WorldWideScience

Sample records for anchorages

  1. Anchorage Areas

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — An anchorage area is a place where boats and ships can safely drop anchor. These areas are created in navigable waterways when ships and vessels require them for...

  2. Bone anchorage: When and why?

    OpenAIRE

    Ahmet Nejat Erverdi

    2015-01-01

    Anchorage is the most important concept in biomechanics of orthodontics. In contemporary orthodontics, bone anchorage is a magic tool, which decreased the indication for extraoral appliances greatly and at the same time achieving stationary anchorage became possible. However, the indication for bone anchorage has to be clarified carefully. Skeletal open-bite treatment, effective molar distalization, Class III treatment by using chin anchorage, and space closure in severe minimal anchorage cas...

  3. Bone anchorage: When and why?

    Directory of Open Access Journals (Sweden)

    Ahmet Nejat Erverdi

    2015-01-01

    Full Text Available Anchorage is the most important concept in biomechanics of orthodontics. In contemporary orthodontics, bone anchorage is a magic tool, which decreased the indication for extraoral appliances greatly and at the same time achieving stationary anchorage became possible. However, the indication for bone anchorage has to be clarified carefully. Skeletal open-bite treatment, effective molar distalization, Class III treatment by using chin anchorage, and space closure in severe minimal anchorage cases are some examples for bone anchorage supported orthodontic treatment. Here, we discussed three necessary usages of bone anchorage for different treatment modalities.

  4. TERRAIN, Anchorage, Alaska

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Anchorage AOI consists of seven areas. These areas were to be collected to the 'highest' accuracy requirement. Ground Control is collected throughout the AOI for...

  5. Friction and anchorage loading revisited.

    Science.gov (United States)

    Dholakia, Kartik D

    2012-01-01

    Contemporary concepts of sliding mechanics explain that friction is inevitable. To overcome this frictional resistance, excess force is required to retract the tooth along the archwire (ie, individual retraction of canines, en masse retraction of anterior teeth), in addition to the amount of force required for tooth movement. The anterior tooth retraction force, in addition to excess force (to overcome friction), produces reciprocal protraction force on molars, thereby leading to increased anchorage loading. However, this traditional concept was challenged in recent literature, which was based on the finite element model, but did not bear correlation to the clinical scenario. This article will reinforce the fact that clinically, friction increases anchorage loading in all three planes of space, considering the fact that tooth movement is a quasistatic process rather than a purely continuous or static one, and that conventional ways of determining the effects of static or dynamic friction on anchorage load cannot be applied to clinical situations (which consist of anatomical resistance units and a complex muscular force system). The article does not aim to quantify friction and its effect on the amount of anchorage load. Rather, a new perspective regarding the role of various additional factors (which is not explained by contemporary concept) that may influence friction and anchorage loading is provided..

  6. 29 CFR 1926.755 - Column anchorage.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Column anchorage. 1926.755 Section 1926.755 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Steel Erection § 1926.755 Column anchorage. (a) General requirements for erection stability. (1) All columns shall be anchored by a minimum of 4 anchor...

  7. 78 FR 11099 - Safety Zone Within the Lower Portion of Anchorage #9, Mantua Creek Anchorage; Paulsboro, NJ

    Science.gov (United States)

    2013-02-15

    ... 1625-AA00 Safety Zone Within the Lower Portion of Anchorage 9, Mantua Creek Anchorage; Paulsboro, NJ... temporary safety zone around the southern one-third of Anchorage 9 (Mantua Creek Anchorage), below position 39[deg] 51.573 N-075[deg] 13.557 W due to dredging operations. The Dredge Florida will be working...

  8. Performance of Sequoyah Containment Anchorage System

    International Nuclear Information System (INIS)

    Fanous, F.; Greimann, L.; Wassef, W.; Bluhm, D.

    1993-01-01

    Deformation of a steel containment anchorage system during a severe accident may result in a leakage path at the containment boundaries. Current design criteria are based on either ductile or brittle failure modes of headed bolts that do not account for factors such as cracking of the containment basemat or deformation of the anchor bolt that may affect the behavior of the containment anchorage system. The purpose of this study was to investigate the performance of a typical ice condenser containment's anchorage system. This was accomplished by analyzing the Sequoyah Containment Anchorage System. Based on a strength of materials approach and assuming that the anchor bolts are resisting the uplift caused by the internal pressure, one can estimate that the failure of the anchor bolts would occur at a containment pressure of 79 psig. To verify these results and to calibrate the strength of materials equation, the Sequoyah containment anchorage system was analyzed with the ABAQUS program using a three-dimensional, finite-element model. The model included portions of the steel containment building, shield building, anchor bolt assembly, reinforced concrete mat and soil foundation material

  9. PEM Anchorage on Titanium Using Catechol Grafting

    Science.gov (United States)

    Marie, Hélène; Barrere, Amélie; Schoentstein, Frédérique; Chavanne, Marie-Hélène; Grosgogeat, Brigitte; Mora, Laurence

    2012-01-01

    Background This study deals with the anchorage of polyelectrolyte films onto titanium surfaces via a cathecol-based linker for biomedical applications. Methodology The following study uses a molecule functionalized with a catechol and a carboxylic acid: 3-(3,4-dihydroxyphenyl)propanoic acid. This molecule is anchored to the TiO2 substrate via the catechol while the carboxylic acid reacts with polymers bearing amine groups. By providing a film anchorage of chemisorption type, it makes possible to deposit polyelectrolytes on the surface of titanium. Principal Findings Infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), contact angle and atomic force microscopy (AFM) measurements show that the different steps of grafting have been successfully performed. Conclusions This method based on catechol anchorage of polyelectrolytes open a window towards large possibilities of clinical applications. PMID:23226262

  10. 75 FR 76275 - Anchorage Regulations; Long Island Sound

    Science.gov (United States)

    2010-12-08

    ...-AA01 Anchorage Regulations; Long Island Sound AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: In this rule the Coast Guard establishes seven anchorage grounds in Long Island Sound. These anchorages... Long Island Sound or awaiting entry to a port or facility in New York and Connecticut. DATES: This rule...

  11. Paradigm shifts in orthodontic treatment with mini-implant anchorage

    Directory of Open Access Journals (Sweden)

    Johnny Joung-Lin Liaw

    2015-01-01

    Full Text Available After the applications of mini-implant anchorage, the envelope of orthodontic treatment was expanded and some treatment modes were changed because of more predictable tooth movement with empowered anchorage. The author tried to share his experience of TADs applications for clarifying the paradigm shifts of orthodontic treatment assisted with the mini-implant anchorage.

  12. Explaining the democratic anchorage of governance networks

    DEFF Research Database (Denmark)

    Skelcher, Chris; Klijn, Erik-Hans; Kübler, Daniel

    2011-01-01

    Advances in understanding the democratic anchorage of governance networks require carefully designed and contextually grounded empirical analysis that take into account contextual factors. The article uses a conjectural framework to study the impact of the national democratic milieu on the relati...

  13. Seismic verification of nuclear plant equipment anchorage

    International Nuclear Information System (INIS)

    Lepiece, M.; Van Vyve, J.

    1991-01-01

    More than 60% of the electrical power of Belgium is generated by seven PWR nuclear power plants. For three of them, the electro-mechanical equipment had to be reassessed after ten years of operation, because the seismic requirements were upgraded from 0.1 g to 0.17 g free field ground acceleration. The seismic requalification of the active equipment was a critical problem as the classical methods were too conservative. The approach based on the use of the past experience on the seismic behavior of nonnuclear equipment, chosen and developed by the SQUG, had to be transposed to the Belgian N.P.P. The decision of the accept-ability of equipment relies heavily on the aseismatic capacity of anchorage. The Electrical Power Research Institute (EPRI) developed the procedure and guideline for the demonstration of the aseismatic adequacy of equipment anchorage in a cost-effective and consistent manner, to support the decision by Seismic Review Team. The field inspection procedure to identify the type of fasteners and detect their possible defects and the verification procedure developed to calculate the aseismatic capacity of equipment anchorage on the strength of fasteners, the aseismatic capacity of anchorage and the comparison of the capacity with the demand are reported. (K.I.)

  14. Orthodontic Anchorage Implants: State-of-the-art

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    The limits of an orthodontic treatment are often set by the lack of suitable anchorage. The mini-implant is used where conventional anchorage cannot be applied and not as a replacement for conventional anchorage. In patients with lack of teeth and reduced periodontium, skeletal anchorage allows...... the optimal positioning of the teeth following rehabilitation. Patients with need for inconsistent tooth movements, borderline surgical cases, can benefit from the use of the mini-implant and regeneration of alveolar process by tooth movement in edentulous molar regions and using mini-implants as anchorage...... will improve the reconstruction possibilities. The mini-implant has widened the orthodontic possibilities....

  15. Procedures adopted by orthodontists for space closure and anchorage control

    Directory of Open Access Journals (Sweden)

    André da Costa Monini

    2013-12-01

    Full Text Available OBJECTIVE: The aim of this study was to identify the procedures adopted by Brazilian orthodontists in the following situations: extraction space closure, anchorage control in case of necessary anchorage for group A and frequency of skeletal anchorage use, especially in the upper jaw. METHOD: A questionnaire was sent to the e-mail address of all dentists registered in the Brazilian Federal Council of Dentistry. RESULTS: The results showed that most Brazilian orthodontists usually perform extraction space closure by means of sliding mechanics. The use of palatal bar, inclusion of second molars in the archwire and space closure performed in two phases are the most used techniques for anchorage control in the upper jaw. The skeletal anchorage is referenced by 36.5% of specialists as a routine practice for the upper jaw anchorage. CONCLUSIONS: There is a wide variety of procedures adopted by Brazilian orthodontists for orthodontic space closure and anchorage control.

  16. Procedures adopted by orthodontists for space closure and anchorage control.

    Science.gov (United States)

    Monini, André da Costa; Gandini Júnior, Luiz Gonzaga; dos Santos-Pinto, Ary; Maia, Luiz Guilherme Martins; Rodrigues, Willian Caetano

    2013-01-01

    The aim of this study was to identify the procedures adopted by Brazilian orthodontists in the following situations: extraction space closure, anchorage control in case of necessary anchorage for group A and frequency of skeletal anchorage use, especially in the upper jaw. A questionnaire was sent to the e-mail address of all dentists registered in the Brazilian Federal Council of Dentistry. The results showed that most Brazilian orthodontists usually perform extraction space closure by means of sliding mechanics. The use of palatal bar, inclusion of second molars in the archwire and space closure performed in two phases are the most used techniques for anchorage control in the upper jaw. The skeletal anchorage is referenced by 36.5% of specialists as a routine practice for the upper arch anchorage. There is a wide variety of procedures adopted by Brazilian orthodontists for orthodontic space closure and anchorage control.

  17. Is skeletal anchorage changing the limit of orthodontics?

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    and can be loaded immediately. The course will be addressed the following topics: Are the mini-implants replacing conventional anchorage? Why are orthodontic mini-implants necessary? The development of the skeletal anchorage systems The biological basis for the skeletal anchorage systems......The limits for orthodontic treatment are often set by the lack of suitable anchorage. The mini-implant is used where conventional anchorage cannot be applied; not as a replacement for conventional anchorage. In patients with lack of teeth and reduced periodontium, skeletal anchorage allows...... for the optimal positioning of the teeth before rehabilitation. Patients, with need for inconsistent tooth movements as displacement of all teeth in the same direction or asymmetric displacements, can be treated with the mini-implants. Borderline surgical cases can benefit from the use of mini-implants...

  18. Anchorage Dependent Cells Attached to a Polymer

    Science.gov (United States)

    2004-01-01

    Biomedical research offers hope for a variety of medical problems, from diabetes to the replacement of damaged bone and tissues. Bioreactors, which are used to grow cells and tissue cultures, play a major role in such research and production efforts. Anchorage dependent cells on STS-95 will be grown on beads similar to these cells produced during previous investigations. Recombinant proteins may offer the possibility of reducing or eliminating transplant rejections. Research by Synthecon, Inc. using the BioDyn Bioreactor will focus on the preliminary process for growing a proprietary recombinant protein that can decrease rejection of transplanted tissue. The cells producing this protein are anchorage dependent, meaning that they must attach to something to grow. These cells will be cultured in the bioreactor in a medium containing polymer microbeads. Synthecon hopes that the data from this mission will lead to the development of a commercial protein that will aid in prevention of transplant rejection.

  19. The use of microimplants in orthodontic anchorage.

    Science.gov (United States)

    Chen, Chung-Ho; Chang, Chao-San; Hsieh, Chi-Hsin; Tseng, Yu-Chuan; Shen, Yee-Shyong; Huang, I-Yueh; Yang, Chia-Fu; Chen, Chun-Ming

    2006-08-01

    Various types of temporary implants have been introduced to serve as orthodontic anchorage. The hypothesis of this study is that microimplants of 1.2 mm diameter can be used as orthodontic anchors, and that their success is related to their length. The aim of this study is to determine the incidence of anchor retention after orthodontic force application for moving teeth, and to determine the relationship of microimplant length to retention rate. Fifty-nine microimplants (diameter: 1.2 mm) were placed in 29 patients as orthodontic anchorages. After 2 weeks of microimplant placement, a force of 100 to 200 g was loaded with an elastometric chain or NiTi coil spring. Risk factors were characterized as to why a microimplant may fail, and Fisher's exact test was used for statistical analysis. Nine microimplants were removed and the overall success rate was 84.7%. Exploring the causes for failure, we found significant differences between the length of microimplants and success rate; 6 mm was 72.2% and 8 mm was 90.2%. The results suggest that microimplants are suited as an alternative orthodontic anchorage. We recommend that 8-mm microimplants are preferable to 6-mm.

  20. 33 CFR 110.189a - Key West Harbor, Key West, Fla., naval explosives anchorage area.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Key West Harbor, Key West, Fla..., DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.189a Key West Harbor, Key West, Fla., naval explosives anchorage area. (a) The anchorage ground. A circular area with its...

  1. Shear and anchorage behaviour of fire exposed hollow core slabs

    OpenAIRE

    Fellinger, J.H.H.; Stark, J.; Walraven, J.C.

    2005-01-01

    The fire resistance of hollow core slabs is currently assessed considering flexural failure only. However, fire tests showed that shear or anchorage failure can also govern the load bearing behaviour. As the shear and anchorage capacity of these slabs rely on the tensile strength of the concrete, the load bearing capacity with respect to these failure modes decreases dramatically during fire due to the impact of thermal stresses. This paper presents a FE model for the shear and anchorage beha...

  2. Procedures adopted by orthodontists for space closure and anchorage control

    OpenAIRE

    Monini,André da Costa; Gandini Júnior,Luiz Gonzaga; Santos-Pinto,Ary dos; Maia,Luiz Guilherme Martins; Rodrigues,Willian Caetano

    2013-01-01

    OBJECTIVE: The aim of this study was to identify the procedures adopted by Brazilian orthodontists in the following situations: extraction space closure, anchorage control in case of necessary anchorage for group A and frequency of skeletal anchorage use, especially in the upper jaw. METHOD: A questionnaire was sent to the e-mail address of all dentists registered in the Brazilian Federal Council of Dentistry. RESULTS: The results showed that most Brazilian orthodontists usually perform extra...

  3. Cell cycle control by components of cell anchorage

    OpenAIRE

    Gad, Annica

    2005-01-01

    Extracellular factors, such as growth factors and cell anchorage to the extracellular matrix, control when and where cells may proliferate. This control is abolished when a normal cell transforms into a tumour cell. The control of cell proliferation by cell anchorage was elusive and less well studied than the control by growth factors. Therefore, we aimed to clarify at what points in the cell cycle and through which molecular mechanisms cell anchorage controls cell cycle pro...

  4. Analysis of post-tensioned girder anchorage zones

    Science.gov (United States)

    Stone, W. C.; Breen, J. E.

    1981-06-01

    Several large thin-webbed box girders, with post-tensioned anchorage zones experienced large cracks along the tendon path in the anchorage zones at the design stressing load. Cracking provides a path for penetration of moisture and salts and thus presents a potential corrosion and frost damage threat. Such cracking negates the use of prestressed concretes. An extensive literature review which documents the state of the art in anchorage zone analysis behavior, and design recommendations is summarized. The general utilization of a three dimensional finite element program, PUZGAP3D, for analysis of the complex anchorage zone region is outlined. The program was used to study straight and curved tendon paths.

  5. Orthodontic treatment with skeletal anchorage system

    Directory of Open Access Journals (Sweden)

    Arya Brahmanta

    2011-06-01

    Full Text Available Background: Correction of class I malocclusion with bimaxillary dental protrusion and unilateral free end right upper ridge in adult patient is one of difficult biomechanical case in orthodontics. Due to this case that needs proper anchorage for upper incisor retraction with missing teeth in the right posterior segment. Purpose: The aim of this study to find an effective therapy for correction of bimaxillary protrusion with unilateral free and ridge. Case: A female patient, 36 year old complaining for the difficulty of lip closure due to severe bimaxillary protrusion with incompetence lip. Case management: Firstly correction of the maxillary and mandibular incisor proclination were done by extraction of the mandibular first premolar, the maxillary second premolar on left side and finally placement of miniplates implant in the zygomatic process on right side as an absolut anchorage. Conclusion: Skeletal anchorage system (SAS can be considered as an effective therapy for corection of bimaxillary protrusion with unilateral free end ridge.Latar belakang: Koreksi dari maloklusi klas I dari penderita dewasa yang disertai protrusi bimaksiler dengan kehilangan gigi posterior pada regio kanan atas merupakan salah satu kasus sulit untuk dikerjakan terutama berhubungan dengan biomekanik pergerakan giginya dalam perawatan ortodonti. Tujuan: Tujuan dari penulisan artikel ini adalah untuk menemukan terapi yang efektif untuk perbaikan protrusi bimaksiler dan kehilangan gigi posterior pada satu sisi. Kasus: Seorang penderita wanita usia 35 tahun datang dengan keluhan utama kesulitan untuk menutup mulut oleh karena gigi rahang atas dan rahang bawahnya maju dan bibirnya tidak kompeten. Tatalaksana kasus: Koreksi pada gigi insisivus rahang atas dan insisivus rahang bawah yang protrusi dilakukan dengan melakukan pencabutan terlebih dahulu pada gigi premolar pertama dirahang bawah sisi kanan dan sisi kiri serta pencabutan pada gigi premolar kedua di rahang atas sisi

  6. Anchorage loss--a multifactorial response.

    Science.gov (United States)

    Geron, Silvia; Shpack, Nir; Kandos, Samouil; Davidovitch, Moshe; Vardimon, Alexander D

    2003-12-01

    Anchorage loss (AL) is a potential side effect of orthodontic mechanotherapy. In the present study, it is defined as the amount of mesial movement of the upper first permanent molar during premolar extraction space closure. In addition, AL is described as a multifactorial response in relation to the extraction site, appliance type, age, crowding, and overjet. For this study, 87 university clinic and private practice subjects, who were defined as maximum anchorage cases and had undergone bilateral maxillary premolar extractions, were divided into four groups according to extraction site (first vs second premolars), mechanics (lingual vs labial edgewise appliances), and age (adolescents vs adults). Overjet and crowding were examined from the overall sample. Data were collected from serial lateral cephalograms and dental casts. The results showed that as the severity of dental crowding increased, AL significantly decreased (r = -0.66, P = .001). Labial edgewise appliances demonstrated a significantly greater AL than did lingual edgewise appliances (1.15 +/- 2.06 mm, P extractions (0.51 +/- 1.33 mm). Overjet was weakly correlated to AL. These results suggest that AL is a multifactorial response and that the five examined factors can be divided into primary (crowding, mechanics) and secondary factors (age, extraction site, overjet), in declining order of importance.

  7. Anchorage strategies in geriatric hip fracture management

    Directory of Open Access Journals (Sweden)

    Knobe Matthias

    2016-12-01

    Full Text Available There is an enormous humanitarian and socioeconomic need to improve the quality and effectiveness of care for patients with hip fracture. To reduce mechanical complications in the osteosynthesis of proximal femoral fractures, improved fixation techniques have been developed including blade or screw-anchor devices, locked minimally invasive or cement augmentation strategies. However, despite numerous innovations and advances regarding implant design and surgical techniques, systemic and mechanical complication rates remain high. Treatment success depends on secure implant fixation in often-osteoporotic bone as well as on patient-specific factors (fracture stability, bone quality, comorbidity, and gender and surgeon-related factors (experience, correct reduction, and optimal screw placement in the head/neck fragment. For fracture fixation, the anchorage of the lag screw within the femoral head plays a crucial role depending on the implant’s design. Meta-analyses and randomized controlled studies demonstrate that there is a strong trend towards arthroplasty treating geriatric femoral neck fractures. However, for young adults as well as older patients with less compromised bone quality, or in undisplaced fractures, head-preserving therapy is preferred as it is less invasive and associated with good functional results. This review summarizes the evidence for the internal fixation of femoral neck fractures and trochanteric femoral fractures in elderly patients. In addition, biomechanical considerations regarding implant anchorage in the femoral head including rotation, migration, and femoral neck shortening are made. Finally, cement augmentation strategies for hip fracture implants are evaluated critically.

  8. Mechanical anchorage of FRP tendons – A literature review

    DEFF Research Database (Denmark)

    Schmidt, Jacob W.; Bennitz, Anders; Täljsten, Björn

    2012-01-01

    anchorage systems for use with Aramid, Glass and Carbon FRP tendons have been proposed over the last two decades. Each system is usually tailored to a particular type of tendon. This paper presents a brief overview of bonded anchorage applications while the primary literature review discusses three methods...

  9. Application and Curative Effect of Micro-implant Anchorage in ...

    African Journals Online (AJOL)

    The clinical application and efficacy observation of micro - implant anchorages have become a new research hot spot in the Department of. Stomatology. Instead of taking teeth as the basis, as was previously the case, this new anchorage exerts the counteracting force of orthodontics on the jaw, thus completely avoiding the.

  10. Shear and anchorage behaviour of fire exposed hollow core slabs

    NARCIS (Netherlands)

    Fellinger, J.H.H.; Stark, J.; Walraven, J.C.

    2005-01-01

    The fire resistance of hollow core slabs is currently assessed considering flexural failure only. However, fire tests showed that shear or anchorage failure can also govern the load bearing behaviour. As the shear and anchorage capacity of these slabs rely on the tensile strength of the concrete,

  11. 77 FR 60081 - Anchorages; Captain of the Port Puget Sound Zone, WA

    Science.gov (United States)

    2012-10-02

    ..., Cap Sante Tug and Barge General Anchorage, and Hat Island Tug and Barge General Anchorage. 2... area with a radius of 600 yards, having its center at 48 31'09'' N, 122 34'55'' W. (11) Cap Sante Tug and Barge General Anchorage. The Cap Sante Tug and Barge General Anchorage includes all waters...

  12. The use of miniature implants as orthodontic anchorage in dogs

    OpenAIRE

    Toru, DEGUCHI; Ryuzo, KANOMI; Lawerence, GARETTO P.; Eugene, ROBERTS W.; Teruko, TAKANO; Department of Orthodontics, Okayama University Graduate School of Medicine and Dentistry; Kanomi Dental Clinic; Department of Oral Facial Development, Indiana University School of Dentistry; Department of Oral Facial Development, Indiana University School of Dentistry; Department of Orthodontics, Okayama University Graduate School of Medicine and Dentistry

    2002-01-01

    In the past decade, there have been many attempts to use implants as anchorage devices. Unfortunately, previous reports limit the use of these implants for anchorage because of their large size. Clinically, in cases such as intrusion of molars are necessary, small implants placed between the roots of teeth would be a great benefit for the orthodontist. The objective of this study was to histomorphometrically (static) analyze the use of miniature implants. A total of 20 miniature implants (1.0...

  13. A comparison of miniplates and teeth for orthodontic anchorage.

    Science.gov (United States)

    Kim, Soojin; Herring, Susan; Wang, I-Chung; Alcalde, Rafael; Mak, Victor; Fu, Isaac; Huang, Greg

    2008-02-01

    In this study, we investigated orthodontic space closure of premolar extraction sites with miniplate anchorage compared with conventional tooth-borne anchorage in 8 adult beagle dogs. A split-mouth design with all 4 quadrants was used. Four premolars were extracted to create adequate space for premolar retraction. Retraction was performed with nickel-titanium coil springs. In the control side, the premolars were retracted against other teeth, and, in the experimental side, the premolars were retracted against miniplates. Each quadrant received 2 additional bone screws as bone markers for cephalometric superimposition. Lateral cephalograms were taken at initial activation, 6 weeks, and 12 weeks. Three parameters were measured and evaluated: linear space closure, angular tipping, and amount of anchorage slippage. Overall, the miniplates had a high success rate of 93.8% (15 of 16) during the 12-week period of orthodontic loading. Similar amounts of space closure were observed in the control and the experimental sites. A statistically significant difference was observed for the amounts of tipping and anchorage slippage of miniplates vs tooth-borne anchorage. In the maxilla, the mean miniplate tipping was 0.1 degrees , whereas mean tipping of the anchor teeth was 9 degrees (P = .01). In the mandible, the miniplates tipped an average of 3.4 degrees , whereas the mean tipping of the anchor teeth was 13.3 degrees (P = .02). In the maxilla, the miniplates had 1% anchorage loss, whereas the tooth anchors had 37.1% anchorage loss (P = .001). In the mandible, the miniplates had a mean anchorage loss of 4.5%, whereas the tooth anchors had a mean anchorage loss of 31.1% (P = .001). Although the total amount of space closure was similar in both the control and the experimental groups, the mechanism of space closure was different. In the control group, slippage of the anchor teeth accounted for approximately a third of the space closure. In the experimental group, the miniplates

  14. Stability of miniplates and miniscrews used for orthodontic anchorage: experience with 492 temporary anchorage devices.

    Science.gov (United States)

    Chen, Yi-Jane; Chang, Hao-Hueng; Lin, Hsing-Yi; Lai, Eddie Hsian-Hua; Hung, Hsin-Chia; Yao, Chung-Chen Jane

    2008-11-01

    The aim of this retrospective study was to evaluate systematically the potential factors that influence failure rates of temporary anchorage devices (TADs) used for orthodontic anchorage. Data on 492 TADs (miniplates, pre-drilling miniscrews, and self-drilling miniscrews) in 194 patients were collected. The factors related to TAD failure were evaluated using univariate analysis and multivariate forward stepwise logistic regression analysis. There were no significant differences in failure rates among the TADs for the following variables: gender, type of malocclusion, facial divergency, implantation site (buccal, lingual, or crestal/midpalatal), location (anterior or posterior), method of force application (power chain or Ni-Ti coil spring), arch (upper or lower), type of soft tissue (attached gingiva or removable mucosa), and most of the cephalometric measurements that reflect dento-cranio-facial characteristics. An increased failure rate was noted for the self-drilling miniscrew type of TAD, TADs used for tooth uprighting, those inserted on bone with lower density, those associated with local inflammation of the surrounding soft tissue, those loaded within 3 weeks after insertion, and those placed in patients with greater mandibular retrusion. Failure rates of the self-drilling miniscrews installed by an oral surgeon and by an orthodontist did not differ significantly. Inflammation of soft tissue surrounding a TAD and early loading within 3 weeks after insertion were the most significant factors predicting TAD failure. Both orthodontists and oral surgeons who install orthodontic TADs must undergo sufficient training to achieve clinical excellence.

  15. Numerical and Experimental Investigation on Root Anchorage

    Science.gov (United States)

    Ali, F.; Osman, N.; Hashim, R.; Khalilnejad, A.

    2012-04-01

    In more recent times, the roles played by vegetation in some specific geotechnical processes have been recognized. Vegetation may affect slope stability in many ways. The stability of slopes is governed by the load, which is the driving force that causes failure, and the resistance, which is the strength of the soil-root system. The weight of trees growing on a slope adds to the load but the roots of trees serve as a soil reinforcement and increase the resistance. In order to ensure that the weight of the trees on the slope help to enhance its stability it is required that they are planted down-slope of the neutral point. Maximum contribution is produced if the trees are located at the slope toe. Considering a typical slip circle, at this location the direction of shear force acting on the trees may be considered as close-to-vertical for the purpose of analysis. In this study, 3D numerical simulations of root anchorage have been performed to study the mechanism and the factors influencing the pull out capacity of tree roots. The investigation was performed using ABACUS finite element program. Field pull-out tests were also carried out on Melastoma malabathricum which been shown to be very suitable to be grown on slope, and the results are compared with numerical simulations. Parametric studies were also done to study the effects of factors such as root pattern, angle of inclination as well as soil properties. The results show that the 3D finite element analyses are able to approximately simulate the experimental tests. The results of the field tests, simulations and the parametric studies will be presented and discussed in more details in this paper.

  16. Effectiveness of 3 methods of anchorage reinforcement for maximum anchorage in adolescents: A 3-arm multicenter randomized clinical trial.

    Science.gov (United States)

    Sandler, Jonathan; Murray, Alison; Thiruvenkatachari, Badri; Gutierrez, Rodrigo; Speight, Paul; O'Brien, Kevin

    2014-07-01

    The objective of this 3-arm parallel randomized clinical trial was to compare the effectiveness of temporary anchorage devices (TADs), Nance button palatal arches, and headgear for anchorage supplementation in the treatment of patients with malocclusions that required maximum anchorage. This trial was conducted between August 2008 and February 2013 in 2 orthodontic departments in the United Kingdom. The study included 78 patients (ages, 12-18 years; mean age, 14.2 years) who needed maximum anchorage. Eligibility criteria included no active caries, exemplary oral hygiene, and maximum anchorage required. The primary outcome was mesial molar movement during the period in which anchorage supplementation was required. The secondary outcomes were duration of anchorage reinforcement, number of treatment visits, number of casual and failed appointments, total treatment time, dento-occlusal change, and patients' perceptions of the method of anchorage supplementation. Treatment allocation was implemented by contacting via the Internet the randomization center at the University of Nottingham, Clinical Trials Unit. The randomization was based on a computer-generated pseudo-random code with random permuted blocks of randomly varying size. A research assistant who was blinded to the group allocation recorded all data. The patients were randomly allocated to receive anchorage supplementation with TADs, a Nance button on a palatal arch, or headgear. They were all treated with maxillary and mandibular preadjusted edgewise fixed appliances with 0.022-in slot prescription brackets. They were followed until orthodontic treatment was complete. Seventy-eight patients were randomized in a 1:1:1 ratio among the 3 groups. The baseline characteristics were similar in the groups, and they were treated for an average of 27.4 months (SD, 7.1 months); 71 completed orthodontic treatment. The data were analyzed on a per-protocol basis and showed no differences in the effectiveness of anchorage

  17. FRP tendon anchorage in post-tensioned concrete structures

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Täljsten, Björn; Bennitz, Anders

    2008-01-01

    Strengthening of building structures by the use of various external post-tensioning steel tendon systems, is known to be a very efficient method. However, FRP as material in external post-tensioning projects has been investigated during the last decade. The advantages for this material are the high...... effective Young´s modulus and the high stress capacity in the linear elastic range of the material. The use of external tendons increases the requirements on the anchorage systems. This is in particular important when using un-bonded tendon systems, where the anchorage and deviators are the only force...... transfer points. The demand for high capacity anchorage tendons is fulfilled for steel tendons, but no competitive mechanical anchor has yet been developed for FRP tendon. A new small, reliable and more user friendly anchor has to be developed, before FRP tendons can be utilized with all of its capacity...

  18. Modification of evaluation response spectrum by ductility of equipment anchorage

    International Nuclear Information System (INIS)

    Choi, I. G.; Jun, Y. S.; Su, J. M.

    2003-01-01

    The failure mode of welded anchorage is assumed as brittle in the seismic capacity evaluation of nuclear power plant equipments. But the welded anchorage has some ductile capacity. This limited displacement capacity can cause the reduction of the effective frequency of high frequency equipments and the increase of the inelastic energy absorption capacity due to the nonlinear behavior. In this study, the uniform hazard spectrum for Korean nuclear power plant site was modified using the response spectrum reduction factor developed by EPRI. The spectral acceleration for various damping ratio was determined by the theoretical method based on the random vibration theory. In conclusion, the high frequency components of evaluation response spectra were greatly reduced due to the consideration of welded anchorage ductility. This reduced response spectra can be used for the development of in-structure response spectra used in the seismic capacity evaluation of high frequency equipments

  19. 77 FR 43514 - Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI

    Science.gov (United States)

    2012-07-25

    ...-AA01 Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI AGENCY: Coast Guard, DHS... Narragansett Bay, Rhode Island, and adding an offshore anchorage in Rhode Island Sound south of Brenton Point... rulemaking (NPRM) entitled ``Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI,'' in the...

  20. 77 FR 54493 - Special Anchorage Area; Stockton Springs, ME

    Science.gov (United States)

    2012-09-05

    ... 1625-AA01 Special Anchorage Area; Stockton Springs, ME AGENCY: Coast Guard, DHS. ACTION: Notice of... Springs, Maine. This proposed action is necessary to facilitate safe navigation in that area and provide... increase the safety of life and property in Stockton Springs, improve the safety of anchored vessels, and...

  1. Application and Curative Effect of Micro-implant Anchorage in ...

    African Journals Online (AJOL)

    Purpose: To explore and analyze the curative effects of micro - implant anchorages in orthodontics. Methods: A retrospective analysis of 65 patients undergoing orthodontic treatment in Department of Stomatology, Binzhou Medical University Hospital, Shandong, China was carried out. Thirty four cases in the treatment ...

  2. Shear and Anchorage Behaviour of Fire Exposed Hollow Core Slabs

    NARCIS (Netherlands)

    Fellinger, J.H.H.

    2004-01-01

    Hollow core (HC) slabs are made of precast concrete with pretensioned strands. These slabs are popular as floor structures in offices and housing. At ambient conditions, the load bearing capacity can be dominated by four different failure modes, i.e. flexure, anchorage, shear compression and shear

  3. Shear and anchorage behaviour of fire exposed hollow core slabs

    NARCIS (Netherlands)

    Fellinger, J.

    2005-01-01

    The fire resistance of hollow core slabs is currently assessed considering flexural failure only. However, fire tests show that shear or anchorage failure can also govern the load bearing behaviour. This paper is based on the dissertation by the author1 and discusses existing and new fire tests. It

  4. 75 FR 3641 - Television Broadcasting Services; Anchorage, AK

    Science.gov (United States)

    2010-01-22

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [DA 10-40; MB Docket No. 09-210; RM-11583] Television Broadcasting Services; Anchorage, AK AGENCY: Federal Communications Commission. ACTION: Final rule... review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television, Television...

  5. Finite element simulation and testing of ISW CFRP anchorage

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Goltermann, Per; Hertz, Kristian Dahl

    2013-01-01

    is modelled in the 3D finite Element program ABAQUS, just as digital image correlation (DIC) testing was performed to verify the finite element simulation. Also a new optimized design was produced to ensure that the finite element simulation and anchorage behaviour correlated well. It is seen...

  6. External post-tensioning of cfrp tendons using integrated sleeve-wedge anchorage

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Bennitz, Anders; Goltermann, Per

    2012-01-01

    Strengthening of structures using external post-tension CFRP systems have proven to be anefficient method as such system increases the structural capacity and reduces cracks and deflection. Sufficient anchorage is of significant importance since the anchorage provides the connection between...... anchorage was obtained using the novel anchorage and that its behaviour is stable and predicatble when short term static load is applied. Desired strengthening was also observed in external post-tensioning on reinforced concrete T-beams. The requirements and definitions on a stable anchorage of CFRP tendons...

  7. Research on the Bond Anchorage Properties of Alkali-Activated Slag Cementitious Material

    Science.gov (United States)

    Zhu, J.; Zheng, W. Z.; Leng, Y. F.; Qin, C. Z.; Xu, Z. Z.

    2017-12-01

    By bond-anchorage property tests at 20°C ∼500°C, the distribution of shear stress between carbon fiber sheets and concrete at all levels of loading and anchorage lengths were measured, which means the bond lengths during CFRP sheets are pulled off at the same time when the concrete is torn and stripped were gotten. The failure modes were obtained. In addition, the failure loads were measured, and the calculated formulas of anchorage lengths were identified by fitting at high temperature. It can be seen that the anchorage lengths of carbon fiber sheets increase with increasing temperature at 20°C ∼100°C, the anchorage lengths of carbon fiber sheets decrease with increasing temperature at 100°C ∼500°C. Tests prove that AASCM has favorable high-temperature resistant and bond anchorage properties.

  8. Research on Anchorage Performance of Grouting Anchor Connection of Precast Concrete Structure

    Science.gov (United States)

    Wang, Donghui; Liu, Xudong; Wang, Sheng; Cao, Xixi

    2018-03-01

    The bonding of grouted anchor bars is one of the vertical connection forms of steel bars in fabricated concrete structures. The performance of grouted connection is mainly affected by the anchorage length and lap length of steel bars. The mechanisms of bond and anchorage between steel bar and concrete are analyzed, and the factors that influence the anchorage performance of steel bar are systematically summarized. Results show that the bond and anchorage performance of steel and concrete have been studied widely, but there are still shortcomings, and the connection forms need to be further improved.

  9. Efficacy of the Nance appliance as an anchorage-reinforcement method.

    Science.gov (United States)

    Al-Awadhi, Ebrahim A; Garvey, Therese M; Alhag, Mohamed; Claffey, Noel M; O'Connell, Brian

    2015-03-01

    The Nance appliance is widely considered to be an efficient method of anchorage reinforcement; however, much of the perceived advantage is based on clinical judgment. The aim of this study was to assess the amounts of anchorage loss and desired tooth movement associated with the Nance appliance. The mandibular arches of 7 beagle dogs were used. The first and third premolars were extracted. Reference miniscrews were placed at the first premolar sites as stable references to measure the amounts of anchorage loss and desired tooth movement. Four beagles were fitted with custom-made Nance appliances on the fourth premolars and orthodontic bands on the second premolars (Nance group). Three beagles were fitted with orthodontic bands on the second and fourth premolars with no anchorage reinforcement (control group). The second premolars were retracted over 15 weeks in both groups. The amounts of second premolar movement (desired tooth movement) and fourth premolar movement (anchorage loss) were recorded at 5, 10, and 15 weeks. The percentages of desired tooth movement and anchorage loss to the total space closure were calculated. The mean desired tooth movement was significantly more in the Nance group than in the control group at 10 weeks (P appliance did not provide absolute anchorage, but there was significantly less anchorage loss with it than in the control group. The majority of anchorage loss occurred during the first 10 weeks in the Nance group. Copyright © 2015 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  10. Local application of zoledronate for maximum anchorage during space closure.

    Science.gov (United States)

    Ortega, Adam J A J; Campbell, Phillip M; Hinton, Robert; Naidu, Aparna; Buschang, Peter H

    2012-12-01

    Orthodontists have used various compliance-dependent physical means such as headgears and intraoral appliances to prevent anchorage loss. The aim of this study was to determine whether 1 local application of the bisphosphonate zoledronate could be used to prevent anchorage loss during extraction space closure in rats. Thirty rats had their maxillary left first molars extracted and their maxillary left second molars protracted into the extraction space with a 10-g nickel-titanium closing coil for 21 days. Fifteen control rats received a local injection of phosphate-buffered saline solution, and 15 experimental rats received 16 μg of the bisphosphonate zoledronate. Bisphosphonate was also delivered directly into the extraction site and left undisturbed for 5 minutes. Cephalograms and incremental thickness gauges were used to measure tooth movements. Tissues were analyzed by microcomputed tomography and histology. The control group demonstrated significant (P <0.05) tooth movements throughout the 21-day period. They showed significantly greater tooth movements than the experimental group beginning in the second week. The experimental group showed no significant tooth movement after the first week. The microcomputed tomography and histologic observations showed significant bone loss in the extraction sites and around the second molars of the controls. In contrast, the experimental group had bone preservation and bone fill. There was no evidence of bisphosphonate-associated osteonecrosis in any sample. A single small, locally applied dose of zoledronate provided maximum anchorage and prevented significant bone loss. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  11. Orthodontic space closure after first molar extraction without skeletal anchorage.

    Science.gov (United States)

    Jacobs, Collin; Jacobs-Müller, Claudia; Luley, Carolin; Erbe, Christina; Wehrbein, Heiner

    2011-03-01

    The aim of the study was an analysis of effects and side-effects during mesialization of second molars after extraction of the first permanent molars using the anterior dentition/premolars (PM) as an anchorage unit. A total of 35 patients were examined retrospectively who had undergone unilateral or bilateral first permanent molar extraction in the upper or lower arch due to carious lesions. Space closure was carried out in all cases through mesialization of the second molar using an elastic chain fixed to an edgewise stainless steel archwire and tying the anterior dentition/PM together with a continuous laceback ligature. Tooth movement was assessed from lateral cephalograms, orthopantomograms (OPGs) and images of the patient's study casts taken before and after the end of therapy. Space closure after first molar extractions by mesialization of the second molars without skeletal anchorage was largely achieved by bodily forward movement of the teeth, including a small tipping component or tooth-uprighting component when molars were already mesially inclined. Unilateral and bilateral mesialization of the second molars led to retrusion in the maxilla and mandible [(∆incl.=-3.6° (max., bil.), ∆incl.=-4.2° (mand., bil.)] and to translational retraction [(∆s=-2.3 mm (max., bil.), ∆s=-1.6 mm (mand., bil.)] of the incisors. Examination of the soft tissues revealed an increased posterior displacement of the upper and lower lips to the esthetic line [(∆s=-2.8 mm (max. bil.), ∆s=-2.2 mm (mand., bil.)]. In cases of unilateral mesialization less than 50% of the patients had a slight midline deviation in the mandible towards the extraction side. Side effects during mesialization of the second molars without skeletal anchorage in the anterior dentition/PM were observed primarily affecting the incisors integrated into the anterior anchorage unit. These side-effects resulted in posterior displacement of the soft tissues, including a change in profile. This must be

  12. Testing of large prestressing tendon end anchorage regions

    International Nuclear Information System (INIS)

    Johnson, T.E.

    1976-01-01

    Tests were performed on concrete end anchorage regions for prestressing tendons with ultimate strengths of approximately 8,900 kN. One test structure simulated a full scale concrete containment buttress and the other two test specimens were concrete blocks. The behavior of the test structure and specimens, when subjected to loading, was monitored by strain gages and dial gages. The testing illustrated that all of the amounts of reinforcing tested should be acceptable for the end anchor zones of large tendons presently used in prestressed concrete containment structures. (author)

  13. Comparative photoelastic study of dental and skeletal anchorages in the canine retraction

    Directory of Open Access Journals (Sweden)

    Cristiane Aparecida de Assis Claro

    2014-01-01

    Full Text Available OBJECTIVE: To compare dental and skeletal anchorages in mandibular canine retraction by means of a stress distribution analysis. METHODS: A photoelastic model was produced from second molar to canine, without the first premolar, and mandibular canine retraction was simulated by a rubber band tied to two types of anchorage: dental anchorage, in the first molar attached to adjacent teeth, and skeletal anchorage with a hook simulating the mini-implant. The forces were applied 10 times and observed in a circular polariscope. The stresses located in the mandibular canine were recorded in 7 regions. The Mann-Whitney test was employed to compare the stress in each region and between both anchorage systems. The stresses in the mandibular canine periradicular regions were compared by the Kruskal-Wallis test. RESULTS: Stresses were similar in the cervical region and the middle third. In the apical third, the stresses associated with skeletal anchorage were higher than the stresses associated with dental anchorage. The results of the Kruskal-Wallis test showed that the highest stresses were identified in the cervical-distal, apical-distal, and apex regions with the use of dental anchorage, and in the apical-distal, apical-mesial, cervical-distal, and apex regions with the use of skeletal anchorage. CONCLUSIONS: The use of skeletal anchorage in canine retraction caused greater stress in the apical third than the use of dental anchorage, which indicates an intrusive component resulting from the direction of the force due to the position of the mini-implant and the bracket hook of the canine.

  14. Comparative photoelastic study of dental and skeletal anchorages in the canine retraction

    Science.gov (United States)

    Claro, Cristiane Aparecida de Assis; Chagas, Rosana Villela; Neves, Ana Christina Elias Claro; da Silva-Concílio, Laís Regiane

    2014-01-01

    Objective To compare dental and skeletal anchorages in mandibular canine retraction by means of a stress distribution analysis. Methods A photoelastic model was produced from second molar to canine, without the first premolar, and mandibular canine retraction was simulated by a rubber band tied to two types of anchorage: dental anchorage, in the first molar attached to adjacent teeth, and skeletal anchorage with a hook simulating the mini-implant. The forces were applied 10 times and observed in a circular polariscope. The stresses located in the mandibular canine were recorded in 7 regions. The Mann-Whitney test was employed to compare the stress in each region and between both anchorage systems. The stresses in the mandibular canine periradicular regions were compared by the Kruskal-Wallis test. Results Stresses were similar in the cervical region and the middle third. In the apical third, the stresses associated with skeletal anchorage were higher than the stresses associated with dental anchorage. The results of the Kruskal-Wallis test showed that the highest stresses were identified in the cervical-distal, apical-distal, and apex regions with the use of dental anchorage, and in the apical-distal, apical-mesial, cervical-distal, and apex regions with the use of skeletal anchorage. Conclusions The use of skeletal anchorage in canine retraction caused greater stress in the apical third than the use of dental anchorage, which indicates an intrusive component resulting from the direction of the force due to the position of the mini-implant and the bracket hook of the canine. PMID:24713566

  15. The application of mini-implants for orthodontic anchorage.

    Science.gov (United States)

    Tseng, Y-C; Hsieh, C-H; Chen, C-H; Shen, Y-S; Huang, I-Y; Chen, C-M

    2006-08-01

    The aim of this study was to explore the use of mini-implants for skeletal anchorage, and to assess their stability and the causes of failure. Forty-five mini-implants were used in orthodontic treatment. The diameter of the implants was 2mm, and their lengths were 8, 10, 12 and 14mm. The drill procedure was directly through the cortical bone without any incision or flap operation. Two weeks later, a force of 100-200g was applied by an elastometric chain or NiTi coil spring. Risk factors for the failure of mini-implants were examined statistically using the Chi-square or Fisher exact test as applicable. The average placement time of a mini-implant was about 10-15min. Four mini-implants loosened after orthodontic force loading. The overall success rate was 91.1%. The location of the implant was the significant factor related to failure. In conclusion, the mini-implants are easy to insert for skeletal anchorage and could be successful in the control of tooth movement.

  16. 33 CFR 162.136 - Connecting waters from Lake Huron to Lake Erie; anchorage grounds.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Connecting waters from Lake Huron to Lake Erie; anchorage grounds. 162.136 Section 162.136 Navigation and Navigable Waters COAST GUARD... REGULATIONS § 162.136 Connecting waters from Lake Huron to Lake Erie; anchorage grounds. (a) In the Detroit...

  17. 76 FR 15246 - Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI

    Science.gov (United States)

    2011-03-21

    ...-AA01 Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI AGENCY: Coast Guard, DHS... Rhode Island Sound south of Brenton Point, Rhode Island, for use by vessels waiting to enter... Sound that under current informal practice is routinely used by mariners as an anchorage while waiting...

  18. Flexural Strengthening of RC Slabs with Prestressed CFRP Strips Using Different Anchorage Systems

    Directory of Open Access Journals (Sweden)

    José Sena-Cruz

    2015-10-01

    Full Text Available Externally Bonded Reinforcement (EBR technique has been widely used for flexural strengthening of concrete structures by using carbon fiber-reinforced polymers (CFRP. EBR technique offers several structural advantages when the CFRP material is prestressed. This paper presents an experimental and numerical study on reinforced (RC slabs strengthened in flexure with prestressed CFRP strips as a structural strengthening system. The strips are applied as an externally bonded reinforcement (EBR and anchored with either a mechanical or a gradient anchorage. The former foresees metallic anchorage plates fixed to the concrete substrate, while the latter is based on an accelerated epoxy resin curing followed by a segment-wise prestress force decrease at the strip ends. Both anchorage systems, in combination with different CFRP strip geometries, were subjected to static loading tests. It could be demonstrated that the composite strip’s performance is better exploited when prestressing is used, with slightly higher overall load carrying capacities for mechanical anchorages than for the gradient anchorage. The performed investigations by means of a cross-section analysis supported the experimental observation that in case a mechanical anchorage is used, progressive strip debonding changes the fully bonded configuration to an unbonded end-anchored system. The inclusion of defined debonding criteria for both the anchorage zones and free length between the anchorage regions allowed to precisely capture the ultimate loading forces.

  19. 33 CFR 166.200 - Shipping safety fairways and anchorage areas, Gulf of Mexico.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Shipping safety fairways and anchorage areas, Gulf of Mexico. 166.200 Section 166.200 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY SHIPPING SAFETY FAIRWAYS Designations of Fairways and Fairway Anchorages §...

  20. Mini-Implants in the Anchorage Armamentarium: New Paradigms in the Orthodontics

    Directory of Open Access Journals (Sweden)

    Masaru Yamaguchi

    2012-01-01

    Full Text Available Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD. These devices are small, are implanted with a relatively simple surgical procedure, and increase the potential for better orthodontic results. Therefore, miniscrews not only free orthodontists from anchorage-demanding cases, but they also enable clinicians to have good control over tooth movement in 3 dimensions. The miniplate type also produces significant improvements in treatment outcomes and has widened the spectrum of orthodontics. The purpose of this paper is to update clinicians on the current concepts and versatile uses and clinical applications of skeletal anchorage in orthodontics.

  1. Anchorage Failure of RC beams strengthened with FRP at the bottom face

    DEFF Research Database (Denmark)

    Täljsten, Björn; Arifovic, Fedja

    2009-01-01

    When RC beams are strengthened by FRP plates bonded to the bottom face of the beam they fail due to the lack of the mechanical anchorage of the plate. This paper shows that it is possible to relate the anchorage failure of tension face FRP-plated beams to the crack sliding capacity of the beams...... of tension face plated beams. The assumption is that the FRP-plate must be extended at least one critical anchorage length beyond the theoretical occurrence of the critical diagonal crack........ The method suggested gives the highly desirable occurrence of the critical diagonal shear crack. The occurrence of this crack is suggested as the anchorage failure mechanism of the plate. The failure load that produces the sliding in such crack is shown to be a lower bound to the anchorage failure load...

  2. 33 CFR 165.556 - Regulated Navigation Area; Chesapeake and Delaware Canal, Chesapeake City Anchorage Basin, MD.

    Science.gov (United States)

    2010-07-01

    ...; Chesapeake and Delaware Canal, Chesapeake City Anchorage Basin, MD. 165.556 Section 165.556 Navigation and..., Chesapeake City Anchorage Basin, MD. (a) Location. The following area is a regulated navigation area: All waters of the Chesapeake and Delaware (C & D) Canal within the anchorage basin at Chesapeake City...

  3. 1964 Great Alaska Earthquake: a photographic tour of Anchorage, Alaska

    Science.gov (United States)

    Thoms, Evan E.; Haeussler, Peter J.; Anderson, Rebecca D.; McGimsey, Robert G.

