WorldWideScience

Sample records for anchorages

  1. TERRAIN, Anchorage, Alaska

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Anchorage AOI consists of seven areas. These areas were to be collected to the 'highest' accuracy requirement. Ground Control is collected throughout the AOI...

  2. Alarm in Anchorage.

    Science.gov (United States)

    Campbell, Larry

    1991-01-01

    A possible sex scandal involving a teacher and a teenage student rocked the community in Anchorage, Alaska. Privacy and labor laws and union contract forbade board members from discussing the retirement deal that had been negotiated with the accused teacher. Hindsight suggests board members should have shared what information they could with the…

  3. Temporary Anchorage Device: An Epitome of Anchorage in Orthodontic Treatment

    Science.gov (United States)

    Nayak, US Krishna; Hegde, Amitha M; Jacob, Mary

    2011-01-01

    One of the most important phases of oral health is the form and function of the oral mechanism. Recently, pediatric dentists are concerned with the obvious esthetic disabilities and the pathologic implications of the malposed teeth. Interceptive and functional orthodontic treatment is playing a major role in these discrepancies. Anchorage is an important consideration in orthodontics, particularly if force is applied entirely to the teeth. For many years, clinicians have searched for a form of anchorage that does not rely on patient cooperation. During the last few decades, a wealth of new information has accumulated to such an extent that the present authors thought it appropriate to let these advances make an impact by suggesting a revised definition and classification of anchorage. This paper also gives a brief insight on evolution of anchorage and its application in pediatric dentistry.

  4. [Bone-based anchorage failure].

    Science.gov (United States)

    Mer, Grégoria; Brezulier, Damien; Sorel, Olivier

    2016-03-01

    The aim of this article is to list the circumstances likely to give rise to failure of orthodontic temporary bone-supported anchorage and, hence, to attempt to define criteria for correct miniscrew usage. Our study was based on a review of the literature and analyses of clinical cases. Our findings show that, with a sound knowledge of the indications for screw selection and positioning and of the insertion protocols combined with a clear understanding of orthodontic mechanics, bone-based anchorage can henceforth provide orthodontists with an essential tool to enable formerly unachievable dental movements and to stabilize unwanted movements, thus making treatment both more reliable and more effective. PMID:27083224

  5. New concept of physiologic anchorage control

    OpenAIRE

    Tian-Min Xu

    2015-01-01

    Molar anchorage loss in extraction case is believed due to the reaction of mechanical force applied to retract anterior teeth. While it may be close to truth in adult patients, it is certainly not true in adolescents. Studies on molar growth show upper molar move forward as mandible growing forward, probably through intercuspation force. Hence, for adolescents, molar anchorage loss shall consist of two parts. One is from retraction force - mechanical anchorage loss; another from biologic forc...

  6. Orthodontic Anchorage Implants: State-of-the-art

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    The limits of an orthodontic treatment are often set by the lack of suitable anchorage. The mini-implant is used where conventional anchorage cannot be applied and not as a replacement for conventional anchorage. In patients with lack of teeth and reduced periodontium, skeletal anchorage allows...... will improve the reconstruction possibilities. The mini-implant has widened the orthodontic possibilities....

  7. 76 FR 76295 - Anchorage Regulations; Wells, ME

    Science.gov (United States)

    2011-12-07

    ... rulemaking (NPRM) entitled ``Anchorage Regulations; Wells, Maine'' in the Federal Register (76 FR 52599). We..., Maine. All coordinates referenced use datum: NAD 83. Dated: November 21, 2011. Daniel A. Neptun,...

  8. Is skeletal anchorage changing the limit of orthodontics?

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    The limits for orthodontic treatment are often set by the lack of suitable anchorage. The mini-implant is used where conventional anchorage cannot be applied; not as a replacement for conventional anchorage. In patients with lack of teeth and reduced periodontium, skeletal anchorage allows...... and can be loaded immediately. The course will be addressed the following topics: Are the mini-implants replacing conventional anchorage? Why are orthodontic mini-implants necessary? The development of the skeletal anchorage systems The biological basis for the skeletal anchorage systems...... The characteristics of the different skeletal anchorage systems The insertion procedure The indications for the use of orthodontic mini-implants Treatment planning in relation to the use of mini-implants Case presentations...

  9. Friction does not increase anchorage loading.

    Science.gov (United States)

    Southard, Thomas E; Marshall, Steve D; Grosland, Nicole M

    2007-03-01

    Conventional wisdom suggests that orthodontists must apply added force to overcome friction during canine retraction (sliding mechanics), the result of which can be increased anchorage loading and anchorage loss. However, for a frictional force to be exerted mesially by the archwire against a canine during retraction, the archwire must be compressed between the canine and the anchor molar, and an equal but opposite force must be applied distally against the molar by the archwire. In other words, the frictional force that reduces the force of retraction on the canine must also reduce the protraction force on the molar. Emphasis on employing reduced-friction (eg, self-ligating) brackets during sliding mechanics to prevent added posterior anchorage loading is unwarranted and based more on bracket salesmanship than on orthodontic biomechanics. PMID:17346599

  10. Paradigm shifts in orthodontic treatment with mini-implant anchorage

    Directory of Open Access Journals (Sweden)

    Johnny Joung-Lin Liaw

    2015-01-01

    Full Text Available After the applications of mini-implant anchorage, the envelope of orthodontic treatment was expanded and some treatment modes were changed because of more predictable tooth movement with empowered anchorage. The author tried to share his experience of TADs applications for clarifying the paradigm shifts of orthodontic treatment assisted with the mini-implant anchorage.

  11. Biological reactions to temporary anchorage devices

    NARCIS (Netherlands)

    G. Wu; J. Guo; H. Hu; V. Everts

    2015-01-01

    This chapter reviews the current knowledge of the biological reactions to temporary anchorage devices (TADs) and the factors that affect a successful application of TADs. In addition to clinical investigations, finite element analysis (FEA) is also extensively used to analyze the factors on the mech

  12. Measuring the democratic anchorage of governance networks

    DEFF Research Database (Denmark)

    Fotel, Trine; Sørensen, Eva; Torfing, Jacob

    model helps to assess the democratic performance of specific governance networks and to gain knowledge about the critical factors that determine their degree of democratic anchorage. Such knowledge is crucial for developing proactive strategies for enhancing the democratic performance of specific...

  13. Anchorage of Main Reinforcement in Lightweight Aggregate Concrete Beams

    DEFF Research Database (Denmark)

    Larsen, Henning

    1999-01-01

    The paper deals with the anchorage of reinforcement bars at end supports in beam component made of lightweight aggregate concrete with open structure.......The paper deals with the anchorage of reinforcement bars at end supports in beam component made of lightweight aggregate concrete with open structure....

  14. 75 FR 76275 - Anchorage Regulations; Long Island Sound

    Science.gov (United States)

    2010-12-08

    ...In this rule the Coast Guard establishes seven anchorage grounds in Long Island Sound. These anchorages are located in Connecticut and New York State waters. This action is necessary to aid in facilitating the safe and secure anchoring and transiting of vessels, particularly deep draft vessels, transiting Long Island Sound or awaiting entry to a port or facility in New York and...

  15. Mechanical anchorage of FRP tendons – A literature review

    DEFF Research Database (Denmark)

    Schmidt, Jacob W.; Bennitz, Anders; Täljsten, Björn;

    2012-01-01

    anchorage systems for use with Aramid, Glass and Carbon FRP tendons have been proposed over the last two decades. Each system is usually tailored to a particular type of tendon. This paper presents a brief overview of bonded anchorage applications while the primary literature review discusses three methods...

  16. FRP tendon anchorage in post-tensioned concrete structures

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Täljsten, Björn; Bennitz, Anders;

    2008-01-01

    effective Young´s modulus and the high stress capacity in the linear elastic range of the material. The use of external tendons increases the requirements on the anchorage systems. This is in particular important when using un-bonded tendon systems, where the anchorage and deviators are the only force...

  17. [Zygomatic anchorage concept in full edentulism].

    Science.gov (United States)

    Malevez, C

    2012-09-01

    The zygoma anchorage concept for severe atrophy of the maxilla was developed by Brånemark in the 1980s. It concerned patients having undergone maxillectomy as well as patients with edentulous upper jaws and mild to severe maxillary atrophy. The concept was created and clinically developed in 1997, by placing two zygomatic implants and four standard ones to compensate sub-sinus bone resorption. It was applied later to patients presenting extremely severe maxillary atrophy, using the "zygoma quad" concept with the placement of four zygomatic implants. Zygoma anchorage is reliable in terms of osseo-integration and biomechanical support of screwed prostheses, according to frequently published data (overall survival rate ranging between 91 and 100%). The increasing practice of immediate loading makes it the treatment of choice for oral rehabilitation. It decreases surgical invasiveness and the delay between surgery and oral rehabilitation. It allows a quick social and professional reinsertion and increases the comfort and quality of life for patients with fully edentulous maxilla with mild, moderate, or severe atrophy. PMID:22920891

  18. 78 FR 3326 - Safety Zone Within the Lower Portion of Anchorage #9, Mantua Creek Anchorage; Paulsboro, NJ

    Science.gov (United States)

    2013-01-16

    ... 20590, between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. FOR FURTHER... of Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking A. Regulatory History and... Anchorage 9 (Mantua Creek Anchorage) due to dredging operations. The Dredge Florida will be working...

  19. Anchorage Arrival Scheduling Under Off-Nominal Weather Conditions

    Science.gov (United States)

    Grabbe, Shon; Chan, William N.; Mukherjee, Avijit

    2012-01-01

    Weather can cause flight diversions, passenger delays, additional fuel consumption and schedule disruptions at any high volume airport. The impacts are particularly acute at the Ted Stevens Anchorage International Airport in Anchorage, Alaska due to its importance as a major international portal. To minimize the impacts due to weather, a multi-stage scheduling process is employed that is iteratively executed, as updated aircraft demand and/or airport capacity data become available. The strategic scheduling algorithm assigns speed adjustments for flights that originate outside of Anchorage Center to achieve the proper demand and capacity balance. Similarly, an internal departure-scheduling algorithm assigns ground holds for pre-departure flights that originate from within Anchorage Center. Tactical flight controls in the form of airborne holding are employed to reactively account for system uncertainties. Real-world scenarios that were derived from the January 16, 2012 Anchorage visibility observations and the January 12, 2012 Anchorage arrival schedule were used to test the initial implementation of the scheduling algorithm in fast-time simulation experiments. Although over 90% of the flights in the scenarios arrived at Anchorage without requiring any delay, pre-departure scheduling was the dominant form of control for Anchorage arrivals. Additionally, tactical scheduling was used extensively in conjunction with the pre-departure scheduling to reactively compensate for uncertainties in the arrival demand. For long-haul flights, the strategic scheduling algorithm performed best when the scheduling horizon was greater than 1,000 nmi. With these long scheduling horizons, it was possible to absorb between ten and 12 minutes of delay through speed control alone. Unfortunately, the use of tactical scheduling, which resulted in airborne holding, was found to increase as the strategic scheduling horizon increased because of the additional uncertainty in the arrival times

  20. Urban contaminants project: Fish and Hood Creeks, Anchorage, Alaska

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Urbanization has decreased water quality and adversely impacted biological communities in the lakes and streams of Anchorage, Alaska (Hock, 1981; Brabets, 1987;...

  1. Minor tooth movements using microimplant anchorage: case reports.

    Science.gov (United States)

    Sohn, Dong-Seok; Lee, Jung-Kwang; An, Kyung-Mi

    2008-03-01

    For the treatment of extruded or tipped molars, various conventional techniques have been used. But those methods may lead to undesirable movement of the anchorage units and lengthen treatment time because of limited tooth-borne anchorage potential. Introduction of microimplants as orthodontic anchorage has expanded treatment possibilities because of their advantages. Some advantages are a less complex surgical procedure, decrease in cost, immediate loading, and their ability to be placed in any area of the alveolar bone. This article will illustrate clinical experiences in patients who were treated with the intrusion of overerupted molars, the up-righting of tilted molars, and other clinical applications for minor tooth movements. Anchorage control was achieved with the surgical insertion of titanium microimplants for immediate loading in the alveolar bone. When needed, minimal fixed appliances were used and orthodontic treatment was completed without any other complications.

  2. 78 FR 44917 - Anchorage Regulations; Port of New York

    Science.gov (United States)

    2013-07-25

    ...The Coast Guard proposes to establish and modify anchorage grounds within the Port of New York. This action is necessary to facilitate safe navigation and provide safe and secure anchorages for vessels operating in the area. This proposed rule is intended to increase the safety of life and property of both the anchored vessels and those operating in the area as well as provide for the overall......

  3. 76 FR 20524 - Anchorage Regulations; Port of New York

    Science.gov (United States)

    2011-04-13

    ...The Coast Guard is revising Anchorage Ground No. 19 located east of the Weehawken-Edgewater Federal Channel on the Hudson River. The revision is necessary to facilitate safe navigation and provide safe and secure anchorages for vessels operating in the area. This action is intended to increase the safety of life and property of both the anchored vessels and those operating in the area as well......

  4. Clinical applications of orthodontic microimplant anchorage in craniofacial patients.

    Science.gov (United States)

    Vachiramon, Amornpong; Urata, Mark; Kyung, Hee Moon; Yamashita, Dennis-Duke; Yen, Stephen L-K

    2009-03-01

    Microimplant anchors, also known as temporary anchorage devices, mini- and micro-screws, have been used to enhance orthodontic anchorage for difficult tooth movements. Here, the authors describe how microimplants can be used to help treat craniofacial patients by supporting distraction osteogenesis procedures, maxillary protraction procedures, cleft segment expansion and stabilization, and tooth movement into narrow alveolar cleft sites. While most craniofacial patients are treated without microimplants, it would be worthwhile to identify which cases could benefit from microimplant anchorage. As an adjunct to orthodontic treatment, the microimplant offers a potential method for solving troublesome orthodontic and surgical problems such as guiding distraction procedures with orthodontics when primary teeth are exfoliating, addressing residual maxillary cants after vertical distraction osteogenesis of a ramus, stabilizing an edentulous premaxilla, and moving teeth into atrophic alveolar ridges. These cases are presented to open a dialogue on their possible uses in craniofacial patients.

  5. 76 FR 21633 - Disestablishing Special Anchorage Area 2; Ashley River, Charleston, SC

    Science.gov (United States)

    2011-04-18

    ... the developer has no riparian rights to the land beneath Ashley River Anchorage 2, and that the... the proposal by The City Marina should have any impact on disestablishing Ashley River Anchorage 2. While relocation of the channel could impact the location of part of Ashley River Anchorage 1, it...

  6. Shear and anchorage behaviour of fire exposed hollow core slabs

    NARCIS (Netherlands)

    Fellinger, J.

    2005-01-01

    The fire resistance of hollow core slabs is currently assessed considering flexural failure only. However, fire tests show that shear or anchorage failure can also govern the load bearing behaviour. This paper is based on the dissertation by the author1 and discusses existing and new fire tests. It

  7. 75 FR 3641 - Television Broadcasting Services; Anchorage, AK

    Science.gov (United States)

    2010-01-22

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Anchorage, AK AGENCY: Federal Communications... Congressional review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television,...

  8. 75 FR 22323 - Anchorage Regulations; Port of New York

    Science.gov (United States)

    2010-04-28

    ... SECURITY Coast Guard 33 CFR Part 110 RIN 1625-AA01 Anchorage Regulations; Port of New York AGENCY: Coast...-mail Mr. Jeff Yunker, Coast Guard Sector New York, Waterways Management Division; telephone 718-354..., 2008 issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a...

  9. 77 FR 22489 - Special Anchorage Regulations, Newport Bay Harbor, CA

    Science.gov (United States)

    2012-04-16

    ... Anchorage Regulations, Newport Bay Harbor, CA'' in the Federal Register (76 FR 78185). We received no... businesses, not-for-profit organizations that are independently owned and operated and are not dominant in... aft moorings for recreational and small craft of such size and alignment as permitted by the...

  10. External post-tensioning of cfrp tendons using integrated sleeve-wedge anchorage

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Bennitz, Anders; Goltermann, Per;

    2012-01-01

    Strengthening of structures using external post-tension CFRP systems have proven to be anefficient method as such system increases the structural capacity and reduces cracks and deflection. Sufficient anchorage is of significant importance since the anchorage provides the connection between...... anchorage was obtained using the novel anchorage and that its behaviour is stable and predicatble when short term static load is applied. Desired strengthening was also observed in external post-tensioning on reinforced concrete T-beams. The requirements and definitions on a stable anchorage of CFRP tendons...

  11. Molar distalization with the assistance of Temporary Anchorage Devices.

    Science.gov (United States)

    Palencar, Adrian J

    2015-01-01

    This article describes efficient techniques for distalization of maxillary and mandibular molars with the assistance of Temporary Anchorage Devices (TADs). There are numerous occasions where the distalization of molars is required in lieu of the odontectomy of bicuspids. In the past, extra-oral force has been used, (i.e. Cervical or Combination Head Gear, or intra-oral force, i.e. Posterior Sagittal Appliance, Modified Greenfield Appliance, Williams DMJ 20001, CD Distalizer, Magill Sagittal, Pendulum Appliance, etc.). All the intra-oral appliances have a common denominator the orthodontic clinician has to deal with, the undesirable expression of the Third Law of Newton. The utilization of TADs allows us to circumvent this shortcoming, establishing an absolute anchorage, and thus completely negate the expression of the Third Law of Newton. PMID:25881377

  12. Virtual planning for vertical control using temporary anchorage devices

    OpenAIRE

    Mauricio Accorsi

    2015-01-01

    The new and innovative technologies are unprecedentedly improving the level of proficiency in orthodontics in the recent history of this area of expertise. The proliferation of advances, such as self-ligating systems, temporary anchorage devices, shape-memory wires, robotically wire bending, intraoral scanners, cone-beam computed tomography, bring the virtual planning, and confection of dental devices through CAD/CAM systems to the real world. In order to get efficiency and efficacy in orthod...

  13. Tensile tests of basalt FRP rebars using chemical anchorages

    OpenAIRE

    Neagoe, Catalin Andrei; Gil Espert, Lluís

    2013-01-01

    In the current report are analyzed the experimental results of initial tensile tests of Basalt FRP (BFRP) rebars provided by VSL. The investigation was conducted in the laboratory of CER LITEM. Objectives of the study: to determine the tensile strengths of 6 mm and 8 mm basalt FRP rebars, and to determine what type of test setup and anchorage system is best suited for future tensile tests of BFRP bars.

  14. Tensile tests of basalt FRP rebars using mechanical anchorages

    OpenAIRE

    Neagoe, Catalin Andrei; Gil Espert, Lluís

    2013-01-01

    In the current report are analyzed the experimental results of initial tensile tests of Basalt FRP (BFRP) rebars provided by VSL. The investigation was conducted on the 19th of February 2013, in the laboratory of CER LITEM. Objectives of the study: to determine the tensile strengths of 6 mm and 8 mm basalt FRP rebars, and to determine what type of test setup and anchorage system is best suited for future tensile tests of BFRP bars.

  15. Image guided placement of temporary anchorage devices for tooth movement

    International Nuclear Information System (INIS)

    The aim of this project is to develop an image guided protocol for placement of a temporary anchorage device without surgically reflecting a mucoperiosteal flap. Eighteen orthodontic cases were selected for skeletal anchorage from the department of orthodontics at Case University. CBCT images of the subjects were taken using the Hitachi CB MercuRay system set at 15 mA, 120 kVp. CBCT images evaluated the ideal location for TAD placement in three dimensions. Horizontal and vertical linear measurements were taken from fixed dental landmarks to clearly define the location for placement. Transverse slices were used to evaluate the thickness of the buccal plate. Using the transverse view, the angle of insertion was determined such that the maximum buccal plate surface area would contact the screw. TADs were placed in the optimum location, with the most appropriate angle of insertion using a closed approach and with minimal local anesthesia and without flap elevation. Results: All TADs were placed without anatomic encroachment and enabled fixed orthodontic anchorage. (orig.)

  16. Image guided placement of temporary anchorage devices for tooth movement

    Energy Technology Data Exchange (ETDEWEB)

    Bahl-Palomo, L.; Bissada, N. [Case Western Reserve Univ. School of Dental Medicine, Dept. of Periodontics, Cleveland, OH (United States); Palomo, J.M.; Hans, M.G. [Case Western Reserve Univ. School of Dental Medicine, Dept. of Orthodontics, Cleveland, OH (United States)

    2007-06-15

    The aim of this project is to develop an image guided protocol for placement of a temporary anchorage device without surgically reflecting a mucoperiosteal flap. Eighteen orthodontic cases were selected for skeletal anchorage from the department of orthodontics at Case University. CBCT images of the subjects were taken using the Hitachi CB MercuRay system set at 15 mA, 120 kVp. CBCT images evaluated the ideal location for TAD placement in three dimensions. Horizontal and vertical linear measurements were taken from fixed dental landmarks to clearly define the location for placement. Transverse slices were used to evaluate the thickness of the buccal plate. Using the transverse view, the angle of insertion was determined such that the maximum buccal plate surface area would contact the screw. TADs were placed in the optimum location, with the most appropriate angle of insertion using a closed approach and with minimal local anesthesia and without flap elevation. Results: All TADs were placed without anatomic encroachment and enabled fixed orthodontic anchorage. (orig.)

  17. Optimizing Anterior En Masse Retraction with Miniscrew Anchorage

    Directory of Open Access Journals (Sweden)

    Pavankumar Janardan Vibhute

    2011-01-01

    Full Text Available In severely protrusive patients, skeletal anchorage from miniscrew is often used to avoid anchorage loss with preferred miniscrew location near centre of resistance (Cres of posterior teeth. Biomechanical requirement for directing retraction force towards Cres of posterior teeth demands the insertion of miniscrew in loose mucosa, where risk of infection and failure increases. In addition, undesirable biomechanical side effects on anterior and posterior segments may be possible in all three planes, when continuous arch sliding mechanics are installed with miniscrew anchorage. This paper describes technique of molar-stabilizing power arm (MSPA for simultaneous intrusion and retraction of anteriors with miniscrew placement at attached gingiva between 1st molar and 2nd premolar. Advantages of this technique include (i the need of miniscrews placement in loose mucosa apically near the Cres of the posterior teeth is eliminated, (ii the risk of infection and miniscrew failure is lowered since the miniscrew is placed in attached gingiva rather than the loose mucosa, and (iii by adjusting vertical length or replacing MSPA, alteration of the retraction force vector is possible in all three planes; thus, need of removal and repositioning of the miniscrew (e.g., in correction of occlusal cant can be eliminated.

  18. Optimizing anterior en masse retraction with miniscrew anchorage.

    Science.gov (United States)

    Vibhute, Pavankumar Janardan

    2011-01-01

    In severely protrusive patients, skeletal anchorage from miniscrew is often used to avoid anchorage loss with preferred miniscrew location near centre of resistance (Cres) of posterior teeth. Biomechanical requirement for directing retraction force towards Cres of posterior teeth demands the insertion of miniscrew in loose mucosa, where risk of infection and failure increases. In addition, undesirable biomechanical side effects on anterior and posterior segments may be possible in all three planes, when continuous arch sliding mechanics are installed with miniscrew anchorage. This paper describes technique of molar-stabilizing power arm (MSPA) for simultaneous intrusion and retraction of anteriors with miniscrew placement at attached gingiva between 1st molar and 2nd premolar. Advantages of this technique include (i) the need of miniscrews placement in loose mucosa apically near the Cres of the posterior teeth is eliminated, (ii) the risk of infection and miniscrew failure is lowered since the miniscrew is placed in attached gingiva rather than the loose mucosa, and (iii) by adjusting vertical length or replacing MSPA, alteration of the retraction force vector is possible in all three planes; thus, need of removal and repositioning of the miniscrew (e.g., in correction of occlusal cant) can be eliminated. PMID:22567438

  19. CFRP Mechanical Anchorage for Externally Strengthened RC Beams under Flexure

    Science.gov (United States)

    Ali, Alnadher; Abdalla, Jamal; Hawileh, Rami; Galal, Khaled

    De-bonding of carbon fiber reinforced polymers (CFRP) sheets and plates from the concrete substrate is one of the major reasons behind premature failures of beams that are externally strengthened with such CFRP materials. To delay or prevent de-bonding and therefore enhancing the load carrying capacity of strengthened beams, several anchorage systems were developed and used. This paper investigates the use of CFRP mechanical anchorage of CFRP sheets and plates used to externally strengthen reinforced concrete beams under flexure. The pin-and-fan shape CFRP anchor, which is custom-made from typical rolled fiber sheets and bundles of loose fiber is used. Several reinforced concrete beams were casted and tested in standard four-point bending scheme to study the effectiveness of this anchorage system. The beams were externally strengthened in flexure with bonded CFRP sheets and plates and then fastened to the soffit of the beams' using various patterns of CFRP anchors. It is observed that the CFRP plates begins to separate from the beams as soon as de-bonding occurs in specimens without CFRP anchors, while in beams with CFRP anchors de-bonding was delayed leading to increase in the load carrying capacity over the un-anchored strengthened beams.

  20. Mini-Implants in the Anchorage Armamentarium: New Paradigms in the Orthodontics

    OpenAIRE

    Masaru Yamaguchi; Toshihiro Inami; Ko Ito; Kazutaka Kasai; Yasuhiro Tanimoto

    2012-01-01

    Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD). These devices are small, are implanted with a relatively simple surgical procedure, and increase the potential for better orthodontic results. Therefore, mi...

  1. Comparative photoelastic study of dental and skeletal anchorages in the canine retraction

    Directory of Open Access Journals (Sweden)

    Cristiane Aparecida de Assis Claro

    2014-01-01

    Full Text Available OBJECTIVE: To compare dental and skeletal anchorages in mandibular canine retraction by means of a stress distribution analysis. METHODS: A photoelastic model was produced from second molar to canine, without the first premolar, and mandibular canine retraction was simulated by a rubber band tied to two types of anchorage: dental anchorage, in the first molar attached to adjacent teeth, and skeletal anchorage with a hook simulating the mini-implant. The forces were applied 10 times and observed in a circular polariscope. The stresses located in the mandibular canine were recorded in 7 regions. The Mann-Whitney test was employed to compare the stress in each region and between both anchorage systems. The stresses in the mandibular canine periradicular regions were compared by the Kruskal-Wallis test. RESULTS: Stresses were similar in the cervical region and the middle third. In the apical third, the stresses associated with skeletal anchorage were higher than the stresses associated with dental anchorage. The results of the Kruskal-Wallis test showed that the highest stresses were identified in the cervical-distal, apical-distal, and apex regions with the use of dental anchorage, and in the apical-distal, apical-mesial, cervical-distal, and apex regions with the use of skeletal anchorage. CONCLUSIONS: The use of skeletal anchorage in canine retraction caused greater stress in the apical third than the use of dental anchorage, which indicates an intrusive component resulting from the direction of the force due to the position of the mini-implant and the bracket hook of the canine.

  2. 49 CFR 571.225 - Standard No. 225; Child restraint anchorage systems.

    Science.gov (United States)

    2010-10-01

    ...) and (b) of S7 apply to the test procedures in S8. (a) Vehicle seats are adjusted to their full... systems. S1. Purpose and scope. This standard establishes requirements for child restraint anchorage... buses, and funeral coaches. S3. Definitions. Child restraint anchorage means any vehicle...

  3. 77 FR 8252 - Adequacy Status of the Anchorage, Alaska, Carbon Monoxide Maintenance Plan for Transportation...

    Science.gov (United States)

    2012-02-14

    ... existing violations, or delay timely attainment of the national ambient air quality standards. The minimum... AGENCY Adequacy Status of the Anchorage, Alaska, Carbon Monoxide Maintenance Plan for Transportation... budget (MVEB) in the Anchorage, Alaska, Carbon Monoxide (CO) Maintenance Plan, submitted by the State...

  4. Flexural Strengthening of RC Slabs with Prestressed CFRP Strips Using Different Anchorage Systems

    Directory of Open Access Journals (Sweden)

    José Sena-Cruz

    2015-10-01

    Full Text Available Externally Bonded Reinforcement (EBR technique has been widely used for flexural strengthening of concrete structures by using carbon fiber-reinforced polymers (CFRP. EBR technique offers several structural advantages when the CFRP material is prestressed. This paper presents an experimental and numerical study on reinforced (RC slabs strengthened in flexure with prestressed CFRP strips as a structural strengthening system. The strips are applied as an externally bonded reinforcement (EBR and anchored with either a mechanical or a gradient anchorage. The former foresees metallic anchorage plates fixed to the concrete substrate, while the latter is based on an accelerated epoxy resin curing followed by a segment-wise prestress force decrease at the strip ends. Both anchorage systems, in combination with different CFRP strip geometries, were subjected to static loading tests. It could be demonstrated that the composite strip’s performance is better exploited when prestressing is used, with slightly higher overall load carrying capacities for mechanical anchorages than for the gradient anchorage. The performed investigations by means of a cross-section analysis supported the experimental observation that in case a mechanical anchorage is used, progressive strip debonding changes the fully bonded configuration to an unbonded end-anchored system. The inclusion of defined debonding criteria for both the anchorage zones and free length between the anchorage regions allowed to precisely capture the ultimate loading forces.

  5. 78 FR 11097 - Artificial Island Anchorage No. 2 Partial Closure, Delaware River; Salem, NJ

    Science.gov (United States)

    2013-02-15

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Artificial Island Anchorage No. 2 Partial Closure... for the safety of life on the navigable waters of the Artificial Island Anchorage. This closure is.... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM...

  6. Mini-Implants in the Anchorage Armamentarium: New Paradigms in the Orthodontics

    Directory of Open Access Journals (Sweden)

    Masaru Yamaguchi

    2012-01-01

    Full Text Available Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD. These devices are small, are implanted with a relatively simple surgical procedure, and increase the potential for better orthodontic results. Therefore, miniscrews not only free orthodontists from anchorage-demanding cases, but they also enable clinicians to have good control over tooth movement in 3 dimensions. The miniplate type also produces significant improvements in treatment outcomes and has widened the spectrum of orthodontics. The purpose of this paper is to update clinicians on the current concepts and versatile uses and clinical applications of skeletal anchorage in orthodontics.

  7. Treatment of a Class II deepbite with microimplant anchorage.

    Science.gov (United States)

    Park, Hyo-Sang; Kim, Ji-Yeun; Kwon, Tae-Geon

    2011-03-01

    The goal of this report was to illustrate new treatment mechanics for using microimplants for the treatment of a Class II Division 2 deepbite malocclusion. A 29-year-old woman with a deepbite was treated with the aid of microimplant anchorage. Microimplants placed between the maxillary second premolars and first molars were used as anchorage to apply a distal force to the anterior teeth to correct the Class II canine and molar relationships. A distal force was applied to long hooks that were crimped between the lateral incisors and the canines. By applying a backward force to the long hooks, the maxillary anterior teeth experienced palatal root movement with no change in the vertical and anteroposterior positions of the incisal edges. The distal extrusive movement of the maxillary second molars achieved by disengaging the second molars from the archwire during distal force application and an anterior bite-block bonded on the lingual surface of the maxillary central incisors produced the increase in vertical dimension. The distal force to the long extended hooks from the microimplants was possibly good mechanics for obtaining the palatal root movement and correcting the Class II canine and molar relationships. The anterior bite-block and disengagement of the maxillary second molars during distal force application were effective for increasing the vertical dimension.

  8. 1964 Great Alaska Earthquake: a photographic tour of Anchorage, Alaska

    Science.gov (United States)

    Thoms, Evan E.; Haeussler, Peter J.; Anderson, Rebecca D.; McGimsey, Robert G.

    2014-01-01

    On March 27, 1964, at 5:36 p.m., a magnitude 9.2 earthquake, the largest recorded earthquake in U.S. history, struck southcentral Alaska (fig. 1). The Great Alaska Earthquake (also known as the Good Friday Earthquake) occurred at a pivotal time in the history of earth science, and helped lead to the acceptance of plate tectonic theory (Cox, 1973; Brocher and others, 2014). All large subduction zone earthquakes are understood through insights learned from the 1964 event, and observations and interpretations of the earthquake have influenced the design of infrastructure and seismic monitoring systems now in place. The earthquake caused extensive damage across the State, and triggered local tsunamis that devastated the Alaskan towns of Whittier, Valdez, and Seward. In Anchorage, the main cause of damage was ground shaking, which lasted approximately 4.5 minutes. Many buildings could not withstand this motion and were damaged or collapsed even though their foundations remained intact. More significantly, ground shaking triggered a number of landslides along coastal and drainage valley bluffs underlain by the Bootlegger Cove Formation, a composite of facies containing variably mixed gravel, sand, silt, and clay which were deposited over much of upper Cook Inlet during the Late Pleistocene (Ulery and others, 1983). Cyclic (or strain) softening of the more sensitive clay facies caused overlying blocks of soil to slide sideways along surfaces dipping by only a few degrees. This guide is the document version of an interactive web map that was created as part of the commemoration events for the 50th anniversary of the 1964 Great Alaska Earthquake. It is accessible at the U.S. Geological Survey (USGS) Alaska Science Center website: http://alaska.usgs.gov/announcements/news/1964Earthquake/. The website features a map display with suggested tour stops in Anchorage, historical photographs taken shortly after the earthquake, repeat photography of selected sites, scanned documents

  9. Analysis on Bearing Capacity of Tunnel-Type Anchorage of a Long-Span Suspension Bridge

    Institute of Scientific and Technical Information of China (English)

    Zhu Yu; Wei Jun; Yang Manjuan; Li Hao; Liu Hongqing

    2005-01-01

    Due to complicated rock structure and environment, a prototype test for a tunnel-type anchorage is infeasible. Based on the rock mass parameters from tests, a three-dimensional (3D) elasto-plastic analysis was performed to simulate the influence of the construction procedure of Siduhe bridge with tunnel-type anchorage (TTA) in Hubei Province, China. The surrounding rock and concrete anchorage body were simulated by 8 nodes 3D brick elements. The geostatic state of the complex geometric structure was established with initial data. The in-situ concrete casting of the anchorage body and excavation of the rock mass were simulated by tetrahedral shell elements. The results show that the surrounding rock is in an elastic state under the designed cable force. The numerical overloading analysis indicates that the capacity of the surrounding anchorage is 7 times that of the designed cable force. The failure pattern shows that two anchorage bodies would be pulled out in the end. The maximum shear stress appears 10 m before the back anchorage face. The maximum range influenced by the TTA under ultimate loads is about 16 m.

  10. Exterior beam-column joint study with non-conventional reinforcement detailing using mechanical anchorage under reversal loading

    Indian Academy of Sciences (India)

    S Rajagopal; S Prabavathy

    2014-10-01

    Reinforced concrete structures beam-column joints are the most critical regions in seismic prone areas. Proper reinforcement anchorage is essential to enhance the performance of the joints. An attempt has been made to appraise the performance of the anchorages and joints. The anchorages are detailed as per ACI-352 (mechanical anchorages), ACI-318 (conventional bent hooks) and IS-456 (conventional full anchorage). The joints are detailed without confinement in group-I and with additional X-cross bar in group-II. To assess the seismic performance, the specimens are assembled into two groups of three specimens each and were tested under reversal loading, The specimen with T-type mechanical anchorage (Headed bar) and T-type mechanical anchorage combination with X-cross bar exhibited significant improvement in seismic performance: load-displacement capacity, displacement ductility, stiffness degradation, controlled crack capacity in the joint shear panel and also reduced congestion of reinforcement in joint core.

  11. Intrusion of overerupted molars by corticotomy and orthodontic skeletal anchorage.

    Science.gov (United States)

    Moon, Cheol-Hyun; Wee, Jin-Uk; Lee, Hyun-Sun

    2007-11-01

    This article describes the orthodontic treatment of a 26-year-old female patient with overerupted left maxillary molar teeth. Her chief complaint was that the maxillary left first and the second molar intruded into the space required for the mandibular left first and the second molars, preventing prosthodontic treatment. The authors performed a corticotomy and used orthodontic skeletal anchorage with a miniplate and orthodontic miniscrews with a head modified to provide a specially designed hook. With this approach, they were able to achieve a sufficient amount of molar intrusion without discomfort, root resorption, or extrusion of the adjacent teeth. The first molar was intruded 3.0 mm and second molar was intruded 3.5 mm during 2 months of treatment. These results have been maintained for 11 months. PMID:18004918

  12. Numerical Analysis of Quality Inspection of Anchorage System

    Institute of Scientific and Technical Information of China (English)

    ZHANGYongxing; XUMing

    2002-01-01

    Sonoprobe method has been applied in non-destructive inspection of anchorage project.The fundament is that dynamic transient excitation causes the elastic vibration of an anchor bar,and flaws can be estimated or deduced by determining transient response of the anchor bar.FEA numeric solution of hyperbolic equation indicates that deductions must comply with acoustic parameters such as velocity of sound,vibration range,wave shape etc when inspecting interior flaws in the grout of an anchor bar,Based on wavelet packet analysis,the energy eigenvector is a flaw vector,which could be regarded as the basis in the nondestructive inspection of anchors,As a non-linear dynamical system,artifical neural networks dealing with quality insection of gray system have been proved efficient.

  13. Finite element simulation and testing of ISW CFRP anchorage

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Goltermann, Per; Hertz, Kristian Dahl

    2013-01-01

    Several Carbon Fibre Reinforced Polymers (CFRP) systems have been used successfully for strengthening of structures during the last decades. However, the fracture often occurs in the concrete adherent or in the adhesive interface when used for steel strengthening. As a consequence the CFRP...... to the remaining structure. However, reaching the full capacity of the CFRP material is difficult since anchoring often courses premature failure modes such as crushing of the Fibre Reinforced Polymers (FRP), slip in the FRP and adjacent adherent, cutting of the fibres, bending of fibres and frontal overload...... is modelled in the 3D finite Element program ABAQUS, just as digital image correlation (DIC) testing was performed to verify the finite element simulation. Also a new optimized design was produced to ensure that the finite element simulation and anchorage behaviour correlated well. It is seen...

  14. Anchorage Failure of RC beams strengthened with FRP at the bottom face

    DEFF Research Database (Denmark)

    Täljsten, Björn; Arifovic, Fedja

    2009-01-01

    When RC beams are strengthened by FRP plates bonded to the bottom face of the beam they fail due to the lack of the mechanical anchorage of the plate. This paper shows that it is possible to relate the anchorage failure of tension face FRP-plated beams to the crack sliding capacity of the beams...... load of tension face plated beams. The assumption is that the FRP-plate must be extended at least one critical anchorage length beyond the theoretical occurrence of the critical diagonal crack....

  15. Urban contaminants project: Data for sediment, fish and eggs collected from Chester Creek, Anchorage, Alaska 1991

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Urbanization has degraded the water quality and adversely impacted biological communities in the lakes and streams of Anchorage. Pollution from point and nonpoint...

  16. CFRP筋复合型锚具锚固性能研究%Research on Anchorage Performance of Wedge-bond Anchorage for CFRP Tendons

    Institute of Scientific and Technical Information of China (English)

    刘荣桂; 刘德鑫; 延永东

    2013-01-01

    In order to solve the anchorage problems for carbon fiber reinforced polymer (CFRP) tendons,a wedge-bond anchorage for CFRP tendons was developed.This anchorage consisted of bonding material,metal sleeve,clip and conical barrel.Influence factors of anchorage performance,such as length of clip,length of metal sleeve,clip clamping position and bonding material were illustrated.Results show that bonding material,length of metal sleeve,and clip clamping position will have significant influence on anchorage performance.The clip clamping position should be avoided at both ends of the metal sleeve,and should make compression zone metal sleeve length be less than that of the tension zone length.Meanwhile,the anchorage performance of bonding material Lica-B is better than that of bonding material Lica-A.The each component of wedge-bond anchorage has good cooperative work performance,and there is no relative slip between clip and metal sleeve.The wedge-bond anchorage with reasonable parameters can anchor CFRP tendons with diameter of 8 mm effectively.%为解决碳纤维增强复合材料(CFRP)筋的锚固问题,研制了由粘结材料、金属筒、夹片和锚环组成的CFRP筋复合型锚具,并进行了夹片长度、金属筒长度、夹片夹持位置以及粘结材料对CFRP筋复合型锚具的锚固性能影响试验.结果表明:粘结材料、金属筒长度和夹片夹持位置均对锚固性能有较大影响;夹片的夹持位置应避免在金属筒两端,且宜使金属筒受压区长度小于受拉区长度;Lica-B型粘结材料锚固性能优于Lica-A型粘结材料;复合型锚具各组件协同工作性能良好,夹片与金属筒间无滑移产生;参数合理的该类复合型锚具可有效锚固直径为8 mm的CFRP筋.

  17. Mechanical properties and failure characteristics of fractured sandstone with grouting and anchorage

    Institute of Scientific and Technical Information of China (English)

    Zong Yijiang; Han Lijun; Qu Tao; Yang Shengqi

    2014-01-01

    Based on uniaxial compression experimental results on fractured sandstone with grouting and anchorage, we studied the strength and deformation properties, the failure model, crack formation and evolution laws of fractured sandstone under different conditions of anchorage. The experimental results show that the strength and elastic modulus of fractured sandstone with different fracture angles are sig-nificantly lower than those of intact sandstone. Compared with the fractured samples without anchorage, the peak strength, residual strength, peak and ultimate axial strain of fractured sandstone under different anchorage increase by 64.5-320.0%, 62.8-493.0%, and 31.6-181.4%, respectively. The number of bolts and degree of pre-stress has certain effects on the peak strength and failure model of fractured sandstone. The peak strength of fractured sandstone under different anchorage increases to some extent, and the failure model of fractured sandstone also transforms from tensile failure to tensile-shear mixed failure with the number of bolts. The pre-stress can restrain the formation and evolution process of tensile cracks, delay the failure process of fractured sandstone under anchorage and impel the transformation of failure model from brittle failure to plastic failure.

  18. Transfer and anchorage bond behaviour in self-compacting concrete

    Directory of Open Access Journals (Sweden)

    Rigueira-Víctor, J. W.

    2006-12-01

    Full Text Available Self-compacting concretes (SCC provide solutions to the problems facing precast concrete construction, enhancing competitiveness, reducing turnaround times and improving final product quality. SCC is fast becoming a key product for the future development of the precast pre-stressed concrete industry.The present paper compares the bond performance of SCC and traditional concrete (TC. The bond performance results confirm the viability of SCC in precast pre-stressed concrete manufacture, despite a slightly higher loss of pre-stressing force and slightly greater anchorage lengths in SCC with a low water/cement ratio. No differences in transfer or anchorage length were detected,however, when high strength TC and SCC were compared. The ECADA test method proved to be well suited to detecting the differences between the concretes analyzed.El desarrollo de los hormigones autocompactantes (SCCofrece muchas posibilidades a las construcciones con hormigón prefabricado, aumentando su competitividad, reduciéndolos plazos de fabricación y ofreciendo mejoras en la calidad del producto final. El SCC se está convirtiendo en un producto clave para el futuro desarrollo de la industria de prefabricados de hormigón pretensado.En este estudio se compara el comportamiento adherente de los SCC con el de los hormigones tradicionales (TC actuales. Los resultados obtenidos confirman la viabilidad del uso de los SCC para la fabricación de elementos prefabricados con hormigón pretensado, en lo relativo a su comportamiento adherente, aunque con la necesidad de considerar unas pérdidas de pretensado ligeramente mayores. Asimismo,debe esperarse un ligero aumento de las longitudes de anclaje cuando se trabaje con SCC de baja relación agua/cemento. Sin embargo, no se han detectado diferencias de comportamiento entre ambos tipos de hormigón cuando la resistencia a compresión es alta en lo relativo a las longitudes de transmisión y anclaje. El método de ensayo ECADA

  19. Virtual planning for vertical control using temporary anchorage devices

    Directory of Open Access Journals (Sweden)

    Mauricio Accorsi

    2015-01-01

    Full Text Available The new and innovative technologies are unprecedentedly improving the level of proficiency in orthodontics in the recent history of this area of expertise. The proliferation of advances, such as self-ligating systems, temporary anchorage devices, shape-memory wires, robotically wire bending, intraoral scanners, cone-beam computed tomography, bring the virtual planning, and confection of dental devices through CAD/CAM systems to the real world. In order to get efficiency and efficacy in orthodontics with these new technologies, we must understand the importance of systemically managed clinical information, medical, and dentistry history of the patients, including the images resources, which ensures the use of a communication that is assisted by the technology, with an interdisciplinary team so that the database is able to help and support the process of therapeutic decision-making. This paper presents the clinical case of a borderline patient for orthognathic surgery who had his final treatment planning supported by these new tools for three-dimensional diagnosis and virtual planning.

  20. Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells

    OpenAIRE

    Chia Chu; Donald P Bottaro; Betenbaugh, Michael J.; Joseph Shiloach

    2016-01-01

    The epithelial-mesenchymal transition (EMT) is a complex cancer progression that can boost the metastatic potential of transformed cells by inducing migration, loss of cell adhesion, and promoting proliferation under anchorage-independent conditions. A DNA microarray analysis was performed comparing parental anchorage-dependent MDCK cells and anchorage-independent MDCK cells that were engineered to express human siat7e (ST6GALNAC5). The comparison identified several genes involved in the EMT ...

  1. Guidelines for evaluation of anchorage adequacy for safety-related equipment typically used on WWER-type NPPs

    International Nuclear Information System (INIS)

    This report describes the criteria which should be met when the capacity evaluation of anchorage of safety related equipment is performed for the WWER type NPPs. It should be noted that these criteria were developed specifically for anchorage of WWER type equipment and components to the concrete or steel building structures and they cover different types of anchor bolts and other anchorage details which are typical just for the existing, constructed or reconstructed WWER type NPPs. The screening approach for verifying of equipment anchorage presented in this report is based on a combination of inspections, calculations, and engineering judgement

  2. Experiment on Anchorage Performance of Bond-type Anchorage for CFRP Tendon%CFRP筋粘结式锚具锚固性能试验

    Institute of Scientific and Technical Information of China (English)

    蒋田勇; 方志

    2011-01-01

    针对碳纤维增强塑料(CFRP)作为预应力筋或拉索时出现的锚固问题,开发了一种以活性粉末混凝土(RPC)作为粘结介质的粘结式锚具.建立了平均粘结强度及其对应的滑移量、临界锚固长度以及粘结滑移本构模型等计算公式.通过静载试验研究了筋材表面形状、锚固长度、根数、间距、套筒内壁倾角以及筋材预张拉等对锚固性能的影响.结果表明:CFRP筋的表面形状对以RPC作为粘结介质的粘结式锚具的锚固性能有着决定性影响;当表面压纹CFRP筋的抗拉强度不大于3 000 MPa,RPC抗压强度不小于130 MPa时,对于普通粘结试件,临界锚团长度为20倍筋材直径;对于预张拉粘结试件,当预张比为56%时,锚固系统具有最短的临界锚固长度为13倍筋材直径;多筋同时锚固时,其间距不宜小于1倍筋材直径.%Aimed at anchorage problems that carbon fiber reinforced polymer/plastics (CFRP)was used as prestress tendon and cable reactive powder concrete (RPC) was regarded as bond medium and based on it, a new bond-type anchorage was developed.The calculated formulas of average bond strength and its corresponding slip, critical anchorage length, and bond-slip constitutive model were proposed.Influences of surface shape, bond length, number and space of CFRP tendons, slope angle of inner wall of steel sleeve and pretensioning load on anchorage performance were studied by static test.Test results show that the surface shape of CFRP tendon is significant to the anchorage performance of the bond-type anchorage.When the tensile strength of the indented surface CFRP tendon is less than 3 000 MPa and compressive strength of RPC is more than 130 MPa, the critical anchorage length is 20 diameters of general CFRP tendon for common bond specimen, the shortest critical anchorage length in anchorage system is 13 diameters of pretensioning CFRP tendon with ratio of 56 % of pretensioning load.The appropriate rod space is

  3. Bolt Pull-Out Tests of Anchorage Body under Different Loading Rates

    Directory of Open Access Journals (Sweden)

    Tong-bin Zhao

    2015-01-01

    Full Text Available Based on the force analysis and mechanical transmission mechanism of grouting bolts, the self-developed test apparatus for interfacial mechanics is used to study the distribution rule of axial force and interfacial stress of bolts in anchorage body. At the same time, pull-out tests of anchorage body are simulated with the particle flow code software PFC2D, and stress distribution and failure patters are researched under different loading rates. The results show that the distribution of axial force and interfacial shear stress is nonuniform along the anchorage section: axial force decreases, shear force increases first and then decreases, and the maximum value of both of them is closed to the pull-out side; with the increase of loading rates, both of axial force and interfacial shear stress show a trend of increase in the upper anchorage section but changes are not obvious in the lower anchorage section, which causes serious stress concentration; failure strength of pull-out and loading rates show a linear correlation; according to loading rates’ impact on the anchoring effect, the loading rates’ scope can be divided into soft scope (v100 mm/s.

  4. The Influence of CFRP Anchorage on Achieving Sectional Flexural Capacity of Strengthened Concrete Beams

    Directory of Open Access Journals (Sweden)

    Hayder A. Rasheed

    2015-12-01

    Full Text Available This research program is intended to verify the influence of using distributed external U-wrap CFRP anchorage to shift the failure mode from overall debonding to sectional flexural failure for concrete beams externally bonded with CFRP sheets. Premature cover delamination and FRP debonding are predominant failure modes in FRP flexural strengthening that may be delayed or prevented by using FRP anchorage. The present experimental study aims to comparatively prove that proper anchorage of flexural strengthening is anticipated to yield a classical flexural failure by FRP rupture or concrete crushing. Once the cohesion of concrete and/or the adhesion with the FRP is exhausted, the U-wraps are engaged to provide anchorage to the flexural FRP through shear friction. Accordingly, three identical T beams and three identical rectangular beams were designed and constructed to examine the capacity improvement by preventing premature debonding failure. The first specimen in each series was tested as a control beam. The second specimen in each series was strengthened using five layers of flexural CFRP in order to admit a debonding failure. The third specimen in each series was strengthened with the same five layers of flexural CFRP plus additional transverse CFRP U-wraps. This study proved that it is possible to quantify the higher flexural capacity of CFRP strengthened beams using external anchorage.

  5. Experimental study and stress analysis of rock bolt anchorage performance

    Directory of Open Access Journals (Sweden)

    Yu Chen

    2014-10-01

    Full Text Available A new method was developed to apply pull-and-shear loads to the bolt specimen in order to evaluate the anchorage performance of the rebar bolt and the D-Bolt. In the tests, five displacing angles (0°, 20°, 40°, 60°, and 90°, two joint gaps (0 mm and 30 mm, and three kinds of host rock materials (weak concrete, strong concrete, and concrete-granite were considered, and stress–strain measurements were conducted. Results show that the ultimate loads of both the D-Bolt and the rebar bolt remained constant with any displacing angles. The ultimate displacement of the D-Bolt changed from 140 mm at the 0° displacing angle (pure pull to approximately 70 mm at a displacing angle greater than 40°. The displacement capacity of the D-Bolt is approximately 3.5 times that of the rebar bolt under pure pull and 50% higher than that of the rebar bolt under pure shear. The compressive stress exists at 50 mm from the bolt head, and the maximum bending moment value rises with the increasing displacing angle. The rebar bolt mobilises greater applied load than the D-Bolt when subjected to the maximum bending. The yielding length (at 0° of the D-Bolt is longer than that of the rebar bolt. The displacement capacity of the bolts increased with the joint gap. The bolt subjected to joint gap effect yields more quickly with greater bending moment and smaller applied load. The displacement capacities of the D-Bolt and the rebar bolt are greater in the weak host rock than that in the hard host rock. In pure shear condition, the ultimate load of the bolts slightly decreases in the hard rock. The yielding speed in the hard rock is higher than that in the weak rock.

  6. Experimental study and stress analysis of rock bolt anchorage performance

    Institute of Scientific and Technical Information of China (English)

    Yu Chen

    2014-01-01

    A new method was developed to apply pull-and-shear loads to the bolt specimen in order to evaluate the anchorage performance of the rebar bolt and the D-Bolt. In the tests, five displacing angles (0?, 20?, 40?, 60?, and 90?), two joint gaps (0 mm and 30 mm), and three kinds of host rock materials (weak concrete, strong concrete, and concrete-granite) were considered, and stressestrain measurements were con-ducted. Results show that the ultimate loads of both the D-Bolt and the rebar bolt remained constant with any displacing angles. The ultimate displacement of the D-Bolt changed from 140 mm at the 0? displacing angle (pure pull) to approximately 70 mm at a displacing angle greater than 40?. The displacement capacity of the D-Bolt is approximately 3.5 times that of the rebar bolt under pure pull and 50%higher than that of the rebar bolt under pure shear. The compressive stress exists at 50 mm from the bolt head, and the maximum bending moment value rises with the increasing displacing angle. The rebar bolt mobilises greater applied load than the D-Bolt when subjected to the maximum bending. The yielding length (at 0?) of the D-Bolt is longer than that of the rebar bolt. The displacement capacity of the bolts increased with the joint gap. The bolt subjected to joint gap effect yields more quickly with greater bending moment and smaller applied load. The displacement capacities of the D-Bolt and the rebar bolt are greater in the weak host rock than that in the hard host rock. In pure shear condition, the ultimate load of the bolts slightly decreases in the hard rock. The yielding speed in the hard rock is higher than that in the weak rock.

  7. Ground Water in the Anchorage Area, Alaska--Meeting the Challenges of Ground-Water Sustainability

    Science.gov (United States)

    Moran, Edward H.; Galloway, Devin L.

    2006-01-01

    Ground water is an important component of Anchorage's water supply. During the 1970s and early 80s when ground water extracted from aquifers near Ship Creek was the principal source of supply, area-wide declines in ground-water levels resulted in near record low streamflows in Ship Creek. Since the importation of Eklutna Lake water in the late 1980s, ground-water use has been reduced and ground water has contributed 14-30 percent of the annual supply. As Anchorage grows, given the current constraints on the Eklutna Lake water availability, the increasing demand for water could place an increasing reliance on local ground-water resources. The sustainability of Anchorage's ground-water resources challenges stakeholders to develop a comprehensive water-resources management strategy.

  8. Numerical Simulation and Experimental Validation of an Integrated Sleeve-Wedge Anchorage for CFRP Rods

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Smith, Scott T.; Täljsten, Björn;

    2011-01-01

    The tensioning of carbon fibre-reinforced polymer (CFRP) rods for prestressed concrete applications or post-tensioning repair and strengthening has met with mixed success. This is primarily due to limitations inherent in the use of traditional wedge anchors typically used for steel tendons....... Recently, an integrated sleeve-wedge anchorage has been successfully developed specifically for CFRP rods. This paper in turn presents a numerical simulation of the newly developed anchorage using ABAQUS. The three-dimensional finite element (FE) model, which considers material non-linearity, uses...... hexagonal elements for the barrel and CFRP rod and tetrahedral elements for the integrated sleeve-wedge. The simulated barrel surface strains are shown to compare well with optically measured strains, however, the numerical results are shown to be sensitive to the mechanical properties of the anchorage...

  9. 33 CFR 165.556 - Regulated Navigation Area; Chesapeake and Delaware Canal, Chesapeake City Anchorage Basin, MD.

    Science.gov (United States)

    2010-07-01

    ... areas, found in 33 CFR 165.13, apply to the regulated navigation area described in paragraph (a) of this...; Chesapeake and Delaware Canal, Chesapeake City Anchorage Basin, MD. 165.556 Section 165.556 Navigation and..., Chesapeake City Anchorage Basin, MD. (a) Location. The following area is a regulated navigation area:...

  10. Thick-Walled Cylinder Theory Applied on a Conical Wedge Anchorage

    DEFF Research Database (Denmark)

    Bennitz, Anders; Grip, Niklas; Schmidt, Jacob Wittrup

    2011-01-01

    for further development of the anchorage.In this paper, we derive and examine an analytical model for the internal stresses and strains within the anchorage for a prescribed presetting distance. This model is derived from the theory of thick walled cylinders under the assumptions regarding plane stress......-symmetric and 3D FE (Finite Element) models. Analytical and FE axi-symmetric models show good correspondence, though compared to the 3D FE model, they show a clear difference in the predicted radial stress distribution on the FRP. Thus, the derived analytical model can be a useful and faster alternative to FE...

  11. STUDY ON CHARACTERISTICS OF RESIDUAL STRENGTH OF RC BEAMS WITH DEFECTIVE ANCHORAGES DUE TO CORROSION OF REINFORCEMENTS

    Science.gov (United States)

    Murakami, Yuki; Dong, Wei; Oshita, Hideki; Suzuki, Shuichi; Tsutsumi, Tomoaki

    In this study, to evaluate flexural strength and shear strength with def ective anchorages due to corrosion of reinforcemen t, the bending test of the RC beams r eceived damage in the anchorage region due to corrosion was carried out. As a result, it is se ems that the residual shear strength of RC beams with defective anchorages depends on shear span ratio in addition to the anchorage performance. Furthermore, the authors propose an evaluation model for an shear strength of RC beams with defective anchorages on the basis of these experimental results and analy tical result. The value of residual shear strength calculated using this model corresponds to the test results in the past.

  12. Characterization of ambient fine particles in the northwestern area and Anchorage, Alaska.

    Science.gov (United States)

    Kim, Eugene; Hopke, Philip K

    2008-10-01

    Ambient PM2.5 (particulate matter less than 2.5 microm in aerodynamic diameter) in the northwestern United States and Alaska is dominated by carbonaceous compounds associated with wood burning and transportation sources. PM2.5 source characterization studies analyzing recent PM2.5 speciation data have not been previously reported for these areas. In this study, ambient PM2.5 speciation samples collected at two monitoring sites located in the northwestern area, Olympic Peninsula, WA, and Portland, OR, and one monitoring site located in Anchorage, AK, were characterized through source apportionments. Gasoline vehicle, secondary sulfate, and wood smoke were the largest sources of PM2.5 collected at the Anchorage, Olympic, and Portland monitoring sites, respectively. Secondary sulfates showed an April peak at Anchorage and a November peak at Portland that are likely related to the increased photochemical reaction and long-range transport in Anchorage and meteorological stagnation in Portland. Secondary nitrate at the Olympic site showed a weak summer high peak that could be caused by seasonal tourism in the national park. Backward trajectories suggested that the elevated aged sea salt concentrations at the Portland monitoring site could be regional transport of sea salt that passed through other contaminated air sheds along the coast. Oil combustion emissions that might originate from ships and ferries were observed at the Olympic monitoring site. PMID:18939780

  13. 75 FR 23804 - Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK...

    Science.gov (United States)

    2010-05-04

    ... National Park Service Notice of Inventory Completion: Alaska State Office, Bureau of Land Management... completion of an inventory of human remains and associated funerary objects in the control of the U.S. Department of the Interior, Bureau of Land Management, Alaska State Office, Anchorage, AK, and in...

  14. 77 FR 5743 - Special Anchorage Areas; Port of New York, NY

    Science.gov (United States)

    2012-02-06

    ..., 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public... northern and southern special anchorage areas in Sheepshead Bay, NY; and reducing the illegal mooring of... transit of chartered fishing boats to and from their NYC-managed piers to the west. Since moored...

  15. Biofilm formation on surface characterized micro-implants for skeletal anchorage in orthodontics

    NARCIS (Netherlands)

    Chin, Yeen; Sandham, John; de Vries, Jacob; van der Mei, Henderina; Busscher, Hendrik

    2007-01-01

    Micro-implants are increasingly popular in clinical orthodontics to effect skeletal anchorage. However, biofilm formation on their surfaces and subsequent infection of peri-implant tissues can result in either exfoliation or surgical removal of these devices. The present study aimed to assess biofil

  16. 33 CFR 166.200 - Shipping safety fairways and anchorage areas, Gulf of Mexico.

    Science.gov (United States)

    2010-07-01

    ... Navigation or danger markings must be installed as required by 33 CFR Subchapter C. (c) Special Conditions...: For Federal Register citations affecting § 166.200, see the List of CFR Sections Affected, which... anchorage areas, Gulf of Mexico. 166.200 Section 166.200 Navigation and Navigable Waters COAST...

