WorldWideScience

Sample records for anchorages

  1. Anchorage Areas

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — An anchorage area is a place where boats and ships can safely drop anchor. These areas are created in navigable waterways when ships and vessels require them for...

  2. TERRAIN, Anchorage, Alaska

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Anchorage AOI consists of seven areas. These areas were to be collected to the 'highest' accuracy requirement. Ground Control is collected throughout the AOI for...

  3. Onplant-supported orthodontic anchorage.

    Science.gov (United States)

    Armbruster, P C; Block, M S

    2001-03-01

    The use of onplant-supported orthodontic anchorage is still in its early stages. The concepts presented in this article have tried to stress the importance of anchorage control in orthodontic cases, some problems associated with traditional means to augment orthodontic anchorage, the rationale for developing a skeletal anchorage unit based on endosseous implant technology, and the effectiveness of the onplant as an anchorage unit. Cephalometric superimpositions are most likely the best method to determine the effectiveness of the onplant's contribution to anchorage control and have been included here to that end. Further research into its effectiveness may broaden the use of onplants in future orthodontic cases.

  4. New concept of physiologic anchorage control

    Directory of Open Access Journals (Sweden)

    Tian-Min Xu

    2015-01-01

    Full Text Available Molar anchorage loss in extraction case is believed due to the reaction of mechanical force applied to retract anterior teeth. While it may be close to truth in adult patients, it is certainly not true in adolescents. Studies on molar growth show upper molar move forward as mandible growing forward, probably through intercuspation force. Hence, for adolescents, molar anchorage loss shall consist of two parts. One is from retraction force - mechanical anchorage loss; another from biologic force - physiologic anchorage loss. Since physiologic anchorage loss is caused by the continuous biologic force, the strategy of physiologic anchorage control (PAC is different from the strategy of mechanical anchorage control. A new PAC method is introduced in this article that can reduce the headgear and temporary anchorage device used as sagittal anchorage dramatically in orthodontic clinic.

  5. [Different orthodontic anchorage systems. A critical examination].

    Science.gov (United States)

    Diedrich, P

    1993-08-01

    Every orthodontic measure requires a detailed analysis of the individual anchorage situation in order to absorb (stationary anchorage) or control (reciprocal anchorage) the reactive forces and moments. Basically, an anchorage is oriented to the quality of the biological anchorage of the teeth. This is influenced by a number of factors: size of root surface, attachment level, density and structure of alveolar bone, periodontal reactivity, muscular activity, occlusal forces, craniofacial morphology and the nature of the tooth movement resulting from the planned correction. The quality of the biological anchorage may be enhanced by selective modification of the position of the anchor teeth: cortical anchorage of the first molar (Ricketts), distal inclination of the molars (Tweed, Begg) and differential torque control (Burstone). In this context, undesired anchorage effects also need to be discussed, for example interaction between the teeth being corrected and compact bone structures (symphysis menti, floor of the maxillary sinus) or the loss of anchorage by periodontal hyalinization or excessive friction within the bracket slot. In addition, the anchorage situation of ankylosed teeth and endosseous implants, as well as the advantages and disadvantages of additional mechanical anchorage aids (head-gear, Nance holding arch, lingual arch) are discussed. On the basis of the complexity of the individual biological and biomechanical aspects, guidelines are derived with which to establish anchorage control matched to the specific situation.

  6. 33 CFR 401.50 - Anchorage areas.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Anchorage areas. 401.50 Section... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.50 Anchorage areas. Except in an... of the Seaway except in the following designated anchorage areas: (a) Point Fortier (Lake St....

  7. 77 FR 25587 - Anchorage Regulations; Wells, ME

    Science.gov (United States)

    2012-05-01

    ... SECURITY Coast Guard 33 CFR Part 110 RIN 1625-AA01 Anchorage Regulations; Wells, ME AGENCY: Coast Guard... three special anchorage areas in Wells Harbor, Wells, Maine, through a published final rule. The Marine.... Viewing Comments and Documents To view comments, as well as documents mentioned in this preamble as...

  8. 76 FR 52599 - Anchorage Regulations; Wells, ME

    Science.gov (United States)

    2011-08-23

    ... SECURITY Coast Guard 33 CFR Part 110 RIN 1625-AA01 Anchorage Regulations; Wells, ME AGENCY: Coast Guard... special anchorage areas in Wells Harbor, Wells, Maine. This proposed action is necessary to facilitate... in length. This action is intended to increase the safety of life and property in Wells...

  9. Paradigm shifts in orthodontic treatment with mini-implant anchorage

    Directory of Open Access Journals (Sweden)

    Johnny Joung-Lin Liaw

    2015-01-01

    Full Text Available After the applications of mini-implant anchorage, the envelope of orthodontic treatment was expanded and some treatment modes were changed because of more predictable tooth movement with empowered anchorage. The author tried to share his experience of TADs applications for clarifying the paradigm shifts of orthodontic treatment assisted with the mini-implant anchorage.

  10. 76 FR 76295 - Anchorage Regulations; Wells, ME

    Science.gov (United States)

    2011-12-07

    ... rule, call or email Mr. John J. Mauro, Waterways Management Branch Chief, First Coast Guard District; telephone (617) 223-8355, email John.J.Mauro@uscg.mil . If you have questions on viewing or submitting... placed well within the anchorage areas so that no portion of the hull or rigging will at any time...

  11. 77 FR 6010 - Anchorage Regulations; Newport, RI

    Science.gov (United States)

    2012-02-07

    ... of anchorage ``D'' at Newport, Rhode Island, to better accommodate increasing cruise ship visits to..., to better accommodate increasing cruise ship visits to Newport, and to improve navigation safety... ships simultaneously. Over the past several years, cruise ship visits to Newport, RI, have been...

  12. Comparison of temporary anchorage devices and transpalatal arch-mediated anchorage reinforcement during canine retraction

    Science.gov (United States)

    Kecik, Defne

    2016-01-01

    Objective: The purpose of this study was to compare the dental and skeletal effects of canine retraction using conventional anchorage reinforcement systems and comparing them with the usage of TADs. Materials and Methods: The sample consisted of 50 patients having Class I malocclusions with bimaxillary protrusion indicated for first premolar extraction, and allocated into two groups. The first group consisted of 25 patients with a mean age of 18,7 years (min:14, max:22 years, 16 girls and 9 boys) that TADs were applied as an anchorage mechanic between attached gingiva of upper second premolar and first molar teeth. The second group consisted of 25 patients with a mean age of 19,4 years (min:15, max:23 years, 14 girls and 11 boys) that conventional molar anchorage with Transpalatal arch (TPA) was applied for the anchorage mechanics against canine retraction. Results: The results showed that mean mesial movement and the tipping of the first molars in TAD group between T0 - T1 were insignificant (P > 0,05), however in the TPA group were significant (P0,05). Conclusion: Although TPA is a useful appliance, it doesn't provide an effective anchorage control on anteroposterior movement maxillary first molar teeth concerning first premolar extraction treatment. TADs are more convenient to provide absolute anchorage during maxillary canine retraction in contrast to transpalatal arch. PMID:28042267

  13. Orthodontic Anchorage Implants: State-of-the-art

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    the optimal positioning of the teeth following rehabilitation. Patients with need for inconsistent tooth movements, borderline surgical cases, can benefit from the use of the mini-implant and regeneration of alveolar process by tooth movement in edentulous molar regions and using mini-implants as anchorage......The limits of an orthodontic treatment are often set by the lack of suitable anchorage. The mini-implant is used where conventional anchorage cannot be applied and not as a replacement for conventional anchorage. In patients with lack of teeth and reduced periodontium, skeletal anchorage allows...

  14. Procedures adopted by orthodontists for space closure and anchorage control

    Directory of Open Access Journals (Sweden)

    André da Costa Monini

    2013-12-01

    Full Text Available OBJECTIVE: The aim of this study was to identify the procedures adopted by Brazilian orthodontists in the following situations: extraction space closure, anchorage control in case of necessary anchorage for group A and frequency of skeletal anchorage use, especially in the upper jaw. METHOD: A questionnaire was sent to the e-mail address of all dentists registered in the Brazilian Federal Council of Dentistry. RESULTS: The results showed that most Brazilian orthodontists usually perform extraction space closure by means of sliding mechanics. The use of palatal bar, inclusion of second molars in the archwire and space closure performed in two phases are the most used techniques for anchorage control in the upper jaw. The skeletal anchorage is referenced by 36.5% of specialists as a routine practice for the upper jaw anchorage. CONCLUSIONS: There is a wide variety of procedures adopted by Brazilian orthodontists for orthodontic space closure and anchorage control.

  15. Measuring the democratic anchorage of governance networks

    DEFF Research Database (Denmark)

    Fotel, Trine; Sørensen, Eva; Torfing, Jacob

    in what we shall call a model for the democratic anchorage of governance networks. As illustrated by our qualitative case study of a multi-level and cross-border governance network involved in the recent decision to build a bridge between Denmark and Germany, the democratic anchorage model helps to assess......There has been a growing debate about the democratic problems and potentials of governance networks among political scientists and public managers. While some claim that governance networks tend to undermine democracy, others argue that they have the potential to improve and strengthen democracy....... This debate is found wanting in two respects. First of all, there has been far too little discussion about what democracy means in relation to pluricentric governance networks. Second, the current debate builds on the assumption that it is possible to give a clear-cut answer to the question of the democratic...

  16. Is skeletal anchorage changing the limit of orthodontics?

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    The limits for orthodontic treatment are often set by the lack of suitable anchorage. The mini-implant is used where conventional anchorage cannot be applied; not as a replacement for conventional anchorage. In patients with lack of teeth and reduced periodontium, skeletal anchorage allows...... for the optimal positioning of the teeth before rehabilitation. Patients, with need for inconsistent tooth movements as displacement of all teeth in the same direction or asymmetric displacements, can be treated with the mini-implants. Borderline surgical cases can benefit from the use of mini......-implants. Regeneration of the alveolar process by tooth movement in edentulous molar regions using mini-implants as anchorage will improve the possibilities for reconstruction. The mini-implant serves thus as anchorage for a multiplicity of tooth movements; it can be inserted by the orthodontist, requires no drilling...

  17. 76 FR 78185 - Anchorage Regulations: Subpart A-Special Anchorage Regulations, Newport Bay Harbor, CA

    Science.gov (United States)

    2011-12-16

    ....gov and will include any personal information you have provided. Submitting Comments If you submit a... would be incorporated into area A-11 under revised Sec. 110.95(k). An image of the proposed anchorage... rule under Executive Order 13045, Protection of Children from Environmental Health Risks and...

  18. Orthodontic treatment with skeletal anchorage system

    Directory of Open Access Journals (Sweden)

    Arya Brahmanta

    2011-06-01

    Full Text Available Background: Correction of class I malocclusion with bimaxillary dental protrusion and unilateral free end right upper ridge in adult patient is one of difficult biomechanical case in orthodontics. Due to this case that needs proper anchorage for upper incisor retraction with missing teeth in the right posterior segment. Purpose: The aim of this study to find an effective therapy for correction of bimaxillary protrusion with unilateral free and ridge. Case: A female patient, 36 year old complaining for the difficulty of lip closure due to severe bimaxillary protrusion with incompetence lip. Case management: Firstly correction of the maxillary and mandibular incisor proclination were done by extraction of the mandibular first premolar, the maxillary second premolar on left side and finally placement of miniplates implant in the zygomatic process on right side as an absolut anchorage. Conclusion: Skeletal anchorage system (SAS can be considered as an effective therapy for corection of bimaxillary protrusion with unilateral free end ridge.Latar belakang: Koreksi dari maloklusi klas I dari penderita dewasa yang disertai protrusi bimaksiler dengan kehilangan gigi posterior pada regio kanan atas merupakan salah satu kasus sulit untuk dikerjakan terutama berhubungan dengan biomekanik pergerakan giginya dalam perawatan ortodonti. Tujuan: Tujuan dari penulisan artikel ini adalah untuk menemukan terapi yang efektif untuk perbaikan protrusi bimaksiler dan kehilangan gigi posterior pada satu sisi. Kasus: Seorang penderita wanita usia 35 tahun datang dengan keluhan utama kesulitan untuk menutup mulut oleh karena gigi rahang atas dan rahang bawahnya maju dan bibirnya tidak kompeten. Tatalaksana kasus: Koreksi pada gigi insisivus rahang atas dan insisivus rahang bawah yang protrusi dilakukan dengan melakukan pencabutan terlebih dahulu pada gigi premolar pertama dirahang bawah sisi kanan dan sisi kiri serta pencabutan pada gigi premolar kedua di rahang atas sisi

  19. Shear and anchorage behaviour of fire exposed hollow core slabs

    NARCIS (Netherlands)

    Fellinger, J.H.H.; Stark, J.; Walraven, J.C.

    2005-01-01

    The fire resistance of hollow core slabs is currently assessed considering flexural failure only. However, fire tests showed that shear or anchorage failure can also govern the load bearing behaviour. As the shear and anchorage capacity of these slabs rely on the tensile strength of the concrete, th

  20. 77 FR 22489 - Special Anchorage Regulations, Newport Bay Harbor, CA

    Science.gov (United States)

    2012-04-16

    ... Master Plan Subcommittee of the City of Newport Harbor Commission led an outreach campaign involving a... meetings, the City of Newport asked the Coast Guard to amend its anchorage regulations. The Coast Guard... incorporated into area A-11 under revised Sec. 110.95(k). An image of the anchorage areas is available in...

  1. 77 FR 54493 - Special Anchorage Area; Stockton Springs, ME

    Science.gov (United States)

    2012-09-05

    ... Number USCG-2012-0172] RIN 1625-AA01 Special Anchorage Area; Stockton Springs, ME AGENCY: Coast Guard... anchorage area in Stockton Springs, Maine. This proposed action is necessary to facilitate safe navigation.... This action is intended to increase the safety of life and property in Stockton Springs, improve...

  2. Mechanical anchorage of FRP tendons – A literature review

    DEFF Research Database (Denmark)

    Schmidt, Jacob W.; Bennitz, Anders; Täljsten, Björn

    2012-01-01

    anchorage systems for use with Aramid, Glass and Carbon FRP tendons have been proposed over the last two decades. Each system is usually tailored to a particular type of tendon. This paper presents a brief overview of bonded anchorage applications while the primary literature review discusses three methods...

  3. Anchorage of Main Reinforcement in Lightweight Aggregate Concrete Beams

    DEFF Research Database (Denmark)

    Larsen, Henning

    1999-01-01

    The paper deals with the anchorage of reinforcement bars at end supports in beam component made of lightweight aggregate concrete with open structure.......The paper deals with the anchorage of reinforcement bars at end supports in beam component made of lightweight aggregate concrete with open structure....

  4. Deformation tests and failure process analysis of an anchorage structure

    Institute of Scientific and Technical Information of China (English)

    Zhao Tongbin; Yin Yanchun; Tan Yunliang; Song Yimin

    2015-01-01

    In order to study the failure process of an anchorage structure and the evolution law of the body’s defor-mation field, anchor push-out tests were carried out based on digital speckle correlation methods (DSCM). The stress distribution of the anchorage interface was investigated using the particle flow numerical simulation method. The results indicate that there are three stages in the deformation and fail-ure process of an anchorage structure:elastic bonding stage, a de-bonding stage and a failure stage. The stress distribution in the interface controls the stability of the structure. In the elastic bonding stage, the shear stress peak point of the interface is close to the loading end, and the displacement field gradually develops into a ‘V’ shape. In the de-bonding stage, there is a shear stress plateau in the center of the anchorage section, and shear strain localization begins to form in the deformation field. In the failure stage, the bonding of the interface fails rapidly and the shear stress peak point moves to the anchorage free end. The anchorage structure moves integrally along the macro-crack. The de-bonding stage is a research focus in the deformation and failure process of an anchorage structure, and plays an important guiding role in roadway support design and prediction of the stability of the surrounding rock.

  5. Minor tooth movements using microimplant anchorage: case reports.

    Science.gov (United States)

    Sohn, Dong-Seok; Lee, Jung-Kwang; An, Kyung-Mi

    2008-03-01

    For the treatment of extruded or tipped molars, various conventional techniques have been used. But those methods may lead to undesirable movement of the anchorage units and lengthen treatment time because of limited tooth-borne anchorage potential. Introduction of microimplants as orthodontic anchorage has expanded treatment possibilities because of their advantages. Some advantages are a less complex surgical procedure, decrease in cost, immediate loading, and their ability to be placed in any area of the alveolar bone. This article will illustrate clinical experiences in patients who were treated with the intrusion of overerupted molars, the up-righting of tilted molars, and other clinical applications for minor tooth movements. Anchorage control was achieved with the surgical insertion of titanium microimplants for immediate loading in the alveolar bone. When needed, minimal fixed appliances were used and orthodontic treatment was completed without any other complications.

  6. Urban contaminants project: Fish and Hood Creeks, Anchorage, Alaska

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Urbanization has decreased water quality and adversely impacted biological communities in the lakes and streams of Anchorage, Alaska (Hock, 1981; Brabets, 1987;...

  7. 75 FR 3641 - Television Broadcasting Services; Anchorage, AK

    Science.gov (United States)

    2010-01-22

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Anchorage, AK AGENCY: Federal Communications... broadcasting. 0 For the reasons discussed in the preamble, the Federal Communications Commission amends 47...

  8. Prevalence of the use of anchorage miniscrews among French orthodontists.

    Science.gov (United States)

    Barthelemi, Stéphane; Beauval, Hélène

    2015-12-01

    Since always, anchorage has raised frequent problems for orthodontists. Since the early 2000s, the use of anchorage miniscrews has spread on a vast scale among practitioners. For the first time, a broad epidemiological survey (733 exploitable responses) has looked into the habits of French orthodontists regarding the use of anchorage miniscrews. The survey reveals that the majority of French practitioners have adopted miniscrews in their daily practice (66%), particularly among those using the lingual technique. However, the number of patients concerned still remains small for most practitioners (fewer than 10 patients for 65% of users). Seventy-four percent of users are satisfied with their experience with miniscrews although a majority uses them exclusively in adults (64%). The movements most sought by miniscrew users are mesialization/distalization and intrusion/extrusion. Among non-users, 60% have never placed an anchorage miniscrew but are thinking about doing so, whereas 20% of practitioners have used them but have since abandoned them. Finally, 20% of non-users have never used anchorage miniscrews and do not intend to do so.

  9. Clinical applications of orthodontic microimplant anchorage in craniofacial patients.

    Science.gov (United States)

    Vachiramon, Amornpong; Urata, Mark; Kyung, Hee Moon; Yamashita, Dennis-Duke; Yen, Stephen L-K

    2009-03-01

    Microimplant anchors, also known as temporary anchorage devices, mini- and micro-screws, have been used to enhance orthodontic anchorage for difficult tooth movements. Here, the authors describe how microimplants can be used to help treat craniofacial patients by supporting distraction osteogenesis procedures, maxillary protraction procedures, cleft segment expansion and stabilization, and tooth movement into narrow alveolar cleft sites. While most craniofacial patients are treated without microimplants, it would be worthwhile to identify which cases could benefit from microimplant anchorage. As an adjunct to orthodontic treatment, the microimplant offers a potential method for solving troublesome orthodontic and surgical problems such as guiding distraction procedures with orthodontics when primary teeth are exfoliating, addressing residual maxillary cants after vertical distraction osteogenesis of a ramus, stabilizing an edentulous premaxilla, and moving teeth into atrophic alveolar ridges. These cases are presented to open a dialogue on their possible uses in craniofacial patients.

  10. Shear and anchorage behaviour of fire exposed hollow core slabs

    NARCIS (Netherlands)

    Fellinger, J.

    2005-01-01

    The fire resistance of hollow core slabs is currently assessed considering flexural failure only. However, fire tests show that shear or anchorage failure can also govern the load bearing behaviour. This paper is based on the dissertation by the author1 and discusses existing and new fire tests. It

  11. Shear and Anchorage Behaviour of Fire Exposed Hollow Core Slabs

    NARCIS (Netherlands)

    Fellinger, J.H.H.

    2004-01-01

    Hollow core (HC) slabs are made of precast concrete with pretensioned strands. These slabs are popular as floor structures in offices and housing. At ambient conditions, the load bearing capacity can be dominated by four different failure modes, i.e. flexure, anchorage, shear compression and shear t

  12. Uvulo-glossopharyngeal dimensions in non-extraction, extraction with minimum anchorage, and extraction with maximum anchorage.

    Science.gov (United States)

    Germec-Cakan, Derya; Taner, Tulin; Akan, Seden

    2011-10-01

    The aim of this study was to investigate upper respiratory airway dimensions in non-extraction and extraction subjects treated with minimum or maximum anchorage. Lateral cephalograms of 39 Class I subjects were divided into three groups (each containing 11 females and 2 males) according to treatment procedure: group 1, 13 patients treated with extraction of four premolars and minimum anchorage; group 2, 13 cases treated non-extraction with air-rotor stripping (ARS); and group 3, 13 bimaxillary protrusion subjects treated with extraction of four premolars and maximum anchorage. The mean ages of the patients were 18.1 ± 3.7, 17.8 ± 2.4, and 15.5 ± 0.88 years, respectively. Tongue, soft palate, hyoid position, and upper airway measurements were made on pre- and post-treatment lateral cephalograms and the differences between the mean measurements were tested using Wilcoxon signed-ranks test. Superior and middle airway space increased significantly (P extraction treatment using maximum anchorage has a reducing effect on the middle and inferior airway dimensions.

  13. Reductive carboxylation supports redox homeostasis during anchorage-independent growth.

    Science.gov (United States)

    Jiang, Lei; Shestov, Alexander A; Swain, Pamela; Yang, Chendong; Parker, Seth J; Wang, Qiong A; Terada, Lance S; Adams, Nicholas D; McCabe, Michael T; Pietrak, Beth; Schmidt, Stan; Metallo, Christian M; Dranka, Brian P; Schwartz, Benjamin; DeBerardinis, Ralph J

    2016-04-14

    Cells receive growth and survival stimuli through their attachment to an extracellular matrix (ECM). Overcoming the addiction to ECM-induced signals is required for anchorage-independent growth, a property of most malignant cells. Detachment from ECM is associated with enhanced production of reactive oxygen species (ROS) owing to altered glucose metabolism. Here we identify an unconventional pathway that supports redox homeostasis and growth during adaptation to anchorage independence. We observed that detachment from monolayer culture and growth as anchorage-independent tumour spheroids was accompanied by changes in both glucose and glutamine metabolism. Specifically, oxidation of both nutrients was suppressed in spheroids, whereas reductive formation of citrate from glutamine was enhanced. Reductive glutamine metabolism was highly dependent on cytosolic isocitrate dehydrogenase-1 (IDH1), because the activity was suppressed in cells homozygous null for IDH1 or treated with an IDH1 inhibitor. This activity occurred in absence of hypoxia, a well-known inducer of reductive metabolism. Rather, IDH1 mitigated mitochondrial ROS in spheroids, and suppressing IDH1 reduced spheroid growth through a mechanism requiring mitochondrial ROS. Isotope tracing revealed that in spheroids, isocitrate/citrate produced reductively in the cytosol could enter the mitochondria and participate in oxidative metabolism, including oxidation by IDH2. This generates NADPH in the mitochondria, enabling cells to mitigate mitochondrial ROS and maximize growth. Neither IDH1 nor IDH2 was necessary for monolayer growth, but deleting either one enhanced mitochondrial ROS and reduced spheroid size, as did deletion of the mitochondrial citrate transporter protein. Together, the data indicate that adaptation to anchorage independence requires a fundamental change in citrate metabolism, initiated by IDH1-dependent reductive carboxylation and culminating in suppression of mitochondrial ROS.

  14. Synergetic material and structure optimization yields robust spider web anchorages.

    Science.gov (United States)

    Pugno, Nicola M; Cranford, Steven W; Buehler, Markus J

    2013-08-26

    Millions of years of evolution have adapted spider webs to achieve a range of properties, including the well-known capture of prey, with efficient use of materials. One feature that remains poorly understood is the attachment disc, a network of silk fibers that mechanically anchors a web to its environment. Experimental observations suggest that one possible attachment disc adheres to a substrate through multiple symmetrically branched structures composed of sub-micrometer scale silk fibers. Here, a theoretical model is used to explore the adaptation of the strength of attachment of such an anchorage, and complementary mesoscale simulations are applied to demonstrate a novel mechanism of synergetic material and structural optimization, such that the maximum anchorage strength can be achieved regardless of the initial anchor placement or material type. The optimal delamination (peeling) angle is facilitated by the inherent extensibility of silk, and is attained automatically during the process of delamination. This concept of self-optimizing peeling angle suggests that attachment discs do not require precise placement by the spider, irrespective of adhesion strength. Additional hierarchical branching of the anchorage increases efficiency, where both the delamination force and toughness modulus increase with a splitting of the cross-sectional area.

  15. Image guided placement of temporary anchorage devices for tooth movement

    Energy Technology Data Exchange (ETDEWEB)

    Bahl-Palomo, L.; Bissada, N. [Case Western Reserve Univ. School of Dental Medicine, Dept. of Periodontics, Cleveland, OH (United States); Palomo, J.M.; Hans, M.G. [Case Western Reserve Univ. School of Dental Medicine, Dept. of Orthodontics, Cleveland, OH (United States)

    2007-06-15

    The aim of this project is to develop an image guided protocol for placement of a temporary anchorage device without surgically reflecting a mucoperiosteal flap. Eighteen orthodontic cases were selected for skeletal anchorage from the department of orthodontics at Case University. CBCT images of the subjects were taken using the Hitachi CB MercuRay system set at 15 mA, 120 kVp. CBCT images evaluated the ideal location for TAD placement in three dimensions. Horizontal and vertical linear measurements were taken from fixed dental landmarks to clearly define the location for placement. Transverse slices were used to evaluate the thickness of the buccal plate. Using the transverse view, the angle of insertion was determined such that the maximum buccal plate surface area would contact the screw. TADs were placed in the optimum location, with the most appropriate angle of insertion using a closed approach and with minimal local anesthesia and without flap elevation. Results: All TADs were placed without anatomic encroachment and enabled fixed orthodontic anchorage. (orig.)

  16. External post-tensioning of cfrp tendons using integrated sleeve-wedge anchorage

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Bennitz, Anders; Goltermann, Per

    2012-01-01

    Strengthening of structures using external post-tension CFRP systems have proven to be anefficient method as such system increases the structural capacity and reduces cracks and deflection. Sufficient anchorage is of significant importance since the anchorage provides the connection between...... the post-tensioning system and the remaining structure. A special designed integrated sleeve-wedge anchorage has therefore been designed to improve the reliability of the mounting procedure, reduce the possible modes of failure and thus provide desired anchorage. The present research shows that adequate...

  17. Finite element simulation and testing of ISW CFRP anchorage

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Goltermann, Per; Hertz, Kristian Dahl

    2013-01-01

    Several Carbon Fibre Reinforced Polymers (CFRP) systems have been used successfully for strengthening of structures during the last decades. However, the fracture often occurs in the concrete adherent or in the adhesive interface when used for steel strengthening. As a consequence the CFRP...... is poorly utilized with a non ductile and brittle failure mode as the outcome. Mechanical anchorage can be used to utilize the full capacity of the CFRP materials but cannot yet challenge systems used for steel. Such systems can be used to transfer stresses from the CFRP material efficiently...

  18. Managing complex orthodontic problems: the use of implants for anchorage.

    Science.gov (United States)

    Kokich, V G

    1996-06-01

    Today implants are commonly used to replace missing teeth in partially edentulous adult orthodontic patients. Because these patients are missing teeth, orthodontic mechanics may be complicated or often impossible because of insufficient anchorage. In these situations, it may be feasible to use the implant initially as an orthodontic anchor to facilitate complex tooth movement and secondarily as an abutment for a crown or fixed prosthesis. This article will discuss the ramifications and requirements for using implants as anchors and abutments in adult orthodontic patients.

  19. Comparative photoelastic study of dental and skeletal anchorages in the canine retraction

    Directory of Open Access Journals (Sweden)

    Cristiane Aparecida de Assis Claro

    2014-01-01

    Full Text Available OBJECTIVE: To compare dental and skeletal anchorages in mandibular canine retraction by means of a stress distribution analysis. METHODS: A photoelastic model was produced from second molar to canine, without the first premolar, and mandibular canine retraction was simulated by a rubber band tied to two types of anchorage: dental anchorage, in the first molar attached to adjacent teeth, and skeletal anchorage with a hook simulating the mini-implant. The forces were applied 10 times and observed in a circular polariscope. The stresses located in the mandibular canine were recorded in 7 regions. The Mann-Whitney test was employed to compare the stress in each region and between both anchorage systems. The stresses in the mandibular canine periradicular regions were compared by the Kruskal-Wallis test. RESULTS: Stresses were similar in the cervical region and the middle third. In the apical third, the stresses associated with skeletal anchorage were higher than the stresses associated with dental anchorage. The results of the Kruskal-Wallis test showed that the highest stresses were identified in the cervical-distal, apical-distal, and apex regions with the use of dental anchorage, and in the apical-distal, apical-mesial, cervical-distal, and apex regions with the use of skeletal anchorage. CONCLUSIONS: The use of skeletal anchorage in canine retraction caused greater stress in the apical third than the use of dental anchorage, which indicates an intrusive component resulting from the direction of the force due to the position of the mini-implant and the bracket hook of the canine.

  20. 78 FR 9811 - Anchorages; Captain of the Port Puget Sound Zone, WA

    Science.gov (United States)

    2013-02-12

    ... area with a radius of 600 yards, having its center at 48 31'09'' N, 122 34'55'' W. (11) Cap Sante Tug and Barge General Anchorage. The Cap Sante Tug and Barge General Anchorage includes all waters... northeast tip of Cap Sante; then southeast to 48 30'53'' N, 122 35'28'' W; then west southwest to 48...

  1. 33 CFR 110.189a - Key West Harbor, Key West, Fla., naval explosives anchorage area.

    Science.gov (United States)

    2010-07-01

    ..., Key West, Fla., naval explosives anchorage area. (a) The anchorage ground. A circular area with its center at latitude 24°30′50.6″, longitude 81°50′31.6″ with a radius of 300 yards, for use for ammunition exceeding the prescribed limits for pier-side handling. (b) The regulations. (1) When occupied by a...

  2. Flexural Strengthening of RC Slabs with Prestressed CFRP Strips Using Different Anchorage Systems

    Directory of Open Access Journals (Sweden)

    José Sena-Cruz

    2015-10-01

    Full Text Available Externally Bonded Reinforcement (EBR technique has been widely used for flexural strengthening of concrete structures by using carbon fiber-reinforced polymers (CFRP. EBR technique offers several structural advantages when the CFRP material is prestressed. This paper presents an experimental and numerical study on reinforced (RC slabs strengthened in flexure with prestressed CFRP strips as a structural strengthening system. The strips are applied as an externally bonded reinforcement (EBR and anchored with either a mechanical or a gradient anchorage. The former foresees metallic anchorage plates fixed to the concrete substrate, while the latter is based on an accelerated epoxy resin curing followed by a segment-wise prestress force decrease at the strip ends. Both anchorage systems, in combination with different CFRP strip geometries, were subjected to static loading tests. It could be demonstrated that the composite strip’s performance is better exploited when prestressing is used, with slightly higher overall load carrying capacities for mechanical anchorages than for the gradient anchorage. The performed investigations by means of a cross-section analysis supported the experimental observation that in case a mechanical anchorage is used, progressive strip debonding changes the fully bonded configuration to an unbonded end-anchored system. The inclusion of defined debonding criteria for both the anchorage zones and free length between the anchorage regions allowed to precisely capture the ultimate loading forces.

  3. 49 CFR 393.93 - Seats, seat belt assemblies, and seat belt assembly anchorages.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Seats, seat belt assemblies, and seat belt... § 393.93 Seats, seat belt assemblies, and seat belt assembly anchorages. (a) Buses—(1) Buses... the driver's seat and seat belt assembly anchorages that conform to the location and...

  4. Summary of Quaternary geology of the Municipality of Anchorage, Alaska

    Science.gov (United States)

    Schmoll, H.R.; Yehle, L.A.; Updike, R.G.

    1999-01-01

    Quaternary geology of the Upper Cook Inlet region is dominated by deposits of glacier retreats that followed repeated advances from both adjacent and more distant mountains. At several levels high on the mountains, there are remnant glacial deposits and other features of middle or older Pleistocene age. Late Pleistocene lateral moraines along the Chugach Mountain front represent successively younger positions of ice retreat from the last glacial maximum. As the trunk glacier retreated northeastward up the Anchorage lowland, Cook Inlet transgressed the area, depositing the Bootlegger Cove Formation and Tudor Road deposits. The glacier then readvanced to form the latest Pleistocene Elmendorf Moraine, a prominent feature that trends across the Anchorage lowland. Extensive alluvium was deposited both concurrently and somewhat later as Cook Inlet regressed. Mountain valleys contain (1) locally preserved moraines possibly of early Holocene age; (2) poorly preserved moraine remnants of older late Holocene age; and (3) well-preserved moraines formed mainly during the Little Ice Age. Glaciers still occupy large parts of the mountains, the upper ends of some mountain valleys, and small cirques. Holocene landslide deposits, including those formed during the great Alaska earthquake of 1964, occur throughout the area, especially along bluffs containing the Bootlegger Cove Formation.

  5. Treatment of a Class II deepbite with microimplant anchorage.

    Science.gov (United States)

    Park, Hyo-Sang; Kim, Ji-Yeun; Kwon, Tae-Geon

    2011-03-01

    The goal of this report was to illustrate new treatment mechanics for using microimplants for the treatment of a Class II Division 2 deepbite malocclusion. A 29-year-old woman with a deepbite was treated with the aid of microimplant anchorage. Microimplants placed between the maxillary second premolars and first molars were used as anchorage to apply a distal force to the anterior teeth to correct the Class II canine and molar relationships. A distal force was applied to long hooks that were crimped between the lateral incisors and the canines. By applying a backward force to the long hooks, the maxillary anterior teeth experienced palatal root movement with no change in the vertical and anteroposterior positions of the incisal edges. The distal extrusive movement of the maxillary second molars achieved by disengaging the second molars from the archwire during distal force application and an anterior bite-block bonded on the lingual surface of the maxillary central incisors produced the increase in vertical dimension. The distal force to the long extended hooks from the microimplants was possibly good mechanics for obtaining the palatal root movement and correcting the Class II canine and molar relationships. The anterior bite-block and disengagement of the maxillary second molars during distal force application were effective for increasing the vertical dimension.

  6. Mini-Implants in the Anchorage Armamentarium: New Paradigms in the Orthodontics

    Science.gov (United States)

    Yamaguchi, Masaru; Inami, Toshihiro; Ito, Ko; Kasai, Kazutaka; Tanimoto, Yasuhiro

    2012-01-01

    Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD). These devices are small, are implanted with a relatively simple surgical procedure, and increase the potential for better orthodontic results. Therefore, miniscrews not only free orthodontists from anchorage-demanding cases, but they also enable clinicians to have good control over tooth movement in 3 dimensions. The miniplate type also produces significant improvements in treatment outcomes and has widened the spectrum of orthodontics. The purpose of this paper is to update clinicians on the current concepts and versatile uses and clinical applications of skeletal anchorage in orthodontics. PMID:22719763

  7. Evaluation of dredged material proposed for ocean disposal from Gravesend Bay Anchorage, New York

    Energy Technology Data Exchange (ETDEWEB)

    Barrows, E.S.; Gruendell, B.D. [Battelle/Marine Sciences Lab., Sequim, WA (United States)

    1996-09-01

    The Gravesend Bay Anchorage was one of seven waterways that the US Army Corps of Engineers-New York District (USACE-NYD) requested the Battelle Marine Sciences Laboratory (MSL) to sample and evaluate for dredging and disposal in February 1994. Sediment samples were submitted for physical and chemical analyses to provide baseline sediment chemistry data on the Gravesend Bay Anchorage. Individual sediment core samples collected at the Gravesend Bay Anchorage were analyzed for grain size, moisture content, and total organic carbon (TOC). Two samples, one of composited sediment cores representing the southeast corner of the anchorage (COMP GR), and one sediment core representing the northeast corner of the anchorage (Station GR-1 0), were analyzed for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congeners, polynuclear aromatic hydrocarbons (PAH), and 1,4-dichlorobenzene.

  8. Mini-Implants in the Anchorage Armamentarium: New Paradigms in the Orthodontics

    Directory of Open Access Journals (Sweden)

    Masaru Yamaguchi

    2012-01-01

    Full Text Available Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD. These devices are small, are implanted with a relatively simple surgical procedure, and increase the potential for better orthodontic results. Therefore, miniscrews not only free orthodontists from anchorage-demanding cases, but they also enable clinicians to have good control over tooth movement in 3 dimensions. The miniplate type also produces significant improvements in treatment outcomes and has widened the spectrum of orthodontics. The purpose of this paper is to update clinicians on the current concepts and versatile uses and clinical applications of skeletal anchorage in orthodontics.

  9. 1964 Great Alaska Earthquake: a photographic tour of Anchorage, Alaska

    Science.gov (United States)

    Thoms, Evan E.; Haeussler, Peter J.; Anderson, Rebecca D.; McGimsey, Robert G.

    2014-01-01

    On March 27, 1964, at 5:36 p.m., a magnitude 9.2 earthquake, the largest recorded earthquake in U.S. history, struck southcentral Alaska (fig. 1). The Great Alaska Earthquake (also known as the Good Friday Earthquake) occurred at a pivotal time in the history of earth science, and helped lead to the acceptance of plate tectonic theory (Cox, 1973; Brocher and others, 2014). All large subduction zone earthquakes are understood through insights learned from the 1964 event, and observations and interpretations of the earthquake have influenced the design of infrastructure and seismic monitoring systems now in place. The earthquake caused extensive damage across the State, and triggered local tsunamis that devastated the Alaskan towns of Whittier, Valdez, and Seward. In Anchorage, the main cause of damage was ground shaking, which lasted approximately 4.5 minutes. Many buildings could not withstand this motion and were damaged or collapsed even though their foundations remained intact. More significantly, ground shaking triggered a number of landslides along coastal and drainage valley bluffs underlain by the Bootlegger Cove Formation, a composite of facies containing variably mixed gravel, sand, silt, and clay which were deposited over much of upper Cook Inlet during the Late Pleistocene (Ulery and others, 1983). Cyclic (or strain) softening of the more sensitive clay facies caused overlying blocks of soil to slide sideways along surfaces dipping by only a few degrees. This guide is the document version of an interactive web map that was created as part of the commemoration events for the 50th anniversary of the 1964 Great Alaska Earthquake. It is accessible at the U.S. Geological Survey (USGS) Alaska Science Center website: http://alaska.usgs.gov/announcements/news/1964Earthquake/. The website features a map display with suggested tour stops in Anchorage, historical photographs taken shortly after the earthquake, repeat photography of selected sites, scanned documents

  10. FRP tendon anchorage in post-tensioned concrete structures

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Täljsten, Björn; Bennitz, Anders

    2008-01-01

    Strengthening of building structures by the use of various external post-tensioning steel tendon systems, is known to be a very efficient method. However, FRP as material in external post-tensioning projects has been investigated during the last decade. The advantages for this material are the high...... transfer points. The demand for high capacity anchorage tendons is fulfilled for steel tendons, but no competitive mechanical anchor has yet been developed for FRP tendon. A new small, reliable and more user friendly anchor has to be developed, before FRP tendons can be utilized with all of its capacity....... Thus, several attempts of developing a mechanical FRP anchor have been made worldwide with promising results. Some of these attempts are presented in this paper together with an insight into a present research collaboration project at the Technical University of Denmark, Luleå University of Technology...

  11. Numerical Analysis of Quality Inspection of Anchorage System

    Institute of Scientific and Technical Information of China (English)

    ZHANGYongxing; XUMing

    2002-01-01

    Sonoprobe method has been applied in non-destructive inspection of anchorage project.The fundament is that dynamic transient excitation causes the elastic vibration of an anchor bar,and flaws can be estimated or deduced by determining transient response of the anchor bar.FEA numeric solution of hyperbolic equation indicates that deductions must comply with acoustic parameters such as velocity of sound,vibration range,wave shape etc when inspecting interior flaws in the grout of an anchor bar,Based on wavelet packet analysis,the energy eigenvector is a flaw vector,which could be regarded as the basis in the nondestructive inspection of anchors,As a non-linear dynamical system,artifical neural networks dealing with quality insection of gray system have been proved efficient.

  12. Comparison of Anchorage Pattern under Two Types of Orthodontic Mini- Implant Loading During Retraction in Type A Anchorage Cases

    Science.gov (United States)

    Khan, B. Imran; Mandava, Prasad; Reddy, G. Vivek; Nettam, Venkatesh; Bhavikati, Venkat Naidu

    2016-01-01

    Introduction The orthodontic mini-screws are the mainstay of direct skeletal anchorage which requires minimal compliance and provides maximal anchorage control. However, the timing of initiation of orthodontic loading of these mini-screws is not clearly established in the available studies. Aim The purpose of this study was to determine the reciprocal effects on mini-screw implant with immediate loading in comparison to that of delayed loading during retraction. Materials and Methods The prospective clinical study included a sample of 25 orthodontic patients in the age range of 18-25 years. All the cases were of bi-maxillary proclination with Type-A anchorage demands. All the first premolars were indicated for extraction. A split mouth technique for each patient was utilized by loading mini-implant immediately after its placement on one side and the opposite side implant was loaded after a time lag of two weeks post-insertion. Retraction force of 150g was applied for three months on each side. The displacement of the head and tail of the implant, molar anterior tooth retraction was measured on Orthopantomograph (OPG) taken at T1 (initial) and T2 (after three months). A grid method with each 1mm magnified to 500 pixels was superimposed on OPG and the relative displacements were evaluated. Student’s unpaired ‘t’ test was used for comparison between left and right side and paired ‘t’ test for the parameters on the same side. The p-value equal to or less than 0.05 was taken as statistically significant. Results The mean displacement of head of the implant on the immediate loading is 0.57mm where as the tail exhibited 0.75 mm. The head and tail of the implant on the delayed loading displaced by 0.35mm and 0.38mm respectively, on an average when data was analysed. Significant difference between the two types of loading was noted. Conclusion Delayed loading is beneficial as compared to immediate loading during extraction space closure. PMID:27891469

  13. Exterior beam-column joint study with non-conventional reinforcement detailing using mechanical anchorage under reversal loading

    Indian Academy of Sciences (India)

    S Rajagopal; S Prabavathy

    2014-10-01

    Reinforced concrete structures beam-column joints are the most critical regions in seismic prone areas. Proper reinforcement anchorage is essential to enhance the performance of the joints. An attempt has been made to appraise the performance of the anchorages and joints. The anchorages are detailed as per ACI-352 (mechanical anchorages), ACI-318 (conventional bent hooks) and IS-456 (conventional full anchorage). The joints are detailed without confinement in group-I and with additional X-cross bar in group-II. To assess the seismic performance, the specimens are assembled into two groups of three specimens each and were tested under reversal loading, The specimen with T-type mechanical anchorage (Headed bar) and T-type mechanical anchorage combination with X-cross bar exhibited significant improvement in seismic performance: load-displacement capacity, displacement ductility, stiffness degradation, controlled crack capacity in the joint shear panel and also reduced congestion of reinforcement in joint core.

  14. Numerical Simulation and Experimental Validation of an Integrated Sleeve-Wedge Anchorage for CFRP Rods

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Smith, Scott T.; Täljsten, Björn;

    2011-01-01

    . Recently, an integrated sleeve-wedge anchorage has been successfully developed specifically for CFRP rods. This paper in turn presents a numerical simulation of the newly developed anchorage using ABAQUS. The three-dimensional finite element (FE) model, which considers material non-linearity, uses...... hexagonal elements for the barrel and CFRP rod and tetrahedral elements for the integrated sleeve-wedge. The simulated barrel surface strains are shown to compare well with optically measured strains, however, the numerical results are shown to be sensitive to the mechanical properties of the anchorage...

  15. Urban contaminants project: Data for sediment, fish and eggs collected from Chester Creek, Anchorage, Alaska 1991

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Urbanization has degraded the water quality and adversely impacted biological communities in the lakes and streams of Anchorage. Pollution from point and nonpoint...

  16. Transfer and anchorage bond behaviour in self-compacting concrete

    Directory of Open Access Journals (Sweden)

    Rigueira-Víctor, J. W.

    2006-12-01

    Full Text Available Self-compacting concretes (SCC provide solutions to the problems facing precast concrete construction, enhancing competitiveness, reducing turnaround times and improving final product quality. SCC is fast becoming a key product for the future development of the precast pre-stressed concrete industry.The present paper compares the bond performance of SCC and traditional concrete (TC. The bond performance results confirm the viability of SCC in precast pre-stressed concrete manufacture, despite a slightly higher loss of pre-stressing force and slightly greater anchorage lengths in SCC with a low water/cement ratio. No differences in transfer or anchorage length were detected,however, when high strength TC and SCC were compared. The ECADA test method proved to be well suited to detecting the differences between the concretes analyzed.El desarrollo de los hormigones autocompactantes (SCCofrece muchas posibilidades a las construcciones con hormigón prefabricado, aumentando su competitividad, reduciéndolos plazos de fabricación y ofreciendo mejoras en la calidad del producto final. El SCC se está convirtiendo en un producto clave para el futuro desarrollo de la industria de prefabricados de hormigón pretensado.En este estudio se compara el comportamiento adherente de los SCC con el de los hormigones tradicionales (TC actuales. Los resultados obtenidos confirman la viabilidad del uso de los SCC para la fabricación de elementos prefabricados con hormigón pretensado, en lo relativo a su comportamiento adherente, aunque con la necesidad de considerar unas pérdidas de pretensado ligeramente mayores. Asimismo,debe esperarse un ligero aumento de las longitudes de anclaje cuando se trabaje con SCC de baja relación agua/cemento. Sin embargo, no se han detectado diferencias de comportamiento entre ambos tipos de hormigón cuando la resistencia a compresión es alta en lo relativo a las longitudes de transmisión y anclaje. El método de ensayo ECADA

  17. Mechanical properties and failure characteristics of fractured sandstone with grouting and anchorage

    Institute of Scientific and Technical Information of China (English)

    Zong Yijiang; Han Lijun; Qu Tao; Yang Shengqi

    2014-01-01

    Based on uniaxial compression experimental results on fractured sandstone with grouting and anchorage, we studied the strength and deformation properties, the failure model, crack formation and evolution laws of fractured sandstone under different conditions of anchorage. The experimental results show that the strength and elastic modulus of fractured sandstone with different fracture angles are sig-nificantly lower than those of intact sandstone. Compared with the fractured samples without anchorage, the peak strength, residual strength, peak and ultimate axial strain of fractured sandstone under different anchorage increase by 64.5-320.0%, 62.8-493.0%, and 31.6-181.4%, respectively. The number of bolts and degree of pre-stress has certain effects on the peak strength and failure model of fractured sandstone. The peak strength of fractured sandstone under different anchorage increases to some extent, and the failure model of fractured sandstone also transforms from tensile failure to tensile-shear mixed failure with the number of bolts. The pre-stress can restrain the formation and evolution process of tensile cracks, delay the failure process of fractured sandstone under anchorage and impel the transformation of failure model from brittle failure to plastic failure.

  18. Maps showing seismic landslide hazards in Anchorage, Alaska

    Science.gov (United States)

    Jibson, Randall W.

    2014-01-01

    The devastating landslides that accompanied the great 1964 Alaska earthquake showed that seismically triggered landslides are one of the greatest geologic hazards in Anchorage. Maps quantifying seismic landslide hazards are therefore important for planning, zoning, and emergency-response preparation. The accompanying maps portray seismic landslide hazards for the following conditions: (1) deep, translational landslides, which occur only during great subduction-zone earthquakes that have return periods of =300-900 yr; (2) shallow landslides for a peak ground acceleration (PGA) of 0.69 g, which has a return period of 2,475 yr, or a 2 percent probability of exceedance in 50 yr; and (3) shallow landslides for a PGA of 0.43 g, which has a return period of 475 yr, or a 10 percent probability of exceedance in 50 yr. Deep, translational landslide hazards were delineated based on previous studies of such landslides, with some modifications based on field observations of locations of deep landslides. Shallow-landslide hazards were delineated using a Newmark-type displacement analysis for the two probabilistic ground motions modeled.

  19. Experimental study and stress analysis of rock bolt anchorage performance

    Directory of Open Access Journals (Sweden)

    Yu Chen

    2014-10-01

    Full Text Available A new method was developed to apply pull-and-shear loads to the bolt specimen in order to evaluate the anchorage performance of the rebar bolt and the D-Bolt. In the tests, five displacing angles (0°, 20°, 40°, 60°, and 90°, two joint gaps (0 mm and 30 mm, and three kinds of host rock materials (weak concrete, strong concrete, and concrete-granite were considered, and stress–strain measurements were conducted. Results show that the ultimate loads of both the D-Bolt and the rebar bolt remained constant with any displacing angles. The ultimate displacement of the D-Bolt changed from 140 mm at the 0° displacing angle (pure pull to approximately 70 mm at a displacing angle greater than 40°. The displacement capacity of the D-Bolt is approximately 3.5 times that of the rebar bolt under pure pull and 50% higher than that of the rebar bolt under pure shear. The compressive stress exists at 50 mm from the bolt head, and the maximum bending moment value rises with the increasing displacing angle. The rebar bolt mobilises greater applied load than the D-Bolt when subjected to the maximum bending. The yielding length (at 0° of the D-Bolt is longer than that of the rebar bolt. The displacement capacity of the bolts increased with the joint gap. The bolt subjected to joint gap effect yields more quickly with greater bending moment and smaller applied load. The displacement capacities of the D-Bolt and the rebar bolt are greater in the weak host rock than that in the hard host rock. In pure shear condition, the ultimate load of the bolts slightly decreases in the hard rock. The yielding speed in the hard rock is higher than that in the weak rock.

  20. Thick-Walled Cylinder Theory Applied on a Conical Wedge Anchorage

    DEFF Research Database (Denmark)

    Bennitz, Anders; Grip, Niklas; Schmidt, Jacob Wittrup

    2011-01-01

    Conical wedge anchorages are frequently used to anchor steel tendons in prestressing applications within the construction industry. To replace the steel tendons with non-corrosive and low weight FRPs (Fiber Reinforced Polymers), the different mechanical interactions between the steel and FRPs call...... for further development of the anchorage.In this paper, we derive and examine an analytical model for the internal stresses and strains within the anchorage for a prescribed presetting distance. This model is derived from the theory of thick walled cylinders under the assumptions regarding plane stress...... and axial symmetry. We simplify the resulting system of ten nonlinear equations and derive a method for solving them numerically. A comparison of plotted results for three different angles on the wedge’s outer surface and six different presetting distances follows.These results are also compared to both axi...

  1. Bio-cultural anchorage of the prickly pear cactus in Tlalnepantla (Morelos), Mexico

    OpenAIRE

    Torres-Salcido, Gerardo; Ramos-Chávez, Alejandro; Urreta-Fernández, Álvaro

    2016-01-01

    The prickly pear cactus is a source of food with strong bio-cultural anchorage in Mexico. This is due to at least three factors: 1) the nature and heritage of cacti; 2) cultural heritage; and 3) the socio-cultural relationships with historical and symbolic roots that have facilitated knowledge of how to cultivate it and how to use it. The aim of this article is to put factors of territorial anchorage and its historical transformation in context by examining the case of the municipality of Tla...

  2. 77 FR 35104 - Notice of Request To Release Airport Property at Merrill Field Airport, Anchorage, AK

    Science.gov (United States)

    2012-06-12

    ... Anchorage, Alaska, on June 6, 2012. Byron K. Huffman, Division Manager, FAA, Alaskan Region. BILLING CODE... lands in accordance with Title 23, Part 710.509 of the Code of Federal Regulations and Section 6.13 of...-26, ARD. In accordance with Title 49 of the United States Code (U.S.C.), Section 47107(h)(2),...

  3. Experimental evidence of pharmacological management of anchorage in Orthodontics: A systematic review

    Science.gov (United States)

    Fernández-González, Felipe José; Cañigral, Aránzazu; Balbontín-Ayala, Felipe; Gonzalo-Orden, José Manuel; de Carlos, Felix; Cobo, Teresa; Fernández-Vázquez, Jose Pedro; Sánchez-Lasheras, Fernando; Vega, José Antonio

    2015-01-01

    Introduction: Orthodontic anchorage is one of the most challenging aspects of Orthodontics. Preventing undesired movement of teeth could result in safer and less complicated orthodontic treatment. Recently, several reviews have been published about the effects of different molecules on bone physiology and the clinical side effects in Orthodontics. However, the effects of local application of these substances on the rate of orthodontic tooth movement have not been assessed. Objectives: The aim of this research was to analyze the scientific evidence published in the literature about the effects of different molecules on orthodontic anchorage. Methods: The literature was systematically reviewed using PubMed/Medline, Scopus and Cochrane databases from 2000 up to July 31st, 2014. Articles were independently selected by two different researchers based on previously established inclusion and exclusion criteria, with a concordance Kappa index of 0.86. The methodological quality of the reviewed papers was performed. Results: Search strategy identified 270 articles. Twenty-five of them were selected after application of inclusion/exclusion criteria, and only 11 qualified for final analysis. Molecules involved in orthodontic anchorage were divided into three main groups: osteoprotegerin (OPG), bisphosphonates (BPs) and other molecules (OMs). Conclusions: Different drugs are able to alter the bone remodeling cycle, influencing osteoclast function and, therefore, tooth movement. Thus, they could be used in order to provide maximal anchorage while preventing undesired movements. OPG was found the most effective molecule in blocking the action of osteoclasts, thereby reducing undesired movements. PMID:26560822

  4. Extraction treatment of an adult patient with severe bimaxillary dentoalveolar protrusion using microscrew anchorage

    Institute of Scientific and Technical Information of China (English)

    OUYANG Li; ZHOU Yan-heng; FU Min-kui; DING Peng

    2007-01-01

    @@ Bimaxillary dentoalveolar protrusion is one of the most prevalent malocclusion in Asian population,1 Traditionally, orthodontic treatment often involves the extraction of four first premolars2 and demands the least amount of anchorage loss, therefore headgear used to be an unavoid- able fate of these patients.

  5. 75 FR 23804 - Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK...

    Science.gov (United States)

    2010-05-04

    ... National Park Service Notice of Inventory Completion: Alaska State Office, Bureau of Land Management... completion of an inventory of human remains and associated funerary objects in the control of the U.S. Department of the Interior, Bureau of Land Management, Alaska State Office, Anchorage, AK, and in...

  6. 76 FR 80394 - Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK

    Science.gov (United States)

    2011-12-23

    ... Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Alaska State Office, Bureau of Land Management has... completion of an inventory of human remains in the control of the Bureau of Land Management (BLM) that...

  7. 33 CFR 110.220 - Pacific Ocean at San Nicolas Island, Calif.; restricted anchorage areas.

    Science.gov (United States)

    2010-07-01

    ... Pacific Ocean at San Nicolas Island, Calif.; restricted anchorage areas. (a) The restricted areas—(1) East area. All waters within a circle having a radius of one nautical mile centered at latitude 33°13′45... approximately 101°, 420 yards, from San Nicolas Island East End Light. (2) West area. Shoreward of a...

  8. Three-dimensional finite element analysis of a newly designed onplant miniplate anchorage system.

    Science.gov (United States)

    Liu, Lin; Qu, Yin-Ying; Jiang, Li-Jun; Zhou, Qian; Tang, Tian-Qi

    2016-06-01

    The purpose of this research was to evaluate the structural stress and deformation of a newly designed onplant miniplate anchorage system compared to a standard anchorage system. A bone block integrated with a novel miniplate and fixation screw system was simulated in a three-dimensional model and subjected to force at different directions. The stress distribution and deformation of the miniplate system and cortical bone were evaluated using the three-dimensional finite element method. The results showed that the stress on the plate system and bone was linearly proportional to the force magnitude and was higher when the force was in a vertical direction (Y-axis). Stress and deformation values of the two screws (screw 1 and 2) were asymmetric when the force was added along Y-axis and was greater in screw 1. The highest deformation value of the screws was 7.5148 μm, much smaller than the limit value. The load was decreased for each single miniscrew, and the ability of the new anchorage system to bear the load was also enhanced to some degree. It was suggested that the newly designed onplant miniplate anchorage system is effective, easily implanted and minimally invasive.

  9. Oxidative Stress Modulates DNA Methylation during Melanocyte Anchorage Blockade Associated with Malignant Transformation

    Directory of Open Access Journals (Sweden)

    Ana C.E. Campos

    2007-12-01

    Full Text Available Both oxidative/nitrosative stress and alterations in DNA methylation are observed during carcinogenesis of different tumor types, but no clear correlation between these events has been demonstrated until now. Melanoma cell lines were previously established after submitting the nontumorigenic melanocyte lineage, melan-a, to cycles of anchorage blockade. In this work, increased intracellular oxidative species and nitric oxide levels, as well as alterations in the DNA methylation, were observed after melan-a detachment, which were also associated with a decrease in intracellular homocysteine (Hey, an element in the methionine (universal methyl donor cycle. This alteration was accompanied by increase in glutathione (GSH levels and methylated DNA content. Furthermore, a significant increase in dnmti and 3b expression was identified along melan-a anchorage blockade. LG-Nitro-L-arginine methyl esther (L-NAME, known as a nitric oxide synthase (NOS inhibitor, and N-acetyl-L-cysteine (NAC prevented the increase in global DNA methylation, as well as the increase in dnmti and 3b expression, observed during melan-a detachment. Interestingly, both L-NAME and NAC did not inhibit nitric oxide (NO production in these cells, but abrogated superoxide anion production during anchorage blockade. In conclusion, oxidative stress observed during melanocyte anchorage blockade seems to modulate DNA methylation levels and may directly contribute to the acquisition of an anoikis-resistant phenotype through an epigenetic mechanism.

  10. Biofilm formation on surface characterized micro-implants for skeletal anchorage in orthodontics

    NARCIS (Netherlands)

    Chin, Yeen; Sandham, John; de Vries, Jacob; van der Mei, Henderina; Busscher, Hendrik

    2007-01-01

    Micro-implants are increasingly popular in clinical orthodontics to effect skeletal anchorage. However, biofilm formation on their surfaces and subsequent infection of peri-implant tissues can result in either exfoliation or surgical removal of these devices. The present study aimed to assess biofil

  11. Are orthodontic distalizers reinforced with the temporary skeletal anchorage devices effective?

    NARCIS (Netherlands)

    Fudalej, P.S.; Antoszewska, J.

    2011-01-01

    INTRODUCTION: Our objective was to perform a systematic review of studies pertaining to the distalization of teeth with appliances reinforced with temporary skeletal anchorage devices. METHODS: PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Knowledge, Ovid, and Scopus were se

  12. Evaluating School Wellness Policy in Curbing Childhood Obesity in Anchorage, Alaska

    Science.gov (United States)

    Parsons, Wendy G.; Garcia, Gabriel M.; Hoffman, Pamela K.

