Sample records for andetu mesuusataja dario

  1. The Composition of Experience in the Musical-Holistic Art of Dario Buccino

    Directory of Open Access Journals (Sweden)

    Stefano Lombardi Vallauri


    Full Text Available Nowadays music is no longer exclusively a performative art: as in the case of electronic music, it can also be produced completely by means of technology, without the live bodily action of an instrumentalist. With respect to this aesthetic paradigm, the Italian composer Dario Buccino (Rome, 1968 does exactly the opposite, creating a music which is even hyper-performative, in that it increases to the highest degree the requirements regarding the performing subject's awareness and free intentionality, and minimizes (human automaticity. To this end he has developed an original notation system, with many graphical ad hoc solutions, where musical symbols are integrated with indications about the proprioceptive attitude and the physical actions of the performer (often kindred to those of experimental theatre, dance, and body art, above all about the experiences to be felt when playing. Buccino goes farther on the way of Karlheinz Stockhausen's "intuitive music" (about 1968-70, Dieter Schnebel's Maulwerke (1968-74, Helmut Lachenmann's "musique concrète instrumentale", Brian Ferneyhough's extreme demand for effort, and radicalises an approach which instead is typical of other musical genres, where form at all levels arises in composition (often extemporaneous from the singular physical relationship of the interpreter with the instrument. 

  2. Disability and deviance: Dario Argento's Phenomena and the maintenance of abledness as a critical framework. (United States)

    McDaniel, Jamie L


    This exploration of disability directly applies Campbell's understanding of "abledness" to the film Phenomena by Italian director Dario Argento. Phenomena (1985) explores, through the diegetic response to protagonist Jennifer Corvino's ability to communicate with insects, the shifting cultural association between disability and deviance. The film begins with the traditional response to disability, what education psychologist Kaoru Yamamoto considers the cultural importance of classifying and interpreting disabled bodies by fitting them into a narrative of deviance for surveillance and control. Throughout Argento's film, characters attempt to classify Jennifer; scientists seek to diagnose her "affliction" through the medical model of disability, while Jennifer's schoolmistresses interpret Jennifer's behavior as a disciplinary problem based in environmental factors. This represents the structural model of disability, but in each instance, the attempt to classify Jennifer fails to diagnose or discipline the supposed "deviant, disabled body." Through this failure, the film dramatizes contemporary critiques of traditional models that examine disability, moving beyond to explore what Fiona Kumari Campbell has called "the maintenance of abledness" in sexed, raced, and modified bodies. By normalizing Jennifer's ability, then, Phenomena offers a framework for examining the process through which elements of "abledness" become normalized, a concept which many theorists now argue should maintain the focus of disability studies.

  3. Time fluctuations in the response of photomultiplier tubes Dario 56 AVP, XP 1021, XP 1210

    International Nuclear Information System (INIS)

    Breuze, G.; Sawine, P.


    The authors have studied experimentally the intrinsic time resolving power of 3 photomultiplier tubes, Dario 56 AVP, XP 1021, XP 1210 at various excitation levels produced by a source of short light pulses. They show, in agreement with present theories, that there exists an optimal resolving power for a certain trigger threshold, and they check the law governing the variations of this resolving power with the average number of photo-electrons emitted by light pulse, up to the limiting case of a single photo-electron. The results obtained show the progress which has been made by the constructor between the 56 AVP and the XP 1210 models: for 100 photo-electrons per pulse, for example, the times of resolution are 260 x 10 -12 s and 75 x 10 -12 s respectively; whereas the rise time for the anode pulses decreases from 2,3 to 1,2 x 10 -9 s. The intermediate tube XP 1021 has also a particularly good performance with respect to the 56 AVP, which it resembles very much both in its price and by its outer aspect. The authors stress finally the difficulties encountered in measuring with accuracy the time characteristics of PM as fast as the XP 1210, and in particular the limitation imposed by the light source. (author) [fr

  4. Education in Parana in the teachers’ formation process in republican Brazil: the contribution of the compendium of pedagogy by Dario Vellozo - doi: 10.4025/actascieduc.v34i2.18295

    Directory of Open Access Journals (Sweden)

    Marlete dos Anjos Silva Schaffrath


    Full Text Available The work has a result the study on the Compendium of Pedagogy (1907 by Dario Vellozo (1869-1937, teacher of Ginasio Paranaense and Escola Normal de Curitiba. The Compendium of Pedagogy by Vellozo was published in 1907 and republished in 1975. It was organized in three parts, one for every year of Teachers’ School. The article refers to the first book of the collection. In the first part of that book, there are ten lessons which covers the Pedagogy subject and their methods, organization of school and definitions of educations, as well as several lessons about Ancient, Medieval and Modern History and the prevailing educational thought in each one of them. The book for the second year, which was also organized in ten lesson, emphasizes the teaching methods, didactics, and physical education (health, moral, intellectual aspects. For the third year of course, Vellozo writes lessons about science, geography, history, drawing, music and a special lesson about kindergartens. The Compendium follows the scientific logics that should guide the school practices in that historical period, but also reflects the current culture in Teachers’ School, as well as  it shows the social-economic, political and cultural influences in Brazil and in Parana.  

  5. Alexander and Darius in a contest of wit («Alexander romance» 1.36-38: sources, formation, and storytelling traditions

    Directory of Open Access Journals (Sweden)

    Ioannis M. Konstantakos


    Full Text Available La storia dei doni simbolici inviati da Dario a Alessandro Magno (Romanzo di Alessandro 1.36-38 è derivata da una raccolta ellenistica di lettere fittizie che raccontavano la spedizione del conquistatore Macedone. Un modello diretto di quella narrazione fu la leggenda sui regali enigmatici mandati dagli Sciti a Dario I, che è narrata da Erodoto (4.131-132 e altre fonti ed era ben nota nell’epoca ellenistica. Oltre a questo, la storia di Alessandro e Dario è anche influenzata da tradizioni orali di folclore e divertimento, ugualmente riconducibili all’età ellenistica. Il re Persiano e quello Macedone competono nell’offerta di spiegazioni contrastanti degli oggetti simbolici; le loro spiegazioni sono collocate in una sorta di scala ascendente dal più debole al più forte. Secondo l’interpretazione di Alessandro, gli oggetti rappresentano le nozioni di potere e di conquista, superando in tal modo l’allegoria più debole di puerilità e sottomissione proposta da Dario. Questo schema narrativo ricorda giochi di enigmi con analoga struttura a gradi, che vengono attestati da Difilo e Clearco di Soli per simposi di prima età ellenistica. In tali gare scherzose, due o più giocatori tentavano di superarsi l’un l’altro, trovando ogni volta una soluzione più forte per lo stesso indovinello.

  6. Ai, nad torkasid mind keelega! / Anneli Saro

    Index Scriptorium Estoniae

    Saro, Anneli, 1968-


    Dario Fo "Müsterium buff" Tartu Sadamateatris Viljandi Kultuuriakadeemia teatrikunsti õppetooli kolmanda kursuse ehk kuuenda lennu tudengite esituses. Näitemängu on lavastanud Peeter Raudsepp. Esietendus 25. apr

  7. Pop & rock / Berk Vaher

    Index Scriptorium Estoniae

    Vaher, Berk, 1975-


    Uute heliplaatide Redman "Malpractice", Brian Eno & Peter Schwalm "Popstars", Clawfinger "A Whole Lot of Nothing", Dario G "In Full Color", MLTR e. Michael Learns To Rock "Blue Night" lühitutvustused

  8. Kuningal on külm / Kadi Herkül

    Index Scriptorium Estoniae

    Herkül, Kadi


    Dario Fo 'Elizabeth - naine juhuse tahtel', lavastaja Elmo Nüganen, esietendus Linnateatris 21. sept. 1996. Jaan Kruusvalli 'Hullumeelne professor, tema elukäik', lavastaja Mikk Mikiver, esietendus Draamateatris 21. sept. 1996

  9. Kompott õudusfilmifestivalil / Jaan Franclin Perlitz

    Index Scriptorium Estoniae

    Perlitz, Jaan Franclin


    Haapsalu õudusfilmifestivali filmidest : Fr. W. Murnau "Nosferatu - õuduste sümfoonia" (Saksamaa, 1922), Lõuna-Korea "R-Point", Takashi Miike "Izo" (Jaapan, 2004), itaallase Dario Argento "Ohked" ("Suspiria"), Eesti lühifilm "Hirm"

  10. Kartina mira skvoz Monokl / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-


    Sankt-Peterburgis toimus III rahvusvaheline monoetenduste festival Monokkel 2001, Eestit esindas Vene Draamateatri lavastus - Dario Fo "Ootan sind, kallim" (näitleja Ljubov Agapovaga), mis võeti soojalt vastu, kuid auhinda ei pälvinud

  11. Los rostros de Ana: Tres comentarios sobre Darío Morales

    Directory of Open Access Journals (Sweden)

    Paul Marcelo Velázquez Sabogal


    Full Text Available El presente escrito es una aproximación a la obra del artista colombiano Darío Morales desde la perspectiva dialéctica “vida-muerte”, alentada por el acontecimiento de lo ambiguo y sus implicaciones en la deconstrucción de una corporeidad estable regida por parámetros sociales, jurídicos y biológicos que desembocan en la caracterización de un “otro” en el cual se encuentran figuras como el anormal, el incorregible, el monstruo. Desde ellos pretendo trazar un punto de vista sobre aquellos Rostros de Ana donde se manifiestan figuras como el onanista y la vampira, para desembocar en un comentario que amplíe el espectro de sentido alrededor la obra del artista cartagenero. Palabras claves Cuerpo ambiguo, vida-muerte, sagrado-profano, onanismo. Ñawekuna kai warmi Ana Sutipa: Kimsa pariai ksi runa Dario Morales Sugllapi Kai kilkai kame ñalla regcha kai tacha runa colombiano Dario Morales Kilkakasina rimangapa “ kausai- wamui” aida chingapa kaikuna Mana allilla llugsichu tukuikunamanda icharichu llanga “sug manda” Kaipe turrerreme ¡ kauancheme man aillakaska, man allilla rurasla! Kirú. Kaipi pudenchi kauanga imasami kauacheca kai warme Ana paipa ñawekuna Kai ruraikuna sutikame onanista Chasallata vampira, Kaiwa munakume Allilla intendechengapa imasame parlaku sug iacha Cartagenero. Ima suti Rimai Simi: Cuerpo ambiguo, kaugsai, muerte, sagrado - profano, onanismo. The Faces of Ana: Three Comments on Dario Morales Abstract This paper is an approach to the work of Colombian artist Dario Morales from the perspective of the dialectic of “life and death”, encouraged by the occurrence of the ambiguous and its implications for the deconstruction of a stable corporeality governed by social, legal and biological parameters that lead to the characterization of an “other”, in which figures such as the abnormal, the incorrigible, the monster are to be found. From them, I intend to plot a point of view on those faces of Ana

  12. stage/page/play

    DEFF Research Database (Denmark)

    context. Contributors: Per Brask, Dario Fo, Jette Barnholdt Hansen, Pil Hansen, Sven Åke Heed, Ulla Kallenbach, Sofie Kluge, Annelis Kuhlmann, Kela Kvam, Anna Lawaetz, Bent Flemming Nielsen, Franco Perrelli, Magnus Tessing Schneider, Antonio Scuderi. stage/page/play is published as a festschrift...

  13. Pigem klaas kihisevat kui Ferrari / Sathnam Sanghera ; tõlk. Erik Aru

    Index Scriptorium Estoniae

    Sanghera, Sathnam


    Autor kirjeldab oma kohtumist Ferrari peatestisõitja Dario Benuzziga ja GlaxoSmithKline'i mustsõstrajoogi Ribena maitsja Isobel Hoare'iga ning järeldab, et võib teha tööga rahulolu olemusest järeldusi, mida eksperdid ei näi märkavat

  14. Kuues lend / Rait Avestik

    Index Scriptorium Estoniae

    Avestik, Rait, 1974-


    Tartu Ülikooli Viljandi kultruuriakadeemia teatrikunsti VI lennu diplomilavastused: Dario Fo "Müsterium buff", lavastaja Peeter Raudsepp; Anton Tshehhovi "Kolm õde", lavastaja-koreograaf Oleg Titov; Janusz Glowacki "Fortinbras jõi end täis", lavastajad Kalju Komissaarov ja Sven Heiberg. Lühidalt uutest diplomeeritud lavastajatest - Jaanika Juhanson ja Kati Kivitar

  15. "Blue-Collar Blues" uurib töösuhteid uutes oludes / Janar Ala

    Index Scriptorium Estoniae

    Ala, Janar, 1979-


    Tööproblemaatikat käsitlev näitus "Blue-Collar Blues" Tallinna Kunstihoones ja Tallinna Kunstihoone galeriis 31. jaanuarini 2010, kuraator Anders Härm. Lähemalt belgia-mehhiko kunstniku Francis Alys'e videost, austria kunstniku Oliver Ressleri ning venetsueela-saksa politoloogi Dario Azzelini videost "Viis tehast. Tööliste kontroll Venezuelas"

  16. Browse Title Index

    African Journals Online (AJOL)

    Items 501 - 550 of 823 ... Dario Kuron Lado. Vol 14, No 1 (2009), Patterns of spinal injury in a new neurosurgical centre: A 2-year prospective study, Abstract PDF. JKC Emejulu, OC Ekweogwu, Timothy Nottidge. Vol 18, No 2 (2013), Patterns of Traumatic Intracranial Bleeds at Kenyatta National Hospital in Nairobi, Kenya ...