  17. Oxidative Stress Modulates DNA Methylation during Melanocyte Anchorage Blockade Associated with Malignant Transformation

    Directory of Open Access Journals (Sweden)

    Ana C.E. Campos

    2007-12-01

    Full Text Available Both oxidative/nitrosative stress and alterations in DNA methylation are observed during carcinogenesis of different tumor types, but no clear correlation between these events has been demonstrated until now. Melanoma cell lines were previously established after submitting the nontumorigenic melanocyte lineage, melan-a, to cycles of anchorage blockade. In this work, increased intracellular oxidative species and nitric oxide levels, as well as alterations in the DNA methylation, were observed after melan-a detachment, which were also associated with a decrease in intracellular homocysteine (Hey, an element in the methionine (universal methyl donor cycle. This alteration was accompanied by increase in glutathione (GSH levels and methylated DNA content. Furthermore, a significant increase in dnmti and 3b expression was identified along melan-a anchorage blockade. LG-Nitro-L-arginine methyl esther (L-NAME, known as a nitric oxide synthase (NOS inhibitor, and N-acetyl-L-cysteine (NAC prevented the increase in global DNA methylation, as well as the increase in dnmti and 3b expression, observed during melan-a detachment. Interestingly, both L-NAME and NAC did not inhibit nitric oxide (NO production in these cells, but abrogated superoxide anion production during anchorage blockade. In conclusion, oxidative stress observed during melanocyte anchorage blockade seems to modulate DNA methylation levels and may directly contribute to the acquisition of an anoikis-resistant phenotype through an epigenetic mechanism.

  18. Extraction treatment of an adult patient with severe bimaxillary dentoalveolar protrusion using microscrew anchorage

    Institute of Scientific and Technical Information of China (English)

    OUYANG Li; ZHOU Yan-heng; FU Min-kui; DING Peng

    2007-01-01

    @@ Bimaxillary dentoalveolar protrusion is one of the most prevalent malocclusion in Asian population,1 Traditionally, orthodontic treatment often involves the extraction of four first premolars2 and demands the least amount of anchorage loss, therefore headgear used to be an unavoid- able fate of these patients.

  19. The benefit of differential moment concept in managing posterior anchorage and avoiding bite deepening

    Directory of Open Access Journals (Sweden)

    Harryanto Wijaya

    2012-09-01

    Full Text Available Background: Anchorage is one of the major concerns in orthodontic space closure. Various methods have been proposed to enhance posterior anchorage in space closure such as headgear, Nance holding appliance, and micro implant as temporary anchorage devices. However, several issues such as patient's compliance, appliance effectiveness, and cost of the device become many clinicians concern. The differential moment concept in segmented arch is a technique that requires no patient compliance but can effectively manage posterior anchorage and avoid bite deepening by careful application of forces and moments. Purpose: The purpose of this case report is to show the use of differential moment concept in segmented arch technique to manage posterior anchorage and to avoid bite deepening. Case: A 21 years old female patient with protrusive teeth as her chief complaint was treated using fixed orthodontic appliance. Case management: The treatment included four first bicuspid extraction and space closure utilizing differential moment concept in segmented arch. Conclusion: It can be concluded that application of differential moment concept in segmented arch technique is a non invasive, compliance independent, effective, and cost efficient method to manage posterior anchorage and to avoid bite deepening.latar belakang: Penjangkaran merupakan salah satu aspek yang sering kali menjadi masalah dalam penutupan ruang pada perawatan ortodonti. Berbagai metode disarankan untuk memperkuat penjangkaran posterior dalam penutupan ruang seperti headgear, piranti penahan Nance, dan implan mikro sebagai alat penjangkar sementara. Namun demikian, beberapa hal seperti kerjasama pasien, efektivitas piranti, dan biaya dari alat-alat tersebut sering menjadi perhatian/pertimbangan bagi klinisi. Konsep momen diferensial pada segmented arch adalah suatu cara yang efektif untuk memperkuat penjangkaran dan menghindari pendalaman gigitan tanpa memerlukan kerjasama pasien. tujuan

  20. Anchorage of machined and TPS-coated dental implants of various lengths: An in vivo study in the dog maxilla

    OpenAIRE

    Carrel, Jean-Pierre; Szmukler-Moncler, Serge; Bernard, Jean-Pierre; Belser, Urs Christophe; Vazquez, Lydia

    2013-01-01

    The use of short implants is nowadays frequent in daily practice. The objective of this experimental study was to test the correlation between extremely different implant surfaces and the anchorage of short implants

  1. Application of a New Anchorage towards the Flexural Strengthening of RC Rectangular Beams with External Steel Tendons

    Directory of Open Access Journals (Sweden)

    Sungnam Hong

    2016-04-01

    Full Text Available To strengthen concrete beams, a new anchorage was proposed, and its performance was evaluated in this study. Seven concrete beams were manufactured and flexurally loaded with displacement control up to the failure point. As important test variables, the anchorage type (new/conventional and the prestress levels in the steel rebar (0, 50, and 100 kN were selected. To investigate the strengthening effects based on these test variables, the deflection, strain, and failure mode were recorded, and then the load, ductility index, and energy ratio were analyzed. Test results showed that the newly proposed end anchorage had better strengthening effects and a greater inelastic energy than the conventional end anchorages.

  2. Anchorage onto deciduous teeth: effectiveness of early rapid maxillary expansion in increasing dental arch dimension and improving anterior crowding

    OpenAIRE

    Mutinelli, Sabrina; Manfredi, Mario; Guiducci, Antonio; Denotti, Gloria; Cozzani, Mauro

    2015-01-01

    Background Anchorage onto permanent dentition is a common procedure in rapid maxillary expansion. However, replacing first permanent molars with the second deciduous molars seems to be an option to reduce some negative side effects during orthodontic treatment. The purpose of this study was to evaluate the dental effect of rapid maxillary expansion with anchorage exclusively onto deciduous teeth performed in the first period of transition. Methods Twenty patients with a lateral cross-bite tre...

  3. A genetic algorithm for dynamic parameters reverse deduction of integrated anchorage system

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In the analysis of the system of anchoring bar and wall rock in small strain and longitudinal vibration dynamic response, the influence of the cement grouting as well as the rock layer on the anchor bar can be evaluated as the two kinds of parameters: the dynamic stiffness and the damp, which are the vital reference of the anchorage quality. Based on the analytic solution to the dynamic equation of the integrated anchor bar, the new approach which combines genetic algorithm and the toolbox of Matlab is applied to solve the problem of multi-parameters reverse deduction for integrated anchorage system in dynamic testing. Using the traits of the self-organizing, self-adapting and the fast convergence speed of the genetic algorithm, the optimum of all possible solutions to dynamic parameters is obtained by calculating the project instances. Examples show that the method presented in this paper is effective and reliable.

  4. Impedance-Based Cable Force Monitoring in Tendon-Anchorage Using Portable PZT-Interface Technique

    Directory of Open Access Journals (Sweden)

    Thanh-Canh Huynh

    2014-01-01

    Full Text Available In this paper, a portable PZT interface for tension force monitoring in the cable-anchorage subsystem is developed. Firstly, the theoretical background of the impedance-based method is presented. A few damage evaluation approaches are outlined to quantify the variation of impedance signatures. Secondly, a portable PZT interface is designed to monitor impedance signatures from the cable-anchorage subsystem. One degree-of-freedom analytical model of the PZT interface is established to explain how to represent the loss of cable force from the change in the electromechanical impedance of the PZT interface as well as reducing the sensitive frequency band by implementing the interface device. Finally, the applicability of the proposed PZT-interface technique is experimentally evaluated for cable force-loss monitoring in a lab-scaled test structure.

  5. Inclusion of CFRP-Epoxy Composite for End Anchorage in NSM-Epoxy Strengthened Beams

    Directory of Open Access Journals (Sweden)

    Md. Akter Hosen

    2015-01-01

    Full Text Available Nowadays, the use of near surface mounted (NSM technique strengthening reinforced concrete (RC structural members is going very popular. The failure modes of NSM strengthened reinforced concrete (RC beams have been shown to be largely due to premature failure such as concrete cover separation. In this study, CFRP U-wrap end anchorage with CFRP fabrics was used to eliminate the concrete cover separation failure. A total of eight RC rectangular beam specimens of 125 mm width, 250 mm depth, and 2300 mm length were tested. One specimen was kept unstrengthened as a reference; three specimens were strengthened with NSM steel bars and the remaining four specimens were strengthened with NSM steel bars together with the U-wrap end anchorage. The experimental results showed that wrapped strengthened beams had higher flexural strength and superior ductility performance. The results also show that these beams had less deflection, strain, crack width, and spacing.

  6. Aiolos Promotes Anchorage Independence by Silencing p66Shc Transcription in Cancer Cells

    OpenAIRE

    Li, Xichuan; Xu, Zhao; Du, Wei; Zhang, Zhenfa; Wei, Yiliang; Wang, Hao; Zhu, Zhiyan; Qin, Litao; Wang, Lin; Niu, Qing; Zhao, Xiulan; Girard, Luc; Gong, Yimei; Ma, Zhenyi; Sun, Baocun

    2014-01-01

    Anchorage of tissue cells to their physical environment is an obligate requirement for survival which is lost in mature hematopoietic and in transformed epithelial cells. Here we find that a lymphocyte lineage-restricted transcription factor, Aiolos, is frequently expressed in lung cancers and predicts markedly reduced patient survival. Aiolos decreases expression of a large set of adhesion-related genes, disrupting cell-cell and cell-matrix interactions. Aiolos also reconfigures chromatin st...

  7. Impedance monitoring at tendon-anchorage via mountable PZT interface and temperature-effect compensation

    Science.gov (United States)

    Huynh, Thanh-Canh; Nguyen, Tuan-Cuong; Choi, Sang-Hoon; Kim, Jeong-Tae

    2016-04-01

    In this study, the pre-stress force in pre-stressed concrete (PSC) girders is monitored via mountable PZT interface under varying temperature. Firstly, an impedance-based technique using mountable PZT interface is proposed for pre-stress-loss monitoring in tendon-anchorage systems. A cross correlation-based temperature-effect compensation algorithm using an effective frequency shift (EFS) of impedance signatures is visited. Secondly, lab-scale experiments are performed on a PSC girder instrumented with a mountable PZT interface at tendon-anchorage. A series of temperature variation and pre-stress-loss events are simulated for the lab-scale PSC girder. Thirdly, the feasibility of the mountable PZT interface for pre-stress-loss monitoring in tendon-anchorage is experimentally verified under constant temperature conditions. Finally, the PZT interface device is examined for pre-stress-loss monitoring under temperature changes to validate its applicability. The temperature effect on impedance signatures is compensated by minimizing cross-correlation deviation between impedance patterns of the mountable PZT interface.

  8. HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth

    Directory of Open Access Journals (Sweden)

    Motoko Shibanuma

    2012-01-01

    Full Text Available HIC-5 is a multidomain LIM protein homologous to paxillin that serves as a molecular scaffold at focal adhesions and in the nucleus. It forms mobile molecular units with LIM-only proteins, PINCH, and CRP2 and translocates in and out of the nucleus via a nuclear export signal (NES. Of note, NES of HIC-5 is distinctive in its sensitivity to the cellular redox state. Recently, the mobile units of HIC-5 have been suggested to be involved in the regulation of the anchorage dependence of cell growth. On loss of adhesion, an increase in reactive oxygen species in the cells modifies NES and stops shuttling, which leads to cell-cycle control. More specifically, the system circumvents nuclear localization of cyclin D1 and transactivates p21Cip1 in detached cells, thereby avoiding anchorage-independent cell growth. Thus, the HIC-5-LIM only protein complex has emerged as a fail-safe system for regulating the anchorage dependence of cell growth.

  9. Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells.

    Directory of Open Access Journals (Sweden)

    Chia Chu

    Full Text Available The epithelial-mesenchymal transition (EMT is a complex cancer progression that can boost the metastatic potential of transformed cells by inducing migration, loss of cell adhesion, and promoting proliferation under anchorage-independent conditions. A DNA microarray analysis was performed comparing parental anchorage-dependent MDCK cells and anchorage-independent MDCK cells that were engineered to express human siat7e (ST6GALNAC5. The comparison identified several genes involved in the EMT process that were differentially expressed between the anchorage-dependent and the anchorage-independent MDCK cell lines. The hepatocyte growth factor gene (hgf was found to be over-expressed in the engineered MDCK-siat7e cells at both transcription and protein expression levels. Phosphorylation analysis of the MET receptor tyrosine kinase confirmed the activation of an autocrine loop of the HGF/ MET signaling pathway in the MDCK-siat7e cells. When MET activities were suppressed by using the small-molecular inhibitor drug PF-02341066 (Crizotinib, the anchorage-independent MDCK-siat7e cells reverted to the cellular morphology of the parental anchorage-dependent MDCK cells. These observations indicate that the MET receptor plays a central role in the growth properties of the MDCK cells and its phosphorylation status is likely dependent on sialylation. Further investigation of the downstream signaling targets in the MET network showed that the degree of MDCK cell adhesion correlated with secretion levels of a matrix metalloproteinase, MMP1, suggesting a role of metalloproteinases in the EMT process. These results demonstrate that in addition to its application in biotechnology processes, MDCK-siat7e may serve as a model cell for metastasis studies to decipher the sequence of events leading up to the activation of EMT.

  10. Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells.

    Science.gov (United States)

    Chu, Chia; Bottaro, Donald P; Betenbaugh, Michael J; Shiloach, Joseph

    2016-01-01

    The epithelial-mesenchymal transition (EMT) is a complex cancer progression that can boost the metastatic potential of transformed cells by inducing migration, loss of cell adhesion, and promoting proliferation under anchorage-independent conditions. A DNA microarray analysis was performed comparing parental anchorage-dependent MDCK cells and anchorage-independent MDCK cells that were engineered to express human siat7e (ST6GALNAC5). The comparison identified several genes involved in the EMT process that were differentially expressed between the anchorage-dependent and the anchorage-independent MDCK cell lines. The hepatocyte growth factor gene (hgf) was found to be over-expressed in the engineered MDCK-siat7e cells at both transcription and protein expression levels. Phosphorylation analysis of the MET receptor tyrosine kinase confirmed the activation of an autocrine loop of the HGF/ MET signaling pathway in the MDCK-siat7e cells. When MET activities were suppressed by using the small-molecular inhibitor drug PF-02341066 (Crizotinib), the anchorage-independent MDCK-siat7e cells reverted to the cellular morphology of the parental anchorage-dependent MDCK cells. These observations indicate that the MET receptor plays a central role in the growth properties of the MDCK cells and its phosphorylation status is likely dependent on sialylation. Further investigation of the downstream signaling targets in the MET network showed that the degree of MDCK cell adhesion correlated with secretion levels of a matrix metalloproteinase, MMP1, suggesting a role of metalloproteinases in the EMT process. These results demonstrate that in addition to its application in biotechnology processes, MDCK-siat7e may serve as a model cell for metastasis studies to decipher the sequence of events leading up to the activation of EMT. PMID:26848584

  11. Comparative evaluation of sagittal anchorage loss in lingual and labial appliances during space closure: A pilot study

    Directory of Open Access Journals (Sweden)

    Shivanand Venkatesh

    2015-01-01

    Full Text Available Aim: The purpose of this investigation was to assess and compare the anchorage loss between labial and lingual appliance systems during space closure. Materials and Methods: Twenty subjects were part of the study among which 10 subjects (mean age 21 ± 3.6 years were treated using lingual appliance system (0.018" slot-STb™ and 10 subjects (mean age 19 ± 6.1 years were treated using labial preadjusted edgewise appliance system (0.018" slot-MBT™ . First premolar extractions were performed to enable retraction of anterior teeth. Lateral cephalometric radiographs were taken at two intervals, before starting space closure and after space closure that were connoted as T0 and T1 and were analyzed using the method described by Pancherz to measure anchorage loss. Intraclass correlation coefficient (ICC was used to evaluate intraexaminer reliability of the measurements. Student′s t-test was performed to verify any statistical significant correlation between the labial and lingual appliance systems. Statistical differences were determined at the 95% confidence level (P < 0.05. Results: The results showed that all ICC for lingual and labial group were ≥0.90 showing good repeatability of the measurements. Mean anchorage loss of 1.238 ± 0.17 mm in lingual appliance system and an anchorage loss of 2.06 ± 0.39 mm occurred with the labial appliance system. On the comparison between the two appliance systems, lingual appliance demonstrated a significantly lesser anchorage loss than did the labial appliance. Interpretation and Conclusion: This prospective study concludes with the fact that lingual appliance provided better anchorage control than labial appliance during space closure. Use of lingual appliance could be considered in critical anchorage cases when compared with labial appliance.

  12. EFFECT OF END ANCHORAGE LENGTH AND STIRRUP RATIO ON BOND AND SHEAR CAPACITY OF CONCRETE BEAMS WITH NONMETALLIC REINFORCEMENT

    Directory of Open Access Journals (Sweden)

    RENDY THAMRIN

    2016-06-01

    Full Text Available This paper presents a study on the effect of end anchorage length and stirrup ratio on bond and shear capacity of concrete beams reinforced with Carbon Fiber Reinforced Polymer (CFRP bars. This study was carried out using test data on nine simply supported reinforced concrete beams with stirrups. The beams were subjected to two point monotonic loads and the test variables were the length of end anchorage and the stirrup ratio. Theoretical equations for calculating bond strength and shear capacity obtained from literature were applied and then compared with experimental values. Beams with inadequate end anchorage length showed premature bond failure even when there was sufficient stirrup ratio. Beams with adequate end anchorage length failed in shear or flexure modes depending on the stirrup ratio. A numerical model for bond stress and slip in response to pullout forces was also used to determine analytically the bond stress distributions along end anchorage. The behavior of tensile force acting on the stirrups was also examined. Finally, a simple model for predicting tension force acting on the stirrups was proposed.

  13. Verification of the local structural response of building structures in the anchorage areas of heavy components

    International Nuclear Information System (INIS)

    In conventional dynamic structural analyses for determining dynamic system response for various locations at which components are installed inside the structures it is common practice (in order to simplify analytical effort) to assume that the anchorage (anchor plate, anchor bolts or throughbolts, concrete and reinforcement in the area of bound) has rigid body characteristics and that the building structure itself does not display any local response of its own. The influence of the stiffness of the anchor plate as well anchor bolts and its stress level on the dynamic response is also neglected. For a large number of anchoring systems, especially for all those components and systems having only a small mass, this assumption is certainly appropriate. At some locations, particularly at points where heavy components are anchored or when loading input has been increased, this can lead to local loading of the anchor system as well as of the building structure well into the nonlinear range. Often, verification of capability to accommodate these loads is not possible without changing the wall thicknesses or increasing the percentage of reinforcement. Since the presence of linear or nonlinear effects can be expected to result in energy dissipation (increase in damping capacity and also a change in the stiffness of the coupled system) it must be assumed that the dynamic response between the theoretical coupling point A and the real connection point B of the component on the anchor plate can be considerably altered. Some changes of the dynamic response in the connection point B have to be expected generally even in cases of linear-elastic loading of the anchorage. Using typical anchoring systems as an example, the influence of consideration of nonlinear effects in the anchorage area of a typical anchor plate on the dynamic response as well as the conservatism of conventional analytical approaches are investigated

  14. Detection of bond failure in the anchorage zone of reinforced concrete beams via acoustic emission monitoring

    Science.gov (United States)

    Abouhussien, Ahmed A.; Hassan, Assem A. A.

    2016-07-01

    In this study, acoustic emission (AE) monitoring was utilised to identify the onset of bond failure in reinforced concrete beams. Beam anchorage specimens were designed and tested to fail in bond in the anchorage zone. The specimens included four 250 × 250 × 1500 mm beams with four variable bonded lengths (100, 200, 300, and 400 mm). Meanwhile, an additional 250 × 250 × 2440 mm beam, with 200 mm bonded length, was tested to investigate the influence of sensor location on the identification of bond damage. All beams were tested under four-point loading setup and continuously monitored using three distributed AE sensors. These attached sensors were exploited to record AE signals resulting from both cracking and bond deterioration until failure. The variations in the number of AE hits and cumulative signal strength (CSS) versus test time were evaluated to achieve early detection of crack growth and bar slippage. In addition, AE intensity analysis was performed on signal strength of collected AE signals to develop two additional parameters: historic index (H (t)) and severity (S r). The analysis of these AE parameters enabled an early detection of both first cracks (at almost the mid-span of the beam) and bar slip in either of the anchorage zones at the beams’ end before their visual observation, regardless of sensor location. The results also demonstrated a clear correlation between the damage level in terms of crack development/measured free end bar slip and AE parameters (number of hits, CSS, H(t), and S r).

  15. Impact of a new gasoline benzene regulation on ambient air pollutants in Anchorage, Alaska

    Science.gov (United States)

    Yano, Yuriko; Morris, Stephen S.; Salerno, Christopher; Schlapia, Anne M.; Stichick, Mathew

    2016-05-01

    The purpose of this study was to quantify the impact of a new U.S. Environmental Protection Agency (EPA) standard that limits the amount of benzene allowed in gasoline on ambient benzene concentrations. This new standard, together with two companion regulations that limit cold-temperature automotive emissions and the permeability of portable fuel containers, was expected to lower the levels of ambient benzene and other volatile organic compounds (VOCs) nationwide. In this study the impact of the gasoline benzene standard was evaluated in Anchorage, Alaska in a two-phase ambient air monitoring study conducted before and after the new gasoline standard was implemented. Gasoline sold by Anchorage retailers was also evaluated in each phase to determine the content of benzene and other gasoline components. The average benzene content in Anchorage gasoline was reduced by 70%, from 5.05% (w/w) to 1.53% (w/w) following the implementation of the standard. The annual mean ambient benzene concentration fell by 51%, from 0.99 ppbv in Phase 1 to 0.49 ppbv in Phase 2. Analysis suggests the change in gasoline benzene content alone reduced benzene emissions by 46%. The changes in toluene, ethylbenzene, and xylene content in gasoline between Phase 1 and 2 were relatively small and the differences in the mean ambient concentrations of these compounds between phases were modest. Our results suggest that cold winter communities in high latitude and mountainous regions may benefit more from the gasoline benzene standard because of high benzene emissions resulting from vehicle cold start and a tendency to develop atmospheric stagnation conditions in the winter.

  16. Corticotomy-assisted molar protraction with the aid of temporary anchorage device.

    Science.gov (United States)

    Uribe, Flavio; Janakiraman, Nandakumar; Fattal, Amine N; Schincaglia, Gian Pietro; Nanda, Ravindra

    2013-11-01

    This case report describes the interdisciplinary management of a 58-year-old woman who was missing lower first molars and supraerupted maxillary first molars. The treatment plan included intrusion of the upper first molars and corticotomy-assisted mandibular second molar protraction with the aid of temporary anchorage devices. Miniscrews were effective in intrusion of the maxillary first molars and protraction of the lower second molars. Although good functional outcome was achieved in 41 months, the corticotomy-assisted procedure did not significantly reduce the treatment time. PMID:23834274

  17. Concentrations of fecal coliform bacteria in creeks, Anchorage, Alaska, August and September 1998

    Science.gov (United States)

    Dorava, Joseph M.; Love, Andra

    1999-01-01

    Water samples were collected from five creeks in undeveloped, semi-developed, and developed areas of Anchorage, Alaska, during August and September 1998 to determine concentrations of fecal coliform bacteria. In undeveloped areas of Ship, Chester, and Campbell Creeks, and the semi-developed area of Rabbit Creek, concentrations of fecal coliform bacteria ranged from less than 1 to 16 colonies per 100 milliliters of water. In the semi-developed area of Little Rabbit Creek, concentrations ranged from 30 to 860 colonies per 100 milliliters of water. In developed areas of the creeks, concentrations of fecal coliform bacteria ranged from 6 to 80 colonies per 100 milliliters of water.

  18. Dental Extrusion with Orthodontic Miniscrew Anchorage: A Case Report Describing a Modified Method

    Directory of Open Access Journals (Sweden)

    Ricardo Fidos Horliana

    2015-01-01

    Full Text Available In recent years, the skeletal anchorage through miniscrews has expanded the treatment options in orthodontics (Yamaguchi et al., 2012. We hereby present a modified method for tooth extrusion for cases where crown-lengthening surgery is contraindicated for aesthetic reasons. This modified method uses three orthodontic appliances: a mini-implant, an orthodontic wire, and a bracket. The aim of this case report was to increase the length of the clinical crown of a fractured tooth (tooth 23 by means of an orthodontic extrusion with the modified method of Roth and Diedrich.

  19. Wind loads analysis at the anchorages of the Talavera de la Reina cable stayed bridge

    Directory of Open Access Journals (Sweden)

    L. Rosa

    2014-06-01

    Full Text Available This paper describes wind tunnel tests performed on wind tunnel models of the Talavera de la Reina cable stayed bridge. The work describes the aeroelastic model construction and it is focused on the evaluation and analysis of the mean and peak wind loads at the tower foundation and the cable anchorages since these data can be very useful by the bridge manufacturer as a support for the bridge design. The work is part of a complete wind tunnel study carried out to analyze the aeroelastic stability of the bridge.

  20. Self-assembled peptide-based hydrogels as scaffolds for anchorage-dependent cells.

    Science.gov (United States)

    Zhou, Mi; Smith, Andrew M; Das, Apurba K; Hodson, Nigel W; Collins, Richard F; Ulijn, Rein V; Gough, Julie E

    2009-05-01

    We report here the design of a biomimetic nanofibrous hydrogel as a 3D-scaffold for anchorage-dependent cells. The peptide-based bioactive hydrogel is formed through molecular self-assembly and the building blocks are a mixture of two aromatic short peptide derivatives: Fmoc-FF (Fluorenylmethoxycarbonyl-diphenylalanine) and Fmoc-RGD (arginine-glycine-aspartate) as the simplest self-assembling moieties reported so far for the construction of small-molecule-based bioactive hydrogels. This hydrogel provides a highly hydrated, stiff and nanofibrous hydrogel network that uniquely presents bioactive ligands at the fibre surface; therefore it mimics certain essential features of the extracellular matrix. The RGD sequence as part of the Fmoc-RGD building block plays a dual role of a structural component and a biological ligand. Spectroscopic and imaging analysis using CD, FTIR, fluorescence, TEM and AFM confirmed that FF and RGD peptide sequences self-assemble into beta-sheets interlocked by pi-pi stacking of the Fmoc groups. This generates the cylindrical nanofibres interwoven within the hydrogel with the presence of RGDs in tunable densities on the fibre surfaces. This rapid gelling material was observed to promote adhesion of encapsulated dermal fibroblasts through specific RGD-integrin binding, with subsequent cell spreading and proliferation; therefore it may offer an economical model scaffold to 3D-culture other anchorage-dependent cells for in-vitro tissue regeneration. PMID:19201459

  1. Behaviour of Plate Anchorage in Plate-Reinforced Composite Coupling Beams

    Directory of Open Access Journals (Sweden)

    W. Y. Lam

    2013-01-01

    Full Text Available As a new alternative design, plate-reinforced composite (PRC coupling beam achieves enhanced strength and ductility by embedding a vertical steel plate into a conventionally reinforced concrete (RC coupling beam. Based on a nonlinear finite element model developed in the authors’ previous study, a parametric study presented in this paper has been carried out to investigate the influence of several key parameters on the overall performance of PRC coupling beams. The effects of steel plate geometry, span-to-depth ratio of beams, and steel reinforcement ratios at beam spans and in wall regions are quantified. It is found that the anchorage length of the steel plate is primarily controlled by the span-to-depth ratio of the beam. Based on the numerical results, a design curve is proposed for determining the anchorage length of the steel plate. The load-carrying capacity of short PRC coupling beams with high steel ratio is found to be controlled by the steel ratio of wall piers. The maximum shear stress of PRC coupling beams should be limited to 15 MPa.

  2. Behaviour of plate anchorage in plate-reinforced composite coupling beams.

    Science.gov (United States)

    Lam, W Y; Li, Lingzhi; Su, R K L; Pam, H J

    2013-01-01

    As a new alternative design, plate-reinforced composite (PRC) coupling beam achieves enhanced strength and ductility by embedding a vertical steel plate into a conventionally reinforced concrete (RC) coupling beam. Based on a nonlinear finite element model developed in the authors' previous study, a parametric study presented in this paper has been carried out to investigate the influence of several key parameters on the overall performance of PRC coupling beams. The effects of steel plate geometry, span-to-depth ratio of beams, and steel reinforcement ratios at beam spans and in wall regions are quantified. It is found that the anchorage length of the steel plate is primarily controlled by the span-to-depth ratio of the beam. Based on the numerical results, a design curve is proposed for determining the anchorage length of the steel plate. The load-carrying capacity of short PRC coupling beams with high steel ratio is found to be controlled by the steel ratio of wall piers. The maximum shear stress of PRC coupling beams should be limited to 15 MPa. PMID:24288465

  3. 33 CFR 165.110 - Safety and Security Zone; Liquefied Natural Gas Carrier Transits and Anchorage Operations, Boston...

    Science.gov (United States)

    2010-07-01

    ... United States within the Captain of the Port (COTP) Boston zone, as defined in 33 CFR 3.05-10, two miles... listed in 33 CFR 150.490 and falling within the waters of the Boston COTP Zone, as defined in 33 CFR 3.05...; Liquefied Natural Gas Carrier Transits and Anchorage Operations, Boston, Massachusetts. 165.110 Section...

  4. The "Real Self" and Inauthenticity: The Importance of Self-Concept Anchorage for Emotional Experiences in the Workplace

    Science.gov (United States)

    Sloan, Melissa M.

    2007-01-01

    I examine the utility of self-concept anchorage (as described by Turner 1976) in the analysis of inauthenticity in the workplace. As controlling internally felt emotion may distance the worker from her true feelings or true self, the management of emotion in the workplace can produce feelings of inauthenticity in the worker. This relationship has…

  5. Orthodontic retreatment using anchorage with miniplate to camouflage a Class III skeletal pattern.

    Science.gov (United States)

    Farret, Marcel Marchiori

    2016-06-01

    This manuscript describes the treatment of a 27-year-old patient who was previously treated with two maxillary first premolar extractions. The patient had skeletal Class III malocclusion, Class III canine relationship, anterior crossbite, and a concave profile. As the patient refused orthognathic surgery, a miniplate was used on the right side of the lower arch as an anchorage unit after the extraction of mandibular first premolars, aiding the retraction of anterior teeth. At the end of treatment, anterior crossbite was corrected, in which first molars and canines were in a Class I relationship, and an excellent intercuspation was reached. Furthermore, patient's profile remarkably improved as a result of mandibular incisor retraction. A 30-month follow-up showed good stability of the results obtained. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as one of the requirements to become diplomate by the BBO. PMID:27409659

  6. Denmark: criminal law as an anchorage point for pro-active anti-terrorism legislation

    DEFF Research Database (Denmark)

    Vestergaard, Jørn

    2012-01-01

    The article focuses on the compatibility of criminal law anti-terrorism legislation in Danish law with basic principles regarding the rule of law and due process. The so-called anti-terror-packages of 2002 and 2006 involve a set of rather uncertain and wide-reaching provisions fundamentally...... instruments binding on Denmark by virtue of EU law or international obligations. And the statutes have been drafted in a somewhat loose manner without sufficiently thorough legislative preparations. The provisions in the Penal Code constitute an anchorage point for all other anti-terrorism legislation. Thus......, the challenges regarding rule of law and due process also relate to secondary legislation in fields like law enforcement, criminal procedure, intelligence, public law, treatment of foreigners, etc....

  7. Anchorage Test of A New-style Water-fast Anchorage Agent and Engineering Application%新型耐水锚固剂锚固试验研究及工程应用

    Institute of Scientific and Technical Information of China (English)

    王正胜

    2015-01-01

    Selectinghigh-strength modified polyester which could trigger solidification in water environment, water-fast anchorage agent was developed successfully.Research showed that action system of PM-Ⅰ and solidification agent-Ⅰ made solidification effect be the best and anchorage strength the biggest under normal temperature environment, and that pulling resistance could reach above 240kN after 24 hours under anhydrous condition, it could reach above 200kN under water condition.In simulated borehole with seamless steel tube with 28mm inner diameter and 800mm length, anchorage strength of 2 self-made 2330 anchorage agents reached 273kN.This new-style water-fast anchorage agent was successfully applied in floor-heave main air-return roadway of 2nd mining region in Jiangjiahe Col-liery, which improved construction efficiency, shortened construction time and reduced the influence of water on anchorage force of floor anchored cable.%选取本身强度高,水域环境内能稳定引发固化的改性聚酯为主体,研制成功耐水锚固剂。研究表明: PM-Ⅰ和固化剂-Ⅰ反应体系,常温固化效果最好、锚固强度最高;无水条件下24h后抗拔力达到240kN以上,有水条件下24h后抗拔力达到200kN以上;内径28mm、长800mm无缝钢管模拟钻孔中,自制2330锚固剂2支,锚固锚索24h后锚固强度可达273kN。新型耐水锚固剂于蒋家河煤矿二号采区回风大巷底鼓段试验成功,且提高施工效率、缩短工期,减少了水对底板锚索锚固力降低的影响。

  8. Bio-cultural anchorage of the prickly pear cactus in Tlalnepantla (Morelos, Mexico

    Directory of Open Access Journals (Sweden)

    Torres-Salcido, Gerardo

    2016-06-01

    Full Text Available The prickly pear cactus is a source of food with strong bio-cultural anchorage in Mexico. This is due to at least three factors: 1 the nature and heritage of cacti; 2 cultural heritage; and 3 the socio-cultural relationships with historical and symbolic roots that have facilitated knowledge of how to cultivate it and how to use it. The aim of this article is to put factors of territorial anchorage and its historical transformation in context by examining the case of the municipality of Tlalnepantla in the state of Morelos, Mexico. This community has experienced accelerated change due to the exchange of traditional crops for the prickly pear cactus and the integration of farming, commercialization and agro-transformation. Our hypothesis is that the market, internal conflicts and a lack of socio-institutional coordination have put social organization into crisis, favoring the territorial spread of the prickly pear cactus and making the Local Agro-Food Systems (LAFS of Tlalnepantla less competitive. The conclusions highlight important economic and social advances whose roots lie in the strengthening and anchorage of the territory-product. However, circumstances both internal and external to the community persist, such as intra-community conflicts, the international market and cultural paradigm shifts that affect the producers and put consolidation of the LAFS at risk.El nopal es un alimento con un fuerte anclaje bio-cultural en México, propiciado por al menos tres factores: 1 la naturaleza y el patrimonio de cactáceas; 2 el patrimonio cultural; y, 3 las relaciones socio-culturales que han permitido un “saber hacer” y un “saber utilizar” con raíces históricas y simbólicas. El objetivo es situar los factores de anclaje territorial y su transformación histórica tomando como caso el municipio de Tlalnepantla, en el estado de Morelos, México. Esta comunidad ha experimentado un acelerado cambio por la reconversión de los cultivos

  9. Consecutive condylectomy and molar intrusion using temporary anchorage devices as an alternative for correcting facial asymmetry with condylar hyperplasia.

    Science.gov (United States)

    Choi, Yoon Jeong; Lee, Sang-Hwy; Baek, Man-Suk; Kim, Jae-Young; Park, Young-Chel

    2015-04-01

    This case report demonstrates the successful treatment of facial asymmetry with condylar hyperplasia with limited surgical and orthodontic treatment. A high condylectomy was performed to shorten the elongated condyle and to remove its active growth site. The maxillary molars on the affected side were then orthodontically intruded using temporary anchorage devices to improve the occlusal cant and posterior open bite of the unaffected side. This combined surgical-orthodontic treatment provided a satisfactory outcome without additional orthognathic surgery. PMID:25836342

  10. Internal structure of mandible around mandibular molar using computed tomography. Anatomical consideration of molar anchorage in orthodontic treatment

    International Nuclear Information System (INIS)

    For establishment of fine occlusion, facial profile and oral function in orthodontic treatment, molar anchorage in teeth movement is important manner in extracted cases. The aims of this study were to investigate the relationship between facial morphology and internal structure of mandibular body in molar region by computer tomography, and to discuss about molar anchorage in orthodontic treatment. The data for this study were obtained from 35 modern male Japanese skulls (mean age; 27 year-old, ranged from 18 year-old to 47 year-old). Measurement variables were FMA, SN to mandibular plane angle, gonial angle, alveolar breadth, cortical bone thickness of buccal and lingual sides, and the distance between dental root and cortical bone. As a result, alveolar breadth and the distance between dental root and cortical bone were narrow in long facial type, on the contrary, these variables were wide in short facial type. The result suggested that these variables were considered important factors as molar anchorage in extracted cases. (author)

  11. Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer

    Science.gov (United States)

    Feng, Ming-Xuan; Wang, Ya-Hui; Yang, Xiao-Mei; He, Ping; Tian, Guang-Ang; Zhang, Xiao-Xin; Li, Qing; Cao, Xiao-Yan; Huo, Yan-Miao; Yang, Min-Wei; Fu, Xue-Liang; Li, Jiao; Liu, De-Jun; Dai, Miao; Wen, Shan-Yun; Gu, Jian-Ren; Hong, Jie; Hua, Rong; Zhang, Zhi-Gang; Sun, Yong-Wei

    2016-01-01

    Epidermal Growth Factor-like repeats and Discoidin I-Like Domains 3 (EDIL3), an extracellular matrix (ECM) protein associated with vascular morphogenesis and remodeling, is commonly upregulated in multiple types of human cancers and correlates with tumor progression. However, its expression pattern and underlying cellular functions in pancreatic ductal adenocarcinoma (PDAC) remain largely unexplored. In current study, we observed that expression of EDIL3 was significantly up-regulated in PDAC compared with normal controls in both cell lines and clinical specimens. In addition, elevated EDIL3 expression was positively correlated with patients’ TNM stage and T classification. Kaplan-Meier analysis indicated that high EDIL3 expression was significantly associated with shorter overall survival times in PDAC patients. Multivariate Cox regression analysis confirmed EDIL3 expression, age, lymph node metastasis and histological differentiation as independent prognostic factors in PDAC. Knockdown of EDIL3 showed no significant influence on cell viability, migration, invasion and starvation-induced apoptosis, but compromised anoikis resistance and anchorage independent tumor growth of PDAC cells. Meanwhile, treatment with recombinant EDIL3 protein markedly promoted anoikis resistance and anchorage independent tumor growth. Mechanistically, we demonstrated that altered protein expression of Bcl-2 family might contribute to the oncogenic activities of EDIL3. In conclusion, this study provides evidences that EDIL3 is a potential predictor and plays an important role in anchorage independent tumor growth of PDAC and EDIL3-related pathways might represent a novel therapeutic strategy for treatment of pancreatic cancer. PMID:26735172

  12. Liquid marbles for high-throughput biological screening of anchorage-dependent cells.

    Science.gov (United States)

    Oliveira, Nuno M; Correia, Clara R; Reis, Rui L; Mano, João F

    2015-01-28

    Stable liquid marbles (LM) are produced by coating liquid droplets with a hydrophobic powder. The used hydrophobic powder is produced by fluorosi-lanization of diatomaceous earth, used before to produce superhydrophobic structures. Here, the use of LM is proposed for high-throughput drug screening on anchorage-dependent cells. To provide the required cell adhesion sites inside the liquid environment of LM, surface-modified poly(l-lactic acid) microparticles are used. A simple method that takes advantage from LM appealing features is presented, such as the ability to inject liquid on LM without disrupting (self-healing ability), and to monitor color changes inside of LM. After promoting cell adhesion, a cytotoxic screening test is performed as a proof of concept. Fe(3+) is used as a model cytotoxic agent and is injected on LM. After incubation, AlamarBlue reagent is injected and used to assess the presence of viable cells, by monitoring color change from blue to red. Color intensity is measured by image processing and the analysis of pictures takes using an ordinary digital camera. The proposed method is fully validated in counterpoint to an MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carbo​xymethoxyphenyl)-2-(4-sulfophenyl)-2H-te​trazolium) colorimetric assay, a well-known method used for the cytotoxicity assessment.

  13. Oral and dental restoration of wide alveolar cleft using distraction osteogenesis and temporary anchorage devices.

    Science.gov (United States)

    Rachmiel, Adi; Emodi, Omri; Gutmacher, Zvi; Blumenfeld, Israel; Aizenbud, Dror

    2013-12-01

    Closure of large alveolar clefts and restoration by a fixed bridge supported by implants is a challenge in cleft alveolus treatment. A major aesthetic concern with distraction osteogenesis is obtaining a predictable position of the implant in relation to the newly generated bony alveolar ridge. We describe the treatment of a large cleft alveolus and palate reconstruction by distraction osteogenesis utilizing temporary anchorage devices (TADs) followed by a fixed implant-supported bridge. The method consists of segmental bone transport by distraction osteogenesis using a bone-borne distractor to minimize the alveolar cleft, followed by closure of the residual small defect by bone grafting three months later. During the active transport distraction, TADs were used exerting multidirectional forces to control the distraction vector forward and laterally for better interarch relation. A vertical alveolar distraction of the newly reconstructed bone of 15 mm facilitated optimal implant placement. The endosseous implants were osteointegrated and supported a fixed dental prosthesis. In conclusion, the large cleft alveolus defect was repaired in three dimensions by distraction osteogenesis assisted by TADs, and the soft tissues expanded simultaneously. Endosseous implants were introduced in the newly reconstructed bone for a fixed dental prosthesis enabling, rehabilitation of aesthetics, eating and speaking.

  14. The perception of pain following interdental microimplant treatment for skeletal anchorage: a retrospective study.

    Science.gov (United States)

    Chen, Chun-Ming; Chang, Chao-San; Tseng, Yu-Chuan; Hsu, Kun-Rong; Lee, Kun-Tsung; Lee, Huey-Er

    2011-01-01

    During orthodontic therapy, patients frequently complain about pain and discomfort, especially during insertion of fixed appliances. Skeletal anchorage using an interdental microimplant is a new concept in orthodontic treatment. The purpose of this study was to investigate differences and changes in the level of pain among patients in relation to orthodontic microimplant treatments. Forty microimplants were applied to the maxilla as skeletal anchors in the orthodontic treatment. The visual analog scale (VAS) was used to evaluate the patients' perception of pain during this new modality treatment. The premolar extraction VAS core was used as a baseline for the complete orthodontic procedure. The mean VAS score was 35.8 mm at 24 h after premolar extraction. The mean VAS score for insertion and removal of the microimplant 24 h after the operation was 12.3 and 7.8 mm, respectively. Three months after removal of the skeletal anchors, the VAS score had decreased to 3.2 mm and was the same as with the traditional orthodontic treatment. By using the repeated-measure general linear model (GLM), we found that the score 1 day after microimplant placement was significantly less than that 1 day after first premolar extraction or that 1 day after fixed appliance insertion. This result indicates that interdental microimplant did not generate any greater pain than other orthodontic procedures. Therefore, patients were willing to adopt the new orthodontic treatment.

  15. Research on the video detection device in the invisible part of stay cable anchorage system

    Science.gov (United States)

    Cai, Lin; Deng, Nianchun; Xiao, Zexin

    2012-11-01

    The cables in anchorage zone of cable-stayed bridge are hidden within the embedded pipe, which leads to the difficulty for detecting the damage of the cables with visual inspection. We have built a detection device based on high-resolution video capture, realized the distance observing of invisible segment of stay cable and damage detection of outer surface of cable in the small volume. The system mainly consists of optical stents and precision mechanical support device, optical imaging system, lighting source, drived motor control and IP camera video capture system. The principal innovations of the device are ⑴A set of telescope objectives with three different focal lengths are designed and used in different distances of the monitors by means of converter. ⑵Lens system is far separated with lighting system, so that the imaging optical path could effectively avoid the harsh environment which would be in the invisible part of cables. The practice shows that the device not only can collect the clear surveillance video images of outer surface of cable effectively, but also has a broad application prospect in security warning of prestressed structures.

  16. 关于支抗和支抗力科学内涵的辨析%Scientific connotation analysis on anchorage and resistance

    Institute of Scientific and Technical Information of China (English)

    陈勃

    2011-01-01

    目的 明确口腔正畸学标志性术语一支抗和支抗力的科学内涵.方法 查阅历史相关文献并剖析其对支抗和支抗力定义的不科学性.结果 现有文献资料未能对支抗和支抗力作出科学的定义.结论 支抗和支抗力是口腔正畸学的标志性术语,明确其科学内涵有重要的理论价值和实践意义.它可以帮助提高临床正畸医师进行有效支抗控制的主动意识,并为各种外加的支抗加强装置提供科学的理论依据,可以说没有支抗和支抗力指导的有效支抗控制就不可能有理想的正畸治疗效果.%Objective To clear the symbolic term in Orthodontics - anchorage and scientific connotation of resistance.Methods Searched history documents and dissected its unscientific definition to anchorage and resistance.Results Current document literature failed to give the scientific definition towards anchorage and resistance.Conclusion Anchorage and resistance are symbolic terms in orthodontics.Clarifying its scientific connotation has important theoretical value and practical significance.It can help orthodontist enhance active consciousness on controlling anchorage effectively.Besides,it can provide scientific theoretical basis for different kinds of additional anchorage strengthening devices.It can be said without the guidance of effective resistance anchorage control.We can say there won't be ideal orthodontic treatment.

  17. Research Progress of the Anchorage Control in Orthodontic Treatment%正畸治疗中支抗控制的研究进展

    Institute of Scientific and Technical Information of China (English)

    刘春利; 肖丹娜

    2015-01-01

    正畸治疗中支抗控制至关重要,合理的支抗设计关系到治疗的成败。支抗控制可从支抗加强和支抗节省两方面考虑,并在治疗过程中联合应用。正畸治疗效果需以多维效果评价,为取得优质的治疗效果支抗需根据患者的垂直骨面型、牙颌畸形的类型,在矢状向、垂直向、水平向进行控制。该文就目前常用的加强支抗的方法进行简要概括,同时对新兴加强支抗的设计进行简要总结,并对支抗节省的理念、操作和矫治系统的选择进行综述。%The anchorage control is very important in orthodontic treatment,and good design matters to the success or failure of the treatment.Anchorage control includes two aspects of anchorage strengthening and anchorage saving,which both should be taken into consideration,and joint applied in the process of treat-ment.Effect of orthodontic treatment needs multidimensional performance evaluation,to achieve high quality of treatment,sagittal,vertical,and horizontal control should be done according to patients'vertical bone sur-face type and the type of teeth micromaxillary deformity.Here is to make a review of the common methods to strengthen the anchorage,as well as the emerging of strengthening anchorage design,and the idea of the anchorage saving,and the choices of operational and correctional systems.

  18. Mini-placa como ancoragem ortodôntica: relato de caso Mini screw as orthodontic anchorage: case report

    Directory of Open Access Journals (Sweden)

    André Luiz Zétola

    2005-08-01

    ígida pode ser utilizada com bastante propriedade no tratamento ortodôntico qunado for requerida uma ancoragem máxima.It is needless to say that anchorage control is necessary to a successful orthodontic treatment. Without it, it would be impossible to obtain an ideal occlusion through orthodontic mechanics in the majority of cases. The utilization of rigid devices, originated from face traumatology and implant dentistry principles, to obtain rigid anchorage in orthodontics revolutionized the way of treating cases with an unsatisfactory prognosis. Specially in cases where a lot of anchorage is needed and it is difficult or impossible to get it. The objective of this article was to revise the literature related to the use of mini-screw implant systems, to report a case where it was utilized and to discuss some aspects related to the usage of rigid anchorage orthodontics. The rigid anchorage was used in a 39 year old female patient, who had the upper left molars with a relevant extrusion due to the absence of the lower left molars. Fixed appliances were placed on the upper arch with a TPA connecting the second bicuspids. The TPA was used to anchor the intrusion of the upper left molars. A quad-helix appliance was used to correct the upper right third molar crossbite. Since the orthodontic intrusion with only dental anchorage did not have a satisfactory result, an "L" shaped titanium plate was placed on the maxilla, at the apical region of the upper first and second left molars, with the purpose of obtaining a rigid orthodontic anchorage to intrude them. Elastics were used during five months with intrusive force,the obtained intrusion was 6 millimeters. After the removal of the appliance, upper and lower dental bleaching was made and final prosthesis were placed over the implants. Through the literature reviewed and the case reported, it can be concluded that rigid anchorage can be indicated in orthodontic treatments where there is lack of anchorage or the need of an absolute

  19. Analysis on Optimum Anchorage Angle of Anchoring Bars (Ropes)%锚杆(索)最佳锚固角的取值分析

    Institute of Scientific and Technical Information of China (English)

    蒋明杰

    2013-01-01

      In the protection design of highway slope engineering , the anchorage design of anchoring bars (ropes) are more commonly protection method, while the anchorage angle in the design of anchoring bars (ropes) is a key parameter, which related to the stability and economy in whole anchoring slope engi-neering.Through the influences of anchorage angle on anchored slope engineering safety and economy , the comprehensive analysis is carried out,and the expression formula of optimum anchorage angle is deter-mined, finally through the engineering examples ,it verifies the practicality of optimum anchorage angle .%  在公路边坡工程的防护设计中,锚杆(索)的锚固设计是较常用的防护形式,而在锚杆(索)的设计中锚固角是很关键的一个参数,关系到整个锚固边坡工程的稳定性和经济性。该文通过综合分析锚杆(索)的锚固角对锚固边坡工程的安全性和经济性两方面的影响,确定了锚杆(索)最佳锚固角的表达式,并通过工程实例验证了最佳锚固角的实用性。

  20. Nitrate source indicators in ground water of the Scimitar Subdivision, Peters Creek area, Anchorage, Alaska

    Science.gov (United States)

    Wang, Bronwen; Strelakos, Pat M.; Jokela, Brett

    2000-01-01

    A combination of aqueous chemistry, isotopic measurement, and in situ tracers were used to study the possible nitrate sources, the factors contributing to the spatial distribution of nitrate, and possible septic system influence in the ground water in the Scimitar Subdivision, Municipality of Anchorage, Alaska. Two water types were distinguished on the basis of the major ion chemistry: (1) a calcium sodium carbonate water, which was associated with isotopically heavier boron and with chlorofluorocarbons (CFC's) that were in the range expected from equilibration with the atmosphere (group A water) and (2) a calcium magnesium carbonate water, which was associated with elevated nitrate, chloride, and magnesium concentrations, generally isotopically lighter boron, and CFC's concentrations that were generally in excess of that expected from equilibration with the atmosphere (group B water). Water from wells in group B had nitrate concentrations that were greater than 3 milligrams per liter, whereas those in group A had nitrate concentrations of 0.2 milligram per liter or less. Nitrate does not appear to be undergoing extensive transformation in the ground-water system and behaves as a conservative ion. The major ion chemistry trends and the presence of CFC's in excess of an atmospheric source for group B wells are consistent with waste-water influences. The spatial distribution of the nitrate among wells is likely due to the magnitude of this influence on any given well. Using an expanded data set composed of 16 wells sampled only for nitrate concentration, a significant difference in the static water level relative to bedrock was found. Well water samples with less than 1 milligram per liter nitrate had static water levels within the bedrock, whereas those samples with greater than 1 milligram per liter nitrate had static water levels near or above the top of the bedrock. This observation would be consistent with a conceptual model of a low-nitrate fractured bedrock

  1. Evaluation of the variable anchorage straightwire technique using Ricketts' growth prediction.

    Science.gov (United States)

    Parikakis, Konstantinos A; Moberg, Svante; Hellsing, Eva

    2009-02-01

    The purpose of this retrospective study was to evaluate the treatment effects of the variable anchorage straightwire technique (VAST) in Angle Class II patients using Ricketts' growth prediction analysis. The subjects belonged to two groups: a control, consisting of 30 untreated Class II Swedish individuals (20 girls, 10 boys) with a mean age of 11.2 years, and the other 29 Swedish patients (14 girls, 15 boys), mean age 12.6 years, post-normal and with an increased overbite (OB), treated with the VAST. Two lateral cephalograms were available for every individual. Growth prediction according to Ricketts' visual treatment objective (VTO) was used to estimate the expected growth increments for a 2-year period. It was first used in the control group to determine its validity and then applied to the treated group to evaluate the net effects of treatment. Cephalometric evaluation based on Ricketts' analysis and additional dentoalveolar variables were carried out. Statistical analysis was undertaken using a paired Student's t- and Wilcoxon signed ranks tests. The method of predicting growth according to the VTO was, in general, valid in the untreated subjects, apart from the inclination of the lower incisors, where the proclination had been underestimated. In the treated group, the net effects of treatment were significant for the dentoalveolar variables: reduction of overjet (OJ) and OB, proclination and relative intrusion of the lower incisors, extrusion of the molars, and increase in lower face height. The growth prediction method according to VTO was found to be valid in a sample of Swedish post-normal children concerning skeletal and dentoalveolar variables. The VAST treatment net effects in these growing patients were achieved mainly by dentoalveolar changes. PMID:18832190

  2. CALCULATION ASSESSMENT OF ANCHORAGE IN CONCRETE FOR FIBERGLASS REINFORCEMENT MANUFACTURED IN THE REPUBLIC OF BELARUS

    Directory of Open Access Journals (Sweden)

    E. Ya. Sadin

    2016-01-01

    Full Text Available The paper analyzes advantages and disadvantages of composite reinforcement while reinforcing concrete structures. Results of experimental investigations on adhesion strength of fiberglass reinforcement manufactured in the Republic of Belarus with concrete have been given in the paper. The paper contains an analysis pertaining to the influence of concrete contact diameter and length of fiberglass reinforcing bars on strength and deformability of adhesion with concrete. Failure behavior of prototypes and maximum loading that does cause breakage in adhesion of fiberglass reinforcement with the concrete have been controlled in order to study the influence of diameter and length of fiberglass reinforcing bar contact with the concrete on strength and deformability of concrete adhesion for composite reinforcement produced by various manufacturers. Displacement of non-loaded (free and loaded ends of the reinforcing bars with regard to concrete exposed face on both specimen ends has been also controlled. The experiments have shown that destruction of the prototypes occurred due to initiation of one of the following three reasons: reinforcement sliding in reference to concrete, cleaving of a protective concrete layer or breakage of composite reinforcement. Start-up moments for reinforcing bar slip in relation to the concrete have been determined with the help of two methods. The paper provides proposals for calculation assessment of anchorage in the concrete for fiberglass reinforcement manufactured by the following enterprises and companies “Stroykompozit” (Gomel, Republic of Belarus, Research and Production Company (RPC “Biznes-Kontinent” (Brest, Republic of Belarus and Private Eenterprise (PE “Minplast” (Minsk, Republic of Belarus.

  3. Recorded earthquake responses from the integrated seismic monitoring network of the Atwood Building, Anchorage, Alaska

    Science.gov (United States)

    Celebi, M.

    2006-01-01

    An integrated seismic monitoring system with a total of 53 channels of accelerometers is now operating in and at the nearby free-field site of the 20-story steel-framed Atwood Building in highly seismic Anchorage, Alaska. The building has a single-story basement and a reinforced concrete foundation without piles. The monitoring system comprises a 32-channel structural array and a 21-channel site array. Accelerometers are deployed on 10 levels of the building to assess translational, torsional, and rocking motions, interstory drift (displacement) between selected pairs of adjacent floors, and average drift between floors. The site array, located approximately a city block from the building, comprises seven triaxial accelerometers, one at the surface and six in boreholes ranging in depths from 15 to 200 feet (???5-60 meters). The arrays have already recorded low-amplitude shaking responses of the building and the site caused by numerous earthquakes at distances ranging from tens to a couple of hundred kilometers. Data from an earthquake that occurred 186 km away traces the propagation of waves from the deepest borehole to the roof of the building in approximately 0.5 seconds. Fundamental structural frequencies [0.58 Hz (NS) and 0.47 Hz (EW)], low damping percentages (2-4%), mode coupling, and beating effects are identified. The fundamental site frequency at approximately 1.5 Hz is close to the second modal frequencies (1.83 Hz NS and 1.43 EW) of the building, which may cause resonance of the building. Additional earthquakes prove repeatability of these characteristics; however, stronger shaking may alter these conclusions. ?? 2006, Earthquake Engineering Research Institute.

  4. Combining oxygen plasma treatment with anchorage of cationized gelatin for enhancing cell affinity of poly(lactide-co-glycolide).

    Science.gov (United States)

    Shen, Hong; Hu, Xixue; Yang, Fei; Bei, Jianzhong; Wang, Shenguo

    2007-10-01

    Surface characteristics greatly influence attachment and growth of cells on biomaterials. Although polylactone-type biodegradable polymers have been widely used as scaffold materials for tissue engineering, lack of cell recognition sites, poor hydrophilicity and low surface energy lead to a bad cell affinity of the polymers, which limit the usage of polymers as scaffolds in tissue engineering. In the present study, surface of poly (L-lactide-co-glycolide) (PLGA) was modified by a method of combining oxygen plasma treatment with anchorage of cationized gelatin. Modification effect of the method was compared with other methods of oxygen plasma treatment, cationized gelatin or gelatin coating and combining oxygen plasma treatment with anchorage of gelatin. The change of surface property was compared by contact angles, surface energy, X-ray photoelectron spectra (XPS), attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM) measurement. The optimum oxygen pretreatment time determined by surface energy was 10 min when the power was 50 W and the oxygen pressure was 20 Pa. Analysis of the stability of gelatin and cationized gelatin anchored on PLGA by XPS, ATR-FTIR, contact angles and surface energy measurement indicated the cationized gelatin was more stable than gelatin. The result using mouse NIH 3T3 fibroblasts as model cells to evaluate cell affinity in vitro showed the cationized gelatin-anchored PLGA (OCG-PLGA) was more favorable for cell attachment and growth than oxygen plasma treated PLGA (O-PLGA) and gelatin-anchored PLGA (OG-PLGA). Moreover cell affinity of OCG-PLGA could match that of collagen-anchored PLGA (AC-PLGA). So the surface modification method combining oxygen plasma treatment with anchorage of cationized gelatin provides a universally effective way to enhance cell affinity of polylactone-type biodegradable polymers. PMID:17618682

  5. Intrusão dentária utilizando mini-implantes Orthodontic intrusion with mini-implant anchorage

    Directory of Open Access Journals (Sweden)

    Telma Martins de Araújo

    2008-10-01

    Full Text Available INTRODUÇÃO: dentre os diversos tipos de movimentos dentários induzidos ortodonticamente, o de intrusão é, sem dúvida, um dos mais difíceis de serem conseguidos. A mecânica intrusiva convencional, apesar de viável, é complexa, no que diz respeito ao controle de seus efeitos colaterais. Isso, em grande parte, refere-se à dificuldade em se obter uma ancoragem satisfatória. Neste contexto, os mini-implantes, por oferecerem efetiva ancoragem esquelética, têm se mostrado de extrema valia para os ortodontistas, tornando a intrusão, tanto de dentes anteriores quanto posteriores, um procedimento cada vez mais simples, do ponto de vista mecânico. OBJETIVO: pretende-se, então, neste artigo, descrever e demonstrar, clinicamente, as diversas possibilidades de utilização dos mini-implantes como recurso de ancoragem para o movimento de intrusão.INTRODUCTION: Among all different varieties of orthodontically induced tooth movement, intrusion is, without doubt, one of the most difficult movements to be reached. Conventional intrusive biomechanics, although possible, may lead to undesirable side-effects. These events, in most cases, are related to the difficulty in obtaining an efficient anchorage unit. Then, mini-implants, because of their high success rates of effective skeletal anchorage, are valuable devices to orthodontists, transforming the intrusion movement, both at the anterior and the posterior regions, a more and more uncomplicated biomechanical procedure. AIM: to describe and show, clinically, different ways of using mini-implants as an anchorage system to intrusion movement.

  6. Spheroid Culture of Head and Neck Cancer Cells Reveals an Important Role of EGFR Signalling in Anchorage Independent Survival.

