WorldWideScience

Sample records for anchor-based mic distribution

  1. Comparison of Distribution- and Anchor-Based Approaches to Infer Changes in Health-Related Quality of Life of Prostate Cancer Survivors

    Science.gov (United States)

    Jayadevappa, Ravishankar; Malkowicz, Stanley Bruce; Wittink, Marsha; Wein, Alan J; Chhatre, Sumedha

    2012-01-01

    Objective To determine the minimal important difference (MID) in generic and prostate-specific health-related quality of life (HRQoL) using distribution- and anchor-based methods. Study Design and Setting Prospective cohort study of 602 newly diagnosed prostate cancer patients recruited from an urban academic hospital and a Veterans Administration hospital. Participants completed generic (SF-36) and prostate-specific HRQoL surveys at baseline and at 3, 6, 12, and 24 months posttreatment. Anchor-based and distribution-based methods were used to develop MID estimates. We compared the proportion of participants returning to baseline based on MID estimates from the two methods. Results MID estimates derived from combining distribution- and anchor-based methods for the SF-36 subscales are physical function = 7, role physical = 14, role emotional = 12, vitality = 9, mental health = 6, social function = 9, bodily pain = 9, and general health = 8; and for the prostate-specific scales are urinary function = 8, bowel function = 7, sexual function = 8, urinary bother = 9, bowel bother = 8, and sexual bother = 11. Proportions of participants returning to baseline values corresponding to MID estimates from the two methods were comparable. Conclusions This is the first study to assess the MID for generic and prostate-specific HRQoL using anchor-based and distribution-based methods. Although variation exists in the MID estimates derived from these two methods, the recovery patterns corresponding to these estimates were comparable. PMID:22417225

  2. Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin.

    Science.gov (United States)

    Yu, Xia; Wang, Guirong; Chen, Suting; Wei, Guomei; Shang, Yuanyuan; Dong, Lingling; Schön, Thomas; Moradigaravand, Danesh; Parkhill, Julian; Peacock, Sharon J; Köser, Claudio U; Huang, Hairong

    2016-09-01

    Antofloxacin (AFX) is a novel fluoroquinolone that has been approved in China for the treatment of infections caused by a variety of bacterial species. We investigated whether it could be repurposed for the treatment of tuberculosis by studying its in vitro activity. We determined the wild-type and non-wild-type MIC ranges for AFX as well as ofloxacin (OFX), levofloxacin (LFX), and moxifloxacin (MFX), using the microplate alamarBlue assay, of 126 clinical Mycobacterium tuberculosis strains from Beijing, China, of which 48 were OFX resistant on the basis of drug susceptibility testing on Löwenstein-Jensen medium. The MIC distributions were correlated with mutations in the quinolone resistance-determining regions of gyrA (Rv0006) and gyrB (Rv0005). Pharmacokinetic/pharmacodynamic (PK/PD) data for AFX were retrieved from the literature. AFX showed lower MIC levels than OFX but higher MIC levels than LFX and MFX on the basis of the tentative epidemiological cutoff values (ECOFFs) determined in this study. All strains with non-wild-type MICs for AFX harbored known resistance mutations that also resulted in non-wild-type MICs for LFX and MFX. Moreover, our data suggested that the current critical concentration of OFX for Löwenstein-Jensen medium that was recently revised by the World Health Organization might be too high, resulting in the misclassification of phenotypically non-wild-type strains with known resistance mutations as wild type. On the basis of our exploratory PK/PD calculations, the current dose of AFX is unlikely to be optimal for the treatment of tuberculosis, but higher doses could be effective. PMID:27324769

  3. Speedy Mic's Photograph

    Science.gov (United States)

    2007-12-01

    Using observations from ESO's VLT, astronomers were able for the first time to reconstruct the site of a flare on a solar-like star located 150 light years away. The study of this young star, nicknamed 'Speedy Mic' because of its fast rotation, will help scientists better understand the youth of our Sun. ESO PR Photo 53/07 ESO PR Photo 53/07 Mapping Spots on Speedy Mic The astronomers [1] observed the star BO Microscopii [2] during two consecutive nights in October 2006, simultaneously with the UVES spectrograph on ESO's Very Large Telescope and ESA's XMM-Newton X-ray satellite. Using a technique called 'Doppler imaging' [3], the astronomers reconstructed images of the surface of the star, detecting the presence of several spots. A few are near the visible pole, while most spots are asymmetrically distributed at mid-latitudes. "The image we could secure of Speedy Mic is, given its distance, a real achievement, that allows us to localise for the first time ever the source of a flare and its surrounding," says Uwe Wolter, lead author of the paper relating the discovery. The X-ray observations indeed identified several flares, which are sudden and vast releases of energy. For one of them, the astronomers could pinpoint its origin on the surface of the star. The flare, lasting about 4 hours, was a hundred times more energetic than a large solar flare and considerably larger than solar coronal loops. The surprising finding, the team says, was the location of the flare. Contrary to our Sun, the site of the observed flare does not correspond to the detected spots [4]. "Interestingly, the flare occurs on a rather inconspicuous portion of the star's surface, away from the main concentration of activity in terms of dark spots," explains Wolter. Speedy Mic is a very young star: with an age of only about 30 million years, it is roughly 150 times younger than the Sun. "It is very likely that our young Sun was a fast rotator as well," says Wolter. "Studying Speedy Mic is thus

  4. Determination of MIC distribution of arbekacin, cefminox, fosfomycin, biapenem and other antibiotics against gram-negative clinical isolates in South India: a prospective study.

    Directory of Open Access Journals (Sweden)

    Sangeetha Rajenderan

    Full Text Available To determine the in vitro activity of antibiotics, including arbekacin, cefminox, fosfomycin and biapenem which are all still unavailable in India, against Gram-negative clinical isolates.We prospectively collected and tested all consecutive isolates of Escherichia coli, Klebsiella spp., Pseudomonas aeruginosa and Acinetobacter spp. from blood, urine and sputum samples between March and November 2012. The minimum inhibition concentration (MIC of 16 antibiotics was determined by the broth micro-dilution method.Overall 925 isolates were included; 211 E. coli, 207 Klebsiella spp., 153 P. aeruginosa, and 354 Acinetobacter spp. The MIC50 and MIC90 were high for cefminox, biapenem and arbekacin for all pathogens but interpretative criteria were not available. The MIC50 was categorized as susceptible for a couple of antibiotics, including piperacillin/tazobactam, carbapenems and amikacin, for E. coli, Klebsiella spp. and P. aeruginosa. However, for Acinetobacter spp., the MIC50 was categorized as susceptible only for colistin. On the other hand, fosfomycin was the only antibiotic that inhibited 90% of E. coli and Klebsiella spp. isolates, while 90% of P. aeruginosa isolates were inhibited only by colistin. Finally, 90% of Acinetobacter spp. isolates were not inhibited by any antibiotic tested.Fosfomycin and colistin might be promising antibiotics for the treatment of infections due to E. coli or Klebsiella spp. and P. aeruginosa, respectively, in India; however, clinical trials should first corroborate the in vitro findings. The activity of tigecycline should be evaluated, as this is commonly used as last-resort option for the treatment of multidrug-resistant Acinetobacter infections.

  5. Determination of MIC distribution and epidemiological cutoff values for bedaquiline and delamanid in Mycobacterium tuberculosis using the MGIT 960 system equipped with TB eXiST.

    Science.gov (United States)

    Keller, Peter M; Hömke, Rico; Ritter, Claudia; Valsesia, Giorgia; Bloemberg, Guido V; Böttger, Erik C

    2015-07-01

    Bedaquiline (Sirturo) and delamanid (Deltyba) have recently been approved by the regulatory authorities for treatment of multidrug-resistant tuberculosis (MDR-TB). Antimicrobial susceptibility testing is not established for either substance. On the basis of the use of the MGIT 960 system equipped with EpiCenter/TB eXiST, we determined a mean bedaquiline MIC for wild-type strains of 0.65 mg/liter (median, 0.4 mg/liter) and an epidemiological cutoff (ECOFF) of 1.6 mg/liter; for delamanid, a mean wild-type drug MIC of 0.013 mg/liter (median, 0.01 mg/liter) and an ECOFF of 0.04 mg/liter were determined. PMID:25941226

  6. Determination of MIC Distribution and Epidemiological Cutoff Values for Bedaquiline and Delamanid in Mycobacterium tuberculosis Using the MGIT 960 System Equipped with TB eXiST

    OpenAIRE

    Peter M Keller; Hömke, Rico; Ritter, Claudia; Valsesia, Giorgia; Bloemberg, Guido V.; Böttger, Erik C.

    2015-01-01

    Bedaquiline (Sirturo) and delamanid (Deltyba) have recently been approved by the regulatory authorities for treatment of multidrug-resistant tuberculosis (MDR-TB). Antimicrobial susceptibility testing is not established for either substance. On the basis of the use of the MGIT 960 system equipped with EpiCenter/TB eXiST, we determined a mean bedaquiline MIC for wild-type strains of 0.65 mg/liter (median, 0.4 mg/liter) and an epidemiological cutoff (ECOFF) of 1.6 mg/liter; for delamanid, a mea...

  7. Anchor-Based Methods for Judgmentally Estimating Item Difficulty Parameters. LSAC Research Report Series.

    Science.gov (United States)

    Hambleton, Ronald K.; Sireci, Stephen G.; Swaminathan, H.; Xing, Dehui; Rizavi, Saba

    The purposes of this research study were to develop and field test anchor-based judgmental methods for enabling test specialists to estimate item difficulty statistics. The study consisted of three related field tests. In each, researchers worked with six Law School Admission Test (LSAT) test specialists and one or more of the LSAT subtests. The…

  8. The frequent occurrence of MIC

    Energy Technology Data Exchange (ETDEWEB)

    Graff, Matthias [Gesellschaft fuer Technische Mikrobiologie und Hygieneueberwachung - Dr. Graff und Partner, Stadtweg 9, D-38176 Wendeburg (Germany); Neubert, Volkmar [Institut fuer Materialpruefung und Werkstofftechnik Dr. Doelling und Dr. Neubert GmbH, Freiberger Strasse 1, D-38678 Clausthal-Zellerfeld (Germany)

    2004-07-01

    Microbial induced corrosion (MIC) is not as rare as many materials scientist and corrosion practitioners do believe. It is not an exotic and scarce event, but can be found frequently in many fields of corrosion research, provided that it is looked for. The reason for the relatively few descriptions of MIC cases seems to be the fact, that the microbiological approach is not widely known and applied in the world of materials science. MIC is not so much a corrosion mechanism on its own, but it enhances the corrosion rates of the 'normal' mechanisms to such an extent, that in some cases 'incredible' fast corrosion progress can be observed. The reason is the microorganisms' function as bio-catalysts: Chemical reactions, which are very slow under normal chemical conditions can be highly accelerated by living organisms. Besides that, several microorganisms do produce very corrosive substances which in natural environments do not occur without the activity of microorganisms, e. g. sulfuric or nitric acid. We want to point out, that it can be very worthy to take microbial induced corrosion into account. MIC is not the general answer for all unsolved corrosion problems, but to think about it helps in many corrosion cases as the authors had to experience. The initial indication for the presence of MIC are markedly increased corrosion rates. In the following, some of our 'lessons' are presented as short case studies: Two of them deal with steel corrosion characterized by increased corrosion rates. The third example presents corrosion damage of aluminium structures, where from a technical point of view corrosion was not expected, least of all microbial induced corrosion. (authors)

  9. An Anchor-Based Pedestrian Navigation Approach Using Only Inertial Sensors.

    Science.gov (United States)

    Gu, Yang; Song, Qian; Li, Yanghuan; Ma, Ming; Zhou, Zhimin

    2016-01-01

    In inertial-based pedestrian navigation, anchors can effectively compensate the positioning errors originating from deviations of Inertial Measurement Units (IMUs), by putting constraints on pedestrians' motions. However, these anchors often need to be deployed beforehand, which can greatly increase system complexity, rendering it unsuitable for emergency response missions. In this paper, we propose an anchor-based pedestrian navigation approach without any additional sensors. The anchors are defined as the intersection points of perpendicular corridors and are considered characteristics of building structures. In contrast to these real anchors, virtual anchors are extracted from the pedestrian's trajectory and are considered as observations of real anchors, which can accordingly be regarded as inferred building structure characteristics. Then a Rao-Blackwellized particle filter (RBPF) is used to solve the joint estimation of positions (trajectory) and maps (anchors) problem. Compared with other building structure-based methods, our method has two advantages. The assumption on building structure is minimum and valid in most cases. Even if the assumption does not stand, the method will not lead to positioning failure. Several real-scenario experiments are conducted to validate the effectiveness and robustness of the proposed method. PMID:26959031

  10. NICHD Microscopy and Imaging Core (MIC)

    Data.gov (United States)

    Federal Laboratory Consortium — The NICHD Microscopy and Imaging Core (MIC) is designed as a multi-user research facility providing training and instrumentation for high resolution microscopy and...

  11. Application Research on Nondestructive Testing Technology for Quality of Anchor Based on Elastic Wave Reflection Method

    Science.gov (United States)

    Xiao, G.; Zhou, L.

    2014-12-01

    Anchor technology has been widely used to reinforce slopes, underground caverns, deep excavations and the foundation of dams. It has attracted more and more attention of research worldwide on how to find a comfortable method to test the quality of anchoring systems. According to the characteristics of anchor systems, we set up the kinetic equations and mathematical models, then solved the models using ANSYS / LS-DYNA program. We found that the simulated mathematical models perfectly match the experimental data. By changing one of the parameters or the input conditions in the model, we were able to understand the characteristic response of excitation energy, excitation length, structural defects, rock quality, and different data acquisition methods. For short anchor systems (grouting density. The obtained values were consistent with the actual experimental data. We also demonstrated that the kinetic energy of the collected waves from the bottom of the anchor had very close relationship with the grouting density and the position of the structural defects. For long anchors (> 60 m), mostly cable anchors, since little research could be followed, we started our research from designing the instrument, writing the program for data acquisition and analysis. We designed and developed novel sensors and preamplifiers. We used vertical stack technology to effectively enhance the weak signals from the deeper interfaces. In data processing, in addition to the traditional filter method, we also explored the current technology of signal processing such as true amplitude recovery and deconvolution, which enabled us to obtain improved signal to noise ratio and sensing precision. Through the above mentioned systematical studies, we developed a reliable nondestructive test method for both short and long anchors based on elastic wave reflection. This research is funded by National Natural Science Foundation of China (Grant No. 41202223)

  12. MIC16 gene represents a potential novel genetic marker for population genetic studies of Toxoplasma gondii

    OpenAIRE

    Liu, Wen-Ge; Xu, Xiao-Pei; Chen, Jia; Xu, Qian-Ming; Luo, Si-Long; Zhu, Xing-Quan

    2016-01-01

    Background The zoonotic agent Toxoplasma gondii is distributed world-wide, and can infect a broad range of hosts including humans. Microneme protein 16 of T. gondii (TgMIC16) is responsible for binding to aldolase, and is associated with rhomboid cleavage and presence of trafficking signals during invasion. However, little is known of the TgMIC16 sequence diversity among T. gondii isolates from different hosts and geographical locations. Results In this study, we examined sequence variation i...

  13. The triple system AT Mic AB + AU Mic in the beta Pictoris Association

    CERN Document Server

    Messina, Sergio; Pagano, Isabella

    2016-01-01

    Equal-mass stars in young open clusters and loose associations exhibit a wide spread of rotation periods, which likely originates from differences in the initial rotation periods and in the primordial disc lifetimes. We want to explore if the gravitational effects by nearby companions may play an additional role in producing the observed rotation period spread. We measure the photometric rotation periods of components of multiple stellar systems and look for correlations of the period differences among the components to their reciprocal distances. In this paper, we analysed the triple system AU Mic + AT Mic A&B in the 25-Myr beta Pictoris Association. We have retrieved from the literature the rotation period of AU Mic (P = 4.85d) and measured from photometric archival data the rotation periods of both components of AT Mic (P = 1.19d and P = 0.78d) for the first time. Moreover, we detected a high rate of flare events from AT Mic. Whereas the distant component AU Mic has evolved rotationally as a single sta...

  14. Mechanical mechanism analysis of tension type anchor based on shear displacement method

    Institute of Scientific and Technical Information of China (English)

    XIAO Shu-jun; CHEN Chang-fu

    2008-01-01

    Based on the fact that the shear stress along anchorage segment is neither linearly nor uniformly distributed, the load transfer mechanism of the tension type anchor was studied and the mechanical characteristic of anchorage segment was analyzed. Shear stress-strain relationship of soil surrounding anchorage body was simplified into three-folding-lines model consisting of elastic phase, elasto-plastic phase and residual phase considering its softening eharaeteristic. Meanwhile, shear displacement method that has been extensively used in the analysis of pile foundation was introduced. Based on elasto-plastic theory, the distributions of displacement, shear stress and axial force along the anchorage segment of tension type anchor were obtained, and the formula for calculating the elastic limit load was also developed accordingly. Finally, an example was given to discuss the variation of stress and displacement in the anchorage segment with the loads exerted on the anchor, and a program was worked out to calculate the anchor maximum bearing capacity. The influence of some parameters on the anchor bearing capacity was discussed, and effective anchorage length was obtained simultaneously. The results show that the shear stress first increases and then decreases and finally trends to theresidual strength with increase of distance from bottom of the anchorage body, the displacement increases all the time with theincrease of distance from bottom of the anchorage body, and the increase of velocity gradually becomes greater.

  15. Initial Results from the CRRES/MICS Empirical Model of Ion Plasma in the Inner Magnetosphere

    Science.gov (United States)

    Claudepierre, Seth; Roeder, James; Chen, Margaret; Lemon, Colby; Guild, Timothy

    2013-04-01

    We present initial results from a recently developed empirical model of low energy ion plasma (~1-300 keV/e) in the inner magnetosphere. This model is constructed from data taken by the Magnetospheric Ion Composition Spectrometer (MICS) on-board the Combined Release and Radiation Effects Satellite (CRRES). The model has been constructed in a similar fashion to the Roeder et al., [2005] CAMMICE/MICS model, which used NASA Polar satellite data. The orbital differences between CRRES (GTO) and Polar (highly-inclined polar orbit) result in each spacecraft sampling different portions of the ion pitch-angle distributions. Such models can be used to estimate the average flux for major ion species (e.g. H+, He+, He++, O+) along any orbit in the inner magnetosphere. To construct this new model, CRRES/MICS ion fluxes were computed and sorted into bins of magnetic coordinates L, MLT, MLAT, equatorial pitch-angle and activity indices. Preliminary comparisons are made between the CAMMICE/MICS and CRRES/MICS models, highlighting the strengths and limitations of both. We also consider the average O+ ion flux deduced from the model in various spatial and activity ranges and qualitatively compare with what is to be expected from O+ ion transport and loss processes.

  16. Mic Flocks in the Cloud: Harnessing Mobile Ubiquitous Sensor Networks

    Science.gov (United States)

    Garces, M. A.; Christe, A.

    2015-12-01

    Smartphones provide a commercial, off-the-shelf solution to capture, store, analyze, and distribute infrasound using on-board or external microphones (mics) as well as on-board barometers. Free iOS infrasound apps can be readily downloaded from the Apple App Store, and Android versions are in progress. Infrasound propagates for great distances, has low sample rates, and provides a tractable pilot study scenario for open distributed sensor networks at regional and global scales using one of the most ubiquitous sensors on Earth - microphones. Data collection is no longer limited to selected vendors at exclusive prices: anybody on Earth can record and stream infrasound, and the diversity of recording systems and environments is rapidly expanding. Global deployment may be fast and easy (www.redvox.io), but comes with the cost of increasing data volume, velocity, variety, and complexity. Flocking - the collective motion of mobile agents - is a natural human response to threats or events of interest. Anticipating, modeling and harnessing flocking sensor topologies will be necessary for adaptive array and network processing. The increasing data quantity and complexity will exceed the processing capacity of human analysts and most research servers. We anticipate practical real-time applications will require the on-demand adaptive scalability and resources of the Cloud. Cloud architectures for such heterogeneous sensor networks will consider eventual integration into the Global Earth Observation System of Systems (GEOSS).

  17. Development of biological coal gasification (MicGAS Process)

    Energy Technology Data Exchange (ETDEWEB)

    1992-07-28

    This report describes progress on three fronts of the project. First in studies to elucidate optimal growing conditions for the consortia of coal degraders employed indicates that best growth occurs with 0. 2% w/v Shefton T. Secondly in comparing the biodegradative properties of the coal degraders, isolates identified as Mic-1 and Mic-4 were the best performers. And lastly bioreactors studies in batch mode are related.

  18. Use of checkpoint-restart for complex HEP software on traditional architectures and Intel MIC

    International Nuclear Information System (INIS)

    Process checkpoint-restart is a technology with great potential for use in HEP workflows. Use cases include debugging, reducing the startup time of applications both in offline batch jobs and the High Level Trigger, permitting job preemption in environments where spare CPU cycles are being used opportunistically and efficient scheduling of a mix of multicore and single-threaded jobs. We report on tests of checkpoint-restart technology using CMS software, Geant4-MT (multi-threaded Geant4), and the DMTCP (Distributed Multithreaded Checkpointing) package. We analyze both single- and multi-threaded applications and test on both standard Intel x86 architectures and on Intel MIC. The tests with multi-threaded applications on Intel MIC are used to consider scalability and performance. These are considered an indicator of what the future may hold for many-core computing

  19. Operational measures for the mitigation of MIC [microbiologically influenced corrosion

    International Nuclear Information System (INIS)

    Although entitled Operational Measure, this section of the workshop encompasses aspects of mitigating MIC by controlling the hydraulic characteristics of a system. In order for operational considerations outside of the chemical treatment program to be effective, the system must be designed, constructed or modified, and maintained with MIC in mind. Since other papers in these proceedings discuss in detail the proper selection of materials, chemical treatments and detection of monitoring techniques, this paper is limited to quidelines for mitigating MIC and its effects by the mechanical design, maintenance and operation of the system. The key concept behind this philosophy is the synergistic relationships among microbes and among microbes and larger biofouling organisms. If the slime formers or other marine organisms can be prevented from attaching to the components, conducive environments for attack by other species is avoided

  20. The BinaMIcS project: binarity and magnetism

    Science.gov (United States)

    Neiner, C.; Alecian, E.

    2013-02-01

    We present the BinaMIcS project, its goals and the first BinaMIcS spectropolarimetric observations obtained with Narval at TBL and ESPaDOnS at CFHT: dedicated time-series for targeted hot and cool close double-line spectroscopic (SB2) binaries and a survey of hot close SB2 binaries. The very first results are also presented. In particular, our first survey observations seem to show a lack of magnetic fields in hot close binaries compared to single stars.

  1. The BinaMIcS project: binarity and magnetism

    OpenAIRE

    Neiner, C.; Alecian, E.; collaboration, the BinaMIcS

    2013-01-01

    We present the BinaMIcS project, its goals and the first BinaMIcS spectropolarimetric observations obtained with Narval at TBL and ESPaDOnS at CFHT: dedicated time-series for targeted hot and cool close double-line spectroscopic (SB2) binaries and a survey of hot close SB2 binaries. The very first results are also presented. In particular, our first survey observations seem to show a lack of magnetic fields in hot close binaries compared to single stars.

  2. Gradient Plate for Hicomb Minimum Inhibitory Concentration (MIC Test

    Directory of Open Access Journals (Sweden)

    Fatemi Motlagh M

    2011-01-01

    Full Text Available Bakground and objectives: "The comb antibiotic sensitivity test" is a quick,reliable and cost effective method to determine the susceptibility of bacteriato different antibiotics. The purpose of this study is to design a plate that iseasy and quick to use, and enable to be interpreted easily without the need formeasurement of the margins with a ruler.Material and Methods: First, Clinical and Laboratory Standards Institutedata about the maximum growth inhibitory haloes formed with antibioticsand various micro-organisms were statistically examined and determinedthat the most (99.7% zone of inhibition growth is formed in the range of 42mm. Accordingly, the obtained number (42 mm and conventional plate size(100 mm used for testing sensitivity were punched into Solid workssoftware which was used to determine the best place of strip and shoulderplates. After that the efficacy this media were examined by determination ofMIC Staphylococcus aureus and Klebsiella pneumonia, non-graded andgraded plate shoulders were searched and compared.Results: Has been placed two combs MIC in a plate in this method anddidn’t create growth inhibitory haloes interferences. Obtained MIC forNitrofurantoin( 10 μg/ml , Amikacin(0.5 μg/ml, Gentamicin(1 μg/ml , andAmoxicillin (0.5 μg/ml against S.aureus , MIC Nalidicsic Acid, Amikcin,Gentamicin and Nitrofurantoin against K.pneumonia was 0.1, 0.5, 0.5 and 10μg/ml ,respectively.Conclusion:The comparison between this new innovative method andstandard methods (Clinical Laboratory Standards Institute - CLSI shows thatthere a marked reduction in the interference of antibiotic therapy and willalso reduce time of interpretation.Key words: Plate, Antibiogram Comb, MIC, Antibiotics, Drug resistance

  3. Aprender a narrar con el cómic

    OpenAIRE

    Prado Aragonés, Josefina

    1995-01-01

    Proponemos la utilización del cómic en el aula como recurso didáctico para iniciar a nuestros alumnos en la lectura crítica de la imagen y en el conocimiento del género narrativo. Uno de los medios de comunicación más atractivo para niños y jóvenes y más característico de la cultura contemporánea, denominada «cultura de la imagen», es el cómic. Con este nombre genérico denominamos una serie de publicaciones: tebeos, tiras, historietas gráficas; cuyo tema, inicialmente cómico, pronto se divers...

  4. El cómic feminista: un poco de historia

    OpenAIRE

    Díez Balda, María Antonia

    2011-01-01

    [ES] El cómic es un medio de comunicación popular en el que la narración se resuelve con viñetas dibujadas acompañadas de globos y textos breves. Se editan en serie en tiras o páginas de los periódicos o en cuadernillos independientes y se utilizan para la narración de una anécdota, un chiste o un relato. Los cómics son de fácil lectura, asequibles para todos los públicos, por eso son importantes en la educación infantil, en la transmisión de estereotipos de género y en la propaganda polít...

  5. Threshold SRB populations for MIC of stainless alloys

    International Nuclear Information System (INIS)

    The three CANDU reactor sites on the Great Lakes exhibit differences in susceptibility to microbially influenced corrosion (MIC) of heat exchanger tubes, despite similar colonization of sulfate-reducing bacteria (SRB). Therefore, it was suspected that bacterial activity, rather than numbers, is responsible for pit initiation. Accelerated corrosion tests are being used to examine the relationship between SRB colonization and pitting activity on stainless alloy heat exchanger tubes. Experimental conditions model those of the natural systems. At present, there appears to be little correlation between bacterial numbers and pit initiation. However, there does appear to be a correlation between bacterial activity (causing a decrease in corrosion potential, as a function of sulfide production), and pit initiation. Data are being collected to develop a model to predict MIC for the CHECWORKS service water module. (author)

  6. MICs and MBCs of chemotherapeutic agents against Renibacterium salmoninarum.

    Science.gov (United States)

    Bandín, I; Santos, Y; Toranzo, A E; Barja, J L

    1991-05-01

    The efficacies of 21 chemotherapeutic agents for controlling bacterial kidney disease were evaluated. The bactericidal and/or bacteriostatic effects of these drugs were tested against 11 Renibacterium salmoninarum strains with different origins. The most effective compounds displaying both bacteriostatic and bactericidal activity for all the isolates were tetracycline and erythromycin, with MICs ranging from less than 0.62 to 10.95 micrograms/ml for tetracycline and from less than 0.62 to 5.47 micrograms/ml for erythromycin. Whereas tetracycline showed identical MICs and MBCs, erythromycin showed bactericidal effects at concentrations of 5.47 to 21.87 micrograms/ml. Similarly, cefazolin and tiamulin proved to be very effective bactericidal compounds against the majority of R. salmoninarum isolates, with MBCs for 90% of the strains tested of 21.87 and 10.95 micrograms/ml, respectively. Neither nitrofuranes, quinolones, nor sulfonamides showed inhibitory effects on the growth of the strains. PMID:1854157

  7. First experiences with the Intel MIC architecture at LRZ

    OpenAIRE

    Weinberg, Volker; Allalen, Momme

    2013-01-01

    With the rapidly growing demand for computing power new accelerator based architectures have entered the world of high performance computing since around 5 years. In particular GPGPUs have recently become very popular, however programming GPGPUs using programming languages like CUDA or OpenCL is cumbersome and error-prone. Trying to overcome these difficulties, Intel developed their own Many Integrated Core (MIC) architecture which can be programmed using standard parallel programming techniq...

  8. A Brief Review of General Patterns of MIC of Carbon Steel and Biodegradation of Concrete

    OpenAIRE

    Javaherdashti, Reza

    2010-01-01

    MIC (Microbiologically influenced corrosion) is an electrochemical type of corrosion enhanced by some types of micro-/ macro-organisms. However, in this paper, MIC will be used to address the corrosion enhanced by micro-organisms. In order for MIC to occur, two minimum requirements are (i) vulnerability of the material and (ii) existence of environmental factors that are favoring MIC. This type of corrosion is known to affect both metals and non-metals. On the other hand, the factors that ren...

  9. SUBKLONING DAN ISOLASI GEN PENYANDI MIKRONEMA 3 (MIC-3) Toxoplasma gondii ISOLAT LOKAL

    OpenAIRE

    Diana Indrasanti; Aris Haryanto; Wayan T. Artama

    2011-01-01

    Microneme protein (MIC) is one of proteins that belongs to excretory-secretory antigens (ESAs) of Toxoplasma gondii. Microneme 3 protein (MIC-3) is the protein that plays an important role in the invasion proccess during cell infection as a mediator attachment parasite to the host cell. The aim of this research is to clone mic3 (gene encoding for MIC-3) of T. gondii from local isolate using recombinant DNA technology by cloning mic3 in an expression vector. Deoxyribonucleic acid (DNA) from T....

  10. ENVIRONMENTAL BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    International Nuclear Information System (INIS)

    The overall program objective is to develop and evaluate environmental benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is one or more environmental benign, a.k.a. ''green'' products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter has been to evaluate a number of real world pipeline sources for microbial communities or consortia that form biofilms under laboratory simulations of pipelines. The microorganisms will be identified using classical and molecular microbiological tools and there activities under pipeline simulating conditions will be studied. The quarter saw the collection of the first samples from the industry for isolation of the microorganisms, as well as the design and construction of the laboratory-scale pipeline simulators. Methods development for MIC and biofilm microbial isolations and identification, and laboratory design and construction of pipeline simulators were the only activities. At this stage of the study (first quarter), only preliminary results are available

  11. ENVIRONMENTAL BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    J.R. Paterek; G. Husmillo; V. Trbovic

    2003-01-01

    The overall program objective is to develop and evaluate environmental benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is one or more environmental benign, a.k.a. ''green'' products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter were isolation and cultivation of MIC-causing microorganisms from corroded pipeline samples, optimizing parameters in the laboratory-scale corrosion test loop system and testing the effective concentrations of Capsicum sp. extracts to verify the extent of corrosion on metal coupons by batch culture method. A total of 22 strains from the group of heterotrophic, acid producing, denitrifying and sulfate reducing bacteria were isolated from the gas pipeline samples obtained from Northern Indiana Public Service Company in Trenton, Indiana. They were purified and will be sent out for identification. Bacterial strains of interest were used in antimicrobial screenings and test loop experiments. Parameters for the laboratory-scale test loop system such as gas and culture medium flow rate; temperature; inoculation period; and length of incubation were established. Batch culture corrosion study against Desulfovibrio vulgaris showed that one (S{sub 1}M) out of the four Capsicum sp. extracts tested was effective in controlling the corrosion rate in metal coupons by 33.33% when compared to the untreated group.

  12. ENVIRONMENTAL BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    J.R. Paterek

    2002-03-01

    The overall program objective is to develop and evaluate environmental benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is one or more environmental benign, a.k.a. ''green'' products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter has been to evaluate a number of real world pipeline sources for microbial communities or consortia that form biofilms under laboratory simulations of pipelines. The microorganisms will be identified using classical and molecular microbiological tools and there activities under pipeline simulating conditions will be studied. The quarter saw the collection of the first samples from the industry for isolation of the microorganisms, as well as the design and construction of the laboratory-scale pipeline simulators. Methods development for MIC and biofilm microbial isolations and identification, and laboratory design and construction of pipeline simulators were the only activities. At this stage of the study (first quarter), only preliminary results are available.

  13. ENVIRONMENTALLY BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Paterek; Gemma Husmillo

    2002-07-01

    The overall program objective is to develop and evaluate environmental benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is one or more environmental benign, a.k.a. ''green'' products that can be applied to maintain the structure and dependability of the natural gas infrastructure. Capsicum sp. extracts and pure compounds were screened for their antimicrobial activity against MIC causing bacteria. Studies on the ability of these compounds to dissociate biofilm from the substratum were conducted using microtiter plate assays. Tests using laboratory scale pipeline simulators continued. Preliminary results showed that the natural extracts possess strong antimicrobial activity being comparable to or even better than the pure compounds tested against strains of sulfate reducers. Their minimum inhibitory concentrations had been determined. It was also found that they possess bactericidal properties at minimal concentrations. Biofilm dissociation activity as assessed by microtiter plate assays demonstrated varying degrees of differences between the treated and untreated group with the superior performance of the extracts over pure compounds. Such is an indication of the possible benefits that could be obtained from these natural products. Confirmatory experiments are underway.

  14. ENVIRONMENTALLY BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Paterek; Gemma Husmillo; Amrutha Daram; Vesna Trbovic; Teri Storino

    2003-04-01

    The overall program objective is to develop and evaluate environmentally benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is to develop one or more environmentally benign (a.k.a. ''green'') products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter includes the application of new methods of Capsicum sp. (pepper) extraction by soxhlet method and analysis of a new set of extracts by thin layer chromatography (TLC) and high performance liquid chromatography (HPLC); isolation and cultivation of MIC-causing microorganisms from corroded pipeline samples; and evaluation of antimicrobial activities of the old set of pepper extracts in comparison with major components of known biocides and corrosion inhibitors. Twelve new extracts from three varieties of Capsicum sp. (Serrano, Habanero, and Chile de Arbol) were obtained by soxhlet extraction using 4 different solvents. Results of TLC done on these extracts showed the presence of capsaicin and some phenolic compounds, while that of HPLC detected capsaicin and dihydrocapsaicin peaks. More tests will be done to determine specific components. Additional isolates from the group of heterotrophic, acid-producing, denitrifying and sulfate-reducing bacteria were obtained from the pipeline samples submitted by gas companies. Isolates of interest will be used in subsequent antimicrobial testing and test-loop simulation system experiments. Results of antimicrobial screening of Capsicum sp. extracts and components of known commercial biocides showed comparable activities when tested against two strains of sulfate-reducing bacteria.

  15. Determination of MICs of Aminocandin for Candida spp. and Filamentous Fungi▿

    OpenAIRE

    Isham, N.; Ghannoum, M. A.

    2006-01-01

    Candida and Aspergillus spp., as well as other filamentous molds, have increasingly been reported as the causes of severe invasive fungal infections. We evaluated the new echinocandin aminocandin (AMN) for its antifungal activities against a range of fungal pathogens by determination of the MICs for the organisms. The MICs of the comparator drugs amphotericin B, caspofungin, micafungin, and voriconazole were also determined. The MICs of AMN for 25 strains each of non-Candida albicans Candida ...

  16. Prevention for possible microbiologically influenced corrosion (MIC) in RHLWE flush water system

    International Nuclear Information System (INIS)

    This report is in response to the request to provide a recommendation for the prevention of possible microbiologically influenced corrosion (MIC) for the RHLWE (Replacement High-Level Waste Evaporator) flush water (FW) system. The recent occurrences of MIC at DWPF prompted HLWE to evaluate the possibility of MIC occurring in this 304L stainless steel RHLWE flush water system. Concern was heightened by the fact that the well water used and the other conditions at H-Tank Farm are similar to those at DWPF. However, only one known leak has occurred in the existing 304L evaporator flush water systems in either tank farm (in 1H system), and no MIC Corrosion has been confirmed in the tank farm area. The design of the RHLWE flush water system (completed long before the occurrence of MIC at DWPF) was modeled after the existing evaporator flush water systems and did not specifically include MIC prevention considerations. Therefore, MIC prevention was not specifically considered during the design phase of this flush water system. The system is presently being installed. After an extensive evaluation, a task team concluded that the best biocide to prevent the occurrence of MIC would be NaOH at fairly low concentration. Sodium hydroxide (NaOH) is optimal in this application, because of its effectiveness, low cost, and familiarity to the Operations personnel (see Appendix A). However, it is the opinion of the task group that application should be withheld until MIC corrosion is demonstrated in the system

  17. High-performance computing on the Intel Xeon Phi how to fully exploit MIC architectures

    CERN Document Server

    Wang, Endong; Shen, Bo; Zhang, Guangyong; Lu, Xiaowei; Wu, Qing; Wang, Yajuan

    2014-01-01

    The aim of this book is to explain to high-performance computing (HPC) developers how to utilize the Intel® Xeon Phi™ series products efficiently. To that end, it introduces some computing grammar, programming technology and optimization methods for using many-integrated-core (MIC) platforms and also offers tips and tricks for actual use, based on the authors' first-hand optimization experience.The material is organized in three sections. The first section, "Basics of MIC", introduces the fundamentals of MIC architecture and programming, including the specific Intel MIC programming environment

  18. What Is the Appropriate Meropenem MIC for Screening of Carbapenemase-Producing Enterobacteriaceae in Low-Prevalence Settings?