  17. Cine club

    CERN Multimedia

    Ciné club


    Wednesday 15 April 2015 at 20:00CERN Council Chamber The Cat o’ Nine Tails (Il gatto a nove code) Directed by Dario Argento (Italy, 1971) 112 minutes   Franco Arno is a blind man that lives with his young niece and makes a living writing crossword puzzles. One night, while walking on the street, he overhears a weird conversation between two men sitting in a car parked in front of a medical institute where genetic experiments are performed. The same night someone breaks in the institute and knocks out a guard. Arno decides to investigate with the help of reporter Carlo Giordani. Original version Italian; English subtitles   Wednesday 22 April 2015 at 20:00CERN Council Chamber Four Flies on Grey Velvet (4 mosche di velluto grigio) Directed by Dario Argento (Italy, 1971) 104 minutes Roberto, a drummer in a rock band, keeps receiving weird phone calls and being followed by a mysterious man. One night he manages to catch up with his persecutor and tries to get him to t...

  18. Constitutive Parameters of Metamaterial Structures Used for Invisible Cloak Realization (United States)


    Sipus Dario Bojanjac Marko Bosiljevac Fakultet Elektrotechnike I Racunarstva Unska 3 Zagreb 10000 Croatia EOARD Grant 12-2080...Racunarstva Unska 3 Zagreb 10000 Croatia 8. PERFORMING ORGANIZATION REPORT NUMBER N/A 9. SPONSORING/MONITORING AGENCY NAME(S) AND...University of Zagreb Unska 3 Zagreb , HR-10000, Croatia 13 October 2013 Distribution A: Approved for public release; distribution is

  19. Language Identification by Statistical Analysis (United States)


    1520. Dario, Ruben, Azul (El rey burgues). Diaz,del Castillo, Bemal, The Imprisonment of Moctezuma. Fernandez dc Lizardi, Jose Joaquin, El...poriquillo sarniento. Garcia Calderon, Francisco, La creacion de un continente. Garcilaso de la Vega, El Inca, Comentarios reales de los incas. Gonzalez...Facundo. Siguenza y Gongora, Carlos de, Infortunios de Alonso Rameriz. Ugarte, Manuel, El destino de un contincnte (La ncuva Roma). Vasconcelos

  20. The Operational Capability of the American Expeditionary Forces in the World War (United States)


    attend the Advance Military Studies Program, COLs Michael Getchell, John Marr, and John Norris . Finally, to my college mentor, Dario Lorenzetti, killed...the United States Army and the War Department was selecting a general to lead the American Army in France. Since the end of the Spanish -American...formation since the end of the Spanish -American War. This proved to be a great challenge for the American Army in finding leaders to command the large

  1. Translations on Narcotics and Dangerous Drugs, Number 278 (United States)


    Trafficker Arrested k^ MEXICO Addiction Among Mexican Youths Discussed (ismael Mercado Andrews; EL DIA, 31 Oct 76) k6 Police Uncover Heroin Ring...were arrested. These men were released 2 days later at the order of the 2d Municipal Criminal Judge, Dario Leon Perez. This decision has been the...ILUSTRADO) 31 Oct 76 pp 2, 3 [Article by Ismael Mercado Andrews] [Text] Guido Belsasso, director of the Mexican Center for Drug Dependency

  2. Comparative study on system requirements and success factors of telemedicine solutions in resource-poor settings


    Dawson, Joanna Adobea


    Rationale: Attempts to successfully develop telemedicine solutions by specifying the require-ments and critical success factors of these solutions are on-going in sub-Saharan Africa (SSA) countries as a means of improving access to high-quality healthcare. European Space Agency (ESA) (Dario et al. 2005) have explored the challenges and benefits of telemedicine solutions in these regions in the domains of eGovernment such as billing and administrative data management to support the healthcare ...

  3. "Wars are not something accidental, nor are they due to bad characters"


    Azzellini, Dario; Marichal, Juan Diego


    Interview with Dario Azzellini, author of The Business of War and the new documentary film, Comuna Under Construction. What is it about Venezuela that is so interesting? Since 2003 I have practically lived in Venezuela. What motivates me is that I am interested in the social transformation process happening here. It’s a different type of revolution, a new left that draws from all the experiences of the 60s, 70s, 80s and 90s. ...

  4. The Trans-Sahara Counterterrorism Partnership: Strategy and Institutional Friction (United States)


    unauthorized commitments‖ (e.g., making a verbal contract to set up a banquet at an Iranian restaurant for $2,000) because they are illegal under...East Report N°29, 30 July 2004, 14 25 13 Ibid. 14 Lianne Kennedy-Boudali, ―The GSPC: Newest Franchise in al-Qa‘ida‘s Global Jihad,‖ The... Franchise in al-Qa‘ida‘s Global Jihad,‖ and Hanson and Vriens for estimates of GIA, GSPC and AQIM numbers. 25 Ibid. 26 Dario Cristiani, ―Algeria‘s

  5. Nanomedicine in diagnostics

    CERN Document Server

    Rozlosnik, Noemi


    Biased Diffusion and Rectified Brownian Motion at the Nanoscale Driving Mobile Sensing Automata for the Early Diagnosis of Endogenous DiseasesDario Narducci and Gianfranco CerofoliniBiotechnology-Utilized Nanopore for Single-Molecule InvestigationJi Wook Shim and Li-Qun GuSelf-assembled Peptide and Protein Nanostructures in DiagnosisJaime Castillo-León, Yuri Belotti, and Winnie E. SvendsenElectrochemical Sensor Systems for MedicineV. V. Shumyantseva, E. V. Suprun, T. V. Bulko, Ya. M. Chalenko, and A. I. ArchakovCon

  6. Deep Red (Profondo Rosso)

    CERN Multimedia

    Cine Club


    Wednesday 29 April 2015 at 20:00 CERN Council Chamber    Deep Red (Profondo Rosso) Directed by Dario Argento (Italy, 1975) 126 minutes A psychic who can read minds picks up the thoughts of a murderer in the audience and soon becomes a victim. An English pianist gets involved in solving the murders, but finds many of his avenues of inquiry cut off by new murders, and he begins to wonder how the murderer can track his movements so closely. Original version Italian; English subtitles

  7. Barrera del desempeño laboral


    María Del Rosario Alvarez-Ramirez


    El estres es un hecho complejo en la vida de toda persona con efectos distintos en cada quien, que no puede ser evitada ya que en todos lo momentos de la vida se esta en riesgo de presentarlo ante cualquier situacion, o una actividad laboral o familiar, que puede llegar a generar cualquier cambio que represente estres. Los sucesos negativos, dario, enfermedad o muerte de un ser querido, son hechos estresantes, asi como los sucesos positivos; ascender en el trabajo trae consigo el estres del n...

  8. Unusually Gothic : Robert Sigl's Laurin (1987)


    Stiglegger, Marcus


    Marcus Stiglegger revives a lost Gothic treasure in this brief discussion of Robert Sigl's Laurin—a rare case of German genre film-making and the heir to FW Murnau's legacy. Phantastic genre cinema is very rare in contemporary Germany—especially in the 1980s, the time when Italian horror reached another peak with Dario Argento's Opera (1985). The cliché of the German "easy comedy" ruled mainstream film production at the time, and so it appeared a kind of miracle when 27-year-old writer/direct...

  9. How Spatial is a Whale? Places and Processes in Zoomusicology / Dario Martinelli

    Index Scriptorium Estoniae

    Martinelli, Dario


    Zoomusikoloogiast, mis uurib loomade muusikalist tegevust. Loomade muusikataoliste häälitsuste uurimisest. Heli kasutamisest loomadevahelises kommunikatsioonis, muusikast kui imitatsiooni vormist. Muusikast kui sotsiaalsest faktist

  10. Djævelens billede

    DEFF Research Database (Denmark)

    Holm, Bent

    Det mest seriøse og inspirerende analytiske ridt, man kan finde blandt de utallige værker, der er skrevet om vor kulturs teater, forestillinger og scene. – Dario Fo Djævelens billede giver et kalejdoskopisk indblik i maskernes magt og magtens masker. Den går bag kulisserne i den iscenesatte virke...... eller mindre fiktive paver, biskopper, sultaner, kejsere, konger og komedianter i selskab med Harlekin, Pulcinella, Othello og Jeppe på Bjerget – i stadige styrkeprøver mellem ophøjet og grotesk, helligt og profant, seriøst og satirisk. Den karnevaleske masketradition – forvaltningen af...

  11. Diavolo di una particella perchè il bosone di Higgs cambierà la nostra vita

    CERN Document Server

    Menasce, Dario


    Lo scienziato del Cern Dario Menasce ha partecipato direttamente agli esperimenti che hanno condotto alla scoperta del Bosone di Higgs, ma , prima di condurre il lettore all'interno dell'LHC e dei suoi misteri, con coinvolgimento e grande serietà guida il lettore attraverso i momenti più importanti delle ricerche della fisica tramite l'intervento dei grandi scienziati del passato e del presente, che hanno infine permesso di arrivare a definire il Modello Standard delle particelle, il primo passo verso l'ipotetica Teoria del Tutto. Un testo molto utile per chi vuole sondare il mondo dell'ultrasottile, che riprendo in più occasioni anche come manuale di consultazione e approfondimento.


    Directory of Open Access Journals (Sweden)

    Elsa Díaz Santana


    Full Text Available Este estudio evalúa hasta qué grado el cuerpo médico del Hospital Dr. Darío Contreras de República Dominicana conoce, respeta, informa y aplica la Ley General de Salud, con relación al derecho del paciente Testigo de Jehová de negarse a ser transfundido (respeto a su autonomía. También si los Testigos de Jehová conocen la Ley General de Salud y hasta qué grado se han beneficiado con la puesta en marcha de la misma. El estudio reveló que ni médicos ni Testigos de Jehová conocen suficientemente dicha ley.Este estudo avalia quanto o corpo médico do Hospital Dr. Darío Contreras de República Dominicana conhece, respeita, informa e aplica a Lei Geral de Saúde em relação aos direitos do paciente Testemunha de Jeová de negar-se a ser transfundido (respeito a sua autonomia; também se os Testemunhas de Jeová conhecem a Lei Geral de Saúde e até que ponto têm se beneficiado diante dessa proposição. O estudo revelou que nem médicos, nem Testemunhas de Jeová conhecem de fato essa lei.This study evaluates up to which degree physicians of Hospital Dr. Dario Contreras of Dominican Republic know, respect, inform and apply the General Health Law in relation to the right of Jehovah witness patients to refuse being blood transfused (respect to their autonomy. It also evaluates whether Jehovah witnesses know General Health Law and in which degree they have been benefited by putting it into practice. The study reveals that Jehovah Witnesses do not know the law.

  13. Itinerarios textuales del "Quijote" en América (siglos XVII a XIX

    Directory of Open Access Journals (Sweden)

    Eva Marìa Valero Juan


    Full Text Available Starting with a brief description of the journey taken by the first editions of the Quixote which were sent to America, this article aims to review the textual biography of don Quixote in America between the 17th and 19th centuries. This selective review starts with the accounts of popular festivities that give evidence of the first appearances of don Quixote and Sancho in the texts. The selection of texts goes from 1607 to the Spanish Emancipation century, paying particular attention to its final years, with the analysis of some of the texts that Ruben Dario devoted to the Quixote, and of the rise of Don Quixote as a Spanish American symbol of identity.