    Science.gov (United States)

    Braunholz, Diana; Saki, Mohammad; Niehr, Franziska; Öztürk, Merve; Borràs Puértolas, Berta; Konschak, Robert; Budach, Volker; Tinhofer, Ingeborg

    2016-01-01

    In solid tumours millions of cells are shed into the blood circulation each day. Only a subset of these circulating tumour cells (CTCs) survive, many of them presumable because of their potential to form multi-cellular clusters also named spheroids. Tumour cells within these spheroids are protected from anoikis, which allows them to metastasize to distant organs or re-seed at the primary site. We used spheroid cultures of head and neck squamous cell carcinoma (HNSCC) cell lines as a model for such CTC clusters for determining the role of the epidermal growth factor receptor (EGFR) in cluster formation ability and cell survival after detachment from the extra-cellular matrix. The HNSCC cell lines FaDu, SCC-9 and UT-SCC-9 (UT-SCC-9P) as well as its cetuximab (CTX)-resistant sub-clone (UT-SCC-9R) were forced to grow in an anchorage-independent manner by coating culture dishes with the anti-adhesive polymer poly-2-hydroxyethylmethacrylate (poly-HEMA). The extent of apoptosis, clonogenic survival and EGFR signalling under such culture conditions was evaluated. The potential of spheroid formation in suspension culture was found to be positively correlated with the proliferation rate of HNSCC cell lines as well as their basal EGFR expression levels. CTX and gefitinib blocked, whereas the addition of EGFR ligands promoted anchorage-independent cell survival and spheroid formation. Increased spheroid formation and growth were associated with persistent activation of EGFR and its downstream signalling component (MAPK/ERK). Importantly, HNSCC cells derived from spheroid cultures retained their clonogenic potential in the absence of cell-matrix contact. Addition of CTX under these conditions strongly inhibited colony formation in CTX-sensitive cell lines but not their resistant subclones. Altogether, EGFR activation was identified as crucial factor for anchorage-independent survival of HNSCC cells. Targeting EGFR in CTC cluster formation might represent an attractive anti

  7. 微种植体初期稳定性的影响因素%Factors affecting primary stability of mini-implant anchorage

    Institute of Scientific and Technical Information of China (English)

    鲁颖娟; 常少海

    2013-01-01

    Mini implant anchorage for the orthodontic treatment is an effective method, the primary stability is critical in the achievement of reliable anchorage. Therefore, it is the purpose of this review to summarize the cur-rent literature on the primary stability of mini-implant anchorage, in order to improve overall implant success.%  微种植体支抗技术是正畸治疗中一种有效和理想的方法,其初期稳定性是获得可靠支抗的必要条件。本文就影响微种植体支抗初期稳定性的患者因素、微种植体因素和操作因素等研究进展作一综述,以提高微种植体支抗的成功率。

  8. 种植体支抗在正畸临床上的应用%Implant Anchorage in Orthodontic Clinical Application

    Institute of Scientific and Technical Information of China (English)

    刘丽梅

    2015-01-01

    目的:探讨种植体支抗在正畸临床治疗。方法对20例种植体支抗的正畸治疗应用方法及临床应用体会。结果20例种植体支抗,微镙钉种植16例,钛板种植体3例,修复种植体1例。种植体均保持了稳定,种植体周围软组织健康,脱落率10%。结论牙齿的缺失造成支抗的不足,某些类型的牙齿移动难以或不能完成。将钛合金牙种植体作为支抗完成正畸治疗,正畸治疗结束后,将种植体行永久性修复。%Objective To investigate the implant anchorage in orthodontic clinical treatment. Methods 20 cases of implant anchorage orthodontic treatment application methods and clinical application experience. Results 20 cases of implant anchorage, micro screws planting 16 cases, 3 cases of titanium implants , implant restoration one case . Implants have maintained a stable implant soft tissue health, loss rate of 10%. Conclusion The lack of teeth caused by lack of anchorage, and certain types of tooth movement difficult or impossible to complete. The titanium dental implants as orthodontic anchorage is completed, after the end of orthodontic treatment, the implant permanently repair the line, traditional dental implant anchorage to be more widely used in orthodontic patients with a combination therapy of implant restoration.

  9. Bst1 is required for Candida albicans infecting host via facilitating cell wall anchorage of Glycosylphosphatidyl inositol anchored proteins

    Science.gov (United States)

    Liu, Wei; Zou, Zui; Huang, Xin; Shen, Hui; He, Li Juan; Chen, Si Min; Li, Li Ping; Yan, Lan; Zhang, Shi Qun; Zhang, Jun Dong; Xu, Zheng; Xu, Guo Tong; An, Mao Mao; Jiang, Yuan Ying

    2016-01-01

    Glycosylphosphatidyl inositol anchored proteins (GPI-APs) on fungal cell wall are essential for invasive infections. While the function of inositol deacylation of GPI-APs in mammalian cells has been previously characterized the impact of inositol deacylation in fungi and implications to host infection remains largely unexplored. Herein we describe our identification of BST1, an inositol deacylase of GPI-Aps in Candida albicans, was critical for GPI-APs cell wall attachment and host infection. BST1-deficient C. albicans (bst1Δ/Δ) was associated with severely impaired cell wall anchorage of GPI-APs and subsequen unmasked β-(1,3)-glucan. Consistent with the aberrant cell wall structures, bst1Δ/Δ strain did not display an invasive ability and could be recognized more efficiently by host immune systems. Moreover, BST1 null mutants or those expressing Bst1 variants did not display inositol deacylation activity and exhibited severely attenuated virulence and reduced organic colonization in a murine systemic candidiasis model. Thus, Bst1 can facilitate cell wall anchorage of GPI-APs in C. albicans by inositol deacylation, and is critical for host invasion and immune escape. PMID:27708385

  10. Remains of the ancient ports and anchorage points at Miyani and Visawada, on the west coast of India: A study based on underwater investigations

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh; Tripati, S.

    as an excellent natural harbour. The important antiquities include varieties of stone anchors, which are very similar to those reported from Dwarka and Bet Dwarka. The identification of ancient anchorage points between water depth of 5 and 15 m is another...

  11. Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2

    NARCIS (Netherlands)

    Vormer, Tinke L; Foijer, Floris; Wielders, Camiel L C; te Riele, Hein

    2008-01-01

    Mouse embryonic fibroblasts (MEFs) deficient for pocket proteins (i.e., pRB/p107-, pRB/p130-, or pRB/p107/p130-deficient MEFs) have lost proper G(1) control and are refractory to Ras(V12)-induced senescence. However, pocket protein-deficient MEFs expressing Ras(V12) were unable to exhibit anchorage-

  12. DIRECT USAGE OF MINISCREW ANCHORAGE TO INTRUDE OVERERUPTED MAXILLARY POSTERIOR TEETH BEFORE PROSTHODONTIC PREPARATION:A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Yasemin Bahar Acar

    2016-01-01

    Full Text Available Overeruption of maxillary molars due loss of opposing teeth creates occlusal and functional interferences. Before reconstruction can be initiated, intrusion of overerupted molars becomes essential. This report illustrates treatment of overerupted maxillary premolar and molar via direct use of miniscrew anchorage. A 24-year old female had lost first and second left mandibular molars due to pulpal necrotizing agents, resulting with a large alveolar bone defect and overerupted maxillary premolar and molar. She had a history of unsuccessful alveolar distraction of mandibular left premolars to increase the alveolar bone height prior to implant placement. Patient was satisfied with her smile and refused comprehensive orthodontic treatment. Maxillary premolar and molar were intruded segmentally for 4mm in 8 months, using a combination of a mini-implant and partialfixed edgewise appliances. Biological responses of teeth and surrounding bony structures to intrusion appeared normal and acceptable in radiographic and clinical examination.

  13. Anchorage of TiO2-blasted, HA-coated, and machined implants: an experimental study with rabbits

    DEFF Research Database (Denmark)

    Gotfredsen, K; Wennerberg, A; Johansson, C;

    1995-01-01

    The purpose of this study was to evaluate the histometrical and biomechanical anchorage of TiO2-blasted implants and TiO2-blasted implants coated with hydroxyapatite. The control implants were machined. Twenty-six rabbits had a total of 156 implants placed in the proximal part of the tibia. Each...... rabbit had a machined, a TiO2-blasted, and a TiO2-blasted, HA-coated implant placed in each tibia. After a healing period of 3 and 12 weeks, respectively, the implants placed in the right tibia were used for removal torque test, and the implants placed in the left tibia were used for histomorphometrical...

  14. [Low-cost simple anchorage systems in the removable hybrid prosthesis. Locator Root Attachment and Würzburg post].

    Science.gov (United States)

    Teubner, Eckart; Galindo, Martha L; Arnold, Dario; Marinello, Carlo P

    2009-01-01

    For a simple and provisional retention of a removable prosthesis, less expensive direct retainers are an option compared to indirect cast gold copings with attachment. The Dalbo-Rotex-retainer and the Ticap-system are clinically established. The Locator Root attachment and the Würzburger Stift were recently introduced. The Locator Root attachment uses a massive profiled cylindrical post as a radicular anchorage. The Würzburger Stift has a small endodontic part which is retained by four spreadable lamellae in a convergent cavity. They further differ in the design of the male and female part. Depending on the clinical situation these characteristics can offer benefits and disadvantages. Both systems are documented and their indication, advantages and restrictions are discussed with clinical relevance. PMID:20112639

  15. Dexamethasone and zinc in combination inhibit the anchorage-independent growth of S-91 Cloudman murine melanoma

    International Nuclear Information System (INIS)

    Zinc inhibited the colony formation of Cloudman S-91 murine melanoma cells in a dose dependent manner with an ID50 of 3.4 μg/ml. Total inhibition of the melanoma colony-forming units occurred at a zinc concentration of 4.42 μg/ml. In the presence of dexamethasone the ID50 for zinc inhibition was reduced by 49% and total inhibition of anchorage-independent growth occurred at the achievable in vivo zinc concentration of 3.0 μg/ml. Dexamethasone and zinc in combination effected a greater than additive inhibition of the murine melanoma colony-forming units. Statistical evaluation of these results showed that zinc and dexamethasone interacted synergistically to inhibit the formation of murine melanoma colonies. 29 references, 1 figure, 1 table

  16. A Study of the system control model of caisson dewatering of the north anchorage of Taizhou Bridge

    Institute of Scientific and Technical Information of China (English)

    Zhao Yanrong; Zhou Zhifang; Ruan Jing

    2011-01-01

    A caisson foundation is applied to the north anchorage of Taizhou Yangtze River Highway Bridge of which the initial caisson sinking requires dewatering. Since the caisson foundation is quite close to nearby buildings, a system control model is established with source (sink) distribution and intensity being the object function, minimum requirements of settlement and deformation of surroundings caused by dewatering and dynamic water levels during different working procedures being constraints, and the design parameter of pumping wells being the variable, so as to lower the jeopardizing of surrounding buildings, which provides a new method for active control over settlement during dewatering. Such a method of dewatering based on system control model should be of significance for similar projects involving dewatering.

  17. [Low-cost simple anchorage systems in the removable hybrid prosthesis. Locator Root Attachment and Würzburg post].

    Science.gov (United States)

    Teubner, Eckart; Galindo, Martha L; Arnold, Dario; Marinello, Carlo P

    2009-01-01

    For a simple and provisional retention of a removable prosthesis, less expensive direct retainers are an option compared to indirect cast gold copings with attachment. The Dalbo-Rotex-retainer and the Ticap-system are clinically established. The Locator Root attachment and the Würzburger Stift were recently introduced. The Locator Root attachment uses a massive profiled cylindrical post as a radicular anchorage. The Würzburger Stift has a small endodontic part which is retained by four spreadable lamellae in a convergent cavity. They further differ in the design of the male and female part. Depending on the clinical situation these characteristics can offer benefits and disadvantages. Both systems are documented and their indication, advantages and restrictions are discussed with clinical relevance.

  18. Characterization of the aspects of osteoprogenitor cell interactions with physical tetracalcium phosphate anchorage on titanium implant surfaces

    International Nuclear Information System (INIS)

    Well-designed implants are used not only to modify the geometry of the implant but also to change the chemical properties of its surfaces. The present study aims to assess the biofunctional effects of tetracalcium phosphate (TTCP) particles as a physical anchor on the implant surface derived through sandblasting. The characteristics of the surface, cell viability, and alkaline phosphatase (ALP) activity toward osteoprogenitor cells (D1) were obtained. D1 cells were cultured on a plain surface that underwent sandblasting and acid etching (SLA) (control SLA group) and on different SLA surfaces with different anchoring TTCP rates (new test groups, M and H). The mean anchoring rates were 57% (M) and 74% (H), and the anchored thickness was estimated to range from 12.6 μm to 18.3 μm. Compared with the control SLA surface on Ti substrate, the new test groups with different TTCP anchoring rates (M and H) failed to improve cell proliferation significantly but had a well-differentiated D1 cell phenotype that enhanced ALP expression in the early stage of cell cultures, specifically, at day 7. Results suggest that the SLA surface with anchored TTCP can accelerate progenitor bone cell mineralization. This study shows the potential clinical application of the constructed geometry in TTCP anchorage on Ti for dental implant surface modification. - Highlights: • TTCP (tetracalcium phosphate) as a physical anchorage on implant is characterized. • Theoretical values of anchored thickness and capping areas were estimated. • TTCP anchored by sandblasting can accelerate progenitor bone cell mineralization. • TTCP anchored on SLA (sandblasting and acid etching) surface is a promising method

  19. Characterization of the aspects of osteoprogenitor cell interactions with physical tetracalcium phosphate anchorage on titanium implant surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Chia-Ling [Advanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan (China); Dental Medical Devices and Materials Research Center, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan (China); Chang, Ya-Yuan; Liou, Cian-Hua [Alliance Global Technology Co., Ltd., Kaohsiung Medical Device Special Zone in Southern Taiwan Science Park, Kaohsiung 82151, Taiwan (China); Chen, Wen-Cheng, E-mail: wencchen@fcu.edu.tw [Advanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan (China)

    2015-04-01

    Well-designed implants are used not only to modify the geometry of the implant but also to change the chemical properties of its surfaces. The present study aims to assess the biofunctional effects of tetracalcium phosphate (TTCP) particles as a physical anchor on the implant surface derived through sandblasting. The characteristics of the surface, cell viability, and alkaline phosphatase (ALP) activity toward osteoprogenitor cells (D1) were obtained. D1 cells were cultured on a plain surface that underwent sandblasting and acid etching (SLA) (control SLA group) and on different SLA surfaces with different anchoring TTCP rates (new test groups, M and H). The mean anchoring rates were 57% (M) and 74% (H), and the anchored thickness was estimated to range from 12.6 μm to 18.3 μm. Compared with the control SLA surface on Ti substrate, the new test groups with different TTCP anchoring rates (M and H) failed to improve cell proliferation significantly but had a well-differentiated D1 cell phenotype that enhanced ALP expression in the early stage of cell cultures, specifically, at day 7. Results suggest that the SLA surface with anchored TTCP can accelerate progenitor bone cell mineralization. This study shows the potential clinical application of the constructed geometry in TTCP anchorage on Ti for dental implant surface modification. - Highlights: • TTCP (tetracalcium phosphate) as a physical anchorage on implant is characterized. • Theoretical values of anchored thickness and capping areas were estimated. • TTCP anchored by sandblasting can accelerate progenitor bone cell mineralization. • TTCP anchored on SLA (sandblasting and acid etching) surface is a promising method.

  20. Mechanical behavior experiment of wedge-bond anchorage for CFRP-tendons%CFRP筋复合型锚具的受力性能试验

    Institute of Scientific and Technical Information of China (English)

    王军; 李明君; 蔡东升; 刘德鑫

    2012-01-01

    In order to investigate the influence of main design parameters on anchorage performance and internal stress distribution of wedge-bond anchorage for CFRP tendons, five groups of parameter tests on wedge-bond anchorage were designed. The ultimate load, slip deformation of anchor ring and stress of metal sleeve stations were determined. The influence of design parameters on anchorage performance, the tress distribution and variation of metal sleeve were contrastively investigated through static loading testing. The results show that the anchorage performance with metal sleeve thickness of 2 mm, a wedge length of 65 mm, bond length of 500 mm is optimal. The anchor between wedge and metal sleeve is good without relative displacement. The tress distribution and variation of metal sleeve can reflect the internal stress distribution of anchorage, and the perk of stress curve indicates bonding failure between colloid and CFRP tendon near the observation point.%为研究CFRP筋复合型锚具的主要设计参数对锚固性能的影响及锚具内部受力情况,设计了5个复合型锚具的参数静载试验,测量了锚具的极限荷载、锚环-CFRP筋间滑移变形和金属筒测点应变,通过静载试验对比分析了各设计参数对锚固效果的影响,以及金属筒表面应力的分布情况与变化规律.研究结果表明:当金属筒壁厚为2 mm,夹片夹持长度为65 mm,粘结长度为500 mm时,锚具的锚固性能较好;夹片-金属筒间锚固良好,无滑移;金属筒应力分布与变化可反映锚具内部受力情况,测点应力曲线峰值预示该位置附近的胶体与CFRP筋间的粘结破坏.

  1. 新型锚固技术加固悬空岩体试验研究%Experiment Study on the New Anchorage Technology Reinforcing Suspended-rock

    Institute of Scientific and Technical Information of China (English)

    毛筱霏; 刘玉茜; 孙莹

    2011-01-01

    砂固预应力锚杆是一种新型的锚固技术,其锚固力是由砂体与锚杆孔壁之间的摩擦力和机械咬合力提供的,介绍了砂固预应力锚杆的构造形式及施工工艺,揭示了其工作机理,并对锚杆抗拔力进行了现场试验及理论研究,分析了锚杆抗拔力与位移的关系,以及砂体初始密度对抗拔力的影响.结果表明,此种锚杆具有优良的力学性能,完全可以满足小型岩体的加固要求,在工程支护领域中可以推广应用.%The sand-filled prestressed anchor is a new anchorage technology, and its anchorage force is actually the friction resistance and machine occlude force between sand and drill hole. The authors introduce the constitution and construction methods, and research the working mechanism of the sand-filling prestressed anchor. The anchor force test and theory of the anchor are studied. The relationship between anchorage force and displacement and the affection of original density of sand on anchorage force are analyzed. The test results indicate that the sand-filled prestressed anchor has excellent mechanics performance, and it can be satisfied the reinforced requests of minitype rock. The new technology can be widely used in supporting project.

  2. Factors influencing the anchorage strength of welded geogrid in soil%焊接土工格栅土中锚固强度的影响因素

    Institute of Scientific and Technical Information of China (English)

    徐超; 陈洪帅; 朱洪; 朱英俊; 石志龙

    2012-01-01

    A series of pull-out tests of 3 different selected types of welded geogrid buried in coarse grained soils are carried out in the present study. The anchorage strength and its influencing factors are analyzed based on the test results and according to the interaction mechanism of geogrid with soil. The results indicate that for geogrids with the same mesh size, the stronger the peel strength of a geogrid, the higher the anchorage strength in soils. The peel strength of welded geogrid is the controlling index, but not the only influencing factor to the geogrid anchorage strength in soil. The mesh size of georid and the property of soil are also of importance to the development of anchorage strength in soils.%选择3种不同规格的焊接土工格栅,完成了格栅在粗颗粒土中的一系列拉拔试验.根据试验结果和土工格栅与土的相互作用机理,分析了各种格栅在土中的锚固强度及其影响因素.结果表明:在网格尺寸相同的情况下,节点剥离强度越大,则土中锚固强度越高;焊接土工格栅的节点剥离强度是其土中锚固强度的控制指标,但非唯一影响因素,网格尺寸和填土性质也对格栅土中锚固阻力的发挥具有重要影响.

  3. Changes in strain patterns after implantation of a short stem with metaphyseal anchorage compared to a standard stem: an experimental study in synthetic bone

    Directory of Open Access Journals (Sweden)

    Jens Gronewold

    2014-03-01

    Full Text Available Short stem hip arthroplasties with predominantly metaphyseal fixation, such as the METHA® stem (Aesculap, Tuttlingen, Germany, are recommended because they are presumed to allow a more physiologic load transfer and thus a reduction of stress-shielding. However, the hypothesized metaphyseal anchorage associated with the aforementioned benefits still needs to be verified. Therefore, the METHA short stem and the Bicontact® standard stem (Aesculap, Tuttlingen, Germany were tested biomechanically in synthetic femora while strain gauges monitored their corresponding strain patterns. For the METHA stem, the strains in all tested locations including the region of the calcar (87% of the non-implanted femur were similar to conditions of synthetic bone without implanted stem. The Bicontact stem showed approximately the level of strain of the non-implanted femur on the lateral and medial aspect in the proximal diaphysis of the femur. On the anterior and posterior aspect of the proximal metaphysis the strains reached averages of 78% and 87% of the non-implanted femur, respectively. This study revealed primary metaphyseal anchorage of the METHA short stem, as opposed to a metaphyseal-diaphyseal anchorage of the Bicontact stem.

  4. 微种植体支抗在口腔正畸中的应用%Application of mini - implant anchorage in orthodontic treatment

    Institute of Scientific and Technical Information of China (English)

    侯亚男

    2011-01-01

    微种植体作为增强正畸支抗的措施获得了良好的临床效果.微种植体的植入手术简单,可提供绝对支抗,患者舒适感高.本文从微种植体的历史研究背景、作用原理、形态设计影响,植入方式和部位,临床应用,并发症及应用前景等方面进行详尽的综述.%With the rapid development of implant anchorage, the mini - implant has obtained good clinical results as one of the measures to enhance orthodontic anchorage, which has attracted wide attention. The procedure of implantation is simple, and after that the mini - implant can provide absolute anchorage and won't induce uncomfortableness for the patients. In this paper, we reviewed details of background, theory, effects of the design, style and position of the implantation, the clinical applications, the complications and the prospect.

  5. On-site tests to estimate aquifer permeability of drainage area of south caisson anchorage construction of Taizhou Bridge

    Institute of Scientific and Technical Information of China (English)

    Feng Zhaoxiang; Zhao Yanrong

    2011-01-01

    During the construction of the south caisson anchorage of Taizhou Bridge, the drainage area is located in the lower reaches of the Yangtze River and the permeability of stratums there is considerable. In order to maintain progress and guarantee safety during the sinking of the caisson, water should be drained in the initial period. Subsequently, detailed information about the aquifer permeability is required to make sure that the drainage will proceed successfully,which consequently necessitates the on-site estimation of the aquifer permeability in the drainage area. Therefore, the traditional pumping test and slug test are implemented respectively on site. The comparison of computational results of these two tests indicates that they are consistent overall. Notwithstanding, as slug test can be conducted with portable facilities in a short time and the manipulation is easy and few people need to be involved, the advantages of slug test is conspicuous compared with the traditional pumping test. It could be speculated that slug test will gain a prevalent application in the measurement of aquifer permeability in the future.

  6. 口腔正畸治疗中微型种植体支抗的使用价值%Value of micro- implant anchorage in orthodontic treatment

    Institute of Scientific and Technical Information of China (English)

    陈震春

    2011-01-01

    Objective To observe the success rate and effect of micro - implant anchorage in orthodontic treatment. Methods Totally 76 cases of needing orthodontic treatment patients, divided into experimental and control groups, experimental group using the orthodontic mini - implant anchorage method, while the control group using conventional methods of traditional orthodontics, to observe and compare their success rate and treatment. Results The test group and control group, no significant difference between general information, test group successfully planted micro - implant anchorage in 36 cases, the success rate was 97. 4% , growing successful anchorage stability is better, while the control group, 33 cases of successful a success rate of 84. 2% , lower than the experimental group, and the difference was statistically significant (P < 0. 05 ) , the experimental group molar shift less than the control group, the gap between the incisors protruding more than the control group, and the difference was statistically significant (P <0. 05). Conclusions Micro -implant anchorage than the traditional use of conventional methods with better efficacy, a higher success rate, is an ideal orthodontic treatment.%目的 观察微型种植体支抗在口腔正畸治疗中的成功率和效果.方法 选取76例需要正畸的患者,分为试验组和对照组,试验组采用微型种植体支抗的正畸方法,而对照组则采用常规的传统正畸方法,观察和对比其成功率和治疗效果.结果 试验组种植微型种植体支抗成功36例,成功率为97.4%,种植成功的支抗稳定性比较好,而对照组的成功33例,成功率为84.2%,比试验组低,且差异有统计学意义(P<0.05),试验组的磨牙移位比对照组少,上中切牙凸差距均比对照组多,差异有统计学意义(P<0.05).结论 微型种植体支抗的使用比传统的常规方法有着更好的疗效,成功率更高,是一种比较理想的正畸治疗方法.

  7. CFRP预应力筋粘结式锚固系统的抗疲劳性能%Fatigue Behavior of Bond-type Anchorage with CFRP Tendon

    Institute of Scientific and Technical Information of China (English)

    方志; 龚畅; 杨剑; 孙志刚

    2012-01-01

    CFRP预应力筋锚固系统的系统研究成果尤其是疲劳性能研究仍较少,采用疲劳试验机对以高性能活性粉末混凝土RPC作为新型粘结介质的CFRP预应力筋粘结式锚具的疲劳性能进行试验研究,CFRP预应力筋锚固系统疲劳试验采取对组装件交替施加静荷载和疲劳荷载,即用静载试验来检验组装件在经历一定次数重复荷载后的静力性能变化.试验结果表明该类锚具具有良好的抗疲劳性能,随着循环加载次数的增加,组装件之间的相对位置将趋于更加稳定的状态;循环加载过程中CFRP筋抗拉刚度略有降低,疲劳136万次与疲劳前组装件CFRP筋的抗拉刚度比值为93.7%.循环荷载作用下对粘结式锚具组装件有损伤,但当所施加的荷载未超过其极限破断力的40%时,CFRP筋与RPC之间的相对位置将保持比较稳定的状态,此时存在一定损伤的粘结式锚具组装件仍具有较好的承载能力.%The research on the anchorage system for CFRP tendons, especially about the fatigue behavior, is weak. A series of fatigue tests were conducted for the developing a bond-type anchorage system for CFRP tendon characterized with RPC as bond medium by fatigue machine under static load and fatigue load alternatively. Then the static behavior of the anchorage system, which experienced certain cycling loading, was inspected by static load test. The test result shows that (1) the new type of anchorage system has good fatigue behavior, with the increasing of cycling load times, the relative position of the parts of anchorage system at more stable status; (2) the tensile stiffness of CFRP tendons be slightly lower in loading process, after 136 million fatigue tests, it is 93.7% of that before fatigue test; (3) harm of anchorage system will occur under cyclic loading, however the relative slip is smaller between CFRP tendon and RPC under less than 40% of ultimate load, and the higher bearing capacity of harmed

  8. A Component-Based Study of the Effect of Diameter on Bond and Anchorage Characteristics of Blind-Bolted Connections.

    Directory of Open Access Journals (Sweden)

    Muhammad Nasir Amin

    Full Text Available Structural hollow sections are gaining worldwide importance due to their structural and architectural advantages over open steel sections. The only obstacle to their use is their connection with other structural members. To overcome the obstacle of tightening the bolt from one side has given birth to the concept of blind bolts. Blind bolts, being the practical solution to the connection hindrance for the use of hollow and concrete filled hollow sections play a vital role. Flowdrill, the Huck High Strength Blind Bolt and the Lindapter Hollobolt are the well-known commercially available blind bolts. Although the development of blind bolts has largely resolved this issue, the use of structural hollow sections remains limited to shear resistance. Therefore, a new modified version of the blind bolt, known as the "Extended Hollo-Bolt" (EHB due to its enhanced capacity for bonding with concrete, can overcome the issue of low moment resistance capacity associated with blind-bolted connections. The load transfer mechanism of this recently developed blind bolt remains unclear, however. This study uses a parametric approach to characterising the EHB, using diameter as the variable parameter. Stiffness and load-carrying capacity were evaluated at two different bolt sizes. To investigate the load transfer mechanism, a component-based study of the bond and anchorage characteristics was performed by breaking down the EHB into its components. The results of the study provide insight into the load transfer mechanism of the blind bolt in question. The proposed component-based model was validated by a spring model, through which the stiffness of the EHB was compared to that of its components combined. The combined stiffness of the components was found to be roughly equivalent to that of the EHB as a whole, validating the use of this component-based approach.

  9. 优化复合锚固结构与单一锚固结构抗爆性能对比试验研究%Comparative test study of blast-resistance performance of optimal composite anchorage structure and single anchorage structure

    Institute of Scientific and Technical Information of China (English)

    赵林; 曾宪明; 李世民; 林大路; 陆卫国

    2011-01-01

    The optimal composite anchorage structure is constituted by soil nail and groups of fixed-length empty holes that regular setting in the end of soil nail. Empty holes caused a weakened zone in the surrounding rock. The weakened zone is between the reinforced support structure and the surround rock. It changes the original two-medium system into three-medium system. Under the explosion condition, weakened zone is firstly deformed, cracked, crushed or densified; and at the same time, a great deal of blast energy is absorbed. Therefore, the crisis of the reinforced support structure is transferred into the weakened zone. The optimal composite anchorage structure has excellent blast-resistance. The test results of the compression test of optimal composite anchorage structure and single anchorage structure show that the particle acceleration of single anchorage structure is 2.22 times higher than that of the optimal composite anchorage structure. The dynamic strain of the former is 5.30-4.50 times higher than that of the latter. The blast-resistance of the optimal composite anchorage structure is 5.10 times higher than that of the single anchorage structure. Under the limit damage condition, the former is 4.13-3.40 times higher than that of the latter.%优化复合锚固结构是由土钉和在土钉端部系统而规律地设置的一定长度的经特殊处理的空孔段群组成.空孔群在围岩介质中造成一个弱化区,弱化区介于支护结构与围岩介质之间,将原有的二介质系统(支护结构和围岩),改变为三介质系统(支护结构、弱化区和围岩).爆炸条件下,优先由弱化区产生变形、破碎、压实或压密,同时大量吸收爆炸能,使支护结构的危机得以转移至弱化区而本身不受损.优化复合锚固结构对比单一锚固结构具有优异的抗动静载性能.因此进行对比试验,研究优化复合锚固结构及单一锚固结构的抗爆性能.试验结果表明,在支护结构产生临

  10. SHEAR LAG-DEBONDING MODEL FOR ANCHORAGE SECTION OF PRESTRESSED ANCHOR CABLE%预应力锚索锚固段的剪滞-脱黏模型

    Institute of Scientific and Technical Information of China (English)

    尤春安; 战玉宝; 刘秋媛; 孙琳琳; 王开彬

    2013-01-01

    Based on the calculating pattern of pulling prestressed anchorage body out from the base,the anchorage section can be divided into elastic region,plastic slide region and debonding region after analyzing the deformation and the damage process of the interface layer between anchorage body and grouting material,and the interfacial layer model for anchorage body and rock and soil mass is established.The theoretical solution of interfacial stress distribution was deduced by adopting the flow rule which associates with Coulomb condition.At the same time,a kind of new interface element model with properties of dilatancy and slippage is constructed; and interfacial stress distribution is calculated by two ways of numerical simulation and theoretical solution to verify the correctness of each other,so as to provide a new theoretical basis to calculate,analyze and design anchorage bodies.The results indicate that the main mechanical region is plastic slide region.So the plastic slippage state is the main state which the anchorage body usually in,so our researching and designing should be based on this state.In order to improve the anchoring force,we should improve maximum shear stress and extend the range of slip regime before the slip regime entering the debonding state.%基于预应力锚索锚固体从岩土体中拔出计算模式,通过锚固体与灌浆材料的界面界面层变形-破坏过程分析,将锚固段分为弹性区、塑性滑移区和脱黏区,建立锚固体-岩土体界面力学模型,采用与Coulomb条件关连的流动法则,导出界面应力分布的理论解;同时,构造具有剪胀和滑移特性的新型有限元界面单元,采用数值模拟的方法与界面应力分布的理论解进行相互验证,为锚固体受力的计算、分析与锚固体的设计提供理论依据.分析表明,锚固体的弹性区和脱黏区的受力较小,主要受力部分是塑性滑移区.因此,锚固体荷载的主要工况是塑性滑移状态,在研究

  11. The G Protein-Coupled Estrogen Receptor-1, GPER-1, Promotes Fibrillogenesis via a Shc-Dependent Pathway Resulting in Anchorage-Independent Growth

    Science.gov (United States)

    Magruder, Hilary T.; Quinn, Jeffrey A.; Schwartzbauer, Jean E.; Reichner, Jonathan; Huang, Allan

    2016-01-01

    The G protein-coupled estrogen receptor-1, GPER-1, coordinates fibronectin (FN) matrix assembly and release of heparan-bound epidermal growth factor (HB-EGF). This mechanism of action results in the recruitment of FN-engaged integrin α5β1 to fibrillar adhesions and the formation of integrin α5β1-Shc adaptor protein complexes. Here, we show that GPER-1 stimulation of murine 4 T1 or human SKBR3 breast cancer cells with 17β-estradiol (E2β) promotes the formation of focal adhesions and actin stress fibers and results in increased cellular adhesion and haptotaxis on FN, but not collagen. These actions are also induced by the xenoestrogen, bisphenol A, and the estrogen receptor (ER) antagonist, ICI 182, 780, but not the inactive stereoisomer, 17α-estradiol (E2α). In addition, we show that GPER-1 stimulation of breast cancer cells allows for FN-dependent, anchorage-independent growth and FN fibril formation in “hanging drop” assays, indicating that these GPER-1-mediated actions occur independently of adhesion to solid substrata. Stable expression of Shc mutant Y317F lacking its primary tyrosyl phosphorylation site disrupts E2β-induced focal adhesion and actin stress fiber formation and abolishes E2β-enhanced haptotaxis on FN and anchorage-dependent growth. Collectively, these data demonstrate that E2β action via GPER-1 enhances cellular adhesivity and FN matrix assembly and allows for anchorage-independent growth, cellular events that may allow for cellular survival, and tumor progression. PMID:25096985

  12. Elevated p21-Activated Kinase 2 Activity Results in Anchorage-Independent Growth and Resistance to Anticancer Drug–Induced Cell Death

    Directory of Open Access Journals (Sweden)

    Jerry W. Marlin

    2009-03-01

    Full Text Available p21-Activated kinase 2 (PAK-2 seems to be a regulatory switch between cell survival and cell death signaling. We have shown previously that activation of full-length PAK-2 by Rac or Cdc42 stimulates cell survival, whereas caspase activation of PAK-2 to the proapoptotic PAK-2p34 fragment is involved in the cell death response. In this study, we present a role of elevated activity of full-length PAK-2 in anchorage-independent growth and resistance to anticancer drug–induced apoptosis of cancer cells. Hs578T human breast cancer cells that have low levels of PAK-2 activity were more sensitive to anticancer drug–induced apoptosis and showed higher levels of caspase activation of PAK-2 than MDA-MB435 and MCF-7 human breast cancer cells that have high levels of PAK-2 activity. To examine the role of elevated PAK-2 activity in breast cancer, we have introduced a conditionally active PAK-2 into Hs578T human breast cells. Conditional activation of PAK-2 causes loss of contact inhibition and anchorage-independent growth of Hs578T cells. Furthermore, conditional activation of PAK-2 suppresses activation of caspase 3, caspase activation of PAK-2, and apoptosis of Hs578T cells in response to the anticancer drug cisplatin. Our data suggest a novel mechanism by which full-length PAK-2 activity controls the apoptotic response by regulating levels of activated caspase 3 and thereby its own cleavage to the proapoptotic PAK-2p34 fragment. As a result, elevated PAK-2 activity interrupts the apoptotic response and thereby causes anchorage-independent survival and growth and resistance to anticancer drug–induced apoptosis.

  13. Clinical application of mini-implant anchorage in orthodontics%钛金属微种植体钉作为支抗的临床应用

    Institute of Scientific and Technical Information of China (English)

    陈亚刚; 王兴; 吴文文

    2011-01-01

    BACKGROUND: Mini-implant anchorage is widely used in orthodontic fie Id. because it is small, easy to implant, use and remove,reliable in therapeutic effect and low cost.OBJECTIVE: To study the clinical application and effect of mini-implant anchorage in orthodontics.METHODS: The cep halo metric analysis was performed in 38 patients to compare overbite, coverage, molar relationship and thedegree of anterior adductor before and after treatment.RESULTSAHD CONCLUSION: The total number of mini-implants was 106, and allthe mini-implant anchorages weresuccessfully implanted except 3 cases required secondary operation with 5 loosen implants and one patient with loss of 2implants required re-implantation. Mini-implant anchorages make the treatment process s imple and acceptable in clinicalapplication.%背景:微种植体支抗因其体积小,植入、使用和去除简单,疗效可靠且成本低廉在正畸领域得到了广泛的应用.目的:观察分析钛金属微种植体支抗在口腔正畸中的应用效果.方法:对38例微种植体患者的投影测量分析,比较治疗前后的覆牙合、覆盖、磨牙关系和前牙内收程度等.结果与结论:微螺钉种植体植入总数106枚,除3例患者因5枚种植体松动再次手术植入,1例患者因2枚种植体脱落拒绝再次植入而改用传统支抗外,其他病例均获得了满意的治疗效果,建立了正常的前牙覆牙合、覆盖关系,患者面型得到了明显的改善.微种植体矫治过程相对简单,患者易于接受.

  14. Thermal Pollution Mathematical Model. Volume 6: Verification of Three-Dimensional Free-Surface Model at Anclote Anchorage. [environment impact of thermal discharges from power plants

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Tuann, S. Y.; Lee, C. R.

    1980-01-01

    The free-surface model presented is for tidal estuaries and coastal regions where ambient tidal forces play an important role in the dispersal of heated water. The model is time dependent, three dimensional, and can handle irregular bottom topography. The vertical stretching coordinate is adopted for better treatment of kinematic condition at the water surface. The results include surface elevation, velocity, and temperature. The model was verified at the Anclote Anchorage site of Florida Power Company. Two data bases at four tidal stages for winter and summer conditions were used to verify the model. Differences between measured and predicted temperatures are on an average of less than 1 C.

  15. Effects of the earthquake of March 27, 1964, on the Eklutna Hydroelectric Project, Anchorage, Alaska, with a section on television examination of earthquake damage to underground communication and electrical systems in Anchorage: Chapter A in The Alaska earthquake, March 27, 1964: effects on transportation, communications, and utilities

    Science.gov (United States)

    Logan, Malcolm H.; with a section on Television Examination of Earthquake Damage to Underground Communication and Electrical Systems in Anchorage by Burton, Lynn R.

    1967-01-01

    The March 27, 1964, Alaska earthquake and its associated aftershocks caused damage requiring several million dollars worth of repair to the Eklwtna Hydroelectric Project, 34 miles northeast of Anchorage. Electric service from the Eklutna powerplant was interrupted during the early phase of the March 27 earthquake, built was restored (intermittently) until May 9,1964, when the plant was closed for inspection and repair. Water for Eklutna project is transported from Eklutna Lake to the powerplant at tidewater on Knik Arm of Cook Inlet by an underwater intake connected to a 4.46-mile tunnel penstock. The primary damage caused by the earthquake was 1at the intake structure in Eklutna Lake. No damage to the power tunnel was observed. The piles-supported powerplant and appurtenant structures, Anchorage and Palmer substations, and the transmission lines suffered minor dammage. Most damage occurred to facilities constructed on un-consolidated sediments and overburden which densified and subsided during the earthquake. Structures built on bedrock experienced little or no damage. Underground communication and electrical systems in Anchorage were examined with a small-diameter television camera to locate damaged areas requiring repair. Most of the damage was concentrated at or near valley slopes. Those parts of the systems within the major slide areas of the city were destroyed.

  16. Anchorages - USACE IENC

    Data.gov (United States)

    Department of Homeland Security — These inland electronic Navigational charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  17. Based on the Theory of Queuing for the VLCC Anchorage Admeasurements Assessment of Lanshan Port%基于排队论的岚山港大型油轮锚地容量评估

    Institute of Scientific and Technical Information of China (English)

    张锡海

    2012-01-01

    为了评估拟建码头的配套锚地容量是否满足要求,应用排队论对锚地容量进行了数学建模,并利用该模型对岚山港大型油轮锚地进行了计算分析,得出该锚地容量满足到港船舶安全锚泊的需要,证明了用排队论来评估锚地容量是可行的。%In order to evaluate the anchorage admeasurements to meet the requirements of the proposed wharf,establishing the mathematical model for anchorage admeasurements according to the queuing theory, and calculating the VLCC anchorage admeasurements of Lanshan Port,the results show that the anchorage admeas- urements can meet the needs of vessels anchor safetyo It is prove using the queuing theory to assess the anchor- age admeasurements is feasible.

  18. 微型种植体支抗用于口腔正畸治疗临床分析%Micro implant anchorage in orthodontic treatment clinical analysis

    Institute of Scientific and Technical Information of China (English)

    张栋

    2014-01-01

    Objective to analyze the micro-implant anchorage in orthodontic treatment application results. Methods 60 cases of patients treated with orthodontic mini-implant anchorage implants, after correction for patients before and after correction of complications and the shifting of the implant were observed and compared. Results all of the micro-implant patients remain stable after 1 month of treatment, the front teeth have reached the normal coverage and other. in addition, the patients had no infectious complications. compared with the prior correction, the correction after three weeks and a month has shown a shift situation, but after three weeks compared with the correction, the correction after a month shifting signiifcantly, P<0.05. Conclusion micro implant anchorage in orthodontic applications, good stability, fewer complications.%目的:分析微型种植体支抗在口腔正畸治疗中应用效果。方法60例口腔正畸治疗患者植入微型种植体支抗,对患者矫正后的并发症情况和矫正前后种植体的移位情况进行观察比较。结果所有患者的微型种植体都保持稳定,治疗1个月后,前牙都达到了正常的覆盖等。此外,患者均无感染并发症。与矫正前相比,矫正后3周以及1个月都出现了移位情况,但是与矫正后3周比较,矫正后1个月移位情况明显,P<0.05。结论采用微型种植体支抗在口腔正畸中应用,稳定性好,并发症少。

  19. 铁路悬索桥大吨位隧道锚承载性能分析%Analysis on Bearing Performance of Large-tonnage Tunnel-type Anchorage of Railway Suspension Bridge

    Institute of Scientific and Technical Information of China (English)

    江南; 冯君

    2013-01-01

    丽香铁路金沙江大桥是我国首座采用大吨位隧道式锚碇的铁路悬索桥.本文采用三维弹塑性有限元方法对隧道锚的变形机理、承载能力以及围岩稳定状态进行分析.研究结果表明:在正常缆力作用下,锚碇体及周围岩体的位移均处于毫米量级,远小于悬索桥塔顶允许位移;锚碇体整体表现为以前底板为支点,锚碇体后部向上转动和整体向前滑移的变形模式;锚碇体及围岩绝大部分处于三向受压状态,只是在锚碇底端与下部围岩的接触部分,以及顶拱与边墙交界处局部范围内存在拉应力,建议在这些部位采取措施重点加强;基于超载极限分析法计算得到锚碇体的整体抗滑安全系数在9以上.有限元分析结果为铁路悬索桥隧道锚的优化设计提供了理论依据.%The Jinsha River Bridge of the Lijiang-Xianggelila Railway is the first railway suspension bridge with tunnel type anchorages of large tonnage in China.By using the three dimensional elastoplastic finite element method,the deformation mechanism & bearing capacity of the tunnel anchorage and the stability of surrounding rock were analyzed.The results show as follows:Under the action of normal cable forces,the displacements of the anchorage body and surrounding rock are in the millimeter range,which are far less than the allowable displacements of the suspension bridge tower;the deformation mode of the anchorage body includes the back part of the anchorage body turning upward with the front bottom plate as the fulcrum and the whole anchorage body sliding forward; most parts of the anchorage body and surrounding rock are in the triaxial compression state,except that the contact surface between the bottom end of the anchorage body and the under surrounding rock and,the local boundary area between the crown hog and flank wall are subjected to tensile stresses where stressed strengthening is needed;with the overload limit analysis method

  20. Stability and safety of mini-implant anchorage in orthodontic treatment%口腔正畸治疗中微型种植体支抗的稳定和安全性

    Institute of Scientific and Technical Information of China (English)

    刘洪; 牟雁东; 于晓光; 彭凤英; 李庆华; 邓富华

    2016-01-01

    BACKGROUND: Traditional orthodontic anchorage has the disadvantages of discomfort, difficult to control, affecting the appearance, and relying on patient’s close cooperation. Because of short-time clinical research and application, mini-implant anchorage has a great controversy in the orthodontic treatment. OBJECTIVE: To explore the application value of mini-implant anchorage in the orthodontic treatment. METHODS:Eighty cases undergoing the orthodontic treatment at the Center of Ophthalmology and Otolaryngology, Yaan People’s Hospital in China from January 2012 to June 2015 were enrol ed in this study. These patients were equal y randomized into test group and control group, which were subjected to mini-implant anchorage or headgear anchorage, respectively. The treatment was continued for 2 years in the two groups. RESULTS AND CONCLUSION: After the treatment, the successful rate in the test group was significantly higher than that in the control group (P 0.05), but the rate of adverse reactions was significantly lower in the test group than the control group (P 0.05)。但试验组患者的不良反应率明显低于对照组(P <0.05)。说明微型种植体支抗能够明显提高口腔正畸治疗患者的治疗效果,提高治疗成功率,降低术后感染发生率,具有较好的安全性和稳定性,具有较好的临床应用价值。

  1. Design and Analysis of Cable-pylon Anchorage Zone for Huaian Minj iang Bridge in Fuzhou%福州淮安闽江大桥索塔锚固区设计与分析

    Institute of Scientific and Technical Information of China (English)

    朱朝阳

    2016-01-01

    斜拉桥索塔锚固区受力复杂,对全桥结构安全具有重大影响。结合斜拉桥混凝土桥塔工程实例,介绍了主塔锚固区的设计思路,采用有限元软件建立实体模型研究锚固区应力分布情况和受力特性。结果表明:设置环向预应力对主塔锚固区侧壁受力改善显著,锚固齿块应力集中明显,应适当加大齿块尺寸,加强锚下配筋和横向钢筋配置。%The structure behavior of cable-pylon anchorage zone is complicated,and it has a great in-fluence on the safety of the whole bridge structure.Based on the example of cable-stayed bridge con-crete tower proj ect,the design mentality of cable-pylon anchorage zone was introduced,and the solid models was set up by using finite element software to analyze the stress distribution and mechanical characteristic of cable-pylon anchorage zone.The results show that:setting ring pre-stress can signifi-cantly improve the sidewall's stress states of cable-pylon anchorage zone,the stress concentration of anchor block lower edge is distinct,anchor block size should be increased properly and the disposition steel bar under anchorage and the transverse steel bar should be strengthened.

  2. Clinical study of stability of micro implant used as orthodontic anchorage%正畸微型种植体的临床应用研究

    Institute of Scientific and Technical Information of China (English)

    招惠珍; 殷慧; 黄纪美

    2012-01-01

    目的 微型种植体承受正畸力后的稳定性研究.方法 回顾2008年3月至2011年3月在佛山市禅城区中心医院口腔科确诊的安氏Ⅱ类错颌畸形患者26例,在上颌第二前磨牙与第一磨前牙之间的牙槽骨上植入微型种植体,用以支抗内收的上前牙.并于植入种植体后2周、6个月时摄X线头颅定位侧位片,比较加力前后变化,测量微型种植体的移位情况.结果 6个月后水平位移约为0.5mm,垂直位移平均约为0.4mm,与植入时相比具有统计学意义(P<0.05),其中微型种植体伸长者7例,占26.9%.结论 微型种植体是一种相对稳定的支抗,在承受正畸力后,会出现位置移动以及自体伸长,所以在微型种植体植入时要注意避开血管、神经丰富的区域,植入后要定期复诊.%Objective To study the stability of micro implant anchorage after orthodontic force. Methods Totally 26 patients with micro implants as the maxillary anchorage from March 2008 to March 2011 to in our hospital were included in this study. Micro implants were inserted on the maxillary alveolar between the second premolar and the first molar as a direct anchorage for anterior teeth retraction. And at 2 weeks after implant placement, 6 months, X ray skull lateral positioning, comparing changes before and after the afterburner, measuring micro - implant shifting. Results After 6 months the horizontal displacement of approximately 0. 5 mm, the average vertical displacement of approximately 0. 4mm, with statistically significant when compared to implants (P < 0. 05 ) , which mini - implant elongation in 7 cases, 26.9%. Conclusions Micro implants is a relatively stable anchorage to withstand orthodontic force, the position will be mobile and self - body stretch, so the mini - implant should pay attention to avoid the blood vessels, nerve - rich are-a, regular follow - up after implantation.

  3. Exposure to bisphenol A correlates with early-onset prostate cancer and promotes centrosome amplification and anchorage-independent growth in vitro.

    Directory of Open Access Journals (Sweden)

    Pheruza Tarapore

    Full Text Available Human exposure to bisphenol A (BPA is ubiquitous. Animal studies found that BPA contributes to development of prostate cancer, but human data are scarce. Our study examined the association between urinary BPA levels and Prostate cancer and assessed the effects of BPA on induction of centrosome abnormalities as an underlying mechanism promoting prostate carcinogenesis. The study, involving 60 urology patients, found higher levels of urinary BPA (creatinine-adjusted in Prostate cancer patients (5.74 µg/g [95% CI; 2.63, 12.51] than in non-Prostate cancer patients (1.43 µg/g [95% CI; 0.70, 2.88] (p = 0.012. The difference was even more significant in patients <65 years old. A trend toward a negative association between urinary BPA and serum PSA was observed in Prostate cancer patients but not in non-Prostate cancer patients. In vitro studies examined centrosomal abnormalities, microtubule nucleation, and anchorage-independent growth in four Prostate cancer cell lines (LNCaP, C4-2, 22Rv1, PC-3 and two immortalized normal prostate epithelial cell lines (NPrEC and RWPE-1. Exposure to low doses (0.01-100 nM of BPA increased the percentage of cells with centrosome amplification two- to eight-fold. Dose responses either peaked or reached the plateaus with 0.1 nM BPA exposure. This low dose also promoted microtubule nucleation and regrowth at centrosomes in RWPE-1 and enhanced anchorage-independent growth in C4-2. These findings suggest that urinary BPA level is an independent prognostic marker in Prostate cancer and that BPA exposure may lower serum PSA levels in Prostate cancer patients. Moreover, disruption of the centrosome duplication cycle by low-dose BPA may contribute to neoplastic transformation of the prostate.

  4. 微螺钉种植体支抗压低磨牙矫治前牙开(牙合)%Treatment of anterior open bite using miniscrew anchorage

    Institute of Scientific and Technical Information of China (English)

    寻春雷; 曾祥龙

    2010-01-01

    近些年来各种骨性支抗系统被开发并应用于临床,来完成牙齿各种类型的运动.微型种植体用于垂直支抗控制方面比传统方法有着更多的优势.本文病例通过应用自攻型微钛钉种植体支抗压低上下颌后部牙齿槽,治疗严重的骨性前牙开(牙合)畸形,证明自攻型微钛钉种植体提供垂直支抗控制的能力.本文也提示通过简单有效的骨性支抗手段,可以提供一种治疗较复杂骨性开(牙合)畸形的全新方法.%Skeletal anterior open bite is one type of the complicated malocclusions. It is critical to decrease the heights of posterior dentoalveolar reigons for successful treatment of anterior open bite.To obzain a stationary anchorage source, special designed implant and minisrew, miniplate have been developed recently in orthodontic clinic. Compared to traditional methods, mini-implant have more advantages in vertical control This report confirmed the effectiveness of miniscrew anchorage in skeletal anterior open bite treatment and showed the results of dental, skeletal and soft tissue profile treatment changes with the intrusion of posterior dentoalveolar segment.

  5. Exposure to Bisphenol A Correlates with Early-Onset Prostate Cancer and Promotes Centrosome Amplification and Anchorage-Independent Growth In Vitro

    Science.gov (United States)

    Tarapore, Pheruza; Burke, Barbara; Bracken, Bruce; Ho, Shuk-Mei

    2014-01-01

    Human exposure to bisphenol A (BPA) is ubiquitous. Animal studies found that BPA contributes to development of prostate cancer, but human data are scarce. Our study examined the association between urinary BPA levels and Prostate cancer and assessed the effects of BPA on induction of centrosome abnormalities as an underlying mechanism promoting prostate carcinogenesis. The study, involving 60 urology patients, found higher levels of urinary BPA (creatinine-adjusted) in Prostate cancer patients (5.74 µg/g [95% CI; 2.63, 12.51]) than in non-Prostate cancer patients (1.43 µg/g [95% CI; 0.70, 2.88]) (p = 0.012). The difference was even more significant in patients <65 years old. A trend toward a negative association between urinary BPA and serum PSA was observed in Prostate cancer patients but not in non-Prostate cancer patients. In vitro studies examined centrosomal abnormalities, microtubule nucleation, and anchorage-independent growth in four Prostate cancer cell lines (LNCaP, C4-2, 22Rv1, PC-3) and two immortalized normal prostate epithelial cell lines (NPrEC and RWPE-1). Exposure to low doses (0.01–100 nM) of BPA increased the percentage of cells with centrosome amplification two- to eight-fold. Dose responses either peaked or reached the plateaus with 0.1 nM BPA exposure. This low dose also promoted microtubule nucleation and regrowth at centrosomes in RWPE-1 and enhanced anchorage-independent growth in C4-2. These findings suggest that urinary BPA level is an independent prognostic marker in Prostate cancer and that BPA exposure may lower serum PSA levels in Prostate cancer patients. Moreover, disruption of the centrosome duplication cycle by low-dose BPA may contribute to neoplastic transformation of the prostate. PMID:24594937

  6. Tests for propagation characteristics of longitudinal guided waves in an anchored mining anchorage cable%锚固条件下矿用锚索中纵向导波传播特性的实验研究

    Institute of Scientific and Technical Information of China (English)

    吴斌; 方舟; 刘增华; 何存富

    2014-01-01

    实验研究了矿用锚索的锚固段长度对纵向超声导波 L(0,1)模态的衰减与群速度的影响。首先,通过简化为细直杆的钢丝中纵向超声导波的频散曲线分析了无锚固矿用锚索中该模态的传播特性。然后采用厚度振动型压电陶瓷片在水泥锚固条件下的矿用锚索中进行穿透法的实验,得出频段20-500 kHz 内 L(0,1)模态的幅值,确定了该压电陶瓷片对水泥锚固条件下的锚固矿用锚索的最佳导波检测频率为280 kHz。在此基础上,研究了280 kHz 附近频率点下L(0,1)模态的幅值与群速度随水泥锚固段长度增加的变化规律。最后,对矿用树脂锚固条件下的矿用锚索进行了穿透法的实验,该实验结果与水泥锚固条件下的锚固矿用锚索的实验结果相符合。这些实验为利用纵向超声导波测量锚固条件下矿用锚索的长度奠定了基础。%The effect of anchored length of a mining anchorage cable on amplitude attenuation and group velocity of ultrasonic longitudinal guided wave mode L(0,1)was investigated experimentally.Firstly,the propagation characteristics of ultrasonic longitudinal guided wave in a mining anchorage cable unanchored were analyzed with the dispersion curves of a steel wire simplified as a rod.Then,a piezoelectric element of thickness vibration type was used to perform a through-transmission test in a mining anchorage cable anchored with cement,and the amplitudes of L(0,1)mode were acquired in the frequency range of 20-500kHz.The piezoelectric element’s most suitable monitoring frequency for guided wave in the mining anchorage cable anchored with cement was 280kHz.Based on this result,the amplitude attenuation and group velocity variation characteristics of L(0,1)mode at several frequencies near 280kHz were studied in the mining anchorage cable with increase in anchored length.Finally,the through-transmission tests were performed in a mining anchorage

  7. 锚固条件下矿用锚索中纵向导波传播特性的实验研究%Tests for propagation characteristics of longitudinal guided waves in an anchored mining anchorage cable

    Institute of Scientific and Technical Information of China (English)

    吴斌; 方舟; 刘增华; 何存富

    2014-01-01

    实验研究了矿用锚索的锚固段长度对纵向超声导波 L(0,1)模态的衰减与群速度的影响。首先,通过简化为细直杆的钢丝中纵向超声导波的频散曲线分析了无锚固矿用锚索中该模态的传播特性。然后采用厚度振动型压电陶瓷片在水泥锚固条件下的矿用锚索中进行穿透法的实验,得出频段20-500 kHz 内 L(0,1)模态的幅值,确定了该压电陶瓷片对水泥锚固条件下的锚固矿用锚索的最佳导波检测频率为280 kHz。在此基础上,研究了280 kHz 附近频率点下L(0,1)模态的幅值与群速度随水泥锚固段长度增加的变化规律。最后,对矿用树脂锚固条件下的矿用锚索进行了穿透法的实验,该实验结果与水泥锚固条件下的锚固矿用锚索的实验结果相符合。这些实验为利用纵向超声导波测量锚固条件下矿用锚索的长度奠定了基础。%The effect of anchored length of a mining anchorage cable on amplitude attenuation and group velocity of ultrasonic longitudinal guided wave mode L(0,1)was investigated experimentally.Firstly,the propagation characteristics of ultrasonic longitudinal guided wave in a mining anchorage cable unanchored were analyzed with the dispersion curves of a steel wire simplified as a rod.Then,a piezoelectric element of thickness vibration type was used to perform a through-transmission test in a mining anchorage cable anchored with cement,and the amplitudes of L(0,1)mode were acquired in the frequency range of 20-500kHz.The piezoelectric element’s most suitable monitoring frequency for guided wave in the mining anchorage cable anchored with cement was 280kHz.Based on this result,the amplitude attenuation and group velocity variation characteristics of L(0,1)mode at several frequencies near 280kHz were studied in the mining anchorage cable with increase in anchored length.Finally,the through-transmission tests were performed in a mining anchorage

  8. 基于Mindlin解的压力型锚杆锚固段的受力分析%Mechanical analysis of anchorage segment of pressure-type cable based on the Mindlin solution

    Institute of Scientific and Technical Information of China (English)

    贺建清; 胡成兵; 张建超

    2012-01-01

    假设锚杆为与周围介质相同的材料,视锚杆作用的岩土体为弹性半空间位移体;基于Mindlin位移解,求出集中力作用下周围岩土体沿锚固体的轴向位移;根据压力型锚杆锚固段的受力状态,计算锚固体在轴向荷载作用下压缩变形,利用锚固体与周围岩土体变形协调假定,推导出锚固段轴向应力和剪应力分布的理论解.经过与已有现场试验实测数据对比分析,验证了理论解的可行性,并在此基础上讨论了相关岩土参数对锚固段轴向应力和剪应力的影响.锚杆现场试验和理论分析结果表明:压力型锚杆的锚固段所受轴向应力和剪应力与锚固力成正比;压力型锚杆的锚固段所受剪应力的分布形式受周围岩土体弹模、泊松比以及锚固体与周围岩土体界面的内摩擦角等因素的影响.其中周围岩土体的弹模影响最大.%Assuming that cable has the same material properties with the surrounding rock soil and there is a displacement in an elastic half-space occurred for the rock and soil mass reinforced with cable, axial displacement of surrounding rock soil mass along cable under anchorage force was calculated based on Mindlin displacement solution. Based on the stress state of anchorage segment of pressure-type cable, the compression deformation of anchorage body under axial load was also obtained. Theoretical solutions for the distribution of axial stress and shear stress on anchorage segment of pressure-type cable were derived on the assumption of a compatible deformation between anchorage body and surrounding rock soil mass. After comparing with the existed data of in-situ test, theoretical solutions proved to be feasible. On this basis, the influence of related mechanical parameters of rock and soil on shear stress and axial stress were discussed. Experimental and theoretical analysis results indicated that the axial normal stress and shear stress on anchorage segment of

  9. Movimentação de molares inferiores ancorados em mini-parafusos Mandibular molar uprighting, using mini-screw as anchorage

    Directory of Open Access Journals (Sweden)

    Rosana Canteras Di Matteo

    2005-08-01

    Full Text Available Freqüentemente a movimentação ortodôntica exige recursos adicionais de ancoragem. Os mini-parafusos têm-se apresentado como uma possível solução. O propósito deste trabalho foi estabelecer um método para a verticalização de molares inferiores inclinados para mesial, utilizando ancoragem em mini-parafusos colocados na região de linha oblíqüa externa da mandíbula. Foram selecionados três pacientes entre 40 a 48 anos (dois do gênero feminino, um do gênero masculino, com molares inferiores inclinados para mesial e distalmente posicionados às áreas edêntulas. Os pacientes foram tratados ortodonticamente durante um período de 6 a 12 meses, com técnica ortodôntica MD3. Mini-parafusos de titânio foram colocados bilateralmente com anestesia local. Uma incisão sobre a linha oblíqüa externa da mandíbula, medindo aproximadamente 1 cm foi realizada em cada lado, distalmente aos molares inclinados. Após descolamento muco-periosteal, mini-parafusos foram implantados e foram realizadas suturas deixando suas cabeças exteriorizadas. Uma semana após a remoção das suturas, cargas ortodônticas (entre 150 a 200 gramas/força foram aplicadas através de forças elásticas. Verificamos que alguma inflamação foi observada ao redor dos mini-parafusos, mas foi controlada com procedimentos de higienização. O procedimento cirúrgico é simples, podendo ser realizado pelo ortodontista; as formas dimensionais dos mini-parafusos são adequadas e estes são de fácil remoção após uso. Concluímos que o uso de mini-parafusos representa uma alternativa efetiva de ancoragem ortodôntica na verticalização de molares inferiores.Tooth movement frequently requires additional anchorage resources. Mini-screws have been used as a possible solution to this matter. The purpose of this study was to establish a method of mandibular molar uprighting, using mini-screw as anchorage, positioned on the mandibular external oblique line, behind and

  10. 微不锈钢种植体支抗的稳定性研究%Study on the stability of stainless miniscrew used as orthodontic anchorage

    Institute of Scientific and Technical Information of China (English)

    李永峰; 肖选队; 何站峰; 王朝彦; 孙晓爱

    2011-01-01

    Objective To study the stability of stainless steel implant used as anchorage under different force time. Methods Twenty malocclusional patients(10males,10females average age 16-18 years old)with a total forty miniscrews were examined.Miniscrews were insered on the maxillary tooth-bearing area between the second bicuspid and the first molar as a direct anchorage for anterior teeth extraction.AII the patients were divided into 2 groups.Force was activated immediately by nickel-titanium coil springs in group 1 after the insertion of the mini-screws.After 4 weeks the force was applied in group 2.the distance about the movement of the forced miniscrew were mearsured by the cephalometric radiographs at the beginning and half year later. Results In group 1,the miniscrews were tipped vertically 1.53mm and the sagittal distance of movement was 1.31mm on average.ln group 2,the distance was 0.83mm sagittally and 1.03mm vertically. Conclusion The stainless steel miniscrew could provide enough anchorage control for anterior teeth extraction. It is more stable for force exertion on after 4 weeks.%目的:分析不同施力时间对微不锈钢种植支抗稳定性的影响.方法:选择20例错牙合畸形患者(男10例,女10例),年龄16~18岁,分别将种植钉被植入每位患者上颌两侧第一前磨牙和第一磨牙区作为种植钉支抗内收前牙,共植入40颗不锈钢种植钉.男女患者按加载时间不同被随机平分为两组,实验组1:种植钉植入后便采用镍钛拉簧即刻加力,实验组2:4周后在进行加力,分别通过头颅侧位片测量种植钉加载前后半年的位移变化.然后对两个实验组进行统计学分析.结果:实验组1:种植钉在矢状向上平均移动了1.31mm,垂直向上平均移动了1.53mm.实验组2:种植钉在矢状向和垂直向的平均位移是0.83mm和1.03mm.结论:不锈钢种植钉能够为内收前牙提供稳定和可靠的支抗,植入4周后再施力更有助于种植钉的稳定.