    2014-01-01

    On March 27, 1964, at 5:36 p.m., a magnitude 9.2 earthquake, the largest recorded earthquake in U.S. history, struck southcentral Alaska (fig. 1). The Great Alaska Earthquake (also known as the Good Friday Earthquake) occurred at a pivotal time in the history of earth science, and helped lead to the acceptance of plate tectonic theory (Cox, 1973; Brocher and others, 2014). All large subduction zone earthquakes are understood through insights learned from the 1964 event, and observations and interpretations of the earthquake have influenced the design of infrastructure and seismic monitoring systems now in place. The earthquake caused extensive damage across the State, and triggered local tsunamis that devastated the Alaskan towns of Whittier, Valdez, and Seward. In Anchorage, the main cause of damage was ground shaking, which lasted approximately 4.5 minutes. Many buildings could not withstand this motion and were damaged or collapsed even though their foundations remained intact. More significantly, ground shaking triggered a number of landslides along coastal and drainage valley bluffs underlain by the Bootlegger Cove Formation, a composite of facies containing variably mixed gravel, sand, silt, and clay which were deposited over much of upper Cook Inlet during the Late Pleistocene (Ulery and others, 1983). Cyclic (or strain) softening of the more sensitive clay facies caused overlying blocks of soil to slide sideways along surfaces dipping by only a few degrees. This guide is the document version of an interactive web map that was created as part of the commemoration events for the 50th anniversary of the 1964 Great Alaska Earthquake. It is accessible at the U.S. Geological Survey (USGS) Alaska Science Center website: http://alaska.usgs.gov/announcements/news/1964Earthquake/. The website features a map display with suggested tour stops in Anchorage, historical photographs taken shortly after the earthquake, repeat photography of selected sites, scanned documents

  4. Gummy smile and facial profile correction using miniscrew anchorage.

    Science.gov (United States)

    Kaku, Masato; Kojima, Shunichi; Sumi, Hiromi; Koseki, Hiroyuki; Abedini, Sara; Motokawa, Masahide; Fujita, Tadashi; Ohtani, Junji; Kawata, Toshitsugu; Tanne, Kazuo

    2012-01-01

    This case report describes the treatment of a case involving a skeletal Class II facial profile with a gummy smile. While treating a facial profile and a gummy smile, the outcome may not always be successful with orthodontic therapy alone. For this reason, surgical therapy is often chosen to gain an esthetic facial profile and a good smile. However, sometimes the patients reject surgical treatment and an alternative method must be considered. Skeletal anchorage systems such as miniscrews are now frequently used for correcting severe malocclusion that should be treated by surgical therapy. In this case report, we treated a skeletal Class II malocclusion with a convex profile and a gummy smile using miniscrews, which were placed in the upper posterior and anterior areas. The active treatment period was 3.5 years, and the patient's teeth continued to be stable after a retention period of 36 months.

  5. Inspection Mechanism and Experimental Study of Prestressed Reverse Tension Method under PC Beam Bridge Anchorage

    Science.gov (United States)

    Peng, Zhang

    2018-03-01

    the prestress under anchorage is directly related to the structural security and performance of PC beam bridge. The reverse tension method is a kind of inspection which confirms the prestress by exerting reversed tension load on the exposed prestressing tendon of beam bridge anchoring system. The thesis elaborately expounds the inspection mechanism and mechanical effect of reverse tension method, theoretically analyzes the influential elements of inspection like tool anchorage deformation, compression of conjuncture, device glide, friction of anchorage loop mouth and elastic compression of concrete, and then presents the following formula to calculate prestress under anchorage. On the basis of model experiment, the thesis systematically studies some key issues during the reverse tension process of PC beam bridge anchorage system like the formation of stress-elongation curve, influential factors, judgment method of prestress under anchorage, variation trend and compensation scale, verifies the accuracy of mechanism analysis and demonstrates: the prestress under anchorage is less than or equal to 75% of the ultimate strength of prestressing tendon, the error of inspect result is less than 1%, which can meet with the demands of construction. The research result has provided theoretical basis and technical foundation for the promotion and application of reverse tension in bridge construction.

  6. Comparison of anchorage reinforcement with temporary anchorage devices or a Herbst appliance during lingual orthodontic protraction of mandibular molars without maxillary counterbalance extraction.

    Science.gov (United States)

    Metzner, Rebecca; Schwestka-Polly, Rainer; Helms, Hans-Joachim; Wiechmann, Dirk

    2015-06-20

    Orthodontic protraction of mandibular molars without maxillary counterbalance extraction in cases of aplasia or extraction requires stable anchorage. Reinforcement may be achieved by using either temporary anchorage devices (TAD) or a fixed, functional appliance. The objective was to compare the clinical effectiveness of both methods by testing the null-hypothesis of no significant difference in velocity of space closure (in mm/month) between them. In addition, we set out to describe the quality of posterior space management and treatment-related factors, such as loss of anchorage (assessed in terms of proportions of gap closure by posterior protraction or anterior retraction), frequencies of incomplete space closure, and potential improvement in the sagittal canine relationship. Twenty-seven subjects (15 male/12 female) with a total of 36 sites treated with a lingual multi-bracket appliance were available for retrospective evaluation of the effects of anchorage reinforcement achieved with either a Herbst appliance (n(subjects) = 15; 7 both-sided/8 single-sided Herbst appliances; n(sites) = 22) or TADs (n(subjects )= 12; 2 both-sided; 10 single-sided; n(sites) = 14). Descriptive analysis was based on measurements using intra-oral photographs which were individually scaled to corresponding plaster casts and taken on insertion of anchorage mechanics (T1), following removal of anchorage mechanics (T2), and at the end of multi-bracket treatment (T3). The null-hypothesis was rejected: The rate of mean molar protraction was significantly faster in the Herbst-reinforced group (0.51 mm/month) than in the TAD group (0.35). While complete space closure by sheer protraction of posterior teeth was achieved in all Herbst-treated cases, space closure in the TAD group was achieved in 76.9% of subjects by sheer protraction of molars, and it was incomplete in 50% of cases (mean gap residues: 1 mm). Whilst there was a deterioration in the canine relationship towards

  7. 77 FR 5743 - Special Anchorage Areas; Port of New York, NY

    Science.gov (United States)

    2012-02-06

    ... along the shoreline they fall within the jurisdiction of the States of New Jersey and New York. Both New... special anchorage areas in Sheepshead Bay, NY. We expect minimal additional cost impacts on the tug and...

  8. Calculation of absorbed dose of anchorage-dependent cells from internal beta-rays irradiation

    International Nuclear Information System (INIS)

    Chen Jianwei; Huang Gang; Li Shijun

    2001-01-01

    Objective: To elicit the formula of internal dosimetry in anchorage-dependent cells by beta-emitting radionuclides from uniformly distributed volume sources. Methods: By means of the definition of absorbed dose and the MIRD (Medical International Radiation Dose) scheme the formula of internal dosimetry was reasonably deduced. Firstly, studying the systems of suspension culture cells. Then, taking account of the speciality of the systems of the anchorage-dependent cells and the directions of irradiation, the absorbed dose of anchorage -dependent cells was calculated by the accumulated radioactivity, beta-ray energy, and the volume of the cultured systems. Results: The formula of internal dosimetry of suspension culture cells and anchorage-dependent cells were achieved. At the same time, the formula of internal dosimetry of suspension culture cells was compared with that of MIRD and was confirmed accurate. Conclusion: The formula of internal dosimetry is concise, reliable and accurate

  9. Transfer and anchorage bond behaviour in self-compacting concrete

    Directory of Open Access Journals (Sweden)

    Rigueira-Víctor, J. W.

    2006-12-01

    Full Text Available Self-compacting concretes (SCC provide solutions to the problems facing precast concrete construction, enhancing competitiveness, reducing turnaround times and improving final product quality. SCC is fast becoming a key product for the future development of the precast pre-stressed concrete industry.The present paper compares the bond performance of SCC and traditional concrete (TC. The bond performance results confirm the viability of SCC in precast pre-stressed concrete manufacture, despite a slightly higher loss of pre-stressing force and slightly greater anchorage lengths in SCC with a low water/cement ratio. No differences in transfer or anchorage length were detected,however, when high strength TC and SCC were compared. The ECADA test method proved to be well suited to detecting the differences between the concretes analyzed.El desarrollo de los hormigones autocompactantes (SCCofrece muchas posibilidades a las construcciones con hormigón prefabricado, aumentando su competitividad, reduciéndolos plazos de fabricación y ofreciendo mejoras en la calidad del producto final. El SCC se está convirtiendo en un producto clave para el futuro desarrollo de la industria de prefabricados de hormigón pretensado.En este estudio se compara el comportamiento adherente de los SCC con el de los hormigones tradicionales (TC actuales. Los resultados obtenidos confirman la viabilidad del uso de los SCC para la fabricación de elementos prefabricados con hormigón pretensado, en lo relativo a su comportamiento adherente, aunque con la necesidad de considerar unas pérdidas de pretensado ligeramente mayores. Asimismo,debe esperarse un ligero aumento de las longitudes de anclaje cuando se trabaje con SCC de baja relación agua/cemento. Sin embargo, no se han detectado diferencias de comportamiento entre ambos tipos de hormigón cuando la resistencia a compresión es alta en lo relativo a las longitudes de transmisión y anclaje. El método de ensayo ECADA

  10. Lingual orthodontic treatment and absolute anchorage to correct an impacted maxillary canine in an adult.

    Science.gov (United States)

    Chaushu, Stella; Becker, Adrian; Chaushu, Gavriel

    2008-12-01

    There are 2 major drawbacks to the classic orthodontic-surgical approach for resolution of impacted teeth in adults: appearance and duration of treatment. This case report illustrates the lingual orthodontic treatment of an adult with an impacted maxillary canine; absolute anchorage was achieved with a miniscrew placed in the palate. The combination of invisible appliances and a nondental anchorage system is particularly useful in adults and should make treatment available to more patients.

  11. Concrete Growth and Fatigue Analysis of Chickamauga Lock Miter Gate Anchorages

    Science.gov (United States)

    2017-09-19

    ER D C TR -1 7- 10 Concrete Growth and Fatigue Analysis of Chickamauga Lock Miter Gate Anchorages En gi ne er R es ea rc h an d D...default. ERDC TR-17-10 September 2017 Concrete Growth and Fatigue Analysis of Chickamauga Lock Miter Gate Anchorages Matthew D. Smith, Allen...failure is expected. This analysis included a review of existing structural analysis reports, estimates and prediction of observed concrete growth in

  12. 78 FR 9811 - Anchorages; Captain of the Port Puget Sound Zone, WA

    Science.gov (United States)

    2013-02-12

    ... area with a radius of 600 yards, having its center at 48 31'09'' N, 122 34'55'' W. (11) Cap Sante Tug and Barge General Anchorage. The Cap Sante Tug and Barge General Anchorage includes all waters... northeast tip of Cap Sante; then southeast to 48 30'53'' N, 122 35'28'' W; then west southwest to 48 30'45...

  13. Maxillary protraction at early ages. The revolution of new bone anchorage appliances.

    Science.gov (United States)

    Solano-Mendoza, B; Iglesias-Linares, A; Yañez-Vico, R M; Mendoza-Mendoza, A; Alió-Sanz, J J; Solano-Reina, E

    2012-01-01

    An update is provided on the different types of early treatment for class III malocclusions of maxillary origin. There is an increasing tendency to prescribe maxillary orthopedic treatment with skeletal anchorage, with the purpose of enhancing the skeletal and reducing the dentoalveolar effects--offering a management option for children with important deformations that otherwise would have to wait until adult age to receive surgical treatment. A literature review has been made of maxillary bone orthopedic traction appliances in growing children with class III malocclusions. A Medline (PubMed) search was made using the following MeSH terms: Cephalometric, Child, Malocclusion class III/therapy, Extraoral traction appliances, Palatal expansion, Bone plates, Skeletal anchorage, Orthodontic anchorage. Many articles show that the greatest maxillary advances are obtained at very early ages, though with a greater tendency towards relapse. However skeletal anchorage has been seen to afford a lesser relapse rate and greater dentofacial orthopedic efficiency due to its low dentoalveolar impact. In any case, further randomized clinical studies are needed to firmly establish the quantifiable differences in terms of maxillary advance, optimum traction age, optimum traction appliance and potential side effects. At present, the incorporation of surgically inserted bone anchorage appliances (miniplates and miniscrews) offers a purely orthopedic approach to treatment, with minimization of the undesirable side effects of traditional dentofacial orthopedic compensation based on dentoalveolar anchorage. Nevertheless, further studies are needed to consolidate the supporting scientific evidence in this field.

  14. Virtual planning for vertical control using temporary anchorage devices

    Directory of Open Access Journals (Sweden)

    Mauricio Accorsi

    2015-01-01

    Full Text Available The new and innovative technologies are unprecedentedly improving the level of proficiency in orthodontics in the recent history of this area of expertise. The proliferation of advances, such as self-ligating systems, temporary anchorage devices, shape-memory wires, robotically wire bending, intraoral scanners, cone-beam computed tomography, bring the virtual planning, and confection of dental devices through CAD/CAM systems to the real world. In order to get efficiency and efficacy in orthodontics with these new technologies, we must understand the importance of systemically managed clinical information, medical, and dentistry history of the patients, including the images resources, which ensures the use of a communication that is assisted by the technology, with an interdisciplinary team so that the database is able to help and support the process of therapeutic decision-making. This paper presents the clinical case of a borderline patient for orthognathic surgery who had his final treatment planning supported by these new tools for three-dimensional diagnosis and virtual planning.

  15. Isolated scaphotrapeziotrapezoid osteoarthritis treatment using resurfacing arthroplasty with scaphoid anchorage.

    Science.gov (United States)

    Humada Álvarez, G; Simón Pérez, C; García Medrano, B; Faour Martín, O; Marcos Rodríguez, J J; Vega Castrillo, A; Martín Ferrero, M A

    The aim of this study is to show the results of scaphotrapeziotrapezoid (STT) joint osteoarthritis treatment performing resurfacing arthroplasty with scaphoid anchorage. An observational, descriptive and retrospective study was performed. Ten patients with isolated STT joint osteoarthritis were studied between 2013 and 2015. The mean follow-up time was 26months. Clinical results, functional and subjective scores were reviewed. The patients were satisfied, achieving an average of 2.1 (0-3) on the VAS score and 16 (2 to 28) in the DASH questionnaire, and returning to work in the first three months post-surgery. Recovery of range of motion compared to the contralateral wrist was 96% in extension, 95% in flexion, 87% in ulnar deviation and 91% in radial deviation. The average handgrip strength of the wrist was 95% and pinch strength was 95% compared to the contralateral side. There were no intraoperative complications or alterations in postoperative carpal alignment. Resurfacing arthroplasty is proposed as a good and novel alternative in treating isolated SST joint arthritis. Achieving the correct balance between the strength and mobility of the wrist, without causing carpal destabilisation, is important to obtain satisfactory clinical and functional results. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  16. Experimental study and stress analysis of rock bolt anchorage performance

    Directory of Open Access Journals (Sweden)

    Yu Chen

    2014-10-01

    Full Text Available A new method was developed to apply pull-and-shear loads to the bolt specimen in order to evaluate the anchorage performance of the rebar bolt and the D-Bolt. In the tests, five displacing angles (0°, 20°, 40°, 60°, and 90°, two joint gaps (0 mm and 30 mm, and three kinds of host rock materials (weak concrete, strong concrete, and concrete-granite were considered, and stress–strain measurements were conducted. Results show that the ultimate loads of both the D-Bolt and the rebar bolt remained constant with any displacing angles. The ultimate displacement of the D-Bolt changed from 140 mm at the 0° displacing angle (pure pull to approximately 70 mm at a displacing angle greater than 40°. The displacement capacity of the D-Bolt is approximately 3.5 times that of the rebar bolt under pure pull and 50% higher than that of the rebar bolt under pure shear. The compressive stress exists at 50 mm from the bolt head, and the maximum bending moment value rises with the increasing displacing angle. The rebar bolt mobilises greater applied load than the D-Bolt when subjected to the maximum bending. The yielding length (at 0° of the D-Bolt is longer than that of the rebar bolt. The displacement capacity of the bolts increased with the joint gap. The bolt subjected to joint gap effect yields more quickly with greater bending moment and smaller applied load. The displacement capacities of the D-Bolt and the rebar bolt are greater in the weak host rock than that in the hard host rock. In pure shear condition, the ultimate load of the bolts slightly decreases in the hard rock. The yielding speed in the hard rock is higher than that in the weak rock.

  17. Maxillary incisors changes during space closure with conventional and skeletal anchorage methods: a systematic review.

    Science.gov (United States)

    Jayaratne, Yasas Shri Nalaka; Uribe, Flavio; Janakiraman, Nandakumar

    2017-01-01

    The objective of this systematic review was to compare the antero-posterior, vertical and angular changes of maxillary incisors with conventional anchorage control techniques and mini-implant based space closure methods. The electronic databases Pubmed, Scopus, ISI Web of knowledge, Cochrane Library and Open Grey were searched for potentially eligible studies using a set of predetermined keywords. Full texts meeting the inclusion criteria as well as their references were manually searched. The primary outcome data (linear, angular, and vertical maxillary incisor changes) and secondary outcome data (overbite changes, soft tissue changes, biomechanical factors, root resorption and treatment duration) were extracted from the selected articles and entered into spreadsheets based on the type of anchorage used. The methodological quality of each study was assessed. Six studies met the inclusion criteria. The amount of incisor retraction was greater with buccally placed mini-implants than conventional anchorage techniques. The incisor retraction with indirect anchorage from palatal mini-implants was less when compared with buccally placed mini-implants. Incisor intrusion occurred with buccal mini-implants, whereas extrusion was seen with conventional anchorage. Limited data on the biomechanical variables or adverse effects such as root resorption were reported in these studies. More RCT's that take in to account relevant biomechanical variables and employ three-dimensional quantification of tooth movements are required to provide information on incisor changes during space closure.

  18. Quantification of temperature effect on impedance monitoring via PZT interface for prestressed tendon anchorage

    Science.gov (United States)

    Huynh, Thanh-Canh; Kim, Jeong-Tae

    2017-12-01

    In this study, the quantification of temperature effect on impedance monitoring via a PZT interface for prestressed tendon-anchorage is presented. Firstly, a PZT interface-based impedance monitoring technique is selected to monitor impedance signatures by predetermining sensitive frequency bands. An analytical model is designed to represent coupled dynamic responses of the PZT interface-tendon anchorage system. Secondly, experiments on a lab-scaled tendon anchorage are described. Impedance signatures are measured via the PZT interface for a series of temperature and prestress-force changes. Thirdly, temperature effects on measured impedance responses of the tendon anchorage are estimated by quantifying relative changes in impedance features (such as RMSD and CCD indices) induced by temperature variation and prestress-force change. Finally, finite element analyses are conducted to investigate the mechanism of temperature variation and prestress-loss effects on the impedance responses of prestressed tendon anchorage. Temperature effects on impedance monitoring are filtered by effective frequency shift-based algorithm for distinguishing prestress-loss effects on impedance signatures.

  19. MAXILLARY INCISORS CHANGES DURING SPACE CLOSURE WITH CONVENTIONAL AND SKELETAL ANCHORAGE METHODS: A SYSTEMATIC REVIEW

    Directory of Open Access Journals (Sweden)

    Yasas Shri Nalaka JAYARATNE

    2017-12-01

    Full Text Available Purpose: The objective of this systematic review was to compare the antero-posterior, vertical and angular changes of maxillary incisors with conventional anchorage control techniques and mini-implant based space closure methods. Materials and Methods: The electronic databases Pubmed, Scopus, ISI Web of knowledge, Cochrane Library and Open Grey were searched for potentially eligible studies using a set of predetermined keywords. Full texts meeting the inclusion criteria as well as their references were manually searched. The primary outcome data (linear, angular, and vertical maxillary incisor changes and secondary outcome data (overbite changes, soft tissue changes, biomechanical factors, root resorption and treatment duration were extracted from the selected articles and entered into spreadsheets based on the type of anchorage used. The methodological quality of each study was assessed. Results: Six studies met the inclusion criteria. The amount of incisor retraction was greater with buccally placed mini-implants than conventional anchorage techniques. The incisor retraction with indirect anchorage from palatal mini-implants was less when compared with buccally placed mini-implants. Incisor intrusion occurred with buccal mini-implants, whereas extrusion was seen with conventional anchorage. Limited data on the biomechanical variables or adverse effects such as root resorption were reported in these studies. Conclusion: More RCT’s that take in to account relevant biomechanical variables and employ three-dimensional quantification of tooth movements are required to provide information on incisor changes during space closure.

  20. Adult Class II Division 1 patient with severe gummy smile treated with temporary anchorage devices.

    Science.gov (United States)

    Shu, Rui; Huang, Lan; Bai, Ding

    2011-07-01

    A 23-year-old Mongolian woman came for a consultation with chief complaints of protrusive lips and a gummy smile. The clinical examination showed a convex profile, a protrusive maxilla, excessively proclined and extruded maxillary incisors, and a Class II Division 1 malocclusion. Temporary anchorage devices (TADs) in the posterior dental region were used as anchorage for the retraction and intrusion of her maxillary anterior teeth. Those appliances, combined with a compensatory curved maxillary archwire, eliminated the severe gummy smile and the protrusive profile, and corrected the molar relationship from Class II to Class I. With no extra temporary anchorage devices in the anterior region for intrusion, the treatment was workable and simple. The patient received a satisfactory occlusion and an attractive smile. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  1. Mini-implants and miniplates generate sub-absolute and absolute anchorage.

    Science.gov (United States)

    Consolaro, Alberto

    2014-01-01

    The functional demand imposed on bone promotes changes in the spatial properties of osteocytes as well as in their extensions uniformly distributed throughout the mineralized surface. Once spatial deformation is established, osteocytes create the need for structural adaptations that result in bone formation and resorption that happen to meet the functional demands. The endosteum and the periosteum are the effectors responsible for stimulating adaptive osteocytes in the inner and outer surfaces. Changes in shape, volume and position of the jaws as a result of skeletal correction of the maxilla and mandible require anchorage to allow bone remodeling to redefine morphology, esthetics and function as a result of spatial deformation conducted by orthodontic appliances. Examining the degree of changes in shape, volume and structural relationship of areas where mini-implants and miniplates are placed allows us to classify mini-implants as devices of subabsolute anchorage and miniplates as devices of absolute anchorage.

  2. Mini-implants and miniplates generate sub-absolute and absolute anchorage

    Directory of Open Access Journals (Sweden)

    Alberto Consolaro

    2014-06-01

    Full Text Available The functional demand imposed on bone promotes changes in the spatial properties of osteocytes as well as in their extensions uniformly distributed throughout the mineralized surface. Once spatial deformation is established, osteocytes create the need for structural adaptations that result in bone formation and resorption that happen to meet the functional demands. The endosteum and the periosteum are the effectors responsible for stimulating adaptive osteocytes in the inner and outer surfaces.Changes in shape, volume and position of the jaws as a result of skeletal correction of the maxilla and mandible require anchorage to allow bone remodeling to redefine morphology, esthetics and function as a result of spatial deformation conducted by orthodontic appliances. Examining the degree of changes in shape, volume and structural relationship of areas where mini-implants and miniplates are placed allows us to classify mini-implants as devices of subabsolute anchorage and miniplates as devices of absolute anchorage.

  3. Anchorage of titanium implants with different surface characteristics: an experimental study in rabbits

    DEFF Research Database (Denmark)

    Gotfredsen, K; Berglundh, T; Lindhe, J

    2000-01-01

    was performed after 1 and 3 weeks. Removal torque (RMT) tests of the implants were performed 4 weeks after the second surgery in group A and 9 weeks after the second surgery in group B. Thus, in group A, two healing groups were created, representing 4 and 6 weeks, respectively. The corresponding healing groups......: The present study demonstrated that a clear relation exists between surface roughness, described in Sa values, and implant anchorage assessed by RMT measurements. The anchorage appeared to increase with the maturation of bone tissue during healing....

  4. A Manual for the Anchorage School District Bilingual Education Program Revised Scope and Sequence, K-3.

    Science.gov (United States)

    Heinrich, Maria Nieves Bumanlag Lilagan

    The manual offers a systematic set of procedures and relevant information to facilitate effective use of the Anchorage school district (ASD) bilingual education program (BEP). The historical background of the program's development is presented, available manuals for teaching English to limited English proficiency (LEP) students and related…

  5. 77 FR 35104 - Notice of Request To Release Airport Property at Merrill Field Airport, Anchorage, AK

    Science.gov (United States)

    2012-06-12

    ... delivered to: Michelle Colby, Real Estate Services Manager, DOWL HKM, 4041 B Street, Anchorage, AK 99503...- 271-3665, email [email protected] or Michelle Colby, Real Estate Services Manager, DOWL HKM, 4041... Section 6.13 of the State of Alaska Right of Way Manual. This purchase offer was predicated on DOT&PF's...

  6. Thick-Walled Cylinder Theory Applied on a Conical Wedge Anchorage

    DEFF Research Database (Denmark)

    Bennitz, Anders; Grip, Niklas; Schmidt, Jacob Wittrup

    2011-01-01

    Conical wedge anchorages are frequently used to anchor steel tendons in prestressing applications within the construction industry. To replace the steel tendons with non-corrosive and low weight FRPs (Fiber Reinforced Polymers), the different mechanical interactions between the steel and FRPs call...

  7. Biofilm formation on surface characterized micro-implants for skeletal anchorage in orthodontics

    NARCIS (Netherlands)

    Chin, Yeen; Sandham, John; de Vries, Jacob; van der Mei, Henderina; Busscher, Hendrik

    Micro-implants are increasingly popular in clinical orthodontics to effect skeletal anchorage. However, biofilm formation on their surfaces and subsequent infection of peri-implant tissues can result in either exfoliation or surgical removal of these devices. The present study aimed to assess

  8. Revisiting the stability of mini-implants used for orthodontic anchorage

    Directory of Open Access Journals (Sweden)

    Chung-Chen Jane Yao

    2015-11-01

    Conclusion: This study revealed that once the dental surgeon becomes familiar with the procedure, the stability of orthodontic mini-implants depends on the type of mini-implant, age of the patient, implantation site, and the healing time of the mini-implant. Miniplates are a more feasible anchorage system when miniscrews fail repeatedly.

  9. Evaluating School Wellness Policy in Curbing Childhood Obesity in Anchorage, Alaska

    Science.gov (United States)

    Parsons, Wendy G.; Garcia, Gabriel M.; Hoffman, Pamela K.

    2014-01-01

    In 2006, the Anchorage School District implemented a school wellness policy to address the problem of obesity among its elementary-aged students. We assessed whether the addition of this policy is effective in protecting or preventing students from becoming overweight/obese over time. The methods involved following two cohorts of students for 5…

  10. SATB2 expression increased anchorage-independent growth and cell migration in human bronchial epithelial cells

    International Nuclear Information System (INIS)

    Wu, Feng; Jordan, Ashley; Kluz, Thomas; Shen, Steven; Sun, Hong; Cartularo, Laura A.; Costa, Max

    2016-01-01

    The special AT-rich sequence-binding protein 2 (SATB2) is a protein that binds to the nuclear matrix attachment region of the cell and regulates gene expression by altering chromatin structure. In our previous study, we reported that SATB2 gene expression was induced in human bronchial epithelial BEAS-2B cells transformed by arsenic, chromium, nickel and vanadium. In this study, we show that ectopic expression of SATB2 in the normal human bronchial epithelial cell-line BEAS-2B increased anchorage-independent growth and cell migration, meanwhile, shRNA-mediated knockdown of SATB2 significantly decreased anchorage-independent growth in Ni transformed BEAS-2B cells. RNA sequencing analyses of SATB2 regulated genes revealed the enrichment of those involved in cytoskeleton, cell adhesion and cell-movement pathways. Our evidence supports the hypothesis that SATB2 plays an important role in BEAS-2B cell transformation. - Highlights: • We performed SATB2 overexpression in the BEAS-2B cell line. • We performed SATB2 knockdown in a Ni transformed BEAS-2B cell line. • SATB2 induced anchorage-independent growth and increased cell migration. • SATB2 knockdown significantly decreased anchorage-independent growth. • We identified alterations in gene involved in cytoskeleton, cell adhesion.

  11. A study of the mechanical strength of miniscrews and miniplates for skeletal anchorage

    Directory of Open Access Journals (Sweden)

    Pei-Chen Lu

    2011-09-01

    Conclusions: Successful outcomes were confirmed for the skeletal anchorage concept for orthodontic treatment using miniscrews and miniplates. The mechanical strength of the miniscrews and miniplates was studied to prove the stability of fixation to resist orthodontic forces in the vertical and horizontal directions.

  12. 77 FR 19155 - Federal Motor Vehicle Safety Standards; Seat Belt Assembly Anchorages; Incorporation by Reference

    Science.gov (United States)

    2012-03-30

    ... Participation I. FMVSS No. 210 FMVSS No. 210, ``Seat belt assembly anchorages,'' applies to passenger cars, multipurpose passenger vehicles (MPVs), trucks, and buses. The standard establishes requirements for seat belt.... 210 and Figure 2 in FMVSS No. 222, ``School bus passenger seating and crash protection''). \\1\\ For lap...

  13. 75 FR 66686 - Federal Motor Vehicle Safety Standards; Seat Belt Assembly Anchorages, School Bus Passenger...

    Science.gov (United States)

    2010-10-29

    ... Anchorages, School Bus Passenger Seating and Crash Protection AGENCY: National Highway Traffic Safety... published on October 21, 2008, which upgraded NHTSA's school bus passenger crash protection requirements.... We make clearer the procedure specifying how we will measure the height of school bus passenger torso...

  14. 76 FR 80394 - Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK

    Science.gov (United States)

    2011-12-23

    ... DEPARTMENT OF THE INTERIOR National Park Service [2253-665] Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Alaska State Office, Bureau of Land Management has completed an inventory of human...

  15. 75 FR 23804 - Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK...

    Science.gov (United States)

    2010-05-04

    ... DEPARTMENT OF THE INTERIOR National Park Service Notice of Inventory Completion: Alaska State Office, Bureau of Land Management, Anchorage, AK; Museum of the Aleutians, Unalaska, AK; and University... Act (NAGPRA), 25 U.S.C. 3003, of the completion of an inventory of human remains and associated...

  16. Skeletal anchorage in orthodontics : A review of various systems in animal and human studies

    NARCIS (Netherlands)

    Janssen, Krista I.; Raghoebar, Gerry M.; Vissink, Arjan; Sandham, John

    2008-01-01

    Purpose: The aim of the present investigation was to review and evaluate the current literature on skeletal bone anchorage in orthodontics with regard to success rates of the various systems. Materials and Methods: MEDLINE, PubMed, and Cochrane searches (period January 1966 to January 2006, English

  17. Attitudes of orthodontists and laypersons towards tooth extractions and additional anchorage devices

    Directory of Open Access Journals (Sweden)

    Chidsanu Changsiripun

    2017-07-01

    Full Text Available Abstract Background This study investigated the attitudes of orthodontists and laypersons towards the choice of extracting second premolars, rather than first premolars, based on tooth condition and the use of additional anchorage devices. Methods Questionnaires were sent to two groups: 324 orthodontists who were members of the Thai Association of Orthodontists, and 100 randomly selected Thai laypersons aged above 20 years and who were unrelated to the field of dentistry. Descriptive and chi-square statistics were used to analyze the data. Results Questionnaires were returned by 142 orthodontists (43.8% and completed by 100 laypersons. The larger the size of the caries lesion in the maxillary second premolar was found, the more orthodontists and laypersons both chose to extract a carious maxillary second premolar instead of a healthy maxillary first premolar. For orthodontists, the use of mini-implant anchorage was significantly related to their extraction decision. Orthodontists who were familiar with mini-implants usage would choose to extract the second premolar at a lower size of extent of caries. Besides, when larger sizes of caries lesions in maxillary second premolars were considered, laypersons tended to have greater acceptance of the use of additional anchorage devices in order to keep the healthy maxillary first premolar. Conclusions In this study, tooth condition and the use of anchorage devices are currently the main considerations by both orthodontists and laypersons when selecting the teeth to be extracted for orthodontic treatment.

  18. Altered regulation of c-jun and its involvement in anchorage-independent growth of human lung cancers.

    Science.gov (United States)

    Maeno, K; Masuda, A; Yanagisawa, K; Konishi, H; Osada, H; Saito, T; Ueda, R; Takahashi, T

    2006-01-12

    The c-jun oncogene is frequently overexpressed in non-small-cell lung cancers (NSCLC), but its functional involvement in lung cancer development has not been clearly elucidated. In this study, we found that among the immediate-early serum responsible genes, exemplified by c-jun, c-fos and c-myc, induction of c-jun in a human bronchial epithelial cell line, BEAS-2B, was dependent on anchorage, in contrast to clear induction of c-fos and c-myc under both anchorage-dependent and -independent conditions. In fact, forced expression of c-jun in BEAS-2B cells significantly increased cell viability and colony formation in soft agar. Furthermore, we also found that such anchorage-dependent regulation of c-jun was lost in a significant fraction of human lung cancer cell lines. Interestingly, suppressed anchorage-independent but not anchorage-dependent growth was noted by constitutive expression of a dominant-negative c-jun mutant in a lung cancer cell line showing dysregulated and sustained c-jun expression in the absence of anchorage. These findings suggest that dysregulated c-jun expression may be involved in the acquisition of anchorage independence in the process of human lung carcinogenesis.

  19. Screw-type implants used as anchorage for lingual orthodontic mechanics: a case of bimaxillary protrusion with second premolar extraction.

    Science.gov (United States)

    Kawakami, Masayoshi; Miyawaki, Shouichi; Noguchi, Haruhiro; Kirita, Tadaaki

    2004-10-01

    We present a case of bialveolar protrusion treated with second premolar extraction. The patient did not agree to placement of a visible labial appliance or to the use of a headgear. Therefore, a lingual orthodontic appliance was used, and titanium screws were placed into the buccal alveolar bone for orthodontic absolute anchorage and support of en masse retraction of the anterior teeth. Cephalometric superimposition and panoramic radiographs showed little anchorage loss and good occlusion at the end of treatment. Our results suggest that lingual treatment combined with a screw-type implant anchorage provides reliable and comfortable results for those seeking invisible treatment.

  20. Herbst appliance with skeletal anchorage versus dental anchorage in adolescents with Class II malocclusion: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Batista, Klaus Barretto Dos Santos Lopes; Lima, Tatiana; Palomares, Nathália; Carvalho, Felipe de Assis; Quintão, Cátia; Miguel, José Augusto Mendes; Lin, Yin-Ling; Su, Ting-Li; O'Brien, Kevin

    2017-11-25

    The Herbst appliance is an orthodontic appliance that is used for the correction of class II malocclusion with skeletal discrepancies. Research has shown that this is effective. However, a potential harm is excessive protrusion of the lower front teeth. This is associated with gingival recession, loss of tooth support, and root resorption. This trial evaluates a method of reducing this problem. The study is a single-center, randomised, assessor-blinded, superiority clinical trial with parallel 1:1 allocation. Male and female young people (10-14 years old) with prominent front teeth (class II, division 1) will be treated in one orthodontic clinic. Group 1 will be treated with the conventional Herbst appliance with dental anchorage and group 2 with the Herbst appliance with indirect skeletal anchorage for 12 months. The primary objective will be to compare the proclination of the lower incisors between the Herbst appliance with dental anchorage and skeletal anchorage. Secondary objectives will be to evaluate the changes occurring between the groups in the mandible, maxilla, lower and upper molars, and in gingival recession and root resorption at the end of the treatment. Additionally, the young patient's experience using the appliances will be assessed. The primary outcome measure will be the amount of lower incisor proclination at the end of treatment. This will be assessed by cone-beam computed tomography (CBCT) superimposition. Secondary outcome measures will be the changes in the mandible, maxilla, lower and upper molars at the end of treatment assessed by tomography superimposition and the young patient's experience using the appliances assessed by self-reported questionnaires and semi-structured interviews. The randomisation method will be blocked randomisation, using software to generate a randomised list. The allocation concealment will be done in opaque envelopes numbered from 1 to 40 containing the treatment modality. The randomisation will be

  1. The benefit of differential moment concept in managing posterior anchorage and avoiding bite deepening

    Directory of Open Access Journals (Sweden)

    Harryanto Wijaya

    2012-09-01

    Full Text Available Background: Anchorage is one of the major concerns in orthodontic space closure. Various methods have been proposed to enhance posterior anchorage in space closure such as headgear, Nance holding appliance, and micro implant as temporary anchorage devices. However, several issues such as patient's compliance, appliance effectiveness, and cost of the device become many clinicians concern. The differential moment concept in segmented arch is a technique that requires no patient compliance but can effectively manage posterior anchorage and avoid bite deepening by careful application of forces and moments. Purpose: The purpose of this case report is to show the use of differential moment concept in segmented arch technique to manage posterior anchorage and to avoid bite deepening. Case: A 21 years old female patient with protrusive teeth as her chief complaint was treated using fixed orthodontic appliance. Case management: The treatment included four first bicuspid extraction and space closure utilizing differential moment concept in segmented arch. Conclusion: It can be concluded that application of differential moment concept in segmented arch technique is a non invasive, compliance independent, effective, and cost efficient method to manage posterior anchorage and to avoid bite deepening.latar belakang: Penjangkaran merupakan salah satu aspek yang sering kali menjadi masalah dalam penutupan ruang pada perawatan ortodonti. Berbagai metode disarankan untuk memperkuat penjangkaran posterior dalam penutupan ruang seperti headgear, piranti penahan Nance, dan implan mikro sebagai alat penjangkar sementara. Namun demikian, beberapa hal seperti kerjasama pasien, efektivitas piranti, dan biaya dari alat-alat tersebut sering menjadi perhatian/pertimbangan bagi klinisi. Konsep momen diferensial pada segmented arch adalah suatu cara yang efektif untuk memperkuat penjangkaran dan menghindari pendalaman gigitan tanpa memerlukan kerjasama pasien. tujuan

  2. 76 FR 39386 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage...

    Science.gov (United States)

    2011-07-06

    ... graduate and undergraduate marine biology students conducted approximately 600 hours of scientific... Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage Marine Terminal Redevelopment Project AGENCY: National Marine Fisheries Service, National Oceanic and Atmospheric Administration...

  3. 75 FR 38465 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage...

    Science.gov (United States)

    2010-07-02

    ..., from May 4 through November 18, 2009, trained graduate and undergraduate marine biology students... Importing Marine Mammals; Taking Marine Mammals Incidental to the Port of Anchorage Marine Terminal Redevelopment Project AGENCY: National Marine Fisheries Service, National Oceanic and Atmospheric Administration...

  4. Impedance-Based Cable Force Monitoring in Tendon-Anchorage Using Portable PZT-Interface Technique

    Directory of Open Access Journals (Sweden)

    Thanh-Canh Huynh

    2014-01-01

    Full Text Available In this paper, a portable PZT interface for tension force monitoring in the cable-anchorage subsystem is developed. Firstly, the theoretical background of the impedance-based method is presented. A few damage evaluation approaches are outlined to quantify the variation of impedance signatures. Secondly, a portable PZT interface is designed to monitor impedance signatures from the cable-anchorage subsystem. One degree-of-freedom analytical model of the PZT interface is established to explain how to represent the loss of cable force from the change in the electromechanical impedance of the PZT interface as well as reducing the sensitive frequency band by implementing the interface device. Finally, the applicability of the proposed PZT-interface technique is experimentally evaluated for cable force-loss monitoring in a lab-scaled test structure.

  5. Maxillary molar intrusion with zygomatic anchorage in open bite treatment: lateral and oblique cephalometric evaluation.

    Science.gov (United States)

    Oliveira, Talles Fernando Medeiros de; Nakao, Cecília Yuriko; Gonçalves, João Roberto; Santos-Pinto, Ary

    2015-03-01

    We aimed to use lateral and oblique radiographs to evaluate dental and skeletal changes arising from maxillary molar intrusion with zygomatic anchorage in open bite patients. We conducted a pilot study including nine patients (six females and three males; mean age, 18.7 ± 5.1 years) with skeletal open bite treated with titanium miniplates for posterior dentoalveolar intrusion. Lateral and oblique (right and left, 45°) radiographs were obtained before (T1) and 6 months after intrusion (T2). A paired t test was used for statistical evaluation. The maxillary posterior teeth were intruded 2.03 ± 0.87 mm (p open bite with skeletal anchorage provided intrusion of molars and counterclockwise rotation of the mandible, resulting in open bite closure.

  6. Patterned Anchorage to the Apical Extracellular Matrix Defines Tissue Shape in the Developing Appendages of Drosophila

    Science.gov (United States)

    Ray, Robert P.; Matamoro-Vidal, Alexis; Ribeiro, Paulo S.; Tapon, Nic; Houle, David; Salazar-Ciudad, Isaac; Thompson, Barry J.

    2015-01-01

    Summary How tissues acquire their characteristic shape is a fundamental unresolved question in biology. While genes have been characterized that control local mechanical forces to elongate epithelial tissues, genes controlling global forces in epithelia have yet to be identified. Here, we describe a genetic pathway that shapes appendages in Drosophila by defining the pattern of global tensile forces in the tissue. In the appendages, shape arises from tension generated by cell constriction and localized anchorage of the epithelium to the cuticle via the apical extracellular-matrix protein Dumpy (Dp). Altering Dp expression in the developing wing results in predictable changes in wing shape that can be simulated by a computational model that incorporates only tissue contraction and localized anchorage. Three other wing shape genes, narrow, tapered, and lanceolate, encode components of a pathway that modulates Dp distribution in the wing to refine the global force pattern and thus wing shape. PMID:26190146

  7. Indian Board of Orthodontics case report: Orthodontic management of vertical excess using skeletal anchorage

    Directory of Open Access Journals (Sweden)

    Ajit J Kalia

    2016-01-01

    Full Text Available B.B., a 21-year-old girl, presented with the chief complaint of forwardly placed upper front teeth and gummy smile. Diagnosis revealed prognathic maxilla and average mandible, Class II skeletal base with vertical growth pattern, end-on molars and Class II canine relationship bilaterally, convex profile, potentially incompetent lips, gummy smile, and protrusive lower lip. The patient′s treatment plan was extraction of all first bicuspids and retraction using temporary anchorage devices. Anchorage was reinforced using microimplants in the maxillary arch and second molar banding in the mandibular arch. The implants were placed high up in the vestibule to have more of an intrusive component and to reduce gummy smile at the end of the treatment.

  8. Horizontal lifelines - review of regulations and simple design method considering anchorage rigidity.

    Science.gov (United States)

    Galy, Bertrand; Lan, André

    2018-03-01

    Among the many occupational risks construction workers encounter every day falling from a height is the most dangerous. The objective of this article is to propose a simple analytical design method for horizontal lifelines (HLLs) that considers anchorage flexibility. The article presents a short review of the standards and regulations/acts/codes concerning HLLs in Canada the USA and Europe. A static analytical approach is proposed considering anchorage flexibility. The analytical results are compared with a series of 42 dynamic fall tests and a SAP2000 numerical model. The experimental results show that the analytical method is a little conservative and overestimates the line tension in most cases with a maximum of 17%. The static SAP2000 results show a maximum 2.1% difference with the analytical method. The analytical method is accurate enough to safely design HLLs and quick design abaci are provided to allow the engineer to make quick on-site verification if needed.

  9. Maxillary protraction using skeletal anchorage and intermaxillary elastics in Skeletal Class III patients

    OpenAIRE

    Esenlik, El?in; A?larc?, Cahide; Albayrak, Gayem Ero?lu; F?nd?k, Yavuz

    2015-01-01

    The aim of this case report is to describe the treatment of a patient with skeletal Class III malocclusion with maxillary retrognathia using skeletal anchorage devices and intermaxillary elastics. Miniplates were inserted between the mandibular lateral incisor and canine teeth on both sides in a male patient aged 14 years 5 months. Self-drilling mini-implants (1.6 mm diameter, 10 mm length) were installed between the maxillary second premolar and molar teeth, and Class III elastics were used ...

  10. Impedance monitoring at tendon-anchorage via mountable PZT interface and temperature-effect compensation

    Science.gov (United States)

    Huynh, Thanh-Canh; Nguyen, Tuan-Cuong; Choi, Sang-Hoon; Kim, Jeong-Tae

    2016-04-01

    In this study, the pre-stress force in pre-stressed concrete (PSC) girders is monitored via mountable PZT interface under varying temperature. Firstly, an impedance-based technique using mountable PZT interface is proposed for pre-stress-loss monitoring in tendon-anchorage systems. A cross correlation-based temperature-effect compensation algorithm using an effective frequency shift (EFS) of impedance signatures is visited. Secondly, lab-scale experiments are performed on a PSC girder instrumented with a mountable PZT interface at tendon-anchorage. A series of temperature variation and pre-stress-loss events are simulated for the lab-scale PSC girder. Thirdly, the feasibility of the mountable PZT interface for pre-stress-loss monitoring in tendon-anchorage is experimentally verified under constant temperature conditions. Finally, the PZT interface device is examined for pre-stress-loss monitoring under temperature changes to validate its applicability. The temperature effect on impedance signatures is compensated by minimizing cross-correlation deviation between impedance patterns of the mountable PZT interface.

  11. Lower incisor intrusion with intraoral transosseous stainless steel wire anchorage in rabbits.

    Science.gov (United States)

    Wu, Jian-chao; Huang, Ji-na; Lin, Xin-ping

    2010-06-01

    The purpose of this research was to investigate the potential use of intraoral transosseous stainless steel wires as anchorage for intrusion of the lower incisors using a rabbit model. Placement of intraoral transosseous stainless steel wires around incisors is similar to that of intraoral transosseous wiring of edentulous mandibular fractures. Ten male New Zealand rabbits, 9 +/- 1.5 months of age, average weight 1.8 +/- 0.3 kg, were used in this study. One lower incisor was intruded with a 50 g bilateral force using a coil spring for 10 weeks, while the other incisor served as the control. Clinical measurements of the distances between the occlusal edges of the incisors (EE) were performed weekly with a calliper. In addition to standard descriptive statistical calculations, a paired Student's t-test was used for comparison of the two groups. All surgical sites healed uneventfully after insertion of the wires. Significant differences were found in the change of EE between the experimental and control sides from 4 weeks onwards. Intrusion of the incisor, 4 +/- 0.58 mm, was seen on the test side, while EE on the control side remained unchanged. Within the limits of this animal study, it is concluded that the intraoral transosseous stainless steel wire anchorage system is a cost-effective method for intrusion of lower incisors when the use of other anchorage system is not possible.

  12. The Plurality of Harbors at Caesarea: The Southern Anchorage in Late Antiquity

    Science.gov (United States)

    Ratzlaff, Alexandra; Galili, Ehud; Waiman-Barak, Paula; Yasur-Landau, Assaf

    2017-08-01

    The engineering marvel of Sebastos, or Portus Augusti as it was called in Late Antiquity (284-638 CE), dominated Caesarea's harbor center along modern Israel's central coast but it was only one part of a larger maritime complex. The Southern Anchorage provides a case study as one portion of the Caesarea complex, as well as a node within the regional network of anchorages and small harbors. Ceramics recovered from here show a high percentage of locally, and provincially, produced storage jars engaged in maritime trade. The ceramic evidence points towards an intensified regional trade or cabotage rather than favouring long distance trade from large port to port. Working out of these small harbors, opportunities arose for greater flexibility in specialization of commodities and materials passing through the network of subsidiary ports, contributing to a more diversified market economy. This analysis provides another example in the growing focus on how these simple and semi-modified anchorages in the Eastern Mediterranean were often the predominant economic networks connecting hinterland and coastal trade.

  13. Skeletal anchorage for the correction of bimaxillary protrusion and gummy smile

    Directory of Open Access Journals (Sweden)

    P P Biswas

    2017-01-01

    Full Text Available Many methods of achieving maximum anchorage have been experimented by various clinicians through the years. Usage of mini implants has its own limitations, inconsistent results being the most common. However, anchorage using mini plates produced consistent results even though it requires a minor invasive surgical procedure. The aim was to retract and correct a gummy smile of 5 mm, diagnosed to be due to a vertical maxillary excess, with mini plates used bilaterally in the zygomatic buttress region. A modified “L” shaped surgical stainless steel mini plate was inserted and stabilized with 3 screws in the anterior region of the zygomatic buttress and sutured with the tip of the surgical plate exposed in the oral cavity for the attachment of an elastomeric chain to the arch wire. The gummy smile was fully corrected with minimal intrusion of maxillary anteriors. Cephalometrically, there was intrusion and retraction of maxillary incisors with absolutely no anchor loss. The modified surgical mini plate is an excellent tool for the successful correction of the gummy smile and also has proved to be a very efficient absolute anchorage system for en masse retraction.

  14. Anchorage of equipment - requirements and verification methods with emphasis on equipment of existing and constructed VVER-type nuclear power plants

    International Nuclear Information System (INIS)

    Masopust, R.

    1999-01-01

    Criteria and verification methods which are recommended for use in the capacity evaluation of anchorage of safety-related equipment at WWER-type nuclear power plants are presented. Developed in compliance with the relevant basic standards documents specifically for anchorage of WWER-type equipment components, the criteria and methods cover different types of anchor bolts and other anchorage elements which are typical of existing, constructed, or reconstructed WWER-type nuclear power plants

  15. Comparative evaluation of sagittal anchorage loss in lingual and labial appliances during space closure: A pilot study

    Directory of Open Access Journals (Sweden)

    Shivanand Venkatesh

    2015-01-01

    Full Text Available Aim: The purpose of this investigation was to assess and compare the anchorage loss between labial and lingual appliance systems during space closure. Materials and Methods: Twenty subjects were part of the study among which 10 subjects (mean age 21 ± 3.6 years were treated using lingual appliance system (0.018" slot-STb™ and 10 subjects (mean age 19 ± 6.1 years were treated using labial preadjusted edgewise appliance system (0.018" slot-MBT™ . First premolar extractions were performed to enable retraction of anterior teeth. Lateral cephalometric radiographs were taken at two intervals, before starting space closure and after space closure that were connoted as T0 and T1 and were analyzed using the method described by Pancherz to measure anchorage loss. Intraclass correlation coefficient (ICC was used to evaluate intraexaminer reliability of the measurements. Student′s t-test was performed to verify any statistical significant correlation between the labial and lingual appliance systems. Statistical differences were determined at the 95% confidence level (P < 0.05. Results: The results showed that all ICC for lingual and labial group were ≥0.90 showing good repeatability of the measurements. Mean anchorage loss of 1.238 ± 0.17 mm in lingual appliance system and an anchorage loss of 2.06 ± 0.39 mm occurred with the labial appliance system. On the comparison between the two appliance systems, lingual appliance demonstrated a significantly lesser anchorage loss than did the labial appliance. Interpretation and Conclusion: This prospective study concludes with the fact that lingual appliance provided better anchorage control than labial appliance during space closure. Use of lingual appliance could be considered in critical anchorage cases when compared with labial appliance.

  16. EFFECT OF END ANCHORAGE LENGTH AND STIRRUP RATIO ON BOND AND SHEAR CAPACITY OF CONCRETE BEAMS WITH NONMETALLIC REINFORCEMENT

    Directory of Open Access Journals (Sweden)

    RENDY THAMRIN

    2016-06-01

    Full Text Available This paper presents a study on the effect of end anchorage length and stirrup ratio on bond and shear capacity of concrete beams reinforced with Carbon Fiber Reinforced Polymer (CFRP bars. This study was carried out using test data on nine simply supported reinforced concrete beams with stirrups. The beams were subjected to two point monotonic loads and the test variables were the length of end anchorage and the stirrup ratio. Theoretical equations for calculating bond strength and shear capacity obtained from literature were applied and then compared with experimental values. Beams with inadequate end anchorage length showed premature bond failure even when there was sufficient stirrup ratio. Beams with adequate end anchorage length failed in shear or flexure modes depending on the stirrup ratio. A numerical model for bond stress and slip in response to pullout forces was also used to determine analytically the bond stress distributions along end anchorage. The behavior of tensile force acting on the stirrups was also examined. Finally, a simple model for predicting tension force acting on the stirrups was proposed.

  17. A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin.

    Directory of Open Access Journals (Sweden)

    Davide Danovi

    2010-07-01

    Full Text Available Anchorage-independent proliferation is a hallmark of oncogenic transformation and is thought to be conducive to proliferation of cancer cells away from their site of origin. We have previously reported that primary Schwann cells expressing the SV40 Large T antigen (LT are not fully transformed in that they maintain a strict requirement for attachment, requiring a further genetic change, such as oncogenic Ras, to gain anchorage-independence. Using the LT-expressing cells, we performed a genetic screen for anchorage-independent proliferation and identified Sensory and Motor Neuron Derived Factor (SMDF, a transmembrane class III isoform of Neuregulin 1. In contrast to oncogenic Ras, SMDF induced enhanced proliferation in normal primary Schwann cells but did not trigger cellular senescence. In cooperation with LT, SMDF drove anchorage-independent proliferation, loss of contact inhibition and tumourigenicity. This transforming ability was shared with membrane-bound class III but not secreted class I isoforms of Neuregulin, indicating a distinct mechanism of action. Importantly, we show that despite being membrane-bound signalling molecules, class III neuregulins transform via a cell intrinsic mechanism, as a result of constitutive, elevated levels of ErbB signalling at high cell density and in anchorage-free conditions. This novel transforming mechanism may provide new targets for cancer therapy.