    2014-01-01

    In 2006, the Anchorage School District implemented a school wellness policy to address the problem of obesity among its elementary-aged students. We assessed whether the addition of this policy is effective in protecting or preventing students from becoming overweight/obese over time. The methods involved following two cohorts of students for 5…

  13. The benefit of differential moment concept in managing posterior anchorage and avoiding bite deepening

    Directory of Open Access Journals (Sweden)

    Harryanto Wijaya

    2012-09-01

    Full Text Available Background: Anchorage is one of the major concerns in orthodontic space closure. Various methods have been proposed to enhance posterior anchorage in space closure such as headgear, Nance holding appliance, and micro implant as temporary anchorage devices. However, several issues such as patient's compliance, appliance effectiveness, and cost of the device become many clinicians concern. The differential moment concept in segmented arch is a technique that requires no patient compliance but can effectively manage posterior anchorage and avoid bite deepening by careful application of forces and moments. Purpose: The purpose of this case report is to show the use of differential moment concept in segmented arch technique to manage posterior anchorage and to avoid bite deepening. Case: A 21 years old female patient with protrusive teeth as her chief complaint was treated using fixed orthodontic appliance. Case management: The treatment included four first bicuspid extraction and space closure utilizing differential moment concept in segmented arch. Conclusion: It can be concluded that application of differential moment concept in segmented arch technique is a non invasive, compliance independent, effective, and cost efficient method to manage posterior anchorage and to avoid bite deepening.latar belakang: Penjangkaran merupakan salah satu aspek yang sering kali menjadi masalah dalam penutupan ruang pada perawatan ortodonti. Berbagai metode disarankan untuk memperkuat penjangkaran posterior dalam penutupan ruang seperti headgear, piranti penahan Nance, dan implan mikro sebagai alat penjangkar sementara. Namun demikian, beberapa hal seperti kerjasama pasien, efektivitas piranti, dan biaya dari alat-alat tersebut sering menjadi perhatian/pertimbangan bagi klinisi. Konsep momen diferensial pada segmented arch adalah suatu cara yang efektif untuk memperkuat penjangkaran dan menghindari pendalaman gigitan tanpa memerlukan kerjasama pasien. tujuan

  14. Anchorage of titanium implants with different surface characteristics: an experimental study in rabbits

    DEFF Research Database (Denmark)

    Gotfredsen, K; Berglundh, T; Lindhe, J

    2000-01-01

    ) TiO2-blasted with particles of grain size 10 to 53 microns; (3) TiO2-blasted, grain size 63 to 90 microns; (4) TiO2-blasted, grain size 90 to 125 microns; (5) titanium plasma-sprayed (TPS). The surface topography was determined by the use of an optical instrument. Twelve rabbits, divided into two...... in group B were 9 and 12 weeks. The tibiae were removed, and each implant site was dissected, fixed, and embedded in light-curing resin. Ground sections were made, and the peri-implant bone was analyzed using fluorescence and light microscopy. RESULTS: The turned implants had the lowest Sa and Sy values......: The present study demonstrated that a clear relation exists between surface roughness, described in Sa values, and implant anchorage assessed by RMT measurements. The anchorage appeared to increase with the maturation of bone tissue during healing....

  15. A genetic algorithm for dynamic parameters reverse deduction of integrated anchorage system

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In the analysis of the system of anchoring bar and wall rock in small strain and longitudinal vibration dynamic response, the influence of the cement grouting as well as the rock layer on the anchor bar can be evaluated as the two kinds of parameters: the dynamic stiffness and the damp, which are the vital reference of the anchorage quality. Based on the analytic solution to the dynamic equation of the integrated anchor bar, the new approach which combines genetic algorithm and the toolbox of Matlab is applied to solve the problem of multi-parameters reverse deduction for integrated anchorage system in dynamic testing. Using the traits of the self-organizing, self-adapting and the fast convergence speed of the genetic algorithm, the optimum of all possible solutions to dynamic parameters is obtained by calculating the project instances. Examples show that the method presented in this paper is effective and reliable.

  16. Numerical implementation of multiple peeling theory and its application to spider web anchorages.

    Science.gov (United States)

    Brely, Lucas; Bosia, Federico; Pugno, Nicola M

    2015-02-06

    Adhesion of spider web anchorages has been studied in recent years, including the specific functionalities achieved through different architectures. To better understand the delamination mechanisms of these and other biological or artificial fibrillar adhesives, and how their adhesion can be optimized, we develop a novel numerical model to simulate the multiple peeling of structures with arbitrary branching and adhesion angles, including complex architectures. The numerical model is based on a recently developed multiple peeling theory, which extends the energy-based single peeling theory of Kendall, and can be applied to arbitrarily complex structures. In particular, we numerically show that a multiple peeling problem can be treated as the superposition of single peeling configurations even for complex structures. Finally, we apply the developed numerical approach to study spider web anchorages, showing how their function is achieved through optimal geometrical configurations.

  17. Inclusion of CFRP-Epoxy Composite for End Anchorage in NSM-Epoxy Strengthened Beams

    Directory of Open Access Journals (Sweden)

    Md. Akter Hosen

    2015-01-01

    Full Text Available Nowadays, the use of near surface mounted (NSM technique strengthening reinforced concrete (RC structural members is going very popular. The failure modes of NSM strengthened reinforced concrete (RC beams have been shown to be largely due to premature failure such as concrete cover separation. In this study, CFRP U-wrap end anchorage with CFRP fabrics was used to eliminate the concrete cover separation failure. A total of eight RC rectangular beam specimens of 125 mm width, 250 mm depth, and 2300 mm length were tested. One specimen was kept unstrengthened as a reference; three specimens were strengthened with NSM steel bars and the remaining four specimens were strengthened with NSM steel bars together with the U-wrap end anchorage. The experimental results showed that wrapped strengthened beams had higher flexural strength and superior ductility performance. The results also show that these beams had less deflection, strain, crack width, and spacing.

  18. Impedance-Based Cable Force Monitoring in Tendon-Anchorage Using Portable PZT-Interface Technique

    Directory of Open Access Journals (Sweden)

    Thanh-Canh Huynh

    2014-01-01

    Full Text Available In this paper, a portable PZT interface for tension force monitoring in the cable-anchorage subsystem is developed. Firstly, the theoretical background of the impedance-based method is presented. A few damage evaluation approaches are outlined to quantify the variation of impedance signatures. Secondly, a portable PZT interface is designed to monitor impedance signatures from the cable-anchorage subsystem. One degree-of-freedom analytical model of the PZT interface is established to explain how to represent the loss of cable force from the change in the electromechanical impedance of the PZT interface as well as reducing the sensitive frequency band by implementing the interface device. Finally, the applicability of the proposed PZT-interface technique is experimentally evaluated for cable force-loss monitoring in a lab-scaled test structure.

  19. Impedance monitoring at tendon-anchorage via mountable PZT interface and temperature-effect compensation

    Science.gov (United States)

    Huynh, Thanh-Canh; Nguyen, Tuan-Cuong; Choi, Sang-Hoon; Kim, Jeong-Tae

    2016-04-01

    In this study, the pre-stress force in pre-stressed concrete (PSC) girders is monitored via mountable PZT interface under varying temperature. Firstly, an impedance-based technique using mountable PZT interface is proposed for pre-stress-loss monitoring in tendon-anchorage systems. A cross correlation-based temperature-effect compensation algorithm using an effective frequency shift (EFS) of impedance signatures is visited. Secondly, lab-scale experiments are performed on a PSC girder instrumented with a mountable PZT interface at tendon-anchorage. A series of temperature variation and pre-stress-loss events are simulated for the lab-scale PSC girder. Thirdly, the feasibility of the mountable PZT interface for pre-stress-loss monitoring in tendon-anchorage is experimentally verified under constant temperature conditions. Finally, the PZT interface device is examined for pre-stress-loss monitoring under temperature changes to validate its applicability. The temperature effect on impedance signatures is compensated by minimizing cross-correlation deviation between impedance patterns of the mountable PZT interface.

  20. Strontium ranelate improved tooth anchorage and reduced root resorption in orthodontic treatment of rats.

    Science.gov (United States)

    Kirschneck, Christian; Wolf, Michael; Reicheneder, Claudia; Wahlmann, Ulrich; Proff, Peter; Roemer, Piero

    2014-12-05

    The anchorage mechanisms currently used in orthodontic treatment have various disadvantages. The objective of this study was to determine the applicability of the osteoporosis medication strontium ranelate in pharmacologically induced orthodontic tooth anchorage. In 48 male Wistar rats, a constant orthodontic force of 0.25 N was reciprocally applied to the upper first molar and the incisors by means of a Sentalloy(®) closed coil spring for two to four weeks. 50% of the animals received strontium ranelate at a daily oral dosage of 900 mg per kilogramme of body weight. Bioavailability was determined by blood analyses. The extent of tooth movement was measured both optometrically and cephalometrically (CBCT). Relative alveolar gene expression of osteoclastic markers and OPG-RANKL was assessed by qRT-PCR and root resorption area and osteoclastic activity were determined in TRAP-stained histologic sections of the alveolar process. Compared to controls, the animals treated with strontium ranelate showed up to 40% less tooth movement after four weeks of orthodontic treatment. Gene expression and histologic analyses showed significantly less osteoclastic activity and a significantly smaller root resorption area. Blood analyses confirmed sufficient bioavailability of strontium ranelate. Because of its pharmacologic effects on bone metabolism, strontium ranelate significantly reduced tooth movement and root resorption in orthodontic treatment of rats. Strontium ranelate may be a viable agent for inducing tooth anchorage and reducing undesired root resorption in orthodontic treatment. Patients under medication of strontium ranelate have to expect prolonged orthodontic treatment times.

  1. Effectiveness of interceptive treatment of class III malocclusions with skeletal anchorage: A systematic review and meta-analysis

    Science.gov (United States)

    Rodríguez de Guzmán-Barrera, Jorge; Sáez Martínez, Carla; Boronat-Catalá, Montserrat; Montiel-Company, Jose María; Paredes-Gallardo, Vanessa; Gandía-Franco, José Luís; Almerich-Silla, José Manuel; Bellot-Arcís, Carlos

    2017-01-01

    Recently, new strategies for treating class III malocclusions have appeared. Skeletal anchorage appears to reduce the dentoalveolar effects while maximising the orthopaedic effect in growing patients. The purpose of this systematic review and meta-analysis is to examine the effectiveness of bone anchorage devices for interceptive treatment of skeletal class III malocclusions. Searches were made in the Pubmed, Embase, Scopus and Cochrane databases, as well as in a grey literature database, and were complemented by hand-searching. The criteria for eligibility were: patients who had undergone orthodontic treatment with skeletal anchorage (miniplates and miniscrews). Patients with syndromes or craniofacial deformities or who had undergone maxillofacial surgery were excluded. The following variables were recorded for each article: author, year of publication, type of study, sample size, dropouts, demographic variables, treatment carried out, radiographic study (2D or 3D), follow-up time, and quality of the articles on the Newcastle-Ottawa Scale. The means and confidence intervals of the following variables were employed: Wits, overjet, ANB, SNA and SNB. Initially, 239 articles were identified. After removing the duplicates and applying the selection criteria, 9 were included in the qualitative synthesis and 7 in the quantitative synthesis (meta-analysis). It may be concluded that skeletal anchorage is an effective treatment for improving skeletal Class III malocclusion, but when compared with other traditional treatments such as disjunction and face mask, there is no clear evidence that skeletal anchorage improves the results. PMID:28328995

  2. Detection of bond failure in the anchorage zone of reinforced concrete beams via acoustic emission monitoring

    Science.gov (United States)

    Abouhussien, Ahmed A.; Hassan, Assem A. A.

    2016-07-01

    In this study, acoustic emission (AE) monitoring was utilised to identify the onset of bond failure in reinforced concrete beams. Beam anchorage specimens were designed and tested to fail in bond in the anchorage zone. The specimens included four 250 × 250 × 1500 mm beams with four variable bonded lengths (100, 200, 300, and 400 mm). Meanwhile, an additional 250 × 250 × 2440 mm beam, with 200 mm bonded length, was tested to investigate the influence of sensor location on the identification of bond damage. All beams were tested under four-point loading setup and continuously monitored using three distributed AE sensors. These attached sensors were exploited to record AE signals resulting from both cracking and bond deterioration until failure. The variations in the number of AE hits and cumulative signal strength (CSS) versus test time were evaluated to achieve early detection of crack growth and bar slippage. In addition, AE intensity analysis was performed on signal strength of collected AE signals to develop two additional parameters: historic index (H (t)) and severity (S r). The analysis of these AE parameters enabled an early detection of both first cracks (at almost the mid-span of the beam) and bar slip in either of the anchorage zones at the beams’ end before their visual observation, regardless of sensor location. The results also demonstrated a clear correlation between the damage level in terms of crack development/measured free end bar slip and AE parameters (number of hits, CSS, H(t), and S r).

  3. Impact of a new gasoline benzene regulation on ambient air pollutants in Anchorage, Alaska

    Science.gov (United States)

    Yano, Yuriko; Morris, Stephen S.; Salerno, Christopher; Schlapia, Anne M.; Stichick, Mathew

    2016-05-01

    The purpose of this study was to quantify the impact of a new U.S. Environmental Protection Agency (EPA) standard that limits the amount of benzene allowed in gasoline on ambient benzene concentrations. This new standard, together with two companion regulations that limit cold-temperature automotive emissions and the permeability of portable fuel containers, was expected to lower the levels of ambient benzene and other volatile organic compounds (VOCs) nationwide. In this study the impact of the gasoline benzene standard was evaluated in Anchorage, Alaska in a two-phase ambient air monitoring study conducted before and after the new gasoline standard was implemented. Gasoline sold by Anchorage retailers was also evaluated in each phase to determine the content of benzene and other gasoline components. The average benzene content in Anchorage gasoline was reduced by 70%, from 5.05% (w/w) to 1.53% (w/w) following the implementation of the standard. The annual mean ambient benzene concentration fell by 51%, from 0.99 ppbv in Phase 1 to 0.49 ppbv in Phase 2. Analysis suggests the change in gasoline benzene content alone reduced benzene emissions by 46%. The changes in toluene, ethylbenzene, and xylene content in gasoline between Phase 1 and 2 were relatively small and the differences in the mean ambient concentrations of these compounds between phases were modest. Our results suggest that cold winter communities in high latitude and mountainous regions may benefit more from the gasoline benzene standard because of high benzene emissions resulting from vehicle cold start and a tendency to develop atmospheric stagnation conditions in the winter.

  4. Concentrations of fecal coliform bacteria in creeks, Anchorage, Alaska, August and September 1998

    Science.gov (United States)

    Dorava, Joseph M.; Love, Andra

    1999-01-01

    Water samples were collected from five creeks in undeveloped, semi-developed, and developed areas of Anchorage, Alaska, during August and September 1998 to determine concentrations of fecal coliform bacteria. In undeveloped areas of Ship, Chester, and Campbell Creeks, and the semi-developed area of Rabbit Creek, concentrations of fecal coliform bacteria ranged from less than 1 to 16 colonies per 100 milliliters of water. In the semi-developed area of Little Rabbit Creek, concentrations ranged from 30 to 860 colonies per 100 milliliters of water. In developed areas of the creeks, concentrations of fecal coliform bacteria ranged from 6 to 80 colonies per 100 milliliters of water.

  5. Dental Extrusion with Orthodontic Miniscrew Anchorage: A Case Report Describing a Modified Method

    Directory of Open Access Journals (Sweden)

    Ricardo Fidos Horliana

    2015-01-01

    Full Text Available In recent years, the skeletal anchorage through miniscrews has expanded the treatment options in orthodontics (Yamaguchi et al., 2012. We hereby present a modified method for tooth extrusion for cases where crown-lengthening surgery is contraindicated for aesthetic reasons. This modified method uses three orthodontic appliances: a mini-implant, an orthodontic wire, and a bracket. The aim of this case report was to increase the length of the clinical crown of a fractured tooth (tooth 23 by means of an orthodontic extrusion with the modified method of Roth and Diedrich.

  6. Patients’ and orthodontists’ perceptions of miniplates used for temporary skeletal anchorage: A prospective study

    Science.gov (United States)

    Cornelis, Marie A.; Scheffler, Nicole R.; Nyssen-Behets, Catherine; De Clerck, Hugo J.; Tulloch, J. F. Camilla

    2009-01-01

    Introduction Temporary skeletal anchorage is a relatively recent addition to orthodontic treatment. Surgical miniplates, modified with intraoral attachments, provide an alternative to miniscrews for skeletal anchorage. In this study, we wanted to determine patients’ and providers’ perceptions of miniplate use during orthodontic treatment. Methods Consecutive patients having miniplates placed as part of their treatment completed questionnaires about their experiences during surgery and orthodontic treatment. A total of 200 miniplates were placed for 97 patients. The 30 orthodontists treating these patients also completed questionnaires concerning miniplate success, handling complexity, and whether these devices simplified treatment. Results The success rate was 92.5%. The devices were well tolerated by the patients. After a year, 72% of the patients reported that they did not mind having the implant, and 82% said that the surgical experience was better than expected, with little or no pain. The most frequent problems were postsurgical swelling, lasting 5 days on average, and cheek irritation experienced initially by more than a third of the patients, but it lessened over time. The clinicians reported that these devices were easy to use and greatly simplified orthodontic treatment. Conclusions Miniplates are well accepted by patients and providers and are a safe and effective adjunct for complex orthodontic treatments. PMID:18174066

  7. Modified Miniplates for Temporary Skeletal Anchorage in Orthodontics: Placement and Removal Surgeries

    Science.gov (United States)

    Cornelis, Marie A.; Scheffler, Nicole R.; Mahy, Pierre; Siciliano, Sergio; De Clerck, Hugo J.; Tulloch, J.F. Camilla

    2009-01-01

    Purpose Skeletal anchorage systems are increasingly used in orthodontics. This article describes the techniques of placement and removal of modified surgical miniplates used for temporary orthodontic anchorage and reports surgeons’ perceptions of their use. Patients and Methods We enrolled 97 consecutive orthodontic patients having miniplates placed as an adjunct to treatment. A total of 200 miniplates were placed by 9 oral surgeons. Patients and surgeons completed questionnaires after placement and removal surgeries. Results Fifteen miniplates needed to be removed prematurely. Antibiotics and anti-inflammatories were generally prescribed after placement but not after removal surgery. Most surgeries were performed with the patient under local anesthesia. Placement surgery lasted on average between 15 and 30 minutes per plate and was considered by the surgeons to be very easy to moderately easy. The surgery to remove the miniplates was considered easier and took less time. The patients’ chief complaint was swelling, lasting on average 5.3 ± 2.8 days after placement and 4.5 ± 2.6 days after removal. Conclusions Although miniplate placement/removal surgery requires the elevation of a flap, this was considered an easy and relatively short surgical procedure that can typically be performed with the patient under local anesthesia without complications, and it may be considered a safe and effective adjunct for orthodontic treatment. PMID:18571028

  8. Skeletal anchorage for orthodontic correction of severe maxillary protrusion after previous orthodontic treatment.

    Science.gov (United States)

    Tanaka, Eiji; Nishi-Sasaki, Akiko; Hasegawa, Takuro; Nishio, Clarice; Kawai, Nobuhiko; Tanne, Kazuo

    2008-01-01

    The correction of a severe maxillary protrusion in an adult by distal movement of the maxillary molars has been one of the most difficult biomechanical problems in orthodontics. This article reports on the treatment of an adult case of severe maxillary protrusion and a large overjet treated with a skeletal anchorage system. A female patient, age 22 years and 3 months, complained of the difficulty of lip closure due to severe maxillary protrusion with a gummy smile. Overjet and overbite were +7.6 mm and -0.9 mm, respectively. She had a history of orthodontic treatment in which her maxillary first premolars were extracted. In order to conduct distal movement of the maxillary molars, anchor plates were placed in the zygomatic process. After achieving a Class I molar relationship, retraction and intrusion of the maxillary incisors were performed. After a 2-year treatment, an acceptable occlusion was achieved with a Class I molar relationship. Her convex facial profile with upper lip protrusion was considerably improved, and the lips showed less tension in lip closure. After a 2-year retention period, an acceptable occlusion was maintained without recurrence of maxillary protrusion, indicating a stability of the occlusion. The result of this treatment indicated that skeletal anchorage is of great importance as a remedy for achieving intrusion and retraction of the maxillary incisors in cases of severe maxillary protrusion with a patient who had previous orthodontic treatment.

  9. Behaviour of plate anchorage in plate-reinforced composite coupling beams.

    Science.gov (United States)

    Lam, W Y; Li, Lingzhi; Su, R K L; Pam, H J

    2013-01-01

    As a new alternative design, plate-reinforced composite (PRC) coupling beam achieves enhanced strength and ductility by embedding a vertical steel plate into a conventionally reinforced concrete (RC) coupling beam. Based on a nonlinear finite element model developed in the authors' previous study, a parametric study presented in this paper has been carried out to investigate the influence of several key parameters on the overall performance of PRC coupling beams. The effects of steel plate geometry, span-to-depth ratio of beams, and steel reinforcement ratios at beam spans and in wall regions are quantified. It is found that the anchorage length of the steel plate is primarily controlled by the span-to-depth ratio of the beam. Based on the numerical results, a design curve is proposed for determining the anchorage length of the steel plate. The load-carrying capacity of short PRC coupling beams with high steel ratio is found to be controlled by the steel ratio of wall piers. The maximum shear stress of PRC coupling beams should be limited to 15 MPa.

  10. Prestressed CFRP Strips with Gradient Anchorage for Structural Concrete Retrofitting: Experiments and Numerical Modeling

    Directory of Open Access Journals (Sweden)

    Julien Michels

    2014-01-01

    Full Text Available This paper presents a study on the load carrying capacity of reinforced concrete (RC beams strengthened with externally bonded (EB carbon fiber reinforced polymer (CFRP strips prestressed up to 0.6% in strain. At the strip ends, the innovative gradient anchorage is used instead of conventional mechanical fasteners. This method, based on the epoxy resin’s ability to rapidly cure under high temperatures, foresees a sector-wise heating followed by a gradual decrease of the initial prestress force towards the strip ends. The experimental investigation shows a promising structural behavior, resulting in high strip tensile strains, eventually almost reaching tensile failure of the composite strip. Additionally, ductility when considering deflection at steel yielding and at ultimate load is satisfying, too. From a practical point of view, it is demonstrated that premature strip grinding in the anchorage zone is not beneficial. In addition, a non-commercial 1D finite element code has been enlarged to an EB reinforcement with prestressed composite strips. A bilinear bond stress-slip relation obtained in earlier investigations is introduced as an additional failure criterion to the code. The numerical code is able to almost perfectly predict the overall structural behavior. Furthermore, the calculations are used for comparison purposes between an initially unstressed and a prestressed externally bonded composite reinforcement. The increase in cracking and yielding load, as well as differences in structural stiffness are apparent.

  11. 77 FR 66942 - Anchorages; Lower Mississippi River, Above Head of Passes, Convent, LA and Point Pleasant, LA

    Science.gov (United States)

    2012-11-08

    ... INFORMATION section below for instructions on submitting comments. To avoid duplication, please use only one... anchored or moored within the anchorage areas. D. Regulatory Analyses We developed this proposed rule after... Homeland Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide the...

  12. Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth

    Energy Technology Data Exchange (ETDEWEB)

    Jokilehto, Terhi [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Turku Graduate School of Biomedical Sciences, Turku (Finland); Hoegel, Heidi [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Heikkinen, Pekka [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Turku Graduate School of Biomedical Sciences, Turku (Finland); Rantanen, Krista [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Elenius, Klaus [Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital, Turku (Finland); Department of Medical Biochemistry and Genetics, University of Turku and Turku University Hospital, Turku (Finland); Sundstroem, Jari [Department of Pathology, University of Turku and Turku University Hospital, Turku (Finland); Jaakkola, Panu M. [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital, Turku (Finland)

    2010-04-15

    Cellular oxygen tension is sensed by a family of prolyl hydroxylases (PHD1-3) that regulate the degradation of hypoxia-inducible factors (HIF-1{alpha} and -2{alpha}). The PHD2 isoform is considered as the main downregulator of HIF in normoxia. Our previous results have shown that nuclear translocation of PHD2 associates with poorly differentiated tumor phenotype implying that nuclear PHD2 expression is advantageous for tumor growth. Here we show that a pool of PHD2 is shuttled between the nucleus and the cytoplasm. In line with this, accumulation of wild type PHD2 in the nucleus was detected in human colon adenocarcinomas and in cultured carcinoma cells. The PHD2 isoforms showing high nuclear expression increased anchorage-independent carcinoma cell growth. However, retention of PHD2 in the cytoplasm inhibited the anchorage-independent cell growth. A region that inhibits the nuclear localization of PHD2 was identified and the deletion of the region promoted anchorage-independent growth of carcinoma cells. Finally, the cytoplasmic PHD2, as compared with the nuclear PHD2, less efficiently downregulated HIF expression. Forced HIF-1{alpha} or -2{alpha} expression decreased and attenuation of HIF expression increased the anchorage-independent cell growth. However, hydroxylase-inactivating mutations in PHD2 had no effect on cell growth. The data imply that nuclear PHD2 localization promotes malignant cancer phenotype.

  13. 33 CFR 165.110 - Safety and Security Zone; Liquefied Natural Gas Carrier Transits and Anchorage Operations, Boston...

    Science.gov (United States)

    2010-07-01

    ...; Liquefied Natural Gas Carrier Transits and Anchorage Operations, Boston, Massachusetts. 165.110 Section 165... Limited Access Areas First Coast Guard District § 165.110 Safety and Security Zone; Liquefied Natural Gas... ahead and one mile astern, and 500 yards on each side of any liquefied natural gas carrier (LNGC)...

  14. The "Real Self" and Inauthenticity: The Importance of Self-Concept Anchorage for Emotional Experiences in the Workplace

    Science.gov (United States)

    Sloan, Melissa M.

    2007-01-01

    I examine the utility of self-concept anchorage (as described by Turner 1976) in the analysis of inauthenticity in the workplace. As controlling internally felt emotion may distance the worker from her true feelings or true self, the management of emotion in the workplace can produce feelings of inauthenticity in the worker. This relationship has…

  15. Orthodontic retreatment using anchorage with miniplate to camouflage a Class III skeletal pattern

    Directory of Open Access Journals (Sweden)

    Marcel Marchiori Farret

    Full Text Available ABSTRACT This manuscript describes the treatment of a 27-year-old patient who was previously treated with two maxillary first premolar extractions. The patient had skeletal Class III malocclusion, Class III canine relationship, anterior crossbite, and a concave profile. As the patient refused orthognathic surgery, a miniplate was used on the right side of the lower arch as an anchorage unit after the extraction of mandibular first premolars, aiding the retraction of anterior teeth. At the end of treatment, anterior crossbite was corrected, in which first molars and canines were in a Class I relationship, and an excellent intercuspation was reached. Furthermore, patient's profile remarkably improved as a result of mandibular incisor retraction. A 30-month follow-up showed good stability of the results obtained. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO as one of the requirements to become diplomate by the BBO.

  16. Elmendorf AFB, Anchorage, Alaska. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

    Science.gov (United States)

    1979-09-17

    OBSERVATIONS) 260 EjJMENDORF AF0 ALASK /ANCHORAGE 6 6-79 SE ITATION STATION RAMP VEA~sS 505Thm CALL WIATivg 2800-2000 CLA" 40 isA IS EL..) ( CONDItION SPEED) 1...iiiiiiii - - _ l-l nA T A ,1, 1C. is Z’I e(’ ,It .,. - DAILY TEMPERATURES l if ?,52 4C: I L;I1.,-JuIqkI AF, ALA.aVA/Al C1-I!R1t .; ,| ’,i 5 -/ iSA ,;O...2 0. O 3,861.7 .550 8/5 . 1 1 2 14 101 Element (X) ZX9 Z X I Mean No. of Hours w th Temp rtu re < RJh 4418271 60855 69.9 87 870 . F 󈧤F 67F 73F 80F

  17. Orthodontic retreatment using anchorage with miniplate to camouflage a Class III skeletal pattern

    Science.gov (United States)

    Farret, Marcel Marchiori

    2016-01-01

    ABSTRACT This manuscript describes the treatment of a 27-year-old patient who was previously treated with two maxillary first premolar extractions. The patient had skeletal Class III malocclusion, Class III canine relationship, anterior crossbite, and a concave profile. As the patient refused orthognathic surgery, a miniplate was used on the right side of the lower arch as an anchorage unit after the extraction of mandibular first premolars, aiding the retraction of anterior teeth. At the end of treatment, anterior crossbite was corrected, in which first molars and canines were in a Class I relationship, and an excellent intercuspation was reached. Furthermore, patient's profile remarkably improved as a result of mandibular incisor retraction. A 30-month follow-up showed good stability of the results obtained. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as one of the requirements to become diplomate by the BBO. PMID:27409659

  18. Bio-cultural anchorage of the prickly pear cactus in Tlalnepantla (Morelos, Mexico

    Directory of Open Access Journals (Sweden)

    Torres-Salcido, Gerardo

    2016-06-01

    Full Text Available The prickly pear cactus is a source of food with strong bio-cultural anchorage in Mexico. This is due to at least three factors: 1 the nature and heritage of cacti; 2 cultural heritage; and 3 the socio-cultural relationships with historical and symbolic roots that have facilitated knowledge of how to cultivate it and how to use it. The aim of this article is to put factors of territorial anchorage and its historical transformation in context by examining the case of the municipality of Tlalnepantla in the state of Morelos, Mexico. This community has experienced accelerated change due to the exchange of traditional crops for the prickly pear cactus and the integration of farming, commercialization and agro-transformation. Our hypothesis is that the market, internal conflicts and a lack of socio-institutional coordination have put social organization into crisis, favoring the territorial spread of the prickly pear cactus and making the Local Agro-Food Systems (LAFS of Tlalnepantla less competitive. The conclusions highlight important economic and social advances whose roots lie in the strengthening and anchorage of the territory-product. However, circumstances both internal and external to the community persist, such as intra-community conflicts, the international market and cultural paradigm shifts that affect the producers and put consolidation of the LAFS at risk.El nopal es un alimento con un fuerte anclaje bio-cultural en México, propiciado por al menos tres factores: 1 la naturaleza y el patrimonio de cactáceas; 2 el patrimonio cultural; y, 3 las relaciones socio-culturales que han permitido un “saber hacer” y un “saber utilizar” con raíces históricas y simbólicas. El objetivo es situar los factores de anclaje territorial y su transformación histórica tomando como caso el municipio de Tlalnepantla, en el estado de Morelos, México. Esta comunidad ha experimentado un acelerado cambio por la reconversión de los cultivos

  19. The U.S. Department of Energy Office of Indian Energy Policy and Programs, Anchorage, Alaska, Roundtable Summary

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-04-14

    The Anchorage, Alaska Roundtable on Tribal Energy Policy convened at 10:00 a.m., Thursday April 15th, at the downtown Anchorage Hilton. The meeting was held by the Department of Energy (DOE) Office of Indian Energy Policy and Programs (Office of Indian Energy). Tracey LeBeau, Director of the Office of Indian Energy, and Pilar Thomas, Deputy Director-Policy of the Office of Indian Energy, represented DOE. Approximately twenty-seven people attended the meeting, including representatives of three native Alaskan villages, four Alaskan tribal corporations representing more than 40 tribal governments, as well as representatives from tribal associations and conferences. Interested state, federal, and non-profit representatives also were present. A full list of attendees is at the end of this summary. The meeting was facilitated by the Udall Foundation’s U.S. Institute for Environmental Conflict Resolution (U.S. Institute).  

  20. Metallurgical Behavior of Ti-6Al-4V Alloy Mini-Implants as a Temporary Anchorage Device in Orthodontics Applications

    Directory of Open Access Journals (Sweden)

    Mendoza-Bravo Ivan

    2014-01-01

    Full Text Available The application of mini implants as a temporary anchorage device in orthodontics is a new technique that allows the movement of teeth in an efficient and predictable way. Although they have started to be used in Germany, Japan and South Korea, there is still the need to analyze and diffuse the advantages this procedure can offer over the traditional techniques. The objective of this research work was to analyze the integrity of Ti-6Al-4V mini implants temporary employed for 4 months on three patients as an anchorage device. The mini implants were analyzed by means of electron scanning microscopy in order to determine superficial and microstructural changes as well as the interaction with human tissue. Results showed the presence of wear on the thread zone caused during the insertion into the maxilar bone. The adherence of organic tissue was also observed on two mini-implants.

  1. Transdisciplinary treatment of Class III malocclusion using conventional implant-supported anchorage: 10-year posttreatment follow-up

    Directory of Open Access Journals (Sweden)

    Mariana Roennau Lemos Rinaldi

    2015-06-01

    Full Text Available INTRODUCTION: Combined treatment offers advantages for partially edentulous patients. Conventional implants, used as orthodontic anchorage, enable previous orthodontic movement, which provides appropriate space gain for crown insertion. OBJECTIVE: This case report describes the treatment of a 61-year and 10-month-old patient with negative overjet which made ideal prosthetic rehabilitation impossible, thereby hindering dental and facial esthetics. CASE REPORT: After a diagnostic setup, conventional implants were placed in the upper arch to anchor intrusion and retract anterior teeth. Space gain for lateral incisors was achieved in the lower arch by means of an orthodontic appliance. CONCLUSIONS: Integrated planning combining Orthodontics and Implantology provided successful treatment by means of conventional implant-supported anchorage. The resulting occlusal relationship proved stable after 10 years.

  2. Latest Pleistocene advance and collapse of the Matanuska - Knik glacier system, Anchorage Lowland, southern Alaska

    Science.gov (United States)

    Kopczynski, Sarah E.; Kelley, Samuel E.; Lowell, Thomas V.; Evenson, Edward B.; Applegate, Patrick J.

    2017-01-01

    At the end of the last ice age, glacier systems worldwide underwent dramatic retreat. Here, we document the advance and retreat of a glacier system with adjacent marine- and land-based components during the latter part of the Termination. We utilize three lines of evidence: lithologic provenance, geomorphic mapping, and radiocarbon ages derived from lake cores to reconstruct glacier extent and timing of advance and retreat within our study area centered at N 61.50°, W 149.50°, just north of Anchorage, Alaska. Two glaciers, sourced in the Talkeetna and Chugach Mountains, flowed down the Matanuska and Knik Valleys forming a coalesced lobe that advanced onto the Anchorage Lowlands and terminated at Elmendorf Moraine. We use the presence of lithologies unique to the Matanuska catchment in glacial drift to delineate the paleoflow lines and to estimate the suture line of the two glacier systems. The eastern side of the lobe, attributed to ice flow from the Knik Valley, was in contact with elevated marine waters within the Knik Arm fjord, and thus retreat was likely dominated by calving. Geomorphic evidence suggests the western side of the lobe, attributed to ice flow from Matanuska Valley, retreated due to stagnation. We constrain retreat of the combined Matanuska and Knik lobe with thirteen new radiocarbon ages, in addition to previously published radiocarbon ages, and with geomorphic evidence suggesting the retreat occurred in two phases. Retreat from the Elmendorf Moraine began between 16.8 and 16.4 ka BP. A second, faster retreat phase occurred later and was completed by 13.7 ka BP. With the 140 km of total retreat occurring over ∼3000 years or less. This pattern of glacial advance and retreats agrees well with the deglacial histories from the southern sectors of the Cordilleran Ice Sheet, as well as many other alpine glacier systems in the western U.S. and northern Alaska. This consistent behavior of glacier systems may indicate that climate oscillated over

  3. Are temporary anchorage devices truly effective in the treatment of skeletal open bites?

    Science.gov (United States)

    Turkkahraman, Hakan; Sarioglu, Mehmet

    2016-01-01

    Objective: The aims of this study were to evaluate the effects of temporary anchorage devices (TADs) in the treatment of skeletal open bites and to compare the results with untreated controls. Materials and Methods: A total of forty patients with skeletal anterior open bites were assigned to two groups of twenty each. The mean chronological age for the treatment group (14 female, 6 male) was 16.68 ± 2.80 years old, compared with 16.63 ± 2.83 years old for the control group (11 female, 9 male). Titanium miniplates fixed bilaterally to the infrazygomatic crest area were used as TADs and intrusive forces were applied to the posterior teeth with Ni-Ti coil springs. The treatment and normal growth changes were evaluated using 24 measurements (2 angular, 22 linear). Results: Statistically significant differences were found between the groups in Bx, By, Sn/GoGn, Ax-Bx, U6x, U6y, overjet, overbite, SN/OccP, N-Me, Ans-Me, S-Go/N-Me, interpremolar width, and intermolar width (P < 0.05). In the treatment group, statistically significant upper molar intrusion (mean ± standard deviation [SD], 3.59 ± 1.34; 95% confidence interval [CI], 2.96–4.22), posterior rotation of the occlusal plane (mean ± SD, 3.42 ± 2.17; 95% CI, 2.39–4.43), anterior rotation of the mandible (mean ± SD, 2.25 ± 1.91; 95% CI, 1.36–3.14), and resultant overbite improvement (mean ± SD, 4.82 ± 1.53; 95% CI, 4.10–5.53) were found (P < 0.05). Conclusions: Mild to moderate skeletal anterior open bites could easily be treated with TADs without orthognathic surgery. With the rigid anchorage of miniplates, true molar intrusion of up to 4 mm was achieved. With molar intrusion, anterior rotation of the mandible and a significant reduction in anterior face height were determined. PMID:28042256

  4. ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion.

    Science.gov (United States)

    Vigil, Dominico; Kim, Tai Young; Plachco, Ana; Garton, Andrew J; Castaldo, Linda; Pachter, Jonathan A; Dong, Hanqing; Chen, Xin; Tokar, Brianna; Campbell, Sharon L; Der, Channing J

    2012-10-15

    Evidence is emerging that the closely related ROCK1 and ROCK2 serine/threonine kinases support the invasive and metastatic growth of a spectrum of human cancer types. Therefore, inhibitors of ROCK are under preclinical development. However, a key step in their development involves the identification of genetic biomarkers that will predict ROCK inhibitor antitumor activity. One identified mechanism for ROCK activation in cancer involves the loss of function of the DLC1 tumor suppressor gene, which encodes a GTPase activating protein (RhoGAP) for the RhoA and RhoC small GTPases. DLC-1 loss may lead to hyperactivation of RhoA/C and its downstream effectors, the ROCK kinases. We therefore determined whether loss of DLC-1 protein expression identifies non-small cell lung carcinoma (NSCLC) cell lines whose growth and invasion phenotypes are sensitive to ROCK inhibition. We identified and characterized a novel small molecule pharmacologic inhibitor of ROCK and additionally applied genetic approaches to impair ROCK1 and/or ROCK2 activity, and we determined that although NSCLC anchorage-dependent growth was ROCK-independent, both anchorage-independent growth and Matrigel invasion were ROCK-dependent. However, loss of DLC-1 expression did not correlate with ROCK activation or with OXA-06 sensitivity. Unexpectedly, suppression of ROCK1 or ROCK2 expression alone was sufficient to impair anchorage-independent growth, supporting their nonoverlapping roles in oncogenesis. Mechanistically, the block in anchorage-independent growth was associated with accumulation of cells in the G(0)-G(1) phase of the cell cycle, but not increased anoikis. We conclude that ROCK may be a useful therapeutic target for NSCLC.

  5. CD45/CD11b Positive Subsets of Adult Lung Anchorage-Independent Cells Harness Epithelial Stem Cells

    OpenAIRE

    2012-01-01

    Compensatory growth is mediated by multiple cell types that interact during organ repair. To elucidate the relationship between the stem/progenitor cells that proliferate or differentiate and the somatic cells of lung, we utilized a novel ex vivo pneumoexplant system. Applying this technique, we identified a sustained culture of repopulating adult progenitors in the form of free floating anchorage-independent cells (AICs). AICs did not express integrin proteins α5, β3, and β7, and constituted...

  6. Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer

    Science.gov (United States)

    Feng, Ming-Xuan; Wang, Ya-Hui; Yang, Xiao-Mei; He, Ping; Tian, Guang-Ang; Zhang, Xiao-Xin; Li, Qing; Cao, Xiao-Yan; Huo, Yan-Miao; Yang, Min-Wei; Fu, Xue-Liang; Li, Jiao; Liu, De-Jun; Dai, Miao; Wen, Shan-Yun; Gu, Jian-Ren; Hong, Jie; Hua, Rong; Zhang, Zhi-Gang; Sun, Yong-Wei

    2016-01-01

    Epidermal Growth Factor-like repeats and Discoidin I-Like Domains 3 (EDIL3), an extracellular matrix (ECM) protein associated with vascular morphogenesis and remodeling, is commonly upregulated in multiple types of human cancers and correlates with tumor progression. However, its expression pattern and underlying cellular functions in pancreatic ductal adenocarcinoma (PDAC) remain largely unexplored. In current study, we observed that expression of EDIL3 was significantly up-regulated in PDAC compared with normal controls in both cell lines and clinical specimens. In addition, elevated EDIL3 expression was positively correlated with patients’ TNM stage and T classification. Kaplan-Meier analysis indicated that high EDIL3 expression was significantly associated with shorter overall survival times in PDAC patients. Multivariate Cox regression analysis confirmed EDIL3 expression, age, lymph node metastasis and histological differentiation as independent prognostic factors in PDAC. Knockdown of EDIL3 showed no significant influence on cell viability, migration, invasion and starvation-induced apoptosis, but compromised anoikis resistance and anchorage independent tumor growth of PDAC cells. Meanwhile, treatment with recombinant EDIL3 protein markedly promoted anoikis resistance and anchorage independent tumor growth. Mechanistically, we demonstrated that altered protein expression of Bcl-2 family might contribute to the oncogenic activities of EDIL3. In conclusion, this study provides evidences that EDIL3 is a potential predictor and plays an important role in anchorage independent tumor growth of PDAC and EDIL3-related pathways might represent a novel therapeutic strategy for treatment of pancreatic cancer. PMID:26735172

  7. PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells.

    Directory of Open Access Journals (Sweden)

    Sophia Boyoung Lee

    Full Text Available PAX transcription factors play an important role during development and carcinogenesis. In this study, we investigated PAX2 protein levels in melanocytes and melanoma cells by Western Blot and immunofluorescence analysis and characterized the role of PAX2 in the pathogenesis of melanoma. In vitro we found weak PAX2 protein expression in keratinocytes and melanocytes. Compared to melanocytes increased PAX2 protein levels were detectable in melanoma cell lines. Interestingly, in tissue sections of melanoma patients nuclear PAX2 expression strongly correlated with nuclear atypia and the degree of prominent nucleoli, indicating an association of PAX2 with a more atypical cellular phenotype. In addition, with chromatin immunoprecipitation assay, PAX2 overexpression and PAX2 siRNA we present compelling evidence that PAX2 can regulate ADAM10 expression, a metalloproteinase known to play important roles in melanoma metastasis. In human tissue samples we found co-expression of PAX2 and ADAM10 in melanocytes of benign nevi and in melanoma cells of patients with malignant melanoma. Importantly, the downregulation of PAX2 by specific siRNA inhibited the anchorage independent cell growth and decreased the migratory and invasive capacity of melanoma cells. Furthermore, the downregulation of PAX2 abrogated the chemoresistance of melanoma cells against cisplatin, indicating that PAX2 expression mediates cell survival and plays important roles during melanoma progression.

  8. Microbeads and anchorage-dependent eukaryotic cells: the beginning of a new era in biotechnology.

    Science.gov (United States)

    Miller, A O; Menozzi, F D; Dubois, D

    1989-01-01

    Modern methods for the mass cultivation of anchorage-dependent mammalian cells started with the advent of microcarrier technology. Largely for reasons pertaining to their mode of preparation and ease of cultivation, 150-230 microns microbeads have been overwhelmingly adopted and the technology around them developed. To meet high biomass, macroporous microbeads have been developed. Also, the chemistry of the microsupport has been adapted in order to afford better protection of fragile cells to mechanical wear while simultaneously reorienting their differentiation towards the sought aims (production of cytokines, enzymes etc. ...). Future progress depends upon solutions being brought to problems inherent to this new technology (maintenance of steady state conditions of growth etc. ...) as well as to requirements arising from animal cell culture in general (biosensors, bioreactor's design etc. ...). Besides such technical implementations, biology at large is also expected to benefit from the advent of microcarriers in fields as diverse as the preparation of metaphasic chromosomes in bulk, toxicity testing, organ reconstitution following cell transplantation etc.

  9. Oral and dental restoration of wide alveolar cleft using distraction osteogenesis and temporary anchorage devices.

    Science.gov (United States)

    Rachmiel, Adi; Emodi, Omri; Gutmacher, Zvi; Blumenfeld, Israel; Aizenbud, Dror

    2013-12-01

    Closure of large alveolar clefts and restoration by a fixed bridge supported by implants is a challenge in cleft alveolus treatment. A major aesthetic concern with distraction osteogenesis is obtaining a predictable position of the implant in relation to the newly generated bony alveolar ridge. We describe the treatment of a large cleft alveolus and palate reconstruction by distraction osteogenesis utilizing temporary anchorage devices (TADs) followed by a fixed implant-supported bridge. The method consists of segmental bone transport by distraction osteogenesis using a bone-borne distractor to minimize the alveolar cleft, followed by closure of the residual small defect by bone grafting three months later. During the active transport distraction, TADs were used exerting multidirectional forces to control the distraction vector forward and laterally for better interarch relation. A vertical alveolar distraction of the newly reconstructed bone of 15 mm facilitated optimal implant placement. The endosseous implants were osteointegrated and supported a fixed dental prosthesis. In conclusion, the large cleft alveolus defect was repaired in three dimensions by distraction osteogenesis assisted by TADs, and the soft tissues expanded simultaneously. Endosseous implants were introduced in the newly reconstructed bone for a fixed dental prosthesis enabling, rehabilitation of aesthetics, eating and speaking.

  10. The perception of pain following interdental microimplant treatment for skeletal anchorage: a retrospective study.

    Science.gov (United States)

    Chen, Chun-Ming; Chang, Chao-San; Tseng, Yu-Chuan; Hsu, Kun-Rong; Lee, Kun-Tsung; Lee, Huey-Er

    2011-01-01

    During orthodontic therapy, patients frequently complain about pain and discomfort, especially during insertion of fixed appliances. Skeletal anchorage using an interdental microimplant is a new concept in orthodontic treatment. The purpose of this study was to investigate differences and changes in the level of pain among patients in relation to orthodontic microimplant treatments. Forty microimplants were applied to the maxilla as skeletal anchors in the orthodontic treatment. The visual analog scale (VAS) was used to evaluate the patients' perception of pain during this new modality treatment. The premolar extraction VAS core was used as a baseline for the complete orthodontic procedure. The mean VAS score was 35.8 mm at 24 h after premolar extraction. The mean VAS score for insertion and removal of the microimplant 24 h after the operation was 12.3 and 7.8 mm, respectively. Three months after removal of the skeletal anchors, the VAS score had decreased to 3.2 mm and was the same as with the traditional orthodontic treatment. By using the repeated-measure general linear model (GLM), we found that the score 1 day after microimplant placement was significantly less than that 1 day after first premolar extraction or that 1 day after fixed appliance insertion. This result indicates that interdental microimplant did not generate any greater pain than other orthodontic procedures. Therefore, patients were willing to adopt the new orthodontic treatment.

  11. Liquid marbles for high-throughput biological screening of anchorage-dependent cells.

    Science.gov (United States)

    Oliveira, Nuno M; Correia, Clara R; Reis, Rui L; Mano, João F

    2015-01-28

    Stable liquid marbles (LM) are produced by coating liquid droplets with a hydrophobic powder. The used hydrophobic powder is produced by fluorosi-lanization of diatomaceous earth, used before to produce superhydrophobic structures. Here, the use of LM is proposed for high-throughput drug screening on anchorage-dependent cells. To provide the required cell adhesion sites inside the liquid environment of LM, surface-modified poly(l-lactic acid) microparticles are used. A simple method that takes advantage from LM appealing features is presented, such as the ability to inject liquid on LM without disrupting (self-healing ability), and to monitor color changes inside of LM. After promoting cell adhesion, a cytotoxic screening test is performed as a proof of concept. Fe(3+) is used as a model cytotoxic agent and is injected on LM. After incubation, AlamarBlue reagent is injected and used to assess the presence of viable cells, by monitoring color change from blue to red. Color intensity is measured by image processing and the analysis of pictures takes using an ordinary digital camera. The proposed method is fully validated in counterpoint to an MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carbo​xymethoxyphenyl)-2-(4-sulfophenyl)-2H-te​trazolium) colorimetric assay, a well-known method used for the cytotoxicity assessment.

  12. Biomechanical comparison of four different miniscrew types for skeletal anchorage in the mandibulo-maxillary area.

    Science.gov (United States)

    Mischkowski, R A; Kneuertz, P; Florvaag, B; Lazar, F; Koebke, J; Zöller, J E

    2008-10-01

    This study compared four miniscrew types for skeletal anchorage (Aarhus, FAMI, Dual Top and Spider) regarding their biomechanical properties contributing to primary stability. Insertion torque measurements and pull-out tests in axial (0 degrees ) as well as in the 20 degrees and 40 degrees direction were performed. Stiffness of the screw-bone construct was calculated from the load-displacement curve. Conic FAMI and Dual Top screws had higher insertion torques. Insertion torques were raised by drill-free insertion of FAMI and Dual Top screws. Statistically significant differences were found between the 4 screw types in pull-out tests. The highly significant differences between the four screws for peak load in the axial (0 degrees ) and 20 degrees direction were not apparent in 40 degrees angular loads. For the conical screws, peak load values increased in angular compared with axial load. The Dual Top screw achieved the highest values for peak load and stiffness. 12 Dual Top and 1 Spider screw heads fractured in the pull-out tests. A conical drill-free screw design achieves higher primary stability compared with cylindrical self-tapping screws. This effect was more obvious in insertion torque estimations rather than in pull-out tests. The Dual Top screws, although biomechanically superior to other screw types, were most prone to fractures.

  13. Research Progress of the Anchorage Control in Orthodontic Treatment%正畸治疗中支抗控制的研究进展

    Institute of Scientific and Technical Information of China (English)

    刘春利; 肖丹娜

    2015-01-01

    The anchorage control is very important in orthodontic treatment,and good design matters to the success or failure of the treatment.Anchorage control includes two aspects of anchorage strengthening and anchorage saving,which both should be taken into consideration,and joint applied in the process of treat-ment.Effect of orthodontic treatment needs multidimensional performance evaluation,to achieve high quality of treatment,sagittal,vertical,and horizontal control should be done according to patients'vertical bone sur-face type and the type of teeth micromaxillary deformity.Here is to make a review of the common methods to strengthen the anchorage,as well as the emerging of strengthening anchorage design,and the idea of the anchorage saving,and the choices of operational and correctional systems.%正畸治疗中支抗控制至关重要,合理的支抗设计关系到治疗的成败。支抗控制可从支抗加强和支抗节省两方面考虑,并在治疗过程中联合应用。正畸治疗效果需以多维效果评价,为取得优质的治疗效果支抗需根据患者的垂直骨面型、牙颌畸形的类型,在矢状向、垂直向、水平向进行控制。该文就目前常用的加强支抗的方法进行简要概括,同时对新兴加强支抗的设计进行简要总结,并对支抗节省的理念、操作和矫治系统的选择进行综述。

  14. A temporal study of urban development for the municipality of Anchorage, Alaska

    Science.gov (United States)

    Markon, Carl J.

    2003-01-01

    A land use/land cover database was produced for a portion of the Municipality of Anchorage, Alaska to document the temporal and spatial extent of urbanization to assist in the analysis of changes in impervious cover and water quality. Data were derived from black and white and color infrared aerial photography, and satellite imagery from the early 1970's to 2000 in roughly ten‐year increments. Aerial photographs and satellite data were manually interpreted to identify and map land use/land cover classes which were then entered into a geographic information system, attributed, and georeferenced to a U.S. Geological Survey topographic map base. The spatial extent of the study was 31,117 hectares. In the early 1970's, approximately 7,356 hectares (24%) of the study area were mapped as urban developed. During the 30‐year analysis period, the largest increase in urban development occurred between the late 1970's and early 1980's when urban area increased to 12,263 hectares (39%). Between 1980 and 1990, and 1990 and 2000, urban area increased to 12,762 hectares (41%), and 13,980 hectares (45%) respectively. Most development occurred in forested or tall shrub areas, although some also occurred in wetlands. Between 1970 and 2000, close to 1,300 hectares of wetlands were lost due to development. Contrary to this, the amount of lake and pond area increased slightly from 261 hectares in 1973 to 334 hectares in 1980, and reduced to 310 hectares by 2000. The increase was primarily due to the filling in of gravel pits with spring melt water.

  15. Nitrate source indicators in ground water of the Scimitar Subdivision, Peters Creek area, Anchorage, Alaska

    Science.gov (United States)

    Wang, Bronwen; Strelakos, Pat M.; Jokela, Brett

    2000-01-01

    A combination of aqueous chemistry, isotopic measurement, and in situ tracers were used to study the possible nitrate sources, the factors contributing to the spatial distribution of nitrate, and possible septic system influence in the ground water in the Scimitar Subdivision, Municipality of Anchorage, Alaska. Two water types were distinguished on the basis of the major ion chemistry: (1) a calcium sodium carbonate water, which was associated with isotopically heavier boron and with chlorofluorocarbons (CFC's) that were in the range expected from equilibration with the atmosphere (group A water) and (2) a calcium magnesium carbonate water, which was associated with elevated nitrate, chloride, and magnesium concentrations, generally isotopically lighter boron, and CFC's concentrations that were generally in excess of that expected from equilibration with the atmosphere (group B water). Water from wells in group B had nitrate concentrations that were greater than 3 milligrams per liter, whereas those in group A had nitrate concentrations of 0.2 milligram per liter or less. Nitrate does not appear to be undergoing extensive transformation in the ground-water system and behaves as a conservative ion. The major ion chemistry trends and the presence of CFC's in excess of an atmospheric source for group B wells are consistent with waste-water influences. The spatial distribution of the nitrate among wells is likely due to the magnitude of this influence on any given well. Using an expanded data set composed of 16 wells sampled only for nitrate concentration, a significant difference in the static water level relative to bedrock was found. Well water samples with less than 1 milligram per liter nitrate had static water levels within the bedrock, whereas those samples with greater than 1 milligram per liter nitrate had static water levels near or above the top of the bedrock. This observation would be consistent with a conceptual model of a low-nitrate fractured bedrock

  16. Recorded earthquake responses from the integrated seismic monitoring network of the Atwood Building, Anchorage, Alaska

    Science.gov (United States)

    Celebi, M.

    2006-01-01

    An integrated seismic monitoring system with a total of 53 channels of accelerometers is now operating in and at the nearby free-field site of the 20-story steel-framed Atwood Building in highly seismic Anchorage, Alaska. The building has a single-story basement and a reinforced concrete foundation without piles. The monitoring system comprises a 32-channel structural array and a 21-channel site array. Accelerometers are deployed on 10 levels of the building to assess translational, torsional, and rocking motions, interstory drift (displacement) between selected pairs of adjacent floors, and average drift between floors. The site array, located approximately a city block from the building, comprises seven triaxial accelerometers, one at the surface and six in boreholes ranging in depths from 15 to 200 feet (???5-60 meters). The arrays have already recorded low-amplitude shaking responses of the building and the site caused by numerous earthquakes at distances ranging from tens to a couple of hundred kilometers. Data from an earthquake that occurred 186 km away traces the propagation of waves from the deepest borehole to the roof of the building in approximately 0.5 seconds. Fundamental structural frequencies [0.58 Hz (NS) and 0.47 Hz (EW)], low damping percentages (2-4%), mode coupling, and beating effects are identified. The fundamental site frequency at approximately 1.5 Hz is close to the second modal frequencies (1.83 Hz NS and 1.43 EW) of the building, which may cause resonance of the building. Additional earthquakes prove repeatability of these characteristics; however, stronger shaking may alter these conclusions. ?? 2006, Earthquake Engineering Research Institute.

  17. Tongue resting pressure of the tongue anchorage pad in different body positions: a pilot study.

    Science.gov (United States)

    Zeng, J; Xu, K; Gao, X; Xu, T

    2015-06-01

    We designed a modified transpalatal arch (tongue anchorage pad, TAP) to help control the vertical dimension. This study aimed to evaluate its efficiency by measuring the tongue resting pressure at different anteroposterior positions of the TAP in the upright and supine positions and to investigate the effect of changes in body position. Our study recruited 17 volunteers with individual normal occlusion (4 males, 13 females, age 22-33 years). An individualised TAP was designed for each subject. With a miniature sensor (FSS1500NS) installed in the device, we measured the pressure at the level of the distal second premolar (PM2), the first molar (M1) and the second molar (M2) in both the upright and supine positions. Nonparametric analysis was applied with the level of significance set at 0.05. In the upright position, tongue pressures obtained at PM2, M1 and M2 were 183.94, 130.81 and 113.07 Pa, respectively, with the maximum value detected at PM2 (P = 0.001). While in the supine position, pressures of 187.03, 156.87 and 201.69 Pa were detected at the same sites, with significantly higher values for M1 (P = 0.002) and M2 (P = 0.004). Tongue resting pressure decreases from the anterior aspect to the posterior aspect in the upright position. In the supine position, the pressure is consistent across the midline with pressure enhancement at M1 and M2. As many questions remain about this appliance and appropriate intruding force, further clinical and basic studies are required prior to its clinical implementation.

  18. Anchorage of mature conifers: resistive turning moment, root-soil plate geometry and root growth orientation.

    Science.gov (United States)

    Lundström, Tor; Jonas, Tobias; Stöckli, Veronika; Ammann, Walter

    2007-09-01

    Eighty-four mature Norway spruce (Picea abies L. Karst), silver fir (Abies alba Mill) and Scots pine (Pinus sylvestris L.) trees were winched over to determine the maximum resistive turning moment (M(a)) of the root-soil system, the root-soil plate geometry, the azimuthal orientation of root growth, and the occurrence of root rot. The calculation of M(a), based on digital image tracking of stem deflection, accounted not only for the force application and its changing geometry, but also for the weight of the overhanging tree, representing up to 42% of M(a). Root rot reduced M(a) significantly and was detected in 25% of the Norway spruce and 5% of the silver fir trees. Excluding trees with root rot, differences in M(a) between species were small and insignificant. About 75% of the variance in M(a) could be explained by one of the four variables--tree mass, stem mass, stem diameter at breast height squared times tree height, and stem diameter at breast height squared. Among the seven allometric variables assessed above ground, stem diameter at breast height best described the root-soil plate dimensions, but the correlations were weak and the differences between species were insignificant. The shape of the root-soil plate was well described by a depth-dependent taper model with an elliptical cross section. Roots displayed a preferred azimuthal orientation of growth in the axis of prevailing winds, and the direction of frequent weak winds matched the orientation of growth better than that of rare strong winds. The lack of difference in anchorage parameters among species probably reflects the similar belowground growth conditions of the mature trees.

  19. Preliminary assessment report for Camp Carroll Training Center, Installation 02045, Anchorage, Alaska. Installation Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Krokosz, M.; Sefano, J.

    1993-08-01

    This report presents the results of the preliminary assessment (PA) conducted by Argonne National Laboratory at the Alaska Army National Guard property known as Camp Carroll Training Center, located on the Fort Richardson Army facility near Anchorage, Alaska. Preliminary assessments of federal facilities are being conducted to compile the information necessary for the completion of preremedial activities and to provide a basis for establishing, corrective actions in response to releases of hazardous substances. The principal objective of the PA is to characterize the site accurately and determine the need for further action by examining site activities, types and quantities of hazardous substances used, the nature and amounts of wastes generated or stored at the facility, and potential pathways by which contamination could affect public health and the environment. The primary environmentally significant operations (ESOs) associated with the property are (1) the Alaska Air National Guard storage area behind Building S57112 (Organizational Maintenance Shop [OMS] 6); (2) the state of Alaska maintenance facility and the soil/tar-type spill north of the state of Alaska maintenance facility; (3) the waste storage area adjacent to OMS 6; (4) the contaminated area from leaking underground storage tanks (USTs) and the oil-water separator; and (5) soil staining in the parking area at the Camp Carroll Headquarters Building. Camp Carroll appears to be in excellent condition from an environmental standpoint, and current practices are satisfactory. Argonne recommends that the Alaska Department of Military Affairs consider remediation of soil contamination associated with all storage areas, as well as reviewing the practices of other residents of the facility. Argonne also recommends that the current methods of storing waste material behind Building S57112 (OMS 6) be reviewed for alternatives.