  11. 探讨微型种植体支抗在口腔正畸中的临床应用%The Clinical Application of Micro-Implant Anchorage in Treating Orthodontics

    Institute of Scientific and Technical Information of China (English)

    方颖峰; 沈玥

    2014-01-01

    Object: To explore the clinical application of micro-implant anchorage in treating orthodontics. Methods: From January 2013 to December 2013, 50 cases orthodontics patients treated by micro-implant anchorage were observed and the effect of micro-implant anchorage was discussed. Results: Mini-implants were transplanted well with good stability, and there were no of loose and fall off occurred. Besides, the tooth arrangements were also corrected and the degrees of beautiful shape were significantly improved. Conclusions: Micro-implant anchorage in treating orthodontics showed better clinical application; simultaneously improved the tooth’s apparent, worth clinical promotion.%目的:探讨微型种植体支抗在口腔正畸中的应用和临床疗效。方法选取2013年1月至2013年12月期间在我院50例以微型种植体支抗进行口腔正畸治疗的患者作为调查对象。并探讨微型种植体支抗在口腔正畸中的作用。结果此次调查中,微型种植体均能良好植入,且植入后,微型种植体稳定性好、无松动、脱落等情况的发生。此外,患者牙齿排列也得到较好的矫正,外形美观程度有明显提升。结论微型种植体支抗在口腔正畸中可获得较好的临床应用,同时还可改善患者牙齿外观,可在临床上广泛推广。

  12. Mesialização de molares com ancoragem em mini-implantes Mesial movement of molars with mini-implants anchorage

    Directory of Open Access Journals (Sweden)

    Marcos Janson

    2008-10-01

    Full Text Available INTRODUÇÃO: é muito comum, na rotina do consultório odontológico, especialmente em Ortodontia, o paciente, após avaliar o plano de tratamento proposto, questionar sobre a possibilidade de fechamento de espaços presentes, ocasionados pela perda de dentes permanentes. O ortodontista, frente a essa questão, tem que avaliar diversos fatores, tais como a má oclusão presente, a integridade do osso e das raízes, o tempo de tratamento e a geometria do posicionamento dentário, que é o que permite avaliar se, com o fechamento dos espaços e, conseqüentemente, a perda de ancoragem dos segmentos anteriores, a finalização estará de acordo com os ideais que regem a especialidade. Com o advento dos mini-implantes, as possibilidades desta abordagem terapêutica aumentaram, pois o efeito adverso da perda de ancoragem pode ser eliminado e, com isso, o paciente pode ser beneficiado. No entanto, os outros fatores envolvidos, assim como a mecânica do movimento, requerem especial atenção. OBJETIVOS: no presente artigo serão abordados os fatores envolvidos neste tipo de tratamento, o raciocínio na tomada de decisões e os detalhes importantes que devem ser observados durante a condução da mecânica, ilustrados com casos clínicos.INTRODUCTION: It's routine, especially at the orthodontic office, the patient, after the assessment of the proposed treatment plan, answer about the possibility of closing their edentulous spaces caused by missed permanent teeth. In these situations, several factors must be evaluated, like the present malocclusion, the bone and roots integrity, the treatment time and the geometry of teeth positioning, that is what permits to assess if the loss of anchorage from the anterior segments, during the space closure, would permit the occlusion to end within the orthodontic ideals. With the mini-implants, the possibilities of this therapeutic approach have been improved, since the adverse effects are eliminated with the

  13. 微种植体支抗在安氏Ⅱ类1分类错牙合中的应用%The Application of Micro-implants Anchorage in Angle Class Ⅱ Division 1 Malocclusion

    Institute of Scientific and Technical Information of China (English)

    王铭蔚

    2012-01-01

    Angle class Ⅱ division 1 malocclusion prevalence is high. The premise of such disease to be successfully treated is the perfect anchorage control. Mini-implants anchorage provides stable anchorage effects for the orthodontic treatment, which is recognized and accepted by the majority of physicians. In practical application process, how to optimize the use of micro-implants to treatment of Angle class Ⅱ division 1 malocclusion is one of the difficulties in orthodontic.%安氏Ⅱ类1分类错牙合畸形患病率较高,正确的支抗设计和良好的支抗控制是这类错牙合获得成功矫治的前提.近年来,微种植体支抗由于为正畸治疗中提供稳定支抗效果而逐渐被广大医师认识和接受.在实际应用过程中,如何优化使用微种植体治疗安氏Ⅱ类1分类错牙合是当今正畸治疗的难点之一.

  14. 微种植体支抗压低前牙的临床与基础研究%The clinical and basic research of mini -implant anchorage for the anterior teeth intrusion

    Institute of Scientific and Technical Information of China (English)

    王亚楠; 杨四维

    2013-01-01

    The traditional methods are often not effective in intruding the anterior teeth, opening the bite and improv-ing the gummy smile during the orthodontic treatment. Mini-implant anchorage as an absolute anchorage can be im-planted into any part of the jaw. It can apply the absolute intrusion and also can produce a good clinical treatment effect. The aim of this article was to review the clinical and basic research of mini-implant anchorage for the anteri-or teeth intrusion.%  正畸临床矫治中在压低前牙,打开咬合,改善露龈笑时,传统方法对前牙施行绝对压低的效果往往不理想。微种植体支抗作为一种绝对支抗可植入颌骨任何部位,对前牙实施绝对的压低,产生良好的临床矫治效果。本文对微种植体支抗压低前牙的临床与基础研究作一综述。

  15. Stress analysis of cable-pylon anchorage zones of an arch-tower cable-stayed bridge%拱塔斜拉桥索塔锚固区应力分析

    Institute of Scientific and Technical Information of China (English)

    郝翠; 王建国; 曹新垒

    2011-01-01

    Taking an arch-tower cable-stayed bridge as the research obi ect, the spatial stress analysis of its cable-pylon anchorage zones is carried out with finite element analysis software ANSYS. Based on the stress analysis of the cable-pylon anchorage zones under different operation conditions, the features of stress distribution of the anchorage zones are summarized and the stress attenuation along the pylon height which is induced by the cable tension or pre-stress is studied. The results obtained can provide useful suggestions for the related designs.%文章以某拱塔斜拉桥为研究对象,运用有限元分析软件ANSYS对其索塔锚固区进行空间应力分析;通过索塔锚固区不同工况下的应力分析,总结了锚固区应力分布特性,并研究了锚固区应力在索力及预应力单独作用时沿高度方向的衰减情况,为相关设计给出了相应的建议.

  16. 边坡预应力锚索锚固问题研究%Research on Anchorage Problem of Prestressed anchor Cable applied to Slope

    Institute of Scientific and Technical Information of China (English)

    江爱军

    2013-01-01

    The prestressed anchorage technology is widely used in slope engineering due to its advancement ,economy and reliability.There are many failure events of slope because it is complex and prestressed anchor cable is concealed work. It analyzed influence factors of pre-stressed anchor cable based on the mode of failure of slope and the mechanism principle of prestressed anchor cable applied to slope.It pro-vided a basis for the evaluation of anchor cable structure safety and slope stability..%预应力锚固技术以其先进性、经济性、可靠性等优点,在边坡加固工程中得到了广泛应用。但边坡工程的复杂性和预应力锚索结构地下隐蔽工程的特殊性导致了边坡锚固工程失效破坏的事例屡见不鲜。在介绍边坡预应力锚索结构作用机理、破坏机理、破坏类型的基础上,分析了影响预应力锚索结构锚固效果的主要因素,为锚索结构安全检测评估与边坡稳定性评估研究提供依据。

  17. The effect of canine disimpaction performed with temporary anchorage devices (TADs before comprehensive orthodontic treatment to avoid root resorption of adjacent teeth

    Directory of Open Access Journals (Sweden)

    Farzin Heravi

    2016-04-01

    Full Text Available ABSTRACT Objective: The aim of this study was to evaluate the movement of impacted canines away from the roots of neighboring teeth before full-mouth bracket placement, performed by means of TADs to decrease undesired side effects on adjacent teeth. Methods: The study sample consisted of 34 palatally impacted canines, being 19 in the experimental group and 15 in the control group. In the experimental group, before placement of brackets, the impacted canine was erupted by means of miniscrews. In the control group, after initiation of comprehensive orthodontics, canine disimpaction was performed by means of a cantilever spring soldered to a palatal bar. At the end of treatment, volume of lateral incisors and canine root resorption were measured and compared by means of a CBCT-derived tridimensional model. Visual Analogue Scale (VAS score, bleeding on probing (BOP and gingival index (GI were recorded. Clinical success rate was also calculated. Results: The volume of root resorption of lateral teeth in the control group was significantly greater than in the experimental group (p < 0.001. At the end of treatment, VAS score, GI and BOP were not significantly different between the two groups. Conclusion: Based on our results, it seems that disimpaction of canines and moving them to the arch can be done successfully carried out with minimal side effects by means of skeletal anchorage.

  18. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

    Institute of Scientific and Technical Information of China (English)

    Julia Schultz; Peter Lorenz; Gerd Gross; Saleh Ibrahim; Manfred Kunz

    2008-01-01

    A microRNA expression screen was performed analyzing 157 different microRNAs in laser-microdissected tissues from benign melanocytic nevi (n=10) and primary malignant melanomas (n=10),using quantitative real-time PCR.Differential expression was found for 72 microRNAs.Members of the let-7 family of microRNAs were significantly downregulated in primary melanomas as compared with benign nevi,suggestive for a possible role of these molecules as tumor suppressors in malignant melanoma.Interestingly,similar findings had been described for lung and colon cancer.Overexpression of let-7b in melanoma cells in vitro downregulated the expression of cyclins D1,D3,and A,and cyclin-dependent kinase (Cdk) 4,all of which had been described to play a role in melanoma development.The effect oflet-7b on protein expression was due to targeting of 3'-untranslated regions (3'UTRs) of individual mRNAs,as exemplified by reporter gene analyses for cyclin DI.In line with its downmodulating effects on cell cycle regulators,let-7b inhibited cell cycle progression and anchorage-independent growth of melanoma cells.Taken together,these findings not only point to new regulatory mechanisms of early melanoma development,but also may open avenues for future targeted therapies of this tumor.

  19. Induction of anchorage-independent growth in primary human cells exposed to protons or HZE ions separately or in dual exposures.

    Science.gov (United States)

    Sutherland, B M; Cuomo, N C; Bennett, P V

    2005-10-01

    Travelers on space missions will be exposed to a complex radiation environment that includes protons and heavy charged particles. Since protons are present at much higher levels than are heavy ions, the most likely scenario for cellular radiation exposure will be proton exposure followed by a hit by a heavy ion. Although the effects of individual ion species on human cells are being investigated extensively, little is known about the effects of exposure to both radiation types. One useful measure of mammalian cell damage is induction of the ability to grow in a semi-solid agar medium highly inhibitory to the growth of normal human cells, termed neoplastic transformation. Using primary human cells, we evaluated induction of soft-agar growth and survival of cells exposed to protons only or to heavy charged particles (600 MeV/nucleon silicon) only as well as of cells exposed to protons followed after a 4-day interval by silicon ions. Both ions alone efficiently transformed the human cells to anchorage-independent growth. Initial experiments indicate that the dose responses for neoplastic transformation of cells exposed to protons and then after 4 days to silicon ions appear similar to that of cells exposed to silicon ions alone.

  20. Evaluation of stress patterns on maxillary posterior segment when intruded with mini implant anchorage: A three-dimensional finite element study

    Directory of Open Access Journals (Sweden)

    Nikhita Pekhale

    2016-01-01

    Full Text Available Introduction: The aim of this study is to evaluate stress and displacement effects of maxillary posterior intrusion mechanics with mini-implant anchorage by using finite element method. Materials and Methods: A computer stimulation of three-dimensional model maxilla with all teeth, PDL, bone, mini-implants, brackets, arch wire, force element, and transpalatal arch was constructed on the basis of average anatomic morphology. Finite element analysis was done to evaluate the amount of stress and its distribution during orthodontic intrusive force. Results: Increased Von Mises stress values were observed in mesio-cervical region of first molar. The middle third of second premolar and second molar and regions adjacent to force application sites also showed relatively high stress values. Minimum stress values were observed in apical region of first premolar as it is away from force application. Conclusion: Using three mini-implant and transpalatal arches, this study demonstrates that significant amount of true intrusion of maxillary molars could be obtained with lesser concentration of stresses in the apical area recorded.

  1. Induction of anchorage-independent growth in primary human cells exposed to protons or HZE ions separately or in dual exposures.

    Science.gov (United States)

    Sutherland, B M; Cuomo, N C; Bennett, P V

    2005-10-01

    Travelers on space missions will be exposed to a complex radiation environment that includes protons and heavy charged particles. Since protons are present at much higher levels than are heavy ions, the most likely scenario for cellular radiation exposure will be proton exposure followed by a hit by a heavy ion. Although the effects of individual ion species on human cells are being investigated extensively, little is known about the effects of exposure to both radiation types. One useful measure of mammalian cell damage is induction of the ability to grow in a semi-solid agar medium highly inhibitory to the growth of normal human cells, termed neoplastic transformation. Using primary human cells, we evaluated induction of soft-agar growth and survival of cells exposed to protons only or to heavy charged particles (600 MeV/nucleon silicon) only as well as of cells exposed to protons followed after a 4-day interval by silicon ions. Both ions alone efficiently transformed the human cells to anchorage-independent growth. Initial experiments indicate that the dose responses for neoplastic transformation of cells exposed to protons and then after 4 days to silicon ions appear similar to that of cells exposed to silicon ions alone. PMID:16187755

  2. Cellular Dichotomy Between Anchorage-Independent Growth Responses to bFGF and TA Reflects Molecular Switch in Commitment to Carcinogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Waters, Katrina M.; Tan, Ruimin; Opresko, Lee K.; Quesenberry, Ryan D.; Bandyopadhyay, Somnath; Chrisler, William B.; Weber, Thomas J.

    2009-11-01

    We have investigated gene expression patterns underlying reversible and irreversible anchorage-independent growth (AIG) phenotypes to identify more sensitive markers of cell transformation for studies directed at interrogating carcinogenesis responses. In JB6 mouse epidermal cells, basic fibroblast growth factor (bFGF) induces an unusually efficient and reversible AIG response, relative to 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced AIG which is irreversible. The reversible and irreversible AIG phenotypes are characterized by largely non-overlapping global gene expression profiles. However, a subset of differentially expressed genes were identified as common to reversible and irreversible AIG phenotypes, including genes regulated in a reciprocal fashion. Hepatic leukemia factor (HLF) and D-site albumin promoter-binding protein (DBP) were increased in both bFGF and TPA soft agar colonies and selected for functional validation. Ectopic expression of human HLF and DBP in JB6 cells resulted in a marked increase in TPA- and bFGF-regulated AIG responses. HLF and DBP expression were increased in soft agar colonies arising from JB6 cells exposed to gamma radiation and in a human basal cell carcinoma tumor tissue, relative to paired non-tumor tissue. Subsequent biological network analysis suggests that many of the differentially expressed genes that are common to bFGF- and TPA-dependent AIG are regulated by c-Myc, SP-1 and HNF-4 transcription factors. Collectively, we have identified a potential molecular switch that mediates the transition from reversible to irreversible AIG.

  3. 分析微螺钉种植体支抗在口腔正畸中的临床效果%Clinical Analysis of the Effect of Micro Screw Implant Anchorage in Orthodontic Treatment

    Institute of Scientific and Technical Information of China (English)

    赵嘉颖

    2015-01-01

    Objective To study the analysis of orthodontic Mini screw implant use result of anchorage.Methods According to the 82 cases of orthodontic patients in our hospital received to carry on the research analysis, these patients were grouped into control group and observation group, in al 41 cases patients, patients in the control group received orthodontic anchorage in treatment, the observation group use micro screw implant anchorage treatment, carries on the comparative analysis of orthodontic clinical effect of two groups of patients.Results The clinical observation of the patients in the treatment group the effective rate was 97.56%, the effective rate of the control group was 87.8%; the patients in the observation group were molars shift to lower than the control group, upper incisor inclination than the control group. Conclusion The use of micro screw implant anchorage has very good effect in orthodontic treatment, compared to the conventional anchorage effect is more prominent, and has great application value in clinical, it is worth to promote the use.%目的:研究分析口腔正畸使用微螺钉种植体支抗的效果。方法根据我院接收的82例口腔正畸患者来进行研究分析,将这些患者分组为对照组和观察组,均有41例患者,对照组患者接受正畸支抗治疗,观察组使用微螺钉种植支抗治疗,对两组患者的临床正畸效果进行比较分析。结果观察组患者的临床治疗有效率是97.56%,对照组的有效率是87.8%;观察组患者的磨牙移位要比对照组低,上中切牙倾角差比对照组高。结论在口腔正畸治疗时使用微螺钉种植支抗具有非常好的效果,相比常规的支抗效果更加突出,在临床具有较大的应用价值,值得推广使用。

  4. On Clinical Stability Factors Affecting Micro Implant Anchorage%影响微种植钉支抗的临床稳定性因素研究

    Institute of Scientific and Technical Information of China (English)

    包晨刚

    2014-01-01

    Objective To investigate the stability of micro implant as reinforcing anchorage method in the clinical application,at the same time to analyze the related factors of the success,to provide the reference for the clinical work in the future. Methods 53 patients were implanted 171 micro screws, observation period of 1 years,the influence of age,gender,the mandibular plane angle,periodontitis,periodontal tissue swelling history on stability of micro implant were analyzed. Results The total success rate of 53 patients with wrong micro implant was 90. 57%(48/53),the oral hygiene status,patient’ s periodontal tissue swelling,periodontitis,mandibular plane angle history are independent factors of micro implant survival rate,the effect of the age,gender and micro implant design factors on micro screw success rate had no significant difference,it was not statistically significant (P > 0. 05). Conclusion Patients with micro implant as reinforcing anchorage means should pay attention to keeping the mouth clean, physicians should design planting scheme according to the mandibular plane angle, avoid the periodontal tissue swelling occurs in order to improve the success rate of micro implant.%目的:探讨微型种植钉作为增强支抗手段在临床应用中的稳定性,同时分析影响其成功率的相关因素,为今后的临床工作提供参考.方法53例错颌患者共植入微型种植钉171枚,观察期1 a,并分析年龄、性别、下颌平面角、牙周组织肿胀、牙周炎史等因素对微型种植钉稳定性的影响.结果本组53例错颌患者的微型种植钉总成功率为90.57%(48/53),其中患者的口腔卫生状况、牙周组织肿胀、牙周炎史、下颌平面角等是微型种植钉成活率的独立影响因素,而且患者的年龄、性别以及微型种植钉的设计因素对微型种植钉成功率的影响无显著性差异,不具有统计学意义(P>0.05).结论采用微型种植钉作为增强支抗手段的患者要注意

  5. 温度对树脂锚杆锚固性能影响研究%Study on Influence of Temperature on Anchorage Performance of Resin Anchored Bolt

    Institute of Scientific and Technical Information of China (English)

    胡滨; 康红普; 林健; 蔡嘉芳; 姜鹏飞

    2012-01-01

    为了分析在靠近自燃发火区的巷道进行锚杆支护时,树脂锚杆锚固力降低的现象,采用实验室试验和数值模拟相结合的方法进行了温度对树脂锚杆锚固性能的影响研究.不同温度下树脂锚杆拉拔试验结果表明:温度对树脂锚杆锚固性能影响比较大,温度为25℃时树脂锚杆锚固力最大,随着模拟钻孔温度的升高,树脂锚杆锚固力呈现明显递减规律;运用FLAC3D有限差分程序对单根锚杆支护小范围锚固系统的数值模拟结果表明:岩体应力场与温度场之间存在一定程度上的耦合作用,在相同外载荷作用下,热源温度不同,岩体应力分布状态也不同.在上述研究基础上,指出温度变化对岩体物理力学性质以及树脂锚固剂固化反应过程都会产生一定的影响,并提出了不同温度环境下保证锚杆支护效果的技术途径.%To analyze the phenomenon that anchoring force of resin anchored bolt often decreased where rock bolting was carried out in the roadway near spontaneous combustion region, we studied the influence of temperature on anchoring performance of resin anchored bolts in this paper, by using the comprehensive research of laboratory test and numerical simulation. The results of pull-out tests of resin anchored bolts under different temperatures show that temperatures have great influence on anchorage performance of resin anchored bolt. The anchoring force is the largest when the temperature is 25 °C, and the anchoring force descends obviously with the borehole temperature increases. Additionally, FLAC3D was adopted to simulate and analyze the anchorage system of single bolt support small-scale, and the results show that the coupled multi-physics processes exist to a certain extent between the stress field and temperature field of rock mass. The stress distribution states of rock mass are different under the same external load when the temperatures of heat source are different. On the

  6. The Factors Affecting the Primary Stability of Mini-implant Anchorage%影响微种植体支抗初期稳定性的因素

    Institute of Scientific and Technical Information of China (English)

    王硕; 贺娇娇; 刘畅

    2015-01-01

    The use of mini-implants anchorage for the orthodontic and orthopedic treatment is an effec-tive and ideal method.It enlarges the treatment scope in clinic for its stability and efficiency .According to the implantation site and the quality of local bone tissue,it is essential to select the appropriate size of the mini-implants,implantation angle and implantation method for establishing adequate initial stability .Considerable researches have been done to investigate the initial stability of orthodontic mini-implants.Here is to make a review of the influencing factors of the primary stability of orthodontic mini-implants.%利用微种植体作为支抗装置进行正畸和矫形治疗是一种高效、理想的方法。微种植体支抗的应用使临床可矫治的范围大大增加。根据植入部位和局部骨组织的质量,适当选择微种植体的尺寸与植入角度和植入方式对建立足够的初期稳定性至关重要。许多学者对微种植体支抗的初期稳定性进行了临床及试验研究。该文就影响微种植体支抗初期稳定性的因素进行综述。

  7. GFRP筋与胶合木粘结锚固性能试验研究%Experimental Study on Bond-Anchorage Behavior of Glued-in GFRP Bars in Glulam

    Institute of Scientific and Technical Information of China (English)

    朱世骏; 杨会峰; 陆伟东; 刘伟庆; 凌志彬; 林诚

    2012-01-01

    通过对9个GFRP植筋胶合木试件的粘结性能试验,对植筋试件的破坏形态、破坏机理及粘结锚固性能进行了初步研究.试验结果表明:该类试件的破坏模式主要有拉拔端木材劈裂破坏、胶层剪切破坏和复合型破坏;当GFRP筋直径为16 mm,锚固长度为120 mm,180 mm,240 mm时,试件破坏荷载呈逐渐增大趋势,分别为49.50 kN,64.33 kN和84.87 kN,而粘结剪应力平均值逐渐降低;通过数据分析,发现粘结剪应力在靠近试验端10~ 30 mm范围内出现峰值,大小为均值的2~4倍;GFRP筋的有效粘结锚固长度约为锚固长度的1/2.研究表明,胶合木和GFRP植筋之间具有良好的粘结锚固性能,在木结构工程领域具有一定的应用前景;同时今后尚需开展更多试验研究和理论分析工作,以期为工程应用提供更多参考.%The failure modes, failure mechanism and bond-anchorage behavior were presented in this paper, through the bond property experiment of 9 specimens between glued-in GFRP rods and glued laminated timber (glulam). The test results show that the mainly failure modes include timber splitting near the pull-out surface , bond shear failure of glue line and the mixed failure. As the anchorage length of GFRP rods varied from 120 mm, 180 mm, and 240 mm with diameter of 16 mm, the failure loads increased with the value of 49. 5 kN, 64. 33 kN, and 84. 87 kN, respectively. While the bond shear stress decreased with the increasing of the anchorage length. By the data analysis, it is found that the peak value of the bond shear stress located at 10 ~ 30 mm from the pull-out surface, and this peak value was about 2-4 times of the mean value. The effective bond anchorage length was about half of the anchorage length. The research shows that the bond-anchorage behavior between glulam and glued-in GFRP bars is good, and it shows a good prospect in the engineering application of timber structures. More experimental and analytical

  8. 微型种植体支抗用于口腔正畸治疗中的效果观察%Effect of Mini Implant Anchorage for Orthodontic Treatment

    Institute of Scientific and Technical Information of China (English)

    王海

    2015-01-01

    Objective To observe the effect of the application of Micro Implant Anchorage in orthodontic treatment. Methods 70 cases of patients were selected, according to the method of random number will be the into the observation group and the control group and observation group with micro implant body anchorage in the treatment and control group treated by routine method and compared between the two groups effect. Results The observation group molar displacement, the upper central incisors angle difference and the difference between the upper central incisors and the central incisors were superior to the control group, and the incidence of adverse reactions was lower than the control group (P<0.05). Conclusion The application of Micro Implant Anchorage in orthodontic treatment is remarkable.%目的:观察在口腔正畸治疗中微型种植体支抗的应用效果。方法选取接受正畸治疗的患者70例,根据数字随机法将其分为观察组与对照组,观察组采用微型种植体支抗治疗,对照组采用常规方法治疗,比较两组疗效。结果观察组磨牙移位、上中切牙倾角差以及上中切牙凸距差等方面均优于对照组,且不良反应发生率低于对照组(P<0.05)。结论口腔正畸治疗中微型种植体支抗的应用效果显著。

  9. Simplified calculation method of concrete tower wall for steel anchor beam anchorage zone in pylon%钢锚梁索塔锚固区混凝土塔壁简化计算方法

    Institute of Scientific and Technical Information of China (English)

    贺国栋; 石雪飞

    2014-01-01

    通过对钢锚梁索塔锚固区进行构造特性分析,研究了各种构造形式下钢锚梁锚固体系的水平荷载传递途径及其分配关系。利用变形协调原理,推导了固定连接方式的锚固体系在斜拉索水平分力下钢锚梁与混凝土塔壁的荷载分配计算公式。通过简化计算,推导了水平荷载作用下混凝土塔壁控制截面的内力计算公式。将简化计算公式计算结果与有限元分析进行对比,其误差较小。这表明本研究提出的简化框架计算方法具有一定的工程意义。%By analyzing the structure characteristics of steel anchor beam anchorage zone,the load transfer pathways and distribution relationships of steel anchor beam an-chorage system under various structural forms are studied.And by using the deformation compatibility principle,the load distribution formula of fixed connection anchorage sys-tem under the horizontal component of cable force are derived.The simplified calculation formula is deduced to calculate the internal force of the control section concrete tower wall under horizontal load.The simplified calculation formula and finite element analysis results are compared,the error is small.The simplified framework of this calculation method has a certain engineering significance.

  10. Study on Structural Forms of External Prestressing Anchorage for a Novel Continuous UHPC Box-girder Bridge%新型UHPC连续箱梁桥的体外预应力锚固构造形式研究

    Institute of Scientific and Technical Information of China (English)

    邵旭东; 张良; 张松涛; 欧阳泽卉

    2016-01-01

    针对新型UHPC连续箱梁桥的结构特点及预应力体系布置,对其腹板处体外预应力下折索进行齿块锚固研究。对独立矩形齿块进行应力分析,揭示板厚对锚固区壁板外侧“局部弯曲效应”的影响。通过拓扑优化分析构建出一个揭示齿块锚固区传力机理的简化平面杆系模型,提出两种齿块锚固区局部加强的方法。在此基础上,对UHPC箱梁桥的腹板体外预应力锚固齿块进行构造设计,对比6种不同锚固方案,分析横隔板、预应力筋齿块内转向和锚固长度对锚固区受力的影响,最终得出较为合理的体外预应力齿块锚固构造形式。%According to the characteristics of a novel continuous UHPC box-girder bridge and the lay-out of its prestressing system,the anchor block for external tendons on the web was studied.Firstly,the effect of the plate thickness on the“local bending effect”in anchorage zone was evaluated through the anal-ysis of stress in the isolated rectangular anchor block.A simplified plane linkage model was proposed through the topology optimization in order to study the force transfer mechanism in anchorage zone.More-over,two kinds of methods were developed to strengthen the anchorage zone based on the simplified mod-el.On the basis of the above research procedure,six different anchoring schemes of the anchor block for the external tendons were designed.After analyzing and comparing the performance of the different ancho-ring schemes,the effects of diaphragms,steering of prestressing tendons,and anchoring length of the an-chor block on the mechanical behavior of the anchorage zone were evaluated.Finally,a type of reasonable anchor block of the external tendons was obtained.

  11. 钢锚梁式钢-混组合索塔锚固体系设计与分析%Design and Analysis of Steel-concrete Composite Anchorage Structure with Steel Anchor Beam

    Institute of Scientific and Technical Information of China (English)

    苗通; 孙蕊鑫

    2015-01-01

    A bridge is a twin towers and double cable plane prestressed concrete girder cable -stayed bridge with a span arrangement of (130 +300 +130)m,and the tower type is inverted Y and the Steel -concrete Composite anchorage structure with Steel Anchor Beam is used to anchorage the cable of end of the tower.Among this type anchorage system,the anchor boxes have been welded on both sides of the steel anchor beam,at the same time, using steel bracket to replace traditional concrete corbel structure.In this paper,the characteristics of this kind of anchor system has been introduced and the stress situation of this kind of anchor system has been analyzed u-sing the finite element method.The research conclusion can provide a reference for the design of this type of ca-ble pylon anchorage system.%某斜拉桥主桥是一座跨径布置为(130m +300m +130m)的双塔双索面预应力混凝土梁斜拉桥,索塔采用倒 Y 型,斜拉索在桥塔端采用新型空间索面钢锚梁式钢-混组合索塔锚固体系进行锚固。该型锚固体系将锚箱焊在钢锚梁两侧,同时采用钢牛腿替换传统的混凝土牛腿结构,提高了施工速度,改善了结构受力。介绍了该种锚固体系的特点,并采用有限元方法对改型索塔锚固体系的受力情况进行了分析,可为该类型索塔锚固体系设计提供参考。

  12. Monitoring and Management System Design of the Anchorage at the Upstream of the Three Gorges Dam%三峡船闸上游锚地监控管理系统设计

    Institute of Scientific and Technical Information of China (English)

    邹金松

    2015-01-01

    The monitoring and management system construction of the anchorage at the upstream of the Three Gorges Dam Lock can raise the efficiencies of shipping lockage capacity and give full play to the benefits of waterway transportation.The current status of the safety supervision in the Three Gorges Reservoir Region is analyzed for the framework designing of the target system.Furthermore, we can design the monitoring and management system framework of the anchorage at the upstream of the Three Gorges Dam Lock and the main function modules according to the analysis of system re-quirements.This system includes four functional sub-systems,namely,monitoring data collection sub-system,navigational environment information release sub-system,anchorage status dynamic mo-nitoring sub-system,and anchorage business management sub-system.The designed system can assist in supervising the waterways,ship locks,docks and ferries in the Three Gorges Reservoir Region.%三峡船闸上游锚地监控管理系统的建设可以帮助提高船舶过闸效率,充分发挥三峡工程的通航效益。对三峡坝区的安全监管现状进行分析,设计了三峡船闸上游锚地监控管理系统的架构,根据系统主体需求对主要功能模块进行设计。该系统主要包括监控数据采集、通航环境信息发布、锚地状态动态监控和锚地业务管理等子系统。该系统可实现对三峡库区航道、船闸、码头和渡口等重点水域的监控。

  13. Model test on influence of anchorage failure to slope stability%锚索失效对边坡稳定性影响的模拟试验

    Institute of Scientific and Technical Information of China (English)

    罗强; 李亮

    2011-01-01

    The failure processes of anchorage slope in two failure modes (the arc mode and broken line) under different loads were simulated through serials of laboratory experiments.Based on the experiment simulations, the characteristics of slope stability were analyzed under the condition of various types of rock and soil slopes when anchors are out of action.The characteristics of slope reinforced by group anchor were studied in terms of mechanics and deformation.The effect of failure of anchor cables on slope stability was studied.The analysis results show that the up-row anchor cables lose the stability prior to the down-row anchor cables, and the anchor force offered by the up-row anchor cables will be switched to other anchor cables.The failure of anchor cables at different locations of slope in the arc failure mode slightly affects the slope stability, while in the broken line failure mode the locations of invalid anchor cables play significant role in slope stability.%通过多组模型的室内模拟试验,模拟了锚固边坡在不同荷载条件下沿圆弧和折线2种模式的破坏过程,分析了不同岩土体边坡锚固失效时稳定性的不同特性,以及群锚作用条件下单锚失效时边坡的力学及变形特点,进而研究了边坡锚索失效对边坡稳定性的影响机理.研究结果表明:在荷载作用下,边坡上排锚索比下排锚索先破坏,失效锚索的锚固力会向其他锚索转移;圆弧破坏边坡不同位置的锚索失效对边坡稳定的影响与锚索所在位置关系不大,而折线破坏的边坡不同位置锚索破坏对边坡稳定性的影响不同.

  14. Abduction of Toe-excavation Induced Failure Process from LEM and FDM for a Dip Slope with Rock Anchorage in Taiwan

    Science.gov (United States)

    Huang, W.-S.; Lin, M.-L.; Liu, H.-C.; Lin, H.-H.

    2012-04-01

    On April 25, 2010, without rainfall and earthquake triggering a massive landslide (200000 m3) covered a 200m stretch of Taiwan's National Freeway No. 3, killing 4 people, burying three cars and destroying a bridge. The failure mode appears to be a dip-slope type failure occurred on a rock anchorage cut slope. The strike of Tertiary sedimentary strata is northeast-southwest and dip 15˚ toward southeast. Based on the investigations of Taiwan Geotechnical Society, there are three possible factors contributing to the failure mechanism as follow:(1) By toe-excavation during construction in 1998, the daylight of the sliding layer had induced the strength reduction in the sliding layer. It also caused the loadings of anchors increased rapidly and approached to their ultimate capacity; (2) Although the excavated area had stabilized soon with rock anchors and backfills, the weathering and groundwater infiltration caused the strength reduction of overlying rock mass; (3) The possible corrosion and age of the ground anchors deteriorate the loading capacity of rock anchors. Considering the strength of sliding layer had reduced from peak to residual strength which was caused by the disturbance of excavation, the limit equilibrium method (LEM) analysis was utilized in the back analysis at first. The results showed the stability condition of slope approached the critical state (F.S.≈1). The efficiency reduction of rock anchors and strength reduction of overlying stratum (sandstone) had been considered in following analysis. The results showed the unstable condition (F.S. anchors on the stability of slope. The analysis indicated that the incremental load of anchors have similar tendency comparing to the monitoring records in toe-excavation stages. This result showed that the strength of the sliding layer was significantly influenced by toe-excavation. The numerical model which calibrated with monitoring records in excavation stage was then used to discuss the failure process

  15. Caracterização de mini-implantes utilizados na ancoragem ortodôntica Characterization of the mini-implants used to orthodontic anchorage

    Directory of Open Access Journals (Sweden)

    Luciana Rougemont Squeff

    2008-10-01

    Full Text Available INTRODUÇÃO: o diâmetro reduzido do mini-implante, e a decorrente facilidade na sua inserção, minimizam a possibilidade de erro do operador e de contato entre a rosca do mini-implante e a raiz dentária. Entretanto, o risco de fratura da peça aumenta à medida que seu diâmetro é diminuído. MÉTODOS: neste trabalho foram analisados quatro produtos de marcas nacionais (INP, SIN, Conexão e Neodente e um de marca alemã (Mondeal, com o objetivo de identificar características importantes para o bom desempenho deste recurso como acessório de ancoragem. Foram observados composição e design das peças e realizado o ensaio mecânico de torque até a fratura (estudo in vitro, cujos valores foram submetidos à análise de variância (ANOVA e teste de Tukey. RESULTADOS: os resultados mostraram que todos os mini-implantes testados estão aptos à utilização clínica como reforço de ancoragem ortodôntica.INTRODUCTION: The reduced diameter of the mini-implants and the simplicity of the technique could minimize the operator mistake's possibility and avoid the contact between the thread of the screw and the dental root. In spite of that, it increases the fracture risk because of the diameter's decrease. METHODS: At the present work, mini-implants from five different trade marks, four Brazilian systems (INP, SIN, Conexão and Neodente and a German system (Mondeal were studied to identify important characteristics of this anchorage accessory, like composition, design and resistance to the insertion torque (in vitro. The values obtained from the mechanical torque test were submitted to variance analysis (ANOVA and Tukey's test. RESULTS: All studied groups presented good results and are recommended to orthodontic clinic use.

  16. 预应力纤维布混合锚固分析与试验研究%Analysis and Testing Study of Hybrid Anchorage of Prestressed FRP

    Institute of Scientific and Technical Information of China (English)

    李青松; 孟少平; 单岗; 王侠伟

    2011-01-01

    In order to improve the deficiency in the technology of embedded prestressed FRP reinforcement, with the principle of anchoring bond and additional mechanical anchoring working together, the tensioning end of prestressed FRP is anchored twice after the tension and bonding of the FRP, then removing the existing fixture and anchor. To ensure the reliability of anchoring, the paper makes a theoretical analysis of the performance of the bonding layer in the anchoring end and an experimental research on hybrid anchoring end. The research results show that the change of the performance in the bonding layer improves its anchoring ability significantly, and the steel plate can be squeezed to provide pressure to improve and enhance the performance of the bonding layer,which guarantee the quality of anchoring end. The method of combining bonding layer with hybrid anchorage of the steel plate can provide the adequate anchoring capacity, improve the construction techniques, lessen the cost and the boost the application of prestress FRP reinforcement in the practical constructions.%为了改善嵌人式预应力纤维布(FRP)加固技术的不足之处,利用粘结与机械锚固共同工作的原理,在预应力FRP张拉粘贴完毕后,对张拉端进行二次锚固,粘结层硬化后拆除原有锚夹具.为保证锚固端的可靠性,本文对锚固端粘结层的性能进行了理论分析,并对混合锚固端进行了试验研究.研究结果表明:通过改变粘结层的性能,可大幅度提高粘结层的锚固能力;钢板压条可提供挤压力,改善和提高了粘结层的受力性能,便于保证锚同端施工质量,可靠性好.采用粘结层与钢板压条混合锚固的方式可为预应力FRP提供足够的锚固力,改善了施工工艺,明显降低加固成本,促进了预应力FRP加固技术在实际工程中的应用.

  17. 铁路矮塔斜拉桥索塔锚固区局部应力分析%Stress Analysis of Cable-pylon Anchorage Zones of Extra-dosed Cable-stayed Bridge in Railway

    Institute of Scientific and Technical Information of China (English)

    陈兴冲; 赵霆; 刘尊稳; 丁明波

    2012-01-01

    An extra-dosed cable-stayed bridge is taking as the practical engineering background to make the finite element analysis of the main tower by large software Ansys. The size and distribution of the concrete stress of the anchorage zones in 3 200 kN design loads are obtained, which verifies the security of the pylon design,enriches spatial stress analysis of the anchorage zone of extra-dosed cable-stayed bridge and plays a positive role in the design and construction of the project.%以某矮塔斜拉桥为实际工程背景,采用Ansys大型软件对其主塔进行了有限元分析.得出了在3200kN的设计荷栽作用下,其锚固区混凝土应力的大小及分布情况,验证了索塔设计的安全性,丰富了矮塔斜拉桥索塔锚固区的空间应力分析,对工程的设计与施工起到了积极作用.

  18. Multi-means sweeping measurement for anchorages of Yingkou Port and its implementation%营口港锚地多手段扫海综合测量方法及其实施

    Institute of Scientific and Technical Information of China (English)

    李冬; 杨绍海; 张永合; 任晓东

    2012-01-01

    This paper focuses on the methods and the processes of measuring underwater topography with side scan sonar, single beam and multi-beam integrated system in many anchorages of Yingkou Port. Then detecting results are compared with the data collected by artificial groping underwater. The distribution of underwater topography is also analyzed. The results of these measurements have remarkable consistency,which can provide detailed hydrologic data and effective application basis for the anchorages of Yingkou Port.%文章重点介绍了利用侧扫声呐、单波束、多波束集成系统开展营口港多个锚地水下地形探测的方法和过程,并将探测到的结果与调查收集和人工水下探摸的资料进行了比较,分析了水下地形的分布情况,不同探测方法得出的结果得到有力地互相印证,为港口锚地提供了详实的水文资料和有效的应用依据。

  19. Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate

    Directory of Open Access Journals (Sweden)

    Hsiu-Man Lien

    2011-01-01

    Full Text Available In this study, 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1 was isolated from three different sources of dried fruiting bodies of Antrodia camphorate (AC. AC is a medicinal mushroom that grows on the inner heartwood wall of Cinnamomum kanehirai Hay (Lauraceae, an endemic species that is used in Chinese medicine for its anti-tumor and immunomodulatory properties. In this study, we demonstrated that SY-1 profoundly decreased the proliferation of human colon cancer cells (COLO 205 through G0/G1 cell-cycle arrest (50–150 μM and induction of apoptosis (>150 μM. Cell-cycle arrest induced by SY-1 was associated with a significant increase in levels of p53, p21/Cip1 and p27/Kip1, and a decrease in cyclins D1, D3 and A. In contrast, SY-1 treatment did not induce significant changes in G0/G1 phase cell-cycle regulatory proteins in normal human colonic epithelial cells (FHC. The cells were cultured in soft agar to evaluate anchorage-independent colony formation, and we found that the number of transformed colonies was significantly reduced in the SY-1-treated COLO 205 cells. These findings demonstrate for the first time that SY-1 inhibits human colon cancer cell proliferation through inhibition of cell growth and anchorage-independent colony formation in soft agar. However, the detailed mechanisms of these processes remain unclear and will require further investigation.

  20. 比较种植体支抗和J钩临床效果的Meta分析%Clinical effects of implant anchorage versus J-hook headgear: A Meta-analysis

    Institute of Scientific and Technical Information of China (English)

    陈燕; 王思; 曹阳; 陈嵩

    2011-01-01

    背景:正畸治疗常用的有面弓形口外弓和J钩,两者都能很好地增强支抗,但临床效果可能有差异.目的:比较种植体支抗和J钩在临床治疗效果及牙根吸收方面的差异.方法:计算机检索PubMed(1950-01/2010-08)、Embase(1966-01/2010-08)、Cochrane library(2010年第2期)、中文科技期刊数据库(VIP)(1989-01/2010-08)、中国生物医学文献数据库(CBM)(1978-01/2010-08)、中国期刊全文数据库(CNKI)(1979-01/2010-08).手工检索并辅以文章追溯的方法收集国内、国外学者10年内公开发表的有关比较种植体支抗和J钩效果的文献.运用Meta 分析对头影测量结果进行定量分析.采用RevMan5.0版统计软件进行统计分析.采用卡方检验对纳入研究进行异质性检验.采用固定效应模型及随机效应模型,计算合并加权均数差及其95%CI.结果及结论:共纳入4篇文献,87例受试者.Meta分析结果显示:种植体组比J钩组在覆合、覆盖减少量和上中切牙切缘至腭平面的垂直距离减少量3项指标变化上差异有显著性意义.单个研究结果:相对于J钩,种植支抗引起牙根吸收量较少,结果有显著性差异.在支抗控制方面,种植体支抗可以很好的替代J钩.但是尚需要更多高质量,大样本的RCT进一步验证两者的差异.%BACKGROUND: Implant anchorage and J-hook are commonly used in orthodontic treatment, both of which can enhance the anchorage, but the effects of them may be different.OBJECTIVE: To compare the differences of implant anchorage and J-hook headgear between clinical therapeutic efficacy and root adsorption.METHODS: PubMed database (1950-01/2010-08), Embase (1966-01/2010-08), Cochrane library (the second phase, 2010), VIP database (1989-2010-08), CBM database (1978-01-2010-08), CNKI database (1979-01-2010-08) was retrieved by computer.Literatu res addressing implant anchorage and J-hook headgear effect published in 10 years by domestic and foreign scholars were

  1. Application progress of orthodontic treatment with titanium miniplate anchorage system%微钛板种植支抗在口腔正畸临床中应用进展

    Institute of Scientific and Technical Information of China (English)

    宁召亮(综述); 刘琳(审校)

    2013-01-01

    种植支抗作为多学科交流融合产物,无疑对正畸临床的诊断与治疗理念产生了巨大影响。从目前国内外对于种植支抗的关注度以及临床应用情况来看,微螺钉种植支抗将成为口腔正畸种植支抗的主要趋势。微钛板种植支抗由于其优势,如脱落率极低、固位钉远离牙根、植入时或牙齿在较大范围内移动时也不会累及牙根、临床加力简单、不依赖于患者的配合程度等,可为多种复杂错牙合畸形提供治疗选择。由于微钛板埋入手术的损伤较大,术后肿胀较明显,术后不良反应给患者带来的恐惧心理以及较高的费用均影响了微钛板支抗在正畸临床上的应用。而组织相容性好、稳定性强、简单、微创、舒适的微钛板种植支抗系统的进一步研究,必将对正畸临床诊断和治疗产生积极深远的影响。%As a product of multidisciplinary combination,the usage of implant anchorage undoubtedly had a great impact on clinical diagnosis and concept of modern orthodontic treatment. From the perspectives of both international and do-mestic interests in the clinical application of orthodontic anchorage,mini-screws anchorage implant would become a sig-nificant trend in this field. However,titanium miniplate anchorage could more efficiently offer a new choice for the treat-ment of complex maxillofacial malformation,because it had plenty of advantages that other methods did not,such as low losing ratio,retentive pin far away from tooth roots,easy applying force operation for orthodontists,tooth roots barely in-volved during implantation or obvious tooth movement,and being less dependent on patients' compliance. Inevitably, there were also several drawbacks restricting its clinical application,including the possibility of severe surgical injury, significant swelling after implantation,patients' great fear caused by side-effects and higher surgery cost. But one thing is certain

  2. Construction Technique of Dragging Stay Cables with Parallel Steel Wire Strands into Anchorages for the Second Jiujiang Changjiang River Bridge%九江二桥平行钢丝斜拉索牵引入锚施工技术

    Institute of Scientific and Technical Information of China (English)

    吴小斌; 杜俊; 李东辉

    2014-01-01

    The main bridge of the Second Jiujiang Changjiang River Bridge is a two-pylon six-span asymmetrical hybrid girder cable-stayed bridge with a main span of 818 m and with double ca-ble planes .The stay cables are composed of the φ7 mm parallel steel wires ,each having a nominal tensile strength of 1 670 MPa .By the comparative analysis of the dragging construction techniques of dragging carried out by hoisters ,soft dragging ,strong dragging and a combination of the two , it was determined to drag the stay cables via a combined application of the above dragging tech -niques ,taking into consideration of the facts that the stay cables are very heavy and long and the difference between the cable forces in the central span and the side spans are great .According to the actual characteristics of the construction ,the auxiliary facilities for the stay cables installation were prepared ,including lifting portal mounted on pylon tops and the platform used to drag the ca-bles into the anchorages on the girder ,by which the problems of the insufficient hoisting capacity and the difficult installation of the dragging devices were resolved .To improve the efficiency of stay cable installation ,the short cables were installed by the steel strand elongation method ,effec-tively reducing the dragging force in the pressing anchorages in the girder and accelerating the speed of the cable′s entering into the anchorages in the girder .The long cables were dragged into the anchorages by the soft dragging and combined application of the aforementioned methods ,re-solving the difficulty of dragging the long cables into the anchorages in the girder .%九江二桥主桥为主跨818 m 的六跨不对称双塔双索面混合梁斜拉桥,斜拉索采用平行钢丝斜拉索,钢丝直径7 mm ,抗拉强度标准值1670 MPa 。通过对卷扬机牵引、软牵引、硬牵引及软硬组合牵引等牵引施工工艺的对比分析,结合该桥的斜拉索超重超长、中边跨索

  3. 碳纤维增强复合材料筋复合型锚具试验研究和有限元分析%EXPERIMENTAL INVESTIGATION AND FINITE ELEMENT ANALYSIS OF WEDGE-BOND ANCHORAGE FOR CFRP-TENDONS

    Institute of Scientific and Technical Information of China (English)

    刘荣桂; 李明君; 刘德鑫; 蔡东升; 谢桂华

    2012-01-01

    In order to colligate the virtue of bonding-anchor and wedge-anchor, the wedge-bond anchorage for CFRP tendons was investigated, which was made by bonding and wedge parts, working in parallel. Based on the characteristics of exiting CFRP tendon anchors and according to a series of static load tests, it was studied the bonding property of colloid, and the influence of bond length, colloids thickness on the performance of straight pipe bonding anchorage. The static load test of wedge-bond anchorage was conducted to investigate its failure mode, ultimate load, slip deformation, etc. Transport mechanism of anchorage stress is preliminarily analysed according to variation of actual stress in the anchorage zone. The influences of variation in specific parameters, such as wedge slope, angular differential, presetting load, on the internal stress of the anchorage were simulated by using finite element method. And the suggested design parameters were offered. Which can provide academic reference for the optimization of wedge-bond anchorage.%为综合粘结型锚具与夹片型锚具各自的优点,在已有碳纤维增强复合材料(简称CFRP)筋锚具的基础上,研究由粘结部分与夹持部分协同工作而成的复合型锚具。由直筒粘结型锚具的静载试验,研究胶体粘结性能,粘结长度、胶体厚度对锚固性能的影响。通过复合型锚具静载试验,研究该类锚具的失效模式、极限荷载、滑移变形等,结合锚固区实测应力变化,初步分析锚固应力的传递机制。通过有限元分析方法,模拟计算夹片倾角、锥角差、预紧力等参数对复合型锚具内部受力的影响,得到建议设计参数,为复合型锚具结构优化提供参考。

  4. Mini-implant Anchorage in Orthodontic Treatment Nursing Intervention%微型种植支抗在口腔正畸治疗中的护理干预

    Institute of Scientific and Technical Information of China (English)

    龚晓琳

    2014-01-01

    Objective To summarize the micro-implant anchorage methods and ef ects of nursing interventions in orthodontic treatment. Methods Our hospital in January 2012-2013 February malocclusion treated 45 patients were given orthodontic mini-implant anchorage surgery before and after surgery have implemented measures to improve nursing intervention period was 14 days. Patient satisfaction through 9 Surgical cosmetic surgery orthodontic clinical data analysis. Results After the intervention ef ective in 34 cases, ef ective in 11 cases, the ef ective rate was 100.0%, with no serious complications and at achment loss occurs. After 14 days in patients with plaque index increased significantly, while the probing depth decreased with preoperative contrast significantly dif erent ( <0.05). Conclusion The mini implant anchorage in orthodontic treatment applied to ef ectively improve the appearance of the mouth and chewing function, but also the need to strengthen nursing intervention.%目的:总结微型种植支抗在口腔正畸治疗中的护理干预方法与效果。方法选择我院正畸科2012年1月~2013年2月收治的错颌畸形患者45例,都给予口腔正畸微型种植支抗手术治疗,在手术前后都实行了完善的护理措施,干预周期为14d。通过对患者进行临床资料分析。结果干预后显效34例,有效11例,有效率为100.0%,无严重并发症与附着丧失发生。术后14d患者的菌斑指数明显下降,而探诊深度明显下降,与术前对比差异明显(<0.05)。结论微型种植支抗在口腔正畸治疗中的应用有效改善了口腔美观及咀嚼功能,但是也需要加强护理干预。

  5. Combination application of implant and mini-screw implant as anchorage in orthodontic and renovation%种植体和微型种植体支抗在正畸与修复中的联合应用

    Institute of Scientific and Technical Information of China (English)

    武秀萍; 李冰; 冯云霞

    2013-01-01

    目的:探讨种植体和微型种植体支抗在正畸与修复中的联合应用的可行性,并观察临床效果。方法:选择24例下颌磨牙缺失对牙伸长需要做种植的患者。缺牙区植入ITI种植体,常规种植治疗。同时在对伸长的磨牙的近中腭侧和远中颊侧各植入一枚微型种植体,用橡皮链挂在颊、腭侧的种植体上,以压低伸长的对牙齿,定期更换并进行临床检查。结果:24例患者中,1枚微型种植钉松动脱落,余23例患者伸长牙平均压低2.4mm,平均压低时间为5.6个月,经种植修复后均获得满意的临床效果。结论:针对下颌磨牙缺失对牙伸长的病例,种植体和微型种植体支抗的联合应用,能达到最佳的修复效果。%Objective: To evaluate the clinical effects of combination application of implant and mini-screw implant as anchorage in orthodontic and renovation. Methods: Choose 24 patients who's mandibular molar had defected and maxillary molar had elongated>2.5mm. The patients' mandibular molar defect were received ITI implant installation under the normal treatment rules. At the same time, the extruded maxillary molar were treated with self-drillinng mini-screw implant as anchorage for intrusion. Rusults:1 patient's miniscrew implant were loosed and then lost because of peri-implant inflammation. Other 23 patients' maxillary molar were average intruded 2.4mm in 5.6 month. After ITI implant installed in par-tial edentulous area, the effect of the treatment were excellent. Conclusion: To the patients of mandibular molar defected and maxillary first molar elongated, combination application of implant and mini-screw implant as anchorage in orthodontic and renovation can obtain optimal results.

  6. Horizontal Load Distribution in the Steel Anchor Beam Anchorage Zone of a Bridge Pylon%钢锚梁索塔锚固区水平荷载分配关系

    Institute of Scientific and Technical Information of China (English)

    贺国栋; 阮欣; 石雪飞; 徐亮

    2014-01-01

    为了分析钢锚梁索塔锚固区混凝土塔壁的水平受力性能,首先必须明确索力作用下混凝土塔壁和钢锚梁分别具体承担了多少水平力。为此,研究了各种构造形式下钢锚梁锚固体系的水平荷载传递途径,表明锚固区的水平荷载分配与结构的构造形式和施工过程有关。利用变形协调原理,推导了固定连接方式的锚固体系在斜拉索水平分力下钢锚梁与混凝土塔壁的荷载分配计算公式。研究了各种构造形式下钢锚梁锚固体系的水平荷载分配具体计算方法。通过有限元计算对简化计算公式进行验证,误差约为6.5%,表明简化公式具有较好的准确性。%In order to analyze the mechanical behavior of concrete tower wall in the steel anchor beam anchor-age zone of a bridge pylon,it is interested to understand the distribution proportion between the concrete tower wall and the steel anchor beam under cable force.This paper studied the load transfer pathways and distribu-tion relationship for the steel anchor beam anchorage system under various structural forms.It was found that that the load distribution was associated with structural forms and construction processes.By using the deform-ation compatibility principle,the load distribution formula of fixed connection anchorage system under the hori-zontal component of cable force was derived.The results calculated by using this simplified formula were com-pared with the finite element result,which indicates the validity of the formula with a error of about 6.5%.

  7. Pre-stressing Effect Analysis in Cable-tower Anchorage Zone of Cable-stayed Bridge%斜拉桥桥塔拉索锚固区预应力效应分析

    Institute of Scientific and Technical Information of China (English)

    王宏祥

    2014-01-01

    斜拉桥桥塔多采用 A 型或倒 Y 型的结构形式,其索塔锚固区域处于复杂空间受力状态,普通钢筋混凝土结构已经难以满足受力要求。结合某斜拉桥索塔锚固区的混凝土拉应力超限的现象,进行合理预应力配束。建立三维 ANSYS 有限元实体模型,对施加预应力后的索塔锚固区进行局部应力分析。分析表明:合理施加预应力可以有效改善索塔锚固区的受力性能,克服了普通钢筋混凝土结构拉应力超限的问题,且预应力钢束布置并不引起桥塔的附加位移。%Type A or inverted type Y are widely adopted in the bridge towers of cable-stayed bridges ,and the cable-tower anchorage zones are under complex spatial stress .Based on a cable-stayed bridge whose concrete tension stress in its ca-ble-tower anchorage zone is beyond the limits ,the pre-stressed steel bars were reinforced rationally .Then ,the finite ele-ment model is established by using ANSYS so as to analyze the local stress state of the cable-tower anchorage zone after prestressing .The results indicate that the reasonable layout of the pre-stressed steel in cable-tower zone could effectively improve the local mechanical behavior ,and overcome the phenomenon that the concrete tension stress is beyond the lim-its .Moreover ,the layout of the pre-stressed steel would not cause the additional displacement of the bridge pylon .

