae

    Tali, Margaret

    2009-01-01

    Uuring tutvustab võrdlevalt uute kunstimuuseumide rajamisega seotud motivatsioone kolmes riigis ning mahukate ehitusprojektide rahastamist, keskendudes uute huvigruppide rollile Ida-Euroopa riiklike kunstimuuseumide tegevuses. Töö andmed on kogutud koostöös kolme muuseumiga: LUMU kunstimuuseum Budapestis, KUMU kunstimuuseum Tallinnas ja MSU kunstimuuseum Zagrebis

  18. "Sõrmuste isandast" - filmist, raamatust, müütidest ja kultuurist / Erkki Luuk

    Index Scriptorium Estoniae

    Luuk, Erkki, 1971-

    2003-01-01

    J.R.R. Tolkieni "Sõrmuste isanda" järgi loodud Peter Jacksoni kaks filmi - "Sõrmuste isand : Sõrmuste vennaskond" ("The Lord of the Rings : The Fellowship of the Ring") ja "Kaks kantsi" ("The Lord of the Rings : The Two Towers"). Ekraniseeringute vastavusest raamatutele. Lisatud andmed Peter Jacksoni kohta lk. 108

  19. IJS v10 n1.cdr

    African Journals Online (AJOL)

    De Don

    in female C. chloropyga andM domestica. Eggs of C. Chloropyga laid on the cow, dog goat and poultry as well as those of M. domestica laid on cow faeces did not hatch. Dog, goat and poultry faeces serve as useful nutrient for development of M domestica and compete favourably with the control medium. Poultry faeces on ...

  20. Working-time regimes and work-life balance in Europe / Timo Anttila, Toimi Oinas, Mia Tammelin, Jouko Nätti

    Index Scriptorium Estoniae

    2015-01-01

    Artiklis analüüsitakse töötingimusi suuresti määravat ajalist ja ruumilist paindlikkust ja nende seost töö- ja eraelu tasakaalustatusega. Aluseks Euroopa töötingimuste uuringu (2010) 25 liikmesriigi (sh Eesti) andmed

  1. Kunstnike elulood

    Index Scriptorium Estoniae

    2003-01-01

    Tallinna Rakenduskunsti triennaalil 2003 esinenud kunstnike eluloolised andmed, haridustee, näituste nimekiri, preemiad: Eija Mustonen, Ida Björs, Iris Eichenberg, Anna Katriina Tilli, Mari Relander, Claus Domine Hansen, Lene Hald, Line Gottfred Peterson, Anders Ruhwald, Audrius Janushonis, Lina Jonikiene, Jolanta Kvashyte, Eimantas Ludavicius, Aigi Orav, Remigijus Sederevicius, Adolfas Shaulys, Mari Relo-Shaulys, Mari-Liis Tammi

  2. Nukufilm, mis pani kihama kogu Soome / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2008-01-01

    Nukufilm "Uurali liblikas" (peategelaseks marssal Mannerheim) : režissöör Katariina Lillqvist : Soome 2008. Filmi esitleb Tallinnas K. Lillqvist uuel sariüritusel Animateek, mille taga seisavad festival Animated Dreams, EKA ja Kumu auditoorium. Lisatud andmed režissööri ja Animateegi kohta

  3. J. Randvere Ruth ja Otto Weiningeri Geschlecht und Charakter / Mirjam Hinrikus

    Index Scriptorium Estoniae

    Hinrikus, Mirjam, 1972-

    2004-01-01

    Naise kirjeldus J. Randvere "Ruthis" ja Otto Weiningeri "Geschlecht und Charakter'is". Andmed autori kohta lk. 202. Ilmunud ka kogumikus: J. Randvere "Ruth" 19.-20. sajandi vahetuse kultuuris / koost. Mirjam Hinrikus. Tallinn : Underi ja Tuglase Kirjanduskeskus, 2006, lk. 145-169

  4. On legal bases and process of accreditation of teaching of law in Estonia (University of Tartu Faculty of Law case) / Kalle Merusk, Raul Narits, Peep Pruks

    Index Scriptorium Estoniae

    Merusk, Kalle, 1949-

    1998-01-01

    Õigusharidust andvate õppeasutuste akrediteerimisest; Tartu Ülikooli õigusteaduskonnast ning selle avaliku õiguse ja eraõiguse instituutidest, õppeprogrammist, magistri- ja doktoriõppest ning teadustegevusest. Lisatud andmed 1993.-1998. a. kaitstud teadustööde kohta, õppejõudude osalemise kohta seaduseelnõude ettevalmistamisel ning publikatsioonide kohta

  5. Põltsamaa loss / Christian Gottlieb Welté, Stavenhagen Wilhelm Siegfried, Johann Michael Graff

    Index Scriptorium Estoniae

    Welté, Christian Gottlieb, 1748/49-1792

    1996-01-01

    Lk. 58 (17. saj. pärinevad figuraalsed ahjukahlid), värv., lk. 59 (fragment 1815. a. alevi kaardist), värv., lk. 221 (sisevaated 1770. aastatest, rokokoodekoor J. M. Graff, reprod TÜ kunstikabineti kogust), lk. 222 (lossiansambel, G. Chr. Velté õlimaal 18. saj. lõpust), värv., lk. 223 (loss ja kirik, G. Chr. Velté õlimaal 18. saj. lõpust), värv., lk. 224 (ampiirstiilis ahi härrastemaja saalis), värv., lk. 225 (loss ja alev, W. S. Stavenhageni gravüür 1867)

  6. Sissejuhatus / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati, 1937-

    1997-01-01

    Sisu: Probleemid ; 1. Astmevahelduse ja prosoodia käsitlemine 1840-ndatest aastatest (Faehlmann, Ahrens) kuni 1980-ndate aastateni ; 2. Prosoodia eesti keele häälikusüsteemi vahendina ja astmevaheldus eesti keele tüvefleksiooni nähtusena ning nende tänapäevane produktiivsus ; 3. Astmevahelduse areng aglutinatiivsest allofoonilisest variatsioonist morfofonoloogiliseks vahelduseks. Laadivaheldus keeletüpoloogiliselt ; 4. Hilise vältevahelduse võimalik kujunemine analoogia mõjul ; 5. Pikkade foneemide küsitavus ; 6. Eesti astmevahelduse tsüklid ; Sissejuhatuse bibliograafia

  7. Eesti koolilaps sõnaraamatu kasutajana

    Directory of Open Access Journals (Sweden)

    Ruth Mägi

    2006-05-01

    Full Text Available Artiklis antakse ülevaade Eesti koolilaste seas 2004/ 2005. õppeaastal läbiviidud uuringust, mille eesmärk oli välja selgitada õpilasest sõnaraamatukasutaja harjumused ja kogemused, kasutamisprobleemid, samuti rahulolu oma oskustega. Uuringu käigus küsitleti ühtekokku 369 koolilast 4.–12. klassist. Mujal maailmas on sõnaraamatute kasutamist uuritud ligikaudu 50 aastat, 1980. aastatest alates võib kõnelda lausa omaette uurimissuunast. Eestis pole sedalaadi uuringuid seni tehtud, siinne kirjutis on seega esimene katse kirjeldada eesti sõnaraamatute kasutamist.

  8. Eesti laevaehituse uus algus / Aldur Vunk

    Index Scriptorium Estoniae

    Vunk, Aldur, 1959-

    2016-01-01

    Varasemast laevaehitusest Läänemere ida- ja kirderannikul. Laevaehitusest Läänemere idaosas 1670. aastatest 1770. aastateni. Harderite laevatehasest Pärnus. Laevaehitusest Eestimaa kubermangus 18. sajandi lõpus ja 19. sajandi alguses. Christoph Friedrich Schmidti laevaehitusest Kuressaares. Majandusliku madalseisu ajal Pärnus ehitatud laevadest. Kuramaa mõjust laevaehituse kujunemisel tööstusharuks Liivimaa kubermangudes. Harderi laevatehase taastamisest Pärnus 1840. aastatel. 1840. ja 1850. aastate laevaehitusest Eestimaal ja Narvas. Saaremaa laevaehitusest 1840. ja 1850. aastatel. Eesti soost laevameistrite ja reederite läbimurdest

  9. Euroopa hiliskeskaja suur depressioon - kas ka Liivimaal? / Ivar Leimus

    Index Scriptorium Estoniae

    Leimus, Ivar, 1953-

    2005-01-01

    Elutarbekaupade enam kui kolmekordse kallinemise tõenäoliseks põhjuseks Liivimaal 15. saj. esimesel kolmandikul võib pidada tootjate (maaelanike) arvu märgatavat vähenemist. Järgneva reaalhindade languse põhjustas arvatavasti münditoodangu järsk vähenemine alates 1440. aastatest. Pöördepunkt Liivimaa majanduses saabus 15. saj. viimasel veerandil, mil elavnes müntimine ja raha jätkus nii ehitustöödeks kui hinnaliste altarite muretsemiseks

  10. Näitused / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    1998-01-01

    Rotermanni soolaladu. "Elektrokardiogramm" (tegevuskunsti üritus); Vaal-galerii. Antoni T̉pies "Litograafiaid aastatest 1973-1995"; Mari Kadanik, Eero Barndõk, Rain Ader "Pildid" (maalid); Paldiski Põhikool. "Niemenlautta ja Hugo Simbergi fotod" (soome kunstniku fotode koopiad, pildistatud enne 1915. a.; Kullo lastegalerii. Neli uut näitust.(lastekunst); Arhitektuurimuuseum. Arnold Matteus - Tartu linna arhitekt (juubelinäitus), Alvar Aalto "Kolm objekti Eestis"; Linnagalerii Tallinnas. "Valge" (ruumi- ja moekunsti näitus); Sammas-galerii. Jüri Jegorow "Insect" (arvutigraafika); Endla Teatri palmisaal. "Muzik in der Kunst" (Tallinna kunstitudengite näitus); Eesti Rahvusraamatukogu. Õie Kütt "Uued ja vanad ehted"

  11. Arnold : esimesed 60 aastat / Joe Wuebben ja Peter McGough ; tõlkinud Sebastian Vaikmaa

    Index Scriptorium Estoniae

    Wuebben, Joe

    2009-01-01

    Sisaldab Arnold Schwarzeneggeri biograafiat, mis on esitatud kaheosalise filmistsenaariumina; artikli osa "Täielik Arnold" on kokkuvõte 30 aasta jooksul ajakirja Muscle & Fitness rubriikides "Küsi tšempionilt" ja "Küsi Arnoldilt" ilmunud Arnold Schwarzeneggeri artiklitest jõusaalis treenimisest; artikli osa "Täis elujõudu" on kokku kogutud nimekate kulturistide tsitaate Arnold Schwarzeneggerist; artikli osa "Kaaned" sisaldab kõiki Arnold Schwarzeneggeriga Weideri kulturismiajakirjade esikaani aastatest 1968-2007 ; intervjuus räägib Schwarzenegger oma edasisest karjäärist pärast kulturismiga lõpetamist 1980.

  12. ¿Y esto del género que es? Comunicación publicitaria institucional con sensibilidad de género

    Directory of Open Access Journals (Sweden)

    María Teresa Ruiz Cantero

    2012-01-01

    Full Text Available Artículo reseñado: Papí-Gálvez N; Cambronero-Saiz B. Acciones públicas de sensibilización de género. El esfuerzo de la administración regional y local en comunicación publicitaria (1999-2007. Pensar la publicidad, Vol. 5-2, pp 179-201

  13. The Conference in the Moscow Kremlin State Museums “Historical Weapons in Museums and Private Collections”

    OpenAIRE

    Sergey P. Orlenko

    2017-01-01

    In November 2016 in the Moscow Kremlin State Historical and Cultural Museum and Heritage Site in the framework of events dedicated to the 210th anniversary of the Armoury Chamber museum, an international conference “Historical weapons in museums and private collections”. This scientific forum continued the tradition of conferences held in the Moscow Kremlin Museums in 1999-2007. The participants of this forum discussed a number of priority topics for the studies of the weapon collection h...

  14. Valley of the unicorns: consumer genomics, venture capital and digital disruption

    OpenAIRE

    Hogarth, Stuart James

    2017-01-01

    Drawing on the sociology of expectations and sociology of conventions, this paper explores issues of worth and value in the bioeconomy, and the promissory character of contemporary capitalism. Arguing that the literature on biocapital has paid insufficient attention to geographical differentiation in capital accumulation strategies, this paper situates the consumer genomics firm 23andme in the entrepreneurial culture of Silicon Valley. The paper suggests that in Silicon Valley the relationshi...

  15. Energiatõhusus ja selle hind / Tõnu Mauring

    Index Scriptorium Estoniae

    Mauring, Tõnu, 1968-

    2010-01-01

    Austri arhitekti Georg W. Reinbergi raamatust "Ecological Architecture - Design, Planning, Realization" (2008). Uuringust, mis võttis kokku aastatel 2003-2008 Viini ehitatud elamute valimi andmed ning millest järeldub, et suuremate hoonete puhul võib passiivmaja maksumus olla madalenergiamajadega ühesugune. Vajadusest ehitada Eestis valmis oma näited, leidmaks, kas tõhus energia kasutamine ja inimsõbralik hoone on või ei ole konfliktis selle rajamise hinnaga

  16. President Rüütel valis võimsa Audi / Antti Oolo

    Index Scriptorium Estoniae

    Oolo, Antti, 1967-

    2002-01-01

    President Arnold Rüütli uus ametiauto on Audi A8 4,2 Lang Quattro Automat. Uue ametiauto rentimiseks loodud komisjoni kuulusid presidendi kantselei haldusdirektor Andres Suurkuusk, direktori nõunik Katrin Laaniste ja presidendi ihukaitse ülem Aivar Ridamäe. Arvamust avaldavad Ester Šank, Andres Hein, Üllar Born. Tabel: tehnilised andmed. Vt. samas: Presidendi kantselei autopark uueneb

  17. Näidendivõistluse võitis lugu buumijärgsest ängist / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2011-01-01

    Eesti teatriagentuuri näidendivõistluse võitis Piret Jaaks näidendiga "Näha roosat elevanti", teise koha said Jan Rahmani "Lell" ja Donald Tombergi "Andmed Liina Pihlapuust" ning kolmanda koha Paavo Piik "Keti lõpp" ja Kadri Noormets "GO NEO UND ROMANTIX". Lühinäidendi eripreemia läks Küllike Veedele "Puudutamata" eest

  18. Andrzej Wajda : maailm küll teadis, aga ei hoolinud / Eda Post

    Index Scriptorium Estoniae

    Post, Eda, 1983-

    2008-01-01

    Poola filmi- ja teatrilavastaja Andrzej Wajda, kes pälvis sel aastal president Toomas Hendrik Ilveselt Maarjamaa Risti III klassi teenetemärgi. Tema viimasest mängufilmist "Katõn". Lisatud andmed elu ja töö kohta. Ordenit vastu võtma A. Wajda ei tule, sest 24. veebruaril 2008 läheb ta Los Angeleses Oscarite galale, kus tema film "Katõn" on parima võõrkeelse filmi auhinna nominent

  19. Development of Azeotropic Blends to Replace TCE and nPB in Vapor Degreasing Operations

    Science.gov (United States)

    2016-12-21

    Equipment C Safety Glasses, Gloves, Apron Revision Summary; Section 1 – Remove Pharmaceutical Grade, SMC Address Change Section 3...Markets Materials Division (EMMD) will not knowingly sample, support, or sell its products for incorporation in medical and pharmaceutical products and...m3);STEL 400 ppm OEL-TURKEY :TWA 200 ppm (590 mg/m3) OEL-UNITED KINGDOM:TWA 200 ppm (590 mg/m3);S TEL 300 ppm OEL IN BULGARIA, COLOMBIA , JORDAN

  20. President Ilves : Let's Make Estonia Greater! = President Ilves : Teeme Eesti suuremaks!

    Index Scriptorium Estoniae

    2006-01-01

    Euroopa Parlamendi aseesimees Toomas Hendrik Ilves valiti Eesti uueks presidendiks 2006. aasta 23. septembril. Lisa: Toomas Hendrik Ilves (eluloolised andmed, haridus, karjäär). Vt. samas: Toomas Hendrik Ilves: More Cooperation, More Europe = Toomas Hendrik Ilves: Rohkem koostööd, rohkem Euroopat. T.H. Ilves räägib oma sõnumist Euroopale, vajadusest Euroopa Liidu ühise energia- ja julgeolekupoliitika järele, Eesti suhetest Venemaa ja USAga

  1. Уровень воды в куртнаских озерах продолжает падать / Кюлли Крийс

    Index Scriptorium Estoniae

    Крийс, Кюлли, 1961-

    2016-01-01

    Endiselt languses olevate Kurtna järvede veetaseme muutumist saab nüüd jälgida kaardirakenduse abil, mille andmed tuginevad Jaanus Terasmaa juhitud järvede töörühma tehtud regulaarsetel mõõtmistel ja mullu sügisel keskkonnaameti eestvõttel käivitunud automaatseirel. Selgitusi jagab Tallinna Ülikooli ökoloogia instituudi vanemteadur Jaanus Terasmaa

  2. Kurtna järvede veetase jätkab langemist / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2016-01-01

    Endiselt languses olevate Kurtna järvede veetaseme muutumist saab nüüd jälgida kaardirakenduse abil, mille andmed tuginevad alates 2012. aastast Jaanus Terasmaa juhitud järvede töörühma tehtud regulaarsetel mõõtmistel ja mullu sügisel keskkonnaameti eestvõttel käivitunud automaatseirel. Veetaseme languse ja uuringute kohta jagab selgitusi Tallinna Ülikooli ökoloogia instituudi vanemteadur Jaanus Terasmaa

  3. Londoni terror sundis võitlema terroristide värbamisega Euroopas / Ahto Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Ahto, 1970-

    2005-01-01

    EL-i õigus-, vabadus- ja julgeolekuvolinik Franco Frattini avaldas muret Londoni noorte muslimite pärast, kes on hakanud enesetaputerroristideks. Lisaks esitas Frattini direktiiveelnõu telefonikõnesid ning e-posti puudutavate andmetele kohustusliku säilitusaja kehtestamiseks, Eesti aga ei nõustu nõudega säilitada andmed vastamata kõnede kohta, pidades tekkivat lisakulu õigustamatuks

  4. Enterprising or altruistic selves? Making up research subjects in genetics research.

    Science.gov (United States)

    Tutton, Richard; Prainsack, Barbara

    2011-11-01

    The emergence of direct-to-consumer (DTC) personal genomics companies in 2007 was accompanied by considerable media attention and criticism from clinical geneticists and other health professionals, regulators, policy advisors, and ethicists. As well as offering genetic testing services, some firms are also engaged in building their own databases and conducting research with the data obtained from their customers. In this paper, we examine how one of these companies, 23andMe, is creating a certain kind of 'research subject' in opposition to that constituted in conventional forms of disease research. Drawing on debates about neoliberalism, contemporary health discourses and subjectivity, we consider two kinds of subjectivities produced through the discursive and material practices of 23andMe and UK Biobank, namely, 'enterprising' and 'altruistic' selves. We argue that the 23andMe model promotes the idea that curiosity about one's genome on the one hand, and participation in research on the other, are not only compatible but complementary aspects of being an entrepreneurial subject of contemporary health and medicine framed by the technologies of web 2.0. © 2011 The Authors. Sociology of Health & Illness © 2011 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

  5. In-hospital mortality pattern of severely injured children

    DEFF Research Database (Denmark)

    Do, Hien Quoc; Steinmetz, Jacob; Rasmussen, Lars S

    2012-01-01

    BACKGROUND: Although trauma remains a major cause of morbidity and mortality in children, less attention has been directed to this group of patients. Whilst there is considerable literature on trauma in adults, only few studies describe paediatric trauma. The aim of this study was to describe...... the mortality pattern of severely injured children admitted to a Danish level I trauma centre. METHODS: We included trauma patients aged 15 years or less, who subsequent a trauma team activation were admitted during the 9-year period 1999-2007. Data were collected prospectively for subjects who had a length...

  6. House of Cards and the Paradoxical Role of Netflix

    DEFF Research Database (Denmark)

    Nielsen, Jakob Isak

    2013-01-01

    Since the late 1990s when HBO ventured into original programming and launched its triad of Oz (1997-2003), Sex and the City (1998-2004) and The Sopranos (1999-2007) the competition within American TV series has been played out amongst three types of networks and corresponding economic models......: series commissioned by advertiser-based broadcast networks, series commissioned by subscription-based premium cable networks and series commissioned by basic cable networks that rely on a combination of subscription and advertiser funding. Each of these platforms informs the audiovisual strategy...

  7. A infuência de O Poderoso Chefão na narrativa de Família Soprano = The infuence of The Godfather in the Sopranos storytelling

    OpenAIRE

    Pires, Cristine de Andrade

    2015-01-01

    O Poderoso Chefão (The Godfather, Francis Ford Coppola, 1972) é considerado paradigma entre os filmes de máfia. Entre os seriados de tevê, Família Soprano (The Sopranos, David Chase, 1999-2007) surge como principal representante do gênero. De acordo com autores como Messenger (2002), Santopietro (2012) e Martin (2014), a presença da família Corleone, que protagonizou a trilogia mafiosa de Coppola, é marca constante durante as oito temporadas de Família Soprano. Essa presença, no entanto, não ...

  8. Interações imunocerebrais e implicações nos transtornos psiquiátricos

    OpenAIRE

    Marques,Andrea H; Cizza,Giovanni; Sternberg,Esther

    2007-01-01

    OBJETIVO: Nesta revisão será focado o papel das citocinas no sistema nervoso central e suas implicações para o quadro depressivo. Posteriormente, serão discutidos os principais achados sobre medidas de citocinas em pacientes com depressão maior. MÉTODO: Foi realizada uma pesquisa no Pubmed selecionando estudos entre 1999-2007, utilizando as seguintes palavras-chave: "depression, cytokine"; "depressive disorder, cytokine". Focou-se nos estudos de medidas de citocinas pró-inflamatórias em pacie...

  9. Do gender and personality traits (BFI-10) influence attitude towards genetic research?

    DEFF Research Database (Denmark)

    Sudzina, Frantisek

    2016-01-01

    There is a continuing trend of making genetic research commercially available. It is not only 23andme that offers various types of genetic tests anymore. People do not need to rely on doctor's opinion, they can purchase genetic testing kits and test themselves. Unfortunately, not all available te...... tests are reliable; as the case of Theranos showed recently. The paper aims to investigate if there is any impact of gender and of personality traits on attitude towards genetic research. Big Five Inventory is used to measure personality traits....

  10. Influence of percolation patterns on growth and yield of rice plants and uptake of cadmium from polluted paddy fields using soil dressing models

    OpenAIRE

    パウル, シャマル クマル; PAUL, Shyamal Kumar

    2011-01-01

    We investigated that influence of percolation patterns on growth and yield of rice plants and uptake of cadmium from polluted paddy flelds using soil dressing models. The experiment was conducted in the green house with open and closed system percolation models (M-1,M-2,M-3,M-4,MI5,M-6,MI7,M-8,M-9andM-10). Those models were consisted of stratified soil layers and two different percolation systems (open and closed system percolation) and operated by 12.5cm (M-1 to M-6),15cm (M-7 to M-8) and 20...

  11. Ringkonnakohtu otsus

    Index Scriptorium Estoniae

    2010-01-01

    Tartu ringkonnakohtu otsusest Ain Seppiku, Sulev Seppiku ja Siim Seppiku ning ajalehe Äripäev vahel. Äripäev lükkab ümber andmed, nagu oleks Seppikutel seos nn allilmaga, nn ühiskassaga ja Oleg Lvoviga. Skeem. Vastukaja artiklitele: Raidla, Peeter. Kas Keskerakonna rahal on märk küljes? // Äripäev (2007/Mar/16), lk. 12-15 ; Raidla, Peeter. Kust võis tulla Seppikute raha? // Äripäev (2007/Mar/16), lk. 14-15

  12. Ajakasutus läbi sooprisma Eestis ja Euroopas / Malle Järve

    Index Scriptorium Estoniae

    Järve, Malle, 1943-

    2003-01-01

    Eesti töötavate naiste ja meeste ajakasutuse erinevustest ning selle analüüsist Euroopa võrdluskontekstis. Statistilised andmed tuginevad Eesti Statistikaameti ajakasutuse uuringule aastate 1999-2000 kohta ning 13 Euroopa riigis aastatel 1998-2001 läbi viidud samalaadsetele uuringutele. Lisatud statistilised tabelid töötavate meeste ja naiste ajakasutuse põhistruktuuri, keskmise tasulise töö aja kohta päevas, koduste tööde ja vaba aja nädalarütmi, erinevatele kodutöödele kuluva aja ning kogutöökoormuse kohta

  13. Faster and Simpler Approximation of Stable Matchings

    Directory of Open Access Journals (Sweden)

    Katarzyna Paluch

    2014-04-01

    Full Text Available We give a 3 2 -approximation algorithm for finding stable matchings that runs in O(m time. The previous most well-known algorithm, by McDermid, has the same approximation ratio but runs in O(n3/2m time, where n denotes the number of people andm is the total length of the preference lists in a given instance. In addition, the algorithm and the analysis are much simpler. We also give the extension of the algorithm for computing stable many-to-many matchings.

  14. Arctic Ice Dynamics Joint Experiment 1975-1976. Physical Oceanography Data Report, Salinity, Temperature and Depth Data, Camp Caribou. Volume I.

    Science.gov (United States)

    1980-02-01

    triangular array from which hydrographic stations were taken (Newton and Coachman, 1973). At the main camp, current profiles to 180 m (Hunkins, 1974 b...Navigation report (Thorndike and Cheung, 1977) indicated signal reduction in the data at the inertial period due to filtering of approximately 50% and...m- q* .2 I -- O.4N0 O6=p 060 f-0 a0et- NWa00 PWm V0%0C- OVOM4eyN- CDP W-t-a lIf- 0a45= 0?- NM V0an e w0 VDMCI Z0 a .0 ... . .. . o

  15. The application of virtual prototyping methods to determine the dynamic parameters of mobile robot

    Science.gov (United States)

    Kurc, Krzysztof; Szybicki, Dariusz; Burghardt, Andrzej; Muszyńska, Magdalena

    2016-04-01

    The paper presents methods used to determine the parameters necessary to build a mathematical model of an underwater robot with a crawler drive. The parameters present in the dynamics equation will be determined by means of advanced mechatronic design tools, including: CAD/CAE software andMES modules. The virtual prototyping process is described as well as the various possible uses (design adaptability) depending on the optional accessories added to the vehicle. A mathematical model is presented to show the kinematics and dynamics of the underwater crawler robot, essential for the design stage.