    Science.gov (United States)

    Fattouh, Ramzi; Tijet, Nathalie; McGeer, Allison; Poutanen, Susan M; Melano, Roberto G; Patel, Samir N

    2016-03-01

    Infection with carbapenemase-producing Enterobacteriaceae (CPE) has been shown to cause significant illness among hospitalized patients. Given the paucity of treatment options, there is a critical need to stop the spread of CPE. However, screening for the presence of CPE in laboratory settings has been challenging. In order to assess the effectiveness of current CPE detection guidelines, we analyzed the meropenem MIC distribution for a large set of clinical Enterobacteriaceae isolates. A total of 1,022 isolates submitted to the Public Health Ontario Laboratories (PHOL) from January 2011 to March 2014 were examined. Only isolates displaying a meropenem or ertapenem MIC of ≥ 0.25 or ≥ 1 μg/ml, respectively, were included. Carbapenemase-positive isolates were identified by multiplex PCR. We identified 189 isolates positive for carbapenemases, which primarily comprised NDM, KPC, and OXA-48-like carbapenemases, and these isolates were largely Klebsiella spp., Escherichia coli, and Enterobacter spp. Interestingly, 14 to 20% of these isolates displayed meropenem MICs within the susceptible range on the basis of CLSI and EUCAST breakpoint interpretive criteria. While the majority of meropenem-susceptible CPE isolates were observed to be E. coli, meropenem susceptibility was not exclusive to any one species/genus or carbapenemase type. Application of CLSI screening recommendations captured only 86% of carbapenemase-producing isolates, whereas application of EUCAST recommendations detected 98.4% of CPE isolates. In a region with a low carbapenemase prevalence, meropenem-based screening approaches require a cutoff MIC near the epidemiological wild-type threshold in order to achieve nearly optimal CPE identification. PMID:26711746

  19. Correlation of MIC with Outcome for Candida Species Tested against Caspofungin, Anidulafungin, and Micafungin: Analysis and Proposal for Interpretive MIC Breakpoints▿

    OpenAIRE

    Pfaller, M A; Diekema, D. J.; Ostrosky-Zeichner, L.; Rex, J H; Alexander, B. D.; Andes, D.; Brown, S D; Chaturvedi, V.; Ghannoum, M A; Knapp, C C; Sheehan, D. J.; Walsh, T J

    2008-01-01

    The CLSI Antifungal Subcommittee followed the M23-A2 “blueprint” to develop interpretive MIC breakpoints for anidulafungin, caspofungin, and micafungin against Candida species. MICs of ≤2 μg/ml for all three echinocandins encompass 98.8 to 100% of all clinical isolates of Candida spp. without bisecting any species group and represent a concentration that is easily maintained throughout the dosing period. Data from phase III clinical trials demonstrate that the standard dosing regimens for eac...

  20. An accelerated electrochemical MIC test for stainless alloys

    International Nuclear Information System (INIS)

    Previous work in our laboratory and elsewhere has suggested that microbially influenced corrosion (MIC) of stainless steels and nickel-base alloys occurs in locally anaerobic regions that support the growth of sulfate-reducing bacteria (SRB). The cathodic reaction is provided by oxygen reduction at remote sites. Such a coupling between anode and cathode is difficult to reproduce in the laboratory, but can be simulated indirectly using a double electrochemical cell, as in previous work. A more realistic simulation using a single aerated electrochemical cell has now been developed, in which a second organism (P. aeruginosa) is used to provide an anoxic habitat for SRB growth and possible a source of organic carbon, within a layer of silt. A bare alloy electrode is used as the oxygen cathode. Tests of this kind using rigorous microbiological procedures have generated pitting corrosion of several alloys in low chloride media simulating freshwater heat exchanger conditions. This report discusses the adaption of these procedures to study corrosion of nuclear waste containers. (author). 20 refs., 2 tabs., 7 figs

  1. Coherent Photon Mapping on the Intel MIC Architecture

    Institute of Scientific and Technical Information of China (English)

    Chun-Meng Kang; Lu Wang; Pei Wang; Yan-Ning Xu; Xiang-Xu Meng

    2015-01-01

    Photon mapping is a global illumination algorithm which is composed of two steps: photon tracing and photon searching. During photon searching step, each shading point needs to search the photon-tree to find k-neighbouring photons for reflected radiance estimation. As the number of shading points and the size of photon-tree are dramatically large, the photon searching step is time consuming. We propose a parallel photon searching algorithm by using radiance estimation approach for coherent shading points on the Intelr Many Integrated Core (MIC) Architecture. In order to efficiently use single instruction multiple data (SIMD) units, shading points are clustered by similarity first (every cluster contains 16 shading-points), and an initial neighbouring scope is searched from the photon-tree for each cluster. Then we use 16-wide SIMD units by performing k-NN searching from the initial neighbouring scope for those 16 shading-points in a cluster in parallel. We use the method to simulate some global illumination scenes on Intelr Xeonr processors and Intelr Xeonr PhiTM coprocessors. The comparison results with existing photon mapping techniques indicate that our method gives significant improvement in speed with the same accuracy.

  2. ENVIRONMENTAL BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    J.R. Paterek; G. Husmillo

    2002-11-01

    The overall program objective is to develop and evaluate environmental benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is one or more environmental benign, a.k.a. ''green'' products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter were monitoring the development of Desulfovibrio species biofilm using the continuous flow cell system, evaluation of pepper compounds by microtiter plate assay for mitigating and inhibiting biofilm formation, and testing the effective concentrations to verify the extent of corrosion on metal coupons. Biofilm formation of Desulfovibrio vulgaris and D. desulfuricans was monitored and documented over a 7-day period. The use of a continuous flow cell system proved to be efficient and non-destructive in studying biofilm growth. Live/Dead BacLight was an efficient stain to determine cell viability. The extracts showed 9-25% biofilm formation inhibition against the two organisms, and 18-19% activity in detaching the already formed biofilm. Preliminary data were obtained on the extent of corrosion of metal coupons when treated with pepper extracts as against the untreated ones. Confirmatory tests are underway. A presentation was prepared and give at the US DOE NETL meeting on gas and petroleum infrastructure. The presentation is include as an addition to this report.

  3. 基于参考点的大规模本体分块与映射%Anchor-based large-scale ontologies partitioning and mapping

    Institute of Scientific and Technical Information of China (English)

    赖雅; 王润梅; 徐德智

    2013-01-01

    In order to solve the problem of low precision and low recall of large-scale ontology partitioning and mapping, this paper proposed a new anchor-based large-scale ontology partitioning and mapping method. This method used anchors to guide partitioning, and partitioned the two ontologies at the same time, which called co-clustering. Firstly,it preprocessed the two ontologies in order to normalize the entities' s name and turn them into tree structure, then used some simple methods to find anchors. At last, the anchors acted cluster centers to cluster the concepts in both ontology trees, and found block mappings at the same time. Theoretical analysis and experimental results show that this method both solves the large-scale ontologeis mapping problem and achieves good precision and recall.%针对大规模本体映射中存在查全率和查准率不高的问题,提出了一种新的基于参考点的大规模本体分块与映射的方法.该方法的主要思想是用参考点来指导分块,并同时对待映射的两个大规模本体同时分块,即联合分块.首先对大规模本体进行预处理,将本体中的实体名称归一化并将其表示成本体树的形式,然后采用一些简便的方法找到参考点,最后以参考点为聚类中心对两个本体树的概念进行聚类,并同时实现块映射.理论分析和实验结果表明,该方法能够有效地解决大规模本体映射问题,并能获得较好的查全率和查准率.

  4. ENVIRONMENTALLY BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    John J. Kilbane II; William Bogan

    2004-01-31

    The overall program objective is to develop and evaluate environmentally benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is to develop one or more environmentally benign (a.k.a. ''green'') products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter included the fractionation of extracts prepared from several varieties of pepper plants, and using several solvents, by high performance liquid chromatography (HPLC). A preliminary determination of antimicrobial activities of the new extracts and fractions using a growth inhibition assay, and evaluation of the extracts ability to inhibit biofilm formation was also performed. The analysis of multiple extracts of pepper plants and fractions of extracts of pepper plants obtained by HPLC illustrated that these extracts and fractions are extremely complex mixtures of chemicals. Gas chromatography-mass spectrometry was used to identify the chemical constituents of these extracts and fractions to the greatest degree possible. Analysis of the chemical composition of various extracts of pepper plants has illustrated the complexity of the chemical mixtures present, and while additional work will be performed to further characterize the extracts to identify bioactive compounds the focus of efforts should now shift to an evaluation of the ability of extracts to inhibit corrosion in mixed culture biofilms, and in pure cultures of bacterial types which are known or believed to be important in corrosion.

  5. Determination Of Appropriate Antibiotic In Bacterial Meningitis Of Children Based On MIC

    Directory of Open Access Journals (Sweden)

    Noorbakhsh S

    2005-05-01

    Full Text Available Background: Bacterial meningitis is one of the most serious infections in infants and children. Three organisms include S.Pneumo;N.mening;H.Influ are the most common cause of meningitis in children between 2M-14y age.Etest is a new method for determination the MIC of some antimicrobial drugs in agarose .This method is useful for some organisms like as S .Pneumo; N.mening; H.Influ;sensitive Streptococcus and anaerobic ;aerobic gram negative. Materials and Methods: In this descriptive cross sectional study; In 57 suspected meningitis children ; organisms isolated from blood; CSF or other sterile boy fluid after culturing and antibiogram;. .MIC of someorganisms detected by Etest method. Results: Streptococcuswas the most prevalent ( 70% and S.pneumon( 90% of all Streptococcus; H.infl 2%;N.mening 4%and L.monocyt 6%(more than expected;Gram negative (Ecoli; Klebsiella; entrobacter and psudomona 18%. There was significant difference (P =0.01in type of organisms between age groups. S.pneumonia was more frequent in children > 2 year ;N.meningitis in>4yr old .Site of isolation :blood; CSF (35.8*;28.3%other sterile site 18.4%;concomitant positive culture in two site:17%.Mean age in Streptococcus was significantly different with Listeria (p=0.05; N.meningitis (p=0.04;H.influ (p=0.04;.but no difference with Staphylococcus;Klebsiella and E.coli Two type of H.inf were sensitive to Ampici or chloram ;both of them were sensitive to ceftiaxon. GBS were sensitive to PNC or Ampici Strep.nonAnonBnon- Cotrimoxazol>32mic/ml /PNC >256mic/ml/ Vanco>256mic/ml Strep.D: Cotrimoxazol>0.062mg/ml/ /PNC >0.016mic/ml/Imipenem>0.032mic/ml. Strep Pneumonia: All fo them were sensitive except 3 cases /Cotrimoxazol>2ic/ml /PNC =0.01mic/ml/Vanco>0.125mic/ m Vanco>0. 25mic/ ml/.Cotrimoxazol>2ic/ml / PNC =0.01mg/ml Vanco>0.125mic/ ml / Cotrimoxazol>2mic/ml /MIC-PNC >0.016mic/ml Therefore high dose of PNC is adequate for S.pneu ;because of Interm resistance to PNC All 3 N.menin were

  6. ENVIROMENTALLY BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Paterek; Gemma Husmillo; Amrutha Daram; Vesna Trbovic

    2003-10-31

    The overall program objective is to develop and evaluate environmentally benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is to develop one or more environmentally benign (a.k.a. ''green'') products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter includes the application of the method of fractionation of the extracts by high performance liquid chromatography (HPLC); determination of antimicrobial activities of the new extracts and fractions using a growth inhibition assay, and evaluation of the extracts' ability to inhibit biofilm formation. We initiated the delivery system for these new biocides in the test cell and in mixtures of foam components and biocides/anti-biofilms. A total of 51 fractions collected by HPLC from crude extracts that were obtained from three varieties of Capsicum sp. (Serrano, Habanero, Chile de Arbol) were subjected to growth inhibition tests against two SRB strains, D. vulgaris and D. desulfuricans. Five fractions showed growth inhibition against both strains while seven inhibited D. desulfuricans only. The crude extracts did not show growth inhibition on both strains but were proven to be potent in preventing the formation of biofilm. Growth inhibition tests of the same set of crude extracts against Comamonas denitrificans did not show positive results. The fractions will be subjected to biofilm inhibition and dissociation assay as well. The delivery system to be evaluated first was foam. The ''foam pig'' components of surfactants and water were tested with the biocide addition. The first chemical and physical parameters to be tested were pH and surfactants. Tests using the fractionated pepper extracts are progressing rapidly. Gas chromatographic analysis

  7. MIC: Magnetically Deployable Structures for Power, Propulsion, Processing, Habitats and Energy Storage at Manned Lunar Bases

    Science.gov (United States)

    Powell, James; Maise, George; Paniagua, John; Rather, John

    2007-01-01

    MIC (Magnetically Inflated Cables) is a new approach for robotically erecting very large, strong, rigid, and ultra-lightweight structures in space. MIC structures use a network of high current (SC) cables with attached high tensile strength Kevlar or Spectra tethers. MIC is launched as a compact package of coiled SC cables and tethers on a conventional launch vehicle. Once in space the SC cables are electrically energized. The resultant strong outwards magnetic forces expand them and the restraining tethers into a large structure, which can be 100's of meters in size. MIC structures can be configured for many different applications, including solar electric generation, solar thermal propulsion, energy storage, large space telescopes, magnetic shielding for astronauts, etc. The MIC technology components, including high temperature superconductors (HTS), thermal insulation, high strength tethers, and cryogenic refrigerators all exist commercially. Refrigeration requirements are very modest, on the order of 100 watts thermal per kilometer of MIC cable, with an input electric power to the refrigeration system of ~5 kW(e) per km. baseline MIC designs are described for a manned lunar base, including: 1) a 1 MW(e) solar electric system, 2) a high Isp (~900 seconds) solar thermal tug to transport 30 ton payloads between the Earth and the Moon, 3) a 2000 Megajoule electric energy storage system for peaking and emergency power, and 4) a large (~1 km) space telescope.

  8. MIC-Large Scale Magnetically Inflated Cable Structures for Space Power, Propulsion, Communications and Observational Applications

    Science.gov (United States)

    Powell, James; Maise, George; Rather, John

    2010-01-01

    A new approach for the erection of rigid large scale structures in space-MIC (Magnetically Inflated Cable)-is described. MIC structures are launched as a compact payload of superconducting cables and attached tethers. After reaching orbit, the superconducting cables are energized with electrical current. The magnet force interactions between the cables cause them to expand outwards into the final large structure. Various structural shapes and applications are described. The MIC structure can be a simple flat disc with a superconducting outer ring that supports a tether network holding a solar cell array, or it can form a curved mirror surface that concentrates light and focuses it on a smaller region-for example, a high flux solar array that generates electric power, a high temperature receiver that heats H2 propellant for high Isp propulsion, and a giant primary reflector for a telescope for astronomy and Earth surveillance. Linear dipole and quadrupole MIC structures are also possible. The linear quadrupole structure can be used for magnetic shielding against cosmic radiation for astronauts, for example. MIC could use lightweight YBCO superconducting HTS (High Temperature Superconductor) cables, that can operate with liquid N2 coolant at engineering current densities of ~105 amp/cm2. A 1 kilometer length of MIC cable would weigh only 3 metric tons, including superconductor, thermal insulations, coolant circuits, and refrigerator, and fit within a 3 cubic meter compact package for launch. Four potential MIC applications are described: Solar-thermal propulsion using H2 propellant, space based solar power generation for beaming power to Earth, a large space telescope, and solar electric generation for a manned lunar base. The first 3 applications use large MIC solar concentrating mirrors, while the 4th application uses a surface based array of solar cells on a magnetically levitated MIC structure to follow the sun. MIC space based mirrors can be very large and light

  9. Determination of pyrazinamide MICs for Mycobacterium tuberculosis at different pHs by the radiometric method.

    OpenAIRE

    Salfinger, M; Heifets, L. B.

    1988-01-01

    The MICs of pyrazinamide (PZA) were determined for Mycobacterium tuberculosis cultivated under different pH conditions in 7H12 liquid medium. Mycobacterial growth was monitored by the radiometric method (BACTEC system; Johnston Laboratories, Inc., Towson, Md.). We observed a predictable eightfold difference between the MICs determined at pH 5.5 and those determined at pH 5.95. The highest MICs for 21 susceptible strains were 50.0 micrograms/ml at pH 5.5 and 400 micrograms/ml at pH 5.95. This ...

  10. Influence of Water Pollution on MIC of Stainless Steel 304L

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The influence of water pollution and welding defects on MIC (microbiologically influenced corrosion) was studied. The open circuit potential (OCP) was measured during MIC test. It was found that OCP shifted to a higher level when the system was inoculated with bacteria while the OCP of those samples in water without bacteria was kept at a low level. The OCP decreased dramatically when MIC started in polluted water. Combination of weld defect-heat tint, polluted water and adding bacteria causes MIC happen at high rate. Some elements inside the tubercle were analyzed with EDXA. The pits and biofilm were observed with SEM. Microbiological analysis revealed the difference of bacteria between corroded and uncorroded samples.

  11. Epidemiological cut-off values for Flavobacterium psychrophilum MIC data generated by a standard test protocol

    DEFF Research Database (Denmark)

    Smith, P.; Endris, R.; Kronvall, G.;

    2016-01-01

    Epidemiological cut-off values were developed for application to antibiotic susceptibility data for Flavobacterium psychrophilum generated by standard CLSI test protocols. The MIC values for ten antibiotic agents against Flavobacterium psychrophilum were determined in two laboratories. For five...

  12. Guidelines for destructive examination of potential MIC [microbiologically influenced corrosion]-related failures

    International Nuclear Information System (INIS)

    Microbiologically influenced corrosion (MIC) is recognized as a major cause of pitting corrosion failures in natural waters. In order to alleviate the problem, it is important to establish the exact cause of corrosion. If there is a possibility that the failure is due to MIC, a particularly careful failure analysis must be conducted. MIC can be misdiagnosed as attack due to conventional chloride crevice/pitting corrosion unless specialized techniques are used. Certain techniques generally must be employed, including a careful visual examination, is situ bacterial sampling of residual water, bacterial analysis for corrosion products, radiographic examinations, and metallographic examinations. Other techniques may be necessary, or may be very helpful in the analysis, including culture growth, scanning electron microscopy, and ultrasonic examinations. Metallographic examinations can reveal MIC characteristics such as selective pitting of one phase in duplex stainless steel weldments. The methods of failure analysis and their importance are addressed, including each of the steps in the nondestructive examinations and destructive analyses

  13. In Vitro Selection of Neisseria gonorrhoeae Mutants with Elevated MIC Values and Increased Resistance to Cephalosporins

    OpenAIRE

    Johnson, S. R.; Grad, Yonatan Hagai; Ganakammal, S. R.; Burroughs, M; Frace, M.; Lipsitch, Marc; Weil, R.; Trees, D.

    2014-01-01

    Strains of Neisseria gonorrhoeae with mosaic penA genes bearing novel point mutations in penA have been isolated from ceftriaxone treatment failures. Such isolates exhibit significantly higher MIC values to third-generation cephalosporins. Here we report the in vitro isolation of two mutants with elevated MICs to cephalosporins. The first possesses a point mutation in the transpeptidase region of the mosaic penA gene, and the second contains an insertion mutation in pilQ.

  14. In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins.

    Science.gov (United States)

    Johnson, Steven R; Grad, Yonatan; Ganakammal, Satishkumar Ranganathan; Burroughs, Mark; Frace, Mike; Lipsitch, Marc; Weil, Ryan; Trees, David

    2014-11-01

    Strains of Neisseria gonorrhoeae with mosaic penA genes bearing novel point mutations in penA have been isolated from ceftriaxone treatment failures. Such isolates exhibit significantly higher MIC values to third-generation cephalosporins. Here we report the in vitro isolation of two mutants with elevated MICs to cephalosporins. The first possesses a point mutation in the transpeptidase region of the mosaic penA gene, and the second contains an insertion mutation in pilQ. PMID:25199775

  15. Parametric-time coherent states for the generalized MIC-Kepler system

    International Nuclear Information System (INIS)

    In this study, we construct the parametric-time coherent states for the negative energy states of the generalized MIC-Kepler system, in which a charged particle is in a monopole vector potential, a Coulomb potential, and a Bohm-Aharonov potantial. We transform the system into four isotropic harmonic oscillators and construct the parametric-time coherent states for these oscillators. Finally, we compactify these states into the physical time coherent states for the generalized MIC-Kepler system

  16. Development of biological coal gasification (MicGAS Process). Eighth quarterly report

    Energy Technology Data Exchange (ETDEWEB)

    1992-07-28

    This report describes progress on three fronts of the project. First in studies to elucidate optimal growing conditions for the consortia of coal degraders employed indicates that best growth occurs with 0. 2% w/v Shefton T. Secondly in comparing the biodegradative properties of the coal degraders, isolates identified as Mic-1 and Mic-4 were the best performers. And lastly bioreactors studies in batch mode are related.

  17. Microbially influenced corrosion (MIC) of metal welds. Kinzoku yosetsubu no biseibutsu fushoku

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, Y.; Matsuda, F. (Osaka Univ., Osaka (Japan). Welding Research Inst.)

    1993-06-20

    There is a microbially influenced corrosion (MIC) as one of the relations between the microorganism (bacteria) and the metal engineering. The corrosion accidents, which have been regarded as caused by MIC, have recently occurred in the petrochemical industry, gas industry, energy plant and so forth, and consequently the damage of structures has become to be the circumstances which were not negligible. It has been understood that the welds have a close relation out of the causes. The MIC advances with a very high speed under an existence of the microorganisms when the environmental conditions are satisfied, and even a value of about 0.57 nm/S (18 mm/year) is presumed in an example of SUS304 steel welds. In spite of defects, which were originally caused by the corrosion, there is a possibility that they were judged by mistake as caused by the weld imperfection. The MIC has a close relation with the plural disciplines such as the microbiology, material engineering, corrosion engineering, welding engineering, joining engineering and so forth. In this paper, the cases of MIC in the stainless steel welds, the kind of microorganisms which cause the MIC and the countermeasures agsinst them are outlined. 9 refs., 6 figs.

  18. Alterations of Penicillin-Binding Proteins 1A, 2X, and 2B in Streptococcus pneumoniae Isolates for Which Amoxicillin MICs Are Higher than Penicillin MICs

    OpenAIRE

    Kosowska, K.; Jacobs, M R; Bajaksouzian, S.; Koeth, L.; Appelbaum, P. C.

    2004-01-01

    Penicillin-binding proteins (PBPs) of 15 selected penicillin- and amoxicillin-resistant Streptococcus pneumoniae isolates (MICs of 2 to 8 and 8 to 16 μg/ml, respectively) were studied. In addition to typical changes in PBPs 1A and 2X, these strains had 10 unique changes in PBP 2B, including a 618A-G substitution, which may be the key alteration associated with amoxicillin resistance.

  19. Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone.

    Science.gov (United States)

    Van Laar, Victor S; Berman, Sarah B; Hastings, Teresa G

    2016-07-01

    Mitochondrial dysfunction has been implicated in Parkinson's disease (PD) neuropathology. Mic60, also known as mitofilin, is a protein of the inner mitochondrial membrane and a key component of the mitochondrial contact site and cristae junction organizing system (MICOS). Mic60 is critical for maintaining mitochondrial membrane structure and function. We previously demonstrated that mitochondrial Mic60 protein is susceptible to both covalent modification and loss in abundance following exposure to dopamine quinone. In this study, we utilized neuronally-differentiated SH-SY5Y and PC12 dopaminergic cell lines to examine the effects of altered Mic60 levels on mitochondrial function and cellular vulnerability in response to PD-relevant stressors. Short hairpin RNA (shRNA)-mediated knockdown of endogenous Mic60 protein in neuronal SH-SY5Y cells significantly potentiated dopamine-induced cell death, which was rescued by co-expressing shRNA-insensitive Mic60. Conversely, in PC12 and SH-SY5Y cells, Mic60 overexpression significantly attenuated both dopamine- and rotenone-induced cell death as compared to controls. Mic60 overexpression in SH-SY5Y cells was also associated with increased mitochondrial respiration, and, following rotenone exposure, increased spare respiratory capacity. Mic60 knockdown cells exhibited suppressed respiration and, following rotenone treatment, decreased spare respiratory capacity. Mic60 overexpression also affected mitochondrial fission/fusion dynamics. PC12 cells overexpressing Mic60 exhibited increased mitochondrial interconnectivity. Further, both PC12 cells and primary rat cortical neurons overexpressing Mic60 displayed suppressed mitochondrial fission and increased mitochondrial length in neurites. These results suggest that altering levels of Mic60 in dopaminergic neuronal cells significantly affects both mitochondrial homeostasis and cellular vulnerability to the PD-relevant stressors dopamine and rotenone, carrying implications for PD

  20. Dynamic Ni gettered by PSG from S-MIC poly-Si and its TFTs

    International Nuclear Information System (INIS)

    A dynamic phosphor-silicate glass (PSG) gettering method is proposed in which the processes of the gettering of Ni by PSG and the crystallizing of α-Si into poly-Si by Ni take place simultaneously. The effects of PSG gettering process on the performances of solution-based metal induced crystallized (S-MIC) poly-Si materials and their thin film transistors (TFTs) are discussed. The crystallization rate is much reduced due to the fact that the Ni as a medium source of crystallization is extracted by the PSG during crystallization at the same time. The boundary between two neighbouring grains in S-MIC poly-Si with PSG looks blurrier than without PSG. Compared with the TFTs made from S-MIC poly-Si without PSG gettering, the TFTs made with PSG gettering has a reduced gate induced leakage current

  1. Dynamic Ni gettered by PSG from S-MIC poly-Si and its TFTs

    Institute of Scientific and Technical Information of China (English)

    Meng Zhi-Guo; Li Yang; Wu Chun-Ya; Zhao Shu-Yun; Li Juan; Man Wong; Hoi Sing-Kwok; Xiong Shao-Zhen

    2008-01-01

    A dynamic phosphor-silicate glass (PSG) gettering method is proposed in which the processes of the gettering of Ni by PSG and the crystallizing of á-Si into poly-Si by Ni take place simultaneously. The effects of PSG gettering process on the performances of solution-based metal induced crystallized (S-MIC) poly-Si materials and their thin film transistors (TFTs) are discussed. The crystallization rate is much reduced due to the fact that the Ni as a medium source of crystallization is extracted by the PSG during crystallization at the same time. The boundary between two neighbouriug grains in S-MIC poly-Si with PSG looks blurrier than without PSG. Compared with the TFTs made from S-MIC poly-Si without PSG gettering, the TFTs made with PSG gettering has a reduced gate induced leakage current.

  2. El cómic en España: 1977-2007

    Directory of Open Access Journals (Sweden)

    Pablo Vergara Díaz

    2009-07-01

    Full Text Available Este artículo pretende repasar las tres últimas décadas del cómic en España. El estudio se realiza valorando la evolución de la industria del cómic, desde sus inicios durante la dictadura y su expansión con la llegada de la democracia hasta la época actual de dificultades y cambios. El auge del cómic se observa en su relevancia creciente dentro de la prensa, en la aceptación de un público que va madurando con el paso del tiempo y, sobre todo, en las ventas de una industria que tiene que adaptarse a nuevas situaciones.

  3. Effect of Percolation on Structural and Electrical Properties of MIC Processed SiGe/Al Multilayers

    Science.gov (United States)

    Lindorf, M.; Rohrmann, H.; Span, G.; Albrecht, M.

    2016-03-01

    The effect of metal induced crystallization (MIC) is widely used in the production of electronic devices by forming large grained polycrystalline Si from amorphous Si in contact with Al. This effect can also be utilized in conjunction with silicon-germanium (SiGe) alloys and thus provides means of a possible low cost production of future high temperature thermoelectric devices. In this work, sputter deposited multilayer systems of Si80Ge20/Al thin films have been investigated. The effect of MIC is used to crystallize the initially amorphous SiGe while simultaneously doping it with Al. As metallic phases would be detrimental to the thermoelectric performance, special interest is directed to the Al layers and their dissociation during the annealing treatment. A percolation limit regarding the thickness and continuity of the Al layers was found, but no detrimental side effects with respect to the MIC process could be detected.

  4. En el umbral. El cómic español contemporáneo

    Directory of Open Access Journals (Sweden)

    García, Santiago

    2011-09-01

    Full Text Available These days, when we talk about contemporary Spanish comics, or comics produced primarily in Spain for the Spanish market, we have to contemplate two main trends: the graphic novel and the humor comics. The fall of the traditional industry opened the door to the realization of authoral ambitions that previous generations of artists couldn’t fulfil.

    En la actualidad, cuando hablamos de cómic español contemporáneo, es decir, cuando nos referimos a cómics producidos en España y para el mercado español en primer lugar, tenemos que tener en cuenta dos corrientes principalmente: la novela gráfica y el cómic de humor. La caída de la industria tradicional ha abierto el camino para que se cumplan las aspiraciones autorales que durante décadas tuvieron muchos dibujantes españoles.

  5. The "Binarity and Magnetic Interactions in various classes of Stars" (BinaMIcS) project

    OpenAIRE

    Neiner, C.; Morin, J.; Alecian, E.; collaboration, the BinaMIcS

    2015-01-01

    The "Binarity and Magnetic Interactions in various classes of stars" (BinaMIcS) project is based on two large programs of spectropolarimetric observations with ESPaDOnS at CFHT and Narval at TBL. Three samples of spectroscopic binaries with two spectra (SB2) are observed: known cool magnetic binaries, the few known hot magnetic binaries, and a survey sample of hot binaries to search for additional hot magnetic binaries. The goal of BinaMIcS is to understand the complex interplay between stell...

  6. El discurso interior en los cómics de Frank Miller

    OpenAIRE

    Pérez García, Juan Carlos

    2012-01-01

    Des dels anys vuitantes, Frank Miller ha estat reconegut com un dels principals renovadors del comic book produït per la industria nordamericana. Un dels seus trets d’estil més distintius i influents és el tractament del discurs interior dels personatges, inspirat per la novel·la hard-boiled i el cinema negre americans, però també per còmics previs, de crim i de superherois. En aquest article comentem els diversos usos del discurs interior en els còmics de Miller amb casos d’estudi elegits de...

  7. Traducción de cómic americano, superhéroes y chimichangas

    OpenAIRE

    Gonzalbes Valenzuela, Carla

    2015-01-01

    El objetivo de este trabajo es estudiar el proceso de traducción de un cómic americano. Consiste de una traducción de varios fragmentos de un cómic de Marvel de Masacre (Deadpool, en inglés) y un posterior análisis de dicha traducción, en el que se comentan los problemas que han surgido, se explica la solución al problema y se justifican las decisiones tomadas

  8. Anti-MIC2 as a tool in examination of testicular biopsies

    DEFF Research Database (Denmark)

    Visfeldt, J; Cortes, D; Thorup, J M;

    1999-01-01

    is recommended in order to evaluate future fertility potential. The spermatogonia are identified on histological sections and the number per tubular transverse section is compared with normal values for age. The patient is at 33-100% risk of subsequent infertility when the number of spermatogonia per...... palpable testes which had been cultured in vitro for 7, 14 or 21 days. In all cases the immunohistochemical method with DAKO antibody to the MIC2 gene product was helpful for identification of Sertoli cells and germ cells, and we therefore recommend the use of anti-MIC2 in all testicular biopsies where it...

  9. Coneixements previs i rendiment acadèmic a la Universitat

    OpenAIRE

    García Gay, Lourdes

    1999-01-01

    CONEIXEMENTS PREVIS I RENDIMENT ACADÈMIC A LA UNIVERSITATAdoptant el model del constructivisme, la tesi es proposa com a objectiu esbrinar quina és la base acadèmica de l'alumnat en arribar als estudis universitaris de Fisioteràpia i comprovar si aquesta base influeix en el rendiment acadèmic durant el primer curs de la carrera.La tesi està estructurada en dues parts. En la fonamentació teòrica cal considerar el context en què se situa la tesi (canvi del sistema educatiu, renovació de les PAA...

  10. Anàlisi econòmic d'una virtual power plant

    OpenAIRE

    Palma Martí, Narcís

    2014-01-01

    En el present treball es simula una Virtual Power Plant (VPP) per analitzar-ne els aspectes econòmics, fundamentalment mitjançant el Levelized Cost of Energy (LCOE). En primer lloc es presenten les diferents generacions distribuïdes que posteriorment formaran part de la VPP i es defineix el concepte VPP. Es mostra també la metodologia usada pels anàlisis econòmics de generació elèctrica. Posteriorment es presenta el software PowerWorld® que serà usat per la simulació. En la part final, es ...

  11. [Aberration corrected intraocular lens for microincision cataract surgery (MICS). Intraindividual comparison with a conventional lens - 1-year follow-up].

    Science.gov (United States)

    Möglich, M; Häberle, H; Pham, D T; Wirbelauer, C

    2009-10-01

    Microincision cataract surgery (MICS) is an important advancement in the field of cataract surgery. This article compares an aberration corrected hydrophilic acrylic intraocular lens (IOL) having a hydrophobic surface for MICS with a one-piece hydrophobic acrylic IOL with respect to capsule sac stability, image quality, and after-cataract formation over the course of 1 year. The operations were performed as bimanual MICS or coaxial phacoemulsification. Overall the results after implantation of the IOL by MICS can be regarded as positive in comparison to the standard operation. PMID:18836727

  12. Assessing the Accuracy of High Resolution Digital Surface Models Computed by PhotoScan® and MicMac® in Sub-Optimal Survey Conditions

    Directory of Open Access Journals (Sweden)

    Marion Jaud

    2016-06-01

    Full Text Available For monitoring purposes and in the context of geomorphological research, Unmanned Aerial Vehicles (UAV appear to be a promising solution to provide multi-temporal Digital Surface Models (DSMs and orthophotographs. There are a variety of photogrammetric software tools available for UAV-based data. The objective of this study is to investigate the level of accuracy that can be achieved using two of these software tools: Agisoft PhotoScan® Pro and an open-source alternative, IGN© MicMac®, in sub-optimal survey conditions (rugged terrain, with a large variety of morphological features covering a range of roughness sizes, poor GPS reception. A set of UAV images has been taken by a hexacopter drone above the Rivière des Remparts, a river on Reunion Island. This site was chosen for its challenging survey conditions: the topography of the study area (i involved constraints on the flight plan; (ii implied errors on some GPS measurements; (iii prevented an optimal distribution of the Ground Control Points (GCPs and; (iv was very complex to reconstruct. Several image processing tests are performed with different scenarios in order to analyze the sensitivity of each software package to different parameters (image quality, numbers of GCPs, etc.. When computing the horizontal and vertical errors within a control region on a set of ground reference targets, both methods provide rather similar results. A precision up to 3–4 cm is achievable with these software packages. The DSM quality is also assessed over the entire study area comparing PhotoScan DSM and MicMac DSM with a Terrestrial Laser Scanner (TLS point cloud. PhotoScan and MicMac DSM are also compared at the scale of particular features. Both software packages provide satisfying results: PhotoScan is more straightforward to use but its source code is not open; MicMac is recommended for experimented users as it is more flexible.

  13. MIC3 over-expression reduces cotton susceptibility to root-knot nematode

    Science.gov (United States)

    The inheritance of root-knot nematode (RKN) resistance in cotton has been the focus of much research; however, the mechanism of the resistance at the molecular level remains largely unknown. To date, increased transcript and protein levels of MIC3 in galls of resistant plants remains the only examp...

  14. Luces y sombras de la amazona de cómic Wonder Woman, la Mujer Maravilla

    OpenAIRE

    Marfil Díaz, María Inmaculada Concepción

    2014-01-01

    La mujer constituye una parte determinante que sustenta el tejido social de todas las culturas y, sin embargo, no ha sido protagonista principal en el mundo del cómic de superhéroes. Pero hay excepciones, como Wonder Woman, la Mujer Maravilla. ¿Qué

  15. Study of MIC impact in a full-scale ship ballast tank

    NARCIS (Netherlands)

    Heyer, A.; Mol, J.M.C.; D'Souza, F.; Wit, J.H.W. de; Ferrari, G.

    2012-01-01

    Microbiologically influenced corrosion (MIC) of steel is a serious problem in the marine environment and many industries, such as the shipping industry. While electrochemical measurements such as impedance have been used in corrosion monitoring for several years, the true capabilities of the techniq

  16. MILLIMETER EMISSION STRUCTURE IN THE FIRST ALMA IMAGE OF THE AU Mic DEBRIS DISK

    NARCIS (Netherlands)

    MacGregor, Meredith A.; Wilner, David J.; Rosenfeld, Katherine A.; Andrews, Sean M.; Matthews, Brenda; Hughes, A. Meredith; Booth, Mark; Chiang, Eugene; Graham, James R.; Kalas, Paul; Kennedy, Grant; Sibthorpe, Bruce

    2013-01-01

    We present 1.3 mm ALMA Cycle 0 observations of the edge-on debris disk around the nearby, similar to 10 Myr old, M-type star AU Mic. These observations obtain 0 ''.6 (6 AU) resolution and reveal two distinct emission components: (1) the previously known dust belt that extends to a radius of 40 AU an

  17. Sin City: cuando el cine se rinde a los pies del cómic

    OpenAIRE

    Echazarreta Soler, Carmen

    2006-01-01

    Proposta didàctica que se situa entre els llenguatges del còmic i del cinema per a promoure la reflexió sobre la cerca de noves formes de narrar. El fil conductor és Sin City i es proposen, també, 10 activitats per als alumnes

  18. Correlation of MIC value and disk inhibition zone diameters in clinical Legionella pneumophila serogroup 1 isolates

    NARCIS (Netherlands)

    Bruin, J.P. de; Diederen, B.M.; Ijzerman, E.P.; Boer, J.W. den; Mouton, J.W.

    2013-01-01

    OBJECTIVES: Routine use of disk diffusion tests for detecting antibiotic resistance in Legionella pneumophila has not been described. The goal of this study was to determine the correlation of MIC values and inhibition zone diameter (MDcorr) in clinical L. pneumophila isolates. METHODS: Inhibition z

  19. Molecular Evolution of Clustered MIC-3 (Meloidogyne Induced Cotton -3) Multigene Family of Gossypium Species

    Science.gov (United States)

    Uniqueness, content, localization, and defense-related features of the root-knot nematode resistance-associated MIC-3 multigene cluster in the genus Gossypium are all of interest for molecular evolutionary studies of duplicate genes in allopolyploids. Here we report molecular evolutionary rates of t...

  20. Spectrophotometric Determination of Microamounts of Uranium previous Extraction with TBP-MIC

    International Nuclear Information System (INIS)

    Selective extraction of uranium in nitric acid medium with a mixture of Tbp-MIC (1:10) has been achieved. Aluminium nitrate was used as salting agent. Complexing agents were added in order to avoid extraction of impurities. Extraction conditions have been studied so that extraction is almost practically complete in a single run. (Author) 19 refs

  1. MICs of Oxazolidinones for Rhodococcus equi Strains Isolated from Humans and Animals

    OpenAIRE

    Bowersock, Terry L.; Salmon, Sarah A.; Portis, Ellen S.; Prescott, John F.; Robison, Denise A.; Ford, Charles W.; Watts, Jeffrey L.