  14. Tudengiteatrite vaim ja vaev : üliõpilasteater peaks olema julgem: pole ju midagi kaotada, võita aga on palju / Rait Avestik

    Index Scriptorium Estoniae

    Avestik, Rait, 1974-


    17.-19. veebr. Viljandis toimunud üliõpilasteatrite festivalist, millest võtsid osa Tartu Üliõpilasteater : S. Kane "Puhastatud", lavastaja Kalev Kudu ; TÜ Pärnu kolledži üliõpilasteater K-äng2 : kohvikuprogramm "Maailma lõpus on kohvik" ; TÜ Viljandi Kultuuriakadeemia üliõpilased (mitte näitlejasuuna õppurid) : lavaline kompositsioon "Actus interruptus" ; Tallinna Tehnikaülikooli T-teater : Kurt Wonneguti "Õnne sünnipäevaks, Wanda June!", lavastaja Tamur Tohver ning Tallinna Ülikooli Tudengiteater : John Boynton Priestley "Nad tulid linna", lavastaja Juta Terali. Eraldi vaadeldakse TÜ Viljandi Kultuuriakadeemia 3. kursuse näitekunsti tudengite tööd : Dario Fo "Müsteerium Buff", lavastaja Peeter Raudsepp

  15. The cultural policy in Italy and the innovations of the XXI century

    Directory of Open Access Journals (Sweden)

    Olimpia Niglio


    Full Text Available The paper analyzes the development of the first experiences of the sixteenth century cultural policy in Italy until the beginning of the twenty-first century with the institutional reform initiated by the Minister Dario Franceschini. In the pre-unification State it has been many important contributions of several local rulers who imposed conservation policies to prevent the dispersal of works of art. After the unification of Italy (1861 the laws of protection of the national heritage have helped to initiate the first important initiatives that have developed in practice only at the end of the twentieth century. Great institutional innovations and regulatory activated in the twenty-first century and of which this paper provides some important insights and deepening.

  16. Perioperative management of facial bipartition surgery

    Directory of Open Access Journals (Sweden)

    Caruselli M


    Full Text Available Marco Caruselli,1 Michael Tsapis,1,2 Fabrice Ughetto,1 Gregoire Pech-Gourg,3 Dario Galante,4 Olivier Paut1 1Anesthesia and Intensive Care Unit, La Timone Children’s Hospital, 2Pediatric Transport Team, SAMU 13, La Timone Hospital, 3Pediatric Neurosurgery Unit, La Timone Children’s Hospital, Marseille, France; 4Anesthesia and Intensive Care Unit, University Hospital Ospedali Riuniti of Foggia, Foggia, Italy Abstract: Severe craniofacial malformations, such as Crouzon, Apert, Saethre-Chotzen, and Pfeiffer syndromes, are very rare conditions (one in 50,000/100,000 live births that often require corrective surgery. Facial bipartition is the more radical corrective surgery. It is a high-risk intervention and needs complex perioperative management and a multidisciplinary approach. Keywords: craniofacial surgery, facial bipartition surgery, craniofacial malformations, pediatric anesthesia

  17. New ATLAS Software & Computing Organization

    CERN Multimedia

    Barberis, D

    Following the election by the ATLAS Collaboration Board of Dario Barberis (Genoa University/INFN) as Computing Coordinator and David Quarrie (LBNL) as Software Project Leader, it was considered necessary to modify the organization of the ATLAS Software & Computing ("S&C") project. The new organization is based upon the following principles: separation of the responsibilities for computing management from those of software development, with the appointment of a Computing Coordinator and a Software Project Leader who are both members of the Executive Board; hierarchical structure of responsibilities and reporting lines; coordination at all levels between TDAQ, S&C and Physics working groups; integration of the subdetector software development groups with the central S&C organization. A schematic diagram of the new organization can be seen in Fig.1. Figure 1: new ATLAS Software & Computing organization. Two Management Boards will help the Computing Coordinator and the Software Project...

  18. CERN and the 10,000th application of the WorldFIP protocol

    CERN Multimedia


    On 24 April, CERN received an award for the 10,000th application of the WorldFIP industrial communication network protocol. The award was presented to Juan Antonio Rubio, Head of CERN's ETT Division, by Marc Desjardins, President of the WorldFIP association, which groups together 430 industrial partners with the aim of promoting the WorldFIP concept. Marc Desjardins, President of the WorldFIP association, presenting the award for the 10,000th application to CERN ETT Division Leader Juan Antonio Rubio. From left to right: Guy Baribaud (CERN), Ercole Gallacio (WF), Noël Fayard (WF), Gérard Demars (WF), Dario Fantoni (WF), Marc Desjardins (WF), Raymond Brun (CERN), Jean-Pierre Hauet (WF), Juan Antonio Rubio (CERN), Bernard Jouga (WF), Raymond Rausch (CERN), Jean-Pierre Froidevaux (WF), Marilena Streit-Bianchi (CERN), Michel Rabany (CERN), Patrick Chatelet (WF), Nicolas Cravoisy (WF), Jean Bergeal (WF). Communication networks, also known as fieldbuses, provide for digital comunication betwe...

  19. Touching base with OPERA

    CERN Multimedia

    CERN Bulletin


    Three seminars – at CERN, at Gran Sasso and in Japan – and an article calling for the scrutiny of the scientific community: the OPERA Collaboration opened its research publicly. In addition to huge press coverage, this triggered welcome reactions from colleagues around the world, many of whom will attempt to independently interpret and reproduce the measurement. OPERA’s Spokesperson touches base with the Bulletin.   The CERN Main Auditorium was crowded as OPERA Physics co-ordinator Dario Autiero presented the results of their research (23 September 2011). According to the OPERA strategy, the results of the measurements are in the hands of the scientific community and, as for any other scientific result, several months will be needed before other groups will be able to perform an independent measurement. In the meantime, the OPERA Collaboration is dealing with an avalanche of emails from the scientific community, members of the general public, and the press. &...

  20. Academic Training Lectures | Representing Scientific Communities by Data Visualization | 14-15 March

    CERN Multimedia


    Please note that the next series of Academic Training Lectures will take place from 14 to 15 March 2016 and will be given by Dario Rodighiero (EPFL, Lausanne, Switzerland).   Representing Scientific Communities by Data Visualisation (1/2)​ Monday, 14 March 2016 from 11 a.m. to 12 p.m. Representing Scientific Communities by Data Visualisation (2/2)​ Tuesday, 15 March 2016 from 11 a.m. to 12 p.m. at CERN, IT Amphitheatre (31-3-004)  Description: These lectures present research that investigates the representation of communities, and the way to foster their understanding by different audiences. Communities are complex multidimensional entities intrinsically difficult to represent synthetically. The way to represent them is likely to differ depending on the audience considered: governi...

  1. Metabolic and inflammatory profiles of biomarkers in obesity, metabolic syndrome, and diabetes in a Mediterranean population. DARIOS Inflammatory study. (United States)

    Fernández-Bergés, Daniel; Consuegra-Sánchez, Luciano; Peñafiel, Judith; Cabrera de León, Antonio; Vila, Joan; Félix-Redondo, Francisco Javier; Segura-Fragoso, Antonio; Lapetra, José; Guembe, María Jesús; Vega, Tomás; Fitó, Montse; Elosua, Roberto; Díaz, Oscar; Marrugat, Jaume


    There is a paucity of data regarding the differences in the biomarker profiles of patients with obesity, metabolic syndrome, and diabetes mellitus as compared to a healthy, normal weight population. We aimed to study the biomarker profile of the metabolic risk continuum defined by the transition from normal weight to obesity, metabolic syndrome, and diabetes mellitus. We performed a pooled analysis of data from 7 cross-sectional Spanish population-based surveys. An extensive panel comprising 20 biomarkers related to carbohydrate metabolism, lipids, inflammation, coagulation, oxidation, hemodynamics, and myocardial damage was analyzed. We employed age- and sex-adjusted multinomial logistic regression models for the identification of those biomarkers associated with the metabolic risk continuum phenotypes: obesity, metabolic syndrome, and diabetes mellitus. A total of 2851 subjects were included for analyses. The mean age was 57.4 (8.8) years, 1269 were men (44.5%), and 464 participants were obese, 443 had metabolic syndrome, 473 had diabetes mellitus, and 1471 had a normal weight (healthy individuals). High-sensitivity C-reactive protein, apolipoprotein B100, leptin, and insulin were positively associated with at least one of the phenotypes of interest. Apolipoprotein A1 and adiponectin were negatively associated. There are differences between the population with normal weight and that having metabolic syndrome or diabetes with respect to certain biomarkers related to the metabolic, inflammatory, and lipid profiles. The results of this study support the relevance of these mechanisms in the metabolic risk continuum. When metabolic syndrome and diabetes mellitus are compared, these differences are less marked. Copyright © 2013 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved.

  2. Temperature behaviour of photo-emissive films. The case of photo-multipliers used in scintillation counters; Comportement en temperature des couches photoemissives. Cas des photomultiplicateurs utilises dans les compteurs a scintillations

    Energy Technology Data Exchange (ETDEWEB)

    Ardalan, A H [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires


    This work concerns the changes in the spectral sensitivity of 3 types of normal photo-cathodes (Cs{sub 3}Sb, tri-alkali and bi-alkali without cesium) as a function of temperature. The photo-cathodes of cathodes of commercial photomultipliers (DARIO, E.M.I., R.C.A., A.S.C.O.F.) were used for these tests. The temperature range studied was -25 C to +55 C (except for the bi-alkali photo-cathodes which were tested up to +150 C) and the wave-length range was 3250 to 7000 angstrom. After a brief review of photo-electric effect theories, the experimental device is described and the measurement results presented. Finally, an interpretation of these results is proposed. For the normal range of scintillator emission, i.e. between 3000 and 5000 angstroms (Na I (Tl), plastics, anthracene) the temperature coefficient is always negative: -0.15 % C for Cs{sub 3}Sb and up to -0.5 % C for the most temperature-sensitive photo-cathode. Above 5000 angstrom, the temperature coefficient of Cs{sub 3}Sb films becomes positive: +0.5 % C on the overage. The accuracy of the spectral sensitivity measurements is {+-}4 % in absolute value and {+-}1 % in relative value. (author) [French] Cette etude porte sur la variation de la sensibilite spectrale de 3 types de photocathodes usuelles (Cs{sub 3}Sb, trialcalines et bialcalines sans cesium) en fonction de la temperature. Des photocathodes de photomultiplicateurs du commerce (DARIO, E.M.I., R.C.A., A.S.C.O.P.) ont fait l'objet de ces essais. Le domaine examine s'etendait en temperature de -25 C a +55 C (sauf pour les photocathodes bialcalines qui ont ete portees a une temperature de +150 C) et en longueur d'onde de 3250 a 7000 angstrom. Apres un rappel des theories de l'effet photoelectrique, le dispositif experimental est decrit et les resultats des mesures exposes. Enfin, une interpretation de ces resultats est proposee. Dans le domaine de l'emission des scintillateurs usuels, c'est-a-dire entre 3000 et 5000 angstrom (Na I (Tl), plastiques

  3. U Tingiutu. Ajax in Calabria. Political Fissures in the Theatre of Scena Verticale

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    Angela Albanese


    Full Text Available The curse of Calabria is collusion. Collusion between the law of the state and the hidden law, between the power of public institutions and mafia power, between upright citizens and "la mala carne", the "evil flesh" of the criminal underworld. Director, actor and playwright Dario De Luca, guiding spirit with Saverio La Ruina of the Scena Verticale theatre company, shines a light on the criminal state within the state in his new play, U Tingiutu. Ajax in Calabria, in which he also performs along with four other actors. De Luca has transformed Sophocles's tragedy to illuminate the daily tragedy of gang warfare, street killings, and blood spilled in the name of honor, in the face of the cowardly inertia of those who pretend not to see. De Luca's Calabria is beseiged by 'ndrangheta power and drained by an ineffectual, often complicit political sector, its social fabric muddied and torn. The dynamics by which mafia violence insinuates itself into the shadowy corners of politics to seize control of the law are acutely revealed in the shadow zones of language, in the harsh, archaic dialect of the region, full of allusion, meaningful silence and glances.

  4. Gothic/Giallo/Genre: hybrid images in Italian horror cinema, 1956-82

    Directory of Open Access Journals (Sweden)

    Keith H Brown


    Full Text Available   Italian horror cinema is commonly divided into two periods and genres. An initial classical Gothic period spanned the years from 1956 to 1966 and was followed by a modern giallo (thriller period from 1970 to 1982. Whilst accepting this broad distinction, this paper seeks to add nuance by considering the hybrid elements of three key films by three of the most important directors working in the giallo and horror area, namely Riccardo Freda with I Vampiri (1956, Mario Bava with The Girl Who Knew too Much (1963 and Dario Argento with Deep Red (1975. Drawing in particular upon Nöel Carroll’s idea of “fearing fictions”, I contend that Freda’s film, the first Italian horror movie since the silent era, is notable for being a distinctively modern vampire film; that Bava’s film, a foundational giallo, may be seen as having a palimpsest in Jane Austen’s Gothic parody Northanger Abbey; and that Argento’s film, while often taken as the paradigmatic giallo, has supernatural horror elements that push it in the direction of the Gothic.