  16. Galojani kogutud paberid võivad varju heita ka Sinijärvele / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2007-01-01

    Autori väitel andis Eesti Euroopa Liikumise (EEL) raamatupidaja Anna-Maria Galojanile kirjalikult teada, et mõned nõukogu esimehe Riivo Sinijärve esitatud andmed ei ole kooskõlas EEL-i tegevusega. Kiri esitati kaks päeva pärast seda, kui nõukogu oli Galojani EEL-i juhi kohalt tagasi kutsunud. Mõnedest EEL-i kulutustest enne Galojani saamist selle juhiks. R. Sinijärv põhjendab EEL-i laenuvõtmise vajadust ja Julianus Inkasso nõudeid

  17. The Powder Magazine: Historical Documentation and Architectural Maintenance, Powder Magazine Park, R.E. Bob Woodruff Lake, Montgomery, Alabama

    Science.gov (United States)

    1999-01-01

    Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302, and...m HE»ś sir :-:*■■-& ..?.% ’’tf- yfaf ■w~-~" jjgf u *Jai^BbV^HK. Al , ’\\^H -- ■-:•».•> »*-. ■ 3? ^"^*f-%-" •*iF’" it m...Commission), J.J. Page (CO-SC), Jim Dees (CO-FM), Don Graham (EN-O), Carl Kling (EN-DA), Jerry Nielson (PD-E), Jim Humphries (Contractor Representative

  18. Kolmogorov Complexity Spectrum for Use in Analysis of Uv-B Radiation Time Series

    Science.gov (United States)

    Mihailović, Dragutin T.; Malinović-Milićević, Slavica; Arsenić, Ilija; Drešković, Nusret; Bukosa, Beata

    2013-10-01

    In this paper, we have used the Kolmogorov complexity and sample entropy measures to estimate the complexity of the UV-B radiation time series in the Vojvodina region (Serbia) for the period 1990-2007. We have defined the Kolmogorov complexity spectrum and have introduced the Kolmogorov complexity spectrum highest value (KCH). We have established the UV-B radiation time series on the basis of their daily sum (dose) for seven representative places in this region using: (i) measured data, (ii) data calculated via a derived empirical formula and (iii) data obtained by a parametric UV radiation model. We have calculated the Kolmogorov complexity (KC) based on the Lempel-Ziv algorithm (LZA), KCH and sample entropy (SE) values for each time series. We have divided the period 1990-2007 into two subintervals: (i) 1990-1998 and (ii) 1999-2007 and calculated the KC, KCH and SE values for the various time series in these subintervals. It is found that during the period 1999-2007, there is a decrease in the KC, KCH and SE, compared to the period 1990-1998. This complexity loss may be attributed to (i) the increased human intervention in the post civil war period causing increase of the air pollution and (ii) the increased cloudiness due to climate changes.

  19. Keelekorralduse mõju keelekasutusele eesti keele des-vormi kasutuse põhjal 20. sajandi algusest 1970. aastateni

    Directory of Open Access Journals (Sweden)

    Helen Plado

    2017-05-01

    Full Text Available "The impact of language planning on usage on the example of the Estonian -des form from the beginning of the 20th century to the 1970s" In the article, I show on the basis of the -des converb construction to what extent and how actual language usage has been influenced by language planning and introduced rules. As the converb construction was the subject of lively discussion among Estonian language planners in the 1910s and 1920s, when rules were established that would remain prominent until the 1960s–1970s, the study is based on corpus material from the 1900s–1970s. Artiklis näitan eesti keele konverbikonstruktsiooni põhjal, kas ja kuidas on keelekorraldus keelereeglite kaudu tegelikku keelekasutust mõjutanud. Et keelekorralduses oli elavam diskussioon konverbikonstruktsiooni üle 1910.–1920. aastatel, mil koostati ka reeglid, mis jäid valitsema 1960.–1970. aastateni, siis on uurimuse aluseks korpusmaterjal 1900.–1970. aastatest. Selgub, et kunstlik keeleuuendus võetakse tarvitusse, kui seda toetab teise keeles juba olemasoleva konstruktsiooni analoogia. Nii on keelde jõudnud eksplitsiitse tegevussubjektiga des-tarind ja minevikuline des-tarind, mille kasutussagedus on siiski madal võrreldes tüüpilise implitsiitse ja olevikulise konverbikonstruktsiooniga. Marginaalsem on aga keelekorralduse mõju juhul, kui kõne all on keeles olemasoleva tarindi peensusteni minevate funktsioonide eristamine.

  20. Jet production in ep collisions at high Q{sup 2} and determination of {alpha}{sub s}

    Energy Technology Data Exchange (ETDEWEB)

    Aaron, F.D. [National Institute for Physics and Nuclear Engineering (NIPNE), Bucharest (Romania); Bucharest Univ. (Romania). Faculty of Physics; Alexa, C. [National Institute for Physics and Nuclear Engineering (NIPNE), Bucharest (Romania); Alimujiang, K. [DESY Hamburg (DE)] (and others)

    2009-03-15

    The production of jets is studied in deep-inelastic e{sup {+-}}p scattering at large negative four momentum transfer squared 150 < Q{sup 2} < 15000 GeV{sup 2} using HERA data taken in 1999-2007, corresponding to an integrated luminosity of 395 pb{sup -1}. Inclusive jet, 2-jet and 3-jet cross sections, normalised to the neutral current deep-inelastic scattering cross sections, are measured as functions of Q{sup 2}, jet transverse momentum and proton momentum fraction. The measurements are well described by perturbative QCD calculations at next-to-leading order corrected for hadronisation effects. The strong coupling as determined from these measurements is {alpha}{sub s}(M{sub Z}) = 0.1168 {+-} 0.0007 (exp.) {sup +0.0046}{sub -0.0030}(th.) {+-} 0.0016 (PDF). (orig.)

  1. The association between sports participation and athletic identity with eating pathology among college-aged males and females.

    Science.gov (United States)

    Fay, K; Economos, C; Lerner, R M; Becker, A E; Sacheck, J

    2011-06-01

    The current study examined associations among sports participation (SP), athletic identity (AI), weight status, and eating pathology, and whether these relations differed by gender. Data come from male and female first-year college students who participated in the Tufts Longitudinal Health Study (TLHS) between 1999-2007 (N=712). Relations among SP, AI, actual and perceived weight statuses, Eating Disorders Inventory (EDI) subscale scores, and indices of body shape concern and restrictive eating were examined with hierarchical ordinary least squares (OLS) regression. Associations between SP and eating pathology among females were moderated by perceived weight status. By contrast, relations between males' EDI subscales scores and SP were moderated by ethnicity, as well as by actual weight status. Our findings support that sports participation alone neither promotes nor protects against eating pathology among males and females.

  2. Designing with daylight; the relationship between daylight and health

    DEFF Research Database (Denmark)

    Hauge, Bettina

    2015-01-01

    architecture’ which focuses on how to increase the solar influx when designing and building houses (Hobday 1999, 2007). But daylight is also complicated because it is measured and valued quantitatively and qualitatively and, furthermore, has seasonal variations, creating challenges when building living areas...... aiming at as much daylight as possible through the year. Those responsible for designing and building the home, architects and engineers, rely on quantifiable ways of allowing enough daylight into buildings (or reducing too much); yet people living in the homes may have entirely different perceptions...... and the significance of daylight. This paper describes the views and significance of daylight to people in their everyday lives. Based on a qualitative research project in Denmark about the use of windows, performed from May to August 2012 among 13 families , using in-depth interviews, observations, photos...

  3. Validation of genetic predictors of late radiation-induced morbidity in prostate cancer patients

    DEFF Research Database (Denmark)

    Schack, Line M H; Petersen, Stine E; Nielsen, Steffen

    2017-01-01

    INTRODUCTION: Normal tissue morbidity sets the dose limit for radiotherapy (RT) in cancer treatment and has importance for quality of life for cancer survivors. A previous study of prostate cancer patients treated with RT generated clinical data for radiation-induced morbidity measured by anorectal...... physiological methods and validated questionnaires. Other studies have identified genetic predictors associated with late radiation-induced morbidity outcome. We have expanded biobank material aiming to validate single nucleotide polymorphisms (SNPs) and a gene expression classifier with endpoints on patient......-reported outcomes and biomechanical properties of the anorectum from our cohort matching originally published endpoints. MATERIALS AND METHODS: The present cohort of prostate cancer patients was treated with RT curative intent in 1999-2007. Nine SNPs associated with late radiation-induced morbidity were tested...

  4. Effects of Mid-Level Ethanol Blends on Conventional Vehicle Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Knoll, K.; West, B.; Huff, S.; Thomas, J.; Orban, J.; Cooper, C.

    2010-06-01

    Tests were conducted in 2008 on 16 late-model conventional vehicles (1999-2007) to determine short-term effects of mid-level ethanol blends on performance and emissions. Vehicle odometer readings ranged from 10,000 to 100,000 miles, and all vehicles conformed to federal emissions requirements for their federal certification level. The LA92 drive cycle, also known as the Unified Cycle, was used for testing because it more accurately represents real-world acceleration rates and speeds than the Federal Test Procedure. Test fuels were splash-blends of up to 20 volume percent ethanol with federal certification gasoline. Both regulated and unregulated air-toxic emissions were measured. For the 16-vehicle fleet, increasing ethanol content resulted in reductions in average composite emissions of both nonmethane hydrocarbons and carbon monoxide and increases in average emissions of ethanol and aldehydes.

  5. Warming may create substantial water supply shortages in the Colorado River basin

    Science.gov (United States)

    McCabe, G.J.; Wolock, D.M.

    2007-01-01

    The high demand for water, the recent multiyear drought (1999-2007), and projections of global warming have raised questions about the long-term sustainability of water supply in the southwestern United States. In this study, the potential effects of specific levels of atmospheric warming on water-year streamflow in the Colorado River basin are evaluated using a water-balance model, and the results are analyzed within the context of a multi-century tree-ring reconstruction (1490-1998) of streamflow for the basin. The results indicate that if future warming occurs in the basin and is not accompanied by increased precipitation, then the basin is likely to experience periods of water supply shortages more severe than those inferred from the longterm historical tree-ring reconstruction. Furthermore, the modeling results suggest that future warming would increase the likelihood of failure to meet the water allocation requirements of the Colorado River Compact.

  6. Using the sense of coherence framework as a tactical approach to communicating corrective action in crisis situations

    DEFF Research Database (Denmark)

    Simonsen, Daniel Morten; Jacobsen, Johan Martin Hjorth

    describes the motivation, that is, why it is important for the organization to handle the crisis situation and make the corrective action (Antonovsky, 2000). This paper argues that, if the organization communicates these three variables to its external stakeholders during a crisis, the communication......By combining attribution theory with crisis types, Coombs developed a theory of Situational Crisis Communication (SCCT) that recommends which crisis response strategy is appropriate for which crisis (Coombs, 1999; 2007; 2012). The seven response strategies presented in SCCT have been tested...... empirically; however, there still is a need for empirical contributions on the tactical level where the Crisis Communication Message (CCM) is developed, as argued here: “SCCT tries to answer the question of when to use different crisis responses, but it does not help researchers address the question of how...

  7. Seasonal variation in the acute presentation of urinary calculi over 8 years in Auckland, New Zealand.

    Science.gov (United States)

    Lo, Sum Sum; Johnston, Richard; Al Sameraaii, Ahmed; Metcalf, Patricia A; Rice, Michael L; Masters, Jonathan G

    2010-07-01

    Symptom prevalence (retrospective cohort) Level of Evidence 2b. To determine the incidence of acute presentation of urinary calculi (UC) in Auckland, New Zealand, during the period 1999-2007, and whether there was any significant seasonal variation. The details of all UC within the population presenting acutely to public hospitals in Auckland between 1999 and 2007 were collected using clinical coding searches International Classification of Disease 10th revision (Australian Modification) N132 and N20. Climatic variables for the Auckland region were obtained from the National Institute of Water and Atmospheric Research, New Zealand. The mean atmospheric temperature, hours of sunshine and humidity data were calculated monthly for this period. During the study there were 7668 acute presentations of UC in the Auckland region. A Poisson regression model showed that the number of presentations was significantly related to temperature (P Auckland, New Zealand, varies significantly with temperature and hours of sunshine. Humidity was not a significant factor.

  8. Inflation Targeting and Exchange Rate Management in Korea

    Directory of Open Access Journals (Sweden)

    Won-Am Park

    2008-06-01

    Full Text Available This paper investigates the experience of inflation targeting in Korea with an emphasis on exchange rate management. The Korean call rate responded to not only expected inflation, but also to output gap and changes in the real effective exchange rate of the Korean won, when we estimated the call rate reaction function over the period of 1999-2007. It was found that the call rate responded to changes in real effective exchange rate more than it did to expected inflation. We also examined whether Korean inflation targeting was actually centered on the exchange rate by estimating the Singaporean style of exchange rate reaction function. It was found that Korean monetary policy was not exchange-rate- centered, since the nominal effective exchange rate of the Korean won responded modestly to inflation and output gap, far less than did the Singaporean dollar.

  9. Jet Production in ep Collisions at High $Q^2$ and Determination of $\\alpha_s$

    CERN Document Server

    Aaron, F.D.; Alimujiang, K.; Andreev, V.; Antunovic, B.; Asmone, A.; Backovic, S.; Baghdasaryan, A.; Barrelet, E.; Bartel, W.; Begzsuren, K.; Belousov, A.; Bizot, J.C.; Boudry, V.; Bozovic-Jelisavcic, I.; Bracinik, J.; Brandt, G.; Brinkmann, M.; Brisson, V.; Bruncko, D.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Cantun Avila, K.B.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Cholewa, A.; Contreras, J.G.; Coughlan, J.A.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Daum, K.; Deak, M.; de Boer, Y.; Delcourt, B.; Del Degan, M.; Delvax, J.; De Roeck, A.; De Wolf, E.A.; Diaconu, C.; Dodonov, V.; Dossanov, A.; Dubak, A.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eliseev, A.; Elsen, E.; Falkiewicz, A.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Fischer, D.-J.; Fleischer, M.; Fomenko, A.; Gabathuler, E.; Gayler, J.; Ghazaryan, Samvel; Glazov, A.; Glushkov, I.; Goerlich, L.; Gogitidze, N.; Gouzevitch, M.; Grab, C.; Greenshaw, T.; Grell, B.R.; Grindhammer, G.; Habib, S.; Haidt, D.; Helebrant, C.; Henderson, R.C.W.; Hennekemper, E.; Henschel, H.; Herbst, M.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hreus, T.; Jacquet, M.; Janssen, M.E.; Janssen, X.; Jemanov, V.; Jonsson, L.; Jung, Andreas Werner; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I.R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Kluge, T.; Knutsson, A.; Kogler, R.; Korbel, V.; Kostka, P.; Kraemer, M.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Kruger, K.; Kutak, K.; Landon, M.P.J.; Lange, W.; Lastovicka-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Li, G.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lytkin, L.; Makankine, A.; Malinovski, E.; Marage, P.; Marti, Ll.; Martyn, H.-U.; Maxfield, S.J.; Mehta, A.; Meyer, A.B.; Meyer, H.; Meyer, H.; Meyer, J.; Michels, V.; Mikocki, S.; Milcewicz-Mika, I.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, Matthias Ulrich; Mudrinic, M.; Muller, K.; Murin, P.; Naroska, B.; Naumann, Th.; Newman, P.R.; Niebuhr, C.; Nikiforov, A.; Nowak, G.; Nowak, K.; Nozicka, M.; Olivier, B.; Olsson, J.E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Pandurovic, M.; Papadopoulou, Th.; Pascaud, C.; Patel, G.D.; Pejchal, O.; Perez, E.; Petrukhin, A.; Picuric, I.; Piec, S.; Pitzl, D.; Placakyte, R.; Pokorny, B.; Polifka, R.; Povh, B.; Preda, T.; Radescu, V.; Rahmat, A.J.; Raicevic, N.; Raspiareza, A.; Ravdandorj, T.; Reimer, P.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rotaru, M.; Ruiz Tabasco, J.E.; Rurikova, Z.; Rusakov, S.; Salek, D.; Sankey, D.P.C.; Sauter, M.; Sauvan, E.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.-C.; Sefkow, F.; Shaw-West, R.N.; Sheviakov, I.; Shtarkov, L.N.; Shushkevich, S.; Sloan, T.; Smiljanic, Ivan; Soloviev, Y.; Sopicki, P.; South, D.; Spaskov, V.; Specka, Arnd E.; Staykova, Z.; Steder, M.; Stella, B.; Stoicea, G.; Straumann, U.; Sunar, D.; Sykora, T.; Tchoulakov, V.; Thompson, G.; Thompson, P.D.; Toll, T.; Tomasz, F.; Tran, T.H.; Traynor, D.; Trinh, T.N.; Truol, P.; Tsakov, I.; Tseepeldorj, B.; Turnau, J.; Urban, K.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Vinokurova, S.; Volchinski, V.; von den Driesch, M.; Wegener, D.; Wissing, Ch.; Wunsch, E.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.; Zus, R.

    2010-01-01

    The production of jets is studied in deep-inelastic ep scattering at large negative four momentum transfer squared 1501999-2007, corresponding to an integrated luminosity of 395 pb^-1. Inclusive jet, 2-jet and 3-jet cross sections, normalised to the neutral current deep-inelastic scattering cross sections, are measured as functions of Q^2, jet transverse momentum and proton momentum fraction. The measurements are well described by perturbative QCD calculations at next-to-leading order corrected for hadronisation effects. The strong coupling as determined from these measurements is alpha_s(M_Z) = 0.1168 +/-0.0007 (exp.) +0.0046/-0.0030 (th.) +/-0.0016(pdf).

  10. Jet production in ep collisions at high Q2 and determination of αs

    International Nuclear Information System (INIS)

    Aaron, F.D.; Alexa, C.; Preda, T.; Rotaru, M.; Stoicea, G.; Zus, R.; Alimujiang, K.; Antunovic, B.; Bartel, W.; Brandt, G.; Campbell, A.J.; Cholewa, A.; Deak, M.; Boer, Y. de; Roeck, A. de; Eckerlin, G.; Elsen, E.; Felst, R.; Fischer, D.J.; Fleischer, M.; Gayler, J.; Glazov, A.; Gouzevitch, M.; Grell, B.R.; Haidt, D.; Helebrant, C.; Janssen, M.E.; Jung, H.; Katzy, J.; Kleinwort, C.; Knutsson, A.; Korbel, V.; Kraemer, M.; Krastev, K.; Kutak, K.; Levonian, S.; List, J.; Marti, L.; Meyer, A.B.; Meyer, H.; Meyer, J.; Michels, V.; Niebuhr, C.; Nikiforov, A.; Nozicka, M.; Olsson, J.E.; Panagoulias, I.; Papadopoulou, T.; Pitzl, D.; Placakyte, R.; Radescu, V.; Rurikova, Z.; Schmitt, S.; Sefkow, F.; Staykova, Z.; Steder, M.; Vargas Trevino, A.; Vinokurova, S.; Driesch, M. von den; Wissing, C.; Wuensch, E.; Andreev, V.; Belousov, A.; Eliseev, A.; Fomenko, A.; Gogitidze, N.; Lebedev, A.; Loktionova, N.; Malinovski, E.; Rusakov, S.; Sheviakov, I.; Shtarkov, L.N.; Soloviev, Y.; Vazdik, Y.; Asmone, A.; Stella, B.; Backovic, S.; Dubak, A.; Lastovicka-Medin, G.; Picuric, I.; Raicevic, N.; Baghdasaryan, A.; Ghazaryan, S.; Volchinski, V.; Zohrabyan, H.; Barrelet, E.; Begzsuren, K.; Ravdandorj, T.; Tseepeldorj, B.; Bizot, J.C.; Brisson, V.; Delcourt, B.; Jacquet, M.; Li, G.; Pascaud, C.; Tran, T.H.; Zhang, Z.; Zomer, F.; Boudry, V.; Moreau, F.; Specka, A.; Bozovic-Jelisavcic, I.; Mudrinic, M.; Pandurovic, M.; Smiljanic, I.; Bracinik, J.; Faulkner, P.J.W.; Kenyon, I.R.; Newman, P.R.; Shaw-West, R.N.; Thompson, P.D.; Brinkmann, M.; Habib, S.; Jemanov, V.; Lipka, K.; List, B.; Naroska, B.; Pokorny, B.; Toll, T.; Bruncko, D.; Cerny, V.; Ferencei, J.; Murin, P.; Tomasz, F.; Bunyatyan, A.; Buschhorn, G.; Chekelian, V.; Dossanov, A.; Grindhammer, G.; Kiesling, C.; Kogler, R.; Liptaj, A.; Olivier, B.; Raspiareza, A.; Shushkevich, S.; Bystritskaya, L.; Efremenko, V.; Fedotov, A.; Kropivnitskaya, A.; Lubimov, V.; Ozerov, D.; Petrukhin, A.; Rostovtsev, A.; Zhokin, A.; Cantun Avila, K.B.; Contreras, J.G.; Ruiz Tabasco, J.E.; Cassol-Brunner, F.; Diaconu, C.; Hoffmann, D.; Sauvan, E.; Trinh, T.N.; Vallee, C.; Cerny, K.; Pejchal, O.; Polifka, R.; Salek, D.; Valkarova, A.; Zacek, J.; Coughlan, J.A.; Morris, J.V.; Sankey, D.P.C.; Cozzika, G.; Feltesse, J.; Perez, E.; Schoeffel, L.; Cvach, J.; Reimer, P.; Zalesak, J.; Dainton, J.B.; Gabathuler, E.; Greenshaw, T.; Klein, M.; Kluge, T.; Kretzschmar, J.; Laycock, P.; Maxfield, S.J.; Mehta, A.; Patel, G.D.; Rahmat, A.J.; Daum, K.; Meyer, H.; Del Degan, M.; Grab, C.; Leibenguth, G.; Sauter, M.; Zimmermann, T.; Delvax, J.; Wolf, E.A. de; Favart, L.; Hreus, T.; Janssen, X.; Marage, P.; Mozer, M.U.; Roland, B.; Roosen, R.; Sunar, D.; Sykora, T.; Mechelen, P. van; Dodonov, V.; Lytkin, L.; Povh, B.; Egli, S.; Hildebrandt, M.; Horisberger, R.; Falkiewicz, A.; Goerlich, L.; Mikocki, S.; Milcewicz-Mika, I.; Nowak, G.; Sopicki, P.; Turnau, J.; Glushkov, I.; Henschel, H.; Hiller, K.H.; Kostka, P.; Lange, W.; Naumann, T.; Piec, S.; Henderson, R.C.W.; Sloan, T.; Hennekemper, E.; Herbst, M.; Jung, A.W.; Krueger, K.; Lendermann, V.; Schultz-Coulon, H.C.; Urban, K.; Herrera, G.; Lopez-Fernandez, R.; Joensson, L.; Osman, S.; Kapichine, M.; Makankine, A.; Morozov, A.; Palichik, V.; Spaskov, V.; Tchoulakov, V.; Landon, M.P.J.; Rizvi, E.; Thompson, G.; Traynor, D.; Martyn, H.U.; Mueller, K.; Nowak, K.; Robmann, P.; Schmitz, C.; Straumann, U.; Truoel, P.; Schoening, A.; South, D.; Wegener, D.; Tsakov, I.

    2010-01-01

    The production of jets is studied in deep-inelastic e ± p scattering at large negative four momentum transfer squared 150 2 2 using HERA data taken in 1999-2007, corresponding to an integrated luminosity of 395 pb -1 . Inclusive jet, 2-jet and 3-jet cross sections, normalised to the neutral current deep-inelastic scattering cross sections, are measured as functions of Q 2 , jet transverse momentum and proton momentum fraction. The measurements are well described by perturbative QCD calculations at next-to-leading order corrected for hadronisation effects. The strong coupling as determined from these measurements is α s (M Z )=0.1168±0.0007(exp.) +0.0046 -0.0030 (th.)±0.0016 (PDF). (orig.)

  11. Planeeringut ei saadud 8 päevaga

    Index Scriptorium Estoniae

    2010-01-01

    Tartu Ringkonnakohtu otsusest Ain Seppiku, Sulev Seppiku ja Siim Seppiku ning ajalehe Äripäev vahel. Äripäev lükkab ümber andmed selle kohta, nagu oleks nn Antennideväljaku krundi detailplaneering kehtestatud 8 päevaga. Vastukaja artiklitele: Soe, Ralf-Martin. Sulev Seppik tegi Viimsis imet. // Äripäev (2007/Mar/1), lk. 4-5 ; Arumäe, Urmas. Viimsi võim ei tegele maaäriga. // Äripäev (2007/Mar/13), lk. 27 ; Soe, Ralf-Martin. Viimsi võtmeisikute tehingutel kahtlane maik. // Äripäev (2007/Mar/23), lk. 12-13

  12. Induction of genetic variability in oat

    Directory of Open Access Journals (Sweden)

    Jefferson Luis Meirelles Coimbra

    2007-01-01

    Full Text Available Genetic variability in plants can be maximized through techniques of induction to make selection of genotypeswith improved adaptation to cultivation conditions possible. For oat, these techniques are important for a sustainabledevelopment through plant breeding programs in southern Brazil. The effects of mutagens (one physical: 60Co gamma raysand two chemical agents: ethyl - methanesulfonate and methyl-methanesulfonate were compared in the segregating M2 andM3 generations derived from artificial hybridization and induced mutation to compare mechanisms of widening the geneticvariability of oat. The methodologies increased the genetic variability in the trait vegetative cycle effectively, by either increasingor reducing the number of days from emergence to full heading; both can be applied in oat breeding programs.

  13. Design, methods, and participant characteristics of the Impact of Personal Genomics (PGen) Study, a prospective cohort study of direct-to-consumer personal genomic testing customers.

    Science.gov (United States)

    Carere, Deanna Alexis; Couper, Mick P; Crawford, Scott D; Kalia, Sarah S; Duggan, Jake R; Moreno, Tanya A; Mountain, Joanna L; Roberts, J Scott; Green, Robert C

    2014-01-01

    Designed in collaboration with 23andMe and Pathway Genomics, the Impact of Personal Genomics (PGen) Study serves as a model for academic-industry partnership and provides a longitudinal dataset for studying psychosocial, behavioral, and health outcomes related to direct-to-consumer personal genomic testing (PGT). Web-based surveys administered at three time points, and linked to individual-level PGT results, provide data on 1,464 PGT customers, of which 71% completed each follow-up survey and 64% completed all three surveys. The cohort includes 15.7% individuals of non-white ethnicity, and encompasses a range of income, education, and health levels. Over 90% of participants agreed to re-contact for future research.

  14. Burial of Zostera marina seeds in sediment inhabited by three polychaetes: laboratory and field studies

    DEFF Research Database (Denmark)

    Delefosse, Matthieu; Kristensen, Erik

    2012-01-01

    passively by sedimentation or actively through sediment reworking by benthic fauna.We evaluated the effect of three polychaetes on the burial rate and depth of eelgrass seeds. Burial was first measured in controlled laboratory experiments using different densities of Nereis (Hediste) diversicolor (400......–3200 ind m −2), Arenicola marina (20–80 ind m−2), and the invasive Marenzelleria viridis (400–1600 ind m −2). The obtained results were subsequently compared with burial rates of seed mimics in experimental field plots (1m2) dominated by the respective polychaetes. High recovery of seeds in the laboratory....... At their highest abundance, A. marina andM. viridis buried seeds to amedian depth of 6.7 cmand 0.5 cm, respectively, after amonth. The burial efficiency and depth of these species were, in contrast to N. diversicolor, dependent on animal abundance. Only 2% of seed mimics casted in the field plots were recovered...