    2000-01-01

    Eperezolid and linezolid are representatives of a new class of orally active, synthetic antimicrobial agents. The in vitro activity values (MICs) of linezolid, eperezolid, and comparator antibiotics against 102 strains of Rhodococcus equi isolated from humans and animals were determined. Linezolid was more active than eperezolid against the strains tested; premafloxacin was the most active comparator antibiotic.

  2. EVIDENCE OF CLUSTERING FOR THE MIC-3 ROOT-SPECIFIC GENE FAMILY ASSOCIATED WITH NEMATODE RESISTANCE IN GOSSYPIUM SPP.

    Science.gov (United States)

    MIC-3 is a recently identified gene shown to exhibit increased root-specific expression following nematode infection of plants that are resistant to root-knot nematode (RKN). We cloned and sequenced PCR-amplicons (derived from MIC-3-specific degenerate primers) from individual plant DNAs to [1] det...

  3. Macrophage inhibitory cytokine-1 (MIC-1/GDF15 gene deletion promotes cancer growth in TRAMP prostate cancer prone mice.

    Directory of Open Access Journals (Sweden)

    Yasmin Husaini

    Full Text Available The divergent TGF-β superfamily member, macrophage inhibitory cytokine-1 (MIC-1/GDF15, is overexpressed by most cancers, including prostate cancer (PCa. Whilst its circulating levels are linked to cancer outcome, the role MIC-1/GDF15 plays in cancer development and progression is incompletely understood. To investigate its effect on PCa development and spread, we have used TRAMP prostate cancer prone mice bearing a germline deletion of MIC-1/GDF15 (TRAMPMIC-/-. On average TRAMPMIC-/- mice died about 5 weeks earlier and had larger prostatic tumors compared with TRAMP mice that were wild type for MIC-1/GDF15 (TRAMPMIC+/+. Additionally, at the time of death or ethical end point, even when adjusted for lifespan, there were no significant differences in the number of mice with metastases between the TRAMPMIC+/+ and TRAMPMIC-/- groups. However, consistent with our previous data, more than twice as many TRAMP mice overexpressing MIC-1/GDF15 (TRAMPfmsmic-1 had metastases than TRAMPMIC+/+ mice (p<0.0001. We conclude that germ line gene deletion of MIC-1/GDF15 leads to increased local tumor growth resulting in decreased survival consistent with an overall protective role for MIC-1/GDF15 in early primary tumor development. However, in advancing disease, as we have previously noted, MIC-1/GDF15 overexpression may promote local invasion and metastatic spread.

  4. The "Binarity and Magnetic Interactions in various classes of stars" (BinaMIcS) project

    Science.gov (United States)

    Neiner, C.; Morin, J.; Alecian, E.

    2015-12-01

    The "Binarity and Magnetic Interactions in various classes of stars" (BinaMIcS) project is based on two large programs of spectropolarimetric observations with ESPaDOnS at CFHT and Narval at TBL. Three samples of spectroscopic binaries with two spectra (SB2) are observed: known cool magnetic binaries, the few known hot magnetic binaries, and a survey sample of hot binaries to search for additional hot magnetic binaries. The goal of BinaMIcS is to understand the complex interplay between stellar magnetism and binarity. To this aim, we will characterise and model the magnetic fields, magnetospheric structure and coupling of both components of hot and cool close binary systems over a significant range of evolutionary stages, to confront current theories and trigger new ones. First results already provided interesting clues, e.g. about the origin of magnetism in hot stars.

  5. The "Binarity and Magnetic Interactions in various classes of Stars" (BinaMIcS) project

    CERN Document Server

    Neiner, C; Alecian, E

    2015-01-01

    The "Binarity and Magnetic Interactions in various classes of stars" (BinaMIcS) project is based on two large programs of spectropolarimetric observations with ESPaDOnS at CFHT and Narval at TBL. Three samples of spectroscopic binaries with two spectra (SB2) are observed: known cool magnetic binaries, the few known hot magnetic binaries, and a survey sample of hot binaries to search for additional hot magnetic binaries. The goal of BinaMIcS is to understand the complex interplay between stellar magnetism and binarity. To this aim, we will characterise and model the magnetic fields, magnetospheric structure and coupling of both components of hot and cool close binary systems over a significant range of evolutionary stages, to confront current theories and trigger new ones. First results already provided interesting clues, e.g. about the origin of magnetism in hot stars.

  6. Localizing Plages on BO Mic, First steps towards chromospheric Doppler imaging

    CERN Document Server

    Wolter, U

    2005-01-01

    We have obtained a densely sampled time series of CaII H&K line profiles of the ultrafast rotating K-dwarf star BO Mic. Taken at high resolution, the spectra reveal pronounced variations of the emission core profiles. We interpret these variations as signs of concentrated chromospherically active regions, in analogy to solar plages. We further interpret the variations as partly due to the rapid growth and decay of plages, while other variations appear to be caused by plages moved over the visible stellar disk by rotation. The equivalent width of the Ca K core emission changes approximately in anti-phase to the photospheric brightness, suggesting an association of the chromospheric plage regions with pronounced dark photospheric spots. We believe that further analysis of the presented spectral time series will lead to a chromospheric Doppler image of BO mic.

  7. Correlation between beta-lactamase production and MIC values against penicillin with coagulase negative staphylococci.

    Directory of Open Access Journals (Sweden)

    Narayani T

    1989-07-01

    Full Text Available Two hundred strains of coagulase negative staphylococci (CNS isolated from various clinical specimens (116 and healthy hospital personnel (84 were investigated for the production of beta-lactamases by means of three iodometric techniques and correlated with the minimum inhibitory concentration (MIC values of penicillin-G by agar dilution technique and disc diffusion technique. One hundred and fifty (75.0% of the 200 strains tested produced beta-lactamases. Seventy two per cent of the CNS were found to be beta-lactamase positive by the starch paper technique which was the most sensitive one in our study. The MIC values of penicillin against CNS ranged from less than or equal to 1.25 to greater than or equal to 2000 units. The present study indicated the higher prevalence of beta-lactamase producers with increased penicillin resistance among CNS strains isolated from healthy carriers and hospitalised patients.

  8. Life science applications and research potential of the TwinMic spectromicroscopy station at ELETTRA

    International Nuclear Information System (INIS)

    Since its opening to the users in late 2007, the TwinMic beamline at the Elettra synchrotron has been attracting the interest of a broad life science community. The recent development and implementation of a low energy x-ray fluorescence detection mode have increased the capability and the versatility of the scanning mode of the TwinMic microscope. Now using simultaneously the x-ray transmission and emission detection systems one can perform elemental, absorption and phase contrast imaging that provides complementary chemical and morphological information for the sample under investigation. The recent achievements in the performance of the instrument using combined acquisition modes for characterization of nano and micro-structured biomaterials will be illustrated with selected exemplary results

  9. Department of Energy: MICS (Mathematical Information, and Computational Sciences Division). High performance computing and communications program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This document is intended to serve two purposes. Its first purpose is that of a program status report of the considerable progress that the Department of Energy (DOE) has made since 1993, the time of the last such report (DOE/ER-0536, {open_quotes}The DOE Program in HPCC{close_quotes}), toward achieving the goals of the High Performance Computing and Communications (HPCC) Program. The second purpose is that of a summary report of the many research programs administered by the Mathematical, Information, and Computational Sciences (MICS) Division of the Office of Energy Research under the auspices of the HPCC Program and to provide, wherever relevant, easy access to pertinent information about MICS-Division activities via universal resource locators (URLs) on the World Wide Web (WWW). The information pointed to by the URL is updated frequently, and the interested reader is urged to access the WWW for the latest information.

  10. Antifungal Susceptibility Testing to Determine MIC of Amphotericine B, Fluconazole and Ketoconazole against Ocular Fungal Infection

    Directory of Open Access Journals (Sweden)

    Mitesh H. Patel, Avani M. Patel, Sachin M. Patel, Govind L Ninama, Kamlesh R. Patel, Bharti C. Lavingia

    2011-01-01

    Full Text Available Purpose: To standardize In-vitro antifungal susceptibility testing by agar dilution method to find out minimum inhibitory concentration (MIC of Amphotericine B, fluconazole and ketoconazole against ocular fungal isolates. Methods: A total of 90 isolates (25 yeast & 65 filamentous fungi were included. The drugs were added in serial double dilution in medium containing yeast nitrogen base. The MIC was determined by inhibition of visible growth on lowest concentration of drug containing media as comparing with visible growth on drug free media. Results: Out of 25 yeast isolate, all are sensitive to Amphotericine B, 8 % & 12 % are resistant to Fluconazole & ketoconazole respectively. Out of 65 Filamentous fungi, 3 %, 20 % & 28 % are resistant to Amphotericin B, Fluconazole & Ketoconazole respectively. Conclusion: The methodology used in study is user’s friendly, reliable & cost effective.

  11. Movement and Interaction in Semantic GRIDs : Dynamic Service Generation for Agents in the MIC* Deployment Environment

    OpenAIRE

    Gouaich, Abdelkader; Cerri, Stefano A.

    2004-01-01

    We present in this position paper the foundations of the MIC* model and deployment environment as they have emerged in the last years, relate them to current evolutions on semantic GRID dynamic service generation, as reflected by OGSA/I and, more recently, by WSRF, and propose an integrated view with the previously proposed STROBE model for communicating agents leading to a quite simple yet very promising architecture that may include Human agents in the loop, uninspectable as most artificial...

  12. Ethidium Bromide MIC Screening for Enhanced Efflux Pump Gene Expression or Efflux Activity in Staphylococcus aureus▿

    OpenAIRE

    Patel, Diixa; Kosmidis, Christos; Seo, Susan M.; Kaatz, Glenn W.

    2010-01-01

    Multidrug resistance efflux pumps contribute to antimicrobial and biocide resistance in Staphylococcus aureus. The detection of strains capable of efflux is time-consuming and labor-intensive using currently available techniques. A simple and inexpensive method to identify such strains is needed. Ethidium bromide is a substrate for all but one of the characterized S. aureus multidrug-resistant (MDR) efflux pumps (NorC), leading us to examine the utility of simple broth microtiter MIC determin...

  13. Correlation between beta-lactamase production and MIC values against penicillin with coagulase negative staphylococci.

    OpenAIRE

    Narayani T; Shanmugam J; Naseema K; Bhattacharya R; Shyamkrishnan K

    1989-01-01

    Two hundred strains of coagulase negative staphylococci (CNS) isolated from various clinical specimens (116) and healthy hospital personnel (84) were investigated for the production of beta-lactamases by means of three iodometric techniques and correlated with the minimum inhibitory concentration (MIC) values of penicillin-G by agar dilution technique and disc diffusion technique. One hundred and fifty (75.0%) of the 200 strains tested produced beta-lactamases. Seventy two per cent of ...

  14. EIS study of MIC in three different zones derived from ship ballast tank model system

    OpenAIRE

    Heyer, A.; Mol, J. M. C.; D'Souza, F; De Wit, J.H.W.; G. Ferrari

    2011-01-01

    Microbiologically influenced corrosion (MIC) is a well known phenomenon in aquatic environments [1]. The presence of a biofilm on metal surface often establishes new electrochemical reaction pathways, or promotes reactions which are not normally favored in the absence of microorganisms, resulting in increased corrosion rates and on the performance of the material. A approach was made by using a new developed lab scale model system containing working electrodes in different height levels to si...

  15. Ethidium Bromide MIC Screening for Enhanced Efflux Pump Gene Expression or Efflux Activity in Staphylococcus aureus▿

    Science.gov (United States)

    Patel, Diixa; Kosmidis, Christos; Seo, Susan M.; Kaatz, Glenn W.

    2010-01-01

    Multidrug resistance efflux pumps contribute to antimicrobial and biocide resistance in Staphylococcus aureus. The detection of strains capable of efflux is time-consuming and labor-intensive using currently available techniques. A simple and inexpensive method to identify such strains is needed. Ethidium bromide is a substrate for all but one of the characterized S. aureus multidrug-resistant (MDR) efflux pumps (NorC), leading us to examine the utility of simple broth microtiter MIC determinations using this compound in identifying efflux-proficient strains. Quantitative reverse transcription-PCR identified the increased expression of one or more MDR efflux pump genes in 151/309 clinical strains (49%). Ethidium bromide MIC testing was insensitive (48%) but specific (92%) in identifying strains with gene overexpression, but it was highly sensitive (95%) and specific (99%) in identifying strains capable of ethidium efflux. The increased expression of norA with or without other genes was most commonly associated with efflux, and in the majority of cases that efflux was inhibited by reserpine. Ethidium bromide MIC testing is a simple and straightforward method to identify effluxing strains and can provide accurate predictions of efflux prevalence in large strain sets in a short period of time. PMID:20855743

  16. MIC Susceptility Testing of Nosocomial Infections at PICU in Children’s Medical Center, Iran

    Directory of Open Access Journals (Sweden)

    M Rezaei

    2006-05-01

    Full Text Available Background: The aim of this study was to determine the minimal inhibitory concentration (MIC of microorganisms causing nosocomial infections in the pediatric intensive care unit (PICU of the Children's Medical Center in Tehran. Methods: All patients with nosocomial infections in the PICU were enrolled in the study. Causative microoraganisms were coagulase positive, and coagulase negative Staphylococci and Pseudomonas aeruginosa. MIC of many antibiotics was determined by microbroth dilution according to NCCLS. Findings: Within a period of 18 months, thirty patients developed nosocomial infection including 17 cases with P.aeruginosa and 9 individuals with Staph aureus infection. The remaining 4 patients were involved with coagulase negative Staphylococci. The most common sources were respiratory tract, blood stream, wound and soft tissue. Multi-antimicrobial resistance (resistance to Amikacin, Ceftazidim, Imipenem and Ciprofloxacin was common among P. aeruginosa species All strains of Staph aureus were resistant to Methicillin (MRSA. These microorganisms were also resistant to clindamycin and ciprofloxacin in 88% of cases. Conclusion: Resistance to antimicrobial agents was high in our study, therefore routine MIC examination is necessary in PICU.

  17. Determination of halogens and sulfur in high-purity polyimide by IC after digestion by MIC.

    Science.gov (United States)

    Krzyzaniak, Sindy R; Santos, Rafael F; Dalla Nora, Flavia M; Cruz, Sandra M; Flores, Erico M M; Mello, Paola A

    2016-09-01

    In this work, a method for sample preparation of high-purity polyimide was proposed for halogens and sulfur determination by ion chromatography (IC) with conductivity detection and, alternatively, by inductively coupled plasma mass spectrometry (ICP-MS). A relatively high polyimide mass (600mg) was completely digested by microwave-induced combustion (MIC) using 20bar of O2 and 50mmolL(-1) NH4OH as absorbing solution. These conditions allowed final solutions with low carbon content (<10mgL(-1)) and suitable pH for analysis by both IC and ICP-MS. The accuracy was evaluated using a certified reference material of polymer for Cl, Br and S and spike recovery experiments for all analytes. No statistical difference (t-test, 95% of confidence level) was observed between the results obtained for Cl, Br and S by IC after MIC and the certified values. In addition, spike recoveries obtained for F, Cl, Br, I and S ranged from 94% to 101%. The proposed method was suitable for polyimide decomposition for further determination of halogens and sulfur by IC and by ICP-MS (Br and I only). Taking into account the lack of methods and the difficulty of bringing this material into solution, MIC can be considered as a suitable alternative for the decomposition of polyimide for routine quality control of halogens and sulfur using IC or ICP-MS. PMID:27343595

  18. Development of Biological Coal Gasification (MicGAS Process). Topical report, July 1991--February 1993

    Energy Technology Data Exchange (ETDEWEB)

    Srivastava, K.C.

    1993-06-01

    Laboratory and bench scale reactor research carried out during the report period confirms the feasibility of biomethanation of Texas lignite (TxL) and some other low-rank coals to methane by specifically developed unique anaerobic microbial consortia. The data obtained demonstrates specificity of a particular microbial consortium to a given lignite. Development of a suitable microbial consortium is the key to the success of the process. The Mic-1 consortium was developed to tolerate higher coal loadings of 1 and 5% TxL in comparison to initial loadings of 0.01% and 0.1% TxL. Moreover, the reaction period was reduced from 60 days to 14 to 21 days. The cost of the culture medium for bioconversion was reduced by studying the effect of different growth factors on the biomethanation capability of Mic-1 consortium. Four different bench scale bioreactor configurations, namely Rotating Biological Contactor (RBC), Upflow Fluidized Bed Reactor (UFBR), Trickle Bed Reactor (TBR), and Continuously Stirred Tank Reactor (CSTR) were evaluated for scale up studies. Preliminary results indicated highest biomethanation of TxL by the Mic-1 consortium in the CSTR, and lowest in the trickle bed reactor. However, highest methane production and process efficiency were obtained in the RBC.

  19. 关于Stn∪ I=1 mi-C4的优美性%On the Gracefulness of Graph St∪n i=1 mi-C4

    Institute of Scientific and Technical Information of China (English)

    李长春; 韩兆红; 张国阳

    2007-01-01

    本文就星形树与m-C4并图的优美性进行探讨,证明了当m≥2这类图StpUm-C4是优美图.并对星形树St与n∪ i=1 mi-C4并图Stn∪ i=1 mi-C4的优美性进行探讨.证明了当max mi≥3 i=1,2…,n这类图Stn∪ i=1 mi-C4是优美图.

  20. Macrophage inhibitory cytokine-1 (MIC-1/GDF15 slows cancer development but increases metastases in TRAMP prostate cancer prone mice.

    Directory of Open Access Journals (Sweden)

    Yasmin Husaini

    Full Text Available Macrophage inhibitory cytokine-1 (MIC-1/GDF15, a divergent member of the TGF-β superfamily, is over-expressed by many common cancers including those of the prostate (PCa and its expression is linked to cancer outcome. We have evaluated the effect of MIC-1/GDF15 overexpression on PCa development and spread in the TRAMP transgenic model of spontaneous prostate cancer. TRAMP mice were crossed with MIC-1/GDF15 overexpressing mice (MIC-1(fms to produce syngeneic TRAMP(fmsmic-1 mice. Survival rate, prostate tumor size, histopathological grades and extent of distant organ metastases were compared. Metastasis of TC1-T5, an androgen independent TRAMP cell line that lacks MIC-1/GDF15 expression, was compared by injecting intravenously into MIC-1(fms and syngeneic C57BL/6 mice. Whilst TRAMP(fmsmic-1 survived on average 7.4 weeks longer, had significantly smaller genitourinary (GU tumors and lower PCa histopathological grades than TRAMP mice, more of these mice developed distant organ metastases. Additionally, a higher number of TC1-T5 lung tumor colonies were observed in MIC-1(fms mice than syngeneic WT C57BL/6 mice. Our studies strongly suggest that MIC-1/GDF15 has complex actions on tumor behavior: it limits local tumor growth but may with advancing disease, promote metastases. As MIC-1/GDF15 is induced by all cancer treatments and metastasis is the major cause of cancer treatment failure and cancer deaths, these results, if applicable to humans, may have a direct impact on patient care.

  1. MIC(0) preconditioning of 3D FEM problems on unstructured grids: Conforming and non-conforming elements

    Science.gov (United States)

    Margenov, Svetozar; Kosturski, Nikola

    2009-04-01

    In this study, the topics of grid generation and FEM applications are studied together following their natural synergy. We consider the following three tetrahedral grid generators: NETGEN, TetGen, and Gmsh. After that, the performance of the MIC(0) preconditioned conjugate gradient (PCG) solver is analyzed for both conforming and non-conforming linear FEM problems. If positive off-diagonal entries appear in the corresponding matrix, a diagonal compensation is applied to get an auxiliary M-matrix allowing a stable MIC(0) factorization. The presented numerical experiments for elliptic and parabolic problems well illustrate the similar PCG convergence rate of the MIC(0) preconditioner for both, structured and unstructured grids.

  2. What is the 'minimum inhibitory concentration' (MIC) of pexiganan acting on Escherichia coli? - A cautionary case study

    CERN Document Server

    Jepson, Alys K; Ryan, Lloyd; Ryadnov, Maxim G; Poon, Wilson C K

    2016-01-01

    We measured the minimum inhibitory concentration (MIC) of the antimicrobial peptide pexiganan acting on Escherichia coli, and report an intrinsic variability in such measurements. These results led to a detailed study of the effect of pexiganan on the growth curve of E. coli, using a plate reader and manual plating (i.e. time-kill curves). The measured growth curves, together with single-cell observations and peptide depletion assays, suggested that addition of a sub-MIC concentration of pexiganan to a population of this bacterium killed a fraction of the cells, reducing peptide activity during the process, while leaving the remaining cells unaffected. This pharmacodynamic hypothesis suggests a considerable inoculum effect, which we quantified. Our results cast doubt on the use of the MIC as 'a measure of the concentration needed for peptide action' and show how 'coarse-grained' studies at the population level give vital information for the correct planning and interpretation of MIC measurements.

  3. Development of biological coal gasification (MicGAS process). Final report, May 1, 1990--May 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    ARCTECH has developed a novel process (MicGAS) for direct, anaerobic biomethanation of coals. Biomethanation potential of coals of different ranks (Anthracite, bitumious, sub-bitumious, and lignites of different types), by various microbial consortia, was investigated. Studies on biogasification of Texas Lignite (TxL) were conducted with a proprietary microbial consortium, Mic-1, isolated from hind guts of soil eating termites (Zootermopsis and Nasutitermes sp.) and further improved at ARCTECH. Various microbial populations of the Mic-1 consortium carry out the multi-step MicGAS Process. First, the primary coal degraders, or hydrolytic microbes, degrade the coal to high molecular weight (MW) compounds. Then acedogens ferment the high MW compounds to low MW volatile fatty acids. The volatile fatty acids are converted to acetate by acetogens, and the methanogens complete the biomethanation by converting acetate and CO{sub 2} to methane.

  4. In Vitro Synergy of Caspofungin and Itraconazole against Aspergillus spp.: MIC versus Minimal Effective Concentration End Points

    OpenAIRE

    Shalit, Itamar; Shadkchan, Yona; Samra, Zmira; Osherov, Nir

    2003-01-01

    Caspofungin and itraconazole were studied alone and in combination against 31 clinical isolates of Aspergillus spp. according to NCCLS M38-P guidelines. MICs and microscopic minimal effective concentrations (MECs) were recorded, and synergy was calculated by using both end points. Synergy or synergy to additivity was found in 30 of 31 isolates by using MIC end points. With MEC end points no synergy was found and indifference was detected in 26 of 31 strains.

  5. Thread-Level Parallelization and Optimization of NWChem for the Intel MIC Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Shan, Hongzhang; Williams, Samuel; Jong, Wibe de; Oliker, Leonid

    2014-10-10

    In the multicore era it was possible to exploit the increase in on-chip parallelism by simply running multiple MPI processes per chip. Unfortunately, manycore processors' greatly increased thread- and data-level parallelism coupled with a reduced memory capacity demand an altogether different approach. In this paper we explore augmenting two NWChem modules, triples correction of the CCSD(T) and Fock matrix construction, with OpenMP in order that they might run efficiently on future manycore architectures. As the next NERSC machine will be a self-hosted Intel MIC (Xeon Phi) based supercomputer, we leverage an existing MIC testbed at NERSC to evaluate our experiments. In order to proxy the fact that future MIC machines will not have a host processor, we run all of our experiments in tt native mode. We found that while straightforward application of OpenMP to the deep loop nests associated with the tensor contractions of CCSD(T) was sufficient in attaining high performance, significant effort was required to safely and efficiently thread the TEXAS integral package when constructing the Fock matrix. Ultimately, our new MPI OpenMP hybrid implementations attain up to 65x better performance for the triples part of the CCSD(T) due in large part to the fact that the limited on-card memory limits the existing MPI implementation to a single process per card. Additionally, we obtain up to 1.6x better performance on Fock matrix constructions when compared with the best MPI implementations running multiple processes per card.

  6. Una aproximació polièdrica al concepte microeconòmic

    OpenAIRE

    Penélope Hernández; José Vila Gisbert

    2009-01-01

    Una aproximació polièdrica al concepte microeconòmicA Polyhedral Approach to the Microeconomic ConceptEste artículo propone un enfoque tridimensional de cualquier concepto en Microeconomía y analiza las implicaciones de esta multidimensionalidad en el proceso de aprendizaje-enseñanza de la microeconomía en educación universitaria. Las tres facetas del aprendizaje presentadas son la experiencial-vivencial, la gráfico-geométrica y la matemático-formal. En cada una de ellas el lenguaje utilizado...

  7. Determination Of Appropriate Antibiotic In Bacterial Meningitis Of Children Based On MIC

    OpenAIRE

    Noorbakhsh S; SA Siadati; Rimaz S; Mamishi S.; Haghi Ashtiani T

    2005-01-01

    Background: Bacterial meningitis is one of the most serious infections in infants and children. Three organisms include S.Pneumo;N.mening;H.Influ are the most common cause of meningitis in children between 2M-14y age.Etest is a new method for determination the MIC of some antimicrobial drugs in agarose .This method is useful for some organisms like as S .Pneumo; N.mening; H.Influ;sensitive Streptococcus and anaerobic ;aerobic gram negative. Materials and Methods: In this descriptive cross sec...

  8. Gestión y TPV mostrador de tienda de cómics Riutori

    OpenAIRE

    Navarro Rivas, Isabel; Serrano Morcillo, Roberto

    2015-01-01

    Riutori es una tienda de cómics y merchandising que abrió sus puertas por primera vez en diciembre de 2005. Después de todo este tiempo llevando su gestión con diversas herramientas y queriendo evolucionar hacia el eCommerce, constató la necesidad de centralización de sus datos y en la mejora general de la gestión del comercio queriendo crear un ERP que se ajustara a su modelo de negocio que dista un poco de los que gestionan los software actuales del mercado. Los requisitos principales qu...

  9. THE CHIRONOMIDAE ASSEMBLAGES IN SOMESUL MIC RIVER (ROMANIA) DURING 1996 AND 1997

    OpenAIRE

    Maria-Monica Tudorancea; C. Tudorancea

    2001-01-01

    The communities of Chironomidae larvae in the Gilau – Gherla sector of the Somesul Mic River (Transylvania, Romania) were studied during 1996 and 1997 in order to compare their species composition and to see if their component species could be good indicators for water quality deterioration. A total of 102 species were recorded, out of which 12 are new records for the Romanian fauna. Four of these species are known only from East Asia and from the North America. Some species such as Chironomu...

  10. Mic Check: How the 99% Pitched a Movement from Occupy Wall Street to Occupy Cal

    OpenAIRE

    Bintliff, Jacob

    2012-01-01

    The University of California, Berkeley, became a site of the Occupy Movement in fall 2011. On November 9, the university found itself in the company of financial hubs, civic centers, and parks and plazas the world over when Sproul Plaza was re-appropriated by the sleeping bags and “mic checks” that came to symbolize the disenfranchised majority, "the 99%." Occupy Cal was immediately subject to a brutal suppression of student protest by the police, as both students and the university administr...

  11. Initial steps in the microbially influenced corrosion (MIC) of metallic surfaces in a natural marine environment

    International Nuclear Information System (INIS)

    Immersion of various metal samples in polluted seawater from Tenerife Harbor was followed by microbial attachment as an intermediate step in fouling development. The purpose of this research was to determine the initial steps in MIC by identifying the different microbial species attached to the respective metal or alloy. Image analysis was used to determine the morphologic changes in the metal surfaces. The corrosion products were determined by X-ray diffraction. The open circuit potentials were measured periodically and their variation with time used to assess the electrochemical behavior in the aforementioned marine environment

  12. Música y cómic. Relaciones didácticas y artísticas

    OpenAIRE

    Ortiz Hernández, Francisco Javier; Vidal Martín-Toledano, Jesús

    2014-01-01

    La didáctica de la música es una disciplina más que los alumnos de magisterio tienen implementado en el currículum de la carrera. A veces, no solo basta con que los alumnos alcancen a interpretar un conjunto de canciones, sino que deben conocer previamente la historia del desarrollo de la música a lo largo de la historia del hombre. De esta manera, se puede alcanzar a comprender el desarrollo de la misma, y a poder explicarlo mejor a los futuros alumnos. El cómic, que mezcla elementos que tam...

  13. MIC damage in a water coolant header for remote process equipment

    International Nuclear Information System (INIS)

    Stainless steel water piping used to supply coolant for remote chemical separations equipment developed leaks during low flow conditions resulting from an extended interruption of operations. All the leaks occurred at welds in the bottom zone of the pipe, which was blanketed with silt deposits from the unfiltered well water used for cooling. Ultrasonic, radiographic, and metallographic examinations of leak sites revealed worm hole pitting adjacent to the welds. Seepage at the penetrations was strongly acidic and resulted in corrosion on the external pipe surfaces beneath brown crusty deposits which had developed. Analyses of the water and deposits suggest a strong propensity toward microbiologically influenced corrosion (MIC) and fouling

  14. Fotonovela: transmedia entre el cómic y el vídeo arte

    OpenAIRE

    Montalvo, Blanca; Martínez Silvente, Mª Jesús; Miranda Mas, Carlos

    2016-01-01

    Esta ponencia se propone analizar el lenguaje de la fotonovela como un formato transmedia entre el cómic, el cine y el vídeo arte. También apostamos por una recuperación del formato, en la era de la imagen digital. Para llevarlo a cabo, analizamos las propuestas más experimentales desarrolladas a finales del siglo pasado, desde las fotonovelas punk de Robert Crumpo al terror de Doomlord, comparamos estas prácticas con obras de cine y arte que tambien desarrollan la narración temporal mediante...

  15. Supervisió i control de reactors químics

    OpenAIRE

    Colomer Llamas, David

    2015-01-01

    En el present projecte es pot veure des de zero l’automatització d’un procés de producció que consta de 4 reactors químics CSTR disposats en sèrie. La simulació de les respostes del procés es porta a terme amb el software Matlab SIMULINK, el control es realitza amb el software RSLogix 5000 de Rockwell i el sistema SCADA amb el software System Platform 2014 R2 de Wonderware. Finalment s’integren les 3 parts mitjançant comunicació OPC i es comprova tot el funcionament com si e...

  16. Optimizing the Betts-Miller-Janjic cumulus parameterization with Intel Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.-L.

    2015-10-01

    The schemes of cumulus parameterization are responsible for the sub-grid-scale effects of convective and/or shallow clouds, and intended to represent vertical fluxes due to unresolved updrafts and downdrafts and compensating motion outside the clouds. Some schemes additionally provide cloud and precipitation field tendencies in the convective column, and momentum tendencies due to convective transport of momentum. The schemes all provide the convective component of surface rainfall. Betts-Miller-Janjic (BMJ) is one scheme to fulfill such purposes in the weather research and forecast (WRF) model. National Centers for Environmental Prediction (NCEP) has tried to optimize the BMJ scheme for operational application. As there are no interactions among horizontal grid points, this scheme is very suitable for parallel computation. With the advantage of Intel Xeon Phi Many Integrated Core (MIC) architecture, efficient parallelization and vectorization essentials, it allows us to optimize the BMJ scheme. If compared to the original code respectively running on one CPU socket (eight cores) and on one CPU core with Intel Xeon E5-2670, the MIC-based optimization of this scheme running on Xeon Phi coprocessor 7120P improves the performance by 2.4x and 17.0x, respectively.

  17. The coronal structure of Speedy Mic - I: A densely packed prominence system beyond co-rotation

    CERN Document Server

    Dunstone, N J; Cameron, A C; Jardine, M

    2006-01-01

    We present new observations of the prominence system on the K3 dwarf Speedy Mic (BO Mic, HD 197890). Using an improved technique to track the absorption features in H_alpha we find a very active prominence system with approximately ten prominences on the observable hemisphere per rotation. From a total of 25 prominences we find an average axial distance of 2.85+/-0.54 R_* which is twice the co-rotation radius above the stellar surface. We discuss the consequences of these observations on the nature of the supporting magnetic structures. Two consecutive nights, with complete phase coverage, combined with a further night after a three night gap allow us to study the evolution of the prominence system on two different timescales. Several of the prominences have counterparts at similar phases on consecutive nights. During this interval many prominences show evidence for evolution in their heights and phases of observation. Five nights (13 rotation cycles) later we recover many prominences at approximately the sam...

  18. Non-destructive on-line monitoring of MIC (microbially influenced corrosion)

    Energy Technology Data Exchange (ETDEWEB)

    White, D.C. (Oak Ridge National Lab., TN (USA) Tennessee Univ., Knoxville, TN (USA)); Nivens, D.E.; Mittelman, M.W. (Tennessee Univ., Knoxville, TN (USA). Inst. for Applied Microbiology); Chambers, J.Q. (Tennessee Univ., Knoxville, TN (USA). Dept. of Chemistry); King, J.M.H. (Tennessee Univ., Knoxville, TN (USA). Center for Environmental Biotechnology); Sayler, G.S. (Tennessee Univ., Knoxville, TN

    1990-01-01

    The formation of microbial biofilms on metal surfaces with the subsequent increase in heat transfer resistance and the induction of microbially influenced corrosion (MIC) is being increasingly recognized as an extremely important economic and safety problem for industrial water systems. The development of sufficiently rugged and accurate monitoring devices by which biofilm formation and activity of microbial biofilms can be monitored non-destructively, directly in water systems is the goal of this research. This on-line systems would allow the effective utilization of minimal levels of biocides and inhibitors as well as permit in situ testing of materials for MIC resistance. Several non-destructive technologies such as the quartz crystal microbalance (QCM), the attenuated total reflectance-Fourier transforming infrared spectrometer (ATR-FT/IR), and a genetically engineered bacterium containing the lux gene cassette in which its bioluminescence can be used to define its presence on coupons are on-line devices which accurately measure biofilm formation. Corrosion activity can be estimated by electrochemical impedance. 12 refs., 8 figs.

  19. Memory characteristics of poly-Si using MIC as an active layer on glass substrates

    International Nuclear Information System (INIS)

    In this paper the electrical properties of nonvolatile memory (NVM) using multi-stack gate insulators of oxide-nitride-oxynitride (ONOn) and an active layer of low temperature polycrystalline silicon (LTPS) were investigated. From hydrogenated amorphous silicon (a-Si : H), the LTPS thin film with a high crystalline fraction of 96% and a low surface roughness of 1.28 nm was fabricated by metal induced crystallization (MIC) with annealing conditions of 650 0C for 5 h on glass substrates. The LTPS thin film transistor or the NVM had a field effect mobility of (μFE) 10 cm2 V-1 s-1 and a threshold voltage (VTH) of -3.5 V. The results demonstrated that the NVM had a memory window of 1.6 V with a programming and erasing (P/E) voltage of -14 V and 14 V in 1 ms. Moreover, retention properties of the memory were shown to exceed 80% after 10 years. Therefore, the LTPS fabricated by MIC has become a potential material for NVM application which is employed for the system integration of panel displays.

  20. Memory characteristics of poly-Si using MIC as an active layer on glass substrates

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Thanh Nga; Jung, Sungwook; Nguyen, Van Duy; Yi, Junsin, E-mail: yi@yurim.skku.ac.k [School of Information and Communication Engineering, Sungkyunkwan University, Suwon, Kyouggi 440-746 (Korea, Republic of)

    2010-03-17

    In this paper the electrical properties of nonvolatile memory (NVM) using multi-stack gate insulators of oxide-nitride-oxynitride (ONOn) and an active layer of low temperature polycrystalline silicon (LTPS) were investigated. From hydrogenated amorphous silicon (a-Si : H), the LTPS thin film with a high crystalline fraction of 96% and a low surface roughness of 1.28 nm was fabricated by metal induced crystallization (MIC) with annealing conditions of 650 {sup 0}C for 5 h on glass substrates. The LTPS thin film transistor or the NVM had a field effect mobility of ({mu}{sub FE}) 10 cm{sup 2} V{sup -1} s{sup -1} and a threshold voltage (V{sub TH}) of -3.5 V. The results demonstrated that the NVM had a memory window of 1.6 V with a programming and erasing (P/E) voltage of -14 V and 14 V in 1 ms. Moreover, retention properties of the memory were shown to exceed 80% after 10 years. Therefore, the LTPS fabricated by MIC has become a potential material for NVM application which is employed for the system integration of panel displays.

  1. Application of Intel Many Integrated Core (MIC) accelerators to the Pleim-Xiu land surface scheme

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.

    2015-10-01

    The land-surface model (LSM) is one physics process in the weather research and forecast (WRF) model. The LSM includes atmospheric information from the surface layer scheme, radiative forcing from the radiation scheme, and precipitation forcing from the microphysics and convective schemes, together with internal information on the land's state variables and land-surface properties. The LSM is to provide heat and moisture fluxes over land points and sea-ice points. The Pleim-Xiu (PX) scheme is one LSM. The PX LSM features three pathways for moisture fluxes: evapotranspiration, soil evaporation, and evaporation from wet canopies. To accelerate the computation process of this scheme, we employ Intel Xeon Phi Many Integrated Core (MIC) Architecture as it is a multiprocessor computer structure with merits of efficient parallelization and vectorization essentials. Our results show that the MIC-based optimization of this scheme running on Xeon Phi coprocessor 7120P improves the performance by 2.3x and 11.7x as compared to the original code respectively running on one CPU socket (eight cores) and on one CPU core with Intel Xeon E5-2670.

  2. Study of a new type anode of OLED by MIC poly-Si

    Science.gov (United States)

    Li, Yang; Meng, Zhiguo; Wu, Chunya; Man, Wong; Hoi, Kwok Sing; Xiong, Shaozhen

    2007-11-01

    In this paper, a boron-doped poly-Si crystallized by solution-based metal induced (S-MIC) as the anode of organic light emitting diode (OLED) was studied. The semi-transparent and semi-reflective anode of OLED systemized with the high reflectivity of Al cathode could form a micro-cavity structure with a low Q to improve the efficiency. The maximum luminance efficiency of red OLED made by Alq3: DCJTB (1.5wt %)( 30nm) with the poly-Si anode is 2.66cd/A, higher than that of the OLED with the ITO anodes by 30%. In order to improve the device performance, some key to optimize the character of MIC poly-Si thin film are analyzed theoretically. A new kind of TFT/OLED coupling structure in AMOLED was proposed, in which the pixel electrode of OLED was made by the same poly-Si thin film with its driver TFT's drain electrode. So that this coupling structure will simplify the AMOLED processes flow.