  20. Optimization Design of Anchorage Structure for Safety Belt on Rear Floor%后地板安全带固定点结构优化设计

    Institute of Scientific and Technical Information of China (English)

    闻培培; 李宏华; 赵福全

    2012-01-01

    针对后地板安全带固定点的3种结构形式,对后地板安全带固定点相关法规进行了介绍,并对后排安全带固定点的强度进行了分析.通过分析某车型后地板安全带固定点强度失效原因,对其后地板安全带固定点结构和焊点进行了优化,优化后的结构在模具冲压和车身焊接中均未出现问题,满足了静拉试验相关法规要求.%The three structural types of anchorage point of safety belt on rear floor and the regulations of anchorage point of rear safety belts are introduced in this paper, and the strength of rear seat belt anchorage point is analyzed. By analyzing cause of failure of seat belt anchorage of rear floor of a vehicle model, optimization is made to seat belt anchorage structure and welding point of its rear floor, the optimized structure does not fail either in die stamping nor body welding, and related regulation requirement of static tensile test is thus satisfied.

  1. Intrusão dentária utilizando mini-implantes Orthodontic intrusion with mini-implant anchorage

    Directory of Open Access Journals (Sweden)

    Telma Martins de Araújo

    2008-10-01

    Full Text Available INTRODUÇÃO: dentre os diversos tipos de movimentos dentários induzidos ortodonticamente, o de intrusão é, sem dúvida, um dos mais difíceis de serem conseguidos. A mecânica intrusiva convencional, apesar de viável, é complexa, no que diz respeito ao controle de seus efeitos colaterais. Isso, em grande parte, refere-se à dificuldade em se obter uma ancoragem satisfatória. Neste contexto, os mini-implantes, por oferecerem efetiva ancoragem esquelética, têm se mostrado de extrema valia para os ortodontistas, tornando a intrusão, tanto de dentes anteriores quanto posteriores, um procedimento cada vez mais simples, do ponto de vista mecânico. OBJETIVO: pretende-se, então, neste artigo, descrever e demonstrar, clinicamente, as diversas possibilidades de utilização dos mini-implantes como recurso de ancoragem para o movimento de intrusão.INTRODUCTION: Among all different varieties of orthodontically induced tooth movement, intrusion is, without doubt, one of the most difficult movements to be reached. Conventional intrusive biomechanics, although possible, may lead to undesirable side-effects. These events, in most cases, are related to the difficulty in obtaining an efficient anchorage unit. Then, mini-implants, because of their high success rates of effective skeletal anchorage, are valuable devices to orthodontists, transforming the intrusion movement, both at the anterior and the posterior regions, a more and more uncomplicated biomechanical procedure. AIM: to describe and show, clinically, different ways of using mini-implants as an anchorage system to intrusion movement.

  2. Study on Fatigue Behavior of Anchorage of Cable and Girder of Long Span Cable-Stayed Bridge

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A full scale model test is done and a FEM model is established toinvestigate the fatigue behavior of the Nancha cable-stayed bridge of the Nanjing Second Yangtz River Bridge, a long span steel bridge with a main span of 628 m. The results of test and FEM are analyzed and compared. It is shown that they are in good agreement. It is verified that the fatigue characteristic of the anchorage structure of cable and girder of the bridge satisfies the requirements specified by Chinese, British and American codes.

  3. Combined maxillary and mandibular midline and mandibular ramus distraction osteogenesis for treatment of a Class II patient with implants as orthodontic anchorage.

    Science.gov (United States)

    Takahashi, Ichiro; Kawamura, Hiroshi; Takano-Yamamoto, Teruko

    2010-03-01

    This case report describes the treatment of a woman with severe mandibular retrusion and maxillomandibular transverse deficiency. Her malocclusion was characterized by a large overjet, a deep overbite, and a V-shaped dental arch, and she had a skeletal Class II profile. Treatement included combined maxillary and mandibular midline expansion, maxillary downward repositioning, and mandibular ramus lengthening with distraction osteogenesis with implants as orthodontic anchorage. During the postdistraction orthodontic treatment period, some skeletal relapse occurred. Implants provided absolute orthodontic anchorage to overcome the unexpected skeletal changes. Combined orthodontic treatment with implants for anchorage and distraction osteogenesis successfully expanded the maxilla and the mandible and corrected the mandibular deficiency. Two-year follow-up records show a morphologically and functionally stable result.

  4. 种植体支抗在正畸临床上的应用%Implant Anchorage in Orthodontic Clinical Application

    Institute of Scientific and Technical Information of China (English)

    刘丽梅

    2015-01-01

    目的:探讨种植体支抗在正畸临床治疗。方法对20例种植体支抗的正畸治疗应用方法及临床应用体会。结果20例种植体支抗,微镙钉种植16例,钛板种植体3例,修复种植体1例。种植体均保持了稳定,种植体周围软组织健康,脱落率10%。结论牙齿的缺失造成支抗的不足,某些类型的牙齿移动难以或不能完成。将钛合金牙种植体作为支抗完成正畸治疗,正畸治疗结束后,将种植体行永久性修复。%Objective To investigate the implant anchorage in orthodontic clinical treatment. Methods 20 cases of implant anchorage orthodontic treatment application methods and clinical application experience. Results 20 cases of implant anchorage, micro screws planting 16 cases, 3 cases of titanium implants , implant restoration one case . Implants have maintained a stable implant soft tissue health, loss rate of 10%. Conclusion The lack of teeth caused by lack of anchorage, and certain types of tooth movement difficult or impossible to complete. The titanium dental implants as orthodontic anchorage is completed, after the end of orthodontic treatment, the implant permanently repair the line, traditional dental implant anchorage to be more widely used in orthodontic patients with a combination therapy of implant restoration.

  5. Bst1 is required for Candida albicans infecting host via facilitating cell wall anchorage of Glycosylphosphatidyl inositol anchored proteins

    Science.gov (United States)

    Liu, Wei; Zou, Zui; Huang, Xin; Shen, Hui; He, Li Juan; Chen, Si Min; Li, Li Ping; Yan, Lan; Zhang, Shi Qun; Zhang, Jun Dong; Xu, Zheng; Xu, Guo Tong; An, Mao Mao; Jiang, Yuan Ying

    2016-01-01

    Glycosylphosphatidyl inositol anchored proteins (GPI-APs) on fungal cell wall are essential for invasive infections. While the function of inositol deacylation of GPI-APs in mammalian cells has been previously characterized the impact of inositol deacylation in fungi and implications to host infection remains largely unexplored. Herein we describe our identification of BST1, an inositol deacylase of GPI-Aps in Candida albicans, was critical for GPI-APs cell wall attachment and host infection. BST1-deficient C. albicans (bst1Δ/Δ) was associated with severely impaired cell wall anchorage of GPI-APs and subsequen unmasked β-(1,3)-glucan. Consistent with the aberrant cell wall structures, bst1Δ/Δ strain did not display an invasive ability and could be recognized more efficiently by host immune systems. Moreover, BST1 null mutants or those expressing Bst1 variants did not display inositol deacylation activity and exhibited severely attenuated virulence and reduced organic colonization in a murine systemic candidiasis model. Thus, Bst1 can facilitate cell wall anchorage of GPI-APs in C. albicans by inositol deacylation, and is critical for host invasion and immune escape. PMID:27708385

  6. Remains of the ancient ports and anchorage points at Miyani and Visawada, on the west coast of India: A study based on underwater investigations

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh; Tripati, S.

    as an excellent natural harbour. The important antiquities include varieties of stone anchors, which are very similar to those reported from Dwarka and Bet Dwarka. The identification of ancient anchorage points between water depth of 5 and 15 m is another...

  7. Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2

    NARCIS (Netherlands)

    Vormer, Tinke L; Foijer, Floris; Wielders, Camiel L C; te Riele, Hein

    2008-01-01

    Mouse embryonic fibroblasts (MEFs) deficient for pocket proteins (i.e., pRB/p107-, pRB/p130-, or pRB/p107/p130-deficient MEFs) have lost proper G(1) control and are refractory to Ras(V12)-induced senescence. However, pocket protein-deficient MEFs expressing Ras(V12) were unable to exhibit anchorage-

  8. Anchorage of TiO2-blasted, HA-coated, and machined implants: an experimental study with rabbits

    DEFF Research Database (Denmark)

    Gotfredsen, K; Wennerberg, A; Johansson, C

    1995-01-01

    The purpose of this study was to evaluate the histometrical and biomechanical anchorage of TiO2-blasted implants and TiO2-blasted implants coated with hydroxyapatite. The control implants were machined. Twenty-six rabbits had a total of 156 implants placed in the proximal part of the tibia. Each...... rabbit had a machined, a TiO2-blasted, and a TiO2-blasted, HA-coated implant placed in each tibia. After a healing period of 3 and 12 weeks, respectively, the implants placed in the right tibia were used for removal torque test, and the implants placed in the left tibia were used for histomorphometrical...... measurements. Preoperatively, implants from the same batches were examined topographically with a TopScan 3D system. The TiO2-blasted implants demonstrated significantly higher removal torque values than the machined implants, and they also had a significantly more irregular surface. Furthermore, significantly...

  9. [Low-cost simple anchorage systems in the removable hybrid prosthesis. Locator Root Attachment and Würzburg post].

    Science.gov (United States)

    Teubner, Eckart; Galindo, Martha L; Arnold, Dario; Marinello, Carlo P

    2009-01-01

    For a simple and provisional retention of a removable prosthesis, less expensive direct retainers are an option compared to indirect cast gold copings with attachment. The Dalbo-Rotex-retainer and the Ticap-system are clinically established. The Locator Root attachment and the Würzburger Stift were recently introduced. The Locator Root attachment uses a massive profiled cylindrical post as a radicular anchorage. The Würzburger Stift has a small endodontic part which is retained by four spreadable lamellae in a convergent cavity. They further differ in the design of the male and female part. Depending on the clinical situation these characteristics can offer benefits and disadvantages. Both systems are documented and their indication, advantages and restrictions are discussed with clinical relevance.

  10. Recombinant differential anchorage probes that tower over the spatial dimension of intracellular signals for high content screening and analysis.

    Science.gov (United States)

    Schembri, Laura; Zanese, Marion; Depierre-Plinet, Gaelle; Petit, Muriel; Elkaoukabi-Chaibi, Assia; Tauzin, Loic; Florean, Cristina; Lartigue, Lydia; Medina, Chantal; Rey, Christophe; Belloc, Francis; Reiffers, Josy; Ichas, François; De Giorgi, Francesca

    2009-12-01

    Recombinant fluorescent probes allow the detection of molecular events inside living cells. Many of them exploit the intracellular space to provide positional signals and, thus, require detection by single cell imaging. We describe here a novel strategy based on probes capable of encoding the spatial dimension of intracellular signals into "all-or-none" fluorescence intensity changes (differential anchorage probes, DAPs). The resulting signals can be acquired in single cells at high throughput by automated flow cytometry, (i) bypassing image acquisition and analysis, (ii) providing a direct quantitative readout, and (iii) allowing the exploration of large experimental series. We illustrate our purpose with DAPs for Bax and the effector caspases 3 and 7, which are keys players in apoptotic cell death, and show applications in basic research, high content multiplexed library screening, compound characterization, and drug profiling.

  11. A Study of the system control model of caisson dewatering of the north anchorage of Taizhou Bridge

    Institute of Scientific and Technical Information of China (English)

    Zhao Yanrong; Zhou Zhifang; Ruan Jing

    2011-01-01

    A caisson foundation is applied to the north anchorage of Taizhou Yangtze River Highway Bridge of which the initial caisson sinking requires dewatering. Since the caisson foundation is quite close to nearby buildings, a system control model is established with source (sink) distribution and intensity being the object function, minimum requirements of settlement and deformation of surroundings caused by dewatering and dynamic water levels during different working procedures being constraints, and the design parameter of pumping wells being the variable, so as to lower the jeopardizing of surrounding buildings, which provides a new method for active control over settlement during dewatering. Such a method of dewatering based on system control model should be of significance for similar projects involving dewatering.

  12. Effect of molar intrusion with temporary anchorage devices in patients with anterior open bite: a systematic review

    Directory of Open Access Journals (Sweden)

    Ahmad Saleem Alsafadi

    2016-03-01

    Full Text Available Abstract Objective The objective of the study is to assess the effect of molar intrusion with temporary anchorage devices on the vertical facial morphology and mandibular rotation during open bite treatment in the permanent dentition. Methods We performed a systematic review of the published data in seven electronic databases up to September 2015. We considered studies for inclusion if they were examining the effects of posterior teeth intrusion on the vertical facial morphology with open bite malocclusion in the permanent dentition. Study selection, risk of bias assessment, and data-extraction were performed in duplicate. Meta-analysis was not possible due to dissimilarity and heterogeneity among the included studies. Results Out of the 42 articles that met the initial eligibility criteria, 12 studies were finally selected. Low level of scientific evidence was identified after risk of bias assessment of the included studies with no relevant randomized controlled trial performed. Out of the 12 selected studies, five studies used miniplates and seven studies used miniscrews. Mandibular counterclockwise rotation was found to be between 2.3° and 3.9° in six studies (as sassed by mandibular plane angle, between MeGo or GoGn and SN or FH plane while it was less than 2° in the remaining studies. Conclusions Current weak evidence suggests that molar intrusion with temporary anchorage devices may cause mandibular counterclockwise autorotation. Future well-conducted and clearly reported multicenter randomized controlled trials that include a non-treatment control group are needed to make robust recommendations regarding the amount of mandibular rotation during open bite treatments.

  13. Analysis of Vehicle Seat Belt Anchorage Strength%汽车安全带固定点强度分析

    Institute of Scientific and Technical Information of China (English)

    邓国红; 杨浩; 杨鄂川; 张勇

    2011-01-01

    To analyze the vehicle seat belt anchorage strength, the finite element model of body-in- white, seats, seat belts and the body module (hip block, shoulder block cessing software Hypermesh, the explicit solution method in LS-DYNA ) is is established by pre-pro- used, the specified load condition is set according to the national standard, an accurate prediction is made on whether the structure can meet the standard, a method which uses the FEM to analyze the seat belt anchorage strength is found. This method can be extended to other quasi-static strength analysis problems, and analyze the model which is larger and more difficuh to calculate using the implicit integration, which has a strong practicality in product development.%为了进行汽车安全带固定点强度分析,运用有限元分析软件Hypermesh建立白车身、座椅、安全带、人体模块(臀块和肩块)有限元模型。采用LS-DYNA的显式求解模块,按照国家标准设置规定的载荷,分析结构通过标准的可能性。验证了运用有限元显式积分分析汽车安全带固定点强度的方法。该方法可推广到其他准静态强度分析中,用于分析那些比较大的、隐式积分计算比较困难的模型。

  14. Characterization of the aspects of osteoprogenitor cell interactions with physical tetracalcium phosphate anchorage on titanium implant surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Chia-Ling [Advanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan (China); Dental Medical Devices and Materials Research Center, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan (China); Chang, Ya-Yuan; Liou, Cian-Hua [Alliance Global Technology Co., Ltd., Kaohsiung Medical Device Special Zone in Southern Taiwan Science Park, Kaohsiung 82151, Taiwan (China); Chen, Wen-Cheng, E-mail: wencchen@fcu.edu.tw [Advanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan (China)

    2015-04-01

    Well-designed implants are used not only to modify the geometry of the implant but also to change the chemical properties of its surfaces. The present study aims to assess the biofunctional effects of tetracalcium phosphate (TTCP) particles as a physical anchor on the implant surface derived through sandblasting. The characteristics of the surface, cell viability, and alkaline phosphatase (ALP) activity toward osteoprogenitor cells (D1) were obtained. D1 cells were cultured on a plain surface that underwent sandblasting and acid etching (SLA) (control SLA group) and on different SLA surfaces with different anchoring TTCP rates (new test groups, M and H). The mean anchoring rates were 57% (M) and 74% (H), and the anchored thickness was estimated to range from 12.6 μm to 18.3 μm. Compared with the control SLA surface on Ti substrate, the new test groups with different TTCP anchoring rates (M and H) failed to improve cell proliferation significantly but had a well-differentiated D1 cell phenotype that enhanced ALP expression in the early stage of cell cultures, specifically, at day 7. Results suggest that the SLA surface with anchored TTCP can accelerate progenitor bone cell mineralization. This study shows the potential clinical application of the constructed geometry in TTCP anchorage on Ti for dental implant surface modification. - Highlights: • TTCP (tetracalcium phosphate) as a physical anchorage on implant is characterized. • Theoretical values of anchored thickness and capping areas were estimated. • TTCP anchored by sandblasting can accelerate progenitor bone cell mineralization. • TTCP anchored on SLA (sandblasting and acid etching) surface is a promising method.

  15. Mechanical behavior experiment of wedge-bond anchorage for CFRP-tendons%CFRP筋复合型锚具的受力性能试验

    Institute of Scientific and Technical Information of China (English)

    王军; 李明君; 蔡东升; 刘德鑫

    2012-01-01

    In order to investigate the influence of main design parameters on anchorage performance and internal stress distribution of wedge-bond anchorage for CFRP tendons, five groups of parameter tests on wedge-bond anchorage were designed. The ultimate load, slip deformation of anchor ring and stress of metal sleeve stations were determined. The influence of design parameters on anchorage performance, the tress distribution and variation of metal sleeve were contrastively investigated through static loading testing. The results show that the anchorage performance with metal sleeve thickness of 2 mm, a wedge length of 65 mm, bond length of 500 mm is optimal. The anchor between wedge and metal sleeve is good without relative displacement. The tress distribution and variation of metal sleeve can reflect the internal stress distribution of anchorage, and the perk of stress curve indicates bonding failure between colloid and CFRP tendon near the observation point.%为研究CFRP筋复合型锚具的主要设计参数对锚固性能的影响及锚具内部受力情况,设计了5个复合型锚具的参数静载试验,测量了锚具的极限荷载、锚环-CFRP筋间滑移变形和金属筒测点应变,通过静载试验对比分析了各设计参数对锚固效果的影响,以及金属筒表面应力的分布情况与变化规律.研究结果表明:当金属筒壁厚为2 mm,夹片夹持长度为65 mm,粘结长度为500 mm时,锚具的锚固性能较好;夹片-金属筒间锚固良好,无滑移;金属筒应力分布与变化可反映锚具内部受力情况,测点应力曲线峰值预示该位置附近的胶体与CFRP筋间的粘结破坏.

  16. Leucine zipper structure of TSC-22 (TGF-beta stimulated clone-22) markedly inhibits the anchorage-independent growth of salivary gland cancer cells.

    Science.gov (United States)

    Hino, Satoshi; Kawamata, Hitoshi; Omotehara, Fumie; Uchida, Daisuke; Begum, Nasima-Mila; Yoshida, Hideo; Sato, Mitsunobu; Fujimori, Takahiro

    2002-01-01

    Several investigators have demonstrated that TGF-beta stimulated clone-22 (TSC-22) regulates cell growth and differentiation, and cell death. TSC-22 is a putative transcriptional regulator containing a leucine zipper-like structure and a nuclear export signal. We previously showed the cytoplasmic localization of TSC-22 and the nuclear translocation of TSC-22 concomitant with induction of apoptosis in salivary gland cancer cells. In the present study, we attempted to identify the active domain of TSC-22 protein that regulated the biological functions of TSC-22. We constructed three mammalian expression vectors, which could produce full length TSC-22 only in cytoplasm, the leucine zipper structure of TSC-22 in both cytoplasm and nucleus, and the leucine zipper structure only in nucleus. Then, we transfected a salivary gland cancer cell line, HSG with these expression vectors, and investigated the growth profile of the transfectants. None of the TSC-22 constructs inhibited the monolayer growth and the anchorage-dependent colony formation of HSG cells. However, the leucine zipper structure of TSC-22 markedly inhibited the anchorage-independent colony formation of HSG cells (pway ANOVA). Full length TSC-22 also suppressed the anchorage-independent colony formation of HSG cells, although the effect of full length TSC-22 was much lower than those of the leucine zipper constructs. These observations suggest that the leucine zipper structure in TSC-22 protein is an active domain that negatively regulates the growth of salivary gland cancer cells.

  17. Changes in strain patterns after implantation of a short stem with metaphyseal anchorage compared to a standard stem: an experimental study in synthetic bone

    Directory of Open Access Journals (Sweden)

    Jens Gronewold

    2014-03-01

    Full Text Available Short stem hip arthroplasties with predominantly metaphyseal fixation, such as the METHA® stem (Aesculap, Tuttlingen, Germany, are recommended because they are presumed to allow a more physiologic load transfer and thus a reduction of stress-shielding. However, the hypothesized metaphyseal anchorage associated with the aforementioned benefits still needs to be verified. Therefore, the METHA short stem and the Bicontact® standard stem (Aesculap, Tuttlingen, Germany were tested biomechanically in synthetic femora while strain gauges monitored their corresponding strain patterns. For the METHA stem, the strains in all tested locations including the region of the calcar (87% of the non-implanted femur were similar to conditions of synthetic bone without implanted stem. The Bicontact stem showed approximately the level of strain of the non-implanted femur on the lateral and medial aspect in the proximal diaphysis of the femur. On the anterior and posterior aspect of the proximal metaphysis the strains reached averages of 78% and 87% of the non-implanted femur, respectively. This study revealed primary metaphyseal anchorage of the METHA short stem, as opposed to a metaphyseal-diaphyseal anchorage of the Bicontact stem.

  18. Chlamydia induces anchorage independence in 3T3 cells and detrimental cytological defects in an infection model.

    Directory of Open Access Journals (Sweden)

    Andrea E Knowlton

    Full Text Available Chlamydia are gram negative, obligate intracellular bacterial organisms with different species causing a multitude of infections in both humans and animals. Chlamydia trachomatis is the causative agent of the sexually transmitted infection (STI Chlamydia, the most commonly acquired bacterial STI in the United States. Chlamydial infections have also been epidemiologically linked to cervical cancer in women co-infected with the human papillomavirus (HPV. We have previously shown chlamydial infection results in centrosome amplification and multipolar spindle formation leading to chromosomal instability. Many studies indicate that centrosome abnormalities, spindle defects, and chromosome segregation errors can lead to cell transformation. We hypothesize that the presence of these defects within infected dividing cells identifies a possible mechanism for Chlamydia as a cofactor in cervical cancer formation. Here we demonstrate that infection with Chlamydia trachomatis is able to transform 3T3 cells in soft agar resulting in anchorage independence and increased colony formation. Additionally, we show for the first time Chlamydia infects actively replicating cells in vivo. Infection of mice with Chlamydia results in significantly increased cell proliferation within the cervix, and in evidence of cervical dysplasia. Confocal examination of these infected tissues also revealed elements of chlamydial induced chromosome instability. These results contribute to a growing body of data implicating a role for Chlamydia in cervical cancer development and suggest a possible molecular mechanism for this effect.

  19. On-site tests to estimate aquifer permeability of drainage area of south caisson anchorage construction of Taizhou Bridge

    Institute of Scientific and Technical Information of China (English)

    Feng Zhaoxiang; Zhao Yanrong

    2011-01-01

    During the construction of the south caisson anchorage of Taizhou Bridge, the drainage area is located in the lower reaches of the Yangtze River and the permeability of stratums there is considerable. In order to maintain progress and guarantee safety during the sinking of the caisson, water should be drained in the initial period. Subsequently, detailed information about the aquifer permeability is required to make sure that the drainage will proceed successfully,which consequently necessitates the on-site estimation of the aquifer permeability in the drainage area. Therefore, the traditional pumping test and slug test are implemented respectively on site. The comparison of computational results of these two tests indicates that they are consistent overall. Notwithstanding, as slug test can be conducted with portable facilities in a short time and the manipulation is easy and few people need to be involved, the advantages of slug test is conspicuous compared with the traditional pumping test. It could be speculated that slug test will gain a prevalent application in the measurement of aquifer permeability in the future.

  20. fau and its ubiquitin-like domain (FUBI) transforms human osteogenic sarcoma (HOS) cells to anchorage-independence.

    Science.gov (United States)

    Rossman, Toby G; Visalli, Melissa A; Komissarova, Elena V

    2003-03-27

    Arsenite is the most likely carcinogenic form of arsenic in the environment. Previously, expression cloning for cDNAs whose overexpression confers arsenite-resistance in Chinese hamster V79 cells identified two genes: fau and a novel gene, asr2. The fau gene encodes a ubiquitin-like protein (here called FUBI) fused to the ribosomal S30 protein. Since the expression of the fox sequence (antisense to fau) increased the tumorigenicity of a mouse sarcoma virus, it was proposed that fau might be a tumor suppressor gene. We intended to test its ability to block arsenite-induced transformation of human osteogenic sarcoma (HOS) cells to anchorage-independence. Instead, we found that overexpressing fau itself was able to transform HOS cells. When the two domains were expressed separately, only FUBI was transforming and only the S30 domain conferred arsenite resistance. An incidental finding was the transforming activity of the selectable marker, hyg. FUBI belongs to the ubiquitin-like protein group that is capable of forming conjugates to other proteins, although none have so far been identified. Alternatively, FUBI may act as a substitute or inhibitor of ubiquitin, to which it is most closely related, or to close ubiquitin-like relatives UCRP, FAT10, and/or Nedd8.

  1. Improved bone anchorage of hydroxypatite coated implants compared with tricalcium-phosphate coated implants in trabecular bone in dogs.

    Science.gov (United States)

    Lind, M; Overgaard, S; Bünger, C; Søballe, K

    1999-05-01

    Tricalcium phosphate (TCP) and hydroxyapatite (HA) ceramic coatings are bioactive coatings that have been shown to stimulate bone apposition onto ceramic-coated implants. TCP and HA ceramics have well-documented differences in physical properties, but both types of ceramics are used for stimulation of bone ongrowth to cementless endo-prosthetic components clinically. However, little is known about the difference in osteoconductive properties between these coatings when inserted into trabecular bone in a controlled experimental situation. Unloaded cylindrical gritblasted titanium (Ti-6A1-4V) implants (6 x 10 mm) coated with either hydroxyapatite (HA) or tricalcium phosphate (TCP) ceramic were inserted into the proximal humerus of 20 skeletally mature dogs. The implants were initially surrounded by a 2 mm gap. Each animal received one HA-coated implant and one TCP-coated implant. All dogs were sacrificed 6 weeks after surgery. Results were evaluated by histomorphometry and mechanical push-out test. Push-out tests demonstrated that HA-coated implants were 10-fold stronger fixated in comparison to TCP-coated implant. Bone ongrowth was significantly higher for HA-coated implants compared to TCP-coated implants. Bone volume in the gap showed a tendency to less bone volume around HA-coated implants compared to TCP-coated implants but this difference was insignificant. As expected almost all of the TCP coating were resorbed after 6 weeks and almost none of the HA coating. HA-coated implants with a grit-blasted surface provide a favorable early mechanical implant anchorage most likely due to superior ceramic stability compared to TCP-coated implants.

  2. CD45/CD11b Positive Subsets of Adult Lung Anchorage-Independent Cells Harness Epithelial Stem Cells

    Science.gov (United States)

    Peter, Yakov; Sen, Namita; Levantini, Elena; Keller, Steven; Ingenito, Edward P; Ciner, Aaron; Sackstein, Robert; Shapiro, Steven D

    2015-01-01

    Compensatory growth is mediated by multiple cell types that interact during organ repair. To elucidate the relationship between the stem/progenitor cells that proliferate or differentiate and the somatic cells of lung, we utilized a novel ex vivo pneumoexplant system. Applying this technique, we identified a sustained culture of repopulating adult progenitors in the form of free floating anchorage-independent cells (AICs). AICs did not express integrin proteins α5, β3, and β7, and constituted 37% of the total culture at day 14, yielding a mixed yet conserved population that recapitulated RNA expression patterns of the healthy lung. AICs exhibited rapid proliferation manifested by a marked 60-fold increase in cell numbers by day 21. Over 50% of the AIC population was cKit+ or double-positive for CD45+ and CD11b+ antigenic determinants, consistent with cells of hematopoietic origin. The latter subset was found to be enriched with prosurfactant protein-C and SCGB1A1 expressing putative stem cells and with aquaporin-5 producing cells, characteristic of terminally differentiated alveolar epithelial type-1 pneumocytes. AICs undergo remodeling to form a cellular lining at the air/gel interface, and TGFβ1 treatment modifies protein expression, implying direct-differentiation of this population. These data confirm the active participation of clonogenic hematopietic stem cells in a mammalian model of lung repair and validate mixed stem/somatic cell cultures, which embrace sustained cell viability, proliferation, and differentiation, for use in studies of compensatory pulmonary growth. PMID:22585451

  3. SHEAR LAG-DEBONDING MODEL FOR ANCHORAGE SECTION OF PRESTRESSED ANCHOR CABLE%预应力锚索锚固段的剪滞-脱黏模型

    Institute of Scientific and Technical Information of China (English)

    尤春安; 战玉宝; 刘秋媛; 孙琳琳; 王开彬

    2013-01-01

    Based on the calculating pattern of pulling prestressed anchorage body out from the base,the anchorage section can be divided into elastic region,plastic slide region and debonding region after analyzing the deformation and the damage process of the interface layer between anchorage body and grouting material,and the interfacial layer model for anchorage body and rock and soil mass is established.The theoretical solution of interfacial stress distribution was deduced by adopting the flow rule which associates with Coulomb condition.At the same time,a kind of new interface element model with properties of dilatancy and slippage is constructed; and interfacial stress distribution is calculated by two ways of numerical simulation and theoretical solution to verify the correctness of each other,so as to provide a new theoretical basis to calculate,analyze and design anchorage bodies.The results indicate that the main mechanical region is plastic slide region.So the plastic slippage state is the main state which the anchorage body usually in,so our researching and designing should be based on this state.In order to improve the anchoring force,we should improve maximum shear stress and extend the range of slip regime before the slip regime entering the debonding state.%基于预应力锚索锚固体从岩土体中拔出计算模式,通过锚固体与灌浆材料的界面界面层变形-破坏过程分析,将锚固段分为弹性区、塑性滑移区和脱黏区,建立锚固体-岩土体界面力学模型,采用与Coulomb条件关连的流动法则,导出界面应力分布的理论解;同时,构造具有剪胀和滑移特性的新型有限元界面单元,采用数值模拟的方法与界面应力分布的理论解进行相互验证,为锚固体受力的计算、分析与锚固体的设计提供理论依据.分析表明,锚固体的弹性区和脱黏区的受力较小,主要受力部分是塑性滑移区.因此,锚固体荷载的主要工况是塑性滑移状态,在研究

  4. Elevated p21-Activated Kinase 2 Activity Results in Anchorage-Independent Growth and Resistance to Anticancer Drug–Induced Cell Death

    Directory of Open Access Journals (Sweden)

    Jerry W. Marlin

    2009-03-01

    Full Text Available p21-Activated kinase 2 (PAK-2 seems to be a regulatory switch between cell survival and cell death signaling. We have shown previously that activation of full-length PAK-2 by Rac or Cdc42 stimulates cell survival, whereas caspase activation of PAK-2 to the proapoptotic PAK-2p34 fragment is involved in the cell death response. In this study, we present a role of elevated activity of full-length PAK-2 in anchorage-independent growth and resistance to anticancer drug–induced apoptosis of cancer cells. Hs578T human breast cancer cells that have low levels of PAK-2 activity were more sensitive to anticancer drug–induced apoptosis and showed higher levels of caspase activation of PAK-2 than MDA-MB435 and MCF-7 human breast cancer cells that have high levels of PAK-2 activity. To examine the role of elevated PAK-2 activity in breast cancer, we have introduced a conditionally active PAK-2 into Hs578T human breast cells. Conditional activation of PAK-2 causes loss of contact inhibition and anchorage-independent growth of Hs578T cells. Furthermore, conditional activation of PAK-2 suppresses activation of caspase 3, caspase activation of PAK-2, and apoptosis of Hs578T cells in response to the anticancer drug cisplatin. Our data suggest a novel mechanism by which full-length PAK-2 activity controls the apoptotic response by regulating levels of activated caspase 3 and thereby its own cleavage to the proapoptotic PAK-2p34 fragment. As a result, elevated PAK-2 activity interrupts the apoptotic response and thereby causes anchorage-independent survival and growth and resistance to anticancer drug–induced apoptosis.

  5. Orthodontic treatment of impacted teeth with implant anchorage%运用微型种植体支抗矫治埋伏阻生牙

    Institute of Scientific and Technical Information of China (English)

    张敏; 张立亚; 刘佳

    2011-01-01

    Objective To investigate effectiveness and efficiency of impacted teeth correction with implant anchorage.Methods Eight impacted teeth in six patients were corrected with implant anchorage after surgical exposure.Tooth mobility and pulp vitality were evaluated.Dental radiographs were taken before and after treatment.Results Good results were obtained and the impacted teeth were erupted within 3 ~ 5 months after orthodontic traction.The pulp of the teeth was vital Conclusions The implant anchorage could be used in the treatment of impacted teeth.%目的 初步分析运用种植支抗牵引埋伏牙的临床效果,探讨正畸治疗中选择种植支抗牵引埋伏牙的适应证及该项治疗的特点.方法 对6例埋伏牙患者的8颗埋伏牙运用种植支抗进行牵引治疗,牵引后对牙齿的松动度、牙髓活力等各项临床指标进行检查,并摄术前术后曲面断层片对牵引效果进行观察.结果 6例患者经3~5个月的牵引后埋伏牙萌出,牙髓活力正常,未发现牙根吸收.与以往的方法相比,运用种植支抗牵引埋伏牙支抗充足,患者不适感降低.结论 运用种植支抗牵引埋伏牙为埋伏牙牵引治疗提供了一种方法选择.

  6. Ankylosed maxillary incisor with severe root resorption treated with a single-tooth dento-osseous osteotomy, vertical alveolar distraction osteogenesis, and mini-implant anchorage.

    Science.gov (United States)

    Senışık, Neslihan Ebru; Koçer, Gülperi; Kaya, Bulem Üreyen

    2014-09-01

    Dentoalveolar ankylosis interferes with the vertical growth of the alveolar process, which can lead to an open bite, an unesthetic smile, and occlusal disharmony. This case report presents a new treatment protocol for an ankylosed tooth with severe root resorption using a combined surgical orthodontic management protocol involving a single-tooth dento-osseous osteotomy and vertical alveolar distraction osteogenesis with intraoral elastics and mini-implant anchorage. After distraction and active orthodontic treatment, the patient's anterior open bite was corrected. A Class I dental relationship was achieved, overjet was decreased, and a normal incisor relationship was obtained.

  7. Thermal Pollution Mathematical Model. Volume 6: Verification of Three-Dimensional Free-Surface Model at Anclote Anchorage. [environment impact of thermal discharges from power plants

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Tuann, S. Y.; Lee, C. R.

    1980-01-01

    The free-surface model presented is for tidal estuaries and coastal regions where ambient tidal forces play an important role in the dispersal of heated water. The model is time dependent, three dimensional, and can handle irregular bottom topography. The vertical stretching coordinate is adopted for better treatment of kinematic condition at the water surface. The results include surface elevation, velocity, and temperature. The model was verified at the Anclote Anchorage site of Florida Power Company. Two data bases at four tidal stages for winter and summer conditions were used to verify the model. Differences between measured and predicted temperatures are on an average of less than 1 C.

  8. Effects of the earthquake of March 27, 1964, on the Eklutna Hydroelectric Project, Anchorage, Alaska, with a section on television examination of earthquake damage to underground communication and electrical systems in Anchorage: Chapter A in The Alaska earthquake, March 27, 1964: effects on transportation, communications, and utilities

    Science.gov (United States)

    Logan, Malcolm H.; with a section on Television Examination of Earthquake Damage to Underground Communication and Electrical Systems in Anchorage by Burton, Lynn R.

    1967-01-01

    The March 27, 1964, Alaska earthquake and its associated aftershocks caused damage requiring several million dollars worth of repair to the Eklwtna Hydroelectric Project, 34 miles northeast of Anchorage. Electric service from the Eklutna powerplant was interrupted during the early phase of the March 27 earthquake, built was restored (intermittently) until May 9,1964, when the plant was closed for inspection and repair. Water for Eklutna project is transported from Eklutna Lake to the powerplant at tidewater on Knik Arm of Cook Inlet by an underwater intake connected to a 4.46-mile tunnel penstock. The primary damage caused by the earthquake was 1at the intake structure in Eklutna Lake. No damage to the power tunnel was observed. The piles-supported powerplant and appurtenant structures, Anchorage and Palmer substations, and the transmission lines suffered minor dammage. Most damage occurred to facilities constructed on un-consolidated sediments and overburden which densified and subsided during the earthquake. Structures built on bedrock experienced little or no damage. Underground communication and electrical systems in Anchorage were examined with a small-diameter television camera to locate damaged areas requiring repair. Most of the damage was concentrated at or near valley slopes. Those parts of the systems within the major slide areas of the city were destroyed.

  9. Treatment of Class II malocclusion with bialveolar protrusion by means of unusual extractions and anchorage mini-implant

    Directory of Open Access Journals (Sweden)

    Jong-Moon Chae

    2012-10-01

    Full Text Available INTRODUCTION: Patients with dental Class II bialveolar protrusion are generally treated by extracting the four first premolars or two first and two second premolars, and retracting the anterior teeth. This case report describes the treatment of an adult patient with bialveolar protrusion, a Class II canine and molar relationship, and lip protrusion. METHODS: In this patient, the maxillary right second molar (1.7 had to be extracted due to extensive caries. To create sufficient space to retract the anterior teeth, the maxillary right posterior teeth were distalized with a maxillary posterior mini-implant (1.2~1.3 mm in diameter, 10 mm long, which was placed into the maxillary tuberosity area and allowed an en masse retraction of the maxillary anterior teeth. RESULTS: Overall, mini-implant can provide anchorage to produce a good facial profile even without additional premolar extraction in cases of dental Class II bialveolar protrusion with the hopeless second molar. CONCLUSION: The total treatment period was 42 months and the results were acceptable for 34 months after debonding.INTRODUÇÃO: os pacientes com Classe II e biprotrusão alveolar são, geralmente, tratados com extração de quatro primeiros pré-molares ou dois primeiros e dois segundos pré-molares, e retração dos dentes anteriores. Este relato de caso descreve o tratamento de um paciente adulto com biprotrusão alveolar, relação de caninos e de molares em Classe II e protrusão labial. MÉTODOS: nesse paciente, o segundo molar superior direito precisou ser extraído devido a cáries extensas. Para criar espaço suficiente para retração dos dentes anteriores, os dentes posterossuperiores direitos foram distalizados com um mini-implante posterossuperior (1,2 ~ 1,3mm de diâmetro, 10mm de comprimento, que foi colocado na área da tuberosidade maxilar e permitiu uma retração em massa dos dentes anteriores. RESULTADOS: em geral, mini-implantes podem fornecer ancoragem para

  10. 口周肌力在下颌支抗控制中的临床应用研究%Clinical application of perioral muscular forces in mandibular anchorage control

    Institute of Scientific and Technical Information of China (English)

    林汤毅; 许衍; 王震东; 李强

    2011-01-01

    目的 探讨口周肌力在下颌支抗控制中的应用.方法 临床上应用多曲不锈钢丝唇挡配合方丝弓固定矫治器对13例恒牙早期轻度牙列拥挤患者进行矫治,分析治疗前后支抗磨牙位置变化,观察支抗丧失情况.结果 利用口周肌力可以对支抗磨牙进行控制,防止支抗丧失.结论 可以在矫治过程中采用多曲唇挡来增强支抗.而且多曲唇挡制作简单,患者戴用舒适、隐蔽,容易获得患者的配合.%Objective To study the application of perioral muscular forces in the mandibular anchorage control in order to search a new approach of increasing the intro-oral anchorage. Methods Thirteen patients with mild crowding in permanent dentition were treated with edgewise appliance and multiloop lip bumper. The movement of anchorage molar in before and after treatment was recorded so as to observe the loss of anchorage. Results The loss of anchorage could be avoided through the application of perioral muscular forces. Conclusions The multiloop lip bumper can be applied to increase anchorage, which is easily fabricated, comfortable and hidden for patients.

  11. Classically activated macrophages promote anchorage-dependent and anchorage-independent clone formation of breast cancer cells%经典激活巨噬细胞促进乳腺癌细胞贴壁和非贴壁克隆形成

    Institute of Scientific and Technical Information of China (English)

    陈静琦; 朱必胜; 侯开连

    2013-01-01

    目的 探讨经典激活巨噬细胞(M1)对乳腺癌细胞贴壁和非贴壁克隆形成的影响,进一步阐明M1促乳腺癌进展的作用.方法 用密度梯度离心法,从健康成人外周血中分离单个核细胞,体外诱导M1.在乳腺癌细胞与巨噬细胞的无血清共培养体系中,做平板克隆实验;在M1-乳腺癌细胞软琼脂培养体系中,做非贴壁克隆形成实验,检测M1对乳腺癌贴壁克隆和非贴壁克隆形成的影响.结果 在M1的作用下,乳腺癌SK-3rd细胞贴壁克隆和非贴壁克隆形成的能力均增强(P<0.001).结论 M1促进乳腺癌细胞贴壁克隆和非贴壁克隆的形成.%Objective To investigate the effect of activated microphages (M1) on the clone formation of breast cancer cells.Methods Mononuclear cells were isolated from peripheral blood of adult normal subjects by density gradient centrifugation,and M1 was induced in vitro.In the serum-free co-culture system of breast cancer cells and macrophages,the fiat cloning assay was performed and in soft agar culture system of Ml-breast cancer cells,anchorage-independent clone formation assay was performed.Results The anchorage-dependent and anchorage-independent clone formation of SK-3rd breast cancer cells was induced by M1 (P < 0.001).Conclusion M1 promotes anchorage-dependent and anchorage-independent clone formation of breast cancer cells.

  12. Di-Ethylhexylphthalate (DEHP Modulates Cell Invasion, Migration and Anchorage Independent Growth through Targeting S100P in LN-229 Glioblastoma Cells

    Directory of Open Access Journals (Sweden)

    Jennifer Nicole Sims

    2014-05-01

    Full Text Available Glioblastoma multiforme (GBM is the most aggressive brain cancer with a median survival of 1–2 years. The treatment of GBM includes surgical resection, radiation and chemotherapy, which minimally extends survival. This poor prognosis necessitates the identification of novel molecular targets associated with glioblastoma. S100P is associated with drug resistance, metastasis, and poor clinical outcomes in many malignancies. The functional role of S100P in glioblastoma has not been fully investigated. In this study, we examined the role of S100P mediating the effects of the environmental contaminant, DEHP, in glioblastoma cells (LN-229 by assessing cell proliferation, apoptosis, anchorage independent growth, cell migration and invasion following DEHP exposure. Silencing S100P and DEHP treatment inhibited LN-229 glioblastoma cell proliferation and induced apoptosis. Anchorage independent growth study revealed significantly decreased colony formation in shS100P cells. We also observed reduced cell migration in cells treated with DEHP following S100P knockdown. Similar results were observed in spheroid formation and expansion. This study is the first to demonstrate the effects of DEHP on glioblastoma cells, and implicates S100P as a potential therapeutic target that may be useful as a drug response biomarker.

  13. A role for Mfb1p in region-specific anchorage of high-functioning mitochondria and lifespan in Saccharomyces cerevisiae.

    Science.gov (United States)

    Pernice, Wolfgang M; Vevea, Jason D; Pon, Liza A

    2016-02-03

    Previous studies indicate that replicative lifespan in daughter cells of Sacchraromyces cerevisiae depends on the preferential inheritance of young, high-functioning mitochondria. We report here that mitochondria are functionally segregated even within single mother cells in S. cerevisiae. A high-functioning population of mitochondria accumulates at the tip of the mother cell distal to the bud. We find that the mitochondrial F-box protein (Mfb1p) localizes to mitochondria in the mother tip and is required for mitochondrial anchorage at that site, independent of the previously identified anchorage protein Num1p. Deletion of MFB1 results in loss of the mother-tip-localized mitochondrial population, defects in mitochondrial function and premature replicative ageing. Inhibiting mitochondrial inheritance to buds, by deletion of MMR1, in mfb1Δ cells restores mitochondrial distribution, promotes mitochondrial function and extends replicative lifespan. Our results identify a mechanism that retains a reservoir of high-functioning mitochondria in mother cells and thereby preserves maternal reproductive capacity.

  14. Clinical research of orthopedic treatment with implant anchorage in orthodontics%种植支抗在口腔正畸治疗中的临床研究

    Institute of Scientific and Technical Information of China (English)

    李茜; 王军

    2011-01-01

    目的:分析研究种植支抗在口腔正畸治疗中的临床应用情况.方法:回顾性分析2009年1月-2010年1月期间在我院治疗的34例需种植义齿修复同时件错合畸形的患者;或者常规支抗缺乏或不理想的错合畸形的成年患者的临床资料.结果:应用Branemark种植体在牙列缺损律错合畸形患者的缺失牙医植入,以此为种植支抗对34例错合畸形患者进行了治疗.34例患者全部顺利完成治疗,而且种植体无明显松动,34例患者经畸形矫正和义齿修复后获得满意效果.结论:种植支抗能够应用于需种植义齿修复同时件错合畸形的患者,且对口颌系统无不良作用,有较好的临床效果.%Objective: To the clinical research of orthopedic treatment with implant anchorage in orthodontics. Methods: A retrospective analysis a-bout clinical data treatment with 34 patients who required implant restoration at the same time pieces of malocclusion patients and lack of conventional anchorage or unsatisfactory malocclusion in January from 2009 to2010 in our hospital. Results! Application of Branemark implants in the dentition defect with malocclusion in patients who missing teeth implants, the 34 patients with malocclusion were treated on this implant. The whole patients completed treatment successfully without implant loosening. Have obtained satisfactory results. Conclusion: implant anchorage can be used to plant the same time pieces of malocclusion patients,and the corresponding jaw system without adverse effects, have better clinical results.

  15. 铁路悬索桥大吨位隧道锚承载性能分析%Analysis on Bearing Performance of Large-tonnage Tunnel-type Anchorage of Railway Suspension Bridge

    Institute of Scientific and Technical Information of China (English)

    江南; 冯君

    2013-01-01

    丽香铁路金沙江大桥是我国首座采用大吨位隧道式锚碇的铁路悬索桥.本文采用三维弹塑性有限元方法对隧道锚的变形机理、承载能力以及围岩稳定状态进行分析.研究结果表明:在正常缆力作用下,锚碇体及周围岩体的位移均处于毫米量级,远小于悬索桥塔顶允许位移;锚碇体整体表现为以前底板为支点,锚碇体后部向上转动和整体向前滑移的变形模式;锚碇体及围岩绝大部分处于三向受压状态,只是在锚碇底端与下部围岩的接触部分,以及顶拱与边墙交界处局部范围内存在拉应力,建议在这些部位采取措施重点加强;基于超载极限分析法计算得到锚碇体的整体抗滑安全系数在9以上.有限元分析结果为铁路悬索桥隧道锚的优化设计提供了理论依据.%The Jinsha River Bridge of the Lijiang-Xianggelila Railway is the first railway suspension bridge with tunnel type anchorages of large tonnage in China.By using the three dimensional elastoplastic finite element method,the deformation mechanism & bearing capacity of the tunnel anchorage and the stability of surrounding rock were analyzed.The results show as follows:Under the action of normal cable forces,the displacements of the anchorage body and surrounding rock are in the millimeter range,which are far less than the allowable displacements of the suspension bridge tower;the deformation mode of the anchorage body includes the back part of the anchorage body turning upward with the front bottom plate as the fulcrum and the whole anchorage body sliding forward; most parts of the anchorage body and surrounding rock are in the triaxial compression state,except that the contact surface between the bottom end of the anchorage body and the under surrounding rock and,the local boundary area between the crown hog and flank wall are subjected to tensile stresses where stressed strengthening is needed;with the overload limit analysis method

  16. 深基坑锚固工程中成孔技术%Bore-making Technique in the Anchorage Project of Deep Foundation Pit

    Institute of Scientific and Technical Information of China (English)

    曾庆辉

    2001-01-01

    Impact Spiral Drilling is a new bore-making techni que. Its usage in the anchorage project of deep foundation ditch can solve the p roblem of drilling in the soft and hard cross stratum. In this article, the auth or specially introduces the structure of impact spiral drill machine and its ope ration techniques.%冲击螺旋钻孔是一种新的成孔工艺,在深基坑的锚固技术中成功地解决了软硬互层、夹杂地层的钻进。本文详细介绍了冲击螺旋钻的构造和成孔操作技术。

  17. Outcomes and stability in patients with anterior open bite and long anterior face height treated with temporary anchorage devices and a maxillary intrusion splint

    Science.gov (United States)

    Scheffler, Nicole R.; Proffit, William R.; Phillips, Ceib

    2015-01-01

    Introduction Temporary skeletal anchorage devices now offer the possibility of closing anterior open bites and decreasing anterior face height by intruding maxillary posterior teeth, but data for treatment outcomes are lacking. This article presents outcomes and posttreatment changes for consecutive patients treated with a standardized technique. Methods The sample included 33 consecutive patients who had intrusion of maxillary posterior teeth with a maxillary occlusal splint and nickel-titanium coil springs to temporary anchorage devices in the zygomatic buttress area, buccal and apical to the maxillary molars. Of this group, 30 had adequate cephalograms available for the period of treatment, 27 had cephalograms including 1-year posttreatment, and 25 had cephalograms from 2 years or longer. Results During splint therapy, the mean molar intrusion was 2.3 mm. The mean decrease in anterior face height was 1.6 mm, less than expected because of a 0.6-mm mean eruption of the mandibular molars. During the postintrusion orthodontics, the mean change in maxillary molar position was a 0.2-mm extrusion, and there was a mean 0.5-mm increase in face height. Positive overbite was maintained in all patients, with a slight elongation (<2 mm) of the incisors contributing to this. During the 1 year of posttreatment retention, the mean changes were a further eruption of 0.5 mm of the maxillary molars, whereas the mandibular molars intruded by 0.6 mm, and there was a small decrease in anterior face height. Changes beyond 1 year posttreatment were small and attributable to growth rather than relapse in tooth positions. Conclusions Intrusion of the maxillary posterior teeth can give satisfactory correction of moderately severe anterior open bites, but 0.5 to 1.5 mm of reeruption of these teeth is likely to occur. Controlling the vertical position of the mandibular molars so that they do not erupt as the maxillary teeth are intruded is important in obtaining a decrease in face height

  18. Conditions of Proper Interaction of Low-Pressure Injection Piles (LIP) with Structure and Soil, Carrying Capacity of Pile Anchorage in Foundation

    Science.gov (United States)

    Pachla, Henryk

    2016-12-01

    The formation of a pile in the existing foundation and soil creates a new foundation construction which has a structure of foundation-pile-soil. This construction must be able to transfer loads from the foundation to the pile and from the pile to the soil. The pile structure has to transfer an imposed load. From the point of view of continuum mechanics determination of the capacity of such a system is preceded by the analysis of contact problem of three contact surfaces. Each of these surfaces is determined by different pairs of materials. The pair which creates a pile anchorage is a material from which the foundation is built (structure of stone and grout, brick and grout, concrete or reinforced concrete and grout. The pile structure is formed by grout and steel rebar. The pile formed in soil is created by a pair of grout and soil. What is important is that on contact surfaces the materials adhering to one another are subjected to different deformation types that are controlled by mechanical properties and geometry of these surfaces. In the paper, additional conditions that should be fulfilled for the foundation-pile-soil system to make load transfer from foundation to soil possible and safe are presented. The results of research done by the author on foundation-pile contact surface are discussed. The tests were targeted at verifying the bearing capacity of anchorage and deformation of piles made of grout and other materials from which foundations are built. The specimens were tested in tension and compression. The experiments were conducted on the amount specimens which is regarded as small sample to enable the statistical analysis of the results.

  19. Safety evaluation system for anchored vessels in Tianjin anchorage under strong wind%天津港锚地大风条件下锚泊船安全评估系统

    Institute of Scientific and Technical Information of China (English)

    吴金龙; 吴彬贵; 刘大刚; 张斌; 罗红红

    2013-01-01

    To guarantee the safety of anchored vessels under strong wind, the safe lengths of let-going chain and the safe distance between vessels are calculated, and the warning grades of anchored vessels under strong wind in Tianjin anchorage is made according to the actual condition of Tianjin anchorage. A useful safety evaluation model for anchored vessels under strong wind in Tianjin anchorage is built. On that basis, the software of safety evaluation system for anchored vessels under strong wind in Tianjin anchorage is developed, which can provide the warning grades under the coming strong wind for each anchorage area in Tianjin anchorage dynamically and visually in advance of hours according to the wind speed forecast from meteorological department. It will be helpful to confirm the safety condition of anchored vessels for marine administration before strong wind coming, and reduce the accidents of dragging and collision, which can guarantee the safety production and enhance economic efficiency for shipping companies.%为保障大风期间船舶的锚泊安全,根据天津港锚地的具体情况,计算大风条件下天津港各锚地的安全出链长度和船舶之间的安全距离,制定天津港锚地大风条件下的锚泊船预警标准,建立可用于上述条件下的锚泊船实用安全评估模型.在此基础上,研制天津港锚地大风条件下的锚泊船安全评估系统软件.该软件可根据气象部门提供的大风风速预报,提前若干小时动态直观地给出天津港各锚地在未来大风条件下的预警等级,使得海事管理部门在大风来临前能够对锚泊船的锚泊状态进行安全确认,以减少大风来临时走锚和碰撞事故的发生,达到保障船运企业安全生产、提高经济效率的目的.

  20. Movimentação de molares inferiores ancorados em mini-parafusos Mandibular molar uprighting, using mini-screw as anchorage

    Directory of Open Access Journals (Sweden)

    Rosana Canteras Di Matteo

    2005-08-01

    Full Text Available Freqüentemente a movimentação ortodôntica exige recursos adicionais de ancoragem. Os mini-parafusos têm-se apresentado como uma possível solução. O propósito deste trabalho foi estabelecer um método para a verticalização de molares inferiores inclinados para mesial, utilizando ancoragem em mini-parafusos colocados na região de linha oblíqüa externa da mandíbula. Foram selecionados três pacientes entre 40 a 48 anos (dois do gênero feminino, um do gênero masculino, com molares inferiores inclinados para mesial e distalmente posicionados às áreas edêntulas. Os pacientes foram tratados ortodonticamente durante um período de 6 a 12 meses, com técnica ortodôntica MD3. Mini-parafusos de titânio foram colocados bilateralmente com anestesia local. Uma incisão sobre a linha oblíqüa externa da mandíbula, medindo aproximadamente 1 cm foi realizada em cada lado, distalmente aos molares inclinados. Após descolamento muco-periosteal, mini-parafusos foram implantados e foram realizadas suturas deixando suas cabeças exteriorizadas. Uma semana após a remoção das suturas, cargas ortodônticas (entre 150 a 200 gramas/força foram aplicadas através de forças elásticas. Verificamos que alguma inflamação foi observada ao redor dos mini-parafusos, mas foi controlada com procedimentos de higienização. O procedimento cirúrgico é simples, podendo ser realizado pelo ortodontista; as formas dimensionais dos mini-parafusos são adequadas e estes são de fácil remoção após uso. Concluímos que o uso de mini-parafusos representa uma alternativa efetiva de ancoragem ortodôntica na verticalização de molares inferiores.Tooth movement frequently requires additional anchorage resources. Mini-screws have been used as a possible solution to this matter. The purpose of this study was to establish a method of mandibular molar uprighting, using mini-screw as anchorage, positioned on the mandibular external oblique line, behind and

  1. 基于Mindlin解的压力型锚杆锚固段的受力分析%Mechanical analysis of anchorage segment of pressure-type cable based on the Mindlin solution

    Institute of Scientific and Technical Information of China (English)

    贺建清; 胡成兵; 张建超

    2012-01-01

    假设锚杆为与周围介质相同的材料,视锚杆作用的岩土体为弹性半空间位移体;基于Mindlin位移解,求出集中力作用下周围岩土体沿锚固体的轴向位移;根据压力型锚杆锚固段的受力状态,计算锚固体在轴向荷载作用下压缩变形,利用锚固体与周围岩土体变形协调假定,推导出锚固段轴向应力和剪应力分布的理论解.经过与已有现场试验实测数据对比分析,验证了理论解的可行性,并在此基础上讨论了相关岩土参数对锚固段轴向应力和剪应力的影响.锚杆现场试验和理论分析结果表明:压力型锚杆的锚固段所受轴向应力和剪应力与锚固力成正比;压力型锚杆的锚固段所受剪应力的分布形式受周围岩土体弹模、泊松比以及锚固体与周围岩土体界面的内摩擦角等因素的影响.其中周围岩土体的弹模影响最大.%Assuming that cable has the same material properties with the surrounding rock soil and there is a displacement in an elastic half-space occurred for the rock and soil mass reinforced with cable, axial displacement of surrounding rock soil mass along cable under anchorage force was calculated based on Mindlin displacement solution. Based on the stress state of anchorage segment of pressure-type cable, the compression deformation of anchorage body under axial load was also obtained. Theoretical solutions for the distribution of axial stress and shear stress on anchorage segment of pressure-type cable were derived on the assumption of a compatible deformation between anchorage body and surrounding rock soil mass. After comparing with the existed data of in-situ test, theoretical solutions proved to be feasible. On this basis, the influence of related mechanical parameters of rock and soil on shear stress and axial stress were discussed. Experimental and theoretical analysis results indicated that the axial normal stress and shear stress on anchorage segment of

  2. Mesialização de molares com ancoragem em mini-implantes Mesial movement of molars with mini-implants anchorage

    Directory of Open Access Journals (Sweden)

    Marcos Janson

    2008-10-01

    Full Text Available INTRODUÇÃO: é muito comum, na rotina do consultório odontológico, especialmente em Ortodontia, o paciente, após avaliar o plano de tratamento proposto, questionar sobre a possibilidade de fechamento de espaços presentes, ocasionados pela perda de dentes permanentes. O ortodontista, frente a essa questão, tem que avaliar diversos fatores, tais como a má oclusão presente, a integridade do osso e das raízes, o tempo de tratamento e a geometria do posicionamento dentário, que é o que permite avaliar se, com o fechamento dos espaços e, conseqüentemente, a perda de ancoragem dos segmentos anteriores, a finalização estará de acordo com os ideais que regem a especialidade. Com o advento dos mini-implantes, as possibilidades desta abordagem terapêutica aumentaram, pois o efeito adverso da perda de ancoragem pode ser eliminado e, com isso, o paciente pode ser beneficiado. No entanto, os outros fatores envolvidos, assim como a mecânica do movimento, requerem especial atenção. OBJETIVOS: no presente artigo serão abordados os fatores envolvidos neste tipo de tratamento, o raciocínio na tomada de decisões e os detalhes importantes que devem ser observados durante a condução da mecânica, ilustrados com casos clínicos.INTRODUCTION: It's routine, especially at the orthodontic office, the patient, after the assessment of the proposed treatment plan, answer about the possibility of closing their edentulous spaces caused by missed permanent teeth. In these situations, several factors must be evaluated, like the present malocclusion, the bone and roots integrity, the treatment time and the geometry of teeth positioning, that is what permits to assess if the loss of anchorage from the anterior segments, during the space closure, would permit the occlusion to end within the orthodontic ideals. With the mini-implants, the possibilities of this therapeutic approach have been improved, since the adverse effects are eliminated with the

  3. 国内大跨径悬索桥锚碇锚固系统比较研究%The Compare and Investigation of Anchor System for Anchorage of Domestic Long-Span Suspension Bridge

    Institute of Scientific and Technical Information of China (English)

    李海; 鲜亮; 姚志安

    2011-01-01

    The anchor system for anchorage of suspension bridge plays an important controlling role in overall safety of structure . The paper mainly compares the different anchor system for anchorage of domestic long-span suspension bridge, and Makes an investigation on durability 、reliability and economy, which can be used for reference on adoption for future anchor system for anchorage of long-span suspension bridge.%悬索桥锚碇锚固系统在保证结构整体安全上具有重要控制作用.主要对我国目前大跨径悬索桥锚固系统不同体系作了比较,并对各种体系的耐久性、可靠性及经济性等方面进行了研究,为今后大跨径悬索桥锚固系统体系的采用提供了借鉴.