  18. Effectiveness of interceptive treatment of class III malocclusions with skeletal anchorage: A systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Jorge Rodríguez de Guzmán-Barrera

    Full Text Available Recently, new strategies for treating class III malocclusions have appeared. Skeletal anchorage appears to reduce the dentoalveolar effects while maximising the orthopaedic effect in growing patients. The purpose of this systematic review and meta-analysis is to examine the effectiveness of bone anchorage devices for interceptive treatment of skeletal class III malocclusions. Searches were made in the Pubmed, Embase, Scopus and Cochrane databases, as well as in a grey literature database, and were complemented by hand-searching. The criteria for eligibility were: patients who had undergone orthodontic treatment with skeletal anchorage (miniplates and miniscrews. Patients with syndromes or craniofacial deformities or who had undergone maxillofacial surgery were excluded. The following variables were recorded for each article: author, year of publication, type of study, sample size, dropouts, demographic variables, treatment carried out, radiographic study (2D or 3D, follow-up time, and quality of the articles on the Newcastle-Ottawa Scale. The means and confidence intervals of the following variables were employed: Wits, overjet, ANB, SNA and SNB. Initially, 239 articles were identified. After removing the duplicates and applying the selection criteria, 9 were included in the qualitative synthesis and 7 in the quantitative synthesis (meta-analysis. It may be concluded that skeletal anchorage is an effective treatment for improving skeletal Class III malocclusion, but when compared with other traditional treatments such as disjunction and face mask, there is no clear evidence that skeletal anchorage improves the results.

  19. Clinical application of micro-implant anchorage in initial orthodontic retraction.

    Science.gov (United States)

    Wahabuddin, Shaji; Mascarenhas, Rohan; Iqbal, Mahamad; Husain, Akhter

    2015-02-01

    Micro-implant is a device that is temporarily fixed to bone for the purpose of enhancing orthodontic anchorage either by supporting the teeth of the reactive unit or by obviating the need for the reactive unit altogether, and which is subsequently removed after use. The purpose of this study was to evaluate the clinical efficiency of micro-implants in reinforcing anchorage during the initial retraction of anterior teeth, check the rate of initial retraction for 8 weeks, and assess the stability of micro-implants during this period. Eighteen micro-implants were placed (10 in the maxilla and 8 in the mandible) and immediately loaded with 200-250 g of force using 9-mm closed coil Nitinol springs. The amount of space closure was measured every 2 weeks until the eighth week. Cephalometric measurements were made at the end of the study to evaluate anchor loss, if any. Micro-implant stability was also assessed. The rate of initial retraction in the maxilla at the end of 8 weeks was 1.65 mm/quadrant and 1.51 mm/quadrant in the mandible. The amount of retraction on the left side of the arches was 1.66 mm/quadrant and 1.49 mm/quadrant on the right side. The average initial retraction for both arches per month was 0.78 mm. An anchor loss of 0.1 mm (0.06%) was observed in the maxilla while no mandibular anchor loss was recorded. The rate of initial retraction observed in the maxilla was more than that achieved in the mandible. Initial retraction was also more on the left side of the arches. There was no anchor loss in the mandible. The micro-implant-reinforced anchorage was helpful in minimizing anchor loss and accepted heavy traction forces but did not bring about a faster rate of retraction.

  20. A prospective comparative study between differential moments and miniscrews in anchorage control.

    Science.gov (United States)

    Davoody, Amirparviz R; Posada, Laura; Utreja, Achint; Janakiraman, Nandakumar; Neace, William P; Uribe, Flavio; Nanda, Ravindra

    2013-10-01

    The purpose of this study was to measure the efficacy of anchorage control between differential moments mechanics and temporary anchorage devices in a clinical trial. Forty-six patients requiring extraction of maxillary first premolars were allocated into 2 treatment groups. The differential moments group (G1) received a nickel titanium (NiTi) intrusion arch and a 150g NiTi closing coil spring for separate canine retraction, followed by a continuous mushroom loop archwire for the retraction of the incisors. The TAD group (G2) received one miniscrew placed between maxillary second premolars and first molars with a 150 g NiTi closing coil spring connecting the miniscrew to a hook placed in the archwire between the lateral incisor and canine. Lateral cephalograms were taken before (T1) and after incisor retraction (T2). The ratio of molar protraction to incisor retraction was calculated and intragroup and intergroup changes in upper lip, maxillary incisor and molar position were analyzed by paired and independent t-tests. Twenty-eight patients were analyzed after 18 patients did not receive the intervention, were lost to follow-up, or discontinued treatment. The ratio of molar protraction to incisor retraction in G1 was 0.44 and in G2 was -0.11, which was significantly different. There was a statistically significant change in upper lip from T1 to T2 but no difference between the two groups. Moreover, there was a significant distal molar tipping and lingual incisor tipping in G2. There is a significant difference in the amount of anchorage control using differential moments mechanics compared to TADs. Although statistically significant retraction of upper lip was observed in both groups, there was no significant difference between the two groups.

  1. Seismic Margin Assessment and Reinforcement of Safety-Related Equipment Considering its Anchorage Degradation

    International Nuclear Information System (INIS)

    Choi, Ho-Sam; Jung, Dong-Yeoul

    2012-01-01

    This paper describes the overall approach and review results of the Seismic Margin Assessment (SMA) for safety-related equipment considering anchorage degradation. The equipment seismic reinforcement performed following the SMA review results is also described. The SMA review was based on the methodology in EPRI Reports NP-6041 and NP-7498, and it was conducted using the data obtained from the USI A-46 seismic evaluation. The seismic margin earthquake selected for SMA review was based on the recommendations in EPRI NP-6041 and NUREG-1407, and it has a peak ground acceleration (PGA) of 0.3g. (author)

  2. Correction of gummy smile in a patient of vertical maxillary excess using absolute anchorage system

    Directory of Open Access Journals (Sweden)

    Ekta Lahoti

    2018-01-01

    Full Text Available This article presents the orthodontic treatment of a 24-year-old female patient with gummy smile and proclination along with a hyperdivergent profile. The patient showed excessive gingival display in both the anterior and posterior areas in the maxilla. Such situation in an adult patient often demands surgical therapy. However, due to patient reluctance toward surgery, the gummy smile was treated by the intrusion of the whole maxillary arch. After alignment and leveling, absolute anchorage system as well as a modified transpalatal arch was designed to achieve posterosuperior movement of the entire upper dentition. The active treatment period was 2.3 years.

  3. [Intruding upper incisors using mini-screw anchorage in patients with gummy smile].

    Science.gov (United States)

    Li, Yun-Yi; Zhou, Yan-Heng; Lin, Jiu-Xiang

    2009-08-01

    To evaluate the effectiveness of mini-screw anchorage on intruding upper incisors in patients with gummy smile. Sixteen female patients (mean age: 23.8 years) were involved in this study. The mini-screws were placed between upper lateral incisors and canines on both sides for intruding upper incisors together with fixed appliance. The cephalometric analysis was carried out. Totally 63 teeth in 16 patients were intruded successfully and the deep overbite was decreased by (2.74 +/- 2.00) mm (P gummy smile by intruding upper incisors with mini-screw implant.

  4. Mini-implants as provisional anchorage for the replacement of missing anterior teeth: a clinical report.

    Science.gov (United States)

    Gurgel, Júlio A; Tavarez, Rudys R; Ursi, Weber J; Neves, Murilo G; Bramante, Fausto S; Pinzan-Vercelino, Célia R M

    2014-10-01

    This clinical report describes an adult patient referred for orthodontic treatment with mini-implants as anchorage to correct the root angulation of maxillary lateral incisors. The purpose of this report was to demonstrate the versatility of mini-implants placed in a vertical direction in esthetic areas. During orthodontic treatment, some aspects must be observed to preserve the interim restoration against the occlusal loads to avoid screw fracture. A fixed appliance was placed to correct the position of the maxillary anterior teeth and to complete the treatment. Acceptable esthetics and function were achieved. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  5. Randomized clinical trial comparing control of maxillary anchorage with 2 retraction techniques.

    Science.gov (United States)

    Xu, Tian-Min; Zhang, Xiaoyun; Oh, Hee Soo; Boyd, Robert L; Korn, Edward L; Baumrind, Sheldon

    2010-11-01

    The objective of this pilot randomized clinical trial was to investigate the relative effectiveness of anchorage conservation of en-masse and 2-step retraction techniques during maximum anchorage treatment in patients with Angle Class I and Class II malocclusions. Sixty-four growing subjects (25 boys, 39 girls; 10.2-15.9 years old) who required maximum anchorage were randomized to 2 treatment techniques: en-masse retraction (n = 32) and 2-step retraction (n = 32); the groups were stratified by sex and starting age. Each patient was treated by a full-time clinic instructor experienced in the use of both retraction techniques at the orthodontic clinic of Peking University School of Stomatology in China. All patients used headgear, and most had transpalatal appliances. Lateral cephalograms taken before treatment and at the end of treatment were used to evaluate treatment-associated changes. Differences in maxillary molar mesial displacement and maxillary incisor retraction were measured with the before and after treatment tracings superimposed on the anatomic best fit of the palatal structures. Differences in mesial displacement of the maxillary first molar were compared between the 2 treatment techniques, between sexes, and between different starting-age groups. Average mesial displacement of the maxillary first molar was slightly less in the en-masse group than in the 2-step group (mean, -0.36 mm; 95% CI, -1.42 to 0.71 mm). The average mesial displacement of the maxillary first molar for both treatment groups pooled (n = 63, because 1 patient was lost to follow-up) was 4.3 ± 2.1 mm (mean ± standard deviation). Boys had significantly more mesial displacement than girls (mean difference, 1.3 mm; P <0.03). Younger adolescents had significantly more mesial displacement than older adolescents (mean difference, 1.3 mm; P <0.02). Average mesial displacement of the maxillary first molar with 2-step retraction was slightly greater than that for en-masse retraction, but the

  6. 3D Retraction Force Vector Indicator for Anterior en masse Retraction with Miniscrew Anchorage

    Directory of Open Access Journals (Sweden)

    Pavankumar Janardan Vibhute

    2012-01-01

    Full Text Available Miniscrews are used for providing anchorage in orthodontics and have become an integral part in the orthodontic treatment of severely protrusive patients for maximum retraction of anterior teeth after premolar extractions. Often the miniscrews are placed according to the availability of safe zone, interradicular clearance and type of mucosa. Sometime loosening and failure of miniscrew and reinsertion with change in site lead to asymmetry in positioning. This uneven positioning of miniscrew imposes unbalanced biomechanics in the same jaw. Force vectors of space closing auxiliary spring differs on both side and causes disturbance in occlusion or asymmetry in arch form. This article shows how ′3D force vector indicator′ can be used to overcome the problems arise due to asymmetric retraction forces with miniscrew anchorage. This technique measures and specifies the correct location of implant head, i.e. 3D position of the posterior point of attachment for retraction auxiliary and its direction of vector with respect to the fixed appliance and the underlying dentition.

  7. Urban encroachment on the wilderness: moose-vehicle collisions in Anchorage, Alaska, 1991-1995.

    Science.gov (United States)

    Garrett, L C; Conway, G A

    1998-01-01

    Moose have successfully adapted to urban sprawl in Anchorage, Alaska, using greenbelt areas for shelter, forage, and protection. However, the proximity of moose to people poses unique hazards: a collision with a moose may cause significant injury and vehicle damage. Moose-vehicle collisions were identified using Municipality of Anchorage records. Completeness of reporting was assessed from Alaska Department of Fish and Game records. The moose-vehicle collision rate increased significantly from 38 to 49.2/100,000/yr during the study period (p = .005, x2 = 7.795). Of 519 reported moose-auto collisions, 120 (23%) resulted in injury to 158 people, with no human fatalities. Most collisions (291 or 56%) occurred between 1800 and 0200 hours; 411 (79%) occurred after dark; 154 (30%) occurred during December and January; and slick road conditions were identified in 280 (54%) incidents. Incidents occurred primarily near greenbelt areas. Moose-vehicle collisions often occur at night, on unlighted, slick road surfaces. Moose-vehicle collisions may be prevented by: reducing speed limits around green-belt areas, brighter vehicle headlights, placement of street lights in known moose areas, underpasses for wildlife at known crossings, and snow removal to reduce berm height in known moose areas.

  8. Menentukan Besar Anchorage Loss Gigi Molar Pertama Atas pada Model Studi

    Directory of Open Access Journals (Sweden)

    Suhardi Suhardi

    2015-09-01

    Full Text Available Anchorage loss may frequently be found on the first upper molar during orthodontic treatment, especially while canines are retracted. There are several means used to determine whether anchorage loss has occurred, i.e. radiographically by cephalometric tracing, and clinically by measuring some point of references on the study model. There are many variables available on the study model used as point of references, i.e. anterior and posterior palatal raphe, the third medial rugae point, and mesial and distal points of the first molar. Use as points and lines references are the third medial rugae points and the line drawn between the anterior and posterior raphe point (the median palatal raphe line. THe linear measurement drawn from the mesial point of first molar and the thir medial rugae point perpendicular to the median palatal raphe line are utilized to determine the intensity meovement could be determined by measuring the angle of line drawn from mesial and distal point of the first molar to the median palatal raphe line.

  9. The "Real Self" and Inauthenticity: The Importance of Self-Concept Anchorage for Emotional Experiences in the Workplace

    Science.gov (United States)

    Sloan, Melissa M.

    2007-01-01

    I examine the utility of self-concept anchorage (as described by Turner 1976) in the analysis of inauthenticity in the workplace. As controlling internally felt emotion may distance the worker from her true feelings or true self, the management of emotion in the workplace can produce feelings of inauthenticity in the worker. This relationship has…

  10. 33 CFR 110.236 - Pacific Ocean off Barbers Point, Island of Oahu, Hawaii: Offshore pipeline terminal anchorages.

    Science.gov (United States)

    2010-07-01

    ..., Island of Oahu, Hawaii: Offshore pipeline terminal anchorages. 110.236 Section 110.236 Navigation and... Grounds § 110.236 Pacific Ocean off Barbers Point, Island of Oahu, Hawaii: Offshore pipeline terminal... shall notify the Captain of the Port, Honolulu, Hawaii, and the Commanding Officer, U.S. Naval Air...

  11. A mixed-methods approach for analysing social support and social anchorage of single mothers’ personal networks

    NARCIS (Netherlands)

    Lumino, Rosaria; Ragozini, Giancarlo; van Duijn, Marijtje; Vitale, Maria Prosperina

    2017-01-01

    The present paper analyses the relationship among social support and personal networks by focusing on social anchorage, which is a specific dimension of social support conveying to what extent people feel integrated into their personal networks. Specifying when, why, and how personal relationships

  12. Orthodontic treatment of gummy smile by maxillary total intrusion with a midpalatal absolute anchorage system.

    Science.gov (United States)

    Hong, Ryoon-Ki; Lim, Seung-Min; Heo, Jung-Min; Baek, Seung-Hak

    2013-06-01

    This article describes the orthodontic treatment of a 31-year-old Korean female patient with gummy smile and crowding. The patient showed excessive gingival display in both the anterior and posterior areas and a large difference in gingival heights between the anterior and posterior teeth in the maxilla. To correct the gummy smile, we elected to intrude the entire maxillary dentition instead of focusing only on the maxillary anterior teeth. Alignment and leveling were performed, and a midpalatal absolute anchorage system as well as a modified lingual arch was designed to achieve posterosuperior movement of the entire upper dentition. The active treatment period was 18 months. The gummy smile and crowding were corrected, and the results were stable at 21 months post-treatment.

  13. Success rates and factors associated with failure of temporary anchorage devices: A prospective clinical trial.

    Science.gov (United States)

    Aly, Shehab A; Alyan, Doha; Fayed, Mona S; Alhammadi, Maged S; Mostafa, Yehya A

    2018-03-06

    The objective of the present study was to investigate success rates and associated factors affecting temporary anchorage device (TAD) failure in different biomechanical applications. A total of 180 TADs were used as a part of 82 patients' treatment plan (24 males and 58 females); their mean age was 21.41 years. Three types of TADs were used: 50 (3M ESPE, Neuss, Germany), 56 (Bone screw; Jeil Medical, Seoul, Korea), and 74 (Morelli, Sorocaba, Brazil). Eight maxillary and four mandibular sites were selected for insertion. Three different lengths (6, 8, and 10 mm) and three different diameters (1.5, 1.6, and 1.8 mm) were used. The force levels were set at 50, 100, 150, 200, and 250 g. Patient-, implant-, and operator-dependent factors were evaluated throughout the 266 days of function. Qualitative variables were described by proportions and percentages and analyzed using χ 2 test. The overall success rate was 82.2%. The higher age group showed a significantly higher success rate. Oral hygiene showed a statistically-significant (P ˂ .05) difference between both success and failure groups. All other patient-related factors showed no significant differences. Regarding force levels used, the highest success rate was in 250 g and the lowest was in 100 g. There were no significant differences between both groups regarding other implant- and operator-related factors. Temporary anchorage devices have a good success rate and are beneficial to be integrated in orthodontic treatment planning. Patient age, oral hygiene, and force level are the most significant factors affecting TAD success. © 2018 John Wiley & Sons Australia, Ltd.

  14. Management of severe anterior open-bite in an adult patient using miniscrews as skeletal anchorage.

    Science.gov (United States)

    Rachala, Madhukar Reddy; Harikrishnan, Pandurangan

    2010-01-01

    Anterior open bite is often caused by a downward rotation of the mandible and/or by excessive eruption of the posterior teeth. In such cases, it is difficult to establish absolute anchorage for molar intrusion by traditional orthodontic mechanics. This is a case report of successful treatment of a severe anterior open bite using miniscrew anchorage. A female patient of 20 yrs presented with symmetrical frontal facial appearance, increased anterior facial height, convex profile and incompetent lips. Dentally, she had lost both mandibular first molars due to caries and both maxillary first molars were extruded. She had class II canine relationship, 5 mm overjet, 5 mm anterior open bite, 3 mm mandibular midline diastema and a spacing of 2 mm in the maxillary arch. The treatment objectives were to correct the anterior open bite and establish ideal overjet and overbite and to restore the mandibular first molars with fixed prosthesis. Titanium miniscrews (1.3 mm diameter and 9 mm length) were implanted bilaterally in the maxillary arch between the second premolar and the first molar, and an intrusion force was applied with NiTi closed coil springs for 8 months. After molar intrusion, the same screws were used for en masse retraction of the entire dentition (third molars were extracted) for 4 months. The results showed that, after an active treatment of 20 months, the maxillary molars were intruded about 4 mm each and good occlusion was achieved. In conclusion, the miniscrews were very useful in the non-surgical management of adult anterior open bite cases.

  15. Revisiting the stability of mini-implants used for orthodontic anchorage.

    Science.gov (United States)

    Yao, Chung-Chen Jane; Chang, Hao-Hueng; Chang, Jenny Zwei-Chieng; Lai, Hsiang-Hua; Lu, Shao-Chun; Chen, Yi-Jane

    2015-11-01

    The aim of this study is to comprehensively analyze the potential factors affecting the failure rates of three types of mini-implants used for orthodontic anchorage. Data were collected on 727 mini-implants (miniplates, predrilled titanium miniscrews, and self-drilling stainless steel miniscrews) in 220 patients. The factors related to mini-implant failure were investigated using a Chi-square test for univariate analysis and a generalized estimating equation model for multivariate analysis. The failure rate for miniplates was significantly lower than for miniscrews. All types of mini-implants, especially the self-drilling stainless steel miniscrews, showed decreased stability if the previous implantation had failed. The stability of predrilled titanium miniscrews and self-drilling stainless steel miniscrews were comparable at the first implantation. However, the failure rate of stainless steel miniscrews increased at the second implantation. The univariate analysis showed that the following variables had a significant influence on the failure rates of mini-implants: age of patient, type of mini-implant, site of implantation, and characteristics of the soft tissue around the mini-implants. The generalized estimating equation analysis revealed that mini-implants with miniscrews used in patients younger than 35 years, subjected to orthodontic loading after 30 days and implanted on the alveolar bone ridge, have a significantly higher risk of failure. This study revealed that once the dental surgeon becomes familiar with the procedure, the stability of orthodontic mini-implants depends on the type of mini-implant, age of the patient, implantation site, and the healing time of the mini-implant. Miniplates are a more feasible anchorage system when miniscrews fail repeatedly. Copyright © 2014. Published by Elsevier B.V.

  16. Assessment of changes following en-masse retraction with mini-implants anchorage compared to two-step retraction with conventional anchorage in patients with class II division 1 malocclusion: a randomized controlled trial.

    Science.gov (United States)

    Al-Sibaie, Salma; Hajeer, Mohammad Y

    2014-06-01

    No randomized controlled trial has tried to compare treatment outcomes between the sliding en-masse retraction of upper anterior teeth supported by mini-implants and the two-step sliding retraction technique employing conventional anchorage devices. To evaluate skeletal, dental, and soft tissue changes following anterior teeth retraction. Parallel-groups randomized controlled trial on patients with class II division 1 malocclusion treated at the University of Al-Baath Dental School in Hamah, Syria between July 2011 and May 2013. One hundred and thirty-three patients with an upper dentoalveolar protrusion were evaluated and 80 patients fulfilled the inclusion criteria. Randomization was performed using computer-generated tables; allocation was concealed using sequentially numbered opaque and sealed envelopes. Fifty-six participants were analysed (mean age 22.34 ± 4.56 years). They were randomly distributed into two groups with 28 patients in each group (1:1 allocation ratio). Following first premolar extraction, space closure was accomplished using either the en-masse technique with mini-implants or the two-step technique with transpalatal arches (TPAs). The antero-posterior displacements of upper incisal edges and upper first molars were measured on lateral cephalograms at three assessment times. Assessor blinding was employed. A bodily retraction (-4.42 mm; P mini-implants group, whereas upper anterior teeth retraction was achieved by controlled palatal tipping in the TPA group. When retracting anterior teeth in patients with moderate to severe protrusion, the en-masse retraction based on mini-implants anchorage gave superior results compared to the two-step retraction based on conventional anchorage in terms of speed, dental changes, anchorage loss, and aesthetic outcomes.

  17. Bio-cultural anchorage of the prickly pear cactus in Tlalnepantla (Morelos, Mexico

    Directory of Open Access Journals (Sweden)

    Torres-Salcido, Gerardo

    2016-06-01

    Full Text Available The prickly pear cactus is a source of food with strong bio-cultural anchorage in Mexico. This is due to at least three factors: 1 the nature and heritage of cacti; 2 cultural heritage; and 3 the socio-cultural relationships with historical and symbolic roots that have facilitated knowledge of how to cultivate it and how to use it. The aim of this article is to put factors of territorial anchorage and its historical transformation in context by examining the case of the municipality of Tlalnepantla in the state of Morelos, Mexico. This community has experienced accelerated change due to the exchange of traditional crops for the prickly pear cactus and the integration of farming, commercialization and agro-transformation. Our hypothesis is that the market, internal conflicts and a lack of socio-institutional coordination have put social organization into crisis, favoring the territorial spread of the prickly pear cactus and making the Local Agro-Food Systems (LAFS of Tlalnepantla less competitive. The conclusions highlight important economic and social advances whose roots lie in the strengthening and anchorage of the territory-product. However, circumstances both internal and external to the community persist, such as intra-community conflicts, the international market and cultural paradigm shifts that affect the producers and put consolidation of the LAFS at risk.El nopal es un alimento con un fuerte anclaje bio-cultural en México, propiciado por al menos tres factores: 1 la naturaleza y el patrimonio de cactáceas; 2 el patrimonio cultural; y, 3 las relaciones socio-culturales que han permitido un “saber hacer” y un “saber utilizar” con raíces históricas y simbólicas. El objetivo es situar los factores de anclaje territorial y su transformación histórica tomando como caso el municipio de Tlalnepantla, en el estado de Morelos, México. Esta comunidad ha experimentado un acelerado cambio por la reconversión de los cultivos

  18. Skeletal anchorage for intrusion of bimaxillary molars in a patient with skeletal open bite and temporomandibular disorders.

    Science.gov (United States)

    Iwasa, Akihiko; Horiuchi, Shinya; Kinouchi, Nao; Izawa, Takashi; Hiasa, Masahiro; Kawai, Nobuhiko; Yasue, Akihiro; Hassan, Ali H; Tanaka, Eiji

    2017-01-01

    The treatment of severe skeletal anterior open bite is extremely difficult in adults, and orthognathic surgery is generally selected for its treatment. We report the case of an 18-year-old adult patient with skeletal anterior open bite and temporomandibular disorders who was successfully treated using temporary anchorage devices. She had an open bite of -2.0 mm and an increased facial height. Miniplates were implanted in both the maxilla and mandible, and molar intrusion resulted in counterclockwise rotation of the mandible over a period of 12 months. After active treatment, her upper and lower first molars were intruded by approximately 2 mm and her overbite became +2.5 mm. Her retrognathic profile improved with counterclockwise rotation of the mandible. Orthodontic treatment aided with skeletal anchorage is beneficial for intrusion of bimaxillary molars in patients with anterior open bite.

  19. The U.S. Department of Energy Office of Indian Energy Policy and Programs, Anchorage, Alaska, Roundtable Summary

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-04-14

    The Anchorage, Alaska Roundtable on Tribal Energy Policy convened at 10:00 a.m., Thursday April 15th, at the downtown Anchorage Hilton. The meeting was held by the Department of Energy (DOE) Office of Indian Energy Policy and Programs (Office of Indian Energy). Tracey LeBeau, Director of the Office of Indian Energy, and Pilar Thomas, Deputy Director-Policy of the Office of Indian Energy, represented DOE. Approximately twenty-seven people attended the meeting, including representatives of three native Alaskan villages, four Alaskan tribal corporations representing more than 40 tribal governments, as well as representatives from tribal associations and conferences. Interested state, federal, and non-profit representatives also were present. A full list of attendees is at the end of this summary. The meeting was facilitated by the Udall Foundation’s U.S. Institute for Environmental Conflict Resolution (U.S. Institute).  

  20. Metallurgical Behavior of Ti-6Al-4V Alloy Mini-Implants as a Temporary Anchorage Device in Orthodontics Applications

    Directory of Open Access Journals (Sweden)

    Mendoza-Bravo Ivan

    2014-01-01

    Full Text Available The application of mini implants as a temporary anchorage device in orthodontics is a new technique that allows the movement of teeth in an efficient and predictable way. Although they have started to be used in Germany, Japan and South Korea, there is still the need to analyze and diffuse the advantages this procedure can offer over the traditional techniques. The objective of this research work was to analyze the integrity of Ti-6Al-4V mini implants temporary employed for 4 months on three patients as an anchorage device. The mini implants were analyzed by means of electron scanning microscopy in order to determine superficial and microstructural changes as well as the interaction with human tissue. Results showed the presence of wear on the thread zone caused during the insertion into the maxilar bone. The adherence of organic tissue was also observed on two mini-implants.

  1. Temporary anchorage devices (TADs) in orthodontics: review of the factors that influence the clinical success rate of the mini-implants.

    Science.gov (United States)

    Leo, M; Cerroni, L; Pasquantonio, G; Condò, S G; Condò, R

    2016-01-01

    The mini-implant, temporary anchorage devices (TADS), are now a common method of treatment in Orthodontics with versatility, minimal invasiveness and the relationship between costs and benefits that they offer even today. Skeletal anchorage has, to a large degree, replaced conventional anchorage in situations where anchorage is considered either critical, insufficient, or likely to result in undesirable side effects such as vertical displacements generated by inter-maxillary force systems. The objective of this study is to carry out a review about the factors that seem affect the success or failure rate of orthodontic mini-implants. A computerized literature review was performed by searching the MEDLINE database (Entrez PubMed, www.ncbi.nlm.nih.gov), Google Scholar, Scopus, Cochrane Central Register of Controlled Trials, Isi Web of Knowledge until March 2016 . The main subject heading "orthodontics" was combined with these keywords mini-implant, mini-screw, micro-implants, mini-implant success rate, mini-implant failure rate, skeletal anchorage, temporary anchorage device (TADS). In the selection process, abstracts were initially read independently by two researchers to identify potentially eligible full text papers which were then retrieved and assessed in order to decide on the final inclusion. The clinical success of orthodontic anchorage by mini-implants depends on the stability of the miniscrews used for fixation. For good stability, the application site must provide bone of good quantity and quality. We can reasonably assume that the stability of the anchorage of the mini-implants could be optimized by selecting a position with particular characteristics of quality and quantity of bone, in relation to cortical and total mandibular and jaw bone thickness. These expected informations are important because they indicates that the bone quality and quantity are significant when considering an implant placement site, but also that there are other confounding

  2. Treatment Effects of Occipitomental Anchorage Appliance of Maxillary Protraction Combined with Chincup Traction in Children with Class III Malocclusion

    OpenAIRE

    Hsiang-Chien Lin; Hong-Po Chang; Hsin-Fu Chang

    2007-01-01

    Little information related to the treatment effects of the occipitomental anchorage (OMA) appliance of maxillary (Mx) protraction combined with chincup traction is available. The aim of this study was to investigate the treatment effects of the OMA orthopedic appliance on patients with Class III malocclusion. Methods: Pretreatment and post-treatment cephalometric records of 20 consecutively treated patients with Class III malocclusions were evaluated and compared with a matched sample of u...

  3. Effect of molar intrusion with temporary anchorage devices in patients with anterior open bite: a systematic review

    OpenAIRE

    Ahmad Saleem Alsafadi; Mohannad M. Alabdullah; Humam Saltaji; Anas Abdo; Mohamed Youssef

    2016-01-01

    Abstract Objective The objective of the study is to assess the effect of molar intrusion with temporary anchorage devices on the vertical facial morphology and mandibular rotation during open bite treatment in the permanent dentition. Methods We performed a systematic review of the published data in seven electronic databases up to September 2015. We considered studies for inclusion if they were examining the effects of posterior teeth intrusion on the vertical facial morphology with open bit...

  4. Modified Adherence Method (MAM) for Electrofusion of Anchorage-Dependent Cells.

    Science.gov (United States)

    Ušaj, Marko; Kandušer, Maša

    2015-01-01

    The artificially induced cell fusion is a useful experimental tool in biology, biotechnology and medicine. The electrofusion is a physical method for cell fusion that applies high-voltage electric pulses. The use of electric pulses causes cell membrane structural changes which bring the cell membrane in the so-called fusogenic state. When such fusogenic membranes are in close contact cell fusion takes place. Physical contact between fusion partners can be achieved by various methods and one of them is modified adherence method (MAM) described in detail here on B16-F1 cell line. The method is based on the fact that living cells form contacts in confluent culture. However, instead of using confluent cell culture, in modified adherence method cells are plated in suitable concentration and allowed to form contacts for only short predetermined period of time. During that time the cells are only slightly attached to the dish surface maintaining the spherical shape. Observed high fusion yields up to 50 % obtained by MAM in situ by dual-color fluorescence microscopy are among the highest in field of electrofusion. The method can be readily adapted to other anchorage-dependent cell lines.

  5. Bilateral en-masse distalization of maxillary posterior teeth with skeletal anchorage: a case report

    Directory of Open Access Journals (Sweden)

    Saeed Noorollahian

    Full Text Available ABSTRACT Objective: The aim of this study was to introduce a new method for bilateral distal movement of the entire maxillary posterior segment. Case report: A 17-year-old girl with Class I skeletal malocclusion (end-to-end molar relationships, deviated midline and space deficiency for left maxillary canine was referred for orthodontic treatment. She did not accept maxillary first premolars extraction. A modified Hyrax appliance (Dentaurum Ispringen, Germany was used for bilateral distalization of maxillary posterior teeth simultaneously. Expansion vector was set anteroposteriorly. Posterior legs of Hyrax were welded to first maxillary molar bands. All posterior teeth on each side consolidated with a segment of 0.017 × 0.025-in stainless steel wire from the buccal side. Anterior legs of Hyrax were bent into eyelet form and attached to the anterior palate with two mini-screws (2 × 10 mm (Jeil Medical Corporation Seoul, South Korea. Hyrax opening rate was 0.8 mm per month. Lateral cephalometric radiographs were used to evaluate the extent of distal movement. 3.5-mm distalization of posterior maxillary teeth was achieved in five months. Results: A nearly bodily distal movement without anchorage loss was obtained. Conclusion: The mini-screw-supported modified Hyrax appliance was found to be helpful for achieving en-masse distal movement of maxillary posterior teeth.

  6. Pedicle screw anchorage of carbon fiber-reinforced PEEK screws under cyclic loading.

    Science.gov (United States)

    Lindtner, Richard A; Schmid, Rene; Nydegger, Thomas; Konschake, Marko; Schmoelz, Werner

    2018-03-01

    Pedicle screw loosening is a common and significant complication after posterior spinal instrumentation, particularly in osteoporosis. Radiolucent carbon fiber-reinforced polyetheretherketone (CF/PEEK) pedicle screws have been developed recently to overcome drawbacks of conventional metallic screws, such as metal-induced imaging artifacts and interference with postoperative radiotherapy. Beyond radiolucency, CF/PEEK may also be advantageous over standard titanium in terms of pedicle screw loosening due to its unique material properties. However, screw anchorage and loosening of CF/PEEK pedicle screws have not been evaluated yet. The aim of this biomechanical study therefore was to evaluate whether the use of this alternative nonmetallic pedicle screw material affects screw loosening. The hypotheses tested were that (1) nonmetallic CF/PEEK pedicle screws resist an equal or higher number of load cycles until loosening than standard titanium screws and that (2) PMMA cement augmentation further increases the number of load cycles until loosening of CF/PEEK screws. In the first part of the study, left and right pedicles of ten cadaveric lumbar vertebrae (BMD 70.8 mg/cm 3  ± 14.5) were randomly instrumented with either CF/PEEK or standard titanium pedicle screws. In the second part, left and right pedicles of ten vertebrae (BMD 56.3 mg/cm 3  ± 15.8) were randomly instrumented with either PMMA-augmented or nonaugmented CF/PEEK pedicle screws. Each pedicle screw was subjected to cyclic cranio-caudal loading (initial load ranging from - 50 N to + 50 N) with stepwise increasing compressive loads (5 N every 100 cycles) until loosening or a maximum of 10,000 cycles. Angular screw motion ("screw toggling") within the vertebra was measured with a 3D motion analysis system every 100 cycles and by stress fluoroscopy every 500 cycles. The nonmetallic CF/PEEK pedicle screws resisted a similar number of load cycles until loosening as the contralateral standard

  7. Quantity and quality of urban storm runoff from the Chester Creek basin Anchorage, Alaska

    Science.gov (United States)

    Brabets, T.P.

    1987-01-01

    Urbanization has affected both the flow characteristics and water quality of streams in the Chester Creek basin, of Anchorage, Alaska. Peak flows are higher in the urban rather than rural parts of the basin, and the percent of effective impervious area has a significant effect on storm runoff volumes and peaks. Water quality in the Chester Creek basin varies according to season and flow conditions. During low or base-flow conditions, concentrations of most water quality constituents measured are within State of Alaska drinking water standards, except for fecal coliform bacteria. During periods of high flow due to snowmelt or rainfall, concentrations of trace metal lead usually exceed recommended maximum levels. The primary sources of trace metal lead and suspended sediments are commercial areas , while the primary source of nutrients and fecal coliform bacteria is residential areas. Streamflow and water quality data collected at five sites representing different land-use categories were used to calibrate and verify three U.S. Geological Survey computer-based models: the Distributed Routing Rainfall-Runoff Model-Version II (DR3M-II), the Multi-Event Urban Runoff Quality Model (DR3M-QUAL), and the Precipitation Runoff Modeling Systems (PRMS). The PRMS can be used to simulate the effects of increased urbanization on daily flows. The DR3M-II can be used to simulate storm effects on small basins of < 40 acres. The DR3M-QUAL can be used to estimate seasonal loads of suspended sediment from basins of < 40 acres. (Lantz-PTT)

  8. Aluminium chloride promotes anchorage-independent growth in human mammary epithelial cells.

    Science.gov (United States)

    Sappino, André-Pascal; Buser, Raphaële; Lesne, Laurence; Gimelli, Stefania; Béna, Frédérique; Belin, Dominique; Mandriota, Stefano J

    2012-03-01

    Aluminium salts used as antiperspirants have been incriminated as contributing to breast cancer incidence in Western societies. To date, very little or no epidemiological or experimental data confirm or infirm this hypothesis. We report here that in MCF-10A human mammary epithelial cells, a well-established normal human mammary epithelial cell model, long-term exposure to aluminium chloride (AlCl(3) ) concentrations of 10-300 µ m, i.e. up to 100 000-fold lower than those found in antiperspirants, and in the range of those recently measured in the human breast, results in loss of contact inhibition and anchorage-independent growth. These effects were preceded by an increase of DNA synthesis, DNA double strand breaks (DSBs), and senescence in proliferating cultures. AlCl(3) also induced DSBs and senescence in proliferating primary human mammary epithelial cells. In contrast, it had no similar effects on human keratinocytes or fibroblasts, and was not detectably mutagenic in bacteria. MCF-10A cells morphologically transformed by long-term exposure to AlCl(3) display strong upregulation of the p53/p21(Waf1) pathway, a key mediator of growth arrest and senescence. These results suggest that aluminium is not generically mutagenic, but similar to an activated oncogene, it induces proliferation stress, DSBs and senescence in normal mammary epithelial cells; and that long-term exposure to AlCl(3) generates and selects for cells able to bypass p53/p21(Waf1) -mediated cellular senescence. Our observations do not formally identify aluminium as a breast carcinogen, but challenge the safety ascribed to its widespread use in underarm cosmetics. Copyright © 2012 John Wiley & Sons, Ltd.

  9. Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells

    International Nuclear Information System (INIS)

    Diaz-Valdivia, Natalia; Bravo, Denisse; Huerta, Hernán; Henriquez, Soledad; Gabler, Fernando; Vega, Margarita; Romero, Carmen; Calderon, Claudia; Owen, Gareth I.; Leyton, Lisette; Quest, Andrew F. G.

    2015-01-01

    Caveolin-1 (CAV1) has been implicated both in tumor suppression and progression, whereby the specific role appears to be context dependent. Endometrial cancer is one of the most common malignancies of the female genital tract; however, little is known about the role of CAV1 in this disease. Here, we first determined by immunohistochemistry CAV1 protein levels in normal proliferative human endometrium and endometrial tumor samples. Then using two endometrial cancer cell lines (ECC: Ishikawa and Hec-1A) we evaluated mRNA and protein levels of CAV1 by real time qPCR and Western blot analysis, respectively. The role of CAV1 expression in ECC malignancy was further studied by either inducing its expression in endometrial cancer cells with the tumor promotor 12-O-tetradecanoyl-phorbol-13-acetate (4β-TPA) or decreasing expression using short-hairpin RNA constructs, and then evaluating the effects of these changes on ECC proliferation, transmigration, matrigel invasion, and colony formation in soft agar. Immunohistochemical analysis of endometrial epithelia revealed that substantially higher levels of CAV1 were present in endometrial tumors than the normal proliferative epithelium. Also, in Ishikawa and Hec-1A endometrial cancer cells CAV1 expression was readily detectable. Upon treatment with 4β-TPA CAV1 levels increased and coincided with augmented cell transmigration, matrigel invasion, as well as colony formation in soft agar. Reduction of CAV1 expression using short-hairpin RNA constructs ablated these effects in both cell types whether treated or not with 4β-TPA. Alternatively, CAV1 expression appeared not to modulate significantly proliferation of these cells. Our study shows that elevated CAV1, observed in patients with endometrial cancer, is linked to enhanced malignancy of endometrial cancer cells, as evidenced by increased migration, invasion and anchorage-independent growth. The online version of this article (doi:10.1186/s12885-015-1477-5) contains

  10. Preliminary assessment report for Camp Carroll Training Center, Installation 02045, Anchorage, Alaska. Installation Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Krokosz, M.; Sefano, J.

    1993-08-01

    This report presents the results of the preliminary assessment (PA) conducted by Argonne National Laboratory at the Alaska Army National Guard property known as Camp Carroll Training Center, located on the Fort Richardson Army facility near Anchorage, Alaska. Preliminary assessments of federal facilities are being conducted to compile the information necessary for the completion of preremedial activities and to provide a basis for establishing, corrective actions in response to releases of hazardous substances. The principal objective of the PA is to characterize the site accurately and determine the need for further action by examining site activities, types and quantities of hazardous substances used, the nature and amounts of wastes generated or stored at the facility, and potential pathways by which contamination could affect public health and the environment. The primary environmentally significant operations (ESOs) associated with the property are (1) the Alaska Air National Guard storage area behind Building S57112 (Organizational Maintenance Shop [OMS] 6); (2) the state of Alaska maintenance facility and the soil/tar-type spill north of the state of Alaska maintenance facility; (3) the waste storage area adjacent to OMS 6; (4) the contaminated area from leaking underground storage tanks (USTs) and the oil-water separator; and (5) soil staining in the parking area at the Camp Carroll Headquarters Building. Camp Carroll appears to be in excellent condition from an environmental standpoint, and current practices are satisfactory. Argonne recommends that the Alaska Department of Military Affairs consider remediation of soil contamination associated with all storage areas, as well as reviewing the practices of other residents of the facility. Argonne also recommends that the current methods of storing waste material behind Building S57112 (OMS 6) be reviewed for alternatives.

  11. Mini-placa como ancoragem ortodôntica: relato de caso Mini screw as orthodontic anchorage: case report

    Directory of Open Access Journals (Sweden)

    André Luiz Zétola

    2005-08-01

    ígida pode ser utilizada com bastante propriedade no tratamento ortodôntico qunado for requerida uma ancoragem máxima.It is needless to say that anchorage control is necessary to a successful orthodontic treatment. Without it, it would be impossible to obtain an ideal occlusion through orthodontic mechanics in the majority of cases. The utilization of rigid devices, originated from face traumatology and implant dentistry principles, to obtain rigid anchorage in orthodontics revolutionized the way of treating cases with an unsatisfactory prognosis. Specially in cases where a lot of anchorage is needed and it is difficult or impossible to get it. The objective of this article was to revise the literature related to the use of mini-screw implant systems, to report a case where it was utilized and to discuss some aspects related to the usage of rigid anchorage orthodontics. The rigid anchorage was used in a 39 year old female patient, who had the upper left molars with a relevant extrusion due to the absence of the lower left molars. Fixed appliances were placed on the upper arch with a TPA connecting the second bicuspids. The TPA was used to anchor the intrusion of the upper left molars. A quad-helix appliance was used to correct the upper right third molar crossbite. Since the orthodontic intrusion with only dental anchorage did not have a satisfactory result, an "L" shaped titanium plate was placed on the maxilla, at the apical region of the upper first and second left molars, with the purpose of obtaining a rigid orthodontic anchorage to intrude them. Elastics were used during five months with intrusive force,the obtained intrusion was 6 millimeters. After the removal of the appliance, upper and lower dental bleaching was made and final prosthesis were placed over the implants. Through the literature reviewed and the case reported, it can be concluded that rigid anchorage can be indicated in orthodontic treatments where there is lack of anchorage or the need of an absolute

  12. Comparison of rate of En masse retraction and anchorage loss in conventional labial appliance with labial and lingual force: A clinical study

    Directory of Open Access Journals (Sweden)

    Dilshad Quraishi

    2018-01-01

    Full Text Available Aims: The rate of en masse retraction and anchorage loss were compared between labial appliance with lingual force and conventional labial appliance. Subjects and Methods: The sample consists of 14 patients and they were divided into two groups. In Group 1 – labial appliance with lingual force, elastomeric chain was placed from the palatal surface of the canines to the palatal surface of the molars. In Group 2 – labial appliance with labial force, elastomeric chain was placed from the crimpable hook distal to lateral incisor to the molar tube hooks. The rate of en masse retraction and anchorage loss was calculated for both the groups during retraction in dental casts (R0, initial; R1, 4 weeks; R2, 8 weeks; and R3, 12 weeks. Statistical Analysis Used: Student's paired t-test. Results: The rate of retraction was faster and anchorage loss was lower with labial appliance with lingual force, i.e., Group 1. The difference of anchorage loss in Group 1 and Group 2 shows t = 4.824 and P value= 0.000, which is statistically highly significant. The difference of rate of retraction in Group 1 and Group 2 shows t = 3.573 and P value = 0.004, which is statistically signifcant. Conclusions: The rate of retraction was faster and anchorage loss was lower with labial appliance with lingual force, thus indicating that this new technique of space closure utilizes biomechanical advantage of lingual force in conventional labial appliance.

  13. Mini-screw implant or transpalatal arch-mediated anchorage reinforcement during canine retraction: a randomized clinical trial.

    Science.gov (United States)

    Sharma, Mohit; Sharma, Vineet; Khanna, Bharat

    2012-06-01

    To compare mesial movement of upper first molars during maxillary canine retraction using a pre-adjusted edgewise appliance provided by anchorage reinforcement and a transpalatal arch or mini-screw implant. Randomized clinical trial. Department of Orthodontics and Dentofacial Orthopedics, Armed Forces Medical College, Pune, India. From a cohort of subjects requiring the extraction of both upper first premolars and pre-adjusted edgewise appliances to correct their malocclusion, a total of 30 were randomly allocated to receive two different forms of anchorage reinforcement: group A--receiving mini-screw implant and group B--receiving a transpalatal arch Group A subjects received titanium mini-screw implants placed at the start of treatment between the maxillary second premolar and maxillary first molar. Maxillary second premolars were secured to the mini-screw implants using of 0.010-inch stainless steel ligature wire. Group B subjects received a custom-made transpalatal arch which was soldered to maxillary first molar bands. Active canine retraction was initiated in both groups on placement of a 0.019×0.025-inch stainless steel archwire using nickel titanium closed coil springs. Mesial movement of the upper first molars as measured on pre- (T1) and post-treatment (T2) lateral skull radiographs. The results showed that in group A the mean mesial movement of the first molars between T1 and T2 was 0.0 mm (SD 0.02; P = 0.90), whereas in Group B there was a mean forward movement of the first maolars of 2.48 mm (SD 0.71; Pimplants placed prior to levelling and aligning were able to provide absolute anchorage during maxillary canine retraction, in contrast to a transpalatal arch.

  14. Induced ankylosis of a primary molar for skeletal anchorage in the mandible as alternative to mini-implants.

    Science.gov (United States)

    Angelopoulou, Matina V; Koletsi, Despina; Vadiakas, George; Halazonetis, Demetrios J

    2015-01-01

    Mesial protraction of mandibular posterior teeth requires increased anchorage to avoid undesired tooth movements. Orthodontic mini-implants have become a popular and successful way to increase skeletal anchorage in such cases. However, mini-implants may cause injury to adjacent teeth or anatomical structures and may lead to tissue inflammation. Induced ankylosed primary teeth have been used in the past as abutments for the protraction of the maxilla in cases of maxillary retrognathism. However, this technique has not been described in the literature for the protraction of mandibular molars. The aim of this paper is to present, through a case report, an alternative to mini-implant devices to maximize anchorage in the mandible by inducing ankylosis on a primary molar. A 13-year-old female with class II right malocclusion, deep bite, and congenitally missing right second premolars was referred for orthodontic treatment. Treatment plan involved removal of the primary teeth and mesial protraction of the posterior. In the mandible, ankylosis was induced on the retained primary second molar by extraction, bisection, replantation of the mesial part after endodontic treatment, and bonding of a rigid splint. Ankylosis was diagnosed after 10 weeks and a closing T-loop sectional wire was inserted to move the permanent first molar mesially. At 6 months, the remaining space was closed using elastic chain on a rectangular stainless steel wire with tip-back bends, supported by class II elastics. Induced ankylosis of primary teeth can be an alternative to orthodontic mini-implants in selected cases, with minimal risks and maximum biocompatibility.

  15. Combining oxygen plasma treatment with anchorage of cationized gelatin for enhancing cell affinity of poly(lactide-co-glycolide).

    Science.gov (United States)

    Shen, Hong; Hu, Xixue; Yang, Fei; Bei, Jianzhong; Wang, Shenguo

    2007-10-01

    Surface characteristics greatly influence attachment and growth of cells on biomaterials. Although polylactone-type biodegradable polymers have been widely used as scaffold materials for tissue engineering, lack of cell recognition sites, poor hydrophilicity and low surface energy lead to a bad cell affinity of the polymers, which limit the usage of polymers as scaffolds in tissue engineering. In the present study, surface of poly (L-lactide-co-glycolide) (PLGA) was modified by a method of combining oxygen plasma treatment with anchorage of cationized gelatin. Modification effect of the method was compared with other methods of oxygen plasma treatment, cationized gelatin or gelatin coating and combining oxygen plasma treatment with anchorage of gelatin. The change of surface property was compared by contact angles, surface energy, X-ray photoelectron spectra (XPS), attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM) measurement. The optimum oxygen pretreatment time determined by surface energy was 10 min when the power was 50 W and the oxygen pressure was 20 Pa. Analysis of the stability of gelatin and cationized gelatin anchored on PLGA by XPS, ATR-FTIR, contact angles and surface energy measurement indicated the cationized gelatin was more stable than gelatin. The result using mouse NIH 3T3 fibroblasts as model cells to evaluate cell affinity in vitro showed the cationized gelatin-anchored PLGA (OCG-PLGA) was more favorable for cell attachment and growth than oxygen plasma treated PLGA (O-PLGA) and gelatin-anchored PLGA (OG-PLGA). Moreover cell affinity of OCG-PLGA could match that of collagen-anchored PLGA (AC-PLGA). So the surface modification method combining oxygen plasma treatment with anchorage of cationized gelatin provides a universally effective way to enhance cell affinity of polylactone-type biodegradable polymers.

  16. Intrusão dentária utilizando mini-implantes Orthodontic intrusion with mini-implant anchorage

    Directory of Open Access Journals (Sweden)

    Telma Martins de Araújo

    2008-10-01

    Full Text Available INTRODUÇÃO: dentre os diversos tipos de movimentos dentários induzidos ortodonticamente, o de intrusão é, sem dúvida, um dos mais difíceis de serem conseguidos. A mecânica intrusiva convencional, apesar de viável, é complexa, no que diz respeito ao controle de seus efeitos colaterais. Isso, em grande parte, refere-se à dificuldade em se obter uma ancoragem satisfatória. Neste contexto, os mini-implantes, por oferecerem efetiva ancoragem esquelética, têm se mostrado de extrema valia para os ortodontistas, tornando a intrusão, tanto de dentes anteriores quanto posteriores, um procedimento cada vez mais simples, do ponto de vista mecânico. OBJETIVO: pretende-se, então, neste artigo, descrever e demonstrar, clinicamente, as diversas possibilidades de utilização dos mini-implantes como recurso de ancoragem para o movimento de intrusão.INTRODUCTION: Among all different varieties of orthodontically induced tooth movement, intrusion is, without doubt, one of the most difficult movements to be reached. Conventional intrusive biomechanics, although possible, may lead to undesirable side-effects. These events, in most cases, are related to the difficulty in obtaining an efficient anchorage unit. Then, mini-implants, because of their high success rates of effective skeletal anchorage, are valuable devices to orthodontists, transforming the intrusion movement, both at the anterior and the posterior regions, a more and more uncomplicated biomechanical procedure. AIM: to describe and show, clinically, different ways of using mini-implants as an anchorage system to intrusion movement.

  17. Response of a 14-story Anchorage, Alaska, building in 2002 to two close earthquakes and two distant Denali fault earthquakes

    Science.gov (United States)

    Celebi, M.