  3. High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus

    Science.gov (United States)

    Viedma, Esther; Chaves, Fernando; Lalueza, Antonio; Fortún, Jesús; Loza, Elena; Pujol, Miquel; Ardanuy, Carmen; Morales, Isabel; de Cueto, Marina; Resino-Foz, Elena; Morales-Cartagena, Alejandra; Rico, Alicia; Romero, María P.; Orellana, María Ángeles; López-Medrano, Francisco; Fernández-Ruiz, Mario; Aguado, José María

    2016-01-01

    We investigated the prognostic role of high MICs for antistaphylococcal agents in patients with methicillin-sensitive Staphylococcus aureus catheter-related bloodstream infection (MSSA CRBSI). We prospectively reviewed 83 episodes from 5 centers in Spain during April 2011–June 2014 that had optimized clinical management and analyzed the relationship between E-test MICs for vancomycin, daptomycin, oxacillin, and linezolid and development of complicated bacteremia by using multivariate analysis. Complicated MSSA CRBSI occurred in 26 (31.3%) patients; MICs for vancomycin and daptomycin were higher in these patients (optimal cutoff values for predictive accuracy = 1.5 μg/mL and 0.5 μg/mL). High MICs for vancomycin (hazard ratio 2.4, 95% CI 1.2–5.5) and daptomycin (hazard ratio 2.4, 95% CI 1.1–5.9) were independent risk factors for development of complicated MSSA CRBSI. Our data suggest that patients with MSSA CRBSI caused by strains that have high MICs for vancomycin or daptomycin are at increased risk for complications. PMID:27192097

  4. High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus.

    Science.gov (United States)

    San-Juan, Rafael; Viedma, Esther; Chaves, Fernando; Lalueza, Antonio; Fortún, Jesús; Loza, Elena; Pujol, Miquel; Ardanuy, Carmen; Morales, Isabel; de Cueto, Marina; Resino-Foz, Elena; Morales-Cartagena, Alejandra; Rico, Alicia; Romero, María P; Orellana, María Ángeles; López-Medrano, Francisco; Fernández-Ruiz, Mario; Aguado, José María

    2016-06-01

    We investigated the prognostic role of high MICs for antistaphylococcal agents in patients with methicillin-sensitive Staphylococcus aureus catheter-related bloodstream infection (MSSA CRBSI). We prospectively reviewed 83 episodes from 5 centers in Spain during April 2011-June 2014 that had optimized clinical management and analyzed the relationship between E-test MICs for vancomycin, daptomycin, oxacillin, and linezolid and development of complicated bacteremia by using multivariate analysis. Complicated MSSA CRBSI occurred in 26 (31.3%) patients; MICs for vancomycin and daptomycin were higher in these patients (optimal cutoff values for predictive accuracy = 1.5 μg/mL and 0.5 μg/mL). High MICs for vancomycin (hazard ratio 2.4, 95% CI 1.2-5.5) and daptomycin (hazard ratio 2.4, 95% CI 1.1-5.9) were independent risk factors for development of complicated MSSA CRBSI. Our data suggest that patients with MSSA CRBSI caused by strains that have high MICs for vancomycin or daptomycin are at increased risk for complications. PMID:27192097

  5. THE CHIRONOMIDAE ASSEMBLAGES IN SOMESUL MIC RIVER (ROMANIA DURING 1996 AND 1997

    Directory of Open Access Journals (Sweden)

    Maria-Monica Tudorancea

    2001-01-01

    Full Text Available The communities of Chironomidae larvae in the Gilau – Gherla sector of the Somesul Mic River (Transylvania, Romania were studied during 1996 and 1997 in order to compare their species composition and to see if their component species could be good indicators for water quality deterioration. A total of 102 species were recorded, out of which 12 are new records for the Romanian fauna. Four of these species are known only from East Asia and from the North America. Some species such as Chironomus thumi, Microcricotopus bicolor, Dicrotendipes nervosus and Dicrotendipes notatus occurred in organically enriched waters. Other species, such as Cricotopus algarum, Cricotopus bicinctus, Cricotopus tremulus and Cricotopus trifasciatus occurred in both clean and organically polluted water which indicate they are not good bioindicators for water quality deterioration.

  6. ABUNDANCE AND SEASONAL DYNAMICS OF MAYFLY COMMUNITIES (INSECTA: EPHEMEROPTERA FROM SOMESUL MIC RIVER (ROMANIA

    Directory of Open Access Journals (Sweden)

    Milca Petrovici

    2001-01-01

    Full Text Available The collecting of quantitative benthos samples in 1996-1997, at three sampling sites on the Someşul Mic River, allowed the identification of 12 species of 5 families. The highest diversity was found upstream Cluj-Napoca, and it had decreased downstream town, the mayfly being absent downstream Gherla. Baëtis lutheri along with Baëtis vernus, were the dominant species upstream the town. Baëtis vernus was the only species present downstream Cluj Napoca, in every season. The presence of that species, with very low densities, and being the only identified species in some seasons, reflect a high depreciation of the water quality by the city of Cluj-Napoca. This species although known as very pollution tolerant, absent in the benthos of the river after crossing Gherla industrial town.

  7. El turisme gastronòmic : autenticitat i desenvolupament local en zones rurals

    OpenAIRE

    Fusté Forné, Francesc

    2015-01-01

    Un dels turismes especialitzats que està assolint major importància en l’actualitat és el turisme gastronòmic. L’activitat agrícola i ramadera tradicional en l’àmbit del turisme rural està veient com la pràctica turística li guanya terreny, i en aquest sentit la gastronomia representa la integració dels trets característics del paisatge, tant natural com cultural, d’una destinació. No obstant, l’autenticitat pròpia de cada territori ha de fer front a una globalització cada vegada més ferotge,...

  8. El Moviment Olímpic i el món acadèmic

    OpenAIRE

    Puig Brandes, Núria

    2011-01-01

    Núria Puig, responsable de Relacions amb les Universitats del CIO, aborda al seu article “El Moviment Olímpic i el món acadèmic” l’important paper que des de la Grècia antiga, però també als orígens del Moviment Olímpic modern, ha tingut el món acadèmic, i més endavant se centra en el paper dels centres d’estudis olímpics a diferents universitats del món i del Centre d’Estudis Olímpics del CIO amb els seus diferents serveis. Núria Puig, responsable de relaciones con las universidades del C...

  9. Evolution of the ring current ion population, as observed by the CRRES/MICS instrument

    International Nuclear Information System (INIS)

    Using the MICS instrument on CRRES, we have examined high charge state magnetospheric ions in the energy range 20 endash 400 keV/Q, believed to be originally solar wind material, as well as singly charged Oxygen and helium. We will present survey plots of MICS data from the whole CRRES mission. These show a number of interesting features. In particular, it can be seen that the generic feature of storm bulk ring current composition changes is the emergence of a concentration of ionospheric material at low (L=3) altitude, and its rise to higher L-shells during the recovery. By contrast, solar wind material remains preponderantly at higher L-shells, and a belt of ring current alphas forms around L=4. The altitude of the peak in ionospheric material is a strong function of Dst. Substorms are seen to reflect the background composition at energization, with onset properties apparently unrelated to injection composition, but may contribute to the upflow of oxygen subsequent to onset. During the solar storm of March 1991 we see a considerable increase in the numbers of alpha particles, Fe, Si and other species. Simultaneous changes in their charge states are seen. For example, in the case of iron, we can recognize charge peaks around 9 and 16, and swings between the dominant charge state. The swings in other species charge states are consistent with a change in source temperature from 1.1 to 2.5 million degrees, as expected for different streams of coronal origin. It is clear that this material is locally trapped within the magnetosphere, which suggests that not only has there been an abrupt change between fast and slow stream material, but also that this signature has penetrated promptly to geostationary altitude. This hypothesis is to some extent confirmed by data from the GOES 7 satellite, which shows evidence of a sudden compression of the magnetosphere coincident with the start of the main period of high charge state material

  10. Comparison of the MIC 2000 enteric media with API 20 E and conventional methods for identification of Enterobacteriaceae.

    Science.gov (United States)

    Courcol, R J; Husson, M O; Izard, D E; Martin, G R

    1982-09-01

    By using MIC 2000 Enteric Identification Media the identification of Enterobacteriaceae was evaluated. 421 strains of Enterobacteriaceae belonging to 23 taxa were identified by MIC 2000, and the conventional method API 20 E, respectively. The results obtained are almost identical, i.e. 96.2% and 96.7%. Besides, the results showed no statistical difference between the two miniaturized systems (p greater than 0.1). The MIC 2000 Enteric Media are capable of identifying the majority of Enterobacteriaceae with a reasonable degree of reliability. This system appears to be efficient and flexible. It is convenient to determine the minimal inhibitory concentration of the tested strain on the same microplate. PMID:6758421

  11. The lessons of Bhopal [toxic] MIC gas disaster scope for expanding global biomonitoring and environmental specimen banking.

    Science.gov (United States)

    Sriramachari, S; Chandra, H

    1997-05-01

    Bhopal Toxic gas tragedy represents one of the worst chemical accidents of the world. Autopsy and toxicological studies, apart from presenting evidence of acute and even chronic cyanide toxicity, provided a unique example of the incriminated chemical being traced to the bodies of the victims. The entry of methyl isocyanate (MIC) into the blood stream was established by the presence of carbamoylated end-terminal amino acids of haemoglobin and other tissue proteins. The presence of MIC trimer and a few other identified as well as unidentified tank residue constituents in the blood and viscera further established a close nexus of the products of pyrolysis of MIC in the aerosol inhaled by the victims. The Bhopal studies exemplify the scope for biological monitoring (BM) and environmental specimen banking (ESB) in chemical accidents as part of the global efforts. PMID:9159916

  12. MIC program for calculational simulation of experiments on measuring the control rod efficiency by the method of interference corrections

    International Nuclear Information System (INIS)

    The MIC program aimed for methematical simulation of experiments on measuring reactor control system absorbing rod efficiency and obtained data processing is described. The method of interference corrections used for calculations permits on the base of known values of single control rod efficiency and their mutual influence to determine the efficiency of the system in a whole. The values of the interference corrections for the MIC program are calculated by means of the PNK heterogeneous program. The program is written in FORTRAN for the BESM-6 computers

  13. Postantibiotic Effect and Postantibiotic Sub-MIC Effect of Levofloxacin Compared to Those of Ofloxacin, Ciprofloxacin, Erythromycin, Azithromycin, and Clarithromycin against 20 Pneumococci

    OpenAIRE

    Spangler, Sheila K.; Lin, Gengrong; Jacobs, Michael R.; Appelbaum, Peter C.

    1998-01-01

    The postantibiotic effect (PAE) (10 times the MIC of quinolones, 5 times the MIC of macrolides) and postantibiotic sub-MIC effect (PAE-SME) at 0.125, 0.25, and 0.5 times the MIC were determined for levofloxacin, ciprofloxacin, ofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. Quinolone PAEs ranged between 0.5 and 6.5 h, and macrolide PAEs ranged between 1 and 6 h. Measurable PAE-SMEs (in hours) at the three concentrations were 1 to 5, 1 to 8, and 1 to 8, respec...

  14. Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci.

    Science.gov (United States)

    Spangler, S K; Lin, G; Jacobs, M R; Appelbaum, P C

    1998-05-01

    The postantibiotic effect (PAE) (10 times the MIC of quinolones, 5 times the MIC of macrolides) and postantibiotic sub-MIC effect (PAE-SME) at 0.125, 0.25, and 0.5 times the MIC were determined for levofloxacin, ciprofloxacin, ofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. Quinolone PAEs ranged between 0.5 and 6.5 h, and macrolide PAEs ranged between 1 and 6 h. Measurable PAE-SMEs (in hours) at the three concentrations were 1 to 5, 1 to 8, and 1 to 8, respectively, for quinolones and 1 to 8, 1 to 8, and 1 to 6, respectively, for macrolides. PMID:9593160

  15. Microbially influenced corrosion (MIC) analyses of the BNGS-B vacuum building. Report No. 92-185-K. [BNGS (Bruce Nuclear Generating Station)

    Energy Technology Data Exchange (ETDEWEB)

    Jain, D.K.

    1992-01-01

    Microbially influenced corrosion (MIC) has been found to play a significant role in causing corrosion, especially in those industries which use natural waters. The most significant of the organisms found to cause corrosion are the sulphate-reducing bacteria (SRB), particularly with anoxic deposits or stagnant weirs. In May 1992, the Bruce Nuclear Generating Station B Vacuum Building was inspected for MIC after being in service for 10 years. This report provides results for both on-site MIC inspection and for microbiological analysis of sediments, water, and slime deposits for evidence of MIC bacteria.

  16. Antimicrobial Activity of Serbian Propolis Evaluated by Means of MIC, HPTLC, Bioautography and Chemometrics.

    Science.gov (United States)

    Ristivojević, Petar; Dimkić, Ivica; Trifković, Jelena; Berić, Tanja; Vovk, Irena; Milojković-Opsenica, Dušanka; Stanković, Slaviša

    2016-01-01

    New information has come to light about the biological activity of propolis and the quality of natural products which requires a rapid and reliable assessment method such as High Performance Thin-Layer Chromatography (HPTLC) fingerprinting. This study investigates chromatographic and chemometric approaches for determining the antimicrobial activity of propolis of Serbian origin against various bacterial species. A linear multivariate calibration technique, using Partial Least Squares, was used to extract the relevant information from the chromatographic fingerprints, i.e. to indicate peaks which represent phenolic compounds that are potentially responsible for the antimicrobial capacity of the samples. In addition, direct bioautography was performed to localize the antibacterial activity on chromatograms. The biological activity of the propolis samples against various bacterial species was determined by a minimum inhibitory concentration assay, confirming their affiliation with the European poplar type of propolis and revealing the existence of two types (blue and orange) according to botanical origin. The strongest antibacterial activity was exhibited by sample 26 against Staphylococcus aureus, with a MIC value of 0.5 mg/mL, and Listeria monocytogenes, with a MIC as low as 0.1 mg/mL, which was also the lowest effective concentration observed in our study. Generally, the orange type of propolis shows higher antimicrobial activity compared to the blue type. PLS modelling was performed on the HPTLC data set and the resulting models might qualitatively indicate compounds that play an important role in the activity exhibited by the propolis samples. The most relevant peaks influencing the antimicrobial activity of propolis against all bacterial strains were phenolic compounds at RF values of 0.37, 0.40, 0.45, 0.51, 0.60 and 0.70. The knowledge gained through this study could be important for attributing the antimicrobial activity of propolis to specific chemical

  17. Evolution of the ring current ion population, as observed by the CRRES/MICS instrument

    International Nuclear Information System (INIS)

    Using the MICS instrument on CRRES, we have examined high charge state magnetospheric ions in the energy range 20-400 keV/Q, believed to be originally solar wind material, as well as singly charged Oxygen and helium. We will present survey plots of MICS data from the whole CRRES mission. These show a number of interesting features. In particular, it can be seen that the generic feature of storm bulk ring current composition changes is the emergence of a concentration of ionospheric material at low (L=3) altitude, and its rise to higher L-shells during the recovery. By contrast, solar wind material remains preponderantly at higher L-shells, and a belt of ring current alphas forms around L=4. The altitude of the peak in ionospheric material is a strong function of Dst. Substorms are seen to reflect the background composition at energization, with onset properties apparently unrelated to injection composition, but may contribute to the upflow of oxygen subsequent to onset. During the solar storm of March 1991 we see a considerable increase in the numbers of alpha particles, Fe, Si and other species. Simultaneous changes in their charge states are seen. For example, in the case of iron, we can recognize charge peaks around 9 and 16, and swings between the dominant charge state. The swings in other species charge states are consistent with a change in source temperature from 1.1 to 2.5 million degrees, as expected for different streams of coronal origin. It is clear that this material is locally trapped within the magnetosphere, which suggests that not only has there been an abrupt change between fast and slow stream material, but also that this signature has penetrated promptly to geostationary altitude. This hypothesis is to some extent confirmed by data from the GOES 7 satellite, which shows evidence of a sudden compression of the magnetosphere coincident with the start of the main period of high charge state material. The signature of a change from low to high

  18. Minimal inhibitory concentration (MIC determination of disinfectant and/or sterilizing agents

    Directory of Open Access Journals (Sweden)

    Priscila Gava Mazzola

    2009-06-01

    Full Text Available Due to the growing number of outbreaks of infection in hospital and nurseries, it becomes essential to set up a sanitation program that indicates that the appropriate chemical agent was chosen for application in the most effective way. Validating the effectiveness of decontamination and disinfection is an important and often challenging task. In order to study and compare the behavior of selected microorganisms, they were submitted to minimal inhibitory concentration (MIC. The MIC intervals, which reduced bacteria populations over 6 log10, were: 59 to 156 mg/L of quaternary ammonium compounds (QACs; 63 to 10000 mg/L of chlorhexidine; 1375 to 3250 mg/L of glutaraldehyde; 39 to 246 mg/L of formaldehyde; 43750 to 87500 mg/L of ethanol; 1250 to 6250 mg/L of iodine in polyvinyl-pyrolidone complexes, 150 to 4491 mg/L of chlorine-releasing-agents (CRAs and 469 to 2500 mg/L of hydrogen peroxide. Chlorhexidine showed non inhibitory activity over germinating spores. A. calcoaceticus showed resistance to the majority of the agents tested, followed by E. cloacae and S. marcescens.Devido ao número crescente de surtos de infecção hospitalar, torna-se proeminente o estabelecimento de um programa de sanitização que liste os agentes químicos a serem empregados e o modo de aplicação mais efetivo. Validação da eficácia de descontaminação é uma tarefa ao mesmo tempo importante e desafiadora. Para estudar e comparar o comportamento dos microrganismos selecionados foram realizados ensaios de concentração inibitória mínima (CIM. A CIM capaz de reduzir o bioburden inicial (>6 log10 foi: 59 - 156 mg/L de quartenários de amônia; 63 - 10000 mg/L de clorexidina, 1375 - 3250 mg/mL de glutaraldeído, 39 - 246 mg/L de formaldeído, 43750 - 87500 mg/L de etanol 1250 - 6250 mg/L de PVPI, 150 - 4491 mg/L de compostos liberadores de cloro e 469 -2500 mg/L de peróxido de hidrogênio.

  19. Introducció a l'ús del simulador de processos químics CHEMCAD 5.2.0

    OpenAIRE

    Gómez Siurana, Amparo; Font Escamilla, Alicia; Menargues Irles, Sergio

    2007-01-01

    Es tracta d'un manual on s'explica, mitjançant l'ajuda d'exemples resolts, l'ús del simulador comercial de processos químics Chemcad 5.2.0. Secretariat de Promoció del Valencià, Universitat d'Alacant; Conselleria de Cultura, Educació i Ciència; CAM

  20. β-Aescin at subinhibitory concentration (sub-MIC) enhances susceptibility of Candida glabrata clinical isolates to nystatin.

    Science.gov (United States)

    Franiczek, Roman; Gleńsk, Michał; Krzyżanowska, Barbara; Włodarczyk, Maciej

    2015-11-01

    Aescin (escin) derived from the seeds of horse chestnut (Aesculus hippocastanum L.) is a natural mixture of triterpene saponins exhibiting a wide variety of pharmacological properties, including antiinflammatory, analgesic, and antipyretic activities. However, data concerning antifungal activities of these compounds are limited. This study aims to evaluate the in vitro antifungal susceptibility of Candida glabrata clinical isolates to α-aescin sodium, β-aescin crystalline and β-aescin sodium using the disk diffusion (DD) and broth microdilution (BMD) methods. Moreover, the influence of subinhibitory concentration (0.5×MIC) of β-aescins on the nystatin MIC was also studied. In general, the results obtained by the DD assay correlated well with those obtained by the BMD method. Both β-aescins effectively inhibited the growth of all 24 strains tested. The minimum inhibitory concentration (MIC) values ranging from 8 to 32 μg/ml for β-aescin crystalline, whereas those of β-aescin sodium were slightly lower and ranged from 4 to 16 μg/ml. In contrast, α-aescin sodium was found to be completely ineffective against the strains studied. MIC values of nystatin were reduced 2-16-fold and 2-4-fold in the presence of subinhibitory concentration of β-aescin crystalline and β-aescin sodium, respectively. Results of the present study may suggest the additive interaction between β-aescin and nystatin. PMID:26092104

  1. Synthesis of 1-Substituted Isoquinolines by Heterocyclization of TosMIC Derivatives: Total Synthesis of Cassiarin A.

    Science.gov (United States)

    Gutiérrez, Sara; Coppola, Anna; Sucunza, David; Burgos, Carolina; Vaquero, Juan J

    2016-07-15

    A new method for the synthesis of 1-substituted isoquinolines by a heterocyclization that involves α-benzyl TosMIC derivatives and different electrophiles has been developed. This methodology has been successfully applied to a total synthesis of cassiarin A, an alkaloid with potent antiplasmodial activity against Plasmodium falciparum. PMID:27351205

  2. The coronal structure of Speedy Mic - II: Prominence masses and off-disc emission

    CERN Document Server

    Dunstone, N J; Barnes, J R; Jardine, M

    2006-01-01

    Observations of stellar prominences on young rapidly rotating stars provide unique probes of their magnetic fields out to many stellar radii. We compare two independently obtained datasets of the K3 dwarf Speedy Mic using the Anglo-Australian Telescope (AAT) and the ESO Very Large Telescope (VLT). Taken more than a fortnight apart they provide the first insight into the evolution of the prominence system on such a young rapidly rotating star. The largest prominences observed transiting the stellar disc are found at very similar rotational phases between the epochs. This suggests that the magnetic structures supporting the prominences retain their identity on a two to three week timescale. We identify prominences as transient absorption features in all lines of the Hydrogen Balmer series down to H_10. We use the ratios of the prominence EWs in these lines to determine their column densities in the first excited state of hydrogen. We determine the optical depths, finding prominences to be rather optically thick...

  3. The AU Mic Debris Disk: far-infrared and submillimeter resolved imaging

    CERN Document Server

    Matthews, Brenda C; Sibthorpe, Bruce; Holland, Wayne; Booth, Mark; Kalas, Paul; MacGregor, Meredith; Wilner, David; Vandenbussche, Bart; Olofsson, Göran; Blommaert, Joris; Brandeker, Alexis; Dent, W R F; de Vries, Bernard L; Di Francesco, James; Fridlund, Malcolm; Graham, James R; Greaves, Jane; Heras, Ana M; Hogerheijde, Michiel; Ivison, R J; Pantin, Eric; Pilbratt, Göran L

    2015-01-01

    We present far-infrared and submillimeter maps from the Herschel Space Observatory and the James Clerk Maxwell Telescope of the debris disk host star AU Microscopii. Disk emission is detected at 70, 160, 250, 350, 450, 500 and 850 micron. The disk is resolved at 70, 160 and 450 micron. In addition to the planetesimal belt, we detect thermal emission from AU Mic's halo for the first time. In contrast to the scattered light images, no asymmetries are evident in the disk. The fractional luminosity of the disk is $3.9 \\times 10^{-4}$ and its mm-grain dust mass is 0.01 MEarth (+/- 20%). We create a simple spatial model that reconciles the disk SED as a blackbody of 53 +/- 2 K (a composite of 39 and 50 K components) and the presence of small (non-blackbody) grains which populate the extended halo. The best fit model is consistent with the "birth ring" model explored in earlier works, i.e., an edge-on dust belt extending from 8.8-40 AU, but with an additional halo component with an $r^{-1.5}$ surface density profile...

  4. Dust Dynamics and Surface Brightness Profiles of Debris Disks: The Case of AU Mic

    CERN Document Server

    Strubbe, L E; Strubbe, Linda E.; Chiang, Eugene I.

    2005-01-01

    AU Microscopii is a 12-Myr-old M dwarf that harbors an optically thin disk of dust. Within a projected distance b from the star of 43 AU--in the "inner disk"--the scattered-light surface brightness falls as b^-g, where g = 1-2. In the "outer disk," the brightness drops more steeply, with g = 4-5. We devise a theory to explain the entire profile, including the break. Our theory asserts that the AU Mic disk is in steady state and makes no recourse either to unequilibrated cataclysms or to preserved primordial conditions. We posit a ring of parent bodies on circular orbits near 43 AU: the "birth circle." At the birth circle, grains are produced by colliding parent bodies. Grains are removed by the star's wind and radiation, and by destructive grain-grain collisions. Grains having sizes just large enough to remain bound to the star occupy highly eccentric orbits and dominate scattering of starlight in the outer disk. We prove that for large stellocentric radius r, their surface density S scales as r^-5/2. Eccentr...

  5. Chelsea Boys: paradigmas sexuales de un cómic queer

    Directory of Open Access Journals (Sweden)

    Rafael Manuel Mérida Jiménez

    2009-01-01

    Full Text Available Más allá del barrio neoyorquino que da título a este serie de volúmenes –aunque en diálogo tanto con su realidad como con sus representaciones anteriores, como Rear Window, dónde se presenta ya como espacio sexualizado–; y más allá del estereotipo gay que la misma expresión representa, Chelsea Boys aparece como un espacio de ruptura de clichés. En el contexto del cómic gay norteamericano que se repasa en este artículo, constituye una propuesta plural, donde la universalidad de las situaciones que representa superan tanto el localismo como la rigidez estereotípica de algunas creaciones anteriores. En él emerge una comunidad queer a través de cuya representación se plantean cuestiones cruciales en y para la/s realidad/es gays.

  6. Extension of the AMBER molecular dynamics software to Intel's Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Needham, Perri J.; Bhuiyan, Ashraf; Walker, Ross C.

    2016-04-01

    We present an implementation of explicit solvent particle mesh Ewald (PME) classical molecular dynamics (MD) within the PMEMD molecular dynamics engine, that forms part of the AMBER v14 MD software package, that makes use of Intel Xeon Phi coprocessors by offloading portions of the PME direct summation and neighbor list build to the coprocessor. We refer to this implementation as pmemd MIC offload and in this paper present the technical details of the algorithm, including basic models for MPI and OpenMP configuration, and analyze the resultant performance. The algorithm provides the best performance improvement for large systems (>400,000 atoms), achieving a ∼35% performance improvement for satellite tobacco mosaic virus (1,067,095 atoms) when 2 Intel E5-2697 v2 processors (2 ×12 cores, 30M cache, 2.7 GHz) are coupled to an Intel Xeon Phi coprocessor (Model 7120P-1.238/1.333 GHz, 61 cores). The implementation utilizes a two-fold decomposition strategy: spatial decomposition using an MPI library and thread-based decomposition using OpenMP. We also present compiler optimization settings that improve the performance on Intel Xeon processors, while retaining simulation accuracy.

  7. MILLIMETER EMISSION STRUCTURE IN THE FIRST ALMA IMAGE OF THE AU Mic DEBRIS DISK

    International Nuclear Information System (INIS)

    We present 1.3 mm ALMA Cycle 0 observations of the edge-on debris disk around the nearby, ∼10 Myr old, M-type star AU Mic. These observations obtain 0.''6 (6 AU) resolution and reveal two distinct emission components: (1) the previously known dust belt that extends to a radius of 40 AU and (2) a newly recognized central peak that remains unresolved. The cold dust belt of mass ∼1 MMoon is resolved in the radial direction with a rising emission profile that peaks sharply at the location of the outer edge of the 'birth ring' of planetesimals hypothesized to explain the midplane scattered light gradients. No significant asymmetries are discerned in the structure or position of this dust belt. The central peak identified in the ALMA image is ∼6 times brighter than the stellar photosphere, which indicates an additional emission process in the inner regions of the system. Emission from a stellar corona or activity may contribute, but the observations show no signs of temporal variations characteristic of radio-wave flares. We suggest that this central component may be dominated by dust emission from an inner planetesimal belt of mass ∼0.01 MMoon, consistent with a lack of emission shortward of 25 μm and a location ∼<3 AU from the star. Future millimeter observations can test this assertion, as an inner dust belt should be readily separated from the central star at higher angular resolution.

  8. A Comparison of Antimicrobial Susceptibility and MIC-distributions in Enterococcus Isolates Originating from Humans, Animals and Retail Meat

    Science.gov (United States)

    Objectives: The National Antimicrobial Resistance Monitoring System (NARMS) is a collaborative effort between the Food and Drug Administration's Center for Veterinary Medicine (FDA CVM), U.S. Department of Agriculture (USDA), and the Centers for Disease Control and Prevention (CDC). The NARMS prog...

  9. Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI

    DEFF Research Database (Denmark)

    Tsai, Vicky Wang-Wei; Macia, Laurence; Feinle-Bisset, Christine;

    2015-01-01

    The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. This is mediated by a direct action of MIC-1/GDF15 on feeding centres in the...

  10. Clustering, haplotype diversity and locations of MIC-3: a unique root-specific defense-related gene family in upland cotton (Gossypium hirsutum L.)

    Science.gov (United States)

    MIC-3-related genes of cotton (Gossypium spp.) were identified and shown to have root-specific expression, associated with pathogen defense-related function and specifically increased expression in root-knot nematode (RKN) resistant plants after nematode infection. Here we cloned and sequenced MIC-...

  11. Potentials of plasma NGAL and MIC-1 as biomarker(s in the diagnosis of lethal pancreatic cancer.

    Directory of Open Access Journals (Sweden)

    Sukhwinder Kaur

    Full Text Available Pancreatic cancer (PC is lethal malignancy with very high mortality rate. Absence of sensitive and specific marker(s is one of the major factors for poor prognosis of PC patients. In pilot studies using small set of patients, secreted acute phase proteins neutrophil gelatinase associated lipocalin (NGAL and TGF-β family member macrophage inhibitory cytokine-1 (MIC-1 are proposed as most potential biomarkers specifically elevated in the blood of PC patients. However, their performance as diagnostic markers for PC, particularly in pre-treatment patients, remains unknown. In order to evaluate the diagnostic efficacy of NGAL and MIC-1, their levels were measured in plasma samples from patients with pre-treatment PC patients (n = 91 and compared it with those in healthy control (HC individuals (n = 24 and patients with chronic pancreatitis (CP, n = 23. The diagnostic performance of these two proteins was further compared with that of CA19-9, a tumor marker commonly used to follow PC progression. The levels of all three biomarkers were significantly higher in PC compared to HCs. The mean (± standard deviation, SD plasma NGAL, CA19-9 and MIC-1 levels in PC patients was 111.1 ng/mL (2.2, 219.2 U/mL (7.8 and 4.5 ng/mL (4.1, respectively. In comparing resectable PC to healthy patients, all three biomarkers were found to have comparable sensitivities (between 64%-81% but CA19-9 and NGAL had a higher specificity (92% and 88%, respectively. For distinguishing resectable PC from CP patients, CA19-9 and MIC-1 were most specific (74% and 78% respectively. CA19-9 at an optimal cut-off of 54.1 U/ml is highly specific in differentiating resectable (stage 1/2 pancreatic cancer patients from controls in comparison to its clinical cut-off (37.1 U/ml. Notably, the addition of MIC-1 to CA19-9 significantly improved the ability to distinguish resectable PC cases from CP (p = 0.029. Overall, MIC-1 in combination with CA19-9 improved the diagnostic

  12. MIX: a mosaic Asian anthropogenic emission inventory for the MICS-Asia and the HTAP projects

    Directory of Open Access Journals (Sweden)

    M. Li

    2015-12-01

    Full Text Available An anthropogenic emission inventory for Asia is developed for the years 2008 and 2010 to support the Model Inter-Comparison Study for Asia (MICS-Asia and the Task Force on Hemispheric Transport of Air Pollution (TF HTAP projects by a mosaic of up-to-date regional emission inventories. Emissions are estimated for all major anthropogenic sources in 30 countries and regions in Asia. We conducted detailed comparisons of different regional emission inventories and incorporated the best-available ones for each region into the mosaic inventory at a uniform spatial and temporal resolution. We estimate the total Asian emissions of ten species in 2010 as follows: 51.3 Tg SO2, 52.1 Tg NOx, 336.6 Tg CO, 67.0 Tg NMVOC (non-methane volatile organic compounds, 28.8 Tg NH3, 31.7 Tg PM10, 22.7 Tg PM2.5, 3.5 Tg BC, 8.3 Tg OC and 17.3 Pg CO2. Emissions from China and India dominate the emissions of Asia for most of the species. We also estimated Asian emissions in 2006 using the same methodology of MIX. The relative change rates of Asian emissions for the period of 2006–2010 are estimated as follows: −8.0 % for SO2, +19 % for NOx, +4 % for CO, +15 % for NMVOC, +2 % for NH3, −3 % for PM10, −2 % for PM2.5, +6 % for BC, +2 % for OC and +20 % for CO2. Model-ready speciated NMVOC emissions for SAPRC-99 and CB05 mechanisms were developed following a profile-assignment approach. Monthly gridded emissions at a spatial resolution of 0.25° × 0.25° are developed and can be accessed from http://www.meicmodel.org/dataset-mix.

  13. MILLIMETER EMISSION STRUCTURE IN THE FIRST ALMA IMAGE OF THE AU Mic DEBRIS DISK

    Energy Technology Data Exchange (ETDEWEB)

    MacGregor, Meredith A.; Wilner, David J.; Rosenfeld, Katherine A.; Andrews, Sean M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Matthews, Brenda; Booth, Mark [Herzberg Institute of Astrophysics, 5072 West Saanich Road, Victoria, BC V9E 2E7 (Canada); Hughes, A. Meredith; Chiang, Eugene; Graham, James R.; Kalas, Paul [Department of Astronomy, 601 Campbell Hall, University of California, Berkeley, CA 94720 (United States); Kennedy, Grant [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom); Sibthorpe, Bruce [SRON Netherlands Institute for Space Research, NL-9747 AD Groningen (Netherlands)

    2013-01-10

    We present 1.3 mm ALMA Cycle 0 observations of the edge-on debris disk around the nearby, {approx}10 Myr old, M-type star AU Mic. These observations obtain 0.''6 (6 AU) resolution and reveal two distinct emission components: (1) the previously known dust belt that extends to a radius of 40 AU and (2) a newly recognized central peak that remains unresolved. The cold dust belt of mass {approx}1 M{sub Moon} is resolved in the radial direction with a rising emission profile that peaks sharply at the location of the outer edge of the 'birth ring' of planetesimals hypothesized to explain the midplane scattered light gradients. No significant asymmetries are discerned in the structure or position of this dust belt. The central peak identified in the ALMA image is {approx}6 times brighter than the stellar photosphere, which indicates an additional emission process in the inner regions of the system. Emission from a stellar corona or activity may contribute, but the observations show no signs of temporal variations characteristic of radio-wave flares. We suggest that this central component may be dominated by dust emission from an inner planetesimal belt of mass {approx}0.01 M{sub Moon}, consistent with a lack of emission shortward of 25 {mu}m and a location {approx}<3 AU from the star. Future millimeter observations can test this assertion, as an inner dust belt should be readily separated from the central star at higher angular resolution.

  14. Rapid, Low-Technology MIC Determination with Clinical Mycobacterium tuberculosis Isolates by Using the Microplate Alamar Blue Assay

    OpenAIRE

    Franzblau, Scott G.; Witzig, Richard S.; McLaughlin, James C.; Torres, Patricia; Madico, Guillermo; Hernandez, Antonio; Degnan, Michelle T.; Cook, Mary B.; Quenzer, Virginia K.; Ferguson, Robert M.; Gilman, Robert H.

    1998-01-01

    A colorimetric, microplate-based Alamar Blue assay (MABA) method was used to determine the MICs of isoniazid (INH), rifampin, streptomycin (SM), and ethambutol (EMB) for 34 Peruvian Mycobacterium tuberculosis isolates (including both pansensitive and multidrug-resistant strains) and the H37Rv strain by using bacterial suspensions prepared directly from solid media. Results for all isolates were available within 8 days. Discordant results were observed on initial tests for 3 of 16 INH-suscepti...

  15. Focus sur le Centre d’information et de monitoring de la Commission européenne (MIC)1

    OpenAIRE

    2009-01-01

    Le mécanisme de protection civile de la Commission européenne est coordonné par le MIC (Monitoring and Information Centre, Centre d’information et de monitoring) qui permet à l’Union de répondre aux urgences de type catastrophes naturelles en mobilisant de façon coordonnée les protections civiles des Etats membres qui le souhaitent

  16. The BinaMIcS project: understanding the origin of magnetic fields in massive stars through close binary systems

    OpenAIRE

    Alecian, E.; Neiner, C.; Wade, G. A.; Mathis, S.; Bohlender, D.; Cébron, D; Folsom, C.; Grunhut, J.; Bouquin, J. -B. Le; Petit, V.; Sana, H.; Tkachenko, A.; ud-Doula, A.; collaboration, the BinaMIcS

    2014-01-01

    It is now well established that a fraction of the massive (M>8 Msun) star population hosts strong, organised magnetic fields, most likely of fossil origin. The details of the generation and evolution of these fields are still poorly understood. The BinaMIcS project takes an important step towards the understanding of the interplay between binarity and magnetism during the stellar formation and evolution, and in particular the genesis of fossil fields, by studying the magnetic properties of cl...

  17. AtMic60 Is Involved in Plant Mitochondria Lipid Trafficking and Is Part of a Large Complex.

    Science.gov (United States)

    Michaud, Morgane; Gros, Valérie; Tardif, Marianne; Brugière, Sabine; Ferro, Myriam; Prinz, William A; Toulmay, Alexandre; Mathur, Jaideep; Wozny, Michael; Falconet, Denis; Maréchal, Eric; Block, Maryse A; Jouhet, Juliette

    2016-03-01

    The mitochondrion is an organelle originating from an endosymbiotic event and playing a role in several fundamental processes such as energy production, metabolite syntheses, and programmed cell death. This organelle is delineated by two membranes whose synthesis requires an extensive exchange of phospholipids with other cellular organelles such as endoplasmic reticulum (ER) and vacuolar membranes in yeast. These transfers of phospholipids are thought to occur by a non-vesicular pathway at contact sites between two closely apposed membranes. In plants, little is known about the biogenesis of mitochondrial membranes. Contact sites between ER and mitochondria are suspected to play a similar role in phospholipid trafficking as in yeast, but this has never been demonstrated. In contrast, it has been shown that plastids are able to transfer lipids to mitochondria during phosphate starvation. However, the proteins involved in such transfer are still unknown. Here, we identified in Arabidopsis thaliana a large lipid-enriched complex called the mitochondrial transmembrane lipoprotein (MTL) complex. The MTL complex contains proteins located in the two mitochondrial membranes and conserved in all eukaryotic cells, such as the TOM complex and AtMic60, a component of the MICOS complex. We demonstrate that AtMic60 contributes to the export of phosphatidylethanolamine from mitochondria and the import of galactoglycerolipids from plastids during phosphate starvation. Furthermore, AtMic60 promotes lipid desorption from membranes, likely as an initial step for lipid transfer, and binds to Tom40, suggesting that AtMic60 could regulate the tethering between the inner and outer membranes of mitochondria. PMID:26898467

  18. Postantibiotic Effect and Postantibiotic Sub-MIC Effect of Quinupristin-Dalfopristin against Gram-Positive and -Negative Organisms

    OpenAIRE

    Pankuch, Glenn A.; Jacobs, Michael R.; Appelbaum, Peter C.