  8. 微型种植体骨性支抗在临床的应用研究%The application and research of micro-implant bone anchorage in clinic

    Institute of Scientific and Technical Information of China (English)

    苏丽英; 刘国实; 王松梅; 张宏; 卢晓梅; 陈竟男; 夏国栋; 李光磊

    2011-01-01

    [目的]探讨微型自攻型钛种植体作为骨性支抗在临床正畸工作中的应用及其优、劣势.[方法]20例患者应用48颗微型种植体,用于拉前牙向后,关闭拔牙间隙时植入第2前磨牙与第1磨牙之间牙槽间隔,单侧磨牙缺失时植入第2磨牙的远中,需直立后牙者置于该牙齿的倾斜方向反向颊侧.微型种植体植入后可即刻加力,承受的牵动力为100~200 g.[结果]安氏Ⅱ类骨性上颌突、双颌突病例12例治疗结束后,切牙切缘平均内收6.3~6.4 mm,支抗磨牙平均前移0.3~0.4mm,单侧恒磨牙缺失的病例磨牙支抗前移1.0~1.5 mm,面型均得到明显的改善.安氏I类、安氏Ⅲ类错(牙合)病例的治疗均达到理想效果.[结论]自攻型微钛钉种植体作为骨性支抗具有接触面积小、稳定性强、力量强的优点;种植后即刻加力,缩短了疗程;正畸医师可以独立完成操作,患者也易于接受.%[Objective] To study the self-drilling titanium screw mini-implants as skeletal anchorage in the clinical application of orthodontic work, study its advantages and disadvantages. [Methods] 20 patients treated with 48 micro-implant for anterior teeth pulled back. Implanted at the time extraction space closed second premolar and the first molar alveolar interval, when the unilateral molar implant distal second molar, to be placed upright in the posterior teeth by reversing the direction of tilt of the cheek teeth side. Micro-implants after immediate loading, will affect the force to withstand 100~200 g. [Results] Class II skeletal maxillary protrusion, bimaxillary protrusion cases of 12 patients after treatment, the average margin of incisors adductor 6.3 ~ 6.4 mm, the average molar anchorage forward 0.3 - 0.4 mm, the missing cases of unilateral molar molar anchorage forward 1.0 ~ 1.5 mm, the surface shape were improved obviously. Class I , Class IH malocclusion, are to achieve the desired effect. [Conclusion] The self

  9. Study of Mechanical Behavior and Ultimate Carrying Capacity of Suspender Anchorage Zone in Axial Direction of Bridge%顺置式吊杆锚固区受力特性与极限承载力研究

    Institute of Scientific and Technical Information of China (English)

    高小妮; 贺拴海; 齐宏学

    2012-01-01

    To have an understanding of the mechanical behavior and ultimate carrying capacity of suspender anchorage zone set in the axial direction of bridge under the action of suspender forces, a combined cable-stayed and self-anchored suspension system bridge that was being constructed was cited as an example, the software ANSYS was used to set up the spatial shell finite element model, the mechanical behavior of the anchorage zone under the action of the worst load was studied, the ultimate carrying capacity of the anchorage zone was analyzed, respectively u-sing the linear elasticity and nonlinearity analysis methods and the force conditions of the components in the anchorage zone were discussed. The results of the study show that under the action of the worst load, the stress in the steel anchor box and steel anchor beam is less than that in the diaphragm. With the exception that the stress concentration in the welding of the steel anchor beam and diaphragm is notable, the stress distribution in all components is uniform and the deformation of the components in the axial direction of the bridge is great. The results of the different analysis methods for the ultimate carrying capacity also show that when the ultimate carrying capacity of such type of the structure is analyzed, using the shell element model, the material nonlinearity should considered only and in the design of the structure, it is proposed that adequate attention should be paid to the problem of insufficient rigidity of the diaphragm.%为掌握顺桥向设置的吊杆锚固区在吊杆力作用下的受力特性和极限承载力,以某在建斜拉—自锚式悬索组合体系桥为依托工程,利用ANSYS软件建立壳单元空间有限元模型,对锚固区在最不利荷载作用下的受力性能进行研究;并分别采用线弹性及非线性分析方法对吊杆锚固区极限承载力进行分析,讨论构件的受力情况.结果表明:在最不利荷载作用下,钢锚箱及钢锚梁

  10. 斜拉桥索塔锚固区节段足尺模型试验与分析%Test and analysis on full scale segmental model of cable tower anchorage zone in cable stayed bridge

    Institute of Scientific and Technical Information of China (English)

    郭凡; 杨永清; 周厚斌; 刘国军

    2012-01-01

    A FEM model of the cable tower anchorage zone section in certain cable stayed bridge was built to analyze the spatial stress field,and the values obtained by spatial stress analysis and full scale model test were compared.The evaluation of the operating capability and safety of the bridge tower was brought forward.The frictional coefficient values of the U-shaped plastic corrugated pipes and the extension values of tendons were analyzed.Stress distribution and deformation under U-shaped and small radius ring prestressed tendons and cable force were investigated.Some suggestions about constitution and design were given to similar force analysis of cable tower anchorage zone as references.%对某斜拉桥索塔锚固区节段建立有限元计算模型进行空间应力分析,并与足尺模型试验得出的结果相比较,对该桥塔锚固区工作性能及安全性进行评价。测试分析U形塑料波纹管孔道摩阻系数和钢束伸长值,研究了小半径环向U形预应力束与拉索作用下的锚固区应力与变形情况,提出构造及设计上的建议,为设计与施工提供依据,也可为同类斜拉桥索塔锚固区的受力分析提供借鉴。

  11. STABILITY ANALYSIS OF ANCHORAGE FOR SUPER SUSPENSION BRIDGE OVER LONGJIANG RIVER IN YUNNAN PROVINCE%云南龙江特大悬索桥锚碇稳定性分析

    Institute of Scientific and Technical Information of China (English)

    郭松峰; 祁生文; 李正熔; 马健; 柴建峰; 翟文龙

    2011-01-01

    重力式是悬索桥安全的关键结构之一,其支墩的偏移量对悬索桥的稳定性至关重要.拟建的云南龙江特大悬索桥保山岸地层复杂,岩性软弱,地基土力学参数较低.在工程设计中,需预测在施工运行过程中的锚碇支墩偏移量,以合理确定地基是否需要加固处理以及设定加固参数.为此,本文利用FLAC3D按照锚碇基坑开挖、锚碇主体施工、回填及二期构件完成、主缆索连接的施工步骤,依次建立较为精细的数值模型来模拟实际工况.数值分析结果表明:云南龙江特大斜拉桥锚碇保山岸锚碇支墩在回填压重和最大缆力工况下的水平偏移量小于5cm,在允许范围15cm内,锚碇基坑底部沉降量顺桥轴线方向自锚后到锚前逐渐减少,但梯度不大,锚碇略微后倾0.05°,不会发生倾倒翻转,也不需对地基加固.数值计算中发现,岩土参数的取值对计算结果影响有较大影响,为此,作者对变形模量、泊松比、黏聚力、内摩擦角、密度等5个参数进行了敏感性分析.结果表明,在研究区的岩土参数取值范围内,变形模量E敏感度较大,在工程勘察中通过足够的试验合理地确定其值十分重要.%As a style of anchoring the cable of suspension bridge, the gravity anchor is one of the most important elements for the safe of the bridge. The displacement of the anchorage buttress is the key factor for the stability. Thispaper examines the stability of the anchorage for a Super Cable-stayed Bridge planned to be built over Longjiang river in Yunnan Province. It is located in the place with complex stratum condition. The soil strength and modulus parameters are very small at the construction site. Therefore, predicting the displacement of anchorage buttresses under various conditions is very important to design the proposal of foundation treatment and determine treatment parameters reasonably. This paper presents the large-scale numerical models with

  12. A study on the stability of miniscrew on different loading time as orthodontic anchorage%不同时机受力对微种植体支抗稳定性的影响

    Institute of Scientific and Technical Information of China (English)

    朱良燕; 严拥庆; 高益鸣

    2011-01-01

    PURPOSE: To evaluate the stability of the miniscrew on different loading time as orthodontic anchorage. METHODS: 2 healthy adult male Beagle dogs were used in this study. 48 mini-implants were implanted into the maxilla and mandible of the dogs. The miniscrews were divided into 8 different groups, 1 group was loaded Og as control group and the others were loaded 200g forces as experimental groups. 200g forces were loaded on the corresponding mini-implant anchorages immediately after implantation and at the time of lw,2w,3w,4w,5w and 6w after implantation. The dogs were sacrificed at 12w after implantation. Histological progresses of implant -bone interfaces was examined with light microscope.Blue deposition and contact ratio were calculated and analyzed using SPSS13.0 software package. RESULTS: Fibrous and osseous-integration was noted in the interface, there was no significant difference in bone deposition ratio and bone contact ratio. CONCLUSION: Different force loading time does not affect the stability of the mini -implant anchorage.Supported by Natural Science Foundation of Shanghai Jiao Tong University School of Medicine(757).%目的:通过对微种植体-骨组织界面的组织形态学分析,研究不同加载时机对微种植体支抗稳定性的影响.方法:全麻下将48枚微型钛金属种植体植入2只实验Beagle犬双侧上、下颌骨,每只24枚.将48枚种植体分为8组,1组为对照组,负载力值为0g;其余7组为加力组,负载力值为200g.加力组分别在植入术后即刻、第1周、第2周、第3周、第4周、第5周和第6周,用正畸专用镍钛螺旋拉簧对各组微种植钉在相应的时间施加200g的水平拉力.在种植钉植入术后的第6周、第8周和第10周,分别对2只实验犬颈部皮下注射荧光剂四环素、土霉素和钙黄绿素溶液.于植入术后第12周处死实验犬,应用光学显微镜及病理图像分析系统对种植体骨磨片进行纵断面观察,并计算各种植植体-骨

  13. A clinical cephalometric study of mini-implant anchorage for en-masse retraction of eight maxillary anterior teeth%微种植体辅助整体内收上前牙段的头影测量

    Institute of Scientific and Technical Information of China (English)

    张华; 麦志辉; 卢红飞; 艾虹; 文冲

    2011-01-01

    目的:研究微种植体支抗在矫治上颌前突病例中整体内收上前牙段的应用.方法:选择5例上颌前突患者,拔除第二前磨牙,采用直丝弓矫治技术,辅以微种植体支抗同时整体内收前牙段(6个前牙及2个第一前磨牙),通过X线头影测量分析,观察矫治前后上颌骨软硬组织的变化.结果:上颌骨的变化轻微;切牙平均内收(4.6±1.5)mm,压低(0.8±1.1)mm,根尖后移(1.7±1.4)mm,切牙与腭平面的夹角减少(6.8±3.5)度;支抗磨牙水平前移(0.5±0.3)mm,没有出现明显的颌向伸长;上唇突度减少(2.0±0.9)mm,鼻唇角增大(3±2.4)度.结论:微种植体能提供稳定的支抗,同时整体内收上前牙段,最大限度避免支抗的丧失,改善上唇突度.%Aim: To Study the efficiency of mini-implants as intraoral anchorage units for en-masse retraction of the 6 maxillary anterior teeth and 2 first premolars after the second premolars are extracted. Methods: Five patients requiring high anchorage after extraction of the maxillary second premolars were selected for this study. Straight wire appliance and mini-implants were used for en-masse retraction, Horizontal , vertical, and angular positions of the maxillary ? Rst molar and central incisor were evaluated ceph-alometrically before and after orthodontic retraction. Results; The edge of upper incisors were retracted (4. 6 ±1. 5)mm and intruded (0. 8 ±1. L)mm, the root apex moved distally (1. 7 ± 1.4)mm. The maxillary first molars showed mesial movement of (0. 5 ±0. 3)mm. The nasolabial angle increased (3 ±2.4)° and the angle between upper incisor and PP-plane decreased (6. 8 ± 3. 5 ) °. Conclusion: Mini-implants are efficient for intraoral anchorage reinforcement for en-masse retraction and intrusion of maxillary anterior teeth.

  14. 淋水碎裂顶板煤巷锚固试验研究与实践%Anchorage experimental research on a coal roadway with water spraying and broken roof and its application

    Institute of Scientific and Technical Information of China (English)

    何富连; 严红; 杨绿刚; 杨洪增; 李琦

    2011-01-01

    Aiming at the problem of continuous water seepage, spraying and gushing along the borehole of bolt (cable) in rock stratum with rich water, a new waterproofing anchorage agent is introduced; and the corresponding waterproof reaction mechanism and its ratio test on this cartridge are researched. To obtain the strengthen change law of siltstone upon the condition of continuous seepage in the broken roof, the seepage experiment is done respectively in the coal field and laboratory, and the results show: Unsaturated polyester resins of NS-1 and polymer instant rubber powder of XS-1 added with a ratio of 2% are the key points for waterproofing anchorage agent. In the 5 days experimental period, the compressive strength of the experimental silts tones suffering from the continuous effect of the static water experience the change process from the former groups increasing gradually to the two later groups decrease quickly. In the circulation effect between flowing water and air dry, the fracture apertures of siltstones continue increasing in 36-42 h, and the whole strength decreases step by step. On the basis of the experimental observation, the coupling relation between the flowing water in siltstone roof and the supporting structure is thoroughly analyzed. Finally, the results for the bolt and cable anchoring force test with new anchorage agent and supporting application on roadway No. 101101 of Tuanbai coal mine show that cable anchoring force could achieve 208 kN with the draining water content keeping 140 mL/s and applying high pre-tightening force and adopting waterproofing cartridge could solve the supporting problem of continuous seepage in the roof, which ensure the safety and stability of the roadway.%煤巷顶板锚固区域富水岩层支护中出现的沿锚杆(索)钻孔持续渗、淋、涌水难题是工程中亟待解决的问题.采用一种新型锚杆(索)防水锚固剂进行了相关防水性配比试验研究;为了获得煤系碎裂顶板持续渗

  15. 重复荷载作用下钢筋混凝土锚固端黏结性能试验研究%Test study on bonding performance of reinforced concrete anchorage zone under repeated loads

    Institute of Scientific and Technical Information of China (English)

    蒋德稳; 邱洪兴

    2012-01-01

    通过对23个钢筋混凝土试件的静载和重复荷载作用下拔出试验,研究了重复荷载作用下钢筋峰值应变和残余应变、自由端和加载端滑移发展特征,得到了重复荷载作用下黏结应力-滑移滞回曲线变化规律。运用试验测定的钢筋应变,计算了静载和重复荷载作用下锚固端黏结应力分布曲线,总结了重复荷载作用下峰值黏结应力、残余黏结应力变化特征,分析了锚固端黏结应力分布机理。研究结果表明:重复荷载作用后黏结强度并不受重复次数影响;重复荷载作用下,自由端、加载端峰值滑移量和残余滑移量发展均符合疲劳破坏的三阶段特征;当滑移量累积到静载作用下破坏时的峰值滑移量时,发生黏结疲劳破坏;随着重复次数的增加,黏结应力沿锚固长度的分布出现明显的双峰现象,最大黏结应力位于距离加载端和自由端约1/4锚固长度位置处。研究结果可为深入研究混凝土结构疲劳性能提供依据。%23 reinforced concrete Rebar' s peak and residual stress, pull-out specimens were tested under monotonic loading and repeated loading peak slip and residual slip at the loading end and free end were inspected in this test. The bonding stress-slip hysteretic curve was obtained. According to the rebar stress data, the distribution curve in the anchorage was calculated under monotonic loading and repeated loading. Variation characteristics of peak and residual bonding stress under repeated loads were summarized, and bonding stress distribution mechanism was analyzed. Research result shows that bonding strength is not influenced much by repeated loading. The peak slip and residual slip follow the three stage rule of fatigue failure. Bonding fatigue failure occurs when the rebar slippage under repeated loading reaches the maximum slippage under monotonic loading. With the increase of repeating times, the obvious double peak phenomenon was shown in

  16. 3-D Finite Element Study on Rapid Maxillary Expansion Using Implant Anchorage%腭种植体支抗快速扩弓的三维有限元分析

    Institute of Scientific and Technical Information of China (English)

    潘虹海; 黄跃; 杨正; 杨四维

    2011-01-01

    Objective To evaluate the biomechanic changes of craniofacial complex with rapid maxillary expansion using implant anchorage. Methods Rapid maxillary expansion using implant anchorage was simulated with MSC. Marc. Mentat software, restrained at the region around the foramen magnum and the anterior middle point of parietale and foramen. In the area of implant surface, forces of 80 N were applied with rapid maxillary expansion. Different numbers and positions of implant anchorage were chosen. Their influences on the craniofacial complex were analysed. Results The stress distribution and displacement trend of the craniofacial complex under different conditions were approximate. The greatest stress appeared on the areas along the frontonasal suture, zygomaticomaxillary suture, nasomaxillary suture and pterygopalatal suture. Two halves of palatine were separated in a "V" shape. Maximal stress and displacement were found when the implant was located between maxillary canine and first premolar. Conclusion The numbers of implant are not associated with the size of stress and displacement. Greater stress and displacement occur when the implant position is in the front.%目的 研究不同位置和数目腭种植体支抗在快速扩弓时颅面复合体的生物力学变化,为临床应用腭种植体支抗快速扩弓提供理论依据.方法 应用MSC.Marc.mentat 2005 R3软件,模拟上颌快速扩弓,以枕骨大孔边缘及顶骨、枕骨前部中点作为固定,种植体处施加扩弓力.设定扩弓力大小为80 N,模拟不同位置及数目腭种植体支抗快速扩弓,分析不同加载条件对颅面复合体的影响.结果 不同位置及数目腭种植体支抗快速扩弓时颅面复合体的应力分布和位移趋势较为一致,应力较大区域分布在鼻额缝、颧颌缝、鼻上颌缝、翼腭缝,腭中缝呈“V”形打开,种植体位于上颌尖牙和第一前磨牙之间时相应的应力和位移最大.结论 快速扩弓时腭种植体数目

  17. 微型种植体支抗在口腔正畸治疗中的疗效评价%Clinical efficacy of micro-implant anchorage in orthodontics treatment

    Institute of Scientific and Technical Information of China (English)

    安葵; 万惠子; 肖长芬

    2013-01-01

    Objective To investigate the clinical efficacy of micro-implant anchorage in orthodontics treatment.Methods Eighty-three patients undergoing orthodontics treatment were divided into two groups,including the observation group of 42 patients with micro-implant anchorage anti-treatment and control group of 41 patients with traditional orthodontics treatment.The effects and adverse reactions of the two groups were compared.Results 05) o After treatment,the indicators such as the molar shift,the upper central incisors inclination poor and upper central incisors protrusion distance in the observation group were better than those in the control group,and the differences were statistically significant (P < 0.05).The rate of adverse reactions in the observation group was only 7.14 %,significantly lower than in the control group.The difference was statistically significant (P< 0.05).Conclusion The mini-implant in the treatment of orthodontics is better than traditional orthodontics treatment and it is worthy of wider application.%目的 探讨微型种植体支抗在口腔正畸治疗中的疗效.方法 选择本院收治的接受口腔正畸治疗的患者83例,并随机分为观察组(n=42)和对照组(n=41).观察组给予微型种植体支抗治疗,对照组给予传统正畸方法治疗,比较2组患者的治疗效果和不良反应发生情况.结果 治疗后,观察组磨牙移位、上中切牙倾角差及上中切牙凸距差等指标均明显优于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为7.14%,明显低于对照组的36.59%,差异有统计学意义(P<0.05).结论 微型种植体在口腔正畸治疗中具有较佳的支抗作用,明显优于传统的口腔正畸治疗措施,值得临床推广应用.

  18. 片段弓技术结合上颌微螺钉支抗矫治前牙拥挤%Treatment of anterior crowding with maxillary mini-screw anchorage and class Ⅲ elastic traction

    Institute of Scientific and Technical Information of China (English)

    李正明; 刘新强; 黄永谦; 肖芦靖

    2012-01-01

    目的:评价应用片段弓技术结合上颌微螺钉支抗配合Ⅲ类颌间牵引非拔牙矫治单纯前牙拥挤的临床效果.方法:12例单纯前牙拥挤病例,应用片段弓技术,上颌颧下嵴微螺钉支抗配合Ⅲ类牵引拉后牙段向远中,待间隙足够时排齐前牙,对矫治前后的模型及X线头颅侧位片进行测量分析.结果:U1/SN、U1/NA、L1/NB和IMPA均无明显变化,结论:后牙片段弓结合上颌微螺钉支抗可以在保持前牙唇倾度不变甚至轻度内收的情况下排齐拥挤的牙列.%Objective: To evaluate the clinical effects of maxillary mini-screw anchorage and ClassⅢ elastics on non-extraction treatment of anterior crowding. Method: 12 cases of anterior crowding were treated with segmental arch technique and Mini-screws were inserted into the maxillary infrazygomatic crest (IZC) area to pull the posterior segment distally, class Ⅲ traction was used to the distal movement of mandibular posterior teeth. Anterior teeth were aligned until adequate space of front segment was obtained. Model and cephalometric X ray film were examined before and after treatment. Result: The width of upper and lower arch was increased significantly. No significant changes were seen on the angles of Ul / SN, Ul / NA.L1 / NB and IMPA. Conclusion:To those anterior crowding cases.application of segmental arch technique combination with maxillary micro-screw anchorage and Class Ⅲ traction can correct the crowing when the torque of anterior teeth was maintained. The method is suitable for mild to moderate skeletal type I crowding cases.

  19. Acoustic detection technique and numerical on anchorage length test of resin bolt%树脂锚杆锚固长度声波探测技术及数值试验

    Institute of Scientific and Technical Information of China (English)

    刘少伟; 李鑫涛; 樊克松

    2014-01-01

    Aiming at the roof fall problems , due to the anchorage invalidation in coal and rock roadway supported by bolts, in this paper , a resin anchor fixation model of roof bolt in coal and rock roadway was established .By u-sing numerical simulation method , the research on the waveguide characteristics of resin bolt under different ancho-ring types was conducted , and the excitation response characteristic curves of resin bolt with different anchorage length were obtained .The comparison analysis showed that no matter what kinds of anchoring type , the testing re-sults and the practical errors were about 1%-6%.Meanwhile , crushing compensation method could be adopted to decrease detection error .The result showed that the reflected stress wave is a useful and valuable nondestructive tes -ting method .It can realize portable , accurate testing of anchoring length .%针对煤岩巷道锚杆支护锚固失效引起的冒顶问题,建立了煤岩巷道顶板锚杆树脂锚固模型,采用数值模拟的方法对不同锚固方式下树脂锚杆的波导特性进行研究,得到了不同锚固长度与树脂锚杆激振响应特性曲线。通过对比分析,研究得出无论何种锚固方式,检测结果与实际锚固长度的误差大约在1%-6%,同时可采用修正补偿的方法降低检测误差。研究结果得出:采用应力反射波法检测树脂锚杆的锚固长度是一种行之有效的无损检测方法,可实现树脂锚杆锚固长度的便携、准确检测提供技术支持。

  20. 钛合金/不锈钢微植体支抗稳定性的组织学研究%Histological study on the stability of titanium alloy and stainless steel microimplant anchorage

    Institute of Scientific and Technical Information of China (English)

    许志强; 史建陆; 任继业; 林艺翚; 魏小平

    2012-01-01

    Objective: To evaluate the stability of titanium alloy and stainless steel microimplant anchorage after immediate loading. Methods: One titanium alloy microimplant and one stainless steel microimplant were placed in one side of maxilla and the other side of mandible respectively in eight adult male mongrel dogs at random. 1.96 N of constant force was loaded immediately between two micro-implants in maxilla or mandible. Four dogs were sacrificed 4 and 12 weeks respectively after operation. Undercalcified sections longitudinal to the implants were made for histological observation and measurement of the bone contact ratio( BCR) between microimplant and bone interface. Results: All microimplants kept stable. The microimplants had favorable biological consistencies with the fiber and bone around them. The BCR increased with the healing time prolonged. The BCR of titanium alloy group was higher than that of stainless steel group. Conclusion: The healing mode of both microimplants is fibro-osseous integrations when immediate loading is applied. The titanium alloy microimplant is more stable than the stainless steel microimplant as an orthodontic anchorage.%目的:评估钛合金和不锈钢微植体支抗即刻负载的稳定性.方法:选用8只本地成年雄性犬,每只犬任选一侧上颌骨和对侧下颌骨各植入1枚钛合金和不锈钢微植体.同颌2枚微植体间即刻加载1.96 N的力.4周和12周时各随机处死4只实验犬,制作硬组织切片进行组织学研究.结果:所有微植体均没有松动、脱落.微植体与周围组织有良好的生物相容性,种植体周围有纤维组织和骨组织共同包绕.骨结合率随着愈合时间的延长而增高,钛合金微植体骨结合率高于不锈钢微植体.结论:即刻负载下,钛合金和不锈钢微植体支抗的愈合形式都是纤维骨性结合,均可保持稳定,钛合金微植体更为稳定.

  1. 既有无黏结预应力混凝土楼盖改造钢绞线重锚施工技术∗%Construction of Strand Again Anchorage for Concrete Prestressed Floor Reconstruction with Unbonded Tendons

    Institute of Scientific and Technical Information of China (English)

    陈浩; 刘玉辉; 陈维超; 黄伟

    2014-01-01

    以长沙汇源大厦裙楼部分拆除改造工程为对象,从现场试拆除试验、主体结构重锚端部加固梁、楼盖开洞、梳形锚垫板安装、开口式锚具安装、无黏结预应力钢绞线切断、现场监控等技术要点介绍了既有无黏结预应力混凝土楼盖改造钢绞线重锚施工关键技术。采用一种新型开口式钢绞线锚具,确保了拆除过程中的无黏结预应力筋的安全截断及可靠再锚固,使结构中被保留的预应力筋的应力不损失或损失很少,无需二次张拉。监控结果表明:在拆除改造过程中,楼板的应变、位移满足正常使用条件要求,整体结构也没出现倾斜现象,采用该技术确保了整体结构的安全性。工程实践结果表明,该方法取得了良好的效果。%Based on the dismantlement reconstruction engineering of partially podium building of Huiyuan building in Changsha, the technical points of field test on dismantlement, strengthening beam of again anchorage end region,opening in floors,comb anchor plate,open type anchor,blanking, monitoring of the key construction technology of strand again anchorage of concrete floor prestressed transformation with unbonded tendons were introduced. A new open strand anchor is used to ensure the safety blanking and reliable re-anchoring of unbonded tendons in the demolition process,the stress of preservation tendons is no loss or few losses without secondary tensioning. Monitoring results showed that the strain and displacement of floor met the requirements of normal using conditions in dismantlement reconstruction process,the inclined phenomenon of whole structure did not appear, the security of the whole structure was ensured with the technology. Engineering practice showed that this technology obtained a good effect.

  2. The Research of Application of the Looped Prestressed Tendons with Large Tonnage and Small Radius in the Anchorage Zone of Cable-stayed Bridge Tower%大吨位小半径环向预应力在斜拉桥索塔锚固区中的应用研究

    Institute of Scientific and Technical Information of China (English)

    陈建阳; 徐国平; 刘丽; 朱正群

    2001-01-01

    Nowadays the large tonnage and small radius annular prestress system are applied in the anchorage region of large span cable-stayed bridge construction in our country. The application of this system has been a breakthrough of the Design Specification of Highway Bridge and Culvert. In this article, the application of this system applied in the anchorage region of cable-stayed bridge tower has been probed in close connection with the full-scale model test of the anchorage zone of the Wuhan Junshan Changjiang River Bridge.%目前我国大跨径斜拉桥索塔锚固区开始采用大吨位小半径环向预应力体系,该体系突破了现行《公路桥涵设计规范》的规定。结合武汉军山长江公路大桥索塔锚固区足尺模型试验及张拉工艺模型试验对该预应力体系在斜拉桥索塔锚固区中的应用作了深入的探讨。

  3. 施桥船闸下游停泊锚地工程预应力管桩施工工艺%Construction Technology Research on Prestressed Pipe Pile of Shiqiao Shiplock Downstream Anchorage Engineering

    Institute of Scientific and Technical Information of China (English)

    汪萍

    2014-01-01

    Shiqiao Shiplock downstream anchorage engineering soil condition is very poor and the un-derground water level is high.The high strength PHC prestressed pipe pile for reinforcing soft soil foundation is adopted in the project.According to the characteristic condition,the pile sinking tech-nology and the treatment of pile top and bottom connection for prestressed concrete pipe pile are stud-ied.Effective measures to control the position accuracy of pile sinking when pile length up to 6.38m, reduce the surface exposed time and ensure the connection quality of pile top and bottom under the conditions of large excavation in soft soil foundation are performed and good effect has achieved.%针对施桥船闸下游停泊锚地工程现场地质条件,对预应力管桩的沉桩工艺和管桩桩顶与底板的连接处理进行了研究,就送桩长度达6.38 m 如何控制沉桩的位置精度,以及在软土大开挖条件下如何减少地基表层裸露时间,保证桩顶与底板的连接质量,采取了有效措施,取得了良好的效果。

  4. Experimental study on bond and anchorage behavior of glued-in rebar in glulam%胶合木植筋黏结锚固性能试验研究

    Institute of Scientific and Technical Information of China (English)

    凌志彬; 杨会峰; 刘伟庆; 陆伟东

    2013-01-01

    This paper describes an experimental program of 25 glulam specimens with glued-in rebar which aim to investigate the influence of slenderness ratio (λ =la/d) of rebar and glue-line thickness on the pull out load,and bond behavior of glued-in rebar axially loaded parallel to the grain.The failure modes and mechanics of specimens were analyzed.Moreover,in order to obtain the bond stress distribution along the anchorage length of rebar,specimens with strain gauges attached to steel rebar internally were designed.The experimental results show that failure occurs mainly due to pull-out of rebar,shear failure of timber around the glue-line,splitting of timber and yielding of rebar.The pull out load of glued-in rebar increases with the increasing of both the anchorage length and glue-line thickness.The ductile failure of yielding rebar occurs with the slenderness ratio of rebar up to 12.5.Anchorage length and glueline thickness have obvious influence on the bond behavior of glued-in rebar.The distribution of bond stress at rebar/adhesive interface is not uniform,but rather accentuated near both the loading end and the anchorage end,which confirms the theory of Volkersen (1938).The variation of bond stress at rebar/adhesive interface is different from adhesive/timber interface with the increasing of glue-line thickness.With glue-line thickness increased from 2 mm to 6 mm,bond stress at rebar/adhesive interface increases,while decreases at adhesive/timber interface.Appropriate increasing of glue-line thickness is beneficial to the decreasing of peak value of bond stress.%对25个胶合木植筋(带肋钢筋)试件进行对拉试验,研究植筋长细比(λ=la/d)及胶层厚度对胶合木植筋的连接承载力及界面黏结性能的影响,并对试件的破坏形态和破坏机理进行分析.为获得胶层界面黏结应力的分布,设计钢筋内贴片试件进行试验.结果表明,试件的破坏形态主要有钢筋拔出、木材环向剪切、木材劈裂、

  5. Experiment method for the static anchoring capacity for prestressed tendon anchorage assembly%预应力筋——锚具组装件静载试验方法

    Institute of Scientific and Technical Information of China (English)

    张少英

    2012-01-01

    以新钢建设公司承建的新华公司办公楼无粘结预应力钢筋混凝土框架结构工程为例,根据《无粘结预应力混凝土结构技术规程》(JCJ92-2004)、《混凝土结构工程施工及验收规范》(GB50204-2002)的要求,对锚具静载试验进行了记录及探讨。%Taking for example unbonded prestressed reinforced concrete frame construction engineering of office building of Xinhua Company undertaken by Xinyu Steel Building Company,this paper records and discusses the experiment of the static anchoring capacity for prestressed tendon anchorage assembly according to Specifications for Unbonded Prestressed Reinforced Concrete Frame Construction(JCJ92-2004) and Standards for Construction and Check and Acceptance of Reinforced Concrete Structure Engineering(GB50204-2002).

  6. Application value of micro-implant anchorage in orthodontic therapy%微型种植体支抗在口腔正畸治疗中的应用价值

    Institute of Scientific and Technical Information of China (English)

    葛长平

    2016-01-01

    目的:探讨微型种植抗体支抗在口腔正畸治疗中的应用价值。方法选取口腔科门诊2012年4月至2014年7月行正畸治疗患者90例,随机分为两组,每组45例。对照组按照传统方法实施正畸治疗,实验组采用微型种植体开展正畸治疗,对比两组患者的正畸治疗效果及术后并发症的发生情况。结果实验组正畸治疗结束后其上中切牙倾角差、凸距差和磨牙移位情况均明显优于对照组,差异有统计学意义( P<0.05);实验组不良反应的发生率明显低于对照组,差异有统计学意义( P<0.05)。结论微型种植体能够为口腔正畸治疗提供有效的支抗作用,有助于提高正畸治疗的临床效果,安全可靠,建议临床推广。%Objective To investigate the application value of micro-implant anchorage in ortho-dontic therapy.Methods From April 2012 to July 2014, 90 patients with orthodontic treatment were se-lected, and they were randomly divided into two groups , with 45 cases in each group .The control group was given traditional orthodontic treatment methods , the experiment group were conducted with micro-im-plant orthodontic treatment , the effect of orthodontic , and postoperative complications of the two groups were compared.Results After the end of the orthodontic treatment , the inclination poor, poor and teeth protruding from the shifting of the patients in experiment group were significantly better than those in con-trol group , the differences were significant ( P<0.05 );The incidence of adverse reactions in patients of experiment group was significantly lower than that of control group , the difference was significant ( P<0.05 ) .Conclusions Mini implants can provide effective treatment for orthodontic anchorage , help to improve the clinical effectiveness of orthodontic treatment , and it is safe and reliable , so it is recommen-ded to further promote in clinical practice .

  7. 个体化弓丝和横腭弓联合强化支抗的临床应用%The effect of anchorage enforcement of customized archwire integrated with TPA-A preliminary clinical study

    Institute of Scientific and Technical Information of China (English)

    陈荣敬; 胡铮; 沈刚

    2009-01-01

    Objective This study was designed to examine the effect of the custom-bent archwire in enforcing molar anchorage during canine and /or incisal retraction.Methods 24 female adult patients diagnosed with Class Ⅰ with severe crowding or Class Ⅰwith moderate crowding and proclined upper incisors,were included into this study.The age of the patients ranged from 18 years 8 months to 25 years 5 months.As required by treatment plan, hte patients were extracted uppe &lower premolars to relieve crowding and retract frontal teeth. The upper starting archwire of 0.018ss was custom-bent with its first order bends fitting to the irregularities of the upper dentition,so that it was engaged into the brackets passively.The transpalatal Arch(TPA) was also placed transversely connecting bilateral molars.Canine disalzation was implemented firstly using ligature wire lace-back then active power-chain elastics.Study models and cephalograms were taken before and after orthodontic treatment and the parameters,namely,Ptm-6,S0-6AP and 6-PP were measured to indic ate the displacement of the molars.Results (1)Althouth the increase in Ptm-6 and So-6AP was significant(P0.05),indicating a good control of the molars even in vertical dimension.Conclusions A combined use of custom-bent archwire with TPA enhances molar anchorage.%目的 评价安氏Ⅰ类错(牙合)矫正治疗中个体化弓丝和横腭弓联合应用的支抗控制效果.方法 选择18岁8个月至25岁6个月安氏Ⅰ类错(牙合)女性患者24例,分析个体化弓丝和横腭弓联合应用加强支抗治疗前后的X线头影测量值的变化.结果 Ptm-6与So-6AP虽有增大(P<0.05),但支抗磨牙的前移量不到拔牙间隙的1/5;6-PP、MP-FH及ANS-Me治疗前后均无显著性改变(P>0.05),支抗磨牙在垂直方向上也得到了有效的控制;水平方向上无支抗磨牙的舌向倾斜及近中舌向扭转.结论 个体化弓丝和横腭弓联合应用能有效地稳定支抗磨牙.

  8. An animal experimental study of the loading time on anchorage implant stability%微型支抗种植钉加载时机的动物实验研究

    Institute of Scientific and Technical Information of China (English)

    武红梅; 冯云霞; 李罡

    2014-01-01

    目的:建立支抗种植钉的动物模型,分析不同愈合期加载对种植钉稳定性的影响。方法于绵羊牙槽骨上植入微型支抗种植钉,建立颌骨-支抗种植钉的动物模型,随机分为4组(不加力为A组,即刻加力为B组,植入2周加力为C组,植入4周加力为D组),截取带有种植钉的上、下颌骨组织标本;上颌骨块制作不脱钙的骨磨片,光镜下观察种植钉与骨组织界面的愈合情况,下颌骨块用材料性能试验机检测种植钉与骨组织松脱瞬间的最大剪切力值,并进行统计分析。结果1)4组种植钉的剪切力值总体上有差别,A、B组的剪切力低于C、D组。2)骨纵磨片显示:种植钉与周围组织界面的结合方式在种植钉的压力侧和张力侧无明显区别;横断磨片显示:4组界面既有纤维性结合,又有骨性结合,A、D组界面以骨性结合为主,B、C组界面以纤维性结合为主,C组种植钉周围可见新生的骨组织潜行生长。结论加载时机对支抗种植钉的稳定性有一定的影响。%Objective This study aimed to evaluate the influence of loading in different healing periods on implant stabi-lity and to establish an animal model of anchorage implant screws. Methods Anchorage implant screws were implanted in sheep alveolar bone to establish the implant screw animal model. The animals were randomly divided into four groups: group A, sheep without loading; group B, sheep loaded immediately after implant; group C, sheep loaded after two weeks; and group D, sheep loaded after four weeks. The maxillary and mandibular tissue specimens with implants were dissected. The maxillary tissue specimens were used to make undecalcified bone grinding slices, and the healing mode of the implant-bone interface was observed by light microscope. The maximum shear strength of loose mandibular specimens was measured by a material testing machine. The differences in group data were

  9. Experimental Research on Stress Behavior of Stud Shear Connector in Tower Anchorage Area of Cable-stayed Bridge%斜拉桥锚固区栓钉剪力键力学特性研究

    Institute of Scientific and Technical Information of China (English)

    吴秀发; 张小亭

    2014-01-01

    针对栓钉剪力键用于斜拉桥索塔锚固区连接部位时的应力应变特性,以中部横梁均匀加载为思路,建立局部试验模型,以栓钉剪力键的极限承载力为依据,设计加载方案,通过试验获取栓钉的应变随荷载变化的基本特征,并分析了破坏机理。结果表明:中部加载使模型两侧剪力键受力均匀,设计更为合理;栓钉剪力键的剪应力以加载梁为中心向两侧逐渐降低;高度方向,第7排栓钉受力最大,长度方向,单钉根部受到的剪力最大,应作为控制截面;破坏时,栓钉弯曲变形,根部发生45°剪切破坏,混凝土局部产生裂缝或压碎破坏。%This article mainly studied the stud shear connector for anchorage zone of pylon cable-stayed bridge connecting parts when subject to stress-strain characteristics.Taking central uniform load for ideas established local test model.Loading program was designed which based on the ultimate bearing ca-pacity of stud shear connector.It has acquired the basic characteristics of stud strain with load variation and analyzed the failure mechanism.The results showed that:The model adopts central loaded design is more reasonable because it makes shear connector force uniform on both sides of the model.The shear stress of stud shear connector decreased gradually from the center to both ends of the load beam.In the height direction,the 7th rows of pegs subject the maximum shear stress.In the longitudinal direction,sin-gle nail roots subject the maximum shear stress.It should be used as the control section.When the stud destruction,the stud bending deformation occurs,peg roots shear failure in direction of 45 °,the partial concrete will produce cracks or be crushed.

  10. Comparative study of clinic effects of segmental archs and mini-implants for orthodontic anchorage on orthodontic canine distalization%片段弓与微种植体支抗拉尖牙向远中的临床应用对比研究

    Institute of Scientific and Technical Information of China (English)

    徐晓静; 沈云娟; 秦燕军

    2012-01-01

    Objective To compare the clinic effects of segmental archs and mini-implants for orthodontic anchorage on orthodontic canine distalization. Methods 60 cases of dental crowding, whose four first premolars were extracted and canine distalization was needed according to the treatment protocol, were randomly divided into 2 groups. Mini-implants were used in the cases in experimental group as orthodontic anchorage to move canine distally, and segmental archs were used in the control cases. The distances of canine dis-talizalion and the angles of anchorage molar inclination in 60 cases were measured and compared. Results The mean velocity of canine distalizalion in the experimental group was (1.428 ±0.072) mm/month,which was faster than(l. 137 ±0.081)mm/month in the control group. The degree of molar inclination (1.27 ±0.18) in the experimental group was less than that in the control group (1.91 ±0.13). Statistic analysis showed that there were significant differences. Conclusions The mini-implants for orthodontic anchorage can move the canine faster and control the anchorage molar better than the segmental arch.%目的 比较片段弓技术和微种植体支抗在拉尖牙向远中的临床应用效果.方法 60例牙列拥挤,双侧对称拔除第一前磨牙且需将尖牙拉向远中的患者,随机分为2组,试验组尖牙远移时应用微种植体作为支抗,对照组则使用片段弓技术远移尖牙,测量尖牙向远中移动的距离以及磨牙近中倾斜的程度.结果 试验组尖牙移动的速率为(1.428±0.072)mm/月,快于对照组(1.137±0.081)mm/月;试验组磨牙近中倾斜程度为(1.27±0.18)°,小于对照组(1.91±0.13)°.经统计学检验差异均有显著性(P<0.05).结论 使用微种植体支抗拉尖牙向远中在牙齿移动速率以及控制磨牙近中倾斜等方面优于片段弓技术.

  11. Stress analysis of mutated Class Ⅱ intermaxillary traction system to mandibular anchorage teeth%改良型Ⅱ类颌间牵引致下颌支抗牙受力变化分析

    Institute of Scientific and Technical Information of China (English)

    程自力; 刘长庚; 莫业跃; 赵殿才; 尹高权; 黄小芳

    2012-01-01

    Objective To explore the stress and movement feature of anchorage molars result from mutated Class II intermaxillary traction, and to analyse the related influencing factors. Methods Refers to the Model Typodont's principle and the simplified appliances to measure the experimental teeth mechanical force and movement were designed and made. According to the differences of the loading points, strength and angle of the force, the objective teeth were separated into four experimental groups, and each one had three samples. Group I : loading points were at the level of mesiolin-gual cusp; the upper loading points were at the level of maxillary canine teeth; the force was 30 degree and 150 gram. Group II ; loading points were at the level of distolingual cusp, upper loading points were at the level of maxillary canine teeth; the force was 30 degree and 150 gram. Group III : loading points were at the level of mesiolingual cusp, upper loading points were at the level of maxillary canine teeth; the force was 30 degree and 100 gram. Group IV: loading points were at the level of mesiolingual cusp, upper loading points were at the level of maxillary prcmolar; the force was 60 degree and 100 gram. The mesiobuccal cusp, mesiolingular cusp, disdal cusp and distolingular cusp' s highest points of the experimental teeth were chosen as fixed index points, and the benchmark lines of the measure equipment as the reference point lines, and then the distances between index points and benchmark lines before and after the experiments were measured. Results Under the traction force, all the testing teeth showed clear mesial movement (the value of dot a and b, which represents the mesial displacement, was 0. 50 mm and 3.33 mm respectively) and buccal movement (the value of dot c and d, which represents the buccal displacement, was 2.67 mm and 6. 17 mm respectively) , and were oc-clusally elongated {the value of dot g and h, which represents the vertical displacement, was 0. 22 mm and 4. 00

  12. 76 FR 52599 - Anchorage Regulations; Wells, ME

    Science.gov (United States)

    2011-08-23

    ... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting. But, you may... Wells, Maine. All coordinates referenced use datum: NAD 83. Dated: Aug. 9, 2011. Daniel A. Neptun,...

  13. 77 FR 6010 - Anchorage Regulations; Newport, RI

    Science.gov (United States)

    2012-02-07

    ...; Newport, RI'' in the Federal Register (76 FR 59596). We received no comments on the proposed rule. Basis.... * * * * * Dated: January 20, 2012. Daniel A. Neptun, Rear Admiral, U.S. Coast Guard, Commander, First Coast...

  14. 76 FR 59596 - Anchorage Regulations; Newport, RI

    Science.gov (United States)

    2011-09-27

    ... FR 3316). Public Meeting We do not now plan to hold a public meeting. But, you may submit a request...) of this section. * * * * * ] Dated: September 13, 2011. Daniel A. Neptun, Rear Admiral, U.S....

  15. Explaining the democratic anchorage of governance networks

    DEFF Research Database (Denmark)

    Skelcher, Chris; Klijn, Erik-Hans; Kübler, Daniel;

    2011-01-01

    on the relationship between network governance and representative institutions in four European countries: the United Kingdom, Switzerland, the Netherlands, and Denmark. The article shows that the distinction between majoritarian and consensus democracy as well as the varying strength of voluntary associations...... are important contextual factors that help explain cross-national differences in the relationship between governance networks and representative institutions. We conclude that a context of weak associationalism in majoritarian democracies facilitates the instrumentalization of networks by government actors...

  16. Annual game report, Anchorage district, 1955

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Facilities, personnel, equipment, funds, communications, patrol activities, record of travel, cooperative activities, and game law violations.

  17. Measuring the democratic anchorage of governance networks

    DEFF Research Database (Denmark)

    Fotel, Trine; Sørensen, Eva; Torfing, Jacob

    . This debate is found wanting in two respects. First of all, there has been far too little discussion about what democracy means in relation to pluricentric governance networks. Second, the current debate builds on the assumption that it is possible to give a clear-cut answer to the question of the democratic...

  18. Factors influencing the stability of miniscrew implants as orthodontic anchorage%影响微螺钉支抗种植体稳定性的相关因素

    Institute of Scientific and Technical Information of China (English)

    季清皎; 刘忠汉

    2013-01-01

    目的:探讨影响微螺钉种植体作为支抗植入后的稳定性相关因素。方法:回顾性分析在44名患者中植入的100枚微螺钉种植体,临床因素包括患者的性别、年龄,负载的时间,微螺钉的大小,种植的部位。结果:种植成功率为83.0%。即刻负载种植成功率为94.4%明显高于延期负载种植成功率的76.6%,有统计学差异(P<0.05)。直径1.6mm螺钉种植成功率为93.0%,直径2.0mm螺钉种植成功率为75.4%,两者比较P<0.05。上颌种植成功率为91.7%,下颌种植成功率为75.0%,两者比较P<0.05。结论:微螺钉支抗种植体稳定性跟种植部位、种植螺钉的大小以及种植后负载的时间有关,而跟性别、年龄以及牙弓内左右侧、前部后部无关。%Objective: To investigate the factors influencing the stability of miniscrew implants as orthodontic anchorage. Methods: In this retrospective study, the records of 100 miniscrews inserted in 44 patients were evaluated. The clinical variables evaluated included the gender and age of patients, the time of load application, the size of miniscrews, the screw location in the bone. Result:The overall success rate in this study was 83.0%. The success rate of immediate loading was 94.4%, significantly higher than the success rate of delayed loading which was 76.6%(P<0.05). The success rate of 1.6mm-diameter miniscrew implants was 93.0%and the success rate of 2.0mm-diameter miniscrew implants was 75.4%, respectively(P<0.05). In case of miniscrew implants in maxilla, the rate was 91.7%, while for miniscrew implants in mandible, it was 75.0%, with the difference of P<0.05. Conclusion: The stability of mini-screw implants is related to the location in the bone, the sizes of miniscrews and the time of load appli-cation, rather than the gender and age of patients; the left and right side, the anterior and posterior in dental arch were not affected the stability.

  19. 武汉鹦鹉洲长江大桥北锚碇新型沉井基础设计%Design of New Type Caisson Foundation for North Anchorage of Yingwuzhou Changjiang River Bridge in Wuhan

    Institute of Scientific and Technical Information of China (English)

    李明华; 杨灿文

    2011-01-01

    The main bridge of Yingwuzhou Changjiang River Bridge in Wuhan is a three-tower and four-span suspension bridge. After comparison of different design proposals, it was determined that a new type caisson structure of circular cross section and with multiple round wells would be used for the north anchorage foundation of the bridge. In the big size well in the center of the caisson, the crisscross diaphragm was set and along the periphery within the caisson, a number of small size wells were uniformly set. The caisson is 43 m high and has totally 8 lifts, of which the first lift is a steel shell concrete caisson and the rest parts of the caisson from the second to the eighth lifts are all of reinforced concrete caissons. In the construction of the caisson, the caisson was sunk down by no dewatering and the air curtain was provided in the caisson wall to reduce sinking difficulty and construction risk. The software FLAC3D was used to conduct numerical simulation and analysis of the construction process of the sinking and to evaluate the construction safety, the environmental effect caused by the construction and the deformation of the foundation to be applied with load after the bridge was put into operation. The results of the a-nalysis show that in the process of sinking the caisson in lifts, the caisson structure and ground deformation can meet the relevant requirements in the codes and the adverse influence of the construction on the ambient buildings and the river dyke can be effectively avoided.%武汉鹦鹉洲长江大桥主桥为三塔四跨悬索桥.该桥北锚碇基础经多方案比选采用多圆孔环形截面新型沉井结构.沉井中间大圆孔内设置十字形隔墙,圆环内沿圆周均布有小直径井孔.沉井总高43 m,共分8节,第1节为钢壳混凝土沉井,第2~8节均为钢筋混凝土沉井.北锚碇施工中采用不排水下沉、井壁增加空气幕等措施减小施工难度及风险.采用软件FLAC3D对沉井施工过程进

  20. 异型钢箱混凝土索塔锚固区空间力学行为研究%Spatial Mechanical Behavior Research of Cable-pylon Anchorage Zone of Steel Box Concrete Tower

    Institute of Scientific and Technical Information of China (English)

    党栋; 贺拴海; 赵煜; 李世安

    2012-01-01

    In order to grasp the force performance and stress distribution of shaped pylon steel anchor box under the action of the cable tension, with a main span of 555 m length of three towers cable-stayed and self-anchored suspension combined system bridge as the engineering background, through the ANSYS APDL command stream parametric programming, the different finite element models of pylon steel anchor box is established by the spatial solid element and shell element, the mechanical properties of cable-pylon anchorage zone were studied under the most unfavorable load combination, considering the stress state and distribution characteristics of steel anchor box under different orthodontic force. The results showed that;under the most unfavorable combination of loads, the stress was concentrated at the position of the anchor plate and pressure plate using the initial strain mode; the calculation results of solid element and shell element were consistent by uniform loading mode, which could reflect the real stress state of steel anchor box, but the shell element corner contact area prone to stress calculation distortion. The results provide the basis for the design and have some design reference value for the design of the same type bridge.%为了掌握异型索塔钢锚箱在索力作用下的受力性能和应力分布,以某主跨555 m 长的三塔斜拉-自锚式悬索组合体系桥为工程背景,通过 ANSYS 中 APDL 命令流参数化编程,分别采用空间实体单元与壳单元建立了不同的索塔钢锚箱有限元模型,对索塔锚固区在最不利荷载组合作用下的受力性能进行了研究,并考虑了在不同加力方式下钢锚箱应力状态和分布特点.结果表明:在最不利荷载组合作用下,采用初应变加力方式,在锚垫板与承压板位置处应力较集中;采用均布力加载方式下,实体单元与壳单元计算结果较为吻合,能真实反映钢锚箱受力状态,但壳单元角点接触部位易出现应

  1. Clinical study of traction preservation of maxillary anterior teeth residual root with microscrew anchorage%种植钉牵引保存上颌前牙残根的临床研究

    Institute of Scientific and Technical Information of China (English)

    温兴涛; 任柏林; 包丽娜; 李东健

    2015-01-01

    目的:通过种植钉辅助正畸加力牵引上前牙龈下残根,评价其使用效果。方法选择上前牙冠折病例18例,前牙10例,前磨牙8例。在需要牵引的牙齿附近植入2颗彼此平行的微种植钉,用树脂粘接托槽,将片段弓固定在托槽上,牵引龈下残根。结果所有患牙断端均达到龈缘上1mm以上,向移动距离为2.8~4.3mm。15例合格,3例修复体松动达Ⅱ度,判定为不合格。结论利用正畸方法牵引龈下牙根,再行桩冠修复,可有效地解决前牙美观的问题,这种方法不需要以邻牙或对牙作为支抗,能有效避免支抗牙移位或支抗丧失的不良反应。%Objective   To evaluate the effect of orthodontic extrusion with microscrew anchorage in the repair of reexposed subgingival residual root. Methods   A total of 18 cases of anterior teeth with crown fracture, 10 cases of anterior teeth, and 8 cases of premolar were chosen. Two parallel microimplants were implanted near the traction dental implant, with resin-bonded brackets. Segmental arch is fixed on the bracket and traction of subgingival residual root. Results   The broken end of all teeth reached a gingival margin of 1 mm. The distance of the occlusion to the mobile was 2.8 mm to 4.3 mm. Among 18 patients, 15 cases were qualified, and 3 cases of prosthesis were unqualified. Conclusion  Orthodontic traction with microscrew anchorage has good effect on the repair of under-the-gum residual root. The greatest advantage of this method is that it does not need to use adjacent teeth or antagonistic teeth as anchorage, thus effectively avoiding the

  2. 爆炸荷载下不同锚固参数围岩的加速度响应分析%Acceleration response analysis of surrounding rock with different anchorage parameters subjected to explosive loads

    Institute of Scientific and Technical Information of China (English)

    杨自友; 杨本水; 顾金才; 李永池; 高光发

    2011-01-01

    If acceleration of rock mass is too large, the surrounding rock of underground cavern is not stable.By analyzing time-history curves of acceleration obtained by model test, the acceleration response characteristics of surrounding rock with different anchorage parameters in underground cavern subjected to explosive loads are studied.The forms and peak values of the time-history curves of acceleration of underground cavern's crown, floor and two sides are explained respectively.Because of the different reinforcing modes, the distinctions of the acceleration response of surrounding rock of underground cavern are compared emphatically.The results indicate that the time-history curves of the vertical acceleration of crown and the horizontal acceleration of floor right side are smooth enough; but the vibration of the time-history curves of the vertical acceleration of floor and the left side are larger than the others.The acceleration of the crown is the largest than the other positions.For the cavern of the smallest spacing of rock bolts in four underground caverns, the acceleration of its crown and two sides is smaller than the other caverns; but the acceleration of its floor is larger slightly than the others'.By means of comparing and analyzing above, reducing the spacing of the rock bolts can enhance the stabilization of underground cavern.%地下洞室岩体加速度过大易造成围岩的不稳定,通过由模型试验得到的加速度-时程曲线分析,研究了爆炸荷载作用下不同锚固参数洞室围岩的加速度响应特征.分别阐述了洞室拱顶、底板、两帮加速度时程曲线的形态及其峰值大小,重点比较了洞室围岩因锚杆加固方式的不同对爆炸产生加速度响应的差异,结果表明,拱顶垂直和右帮水平加速度-时程曲线较光滑,而底板和左帮垂直加速度-时程曲线存在较大震动;洞室拱顶加速度峰值最大;4个洞室中锚杆间距最小的洞室,其拱项、两帮加速度

  3. CLINICAL EFFECTS OF DEPRESSING EDENTULOUS AREA WITH MICRO -SCREW IM-PLANT ANCHORAGE COMBINED WITH SEGMENTAL ARCH TECHINIQUE ON POSTERI-OR TEETH IN ELONGATED JAW%应用微螺钉种植体支抗联合片段弓技术压低缺牙区对颌伸长后牙的临床探讨

    Institute of Scientific and Technical Information of China (English)

    张金望

    2015-01-01

    Objective To study the application of micro -screw implant anchorage combined with segmental arch technique on posterior teeth in elongated jaw to depress edentulous area.Methods 29 adult patients with 31 posterior teeth were depressed with micro -screw implant as skeletal anchorage combined with segmental arch tech-nique in order to help restoration.Results 31 posterior teeth in the experimental group were successfully depressed to the occlusal plane with micro -screw implant anchorage combined with segmental arch technique in order to create restoration space in edentulous area with an average course of treatment of 10 months.29 posterior teeth in the control group were grinded and given root canal therapy to create restoration space in edentulous area.Conclusion The ap-plication of micro -screw implant anchorage combined with segmental arch technique on posterior teeth in elongated jaw to depress edentulous area is an effective straightening method, whereas grinding is the last resort in creating res-toration space in edentulous area.Because patients in primary hospitals have relatively low oral health awareness, some hope for faster and easier solutions and find it difficult to accept traumatic micro -screw implant.%目的:研究微螺钉种植体支抗联合片段弓技术在压低缺牙区对颌过长后牙中的应用。方法使用微螺钉种植体作为骨性支抗联合片段弓技术对29例成人患者共31颗后牙进行压低,以利于修复。结果实验组微螺钉种植体联合片段弓技术31颗后牙均成功压低至咬合平面,为对颌缺牙区开辟修复空间,平均疗程10个月。对照组29颗后牙采用调磨对颌牙后根管治疗的方法为缺失牙开辟空间。讨论使用微螺钉种植体支抗联合片段弓技术压低缺牙区对颌伸长后牙,为缺牙区开辟空间,是一种有效的矫治方法。而调磨对颌牙为缺失牙开辟空间的方法在基层实为不得已而为之。因为基层医院

  4. 采用铸造垫板的预应力混凝土锚固区传力性能试验%Experimental study of the load transfer behavior of post-tensioned concrete anchorage zone with cast bearing plate

    Institute of Scientific and Technical Information of China (English)

    赵勇; 李东彬; 程志军; 朱万旭; 周建民

    2011-01-01

    To revise the professional standard "Technical Specification for Application of Anchorage,Gripand Coupler for Prestressing Tendons" , thirty-eight local compression specimens were tested under monotonic or cyclic loading. The load transfer behavior in the anchorage zone of post-tensioned concrete members with domestic cast bearing plates, including the failure pattern, cracking load, ultimate capacity, and crack width, were investigated. The influence of the relevant parameters was also studied. The results indicated significant deviations in most cases between the predicted values of local compressive capacity, according to the design code GB50010-2002, and the test values. It is thus necessary to adopt the requirements of load transfer tests for post-tensioned concrete anchorage zones into the related national or professional standards. The ultimate capacities of most specimens under monotonic loading were larger than the nominal ultimate tensile force of prestressed tendons ( Fptk ) , but very few could reach 1. 2Fptk. The ultimate capacities of monotonic loading tests were approximately 1. 1 times of the corresponding results of cyclic loading tests. The ultimate capacity could be enhanced by assembling multiple bearing surfaces, enlarging the diameter of spiral reinforcement, and increasing the concrete strength and the cross-section size of anchorage zone. The cracking loads could be increased and the bursting crack widths could be substantially reduced by using skin reinforcement.%结合行业标准的修订,完成38个局部承压试件的单调加载或循环加载试验,研究采用国产铸造垫板的预应力混凝土锚固区传力性能,包括破坏模式、开裂荷载、极限承载力和裂缝宽度等,并进行相关影响参数分析.试验结果表明,采用(GB 50010-2002)局部受压承载力公式估算整体铸造垫板锚固区的极限承载力与试验值会有较大偏差,有必要在国内相关标准中纳入后张预应力混凝土

  5. 76 FR 78185 - Anchorage Regulations: Subpart A-Special Anchorage Regulations, Newport Bay Harbor, CA

    Science.gov (United States)

    2011-12-16

    ... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting. But, you may... highlighted in blue. In the ``Document Type'' drop down menu select ``Proposed Rule'' and insert ``USCG-2010..., design, or operation; test methods; sampling procedures; and related management systems practices)...