    2004-01-01

    The recorded responses of an Anchorage, Alaska, building during four significant earthquakes that occurred in 2002 are studied. Two earthquakes, including the 3 November 2002 M7.9 Denali fault earthquake, with epicenters approximately 275 km from the building, generated long trains of long-period (>1 s) surface waves. The other two smaller earthquakes occurred at subcrustal depths practically beneath Anchorage and produced higher frequency motions. These two pairs of earthquakes have different impacts on the response of the building. Higher modes are more pronounced in the building response during the smaller nearby events. The building responses indicate that the close-coupling of translational and torsional modes causes a significant beating effect. It is also possible that there is some resonance occurring due to the site frequency being close to the structural frequency. Identification of dynamic characteristics and behavior of buildings can provide important lessons for future earthquake-resistant designs and retrofit of existing buildings. ?? 2004, Earthquake Engineering Research Institute.

  18. Asymmetrical distalization of maxillary molars with zygomatic anchorage, improved superelastic nickel-titanium alloy wires, and open-coil springs.

    Science.gov (United States)

    Ishida, Takayoshi; Yoon, Hyung Sik; Ono, Takashi

    2013-10-01

    In nongrowing patients with skeletal Class II malocclusion, premolar extraction or maxillary distalization can be used as camouflage treatment. Zygomatic anchorage enables distalization in uncooperative or noncompliant patients. We describe 1 such procedure in a 24-year-old woman. We used novel improved superelastic nickel-titanium archwires combined with nickel-titanium open-coil springs to provide a constant and continuous low force to the dentition. We were able to successfully eliminate the protrusive profile and correct the Class II molar relationship using this system of zygomatic anchorage. The posterior occlusal relationships were improved to achieve Class I canine and molar relationships on both sides, and ideal overbite and overjet relationships were established. Facial esthetics was improved with decreased protrusion of the upper and lower lips. The method used here is a promising alternative to traditional distalization techniques and might offer an effective and simple means of distalizing maxillary molars in uncooperative patients. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  19. Comparison of tooth displacement between buccal mini-implants and palatal plate anchorage for molar distalization: a finite element study.

    Science.gov (United States)

    Yu, Il-Jun; Kook, Yoon-Ah; Sung, Sang-Jin; Lee, Kee-Joon; Chun, Youn-Sic; Mo, Sung-Seo

    2014-08-01

    The purposes of this study were to mechanically evaluate distalization modalities through the application of skeletal anchorage using finite element analysis. Base models were constructed from commercial teeth models. A finite element model was created and three treatment modalities were modified to make 10 models. Modalities 1 and 2 placed mini-implants in the buccal side, and modality 3 placed a plate on the palatal side. Distalization with the palatal plate in modality 3 showed bodily molar movement and insignificant displacement of the incisors. Placing mini-implants on the buccal side in modalities 1 and 2 caused the first molar to be distally tipped and extruded, while the incisors were labially flared and intruded. Distalization with the palatal plate rather than mini-implants on the buccal side provided bodily molar movement without tipping or extrusion. It is recommended to use our findings as a clinical guide for the application of skeletal anchorage devices for molar distalization. © The Author 2011. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  20. Morphologic and hemodynamic analysis of dental pulp in dogs after molar intrusion with the skeletal anchorage system.

    Science.gov (United States)

    Konno, Yuichi; Daimaruya, Takayoshi; Iikubo, Masahiro; Kanzaki, Reiko; Takahashi, Ichiro; Sugawara, Junji; Sasano, Takashi

    2007-08-01

    We have successfully treated skeletal open bite by intruding posterior teeth with the skeletal anchorage system. Our aim in this study was to morphologically and hemodynamically evaluate the changes in pulp tissues when molars are radically intruded. The mandibular fourth premolars of 9 adult beagle dogs were divided into 3 groups: a sham operated group (n = 6, 3 dogs), 4-month intrusion group (n = 6, 3 dogs), and a further 4-month retention group (n = 6, 3 dogs). We evaluated the morphological changes of the pulp and dentin-the amount of vacuolar degeneration in the odontoblast layer, the predentin width and nervous continuity in the pulp tissue, and the pulpal blood-flow response evoked by electrical stimulation in the dental pulp. Extreme molar intrusion with the skeletal anchorage system caused slight degenerative changes in the pulp tissue, followed by recovery after the orthodontic force was released. Circulatory system and nervous functions were basically maintained during the intrusion, although a certain level of downregulation was observed. These morphologic and functional regressive changes in the pulp tissue after molar intrusion improved during the retention period. Histologic changes and changes in pulpal blood flow and function are reversible, even during radical intrusion of molars.

  1. Intrusion of maxillary incisors by mini-screw anchorage of Angle Class II division 2 malocclusion cases.

    Science.gov (United States)

    Al-Falahi, Bilal A; Hammad, Shaza M; El-Kenawy, Mohammed H; Fouda, Maher A

    2012-01-01

    to evaluate the effects of the upper incisor teeth intrusion by mini-screw on the amount of overbite and on the dental and skeletal parameters of the jaws. Ten patients were selected from the outpatient clinic of the Department of Orthodontics, Faculty of Dentistry, Mansoura University with Angle's Class II division 2 malocclusions. Ages ranged from 13 to 19 years with deep overbite of 4mm or more requiring intrusion of the maxillary incisors. Alignment of the upper and lower dental arches was done with a pre-adjusted edgewise technique, then a mini-screw as anchorage for the intrusion of the upper incisor segment was inserted for every patient below the anterior nasal spine connected to a utility arch wire. The overbite was corrected from 6 mm to 1.8 mm (p<.001) by upper incisor intrusion and the gummy smile was improved. No extrusion of upper first permanent molars was observed. The maxillary incisors were effectively intruded by using mini-screws as orthodontic anchorage. Good occlusion and facial esthetics were achieved with no counteractive movements in the molars.

  2. Barium promotes anchorage-independent growth and invasion of human HaCaT keratinocytes via activation of c-SRC kinase.

    Science.gov (United States)

    Thang, Nguyen Dinh; Yajima, Ichiro; Kumasaka, Mayuko Y; Ohnuma, Shoko; Yanagishita, Takeshi; Hayashi, Rumiko; Shekhar, Hossain U; Watanabe, Daisuke; Kato, Masashi

    2011-01-01

    Explosive increases in skin cancers have been reported in more than 36 million patients with arsenicosis caused by drinking arsenic-polluted well water. This study and previous studies showed high levels of barium as well as arsenic in the well water. However, there have been no reports showing a correlation between barium and cancer. In this study, we examined whether barium (BaCl(2)) may independently have cancer-related effects on human precancerous keratinocytes (HaCaT). Barium (5-50 µM) biologically promoted anchorage-independent growth and invasion of HaCaT cells in vitro. Barium (5 µM) biochemically enhanced activities of c-SRC, FAK, ERK and MT1-MMP molecules, which regulate anchorage-independent growth and/or invasion. A SRC kinase specific inhibitor, protein phosphatase 2 (PP2), blocked barium-mediated promotion of anchorage-independent growth and invasion with decreased c-SRC kinase activity. Barium (2.5-5 µM) also promoted anchorage-independent growth and invasion of fibroblasts (NIH3T3) and immortalized nontumorigenic melanocytes (melan-a), but not transformed cutaneous squamous cell carcinoma (HSC5 and A431) and malignant melanoma (Mel-ret) cells, with activation of c-SRC kinase. Taken together, our biological and biochemical findings newly suggest that the levels of barium shown in drinking well water independently has the cancer-promoting effects on precancerous keratinocytes, fibroblast and melanocytes in vitro.

  3. Remains of the ancient ports and anchorage points at Miyani and Visawada, on the west coast of India: A study based on underwater investigations

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh; Tripati, S.

    as an excellent natural harbour. The important antiquities include varieties of stone anchors, which are very similar to those reported from Dwarka and Bet Dwarka. The identification of ancient anchorage points between water depth of 5 and 15 m is another...

  4. Anchorage of TiO2-blasted, HA-coated, and machined implants: an experimental study with rabbits

    DEFF Research Database (Denmark)

    Gotfredsen, K; Wennerberg, A; Johansson, C

    1995-01-01

    The purpose of this study was to evaluate the histometrical and biomechanical anchorage of TiO2-blasted implants and TiO2-blasted implants coated with hydroxyapatite. The control implants were machined. Twenty-six rabbits had a total of 156 implants placed in the proximal part of the tibia. Each...... rabbit had a machined, a TiO2-blasted, and a TiO2-blasted, HA-coated implant placed in each tibia. After a healing period of 3 and 12 weeks, respectively, the implants placed in the right tibia were used for removal torque test, and the implants placed in the left tibia were used for histomorphometrical...... measurements. Preoperatively, implants from the same batches were examined topographically with a TopScan 3D system. The TiO2-blasted implants demonstrated significantly higher removal torque values than the machined implants, and they also had a significantly more irregular surface. Furthermore, significantly...

  5. Characterization of the aspects of osteoprogenitor cell interactions with physical tetracalcium phosphate anchorage on titanium implant surfaces

    International Nuclear Information System (INIS)

    Ko, Chia-Ling; Chang, Ya-Yuan; Liou, Cian-Hua; Chen, Wen-Cheng

    2015-01-01

    Well-designed implants are used not only to modify the geometry of the implant but also to change the chemical properties of its surfaces. The present study aims to assess the biofunctional effects of tetracalcium phosphate (TTCP) particles as a physical anchor on the implant surface derived through sandblasting. The characteristics of the surface, cell viability, and alkaline phosphatase (ALP) activity toward osteoprogenitor cells (D1) were obtained. D1 cells were cultured on a plain surface that underwent sandblasting and acid etching (SLA) (control SLA group) and on different SLA surfaces with different anchoring TTCP rates (new test groups, M and H). The mean anchoring rates were 57% (M) and 74% (H), and the anchored thickness was estimated to range from 12.6 μm to 18.3 μm. Compared with the control SLA surface on Ti substrate, the new test groups with different TTCP anchoring rates (M and H) failed to improve cell proliferation significantly but had a well-differentiated D1 cell phenotype that enhanced ALP expression in the early stage of cell cultures, specifically, at day 7. Results suggest that the SLA surface with anchored TTCP can accelerate progenitor bone cell mineralization. This study shows the potential clinical application of the constructed geometry in TTCP anchorage on Ti for dental implant surface modification. - Highlights: • TTCP (tetracalcium phosphate) as a physical anchorage on implant is characterized. • Theoretical values of anchored thickness and capping areas were estimated. • TTCP anchored by sandblasting can accelerate progenitor bone cell mineralization. • TTCP anchored on SLA (sandblasting and acid etching) surface is a promising method

  6. Effect of molar intrusion with temporary anchorage devices in patients with anterior open bite: a systematic review.

    Science.gov (United States)

    Alsafadi, Ahmad Saleem; Alabdullah, Mohannad M; Saltaji, Humam; Abdo, Anas; Youssef, Mohamed

    2016-01-01

    The objective of the study is to assess the effect of molar intrusion with temporary anchorage devices on the vertical facial morphology and mandibular rotation during open bite treatment in the permanent dentition. We performed a systematic review of the published data in seven electronic databases up to September 2015. We considered studies for inclusion if they were examining the effects of posterior teeth intrusion on the vertical facial morphology with open bite malocclusion in the permanent dentition. Study selection, risk of bias assessment, and data-extraction were performed in duplicate. Meta-analysis was not possible due to dissimilarity and heterogeneity among the included studies. Out of the 42 articles that met the initial eligibility criteria, 12 studies were finally selected. Low level of scientific evidence was identified after risk of bias assessment of the included studies with no relevant randomized controlled trial performed. Out of the 12 selected studies, five studies used miniplates and seven studies used miniscrews. Mandibular counterclockwise rotation was found to be between 2.3° and 3.9° in six studies (as sassed by mandibular plane angle, between MeGo or GoGn and SN or FH plane) while it was less than 2° in the remaining studies. Current weak evidence suggests that molar intrusion with temporary anchorage devices may cause mandibular counterclockwise autorotation. Future well-conducted and clearly reported multicenter randomized controlled trials that include a non-treatment control group are needed to make robust recommendations regarding the amount of mandibular rotation during open bite treatments.

  7. Effect of molar intrusion with temporary anchorage devices in patients with anterior open bite: a systematic review

    Directory of Open Access Journals (Sweden)

    Ahmad Saleem Alsafadi

    2016-03-01

    Full Text Available Abstract Objective The objective of the study is to assess the effect of molar intrusion with temporary anchorage devices on the vertical facial morphology and mandibular rotation during open bite treatment in the permanent dentition. Methods We performed a systematic review of the published data in seven electronic databases up to September 2015. We considered studies for inclusion if they were examining the effects of posterior teeth intrusion on the vertical facial morphology with open bite malocclusion in the permanent dentition. Study selection, risk of bias assessment, and data-extraction were performed in duplicate. Meta-analysis was not possible due to dissimilarity and heterogeneity among the included studies. Results Out of the 42 articles that met the initial eligibility criteria, 12 studies were finally selected. Low level of scientific evidence was identified after risk of bias assessment of the included studies with no relevant randomized controlled trial performed. Out of the 12 selected studies, five studies used miniplates and seven studies used miniscrews. Mandibular counterclockwise rotation was found to be between 2.3° and 3.9° in six studies (as sassed by mandibular plane angle, between MeGo or GoGn and SN or FH plane while it was less than 2° in the remaining studies. Conclusions Current weak evidence suggests that molar intrusion with temporary anchorage devices may cause mandibular counterclockwise autorotation. Future well-conducted and clearly reported multicenter randomized controlled trials that include a non-treatment control group are needed to make robust recommendations regarding the amount of mandibular rotation during open bite treatments.

  8. Characterization of the aspects of osteoprogenitor cell interactions with physical tetracalcium phosphate anchorage on titanium implant surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Chia-Ling [Advanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan (China); Dental Medical Devices and Materials Research Center, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan (China); Chang, Ya-Yuan; Liou, Cian-Hua [Alliance Global Technology Co., Ltd., Kaohsiung Medical Device Special Zone in Southern Taiwan Science Park, Kaohsiung 82151, Taiwan (China); Chen, Wen-Cheng, E-mail: wencchen@fcu.edu.tw [Advanced Medical Devices and Composites Laboratory, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan (China)

    2015-04-01

    Well-designed implants are used not only to modify the geometry of the implant but also to change the chemical properties of its surfaces. The present study aims to assess the biofunctional effects of tetracalcium phosphate (TTCP) particles as a physical anchor on the implant surface derived through sandblasting. The characteristics of the surface, cell viability, and alkaline phosphatase (ALP) activity toward osteoprogenitor cells (D1) were obtained. D1 cells were cultured on a plain surface that underwent sandblasting and acid etching (SLA) (control SLA group) and on different SLA surfaces with different anchoring TTCP rates (new test groups, M and H). The mean anchoring rates were 57% (M) and 74% (H), and the anchored thickness was estimated to range from 12.6 μm to 18.3 μm. Compared with the control SLA surface on Ti substrate, the new test groups with different TTCP anchoring rates (M and H) failed to improve cell proliferation significantly but had a well-differentiated D1 cell phenotype that enhanced ALP expression in the early stage of cell cultures, specifically, at day 7. Results suggest that the SLA surface with anchored TTCP can accelerate progenitor bone cell mineralization. This study shows the potential clinical application of the constructed geometry in TTCP anchorage on Ti for dental implant surface modification. - Highlights: • TTCP (tetracalcium phosphate) as a physical anchorage on implant is characterized. • Theoretical values of anchored thickness and capping areas were estimated. • TTCP anchored by sandblasting can accelerate progenitor bone cell mineralization. • TTCP anchored on SLA (sandblasting and acid etching) surface is a promising method.

  9. Nonextraction treatment with temporary skeletal anchorage devices to correct a Class II Division 2 malocclusion with excessive gingival display.

    Science.gov (United States)

    Nishimura, Makoto; Sannohe, Minayo; Nagasaka, Hiroshi; Igarashi, Kaoru; Sugawara, Junji

    2014-01-01

    The patient was a 22-year-old Japanese woman who complained of a gummy smile. She had several other orthodontic problems, including crowding of the maxillary anterior teeth, retroclination of the maxillary central incisors, excessive maxillary incisor display, a deep overbite, Class II dental relationships, a Class II profile, and a long face. Two options for the correction of these problems were proposed. The first option was to extract the maxillary first premolars to correct the Class II relationship and implant a miniscrew to correct the gingival display; the second option was to place 2 miniplates for distalization of the maxillary molars and a miniscrew to correct the gingival smile without premolar extractions. The patient chose the second option. After placing a preadjusted bracketed system, 2 miniplates were placed in the zygomatic buttresses bilaterally with monocortical screws, and 1 miniscrew was fixed between the root apices of the maxillary central incisors. Distalization and intrusion of the maxillary molars and intrusion of the maxillary incisors were simultaneously started with those temporary skeletal anchorage devices functioning as absolute orthodontic anchors. The total treatment period was approximately 22 months. Her orthodontic problems were corrected. According to the cephalometric evaluation, the entire maxillary dentition was significantly distalized, and her maxillary incisors were successfully intruded, with the mandible showing a slight counterclockwise rotation. Thanks to the temporary anchorage devices combined with miniplates and a miniscrew, we were able to predictably achieve her treatment goals without premolar extractions, orthognathic surgery, and the need for patient compliance. Copyright © 2014 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  10. Outbreak of Invasive Infections From Subtype emm26.3 Group A Streptococcus Among Homeless Adults-Anchorage, Alaska, 2016-2017.

    Science.gov (United States)

    Mosites, Emily; Frick, Anna; Gounder, Prabhu; Castrodale, Louisa; Li, Yuan; Rudolph, Karen; Hurlburt, Debby; Lecy, Kristen D; Zulz, Tammy; Adebanjo, Tolu; Onukwube, Jennifer; Beall, Bernard; Van Beneden, Chris A; Hennessy, Thomas; McLaughlin, Joseph; Bruce, Michael G

    2018-03-19

    In 2016, we detected an outbreak of group A Streptococcus (GAS) invasive infections among the estimated 1000 persons experiencing homelessness (PEH) in Anchorage, Alaska. We characterized the outbreak and implemented a mass antibiotic intervention at homeless service facilities. We identified cases through the Alaska GAS laboratory-based surveillance system. We conducted emm typing, antimicrobial susceptibility testing, and whole-genome sequencing on all invasive isolates and compared medical record data of patients infected with emm26.3 and other emm types. In February 2017, we offered PEH at 6 facilities in Anchorage a single dose of 1 g of azithromycin. We collected oropharyngeal and nonintact skin swabs on a subset of participants concurrent with the intervention and 4 weeks afterward. From July 2016 through April 2017, we detected 42 invasive emm26.3 cases in Anchorage, 35 of which were in PEH. The emm26.3 isolates differed on average by only 2 single-nucleotide polymorphisms. Compared to other emm types, infection with emm26.3 was associated with cellulitis (odds ratio [OR], 2.5; P = .04) and necrotizing fasciitis (OR, 4.4; P = .02). We dispensed antibiotics to 391 PEH. Colonization with emm26.3 decreased from 4% of 277 at baseline to 1% of 287 at follow-up (P = .05). Invasive GAS incidence decreased from 1.5 cases per 1000 PEH/week in the 6 weeks prior to the intervention to 0.2 cases per 1000 PEH/week in the 6 weeks after (P = .01). In an invasive GAS outbreak in PEH in Anchorage, mass antibiotic administration was temporally associated with reduced invasive disease cases and colonization prevalence.

  11. Assessing the Frequency and Material Consequences of Collisions with Vessels Lying at an Anchorage in Line with IALA iWrap MkII

    Directory of Open Access Journals (Sweden)

    Hans-Christoph Burmeister

    2014-03-01

    Full Text Available This paper proposes a collision model for ships underway and temporary objects as an extension to state-of-the-art maritime risk assessment like IALA iWrap MkII. It gives a brief review of frequency modeling's and consequence calculation theory as well as its applications, before it analogously derives a model to assess the risk of anchorage areas. Subsequently, its benefit is demonstrated by an example scenario.

  12. Changes in strain patterns after implantation of a short stem with metaphyseal anchorage compared to a standard stem: an experimental study in synthetic bone

    Directory of Open Access Journals (Sweden)

    Jens Gronewold

    2014-03-01

    Full Text Available Short stem hip arthroplasties with predominantly metaphyseal fixation, such as the METHA® stem (Aesculap, Tuttlingen, Germany, are recommended because they are presumed to allow a more physiologic load transfer and thus a reduction of stress-shielding. However, the hypothesized metaphyseal anchorage associated with the aforementioned benefits still needs to be verified. Therefore, the METHA short stem and the Bicontact® standard stem (Aesculap, Tuttlingen, Germany were tested biomechanically in synthetic femora while strain gauges monitored their corresponding strain patterns. For the METHA stem, the strains in all tested locations including the region of the calcar (87% of the non-implanted femur were similar to conditions of synthetic bone without implanted stem. The Bicontact stem showed approximately the level of strain of the non-implanted femur on the lateral and medial aspect in the proximal diaphysis of the femur. On the anterior and posterior aspect of the proximal metaphysis the strains reached averages of 78% and 87% of the non-implanted femur, respectively. This study revealed primary metaphyseal anchorage of the METHA short stem, as opposed to a metaphyseal-diaphyseal anchorage of the Bicontact stem.

  13. Nonsurgical treatment of an adult with a skeletal Class II gummy smile using zygomatic temporary anchorage devices and improved superelastic nickel-titanium alloy wires.

    Science.gov (United States)

    Ishida, Yuji; Ono, Takashi

    2017-11-01

    Patients with a severe gummy smile and a skeletal Class II profile are difficult to treat. This case report describes an effective treatment alternative for improving a gummy smile in a patient with a severe Class II molar relationship, severe crowding, and lip protrusion using zygomatic anchorage devices and improved superelastic nickel-titanium wires. A 36-year-old woman had an excessive overjet and a deep overbite with a bilateral Angle Class II molar relationship. The cephalometric analysis demonstrated a Class II skeletal relationship (ANB, 9.5°), retroclination of the mandible (FMA, 38.4°), and severe labial inclination of the mandibular incisors (IMPA, 101.9°). The main treatment objectives included normalizing the overjet and overbite, improving the gummy smile, and establishing a satisfactory occlusion. During treatment with fixed appliances, intrusion of the total maxillary dentition using skeletal anchorage and elimination of the bimaxillary protrusion were achieved. Improvement of the lateral profile and gummy smile enhanced facial esthetics. Intrusion and distalization of the maxillary dentition with skeletal anchorage and improved superelastic nickel-titanium wires provided a satisfactory dental occlusion, esthetic improvement, and adequate function. This approach should be considered as an alternative treatment option to orthognathic surgery for adults with high-angle skeletal Class II malocclusion and a gummy smile. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  14. Chlamydia induces anchorage independence in 3T3 cells and detrimental cytological defects in an infection model.

    Directory of Open Access Journals (Sweden)

    Andrea E Knowlton

    Full Text Available Chlamydia are gram negative, obligate intracellular bacterial organisms with different species causing a multitude of infections in both humans and animals. Chlamydia trachomatis is the causative agent of the sexually transmitted infection (STI Chlamydia, the most commonly acquired bacterial STI in the United States. Chlamydial infections have also been epidemiologically linked to cervical cancer in women co-infected with the human papillomavirus (HPV. We have previously shown chlamydial infection results in centrosome amplification and multipolar spindle formation leading to chromosomal instability. Many studies indicate that centrosome abnormalities, spindle defects, and chromosome segregation errors can lead to cell transformation. We hypothesize that the presence of these defects within infected dividing cells identifies a possible mechanism for Chlamydia as a cofactor in cervical cancer formation. Here we demonstrate that infection with Chlamydia trachomatis is able to transform 3T3 cells in soft agar resulting in anchorage independence and increased colony formation. Additionally, we show for the first time Chlamydia infects actively replicating cells in vivo. Infection of mice with Chlamydia results in significantly increased cell proliferation within the cervix, and in evidence of cervical dysplasia. Confocal examination of these infected tissues also revealed elements of chlamydial induced chromosome instability. These results contribute to a growing body of data implicating a role for Chlamydia in cervical cancer development and suggest a possible molecular mechanism for this effect.

  15. Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres

    Science.gov (United States)

    Czyz, Malgorzata; Koprowska, Kamila; Sztiller-Sikorska, Malgorzata

    2013-01-01

    Growing evidence suggests that the cancer stem cell phenotype in melanoma is dynamically regulated. Therefore, effective therapies have to target simultaneously bulk tumor cells and melanoma stem-like cells. The aim of the present study was to investigate the effects of parthenolide on heterogeneous cancer cell populations from anchorage-independent melanospheres. Cells derived from nodular melanoma specimens were grown under serum-free sphere-forming conditions. The effects of parthenolide on cellular viability, immunophenotype and self-renewing capacity were assessed with cells from dissociated melanospheres. Its penetration capacity was evaluated with intact melanospheres. In melanoma cells that survived treatment with parthenolide, a different immunophenotype than that in untreated control was found. The frequency of cells expressing the ABCB5 transporter was markedly reduced. Most importantly, melanoma cells that survived parthenolide treatment lost their self-renewing capacity. Significantly lower influence of drug on cellular viability and frequency of ABCB5-positive cells was observed in intact melanospheres. The potential clinical significance of our findings is based on the ability of parthenolide to affect both bulk and melanoma stem-like cells with clonogenic capacity and high expression of the ABCB5 transporter. Its low penetration capacity, however, may limit its action to easily accessible melanoma cells, either circulating in the blood or those in the vicinity to blood vessels within the tumor. Because of limited penetration capacity of parthenolide, this drug should be further explored as a part of multimodal therapies rather than as a stand-alone therapeutic agent. PMID:23192276

  16. Indirect usage of miniscrew anchorage to intrude overerupted mandibular incisors in a Class II patient with a deep overbite.

    Science.gov (United States)

    Ishihara, Yoshihito; Kuroda, Shingo; Sugawara, Yasuyo; Balam, Tarek A; Takano-Yamamoto, Teruko; Yamashiro, Takashi

    2013-04-01

    Vertical dentoalveolar discrepancies are a common problem in orthodontic patients but are often difficult to treat with traditional mechanics. This case report illustrates the successful treatment of overerupted mandibular incisors via the indirect use of miniscrew anchorage. A woman (age, 22 years 9 months) had chief complaints of maxillary incisor protrusion and crooked teeth. An excessive curve of Spee caused by elongation of the mandibular incisors was also found. The patient was diagnosed with a severe Class II Division 1 malocclusion and a deep overbite. After extraction of the mandibular first premolars and the subsequent leveling phase, the elongated incisors were intruded with a novel method, which involved the combined use of sectional archwires and miniscrews placed in the premolar areas. After the procedure, the mandibular incisors had been intruded by 6.5 mm with no undesirable side effects. The total active treatment period was 42 months. The resultant occlusion and satisfactory facial profile were maintained after 30 months of retention. Our novel intrusion approach shows potential for correcting a deep overbite. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  17. [Indirect usage of miniscrew anchorage to intrude overerupted mandibular incisors in a Class II patient with a deep overbite].

    Science.gov (United States)

    Ishihara, Yoshihito; Kuroda, Shingo; Sugawara, Yasuyo; Balam, Tarek A; Takano-Yamamoto, Teruko; Yamashiro, Takashi

    2016-06-01

    Vertical dentoalveolar discrepancies are a common problem in orthodontic patients but are often difficult to treat with traditional mechanics. This case report illustrates the successful treatment of overerupted mandibular incisors via the indirect use of miniscrew anchorage. A woman (age, 22 years 9 months) had chief complaints of maxillary incisor protrusion and crooked teeth. An excessive curve of Spee caused by elongation of the mandibular incisors was also found. The patient was diagnosed with a severe Class II Division 1 malocclusion and a deep overbite. After extraction of the mandibular first premolars and the subsequent leveling phase, the elongated incisors were intruded with a novel method, which involved the combined use of sectional archwires and miniscrews placed in the premolar areas. After the procedure, the mandibular incisors had been intruded by 6.5 mm with no undesirable side effects. The total active treatment period was 42 months. The resultant occlusion and satisfactory facial profile were maintained after 30 months of retention. Our novel intrusion approach shows potential for correcting a deep overbite. © EDP Sciences, SFODF, 2016.

  18. Treatment effects of occipitomental anchorage appliance of maxillary protraction combined with chincup traction in children with Class III malocclusion.

    Science.gov (United States)

    Lin, Hsiang-Chien; Chang, Hong-Po; Chang, Hsin-Fu

    2007-05-01

    Little information related to the treatment effects of the occipitomental anchorage (OMA) appliance of maxillary (Mx) protraction combined with chincup traction is available. The aim of this study was to investigate the treatment effects of the OMA orthopedic appliance on patients with Class III malocclusion. Pretreatment and post-treatment cephalometric records of 20 consecutively treated patients with Class III malocclusions were evaluated and compared with a matched sample of untreated Class III control subjects. The OMA appliance is effective for correcting skeletal Class III malocclusion in growing children. The treatment effects of this orthopedic appliance were considered to be from both skeletal and dentoalveolar changes. The skeletal effects were mainly obtained by stimulating forward growth of the Mx complex with negligible rotation of the Mx plane and restraining forward advancement of the mandible (Mn) with backward and downward rotation of the Mn plane. The observed dentoalveolar effects were mostly due to the labial tipping movement of the Mx incisors. Our results suggest that the OMA orthopedic appliance can correct the mesial jaw relationship and negative incisal over jet. This appliance is effective for correcting skeletal Class III malocclusion with both midface deficiency and Mn prognathism in growing children.

  19. Flexural strength of mini-implants developed for Herbst appliance skeletal anchorage: a study in Minipigs br1 cadavers

    Directory of Open Access Journals (Sweden)

    Klaus Barretto Lopes

    2013-12-01

    Full Text Available OBJECTIVE: The present study was designed to verify if mini-implant prototypes (MIP developed for Herbst appliance anchorage are capable of withstanding orthopedic forces, and to determine whether the flexural strength of these MIP varies depending on the site of insertion (maxilla and mandible. METHODS: Thirteen MIP were inserted in three minipig cadavers (six in the maxilla and seven in the mandible. The specimens were prepared and submitted to mechanical testing. The mean and standard deviation were calculated for each region. A two-way Student's t test was used to compare the strength between the sites. A one-way Student's t test was performed to test the hypothesis. Orthopedic forces above 1.0 kgf were considered. RESULTS: The MIP supported flexural strength higher than 1.0 kgf (13.8 ± 2.3 Kg, in the posterior region of the maxilla and 20.5 ± 5.2 Kg in the anterior region of the mandible with a significantly lower flexural strength in the anterior region of the mandible (P < 0.05. CONCLUSION: The MIP are capable of withstanding orthopedic forces, and are more resistant in the anterior region of the mandible than in the posterior region of the maxilla in Minipigs br1 cadavers.

  20. A Component-Based Study of the Effect of Diameter on Bond and Anchorage Characteristics of Blind-Bolted Connections.

    Directory of Open Access Journals (Sweden)

    Muhammad Nasir Amin

    Full Text Available Structural hollow sections are gaining worldwide importance due to their structural and architectural advantages over open steel sections. The only obstacle to their use is their connection with other structural members. To overcome the obstacle of tightening the bolt from one side has given birth to the concept of blind bolts. Blind bolts, being the practical solution to the connection hindrance for the use of hollow and concrete filled hollow sections play a vital role. Flowdrill, the Huck High Strength Blind Bolt and the Lindapter Hollobolt are the well-known commercially available blind bolts. Although the development of blind bolts has largely resolved this issue, the use of structural hollow sections remains limited to shear resistance. Therefore, a new modified version of the blind bolt, known as the "Extended Hollo-Bolt" (EHB due to its enhanced capacity for bonding with concrete, can overcome the issue of low moment resistance capacity associated with blind-bolted connections. The load transfer mechanism of this recently developed blind bolt remains unclear, however. This study uses a parametric approach to characterising the EHB, using diameter as the variable parameter. Stiffness and load-carrying capacity were evaluated at two different bolt sizes. To investigate the load transfer mechanism, a component-based study of the bond and anchorage characteristics was performed by breaking down the EHB into its components. The results of the study provide insight into the load transfer mechanism of the blind bolt in question. The proposed component-based model was validated by a spring model, through which the stiffness of the EHB was compared to that of its components combined. The combined stiffness of the components was found to be roughly equivalent to that of the EHB as a whole, validating the use of this component-based approach.

  1. Laser-Modified Surface Enhances Osseointegration and Biomechanical Anchorage of Commercially Pure Titanium Implants for Bone-Anchored Hearing Systems

    Science.gov (United States)

    Omar, Omar; Simonsson, Hanna; Palmquist, Anders; Thomsen, Peter

    2016-01-01

    Osseointegrated implants inserted in the temporal bone are a vital component of bone-anchored hearing systems (BAHS). Despite low implant failure levels, early loading protocols and simplified procedures necessitate the application of implants which promote bone formation, bone bonding and biomechanical stability. Here, screw-shaped, commercially pure titanium implants were selectively laser ablated within the thread valley using an Nd:YAG laser to produce a microtopography with a superimposed nanotexture and a thickened surface oxide layer. State-of-the-art machined implants served as controls. After eight weeks’ implantation in rabbit tibiae, resonance frequency analysis (RFA) values increased from insertion to retrieval for both implant types, while removal torque (RTQ) measurements showed 153% higher biomechanical anchorage of the laser-modified implants. Comparably high bone area (BA) and bone-implant contact (BIC) were recorded for both implant types but with distinctly different failure patterns following biomechanical testing. Fracture lines appeared within the bone ~30–50 μm from the laser-modified surface, while separation occurred at the bone-implant interface for the machined surface. Strong correlations were found between RTQ and BIC and between RFA at retrieval and BA. In the endosteal threads, where all the bone had formed de novo, the extracellular matrix composition, the mineralised bone area and osteocyte densities were comparable for the two types of implant. Using resin cast etching, osteocyte canaliculi were observed directly approaching the laser-modified implant surface. Transmission electron microscopy showed canaliculi in close proximity to the laser-modified surface, in addition to a highly ordered arrangement of collagen fibrils aligned parallel to the implant surface contour. It is concluded that the physico-chemical surface properties of laser-modified surfaces (thicker oxide, micro- and nanoscale texture) promote bone bonding

  2. Efficacy of transpalatal arch as an anchorage reinforcing unit during orthodontic space closure: A three-dimensional finite element study

    Directory of Open Access Journals (Sweden)

    Vishal Shrishail Kudagi

    2017-01-01

    Full Text Available Background and Objectives: Connecting the contralateral upper molars by means of a transpalatal arch (TPA is thought to decrease the tendency of the molars to move mesially in response to orthodontic force (i.e., provide orthodontic anchorage. This study was hence conducted to investigate the effects of the TPA on the displacement of the molars and stresses generated in the periodontium during orthodontic tooth movement using the finite element method (FEM. Materials and Methods: A three-dimensional (3D model was generated using medical modeling software (Mimics using the computed tomography slice images of the skull which were obtained at a slice thickness of 1 mm. From this, the finite element model was built using HyperMesh and analysis was performed using PATRAN software (MSC Software Corporation, 4675 MacArthur Court, Newport Beach, California 92660. The 3D finite element models were fabricated in two versions such as maxillary first molars including their associated periodontal ligament and alveolar bone one with TPA and another without TPA. Both were subjected to orthodontic forces, and the resultant stress patterns and displacements between the models with and without TPA were determined. Results: The stress and displacement plots in this study failed to show any significant differences in stress and displacement within the periodontium of molars, between the two models – one with TPA and the other without, in response to the orthodontic force. Interpretation and Conclusion: The results of the current finite element analysis, therefore, suggest that the presence of a TPA brings about no change in the initial dental and periodontal stress distribution and displacement.

  3. The G Protein-Coupled Estrogen Receptor-1, GPER-1, Promotes Fibrillogenesis via a Shc-Dependent Pathway Resulting in Anchorage-Independent Growth

    Science.gov (United States)

    Magruder, Hilary T.; Quinn, Jeffrey A.; Schwartzbauer, Jean E.; Reichner, Jonathan; Huang, Allan

    2016-01-01

    The G protein-coupled estrogen receptor-1, GPER-1, coordinates fibronectin (FN) matrix assembly and release of heparan-bound epidermal growth factor (HB-EGF). This mechanism of action results in the recruitment of FN-engaged integrin α5β1 to fibrillar adhesions and the formation of integrin α5β1-Shc adaptor protein complexes. Here, we show that GPER-1 stimulation of murine 4 T1 or human SKBR3 breast cancer cells with 17β-estradiol (E2β) promotes the formation of focal adhesions and actin stress fibers and results in increased cellular adhesion and haptotaxis on FN, but not collagen. These actions are also induced by the xenoestrogen, bisphenol A, and the estrogen receptor (ER) antagonist, ICI 182, 780, but not the inactive stereoisomer, 17α-estradiol (E2α). In addition, we show that GPER-1 stimulation of breast cancer cells allows for FN-dependent, anchorage-independent growth and FN fibril formation in “hanging drop” assays, indicating that these GPER-1-mediated actions occur independently of adhesion to solid substrata. Stable expression of Shc mutant Y317F lacking its primary tyrosyl phosphorylation site disrupts E2β-induced focal adhesion and actin stress fiber formation and abolishes E2β-enhanced haptotaxis on FN and anchorage-dependent growth. Collectively, these data demonstrate that E2β action via GPER-1 enhances cellular adhesivity and FN matrix assembly and allows for anchorage-independent growth, cellular events that may allow for cellular survival, and tumor progression. PMID:25096985

  4. Clinical study of temporary anchorage devices for orthodontic treatment--stability of micro/mini-screws and mini-plates: experience with 455 cases.

    Science.gov (United States)

    Takaki, Takashi; Tamura, Naoki; Yamamoto, Masae; Takano, Nobuo; Shibahara, Takahiko; Yasumura, Toshihiko; Nishii, Yasushi; Sueishi, Kenji

    2010-01-01

    The aim of this retrospective study was to determine factors that might cause complications in use of temporary anchorage devices (TADs) for orthodontic anchorage. We investigated 904 TADs in 455 patients. Clinical diagnoses requiring orthodontic treatment were malocclusion, jaw deformity, various syndromes, cleft lip and palate and impacted teeth. All patients underwent surgery at Tokyo Dental College Chiba Hospital between November 2000 and June 2009. Three kinds of titanium screw of different diameter and length were used: self-drilling mini-screws (Dual Top Autoscrew® and OSAS®), pre-drilling micro-screws (K1 system®) and palatal screws (PIAS®). Mini-plates fixed with 2 or 3 screws (SAS system®) were also used for skeletal anchorage. Patients were aged between 8 and 68 years (25.7±9.8 years). A total of 460 screw-type and 444 plate-type TADs were used. These comprised the following: mini-plates, 444; self-drilling mini-screws, 225; pre-drilling micro-screws, 83; and palatal screws, 152. Each type of implant had a high success rate of over about 90%. Failure rates were as follows: micro-screws, 7%; mini-screws, 6%; palatal implants, 11%; and mini-plates, 6%. Inflammation rate occurring in soft tissue surrounding TADs was follows: plate-type, 7.6%; mini-screws, 1.3%; micro-screws, 0%; and palatal implants, 2.5%. Inflammation frequencies depended on degree of mucosal penetration. Granulation rate in soft tissue surrounding TADs occurred as follows: micro-screws, 5.7%; self-drilling mini-screws, 0%; palatal screws, 0.6%; plate-type, 0.9%. Both plate- and screwtype orthodontic implants showed excellent clinical performance.

  5. Thermal Pollution Mathematical Model. Volume 6; Verification of Three-Dimensional Free-Surface Model at Anclote Anchorage; [environment impact of thermal discharges from power plants

    Science.gov (United States)

    Lee, S. S.; Sengupta, S.; Tuann, S. Y.; Lee, C. R.

    1980-01-01

    The free-surface model presented is for tidal estuaries and coastal regions where ambient tidal forces play an important role in the dispersal of heated water. The model is time dependent, three dimensional, and can handle irregular bottom topography. The vertical stretching coordinate is adopted for better treatment of kinematic condition at the water surface. The results include surface elevation, velocity, and temperature. The model was verified at the Anclote Anchorage site of Florida Power Company. Two data bases at four tidal stages for winter and summer conditions were used to verify the model. Differences between measured and predicted temperatures are on an average of less than 1 C.

  6. Treatment of Class II malocclusion with bialveolar protrusion by means of unusual extractions and anchorage mini-implant

    Directory of Open Access Journals (Sweden)

    Jong-Moon Chae

    2012-10-01

    Full Text Available INTRODUCTION: Patients with dental Class II bialveolar protrusion are generally treated by extracting the four first premolars or two first and two second premolars, and retracting the anterior teeth. This case report describes the treatment of an adult patient with bialveolar protrusion, a Class II canine and molar relationship, and lip protrusion. METHODS: In this patient, the maxillary right second molar (1.7 had to be extracted due to extensive caries. To create sufficient space to retract the anterior teeth, the maxillary right posterior teeth were distalized with a maxillary posterior mini-implant (1.2~1.3 mm in diameter, 10 mm long, which was placed into the maxillary tuberosity area and allowed an en masse retraction of the maxillary anterior teeth. RESULTS: Overall, mini-implant can provide anchorage to produce a good facial profile even without additional premolar extraction in cases of dental Class II bialveolar protrusion with the hopeless second molar. CONCLUSION: The total treatment period was 42 months and the results were acceptable for 34 months after debonding.INTRODUÇÃO: os pacientes com Classe II e biprotrusão alveolar são, geralmente, tratados com extração de quatro primeiros pré-molares ou dois primeiros e dois segundos pré-molares, e retração dos dentes anteriores. Este relato de caso descreve o tratamento de um paciente adulto com biprotrusão alveolar, relação de caninos e de molares em Classe II e protrusão labial. MÉTODOS: nesse paciente, o segundo molar superior direito precisou ser extraído devido a cáries extensas. Para criar espaço suficiente para retração dos dentes anteriores, os dentes posterossuperiores direitos foram distalizados com um mini-implante posterossuperior (1,2 ~ 1,3mm de diâmetro, 10mm de comprimento, que foi colocado na área da tuberosidade maxilar e permitiu uma retração em massa dos dentes anteriores. RESULTADOS: em geral, mini-implantes podem fornecer ancoragem para

  7. Anchorage in concrete construction

    CERN Document Server

    Eligehausen, Rolf; Silva, John F

    2013-01-01

    A comprehensive treatment of current fastening technology using inserts (anchor channels, headed stud), anchors (metal expansion anchor, undercut anchor, bonded anchor, concrete screw and plastic anchor) as well as power actuated fasteners in concrete. It describes in detail the fastening elements as well as their effects and load-bearing capacities in cracked and non-cracked concrete. It further focuses on corrosion behaviour, fire resistance and characteristics with earthquakes and shocks. It finishes off with the design of fastenings according to the European Technical Approval Guideline (ETAG 001), the Final Draft of the CEN Technical Specification 'Design of fastenings for use in concrete' and the American Standards ACI 318-05, Appendix D and ACI 349-01, Appendix B.

  8. Anchorages - USACE IENC

    Data.gov (United States)

    Department of Homeland Security — These inland electronic Navigational charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  9. A role for Mfb1p in region-specific anchorage of high-functioning mitochondria and lifespan in Saccharomyces cerevisiae

    Science.gov (United States)

    Pernice, Wolfgang M.; Vevea, Jason D.; Pon, Liza A.

    2016-01-01

    Previous studies indicate that replicative lifespan in daughter cells of Sacchraromyces cerevisiae depends on the preferential inheritance of young, high-functioning mitochondria. We report here that mitochondria are functionally segregated even within single mother cells in S. cerevisiae. A high-functioning population of mitochondria accumulates at the tip of the mother cell distal to the bud. We find that the mitochondrial F-box protein (Mfb1p) localizes to mitochondria in the mother tip and is required for mitochondrial anchorage at that site, independent of the previously identified anchorage protein Num1p. Deletion of MFB1 results in loss of the mother-tip-localized mitochondrial population, defects in mitochondrial function and premature replicative ageing. Inhibiting mitochondrial inheritance to buds, by deletion of MMR1, in mfb1Δ cells restores mitochondrial distribution, promotes mitochondrial function and extends replicative lifespan. Our results identify a mechanism that retains a reservoir of high-functioning mitochondria in mother cells and thereby preserves maternal reproductive capacity. PMID:26839174

  10. Fibronectin has a dual role in locomotion and anchorage of primary chick fibroblasts and can promote entry into the division cycle

    DEFF Research Database (Denmark)

    Couchman, J R; Rees, D A; Green, M R

    1982-01-01

    Fibronectin (FN), which is already known to be a natural factor for fibroblast spreading on substrata, has now been shown to be essential for two distinct types of adhesion with different biological functions in chick heart fibroblasts, namely adhesion directed toward locomotion and toward statio...... for stationary anchorage can be dramatically enhanced by addition of cell-derived FN at an appropriate stage, and this promotes entry into the growth cycle. New macromolecular synthesis in addition to FN is necessary for focal adhesion development but not for locomotion....... stationary anchorage for growth. Manipulation of culture conditions and the use of antisera of differing specificities has demonstrated that both exogenous and cell-derived FN are important in each process. The organization of the fibronectin-containing matrix differs between the two states. Immunoelectron...... microscopy with a colloidal gold marker reveals the presence of small membrane-associated plaques of fibronectin in motile cells with associated submembranous specialization. A fibrillar matrix containing fibronectin is dominant in nonmotile, growing fibroblasts. The development of focal adhesions...

  11. Comparative study of the anchorage and the catalytic properties of nanoporous TiO2 films modified with ruthenium (II) and rhenium (I) carbonyl complexes

    Science.gov (United States)

    Oyarzún, Diego P.; Chardon-Noblat, Sylvie; Linarez Pérez, Omar E.; López Teijelo, Manuel; Zúñiga, César; Zarate, Ximena; Shott, Eduardo; Carreño, Alexander; Arratia-Perez, Ramiro

    2018-02-01

    In this article we study the anchoring of cis-[Ru(bpyC4pyr)(CO)2(CH3CN)2]2+, cis-[Ru(bpy)2(CO)2]2+ and cis-[Ru(bpyac)(CO)2Cl2], onto nanoporous TiO2 employing electropolymerization, electrostatic interaction and chemical bonding. Also, the [Re(bpyac)(CO)3Cl] rhenium(I) complex for chemical anchorage was analyzed. The characterization of TiO2/Ru(II) and TiO2/Re(I) nanocomposite films was performed by field emission scanning electron microscopy (FESEM), electron dispersive X-ray spectroscopy (EDS) and Raman spectroscopy. In addition, for the more stable nanocomposites obtained, the catalytic properties (solar energy conversion and CO2 reduction) were evaluated. The efficiency improvement in redox process derived from the (photo)electrochemical evidence indicates that modified nanoporous TiO2 structures enhance the rate of charge transfer reactions.

  12. MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth.

    Directory of Open Access Journals (Sweden)

    Colin Moore

    Full Text Available Ewing Sarcoma is an aggressive, oncofusion-driven, malignant neoplasm of bone and soft tissue affecting predominantly children and young adults. Seeking to identify potential novel therapeutic targets/agents for this disease, our previous studies uncovered microRNAs regulated by EWS/Fli1, the most common oncofusion, with growth modulatory properties. In the present study, we sought to identify EWS/Fli1-repressed, growth suppressive, microRNAs potentially amenable to replacement in Ewing Sarcoma cells. Eight microRNAs (143, 153, 184, 193b, 195, 203, 206 and 223 were selected for evaluation as EWS/Fli1-repressed and underexpressed in Ewing Sarcoma cells, and reported to be growth suppressive in other pediatric or/and adult cancers. The selected miRs, and appropriate non-targeting controls, were introduced into two different Ewing Sarcoma cell lines (A673 and SK-ES-1, and effects on growth were examined using a high and low-density growth assay. MiR-193b was growth inhibitory in both assays and cell lines. In subsequent analyses, we found that stable overexpression of miR-193b also inhibits anchorage-independent growth in both A673 and SK-ES-1 cells. We further show that miR-193b negatively regulates expression of the ErbB4 oncogene in A673 and SK-ES-1 cells, and that depletion of ErbB4 is itself inhibitory to anchorage-independent growth in the same cell lines. Together, our studies show that the EWS/Fli1-repressed miR-193b is growth suppressive in Ewing Sarcoma, and identify ErbB4 as a target gene and candidate mediator of this growth suppression.

  13. En-masse retraction with a preformed nickel-titanium and stainless steel archwire assembly and temporary skeletal anchorage devices without posterior bonding.

    Science.gov (United States)

    Jee, Jeong-Hyun; Ahn, Hyo-Won; Seo, Kyung-Won; Kim, Seong-Hun; Kook, Yoon-Ah; Chung, Kyu-Rhim; Nelson, Gerald

    2014-09-01

    To evaluate the therapeutic effects of a preformed assembly of nickel-titanium (NiTi) and stainless steel (SS) archwires (preformed C-wire) combined with temporary skeletal anchorage devices (TSADs) as the sole source of anchorage and to compare these effects with those of a SS version of C-wire (conventional C-wire) for en-masse retraction. Thirty-one adult female patients with skeletal Class I or II dentoalveolar protrusion, mild-to-moderate anterior crowding (3.0-6.0 mm), and stable Class I posterior occlusion were divided into conventional (n = 15) and preformed (n = 16) C-wire groups. All subjects underwent first premolar extractions and en-masse retraction with pre-adjusted edgewise anterior brackets, the assigned C-wire, and maxillary C-tubes or C-implants; bonded mesh-tube appliances were used in the mandibular dentition. Differences in pretreatment and post-retraction measurements of skeletal, dental, and soft-tissue cephalometric variables were statistically analyzed. Both groups showed full retraction of the maxillary anterior teeth by controlled tipping and space closure without altered posterior occlusion. However, the preformed C-wire group had a shorter retraction period (by 3.2 months). Furthermore, the maxillary molars in this group showed no significant mesialization, mesial tipping, or extrusion; some mesialization and mesial tipping occurred in the conventional C-wire group. Preformed C-wires combined with maxillary TSADs enable simultaneous leveling and space closure from the beginning of the treatment without maxillary posterior bonding. This allows for faster treatment of dentoalveolar protrusion without unwanted side effects, when compared with conventional C-wire, evidencing its clinical expediency.

  14. En-masse retraction with a preformed nickel-titanium and stainless steel archwire assembly and temporary skeletal anchorage devices without posterior bonding

    Science.gov (United States)

    Jee, Jeong-Hyun; Ahn, Hyo-Won; Seo, Kyung-Won; Kook, Yoon-Ah; Chung, Kyu-Rhim; Nelson, Gerald

    2014-01-01

    Objective To evaluate the therapeutic effects of a preformed assembly of nickel-titanium (NiTi) and stainless steel (SS) archwires (preformed C-wire) combined with temporary skeletal anchorage devices (TSADs) as the sole source of anchorage and to compare these effects with those of a SS version of C-wire (conventional C-wire) for en-masse retraction. Methods Thirty-one adult female patients with skeletal Class I or II dentoalveolar protrusion, mild-to-moderate anterior crowding (3.0-6.0 mm), and stable Class I posterior occlusion were divided into conventional (n = 15) and preformed (n = 16) C-wire groups. All subjects underwent first premolar extractions and en-masse retraction with pre-adjusted edgewise anterior brackets, the assigned C-wire, and maxillary C-tubes or C-implants; bonded mesh-tube appliances were used in the mandibular dentition. Differences in pretreatment and post-retraction measurements of skeletal, dental, and soft-tissue cephalometric variables were statistically analyzed. Results Both groups showed full retraction of the maxillary anterior teeth by controlled tipping and space closure without altered posterior occlusion. However, the preformed C-wire group had a shorter retraction period (by 3.2 months). Furthermore, the maxillary molars in this group showed no significant mesialization, mesial tipping, or extrusion; some mesialization and mesial tipping occurred in the conventional C-wire group. Conclusions Preformed C-wires combined with maxillary TSADs enable simultaneous leveling and space closure from the beginning of the treatment without maxillary posterior bonding. This allows for faster treatment of dentoalveolar protrusion without unwanted side effects, when compared with conventional C-wire, evidencing its clinical expediency. PMID:25309863

  15. Exposure to bisphenol A correlates with early-onset prostate cancer and promotes centrosome amplification and anchorage-independent growth in vitro.