    1998-01-01

    Quinupristin-dalfopristin produced postantibiotic effects (PAEs) and postantibiotic sub-MIC effects of >2 h against 18 gram-positive cocci. Mean pneumococcal and staphylococcal PAEs were 2.8 and 4.7 h, respectively, with shorter PAEs for constitutively than inducibly macrolide-resistant staphylococci. Mean PAEs for vancomycin-susceptible and -resistant Enterococcus faecium were 8.5 and 2.6 h, respectively.

  19. Development of Doxycycline MIC and Disk Diffusion Interpretive Breakpoints and Revision of Tetracycline Breakpoints for Streptococcus pneumoniae

    OpenAIRE

    Dallas, Steven D.; McGee, Lesley; Limbago, Brandi; Patel, Jean B; McElmeel, M. Leticia; Fulcher, Letitia C.; Lonsway, David R.; Jorgensen, James H.

    2013-01-01

    A study was performed to derive susceptibility testing interpretive breakpoints for doxycycline with Streptococcus pneumoniae and to reassess breakpoints for tetracycline using the requirements defined in Clinical and Laboratory Standards Institute (CLSI) document M23-A3. Tetracycline and doxycycline MICs and disk diffusion zone sizes were determined on 189 isolates selected from the 2009-2010 CDC Active Bacterial Core surveillance strain collection according to the testing methods described ...

  20. Chlorhexidine resistance in methicillin-resistant Staphylococcus aureus or just an elevated MIC? An in vitro and in vivo assessment.

    OpenAIRE

    Cookson, B D; Bolton, M C; Platt, J H

    1991-01-01

    Chlorhexidine (Hibiscrub; ICI) is generally accepted to be effective as an antiseptic hand wash for methicillin-susceptible Staphylococcus aureus (MSSA), but there is dispute whether the chlorhexidine MIC for methicillin-resistant S. aureus (MRSA) strains is higher than that for MSSA strains and, indeed, whether it is relevant. In addition, the link between resistance to chlorhexidine, gentamicin, and "nucleic acid-binding" compounds (NAB; which code, in particular, for propamidine isethionat...

  1. GC-MS identification of MIC trimer: a constituent of tank residue in preserved autopsy blood of Bhopal gas victims.

    Science.gov (United States)

    Chandra, H; Rao, G J; Saraf, A K; Sharma, V K; Jadhav, R K; Sriramachari, S

    1991-10-01

    Based on the external and internal findings of Bhopal gas disaster victims, it was apparent that the gases and particulate matter came out as an aerosol. This was possibly the pyrolysed, reformulated, reconjugated suspension of constituents of the tank E-610 of Union Carbide India Limited, Bhopal, while it was claimed to be methyl isocyanate (MIC) only. It was postulated by the manufacturer of MIC, that the material inhaled by the victims of the Bhopal gas disaster does not cross the lung barrier (UCC press conference on 14th December 1984). It was observed that the more the victims ran, the more aerosol they inhaled and the fatalities were observed in such victims. The tissues, which were preserved in the deep freeze, were randomly selected and analysed by GC coupled with MS (ITD) Finnigan MAT, UK. 14 out of 34 autopsy cases showed MIC trimer peak in extracts of blood. This was one of the constituents of the aerosol and was also located in the tank residue, thereby proving that the trimer had passed the lung barrier. PMID:1795611

  2. LiF Reduces MICs of Antibiotics against Clinical Isolates of Gram-Positive and Gram-Negative Bacteria

    Directory of Open Access Journals (Sweden)

    H. C. Syed

    2012-01-01

    Full Text Available Antibiotic resistance is an ever-growing problem yet the development of new antibiotics has slowed to a trickle, giving rise to the use of combination therapy to eradicate infections. The purpose of this study was to evaluate the combined inhibitory effect of lithium fluoride (LiF and commonly used antimicrobials on the growth of the following bacteria: Enterococcus faecalis, Staphyloccoccus aureus, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, Serratia marcescens, and Streptococcus pneumoniae. The in vitro activities of ceftazidime, sulfamethoxazole-trimethoprim, streptomycin, erythromycin, amoxicillin, and ciprofloxacin, doxycycline, alone or combined with LiF were performed by microdilution method. MICs were determined visually following 18–20 h of incubation at 37°C. We observed reduced MICs of antibiotics associated with LiF ranging from two-fold to sixteen-fold. The strongest decreases of MICs observed were for streptomycin and erythromycin associated with LiF against Acinetobacter baumannii and Streptococcus pneumoniae. An eight-fold reduction was recorded for streptomycin against S. pneumoniae whereas an eight-fold and a sixteen-fold reduction were obtained for erythromycin against A. baumannii and S. pneumoniae. This suggests that LiF exhibits a synergistic effect with a wide range of antibiotics and is indicative of its potential as an adjuvant in antibiotic therapy.

  3. Discovery and characterization of the first non-coding RNA that regulates gene expression,micF RNA:A historical perspective

    Institute of Scientific and Technical Information of China (English)

    Nicholas; Delihas

    2015-01-01

    The first evidence that RNA can function as a regulator of gene expression came from experiments with prokaryotes in the 1980 s. It was shown that Escherichia coli micF isan independent gene,has its own promoter,and encodes a small non-coding RNA that base pairs with and inhibits translation of a target messenger RNA in response to environmental stress conditions. The mic F RNA was isolated,sequenced and shown to be a primary transcript. In vitro experiments showed binding to the target ompF mR NA. Secondary structure probing revealed an imperfect micF RNA/ompF RNA duplex interaction and the presence of a non-canonical base pair. Several transcription factors,including OmpR,regulate micF transcription in response to environmental factors. micF has also been found in other bacterial species,however,recently Gerhart Wagner and J?rg Vogel showed pleiotropic effects and found micF inhibits expression of multiple target mR NAs; importantly,one is the global regulatory gene lrp. In addition,micF RNA was found to interact with its targets in different ways; it either inhibits ribosome binding or induces degradation of the message. Thus the concept and initial experimental evidence that RNA can regulate gene expression was born with prokaryotes.

  4. Macrophage Inhibitory Cytokine-1 (MIC-1 as A Biomarker for Diagnosis 
and Prognosis of Stage I-II Non-small Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Yuning LIU

    2016-04-01

    Full Text Available Background and objective Increased macrophage inhibitory cytokine-1 (MIC-1, member of transforming growth factor-β (TGF-β superfamily, was found in patients serum with epithelial tumors. Therefore, our aim was to delineate the diagnostic and prognostic value of serum MIC-1 in patients with stage I-II non-small cell lung cancer (NSCLC. Methods A total of 152 consecutive patients with stage I–II NSCLC were prospectively enrolled and underwent follow up after total resection of tumor. Serum MIC-1 level was detected in lung cancer patients by ELISA, 48 benign pulmonary disease patients and 105 healthy controls, and was correlated with clinical features and prognosis of patients. Results The level of MIC-1 of NSCLC patients was significantly higher than that of controls (P<0.001 and benign pulmonary disease patients (P<0.001. A threshold of 1,000 pg/mL could be used to diagnose early-stage NSCLC with 70.4% sensitivity and 99.0% specificity. The level of MIC-1 was associated with elder age (P=0.001, female (P=0.03 and T2 (P=0.022. A threshold of 1,465 pg/mL could identify patients with early poor outcome with 72.2% sensitivity and 66.1% specificity. The overall 3-year survival rate in patients with high level of MIC-1 (≥1,465 pg/mL was significantly lower than that of patients with low MIC-1 level (77.6% vs 94.8%. Multivariable Cox regression revealed that a high level of MIC-1 was an independent risk factor for compromised overall survival (HR=3.37, 95%CI: 1.09-10.42, P=0.035. Conclusion High level of serum MIC-1 could be served as a potential biomarker for diagnosis and poorer outcome in patients with early-stage NSCLC.

  5. Association between the AUC0-24/MIC Ratio of Vancomycin and Its Clinical Effectiveness: A Systematic Review and Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Peng Men

    Full Text Available A target AUC0-24/MIC ratio of 400 has been associated with its clinical success when treating Staphylococcus aureus infections but is not currently supported by state-of-the-art evidence-based research.This current systematic review aimed to evaluate the available evidence for the association between the AUC0-24/MIC ratio of vancomycin and its clinical effectiveness on hospitalized patients and to confirm the existing target value of 400.PubMed, Embase, Web of Sciences, the Cochrane Library and two Chinese literature databases (CNKI, CBM were systematically searched. Manual searching was also applied. Both RCTs and observational studies comparing the clinical outcomes of high AUC0-24/MIC groups versus low AUC0-24/MIC groups were eligible. Two reviewers independently extracted the data. The primary outcomes were mortality and infection treatment failure. Risk ratios (RRs with 95% confidence intervals (95%CIs were calculated.No RCTs were retrieved. Nine cohort studies were included in the meta-analysis. Mortality rates were significantly lower in high AUC0-24/MIC groups (RR = 0.47, 95%CI = 0.31-0.70, p<0.001. The rates of infection treatment failure were also significantly lower in high AUC/MIC groups and were consistent after correcting for heterogeneity (RR = 0.39, 95%CI = 0.28-0.55, p = 0.001. Subgroup analyses showed that results were consistent whether MIC values were determined by broth microdilution (BMD method or Etest method. In studies using the BMD method, breakpoints of AUC0-24/MIC all fell within 85% to 115% of 400.This meta-analysis demonstrated that achieving a high AUC0-24/MIC of vancomycin could significantly decrease mortality rates by 53% and rates of infection treatment failure by 61%, with 400 being a reasonable target.

  6. La diversidad afectivo-sexual en el cómic: material didáctico para el ámbito educativo

    OpenAIRE

    Soler Quílez, Guillermo

    2015-01-01

    La siguiente propuesta pretende utilizar el recurso del cómic como instrumento didáctico recurrente en los diferentes ámbitos del sistema educativo, con especial incidencia en enseñanza secundaria y la universidad. El mundo del cómic resulta un instrumento atractivo para trabajar la diversa realidad afectivo-sexual de la sociedad actual. Se pretende seleccionar algunos de los cómics más significativos en los tres ámbitos más destacados: el manga japonés, con sus manifestaciones yaoi y yuri, e...

  7. In vitro antimicrobial activity and MIC quality control guidelines of RPR 106972 (RPR 112808/RPR106950): a novel orally administered streptogramin combination. The Quality Control Study Group.

    Science.gov (United States)

    Putnam, S D; Jones, R N; Johnson, D M

    1997-07-01

    RPR 106972 is a novel oral streptogramin combination with reported therapeutic potency against Gram-positive and certain respiratory tract pathogens. MICs for RPR 106972, quinupristin/dalfopristin, and seven comparison drugs were determined by the reference methods against 337 strains selected to define spectrum and potency. RPR 106972 demonstrated antimicrobial activity against oxacillin-susceptible and -resistant Staphylococcus aureus (MIC ranges of 0.12 to 2 micrograms/ml and 0.5 to 2 micrograms/ml, respectively), and coagulase-negative staphylococci were also inhibited by RPR 106972 (MIC90, pharmacokinetics, and in vivo infection model dynamics. PMID:9294704

  8. Extraction and ion exchange equilibrium. A study by means logarith-mic diagrams

    International Nuclear Information System (INIS)

    A general logarithmic mole fraction diagram for the study of distribution equilibria of a) a neutral chemical species between two inmiscible solvents and b) and ionic species between an aqueous phase and ion-exchange resin, is proposed. (Author)

  9. The relationship between inhibition of bacterial adhesion to a solid surface by sub-MICs of antibiotics and subsequent development of a biofilm

    OpenAIRE

    Cerca, Nuno; Martins, Silvia; Pier, Gerald B.; Oliveira, Rosário; Azeredo, Joana

    2005-01-01

    Many studies have demonstrated that subminimal inhibitory concentrations (sub-MICs) of antibiotics can inhibit initial microbial adherence to medical device surfaces. It has been suggested that, by inhibiting initial adhesion, biofilm formation might be prevented. However, since initial adherence and subsequent biofilm formation may be two distinct phenomena, conclusions regarding the effects of sub-MIC antibiotics on initial adhesion cannot be extrapolated to biofilm formation. In t...

  10. Microbial induced corrosion (MIC) on DHP copper by Desulfovibrio desulfuricans and Bacillus megaterium strains in media simulating heater waters

    International Nuclear Information System (INIS)

    The complexity and diversity of microbial populations in water heating systems of steam generators make it necessary to study the magnitude of the metabolic activity of bacteria and biofilm development that may lead to degradation of metal components through microbial induced corrosion (MIC). Electrolytes simulating the conditions found in heater water networks were used to induce biofilm formation on DHP copper coupons by Desulfovibrio desulfuricans DSMZ and Bacillus megaterium C10, a commercial strain and an isolate from these waters, respectively. In order to enhance their action, industrial waters enriched with the minimum nutrient content such as sodium lactate and sodium sulphite for the DSMZ strain and glucose, proteose peptone and starch for the C10 strain were employed. Biofilm formation was studied under controlled temperature, time, shaking, pH and concentrations of the media used in this study. Then, the samples were electrochemically tested in an artificial solution of sea water as control medium, based on the hypothesis that the action of an aggressive biofilm/electrolyte medium generates damaged and non-damaged areas on the metal surface, and assuming that the sea water trial can detect the latter. Hence, a higher anodic current was associated with a lower degradation of the metal surface by the action of one of the media under study. All these trials were performed along with bacterial count, scanning electron microscopy (SEM) and atomic absorption spectroscopy (AAS). Furthermore, it was possible to identify under which conditions MIC on DHP copper occurred and complex mechanisms from retention of cations to diffusion processes at the biofilm/tested media interface level were proposed. Surface corrosion by MIC took place on DHP copper; therefore, greater control on the treatment of industrial waters is highly desirable. (author)

  11. Microbial induced corrosion (MIC) on DHP copper by Desulfovibrio desulfuricans and Bacillus megaterium strains in media simulating heater waters

    Energy Technology Data Exchange (ETDEWEB)

    Zumelzu, E.; Cabezas, C.; Schoebitz, R.; Ugarte, R.; Rodriguez, E.D.; Rios, J. [Universidad Austral de Chile, Valdivia (Chile)

    2003-01-01

    The complexity and diversity of microbial populations in water heating systems of steam generators make it necessary to study the magnitude of the metabolic activity of bacteria and biofilm development that may lead to degradation of metal components through microbial induced corrosion (MIC). Electrolytes simulating the conditions found in heater water networks were used to induce biofilm formation on DHP copper coupons by Desulfovibrio desulfuricans DSMZ and Bacillus megaterium C10, a commercial strain and an isolate from these waters, respectively. In order to enhance their action, industrial waters enriched with the minimum nutrient content such as sodium lactate and sodium sulphite for the DSMZ strain and glucose, proteose peptone and starch for the C10 strain were employed. Biofilm formation was studied under controlled temperature, time, shaking, pH and concentrations of the media used in this study. Then, the samples were electrochemically tested in an artificial solution of sea water as control medium, based on the hypothesis that the action of an aggressive biofilm/electrolyte medium generates damaged and non-damaged areas on the metal surface, and assuming that the sea water trial can detect the latter. Hence, a higher anodic current was associated with a lower degradation of the metal surface by the action of one of the media under study. All these trials were performed along with bacterial count, scanning electron microscopy (SEM) and atomic absorption spectroscopy (AAS). Furthermore, it was possible to identify under which conditions MIC on DHP copper occurred and complex mechanisms from retention of cations to diffusion processes at the biofilm/tested media interface level were proposed. Surface corrosion by MIC took place on DHP copper; therefore, greater control on the treatment of industrial waters is highly desirable. (author)

  12. La vida imaginaria del científico. El caso del cómic 'The Manhattan Projects'

    OpenAIRE

    Sáez de Adana Herrero, Francisco

    2014-01-01

    Aquest article analitza The Manhattan Projects, sèrie de còmics que explica una història alternativa sobre el final de la Segona Guerra Mundial en què el Projecte Manhattan amaga altres activitats més relacionades amb la ciència-ficció. Aquest treball analitza la translació del concepte de vida imaginària encunyat per Marcel Schwob a la història de la ciència en el segle XX.

  13. Comparative Bacteriological Efficacy of Pharmacokinetically Enhanced Amoxicillin-Clavulanate against Streptococcus pneumoniae with Elevated Amoxicillin MICs and Haemophilus influenzae

    OpenAIRE

    Berry, Valerie; Hoover, Jennifer; Singley, Christine; Woodnutt, Gary

    2005-01-01

    A new pharmacokinetically enhanced formulation of amoxicillin-clavulanate (2,000 mg of amoxicillin/125 mg of clavulanate twice a day; ratio 16:1) has been designed, with sustained-release technology, to allow coverage of bacterial strains with amoxicillin-clavulanic acid MICs of at least 4/2 μg/ml. The bacteriological efficacy of amoxicillin-clavulanate, 2,000/125 mg twice a day, ratio 16:1, was compared in a rat model of respiratory tract infection versus four other amoxicillin-clavulanate f...

  14. La intertextualidad en el cine de Álex de la Iglesia:El caso del cómic

    OpenAIRE

    Neftalí Pérez Franco

    2010-01-01

    Este artículo repasa la influencia del tebeo en las películas del director vasco, Alex de la Iglesia, cuyas primeras obras artísticas se deben a su condición de joven autor de historietas. El cine de este cineasta está marcado por claras reminiscencias provenientes de las viñetas: los superhéroes patéticos de Acción mutante se mueven por un contexto futurista muy del cómic de ciencia ficción; el humor estereotipado y los personajes grotescos del tebeo de la editorial Bruguera inundan todas su...

  15. Regulació motivacional, satisfacció i rendiment acadèmic dels estudiants de psicologia

    OpenAIRE

    Moral Roig, Agnès; Pallisera Herrero, Yanira; Santaló Jurado, Estefania; Gras Pérez, María Eugenia; Villar, Esperança

    2008-01-01

    Aquest estudi aplica la Teoria de l‟Autodeterminació (Deci i Ryan, 1985, 2000, 2002) i el constructe motivacional d‟Engagement (Schaufeli, Martínez, Marqués, Salanova i Bakker, 2002; Schaufeli, Salanova, González-Roma i Bakker, 2002) per investigar els efectes de la regulació motivacional dels estudiants, l‟Engagement, la Competència percebuda i la Vinculació sobre les Expectatives Acadèmiques i Laborals, la Satisfacció i el Rendiment acadèmic. Els resultats revelen que: (1) els 214 estudiant...

  16. Birds on a wire: empirical studies of flocking dyna-mics in linear aggregates

    Science.gov (United States)

    Schwartz, Elliott; Fulton, Andrew; Rosenthal, Lee; Kane, Suzanne Amador

    2014-03-01

    The dynamics of avian flocking is difficult to study because of the transient, highly mobile and unpredictable nature of bird flocks. However, birds often form clusters when perched on wires and fences, offering a stable platform for studying the formation, internal structure and dynamics of these approximately one-dimensional flocks. Previous studies have examined the distribution of the distances between birds perched on wires, but not the time-dependence of this behavior. We present results from a video study of cliff swallows (Petrochelidon pyrrhonota) perched on power lines in Sierra Valley, California. Phenomena studied include how the interbird distance distribution varies as a function of time, what factors influence the addition of further birds to an existing cluster, how the distribution evolves in response to perturbations, and typical timescales for the observed behaviors.

  17. Evaluation of Oxacillin and Cefoxitin Disk and MIC Breakpoints for Prediction of Methicillin Resistance in Human and Veterinary Isolates of Staphylococcus intermedius Group.

    Science.gov (United States)

    Wu, M T; Burnham, C-A D; Westblade, L F; Dien Bard, J; Lawhon, S D; Wallace, M A; Stanley, T; Burd, E; Hindler, J; Humphries, R M

    2016-03-01

    Staphylococcus pseudintermedius is a coagulase-positive species that colonizes the nares and anal mucosa of healthy dogs and cats. Human infections with S. pseudintermedius range in severity from bite wounds and rhinosinusitis to endocarditis; historically, these infections were thought to be uncommon, but new laboratory methods suggest that their true incidence is underreported. Oxacillin and cefoxitin disk and MIC tests were evaluated for the detection of mecA- or mecC-mediated methicillin resistance in 115 human and animal isolates of the Staphylococcus intermedius group (SIG), including 111 Staphylococcus pseudintermediusand 4 Staphylococcus delphini isolates, 37 of which were mecA positive. The disk and MIC breakpoints evaluated included the Clinical and Laboratory Standards Institute (CLSI) M100-S25 Staphylococcus aureus/Staphylococcus lugdunensis oxacillin MIC breakpoints and cefoxitin disk and MIC breakpoints, the CLSI M100-S25 coagulase-negative Staphylococcus (CoNS) oxacillin MIC breakpoint and cefoxitin disk breakpoint, the CLSI VET01-S2 S. pseudintermedius oxacillin MIC and disk breakpoints, and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) S. pseudintermedius cefoxitin disk breakpoint. The oxacillin results interpreted by the VET01-S2 (disk and MIC) and M100-S25 CoNS (MIC) breakpoints agreed with the results of mecA/mecC PCR for all isolates, with the exception of one false-resistant result (1.3% of mecA/mecC PCR-negative isolates). In contrast, cefoxitin tests performed poorly, ranging from 3 to 89% false susceptibility (very major errors) and 0 to 48% false resistance (major errors). BD Phoenix, bioMérieux Vitek 2, and Beckman Coulter MicroScan commercial automated susceptibility test panel oxacillin MIC results were also evaluated and demonstrated >95% categorical agreement with mecA/mecC PCR results if interpreted by using the M100-S25 CoNS breakpoint. The Alere penicillin-binding protein 2a test accurately detected all

  18. Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay.

    Science.gov (United States)

    Franzblau, S G; Witzig, R S; McLaughlin, J C; Torres, P; Madico, G; Hernandez, A; Degnan, M T; Cook, M B; Quenzer, V K; Ferguson, R M; Gilman, R H

    1998-02-01

    A colorimetric, microplate-based Alamar Blue assay (MABA) method was used to determine the MICs of isoniazid (INH), rifampin, streptomycin (SM), and ethambutol (EMB) for 34 Peruvian Mycobacterium tuberculosis isolates (including both pansensitive and multidrug-resistant strains) and the H37Rv strain by using bacterial suspensions prepared directly from solid media. Results for all isolates were available within 8 days. Discordant results were observed on initial tests for 3 of 16 INH-susceptible isolates, 5 of 31 EMB-susceptible isolates, and 2 of 4 SM-resistant isolates (by the BACTEC 460 system). The overall agreements between the MICs obtained by MABA and the results obtained with the BACTEC 460 system were 87.9% for initial results and 93.6% after retesting 12 of 17 samples with discrepant results. Interpretation of MABA endpoints improved with technical experience. The MABA is a simple, rapid, low-cost, appropriate technology which does not require expensive instrumentation and which makes use of a nontoxic, temperature-stable reagent. PMID:9466742

  19. The BinaMIcS project: understanding the origin of magnetic fields in massive stars through close binary systems

    CERN Document Server

    Alecian, E; Wade, G A; Mathis, S; Bohlender, D; Cébron, D; Folsom, C; Grunhut, J; Bouquin, J -B Le; Petit, V; Sana, H; Tkachenko, A; ud-Doula, A

    2014-01-01

    It is now well established that a fraction of the massive (M>8 Msun) star population hosts strong, organised magnetic fields, most likely of fossil origin. The details of the generation and evolution of these fields are still poorly understood. The BinaMIcS project takes an important step towards the understanding of the interplay between binarity and magnetism during the stellar formation and evolution, and in particular the genesis of fossil fields, by studying the magnetic properties of close binary systems. The components of such systems are most likely formed together, at the same time and in the same environment, and can therefore help us to disentangle the role of initial conditions on the magnetic properties of the massive stars from other competing effects such as age or rotation. We present here the main scientific objectives of the BinaMIcS project, as well as preliminary results from the first year of observations from the associated ESPaDOnS and Narval spectropolarimetric surveys.

  20. The BinaMIcS project: understanding the origin of magnetic fields in massive stars through close binary systems

    Science.gov (United States)

    Alecian, E.; Neiner, C.; Wade, G. A.; Mathis, S.; Bohlender, D.; Cébron, D.; Folsom, C.; Grunhut, J.; Le Bouquin, J.-B.; Petit, V.; Sana, H.; Tkachenko, A.; ud-Doula, A.

    2015-01-01

    It is now well established that a fraction of the massive (M > 8 M ⊙) star population hosts strong, organised magnetic fields, most likely of fossil origin. The details of the generation and evolution of these fields are still poorly understood. The BinaMIcS project takes an important step towards the understanding of the interplay between binarity and magnetism during the stellar formation and evolution, and in particular the genesis of fossil fields, by studying the magnetic properties of close binary systems. The components of such systems are most likely formed together, at the same time and in the same environment, and can therefore help us to disentangle the role of initial conditions on the magnetic properties of the massive stars from other competing effects such as age or rotation. We present here the main scientific objectives of the BinaMIcS project, as well as preliminary results from the first year of observations from the associated ESPaDOnS and Narval spectropolarimetric surveys.

  1. GPU/MIC Acceleration of the LHC High Level Trigger to Extend the Physics Reach at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Halyo, Valerie [Princeton Univ., NJ (United States); Tully, Christopher [Princeton Univ., NJ (United States)

    2015-04-14

    The quest for rare new physics phenomena leads the PI [3] to propose evaluation of coprocessors based on Graphics Processing Units (GPUs) and the Intel Many Integrated Core (MIC) architecture for integration into the trigger system at LHC. This will require development of a new massively parallel implementation of the well known Combinatorial Track Finder which uses the Kalman Filter to accelerate processing of data from the silicon pixel and microstrip detectors and reconstruct the trajectory of all charged particles down to momentums of 100 MeV. It is expected to run at least one order of magnitude faster than an equivalent algorithm on a quad core CPU for extreme pileup scenarios of 100 interactions per bunch crossing. The new tracking algorithms will be developed and optimized separately on the GPU and Intel MIC and then evaluated against each other for performance and power efficiency. The results will be used to project the cost of the proposed hardware architectures for the HLT server farm, taking into account the long term projections of the main vendors in the market (AMD, Intel, and NVIDIA) over the next 10 years. Extensive experience and familiarity of the PI with the LHC tracker and trigger requirements led to the development of a complementary tracking algorithm that is described in [arxiv: 1305.4855], [arxiv: 1309.6275] and preliminary results accepted to JINST.

  2. Mastite micótica em ruminantes causada por leveduras Mycotic mastitis in ruminants caused by yeasts

    Directory of Open Access Journals (Sweden)

    Andréia Spanamberg

    2009-02-01

    Full Text Available A ocorrência de casos esporádicos de mastite causados por microrganismos de origem ambiental pode ser considerada como emergente e as leveduras, os fungos leveduriformes e os filamentosos são alguns dos principais agentes envolvidos. Em relação à mastite micótica, as leveduras são freqüentemente causas de infecções da glândula mamária em animais produtores de leite. A maior parte dos casos ocorre sob a forma de surtos localizados e/ou após tratamento com antimicrobianos. Os principais gêneros envolvidos são Candida e Cryptococcus, além de outros como Geotrichum, Pichia e Trichosporon. O objetivo do trabalho é revisar os aspectos gerais sobre a mastite micótica causada por leveduras e fungos leveduriformes, tais como etiologia, causas predisponentes, patogenicidade, diagnóstico, tratamento e profilaxia por meio de uma abordagem cronológica dos primeiros relatos, mas com enfoque principal nos resultados descritos recentemente na literatura veterinária nacional e internacional. O controle da mastite micótica é fundamentado em métodos preventivos, como adequado manejo da ordenha, correta higienização dos equipamentos e das instalações, com a finalidade de reduzir o número de animais acometidos, além de garantir a qualidade e a inocuidade dos produtos lácteos.The veterinary literature registers sporadic cases of infections caused by environmental microorganisms in which the main agents involved are yeasts, yeasts-like and filamentous fungi. In relation to dairy animals, the yeasts are more frequently incriminated as the aetiological agents of mycotic mastitis. Most cases occur under the form of localized outbreaks and / or after treatment with antimicrobial agents. The main genera involved in mastitis are Candida and Cryptococcus, besides others such as Geotrichum, Pichia and Trichosporon. The purpose of this review is to point out the main aspects of mastitis caused by yeasts and yeast-like fungi, such as etiology

  3. 3D-Spiral Small Antenna Design and Realization for Biomedical Telemetry in the MICS band

    Directory of Open Access Journals (Sweden)

    A. K. Skrivervik

    2009-12-01

    Full Text Available This work presents the design and realization procedure of small implantable antenna for biotelemetry applications. The radiator occupies a volume smaller than 3 cm3 (without its biocompatible insulation, is well matched within the Medical Implanted Communications System band and shows an adequate gain (-28.5 dB while introduced in the appropriate equivalent body medium. The latter is a homogeneous phantom with muscle dielectric properties. A prototype has been manufactured and measurements agree with theoretical predictions. Particular attention is paid to the building requirements such as the presence of glue. Specific Absorption Rate (SAR distribution has been computed evaluating the maximum power deliverable to the antenna in order to respect the regulated SAR limitation.

  4. Mito clásico y cultura popular : reminiscencias mitológicas en el cómic estadounidense

    OpenAIRE

    Unceta Gómez, Luis

    2007-01-01

    La profunda influencia de la mitología clásica en todos los ámbitos de creación artística tradicional es algo fuera de toda duda. Sin embargo, su presencia en otras manifestaciones contemporáneas de la llamada «cultura popular» no resulta tan evidente, quizá por haber recibido una menor atención. El presente trabajo propone una aproximación a la pervivencia del mito clásico en el cómic estadounidense de superhéroes, a través del análisis de algunos casos concretos.

  5. La rentabilidad del cómic en la enseñanza de la cultura en E/LE

    Directory of Open Access Journals (Sweden)

    Jaume Brines Gandía

    2012-01-01

    Full Text Available El presente trabajo trata sobre el uso del cómic como recurso didáctico en la clase de E/LE para enseñar cultura. Aunque la cultura en la clase de E/LE muchas veces pasa desapercibida, constituye un excelente instrumento para la enseñanza de la lengua extranjera y, sobre todo, para que el futuro aprendiente sepa cómo, cuándo y de qué modo usar la lengua. Antes de desarrollar la presente experiencia práctica, es necesario que tratemos el término cultura y las distintas acepciones que supone.

  6. Mathematical model for the growth of P. aeruginosa and four mutator strains in sub-MIC concentration of Ciprofloxacin

    DEFF Research Database (Denmark)

    Philipsen, Kirsten Riber; Christiansen, Lasse Engbo; Madsen, Henrik;

    . aeruginosa lung infection. Intensive antibiotic treatment has improved the survival and clinical condition of CF patients, but development of resistance to antibiotics makes these infections difficult to treat efficiently. Ciprofloxacin is commonly used in the early and aggressive treatment. A hypothesis is......M-mutY mutants) when growing under sub-MIC Ciprofloxacin concentration (0.1 μg/ml), in order to describe the growth pattern under the presence of antibiotic. Data available for the modelling process is bioscreen measurements of the bacterial content as a function of time for each bacteria strain growing in LB...... media with and without the presence of Ciprofloxacin. The growth of the bacteria strains is modelled with a continuous-discrete time stochastic state space model consisting of a continuous time state equation expressed as a system of stochastic differential equations and a discrete time measurement...

  7. Performance of a 100V Half-Bridge MOSFET Driver, Type MIC4103, Over a Wide Temperature Range

    Science.gov (United States)

    Patterson, Richard L.; Hammoud, Ahmad

    2011-01-01

    The operation of a high frequency, high voltage MOSFET (metal-oxide semiconductor field-effect transistors) driver was investigated over a wide temperature regime that extended beyond its specified range. The Micrel MIC4103 is a 100V, non-inverting, dual driver that is designed to independently drive both high-side and low-side N-channel MOSFETs. It features fast propagation delay times and can drive 1000 pF load with 10ns rise times and 6 ns fall times [1]. The device consumes very little power, has supply under-voltage protection, and is rated for a -40 C to +125 C junction temperature range. The floating high-side driver of the chip can sustain boost voltages up to 100 V. Table I shows some of the device manufacturer s specification.

  8. Rotational modulation and flares on RS CVn and BY Dra-type stars. I - Photometry and spot models for BY Dra, AU Mic, AR Lac, II Peg and V 711 Tau (= HR 1099)

    Science.gov (United States)

    Rodono, M.; Cutispoto, G.; Pazzani, V.; Catalano, S.; Byrne, P. B.

    1986-01-01

    Multicolor wide-band photometry of five active stars is presented. The observations were carried out at several places before, during and after the period of IUE observations for the purpose of determining the location, sizes, and evolution of photospheric spots at the time when chromospheric, transition region, and coronal activity data were obtained from UV and radio observations. II Peg, BY Dra, and AU Mic show fairly stable quasi-sinusoidal light curves, while AR Lac and V 711 Tau show double-peaked light curves. For V 711 Tau, a remarkable evolution of the spotted area extent and/or longitude distribution is found. Small, but definite color variations that are consistent with the cool spot hypothesis have also been detected for BY Dra, II Peg and V 711 Tau.

  9. Spectrophotometric Determination of Microamounts of Uranium previous Extraction with TBP-MIC; Determinacion Espectrofotometrica de Microcantidades de Uranio previa extraccin con Metilisobutilcetona-Fosfato de Tributilo

    Energy Technology Data Exchange (ETDEWEB)

    Vera Palomino, J.; Palomares Delgado, F.; Petrement, J.; Fernandez Cellini, R.

    1962-07-01

    Selective extraction of uranium in nitric acid medium with a mixture of Tbp-MIC (1:10) has been achieved. Aluminium nitrate was used as salting agent. Complexing agents were added in order to avoid extraction of impurities. Extraction conditions have been studied so that extraction is almost practically complete in a single run. (Author) 19 refs.

  10. XML In Vitro Comparison of MIC Crude Extracts of Active Actinomycetes Isolated with Terbinafine, Griseofulvin Ketoconazole and Fluconazole against Microsporum Canis, Microsporum Gypseum and Trichophyton Mentagrophytes

    Directory of Open Access Journals (Sweden)

    Keikha, N. (MSc

    2015-05-01

    Full Text Available Background and Objective: Dermatophytes are the fungi that have the ability to attack the keratinized tissues such as the skin, hair and nails. Infections caused by these organisms are named dermatophytosis. We aimed to compare Minimum inhibitory concentration (MIC of Crude extracts of Active Actinomycete Isolates with Terbinafine, Griseofulvin, Ketoconazole and Fluconazole Drugs against Microsporum Canis, Microsporum gypseum and Trichophyton mentagrophytes. Material and Methods: In this experimental study, in order to find MIC by actionmycete, 100 isolates were studied and then crude extracts of the active actinomycete isolates were prepared in sterile conditions. Finally, the crude extracts obtained at different concentrations were used to obtain the MIC of Microsporum Canis, Microsporum gypseum and Trichophyton mentagrophytes. Moreover, various concentrations of the drugs such as terbinafine, griseofulvin, ketoconazole and fluconazole in solvent Dimethyl sulfoxide (DMSO were prepared and their growth inhibitory effect was evaluated and then compared with the results obtained from the crude extract of active actinomycete isolates. Results: the crude extracts obtained from active Actioiomycetes isolates and the drugs such as terbinafine, griseofulvin, ketoconazole and fluconazole, in a dose-dependent manner, could inhibit the growth of Microsporum Canis, Microsporum gypseum and Trichophyton Mentagrophytes. Conclusion: compared to MIC of Crude extract of active actinomycete isolates, Terbinafine has a significant effect on the growth inhibition in all of the fungal Dermatophytes and then griseofulvin, ketoconazole and fluconazole are in the next rank, respectively.

  11. Rhodium, iridium and nickel complexes with a 1,3,5-triphenylbenzene tris-MIC ligand. Study of the electronic properties and catalytic activities

    Science.gov (United States)

    Mejuto, Carmen; Royo, Beatriz

    2015-01-01

    Summary The coordination versatility of a 1,3,5-triphenylbenzene-tris-mesoionic carbene ligand is illustrated by the preparation of complexes with three different metals: rhodium, iridium and nickel. The rhodium and iridium complexes contained the [MCl(COD)] fragments, while the nickel compound contained [NiCpCl]. The preparation of the tris-MIC (MIC = mesoionic carbene) complex with three [IrCl(CO)2] fragments, allowed the estimation of the Tolman electronic parameter (TEP) for the ligand, which was compared with the TEP value for a related 1,3,5-triphenylbenzene-tris-NHC ligand. The electronic properties of the tris-MIC ligand were studied by cyclic voltammetry measurements. In all cases, the tris-MIC ligand showed a stronger electron-donating character than the corresponding NHC-based ligands. The catalytic activity of the tri-rhodium complex was tested in the addition reaction of arylboronic acids to α,β-unsaturated ketones. PMID:26734104

  12. Rhodium, iridium and nickel complexes with a 1,3,5-triphenylbenzene tris-MIC ligand. Study of the electronic properties and catalytic activities

    Directory of Open Access Journals (Sweden)

    Carmen Mejuto

    2015-12-01

    Full Text Available The coordination versatility of a 1,3,5-triphenylbenzene-tris-mesoionic carbene ligand is illustrated by the preparation of complexes with three different metals: rhodium, iridium and nickel. The rhodium and iridium complexes contained the [MCl(COD] fragments, while the nickel compound contained [NiCpCl]. The preparation of the tris-MIC (MIC = mesoionic carbene complex with three [IrCl(CO2] fragments, allowed the estimation of the Tolman electronic parameter (TEP for the ligand, which was compared with the TEP value for a related 1,3,5-triphenylbenzene-tris-NHC ligand. The electronic properties of the tris-MIC ligand were studied by cyclic voltammetry measurements. In all cases, the tris-MIC ligand showed a stronger electron-donating character than the corresponding NHC-based ligands. The catalytic activity of the tri-rhodium complex was tested in the addition reaction of arylboronic acids to α,β-unsaturated ketones.