  5. Hybridization-based reconstruction of small non-coding RNA transcripts from deep sequencing data. (United States)

    Ragan, Chikako; Mowry, Bryan J; Bauer, Denis C


    Recent advances in RNA sequencing technology (RNA-Seq) enables comprehensive profiling of RNAs by producing millions of short sequence reads from size-fractionated RNA libraries. Although conventional tools for detecting and distinguishing non-coding RNAs (ncRNAs) from reference-genome data can be applied to sequence data, ncRNA detection can be improved by harnessing the full information content provided by this new technology. Here we present NorahDesk, the first unbiased and universally applicable method for small ncRNAs detection from RNA-Seq data. NorahDesk utilizes the coverage-distribution of small RNA sequence data as well as thermodynamic assessments of secondary structure to reliably predict and annotate ncRNA classes. Using publicly available mouse sequence data from brain, skeletal muscle, testis and ovary, we evaluated our method with an emphasis on the performance for microRNAs (miRNAs) and piwi-interacting small RNA (piRNA). We compared our method with Dario and mirDeep2 and found that NorahDesk produces longer transcripts with higher read coverage. This feature makes it the first method particularly suitable for the prediction of both known and novel piRNAs.

  6. Temperature behaviour of photo-emissive films. The case of photo-multipliers used in scintillation counters

    International Nuclear Information System (INIS)

    Ardalan, A.H.


    This work concerns the changes in the spectral sensitivity of 3 types of normal photo-cathodes (Cs 3 Sb, tri-alkali and bi-alkali without cesium) as a function of temperature. The photo-cathodes of cathodes of commercial photomultipliers (DARIO, E.M.I., R.C.A., A.S.C.O.F.) were used for these tests. The temperature range studied was -25 C to +55 C (except for the bi-alkali photo-cathodes which were tested up to +150 C) and the wave-length range was 3250 to 7000 angstrom. After a brief review of photo-electric effect theories, the experimental device is described and the measurement results presented. Finally, an interpretation of these results is proposed. For the normal range of scintillator emission, i.e. between 3000 and 5000 angstroms (Na I (Tl), plastics, anthracene) the temperature coefficient is always negative: -0.15 % C for Cs 3 Sb and up to -0.5 % C for the most temperature-sensitive photo-cathode. Above 5000 angstrom, the temperature coefficient of Cs 3 Sb films becomes positive: +0.5 % C on the overage. The accuracy of the spectral sensitivity measurements is ±4 % in absolute value and ±1 % in relative value. (author) [fr

  7. GMAG Dissertation Award Talk: Zero-moment Half-Metallic Ferrimagnetic Semiconductors (United States)

    Jamer, Michelle E.


    Low- and zero-moment half-metallic ferrimagnetic semiconductors have been proposed for advanced applications, such as nonvolatile RAM memory and quantum computing. These inverse-Heusler materials could be used to generate spin-polarized electron or hole currents without the associated harmful fringing magnetic fields. Such materials are expected to exhibit low to zero magnetic moment at room temperature, which makes them well-positioned for future spin-based devices. However, these compounds have been shown to suffer from disorder. This work focuses on the synthesis of these compounds and the investigation of their structural, magnetic, and transport properties. Cr2CoGa and Mn3Al thin films were synthesized by molecular beam epitaxy, and V3Al and Cr2CoAl were synthesized via arc-melting. Rietveld analysis was used to determine the degree of ordering in the sublattices as a function of annealing. The atomic moments were measured by X-ray magnetic circular and linear dichroism confirmed antiferromagnetic alignment of sublattices and the desired near-zero moment in several compounds. In collaboration with George E. Sterbinsky, Photon Sciences Directorate, Brookhaven National Laboratory; Dario Arena Photon Sciences Directorate, Brookhaven National Laboratory; Laura H. Lewis, Chemical Engineering, Northeastern University; and Don Heiman, Physics, Northeastern University. NSF-ECCS-1402738, NSF-DMR-0907007.

  8. Long term efficacy and safety of etanercept in the treatment of psoriasis and psoriatic arthritis

    Directory of Open Access Journals (Sweden)

    Kivelevitch D


    Full Text Available Dario Kivelevitch, Bobbak Mansouri, Alan Menter Department of Dermatology, Baylor University Medical Center, Dallas, TX, USA Abstract: Psoriasis is a chronic, immune-mediated inflammatory disease affecting both the skin and joints. Approximately 20% of patients suffer a moderate to severe form of skin disease and up to 30% have joint involvement. Standard therapies for psoriasis include topical medications, phototherapy, and both oral systemic and biological therapies whereas therapies for psoriatic arthritis include nonsteroidal anti-inflammatory drugs followed by disease modifying antirheumatic drugs and/or tumor necrosis factor (TNF-α inhibitors and interleukin-12/23p40 inhibitors. Treatment of both diseases is typically driven by disease severity. In the past decade, major advances in the understanding of the immunopathogenesis of psoriasis and psoriatic arthritis have led to the development of numerous biological therapies, which have revolutionized the treatment for moderate to severe plaque psoriasis and psoriatic arthritis. Anti-TNF-α agents are currently considered as first line biological therapies for the treatment of moderate to severe psoriasis and psoriatic arthritis. Currently approved anti-TNF-α agents include etanercept, adalimumab, and infliximab for psoriasis and psoriatic arthritis as well as golimumab and certolizumab for psoriatic arthritis. In this article, we aim to evaluate the long term safety and efficacy of etanercept in psoriasis and psoriatic arthritis. Keywords: psoriasis, psoriatic arthritis, etanercept, biological therapy, tumor necrosis factor, safety

  9. MEchatronic REspiratory System SImulator for Neonatal Applications (MERESSINA project: a novel bioengineering goal

    Directory of Open Access Journals (Sweden)

    Scaramuzzo RT


    Full Text Available Rosa T Scaramuzzo,1,2 Massimiliano Ciantelli,1 Ilaria Baldoli,3 Lisa Bellanti,3 Marzia Gentile,1 Francesca Cecchi,3 Emilio Sigali,1 Selene Tognarelli,3 Paolo Ghirri,1–4 Stefano Mazzoleni,3 Arianna Menciassi,3 Armando Cuttano,1 Antonio Boldrini,1–4 Cecilia Laschi,3 Paolo Dario3 1Centro di Formazione e Simulazione Neonatale "NINA," UO Neonatologia, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy; 2Istituto di Scienze della Vita, 3The BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy; 4Università di Pisa, Pisa, Italy Abstract: Respiratory function is mandatory for extrauterine life, but is sometimes impaired in newborns due to prematurity, congenital malformations, or acquired pathologies. Mechanical ventilation is standard care, but long-term complications, such as bronchopulmonary dysplasia, are still largely reported. Therefore, continuous medical education is mandatory to correctly manage devices for assistance. Commercially available breathing function simulators are rarely suitable for the anatomical and physiological realities. The aim of this study is to develop a high-fidelity mechatronic simulator of neonatal airways and lungs for staff training and mechanical ventilator testing. The project is divided into three different phases: (1 a review study on respiratory physiology and pathophysiology and on already available single and multi-compartment models; (2 the prototyping phase; and (3 the on-field system validation. Keywords: simulation, lung, newborn, continuous medical education, respiratory system

  10. GeneNetWeaver: in silico benchmark generation and performance profiling of network inference methods. (United States)

    Schaffter, Thomas; Marbach, Daniel; Floreano, Dario


    Over the last decade, numerous methods have been developed for inference of regulatory networks from gene expression data. However, accurate and systematic evaluation of these methods is hampered by the difficulty of constructing adequate benchmarks and the lack of tools for a differentiated analysis of network predictions on such benchmarks. Here, we describe a novel and comprehensive method for in silico benchmark generation and performance profiling of network inference methods available to the community as an open-source software called GeneNetWeaver (GNW). In addition to the generation of detailed dynamical models of gene regulatory networks to be used as benchmarks, GNW provides a network motif analysis that reveals systematic prediction errors, thereby indicating potential ways of improving inference methods. The accuracy of network inference methods is evaluated using standard metrics such as precision-recall and receiver operating characteristic curves. We show how GNW can be used to assess the performance and identify the strengths and weaknesses of six inference methods. Furthermore, we used GNW to provide the international Dialogue for Reverse Engineering Assessments and Methods (DREAM) competition with three network inference challenges (DREAM3, DREAM4 and DREAM5). GNW is available at along with its Java source code, user manual and supporting data. Supplementary data are available at Bioinformatics online.

  11. Effectiveness of cognitive behavioral therapy integrated with systematic desensitization, cognitive behavioral therapy combined with eye movement desensitization and reprocess­ing therapy, and cognitive behavioral therapy combined with virtual reality exposure therapy methods in the treatment of flight anxiety: a randomized trial

    Directory of Open Access Journals (Sweden)

    Triscari MT


    Full Text Available Maria Teresa Triscari,1 Palmira Faraci,2 Dario Catalisano,3 Valerio D’Angelo,1 Viviana Urso1 1Laboratory for Psychosomatic Disorders, Local Health Trust, Palermo, Italy; 2Faculty of Human and Social Sciences, University of Enna “Kore”, Enna, Italy; 3Italian Flight Safety Committee, Aeroporto di Fiumicino, Fiumicino (RM, Italy Abstract: The purpose of the research was to compare the effectiveness of the following treatment methods for fear of flying: cognitive behavioral therapy (CBT integrated with systematic desensitization, CBT combined with eye movement desensitization and reprocessing therapy, and CBT combined with virtual reality exposure therapy. Overall, our findings have proven the efficacy of all interventions in reducing fear of flying in a pre- to post-treatment comparison. All groups showed a decrease in flight anxiety, suggesting the efficiency of all three treatments in reducing self-report measures of fear of flying. In particular, our results indicated significant improvements for the treated patients using all the treatment programs, as shown not only by test scores but also by participation in the post-treatment flight. Nevertheless, outcome measures maintained a significant effect at a 1-year follow-up. In conclusion, combining CBT with both the application of eye movement desensitization and reprocessing treatment and the virtual stimuli used to expose patients with aerophobia seemed as efficient as traditional cognitive behavioral treatments integrated with systematic desensitization. Keywords: flight anxiety, fear of flying, aerophobia, cognitive behavioral therapy, EMDR, VRET 

  12. Barrera del desempeño laboral

    Directory of Open Access Journals (Sweden)

    María Del Rosario Alvarez-Ramirez


    Full Text Available El estres es un hecho complejo en la vida de toda persona con efectos distintos en cada quien, que no puede ser evitada ya que en todos lo momentos de la vida se esta en riesgo de presentarlo ante cualquier situacion, o una actividad laboral o familiar, que puede llegar a generar cualquier cambio que represente estres. Los sucesos negativos, dario, enfermedad o muerte de un ser querido, son hechos estresantes, asi como los sucesos positivos; ascender en el trabajo trae consigo el estres del nuevo status, de nuevas responsabilidades. Dentro de los trastornos clinicos vinculados al estres hay alteraciones como: trastornos del sumo, ulceras, dolores de cabeza, aceleracion del ritmo cardiaco y otros trastornos como los cardiovasculares: palpitaciones, hipertension arterial, trastornos digestivos, dolores, ardores, vomitos, nauseas, diarrea o estreriimiento y trastornos cutaneos: donde se presenta transpiracion de manos y pies y problemas alergicos. En el estres se pueden llegar a presentar dos tipos de estres: el positivo y el negativo. Los cuales presentan unas caracteristicas muy particulares, como en el estres negativo: una persona se encuentra ante un nitmero creciente de demandas que le plantean dificultad o constituyen una amenaza, se debe mirar el modo de afrontarlas. En el Estres positivo se presenta cuando la percepcion de capacidad de demanda es mucho mas amplia que las verdaderas demandas. Un aspecto fundamental ante la presencia de estres es la practica necesaria de un deporte o la realizacion de actividades recreativas.