  15. DINAMISASI TRADISI ISLAM DI ERA GLOBALISASI: Studi atas Tradisi Keagamaan Kampung Jawa Tondano

    Directory of Open Access Journals (Sweden)

    Yusno Abdullah Otta

    2016-09-01

    Full Text Available There are signifiant relationship between modernization andm religion in the modernization and globalization era. In the context of Indonesia, religion, the teachings and traditions, preserved as a fundamental basis of morality to inflence the flw of modernization. Indonesian society, in general, divided into two groups of “modernist” and “traditional”. This grouping occurs because, from a historical perspective, the existence of Islam in Indonesia is experiencing a collision with various forms of local syncretic and, also, with Western civilization, especially, in the period of colonialism, the Christian religion, as happened in the village of Tondano Java, in particular, and other areas in Indonesia, in general. The result of research shows that all the tradition in this Tondano Javanese village today is still carried out consistently by the citizens. Flow of modernization and globalization were not many signifiant impacts for the implementation of these various religious traditions.

  16. The contribution of reduction in malaria as a cause of rapid decline of under-five mortality: evidence from the Rufiji Health and Demographic Surveillance System (HDSS) in rural Tanzania.

    Science.gov (United States)

    Kanté, Almamy M; Nathan, Rose; Helleringer, Stéphane; Sigilbert, Mrema; Levira, Francis; Masanja, Honorati; de Savigny, Don; Abdulla, Salim; Phillips, James F

    2014-05-10

    Under-five mortality has been declining rapidly in a number of sub-Saharan African settings. Malaria-related mortality is known to be a major component of childhood causes of death and malaria remains a major focus of health interventions. The paper explored the contribution of malaria relative to other specific causes of under-five deaths to these trends. This paper uses longitudinal demographic surveillance data to examine trends and causes of death of under-five mortality in Rufiji, whose population has been followed for over nine years (1999-2007). Causes of death, determined by the verbal autopsy technique, are analysed with Arriaga's decomposition method to assess the contribution of declining malaria-related mortality relative to other causes of death as explaining a rapid decline in overall childhood mortality. Over the 1999-2007 period, under-five mortality rate in Rufiji declined by 54.3%, from 33.3 to 15.2 per 1,000 person-years. If this trend is sustained, Rufiji will be a locality that achieves MDG4 target. Although hypotrophy at birth remained the leading cause of death for neonates, malaria remains as the leading cause of death for post-neonates followed by pneumonia. However, declines in malaria death rates accounted for 49.9% of the observed under-five mortality decline while all perinatal causes accounted for only 19.9%. To achieve MDG 4 in malaria endemic settings, health programmes should continue efforts to reduce malaria mortality and more efforts are also needed to improve newborn survival.

  17. Concurrent subacute exposure to arsenic through drinking water and malathion via diet in male rats: effects on hepatic drug-metabolizing enzymes

    Energy Technology Data Exchange (ETDEWEB)

    Naraharisetti, Suresh Babu [Indian Veterinary Research Institute, Division of Pharmacology and Toxicology, Izatnagar, Uttar Pradesh (India); University of Washington, Department of Medicinal Chemistry, Seattle, WA (United States); Aggarwal, Manoj [Indian Veterinary Research Institute, Division of Pharmacology and Toxicology, Izatnagar, Uttar Pradesh (India); Institut fuer Arbeitsphysiologie an der Universitaet Dortmund, Dortmund (Germany); Sarkar, S.N.; Malik, J.K. [Indian Veterinary Research Institute, Division of Pharmacology and Toxicology, Izatnagar, Uttar Pradesh (India)

    2008-08-15

    Arsenic is a known global groundwater contaminant, while malathion is one of the most widely used pesticides in agriculture and public health practices in the world. Here, we investigated whether repeated exposure to arsenic at the groundwater contamination levels and to malathion at sublethal levels exerts adverse effects on the hepatic drug-metabolizing system in rats, and whether concurrent exposure is more hazardous than the single agent. Male Wistar rats were exposed daily to 4 or 40 ppm of arsenic via drinking water, 50 or 500 ppm of malathion-mixed feed and in a similar fashion co-exposed to 4 ppm of arsenic and 50 ppm of malathion or 40 ppm of arsenic and 500 ppm of malathion for 28 days. At term, toxicity was assessed by evaluating changes in body weight, liver weight, levels of cytochrome P{sub 450} (CYP), cytochrome b{sub 5} and microsomal and cytosolic proteins, and activities of aminopyrine-N-demethylase (ANDM), aniline-P-hydroxylase (APH), glutathione-S-transferase (GST) and uridine diphosphate glucuronosyltransferase (UGT) in liver. Arsenic and malathion alone did not alter body weight and liver weight, but these were significantly decreased in both the co-exposed groups. These treatments decreased the activities of ANDM and APH and the levels of liver microsomal and cytosolic proteins, increased GST activity and had no effect on UGT activity. The effects of exposure to low-dose and high-dose combinations on the activities of either phase I or phase II drug-metabolizing enzymes and protein content were mostly similar to that produced by the respective low and high dose of either arsenic or malathion, except APH activity. The effect of arsenic (40 ppm) on APH activity was partially, but significantly, inhibited by malathion (500 ppm). Results indicate that the body or liver weights and the biochemical parameters were differentially affected in male rats following concurrent subacute exposure to arsenic and malathion, with the co-exposure appearing

  18. Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing

    Science.gov (United States)

    Dijamco, Cheri; Kiefer, Amy K.; Eriksson, Nicholas; Moiseff, Bianca; Tung, Joyce Y.; Mountain, Joanna L.

    2013-01-01

    Background. Inherited BRCA gene mutations convey a high risk for breast and ovarian cancer, but current guidelines limit BRCA mutation testing to women with early-onset cancer and relatives of mutation-positive cases. Benefits and risks of providing this information directly to consumers are unknown. Methods. To assess and quantify emotional and behavioral reactions of consumers to their 23andMe Personal Genome Service® report of three BRCA mutations that are common in Ashkenazi Jews, we invited all 136 BRCA1 and BRCA2 mutation-positive individuals in the 23andMe customer database who had chosen to view their BRCA reports to participate in this IRB-approved study. We also invited 160 mutation-negative customers who were matched for age, sex and ancestry. Semi-structured phone interviews were completed for 32 mutation carriers, 16 women and 16 men, and 31 non-carriers. Questions addressed personal and family history of cancer, decision and timing of viewing the BRCA report, recollection of the result, emotional responses, perception of personal cancer risk, information sharing, and actions taken or planned. Results. Eleven women and 14 men had received the unexpected result that they are carriers of a BRCA1 185delAG or 5382insC, or BRCA2 6174delT mutation. None of them reported extreme anxiety and four experienced moderate anxiety that was transitory. Remarkably, five women and six men described their response as neutral. Most carrier women sought medical advice and four underwent risk-reducing procedures after confirmatory mutation testing. Male carriers realized that their test results implied genetic risk for female relatives, and several of them felt considerably burdened by this fact. Sharing mutation information with family members led to screening of at least 30 relatives and identification of 13 additional carriers. Non-carriers did not report inappropriate actions, such as foregoing cancer screening. All but one of the 32 mutation-positive participants

  19. Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing.

    Science.gov (United States)

    Francke, Uta; Dijamco, Cheri; Kiefer, Amy K; Eriksson, Nicholas; Moiseff, Bianca; Tung, Joyce Y; Mountain, Joanna L

    2013-01-01

    Background. Inherited BRCA gene mutations convey a high risk for breast and ovarian cancer, but current guidelines limit BRCA mutation testing to women with early-onset cancer and relatives of mutation-positive cases. Benefits and risks of providing this information directly to consumers are unknown. Methods. To assess and quantify emotional and behavioral reactions of consumers to their 23andMe Personal Genome Service(®) report of three BRCA mutations that are common in Ashkenazi Jews, we invited all 136 BRCA1 and BRCA2 mutation-positive individuals in the 23andMe customer database who had chosen to view their BRCA reports to participate in this IRB-approved study. We also invited 160 mutation-negative customers who were matched for age, sex and ancestry. Semi-structured phone interviews were completed for 32 mutation carriers, 16 women and 16 men, and 31 non-carriers. Questions addressed personal and family history of cancer, decision and timing of viewing the BRCA report, recollection of the result, emotional responses, perception of personal cancer risk, information sharing, and actions taken or planned. Results. Eleven women and 14 men had received the unexpected result that they are carriers of a BRCA1 185delAG or 5382insC, or BRCA2 6174delT mutation. None of them reported extreme anxiety and four experienced moderate anxiety that was transitory. Remarkably, five women and six men described their response as neutral. Most carrier women sought medical advice and four underwent risk-reducing procedures after confirmatory mutation testing. Male carriers realized that their test results implied genetic risk for female relatives, and several of them felt considerably burdened by this fact. Sharing mutation information with family members led to screening of at least 30 relatives and identification of 13 additional carriers. Non-carriers did not report inappropriate actions, such as foregoing cancer screening. All but one of the 32 mutation-positive participants

  20. Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing

    Directory of Open Access Journals (Sweden)

    Uta Francke

    2013-02-01

    Full Text Available Background. Inherited BRCA gene mutations convey a high risk for breast and ovarian cancer, but current guidelines limit BRCA mutation testing to women with early-onset cancer and relatives of mutation-positive cases. Benefits and risks of providing this information directly to consumers are unknown.Methods. To assess and quantify emotional and behavioral reactions of consumers to their 23andMe Personal Genome Service® report of three BRCA mutations that are common in Ashkenazi Jews, we invited all 136 BRCA1 and BRCA2 mutation-positive individuals in the 23andMe customer database who had chosen to view their BRCA reports to participate in this IRB-approved study. We also invited 160 mutation-negative customers who were matched for age, sex and ancestry. Semi-structured phone interviews were completed for 32 mutation carriers, 16 women and 16 men, and 31 non-carriers. Questions addressed personal and family history of cancer, decision and timing of viewing the BRCA report, recollection of the result, emotional responses, perception of personal cancer risk, information sharing, and actions taken or planned.Results. Eleven women and 14 men had received the unexpected result that they are carriers of a BRCA1 185delAG or 5382insC, or BRCA2 6174delT mutation. None of them reported extreme anxiety and four experienced moderate anxiety that was transitory. Remarkably, five women and six men described their response as neutral. Most carrier women sought medical advice and four underwent risk-reducing procedures after confirmatory mutation testing. Male carriers realized that their test results implied genetic risk for female relatives, and several of them felt considerably burdened by this fact. Sharing mutation information with family members led to screening of at least 30 relatives and identification of 13 additional carriers. Non-carriers did not report inappropriate actions, such as foregoing cancer screening. All but one of the 32 mutation

  1. An online english course using a task-based language teaching: the teacher as an agent of choice

    Directory of Open Access Journals (Sweden)

    Denise Elaine Emidio

    2016-10-01

    Full Text Available Since the advent of the new technologies, the language teaching came across to a virtual learning environment. In an attempt to consider the principles of the communicative approach (ALMEIDA FILHO, 2002, 2005, 2012 and the task-based language teaching (TBLT (SKEHAN, 1996; XAVIER 1999, 2007; BARBIRATO 1999, 2005 an online English course was offered in the Moodle platform to students of technical, technological and Undergraduate courses from a Federal institution of technology. The theme chosen for the course was Inventors and Inventions and the thematic units contemplated aspects of Nikola Tesla’s and Leonardo da Vinci’s lives and inventions. The purpose of this article, therefore, is to present and discuss results derived from a doctoral research analyzing the teacher’s role in the preparation of thematic material based on tasks for the online English course in the Moodle. The data analysis pointed out to the very important role of the teacher in the challenges and choices along the process of the material elaboration.

  2. Type of contraception method used at last intercourse and associations with health risk behaviors among US adolescents.

    Science.gov (United States)

    Cavazos-Rehg, Patricia A; Krauss, Melissa J; Spitznagel, Edward L; Schootman, Mario; Peipert, Jeffrey F; Cottler, Linda B; Bierut, Laura Jean

    2010-12-01

    This study was conducted to examine associations with contraception methods used at last sexual intercourse among US adolescents. Data consisted of sexually active adolescents (9th-12th grade, weighted n=24,638) from the 1999-2007 Youth Risk Behavior Surveillance System (YRBSS). We performed multinomial multivariable logistic regression analyses with condom users at last sexual intercourse as the reference group. Males who used alcohol, cigarettes, marijuana and cocaine were more likely to use no method/unsure of method (OR=2.4, CI=1.7-3.4) or rely on withdrawal (OR=2.6, CI=1.5-4.3). Females with six or more sexual partners were more likely to rely on withdrawal (OR=2.9, CI=2.1-3.9) or contraception methods that offer no STI protection [i.e., birth control pills: OR=1.9, CI=1.4-2.5; and depot medroxyprogesterone acetate (DMPA, marketed as Depo-Provera): OR=2.6, CI=1.6-4.2]. Earlier age of sexual debut was also associated with nonuse. Prevention efforts should focus on at-risk adolescents including substance-using males, females with six or more sexual partners, and those who initiate sexual intercourse at an early age. Copyright © 2010 Elsevier Inc. All rights reserved.

  3. Convergence, Crisis and Unemployment in Europe: The Need for Innovative Policies

    Directory of Open Access Journals (Sweden)

    Enrico Marelli

    2015-12-01

    Full Text Available The paper reviews the double crisis that affected the euro area in the recent period. The focal point is that the austerity measures that have been undertaken in the area, especially in the peripheral countries hurt by the sovereign debt crisis, have not only caused a deep recession but are likely to lead to stagnation and persistent unemployment. In the first part of the paper, original weaknesses in the construction of the monetary union are examined, the emphasis being placed on nominal convergence criteria without taking into account the need for real convergence. This analysis is corroborated by some econometric investigations based on sigma and beta convergence for different macroeconomic variables, distinguishing between the pre-crisis period, 1999-2007, and the recent 2008-2013 period. The empirical section continues with a discussion of recent macroeconomic trends focusing on unemployment: it stresses that the deep and prolonged recession can be defeated only by adequate demand management policies. The next section explains how the excessive austerity policies recently carried out have also been caused by wrong assumptions about the size of the fiscal multipliers. The final policy section emphasizes three aspects: (i the radical reforms, at the European level, necessary if the monetary union is to survive; (ii the changes in macroeconomic policies required to put an end to the present stagnation; (iii the different and innovative policies needed to fight the high level of unemployment (especially youth unemployment.

  4. Determinants of exercise capacity in school-aged esophageal atresia patients.

    Science.gov (United States)

    Toussaint-Duyster, Leontien C C; van der Cammen-van Zijp, Monique H M; Spoel, Marjolein; Lam, Mhanfei; Wijnen, Rene M H; de Jongste, Johan C; Tibboel, Dick; van Rosmalen, Joost; IJsselstijn, Hanneke

    2017-09-01

    Data on long-term outcome of exercise capacity in school-aged children with esophageal atresia (EA) are scarce. We evaluated maximal exercise capacity and its relation to lung function. Moreover, we studied other possible determinants of exercise capacity and lung function. Exercise capacity of 63 children with EA born 1999-2007 was evaluated at the age of 8 years with the Bruce-protocol. Dynamic and static lung volumes, bronchodilator response and diffusion capacity were measured. Furthermore, perinatal characteristics, hospital admissions for lower respiratory tract infections (RTIs), RTIs treated with antibiotics in the past year, symptoms of gastroesophageal reflux, weight-for-height, and sports participation were evaluated as other potential determinants. Exercise capacity was significantly below normal: mean (SD) SDS -0.91 (0.97); P Exercise capacity was positively associated with total lung capacity and negatively with SDS weight-for-height. Spirometric parameters were negatively associated with congenital cardiac malformation, duration of ventilation, and persistent respiratory morbidity. Eight-year-old children with EA had reduced exercise capacity which was only associated with the reduction in TLC he and higher SDS weight-for-height. We speculate that diminished physical activity with recurrent respiratory tract infections may also play a role in reduced exercise capacity. This should be subject to further research to optimize appropriate intervention. © 2017 Wiley Periodicals, Inc.

  5. Molecular epidemiology of HIV-1 clades in Southern Brazil

    Directory of Open Access Journals (Sweden)

    Sonia Mara Raboni

    2010-12-01

    Full Text Available Human immunodeficiency virus (HIV clades B and C account for more than 60% of the HIV-1 infections worldwide. In this paper, we describe the profiles of patients infected with subtypes of HIV-1 from the state of Paraná, Southern Brazil, and correlate them with demographic and epidemiological findings. A retrospective analysis of HIV cases reported from 1999-2007 was also performed. Data from 293 patients were reviewed and 245 were older than 13 (58% female. The distribution of clades was as follows: B 140 (57%, C 67 (23%, F 24 (10% and mosaic or unique recombinant forms (URFs 24 (10%. Of the 48 patients younger than 13 years of age (62.5% male, vertical transmission occurred in 46 and the distribution of clades was as follows: B 14 (29%, C 24 (50%, F 7 (15% and URFs 6 (13%. There was no significant difference in mortality between HIV-1 subtypes. In both groups, patients infected with clade C tended to have higher rates of injection drug use exposure risk.

  6. Can environmental and socioeconomic factors explain the recent emergence of Rift Valley fever in Yemen, 2000-2001?

    Science.gov (United States)

    Abdo-Salem, Shaif; Tran, Annelise; Grosbois, Vladimir; Gerbier, Guillaume; Al-Qadasi, Mansoor; Saeed, Khalid; Etter, Eric; Thiry, Etienne; Roger, François; Chevalier, Véronique

    2011-06-01

    Rift Valley fever (RVF) is a major vector-borne zoonosis first identified on the African continent in the early 1900s. In 2000, RVF was reported for the first time in Yemen. In this study, we provide a descriptive analysis of the period 1999-2007 in Yemen, taking into account the environmental and socioeconomic factors likely to have been involved in the emergence of RVF in the country. We characterize each year in the study period by the environmental conditions (linked to vegetation indexes), the festival calendar, and economic data. We then use a principal component analysis to synthesize the different variables, assess whether the year 2000 was atypical compared with other years in the study period, and, if that was the case, in what respect. Our results show that 2000 presented above-normal vegetation index values, which reflect important precipitation, for both the two rainy seasons (the first between March and May; the second between July and October). These environmental conditions, ones favorable to mosquito vector populations, coincided that year with a late (March) starting date of the Eid al-Kabeer festival, which corresponds to a period with high host (cattle, sheep, goats) densities. According to these criteria, 2000 was an atypical year. These conclusions suggest that it is important to consider social variables in addition to environmental ones when assessing the risk of RVF emergence.

  7. Collie Eye Anomaly in Switzerland.

    Science.gov (United States)

    Walser-Reinhardt, L; Hässig, M; Spiess, B

    2009-12-01

    In this retrospective study, the results of 3'527 eye examinations in 6 different breeds affected with Collie Eye Anomaly (CEA) over a period of 8 years (1999 - 2007) are described. CEA was divided into three main ophthalmoscopic features, a) choroidal hypoplasia (CRH), b) CRH and coloboma and c) coloboma alone. Of the 101 Smooth Collies 8.9 % showed signs of CRH, whereas 36.9 % of Rough Collies were affected with CRH, 2.8 % with CRH and coloboma and 0.38 % with coloboma alone. Choroidal hypoplasia was present in 13.1 %, CRH and coloboma in 1.8 % and coloboma alone in 0.2 % of the Shetland Sheepdogs. Only one Australian Shepherd dog had CRH, while 0.7 % of the Border Collies were affected with CRH. None of the Nova Scotia Duck Tolling Retrievers were affected with CEA. There were no statistically significant differences in the occurrence of CEA between males and females, nor was there any relation between coat colors. Significant differences could be shown between dogs younger or older than 8 weeks at first examination. CEA was more often diagnosed in dogs younger than 8 weeks within the Rough Collie and Shetland Sheepdog.

  8. ANALISIS KUALITAS AUDIT TERHADAP MANAJEMEN LABA AKUNTANSI: STUDI PENDEKATAN COMPOSITE MEASURE VERSUS CONVENTIONAL MEASURE

    Directory of Open Access Journals (Sweden)

    Antonius Herusetya

    2012-12-01

    Full Text Available This study investigates the effect of audit quality on earnings management behavior using a variety of audit quality proxies, either using a single proxy or a joint test of some proxies of audit quality. The study proposed a new composite measure of audit quality called the Audit Quality Metric Score (AQMS, which represents the dimension of competence and independence of audit quality. The study compared the validity of the conventional and the multidimensional measurement of audit quality. With a sample of 1,152 firm-years panel data of non-financial companies listed in the Indonesia Stock Exchange (IDX for the year 1999-2007, the study found a negative effect of audit quality over the accrual earnings management, whether using conventional or multidimensional measures of audit quality. These findings are consistent with the previous findings. The study did not find evidence that composite measure of audit quality has higher validity than conventional measures. Rather, we found evidence that Big 4 as a single proxy of audit quality has higher validity compared to the other proxies or using AQMS. The findings of this study are robust due to sensitivity test that support the main findings.

  9. Cryotherapy

    International Nuclear Information System (INIS)

    Shinohara, Katsuko

    2007-01-01

    Cryotherapy is a method to ablate tissues by the local induction of extremely low temperatures, and has recently attracted considerable attention as an alternative, promising treatment of localized prostate (P) cancer. This paper describes fundamentals, clinical applications and future aspects of the method in the P cancer treatment in the following order: History of the therapy; Cryobiology; Cryotherapy equipment; Patient selection; Preoperative considerations; Procedure and follow-up; Complications; Outcome and prognosis; and Future development and controversies. The current, 3rd generation cryogenic machine like SeedNet (Galil Oncura) uses liquid argon as a cryogen and has needle-shaped cryo-probes to be placed in P to make conformal freezing. The salvage treatment is an alternative therapy in patient selection for those previously undergone with other treatment like radiation. In the cryotherapy procedure, the transrectal US probe is firstly inserted for guidance of the cryo-probes and other sensors. Most frequent complication involves impotence and incontinence. In reports in 1999-2007 of the primary cryotherapy, biochemical (i.e., the prostate-specific antigen (PSA) level) disease-free survivals (bDFS, in %) are 69-84, 71-89, and 45-89 in low, intermediate and high risk groups, respectively, and local recurrence (%), 10-38. For the salvage therapy in 1997-2004, bDFS are 34-72% and the recurrence, 0-23%. It seems likely that cryosurgery will play a more important role in prostate cancer management in future. (R.T.)

  10. Tv-serien som vor tids roman?

    DEFF Research Database (Denmark)

    Nielsen, Jakob Isak

    2012-01-01

    Artiklen gør rede for de forbindelseslinjer, der er mellem den nyere amerikanske tv-serie og en række andre udtryksformer (fx radiospillet og spillefilmen) for dernæst at fokusere på tv-seriens slægtskab med romanen. Alene i Danmark har såvel kulturjournalister som forskere påpeget ligheder de...... to udtryksformer imellem, og artiklen vil forsøge at skabe et overblik over berøringsfladerne og parallellerne. Artiklens tese er, at sammenligningen er gangbar i forhold til en række parametre – særligt hvis man indsnævrer de i udgangspunktet temmelig heterogene og vidtfavnende udtryksformer ”romanen” og ”tv......-serien” og fokuserer på bestemte eksempler og strømninger samt på bestemte distributions-, brugs- og oplevelsesformer (særligt DVD-udgivelsen ifm. tv-serier fx). Eksemplerne er primært fra en række nyere amerikanske tv-serier fra The Sopranos (HBO, 1999-2007) og frem, og artiklen vil afslutningsvist påpege...

  11. Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort.

    Science.gov (United States)

    Olofsson, Tor; Petersson, Ingemar F; Eriksson, Jonas K; Englund, Martin; Simard, Julia F; Nilsson, Jan-Åke; Geborek, Pierre; Jacobsson, Lennart T H; Askling, Johan; Neovius, Martin

    2014-05-01

    To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). Individuals aged 19-59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999-2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and baseline predictors of total work days lost during 3 years after RA diagnosis were investigated using linear regression. Due to effect modification by baseline work ability (defined as work days lost the month before diagnosis), analyses were stratified into three categories: full=0 work days lost the month before diagnosis; partial=1-29 work days lost; and none=30 work days lost. 71% of patients with full baseline work ability still had full work ability after 3 years compared with 36% (ppension. Taking this into account, HAQ, DAS28, age and education level were also significant predictors, whereas ESR and CRP were not.

  12. Trend in the use of intra-uterine contraceptive device (IUCD ,TCU 380A), in Enugu, Nigeria.

    Science.gov (United States)

    Ezegwui, H U; Nwogu-Ikojo, E E; Ikeako, L C; Nweze, S

    2013-01-01

    To estimate the acceptance rate and trend of Intrauterine Contraceptive Device (IUCD) use in Enugu, Nigeria A review of all new acceptors of intrauterine contraceptive device (IUCD) over a nine year period (1999-2007). A total of 133,375 clients were seen at the UNTH family planning clinic between 1999 and 2007. Out of 6,947 users of IUCD, during the period, 1,659 were new acceptors. The IUCD acceptance rate was 5.21%. Majority of the clients (29.7%) were aged 40 years and above. Eight hundred and forty seven (51.4%) had attained post secondary education. Majority of the clients (99.4%) were married . Twenty-six percent (26.0%) had completed their desired family size. Majority 1,359 (82.4%) did not use any method contraception prior to IUCD insertion. The commonest complication was menorrhagia (5.8%) and this was responsible for removal in 3.0% of cases. Eight (0.5%) and nine (0.6%) requested for removal for fear of causing cancer and migration to the brain or heart respectively. Two (0.1%) became pregnant while having the IUCD in-situ. Majority of the clients (50.5%) had the knowledge of lUCD through friends. This study has shown that IUCD (TCU 380A) is both safe and effective in Enugu, Nigeria. Its use is for both child spacing and limiting family size.

  13. Malnutrition related deaths.

    Science.gov (United States)

    Sparre-Sørensen, Maja; Kristensen, Gustav N

    2016-10-01

    Studies have shown that malnutrition increases the risk of morbidity, mortality, the length of hospital stay, and costs in the elderly population. Approximately one third of all patients admitted to geriatric wards in Denmark are malnourished according to the Danish Geriatric database. The aim of this study is to describe and examine the sudden increase in deaths due to malnutrition in the elderly population in Denmark from 1999 and, similarly, the sudden decline in malnutrition related deaths in 2007. A descriptive epidemiologic study was performed. All Danes listed in the national death registry who died from malnutrition in the period from 1994 to 2012 are included. The number of deaths from malnutrition increased significantly during the period from 1999 to 2007, especially in the age group 70 years and over. Additionally, we document a surprising similarity between the development in excess mortality from malnutrition in the five Danish regions during the same period. During the period 1999-2007 malnutrition was the direct cause of 340 extra deaths, and probably ten times more registered under other diseases. This development in excess mortality runs parallel in all five Danish regions over time. Copyright © 2016 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.