  4. 微种植体支抗在安氏Ⅱ类1分类错牙合中的应用%The Application of Micro-implants Anchorage in Angle Class Ⅱ Division 1 Malocclusion

    Institute of Scientific and Technical Information of China (English)

    王铭蔚

    2012-01-01

    Angle class Ⅱ division 1 malocclusion prevalence is high. The premise of such disease to be successfully treated is the perfect anchorage control. Mini-implants anchorage provides stable anchorage effects for the orthodontic treatment, which is recognized and accepted by the majority of physicians. In practical application process, how to optimize the use of micro-implants to treatment of Angle class Ⅱ division 1 malocclusion is one of the difficulties in orthodontic.%安氏Ⅱ类1分类错牙合畸形患病率较高,正确的支抗设计和良好的支抗控制是这类错牙合获得成功矫治的前提.近年来,微种植体支抗由于为正畸治疗中提供稳定支抗效果而逐渐被广大医师认识和接受.在实际应用过程中,如何优化使用微种植体治疗安氏Ⅱ类1分类错牙合是当今正畸治疗的难点之一.

  5. 提高车辆安全带锚固点强度的方法研究%Study on improving the strength of the seat-belts anchorages

    Institute of Scientific and Technical Information of China (English)

    韩淑洁

    2012-01-01

    按照国家标准要求,对某型汽车座椅安全带进行强度试验,发现后排座椅安全带锚点处的后地板破裂.针对该问题,在ANSYS软件中建立了座椅安全带的有限元模型,通过有限元分析结果与试验结果的对比,证明有限元模型的可靠性.利用非线性有限元法对安全带锚固点的强度进行了研究,提出了一些可以提高安全带锚固点强度的方法.%According to the national standards requiements , the strength test was done to the seat-belts of a certain type of cars. The results show that the strength of rear seat-belt anchorages cound not meet the national standards. According to the national standards, a finite element model of the seat-belts was built using ANSYS software. The results of the finite element simulation analysis were compared with the experimental results, which proved the reliability of finite element model. The strength of belts anchorages was studied using nonlinear finite element method, and some methods were put forward in order to improve the strength of seat-belt anchorages.

  6. The effect of canine disimpaction performed with temporary anchorage devices (TADs before comprehensive orthodontic treatment to avoid root resorption of adjacent teeth

    Directory of Open Access Journals (Sweden)

    Farzin Heravi

    2016-04-01

    Full Text Available ABSTRACT Objective: The aim of this study was to evaluate the movement of impacted canines away from the roots of neighboring teeth before full-mouth bracket placement, performed by means of TADs to decrease undesired side effects on adjacent teeth. Methods: The study sample consisted of 34 palatally impacted canines, being 19 in the experimental group and 15 in the control group. In the experimental group, before placement of brackets, the impacted canine was erupted by means of miniscrews. In the control group, after initiation of comprehensive orthodontics, canine disimpaction was performed by means of a cantilever spring soldered to a palatal bar. At the end of treatment, volume of lateral incisors and canine root resorption were measured and compared by means of a CBCT-derived tridimensional model. Visual Analogue Scale (VAS score, bleeding on probing (BOP and gingival index (GI were recorded. Clinical success rate was also calculated. Results: The volume of root resorption of lateral teeth in the control group was significantly greater than in the experimental group (p < 0.001. At the end of treatment, VAS score, GI and BOP were not significantly different between the two groups. Conclusion: Based on our results, it seems that disimpaction of canines and moving them to the arch can be done successfully carried out with minimal side effects by means of skeletal anchorage.

  7. Induction of anchorage-independent growth in primary human cells exposed to protons or HZE ions separately or in dual exposures.

    Science.gov (United States)

    Sutherland, B M; Cuomo, N C; Bennett, P V

    2005-10-01

    Travelers on space missions will be exposed to a complex radiation environment that includes protons and heavy charged particles. Since protons are present at much higher levels than are heavy ions, the most likely scenario for cellular radiation exposure will be proton exposure followed by a hit by a heavy ion. Although the effects of individual ion species on human cells are being investigated extensively, little is known about the effects of exposure to both radiation types. One useful measure of mammalian cell damage is induction of the ability to grow in a semi-solid agar medium highly inhibitory to the growth of normal human cells, termed neoplastic transformation. Using primary human cells, we evaluated induction of soft-agar growth and survival of cells exposed to protons only or to heavy charged particles (600 MeV/nucleon silicon) only as well as of cells exposed to protons followed after a 4-day interval by silicon ions. Both ions alone efficiently transformed the human cells to anchorage-independent growth. Initial experiments indicate that the dose responses for neoplastic transformation of cells exposed to protons and then after 4 days to silicon ions appear similar to that of cells exposed to silicon ions alone.

  8. Apical root resorption in maxillary incisors when employing micro-implant and J-hook headgear anchorage: a 4-month radiographic study.

    Science.gov (United States)

    Wang, Qingzhu; Chen, Wenjing; Smales, Roger J; Peng, Hui; Hu, Xiaokun; Yin, Lu

    2012-10-01

    This study evaluated, over a 4-month study period, the amount of apical root resorption occurring in maxillary central incisors following their retraction when employing either micro-implant or J-hook headgear anchorage. The prospective randomised clinical trial was conducted in Orthodontic Clinic, College of Stomatology, China from 2008-2009. Subjects are patients requiring fixed appliances on waiting list (n=20). In female Han Chinese patients aged from 16-26 years, standardized periapical radiographs from 10 randomly assigned patients with maxillary protrusions comprising the micro-implant group, and from 10 similar patients comprising the J-hook headgear group, were assessed for maxillary central incisor apical root resorption. Measurements before and after orthodontic therapy were also obtained from lateral cephalometric radiographs to calculate incisor horizontal retraction and vertical intrusion distances. Estimated retraction force vectors were calculated in horizontal and vertical directions for both treatment groups. Data analysis employed t-tests and the Pearson correlation test, with α=0.05 for statistical significance. The results showed that when compared with the J-hook group, significantly more apical root resorption shortening of the maxillary central incisors was observed in the micro-implant group (1.27 mm difference, 95% CI=0.70-1.84, Presorption shortening and maxillary central incisor retraction than when intermittent J-hook retraction was employed. The employment of continuous duration orthodontic forces presents a risk for increased apical root resorption that requires careful radiographic monitoring.

  9. Approximation and contact of the maxillary central incisor roots with the incisive canal after maximum retraction with temporary anchorage devices: Report of 2 patients.

    Science.gov (United States)

    Chung, Chooryung J; Choi, Yoon Jeong; Kim, Kyung-Ho

    2015-09-01

    The incisive canal is located on the median plane of the maxilla, posterior to the roots of the central incisor. Although the incisive canal is not considered an anatomic structure that may limit tooth movement, it has recently gained attention regarding the possibilities of surgical invasion and associated complications because of its proximity to the maxillary central incisors. In the 2 illustrated cases, lip protrusion was improved by en-masse bodily retraction of the anterior teeth (>8 mm) using temporary anchorage devices. Three-dimensional cone-beam computed tomography showed that the maxillary incisor roots were approximated to the incisive canal after maximum retraction. One central incisor root was in direct contact with the incisive canal with severe root resorption, but tooth vitality and the overall occlusion were stable in the long term without any sensory dysfunction. The apparent root resorption may be mainly related to the large amounts of anterior retraction and root movement in the 2 patients. However, the anatomic location of the incisive canal and the possibilities of its invasion after tooth movement should be closely monitored when maximum retraction is planned, to prevent potential complications.

  10. The effect of canine disimpaction performed with temporary anchorage devices (TADs) before comprehensive orthodontic treatment to avoid root resorption of adjacent teeth

    Science.gov (United States)

    Heravi, Farzin; Shafaee, Hooman; Forouzanfar, Ali; Zarch, Seyed Hossein Hoseini; Merati, Mohsen

    2016-01-01

    ABSTRACT Objective: The aim of this study was to evaluate the movement of impacted canines away from the roots of neighboring teeth before full-mouth bracket placement, performed by means of TADs to decrease undesired side effects on adjacent teeth. Methods: The study sample consisted of 34 palatally impacted canines, being 19 in the experimental group and 15 in the control group. In the experimental group, before placement of brackets, the impacted canine was erupted by means of miniscrews. In the control group, after initiation of comprehensive orthodontics, canine disimpaction was performed by means of a cantilever spring soldered to a palatal bar. At the end of treatment, volume of lateral incisors and canine root resorption were measured and compared by means of a CBCT-derived tridimensional model. Visual Analogue Scale (VAS) score, bleeding on probing (BOP) and gingival index (GI) were recorded. Clinical success rate was also calculated. Results: The volume of root resorption of lateral teeth in the control group was significantly greater than in the experimental group (p < 0.001). At the end of treatment, VAS score, GI and BOP were not significantly different between the two groups. Conclusion: Based on our results, it seems that disimpaction of canines and moving them to the arch can be done successfully carried out with minimal side effects by means of skeletal anchorage. PMID:27275617

  11. Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.

    Science.gov (United States)

    Foran, Eilis; Garrity-Park, Megan M; Mureau, Coralie; Newell, John; Smyrk, Thomas C; Limburg, Paul J; Egan, Laurence J

    2010-04-01

    Inflammatory bowel disease is characterized by chronic inflammation which predisposes to colorectal cancer. The mechanisms by which inflammation promotes tumorigenesis are not fully known. We aimed to investigate the links between colonic inflammation and tumorigenesis via epigenetic gene silencing. Colon cancer specimens were assessed for the expression of DNA methyltransferase-1 (DNMT-1) using immunohistochemistry. Colorectal carcinoma cell lines were assessed for DNMT1 expression, methylcytosine content, promoter methylation, gene expression, and tumorigenesis in response to interleukin (IL)-6. DNMT1 was expressed at higher levels in both the peritumoral stroma and tumor in inflammatory bowel disease-associated cancers compared with sporadic colon cancers. IL-6 treatment of colon cancer cells resulted in an increase in DNMT1 expression, independent of de novo gene expression. IL-6 increased the methylation of promoter regions of genes associated with tumor suppression, adhesion, and apoptosis resistance. Expression of a subset of these genes was downregulated by IL-6, an effect that was prevented by preincubation with 5-azadeoxycytidine, a DNMT1 inhibitor. Anchorage-independent growth and migration of colon cancer cells was also increased by IL-6 in a 5-azadeoxycytidine-sensitive manner. Our results indicate that DNMT-mediated gene silencing may play a role in inflammation-associated colon tumorigenesis.

  12. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

    Institute of Scientific and Technical Information of China (English)

    Julia Schultz; Peter Lorenz; Gerd Gross; Saleh Ibrahim; Manfred Kunz

    2008-01-01

    A microRNA expression screen was performed analyzing 157 different microRNAs in laser-microdissected tissues from benign melanocytic nevi (n=10) and primary malignant melanomas (n=10),using quantitative real-time PCR.Differential expression was found for 72 microRNAs.Members of the let-7 family of microRNAs were significantly downregulated in primary melanomas as compared with benign nevi,suggestive for a possible role of these molecules as tumor suppressors in malignant melanoma.Interestingly,similar findings had been described for lung and colon cancer.Overexpression of let-7b in melanoma cells in vitro downregulated the expression of cyclins D1,D3,and A,and cyclin-dependent kinase (Cdk) 4,all of which had been described to play a role in melanoma development.The effect oflet-7b on protein expression was due to targeting of 3'-untranslated regions (3'UTRs) of individual mRNAs,as exemplified by reporter gene analyses for cyclin DI.In line with its downmodulating effects on cell cycle regulators,let-7b inhibited cell cycle progression and anchorage-independent growth of melanoma cells.Taken together,these findings not only point to new regulatory mechanisms of early melanoma development,but also may open avenues for future targeted therapies of this tumor.

  13. CFRP筋锚固体系研究与应用现状%Research and Application Situation of CFRP Tendon Anchorage System

    Institute of Scientific and Technical Information of China (English)

    刘荣桂; 李明君; 蔡东升; 刘德鑫

    2012-01-01

    为促进碳纤维增强复合材料(CFRP)这一具有密度小、抗拉强度高、抗疲劳、耐腐蚀等特性材料的研究工作与在土木工程结构中的实际应用,主要介绍了各国有关CFRP筋及其锚具研究和应用的最新进展,分别对粘结型、夹片型、复合型3类现有的主要类型锚具的锚固机理、代表性试验研究和数值分析等方面做了整理和归纳,并提出了锚具开发和应用的一些关键问题和建议.%In order to promote the future research and application of carbon fiber reinforced polymer (CFRP) for civil engineering structures, with the characteristics of low specific gravity, high tensile strength, high fatigue resistance and corrosion resistance, an introduction was given on the latest research and application progress of CFRP tendon and anchors for all countries. The anchorage mechanism, typical experiment investigations and numerical analysis of exist main types of anchors, including bond-type anchor, wedge-type anchor and wedge-bond anchor, were also classified and summarized. Finally, some critical problems and advices in anchor development and utilization were provided.

  14. Doxycycline-Regulated p16(MTS1) Expression Suppresses the Anchorage-Independence and Tumorigenicity of Breast Cancer Cell Lines that Lack Endogenous p16.

    Science.gov (United States)

    Todd, Maria C; Langan, Thomas A; Sclafani, Robert A

    2017-01-01

    The RB pathway controls the critical transition from G1 into S phase of the mammalian cell cycle. Deregulation of the RB pathway by means of RB or p16 inactivation has been implicated in the development of virtually all human cancers. Such findings have led to the view that the loss of RB-mediated regulation at the G1/S checkpoint is a precondition for human malignancy. Our analysis of the RB-positive MCF-7 and ZR75.1 breast cancer cell lines revealed a lack of endogenous p16 protein expression as a result of the homozygous deletion and methylation of the p16 gene at the CDKN2A locus, respectively. We employed the TET-OFF inducible expression system to investigate the effects of non-growth inhibitory levels of functional p16 protein upon the in vitro and in vivo transformed properties of the MCF-7 and ZR75.1 cell lines. Stable transfectants of MCF-7 and ZR75.1 cells were isolated that expressed different levels of p16 protein in the absence of doxycycline (DOX) but continued to proliferate in culture. Transfectants that expressed modest levels of p16 (relative to SV40 T antigen-transformed HBL-100 breast epithelial cells) demonstrated a marked suppression of anchorage-independent growth in soft agar. Further, the induction of moderate and high levels of p16 (relative to HBL-100) resulted in the suppression of tumorigenicity of both MCF-7 and ZR75.1 cells as assayed by injection into nude mice. From these data, we concluded that RB pathway restoration by non-growth inhibitory levels of p16 protein was sufficient to revert breast cancer cells to a non-transformed and non-tumorigenic state.

  15. Doxycycline-Regulated p16MTS1 Expression Suppresses the Anchorage-Independence and Tumorigenicity of Breast Cancer Cell Lines that Lack Endogenous p16

    Science.gov (United States)

    Todd, Maria C; Langan, Thomas A; Sclafani, Robert A

    2017-01-01

    The RB pathway controls the critical transition from G1 into S phase of the mammalian cell cycle. Deregulation of the RB pathway by means of RB or p16 inactivation has been implicated in the development of virtually all human cancers. Such findings have led to the view that the loss of RB-mediated regulation at the G1/S checkpoint is a precondition for human malignancy. Our analysis of the RB-positive MCF-7 and ZR75.1 breast cancer cell lines revealed a lack of endogenous p16 protein expression as a result of the homozygous deletion and methylation of the p16 gene at the CDKN2A locus, respectively. We employed the TET-OFF inducible expression system to investigate the effects of non-growth inhibitory levels of functional p16 protein upon the in vitro and in vivo transformed properties of the MCF-7 and ZR75.1 cell lines. Stable transfectants of MCF-7 and ZR75.1 cells were isolated that expressed different levels of p16 protein in the absence of doxycycline (DOX) but continued to proliferate in culture. Transfectants that expressed modest levels of p16 (relative to SV40 T antigen-transformed HBL-100 breast epithelial cells) demonstrated a marked suppression of anchorage-independent growth in soft agar. Further, the induction of moderate and high levels of p16 (relative to HBL-100) resulted in the suppression of tumorigenicity of both MCF-7 and ZR75.1 cells as assayed by injection into nude mice. From these data, we concluded that RB pathway restoration by non-growth inhibitory levels of p16 protein was sufficient to revert breast cancer cells to a non-transformed and non-tumorigenic state.

  16. Reinforcing of deposit slopes of Xiaowan Hydropower Station and application of prestressed anchorage cables%小湾水电站堆积体边坡支护与锚索技术应用

    Institute of Scientific and Technical Information of China (English)

    张德圣; 姜玉松; 吴诗勇

    2011-01-01

    With regard to the deposit slopes of Xiaowan Hydropower Station, the relevant reinforcing measures were analyzed, and the application of prestressed anchorage cables was highlighted. The results indicate that the slope reinforcements in the study area comprehensively adopt engineering protection and ecological protection techniques. The pre-stressing anchorage cables are the principal part of the engineering, and their drilling and grouting are the difficulty and keystone of the anchorage technology. The technology of concentric drilling and eccentric drilling with pipes can availably solve boring problem. By wrapping geotextile and thin canvas outside the prestressed steel strand, it can make concrete calculi protect steel strand of tensile section and reduce grouting quantity so as to avoid grouting waste.%分析小湾水电站堆积体边坡支护措施,研究预应力锚索技术的应用.分析认为,研究区边坡支护综合运用了工程护坡和生态护坡等边坡处理技术,预应力锚索是其主体工程,锚索孔钻孔和灌浆是该技术应用中的难点和重点,使用偏心跟管钻进技术和同心跟管钻进技术能有效解决钻孔难以成孔的问题;通过在锚索体外裹土工布和细帆布的方法,既保证了水泥结石对自由段锚索体的保护,又减少了浆量损耗,避免浆体浪费.

  17. 钢锚梁式钢-混组合索塔锚固体系设计与分析%Design and Analysis of Steel-concrete Composite Anchorage Structure with Steel Anchor Beam

    Institute of Scientific and Technical Information of China (English)

    苗通; 孙蕊鑫

    2015-01-01

    A bridge is a twin towers and double cable plane prestressed concrete girder cable -stayed bridge with a span arrangement of (130 +300 +130)m,and the tower type is inverted Y and the Steel -concrete Composite anchorage structure with Steel Anchor Beam is used to anchorage the cable of end of the tower.Among this type anchorage system,the anchor boxes have been welded on both sides of the steel anchor beam,at the same time, using steel bracket to replace traditional concrete corbel structure.In this paper,the characteristics of this kind of anchor system has been introduced and the stress situation of this kind of anchor system has been analyzed u-sing the finite element method.The research conclusion can provide a reference for the design of this type of ca-ble pylon anchorage system.%某斜拉桥主桥是一座跨径布置为(130m +300m +130m)的双塔双索面预应力混凝土梁斜拉桥,索塔采用倒 Y 型,斜拉索在桥塔端采用新型空间索面钢锚梁式钢-混组合索塔锚固体系进行锚固。该型锚固体系将锚箱焊在钢锚梁两侧,同时采用钢牛腿替换传统的混凝土牛腿结构,提高了施工速度,改善了结构受力。介绍了该种锚固体系的特点,并采用有限元方法对改型索塔锚固体系的受力情况进行了分析,可为该类型索塔锚固体系设计提供参考。

  18. Design of cable-girder anchorage system scheme in self-anchored suspension bridge%自锚式悬索桥缆-梁锚固系统方案设计

    Institute of Scientific and Technical Information of China (English)

    凌云

    2015-01-01

    本文根据已建以及待建自锚式悬索桥工程实例,将自锚式悬索桥工程中主缆在加劲梁梁端的锚固方案进行了总结分析,从施工方面、经济性以及美观性等方面指出了各种锚固方式的优缺点以及适应性。按照锚体材料的不同将现有锚固方式重新进行了分类,综合现有的分类方式提出了一套锚固系统方案设计流程。这种设计流程条理清楚、直观易理解,为今后的自锚式悬索桥主缆锚固系统设计提供指导,快速的形成锚固系统方案,提高设计效率,并获得更好的经济性和美观性。%According to the engineering examples of the self -anchored suspension bridges built and to be built , the cable -girder an-chored projects are summarized and analyzed.From the construction , economy and aesthetics aspects , the advantages adaptability of vari-ous ways of anchoring and are pointed out.According to the different materials of the existing anchorage , the way of anchoring is re -clas-sified and a set of anchor system design process is put forward based on the classification of the existing anchorage systems .This design process is clear , intuitive and easy to understand and can provide guidance for the design of self -anchored suspension bridge main cable anchorage system in the future.Using this design process , anchorage system scheme will be quickly put forward , the design efficiency can be improved and the bridge will be more economic and more beautiful.

  19. 预应力纤维布混合锚固分析与试验研究%Analysis and Testing Study of Hybrid Anchorage of Prestressed FRP

    Institute of Scientific and Technical Information of China (English)

    李青松; 孟少平; 单岗; 王侠伟

    2011-01-01

    In order to improve the deficiency in the technology of embedded prestressed FRP reinforcement, with the principle of anchoring bond and additional mechanical anchoring working together, the tensioning end of prestressed FRP is anchored twice after the tension and bonding of the FRP, then removing the existing fixture and anchor. To ensure the reliability of anchoring, the paper makes a theoretical analysis of the performance of the bonding layer in the anchoring end and an experimental research on hybrid anchoring end. The research results show that the change of the performance in the bonding layer improves its anchoring ability significantly, and the steel plate can be squeezed to provide pressure to improve and enhance the performance of the bonding layer,which guarantee the quality of anchoring end. The method of combining bonding layer with hybrid anchorage of the steel plate can provide the adequate anchoring capacity, improve the construction techniques, lessen the cost and the boost the application of prestress FRP reinforcement in the practical constructions.%为了改善嵌人式预应力纤维布(FRP)加固技术的不足之处,利用粘结与机械锚固共同工作的原理,在预应力FRP张拉粘贴完毕后,对张拉端进行二次锚固,粘结层硬化后拆除原有锚夹具.为保证锚固端的可靠性,本文对锚固端粘结层的性能进行了理论分析,并对混合锚固端进行了试验研究.研究结果表明:通过改变粘结层的性能,可大幅度提高粘结层的锚固能力;钢板压条可提供挤压力,改善和提高了粘结层的受力性能,便于保证锚同端施工质量,可靠性好.采用粘结层与钢板压条混合锚固的方式可为预应力FRP提供足够的锚固力,改善了施工工艺,明显降低加固成本,促进了预应力FRP加固技术在实际工程中的应用.

  20. Abduction of Toe-excavation Induced Failure Process from LEM and FDM for a Dip Slope with Rock Anchorage in Taiwan

    Science.gov (United States)

    Huang, W.-S.; Lin, M.-L.; Liu, H.-C.; Lin, H.-H.

    2012-04-01

    On April 25, 2010, without rainfall and earthquake triggering a massive landslide (200000 m3) covered a 200m stretch of Taiwan's National Freeway No. 3, killing 4 people, burying three cars and destroying a bridge. The failure mode appears to be a dip-slope type failure occurred on a rock anchorage cut slope. The strike of Tertiary sedimentary strata is northeast-southwest and dip 15˚ toward southeast. Based on the investigations of Taiwan Geotechnical Society, there are three possible factors contributing to the failure mechanism as follow:(1) By toe-excavation during construction in 1998, the daylight of the sliding layer had induced the strength reduction in the sliding layer. It also caused the loadings of anchors increased rapidly and approached to their ultimate capacity; (2) Although the excavated area had stabilized soon with rock anchors and backfills, the weathering and groundwater infiltration caused the strength reduction of overlying rock mass; (3) The possible corrosion and age of the ground anchors deteriorate the loading capacity of rock anchors. Considering the strength of sliding layer had reduced from peak to residual strength which was caused by the disturbance of excavation, the limit equilibrium method (LEM) analysis was utilized in the back analysis at first. The results showed the stability condition of slope approached the critical state (F.S.≈1). The efficiency reduction of rock anchors and strength reduction of overlying stratum (sandstone) had been considered in following analysis. The results showed the unstable condition (F.S. <1). This research also utilized the result of laboratory test, geological strength index(GSI) and finite difference method (FDM, FLAC 5.0) to discuss the failure process with the interaction of disturbance of toe-excavation, weathering of rock mass, groundwater infiltration and efficiency reduction of rock anchors on the stability of slope. The analysis indicated that the incremental load of anchors have

  1. Caracterização de mini-implantes utilizados na ancoragem ortodôntica Characterization of the mini-implants used to orthodontic anchorage

    Directory of Open Access Journals (Sweden)

    Luciana Rougemont Squeff

    2008-10-01

    Full Text Available INTRODUÇÃO: o diâmetro reduzido do mini-implante, e a decorrente facilidade na sua inserção, minimizam a possibilidade de erro do operador e de contato entre a rosca do mini-implante e a raiz dentária. Entretanto, o risco de fratura da peça aumenta à medida que seu diâmetro é diminuído. MÉTODOS: neste trabalho foram analisados quatro produtos de marcas nacionais (INP, SIN, Conexão e Neodente e um de marca alemã (Mondeal, com o objetivo de identificar características importantes para o bom desempenho deste recurso como acessório de ancoragem. Foram observados composição e design das peças e realizado o ensaio mecânico de torque até a fratura (estudo in vitro, cujos valores foram submetidos à análise de variância (ANOVA e teste de Tukey. RESULTADOS: os resultados mostraram que todos os mini-implantes testados estão aptos à utilização clínica como reforço de ancoragem ortodôntica.INTRODUCTION: The reduced diameter of the mini-implants and the simplicity of the technique could minimize the operator mistake's possibility and avoid the contact between the thread of the screw and the dental root. In spite of that, it increases the fracture risk because of the diameter's decrease. METHODS: At the present work, mini-implants from five different trade marks, four Brazilian systems (INP, SIN, Conexão and Neodente and a German system (Mondeal were studied to identify important characteristics of this anchorage accessory, like composition, design and resistance to the insertion torque (in vitro. The values obtained from the mechanical torque test were submitted to variance analysis (ANOVA and Tukey's test. RESULTS: All studied groups presented good results and are recommended to orthodontic clinic use.

  2. Analysis of clinical results of micro - screw implant anchorage in treatment of orthodontics%微螺钉种植体支抗在口腔正畸中的临床效果分析

    Institute of Scientific and Technical Information of China (English)

    宋勇

    2011-01-01

    Objective To investigate the clinical effects of micro - screw implant anchorage in treatment of orthodontics. Methods Diagnostic criteria for selecting hospital 50 cases of the wrong jaw deformity patients, randomized into study group and control group, each 25 patients. Study group received treatment micro - screw implant anchorage and the control group with non - implant anchorage is strong anchorage extraoral bow treatment, the whole story are two groups were taken in the treatment of lateral head positioning, analyzed the X - ray cephalometry and compared group methods in orthodontic anchorage in the clinical effect. Results By comparison, the study group total effective rate was 96% , efficacy was significantly better than the control group, 64% , (P < 0. 05) ; Study group the incidence of complications such as root resorption was 30% higher than the 21% (P < 0. 05), study group underwent micro - screw implant anchorage treatment, and convex on the angle from the central incisor as Ul/SN(on the central incisor - SN angle) , L1/MP(lower central incisor - MP plane angle) , U1 - L1 (on - under the central incisor angle) , NLA( nasolabial angle) , UIE - OTV (the upper incisors to the PTV margin vertical distance) , LIA - PTV ( PTV lower incisor tip to the vertical distance) , U6 - PTV ( maxillary first molar buccal tip vertical distance between PTV) and X - ray cephalometry reduction targets significantly more than the control group, the difference was statistically significant ( P < 0. 05). Conclusions Micro - screw implant anchorage in orthodontics in a significant effect, but either have a certain rate of occurrence of root resorption, its effect was significantly better than non - orthodontic implant anchorage, worthy of clinical use.%目的 探讨微螺钉种植体支抗在口腔正畸中的临床效果.方法 按诊断标准选取宿迁市人民医院50例错颌畸形患者,按就诊顺序随机分为研究组和对照组,各25例.其中研究组给予微

  3. Do-ocracy's democratic anchorage

    NARCIS (Netherlands)

    Verhoeven, I.; Metze, T.; van de Wijdeven, T.

    2014-01-01

    Amidst the worldwide euphoria among public authorities and political scientists for direct forms of democracy such as participatory budgeting, we see an increasing (policy) attention for another form of direct democracy, which can be labeled ‘do-ocracy’. Do-ocracy refers to active citizens who wish

  4. 种植体支抗辅助舌侧矫治双牙弓前突畸形的临床研究%A clinical study of protruding cases by using lingual appliance and mini screw anchorage

    Institute of Scientific and Technical Information of China (English)

    武冠英; 杨琳; 马俐丽; 徐宝华

    2013-01-01

    目的 通过头影测量比较种植体支抗辅助舌侧隐形矫治双牙弓前突患者治疗前后牙颌面结构的变化.方法 随机选取20例双牙弓前突畸形患者,均使用舌侧矫治器配合微螺钉种植体支抗矫治,观察微螺钉种植体的稳定性,并对患者治疗前后的头颅侧位片进行头影测量,评价治疗效果.结果 微螺钉种植体的成功率为97.5%.上颌第一磨牙平均近中移动0.23 mm±0.76 mm(P>0.05),上中切牙切端平均远中移动5.31 mm±2.02 mm(P<0.001),治疗后U1-SN角度为99.4度.结论 舌侧隐形正畸联合微螺钉种植体支抗治疗双牙弓前突患者,能够有效控制磨牙支抗,在内收上颌前牙的同时能有效控制转矩,达到了良好的治疗效果.%Objective To study the dentofacial changes of protruding cases after treatment by using lingual appliance and mini screw anchorage.Methods 20 randomly selected protruding cases were treated by lingual appliance and mini screw anchorage.In order to evaluate the effect of the treatment,the stability of mini screw anchorage were observed and cephalometrics were done.The traditional lingual bracket and the base of the individual lingual bracket were integrated.The manufactured individual lingual brackets were used to treat the patients.The patients included 68 Class I,27 Class Ⅱ and 9 Class Ⅲ cases.Various kinds of malocclusions were included,such as protrusion,open bite,deep bite,cross bite,crowding and impaction.Results The success rate of mini screw anchorage is 97.5 %.The upper first molars moved mesially an average of 0.23 mm.The central incisors moved distally an average of 5.31 mm.The angle of U1-Sn was 99.4°after lingual orthodontic treatment.Conclusions The anchorage of molars can be controlled effectively by lingual appliance with micro-implant.Also the torque of anterior teeth can be controlled effectively and get good results.

  5. 微种植体支抗治疗开唇露齿的相关牙根吸收的研究%Root resorption of patients used mini-implant anchorage to treat poor lip seal

    Institute of Scientific and Technical Information of China (English)

    陈馨; 王林; 沈小波; 冯兴梅

    2013-01-01

    Objective:To evaluate the outcome and factors of root resorption in patients who used mini-implant to treat poor lip seal. Methods: Eighteen subjects(age 12-23 years) with poor lip seal were allocated in the study. The patients all had maxillary dentoalveolar protrusion and extrated two first premolars. They were divided into two groups:A group (mini-implant anchorage) 9 patients and B group (regular anchorage) 9 patients. A group used 3 implants and B group used Nance plate for the treatment. The length of incisors was measured in record model , panoramic and cephalometric radiograph. Results: Root resorption was found in both group. The degree of the root resorption in mini-implant anchorage group was higher than that in reg-ular anchorage (P<0.05). Conclusions:Root resorption was found in all of the patients with poor lip seal. The use of mini-implant anchorage will lead more root resorption. The force chose and early imaging examination should be noticed during the treatment.%目的:探讨使用微种植体支抗辅助治疗开唇露齿后牙根吸收的状况及相关因素。方法:选取18例开唇露齿采取正畸治疗的患者,年龄12~23岁,上颌或双颌前突,前牙唇倾,上颌均拔除第一前磨牙。分为实验组(种植支抗)9例和对照组(传统支抗)9例,实验组使用前后牙区共3枚种植钉支抗系统,对照组使用Nance托。正畸前后制取模型及拍摄全景片,头颅定位侧位片,测量相关指标并进行分析。结果:两组患者的上中切牙牙根均明显吸收,微种植支抗组大于传统支抗组(P<0.01)。结论:治疗开唇露齿的患者,前牙内收压低后均有不同程度的牙根吸收,使用微种植体支抗会更明显,治疗期间需注意力量控制及影像监测。

  6. 碳纤维增强复合材料筋复合型锚具试验研究和有限元分析%EXPERIMENTAL INVESTIGATION AND FINITE ELEMENT ANALYSIS OF WEDGE-BOND ANCHORAGE FOR CFRP-TENDONS

    Institute of Scientific and Technical Information of China (English)

    刘荣桂; 李明君; 刘德鑫; 蔡东升; 谢桂华

    2012-01-01

    In order to colligate the virtue of bonding-anchor and wedge-anchor, the wedge-bond anchorage for CFRP tendons was investigated, which was made by bonding and wedge parts, working in parallel. Based on the characteristics of exiting CFRP tendon anchors and according to a series of static load tests, it was studied the bonding property of colloid, and the influence of bond length, colloids thickness on the performance of straight pipe bonding anchorage. The static load test of wedge-bond anchorage was conducted to investigate its failure mode, ultimate load, slip deformation, etc. Transport mechanism of anchorage stress is preliminarily analysed according to variation of actual stress in the anchorage zone. The influences of variation in specific parameters, such as wedge slope, angular differential, presetting load, on the internal stress of the anchorage were simulated by using finite element method. And the suggested design parameters were offered. Which can provide academic reference for the optimization of wedge-bond anchorage.%为综合粘结型锚具与夹片型锚具各自的优点,在已有碳纤维增强复合材料(简称CFRP)筋锚具的基础上,研究由粘结部分与夹持部分协同工作而成的复合型锚具。由直筒粘结型锚具的静载试验,研究胶体粘结性能,粘结长度、胶体厚度对锚固性能的影响。通过复合型锚具静载试验,研究该类锚具的失效模式、极限荷载、滑移变形等,结合锚固区实测应力变化,初步分析锚固应力的传递机制。通过有限元分析方法,模拟计算夹片倾角、锥角差、预紧力等参数对复合型锚具内部受力的影响,得到建议设计参数,为复合型锚具结构优化提供参考。

  7. Study of Mechanical Behavior and Ultimate Carrying Capacity of Suspender Anchorage Zone in Axial Direction of Bridge%顺置式吊杆锚固区受力特性与极限承载力研究

    Institute of Scientific and Technical Information of China (English)

    高小妮; 贺拴海; 齐宏学

    2012-01-01

    To have an understanding of the mechanical behavior and ultimate carrying capacity of suspender anchorage zone set in the axial direction of bridge under the action of suspender forces, a combined cable-stayed and self-anchored suspension system bridge that was being constructed was cited as an example, the software ANSYS was used to set up the spatial shell finite element model, the mechanical behavior of the anchorage zone under the action of the worst load was studied, the ultimate carrying capacity of the anchorage zone was analyzed, respectively u-sing the linear elasticity and nonlinearity analysis methods and the force conditions of the components in the anchorage zone were discussed. The results of the study show that under the action of the worst load, the stress in the steel anchor box and steel anchor beam is less than that in the diaphragm. With the exception that the stress concentration in the welding of the steel anchor beam and diaphragm is notable, the stress distribution in all components is uniform and the deformation of the components in the axial direction of the bridge is great. The results of the different analysis methods for the ultimate carrying capacity also show that when the ultimate carrying capacity of such type of the structure is analyzed, using the shell element model, the material nonlinearity should considered only and in the design of the structure, it is proposed that adequate attention should be paid to the problem of insufficient rigidity of the diaphragm.%为掌握顺桥向设置的吊杆锚固区在吊杆力作用下的受力特性和极限承载力,以某在建斜拉—自锚式悬索组合体系桥为依托工程,利用ANSYS软件建立壳单元空间有限元模型,对锚固区在最不利荷载作用下的受力性能进行研究;并分别采用线弹性及非线性分析方法对吊杆锚固区极限承载力进行分析,讨论构件的受力情况.结果表明:在最不利荷载作用下,钢锚箱及钢锚梁

  8. Effect of surface active compounds on growth and adhesion of anchorage-dependent animal cells at liquid/liquid interface; Eki/ekikaimen ni okeru fuchaku izonsei dobutsu saibo no zoshoku oyobi fuchaku ni taisuru kaimen kassei busshitsu no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Shiba, Y.; Oshima, T.; Sato, M. [Gunma Univ., Kiryu (Japan). Faculty of Technology

    1998-03-01

    A cell cultivation using a liquid/liquid (culture medium/fluorocarbon) interface has been practiced as a novel culturing method for anchorage-dependent animal cells, and it is known that cell adhesion at the interface is dependent on the contaminants contained in the hydrophobic liquid. Substances effective for the adhesion and growth of cells are investigated using various surfactants. As a result of comparison of ionic and nonionic surfactants, cell adhesion is observed when ionic surfactant is used, indicating the importance of the electric charge of surfactant. Cell growth is better when ionic surfactant is added to fluorocarbon than when surfactant is added to the culture medium. The cell growth using fluorocarbon added with pentafluorobenzoyl chloride and perfluorooctanoyl chloride is similar to that of culturing using polystyrene, and the importance of surfactant addition to fluorocarbon is indicated. 7 refs., 4 figs.

  9. 微种植钉支抗辅助矫治上颌阻生尖牙的临床研究%Clinical research of micro-implant anchorage in treatment for impacted maxillary canines

    Institute of Scientific and Technical Information of China (English)

    包丽娜; 任柏林; 熊红珍; 包丽杰; 温兴涛

    2015-01-01

    目的:探讨微种植钉支抗矫治上颌阻生尖牙的临床效果。方法术前拍摄锥形束CT(cone-beamCT, CBCT)明确诊断和定位患牙,以微种植钉为支抗对15例(16颗)上颌阻生尖牙进行外科-正畸联合治疗。测量矫治前后阻生尖牙、矫治后对侧健康尖牙长轴与正中矢状面的交角角度,牙尖顶端到牙合平面的距离,对结果进行比较分析。结果16颗阻生尖牙均牵引到位,牙周牙髓健康。治疗前阻生尖牙长轴与正中矢状面的交角平均为(32.06±5.07)°,治疗后为(-6.56±2.53)°;牙尖到牙合平面的距离平均为(13.59±1.05) mm,治疗后为(-0.58±0.26) mm。矫治前后阻生尖牙数值对比,差异均有统计学意义(P<0.05)。矫治后阻生尖牙与对侧健康尖牙相比,差异均无统计学意义( P>0.05)。结论在CBCT的准确定位下,使用微种植钉作为支抗牵引上颌埋伏阻生尖牙可取得良好的临床治疗效果。%Objective To investigate the clinical effect of micro-implant anchorage on the treatment of impacted max-illary canines.Methods Sixteen impacted maxillary canines from 15 patients were diagnosed and located by cone-beam CT ( CBCT) before treatment, and they were treated by micro-implant anchorage with surgical exposure and orthodontic alignment.The angle of canine axis to the median sagittal plane and the distance of canine cusp to the occlusal plane of the impacted canines were measured before and after treatment and the contralateral healthy canines after treatment, then the results were compared.Results Sixteen impacted maxillary canines were towed successfully to proper position with pulpal and periodontal health.The average angle of pre-treatment impacted canines axis to the median sagittal plane was (32.06 ±5.07)°;the average distance of cannine cusp to the occlusal plane was (13.59 ±1.05) mm;there were sig-nificant difference between

  10. A clinical cephalometric study of mini-implant anchorage for en-masse retraction of eight maxillary anterior teeth%微种植体辅助整体内收上前牙段的头影测量

    Institute of Scientific and Technical Information of China (English)

    张华; 麦志辉; 卢红飞; 艾虹; 文冲

    2011-01-01

    目的:研究微种植体支抗在矫治上颌前突病例中整体内收上前牙段的应用.方法:选择5例上颌前突患者,拔除第二前磨牙,采用直丝弓矫治技术,辅以微种植体支抗同时整体内收前牙段(6个前牙及2个第一前磨牙),通过X线头影测量分析,观察矫治前后上颌骨软硬组织的变化.结果:上颌骨的变化轻微;切牙平均内收(4.6±1.5)mm,压低(0.8±1.1)mm,根尖后移(1.7±1.4)mm,切牙与腭平面的夹角减少(6.8±3.5)度;支抗磨牙水平前移(0.5±0.3)mm,没有出现明显的颌向伸长;上唇突度减少(2.0±0.9)mm,鼻唇角增大(3±2.4)度.结论:微种植体能提供稳定的支抗,同时整体内收上前牙段,最大限度避免支抗的丧失,改善上唇突度.%Aim: To Study the efficiency of mini-implants as intraoral anchorage units for en-masse retraction of the 6 maxillary anterior teeth and 2 first premolars after the second premolars are extracted. Methods: Five patients requiring high anchorage after extraction of the maxillary second premolars were selected for this study. Straight wire appliance and mini-implants were used for en-masse retraction, Horizontal , vertical, and angular positions of the maxillary ? Rst molar and central incisor were evaluated ceph-alometrically before and after orthodontic retraction. Results; The edge of upper incisors were retracted (4. 6 ±1. 5)mm and intruded (0. 8 ±1. L)mm, the root apex moved distally (1. 7 ± 1.4)mm. The maxillary first molars showed mesial movement of (0. 5 ±0. 3)mm. The nasolabial angle increased (3 ±2.4)° and the angle between upper incisor and PP-plane decreased (6. 8 ± 3. 5 ) °. Conclusion: Mini-implants are efficient for intraoral anchorage reinforcement for en-masse retraction and intrusion of maxillary anterior teeth.

  11. 下颌支种植体支抗辅助下牙列内收的疗效评价%Clinical study of ramus implant anchorage for mandibular arch distalization

    Institute of Scientific and Technical Information of China (English)

    毛丽霞; 房兵; 沈国芳; 夏韫晖; 袁玲君

    2011-01-01

    PURPOSE: To evaluate the efficiency of ramus implant anchorage for mandibular arch distalization, and determine the feature of tooth movement. METHODS: Six patients were selected to distalize mandibular arch with ramus implant anchorage. Position changes of mandibular first molars and incisors were measured in sagittal and vertical direction to evaluate the amount of molar and incisor distalization and character of tooth movement. SPSS 17.0 software package was used for statistical analysis. RESULTS: The average amount of distalization of mandibular first molar was 4.88mm at crown level and 3.1mm at root level, and of mandibular incisor was 5.02mm at crown level and 1.03mm at root level. All of the lower arches were distalized successfully and achieving normal overjet and overbite. CONCLUSIONS: Significant true distalization of lower arch could be obtained by ramus implant as bony anchorage. The method could be used to correct anterior cross bite and mandibular anterior crowding or flaring without extraction. Supported by National Natural Science Foundation of China (10972142), Research Fund of Science and Technology Commission of Shanghai Municipality(08411961600) and Innovative Research Team of Shanghai Municipal Education Commission.%目的:应用下颌支种植支抗钉远中移动下颌牙列,评价该方法的有效性,探索牙移动的特点.方法:选择6例需要远中移动下颌牙列的患者,在双侧下领支前缘植入种植支抗钉,加力于下颌尖牙远中,拉下牙列向远中移动.测量治疗前、后下颌切牙和第一磨牙冠根水平矢状向、垂直向位置,运用SPSS 17.0软件包对治疗前、后各测量项目进行配对t检验,评价切牙和磨牙远中移动量及移动方式.结果:6例患者均获得较理想的治疗效果,达到正常覆(牙合)、覆盖和尖窝关系.下颌第一磨牙远中移动量在牙冠水平平均为4.88mm,在牙根水平平均为3.1 mm,下颌切牙切缘远中移动平均为5.02mm,

  12. 微小种植体支抗压低前牙改善露龈笑的临床研究%Clinical Application of Miniscrew Implant anchorage for Intruding upper incisors in patients with gummy smile

    Institute of Scientific and Technical Information of China (English)

    沈焕; 王蕾; 法永红; 蔡兴伟; 李亚朋; 李冬黎

    2011-01-01

    目的:评价利用微小种植体作为支抗压低前牙改善露龈笑的临床效果.方法:选取我科室9例(男5例,女4例)前牙过长,开唇露齿露龈笑的深覆(牙合)病例,年龄18.6~28.3岁,平均24.7岁.9例患者前牙区存在Ⅱ度或Ⅲ度深覆(牙合),5例病例伴有不同程度的牙列前突.9例患者在佩戴固定戴矫治器后在上、下颌前牙区相应部位植入微小种植体,治疗前后拍摄全口曲面断层片进行测量对比,观察切牙的变化和改善露龈笑的情况.结果:9例患者治疗前后上下颌前牙均有不同程度的压低,上颌前牙平均压低3.8mm,下颌切牙平均压低3.0mm,深覆(牙合)得到有效的治疗,同时露龈笑有一定程度的改善.其中2例患者出现一定程度的牙根吸收.结论:利用微小种植体支抗能有效地治疗前牙过长开唇露齿,达到真正压低前牙解除深覆(牙合)的效果.%Objective This study aims to evaluate the clinical effect of improving gummy smile by micro-implant anchorage for the anterior teeth intrusion.Methods 9 patients have been diagnosed with anterior teeth Ⅱ °or Ⅲ °deep overbite with gummy smile and incompetent lips, 5 males and 4 females, aged from 18.6 to 28.3 years, with the average of 24.7 years and 5 patients presents with protruding anterior teeth.Miniscrew Implants are inserted into the situation with fixed orthodontic appliances.Results All patients are taken panoramic radiograph before and after treatment.The edges of maxillary incisors are avergely intruded 3.8mm and mandibular incisors are avergely intruded 3.0mm.There are some degree of root resorption in 2 patients.Conclusion Miniscew implant anchorage can provide necessary anchorage to retract the front teeth in the clinical treatment of gummy smile and incompetent tips

  13. Dentofacial three-dimensional changes after maxilla retraction with zygomatic implant anchorage in rhesus monkeys%颧骨种植体支抗后牵引猴上颌骨颅颌面三维形态学研究

    Institute of Scientific and Technical Information of China (English)

    史聪翀; 张晓蓉; 黄家昕; 邓怡

    2011-01-01

    Objective: To observe dentofacial three-dimensional changes after maxillar retraction with zygomatic implant anchorage in rhesus monkeys. Methods: 4 young male rhesus monkeys were employed. Maxillar retraction was performed with zygomatic implant anchorage in 3 monkeys( 1 for 1.5 month and 2 for 3 month observation), 1 without treatment was used as the control. Spiral CT images were used to analysis the dentofacial three dimensional changes after the retraction. Results: There was obvious sagital backward movement in upper dentition, about 2.5 mm in 1.5 month test group and more obvious sagital backward movement in both upper dentition and maxilla in 3 month test group. The vertical and horizontal positions did not change obviously in both upper dentition and maxilla.ANS-PNS plane rotated clockwise slightly. 0.98° in 1. 5 month test group and 1.39° in 3 month test group respectively. Conclusion: Zygomatic miniplate implants can be utilized as the stable and effective anchorage not only to inhibit maxilla from growing forward but also to retract maxilla distally with slight rotation.%目的:运用螺旋CT三维重建评价颧骨种植体支抗向后牵引猴上颌骨对颅颌面三维方向的矫形作用.方法:选用生长发育期恒河猴4只,3只用于研究(1只牵引1.5月、2只牵引3月),1只作为对照;实验前后分别行CT扫描及三维重建,测量各标志点的变化,分析颅颌面三维方向的矫形作用.结果:与对照组相比,1.5月组主要表现为上牙弓矢状向的变化,后移约2.5 mm,垂直向、水平向均无明显变化;3月组上牙弓矢状向变化更为明显,后移约3.8 mm,上颌骨后移约2.5 mm.硬腭平面相对于前颅底平面发生轻度顺时针旋转,1.5月时为0.98°,3月时为1.39°.结论:颧骨微钛板种植体支抗能有效后牵引上颌骨及上牙弓、抑制上颌矢状向发育,垂直向及水平向改变不明显.

  14. 重复荷载作用下钢筋混凝土锚固端黏结性能试验研究%Test study on bonding performance of reinforced concrete anchorage zone under repeated loads

    Institute of Scientific and Technical Information of China (English)

    蒋德稳; 邱洪兴

    2012-01-01

    通过对23个钢筋混凝土试件的静载和重复荷载作用下拔出试验,研究了重复荷载作用下钢筋峰值应变和残余应变、自由端和加载端滑移发展特征,得到了重复荷载作用下黏结应力-滑移滞回曲线变化规律。运用试验测定的钢筋应变,计算了静载和重复荷载作用下锚固端黏结应力分布曲线,总结了重复荷载作用下峰值黏结应力、残余黏结应力变化特征,分析了锚固端黏结应力分布机理。研究结果表明:重复荷载作用后黏结强度并不受重复次数影响;重复荷载作用下,自由端、加载端峰值滑移量和残余滑移量发展均符合疲劳破坏的三阶段特征;当滑移量累积到静载作用下破坏时的峰值滑移量时,发生黏结疲劳破坏;随着重复次数的增加,黏结应力沿锚固长度的分布出现明显的双峰现象,最大黏结应力位于距离加载端和自由端约1/4锚固长度位置处。研究结果可为深入研究混凝土结构疲劳性能提供依据。%23 reinforced concrete Rebar' s peak and residual stress, pull-out specimens were tested under monotonic loading and repeated loading peak slip and residual slip at the loading end and free end were inspected in this test. The bonding stress-slip hysteretic curve was obtained. According to the rebar stress data, the distribution curve in the anchorage was calculated under monotonic loading and repeated loading. Variation characteristics of peak and residual bonding stress under repeated loads were summarized, and bonding stress distribution mechanism was analyzed. Research result shows that bonding strength is not influenced much by repeated loading. The peak slip and residual slip follow the three stage rule of fatigue failure. Bonding fatigue failure occurs when the rebar slippage under repeated loading reaches the maximum slippage under monotonic loading. With the increase of repeating times, the obvious double peak phenomenon was shown in

  15. 组合支抗种植体在下颌严重舌倾磨牙矫治中的应用%Pilot study on efficiency of connected miniscrews as anchorage for correction of lingual tipping lower molar

    Institute of Scientific and Technical Information of China (English)

    毛慧霞; 李峰; 元志昌; 李玮; 邱小亮; 武建潮

    2015-01-01

    目的:评价利用组合支抗种植体竖直下颌舌倾磨牙的临床效果.方法:5例下颌磨牙严重舌倾患者,在舌倾磨牙同侧前磨牙区植入两枚微型种植体,取1段0.48mm×0.64mm不锈钢方丝,用釉质粘结剂将其固定于种植体头部,使两颗种植体连接成为一个整体,并且使不锈钢方丝一端位于舌倾磨牙的颊侧根尖水平处,弯折使其形成牵引钩,方便钩挂皮圈.在舌倾磨牙牙合面粘结舌侧扣,用链状皮圈连接舌侧扣和牵引钩,使橡皮圈产生1N力,颊向倾斜和压低舌倾磨牙.结果:所有支抗种植体植入顺利,在治疗过程中能行使支抗功能,未出现松动脱落.经5个月左右的治疗,5例患者舌倾的下颌磨牙均和对合牙形成良好咬合.磨牙舌倾得到矫正,未见明显松动,且颊舌向转矩正常,也未发现明显的牙根吸收与牙髓坏死,牙周状况良好.结论:应用组合支抗种植体能有效地矫正严重下颌舌倾磨牙.%Objective To study the efficiency of connected miniscrews as anchorage for correction of lingual tipping lower molar. Methods 4 patients with severe lingual tipping lower molar were selected.Two miniscrews were placed on the buccul alveolar closed to the lingual tipping molars. 1 straight 0.48mm × 0.64mm orthodontic stainless steel archwires were welded.The distal ends of the wires were bent to form hooks stretching to the buccal sides of the tipping molars at the apical level. The stainless steel archwire was fixed to the heads of the two implants with light cured resin to make the two implants together as anchorage for lingual tipping molar intrusion. Results All the miniscrews were successful and there was no tooth mobility in the treatment.After 4-5 months' treatment,lingual tipping molars were corrected.No obvious mobility was observed on the molars after treatment.The periodontal condition was well kept.There was no elongaion,no obvious root resorption or pulp necrosis. Conclusion Lingual

  16. 片段弓技术结合上颌微螺钉支抗矫治前牙拥挤%Treatment of anterior crowding with maxillary mini-screw anchorage and class Ⅲ elastic traction

    Institute of Scientific and Technical Information of China (English)

    李正明; 刘新强; 黄永谦; 肖芦靖

    2012-01-01

    目的:评价应用片段弓技术结合上颌微螺钉支抗配合Ⅲ类颌间牵引非拔牙矫治单纯前牙拥挤的临床效果.方法:12例单纯前牙拥挤病例,应用片段弓技术,上颌颧下嵴微螺钉支抗配合Ⅲ类牵引拉后牙段向远中,待间隙足够时排齐前牙,对矫治前后的模型及X线头颅侧位片进行测量分析.结果:U1/SN、U1/NA、L1/NB和IMPA均无明显变化,结论:后牙片段弓结合上颌微螺钉支抗可以在保持前牙唇倾度不变甚至轻度内收的情况下排齐拥挤的牙列.%Objective: To evaluate the clinical effects of maxillary mini-screw anchorage and ClassⅢ elastics on non-extraction treatment of anterior crowding. Method: 12 cases of anterior crowding were treated with segmental arch technique and Mini-screws were inserted into the maxillary infrazygomatic crest (IZC) area to pull the posterior segment distally, class Ⅲ traction was used to the distal movement of mandibular posterior teeth. Anterior teeth were aligned until adequate space of front segment was obtained. Model and cephalometric X ray film were examined before and after treatment. Result: The width of upper and lower arch was increased significantly. No significant changes were seen on the angles of Ul / SN, Ul / NA.L1 / NB and IMPA. Conclusion:To those anterior crowding cases.application of segmental arch technique combination with maxillary micro-screw anchorage and Class Ⅲ traction can correct the crowing when the torque of anterior teeth was maintained. The method is suitable for mild to moderate skeletal type I crowding cases.

  17. 钛合金/不锈钢微植体支抗稳定性的组织学研究%Histological study on the stability of titanium alloy and stainless steel microimplant anchorage

    Institute of Scientific and Technical Information of China (English)

    许志强; 史建陆; 任继业; 林艺翚; 魏小平

    2012-01-01

    Objective: To evaluate the stability of titanium alloy and stainless steel microimplant anchorage after immediate loading. Methods: One titanium alloy microimplant and one stainless steel microimplant were placed in one side of maxilla and the other side of mandible respectively in eight adult male mongrel dogs at random. 1.96 N of constant force was loaded immediately between two micro-implants in maxilla or mandible. Four dogs were sacrificed 4 and 12 weeks respectively after operation. Undercalcified sections longitudinal to the implants were made for histological observation and measurement of the bone contact ratio( BCR) between microimplant and bone interface. Results: All microimplants kept stable. The microimplants had favorable biological consistencies with the fiber and bone around them. The BCR increased with the healing time prolonged. The BCR of titanium alloy group was higher than that of stainless steel group. Conclusion: The healing mode of both microimplants is fibro-osseous integrations when immediate loading is applied. The titanium alloy microimplant is more stable than the stainless steel microimplant as an orthodontic anchorage.%目的:评估钛合金和不锈钢微植体支抗即刻负载的稳定性.方法:选用8只本地成年雄性犬,每只犬任选一侧上颌骨和对侧下颌骨各植入1枚钛合金和不锈钢微植体.同颌2枚微植体间即刻加载1.96 N的力.4周和12周时各随机处死4只实验犬,制作硬组织切片进行组织学研究.结果:所有微植体均没有松动、脱落.微植体与周围组织有良好的生物相容性,种植体周围有纤维组织和骨组织共同包绕.骨结合率随着愈合时间的延长而增高,钛合金微植体骨结合率高于不锈钢微植体.结论:即刻负载下,钛合金和不锈钢微植体支抗的愈合形式都是纤维骨性结合,均可保持稳定,钛合金微植体更为稳定.

  18. 既有无黏结预应力混凝土楼盖改造钢绞线重锚施工技术∗%Construction of Strand Again Anchorage for Concrete Prestressed Floor Reconstruction with Unbonded Tendons

    Institute of Scientific and Technical Information of China (English)

    陈浩; 刘玉辉; 陈维超; 黄伟

    2014-01-01

    以长沙汇源大厦裙楼部分拆除改造工程为对象,从现场试拆除试验、主体结构重锚端部加固梁、楼盖开洞、梳形锚垫板安装、开口式锚具安装、无黏结预应力钢绞线切断、现场监控等技术要点介绍了既有无黏结预应力混凝土楼盖改造钢绞线重锚施工关键技术。采用一种新型开口式钢绞线锚具,确保了拆除过程中的无黏结预应力筋的安全截断及可靠再锚固,使结构中被保留的预应力筋的应力不损失或损失很少,无需二次张拉。监控结果表明:在拆除改造过程中,楼板的应变、位移满足正常使用条件要求,整体结构也没出现倾斜现象,采用该技术确保了整体结构的安全性。工程实践结果表明,该方法取得了良好的效果。%Based on the dismantlement reconstruction engineering of partially podium building of Huiyuan building in Changsha, the technical points of field test on dismantlement, strengthening beam of again anchorage end region,opening in floors,comb anchor plate,open type anchor,blanking, monitoring of the key construction technology of strand again anchorage of concrete floor prestressed transformation with unbonded tendons were introduced. A new open strand anchor is used to ensure the safety blanking and reliable re-anchoring of unbonded tendons in the demolition process,the stress of preservation tendons is no loss or few losses without secondary tensioning. Monitoring results showed that the strain and displacement of floor met the requirements of normal using conditions in dismantlement reconstruction process,the inclined phenomenon of whole structure did not appear, the security of the whole structure was ensured with the technology. Engineering practice showed that this technology obtained a good effect.

  19. 微种植支抗正畸矫正下颌磨牙重度阻生1例%Micro implant anchorage clinical success in orthodontic treatment of deeply impacted mandibular molar

    Institute of Scientific and Technical Information of China (English)

    杨洪; 谢德林

    2011-01-01

    Impaction of both first permanent molar and second permament molar in lower mandible is rarely Treatments depend on the degree of molar inclination, the position of first molar and second molar, the classification of bite(Angle's I classification), the position and the appearance of third molar. A case of successful uprighting a severely impacted right mandibular first molar using a micro implant anchorage,fixed appliance and oral surgical procedures is presented. Methods include surgical extraction of an impacted second molar and acceptabie mesial movement of third moar which would move to the position of second molar.%下颌第一、第二恒磨牙同时阻生罕见.矫治时需根据第一、第二磨牙的位置及倾斜程度、咬合关系,第三磨牙的形态位置决定治疗方案.本文报告1例下颌第一、第二磨牙阻生病例安格尔Ⅰ类,手术拔除第二磨牙,运用微种植支抗、固定矫治器和口腔外科手术等方法使第一磨牙萌出,第三磨牙向近中移动代替第二磨牙行使功能,取得了较为满意的治疗效果.