  13. Chronotoxicity of contaminants (etanol and hezvy metales) in a freshwater teleost Dario rerio (Hamilton, 1882) and marine amphipods Gammarus aequicauda (Martynov, 1931) and Gammarus chevreuxi (Sexton, 1913) = Cronotixicidad de contaminantes (etanol y metales pesados) en el teleósteo de agua dulce Dario rerio (Hamilton, 1822) y los antípodos marinos, Gammarus aequicauda (Martynov, 1931) y Gammarus chevreuxi (Sexton, 1913)


    Bello Marín, Carolina


    Esta tesis tiene como objetivo investigar los efectos del etanol y metales pesados (cadmio y mercurio) en los patrones diarios de dos especies acuáticas clave: pez cebra (Darío rerio) y anfípodo gammarus (G. aequicauda y G. chevreuxi). La investigación se realizó en dos niveles organizativos: comportamental y molecular. Con este fin, hemos establecido cuatro objetivos específicos: 1. Investigar los efectos al etanol en el pez cebra en función en su ritmo circadiano. 2. Determinar la exi...

  14. Gift to Darius - Or on about the exhibition: mobility in printmaking procedures Dádiva a Dario - Ou sobre a exposição:mobilidade em processos de gravura

    Directory of Open Access Journals (Sweden)

    Ho Lihn Piuh


    Full Text Available Presentation of the exhibition "Mobility in the process of engraving," the artist in Iara Strobel Department of Culture Curitiba.There is this creative phenomenon, using a strategy he called "refraction" poetic, the Bakhtinian sense. The refraction through the verbal non-verbal, by hypothesis allows to manage a "language without language," though not without codes to be unveiled in the critical operation. Will, in this case, the very instrument of analysis requires a shift in bias reference for the poetic.Apresentação da exposição "Mobilidade em processos de Gravura", da artista plástica Iara Strobel na Secretaria de Cultura/Curitiba. Observa-se este fenômeno criativo, recorrendo a uma estratégia a que chamaria de "refração" poética, no sentido bakhtiniano. A refração do verbal através do não verbal, permite por hipótese gerenciar uma "linguagem sem língua", embora não isenta de códigos a serem desvelados na operação crítica. Tenciona, nesta ocorrência, o próprio instrumento de análise exigindo um deslocamento do pendor referencial para o poético.

  15. Algunas novelas de Darío Fernández-Flórez: de Zarabanda (1944 a Alta Costura (1954. Temas escabrosos en tiempos de restricciones moralistas

    Directory of Open Access Journals (Sweden)

    Montejo Gurruchaga, Lucía


    Full Text Available Dario Fernández-Flórez begins in 1944 with Zarabanda a narrative style of intellectual eroticism and inmoral atmosphere which attracted no attention. Six years later he published Lola, espejo oscuro the recollections of a high prostitute. The novel was an scandal and an immediate success. Although the topic and its treatment were odd at the time because the strict moral values which mantained Franco´s regime were ignored, the novel was published with no cuts at all. Censorship was deaf to all the voices that warned of its dangers. This had an explanation: Darío Fernández-Flórez held an important post in the Propaganda National Service. After his dismissal censors were less lenient.Darío Fernández-Flórez inicia en 1944 con Zarabanda una narrativa de erotismo intelectualizado y ambiente amoral que no tuvo ningún eco. Seis años después publicará Lola, espejo oscuro, las memorias de una prostituta de alto copete. La novela suscitó un gran escándalo y su éxito fue inmediato. Aunque el tema y su tratamiento eran inusitados en aquellos momentos porque la obra daba al traste con los estrictos valores morales que sustentaban el régimen franquista, la novela fue publicada sin recortes; la censura hizo oídos sordos a todas las voces que alertaban de su peligro. Este hecho tiene una explicación: Darío Fernández-Flórez ocupaba un cargo importante en el Servicio Nacional de Propaganda. Tras su cese, los censores serán menos benevolentes.

  16. II Luso-Brazilian Symposium - Hair Care and Health Proceedings

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    Joana Portugal Mota et al.


    Full Text Available II Luso-Brazilian Symposium - Hair Care and Health II Simpósio Luso-Brasileiro - Cuidados e Saúde do Cabelo 24 October | 24 Outubro Lisboa - Universidade Lusófona Honor Commitee /Comissão de Honra Magnífico Reitor da Universidade Lusófona, Mário Moutinho Presidente do Conselho de Administração da Universidade Lusófona, Manuel de Almeida Damásio Presidente do Infarmed, Eurico Castro Alves. Bastonário da Ordem dos Farmacêuticos, Carlos Maurício Barbosa Presidente da Associação Industriais Cosmética, Ana Maria Couras. Presidente da SPCC, Luís Monteiro Rodrigues (Presidente do Simpósio Presidente da ABC, João Hansen (Presidente do Simpósio Scientific Commitee /Comissão Científica Alberto Keidi Kurebayashi Catarina Fialho Rosado Celso Martins Júnior Joana Portugal Mota João Hansen Luís Monteiro Rodrigues Maria Lídia Palma Organizing Commitee /Comissão Organizadora SPCC Escola de Ciências e Tecnologias da Saúde (ECTS da U. Lusófona de Humanidades e Tecnologias ALIES – Associação Lusófona para o Desenvolvimento do Ensino e Investigação das Ciências da Saúde CBIOS – Centro de Investigação em Biociências e Tecnologias da Saúde Programa Open Session | Sessão de abertura Bastonário da Ordem dos Farmacêuticos, Carlos Maurício Barbosa Direcção da SPCC, Manuel Fitas Direcção da ABT, Celso Martins Júnior 1st Session | Sessão 1 HOT TOPICS (Tecnologia das Formulações Charmain | Moderador - Joana Portugal Mota Speakers | Prelectores Celso Martins Júnior Michelli Dario Key-note Speakers | Prelectores Bruno A. Bernard Nelson Tavares 2st Session | Sessão 2 HOT TOPICS (Saúde do Cabelo e Imagem Charmain | Moderador - André Rolim Baby Speakers | Prelectores Celso Martins Júnior Roundtable - Debate | Mesa Redonda - Debate Flávio Roques Catarina Rosado Previous speakers | Prelectores anteriores 1st Session | Sessão 1 HOT TOPICS (Formulation Technology | HOT TOPICS (Tecnologia das Formulações Chairman


    Directory of Open Access Journals (Sweden)

    Oliveira, Cláudio José de


    Full Text Available Este texto apresenta e discute os resultados finais de uma pesquisa que estudou a formação docente de egressos dos Cursos de Pedagogia, no período de 1995 até o ano de 2008, em relação aos processos de aprender e ensinar matemática nos Anos Iniciais do Ensino Fundamental (AIEF. A pesquisa também estudou a experiência de formação de estudantes-professoras matriculadas nas disciplinas de Linguagem Matemática na Educação I e II, nas edições de 2009 até 2011. Assim, o objetivo deste texto é discutir alguns efeitos da formação como experiência docente na produção de professores segundo uma lógica da informação, do repassar conteúdo e da formação de sujeitos da opinião. A produção dos dados foi realizada em duas etapas. Na primeira foi realizado um mapeamento dos egressos dos Cursos de Pedagogia que responderam dois questionários com questões objetivas e dissertativas. A tabulação e análise dos dados foram realizadas com as estudantes-professoras durante as disciplinas. Fez parte da segunda etapa um fórum de discussão na modalidade EAD. Na primeira etapa da pesquisa 40 egressos de Pedagogia responderam aos questionários e, na segunda, 30 alunas participaram do fórum de discussão. Os achados da pesquisa foram discutidos problematizando a formação docente como produtora de um professor informado de técnicas, um sujeito que tem pressa, que busca conhecer no tempo que dispõe as novidades apresentadas na e pela instituição formadora. Como resultados sublinhamos a intrínseca relação entre os saberes docentes e as práticas pedagógicas dos professores que ensinam matemática com as propostas dos “cursos de atualização” que lhes são oferecidos, impostos, sem avaliar os resultados destas ações. Na análise dos dados foram considerados os estudos de Maurice Tardif, Dario Fiorentini, Adair Nacarato, Jorge Larrosa, entre outros.This paper presents and discusses the final results of a research that

  18. Strangers in Stranger Lands: Language, Learning, Culture

    Directory of Open Access Journals (Sweden)

    Hong Li


    Full Text Available This study investigates international students’ perceptions of the issues they face using English as a second language while attending American higher education institutions. In order to fully understand those challenges involved in learning English as a Second Language, it is necessary to know the extent to which international students have mastered the English language before they start their study in America. Most international students experience an overload of English language input upon arrival in the United States. Cultural differences influence international students’ learning of English in other ways, including international students’ isolation within their communities and America’s lack of teaching listening skills to its own students. Other factors also affect international students’ learning of English, such as the many forms of informal English spoken in the USA, as well as a variety of dialects. Moreover, since most international students have learned English in an environment that precluded much contact with spoken English, they often speak English with an accent that reveals their own language. This study offers informed insight into the complicated process of simultaneously learning the language and culture of another country. Readers will find three main voices in addition to the international students who “speak” (in quotation marks throughout this article. Hong Li, a Chinese doctoral student in English Education at the University of Missouri-Columbia, authored the “regular” text. Second, Roy F. Fox’s voice appears in italics. Fox is Professor of English Education and Chair of the Department of Learning, Teaching, and Curriculum at the University of Missouri-Columbia. Third, Dario J. Almarza’s voice appears in boldface. Almarza, a native of Venezuela, is an Assistant Professor of Social Studies Education at the same institution.

  19. Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia

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    Capretto L


    Full Text Available Lorenzo Capretto1, Stefania Mazzitelli2, Eleonora Brognara2, Ilaria Lampronti2, Dario Carugo1, Martyn Hill1, Xunli Zhang1, Roberto Gambari2, Claudio Nastruzzi31Engineering Sciences, University of Southampton, Southampton, UK; 2Department of Biochemistry and Molecular Biology, 3Department of Pharmaceutical Sciences, University of Ferrara, Ferrara, ItalyAbstract: This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH, based on Pluronic® block copolymers, by a new microfluidic approach. The effect of different production parameters has been investigated for their effect on PM-MTH characteristics. The compared analysis of PM-MTH produced by microfluidic and conventional bulk mixing procedures revealed that microfluidics provides a useful platform for the production of PM-MTH with improved controllability, reproducibility, smaller size, and polydispersity. Finally, an investigation of the effects of PM-MTH, produced by microfluidic and conventional bulk mixing procedures, on the erythroid differentiation of both human erythroleukemia and human erythroid precursor cells is reported. It is demonstrated that PM-MTH exhibited a slightly lower toxicity and more pronounced differentiative activity when compared to the free drug. In addition, PM-MTH were able to upregulate preferentially γ-globin messenger ribonucleic acid production and to increase fetal hemoglobin (HbF accumulation, the percentage of HbF-containing cells, and their HbF content without stimulating α-globin gene expression, which is responsible for the clinical symptoms of ß-thalassemia. These results represent an important first step toward a potential clinical application, since an increase in HbF could alleviate the symptoms underlying ß-thalassemia and sickle cell anemia. In conclusion, this report suggests that PM-MTH produced by microfluidic approach warrants further evaluation as a potential therapeutic protocol

  20. ‘Your Brain on Art’: Emergent cortical dynamics during aesthetic experiences

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    Kimberly eKontson


    Full Text Available The brain response to conceptual art was studied with mobile electroencephalography (EEG to examine the neural basis of aesthetic experiences. In contrast to most studies of perceptual phenomena, participants were moving and thinking freely as they viewed the exhibit The Boundary of Life is Quietly Crossed by Dario Robleto at the Menil Collection-Houston. The brain activity of over 400 subjects was recorded using dry-electrode and one reference gel-based EEG systems over a period of 3 months. Here, we report initial findings based on the reference system. EEG segments corresponding to each art piece were grouped into one of three classes (complex, moderate, and baseline based on analysis of a digital image of each piece. Time, frequency, and wavelet features extracted from EEG were used to classify patterns associated with viewing art, and ranked based on their relevance for classification. The maximum classification accuracy was 55% (chance = 33% with delta and gamma features the most relevant for classification. Functional analysis revealed a significant increase in connection strength in localized brain networks while subjects viewed the most aesthetically pleasing art compared to viewing a blank wall. The direction of signal flow showed early recruitment of broad posterior areas followed by focal anterior activation. Significant differences in the strength of connections were also observed across age and gender. This work provides evidence that EEG, deployed on freely behaving subjects, can detect selective signal flow in neural networks, identify significant differences between subject groups, and report with greater-than-chance accuracy the complexity of a subject’s visual percept of aesthetically pleasing art. Our approach, which allows acquisition of neural activity ‘in action and context’, could lead to understanding of how the brain integrates sensory input and its ongoing internal state to produce the phenomenon which we term

  1. The tactical development of Achaemenid cavalry

    Directory of Open Access Journals (Sweden)

    Nefedkin, Alexander K.