  6. CLINICAL APPLICATION OF MICRO -SCREW IMPLANT ANCHORAGE IN TREATMENT OF ANGLE'S CLASS II DIVISION 1 MALOCCLUSION WITH DEEP OVERBURDEN JAWS%微螺钉种植体支抗在 Angle 氏 II 类1分类深覆颌深覆盖牙颌畸形治疗中的临床应用

    Institute of Scientific and Technical Information of China (English)

    张金望

    2015-01-01

    目的:应用微螺钉种植体支抗植入Angle氏II类1分类深覆颌深覆盖牙颌畸形患者上颌牙列,加强支抗,比较其上颌切牙与第一磨牙的位置变化,探讨自攻型微螺钉种植支抗比传统支抗是否具有优越性。方法选择Angle氏II类1分类深覆颌深覆盖患者68例,随机分为研究组和对照组。研究组使用自攻型微型种植钉作为支抗体;对照组使用Nance弓、横腭杆或口外弓联合作为强支抗。比较两组总的治疗时间,及治疗前后X线头影测量的线距和U1/SN的角度差值。结果①微型种植钉保持稳定而无松动,种植体周围软组织健康,无肿胀感染,患者无明显不适。②研究组平均疗程20个月,对照组平均疗程26个月。③研究组患者在软组织侧貌得到显著的改善,上下唇相对于审美平面分别内收4.26 mm和4.54 mm。 U1/SN角减小了10.2°;对照组上下唇相对审美平面分别内收2.88 mm和3.01 mm。两组之间的差异有统计学意义。研究组上颌第一磨牙矫治前后在前后向和垂直向未发生显著性移动( p>0.05),切牙在前后向发生显著性移动,组间的差异有统计学意义( p<0.01)。结论相比传统支抗技术,微螺钉种植支抗能够更好地控制牙齿移动,缩短整个治疗时间。%Objective To assess theapplication values of self -tapping micro-screw implant anchorage in treatment of Angle's class II division 1 malocclusion with deep overburden jaws , compared with the traditional anchor-age.Micro-screw implantswere inserted in maxillary teeth of patients with Angle's class II division 1 malocclusion with deep overburden jaws tostrengthen anchorage .Changesin position of the maxillary incisor and the first molar were compared.Methods 68 cases of Angle's class II division 1 malocclusion with deep overburden jaws were selected and randomly divided into the research group and the control group .The

  7. Effect of Low Bone Metabolic Rate on the Stability of Immediate Loading Micro-Implant Anchorage in Rats%低骨代谢率对微型种植支抗即刻负载稳定性的影响

    Institute of Scientific and Technical Information of China (English)

    张彬; 李冠娥; 李金源; 廖囡囡; 刘蓉艳

    2011-01-01

    目的:研究在低骨代谢率情况下,即刻负载微型种植体支抗的可行性及稳定性.方法:健康Wistar雌性大鼠20只,随机分成2组,每组10只.低骨代谢组(甲减组)给予0.1%丙基硫氧嘧啶;对照组给予蒸馏水,2组均按10μL/g体质量每天灌胃.28 d后植入微型种植体并加力0.98 N,分别于加力后第16、17、26、27天进行标记,加力后30d处死动物.通过X线片测量种植体骨内移动间距;荧光显微镜、光镜下观察含种植钉超硬组织切片并计算骨矿化沉积率、骨结合率.结果:造模后甲减组血清三碘甲状腺原氨酸(T3)、甲状腺素(T4)水平低于对照组,而促甲状腺激素(TSH)则显著高于对照组,甲减组种植体骨内移动间距、骨矿化沉积率及骨结合率均低于对照组.结论:低骨代谢率对微型种植体稳定性有显著影响,低骨代谢情况下微型种植体即刻负载是可行的.%Objective : To investigate the effect of the low bone metabolic rate on the feasibility and stability of immediate loading micro-implant anchorage. Methods : Twenty healthy female Wistar rats were randomly divided into two groups,namely hypothyroid group and control group. There were 10 rats in each group. Rats of hypothyroid group were given intragastrically 10 μL/g, 0.1% propylthiouracil, and rats in control group were given intragastrically distilled water in the same manner for 28 days. Then micro-screws were implanted and 0.98 N force was loaded to all rats. After loaded 16 d, 17 d, 26 d and 27 d, rats were marked by tetracycline and calcein. All rats were killed after loaded 30 days. The mobile space was measured by X-ray. Super-hard nail tissue sections containing plant were observed under fluorescence microscopy and light microscopy. The bone mineral deposition rate and bone contact ratio were calculated. Results: The serum levels of T3 and T4 were lower in hypothyroid group than those of control group, but the level of TSH was significantly

  8. Core binding factor alpha 1 expression in condylar cartilage under different microscrew anchorage orthodontic forces%微支抗种植体及不同矫治力作用下髁突软骨中核心结合因子a1的表达

    Institute of Scientific and Technical Information of China (English)

    赵刚; 邵鑫; 李德超; 张庆宇; 王丹

    2011-01-01

    BACKGROUND: Recently, microscrew anchorage implant has been widely used in the orthodontics due to its simple operation, little trauma and strong anchorage, but it is rarely used in type Ⅱ intermaxillary extraction. OBJECTIVE: To establish the animal experiment model of orthodontic microimplant, to investigate the effects of orthodontic forces on the expression of core binding factor a1 (Cbfa1) in condylar cartilage and on condylar process modification. METHODS: Thirty 8-week-old healthy New Zealand rabbits were randomly divided into experimental group (n=24) and control group (n=6). According to different forces, the experimental group was randomly subdivided into four groups: 100 g, 200 g, 300 g, and 400 g. Rabbits from the experimental group were performed type Ⅱ intermaxillary extraction taking microscrew implants as anchorages. At 4 weeks after surgery, Cbfa1 expression in the condylar cartilage was detected. RESULTS AND CONCLUSION: Different orthodontic forces resulted in different Cbfa1 expression in the condylar cartilage. When orthodontic force was 100 g and 200 g, Cbfa1 expression was significantly higher compared with the control group and orthodontic force of 200 g lead to highest Cbfa1 expression. When the orthodontic force was 300 g, there was no significant difference between the experimental and control groups (P > 0.05). When orthodontic force was 400 g, Cbfa1 expression was significantly greater in the experimental group than in the control group (P < 0.05). Orthodontic force can influence the expression of Cbfa1 in the condylar cartilage, suggesting that appropriate orthodontic forces have good effects on remodeling condylar cartilage.%背景:近年来微支抗种植体以其操作简单、创伤小、支抗强等优点被正畸医生广泛应用于口腔正畸临床,但鲜见用于Ⅱ类颌间的牵引.目的:以微种植体为支抗,探讨不同矫治力促兔下颌前导后髁突软骨中核心结合因子a1 蛋白的表达及

  9. 微型种植体支抗压低犬切牙移动过程中牙周牙根骨性组织的变化%Histological changes of tooth root and periodontal tissue during mini-implant anchorage for incisor intrusion in dogs

    Institute of Scientific and Technical Information of China (English)

    葛振林; 卢嘉静; 祁涛; 田佳灵; 杨彩霞

    2011-01-01

    BACKGROUND: Tooth intrusion easily leads to root resorption. Previous studies regarding orthodontic treatment-caused tooth root resorption or retrospective clinical studies based on X-ray films have great errors in outcome evaluation because of intrusion force which cannot be precisely controlled. OBJECTIVE: This study established dog models of mini-implant anchorage for incisor intrusion to observe the histological changes of tooth root and periodontal tissue and to evaluate the feasibility and safety of mini-implant anchorage for incisor intrusion. METHODS: Nine dogs were assigned to one control group (n = 1) and four experimental groups per time to sacrifice (1, 2, 4 and 12 weeks; n = 2 dogs for each experimental group). No force was added to the control group. In the experimental groups, mini-implant as an anchorage was placed in the buccal alveoli between maxillary second and third incisors on each side. A traction force of 100 g was imposed to each side to intrude the maxillary first and second incisors on each side. At 1, 2, 3, and 4 weeks (traction force was imposed for 4 weeks and after withdrawal of extraction force, mini-implant was retained in place for 8 weeks), dogs were sacrificed. The first and second incisors together with gingival and alveolar bone were completely resected to prepare histological specimens. Following hematoxylin-eosin staining, histological changes of tooth root and periodontal tissue were observed. RESULTS AND CONCLUSION: Compared with the control group, in the 1-week group, histological changes were primarily at the root tip and alveolar ridge crest, alveolar bone and cementum were absorbed and peridental membrane presented glassy degeneration in local region; in the 2-week group, bone resorption degree and range were obviously enlarged, and bone resorption developed from root tip, root middle part to cervical part; in the 4-week group, bone resorption was still active and the glassy degeneration of peridental membrane

  10. The expression changes of matrix metalloproteinase 2 in the periodontal tissues with implant anchorage for the anterior tooth intrusion in dogs%微种植支抗压低犬前牙过程中牙周组织基质金属蛋白酶-2的表达变化

    Institute of Scientific and Technical Information of China (English)

    刘效文; 黄敏; 赵悦

    2015-01-01

    目的:观察应用微型种植支抗使犬牙齿移动过程中基质金属蛋白酶-2(MMP-2)的表达变化,探讨其在骨改建中的作用。方法建立应用微型种植支抗压低犬上颌右侧第二切牙的实验模型。对其施加100 g的牵引力后,分别于加力后6、12、24、36周处死。选择一侧第2切牙连同牙龈、牙槽骨完整切取,进行HE染色观察组织形态,免疫组织化学检测MMP-2表达变化及时间分布特点。左侧上颌第2切牙不予施加力作为对照组,并选取同名牙周围组织进行HE及免疫组化检测。结果 HE显示对照组中犬牙齿根尖部有大量牙骨质,而被压低牙齿根尖可见牙骨质吸收。免疫组化显示牙周组织中MMP-2的表达在加力6周后开始增加,24周达最高峰,其后开始下降,结果提示差异有统计学意义(P<0.05)。结论在压低犬切牙过程中,MMP-2参与了牙周组织的改建。%Objective To observe the expression of matrix metalloproteinase 2 in the periodontal tissues with implant anchorage for the anterior tooth in dogs and to explore its role in the bone remodeling. Methods The experimental model was established by pressing down the anterior tooth with implant anchorage. After imposing 100g force, the dogs were executed sequentially at 6,12,24,36 weeks. The right second maxilla incisor with gum and the integral alveolar bone in the affected side were cut out for observation of general morphology by HE staining and detection of the change of expression and time distribution characteristics of matrix metallopmteinase 2(MMP-2) by immunohistochemistry. The left side without force imposed is chosen as the control group, and the tissue surrounding the right second maxilla incisor was explored by immunohistochemicaI detection and HE staining. Results It showed that there is a large number of bone in the tooth root apex of the control group by HE staining. However, it manifested bone absorption in the

  11. 种植体支抗结合片段弓矫治成人下颌牙列拥挤的临床应用研究%Correcting crowding of mandibular teeth by implant anchorage and partial arch wire for adult

    Institute of Scientific and Technical Information of China (English)

    郭军; 杨永进; 蔡兴伟; 李广; 黄长城

    2012-01-01

    Objective To evaluate clinical effects and the characters by micro-implant anchorage and partial arch ware correcting crowding of mandibular teeth in Class I malocclusal patients. Methods 24 Micro-implants were embedded buccal bone of mandibular first molar and mandibular second premolar of 12 Angle I malocclusal patients Ni-Ti coil spring was connected to implant and hook of distalization of mandibular lateral incisor so as to close space by contracting mandibular preteeth.Measuring buccolingual position changes of mandibular central incisors.compaction, angle of mesiodistal inclination.and moving velocity.root obsorbsion and periodontal membrane change.Evaluating anchorage by the change of mandibular first molar. Results Mandibular central incisorlingual movement and lingual inclination was 1.6mm,4.5 degree.compaction was 0.5mm,no mesiodistal inclination.course of treatment was 3.2 months, velocity of mandibular central incisor.No root obsorbsion and periodontal membrane change.Location of mandibular first molar was no changetable. Conclusion The problem of teeth crowding was resolved successfully.location of mandibualr molar and occlusion of posterion tooth was no changeable.%目的:研究安氏Ⅰ类错(牙合)患者中,采用种植体支抗结合片段弓技术,矫治成人下颌牙列 拥挤的临床效果及其作用特点.方法:选择12例成人患者,将24枚微型种植体植于下颌第一磨牙与下颌第二前磨牙之间的颊侧牙槽骨内,Ni-Ti螺旋 弹簧拉长后分别连接于种植体与下颌侧切牙远中的牵引钩,来内收下前牙关闭间隙.测量下颌中切牙的颊舌向的位置变化 、压低量、近远中倾斜度以及移动的速度,并通过治疗前后的X线片对比以观察切牙牙根有无吸收,牙周膜腔的变化情况.通过 测量下颌第一磨牙的位置变化来衡量支抗强弱.结果:下颌中切牙向舌侧移动1.6mm,舌侧倾斜4.5°,平均压低0.5mm,无近 远中倾斜,疗程3.2个

  12. 应用锥形束CT探究上颌前牙区颌骨微种植支抗钉植入的安全区%Quantitative study of maxillary anterior bone depth and labial cortical bone thickness for micro- implant anchorage placement using cone beam CT

    Institute of Scientific and Technical Information of China (English)

    赵岩; 吴平

    2012-01-01

    目的:对上颌前牙区颌骨的骨量及唇侧骨皮质厚度进行测量分析,为正畸治疗植入微种植支抗钉的安全区提供参考.方法:对25例成人患者上颌前牙区行锥形束CT扫描及三维重建,测量距上颌牙槽嵴顶3、6、9、12mm水平上颌中切牙、侧切牙、尖牙根间区近远中向、唇腭向的距离以及唇侧骨皮质厚度.结果:在距上颌牙槽嵴顶3、6、9mm水平中切牙根间近远中向距离均最宽,唇侧骨皮质均最薄;在距牙槽嵴顶9mm水平中切牙与侧切牙根间近远中向距离最窄;在4个测量水平侧切牙与尖牙根间唇侧骨皮质均最厚;唇腭向在距牙槽嵴顶9mm及以上水平,中切牙根间骨厚度最薄,中切牙与侧切牙根间骨厚度最厚.25例中仅3例前牙区各牙根长度超过12mm,在距牙槽嵴顶12mm水平测出的根间近远中向距离均较宽.结论:通过对扫描后颌骨影像的分析,明确了前牙区颌骨的骨量及唇侧骨皮质厚度,为植入微种植支抗钉的安全区提供参考.%Objective: To investigate the bone depth and labial cortical bone thickness of maxillary anterior interdental area for orthodontic micro-implant anchorage. Methods; Maxillary anterior alveolar bone of 25 adults was scanned and reconstructed by cone beam CT, the mesio-distal interdental distance, labial-palatal bone depth and labial cortical bone thickness were measured at 3, 6, 9 and 12 mm from the alveolar crest between upper anterior dental roots. Results; The mesio-distal distance between central incisors was the widest in all measurement levels, while the labial cortical bone thickness was the thinnest. At the 9 mm-level, the shortest mesio-distal distance was between the roots of central and lateral incisors. The labial cortical bone thickness between lateral incisors and canines was the thickest in all measurement levels. At or above the 9 mm-level, the labial-palatal bone depth was the thinnest between central incisors, but the thickest

  13. 微型种植体支抗辅助牵引成骨重建上颌骨部分缺损的效果评估%Mini-screw implant anchorage-assisted distraction osteogenesis for reconstruction of partial maxillary defect

    Institute of Scientific and Technical Information of China (English)

    冯贻苗; 沈国芳; 房兵; 毛丽霞; 娄新田

    2009-01-01

    PURPOSE:To evaluate the usefulness of self-made distraction osteogenesis instrument by orthodontic technique and mini-screw implant anchorage-assisted distraction osteogenesis(DO) to reconstruct partial maxillary defects. METHODS: Eight patients suffering from partial maxillary defects were selected. Their ages ranged from 19 to 43 years and the average age was 33.2 years. There were 5 males. After a special instrument was fabricated, elastic force trifocal distraction was performed by mini-implant borne aneborage. Three months later the implants were implanted in the two distracted region and the prosthetic restorations were finished finally. RESULTS: In the areas of distraction osteogenesis, ossifications were fine and alveolar bones were completed. The partial maxillary defects were repaired with the implant technique and the prosthodontie technique, and favourable occlusion was obtained. CONCLUSION: Combined orthodontic and DO techniques can reconstruct partial maxillary defect successfully and restore the complicated anatomical contour of the maxilla, especially the dental-alveolar bone.%目的:评价正畸技术自制牵引成骨装置及微型种植体支抗辅助弹力牵引重建上颌骨部分缺损的疗效.方法:选择5例上颌骨部分缺损病例,均为男性,年龄19~43岁,平均33.2岁.制作特殊的牵引装置.采用微型种植体支抗辅助支持的弹力牵引方式,进行三焦点式牵引成骨.3个月后,在两侧牵引区植入种植体,进行牙列修复.结果:骨缺损区牵引成骨后成骨良好,形成完整的牙槽嵴,可应用种植和托牙技术进行牙列修复,恢复良好的咬合关系.结论:对上颌骨部分骨缺损病例,可应用正畸技术和牵引成骨技术联合治疗,以恢复颌骨复杂的解剖结构,尤其是牙槽嵴,为牙列修复提供必备的条件.

  14. "Dinosaurs." Kindergarten. Anchorage School District Elementary Science Program.

    Science.gov (United States)

    Herminghaus, Trisha, Ed.

    This unit contains 15 lessons on dinosaurs for kindergarten children. It provides a materials list, supplementary materials list, use of process skill terminology, unit objectives, vocabulary, six major dinosaurs, and background information. Lessons are: (1) "Webbing"; (2) "Introduction to the Big Six"; (3) "Paleontology and Fossils"; (4) "How Big…

  15. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, ANCHORAGE, ALASKA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — FEMA Framework Basemap datasets comprise six of the seven FGDC themes of geospatial data that are used by most GIS applications (Note: the seventh framework theme,...

  16. Mini-implants for direct or indirect orthodontic anchorage

    NARCIS (Netherlands)

    Ren, Yijin

    2009-01-01

    DATA SOURCES: Studies were sourced using Medline, the Cochrane Library and hand searches of key orthodontic journals. STUDY SELECTION: The review was restricted to peer-review articles (randomised controlled studies, prospective clinical studies and retrospective clinical studies) dealing with mini-

  17. Metabolism Kinetics of Glucose in Anchorage-dependent Cell Cultures

    Institute of Scientific and Technical Information of China (English)

    孙祥明; 张元兴

    2001-01-01

    The kinetic model of glucose metabolism was established and successfully applied to batchcultures of rCHO and rBHK cells. It was found that a large amount of glucose was utilized for cellmaintenance, and the overwhelming majority of maintenance energy from glucose was by its anaerobicmetabolism in both rBHK and rCHO cell cultures. The overall maintenance coefficients from aerobicmetabolism were 1.9×10-13 mmol/(cell.h) for rCHO cells and 7×10-13 mmol/(cell.h) for rBHK cells. Inaddition, all Go/T and Eo/T gradually increased with the same trend as the cell growth in the culture ofboth rCHO and rBHK cells. The overall molecule yield coefficients of lactate to glucose were 1.61 for rCHO cells and 1.38 for rBHK cells. The yield coefficients of cell to glucose were 4.5×108 cells/mmol for rCHO cells and 1.9 × 108 cells/mmol for rBHK cells, respectively.

  18. Vector control in internal midface distraction using temporary anchorage devices.

    Science.gov (United States)

    Francis, Cameron; Rommer, Elizabeth; Mancho, Salim; Carey, Joseph; Hammoudeh, Jeffrey A; Urata, Mark M

    2012-11-01

    Le Fort III and monobloc distraction osteogenesis serve as the primary surgical treatment for children with severe midface hypoplasia. The orbital retrusion and class III malocclusion of patients with midface hypoplasia is best addressed with bodily advancement of the midface segment parallel to the cephalometric Frankfort horizontal plane. Use of internal distraction devices allows for advancement of the midface without extensive external hardware but comes at the cost of less vectorial control, resulting in a distraction vector that can cause a clockwise rotation of the entire midface or frontofacial component creating hollow appearing orbits. To counteract this clockwise rotation, we have developed a technique using orthodontic microimplants to anchor interarch class III relationship elastics. We report our experiences with this technique on a cadaveric model and as a case series of 17 patients who underwent midface distraction. A Le Fort III distraction procedure was carried out on a cadaver, and the orbital height was measured at 0-, 10-, and 20-mm distraction advancement with and without elastics in a class III relationship. Improvement of both subjective hollow appearance of the orbits and objective measurement of the orbital height with class III relationship elastics demonstrated the efficacy of class III relationship elastics in counteracting the clockwise rotation of the midface segment. A review of 17 patients with midface or frontofacial hypoplasia treated with Le Fort III or monobloc distraction with simultaneous microimplant anchored class III relationship elastics revealed correction of malocclusion and improved midface projection without significant increase in vertical height of the orbits.

  19. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, MUNICIPALITY OF ANCHORAGE, ALASKA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  20. Process entanglement as a neuronal anchorage mechanism to rough surfaces

    Science.gov (United States)

    Sorkin, Raya; Greenbaum, Alon; David-Pur, Moshe; Anava, Sarit; Ayali, Amir; Ben-Jacob, Eshel; Hanein, Yael

    2009-01-01

    The organization of neurons and glia cells on substrates composed of pristine carbon nanotube islands was investigated using high resolution scanning electron microscopy, immunostaining and confocal microscopy. Neurons were found bound and preferentially anchored to the rough surfaces; moreover, the morphology of the neuronal processes on the small, isolated islands of high density carbon nanotubes was found to be conspicuously curled and entangled. We further demonstrate that the roughness of the surface must match the diameter of the neuronal processes in order to allow them to bind. The results presented here suggest that entanglement, a mechanical effect, may constitute an additional mechanism by which neurons (and possibly other cell types) anchor themselves to rough surfaces. Understanding the nature of the interface between neurons and carbon nanotubes is essential to effectively harness carbon nanotube technology in neurological applications such as neuro-prosthetic and retinal electrodes.

  1. Field contrast test and mechanism analysis on anchorage performance of anti-floating anchors with two different materials%两种不同材质抗浮锚杆锚固性能的现场对比试验研究与机理分析

    Institute of Scientific and Technical Information of China (English)

    白晓宇; 张明义; 闫楠

    2015-01-01

    为深入研究中风化花岗岩中以全螺纹GFRP筋材为杆体的全长黏结抗浮锚杆锚固机理及破坏机制,进行了螺纹GFRP抗浮锚杆与螺纹钢抗浮锚杆现场拉拔试验。试验结果表明,GFRP抗浮锚杆的极限抗拔承载力高于钢筋抗浮锚杆;相同荷载水平,相同位置处GFRP锚杆的轴力大于钢筋锚杆,钢筋锚杆轴力沿深度衰减的速率比GFRP锚杆快;GFRP锚杆剪应力峰值点较钢筋锚杆更明显,钢筋锚杆的剪应力比GFRP锚杆发挥早,GFRP锚杆的峰值剪应力比钢筋锚杆大;就砂浆与围岩界面的平均黏结强度而言,GFRP抗浮锚杆高于钢筋抗浮锚杆;GFRP抗浮锚杆以杆体材料剪切破坏为主,而螺纹钢锚杆的破坏是锚固体与围岩界面产生剪切滑移破坏。%The pull-out contrast tests of threaded GFRP anti-floating anchor and threaded steel anchor rod were conducted to study the anchoring mechanism and the failure mechanism of full-length bonding anti-floating anchor in the moderately weathered granite. The following conclusion can be drawn:(1) The ultimate anti-lifting bearing capacity of GFRP anti-floating anchor is higher than that of steel anchor rod. (2) The axial force of GFRP anti-floating anchor is greater than that of steel anchor rod at the same loading level and the same position, and the axial force in steel anchor rod attenuates quickly along the depth compared to that of GFRP anchor rod. (3) The shear stress peak value point of GFRP anchor rod is more evident than that of steel anchor rod. However, the shear stress of steel anchor rod comes into play earlier than GFRP anchor, and the peak shear stress of GFRP anchor is larger than steel anchor rod. ( 4 ) The average bond strength of GFRP anti-floating anchor is higher than that of steel anti-floating anchor in terms of the mortar-rock interface. (5) GFRP anti-floating anchors mainly exhibit shear failure and the shear slip failure may occur at the anchorage section if the

  2. 微型种植体支抗-骨界面压力侧和非压力侧的组织学研究%A histological study on the bone-implant interface of the mini-screw implant anchorage

    Institute of Scientific and Technical Information of China (English)

    冯贻苗; 房兵; 娄新田; 吴勇; 江凌勇

    2011-01-01

    目的 研究在不同愈合时间和负载条件下微型种植体支抗-骨界面压力侧和非压力侧的组织学变化.方法 选用纯种Beagle犬8只,在其上颌根间牙槽骨中植入86颗微型种植体支抗,分别进行即刻负载、愈合2周、愈合4周、愈合12周后加载150 g和300 g牵引力,定期注射荧光标志物,加载2个月后处死动物.标记种植体的压力侧和非压力侧,两侧分别进行种植体颈部骨结合率(BIC)、骨充填率(BSA)和矿物沉积率(MAR)的测量以及HE染色组织形态观察,以BIC和BSA作为骨整合能力的观察指标.结果 即刻负载组和愈合2周负载300克组压力侧的骨整合能力、矿物沉积率和骨改建活跃程度均小于非压力侧,其余各组则相反.不同负载力值组间比较无显著性差异.结论 微型种植体支抗-骨界面颈部即刻负载时压力侧的骨整合和骨改建较非压力侧低,随着愈合时间的延长,压力侧相对增强,非压力侧相对降低,而负载力值对界面的影响较小.%Objective To investigate the histological difference at the bone-implant interface between pressure and non-pressure sides of the mini-screw implant anchorage (MIA) under the condition of different loading force and heeling time. Methods Eighty-six MIAs were inserted in the maxillary alveolar bone between the dental roots in 8 beagles. Healing after 0, 2, 4, 12 weeks, 150 g and 300 g forces were loaded perpendicularly to the implants and fluorochrome was injected. Two months later, all dogs were sacrificed. The slices of MIA on the pressure and non-pressure sides were labeled. Bone implant contact ratio(BIC), bone surface area(BSA) and mineral apposition rate (MAR) were measured and histological observations were carried out. Results BIC, BSA, MAR and bone remodeling on the pressure side were lower than those on the non-pressure side in the immediate loading group and the group healing after 2 weeks with 300 g force, while the reverse result

  3. 应用种植支抗大鼠牙齿移动压力侧与牙齿自然萌出过程中骨保护素及RANKL表达的比较%Comparison of osteoprotegerin and RANKL expresssions during orthodontic tooth movement using implant anchorage and natural tooth eruption in rats

    Institute of Scientific and Technical Information of China (English)

    张红艳; 赵悦

    2013-01-01

    Objective:To explore whether osteoprotegerin (OPG) and receptor activator of nuclear factor kappa-B ligand (RANKL) expressed differentially during orthodontic tooth movement using implant anchorage and natural tooth eruption in rats.Methods:By means of HE staining,X-ray photography and immunohistochemistriy,the morphology of the mandibular first molars and expressions of OPG and RANKL in experimental rats receivd orthodontic force using implant anchroage for 2,4,7 and 14 days,and control rats aged postnatal days 0,7,10,15 and 21.Results:The radiophotographs showed that the mandibular first molars were pulled toward mesiocclusion with presence of orthodontic force.The amounts of osteoblasts and osteoclasts were similar both in experimetnal and control animals.Strong expressions of OPG and RANKL were detected both in experimental and control animals.Conclusion:The similar trend of OPG and RANKL expressions during OTM and tooth eruption are in coincidence with alveolar bone remodeling.%目的:比较应用种植支抗使大鼠牙齿移动与牙齿自然萌出过程中骨保护素及破骨细胞核因子B受体活化因子配基(RANKL)表达变化.方法:建立应用种植支抗牵引移动大鼠下颌第1磨牙的动物实验组.对照组取出生后0、7、10、15d及21 d的SD乳鼠处死,实验组分别于加力牵引2、4、7d及14d后,解剖分离大鼠下颌骨,拍X线片,常规H-E染色观察大体组织形态,免疫组织化学检测骨保护素及RANKL表达.结果:应用种植支抗牵引大鼠牙齿移动组中,X线示牵引的第1磨牙向近中移动,H-E染色示牙齿自然萌出组中的成骨细胞及破骨细胞强阳性表达,应用种植支抗牙齿移动组中成骨细胞及破骨细胞表达较多.免疫组织化学显示实验组和对照组骨保护素及RANKL阳性表达.结论:在牙齿自然萌出及正畸牙移动过程中,骨保护素及RANKL表达变化相似,其变化规律与牙槽骨改建过程一致.

  4. Logistic regression analysis of risk factors associated with the stability of miniscrews used as orthodontic anchorage%口腔正畸患者微型种植体支抗钉稳定性危险因素的 Logistic 回归分析

    Institute of Scientific and Technical Information of China (English)

    戴兵; 杨柏霞; 王海艳

    2016-01-01

    Objective:To evaluate risk factors that affect the stability of miniscrew used asorthodontic anchorage.Methods:A total of eighty malocclusional patients from August 2012 to February 2015 in our hospital were enrolled (inclusion criteria:malocclu-sional patients without severe heart,brain and lung disease,without severe liver and kidney disfunction,without neural and mental dis-eases,without contraindications for surgery and tooth extraction)and divided into two groups based on whether the minicrews were loos-en,lost,shifted or not:stable group (57 patients with 241 miniscrews)and unstable group (23 patients with 28 miniscrews).Ten po-tential risk factors,including age,gender,length of minicrews,oral hygiene status,inflammation of the peri-implant tissue,sites and an-gle of loading,the time of initial load application,methods and duration of loading,were firstly screened using univariate analysis,and the significant risk factors were further determined by employing multiple logistic regression analysis.Results:5 significant risk factors were found by univariate analysis,which were age,the time of initial load application,the lasting time of loading,oral hygiene status and Inflammation of the peri-implant tissue.Further study with multiple logistic regression analysis indicated that age was positively associat-ed with the stability of minicrews,while the time of initial load application,lasting time of loading,oral hygiene status and Inflammation of the peri-implant tissue were negatively associated with the stability of minicrews.Conclusion:Age,the time of initial load applica-tion,lasting time of loading,oral hygiene status and Inflammation of the peri-implant tissue were risk factors associated with the stability of minicrews.This information will help to optimize the therapeutic strategies and improve the clinical efficacy.%目的:探讨影响微种植体支抗钉稳定性的危险因素。方法:对80例错牙合患者进行微型种植体支抗正畸治疗

  5. Facemask therapy with miniplate implant anchorage in a patient with maxillary hypoplasia

    Institute of Scientific and Technical Information of China (English)

    ZHOU Yan-heng; DING Peng; LIN Ye; QIU Li-xin

    2007-01-01

    @@ Areverse headgear is thought to be an effective treatment approach for skeletal class Ⅲ malocclusion with retruded maxilla. Clinical studies have shown that the changes of occlusion are a combination of skeletal and dental changes: forward movement of the maxilla, proclination of the maxillary incisors, clockwise rotation of the mandible, and retroclination of the mandibular incisors.1,2 However, the undesirable dental effects, such as excessive mesial movement and extrusion of maxillary molars and labial tipping of maxillary incisors, have been reported.

  6. 76 FR 15246 - Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI

    Science.gov (United States)

    2011-03-21

    ... regarding our public dockets in the January 17, 2008 issue of the Federal Register (73 FR 3316). Public... coordinates referenced use datum: NAD 83. Dated: March 3, 2011. Daniel A. Neptun, Rear Admiral, U.S....

  7. 76 FR 80394 - Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK

    Science.gov (United States)

    2011-12-23

    ... National Park Service Notice of Inventory Completion: Alaska State Office, Bureau of Land Management..., Bureau of Land Management has completed an inventory of human remains, in consultation with the... culturally affiliated with the human remains may contact the Alaska State Office, Bureau of Land...

  8. INFLUENCE OF PIT WALL ANCHORAGE ONTO ADDITIONAL DEFORMATIONS OF EXISTING BUILDINGS

    Directory of Open Access Journals (Sweden)

    Kubetskiy Valeriy Leonidovich

    2012-07-01

    Assessment of additional projected deformations of buildings located in close proximity to pits is exemplified by the specific structure of the pit support system that has active PIT [1] anchors. The authors also consider the influence produced by the structure of anchors onto the two buildings located within the area of influence of the excavation works and protected by the anchors installed underneath the foundations of the two adjacent buildings.

  9. 77 FR 43514 - Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI

    Science.gov (United States)

    2012-07-25

    ... Rhode Island Sound, RI,'' in the Federal Register (76 FR 15246). We received nine comments on the... Sound, RI AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The Coast Guard is removing an obsolete... Island Sound south of Brenton Point, Rhode Island, for use by vessels waiting to enter Narragansett...

  10. 77 FR 19155 - Federal Motor Vehicle Safety Standards; Seat Belt Assembly Anchorages; Incorporation by Reference

    Science.gov (United States)

    2012-03-30

    ... published on April 11, 2000 (65 FR 19477-78). FOR FURTHER INFORMATION CONTACT: For non-legal issues: Ms... the FAD is acceptable. In comparison, FMVSS No. 208, ``Occupant crash protection,'' at S10.4.2.1... NPRM that, among other matters, proposed to require passenger seat belts on motorcoaches (75 FR...

  11. 49 CFR 571.210 - Standard No. 210; Seat belt assembly anchorages.

    Science.gov (United States)

    2010-10-01

    ... protection requirements of S5.1 of Standard No. 208 (49 CFR 571.208). S4.1.3School bus passenger seats. S4.1... shall be Type 1 or Type 2 as defined in S3 of FMVSS No. 209 (49 CFR 571.209). S4.1.3.2Type 2 seat belt... structure. Small occupant seating position is as defined in 49 CFR 571.222. S4. Requirements. S4.1Type.......

  12. Group Distal Movement of Teeth using Micro-Screw–Implant Anchorage-A Case Report

    OpenAIRE

    Kalarickal, Biju

    2014-01-01

    This case report describes a case of orthodontic tooth movement of a 29-year-old female patient utilizing maxillary posterior edentulous area. Micro-implants were placed at buccal edentulous spaces and inter-radicular space for retraction of entire maxillary dentition. An overjet reduction of 8mm and good posterior occlusion were achieved.

  13. Electric-field-enhanced nutrient consumption in dielectric biomaterials that contain anchorage-dependent cells.

    Science.gov (United States)

    Belfiore, Laurence A; Floren, Michael L; Belfiore, Carol J

    2012-02-01

    This research contribution addresses electric-field stimulation of intra-tissue mass transfer and cell proliferation in viscoelastic biomaterials. The unsteady state reaction-diffusion equation is solved according to the von Kármán-Pohlhausen integral method of boundary layer analysis when nutrient consumption and tissue regeneration occur in response to harmonic electric potential differences across a parallel-plate capacitor in a dielectric-sandwich configuration. The partial differential mass balance with diffusion and electro-kinetic consumption contains the Damköhler (Λ(2)) and Deborah (De) numbers. Zero-field and electric-field-sensitive Damköhler numbers affect nutrient boundary layer growth. Diagonal elements of the 2nd-rank diffusion tensor are enhanced in the presence of weak electric fields, in agreement with the formalism of equilibrium and nonequilibrium thermodynamics. Induced dipole polarization density within viscoelastic biomaterials is calculated via the real and imaginary components of the complex dielectric constant, according to the Debye equation, to quantify electro-kinetic stimulation. Rates of nutrient consumption under zero-field conditions are described by third-order kinetics that include local mass densities of nutrients, oxygen, and attached cells. Thinner nutrient boundary layers are stabilized at shorter dimensionless diffusion times when the zero-field intra-tissue Damköhler number increases above its initial-condition-sensitive critical value [i.e., {Λ(2)(zero-field)}(critical)≥53, see Eq. (23)], such that the biomaterial core is starved of essential ingredients required for successful proliferation. When tissue regeneration occurs above the critical electric-field-sensitive intra-tissue Damköhler number, the electro-kinetic contribution to nutrient consumption cannot be neglected. The critical electric-field-sensitive intra-tissue Damköhler number is proportional to the Deborah number.

  14. Neural maintenance roles for the matrix receptor dystroglycan and the nuclear anchorage complex in Caenorhabditis elegans

    NARCIS (Netherlands)

    Johnson, R.P.; Kramer, J.M.

    2012-01-01

    Recent studies in Caenorhabditis elegans have revealed specific neural maintenance mechanisms that protect soma and neurites against mispositioning due to displacement stresses, such as muscle contraction. We report that C. elegans dystroglycan (DG) DGN-1 functions to maintain the position of lumbar

  15. Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells

    Directory of Open Access Journals (Sweden)

    Xuesong Liu

    2001-01-01

    Full Text Available The serine/threonine kinases, Akti/PKBα, Akt2/PKBβ, and Akt3/PKBγ, play a critical role in preventing cancer cells from undergoing apoptosis. However, the function of individual Akt isoforms in the tumorigenicity of cancer cells is still not well defined. In the current study, we used an AM antisense oligonucleotide (AS to specifically downregulate Akti protein in both cancer and normal cells. Our data indicate that AM AS treatment inhibits the ability of MiaPaCa-2, H460, HCT-15, and HT1080 cells to grow in soft agar. The treatment also induces apoptosis in these cancer cells as demonstrated by FRCS analysis and a caspase activity assay. Conversely, Akti AS treatment has little effect on the cell growth and survival of normal human cells including normal human fibroblast (NHF, fibroblast from muscle (FBM, and mammary gland epithelial 184135 cells. In addition, AM AS specifically sensitizes cancer cells to typical chemotherapeutic agents. Thus, Akti is indispensable for maintaining the tumorigenicity of cancer cells. Inhibition of AM may provide a powerful sensitization agent for chemotherapy specifically in cancer cells.

  16. Fatigue of threaded rods in cable anchorages due to Vortex shedding

    NARCIS (Netherlands)

    Maljaars, J.; Snijder, H.H.

    2013-01-01

    The 'Hovenring' is a bicycle roundabout flyover built as a signature bridge with a central steel pylon carrying a circular bridge deck suspended through stay-cables. Shortly after installation of the bridge, the stay-cables turned out to vibrate in the wind due to vortex shedding. These vibrations h

  17. Anchorage of titanium implants with different surface characteristics: an experimental study in rabbits

    DEFF Research Database (Denmark)

    Gotfredsen, K; Berglundh, T; Lindhe, J

    2000-01-01

    in group B were 9 and 12 weeks. The tibiae were removed, and each implant site was dissected, fixed, and embedded in light-curing resin. Ground sections were made, and the peri-implant bone was analyzed using fluorescence and light microscopy. RESULTS: The turned implants had the lowest Sa and Sy values...

  18. A novel Fmoc-based anchorage for the synthesis of protected peptides on solid phase.

    Science.gov (United States)

    Liu, Y Z; Ding, S H; Chu, J Y; Felix, A M

    1990-02-01

    A novel bifunctional compound, 9-(hydroxymethyl)-2-fluoreneacetic acid, was synthesized, coupled to benzhydrylamine-resin, and evaluated for its application to the solid phase synthesis of protected peptide fragments. Anchor-bond cleavage was achieved with 15% piperidine/DMF. A protected heptapeptide, Boc-Val-Val-Ser(Bzl)-His(Tos)-Phe-Asn-Lys-(Z)-OH, corresponding to the sequence (1-7) of rat-transforming growth factor-alpha, was synthesized using this new support with an overall yield of 46%.

  19. F00267: NOS Hydrographic Survey , Chesapeake Bay Hurricane Anchorages, Virginia, 1984-06-21

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  20. H08203: NOS Hydrographic Survey , Anchorage, Alaska, 1955-05-27

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  1. Being physically active : a bodily anchorage on the journey for recovery in mental ill-health

    OpenAIRE

    Lassenius, Oona

    2014-01-01

    Suffering from mental ill-health does not merely involve mental distress; it also often comprises deteriorated physical health. The physical consequences can be of a severe nature and may lead to premature death. Since physical inactivity has been identified as a critical health risk factor, there is an imperative need to support physical activity in persons with mental ill-health. The benefits of being physically active for persons with mental ill-health are many, but there are also consider...

  2. A role for collagen XXIII in cancer cell adhesion, anchorage-independence, and metastasis

    OpenAIRE

    Spivey, Kristin A.; Chung, Ivy; Banyard, Jacqueline; Adini, Irit; Feldman, Henry A.; Bruce R Zetter

    2011-01-01

    Collagen XXIII is a transmembrane collagen previously shown to be upregulated in metastatic prostate cancer that has been used as a tissue and fluid biomarker for non-small cell lung cancer and prostate cancer. To determine whether collagen XXIII facilitates cancer cell metastasis in vivo and to establish a function for collagen XXIII in cancer progression, collagen XXIII knockdown cells were examined for alterations in in vivo metastasis as well as in vitro cell adhesion. In experimental and...

  3. 33 CFR 401.65 - Communication-ports, docks and anchorages.

    Science.gov (United States)

    2010-07-01

    ... giving its destination and the expected time of arrival at the next check point. (c) Every vessel... the expected time of arrival at the next check point. (68 Stat. 93-96, 33 U.S.C. 981-990, as...

  4. Ultimate Bearing Strength of Post-tensioned Local Anchorage Zones in Lightweight Concrete

    OpenAIRE

    Axson, Daniel Peter

    2008-01-01

    Currently, NCHRP Report 356 has published an equation to estimate the ultimate strength of the local zone in normal weight concrete. The local zone is the area of concrete directly ahead of the bearing plate. The equation can be broken into two distinct parts: unconfined bearing strength of concrete enhanced by the A/Ab ratio and the enhancement of strength due to the presence of confining. Research has shown that the strength enhancement of the A/Ab ratio and confining reinfor...

  5. Salmon habitat improvement reconnaissance, Prince William Sound, Cordova and Anchorage districts, September 1985

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report is on the salmon habitat improvement reconnaissance in the Prince William sound, Alaska. The purpose of the trip was to discover new habitat improvement...

  6. CALCULATION ASSESSMENT OF ANCHORAGE IN CONCRETE FOR FIBERGLASS REINFORCEMENT MANUFACTURED IN THE REPUBLIC OF BELARUS

    OpenAIRE

    E. Ya. Sadin

    2016-01-01

    The paper analyzes advantages and disadvantages of composite reinforcement while reinforcing concrete structures. Results of experimental investigations on adhesion strength of fiberglass reinforcement manufactured in the Republic of Belarus with concrete have been given in the paper. The paper contains an analysis pertaining to the influence of concrete contact diameter and length of fiberglass reinforcing bars on strength and deformability of adhesion with concrete. Failure behavior of prot...

  7. Mandibular implant-retained overdenture: a clinical trial of two anchorage systems.

    Science.gov (United States)

    Menicucci, G; Lorenzetti, M; Pera, P; Preti, G

    1998-01-01

    This in-vivo study aimed to investigate the load on the working-side implant and on the edentulous distal mucosa of the nonworking side in a mandibular implant-retained overdenture (MIR-OVD) anchored to 2 implants by either a ball- or a clips-and-bar attachment. Three female patients were provided with duplicate dentures anchored in the 2 ways. Strain on the implant was investigated using a strain-gauged abutment, and load on the mucosa was measured using a suitably placed load cell. Ball attachments appeared to provide greater stability to the MIR-OVD, since load was more evenly distributed onto the distal mucosa of both sides. When the MIR-OVD was bar-anchored, axial load on the working-side abutment increased. PMID:9857597

  8. Mandibular implant-retained overdenture: finite element analysis of two anchorage systems.

    Science.gov (United States)

    Menicucci, G; Lorenzetti, M; Pera, P; Preti, G

    1998-01-01

    Transmission of masticatory load in mandibular implant-retained overdentures was evaluated using a three-dimensional finite element model. The reaction forces on the distal edentulous mucosa and the stress on the perimplant bone were compared in overdentures retained either by two ball attachments or by two clips on a bar connecting two implants. In the finite element model, a 35 N load on the first mandibular molar induced a greater reaction force on the distal edentulous ridge mucosa of the nonworking side when the overdenture was anchored by ball attachments than with the clips/bar attachment. Stress on peri-implant bone was greater with the clips/bar attachment than with the ball attachment. PMID:9638007

  9. Ancient technology of jetties and anchorage system along the Saurastra coast, India

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh

    the manufacturing stage and not during the anchoring processes. A composite anchor made of limestone is another noteworthy find from the site. The presence of a few unfinished anchors at Gogha and Hathab, which lie submerged in 5–7 m. water during high tide... (1966) Excavations at Dwarka, Pune: Deccan College Postgraduate and Research Institute. Bhan, K.K. (2006) ‘Towards an Understanding of Medieval Glazed Pottery Manufacture from Lakshkarshah, Khambhat, Gujarat’, Man and Environment, vol. XXXI, no. 2, pp...

  10. Ancient anchorage systems in India with reference to the Gujarat coast

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh; Tripati, S.

    types such as composite, Indo-Arab and ring stone type. They are of various sizes weighing between 20 and >1000 kgs. The sizes indicate the uses of various sizes and types of boats visited this coast or were manufactured along this coast during... during the manufacturing stage and not during the anchoring processes. A composite anchor made of lime stone is another noteworthy finds from the site. A few anchors unfinished were also found from Gogha and Hathab. However, these anchors submerge in 5...

  11. 33 CFR 110.6 - Portland Harbor, Portland, Maine (between Little Diamond Island and Great Diamond Island).

    Science.gov (United States)

    2010-07-01

    ... Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage.... Fixed mooring piles or stakes are prohibited. The anchoring of vessels and placing of temporary...

  12. NUMERICAL ANALYSIS OF ANCHORAGE PERFORMANCE ON SAND CONSOLIDATED ANCHORAGE PRESTRESSED BOLT BY PARTICLE FLOW CODE%砂固结预应力锚杆锚固性能的颗粒流数值分析

    Institute of Scientific and Technical Information of China (English)

    张思峰; 周健; 李艳梅

    2007-01-01

    基于颗粒流理论,建立分析砂固结预应力锚杆锚固性能的颗粒流数值分析模型.通过数值模型试验,对砂固结预应力锚杆的荷载-位移特性以及砂颗粒在载荷作用下的应力、位移及孔隙率变化规律等细观特性进行分析.分析结果表明:加载初期挡板位移增长较快;而随着荷载逐级增大,表现出位移增量的逐级收敛性;随挡板移动,砂颗粒内部孔隙率及其相互之间的接触力从距离挡板由近及远分别经历孔隙率减小、颗粒接触力增大的过程,并最终分别趋于稳定.通过与室内模型试验结果相对比,验证数值模拟的正确性,并通过对挡板埋置深度、砂体初始孔隙率、挡板宽度等因素的分析,探讨影响砂固结预应力锚杆锚固性能的一些因素.

  13. 76 FR 35742 - Superfund Site, New Bedford Harbor, New Bedford, MA: Anchorage Ground and Regulated Navigation Area

    Science.gov (United States)

    2011-06-20

    ... Register (76 FR 20287). We received no comments on the proposed rule. A public meeting was not requested....S. Coast Guard. Dated: June 6, 2011. D.A. Neptun, Rear Admiral, U.S. Coast Guard, Commander,...

  14. Accelerated Sorption Diffusion for Cu(II) Retention by Anchorage of Nano-zirconium Dioxide onto Highly charged Polystyrene Material

    Science.gov (United States)

    Zhang, Qingrui; Du, Qing; Jiao, Tifeng; Teng, Jie; Sun, Qina; Peng, Qiuming; Chen, Xinqing; Gao, Faming

    2015-01-01

    The development of nanocomposite with strong adsorption ability exhibits great potential applications for environmental remediation. However, the pore blocking in preparation frequently constrains sorption diffusion, resulting in low utilization efficiency. Here we synthesized a new nano-ZrO2/Polystyrene (NZO-PS) material tailored with a specific fixed SO3-Na group to enhance Cu(II) removal. The NZO-PS exhibits efficient Cu(II) sequestration in a wide pH range (3.0–6.5) and preferential sorption performances. The efficient kinetic behavior and column applicability suggest the blocked pore channel is not a matter when presence of negatively charged moiety, which accelerates Cu(II) sorption diffusion and enrichment toward target active site. Moreover, the exhausted NZO-PS can be readily regenerated through HCl-NaCl binary solution. The preparation route can be extended to synthesize other functional composited materials. Simultaneously, the characteristics of simplicity, high-yield and regeneration provide some promising industrial merits. PMID:26184921

  15. Treatment Approach for Maxillary Hypoplasia in Cleft Patients: Class III Elastics with Skeletal Anchorage (Report of Two Cases)

    Science.gov (United States)

    Jahanbin, Arezoo; Kazemian, Mozhgan; Saeedi-Pouya, Iman; Eslami, Neda; Shafaee, Hooman

    2016-01-01

    Introduction: Treatment of cleft lip and palate patients requires a multidisciplinary plan. These patients usually have a hypoplastic maxilla due to the prior surgical scars. Orthognathic surgery to advance the maxilla in these patients is not very efficient; therefore, orthopedic interventions during an appropriate age seems to be essential. Case Report: In this article, two cleft lip and palate patients have been treated with Class III elastics anchored to the maxillary posterior and mandibular anterior miniplates in order to induce maxillary advancement. Conclusion: Both cases showed a significant improvement in their profiles with minimal dentoalveolar compensations. A counterclockwise rotation of the mandible occurred. PMID:27602343

  16. Orthogonal Click Conjugation to the Liposomal Surface Reveals the Stability of the Lipid Anchorage as Crucial for Targeting.

    Science.gov (United States)

    Fritz, Thomas; Voigt, Matthias; Worm, Matthias; Negwer, Inka; Müller, Sophie S; Kettenbach, Kathrin; Ross, Tobias L; Roesch, Frank; Koynov, Kaloian; Frey, Holger; Helm, Mark

    2016-08-01

    Synthetic access to multiple surface decorations are a bottleneck in the development of liposomes for receptor mediated targeting. This opens a complex multiparameter space, exploration of which is severely limited in terms of sample numbers and turnaround times. Here, we unlock this technological barrier by a combination of a milligram-scale liposome formulation using dual centrifugation and orthogonal click chemistry on the liposomal surface. Application of these techniques to conceptually new amphiphilic compounds, which feature norbornene and alkyne groups at the apex of sterically stabilizing, hyperbranched polyglycerol moieties, revealed a particular influence of the membrane anchor of functional amphiphiles. Folic acid residues clicked to cholesterol-based amphiphiles were inefficient in folate-mediated cell targeting, while dialkyl-anchored amphiphiles remained stable in the liposomal membrane and imparted efficient targeting properties. These findings are of specific importance considering the popularity of cholesterol as a lipophilic anchor. PMID:27403892

  17. Measurement of strain distribution in cortical bone around miniscrew implants used for orthodontic anchorage using digital speckle pattern interferometry

    Science.gov (United States)

    Kumar, Manoj; Agarwal, Rupali; Bhutani, Ravi; Shakher, Chandra

    2016-05-01

    An application of digital speckle pattern interferometry (DSPI) for the measurement of deformations and strain-field distributions developed in cortical bone around orthodontic miniscrew implants inserted into the human maxilla is presented. The purpose of this study is to measure and compare the strain distribution in cortical bone/miniscrew interface of human maxilla around miniscrew implants of different diameters, different implant lengths, and implants of different commercially available companies. The technique is also used to measure tilt/rotation of canine caused due to the application of retraction springs. The proposed technique has high sensitivity and enables the observation of deformation/strain distribution. In DSPI, two specklegrams are recorded corresponding to pre- and postloading of the retraction spring. The DSPI fringe pattern is observed by subtracting these two specklegrams. Optical phase was extracted using Riesz transform and the monogenic signal from a single DSPI fringe pattern. The obtained phase is used to calculate the parameters of interest such as displacement/deformation and strain/stress. The experiment was conducted on a dry human skull fulfilling the criteria of intact dental arches and all teeth present. Eight different miniscrew implants were loaded with an insertion angulation of 45 deg in the inter-radicular region of the maxillary second premolar and molar region. The loading of miniscrew implants was done with force level (150 gf) by nickel-titanium closed-coil springs (9 mm). The obtained results from DSPI reveal that implant diameter and implant length affect the displacement and strain distribution in cortical bone layer surrounding the miniscrew implant.

  18. Three-Dimensional Finite Element Analysis of Anterior Single Implant-Supported Prostheses with Different Bone Anchorages

    OpenAIRE

    Fellippo Ramos Verri; Joel Ferreira Santiago Júnior; Daniel Augusto de Faria Almeida; Ana Caroline Gonçales Verri; Victor Eduardo de Souza Batista; Cleidiel Aparecido Araujo Lemos; Pedro Yoshito Noritomi; Eduardo Piza Pellizzer

    2015-01-01

    The aim of this study was to evaluate the stress distribution of monocortical and bicortical implant placement of external hexagon connection in the anterior region of the maxilla by 3D finite element analysis (FEA). 3D models were simulated to represent a bone block of anterior region of the maxilla containing an implant (4.0 × 10.0 mm) and an implant-supported cemented metalloceramic crown of the central incisor. Different techniques were tested (monocortical, bicortical, and bicortical ass...

  19. Fluxes of water through aquaporin 9 weaken membrane-cytoskeleton anchorage and promote formation of membrane protrusions.

    Directory of Open Access Journals (Sweden)

    Thommie Karlsson

    Full Text Available All modes of cell migration require rapid rearrangements of cell shape, allowing the cell to navigate within narrow spaces in an extracellular matrix. Thus, a highly flexible membrane and a dynamic cytoskeleton are crucial for rapid cell migration. Cytoskeleton dynamics and tension also play instrumental roles in the formation of different specialized cell membrane protrusions, viz. lamellipodia, filopodia, and membrane blebs. The flux of water through membrane-anchored water channels, known as aquaporins (AQPs has recently been implicated in the regulation of cell motility, and here we provide novel evidence for the role of AQP9 in the development of various forms of membrane protrusion. Using multiple imaging techniques and cellular models we show that: (i AQP9 induced and accumulated in filopodia, (ii AQP9-associated filopodial extensions preceded actin polymerization, which was in turn crucial for their stability and dynamics, and (iii minute, local reductions in osmolarity immediately initiated small dynamic bleb-like protrusions, the size of which correlated with the reduction in osmotic pressure. Based on this, we present a model for AQP9-induced membrane protrusion, where the interplay of water fluxes through AQP9 and actin dynamics regulate the cellular protrusive and motile activity of cells.

  20. The Zonules Selectively Alter the Shape of the Lens During Accommodation Based on the Location of Their Anchorage Points

    Science.gov (United States)

    Nankivil, Derek; Maceo Heilman, Bianca; Durkee, Heather; Manns, Fabrice; Ehrmann, Klaus; Kelly, Shawn; Arrieta-Quintero, Esdras; Parel, Jean-Marie

    2015-01-01

    Purpose. To determine the role of anterior and posterior zonular tension on the optomechanical lens response during accommodation simulation. Methods. Ten eyes from nine hamadryas baboons (4.9 ± 0.7 years) and 20 eyes from 18 cynomolgus monkeys (5.4 ± 0.3 years) were dissected, leaving the lens, zonules, ciliary body, hyaloid membrane, anterior vitreous, and a segmented scleral rim intact. The lens preparation was mounted in a lens stretcher, and the outer scleral shell was displaced radially in a stepwise fashion. The load, lens, and ciliary body diameters, lens power, lens thickness, and the anterior and posterior radius of curvature were measured during stretching. The zonular fibers attached to either the posterior or anterior lens surface were then carefully transected and the experiment was repeated. Zonular transection was confirmed in four eyes via laser scanning confocal microscopy after immunostaining. The effect of zonular transection on the tissue response to stretching was quantified. Results. Without anterior zonules, 48% and 97% of the changes in anterior and posterior radii are retained. Without posterior zonules, 81% and 67% of the changes in anterior and posterior radii are retained. The changes in lens shape were reduced after transecting either the anterior or posterior zonules; however, both surfaces still changed shape. Conclusions. While either the anterior or posterior zonules alone are capable of changing the shape of both lens surfaces, the anterior zonules have a greater effect on the anterior lens surface, and the posterior zonules have a greater effect on the posterior lens surface. PMID:25698707

  1. Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

    Directory of Open Access Journals (Sweden)

    Jun Chen

    2000-05-01

    Full Text Available Survivin, a member of the inhibitor of apoptosis protein (IAP family, is detected in most common human cancers but not in adjacent normal cells. Previous studies suggest that survivin associates with the mitotic spindle and directly inhibits caspase activity. To further investigate the function of survivin, we used a survivin antisense (AS oligonucleotide to downregulate survivin expression in normal and cancer cells. We found that inhibition of survivin expression increased apoptosis and polyploidy while decreasing colony formation in soft agar. Immunohistochemistry showed that cells without survivin can initiate the cleavage furrow and contractile ring, but cannot complete cytokinesis, thus resulting in multinucleated cells. These findings indicate that survivin plays important roles in a late stage of cytokinesis, as well as in apoptosis.

  2. Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage

    DEFF Research Database (Denmark)

    Lydolph, Magnus C; Morgan-Fisher, Marie; Høye, Anette M;

    2009-01-01

    of endosomal vesicle recycling, but not inhibitors of protein kinase C or the small GTPase Rho. Our results demonstrated that although alpha9beta1 integrin can induce and localise to focal adhesions in a high activation state, its intermediate activity state normally supports cell adhesion consistent......Cell surface integrins are the primary receptors for cell migration on extracellular matrix, and exist in several activation states regulated in part by ectodomain conformation. The alpha9 integrin subunit, which pairs only with beta1, has specific roles in the immune system and may regulate cell...... migration. Melanoma cells express abundant alpha9beta1 integrin, and its role in cell migration was assessed. Ligands derived from Tenascin-C and ADAM12 supported alpha9beta1 integrin-mediated cell attachment and GTP-Rac dependent migration, but not focal adhesion formation. Manganese ions induced alpha9...

  3. Brief introduction to worldwide test types of anchorage%国内外锚杆试验类型简介

    Institute of Scientific and Technical Information of China (English)

    付文光

    2014-01-01

    There are three test types of ground anchor such as basic test, creep test and acceptance test in China, and performance test, proof test and extended creep test in US, and investigation test, suitability test and acceptance test in EU. In addition, there are some tests for some determinate aspects of anchor performance in US and EU such as lift-off test, oscillating load test, testing of corrosion protection, test for cyclic work load, etc. The demands for anchor tests in US code is relatively simpler while more strict and precise in EU code. The meaning and function of basic tests on anchor attract no enough attention in China. It should be more zetetic but not proof for testing and understanding the anchor performances more adequately.%国内锚杆试验类型分为基本试验、蠕变试验及验收试验3类,美国分为性能试验、验证试验及延长蠕变试验3类,欧洲分为探究试验、适应试验及验收试验3类,此外欧美还有提离试验、交变荷载试验、腐蚀防护完整性试验、确定波动荷载下最大工作荷载的试验等一些检测锚杆某些方面性能的试验。相对而言,美国标准对锚杆试验的要求简单一些,欧洲的更严格、更严谨一些。国内工程中,对锚杆基本试验的意义与作用尚重视不够,应把其作为探究性试验而非验证性试验,以便能够更为充分地测试及了解锚杆的性能。

  4. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines

    International Nuclear Information System (INIS)

    Infection with high-risk human papillomaviruses is causally linked to cervical carcinogenesis. However, most lesions caused by high-risk HPV infections do not progress to cancer. Host cell mutations contribute to malignant progression but the molecular nature of such mutations is unknown. Based on a previous study that reported an association between liver kinase B1 (LKB1) tumor suppressor loss and poor outcome in cervical cancer, we sought to determine the molecular basis for this observation. LKB1-negative cervical and lung cancer cells were reconstituted with wild type or kinase defective LKB1 mutants and we examined the importance of LKB1 catalytic activity in known LKB1-regulated processes including inhibition of cell proliferation and elevated resistance to energy stress. Our studies revealed marked differences in the biological activities of two kinase defective LKB1 mutants in the various cell lines. Thus, our results suggest that LKB1 may be a cell-type specific tumor suppressor. - Highlights: • LKB1 is a tumor suppressor that is linked to Peutz-Jeghers syndrome. • Peutz-Jeghers syndrome patients have a high incidence of cervical cancer. • Cervical cancer is caused by HPV infections. • This study investigates LKB1 tumor suppressor activity in cervical cancer

  5. Measurement of strain distribution in cortical bone around miniscrew implants used for orthodontic anchorage using digital speckle pattern interferometry

    Science.gov (United States)

    Kumar, Manoj; Agarwal, Rupali; Bhutani, Ravi; Shakher, Chandra

    2016-05-01

    An application of digital speckle pattern interferometry (DSPI) for the measurement of deformations and strain-field distributions developed in cortical bone around orthodontic miniscrew implants inserted into the human maxilla is presented. The purpose of this study is to measure and compare the strain distribution in cortical bone/miniscrew interface of human maxilla around miniscrew implants of different diameters, different implant lengths, and implants of different commercially available companies. The technique is also used to measure tilt/rotation of canine caused due to the application of retraction springs. The proposed technique has high sensitivity and enables the observation of deformation/strain distribution. In DSPI, two specklegrams are recorded corresponding to pre- and postloading of the retraction spring. The DSPI fringe pattern is observed by subtracting these two specklegrams. Optical phase was extracted using Riesz transform and the monogenic signal from a single DSPI fringe pattern. The obtained phase is used to calculate the parameters of interest such as displacement/deformation and strain/stress. The experiment was conducted on a dry human skull fulfilling the criteria of intact dental arches and all teeth present. Eight different miniscrew implants were loaded with an insertion angulation of 45 deg in the inter-radicular region of the maxillary second premolar and molar region. The loading of miniscrew implants was done with force level (150 gf) by nickel-titanium closed-coil springs (9 mm). The obtained results from DSPI reveal that implant diameter and implant length affect the displacement and strain distribution in cortical bone layer surrounding the miniscrew implant.