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    Pheruza Tarapore

    Full Text Available Human exposure to bisphenol A (BPA is ubiquitous. Animal studies found that BPA contributes to development of prostate cancer, but human data are scarce. Our study examined the association between urinary BPA levels and Prostate cancer and assessed the effects of BPA on induction of centrosome abnormalities as an underlying mechanism promoting prostate carcinogenesis. The study, involving 60 urology patients, found higher levels of urinary BPA (creatinine-adjusted in Prostate cancer patients (5.74 µg/g [95% CI; 2.63, 12.51] than in non-Prostate cancer patients (1.43 µg/g [95% CI; 0.70, 2.88] (p = 0.012. The difference was even more significant in patients <65 years old. A trend toward a negative association between urinary BPA and serum PSA was observed in Prostate cancer patients but not in non-Prostate cancer patients. In vitro studies examined centrosomal abnormalities, microtubule nucleation, and anchorage-independent growth in four Prostate cancer cell lines (LNCaP, C4-2, 22Rv1, PC-3 and two immortalized normal prostate epithelial cell lines (NPrEC and RWPE-1. Exposure to low doses (0.01-100 nM of BPA increased the percentage of cells with centrosome amplification two- to eight-fold. Dose responses either peaked or reached the plateaus with 0.1 nM BPA exposure. This low dose also promoted microtubule nucleation and regrowth at centrosomes in RWPE-1 and enhanced anchorage-independent growth in C4-2. These findings suggest that urinary BPA level is an independent prognostic marker in Prostate cancer and that BPA exposure may lower serum PSA levels in Prostate cancer patients. Moreover, disruption of the centrosome duplication cycle by low-dose BPA may contribute to neoplastic transformation of the prostate.

  16. Movimentação de molares inferiores ancorados em mini-parafusos Mandibular molar uprighting, using mini-screw as anchorage

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    Rosana Canteras Di Matteo

    2005-08-01

    Full Text Available Freqüentemente a movimentação ortodôntica exige recursos adicionais de ancoragem. Os mini-parafusos têm-se apresentado como uma possível solução. O propósito deste trabalho foi estabelecer um método para a verticalização de molares inferiores inclinados para mesial, utilizando ancoragem em mini-parafusos colocados na região de linha oblíqüa externa da mandíbula. Foram selecionados três pacientes entre 40 a 48 anos (dois do gênero feminino, um do gênero masculino, com molares inferiores inclinados para mesial e distalmente posicionados às áreas edêntulas. Os pacientes foram tratados ortodonticamente durante um período de 6 a 12 meses, com técnica ortodôntica MD3. Mini-parafusos de titânio foram colocados bilateralmente com anestesia local. Uma incisão sobre a linha oblíqüa externa da mandíbula, medindo aproximadamente 1 cm foi realizada em cada lado, distalmente aos molares inclinados. Após descolamento muco-periosteal, mini-parafusos foram implantados e foram realizadas suturas deixando suas cabeças exteriorizadas. Uma semana após a remoção das suturas, cargas ortodônticas (entre 150 a 200 gramas/força foram aplicadas através de forças elásticas. Verificamos que alguma inflamação foi observada ao redor dos mini-parafusos, mas foi controlada com procedimentos de higienização. O procedimento cirúrgico é simples, podendo ser realizado pelo ortodontista; as formas dimensionais dos mini-parafusos são adequadas e estes são de fácil remoção após uso. Concluímos que o uso de mini-parafusos representa uma alternativa efetiva de ancoragem ortodôntica na verticalização de molares inferiores.Tooth movement frequently requires additional anchorage resources. Mini-screws have been used as a possible solution to this matter. The purpose of this study was to establish a method of mandibular molar uprighting, using mini-screw as anchorage, positioned on the mandibular external oblique line, behind and

  17. Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance.

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    Abou-Antoun, Tamara J; Nazarian, Javad; Ghanem, Anthony; Vukmanovic, Stanislav; Sandler, Anthony D

    2018-01-01

    Despite significant advances in cancer treatment and management, more than 60% of patients with neuroblastoma present with very poor prognosis in the form of metastatic and aggressive disease. Solid tumors including neuroblastoma are thought to be heterogeneous with a sub-population of stem-like cells that are treatment-evasive with highly malignant characteristics. We previously identified a phenomenon of reversible adaptive plasticity (RAP) between anchorage dependent (AD) cells and anchorage independent (AI) tumorspheres in neuroblastoma cell cultures. To expand our molecular characterization of the AI tumorspheres, we sought to define the comprehensive proteomic profile of murine AD and AI neuroblastoma cells. The proteomic profiles of the two phenotypic cell populations were compared to each other to determine the differential protein expression and molecular pathways of interest. We report exclusive or significant up-regulation of tumorigenic pathways expressed by the AI tumorspheres compared to the AD cancer cells. These pathways govern metastatic potential, enhanced malignancy and epithelial to mesenchymal transition. Furthermore, radio-therapy induced significant up-regulation of specific tumorigenic and proliferative proteins, namely survivin, CDC2 and the enzyme Poly [ADP-ribose] polymerase 1. Bio-functional characteristics of the AI tumorspheres were resistant to sutent inhibition of receptor tyrosine kinases (RTKs) as well as to 2.5 Gy radio-therapy as assessed by cell survival, proliferation, apoptosis and migration. Interestingly, PDGF-BB stimulation of the PDGFRβ led to transactivation of EGFR and VEGFR in AI tumorspheres more potently than in AD cells. Sutent inhibition of PDGFRβ abrogated this transactivation in both cell types. In addition, 48 h sutent treatment significantly down-regulated the protein expression of PDGFRβ, MYCN, SOX2 and Survivin in the AI tumorspheres and inhibited tumorsphere self-renewal. Radio-sensitivity in AI

  18. Mesialização de molares com ancoragem em mini-implantes Mesial movement of molars with mini-implants anchorage

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    Marcos Janson

    2008-10-01

    Full Text Available INTRODUÇÃO: é muito comum, na rotina do consultório odontológico, especialmente em Ortodontia, o paciente, após avaliar o plano de tratamento proposto, questionar sobre a possibilidade de fechamento de espaços presentes, ocasionados pela perda de dentes permanentes. O ortodontista, frente a essa questão, tem que avaliar diversos fatores, tais como a má oclusão presente, a integridade do osso e das raízes, o tempo de tratamento e a geometria do posicionamento dentário, que é o que permite avaliar se, com o fechamento dos espaços e, conseqüentemente, a perda de ancoragem dos segmentos anteriores, a finalização estará de acordo com os ideais que regem a especialidade. Com o advento dos mini-implantes, as possibilidades desta abordagem terapêutica aumentaram, pois o efeito adverso da perda de ancoragem pode ser eliminado e, com isso, o paciente pode ser beneficiado. No entanto, os outros fatores envolvidos, assim como a mecânica do movimento, requerem especial atenção. OBJETIVOS: no presente artigo serão abordados os fatores envolvidos neste tipo de tratamento, o raciocínio na tomada de decisões e os detalhes importantes que devem ser observados durante a condução da mecânica, ilustrados com casos clínicos.INTRODUCTION: It's routine, especially at the orthodontic office, the patient, after the assessment of the proposed treatment plan, answer about the possibility of closing their edentulous spaces caused by missed permanent teeth. In these situations, several factors must be evaluated, like the present malocclusion, the bone and roots integrity, the treatment time and the geometry of teeth positioning, that is what permits to assess if the loss of anchorage from the anterior segments, during the space closure, would permit the occlusion to end within the orthodontic ideals. With the mini-implants, the possibilities of this therapeutic approach have been improved, since the adverse effects are eliminated with the

  19. Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance

    Science.gov (United States)

    Nazarian, Javad; Ghanem, Anthony; Vukmanovic, Stanislav; Sandler, Anthony D.

    2018-01-01

    Despite significant advances in cancer treatment and management, more than 60% of patients with neuroblastoma present with very poor prognosis in the form of metastatic and aggressive disease. Solid tumors including neuroblastoma are thought to be heterogeneous with a sub-population of stem-like cells that are treatment-evasive with highly malignant characteristics. We previously identified a phenomenon of reversible adaptive plasticity (RAP) between anchorage dependent (AD) cells and anchorage independent (AI) tumorspheres in neuroblastoma cell cultures. To expand our molecular characterization of the AI tumorspheres, we sought to define the comprehensive proteomic profile of murine AD and AI neuroblastoma cells. The proteomic profiles of the two phenotypic cell populations were compared to each other to determine the differential protein expression and molecular pathways of interest. We report exclusive or significant up-regulation of tumorigenic pathways expressed by the AI tumorspheres compared to the AD cancer cells. These pathways govern metastatic potential, enhanced malignancy and epithelial to mesenchymal transition. Furthermore, radio-therapy induced significant up-regulation of specific tumorigenic and proliferative proteins, namely survivin, CDC2 and the enzyme Poly [ADP-ribose] polymerase 1. Bio-functional characteristics of the AI tumorspheres were resistant to sutent inhibition of receptor tyrosine kinases (RTKs) as well as to 2.5 Gy radio-therapy as assessed by cell survival, proliferation, apoptosis and migration. Interestingly, PDGF-BB stimulation of the PDGFRβ led to transactivation of EGFR and VEGFR in AI tumorspheres more potently than in AD cells. Sutent inhibition of PDGFRβ abrogated this transactivation in both cell types. In addition, 48 h sutent treatment significantly down-regulated the protein expression of PDGFRβ, MYCN, SOX2 and Survivin in the AI tumorspheres and inhibited tumorsphere self-renewal. Radio-sensitivity in AI

  20. Characterization of mutagen-activated cellular oncogenes that confer anchorage independence to human fibroblasts and tumorigenicity to NIH 3T3 cells: Sequence analysis of an enzymatically amplified mutant HRAS allele

    International Nuclear Information System (INIS)

    Stevens, C.W.; Manoharan, T.H.; Fahl, W.E.

    1988-01-01

    Treatment of diploid human fibroblasts with an alkylating mutagen has been shown to induce stable, anchorage-independent cell populations at frequencies consistent with an activating mutation. After treatment of human foreskin fibroblasts with the mutagen benzo[α]pyrene (±)anti-7,8-dihydrodiol 9,10-epoxide and selection in soft agar, 17 anchorage-independent clones were isolated and expanded, and their cellular DNA was used to cotransfect NIH 3T3 cells along with pSV2neo. DNA from 11 of the 17 clones induced multiple NIH 3T3 cell tumors in recipient nude mice. Southern blot analyses showed the presence of human Alu repetitive sequences in all of the NIH 3T3 tumor cell DNAs. Intact, human HRAS sequences were observed in 2 of the 11 tumor groups, whereas no hybridization was detected when human KRAS or NRAS probes were used. Slow-migrating ras p21 proteins, consistent with codon 12 mutations, were observed in the same two NIH 3T3 tumor cell groups that contained the human HRAS bands. Genomic DNA from one of these two human anchorage-independent cell populations (clone 21A) was used to enzymatically amplify a portion of exon 1 of the HRAS gene. The results demonstrate that exposure of normal human cells to a common environmental mutagen yields HRAS GC → TA codon 12 transversions that have been commonly observed in human tumors

  1. Induction of anchorage-independent growth in primary human cells exposed to protons or HZE ions separately or in dual exposures.

    Science.gov (United States)

    Sutherland, B M; Cuomo, N C; Bennett, P V

    2005-10-01

    Travelers on space missions will be exposed to a complex radiation environment that includes protons and heavy charged particles. Since protons are present at much higher levels than are heavy ions, the most likely scenario for cellular radiation exposure will be proton exposure followed by a hit by a heavy ion. Although the effects of individual ion species on human cells are being investigated extensively, little is known about the effects of exposure to both radiation types. One useful measure of mammalian cell damage is induction of the ability to grow in a semi-solid agar medium highly inhibitory to the growth of normal human cells, termed neoplastic transformation. Using primary human cells, we evaluated induction of soft-agar growth and survival of cells exposed to protons only or to heavy charged particles (600 MeV/nucleon silicon) only as well as of cells exposed to protons followed after a 4-day interval by silicon ions. Both ions alone efficiently transformed the human cells to anchorage-independent growth. Initial experiments indicate that the dose responses for neoplastic transformation of cells exposed to protons and then after 4 days to silicon ions appear similar to that of cells exposed to silicon ions alone.

  2. Cellular Dichotomy Between Anchorage-Independent Growth Responses to bFGF and TA Reflects Molecular Switch in Commitment to Carcinogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Waters, Katrina M.; Tan, Ruimin; Opresko, Lee K.; Quesenberry, Ryan D.; Bandyopadhyay, Somnath; Chrisler, William B.; Weber, Thomas J.

    2009-11-01

    We have investigated gene expression patterns underlying reversible and irreversible anchorage-independent growth (AIG) phenotypes to identify more sensitive markers of cell transformation for studies directed at interrogating carcinogenesis responses. In JB6 mouse epidermal cells, basic fibroblast growth factor (bFGF) induces an unusually efficient and reversible AIG response, relative to 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced AIG which is irreversible. The reversible and irreversible AIG phenotypes are characterized by largely non-overlapping global gene expression profiles. However, a subset of differentially expressed genes were identified as common to reversible and irreversible AIG phenotypes, including genes regulated in a reciprocal fashion. Hepatic leukemia factor (HLF) and D-site albumin promoter-binding protein (DBP) were increased in both bFGF and TPA soft agar colonies and selected for functional validation. Ectopic expression of human HLF and DBP in JB6 cells resulted in a marked increase in TPA- and bFGF-regulated AIG responses. HLF and DBP expression were increased in soft agar colonies arising from JB6 cells exposed to gamma radiation and in a human basal cell carcinoma tumor tissue, relative to paired non-tumor tissue. Subsequent biological network analysis suggests that many of the differentially expressed genes that are common to bFGF- and TPA-dependent AIG are regulated by c-Myc, SP-1 and HNF-4 transcription factors. Collectively, we have identified a potential molecular switch that mediates the transition from reversible to irreversible AIG.

  3. Evaluation of stress patterns on maxillary posterior segment when intruded with mini implant anchorage: A three-dimensional finite element study

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    Nikhita Pekhale

    2016-01-01

    Full Text Available Introduction: The aim of this study is to evaluate stress and displacement effects of maxillary posterior intrusion mechanics with mini-implant anchorage by using finite element method. Materials and Methods: A computer stimulation of three-dimensional model maxilla with all teeth, PDL, bone, mini-implants, brackets, arch wire, force element, and transpalatal arch was constructed on the basis of average anatomic morphology. Finite element analysis was done to evaluate the amount of stress and its distribution during orthodontic intrusive force. Results: Increased Von Mises stress values were observed in mesio-cervical region of first molar. The middle third of second premolar and second molar and regions adjacent to force application sites also showed relatively high stress values. Minimum stress values were observed in apical region of first premolar as it is away from force application. Conclusion: Using three mini-implant and transpalatal arches, this study demonstrates that significant amount of true intrusion of maxillary molars could be obtained with lesser concentration of stresses in the apical area recorded.

  4. [Extensometry and primary anchorage of femur implants. Study of the upper metaphyseal intracortical support of the B.P.R cement-less implant].

    Science.gov (United States)

    Delecrin, J; Passuti, N; Royer, J; Rogez, J M; Bainvel, J V

    1989-01-01

    This study uses extensometry to compare the distribution of strain on a fresh femur before and after implantation of various titanium prostheses: one is a cementless implant with metaphyseal endosteal support; the second is a cemented prosthesis with and without calcar collar contact; the last is a titanium implant with fixation by screens. The precision of the measurements have been improved particularly in the proximal metaphyseal area using bidirectional gauges. The system of loading permits comparison of the different implants and the results obtained with the B.P.R. prosthesis compared with the cemented implant without calcar contact are very close. The effect of the collar appears very limited despite the optimal conditions of the in vivo implantation that improve the calcar-collar contact. The screw implant increases the stress shielding of the proximal area of the femur. The different steps of the experiment illustrate the strain distribution in relation to the implantation of the devices and the contact bone prosthesis. The significant endosteal fixation of the B.P.R. prosthesis in the proximal metaphyseal area allows a better primary anchorage which increases distribution of the stress and therefore results in better secondary fixation by bony ingrowth.

  5. A novel gelatin-based micro-cavitary hydrogel for potential application in delivery of anchorage dependent cells: A study with vasculogenesis model.

    Science.gov (United States)

    Leong, Wenyan; Fan, Changjiang; Wang, Dong-An

    2016-10-01

    Hydrogels have been widely regarded as promising tissue engineering scaffolds and cell delivery vehicles, however, their inherent submicron- or nano-scale polymer networks severely inhibit the settlement of anchorage dependent cells (ADCs). Here, using endothelial progenitor outgrowth cells (EPOCs) as the typical ADCs, a gelatin-based micro-cavitary gel (namely Gel-MCG) is developed with gelatin-methacrylate and gelatin microspheres as precursor and porogens, respectively, to promote cellular focal adhesion and functions. The introduction of micro-cavitary structures within the Gel-MCG improves its physical properties as well as creates numerous gel-microcavity interfaces within gel-based matrices. Compared with conventional gelatin gel (Gel-G) scaffold, the Gel-MCG provides more suitable microenvironments for EPOCs' attachment, spreading, and proliferation, and then which leads to enhanced endothelial differentiation and vascularization as demonstrated by higher expressions of endothelial markers. The Gel-MCG system shows great potential as vehicle for the delivery of ADCs in tissue engineering. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Automation of the Design of the Anchorage System Taking into Account the Geomechanical State of the Massif and Mining Development Schemes

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    Demin Vladimir

    2018-01-01

    Full Text Available The article presents the system for the automation of the design of the anchorage, which regulates the calculation of the required parameters of the fasteners for the fastening of the fastening system. The main factors affecting the operation of the anchor support are grouped in the following way: mining and geological conditions, technical characteristics of the anchor support, geomechanical conditions for conducting and operating the mine workings. Mining and geological conditions for carrying out excavations include: physical and mechanical properties of rocks, the category of roof stability, fracturing, etc. Technical characteristics of the anchor support: material of the rod, filler, filling completeness, etc. Conditions (geomechanical of carrying out and exploitation of the mine workings: the depth of the conduct, the location relative to the zone of influence of the cleaning works, the location relative to the waste zone, etc. As a result of calculations the program gives out the basic parameters of the anchor support, which coincide with the parameters adopted by the passport.

  7. Is pelvic fixation the only option to provide additional stability to the sacral anchorage in long lumbar instrumentation? A comparative biomechanical study of new techniques.

    Science.gov (United States)

    Volkheimer, David; Reichel, Heiko; Wilke, Hans-Joachim; Lattig, Friederike

    2017-03-01

    Supplementary iliac screws have the highest potential to protect S1-pedicle-screws from loosening in long fusion constructs. However, this technique bridges the iliosacral joint with potential disadvantages for the patient. This study aimed to evaluate if two different established fixation techniques can be used in addition to pedicle screws as alternative to iliac screws, and if these two techniques can provide similar stability when S1-pedicle-screws are loosened. Flexibility testing with pure moments of 7.5Nm was performed with six human osteopenic/osteoporotic L4-pelvis specimens. The following conditions were investigated: 1. Intact; 2. Destabilization L5/S1; 3. Fixation with rigid L4-S1 pedicle-screw-system; 4. Condition 3- loosening of S1-screws; 5. Condition 4- L5-S2-lamina-hooks; 6. Condition 4- L5/S1-translaminar-screws; 7. Condition 4- S2-ala-ilium screws. Application of compressive L5-S2-lamina-hooks or L5/S1-translaminar-screws next to pedicle screws in L5 and S1 was feasible in all specimens. L4-S1-pedicle-screw-instrumentation reduced the Range of Motion significantly compared to the destabilized condition. After simulation of S1 screw loosening, lamina hooks only reduced the Range of Motion in flexion/extension significantly. L5/S1-translaminar-screws had a higher stabilizing effect in lateral bending and axial rotation, but the effect of both systems was smaller than with an instrumentation extension to the os ilium. In long lumbar pedicle screw instrumentations including L5/S1, additional ilium screws have the highest potential to protect the S1-anchorage. Additional L5/S1-translaminar-screws can increase stability of the lumbosacral junction without bridging the iliosacral joint, whereas lamina hooks showed no significant biomechanical benefit. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. The quantity of bone cement influences the anchorage of augmented pedicle screws in the osteoporotic spine: A biomechanical human cadaveric study.

    Science.gov (United States)

    Pishnamaz, Miguel; Lange, Henning; Herren, Christian; Na, Hong-Sik; Lichte, Philipp; Hildebrand, Frank; Pape, Hans-Christoph; Kobbe, Philipp

    2018-02-01

    The aim of this comparative biomechanical human cadaveric study was to investigate the anchorage of augmented screws with two different volumes of bone cement. For this purpose the effect of cranio-caudal loadings on pedicle screws was evaluated and axial pullout tests were performed. A total of 50 pedicle screws (25 augmented/25 non-augmented) were instrumented into osteoporotic vertebra of fresh human cadavers. The augmented screws were grounded by two different volumes of bone cement (1.5cm 3 vs 4cm 3 ). Biomechanical performance was assessed by performing a cyclic loading protocol (frequency: 3Hz, load range: 20-200N, number of cycles: 100,000), followed by axial pullout (13 augmented/11 non-augmented) or by either directly measuring axial pullout strength (12 augmented/12 non-augmented). The median T-score of the specimens was -4.25 (range: -6.38 to -2.4). Pullout tests with and without cyclic preloading showed significantly increased pullout strength in augmented screws (Fmax: augmented: 1159N (SD 395N); non-augmented: 532N (SD 297N); p0.05). The pullout strength significantly decreased in high-volume augmented screws after cyclic loading (Fmax (4.0cm 3 ): direct pullout 1463N (SD 307N); cyclic preload: 902N (SD 435N); p<0.05). Biomechanical advantages of augmented pedicle screws can also be found after cyclic preload. However, our results indicate that the anchoring stability of high-volume augmented pedicle screws after cyclic loading is disadvantageous compared to moderate augmented screws; thus high-volume augmentation should be avoided. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Abduction of Toe-excavation Induced Failure Process from LEM and FDM for a Dip Slope with Rock Anchorage in Taiwan

    Science.gov (United States)

    Huang, W.-S.; Lin, M.-L.; Liu, H.-C.; Lin, H.-H.

    2012-04-01

    On April 25, 2010, without rainfall and earthquake triggering a massive landslide (200000 m3) covered a 200m stretch of Taiwan's National Freeway No. 3, killing 4 people, burying three cars and destroying a bridge. The failure mode appears to be a dip-slope type failure occurred on a rock anchorage cut slope. The strike of Tertiary sedimentary strata is northeast-southwest and dip 15˚ toward southeast. Based on the investigations of Taiwan Geotechnical Society, there are three possible factors contributing to the failure mechanism as follow:(1) By toe-excavation during construction in 1998, the daylight of the sliding layer had induced the strength reduction in the sliding layer. It also caused the loadings of anchors increased rapidly and approached to their ultimate capacity; (2) Although the excavated area had stabilized soon with rock anchors and backfills, the weathering and groundwater infiltration caused the strength reduction of overlying rock mass; (3) The possible corrosion and age of the ground anchors deteriorate the loading capacity of rock anchors. Considering the strength of sliding layer had reduced from peak to residual strength which was caused by the disturbance of excavation, the limit equilibrium method (LEM) analysis was utilized in the back analysis at first. The results showed the stability condition of slope approached the critical state (F.S.≈1). The efficiency reduction of rock anchors and strength reduction of overlying stratum (sandstone) had been considered in following analysis. The results showed the unstable condition (F.S. <1). This research also utilized the result of laboratory test, geological strength index(GSI) and finite difference method (FDM, FLAC 5.0) to discuss the failure process with the interaction of disturbance of toe-excavation, weathering of rock mass, groundwater infiltration and efficiency reduction of rock anchors on the stability of slope. The analysis indicated that the incremental load of anchors have

  10. Caracterização de mini-implantes utilizados na ancoragem ortodôntica Characterization of the mini-implants used to orthodontic anchorage

    Directory of Open Access Journals (Sweden)

    Luciana Rougemont Squeff

    2008-10-01

    Full Text Available INTRODUÇÃO: o diâmetro reduzido do mini-implante, e a decorrente facilidade na sua inserção, minimizam a possibilidade de erro do operador e de contato entre a rosca do mini-implante e a raiz dentária. Entretanto, o risco de fratura da peça aumenta à medida que seu diâmetro é diminuído. MÉTODOS: neste trabalho foram analisados quatro produtos de marcas nacionais (INP, SIN, Conexão e Neodente e um de marca alemã (Mondeal, com o objetivo de identificar características importantes para o bom desempenho deste recurso como acessório de ancoragem. Foram observados composição e design das peças e realizado o ensaio mecânico de torque até a fratura (estudo in vitro, cujos valores foram submetidos à análise de variância (ANOVA e teste de Tukey. RESULTADOS: os resultados mostraram que todos os mini-implantes testados estão aptos à utilização clínica como reforço de ancoragem ortodôntica.INTRODUCTION: The reduced diameter of the mini-implants and the simplicity of the technique could minimize the operator mistake's possibility and avoid the contact between the thread of the screw and the dental root. In spite of that, it increases the fracture risk because of the diameter's decrease. METHODS: At the present work, mini-implants from five different trade marks, four Brazilian systems (INP, SIN, Conexão and Neodente and a German system (Mondeal were studied to identify important characteristics of this anchorage accessory, like composition, design and resistance to the insertion torque (in vitro. The values obtained from the mechanical torque test were submitted to variance analysis (ANOVA and Tukey's test. RESULTS: All studied groups presented good results and are recommended to orthodontic clinic use.

  11. Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate

    Directory of Open Access Journals (Sweden)

    Hsiu-Man Lien

    2011-01-01

    Full Text Available In this study, 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1 was isolated from three different sources of dried fruiting bodies of Antrodia camphorate (AC. AC is a medicinal mushroom that grows on the inner heartwood wall of Cinnamomum kanehirai Hay (Lauraceae, an endemic species that is used in Chinese medicine for its anti-tumor and immunomodulatory properties. In this study, we demonstrated that SY-1 profoundly decreased the proliferation of human colon cancer cells (COLO 205 through G0/G1 cell-cycle arrest (50–150 μM and induction of apoptosis (>150 μM. Cell-cycle arrest induced by SY-1 was associated with a significant increase in levels of p53, p21/Cip1 and p27/Kip1, and a decrease in cyclins D1, D3 and A. In contrast, SY-1 treatment did not induce significant changes in G0/G1 phase cell-cycle regulatory proteins in normal human colonic epithelial cells (FHC. The cells were cultured in soft agar to evaluate anchorage-independent colony formation, and we found that the number of transformed colonies was significantly reduced in the SY-1-treated COLO 205 cells. These findings demonstrate for the first time that SY-1 inhibits human colon cancer cell proliferation through inhibition of cell growth and anchorage-independent colony formation in soft agar. However, the detailed mechanisms of these processes remain unclear and will require further investigation.

  12. X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis.

    Science.gov (United States)

    Cao, Zipeng; Zhang, Ruowen; Li, Jingxia; Huang, Haishan; Zhang, Dongyun; Zhang, Jingjie; Gao, Jimin; Chen, Jingyuan; Huang, Chuanshu

    2013-07-12

    The X-linked inhibitor of apoptosis protein (XIAP) is a well known potent inhibitor of apoptosis; however, it is also involved in other cancer cell biological behavior. In the current study, we discovered that XIAP and its E3 ligase played a crucial role in regulation of cyclin D1 expression in cancer cells. We found that deficiency of XIAP expression resulted in a marked reduction in cyclin D1 expression. Consistently, cell cycle transition and anchorage-independent cell growth were also attenuated in XIAP-deficient cancer cells compared with those of the parental wild-type cells. Subsequent studies demonstrated that E3 ligase activity within the RING domain of XIAP is crucial for its ability to regulate cyclin D1 transcription, cell cycle transition, and anchorage-independent cell growth by up-regulating transactivation of c-Jun/AP-1. Moreover, we found that E3 ligase within RING domain was required for XIAP inhibition of phosphatase PP2A activity by up-regulation of PP2A phosphorylation at Tyr-307 in its catalytic subunit. Such PP2A phosphorylation and inactivation resulted in phosphorylation and activation of its downstream target c-Jun in turn leading to cyclin D1 expression. Collectively, our studies uncovered a novel function of E3 ligase activity of XIAP in the up-regulation of cyclin D1 expression, providing significant insight into the understanding of the biomedical significance of overexpressed XIAP in cancer development, further offering a new molecular basis for utilizing XIAP E3 ligase as a cancer therapeutic target.

  13. Comparison of in-vivo failure of single-thread and dual-thread temporary anchorage devices over 18 months: A split-mouth randomized controlled trial.

    Science.gov (United States)

    Durrani, Owais Khalid; Shaheed, Sohrab; Khan, Arsalan; Bashir, Ulfat

    2017-10-01

    The purpose of this study was to compare the in-vivo failure rates of single-thread and dual-thread temporary anchorage device (TAD) designs over 18 months. Thirty patients with skeletal Class II Division 1 malocclusion requiring anchorage from TADs for retraction of maxillary incisors into the extracted premolar space were recruited in this parallel group, split-mouth, randomized controlled trial. A block randomization sequence was generated with Random Allocation Software (version 2.0; Isfahan, Iran) with the allocations concealed in sequentially numbered, opaque, sealed envelopes. A total of 60 TADs (diameter, 2 mm; length, 10 mm) were placed in the maxillary arches of these patients with random allocation of the 2 types to the left and the right sides in a 1:1 ratio. All TADs were placed between the roots of the second premolar and the first molar and were immediately loaded. Patients were followed for a minimum of 12 months and a maximum of 18 months for the failure of the TADs. Data were analyzed blindly on an intention-to-treat basis. Four TADs (13.3%) failed in the single-thread group, and 6 TADs (20%) failed in the dual-thread group. The McNemar test showed an insignificant difference (P = 0.72) between the 2 groups. An odds ratio of 1.6 (95% confidence interval, 0.39-6.97) showed no significant associations among the variables. Most TADs failed in the first month after insertion (50%). The failure rate of dual-thread TADs compared with single-thread TADs is statistically insignificant when placed in the maxilla for retraction of the anterior segment. Registration: The trial was not registered before commencement. The protocol was not published before the trial. Copyright © 2016 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  14. Diacylglycerol kinase α mediates 17-β-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30.

    Science.gov (United States)

    Filigheddu, Nicoletta; Sampietro, Sara; Chianale, Federica; Porporato, Paolo E; Gaggianesi, Miriam; Gregnanin, Ilaria; Rainero, Elena; Ferrara, Michele; Perego, Beatrice; Riboni, Francesca; Baldanzi, Gianluca; Graziani, Andrea; Surico, Nicola

    2011-12-01

    Increased levels of endogenous and/or exogenous estrogens are one of the well known risk factors of endometrial cancer. Diacylglycerol kinases (DGKs) are a family of enzymes which phosphorylate diacylglycerol (DAG) to produce phosphatidic acid (PA), thus turning off and on DAG-mediated and PA-mediated signaling pathways, respectively. DGK α activity is stimulated by growth factors and oncogenes and is required for chemotactic, proliferative, and angiogenic signaling in vitro. Herein, using either specific siRNAs or the pharmacological inhibitor R59949, we demonstrate that DGK α activity is required for 17-β-estradiol (E2)-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line. Impairment of DGK α activity also influences basal cell proliferation and growth in soft agar of Hec-1A, while it has no effects on basal cell motility. Moreover, we show that DGK α activity induced by E2, as well as its observed effects, are mediated by the G protein-coupled estrogen receptor GPR30 (GPER). These findings suggest that DGK α may be a potential target in endometrial cancer therapy. Copyright © 2011 Elsevier Inc. All rights reserved.

  15. El fondeadero romano de Isla del Moral y el comercio marítimo en la desembocadura del Guadiana = The Roman anchorage at the island of Moral and the maritime trade in the river mouth of Guadiana

    Directory of Open Access Journals (Sweden)

    Juan Aurelio Pérez Macías

    2014-12-01

    Full Text Available En este trabajo se presentan los resultados de la prospección arqueológica subacuática llevada a cabo en el Río Carreras (Ayamonte, Huelva, España con motivo de su dragado. La localización de un depósito submarino con abundante material arqueológico de época romana, en especial material anfórico, nos lleva a considerar este hallazgo como los restos de un fondeadero cercano al yacimiento romano situado en la Isla del Moral (Ayamonte. El análisis de este material cerámico nos permite reflexionar sobre la posición de este asentamiento de la desembocadura del río Guadiana en el comercio marítimo de las costas atlánticas hispanas, y su verdadero papel para facilitar los abastecimientos e intercambios con las poblaciones del interior en el tráfico fluvial que aprovecha el tramo navegable de este río hasta Mértola (Portugal.This paper presents the results of underwater archaeological survey carried out at the Río Carreras (Ayamonte, Huelva, SW Spain on the occasion of the dredging of the River Race. The location of an underwater deposit with plenty of Roman archaeological material, especially amphorae, leads us to consider this finding as the remains of a Roman site near the anchorage located in Isla del Moral (Ayamonte. The analysis of the pottery allows us to reflect on the position of the settlement of the Guadiana River in the maritime trade of Atlantic coasts, and its true role in facilitating supplies and exchanges with interior populations in river traffic leveraging the navigable stretch of this river to Mértola (Portugal.

  16. Distalização de segundo molar inferior impactado através da utilização de ancoragem esquelética com miniplaca: relato de caso Distalization of impacted mandibular second molar using miniplates for skeletal anchorage: case report

    Directory of Open Access Journals (Sweden)

    Belini Freire-Maia

    2011-08-01

    Full Text Available O presente estudo consiste no relato de um caso onde a distalização do segundo molar inferior impactado do lado direito foi obtida através da ancoragem esquelética com o uso de miniplaca. A verticalização dos segundos molares inferiores impactados, durante muito tempo, colocou-se como um grande desafio para ortodontistas e cirurgiões bucais devido à escassez de recursos de ancoragem destinados para esse fim. A utilização da ancoragem esquelética foi iniciada na clínica ortodôntica em meados dos anos 80 e, desde então, diversas modalidades têm sido desenvolvidas para esse princípio, como a utilização de mini-implantes, implantes dentários e, finalmente, miniplacas, que foram testadas e apresentaram resultados animadores. O assunto é relevante para ortodontistas e cirurgiões bucais, uma vez que o uso das miniplacas pode influir de forma significativa no tratamento de molares inferiores impactados.This study describes a case with an impacted right mandibular second molar which was distalized using miniplates for skeletal anchorage. Uprighting impacted mandibular second molars has been a great challenge for orthodontists and oral surgeons because of the scarcity of anchorage options. Skeletal anchorage was first used in clinical orthodontics in the middle of the 1980s. Since then, several devices have been developed for that purpose, such as mini-screws, tooth implants and, lately, miniplates, which have been tested and showed encouraging results. This topic is relevant for orthodontists and oral surgeons because the use of miniplates may significantly change the treatment of impacted mandibular molars.

  17. 76 FR 76295 - Anchorage Regulations; Wells, ME

    Science.gov (United States)

    2011-12-07

    ... recreational and small fishing vessels intending to anchor in Wells Harbor. The rule will not have a... and other recreational craft. Temporary floats or buoys for marking anchors or moorings in place are...

  18. 76 FR 52599 - Anchorage Regulations; Wells, ME

    Science.gov (United States)

    2011-08-23

    ... Budget has not reviewed it under that Order. We expect minimal additional cost impacts on fishing, or... operators of recreational and small fishing vessels intending to anchor in Wells Harbor. The proposed rule... principally for use by yachts and other recreational craft. Temporary floats or buoys for marking anchors or...

  19. Mini-implants for orthodontic anchorage

    NARCIS (Netherlands)

    Reynders, Reint Meursinge; Ladu, Luisa

    2017-01-01

    Data sourcesPubmed, Embase, Cochrane Central Register of Controlled Trials and the Web of Science databases. Hand searches of the journals European Journal of Orthodontics, Journal of Orthodontics, Journal of Clinical Orthodontics, Seminars in Orthodontics, American Journal of Orthodontics &

  20. Measuring the democratic anchorage of governance networks

    DEFF Research Database (Denmark)

    Fotel, Trine; Sørensen, Eva; Torfing, Jacob

    There has been a growing debate about the democratic problems and potentials of governance networks among political scientists and public managers. While some claim that governance networks tend to undermine democracy, others argue that they have the potential to improve and strengthen democracy...... problems and merits of governance networks. This assumption is highly questionable, and prevents a more nuanced assessment of the democratic performance of governance networks. As such, it diverts the focus of attention away from the fact that governance networks may be democratic in some respects...

  1. Avaliação in vitro da resistência à flexão de um protótipo de mini-implante desenvolvido para ancoragem do aparelho de Herbst In vitro flexural strength evaluation of a mini-implant prototype designed for Herbst appliance anchorage

    Directory of Open Access Journals (Sweden)

    Klaus Barretto-Lopes

    2010-08-01

    Full Text Available OBJETIVO: o propósito do presente estudo é avaliar o limite de resistência à flexão de um protótipo de mini-implante desenvolvido para ancoragem do aparelho de Herbst. MÉTODOS: após a realização de um cálculo do tamanho da amostra, quatro corpos de prova contendo os protótipos de mini-implantes foram submetidos a uma força de flexão por engastamento simples, utilizando-se uma máquina universal de ensaios mecânicos, sendo calculado o limite de resistência à força de flexão. RESULTADOS: após os ensaios mecânicos, os novos mini-implantes apresentaram o limite de resistência à força de flexão de 98,2kgf, que foi o menor valor encontrado. CONCLUSÃO: os protótipos de mini-implantes desenvolvidos para ancoragem do aparelho de Herbst foram capazes de suportar forças de flexão maiores do que as forças de mordida descritas na literatura.AIM: The purpose of this study was to evaluate the limit of flexural strength of a mini-implant prototype designed for Herbst appliance anchorage. METHODS: After sample size calculation, four specimens with the new mini-implant were submitted to a single cantilever flexure test using a universal testing machine. The limit of flexural force strength was calculated. RESULTS: The mini-implant prototype showed a limit of flexural force strength of 98.2 kgf (982 N, that was the lowest value found. CONCLUSION: The mini-implant prototype designed for Herbst appliance anchorage can withstand flexural forces higher than the maximum human bite forces reported in the literature.

  2. 76 FR 78185 - Anchorage Regulations: Subpart A-Special Anchorage Regulations, Newport Bay Harbor, CA

    Science.gov (United States)

    2011-12-16

    ..., Governmental Actions and Interference with Constitutionally Protected Property Rights. Civil Justice Reform... alignment as permitted by the harbor master. Sec. 110.212 [Removed and Reserved] 3. Remove and reserve Sec...

  3. Factors affecting the clinical success of orthodontic anchorage: Experience with 266 temporary anchorage devices

    Directory of Open Access Journals (Sweden)

    Tai-Ting Lai

    2014-03-01

    Conclusion: In order to improve the success rates, local inflammation should be monitored and controlled, force application should be 4 weeks after insertion, and the location for placement of TADs should be good quality bone with keratinized mucosa.

  4. 78 FR 67300 - Anchorage Regulations: Pacific Ocean at San Nicolas Island, Calif.; Restricted Anchorage Areas

    Science.gov (United States)

    2013-11-12

    ... out of danger zones from missile launch or hazard patterns. However, restricted areas are currently... Department of Homeland Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide...

  5. 77 FR 45988 - Anchorage Regulations; Great Chebeague Island, ME

    Science.gov (United States)

    2012-08-02

    ... Budget has not reviewed it under that Order. We expect minimal additional cost impacts on fishing or... might be small entities: The owners or operators of recreational and small fishing vessels intending to... area is principally for use by recreational craft. Temporary floats or buoys for marking anchors or...

  6. 77 FR 22489 - Special Anchorage Regulations, Newport Bay Harbor, CA

    Science.gov (United States)

    2012-04-16

    ... implications under Executive Order 12630, Governmental Actions and Interference with Constitutionally Protected..., may provide for fore and aft moorings for recreational and small craft of such size and alignment as...

  7. Tissue reaction surrounding miniscrews for orthodontic anchorage: An animal experiment

    Directory of Open Access Journals (Sweden)

    Stephanie Shih-Hsuan Chen

    2012-03-01

    Results and conclusions: (1 Tissue surrounding roots damaged by a miniscrew showed a significant inflammatory response. (2 Root resorption was occasionally observed after 3 weeks following insertion of a miniscrew even if the miniscrew was not in direct contact with the root. (3 Root repair was noted with a cementoblast lining along the resorption surface at as early as 3 weeks after miniscrew insertion. Alveolar bone filled in the lesion when the root damage was large so that the contour of the alveolar bone followed that of the damaged root, with the width of the periodontal ligament space being maintained. (4 Stable miniscrews were mainly those which did not contact adjacent roots, and for which the surrounding tissue showed only a small inflammatory response with some extent of direct bone contact around the miniscrew. On the contrary, most of the failed miniscrews were those which had direct contact with adjacent roots, and which exhibited severe tissue inflammation and were covered by thick layers of soft tissue. Failure was detected 3 weeks after insertion. Surprisingly, the epithelial lining surrounding the miniscrews might not have spontaneously resolved 6 weeks after screw removal. Persistent infection in the sinus tract was noted, and this would require attention.

  8. Role of MYC in Anchorage-Dependent Growth

    National Research Council Canada - National Science Library

    Benaud, Christelle

    2000-01-01

    .... We have shown, here using a human mammary epithelial model, that the expression of the early growth control gene, c-Myc, is directly regulated by cell adhesion through a 1 integrin-dependent pathway...

  9. DCS Survey Submission for Municipality of Anchorage, AK PMR

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Survey data includes spatial datasets and data tables necessary to digitally represent data collected in the survey phase of the study. (Source: FEMA Guidelines and...

  10. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, MUNICIPALITY OF ANCHORAGE, ALASKA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  11. "Dinosaurs." Kindergarten. Anchorage School District Elementary Science Program.

    Science.gov (United States)

    Herminghaus, Trisha, Ed.

    This unit contains 15 lessons on dinosaurs for kindergarten children. It provides a materials list, supplementary materials list, use of process skill terminology, unit objectives, vocabulary, six major dinosaurs, and background information. Lessons are: (1) "Webbing"; (2) "Introduction to the Big Six"; (3) "Paleontology…

  12. Mini-implants for direct or indirect orthodontic anchorage

    NARCIS (Netherlands)

    Ren, Yijin

    2009-01-01

    DATA SOURCES: Studies were sourced using Medline, the Cochrane Library and hand searches of key orthodontic journals. STUDY SELECTION: The review was restricted to peer-review articles (randomised controlled studies, prospective clinical studies and retrospective clinical studies) dealing with

  13. Analysis of Seat Belt Anchorage Strength for Vehicles

    Science.gov (United States)

    Shi, Peicheng; Xu, Zengwei

    2018-01-01

    In order to improve the efficiency of seat design and enhance the safety of vehicle seats, it is necessary to carry out CAE analysis on seat safety before making physical tests. In this paper, the finite element analysis theory and HyperWorks finite element analysis software are applied in the pretreatment of vehicle seats, seat belts, as well as the upper limbs and buttocks of dummies. The loading time and load of the seat are set according to GB 14167-2013 of the People’s Republic of China, and CAE calculation is carried out based on LSDYNA software, obtaining the stress-strain nephogram of the corresponding vehicle seats. An improved scheme is proposed base on the analysis results, and CAE analysis is carried out on the improved seats again. The results of the analysis fully meet the national standard GB 14167-2013 and material strength requirements, which are of important guiding significance in reducing the development costs, shortening the development cycle and improving the passing rate of physical test.

  14. 49 CFR 571.225 - Standard No. 225; Child restraint anchorage systems.

    Science.gov (United States)

    2010-10-01

    .... A steel cable is connected to the X point through which the test force is applied. S8.1Apply the... tightened to a tension of not less than 53.5 N and not more than 67 N on the webbing portion of the belt.... While maintaining the force, tighten the vehicle seat belt to a tension of not less than 53.5 N and not...

  15. Damage to the root after tooth movement towards a temporary anchorage device: An animal pilot study

    Directory of Open Access Journals (Sweden)

    Cheng-Tsung Huang

    2012-06-01

    Conclusions: A root moving towards a screw during OTM leads to crater-like damage. When time was allowed for healing, a trace of labeled cementum was found to have repaired the root surface, although a large portion of the concavity was filled in with alveolar bone, and the periodontal ligament space remained constant. A root moving against a screw produced excessive tipping. To avoid deviation from the predicted biomechanics and damage to the root, extra caution should be used to ensure the best benefits for patients when TADs are used interdentally for distalization of the dentition during orthodontic treatment.

  16. Denmark: criminal law as an anchorage point for pro-active anti-terrorism legislation

    DEFF Research Database (Denmark)

    Vestergaard, Jørn

    2012-01-01

    The article focuses on the compatibility of criminal law anti-terrorism legislation in Danish law with basic principles regarding the rule of law and due process. The so-called anti-terror-packages of 2002 and 2006 involve a set of rather uncertain and wide-reaching provisions fundamentally...... challenging the principle of legality and substantially widening of the scope of criminal law. These provisions criminalize various activities more or less remote from actual or attempted terrorist acts and participation in such activities, too. The legislature has even over-implemented vari-ous legal......, the challenges regarding rule of law and due process also relate to secondary legislation in fields like law enforcement, criminal procedure, intelligence, public law, treatment of foreigners, etc....

  17. Anchorage of titanium implants with different surface characteristics: an experimental study in rabbits

    DEFF Research Database (Denmark)

    Gotfredsen, K; Berglundh, T; Lindhe, J

    2000-01-01

    ) TiO2-blasted with particles of grain size 10 to 53 microns; (3) TiO2-blasted, grain size 63 to 90 microns; (4) TiO2-blasted, grain size 90 to 125 microns; (5) titanium plasma-sprayed (TPS). The surface topography was determined by the use of an optical instrument. Twelve rabbits, divided into two...... groups, had a total of 120 implants inserted in the tibiae. One implant from each of the five surface categories was placed within the left tibia of each rabbit. By a second operation, implants were installed in the right tibia, after 2 weeks in group A and after 3 weeks in group B. Fluorochrome labeling...

  18. INFLUENCE OF PIT WALL ANCHORAGE ONTO ADDITIONAL DEFORMATIONS OF EXISTING BUILDINGS

    Directory of Open Access Journals (Sweden)

    Kubetskiy Valeriy Leonidovich

    2012-07-01

    Assessment of additional projected deformations of buildings located in close proximity to pits is exemplified by the specific structure of the pit support system that has active PIT [1] anchors. The authors also consider the influence produced by the structure of anchors onto the two buildings located within the area of influence of the excavation works and protected by the anchors installed underneath the foundations of the two adjacent buildings.

  19. Poetry Education Research as an Anchorage of Thought: Using Poetry as Interview Stimulus Material

    Science.gov (United States)

    Xerri, Daniel

    2017-01-01

    Interviews in qualitative research may sometimes employ stimulus material as a means of eliciting richer data. However, scant consideration has been given to the use of poetry for this purpose, especially within the field of poetry education research. This article seeks to address the gap in the literature by illustrating how the use of poetry as…

  20. 2016 NOAA NGS Ortho-rectified Color Mosaic of Anchorage, Alaska

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains ortho-rectified mosaic tiles, created as a product from the NOAA Integrated Ocean and Coastal Mapping (IOCM) initiative. The source imagery...

  1. Elmendorf AFB, Anchorage, Alaska. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

    Science.gov (United States)

    1979-09-17

    40.7 4 .7 ’ nIF , ’,1 5!.3 5 .,o 51.,l 5 1 1.* L,3 51.3 I 10000 5U.8 51.5 52.2 )2.2 52.7 52.1 5,.7 52.9 5 .9 53.2 53.9 54.1 54. 1 54,2 54.2 54.2 I 900_...h 2 US, ETAC CEILING VERSUS V I T AIR WEATHER SERVICE/MAC _2k ,. ELME9OURF AF5 A ASKAlANC.IURAGL2 C6 -75 srp PERCENTAGE FREQUENCY OF OCCURRENCE 1Q1...9 5. 4 9 5. 4 1 9 5, 4 9 5 4 1 9 5 : l 9 , 4I 9 5 . 4 95 4 150 >- :o4,4 95: 1 5 9 9: 6 1 6 1 C6 96 02 9 021 96.2 1). ,) 96 7 9o cf. 2 )6 6 . ) 2

  2. Remedial Investigation/Feasibility Study, Operable Unit 5, Elmendorf AFB, Anchorage, Alaska. Volume 1. Text

    Science.gov (United States)

    1994-03-04

    hPow _ _ _ _ _ _ _~~~... ...._ .__ _4_ _ _ _ 006 036 Q0 4p 4I own" sm Mm~A U 5KI Mums 2-76 swaom jercduru rquired of CL? vei iv analysi. Th labors ...9 • •9 UST OF TAULIM Pbp 3-1 Clima Da for badrf AFB ............................. 3-2 3-2 Wind Dretim by Pe ie xar ums da A ..................... 3

  3. Anchorage of γ-Al2O3 nanoparticles on nitrogen-doped multiwalled carbon nanotubes

    International Nuclear Information System (INIS)

    Rodríguez-Pulido, A.; Martínez-Gutiérrez, H.; Calderon-Polania, G.A.; Lozano, M.A. Gonzalez; Cullen, D.A.; Terrones, H.; Smith, D.J.; Terrones, M.

    2016-01-01

    Nitrogen-doped multiwalled carbon nanotubes (CNx-MWNTs) have been decorated with γ-Al 2 O 3 nanoparticles by a novel method. This process involved a wet chemical approach in conjunction with thermal treatment. During the particle anchoring process, individual CNx-MWNT nanotubes agglomerated into bundles, resulting in arrays of aligned CNx-MWNT coated with γ-Al 2 O 3 . Extensive characterization of the resulting γ-Al 2 O 3 /CNx-MWNT bundles was performed using a range of electron microscopy imaging and microanalytical techniques. A possible mechanism explaining the nanobundle alignment is described, and possible applications of these materials for the fabrication of ceramic composites using CNx-MWNTs are briefly discussed.

  4. The root anchorage ability of Salix alba var. tristis using a pull-out test

    African Journals Online (AJOL)

    Our results showed that, the plant had a satisfactory root development after 4 years, and the pull-out resistive force had the strongest correlations with the morphological parameters of plant, such as height (R2 = 0.79, P < 0.001) and diameter at shoot base (R2 = 0.69, P < 0.001). Key words: Salix alba var. tristis, uprooting ...

  5. DCS Floodplain Mapping Submition for Furrow Creek and Girdwood (Anchorage, AK)

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  6. History of urethral catheters and their balloons: drainage, anchorage, dilation, and hemostasis.

    Science.gov (United States)

    Marino, R A; Mooppan, U M; Kim, H

    1993-04-01

    Male urethral catheterization, as practiced in early Greece, was made possible by a sound knowledge of anatomy. It has been preserved by written tradition and advanced by the development of new materials. Balloon dilation, conceived and practiced more than 160 years ago by urologists, has undergone a similar cycle. Some useful ideas, once conceived, have been forgotten and have surfaced again, decades, sometimes centuries, later as new inventions.

  7. Method for predicting selective uprooting by mechanical weeders from plant anchorage forces

    NARCIS (Netherlands)

    Kurstjens, D.A.G.; Kropff, M.J.; Perdok, U.D.