  14. Measuring Spatiotemporal Features of Land Subsidence, Groundwater Drawdown, and Compressible Layer Thickness in Beijing Plain, China

    Directory of Open Access Journals (Sweden)

    Yongyong Li

    2017-01-01

    Full Text Available Beijing is located on multiple alluvial-pluvial fans with thick Quaternary unconsolidated sediments. It has suffered serious groundwater drawdown and land subsidence due to groundwater exploitation. This study aimed to introduce geographical distribution measure methods into land subsidence research characterizing, geographically, land subsidence, groundwater drawdown, and compressible layer thickness. Therefore, we used gravity center analysis and standard deviational ellipse (SDE methods in GIS to statistically analyze their concentration tendency, principle orientation, dispersion trend, and distribution differences in 1995 (1999, 2007, 2009, 2011, and 2013. Results show that they were all concentrated in Chaoyang District of Urban Beijing. The concentration trend of land subsidence was consistent with that of groundwater drawdown. The principle orientation of land subsidence was SW–NE, which was more similar with that of the static spatial distribution of the compressible layer. The dispersion tendency of land subsidence got closer to that of the compressible layer with its increasing intensity. The spatial distribution difference between land subsidence and groundwater drawdown was about 0.2, and that between land subsidence and compressible layer thickness it decreased from 0.22 to 0.07, reflecting that the spatial distribution pattern of land subsidence was increasingly close to that of the compressible layer. Results of this study are useful for assessing the distribution of land subsidence development and managing groundwater resources.

  15. Rate of Clinical Complete Response for 1 Year or More in Bone-Metastatic Breast Cancer after Comprehensive Treatments including Autologous Formalin-Fixed Tumor Vaccine.

    Science.gov (United States)

    Kuranishi, Fumito; Imaoka, Yuki; Sumi, Yuusuke; Uemae, Yoji; Yasuda-Kurihara, Hiroko; Ishihara, Takeshi; Miyazaki, Tsubasa; Ohno, Tadao

    2018-01-01

    No effective treatment has been developed for bone-metastatic breast cancer. We found 3 cases with clinical complete response (cCR) of the bone metastasis and longer overall survival of the retrospectively examined cohort treated comprehensively including autologous formalin-fixed tumor vaccine (AFTV). AFTV was prepared individually for each patient from their own formalin-fixed and paraffin-embedded breast cancer tissues. Three patients maintained cCR status of the bone metastasis for 17 months or more. Rate of cCR for 1 year or more appeared to be 15% (3/20) after comprehensive treatments including AFTV. The median overall survival time (60.0 months) and the 3- to 8-year survival rates after diagnosis of bone metastasis were greater than those of historical control cohorts in Japan (1988-2002) and in the nationwide population-based cohort study of Denmark (1999-2007). Bone-metastatic breast cancer may be curable after comprehensive treatments including AFTV, although larger scale clinical trial is required.

  16. A infuência de O Poderoso Chefão na narrativa de Família Soprano = The infuence of The Godfather in the Sopranos storytelling

    Directory of Open Access Journals (Sweden)

    Pires, Cristine de Andrade

    2015-01-01

    Full Text Available O Poderoso Chefão (The Godfather, Francis Ford Coppola, 1972 é considerado paradigma entre os filmes de máfia. Entre os seriados de tevê, Família Soprano (The Sopranos, David Chase, 1999-2007 surge como principal representante do gênero. De acordo com autores como Messenger (2002, Santopietro (2012 e Martin (2014, a presença da família Corleone, que protagonizou a trilogia mafiosa de Coppola, é marca constante durante as oito temporadas de Família Soprano. Essa presença, no entanto, não se dá apenas de forma explícita. Há muitas mensagens subliminares. O objetivo deste estudo é analisar essas duas grandes produções, que entraram para a história em mídias e momentos históricos diferentes, e verifcar de que forma o comportamento da família Corleone entra no lar e na rotina da gangue de Tony Soprano

  17. The MarineGrid project in Ireland with Webcom

    Science.gov (United States)

    Kenirons, Martin; Curran, Oisín; Cunniffe, John; Ryan, Jenny; Ryan, Paul; Shearer, Andrew

    2009-02-01

    The 1999-2007 Irish National Seabed Survey is one of the largest ocean floor mapping projects ever attempted. Its aim is to map the ocean floor of the Irish territorial waters (approximately 525000km2). To date, the Geological Survey of Ireland has gathered in excess of 4 TB of multibeam sonar data from the Irish National Seabed, and this data set is expected to exceed 10 TB upon completion. The main challenge that arises from having so much data is how to extract accurate information given the size of the data set. Geological interpretation is carried out by visual inspection of bathymetric patterns. The size of this, and similar, data sets renders the extraction of knowledge by human observers infeasible. Consequently, the focus has turned to using artificial intelligence and computational methods for assistance. The commercial and environmental sensitivity of the data means that secure data processing and transmission are of paramount importance. This has lead to the creation of the MarineGrid project within the Grid-Ireland organisation. New methods have been developed for statistical analysis of bathymetric information specifically for automated geological interpretation of rock types on the sea floor and feature extraction from the sea floor. We present a discussion on how to provide Marine and Geological researchers convenient yet secure access to resources that make use of grid technologies including pre-written algorithms in order to exploit the Irish National Seabed Survey data archive.

  18. Suicide, unemployment, and economic recession in Spain.

    Science.gov (United States)

    Iglesias-García, Celso; Sáiz, Pilar A; Burón, Patricia; Sánchez-Lasheras, Fernando; Jiménez-Treviño, Luis; Fernández-Artamendi, Sergio; Al-Halabí, Susana; Corcoran, Paul; García-Portilla, M Paz; Bobes, Julio

    The aim of the present work is to determine the association between unemployment and suicide, and to investigate whether this association is affected by changes in the economic cycle or other variables such as age and sex. A time-trend analysis was conducted to study changes in the number of suicides between 1999 and 2013 in Spain. Pearson's correlation coefficients and regression models were used to find the association between unemployment and suicide. A significant positive association was found between unemployment and suicide in the pre-crisis period in men. In that period (1999-2007), each 1% annual increase in unemployment was associated with a 6.90% increase in the annual variation of suicide in the total population, and with a 9.04% increase in the annual variation of suicide in working age men. The correlation between unemployment and suicide is significant in periods of economic stability, but has weakened during the recent financial crisis. Unemployment and suicide have a complex relationship modulated by age, sex and economic cycle. Copyright © 2017 SEP y SEPB. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. El papel de la memoria operativa en las diferencias y trastornos del aprendizaje escolar

    Directory of Open Access Journals (Sweden)

    Óscar Sierra Fitzgerald

    2013-01-01

    Full Text Available Los mecanismos neurocognitivos que permiten la construcción de los conceptos académicos durante la escolaridad formal son complejos. Recientemente la comunidad científica ha comenzado a reconocer el lugar transversal de la memoria operativa, como una función cognitiva compleja, en la conceptualización de las diferencias individuales en el aprendizaje escolar, permitiéndose así explicar los trastornos en el aprendizaje en las diversas áreas del conocimiento. Tomando distancia de la definición clásica de los trastornos del aprendizaje y de la concomitante manera de evaluarlos; durante la última década muchos investigadores han enfatizado la relación entre la memoria operativa, desde el modelo de multicomponentes de Baddeley y Hitch (1974, y el aprendizaje escolar. Contextualizada en la teoría evolutiva de Geary (1999-2007 y la perspectiva histórico-cultural de Vygotski (1934, esta nueva perspectiva se explora a profundidad en el presente trabajo. De esta forma, el artículo presenta la revisión de una serie de estudios de investigación que se pueden clasificar en cuatro grupos que han mostrado la compleja relación entre la memoria operativa y el aprendizaje escolar, tanto en el aprendizaje de las matemáticas como en el de la lectura.

  20. Markov chains-cellular automata modeling and multicriteria analysis of land cover change in the Lower Nhecolândia subregion of the Brazilian Pantanal wetland

    Science.gov (United States)

    Bacani, Vitor Matheus; Sakamoto, Arnaldo Yoso; Quénol, Hervé; Vannier, Clémence; Corgne, Samuel

    2016-01-01

    The dynamics of land use/land cover change in the Lower Nhecolândia wetland are marked by deforestation for pasture expansion, resulting in a real threat to the ecological stability. The aim of our work was to analyze the spatial distribution of land cover changes in the Lower Nhecolândia from 1985 to 2013 and to predict changes in trends for 2040. The mapping of land cover changes was developed using Landsat satellite images of 1985, 1999, 2007, and 2013, based on geographic object-based image analysis approach. This study uses integrated Markov chains and cellular automata modeling and multicriteria evaluation techniques to produce transition probability maps and describe the trajectory analysis methodology to construct a continuity of spatial and temporal changes for the wetland. The results of the multitemporal change detection classification show that, from 1985 to 2013, the forest woodland decreased by 6.89% and the grassland class increased by 18.29%. On the other hand, all water bodies showed a reducing trend, while the bare soil class increased compared to 1985, but did not present a regular trend of increase or decrease. From the present day, the trend for the future is a reduction of almost 6.4% by 2040. We found that deforestation actions will be concentrated in the areas with the highest concentration of saline lakes, constituting a serious threat to the natural functioning of this environmental system.

  1. Identification of genetic loci shared between schizophrenia and the Big Five personality traits.

    Science.gov (United States)

    Smeland, Olav B; Wang, Yunpeng; Lo, Min-Tzu; Li, Wen; Frei, Oleksandr; Witoelar, Aree; Tesli, Martin; Hinds, David A; Tung, Joyce Y; Djurovic, Srdjan; Chen, Chi-Hua; Dale, Anders M; Andreassen, Ole A

    2017-05-22

    Schizophrenia is associated with differences in personality traits, and recent studies suggest that personality traits and schizophrenia share a genetic basis. Here we aimed to identify specific genetic loci shared between schizophrenia and the Big Five personality traits using a Bayesian statistical framework. Using summary statistics from genome-wide association studies (GWAS) on personality traits in the 23andMe cohort (n = 59,225) and schizophrenia in the Psychiatric Genomics Consortium cohort (n = 82,315), we evaluated overlap in common genetic variants. The Big Five personality traits neuroticism, extraversion, openness, agreeableness and conscientiousness were measured using a web implementation of the Big Five Inventory. Applying the conditional false discovery rate approach, we increased discovery of genetic loci and identified two loci shared between neuroticism and schizophrenia and six loci shared between openness and schizophrenia. The study provides new insights into the relationship between personality traits and schizophrenia by highlighting genetic loci involved in their common genetic etiology.

  2. The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States

    Science.gov (United States)

    Bryc, Katarzyna; Durand, Eric Y.; Macpherson, J. Michael; Reich, David; Mountain, Joanna L.

    2015-01-01

    Over the past 500 years, North America has been the site of ongoing mixing of Native Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave trade), shaping the early history of what became the United States. We studied the genetic ancestry of 5,269 self-described African Americans, 8,663 Latinos, and 148,789 European Americans who are 23andMe customers and show that the legacy of these historical interactions is visible in the genetic ancestry of present-day Americans. We document pervasive mixed ancestry and asymmetrical male and female ancestry contributions in all groups studied. We show that regional ancestry differences reflect historical events, such as early Spanish colonization, waves of immigration from many regions of Europe, and forced relocation of Native Americans within the US. This study sheds light on the fine-scale differences in ancestry within and across the United States and informs our understanding of the relationship between racial and ethnic identities and genetic ancestry. PMID:25529636

  3. [Estimates of effective population size inPinus silvestris].

    Science.gov (United States)

    Stern, K; Gregorius, H R

    1972-01-01

    The effective population size for inbreeding has been estimated in a 70 years old population of Scotch Pine in three consecutive years to be 0.46, 0.55 and 0.61 respectively of the actual total population. The following formula was developed to determine differences among trees as regards their male or female flowering and their "maleness" and "femaleness":[Formula: see text] wheren e is the total effective population size for inbreeding,n e ' the male effective part,n e ″ the female effective part, andM a measure for monoecy ranging in values between zero (dioecy) and unity (ideal monoecy). The degree of monoecy was 70, 82 and 78 percent respectively in the three years.Correlation between male flowering over the three years was fairly strong; the same was found for female flowering. But correlation between male and female flowering was weak, both within the same year and over the three year period. Correlation of numbers of female strobili and numbers of ripe cones was weak also.The population model on which the above formulae is based is that of a clonal 'Seed Orchard' where seedlings of several clones are randomly distributed on evenly spaced plots.

  4. Research 2.0: social networking and direct-to-consumer (DTC) genomics.

    Science.gov (United States)

    Lee, Sandra Soo-Jin; Crawley, LaVera

    2009-01-01

    The convergence of increasingly efficient high throughput sequencing technology and ubiquitous Internet use by the public has fueled the proliferation of companies that provide personal genetic information (PGI) direct-to-consumers. Companies such as 23andme (Mountain View, CA) and Navigenics (Foster City, CA) are emblematic of a growing market for PGI that some argue represents a paradigm shift in how the public values this information and incorporates it into how they behave and plan for their futures. This new class of social networking business ventures that market the science of the personal genome illustrates the new trend in collaborative science. In addition to fostering a consumer empowerment movement, it promotes the trend of democratizing information--openly sharing of data with all interested parties, not just the biomedical researcher--for the purposes of pooling data (increasing statistical power) and escalating the innovation process. This target article discusses the need for new approaches to studying DTC genomics using social network analysis to identify the impact of obtaining, sharing, and using PGI. As a locus of biosociality, DTC personal genomics forges social relationships based on beliefs of common genetic susceptibility that links risk, disease, and group identity. Ethical issues related to the reframing of DTC personal genomic consumers as advocates and research subjects and the creation of new social formations around health research may be identified through social network analysis.

  5. When Markers Meet Marketing: Ethnicity, Race, Hybridity, and Kinship in Genetic Genealogy Television Advertising

    Directory of Open Access Journals (Sweden)

    Christine Scodari

    2017-12-01

    Full Text Available The essay explores issues pertaining to genetics vs. culture in understandings of kinship, hybridity as a disruptor of essentialist conceptions of race, the fetishization of ethnicity and culture, racist misuses of genetic science, processes of racialization, and counter-hegemonic resistance. Thirty- and sixty-second television advertisements airing in the U.S. from the 23andMe and AncestryDNA genetic genealogy testing services are analyzed in this context. The investigation demonstrates that genetic ancestry testing providers are well aware that their enterprise is premised on belief in the superiority of biological kinship and that hybridity is mobilized primarily as a marketing opportunity with ethnic components signified in shorthand by fetishized objects. Moreover, the categories of race and ethnicity presented in the ads give cover to racist abusers of genetic science, as the ads are consistent with socially constructed racial classifications. While maintaining this consistency, the categories are subject to adjustment based on the expectations of consumers. Resistance is possible in the use of genetic ancestry by descendants of African slaves to make localized connections to Africa, something that conventional genealogy seldom provides.

  6. Geodesic acoustic mode (GAM) like oscillations and RMP effect in the STOR-M tokamak

    Science.gov (United States)

    Basu, Debjyoti; Nakajima, Masaru; Melnikov, A. V.; McColl, David; Rohollahi, Akbar; Elgriw, Sayf; Xiao, Chijin; Hirose, Akira

    2018-02-01

    A new kind of quasi-coherent mode was observed in ohmic plasma in the STOR-M tokamak. It is featured with a clear solitary peak around 30–35 kHz in the power spectra of the ion saturation current (I_sat) of Langmuir probe as well as poloidal and toroidal mode numbers (m  =  1,n  =  0) as per the prediction of conventional geodesic acoustic mode (GAM) theory. The dispersion relation of the mode is also similar to GAM and it also shows collisional damping. In contrast to conventional GAM, the floating potential ϕ of the observed GAM-like mode does not show similar symmetric poloidal and toroidal mode numbers (m  =  0,n  =  0), but has (m  =  1,n  =  1). The GAM-like mode has also a pronounced magnetic component with mixed poloidal modes (m=3~and~m=5; n=1 ), as observed by Mirnov coils. This mode is suppressed by the application of resonance magnetic perturbations.

  7. President Ilves andis teenetemärgi 268 inimesele

    Index Scriptorium Estoniae

    2008-01-01

    Eesti Vabariigi 90. aastapäeva puhul riiklike autasudega tunnustatud isikute nimekiri. Vt. samas: Allar Viivik. Ärimees ja kirjanik on saanud kolm autasu. Kolm teenetemärki on saanud kirjanik ja riigitegelane Lehte Sööt (Hainsalu) ning ärimees Toomas Luman; Kadri Paas. Valgetähe orden purjutajast naaklejale. President Toomas Hendrik Ilves annab Valgetähe III klassi ordeni Indrek Tarandile kaasa aitamise eest Eesti liitumisele Euroopa Liidu ja NATOga; Teenetemärke on antud välja 5544. Eesti riiklikke teenetemärke jagab Vabariigi President 1995. aastast. Statistilised andmed eri aastatel antud teenetemärkide kohta. Vt. ka lk. 10 juhtkiri: Ärma ordenipuu. Autasustatute nimekiri ilmunud ka: Eesti Päevaleht 7. veebr. 2008, lk. 8-9, pealk.: Vabariigi president Toomas Hendrik Ilves jagab teenetemärke; Postimees 7. veebr. 2008, lk. 12-15, pealk.: Riiklike teenetemärkide saajad; Postimees : na russkom jazõke 7. veebr. 2008, lk. 2, 4-5 ; Maaleht 7. veebr. 2008, lk. 12-13, pealk.: Eesti tänab 2008; Linnaleht : Tallinn 7. veebr. 2008, lk. 4, pealk.: Eesti tänab; Eesti Päevaleht (Stockholm) 21. veebr. 2008, lk. 3, 11, pealk.: Selgusid 2008. aasta Eesti riiklikud autasud; Eesti Elu 22. veebr. 2008, lk. 12-13, pealk.: Riiklike autasude andmine

  8. Simultaneous determination of some artificial sweeteners in ternary formulations by FT-IR and EI-MS

    Science.gov (United States)

    Tosa, Nicoleta; Moldovan, Zaharie; Bratu, Ioan

    2012-02-01

    Artificial sweeteners are widely used in food, beverage and pharmaceutical industries all over the world. In this study some non-nutritive sweeteners such as aspartame, acesulfame-K, sodium cyclamate and sodium saccharin were simultaneously determined in ternary mixtures using FT-IR and EI-MS measurements. FT-IR method is based on direct measurements of the peak height values and area centered on 1736 cm-1, 836 cm-1, 2854 cm-1 and 1050 cm-1 for aspartame, acesulfame-K, sodium cyclamate and sodium saccharin, respectively. Mass spectrometry determinations show the characteristic peaks at m/z 91 and 262 for aspartame,m/z 43 and 163 acesulfame-K,m/z 83 and 97 for sodium cyclamate andm/z 104 and 183 for sodium saccharin. The results obtained by EI-MS in different formulations are in agreement with the FT-IR ones and provide also essential data concerning the purity grade of the components. It is concluded that FT-IR and EI-MS procedures developed in this work represent a fast, sensitive and low cost alternative in the quality control of such sweeteners in different ternary formulations.

  9. Replication and characterization ofCADM2andMSRAgenes on human behavior.

    Science.gov (United States)

    Boutwell, Brian; Hinds, David; Tielbeek, Jorim; Ong, Ken K; Day, Felix R; Perry, John R B

    2017-07-01

    Progress identifying the genetic determinants of personality has historically been slow, with candidate gene studies and small-scale genome-wide association studies yielding few reproducible results. In the UK Biobank study, genetic variants in CADM2 and MSRA were recently shown to influence risk taking behavior and irritability respectively, representing some of the first genomic loci to be associated with aspects of personality. We extend this observation by performing a personality "phenome-scan" across 16 traits in up to 140,487 participants from 23andMe for these two genes. Genome-wide heritability estimates for these traits ranged from 5-19%, with both CADM2 and MSRA demonstrating significant effects on multiple personality types. These associations covered all aspects of the big five personality domains, including specific facet traits such as compliance, altruism, anxiety and activity/energy. This study both confirms and extends the original observations, highlighting the role of genetics in aspects of mental health and behavior.

  10. Replication and characterization of CADM2 and MSRA genes on human behavior

    Directory of Open Access Journals (Sweden)

    Brian Boutwell

    2017-07-01

    Full Text Available Progress identifying the genetic determinants of personality has historically been slow, with candidate gene studies and small-scale genome-wide association studies yielding few reproducible results. In the UK Biobank study, genetic variants in CADM2 and MSRA were recently shown to influence risk taking behavior and irritability respectively, representing some of the first genomic loci to be associated with aspects of personality. We extend this observation by performing a personality “phenome-scan” across 16 traits in up to 140,487 participants from 23andMe for these two genes. Genome-wide heritability estimates for these traits ranged from 5–19%, with both CADM2 and MSRA demonstrating significant effects on multiple personality types. These associations covered all aspects of the big five personality domains, including specific facet traits such as compliance, altruism, anxiety and activity/energy. This study both confirms and extends the original observations, highlighting the role of genetics in aspects of mental health and behavior.

  11. THE BENEFITS OF CUSTOMIZED DNA DIRECTED NUTRITION TO BALANCE THE BRAIN REWARD CIRCUITRY AND REDUCE ADDICTIVE BEHAVIORS

    Science.gov (United States)

    Blum, Kenneth; Downs, B.W.; Dushaj, Kristina; Li, Mona; Braverman, Eric R.; Fried, Lyle; Waite, Roger; Demotrovics, Zsolt; Badgaiyan, Rajendra D.

    2016-01-01

    DNA Customization of nutraceutical products is here. In the truest sense, “Gene Guided Precision Nutrition™” and KB220 variants (a complex mixture of amino–acids, trace metals, and herbals) are the pioneers and standard-bearers for a state of the art DNA customization. Findings by both, Kenneth Blum, Ph.D. and Ernest Noble, Ph.D. concerning the role of genes in shaping cravings and pleasure- seeking, opened the doors to comprehension of how genetics control our actions and effect our mental and physical health. Moreover, technology that is related to KB220 variants in order to reduce or eradicate excessive cravings by influencing gene expression is a cornerstone in the pioneering of the practical applications of nutrigenomics. Continuing discoveries have been an important catalyst for the evolution, expansion, and scientific recognition of the significance of nutrigenomics and its remarkable contributions to human health. Neuro-Nutrigenomics is now a very important field of scientific investigation that offers great promise to improving the human condition. In the forefront is the development of the Genetic Addiction Risk Score (GARS™), which unlike 23andMe, has predictive value for the severity of drug and alcohol abuse as well as other non-substance related addictive behaviors. While customization of neuronutrients has not yet been commercialized, there is emerging evidence that in the future, the concept will be developed and could have a significant impact in addiction medicine. PMID:28066828

  12. Consumers report lower confidence in their genetics knowledge following direct-to-consumer personal genomic testing.

    Science.gov (United States)

    Carere, Deanna Alexis; Kraft, Peter; Kaphingst, Kimberly A; Roberts, J Scott; Green, Robert C

    2016-01-01

    The aim of this study was to measure changes to genetics knowledge and self-efficacy following personal genomic testing (PGT). New customers of 23andMe and Pathway Genomics completed a series of online surveys. We measured genetics knowledge (nine true/false items) and genetics self-efficacy (five Likert-scale items) before receipt of results and 6 months after results and used paired methods to evaluate change over time. Correlates of change (e.g., decision regret) were identified using linear regression. 998 PGT customers (59.9% female; 85.8% White; mean age 46.9 ± 15.5 years) were included in our analyses. Mean genetics knowledge score was 8.15 ± 0.95 (out of 9) at baseline and 8.25 ± 0.92 at 6 months (P = 0.0024). Mean self-efficacy score was 29.06 ± 5.59 (out of 35) at baseline and 27.7 ± 5.46 at 6 months (P perceived control over one's health (P perceived value of PGT (P consumers in response to receiving complex genetic information.Genet Med 18 1, 65-72.

  13. A Review on Genomics APIs

    Directory of Open Access Journals (Sweden)

    Rajeswari Swaminathan

    2016-01-01

    Full Text Available The constant improvement and falling prices of whole human genome Next Generation Sequencing (NGS has resulted in rapid adoption of genomic information at both clinics and research institutions. Considered together, the complexity of genomics data, due to its large volume and diversity along with the need for genomic data sharing, has resulted in the creation of Application Programming Interface (API for secure, modular, interoperable access to genomic data from different applications, platforms, and even organizations. The Genomics APIs are a set of special protocols that assist software developers in dealing with multiple genomic data sources for building seamless, interoperable applications leading to the advancement of both genomic and clinical research. These APIs help define a standard for retrieval of genomic data from multiple sources as well as to better package genomic information for integration with Electronic Health Records. This review covers three currently available Genomics APIs: a Google Genomics, b SMART Genomics, and c 23andMe. The functionalities, reference implementations (if available and authentication protocols of each API are reviewed. A comparative analysis of the different features across the three APIs is provided in the Discussion section. Though Genomics APIs are still under active development and have yet to reach widespread adoption, they hold the promise to make building of complicated genomics applications easier with downstream constructive effects on healthcare.

  14. Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment.

    Science.gov (United States)

    Shaffer, John R; Li, Jinxi; Lee, Myoung Keun; Roosenboom, Jasmien; Orlova, Ekaterina; Adhikari, Kaustabh; Gallo, Carla; Poletti, Giovanni; Schuler-Faccini, Lavinia; Bortolini, Maria-Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; González-José, Rolando; Pfeffer, Paige E; Wollenschlaeger, Christopher A; Hecht, Jacqueline T; Wehby, George L; Moreno, Lina M; Ding, Anan; Jin, Li; Yang, Yajun; Carlson, Jenna C; Leslie, Elizabeth J; Feingold, Eleanor; Marazita, Mary L; Hinds, David A; Cox, Timothy C; Wang, Sijia; Ruiz-Linares, Andrés; Weinberg, Seth M

    2017-12-07

    The genetic basis of earlobe attachment has been a matter of debate since the early 20 th century, such that geneticists argue both for and against polygenic inheritance. Recent genetic studies have identified a few loci associated with the trait, but large-scale analyses are still lacking. Here, we performed a genome-wide association study of lobe attachment in a multiethnic sample of 74,660 individuals from four cohorts (three with the trait scored by an expert rater and one with the trait self-reported). Meta-analysis of the three expert-rater-scored cohorts revealed six associated loci harboring numerous candidate genes, including EDAR, SP5, MRPS22, ADGRG6 (GPR126), KIAA1217, and PAX9. The large self-reported 23andMe cohort recapitulated each of these six loci. Moreover, meta-analysis across all four cohorts revealed a total of 49 significant (p < 5 × 10 -8 ) loci. Annotation and enrichment analyses of these 49 loci showed strong evidence of genes involved in ear development and syndromes with auricular phenotypes. RNA sequencing data from both human fetal ear and mouse second branchial arch tissue confirmed that genes located among associated loci showed evidence of expression. These results provide strong evidence for the polygenic nature of earlobe attachment and offer insights into the biological basis of normal and abnormal ear development. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  15. The X-Ray Diffraction Analysis and Spectral Studies of Mixed Anionic (1:1) Cd II3[(Fe III/Co III)(CN) 6] 2·14H 2O

    Science.gov (United States)

    Mullica, D. F.; Colot, P. A. B.; Kautz, J. A.; Smith, R. J.; Sappenfield, E. L.