  6. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Mack, Hildegard I.D.; Munger, Karl, E-mail: kmunger@rics.bwh.harvard.edu

    2013-11-15

    Infection with high-risk human papillomaviruses is causally linked to cervical carcinogenesis. However, most lesions caused by high-risk HPV infections do not progress to cancer. Host cell mutations contribute to malignant progression but the molecular nature of such mutations is unknown. Based on a previous study that reported an association between liver kinase B1 (LKB1) tumor suppressor loss and poor outcome in cervical cancer, we sought to determine the molecular basis for this observation. LKB1-negative cervical and lung cancer cells were reconstituted with wild type or kinase defective LKB1 mutants and we examined the importance of LKB1 catalytic activity in known LKB1-regulated processes including inhibition of cell proliferation and elevated resistance to energy stress. Our studies revealed marked differences in the biological activities of two kinase defective LKB1 mutants in the various cell lines. Thus, our results suggest that LKB1 may be a cell-type specific tumor suppressor. - Highlights: • LKB1 is a tumor suppressor that is linked to Peutz-Jeghers syndrome. • Peutz-Jeghers syndrome patients have a high incidence of cervical cancer. • Cervical cancer is caused by HPV infections. • This study investigates LKB1 tumor suppressor activity in cervical cancer.

  7. Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea

    Science.gov (United States)

    Jin, Yecheng; Ren, Naixia; Li, Shiwei; Fu, Xiaolong; Sun, Xiaoyang; Men, Yuqin; Xu, Zhigang; Zhang, Jian; Xie, Yue; Xia, Ming; Gao, Jiangang

    2016-01-01

    Hair cells (HCs) are mechanosensors that play crucial roles in perceiving sound, acceleration, and fluid motion. The precise architecture of the auditory epithelium and its repair after HC loss is indispensable to the function of organ of Corti (OC). In this study, we showed that Brg1 was highly expressed in auditory HCs. Specific deletion of Brg1 in postnatal HCs resulted in rapid HC degeneration and profound deafness in mice. Further experiments showed that cell-intrinsic polarity of HCs was abolished, docking of outer hair cells (OHCs) by Deiter’s cells (DCs) failed, and scar formation in the reticular lamina was deficient. We demonstrated that Brg1 ablation disrupted the Gαi/Insc/LGN and aPKC asymmetric distributions, without overt effects on the core planer cell polarity (PCP) pathway. We also demonstrated that Brg1-deficient HCs underwent apoptosis, and that leakage in the reticular lamina caused by deficient scar formation shifted the mode of OHC death from apoptosis to necrosis. Together, these data demonstrated a requirement for Brg1 activity in HC development and suggested a role for Brg1 in the proper cellular structure formation of HCs. PMID:27255603

  8. Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

    Directory of Open Access Journals (Sweden)

    Martin F Dietrich

    Full Text Available BACKGROUND: The low-density lipoprotein (LDL receptor gene family is a highly conserved group of membrane receptors with diverse functions in developmental processes, lipoprotein trafficking, and cell signaling. The low-density lipoprotein (LDL receptor-related protein 1b (LRP1B was reported to be deleted in several types of human malignancies, including non-small cell lung cancer. Our group has previously reported that a distal extracellular truncation of murine Lrp1b that is predicted to secrete the entire intact extracellular domain (ECD is fully viable with no apparent phenotype. METHODS AND PRINCIPAL FINDINGS: Here, we have used a gene targeting approach to create two mouse lines carrying internally rearranged exons of Lrp1b that are predicted to truncate the protein closer to the N-terminus and to prevent normal trafficking through the secretary pathway. Both mutations result in early embryonic lethality, but, as expected from the restricted expression pattern of LRP1b in vivo, loss of Lrp1b does not cause cellular lethality as homozygous Lrp1b-deficient blastocysts can be propagated normally in culture. This is similar to findings for another LDL receptor family member, Lrp4. We provide in vitro evidence that Lrp4 undergoes regulated intramembraneous processing through metalloproteases and gamma-secretase cleavage. We further demonstrate negative regulation of the Wnt signaling pathway by the soluble extracellular domain. CONCLUSIONS AND SIGNIFICANCE: Our results underline a crucial role for Lrp1b in development. The expression in mice of truncated alleles of Lrp1b and Lrp4 with deletions of the transmembrane and intracellular domains leads to release of the extracellular domain into the extracellular space, which is sufficient to confer viability. In contrast, null mutations are embryonically (Lrp1b or perinatally (Lrp4 lethal. These findings suggest that the extracellular domains of both proteins may function as a scavenger for signaling ligands or signal modulators in the extracellular space, thereby preserving signaling thresholds that are critical for embryonic development, as well as for the clear, but poorly understood role of LRP1b in cancer.

  9. 76 FR 39386 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage...

    Science.gov (United States)

    2011-07-06

    ... vitulina), by Level B harassment, incidental to in-water pile driving were issued on July 15, 2009 (74 FR... monitoring team from the Alaska Pacific University (APU) to implement a NMFS-approved scientific monitoring... (ICRC, 2011). A summary of that report follows. The APU observers conducted scientific monitoring...

  10. 75 FR 38465 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage...

    Science.gov (United States)

    2010-07-02

    ... driving were issued on July 15, 2009 (74 FR 35136), and remain in effect until July 14, 2014. These... (APU) to implement a NMFS-approved scientific monitoring plan. The scientific marine mammal monitoring.... The APU observers conducted scientific monitoring from the Cairn Point Station on Elmendorf Air...

  11. 33 CFR 110.210 - San Diego Harbor, CA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false San Diego Harbor, CA. 110.210 Section 110.210 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.210 San Diego Harbor, CA. (a) The anchorage grounds. (1) Special anchorage for U.S. Government...

  12. 33 CFR 110.238 - Apra Harbor, Guam.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. 110.238 Section 110.238 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.238 Apra Harbor, Guam. (a) The anchorage grounds (Datum: WGS 84). (1) General Anchorage. The...

  13. 33 CFR 110.212 - Newport Bay Harbor, Calif.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.212 Newport Bay Harbor, Calif. (a) The anchorage... anchors or mooring in place and fixed mooring piles or stakes are prohibited. (3) Anchorage C-3. A... and other local harbor regulations for recreational and small craft of such size and alignment...

  14. 33 CFR 110.216 - Pacific Ocean at Santa Catalina Island, Calif.

    Science.gov (United States)

    2010-07-01

    ... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.216 Pacific Ocean at Santa...°19′16.7″ W. (b) The regulations. (1) The Descanso Bay anchorage is reserved for yachts and other.... Fixed mooring piles or stakes are prohibited. (2) The Isthmus Cove anchorage shall be available...

  15. 75 FR 54092 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-09-03

    ... Management Council's (Council) Scallop Plan Team will meet September 28th, 2010 at the Anchorage Hilton Hotel... be held at the Anchorage Hilton Hotel, 500 West 3rd Avenue, Anchorage, AK 99501. Council...

  16. 33 CFR 110.74 - Marco Island, Marco River, Fla.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74 Marco Island, Marco River, Fla. Beginning... place will be allowed. Fixed mooring piles or stakes are prohibited. All moorings shall be so...

  17. 33 CFR 110.128 - Columbia River at Portland, Oreg.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.128 Columbia River at Portland, Oreg. The waters of the Columbia River between Sand Island and Government Island, bounded on the west by pile...

  18. 33 CFR 110.50c - Mumford Cove, Groton, Conn.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.50c Mumford Cove, Groton, Conn. (a) Area No. 1... be allowed. Fixed mooring piles or stakes will be prohibited. The anchoring of vessels and placing...

  19. 33 CFR 110.58 - Cos Cob Harbor, Greenwich, Conn.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.58 Cos Cob Harbor, Greenwich, Conn. (a) Area A... or buoys for marking anchors will be allowed. Fixed mooring piles or stakes are prohibited....

  20. 33 CFR 110.127a - Lake Powell, Utah-Arizona.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.127a Lake Powell, Utah-Arizona. (a) Castel...″ W. Note: Fixed moorings, piles, or stakes are prohibited. Single and fore-and-aft temporary...

  1. 33 CFR 110.127b - Flaming Gorge Lake, Wyoming-Utah.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.127b Flaming Gorge Lake, Wyoming-Utah. (a... moorings, piles, or stakes are prohibited. Single and fore-and-aft temporary moorings will be allowed....

  2. 33 CFR 110.50d - Mystic Harbor, Noank, Conn.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.50d Mystic Harbor, Noank, Conn. (a) The area... or buoys for marking anchors will be allowed but fixed piles or stakes are prohibited. All...

  3. 33 CFR 110.50b - Mystic Harbor, Groton and Stonington, Conn.

    Science.gov (United States)

    2010-07-01

    ... SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.50b Mystic Harbor, Groton and... allowed. Fixed mooring piles or stakes are prohibited. All moorings shall be so placed that no...

  4. "Landslide at sunuapa 401 (hydrocarbon exploration well). Risk reduction by mitigation measures: drainage, piles barrier and anchorages system, shotcrete and reforestation, Chiapas, México".

    Science.gov (United States)

    Cuanalo, Oscar; Polanco, Gabriel; Rivera, Julio

    2013-04-01

    We report the case of a landslide of hydrocarbon exploration well "Sunuapa 401" located in Chiapas, Mexico. First were identified the determinants and triggers factors (morphology, geology, rain, seismic and volcanic activity, human activity, etc); second we assessed the threat, vulnerability and risk from geotechnical stability analysis (safety factor and critical failure surface); third, by using the methodology of valuation factors, stabilization processes were selected and designed, and finally they were built by Petróleos Mexicanos, in order to avoid a disaster (environmental, ecological and social). These construction processes included drainage elements, flattening and benching of slopes, piles barrier and anchors, shotcrete and reforestation.

  5. A role for Mfb1p in region-specific anchorage of high-functioning mitochondria and lifespan in Saccharomyces cerevisiae

    OpenAIRE

    Pernice, Wolfgang M.; Vevea, Jason D.; Pon, Liza A.

    2016-01-01

    Previous studies indicate that replicative lifespan in daughter cells of Sacchraromyces cerevisiae depends on the preferential inheritance of young, high-functioning mitochondria. We report here that mitochondria are functionally segregated even within single mother cells in S. cerevisiae. A high-functioning population of mitochondria accumulates at the tip of the mother cell distal to the bud. We find that the mitochondrial F-box protein (Mfb1p) localizes to mitochondria in the mother tip an...

  6. 微型种植体支抗正畸过程中的稳定性%Stability of mini-implant during orthodontic treatment as anchorage

    Institute of Scientific and Technical Information of China (English)

    石彦涛; 平燕; 单丽华; 宋建设; 邱志香

    2008-01-01

    背景:微型种植体作为绝对支抗应用于正畸治疗中存在的最大问题是稳定性.目的:应用微型种植体支抗内收上颌前牙,观察上颌前牙及第一磨牙位置的变化,评价微型种植体作为强支抗在正畸治疗过程中的稳定性.设计、时间及地点:对比观察实验.于2006-10/2007-12选择河北医科大学第二医院口腔正畸科门诊患者.对象:选取门诊就诊的双颌前突或上颌前突患者20例,男6例,女14例;年龄15-27岁,平均20.7岁.矫治设计拔除4颗第1 双尖牙或上颌第1及下颌第2双尖牙.方法:随机选择10例应用上颌后牙区微螺钉型种植体支抗内收前牙,微型钛钉直径为1.5 mm,长度为8 mm,由西安中邦钛生物制品有限公司提供.所有种植体由同一术者采取相同的手术方式植入.另10 例采用腭杆加口外弓的支抗方法.主要观察指标:治疗前及关闭拔牙间隙后拍摄X射线头颅侧位片,测量前牙内收情况、软组织变化及磨牙支抗的变化.结果:①微型钛钉种植体存拔牙间隙关闭的过程中保持了稳定,成功率89%.②种植体支抗治疗后上中切牙倾角及凸距的减少量明显多于非种植体强支抗治疗后的减少量.差异有显著性意义(P<0.01);种植体支抗组磨牙位移明显少于非种植体强支抗组.差异有显著性意义(P<0.01).结论:微型钛钉种植体作为稳定的骨件正畸支抗,可以实现理想的支抗控制效果.

  7. Mini-implant anchorage in orthodontic treatment related to molar problems%种植体支抗在磨牙矫治中临床应用

    Institute of Scientific and Technical Information of China (English)

    寻春雷; 曾祥龙

    2009-01-01

    目前对磨牙问题的关注和研究使得正畸医生对错牙争机制的认识和矫治设计的理念正在发生某些改变.而针对主要由磨牙问题形成的错牙争畸形进行的磨牙矫治,无论是在设计思想还是矫治手段上,都是一类棘手的难题.近年来,微型种植体支抗技术得到快速发展,有助于在解决这类难题时提供崭新的思路.本文概述种植支抗和磨牙矫治的结合带给正畸设计和治疗理念上的变化.

  8. Orthodontic clinical application of mini- implant anchorage%微小种植体支抗在正畸临床中的应用

    Institute of Scientific and Technical Information of China (English)

    刘鑫; 张云飞

    2009-01-01

    通过对利用微小种植体作为支抗来完成关闭拔牙间隙、推磨牙向远中、压低后牙、压低前牙、解决后牙锁、上颌单侧扩弓、协助导萌、直立或前移磨牙的正畸矫治的描述,介绍了常见的微小种植体支抗在正畸临床的应用方法,以期为正畸医生在临床正确使用微小种植体提供一定的帮助.

  9. 微小种植体支抗手术的护理配合%Nursing Cooperation of Mini-implant Surgery for Orthodontic Anchorage

    Institute of Scientific and Technical Information of China (English)

    张楠楠; 高妍

    2016-01-01

    对47例接受微小种植体支抗手术的患者进行术前、术中和术后护理,探讨微小种植体支抗手术的最佳护理配合措施。做好种植体支抗手术患者的护理配合,可避免伤口感染,促进伤口愈合,并可提高种植支抗手术的成功率。

  10. A Novel Rat Model of Orthodontic Tooth Movement Using Temporary Skeletal Anchorage Devices: 3D Finite Element Analysis and In Vivo Validation

    Science.gov (United States)

    Stevenson, Thomas; Doschak, Michael

    2014-01-01

    The aim of this animal study was to develop a model of orthodontic tooth movement using a microimplant as a TSAD in rodents. A finite element model of the TSAD in alveolar bone was built using μCT images of rat maxilla to determine the von Mises stresses and displacement in the alveolar bone surrounding the TSAD. For in vivo validation of the FE model, Sprague-Dawley rats (n = 25) were used and a Stryker 1.2 × 3 mm microimplant was inserted in the right maxilla and used to protract the right first permanent molar using a NiTi closed coil spring. Tooth movement measurements were taken at baseline, 4 and 8 weeks. At 8 weeks, animals were euthanized and tissues were analyzed by histology and EPMA. FE modeling showed maximum von Mises stress of 45 Mpa near the apex of TSAD but the average von Mises stress was under 25 Mpa. Appreciable tooth movement of 0.62 ± 0.04 mm at 4 weeks and 1.99 ± 0.14 mm at 8 weeks was obtained. Histological and EPMA results demonstrated no active bone remodeling around the TSAD at 8 weeks depicting good secondary stability. This study provided evidence that protracted tooth movement is achieved in small animals using TSADs. PMID:25295060

  11. Prestressed anchorage cable construction technique and unit price analysis%预应力锚索施工技术及单价分析

    Institute of Scientific and Technical Information of China (English)

    王家海

    2003-01-01

    预应力锚索技术是一种新加固土体技术,在铁路的高路堑边坡加固工程中得到越来越广泛的应用.笔者结合现场施工的实际经验,简要介绍了预应力锚索技术施工工序及单价分析.

  12. Brefeldin A Reduces Anchorage-Independent Survival, Cancer Stem Cell Potential and Migration of MDA-MB-231 Human Breast Cancer Cells

    Directory of Open Access Journals (Sweden)

    Chao-Neng Tseng

    2014-10-01

    Full Text Available Cancer stem cells (CSCs are a subset of cancer cells in tumors or established cancer cell lines that can initiate and sustain the growth of tumors in vivo. Cancer stem cells can be enriched in serum-free, suspended cultures that allow the formation of tumorspheres over several days to weeks. Brefeldin A (BFA is a mycotoxin that induces endoplasmic reticulum (ER stress in eukaryotic cells. We found that BFA, at sub-microgram per milliliter concentrations, preferentially induced cell death in MDA-MB-231 suspension cultures (EC50: 0.016 µg/mL compared to adhesion cultures. BFA also effectively inhibited clonogenic activity and the migration and matrix metalloproteinases-9 (MMP-9 activity of MDA-MB-231 cells. Western blotting analysis indicated that the effects of BFA may be mediated by the down-regulation of breast CSC marker CD44 and anti-apoptotic proteins Bcl-2 and Mcl-1, as well as the reversal of epithelial-mesenchymal transition. Furthermore, BFA also displayed selective cytotoxicity toward suspended MDA-MB-468 cells, and suppressed tumorsphere formation in T47D and MDA-MB-453 cells, suggesting that BFA may be effective against breast cancer cells of various phenotypes.

  13. Application of anchorages in treatment of quality defects of aqueducts%植筋技术在渡槽质量事故处理中的应用

    Institute of Scientific and Technical Information of China (English)

    方业源

    2010-01-01

    五化灌区塘柳渡槽在施工不慎发生槽壁钢筋严重偏移的质量事故,在受到施工工期严格限制的情况下采用植筋技术,弥补了施工缺陷.本文介绍了该质量事故的处理方案、植筋的具体施工工序和需要注意的一些问题,可为工程技术人员处理类似质量事故提供参考.

  14. Transformation of primary human embryonic kidney cells to anchorage independence by a combination of BK virus DNA and the Harvey-ras oncogene

    International Nuclear Information System (INIS)

    Primary human embryonic kidney (HEK) cells were transformed by a focus assay with BK virus (BKV) DNA molecularly cloned at its unique EcoRI site. Both viral DNA sequences and viral tumor antigens were present and expressed in all the foci that the authors examined. However, cells isolated from foci were incapable of growth in soft agar. They then examined the transformation of HEK cells after their transfection with a combination of BKV DNA and either the normal or the activated form of the human Ha-ras oncogene (EJ c-Ha-ras-1). Only the cells transfected with a combination of BKV DNA and the activated form of Ha-ras DNAs were present in the transformed colonies. BKV tumor antigens and the Ha-ras p21 protein were also expressed

  15. 33 CFR 110.208 - Buffalo Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo Harbor, N.Y. 110.208 Section 110.208 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.208 Buffalo Harbor, N.Y. (a) The anchorage...

  16. 33 CFR 110.150 - Block Island Sound, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Block Island Sound, N.Y. 110.150 Section 110.150 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.150 Block Island Sound, N.Y. (a) The anchorage ground. A...

  17. 33 CFR 110.142 - Nantucket Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Nantucket Harbor, Mass. 110.142 Section 110.142 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.142 Nantucket Harbor, Mass. (a) The anchorage grounds. In...

  18. 33 CFR 110.131 - Sheepscot River in the vicinity of Edgecomb, Maine.

    Science.gov (United States)

    2010-07-01

    ... OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.131 Sheepscot River in... the point of beginning. DATUM: NAD 83 (b) Regulations. (1) This anchorage is reserved for vessels of... through October. (3) Vessels are limited to a maximum stay of 1 week. (4) Fixed moorings, piles or...

  19. 33 CFR 110.145 - Narragansett Bay, R.I.

    Science.gov (United States)

    2010-07-01

    ... will be allowed in this area. Fixed mooring piles or stakes will not be allowed. (d) The regulations... ANCHORAGE REGULATIONS Anchorage Grounds § 110.145 Narragansett Bay, R.I. (a) East Passage—(1) Anchorage A... area. Fixed mooring piles or stakes will not be allowed. (2) Anchorage B. Off the west shore...

  20. 33 CFR 110.196 - Sabine Pass Channel, Sabine Pass, Tex.

    Science.gov (United States)

    2010-07-01

    ... SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.196 Sabine Pass Channel, Sabine Pass, Tex...) The regulations. (1) The anchorage area is for the temporary use of vessels of all types, but... paragraph (b)(3) of this section. (6) Fixed moorings, piles or stakes, and floats or buoys for...

  1. 33 CFR 110.148 - Johnsons River at Bridgeport, Conn.

    Science.gov (United States)

    2010-07-01

    ... SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.148 Johnsons River at Bridgeport, Conn... beginning. (b) The regulations. The anchorage is for use by commercial and pleasure craft. Temporary floats... temporary anchors or mooring piles are under the jurisdiction of the local harbor master. Fixed...

  2. 33 CFR 110.205 - Chicago Harbor, Ill.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Anchorage Grounds § 110.205 Chicago Harbor, Ill. (a) The anchorage grounds—(1... beginning. (b) The rules and regulations. (1) Except in cases of emergency, no vessel may be anchored in... making moorings or anchors in place in anchorages A and B. No person may place fixed moorings piles...

  3. 33 CFR 110.132 - Rockland Harbor, Maine.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Anchorage Grounds § 110.132 Rockland Harbor, Maine. (a) The anchorage grounds—(1...; and thence 169°, 900 yards, to the point of beginning. (b) The regulations. (1) Anchorages A and B are... feet in length. Fixed moorings, piles or stakes are prohibited. (2) A distance of approximately...

  4. 33 CFR 110.130 - Bar Harbor, Maine.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Anchorage Grounds § 110.130 Bar Harbor, Maine. (a) Anchorage grounds. (1) Anchorage “A...″ N 068°11′41″ W; thence to 44°24′02″ N 068°13′03″ W; returning to start. (b) Regulations. (1... buoys for marking anchors will be allowed in all anchorage areas. (4) Fixed moorings, piles or...

  5. 33 CFR 110.90 - San Diego Harbor, Calif.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.90 San Diego Harbor, Calif. (a) Area A-1. In North San... District. Temporary floats or buoys for marking anchors are allowed. Fixed moorings, piles or stakes...

  6. 33 CFR 110.50 - Stonington Harbor, Conn.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.50 Stonington Harbor, Conn. (a) Area No. 1. Beginning at... mooring stake or pile is prohibited. The General Statutes of the State of Connecticut authorizes...

  7. 33 CFR 110.127c - Trinidad Bay, Calif.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.127c Trinidad Bay, Calif. The waters of Trinidad Bay... floats and buoys for anchoring will be allowed in the area. Fixed moorings, piles or stakes...

  8. 33 CFR 110.59 - Eastern Long Island, NY.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.59 Eastern Long Island, NY. (a) Huntington Harbor... a vessel at anchor may be used. Fixed mooring piles or stakes are prohibited. (d) Cold Spring...

  9. Rock bolt mechanical analysis and its application to engineering

    Institute of Scientific and Technical Information of China (English)

    GUO Ling-yun; XIAO Ming; XIAO Ying-chun

    2008-01-01

    Combined with the 3D FEM, end-anchored anchorage bolts were simulated by implicit anchorage bolt element. Implicit anchorage bolt elements hide in the elements of rock mass and extremely simplify the element subdivision. The calculated value of an-chorage bolt stress is larger than the measured one for the most time. we further analyzed the reciprocity of anchorage bolt and rock mass, and then deduced the analytical equa-tions of anchorage bolt stress and rock mass deformation under elasto-plastic state. The results indicate that it is essential to revise the anchorage bolts stress by using the formu-las deduced when rock mass is softened or significantly deformed. Finally, a case study indicates that the calculated results agree with those measured. Some helpful methods are offerd for more accurate simulation of the support effect and anchorage bolts real stress state.

  10. 33 CFR 110.71 - Jacobs Nose Cove, Elk River, Md.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Jacobs Nose Cove, Elk River, Md... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.71 Jacobs Nose Cove, Elk River, Md. The water area of Jacobs Nose Cove, on the west side of the mouth of Elk River, Maryland, comprising the...

  11. 33 CFR 110.111 - Marina del Rey Harbor, Calif.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marina del Rey Harbor, Calif. 110.111 Section 110.111 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.111 Marina del Rey Harbor, Calif. An area...

  12. 33 CFR 110.53 - Niantic, Conn.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Niantic, Conn. 110.53 Section 110.53 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.53 Niantic, Conn. Beginning on the shoreline at latitude...

  13. 33 CFR 110.229 - Straits of Juan de Fuca, Wash.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Straits of Juan de Fuca, Wash. 110.229 Section 110.229 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.229 Straits of Juan de Fuca, Wash. (a)...

  14. 33 CFR 110.230 - Puget Sound Area, Wash.

    Science.gov (United States)

    2010-07-01

    ... citations affecting § 110.230, see the List of CFR Sections Affected, which appears in the Finding Aids... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Puget Sound Area, Wash. 110.230... ANCHORAGE REGULATIONS Anchorage Grounds § 110.230 Puget Sound Area, Wash. (a) The anchorage...

  15. 33 CFR 110.87 - Henderson Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Henderson Harbor, N.Y. 110.87 Section 110.87 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.87 Henderson Harbor, N.Y. (a) Area A. The area in...

  16. 33 CFR 110.84b - Buffalo, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo, N.Y. 110.84b Section 110.84b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.84b Buffalo, N.Y. The area within the Port of Buffalo known as...

  17. 33 CFR 110.85 - Niagara River, Youngstown, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Niagara River, Youngstown, N.Y. 110.85 Section 110.85 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.85 Niagara River, Youngstown, N.Y. (a) Area...

  18. 33 CFR 110.170 - Lockwoods Folly Inlet, N.C.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lockwoods Folly Inlet, N.C. 110.170 Section 110.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.170 Lockwoods Folly Inlet, N.C. (a)...

  19. 33 CFR 110.168 - Hampton Roads, Virginia and adjacent waters (Datum: NAD 83).

    Science.gov (United States)

    2010-07-01

    ... explosives, as defined in 49 CFR 173.50. Dangerous cargo means “certain dangerous cargo” as defined in § 160... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hampton Roads, Virginia and..., DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.168 Hampton...

  20. 33 CFR 110.27 - Lynn Harbor in Broad Sound, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lynn Harbor in Broad Sound, Mass. 110.27 Section 110.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.27 Lynn Harbor in Broad Sound, Mass. North...

  1. 33 CFR 110.38 - Edgartown Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Edgartown Harbor, Mass. 110.38 Section 110.38 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.38 Edgartown Harbor, Mass. An area in the inner...

  2. 33 CFR 110.37 - Sesuit Harbor, Dennis, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sesuit Harbor, Dennis, Mass. 110.37 Section 110.37 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.37 Sesuit Harbor, Dennis, Mass. All the...

  3. 33 CFR 110.29 - Boston Inner Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Boston Inner Harbor, Mass. 110.29 Section 110.29 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.29 Boston Inner Harbor, Mass. (a) Vicinity of...

  4. 33 CFR 110.45 - Onset Bay, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Onset Bay, Mass. 110.45 Section 110.45 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.45 Onset Bay, Mass. Northerly of a line extending...

  5. 33 CFR 110.32 - Hingham Harbor, Hingham, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hingham Harbor, Hingham, Mass. 110.32 Section 110.32 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.32 Hingham Harbor, Hingham, Mass. (a) Area...

  6. 33 CFR 110.186 - Port Everglades, Florida.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Port Everglades, Florida. 110.186... ANCHORAGE REGULATIONS Anchorage Grounds § 110.186 Port Everglades, Florida. (a) The anchorage grounds. The... entrance to Port Everglades, is an area bounded by a line connecting points with the following...

  7. 33 CFR 110.185 - Atlantic Ocean, off the Port of Palm Beach, FL.

    Science.gov (United States)

    2010-07-01

    ... Palm Beach, FL. 110.185 Section 110.185 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... of Palm Beach, FL. (a) The anchorage grounds. (1) Anchorage A. The waters lying within an area... Palm Beach, shall only anchor within the anchorage areas hereby defined and established, except...

  8. 33 CFR 110.74b - Apollo Beach, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a...

  9. 33 CFR 110.73b - Indian River at Vero Beach, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Indian River at Vero Beach, Fla... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73b Indian River at Vero Beach, Fla. (a) Area A. Beginning at a point located on the eastern shore of Fritz Is. at latitude 27°39′32.5″...

  10. 33 CFR 110.129a - Apra Harbor, Guam. (Datum: WGS 84)

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. (Datum: WGS 84) 110.129a Section 110.129a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.129a Apra Harbor, Guam. (Datum: WGS 84)...

  11. 33 CFR 110.157 - Delaware Bay and River.

    Science.gov (United States)

    2010-07-01

    ... 48°, 2,000 yards; and thence 138°, 8,000 yards, to the point of beginning. (3) Anchorage 2 northwest... in this anchorage in such manner as to interfere unreasonably with the passage of other vessels to... shift position. (17) Anchorage 16 between Port Richmond and Five Mile Point. On the northwest side...

  12. 33 CFR 110.255 - Ponce Harbor, P.R.

    Science.gov (United States)

    2010-07-01

    ...) Floats for marking anchors in place will be allowed; stakes or mooring piles are prohibited. 33 CFR Ch. I... ANCHORAGE REGULATIONS Anchorage Grounds § 110.255 Ponce Harbor, P.R. (a) Small-craft anchorage. On the...′ true, 1,800 feet; thence 195° true, 900 feet to the point of beginning. (b) The regulations. (1)...

  13. 33 CFR 110.127 - Lake Mohave and Lake Mead, Nevada and Arizona.

    Science.gov (United States)

    2010-07-01

    ... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.127 Lake Mohave and Lake...′50″ W. “c” 36°05′00″ N. 114°06′13″ W. Note: Fixed moorings, piles, or stakes are prohibited....

  14. 33 CFR 110.60 - Captain of the Port, New York.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.60 Captain of the Port, New York. (a) Western...): Temporary floats or buoys for marking anchors in place are allowed. Fixed mooring piles or stakes are... recreational craft on a seasonal or transient basis. These regulations do not prohibit the placement...

  15. 33 CFR 110.197 - Galveston Harbor, Bolivar Roads Channel, Texas.

    Science.gov (United States)

    2010-07-01

    ... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.197 Galveston Harbor, Bolivar.... 29°21′14.5″ N 94°45′49.0″ W. and thence to the point of beginning. (b) The regulations. (1) The... provisions in paragraph (b)(5) of this section. (8) Fixed moorings, piles or stakes, and floats or buoys...

  16. 33 CFR 110.55 - Connecticut River, Conn.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.55 Connecticut River, Conn. (a) West of Calves Island at... be allowed. Fixed mooring piles or stakes are prohibited. The anchoring of vessels and the placing of... mooring piles or stakes are prohibited. (d) Upper Bay—(1) Anchorage No. 20-A. (i) All waters bound by...

  17. Experimental Study on Anchorage Capacity of the Self-tapping Screws in Glulam%胶合木自攻螺钉拉拔锚固性能试验研究

    Institute of Scientific and Technical Information of China (English)

    倪鸣; 陆伟东; 路奎; 李强

    2015-01-01

    进行了不同锚固长度自攻螺钉拉拔强度的试验.研究了自攻螺钉拉拔的破坏形态,不同锚固长度以及自攻螺钉直径对拉拔强度的影响.试验结果表明:绝大多数试件发生木材的剪切破坏和自攻螺钉屈服破坏,个别试件发生劈裂破坏.自攻螺钉连接的拉拔承载力随锚固长度的增加而增大,当锚固长细比达到16时,试件发生自攻螺钉屈服破坏,属延性破坏;弦向锚固试件极限拉拔荷载均大于径向锚固试件.

  18. An archaeological site survey and inventory for the Aleutian Islands National Wildlife Refuge, Alaska 1972: A report submitted to the Wilderness Studies Branch, U.S. Fish and Wildlife Service, Anchorage, Alaska

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a 1972 voyage in the Aleutian archipelago to locate prehistoric and historic archeological sites. The report centers on the problems...

  19. Three-dimensional finite element analysis on mini-implants for orthodontic anchorage%正畸微种植体支抗的三维有限元研究进展

    Institute of Scientific and Technical Information of China (English)

    于海璐; 蔡兴伟; 李涛

    2016-01-01

    近年来,微种植体支抗在口腔正畸临床实践中的应用逐渐增多.与传统支抗相比,微种植体支抗体积较小且相对价格低廉、操作简便,能够解决更多疑难病例,但却仍然存在一定的失败率.为了进一步提高其稳定性,本文对国内外学者关于微种植体结构设计、骨质量、植体材料、正畸力载荷以及植入角度的有限元研究进行综述,进一步明确这些因素对于微种植体稳定性的影响,为微种植体支抗能够更加高效的应用于临床提供依据.

  20. Orthodontic treatment for gum-smile with mini-implant anchorage by maxillary anterior teeth intrusion%应用微种植体支抗压低上前牙改善露龈笑的临床研究

    Institute of Scientific and Technical Information of China (English)

    刘名燕; 任娟; 周斌; 冯云霞

    2014-01-01

    目的 探讨上颌前牙区微种植体支抗压低上前牙改善露龈笑的临床疗效.方法 选择露龈笑伴深覆殆患者15例,平均年龄(19.7±5.4)岁,在位于12,22近中根尖处颌骨内各植入1颗微种植钉,在方丝12,22近中置游离拉钩,向微种植钉做弹性牵引,每侧加力0.6N,平均加力压低的时间为(6.2±1.6)个月.测量矫治前后X线头颅侧位片的相关软硬组织指标,使用SPSS 13.0软件进行统计分析.结果 前牙垂直压低的量及切牙牙冠长度明显减少(P<0.01),磨牙伸长量不显著.前牙的覆殆与覆盖均矫治达到正常范围.结论 微种植体做支抗压低上前牙、纠正深覆黯效果理想,能有效改善露龈笑.

  1. 微型种植体支抗在青少年口腔正畸治疗中的效果及安全性%Efficacy and Safety of Mini Implant Anchorage in Orthodontic Treatment of Adolescents

    Institute of Scientific and Technical Information of China (English)

    孙洁; 邓立兰; 凌燕; 魏永亮; 史聪翀

    2016-01-01

    目的:研究微型种植体支抗治疗青少年口腔正畸的疗效及安全性.方法:选择2013年5月-2015年5月在我院接受治疗的80例青少年口腔正畸患者,随机分为试验组和对照组.试验组给予微型种植体支抗治疗,对照组给予传统正畸治疗.观察并比较两组患者的临床疗效、不良反应及头影测量结果.结果:试验组患者的上、中切牙倾角差、上中切牙凸距差、磨牙移位的改善情况均明显高于对照组,差异有统计学意义(P<0.05);与治疗前比较,两组患者治疗后U1-L1、U1-SN、L1-MP、U1-NA、L1-NB、SNA、SNB及ANB差值均有统计学意义(P<0.05);试验组U1-L1、SNB显著大于对照组,其他指标均显著小于对照组,差异具有统计学意义(P<0.05);试验组患者不良反应的发生率明显低于对照组,差异具有统计学意义(P<0.05).结论:与传统支抗方法相比,微型种植体支抗用于青少年口腔正畸治疗具有操作简便、疗效显著、安全性较高等优点,适合在临床推广使用.

  2. Effect of Orthodontic Mini-implant Anchorage on Masticatory Function Of Malocclusion Patients%微型种植钉支抗法正畸对错(牙合)畸形患者咀嚼功能的影响

    Institute of Scientific and Technical Information of China (English)

    纪芳; 刘宝君; 陶疆

    2009-01-01

    [目的]研究微型种植钉支抗正畸矫治错(牙合)畸形患者手术前后咀嚼功能的变化.[方法]选择安氏Ⅱ类伴上颌前突患者24例,用微型种植钉加强支抗,分别测定治疗前后的吞咽起始时间以及治疗前后的咀嚼效率.[结果]①24例中21例微型种植钉成功作为加强支抗完成治疗,磨牙前移轻微,切牙后移明显,成功率为87.5%;②矫治前后吞咽开始时间的减少值和咀嚼效率的改善值相比均有统计学意叉(P<0.05).[结论]微型种植钉支抗法正畸成功率高,能够有效改善错(牙合)畸形患者的咀嚼功能.

  3. Clinical application of mini-screw implant anchorage for anterior teeth retraction orthodontic treatment%微型种植体支抗在内收前牙正畸治疗中的临床应用

    Institute of Scientific and Technical Information of China (English)

    安志良; 胡玉柱; 詹颖; 张朝晖; 刘志利

    2008-01-01

    目的 评价微螺钉种植体在正畸治疗中作为支抗内收前牙的有效性.方法 选择双颌前突和上颌前突的患者共19例,应用上、下颌后牙区微螺钉种植体作为支抗内收前牙.在治疗前后拍摄头颅定位侧位片,以SN为基准重叠治疗前、后头影测量描记图,观察第一磨牙的位置改变.治疗结束后观察患者前牙覆(牙合)覆盖关系和Ⅱ类磨牙关系的改变,以及面型凸度的改善程度.结果 19例患者中16例患者应用微螺钉种植体支抗顺利完成正畸治疗,均建立了正常的前牙覆(牙合)覆盖关系,成功纠正了Ⅱ类磨牙关系,面型凸度明显改善,第一磨牙位置稳定.结论 国产微螺钉种植体支抗与传统的强支抗方式相比,确保磨牙支抗不丧失的能力更强,几乎达到绝对支抗的能力,可以实现理想的支抗控制.

  4. Nursing experience on insertion of self-tapping mini-implant for orthodontic anchorage%自攻式微种植支抗钉植入术护理体会

    Institute of Scientific and Technical Information of China (English)

    林洁; 赵佛容

    2012-01-01

    目的 探讨自攻式微种植钉植入手术的护理要点.方法 150例需要植入微种植支抗钉病例,于齿槽骨或颌骨内植入自攻式微种植钉.在手术前进行心理护理和用物准备;术中配合医生操作,安抚患者;术后对患者进行饮食、口腔卫生等指导.结果 150例患者共植入322颗自攻式微种植钉,成功304颗,失败18颗,成功率94.4%.结论 正确的医护配合及术前术后的卫生宣教,既能减少感染的发生,也助于提高微种植支抗钉植入手术的成功率.

  5. Clinical outcome evaluation of midpalatal mini-implant anchorage system in orthodontic treatment%腭中部微种植钉支抗系统的临床效果评价

    Institute of Scientific and Technical Information of China (English)

    潘一春; 赵健慧

    2014-01-01

    目的:初步探讨腭中部微种植钉支抗系统在固定矫治中的支抗效果,为正畸临床支抗的选择提供参考.方法:选择骨性Ⅰ、Ⅱ类需上颌强支抗的青少年正畸患者14例作为研究对象,均采用双颌固定矫治器进行正畸治疗,在上颌减数两颗第一双尖牙并在腭中线旁、第一磨牙水平植入微种植钉一颗.以0.019 inch×0.022 inch(1inch =2.54 cm)的不锈钢方丝横腭杆固定连接微种植钉和双侧上颌第一磨牙,组成一个腭中部微种植钉支抗系统进行正畸力的负载,下牙列不纳入研究.植入微种植钉时(T0)、上颌间隙关闭或基本关闭时(T1)分别拍摄头颅侧位片进行头影测量描图.分别采用SN-7平面及PP平面作为参考平面,对微种植钉以及上颌第一磨牙在T0、T1的位置差异进行头影测量分析.采用配对t检验进行统计学分析.结果:腭中部微种植钉植入后的临床成功率为73.9%.14例进行测量分析的病例中,微种植系统负载正畸力后仍保持稳固,双侧第一磨牙没有发生明显的近中移动.微种植钉以及上颌第一磨牙的位置变化在两组间的差异没有统计学意义.结论:本研究中设计的腭中部微种植支抗系统具有较好的稳定性,在正畸治疗中能够起到强支抗的作用,可作为一种正畸强支抗的可选方案在临床中应用.

  6. 正畸微种植体支抗功能期的护理%Postoperative nursing of patients accepting mini-implants for orthodontic anchorage in functional period

    Institute of Scientific and Technical Information of China (English)

    李珩; 张安翔; 雷逸灵

    2009-01-01

    @@ 近年来,种植支抗在正畸临床中正广泛推广应用[1].与传统支抗手段相比,微种植体支抗减少了病人的不适感,可实现对支抗的有效控制,应用安全、隐蔽、疗程短、植入方法简单和价格较低,在我国已迅速普及开展[2,3].

  7. Molecular mechanisms of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced inverted U-shaped dose responsiveness in anchorage independent growth and cell proliferation of human breast epithelial cells with stem cell characteristics

    International Nuclear Information System (INIS)

    Although 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has a variety of carcinogenic and noncarcinogenic effects in experimental animals, its role in human carcinogenicity remain controversial. A simian virus 40-immortalized cell line from normal human breast epithelial cells with stem cells and luminal characteristics (M13SV1) was used to study whether TCDD can induce AIG positive colony formation and cause increased cell numbers in a inverted U-shaped dose-response manner. TCDD activated Akt, ERK2, and increased the expression of CYP1A1, PAI-2, IL-lb mRNA, and ERK2 protein levels. TCDD was able to increased phosphorylation and expression of ERK2 in same dose-response manner as AIG positive colony formation. Thus, TCDD induced tumorigenicity in M13SV1, possibly through the phosphorylation of ERK2 and/or Akt. Further, cDNA microarray with 7448 sequence-verified clones was used to profile various gene expression patterns after treatment of TCDD. Three clear patterns could be delineated: genes that were dose-dependently up-regulated, genes expressed in either U-shape and/or inverted U-shape. The fact that these genes are intrinsically related to breast epithelial cell proliferation and survival clearly suggests that they may be involved in the TCDD-induced breast tumorigenesis

  8. 底板设置锚筋的圆形水泵房内力分析研究和实践%Inner Force Analytic Research and Practice of the Circular Pump House to Install Anchorage on Motherboard

    Institute of Scientific and Technical Information of China (English)

    陈惠明

    2003-01-01

    在岩基和水深较大的位置修筑水泵房时,在底板设置锚筋,对泵房抗浮、改善泵房内力分布,利用自然条件降低工程造价,起到较好的作用.对底板设置锚筋的圆形水泵房进行内力分析研究,并在来宾电厂水泵房中应用,取得很好的效果.

  9. Preliminary Geologic Map of the Cook Inlet Region, Alaska-Including Parts of the Talkeetna, Talkeetna Mountains, Tyonek, Anchorage, Lake Clark, Kenai, Seward, Iliamna, Seldovia, Mount Katmai, and Afognak 1:250,000-scale Quadrangles

    Science.gov (United States)

    Geologic map compiled by Wilson, Frederic H.; Hults, Chad P.; Schmoll, Henry R.; Haeussler, Peter J.; Schmidt, Jeanine M.; Yehle, Lynn A.; Digital files prepared by Wilson, Frederic H.; Labay, Keith A.; Shew, Nora

    2009-01-01

    The growth in the use of Geographic Information Systems (GIS) has highlighted the need for digital geologic maps that have been attributed with information about age and lithology. Such maps can be conveniently used to generate derivative maps for manifold special purposes such as mineral-resource assessment, metallogenic studies, tectonic studies, and environmental research. This report is part of a series of integrated geologic map databases that cover the entire United States. Three national-scale geologic maps that portray most or all of the United States already exist; for the conterminous U.S., King and Beikman (1974a,b) compiled a map at a scale of 1:2,500,000, Beikman (1980) compiled a map for Alaska at 1:2,500,000 scale, and for the entire U.S., Reed and others (2005a,b) compiled a map at a scale of 1:5,000,000. A digital version of the King and Beikman map was published by Schruben and others (1994). Reed and Bush (2004) produced a digital version of the Reed and others (2005a) map for the conterminous U.S. The present series of maps is intended to provide the next step in increased detail. State geologic maps that range in scale from 1:100,000 to 1:1,000,000 are available for most of the country, and digital versions of these state maps are the basis of this product. The digital geologic maps presented here are in a standardized format as ARC/INFO export files and as ArcView shape files. The files named __geol contain geologic polygons and line (contact) attributes; files named __fold contain fold axes; files named __lin contain lineaments; and files named __dike contain dikes as lines. Data tables that relate the map units to detailed lithologic and age information accompany these GIS files. The map is delivered as a set 1:250,000-scale quadrangle files. To the best of our ability, these quadrangle files are edge-matched with respect to geology. When the maps are merged, the combined attribute tables can be used directly with the merged maps to make derivative maps.

  10. 大直径螺柱焊在660kW风电地锚生产中的应用%Application of the large diameter stud welding in production of 660 kW windturbine anchorage

    Institute of Scientific and Technical Information of China (English)

    刘志颖; 赵宁; 曲俊霞

    2003-01-01

    通过螺柱焊技术在660 kW风力发电机组焊接结构件中的应用,对螺柱焊接的工艺焊接性和使用焊接性进行了探讨和论证.在实际生产过程中采集了大量试样进行加工试验.结果表明:螺柱焊技术在风电地锚生产应用中的加工适应性是良好的,能够获得优质的焊接接头,两种不同性质钢材的螺柱焊接头在产品设计要求的低温条件下可靠运行.

  11. GFRP锚杆结构预应力锁定装置研制与现场试验%Development of load anchorage device for pre-stress GFRP soil nail reinforcement element in slopes and field tests

    Institute of Scientific and Technical Information of China (English)

    刘龙; 李国维; 贺冠军; 余亮; 刘学

    2015-01-01

    The fiber reinforced polymer (FRP) bars have the behavior of strong corrosion resistance, high tensile strength and small elastic modulus, and can be used to replace steel bars, which undergo wearing due to rusting in slope reinforcement. The pre-stress FRP bars are reasonable, but the bars have low shear strength and cannot be pre-stressed using the traditional rigid clamp, lest they are crashed to failure. An end anchoring pre-stress locking device is designed for pre-stress application and retention in the FRP bars. Field tests are conducted to verify the stability of the device. The test results show that the device is practically feasible and convenient, and it can apply and retain pre-stress in basalt-glass fiber reinforced polymer (B-GFRP) bars well. Exposure to external factors such as heavy rains and blasting results in the loss of pre-stress. The pre-stress loss is caused by degeneration of the bonding resulting from external factors, but not by the invalidation of the device. The pre-stress retention by the device in the B-GFRP bars is 5%~35%, which conforms to the control criterion for the pre-stress loss of the steel pre-stressed soil nail reinforcement.%纤维增强聚合物(FRP)筋耐腐蚀,抗拉强度高,弹性模量小,用于边坡加固锚杆结构是解决钢筋锚杆结构耐久性问题的途径之一,预应力FRP锚杆结构是合理型式。FRP筋抗剪强度低,钢筋锚杆施加预应力采用的刚性夹具不能用于FRP锚杆。基于端部封闭的钢套管充填膨胀剂锚固FRP筋法,设计了FRP锚杆预应力施加及锚索装置,并进行了现场试验。试验结果表明:预应力锁定装置的原理可行,结构合理,使用方便,能较好地完成玄武–玻璃纤维增强聚合物(B-GFRP)锚杆的预应力施加和锁定,经历外部环境变化检验,降雨、震动等环境影响产生的预应力损失均缘于杆体界面的黏结蜕化,没有发生锁定装置失效导致荷载明显损失的现象。B-GFRP锚杆的预应力损失百分率在5%~35%间,达到了精轧螺纹钢锚杆预应力损失的控制标准。

  12. 锚碇沉箱基础与升浆基床摩擦性能研究%Research on friction property between anchorage caisson foundation and grouting bed

    Institute of Scientific and Technical Information of China (English)

    耿铁锁; 陈亮; 张哲

    2015-01-01

    According to the first domestic offshore suspension bridge using caisson foundation,the friction property between prepacked aggregate riprap grouting bed and concrete under water,the friction coefficients between gravel bed and concrete structure are mainly studied.Firstly,the friction coefficients between gravel bed and concrete structure are obtained by laboratory and field experiments,and then,the friction property between prepacked aggregate riprap grouting bed and concrete structure under water is acquired by the numerical analysis method.The experimental results show that the friction coefficients between the common gravel bed and the concrete caisson are in the range of 0.5-0.6,which meets the corresponding code,and the friction coefficient between the prepacked aggregate riprap grouting bed and the concrete caisson is within 0.7-0.8,or even 0.9 considering the film cohesive force of concrete.%针对国内首个采用沉箱基础的海上悬索桥,主要对水下预填骨料抛石升浆基床与混凝土之间的摩擦性能,以及碎石基床与混凝土结构的摩擦因数展开研究.首先通过室内和现场实验得到碎石基床与混凝土结构的摩擦因数,在此基础上采用数值分析方法得到水下预填骨料抛石升浆基床与混凝土结构之间的摩擦性能.结果表明,普通碎石基床与混凝土沉箱之间的摩擦因数在设计规范规定的0.5~0.6内,而预填骨料抛石升浆基床与混凝土沉箱之间的摩擦因数为0.7~0.8,如考虑混凝土之间的黏结力膜作用,摩擦因数可达0.9.

  13. Coated cables - evaluation of the behaviour towards atmospheric pulses for different configurations with anchorage/pin insulator; Cabos cobertos - a avaliacao do comportamento frente a impulsos atmosfericos para diferentes configuracoes com amarracao/isolador de pino

    Energy Technology Data Exchange (ETDEWEB)

    Tatizawa, Hedio; Oliveira, Joao Jose dos Santos; Marchetti, Jose Flavio Salles; Almeida, Geraldo R. de; Piazza, Elena Gloria B.E.; Pinheiro, Walter [Centro de Excelencia em Distribuicao de Energia Eletrica, Sao Paulo, SP (Brazil)

    1994-12-31

    This work aims to presents the studies developed by the Center of Electric Power Distribution Excellence in what concerns the performance of protected electric power transmission lines towards over tensions caused by atmospheric phenomena. The utilization of coated cables in overhead primary distribution networks is an alternative which enables the obtention of solutions for the limitations inherent of naked conductors networks towards environment interferences and network performance as well as safety improvement. The methodology and results are presented 22 refs., 3 figs., 5 tabs.

  14. 正畸微种植体支抗即刻加载的稳定性研究%Histological study on immediate loading of microimplant as orthodontic anchorage in dog

    Institute of Scientific and Technical Information of China (English)

    许衍; 曾科; 景熙文; 王林; 王震东

    2008-01-01

    目的 本研究通过观察即刻加载的微种植体支抗周围骨界面组织学变化,旨在探索即刻加载是否会影响微种植体支抗的稳定性.方法 本试验选用成年狗1只,16枚正畸用微种植体植入狗的下颌骨后即刻施加1.5 N力,施力9周后狗被处死.骨标本作病理切片后进行组织学观察和测量.结果 微种植体可以承受即刻加载的1.5 N正畸力而无松动.组织学观察显示骨-微种植体界面有骨组织沉积,没有纤维组织生成,即刻加载的正畸力没有影响骨细胞在微种植体表面的沉积.结论 在严格控制植入创伤、加载力量大小的前提下,微种植体的即刻加载是可行的.

  15. 隧道锚围岩拉拔模型试验研究及数值模拟%Pull-out model test for tunnel anchorage and numerical analysis

    Institute of Scientific and Technical Information of China (English)

    胡波; 赵海滨; 王思敬; 刘海宁; 彭运动; 刘晓丽; 张晓平

    2009-01-01

    采用现场模型试验同FLAC3D数值试验相结合进行对比研究.介绍了坝陵河大桥西锚碇1:20、1:30现场模型试验,研究发现锚碇横截面位移呈马鞍型,向两端逐渐收敛,轴线方向呈梯形分布,围岩残余变形率呈V形分布,相同应力水平下,大尺寸模型的监测位移较大.数值试验发现,应力分布具有明显的分段特征,沿锚体呈不对称分布,可能的破坏方式是锚体带动周边一定范围岩体发生塞体状的整体拉剪复合破坏.设计和施工过程中应对显著变形区及破损区内的岩体进行重点加固.

  16. Orthodontic treatment of condylar fracture in children with implant anchorage%固定矫治器联合种植体支抗正畸治疗儿童髁突骨折

    Institute of Scientific and Technical Information of China (English)

    林有籁; 午君武; 郑松

    2013-01-01

    目的 观察正畸固定矫治器联合种植体支抗牵引固定儿童髁突骨折的治疗效果.方法 选取年龄为7~18岁,临床确诊为儿童髁突骨折的病例8例.即刻粘结正畸固定矫治器,植入种植体支抗,上颌间接支抗联合颌间牵引固定复位.结果 所有患者经治疗后均取得良好的临床疗效.张口度,咬合关系,咀嚼功能恢复正常,颌面部发育正常.全景片示髁突骨折逐渐恢复.结论 正畸固定矫治器联合种植体支抗牵引固定是临床上一种有效的治疗儿童髁突骨折的方法.

  17. The Opium Trade at Golden-star Anchorage Before and After the Opium War%鸦片战争前后金星门的鸦片贸易

    Institute of Scientific and Technical Information of China (English)

    魏雅丽

    2013-01-01

    位于广东珠江口西侧的金星门,在鸦片战争前后以其独特的地理位置和有利的条件,从19世纪20年代外国鸦片船的偶然碇泊所,发展到30年代外国鸦片船的固定碇泊所,四五十年代则成为广州市场甚至整个珠江三角洲市场鸦片的重要供应地.对金星门鸦片贸易的个案作较为深入的分析,对探讨鸦片战争前后中西关系的演变,有一定的学术价值.

  18. A preliminary overview of skin and skeletal diseases and traumata in small cetaceans from South American waters. SC/59/DW4, International Whaling Commission/SC, Anchorage, Alaska, May 2007

    OpenAIRE

    Van Bressem, M.-F.; Van Waerebeek, K.; Reyes, J; Félix, F.; M. Echegaray; Siciliano, S.; Di Beneditto, A.P.; Flach, L.; Viddi, F.; Avila, I.C.; Bolaños, J.; Castineira, E.; Montes, D.; Crespo, E.; Flores, P. A. C.

    2007-01-01

    Miscellaneous lesions of the skin and skeletal system, and external traumata were observed in 558 of 7,400 specimens of 12 odontocete species from the waters of Colombia, Ecuador, Peru, Chile, Argentina, Uruguay, Brazil and Venezuela examined in 1984-2007. Tattoo skin disease (TSD), lobomycosis-like and cutaneous diseases of unknown aetiology seem to be emerging in several populations and, in some cases, may be associated with chemical and organic water pollution. TSD was observed in eight sp...

  19. EXPERIMENTAL STUDY ON SAND CONSOLIDATED ANCHORAGE PRESTRESSED BOLT AND ITS APPLICATIONS%砂固结内锚头预应力锚杆试验研究及应用

    Institute of Scientific and Technical Information of China (English)

    覃卫民; 葛修润; 王浩

    2007-01-01

    为将砂固结内锚头预应力锚杆推广应用到锚固工程中,在长江三峡工程砂石料场及湖南凤滩电站地下厂房开展应用试验研究.通过三峡工程砂石料场边坡12根(φ) 32 mm高强材质锚杆现场试验研究,提出此类锚杆的设计方法和施工工艺,对其锚固的长期稳定性进行预应力监测.根据凤滩电站工程实际情况进行技术创新,研究出一种刚性封口的新型砂固结内锚头预应力锚杆,获得国家专利局授权发明专利.

  20. TESTING STUDY AND NUMERICAL SIMULATION ON SAND-CONSOLIDATED-ANCHORAGE-PRESTRESSED BOLT%砂固结预应力锚杆的试验及其数值模拟

    Institute of Scientific and Technical Information of China (English)

    陈荣; 彭伟东; 尹建华; 胡正东; 葛修润; 丰定祥

    2000-01-01

    砂固结预应力锚杆的锚固力是由砂体与锚孔壁之间的摩擦力提供的. 设计了室内试验和现场试验, 并对这项技术作了深入地研究. 基于室内试验成果, 对现场试验作了数值模拟分析.

  1. 33 CFR 110.74a - Manatee River, Bradenton, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Manatee River, Bradenton, Fla... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74a Manatee River, Bradenton, Fla. The waters of the Manatee River enclosed by a line beginning at latitude 27°31′18.6″ N. longitude 82°36′49.2″...

  2. 33 CFR 110.81 - Muskegon Lake, Mich.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Muskegon Lake, Mich. 110.81... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.81 Muskegon Lake, Mich. (a) Muskegon Lake West. The waters of the southwest side of Muskegon Lake enclosed by a line beginning at latitude 43°13′24″...

  3. 3 CFR - Continuation of the National Emergency Relating to Cuba and of the Emergency Authority Relating...

    Science.gov (United States)

    2010-01-01

    ... Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and Movement of Vessels... Emergency Relating to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and... north of Cuba. In July 1996 and on subsequent occasions, the Cuban government stated its intent...

  4. 33 CFR 110.72 - Blackhole Creek, Md.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Blackhole Creek, Md. 110.72... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72 Blackhole Creek, Md. The waters on the west side of Blackhole Creek, a tributary of Magothy River, southwest of a line bearing 310°30′ from the most...

  5. Mechanical mechanism analysis of tension type anchor based on shear displacement method

    Institute of Scientific and Technical Information of China (English)

    XIAO Shu-jun; CHEN Chang-fu

    2008-01-01

    Based on the fact that the shear stress along anchorage segment is neither linearly nor uniformly distributed, the load transfer mechanism of the tension type anchor was studied and the mechanical characteristic of anchorage segment was analyzed. Shear stress-strain relationship of soil surrounding anchorage body was simplified into three-folding-lines model consisting of elastic phase, elasto-plastic phase and residual phase considering its softening eharaeteristic. Meanwhile, shear displacement method that has been extensively used in the analysis of pile foundation was introduced. Based on elasto-plastic theory, the distributions of displacement, shear stress and axial force along the anchorage segment of tension type anchor were obtained, and the formula for calculating the elastic limit load was also developed accordingly. Finally, an example was given to discuss the variation of stress and displacement in the anchorage segment with the loads exerted on the anchor, and a program was worked out to calculate the anchor maximum bearing capacity. The influence of some parameters on the anchor bearing capacity was discussed, and effective anchorage length was obtained simultaneously. The results show that the shear stress first increases and then decreases and finally trends to theresidual strength with increase of distance from bottom of the anchorage body, the displacement increases all the time with theincrease of distance from bottom of the anchorage body, and the increase of velocity gradually becomes greater.

  6. 33 CFR 110.25 - Salem Sound, Mass.

    Science.gov (United States)

    2010-07-01

    ... described in 33 CFR 110.25(a) to the point of beginning. (f) Marblehead Harbor, Marblehead, MA. The area... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Salem Sound, Mass. 110.25 Section... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.25 Salem Sound, Mass. (a) Beverly Harbor, north of...

  7. 33 CFR 110.30 - Boston Harbor, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Boston Harbor, Mass. 110.30... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.30 Boston Harbor, Mass. (a) Vicinity of South Boston... the local Harbor Master, Hull, Mass. (m) Hingham Harbor Area 1. Beginning at position latitude...

  8. Vertical Equilibrium of Sheet Pile Walls with Emphasis on Toe Capacity and Plugging

    DEFF Research Database (Denmark)

    Iversen, Kirsten Malte; Augustesen, Anders Hust; Nielsen, Benjaminn Nordahl

    it impossible to design the anchorage with anchor plates, and the anchorage is therefore often designed as bored and injected soil anchors. Reasons for design and establishment make it is necessary to construct these anchors with an inclination. Inclining anchors imply that larger forces need to be transferred...

  9. 33 CFR 110.77 - Amistad Reservoir, Tex.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Amistad Reservoir, Tex. 110.77... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.77 Amistad Reservoir, Tex. (a) Diablo East, Tex. That portion of the Amistad Reservoir enclosed by a line connecting the following points, excluding a...

  10. 33 CFR 110.4 - Penobscot Bay, Maine.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.4 Penobscot Bay, Maine. (a) Rockland Harbor. Beginning... buoys shall be directed to the local government. Fixed mooring piles or stakes are prohibited. (b... will be allowed. Fixed mooring piles or stakes are prohibited. All moorings must be so placed that...

  11. 33 CFR 110.5 - Casco Bay, Maine.

    Science.gov (United States)

    2010-07-01

    ... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.5 Casco Bay, Maine. (a) Beals Cove, West side of Orrs... anchored, shall at any time extend beyond the limits of the area. Fixed mooring piles or stakes are.... Fixed mooring piles or stakes are prohibited. All moorings must be so placed so that no vessel...

  12. Transversely Compressed- and Restrained Shear Joints

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Hansen, Christian Skodborg

    2013-01-01

    Anchorage of FRP strengthening systems where the deformation perpendicular to the FRP material is restrained or a compressive force is applied on the strengthening, seems to provide ductility, increased utilization of the FRP and failure modes which can be controlled through the anchorage method....... and compared with tests. It is seen that the theory correlates well with the experimental results....