    2004-01-01

    Reliable mechanical weed control requires knowledge of the achievable levels of weed control and crop damage when using certain implements in specific conditions. Quantitative methods that use weed, crop, soil, and cultivator characteristics to predict weed control and crop damage need to be

  8. Skeletal Anchorage using Mini-implants in the Maxillary Tuberosity Region

    Directory of Open Access Journals (Sweden)

    Sundaram Venkateswaran

    2013-01-01

    The case reports discussed in the article demonstrates the ability of mini-implants when placed in the maxillary tuberosity for en masse distalization of the entire maxillary dentition, its advantages and biomechanics.

  9. Mini-implants for Orthodontic Anchorage: Surface Analysis after Redrilling and Sterilization - An in vitro Study.

    Science.gov (United States)

    Gross, J M; Nascimento, G G; Araújo, V C; Bönecker, Mjs; Furuse, C

    2016-04-01

    This study aimed to investigate, in vitro, possible alterations on mini-implants surface after retrieval and if the cleaning process and sterilization can predispose damages. Two commercial mini-implants were tested for deformations after drilling and removing in artificial bone four times. Samples were analyzed by scanning electron microscopy, and surface alterations verified through thread and pitches deformation. To alterations caused by insertion/removal and the cleaning process and sterilization were verified in different procedures: Insertions and sterilization, only insertions, and only sterilization. Photomicrographs were analyzed in order to compare the surface characteristics. Head deformation was verified qualitatively. For a quantitative analysis, distances between threads were measured across the active part of the mini-implants. No deformation was observed in both groups. The cleaning and sterilization processes did not provoke alteration in both groups. Nevertheless, the presence of synthetic bone was noted in some samples. The mean distances between implant threads were similar after all steps in all regions in both groups. The results suggest that the tested mini-implants can be retrieved without damage of its surface after four cycles of insertion, removal, and sterilization. Orthodontic mini-implant, Redrilling, Sterilization. Mini-implants can be retrieved without damage to its surface after four cycles of insertion, removal, and sterilization in the same patient without representing a biological concern.

  10. Survival of palatal miniscrews used for orthodontic appliance anchorage: a retrospective cohort study

    NARCIS (Netherlands)

    Karagkiolidou, A.; Ludwig, B.; Pazera, P.; Gkantidis, N.; Pandis, N.; Katsaros, C.

    2013-01-01

    INTRODUCTION: The purpose of this study was to examine the overall success of miniscrews inserted in the paramedian palatal region for support of various appliances during orthodontic treatment. METHODS: The patients received 1 or 2 miniscrews in the paramedian anterior palate of 8.0-mm length and

  11. Survival of palatal miniscrews used for orthodontic appliance anchorage: a retrospective cohort study.

    Science.gov (United States)

    Karagkiolidou, Angeliki; Ludwig, Björn; Pazera, Pawel; Gkantidis, Nikolaos; Pandis, Nikolaos; Katsaros, Christos

    2013-06-01

    The purpose of this study was to examine the overall success of miniscrews inserted in the paramedian palatal region for support of various appliances during orthodontic treatment. The patients received 1 or 2 miniscrews in the paramedian anterior palate of 8.0-mm length and 1.6-mm diameter placed during orthodontic treatment by the same experienced orthodontist. In total, 196 patients (121 girls, 75 boys; median age, 11.7; interquartile range, 3.7) who received 384 miniscrews were evaluated. Two hundred four miniscrews were used with rapid palatal expansion appliances, 136 with appliances for distalization of posterior teeth, and 44 with other appliances, such as transpalatal arches for tooth stabilization. The overall survival of the miniscrews was excellent (97.9%) in the cases examined. Cox regression analysis showed no difference in the overall survival rates of miniscrews loaded with different appliances for sex (hazard ratio, 0.95; 95% confidence interval, 0.71-1.27; P = 0.73) after adjusting for appliance and age. This study shows that miniscrews placed in the paramedian anterior palate for supporting various orthodontic appliances have excellent survival. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  12. Study on effective anchorage length of anchor cable based on Gauss's function

    Science.gov (United States)

    Ren, Feng; WuShuai; Liu, Yan; Liu, Jun-yan

    2017-11-01

    In the current relevant codes and technical standards, the design of anchor cables (bars) is based on the assumption that the shear stress is distributed uniformly along the anchor segment. However, according to this assumption, the super-deep pit need a large uplift bearing capacity, which will lead to the long anchor segment and has great hidden danger in the actual engineering design. Therefore, this paper, based on the previous derived shear stress function between τ and the anchor length, we get a research suitable model-Gauss curve distribution model through the analysis of saturated clay drawing data, and strata anchor shear stress distribution is more suitable for the Gauss function model in saturated clay; at the same time, through the FLAC numerical simulation of Jinan Government Affairs Center project, we obtained the optimal anchor effective anchor length is about 10~12m, the foundation pit anchor is optimized.

  13. Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation

    OpenAIRE

    Hori, Akiko; Ikebe, Chiho; Tada, Masazumi; Toda, Takashi

    2014-01-01

    Anchoring microtubules to the centrosome is critical for cell geometry and polarity, yet the molecular mechanism remains unknown. Here we show that the conserved human Msd1/SSX2IP is required for microtubule anchoring. hMsd1/SSX2IP is delivered to the centrosome in a centriolar satellite-dependent manner and binds the microtubule-nucleator ?-tubulin complex. hMsd1/SSX2IP depletion leads to disorganised interphase microtubules and misoriented mitotic spindles with reduced length and intensity....

  14. Ancient anchorage systems in India with reference to the Gujarat coast

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh; Tripati, S.

    the different phases of history. Mesopotamian texts vividly described the existence of docks in the 3 rd millennium BC. The king Sargon the Great was quoted to boast that boats of Dilmun, Magan, and Meluhha lay anchored at the docks of Agade, which...

  15. Ancient technology of jetties and anchorage system along the Saurastra coast, India

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh

    the manufacturing stage and not during the anchoring processes. A composite anchor made of limestone is another noteworthy find from the site. The presence of a few unfinished anchors at Gogha and Hathab, which lie submerged in 5–7 m. water during high tide... (1966) Excavations at Dwarka, Pune: Deccan College Postgraduate and Research Institute. Bhan, K.K. (2006) ‘Towards an Understanding of Medieval Glazed Pottery Manufacture from Lakshkarshah, Khambhat, Gujarat’, Man and Environment, vol. XXXI, no. 2, pp...

  16. H10232: NOS Hydrographic Survey , Tampa Bay Anchorage Area, Florida, 1986-08-28

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  17. Membrane anchorage brings about fusogenic properties in a short synthetic peptide

    NARCIS (Netherlands)

    Pecheur, EI; Hoekstra, D; SainteMarie, J; Maurin, L; Bienvenue, A; Philippot, [No Value

    1997-01-01

    The fusogenic properties of an amphipathic net-negative peptide (wae 11), consisting of 11 amino acid residues, were studied. We demonstrate that, whereas the free peptide displays no significant fusion activity, membrane fusion is strongly promoted when the peptide is anchored to a liposomal

  18. 78 FR 51061 - Special Anchorage Areas; Port of New York, NY

    Science.gov (United States)

    2013-08-20

    ... comments stated that the Municipal Harbor Master only has the authority to manage the 172 moorings within... transiting the area. Additionally, floating docks installed adjacent to the proposed northern special...

  19. 76 FR 21633 - Disestablishing Special Anchorage Area 2; Ashley River, Charleston, SC

    Science.gov (United States)

    2011-04-18

    ... management systems practices) that are developed or adopted by voluntary consensus standards bodies. This... accommodate an expansion of the Ripley Light Yacht Club. DATES: This rule is effective July 18, 2011... ``Search.'' This material is also available for inspection or copying at the Docket Management Facility (M...

  20. The root anchorage ability of Salix alba var. tristis using a pull-out test

    African Journals Online (AJOL)

    user

    2011-11-21

    Nov 21, 2011 ... Swets and Zeitlinger, Lisse. pp. 593-597. Norris JE (2005). Root reinforcement by hawthorn and oak roots on a highway cut-slope in Southern England. Plant Soil, 278: 43-53. Operstein V, Frydman S (2000). The influence of vegetation on soil strength. Ground Improv. 4: 81-89. Puri S, Singh V, Bhushan B, ...

  1. Anchorage zone design for pretensioned precast bulb-T bridge girders in Virginia.

    Science.gov (United States)

    2009-01-01

    Precast/prestressed concrete girders are commonly used in bridge construction in the United States. The application and diffusion of the prestress force in a pretensioned girder cause a vertical tension force to develop near the end of the beam. Fiel...

  2. The root anchorage ability of Salix alba var. tristis using a pull-out test

    African Journals Online (AJOL)

    user

    2011-11-21

    Nov 21, 2011 ... In the last few years, Beijing Forestry University (China) and the University of Natural Resources and applied Life. Sciences (Austria) have examined the suitabilities and capabilities of soil bioengineering techniques under the local condition of Beijing. One of the plant species used was Salix alba var. tristis.

  3. Autologous reattachment of complicated crown fractures using intra canal anchorage: Report of two cases

    OpenAIRE

    Kashetty Panchakshari Bharath; Raju Umaji Patil; Haalaswamy Vishwanath Kambalimath; Ashokan Alexander

    2015-01-01

    Crown fractures are most common form of dental trauma sustained by children and adolescents. Major portion of these crown fractures are uncomplicated. Complicated crown fractures though infrequent and account only 4-16%, is an enigma to any clinician. Autologus reattachment of the tooth fragment is a simple and conservative procedure in managing such crown fractures. The present article intends to report the successful clinical management of Autologus tooth fragment reattachment in two compli...

  4. Numerical Simulation and Experimental Validation of an Integrated Sleeve-Wedge Anchorage for CFRP Rods

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Smith, Scott T.; Täljsten, Björn

    2011-01-01

    The tensioning of carbon fibre-reinforced polymer (CFRP) rods for prestressed concrete applications or post-tensioning repair and strengthening has met with mixed success. This is primarily due to limitations inherent in the use of traditional wedge anchors typically used for steel tendons...

  5. H08727: NOS Hydrographic Survey , Fire Island to Anchorage, Alaska, 1963-06-18

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  6. 49 CFR 571.210 - Standard No. 210; Seat belt assembly anchorages.

    Science.gov (United States)

    2010-10-01

    ... bolt holes or the centroid of any other means of attachment to the structure specified in 4.1.3.1... are either: (a) For designated seating positions that are common to the same occupant seat and that... common to the same occupant seat, but that face in the same direction, if the vertical centerline of the...

  7. Family businesses and their anchorages in Central European society in the 19th century

    Czech Academy of Sciences Publication Activity Database

    Hlavačka, Milan

    2016-01-01

    Roč. 24, č. 2 (2016), s. 1-22 ISSN 1210-6860 R&D Projects: GA ČR(CZ) GA14-19640S Institutional support: RVO:67985963 Keywords : Family Business * Central Europe * 19th century Subject RIV: AB - History

  8. In vitro validation of a novel mechanical model for testing the anchorage capacity of pedicle screws using physiological load application.

    Science.gov (United States)

    Liebsch, Christian; Zimmermann, Julia; Graf, Nicolas; Schilling, Christoph; Wilke, Hans-Joachim; Kienle, Annette

    2018-01-01

    Biomechanical in vitro tests analysing screw loosening often include high standard deviations caused by high variabilities in bone mineral density and pedicle geometry, whereas standardized mechanical models made of PU foam often do not integrate anatomical or physiological boundary conditions. The purpose of this study was to develop a most realistic mechanical model for the standardized and reproducible testing of pedicle screws regarding the resistance against screw loosening and the holding force as well as to validate this model by in vitro experiments. The novel mechanical testing model represents all anatomical structures of a human vertebra and is consisting of PU foam to simulate cancellous bone, as well as a novel pedicle model made of short carbon fibre filled epoxy. Six monoaxial cannulated pedicle screws (Ø6.5 × 45mm) were tested using the mechanical testing model as well as human vertebra specimens by applying complex physiological cyclic loading (shear, tension, and bending; 5Hz testing frequency; sinusoidal pulsating forces) in a dynamic materials testing machine with stepwise increasing load after each 50.000 cycles (100.0N shear force + 20.0N per step, 51.0N tension force + 10.2N per step, 4.2Nm bending moment + 0.8Nm per step) until screw loosening was detected. The pedicle screw head was fixed on a firmly clamped rod while the load was applied in the vertebral body. For the in vitro experiments, six human lumbar vertebrae (L1-3, BMD 75.4 ± 4.0mg/cc HA, pedicle width 9.8 ± 0.6mm) were tested after implanting pedicle screws under X-ray control. Relative motions of pedicle screw, specimen fixture, and rod fixture were detected using an optical motion tracking system. Translational motions of the mechanical testing model experiments in the point of load introduction (0.9-2.2mm at 240N shear force) were reproducible within the variation range of the in vitro experiments (0.6-3.5mm at 240N shear force). Screw loosening occurred continuously in each case between 140N and 280N, while abrupt failures of the specimen were observed only in vitro. In the mechanical testing model, no translational motion was detected in the screw entry point, while in vitro, translational motions of up to 2.5mm in inferior direction were found, leading to a slight shift of the centre of rotation towards the screw tip. Translational motions of the screw tip of about 5mm in superior direction were observed both in vitro and in the mechanical testing model, while they were continuous in the mechanical testing model and rapidly increasing after screw loosening initiation in vitro. The overall pedicle screw loosening characteristics were qualitatively and quantitatively similar between the mechanical testing model and the human vertebral specimens as long as there was no translation of the screw at the screw entrance point. Therefore, the novel mechanical testing model represents a promising method for the standardized testing of pedicle screws regarding screw loosening for cases where the screw rotates around a point close to the screw entry point. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. A short-stem hip implant with metaphyseal anchorage in patients with developmental dysplasia of the hip.

    Science.gov (United States)

    Budde, Stefan; Floerkemeier, Thilo; Thorey, Fritz; Ezechieli, Marco; Claassen, Leif; Ettinger, Max; Bredow, Jan; Windhagen, Henning; Lewinski, Gabriela von

    2016-03-18

    Short-stem implants are routinely used for total hip arthroplasty in younger patients that are more likely to have secondary osteoarthritis than older patients. To investigate the applicability of short-stem hip implants for secondary osteoarthritis due to developmental dysplasia of the hip. This study analyzed the clinical and radiological results of patients with developmental dysplasia of the hip (DDH, 58 hips) and compared them to those of patients with primary osteoarthritis (POA, 59 hips) treated with the metaphyseal total hip arthroplasty (Metha®) short stem with metaphyseal fixation. The mean clinical and radiological follow-up periods were 2.9 ± 1.1 years and 3.8 ± 1.9 years, respectively. The mean Harris Hip Score (HHS) significantly increased in both groups over this period (p< 0.0001). The caput-collum-diaphysis (CCD) angle was significantly lower in the POA group prior to surgery and significantly increased in the POA and and decreased in DDH groups, respectively. The preoperative femoral offset was lower in the DDH group and increased significantly after surgery. The Metha® short stem in patients with DDH allows good reconstruction of joint biomechanics with a good clinical outcome.

  10. F00437B: NOS Hydrographic Survey , Delaware Bay, Delaware, Vicinity of Big Stone Anchorage Area, 1997-11-17

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  11. Chin remodeling in a patient with bimaxillary protrusion and open bite by using mini-implants for temporary anchorage.

    Science.gov (United States)

    Jiang, Chunmiao; Liu, Yinghong; Cheng, Qian; He, Wei; Fang, Shanbao; Lan, Tingting; Wang, Jun

    2018-03-01

    Patients with bimaxillary protrusion may have an unattractive profile with a retruded chin contour. Correction of the severely protrusive anterior alveolar bone and teeth combined with a moderate open bite without orthognathic surgery can be challenging. This case report describes the orthodontic treatment of a woman with severe bimaxillary protrusion and a moderate open bite. Excellent chin morphology and facial appearance were obtained with the extraction of 4 first premolars and 4 third molars, and total distalization of both arches with 4 mini-implants, one in each quadrant between the second premolar and the first molar. The total treatment time was 30 months. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  12. IMPROVED TISSUE INGROWTH AND ANCHORAGE OF EXPANDED POLYTETRAFLUOROETHYLENE BY PERFORATION - AN EXPERIMENTAL-STUDY IN THE RAT

    NARCIS (Netherlands)

    SIMMERMACHER, RKJ; VANDERLEI, B; SCHAKENRAAD, JM; BLEICHRODT, RP

    Although an expanded polytetrafluoroethylene patch is a suitable synthetic material to repair large abdominal wall defects, lack of tissue ingrowth into the patch may give rise to herniation at the fascia-patch interface. This study was undertaken to determine whether perforations and/or ethanol

  13. 33 CFR 165.110 - Safety and Security Zone; Liquefied Natural Gas Carrier Transits and Anchorage Operations, Boston...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety and Security Zone... Limited Access Areas First Coast Guard District § 165.110 Safety and Security Zone; Liquefied Natural Gas.... The following areas are safety and security zones: (1) Vessels underway. All navigable waters of the...

  14. Water. An Environmental Learning Experience for Use at the Second Grade Primary Level. Anchorage School District Elementary Science Program.

    Science.gov (United States)

    Anchorage School District, AK.

    This resource book introduces second-grade children to the importance of water and the environment. The lessons and concepts covered in this unit are designed to develop an awareness of the importance of water in our lives, an awareness of some of the things water can do, and an awareness of our responsibility to help protect and conserve our…

  15. 77 FR 66942 - Anchorages; Lower Mississippi River, Above Head of Passes, Convent, LA and Point Pleasant, LA

    Science.gov (United States)

    2012-11-08

    ... by docket number USCG- 2012-0103 using any one of the following methods: (1) Federal eRulemaking... Meeting We do not now plan to hold a public meeting. But you may submit a request for one using one of the... locations, thus allowing greater vessel volume in order to meet the growing economic needs of facilities...

  16. Inhibition of Curcumin on ZAKα Activity Resultant in Apoptosis and Anchorage-Independent Growth in Cancer Cells.

    Science.gov (United States)

    Lee, Jin-Sun; Wang, Tsu-Shing; Lin, Ming Cheng; Lin, Wei-Wen; Yang, Jaw-Ji

    2017-10-31

    Curcumin, a popular yellow pigment of the dietary spice turmeric, has been reported to inhibit cell growth and to induce apoptosis in a wide variety of cancer cells. Although numerous studies have investigated anticancer effects of curcumin, the precise molecular mechanism of action remains unidentified. Whereas curcumin mediates cell survival and apoptosis through mitogen-activated protein kinase (MAPK) and nuclear factor-kappa B (NF-κB) signaling cascades, its impact on the upstream regulation of MAPK is unclear. The leucine-zipper and sterile-α motif kinase alpha (ZAKα), a mitogen-activated protein kinase kinase kinase (MAP3K), activates the c-Jun N-terminal kinase (JNK) and NF-κB pathway. This paper investigated the prospective involvement of ZAKα in curcumin-induced effects on cancer cells. Our results suggest that the antitumor activity of curcumin is mediated via a mechanism involving inhibition of ZAKα activity.

  17. 76 FR 36157 - In the Matter of Alaska Industrial X-Ray, Inc., Anchorage, AK; Confirmatory Order Modifying...

    Science.gov (United States)

    2011-06-21

    ... professional mediator, arranged through Cornell University's Institute on Conflict Resolution. ADR is a process... Confirmatory Order is the result of an agreement reached during an alternative dispute resolution (ADR... following: Pursuant to the Nuclear Regulatory Commission Office of Enforcement's Alternative Dispute...

  18. Remedial Investigation/Feasibility Study, Operable Unit 5, Elmendorf AFB, Anchorage, Alaska. Volume 2. Text and Appendices A - J

    Science.gov (United States)

    1994-03-04

    Toxicol. 29:392-399. Hiardin. B. D., et al. 1981. Testing of Selected Workplace Chemicals for Teratogenic Potential. Scand. J. Work Environ. Health...blanks contained concentrations of barium, calcium, iron, selenium, sodium, thallium , or zinc below the contract required detection limit (CRDL...37A. Thallium was detected in two samples analyzed. Thallium was only detected in the soluble fraction of 5MW1 5-10 and was not detected in the soluble

  19. Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

    Directory of Open Access Journals (Sweden)

    Martin F Dietrich

    2010-04-01

    Full Text Available The low-density lipoprotein (LDL receptor gene family is a highly conserved group of membrane receptors with diverse functions in developmental processes, lipoprotein trafficking, and cell signaling. The low-density lipoprotein (LDL receptor-related protein 1b (LRP1B was reported to be deleted in several types of human malignancies, including non-small cell lung cancer. Our group has previously reported that a distal extracellular truncation of murine Lrp1b that is predicted to secrete the entire intact extracellular domain (ECD is fully viable with no apparent phenotype.Here, we have used a gene targeting approach to create two mouse lines carrying internally rearranged exons of Lrp1b that are predicted to truncate the protein closer to the N-terminus and to prevent normal trafficking through the secretary pathway. Both mutations result in early embryonic lethality, but, as expected from the restricted expression pattern of LRP1b in vivo, loss of Lrp1b does not cause cellular lethality as homozygous Lrp1b-deficient blastocysts can be propagated normally in culture. This is similar to findings for another LDL receptor family member, Lrp4. We provide in vitro evidence that Lrp4 undergoes regulated intramembraneous processing through metalloproteases and gamma-secretase cleavage. We further demonstrate negative regulation of the Wnt signaling pathway by the soluble extracellular domain.Our results underline a crucial role for Lrp1b in development. The expression in mice of truncated alleles of Lrp1b and Lrp4 with deletions of the transmembrane and intracellular domains leads to release of the extracellular domain into the extracellular space, which is sufficient to confer viability. In contrast, null mutations are embryonically (Lrp1b or perinatally (Lrp4 lethal. These findings suggest that the extracellular domains of both proteins may function as a scavenger for signaling ligands or signal modulators in the extracellular space, thereby preserving signaling thresholds that are critical for embryonic development, as well as for the clear, but poorly understood role of LRP1b in cancer.

  20. Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage

    DEFF Research Database (Denmark)

    Lydolph, Magnus C; Morgan-Fisher, Marie; Høye, Anette M

    2009-01-01

    Cell surface integrins are the primary receptors for cell migration on extracellular matrix, and exist in several activation states regulated in part by ectodomain conformation. The alpha9 integrin subunit, which pairs only with beta1, has specific roles in the immune system and may regulate cell...... migration. Melanoma cells express abundant alpha9beta1 integrin, and its role in cell migration was assessed. Ligands derived from Tenascin-C and ADAM12 supported alpha9beta1 integrin-mediated cell attachment and GTP-Rac dependent migration, but not focal adhesion formation. Manganese ions induced alpha9......beta1 integrin- and Rho kinase-dependent focal adhesion and stress fibre formation, suggesting that the activation status of alpha9beta1 integrin was altered. The effect of manganese ions in promoting focal adhesion formation was reproduced by beta1 integrin activating antibody. The alpha9beta1...

  1. A novel synthetic peptide polymer with cyclic RGD motifs supports serum-free attachment of anchorage-dependent cells.

    Science.gov (United States)

    Markó, K; Ligeti, M; Mezo, G; Mihala, N; Kutnyánszky, E; Kiss, E; Hudecz, F; Madarász, E

    2008-09-01

    Cell adhesivity is a basic biological principle, which provides mechanisms for construction of multicellular organisms, tissue genesis, migration and individual cell survival. In vivo, the cell adhesive environment is provided by extracellular matrix molecules, neighboring cell surfaces and soluble factors delivered either by tissue cells or by blood circulation. The exact molecular composition of the microenvironment of a cell is not properly understood. The nondefined molecular composition of "native" adhesive components hinders their application when defined culture conditions are necessary, as, for an example, growing human cells for further clinical application. Applying large, substrate-coating molecules as backbones for carrying specific adhesive peptide motifs provides a relatively cheap, reproducible, and chemically defined group of synthetic adhesion molecules. Here, we report on the design, synthesis, and testing of a novel cyclic RGD-containing coating material, which promotes initial attachment, spreading, survival, and proliferation of a number of different cell types. The potent adhesive polypeptide-brush, composed of poly[Lys(DL-Ala(m))] branched chain polypeptide (AK) and multiple copies of cyclic(arginyl-glycyl-aspartyl-D-phenylalanyl-cysteine) pentapeptide prevents anoikis and supports cell attachment in the absence of serum or other biological additives. The defined conditions for cell maintenance make this material a promising candidate for coating artificial cell substrates even for therapeutic applications.

  2. Proceedings of the 79th Meeting of the Coastal Engineering Research Board, 6-10 June 2005 (Anchorage, AK)

    Science.gov (United States)

    2006-09-29

    sponge spicules , sea urchin spines, bryozoan skeletons, and sea shell fragments. The beach sand is produced through mechanical abrasion of its...ecosystems. The goals of the national and the Alaska systems are to: • Improve the safety and efficiency of marine operations; • More effectively...Reduce public health risks; • More effectively protect and restore healthy coastal marine ecosystems; and • Enable the sustained use of marine

  3. Finite Element Analysis of Stress and Strain Distribution in the Bone around the Implants used for Orthodontic Anchorage

    Directory of Open Access Journals (Sweden)

    P S Vijayalakshmi

    2012-01-01

    Full Text Available Biomechanical influences on bone structure play an important role in the longevity of bone around an implant. The quantity and direction of applied force influence the implant and cause deformation of the bone. FEA was used to analyze the changes in the bone on loading the implant with orthodontic force in oblique and vertical directions and orthopedic force. The Mini-implants used in the present study efficiently resisted the oblique loading. But their use, for the purpose of orthopedic loading is questionable. FE models showed the area with the highest stress and strain to be around the neck of the implant and the surrounding bone at the cervical margin.

  4. Evaluating the effects of consolidation on intrusion and retraction using temporary anchorage devices—a FEM study

    Directory of Open Access Journals (Sweden)

    Monica Namburi

    2017-01-01

    Full Text Available Abstract Background Extraction of premolars and retracting the anterior teeth using mini-implants and anterior retraction hooks became advent now a day. In such treatments, consolidation of arches is not done in regular practice. So, the present study is concentrated on effects of consolidation in two implant and three implant combinations of retraction and intrusion. Methods A three-dimensional FEM model of maxillary teeth and periodontal ligament housed in the alveolar bone with the first premolars extracted is generated with appropriate number of elements and nodes. The models were broadly divided into two groups according to the no. of implants. Mini-implants were placed bilaterally between the second premolar and molar at varying heights (7, 10, 13 mm in group I, and along with bilateral implants, an additional mid-implant is placed between the central incisors as group II. Brackets with 0.022 slot were placed on the teeth, 19 × 25 SS wire is placed in the brackets, an anterior retraction hook was placed at 9 mm height, and analysis was done to evaluate the stresses and displacement patterns in consolidation and non-consolidation models. Results The results showed that consolidation of the anterior teeth during intrusion and retraction shows various advantages such as less stresses on the bone, PDL, implant, teeth, and no labial flaring of the anterior teeth and three implant system, i.e., two bilateral implant at 10 mm and a mid-implant at 12 mm between the centrals has shown to be better than other models as bodily movement is observed. Conclusion Consolidation is better than non consolidation during enmasse retraction and intrusion.

  5. F00437: NOS Hydrographic Survey , Delaware Bay, Delaware, Vicinity of Big Stone Anchorage Area, 1997-11-17

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  6. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Mack, Hildegard I.D.; Munger, Karl, E-mail: kmunger@rics.bwh.harvard.edu

    2013-11-15

    Infection with high-risk human papillomaviruses is causally linked to cervical carcinogenesis. However, most lesions caused by high-risk HPV infections do not progress to cancer. Host cell mutations contribute to malignant progression but the molecular nature of such mutations is unknown. Based on a previous study that reported an association between liver kinase B1 (LKB1) tumor suppressor loss and poor outcome in cervical cancer, we sought to determine the molecular basis for this observation. LKB1-negative cervical and lung cancer cells were reconstituted with wild type or kinase defective LKB1 mutants and we examined the importance of LKB1 catalytic activity in known LKB1-regulated processes including inhibition of cell proliferation and elevated resistance to energy stress. Our studies revealed marked differences in the biological activities of two kinase defective LKB1 mutants in the various cell lines. Thus, our results suggest that LKB1 may be a cell-type specific tumor suppressor. - Highlights: • LKB1 is a tumor suppressor that is linked to Peutz-Jeghers syndrome. • Peutz-Jeghers syndrome patients have a high incidence of cervical cancer. • Cervical cancer is caused by HPV infections. • This study investigates LKB1 tumor suppressor activity in cervical cancer.

  7. Remedial Investigation/Feasibility Study, Operable Unit 5, Elmendorf AFB, Anchorage, Alaska. Volume 3. Appendices K - T

    Science.gov (United States)

    1994-03-04

    WagerQC MEO 6/2192 8270 04WI 51-28S 2.4D4NrTROUHIENfOL 25( (304.L WagerQC MEIO LA 6/2IM 827 04W 121-14-2 2A-DINITMOTOL(3ENE IO (3 304 WagerQC MIETHIOD...complement the use of ARARs, not to compete with ARARs. The following potential ARARs identification is divided into three categories of ARARs: 1) ambient or...sheen standards. The U.S. Environmental Protection Agency (U.S. EPA) has also developed ambient surface water quality criteria (SWQC) for the protection

  8. Treatment Effects of Occipitomental Anchorage Appliance of Maxillary Protraction Combined with Chincup Traction in Children with Class III Malocclusion

    Directory of Open Access Journals (Sweden)

    Hsiang-Chien Lin

    2007-05-01

    Conclusion: Our results suggest that the OMA orthopedic appliance can correct the mesial jaw relationship and negative incisal overjet. This appliance is effective for correcting skeletal Class III malocclusion with both midface deficiency and Mn prognathism in growing children.

  9. Fluxes of water through aquaporin 9 weaken membrane-cytoskeleton anchorage and promote formation of membrane protrusions.

    Directory of Open Access Journals (Sweden)

    Thommie Karlsson

    Full Text Available All modes of cell migration require rapid rearrangements of cell shape, allowing the cell to navigate within narrow spaces in an extracellular matrix. Thus, a highly flexible membrane and a dynamic cytoskeleton are crucial for rapid cell migration. Cytoskeleton dynamics and tension also play instrumental roles in the formation of different specialized cell membrane protrusions, viz. lamellipodia, filopodia, and membrane blebs. The flux of water through membrane-anchored water channels, known as aquaporins (AQPs has recently been implicated in the regulation of cell motility, and here we provide novel evidence for the role of AQP9 in the development of various forms of membrane protrusion. Using multiple imaging techniques and cellular models we show that: (i AQP9 induced and accumulated in filopodia, (ii AQP9-associated filopodial extensions preceded actin polymerization, which was in turn crucial for their stability and dynamics, and (iii minute, local reductions in osmolarity immediately initiated small dynamic bleb-like protrusions, the size of which correlated with the reduction in osmotic pressure. Based on this, we present a model for AQP9-induced membrane protrusion, where the interplay of water fluxes through AQP9 and actin dynamics regulate the cellular protrusive and motile activity of cells.

  10. 33 CFR 110.255 - Ponce Harbor, P.R.

    Science.gov (United States)

    2010-07-01

    ... for all types of small craft, including schooners, fishing vessels, yachts and pleasure craft. (5... ANCHORAGE REGULATIONS Anchorage Grounds § 110.255 Ponce Harbor, P.R. (a) Small-craft anchorage. On the...

  11. Installation Restoration Program. Phase 1. Records Search for the 176th Tactical Airlift Group, Kulis Air National Guard Base, Anchorage, Alaska.

    Science.gov (United States)

    1986-04-01

    the team and provided input to this report: Mr. Donato Telesca, Program Manager Mr. Timothy Gardner, Environmental Scientist Mr. Mark Johnson, Geologist...control and waste disposal for seven producing units. Some of the products produced were: rare earths and polishing compounds, raney nickel, silica gel...November 7, 1985. .. ,Pa, A-7 L - L- WV10 TIMOTHY N. GARDNER9 Environmental Scientist U EDUCATION M.A., Environmental Biology, Hood College B.S

  12. The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth.

    NARCIS (Netherlands)

    Spanos, W.C.; Hoover, A.; Harris, G.F.; Wu, S.; Strand, G.L.; Anderson, M.E.; Klingelhutz, A.J.; Hendriks, W.J.A.J.; Bossler, A.D.; Lee, J.H.

    2008-01-01

    The human papillomavirus (HPV) oncogene E6 has been shown to perform multiple functions (p53 degradation, telomerase activation, etc.) that play a role in oncogenic transformation. Beyond known E6 functions, an undefined mechanism that allows cellular invasion requires the E6 PDZ binding motif

  13. "Landslide at sunuapa 401 (hydrocarbon exploration well). Risk reduction by mitigation measures: drainage, piles barrier and anchorages system, shotcrete and reforestation, Chiapas, México".

    Science.gov (United States)

    Cuanalo, Oscar; Polanco, Gabriel; Rivera, Julio

    2013-04-01

    We report the case of a landslide of hydrocarbon exploration well "Sunuapa 401" located in Chiapas, Mexico. First were identified the determinants and triggers factors (morphology, geology, rain, seismic and volcanic activity, human activity, etc); second we assessed the threat, vulnerability and risk from geotechnical stability analysis (safety factor and critical failure surface); third, by using the methodology of valuation factors, stabilization processes were selected and designed, and finally they were built by Petróleos Mexicanos, in order to avoid a disaster (environmental, ecological and social). These construction processes included drainage elements, flattening and benching of slopes, piles barrier and anchors, shotcrete and reforestation.

  14. Forest science research and scientific communities in Alaska: a history of the origins and evolution of USDA Forest Service research in Juneau, Fairbanks, and Anchorage.

    Science.gov (United States)

    Max G. Geier

    1998-01-01

    Research interest in the forests of Alaska can be traced from the 1990s back to 1741, when Georg Steller, the surgeon on Vitus Bering's Russian expedition, visited Kayak Island, collected plants, and recorded his observations. Given the scope and scale of potential research needs and relatively high expenses for travel and logistics in Alaska, support for forest...

  15. Unique Function of the Bacterial Chromosome Segregation Machinery in Apically Growing Streptomyces - Targeting the Chromosome to New Hyphal Tubes and its Anchorage at the Tips.

    Directory of Open Access Journals (Sweden)

    Agnieszka Kois-Ostrowska

    2016-12-01

    Full Text Available The coordination of chromosome segregation with cell growth is fundamental to the proliferation of any organism. In most unicellular bacteria, chromosome segregation is strictly coordinated with cell division and involves ParA that moves the ParB nucleoprotein complexes bi- or unidirectionally toward the cell pole(s. However, the chromosome organization in multiploid, apically extending and branching Streptomyces hyphae challenges the known mechanisms of bacterial chromosome segregation. The complex Streptomyces life cycle involves two stages: vegetative growth and sporulation. In the latter stage, multiple cell divisions accompanied by chromosome compaction and ParAB assisted segregation turn multigenomic hyphal cell into a chain of unigenomic spores. However, the requirement for active chromosome segregation is unclear in the absence of canonical cell division during vegetative growth except in the process of branch formation. The mechanism by which chromosomes are targeted to new hyphae in streptomycete vegetative growth has remained unknown until now. Here, we address the question of whether active chromosome segregation occurs at this stage. Applied for the first time in Streptomyces, labelling of the chromosomal replication initiation region (oriC and time-lapse microscopy, revealed that in vegetative hyphae every copy of the chromosome is complexed with ParB, whereas ParA, through interaction with the apical protein complex (polarisome, tightly anchors only one chromosome at the hyphal tip. The anchor is maintained during replication, when ParA captures one of the daughter oriCs. During spore germination and branching, ParA targets one of the multiple chromosomal copies to the new hyphal tip, enabling efficient elongation of hyphal tube. Thus, our studies reveal a novel role for ParAB proteins during hyphal tip establishment and extension.

  16. Unique Function of the Bacterial Chromosome Segregation Machinery in Apically Growing Streptomyces - Targeting the Chromosome to New Hyphal Tubes and its Anchorage at the Tips.

    Science.gov (United States)

    Kois-Ostrowska, Agnieszka; Strzałka, Agnieszka; Lipietta, Natalia; Tilley, Emma; Zakrzewska-Czerwińska, Jolanta; Herron, Paul; Jakimowicz, Dagmara

    2016-12-01

    The coordination of chromosome segregation with cell growth is fundamental to the proliferation of any organism. In most unicellular bacteria, chromosome segregation is strictly coordinated with cell division and involves ParA that moves the ParB nucleoprotein complexes bi- or unidirectionally toward the cell pole(s). However, the chromosome organization in multiploid, apically extending and branching Streptomyces hyphae challenges the known mechanisms of bacterial chromosome segregation. The complex Streptomyces life cycle involves two stages: vegetative growth and sporulation. In the latter stage, multiple cell divisions accompanied by chromosome compaction and ParAB assisted segregation turn multigenomic hyphal cell into a chain of unigenomic spores. However, the requirement for active chromosome segregation is unclear in the absence of canonical cell division during vegetative growth except in the process of branch formation. The mechanism by which chromosomes are targeted to new hyphae in streptomycete vegetative growth has remained unknown until now. Here, we address the question of whether active chromosome segregation occurs at this stage. Applied for the first time in Streptomyces, labelling of the chromosomal replication initiation region (oriC) and time-lapse microscopy, revealed that in vegetative hyphae every copy of the chromosome is complexed with ParB, whereas ParA, through interaction with the apical protein complex (polarisome), tightly anchors only one chromosome at the hyphal tip. The anchor is maintained during replication, when ParA captures one of the daughter oriCs. During spore germination and branching, ParA targets one of the multiple chromosomal copies to the new hyphal tip, enabling efficient elongation of hyphal tube. Thus, our studies reveal a novel role for ParAB proteins during hyphal tip establishment and extension.

  17. A Novel Rat Model of Orthodontic Tooth Movement Using Temporary Skeletal Anchorage Devices: 3D Finite Element Analysis and In Vivo Validation

    Directory of Open Access Journals (Sweden)

    Neelambar Kaipatur

    2014-01-01

    Full Text Available The aim of this animal study was to develop a model of orthodontic tooth movement using a microimplant as a TSAD in rodents. A finite element model of the TSAD in alveolar bone was built using μCT images of rat maxilla to determine the von Mises stresses and displacement in the alveolar bone surrounding the TSAD. For in vivo validation of the FE model, Sprague-Dawley rats (n=25 were used and a Stryker 1.2 × 3 mm microimplant was inserted in the right maxilla and used to protract the right first permanent molar using a NiTi closed coil spring. Tooth movement measurements were taken at baseline, 4 and 8 weeks. At 8 weeks, animals were euthanized and tissues were analyzed by histology and EPMA. FE modeling showed maximum von Mises stress of 45 Mpa near the apex of TSAD but the average von Mises stress was under 25 Mpa. Appreciable tooth movement of 0.62 ± 0.04 mm at 4 weeks and 1.99 ± 0.14 mm at 8 weeks was obtained. Histological and EPMA results demonstrated no active bone remodeling around the TSAD at 8 weeks depicting good secondary stability. This study provided evidence that protracted tooth movement is achieved in small animals using TSADs.

  18. A Novel Rat Model of Orthodontic Tooth Movement Using Temporary Skeletal Anchorage Devices: 3D Finite Element Analysis and In Vivo Validation.

    Science.gov (United States)

    Kaipatur, Neelambar; Wu, Yuchin; Adeeb, Samer; Stevenson, Thomas; Major, Paul; Doschak, Michael

    2014-01-01

    The aim of this animal study was to develop a model of orthodontic tooth movement using a microimplant as a TSAD in rodents. A finite element model of the TSAD in alveolar bone was built using μCT images of rat maxilla to determine the von Mises stresses and displacement in the alveolar bone surrounding the TSAD. For in vivo validation of the FE model, Sprague-Dawley rats (n = 25) were used and a Stryker 1.2 × 3 mm microimplant was inserted in the right maxilla and used to protract the right first permanent molar using a NiTi closed coil spring. Tooth movement measurements were taken at baseline, 4 and 8 weeks. At 8 weeks, animals were euthanized and tissues were analyzed by histology and EPMA. FE modeling showed maximum von Mises stress of 45 Mpa near the apex of TSAD but the average von Mises stress was under 25 Mpa. Appreciable tooth movement of 0.62 ± 0.04 mm at 4 weeks and 1.99 ± 0.14 mm at 8 weeks was obtained. Histological and EPMA results demonstrated no active bone remodeling around the TSAD at 8 weeks depicting good secondary stability. This study provided evidence that protracted tooth movement is achieved in small animals using TSADs.

  19. Hollow modular anchorage (HMA) screws for anterior transvertebral fixation in high-grade spondylolisthesis cases requiring 360 degrees in-situ fusion.

    Science.gov (United States)

    König, Matthias A; Boszczyk, Bronek M

    2018-03-22

    360 degrees in-situ fusion for high-grade spondylolisthesis showed satisfying clinical long-term results. Combining anterior with posterior surgery increases fusion rates. Anteriorly inserted transvertebral HMA screws could be an alternative to strut graft constructs or cages, avoiding donor site complications. In addition, complete posterior muscle detachment is avoided and the injury risk of neural structures is minimized. This study investigates the use of HMA screws in this context. Five consecutive patients requiring L4-S1 in-situ fusion for isthmic spondylolisthesis (four Grade 3 and one Grade 4) were included. The L5/S1 level was fused with an HMA screw filled with local bone and bone morphogenic protein (BMP2), inserted via the L4/5 disc space level. An L4/5 stand-alone interbody fusion with additional minimal invasive posterior screw fixation was added. Transvertebral insertion of the HMA device was accomplished via a retroperitoneal approach to L4/L5 in all cases without exposure of L5/S1. Blood loss ranged from 150 ml-350 ml. No intraoperative complication occurred. One patient developed posterior wound infection requiring debridement. Solid fusion was confirmed with a CT scan after 6 months in all patients. All patients improved to unrestricted activities of daily living with two being limited by occasional back pain. HMA screws allow for effective lumbosacral fusion via a limited anterior exposure. This is technically easier than posterior exposure of the lumbosacral junction in high-grade spondylolisthesis requiring 360 degrees fusion.

  20. Induction of anchorage-independent growth of human embryonic fibroblasts with a deletion in the short arm of chromosome 11 by human papillomavirus type 16 DNA

    International Nuclear Information System (INIS)

    Smits, H.L.; Raadsheer, E.; Rood, I.; Mehendale, S.; Slater, R.M.; van der Noordaa, J.; Ter Schegget, J.

    1988-01-01

    Human embryonic fibroblasts with a large deletion (11p11.11p15.1) in the short arm of one chromosome 11 (del-11 cells) appeared to be susceptible to transformation by early human papillomavirus type 16 (HPV-16) DNA, whereas diploid human embryonic fibroblasts were not. This difference in susceptibility might be explained by the absence of a tumor suppressor gene located within the deleted part on the short arm of chromosome 11. The presence of abundant viral early-gene transcripts in transformed cells suggests that transformation was induced by an elevated level of an HPV-16 early-gene product(s). The low transcriptional activity of HPV-16 in diploid cells may indicate that cellular genes affect viral transcription. Interruption of the HPV-16 E2 early open reading frame is probably required for high-level HPV-16 early-gene expression driven from the homologous enhancer-promoter region

  1. Wilderness in the Circumpolar North: searching for compatibility in ecological, traditional, and ecotourism values; 2001 May 15-16; Anchorage, AK

    Science.gov (United States)

    Alan E. Watson; Lilian Alessa; Janet Sproull

    2002-01-01

    There are growing pressures on undeveloped (wild) places in the Circumpolar North. Among them are pressures for economic development, oil and gas exploration and extraction, development of geothermal energy resources, development of heavy industry close to energy sources, and lack of appreciation for "other" orientations toward wilderness resources by...

  2. Correction of a Class III malocclusion with over 20 mm of space to close in the maxilla by using miniscrews for extra anchorage.

    NARCIS (Netherlands)

    Breuning, K.H.

    2008-01-01

    Unilateral closure of maxillary extraction spaces in patients with Class III malocclusion can be challenging. This case report describes the closure of first premolar and first molar extraction spaces in a patient with a Class III dental relationship. Two miniscrews were used for intraoral skeletal

  3. Jump transition observed in translocation time for ideal poly-X proteinogenic chains as a result of competing folding and anchoraging contributions

    Science.gov (United States)

    Vélez-Pérez, José Antonio; Olivares-Quiroz, Luis

    2017-01-01

    In this work we analyze the translocation of homopolymer chains poly-X , where X represents any of the 20 naturally occurring amino acid residues, in terms of size N and single-helical propensity ω . We provide an analytical framework to calculate both the free energy F of translocation and the translocation time τ as a function of chain size N , energies U and ɛ of the unfolded and folded states, respectively. Our results show that free energy F has a characteristic bell-shaped barrier as function of the percentage of monomers translocated. Inclusion of single-helical propensity ω associated to monomer X and chain's native energy ɛ in the translocation model increases the energy barrier Δ F up to one order of magnitude as compared with the well-known Gaussian chain model. Computation of the mean first-passage time as function of chain size N shows that the translocation time τ exhibits a significant jump of several orders of magnitude at a critical chain size N . This jump markedly slows down translocation of chains larger than N . Existence of the transition jump of τ has been observed experimentally at least in poly(ethylene oxide) chains [R. P. Choudhury, P. Galvosas, and M. Schönhoff, J. Phys. Chem. B 112, 13245 (2008)], 10.1021/jp804680q. Our results suggest the transition jump of τ as a function of N may be a very well spread feature throughout translocation of poly-X chains.

  4. Stonke Construction Information Sheet

    Science.gov (United States)

    Stonke Construction (the Company) is located in Anchorage, Alaska. The settlement involves renovation activities conducted at properties constructed prior to 1978, located in and around Anchorage, Alaska.

  5. 33 CFR 110.156 - Randall Bay, Freeport, Long Island, N.Y.

    Science.gov (United States)

    2010-07-01

    ... Island, N.Y. 110.156 Section 110.156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.156 Randall Bay, Freeport, Long Island, N.Y. (a) The anchorage grounds. Southward of a line 312 feet south of and parallel to the south side...

  6. 33 CFR 110.208 - Buffalo Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo Harbor, N.Y. 110.208 Section 110.208 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.208 Buffalo Harbor, N.Y. (a) The anchorage grounds—(1...

  7. 33 CFR 110.238 - Apra Harbor, Guam.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. 110.238 Section 110.238 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.238 Apra Harbor, Guam. (a) The anchorage grounds (Datum: WGS...

  8. 33 CFR 110.150 - Block Island Sound, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Block Island Sound, N.Y. 110.150 Section 110.150 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.150 Block Island Sound, N.Y. (a) The anchorage ground. A 3/4...

  9. Manejo del anclaje farmacol??gico en ortodoncia mediante el uso de osteoprotegerina y zoledronato en un modelo de movimiento dentario en rata = Pharmacological management of anchorage in orthodontics based on osteoprotegerin and zoledronate in a rat tooth movement model

    OpenAIRE

    Fern??ndez Gonz??lez, Felipe Jos??

    2017-01-01

    126 p. Los mecanismos celulares involucrados en el movimiento dentario todav??a no han sido esclarecidos en su totalidad, aunque se acepta con car??cter general que son los mismos que regulan la remodelaci??n ??sea que se observa tras la aplicaci??n de fuerzas mec??nicas (Yokoya y Cols., 1997). En la pr??ctica asistencial ortod??ncica, se producen situaciones en las cuales, por la complejidad del caso o a las caracter??sticas del paciente, se requieren unas condiciones especiales de an...

  10. Preliminary Geologic Map of the Cook Inlet Region, Alaska-Including Parts of the Talkeetna, Talkeetna Mountains, Tyonek, Anchorage, Lake Clark, Kenai, Seward, Iliamna, Seldovia, Mount Katmai, and Afognak 1:250,000-scale Quadrangles

    Science.gov (United States)

    Wilson, Frederic H.; Hults, Chad P.; Schmoll, Henry R.; Haeussler, Peter J.; Schmidt, Jeanine M.; Yehle, Lynn A.; Labay, Keith A.; Shew, Nora B.

    2009-01-01

    The growth in the use of Geographic Information Systems (GIS) has highlighted the need for digital geologic maps that have been attributed with information about age and lithology. Such maps can be conveniently used to generate derivative maps for manifold special purposes such as mineral-resource assessment, metallogenic studies, tectonic studies, and environmental research. This report is part of a series of integrated geologic map databases that cover the entire United States. Three national-scale geologic maps that portray most or all of the United States already exist; for the conterminous U.S., King and Beikman (1974a,b) compiled a map at a scale of 1:2,500,000, Beikman (1980) compiled a map for Alaska at 1:2,500,000 scale, and for the entire U.S., Reed and others (2005a,b) compiled a map at a scale of 1:5,000,000. A digital version of the King and Beikman map was published by Schruben and others (1994). Reed and Bush (2004) produced a digital version of the Reed and others (2005a) map for the conterminous U.S. The present series of maps is intended to provide the next step in increased detail. State geologic maps that range in scale from 1:100,000 to 1:1,000,000 are available for most of the country, and digital versions of these state maps are the basis of this product. The digital geologic maps presented here are in a standardized format as ARC/INFO export files and as ArcView shape files. The files named __geol contain geologic polygons and line (contact) attributes; files named __fold contain fold axes; files named __lin contain lineaments; and files named __dike contain dikes as lines. Data tables that relate the map units to detailed lithologic and age information accompany these GIS files. The map is delivered as a set 1:250,000-scale quadrangle files. To the best of our ability, these quadrangle files are edge-matched with respect to geology. When the maps are merged, the combined attribute tables can be used directly with the merged maps to make derivative maps.

  11. Molecular mechanisms of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced inverted U-shaped dose responsiveness in anchorage independent growth and cell proliferation of human breast epithelial cells with stem cell characteristics

    International Nuclear Information System (INIS)

    Ahn, Nam-Shik; Hu, Hongbo; Park, Jin-Sung; Park, Joon-Suk; Kim, Jong-Sik; An, Sungwhan; Kong, Gu; Aruoma, Okezie I.; Lee, Yong-Soon; Kang, Kyung-Sun

    2005-01-01

    Although 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has a variety of carcinogenic and noncarcinogenic effects in experimental animals, its role in human carcinogenicity remain controversial. A simian virus 40-immortalized cell line from normal human breast epithelial cells with stem cells and luminal characteristics (M13SV1) was used to study whether TCDD can induce AIG positive colony formation and cause increased cell numbers in a inverted U-shaped dose-response manner. TCDD activated Akt, ERK2, and increased the expression of CYP1A1, PAI-2, IL-lb mRNA, and ERK2 protein levels. TCDD was able to increased phosphorylation and expression of ERK2 in same dose-response manner as AIG positive colony formation. Thus, TCDD induced tumorigenicity in M13SV1, possibly through the phosphorylation of ERK2 and/or Akt. Further, cDNA microarray with 7448 sequence-verified clones was used to profile various gene expression patterns after treatment of TCDD. Three clear patterns could be delineated: genes that were dose-dependently up-regulated, genes expressed in either U-shape and/or inverted U-shape. The fact that these genes are intrinsically related to breast epithelial cell proliferation and survival clearly suggests that they may be involved in the TCDD-induced breast tumorigenesis

  12. 76 FR 71321 - North Pacific Fishery Management Council; Public Meetings

    Science.gov (United States)

    2011-11-17

    ... public meetings, December 5-13, 2011 at the Anchorage Hilton Hotel. DATES: The Council will begin its... sessions. ADDRESSES: The meetings will be held at the Hilton Hotel, 500 West Third Avenue, Anchorage, AK...

  13. 76 FR 25308 - Marine Mammals

    Science.gov (United States)

    2011-05-04

    ...-XA165 Marine Mammals AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... Jennifer Burns, Ph.D., University of Alaska Anchorage, Biology Department, 3101 Science Circle, Anchorage, AK, has been issued a permit to conduct [[Page 25309

  14. 77 FR 303 - Sunshine Act Notice

    Science.gov (United States)

    2012-01-04

    ...: Sheraton Anchorage Hotel, 401 E. 6th Avenue, Anchorage, AK 99501; telephone: (907) 276-8700; fax: (907) 343... limited to discussions of internal agency processes, personnel, and the budget of the Commission. All...