    Full Text Available

    In the 6th and first half of the 5th century BC, Persian horsemen were armed with bows and javelins, and fought as a light cavalry. In the second half of the 5th century in the western regions of the Persian empire there was an increase in heavily-armoured cavalry, armed with the spears (palta for thrusting and throwing. I propose that this evolution is connected with the long wars against the Greeks and the deterioration of the morale quality of Persian warriors. The attempt of the last Persian king Darius III to re-arm his horsemen with lances to fight the Macedonian Companions did not succeed in saving the Achaemenid empire from collapse.

    En el siglo VI y la primera mitad del siglo V A. C. los caballeros persianos fueron armados con arcos y jabalinas y luchaban como caballeria ligera. En la segunda mitad del siglo V A.C. en las regiones occidentales del Imperio Persa se extienden caballeros de armadura pesada, armados con lanzas (palta, aunque la mayor parte de caballeria estaba formada con armados ligeramente. Segun mi opinion, estos cambios en caballeria persiana eston relacionados con la lenta guerra contra los griegos y tambien con empeoramiento de completacion de caballeria local. El intento de Dario III de rearmar a sus caballeros con las lanzas largas para luchar con exito con caballeria macedonica, fracaso por causa de caida del Imperio Aquemenido.

  2. MO-FG-CAMPUS-TeP3-01: A Model of Baseline Shift to Improve Robustness of Proton Therapy Treatments of Moving Tumors

    Energy Technology Data Exchange (ETDEWEB)

    Souris, K; Barragan Montero, A; Di Perri, D; Geets, X; Lee, J [Universite catholique de Louvain, Brussels (Belgium); Sterpin, E [Universite catholique de Louvain, Brussels (Belgium); KU Leuven, Leuven (Belgium)


    Purpose: The shift in mean position of a moving tumor also known as “baseline shift”, has been modeled, in order to automatically generate uncertainty scenarios for the assessment and robust optimization of proton therapy treatments in lung cancer. Methods: An average CT scan and a Mid-Position CT scan (MidPCT) of the patient at the planning time are first generated from a 4D-CT data. The mean position of the tumor along the breathing cycle is represented by the GTV contour in the MidPCT. Several studies reported both systematic and random variations of the mean tumor position from fraction to fraction. Our model can simulate this baseline shift by generating a local deformation field that moves the tumor on all phases of the 4D-CT, without creating any non-physical artifact. The deformation field is comprised of normal and tangential components with respect to the lung wall in order to allow the tumor to slip within the lung instead of deforming the lung surface. The deformation field is eventually smoothed in order to enforce its continuity. Two 4D-CT series acquired at 1 week of interval were used to validate the model. Results: Based on the first 4D-CT set, the model was able to generate a third 4D-CT that reproduced the 5.8 mm baseline-shift measured in the second 4D-CT. Water equivalent thickness (WET) of the voxels have been computed for the 3 average CTs. The root mean square deviation of the WET in the GTV is 0.34 mm between week 1 and week 2, and 0.08 mm between the simulated data and week 2. Conclusion: Our model can be used to automatically generate uncertainty scenarios for robustness analysis of a proton therapy plan. The generated scenarios can also feed a TPS equipped with a robust optimizer. Kevin Souris, Ana Barragan, and Dario Di Perri are financially supported by Televie Grants from F.R.S.-FNRS.

  3. Effects of balance training using a virtual-reality system in older fallers

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    Duque G


    Full Text Available Gustavo Duque,1,2 Derek Boersma,1 Griselda Loza-Diaz,2 Sanobar Hassan,1 Hamlet Suarez,3 Dario Geisinger,3 Pushpa Suriyaarachchi,1 Anita Sharma,1 Oddom Demontiero1,21Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, NSW, Australia; 2Ageing Bone Research Program, Division of Geriatric Medicine, Sydney Medical School Nepean, The University of Sydney, Penrith, NSW, Australia; 3British Hospital, CLAEH School of Medicine, Montevideo, UruguayAbstract: Poor balance is considered a challenging risk factor for falls in older adults. Therefore, innovative interventions for balance improvement in this population are greatly needed. The aim of this study was to evaluate the effect of a new virtual-reality system (the Balance Rehabilitation Unit [BRU] on balance, falls, and fear of falling in a population of community-dwelling older subjects with a known history of falls. In this study, 60 community-dwelling older subjects were recruited after being diagnosed with poor balance at the Falls and Fractures Clinic, Nepean Hospital (Penrith, NSW, Australia. Subjects were randomly assigned to either the BRU-training or control groups. Both groups received the usual falls prevention care. The BRU-training group attended balance training (two sessions/week for 6 weeks using an established protocol. Change in balance parameters was assessed in the BRU-training group at the end of their 6-week training program. Both groups were assessed 9 months after their initial assessment (month 0. Adherence to the BRU-training program was 97%. Balance parameters were significantly improved in the BRU-training group (P < 0.01. This effect was also associated with a significant reduction in falls and lower levels of fear of falling (P < 0.01. Some components of balance that were improved by BRU training showed a decline after 9 months post-training. In conclusion, BRU training is an effective and well-accepted intervention to improve balance

  4. New developments in prosthetic arm systems

    Directory of Open Access Journals (Sweden)

    Vujaklija I


    Full Text Available Ivan Vujaklija,1 Dario Farina,1 Oskar C Aszmann2 1Institute of Neurorehabilitation Systems, Bernstein Focus Neurotechnology Göttingen, University Medical Center Göttingen, Georg-August University, Göttingen, Germany; 2Christian Doppler Laboratory for Restoration of Extremity Function, Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria Abstract: Absence of an upper limb leads to severe impairments in everyday life, which can further influence the social and mental state. For these reasons, early developments in cosmetic and body-driven prostheses date some centuries ago, and they have been evolving ever since. Following the end of the Second World War, rapid developments in technology resulted in powered myoelectric hand prosthetics. In the years to come, these devices were common on the market, though they still suffered high user abandonment rates. The reasons for rejection were trifold – insufficient functionality of the hardware, fragile design, and cumbersome control. In the last decade, both academia and industry have reached major improvements concerning technical features of upper limb prosthetics and methods for their interfacing and control. Advanced robotic hands are offered by several vendors and research groups, with a variety of active and passive wrist options that can be articulated across several degrees of freedom. Nowadays, elbow joint designs include active solutions with different weight and power options. Control features are getting progressively more sophisticated, offering options for multiple sensor integration and multi-joint articulation. Latest developments in socket designs are capable of facilitating implantable and multiple surface electromyography sensors in both traditional and osseointegration-based systems. Novel surgical techniques in combination with modern, sophisticated hardware are enabling restoration of dexterous upper limb

  5. The Literary Criticism and Memoirs of Juan Ramón Jiménez

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    Allen W. Phillips


    Full Text Available Equally as demanding of others as he was of himself, Juan Ramón Jiménez conceived of literary criticism as a serious and exacting task. The critic and the poet, standing side by side, are devoted to complementary activities of mutual enrichment. However fragmentary and partial the critical opinions of Juan Ramón may be (also outspoken and polemical in nature, they are invaluable as a personal historical and aesthetic guide to about fifty or sixty years of Hispanic literary development (1900-1960. Not to take them into account is to fail to recognize a highly important aspect of his total artistic personality. These varied critical texts are a product of a first rate intelligence and the sensibility of a writer of consummate discrimination who was endowed not only with an excellent memory but also a very special talent for appreciating the authentic. Juan Ramón as a critic is quick to praise (San Juan, Bécquer, Dario, Unamuno and Machado and at the same time strong in his censure of certain contemporaries. Several recently collected volumes of miscellaneous critical materials have resolved the bibliographical muddle for the initial study of this fundamental aspect of the poet, but still particularly important are the expressionistic portraits of Españoles de tres mundos , longer tributes to Valle, Ortega and Villaespesa as well as the extensive lectures delivered in his latter years. Examination of these pages gives us an historical and creative overview of the period in which he lived and worked in addition to original considerations about the evolution of Hispanic poetry. Of course, one of the constant focal points of his literary criticism was the modernist epoch of his early days, a movement or attitude which he considered to be a modern twentieth century renaissance. Together with detailed study of these two areas of historical and aesthetic nature, in the ensuing pages some conclusions are pointed out as to the essence of poetry


    Directory of Open Access Journals (Sweden)

    Abner Ahnet Barrera Fernández


    Full Text Available Resumen Esta investigación ha caracterizado el proceso de enseñanza del Álgebra de Vectores implementada en Física desde la perspectiva de la Educación Matemática en la enseñanza de Educación Secundaria, sus características y dificultades en la enseñanza. El enfoque es cuantitativo con un diseño descriptivo. La muestra la conformaron 97 estudiantes del décimo grado y 4 docentes de las asignaturas de Física y Matemática, del Instituto Nacional Autónomo "Rubén Darío", del municipio de Nueva Guinea, a los cuales se les aplicaron test, encuesta, entrevista y guía de observación. En el análisis se ha utilizado el Sistema Estadístico para la Ciencias Sociales (SPSS, en los resultados de relevancia se puede mencionar el uso inadecuado de las propiedades de Álgebra de Vectores durante los procedimientos aplicados a definiciones y conceptos físicos por los estudiantes; asimismo, la búsqueda de los docentes para contrarrestar las debilidades en el aprendizaje del álgebra y la unificación de la herramienta Matemática de manera significativa, en el programa de estudio de Física de Educación Secundaria.   Summary This research has characterized the teaching process of linear algebra implemented in physics from the perspective of mathematics education in Secondary school education, their educational characteristics and difficulties. The approach is quantitative with a descriptive design. The sample consisted of 97 students from the tenth grade and 4 teachers that teach physics and mathematics at the National Autonomous Institute ¨Ruben Dario¨, of the municipality of Nueva Guinea to whom they applied, test, polls, interview, and observation guide. The statistical system for social sciences (SPSS was used in the analysis, amount the relevant results, we can mentioned misuse of the properties of linear algebra during procedures applied to definition and   concepts of physics by the students, likewise   the Search for teachers

  7. Dipeptidyl peptidase-4 inhibitors in type 2 diabetes therapy – focus on alogliptin

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    Capuano A


    Full Text Available Annalisa Capuano,1 Liberata Sportiello,1 Maria Ida Maiorino,2 Francesco Rossi,1 Dario Giugliano,2 Katherine Esposito3 1Department of Experimental Medicine, 2Department of Medical, Surgical, Neurological, Metabolic Sciences, and Geriatrics, 3Department of Clinical and Experimental Medicine and Surgery, Second University of Naples, Naples, Italy Abstract: Type 2 diabetes mellitus is a complex and progressive disease that is showing an apparently unstoppable increase worldwide. Although there is general agreement on the first-line use of metformin in most patients with type 2 diabetes, the ideal drug sequence after metformin failure is an area of increasing uncertainty. New treatment strategies target pancreatic islet dysfunction, in particular gut-derived incretin hormones. Inhibition of the enzyme dipeptidyl peptidase-4 (DPP-4 slows degradation of endogenous glucagon-like peptide-1 (GLP-1 and thereby enhances and prolongs the action of the endogenous incretin hormones. The five available DPP-4 inhibitors, also known as 'gliptins' (sitagliptin, vildagliptin, saxagliptin, linagliptin, alogliptin, are small molecules used orally with similar overall clinical efficacy and safety profiles in patients with type 2 diabetes. The main differences between the five gliptins on the market include: potency, target selectivity, oral bioavailability, long or short half-life, high or low binding to plasma proteins, metabolism, presence of active or inactive metabolites, excretion routes, dosage adjustment for renal and liver insufficiency, and potential drug–drug interactions. On average, treatment with gliptins is expected to produce a mean glycated hemoglobin (HbA1c decrease of 0.5%–0.8%, with about 40% of diabetic subjects at target for the HbA1c goal <7%. There are very few studies comparing DPP-4 inhibitors. Alogliptin as monotherapy or added to metformin, pioglitazone, glibenclamide, voglibose, or insulin therapy significantly improves glycemic control

  8. Combined isosorbide dinitrate and ibuprofen as a novel therapy for muscular dystrophies: evidence from Phase I studies in healthy volunteers