  13. Test on Beams Strengthened with Multi-layers Carbon Fiber Sheets Anchored by Wave-shaped-gear-grip Anchorage%锚固多层碳纤维布加固钢筋混凝土梁的试验研究

    Institute of Scientific and Technical Information of China (English)

    卓静; 李唐宁; 章庆学; 周密

    2006-01-01

    为了进一步验证采用波形齿夹具锚锚固碳纤维布可以完全避免碳纤维布端部的剥离破坏,分别对采用粘贴4,6,8,10层碳纤维布加固的4根钢筋混凝土梁进行了抗弯加载试验.试验结果表明,由于采用了波形齿夹具锚作为碳纤维布的端部锚固措施,尽管粘贴的碳纤维布层数较多,并且碳纤维布的粘贴质量也较差,然而抗弯加固的碳纤维布都没有出现端部的剥离失效问题,并且碳纤维布的强度也得到了较充分的发挥.

  14. 采用异体腘绳肌腱Rigidfix交叉钉与Intrafix膨胀挤压螺钉重建前交叉韧带初步报道%ANTERIOR CRUCIAL LIGAMENT RECONSTRUCTION WITH ALLOGRAFT HAMSTRING FIXED BY RIGIDFIX AND INTRAFIX ANCHORAGES

    Institute of Scientific and Technical Information of China (English)

    白伦浩; 王佳时; 傅永慧; 付勤

    2007-01-01

    目的 探讨关节镜下采用可吸收Rigidfix交叉钉与Intrafix 膨胀挤压螺钉固定异体腘绳肌腱移植、重建膝关节前交叉韧带(anterior cruciate ligament, ACL)的手术方法和近期疗效.方法 2006年1月~12月,取低温冷冻异体腘绳肌腱作为ACL的替代物,关节镜下应用可吸收Rigidfix交叉钉与Intrafix 膨胀挤压螺钉固定治疗ACL损伤21例.其中男13例,女8例;年龄18~53岁.损伤原因:交通伤7伤,运动损伤11例,其他原因3例.合并Ⅱ度内侧副韧带(medial collateral ligament, MCL)及半月板损伤10例,内外侧半月板同时损伤3例,外侧半月板损伤6例,单纯ACL损伤2例.受伤至手术时间为7 d~3个月.手术前、后按照Lysholm膝关节评分标准进行评价. 结果 术后21例均获3~9个月随访,平均5.8个月.术后膝关节活动范围19例超过120°;1例合并MCL损伤术后3个月屈膝受限80°,二期行关节镜下松解术;1例因排斥反应关节肿胀、发热,行关节镜冲洗后缓解.术后21例前抽屉试验、轴移试验均阴性,Lanchman试验Ⅰ度阳性1例,其余为阴性.Lysholm评分从术前56.73±6.58分增加至术后88.14±7.02分,差异有统计学意义(P<0.01). 结论 关节镜下采用可吸收Rigidfix交叉钉与Intrafix 膨胀挤压螺钉固定异体腘绳肌腱重建膝关节ACL,手术方法简便,固定确实可靠,患者创伤小;术后早期康复锻炼,能快速恢复功能.

  15. The Clinical Application of Mini-screw Implant Anchorage in the orthodontic Treatment Of Adult Bimaxillary Protrusion%微螺钉种植体支抗在成人双颌前突正畸治疗中的临床应用

    Institute of Scientific and Technical Information of China (English)

    赵红卫; 杨雨民

    2010-01-01

    目的:总结微螺钉种植体支抗在临床中治疗成人双颌前突的经验,评价微螺钉种植体在正畸治疗中作为强支抗内收前牙的有效性.方法:从临床病例中选择12例成人双颌前突患者,矫治设计均为拔除4颗第一前磨牙,在上下颌第一恒磨牙与第二恒磨牙或上下颌第一恒磨牙与第二前磨牙之间的颊侧根尖部植入微螺钉种植体作为强支抗,共48颗,以每侧200g力滑动法关闭间隙.在治疗前后均拍摄头颅定位侧位片及全颌曲面断层片,比较双颌前突患者治疗前后前牙内收情况及第一恒磨牙位置的变化.结果:12例成人双突患者面型均得到明显改善,应用微螺钉种植体支抗顺利完成正畸治疗,第一恒磨牙位置稳定.结论:微螺钉种植体支抗可避免上颌磨牙的前移,能为上下颌前突畸形的矫治提供有效的支抗.

  16. 种植体支抗辅助非拔牙矫正成人Ⅱ类2分类错(牙合)的临床研究%Clinical study of non-extraction orthodontic treatment for adult Angle's Ⅱ Division 2 malocclusion assisted by mini-screw implant anchorage

    Institute of Scientific and Technical Information of China (English)

    冯贻苗; 万澎波; 娄新田; 王一霖

    2014-01-01

    目的 探讨微型种植体支抗辅助矫治成人安氏Ⅱ类2分类错(牙合)的临床作用机制.方法 选择12例安氏Ⅱ类2分类病例,男4例,女8例,年龄18~38岁,平均21.0岁.应用微型种植体支抗牵引上牙列整体向后移动,压低上前牙,分析治疗前后患者牙齿、颌骨及软组织变化.结果 上颌中切牙矢状向牙冠基本保持不动,牙根平均远中移动3.63 mm,平均倾斜比率为6050%,牙冠压低4.60 mm.上颌第一前磨牙牙冠平均远中移动3.25 mm,牙根远中移动3.65 mm,平均倾斜比率为112.3%,牙冠压低2.90 mm.上颌第一磨牙牙冠平均远中移动3.11 mm,牙根远中移动3.21 mm,平均倾斜比率为103.2%,牙冠压低1.17 mm.上颌第二磨牙牙冠平均远中移动3.22 mm,牙根平均远中移动3.15 mm,平均倾斜比率为97.8%,压低0.69 mm.结论 运用微型种植体支抗可以有效地使上颌牙列整体后移、压低上前牙并改建上颌前牙区齿槽骨形态,是非拔牙矫正安氏Ⅱ类内倾型深覆(牙合)患者的有效方法.

  17. Light microscopic observation on immediate and early loading of mini screw implants used for orthodontic anchorage in Beagle dogs%Beagle犬上颌骨微钛螺纹钉种植体支抗即刻和早期加载的光镜观察

    Institute of Scientific and Technical Information of China (English)

    孙嵘; 范春香; 吴丽萍

    2009-01-01

    目的 通过光镜观察不同加载时间及加载力值对微钛螺纹钉种植体-骨结合界面的影响.方法 将90枚微钛螺纹钉种植体(mini screw implant, MSI)分为9组,植入5只Beagle犬的上颌骨.分别于即刻、第2周、第4周、第8周加载100 g或300 g的水平力,对照组不加力.第20周处死动物取材.垂直于种植体长轴方向切片,制成50 μm左右的硬组织切片,苦味酸-品红染色,在光学显微镜下观察种植体-骨结合界面的密合程度并计算种植体-骨结合率.结果 本实验共有9枚MSI松动.其余MSI在光镜下显示与骨组织直接接触,未见纤维组织长入.各组MSI与周围骨组织的平均骨结合率为(45.28±23.89)%.各组间骨结合率差别无统计学意义.结论 在一定骨质及初期稳定性的保证下,在Beagle犬的上颌骨MSI即刻加载300 g以内的水平力是可行的.

  18. 微小种植体支抗与传统强支抗在成人双颌前突尖牙远移中的比较%Comparative study of mini-implant for orthodontic anchorage and traditional anchorge in cuspid retration in adult patients with bimaxillary protrusion

    Institute of Scientific and Technical Information of China (English)

    刘鑫; 段银钟; 刘岚

    2004-01-01

    目的:研究微小种植体在成人双颌前突矫治尖牙远移中的支抗应用,同时与口外弓配合Nance弓的传统支抗相比较.方法:24例成人双颌前突患者随机分为2组,试验组尖牙远移时应用微小种植体做为支抗,对照组远移尖牙时则利用口外弓配合Nance弓的传统支抗,通过尖牙远移前后的X线头影测量变化来判断2支抗丧失情况并做组间比较.结果:2组患者在3~6个月后远移尖牙到位,试验组上颌第一磨牙前移0.85mm,上切牙腭侧移动1.82mm对照组上颌第一磨牙前移0.91mm,上切牙腭侧移动2.02mm.方差分析可见2组间无差异.结论:微小种植体是一种具有稳固、生物相容性好、舒适等特点的支抗,完全可以代替口外弓配合Nance弓的传统强支抗,在尖牙远移过程中发挥强大的支抗作用.

  19. 微种植支抗关闭正畸拔牙间隙对下颌垂直向位置的影响%Influence to the mandibular plane in vertical dimension in extraction-orthodontic treatment applying mini-implant anchorage

    Institute of Scientific and Technical Information of China (English)

    李建军; 施生根

    2013-01-01

    目的 分析应用微种植支抗关闭正畸拔牙间隙对下颌垂直向位置的影响.方法 选择2008年1月~2011年12月解放军306医院患者20例,将应用微种植支抗的高角正畸拔牙患者进行5项与下颌垂直位置有关的指标测量,对治疗前后指标进行统计学分析.结果 上颌中切牙(U1)治疗前后[(33.01±2.43)、(30.70±2.53) mm]垂直向位置变化具有高度统计学意义(P<0.01);上颌第一磨牙(U6)平均压低治疗前后[(23.93±1.99)、(22.78±2.02) mm]垂直向位置变化具有统计学意义(P<0.05);治疗前后下颌平面角及合平面角(GOGN-SN、FMA、Occp-FH)变化差异具有统计学意义(P<0.05).结论 种植支抗辅助高角拔牙正畸治疗后,上颌中切牙及上颌第一磨牙呈现一定程度压低,下颌平面角及合平面角减小,下颌产生一定程度逆时针旋转.

  20. The animal experiment on the stability of mini-screws anchorage implant under different orthodontic force%不同受力条件下微螺钉支抗种植体稳定性的动物实验研究

    Institute of Scientific and Technical Information of China (English)

    石咏梅; 王翔; 王虎中; 郭家平; 彭艳芳

    2005-01-01

    目的:探讨微螺钉支抗种植体在不同受力条件下的稳定性.方法:观察在300 g力值下,以微型螺钉种植体为支抗,牵拉犬上下颌尖牙;在150 g力值下压低上颌前牙;在300 g、400 g、600 g逐渐加力和600 g即刻加力情况下,种植体交互牵引.观察尖牙横向位移、前牙压低位移以及微螺钉支抗种植体的相互位移情况.结果:种植体拉尖牙移动、压低前牙有效.在600 g力的条件下种植体发生相互位移,并有部分种植体发生松动.结论:微螺钉种植体支抗的稳定性与受力大小有关.

  1. Experimental and numerical simulation study on the progressive damage on the anchorage by the dynamic pressure in mining%采动压力对锚杆支护结构渐进损伤的数值模拟和实验研究

    Institute of Scientific and Technical Information of China (English)

    李青锋; 周泽; 朱川曲

    2015-01-01

    为分析底板巷道锚杆支护结构在采动压力作用下锚固段损伤机理及其承载模式,提高树脂锚杆支护在煤矿现场应用的可靠性,首先采用UDEC数值模拟软件模拟了上覆煤层开采对前方底板巷道的影响,分析了采动应力对顶、帮锚杆支护结构的作用响应;然后采用FLAC数值模拟软件模拟了树脂锚杆锚固段的承载及变形,得到了树脂锚杆在一定载荷和围压作用下动力响应;最后以混凝土试块模拟围岩,并在混凝土试块预留孔中锚固了树脂锚杆进行锚杆拉拔试验,并在拉拔同时采用弹性波无损检测仪进行锚杆无损动力检测.结果表明,树脂锚杆的锚固损伤是一种渐进式破坏过程,这种渐进式破坏和锚杆的有效锚固长度可以通过弹性波无损检测方法准确检测,并推断锚杆的实时承载力,从而提高树脂锚杆支护在煤矿现场应用的时效性.%This research is conducted in order to analyze damage mechanism and bearing mode of re-sin bolt anchoring section of bolt support structure in floor railway under the dynamic pressure in min-ing, and to improve the reliability of resin bolting in coal mine field applications. First, the mine-induced stress of floor railway is simulated by UDEC while the overlying seam is mining, and the reaction of roof bolt and side bolt support structure is analyzed. Then, the bearing and deformation of resin bolt anchoring section are simulated by FLAC, and the dynamic response of resin bolt under cer-tain load and confining pressure is obtained. Finally, surrounding rock with concrete block is simulated, and bolt pullout test is carried out in the prepared hole in which resin bolt have been anchored, at the same time elastic wave test instrument is used to do nondestructive test for the bolt. The test result shows that 1) the process of resin bolt anchoring damage is gradual, 2) the gradual failure and the effec-tive anchoring length can be detected by elastic wave nondestructive test, and that 3) the real-time bear-ing capacity of the bolt can be deduced, so as to improve the timeliness of resin bolting in coal mine field applications.

  2. 基于全桥组合有限元模型的独塔斜拉桥索梁锚固结构计算分析%Calculation and Analysis of Cable-Pylon Anchorage Structure of A Single Tower Cable-Stayed Bridge based on Full Bridge Finite Element Model

    Institute of Scientific and Technical Information of China (English)

    张子尧; 庞竞拓

    2014-01-01

    利用全桥结构仿真分析技术建立全桥组合有限元模型;将全桥模型索梁锚固段的网格加密,详尽模拟钢锚箱锚固结构;计算分析索梁锚固结构在恒载和车辆荷载作用下的应力分布,并提出构造建议.

  3. LABORATORY TESTING STUDY ON SAND-CONSOLIDATED- ANCHORAGE-PRESTRESSED BOLT AND NEW SUGGESTION ON SAND STRENGTH THEORY%砂固结锚固室内试验及砂土强度特性理论的再认识

    Institute of Scientific and Technical Information of China (English)

    陈荣; 邓学璟; 胡正东; 葛修润; 丰定祥

    2000-01-01

    砂固结内锚头预应力锚杆的锚固力是由砂体与锚孔壁之间的摩擦力提供的,设计的室内试验测出了摩擦力的分布曲线,基于本试验成果对目前的砂土强度特性理论提出了一些看法.

  4. Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation

    OpenAIRE

    Hua YANG; Lawrence, Harshani R.; Kazi, Aslamuzzaman; Gevariya, Harsukh; Patel, Ronil; Luo, Yunting; Rix, Uwe; Schonbrunn, Ernst; Lawrence, Nicholas J.; Sebti, Said M.

    2014-01-01

    Aurora A and JAK2 kinases are involved in cell division and tumor cell survival, respectively. Here we demonstrate that ectopic expression of Aurora A and JAK2 together is more effective than each alone at inducing non-transformed cells to grow in an anchorage-independent manner and to invade. Furthermore, siRNA silencing or pharmacological inhibition of Aurora A and JAK2 with Alisertib and Ruxolitinib, respectively, is more effective than blocking each kinase alone at suppressing anchorage-d...

  5. Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

    DEFF Research Database (Denmark)

    Lawrenson, Kate; Li, Qiyuan; Kar, Siddhartha;

    2015-01-01

    associated with HGSOC risk (P≤10−5). For three cis-eQTL associations (Pfunctional role of each candidate by perturbing expression of each gene in HGSOC precursor cells. Overexpression of HOXD9 increases anchorage...

  6. Eagle river flats bird dieoff: A summary of findings 1988

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Since 1982, periodic waterfowl die-offs have been documented at Ft. Richardson Army Base, Anchorage, Alaska in an area at the mouth of Eagle River known as Eagle...

  7. 78 FR 46596 - Secretarial Commission on Indian Trust Administration and Reform

    Science.gov (United States)

    2013-08-01

    ..., 2013, to: trustcommission@ios.doi.gov to ensure adequate meeting packets will be made available.... 6th Avenue, Anchorage, Alaska 99501. We encourage you to RSVP to trustcommission@ios.doi.gov by...

  8. Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

    DEFF Research Database (Denmark)

    Hong, Xin; Nguyen, Thanh Hung; Chen, Qingfeng;

    2014-01-01

    Cancer genomes accumulate numerous genetic and epigenetic modifications. Yet, human cellular transformation can be accomplished by a few genetically defined elements. These elements activate key pathways required to support replicative immortality and anchorage independent growth, a predictor of ...

  9. 78 FR 78824 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-12-27

    ... Modeling Workshop. SUMMARY: The workshop will be held January 14-17 at the Hilton Hotel, 500 West Third....m. to 5 p.m. ADDRESSES: The workshop will be held at the Anchorage Hilton Hotel, 500 West...

  10. Formuleren onderzoeksvraag en theoretische verankering

    NARCIS (Netherlands)

    Bijker, Monique; Wetzels, Sandra

    2012-01-01

    Bijker, M. M., & Wetzels, S. A. J. (2012, 10 July). Formuleren onderzoeksvraag en theoretische verankering [Formulating a research question and its anchorage in theory]. Presentation given in project 'Professionaliseringstraject: onderzoeksvaardigheden van docenten' of Fontys MER, Eindhoven, The Net

  11. 33 CFR 110.51 - Groton, Conn.

    Science.gov (United States)

    2010-07-01

    ... REGULATIONS Special Anchorage Areas § 110.51 Groton, Conn. The waters between an unnamed cove and Pine Island... the anchor of a vessel at anchor may be used. Fixed mooring pilings or stakes are prohibited....

  12. 30 CFR 250.415 - What must my casing and cementing programs include?

    Science.gov (United States)

    2010-07-01

    ... effect, proper anchorage, and well control. (e) A statement of how you evaluated the best practices included in API RP 65, Recommended Practice for Cementing Shallow Water Flow Zones in Deep Water...

  13. 50 CFR 29.21-2 - Application procedures.

    Science.gov (United States)

    2010-10-01

    ... “Procedures for the Protection of Historic and Cultural Properties” (36 CFR, part 800). Concerning the... including the impact on air and water quality; scenic and esthetic features; historic, architectural..., 1101 E. Tudor Road, Anchorage, Alaska 99503....

  14. 14 CFR 93.51 - Applicability.

    Science.gov (United States)

    2010-01-01

    ... AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area § 93.51... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Applicability. 93.51 Section 93.51..., Terminal Area....

  15. Proposed Becharof Wildlife Refuge headquarters site inventory King Salmon and Naknek

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — As d2 legislation moves through Congress, the Refuges and Resource Planning Divisions of the U.S. Fish and Wildlife Service office in Anchorage work to prepare for...

  16. ATLAS Civil Engineering Point 1

    CERN Multimedia

    2001-01-01

    Different phases of realisation to Point 1: zone of the ATLAS experiment 14-02-2001Realising anchorage, isolations and scaffoldings at UX 15 18-04-2001Concreting the arch and posing the metal reinforcements at UX 15

  17. Reversible Adaptive Plasticity: A Mechanism for Neuroblastoma Cell Heterogeneity and Chemo-Resistance

    OpenAIRE

    AnthonyDSandler

    2012-01-01

    We describe a novel form of tumor cell plasticity characterized by reversible adaptive plasticity in murine and human neuroblastoma. Two cellular phenotypes were defined by their ability to exhibit adhered, anchorage dependent (AD) or sphere forming, anchorage independent (AI) growth. The tumor cells could transition back and forth between the two phenotypes and the transition was dependent on the culture conditions. Both cell phenotypes exhibited stem-like features such as expression of nest...

  18. Application of microarrays to identify and characterize genes involved in attachment dependence in HeLa cells

    OpenAIRE

    Jaluria, Pratik; Betenbaugh, Michael; Konstantopoulos, Konstantinos; Frank, Bryan; Shiloach, Joseph

    2006-01-01

    The ability to modify cellular properties such as adhesion is of interest in the design and performance of biotechnology-related processes. The current study was undertaken in order to evaluate the effectiveness of modulating cellular adhesion in HeLa cells from a genomics perspective. Using DNA microarrays, differences in gene expression between two phenotypically distinct, anchorage-dependent and anchorage-independent, HeLa cell lines were identified. With the aid of several statistical met...

  19. Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production

    OpenAIRE

    Chu, Chia; Lugovtsev, Vladimir; Golding, Hana; Betenbaugh, Michael; Shiloach, Joseph

    2009-01-01

    MDCK cells are currently being considered as an alternative to embryonated eggs for influenza virus propagation and hemagglutinin (HA) production intended for vaccine manufacturing. MDCK cells were found suitable for the virus production but their inability to grow in suspension burdens the process of scale up and hence their production capability. Anchorage-dependent MDCK cells were converted to anchorage-independent cells, capable of growing in suspension as a result of transfection with th...

  20. Stem Cell Derived Extracellular Matrix Enables Survival and Multi Lineage Differentiation within Superporous Hydrogels

    OpenAIRE

    Köllmer, Melanie; Keskar, Vandana; Hauk, Thomas G.; Collins, John M.; Russell, Brenda; Gemeinhart, Richard A.

    2012-01-01

    Hydrophilic poly(ethylene glycol) diacrylate (PEGDA) hydrogel surfaces resist protein adsorption and are generally thought to be unsuitable for anchorage dependent cells to adhere. Intriguingly, our previous findings revealed that PEGDA superporous hydrogel scaffolds (SPHs) allow anchorage of bone marrow derived human mesenchymal stem cells (hMSCs) and support their long term survival. Therefore, we hypothesized that the physicochemical characteristics of the scaffold impart properties that c...

  1. A damage detection model for unbonded post-tensioning tendons based on relative strain variation in multi-strand anchors

    Science.gov (United States)

    Abdullah, A. B. M.; Rice, Jennifer A.; Hamilton, H. R.

    2014-03-01

    Post-tensioned segmental bridges are common throughout the US; however, in recent years, the incidence of tendon failure in bonded post-tensioned bridges has raised questions regarding their design, construction, and maintenance. These failures have led to the investigation of the applicability of using replaceable unbonded tendons in segmental construction and new methods for monitoring their condition. This paper presents a damage detection algorithm to identify strand breakage in unbonded tendons based on the relative variation of strains in the anchorage. In unbonded construction, the anchorage assembly usually undergoes a severe stress-state condition as the entire prestressing force only passes through the deviator and end anchorage locations. The strain distribution in the anchorage mechanism, therefore, goes through significant changes in response to the breakage of an individual wire or an entire strand in a multi-strand arrangement. In this way, breakage of a post-tensioning strand can be identified by observing a non-uniform variation of the strain field over the anchorage region in contrast to a uniform variation of strains due to environmental or traffic loading. A reduced scale laboratory experiment is performed followed by an extensive finite element simulation to conduct a parametric study with wire/strand breakages at different locations on multi-strand anchorages commonly used in industry. Based on the observed strain variations from simulation, a damage detection model is proposed that enables the adoption of an automated monitoring strategy to characterize the breakage programmatically.

  2. Orthodontic anchoring techniques and its influence on pain, discomfort, and jaw function--a randomized controlled trial.

    Science.gov (United States)

    Feldmann, Ingalill; List, Thomas; Bondemark, Lars

    2012-02-01

    The aim of this trial was to evaluate and compare perceived pain, discomfort, and jaw function impairment between orthodontic treatments combined with skeletal anchorage and treatment using conventional anchorage with headgear or transpalatal bar. A total of 120 adolescent patients in order to start orthodontic treatment were consecutively recruited and randomized into three groups with different anchorage. Group A underwent installation of a skeletal anchorage (Onplant or Orthosystem implant), group B received headgear, and group C a transpalatal bar. Questionnaires were used to assess pain intensity, discomfort, analgesic consumption, and jaw function impairment from baseline to the end of treatment. Pain scores overall peaked on day 2 and were almost back to baseline on day 7. The site with the highest pain scores during treatment was incisors in contact but with no differences between groups. Pain intensity from molars was significantly less in the skeletal anchorage group A compared to the transpalatal bar group C the first 4 days in treatment and with no sign differences compared to headgear. The results confirm that there were very few significant differences between patients' perceptions of skeletal and conventional anchorage systems during orthodontic treatment. Consequently, these new appliances were well accepted by the patients in a long time perspective and can thus be recommended.

  3. Application of pre-stressed technology in the crossing construction of the China–Myanmar Gas Pipeline

    Directory of Open Access Journals (Sweden)

    Xuejun Wang

    2015-01-01

    Full Text Available Concrete structure is commonly used in the anchorages of a large cable-suspended pipeline crossing construction. With the increase of span and load, the stress on the concrete anchorages may rise rapidly. In case of traditional anchoring structure fixed by anchor rods, concrete cracking will occur, thereby reducing the anchorage life. To solve this problem, the pre-stressed structure was designed to effectively improve the efficiency of anchoring and reduce engineering cost. In the crossing construction of China–Myanmar Gas Pipeline, the pre-stressed technology was used to establish an effective pre-stressed anchoring system, which integrates the pre-stressed structures (e.g. tunnel anchorages in the anchors and the optimization measures (e.g. positioning mode, anchorage structure, concrete placement, pre-stressed, and medium injection, in line with the crossing structure and load features of this project. The system can delay the occurrence of concrete cracking and enhance the stress durability of the structure and anchoring efficiency. This technology has been successfully applied in the crossing construction of China–Myanmar Gas Pipeline, with good economic and social benefits, indicating that this technology is a new effective solution to the optimization of suspended pipeline anchorage structures, providing technical support for the development of pipeline crossing structure.

  4. Application of 3D sonar seepage detecting technology in deep foundation pit projects:case of anchorage base of Miaozui Yangtze River Bridge at Yichang, Hubei%三维声纳渗流探测技术在深基坑工程中的应用——以湖北宜昌庙嘴长江大桥锚碇基坑工程为例

    Institute of Scientific and Technical Information of China (English)

    朱敏; 郭晓刚; 董志超

    2015-01-01

    为了在深基坑开挖前提前判断基坑侧壁渗漏点的具体位置,以紧邻长江边的深基坑为工程背景,简要介绍了三维声纳渗流探测的原理,侧重论述了声纳探测技术的实施方法及具体施工布置要求. 通过对基坑地连墙外各观测孔声纳渗流检测数据的计算分析、类比和评估,较为全面掌握了基坑在内外水头作用下的渗流情况. 在实际开挖过程中,通过现场观测,声纳探测的渗漏点与现场情况基本一致. 总结了声纳探测技术的优缺点,从应用需求上指出了下步应探索的领域.%Taking a deep foundation pit projects near to Yangtze River as a case, we applied 3D sonar seepage detecting meth-od to master the side wall seepage condition before the pit excavation. The principle of 3D sonar seepage detecting is introduced, especially the detecting procedure as well as the detail construction layout are discussed. By analyzing and comparing the sonar detecting data outside the diaphragm wall of foundation pit, we understood the overall condition of pit seepage under the influence of outside-inside water head. In the later foundation pit excavation, the detecting results provided by sonar detecting were in ac-cordance with the measured data. Finally, the pros and cons of sonar detecting technology are summarized, and the next explora-tion field is pointed out in terms of application requirement.

  5. Application of microarrays to identify and characterize genes involved in attachment dependence in HeLa cells.

    Science.gov (United States)

    Jaluria, Pratik; Betenbaugh, Michael; Konstantopoulos, Konstantinos; Frank, Bryan; Shiloach, Joseph

    2007-05-01

    The ability to modify cellular properties such as adhesion is of interest in the design and performance of biotechnology-related processes. The current study was undertaken in order to evaluate the effectiveness of modulating cellular adhesion in HeLa cells from a genomics perspective. Using DNA microarrays, differences in gene expression between two phenotypically distinct, anchorage-dependent and anchorage-independent, HeLa cell lines were identified. With the aid of several statistical methods and an extensive literature search, two genes were selected as potential targets for further study: siat7e and lama4. Subsequently, experiments were carried out to investigate the effects of siat7e and lama4 separately, on adhesion in HeLa cells by altering their expression in vivo. Decreasing the expression of siat7e, a type II membrane glycosylating sialyltransferase, in anchorage-independent HeLa cells using short interfering RNA (siRNA) resulted in greater aggregation (i.e. clumping) and morphological changes as compared to untreated anchorage-independent HeLa cells. Similar effects were seen in anchorage-independent HeLa cells when the expression of lama4 which encodes laminin alpha4, a member of the laminin family of glycoproteins, was enhanced as compared to untreated anchorage-independent HeLa cells. Using a shear flow chamber, an attachment assay was developed; illustrating either increased expression of siat7e or decreased expression of lama4 in anchorage-dependent HeLa cells reduced cellular adhesion. Collectively, the results of this study are consistent with the roles siat7e and lama4 play in adhesion processes in vivo and indicate modifying the expression of either gene can influence adhesion in HeLa cells. The strategy of applying bioinformatics techniques to characterize and manipulate phenotypic behaviors is a powerful tool for altering the properties of various cell lines for desired biotechnology objectives. PMID:17240181

  6. Analisis parametrico de las variables que influyen en el comportamiento adherente de las armaduras pretesas en el hormigon

    Science.gov (United States)

    Arbelaez Jaramillo, Cesar Augusto

    Prestressed concrete technique through the use of prestressed reinforcement is extended in the precast concrete industry. This technique consists on casting a concrete element over a previously prestressed reinforcement, proceeding to release once the concrete has reached a determined strength so the prestressed stress introduced to the reinforcement be transmitted, by bond, to concrete. The bond behaviour of prestressed reinforcement includes two phenomena: prestress transmission from the reinforcement to concrete and anchorage of the reinforcement. This bond behaviour is characterized by mean of two lengths: transmission length and anchorage length. The good design of these lengths is a basic and fundamental aspect in the project of precast prestressed concrete elements to guaranty the appropriate transmission of prestress and to allow the anchorage of the reinforcement along the structural element service life. The influence of the parameters related to the concrete dosage on the transmission and anchorage lengths of prestressing strands have been analyzed. The ECADA test method has been applied. With this method the operations of transmission of prestress and anchorage of the reinforcement are sequentially done. The transmission and anchorage lengths are determined from the force control supported by the reinforcement testing series of specimens with different embedment lengths. The differentiation of the concepts of anchorage length without slips and with slips has been proposed. The relationship of the parameters of dosage with the bond stress and the registered slips during the processes of transmission and anchorage has been studied. Expressions to value the slips distribution of the reinforcement in the transmission zone and in the anchorage zone have been proposed. A study on the determination of the transmission length from the free reinforcement slip end has been done and the viability to experimentally determine the transmission length from the slips

  7. Evaluation of primary stability of innovated orthodontic miniscrew system (STS): An ex-vivo study

    Science.gov (United States)

    Seifi, Massoud

    2016-01-01

    Background Stability is determined as one of the requirements in use of Temporary Anchorage Devices (TAD) in orthodontics. Miniscrew has been a widely used Bone Anchor. Compared with mini-implant that necessitates osseointegration; mechanical retention is a determining factor for primary stability of miniscrew. Studies investigated various ways to increase primary stability. The aim of this study is to introduce a new configuration of miniscrew system which is believed to obtain more primary stability. Material and Methods Freshly ovine mandibles were cut in blocks. Twenty-seven miniscrews (diameter 1.6 × 8 mm; G2, Dual Top Anchor System, Jeil Medical, Seoul, Korea) were inserted in the blocks and divided in 2 experimental groups: single miniscrew and the innovated design “Seifi Twin Screw (STS)”. Primary stability was evaluated by Periotest “M”® device. Results Independent t-test showed a significant difference between 2 experimental groups in periotest evaluation (p< 0.05). STS demonstrated higher primary stability due to its mechanical configuration and design. Conclusions The STS provides higher primary stability and was found to be effective in increased success rate of miniscrew systems from the standpoint of primary stability. Key words:Anchorage procedures, anchorage techniques, orthodontic anchorage procedures, miniscrews, temporary anchorage device. PMID:27398174

  8. Pedicle Screw Fixation Study in Immature Porcine Spines to Improve Pullout Resistance during Animal Testing.

    Science.gov (United States)

    Le Cann, Sophie; Cachon, Thibaut; Viguier, Eric; Miladi, Lotfi; Odent, Thierry; Rossi, Jean-Marie; Chabrand, Patrick

    2015-01-01

    The porcine model is frequently used during development and validation of new spinal devices, because of its likeness to the human spine. These spinal devices are frequently composed of pedicle screws with a reputation for stable fixation but which can suffer pullouts during preclinical implantation on young animals, leading to high morbidity. With a view to identifying the best choices to optimize pedicle screw fixation in the porcine model, this study evaluates ex vivo the impact of weight (age) of the animal, the level of the vertebrae (lumbar or thoracic) and the type of screw anchorage (mono- or bi-cortical) on pedicle screw pullouts. Among the 80 pig vertebrae (90- and 140-day-old) tested in this study, the average screw pullout forces ranged between 419.9N and 1341.2N. In addition, statistical differences were found between test groups, pointing out the influence of the three parameters stated above. We found that the the more caudally the screws are positioned (lumbar level), the greater their pullout resistance is, moreover, screw stability increases with the age, and finally, the screws implanted with a mono-cortical anchorage sustained lower pullout forces than those implanted with a bi-cortical anchorage. We conclude that the best anchorage can be obtained with older animals, using a lumbar fixation and long screws traversing the vertebra and inducing bi-cortical anchorage. In very young animals, pedicle screw fixations need to be bi-cortical and more numerous to prevent pullout. PMID:26451947

  9. Pedicle Screw Fixation Study in Immature Porcine Spines to Improve Pullout Resistance during Animal Testing.

    Directory of Open Access Journals (Sweden)

    Sophie Le Cann

    Full Text Available The porcine model is frequently used during development and validation of new spinal devices, because of its likeness to the human spine. These spinal devices are frequently composed of pedicle screws with a reputation for stable fixation but which can suffer pullouts during preclinical implantation on young animals, leading to high morbidity. With a view to identifying the best choices to optimize pedicle screw fixation in the porcine model, this study evaluates ex vivo the impact of weight (age of the animal, the level of the vertebrae (lumbar or thoracic and the type of screw anchorage (mono- or bi-cortical on pedicle screw pullouts. Among the 80 pig vertebrae (90- and 140-day-old tested in this study, the average screw pullout forces ranged between 419.9N and 1341.2N. In addition, statistical differences were found between test groups, pointing out the influence of the three parameters stated above. We found that the the more caudally the screws are positioned (lumbar level, the greater their pullout resistance is, moreover, screw stability increases with the age, and finally, the screws implanted with a mono-cortical anchorage sustained lower pullout forces than those implanted with a bi-cortical anchorage. We conclude that the best anchorage can be obtained with older animals, using a lumbar fixation and long screws traversing the vertebra and inducing bi-cortical anchorage. In very young animals, pedicle screw fixations need to be bi-cortical and more numerous to prevent pullout.

  10. Stone cladding engineering

    CERN Document Server

    Sousa Camposinhos, Rui de

    2014-01-01

    This volume presents new methodologies for the design of dimension stone based on the concepts of structural design while preserving the excellence of stonemasonry practice in façade engineering. Straightforward formulae are provided for computing action on cladding, with special emphasis on the effect of seismic forces, including an extensive general methodology applied to non-structural elements. Based on the Load and Resistance Factor Design Format (LRDF), minimum slab thickness formulae are presented that take into consideration stress concentrations analysis based on the Finite Element Method (FEM) for the most commonly used modern anchorage systems. Calculation examples allow designers to solve several anchorage engineering problems in a detailed and objective manner, underlining the key parameters. The design of the anchorage metal parts, either in stainless steel or aluminum, is also presented.

  11. Computing of the Anchor by the Method of Three-Dimension Point-Radiate Infinite Elements

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    On the basis of the one-dimension infinite element theory, the coordinate translation and shape function of 3D point-radiate 8-node and 4-node infinite elements are derived. They are coupled with 20-node and 8-node finite elements to compute the compression distortion of the prestressed anchorage segment. The results indicate that when the prestressed force acts on the anchorage head and segment, the stresses and the displacements in the rock around the anchorage head and segment concentrate on the zone center with the anchor axis, and they decrease with exponential forms. Therefore,the stresses and the displacement spindles are formed. The calculating results of the infinite element are close to the theoretical results. This indicates the method is right. This article introduces a new way to study the mechanism of prestressed anchors. The obtained results have an important role in the research of the anchor mechanism and engineering application.

  12. Orthodontic Implants: Concepts for the Orthodontic Practitioner

    Directory of Open Access Journals (Sweden)

    Carlos Nelson Elias

    2012-01-01

    Full Text Available Orthodontic implants have become a reliable method in orthodontic practice for providing temporary additional anchorage. These devices are useful to control skeletal anchorage in less compliant patients or in cases where absolute anchorage is necessary. There are a great number of advantages in this new approach which include easy insertion, decreased patient discomfort, low price, immediate loading, reduced diameter, versatility in the forces to be used, ease of cleaning, and ease of removal. However, a proper management of the screws by the practitioner is necessary in order to increase the success rate of the technique. The purpose of this paper is to update practitioners on the current concepts of orthodontic implants and orthodontic mechanics.

  13. The Optimal Dentition of the Periodontitis Patient

    DEFF Research Database (Denmark)

    Melsen, Birte; Laursen, Morten Godtfredsen

    2014-01-01

    This article focuses on the evolution of orthodontic treatment possibilities developed for degenerating dentitions in adult patients. Indications for such therapy comprise dentition suffering from an aggravation of a malocclusion, horizontal loss of periodontal tissue support, elongation and......, termed “Temporary Anchorage Devices – TADs”, have been designed to facilitate and enhance the effectiveness of orthodontic therapy. It became obvious that with TADs as anchorage, the displacement of teeth into edentulous atrophic areas leads to a build-up of bone that can serve to secure implants later...... of dental implants – are presented in this article, including the importance of subsequent lifelong maintenance to guarantee stability of the achieved result....

  14. O uso de implantes para ancoragem em Ortodontia

    Directory of Open Access Journals (Sweden)

    Mariana Buj

    2005-01-01

    Full Text Available With the purpose to help in the orthodontic treatment, the use of the osseointegrated implants have been shown an eficient form of intraoral anchorage, mainly in cases of adults pacients with missing posterior teeth or when they don't accept with the use of the extraoral appliance. The objective of this article is describe a brief review of the history of implants in orthodontics, remarking the main indications, types an dimension of implants, place of instalation, types of moviments, time of osseointegration and the advantages and disadvantages of the implants utilized as anchorage in orthodontics.

  15. Asymmetry a challenge for orthodontists

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    planes of space. A systematic approach to the identification of the cause of the asymmetry head precede the decision whether to correct or to camouflage. The definition of a specific treatment goal should be done only following an analysis of the likelihood that the force system necessary to perform...... the required tooth displacements can be generated. In order to control the interaction between the force systems developed in the three planes of space, the appliances should commonly be segmented. Anchorage problems can occasionally only be solved by means of skeletal anchorage....

  16. Topographic features around Zhongshan Station, southeast of Prydz Bay

    Institute of Scientific and Technical Information of China (English)

    FENG Shouzhen; XUE Zuo; CHI Wanqing

    2008-01-01

    Considering the complex topographic features of the southeast of Prydz Bay where China's Zhongshan Station is located, three types of geomorphologic units can be identified, i.e., submarine slopes, canyons, and terrains. The major topographic features in the study area are the submarine canyon and trough system outside the calving ice front of Dalk Glacier. A 3.8 km × 80 m fissure is found on the submarine terrain at Zhongshan Anchorage, which, once triggered by geological hazards such as earthquakes and ice falls, would be a threat to the usage and maintenance of the anchorage.

  17. Shear strengthening of full-scale RC T-beams using textile-reinforced mortar and textile-based anchors

    OpenAIRE

    Tetta, Z.C.; Koutas, L.N.; Bournas, D.A.

    2016-01-01

    This paper presents a study on the effectiveness of TRM jacketing in shear strengthening of full-scale reinforced concrete (RC) T-beams focussing on the behaviour of a novel end-anchorage system comprising textile-based anchors. The parameters examined in this study include: (a) the use of textile-based anchors as end-anchorage system of TRM U-jackets; (b) the number of TRM layers; (c) the textile properties (material, geometry); and (d) the strengthening system, namely textile-reinforced mor...

  18. SHEAR CARRYING CAPACITY OF SEGMENTAL CONCRETE BEAMS WITH DRAPED EXTERNAL TENDONS

    Science.gov (United States)

    Nguyen, Dinh Hung; Matsumoto, Koji; Watanabe, Ken; Hasegawa, Tsuyoshi; Niwa, Junichiro

    This study presents an investigation of the shear be havior of segmental concrete beams with draped external tendons. Deviator force and transfer mechanism of prestressing force from an anchorage that affect the shear failure mechanism have been examined base d on the results of experimental procedure and FEM with different location of deviator and inclined angle of draped tendons. The modified model proposed by authors has been extended for segmental concrete beam s with draped external tendons with considering the effect of deviator force and transfer mechanism of prestressing force from the anchorage. The results from the extended modified model for draped external tendons had a good agreement with experimental results.

  19. 241-U-701 new compressor building and instrument air piping analyses

    International Nuclear Information System (INIS)

    Building anchorage analysis is performed to qualify the design of the new compressor building foundation given in the ECN ''241-U-701 New Compressor Building.'' Recommendations for some changes in the ECN are made accordingly. Calculations show that the 6-in.-slab is capable of supporting the pipe supports, and that the building foundation, air compressor and dryer anchorage, and electric rack are adequate structurally. Analysis also shows that the instrument air piping and pipe supports for the compressed air system meet the applicable code requirements and are acceptable. The building is for the U-Farm instrument air systems

  20. MULTIPHASE BLASTING OF THE BRIDGE ACROSS THE DRENICA RIVER

    OpenAIRE

    Branko Božić

    1989-01-01

    The construction of new bridges on the sites of the existing ones require demolition of the old bridge. Due to closeness of newly erected bridge elements the fundations of old bridges are demolished by multiphase blasting process. The blasting of the piers and anchorages of the bridge across 'the Drenica river carrying the Balačevac—Goleš industrial railway was done in four phases. The piers and anchorages of a new bridge and its construction elements have been erected before (the paper is pu...

  1. Corticotomy-assisted retraction: An outcome assessment

    Directory of Open Access Journals (Sweden)

    S Vijayashri Sakthi

    2014-01-01

    Conclusion: The rate of retraction with study group was twice as faster when compared to the control group, accelerating during the first 2 months of retraction. There was better anchorage control with the undecorticated molar segment during the retraction period but was found to increase as time advanced.

  2. The measurement of un-bonded tendon loads in PCPV and primary containment buildings

    International Nuclear Information System (INIS)

    This paper describes work undertaken as part of a study conducted for the Licensees of all commercial nuclear generating stations in the United Kingdom. The scope included researching the records of prestressing tendon load measurements held by the Licensees which encompassed 18 prestressed concrete pressure vessels (PCPV) for gas cooled reactors and one primary containment for PWR; the historical record contains more than 300 reactor-years of data. The main purpose of the study was to assess the validity of specified calibration and measurement techniques used by the Licensees or their contractors to establish jacking and residual anchorage loads in the post construction period. This included existing lift-off measurement techniques such as feeler gauge insertion and displacement transducer systems allied to graphical analysis of jack load versus displacement to determine the residual anchorage load. The second stage was to assess the designer's assumptions regarding long term creep and relaxation effects in the light of all available load checks since construction to determine whether the original design was adversely affected as a result of the current assessment of tendon load distributions. The paper includes summaries of the results of the assessment of historical load check data, load measurement methods and derived residual anchorage loads. Conclusions are made regarding the validity of design assumptions for anchorage and residual tendon loads and their implications for future load measurements

  3. Surface slick trajectories and risk analysis to oil spill and its derivates, caused by vessel in the Vitoria Bay and Espirito Santo Bay; Analise da trajetoria e dos riscos do derrame de petroleo e seus derivados proveniente da area de fundeio dos portos situados nas baias de Vitoria e do Espirito Santo

    Energy Technology Data Exchange (ETDEWEB)

    Fontana, A.R. [Espirito Santo Univ., Vitoria, ES (Brazil). Programa de Pos-graduacao em Engenharia Ambiental]. E-mail: arfont@terra.com.br; Sarmento, R. [Espirito Santo Univ., Vitoria, ES (Brazil)]. E-mail: robsar@npd.ufes.br

    2003-07-01

    This report presents information of surface slick trajectories and risk analysis to oil spill, provoked by vessel in the Vitoria Bay and Espirito Santo Bay anchorage port area. The trajectory has been simulated by mathematical modeling surface spill trajectory, pushed by wind and tidal currents. Those information are a contribution to elaborate contingency plans to the ports activities in this region. (author)

  4. 78 FR 13207 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2013-02-26

    ... Sig.) THE WHITE HOUSE, February 22, 2013. [FR Doc. 2013-04641 Filed 2-25-13; 11:15 am] Billing code... Emergency With Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage... ] Notice of February 22, 2013 Continuation of the National Emergency With Respect to Cuba and of...

  5. 75 FR 8791 - Continuation of the National Emergency Relating to Cuba and of the Emergency Authority Relating...

    Science.gov (United States)

    2010-02-25

    ... transmitted to the Congress. (Presidential Sig.) THE WHITE HOUSE, February 23, 2010. [FR Doc. 2010-4107 Filed... Notice of February 23, 2010--Continuation of the National Emergency Relating to Cuba and of the Emergency... Emergency Relating to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage...

  6. 76 FR 11071 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2011-02-28

    ... Sig.) THE WHITE HOUSE, February 24, 2011. [FR Doc. 2011-4596 Filed 2-25-11; 11:15 am] Billing code... Emergency With Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage... ] Notice of February 24, 2011 Continuation of the National Emergency With Respect to Cuba and of...

  7. 77 FR 11377 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2012-02-24

    ... Sig.) THE WHITE HOUSE, February 23, 2012. [FR Doc. 2012-4614 Filed 2-23-12; 11:15 am] Billing code... With Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and..., 2012 Continuation of the National Emergency With Respect to Cuba and of the Emergency...

  8. Civic Cohesion, and Sanctuaries for Coming to Terms with Modernity

    DEFF Research Database (Denmark)

    Greve, Anni

    2006-01-01

    The city is a key location of the modern social world, a home of rootlessness and transient everyday encounters between individuals. This essay explores the idea of 'the sanctuary' as a way in which people look for anchorage, and create and re-create images of a society, to cope with and negotiat...

  9. 33 CFR 110.194a - Mobile Bay, Ala., and Mississippi Sound, Miss.

    Science.gov (United States)

    2010-07-01

    ... Sound, Miss. 110.194a Section 110.194a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Mississippi Sound, Miss. (a) The anchorage grounds. (1) The waters of lower Mobile Bay, near Cedar Point... south by latitude 30°20′00″, and on the west by longitude 88°06′00″. (2) The waters of Mississippi...

  10. 改良腭弓矫治后牙锁节对后牙功能恢复的影响%Influence of promote palatine arch treating buccal teeth lock on occlusion function recovery of buccal teeth

    Institute of Scientific and Technical Information of China (English)

    马宁; 孙应明; 白槐延

    2002-01-01

    @@ Background: Buccal teeth occlusion lock is a kind of common malocclusion malformation in orthodonic clinic. Traditional treatment to buccal teeth occlusion lock is interactive traction of upper and lower buccal teeth.This treatment had shortcoming such as insufficient anchorage and elongation of buccal teeth.We adopted promote fix palatine arch therapy, which recovery patients' occlusion function by clinical observation.

  11. Report of a Class I bimaxillary dental protrusion case with extraction of first premolars treated with Clarity™ SL MBT appliances

    OpenAIRE

    Hugo Trevisi; Renata Trevisi; Lars R Christensen

    2013-01-01

    Bimaxillary protrusion cases are common in orthodontic practice. For the best facial outcome, the biomechanics can often be challenging. A class I bimaxillary protrusion case is presented below illustrating the careful application of extractions and bracket prescription. The case highlights how self-ligating brackets and high precision bracket positioning can reduce the need for additional anchorage.

  12. 75 FR 54026 - Safety Zone; Red Bull Flugtag, Delaware River, Camden, NJ

    Science.gov (United States)

    2010-09-03

    ... Marina and South of the Benjamin Franklin Bridge. The safety zone will restrict vessel traffic from a... Delaware River in an area described as north of the Wiggins Park Marina and south of the Benjamin Franklin... vessel intending to transit East of Anchorage Area 13 in the Delaware River South of the...

  13. 29 CFR 1926.601 - Motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... employees to be carried. (9) Seat belts and anchorages meeting the requirements of 49 CFR part 571... 29 Labor 8 2010-07-01 2010-07-01 false Motor vehicles. 1926.601 Section 1926.601 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Motor Vehicles, Mechanized Equipment, and...

  14. A concrete balanced cantilever box girder bridge in the Netherlands with carbon fibre prestressing cables

    NARCIS (Netherlands)

    Hordijk, D.A.; Bruggeling, A.S.G.; Kaptijn, N.

    1998-01-01

    In the Netherlands a pilot project has started to recognize the possibilities of non-metallic materials for prestressing. This project will also serve to gather more knowledge regarding the properties of non-metallic wires, their anchorages and their application in large tendons. It is intended to a

  15. Un error en los calculos matematicos destroza el acelerador de particulas del CERN

    CERN Document Server

    Cernuda, Olalla

    2007-01-01

    The most famous particle accelerator in the world, who is at CERN, has suffered a catastrophic damage after a great explosion took place in its depths. This explosion has an absolutely scientific explanation: a mathematical mistake in the design of the anchorages of great magnets. (1 page)

  16. 76 FR 55325 - Approval and Promulgation of State Implementation Plans: Alaska

    Science.gov (United States)

    2011-09-07

    ... of Subjects in 40 CFR Part 52 Environmental protection, Air pollution control, Carbon monoxide..., 1978. The Municipality of Anchorage prepared a plan to attain the CO National Ambient Air Quality... (67 FR 58711). \\1\\ The national 8-hour CO ambient standard is attained when the highest 8-hour...

  17. 77 FR 1414 - Approval and Promulgation of State Implementation Plans: Alaska

    Science.gov (United States)

    2012-01-10

    ... Environmental protection, Air pollution control, Carbon monoxide, Incorporation by reference, Intergovernmental... Anchorage Carbon Monoxide Maintenance Plan (Volume II Sections II, III.A and III.B of the State Air Quality... maintenance of the National Ambient Air Quality Standards (NAAQS), or any other CAA requirements. See...

  18. 33 CFR 110.156 - Randall Bay, Freeport, Long Island, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Randall Bay, Freeport, Long Island, N.Y. 110.156 Section 110.156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND....Y. (a) The anchorage grounds. Southward of a line 312 feet south of and parallel to the south...

  19. 75 FR 53333 - Notice of Filing of Plats of Survey, Alaska

    Science.gov (United States)

    2010-08-31

    .... Stephen B. Hamrick, Chief Cadastral Surveyor. BILLING CODE 4310-JA-P ... Bureau of Land Management Notice of Filing of Plats of Survey, Alaska AGENCY: Bureau of Land Management... Office, Bureau of Land Management, Anchorage, Alaska, must receive comments on or before September...

  20. 78 FR 59715 - Outer Continental Shelf (OCS), Alaska OCS Region, Chukchi Sea Planning Area, Proposed Oil and Gas...

    Science.gov (United States)

    2013-09-27

    ... for Exclusion Areas, and Other Comments Interested parties who are requesting area(s) for inclusion in..., Anchorage, Alaska 99503-5823. Requests for proposed exclusion areas or general proposed inclusion areas... inclusion or exclusion of acreage, temporal deferrals, and/or mitigation from the Five Year Program...

  1. 78 FR 12794 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-02-25

    .... Corporation (IBC), Hostess Brands, Inc. 82,165A Interstate Brands Montgomery, AL..... November 19, 2011. Corporation (IBC), Hostess Brands, Inc. 82,165AA Interstate Brands Rochester, NH...... November 19, 2011. Corporation (IBC), Hostess Brands, Inc. 82,165B Interstate Brands Anchorage, AK...... November 19,...

  2. A simple approach to cancer therapy afforded by multivalent pseudopeptides that target cell-surface nucleoproteins

    NARCIS (Netherlands)

    Destouches, D.; Page, N.; Hamma-Kourbali, Y.; Machi, V.; Chaloin, O.; Frechault, S.; Birmpas, C.; Katsoris, P.; Beyrath, J.D.; Albanese, P.; Maurer, M.; Carpentier, G.; Strub, J.M.; Dorsselaer, A. van; Muller, S.; Bagnard, D.; Briand, J.P.; Courty, J.

    2011-01-01

    Recent studies have implicated the involvement of cell surface forms of nucleolin in tumor growth. In this study, we investigated whether a synthetic ligand of cell-surface nucleolin known as N6L could exert antitumor activity. We found that N6L inhibits the anchorage-dependent and independent growt

  3. The politics of symmetry

    NARCIS (Netherlands)

    Pels, D.L.

    1996-01-01

    While symmetry and impartiality have become ruling principles in S&TS, defining its core ideal of a 'value-free relativism', their philosophical anchorage has attracted much less discussion than the issue or:how far their jurisdiction can be extended or generalized. This paper seeks to argue that sy

  4. 78 FR 55061 - North Pacific Fishery Management Council; Public Meetings

    Science.gov (United States)

    2013-09-09

    ... the Magnuson- Stevens Act section 302(g)(1)(e), and the National Standard 2 guidelines (78 FR 43066). The peer review process is also deemed to satisfy the requirements of the Information Quality Act... executive sessions. ADDRESSES: The meetings will be held on Hilton Hotel, 500 West 3rd Avenue, Anchorage,...

  5. 33 CFR 110.140 - Buzzards Bay, Nantucket Sound, and adjacent waters, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buzzards Bay, Nantucket Sound, and adjacent waters, Mass. 110.140 Section 110.140 Navigation and Navigable Waters COAST GUARD..., Nantucket Sound, and adjacent waters, Mass. (a) New Bedford Outer Harbor—(1) Anchorage A. West of...

  6. Reconfiguring a Campus--Fast.

    Science.gov (United States)

    Hignite, Karla

    2003-01-01

    Describes the first phase of a master plan to expand the University of Alaska-Anchorage by purchasing a shopping mall and reconfiguring campus services to take advantage of the additional space. The master plan calls for eventually moving administration to the periphery of the campus and migrating academic programs to the campus center. (SLD)

  7. Development of Mechanical Anchor for CFRP Tendons Using Integrated Sleeve

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Bennitz, Anders; Täljsten, Björn;

    2010-01-01

    A durable and very efficient external strengthening system is achieved if steel tendons for post-tensioning applications can be replaced with CFRP (Carbon Fibre Reinforced Polymer) tendons and if reliable anchorage systems are developed,. This paper presents a newly developed and simple-to-use two...

  8. On the plastic behaviour of multi directional epoxy-bolted CFRP laminates

    DEFF Research Database (Denmark)

    Jensen, Aage; Poulsen, Ervin

    2004-01-01

    The second generation of CFRP laminate has recently been developed. It is a multi directional CFRP laminate, i.e. a laminate with carbon fibres having several directions other than the first generation. The paper describes the laboratory tests carried out in order to develop anchorage devices...

  9. 76 FR 82114 - Amendment of VOR Federal Airways V-320 and V-440; Alaska

    Science.gov (United States)

    2011-12-30

    ... and efficient management of Instrument Flight Rules (IFR) operations within the National Airspace... Anchorage VOR navigation aid (76 FR 68674). Interested parties were invited to participate in this... (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a regulatory evaluation...

  10. 33 CFR 110.195 - Mississippi River below Baton Rouge, LA, including South and Southwest Passes.

    Science.gov (United States)

    2010-07-01

    ... cargos of particular hazard as defined in 33 CFR 126.10 or cargos of petroleum products in bulk may not... citations affecting § 110.195, see the List of CFR Sections Affected, which appears in the Finding Aids...) Belle Chasse Anchorage. An area 2.1 miles in length along the right descending bank of the...

  11. 50 CFR 27.92 - Private structures.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Private structures. 27.92 Section 27.92... NATIONAL WILDLIFE REFUGE SYSTEM PROHIBITED ACTS Other Disturbing Violations § 27.92 Private structures. No..., pier, dock, fence, wall, pile, anchorage, or other structure or obstruction in any national...

  12. The life times of polymer composites in construction

    Science.gov (United States)

    Meier, Urs

    2016-05-01

    This paper discusses examples that prove the long-term reliability of Fiber Reinforced Polymers (FRP) under extreme loading conditions and outdoor weathering. Results of polymer/steel-composite anchorage systems, Glass Fiber Reinforced Polymer (GFRP) plates and shells, GFRP box girders, Carbon Fiber Reinforced Polymer (CFRP) post-tensioning tendons and CFRP stays are going to be presented.

  13. 75 FR 7517 - Notice of Intent To Prepare an Amendment to the Ring of Fire Resource Management Plan for the...

    Science.gov (United States)

    2010-02-19

    ... administrative site and Special Recreation Management Area in Anchorage, Alaska. The site is currently managed... rights will be protected throughout the planning area; 5. Established and current agreements will remain... Bureau of Land Management Notice of Intent To Prepare an Amendment to the Ring of Fire...

  14. Hooked… make it simple and easy

    Directory of Open Access Journals (Sweden)

    Sheetal Potnis

    2014-01-01

    Full Text Available Temporary anchorage devices (TADs have solved a lot of orthodontic treatment dilemmas. Attachment of elastomers to these TADs is sometimes difficult, especially with embedded microimplants like in the infrazygomatic area. Here, a simple modification has been made in the attachment of elastomeric chain to ligature wire for ease of replacing the elastomeric chain.

  15. 33 CFR 110.188 - Atlantic Ocean off Miami and Miami Beach, Fla.

    Science.gov (United States)

    2010-07-01

    ... Miami Beach, Fla. (a) The anchorage grounds. The area to the eastward of a line bearing 12° (N. 12° E.) through a point X, which is 11/2 nautical miles due east of the intersection of the Miami Beach shore line... Miami Beach, Fla. 110.188 Section 110.188 Navigation and Navigable Waters COAST GUARD, DEPARTMENT...

  16. Encoding the Shipping Crisis

    Institute of Scientific and Technical Information of China (English)

    Xue Lina; Lin Lin; Wang Siyuan

    2009-01-01

    @@ According to the statistics from Frech shipping advisory bod-ies,till December 21,2008,165 container ships were idle,leav-ing the fees,such as anchorage fees,ship maintaining fee,crev resettlement fee and repaying loans for ship-buying,an-noying the ship-owners.

  17. 32 CFR Appendix D to Part 45 - State Directors of Veterans Affairs

    Science.gov (United States)

    2010-07-01

    ..., MILITARY AND CIVILIAN CERTIFICATE OF RELEASE OR DISCHARGE FROM ACTIVE DUTY (DD FORM 214/5 SERIES) Pt. 45..., Department of Military & Veterans Affairs, 3601 C Street, suite 620, Anchorage, AK 99503. American Samoa..., Johnston, IA 50131-1902. Kansas Executive Director, Kansas Veterans Commission, Jayhawk Tower, suite...

  18. Strategies for Successful Retention of Alaska Native and American Indian Study Participants

    Science.gov (United States)

    Redwood, Diana; Leston, Jessica; Asay, Elvin; Ferucci, Elizabeth; Etzel, Ruth; Lanier, Anne P.

    2011-01-01

    This paper reports the strategies used to track and follow 3,828 Alaska Native and American Indian study participants in the city of Anchorage and more rural areas of Alaska and provides characteristics of respondents and non-respondents. Over 88% were successfully followed-up, with 49% of respondents completed in three or fewer attempts.…

  19. It's Not a Matter of Time: Highlights from the 2011 Competency-Based Summit

    Science.gov (United States)

    Sturgis, Chris; Patrick, Susan; Pittenger, Linda

    2011-01-01

    From Anchorage, Alaska, to Orlando, Florida, and from Gray, Maine, to Yuma, Arizona, one hundred competency-based innovators gathered at the Competency-Based Learning Summit in March 2011. Sponsored by the Council of Chief State School Officers (CCSSO) and the International Association for K-12 Online Learning (iNACOL), the Summit was developed in…

  20. 77 FR 303 - Sunshine Act Notice

    Science.gov (United States)

    2012-01-04

    ... session on Tuesday, 24 January 2012, from 10:30 to 12:30 p.m. PLACE: Sheraton Anchorage Hotel, 401 E. 6th... agency processes, personnel, and the budget of the Commission. All other portions of the meeting will...