  20. The clinical practice with the carriere distalizer and microscopic implant anchorage during teeth backwards movement%远中移动棒结合种植体支抗移动上颌牙列的临床应用

    Institute of Scientific and Technical Information of China (English)

    尹玉承; 兰泽栋; 张鹏

    2011-01-01

    目的:探讨正畸矫治中远中移动磨牙的有效方法.方法:对21例安氏Ⅱ错患者采用远中移动棒与微种植体支抗有机结合,远中移动上颌磨牙的方法,观察其矫治后磨牙关系的改变情况.结果:患者的上颌磨牙均实现有效远移,解除上颌牙列的拥挤,达到Ⅰ类关系.结论:应用远中移动棒结合微种植体支抗可以有效解除牙列的拥挤,为牙列拥挤的非拔牙矫治提供了一种新方法.%Objective: To discuss the effective treatment method during upper teeth backwards movement in clinical practice. Methods: Make upper teeth backwards with CD appliance combined MIA as anchorage for 21 patients of Angel Ⅱocclusion, to observe the change of molar teeth. Results: Upper molars have achieved backwards movement effectively,relieved crowded of upper teeth, reached class Ⅰ or over-class Ⅰ relations. Conclusion: Practice with CD appliance and MIA together in clinical can achieve teeth backwards effectively, is a new technic curing teeth crowded beyond nonextraction treatment.

  1. Experimental study on bond and anchorage behavior of glued-in rebar in glulam%胶合木植筋黏结锚固性能试验研究

    Institute of Scientific and Technical Information of China (English)

    凌志彬; 杨会峰; 刘伟庆; 陆伟东

    2013-01-01

    This paper describes an experimental program of 25 glulam specimens with glued-in rebar which aim to investigate the influence of slenderness ratio (λ =la/d) of rebar and glue-line thickness on the pull out load,and bond behavior of glued-in rebar axially loaded parallel to the grain.The failure modes and mechanics of specimens were analyzed.Moreover,in order to obtain the bond stress distribution along the anchorage length of rebar,specimens with strain gauges attached to steel rebar internally were designed.The experimental results show that failure occurs mainly due to pull-out of rebar,shear failure of timber around the glue-line,splitting of timber and yielding of rebar.The pull out load of glued-in rebar increases with the increasing of both the anchorage length and glue-line thickness.The ductile failure of yielding rebar occurs with the slenderness ratio of rebar up to 12.5.Anchorage length and glueline thickness have obvious influence on the bond behavior of glued-in rebar.The distribution of bond stress at rebar/adhesive interface is not uniform,but rather accentuated near both the loading end and the anchorage end,which confirms the theory of Volkersen (1938).The variation of bond stress at rebar/adhesive interface is different from adhesive/timber interface with the increasing of glue-line thickness.With glue-line thickness increased from 2 mm to 6 mm,bond stress at rebar/adhesive interface increases,while decreases at adhesive/timber interface.Appropriate increasing of glue-line thickness is beneficial to the decreasing of peak value of bond stress.%对25个胶合木植筋(带肋钢筋)试件进行对拉试验,研究植筋长细比(λ=la/d)及胶层厚度对胶合木植筋的连接承载力及界面黏结性能的影响,并对试件的破坏形态和破坏机理进行分析.为获得胶层界面黏结应力的分布,设计钢筋内贴片试件进行试验.结果表明,试件的破坏形态主要有钢筋拔出、木材环向剪切、木材劈裂、

  2. 三段弓技术与微种植支抗技术压低和内收上切牙效果的对比研究%Comparison of the Simultaneous Intrusion and Retraction Effect on the Maxillary Incisors between Three Pieces Arch Wire Technique and Miniscrew Anchorage.

    Institute of Scientific and Technical Information of China (English)

    王旭; 张栋梁; 王锐

    2011-01-01

    目的:对比两种不同技术-三段弓技术与微螺钉支抗滑动技术,在正畸治疗过程中产生的牙齿以及骨骼的效应差异.方法:对三段弓技术组的18例患者以及微螺钉支抗组的19例患者均进行切牙的内收和压低,分析测量所有患者的头颅定位侧位片以评估两种技术的差异.在水平和垂直方向上对两组患者上颌第一磨牙的移位和相对骨骼改变进行分析.同时在根尖周X光片上对牙根吸收进行测量.结果:U1-SN(P<0.05),覆盖、覆、PP-U1、U1水平移动(P<0.01),UL-U1(P<0.05),在三段弓组和微螺钉支抗组均有明显减小.然而,在三段弓组,U6角度(P<0.01),MP-SN、PP-U6(P<0.05)和U6水平移动(P<0.05),与微螺钉组相比均有显著增加.两组的治疗周期及牙根吸收率无显著性差异.结论:采用反Spee曲线弓丝的微螺钉支抗滑动技术,被证明是有效地的内收并压低上颌前牙的口内支抗增强装置.与三段弓技术相比,微螺钉技术在水平(前后向)或垂直方向均未见支抗丧失.%Objective: To compare the dental and skeletal effect of two ditferent techniques, three-piece arch wire technique and miniscrew anchorage sliding mechanics. Methods: Lateral cephalometrie radiographs from 18 patients in the three-piece arch wire group and 19 patients in the minserew anchorage group were analyzed for incisor retraction and intrusion. The upper 1st molar displacement and the relative skeletal changes were analyzed in the horizontal and vertical directions in both groups. Root resorption was also measured on periapical radiographs. Results:Significant reduction of U1-SN(P<0.05) ,overjet, overbite, PP-U1(P<0.01), U1 horizontal(P<0. 01), UL -U1 (P<0.05) were observed in both groups, the three-piece arch wire group and miniscrew anchorage group.However, there were significant increases in U6 angle (P < 0. 01 ), MP - SN, PP - U6 (P < 0. 05), and U6Horizontal(P<0.05) in the three-piece arch wire group

  3. 个体化弓丝和横腭弓联合强化支抗的临床应用%The effect of anchorage enforcement of customized archwire integrated with TPA-A preliminary clinical study

    Institute of Scientific and Technical Information of China (English)

    陈荣敬; 胡铮; 沈刚

    2009-01-01

    Objective This study was designed to examine the effect of the custom-bent archwire in enforcing molar anchorage during canine and /or incisal retraction.Methods 24 female adult patients diagnosed with Class Ⅰ with severe crowding or Class Ⅰwith moderate crowding and proclined upper incisors,were included into this study.The age of the patients ranged from 18 years 8 months to 25 years 5 months.As required by treatment plan, hte patients were extracted uppe &lower premolars to relieve crowding and retract frontal teeth. The upper starting archwire of 0.018ss was custom-bent with its first order bends fitting to the irregularities of the upper dentition,so that it was engaged into the brackets passively.The transpalatal Arch(TPA) was also placed transversely connecting bilateral molars.Canine disalzation was implemented firstly using ligature wire lace-back then active power-chain elastics.Study models and cephalograms were taken before and after orthodontic treatment and the parameters,namely,Ptm-6,S0-6AP and 6-PP were measured to indic ate the displacement of the molars.Results (1)Althouth the increase in Ptm-6 and So-6AP was significant(P0.05),indicating a good control of the molars even in vertical dimension.Conclusions A combined use of custom-bent archwire with TPA enhances molar anchorage.%目的 评价安氏Ⅰ类错(牙合)矫正治疗中个体化弓丝和横腭弓联合应用的支抗控制效果.方法 选择18岁8个月至25岁6个月安氏Ⅰ类错(牙合)女性患者24例,分析个体化弓丝和横腭弓联合应用加强支抗治疗前后的X线头影测量值的变化.结果 Ptm-6与So-6AP虽有增大(P<0.05),但支抗磨牙的前移量不到拔牙间隙的1/5;6-PP、MP-FH及ANS-Me治疗前后均无显著性改变(P>0.05),支抗磨牙在垂直方向上也得到了有效的控制;水平方向上无支抗磨牙的舌向倾斜及近中舌向扭转.结论 个体化弓丝和横腭弓联合应用能有效地稳定支抗磨牙.

  4. Nance弓在排齐整平阶段增强支抗的三维评价%Three-dimensional analysis of anchorage control in alignment and leveling stage with Nance appliance

    Institute of Scientific and Technical Information of China (English)

    高琳; 李巍然; 林久祥

    2010-01-01

    Objective To evaluate the anchorage loss in first premolar extraction cases with Nance appliance three-dimensionally during the leveling and alignment stage. Methods Forty-one orthodontic patients were selected. Enrollment criteria included moderate to severe crowding and extraction of upper first premolars. The patients were randomly divided into two groups. Twenty cases without anchorage control served as control group and 21 cases with Nance appliance served as experimental group. Lateral cephalograpms and study casts were collected before treatment and at the end of leveling and alignment stage. The dental casts were scanned with LPX-1200 three-dimensional laser scanner and analyzed using three-dimensional reverse modeling software program (Rapidform 2006(R)). Statistical analysis was performed using software package Spss 10.0. Results No significant difference was found in upper incisor inclination between control group and the experimental group. Significant difference was found in sagittal displacement, transverse movement and the rotation control of upper first molars between experimental and control groups. Conehtsions Nance appliance was effective in controlling sagittal displacement, transverse movement and rotation of the upper first molars.%目的 评价直丝弓矫治器排齐整平阶段Nance弓加强支抗的三维表现.方法 选择中度以上拥挤,上颌减数双侧第一前磨牙的患者41例,随机分组,20例不用辅助支抗装置作为对照组,21例粘Nance弓作为Nance组.排齐整平前后取模型并拍头颅侧位片.模型用Roland LPX-1200三维点激光扫描仪数字化,使用测量软件(Rapidform 2006(R))处理分析治疗前后上颌第一磨牙各牙尖标志点三维向上的线距及磨牙角度变化.并对头颅侧位片的前牙变化进行测量.应用SPSS10.0统计软件对测量结果行统计学分析.结果 两组患者排齐整平阶段前牙唇倾控制没有显著统计学差异.在矢状向、横向及扭转

  5. Measurement of incisor root resorption by CBCT in treatment of gummy smile using implant anchorage%种植支抗治疗露龈笑过程中切牙牙根吸收的CBCT检测

    Institute of Scientific and Technical Information of China (English)

    吴碧蓉; 骆英; 王晖

    2014-01-01

    目的:通过 CBCT技术精确测量种植支抗治疗露龈笑过程中所导致的上颌切牙牙根吸收的情况。方法11例患者全部采用直丝弓矫治技术,在上颌两侧侧切牙和中切牙之间的牙槽骨上,各植入1枚微螺钉,每侧约0.98 N 压低上前牙。当龈缘距与微笑线基本平齐时,治疗停止,进入保持阶段。治疗前后拍摄 CBCT,在矢状位图像选取牙根长度最长的轴面进行长度测量。结果所有患者露龈笑均有明显改善,平均减小(2.47±0.64)mm,切牙压入量为(2.81±0.62)mm。CBCT显示,治疗前后切牙牙根有一定程度的吸收,其中中切牙的吸收量大于侧切牙,但没有统计学意义。结论采用种植支抗治疗露龈笑会导致上颌切牙出现牙根吸收,CBCT能够定量测量根吸收的情况。%Objective To measurethe incisor root resorptionquantitatively by CBCT in the treatment of gummy smile by using implant anchorage.Methods The straight wire appliance technology was used for 1 1 cases.Mini -screw implants were inserted between the central and lateral incisors.100 g force was used for the intrusion of incisors.Treatment stopped and maintainence began when the gingi-val margin flushed with smile line.CBCT images of all patients were taken immediately before and after intrusion.The measurement of the root length was from the longest axis on the saggital plane.Results Significant improvement of gummy smile was found in all ca-ses,and the average decrease was (2.47 ±0.64)mm.The intrusion of incisors was (2.81 ±0.62)mm.CBCT showed that the resorp-tion was more in central incisors than that in lateral incisors.Conclusions Root resorption occurred in the treatment of gummy smile by using implant anchorage,and CBCT can measure root resorption quantitatively.

  6. 斜拉桥索塔锚固区前壁竖向拉-压杆模型%Vertical STM in Facade Wall of Pylon Anchorage Zone of Cable-stayed Bridge

    Institute of Scientific and Technical Information of China (English)

    陶齐宇; 刘扬

    2011-01-01

    To the tendon anchorage system in the wall of box pylon of cable-stayed bridge, the facade wall of cable-anchored pylon was researched using strut-and-tie model ( STM). According to the optimization principle of STM, the STM of single anchor was established by means of force method. On the basis of the STM of single anchor, the STM in the facade wall was preliminary built. The expression of internal force in ties about z, the vertical distance between the tie T3 and node 1, was established. Using topology optimization result (T2 = 0) and Cardan Formula, the value of z was determined, the STM in the facade wall was comprehensively solved. Thus, the distribution of compressive and tensile stresses in the facade wall under the action of vertical component of cable force was accurately reflected. Finally, through researching the pylon of Yibin Yangzte River Bridge, the parameter α3 =23.3° was proposed, and the STM in the facade wall was simplified. It has better precision and can be used to determine tendon specification in the anchorage zone of box pylon.%对斜拉桥箱形截面索塔塔壁预应力锚固体系,采用拉-压杆模型方法对拉索直接锚固的塔柱前壁进行研究.以力法为手段,依据拉-压杆模型的优化原理,确立了体内单锚的拉-压杆模型.以单锚拉-压杆模型为基础,初步构建前壁的拉-压杆模型.取z为拉杆(T3)与结点(1)间的竖向距离,采用力法建立以z为函数的拉杆内力的表达式,利用拓扑优化成果(T2=0)和卡尔丹公式,确定z的数值,自下而上全面解答了前壁的拉-压杆模型,从而准确反映在拉索竖向分力作用下前壁拉、压应力的分布状况.最后,通过对宜宾长江大桥索塔的实例研究,提出α3= 23.3°,简化了前壁拉-压杆模型,且具有较好的工程精度,可用于确定索塔锚固区的预应力筋的规格.

  7. Experimental Study of Anchor Tensile Plate Cable Anchorage System in Concrete Girder of Actual Bridge%锚拉板式混凝土索梁锚固体系实桥试验研究

    Institute of Scientific and Technical Information of China (English)

    石雪飞; 周军勇; 胡可; 阮欣

    2016-01-01

    为研究索力作用下锚拉板式混凝土索梁锚固体系的受力性能,以五河淮河大桥为工程背景进行实桥试验和有限元分析。选取该桥0号节段混凝土锚拉板进行实桥试验,测试锚拉板在分级索力作用下的应力及变形,采用ANSYS软件建立有限元模型,计算2种连接方式下(考虑混凝土主梁与钢锚拉板的固结与滑移)的应力分布与锚拉板变形。结果表明,钢锚拉板与混凝土主梁在固结或滑移连接方式下,斜拉索锚固区域的应力分布基本相同,但连接区域的应力分布及锚拉板变位差别显著;测试的锚拉板应力和位移与荷载呈现良好线性相关性,最大测点应力296 M Pa ,结构仍处于弹性工作状态;锚拉板应力分布的实测值与有限元计算值吻合,板件应力扩散和传递效果良好;连接区域的实测应力和位移与滑移方式下的有限元分析较吻合,但摩擦系数不主导滑移结果。%To study the mechanical performance of the anchor tensile plate cable anchorage system in concrete girder under the action of the cable tension ,the test and finite element analysis of the steel anchor tensile plate stay cable anchorage system in the concrete main girder of the actu‐al bridge of Wuhe Huaihe River Bridge were carried out .The anchor tensile plate in the segment No .0 of the main girder of the bridge was selected and tested .The stress and displacement of the anchor tensile plate under the different levels of the stay cable tension were measured .The finite element model for the anchor tensile plate was set up ,using the software ANSYS and the stress distribution and the anchor tensile plate displacement under the 2 kinds of the connecting ways (the rigid fixity and sliding connecting of the anchor tensile plate with the concrete main girder ) were calculated .The results show that under the connecting ways of the rigid fixity or sliding connect‐ing of the anchor

  8. 南京长江四桥北锚碇工程锚体及锚固系统施工技术%Construction Technology of Anchor and Anchor System for North Anchorage Engineering of the Fourth Nanjing Yangtze River Bridge

    Institute of Scientific and Technical Information of China (English)

    葛文璇; 徐贵娥; 陈静

    2012-01-01

    悬索桥的锚碇是一个十分重要的部位,以南京长江四桥北锚碇工程为背景,介绍了锚体及锚固系统的施工工艺.南京长江四桥锚碇锚固系统采用钢筋混凝土榫锚固系统,以提高结构的可靠性和耐久性.从锚体的分层分块、模板施工和混凝土浇筑工艺方面介绍了锚体施工工艺,并从锚固钢板的加工、起吊、安装、精确定位等方面介绍了锚固系统的施工工艺.%The anchorage caisson is a very important part of suspension bridge. The authors introduce the construction technology of anchor and anchor system of north anchorage of the Fourth Nanjing Yangtze River Bridge. The mortise-tenon anchor system of reinforced concrete is adopted in the anchor system of north anchorage of the Fourth Nanjing Yangtze River Bridge in order to improve its reliability and durability. The authors introduce the construction technology of anchor from anchor of hierarchical blocks, formwork and concrete pouring technique. From the anchor plate processing, hoisting, installation and precise positioning, the author introduce the construction technology of anchor system.

  9. Effect of micro implant anchorage loading on estrogen and progesterone in pregant rat%微种植体支抗负载对妊娠大鼠雌激素和孕激素的影响

    Institute of Scientific and Technical Information of China (English)

    杜伟; 张彬; 温黎明; 李金源

    2015-01-01

    Objective To establish the pregnant rat model for investigating the effect of the orthodontic micro implant anchorage loading on estrogen and progesterone .Methods 30 female rats were randomly divided into three groups :the normal group ,pregnancy group and pregnancy loading group .The left tibia was implanted by 2 micro im‐plants .The levels of estrogen and progesterone were detected by collecting blood sample via abdominal aorta ,and at the same time the right tibia bone mineral density was detected .Results The estrogen level in the pregnancy group and the pregnancy loading group were higher than that in the normal group with statistical difference(P<0 .05) , while the progesterone level was higher than that in the normal group ,the difference was statistically significant(P<0 .05) .The bone mineral density in the pregnancy group was lower than that in the noma group(P<0 .05) .Conclu‐sion When exerting 60g orthodontic light force during pregnant period ,the levels of estrogen and progesterone in rats will decrease .The bone mineral density decreased during pregnant period .%目的:建立妊娠大鼠模型,探讨正畸微种植体支抗负载对妊娠大鼠孕激素、雌激素的影响。方法30只雌性大鼠分为正常组、妊娠组、妊娠加力组,左侧胫骨植入微种植体2枚,腹主动脉采血检测孕激素、雌激素,同时检测右侧胫骨骨密度。结果妊娠组、妊娠加力组大鼠雌激素水平高于正常组,差异有统计学意义(P<0.05);孕激素水平高于正常组,差异有统计学意义(P<0.05);妊娠组大鼠骨密度低于正常组,差异有统计学意义(P<0.05)。结论妊娠阶段施加60 g正畸轻力时大鼠雌激素、孕激素会稍有下降,妊娠阶段骨密度下降。

  10. 南京长江四桥南锚碇基坑渗流控制方案研究%Study on Seepage Control Scheme for Foundation Pit of South Anchorage of 4th Nanjing Yangtze River Bridge

    Institute of Scientific and Technical Information of China (English)

    肖利; 王连新; 潘霄; 张家发

    2009-01-01

    The foundation pit for the south anchorage of 4th Nanjing Yangtze River Bridge is protected with concrete diaphragm wall. The wall will be embedded in the medium-weathered layer with 3 meters. Because the dredging layer at the wall bottom and the strongly weathered rock are more permeable than the wall, under-ground water may flow through the dredging layer to the foundation pit. On the basis of numerical simulation with 3D seepage field model, the permeability sensitivity is analyzed and the seepage control efficiency is compared among different designs. The results indicate that the thickness and permeability of medium-weathered layer influence the discharge and seepage stability of the pit significantly, that under cases without curtain grouting in the bed-rock, the seepage gradient in the dredging layer is high and seepage deformation might occur, and that under cases with curtain grouting , the discharge would be much lower and the stability of foundation pit would be ensured.%南京长江第四大桥南锚碇基础采用井筒式地连墙结构形式,地连墙嵌入中风化层约3m,下部可能形成沉渣层,且强风化层裂隙较多,局部透水性较好,地下水可能通过沉渣层及裂隙绕渗进入基坑.建立三维模型模拟基坑渗流场,通过参数敏感性分析和方案对比表明:中风化层厚度及渗透性对基坑的渗流量及渗透稳定性有明显影响;基岩无灌浆帷幕条件下,地连墙底面沉渣层渗透比降过大,可能引发渗透变形问题;对基岩进行帷幕灌浆后,可有效减小基坑渗流量,使基坑渗透稳定性得到保障.

  11. Stress analysis of mutated Class Ⅱ intermaxillary traction system to mandibular anchorage teeth%改良型Ⅱ类颌间牵引致下颌支抗牙受力变化分析

    Institute of Scientific and Technical Information of China (English)

    程自力; 刘长庚; 莫业跃; 赵殿才; 尹高权; 黄小芳

    2012-01-01

    Objective To explore the stress and movement feature of anchorage molars result from mutated Class II intermaxillary traction, and to analyse the related influencing factors. Methods Refers to the Model Typodont's principle and the simplified appliances to measure the experimental teeth mechanical force and movement were designed and made. According to the differences of the loading points, strength and angle of the force, the objective teeth were separated into four experimental groups, and each one had three samples. Group I : loading points were at the level of mesiolin-gual cusp; the upper loading points were at the level of maxillary canine teeth; the force was 30 degree and 150 gram. Group II ; loading points were at the level of distolingual cusp, upper loading points were at the level of maxillary canine teeth; the force was 30 degree and 150 gram. Group III : loading points were at the level of mesiolingual cusp, upper loading points were at the level of maxillary canine teeth; the force was 30 degree and 100 gram. Group IV: loading points were at the level of mesiolingual cusp, upper loading points were at the level of maxillary prcmolar; the force was 60 degree and 100 gram. The mesiobuccal cusp, mesiolingular cusp, disdal cusp and distolingular cusp' s highest points of the experimental teeth were chosen as fixed index points, and the benchmark lines of the measure equipment as the reference point lines, and then the distances between index points and benchmark lines before and after the experiments were measured. Results Under the traction force, all the testing teeth showed clear mesial movement (the value of dot a and b, which represents the mesial displacement, was 0. 50 mm and 3.33 mm respectively) and buccal movement (the value of dot c and d, which represents the buccal displacement, was 2.67 mm and 6. 17 mm respectively) , and were oc-clusally elongated {the value of dot g and h, which represents the vertical displacement, was 0. 22 mm and 4. 00

  12. 种植体支抗后牵引上颌骨颅颌面结构变化的动物实验研究%Dentofacial changes after maxilla retraction with zygomatic implant anchorage-a rhesus monkey study

    Institute of Scientific and Technical Information of China (English)

    张晓蓉; 曾祥龙; 徐芸

    2009-01-01

    Objective To study the dentofacial changes caused by retractive force with zygomatic implant to the maxilla of rhesus monkeys.Methods 4 yound male rhesuses were employed,3 experimented(1 for 1.5 month and 2 for 3 months),and 1 as control.Titanium miniplates were fixed on the bilateral zygomatic bones as an anchorage,the maxillary cast splint was anchored in cisors,second deciduous molars and firsr molars.A retractive force of 150g was exerted on each side with a direction parallel to an occlusal plane.Cephalometric Comparison was analysed between the beginning and the end of experiment.Results A point was moved backward as measured by A-OLP distance,which was decreased by 1 mm(1.5M)and 2.5 mm(3M).SNA angle was decreased by 1 degree(1.5M) and 3.5 degree (3M).SNA angle was decreased by 3.5 mm(1.5M) and average 6.25 mm(3M) with the ratio of skeletal to dental effects 2.5:1(1.5M) and 1.8:1(3M); the molar occlusal changes were found to develop 5 mm distalization with the ratio of skeletal to dental effects 5:1(1.5M) and 4:1(3M);maxillary effects stronger than mandibular effects in the ratio of 2.5 to 1(1.5M) and 5.7 to 1 (3M).Conclusions Zygomatic implant can be utilized as an anchorage not only to inhibit maxilla from growing forward but also to retract maxilla distally with som counter-clocwise rotation.%目的 评价种植体支抗后牵引上颌骨对颅颌面的矫形作用.方法 生长发育期恒河猴4只,3只用于研究(1只牵引1.5月、2只牵引3月),1只作为对照;采用颧骨微钛板种植体支抗后牵引上颌骨,铸造固位夹板粘接于上颌第一恒磨牙、第二乳磨牙及切牙上,牵引力值每侧1.47 N(150克),方向与(牙合)平面平行;对实验前后X线头影测量进行对比分析.结果 实验动物A点后移,1.5月组1mm,3月组平均2.5 mm;SNA减小,1.5月组1°,3月组平均3.5°.1.5月组前牙覆盖减小3.5 mm,其中骨效应大于牙齿效应(2.5:1);磨牙关系改变为3 mm,骨效应大于牙齿效应(5:1);

  13. BONE ANCHORAGE PENDULUM STUDY ON DIGITAL CASTS

    OpenAIRE

    Gregolin, Paula Rotoli

    2009-01-01

    A distalização dos molares superiores é uma opção de tratamento da má oclusão de Classe II, quando o envolvimento é principalmente dentoalveolar. Dispositivos intrabucais como o aparelho Pêndulo, dispensam a colaboração do paciente quanto ao uso, porém promovem efeitos muitas vezes indesejáveis como a vestibularização dos dentes anteriores que participam na ancoragem e a inclinação dos molares distalizados. Após o surgimento dos Dispositivos de Ancoragem Temporária (DATs), como o min...

  14. 76 FR 59596 - Anchorage Regulations; Newport, RI

    Science.gov (United States)

    2011-09-27

    ... cruise ship visits to Newport and to improve navigation safety. DATES: Comments and related material..., Rhode Island, to better accommodate increasing cruise ship visits to Newport, and to improve navigation... years cruise ship visits to Newport, RI, have been more frequent. On occasion, there is a need to...

  15. Comparative study of clinic effects of segmental archs and mini-implants for orthodontic anchorage on orthodontic canine distalization%片段弓与微种植体支抗拉尖牙向远中的临床应用对比研究

    Institute of Scientific and Technical Information of China (English)

    徐晓静; 沈云娟; 秦燕军

    2012-01-01

    Objective To compare the clinic effects of segmental archs and mini-implants for orthodontic anchorage on orthodontic canine distalization. Methods 60 cases of dental crowding, whose four first premolars were extracted and canine distalization was needed according to the treatment protocol, were randomly divided into 2 groups. Mini-implants were used in the cases in experimental group as orthodontic anchorage to move canine distally, and segmental archs were used in the control cases. The distances of canine dis-talizalion and the angles of anchorage molar inclination in 60 cases were measured and compared. Results The mean velocity of canine distalizalion in the experimental group was (1.428 ±0.072) mm/month,which was faster than(l. 137 ±0.081)mm/month in the control group. The degree of molar inclination (1.27 ±0.18) in the experimental group was less than that in the control group (1.91 ±0.13). Statistic analysis showed that there were significant differences. Conclusions The mini-implants for orthodontic anchorage can move the canine faster and control the anchorage molar better than the segmental arch.%目的 比较片段弓技术和微种植体支抗在拉尖牙向远中的临床应用效果.方法 60例牙列拥挤,双侧对称拔除第一前磨牙且需将尖牙拉向远中的患者,随机分为2组,试验组尖牙远移时应用微种植体作为支抗,对照组则使用片段弓技术远移尖牙,测量尖牙向远中移动的距离以及磨牙近中倾斜的程度.结果 试验组尖牙移动的速率为(1.428±0.072)mm/月,快于对照组(1.137±0.081)mm/月;试验组磨牙近中倾斜程度为(1.27±0.18)°,小于对照组(1.91±0.13)°.经统计学检验差异均有显著性(P<0.05).结论 使用微种植体支抗拉尖牙向远中在牙齿移动速率以及控制磨牙近中倾斜等方面优于片段弓技术.

  16. 利用CBCT分析上颌前牙区微种植体支抗植入的安全范围%Quantitative study of maxillary anterior bone depth for micro-implant anchorage placement using cone beam CT

    Institute of Scientific and Technical Information of China (English)

    夏文倩; 顾永佳; 高美琴

    2013-01-01

    Objective:To investigate the bone depth of maxillary anterior interdental area for orthodontic micro-implant an-chorage. Methods:Maxillary anterior alveolar bone of 30 adults was scanned and reconstructed by cone beam CT , the mesio-distal interdental distance and labial-palatal bone depth were measured at 4,6,8,10 and 12 mm from the alveolar crest be-tween upper anterior dental roots. Results: The mesio-distal distance between central incisors was the widest in all measure-ment levels, while the labial cortical bone thickness was the thinnest. At the 8 mm-level,the shortest mesio-distal distance was between the roots of central and lateral incisors. At or above the 8 mm-level , the labial-palatal bone depth was the thinnest between central incisors, but the thickest between central and lateral incisors. It was seen in only 6 cases that the root length exceeded 12 mm. Conclusion:This study provides suitable bone thickness and bone depth for micro-screws place-ment of maxillary anterior region.%目的:利用锥形束CT(cone beam computed tomography,CBCT)对上颌前牙区各根间的近远中及唇腭侧骨质厚度进行测量分析,为确定正畸治疗植入微种植支抗的安全范围提供参考。方法:对30例成人患者上颌前牙区行CBCT扫描及三维重建,测量距上颌牙槽嵴顶4、6、8、10、12 mm水平上颌中切牙、侧切牙、尖牙根间区近远中向、唇腭向的距离。结果:上中切牙牙根间至牙槽嵴顶4、6、8、10 mm近远中间距均最宽,在距牙槽嵴顶8 mm 水平,中切牙与侧切牙牙根间近远中向距离最窄;中切牙牙根间骨厚度在唇腭向距牙槽嵴顶8 mm及以上水平最薄,中切牙与侧切牙牙根间骨厚度最厚。30例中有6例前牙区各牙根长度均>12 mm,其根间近远中向距离距牙槽嵴顶12 mm水平均较宽。结论:通过对扫描后颌骨影像的分析,明确了前牙区各牙根间骨量,为确定植入微种植支抗的安全范围提供参考。

  17. 荆岳长江公路大桥索塔锚固钢锚梁结构体系分析%Analysis of Steel Anchor Beam Structural System of Anchorage in Pylon of Jingyue Changjiang River Highway Bridge

    Institute of Scientific and Technical Information of China (English)

    张家元; 丁望星; 朱世峰

    2015-01-01

    荆岳长江公路大桥主桥为主跨816 m的双塔不对称混合梁斜拉桥,在成桥状态下,索塔锚固采用两端固定的钢锚梁结构体系。为研究钢锚梁平衡斜拉索索力的作用,验证超静定结构体系钢锚梁的合理性,采用ANSYS软件建立索塔锚固区有限元模型,分析钢锚梁施工过程中2种不同的支承体系方案,并通过足尺模型试验研究钢锚梁对斜拉索索力的分配比例。结果表明:斜拉索初张时采用边跨固定、中跨滑动,斜拉索张拉后两端固定结构体系的钢锚梁承担了斜拉索索力水平分力的83.7%,钢锚梁与塔壁对索力水平分力的分配比例为8∶2,该体系能够发挥钢锚梁平衡斜拉索索力的作用,且结构可靠度高。%The main bridge of Jingyue Changjiang River Highway Bridge is a asymmetric span hybrid girder cable‐stayed bridge with double pylons and with a main span of 816 m .The anchor‐age in a pylon of the bridge in completion state is of the steel anchor beam structural system with its two ends being fixed .To study the function of the anchor beam balancing the stay cable forces and to verify the rationality of the anchor beam of the statically indeterminate structural system , the software ANSYS was used to set up the finite element model for the anchorage in the pylon , 2 different support schemes adopted for construction of the anchor beam were analyzed and the ra‐tios of the stay cable forces distributed by the anchor beam were studied by means of the full‐scale model tests .The results of the study show that the anchor beam using the structural system with its side span end being fixed ,its central span end being slide at the time of initial tensioning of the stay cables and with its two ends being fixed after tensioning of the stay cables can bear 83 .7%horizontal component of the stay cable forces and the ratio of the horizontal component distributed by the anchor beam and pylon wall

  18. Nance弓和横腭杆在拉尖牙远移中支抗效果的研究%A clinical trail of the anchorage by Nance arch and transpalatal arch in the labioversion canine distal move

    Institute of Scientific and Technical Information of China (English)

    边翔; 杨永进; 法永红; 沈焕; 李志韧

    2012-01-01

    Objective: To evaluate the anchorage effects of Nance arch and transpalatal arch(TPA) in the labioversion canines dish move. Methods; Forty patients were recruited and randomly allocated into TPA group and Nance arch group. Enrollment criteria ir eluded Class I or Class II devision 1 maloclussion, moderate crowding and extraction of upper and lower first premolars. The caninj distal- movement therapy was completed in all the patients. Lateral cephalograms and study casts were collected before treatment and ; the clinical end point. Statistical analysis was performed using software package SPSS 17.0. Results: There was no significant diflei ence between the TPA and Nance arch groups in terms of prevention of mesial drift,stable width, vertical displacement and distal tip ping (P>0.05). However, the molar rotation was 8.50??.59?in TPA group and 3.70??1.20?in Nance arch group(P<0.05) Conclusion: Nance arch is more effective in prevention of mesio-palatal rotation in the canine-distal-movement therapy.%目的:研究Nance弓和横腭杆在拉尖牙远移过程中,二者在三维方向上磨牙支抗效果的比较.方法:选择Angle Ⅰ类中度拥挤,或Angle Ⅱ类Ⅰ分类软组织侧貌前突不明显者40人,随机分组,上、下颌减数双侧第一前磨牙,设计方案为中度支抗,两步法关闭拔牙间隙.排齐整平后和治疗阶段结束时取模型,拍摄口内像和头颅侧位片.测量各标志点的线距和磨牙角度变化.应用SPSS 17.0统计软件对测量结果行统计学分析.结果:2组在阻止上颌第一恒磨牙近中前移、水平宽度或垂直方向、近中倾斜差异无显著性,但在磨牙旋转的控制上,Nance弓组磨牙向近中舌向旋转3.70°±1.20°,横腭杆组向近中舌向旋转8.50°±3.59°(p<0.05).结论:在磨牙旋转支抗控制上,Nance弓明显优于横腭杆.

  19. Clinical study of traction preservation of maxillary anterior teeth residual root with microscrew anchorage%种植钉牵引保存上颌前牙残根的临床研究

    Institute of Scientific and Technical Information of China (English)

    温兴涛; 任柏林; 包丽娜; 李东健

    2015-01-01

    目的:通过种植钉辅助正畸加力牵引上前牙龈下残根,评价其使用效果。方法选择上前牙冠折病例18例,前牙10例,前磨牙8例。在需要牵引的牙齿附近植入2颗彼此平行的微种植钉,用树脂粘接托槽,将片段弓固定在托槽上,牵引龈下残根。结果所有患牙断端均达到龈缘上1mm以上,向移动距离为2.8~4.3mm。15例合格,3例修复体松动达Ⅱ度,判定为不合格。结论利用正畸方法牵引龈下牙根,再行桩冠修复,可有效地解决前牙美观的问题,这种方法不需要以邻牙或对牙作为支抗,能有效避免支抗牙移位或支抗丧失的不良反应。%Objective   To evaluate the effect of orthodontic extrusion with microscrew anchorage in the repair of reexposed subgingival residual root. Methods   A total of 18 cases of anterior teeth with crown fracture, 10 cases of anterior teeth, and 8 cases of premolar were chosen. Two parallel microimplants were implanted near the traction dental implant, with resin-bonded brackets. Segmental arch is fixed on the bracket and traction of subgingival residual root. Results   The broken end of all teeth reached a gingival margin of 1 mm. The distance of the occlusion to the mobile was 2.8 mm to 4.3 mm. Among 18 patients, 15 cases were qualified, and 3 cases of prosthesis were unqualified. Conclusion  Orthodontic traction with microscrew anchorage has good effect on the repair of under-the-gum residual root. The greatest advantage of this method is that it does not need to use adjacent teeth or antagonistic teeth as anchorage, thus effectively avoiding the

  20. 异型钢箱混凝土索塔锚固区空间力学行为研究%Spatial Mechanical Behavior Research of Cable-pylon Anchorage Zone of Steel Box Concrete Tower

    Institute of Scientific and Technical Information of China (English)

    党栋; 贺拴海; 赵煜; 李世安

    2012-01-01

    In order to grasp the force performance and stress distribution of shaped pylon steel anchor box under the action of the cable tension, with a main span of 555 m length of three towers cable-stayed and self-anchored suspension combined system bridge as the engineering background, through the ANSYS APDL command stream parametric programming, the different finite element models of pylon steel anchor box is established by the spatial solid element and shell element, the mechanical properties of cable-pylon anchorage zone were studied under the most unfavorable load combination, considering the stress state and distribution characteristics of steel anchor box under different orthodontic force. The results showed that;under the most unfavorable combination of loads, the stress was concentrated at the position of the anchor plate and pressure plate using the initial strain mode; the calculation results of solid element and shell element were consistent by uniform loading mode, which could reflect the real stress state of steel anchor box, but the shell element corner contact area prone to stress calculation distortion. The results provide the basis for the design and have some design reference value for the design of the same type bridge.%为了掌握异型索塔钢锚箱在索力作用下的受力性能和应力分布,以某主跨555 m 长的三塔斜拉-自锚式悬索组合体系桥为工程背景,通过 ANSYS 中 APDL 命令流参数化编程,分别采用空间实体单元与壳单元建立了不同的索塔钢锚箱有限元模型,对索塔锚固区在最不利荷载组合作用下的受力性能进行了研究,并考虑了在不同加力方式下钢锚箱应力状态和分布特点.结果表明:在最不利荷载组合作用下,采用初应变加力方式,在锚垫板与承压板位置处应力较集中;采用均布力加载方式下,实体单元与壳单元计算结果较为吻合,能真实反映钢锚箱受力状态,但壳单元角点接触部位易出现应

  1. 武汉鹦鹉洲长江大桥北锚碇新型沉井基础设计%Design of New Type Caisson Foundation for North Anchorage of Yingwuzhou Changjiang River Bridge in Wuhan

    Institute of Scientific and Technical Information of China (English)

    李明华; 杨灿文

    2011-01-01

    The main bridge of Yingwuzhou Changjiang River Bridge in Wuhan is a three-tower and four-span suspension bridge. After comparison of different design proposals, it was determined that a new type caisson structure of circular cross section and with multiple round wells would be used for the north anchorage foundation of the bridge. In the big size well in the center of the caisson, the crisscross diaphragm was set and along the periphery within the caisson, a number of small size wells were uniformly set. The caisson is 43 m high and has totally 8 lifts, of which the first lift is a steel shell concrete caisson and the rest parts of the caisson from the second to the eighth lifts are all of reinforced concrete caissons. In the construction of the caisson, the caisson was sunk down by no dewatering and the air curtain was provided in the caisson wall to reduce sinking difficulty and construction risk. The software FLAC3D was used to conduct numerical simulation and analysis of the construction process of the sinking and to evaluate the construction safety, the environmental effect caused by the construction and the deformation of the foundation to be applied with load after the bridge was put into operation. The results of the a-nalysis show that in the process of sinking the caisson in lifts, the caisson structure and ground deformation can meet the relevant requirements in the codes and the adverse influence of the construction on the ambient buildings and the river dyke can be effectively avoided.%武汉鹦鹉洲长江大桥主桥为三塔四跨悬索桥.该桥北锚碇基础经多方案比选采用多圆孔环形截面新型沉井结构.沉井中间大圆孔内设置十字形隔墙,圆环内沿圆周均布有小直径井孔.沉井总高43 m,共分8节,第1节为钢壳混凝土沉井,第2~8节均为钢筋混凝土沉井.北锚碇施工中采用不排水下沉、井壁增加空气幕等措施减小施工难度及风险.采用软件FLAC3D对沉井施工过程进

  2. 探讨杂交手术治疗锚定区不足的B型主动脉夹层的效果%To Explore the Effect of B Type Aortic Dissection in the Treatment of the Deifciency of Anchorage Zone in the Hybrid Operation

    Institute of Scientific and Technical Information of China (English)

    严哲

    2016-01-01

    目的:探讨杂交手术治疗锚定区不足的B型主动脉夹层的效果。方法选取我院2013年1月~2014年6月确诊为B型主动脉夹层的患者35例,纳入患者均不适合单独实施单纯覆膜支架植入术。根据患者的具体情况对患者实施杂交手术,对治疗效果进行分析。结果经本次调查结果可知,35例患者均顺利完成手术治疗,且无严重并发症。对患者进行为期20个月的随访,提示患者均生存,随访结果表明提示吻合口通畅,患者恢复状态理想,无不良反应事件发生。结论杂交手术治疗锚定区不足的B型主动脉夹层效果显著,安全性较高。%Objective To study the effect of B type aortic dissection in the treatment of the deifciency of anchorage zone in the anchorage zone. Methods 35 cases of patients with type B aortic dissection were diagnosed in our hospital from January 2013 to June 2014, and the patients were not suitable for implantation alone. According to the patient's specific conditions for the implementation of hybrid surgery, the treatment effect is analyzed.Results The results of this survey showed that 35 patients were successfully completed surgery, and no serious complications. Patients were followed up for a period of 20 months. The patients were all survival. The follow-up results showed that the anastomosis was unobstructed, the patients recovered, and no adverse events occurred.Conclusion The effect of B type aortic dissection in the treatment of anchorage zone is obvious, and the safety is high.

  3. 连续开大垂直曲强化上颌重度拥挤牙列矢状向支抗的临床研究%Effects of continuous open vertical loops on reinforcing sagittal anchorage in severe crowding dentition

    Institute of Scientific and Technical Information of China (English)

    黄红亮; 艾虹; 卢红飞; 唐敏

    2012-01-01

    Objective To evaluate the effects of continuous open vertical loops on reinforcing sagittal anchorage in the stage of alignment for severe crowding dentition. Methods Twenty patients with maxillary severe crowding were divided into two groups, underwent continuous open vertical loops and headgear anchorage combined with Nance arch to reinforce molar anchorage in the stage of alignment. Cephalometric analysis was performed to evaluate the movement of maxillary first molars before and after alignmentation. Results U6M-RL increased (1.34 ± 0.30) mm (t = 1. 41, P = 0.07) and (1.19±0.20) mm (t = 1.36, P=0.09), U6M-AP0 reduced (0.22±0.03) mm (t=0.91, P = 0.15) and (0.18 ± 0.02) mm (t=0. 88, P = 0. 19) in two groups respectively. There was no significant differences between two groups (P>0.05). Conclusion Continuous open vertical loops can reinforce sagittal anchorage as aligning teeth with severe crowding.%目的 探讨连续开大垂直曲在上颌重度拥挤牙列强化矢状向支抗的临床应用.方法 选择上颌重度拥挤、减数第一前磨牙的病例20例,随机分为试验组和对照组,每组10例.试验组采用直径0.36 mm(0.014英寸)澳丝弯制连续开大垂直曲,对照组采用上颌Nance弓配合口外弓,研究过程均为初步排齐上颌拥挤牙列,并使上颌尖牙远中移动至紧邻第二前磨牙近中,测量研究过程前后的上颌牙列矢状向支抗稳定性.结果 试验组U6M-RL增加(1.34±0.30) mm(t=1.41,P=0.07),对照组U6M-RL增加(1.19±0.20)mm(t=1.36,P=0.09),两组差异无统计学意义(t=1.82,P=0.08).试验组U6M-APo减少(0.22±0.03) mm(t =0.91,P=0.15),对照组U6M-APo减少(0.18±0.02) mm(t =0.88,P=0.19),两组差异无统计学意义(t=1.53,P=0.11).结论 连续开大垂直曲远中移动尖牙,初步排齐上颌牙列,较好地强化了上牙列矢状向支抗.

  4. 78 FR 67300 - Anchorage Regulations: Pacific Ocean at San Nicolas Island, Calif.; Restricted Anchorage Areas

    Science.gov (United States)

    2013-11-12

    ..., go to http://www.regulations.gov , type the docket number USCG-2012-0967 in the ``SEARCH'' box and...'' box and click ``SEARCH.'' Click on Open Docket Folder on the line associated with this rulemaking. You... Beach and the explosives safety arc around the Barge Pier at Daytona Beach (see figure 2 located in...

  5. 77 FR 50914 - Anchorage; Change to Cottonwood Island Anchorage, Columbia River, Oregon and Washington

    Science.gov (United States)

    2012-08-23

    ... City's concerns over noise, vessel exhaust, and visual impact in emergency anchoring situations will be... Environmental Health Risks and Safety Risks. This rule is not an economically significant rule and does not create an environmental risk to health or risk to safety that may disproportionately affect children....

  6. CLINICAL APPLICATION OF MICRO -SCREW IMPLANT ANCHORAGE IN TREATMENT OF ANGLE'S CLASS II DIVISION 1 MALOCCLUSION WITH DEEP OVERBURDEN JAWS%微螺钉种植体支抗在 Angle 氏 II 类1分类深覆颌深覆盖牙颌畸形治疗中的临床应用

    Institute of Scientific and Technical Information of China (English)

    张金望

    2015-01-01

    目的:应用微螺钉种植体支抗植入Angle氏II类1分类深覆颌深覆盖牙颌畸形患者上颌牙列,加强支抗,比较其上颌切牙与第一磨牙的位置变化,探讨自攻型微螺钉种植支抗比传统支抗是否具有优越性。方法选择Angle氏II类1分类深覆颌深覆盖患者68例,随机分为研究组和对照组。研究组使用自攻型微型种植钉作为支抗体;对照组使用Nance弓、横腭杆或口外弓联合作为强支抗。比较两组总的治疗时间,及治疗前后X线头影测量的线距和U1/SN的角度差值。结果①微型种植钉保持稳定而无松动,种植体周围软组织健康,无肿胀感染,患者无明显不适。②研究组平均疗程20个月,对照组平均疗程26个月。③研究组患者在软组织侧貌得到显著的改善,上下唇相对于审美平面分别内收4.26 mm和4.54 mm。 U1/SN角减小了10.2°;对照组上下唇相对审美平面分别内收2.88 mm和3.01 mm。两组之间的差异有统计学意义。研究组上颌第一磨牙矫治前后在前后向和垂直向未发生显著性移动( p>0.05),切牙在前后向发生显著性移动,组间的差异有统计学意义( p<0.01)。结论相比传统支抗技术,微螺钉种植支抗能够更好地控制牙齿移动,缩短整个治疗时间。%Objective To assess theapplication values of self -tapping micro-screw implant anchorage in treatment of Angle's class II division 1 malocclusion with deep overburden jaws , compared with the traditional anchor-age.Micro-screw implantswere inserted in maxillary teeth of patients with Angle's class II division 1 malocclusion with deep overburden jaws tostrengthen anchorage .Changesin position of the maxillary incisor and the first molar were compared.Methods 68 cases of Angle's class II division 1 malocclusion with deep overburden jaws were selected and randomly divided into the research group and the control group .The

  7. Core binding factor alpha 1 expression in condylar cartilage under different microscrew anchorage orthodontic forces%微支抗种植体及不同矫治力作用下髁突软骨中核心结合因子a1的表达

    Institute of Scientific and Technical Information of China (English)

    赵刚; 邵鑫; 李德超; 张庆宇; 王丹

    2011-01-01

    BACKGROUND: Recently, microscrew anchorage implant has been widely used in the orthodontics due to its simple operation, little trauma and strong anchorage, but it is rarely used in type Ⅱ intermaxillary extraction. OBJECTIVE: To establish the animal experiment model of orthodontic microimplant, to investigate the effects of orthodontic forces on the expression of core binding factor a1 (Cbfa1) in condylar cartilage and on condylar process modification. METHODS: Thirty 8-week-old healthy New Zealand rabbits were randomly divided into experimental group (n=24) and control group (n=6). According to different forces, the experimental group was randomly subdivided into four groups: 100 g, 200 g, 300 g, and 400 g. Rabbits from the experimental group were performed type Ⅱ intermaxillary extraction taking microscrew implants as anchorages. At 4 weeks after surgery, Cbfa1 expression in the condylar cartilage was detected. RESULTS AND CONCLUSION: Different orthodontic forces resulted in different Cbfa1 expression in the condylar cartilage. When orthodontic force was 100 g and 200 g, Cbfa1 expression was significantly higher compared with the control group and orthodontic force of 200 g lead to highest Cbfa1 expression. When the orthodontic force was 300 g, there was no significant difference between the experimental and control groups (P > 0.05). When orthodontic force was 400 g, Cbfa1 expression was significantly greater in the experimental group than in the control group (P < 0.05). Orthodontic force can influence the expression of Cbfa1 in the condylar cartilage, suggesting that appropriate orthodontic forces have good effects on remodeling condylar cartilage.%背景:近年来微支抗种植体以其操作简单、创伤小、支抗强等优点被正畸医生广泛应用于口腔正畸临床,但鲜见用于Ⅱ类颌间的牵引.目的:以微种植体为支抗,探讨不同矫治力促兔下颌前导后髁突软骨中核心结合因子a1 蛋白的表达及

  8. Clinical evaluation of simultaneously restoration for the missing posterior teeth by dental implants after suppressing the opposite elongated teeth with micro-implant anchorage%种植支抗压低对(牙合)伸长牙同期种植修复缺失后牙的临床研究

    Institute of Scientific and Technical Information of China (English)

    吴王喜; 陈筑苏; 孟波; 张君孝; 汤慧怡

    2012-01-01

    目的 研究种植支抗压低对(牙合)伸长牙同期种植修复缺失后牙的临床效果.方法 8例后牙缺失伴对(牙合)牙伸长的成年患者,利用支抗种植钉作为骨支抗,对16颗对(牙合)伸长牙进行正畸压低矫治,矫治结束前8~12周植入种植体,矫治结束时即刻进行上部结构修复.随访1年,观察临床效果.结果 8例患者16颗伸长对(牙合)牙压低矫治成功,平均压低疗程为7个月,缺失牙种植义齿修复后咀嚼功能正常;1年后随访,压低后的天然牙与种植义齿咬合稳定,X线片显示矫治压低的对(牙合)牙和种植义齿均未出现明显的骨吸收.结论 种植支抗压低对(牙合)伸长牙同期种植修复缺失后牙,缩短了疗程,有利于早期建立稳定的咬合关系,是一种可行的临床治疗选择.%Objective To study the effects of simultaneously restoration for the missing posterior teeth by dental im-plants after suppressing the opposite elongated teeth with micro-implant anchorage. Methods Eight Adult partial edentulous patients needing restoration with elongated opposite teeth were included in this study. 16 teeth were suppressed by micro-implant anchorage, 8 to 12 weeks to insert the dental implants before the end of orthodontics, implants restoration at the time of the end of suppressing, follow-up of 1 year. Results 8 cases had been suppressed successfully after treatment , with the average suppressing treatment of 7 months. The missing teeth were replaced by the regular prosthetic and re-gained the normal mastication function. Within the 1 year revisit period, the occlusion relationship between the orthodontic teeth and the prosthetic was stability and the bone level around the implants and the orthodontic teeth were stable under the X-ray. Conclusion Simultaneously restoration after suppressing elongated teeth by micro-implant anchorage could shorten the course of treatment, and keep the re-buiding occlusion stability, so it is suitable

  9. 利用颧牙槽嵴区种植钉矫正边缘性Ⅱ类错(牙合)%A clinical study on effects of distalization of whole upper arch in borderline Class H malocclusion using microscrew anchorages in inferiozygomatic area

    Institute of Scientific and Technical Information of China (English)

    张鸿军; 嵇国平; 沈刚

    2013-01-01

    PURPOSE:To investigate the effect of distalization of upper dentition using microscrew anchorages placed in inferiozygomatic area to correct borderline Class Ⅱ malocclusion.METHODS:Nine borderline Class Ⅱ cases aged from 13-17 years old,with moderate convex profile were selected.All cases were designed to extract upper second molars or third molar germs to provide space for distalization of upper dentition using microscrew anchorages placed in inferiozygomatic area.Cephalometrics before and after treatment were compared to analyze the movement of upper morlars and incisors,as well as the position change of upper and lower lips.The data were analyzed by paired t test with SPSS17.0 Software package.RESULTS:After an average of 14 months of treatment,all cases got improved profiles with correction of Class Ⅱ dental relationship.The upper molars and incisors were pulled back 3.1 mm and 2.8 mm,respectively.No adverse root resorption or sinus infection caused by the microscrews was observed.CONCLUSIONS:Microscrew anchorages placed in inferiozygomatic area can be used to correct borderline Class Ⅱ malocclusion by distalization movement of upper dentition with a better profile and no adverse complication.Supported by Medical Guide Project of Science and Technology Committee of Shanghai Municipality (09411964900).%目的:通过利用颧牙槽嵴区种植钉支抗整体远移上牙列而矫治边缘性Ⅱ类错(牙合),探索此类错(牙合)更简单、有效的矫治方法.方法:选择9例前牙前凸青少年(13~17岁)正畸患者,前牙Ⅰ~Ⅱ度深覆盖,磨牙为尖对尖远中关系,开唇露齿.正畸拔除上颌7或8牙胚,在颧牙槽嵴区植入自攻式微种植钉支抗,采用直丝弓矫治器,整平后直接在O.019×0.025英寸不锈钢方丝上用微种植钉支抗远中移动整个上牙列,并作治疗前、后X线头影测量分析,采用SPSS 17.0软件包中的配对t检验比较治疗前、后上、下唇位置,上、下颌第一磨牙及

  10. Clinic effect and corrective mechanics of nonextracted skeletal Class Ⅱ Malocclusion in multiloop edgewise arch wire technique with microimplant anchorage%微种植体支抗结合多曲方丝弓非拔牙矫治骨性Ⅱ类错(牙合)的临床研究

    Institute of Scientific and Technical Information of China (English)

    周嫣; 黄敏方; 方志欣; 陈世稳; 卢珍珍

    2013-01-01

    Objective Detected the corrective mechanics and clinic effects of nonextracted skeletal Class Ⅱ malocclusion in multiloop edgewise arch wire technique with microimplant anchorage. Methods 11 nonextracted skeletal Class II malocclusion patient whose dentition were media crowd and were treated by combinning technique of straighe wire.multiloop edgewise arch wire with microimplant anchorage were recruited.Paired -Sample T test of cephalometric variables before and after treatment were done in Spss 13.0. Results Skeletal Class Ⅱ facial type had been improved after treatment.ANB diminished 2.14°in average,labial or lingual inclination of upper anterior teeth had tend to normal.Upper molar moved distally 4.16mm.Overbite and Overjet of anterior teeth was in the standard range. Relation of first molar was neutral. Conclusion Multiloop edgewise arch wire technique with microimplant anchorage could obtain satisfied effect on the nonextracted correction of skeletal Class Ⅱ malocclusion,contribute to harmonious relation between bimaxilla, moving the whole upper dentition backward, limiting the exccessive labial and lingual inclination of upper anterior teeth, avoiding elongation of anterior crown for not using Class Ⅱ intermaxillary elastics during treatment, providing favourite occlusion of posterior teeth.This combining technique could improve the bimaxillary relation,lateral and positive facial appearance.intercuspid occlusion,guide a new and successful nonextracted correction on skeletal Class Ⅱ malocclusion patient who should be treated with extracted or nonextracted treatment to us.%目的:探索微种植体支抗结合多曲方丝弓非拔牙矫治骨性Ⅱ类错(牙合)的临床疗效.方法:微种植体支抗结合多曲方丝弓对11例骨性Ⅱ类伴中度牙列拥挤患者采用非拔牙方法矫治,SPSS13.0统计软件对矫治前后的头影测量变化值进行两样本配对t检验.结果:矫治后Ⅱ类骨面型得到了不同

  11. 两种直丝弓支抗形式矫治上颌前突的临床比较研究%Clinical study of two kinds of anchorage with straight-wire techniques in the treatment of maxillary protrusion patients

    Institute of Scientific and Technical Information of China (English)

    杨庆慧; 何欣; 刘松林

    2016-01-01

    Objective:To investigate the effect of sliding-transpalatal arch anchorage with MBT appliance and anchorage with Tip-Edge plus appliance in the treatment of maxillary protrusion.Methods:Thirty patients with maxillary protrusion, aged 11-17 years old, were selected and divided into sliding-transpalatal arch-MBT group and Tip-Edge plus group after extraction of four first premolars.All the patients were treated by MBT tech-nique and Tip-Edge plus technique, respectively.Lateral cephalometric radiographs before and after treatment were taken and analyzed.Results:The average forward movement of first upper molar did not change in two groups.The lower incisors were intruded 3.93°with reference to mandibular plane in MBT group,while in Tip-Edge plus group lower incisors were protruded 1.53°.The vertical height of bimaxillary first molars increased in sliding-transpalatal arch-MBT group.Plane of occlusion clockwise rotation in the Tip-Edge plus group.Conclu-sion:Maxillary protrusion patients could be treated successfully with straight wire and Tip-Edge Plus technique.Sliding-transpalatal arch anchorage system is effective in the plane of occlusion control and backward movement of incisor.Lower incisors were intruded more in the Tip-Edge Plus group than in the straight-wire group.%目的:比较滑动杆与横腭杆联合MBT直丝弓技术和Tip-Edge plus差动直丝弓技术治疗上颌前突的临床疗效。方法:选取11~17岁上颌前突病例30例,均拔除4颗第一前磨牙。 MBT直丝弓组15例( S+MBT组),使用直丝弓技术结合滑动杆与横腭杆强支抗治疗;Tip-Edge plus组15例( TP组),使用Tip-Edge差动直丝弓技术治疗。均在矫治前后行X线头影测量分析。结果:两组患者上颌支抗磨牙前移量治疗前后无显著性变化;S+MBT组L1-MP减小3.93°、L1-NB减小5.07 mm,差异有统计学意义;TP组L1-MP增加1.53°、L1-NB增加0.43 mm,差异无统计学意义。 TP组牙合平面顺

  12. 不同角度摇椅弓联合种植体支抗内收上牙列的三维有限元分析%Finite element analysis of maxillary dentition retracted with implant anchorage with different curves of archwires

    Institute of Scientific and Technical Information of China (English)

    刘海波; 冯雪; 吴晓雪; 牛茜楠

    2012-01-01

    目的 探讨不同角度摇椅弓在种植体支抗内收上牙列过程中的生物力学效应和影响,以期为临床应用种植体支抗内收上牙列时选择合适的摇椅弓角度提供参考.方法 建立种植体支抗内收上牙列的三维有限元模型,分析摇椅弓角度为5°、10°、15°时上牙列各牙的移动趋势.结果 当摇椅弓角度从5°增大至15°时,对前牙施加的唇向转矩力逐渐增加,对后牙施加的颊向转矩力逐渐增加,前牙的压低效果和后牙的升高效果逐渐明显.结论 通过改变摇椅弓角度可较好地控制各牙转矩以及明显改善深覆(牙合).种植体支抗内收上牙列时应根据前后牙情况选择适度的摇椅弓.%Objective To investigate the biomechanical effects of micro-implant anchorage for en-masse retraction of the maxillary dentition with different curves of archwires.Methods The mobile trends were calculated when the curve of archwires were 5°,10°,15° on the basis of 3D finite element model.Results With the curve of archwire increasing from 5° to 15°,the torque in anterior teeth and posterior teeth increased gradually,and the intruding effect of anterior teeth and the extruding effect of posterior teeth increased gradually.Conclusions The torque of teeth could be changed effectively with different curve of archwires.The reverse-curve arch wire was suitable for correcting deep overbite caused by over developed anterior alveolar bone.According to the position of posterior teeth,the appropriate curve of archwires should be selected when the implant anchorage was used to retract the whole dentition.