  13. Un acercamiento didáctico a la primera mitad del s. XX a través de los cómics

    OpenAIRE

    Becerra Romero, Daniel; Jorge Godoy, Soraya

    2014-01-01

    El cómic ha sido un recurso didáctico que, aunque conocido, se ha utilizado poco en el mundo de la enseñanza, sobre todo si tenemos en cuenta sus posibilidades. En el presente artículo nos hemos planteado un acercamiento a la Historia Contemporánea

  14. Toxoplasma gondii: Protective immunity induced by a DNA vaccine expressing GRA1 and MIC3 against toxoplasmosis in BALB/c mice.

    Science.gov (United States)

    Gong, Pengtao; Cao, Lili; Guo, Yanbing; Dong, Hang; Yuan, Shuxian; Yao, Xinhua; Ren, Wenzhi; Yao, Lin; Xu, Zhilin; Sun, Qiang; Zhang, Xichen

    2016-07-01

    The intracellular parasite Toxoplasma gondii is a major cause of abortion and neonatal loss in livestock, and can cause severe illness to human with weakened immune system. The heavy incidence and severe consequence indicate the development of vaccines against T. gondii is required. In this study, DNA vaccines encoding GRA1 and MIC3 antigens were developed. The parasite-specific immune responses and protection efficiency against toxoplasmosis by these DNA vaccines were evaluated in BALB/c mice. The results demonstrated that the IgG antibody production was significantly increased in multi-antigenic vaccine encoding GRA1 and MIC3 immunized group, as well as the IFN-γ level, when compared with single-gene vaccines and controls groups (p < 0.05). Two weeks after the final vaccination, the mice were challenged with either 1 × 10(4) or 1 × 10(2) RH strain tachyzoites, and the mortality and parasite reduction were observed. The multi-antigenic vaccine encoding GRA1 and MIC3 lead to the longest survival time as well as the less parasite-loads in brain and liver of immunized mice (p < 0.01). The present study indicates that the GRA1 and MIC3 showed the potential as target for vaccine investigation against toxoplasmosis. And the immune efficacy induced by multi-antigenic vaccine encoding GRA1 and MIC3 was better than that induced by single-antigenic vaccines alone. PMID:27059254

  15. La intertextualidad en el cine de Álex de la Iglesia:El caso del cómic

    Directory of Open Access Journals (Sweden)

    Neftalí Pérez Franco

    2010-10-01

    Full Text Available Este artículo repasa la influencia del tebeo en las películas del director vasco, Alex de la Iglesia, cuyas primeras obras artísticas se deben a su condición de joven autor de historietas. El cine de este cineasta está marcado por claras reminiscencias provenientes de las viñetas: los superhéroes patéticos de Acción mutante se mueven por un contexto futurista muy del cómic de ciencia ficción; el humor estereotipado y los personajes grotescos del tebeo de la editorial Bruguera inundan todas sus comedias; o también son destacables los diversos homenajes narrativos o estéticos a la escuela franco-belga de Hergé y Goscinny. Esta fuerte influencia recorre toda su filmografía desde la mencionada ópera prima Acción mutante, hasta Crimen Ferpecto, pasando por títulos como El día de la bestia, Perdita Durango, Muertos de risa o La comunidad, hasta convertirse en un autor abanderado del fenómeno freak que marca tendencia en el cine español.

  16. In silico docking of methyl isocyanate (MIC) and its hydrolytic product (1, 3-dimethylurea) shows significant interaction with DNA Methyltransferase 1 suggests cancer risk in Bhopal-Gas- Tragedy survivors.

    Science.gov (United States)

    Khan, Inbesat; Senthilkumar, Chinnu Sugavanam; Upadhyay, Nisha; Singh, Hemant; Sachdeva, Meenu; Jatawa, Suresh Kumar; Tiwari, Archana

    2015-01-01

    DNA methyltransferase 1 (DNMT1) is a relatively large protein family responsible for maintenance of normal methylation, cell growth and survival in mammals. Toxic industrial chemical exposure associated methylation misregulation has been shown to have epigenetic influence. Such misregulation could effectively contribute to cancer development and progression. Methyl isocyanate (MIC) is a noxious industrial chemical used extensively in the production of carbamate pesticides. We here applied an in silico molecular docking approach to study the interaction of MIC with diverse domains of DNMT1, to predict cancer risk in the Bhopal population exposed to MIC during 1984. For the first time, we investigated the interaction of MIC and its hydrolytic product (1,3-dimethylurea) with DNMT1 interacting (such as DMAP1, RFTS, and CXXC) and catalytic (SAM, SAH, and Sinefungin) domains using computer simulations. The results of the present study showed a potential interaction of MIC and 1,3-dimethylurea with these domains. Obviously, strong binding of MIC with DNMT1 interrupting normal methylation will lead to epigenetic alterations in the exposed humans. We suggest therefore that the MIC- exposed individuals surviving after 1984 disaster have excess risk of cancer, which can be attributed to alterations in their epigenome. Our findings will help in better understanding the underlying epigenetic mechanisms in humans exposed to MIC. PMID:26625778

  17. Sample preparation technique based on microwave-induced combustion (MIC) for further determination of halogens in elastomers

    International Nuclear Information System (INIS)

    Complete text of publication follows. Elastomers are considered apart from other polymeric materials in view of their special properties as elasticity, strength, stiffness, abrasion and tear resistance. Elastomers generally contains bromine and chlorine that could be responsible for same and problems related to environmental pollution (RoHS and WEEE directives) and should be currently determined in these materials. In spite of the spread and successful use of conventional microwave-assisted digestion for different matrices its application for subsequent halogens determination has some drawbacks as incomplete digestion and high residual acid concentration that could cause interferences in the determination step. Moreover, carbon black is currently added as additive for some elastomers in high levels making more difficult to achieve an effective digestion. In this work the microwave-induced combustion (MIC) technique was applied for digestion of nitrile-butadiene rubber (NBR) and ethylene-propylene-diene monomer (EPDM). The suitability of this technique was evaluated for the subsequent determination of Br and Cl in elastomers samples by ICP-OES and ICP-MS. Combustion was carried out in a quartz vessel pressurized with 20 bar of oxygen and 50 μL NH4NO3. After combustion analytes were absorbed in 50 mmol L-1 ammonium carbonate solution and a reflux step, if necessary, was applied in order to obtain a complete recovery of analytes. Bromine and Cl concentration was in the range of 0.1 to 1.0 μg g-1 and 150 to 500 μg g-1, respectively. Accuracy (better than 97%) was evaluated using certified reference materials. Up to 500 mg of sample can be completely combusted with residual carbon content lower than 1%. Up to eight samples can be simultaneously processed in 25 min making this technique suitable for routine analysis. The authors are grateful to CENPES/PETROBRAS, CAPES, and CNPq.

  18. Nuevo Orden Mundial. Narraciones sobre el poder y superhéroes en el cómic mainstream estadounidense de Stormwatch a Black Summer (1996-2008)

    OpenAIRE

    Hernández Cano, Eduardo

    2009-01-01

    Los cómics de superhéroes han sido estudiados por la crítica, sobre todo, como artefactos mitológicos de implicaciones morales y filosóficas. Pero desde finales de los noventa una parte importante del cómic de superhéroes mainstream se ha convertido en una narrativa simbólica sobre el poder en el mundo contemporáneo, alimentándose del discurso y los acontecimientos políticos, textualizando de manera sutil, política y moralmente provocadora, acontecimientos reales como el nuevo terrorismo y la...

  19. An investigation of microbial diversity in crude oil & seawater injection systems and microbiologically influenced corrosion (MIC) of linepipe steels under different exposure conditions

    Science.gov (United States)

    AlAbbas, Faisal Mohammed

    During oil and gas operations, pipeline networks are subjected to different corrosion deterioration mechanisms that result from the interaction between the fluid process and the linepipe steel. Among these mechanisms is microbiologically influenced corrosion (MIC) that results from accelerated deterioration caused by different indigenous microorganisms that naturally reside in the hydrocarbon and associated seawater injection systems. The focus of this research is to obtain comprehensive understanding of MIC. This work has explored the most essential elements (identifications, implications and mitigations) required to fully understand MIC. Advanced molecular-based techniques, including sequencing of 16S rRNA genes via 454 pyrosequencing methodologies, were deployed to provide in-depth understanding of the microbial diversity associated with crude oil and seawater injection systems and their relevant impact on MIC. Key microbes including sulfate reducing bacteria (SRB) and iron reducing bacteria (IRB) were cultivated from sour oil well field samples. The microbes' phylotypes were identified in the laboratory to gain more thorough understanding of how they impact microbial corrosion. Electrochemical and advanced surface analytical techniques were used for corrosion evaluations of linepipe carbon steels (API 5L X52 and X80) under different exposure conditions. On the identification front, 454 pyrosequencing of both 16S rRNA genes indicated that the microbial communities in the corrosion products obtained from the sour oil pipeline, sweet crude pipeline and seawater pipeline were dominated by bacteria, though archaeal sequences (predominately Methanobacteriaceae and Methanomicrobiaceae) were also identified in the sweet and sour crude oil samples, respectively. The dominant bacterial phylotypes in the sour crude sample included members of the Thermoanaerobacterales, Synergistales, and Syntrophobacterales. In the sweet crude sample, the dominant phylotypes included

  20. Disidencia sexual en el cómic alemán contemporáneo: el caso de Ralf König

    OpenAIRE

    Saxe, Facundo

    2016-01-01

    Este trabajo aborda la representación de la sexualidad disidente en el cómic alemán contemporáneo. Se analiza la obra del autor alemán Ralf König desde una perspectiva propia de los estudios queer y la disidencia de sexo-género. A través de un recorrido crítico se conceptualiza la figura del autor en su campo cultural y su proyección vinculada a las sexualidades disidentes en Europa y a la tradición del cómic en Alemania. Como caso paradigmático se realiza un análisis textual d...

  1. Comparrisson of MICs of ceftioufur and other antimicrobial agents against bacterial pathogens of swine from the United States, Canada and Denmark

    DEFF Research Database (Denmark)

    Salmon, S.A.; Watts, J.L.; Case, C.A.; Hoffmann, L.J.; Wegener, Henrik Caspar; Yancey, R.J.

    1995-01-01

    , Salmonella choleraesuis, Salmonella typhimurium, Streptococcus suis, Streptococcus dysgalactiae subsp. equisimilis, Streptococcus equi subsp. equi, and Streptococcus equi subsp. zooepidemicus. In addition to ceftiofur, the following antimicrobial agents or combinations were tested: enroflaxacin, ampicillin...... to 8.0, greater than or equal to 256.0, greater than or equal to 32.0, and greater than or equal to 16.0 mu g/ml, respectively. Trimethoprim-sulfadiazine was active against isolates of A. pleuropneumoniae, S. choleraesuis, S. typhimurium, P. multocida, S. equi, and S. suis (MIC(90)s, less than or.......0 mu g/ml). However, this antimicrobial agent was much less active when it was tested against A. pleuropneumoniae, S. cholerae-suis, and E. coli (MIC(90)s, 16.0, >32.0, and >32.0 mu g/ml, respectively). Against the U.S. isolates of A. pleuropneumoniae and P. multocida, tilmicosin was moderately active...

  2. XML In Vitro Comparison of MIC Crude Extracts of Active Actinomycetes Isolated with Terbinafine, Griseofulvin Ketoconazole and Fluconazole against Microsporum Canis, Microsporum Gypseum and Trichophyton Mentagrophytes

    OpenAIRE

    Keikha, N. (MSc; Ayatollahi Mousavi, SA. (PhD; Nakhaei, AR. (PhD; Amanloo, S. (MSc); Shah idi Benjar, GH. (PhD); Amiri , S . (MSc)

    2015-01-01

    Background and Objective: Dermatophytes are the fungi that have the ability to attack the keratinized tissues such as the skin, hair and nails. Infections caused by these organisms are named dermatophytosis. We aimed to compare Minimum inhibitory concentration (MIC) of Crude extracts of Active Actinomycete Isolates with Terbinafine, Griseofulvin, Ketoconazole and Fluconazole Drugs against Microsporum Canis, Microsporum gypseum and Trichophyton mentagrophytes. Material and Methods: In this exp...

  3. A Cleavable Propeptide Influences Toxoplasma Infection by Facilitating the Trafficking and Secretion of the TgMIC2–M2AP Invasion Complex

    OpenAIRE

    Harper, Jill M.; Huynh, My-Hang; Coppens, Isabelle; Parussini, Fabiola; Moreno, Silvia; Carruthers, Vern B.

    2006-01-01

    Propeptides regulate protein function and trafficking in many eukaryotic systems and have emerged as important features of regulated secretory proteins in parasites of the phylum Apicomplexa. Regulated protein secretion from micronemes and host cell invasion are inextricably linked and essential processes for the apicomplexan parasite Toxoplasma gondii. TgM2AP is a propeptide-containing microneme protein found in a heterohexameric complex with the microneme protein TgMIC2, a protein that has ...

  4. Correlation between Ratio of Serum Doxycycline Concentration to MIC and Rapid Decline of Antibody Levels during Treatment of Q Fever Endocarditis

    OpenAIRE

    Rolain, Jean-Marc; Boulos, Areen; Mallet, Marie-Noëlle; Raoult, Didier

    2005-01-01

    Endocarditis is the major clinical manifestation of chronic Q fever. Although doxycycline along with hydroxychloroquine remains the mainstay of medical therapy for Q fever endocarditis, there are wide variations in the rapidity of the patient's decline of antibody levels during such therapy. We undertook a retrospective examination of whether there was any correlation between the ratio of serum concentration to MIC of doxycycline and response to treatment in patients with Q fever endocarditis...

  5. Flares on dMe stars: IUE and optical observations of At Mic, and comparison of far-ultraviolet stellar and solar flares

    International Nuclear Information System (INIS)

    The paper concerns observations of a large flare event on the dMe star At Mic, detected by the International Ultraviolet Explorer. The far-ultraviolet spectra of the flare is compared with those of other stellar flares, and also with a large solar flare recorded by the Skylab mission in 1973. The quiescent-phase optical and ultraviolet spectrum of the same dMe flare star is discussed. (U.K.)

  6. Minimum inhibitory (MIC) and minimum microbicidal concentration (MMC) of polihexanide and triclosan against antibiotic sensitive and resistant Staphylococcus aureus and Escherichia coli strains

    OpenAIRE

    Assadian, Ojan; Wehse, Katrin; Hübner, Nils-Olaf; Koburger, Torsten; Bagel, Simone; Jethon, Frank; Kramer, Axel

    2011-01-01

    Background: An in-vitro study was conducted investigating the antimicrobial efficacy of polihexanide and triclosan against clinical isolates and reference laboratory strains of Staphylococcus aureus and E scherich ia coli. Methods: The minimal inhibitory concentration (MIC) and the minimal microbicidal concentration (MMC) were determined following DIN 58940-81 using a micro-dilution assay and a quantitative suspension test following EN 1040. Polihexanide was tested in polyethylene glycol 4000...

  7. Minimum inhibitory (MIC and minimum microbicidal concentration (MMC of polihexanide and triclosan against antibiotic sensitive and resistant Staphylococcus aureus and Escherichia coli strains

    Directory of Open Access Journals (Sweden)

    Assadian, Ojan

    2011-01-01

    Full Text Available Background: An in-vitro study was conducted investigating the antimicrobial efficacy of polihexanide and triclosan against clinical isolates and reference laboratory strains of Staphylococcus aureus and Escherichia coli. Methods: The minimal inhibitory concentration (MIC and the minimal microbicidal concentration (MMC were determined following DIN 58940-81 using a micro-dilution assay and a quantitative suspension test following EN 1040. Polihexanide was tested in polyethylene glycol 4000, triclosan in aqueous solutions. Results: Against all tested strains the MIC of polihexanide ranged between 1–2 µg/mL. For triclosan the MICs varied depending on strains ranging between 0.5 µg/mL for the reference strains and 64 µg/mL for two clinical isolates. A logRF >5 without and logRF >3 with 0.2% albumin burden was achieved at 0.6 µg/mL triclosan. One exception was S. aureus strain H-5-24, where a triclosan concentration of 0.6 µg/mL required 1 minute without and 10 minutes with albumin burden to achieve the same logRFs. Polihexanide achieved a logRF >5 without and logRF >3 with albumin burden at a concentration of 0.6 µg/mL within 30 sec. The exception was the North-German epidemic MRSA strain, were an application time of 5 minutes was required. Conclusion: The clinical isolates of E. coli generally showed higher MICs against triclosan, both in the micro-dilution assay as well in the quantitative suspension test than comparable reference laboratory strains. For polihexanide and triclosan strain dependant susceptibility was shown. However, both antimicrobial compounds are effective when used in concentrations common in practice.

  8. Phased array ultrasonic technology (PAUT) contribution to detection and sizing of microbially influenced corrosion (MIC) of service water systems and shutdown coolers heat exchangers in OPG CANDU stations

    International Nuclear Information System (INIS)

    Three PAUT techniques [linear scan - longitudinal waves, sector scan -longitudinal waves and sector scan-transverse waves] were developed and validated to assess the MIC attack in service water systems (SWS) and shutdown coolers heat-exchangers (SDC-HX) of Darlington and Pickering CANDU stations. PAUT employs linear array probes with a frequency between 4-12 MHz, depending on surface conditions, component geometry and MIC size/category to be detected. Examples from lab validation and field trials are presented. Based on field trials results, the techniques were optimized and new cal blocks were manufactured. It was demonstrated for mid-length pipes and for SDC-HX, the PAUT is the best technique compared with D-meter conventional UT and with guided waves. The expected field accuracy is about 0.5 mm (0.020) for large MIC attack. The ligament evaluation is technically achievable for colonies / pin holes located 2 mm under the outer surface. Improvements were identified and implemented for the next outages. (author)

  9. Doppler imaging an X-ray flare on the ultrafast rotator BO Mic - A contemporaneous multiwavelength study using XMM-Newton and VLT

    CERN Document Server

    Wolter, U; Schmitt, J H M M; Ness, J U

    2007-01-01

    We present an analysis of contemporaneous photospheric, chromospheric and coronal structures on the highly active K-dwarf star BO Mic (Speedy Mic). We localize a moderate flare in the stellar atmosphere and study its energetics, size and thermal behaviour. The analysis is based on strictly simultaneous X-ray, UV- and optical observations carried out by XMM-Newton and the VLT. We use Doppler imaging and related methods for the localization of features. Based on X-ray spectroscopy we study the the coronal plasma in and outside the flare. The flare emits in X-rays and UV, but is not detected in white light; it is located at intermediate latitude between an extended spot group and the weakly spotted pole. We estimate its height below 0.4 stellar radii making it clearly distinct in longitude and height from the prominences found about two stellar radii above the surface. While BO Mic's photospheric brightness is modulated due to extended starspots, neither the chromospheric nor the X-ray emission show a pronounced...

  10. Chulos y novios en viñetas. Cómo dedicarse al cómic (gay y no morir en el intento

    Directory of Open Access Journals (Sweden)

    Sebas Martín (autor de cómics

    2009-01-01

    Full Text Available Vivir del cómic es, de por sí, un imposible, pero las dificultades se acrecientan si el objetivo de un autor es dedicarse al cómic gay. En este artículo de cariz autobiográfico, se relatan los obstáculos y los éxitos que han marcado la trayectoria profesional de su autor, desde sus inicios, en los años 80, como creador de un fanzine, hasta la proliferación de proyectos que marcan los 2000. Con todo, se traza un recorrido por el panorama cultural e ideológico de la España de las últimas décadas, a través del cual asistimos a la lenta pero constante superación de los prejuicios que aún hoy rodean tanto el género del cómic como el mundo gay.

  11. Phased array ultrasonic technology (PAUT) contribution to detection and sizing of microbially influenced corrosion (MIC) of service water systems and shutdown coolers heat exchangers in OPG CANDU stations

    Energy Technology Data Exchange (ETDEWEB)

    Ciorau, P.; Pullia, L.; Hazelton, T., E-mail: peter.ciorau@opg.com, E-mail: lou.pullia@opg.com, E-mail: trek.hazelton@opg.com [Ontario Power Generation, Toronto, Ontario (Canada); Daks, W. [CAD WIRE, Markham, Ontario (Canada)

    2008-07-01

    Three PAUT techniques [linear scan - longitudinal waves, sector scan -longitudinal waves and sector scan-transverse waves] were developed and validated to assess the MIC attack in service water systems (SWS) and shutdown coolers heat-exchangers (SDC-HX) of Darlington and Pickering CANDU stations. PAUT employs linear array probes with a frequency between 4-12 MHz, depending on surface conditions, component geometry and MIC size/category to be detected. Examples from lab validation and field trials are presented. Based on field trials results, the techniques were optimized and new cal blocks were manufactured. It was demonstrated for mid-length pipes and for SDC-HX, the PAUT is the best technique compared with D-meter conventional UT and with guided waves. The expected field accuracy is about 0.5 mm (0.020{sup )} for large MIC attack. The ligament evaluation is technically achievable for colonies / pin holes located 2 mm under the outer surface. Improvements were identified and implemented for the next outages. (author)

  12. Anorexia-cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15.

    Science.gov (United States)

    Tsai, V W W; Lin, S; Brown, D A; Salis, A; Breit, S N

    2016-02-01

    Anorexia-cachexia associated with cancer and other diseases is a common and often fatal condition representing a large area of unmet medical need. It occurs most commonly in advanced cancer and is probably a consequence of molecules released by tumour cells, or tumour-associated interstitial or immune cells. These may then act directly on muscle to cause atrophy and/or may cause anorexia, which then leads to loss of both fat and lean mass. Although the aetiological triggers for this syndrome are not well characterized, recent data suggest that MIC-1/GDF15, a transforming growth factor-beta superfamily cytokine produced in large amounts by cancer cells and as a part of other disease processes, may be an important trigger. This cytokine acts on feeding centres in the hypothalamus and brainstem to cause anorexia leading to loss of lean and fat mass and eventually cachexia. In animal studies, the circulating concentrations of MIC-1/GDF15 required to cause this syndrome are similar to those seen in patients with advanced cancer, and at least some epidemiological studies support an association between MIC-1/GDF15 serum levels and measures of nutrition. This article will discuss its mechanisms of central appetite regulation, and the available data linking this action to anorexia-cachexia syndromes that suggest it is a potential target for therapy of cancer anorexia-cachexia and conversely may also be useful for the treatment of severe obesity. PMID:26620888

  13. mics : investigación de conceptos y de términos paleontológicos, y uso como recurso didáctico en la Educación Primaria

    OpenAIRE

    Gonçalves, Rosilene; Machado, Deusana Maria

    2005-01-01

    Este trabajo investiga el modo en que los cómics, como recurso didáctico, tratan los contenidos paleontológicos. Tras un sistemático análisis, resultó evidente que esos conceptos están presentes en los cómics con aciertos pero también con muchos errores y equivocaciones, que no pueden ser ignorados. Los maestros deberían estar atentos a los cómics y usarlos en su práctica educativa.

  14. An investigation of microbial diversity in crude oil & seawater injection systems and microbiologically influenced corrosion (MIC) of linepipe steels under different exposure conditions

    Science.gov (United States)

    AlAbbas, Faisal Mohammed

    During oil and gas operations, pipeline networks are subjected to different corrosion deterioration mechanisms that result from the interaction between the fluid process and the linepipe steel. Among these mechanisms is microbiologically influenced corrosion (MIC) that results from accelerated deterioration caused by different indigenous microorganisms that naturally reside in the hydrocarbon and associated seawater injection systems. The focus of this research is to obtain comprehensive understanding of MIC. This work has explored the most essential elements (identifications, implications and mitigations) required to fully understand MIC. Advanced molecular-based techniques, including sequencing of 16S rRNA genes via 454 pyrosequencing methodologies, were deployed to provide in-depth understanding of the microbial diversity associated with crude oil and seawater injection systems and their relevant impact on MIC. Key microbes including sulfate reducing bacteria (SRB) and iron reducing bacteria (IRB) were cultivated from sour oil well field samples. The microbes' phylotypes were identified in the laboratory to gain more thorough understanding of how they impact microbial corrosion. Electrochemical and advanced surface analytical techniques were used for corrosion evaluations of linepipe carbon steels (API 5L X52 and X80) under different exposure conditions. On the identification front, 454 pyrosequencing of both 16S rRNA genes indicated that the microbial communities in the corrosion products obtained from the sour oil pipeline, sweet crude pipeline and seawater pipeline were dominated by bacteria, though archaeal sequences (predominately Methanobacteriaceae and Methanomicrobiaceae) were also identified in the sweet and sour crude oil samples, respectively. The dominant bacterial phylotypes in the sour crude sample included members of the Thermoanaerobacterales, Synergistales, and Syntrophobacterales. In the sweet crude sample, the dominant phylotypes included

  15. Morphological and sedimentological evidences of repeated avulsions of Someşu Mic River (Romania), associated to salt tectonics

    Science.gov (United States)

    Persoiu, I.; Radoane, M.

    2009-04-01

    Over the last decades, the Holocene evolution of the rivers became an important topic for the scientific community. Whereas most of these studies emphasized the role of climate in the rivers' evolution, little attention has been paid to tectonics, especially at small scale. Here we present a model of Holocene river evolution from the Transylvanian Basin (Romania), where salt tectonics plays an important role. Someşul Mic River (105 km long, 20 mc/s) is located in the NW part of the Transylvanian Basin, Romania. It has a dranage basin of 3773 km2 and the catchment's area is located in the Apuseni Mountains. The river has a well-developed floodplain, with a length of 75 km (calculated along its axis) and an average width of 2 km. In the upper sector, the river flows on red clays, sandstones and limestone of Eocene and Oligocene age (disposed in monoclinal strata), while in the lower sector, the bedrock consists of marls and volcanic tuffs of Miocene age, affected by diapiric alignments. The sedimentary structure of the floodplain is simple, with coarse Lateglacial gravels at the bottom and more fine Holocene sediments (pebble, sand, clay and silt) in its upper part; but some deviations from this general model, attributed to active tectonics, are observed along the river (e.g., absence of the coarser complex, variable proportion of the two complexes, etc). The main characteristic of the river is the high degree of alternation of channel types, from sinuous, meandering and even braided, to anabranched reaches. In order to decipher which mechanism is responsible for the development of the floodplain, we have analyzed in detail a section of the river, using a combination of high-resolution topographic surveys, electrical imaging, core drilling and granulometric analyses. In the investigated area, the river flows on Miocene marls partly covered by sediments, having a sinuous reach, with 2-3 m high banks. To the east, a diapiric syncline stretches parallel to the valley

  16. La selecció de tècniques i cultius pot determinar l’impacte ambiental i econòmic dels horts en terrat

    OpenAIRE

    Sanyé Mengual, Esther

    2016-01-01

    Investigadors del Institut de Ciència i Tecnologia Ambientals (ICTA) de la UAB, en col·laboració amb el Departament de Ciències Agràries de la Universitat de Bolonya, analitzen els impactes ambientals i els costos econòmics de la producció d’aliments en horts comunitaris en terrat des d’una perspectiva quantitativa. Els resultats aporten noves dades i coneixement sobre la contribució a la sostenibilitat de l’agricultura urbana en el marc del disseny urbà. L’estudi identifica les tècniques, el...

  17. Pathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progenies.

    Directory of Open Access Journals (Sweden)

    Murielle Mimeault

    Full Text Available The progression of prostate cancers (PCs to locally invasive, androgen-independent and metastatic disease states is generally associated with treatment resistance and disease relapse. The present study was undertaken to establish the possibility of using a combination of specific oncogenic products, including epidermal growth factor receptor (EGFR, pAkt, nuclear factor-kappaB (NF-κB and macrophage inhibitory cytokine-1 (MIC-1 as biomarkers and therapeutic targets for optimizing the management of patients with localized PC at earlier disease stages. The immunohistochemical and immunofluorescence data have revealed that the expression levels of EGFR, Ser(473-pAkt, NF-κB p65 and MIC-1 proteins were significantly enhanced in the same subset of 76 cases of prostatic adenocarcinoma specimens during the disease progression and these biomarkers were expressed in a small subpopulation of CD133(+ PC cells and the bulk tumor mass of CD133(- PC cells. Importantly, all of these biomarkers were also overexpressed in 80-100% of 30 PC metastasis bone tissue specimens. Moreover, the results have indicated that the EGF-EGFR signaling pathway can provide critical functions for the self-renewal of side population (SP cells endowed with stem cell-like features from highly invasive WPE1-NB26 cells. Of therapeutic interest, the targeting of EGFR, pAkt, NF-κB or MIC-1 was also effective at suppressing the basal and EGF-promoted prostasphere formation by SP WPE1-NB26 cells, inducing disintegration of SP cell-derived prostaspheres and decreasing the viability of SP and non-SP WPE1-NB26 cell fractions. Also, the targeting of these oncogenic products induced the caspase-dependent apoptosis in chemoresistant SP WPE1-NB26 cells and enhanced their sensibility to the cytotoxic effects induced by docetaxel. These findings suggest that the combined use of EGFR, pAkt, NF-κB and/or MIC-1 may represent promising strategies for improving the accuracy of current diagnostic and

  18. DEVELOPMENT OF THE CONCEPT OF THE BIMODAL DISTRIBUTION OF PARTICLES: A PERSONAL HISTORY

    Science.gov (United States)

    The author was hired by EPA in 1971 to head the new Aerosol Research Section (ARS), the first EPA unit devoted to research on atmospheric aerosols. At that time the existing paradigm was that the atmospheric aerosol distribution was monomodal , the mass mean diameter was one mic...

  19. Autoras contemporáneas en la historieta española. Revisión de la etiqueta ‘cómic femenino’

    Directory of Open Access Journals (Sweden)

    Cortijo, Adela

    2011-09-01

    Full Text Available This article, whose title is so generic, does not intend to be an exhaustive and historiographic list of women authoring contemporary Spanish comics. A priori, the deficiencies of the global label “woman comic” are questioned and the representative work of a group of draftswomen and scriptwriters is shown, since the 1980 decade (Madriz, El Cairo and El Víbora to nowadays publications: Laura Pérez-Vernetti, Ana Juan, Ana Miralles, Sonia Pulido and Clara- Tanit. These authors are linked by a generational bond and offer a series of sights, paintstrokes, subjects and diverse plastic styles. The woman production phenomenon is observed along with its reception in ad hoc-collections published by some publishing houses through retrospectives, symposium and exhibitions which are still alerting about the so needed visibility. At the same time, both the atraction and the tendency towards the drawing art and equally the links between comic made by women and the concept related to the author comic, literature and egotistic tales are studied too.

    Este artículo, de título tan genérico, no pretende ser un listado exhaustivo e historiográfico de autoras de historieta contemporánea española. En esta aproximación se cuestionan a priori las deficiencias de la etiqueta global de “cómic femenino”, y se muestra el trabajo representativo de una serie de dibujantes y guionistas mujeres, desde los años ochenta (desde Madriz, El Cairo y El Víbora hasta la actualidad: Laura Pérez-Vernetti, Ana Juan, Ana Miralles, Sonia Pulido y Clara-Tanit. Autoras que se hilvanan en un hilo generacional y que ofrecen una explosión de miradas, de trazos, temas y estilos plásticos distintos. Se observa el fenómeno de la producción femenina y su recepción a través de colecciones ad hoc de algunas casas de edición, de retrospectivas, coloquios y exposiciones, que siguen alertando de la necesidad de una visibilidad

  20. MIC-SVM: Designing A Highly Efficient Support Vector Machine For Advanced Modern Multi-Core and Many-Core Architectures

    Energy Technology Data Exchange (ETDEWEB)

    You, Yang; Song, Shuaiwen; Fu, Haohuan; Marquez, Andres; Mehri Dehanavi, Maryam; Barker, Kevin J.; Cameron, Kirk; Randles, Amanda; Yang, Guangwen

    2014-08-16

    Support Vector Machine (SVM) has been widely used in data-mining and Big Data applications as modern commercial databases start to attach an increasing importance to the analytic capabilities. In recent years, SVM was adapted to the field of High Performance Computing for power/performance prediction, auto-tuning, and runtime scheduling. However, even at the risk of losing prediction accuracy due to insufficient runtime information, researchers can only afford to apply offline model training to avoid significant runtime training overhead. To address the challenges above, we designed and implemented MICSVM, a highly efficient parallel SVM for x86 based multi-core and many core architectures, such as the Intel Ivy Bridge CPUs and Intel Xeon Phi coprocessor (MIC).

  1. Cálcul estructural d'un Observatori Astronómic situat a La Palma (Canàries), segons Normativa ENV 1993-1-1

    OpenAIRE

    Lacroizette i Mañas, Xavier

    2004-01-01

    Premi al millor Projecte de Fi de Carrera presentat durant el curs 2004-2005 en l'àmbit de Construcció que atorga el GREMI DE CONSTRUCTORS D'OBRES El present Projecte de Fi de Carrera està dedicat al disseny i càlcul estructural d’un dels complexes que composen l’Observatori Astronòmic del "Roque de los Muchachos", situat a la illa de la Palma (Canàries). Els diferents càlculs de la estructura metàl·lica s’han realitzat segons la normativa experimental europea ENV 1993-1-1, més coneg...

  2. Hybrid MPI/OpenMP First Principles Materials Science Codes for Intel Xeon Phi (MIC) based HPC: The Petascale and Beyond

    Science.gov (United States)

    Canning, Andrew; Deslippe, Jack; Chelikowsky, James; Louie, Steven G.

    2015-03-01

    Exploiting the full potential of present petascale and future exascale supercomputers based on many core chips requires a high level of threading on the node as well as reduced communications between the nodes to scale to large node counts. We will present results for a variety of first principles materials science codes (Berkeley-GW, PARATEC, PARSEC) on Intel Xeon Phi (MIC) based supercomputers for algorithms using hybrid OpenMP/MPI parallelism to obtain both efficiently threaded single chip performance and parallel scaling to large node counts. Support provided through the SciDAC program funded by U.S. Department of Energy, Office of Science, ASCR and BES under Contract No. DE-AC02-05CH11231 at LBNL and Award No. DESC0008877 at UT, Austin.

  3. Comparison of disc and MIC reduction methods with polymerase chain reaction for the detection of metallo-β-lactamase in Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    S Buchunde

    2012-01-01

    Full Text Available Purpose: The present study was undertaken to evaluate the screening antibiotic, confirmatory phenotypic test and agent against PCR as gold standard and to detect the prevalent MBL gene. Materials and Methods: Three hundred and twenty-six Pseudomonas aeruginosa isolates were screened for resistance to Imipenem (IPM, Meropemem (MEM and Ceftazidime (CAZ by disc diffusion. Isolates resistant to any of these were considered screen test-positive for MBL and were subjected to Double disc synergy test (DDST and Disc potentiation test (DPT: Using IPM, MEM and CAZ alone and with EDTA, Minimum inhibitory concentration (MIC reduction [four-fold or more reduction in MIC of IPM and MEM in presence of chelators: EDTA and 1,10-phenanthroline (EPI/EPM: EDTA-phenanthroline- Imipenem/Meropenem Broth Microdilution method] and polymerase chain reaction (PCR for blaIMP and blaVIM . Results: Screen test-positives by MEM and CAZ were 19.3% as against 17.8% by IPM. MEMDDST, DPT and EPM confirmed 100% screen-test positives as against 93.7% by CAZ DDST and DPT-2, 76.2% by CAZ DPT-1, 88.9% by IPM DDST, 85.7% by IPM DPT-1 and 92.1% by EPI. IPMand CAZ DDST together confirmed 100% while IPM and CAZ DPT-2 confirmed 96.8%. All 63 screen-test positives showed the presence of blaVIM . Conclusions: MEM was found to be the best screening and confirmatory agent for MBL detection and blaVIM was found to be the prevalent MBL gene in this part of the country.

  4. Occupy Wall Street as Immanent Critique: Why IR Theory Needs a ‘Mic Check!’

    Directory of Open Access Journals (Sweden)

    Nicholas J. Kiersey

    2012-03-01

    Full Text Available The recent movements that have emerged across the world to ‘occupy’ various public spaces present an immanent critique of the contemporary arrangements of global politics – one that theorists of International Relations (IR and International Political Economy(IPE should reflect on with some urgency. Emerging from a complex intertext including, but by no means limited to, anarchist and neo-Marxist frameworks, the movement has called for a recognition and appraisal of the ‘communism of everyday life’. Resonating with arguments made in Hardt and Negri’s Commonwealth (2009, as well as David Graeber's Debt: The First 5000 Years (2011, the movements appear to wish to draw attention to a dominant capitalist ontology which denies the highly distributed and social nature of the way in which real value production takes place today. In this context, they argue, the burden of debt that the 99% must endure merely to maintain a dignified standard of living bespeaks the erosion of any semblance of democracy in the allocation of social wealth...

  5. Estudi longitudinal de l'estr??s acad??mic i el malestar psicol??gic associat al llarg dels cinc cursos de Biologia de la Universitat Pompeu Fabra

    OpenAIRE

    Baill??s L??zaro, Eva

    2009-01-01

    L'objectiu de la investigaci?? va ser estudiar l'estr??s acad??mic, les seves fonts, i les conseq????ncies que podien tenir en la salut dels estudiants de biologia de la UPF al llarg dels anys de la carrera, recollint dades d'una mostra representativa d'alumnes. Per avaluar les fonts d'estr??s es va utilitzar el Q??estionari d'Estr??s Acad??mic (QEA). Per mesurar les conseq????ncies de l'estr??s vam usar el "Cuestionario de Salud General" (G.H.Q-28) i el "Q??estionari d'Ansietat Estat-Tret" (...

  6. Telavancin demonstrates activity against methicillin-resistant Staphylococcus aureus isolates with reduced susceptibility to vancomycin, daptomycin, and linezolid in broth microdilution MIC and one-compartment pharmacokinetic/pharmacodynamic models.