  15. Orthodontic intrusion : Conventional and mini-implant assisted intrusion mechanics

    Directory of Open Access Journals (Sweden)

    Anup Belludi

    2012-01-01

    intrusion has revolutionized orthodontic anchorage and biomechanics by making anchorage perfectly stable. This article addresses various conventional clinical intrusion mechanics and especially intrusion using mini-implants that have proven effective over the years for intrusion of maxillary anteriors.

  16. An Innovative Treatment Strategy to Counteract Retroactive Forces In Bimaxillary Dentoalveolar Cases

    Directory of Open Access Journals (Sweden)

    Reena R Kumar

    2010-01-01

    This paper presents a case report of a 30 yrs old male patient with Class I Bimaxillary Protrusion treated using innovative lingual forces with a labial appliance (without any additional intraoral or extraoral anchorage devices effectively with negligible anchorage loss.

  17. 33 CFR 110.214 - Los Angeles and Long Beach harbors, California.

    Science.gov (United States)

    2010-07-01

    ...) Radio communications for port entities governing anchorages are as follows: Los Angeles-Long Beach... Defense charter, and vessels requiring use of the explosives anchorage. c. Bunkering and lightering are...

  18. 33 CFR 110.67 - Delaware River, Essington, Pa.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Delaware River, Essington, Pa. 110.67 Section 110.67 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.67 Delaware River, Essington, Pa. North of...

  19. 33 CFR 110.74b - Apollo Beach, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a point...

  20. 33 CFR 110.8 - Lake Champlain, N.Y. and Vt.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lake Champlain, N.Y. and Vt. 110... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.8 Lake Champlain, N.Y. and Vt. (a) Ticonderoga, N.Y. An area shoreward of a line bearing 312° from Ticonderoga Light to the southeast corner of the...

  1. 33 CFR 110.48 - Thompson Cove on east side of Pawcatuck River below Westerly, R.I.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Thompson Cove on east side of..., DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.48 Thompson... channelward end of Thompson Dock at the northern end of Thompson Cove 184° to the shore at the southern end of...

  2. 33 CFR 110.73a - Indian River at Sebastian, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Indian River at Sebastian, Fla. 110.73a Section 110.73a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73a Indian River at Sebastian, Fla. Beginning at a point on the shoreline at latitude...

  3. 78 FR 78824 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-12-27

    ...-17 at the Hilton Hotel, 500 West Third Avenue, Katmai/King Salmon, Anchorage, AK. DATES: The workshop... Anchorage Hilton Hotel, 500 West Third Avenue, Anchorage, AK. Council address: North Pacific Fishery... and Management Act (Magnuson-Stevens Act), those issues may not be the subject of formal action during...

  4. Stone cladding engineering

    National Research Council Canada - National Science Library

    Camposinhos, Rui de Sousa

    2014-01-01

    ...) for the most commonly used modern anchorage systems. Calculation examples allow designers to solve several anchorage engineering problems in a detailed and objective manner, underlining the key parameters. The design of the anchorage metal parts, either in stainless steel or aluminum, is also presented.

  5. 33 CFR 110.168 - Hampton Roads, Virginia and adjacent waters (Datum: NAD 83).

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hampton Roads, Virginia and adjacent waters (Datum: NAD 83). 110.168 Section 110.168 Navigation and Navigable Waters COAST GUARD..., Virginia and adjacent waters (Datum: NAD 83). (a) Anchorage Grounds—(1) Anchorage A [Naval Anchorage]. The...

  6. 33 CFR 110.74c - Bahia de San Juan, PR.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Bahia de San Juan, PR. 110.74c Section 110.74c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74c Bahia de San Juan, PR. The waters of San Antonio...

  7. 33 CFR 110.58 - Cos Cob Harbor, Greenwich, Conn.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cos Cob Harbor, Greenwich, Conn. 110.58 Section 110.58 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.58 Cos Cob Harbor, Greenwich, Conn. (a) Area A...

  8. 33 CFR 110.128c - Island of Kauai, Hawaii.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Island of Kauai, Hawaii. 110.128c Section 110.128c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.128c Island of Kauai, Hawaii. (a) Nawiliwili Bay. The...

  9. 33 CFR 110.128b - Island of Hawaii, Hawaii.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Island of Hawaii, Hawaii. 110.128b Section 110.128b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.128b Island of Hawaii, Hawaii. (a) Hilo Bay...

  10. 33 CFR 110.170 - Lockwoods Folly Inlet, N.C.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lockwoods Folly Inlet, N.C. 110.170 Section 110.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.170 Lockwoods Folly Inlet, N.C. (a) Explosives...

  11. 33 CFR 110.129a - Apra Harbor, Guam. (Datum: WGS 84)

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. (Datum: WGS 84) 110.129a Section 110.129a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.129a Apra Harbor, Guam. (Datum: WGS 84) (a...

  12. Exterior beam-column joint study with non-conventional ...

    Indian Academy of Sciences (India)

    Reinforced concrete structures beam-column joints are the most critical regions in seismic prone areas. Proper reinforcement anchorage is essential to enhance the performance of the joints. An attempt has been made to appraise the performance of the anchorages and joints. The anchorages are detailed as per ACI-352 ...

  13. 33 CFR 110.25 - Salem Sound, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Salem Sound, Mass. 110.25 Section 110.25 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.25 Salem Sound, Mass. (a) Beverly Harbor, north of Salem...

  14. 33 CFR 110.27 - Lynn Harbor in Broad Sound, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lynn Harbor in Broad Sound, Mass. 110.27 Section 110.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.27 Lynn Harbor in Broad Sound, Mass. North of...

  15. 33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Thomas Harbor, Charlotte... SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.250 St. Thomas Harbor, Charlotte Amalie.... Thomas, V.I. of the United States and approaches thereto, including all waters under its jurisdiction, as...

  16. 33 CFR 110.197 - Galveston Harbor, Bolivar Roads Channel, Texas.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Galveston Harbor, Bolivar Roads Channel, Texas. 110.197 Section 110.197 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.197 Galveston Harbor, Bolivar...

  17. 33 CFR 110.185 - Atlantic Ocean, off the Port of Palm Beach, FL.

    Science.gov (United States)

    2010-07-01

    ... Palm Beach, FL. 110.185 Section 110.185 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... of Palm Beach, FL. (a) The anchorage grounds. (1) Anchorage A. The waters lying within an area... Palm Beach, shall only anchor within the anchorage areas hereby defined and established, except in...

  18. Initial forces experienced by the anterior and posterior teeth during dental-anchored or skeletal-anchored en masse retraction in vitro.

    Science.gov (United States)

    Lee, David; Heo, Giseon; El-Bialy, Tarek; Carey, Jason P; Major, Paul W; Romanyk, Dan L

    2017-07-01

    To investigate initial forces acting on teeth around the arch during en masse retraction using an in vitro Orthodontic SIMulator (OSIM). The OSIM was used to represent the full maxillary arch in a case wherein both first premolars had been extracted. Dental and skeletal anchorage to a posted archwire and skeletal anchorage to a 10-mm power arm were all simulated. A 0.019 × 0.025-inch stainless steel archwire was used in all cases, and 15-mm light nickel-titanium springs were activated to approximately 150 g on both sides of the arch. A sample size of n = 40 springs were tested for each of the three groups. Multivariate analysis of variance (α = 0.05) was used to determine differences between treatment groups. In the anterior segment, it was found that skeletal anchorage with power arms generated the largest retraction force (P forces on the unit were generated using skeletal anchorage, followed by skeletal anchorage with power arms, and finally dental anchorage. Power arms were found to generate larger intrusive forces on the lateral incisors and extrusive forces on the canines than on other groups. For the posterior anchorage unit, dental anchorage generated the largest protraction and palatal forces. Negligible forces were measured for both skeletal anchorage groups. Vertical forces on the posterior unit were minimal in all cases (forces to retract the anterior teeth during en masse retraction. Skeletal anchorage reduced forces on the posterior teeth but introduced greater vertical forces on the anterior teeth.

  19. L’ancrage squelettique au passé, présent et futur

    DEFF Research Database (Denmark)

    Melsen, Birte; Dalstra, Michel

    2017-01-01

    INTRODUCTION: Skeletal anchorage was not introduced as an alternative to conventional anchorage modalities. The first skeletal anchorage was a ligature through a hole in the infrazygomatic crest. This was replaced by surgical screws and finally the TADs, which were optimized with respect to the m......INTRODUCTION: Skeletal anchorage was not introduced as an alternative to conventional anchorage modalities. The first skeletal anchorage was a ligature through a hole in the infrazygomatic crest. This was replaced by surgical screws and finally the TADs, which were optimized with respect...... to the material and morphology, were developed. A bracket-like head allows for the use of the mini-implant as indirect anchorage, but should not be a tool for lost control resulting from badly planned biomechanics or failing compliance. Skeletal anchorage should serve as an adjunct to correct biomechanics......, to enable treatments that could not be performed prior to the introduction of skeletal anchorage. MATERIALS AND METHODS: The aim of this study was to test the hypothesis that temporary anchorage mini-screws help maintain bone density, height and width of alveolar processes in the extraction sites, and thus...

  20. 33 CFR 110.85 - Niagara River, Youngstown, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Niagara River, Youngstown, N.Y... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.85 Niagara River, Youngstown, N.Y. (a) Area 1... of the Niagara River at latitude 43°14′33″ N, longitude 79°03′7.5″ W; thence westerly to a point at...

  1. 9 CFR 93.303 - Ports designated for the importation of horses.

    Science.gov (United States)

    2010-01-01

    ... Sweetgrass, Montana; Alexandria Bay, Buffalo, and Champlain, New York; Dunseith, Pembina, and Portal, North... inspection facilities: Anchorage and Fairbanks, Alaska; San Diego, California; Jacksonville, St. Petersburg...

  2. 9 CFR 93.403 - Ports designated for the importation of ruminants.

    Science.gov (United States)

    2010-01-01

    ..., and Champlain, New York; Dunseith, Pembina, and Portal, North Dakota; Derby Line and Highgate Springs... facilities: Anchorage and Fairbanks, Alaska; San Diego, California; Jacksonville, St. Petersburg-Clearwater...

  3. 7 CFR Appendix A to Part 661 - Availability of Information

    Science.gov (United States)

    2010-01-01

    ... 311, Auburn, Ala. 36830. State Conservationist, Suite 129, Professional Bldg., 2221 East Northern Lights Blvd., Anchorage, Alaska 99504. State Conservationist, 230 North 1st Ave., Federal Bldg., Phoenix...

  4. Heuristics and anchorages in the formation of prices in supermarkets Heurísticas y ancorajes en la formación de los precios en supermercados Heurísticas e ancoragens na formação dos preços em supermercados

    Directory of Open Access Journals (Sweden)

    Roberto Brazileiro Paixão

    2010-12-01

    Full Text Available This paper analyzes the process of the formation of prices emphasizing the phenomenon of anchoring on the digit before the period, which assumes that in a simplified decision-making process, consumers might stress only the digit before the period. Therefore the cents would not be perceived and a price such as $ 2.99 would be mentally registered as only $ 2.00. One study examined 4.144 prices on gondolas and 52 prices on tabloids at three supermarket chains in Salvador, Bahia. Results disclosed a significant practice of pricing with the higher number of cents that is consistent with anchoring. A second separate study sought reasons for the phenomenon by conducting an experiment with 96 consumers where each analyzed ten prices of different products for a total of 952 observations. These results revealed that when customers are faced with a price and different cents, they have randomly distributed perceptions between the full upper and lower price. Although the anchoring described has not been proven, random distribution of responses is coherent with the systematic practice of prices with a larger number of cents since the perception of consumers would not be affected by the cents.Este artículo buscó analizar el proceso de formación de precios, enfatizando el fenómeno del ancoraje del dígito izquierdo, que supone que en un proceso simplificado de tomar decisiones los consumidores podrían registrar apenas el dígito izquierdo, anterior a la coma. Los centavos no serían percibidos, y un precio como R$ 2,99 sería registrado mentalmente como apenas R$ 2,00. Dos encuestas distintas fueron hechas. La primera analizó 4.144 precios en anaqueles y 52 precios en tabloides de tres redes de supermercados de Salvador, Bahía, y constató la práctica significativa de precios con centavos más altos, coherente con el ancoraje. La segunda encuesta buscó encontrar las razones para el fenómeno, realizando una experiencia con 96 consumidores, cada uno analizando diez precios de productos diferentes, lo que completó 952 observaciones. Los resultados de la segunda encuesta indican que cuando se ven delante de precios con centavos diferentes, los consumidores presentan percepciones aleatoriamente distribuidas entre el precio entero superior y el inferior. Aunque el ancoraje en el dígito izquierdo no haya sido comprobado, la distribución aleatoria de las respuestas es coherente con la práctica sistemática de precios con centavos más elevados, ya que la percepción del consumidor no seria afectada por los centavos.Este artigo buscou analisar o processo de formação de preços, enfatizando o fenômeno da ancoragem do dígito esquerdo, que supõe que em um processo simplificado de tomada de decisão consumidores poderiam registrar apenas o dígito esquerdo, anterior à virgula. Os centavos não seriam percebidos, e um preço como R$ 2,99 seria registrado mentalmente como apenas R$ 2,00. Duas pesquisas distintas foram feitas. A primeira analisou 4.144 preços em gôndolas e 52 preços em tabloides de três redes de supermercados de Salvador, Bahia, e constatou a prática significativa de preços com centavos mais altos, coerente com a ancoragem. A segunda pesquisa procurou encontrar as razões para o fenômeno, realizando experimento com 96 consumidores, cada um analisando dez preços de produtos diferentes, o que totalizou 952 observações. Os resultados da segunda pesquisa indicam que quando se veem diante de preços com centavos diferentes, os consumidores apresentam percepções aleatoriamente distribuídas entre o preço inteiro superior e o inferior. Embora a ancoragem no dígito esquerdo não tenha sido comprovada, a distribuição aleatória das respostas é coerente com a prática sistemática de preços com centavos mais elevados, já que a percepção do consumidor não seria afetada pelos centavos.

  5. Exterior beam-column joint study with non-conventional ...

    Indian Academy of Sciences (India)

    Keywords. Reinforced concrete; beam-column joint; seismic susceptibility; mechanical anchorage; ductility; reversal loading. 1. Introduction. Beam-column joints in seismically susceptible zones are critical regions in the reinforced con- crete framed structure. Proper anchorage and joint details of reinforcement are essential.

  6. 75 FR 54092 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-09-03

    ... 28th, 2010 at the Anchorage Hilton Hotel. DATES: The meeting will be held on September 28, 2010, from 9 a.m. to 5 p.m. ADDRESSES: The meeting will be held at the Anchorage Hilton Hotel, 500 West 3rd...

  7. 77 FR 48159 - Tribal Consultation Meeting

    Science.gov (United States)

    2012-08-13

    ... Anchorage Hotel, 500 West Third Avenue, Anchorage, AK 99501. FOR FURTHER INFORMATION CONTACT: Ann Linehan... a brief description of the topic area, along with the name and contact information of the suggested... each report without attribution, along with topics of concern and recommendations. Hotel and logistical...

  8. 33 CFR 110.195 - Mississippi River below Baton Rouge, LA, including South and Southwest Passes.

    Science.gov (United States)

    2010-07-01

    ... anchorage is a line parallel to the nearest bank 1,000 feet from the water's edge into the river as measured... anchorage is a line parallel to the nearest bank 400 feet from the water's edge into the river as measured... line parallel to the nearest bank 400 feet from the water's edge into the river as measured from the...

  9. 33 CFR 110.50 - Stonington Harbor, Conn.

    Science.gov (United States)

    2010-07-01

    ...′02″, longitude 71°54′34.3″; thence along the shoreline to the point of beginning. (c) Area No. 3... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.50 Stonington Harbor, Conn. (a) Area No. 1. Beginning at... along the shoreline to the point of beginning. (b) Area No. 2. Beginning at a point on the shoreline at...

  10. 78 FR 14984 - Marine Mammals; File No. 17411

    Science.gov (United States)

    2013-03-08

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XC541 Marine Mammals; File No. 17411 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric.... Jennifer Burns, University of Alaska Anchorage, Biology Department, Anchorage, AK, has applied in due form...

  11. 76 FR 4091 - Marine Mammals; File No. 15510

    Science.gov (United States)

    2011-01-24

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XA165 Marine Mammals; File No. 15510 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... Jennifer Burns, Ph.D., University of Alaska Anchorage, Biology Department, 3101 Science Circle, Anchorage...

  12. Surgical Difficulties, Success, and Complication Rates of ...

    African Journals Online (AJOL)

    2017-05-22

    May 22, 2017 ... orthodontic therapy use teeth, extraoral and/or intermaxillary appliances for anchorage. For orthodontic anchorage, orthodontic implants (retromolar implants, miniscrews, pins, and palatal onplants) miniplates, fixation wires have been used frequently.[3] Over several years, bone-anchored orthodontic chin ...

  13. Barriers and facilitators to the implementation of orthodontic mini-implants in clinical practice: a protocol for a systematic review and meta-analysis

    NARCIS (Netherlands)

    Meursinge Reynders, Reint; Ronchi, Laura; Ladu, Luisa; Di Girolamo, Nicola; de Lange, Jan; Roberts, Nia; Mickan, Sharon

    2016-01-01

    Most orthodontic treatment plans need some form of anchorage to control the reciprocal forces of tooth movement. Orthodontic mini implants (OMIs) have been hailed for having revolutionized orthodontics, because they provide anchorage without depending on the collaboration of patients, they have a

  14. Failure modes of prestressed CFRP rods in a wedge anchored set-up

    DEFF Research Database (Denmark)

    Bennitz, Anders; Schmidt, Jacob Wittrup; Täljsten, Björn

    2009-01-01

    on how these failures can be avoided in theory and practice. From the experiences gained in the project, it is concluded that it is a challenging task to create a fully mechanical anchorage for CFRP tendons and that the failure margins are small between a successful and an unsuccesful anchorage system....

  15. 23 CFR Appendix C to Part 658 - Trucks Over 80,000 Pounds on the Interstate System and Trucks Over STAA Lengths on the National...

    Science.gov (United States)

    2010-04-01

    ... accommodation are required. Routes From To AK-1 Anchorage (Potter Weigh Station) Palmer (Palmer-Wasilla Highway... Anchorage (Potter Weigh Station) Jct. AK-3. AK-3 Jct. AK-1 Fairbanks (Gaffney Road Junction) LEGAL CITATIONS... front of the first box to the rear of the second box may not exceed 58 feet. A combination of vehicles...

  16. 33 CFR 110.75 - Corpus Christi Bay, Tex.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Corpus Christi Bay, Tex. 110.75... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.75 Corpus Christi Bay, Tex. (a) South area. Southward of... said breakwater; and eastward of the Corpus Christi sea wall. ...

  17. Failure modes of prestressed CFRP rods in a wedge anchored set-up

    DEFF Research Database (Denmark)

    Bennitz, Anders; Schmidt, Jacob Wittrup; Täljsten, Björn

    2009-01-01

    on how these failures can be avoided in theory and practice. From the experiences gained in the project, it is concluded that it is a challenging task to create a fully mechanical anchorage for CFRP tendons and that the failure margins are small between a successful and an unsuccesful anchorage system.......In the process of developing a new wedge anchorage to anchor prestressed CFRP rods, five different anchorage designs were manufactured. These designs have led to a constantly increased ultimate failure load of the prestressing system and an eventual load level above 95% of the ultimate failure load...... of the rod was achieved. If 100% efficiency is achieved the anchorage does not reduce the capacity of the system, but failure is then governed by the capacity of the rod itself, which is considered favourable and required by several guidelines. In the process seven different failure modes were identified...

  18. Development, testing and installation of prestressing of the PCPV's at Hinkley Point B and Hunterston B

    International Nuclear Information System (INIS)

    Taylor, S.J.; Eadie, D.McD.

    1976-01-01

    In order to keep the walls of the PCPVs at Hinkley Point B and Hunterston B as thin as possible it was desirable to have a prestressing system which permitted close spacing of the tendons and anchorages. A seven strand tendon system was adopted in which the strands are individually anchored by the well-established wedge and barrel system. The seven anchorages bear on to a square plate which transmits the anchorage load to the concrete via a cast steel trumpet. These seven strand anchorages are arranged in groups of four and precast into a steel box as an anchorage unit with an ultimate tendon load of about 1050 tonnes. The development leading up to the adoption of this prestressing system and anchorage arrangement is described. Full size proving tests were carried out on the four tendon anchorage box unit, together with an alternative arrangement using a square helix of bonded reinforcement. Information is given on the friction tests carried out on the completed vessel, prestressing of the PCPVs and the corrosion prevention methods adopted. (author)

  19. Development of Mechanical Anchor for CFRP Tendons Using Integrated Sleeve

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Bennitz, Anders; Täljsten, Björn

    2010-01-01

    A durable and very efficient external strengthening system is achieved if steel tendons for post-tensioning applications can be replaced with CFRP (Carbon Fibre Reinforced Polymer) tendons and if reliable anchorage systems are developed,. This paper presents a newly developed and simple-to-use two...... in the longitudinal direction. Evaluation of the failure modes during testing was one of the main keys in achieving an increasingly better performance of the anchorage until the final anchorage was developed. The obtained failure modes are therefore described to enlighten the importance of addressing them when...

  20. The use of implants at an increased vertical dimension of occlusion to correct a scissor bite: a case report.

    Science.gov (United States)

    Wilson, Gwen Benny; Kidner, Giles; Hemmings, Kenneth

    2008-06-01

    Traditional methods of achieving anchorage for orthodontic treatment are dependant on the presence of a sufficient number of teeth with adequate root support. With the success and predictability of osseo-integration, dental implants are being used frequently to obtain absolute anchorage. This case report illustrates the successful use of implants with a combined orthodontic-restorative approach to obtain anchorage in a partially dentate patient to correct a transverse cross-bite (scissor bite) relationship. The implants were subsequently restored to replace missing posterior teeth. The importance of a multi-disciplinary approach to planning and close liaison between the orthodontist, surgeon and restorative dentist during the treatment phase are discussed.

  1. Mini-implant-supported sliding jig.

    Science.gov (United States)

    Pattabiraman, Vinod; Kumari, Shashikala; Sood, Raghav

    2011-01-01

    Maximum anchorage situations require appropriate anchorage control from the very beginning. This includes control of anchorage in the anteroposterior as well as vertical directions. The requirement is more critical in patients with vertical growth patterns. Loss of anchorage in such situations requires recovery mechanics that will not tax the anchor teeth in any direction while maximizing efficiency. This article describes the use of a mini-implant-supported sliding jig in one such case where unilateral anchor loss in the maxillary arch was observed. A modified sliding jig was supported with Class II elastics stretched from a mini-implant placed in the mandible. With little patient compliance, the mini-implant was used to distalize the maxillary molar to regain the lost space and achieve ideal results in the most efficient way.

  2. 33 CFR 110.216 - Pacific Ocean at Santa Catalina Island, Calif.

    Science.gov (United States)

    2010-07-01

    ... place are prohibited. (4) The instructions of the Captain of the Port requiring vessels to anchor bow and stern, or with two bow anchors, or requiring shifting the anchorage of any vessel within the...

  3. 78 FR 54669 - Exxon Valdez Oil Spill Public Advisory Committee

    Science.gov (United States)

    2013-09-05

    .... ADDRESSES: First floor conference room, Glenn Olds Hall, 4210 University Drive, Anchorage, Alaska. FOR... public. Willie R. Taylor, Director, Office of Environmental Policy and Compliance. [FR Doc. 2013-21569...

  4. Evaluation of bent caps in reinforced concrete deck girder bridges : part 2.

    Science.gov (United States)

    2008-09-01

    This report describes research conducted to enable evaluation of existing vintage bent cap beams in reinforced concrete : deck girder bridges. The report is organized into two parts: 1) flexural anchorage capacity response and prediction of : reduced...

  5. Evaluation of bent caps in reinforced concrete deck girder bridges : part 1.

    Science.gov (United States)

    2008-09-01

    This report describes research conducted to enable evaluation of existing vintage bent cap beams in reinforced concrete : deck girder bridges. The report is organized into two parts: 1) flexural anchorage capacity response and prediction of : reduced...

  6. 77 FR 52674 - Fisheries of the Exclusive Economic Zone Off Alaska; Groundfish Fisheries in the Bering Sea and...

    Science.gov (United States)

    2012-08-30

    ... Dillingham/Katmai room at the Hilton Hotel, 500 West 3rd Street, Anchorage, AK. You may submit comments on... the legal authority, history of the Steller sea lion protection measures, litigation, potential...

  7. 33 CFR 110.155 - Port of New York.

    Science.gov (United States)

    2010-07-01

    ... a line from thence to Smoking Point. (j) Raritan Bay—(1) Anchorage No. 44. An area in Raritan Bay..., in pounds Anchor type Anchor scope Chain size in inches Pendant length in feet Pendant safe working...

  8. 75 FR 17900 - Fisheries of the South Atlantic, Gulf of Mexico, and Caribbean; Southeastern Data, Assessment...

    Science.gov (United States)

    2010-04-08

    .... ADDRESSES: The meeting will be held at the Hotel Captain Cook, 939 West 5th Avenue, Anchorage, AK 99501... assessment scheduling for 2010-2015, and discuss the SEDAR budget, conflict of interest policies, and...

  9. 75 FR 23244 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2010-05-03

    .... ADDRESSES: The meeting will be held at the Hotel Captain Cook, 939 W 5th Avenue, Anchorage, AK 99501...); Marine Protection Area (MPA) nominations; President's budget and other budget issues, 2010 National SSC...

  10. 77 FR 32978 - Exxon Valdez Oil Spill Trustee Council; Notice of Meeting

    Science.gov (United States)

    2012-06-04

    ... Hall Conference Room, 4210 University Drive, Anchorage, Alaska. FOR FURTHER INFORMATION CONTACT... R. Taylor, Director, Office of Environmental Policy and Compliance. [FR Doc. 2012-13380 Filed 6-1-12...

  11. The Role of a Novel Protease NES1 in Breast Cancer

    National Research Council Canada - National Science Library

    Band, Vimla

    2001-01-01

    ...). IVGG sequence is required for salt bridge formation. Transfection of NESl cDNA into NESl-negative breast cancer cell line suppressed the anchorage-independent growth and tumor formation in nude mice...

  12. 19 CFR 12.26 - Importations of wild animals, fish, amphibians, reptiles, mollusks, and crustaceans; prohibited...

    Science.gov (United States)

    2010-04-01

    .... (3) Wild ruminants (all animals which chew the cud, such as cattle, buffaloes, sheep, goats, deer..., Texas Los Angeles, California San Francisco, California Anchorage, Alaska, Honolulu, Hawaii O'Hare...

  13. Insertion torque values and success rates for paramedian insertion of orthodontic mini-implants : A retrospective study.

    Science.gov (United States)

    Di Leonardo, Bruno; Ludwig, Björn; Lisson, Jörg Alexander; Contardo, Luca; Mura, Rossano; Hourfar, Jan

    2018-03-01

    Orthodontic mini-implants (OMIs) are a reliable method to provide temporary orthodontic anchorage. We hypothesized that there is an optimal insertion torque (10 Ncm) will decrease the success rate and increase palatal OMI failure was rejected.

  14. 76 FR 29640 - Special Local Regulations for Marine Events; Chester River, Chestertown, MD

    Science.gov (United States)

    2011-05-23

    ... 200 yards to an anchorage location, embarking and disembarking Tea Party actors by dinghy, and then... reference Datum NAD 1983. (b) Definitions: (1) Coast Guard Patrol Commander means a commissioned, warrant...

  15. Performance of depressed medians on divided highways in Alaska.

    Science.gov (United States)

    2015-07-01

    The population of Alaska especially the city of Anchorage is steadily increasing. As a result, traffic volumes are higher and demands to : add lanes to existing highways is increasing in order to relieve congestion. In Alaska, an expressway or freewa...

  16. 9 CFR 93.107 - Special provisions.

    Science.gov (United States)

    2010-01-01

    ... following ports of entry: Anchorage, AK; Fairbanks, AK; Los Angeles, CA; San Diego, CA; Denver, CO; Miami...; Pembina, ND; Portal, ND; Portland, OR; San Juan, PR; Houston, TX; Highgate Springs, VT; Seattle, WA; and...

  17. 9 CFR 93.703 - Ports designated for importation.

    Science.gov (United States)

    2010-01-01

    ... ports. Anchorage and Fairbanks, AK; San Diego and Los Angeles, CA; Denver, CO; Jacksonville, Miami, St...; Alexandria Bay, Buffalo, and Champlain, NY; Dunseith, Pembina, and Portal, ND; Derby Line and Highgate...

  18. Penutupan Ruang Pasca Pencabutan pada Perawatan Ortodonti

    Directory of Open Access Journals (Sweden)

    Monica GA Monica GA

    2015-10-01

    Full Text Available Orthodontic space closure of every single patient should be planned individually based on the diagnosis and treatment plan. Failure on this procedure due to anchorage loss will inhibit correction of the bimaxillary protrusion because mesial movement of the posterior teeth occupied most of the premolar extraction space. The diagnosis and treatment plan should be considered carefully especially those of the ampunt of crowding, anchorage, axial inclination of canine and incisors, midline discrepancies and left/right symmetry, also the vertical dimension. In general there were two methods of space closure, non-sliding mechanics and sliding mechanics. To achieve space closure with the teeth desired, we must planned the anchorage control strategies. Differential force system are an excellent means in anchorage control, where the M/F ratio of the anchor teeth must be stronger than the teeth which moved.

  19. 77 FR 17009 - Review of Federal Permit Conditions

    Science.gov (United States)

    2012-03-23

    ... Transportation Projects; 188 W. Northern Lights Blvd., Suite 600; Anchorage, AK 99503. Submit electronic comments... only be made if the contractual in- service date were reasonable in light of the complexity of the...

  20. HER-2 as a Progression Factor and Therapeutic Target in Breast Cancer

    National Research Council Canada - National Science Library

    1999-01-01

    ...). We had observed previously that upon reduction of llER-2 in MCF-7 cells by ribozyme-targeting estradiol lost its ability to induce anchorage- independent colony formation in soft agar of the tumor cell...

  1. The Role of EMMPRIN in Tumor Angiogenesis and Metastasis

    National Research Council Canada - National Science Library

    Marieb, Erica

    2002-01-01

    .... Using a soft agar assay to assess anchorage-independent growth, increased expression of EMMPRIN stimulated 10-fold and 5-fold increases respectively in the number of colonies formed by MDA-MB-436 and MCF-7...

  2. Efficacy of modified pendulum appliance for the correction of class II malocclusion: A clinical study

    OpenAIRE

    Monika Koul; Ayushi Singla; Anil Singla; Vivek Mahajan; Harupinder Singh Jaj; Priyanka Negi

    2017-01-01

    Introduction: The purpose of this prospective study was to analyze the efficiency of pendulum appliance for distalizing maxillary first molar while decreasing the anchorage loss by banding first and second premolar and making them one unit. Materials and Methods: The study group comprised of 20 patients (mean age 13 ± 2 years) who had skeletal Class I and Angle's Class II molar relation. Modified pendulum appliance was given to distalize maxillary first molar and to decrease the anchorage los...

  3. Targeting TMPRSS2 ERG in Prostate Cancer

    Science.gov (United States)

    2016-09-01

    understanding of ERG mediated oncogenesis. We used a novel method to measure gene expression in a high throughput format to screen shRNAs and small... transformation by anchorage independent growth in soft agar (months 13-24 – 75% completed) 1e. Bioinformatic analysis of results correlating gene expression...2c, measure effect on invasion using transwell invasion assay, EMT using immunofluorescence and immunoblotting, and transformation by anchorage

  4. Suspected Palytoxin Inhalation Exposures Associated with Zoanthid Corals in Aquarium Shops and Homes - Alaska, 2012-2014.

    Science.gov (United States)

    Hamade, Ali K; Deglin, Sandrine E; McLaughlin, Joe B; Deeds, Jonathan R; Handy, Sara M; Knolhoff, Ann M

    2015-08-14

    On August 12, 2014, an Anchorage hospital notified the Alaska Section of Epidemiology (SOE) that a middle-aged male resident of Anchorage (patient A) had arrived in the emergency department with possible palytoxin exposure. Patient A complained of a bitter metallic taste, fever, weakness, cough, and muscle pain 7-8 hours after introduction of live zoanthid coral into his home aquarium. Palytoxin, a potent toxin known to produce the reported effects, is contained in zoanthid marine corals.

  5. Possibility of space closure without initial alignment

    OpenAIRE

    Amit Jain; Saugat Ray; Rajat Mitra; S S Chopra

    2015-01-01

    Orthodontic space closure had always remained in focus due to complex biomechanics involved in almost all the treatment modalities. Although lot of efforts have been made from time to time to control the anchorage by complex wire bending or surgical methods like temporary anchorage devices (TAD′s), but all have some added inherent disadvantage. An effort has been made to do carry out orthodontic space closure without any complex archwire bending or any surgically assisted method including TAD...

  6. Suprabasin Is Hypomethylated and Associated with Metastasis in Salivary Adenoid Cystic Carcinoma

    OpenAIRE

    Shao, Chunbo; Tan, Marietta; Bishop, Justin A.; Liu, Jia; Bai, Weiliang; Gaykalova, Daria A.; Ogawa, Takenori; Vikani, Ami R.; Agrawal, Yuri; Li, Ryan J.; Kim, Myoung Sook; Westra, William H.; Sidransky, David; Califano, Joseph A.; Ha, Patrick K.

    2012-01-01

    Background Salivary gland adenoid cystic carcinoma (ACC) is a rare cancer, accounting for only 1% of all head and neck malignancies. ACC is well known for perineural invasion and distant metastasis, but its underlying molecular mechanisms of carcinogenesis are still unclear. Principal Findings Here, we show that a novel oncogenic candidate, suprabasin (SBSN), plays important roles in maintaining the anchorage-independent and anchorage-dependent cell proliferation in ACC by using SBSN shRNA st...

  7. Mini-Implants: New Possibilities in Interdisciplinary Treatment Approaches

    OpenAIRE

    Sebastian, Biju

    2014-01-01

    The introduction of mini-implants has broadened the range of tooth movements possible by fixed appliance therapy alone. The limits of fixed orthodontic treatment have become more a matter of facial appearance than anchorage. Many complex cases which would previously have required surgery or functional appliances can now be treated with fixed appliance therapy using mini-implants. A mutilated dentition case where mini-implants were used to provide anchorage for intrusion of molars and retract...

  8. Lingual biomechanics, case selection and success

    Directory of Open Access Journals (Sweden)

    Sanjay Labh

    2016-01-01

    Full Text Available Deeper understanding of lingual biomechanics is prerequisite for success with lingual appliance. The difference between labial and lingual force system must be understood and kept in mind during treatment planning, especially anchorage planning, and extraction decision-making. As point of application of force changes, it completely changes the force system in all planes. This article describes lingual biomechanics, anchorage planning, diagnostic considerations, treatment planning, and case selection criteria in lingual orthodontics.

  9. 33 CFR 110.230 - Puget Sound Area, Wash.

    Science.gov (United States)

    2010-07-01

    ...) Cap Sante Tug and Barge General Anchorage. The Cap Sante Tug and Barge General Anchorage includes all... approximately the northeast tip of Cap Sante; then southeast to 48°30′53″ N, 122°35′28″ W; then west southwest to 48°30′45″ N, 122°35′52″ W, approximately the south tip of Cap Sante; then north along the...

  10. Application of pre-stressed technology in the crossing construction of the China–Myanmar Gas Pipeline

    Directory of Open Access Journals (Sweden)

    Xuejun Wang

    2015-01-01

    Full Text Available Concrete structure is commonly used in the anchorages of a large cable-suspended pipeline crossing construction. With the increase of span and load, the stress on the concrete anchorages may rise rapidly. In case of traditional anchoring structure fixed by anchor rods, concrete cracking will occur, thereby reducing the anchorage life. To solve this problem, the pre-stressed structure was designed to effectively improve the efficiency of anchoring and reduce engineering cost. In the crossing construction of China–Myanmar Gas Pipeline, the pre-stressed technology was used to establish an effective pre-stressed anchoring system, which integrates the pre-stressed structures (e.g. tunnel anchorages in the anchors and the optimization measures (e.g. positioning mode, anchorage structure, concrete placement, pre-stressed, and medium injection, in line with the crossing structure and load features of this project. The system can delay the occurrence of concrete cracking and enhance the stress durability of the structure and anchoring efficiency. This technology has been successfully applied in the crossing construction of China–Myanmar Gas Pipeline, with good economic and social benefits, indicating that this technology is a new effective solution to the optimization of suspended pipeline anchorage structures, providing technical support for the development of pipeline crossing structure.

  11. Analisis parametrico de las variables que influyen en el comportamiento adherente de las armaduras pretesas en el hormigon

    Science.gov (United States)

    Arbelaez Jaramillo, Cesar Augusto

    Prestressed concrete technique through the use of prestressed reinforcement is extended in the precast concrete industry. This technique consists on casting a concrete element over a previously prestressed reinforcement, proceeding to release once the concrete has reached a determined strength so the prestressed stress introduced to the reinforcement be transmitted, by bond, to concrete. The bond behaviour of prestressed reinforcement includes two phenomena: prestress transmission from the reinforcement to concrete and anchorage of the reinforcement. This bond behaviour is characterized by mean of two lengths: transmission length and anchorage length. The good design of these lengths is a basic and fundamental aspect in the project of precast prestressed concrete elements to guaranty the appropriate transmission of prestress and to allow the anchorage of the reinforcement along the structural element service life. The influence of the parameters related to the concrete dosage on the transmission and anchorage lengths of prestressing strands have been analyzed. The ECADA test method has been applied. With this method the operations of transmission of prestress and anchorage of the reinforcement are sequentially done. The transmission and anchorage lengths are determined from the force control supported by the reinforcement testing series of specimens with different embedment lengths. The differentiation of the concepts of anchorage length without slips and with slips has been proposed. The relationship of the parameters of dosage with the bond stress and the registered slips during the processes of transmission and anchorage has been studied. Expressions to value the slips distribution of the reinforcement in the transmission zone and in the anchorage zone have been proposed. A study on the determination of the transmission length from the free reinforcement slip end has been done and the viability to experimentally determine the transmission length from the slips

  12. Determining Pull-Out Deformations by Means of an Online Photogrammetry Monitoring System

    Directory of Open Access Journals (Sweden)

    Emin Özgür Avşar

    2015-03-01

    Full Text Available Chemical anchorages are applied in many engineering implementations, particularly strengthening of reinforced concrete structures. During strengthening procedure; chemical anchorages should be tested, since they supply to transfer the load between existing construction elements and newly added elements. Therefore; the study of the quality of chemical anchorages is an important issue in construction materials science. In this context; the most important experiment is to determine the pull-out loads of embedded anchorage reinforcement by applying axial loads. In this study; it is aimed to determine the displacements of steel reinforcements, embedded into concrete by using chemical anchorages, while applying axial pulling loads. In order to determine the displacements and load - deformation graphs; starting conditions and every 10 bar pressure applied conditions of the steel reinforcements were captured by the cameras. The obtained images were evaluated by using photogrammetric software. Based on the photogrammetric post-processing results, the load - deformation graphs were plotted and the loads at loss of adhesion were determined

  13. Extracortical plate fixation with new plate inserts and cerclage wires for the treatment of periprosthetic hip fractures.

    Science.gov (United States)

    Bastian, Johannes D; Butscher, Andre; Bigolin, Gianni; Zumstein, Matthias A; Nötzli, Hubert P

    2014-03-01

    Fixation of periprosthetic hip fractures with intracortical anchorage might not be feasible in cases with bulky implants and/or poor bone stock. Rotational stability of new plate inserts with extracortical anchorage for cerclage fixation was measured and compared to the stability found using a standard technique in a biomechanical setup using a torsion testing machine. In a synthetic PUR bone model, transverse fractures were fixed distally using screws and proximally by wire cerclages attached to the plates using "new" (extracortical anchorage) or "standard" (intracortical anchorage) plate inserts. Time to fracture consolidation and complications were assessed in a consecutive series of 18 patients (18 female; mean age 81 years, range 55-92) with periprosthetic hip fractures (ten type B1, eight type C-Vancouver) treated with the new device between July 2003 and July 2010. The "new" device showed a higher rotational stability than the "standard" technique (p Fractures showed radiographic consolidation after 14 ± 5 weeks (mean ± SD) postoperatively in patients. Revision surgery was necessary in four patients, unrelated to the new technique. In periprosthetic hip fractures in which fixation with intracortical anchorage using conventional means might be difficult due to bulky revision stems and/or poor bone stock, the new device may be an addition to the range of existing implants.

  14. Pedicle Screw Fixation Study in Immature Porcine Spines to Improve Pullout Resistance during Animal Testing.

    Directory of Open Access Journals (Sweden)

    Sophie Le Cann

    Full Text Available The porcine model is frequently used during development and validation of new spinal devices, because of its likeness to the human spine. These spinal devices are frequently composed of pedicle screws with a reputation for stable fixation but which can suffer pullouts during preclinical implantation on young animals, leading to high morbidity. With a view to identifying the best choices to optimize pedicle screw fixation in the porcine model, this study evaluates ex vivo the impact of weight (age of the animal, the level of the vertebrae (lumbar or thoracic and the type of screw anchorage (mono- or bi-cortical on pedicle screw pullouts. Among the 80 pig vertebrae (90- and 140-day-old tested in this study, the average screw pullout forces ranged between 419.9N and 1341.2N. In addition, statistical differences were found between test groups, pointing out the influence of the three parameters stated above. We found that the the more caudally the screws are positioned (lumbar level, the greater their pullout resistance is, moreover, screw stability increases with the age, and finally, the screws implanted with a mono-cortical anchorage sustained lower pullout forces than those implanted with a bi-cortical anchorage. We conclude that the best anchorage can be obtained with older animals, using a lumbar fixation and long screws traversing the vertebra and inducing bi-cortical anchorage. In very young animals, pedicle screw fixations need to be bi-cortical and more numerous to prevent pullout.

  15. Pedicle Screw Fixation Study in Immature Porcine Spines to Improve Pullout Resistance during Animal Testing.

    Science.gov (United States)

    Le Cann, Sophie; Cachon, Thibaut; Viguier, Eric; Miladi, Lotfi; Odent, Thierry; Rossi, Jean-Marie; Chabrand, Patrick

    2015-01-01

    The porcine model is frequently used during development and validation of new spinal devices, because of its likeness to the human spine. These spinal devices are frequently composed of pedicle screws with a reputation for stable fixation but which can suffer pullouts during preclinical implantation on young animals, leading to high morbidity. With a view to identifying the best choices to optimize pedicle screw fixation in the porcine model, this study evaluates ex vivo the impact of weight (age) of the animal, the level of the vertebrae (lumbar or thoracic) and the type of screw anchorage (mono- or bi-cortical) on pedicle screw pullouts. Among the 80 pig vertebrae (90- and 140-day-old) tested in this study, the average screw pullout forces ranged between 419.9N and 1341.2N. In addition, statistical differences were found between test groups, pointing out the influence of the three parameters stated above. We found that the the more caudally the screws are positioned (lumbar level), the greater their pullout resistance is, moreover, screw stability increases with the age, and finally, the screws implanted with a mono-cortical anchorage sustained lower pullout forces than those implanted with a bi-cortical anchorage. We conclude that the best anchorage can be obtained with older animals, using a lumbar fixation and long screws traversing the vertebra and inducing bi-cortical anchorage. In very young animals, pedicle screw fixations need to be bi-cortical and more numerous to prevent pullout.

  16. Miniscrew-assisted customized lingual appliances for predictable treatment of skeletal Class II malocclusion with severe deep overbite and overjet.

    Science.gov (United States)

    Wang, Xue-Dong; Lei, Fei-Fei; Liu, Da-Wei; Zhang, Jie-Ni; Liu, Wei-Tao; Song, Yang; Zhou, Yan-Heng

    2017-07-01

    This report describes the use of miniscrew-assisted customized lingual fixed appliances in a patient with severe skeletal Class II malocclusion. The patient was a 12-year-old Chinese girl with the chief complaint of protrusive lips and anterior teeth. Her diagnosis included a skeletal Class II relationship with maxillary protrusion, a backward-rotated mandible, a full Angle Class II molar relationship, and severe deep overjet and overbite. Four premolars were extracted, and miniscrew anchorage was placed in the maxillary posterior lingual segment to provide maximum anchorage and to achieve vertical control of the intruding molars. The customized lingual fixed appliance and temporary anchorage devices created a smooth and invisible treatment progress, resulting ultimately in a well-aligned dentition with ideal intercuspation and a dramatically improved profile. The 3-year follow-up examination indicated that the excellent treatment outcome was stable. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  17. Transversely Compressed- and Restrained Shear Joints

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Hansen, Christian Skodborg

    2013-01-01

    Anchorage of FRP strengthening systems where the deformation perpendicular to the FRP material is restrained or a compressive force is applied on the strengthening, seems to provide ductility, increased utilization of the FRP and failure modes which can be controlled through the anchorage method....... This paper presents theoretical model which can predict the response of transversely compressed and restrained single- and double lap shear joints. The interface material model is based on a cohesive law in the shear-slip plane with a descending branch and a uniform frictional stress added due...... to the friction in the crack, emanating from the transverse pressure or restraint. The theoretical model is compared with experimental results from transversely compressed single- and double shear joints. Also theoretical predictions of a mechanical integrated sleeve-wedge anchorage load capacity are carried out...

  18. Versatile retraction mechanics: Implant assisted en-masse retraction with a boot loop

    Directory of Open Access Journals (Sweden)

    Pramod Philip

    2015-01-01

    Full Text Available The purpose of this paper is to explain the versatility offered by the use of arch wires with boot loops in retraction mechanics while taking direct anchorage from mini-screws. Materials and Methods: The materials include the mini screws placed at the appropriate location and retraction arches made of 0.019 X 0.025 SS with boot loops placed distal to the lateral incisors. Mini screw provides a stable anchorage for enmasse retraction of the anterior teeth with the help of a boot loop using sliding and/or loop mechanics. Results: The arch wires with boot loops have a definite advantage over the soldered/ crimpable hooks because of the versatility it offers during the process of retraction. Conclusion: An innovative approach combining the advantages of absolute anchorage using mini implants and a retraction arch with boot loop is presented here.

  19. A Mini-review on the Effect of Mini-implants on Contemporary Orthodontic Science.

    Science.gov (United States)

    Nosouhian, Saeid; Rismanchian, Mansour; Sabzian, Roya; Shadmehr, Elham; Badrian, Hamid; Davoudi, Amin

    2015-01-01

    The purpose of this literature review was to screen the valuable published articles regarding to the impacts of mini-implants on orthodontic science, briefly. The searching category was performed on the Pubmed using MeSH words such as "dental (mini) implants, orthodontic anchorage procedures, and orthodontic appliances." After preliminary sketch, they were grouped as follow: Those evaluating (a) common appliances for providing orthodontic anchorage, (b) biomechanical details of mini-implants and their insertion, (c) clinical application of mini-implants for orthognathic treatments, (d) limitations and possible complications. In conclusion, mini-implant evolved the orthodontic treatment plans and compromised the required orthognathic surgery. Malocclusion treatment and pure orthodontic or orthopedic movements in the three-dimensions have become recently possible by using mini-implant to provide skeletal anchorage.

  20. Use of the intraosseous screw for unilateral upper molar distalization and found well balanced occlusion

    Directory of Open Access Journals (Sweden)

    Buyukyilmaz Tamer

    2006-11-01

    Full Text Available Abstract Background The aim of this study was to present a temporary anchorage device with intraosseous screw for unilateral molar distalization to make a space for the impacted premolar and to found well balanced occlusion in a case. Case presentation A 13-year-old male who have an impacted premolar is presented with skeletal Class I and dental Class 2 relationship. The screw was placed and immediately loaded to distalize the left upper first and second molar. The average distalization time to achieve an overcorrected Class I molar relationship was 3.6 months. There was no change in overjet, overbite, or mandibular plane angle measurements. Mild protrusion (0.5 mm of the upper left central incisor was also recorded. Conclusion Immediately loaded intraosseous screw-supported anchorage unit was successful in achieving sufficient unilateral molar distalization without anchorage loss. This treatment procedure was an alternative treatment to the extraction therapy.

  1. Socket sclerosis--an obstacle for orthodontic space closure?

    Science.gov (United States)

    Baumgaertel, Sebastian

    2009-07-01

    Socket sclerosis is a rare reaction to tooth extraction resulting in high-density bone in the center of the alveolar process, where, under normal circumstances, cancellous bone is to be expected. In an adult orthodontic patient, routine extractions of the mandibular first permanent bicuspids were performed, resulting in socket sclerosis and unsuccessful orthodontic space closure. Orthodontic mini-implants were inserted to augment anchorage and aid in space closure. In the presence of socket sclerosis, conventional orthodontic mechanics failed to close the extraction spaces. However, with absolute anchorage in place, space closure occurred at a nearly normal rate. After treatment, no signs of socket sclerosis were discernible on the periapical radiographs. Socket sclerosis can be an obstacle for orthodontic space closure if traditional mechanics are employed. However, mini-implant-reinforced anchorage can lead to successful space closure, resulting in complete resolution of the sclerotic sites.

  2. Orthodontic Implants: Concepts for the Orthodontic Practitioner

    Directory of Open Access Journals (Sweden)

    Carlos Nelson Elias

    2012-01-01

    Full Text Available Orthodontic implants have become a reliable method in orthodontic practice for providing temporary additional anchorage. These devices are useful to control skeletal anchorage in less compliant patients or in cases where absolute anchorage is necessary. There are a great number of advantages in this new approach which include easy insertion, decreased patient discomfort, low price, immediate loading, reduced diameter, versatility in the forces to be used, ease of cleaning, and ease of removal. However, a proper management of the screws by the practitioner is necessary in order to increase the success rate of the technique. The purpose of this paper is to update practitioners on the current concepts of orthodontic implants and orthodontic mechanics.

  3. Versatile retraction mechanics: Implant assisted en-masse retraction with a boot loop.

    Science.gov (United States)

    Philip, Pramod; Jose, Nidhin Philip

    2015-03-01

    The purpose of this paper is to explain the versatility offered by the use of arch wires with boot loops in retraction mechanics while taking direct anchorage from mini-screws. The materials include the mini screws placed at the appropriate location and retraction arches made of 0.019 X 0.025 SS with boot loops placed distal to the lateral incisors. Mini screw provides a stable anchorage for enmasse retraction of the anterior teeth with the help of a boot loop using sliding and/or loop mechanics. The arch wires with boot loops have a definite advantage over the soldered/crimpable hooks because of the versatility it offers during the process of retraction. An innovative approach combining the advantages of absolute anchorage using mini implants and a retraction arch with boot loop is presented here.

  4. Stone cladding engineering

    CERN Document Server

    Sousa Camposinhos, Rui de

    2014-01-01

    This volume presents new methodologies for the design of dimension stone based on the concepts of structural design while preserving the excellence of stonemasonry practice in façade engineering. Straightforward formulae are provided for computing action on cladding, with special emphasis on the effect of seismic forces, including an extensive general methodology applied to non-structural elements. Based on the Load and Resistance Factor Design Format (LRDF), minimum slab thickness formulae are presented that take into consideration stress concentrations analysis based on the Finite Element Method (FEM) for the most commonly used modern anchorage systems. Calculation examples allow designers to solve several anchorage engineering problems in a detailed and objective manner, underlining the key parameters. The design of the anchorage metal parts, either in stainless steel or aluminum, is also presented.