  13. 微型种植体支抗压低犬切牙移动过程中牙周牙根骨性组织的变化%Histological changes of tooth root and periodontal tissue during mini-implant anchorage for incisor intrusion in dogs

    Institute of Scientific and Technical Information of China (English)

    葛振林; 卢嘉静; 祁涛; 田佳灵; 杨彩霞

    2011-01-01

    BACKGROUND: Tooth intrusion easily leads to root resorption. Previous studies regarding orthodontic treatment-caused tooth root resorption or retrospective clinical studies based on X-ray films have great errors in outcome evaluation because of intrusion force which cannot be precisely controlled. OBJECTIVE: This study established dog models of mini-implant anchorage for incisor intrusion to observe the histological changes of tooth root and periodontal tissue and to evaluate the feasibility and safety of mini-implant anchorage for incisor intrusion. METHODS: Nine dogs were assigned to one control group (n = 1) and four experimental groups per time to sacrifice (1, 2, 4 and 12 weeks; n = 2 dogs for each experimental group). No force was added to the control group. In the experimental groups, mini-implant as an anchorage was placed in the buccal alveoli between maxillary second and third incisors on each side. A traction force of 100 g was imposed to each side to intrude the maxillary first and second incisors on each side. At 1, 2, 3, and 4 weeks (traction force was imposed for 4 weeks and after withdrawal of extraction force, mini-implant was retained in place for 8 weeks), dogs were sacrificed. The first and second incisors together with gingival and alveolar bone were completely resected to prepare histological specimens. Following hematoxylin-eosin staining, histological changes of tooth root and periodontal tissue were observed. RESULTS AND CONCLUSION: Compared with the control group, in the 1-week group, histological changes were primarily at the root tip and alveolar ridge crest, alveolar bone and cementum were absorbed and peridental membrane presented glassy degeneration in local region; in the 2-week group, bone resorption degree and range were obviously enlarged, and bone resorption developed from root tip, root middle part to cervical part; in the 4-week group, bone resorption was still active and the glassy degeneration of peridental membrane

  14. 种植体支抗结合片段弓矫治成人下颌牙列拥挤的临床应用研究%Correcting crowding of mandibular teeth by implant anchorage and partial arch wire for adult

    Institute of Scientific and Technical Information of China (English)

    郭军; 杨永进; 蔡兴伟; 李广; 黄长城

    2012-01-01

    Objective To evaluate clinical effects and the characters by micro-implant anchorage and partial arch ware correcting crowding of mandibular teeth in Class I malocclusal patients. Methods 24 Micro-implants were embedded buccal bone of mandibular first molar and mandibular second premolar of 12 Angle I malocclusal patients Ni-Ti coil spring was connected to implant and hook of distalization of mandibular lateral incisor so as to close space by contracting mandibular preteeth.Measuring buccolingual position changes of mandibular central incisors.compaction, angle of mesiodistal inclination.and moving velocity.root obsorbsion and periodontal membrane change.Evaluating anchorage by the change of mandibular first molar. Results Mandibular central incisorlingual movement and lingual inclination was 1.6mm,4.5 degree.compaction was 0.5mm,no mesiodistal inclination.course of treatment was 3.2 months, velocity of mandibular central incisor.No root obsorbsion and periodontal membrane change.Location of mandibular first molar was no changetable. Conclusion The problem of teeth crowding was resolved successfully.location of mandibualr molar and occlusion of posterion tooth was no changeable.%目的:研究安氏Ⅰ类错(牙合)患者中,采用种植体支抗结合片段弓技术,矫治成人下颌牙列 拥挤的临床效果及其作用特点.方法:选择12例成人患者,将24枚微型种植体植于下颌第一磨牙与下颌第二前磨牙之间的颊侧牙槽骨内,Ni-Ti螺旋 弹簧拉长后分别连接于种植体与下颌侧切牙远中的牵引钩,来内收下前牙关闭间隙.测量下颌中切牙的颊舌向的位置变化 、压低量、近远中倾斜度以及移动的速度,并通过治疗前后的X线片对比以观察切牙牙根有无吸收,牙周膜腔的变化情况.通过 测量下颌第一磨牙的位置变化来衡量支抗强弱.结果:下颌中切牙向舌侧移动1.6mm,舌侧倾斜4.5°,平均压低0.5mm,无近 远中倾斜,疗程3.2个

  15. A study of closed miniscrew anchorage in intrusion of mandibular incisors to correct deep overbite in adult patients%微螺钉支抗闭合式牵引压低下颌切牙矫治成人深覆(牙合)的临床研究

    Institute of Scientific and Technical Information of China (English)

    寻春雷; 黄一平; 赵弘

    2015-01-01

    Objective The purpose of this study is to investigate the effectiveness of the mandibular incisors intrusion by using closed miniscrew anchorage to correct the deep overbite in adult patients.Methods The sample comprised 20 adult patients with deep overbite who met the inclusion criteria.After surgical exposure of mandibular symphysis,one miniscrew was placed and closed up.Stainless steel ligature wire was tied with one end to miniscrew and the other end forming a cook exposed in oral cavity for later intrusion of mandibular incisors.Pre-and post-treatment cephalometric radiographs were measured and compared.Results All the patients had their deep overbite corrected,with an average decrease of 4 mm (P<0.001).The resistant center of mandibular incisors was intruded 2.8 mm remarkably (P<0.001).Meanwhile,significant labial proclination of the mandibular incisors were observed with increases in L1/MP and L1/NB (5.8° and 2.3°,respectively) and the decrease in Ul/L1 (P<0.01).With lower incisor intrusion and inclination,occlusal plane showed clockwise rotation,and the post-treatment MP/OP decreased significantly by 3.5° (P<0.001).The mandibular molars did not change significantly in inclination and vertical dimension.No significant root resorption of the incisors was found.Conclusions Intrusion of mandibular incisors through miniscrew anchorage could be used as an efficient method to correct deep overbite in adult patients.%目的 评价微螺钉支抗闭合式牵引压低下颌切牙矫治成人深覆(牙合)的有效性.方法 选择20例符合纳入标准的成人深覆(牙合)患者,在下颌中切牙间切开黏膜,于下颌骨正中联合部位植入微螺钉一枚,并以结扎丝连接穿出黏膜形成牵引钩,加力进行下前牙压低治疗.正畸治疗前后分别拍摄头颅侧位片,并进行头影测量的分析比较.结果 20例患者矫治后覆(牙合)均达正常范围,平均减小4.0 mm(P<0.001).下切牙抗力中

  16. 微种植钉支抗矫正对后牙锁牙合患者髁突形态及对称性的影响%Effects of micro-screw implant anchorage on condylar shape and symmetry in patients with posterior scissors-bite

    Institute of Scientific and Technical Information of China (English)

    张同凯; 华先明

    2015-01-01

    objective To explore the effects of micro-screw implant anchorage on condylar shape and symmetry in patients with posterior scissors-bite. Methods A total of 20 Class I unilateral posterior scissors-bite patients visiting our hospital from January 2013 to February 2014 were included in this study.All patients were given micro screw implant anchorage.CT imaging was used to observe the changes in condylar before and after treatment.Their normal right lateral teeth were used as controls. Results The condylar height,condylar surface area and condylar volume of 20 case patients with posterior scissors-bite were higher than that normal controls before treatments[(4.61 ± 1.09 Vs 3.52 ± 0.29)mm,(1201.32 ± 121.37 Vs 1010.23 ± 111.26)mm2,(1409.13 ± 168.24 Vs 1243.35 ± 147.08) mm3].The condylar height(3.60 ± 0.54)mm,condylar surface area(1009.15 ± 112.37)mm2 and condylar volume(1241.03 ± 137.18)mm3 were significantly lower after treatments.There was no statistically significant difference compared with normal group(P>0.05). Conclusion Early correction can effectively change the shape of the condyle and improve the degree of posterior occlusal and symmetry and is worthy of clinical use.%目的:探讨微种植钉支抗矫正对后牙锁牙合患者髁突形态及对称性的影响。方法:收取2014年1月-2015年1月到我院就诊的20例恒牙期安氏I类单侧后牙正锁牙合的患者,20例患者均采用微种植钉支抗矫正。采用颅颌面锥形束CT成像技术观察患者矫治前后髁突的变化,将各自正常对侧后牙作为对照,进行比对研究。结果:20例后牙锁牙合患者矫治前的髁突高度、髁突表面积及髁突体积都高于正常对照后牙[(4.61±1.09 Vs 3.52±0.29)mm、(1201.32±121.37 Vs 1010.23±111.26)mm2、(1409.13±168.24 Vs 1243.35±147.08)mm3];20例后牙锁牙合患者矫治后的髁突高度(3.60±0.54)mm、髁突表面积(1009.15±112.37)mm2、髁突体积(1241.03±137.18

  17. 应用锥形束CT探究上颌前牙区颌骨微种植支抗钉植入的安全区%Quantitative study of maxillary anterior bone depth and labial cortical bone thickness for micro- implant anchorage placement using cone beam CT

    Institute of Scientific and Technical Information of China (English)

    赵岩; 吴平

    2012-01-01

    目的:对上颌前牙区颌骨的骨量及唇侧骨皮质厚度进行测量分析,为正畸治疗植入微种植支抗钉的安全区提供参考.方法:对25例成人患者上颌前牙区行锥形束CT扫描及三维重建,测量距上颌牙槽嵴顶3、6、9、12mm水平上颌中切牙、侧切牙、尖牙根间区近远中向、唇腭向的距离以及唇侧骨皮质厚度.结果:在距上颌牙槽嵴顶3、6、9mm水平中切牙根间近远中向距离均最宽,唇侧骨皮质均最薄;在距牙槽嵴顶9mm水平中切牙与侧切牙根间近远中向距离最窄;在4个测量水平侧切牙与尖牙根间唇侧骨皮质均最厚;唇腭向在距牙槽嵴顶9mm及以上水平,中切牙根间骨厚度最薄,中切牙与侧切牙根间骨厚度最厚.25例中仅3例前牙区各牙根长度超过12mm,在距牙槽嵴顶12mm水平测出的根间近远中向距离均较宽.结论:通过对扫描后颌骨影像的分析,明确了前牙区颌骨的骨量及唇侧骨皮质厚度,为植入微种植支抗钉的安全区提供参考.%Objective: To investigate the bone depth and labial cortical bone thickness of maxillary anterior interdental area for orthodontic micro-implant anchorage. Methods; Maxillary anterior alveolar bone of 25 adults was scanned and reconstructed by cone beam CT, the mesio-distal interdental distance, labial-palatal bone depth and labial cortical bone thickness were measured at 3, 6, 9 and 12 mm from the alveolar crest between upper anterior dental roots. Results; The mesio-distal distance between central incisors was the widest in all measurement levels, while the labial cortical bone thickness was the thinnest. At the 9 mm-level, the shortest mesio-distal distance was between the roots of central and lateral incisors. The labial cortical bone thickness between lateral incisors and canines was the thickest in all measurement levels. At or above the 9 mm-level, the labial-palatal bone depth was the thinnest between central incisors, but the thickest

  18. 微种植体支抗结合多曲方丝弓矫治高角型骨性Ⅲ类错殆的临床研究%Treatment of Skeletal Class III Patients of High Angle with Microscrew Implant Anchorage and Multi-loop Edgewise Arch Wire.

    Institute of Scientific and Technical Information of China (English)

    马巧玲; 徐芸; 赵计林; 李煌

    2011-01-01

    目的:利用微种植体支抗和多曲方丝弓技术矫治高角型骨性Ⅲ类错(牙合)畸形,观察其临床疗效.方法:选取高角型骨性Ⅲ类错黯畸形患者16例,常规排齐整平后,采用微种植体支抗与多曲方丝弓技术相结合进行矫治.测量矫治前后的X线头颅侧位片并将测量结果进行配对t检验,评估疗效.结果:与矫治前相比,SNA角平均增加(2.48±0.65)°,L6-MP角平均减少(5.28±1.96)°,OP-MP平均增加(3.13±0.66)°,OJ平均增加(3.89±0.63)mm,OB平均增加(2.74±0.38)mm.结论:微种植支抗结合多曲方丝弓技术矫治轻、中度高角型骨性Ⅲ类错(牙合)畸形,在有效地控制磨牙垂直向高度同时矫正Ⅲ类错(牙合)颌间关系,达到了改善面型和掩饰骨性畸形的正畸治疗目标.%Objective: To evaluate the treatment effects of microscrew implant anchorage (MIA) and multi-loop edgewise arch wire (MEAW) therapy on skeletal class Ⅲ malocclusion of high angle. Methods: Sixteen skeletal class Ⅲ high-angle malocclusions were chosen (maleT, female 9). They were treated by MIA and MEAW tech-nique. Cephalometric analysis was performed with pre-treatment and post-treatment cephalograms. Paired ttest was conducted to assess the treatment effects. Results: After treatment, the increase of SNA, OP-MP, OJ and OB were (2.48±0.65)°, (3.13±0.66)°, (3.89±0. 63)mm and (2. 74±0.38) mm, respectively. L6-MP angle decreased by (5.28±1.96)°. Conclusion: Mild and moderate skeletal class Ⅲ of high angle can be treated successfully by MIA and MEAW technique.

  19. 微型种植体支抗辅助牵引成骨重建上颌骨部分缺损的效果评估%Mini-screw implant anchorage-assisted distraction osteogenesis for reconstruction of partial maxillary defect

    Institute of Scientific and Technical Information of China (English)

    冯贻苗; 沈国芳; 房兵; 毛丽霞; 娄新田

    2009-01-01

    PURPOSE:To evaluate the usefulness of self-made distraction osteogenesis instrument by orthodontic technique and mini-screw implant anchorage-assisted distraction osteogenesis(DO) to reconstruct partial maxillary defects. METHODS: Eight patients suffering from partial maxillary defects were selected. Their ages ranged from 19 to 43 years and the average age was 33.2 years. There were 5 males. After a special instrument was fabricated, elastic force trifocal distraction was performed by mini-implant borne aneborage. Three months later the implants were implanted in the two distracted region and the prosthetic restorations were finished finally. RESULTS: In the areas of distraction osteogenesis, ossifications were fine and alveolar bones were completed. The partial maxillary defects were repaired with the implant technique and the prosthodontie technique, and favourable occlusion was obtained. CONCLUSION: Combined orthodontic and DO techniques can reconstruct partial maxillary defect successfully and restore the complicated anatomical contour of the maxilla, especially the dental-alveolar bone.%目的:评价正畸技术自制牵引成骨装置及微型种植体支抗辅助弹力牵引重建上颌骨部分缺损的疗效.方法:选择5例上颌骨部分缺损病例,均为男性,年龄19~43岁,平均33.2岁.制作特殊的牵引装置.采用微型种植体支抗辅助支持的弹力牵引方式,进行三焦点式牵引成骨.3个月后,在两侧牵引区植入种植体,进行牙列修复.结果:骨缺损区牵引成骨后成骨良好,形成完整的牙槽嵴,可应用种植和托牙技术进行牙列修复,恢复良好的咬合关系.结论:对上颌骨部分骨缺损病例,可应用正畸技术和牵引成骨技术联合治疗,以恢复颌骨复杂的解剖结构,尤其是牙槽嵴,为牙列修复提供必备的条件.

  20. 微型钛钉种植体支抗压低犬上前牙过程中牙周组织骨保护素的表达%Osteoprotegerin expression changes in the periodontal tissue following titanium-alloy miniscrew as anchorage for the maxillary incisors intrusion

    Institute of Scientific and Technical Information of China (English)

    卢嘉静; 祁涛; 葛振林

    2011-01-01

    BACKGROUND: Osteoprotegerin (OPG) inhibits osteoclast (OC) formation and differentiation and increases bone density. It is akey factor for inhibiting bone resorption. However, the precise mechanism of OPG remains unclear following mini-implantanchorage for the maxillary incisors intrusion.OBJECTIVE: To observe the expression of OPG in the periodontal tissue following the mini-implant anchorage for the maxillaryincisors intrusion.METHODS: Nine dogs were selected and randomly divided into 5 groups: Ⅰ group was control group, including 1 dog with noforce given; Ⅱ, Ⅲ, Ⅳ, Ⅴ groups contained 2 dogs respectively. Mini-implants were inserted into the labial alveolar bonebetween the roots of maxillary the second and the third incisors on both sides; 100 g force was imposed on the first and thesecond incisors on both sides. At the end of 1, 2, 4, 12 weeks (activation for 4 weeks, then retention for 8 weeks after forceremoval), the animals were sacrificed, the first and second incisor teeth on the one side were randomly selected and these teethwith gums, alveolar bone tissue were completely cut. Then expression of OPG in periodontal ligament (PDL) was inspected byusing immunohistochemistry.RESULTS AND CONCLUSION: Expression of OPG in the alveolar bone and periodontal ligament tissues increased at 1 weekafter force given, reached maximum at 2 weeks after activation, and then dropped to normal level at 4 weeks after activation.After 12 weeks (activation for 4 weeks, then retention for 8 weeks after force removal), it increased insignificantly, which did notdiffer from that at 4 weeks after activation and the control group. OPG participated in the reconstruction of periodontal tissues anddynamically changed along with time following mini-implant anchorage for the maxillary incisors intrusion.%背景:在微型钛钉种植体支抗压低上前牙过程中,骨保护素可否发挥抑制骨吸收的作用,尚不十分清楚.目的:观察微型钛钉种植体支抗压低

  1. 76 FR 20524 - Anchorage Regulations; Port of New York

    Science.gov (United States)

    2011-04-13

    ..., design, or operation; test methods; sampling procedures; and related management systems practices) that... (over the Weehawken-Edgewater Federal Channel). The following graphics display the current boundary...

  2. Metabolism Kinetics of Glucose in Anchorage-dependent Cell Cultures

    Institute of Scientific and Technical Information of China (English)

    孙祥明; 张元兴

    2001-01-01

    The kinetic model of glucose metabolism was established and successfully applied to batchcultures of rCHO and rBHK cells. It was found that a large amount of glucose was utilized for cellmaintenance, and the overwhelming majority of maintenance energy from glucose was by its anaerobicmetabolism in both rBHK and rCHO cell cultures. The overall maintenance coefficients from aerobicmetabolism were 1.9×10-13 mmol/(cell.h) for rCHO cells and 7×10-13 mmol/(cell.h) for rBHK cells. Inaddition, all Go/T and Eo/T gradually increased with the same trend as the cell growth in the culture ofboth rCHO and rBHK cells. The overall molecule yield coefficients of lactate to glucose were 1.61 for rCHO cells and 1.38 for rBHK cells. The yield coefficients of cell to glucose were 4.5×108 cells/mmol for rCHO cells and 1.9 × 108 cells/mmol for rBHK cells, respectively.

  3. DCS Survey Submission for Municipality of Anchorage, AK PMR

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Survey data includes spatial datasets and data tables necessary to digitally represent data collected in the survey phase of the study. (Source: FEMA Guidelines and...

  4. 77 FR 45988 - Anchorage Regulations; Great Chebeague Island, ME

    Science.gov (United States)

    2012-08-02

    ... Chebeague Island, improve the safety of anchored vessels, and provide for the overall safe and efficient... INFORMATION section below for instructions on submitting comments. FOR FURTHER INFORMATION CONTACT: If you... of Homeland Security Management Directive 023-01 and Commandant Instruction M16475.lD, which...

  5. 78 FR 44917 - Anchorage Regulations; Port of New York

    Science.gov (United States)

    2013-07-25

    ... ground would be approximately 0.22 square nautical miles (2,010 yards long by 420 to 470 yards wide). The... area of approximately 0.07 square nautical miles (910 yards long by 300 yards wide). This proposed... coordinates to correspond to what is currently displayed on the navigation charts. Additionally, we would...

  6. Vector control in internal midface distraction using temporary anchorage devices.

    Science.gov (United States)

    Francis, Cameron; Rommer, Elizabeth; Mancho, Salim; Carey, Joseph; Hammoudeh, Jeffrey A; Urata, Mark M

    2012-11-01

    Le Fort III and monobloc distraction osteogenesis serve as the primary surgical treatment for children with severe midface hypoplasia. The orbital retrusion and class III malocclusion of patients with midface hypoplasia is best addressed with bodily advancement of the midface segment parallel to the cephalometric Frankfort horizontal plane. Use of internal distraction devices allows for advancement of the midface without extensive external hardware but comes at the cost of less vectorial control, resulting in a distraction vector that can cause a clockwise rotation of the entire midface or frontofacial component creating hollow appearing orbits. To counteract this clockwise rotation, we have developed a technique using orthodontic microimplants to anchor interarch class III relationship elastics. We report our experiences with this technique on a cadaveric model and as a case series of 17 patients who underwent midface distraction. A Le Fort III distraction procedure was carried out on a cadaver, and the orbital height was measured at 0-, 10-, and 20-mm distraction advancement with and without elastics in a class III relationship. Improvement of both subjective hollow appearance of the orbits and objective measurement of the orbital height with class III relationship elastics demonstrated the efficacy of class III relationship elastics in counteracting the clockwise rotation of the midface segment. A review of 17 patients with midface or frontofacial hypoplasia treated with Le Fort III or monobloc distraction with simultaneous microimplant anchored class III relationship elastics revealed correction of malocclusion and improved midface projection without significant increase in vertical height of the orbits.

  7. Geology. Grade 6. Anchorage School District Elementary Science Program.

    Science.gov (United States)

    Anchorage School District, AK.

    This resource book introduces sixth-grade children to the environment by studying rocks and other geological features. Nine lessons are provided on a variety of topics including: (1) geologic processes; (2) mountain building; (3) weathering; (4) geologic history and time; (5) plate tectonics; (6) rocks and minerals; (7) mineral properties; (8)…

  8. "Dinosaurs." Kindergarten. Anchorage School District Elementary Science Program.

    Science.gov (United States)

    Herminghaus, Trisha, Ed.

    This unit contains 15 lessons on dinosaurs for kindergarten children. It provides a materials list, supplementary materials list, use of process skill terminology, unit objectives, vocabulary, six major dinosaurs, and background information. Lessons are: (1) "Webbing"; (2) "Introduction to the Big Six"; (3) "Paleontology…

  9. "Dinosaurs." Kindergarten. Anchorage School District Elementary Science Program.

    Science.gov (United States)

    Herminghaus, Trisha, Ed.

    This unit contains 15 lessons on dinosaurs for kindergarten children. It provides a materials list, supplementary materials list, use of process skill terminology, unit objectives, vocabulary, six major dinosaurs, and background information. Lessons are: (1) "Webbing"; (2) "Introduction to the Big Six"; (3) "Paleontology and Fossils"; (4) "How Big…

  10. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, MUNICIPALITY OF ANCHORAGE, ALASKA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  11. Mini-implants for direct or indirect orthodontic anchorage

    NARCIS (Netherlands)

    Ren, Yijin

    2009-01-01

    DATA SOURCES: Studies were sourced using Medline, the Cochrane Library and hand searches of key orthodontic journals. STUDY SELECTION: The review was restricted to peer-review articles (randomised controlled studies, prospective clinical studies and retrospective clinical studies) dealing with mini-

  12. Rapid Degradation of Concrete Anchorage Performance by Liquid Water

    OpenAIRE

    2015-01-01

    Sludge ejection from the foundation of a wind turbine tower fixed by the anchor-ring method and the resulting sludge buildup have been confirmed to cause the undesirable phenomenon of lifting of the tower. Using specimen that is a pirtial model of the wind turbine foundation, this study investigates the influence of liquid water, differences in W/C, and differences in loading speed, to analyze developing factors on the concrete damage . The results shows that penetration of liquid water from ...

  13. 75 FR 76275 - Anchorage Regulations; Long Island Sound

    Science.gov (United States)

    2010-12-08

    ... anchored vessel that is conducting bunkering or lightering operations. Anchored vessels conducting bunkering or lightering operations are readily identified as they must display a red flag as required by 46... conducting bunkering or lightering operations. The revised provision is clearer, and preserves...

  14. 75 FR 22323 - Anchorage Regulations; Port of New York

    Science.gov (United States)

    2010-04-28

    ... grounds. The Coast Guard proposes to add a requirement that any vessel conducting lightering or bunkering... conducting lightering or bunkering operations shall display by day a red flag (Pub 102; International Code...

  15. 78 FR 11099 - Safety Zone Within the Lower Portion of Anchorage #9, Mantua Creek Anchorage; Paulsboro, NJ

    Science.gov (United States)

    2013-02-15

    ... opportunity to comment pursuant to authority under section 4(a) of the Administrative Procedure Act (APA) (5 U... authority citation for part 165 continues to read as follows: Authority: 33 U.S.C 1231; 46 U.S.C....

  16. 种植体支抗结合多曲方丝弓技术矫治成年Ⅱ类高角骨面型错(牙合)的临床研究%Treatment of skeletal Class Ⅱ adult patients with microscrew implant anchorage and multi-loop edgewise arch wire

    Institute of Scientific and Technical Information of China (English)

    周嫣; 黄敏方; 方志欣; 陈世稳; 欧晓丽

    2008-01-01

    Objective To evaluate the effects and mechanisms of the mieroscrew implant anchorage (MIA) combined with multi-loop edgewise arch wire (MEAW) technique in the treatment of skeletal Class Ⅱ. Adult patients. Methods Eleven adult patients with skeletal Class Ⅱ high-angle maloeelusions were treated with fixed appliances. The spaces were closed by the springs from the MIA to the hook on the arehwire. The height of the hook and the direction of the force were different according to the intrusion and retraction of upper anterior teeth. In the finishing stage, MEAW technique and modified class Ⅱ elastics (from the first loop of MEAW to the MIA) were used for final detailing. Cephalometric analysis was used to evaluate the effect after treatment. Results After treatment, the decrease of SNA, ANB and FMA were ( 2. 86 ± 1.05 )° , ( 2. 82±0. 96 )° and ( 2.95 ± 1.35 )° , respectively. The torque control of upper anterior teeth was good. The protrusion of lower incisors and the molar extrusion were avoided. The upper molars were moved distally by ( 3. 00 ± 2. 19) nun. Conclusions The treatment of adult patients with skeletal Class Ⅱ high angle maloeelusions with MIA and MEAW technique could not only improve the facial esthetics but also avoided the common side effects of traditional Class Ⅱ elastics .%目的 探讨种植体支抗结合多曲方丝弓技术矫治成年Ⅱ类高角骨面型错(牙合)的机制与疗效.方法 对11例成年Ⅱ类高角骨面型错(牙合)患者采用固定矫治技术配合种植体支抗关闭拔牙间隙,根据上前牙压低和内收方式的小同选用牵引钩的长度及牵引方向.矫治后期用多曲方丝弓技术调整(牙合)关系,并将传统Ⅱ类颌间牵引改良为颌内牵引.对矫治前后头影测量项目进行配对资料的t检验.结果 矫治后SNA角减少(2.86±1.05)°,ANB角减少(2.82±0.96)°,眼耳平面-下颌平面角(FMA角)减少(2.95±1.35)°.上前牙牙根得到较好的控制,未见上

  17. 基于锥形束 CT 的强支抗内收上前牙病例牙根及牙槽骨的形态学分析%Morphological analysis of roots and alveolar bone changes after upper anterior retraction with maximum anchorage based on cone-beam computed tomography

    Institute of Scientific and Technical Information of China (English)

    温馥嘉; 陈贵; 刘怡

    2016-01-01

    腭侧最为明显。%Objective:To investigate the remodeling of alveolar bone and the changes of roots after an-terior retraction with maximum anchorage by analyzing CBCT data from adult cases.Methods:The sam-ple comprised 48 incisors and 24 canines from 12 patients (18 to 40 years of age)with problems of ma-xillary protrusion or upper arch protrusion.CBCT scans were exposed before and after treatment,and la-teral cephalometric images as well as multiple planar reconstruction images were reconstructed.Tracing superimpositions of sagittal sections and three-dimensional reconstructions were done for qualitative analy-sis.For all maxillary anterior teeth,changes of root length,alveolar bone height and labial-palatal thick-nesses at different levels were evaluated.The average of measurements taken by the same tester in three times was processed by SPSS 17.0 statistical package.Results:In 6 of the 12 cases,alveolar thickness became thinner on labial side [apical area:(-0.64 ±1.18)mm]while thicker on palatal side [apical area:(0.93 ±2.0)mm]and the root length decreased[(-0.95 ±0.79)mm].In the other 6 cases, the incisors’alveolar bone became thicker on labial side [apical area:(2.12 ±1.46)mm]while thin-ner on palatal side [apical area:(-2.88 ±0.58)mm]and the loss of root length was obvious[(-2.12 ± 1.43)mm].In all the 12 cases,the canines’alveolar bone became thinner on labial side especially on the apical level [(-0.27 ±1.86)mm]while greatly thicker on palatal side [apical area:(6.40 ± 6.00)mm]and the root resorption was slight [(-1.12 ±1.19)mm].For all the anterior teeth,the height of alveolar bone reduced around them after retraction.Conclusion:When the root apical moved more palatally,more root resorption would occur and the alveolar bone would get thicker on labial side but thinner on palatal side and thinner as a whole after anterior retraction with maximum anchorage.In the vertical direction,the height of the alveolar bone generally decreased on all sides and decreased the most on the palatal

  18. Logistic regression analysis of risk factors associated with the stability of miniscrews used as orthodontic anchorage%口腔正畸患者微型种植体支抗钉稳定性危险因素的 Logistic 回归分析

    Institute of Scientific and Technical Information of China (English)

    戴兵; 杨柏霞; 王海艳

    2016-01-01

    Objective:To evaluate risk factors that affect the stability of miniscrew used asorthodontic anchorage.Methods:A total of eighty malocclusional patients from August 2012 to February 2015 in our hospital were enrolled (inclusion criteria:malocclu-sional patients without severe heart,brain and lung disease,without severe liver and kidney disfunction,without neural and mental dis-eases,without contraindications for surgery and tooth extraction)and divided into two groups based on whether the minicrews were loos-en,lost,shifted or not:stable group (57 patients with 241 miniscrews)and unstable group (23 patients with 28 miniscrews).Ten po-tential risk factors,including age,gender,length of minicrews,oral hygiene status,inflammation of the peri-implant tissue,sites and an-gle of loading,the time of initial load application,methods and duration of loading,were firstly screened using univariate analysis,and the significant risk factors were further determined by employing multiple logistic regression analysis.Results:5 significant risk factors were found by univariate analysis,which were age,the time of initial load application,the lasting time of loading,oral hygiene status and Inflammation of the peri-implant tissue.Further study with multiple logistic regression analysis indicated that age was positively associat-ed with the stability of minicrews,while the time of initial load application,lasting time of loading,oral hygiene status and Inflammation of the peri-implant tissue were negatively associated with the stability of minicrews.Conclusion:Age,the time of initial load applica-tion,lasting time of loading,oral hygiene status and Inflammation of the peri-implant tissue were risk factors associated with the stability of minicrews.This information will help to optimize the therapeutic strategies and improve the clinical efficacy.%目的:探讨影响微种植体支抗钉稳定性的危险因素。方法:对80例错牙合患者进行微型种植体支抗正畸治疗

  19. Teacher's Resource Book for Magnets. Grade 1. Revised. Anchorage School District Elementary Science Program.

    Science.gov (United States)

    Anchorage School District, AK.

    This resource book introduces first-grade children to the world of magnetism and magnetic effects. The students are provided the opportunity to observe interactions between magnets, identify what materials a magnet will and will not attract, study magnetic fields, induce temporary magnetism, make an electromagnet, and use compasses. The 16 lessons…

  20. 49 CFR 571.225 - Standard No. 225; Child restraint anchorage systems.

    Science.gov (United States)

    2010-10-01

    ... parallel to the vehicle's vertical longitudinal plane through the X point on the test device, and, (2...) Applied— (1) In a forward direction parallel to the vehicle's longitudinal vertical plane, and (2... parallel to the vehicle's longitudinal centerline; (2) Initially, along a horizontal line or along any...

  1. 49 CFR 571.210 - Standard No. 210; Seat belt assembly anchorages.

    Science.gov (United States)

    2010-10-01

    ... centerline of the vehicle for forward and rear facing seats, and in a plane perpendicular to the longitudinal... Figure 3, in a plane parallel to the longitudinal centerline of the vehicle for forward and rear facing seats, and in a plane perpendicular to the longitudinal centerline of the vehicle for side facing...

  2. 78 FR 11097 - Artificial Island Anchorage No. 2 Partial Closure, Delaware River; Salem, NJ

    Science.gov (United States)

    2013-02-15

    ... Administrative Procedure Act (APA) (5 U.S.C. 553(b)). This provision authorizes an agency to issue a rule without... follows: PART 165--REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS 0 1. The authority citation...

  3. 33 CFR 166.200 - Shipping safety fairways and anchorage areas, Gulf of Mexico.

    Science.gov (United States)

    2010-07-01

    ... Navigation or danger markings must be installed as required by 33 CFR Subchapter C. (c) Special Conditions...: For Federal Register citations affecting § 166.200, see the List of CFR Sections Affected,...

  4. F00267: NOS Hydrographic Survey , Chesapeake Bay Hurricane Anchorages, Virginia, 1984-06-21

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  5. Electric-field-enhanced nutrient consumption in dielectric biomaterials that contain anchorage-dependent cells.

    Science.gov (United States)

    Belfiore, Laurence A; Floren, Michael L; Belfiore, Carol J

    2012-02-01

    This research contribution addresses electric-field stimulation of intra-tissue mass transfer and cell proliferation in viscoelastic biomaterials. The unsteady state reaction-diffusion equation is solved according to the von Kármán-Pohlhausen integral method of boundary layer analysis when nutrient consumption and tissue regeneration occur in response to harmonic electric potential differences across a parallel-plate capacitor in a dielectric-sandwich configuration. The partial differential mass balance with diffusion and electro-kinetic consumption contains the Damköhler (Λ(2)) and Deborah (De) numbers. Zero-field and electric-field-sensitive Damköhler numbers affect nutrient boundary layer growth. Diagonal elements of the 2nd-rank diffusion tensor are enhanced in the presence of weak electric fields, in agreement with the formalism of equilibrium and nonequilibrium thermodynamics. Induced dipole polarization density within viscoelastic biomaterials is calculated via the real and imaginary components of the complex dielectric constant, according to the Debye equation, to quantify electro-kinetic stimulation. Rates of nutrient consumption under zero-field conditions are described by third-order kinetics that include local mass densities of nutrients, oxygen, and attached cells. Thinner nutrient boundary layers are stabilized at shorter dimensionless diffusion times when the zero-field intra-tissue Damköhler number increases above its initial-condition-sensitive critical value [i.e., {Λ(2)(zero-field)}(critical)≥53, see Eq. (23)], such that the biomaterial core is starved of essential ingredients required for successful proliferation. When tissue regeneration occurs above the critical electric-field-sensitive intra-tissue Damköhler number, the electro-kinetic contribution to nutrient consumption cannot be neglected. The critical electric-field-sensitive intra-tissue Damköhler number is proportional to the Deborah number.

  6. 78 FR 51061 - Special Anchorage Areas; Port of New York, NY

    Science.gov (United States)

    2013-08-20

    ... safety of anchored vessels, and provide for the overall safe and efficient flow of vessel traffic and... in length, increase the safety of life and property in New York City, improve the safety of anchored... Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide the Coast Guard...

  7. Facemask therapy with miniplate implant anchorage in a patient with maxillary hypoplasia

    Institute of Scientific and Technical Information of China (English)

    ZHOU Yan-heng; DING Peng; LIN Ye; QIU Li-xin

    2007-01-01

    @@ Areverse headgear is thought to be an effective treatment approach for skeletal class Ⅲ malocclusion with retruded maxilla. Clinical studies have shown that the changes of occlusion are a combination of skeletal and dental changes: forward movement of the maxilla, proclination of the maxillary incisors, clockwise rotation of the mandible, and retroclination of the mandibular incisors.1,2 However, the undesirable dental effects, such as excessive mesial movement and extrusion of maxillary molars and labial tipping of maxillary incisors, have been reported.

  8. Physical Model of Knik Arm and the Port of Anchorage, Alaska

    Science.gov (United States)

    2010-05-01

    to model dimensions and contoured on a plan view drawing in AutoCAD software. Template lines were selected based on the contours. When possible...be raised and lowered manually precise vertical distances for calibration. Water level gauges were calibrated daily with the water motionless and...modified based on aerial photography that was scaled and superimposed on the AutoCAD drawing of model contours. Up to this juncture in the testing, a

  9. Fatigue of threaded rods in cable anchorages due to Vortex shedding

    NARCIS (Netherlands)

    Maljaars, J.; Snijder, H.H.

    2013-01-01

    The 'Hovenring' is a bicycle roundabout flyover built as a signature bridge with a central steel pylon carrying a circular bridge deck suspended through stay-cables. Shortly after installation of the bridge, the stay-cables turned out to vibrate in the wind due to vortex shedding. These vibrations h

  10. 77 FR 60081 - Anchorages; Captain of the Port Puget Sound Zone, WA

    Science.gov (United States)

    2012-10-02

    ... to know that they reached the Facility, please enclose a stamped, self-addressed postcard or envelope... Positioning System (GPS), is much more practical and accurate for the mariner. Additionally, changes to...

  11. Clean Air for Anchorage and Fairbanks: Curriculum for Grades 1-6.

    Science.gov (United States)

    South East Regional Resource Center, Juneau, AK.

    Through the 10 lessons in this guide, elementary school students can be introduced to the characteristics of air, methods of air pollution control, air movement, and the health effects of polluted air. A directory of field trip sites and a list of teacher resources is included. Contained in each lesson plan are a materials list, general…

  12. Clean Air for Anchorage and Fairbanks: Curriculum for Grades 7-12.

    Science.gov (United States)

    South East Regional Resource Center, Juneau, AK.

    Ten lessons on air and air pollution comprise this guide for secondary school teachers. Among the topics addressed are pollutants, health effects, weather inversions, personal involvement, and automobile emissions. Particular emphasis is placed upon problems in Alaskan cities. Lesson plans contain a materials list, background information,…

  13. Influence of intentional ankylosis of deciduous canines to reinforce the anchorage for maxillary protraction

    Directory of Open Access Journals (Sweden)

    Luís Fernando Castaldi Tocci

    2013-02-01

    Full Text Available INTRODUCTION: This retrospective cephalometric study analyzed the influence of intentional ankylosis of deciduous canines in patients with Class III malocclusion and anterior crossbite, in the deciduous and early mixed dentition stages, treated by orthopedic maxillary expansion followed by maxillary protraction. METHODS: Lateral cephalograms of 40 patients were used, divided in 2 groups paired for age and gender. The Ankylosis Group was composed of 20 patients (10 boys and 10 girls treated with induced ankylosis and presenting initial and final mean ages of 7 years 4 months and 8 years 3 months, respectively, with a mean period of maxillary protraction of 11 months. The Control Group comprised 20 patients (10 boys and 10 girls treated without induced ankylosis, with initial and final mean ages of 7 years 8 months and 8 years 7 months, respectively, with a mean period of maxillary protraction of 11 months. Two-way analysis of variance and covariance analysis were applied to compare the initial and final cephalometric variables and the treatment changes between groups. RESULTS: According to the results, the variables evidencing the significant treatment changes between groups confirmed that the intentional ankylosis enhanced the sagittal response of the apical bases (Pg-NPerp and increased the facial convexity angles (NAP and ANB. CONCLUSIONS: The protocol involving intentional ankylosis of deciduous canines enhanced the sagittal response of the apical bases.INTRODUÇÃO: nesse estudo cefalométrico retrospectivo, analisou-se a influência da anquilose intencional de caninos decíduos em pacientes com má oclusão de Classe III e mordida cruzada anterior, nos estágios de dentição decídua e mista precoce, tratados com expansão ortopédica da maxila, seguida de tração reversa. MÉTODOS: foram utilizadas telerradiografias em norma lateral de 40 pacientes, divididos em 2 grupos pareados por idade e sexo. O Grupo Anquilose foi constituído de 20 pacientes (10 meninos e 10 meninas tratados com anquilose induzida e que apresentavam as idades médias inicial e final, respectivamente, de 7a 4m e 8a 3m, e o tempo médio de tração reversa de 11 meses. O Grupo Controle, composto de 20 pacientes (10 meninos e 10 meninas tratados sem anquilose induzida e que apresentavam as idades médias inicial de 7a 8m e final de 8a 7m, e tempo médio de tração reversa de 11 meses. Foram empregadas as análises de Variância a dois critérios e de Covariância para comparar as variáveis cefalométricas inicial e final e as alterações de tratamento entre os grupos. RESULTADOS: segundo os resultados, as variáveis que evidenciaram as mudanças de tratamento significativas entre os grupos confirmaram que o procedimento de anquilose intencional potencializou a resposta sagital das bases apicais (Pg-NPerp e aumentou os ângulos de convexidade facial (NAP e ANB. CONCLUSÃO: o protocolo envolvendo a anquilose intencional de caninos decíduos potencializou a resposta sagital das bases apicais.

  14. Bimaxillary protrusion with masseter muscle hypertrophy treated with titanium screw anchorage and masseter surgical reduction.

    Science.gov (United States)

    Hashimoto, Takashi; Kuroda, Shingo; Kamioka, Hiroshi; Mishima, Katsuaki; Sugahara, Toshio; Takano-Yamamoto, Teruko

    2009-04-01

    This case report describes the treatment of a patient with bimaxillary protrusion and masseter muscle hypertrophy. At age 21 years 7 months, this woman had temporomandibular disorder (TMD) symptoms, severe bimaxillary protrusion, and a prominent mandibular angle with facial asymmetry. After an attempt to alleviate the TMD symptoms with occlusal splint stabilization, portions of the masseter muscle and the mandible were surgically removed. Titanium screws were placed bilaterally in both arches, and a retraction force was applied. After active treatment for 38 months, the convexity of the facial profile with lip protrusion was improved remarkably, and good occlusion was achieved. The prominent mandibular angle with facial asymmetry was improved as a result of the surgical reduction of the masseter muscle and the modeling ostectomy near the masseteric tuberosity. The TMD symptoms disappeared, and the jaw movement pattern became normal. Therefore, our results suggest that this combination treatment would be useful for masseter muscle hypertrophy for morphologic and functional problems.

  15. 77 FR 19155 - Federal Motor Vehicle Safety Standards; Seat Belt Assembly Anchorages; Incorporation by Reference

    Science.gov (United States)

    2012-03-30

    ... Male Dummy,'' Volume 2, UMTRI, DOT HS 806 716. NHTSA developed the specifications for the FAD2, the... and the FAD2, and, for comparison purposes, the dimensions of the Hybrid III (HIII) test dummies... submitted to the docket electronically by logging into http://www.regulations.gov . Follow the...

  16. H08918: NOS Hydrographic Survey , Anchorage Area, West Side, Christmas Island, 1962-04-06

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  17. H10232: NOS Hydrographic Survey , Tampa Bay Anchorage Area, Florida, 1986-08-28

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  18. 77 FR 43514 - Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI

    Science.gov (United States)

    2012-07-25

    ... questions on this rule, call Mr. Edward G. LeBlanc at Coast Guard Sector Southeastern New England, 401-435... Area from the Code of Federal Regulations. Discussion of Comments and Changes We received nine comments on the proposed rule. One letter, from the Office of Environmental Policy and Compliance,...

  19. 75 FR 66686 - Federal Motor Vehicle Safety Standards; Seat Belt Assembly Anchorages, School Bus Passenger...

    Science.gov (United States)

    2010-10-29

    ... Standards (telephone: 202-366-0247) (fax: 202-366-4921), NVS-113. For legal issues, Ms. Dorothy Nakama... 305 mm (8.5 in x 12.2 in) rigid plate be used to ``simulate the shape of a single 6-year-old'' child, and that the agency should ballast the plate to ensure an evenly-distributed 22 kg (48.4 lb) mass....

  20. Ancient anchorage systems in India with reference to the Gujarat coast

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh; Tripati, S.

    . There are three main type of glazed ware i.e. green, blue and brown. These are very similar to the Islamic glazed ware found from various parts of the country (Mohammad, 1985, 105). The medieval period glazed ware at Hastinapur (Lal, 1954-55, 5-151) was found...-Arab type and they have been dated between the 10 th and the 14 th century AD on the basis of finding of the Islamic glazed ware along with the anchors. Similarly, anchors have been reported from Hathab and Gopnath. The most interesting anchor includes...

  1. Ancient technology of jetties and anchorage system along the Saurastra coast, India

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh

    to the Islamic glazed ware found in various parts of India (Mohammad 1985: 105). The medieval glazed ware from Hastinapur (Lal 1954–5: 5–151) was found with coins of Balban (AD 1206–87). The sherds recovered from Ghogha are similar to those reported from...

  2. Method for predicting selective uprooting by mechanical weeders from plant anchorage forces

    NARCIS (Netherlands)

    Kurstjens, D.A.G.; Kropff, M.J.; Perdok, U.D.

    2004-01-01

    Reliable mechanical weed control requires knowledge of the achievable levels of weed control and crop damage when using certain implements in specific conditions. Quantitative methods that use weed, crop, soil, and cultivator characteristics to predict weed control and crop damage need to be develop

  3. Denmark: criminal law as an anchorage point for pro-active anti-terrorism legislation

    DEFF Research Database (Denmark)

    Vestergaard, Jørn

    2012-01-01

    The article focuses on the compatibility of criminal law anti-terrorism legislation in Danish law with basic principles regarding the rule of law and due process. The so-called anti-terror-packages of 2002 and 2006 involve a set of rather uncertain and wide-reaching provisions fundamentally...... challenging the principle of legality and substantially widening of the scope of criminal law. These provisions criminalize various activities more or less remote from actual or attempted terrorist acts and participation in such activities, too. The legislature has even over-implemented vari-ous legal......, the challenges regarding rule of law and due process also relate to secondary legislation in fields like law enforcement, criminal procedure, intelligence, public law, treatment of foreigners, etc....

  4. Remedial Investigation/Feasibility Study, Operable Unit 5, Elmendorf AFB, Anchorage, Alaska. Volume 1. Text

    Science.gov (United States)

    1994-03-04

    x1IV 1.67 x101 31655 014 0 WAS. IAmmdo 2.6-6.4 4.64 x100 US x 10’ 11.4 014 0 Roo. abib 50.3-96.7 7.19 x1If 7.54 x1IV 214.3 014 0 Root cadmim i 1.5-l...0.51 0.70 No ɘ.0005 ɘ.0005 • Cadmim 1.3 0.68 - 1.1 2.53 No ɘ.0012 ɘ.0012 Calcium 6,S20 5,090 - 5,610 8,490 No 3.7727 7.1394 Chromium 25.5 9.8. 12.0...L.auumpewmae Cadmim 11.3-27.5 4.2-6.5 Caper72-195 13-41 __________ ________ _ Lead 290 8 psmm;Cdim2.3 1.1 Copper 750 41 _________ _________ Liad 420 31

  5. Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells

    Directory of Open Access Journals (Sweden)

    Xuesong Liu

    2001-01-01

    Full Text Available The serine/threonine kinases, Akti/PKBα, Akt2/PKBβ, and Akt3/PKBγ, play a critical role in preventing cancer cells from undergoing apoptosis. However, the function of individual Akt isoforms in the tumorigenicity of cancer cells is still not well defined. In the current study, we used an AM antisense oligonucleotide (AS to specifically downregulate Akti protein in both cancer and normal cells. Our data indicate that AM AS treatment inhibits the ability of MiaPaCa-2, H460, HCT-15, and HT1080 cells to grow in soft agar. The treatment also induces apoptosis in these cancer cells as demonstrated by FRCS analysis and a caspase activity assay. Conversely, Akti AS treatment has little effect on the cell growth and survival of normal human cells including normal human fibroblast (NHF, fibroblast from muscle (FBM, and mammary gland epithelial 184135 cells. In addition, AM AS specifically sensitizes cancer cells to typical chemotherapeutic agents. Thus, Akti is indispensable for maintaining the tumorigenicity of cancer cells. Inhibition of AM may provide a powerful sensitization agent for chemotherapy specifically in cancer cells.

  6. 77 FR 5743 - Special Anchorage Areas; Port of New York, NY

    Science.gov (United States)

    2012-02-06

    ... intended to increase the safety of life and property in New York City and Atlantic Highlands, NJ, improve... Street Boat Basin. The second of these areas is approximately 2,630 yards by 160 yards, encompasses 89.90... on their vessels at night. Leaving their lights on overnight could result in dead batteries...

  7. 78 FR 59914 - Foreign-Trade Zone 160-Anchorage, Alaska; Application for Reorganization Under Alternative Site...

    Science.gov (United States)

    2013-09-30

    ... with the FTZ Board's regulations, Christopher Kemp of the FTZ Staff is designated examiner to evaluate... the foregoing period may be submitted during the subsequent 15- day period to December 16, 2013. A... accessible via www.trade.gov/ftz . For further information, contact Christopher Kemp at...

  8. H08844: NOS Hydrographic Survey , Key West Naval Anchorage Area, Florida, 1965-10-15

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  9. Zakorzenienie umysłu w obiektach abstrakcyjnych (The Mind's Anchorage in Abstract Objects

    Directory of Open Access Journals (Sweden)

    Robert Piłat

    2010-06-01

    Full Text Available Some features of human linguistic competence make one to reconsider the Fregean notion of modes of presentation, which were supposed to correspond to senses of words. Especially two linguistic phenomena invite such a reflection: (1 generalized reports about people`s beliefs, like "Everybody thinks that p"; (2 semantic relations (like synonymy between empty names (proper or general. In the analysis of belief reports I am referring to studies by Edward Zalta; in the analysis of empty names I am drawing on Jerrold Katz and Georges Rey`s accounts. The three entirely independent inquiries seem to support the claim, that Fregean senses (understood as the modes of presentation presuppose the existence of abstract individuals and properties, which are intuitively apprehend by the speakers. It leads to certain conclusion about the nature of the human mind. In this article I am arguing that to the extent determined by the analyzed phenomena, human mind is in part an abstract entity - it incorporates - as its parts - the abstract entities though which it is referring to itself. This reference to oneself takes place in virtue of possessing ones own thoughts. Possessing thoughts is quite different from having experiences or more generally, psychological states. It requires that a subject is related to certain abstract objects. Although I do not believe that this claim amounts to some sort of spiritualism, I do believe that it imposes rather serious constraint on naturalistic accounts of the mind. This view is committed to rather strong form of emergentism or even to some kind of interactive dualism about the mind.

  10. A screen for deficiencies in GPI-anchorage of wall glycoproteins in yeast.

    Science.gov (United States)

    Gonzalez, Marlyn; Goddard, Noel; Hicks, Charles; Ovalle, Rafael; Rauceo, Jason M; Jue, Chong K; Lipke, Peter N

    2010-08-01

    Many of the genes and enzymes critical for assembly and biogenesis of yeast cell walls remain unidentified or poorly characterized. Therefore, we designed a high throughput genomic screen for defects in anchoring of GPI-cell wall proteins (GPI-CWPs), based on quantification of a secreted GFP-Sag1p fusion protein. Saccharomyces cerevisiae diploid deletion strains were transformed with a plasmid expressing the fusion protein under a GPD promoter, then GFP fluorescence was determined in culture supernatants after mid-exponential growth. Variability in the amount of fluorescent marker secreted into the medium was reduced by growth at 18 degrees C in buffered defined medium in the presence of sorbitol. Secondary screens included immunoblotting for GFP, fluorescence emission spectra, cell surface fluorescence, and cell integrity. Of 167 mutants deleted for genes affecting cell wall biogenesis or structure, eight showed consistent hyper-secretion of GFP relative to parental strain BY4743: tdh3 (glyceraldehyde-3-phosphate dehydrogenase), gda1 (guanosine diphosphatase), gpi13 and mcd4 (both ethanolamine phosphate-GPI-transferases), kre5 and kre1 (involved in synthesis of beta1,6 glucan), dcw1(implicated in GPI-CWP cross-linking to cell wall glucan), and cwp1 (a major cell wall protein). In addition, deletion of a number of genes caused decreased secretion of GFP. These results elucidate specific roles for specific genes in cell wall biogenesis, including differentiating among paralogous genes.

  11. 77 FR 47864 - Ocean Energy Safety Advisory Committee (OESC); Notice of Meeting

    Science.gov (United States)

    2012-08-10

    .... SUMMARY: OESC will meet at the Anchorage Marriott Downtown Hotel in Anchorage, Alaska. DATES: Wednesday...: Anchorage Marriott Downtown Hotel, 820 West 7th Avenue, Anchorage, Alaska 99501. FOR FURTHER...

  12. Brief introduction to worldwide test types of anchorage%国内外锚杆试验类型简介

    Institute of Scientific and Technical Information of China (English)

    付文光

    2014-01-01

    There are three test types of ground anchor such as basic test, creep test and acceptance test in China, and performance test, proof test and extended creep test in US, and investigation test, suitability test and acceptance test in EU. In addition, there are some tests for some determinate aspects of anchor performance in US and EU such as lift-off test, oscillating load test, testing of corrosion protection, test for cyclic work load, etc. The demands for anchor tests in US code is relatively simpler while more strict and precise in EU code. The meaning and function of basic tests on anchor attract no enough attention in China. It should be more zetetic but not proof for testing and understanding the anchor performances more adequately.%国内锚杆试验类型分为基本试验、蠕变试验及验收试验3类,美国分为性能试验、验证试验及延长蠕变试验3类,欧洲分为探究试验、适应试验及验收试验3类,此外欧美还有提离试验、交变荷载试验、腐蚀防护完整性试验、确定波动荷载下最大工作荷载的试验等一些检测锚杆某些方面性能的试验。相对而言,美国标准对锚杆试验的要求简单一些,欧洲的更严格、更严谨一些。国内工程中,对锚杆基本试验的意义与作用尚重视不够,应把其作为探究性试验而非验证性试验,以便能够更为充分地测试及了解锚杆的性能。

  13. Treatment of Class II malocclusion with bialveolar protrusion by means of unusual extractions and anchorage mini-implant

    OpenAIRE

    Jong-Moon Chae

    2012-01-01

    INTRODUCTION: Patients with dental Class II bialveolar protrusion are generally treated by extracting the four first premolars or two first and two second premolars, and retracting the anterior teeth. This case report describes the treatment of an adult patient with bialveolar protrusion, a Class II canine and molar relationship, and lip protrusion. METHODS: In this patient, the maxillary right second molar (1.7) had to be extracted due to extensive caries. To create sufficient space to retra...

  14. Intrusão dentária utilizando mini-implantes Orthodontic intrusion with mini-implant anchorage

    OpenAIRE

    Telma Martins de Araújo; Mauro Henrique Andrade Nascimento; Fernanda Catharino Menezes Franco; Marcos Alan Vieira Bittencourt

    2008-01-01

    INTRODUÇÃO: dentre os diversos tipos de movimentos dentários induzidos ortodonticamente, o de intrusão é, sem dúvida, um dos mais difíceis de serem conseguidos. A mecânica intrusiva convencional, apesar de viável, é complexa, no que diz respeito ao controle de seus efeitos colaterais. Isso, em grande parte, refere-se à dificuldade em se obter uma ancoragem satisfatória. Neste contexto, os mini-implantes, por oferecerem efetiva ancoragem esquelética, têm se mostrado de extrema valia para os or...

  15. Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

    Directory of Open Access Journals (Sweden)

    Jun Chen

    2000-05-01

    Full Text Available Survivin, a member of the inhibitor of apoptosis protein (IAP family, is detected in most common human cancers but not in adjacent normal cells. Previous studies suggest that survivin associates with the mitotic spindle and directly inhibits caspase activity. To further investigate the function of survivin, we used a survivin antisense (AS oligonucleotide to downregulate survivin expression in normal and cancer cells. We found that inhibition of survivin expression increased apoptosis and polyploidy while decreasing colony formation in soft agar. Immunohistochemistry showed that cells without survivin can initiate the cleavage furrow and contractile ring, but cannot complete cytokinesis, thus resulting in multinucleated cells. These findings indicate that survivin plays important roles in a late stage of cytokinesis, as well as in apoptosis.

  16. 76 FR 20287 - Superfund Site, New Bedford Harbor, New Bedford, MA: Anchorage Ground and Regulated Navigation Area

    Science.gov (United States)

    2011-04-12

    ... New Bedford Harbor hurricane barrier in the outer harbor. The pilot cap consists of sand and gravel... revising paragraph (a)(2) to read as follows: Sec. 110.140 Buzzards Bay, Nantucket Sound, and...

  17. Evaluating the effects of consolidation on intrusion and retraction using temporary anchorage devices—a FEM study

    Directory of Open Access Journals (Sweden)

    Monica Namburi

    2017-01-01

    Full Text Available Abstract Background Extraction of premolars and retracting the anterior teeth using mini-implants and anterior retraction hooks became advent now a day. In such treatments, consolidation of arches is not done in regular practice. So, the present study is concentrated on effects of consolidation in two implant and three implant combinations of retraction and intrusion. Methods A three-dimensional FEM model of maxillary teeth and periodontal ligament housed in the alveolar bone with the first premolars extracted is generated with appropriate number of elements and nodes. The models were broadly divided into two groups according to the no. of implants. Mini-implants were placed bilaterally between the second premolar and molar at varying heights (7, 10, 13 mm in group I, and along with bilateral implants, an additional mid-implant is placed between the central incisors as group II. Brackets with 0.022 slot were placed on the teeth, 19 × 25 SS wire is placed in the brackets, an anterior retraction hook was placed at 9 mm height, and analysis was done to evaluate the stresses and displacement patterns in consolidation and non-consolidation models. Results The results showed that consolidation of the anterior teeth during intrusion and retraction shows various advantages such as less stresses on the bone, PDL, implant, teeth, and no labial flaring of the anterior teeth and three implant system, i.e., two bilateral implant at 10 mm and a mid-implant at 12 mm between the centrals has shown to be better than other models as bodily movement is observed. Conclusion Consolidation is better than non consolidation during enmasse retraction and intrusion.

  18. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Mack, Hildegard I.D.; Munger, Karl, E-mail: kmunger@rics.bwh.harvard.edu

    2013-11-15

    Infection with high-risk human papillomaviruses is causally linked to cervical carcinogenesis. However, most lesions caused by high-risk HPV infections do not progress to cancer. Host cell mutations contribute to malignant progression but the molecular nature of such mutations is unknown. Based on a previous study that reported an association between liver kinase B1 (LKB1) tumor suppressor loss and poor outcome in cervical cancer, we sought to determine the molecular basis for this observation. LKB1-negative cervical and lung cancer cells were reconstituted with wild type or kinase defective LKB1 mutants and we examined the importance of LKB1 catalytic activity in known LKB1-regulated processes including inhibition of cell proliferation and elevated resistance to energy stress. Our studies revealed marked differences in the biological activities of two kinase defective LKB1 mutants in the various cell lines. Thus, our results suggest that LKB1 may be a cell-type specific tumor suppressor. - Highlights: • LKB1 is a tumor suppressor that is linked to Peutz-Jeghers syndrome. • Peutz-Jeghers syndrome patients have a high incidence of cervical cancer. • Cervical cancer is caused by HPV infections. • This study investigates LKB1 tumor suppressor activity in cervical cancer.