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    Cossu MV


    Full Text Available Maria Vittoria Cossu,1 Dario Cattaneo,1 Serena Fucile,1 Paolo Pellegrino,1 Sara Baldelli,1 Valeria Cozzi,1 Amedeo Capetti,2 Emilio Clementi1,3 1Unit of Clinical Pharmacology, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy; 2Unit of Infectious Diseases, University Hospital “Luigi Sacco”, Milan, Italy; 3Scientific Institute, IRCCS Eugenio Medea, Bosisio Parini, Lecco, Italy Abstract: We designed two Phase I studies that assessed healthy volunteers in order to evaluate the safety and to optimize the dosing of the combination of the drugs isosorbide dinitrate, a nitric oxide donor, and ibuprofen, a nonsteroidal antiinflammatory drug. We designed these studies with the aim of designing a Phase II trial to evaluate the drugs’ efficacy in patients affected by Duchenne muscular dystrophy. For the first trial, ISOFEN1, a single-dose, randomized-sequence, open-label, active control, three-treatment cross-over study, was aimed at comparing the pharmacokinetics of ibuprofen 200 mg and isosorbide dinitrate 20 mg when given alone and concomitantly. The pharmacokinetics of ibuprofen given alone versus ibuprofen given concomitantly with isosorbide dinitrate were similar, as documented by the lack of statistically significant differences in the main drug’s pharmacokinetic parameters (time to maximal concentration [Tmax], maximal concentration [Cmax], area under the curve [AUC]0–t, and AUC0–∞. Similarly, we found that the coadministration of ibuprofen did not significantly affect the pharmacokinetics of isosorbide dinitrate. No issues of safety were detected. The second trial, ISOFEN2, was a single-site, dose titration study that was designed to select the maximum tolerated dose for isosorbide dinitrate when coadministered with ibuprofen. Eighteen out of the 19 enrolled subjects tolerated the treatment well, and

  9. Pressure injuries in elderly with acute myocardial infarction

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    Komici K


    Full Text Available Klara Komici,1 Dino F Vitale,2 Dario Leosco,1 Angela Mancini,1 Graziamaria Corbi,3 Leonardo Bencivenga,1 Alessandro Mezzani,4 Bruno Trimarco,5 Carmine Morisco,5 Nicola Ferrara,1,2 Giuseppe Rengo1,2 1Division of Geriatrics, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy; 2Cardiac Rehabilitation Division, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN, Telese Terme, Italy; 3Department of Medicine and Health Sciences, University of Molise Campobasso, Campobasso, Italy; 4Cardiac Rehabilitation Division, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Veruno, Veruno, Italy; 5Division of Cardiology, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy Objectives: To assess pressure injury (PI incidence among patients hospitalized for acute myocardial infarction (AMI in an intensive coronary care unit (ICCU and to detect the impact of specific risk factors on the development of PI in this clinical setting.Patients and methods: Prospective cohort study in ICCU setting. Patients admitted for AMI: patients mean age 67.5±11.5 years (n=165. Norton Scale, Mini Nutritional Assessment (MNA, demographic, clinical and biochemical data collected at the time of ICCU admission have been tested in a logistic model to assess the odds ratios (ORs of PI risk development. The jackknifed area under the receiver operating characteristic curve (AUC and the decision curve analysis have been employed to assess the additive predictive value of a factor.Results: Twenty-seven (16.3% patients developed PIs. An increased PI risk was associated with advanced age (OR =2.5 every 10-year increase; 95% CI =1.1–5.7, while probability of PI development was reduced in patients with higher left ventricular ejection fraction (LVEF (OR =0.4 every 5% increase; 95% CI =0.24–0.66, MNA score (OR =0.65 every unit change; 95% CI =0.44–0.95 and Norton Scale score

  10. Does canopy mean N concentration explain differences in light use efficiency in 14 eddy-covariance sites? (United States)

    Peltoniemi, Mikko; Pulkkinen, Minna; Kolari, Pasi; Mäkelä, Annikki


    . Mean growing season VPD was the only climatic variable which correlated significantly with the largest actual LUE; none of them correlated with potential LUE. Inclusion of nitrogen in the Prelued-model structure did not improve the goodness of fit of the model. According to our results LUE correlates with mean canopy N concentration. The correlation of mean VPD with the largest actual LUE can also be explained with the model accounting for daily variation in climate, as was made with Prelued-model for the potential LUE. Further studies utilising seasonal values of canopy N are called upon. *Acknowledgements: Eero Nikinmaa, Pertti Hari, Timo Vesala, Tuomas Laurila, Fredrik Lagergren, Meelis Mölder, Anders Lindroth, Thomas Grünwald, Christian Bernhofer, Denis Loustau, Paul Berbigier, Beverly Law, Alison Dunn, Steve Wofsy, Torbjörn Johansson, Torben Christensen, Terry Callaghan, Hans Verbeeck, Remko Duursma, Leonardo Montagnani, Dario Papale, Andreas Ibrom, Ebba Dellwik, Kim Pilegaard, Kentaro Takagi, Eva van Gorsel, Heather Keith, Sonia Wharton, Matthias Falk, Kya Tha Paw U, Matt Schroeder, Jon Lloyd

  11. EDITORIAL: Focus on Dark Matter and Particle Physics (United States)

    Aprile, Elena; Profumo, Stefano


    Doetinchem, H Gast, T Kirn and S Schael Axion searches with helioscopes and astrophysical signatures for axion(-like) particles K Zioutas, M Tsagri, Y Semertzidis, T Papaevangelou, T Dafni and V Anastassopoulos The indirect search for dark matter with IceCube Francis Halzen and Dan Hooper DIRECT DARK MATTER SEARCHES:EXPERIMENTS Gaseous dark matter detectors G Sciolla and C J Martoff Search for dark matter with CRESST Rafael F Lang and Wolfgang Seidel DIRECT AND INDIRECT PARTICLE DARK MATTER SEARCHES:THEORY Dark matter annihilation around intermediate mass black holes: an update Gianfranco Bertone, Mattia Fornasa, Marco Taoso and Andrew R Zentner Update on the direct detection of dark matter in MSSM models with non-universal Higgs masses John Ellis, Keith A Olive and Pearl Sandick Dark stars: a new study of the first stars in the Universe Katherine Freese, Peter Bodenheimer, Paolo Gondolo and Douglas Spolyar Determining the mass of dark matter particles with direct detection experiments Chung-Lin Shan The detection of subsolar mass dark matter halos Savvas M Koushiappas Neutrino coherent scattering rates at direct dark matter detectors Louis E Strigari Gamma rays from dark matter annihilation in the central region of the Galaxy Pasquale Dario Serpico and Dan Hooper DARK MATTER MODELS The dark matter interpretation of the 511 keV line Céline Boehm Axions as dark matter particles Leanne D Duffy and Karl van Bibber Sterile neutrinos Alexander Kusenko Dark matter candidates Lars Bergström Minimal dark matter: model and results Marco Cirelli and Alessandro Strumia Shedding light on the dark sector with direct WIMP production Partha Konar, Kyoungchul Kong, Konstantin T Matchev and Maxim Perelstein Axinos as dark matter particles Laura Covi and Jihn E Kim

  12. Pareceristas da RBHCS no Triênio 2015-2017

    Directory of Open Access Journals (Sweden)

    Editores RBHCS


    Jonas Moreira Vargas (UFPel José Carlos da Silva Cardozo (FURG Karina Barra Gomes (UENF Lania Stefanoni Ferreira (Centro Universitário da FEI Leandro Karnal (Unicamp Leny Caselli Anzai (UFMT Luciana Mendes Gandelman (UFRRJ Luciana Rodrigues Penna (UFRGS Luciano Costa Gomes (UFRGS Luís Antonio Groppo (UNIFAL Luís Augusto Ebling Farinatti (UFSM Luisa Tombini Wittmann (UDESC Luiz Estevam de Oliveira Fernandes (UFOP Luiz Fernando Dias Duarte (Museu Nacional/ UFRJ Luiz Fernando Medeiros Rodrigues (UNISINOS Lyndon de Araújo Santos (UFMA Maíra Bonafé Sei (UEL Maísa Faleiros da Cunha (Unicamp Marcelo Henrique Nogueira Diana (IFC Marcelo Vianna (IFRS Marco Trentini (Universidad de Bologna - Itália Marcos Antonio Witt (UNISINOS Marcus Peixoto (UFRJ Maria Aparecida Bergamaschi (UFRGS Maria Cristina Bohn Martins (UNISINOS Maria de Nazaré Sarges (UFPA Maria Gabriela Silva Martins da Cunha Marinho (UFABC Mário Martins Viana Júnior (UFC Marlise Regina Meyrer (UPF Marta Regina Cioccari (UFRJ Mauro Dillmann (UFPEL Melina Piglia (Universidad Nacional de Mar del Plata - Argentina Micheli Verginia Ghiggi (UFMS Moacir de Freitas Junior (UFU Mônica da Silva Ribeiro (UFRRJ Mônica Ribeiro de Oliveira (UFJF Natália de Lacerda Gil (UFRGS Nathalia Monseff Junqueira (UFMS Nilson Gomes Vieira Filho (UFAM Patrice Schuch (UFRGS Patricia Dario El-Moor Hadjab (UNB Paulo Eduardo Teixeira (UNESP-Marília Paulo Henrique Martinez (UNESP Paulo Roberto Rodrigues Soares (UFRGS Pedro Eduardo Mesquita de Monteiro Marinho (Museu de Astronomia e Ciências Afins/UNIRIO Petrônio José Domingues (UFS Pompilio Locks Filho (UDESC Rauer Ribeiro Rodrigues (UFMS Rodrigo Stumpf González (UFRGS Roswithia Weber (FEEVALE Thiago Barcelos Soliva (UFRJ

  13. Rock Art Glossary: A Multilingual Dictionary, Expanded Second Edition (First Edition 2001. Edited by Robert G. Bednarik, Ahmed Achrati, Tang Huisheng, Alfred Muzzolini, George Dimitriadis, Dario Seglie, Fernando Coimbra, Yakov A. Sher and Mario Consens. Australian Rock Art Research Association, Inc., Melbourne, 2010; 274 Pages, in English, Arabic, Chinese, French, German, Greek, Italian, Portuguese, Russian and Spanish, with Translation Tables. Price $A 38.00, ISBN 978-0-646-53471-8

    Directory of Open Access Journals (Sweden)

    Shu-Kun Lin


    Full Text Available This is the first dictionary compiled specifically for rock art research. It follows the publication of an English rock art glossary in the journal Rock Art Research in November 2000. To be adopted by the International Federation of Rock Art Organisations (IFRAO, it has been translated by some of the world’s foremost scholars in the field into Arabic, Chinese, French, German, Greek, Italian, Portuguese, Spanish and Russian. In a discipline that has hitherto been without an agreed terminology, even communication within a single language has been difficult. The proliferation of idiosyncratic terminologies of often academically isolated researchers, many of which have been used by only one scholar, has not only retarded progress and the transference of knowledge, it has led to countless misunderstandings and even personal feuds. The purpose of this dictionary is to create a single terminological standard as well as a cross-lingual uniformity of usage. It focuses particularly on scientific aspects, technical applications and epistemological rigour. It does not set out to create a terminological straitjacket for the discipline, but a common standard of reference, particularly in areas that have in the past been susceptible to greatly differing interpretations. This dictionary comprises sections in ten languages, each listing the same terms alphabetically. It also contains a table interlinking all of these languages, listing all terms explained. This translation table is organised alphabetically according to the English terms. The volume is indispensable for scientific translators, rock art scholars, archaeologists and others concerned with aspects of pre-Historic rock art, and is also intended for the guidance of students and authors working in this field.