    1997-02-01

    Refinement of the crystallographic structure of (1:1) CdII3[(FeIII/CoIII)(CN)6]2·14H2O (I) has been carried out by means of three-dimensional single-crystal X-ray diffractometry. This novel disordered mixed anionic complex crystallizes in the cubic space groupFmoverline3m(Z=11/3) witha0=10.638(1) Å. Based on 166 unique reflections, the employed full-matrix least-squares method yielded a final reliability factor ofR=0.041 (Rw=0.047) and a goodness-of-fit value (Σ2) of 1.79. Indexed power diffraction data are reported and evaluated according to the quantitative figures-of-meritF21=114 (0.007, 25) andM20=154.9. A thermal gravimetric analysis revealed 14 water molecules per formula unit and the experimental density is 1.93(5) Mg m-3[calc., 1.87(1) Mg m-3]. The divalent Cd atoms are linked to the (1:1) mixed metal atoms by linear cyanide bridging. The disordered structure I is isomorphous with the hydrated cobalticyanides of Mn and Cd. A hydrogen-bonding network is set up within cavities of the crystal lattice created by the molecular disorder. Selective geometric parameters as well as conoscopic and IR spectral results are presented.

  16. Computation of fractal features based on the fractal analysis of surface electromyogram to estimate force of contraction of different muscles.

    Science.gov (United States)

    Poosapadi Arjunan, Sridhar; Kumar, Dinesh Kant

    2014-01-01

    This research study investigates the fractal properties of surface Electromyogram (sEMG) to estimate the force levels of contraction of three muscles with different cross-sectional areas (CSA): m. quadriceps--vastus lateralis, m. biceps brachii, andm. flexor digitorum superficialis. The fractal features were computed based on the fractal analysis of sEMG, signal recorded while performing sustained muscle contraction at different force levels. A comparison was performed between the fractal features and five other features reported in the literature. Linear regression analysis was carried out to determine the relationship between the force of contraction (20-100%) and features of sEMG. The results from the coefficients of regression r² show that the new fractal feature, maximum fractal length of the signal has highest correlation (range 0.88-0.90) when compared with other features which ranges from 0.34 to 0.74 for the three different muscles. This study suggests that the estimation of various levels of sustained contraction of muscles with varied CSA will provide a better insight into the biomechanics model that involves muscle properties and muscle activation.

  17. Symmetries of Quadrupole-Collective Vibrational Motion in Transitional Even-Even 124−134Xenon Nuclei

    CERN Document Server

    Pietralla, N; Rainovski, G; Ahn, T; Bauer, C; Leske, J; Möller, O; Möller, T

    2010-01-01

    Projectile-Coulomb excitation of Xe isotopes has been performed at ANL using the Gammasphere array for the detection of γ-rays. The one-quadrupole phonon 2+ 1,ms mixed-symmetry state (MSS) has been traced in the stable N=80 isotones down to 134Xe. First, the data on absolute E2 andM1 transition rates quantify the amount of F-spin symmetry in these nuclei and provide a new local measure for the pn-QQ interaction. Second, the evolution of the 2+ 1,ms state has been studied along the sequence of stable even-even 124−134Xe isotopes that are considered to form a shape transition path from vibrational nuclei with vibrational U(5) symmetry near N=82 to γ-softly deformed shapes with almost O(6) symmetry. Third, our data on more than 50 absolute E2 transition rates between off-yrast low-spin states of 124,126Xe enable us to quantitatively test O(6) symmetry in these nuclei. As a result we find that O(6) symmetry is more strongly broken in the A=130 mass region than previously thought. The data will be discussed.

  18. The genetic ancestry of African Americans, Latinos, and European Americans across the United States.

    Science.gov (United States)

    Bryc, Katarzyna; Durand, Eric Y; Macpherson, J Michael; Reich, David; Mountain, Joanna L

    2015-01-08

    Over the past 500 years, North America has been the site of ongoing mixing of Native Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave trade), shaping the early history of what became the United States. We studied the genetic ancestry of 5,269 self-described African Americans, 8,663 Latinos, and 148,789 European Americans who are 23andMe customers and show that the legacy of these historical interactions is visible in the genetic ancestry of present-day Americans. We document pervasive mixed ancestry and asymmetrical male and female ancestry contributions in all groups studied. We show that regional ancestry differences reflect historical events, such as early Spanish colonization, waves of immigration from many regions of Europe, and forced relocation of Native Americans within the US. This study sheds light on the fine-scale differences in ancestry within and across the United States and informs our understanding of the relationship between racial and ethnic identities and genetic ancestry. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  19. THE BENEFITS OF CUSTOMIZED DNA DIRECTED NUTRITION TO BALANCE THE BRAIN REWARD CIRCUITRY AND REDUCE ADDICTIVE BEHAVIORS.

    Science.gov (United States)

    Blum, Kenneth; Downs, B W; Dushaj, Kristina; Li, Mona; Braverman, Eric R; Fried, Lyle; Waite, Roger; Demotrovics, Zsolt; Badgaiyan, Rajendra D

    2016-01-01

    DNA Customization of nutraceutical products is here. In the truest sense, "Gene Guided Precision Nutrition ™ " and KB220 variants (a complex mixture of amino-acids, trace metals, and herbals) are the pioneers and standard-bearers for a state of the art DNA customization. Findings by both, Kenneth Blum, Ph.D. and Ernest Noble, Ph.D. concerning the role of genes in shaping cravings and pleasure- seeking, opened the doors to comprehension of how genetics control our actions and effect our mental and physical health. Moreover, technology that is related to KB220 variants in order to reduce or eradicate excessive cravings by influencing gene expression is a cornerstone in the pioneering of the practical applications of nutrigenomics. Continuing discoveries have been an important catalyst for the evolution, expansion, and scientific recognition of the significance of nutrigenomics and its remarkable contributions to human health. Neuro-Nutrigenomics is now a very important field of scientific investigation that offers great promise to improving the human condition. In the forefront is the development of the Genetic Addiction Risk Score (GARS ™ ), which unlike 23andMe, has predictive value for the severity of drug and alcohol abuse as well as other non-substance related addictive behaviors. While customization of neuronutrients has not yet been commercialized, there is emerging evidence that in the future, the concept will be developed and could have a significant impact in addiction medicine.

  20. Indicadores de actividad tecnológica por género en España a través del estudio de patentes europeas

    Directory of Open Access Journals (Sweden)

    Mauleón, Elba

    2014-06-01

    Full Text Available Obtaining indicators of technological activity by gender is needed to increase our knowledge about the contribution of women to innovation and technological development. These activities are essential for the economic success of countries but have traditionally revealed a low presence of females. This paper adopts a “macro” approach and presents technology indicators by gender based on the analysis of the patents applied for from the European Patent Office (EPO by Spanish inventors during 1999-2007. From a total of 6,860 patents, at least one female inventor was found in 20% of the patents. Inter-gender differences in patenting are observed by institutional sector, with female involvement being above average in the public research sector; and by technological field, with a higher presence of females in chemistry. The relationship among the sex of the inventor, the institutional sector of the assignee and the technological field of the patent is explored through correspondence analysis. The article points out the relevance of patent-based indicators by gender for identifying gender inequalities in technological activity and supporting policy measures oriented to promote women’s integration in the science and technology system.El interés por los indicadores de actividad tecnológica por género responde a la necesidad de conocer cuál es la contribución de las mujeres a la innovación y al desarrollo tecnológico, actividades que son esenciales para el desarrollo económico de los países y en las que las mujeres han estado tradicionalmente poco representadas. Este trabajo asume una aproximación “macro” y presenta indicadores de actividad tecnológica por género basados en el análisis de las patentes solicitadas por inventores españoles en la Oficina Europea de Patentes (EPO en el periodo 1999-2007. Se identifican un total de 6.860 solicitudes de patente con todos sus inventores españoles, el 20% de las cuales presenta participaci

  1. Pregnancy, maternal tobacco smoking and early age leukemia in Brazil

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    Sergio eKoifman

    2012-11-01

    Full Text Available Background: Cigarette smoking has been associated with acute myeloid leukemia but hypothesis on the association between maternal smoking during pregnancy and childhood leukemia is unclear. Objectives: To investigate the association between maternal exposure to tobacco smoking during pregnancy and early age (< 2 yr. leukemia (EAL. Methods: A hospital-based multicenter case-control study aiming to explore EAL risk factors was carried out in Brazil during 1999-2007. Data were collected by direct interview with the biological mothers using a standardized questionnaire. The present study included 675 children, being 193 acute lymphoblastic leukemia (ALL, 59 acute myeloid leukemia (AML, and 423 controls, being the latter age frequency matched and paired by area of residence with the cases. Unconditional logistic regression was performed, and odds ratios (OR on the association between tobacco smoking (3 months before pregnancy, during pregnancy, and 3 months after delivery and EAL were ascertained after adjustment for selected variables (maternal age at birth and education, birth weight, infant skin color, and oral contraceptives use during pregnancy.Results: Smoking was reported by 17.5% of case mothers and 20.6% of controls´. Among women who reported to have smoked 20 or more cigarettes during the index pregnancy, an adjusted OR = 5.28 (95% C.I. 1.40-19.95 for ALL was observed. Heavy smoking during breastfeeding yielded an adjusted risk estimate for ALL, OR = 7.78 (95% C.I. 1.33-45.5. No dose-response effect was observed according to smoking exposure during pregnancy and EAL. An association between secondhand smoking during pregnancy or breastfeeding was not observed. Conclusion: An association between maternal smoking and AAL in the offspring was restricted to women who have reported an intense exposure to tobacco smoke during pregnancy and breastfeeding.

  2. Oligomers Based on a Weak Hydrogen Bond Network: the Rotational Spectrum of the Tetramer of Difluoromethane

    Science.gov (United States)

    Feng, Gang; Evangelisti, Luca; Caminati, Walther; Cacelli, Ivo; Carbonaro, Laura; Prampolini, Giacomo

    2013-06-01

    Following the investigation of the rotational spectra of three conformers (so-called ``book'', ``prism'' and ``cage'') of the water hexamer, and of some other water oligomers, we report here the rotational spectrum of the tetramer of a freon molecule. The pulse jet Fourier transform microwave (pj-FTMW) spectrum of an isomer of the difluoromethane tetramer has been assigned. This molecular system is made of units of a relatively heavy asymmetric rotor, held together by a network of weak hydrogen bonds. The search of the rotational spectrum has been based on a high-level reference method, the CCSD(T)/CBS protocol. It is interesting to outline that the rotational spectrum of the water tetramer was not observed, probably because the minimum energy structures of this oligomer is effectively nonpolar in its ground states, or because of high energy tunnelling splittings. The rotational spectra of the monomer, dimer, trimer and tetramer of difluoromethane have been assigned in 1952, 1999, 2007, and 2013 (present work), with a decreasing time spacing between the various steps, looking then promising for a continuous and rapid extension of the size limits of molecular systems accessible to MW spectroscopy. C. Pérez, M. T. Muckle, D. P. Zaleski, N. A. Seifert, B. Temelso, G. C. Shields, Z. Kisiel, B. H. Pate, Science {336} (2012) 897. D. R. Lide, Jr., J. Am. Chem. Soc. {74} (1952) 3548. W. Caminati, S. Melandri, P. Moreschini, P. G. Favero, Angew. Chem. Int. Ed. {38} (1999) 2924. S. Blanco, S. Melandri, P. Ottaviani, W. Caminati, J. Am. Chem. Soc. {129} (2007) 2700.

  3. The ozone-climate penalty in the Midwestern U.S.

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    Jing, Ping; Lu, Zifeng; Steiner, Allison L.

    2017-12-01

    This paper investigates the relationship between ground-level ozone (O3) and temperature in the Midwestern U.S. during the period 1990-2015. From 1990 to 2015, the overall trend of 95th percentile temperature showed an increase of 0.04 K yr-1, while summertime 95th percentile O3 concentrations in the Midwest decreased at an average rate of 0.7 ppb yr-1 largely because NO2 concentrations decreased by more than 50%. The ozone-climate penalty, defined as the slope of O3 change with increasing temperature (ΔO3/ΔT), was by average 0.43 ppb K-1 less in 1999-2007 than in 1990-1998, indicating the early success of NOx emission controls. However, the slope did not continue to decrease in 2008-2015 despite further NOx emission reductions, and it increased more rapidly with increasing temperature (Δ2O3/ΔT2) by 0.03-0.09 ppb K-2 in most urban areas of the Midwest. This was accompanied by more frequent dry tropical (DT) weather in the Midwest since 2008. We find that O3 in DT weather was 12 ppb and 17 ppb higher than in non-DT weather in rural and urban areas, respectively. Furthermore, the 2008-2015 period experienced 8% more surface air stagnation days than in 1990-1998. This demonstrates that, in addition to the impact of warmer temperatures, the ozone-climate penalty could be aggravated by altered weather conditions under climate change. It will be challenging for Midwestern cities to attain the National Ambient Air Quality Standard for O3 if such conditions persist in the future, and future air quality improvements may require even greater efforts to reduce both NOx and VOC emissions in the Midwest.

  4. Demonstration of Aerosol Property Profiling by Multiwavelength Lidar Under Varying Relative Humidity Conditions

    Science.gov (United States)

    Veselovskii, I.; Whiteman, D. N.; Kolgotin, A.; Andrews, E.; Korenskii, M.

    2009-01-01

    During the months of July-August 2007 NASA conducted a research campaign called the Tropical Composition, Clouds and Climate Coupling (TC4) experiment. Vertical profiles of ozone were measured daily using an instrument known as an ozonesonde, which is attached to a weather balloon and launch to altitudes in excess of 30 km. These ozone profiles were measured over coastal Las Tablas, Panama (7.8N, 80W) and several times per week at Alajuela, Costa Rica (ION, 84W). Meteorological systems in the form of waves, detected most prominently in 100-300 in thick ozone layer in the tropical tropopause layer, occurred in 50% (Las Tablas) and 40% (Alajuela) of the soundings. These layers, associated with vertical displacements and classified as gravity waves ("GW," possibly Kelvin waves), occur with similar stricture and frequency over the Paramaribo (5.8N, 55W) and San Cristobal (0.925, 90W) sites of the Southern Hemisphere Additional Ozonesondes (SHADOZ) network. The gravity wave labeled layers in individual soundings correspond to cloud outflow as indicated by the tracers measured from the NASA DC-8 and other aircraft data, confirming convective initiation of equatorial waves. Layers representing quasi-horizontal displacements, referred to as Rossby waves, are robust features in soundings from 23 July to 5 August. The features associated with Rossby waves correspond to extra-tropical influence, possibly stratospheric, and sometimes to pollution transport. Comparison of Las Tablas and Alajuela ozone budgets with 1999-2007 Paramaribo and San Cristobal soundings shows that TC4 is typical of climatology for the equatorial Americas. Overall during TC4, convection and associated meteorological waves appear to dominate ozone transport in the tropical tropopause layer.

  5. Optimization ofRAS/BRAFMutational Analysis Confirms Improvement in Patient Selection for Clinical Benefit to Anti-EGFR Treatment in Metastatic Colorectal Cancer.

    Science.gov (United States)

    Santos, Cristina; Azuara, Daniel; Garcia-Carbonero, Rocio; Alfonso, Pilar Garcia; Carrato, Alfredo; Elez, Mª Elena; Gomez, Auxiliadora; Losa, Ferran; Montagut, Clara; Massuti, Bartomeu; Navarro, Valenti; Varela, Mar; Lopez-Doriga, Adriana; Moreno, Victor; Valladares, Manuel; Manzano, Jose Luis; Vieitez, Jose Maria; Aranda, Enrique; Sanjuan, Xavier; Tabernero, Josep; Capella, Gabriel; Salazar, Ramon

    2017-09-01

    In metastatic colorectal cancer (mCRC), recent studies have shown the importance to accurately quantify low-abundance mutations of the RAS pathway because anti-EGFR therapy may depend on certain mutation thresholds. We aimed to evaluate the added predictive value of an extended RAS panel testing using two commercial assays and a highly sensitive and quantitative digital PCR (dPCR). Tumor samples from 583 mCRC patients treated with anti-EGFR- ( n = 255) or bevacizumab- ( n = 328) based therapies from several clinical trials and retrospective series from the TTD/RTICC Spanish network were analyzed by cobas, therascreen , and dPCR. We evaluated concordance between techniques using the Cohen kappa index. Response rate, progression-free survival (PFS), and overall survival (OS) were correlated to the mutational status and the mutant allele fraction (MAF). Concordance between techniques was high when analyzing RAS and BRAF (Cohen kappa index around 0.75). We observed an inverse correlation between MAF and response in the anti-EGFR cohort ( P < 0.001). Likelihood ratio analysis showed that a fraction of 1% or higher of any mutated alleles offered the best predictive value. PFS and OS were significantly longer in RAS / BRAF wild-type patients, independently of the technique. However, the predictability of both PFS and OS were higher when we considered a threshold of 1% in the RAS scenario (HR = 1.53; CI 95%, 1.12-2.09 for PFS, and HR = 1.9; CI 95%, 1.33-2.72 for OS). Although the rate of mutations observed among techniques is different, RAS and BRAF mutational analysis improved prediction of response to anti-EGFR therapy. Additionally, dPCR with a threshold of 1% outperformed the other platforms. Mol Cancer Ther; 16(9); 1999-2007. ©2017 AACR . ©2017 American Association for Cancer Research.

  6. Validation of disability status, a claims-based measure of functional status for cancer treatment and outcomes studies.

    Science.gov (United States)

    Davidoff, Amy J; Gardner, Lisa D; Zuckerman, Ilene H; Hendrick, Franklin; Ke, Xuehua; Edelman, Martin J

    2014-06-01

    In prior research, we developed a claims-based prediction model for poor patient disability status (DS), a proxy measure for performance status, commonly used by oncologists to summarize patient functional status and assess ability of a patient to tolerate aggressive treatment. In this study, we implemented and validated the DS measure in 4 cohorts of cancer patients: early and advanced non-small cell lung cancers (NSCLC), stage IV estrogen receptor-negative (ER-) breast cancer, and myelodysplastic syndromes (MDS). SEER-Medicare data (1999-2007) for the 4 cohorts of cancer patients. Bivariate and multivariate logistic regression tested the association of the DS measure with designated cancer-directed treatments: early NSCLC (surgery), advanced NSCLC (chemotherapy), stage IV ER- breast cancer (chemotherapy), and MDS (erythropoiesis-stimulating agents). Treatment model fit was compared across model iterations. In both unadjusted and adjusted results, predicted poor DS was strongly associated with a lower likelihood of cancer treatment receipt in all 4 cohorts [early NSCLC (N=20,280), advanced NSCLC (N=31,341), stage IV ER- breast cancer (N=1519), and MDS (N=6058)] independent of other patient, contextual, and disease characteristics, as well as the Charlson Comorbidity Index. Inclusion of the DS measure into models already controlling for other variables did not significantly improve model fit across the cohorts. The DS measure is a significant independent predictor of cancer-directed treatment. Small changes in model fit associated with both DS and the Charlson Comorbidity Index suggest that unobserved factors continue to play a role in determining cancer treatments.

  7. "The lobbying strategy is to keep excise as low as possible" - tobacco industry excise taxation policy in Ukraine

    Science.gov (United States)

    2010-01-01

    Background Tobacco taxes are one of the most effective ways to reduce tobacco use. Transnational tobacco companies (TTCs) claim they wish to develop and secure excise systems that benefit both governments and the profitability of the companies themselves. The objective of the paper is to use the case of Ukraine, with its inconsistent history of excise tax changes in 1992-2008, to explore tobacco industry taxation strategies and tactics, and their implications for governmental revenues. Methods Details of tobacco industry policy on tobacco taxation in Ukraine were obtained by searching tobacco industry internal documents and various published reports. Results Even before entering the market in Ukraine, TTCs had made efforts to change the excise system in the country. In 1993-1994, TTCs lobbied the Ukrainian Government, and succeeded in achieving a lowering in tobacco tax. This, however, did not produce revenue increase they promised the Government. In 1996-1998, Ukrainian authorities increased excise several times, ignoring the wishes of TTCs, caused significant growth in revenue. Due to TTCs lobbying activities in 1999-2007 the tax increases were very moderate and it resulted in increased tobacco consumption in Ukraine. In 2008, despite the TTCs position, excise rates were increased twice and it was very beneficial for revenues. Conclusions The Framework Convention on Tobacco Control includes provisions both on tobacco taxation policy and on protection of public health policy from vested interests of tobacco industry. This paper provides arguments why tobacco taxation policy should also be protected from vested interests of tobacco industry. TTCs taxation strategy appears to be consistent: keep excise as low as possible. Apparent conflicts between TTCs concerning tax structures often hide their real aim to change tax structures for competing interests without increasing total tax incidence. Governments, that aim to reduce levels of tobacco use, should not allow

  8. Phylogeny of Dengue and Chikungunya viruses in Al Hudayda governorate, Yemen.

    Science.gov (United States)

    Ciccozzi, Massimo; Lo Presti, Alessandra; Cella, Eleonora; Giovanetti, Marta; Lai, Alessia; El-Sawaf, Gamal; Faggioni, Giovanni; Vescio, Fenicia; Al Ameri, Ranya; De Santis, Riccardo; Helaly, Ghada; Pomponi, Alice; Metwally, Dalia; Fantini, Massimo; Qadi, Hussein; Zehender, Gianguglielmo; Lista, Florigio; Rezza, Giovanni

    2014-10-01

    Yemen, which is located in the southwestern end of the Arabian Peninsula, is one of countries most affected by recurrent epidemics caused by emerging vector-borne viruses. Dengue virus (DENV) outbreaks have been reported with increasing frequency in several governorates since the year 2000, and the Chikungunya virus (CHIKV) has been also responsible of large outbreaks and it is now a major public health problem in Yemen. We report the results of the phylogenetic analysis of DENV-2 and CHIKV isolates (NS1 and E1 genes, respectively) detected in an outbreak occurred in Al-Hudayda in 2012. Estimates of the introduction date of CHIKV and DENV-2, and the phylogeographic analysis of DENV-2 are also presented. Phylogenetic analysis showed that the Yemen isolates of DENV belonged to the lineage 2 Cosmopolitan subtype, whereas CHIKV isolates from Yemen belonged to the ECSA genotype. All the CHIKV isolates from Yemen were statistically supported and dated back to the year 2010 (95% HPD: 2009-2011); these sequences showed an alanine in the aminoacid position 226 of the E1 protein. Phylogeographic analysis of DENV-2 virus showed that cluster 1, which included Yemen isolates, dated back to 2003 Burkina Faso strains (95% HPD 1999-2007). The Yemen, cluster dated back to 2011 (95% HPD 2009-2012). Our study sheds light on the global spatiotemporal dynamics of DENV-2 and CHIKV in Yemen. This study reinforces both the need to monitor the spread of CHIKV and DENV, and to apply significant measures for vector control. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Diabetes and obesity-related genes and the risk of neural tube defects in the national birth defects prevention study.

    Science.gov (United States)

    Lupo, Philip J; Canfield, Mark A; Chapa, Claudia; Lu, Wei; Agopian, A J; Mitchell, Laura E; Shaw, Gary M; Waller, D Kim; Olshan, Andrew F; Finnell, Richard H; Zhu, Huiping

    2012-12-15

    Few studies have evaluated genetic susceptibility related to diabetes and obesity as a risk factor for neural tube defects (NTDs). The authors investigated 23 single nucleotide polymorphisms among 9 genes (ADRB3, ENPP1, FTO, LEP, PPARG, PPARGC1A, SLC2A2, TCF7L2, and UCP2) associated with type 2 diabetes or obesity. Samples were obtained from 737 NTD case-parent triads included in the National Birth Defects Prevention Study during 1999-2007. Log-linear models were used to evaluate maternal and offspring genetic effects. After application of the false discovery rate, there were 5 significant maternal genetic effects. The less common alleles at the 4 FTO single nucleotide polymorphisms showed a reduction of NTD risk (for rs1421085, relative risk (RR) = 0.73 (95% confidence interval (CI): 0.62, 0.87); for rs8050136, RR = 0.79 (95% CI: 0.67, 0.93); for rs9939609, RR = 0.79 (95% CI: 0.67, 0.94); and for rs17187449, RR = 0.80 (95% CI: 0.68, 0.95)). Additionally, maternal LEP rs2071045 (RR = 1.31, 95% CI: 1.08, 1.60) and offspring UCP2 rs660339 (RR = 1.32, 95% CI: 1.06, 1.64) were associated with NTD risk. Furthermore, the maternal genotype for TCF7L2 rs3814573 suggested an increased NTD risk among obese women. These findings indicate that maternal genetic variants associated with glucose homeostasis may modify the risk of having an NTD-affected pregnancy.

  10. Transdisciplinaridade e educação intercultural: a formação do professor indígena Apinayé em perspectiva

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    Severina Alves de Almeida

    2014-02-01

    Full Text Available Neste artigo, refletimos sobre Transdisciplinaridade e Educação Intercultural, considerando o contexto Apinayé. Os Apinayé são um povo Indígena do norte do Estado do Tocantins. Os aspectos metodológicos estão voltados para uma concepção interdisciplinar, contemplando Estudos Teóricos e Pesquisa de Campo. Para o desenvolvimento do texto, temos duas fases que se complementam. Primeiro fazemos uma revisão da literatura atinente à temática abordada. Para os conceitos de Inter e Transdisciplinaridade, utilizamos as bases teóricas de D´Ambrósio (1997; Fazenda (2003; 2006; Nicolescu (2008; 2009; Damas (2009; Magalhães (2009; e Sommerman (2005. Para Educação Intercultural Ouellet (2002; Banks (1993; Maher (2005; 2006; e Grupioni (2001; 2003. Sobre os Apinayé Nimuendaju (1983; Da Matta (1976; e Albuquerque (1999; 2007; 2009. Acerca da pesquisa do tipo interdisciplinar: Vasconcelos (2009. Sobre Formação de Professores, Tardif (2002 e Pinho (2007. A pesquisa de campo se efetivou mediante uma etnografia com observação participante conforme Erikson (1984; e André (2000. Os dados, coletados, de forma qualitativa, foram gerados mediante diário e notas de campo. Os resultados apontam para uma realidade onde a Transdisciplinaridade se manifesta na prática pedagógica do Professor de Língua Materna Apinayé.

  11. The Association of Long-Term Exposure to Particulate Matter Air Pollution with Brain MRI Findings: The ARIC Study.

    Science.gov (United States)

    Power, Melinda C; Lamichhane, Archana P; Liao, Duanping; Xu, Xiaohui; Jack, Clifford R; Gottesman, Rebecca F; Mosley, Thomas; Stewart, James D; Yanosky, Jeff D; Whitsel, Eric A

    2018-02-16

    Increasing evidence links higher particulate matter (PM) air pollution exposure to late-life cognitive impairment. However, few studies have considered associations between direct estimates of long-term past exposures and brain MRI findings indicative of neurodegeneration or cerebrovascular disease. Our objective was to quantify the association between brain MRI findings and PM exposures approximately 5 to 20 y prior to MRI in the Atherosclerosis Risk in Communities (ARIC) study. ARIC is based in four U.S. sites: Washington County, Maryland; Minneapolis suburbs, Minnesota; Forsyth County, North Carolina; and Jackson, Mississippi. A subset of ARIC participants underwent 3T brain MRI in 2011-2013 (n=1,753). We estimated mean exposures to PM with an aerodynamic diameter less than 10 or 2.5μm (PM 10 and PM 2.5 ) in 1990-1998, 1999-2007, and 1990-2007 at the residential addresses of eligible participants with MRI data. We estimated site-specific associations between PM and brain MRI findings and used random-effect, inverse variance-weighted meta-analysis to combine them. In pooled analyses, higher mean PM 2.5 and PM 10 exposure in all time periods were associated with smaller deep-gray brain volumes, but not other MRI markers. Higher PM 2.5 exposures were consistently associated with smaller total and regional brain volumes in Minnesota, but not elsewhere. Long-term past PM exposure in was not associated with markers of cerebrovascular disease. Higher long-term past PM exposures were associated with smaller deep-gray volumes overall, and higher PM 2.5 exposures were associated with smaller brain volumes in the Minnesota site. Further work is needed to understand the sources of heterogeneity across sites. https://doi.org/10.1289/EHP2152.