  19. Treatment Approach for Maxillary Hypoplasia in Cleft Patients: Class III Elastics with Skeletal Anchorage (Report of Two Cases

    Directory of Open Access Journals (Sweden)

    Arezoo Jahanbin

    2016-05-01

    Full Text Available Introduction: Treatment ofcleft lip and palate patients requires a multidisciplinary plan. These patients usually have a hypoplastic maxilla due to the prior surgical scars. Orthognathic surgery to advance the maxilla in these patients is not very efficient; therefore, orthopedic interventions during an appropriate age seems to be essential.   Case Report: In this article, two cleft lip and palate patients have been treated with Class III elastics anchored to the maxillary posterior and mandibular anterior miniplates in order to induce maxillary advancement.   Conclusion: Both cases showed a significant improvement in their profiles with minimal dentoalveolar compensations. A counterclockwise rotation of the mandible occurred.

  20. Treatment Approach for Maxillary Hypoplasia in Cleft Patients: Class III Elastics with Skeletal Anchorage (Report of Two Cases)

    Science.gov (United States)

    Jahanbin, Arezoo; Kazemian, Mozhgan; Saeedi-Pouya, Iman; Eslami, Neda; Shafaee, Hooman

    2016-01-01

    Introduction: Treatment of cleft lip and palate patients requires a multidisciplinary plan. These patients usually have a hypoplastic maxilla due to the prior surgical scars. Orthognathic surgery to advance the maxilla in these patients is not very efficient; therefore, orthopedic interventions during an appropriate age seems to be essential. Case Report: In this article, two cleft lip and palate patients have been treated with Class III elastics anchored to the maxillary posterior and mandibular anterior miniplates in order to induce maxillary advancement. Conclusion: Both cases showed a significant improvement in their profiles with minimal dentoalveolar compensations. A counterclockwise rotation of the mandible occurred. PMID:27602343

  1. Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

    Directory of Open Access Journals (Sweden)

    Martin F Dietrich

    Full Text Available BACKGROUND: The low-density lipoprotein (LDL receptor gene family is a highly conserved group of membrane receptors with diverse functions in developmental processes, lipoprotein trafficking, and cell signaling. The low-density lipoprotein (LDL receptor-related protein 1b (LRP1B was reported to be deleted in several types of human malignancies, including non-small cell lung cancer. Our group has previously reported that a distal extracellular truncation of murine Lrp1b that is predicted to secrete the entire intact extracellular domain (ECD is fully viable with no apparent phenotype. METHODS AND PRINCIPAL FINDINGS: Here, we have used a gene targeting approach to create two mouse lines carrying internally rearranged exons of Lrp1b that are predicted to truncate the protein closer to the N-terminus and to prevent normal trafficking through the secretary pathway. Both mutations result in early embryonic lethality, but, as expected from the restricted expression pattern of LRP1b in vivo, loss of Lrp1b does not cause cellular lethality as homozygous Lrp1b-deficient blastocysts can be propagated normally in culture. This is similar to findings for another LDL receptor family member, Lrp4. We provide in vitro evidence that Lrp4 undergoes regulated intramembraneous processing through metalloproteases and gamma-secretase cleavage. We further demonstrate negative regulation of the Wnt signaling pathway by the soluble extracellular domain. CONCLUSIONS AND SIGNIFICANCE: Our results underline a crucial role for Lrp1b in development. The expression in mice of truncated alleles of Lrp1b and Lrp4 with deletions of the transmembrane and intracellular domains leads to release of the extracellular domain into the extracellular space, which is sufficient to confer viability. In contrast, null mutations are embryonically (Lrp1b or perinatally (Lrp4 lethal. These findings suggest that the extracellular domains of both proteins may function as a scavenger for signaling ligands or signal modulators in the extracellular space, thereby preserving signaling thresholds that are critical for embryonic development, as well as for the clear, but poorly understood role of LRP1b in cancer.

  2. 78 FR 11745 - Anchorages; Lower Mississippi River, Above Head of Passes, Convent, LA and Point Pleasant, LA

    Science.gov (United States)

    2013-02-20

    ... ``entrainment issues associated with dredging operations in the Mississippi and Atchafalaya Rivers and through..., and does not require an assessment of potential costs and benefits under section 6(a)(3) of Executive... amended, requires federal agencies to consider the potential impact of regulations on small...

  3. Accelerated Sorption Diffusion for Cu(II) Retention by Anchorage of Nano-zirconium Dioxide onto Highly charged Polystyrene Material

    Science.gov (United States)

    Zhang, Qingrui; Du, Qing; Jiao, Tifeng; Teng, Jie; Sun, Qina; Peng, Qiuming; Chen, Xinqing; Gao, Faming

    2015-01-01

    The development of nanocomposite with strong adsorption ability exhibits great potential applications for environmental remediation. However, the pore blocking in preparation frequently constrains sorption diffusion, resulting in low utilization efficiency. Here we synthesized a new nano-ZrO2/Polystyrene (NZO-PS) material tailored with a specific fixed SO3-Na group to enhance Cu(II) removal. The NZO-PS exhibits efficient Cu(II) sequestration in a wide pH range (3.0–6.5) and preferential sorption performances. The efficient kinetic behavior and column applicability suggest the blocked pore channel is not a matter when presence of negatively charged moiety, which accelerates Cu(II) sorption diffusion and enrichment toward target active site. Moreover, the exhausted NZO-PS can be readily regenerated through HCl-NaCl binary solution. The preparation route can be extended to synthesize other functional composited materials. Simultaneously, the characteristics of simplicity, high-yield and regeneration provide some promising industrial merits. PMID:26184921

  4. Treatability Study in Support of Intrinsic Remediation for Site ST41. Elmendorf Air Force Base, Anchorage, Alaska

    Science.gov (United States)

    1995-10-01

    finl.doc *00 ST41-82802 T4-2 I0 AOP 0 ST4-32 ST5 ST41-MWEs8 ST --S-- ---. M00 C0 7 ST41f~ -ES -1ST10 ST4 41 - ESSB 0-0 LE D S . 4T41 -S8 0 504E 10...ST41- ESSB 0.006 p ST41-ES7A 1.553 ST41-ES7B 0.194 ’ LAB DUP 0.180 ST4- 5S8A 0.811 ST41-ES8B 0.007 SP7/10-02 0.001 ’FIELD DUP 0.001 ANALYZED 6/29/94

  5. F00437A: NOS Hydrographic Survey , Delaware Bay, Delaware, Vicinity of Big Stone Anchorage Area, 1997-11-17

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  6. F00437B: NOS Hydrographic Survey , Delaware Bay, Delaware, Vicinity of Big Stone Anchorage Area, 1997-11-17

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  7. Chloroplast outer envelope protein CHUP1 is essential for chloroplast anchorage to the plasma membrane and chloroplast movement.

    Science.gov (United States)

    Oikawa, Kazusato; Yamasato, Akihiro; Kong, Sam-Geun; Kasahara, Masahiro; Nakai, Masato; Takahashi, Fumio; Ogura, Yasunobu; Kagawa, Takatoshi; Wada, Masamitsu

    2008-10-01

    Chloroplasts change their intracellular distribution in response to light intensity. Previously, we isolated the chloroplast unusual positioning1 (chup1) mutant of Arabidopsis (Arabidopsis thaliana). This mutant is defective in normal chloroplast relocation movement and shows aggregation of chloroplasts at the bottom of palisade mesophyll cells. The isolated gene encodes a protein with an actin-binding motif. Here, we used biochemical analyses to determine the subcellular localization of full-length CHUP1 on the chloroplast outer envelope. A CHUP1-green fluorescent protein (GFP) fusion, which was detected at the outermost part of mesophyll cell chloroplasts, complemented the chup1 phenotype, but GFP-CHUP1, which was localized mainly in the cytosol, did not. Overexpression of the N-terminal hydrophobic region (NtHR) of CHUP1 fused with GFP (NtHR-GFP) induced a chup1-like phenotype, indicating a dominant-negative effect on chloroplast relocation movement. A similar pattern was found in chloroplast OUTER ENVELOPE PROTEIN7 (OEP7)-GFP transformants, and a protein containing OEP7 in place of NtHR complemented the mutant phenotype. Physiological analyses of transgenic Arabidopsis plants expressing truncated CHUP1 in a chup1 mutant background and cytoskeletal inhibitor experiments showed that the coiled-coil region of CHUP1 anchors chloroplasts firmly on the plasma membrane, consistent with the localization of coiled-coil GFP on the plasma membrane. Thus, CHUP1 localization on chloroplasts, with the N terminus inserted into the chloroplast outer envelope and the C terminus facing the cytosol, is essential for CHUP1 function, and the coiled-coil region of CHUP1 prevents chloroplast aggregation and participates in chloroplast relocation movement.

  8. Remedial Investigation/Feasibility Study, Operable Unit 5, Elmendorf AFB, Anchorage, Alaska. Volume 2. Text and Appendices A - J

    Science.gov (United States)

    1994-03-04

    of Wedge-tailed Shearwaters Exposed to Weathered Santa Barbara Crude Oil." Arch. Environ. Contain. Toxicol. 15:453-463. Fry, D. M., And L. J...144894N64E. 442-Dlex Nd i WodServi Pole _______ ______ _______N26’W. 9.DulxNmAl in Sottbasta carper of OU5SB-24 ft 2.643.055.23 1.670.72D.22 141.1 S66’W

  9. 76 FR 39386 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage...

    Science.gov (United States)

    2011-07-06

    ... tide; (5) in-water piles will be driven with a vibratory hammer to the maximum extent possible (i.e., until a desired depth is achieved or to refusal) prior to using an impact hammer; (6) in-water pile... vitulina), by Level B harassment, incidental to in-water pile driving were issued on July 15, 2009 (74...

  10. IMPROVED TISSUE INGROWTH AND ANCHORAGE OF EXPANDED POLYTETRAFLUOROETHYLENE BY PERFORATION - AN EXPERIMENTAL-STUDY IN THE RAT

    NARCIS (Netherlands)

    SIMMERMACHER, RKJ; VANDERLEI, B; SCHAKENRAAD, JM; BLEICHRODT, RP

    1991-01-01

    Although an expanded polytetrafluoroethylene patch is a suitable synthetic material to repair large abdominal wall defects, lack of tissue ingrowth into the patch may give rise to herniation at the fascia-patch interface. This study was undertaken to determine whether perforations and/or ethanol pre

  11. Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm.

    Science.gov (United States)

    Tanaka, Tsubasa; Kato, Yasuko; Matsuda, Kazuki; Hanyu-Nakamura, Kazuko; Nakamura, Akira

    2011-06-01

    Drosophila pole (germ) plasm contains germline and abdominal determinants. Its assembly begins with the localization and translation of oskar (osk) RNA at the oocyte posterior, to which the pole plasm must be restricted for proper embryonic development. Osk stimulates endocytosis, which in turn promotes actin remodeling to form long F-actin projections at the oocyte posterior pole. Although the endocytosis-coupled actin remodeling appears to be crucial for the pole plasm anchoring, the mechanism linking Osk-induced endocytic activity and actin remodeling is unknown. Here, we report that a Golgi-endosomal protein, Mon2, acts downstream of Osk to remodel cortical actin and to anchor the pole plasm. Mon2 interacts with two actin nucleators known to be involved in osk RNA localization in the oocyte, Cappuccino (Capu) and Spire (Spir), and promotes the accumulation of the small GTPase Rho1 at the oocyte posterior. We also found that these actin regulators are required for Osk-dependent formation of long F-actin projections and cortical anchoring of pole plasm components. We propose that, in response to the Osk-mediated endocytic activation, vesicle-localized Mon2 acts as a scaffold that instructs the actin-remodeling complex to form long F-actin projections. This Mon2-mediated coupling event is crucial to restrict the pole plasm to the oocyte posterior cortex.

  12. 75 FR 38465 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage...

    Science.gov (United States)

    2010-07-02

    ..., when ice formation and poor visibility impeded further activity. These activities were within the scope... stationed at the port during all in-water pile driving and chipping and blasting associated with...

  13. Measurement of strain distribution in cortical bone around miniscrew implants used for orthodontic anchorage using digital speckle pattern interferometry

    Science.gov (United States)

    Kumar, Manoj; Agarwal, Rupali; Bhutani, Ravi; Shakher, Chandra

    2016-05-01

    An application of digital speckle pattern interferometry (DSPI) for the measurement of deformations and strain-field distributions developed in cortical bone around orthodontic miniscrew implants inserted into the human maxilla is presented. The purpose of this study is to measure and compare the strain distribution in cortical bone/miniscrew interface of human maxilla around miniscrew implants of different diameters, different implant lengths, and implants of different commercially available companies. The technique is also used to measure tilt/rotation of canine caused due to the application of retraction springs. The proposed technique has high sensitivity and enables the observation of deformation/strain distribution. In DSPI, two specklegrams are recorded corresponding to pre- and postloading of the retraction spring. The DSPI fringe pattern is observed by subtracting these two specklegrams. Optical phase was extracted using Riesz transform and the monogenic signal from a single DSPI fringe pattern. The obtained phase is used to calculate the parameters of interest such as displacement/deformation and strain/stress. The experiment was conducted on a dry human skull fulfilling the criteria of intact dental arches and all teeth present. Eight different miniscrew implants were loaded with an insertion angulation of 45 deg in the inter-radicular region of the maxillary second premolar and molar region. The loading of miniscrew implants was done with force level (150 gf) by nickel-titanium closed-coil springs (9 mm). The obtained results from DSPI reveal that implant diameter and implant length affect the displacement and strain distribution in cortical bone layer surrounding the miniscrew implant.

  14. KSHV MicroRNAs Repress Tropomyosin 1 and Increase Anchorage-Independent Growth and Endothelial Tube Formation.

    Directory of Open Access Journals (Sweden)

    Philippe Kieffer-Kwon

    Full Text Available Kaposi's sarcoma (KS is characterized by highly vascularized spindle-cell tumors induced after infection of endothelial cells by Kaposi's sarcoma-associated herpesvirus (KSHV. In KS tumors, KSHV expresses only a few latent proteins together with 12 pre-microRNAs. Previous microarray and proteomic studies predicted that multiple splice variants of the tumor suppressor protein tropomyosin 1 (TPM1 were targets of KSHV microRNAs. Here we show that at least two microRNAs of KSHV, miR-K2 and miR-K5, repress protein levels of specific isoforms of TPM1. We identified a functional miR-K5 binding site in the 3' untranslated region (UTR of one TPM1 isoform. Furthermore, the inhibition or loss of miR-K2 or miR-K5 restores expression of TPM1 in KSHV-infected cells. TPM1 protein levels were also repressed in KSHV-infected clinical samples compared to uninfected samples. Functionally, miR-K2 increases viability of unanchored human umbilical vein endothelial cells (HUVEC by inhibiting anoikis (apoptosis after cell detachment, enhances tube formation of HUVECs, and enhances VEGFA expression. Taken together, KSHV miR-K2 and miR-K5 may facilitate KSHV pathogenesis.

  15. 33 CFR 110.238 - Apra Harbor, Guam.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. 110.238 Section 110.238 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.238 Apra Harbor, Guam. (a) The anchorage grounds (Datum: WGS 84). (1) General Anchorage. The...

  16. Libraries in Alaska: MedlinePlus

    Science.gov (United States)

    ... this page: https://medlineplus.gov/libraries/alaska.html Libraries in Alaska To use the sharing features on ... JavaScript. Anchorage University of Alaska Anchorage Alaska Medical Library 3211 Providence Drive Anchorage, AK 99508-8176 907- ...

  17. Class III malocclusion with complex problems of lateral open bite and severe crowding successfully treated with miniscrew anchorage and lingual orthodontic brackets.

    Science.gov (United States)

    Yanagita, Takeshi; Kuroda, Shingo; Takano-Yamamoto, Teruko; Yamashiro, Takashi

    2011-05-01

    In this article, we report the successful use of miniscrews in a patient with an Angle Class III malocclusion, lateral open bite, midline deviation, and severe crowding. Simultaneously resolving such problems with conventional Class III treatment is difficult. In this case, the treatment procedure was even more challenging because the patient preferred to have lingual brackets on the maxillary teeth. As a result, miniscrews were used to facilitate significant asymmetric tooth movement in the posterior and downward directions; this contributed to the camouflage of the skeletal mandibular protrusion together with complete resolution of the severe crowding and lateral open bite. Analysis of the jaw motion showed that irregularities in chewing movement were also resolved, and a stable occlusion was achieved. Improvements in the facial profile and dental arches remained stable at the 18-month follow-up.

  18. Mesialização de molares com ancoragem em mini-implantes Mesial movement of molars with mini-implants anchorage

    OpenAIRE

    Marcos Janson; Daniela Alcântara Fernandes Silva

    2008-01-01

    INTRODUÇÃO: é muito comum, na rotina do consultório odontológico, especialmente em Ortodontia, o paciente, após avaliar o plano de tratamento proposto, questionar sobre a possibilidade de fechamento de espaços presentes, ocasionados pela perda de dentes permanentes. O ortodontista, frente a essa questão, tem que avaliar diversos fatores, tais como a má oclusão presente, a integridade do osso e das raízes, o tempo de tratamento e a geometria do posicionamento dentário, que é o que permite aval...

  19. Missense mutations in pyruvate kinase M2 promote cancer metabolism, oxidative endurance, anchorage independence, and tumor growth in a dominant negative manner.

    Science.gov (United States)

    Iqbal, Mohd Askandar; Siddiqui, Farid Ahmad; Chaman, Noor; Gupta, Vibhor; Kumar, Bhupender; Gopinath, Prakasam; Bamezai, Rameshwar N K

    2014-03-21

    The present study was designed to examine the functional relevance of two heterozygous mutations (H391Y and K422R), observed earlier by us in the Bloom syndrome condition. Cells stably expressing exogenous wild-type or mutant PKM2 (K422R or H391Y) or co-expressing both wild type and mutant (PKM2-K422R or PKM2-H391Y) were assessed for cancer metabolism and tumorigenic potential. Interestingly, cells co-expressing PKM2 and mutant (K422R or H391Y) showed significantly aggressive cancer metabolism as compared with cells expressing either wild-type or mutant PKM2 independently. A similar trend was observed for oxidative endurance, tumorigenic potential, cellular proliferation, and tumor growth. These observations signify the dominant negative nature of mutations. Remarkably, PKM2-H391Y co-expressed cells showed a maximal effect on all the studied parameters. Such a dominant negative impaired function of PKM2 in tumor development is not known; this study demonstrates for the first time the possible predisposition of Bloom syndrome patients with impaired PKM2 activity to cancer and the importance of studying genetic variations in PKM2 in the future to understand their relevance in cancer in general.

  20. Correction of a Class III malocclusion with over 20 mm of space to close in the maxilla by using miniscrews for extra anchorage.

    NARCIS (Netherlands)

    Breuning, K.H.

    2008-01-01

    Unilateral closure of maxillary extraction spaces in patients with Class III malocclusion can be challenging. This case report describes the closure of first premolar and first molar extraction spaces in a patient with a Class III dental relationship. Two miniscrews were used for intraoral skeletal

  1. Improved anchorage of Ti6Al4V orthopaedic bone implants through oligonucleotide mediated immobilization of BMP-2 in osteoporotic rats.

    Directory of Open Access Journals (Sweden)

    Julia V Wölfle

    Full Text Available The aim of the present study was to test the biocompatibility and functionality of orthopaedic bone implants with immobilized oligonucleotides serving as anchor stands for rhBMP-2 and rhVEGF-A conjugated with complementary oligonucleotides in an osteoporotic rat model. Al2O3-blasted acid etched Ti6Al4V implants, carrying oligonucleotide anchor strands and hybridized with rhBMP-2 or rhVEGF-A through complementary 31-mer oligonucleotide stands were inserted into the proximal tibia of ovariectomized rats. At the time of surgery (15 weeks after ovariectomy microCT analysis showed significantly lower bone mineral density compared to non-ovariectomized animals. Bone-implant contact (BIC and pullout-force were not negatively affected by non-hybridized anchor strands. Twelve weeks after surgery, a significantly higher pullout force was found for BMP-2 hybridized to the anchor strands compared to non-hybridized anchor strands or native samples, and on histomorphometric analysis BIC was highest in the BMP group. Thus, we could show the biocompatibility and in vivo functionality of this modular, self-organizing system for immobilization and subsequent release of BMP-2 in vivo.

  2. Improved Anchorage of Ti6Al4V Orthopaedic Bone Implants through Oligonucleotide Mediated Immobilization of BMP-2 in Osteoporotic Rats

    Science.gov (United States)

    Wölfle, Julia V.; Fiedler, Jörg; Dürselen, Lutz; Reichert, Judith; Scharnweber, Dieter; Förster, Anne; Schwenzer, Bernd; Reichel, Heiko; Ignatius, Anita; Brenner, Rolf E.

    2014-01-01

    The aim of the present study was to test the biocompatibility and functionality of orthopaedic bone implants with immobilized oligonucleotides serving as anchor stands for rhBMP-2 and rhVEGF-A conjugated with complementary oligonucleotides in an osteoporotic rat model. Al2O3-blasted acid etched Ti6Al4V implants, carrying oligonucleotide anchor strands and hybridized with rhBMP-2 or rhVEGF-A through complementary 31-mer oligonucleotide stands were inserted into the proximal tibia of ovariectomized rats. At the time of surgery (15 weeks after ovariectomy) microCT analysis showed significantly lower bone mineral density compared to non-ovariectomized animals. Bone-implant contact (BIC) and pullout-force were not negatively affected by non-hybridized anchor strands. Twelve weeks after surgery, a significantly higher pullout force was found for BMP-2 hybridized to the anchor strands compared to non-hybridized anchor strands or native samples, and on histomorphometric analysis BIC was highest in the BMP group. Thus, we could show the biocompatibility and in vivo functionality of this modular, self-organizing system for immobilization and subsequent release of BMP-2 in vivo. PMID:24465929

  3. A Novel Rat Model of Orthodontic Tooth Movement Using Temporary Skeletal Anchorage Devices: 3D Finite Element Analysis and In Vivo Validation

    Science.gov (United States)

    Stevenson, Thomas; Doschak, Michael

    2014-01-01

    The aim of this animal study was to develop a model of orthodontic tooth movement using a microimplant as a TSAD in rodents. A finite element model of the TSAD in alveolar bone was built using μCT images of rat maxilla to determine the von Mises stresses and displacement in the alveolar bone surrounding the TSAD. For in vivo validation of the FE model, Sprague-Dawley rats (n = 25) were used and a Stryker 1.2 × 3 mm microimplant was inserted in the right maxilla and used to protract the right first permanent molar using a NiTi closed coil spring. Tooth movement measurements were taken at baseline, 4 and 8 weeks. At 8 weeks, animals were euthanized and tissues were analyzed by histology and EPMA. FE modeling showed maximum von Mises stress of 45 Mpa near the apex of TSAD but the average von Mises stress was under 25 Mpa. Appreciable tooth movement of 0.62 ± 0.04 mm at 4 weeks and 1.99 ± 0.14 mm at 8 weeks was obtained. Histological and EPMA results demonstrated no active bone remodeling around the TSAD at 8 weeks depicting good secondary stability. This study provided evidence that protracted tooth movement is achieved in small animals using TSADs. PMID:25295060

  4. Prestressed anchorage cable construction technique and unit price analysis%预应力锚索施工技术及单价分析

    Institute of Scientific and Technical Information of China (English)

    王家海

    2003-01-01

    预应力锚索技术是一种新加固土体技术,在铁路的高路堑边坡加固工程中得到越来越广泛的应用.笔者结合现场施工的实际经验,简要介绍了预应力锚索技术施工工序及单价分析.

  5. Fibronectin has a dual role in locomotion and anchorage of primary chick fibroblasts and can promote entry into the division cycle

    DEFF Research Database (Denmark)

    Couchman, J R; Rees, D A; Green, M R

    1982-01-01

    microscopy with a colloidal gold marker reveals the presence of small membrane-associated plaques of fibronectin in motile cells with associated submembranous specialization. A fibrillar matrix containing fibronectin is dominant in nonmotile, growing fibroblasts. The development of focal adhesions...

  6. 33 CFR 110.240 - San Juan Harbor, P.R.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false San Juan Harbor, P.R. 110.240 Section 110.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.240 San Juan Harbor, P.R. (a) The anchorage...

  7. 33 CFR 110.255 - Ponce Harbor, P.R.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Ponce Harbor, P.R. 110.255 Section 110.255 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.255 Ponce Harbor, P.R. (a) Small-craft anchorage. On...

  8. 33 CFR 110.142 - Nantucket Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Nantucket Harbor, Mass. 110.142 Section 110.142 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.142 Nantucket Harbor, Mass. (a) The anchorage grounds. In...

  9. 33 CFR 110.208 - Buffalo Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo Harbor, N.Y. 110.208 Section 110.208 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.208 Buffalo Harbor, N.Y. (a) The anchorage...

  10. 33 CFR 110.150 - Block Island Sound, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Block Island Sound, N.Y. 110.150 Section 110.150 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.150 Block Island Sound, N.Y. (a) The anchorage ground. A...

  11. 33 CFR 110.210 - San Diego Harbor, CA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false San Diego Harbor, CA. 110.210... ANCHORAGE REGULATIONS Anchorage Grounds § 110.210 San Diego Harbor, CA. (a) The anchorage grounds. (1... Commander, Naval Base, San Diego, CA. The administration of these anchorages is exercised by the...

  12. 大直径螺柱焊在660kW风电地锚生产中的应用%Application of the large diameter stud welding in production of 660 kW windturbine anchorage

    Institute of Scientific and Technical Information of China (English)

    刘志颖; 赵宁; 曲俊霞

    2003-01-01

    通过螺柱焊技术在660 kW风力发电机组焊接结构件中的应用,对螺柱焊接的工艺焊接性和使用焊接性进行了探讨和论证.在实际生产过程中采集了大量试样进行加工试验.结果表明:螺柱焊技术在风电地锚生产应用中的加工适应性是良好的,能够获得优质的焊接接头,两种不同性质钢材的螺柱焊接头在产品设计要求的低温条件下可靠运行.

  13. EXPERIMENTAL STUDY ON BOND-ANCHORAGE OF HOT ROLLED RIBBED BARS OF FINE GRAINS IN CONCRETE%细晶粒热轧带肋钢筋粘结锚固性能试验研究

    Institute of Scientific and Technical Information of China (English)

    刘立新; 李殿文; 陈萌

    2011-01-01

    细晶粒热轧带肋钢筋是我国冶金行业研究开发的强度高、延性好的新型热轧钢筋,其抗拉屈服强度标准值为500 MPa.通过25组75个直径8~25 mm的细晶粒热轧带肋钢筋与混凝土粘结锚同试件的拔出试验,分析了混凝土强度、锚固长度、钢筋直径、保护层厚度、横向配箍率等因素对细晶粒热轧带肋钢筋与混凝土粘结锚固件能的影响.结果表明,细品粒热轧带肋钢筋在混凝土中的锚固性能与普通热轧带肋钢筋基本相同,其用于混凝土结构中的设计锚固长度仍可按现行GB 50010-2002的规定计算,为细晶粒热轧带肋钢筋的工程应用提供了依据.

  14. 汽车座椅安全带固定点强度试验仿真模型改进%Simulation Model Improvement of Vehicle Seatbelt Anchorage Strength

    Institute of Scientific and Technical Information of China (English)

    曹奇; 成艾国; 周泽; 吴飞

    2012-01-01

    通过对比分析有限元理论中显式积分和隐式积分两种方法的优劣,针对汽车座椅安全带拉伸试验这一准静态过程,选用LS-DYNA显式有限元程序建立国产某车型汽车安全带分析模型,通过对传统模型中单元类型、计算时间、加载曲线等关键参数进行优化,逐步提高计算仿真结果与实车安全带拉伸试验的吻合度。研究结果为优化建模精度,提高预测准确度,并进一步优化车身结构提供了较好的思路。%This paper compared explicit integration and implicit integration metnoo in finite element method. As to the vehicle safebelt experiment which was a quasi-static problem, explicit integration method was selected. Then,a FE model was built to simulate this process. To get a fine model to forecast the test results,lots of studies and optimizations on some key parameters such as the element section type, calculation time, and load curve were carried out herein. Thus a more precision model was acquired whose results are very close to the actual experiments. This paper gives some useful conclusions on improving model parameters, simulation accuracy and optimization of the vehicle body structure.

  15. 基于LS-DYNA的安全带固定点强度试验仿真精度研究%SIMULATION ACCURACY STUDY ON THE STRENGTH TEST OF SEATBELTS ANCHORAGES BASED ON LS-DYNA

    Institute of Scientific and Technical Information of China (English)

    郑松林; 王肖龙; 李应军; 安超群

    2015-01-01

    针对安全带固定点强度试验这一准静态过程,通过对比分析弹性动力学中中心差分法(显式)和Newmark法(隐式)的优劣,选用LS-DYNA的显式求解器计算国产某出口澳大利亚车型座椅安全带.通过研究改变计算时间和加载函数两项关键参数,并选取一定的评价指标,逐步提高仿真结果与实车试验的吻合度.方法可推广到其他准静态强度分析中,为提高仿真准确度提供了较好的思路.

  16. 底板设置锚筋的圆形水泵房内力分析研究和实践%Inner Force Analytic Research and Practice of the Circular Pump House to Install Anchorage on Motherboard

    Institute of Scientific and Technical Information of China (English)

    陈惠明

    2003-01-01

    在岩基和水深较大的位置修筑水泵房时,在底板设置锚筋,对泵房抗浮、改善泵房内力分布,利用自然条件降低工程造价,起到较好的作用.对底板设置锚筋的圆形水泵房进行内力分析研究,并在来宾电厂水泵房中应用,取得很好的效果.

  17. An archaeological site survey and inventory for the Aleutian Islands National Wildlife Refuge, Alaska 1972: A report submitted to the Wilderness Studies Branch, U.S. Fish and Wildlife Service, Anchorage, Alaska

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a 1972 voyage in the Aleutian archipelago to locate prehistoric and historic archeological sites. The report centers on the problems...

  18. CFRP布抗弯加固钢筋混凝土梁内锁锚固体系试验研究%Experimental Study on the Flexural Behavior of RC Beam Strengthened with CFRP Strips Inter-lock Anchorage System

    Institute of Scientific and Technical Information of China (English)

    高剑平; 温群昊; 罗丹; 罗民; 林杨

    2011-01-01

    为了充分利用CFRP材料高强的优势,抑制加固梁早期剥离破坏,本文提出一种附加锚固措施:内锁锚固系统,并进行了6根CFRP布加固钢筋混凝土梁抗弯性能试验研究,以验证这种内锁锚固系统对早期剥离破坏的抑制效果,同时研究控制参数对加固效果(破坏特征、承载力、刚度、裂缝开展等)的影响规律.试验结果表明:这种锚固方法能阻止CFRP布的剥离向端部发展,将弯剪裂缝引起的剥离限制在局部区域内,抑制其产生滑移;可提高极限荷载10% ~ 20%,提高抗弯刚度7%~34%,有效降低梁的裂缝宽度.通过对比,发现减小开槽间距对梁的受弯影响不大,适当增加开槽宽度可提高梁的抗弯刚度.%To take full advantage of high strength advantage of carbon Fiber Reinforced Plastic(CFRP) , and resolve the problem of the debonding failure of concrete beams strengthened with CERP, a new anchor system which CERP strips is proposed in this paper. Six reinforced concrete ( RC) beams strengthened with CFRP sheets are tested to evaluate the flexural behavior. The effect of anchor system on avoiding the debonding failure is validated. Furthermore, the influence of control parameters on reinforcement effect is investigated, including failure characteristics, bearing capacity, stiffness, crack developing and so on. The results show that the anchor system can prevent the debonding of CFRP from expanding to the end of CFRP due to the crack of bend and shear loads. It means the debonding of CFRP is restricted to the local area and slippage is inhibited. Besides, the ultimate load can be increased by 10% to 20% , and bending rigidity can be increased by 7% to 34% . The crack width of beams is decreased effectively. It is found that reducing the space of grooves has little influence on bearing capacity, and bending rigidity would be properly raised due to the increase of the width of grooves.

  19. 锚碇沉箱基础与升浆基床摩擦性能研究%Research on friction property between anchorage caisson foundation and grouting bed

    Institute of Scientific and Technical Information of China (English)

    耿铁锁; 陈亮; 张哲

    2015-01-01

    According to the first domestic offshore suspension bridge using caisson foundation,the friction property between prepacked aggregate riprap grouting bed and concrete under water,the friction coefficients between gravel bed and concrete structure are mainly studied.Firstly,the friction coefficients between gravel bed and concrete structure are obtained by laboratory and field experiments,and then,the friction property between prepacked aggregate riprap grouting bed and concrete structure under water is acquired by the numerical analysis method.The experimental results show that the friction coefficients between the common gravel bed and the concrete caisson are in the range of 0.5-0.6,which meets the corresponding code,and the friction coefficient between the prepacked aggregate riprap grouting bed and the concrete caisson is within 0.7-0.8,or even 0.9 considering the film cohesive force of concrete.%针对国内首个采用沉箱基础的海上悬索桥,主要对水下预填骨料抛石升浆基床与混凝土之间的摩擦性能,以及碎石基床与混凝土结构的摩擦因数展开研究.首先通过室内和现场实验得到碎石基床与混凝土结构的摩擦因数,在此基础上采用数值分析方法得到水下预填骨料抛石升浆基床与混凝土结构之间的摩擦性能.结果表明,普通碎石基床与混凝土沉箱之间的摩擦因数在设计规范规定的0.5~0.6内,而预填骨料抛石升浆基床与混凝土沉箱之间的摩擦因数为0.7~0.8,如考虑混凝土之间的黏结力膜作用,摩擦因数可达0.9.

  20. Preliminary Geologic Map of the Cook Inlet Region, Alaska-Including Parts of the Talkeetna, Talkeetna Mountains, Tyonek, Anchorage, Lake Clark, Kenai, Seward, Iliamna, Seldovia, Mount Katmai, and Afognak 1:250,000-scale Quadrangles

    Science.gov (United States)

    Geologic map compiled by Wilson, Frederic H.; Hults, Chad P.; Schmoll, Henry R.; Haeussler, Peter J.; Schmidt, Jeanine M.; Yehle, Lynn A.; Digital files prepared by Wilson, Frederic H.; Labay, Keith A.; Shew, Nora

    2009-01-01

    The growth in the use of Geographic Information Systems (GIS) has highlighted the need for digital geologic maps that have been attributed with information about age and lithology. Such maps can be conveniently used to generate derivative maps for manifold special purposes such as mineral-resource assessment, metallogenic studies, tectonic studies, and environmental research. This report is part of a series of integrated geologic map databases that cover the entire United States. Three national-scale geologic maps that portray most or all of the United States already exist; for the conterminous U.S., King and Beikman (1974a,b) compiled a map at a scale of 1:2,500,000, Beikman (1980) compiled a map for Alaska at 1:2,500,000 scale, and for the entire U.S., Reed and others (2005a,b) compiled a map at a scale of 1:5,000,000. A digital version of the King and Beikman map was published by Schruben and others (1994). Reed and Bush (2004) produced a digital version of the Reed and others (2005a) map for the conterminous U.S. The present series of maps is intended to provide the next step in increased detail. State geologic maps that range in scale from 1:100,000 to 1:1,000,000 are available for most of the country, and digital versions of these state maps are the basis of this product. The digital geologic maps presented here are in a standardized format as ARC/INFO export files and as ArcView shape files. The files named __geol contain geologic polygons and line (contact) attributes; files named __fold contain fold axes; files named __lin contain lineaments; and files named __dike contain dikes as lines. Data tables that relate the map units to detailed lithologic and age information accompany these GIS files. The map is delivered as a set 1:250,000-scale quadrangle files. To the best of our ability, these quadrangle files are edge-matched with respect to geology. When the maps are merged, the combined attribute tables can be used directly with the merged maps to make derivative maps.

  1. 正畸微种植体支抗即刻加载的稳定性研究%Histological study on immediate loading of microimplant as orthodontic anchorage in dog

    Institute of Scientific and Technical Information of China (English)

    许衍; 曾科; 景熙文; 王林; 王震东

    2008-01-01

    目的 本研究通过观察即刻加载的微种植体支抗周围骨界面组织学变化,旨在探索即刻加载是否会影响微种植体支抗的稳定性.方法 本试验选用成年狗1只,16枚正畸用微种植体植入狗的下颌骨后即刻施加1.5 N力,施力9周后狗被处死.骨标本作病理切片后进行组织学观察和测量.结果 微种植体可以承受即刻加载的1.5 N正畸力而无松动.组织学观察显示骨-微种植体界面有骨组织沉积,没有纤维组织生成,即刻加载的正畸力没有影响骨细胞在微种植体表面的沉积.结论 在严格控制植入创伤、加载力量大小的前提下,微种植体的即刻加载是可行的.

  2. Geologic map of the Cook Inlet region, Alaska, including parts of the Talkeetna, Talkeetna Mountains, Tyonek, Anchorage, Lake Clark, Kenai, Seward, Iliamna, Seldovia, Mount Katmai, and Afognak 1:250,000-scale quadrangles

    Science.gov (United States)

    Wilson, Frederic H.; Hults, Chad P.; Schmoll, Henry R.; Haeussler, Peter J.; Schmidt, Jeanine M.; Yehle, Lynn A.; Labay, Keith A.

    2012-01-01

    In 1976, L.B. Magoon, W.L. Adkinson, and R.M. Egbert published a major geologic map of the Cook Inlet region, which has served well as a compilation of existing information and a guide for future research and mapping. The map in this report updates Magoon and others (1976) and incorporates new and additional mapping and interpretation. This map is also a revision of areas of overlap with the geologic map completed for central Alaska (Wilson and others, 1998). Text from that compilation remains appropriate and is summarized here; many compromises have been made in strongly held beliefs to allow construction of this compilation. Yet our willingness to make interpretations and compromises does not allow resolution of all mapping conflicts. Nonetheless, we hope that geologists who have mapped in this region will recognize that, in incorporating their work, our regional correlations may have required some generalization or lumping of map units. Many sources were used to produce this geologic map and, in most cases, data from available maps were combined, without generalization, and new data were added where available. A preliminary version of this map was published as U.S. Geological Survey Open-File Report 2009–1108. The main differences between the versions concern revised mapping of surfical deposits in the northern and eastern parts of the map area. Minor error corrections have been made also.

  3. Certification Test of Seats and Seat Belt Anchorages of Vehicles%汽车座椅及座椅安全带固定点出口认证测试

    Institute of Scientific and Technical Information of China (English)

    覃国周

    2010-01-01

    基于重庆车辆检测研究院国家客车质量监督检验中心广泛开展的汽车出口认证检测所积累的经验,分析国外不同地区的认证检测法规与国内标准的差异,对汽车座椅及安全带固定点出口认证试验的相关内容、技术特点、常见失效形式及原因进行探讨.

  4. 基于变形加固理论的小湾拱坝坝趾锚固研究%Anchorage Design of Dam Toe of Xiaowan Arch Dam Based on Deformation Reinforcement Theory

    Institute of Scientific and Technical Information of China (English)

    杨强; 陈英儒; 周维垣

    2007-01-01

    岩体工程中加固设计的加固机理本质上是一个变形稳定问题.刚体极限平衡法不考虑变形机制,针对的是结构濒临破坏时的特定状态,其结论是有局限性的,尤其是处于高梯度应力区的坝趾,该处大坝和坝基的相互作用以及锚固实际作用都对变形极为敏感,忽略变形机制会导致很大的误差.变形加固理论要求只对出现弹塑性不平衡力的区域进行加固,且加固力和不平衡力大小相等,方向向反.同时该理论指出在给定外荷载作用条件下,真实结构总是趋于自承力最大化而加固力最小化的状态,这和潘家铮最大最小原理是一致的.运用该理论对小湾坝趾锚固及坝踵破损进行了分析.

  5. Orthodontic treatment of condylar fracture in children with implant anchorage%固定矫治器联合种植体支抗正畸治疗儿童髁突骨折

    Institute of Scientific and Technical Information of China (English)

    林有籁; 午君武; 郑松

    2013-01-01

    目的 观察正畸固定矫治器联合种植体支抗牵引固定儿童髁突骨折的治疗效果.方法 选取年龄为7~18岁,临床确诊为儿童髁突骨折的病例8例.即刻粘结正畸固定矫治器,植入种植体支抗,上颌间接支抗联合颌间牵引固定复位.结果 所有患者经治疗后均取得良好的临床疗效.张口度,咬合关系,咀嚼功能恢复正常,颌面部发育正常.全景片示髁突骨折逐渐恢复.结论 正畸固定矫治器联合种植体支抗牵引固定是临床上一种有效的治疗儿童髁突骨折的方法.

  6. The Opium Trade at Golden-star Anchorage Before and After the Opium War%鸦片战争前后金星门的鸦片贸易

    Institute of Scientific and Technical Information of China (English)

    魏雅丽

    2013-01-01

    位于广东珠江口西侧的金星门,在鸦片战争前后以其独特的地理位置和有利的条件,从19世纪20年代外国鸦片船的偶然碇泊所,发展到30年代外国鸦片船的固定碇泊所,四五十年代则成为广州市场甚至整个珠江三角洲市场鸦片的重要供应地.对金星门鸦片贸易的个案作较为深入的分析,对探讨鸦片战争前后中西关系的演变,有一定的学术价值.

  7. 33 CFR 110.72c - Lake Murray, S.C.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lake Murray, S.C. 110.72c Section 110.72c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72c Lake Murray, S.C. (a) The area beginning at the...

  8. 33 CFR 110.27 - Lynn Harbor in Broad Sound, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lynn Harbor in Broad Sound, Mass. 110.27 Section 110.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.27 Lynn Harbor in Broad Sound, Mass. North...

  9. 33 CFR 110.38 - Edgartown Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Edgartown Harbor, Mass. 110.38 Section 110.38 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.38 Edgartown Harbor, Mass. An area in the inner...

  10. 33 CFR 110.37 - Sesuit Harbor, Dennis, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sesuit Harbor, Dennis, Mass. 110.37 Section 110.37 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.37 Sesuit Harbor, Dennis, Mass. All the...

  11. 33 CFR 110.29 - Boston Inner Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Boston Inner Harbor, Mass. 110.29 Section 110.29 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.29 Boston Inner Harbor, Mass. (a) Vicinity of...

  12. 33 CFR 110.45 - Onset Bay, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Onset Bay, Mass. 110.45 Section 110.45 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.45 Onset Bay, Mass. Northerly of a line extending...

  13. 33 CFR 110.32 - Hingham Harbor, Hingham, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hingham Harbor, Hingham, Mass. 110.32 Section 110.32 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.32 Hingham Harbor, Hingham, Mass. (a) Area...

  14. 33 CFR 110.74b - Apollo Beach, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a...

  15. 33 CFR 110.73b - Indian River at Vero Beach, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Indian River at Vero Beach, Fla... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73b Indian River at Vero Beach, Fla. (a) Area A. Beginning at a point located on the eastern shore of Fritz Is. at latitude 27°39′32.5″...

  16. 33 CFR 110.129a - Apra Harbor, Guam. (Datum: WGS 84)

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. (Datum: WGS 84) 110.129a Section 110.129a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.129a Apra Harbor, Guam. (Datum: WGS 84)...

  17. 33 CFR 110.48 - Thompson Cove on east side of Pawcatuck River below Westerly, R.I.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Thompson Cove on east side of..., DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.48 Thompson... channelward end of Thompson Dock at the northern end of Thompson Cove 184° to the shore at the southern end...

  18. 33 CFR 110.70 - Chesapeake and Delaware Canal, easterly of Courthouse Point, Md.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Chesapeake and Delaware Canal, easterly of Courthouse Point, Md. 110.70 Section 110.70 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.70 Chesapeake and Delaware Canal, easterly of...

  19. 33 CFR 110.214 - Los Angeles and Long Beach harbors, California.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Los Angeles and Long Beach... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.214 Los Angeles and Long Beach... the Captain of the Port Los Angeles-Long Beach, the pilot stations for the Port of Long Beach and...

  20. 33 CFR 110.84b - Buffalo, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo, N.Y. 110.84b Section 110.84b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.84b Buffalo, N.Y. The area within the Port of Buffalo known as...

  1. 33 CFR 110.85 - Niagara River, Youngstown, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Niagara River, Youngstown, N.Y. 110.85 Section 110.85 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.85 Niagara River, Youngstown, N.Y. (a) Area...

  2. 33 CFR 110.111 - Marina del Rey Harbor, Calif.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marina del Rey Harbor, Calif. 110.111 Section 110.111 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.111 Marina del Rey Harbor, Calif. An area in the main channel within the...

  3. 33 CFR 110.196 - Sabine Pass Channel, Sabine Pass, Tex.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sabine Pass Channel, Sabine Pass, Tex. 110.196 Section 110.196 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.196 Sabine Pass Channel, Sabine Pass,...

  4. 33 CFR 110.170 - Lockwoods Folly Inlet, N.C.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lockwoods Folly Inlet, N.C. 110.170 Section 110.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.170 Lockwoods Folly Inlet, N.C. (a)...

  5. 33 CFR 110.179 - Skidaway River, Isle of Hope, Ga.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Skidaway River, Isle of Hope, Ga. 110.179 Section 110.179 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.179 Skidaway River, Isle of Hope, Ga. (a)...

  6. 33 CFR 110.83a - Cedar Point, Sandusky, Ohio.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cedar Point, Sandusky, Ohio. 110... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.83a Cedar Point, Sandusky, Ohio. The water area enclosed by the break wall beginning at latitude 41°28′13″ N., longitude 82°40′39″ W.;...

  7. 33 CFR 110.58 - Cos Cob Harbor, Greenwich, Conn.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cos Cob Harbor, Greenwich, Conn. 110.58 Section 110.58 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.58 Cos Cob Harbor, Greenwich, Conn. (a) Area...

  8. Load compensation research on twice-tension for loop anchor cable of inner lining in Yellow River-crossing tunnel

    Institute of Scientific and Technical Information of China (English)

    Yin Juan; Cao Shengrong; Qin Gan; Yang Fan

    2014-01-01

    The load compensation equipment for anchor cable named low retraction prestressed anchorage sys-tem with twice-tension (referred to as twice-tension anchorage system) is proposed in the paper. Calculation re-sults of loop anchorage prestressing loss (PL) values of inner lining(IL)in Yellow River-crossing tunnel under two anchorage systems,including twice-tension anchorage system and HM(Chinese transliteration is huan-mao)anchorage system,are introduced. The software ANSYS is selected to realize the three-dimensional (3D) finite element modeling to accomplish simulation and calculation works under the two anchorage systems,re-spectively. Stress processes of IL under the two working conditions,of which one is completed cable tensioning (CCT) and the other is water in the tunnel with the designed water pressure (DWP),are contrasted and ana-lyzed. Impacts of prestressing forces of anchor cables on structural safety under the two anchorage systems are contrasted. The calculation results show that the twice-tension anchorage system can reduce PL effectively and then increase prestresses of wall concrete(WC). Meanwhile,the anchorage system has the advantages of im-proving security and stability of tunnel structure,reducing project costs and saving steel consumption. The re-search work is available to related design and construction of anchor cable,and is worthy of promotion and ap-plication.

  9. 33 CFR 110.74a - Manatee River, Bradenton, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Manatee River, Bradenton, Fla... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74a Manatee River, Bradenton, Fla. The waters of the Manatee River enclosed by a line beginning at latitude 27°31′18.6″ N. longitude 82°36′49.2″...

  10. 33 CFR 110.74c - Bahia de San Juan, PR.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Bahia de San Juan, PR. 110.74c Section 110.74c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74c Bahia de San Juan, PR. The waters of San Antonio Channel, Bahia de San Juan, eastward...

  11. Establish the Delta Military Operations Areas Environmental Assessment Elmendorf Air Force Base, Alaska

    Science.gov (United States)

    2010-01-01

    5th Avenue, Rm. 114 Anchorage, AK 99501 Grant Hilderbrand State of Alaska Department of Fish and Game Division of Wildlife Conservation 333 Raspberry ...Game Division of Wildlife  Conservation 333  Raspberry  Rd. Anchorage AK  99515 Bob Roses Northeast Community Council 8200 E 2nd Avenue Anchorage AK...Helicopter Coordinator Boeing 737 Captain 6601 S. Airpark PI Ste. 100 Anchorage, AK 99502 Phone 907.263.3502 www.conocophillips.com We agree the

  12. 33 CFR 110.75 - Corpus Christi Bay, Tex.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Corpus Christi Bay, Tex. 110.75... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.75 Corpus Christi Bay, Tex. (a) South area. Southward of... said breakwater; and eastward of the Corpus Christi sea wall....

  13. 33 CFR 110.25 - Salem Sound, Mass.

    Science.gov (United States)

    2010-07-01

    ... described in 33 CFR 110.25(a) to the point of beginning. (f) Marblehead Harbor, Marblehead, MA. The area... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Salem Sound, Mass. 110.25 Section... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.25 Salem Sound, Mass. (a) Beverly Harbor, north of...

  14. 3 CFR - Continuation of the National Emergency Relating to Cuba and of the Emergency Authority Relating...

    Science.gov (United States)

    2010-01-01

    ... Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and Movement of Vessels... Emergency Relating to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and... north of Cuba. In July 1996 and on subsequent occasions, the Cuban government stated its intent...

  15. 33 CFR 110.72 - Blackhole Creek, Md.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Blackhole Creek, Md. 110.72... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72 Blackhole Creek, Md. The waters on the west side of Blackhole Creek, a tributary of Magothy River, southwest of a line bearing 310°30′ from the most...

  16. Enkele opmerkingen betreffende het verbeteren van effectiviteit en gebruik van autogordels. Consult aan Rijkswaterstaat te Den Haag.

    NARCIS (Netherlands)

    1973-01-01

    Remarks are presented on the efficiency and use of different types of safety belts, a possible prohibition of a special type of seat belt, the reliability of anchorage, the possible improvement of safety belts and anchorage, the presence and use of safety belts on rear seats and alternatives to prom

  17. 33 CFR 165.540 - Regulated Navigation Area; Cape Fear River, Northeast Cape Fear River, Wilmington, North Carolina.

    Science.gov (United States)

    2010-07-01

    ..., Passing Lane & Anchorage Basin, Big Island, and the Northeast Cape Fear River. Drilling or blasting is expected to occur within the Passing Lane & Anchorage Basin, Big Island, and the Northeast Cape Fear River... Lighted Buoy 27 (LL 30550/39945)). (3) Big Island. The work area includes: Part of Keg Island...

  18. Mechanical mechanism analysis of tension type anchor based on shear displacement method

    Institute of Scientific and Technical Information of China (English)

    XIAO Shu-jun; CHEN Chang-fu

    2008-01-01

    Based on the fact that the shear stress along anchorage segment is neither linearly nor uniformly distributed, the load transfer mechanism of the tension type anchor was studied and the mechanical characteristic of anchorage segment was analyzed. Shear stress-strain relationship of soil surrounding anchorage body was simplified into three-folding-lines model consisting of elastic phase, elasto-plastic phase and residual phase considering its softening eharaeteristic. Meanwhile, shear displacement method that has been extensively used in the analysis of pile foundation was introduced. Based on elasto-plastic theory, the distributions of displacement, shear stress and axial force along the anchorage segment of tension type anchor were obtained, and the formula for calculating the elastic limit load was also developed accordingly. Finally, an example was given to discuss the variation of stress and displacement in the anchorage segment with the loads exerted on the anchor, and a program was worked out to calculate the anchor maximum bearing capacity. The influence of some parameters on the anchor bearing capacity was discussed, and effective anchorage length was obtained simultaneously. The results show that the shear stress first increases and then decreases and finally trends to theresidual strength with increase of distance from bottom of the anchorage body, the displacement increases all the time with theincrease of distance from bottom of the anchorage body, and the increase of velocity gradually becomes greater.

  19. 33 CFR 110.91 - Mission Bay, Calif.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.91 Mission Bay, Calif. (a) Area M-1. In San Juan Cove... San Diego Park and Recreation Department pursuant to local ordinances. (b) Area M-2. In Santa Barbara... the placing of temporary moorings in this area is exercised by the City of San Diego Park...

  20. Calculation of shear strength of prestressed hollow core slabs by use of plastic theory

    DEFF Research Database (Denmark)

    Hoang, Linh Cao; Jørgensen, Henrik Brøner; Nielsen, Mogens Peter

    2014-01-01

    saw-cut into units with the desirable length. For this reason, hollow core slabs are usually not shear reinforced and anchorage of the prestressing strands has to be established by bond. Hollow core slabs may therefore be more critical to shear and Anchorage failure than ordinary two-way spanning...... reinforced concrete slabs....

  1. Calculation of shear strength of prestressed hollow core slabs by use of plastic theory

    DEFF Research Database (Denmark)

    Hoang, Linh Cao; Jørgensen, H.G.; Nielsen, Mogens Peter

    2014-01-01

    saw-cut into units with the desirable length. For this reason, hollow core slabs are usually not shear reinforced and anchorage of the prestressing strands has to be established by bond. Hollow core slabs may therefore be more critical to shear and anchorage failure than ordinary two-way spanning...... reinforced concrete slabs....

  2. 转矩作用对微植体矫治力系内收上前牙影响的三维有限元研究%Three dimensional finite element analysis of the maxillary anterior teeth retraction under torque with micro-implant anchorage system

    Institute of Scientific and Technical Information of China (English)

    张磊; 樊瑜波

    2007-01-01

    目的 研究转矩力的作用对于微植体矫治力系内收上前牙的影响.方法 利用MIMICS软件和有限元软件ABAQUS,建立微植体矫治力系的有限元模型,并在该模型上计算分析有无转矩及转矩作用区域对中切牙和侧切牙移动趋势的影响.结果 不加转矩时,中切牙和侧切牙都表现出舌向倾斜的趋势.在100 g·cm转矩力的作用下,随着转矩作用区域的增大,中切牙的唇向移动趋势逐渐减小,侧切牙由舌向移动逐渐转为唇向移动.结论 转矩能够有效改变牙齿的移动方式,如果转矩从中切牙之间开始向两侧远中方向逐渐减少,效果会更好.

  3. Safe region of micro-implant used for orthodontic anchorage positioning in the posterior maxillary alveolar bone%上颌后牙区正畸微种植体支抗植入安全区的测量研究

    Institute of Scientific and Technical Information of China (English)

    赵静子; 张文君; 张晓东

    2015-01-01

     Objective   This study aimed to measure the distance between a tooth and a soft tissue. This study also aimed to determine the safe region of micro-implant for orthodontic anchorage positioning in the posterior maxillary alveolar bone. Methods   Twenty-one cone beam computed tomography reconstruction images of the craniofacial bone of pre-orthodontic patients were used in this research. Both sides of the mesiodistal distance of the two adjacent teeth in the posterior maxillary alveolar bone were measured at 6, 8, 10, 12, 14, and 16 mm from the horizontal plane. A vernier caliper was used to measure the clinical crown height of the posterior maxillary teeth in the plaster maxillary dentition model. A periodontal probe along the long axis of a tooth was used to determine the width of the free gingiva and the width from the gingival margin to the mucogingival junction. Results  In the posterior area of the maxilla, the widest mesiodistal distance of tooth roots was between the second premolar and the first molar. Among the teeth, the maxillary first premolar yielded the highest crown height. The maxillary second molar region showed the widest attached gingiva. Conclusion  The safe region of the micro-implant is located in the second premolar and the first molar; the vertical distance from the horizontal plane is 10-11 mm.%目的:通过测量与正畸微种植体植入相关的牙体距离和软组织距离,确定上颌后牙区正畸微种植体支抗植入的安全区。方法采用21例正畸前患者颅面部锥形束CT扫描重建图像,使用测量软件测量上颌左右两侧后牙区距水平面6、8、10、12、14、16 mm处相邻两牙牙根的近远中距离,游标卡尺测量双侧上颌后牙临床牙冠的高度,牙周探针测量双侧上颌后牙区附着龈的宽度。结果上颌第二前磨牙和第一磨牙近中颊根之间的近远中距离最大,上颌第一前磨牙的牙冠高度最大,上颌第二磨牙的附着龈宽度最大。结论上颌后牙处微种植体植入的安全区位于上颌第二前磨牙与第一磨牙之间,距相邻两牙颊尖连线垂直高度10~11 mm处。

  4. 采用异体腘绳肌腱Rigidfix交叉钉与Intrafix膨胀挤压螺钉重建前交叉韧带初步报道%ANTERIOR CRUCIAL LIGAMENT RECONSTRUCTION WITH ALLOGRAFT HAMSTRING FIXED BY RIGIDFIX AND INTRAFIX ANCHORAGES

    Institute of Scientific and Technical Information of China (English)

    白伦浩; 王佳时; 傅永慧; 付勤

    2007-01-01

    目的 探讨关节镜下采用可吸收Rigidfix交叉钉与Intrafix 膨胀挤压螺钉固定异体腘绳肌腱移植、重建膝关节前交叉韧带(anterior cruciate ligament, ACL)的手术方法和近期疗效.方法 2006年1月~12月,取低温冷冻异体腘绳肌腱作为ACL的替代物,关节镜下应用可吸收Rigidfix交叉钉与Intrafix 膨胀挤压螺钉固定治疗ACL损伤21例.其中男13例,女8例;年龄18~53岁.损伤原因:交通伤7伤,运动损伤11例,其他原因3例.合并Ⅱ度内侧副韧带(medial collateral ligament, MCL)及半月板损伤10例,内外侧半月板同时损伤3例,外侧半月板损伤6例,单纯ACL损伤2例.受伤至手术时间为7 d~3个月.手术前、后按照Lysholm膝关节评分标准进行评价. 结果 术后21例均获3~9个月随访,平均5.8个月.术后膝关节活动范围19例超过120°;1例合并MCL损伤术后3个月屈膝受限80°,二期行关节镜下松解术;1例因排斥反应关节肿胀、发热,行关节镜冲洗后缓解.术后21例前抽屉试验、轴移试验均阴性,Lanchman试验Ⅰ度阳性1例,其余为阴性.Lysholm评分从术前56.73±6.58分增加至术后88.14±7.02分,差异有统计学意义(P<0.01). 结论 关节镜下采用可吸收Rigidfix交叉钉与Intrafix 膨胀挤压螺钉固定异体腘绳肌腱重建膝关节ACL,手术方法简便,固定确实可靠,患者创伤小;术后早期康复锻炼,能快速恢复功能.

  5. Influência da expansão rápida da maxila na rizólise dos caninos decíduos usados como ancoragem Influence of rapid maxillary expansion on the root resorption of primary canines used as anchorage

    Directory of Open Access Journals (Sweden)

    Omar Gabriel da Silva Filho

    2009-10-01

    Full Text Available OBJETIVOS: o presente estudo radiográfico, retrospectivo e longitudinal objetivou determinar se a ancoragem do aparelho expansor fixo tipo Haas, modificado para as dentaduras decídua e mista, interfere na velocidade de rizólise e esfoliação dos caninos decíduos. MÉTODOS: foi feita uma avaliação quantitativa da rizólise do canino decíduo mediante a medição do comprimento coroa-ápice dos caninos decíduos superiores, dos lados direito e esquerdo. Para essa avaliação, 24 crianças submetidas à expansão rápida da maxila (ERM na dentadura decídua ou no início da dentadura mista foram comparadas com 15 crianças que não passaram por esse procedimento. A medição do comprimento coroa-ápice dos caninos decíduos foi realizada com o programa computadorizado CEF-X Cefalometria Digital, produzido pela CDT Informática, que permitiu calibrar o tamanho dos dentes pela uniformização das imagens radiográficas digitalizadas. RESULTADOS: os dados estatísticos revelaram que não houve diferença na velocidade de rizólise dos caninos decíduos entre as crianças do grupo controle e as do grupo submetido à ERM. CONCLUSÕES: é possível inferir que o aparelho expansor fixo tipo Haas ancorado em dentes decíduos não influencia a rizólise dos caninos decíduos usados como ancoragem.AIM: The current radiographic, retrospective longitudinal study aim was to demonstrate whether the Haas fixed appliance, modified for the primary and mixed dentitions, interferes in the velocity of the root resorption and exfoliation of the primary canines. METHODS: It was evaluated the amount of root resorption of primary canines on the basis of measurements of the apex-crown length of right and left upper primary canines. For this measurement twenty-four children submitted to rapid maxillary expansion (RME in the primary and mixed dentition were compared to 15 children who did not undergo such a procedure. The measurement of the apex-crown length of the primary canines was achieved with the CEF-X program that allowed the calibration and standardization of the image size. RESULTS: Statistical data revealed that no difference was found in the velocity of root resorption of the primary canines between the control and experimental groups. CONCLUSIONS: The findings of this study allow us to conclude that root resorption of primary canines has no relationship with RME.