    Science.gov (United States)

    Smith, Jordan R; Barber, Katie E; Hallesy, Jessica; Raut, Animesh; Rybak, Michael J

    2015-09-01

    Methicillin-resistant Staphylococcus aureus (MRSA) isolates have arisen with reduced susceptibility to several anti-MRSA agents. Telavancin (TLV), a novel anti-MRSA agent, retains low MICs against these organisms. Our objective was to determine the MICs for TLV, daptomycin (DAP), vancomycin (VAN), and linezolid (LZD) against daptomycin-nonsusceptible (DNS) S. aureus, vancomycin-intermediate S. aureus (VISA), heteroresistant VISA (hVISA), and linezolid-resistant (LZD(r)) S. aureus. We also evaluated these agents against each phenotype in pharmacokinetic/pharmacodynamic (PK/PD) models. Seventy DNS, 100 VISA, 180 hVISA, and 25 LZD(r) MRSA isolates were randomly selected from our library and tested to determine their MICs against TLV, DAP, VAN, and LZD via broth microdilution and a Trek panel. Four isolates were randomly selected for 168-h in vitro models to evaluate treatment with TLV at 10 mg/kg of body weight/day, DAP at 10 mg/kg/day, VAN at 1 g every 12 h (q12h), and LZD at 600 mg q12h. The MIC50/90 for TLV, DAP, VAN, and LZD against 70 DNS S. aureus isolates were 0.06/0.125 μg/ml, 2/4 μg/ml, 1/2 μg/ml, and 2/2 μg/ml, respectively. Against 100 VISA isolates, the MIC50/90 were 0.06/0.125 μg/ml, 1/1 μg/ml, 4/8 μg/ml, and 1/2 μg/ml, respectively. Against 170 hVISA isolates, the MIC50/90 were 0.06/0.125 μg/ml, 0.5/1 μg/ml, 1/2 μg/ml, and 1/2 μg/ml, respectively. Against 25 LZD(r) isolates, the MIC50/90 were 0.03/0.06 μg/ml, 1/1 μg/ml, 2/2 μg/ml, and 8/8 μg/ml, respectively. The TLV MIC was >0.125 μg/ml for 10/365 (2.7%) isolates. In PK/PD models, TLV was universally bactericidal at 168 h and statistically superior to all antibiotics against DNS S. aureus strain R2334. These data further establish the potency of TLV against resistant MRSA. The model data demonstrate in vitro bactericidal activity of TLV against hVISA, VISA, DNS S. aureus, and LZD(r) S. aureus strains. Further clinical research is warranted. PMID:26124162

  7. Determination Of Prevalence Of Methicillin Resistant Staphylococcus Infections Through Measurement Of Mics Of S. Aureus Isolates Imam Hospital (November 2001 To January 2003

    Directory of Open Access Journals (Sweden)

    M. Mohraz

    2003-08-01

    Full Text Available Methicillin resistant staphylococcus aureus (MRSA is a predominantly nosocomial pathogen which its prevalence has increased worldwide over the past three decades."nMaterials and Methods: This is a descriptive cross-sectional study. The following study is designed for determination of prevalence of MRSA infection through measurement of MICs of S. aureus isolates in Imam Khomeini Hospital (a teaching hospital from November 2001 to January 2003. A total number of 402 specimens were isolated and specified as S. aureus by Imam Khomeini microbiology lab. Demographic and clinical data and results of MIC were analysed by Epilnfo 6 software."nResults: During the study, staphylococcus aureus was isolated from 402 patients that 187 (46.5% of isolates were MRSA and 215 (53.5% were MSSA. Of 402 patients, 254 (63.2% were male and 148 (36.8% were female. The difference of the prevalence of MRSA between males and females was not statistically significant (p= 0.09. The difference in mean age in MRSA and MSSA groups was not statistically significant (p= 0.55. In the age group of < 1 month, the prevalence of MRSA infection was significantly higher than other groups (P= 0.01."nConclusion: In this study, the prevalence of MRSA infection was increased, statistically significant in the presence of such factors as sepsis, longer duration of hospitalization, hospital- acquired infection, history of invasive procedure, history of antimicrobials used in the past 3 months and type of administered antimicrobial (s, history of hospitalization in the preceding year, certain underlying diseases, type of admission ward, type of infection, type of specimen and type of administered antimicrobials for treatment. Surprisingly, the prevalence of MRSA infection in IV drug user group was low that was statistically significant (p< 0.0001. In this study, there was no statistically significant difference in outcome between MRSA infected and MSSA infected patients. Based on results of

  8. El problema de las concepciones alternativas en la actualidad (parte III). Utilización didáctica de los errores conceptuales que aparecen en cómics, prensa, novelas y libros de texto

    OpenAIRE

    Carrascosa Alís, Jaime

    2006-01-01

    La existencia de graves errores conceptuales en artículos de prensa, novelas, cómics e incluso libros de texto está relacionada con el origen y persistencia de determinadas ideas alternativas. Cabe plantearse si no podrían utilizarse estos mismos medios para contribuir al tratamiento y el cambio de tales ideas.

  9. Laboratory investigation of the microbiologically influenced corrosion (MIC) resistance of a novel Cu-bearing 2205 duplex stainless steel in the presence of an aerobic marine Pseudomonas aeruginosa biofilm.

    Science.gov (United States)

    Xia, Jin; Yang, Chunguang; Xu, Dake; Sun, Da; Nan, Li; Sun, Ziqing; Li, Qi; Gu, Tingyue; Yang, Ke

    2015-01-01

    The microbiologically influenced corrosion (MIC) resistance of a novel Cu-bearing 2205 duplex stainless steel (2205 Cu-DSS) against an aerobic marine Pseudomonas aeruginosa biofilm was investigated. The electrochemical test results showed that Rp increased and icorr decreased sharply after long-term immersion in the inoculation medium, suggesting that 2205 Cu-DSS possessed excellent MIC resistance to the P. aeruginosa biofilm. Fluorescence microscope images showed that 2205 Cu-DSS possessed a strong antibacterial ability, and its antibacterial efficiency after one and seven days was 7.75% and 96.92%, respectively. The pit morphology comparison after 14 days between 2205 DSS and 2205 Cu-DSS demonstrated that the latter showed a considerably reduced maximum MIC pit depth compared with the former (1.44 μm vs 9.50 μm). The experimental results suggest that inhibition of the biofilm was caused by the copper ions released from the 2205 Cu-DSS, leading to its effective mitigation of MIC by P. aeruginosa. PMID:26194639

  10. Increasing the impact of medical image computing using community-based open-access hackathons: The NA-MIC and 3D Slicer experience.

    Science.gov (United States)

    Kapur, Tina; Pieper, Steve; Fedorov, Andriy; Fillion-Robin, J-C; Halle, Michael; O'Donnell, Lauren; Lasso, Andras; Ungi, Tamas; Pinter, Csaba; Finet, Julien; Pujol, Sonia; Jagadeesan, Jayender; Tokuda, Junichi; Norton, Isaiah; Estepar, Raul San Jose; Gering, David; Aerts, Hugo J W L; Jakab, Marianna; Hata, Nobuhiko; Ibanez, Luiz; Blezek, Daniel; Miller, Jim; Aylward, Stephen; Grimson, W Eric L; Fichtinger, Gabor; Wells, William M; Lorensen, William E; Schroeder, Will; Kikinis, Ron

    2016-10-01

    The National Alliance for Medical Image Computing (NA-MIC) was launched in 2004 with the goal of investigating and developing an open source software infrastructure for the extraction of information and knowledge from medical images using computational methods. Several leading research and engineering groups participated in this effort that was funded by the US National Institutes of Health through a variety of infrastructure grants. This effort transformed 3D Slicer from an internal, Boston-based, academic research software application into a professionally maintained, robust, open source platform with an international leadership and developer and user communities. Critical improvements to the widely used underlying open source libraries and tools-VTK, ITK, CMake, CDash, DCMTK-were an additional consequence of this effort. This project has contributed to close to a thousand peer-reviewed publications and a growing portfolio of US and international funded efforts expanding the use of these tools in new medical computing applications every year. In this editorial, we discuss what we believe are gaps in the way medical image computing is pursued today; how a well-executed research platform can enable discovery, innovation and reproducible science ("Open Science"); and how our quest to build such a software platform has evolved into a productive and rewarding social engineering exercise in building an open-access community with a shared vision. PMID:27498015

  11. Inhibitory effect of a bioactivity-guided fraction from Rheum undulatum on the acid production of Streptococcus mutans biofilms at sub-MIC levels.

    Science.gov (United States)

    Kim, Jeong-Eun; Kim, Hye-Jin; Pandit, Santosh; Chang, Kee-Wan; Jeon, Jae-Gyu

    2011-04-01

    Rheum undulatum root has been used traditionally in Korea for the treatment of dental diseases. The purpose of this study was to separate a fraction from R. undulatum showing anti-acid production activity against Streptococcus mutans biofilms and identify the main components in that fraction. Methanol extract of R. undulatum root and its fractions were prepared. To select a fraction exhibiting anti-acid production activity, suspension glycolytic pH-drop assay was performed. Among the fractions tested, dichloromethane fraction exhibited the strongest activity in a dose-dependent manner. To examine the effect of the selected fraction on the anti-acid production of S. mutans biofilms, 74 h old S. mutans biofilms were used. The selected fraction reduced the initial rate of acid production of S. mutans biofilms at sub-minimum inhibitory concentration (MIC) levels. HPLC qualitative analysis of the selected fraction indicated that the presence of anthraquinone derivatives, such as aloe-emodin, emodin, chrysophanol and physcion, as main components. PMID:21059383

  12. Comparison of antifungal MICs for yeasts obtained using the EUCAST method in a reference laboratory and the Etest in nine different hospital laboratories.

    Science.gov (United States)

    Dannaoui, E; Paugam, A; Develoux, M; Chochillon, C; Matheron, J; Datry, A; Bouges-Michel, C; Bonnal, C; Dromer, F; Bretagne, S

    2010-07-01

    In routine laboratory practice, the determination of MICs of antifungals for yeasts often relies on the Etest, because of a good correlation with reference methods. However, this correlation was established through predesigned studies, rather than prospective testing. The surveillance programme of fungaemia (YEASTS programme), implemented since 2003, facilitated our comparison of the Etest and the EUCAST results, obtained on a routine basis in nine different hospitals and in a reference laboratory, respectively. The analysis included 690 isolates recovered from blood culture (362 Candida albicans, 113 Candida glabrata, 69 Candida parapsilosis, 55 Candida tropicalis, 31 Cryptococcus neoformans, and 60 other yeast species) that were tested for their susceptibility to amphotericin B (n = 655), fluconazole (n = 669), itraconazole (n = 198), voriconazole (n = 588), flucytosine (n = 314), and caspofungin (n = 244). Agreement between the Etest and EUCAST datasets was calculated and categorized on the basis of previously published breakpoints. The level of agreement at ±2 dilutions was 75% for amphotericin B and 90% for flucytosine; for the azoles, it ranged from 71% for itraconazole to 87% for voriconazole. No significant difference was observed among the yeast species, except for Cryptococcus neoformans and flucytosine, with an agreement <40%. Categorical agreement ranged from 60% for itraconazole to 90% for flucytosine. Major and very major discrepancies occurred in <12% and 6%, respectively. The Etest, even when performed on a routine basis, shows a ≥71% agreement with the EUCAST reference method. PMID:19778296

  13. Sub-MICs of Mentha piperita essential oil and menthol inhibits AHL mediated quorum sensing and biofilm of Gram negative bacteria

    Directory of Open Access Journals (Sweden)

    Fohad Mabood Husain

    2015-05-01

    Full Text Available Bacterial quorum sensing (QS is a density dependent communication system that regulates the expression of certain genes including production of virulence factors in many pathogens. Bioactive plant extract/compounds inhibiting QS regulated gene expression may be a potential candidate as antipathogenic drug. In this study anti-QS activity of peppermint (Mentha piperita oil was first tested using the Chromobacterium violaceum CVO26 biosensor. Further, the findings of the present investigation revealed that peppermint oil at sub-MICs strongly interfered with acyl homoserine lactone (AHL regulated virulence factors and biofilm formation in Pseudomonas aeruginosa and Aeromonas hydrophila. The result of molecular docking analysis attributed the quorum sensing inhibitory activity exhibited by peppermint oil to menthol. Assessment of ability of menthol to interfere with quorum sensing systems of various Gram-negative pathogens comprising diverse AHL molecules revealed that it reduced the AHL dependent production of violacein, virulence factors and biofilm formation indicating broad-spectrum anti-QS activity. Using two E. coli biosensors, MG4/pKDT17 and pEAL08-2, we also confirmed that menthol inhibited both the las and pqs quorum sensing systems. Further, findings of the in vivo studies with menthol on nematode model Caenorhabditis elegans showed significantly enhanced survival of the nematode. Our data identified menthol as a novel broad spectrum quorum sensing inhibitor.

  14. Sub-MICs of Mentha piperita essential oil and menthol inhibits AHL mediated quorum sensing and biofilm of Gram-negative bacteria.

    Science.gov (United States)

    Husain, Fohad M; Ahmad, Iqbal; Khan, Mohammad S; Ahmad, Ejaz; Tahseen, Qudisa; Khan, Mohd Shahnawaz; Alshabib, Nasser A

    2015-01-01

    Bacterial quorum sensing (QS) is a density dependent communication system that regulates the expression of certain genes including production of virulence factors in many pathogens. Bioactive plant extract/compounds inhibiting QS regulated gene expression may be a potential candidate as antipathogenic drug. In this study anti-QS activity of peppermint (Mentha piperita) oil was first tested using the Chromobacterium violaceum CVO26 biosensor. Further, the findings of the present investigation revealed that peppermint oil (PMO) at sub-Minimum Inhibitory Concentrations (sub-MICs) strongly interfered with acyl homoserine lactone (AHL) regulated virulence factors and biofilm formation in Pseudomonas aeruginosa and Aeromonas hydrophila. The result of molecular docking analysis attributed the QS inhibitory activity exhibited by PMO to menthol. Assessment of ability of menthol to interfere with QS systems of various Gram-negative pathogens comprising diverse AHL molecules revealed that it reduced the AHL dependent production of violacein, virulence factors, and biofilm formation indicating broad-spectrum anti-QS activity. Using two Escherichia coli biosensors, MG4/pKDT17 and pEAL08-2, we also confirmed that menthol inhibited both the las and pqs QS systems. Further, findings of the in vivo studies with menthol on nematode model Caenorhabditis elegans showed significantly enhanced survival of the nematode. Our data identified menthol as a novel broad spectrum QS inhibitor. PMID:26029178

  15. mic porno gay

    OpenAIRE

    Salvador, Antonio

    2011-01-01

    Si la historieta pornográfica ha sido, durante años, marginada por los eruditos, la pornografía gay ha sufrido una marginación aún mayor de la que, no obstante, va saliendo desde hace algunos años. En las siguientes páginas se ofrece un selección bibliográfica comentada tanto de historietas como de obras teóricas con la intención de orientar a quienes tengan interés en iniciarse en el estudio de dicho tema..

  16. La industria del cómic en España: radiografía de ¿un mito o una realidad?

    Directory of Open Access Journals (Sweden)

    Pons, Álvaro M.

    2011-09-01

    Full Text Available In spite of the importance of figures referred to published titles, or number of copies printed, which help to set publishing strategies and to really know the comic situation in Spain, there are no liable data. We are giving in this article, some enlightening data along with some explanations related to the evolution of the market from 2001 to 2009. The different titles are grouped considering the place they come from (Europe, Asia, United States…, along with their format (album, book, magazine, comic-book…. Using all this information, we can deduce evolution lines, tendencies, futures perspectives in an industry that, despite its precariousness, is facing an increasing number of copies sold and a progressive settlement in the Spanish publishing world.

    A pesar de la importancia que revestiría para establecer estrategias editoriales y para un mejor conocimiento de la situación del cómic en España, no existen cifras fiables sobre títulos publicados y cifras de tiradas. En este artículo se proporcionan algunos datos aclaradores al respecto. Se ofrece una evolución de nuestro mercado desde 2001 a 2009. Se agrupan los diversos títulos por lugar de procedencia (Europa, Asia, Estados Unidos…, así como por formatos (álbum, libro, revista, comic-book…. De todo ello se desprenden líneas evolutivas, tendencias y perspectivas de futuro de una industria que, a pesar de su precariedad, conoce un aumento de las ventas y un progresivo asentamiento en el panorama de la edición española.

  17. Antimicrobial evaluation of new metallic complexes with xylitol active against P. aeruginosa and C. albicans: MIC determination, post-agent effect and Zn-uptake.

    Science.gov (United States)

    Santi, E; Facchin, G; Faccio, R; Barroso, R P; Costa-Filho, A J; Borthagaray, G; Torre, M H

    2016-02-01

    Xylitol (xylH5) is metabolized via the pentose pathway in humans, but it is unsuitable as an energy source for many microorganisms where it produces a xylitol-induced growth inhibition and disturbance in protein synthesis. For this reason, xylitol is used in the prophylaxis of several infections. In the search of better antimicrobial agents, new copper and zinc complexes with xylitol were synthesized and characterized by analytical and spectrosco pic methods: Na2[Cu3(xylH−4)2]·NaCl·4.5H2O (Cu-xyl) and [Zn4(xylH−4)2(H2O)2]·NaCl·3H2O (Zn-xyl). Both copper and zinc complexes presented higher MIC against Pseudomona aeruginosa than the free xylitol while two different behaviors were found against Candida albicans depending on the complex. The growth curves showed that Cu-xyl presented lower activity than the free ligand during all the studied period. In the case of Znxyl the growth curves showed that the inhibition of the microorganism growth in the first stage was equivalent to that of xylitol but in the second stage (after 18 h) Zn-xyl inhibited more. Besides, the PAE (post agent effect)obtained for Zn-xyl and xyl showed that the recovery from the damage of microbial cells had a delay of 14 and 13 h respectively. This behavior could be useful in prophylaxis treatments for infectious diseases where it is important that the antimicrobial effect lasts longer. With the aim to understand the microbiological activities the analysis of the particle size, lipophilicity and Zn uptake was performed. PMID:26619097

  18. Estudi longitudinal de l'estrès acadèmic i el malestar psicològic associat al llarg dels cinc cursos de Biologia de la Universitat Pompeu Fabra

    OpenAIRE

    Baillès Lázaro, Eva

    2009-01-01

    L'objectiu de la investigació va ser estudiar l'estrès acadèmic, les seves fonts, i les conseqüències que podien tenir en la salut dels estudiants de biologia de la UPF al llarg dels anys de la carrera, recollint dades d'una mostra representativa d'alumnes. Per avaluar les fonts d'estrès es va utilitzar el Qüestionari d'Estrès Acadèmic (QEA). Per mesurar les conseqüències de l'estrès vam usar el "Cuestionario de Salud General" (G.H.Q-28) i el "Qüestionari d'Ansietat Estat-Tret" (STAI-E/R). El...

  19. Different condylar displacements between centric relation and maximum intercuspation before and after orthodontic intervention%正畸干预前后 MIC-CR 位髁突位移变化

    Institute of Scientific and Technical Information of China (English)

    韩旭; 邵玉婷; 孙钦凤; 郭泾

    2015-01-01

    Objective To investigate the effects of orthodontic intervention on maximum intercuspation (MIC)-centric relation (CR)condylar displacement of patients with or without temporomandibular disorders (TMD).Methods A total of 31 orthodontic patients aged 16 to 45 years were selected and divided into the TMD group (n =15)and non-TMD group (n =16).Records of MIC and CR of these patients taken before and after orthodontic intervention were compared.Results The two groups had different MIC-CR displacement before and after treatment.There were more changes in the TMD group,and the changes were mostly favorable.The MIC-CR condylar displacement was correlated with the symptom checklist (SCL)score.Conclusion Orthodontic intervention has effect on condylar position of pa-tients,especially for those with TMD.Orthodontists,therefore,need to understand and pay attention to the effect of malocclusion on TMD and limitations of measurement of condylar displacement (MCD)in the diagnosis.%目的:旨在探讨正畸干预对最大牙尖交错位(MIC)-正中关系位(CR)髁突位移量的影响。方法选取16~45岁门诊正畸患者31例,其中非颞下颌关节紊乱病(TMD)组16例(NTMD 组),TMD 组15例,在正畸干预前后分别取 MIC 与 CR 位记录。分析两组患者正畸干预前后正中牙合位与正中关系位的髁突位置差异。结果正畸干预前 TMD 组与 NTMD 组 MIC-CR 之间髁突位移(MCD)量存在差异,正畸干预后两组 MIC-CR 位移量减小,TMD组较为显著,且多为有利变化,TMD 组正畸干预前后 MIC-CR 髁突位移量与 TMD 症状自评量表得分呈相关性。结论正畸干预在一定程度上对错牙合畸形患者的髁突位置产生影响,对于 TMD 患者尤甚。因此,正畸医生要认识并注意到错牙合畸形对 TMD 产生和发展的作用,并正确认识 MCD 在诊断中的局限性。

  20. Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12.

    OpenAIRE

    Chow, R T; Dougherty, T J; Fraimow, H S; Bellin, E Y; Miller, M H

    1988-01-01

    Quinolone antimicrobial agents are known to interact with DNA gyrase, but the mechanism by which bacterial cell death occurs is not fully understood. In order to determine whether there is a correlation between quinolone-induced inhibition of early (i.e., 10 to 15 min) DNA synthesis and potency (MICs and MBCs), we measured the rate of DNA synthesis in log-phase Escherichia coli K-12 by using [3H]thymidine incorporation. Three quinolones (ciprofloxacin, norfloxacin, and difloxacin) were select...

  1. Incorporação ao solo de substrato contendo micélio e conídios de Pochonia chlamydosporia para o manejo de Meloidogyne javanica

    Directory of Open Access Journals (Sweden)

    Rosangela Dallemole-Giaretta

    2014-04-01

    Full Text Available Os clamidósporos são os principais propágulos utilizados como fonte de inóculo de Pochonia chlamydosporia em experimentos envolvendo o biocontrole do nematoide das galhas. O presente trabalho teve por objetivo avaliar o controle de Meloidogyne javanica em tomateiro por meio da aplicação ao solo de grãos de arroz colonizados pelo fungo contendo apenas micélio e conídio, sem a presença de clamidósporos. O isolado de P. chlamydosporia Pc-10 foi cultivado por 15 dias a 26°C em arroz previamente esterilizado em forno microondas. Dois experimentos foram conduzidos simultaneamente em casa de vegetação. No experimento 1, vasos de 2L de capacidade foram preenchidos com mistura solo:areia (1:1, v:v, contendo 3g kg-1 de solo de grãos de arroz colonizados pelo antagonista. No experimento 2, o fungo foi adicionado ao solo de vasos de 0,5L nas doses de 1, 5, 10, 15, 20, 25 ou 30g kg-1 de solo. Em seguida, o substrato de cada vaso foi infestado com 4.000 ovos de M. javanica e, após 15 dias, uma plântula de tomate foi transplantada. No experimento 1, a aplicação do fungo ao solo reduziu o número de galhas e de ovos do nematoide em 40% e 72,83%, respectivamente. No experimento 2, houve redução do número de ovos a partir de doses de 5g kg 1 de solo e no número de galhas, principalmente, nas doses de 25 e 30g kg-1 de solo. Conclui-se que P. chlamydosporia Pc-10 controlou M. javanica em tomateiro, mesmo quando aplicado ao solo na forma de grãos de arroz colonizados e sem a presença de clamidósporos.

  2. 携带兔斯氏艾美耳球虫MIC-5基因减毒鼠伤寒沙门菌活疫苗的安全性、稳定性与免疫原性%Safety, stability and immunogenicity of attenuated Salmonella typhimurium carrying MIC-5 gene of Eimeria stieda

    Institute of Scientific and Technical Information of China (English)

    孟庆玲; 乔军; 才学鹏; 闫鸿斌; 田广孚; 骆学农

    2011-01-01

    对携带兔斯氏艾美耳球虫微线蛋白-5基因(MIC-5)真核表达质粒asd-pBMIC-5-IL-15的减毒鼠伤寒沙门菌X4550(X4550/asd-pBMIC-5-IL-15)进行了安全性、稳定性与免疫原性试验.结果显示,重组菌在109CFU剂量以下对家兔安全;连续培养30代重组菌,重组表达质粒可稳定存在于X4550内,具有良好的遗传稳定性;用重组菌2次免疫动物后,既能诱导机体产生抗兔斯氏艾美耳球虫抗体,也能显著增强淋巴细胞增殖水平,抗球虫指数为164.4.试验表明,减毒沙门菌介导的兔球虫调节型DNA疫苗具有良好的安全性、稳定性和免疫原性.%The security,stability and immunogenicity trials of recombinant Salmonella typhimurium X4550 carrying rabbit's Eimeria stiedai MIC-5 gene expression plasmid asd-pBMIC-5-IL-15 (X4550/asd-pBMIO5-IL-15) was assayed in this study. The results showed that the 109 CFU inoculation dose was safe in the experimental rabbits. The recombinant plasmid existed stably in X4550 after 30 passages, which displayed a good genetic stability. After two immunizations in rabbits, the recombinant Salmonella typhimurium induced the specific antibodies against rabbit Eimeria stiedai and significantly improved the level of lymphocyte proliferation. The anti-coccidia index reached 164. 4. The results indicated that the regulation DNA vaccine mediated by Salmonella had a good security,stability and immunogenicity against rabbit Eimeria stiedai.

  3. L’herbari de l’Institut Botànic de Barcelona com una eina per la conservació dels tàxons endèmics i amenaçats de Catalunya

    Directory of Open Access Journals (Sweden)

    Gavioli, L.

    2012-12-01

    Full Text Available The herbarium of the Botanic Institute of Barcelona (BC is the largest collection of plants of Catalonia and the second of Spain due to its volume, and it is representative of the flora of the western Mediterranean region. It includes, apart from the general collection, other historical collections (from 17th to early 20th century. The main objectives of this study were to evaluate if the endemic and threatened taxa of Catalonia are represented in the herbarium. We also provide chronological and geographical information of herborization intensity, as well as altitudinal, chorological, chronological, phenological and over-collection risk new data. We analyzed the general collection and part of informatized historical herbaria (Cadevall, Hieraciotheca Gallica et Hispanica, Institució Catalana d’Història Natural, Salvador, Societat Botànica Barcelonesa and Trèmols [volumes I-XXI]. Specimens collected from Catalonia have been found to represent 82.24% of the 304 endemic and threatened taxa. The areas with more herborization pressure were Ribes Valley, Montserrat, Port Massif, Cardó Mountains, Montseny and Montsec Mountains. The new chorological data provided expands the distribution of Berberis vulgaris L. subsp. seroi O. Bolòs & Vigo and Stachys maritima Gouan. New altitudinal and phenological data are provided for nine and 40 taxa, respectively.

    El herbario del Instituto Botánico de Barcelona (BC es la colección de plantas más importante de Cataluña y la segunda de España y es representativo de la flora de la región mediterránea occidental. Incluye la colección general y otras colecciones históricas (desde el siglo XVII hasta principios del XX. Los objetivos principales de este trabajo han sido evaluar la representatividad de los táxones endémicos y amenazados de Cataluña en el herbario así como aportar información de tipo cronológico y geográfico de intensidad de recolección y

  4. Measurement of Vertical Temperature Distribution Using a Single Pair of Loudspeaker and Microphone with Acoustic Reflection

    Science.gov (United States)

    Saito, Ikumi; Mizutani, Koichi; Wakatsuki, Naoto; Kawabe, Satoshi

    2009-07-01

    It is important to maintain an adequate indoor temperature for comfortable working conditions, improvement of the rate of production of farm goods grown in greenhouses, and for saving energy. Thus, it is necessary to measure the temperature distribution to realize efficient air-conditioning systems. However, we have to use many conventional instruments to measure the temperature distribution. We proposed a measurement system for vertical temperature distribution using a single pair of loudspeaker (SP) and microphone (MIC), and acoustic reflectors. This system consists of SP, MIC, and multiple acoustic reflectors, and it can be used to determine the temperature distribution from the mean temperature of the area bounded by two reflectors. In experiments, the vertical temperature distribution was measured using five sound probes in a large facility every 20 s for 24 h. From the results of this experiment, it was verified that this system can be used to measure the vertical temperature distribution from the mean temperature of each area bounded by two reflectors. This system could be used to measure the change in the temperature distribution over time. We constructed a simple system to measure the vertical temperature distribution.

  5. Distributed Knight

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Damm, Christian Heide

    2005-01-01

    An extension of Knight (2005) that support distributed synchronous collaboration implemented using type-based publish/subscribe......An extension of Knight (2005) that support distributed synchronous collaboration implemented using type-based publish/subscribe...

  6. L' évaluation du risque géomorphologique dans le bassin hidrographique Suha Mică (droit affluent de la riviere Moldova

    Directory of Open Access Journals (Sweden)

    Francisca Anca CHIRILOAEI

    2010-02-01

    Full Text Available La cartographie des aires qui présentent un risque géomorphologique est devenue une nécessité sociale. Dans le domaine de la recherche des processus concernant le versant et le canal (le lit de la rivière des éléments indicateurs ont été signalés, et qui peuvent conduire à faire l’inventaire des facteurs de risque locaux. Parmi les nombreuses ossibilités de combinaison des facteurs géomorphologiques qui déterminent la susceptibilité au risque d’un territoire, on a considéré comme étant édifiants pour la zone ’étude les suivants : géologie, pente, l’exposition des versants, l’utilisation des terrains. La carte à risque montre le niveau de l’exposition des certaines aires à un grand dangeret implique une évaluation quantitative stricte. Un niveau élevé de prédisposition au risque d’un territoire s’identifie en plan physique par une susceptibilité accrue aux processus géomorphologiques actuels spécifiques. Sur la base de plusieurs éléments cartographiques on a réalisé la carte de l’expansion des aires avec les processus géomorphologiques actuels dominants, et puis, sur la base des paramètres géographiques mentionnés antérieurement (ci-dessus, on a réalisé la carte du sque géomorphologique pour le bassin hydrographique Suha Mică. Notre étude est originale parce que, par la cartographie géomorphologique détailléeui a été réalisée avant la carte à risque, on a eu la possibilité de vérifier sur le terrain quel facteur est plus important pour l’exposition au risque des différentes unités des aires dansa zone étudiée. Par rapport aux autres réalisations de ce type, où la lithologie a un pourcentage maximum, dans notre cas, le facteur déterminant est la pente du versant. Cefait a mené à une réalisation cartographique plus véridique, fait qu’on a pu voir lors de la vérification de la carte à risque géomorphologique, sur la base de la carte de l

  7. Producción orgánica de tomate mediante la aplicación de humus de lombriz y EcoMic® en condiciones de casa de cultivo

    Directory of Open Access Journals (Sweden)

    Reinaldo Cun G.

    2008-01-01

    Full Text Available El trabajo se desarrolló con el objetivo de comparar el efecto de los biofertilizantes EcoMic® y el humus de lombriz, aplicados al tomate (var. HA 3019 cultivado en condiciones protegidas sobre un suelo Ferralítico Rojo compactado. El estudio se realizó en áreas del Centro de Capacitación y Producción (CCP de la Asociación Cubana de Trabajadores Agrícolas y Forestales (ACTAF durante el invierno del 2005. Los tratamientos consistieron en : (T1, aplicar humus de lombriz (2 kg/m2, antes del trasplante y EcoMic® (1 kg/m2 después del transplante; (T2, aplicar humus de lombriz (2 kg/m2 antes del trasplante y la misma dosis a los 10 días después del trasplante. El rendimiento obtenido en el tratamiento T1 fue mayor (8,4 kg/m2 al T2 (5,01 kg/m2 . La mayor cantidad de frutos con mejor calidad se alcanzó en el tratamiento donde se incluyo el EcoMic® (T1. Desde el punto de vista económico el mayor beneficio neto (8 368 pesos y la mayor relación Beneficio/Costo (1,88, se obtuvo en el tratamiento 1 .La aplicación de estos productos indicó que es factible obtener rendimientos aceptables de tomate sin la utilización de fertilizantes químicos, lo que contribuye a la no contaminación del medio ambiente.

  8. La gestió del temps periescolar com a estratègia d’aprenentatge en la millora dels resultats acadèmics en l’educació secundària obligatòria

    OpenAIRE

    Barberá Cebolla, Juan Pedro

    2016-01-01

    Són moltes les variables i els condicionants implicats en l’aprenentatge responsables d’un adequat o inadequat rendiment acadèmic es considera que la gestió del temps d’aprenentatge periescolar es constitueix en sí mateixa en una variable que pot explicar en gran mesura els entrebancs que se li poden presentar a l’alumnat al llarg de la vida d’aprenentatge escolar. Estudiar comporta de forma generalitzada dedicar certa quantitat de temps el que requereix d’una dosi d’habilitats i estratègies ...

  9. Análisis de las construcciones narrativas del espacio y del tiempo en los cómics de los escolares de tercer ciclo de enseñanza primaria

    OpenAIRE

    Segovia Aguilar, Blas

    2009-01-01

    El objeto de estudio de la presente tesis es el análisis de las peculiaridades discursivas de los cómics realizados por el alumnado de tercer ciclo de Enseñanza Primaria, con la intención de comprender los procesos, habilidades y estrategias que los niños de 10 a 12 años utilizan cuando narran con imágenes y palabras. La creación de este tipo de textos supone el dominio, por parte de sus autores, de habilidades relacionadas con la construcción narrativa - el espacio y el tiempo-, con el leng...

  10. 浅谈对微课、慕课、翻转课堂、混合式学习的认识%Brief Talk about the Knowledge of Mic-Class, MOOC, Flipped Class and Mixed Learning

    Institute of Scientific and Technical Information of China (English)

    张维敏

    2016-01-01

    文章针对当前出现的一些主流热门的教学方法,介绍了微课、慕课、翻转课堂、混合式学习的概念,并阐述了它们之间的关系。%The article not only introduces the theories of mic-class, MOOC, flipped class and mixed learning, but also claims their relationship in allusion to the popular teaching methods nowadays.

  11. Distribution center

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Distribution center is a logistics link fulfill physical distribution as its main functionGenerally speaking, it's a large and hiahly automated center destined to receive goods from various plants and suppliers,take orders,fill them efficiently,and deliver goods to customers as quickly as possible.

  12. INFLUENŢA ORAŞELOR CLUJ-NAPOCA ŞI ORADEA ASUPRA STRUCTURII COMUNITĂŢILOR ZOOBENTONICE DIN RÂURILE SOMEŞUL MIC ŞI CRIŞUL REPEDE

    Directory of Open Access Journals (Sweden)

    Tunde Szatmari

    1999-01-01

    Full Text Available The structure and diversity of stream communities represent a biomonitoring pathway of aquatic ecosystems. The macroinvetebrate benthonic groups are important features used in monitoring of the polluted waters. The present study consists in a general presentation of zoobenthonic communities of Somesul Mic and Crisul Repede Rivers and of alterations in their structure due to Cluj-Napoca town and, respectively, Oradea town. Three quantitative samples were collected at two locations on Somesul Mic River (Gilau-upstream to Cluj-Napoca and Apahida-downstream to Cluj-Napoca and two locations on Crisul Repede River (Fughiu-upstream to Oradea and Cheresig-downstream to Oradea, in august and october 1997. Water temperature, the current velocity, oxygen saturation, pH and conductivity were measured in the river. There are considerable differencies in community structure of the four sampling sites. The diversity of macroinvertebrate groups at the locations upstream to urban centers is greater than downstream, both in summer and in autumn. The General Biotic Index exhibits decreasing values along the two stream sectors (Gilau-Apahida and Fughiu-Cheresig which enhance the affirmation that the two urban and industrial centers are the most important sources of rivers’disturbation.

  13. Distributive luck

    OpenAIRE

    Knight, C

    2012-01-01

    This article explores the Rawlsian goal of ensuring that distributions are not influenced by the morally arbitrary. It does so by bringing discussions of distributive justice into contact with the debate over moral luck initiated by Williams and Nagel. Rawls’ own justice as fairness appears to be incompatible with the arbitrariness commitment, as it creates some equalities arbitrarily. A major rival, Dworkin’s version of brute luck egalitarianism, aims to be continuous wi...

  14. Fuel distribution

    Energy Technology Data Exchange (ETDEWEB)

    Tison, R.R.; Baker, N.R.; Blazek, C.F.

    1979-07-01

    Distribution of fuel is considered from a supply point to the secondary conversion sites and ultimate end users. All distribution is intracity with the maximum distance between the supply point and end-use site generally considered to be 15 mi. The fuels discussed are: coal or coal-like solids, methanol, No. 2 fuel oil, No. 6 fuel oil, high-Btu gas, medium-Btu gas, and low-Btu gas. Although the fuel state, i.e., gas, liquid, etc., can have a major impact on the distribution system, the source of these fuels (e.g., naturally-occurring or coal-derived) does not. Single-source, single-termination point and single-source, multi-termination point systems for liquid, gaseous, and solid fuel distribution are considered. Transport modes and the fuels associated with each mode are: by truck - coal, methanol, No. 2 fuel oil, and No. 6 fuel oil; and by pipeline - coal, methane, No. 2 fuel oil, No. 6 oil, high-Btu gas, medium-Btu gas, and low-Btu gas. Data provided for each distribution system include component makeup and initial costs.

  15. Distributed creativity

    DEFF Research Database (Denmark)

    Glaveanu, Vlad Petre

    This book challenges the standard view that creativity comes only from within an individual by arguing that creativity also exists ‘outside’ of the mind or more precisely, that the human mind extends through the means of action into the world. The notion of ‘distributed creativity’ is not commonly...... used within the literature and yet it has the potential to revolutionise the way we think about creativity, from how we define and measure it to what we can practically do to foster and develop creativity. Drawing on cultural psychology, ecological psychology and advances in cognitive science, this...... book offers a basic framework for the study of distributed creativity that considers three main dimensions of creative work: sociality, materiality and temporality. Starting from the premise that creativity is distributed between people, between people and objects and across time, the book reviews...

  16. El comportament informacional en l’elaboració de treballs acadèmics: un estudi longitudinal als alumnes dels ensenyaments de ciències de la salut de la Fundació Universitària del Bages

    OpenAIRE

    Serra i Ferrer, Montserrat

    2015-01-01

    INTRODUCCIÓ I JUSTIFICACIÓ L'aparició d'internet ha canviat la manera com els estudiants cerquen i gestionen la informació a l'hora de realitzar els treballs acadèmics i això ha propiciat la disminució de la qualitat i la pràctica de mals hàbits com el plagi. Per altra banda, amb l'entrada a l'EEES, hi ha un a sèrie d'aspectes de la competència informacional que cal assolir al llarg dels estudis i que han de proporcionar als alumnes les eines perquè puguin trobar, interpretar i finalment ...

  17. Dret internacional dels drets humans en períodes de crisi: criteris d"aplicació de les obligacions jurídiques internacionals en matèria de drets econòmics, socials i culturals

    OpenAIRE

    Bonet Pérez, Jordi

    2013-01-01

    L"objecte de l"article és oferir una panoràmica dels criteris d"aplicació de les obligacions jurídiques internacionals en matèria de drets econòmics, socials i culturals (DESC) en períodes de crisi. L"estudi analitza les dificultats per considerar una crisi econòmica com una situació excepcional que amenaci la vida de la nació i permeti derogar o suspendre certs drets humans; també clarificar en quina mesura és possible derogar o suspendre els DESC. La pràctica internacional, judicial i quasi...