  12. Is It Necessary Managing Carnivores to Reverse the Decline of Endangered Prey Species? Insights from a Removal Experiment of Mesocarnivores to Benefit Demographic Parameters of the Pyrenean Capercaillie.

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    Rubén Moreno-Opo

    Full Text Available Mesopredator control has long been used to alleviate the effect of elevated predation pressure on vulnerable, threatened or valuable species. However, the convenience of using mesopredator controls is technically questionable and scientifically-sound research is therefore required to evaluate the impact of predation on prey case by case. In this study we evaluated the effect of the alteration of terrestrial mesopredator dynamics on the demographic parameters of a relict capercaillie Tetrao urogallus aquitanicus population currently in decline for which the impact of predation has not previously been assessed. We used a six-year mesocarnivore removal experiment (2008-2013 together with seven-years of previous demographic information on capercaillies (1999-2007 within a before-after control-impact (BACI design to evaluate the effect of mesocarnivore removal on capercaillie demographic parameters and on spatial behaviour of the most frequent predatory mesocarnivores of the capercaillie (Martes spp. and red fox Vulpes vulpes. Using a dynamic site-occupancy approach, the reduction of mesocarnivore population levels as a result of removal was clear for marten species, mainly during key months for capercaillie reproduction, but not for the red fox. Our results show that the breeding success of capercaillies was enhanced in areas where carnivores were removed and was inversely related to the occupation level of the studied mesocarnivores, although being only significant for Martes spp. Moreover, capercaillie predation rates were lower and adult survival seemingly higher in treatment during the removal phase. Cost-effective, long-term management interventions to ensure the recovery of this threatened capercaillie population are discussed in the light of the results. At our study area, the decision for implementing predation management should be included within a broader long-term conservation perspective. In this regard, a more feasible and sustainable

  13. Detection of change in vegetation in the surrounding Desert areas of Northwest China and Mongolia with multi-temporal satellite images

    Science.gov (United States)

    Han, Kyung-Soo; Park, Youn-Young; Yeom, Jong-Min

    2015-05-01

    Vegetation monitoring is an important step in developing a better understanding of land use and its changes, due to the sensitivity of surface vegetation to changes in the global climate and environment. In this study, normalized difference vegetation index (NDVI) of the area surrounding the Gobi Desert in North Asia was multi-temporally interpreted by analyzing time-series Satellite Pour l'Observation de la Terre (SPOT) Vegetation (VGT) data, over a roughly nine-year period from January 1999 to November 2007. The study area was classified into eight classes, and compared to classified Moderate resolution Imaging Spectrometer (MODIS) global land-cover data to select desertification-sensitive areas. The study focused on three classes (barren land, open shrubland, grassland) due to their high sensitivity to climate change. The results showed significant extension of the barren land class from 1992 to 1999, with 47.8% of the open shrubland transformed into barren land. Among five terms (1999-2003, 2003-2005, 2005-2007, 1999-2005, 1999-2007) which are carefully selected from variations of the annual NDVI mean for each class over nine years, significant changes were observed for barren land from 1999-2003, and for open shrubland and grassland from 2005-2007. An analysis of the positive change (the change from sparse vegetation to dense vegetation) and negative change (or desertification) was conducted over the study period; the number of pixels corresponding to a positive change for barren land was similar to the number of negative change pixels. Human activity and afforestation over the study area were also captured in multitemporal satellite imagery. For open shrubland and grassland, the negative change area was bigger than the positive change area. Precipitation data over the nine-year period exhibited a pattern similar to that for the vegetation data, as expected.

  14. Foodborne botulism in southwest Romania during the post-communism period 1990-2007.

    Science.gov (United States)

    Neghina, Adriana Maria; Marincu, Iosif; Moldovan, Roxana; Iacobiciu, Ioan; Neghina, Raul

    2010-02-01

    This study was a retrospective investigation of botulism cases over a period of 18 years following major political and economic changes, addressing the question of whether this disease is still an important health concern in southwest Romania. The medical records of botulism cases were used as the source of data. Patients from five southwest Romanian counties were hospitalized at Victor Babes Hospital of Infectious Diseases in Timisoara during the period 1990-2007. The median annual incidence of botulism cases in southwest Romania decreased from 0.1 per 100 000 persons during 1990-1998, to 0.05 per 100 000 persons during 1999-2007. Most of the cases (18.6%) were diagnosed in 1990, immediately following the communism period. The median age of the patients was 38 years (range 16-73 years); 24 (55.8%) were male; the case fatality rate was 2.3%. A significantly higher incidence rate of 2.7 cases per 100 000 persons occurred in rural areas, even though most of the cases (53.5%) were inhabitants of urban areas. The clinical pattern included: difficulty swallowing (79.1%), double and/or blurred vision (69.8%), dry mouth (60.5%), drooping eyelids (51.2%), vomiting (39.5%), mydriasis (37.2%), constipation (27.9%), abdominal pain (23.3%), and slurred speech (18.6%). All cases were attributed to contaminated food sources, mainly home-prepared traditional pork products. Although the botulism cases decreased over the study period in southwest Romania, this life-threatening disease continues to be an important concern. A strategy addressing individual behaviors in the home is needed to improve food safety. Copyright 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  15. Death in media

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    Pavićević Aleksandra

    2010-01-01

    Full Text Available This paper discusses the role of media in a construction of public image speech and presentation of death. The main research questions could be posed as follows: does the media discourse confirm a thesis about modern society as the one which intensely avoids encounter with Death, or does it defy it? Frequent images or hints of death in visual media in films informative and entertainment programs-suggest certain changes related to this issue in the past few decades. This analysis focuses on printed media hence the paper assesses numerous issues of the daily journal Politika from 1963, 1972, 1973, 1979, 1985, 1991, 1995, 1999, 2007 and 2008, as well as some other daily journals after 2000. The analysis confirms a strong connection between the current political systems and ideology and speech about death. In addition, it reveals a political usage of this event but also speaks up about cultural and historical models, underlying all other constructions. During the 1960's and 1970's, the presentations, including the speech about death relied on the traditional understandings about inevitability of death and dying, and alternatively on atheistic beliefs related to the progress and wellbeing of the society. In this particular discourse, death was present to a limited degree, serving primarily to glorify socialist order. The end of the 1970's witnessed an increase in the glorification of the death, correlated with the decrease of the dominant political ideology. On the other hand, the 1990's brought about more presence of the national and religious symbolism and glorification of the dead as heroes. After 2000, mercantilism is evident throughout the media. All of the media broadcast drastic images of death and dead, thus providing an answer to the posed question at the beginning of this paper about the relationship of the modern society towards death but nevertheless, this still leaves out many implicit consequences and possible meanings.

  16. Role of active and passive smoking in high-risk human papillomavirus infection and cervical intraepithelial neoplasia grade 2 or worse.

    Science.gov (United States)

    Feng, Rui Mei; Hu, Shang Ying; Zhao, Fang Hui; Zhang, Rong; Zhang, Xun; Wallach, Asya Izraelit; Qiao, You Lin

    2017-09-01

    We performed a pooled analysis to examine cigarette smoking and household passive smoke exposure in relation to the risk of human papillomavirus (HPV) infection and cervical intraepithelial neoplasia grade 2+ (CIN2+). Data were pooled from 12 cross-sectional studies for cervical cancer screenings from 10 provinces of China in 1999-2007. A total of 16,422 women were analyzed, along with 2,392 high-risk-HPV (hr-HPV) positive women and 381 CIN2+ cases. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression models controlling for sexual and non-sexual confounding factors. There was an excess risk between active smoking and hr-HPV infection and CIN2+. Adjusted OR for ever smokers vs. never smokers was 1.45 (95% CI=1.10-1.91), for hr-HPV infection and 1.89 (95% CI=1.03-3.44), for CIN2+. Passive smoking had a slightly increased risk on the hr-HPV infection with adjusted OR 1.11 (1.00-1.24), but no statistical association was observed between passive smoke exposure and CIN2+. Compared with the neither active nor passive smokers, both active and passive smokers had a 1.57-fold (95% CI=1.14-2.15) increased risk of HPV infection and a 1.99-fold (95% CI=1.02-3.88) risk of CIN2+. Our large multi-center cross-sectional study found active smoking could increase the risk of overall hr-HPV infection and CIN2+ adjusted by passive smoking and other factors. Passive smoking mildly increased the risk of HPV infection but not the CIN2+. An interaction existed between passive tobacco exposure and active smoking for hr-HPV infection and the CIN2+. Copyright © 2017. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology

  17. The Conference in the Moscow Kremlin State Museums “Historical Weapons in Museums and Private Collections”

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    Sergey P. Orlenko

    2017-03-01

    Full Text Available In November 2016 in the Moscow Kremlin State Historical and Cultural Museum and Heritage Site in the framework of events dedicated to the 210th anniversary of the Armoury Chamber museum, an international conference “Historical weapons in museums and private collections”. This scientific forum continued the tradition of conferences held in the Moscow Kremlin Museums in 1999-2007. The participants of this forum discussed a number of priority topics for the studies of the weapon collection history in the Kremlin. These topics were relevant to the national and world studies of weaponology as a whole. In addition to general issues of the history of arms and armour, a number of reports were devoted to the functioning of the historical centers of arms production, weapons collections in Russia and abroad, particular items, as well as the activities of gunsmiths, designers of weapons. The conference was attended by representatives of more than 20 Russian and foreign museums, 14 academic and university research centers and institutions, private collectors and lovers of ancient weapons. During the three days of the conference 36 reports were presented and discussed. Organizers of the conference highlighted a number of reports including new attributions of the items from the Kremlin collections. The conference program is available on the official website of the Moscow Kremlin State Museums. The conference results were published as a collection of proceedings. The weaponology forum in the Kremlin will be held annually. The Moscow Kremlin Museums invite researchers of historical weapons, museum employees and collectors to the active cooperation.

  18. The nine-year sustained cost-containment impact of swiss pilot physicians-pharmacists quality circles.

    Science.gov (United States)

    Niquille, Anne; Ruggli, Martine; Buchmann, Michel; Jordan, Dominique; Bugnon, Olivier

    2010-04-01

    Six pioneer physicians-pharmacists quality circles (PPQCs) located in the Swiss canton of Fribourg (administratively corresponding to a state in the US) were under the responsibility of 6 trained community pharmacists moderating the prescribing process of 24 general practitioners (GPs). PPQCs are based on a multifaceted collaborative process mediated by community pharmacists for improving compliance with clinical guidelines within GPs' prescribing practices. To assess, over a 9-year period (1999-2007), the cost-containment impact of the PPQCs. The key elements of PPQCs are a structured continuous quality improvement and education process; local networking; feedback of comparative and detailed data regarding costs, drug choice, and frequency of prescribed drugs; and structured independent literature review for interdisciplinary continuing education. The data are issued from the community pharmacy invoices to the health insurance companies. The study analyzed the cost-containment impact of the PPQCs in comparison with GPs working in similar conditions of care without particular collaboration with pharmacists, the percentage of generic prescriptions for specific cardiovascular drug classes, and the percentage of drug costs or units prescribed for specific cardiovascular drugs. For the 9-year period, there was a 42% decrease in the drug costs in the PPQC group as compared to the control group, representing a $225,000 (USD) savings per GP only in 2007. These results are explained by better compliance with clinical and pharmacovigilance guidelines, larger distribution of generic drugs, a more balanced attitude toward marketing strategies, and interdisciplinary continuing education on the rational use of drugs. The PPQC work process has yielded sustainable results, such as significant cost savings, higher penetration of generics and reflection on patient safety, and the place of "new" drugs in therapy. The PPQCs may also constitute a solid basis for implementing more

  19. The effect of increasing exports on industrial energy intensity in China

    International Nuclear Information System (INIS)

    Zheng Yingmei; Qi Jianhong; Chen Xiaoliang

    2011-01-01

    Given China's heavy reliance on fuel energy and the dominance of its industrial sector in the economy, improving energy efficiency remains one of the practical means for the country to decrease energy intensity and to fulfill its commitment made at the Copenhagen Climate Change Conference to achieve a 40-45 percent reduction in CO 2 emission intensity by 2020. This study investigates the impact of exports on industrial energy intensity to explore the possibility of reducing energy intensity through greater exports. A panel varying-coefficient regression model with a dataset of China's 20 industrial sub-sectors over 1999-2007 suggests that in general, greater exports aggravate energy intensity of the industrial sector and that great divergences exist in the impact of exports on energy intensity across sub-sectors. A panel threshold model further estimates the thresholds for the major determinants of energy intensity: exports, input in technological innovations, and Foreign Direct Investment (FDI) intensity. Given the great differences in specific sub-sector characteristics and the changing roles played by different factors across sub-sectors, there is no general export policy that would work for all sub-sectors in reducing sub-sector energy intensity. Instead, policies and measures aiming to encourage more efficient use of energy should take into full consideration the characteristics and situations of individual sub-sectors. - Research highlights: → We examine the impact of exports on industrial energy intensity in China. → Greater exports increase industrial energy intensity as a whole. → Divergences exist in the impact of exports on energy intensity across sub-sectors. → China should discard policies encouraging exports at the cost of energy efficiency. → Export policy to reduce energy intensity should cater to sub-sector characteristics.

  20. Modeling the contributions of ring, tail, and magnetopause currents to the corrected Dst index

    Science.gov (United States)

    Asikainen, T.; Maliniemi, V.; Mursula, K.

    2010-12-01

    We present a new semiempirical model describing the contributions of the ring, tail, and magnetopause currents to the Dcx index. We use the isotropic boundary (IB) location of energetic particles measured by the NOAA/POES satellites, as a proxy for the tail current strength. Using local linear regression, we derive the model parameters and their functional dependencies on solar wind and interplanetary magnetic field parameters and on IB latitude. The model gives the ring, tail, and magnetopause current contributions for the whole time interval 1999-2007, performing roughly equally well during all activity levels. We find that the coefficient of proportionality between the square root of solar wind pressure and the magnetopause current contribution is larger than in earlier estimates. Ring current decay time is found to decrease with increasing solar wind electric field and dynamic pressure. We estimate the average quiet time level of the combined ring and tail (magnetopause) current contributions to Dcx to be roughly -7 nT (+13 nT). The average tail current contribution is found to be about 34% of the Dcx index, which is somewhat larger than previous estimates based on smaller-intensity storms. For individual storms the tail current contribution can reach up to -160 nT (about 40%-60% of the pressure corrected Dcx). The present model agrees well with earlier results for individual storms based on detailed dynamical models of the magnetosphere. Our work demonstrates that the different current contributions to Dcx during both active and quiet time intervals can be reliably estimated using solar wind observations and isotropic boundary location.

  1. Accidents in the greenhouse-construction industry of SE Spain.

    Science.gov (United States)

    Pérez-Alonso, José; Carreño-Ortega, Angel; Vázquez-Cabrera, Fernando J; Callejón-Ferre, Angel Jesús

    2012-01-01

    This work analyses the labour accidents in the greenhouse-construction industry of SE Spain for the period 1999-2007 through a sample of 180 accident reports. The accidents were characterised by studying 5 variables in order to know the day of the week in which the accident occurred, the hour of the day of the accident, type of accident, the region of Spain in which the accident happened, and the resulting injury. The data characterising the accidents were submitted to a descriptive multiple-correspondence analysis. The incidence of accidents in the greenhouse-construction industry presented a high mean value of 15133.7 per 100,000 workers per year. The days with the greatest incidence of accidents were Thursday and Monday, while the period of greatest number of accidents occurred in the first 4h of the workday. No significant correspondence was found between the day of the week, the hour of the day, or any of the other 3 variables studied. The types of accidents with most frequency were: cuts, punctures, contact with hard or rough material, overexertion, and falls from one level to another. The most affected parts of the anatomy were the eyes, thorax, back, sides, lower legs, and feet. The most common types of injury were bone fractures, twists and sprains, distended muscles, contusions, and being crushed. The study calls attention to the high number of accidents at work, which needs to be corrected by fulfilment of safety regulations at work, on the part of the company. Finally, recommendations are made to correct this situation of high number of accidents at work. Copyright © 2011 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  2. Racial/ethnic differences in survival of United States children with birth defects: a population-based study.

    Science.gov (United States)

    Wang, Ying; Liu, Gang; Canfield, Mark A; Mai, Cara T; Gilboa, Suzanne M; Meyer, Robert E; Anderka, Marlene; Copeland, Glenn E; Kucik, James E; Nembhard, Wendy N; Kirby, Russell S

    2015-04-01

    To examine racial/ethnic-specific survival of children with major birth defects in the US. We pooled data on live births delivered during 1999-2007 with any of 21 birth defects from 12 population-based birth defects surveillance programs. We used the Kaplan-Meier method to calculate cumulative survival probabilities and Cox proportional hazards models to estimate mortality risk. For most birth defects, there were small-to-moderate differences in neonatal (<28 days) survival among racial/ethnic groups. However, compared with children born to non-Hispanic white mothers, postneonatal infant (28 days to <1 year) mortality risk was significantly greater among children born to non-Hispanic black mothers for 13 of 21 defects (hazard ratios [HRs] 1.3-2.8) and among children born to Hispanic mothers for 10 of 21 defects (HRs 1.3-1.7). Compared with children born to non-Hispanic white mothers, a significantly increased childhood (≤ 8 years) mortality risk was found among children born to Asian/Pacific Islander mothers for encephalocele (HR 2.6), tetralogy of Fallot, and atrioventricular septal defect (HRs 1.6-1.8) and among children born to American Indian/Alaska Native mothers for encephalocele (HR 2.8), whereas a significantly decreased childhood mortality risk was found among children born to Asian/Pacific Islander mothers for cleft lip with or without cleft palate (HR 0.6). Children with birth defects born to non-Hispanic black and Hispanic mothers carry a greater risk of mortality well into childhood, especially children with congenital heart defect. Understanding survival differences among racial/ethnic groups provides important information for policy development and service planning. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Direct-to-consumer genomics on the scales of autonomy.

    Science.gov (United States)

    Vayena, Effy

    2015-04-01

    Direct-to-consumer (DTC) genetic services have generated enormous controversy from their first emergence. A dramatic recent manifestation of this is the Food and Drug Administration's (FDA) cease and desist order against 23andMe, the leading provider in the market. Critics have argued for the restrictive regulation of such services, and even their prohibition, on the grounds of the harm they pose to consumers. Their advocates, by contrast, defend them as a means of enhancing the autonomy of those same consumers. Autonomy emerges as a key battle-field in this debate, because many of the 'harm' arguments can be interpreted as identifying threats to autonomy. This paper assesses whether DTC genomic services are a threat to, or instead, an enhancement of, personal autonomy. It deploys Joseph Raz's account of personal autonomy, with its emphasis on choice from a range of valuable options. It then seeks to counter claims that DTC genomics threatens autonomy because it involves manipulation in contravention of consumers' independence or because it does not generate valuable options which can be meaningfully engaged with by consumers. It is stressed that the value of the options generated by DTC genomics should not be judged exclusively from the perspective of medical actionability, but should take into consideration plural utilities. Finally, the paper ends by broaching policy recommendations, suggesting that there is a strong autonomy-based argument for permitting DTC genomic services, and that the key question is the nature of the regulatory conditions under which they should be permitted. The discussion of autonomy in this paper helps illuminate some of these conditions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  4. Comprehension and Data-Sharing Behavior of Direct-To-Consumer Genetic Test Customers.

    Science.gov (United States)

    McGrath, Scott P; Coleman, Jason; Najjar, Lotfollah; Fruhling, Ann; Bastola, Dhundy R

    2016-01-01

    The aim of this study was to evaluate current direct-to-consumer (DTC) genetic customers' ability to interpret and comprehend test results and to determine if honest brokers are needed. One hundred and twenty-two customers of the DTC genetic testing company 23andMe were polled in an online survey. The subjects were asked about their personal test results and to interpret the results of two mock test cases (type 2 diabetes and multiple sclerosis), where results were translated into disease probability for an individual compared to the public. When asked to evaluate the risk, 72.1% correctly assessed the first case and 77% were correct on the second case. Only 23.8% of those surveyed were able to interpret both cases correctly. x03C7;2 and logistic regression were used to interpret the results. Participants who took the time to read the DTC test-provided supplemental material were 3.93 times (p = 0.040) more likely to correctly interpret the test results than those who did not. The odds for correctly interpreting the test cases were 3.289 times (p = 0.011) higher for those who made more than USD 50,000 than those who made less. Survey results were compared to the Health Information National Trends Survey (HINTS) phase 4 cycle 3 data to evaluate national trends. Most of the subjects were able to correctly interpret the test cases, yet a majority did not share their results with a health-care professional. As the market for DTC genetic testing grows, test comprehension will become more critical. Involving more health professionals in this process may be necessary to ensure proper interpretations. © 2016 S. Karger AG, Basel.

  5. Risky business: risk perception and the use of medical services among customers of DTC personal genetic testing.

    Science.gov (United States)

    Kaufman, David J; Bollinger, Juli M; Dvoskin, Rachel L; Scott, Joan A

    2012-06-01

    Direct-to-consumer genetic testing has generated speculation about how customers will interpret results and how these interpretations will influence healthcare use and behavior; however, few empirical data on these topics exist. We conducted an online survey of DTC customers of 23andMe, deCODEme, and Navigenics to begin to address these questions. Random samples of U.S. DTC customers were invited to participate. Survey topics included demographics, perceptions of two sample DTC results, and health behaviors following DTC testing. Of 3,167 DTC customers invited, 33% (n = 1,048) completed the survey. Forty-three percent of respondents had sought additional information about a health condition tested; 28% had discussed their results with a healthcare professional; and 9% had followed up with additional lab tests. Sixteen percent of respondents had changed a medication or supplement regimen, and one-third said they were being more careful about their diet. Many of these health-related behaviors were significantly associated with responses to a question that asked how participants would perceive their colon cancer risk (as low, moderate, or high) if they received a test result showing an 11% lifetime risk, as compared to 5% risk in the general population. Respondents who would consider themselves to be at high risk for colon cancer were significantly more likely to have sought information about a disease (p = 0.03), discussed results with a physician (p = 0.05), changed their diet (p = 0.02), and started exercising more (p = 0.01). Participants' personal health contexts--including personal and family history of disease and quality of self-perceived health--were also associated with health-related behaviors after testing. Subjective interpretations of genetic risk data and personal context appear to be related to health behaviors among DTC customers. Sharing DTC test results with healthcare professionals may add perceived utility to the tests.

  6. Multimodaalse suhtlusakti struktuur ja tähenduse kujunemine mitme osalejaga suhtlussituatsioonis

    Directory of Open Access Journals (Sweden)

    Dmitri Kulakov

    2017-05-01

    Full Text Available "Structure of multimodal communicative acts and formation of meaning in multiparty communication situations" The article elaborates on the structure of a multimodal act, and thereby also the underlying cognitive processes. The current paper presents a study on the basis of empirical data concerning utilization of communication modalities on transmission and successful reception of the meaning in a situation with concurrent presence of objects in the communicative space. The analyzed materials originate from corpora of audio- and videotape recordings of native inhabitants from shore villages of the lake Peipus (Research Group on Multimodal Communication, University of Tartu. The method of microanalysis of video recordings as well as theories of multimodal communication were employed in the research. The method and theoretical term base were combined pursuant to the data under analysis. Five people participated in the communication situation and the conversation took place in Russian. The analysis encompasses identification of the conversational topic and description of the physical space, movements and linguistic aspects. Artikkel toob esile, millised on mitme osalejaga multimodaalses suhtlussituatsioonis seosed modaalsuste vahel tähenduste kujundamisel ja vastuvõtmisel. Teoreetiliselt lähtume suhtlusakti struktuuri analüüsist ning keskendume multimodaalsele kommunikatsioonile. Näitame, millisel viisil on mitme osalejaga suhtluses võimalik kasutada osalejate kommunikatiivset potentsiaali, et edastada ja vastu võtta tähendusi ning sooritada konkreetseid suhtlustegevusi. Analüüs toob välja osalejate verbaalsete ja mitteverbaalsete suhtlusmodaalsuste rolli tähenduse konstrueerimisel ja üksteise mõistmisel, kui kujutatakse referenti või osutatakse sellele. Andmed pärinevad Peipsi järve rannakülade elanike suhtlussituatsioonide audio- ja videosalvestuste korpusest, mis on lindistatud loomulikus situatsioonis välitingimustes

  7. Understanding the promises and premises of online health platforms

    Directory of Open Access Journals (Sweden)

    José Van Dijck

    2016-06-01

    Full Text Available This article investigates the claims and complexities involved in the platform-based economics of health and fitness apps. We examine a double-edged logic inscribed in these platforms, promising to offer personal solutions to medical problems while also contributing to the public good. On the one hand, online platforms serve as personalized data-driven services to their customers. On the other hand, they allegedly serve public interests, such as medical research or health education. In doing so, many apps employ a diffuse discourse, hinging on terms like “sharing,” “open,” and “reuse” when they talk about data extraction and distribution. The analytical approach we adopt in this article is situated at the nexus of science and technology studies, political economy, and the sociology of health and illness. The analysis concentrates on two aspects: datafication (the use and reuse of data and commodification (a platform’s deployment of governance and business models. We apply these analytical categories to three specific platforms: 23andMe, PatientsLikeMe, and Parkinson mPower. The last section will connect these individual examples to the wider implications of health apps’ data flows, governance policies, and business models. Regulatory bodies commonly focus on the (medical safety and security of apps, but pay scarce attention to health apps’ techno-economic governance. Who owns user-generated health data and who gets to benefit? We argue that it is important to reflect on the societal implications of health data markets. Governments have the duty to provide conceptual clarity in the grand narrative of transforming health care and health research.