  14. PREFACE: Workshop Photograph and Program (United States)


    : Bonnie Fleming (Yale U.))18:30 Supernovae neutrino detection (20') Ines Gil-Botella (CIEMAT)18:50 Neutrino cross-section in Liquid Argon in the GeV range (15') Flavio Cavanna (U. of L'Aquila)19:05 Analysis of the ArgoNeuT neutrino data (15') Carl Bromberg (Michigan State U.)19:20 Neutrino event reconstruction (15') Gary Barker (U. of Warwick) Tuesday 30 March 2010Ways to improve the Liquid Argon Charge Imaging technology I (Chair: Christos Touramanis (U. of Liverpool))09:00 Liquid Argon LEM TPC (30') Filippo Resnati (ETH Zurich)09:30 Micromegas for charge readout of double phase liquid Argon large TPCs (20') Alain Delbart (Saclay)09:50 Development of Thick-GEMs for GEM-TPC Tracker (20') Fuminori Sakuma (RIKEN)10:10 Optical readout of the ionization (20') Neil Spooner (U. of Sheffield)10:30 Scintillation light readout (20') Kostas Mavrokoridis (U. of Liverpool)10:50-11:10 Coffee break Ways to improve the Liquid Argon Charge Imaging technology II (Chair: Alberto Marchionni (ETH Zurich))11:10 Development of cold electronics (30') Veljko Radeka (BNL)11:40 Development of a frontend ASIC and DAQ system Dario Autiero (IPN Lyon)12:00 CAEN digitizers (20') Carlo Tintori (CAEN)12:20 Recent results from Liquid Argon R&D activity (20') Masashi Tanaka (KEK)12:40 Results from the materials test stand and status of LAPD (20') Brian Rebel (FNAL)13:00 Purging and purification: 6 m3 @CERN (20') Alessandro Curioni (ETH Zurich)13:20-14:30 Lunch break14:30-20:00 Trip to J-PARC to visit T2K Beam Facility and Near Detector20:00-22:00 Workshop dinner at Okura Frontier Hotel Tsukuba Wednesday 31 March 2010Ways to improve the Liquid Argon Charge Imaging technology III (Chair: Takasumi Maruyama (KEK))09:00 ArgonTube and UV laser ionization (25') Biagio Rossi (U. of Bern)09:25 Detector magnetization (15') Andreas Badertscher (ETH Zurich)09:40 HV system (25') Sosuke Horikawa (ETH Zurich) Localization studies (Chair: Takuya Hasegawa (KEK))10:05 Okinoshima site study (20') Masakazu Yoshioka (KEK)10

  15. PREFACE: Loops 11: Non-Perturbative / Background Independent Quantum Gravity (United States)

    Mena Marugán, Guillermo A.; Barbero G, J. Fernando; Garay, Luis J.; Villaseñor, Eduardo J. S.; Olmedo, Javier


    only was it a showroom for the research currently being carried out by many groups throughout the world, but there was also a permanent look towards the future. During these days, the CSIC Campus witnessed many scientific conversations triggered by the interaction amongst the people and groups that participated in LOOPS'11 Madrid and which, in many cases, will crystallise into new results and advances in the field. The conference would not have been possible without the generous help of a number of national and international institutions. The organizers would like to acknowledge the financial support provided by the Spanish Ministry of Science and Innovation (Ministerio de Ciencia e Innovación), the Spanish Research Council, CSIC (Consejo Superior de Investigaciones Cientĺficas), The BBVA Foundation (Fundación BBVA), The CONSOLIDER-CPAN project, the Spanish Society for Gravitation and Relativity (SEGRE), The Universidad Carlos III of Madrid (UC3M), and the European Science Foundation (ESF). The ESF, through the Quantum Gravity and Quantum Geometry network, provided full support for a number of young participants that have contributed to these proceedings: Dario Benedetti (Albert Einstein Institute, Potsdam, Germany), Norbert Bodendorfer (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Mariam Bouhmadi López (CENTRA, Centro Multidisciplinar de Astrofĺsica, Lisbon), Timothy Budd (Institute for Theoretical Physics, Utrecht University, The Netherlands), Miguel Campiglia (Institute for Gravitation and the Cosmos, Penn State University, USA), Gianluca Delfino (School of Mathematical Sciences, University of Nottingham, UK), Maite Dupuis (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Michał Dziendzikowski (Institute of Theoretical Physics, Warsaw University, Poland), Muxin Han (Centre de Physique Théorique de Luminy, Marseille, France), Philipp Höhn (Institute for Theoretical Physics, Utrecht University, The

  16. PREFACE: International Conference on Computing in High Energy and Nuclear Physics (CHEP 2010) (United States)

    Lin, Simon C.; Shen, Stella; Neufeld, Niko; Gutsche, Oliver; Cattaneo, Marco; Fisk, Ian; Panzer-Steindel, Bernd; Di Meglio, Alberto; Lokajicek, Milos


    , as well as two banquets held at the Grand Hotel and Grand Formosa Regent in Taipei. The next CHEP conference will be held in New York, the United States on 21-25 May 2012. We would like to thank the National Science Council of Taiwan, the EU ACEOLE project, commercial sponsors, and the International Advisory Committee and the Programme Committee members for all their support and help. Special thanks to the Programme Committee members for their careful choice of conference contributions and enormous effort in reviewing and editing about 340 post conference proceedings papers. Simon C Lin CHEP 2010 Conference Chair and Proceedings Editor Taipei, Taiwan November 2011 Track Editors/ Programme Committee Chair Simon C Lin, Academia Sinica, Taiwan Online Computing Track Y H Chang, National Central University, Taiwan Harry Cheung, Fermilab, USA Niko Neufeld, CERN, Switzerland Event Processing Track Fabio Cossutti, INFN Trieste, Italy Oliver Gutsche, Fermilab, USA Ryosuke Itoh, KEK, Japan Software Engineering, Data Stores, and Databases Track Marco Cattaneo, CERN, Switzerland Gang Chen, Chinese Academy of Sciences, China Stefan Roiser, CERN, Switzerland Distributed Processing and Analysis Track Kai-Feng Chen, National Taiwan University, Taiwan Ulrik Egede, Imperial College London, UK Ian Fisk, Fermilab, USA Fons Rademakers, CERN, Switzerland Torre Wenaus, BNL, USA Computing Fabrics and Networking Technologies Track Harvey Newman, Caltech, USA Bernd Panzer-Steindel, CERN, Switzerland Antonio Wong, BNL, USA Ian Fisk, Fermilab, USA Niko Neufeld, CERN, Switzerland Grid and Cloud Middleware Track Alberto Di Meglio, CERN, Switzerland Markus Schulz, CERN, Switzerland Collaborative Tools Track Joao Correia Fernandes, CERN, Switzerland Philippe Galvez, Caltech, USA Milos Lokajicek, FZU Prague, Czech Republic International Advisory Committee Chair: Simon C. Lin , Academia Sinica, Taiwan Members: Mohammad Al-Turany , FAIR, Germany Sunanda Banerjee, Fermilab, USA Dario Barberis, CERN

  17. PREFACE: First Mediterranean Conference on Classical and Quantum Gravity (MCCQG 2009) (United States)

    Basilakos, Spyros; Cadoni, Mariano; Cavaglia, Marco; Christodoulakis, Theodosios; Vagenas, Elias C.


    Fisica, Universidade de Sao Paulo, Brasil) Antoniadis, Ignatios (CERN, Geneva, Switzerland) Arminjon, Mayeul (CNRS, Section of Theoretical Physics, France) Banados, Max (University of Oxford, UK) Basilakos, Spyros (RCAAM, Academy of Athens, Greece) Bastos, Catarina (IST, Departamento de Física, Portugal) Bertolami, Orfeu (IST, Departamento de Física, Portugal) Bevilaqua, Leandro Ibiapina (Instituto de Fisica, Universidade de Sao Paulo, Brazil) Bezerra De Mello, Eugenio (Dept. de Física, CCEN Universidade Federal da Paraíba, Brazil) Blake, Russ (Readify Pty Ltd, Australia) Bogdanos, Charalampos (LPT-Orsay, France) Burinskii, Alexander (Gravity Research Group NSI, Russian Academy of Sciences, Russia) Cadonati, Laura (University of Massachusetts, Amherst, USA) Cadoni, Mariano (Università di Cagliari, Italy) Capone, Monica (University of Turin, Italy) Cavaglià, Marco (University of Mississippi, USA) Chirco, Goffredo (SISSA-International School for Advanced Studies, Italy) Christodoulakis, Theodosios (University of Athens, Greece) Domingues Zarro, Carlos Augusto ((IST, Departamento de Física, Portugal) Durrer, Ruth (Université de Genève, Département de Physique Théorique, Switzerland) Fagnocchi, Serena (SISSA-International School for Advanced Studies, Italy) Finazzi, Stefano (SISSA-International School for Advanced Studies, Italy) Francia, Dario (University Paris 7 - APC, France) Ghosh, Subir (Indian Statistical Institute, India) Gomberoff, Andres (Universidad Catolica de Chile, Chile) Grumiller, Daniel (Institute for Theoretical Physics Vienna University of Technology, Austria) Herrera-Aguilar, Alfredo (IFM, Universidad Michoacana de San Nicolas de Hidalgo, Mexico) Hsu, Steve (University of Oregon, USA) Ichinose, Shoichi (University of Shizuoka, SFNS, Japan) Kiefer, Claus (Institute for Theoretical Physics, University of Cologne, Germany) Kokkotas, Kostas (Theoretical Astrophysics, Eberhard Karls University of Tuebingen, Germany) Kothawala, Dawood (IUCAA, Pune

  18. Sensing at the nanoscale (United States)

    Demming, Anna; Hierold, Christofer


    The merits of nanostructures in sensing may seem obvious, yet playing these attributes to their maximum advantage can be a work of genius. As fast as sensing technology is improving, expectations are growing, with demands for cheaper devices with higher sensitivities and an ever increasing range of functionalities and compatibilities. At the same time tough scientific challenges like low power operation, noise and low selectivity are keeping researchers busy. This special issue on sensing at the nanoscale with guest editor Christofer Hierold from ETH Zurich features some of the latest developments in sensing research pushing at the limits of current capabilities. Cheap and easy fabrication is a top priority. Among the most popular nanomaterials in sensing are ZnO nanowires and in this issue Dario Zappa and colleagues at Brescia University in Italy simplify an already cheap and efficient synthesis method, demonstrating ZnO nanowire fabrication directly onto silicon substrates [1]. Meanwhile Nicolae Barson and colleagues in Germany point out the advantages of flame spray pyrolysis fabrication in a topical review [2] and, maximizing on existing resources, researchers in Denmark and Taiwan report cantilever sensing using a US20 commercial DVD-ROM optical pickup unit as the readout source [3]. The sensor is designed to detect physiological concentrations of soluble urokinase plasminogen activator receptor, a protein associated with inflammation due to HIV, cancer and other infectious diseases. With their extreme properties carbon nanostructures feature prominently in the issue, including the demonstration of a versatile and flexible carbon nanotube strain sensor [4] and a graphene charge sensor with sensitivities of the order of 1.3 × 10-3 e Hz-1/2 [5]. The issue of patterning for sensing devices is also tackled by researchers in the US who demonstrate a novel approach for multicomponent pattering metal/metal oxide nanoparticles on graphene [6]. Changes in electrical

  19. PREFACE: Fourth Meeting on Constrained Dynamics and Quantum Gravity (United States)

    Cadoni, Mariano; Cavaglia, Marco; Nelson, Jeanette E.


    Cagliari, Italy) Roberto De Pietri (Università di Parma, Italy) Giuseppe De Risi (Università di Bari, Italy) Hans-Thomas Elze (Univ. Federal do Rio de Janeiro, Brasil) Alessandro Fabbri (Università di Bologna, Italy) Sergey Fadeev (VNIIMS, Moscow, Russia) Serena Fagnocchi (Università di Bologna, Italy) Sara Farese (Universidad de Valencia, Spain) Alessandra Feo (Università di Parma, Italy) Dario Francia (Università di Roma Tor Vergata, Italy) Francesco Fucito (Università di Roma Tor Vergata, Italy) Dmitri Fursaev (JINR, Dubna, Russia) Daniel Galehouse (University of Akron, Ohio, USA) Remo Garattini (Università di Bergamo, Italy) Florian Girelli (Perimeter Institute, Waterloo, Canada) Luca Griguolo (Università di Parma, Italy) Daniel Grumiller (Universität Leipzig, Germany) Shinichi Horata (Hayama Center of Advanced Research, Japan) Giorgio Immirzi (Università di Perugia, Italy) Roman Jackiw (MIT, Cambridge, USA) Matyas Karadi (DAMTP, University of Cambridge, UK) Mikhail Katanaev (Steklov Mathematical Institute, Moscow, Russia) Claus Kiefer (Universität Koln, Germany) John Klauder (University of Florida, Gainesville, USA) Pavel Klepac (Masaryk University, Brno, Czech Republic) Jen-Chi Lee (National Chiao-Tung University, Taiwan) Carlos Leiva (Universidad de Tarapacá, Arica, Chile) Stefano Liberati (SISSA/ISAS, Trieste, Italy) Jorma Louko (University of Nottingham, UK) Luca Lusanna (INFN, Sezione di Firenze, Italy) Roy Maartens (University of Portsmouth, UK) Fotini Markopoulou (Perimeter Institute, Waterloo, Canada) Annalisa Marzuoli (Università di Pavia, Italy) Evangelos Melas (QMW, University of London, UK) Maurizio Melis (Università di Cagliary, Italy) Vitaly Melnikov (VNIIMS, Moscow, Russia) Guillermo A. Mena Marugan (CSIC, Madrid, Spain) Pietro Menotti (Università di Pisa, Italy) Salvatore Mignemi (Università di Cagliari, Italy) Aleksandar Mikovic (Universidade Lusófona, Lisboa, Portugal) Leonardo Modesto (Université de la Mediterranée, Marseille