  5. Effectiveness of en masse versus two-step retraction: a systematic review and meta-analysis.

    Science.gov (United States)

    Rizk, Mumen Z; Mohammed, Hisham; Ismael, Omar; Bearn, David R

    2018-01-05

    This review aims to compare the effectiveness of en masse and two-step retraction methods during orthodontic space closure regarding anchorage preservation and anterior segment retraction and to assess their effect on the duration of treatment and root resorption. An electronic search for potentially eligible randomized controlled trials and prospective controlled trials was performed in five electronic databases up to July 2017. The process of study selection, data extraction, and quality assessment was performed by two reviewers independently. A narrative review is presented in addition to a quantitative synthesis of the pooled results where possible. The Cochrane risk of bias tool and the Newcastle-Ottawa Scale were used for the methodological quality assessment of the included studies. Eight studies were included in the qualitative synthesis in this review. Four studies were included in the quantitative synthesis. En masse/miniscrew combination showed a statistically significant standard mean difference regarding anchorage preservation - 2.55 mm (95% CI - 2.99 to - 2.11) and the amount of upper incisor retraction - 0.38 mm (95% CI - 0.70 to - 0.06) when compared to a two-step/conventional anchorage combination. Qualitative synthesis suggested that en masse retraction requires less time than two-step retraction with no difference in the amount of root resorption. Both en masse and two-step retraction methods are effective during the space closure phase. The en masse/miniscrew combination is superior to the two-step/conventional anchorage combination with regard to anchorage preservation and amount of retraction. Limited evidence suggests that anchorage reinforcement with a headgear produces similar results with both retraction methods. Limited evidence also suggests that en masse retraction may require less time and that no significant differences exist in the amount of root resorption between the two methods.

  6. Understanding the Impact of Root Morphology on Overturning Mechanisms: A Modelling Approach

    Science.gov (United States)

    Fourcaud, Thierry; Ji, Jin-Nan; Zhang, Zhi-Qiang; Stokes, Alexia

    2008-01-01

    Background and Aims The Finite Element Method (FEM) has been used in recent years to simulate overturning processes in trees. This study aimed at using FEM to determine the role of individual roots in tree anchorage with regard to different rooting patterns, and to estimate stress distribution in the soil and roots during overturning. Methods The FEM was used to carry out 2-D simulations of tree uprooting in saturated soft clay and loamy sand-like soil. The anchorage model consisted of a root system embedded in a soil block. Two root patterns were used and individual roots removed to determine their contribution to anchorage. Key Results In clay-like soil the size of the root–soil plate formed during overturning was defined by the longest roots. Consequently, all other roots localized within this plate had no influence on anchorage strength. In sand-like soil, removing individual root elements altered anchorage resistance. This result was due to a modification of the shape and size of the root–soil plate, as well as the location of the rotation axis. The tap root and deeper roots had more influence on overturning resistance in sand-like soil compared with clay-like soil. Mechanical stresses were higher in the most superficial roots and also in leeward roots in sand-like soil. The relative difference in stresses between the upper and lower sides of lateral roots was sensitive to root insertion angle. Assuming that root eccentricity is a response to mechanical stresses, these results explain why eccentricity differs depending on root architecture. Conclusions A simple 2-D Finite Element model was developed to better understand the mechanisms involved during tree overturning. It has been shown how root system morphology and soil mechanical properties can modify the shape of the root plate slip surface as well as the position of the rotation axis, which are major components of tree anchorage. PMID:17942593

  7. Effectiveness of en masse versus two-step retraction: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Mumen Z. Rizk

    2018-01-01

    Full Text Available Abstract Background This review aims to compare the effectiveness of en masse and two-step retraction methods during orthodontic space closure regarding anchorage preservation and anterior segment retraction and to assess their effect on the duration of treatment and root resorption. Methods An electronic search for potentially eligible randomized controlled trials and prospective controlled trials was performed in five electronic databases up to July 2017. The process of study selection, data extraction, and quality assessment was performed by two reviewers independently. A narrative review is presented in addition to a quantitative synthesis of the pooled results where possible. The Cochrane risk of bias tool and the Newcastle-Ottawa Scale were used for the methodological quality assessment of the included studies. Results Eight studies were included in the qualitative synthesis in this review. Four studies were included in the quantitative synthesis. En masse/miniscrew combination showed a statistically significant standard mean difference regarding anchorage preservation − 2.55 mm (95% CI − 2.99 to − 2.11 and the amount of upper incisor retraction − 0.38 mm (95% CI − 0.70 to − 0.06 when compared to a two-step/conventional anchorage combination. Qualitative synthesis suggested that en masse retraction requires less time than two-step retraction with no difference in the amount of root resorption. Conclusions Both en masse and two-step retraction methods are effective during the space closure phase. The en masse/miniscrew combination is superior to the two-step/conventional anchorage combination with regard to anchorage preservation and amount of retraction. Limited evidence suggests that anchorage reinforcement with a headgear produces similar results with both retraction methods. Limited evidence also suggests that en masse retraction may require less time and that no significant differences exist in the amount of root

  8. Calculation of shear strength of prestressed hollow core slabs by use of plastic theory

    DEFF Research Database (Denmark)

    Hoang, Linh Cao; Jørgensen, Henrik Brøner; Nielsen, Mogens Peter

    2014-01-01

    This paper deals with calculations of the shear capacity of precast, prestressed hollow core slabs. Such slabs are often used as floor systems in Building structures. A common way to produce hollow core slabs is to use the extrusion technique where long strips of slabs are extruded and thereafter...... saw-cut into units with the desirable length. For this reason, hollow core slabs are usually not shear reinforced and anchorage of the prestressing strands has to be established by bond. Hollow core slabs may therefore be more critical to shear and Anchorage failure than ordinary two-way spanning...... reinforced concrete slabs....

  9. Modified sliding mechanics in extraction cases with a bidimensional approach.

    Science.gov (United States)

    Giancotti, Aldo; Greco, Mario

    2010-01-01

    To illustrate a modified archwire during space closure with anterior anchorage in Bidimensional Tecnique. The archwire used was a .018x.025 SS on the anterior teeth and .018 SS on the lateral and posterior teeth in order to maintain anterior anchorage using torque and uprighting springs as showed in Bidmensional Technique but exerting lighter forces (150 g). The double section archwire resulted to be an effective alternative option to optimize the lateral and posterior sliding mechanics with controlled tipping and by the application of lighter forces. Copyright © 2010 Società Italiana di Ortodonzia SIDO. Published by Elsevier Srl. All rights reserved.

  10. A Clinical Evaluation of Three Force Delivery Systems in Stage II of the Begg Technique

    Directory of Open Access Journals (Sweden)

    Vincy Antony Margaret

    2013-01-01

    Materials and methods: The present study was designed to compare the rates of retraction and anchorage loss between elastics, elastomeric chains and nickel-titanium (NiTi closed coil springs, using a continuous archwire system with the Begg light wire differential force technique. Results: The rate of canine retraction was faster by 0.6 mm per month with the NiTi closed coil spring compared to elastics and elastomeric chains. The NiTi closed coil springs produced more rapid rate of canine retraction but they also produced the greatest amount of anchorage loss.

  11. State of the art of miniscrew implants: an interview with Sebastian Baumgaertel. Interviewed by Robert P. Scholz.

    Science.gov (United States)

    Baumgaertel, Sebastian

    2009-08-01

    Dr Baumgaertel is an assistant clinical professor at Case Western Reserve University in Cleveland, Ohio, and director of the subspecialty clinic for skeletal anchorage. He also maintains an active private orthodontic practice. He has lectured nationally and internationally on orthodontic mini-implants and cone-beam computed tomography. He has published many scientific articles and is coeditor of the textbook Mini-Implants in Orthodontics-Innovative Anchorage Concepts. He serves as a member of the editorial review board of the AJO-DO and acts as ad-hoc reviewer for several other scientific dental journals.

  12. Possibility of space closure without initial alignment

    Directory of Open Access Journals (Sweden)

    Amit Jain

    2015-01-01

    Full Text Available Orthodontic space closure had always remained in focus due to complex biomechanics involved in almost all the treatment modalities. Although lot of efforts have been made from time to time to control the anchorage by complex wire bending or surgical methods like temporary anchorage devices (TAD′s, but all have some added inherent disadvantage. An effort has been made to do carry out orthodontic space closure without any complex archwire bending or any surgically assisted method including TAD′s.

  13. 33 CFR 110.87 - Henderson Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Henderson Harbor, N.Y. 110.87... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.87 Henderson Harbor, N.Y. (a) Area A. The area in the... latitude 43°51′08.8″ N, longitude 76°12′08.9″ W, thence to latitude 43°51′09.0″ N, longitude 76°12′19.0″ W...

  14. Controlled canine retraction using orthodontic mini-implants coupled with bondable powerarms.

    Science.gov (United States)

    Cousley, Richard

    2015-01-01

    Many patients present with a substantial amount of anterior dental crowding, necessitating canine retraction prior to incisor alignment. Conventional biomechanics typically requires anchorage reinforcement and risks distal tipping of the canine crown and a delay before incisor alignment. However, it is now possible to produce controlled canine retraction without anchorage loss, even with narrow, flexible archwires in situ. This enables simultaneous alignment of displaced incisors. This technique involves a combination of orthodontic mini-implants (OMIs) and a powerarm bonded directly on either the labial or palatal surface of the target tooth, as described in this paper.

  15. Mini-implants: new possibilities in interdisciplinary treatment approaches.

    Science.gov (United States)

    Sebastian, Biju

    2014-01-01

    The introduction of mini-implants has broadened the range of tooth movements possible by fixed appliance therapy alone. The limits of fixed orthodontic treatment have become more a matter of facial appearance than anchorage. Many complex cases which would previously have required surgery or functional appliances can now be treated with fixed appliance therapy using mini-implants. A mutilated dentition case where mini-implants were used to provide anchorage for intrusion of molars and retraction of anterior teeth is reported here to illustrate this point.

  16. Mini-implant-supported Molar Distalization

    Directory of Open Access Journals (Sweden)

    Amit Goyal

    2012-01-01

    Full Text Available Temporary anchorage devices popularly called mini-implants or miniscrews are the latest addition to an orthodontist′s armamentarium. The following case report describes the treatment of a 16-year-old girl with a pleasant profile, moderate crowding and Angle′s Class II molar relationship. Maxillary molar distalization was planned and mini-implants were used to preserve the anterior anchorage. After 13 months of treatment, Class I molar and canine relation was achieved bilaterally and there was no anterior proclination. Thus, mini-implants provide a viable option to the clinician to carry out difficult tooth movements without any side effects.

  17. Asymmetry a challenge for orthodontists

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

      Asymmetry is considered a challenge and often the reason for which the optimal result cannot be obtained. The explanations are many. Only rarely, the cause of the asymmetry is localized and camouflage is frequently resulting in the development a different type of asymmetry occurring in all thre...... the required tooth displacements can be generated. In order to control the interaction between the force systems developed in the three planes of space, the appliances should commonly be segmented. Anchorage problems can occasionally only be solved by means of skeletal anchorage....

  18. Mini-Implants: New Possibilities in Interdisciplinary Treatment Approaches

    Directory of Open Access Journals (Sweden)

    Biju Sebastian

    2014-01-01

    Full Text Available The introduction of mini-implants has broadened the range of tooth movements possible by fixed appliance therapy alone. The limits of fixed orthodontic treatment have become more a matter of facial appearance than anchorage. Many complex cases which would previously have required surgery or functional appliances can now be treated with fixed appliance therapy using mini-implants. A mutilated dentition case where mini-implants were used to provide anchorage for intrusion of molars and retraction of anterior teeth is reported here to illustrate this point.

  19. Versatile retraction mechanics: Implant assisted en-masse retraction with a boot loop

    OpenAIRE

    Philip, Pramod; Jose, Nidhin Philip

    2015-01-01

    The purpose of this paper is to explain the versatility offered by the use of arch wires with boot loops in retraction mechanics while taking direct anchorage from mini-screws. Materials and Methods: The materials include the mini screws placed at the appropriate location and retraction arches made of 0.019 X 0.025 SS with boot loops placed distal to the lateral incisors. Mini screw provides a stable anchorage for enmasse retraction of the anterior teeth with the help of a boot loop using sli...

  20. Experimental investigations and seismic analysis for benchmark study of 1000 MW WWER type units (water-cooled and moderated reactor) nuclear power plant Kozloduy. Final report from 1 November 1994 - 31 October 1995

    International Nuclear Information System (INIS)

    Sachanski, S.

    1996-01-01

    This final report summarizes the research carried out and the results obtained presented in previous progress reports. In includes the description of the research carried out, namely, definition of terms and references, criteria, design parameters and methods of analysis; development of 3-dimensional and 2-dimensional mathematical models for diesel generator stations concerning seismic analyses; supports and anchorages analyses and seismic capacity estimation for main components of the cooling system; methodology for verification of component anchorages; conclusions drawn concerning the seismic safety of Kozloduy NPP

  1. Calculation of shear strength of prestressed hollow core slabs by use of plastic theory

    DEFF Research Database (Denmark)

    Hoang, Linh Cao; Jørgensen, H.G.; Nielsen, Mogens Peter

    2014-01-01

    Th is paper deals with calculations of the shear capacity of precast, prestressed hollow core slabs. Such slabs are often used as floor systems in building structures. A common way to produce hollow core slabs is to use the extrusion technique where long strips of slabs are extruded and thereafter...... saw-cut into units with the desirable length. For this reason, hollow core slabs are usually not shear reinforced and anchorage of the prestressing strands has to be established by bond. Hollow core slabs may therefore be more critical to shear and anchorage failure than ordinary two-way spanning...... reinforced concrete slabs....

  2. 78 FR 13207 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2013-02-26

    ...--Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority Relating to the... Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and Movement of... north of Cuba. On February 26, 2004, by Proclamation 7757, the national emergency was extended and its...

  3. 76 FR 11071 - Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority...

    Science.gov (United States)

    2011-02-28

    ...--Continuation of the National Emergency With Respect to Cuba and of the Emergency Authority Relating to the... Respect to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and Movement of... north of Cuba. On February 26, 2004, by Proclamation 7757, the national emergency was extended and its...

  4. 75 FR 8791 - Continuation of the National Emergency Relating to Cuba and of the Emergency Authority Relating...

    Science.gov (United States)

    2010-02-25

    ... to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and Movement of... February 23, 2010 Continuation of the National Emergency Relating to Cuba and of the Emergency Authority....-registered civilian aircraft in international airspace north of Cuba. On February 26, 2004, by Proclamation...

  5. K.S. Micro‑Implant Placement Guide

    African Journals Online (AJOL)

    immediately and rapid healing. A one of the greatest concerns with orthodontic mini-implants is a risk of ... [2] Even though, periodontal structures can heal after being injured by temporary orthodontic anchorage devices,[3] ... apical to the alveolar crest). After vertical height is determined, continues vertical loop made until ...

  6. 78 FR 20388 - Notice of Receipt of Petition for Decision that Nonconforming 2007 Ford Escape Multi-Purpose...

    Science.gov (United States)

    2013-04-04

    ... Protection, 216 Roof Crush Resistance, 219 Windshield Zone Intrusion, 225 Child Restraint Anchorages, 301... . Follow the online instructions for submitting comments. Mail: Docket Management Facility: U.S. Department... online instructions for accessing the dockets. The docket ID number and title of this notice are shown at...

  7. epoxy isocapnolactone and 8- hydroxyisocapnolactone-2'3'-diol ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-15

    Sep 15, 2009 ... Suspension cell line, CEM-SS (human T-lymphoblastic leukemia) was obtained from the National Cancer Institute, Frederick, Mary- land, USA. Anchorage dependent cell lines, HeLa (cervical carci- noma), HT29 (colon carcinoma), HepG2 (liver carcinoma) and. Chang (transform liver cell) were obtained ...

  8. University of Texas MD Anderson: Phenotypic Examination of PIK3CA Allelic Series using In Vitro/In Vivo Sensor Platforms | Office of Cancer Genomics

    Science.gov (United States)

    The CTD2 Center at the University of Texas MD Anderson Cancer Center utilized an established and operational MCF10A normal breast epithelial cell model to assess the ability of candidate driver aberrations to promote cell grow in anchorage-independent conditions (soft agar assay) and proliferate in the absence of insulin and epidermal growth factor (EGF).

  9. 75 FR 77572 - Proposed Revision of Class E Airspace; Platinum AK

    Science.gov (United States)

    2010-12-13

    ... proposes to revise Class E airspace at Platinum AK. The creation of a new Standard Instrument Approach... Platinum Airport, in Platinum, AK, to accommodate the creation of a new SIAP at the Platinum Airport. This... the Platinum Airport. Issued in Anchorage, AK, on November 17, 2010. Michael A. Tarr, Alaska Flight...

  10. 76 FR 49388 - Proposed Establishment of Class E Airspace; Tatitlek, AK

    Science.gov (United States)

    2011-08-10

    ... action proposes to establish Class E airspace at Tatitlek, AK. The creation of a standard instrument... within a 6.4-mile radius of the Tatitlek Airport, AK and within 2 miles southwest and 3.4 miles northeast... within a 60-mile radius of the Tatitlek Airport, AK. Issued in Anchorage, AK, on July 26, 2011. Michael A...

  11. 75 FR 34393 - Proposed Establishment of Class E Airspace; Port Clarence, AK

    Science.gov (United States)

    2010-06-17

    ... Regulations (14 CFR) part 71 by establishing Class E airspace at Port Clarence, AK, to accommodate a new.../FIR (PAZA) boundary. Issued in Anchorage, AK, on May 28, 2010. Michael A. Tarr, Manager, Alaska Flight...-0354; Airspace Docket No. 10-AAL-10] Proposed Establishment of Class E Airspace; Port Clarence, AK...

  12. 75 FR 62460 - Revocation and Establishment of Class E Airspace; Northeast Alaska, AK

    Science.gov (United States)

    2010-10-12

    .... The recent removal of a Colored Federal Airway near Kaktovik, AK, duplication of controlled airspace... Mentasta Lake/Mountains Area, AK [Removed] Issued in Anchorage, AK, on September 29, 2010. Michael A. Tarr..., AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action...

  13. 33 CFR 334.870 - San Diego Harbor, Calif.; restricted area.

    Science.gov (United States)

    2010-07-01

    ... shall not be open to swimming, fishing, mooring or anchorage. (ii) Transit will be allowed through the... introduction of external magnetic field sources within the area. (ii) Craft of any size shall not be excluded... exceeding 30 minutes. (iii) No craft of any size shall lay-to or anchor within the area except on prior...

  14. 33 CFR 334.865 - Naval Air Station North Island, San Diego, California, restricted area.

    Science.gov (United States)

    2010-07-01

    ... shall not be open to swimming, fishing, water-skiing, mooring or anchorage. (2) Dragging, seining, other fishing operations, and other activities not under the direction of the United States, which might foul... vessel or craft of any size shall lie-to or anchor in the restricted area at any time other than a vessel...

  15. 78 FR 53189 - Dorel Juvenile Group, Denial of Petition for Decision of Inconsequential Noncompliance

    Science.gov (United States)

    2013-08-28

    ... on the road. The vehicle belts and lower anchorage belts were routed through the forward-facing belt... is one of the DJG models included in this petition. Based on CU observations, the rear-facing belt... Federal Register (77 FR 2776). NHTSA received one comment from Consumers Union (CU). To view the petition...

  16. Auto Safety

    Science.gov (United States)

    ... booster seat. All kids under 13 years of age should always ride in the back seat, and in the middle of the back seat whenever possible. All passengers must have their seatbelts buckled. The LATCH System Since September 2002, most new vehicles have safety seat anchorage points and most ...

  17. Instructions for collecting and dispatch of living tropical Lemnaceae

    NARCIS (Netherlands)

    Landolt, E.

    1957-01-01

    1. Occurrence.--Lemnaceae may occur in stagnant or sluggish streaming waters, specially in ditches, pools, streamlets, inundated rice-fields, etc. They are also found in all other waters in which larger swamp plants offer anchorage to the tiny Lemnaceae. They can be expected between stands of

  18. Report of a Class I bimaxillary dental protrusion case with extraction of first premolars treated with Clarity™ SL MBT appliances

    Directory of Open Access Journals (Sweden)

    Hugo Trevisi

    2013-01-01

    Full Text Available Bimaxillary protrusion cases are common in orthodontic practice. For the best facial outcome, the biomechanics can often be challenging. A class I bimaxillary protrusion case is presented below illustrating the careful application of extractions and bracket prescription. The case highlights how self-ligating brackets and high precision bracket positioning can reduce the need for additional anchorage.

  19. 77 FR 47864 - Ocean Energy Safety Advisory Committee (OESC); Notice of Meeting

    Science.gov (United States)

    2012-08-10

    ... DEPARTMENT OF THE INTERIOR Bureau of Safety and Environmental Enforcement Ocean Energy Safety Advisory Committee (OESC); Notice of Meeting AGENCY: Bureau of Safety and Environmental Enforcement (BSEE), Interior. ACTION: Notice of meeting. SUMMARY: OESC will meet at the Anchorage Marriott Downtown Hotel in...

  20. Wood energy for residential heating in Alaska: current conditions, attitudes, and expected use

    Science.gov (United States)

    David L. Nicholls; Allen M. Brackley; Valerie. Barber

    2010-01-01

    This study considered three aspects of residential wood energy use in Alaska: current conditions and fuel consumption, knowledge and attitudes, and future use and conditions. We found that heating oil was the primary fuel for home heating in southeast and interior Alaska, whereas natural gas was used most often in south-central Alaska (Anchorage). Firewood heating...

  1. AcEST: DK956353 [AcEST

    Lifescience Database Archive (English)

    Full Text Available -agglutinin anchorage subunit OS=Saccharom... 30 7.7 sp|P36304|POLR_KYMVJ RNA replicase polyprotein OS=Ken...nedya yello... 30 9.9 sp|A6T015|LEUC_JANMA 3-isopropylmalate dehydratase large subu

  2. Is the pull-out force of the Meniscus Arrow in bone affected by the inward curling of the barbs during biodegradation? An in vitro study

    NARCIS (Netherlands)

    Wouters, Diederick B.; Burgerhof, Johannes G. M.; de Hosson, Jeff T. M.; Bos, Rudolf R. M.

    Background: Inward curling of the barbs of Meniscus Arrows during degradation was observed in a previous study, in which swelling, distention, and water uptake by Meniscus Arrows was evaluated. This change of configuration could have consequences with respect to anchorage capacity in bone.

  3. Histomorphometric and removal torque analysis for TiO2-blasted titanium implants. An experimental study on dogs

    DEFF Research Database (Denmark)

    Gotfredsen, K; Nimb, L; Hjörting-Hansen, E

    1992-01-01

    The aim of the present study was to compare the anchorage of TiO2-blasted screw and cylindrical implants with conventionally used machine-produced screw and cylindrical implants inserted immediately in extraction sockets on dogs. 6 adult mongrel dogs had 3rd and 4th mandibular premolars extracted...

  4. 33 CFR 165.504 - Newport News Shipbuilding and Dry Dock Company Shipyard, James River, Newport News, Va.

    Science.gov (United States)

    2010-07-01

    ..., thence along the shoreline to the point of beginning. (c) Special Regulations. (1) Section 165.33 (a), (e... encompassed by a line beginning at the intersection of the shoreline with the northernmost property line of... the shoreline to the point of beginning. (b) Security zone anchorage. The following is a security zone...

  5. The measurement of un-bonded tendon loads in PCPV and primary containment buildings

    International Nuclear Information System (INIS)

    Irving, Jim; Hinley, Malcom S.; McCluskey, D.

    1997-01-01

    This paper describes work undertaken as part of a study conducted for the Licensees of all commercial nuclear generating stations in the United Kingdom. The scope included researching the records of prestressing tendon load measurements held by the Licensees which encompassed 18 prestressed concrete pressure vessels (PCPV) for gas cooled reactors and one primary containment for PWR; the historical record contains more than 300 reactor-years of data. The main purpose of the study was to assess the validity of specified calibration and measurement techniques used by the Licensees or their contractors to establish jacking and residual anchorage loads in the post construction period. This included existing lift-off measurement techniques such as feeler gauge insertion and displacement transducer systems allied to graphical analysis of jack load versus displacement to determine the residual anchorage load. The second stage was to assess the designer's assumptions regarding long term creep and relaxation effects in the light of all available load checks since construction to determine whether the original design was adversely affected as a result of the current assessment of tendon load distributions. The paper includes summaries of the results of the assessment of historical load check data, load measurement methods and derived residual anchorage loads. Conclusions are made regarding the validity of design assumptions for anchorage and residual tendon loads and their implications for future load measurements

  6. 76 FR 11978 - Proposed Amendment of Federal Airways; Alaska

    Science.gov (United States)

    2011-03-04

    ... Federal airways in Alaska. Due to construction of wind turbines on Fire Island, AK, the Anchorage VOR is...; Biorka Island, AK; to Sandspit, BC. To Victoria, BC, Canada. The airspace within Canada is excluded. V... Landing, YT, Canada, NDB, excluding the portion which lies over Canadian territory. * * * * * Paragraph...

  7. 78 FR 42757 - Marine Mammals; File No. 17411

    Science.gov (United States)

    2013-07-17

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XC541 Marine Mammals; File No. 17411 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... permit has been issued to Dr. Jennifer Burns, University of Alaska Anchorage, Biology Department...

  8. Reinforced concrete T-beams externally prestressed with unbonded carbon fiber-reinforced polymer tendons

    DEFF Research Database (Denmark)

    Bennitz, Anders; Nilimaa, Jonny; Täljsten, Björn

    2012-01-01

    This study describes a series of experiments examining the behavior of seven beams prestressed with unbonded external carbon fiberreinforced polymer (CFRP) tendons anchored using a newly developed anchorage and post-tensioning system. The effects of varying the initial tendon depth, prestressing...

  9. A group of 20 stone anchors from the waters of Dwarka, on the Gujarat Coast, India

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.; Sundaresh; Tripati, S.; Gudigar, P.; Vora, K.H.; Bandodkar, S.N.

    suggesting an anchorage. Twenty stone anchors of three types located in a submerged channel on the southern side of the site. The grapnel type of anchor is associated with Indo-Arab trade between the 8th and 16th centuries AD. The triangular or composite...

  10. 33 CFR 110.140 - Buzzards Bay, Nantucket Sound, and adjacent waters, Mass.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buzzards Bay, Nantucket Sound, and adjacent waters, Mass. 110.140 Section 110.140 Navigation and Navigable Waters COAST GUARD..., Nantucket Sound, and adjacent waters, Mass. (a) New Bedford Outer Harbor—(1) Anchorage A. West of Sconticut...

  11. Un error en los calculos matematicos destroza el acelerador de particulas del CERN

    CERN Multimedia

    Cernuda, Olalla

    2007-01-01

    The most famous particle accelerator in the world, who is at CERN, has suffered a catastrophic damage after a great explosion took place in its depths. This explosion has an absolutely scientific explanation: a mathematical mistake in the design of the anchorages of great magnets. (1 page)

  12. 7 CFR Exhibit B to Subpart A of... - Requirements for Modular/Panelized Housing Units

    Science.gov (United States)

    2010-01-01

    ..., log wall houses, trussed roof rafters or floor trusses; open panel walls, and other types that can be... the accepted drawings and description of materials before the unit has been set on the foundation. 5.... Foundation and/or Basement Plan. This plan shall include anchorage details, exterior and interior dimensions...

  13. Effect of realistic vehicle seats, cushion length, and lap belt geometry on child ATD kinematics.

    Science.gov (United States)

    2011-12-01

    This series of sled tests examined the effect of using real vehicle seats on child ATD performance. Cushion length was varied from production length of 450 mm to a shorter length of 350 mm. Lap belt geometry was set to rear, mid, and forward anchorag...

  14. Twin - Arch technique. Revival of the "edgewise -Technique"?

    Directory of Open Access Journals (Sweden)

    Jacob Karp

    2012-01-01

    The SNB – Bracket brings a new dimension into the orthodontic world which is most apparent in extraction cases. Its Teflon – like material has a very low friction coefficient thus, reducing the treatment time considerably. Through the use of low dimensioned arch wires, the Twin – Arch Technique becomes a Light – wire system and simultaneously provides good anchorage and torque control.

  15. Untreated surgical conditions in Malawi: A randomised cross ...

    African Journals Online (AJOL)

    Lilongwe Campus, College of Medicine, University of Malawi, Lilongwe, Malawi. 3. Institute of ... Department of Obstetrics and Gynaecology, Alaska Native Medical Center, Anchorage, Alaska, USA. 8. College of ... This electronic tablet based questionnaire tool included general information and a dual personalised head.

  16. 75 FR 7517 - Notice of Intent To Prepare an Amendment to the Ring of Fire Resource Management Plan for the...

    Science.gov (United States)

    2010-02-19

    ... Recreation Management Area in Anchorage, Alaska. The site is currently managed under the 1988 Management Plan... environmental education, and optimizing outcome-focused management for recreation planning. The plan amendment... Special Recreation Management Area designated by the 1985 Recreation Action Plan; Develop a Special...

  17. Red alder kitchen cabinets—How does application of commercial stains influence customer choice?

    Science.gov (United States)

    David Nicholls; Joseph. Roos

    2007-01-01

    A better understanding of consumer reaction and preferences for red alder (Alnus rubra Bong.) secondary products will help Alaska producers in entering new markets. In this study, red alder kitchen cabinets were commercially stained to six different levels and displayed at home shows in Portland, Oregon, and Anchorage, Alaska. The stains simulated...

  18. Keeping Alaskan Tradition Alive: Building Relationships in the Curriculum

    Science.gov (United States)

    Hughes, Eileen; Forbes, Sue

    2005-01-01

    This article reviews varied types of relationships that were formed when a kindergarten class embarked on a study of the Native Alaskan art of carving. The public school kindergarten classroom, located in Anchorage, Alaska, drew from a community with a high population of Hispanic, African American, and Native Alaskan families with different…

  19. Animal experiment of periodontal tissue remodeling in application of ...

    African Journals Online (AJOL)

    In addition, the periodontal tissue on the buccal and the lingual sides also remodeled. In conclusion, the incisor teeth were not only intruded vertically but also showed rotation of the crown towards the labial side and the root towards the palatal side, by using mini-implants as anchorage. Besides, if the force applied was ...

  20. Animal experiment of periodontal tissue remodeling in application of ...

    African Journals Online (AJOL)

    user

    2011-02-21

    Feb 21, 2011 ... In addition, the periodontal tissue on the buccal and the lingual sides also remodeled. In conclusion, the incisor teeth were not only intruded vertically but also showed rotation of the crown towards the labial side and the root towards the palatal side, by using mini-implants as anchorage. Besides, if the force ...

  1. 30 CFR 902.10 - State regulatory program approval.

    Science.gov (United States)

    2010-07-01

    ... Mining and Water Management, 3601 C Street, Suite 800, Anchorage, AK 99503-5925, Telephone: (907) 762... Section 902.10 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE ALASKA § 902.10 State...

  2. 'Through a Glass Darkly': Assessing the 'New' War Against ...

    African Journals Online (AJOL)

    submits that while the legal and institutional anchorages of the war offer a good point of departure, they remain grossly inadequate. This largely explains why the war has been underproductive and caught in a deepening crisis of legitimacy. What is required is the nourishing and re-envisioning of such frameworks, coupled

  3. Exterior beam-column joint study with non-conventional ...

    Indian Academy of Sciences (India)

    Aboutaha (2003) reported that the use of straight-headed bars in the exterior beam-column joint for cyclic response were very effective in relocating potential plastic regions. Murty et al (2003) reported that the ACI standard hooks for anchorage of the longitudinal beam bar with hairclip- type transverse joint reinforcement ...

  4. 78 FR 8110 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-02-05

    ... will be held at the Hilton Hotel, Birch/Willow room, 500 West 3rd Avenue, Anchorage, AK. Council.../ . Although non-emergency issues not contained in this agenda may come before this group for discussion, those issues may not be the subject of formal action during these meetings. Action will be restricted to those...

  5. 78 FR 16660 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2013-03-18

    .... ADDRESSES: The meeting will be held at the Anchorage Hilton Hotel, Dillingham/Katmai Room, 500 West 3rd.../npfmc/ . Although non-emergency issues not contained in this agenda may come before this group for...-Stevens Act), those issues may not be the subject of formal action during this meeting. Actions will be...

  6. Documentation for Calculations of Standard Fire Resistance of Slabs and Walls of Concrete with Expanded Clay Aggregate

    DEFF Research Database (Denmark)

    Hertz, Kristian Dahl

    that the methods are applicable for slabs and walls of light weight aggregate concrete. It is shown that the temperatures for standard fire exposed cross sections can be calculated, that the ultimate moment capacity can be calculated for slabs, and that the anchorage capacity and the shear tension capacity can...... the transient strains into account....

  7. Comparison of different surface modifications for titanium implants installed into the goat iliac crest.

    NARCIS (Netherlands)

    Oirschot, B.A.J.A. van; Meijer, G.J.; Bronkhorst, E.M.; Narhi, T.; Jansen, J.A.; Beucken, J.J.J.P van den

    2016-01-01

    OBJECTIVES: This in vivo study with implants installed in the goat iliac crest was performed to determine whether the biological and mechanical properties of the bone-to-implant interface are influenced by (i) the type of implant anchorage (i.e., mono- vs. bicortical placement), and (ii) the

  8. 24 CFR 3285.405 - Severe wind zones.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Severe wind zones. 3285.405 Section... DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Anchorage Against Wind § 3285.405 Severe wind zones. When any part of a home is installed within 1,500 feet of a coastline in Wind Zones II or III, the...

  9. Effect of prostaglandin E1 versus corticotomy on orthodontic tooth movement: an in vivo study.

    Science.gov (United States)

    Rajasekaran, U B; Krishna Nayak, U S

    2014-01-01

    The aim of the present study is to compare the effect of corticotomy versus prostaglandin E1 injection in human subjects on rate of tooth movement, anchorage loss and their effect on crest bone height and root length. Clinical interventional study. Split mouth design was used. Study was done on 32 regular orthodontic patients. A volume of 100 mcg of prostaglandin E1 was injected on the right side once in 2 weeks and on the left side corticotomy was performed, and canine retraction was started on both sides simultaneously. The rate of space closure and anchorage loss was assessed with casts. The root length and crestal bone height changes were assed with IOPAs. The comparison of rate of tooth movement, anchorage loss, crestal bone height and root length changes between the sides were statistically analyzed using paired t-test. The average rate of space closure on right side was 0.36 mm/week with a standard deviation of 0.05 mm/week and on the left side average rate of space closure was 0.40 mm/week with a standard deviation of 0.04 mm/week. The difference between the rate of closure between the right side and left where found to be statistically significant (P=0.003). The anchorage loss, the crestal bone height changes and root length changes were not statistically significant. The rate of tooth movement was significantly more with corticotomies when compared with given dose of prostaglandin injection.

  10. Co-relation of body mass index, dental caries and periodontal status with fluorosis in different high fluoridated areas of Haryana state, India.

    Science.gov (United States)

    Vijayran, Manisha; Manuja, Naveen; Chaudhary, Seema; Sinha, Ashish; Chaitra, T R

    2014-01-01

    The aim of the present study is to compare the effect of corticotomy versus prostaglandin E1 injection in human subjects on rate of tooth movement, anchorage loss and their effect on crest bone height and root length. Clinical interventional study. Split mouth design was used. Study was done on 32 regular orthodontic patients. A volume of 100 mcg of prostaglandin E1 was injected on the right side once in 2 weeks and on the left side corticotomy was performed, and canine retraction was started on both sides simultaneously. The rate of space closure and anchorage loss was assessed with casts. The root length and crestal bone height changes were assed with IOPAs. The comparison of rate of tooth movement, anchorage loss, crestal bone height and root length changes between the sides were statistically analyzed using paired t-test. The average rate of space closure on right side was 0.36 mm/week with a standard deviation of 0.05 mm/week and on the left side average rate of space closure was 0.40 mm/week with a standard deviation of 0.04 mm/week. The difference between the rate of closure between the right side and left where found to be statistically significant (P=0.003). The anchorage loss, the crestal bone height changes and root length changes were not statistically significant. The rate of tooth movement was significantly more with corticotomies when compared with given dose of prostaglandin injection.

  11. Sources of product information used by consumers when purchasing kitchen cabinets.

    Science.gov (United States)

    Geoffrey H. Donovan; David L. Nicholls; Joseph. Roos

    2004-01-01

    Survey data from home shows in Seattle, Washington and Anchorage, Alaska were used to determine the sources of product information used by consumers when buying kitchen cabinets. Results show that in-store sales staff are the most common source of product information, and that consumers' favorite wood species, age, and gender can influence the source of product...

  12. 76 FR 42549 - Columbia Unlimited Hydroplane Races; Kennewick, WA

    Science.gov (United States)

    2011-07-19

    ... Unlimited Hydroplane Races; Kennewick, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Hydroplane Races. This regulation which restricts navigation and anchorage on the Columbia River for six days... Annual Kennewick, Washington, Columbia Unlimited Hydroplane Races (Water Follies). During the enforcement...

  13. Evidence-based knowledge creation on orthodontic mini-implants: ‘Why we know so little’

    NARCIS (Netherlands)

    Meursinge Reynders, R.A.

    2016-01-01

    Orthodontic mini-implants (OMIs) are used as anchorage devices to counteract the reciprocal forces of orthodontic tooth movement. The 5 systematic reviews and 2 critical appraisals included in this thesis created evidence-based knowledge on a variety of questions on these devices such as (1) their

  14. Mini-implants in orthodontics: A systematic review of the literature

    NARCIS (Netherlands)

    Reynders, Reint; Ronchi, Laura; Bipat, Shandra

    2009-01-01

    Introduction: In this article, we systematically reviewed the literature to quantify success and complications encountered with the use of mini-implants for orthodontic anchorage, and to analyze factors associated with success or failure. Methods: Computerized and manual searches were conducted up

  15. Investigation of bacteremia induced by removal of orthodontic mini-implants

    NARCIS (Netherlands)

    Livas, Christos; Delli, Konstantina; Karapsias, Stergios; Pandis, Nikolaos; Ren, Yijin

    The aim of this study was to investigate potential occurrence of bacteremia in orthodontic patients after removal of miniscrews.The study group comprised 30 healthy subjects (17 males, 13 females) with a mean age of 24.1 years treated with self-ligating fixed appliances and mini-implant anchorage.

  16. Shear strength of non-shear reinforced concrete elements

    DEFF Research Database (Denmark)

    Hoang, Cao linh

    1997-01-01

    model developed by Jin-Ping Zhang. The model takes into account the resistance against formation of cracks due to prestressing as well as the variation of the prestressing force in the transfer zone.Due to the fact that the anchorage of the reinforcement takes place by bond, a rotation failure, which...

  17. 33 CFR 110.190 - Tortugas Harbor, in vicinity of Garden Key, Dry Tortugas, Fla.

    Science.gov (United States)

    2010-07-01

    ... Garden Key, Dry Tortugas, Fla. 110.190 Section 110.190 Navigation and Navigable Waters COAST GUARD..., in vicinity of Garden Key, Dry Tortugas, Fla. (a) The anchorage grounds. All of Bird Key Harbor, southwest of Garden Key, bounded by the surrounding reefs and shoals and, on the northeast, by a line...

  18. Analysis and discussion on several problems when testing the thickness of reinforcement cover of concrete component

    Science.gov (United States)

    Zhanhua, Zhang; Guiling, Ji; Lijie; Zhaobo, Zhang; Na, Han; Jing, Zhao; Tan, Li; Zhaorui, Liu

    2018-03-01

    Reinforcement cover of concrete component plays a very important role to ensure the durability of various types of structures and the effective anchorage between steel reinforcement and concrete. This paper discusses and analyzes the problems occurred when testing the thickness of reinforcement cover of concrete component, so as to provide reference and help for related work.

  19. 77 FR 74508 - Notice of Availability of the Draft Resource Management Plan Amendment, Draft Environmental...

    Science.gov (United States)

    2012-12-14

    ... Environmental Impact Statement for the Ring of Fire Resource Management Plan--Haines Planning Area, Alaska... Cobbs, Anchorage District Planning and Environmental Coordinator, 907-267-1221, [email protected] , or in... the National Environmental Policy Act of 1969, as amended (NEPA), and the Federal Land Policy and...

  20. Feasibility Study Utilizing Meteor Burst Communications for Vessel Monitoring

    Science.gov (United States)

    1981-11-01

    4. EQUIPMENT The two meteor burst systems considered are the AMBCS with its Master Station located at Anchorage and an existing mobile government owned...requirement. However, since the mobile government owned system was specifi- cally designed for flight following applications, the transi- tion to ship

  1. Mutagenicity monitoring of urban air particles PM10 in the Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Černá, M.; Pastorková, A.; Šmíd, J.; Binková, Blanka

    2002-01-01

    Roč. 39, č. 33 (2002), s. 17 ISSN 0893-6692. [Environmental Mutagen Society Annual Meeting /33./. 27.04.2002-02.05.2002, Anchorage - USA] R&D Projects: GA MŽP SI/340/2/00 Keywords : urban air pollution * mutagenicity * PAHs Subject RIV: DN - Health Impact of the Environment Quality

  2. Endothelial induced EMT in breast epithelial cells with stem cell properties

    DEFF Research Database (Denmark)

    Sigurdsson, Valgardur; Hilmarsdottir, Bylgja; Sigmundsdottir, Hekla

    2011-01-01

    of keratins, a switch from E-Cadherin (E-Cad) to N-Cadherin (N-Cad) and enhanced migration. Acquisition of cancer stem cell associated characteristics like increased CD44(high)/CD24(low) ratio, resistance to apoptosis and anchorage independent growth was also seen in D492M cells. Endothelial induced EMT in D...

  3. 33 CFR 110.194a - Mobile Bay, Ala., and Mississippi Sound, Miss.

    Science.gov (United States)

    2010-07-01

    ... Sound, Miss. 110.194a Section 110.194a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Mississippi Sound, Miss. (a) The anchorage grounds. (1) The waters of lower Mobile Bay, near Cedar Point... south by latitude 30°20′00″, and on the west by longitude 88°06′00″. (2) The waters of Mississippi Sound...

  4. Strategies for Successful Retention of Alaska Native and American Indian Study Participants

    Science.gov (United States)

    Redwood, Diana; Leston, Jessica; Asay, Elvin; Ferucci, Elizabeth; Etzel, Ruth; Lanier, Anne P.

    2011-01-01

    This paper reports the strategies used to track and follow 3,828 Alaska Native and American Indian study participants in the city of Anchorage and more rural areas of Alaska and provides characteristics of respondents and non-respondents. Over 88% were successfully followed-up, with 49% of respondents completed in three or fewer attempts.…

  5. 14 CFR 217.10 - Instructions.

    Science.gov (United States)

    2010-01-01

    ... destination. BA—British Airways LHR—London, England ANC—Anchorage, USA NRT—Tokyo-Narita, Japan OSA—Osaka...-flight market. Use the 3-letter code from the City/Airport Codes section of the Official Airline Guide...) of this Appendix. (iv) Line A-4 Destination airport code. This is the arrival airport, where an...

  6. 75 FR 5167 - Office of Hazardous Materials Safety; Notice of Delays In Processing of Special Permits Applications

    Science.gov (United States)

    2010-02-01

    ...-2010 Anchorage, AK. 10945-M Structural Composites Industries, 4 03-31-2010 LLC Pomona, CA. 12629-M TEA... Trinity Industries, Inc. Dallas, TX 4 03-31-2010 14835-N The Reusable Industrial Packaging 4 03-31-2010... Company Baltimore, 4 03-31-2010 MD. 14883-N Structural Composites Industries 4 03-31-2010 (SCI) Pomona, CA...

  7. 76 FR 9868 - Office of Hazardous Materials Safety; Notice of Application for Special Permits

    Science.gov (United States)

    2011-02-22

    ... intermediate bulk containers for use as the outer packaging for certain Class waste paints and waste paint.... commerce of certain Anchorage, AK. flammable and combustible liquids in alternative packaging having a... Structural 49 CFR 173.302a and To authorize the Composites 173.304a. manufacture, marking, Industries, (SCI...

  8. The Tundra Is the Text: Using Alaska Native Contexts To Promote Cultural Relevancy in Teacher Professional Development.

    Science.gov (United States)

    Fickel, Letitia Hochstrasser; Jones, Ken

    In summer 2000, the University of Alaska Anchorage and cooperating professional development schools organized four summer institutes to enhance teachers' cultural and subject matter knowledge. This dual focus was prompted by the new Alaska Content Standards and by guidelines for preparing culturally responsive teachers, developed by Alaska Native…

  9. Mek activity is required for ErbB2 expression in breast cancer cells detached from the extracellular matrix.

    Science.gov (United States)

    Khan, Iman A; Yoo, Byong H; Rak, Janusz; Rosen, Kirill V

    2017-12-01

    Detachment of non-malignant epithelial cells from the extracellullar matrix (ECM) triggers their growth arrest and apoptosis. Conversely, carcinoma cells can grow without adhesion to the ECM. This capacity for anchorage-independent growth is thought to be critical for tumor progression. ErbB2/Her2 oncoprotein is overproduced by a significant fraction of breast cancers and promotes anchorage-independent tumor cell growth by poorly understood mechanisms. In an effort to understand them we found that in order to produce ErbB2, detached breast cancer cells require the activity of an ErbB2 effector protein kinase Mek and that Mek-driven ErbB2 expression is neccesary for anchorage-independent growth of such cells. We observed that Mek inhibition does not alter ErbB2 mRNA levels in detached cancer cells and that ErbB2 protein loss induced by this inhibition can be blocked by a lysosomal inhibitor. We also noticed that an increase of the density of cancer cells detached from the ECM downregulates a Mek effector protein kinase Erk and causes ErbB2 loss. Those cells that survive after ErbB2 loss display resistance to trastuzumab, an anti-ErbB2 antibody used for ErbB2-positive breast cancer treatment. Thus, Mek-induced ErbB2 stabilization in detached breast cancer cells is critical for their ability to grow anchorage-independently and their trastuzumab sensitivity.

  10. On the Theory of Ground Anchors

    Science.gov (United States)

    1975-01-01

    Anchorages in Frozen Materials. Technical review of the report was performed by Edwin Chamberiain of USA CRREL. The contents of this report are not to...Laboratories. Technical Report 67-54-OP. Sutherland , lI.B. (1965) Model studies for shaft raising though cohesionless soils. Pro- ceedings 6th International

  11. Miniscrew implant applications in contemporary orthodontics

    Directory of Open Access Journals (Sweden)

    Hong-Po Chang

    2014-03-01

    Full Text Available The need for orthodontic treatment modalities that provide maximal anchorage control but with minimal patient compliance requirements has led to the development of implant-assisted orthodontics and dentofacial orthopedics. Skeletal anchorage with miniscrew implants has no patient compliance requirements and has been widely incorporated in orthodontic practice. Miniscrew implants are now routinely used as anchorage devices in orthodontic treatment. This review summarizes recent data regarding the interpretation of bone data (i.e., bone quantity and quality obtained by preoperative diagnostic computed tomography (CT or by cone-beam computed tomography (CBCT prior to miniscrew implant placement. Such data are essential when selecting appropriate sites for miniscrew implant placement. Bone characteristics that are indications and contraindications for treatment with miniscrew implants are discussed. Additionally, bicortical orthodontic skeletal anchorage, risks associated with miniscrew implant failure, and miniscrew implants for nonsurgical correction of occlusal cant or vertical excess are reviewed. Finally, implant stability is compared between titanium alloy and stainless steel miniscrew implants.

  12. 75 FR 38093 - ConocoPhillips Alaska Natural Gas Corporation and Marathon Oil Company; Application for Blanket...

    Science.gov (United States)

    2010-07-01

    ... located near Kenai, Alaska, to Japan and/ or one or more other countries globally with which trading is... place of business in Anchorage, Alaska, is a wholly-owned subsidiary of ConocoPhillips Company, a publicly-traded Delaware corporation. Marathon is an Ohio corporation with its principal place of business...

  13. 77 FR 39395 - Special Local Regulations; Ocean State Tall Ships Festival 2012, Narragansett Bay, RI

    Science.gov (United States)

    2012-07-03

    ... docket number in the ``SEARCH'' box and click ``SEARCH.'' Click on Open Docket Folder on the line...) Area Potter Cove: This Area is of the same coordinates as that portion of charted Anchorage A, as... behind numerous other spectator craft viewing the moored Tall Ships. (ii) Area Potter Cove: This area is...

  14. Case Studies Nested in Fuzzy-Set QCA on Sufficiency: Formalizing Case Selection and Causal Inference

    Science.gov (United States)

    Schneider, Carsten Q.; Rohlfing, Ingo

    2016-01-01

    Qualitative Comparative Analysis (QCA) is a method for cross-case analyses that works best when complemented with follow-up case studies focusing on the causal quality of the solution and its constitutive terms, the underlying causal mechanisms, and potentially omitted conditions. The anchorage of QCA in set theory demands criteria for follow-up…

  15. Corticotomy-assisted retraction: An outcome assessment

    Directory of Open Access Journals (Sweden)

    S Vijayashri Sakthi

    2014-01-01

    Conclusion: The rate of retraction with study group was twice as faster when compared to the control group, accelerating during the first 2 months of retraction. There was better anchorage control with the undecorticated molar segment during the retraction period but was found to increase as time advanced.

  16. Variability in the root system of East African banana genotypes ...

    African Journals Online (AJOL)

    The banana (Musa spp.) root system is important for plant anchorage and the uptake of nutrients and water and thus, strongly influences plant growth and subsequent yields. Previous research studies on the Musa spp. root system have predominantly focused on high value export dessert bananas (AAA group) and ...

  17. Download this PDF file

    African Journals Online (AJOL)

    armour was fitted all around the wheel house and armoured screens with small apertures could be flapped down to cover the windows. For manoeuvrability within harbours or in crowded anchorages, a twin screw arrangement was essen- tial. The craft were powered by two eight cylinder. Gardner in-line diesels giving them ...

  18. Mandibular molar uprighting using orthodontic miniscrew implants: a systematic review

    Directory of Open Access Journals (Sweden)

    Panagiota Magkavali-Trikka

    2018-01-01

    Full Text Available Abstract The purpose of this systematic review was to identify studies and present the use of miniscrew implants (MIs as an alternative treatment to mandibular molar uprighting. An electronic search and handsearching were conducted by two independent reviewers to identify relevant articles, published up to January 27, 2017. In order to methodologically assess the eligible studies, a pilot checklist consisting of 22 items was also implemented. After exclusion of all the irrelevant papers, only 17 studies were included, presenting 27 cases of mandibular molar uprighting in all planes using both direct and indirect force traction by MIs. Regarding the quality evaluation, the mean score of the included studies was 13.2, indicating a rather poor methodology implemented in the majority of the included cases. Due to many advantages, MIs provide a unique treatment alternative and constitute a reliable solution for treating tipped or impacted molars. Regarding the force application, a direct method is simpler, as it requires one MI and a single bracket or button, minimizing the patient’s discomfort and also reducing chair time compared to more complex indirect anchorage. It also eliminates the possibility of unwanted movement of the anchorage unit, which can occur even with indirect anchorage as a result of technical errors. However, direct anchorage has limitations in cases of lingually tipped or rotated molars because a single force may be insufficient to upright the tooth.

  19. 29 CFR 1926.758 - Systems-engineered metal buildings.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Systems-engineered metal buildings. 1926.758 Section 1926... Systems-engineered metal buildings. (a) All of the requirements of this subpart apply to the erection of systems-engineered metal buildings except §§ 1926.755 (column anchorage) and 1926.757 (open web steel...

  20. 77 FR 14269 - IFR Altitudes; Miscellaneous Amendments

    Science.gov (United States)

    2012-03-09

    ... Read in Part NOME, AK VOR/DME HLBLY, AK FIX 18000 45000 GNSS REQUIRED HLBLY, AK FIX ANCHORAGE, AK VOR/DME 18000 45000 GNSS REQUIRED Sec. 95.4051 RNAV Route Q51 Is Amended to Read in Part KING SALMON, AK VORTAC SLIIM, AK FIX 18000 45000 GNSS REQUIRED SLIIM, AK FIX HLBLY, AK FIX 18000 45000 GNSS REQUIRED...