  8. Consumers' use of web-based information and their decisions about multiplex genetic susceptibility testing.

    Science.gov (United States)

    Kaphingst, Kimberly A; McBride, Colleen M; Wade, Christopher; Alford, Sharon Hensley; Brody, Lawrence C; Baxevanis, Andreas D

    2010-09-29

    Few data exist to inform concerns raised by online direct-to-consumer marketing of genetic susceptibility tests, such as those offered by commercial entities like 23andme, Navigenics, and DNA Direct. The Multiplex Initiative, a population-based study of healthy adults, provides the first opportunity to evaluate how use of a Web-based decision tool that conveyed information about a genetic susceptibility test influenced individuals' test decisions. To inform the ongoing debate over whether individuals offered genetic susceptibility testing without the involvement of a health care provider (eg, through direct-to-consumer testing) can make informed decisions about testing when guided by online decision aids. Participants were 526 members of a large health maintenance organization aged 25 to 40 years old who visited a study website. Multivariate logistic regression models were tested to examine the association of website usage with downstream test decisions. Participants viewed an average of 2.9 of the 4 pages introducing the multiplex test, 2.2 of the 8 pages describing the health conditions, and 3.2 of the 15 pages describing the genes. For each page viewed, participants were more likely to describe their decision-making as easy (odds ratio [OR] 1.04, 95% confidence interval [CI] 1.01-1.07) and to decide to be tested (OR 1.08, 95% CI 1.05-1.11). Healthy adults in this study perceived Web-based genomic information presented using evidence-based communications approaches to be helpful in supporting both decisions to test and not to test. Continued research is needed to ensure that these results generalize to target groups with lower literacy and less Internet savvy.

  9. Molecular data raise the possibility of cryptic species in the Brazilian endemic prawn Macrobrachiumpotiuna (Decapoda, Palaemonidae

    Directory of Open Access Journals (Sweden)

    Fabrício L de Carvalho

    2013-09-01

    Full Text Available A recent taxonomic revision indicated that Macrobrachiumpotiuna, an endemic prawn in Brazilian freshwater drainages, exhibits wide morphological variability along its limited geographical distribution. However, in some cases, taxonomic doubts at the species level have no clear morphological resolution. Considering that no molecular data of M. potiuna along its distribution were available to provide a complete and integrated overview, we analyzed 21 partial sequences (531 bp from the mitochondrial 16S rRNA gene of M. potiuna and 9 sequences from outgroup species, by maximum likelihood and parsimony, in order to investigate the possibility of the existence of cryptic species, within the morphologically based M. potiuna. The topologies obtained revealed that M. potiuna represents a monophyletic clade. Nevertheless, two clades supported by both analyses were formed within the M. potiuna taxon. The mean genetic divergence between these two groups was 0.044 ± 0.007, and within each group (i.e., M. potiuna "sensu stricto" andM. potiuna "Affinis-Clade" the divergences were 0.010 ± 0.003 and 0.028 ± 0.005, respectively. As far as we know, this is the first report to show a genetic separation between populations of prawns with abbreviated larval development in South American drainages. Pending additional analysis, to propose a conclusive inference, the existence of these distinct genetic groups must be considered in future studies with the morphologically based M. potiuna. In addition, we extended the known northern distribution with a record from the state of Bahia.

  10. De-institutionalisation and trans-institutionalisation - changing trends of inpatient care in Norwegian mental health institutions 1950-2007

    Directory of Open Access Journals (Sweden)

    Kolstad Arnulf

    2009-12-01

    Full Text Available Abstract Background Over the last decades mental health services in most industrialised countries have been characterised by de-institutionalisation and different kinds of redistribution of patients. This article will examine the historical trends in Norway over the period 1950-2007, identify the patterns of change in service settings and discuss why the mental health services have been dramatically transformed in less than sixty years. Methods The presentation of the trends in the Norwegian mental health services and the outline of the major changes in the patterns of inpatient care over the period 1950-2007 is founded on five indicators: The average inpatient population, the number of discharges during a year, the average length of stay, the number of beds or places, and the occupancy rate (average inpatient population/beds. Data are reported by institutional setting. Multiple sources of data are used. In some cases it has been necessary to interpolate data due to missing data. Results New categories of institutions were established and closed during the 57 years period. De-hospitalisation started in Norway in the early 1970s, de-institutionalisation in general 15 years later. Six distinct periods are identified: The asylum period (-1955, institutionalisation and trans-institutionalisation (1955-65, stabilisation and onset of de-hospitalisation (1965-75, de-hospitalisation (1975-87, from nursing homes to community-based services (1988-98, and the national mental health program (1999-2007. There has been a significant reduction in the number of beds and in the average in-patient population. The average length of stay in institutions has been continuously reduced since 1955. The number of patients actually treated in psychiatric institutions has increased significantly. Accessibility, quality of care and treatment for most patients has improved during the period. The mental health system in Norway has recently been evaluated as better than the

  11. In Pursuit of Nearshore Wave Characteristics- Implementation and Validation of a Shallow Water Correction for High Frequency Radars along the New Jersey Coast

    Science.gov (United States)

    Livermont, E. A.

    2014-12-01

    Within the U.S., coastal ocean current mapping with HF radar has matured to the point where it is now considered an essential component of regional ocean observing systems. A Mid-Atlantic HF radar network now provides high-resolution coverage within five localized networks, which are linked together to cover the full range of the Mid-Atlantic coast. While the primary focus of these networks has been on offshore current mapping observations, a long-term objective has been to develop and evaluate nearshore waves and currents. Of particular interest is the height of ocean waves that play a crucial role in engineering projects, ship navigation and design, vessel traffic control as well as shoreline protection, beach erosion, and mitigation of oil spills and ocean pollution. The radars owned by Rutgers University cover the coastline of New Jersey at multiple frequencies from 4.5 to 25 MHz. Their echoes contain information on both currents and waves from deep water up into the shallow coastal zone, providing an excellent archive for this study. Radar sea-echo spectra consist of dominant first-order peaks surrounded with lower-energy second-order structures. Present analysis methods assume that the waves do not interact with the ocean floor. The assumption of deep water is often invalid close to the coast and for broad continental shelves, and is particularly inadequate to describe the second-order sea-echo used to give information on ocean waves. Additionally, second-order echo is often only visible above the noise floor at close ranges. In this paper, a shallow water spectral theory is implemented at four locations on the New Jersey coast- Strathmere, Wildwood, Brant Beach, and Sea Bright. The corrected wave characteristics extracted from the HF radars were then compared to several in situ wave measurements. The first three sites—Strathmere, Wildwood and Brant Beach—were validated against two long-term (1999-2007) wave gauges deployed by Stevens Institute of

  12. Estudo da incidência de coledocolitíase em pacientes com colecistite calculosa aguda e crônica submetidos à colecistectomia vídeolaparoscópica

    Directory of Open Access Journals (Sweden)

    Sidney Moreno Gil

    Full Text Available OBJETIVO: Avaliar a incidência da coledocolitiase em pacientes submetidos à colecistectomia laparoscópica, portadores de colecistopatia calculosa aguda e crônica. O presente estudo, também, analisa se a era laparoscópica modificou a incidência e a história natural da litíase da via biliar quando compara os dados da literatura com os índices do Grupo estudado. MÉTODO: O estudo foi realizado em um Grupo de 946 pacientes, distribuídos em Grupo A de 214 pacientes de 1991-1995 e Grupo B de 732 pacientes de 1999-2007 colecistectomizados pelo método laparoscópico. O critério diagnóstico de coledocolitíase foi estabelecido por colangiofluoroscopia de rotina em todas as operações. RESULTADOS: A incidência total de coledocolitiase no Grupo A de 9,8% e no B de 5,8% não mostram diferença estatística significativa entre si e com a literatura mundial (p=0,08.Nos pacientes operados por colecistite aguda também não se observou diferença estatística entre o grupo A e B na incidência de litíase da via biliar( p=0,8. A análise dos dados nos pacientes operados por colecistite crônica revela uma taxa de coledocolitíase menor no Grupo B de 3,7% com significância estatística do que no A de 8,4% p=0,03. CONCLUSÃO: O presente estudo revela uma diminuição expressiva na incidência de coledocolitiase no Grupo B em relação ao A e a literatura mundial quando a indicação cirúrgica ocorre na fase não complicada da doença litiásica biliar. O estudo também demonstra um aumento significativo na indicação da colecistectomia laparoscópica eletiva mais precoce no Grupo B como já observado em diversas publicações da literatura médica.

  13. Phase shifts and nonellipsoidal light curves: Challenges from mass determinations in x-ray binary stars

    Science.gov (United States)

    Cantrell, Andrew Glenn

    We consider two types of anomalous observations which have arisen from efforts to measure dynamical masses of X-ray binary stars: (1) Radial velocity curves which seemingly show the primary and the secondary out of antiphase in most systems, and (2) The observation of double-waved light curves which deviate significantly from the ellipsoidal modulations expected for a Roche lobe filling star. We consider both problems with the joint goals of understanding the physical origins of the anomalous observations, and using this understanding to allow robust dynamical determinations of mass in X-ray binary systems. In our analysis of phase-shifted radial velocity curves, we discuss a comprehensive sample of X-ray binaries with published phase-shifted radial velocity curves. We show that the most commonly adopted explanation for phase shifts is contradicted by many observations, and consider instead a generalized form of a model proposed by Smak in 1970. We show that this model is well supported by a range of observations, including some systems which had previously been considered anomalous. We lay the groundwork for the derivation of mass ratios based on our explanation for phase shifts, and we discuss the work necessary to produce more detailed physical models of the phase shift. In our analysis of non-ellipsoidal light curves, we focus on the very well-studied system A0620-00. We present new VIH SMARTS photometry spanning 1999-2007, and supplement this with a comprehensive collection of archival data obtained since 1981. We show that A0620-00 undergoes optical state changes within X-ray quiescence and argue that not all quiescent data should be used for determinations of the inclination. We identify twelve light curves which may reliably be used for determining the inclination. We show that the accretion disk contributes significantly to all twelve curves and is the dominant source of nonellipsoidal variations. We derive the disk fraction for each of the twelve curves

  14. Empiric potassium supplementation and increased survival in users of loop diuretics.

    Directory of Open Access Journals (Sweden)

    Charles E Leonard

    Full Text Available The effectiveness of the clinical strategy of empiric potassium supplementation in reducing the frequency of adverse clinical outcomes in patients receiving loop diuretics is unknown. We sought to examine the association between empiric potassium supplementation and 1 all-cause death and 2 outpatient-originating sudden cardiac death (SD and ventricular arrhythmia (VA among new starters of loop diuretics, stratified on initial loop diuretic dose.We conducted a one-to-one propensity score-matched cohort study using 1999-2007 US Medicaid claims from five states. Empiric potassium supplementation was defined as a potassium prescription on the day of or the day after the initial loop diuretic prescription. Death, the primary outcome, was ascertained from the Social Security Administration Death Master File; SD/VA, the secondary outcome, from incident, first-listed emergency department or principal inpatient SD/VA discharge diagnoses (positive predictive value = 85%.We identified 654,060 persons who met eligibility criteria and initiated therapy with a loop diuretic, 27% of whom received empiric potassium supplementation (N = 179,436 and 73% of whom did not (N = 474,624. The matched hazard ratio for empiric potassium supplementation was 0.93 (95% confidence interval, 0.89-0.98, p = 0.003 for all-cause death. Stratifying on initial furosemide dose, hazard ratios for empiric potassium supplementation with furosemide < 40 and ≥ 40 milligrams/day were 0.93 (0.86-1.00, p = 0.050 and 0.84 (0.79-0.89, p < 0.0001. The matched hazard ratio for empiric potassium supplementation was 1.02 (0.83-1.24, p = 0.879 for SD/VA.Empiric potassium supplementation upon initiation of a loop diuretic appears to be associated with improved survival, with a greater apparent benefit seen with higher diuretic dose. If confirmed, these findings support the use of empiric potassium supplementation upon initiation of a loop diuretic.

  15. Characterising fifteen years of continuous atmospheric radon activity observations at Cape Point (South Africa)

    Science.gov (United States)

    Botha, R.; Labuschagne, C.; Williams, A. G.; Bosman, G.; Brunke, E.-G.; Rossouw, A.; Lindsay, R.

    2018-03-01

    winter and spring seasons is found over the 15-year data set, with most of the change occurring in the first 9 years (1999-2007). This observed inter-annual decline appears to be associated with changes in the frequency of air masses having originated from over the African continental surfaces, and no significant trend is found in the lower radon percentiles associated with oceanic air masses. The general decrease of atmospheric radon-associated with continental air-masses at Cape Point could be attributed to changing meteorological conditions, possibly driven by climate change.

  16. Mass changes of Southern and Northern Inylchek Glacier, Central Tian Shan, Kyrgyzstan, during ∼1975 and 2007 derived from remote sensing data

    Science.gov (United States)

    Shangguan, D. H.; Bolch, T.; Ding, Y. J.; Kröhnert, M.; Pieczonka, T.; Wetzel, H. U.; Liu, S. Y.

    2015-04-01

    Glacier melt is an essential source of freshwater for the arid regions surrounding the Tian Shan. However, the knowledge about glacier volume and mass changes over the last decades is limited. In the present study, glacier area, glacier dynamics and mass changes are investigated for the period ~1975-2007 for Southern Inylchek Glacier (SIG) and Northern Inylchek Glacier (NIG), the largest glacier system in Central Tian Shan separated by the regularly draining Lake Merzbacher. The area of NIG increased by 2.0 ± 0.1 km2 (~1.3%) in the period ~1975-2007. In contrast, SIG has shrunk continuously in all investigated periods since ~1975. Velocities of SIG in the central part of the ablation region reached ~100-120 m a-1 in 2002/2003, which was slightly higher than the average velocity in 2010/2011. The central part of SIG flows mainly towards Lake Merzbacher rather than towards its terminus. The measured velocities at the distal part of the terminus downstream of Lake Merzbacher were below the uncertainty, indicating very low flow with even stagnant parts. Geodetic glacier mass balances have been calculated using multi-temporal digital elevation models from KH-9 Hexagon (representing the year 1975), SRTM3 (1999), ALOS PRISM (2006) and SPOT-5 high-resolution geometrical (HRG) data (2007). In general, a continuous mass loss for both SIG and NIG could be observed between ~1975 and 2007. SIG lost mass at a rate of 0.43 ± 0.10 m w.e. a-1 and NIG at a rate of 0.25 ± 0.10 m w.e. a-1 within the period ~1975-1999. For the period 1999-2007, the highest mass loss of 0.57 ± 0.46 m w.e. a-1 was found for NIG, whilst SIG showed a potential moderate mass loss of 0.28 ± 0.46 m w.e. a-1. Both glaciers showed a small retreat during this period. Between ~1975 and 1999, we identified a thickening at the front of NIG with a maximum surface elevation increase of about 150 m as a consequence of a surge event. In contrast significant thinning (>0.5 m a-1) and comparatively high velocities

  17. The value of level III clearance in patients with axillary and sentinel node positive breast cancer.

    LENUS (Irish Health Repository)

    Dillon, Mary F

    2012-02-01

    BACKGROUND: The value of level III axillary clearance is contentious, with great variance worldwide in the extent and levels of clearance performed. OBJECTIVE: To determine rates of level III positivity in patients undergoing level I-III axillary clearance, and identify which patients are at highest risk of involved level III nodes. METHODS: From a database of 2850 patients derived from symptomatic and population-based screening service, 1179 patients who underwent level I-III clearance between the years 1999-2007 were identified. The pathology, surgical details, and prior sentinel nodes biopsies of patients were recorded. RESULTS: Eleven hundred seventy nine patients had level I-III axillary clearance. Of the patients, 63% (n = 747) were node positive. Of patients with node positive disease, 23% (n = 168) were level II positive and 19% (n = 141) were level III positive. Two hundred fifty patients had positive sentinel node biopsies prior to axillary clearance. Of these, 12% (n = 30) and 9% (n = 22) were level II and level III positive, respectively. On multivariate analysis, factors predictive of level III involvement in patients with node positive disease were tumor size (P < 0.001, OR = 1.36; 95% CI: 1.2-1.5), invasive lobular disease (P < 0.001, OR = 3.6; 95% CI: 1.9-6.95), extranodal extension (P < 0.001, OR = 0.27; 95% CI: 0.18-0.4), and lymphovascular invasion (P = 0.04, OR = 0.58; 95% CI: 0.35-1). Lobular invasive disease (P = 0.049, OR = 4.1; 95% CI: 1-16.8), extranodal spread (P = 0.003, OR = 0.18; 95% CI: 0.06-0.57), and having more than one positive sentinel node (P = 0.009, OR = 4.9; 95% CI: 1.5-16.1) were predictive of level III involvement in patients with sentinel node positive disease. CONCLUSION: Level III clearance has a selective but definite role to play in patients who have node positive breast carcinoma. Pathological characteristics of the primary tumor are of particular use in identifying those who are at various risk of level III nodal

  18. Cytogenetical and haematological studies of hydrobionts within the Chernobyl accident exclusion zone

    International Nuclear Information System (INIS)

    Gudkov, Dmitri; Dzyubenko, Elena; Shevtsova, Natalia; Nurgudin, Marat

    2008-01-01

    Full text: We studied the cytogenetic effects in embryo tissue of gastropod snails and in root meristem of higher aquatic plants as chromosome aberration rate and reaction of snails on unfavorable condition of environment as change of structure, level of differentiation, death and cytogenetic stability of hemo lymph cell population. Our researches were carried out during 1999-2007. The water bodies of research were Azbuchin Lake, Yanovsky Crawl, Dalekoye Lake, Glubokoye Lake as well as Uzh River and Pripyat River within the Chernobyl accident exclusion zone. The results of the analyses compared to the data received for hydrobionts from control lakes, located within the Kiev City area. The absorbed dose rate registered in range from 1.3 mGy/year to 3.4 Gy/year. The highest rate was found in Dalekoye and Glubokoye lakes, the lowest - in the Pripyat River and Uzh River. Hydrobionts from the control lakes were characterized by absorbed dose rate about 0.3 mGy/year The rate of chromosome aberration for snails from the control lakes was about 1.1-2.0 percent. About 3.3 and 5.7 % of aberrant cells was registered in snail's embryo from the Pripyat and Uzh rivers respectively. The highest rate of aberration was found in snails from lakes within the dammed territory on the left-bank flood lands of the Pripyat River (Dalekoye-1 Lake and Glubokoye Lake) - 21-23 %. In the embryo tissue of snails from Yanovsky Crawl chromosome aberration rate was about 18 % and in Azbuchin Lake - about 20 %. The highest chromosome aberrations rate in root meristems (17.8-10.8 %) were registered in plants from lakes within the left-bank flood lands of the Pripyat River, the lowest one (4.5-2.2 %) - in plants from the Pripyat and Uzh rivers. In hemo lymph of snails from Dalekoye-1 Lake, Azbuchin Lake and Glubokoye Lake the quantity of death cells averages 36.2 %, 39.2 % and 43.8 % respectively, the part of phagocytic cells averages 44.3 %, 41.2 % and 45.0 %, as well as decrease of the young

  19. A population-based analysis of mortality in patients with Turner syndrome and hypoplastic left heart syndrome using the Texas Birth Defects Registry.

    Science.gov (United States)

    Lara, Diego A; Ethen, Mary K; Canfield, Mark A; Nembhard, Wendy N; Morris, Shaine A

    2017-01-01

    Hypoplastic left heart syndrome (HLHS) is strongly associated with Turner syndrome (TS); outcome data when these conditions coexist is sparse. We aimed to investigate long-term survival and causes of death in this population. The Texas Birth Defects Registry was queried for all live born infants with HLHS during 1999-2007. We used Kaplan-Meier and Cox regression analyses to compare survival among patients with HLHS with TS (HLHS/TS+) to patients who had HLHS without genetic disorders or extracardiac birth defects (HLHS/TS-). Of the 542 patients with HLHS, 11 had TS (2.0%), 71 had other extracardiac birth defects or genetic disorders, and 463 had neither. The median follow-up time was 4.2 y (interquartile range [IQR] 2.1-6.5). Comparing those with HLHS/TS+ to HLHS/TS-, 100% versus 35% were female (P < .001), and median birth weight was 2140 g (IQR 1809-2650) versus 3196 g (IQR 2807-3540, P < .001). Neonatal mortality was 36% in HLHS/TS+ versus 27% in HLHS/TS- (log rank = 0.431). Ten of the 11 TS+ patients died during the study period for cumulative mortality of 91% versus 50% (hazard ratio (HR) for TS+: 2.90, 95% CI 1.53-5.48). Six patients died prior to surgery, 5 underwent Stage 1 palliation (S1P), 3 died after S1P, 2 survived past S2P, and one of these died at age 19 mo. The underlying cause of death was listed as congenital heart disease on all the death certificates of HLHS/TS+ patients. In multivariable analysis controlling for low birth weight (<2500 g), TS remained associated with significantly increased cumulative mortality, although females without TS had higher mortality than males (HR for TS+ versus males: 2.42, 95% CI 1.24-4.73; HR for TS- females versus males: 1.41, 95% CI 1.08-1.83). TS with HLHS is associated with significant mortality. The increased mortality in females without documented TS calls to question if TS is undetected in a portion of females with HLHS. © 2016 Wiley Periodicals, Inc.

  20. Spontaneous Resolution of Vesicoureteral Reflux (VUR in Iranian Children, a Single Center Experience in 533 Cases

    Directory of Open Access Journals (Sweden)

    M Sharifian

    2012-05-01

    Full Text Available

    Background and Objectives

    Experience with vesicoureteral reflux (VUR differs in different centers and there are lots of controversies surrounding this issue. The aim of this study was to evaluate Spontaneous resolution and prognosis of the disease among Iranian children.

     

    Methods

    In this case series study, 1278 children with urinary tract infection and visited at pediatric nephrology clinic in Tehran, Iran during 1999-2007 were studied. Primary VUR was found in 533 Patients. Following the diagnosis, the patients received prophylactic antibiotic and were annually followed with radionucleo cystography (RNC. Patients underwent surgery in case the medical treatment failed (breakthrough infection or new renal scar formation.

     

    Results

    533 patients with VUR were studied. Patients’ mean age with VUR was 3.7±2.4 years (range: 2 days to 18 years old. During an average follow-up duration of 3.3+2.2 years, spontaneous resolution was observed in 40% of 279 patients who had follow-up RNCs. The mean interval between VUR diagnosis and spontaneous resolution was 1.5+ 1 years (range: 2 months to 6 years. The resolution rate was decreased with increment of reflux grade so that for grades I to V, VUR was resolved in 63%, 57%, 27%, 22% and 10% of the cases, respectively. Anti reflux surgery was performed in 27(10% of patients during follow-up.

     

    Conclusion

    Based on the excellent results obtained from clinical therapy using low dose antibiotics, it is recommended that VUR grades 1 to 4 be managed medically with low-dose oral antibiotic prophylaxis and close follow-ups.

  1. Incidents in transport of radioactive materials for civil use: IRSN draws lessons from events reported between 1999 and 2007

    International Nuclear Information System (INIS)

    2008-01-01

    analysis illustrates the annual change in the number of events in transport of radioactive materials, with the associated levels of seriousness. It also provides a brief description of some of the events (those with radiological aspect and the main events occurred in 2007 and an analysis of the most frequent types of events over the period 1999-2007, giving the observed trends. Finally, the main elements that could be deduced from this feedback are presented. This report could be useful for ASN in order to improve safety of radioactive material transports. (authors)

  2. RECONCEPTUALIZING CONSENT FOR DIRECT-TO-CONSUMER HEALTH SERVICES.

    Science.gov (United States)

    Spector-Bagdady, Kayte

    2015-01-01

    The market for direct-to-consumer (DTC) health services continues to grow rapidly with former patients converting to customers for the opportunity to purchase varied diagnostic tests without the involvement of their clinician. For the first time a DTC genetic testing company is advertising health-related reports "that meet [Food and Drug Administration] standards for being clinically and scientifically valid." Ethicists and regulatory agencies alike have recognized the need for a more informed transaction in the DTC context, but how should we classify a commercial transaction for something normally protected by a duty of care? How can we assure informed agreements in an industry with terms and conditions as varied as the services performed? The doctrine of "informed consent" began as an ethical construct building on the promise of beneficence in the clinical relationship and elevating the principle of autonomy--but in the DTC context should we hold providers to legal standards of informed consent and associated medical malpractice liability, or contractual obligations where consumers would seek remedy for breach? This Article analyzes the fine balance that must be struck in an industry where companies are selling services for entertainment or non-medical purposes that possess the capacity to produce serious and disquieting medical information. It begins by reviewing current standards of consent in the clinical setting from both a legal and ethical perspective and then lays forth current standards for DTC consent using two currently controversial case studies: that of keepsake fetal ultrasound and genetic testing. DTC keepsake ultrasound and genetic testing providers attempt to de-medicalize the devices used for these procedures from their intended medical uses to non-medical uses. But while keepsake ultrasound is marketed as "intended for entertainment purposes only," it can provide medical information as an incidental finding. 23andMe currently purports to be the

  3. Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

    Science.gov (United States)

    Schormair, Barbara; Zhao, Chen; Bell, Steven; Tilch, Erik; Salminen, Aaro V; Pütz, Benno; Dauvilliers, Yves; Stefani, Ambra; Högl, Birgit; Poewe, Werner; Kemlink, David; Sonka, Karel; Bachmann, Cornelius G; Paulus, Walter; Trenkwalder, Claudia; Oertel, Wolfgang H; Hornyak, Magdolna; Teder-Laving, Maris; Metspalu, Andres; Hadjigeorgiou, Georgios M; Polo, Olli; Fietze, Ingo; Ross, Owen A; Wszolek, Zbigniew; Butterworth, Adam S; Soranzo, Nicole; Ouwehand, Willem H; Roberts, David J; Danesh, John; Allen, Richard P; Earley, Christopher J; Ondo, William G; Xiong, Lan; Montplaisir, Jacques; Gan-Or, Ziv; Perola, Markus; Vodicka, Pavel; Dina, Christian; Franke, Andre; Tittmann, Lukas; Stewart, Alexandre F R; Shah, Svati H; Gieger, Christian; Peters, Annette; Rouleau, Guy A; Berger, Klaus; Oexle, Konrad; Di Angelantonio, Emanuele; Hinds, David A; Müller-Myhsok, Bertram; Winkelmann, Juliane

    2017-11-01

    Restless legs syndrome is a prevalent chronic neurological disorder with potentially severe mental and physical health consequences. Clearer understanding of the underlying pathophysiology is needed to improve treatment options. We did a meta-analysis of genome-wide association studies (GWASs) to identify potential molecular targets. In the discovery stage, we combined three GWAS datasets (EU-RLS GENE, INTERVAL, and 23andMe) with diagnosis data collected from 2003 to 2017, in face-to-face interviews or via questionnaires, and involving 15 126 cases and 95 725 controls of European ancestry. We identified common variants by fixed-effect inverse-variance meta-analysis. Significant genome-wide signals (p≤5 × 10 -8 ) were tested for replication in an independent GWAS of 30 770 cases and 286 913 controls, followed by a joint analysis of the discovery and replication stages. We did gene annotation, pathway, and gene-set-enrichment analyses and studied the genetic correlations between restless legs syndrome and traits of interest. We identified and replicated 13 new risk loci for restless legs syndrome and confirmed the previously identified six risk loci. MEIS1 was confirmed as the strongest genetic risk factor for restless legs syndrome (odds ratio 1·92, 95% CI 1·85-1·99). Gene prioritisation, enrichment, and genetic correlation analyses showed that identified pathways were related to neurodevelopment and highlighted genes linked to axon guidance (associated with SEMA6D), synapse formation (NTNG1), and neuronal specification (HOXB cluster family and MYT1). Identification of new candidate genes and associated pathways will inform future functional research. Advances in understanding of the molecular mechanisms that underlie restless legs syndrome could lead to new treatment options. We focused on common variants; thus, additional studies are needed to dissect the roles of rare and structural variations. Deutsche Forschungsgemeinschaft, Helmholtz Zentrum

  4. Mica-feldspar equilibria in supercritical alkali chloride solutions

    Science.gov (United States)

    Gunter, W. D.; Eugster, H. P.