  6. Bone anchor systems for orthodontic application: a systematic review.

    Science.gov (United States)

    Tsui, W K; Chua, H D P; Cheung, L K

    2012-11-01

    This systematic review was performed to investigate the usefulness and clinical effectiveness of skeletal anchorage devices to determine the most effective bone anchor system for orthodontic tooth movement. Literature on bone anchorage devices was selected from PubMed and the Cochrane Library from January 1966 to June 2010. 55 publications regarding miniplates, miniscrews, palatal implants and dental implants as orthodontic anchorage were identified for further analysis. All bone anchorage devices were found to have relatively high success rates and demonstrated their ability to provide absolute anchorage for orthodontic tooth movement. Significant tooth movement could be achieved with low morbidities and good patient acceptance. The reported success rates for the four groups of anchorage systems were generally high with slight variability (miniplates 91.4-100%; palatal implants 74-93.3%; miniscrews 61-100%; dental implants 100%). It was concluded that bone anchorage systems can achieve effective orthodontic movement with low morbidities. The success rate is generally high with slight variability between miniplates, palatal implants, miniscrews and dental implants. Owing to the lack of randomized controlled trials, there is no strong evidence to confirm which bone anchor system is the most effective for orthodontic tooth movement.

  7. ARCTIC FOUNDATIONS, INC. FREEZE BARRIER TECHNOLOGY; INNOVATIVE TECHNOLOGY EVALUATION REPORT

    Science.gov (United States)

    Arctic Foundations, Inc. (AFI), of Anchorage, Alaska has developed a freeze barrier technology designed to prevent the migration of contaminants in groundwater by completely isolating contaminant source areas until appropriate remediation techniques can be applied. With this tech...

  8. ARCTIC FOUNDATIONS, INC. FREEZE BARRIER SYSTEM - SITE TECHNOLOGY CAPSULE

    Science.gov (United States)

    Arctic Foundations, Inc. (AFI), of Anchorage, Alaska has developed a freeze barrier technology designed to prevent the migration of contaminants in groundwater by completely isolating contaminant source areas until appropriate remediation techniques can be applied. With this tec...

  9. Proposed Becharof Wildlife Refuge headquarters site inventory King Salmon and Naknek

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — As (d)(2) legislation moves through Congress, the Refuges and Resource Planning Divisions of the U.S. Fish and Wildlife Service office in Anchorage work to prepare...

  10. Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

    DEFF Research Database (Denmark)

    Hong, Xin; Nguyen, Thanh Hung; Chen, Qingfeng;

    2014-01-01

    Cancer genomes accumulate numerous genetic and epigenetic modifications. Yet, human cellular transformation can be accomplished by a few genetically defined elements. These elements activate key pathways required to support replicative immortality and anchorage independent growth, a predictor of ...

  11. Miniscrew implant applications in contemporary orthodontics.

    Science.gov (United States)

    Chang, Hong-Po; Tseng, Yu-Chuan

    2014-03-01

    The need for orthodontic treatment modalities that provide maximal anchorage control but with minimal patient compliance requirements has led to the development of implant-assisted orthodontics and dentofacial orthopedics. Skeletal anchorage with miniscrew implants has no patient compliance requirements and has been widely incorporated in orthodontic practice. Miniscrew implants are now routinely used as anchorage devices in orthodontic treatment. This review summarizes recent data regarding the interpretation of bone data (i.e., bone quantity and quality) obtained by preoperative diagnostic computed tomography (CT) or by cone-beam computed tomography (CBCT) prior to miniscrew implant placement. Such data are essential when selecting appropriate sites for miniscrew implant placement. Bone characteristics that are indications and contraindications for treatment with miniscrew implants are discussed. Additionally, bicortical orthodontic skeletal anchorage, risks associated with miniscrew implant failure, and miniscrew implants for nonsurgical correction of occlusal cant or vertical excess are reviewed. Finally, implant stability is compared between titanium alloy and stainless steel miniscrew implants.

  12. ATLAS Civil Engineering Point 1

    CERN Multimedia

    2001-01-01

    Different phases of realisation to Point 1: zone of the ATLAS experiment 14-02-2001Realising anchorage, isolations and scaffoldings at UX 15 18-04-2001Concreting the arch and posing the metal reinforcements at UX 15

  13. 33 CFR 110.205 - Chicago Harbor, Ill.

    Science.gov (United States)

    2010-07-01

    ... ground for the common convenience, or for otherwise enforcing this section, shall be promptly executed by... stakes in anchorages A and B. (Mooring facilities are available adjacent to the lakeside guidewalls...

  14. 76 FR 5395 - Alaska Native Claims Selection

    Science.gov (United States)

    2011-01-31

    ...-877-8339, 24 hours a day, 7 days a week. Dina L. Torres, Land Transfer Resolution Specialist, Branch... aggregate 86.80 acres. Notice of the decision will also be published four times in the Anchorage Daily...

  15. 76 FR 60806 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2011-09-30

    ... physically accessible to people with disabilities. Requests for sign language interpretation or other... will be held at the Clarion Suites, Heritage Room, 1110 West 8th Avenue, Anchorage AK. Council...

  16. Torque Loss in En-Masse Retraction of Maxillary Anterior Teeth Using Miniimplants with Force Vectors at Different Levels: 3D FEM Study

    OpenAIRE

    Parashar, Abhishek; Aileni, Kaladhar Reddy; Rachala, Madhukar Reddy; Shashidhar, Nagam Reddy; Mallikarjun, Vankre; Parik, Nupur

    2014-01-01

    Objective: This FEM study was conducted to quantify the amount of torque loss in maxillary anterior teeth by applying force vectors from different levels to the anterior retraction hook at various heights and comparing with that of molar anchorage system.

  17. 8 CFR 100.4 - Field offices.

    Science.gov (United States)

    2010-01-01

    ... May, Deepwater Point, Fisher's Point, Gibbstown, Gloucester City, Paulsboro, Salem, and Trenton, NJ... facilities at Beaver, Columbia City, Prescott, Rainier, and St. Helens, OR) District No. 32—Anchorage,...

  18. 76 FR 6841 - Notice of Receipt of Petition for Decision That Nonconforming 2006 and 2007 Aston Martin Vantage...

    Science.gov (United States)

    2011-02-08

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary... Zone Intrusion, 225 Child Restraint Anchorage Systems, 302 Flammability of Interior Materials, and...

  19. 76 FR 69796 - Notice of Receipt of Petition for Decision That Nonconforming 2002 Jaguar XJ8 Passenger Cars...

    Science.gov (United States)

    2011-11-09

    ... greater than 15 pages in length, although there is no limit to the length of necessary attachments to the..., 225 Child Restraint Anchorage Systems, 301 Fuel System Integrity, 302 Flammability of...

  20. 77 FR 70541 - Notice of Receipt of Petition for Decision That Nonconforming 2009 Porsche 911 (997) Passenger...

    Science.gov (United States)

    2012-11-26

    ... greater than 15 pages in length, although there is no limit to the length of necessary attachments to the... Resistance, 219 Windshield Zone Intrusion, 225 Child Restraint Anchorage Systems, and 302 Flammability...

  1. 77 FR 67732 - Notice of Receipt of Petition for Decision That Nonconforming 2009 Porsche Cayenne S Multipurpose...

    Science.gov (United States)

    2012-11-13

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary... Resistance, 219 Windshield Zone Intrusion, 225 Child Restraint Anchorage Systems, and 302 Flammability...

  2. 76 FR 49834 - Notice of Receipt of Petition for Decision That Nonconforming 2009 Dodge RAM 1500 Laramie Crew...

    Science.gov (United States)

    2011-08-11

    ... greater than 15 pages in length, although there is no limit to the length of necessary attachments to the... Intrusion, 225 Child Restraint Anchorage Systems, 301 Fuel System Integrity, and 302 Flammability...

  3. 14 CFR 93.51 - Applicability.

    Science.gov (United States)

    2010-01-01

    ... AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area § 93.51... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Applicability. 93.51 Section 93.51..., Terminal Area....

  4. 76 FR 70156 - Draft Programmatic Environmental Impact Study (PEIS) for Proposed 5-Year Outer Continental Shelf...

    Science.gov (United States)

    2011-11-10

    ... Renaissance Mobile Riverview Plaza Hotel, 64 South Water Street, Mobile, AL 36602; and December 8, 2011, New... the Wilda Marston Theatre, 3600 Denali Street, Anchorage, AK; December 12, 2011, Kotzebue at the...

  5. 78 FR 46596 - Secretarial Commission on Indian Trust Administration and Reform

    Science.gov (United States)

    2013-08-01

    ..., 2013, to: trustcommission@ios.doi.gov to ensure adequate meeting packets will be made available.... 6th Avenue, Anchorage, Alaska 99501. We encourage you to RSVP to trustcommission@ios.doi.gov by...

  6. Eagle river flats bird dieoff: A summary of findings 1988

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Since 1982, periodic waterfowl die-offs have been documented at Ft. Richardson Army Base, Anchorage, Alaska in an area at the mouth of Eagle River known as Eagle...

  7. 9 CFR 93.107 - Special provisions.

    Science.gov (United States)

    2010-01-01

    ... following ports of entry: Anchorage, AK; Fairbanks, AK; Los Angeles, CA; San Diego, CA; Denver, CO; Miami...; Pembina, ND; Portal, ND; Portland, OR; San Juan, PR; Houston, TX; Highgate Springs, VT; Seattle, WA;...

  8. 33 CFR 110.193a - St. Joseph Bay, Fla.

    Science.gov (United States)

    2010-07-01

    ...′30″, 3,100 yards southeast of FW South Channel Light and 5,250 yards south of FW North Channel Light... northeast of the north entrance channel to Port St. Joe, Florida. (2) Explosives Anchorage Area 2....

  9. 24 CFR 3286.505 - Minimum elements to be inspected.

    Science.gov (United States)

    2010-04-01

    ... with respect to home design and construction; (b) Consideration of site-specific conditions; (c) Site preparation and grading for drainage; (d) Foundation construction; (e) Anchorage; (f) Installation of...

  10. 78 FR 13395 - Federal Aviation Administration

    Science.gov (United States)

    2013-02-27

    ... Federal Aviation Administration Notice of Availability of Draft Alaska National Interest Lands Conservation Act (ANILCA) Section 810 Subsistence Evaluation. AGENCY: Federal Aviation Administration (FAA... Aviation Administration, Airports Division, 222 West 7th Avenue, Box 14, Anchorage, AK 99513. 5....

  11. Modified Dento - Alveolar Distraction Osteogenesis Technique for Rapid Canine Retraction

    Directory of Open Access Journals (Sweden)

    Sameer Patil

    2012-01-01

    Full Text Available Distraction Osteogenesis claims to reduce the duration of treatment as well aid in conservation of anchorage. With the introduction of Dento- alveolar distraction retraction of canine can now be done in about 2-3 weeks with minimal loss of anchorage and little/no root resorption. However, surgical procedure required for dento-alveolar distraction can cause significant swelling and post operative discomfort. Our small modification in the surgical procedure drastically reduces the discomfort and improves patient compliance.

  12. Modified Dento - Alveolar Distraction Osteogenesis Technique for Rapid Canine Retraction

    OpenAIRE

    Sameer Patil; Sharadindu Kotrashetti; Sumit Yadev; Ketan Vhora

    2012-01-01

    Distraction Osteogenesis claims to reduce the duration of treatment as well aid in conservation of anchorage. With the introduction of Dento- alveolar distraction retraction of canine can now be done in about 2-3 weeks with minimal loss of anchorage and little/no root resorption. However, surgical procedure required for dento-alveolar distraction can cause significant swelling and post operative discomfort. Our small modification in the surgical procedure drastically reduces the discomfort an...

  13. Acoustic Nondestructive Testing and Measurement of Tension for Steel Reinforcing Members: Part 2 - Field Testing

    Science.gov (United States)

    2014-09-01

    steel beam-and-girder designs, but a significant problem is that the anchor tendons (i.e., rods) are inaccessible for expedient inspection and repair . A...embedded in concrete. Acoustic waves are nondestructive. They can travel long distances through engineered structures and can be used to thoroughly...complete post-tensioned anchorage system includes tendons (bars/rods or strands), anchorage devices or bearing plates, ducts, end caps, grout tubes

  14. Analysis of Radiation Exposure for Naval Personnel at Operation SANDSTONE.

    Science.gov (United States)

    1983-08-15

    Operation SANDSTONE Dose Reconstruction Methodology I I 2-1 Enewetak Atoll Anchorage Areas 14 2-2 Destroyer Patrol Sector Chart for Operation SANDSTONE 18...2-3 Average Free-Field Radiation Intensity for Southern and Northern Anchorage Areas - Enewetak Atoll 24 2-4 Average Free-Field Radiation Intensity...Operation SANDSTONE was the second nuclear test series held in the Marshall 0 Islands. It consisted of three nuclear weapon tests at Enewetak * Atoll in

  15. Orthodontic anchoring techniques and its influence on pain, discomfort, and jaw function--a randomized controlled trial.

    Science.gov (United States)

    Feldmann, Ingalill; List, Thomas; Bondemark, Lars

    2012-02-01

    The aim of this trial was to evaluate and compare perceived pain, discomfort, and jaw function impairment between orthodontic treatments combined with skeletal anchorage and treatment using conventional anchorage with headgear or transpalatal bar. A total of 120 adolescent patients in order to start orthodontic treatment were consecutively recruited and randomized into three groups with different anchorage. Group A underwent installation of a skeletal anchorage (Onplant or Orthosystem implant), group B received headgear, and group C a transpalatal bar. Questionnaires were used to assess pain intensity, discomfort, analgesic consumption, and jaw function impairment from baseline to the end of treatment. Pain scores overall peaked on day 2 and were almost back to baseline on day 7. The site with the highest pain scores during treatment was incisors in contact but with no differences between groups. Pain intensity from molars was significantly less in the skeletal anchorage group A compared to the transpalatal bar group C the first 4 days in treatment and with no sign differences compared to headgear. The results confirm that there were very few significant differences between patients' perceptions of skeletal and conventional anchorage systems during orthodontic treatment. Consequently, these new appliances were well accepted by the patients in a long time perspective and can thus be recommended.

  16. Application of pre-stressed technology in the crossing construction of the China–Myanmar Gas Pipeline

    Directory of Open Access Journals (Sweden)

    Xuejun Wang

    2015-01-01

    Full Text Available Concrete structure is commonly used in the anchorages of a large cable-suspended pipeline crossing construction. With the increase of span and load, the stress on the concrete anchorages may rise rapidly. In case of traditional anchoring structure fixed by anchor rods, concrete cracking will occur, thereby reducing the anchorage life. To solve this problem, the pre-stressed structure was designed to effectively improve the efficiency of anchoring and reduce engineering cost. In the crossing construction of China–Myanmar Gas Pipeline, the pre-stressed technology was used to establish an effective pre-stressed anchoring system, which integrates the pre-stressed structures (e.g. tunnel anchorages in the anchors and the optimization measures (e.g. positioning mode, anchorage structure, concrete placement, pre-stressed, and medium injection, in line with the crossing structure and load features of this project. The system can delay the occurrence of concrete cracking and enhance the stress durability of the structure and anchoring efficiency. This technology has been successfully applied in the crossing construction of China–Myanmar Gas Pipeline, with good economic and social benefits, indicating that this technology is a new effective solution to the optimization of suspended pipeline anchorage structures, providing technical support for the development of pipeline crossing structure.

  17. Analisis parametrico de las variables que influyen en el comportamiento adherente de las armaduras pretesas en el hormigon

    Science.gov (United States)

    Arbelaez Jaramillo, Cesar Augusto

    Prestressed concrete technique through the use of prestressed reinforcement is extended in the precast concrete industry. This technique consists on casting a concrete element over a previously prestressed reinforcement, proceeding to release once the concrete has reached a determined strength so the prestressed stress introduced to the reinforcement be transmitted, by bond, to concrete. The bond behaviour of prestressed reinforcement includes two phenomena: prestress transmission from the reinforcement to concrete and anchorage of the reinforcement. This bond behaviour is characterized by mean of two lengths: transmission length and anchorage length. The good design of these lengths is a basic and fundamental aspect in the project of precast prestressed concrete elements to guaranty the appropriate transmission of prestress and to allow the anchorage of the reinforcement along the structural element service life. The influence of the parameters related to the concrete dosage on the transmission and anchorage lengths of prestressing strands have been analyzed. The ECADA test method has been applied. With this method the operations of transmission of prestress and anchorage of the reinforcement are sequentially done. The transmission and anchorage lengths are determined from the force control supported by the reinforcement testing series of specimens with different embedment lengths. The differentiation of the concepts of anchorage length without slips and with slips has been proposed. The relationship of the parameters of dosage with the bond stress and the registered slips during the processes of transmission and anchorage has been studied. Expressions to value the slips distribution of the reinforcement in the transmission zone and in the anchorage zone have been proposed. A study on the determination of the transmission length from the free reinforcement slip end has been done and the viability to experimentally determine the transmission length from the slips

  18. An analysis of the tensile type anchor system interface characteristic rheological experiments under constant load%恒定荷载下拉力型锚杆系统界面流变实验特性分析

    Institute of Scientific and Technical Information of China (English)

    徐晓阳; 马露; 高文华

    2016-01-01

    More and more attention has been paid to the anchorage system rheology in geotechnical anchoring.Researches have been made for anchoring the mechanical properties of interface,and theory and tests of the anchoring interface shear stress distribution are obtained.But the rheology of anchorage interface of anchorage system is seldom examined to be a balanced stress influence.Based on the modified experimental device and system,in view of the anchoring interface rheology in anchorage,the interface rheological test is carried out and the anchorage system interface of rheological properties and rheological state standard are obtained.The results are of great realistic significance to adding the anchor rock mass stability control.%针对已经达到应力平衡的锚固系统开展锚固界面流变试验,验证了锚杆系统的4种破坏形式.锚固系统界面的流变过程主要经历初始、稳定和加速流变3个阶段,通过流变速率曲线可直接判定锚杆系统的界面流变状态.

  19. Mia-assisted orthodontic treatment for dental malocclusion secondary to periodontal disease.

    Science.gov (United States)

    Feng, Yi-miao; Fang, Bing; Xia, Yun hui; Shu, Rong; Hans, Mark Guenther

    2009-01-01

    In contemporary dental care, an increasing number of adult patients with periodontal disease are seeking orthodontic treatment. Achieving optimal results in such adult patients is difficult because decreased posterior tooth anchorage is risky. This case report demonstrates the use of miniscrew implant anchorage (MIA) in a Chinese male 21 years 5 months of age with maxillary and mandibular anterior dental spacing, bimaxillary protrusion, and severe bone loss caused by periodontal disease. Prior to orthodontic treatment, the patient underwent treatment to control his periodontitis. The patient was treated with 0.022-in straight-wire orthodontic appliances. After 17 months of active orthodontic treatment, the patient had healthier periodontal tissue with increased bone support, as well as improved facial esthetics and a functional occlusion. The results demonstrate that MIA is useful in enhancing anchorage in patients with bone loss associated with severe periodontal disease.

  20. Computing of the Anchor by the Method of Three-Dimension Point-Radiate Infinite Elements

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    On the basis of the one-dimension infinite element theory, the coordinate translation and shape function of 3D point-radiate 8-node and 4-node infinite elements are derived. They are coupled with 20-node and 8-node finite elements to compute the compression distortion of the prestressed anchorage segment. The results indicate that when the prestressed force acts on the anchorage head and segment, the stresses and the displacements in the rock around the anchorage head and segment concentrate on the zone center with the anchor axis, and they decrease with exponential forms. Therefore,the stresses and the displacement spindles are formed. The calculating results of the infinite element are close to the theoretical results. This indicates the method is right. This article introduces a new way to study the mechanism of prestressed anchors. The obtained results have an important role in the research of the anchor mechanism and engineering application.

  1. Versatile retraction mechanics: Implant assisted en-masse retraction with a boot loop

    Directory of Open Access Journals (Sweden)

    Pramod Philip

    2015-01-01

    Full Text Available The purpose of this paper is to explain the versatility offered by the use of arch wires with boot loops in retraction mechanics while taking direct anchorage from mini-screws. Materials and Methods: The materials include the mini screws placed at the appropriate location and retraction arches made of 0.019 X 0.025 SS with boot loops placed distal to the lateral incisors. Mini screw provides a stable anchorage for enmasse retraction of the anterior teeth with the help of a boot loop using sliding and/or loop mechanics. Results: The arch wires with boot loops have a definite advantage over the soldered/ crimpable hooks because of the versatility it offers during the process of retraction. Conclusion: An innovative approach combining the advantages of absolute anchorage using mini implants and a retraction arch with boot loop is presented here.

  2. Orthodontic Implants: Concepts for the Orthodontic Practitioner

    Science.gov (United States)

    Elias, Carlos Nelson; de Oliveira Ruellas, Antônio Carlos; Fernandes, Daniel Jogaib

    2012-01-01

    Orthodontic implants have become a reliable method in orthodontic practice for providing temporary additional anchorage. These devices are useful to control skeletal anchorage in less compliant patients or in cases where absolute anchorage is necessary. There are a great number of advantages in this new approach which include easy insertion, decreased patient discomfort, low price, immediate loading, reduced diameter, versatility in the forces to be used, ease of cleaning, and ease of removal. However, a proper management of the screws by the practitioner is necessary in order to increase the success rate of the technique. The purpose of this paper is to update practitioners on the current concepts of orthodontic implants and orthodontic mechanics. PMID:23209470

  3. Stone cladding engineering

    CERN Document Server

    Sousa Camposinhos, Rui de

    2014-01-01

    This volume presents new methodologies for the design of dimension stone based on the concepts of structural design while preserving the excellence of stonemasonry practice in façade engineering. Straightforward formulae are provided for computing action on cladding, with special emphasis on the effect of seismic forces, including an extensive general methodology applied to non-structural elements. Based on the Load and Resistance Factor Design Format (LRDF), minimum slab thickness formulae are presented that take into consideration stress concentrations analysis based on the Finite Element Method (FEM) for the most commonly used modern anchorage systems. Calculation examples allow designers to solve several anchorage engineering problems in a detailed and objective manner, underlining the key parameters. The design of the anchorage metal parts, either in stainless steel or aluminum, is also presented.

  4. Surgically assisted rapid palatal expansion with tent screws and a custom-made palatal expander: a case report.

    Science.gov (United States)

    Park, Kang-Nam; Lee, Chang Youn; Park, In Young; Kim, Jwa Young; Yang, Byoungeun

    2015-12-01

    Rapid palatal expansion(RPE) with the tooth-born appliance is not sufficient to apply to the patients with periodontal problem or insufficient tooth anchorage, and it leads to tipping of the anchorage teeth and increasing teeth mobility and root resorption. To avoid these disadvantages, we present the case using palatal screws and custommade palatal expander. A 23-year-old patient underwent surgically assisted rapid maxillary expansion with the Hyrax expansion using 4 tent screws. The study models were used to measure the pre-/-post surgical width of the anterior and posterior dental arches with a digital sliding caliper. In the result, the custom-made palatal expander with 4 tent screws is suitable for delivering a force to the mid-palatal suture expansion. And it is low cost, small sized and simply applied. The results indicated that maxillary expansion with the custom-made palatal anchorage device is predictable and stable technique without significant complications in patients.

  5. A Mini-review on the Effect of Mini-implants on Contemporary Orthodontic Science.

    Science.gov (United States)

    Nosouhian, Saeid; Rismanchian, Mansour; Sabzian, Roya; Shadmehr, Elham; Badrian, Hamid; Davoudi, Amin

    2015-01-01

    The purpose of this literature review was to screen the valuable published articles regarding to the impacts of mini-implants on orthodontic science, briefly. The searching category was performed on the Pubmed using MeSH words such as "dental (mini) implants, orthodontic anchorage procedures, and orthodontic appliances." After preliminary sketch, they were grouped as follow: Those evaluating (a) common appliances for providing orthodontic anchorage, (b) biomechanical details of mini-implants and their insertion, (c) clinical application of mini-implants for orthognathic treatments, (d) limitations and possible complications. In conclusion, mini-implant evolved the orthodontic treatment plans and compromised the required orthognathic surgery. Malocclusion treatment and pure orthodontic or orthopedic movements in the three-dimensions have become recently possible by using mini-implant to provide skeletal anchorage.

  6. Orthodontic Implants: Concepts for the Orthodontic Practitioner

    Directory of Open Access Journals (Sweden)

    Carlos Nelson Elias

    2012-01-01

    Full Text Available Orthodontic implants have become a reliable method in orthodontic practice for providing temporary additional anchorage. These devices are useful to control skeletal anchorage in less compliant patients or in cases where absolute anchorage is necessary. There are a great number of advantages in this new approach which include easy insertion, decreased patient discomfort, low price, immediate loading, reduced diameter, versatility in the forces to be used, ease of cleaning, and ease of removal. However, a proper management of the screws by the practitioner is necessary in order to increase the success rate of the technique. The purpose of this paper is to update practitioners on the current concepts of orthodontic implants and orthodontic mechanics.

  7. 碳纤维加固钢筋混凝土抗弯构件抗剥离试验研究%Study on Basic Problems of RC Flexural Member Strengthened with CFRP

    Institute of Scientific and Technical Information of China (English)

    李友彬

    2012-01-01

    RC beams Strengthened with CFRP is used widely in civil engineering world. Strengthened with the carbon fiber, the bearing capacity in the cross-section of reinforced concrete beams and slabs has been greatly improved. Affections of the carbon fiber layers are the most obvious and tremendous of all, the more, the better. However, this growth is not linear. Compared to U-Anchorage and non-Anchorage, X Anchorage is much better. The experiment has been carried on with 11 simple rectangular cross-section beams with the same size, the same steel rate except that 3 ones with only 1 layer of the carbon fiber. During the experiment, different layers of carbon fiber has been fixed to these structures, the strengthening effect of the U-Anchorage, X-Anchorage and non-Anchorage has been compared.%碳纤维增强塑料(CFRP)加固修复混凝土结构在工程中的应用极为广泛,能有效提高钢筋混凝土构件的承载力以及变形能力,但提高只能在一定范围有效,采取锚固措施更能提高效果,X型箍锚固效果优于U型箍.试验采用11根通过粘贴不同层数的碳纤维布进行加固,同时比较U型锚固与X型锚固及无锚固三种情况下的加固效果.

  8. Establish the Delta Military Operations Area Environmental Assessment

    Science.gov (United States)

    2010-01-01

    threats to pi lots in the training airspace. Warning Area. Military training airspace off the U.S. coast. Warning Areas serve to alert non...Department of Fish and Game Division of Wildlife Conservation 333 Raspberry Rd. Anchorage, AK 99515 Jim Freechione State of Alaska Department of...Hilderbrand State of Alaska Department of Fish and Game Division of Wildlife  Conservation 333  Raspberry  Rd. Anchorage AK  99515 Bob Roses Northeast

  9. Topographic features around Zhongshan Station, southeast of Prydz Bay

    Institute of Scientific and Technical Information of China (English)

    FENG Shouzhen; XUE Zuo; CHI Wanqing

    2008-01-01

    Considering the complex topographic features of the southeast of Prydz Bay where China's Zhongshan Station is located, three types of geomorphologic units can be identified, i.e., submarine slopes, canyons, and terrains. The major topographic features in the study area are the submarine canyon and trough system outside the calving ice front of Dalk Glacier. A 3.8 km × 80 m fissure is found on the submarine terrain at Zhongshan Anchorage, which, once triggered by geological hazards such as earthquakes and ice falls, would be a threat to the usage and maintenance of the anchorage.

  10. 241-U-701 new compressor building and instrument air piping analyses

    Energy Technology Data Exchange (ETDEWEB)

    Huang, F.H.

    1994-08-25

    Building anchorage analysis is performed to qualify the design of the new compressor building foundation given in the ECN ``241-U-701 New Compressor Building.`` Recommendations for some changes in the ECN are made accordingly. Calculations show that the 6-in.-slab is capable of supporting the pipe supports, and that the building foundation, air compressor and dryer anchorage, and electric rack are adequate structurally. Analysis also shows that the instrument air piping and pipe supports for the compressed air system meet the applicable code requirements and are acceptable. The building is for the U-Farm instrument air systems.

  11. Asymmetry a challenge for orthodontists

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    planes of space. A systematic approach to the identification of the cause of the asymmetry head precede the decision whether to correct or to camouflage. The definition of a specific treatment goal should be done only following an analysis of the likelihood that the force system necessary to perform...... the required tooth displacements can be generated. In order to control the interaction between the force systems developed in the three planes of space, the appliances should commonly be segmented. Anchorage problems can occasionally only be solved by means of skeletal anchorage....

  12. 33 CFR 110.87 - Henderson Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.87 Henderson Harbor, N.Y. (a) Area A. The area in the... latitude 43°51′08.8″ N, longitude 76°12′08.9″ W, thence to latitude 43°51′09.0″ N, longitude 76°12′19.0″ W, thence to latitude 43°51′33.4″ N, longitude 76°12′19.0″ W, thence to latitude 43°51′33.4″ N, longitude...

  13. University of Texas MD Anderson: Phenotypic Examination of PIK3CA Allelic Series using In Vitro/In Vivo Sensor Platforms | Office of Cancer Genomics

    Science.gov (United States)

    The CTD2 Center at the University of Texas MD Anderson Cancer Center utilized an established and operational MCF10A normal breast epithelial cell model to assess the ability of candidate driver aberrations to promote cell grow in anchorage-independent conditions (soft agar assay) and proliferate in the absence of insulin and epidermal growth factor (EGF).

  14. Species Profiles. Life Histories and Environmental Requirements of Coastal Fishes and Invertebrates (Pacific Southwest). BLACK, GREEN, and RED ABALONES.

    Science.gov (United States)

    1985-03-01

    The California, to Bahia Santa Maria , Baja outer edge of the shell protrudes over California Sur, Mexico, including the a nacreous surface forming a...Service 1011 E. Tudor Road Anchorage. Alaska 99503 - • , ,. .,>? - , , .. - ..’".;":".".’. : ,’.:; .:.’..’..’..,,.:.’.,v.,.::,;, Al . 1,0_6 ’.1 FILMED 1-86 -DTIC 2 V|

  15. Actomyosin organisation for adhesion, spreading, growth and movement in chick fibroblasts

    DEFF Research Database (Denmark)

    Couchman, J R; Rees, D A

    1979-01-01

    for anchorage-dependent growth, rather than facilitate their movement. The fibroblasts specialized for movement from the explants, though equally well spread, make contact with substratum through extensive areas of relatively unspecialized membrane, have less well developed stress fibres and a low growth rate....

  16. It's Not a Matter of Time: Highlights from the 2011 Competency-Based Summit

    Science.gov (United States)

    Sturgis, Chris; Patrick, Susan; Pittenger, Linda

    2011-01-01

    From Anchorage, Alaska, to Orlando, Florida, and from Gray, Maine, to Yuma, Arizona, one hundred competency-based innovators gathered at the Competency-Based Learning Summit in March 2011. Sponsored by the Council of Chief State School Officers (CCSSO) and the International Association for K-12 Online Learning (iNACOL), the Summit was developed in…

  17. 78 FR 8577 - Final Environmental Impact Statement; Izembek National Wildlife Refuge Proposed Land Exchange...

    Science.gov (United States)

    2013-02-06

    ... of the message. Fax: Attn: Stephanie Brady, Project Team Leader, (907) 786-3965. U.S. Mail: Stephanie Brady, Project Team Leader, U.S. Fish and Wildlife Service, 1011 East Tudor Rd., MS-231, Anchorage, AK... their national and international significance. Congress designated the wilderness area for...

  18. 77 FR 16059 - Draft Environmental Impact Statement; Izembek National Wildlife Refuge Land Exchange/Road...

    Science.gov (United States)

    2012-03-19

    ... the message. Fax: Attn: Stephanie Brady, Project Team Leader, (907) 786-3965. U.S. Mail: Stephanie Brady, Project Team Leader, U.S. Fish and Wildlife Service, 1011 East Tudor Rd., MS-231, Anchorage, AK... and international significance. Congress designated the wilderness area for its...

  19. Report of a Class I bimaxillary dental protrusion case with extraction of first premolars treated with Clarity™ SL MBT appliances

    Directory of Open Access Journals (Sweden)

    Hugo Trevisi

    2013-01-01

    Full Text Available Bimaxillary protrusion cases are common in orthodontic practice. For the best facial outcome, the biomechanics can often be challenging. A class I bimaxillary protrusion case is presented below illustrating the careful application of extractions and bracket prescription. The case highlights how self-ligating brackets and high precision bracket positioning can reduce the need for additional anchorage.

  20. 33 CFR 166.500 - Areas along the Atlantic Coast.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Areas along the Atlantic Coast. 166.500 Section 166.500 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... Anchorages § 166.500 Areas along the Atlantic Coast. (a) Purpose. Fairways, as described in this section...

  1. 19 CFR 24.24 - Harbor maintenance fee.

    Science.gov (United States)

    2010-04-01

    ... Port descriptions and notations Alabama 1901—Mobile Alaska 3126—Anchorage Includes Seldovia Harbor, and... transporting commercial cargo by water in the business of the owner, lessee or operator of the vessel. (4... intervals of at least once each business day. (5) Humanitarian assistance is considered to be...

  2. 77 FR 303 - Sunshine Act Notice

    Science.gov (United States)

    2012-01-04

    ... session on Tuesday, 24 January 2012, from 10:30 to 12:30 p.m. PLACE: Sheraton Anchorage Hotel, 401 E. 6th... agency processes, personnel, and the budget of the Commission. All other portions of the meeting will...

  3. Bibliography on Cold Regions Science and Technology. Volume 51, Part 1.

    Science.gov (United States)

    1997-12-01

    Photosynthesis, Mosses, Carbon dioxide, Simulation 51-4402 Growth response of subarctic dwarf shrubs, Empetrum nigrum and Vaccinium vitis-idaea, to...Alaska. Piper , R.L., Bennett, R.W., International Symposium on Cold Region Development, 5th, Anchorage, AK, May 4-10, 1997. ISCORD 󈨥. Edited by

  4. 33 CFR 165.1151 - Security Zones; liquefied hazardous gas tank vessels, San Pedro Bay, California.

    Science.gov (United States)

    2010-07-01

    ... anchored at a designated anchorage either inside the Federal breakwaters bounding San Pedro Bay or outside... instructions of the Captain of the Port or his or her designated representative. (3) When any LHG tank vessels approach within 500 yards of a vessel that is moored or anchored, the stationary vessel must stay moored...

  5. 77 FR 65816 - Safety Zone; Large Cruise Ships; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker...

    Science.gov (United States)

    2012-10-31

    ... Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide the Coast Guard in... categorically excluded from further review under paragraph 34(g) of Figure 2-1 of the Commandant Instruction. An... those agreed upon arrangements. (ii) Moored vessels or vessels anchored in a designated anchorage...

  6. 33 CFR 165.1154 - Security Zones; Cruise Ships, San Pedro Bay, California.

    Science.gov (United States)

    2010-07-01

    ... anchored at a designated anchorage either inside the Federal breakwaters bounding San Pedro Bay or outside... instructions of the Captain of the Port or his or her designated representative. (3) When a cruise ship approaches within 100 yards of a vessel that is moored, or anchored, the stationary vessel must stay...

  7. 33 CFR 165.812 - Security Zones; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans...

    Science.gov (United States)

    2010-07-01

    ... and continue while the cruise ship is moored or anchored. (b) Regulations. (1) Entry of persons and.... (iii) Moored vessels or vessels anchored in a designated anchorage area are permitted to remain within... with the instructions of the Captain of the Port New Orleans and designated on-scene U.S. Coast...

  8. 24 CFR 3285.405 - Severe wind zones.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Severe wind zones. 3285.405 Section... DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Anchorage Against Wind § 3285.405 Severe wind zones. When any part of a home is installed within 1,500 feet of a coastline in Wind Zones II or III,...

  9. 24 CFR 3285.406 - Flood hazard areas.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Flood hazard areas. 3285.406 Section 3285.406 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Anchorage Against Wind § 3285.406...

  10. Environmental Impact Statement for the Modernization and Enhancement of Ranges, Airspace, and Training Areas in the Joint Pacific Alaska Range Complex in Alaska. Volume 2 - Appendices A through L

    Science.gov (United States)

    2013-06-01

    Napolitano, Secretary, US Department of Homeland Security Pamela A Bergmann, Regional Environmental Officer, US Department of the Interior Ken Salazar...Alaska Bruce Cain, Operations Advisor, Ahtna Corporation Ken Johns, President and CEO, Ahtna lnc. Matt Wallace, Executive Director, AKPirg...Anchorage, AMFAST Representative Jack Wilber , Alaska State Chamber of Commerce, AMFAST Representative Kennelh Lytl1goe, Non-Airline Tenant Representative

  11. 77 FR 68567 - Announcement of Funding Awards for the Continuum of Care Program for Fiscal Year (FY) 2011

    Science.gov (United States)

    2012-11-15

    ... County. Mental Health Association of San CA 39,530 Mateo County. Mental Health Systems Inc CA 287,042 Mental Health Systems Inc CA 74,843 Mental Health Systems Inc CA 273,283 Merced County Community Action... AIDS Assistance Association.. AK 104,665 Anchorage Community Mental Health AK 646,563 Services,......

  12. 77 FR 7383 - Announcement of Funding Awards for the Continuum of Care Program for Fiscal Year (FY) 2010

    Science.gov (United States)

    2012-02-10

    ...,530 County. Mental Health Association of San Mateo CA 73,271 County. Mental Health Systems Inc CA 273,283 Mental Health Systems Inc CA 287,042 Mental Health Systems Inc CA 74,843 Mental Health Systems Inc... Assistance Association....... AK 104,665 Anchorage Community Mental Health......

  13. 33 CFR 110.245 - Vieques Passage and Vieques Sound, near Vieques Island, P.R.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Vieques Passage and Vieques Sound, near Vieques Island, P.R. 110.245 Section 110.245 Navigation and Navigable Waters COAST GUARD... and Vieques Sound, near Vieques Island, P.R. (a) The anchorage grounds—(1) Vieques Passage...

  14. Hooked… make it simple and easy

    Directory of Open Access Journals (Sweden)

    Sheetal Potnis

    2014-01-01

    Full Text Available Temporary anchorage devices (TADs have solved a lot of orthodontic treatment dilemmas. Attachment of elastomers to these TADs is sometimes difficult, especially with embedded microimplants like in the infrazygomatic area. Here, a simple modification has been made in the attachment of elastomeric chain to ligature wire for ease of replacing the elastomeric chain.

  15. 33 CFR 110.188 - Atlantic Ocean off Miami and Miami Beach, Fla.

    Science.gov (United States)

    2010-07-01

    ... Miami Beach, Fla. (a) The anchorage grounds. The area to the eastward of a line bearing 12° (N. 12° E.) through a point X, which is 11/2 nautical miles due east of the intersection of the Miami Beach shore line... Miami Beach, Fla. 110.188 Section 110.188 Navigation and Navigable Waters COAST GUARD, DEPARTMENT...

  16. 77 FR 14350 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-03-09

    ...; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... Hilton Hotel, 500 West 3rd Avenue, King Salmon/Illiamna Room, Anchorage, AK. Council address: North... INFORMATION CONTACT: Jane DiCosimo, Council staff; telephone: (907) 271-2809. SUPPLEMENTARY INFORMATION:...

  17. 78 FR 16660 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-03-18

    ...; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... Hilton Hotel, Dillingham/Katmai Room, 500 West 3rd Avenue, Anchorage, AK. Council address: North Pacific... CONTACT: Diana Evans, Council staff, telephone: (907) 271-2809. ] SUPPLEMENTARY INFORMATION: The...

  18. 76 FR 11978 - Proposed Amendment of Federal Airways; Alaska

    Science.gov (United States)

    2011-03-04

    ... Federal airways in Alaska. Due to construction of wind turbines on Fire Island, AK, the Anchorage VOR is... after the closing date for comments. A report summarizing each substantive public contact with FAA... technical regulations for which frequent and routine amendments are necessary to keep them...

  19. The politics of symmetry

    NARCIS (Netherlands)

    Pels, D.L.

    1996-01-01

    While symmetry and impartiality have become ruling principles in S&TS, defining its core ideal of a 'value-free relativism', their philosophical anchorage has attracted much less discussion than the issue or:how far their jurisdiction can be extended or generalized. This paper seeks to argue that sy

  20. Mother, wife and role model

    DEFF Research Database (Denmark)

    Ørjasæter, Kristin

    2005-01-01

    By reconstructing the contemporary discussion on womens emancipation, and its roots, the article traces the motifs and liberation projects in A Doll's House back to Camilla Collett, the leading Norwegian pioneer on womens liberation. The article thus discusses problematic issues that easily get l...... lost when one approaches A Doll's House with theoretical anchorage in modern feminist theory....

  1. 75 FR 8791 - Continuation of the National Emergency Relating to Cuba and of the Emergency Authority Relating...

    Science.gov (United States)

    2010-02-25

    ... transmitted to the Congress. (Presidential Sig.) THE WHITE HOUSE, February 23, 2010. [FR Doc. 2010-4107 Filed... Notice of February 23, 2010--Continuation of the National Emergency Relating to Cuba and of the Emergency... Emergency Relating to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage...

  2. 76 FR 82114 - Amendment of VOR Federal Airways V-320 and V-440; Alaska

    Science.gov (United States)

    2011-12-30

    ... and efficient management of Instrument Flight Rules (IFR) operations within the National Airspace... Anchorage VOR navigation aid (76 FR 68674). Interested parties were invited to participate in this... (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a regulatory evaluation...

  3. 78 FR 65173 - Airworthiness Directives; Airbus Airplanes

    Science.gov (United States)

    2013-10-31

    ... bearing installation of the retraction jack anchorage fitting in the main landing gear (MLG) were incorrectly manufactured. This AD requires an inspection of the left-hand (LH) and right-hand (RH) bearing... CONTACT: Sanjay Ralhan, Aerospace Engineer, International Branch, ANM-116, Transport Airplane...

  4. 33 CFR 110.230 - Puget Sound Area, Wash.

    Science.gov (United States)

    2010-07-01

    .... (7) Smith Cove General Anchorage (west), Elliott Bay. Shoreward of a line beginning at Fourmile Rock Light; thence to a point bearing 207°, 1,100 yards, from Fourmile Rock Light; thence southeasterly to a... constructed of wood shall, unless there are steel bulwarks or metallic cases or cargo on board, be fitted...

  5. 78 FR 66916 - Alaskan Seafood Processing Effluent Limitations Guidelines

    Science.gov (United States)

    2013-11-07

    ... included in the original or supplemental petition because the location met the statutory criteria for BPT.... Location-by-Location Analysis 1. Anchorage 2. Cordova 3. Juneau 4. Ketchikan 5. Petersburg VIII... entities likely to be affected by this notice. Other types of entities that do not meet the above...

  6. Boat-Wave-Induced Bank Erosion on the Kenai River, Alaska

    Science.gov (United States)

    2008-03-01

    72 Table 14. Erosion rates as determined by Scott (1982).......................................................................83...Anchorage – Orson Smith (PhD engineer); Alaska Department of Environmental Conservation – Jim Rypkema (water quality), Kent Patrick-Riley (water quality...interspersed with coarse strata from fluvial outwash. Both the bed material and the channel pattern reflect previous glacial discharges ( Scott 1982) and

  7. 14 CFR 93.69 - Special requirements, Lake Campbell and Sixmile Lake Airports.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Special requirements, Lake Campbell and... Anchorage, Alaska, Terminal Area § 93.69 Special requirements, Lake Campbell and Sixmile Lake Airports. Each person operating an aircraft to or from Lake Campbell or Sixmile Lake Airport shall conform to the...

  8. 29 CFR 1926.758 - Systems-engineered metal buildings.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Systems-engineered metal buildings. 1926.758 Section 1926... Systems-engineered metal buildings. (a) All of the requirements of this subpart apply to the erection of systems-engineered metal buildings except §§ 1926.755 (column anchorage) and 1926.757 (open web...

  9. Connections in Precast Buildings using Ultra High-Strength Fibre Reinforced Concrete

    DEFF Research Database (Denmark)

    Hansen, Lars Pilegaard

    1995-01-01

    Ultra high-strength concrete adds new dimensions to the design of concrete structures. It is a brittle material but introducing fibres into the matrix changes the material into a highly ductile material. Furthermore, the fibre reinforcement increases the anchorage of traditional reinforcement bars...

  10. 77 FR 11377 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2012-02-24

    ... With Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and..., 2012 Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority....-registered civilian aircraft in international airspace north of Cuba. On February 26, 2004, by...

  11. 78 FR 13207 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2013-02-26

    ... Emergency With Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage... ] Notice of February 22, 2013 Continuation of the National Emergency With Respect to Cuba and of the....-registered civilian aircraft in international airspace north of Cuba. On February 26, 2004, by...

  12. 76 FR 11071 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2011-02-28

    ... Emergency With Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage... ] Notice of February 24, 2011 Continuation of the National Emergency With Respect to Cuba and of the....-registered civilian aircraft in international airspace north of Cuba. On February 26, 2004, by...

  13. 76 FR 77309 - Office of Hazardous Materials Safety; Notice of Delays in Processing of Special Permits Applications

    Science.gov (United States)

    2011-12-12

    ...), Anchorage, AK. 4850-R Halliburton Energy Services, 4 03-31-2012 Inc., Duncan, OK. 6691-R nexAir, LLC.... 15334-N Floating Pipeline Company 4 03-31-2012 Incorporated, Halifax, Nova Scotia. 15322-N Digital Wave...., King of Prussia, PA 4 03-31-2012 Party to Special Permits Application 10880-P Southwest Energy...

  14. 33 CFR 110.156 - Randall Bay, Freeport, Long Island, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Randall Bay, Freeport, Long Island, N.Y. 110.156 Section 110.156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND....Y. (a) The anchorage grounds. Southward of a line 312 feet south of and parallel to the south...

  15. American Occupation

    Institute of Scientific and Technical Information of China (English)

    CHEN WEN

    2011-01-01

    The "Occupy Wall Street" protests have grown from an insignificant lower Manhattan gathering of around 1,500 people to tens of thousands of people across the United States,from Anchorage,Alaska to Tampa,Florida.The protests started on September 17,denouncing the greed and recklessness of the financial titans who brought down the U.S.economy.

  16. Encoding the Shipping Crisis

    Institute of Scientific and Technical Information of China (English)

    Xue Lina; Lin Lin; Wang Siyuan

    2009-01-01

    @@ According to the statistics from Frech shipping advisory bod-ies,till December 21,2008,165 container ships were idle,leav-ing the fees,such as anchorage fees,ship maintaining fee,crev resettlement fee and repaying loans for ship-buying,an-noying the ship-owners.

  17. Preliminary interpretation of industry two-dimensional seismic data from Susitna Basin, south-central Alaska

    Science.gov (United States)

    Lewis, Kristen A.; Potter, Christopher J.; Shah, Anjana K.; Stanley, Richard G.; Haeussler, Peter J.; Saltus, Richard W.

    2015-07-30

    Located approximately 80 kilometers northwest of Anchorage, Alaska, the Susitna Basin is a complex sedimentary basin whose tectonic history has been poorly understood. Recent interpretation of two-dimensional seismic reflection data integrated with well, aeromagnetic, and gravity data provides new insights into the structural and stratigraphic nature of the basin.

  18. Nonlinear Disturbance Rejection for Magnetic Levitation Systems

    Science.gov (United States)

    2003-10-01

    B. Costic, D. Dawson and Y. Fang, "Non- linear Control of Magnetic Bearing in the Presence of Sinu- soidal Disturbance," Proceedings of the American Control Conference , pp...Unknown 61 Amplitudes and Frequencies in Linear SISO Uncertain Sys- tems," Proceedings of the American Control Conference , Anchorage, Alaska, pp. 4015

  19. State-Space Search for Improved Autonomous UAVs Assignment Algorithm

    Science.gov (United States)

    2004-12-01

    Proceedings of the American Control Conference , Anchorage, Alaska, 2002. [2] Guo, W. and Nygard, K., “Combinatorial Trading...Resource Allocation,” Proceedings of the American Control Conference , Arlington, Vir- ginia, 2001. [5] Schumacher, C. J., Chandler, P. R., and Rasmussen...and Loitering,” Proceedings of the American Control Conference , Denver, Colorado, 2003. [7] Rasmussen, S.

  20. Helping General Physical Educators and Adapted Physical Educators Address the Office of Civil Rights Dear Colleague Guidance Letter: Part III--Practitioners and Programs

    Science.gov (United States)

    Poulin, David; Martinez, David; Aenchbacher, Amy; Aiello, Rocco; Doyle, Mike; Hilgenbrinck, Linda; Busse, Sean; Cappuccio, Jim

    2013-01-01

    In Part III of the feature, physical educators and adapted physical educators offer current best practices as models of implementation for readers. Contributions included are: (1) Answer to the Dear Colleague Letter from the Anchorage School District's Adapted Sport Program (David Poulin); (2) Georgia's Adapted Physical Educators Response to the…

  1. 76 FR 68674 - Proposed Amendment of VOR Federal Airways V-320 and V-440; Alaska

    Science.gov (United States)

    2011-11-07

    ... that V-320 and V-440 did not have satisfactory signal reception coverage in the vicinity of Anchorage..., 2011). This action would amend the above airways as the signal reception of the relocated navigation... will be subject to an environmental analysis in accordance with FAA Order 1050.1E,...

  2. 32 CFR Appendix D to Part 45 - State Directors of Veterans Affairs

    Science.gov (United States)

    2010-07-01

    ..., MILITARY AND CIVILIAN CERTIFICATE OF RELEASE OR DISCHARGE FROM ACTIVE DUTY (DD FORM 214/5 SERIES) Pt. 45..., Department of Military & Veterans Affairs, 3601 C Street, suite 620, Anchorage, AK 99503. American Samoa..., Johnston, IA 50131-1902. Kansas Executive Director, Kansas Veterans Commission, Jayhawk Tower, suite...

  3. 改良腭弓矫治后牙锁节对后牙功能恢复的影响%Influence of promote palatine arch treating buccal teeth lock on occlusion function recovery of buccal teeth

    Institute of Scientific and Technical Information of China (English)

    马宁; 孙应明; 白槐延

    2002-01-01

    @@ Background: Buccal teeth occlusion lock is a kind of common malocclusion malformation in orthodonic clinic. Traditional treatment to buccal teeth occlusion lock is interactive traction of upper and lower buccal teeth.This treatment had shortcoming such as insufficient anchorage and elongation of buccal teeth.We adopted promote fix palatine arch therapy, which recovery patients' occlusion function by clinical observation.

  4. Twin - Arch technique. Revival of the "edgewise -Technique"?

    Directory of Open Access Journals (Sweden)

    Jacob Karp

    2012-01-01

    The SNB – Bracket brings a new dimension into the orthodontic world which is most apparent in extraction cases. Its Teflon – like material has a very low friction coefficient thus, reducing the treatment time considerably. Through the use of low dimensioned arch wires, the Twin – Arch Technique becomes a Light – wire system and simultaneously provides good anchorage and torque control.

  5. Comparison of Acoustic and Aerial Photographic Methods for Quantifying the Distribution of Submersed Aquatic Vegetation in Sagamore Creek, NH

    Science.gov (United States)

    2008-03-01

    anchorage (also 6 ft deep) at MLLW. The project is home port to a small commercial lobster fishing fleet as well as numerous recreational vessels...Change Analysis Program (http://www.csc.noaa.gov/crs/ lca /ccap.html). Boat- based visual ground-truth surveys conducted on 23 August and 9 September

  6. 24 CFR 3285.403 - Sidewall, over-the-roof, mate-line, and shear wall straps.

    Science.gov (United States)

    2010-04-01

    ..., and shear wall straps. 3285.403 Section 3285.403 Housing and Urban Development Regulations Relating to... Anchorage Against Wind § 3285.403 Sidewall, over-the-roof, mate-line, and shear wall straps. If sidewall, over-the-roof, mate-line, or shear wall straps are installed on the home, they must be connected to...

  7. 33 CFR 110.207 - Cleveland Harbor, Ohio.

    Science.gov (United States)

    2010-07-01

    ... opposite Cleveland East Entrance Light to a due north line passing through the flashing white light on the... Breakwater from Cleveland West Breakwater Light. (2) East anchorage. The southeasterly portion of the East... and distances from Cleveland East Pierhead Light: 38°30′, 2,050 feet; 68°, 2,050 feet; 57°, 7,050...

  8. 33 CFR 110.134 - Portland Harbor, Maine.

    Science.gov (United States)

    2010-07-01

    ... north by a line running 90° from House Island Light to Peak Island; on the east by the western shore of... Island Light; thence along the western shore of House Island to Fort Scammel Point Light; thence 325° for... westernmost point on Cushing Island to Fort Scammel Point Light. (b) The regulations. (1) Anchorage B...

  9. 33 CFR 110.212 - Newport Bay Harbor, Calif.

    Science.gov (United States)

    2010-07-01

    ... at the east end of Lido Isle; north of a line parallel to and 250 feet north of a line bearing 268° from Newport Bay Channel Light 11, this line being the north line of the main fairway; northwest of a... parallel to the existing pierhead line, and adjoining and on the north side of Anchorage C-3 described...

  10. 76 FR 13360 - North Pacific Fishery Management Council; Public Meetings

    Science.gov (United States)

    2011-03-11

    .../approve salmon excluder EFP; review discussion paper on AFA impacts on Bering Sea cod trawlers. 10. Staff... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE... Hotel, 500 West 3rd Avenue, Anchorage, AK. Council address: North Pacific Fishery Management...

  11. Economic Education Experiences of Award Winning Alaska Teachers.

    Science.gov (United States)

    Thomas, Monica, Ed.

    Award-winning economic education projects devised by Alaska teachers included three elementary (K-6) projects and three second level (7-12) ones. Faith Greenough's students (Chinook Elementary School, Anchorage) compared Tlingit traditional and market economies in Alaska, so economics became an integrated part of elementary instruction. Marie…

  12. Changes in the Arctic: Background and Issues for Congress

    Science.gov (United States)

    2014-04-28

    et al., Report of the Indigenous Peoples’ Global Summit on Climate Change: 20-24 April 2009, Anchorage, Alaska ( Darwin , Australia: United Nations...living in the Arctic, including floods or forest fires, were also urgently need[ed], the report said.210 Coast Guard Statements A January 2011 press

  13. CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells.

    Science.gov (United States)

    Suyama, Kumi; Onishi, Hideya; Imaizumi, Akira; Shinkai, Kentaro; Umebayashi, Masayo; Kubo, Makoto; Mizuuchi, Yusuke; Oda, Yoshinao; Tanaka, Masao; Nakamura, Masafumi; Katano, Mitsuo

    2016-04-28

    Hedgehog (Hh) signaling has been found to be activated in breast cancer stem cells (BCSCs). However, the precise role of the BCSCs marker, CD24, remains unclear. Here, we describe a relationship between CD24 and Sonic Hedgehog (SHH), and reveal a role for this relationship in the induction of a malignant phenotype of breast cancer. CD24 siRNA-transfected breast cancer cells (BCCs) demonstrated higher expression of SHH and GLI1, increased anchorage-independent proliferation, and enhanced invasiveness and superior tumorigenicity compared with control. Conversely, CD24 forced-expressing BCCs possessed decreased SHH and GLI1 expression, anchorage-independent proliferation, and invasiveness. Suppression of SHH decreased invasiveness through inhibition of matrix metalloproteinase (MMP)-2 expression, GLI1 expression, anchorage-independent proliferation, tumorigenicity, and tumor volume in vivo in CD24 siRNA transfected BCCs. DNA microarray analysis identified STAT1 as a relationship between CD24 and SHH. CD24 siRNA-transfected BCCs with concurrent STAT1 inhibition exhibited decreased SHH expression, invasiveness, anchorage-independent proliferation, tumorigenicity, and tumor volume in vivo. These results suggest that CD24 suppresses development of a malignant phenotype by down-regulating SHH transcription through STAT1 inhibition. CD24 gene transfer or STAT1 inhibition may represent new effective therapeutic strategies to target refractory breast cancer.

  14. 33 CFR 110.138 - Boston Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... Island Anchorage. Beginning at a point bearing 93°, 1,400 yards, from the aerial beacon on top of the Boston Custom House tower; thence to a point bearing 81°, 1,600 yards, from the aerial beacon on top of the Boston Custom House tower; thence to a point bearing 102°, 3,100 yards, from the aerial beacon...

  15. Using Personnel Evaluation To Focus on the Development of Teaching Skills: Faculty Ideas and University Policy.

    Science.gov (United States)

    O'Leary, Neil; Fenton, Ray

    The role of the personnel evaluation process in improving the performance of teachers as classroom communicators is explored by contrasting the personnel evaluation system of Alaska Pacific University (APU) with that of the Anchorage School District (Alaska). While the APU system offers little specification for formative evaluation activities, the…

  16. Instructions for collecting and dispatch of living tropical Lemnaceae

    NARCIS (Netherlands)

    Landolt, E.

    1957-01-01

    1. Occurrence.--Lemnaceae may occur in stagnant or sluggish streaming waters, specially in ditches, pools, streamlets, inundated rice-fields, etc. They are also found in all other waters in which larger swamp plants offer anchorage to the tiny Lemnaceae. They can be expected between stands of sedges

  17. Un error en los calculos matematicos destroza el acelerador de particulas del CERN

    CERN Multimedia

    Cernuda, Olalla

    2007-01-01

    The most famous particle accelerator in the world, who is at CERN, has suffered a catastrophic damage after a great explosion took place in its depths. This explosion has an absolutely scientific explanation: a mathematical mistake in the design of the anchorages of great magnets. (1 page)

  18. 75 FR 7517 - Notice of Intent To Prepare an Amendment to the Ring of Fire Resource Management Plan for the...

    Science.gov (United States)

    2010-02-19

    ... that are best suited to local, regional, and national needs and concerns. The preliminary issues and... Appendix C of the BLM Land Use Planning Handbook (H-1601-01); Identify development needs for the existing... scoping meetings in Anchorage through local news media, newsletters, and the BLM Web site (...

  19. 33 CFR 109.15 - Enforcement proceedings.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Enforcement proceedings. 109.15... GENERAL § 109.15 Enforcement proceedings. Proceedings against a vessel violating the Anchorage Regulations... of the Port. When the vessel is at a port where there is no Coast Guard officer, proceedings will...

  20. Port and Waterways Safety Assessment Workshop Report, New York

    Science.gov (United States)

    2008-09-01

    security zone • Claremont Channel – barge fleeting /mooring area • PST cruise ship terminal area • Anchorage FA 19 in Hudson used for fleeting...Van Kull o Hess Bayonne terminal o New cruise ship terminal in Bayonne when taking on bunkers • Container terminal soundings are not well