    1981-09-01

    The equilibrium position of the reaction 410_2005_Article_BF01166763_TeX2GIFE1.gif begin{gathered} 1.5 KAlSi_3 O_8 + HCl = 0.5 KAl_3 Si_3 O_{10} (OH)_2 \\ + 3SiO_2 + KCl \\ has been located at 1 and 2 kb pressure and temperatures between 600° and 670° C using the Ag-AgCl buffer. These data can be combined with information on the dissociation of KC1, HC1 and H2O to determine species abundances in supercritical aqueous fluids in equilibrium with muscovite — K-feldspar — quartz assemblages. Chloride species become increasingly associated with increasing T, increasing total molality, ( m tot orm_{Cl_{tot} } ), and decreasingP_{H_2 O} . Master variable diagrams indicate that the pH of the solutions may vary from near neutral to quite acid. Published data on the paragonite-albite-quartz reaction and exchange reactions involving feldspars and micas were included to calculate speciation in mica-feldspar-NaCl-KCl-HCl-H2O fluids at 2kb pressure and temperatures between 300° and 600° C. The data are not accurate enough to distinguish different feldspar structural states. Concentration gradients were calculated for individual species between K-feldspar+quartz, muscovite+quartz and andalusite+quartz assemblages at 500° C, 2 kb. Assuming that the proton diffuses most rapidly and that there are no [H+] gradients, the molality of the solution must vary 30-fold, with feldspar+quartz at the more concentrated side. The data on mica-feldspar-chloride equilibria are used to interpret the spacial distribution of micas, feldspar and quartz in microfolds. This distribution can be accounted for by pressure solution, due to the fact that non-hydrostatic pressure affects congruently dissolving minerals, auch as quartz, differently from minerals which dissolve incongruently, such as micas and feldspars. We postulate, that during folding at constantP_{H_2 O} , T andm_{Cl - } , gradients in KC1 and SiO2 are created by stress differences between hinge and limb of a microfold, such that

  5. Transitioning pharmacogenomics into the clinical setting: training future pharmacists

    Directory of Open Access Journals (Sweden)

    Amber Frick

    2016-08-01

    Full Text Available Pharmacogenomics, once hailed as a futuristic approach to pharmacotherapy, has transitioned to clinical implementation. Although logistic and economic limitations to clinical pharmacogenomics are being superseded by external measures such as preemptive genotyping, implementation by clinicians has met resistance, partly due to a lack of education. Pharmacists, with extensive training in pharmacology and pharmacotherapy and accessibility to patients, are ideally suited to champion clinical pharmacogenomics. This study aimed to analyze the outcomes of an innovative pharmacogenomic teaching approach.Second-year student pharmacists enrolled in a required, 15-week pharmaceutical care lab course in 2015 completed educational activities including lectures and small group work focusing on practical pharmacogenomics. Reflecting the current landscape of direct-to-consumer genomic testing, students were offered 23andMe genotyping. Students completed surveys regarding their attitudes and confidence on pharmacogenomics prior to and following the educational intervention. Paired pre- and post-intervention responses were analyzed with McNemar’s test for binary comparisons and the Wilcoxon signed-rank test for Likert items. Responses between genotyped and non-genotyped students were analyzed with Fisher’s exact test for binary comparisons and the Mann-Whitney U-test for Likert items.Responses were analyzed for all student pharmacists who voluntarily completed the pre-intervention survey (N=121, 83% response and for student pharmacists who completed both pre- and post-intervention surveys (N=39, 27% response. Of those who completed both pre- and post-intervention surveys, 59% obtained genotyping. Student pharmacists demonstrated a significant increase in their knowledge of pharmacogenomic resources (17.9% vs. 56.4%, p<0.0001 and confidence in applying pharmacogenomic information to manage patients’ drug therapy (28.2% vs. 48.7%, p=0.01, particularly if the

  6. Social Media: A Review and Tutorial of Applications in Medicine and Health Care

    Science.gov (United States)

    Sheps, Samuel; Ho, Kendall; Novak-Lauscher, Helen; Eysenbach, Gunther

    2014-01-01

    Background Social media are dynamic and interactive computer-mediated communication tools that have high penetration rates in the general population in high-income and middle-income countries. However, in medicine and health care, a large number of stakeholders (eg, clinicians, administrators, professional colleges, academic institutions, ministries of health, among others) are unaware of social media’s relevance, potential applications in their day-to-day activities, as well as the inherent risks and how these may be attenuated and mitigated. Objective We conducted a narrative review with the aim to present case studies that illustrate how, where, and why social media are being used in the medical and health care sectors. Methods Using a critical-interpretivist framework, we used qualitative methods to synthesize the impact and illustrate, explain, and provide contextual knowledge of the applications and potential implementations of social media in medicine and health care. Both traditional (eg, peer-reviewed) and nontraditional (eg, policies, case studies, and social media content) sources were used, in addition to an environmental scan (using Google and Bing Web searches) of resources. Results We reviewed, evaluated, and synthesized 76 articles, 44 websites, and 11 policies/reports. Results and case studies are presented according to 10 different categories of social media: (1) blogs (eg, WordPress), (2) microblogs (eg, Twitter), (3) social networking sites (eg, Facebook), (4) professional networking sites (eg, LinkedIn, Sermo), (5) thematic networking sites (eg, 23andMe), (6) wikis (eg, Wikipedia), (7) mashups (eg, HealthMap), (8) collaborative filtering sites (eg, Digg), (9) media sharing sites (eg, YouTube, Slideshare), and others (eg, SecondLife). Four recommendations are provided and explained for stakeholders wishing to engage with social media while attenuating risk: (1) maintain professionalism at all times, (2) be authentic, have fun, and do not be

  7. Social media: a review and tutorial of applications in medicine and health care.

    Science.gov (United States)

    Grajales, Francisco Jose; Sheps, Samuel; Ho, Kendall; Novak-Lauscher, Helen; Eysenbach, Gunther

    2014-02-11

    Social media are dynamic and interactive computer-mediated communication tools that have high penetration rates in the general population in high-income and middle-income countries. However, in medicine and health care, a large number of stakeholders (eg, clinicians, administrators, professional colleges, academic institutions, ministries of health, among others) are unaware of social media's relevance, potential applications in their day-to-day activities, as well as the inherent risks and how these may be attenuated and mitigated. We conducted a narrative review with the aim to present case studies that illustrate how, where, and why social media are being used in the medical and health care sectors. Using a critical-interpretivist framework, we used qualitative methods to synthesize the impact and illustrate, explain, and provide contextual knowledge of the applications and potential implementations of social media in medicine and health care. Both traditional (eg, peer-reviewed) and nontraditional (eg, policies, case studies, and social media content) sources were used, in addition to an environmental scan (using Google and Bing Web searches) of resources. We reviewed, evaluated, and synthesized 76 articles, 44 websites, and 11 policies/reports. Results and case studies are presented according to 10 different categories of social media: (1) blogs (eg, WordPress), (2) microblogs (eg, Twitter), (3) social networking sites (eg, Facebook), (4) professional networking sites (eg, LinkedIn, Sermo), (5) thematic networking sites (eg, 23andMe), (6) wikis (eg, Wikipedia), (7) mashups (eg, HealthMap), (8) collaborative filtering sites (eg, Digg), (9) media sharing sites (eg, YouTube, Slideshare), and others (eg, SecondLife). Four recommendations are provided and explained for stakeholders wishing to engage with social media while attenuating risk: (1) maintain professionalism at all times, (2) be authentic, have fun, and do not be afraid, (3) ask for help, and (4) focus

  8. Diet and exercise changes following direct-to-consumer personal genomic testing.

    Science.gov (United States)

    Nielsen, Daiva Elena; Carere, Deanna Alexis; Wang, Catharine; Roberts, J Scott; Green, Robert C

    2017-05-02

    The impacts of direct-to-consumer personal genomic testing (PGT) on health behaviors such as diet and exercise are poorly understood. Our investigation aimed to evaluate diet and exercise changes following PGT and to determine if changes were associated with genetic test results obtained from PGT. Customers of 23andMe and Pathway Genomics completed a web-based survey prior to receiving PGT results (baseline) and 6 months post-results. Fruit and vegetable intake (servings/day), and light, vigorous and strength exercise frequency (days/week) were assessed. Changes in diet and exercise were examined using paired t-tests and linear regressions. Additional analyses examined whether outcomes differed by baseline self-reported health (SRH) or content of PGT results. Longitudinal data were available for 1,002 participants. Significant increases were observed for vegetable intake (mean Δ = 0.11 (95% CI = 0.05, 0.17), p = 0.0003) and strength exercise (Δ = 0.14 (0.03, 0.25), p = 0.0153). When stratified by SRH, significant increases were observed for all outcomes among lower SRH participants: fruit intake, Δ = 0.11 (0.02, 0.21), p = 0.0148; vegetable intake, Δ = 0.16 (0.07, 0.25), p = 0.0005; light exercise, Δ = 0.25 (0.03, 0.47), p = 0.0263; vigorous exercise, Δ = 0.23 (0.06, 0.41), p = 0.0097; strength exercise, Δ = 0.19 (0.01, 0.37), p = 0.0369. A significant change among higher SRH participants was only observed for light exercise, and in the opposite direction: Δ = -0.2468 (-0.06, -0.44), p = 0.0111. Genetic results were not consistently associated with any diet or exercise changes. The experience of PGT was associated with modest, mostly positive changes in diet and exercise. Associations were independent of genetic results from PGT.

  9. PREFACE: International Workshop on Neutron Optics and Detectors (NOP&D 2013)

    Science.gov (United States)

    2014-07-01

    Every two-three years scientists involved in developments of neutron optics gather together for the International Workshop on Neutron Optics (NOP). Neutron optics has always been considered very important for the development of new neutron instrumentation. The limited brilliance of existing or future neutron sources requires the more effective usage of emitted neutrons. Indeed, improvements of the neutron optical system or an optimization of the neutron-optical tracts of instruments can result in a significant enhancement of their performance. This is especially important at present when the neutron scattering community is strongly engaged in developments of new instrumentation around the spallation neutron sources - SNS, ESS, J-PARC and Second Target Station at ISIS. In 2013 the workshop was organized by the Jülich Centre for Neutron Science of the Forschungszentrum Jülich GmbH and was held at the Conference Centre in Ismaning next to Munich on July 2-7, 2013 on the eve of the ICNS-2013 in Edinburg. It carried on the series of Neutron Optics workshops held in Villigen (1999, 2007), Tokyo (2004) and Alpe d'Huez (2010). This time it is also aimed to compliment the International Conference on Neutron Scattering in Edinburgh (ICNS-2013) by providing a platform for detailed discussions on the latest developments in the field of neutron optics. The scope of the workshop was extended to the neutron detectors (in a way similar to the NOP-2004 held in Tokyo) and was labelled as the International Workshop on Neutron Optics and Detectors, NOP&D-2013. However, in contrast to the Tokyo workshop, the focus of discussions was not the detector technologies (which are the subject of many dedicated meetings), rather than the use of detectors for the purpose of the design of modern instrumentation aiming to inform detector developers about real detectors requirements for new advanced instrumental concepts. The three-full-days workshop gathered a record number of participants, more

  10. Comparison of the HadGEM2 climate-chemistry model against in-situ and SCIAMACHY atmospheric methane data

    Science.gov (United States)

    Hayman, G. D.; O'Connor, F. M.; Dalvi, M.; Clark, D. B.; Gedney, N.; Huntingford, C.; Prigent, C.; Buchwitz, M.; Schneising, O.; Burrows, J. P.; Wilson, C.; Richards, N.; Chipperfield, M.

    2014-05-01

    Wetlands are a major emission source of methane (CH4) globally. In this study, we have evaluated wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator) against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates were investigated: (a) from an offline run driven with CRU-NCEP meteorological data and (b) from the same offline run in which the modelled wetland fractions were replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS) remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999-2007) is in line with other recently-published estimates. There are regional differences as the unconstrained JULES inventory gave significantly higher emissions in the Amazon and lower emissions in other regions compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2), we have evaluated these JULES wetland emissions against atmospheric observations of methane. We obtained improved agreement with the surface concentration measurements, especially at northern high latitudes, compared to previous HadGEM2 runs using the wetland emission dataset of Fung (1991). Although the modelled monthly atmospheric methane columns reproduced the large-scale patterns in the SCIAMACHY observations, they were biased low by 50 part per billion by volume (ppb). Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE-ACE assimilated TOMCAT output resulted in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain JULES-derived wetland fraction improved the description of the wetland emissions in JULES and gave a good description of the seasonality

  11. Comparison of the HadGEM2 climate-chemistry model against in situ and SCIAMACHY atmospheric methane data

    Science.gov (United States)

    Hayman, G. D.; O'Connor, F. M.; Dalvi, M.; Clark, D. B.; Gedney, N.; Huntingford, C.; Prigent, C.; Buchwitz, M.; Schneising, O.; Burrows, J. P.; Wilson, C.; Richards, N.; Chipperfield, M.

    2014-12-01

    Wetlands are a major emission source of methane (CH4) globally. In this study, we evaluate wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator) against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates are investigated: (a) from an offline run driven with Climatic Research Unit-National Centers for Environmental Prediction (CRU-NCEP) meteorological data and (b) from the same offline run in which the modelled wetland fractions are replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS) remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999-2007) is in line with other recently published estimates. There are regional differences as the unconstrained JULES inventory gives significantly higher emissions in the Amazon (by ~36 Tg CH4 yr-1) and lower emissions in other regions (by up to 10 Tg CH4 yr-1) compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2), we evaluate these JULES wetland emissions against atmospheric observations of methane. We obtain improved agreement with the surface concentration measurements, especially at high northern latitudes, compared to previous HadGEM2 runs using the wetland emission data set of Fung et al. (1991). Although the modelled monthly atmospheric methane columns reproduce the large-scale patterns in the SCIAMACHY observations, they are biased low by 50 part per billion by volume (ppb). Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE-ACE assimilated TOMCAT output results in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain the JULES-derived wetland

  12. Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children.

    Science.gov (United States)

    Schaefer, Franz; Trachtman, Howard; Wühl, Elke; Kirchner, Marietta; Hayek, Salim S; Anarat, Ali; Duzova, Ali; Mir, Sevgi; Paripovic, Dusan; Yilmaz, Alev; Lugani, Francesca; Arbeiter, Klaus; Litwin, Mieczyslaw; Oh, Jun; Matteucci, Maria Chiara; Gellermann, Jutta; Wygoda, Simone; Jankauskiene, Augustina; Klaus, Günter; Dusek, Jiri; Testa, Sara; Zurowska, Aleksandra; Caldas Afonso, Alberto; Tracy, Melissa; Wei, Changli; Sever, Sanja; Smoyer, William; Reiser, Jochen

    2017-11-06

    Conventional methods to diagnose and monitor chronic kidney disease (CKD) in children, such as creatinine level and cystatin C-derived estimated glomerular filtration rate (eGFR) and assessment of proteinuria in spot or timed urine samples, are of limited value in identifying patients at risk of progressive kidney function loss. Serum soluble urokinase receptor (suPAR) levels strongly predict incident CKD stage 3 in adults. To determine whether elevated suPAR levels are associated with renal disease progression in children with CKD. Post hoc analysis of 2 prospectively followed up pediatric CKD cohorts, ie, the ESCAPE Trial (1999-2007) and the 4C Study (2010-2016), with serum suPAR level measured at enrollment and longitudinal eGFR measured prospectively. In the 2 trials, a total of 898 children were observed at 30 (ESCAPE Trial; n = 256) and 55 (4C Study; n = 642) tertiary care hospitals in 13 European countries. Renal diagnoses included congenital anomalies of the kidneys and urinary tract (n = 637 [70.9%]), tubulointerstitial nephropathies (n = 92 [10.2%]), glomerulopathies (n = 69 [7.7%]), postischemic CKD (n = 42 [4.7%]), and other CKD (n = 58 [6.5%]). Total follow-up duration was up to 7.9 years, and median follow-up was 3.1 years. Analyses were conducted from October 2016 to December 2016. Serum suPAR level was measured at enrollment, and eGFR was measured every 2 months in the ESCAPE Trial and every 6 months in the 4C Study. The primary end point of CKD progression was a composite of 50% eGFR loss, eGFR less than 10 mL/min/1.73 m2, or initiation of renal replacement therapy. The primary end point in this study was renal survival, defined as a composite of 50% loss of GFR that persisted for at least 1 month, the start of renal replacement therapy, or an eGFR less than 10 mL/min/1.73 m2. Of the 898 included children, 560 (62.4%) were male, and the mean (SD) patient age at enrollment was 11.9 (3.5) years. The mean (SD) eGFR was 34

  13. Crowdsourced health research studies: an important emerging complement to clinical trials in the public health research ecosystem.

    Science.gov (United States)

    Swan, Melanie

    2012-03-07

    conditions. PatientsLikeMe and 23andMe are the leading operators of researcher-organized, crowdsourced health research studies. These operators have published findings in the areas of disease research, drug response, user experience in crowdsourced studies, and genetic association. Quantified Self, Genomera, and DIYgenomics are communities of participant-organized health research studies where individuals conduct self-experimentation and group studies. Crowdsourced health research studies have a diversity of intended outcomes and levels of scientific rigor. Participatory health initiatives are becoming part of the public health ecosystem and their rapid growth is facilitated by Internet and social networking influences. Large-scale parameter-stratified cohorts have potential to facilitate a next-generation understanding of disease and drug response. Not only is the large size of crowdsourced cohorts an asset to medical discovery, too is the near-immediate speed at which medical findings might be tested and applied. Participatory health initiatives are expanding the scope of medicine from a traditional focus on disease cure to a personalized preventive approach. Crowdsourced health research studies are a promising complement and extension to traditional clinical trials as a model for the conduct of health research.

  14. What has happened in about the last 20 years in the Canyoles watershed?

    Science.gov (United States)

    Ángel González Peñaloza, Félix; Cerdà, Artemi; Díaz del Olmo, Fernando

    2013-04-01

    Along history, the Mediterranean arid lands have undergone widespread land use transformation, especially in recent decades (Piqueras, 2012). There are changes driven by socio-economic conditions, such as European Agricultural Policies (MacDonald et al., 2000; Keenleyside and Tucker, 2010; Renwick et al., 2013), which have caused land degradation processes (soil erosion, soil sealing, water pollution, salinization, wildfires, land abandonment, urban sprawl and intensive agricultural practices). Land degradation is the results of a complex Socio Ecological System (SES) which should be addressed using the Geographical Information System (GIS) to identify and assess the spatial variation of land use change. Therefore, the aim of this work has been to describe and assess the land use change by human activities in a typical Mediterranean watershed (Cànyoles Valley) located at South-East of Iberian Peninsula as a part of the Land Ecosystem and Degradation Desertification Response Assessment (LEDDRA) project, which has undergone a quick land use change in last two decades (1986 - 2005). Results reveal that the surface area devoted to rainfed crops (e.g., olive crops (47 %) and vineyards (28 %) and forestry have decline significantly; while the citrus orchards (irrigated crops) and unproductive areas (e.g., roads and railways, urban areas) have been increasing its surface in just about last 20 years in 45 % and 67 %, respectively. According to the literature review (Cerdà, 1994; Cerdá et al., 1999, 2007; Cerdà, 2007; Bodí et al., 2012; González-Peñaloza, 2012) these recent changes, in the study site, have caused many environmental disturbances mainly due to the lack control strategies plans of land degradation. Acknowledgements This research is being conducted by the EU project "Land Ecosystem and Degradation Desertification: Assessing the Fit of Responses" LEDDRA 243857 CONSORTIUM AGREEMENT. TR07 - VII PROGRAMA MARCO - ENERGÍA FP7-ENERGY-2007-2-TREN. - European

  15. Independent Technical Review of the X-740 Groundwater Remedy, Portsmouth, Ohio: Technical Evaluation and Recommendations

    International Nuclear Information System (INIS)

    Looney, B.; Rhia, B.; Jackson, D.; Eddy-Dilek, C.

    2010-01-01

    Two major remedial campaigns have been applied to a plume of trichloroethene (TCE) contaminated groundwater near the former X-740 facility at the Portsmouth Gaseous Diffusion Plant in Piketon Ohio. The two selected technologies, phytoremediation using a stand of hybrid poplar trees from 1999-2007 and in situ chemical oxidation using modified Fenton's Reagent from 2008-2009, have proven ineffective in achieving remedial action objectives (RAOs). The 'poor' performance of these technologies is a direct result of site specific conditions and the local contaminant hydrogeology. Key among these challenges is the highly heterogeneous subsurface geology with a thin contaminated aquifer zone (the Gallia) - the behavior of the contamination in the Gallia is currently dominated by slow release of TCE from the clay of the overlying Minford formation, from the sandstone of the underlying Berea formation, and from clayey layers within the Gallia itself. In response to the remediation challenges for the X-740 plume, the Portsmouth team (including the US Department of Energy (DOE), the site contractor (CDM), and the Ohio Environmental Protection Agency (OEPA)) is evaluating the feasibility of remediation at this site and identifying specific alternatives that are well matched to site conditions and that would maximize the potential for achieving RAOs. To support this evaluation, the DOE Office of Groundwater and Soil Remediation (EM-32) assembled a team of experts to serve as a resource and provide input and recommendations to Portsmouth. Despite the challenging site conditions and the failure of the previous two remediation campaigns to adequately move the site toward RAOs, the review team was unanimous in the conclusion that an effective combination of cost effective technologies can be identified. Further, the team expressed optimism that RAOs can be achieved if realistic timeframes are accepted by all parties. The initial efforts of the review team focused on reviewing the

  16. Independent Technical Review of the X-740 Groundwater Remedy, Portsmouth, Ohio: Technical Evaluation and Recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Looney, B.; Rhia, B.; Jackson, D.; Eddy-Dilek, C.

    2010-04-30

    Two major remedial campaigns have been applied to a plume of trichloroethene (TCE) contaminated groundwater near the former X-740 facility at the Portsmouth Gaseous Diffusion Plant in Piketon Ohio. The two selected technologies, phytoremediation using a stand of hybrid poplar trees from 1999-2007 and in situ chemical oxidation using modified Fenton's Reagent from 2008-2009, have proven ineffective in achieving remedial action objectives (RAOs). The 'poor' performance of these technologies is a direct result of site specific conditions and the local contaminant hydrogeology. Key among these challenges is the highly heterogeneous subsurface geology with a thin contaminated aquifer zone (the Gallia) - the behavior of the contamination in the Gallia is currently dominated by slow release of TCE from the clay of the overlying Minford formation, from the sandstone of the underlying Berea formation, and from clayey layers within the Gallia itself. In response to the remediation challenges for the X-740 plume, the Portsmouth team (including the US Department of Energy (DOE), the site contractor (CDM), and the Ohio Environmental Protection Agency (OEPA)) is evaluating the feasibility of remediation at this site and identifying specific alternatives that are well matched to site conditions and that would maximize the potential for achieving RAOs. To support this evaluation, the DOE Office of Groundwater and Soil Remediation (EM-32) assembled a team of experts to serve as a resource and provide input and recommendations to Portsmouth. Despite the challenging site conditions and the failure of the previous two remediation campaigns to adequately move the site toward RAOs, the review team was unanimous in the conclusion that an effective combination of cost effective technologies can be identified. Further, the team expressed optimism that RAOs can be achieved if realistic timeframes are accepted by all parties. The initial efforts of the review team focused on

  17. Grande Ronde Endemic Spring Chinook Salmon Supplementation Project; Lostine River Operations and Maintenance 2007 Smolt Acclimation and Adult Return Report.

    Energy Technology Data Exchange (ETDEWEB)

    Zollman, Richard L.; Eschler, Russell; Sealey, Shawn [Nez Perce Tribe

    2009-03-31

    The Nez Perce Tribe (NPT), through funding provided by the Bonneville Power Administration (BPA), has implemented a Chinook salmon supplementation program (250,000 smolts) on the Lostine River, a tributary to the Grande Ronde River of Oregon. The Grande Ronde Endemic Spring Chinook Salmon Supplementation project, which involves supplementation of the Upper Grande Ronde River and Catherine Creek in addition to the Lostine River, was established to prevent extirpation and increase the number of threatened Snake River spring/summer Chinook salmon (Oncorhynchus tshawytscha) returning to the Grande Ronde River. This report covers the eleventh season (1997-2007) of adult Chinook salmon broodstock collection in the Lostine River and the ninth season (1999-2007) of acclimation of resulting Lostine River progeny. Production of Lostine River spring Chinook salmon smolts currently occurs at Lookingglass Fish Hatchery (LGH). The Lostine River supplementation program utilizes two strategies to obtain egg source for production of smolts for supplementation: captive broodstock and conventional broodstock. The captive broodstock strategy involves (1) capture of natural juvenile spring Chinook salmon smolts from the Lostine River, (2) rearing those to adult and spawning them, and (3) rearing the resultant progeny for eventual acclimation and release back into the Lostine River. The conventional broodstock strategy involves (1) capture of natural and hatchery origin adults returning to the Lostine River, (2) holding those adults and spawning them, and (3) rearing the resultant progeny for acclimation and release back into the Lostine River. This report focuses on (1) the trapping and collection of adult spring Chinook salmon that return to the Lostine River, which provides the broodstock source for the conventional strategy and (2) the acclimation and release of juvenile spring Chinook salmon produced from the captive broodstock and conventional broodstock strategies In 2007

  18. Translation and Creative Writing: An Interview with Professor Margaret Rogers

    Directory of Open Access Journals (Sweden)

    Ruzbeh Babaee

    2016-01-01

    translator’s agency is redundant. Even texts which have standard equivalents in the other language / culture, e.g. notices such as ‘Beware of the dog’ (French Attention, chien méchant; German Vorsicht, bissiger Hund; Italian Attenti al cane!, could be translated differently if the purpose of the translation is to inform about the structure of the source text rather than produce a notice which is functionally appropriate. The scope for variation in literary translation is, of course, even wider in many cases and not necessarily linked to a change in the purpose of the translation. Toury’s Descriptive Translation Studies has shown us how important the norms of reception are and how these norms can vary according to time and place.   RB: How do you deal with a term with several different shades of meaning in the original language? MR: Even specialist terms can be ‘perspectivised’ in different ways in a text, depending on which characteristics of the concept (as specified in an intensional definition, for example are activated by the co-text. The translator’s job is to establish whether there is a similar affordance for such nuancing in the target language e.g. by researching model texts with similar content and design features to those of the source text, or by communicating with experts working in the relevant field. In the latter case, however, we always need to be prepared for puzzled reactions and sometimes poor insight into actual practice. These kinds of differences are rarely recorded in codified sources such as termbases or dictionaries, as they are often highly contextualised and therefore present difficulties for the abstraction that is necessary for codification.  If no immediate solution is apparent in the target language, perhaps the nuancing is not necessary or poses no problems for target-language readers. Examples of this kind of nuancing can, however, be found in Rogers 1999; 2007.   RB: Do you think that translation can be a rich source of