  18. Spatial distribution

    DEFF Research Database (Denmark)

    Borregaard, Michael Krabbe; Hendrichsen, Ditte Katrine; Nachman, Gøsta Støger

    2008-01-01

    , depending on the nature of intraspecific interactions between them: while the individuals of some species repel each other and partition the available area, others form groups of varying size, determined by the fitness of each group member. The spatial distribution pattern of individuals again strongly...

  19. Quasihomogeneous distributions

    CERN Document Server

    von Grudzinski, O

    1991-01-01

    This is a systematic exposition of the basics of the theory of quasihomogeneous (in particular, homogeneous) functions and distributions (generalized functions). A major theme is the method of taking quasihomogeneous averages. It serves as the central tool for the study of the solvability of quasihomogeneous multiplication equations and of quasihomogeneous partial differential equations with constant coefficients. Necessary and sufficient conditions for solvability are given. Several examples are treated in detail, among them the heat and the Schrödinger equation. The final chapter is devoted to quasihomogeneous wave front sets and their application to the description of singularities of quasihomogeneous distributions, in particular to quasihomogeneous fundamental solutions of the heat and of the Schrödinger equation.

  20. Distribution switchgear

    CERN Document Server

    Stewart, Stan

    2004-01-01

    Switchgear plays a fundamental role within the power supply industry. It is required to isolate faulty equipment, divide large networks into sections for repair purposes, reconfigure networks in order to restore power supplies and control other equipment.This book begins with the general principles of the Switchgear function and leads on to discuss topics such as interruption techniques, fault level calculations, switching transients and electrical insulation; making this an invaluable reference source. Solutions to practical problems associated with Distribution Switchgear are also included.

  1. Damage Distributions

    DEFF Research Database (Denmark)

    Lützen, Marie

    2001-01-01

    The purpose of Task 2.2 of the HARDER project is according to the work package description: For various structural configurations of the struck ship and using the results of Task 2.1, the probability distributions for the damage location and size will be derived. The format will be similar to the...... damage statistics and bow height statistics for vessels in the world fleet. The proposals for the p-, r-, and v-factors have been compared to factors from current regulation by examples.......The purpose of Task 2.2 of the HARDER project is according to the work package description: For various structural configurations of the struck ship and using the results of Task 2.1, the probability distributions for the damage location and size will be derived. The format will be similar to the p...... between the damage location, the damage sizes and the main particulars of the struck vessel. From the numerical simulation and the analyse of the damage statistics it is found that the current formulation from the IMO SLF 43/3/2 can be used as basis for determination of the p-, r-, and v...

  2. Indução de resistência em feijoeiro a mancha angular por extratos de micélio de Pycnoporus sanguineus Resistance induction in bean plants against angular leaf spot by extracts from Pycnoporus sanguineus mycelium

    Directory of Open Access Journals (Sweden)

    Clair Aparecida Viecelli

    2010-03-01

    Full Text Available O feijoeiro (Phaseolus vulgaris L. está entre as principais culturas da agricultura nacional e pode ser afetada por várias doenças, como a mancha angular causada por Pseudocercospora griseola. Com o objetivo de desenvolver métodos alternativos ao químico para o controle desta doença, verificou-se o potencial de extratos de micélio de Pycnoporus sanguineus para atividade antimicrobiana in vitro contra P. griseola e para indução de resistência e ativação de enzimas de defesa em feijoeiro, como peroxidase, polifenoloxidase e β-1,3-glucanase, além de sua influência nos teores de proteínas e clorofilas. Os experimentos in vitro e em casa de vegetação foram constituídos pelos extratos de micélio de P. sanguineus e dos controles água, acibenzolar-S-metil (ASM: 75 mg i.a./L e fungicida azoxystrobin (40 mg i.a./L. In vitro o extrato de micélio apresentou efeito sobre o crescimento micelial, a esporulação e a germinação de esporos de P. griseola. In vivo a severidade foi reduzida em 93% e 50% em casa de vegetação e a campo respectivamente, em relação ao controle água. A atividade das enzimas peroxidase e polifenoloxidase e os teores de proteínas e clorofilas foram maiores nas plantas tratadas com o extrato. Estes resultados indicam a eficiência de P. sanguineus para o controle alternativo da mancha angular do feijoeiro.Angular leaf spot, caused by the fungus Pseudocercospora griseola, is a major disease of common bean (Phaseolus vulgaris L. in Brazil. The objective of this research was to develop an alternative method for controlling this disease based on an aqueous extract of Pycnoporus sanguineus mycelium. It was evaluated the antimicrobial activity of the aqueous extract against P. griseola as well as its activity of resistance induction against angular leaf spot. The role of the plant defense enzymes peroxidase, polyphenol oxidase and β-1,3-glucanase, and the proteins and chlorophyll content was investigated. The

  3. Produção de micélio externo por fungos micorrízicos arbusculares e crescimento da soja em função de doses de fósforo

    Directory of Open Access Journals (Sweden)

    M. A. Nogueira

    2000-06-01

    Full Text Available Em uma associação entre duas espécies de fungos micorrízicos arbusculares (FMAs (Glomus intraradices ou Gigaspora margarita e soja (Glycine max L. Merrill cv. IAC-8, avaliaram-se a produção de massa de material seco da parte aérea (MSPA, a massa de material seco de vagens (MSV, a colonização radicular, a concentração de N, P, K, Ca, Mg, S, Cu, Fe, Mn e Zn na parte aérea e vagens, além das estimativas do comprimento de micélio externo ativo (MEA e micélio externo total (MET. As plantas receberam cinco doses de fósforo (0, 25, 50, 100 e 200 mg kg-1 e as avaliações foram feitas em quatro épocas (15, 30, 60 e 90 dias. A inoculação da soja com G. margarita resultou em redução transitória de crescimento aos 60 dias, enquanto aumentos na MSPA devidos à inoculação com os FMAs foram mais evidentes aos 90 dias. A colonização radicular, a produção de MEA e de MET apresentaram relação negativa com o incremento das doses de P nos tratamentos com FMAs. A menor produção de MEA e a fase de crescimento lento mais prolongada observadas no tratamento com G. margarita podem ter colaborado para a redução do crescimento das plantas aos 60 dias. O comprimento de MEA produzido por G. intraradices aumentou com o tempo e diminuiu com o aumento das doses de P. Esses efeitos foram menos evidentes para G. margarita. As concentrações de Fe e Mn nas vagens aos 90 dias foram menores nos tratamentos inoculados com FMAs nas menores doses de P, nas quais foi observada maior colonização radicular.

  4. Why MIC matters? Microbiologists vs. clinicians

    Directory of Open Access Journals (Sweden)

    Corrado Girmenia

    2013-07-01

    Full Text Available Several mechanisms of resistance may interfere with the patients’ healing from a fungal infection. However, in premature children fungi are generally susceptible to antifungal agents, except in case of vertical transmission from the mother. In vitro sensitivity tests have been recently harmonized between American and European standards, after years of unhomogeneity: to date, the interpretation of epidemiological cut-off of wild-type population and clinical cut-off are common, and are often updated. Sensitivity tests are difficult to perform, but luckily new commercial tests approvedby FDA are available. Sometimes, knowing the intrinsic sensitivities and resistances of every fungal species and subspecies may be enough in the clinical practice, since few resistances are acquired.http://dx.doi.org/rhc.v4i1S.863

  5. Computational algorithms for vesicle electrohydrodyna- mics

    Science.gov (United States)

    Veerapaneni, Shravan

    2015-11-01

    In this talk, we discuss a new integral equation method for simulating the electrohydrodynamics of a suspension of vesicles. The classical Taylor-Melcher leaky-dielectric model is employed for the electric response of each vesicle and the Helfrich energy model combined with local inextensibility is employed for its elastic response. The coupled governing equations for the vesicle position and its transmembrane electric potential are solved using a numerical method that is spectrally accurate in space and first-order in time. The method uses a semi-implicit time-stepping scheme to overcome the numerical stiffness associated with the governing equations. We will present new results on the suspension rheology, two-body interactions and pattern formation. This is joint work with Bowei Wu. This work was sponsored by NSF under grants DMS-1224656 and DMS-1418964.

  6. EIS Response of MIC on Carbon Steel

    DEFF Research Database (Denmark)

    Hilbert, Lisbeth Rischel; Maahn, Ernst

    1998-01-01

    Abstract Microbially influenced corrosion of carbon steel under sulphate reducing (sulphide-producing) bacterial activity (SRB) results in the formation of both ferrous sulphides as well as biofilm on the metal surface. The electrochemical characteristics of the ferrous sulphide/steel interface as...... identifying the formation of biofilm/ferrous sulphide layers but unfortunately also that corrosion rate estimation by these electrochemical techniques is unreliable when these layers form. These considerations are also relevant for other corrosion systems where film formation might mask the electrochemical...

  7. Cambio de rumbo. Interacción comercial entre el Bronce Final atlántico ibérico y micénico en el Mediterráneo Central (1425-1050 a.C.

    Directory of Open Access Journals (Sweden)

    Mederos Martín, Alfredo

    1997-12-01

    Full Text Available The aim of this work is to present a new interpretation on the commercial exchanges during the Late Bronze Age IC-IIC, c. 1425-I050 BC, between the Western and Central Mediterranean, starting from a review of two types of metallic artefact, axes and swords, originating from the Iberian Peninsula, and present in Sardinia, Sicily and Lazio in the Italian Peninsula. We start from three premises: the calibrated chronology of the Late Bronze Age in the Iberian Peninsula, Sardinia and Sicily-Eolian. Secondly, a more accurate chronology of the Iberian artefacts present in Italian settlements and deposits. And finally, the analysis of the confluence between the Atlantic and Mycenaean trade in the Central Mediterranean, particularly during the Late Bronze Age IC-IIA/Late Helladic IIIA-IIIB, c. 1425-1225 BC, to reveal that the mycenaean pottery presence in Andalusia can not be tried as an isolated phenomenon, but is integrated within the commercial interrelationship that existed between the Western and Eastern Mediterranean around the islands of Sardinia and Sicily in the Central Mediterranean.

    El objetivo de este trabajo es ofrecer una nueva interpretación sobre los intercambios comerciales durante el Bronce Final IC-IIC, ca. 1425-1050 AC, entre el Mediterráneo Occidental y Central, a partir de una revisión de dos tipos de artefactos metálicos, hachas y espadas, procedentes de la Península Ibérica, y presentes en Cerdeña, Sicilia y el Lazio en la Península Italiana. Se parte de tres premisas; la primera, la cronología calibrada del Bronce Final en la Península Ibérica, Cerdeña y Sicilia-Eolias. En segundo lugar, un encuadre temporal más preciso de los artefactos ibéricos presentes en los yacimientos y depósitos italianos. Y finalmente, el análisis de la confluencia del comercio atlántico y micénico en el Mediterráneo Central, particularmente durante el Bronce Final IC-IIA/ Heládico Final IIIA-IIIB, ca. 1425

  8. Product Distributions for Distributed Optimization. Chapter 1

    Science.gov (United States)

    Bieniawski, Stefan R.; Wolpert, David H.

    2004-01-01

    With connections to bounded rational game theory, information theory and statistical mechanics, Product Distribution (PD) theory provides a new framework for performing distributed optimization. Furthermore, PD theory extends and formalizes Collective Intelligence, thus connecting distributed optimization to distributed Reinforcement Learning (FU). This paper provides an overview of PD theory and details an algorithm for performing optimization derived from it. The approach is demonstrated on two unconstrained optimization problems, one with discrete variables and one with continuous variables. To highlight the connections between PD theory and distributed FU, the results are compared with those obtained using distributed reinforcement learning inspired optimization approaches. The inter-relationship of the techniques is discussed.

  9. Distributed Computing: An Overview

    Directory of Open Access Journals (Sweden)

    Md. Firoj Ali

    2015-07-01

    Full Text Available Decrease in hardware costs and advances in computer networking technologies have led to increased interest in the use of large-scale parallel and distributed computing systems. Distributed computing systems offer the potential for improved performance and resource sharing. In this paper we have made an overview on distributed computing. In this paper we studied the difference between parallel and distributed computing, terminologies used in distributed computing, task allocation in distributed computing and performance parameters in distributed computing system, parallel distributed algorithm models, and advantages of distributed computing and scope of distributed computing.

  10. Protection of Distribution Systems with Distributed Generation

    OpenAIRE

    Vassbotten, Kristian

    2015-01-01

    In recent years the amount of distributed generation(DG) in distribution systems have increased. This poses problems for the traditional protection scheme, with non-directional over-current relays and fuses. When DG is introduced the load flow in distribution systems are often reversed; there is a surplus of power on the radial. Present thesis seeks to determine the most beneficial protection scheme to use in distribution systems with DG. To investigate the impact of different relays and...

  11. Bivariate discrete Linnik distribution

    Directory of Open Access Journals (Sweden)

    Davis Antony Mundassery

    2014-10-01

    Full Text Available Christoph and Schreiber (1998a studied the discrete analogue of positive Linnik distribution and obtained its characterizations using survival function. In this paper, we introduce a bivariate form of the discrete Linnik distribution and study its distributional properties. Characterizations of the bivariate distribution are obtained using compounding schemes. Autoregressive processes are developed with marginals follow the bivariate discrete Linnik distribution.

  12. Bivariate discrete Linnik distribution

    OpenAIRE

    Davis Antony Mundassery; Jayakumar, K.

    2014-01-01

    Christoph and Schreiber (1998a) studied the discrete analogue of positive Linnik distribution and obtained its characterizations using survival function. In this paper, we introduce a bivariate form of the discrete Linnik distribution and study its distributional properties. Characterizations of the bivariate distribution are obtained using compounding schemes. Autoregressive processes are developed with marginals follow the bivariate discrete Linnik distribution.

  13. On bivariate geometric distribution

    OpenAIRE

    Jayakumar, K.; Davis Antony Mundassery

    2013-01-01

    Characterizations of bivariate geometric distribution using univariate and bivariate geometric compounding are obtained. Autoregressive models with marginals as bivariate geometric distribution are developed. Various bivariate geometric distributions analogous to important bivariate exponential distributions like, Marshall-Olkin’s bivariate exponential, Downton’s bivariate exponential and Hawkes’ bivariate exponential are presented.

  14. The Amoroso Distribution

    CERN Document Server

    Crooks, Gavin E

    2010-01-01

    Herein, we review the properties of the Amoroso distribution, the natural unification of the gamma and extreme value distribution families. Over 50 distinct, named distributions (and twice as many synonyms) occur as special cases or limiting forms. Consequently, this single simple functional form encapsulates and systematizes an extensive menagerie of interesting and common probability distributions.

  15. Extended Poisson Exponential Distribution

    Directory of Open Access Journals (Sweden)

    Anum Fatima

    2015-09-01

    Full Text Available A new mixture of Modified Exponential (ME and Poisson distribution has been introduced in this paper. Taking the Maximum of Modified Exponential random variable when the sample size follows a zero truncated Poisson distribution we have derived the new distribution, named as Extended Poisson Exponential distribution. This distribution possesses increasing and decreasing failure rates. The Poisson-Exponential, Modified Exponential and Exponential distributions are special cases of this distribution. We have also investigated some mathematical properties of the distribution along with Information entropies and Order statistics of the distribution. The estimation of parameters has been obtained using the Maximum Likelihood Estimation procedure. Finally we have illustrated a real data application of our distribution.

  16. STIS MAMA Fold Distribution

    Science.gov (United States)

    Wheeler, Thomas

    2013-10-01

    The performance of MAMA microchannel plates can be monitored using a MAMA fold distribution procedure. The fold distribution provides a measurement of the distribution of charge cloud sizes incident upon the anode giving some measure of change in the pulse-height distribution of the MCP and, therefore, MCP gain. This proposal executes the same steps as the STIS MAMA Fold Distribution, Proposal 13149, as Cycle 20.

  17. Greening File Distribution: Centralized or Distributed?

    CERN Document Server

    Verma, Kshitiz; Anta, Antonio Fernández; Rumín, Rubén Cuevas; Azcorra, Arturo

    2011-01-01

    Despite file-distribution applications are responsible for a major portion of the current Internet traffic, so far little effort has been dedicated to study file distribution from the point of view of energy efficiency. In this paper, we present a first approach at the problem of energy efficiency for file distribution. Specifically, we first demonstrate that the general problem of minimizing energy consumption in file distribution in heterogeneous settings is NP-hard. For homogeneous settings, we derive tight lower bounds on energy consumption, and we design a family of algorithms that achieve these bounds. Our results prove that collaborative p2p schemes achieve up to 50% energy savings with respect to the best available centralized file distribution scheme. Through simulation, we demonstrate that in more realistic cases (e.g., considering network congestion, and link variability across hosts) we validate this observation, since our collaborative algorithms always achieve significant energy savings with res...

  18. Distributed Data Management and Distributed File Systems

    Science.gov (United States)

    Girone, Maria

    2015-12-01

    The LHC program has been successful in part due to the globally distributed computing resources used for collecting, serving, processing, and analyzing the large LHC datasets. The introduction of distributed computing early in the LHC program spawned the development of new technologies and techniques to synchronize information and data between physically separated computing centers. Two of the most challenges services are the distributed file systems and the distributed data management systems. In this paper I will discuss how we have evolved from local site services to more globally independent services in the areas of distributed file systems and data management and how these capabilities may continue to evolve into the future. I will address the design choices, the motivations, and the future evolution of the computing systems used for High Energy Physics.

  19. Distributed Data Management and Distributed File Systems

    CERN Document Server

    Girone, Maria

    2015-01-01

    The LHC program has been successful in part due to the globally distributed computing resources used for collecting, serving, processing, and analyzing the large LHC datasets. The introduction of distributed computing early in the LHC program spawned the development of new technologies and techniques to synchronize information and data between physically separated computing centers. Two of the most challenges services are the distributed file systems and the distributed data management systems. In this paper I will discuss how we have evolved from local site services to more globally independent services in the areas of distributed file systems and data management and how these capabilities may continue to evolve into the future. I will address the design choices, the motivations, and the future evolution of the computing systems used for High Energy Physics.

  20. Sobrevivência de micélio e escleródios de Rhizoctonia solani tratados com Trichoderma spp., em restos de cultura de Eucalyptus sp. Survival of Rhizoctonia solani mycelia and sclerotia treated with Trichoderma spp., in Eucalyp]tus sp. litter

    OpenAIRE

    Sandra Kunieda-Alonso; Acelino C. Alfenas; Luiz A. Maffia

    2005-01-01

    Este trabalho objetivou estudar a sobrevivência de micélio e escleródios de Rhizoctonia solani AG1-1C, em restos de cultura de eucalipto (Eucalyptus spp.) e avaliar a eficiência dos isolados Trichoderma longibrachiatum (UFV-1) e T. inhamatum (UFV-2 e UFV-3), comprovadamente antagônicos a R. solani, em reduzir a sobrevivência do patógeno, em condições de campo. Ao longo de 12 meses de avaliação, a sobrevivência de R. solani em folhas de eucalipto infetadas não foi afetada por fatores ambientes...

  1. Distributed Verification and Hardness of Distributed Approximation

    CERN Document Server

    Sarma, Atish Das; Kor, Liah; Korman, Amos; Nanongkai, Danupon; Pandurangan, Gopal; Peleg, David; Wattenhofer, Roger

    2010-01-01

    We study the {\\em verification} problem in distributed networks, stated as follows. Let $H$ be a subgraph of a network $G$ where each vertex of $G$ knows which edges incident on it are in $H$. We would like to verify whether $H$ has some properties, e.g., if it is a tree or if it is connected. We would like to perform this verification in a decentralized fashion via a distributed algorithm. The time complexity of verification is measured as the number of rounds of distributed communication. In this paper we initiate a systematic study of distributed verification, and give almost tight lower bounds on the running time of distributed verification algorithms for many fundamental problems such as connectivity, spanning connected subgraph, and $s-t$ cut verification. We then show applications of these results in deriving strong unconditional time lower bounds on the {\\em hardness of distributed approximation} for many classical optimization problems including minimum spanning tree, shortest paths, and minimum cut....

  2. Factorisations of distributive laws

    OpenAIRE

    Kraehmer, Ulrich; Slevin, Paul

    2014-01-01

    Recently, Boehm and Stefan constructed duplicial (paracyclic) objects from distributive laws between (co)monads. Here we define the category of factorisations of a distributive law, show that it acts on this construction, and give some explicit examples.

  3. Ticks: Geographic Distribution

    Science.gov (United States)

    ... abroad Borrelia miyamotoi Borrelia mayonii Geographic distribution of ticks that bite humans Recommend on Facebook Tweet Share ... and may be difficult to identify. American dog tick ( Dermacentor variabilis ) Where found: Widely distributed east of ...

  4. Hyperfinite Representation of Distributions

    Indian Academy of Sciences (India)

    J Sousa Pinto; R F Hoskins

    2000-11-01

    Hyperfinite representation of distributions is studied following the method introduced by Kinoshita [2, 3], although we use a different approach much in the vein of [4]. Products and Fourier transforms of representatives of distributions are also analysed.

  5. Asymmetric Parton Distributions

    CERN Document Server

    Radyushkin, A V

    1997-01-01

    Applications of perturbative QCD to hard exclusive electroproduction processes in the Bjorken limit at small invariant momentum transfer t bring in a new type of parton distributions which have hybrid properties, resembling both the parton distribution functions and the distribution amplitudes. Their t-dependence is analogous to that of hadronic form factors. We discuss general properties of these new parton distributions, their relation to usual parton densities and the evolution equations which they satisfy.

  6. Ambiguous Proximity Distribution

    OpenAIRE

    Wang, Quanquan; Li, Yongping

    2014-01-01

    Proximity Distribution Kernel is an effective method for bag-of-featues based image representation. In this paper, we investigate the soft assignment of visual words to image features for proximity distribution. Visual word contribution function is proposed to model ambiguous proximity distributions. Three ambiguous proximity distributions is developed by three ambiguous contribution functions. The experiments are conducted on both classification and retrieval of medical image data sets. The ...

  7. Distributed Robotics Education

    OpenAIRE

    LUND, Henrik Hautop; Pagliarini, Luigi

    2011-01-01

    Distributed robotics takes many forms, for instance, multirobots, modular robots, and self-reconfigurable robots. The understanding and development of such advanced robotic systems demand extensive knowledge in engineering and computer science. In this paper, we describe the concept of a distributed educational system as a valuable tool for introducing students to interactive parallel and distributed processing programming as the foundation for distributed robotics and human-robot interaction...

  8. Leadership for Distributed Teams

    NARCIS (Netherlands)

    De Rooij, J.P.G.

    2009-01-01

    The aim of this dissertation was to study the little examined, yet important issue of leadership for distributed teams. Distributed teams are defined as: “teams of which members are geographically distributed and are therefore working predominantly via mediated communication means on an interdepende

  9. Reproduction and Distribution.

    Science.gov (United States)

    Greer, Michael

    1989-01-01

    This latest in a series of articles on the manager's role in an instructional design project highlights techniques for managing the reproduction and distribution of materials. Guidelines for orienting staff are suggested, a sample reproduction and distribution schedule is given, and a storage and distribution system is discussed. (LRW)

  10. Verification of LHS distributions.

    Energy Technology Data Exchange (ETDEWEB)

    Swiler, Laura Painton

    2006-04-01

    This document provides verification test results for normal, lognormal, and uniform distributions that are used in Sandia's Latin Hypercube Sampling (LHS) software. The purpose of this testing is to verify that the sample values being generated in LHS are distributed according to the desired distribution types. The testing of distribution correctness is done by examining summary statistics, graphical comparisons using quantile-quantile plots, and format statistical tests such as the Chisquare test, the Kolmogorov-Smirnov test, and the Anderson-Darling test. The overall results from the testing indicate that the generation of normal, lognormal, and uniform distributions in LHS is acceptable.

  11. DISTRIBUTED QUERY OPTIMIZATION

    Directory of Open Access Journals (Sweden)

    Nicoleta IACOB

    2010-12-01

    Full Text Available The need for the distributed systems has been determined by the type of business developed by companies with offices geographically distributed where the specific organizational structure promotes a decentralized business model. This paper describes the techniques and concepts of system architecture for distributed database management systems, followed by the presentation of implementation phases involved when dealing with the distributed queries across distributed systems. The goal of query optimization is to determine the most efficient way to execute a query in a distributed environment, by obtaining a lower system response time and also by minimizing the query execution time. For this, we will analyze the factors that influence the ways to execute a query and we will also review the available strategies to optimize the distributed query execution.

  12. Bivariate extreme value distributions

    Science.gov (United States)

    Elshamy, M.

    1992-01-01

    In certain engineering applications, such as those occurring in the analyses of ascent structural loads for the Space Transportation System (STS), some of the load variables have a lower bound of zero. Thus, the need for practical models of bivariate extreme value probability distribution functions with lower limits was identified. We discuss the Gumbel models and present practical forms of bivariate extreme probability distributions of Weibull and Frechet types with two parameters. Bivariate extreme value probability distribution functions can be expressed in terms of the marginal extremel distributions and a 'dependence' function subject to certain analytical conditions. Properties of such bivariate extreme distributions, sums and differences of paired extremals, as well as the corresponding forms of conditional distributions, are discussed. Practical estimation techniques are also given.

  13. Predictable return distributions

    DEFF Research Database (Denmark)

    Pedersen, Thomas Quistgaard

    This paper provides detailed insights into predictability of the entire stock and bond return distribution through the use of quantile regression. This allows us to examine speci…c parts of the return distribution such as the tails or the center, and for a suf…ciently …ne grid of quantiles we can...... predictable as a function of economic state variables. The results are, however, very different for stocks and bonds. The state variables primarily predict only location shifts in the stock return distribution, while they also predict changes in higher-order moments in the bond return distribution. Out......-of-sample analyses show that the relative accuracy of the state variables in predicting future returns varies across the distribution. A portfolio study shows that an investor with power utility can obtain economic gains by applying the empirical return distribution in portfolio decisions instead of imposing an...

  14. Kernel Oriented Generator Distribution

    OpenAIRE

    Bekker, A.; Arashi, M.

    2014-01-01

    Matrix variate beta (MVB) distributions are used in different fields of hypothesis testing, multivariate correlation analysis, zero regression, canonical correlation analysis and etc. In this approach a unified methodology is proposed to generate matrix variate distributions by combining the kernel of MVB distributions of different types with an unknown Borel measurable function of trace operator over matrix space, called generator component. The latter component is a principal element of the...

  15. Managing Distributed Software Projects

    OpenAIRE

    Persson, John Stouby

    2010-01-01

    Increasingly, software projects are becoming geographically distributed, with limited face-toface interaction between participants. These projects face particular challenges that need careful managerial attention. This PhD study reports on how we can understand and support the management of distributed software projects, based on a literature study and a case study. The main emphasis of the literature study was on how to support the management of distributed software projects, but also contri...

  16. Leadership for Distributed Teams

    OpenAIRE

    De Rooij, J.P.G.

    2009-01-01

    The aim of this dissertation was to study the little examined, yet important issue of leadership for distributed teams. Distributed teams are defined as: “teams of which members are geographically distributed and are therefore working predominantly via mediated communication means on an interdependent task and in realizing a joint goal” (adapted from Bell & Kozlowski, 2002 and Dubé & Paré, 2004). Chapter 1 first presents the outline of the dissertation. Next, several characteristics of distri...

  17. Energy of generalized distributions

    OpenAIRE

    González-Dávila, J.C.

    2015-01-01

    We consider the energy of smooth generalized distributions and also of singular foliations on compact Riemannian manifolds for which the set of their singularities consists of a finite number of isolated points and of pairwise disjoint closed submanifolds. We derive a lower bound for the energy of all $q$-dimensional almost regular distributions, for each $q< \\dim M,$ and find several examples of foliations which minimize the energy functional over certain sets of smooth generalized distribut...

  18. Distributed generation systems model

    Energy Technology Data Exchange (ETDEWEB)

    Barklund, C.R.

    1994-12-31

    A slide presentation is given on a distributed generation systems model developed at the Idaho National Engineering Laboratory, and its application to a situation within the Idaho Power Company`s service territory. The objectives of the work were to develop a screening model for distributed generation alternatives, to develop a better understanding of distributed generation as a utility resource, and to further INEL`s understanding of utility concerns in implementing technological change.

  19. Distributed Energy Technology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Distributed Energy Technologies Laboratory (DETL) is an extension of the power electronics testing capabilities of the Photovoltaic System Evaluation Laboratory...

  20. Learning Poisson Binomial Distributions

    OpenAIRE

    Daskalakis, Constantinos; Diakonikolas, Ilias; Servedio, Rocco A

    2015-01-01

    We consider a basic problem in unsupervised learning: learning an unknown Poisson binomial distribution. A Poisson binomial distribution (PBD) over TeX is the distribution of a sum of TeX independent Bernoulli random variables which may have arbitrary, potentially non-equal, expectations. These distributions were first studied by Poisson (Recherches sur la Probabilitè des jugements en matié criminelle et en matiére civile. Bachelier, Paris, 1837) and are a natural TeX -parameter generalizatio...

  1. Advanced air distribution

    DEFF Research Database (Denmark)

    Melikov, Arsen Krikor

    2011-01-01

    The aim of total volume air distribution (TVAD) involves achieving uniform temperature and velocity in the occupied zone and environment designed for an average occupant. The supply of large amounts of clean and cool air are needed to maintain temperature and pollution concentration at acceptable....... Ventilation in hospitals is essential to decrease the risk of airborne cross-infection. At present, mixing air distribution at a minimum of 12 ach is used in infection wards. Advanced air distribution has the potential to aid in achieving healthy, comfortable and productive indoor environments at levels...... higher than what can be achieved today with the commonly used total volume air distribution principles....

  2. Distributed Structure Searchable Toxicity

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data....

  3. Electric distribution systems

    CERN Document Server

    Sallam, A A

    2010-01-01

    "Electricity distribution is the penultimate stage in the delivery of electricity to end users. The only book that deals with the key topics of interest to distribution system engineers, Electric Distribution Systems presents a comprehensive treatment of the subject with an emphasis on both the practical and academic points of view. Reviewing traditional and cutting-edge topics, the text is useful to practicing engineers working with utility companies and industry, undergraduate graduate and students, and faculty members who wish to increase their skills in distribution system automation and monitoring."--

  4. Sorting a distribution theory

    CERN Document Server

    Mahmoud, Hosam M

    2011-01-01

    A cutting-edge look at the emerging distributional theory of sorting Research on distributions associated with sorting algorithms has grown dramatically over the last few decades, spawning many exact and limiting distributions of complexity measures for many sorting algorithms. Yet much of this information has been scattered in disparate and highly specialized sources throughout the literature. In Sorting: A Distribution Theory, leading authority Hosam Mahmoud compiles, consolidates, and clarifies the large volume of available research, providing a much-needed, comprehensive treatment of the

  5. Distribution system state estimation

    Science.gov (United States)

    Wang, Haibin

    With the development of automation in distribution systems, distribution SCADA and many other automated meters have been installed on distribution systems. Also Distribution Management System (DMS) have been further developed and more sophisticated. It is possible and useful to apply state estimation techniques to distribution systems. However, distribution systems have many features that are different from the transmission systems. Thus, the state estimation technology used in the transmission systems can not be directly used in the distribution systems. This project's goal was to develop a state estimation algorithm suitable for distribution systems. Because of the limited number of real-time measurements in the distribution systems, the state estimator can not acquire enough real-time measurements for convergence, so pseudo-measurements are necessary for a distribution system state estimator. A load estimation procedure is proposed which can provide estimates of real-time customer load profiles, which can be treated as the pseudo-measurements for state estimator. The algorithm utilizes a newly installed AMR system to calculate more accurate load estimations. A branch-current-based three-phase state estimation algorithm is developed and tested. This method chooses the magnitude and phase angle of the branch current as the state variable, and thus makes the formulation of the Jacobian matrix less complicated. The algorithm decouples the three phases, which is computationally efficient. Additionally, the algorithm is less sensitive to the line parameters than the node-voltage-based algorithms. The algorithm has been tested on three IEEE radial test feeders, both the accuracy and the convergence speed. Due to economical constraints, the number of real-time measurements that can be installed on the distribution systems is limited. So it is important to decide what kinds of measurement devices to install and where to install them. Some rules of meter placement based

  6. Serotype distribution and antimicrobial susceptibilities of Streptococcus agalactiae isolated from infected cultured tilapia (Oreochromis niloticus) in Thailand: Nine-year perspective.

    Science.gov (United States)

    Dangwetngam, Machalin; Suanyuk, Naraid; Kong, Fanrong; Phromkunthong, Wutiporn

    2016-03-01

    Streptococcus agalactiae (group B Streptococcus, GBS) infection remains a major problem associated with high mortality of cultured tilapia worldwide. The present study reports the serotype distribution and antimicrobial susceptibilities of GBS isolated from infected tilapia cultured in Thailand. One hundred and forty-four GBS isolates were identified by biochemical, serological and molecular analyses. Of these 144 GBS isolates, 126 were serotype Ia and 18 were serotype III. Antimicrobial susceptibilities of the 144 GBS isolates were determined by the disc diffusion method. Most GBS isolates were susceptible to lincomycin, norfloxacin, oxytetracycline, ampicillin, erythromycin and chloramphenicol, but resistant to oxolinic acid, gentamicin, sulfamethoxazole and trimethoprim. However, 17 isolates displayed an oxytetracycline-resistant phenotype and harboured the tet(M) gene. The broth microdilution method was used to determine the minimal inhibitory concentrations (MICs) of 17 oxytetracycline-resistant GBS isolates, and then minimal bactericidal concentrations (MBCs) of these isolates were evaluated. Oxytetracyline-resistant isolates were found to be susceptible to ampicillin, lincomycin, norfloxacin, erythromycin and chloramphenicol, with the MIC and MBC ranging from ≤ 0.125 to 0.5 μg ml- 1 and ≤ 0.125 to 2 μg ml- 1, respectively. Moreover, all 17 oxytetracycline-resistant isolates demonstrated resistance to trimethoprim, oxolinic acid, gentamicin, sulfamethoxazole and oxytetracycline, with the MIC and MBC ranging from 16 to ≥ 128 μg ml- 1 and ≥ 128 μg ml- 1, respectively. These findings are useful information for antibiotic usage in fish aquaculture. PMID:26701807

  7. Distributed High Efficiency Renewable Power Systems With Modules in Series Connection%新能源发电串联分布式高能效变换系统

    Institute of Scientific and Technical Information of China (English)

    吴红飞; 孙凯; 邢岩

    2012-01-01

    针对光伏组件、热电发电机等新能源发电模块输出电压低的特点,以系统发电功率最大化为控制目标,研究模块串联分布式新能源发电系统中的高能效模块集成变换器拓扑及其控制策略.分析不同变换器类型对系统性能和发电设备输出特性的影响;综合考虑变换器变换效率和最大功率跟踪效率,提出引入直通工作模式实现变换器全电压范围最大功率输出的控制策略和实现方法;并提出具有直通模式的改进型升降压变换器拓扑,详细分析工作模式和设计实现.搭建由13个250W模块组成的串联分布式实验系统,验证了理论分析的正确性.%The renewable power module, such as the thermoelectric generator and PV panel, features low output voltage and low power. Aiming at maximum output power, a high energy efficiency module-integrated-converter (MIC) and its control strategy for series connected distributed (SCD) renewable power system were proposed. The system structure and characteristics of the SCD renewable power system were analyzed in detail. The influence of the MIC's topologies on the renewable source and SCD power system was presented. Considering both the conversion efficiency and maximum power point tracking efficiency of the MIC, by employing a direct-connection mode, maximum output power over full output voltage range of the MIC was achieved. A high efficiency, high reliable MIC for SCD photovoltaic grid-connected power system was proposed and analyzed in detail. A SCD power system composed of 13 250W modules were built and tested. Experimental results were given to verify the analysis.

  8. Smart Distribution Systems

    Directory of Open Access Journals (Sweden)

    Yazhou Jiang

    2016-04-01

    Full Text Available The increasing importance of system reliability and resilience is changing the way distribution systems are planned and operated. To achieve a distribution system self-healing against power outages, emerging technologies and devices, such as remote-controlled switches (RCSs and smart meters, are being deployed. The higher level of automation is transforming traditional distribution systems into the smart distribution systems (SDSs of the future. The availability of data and remote control capability in SDSs provides distribution operators with an opportunity to optimize system operation and control. In this paper, the development of SDSs and resulting benefits of enhanced system capabilities are discussed. A comprehensive survey is conducted on the state-of-the-art applications of RCSs and smart meters in SDSs. Specifically, a new method, called Temporal Causal Diagram (TCD, is used to incorporate outage notifications from smart meters for enhanced outage management. To fully utilize the fast operation of RCSs, the spanning tree search algorithm is used to develop service restoration strategies. Optimal placement of RCSs and the resulting enhancement of system reliability are discussed. Distribution system resilience with respect to extreme events is presented. Test cases are used to demonstrate the benefit of SDSs. Active management of distributed generators (DGs is introduced. Future research in a smart distribution environment is proposed.

  9. Advanced Distribution Management System

    Science.gov (United States)

    Avazov, Artur R.; Sobinova, Liubov A.

    2016-02-01

    This article describes the advisability of using advanced distribution management systems in the electricity distribution networks area and considers premises of implementing ADMS within the Smart Grid era. Also, it gives the big picture of ADMS and discusses the ADMS advantages and functionalities.

  10. Software distribution using xnetlib

    Energy Technology Data Exchange (ETDEWEB)

    Dongarra, J.J. [Univ. of Tennessee, Knoxville, TN (US). Dept. of Computer Science]|[Oak Ridge National Lab., TN (US); Rowan, T.H. [Oak Ridge National Lab., TN (US); Wade, R.C. [Univ. of Tennessee, Knoxville, TN (US). Dept. of Computer Science

    1993-06-01

    Xnetlib is a new tool for software distribution. Whereas its predecessor netlib uses e-mail as the user interface to its large collection of public-domain mathematical software, xnetlib uses an X Window interface and socket-based communication. Xnetlib makes it easy to search through a large distributed collection of software and to retrieve requested software in seconds.

  11. Epicentral distribution in 2006

    Institute of Scientific and Technical Information of China (English)

    CHEN Pei-shan

    2007-01-01

    @@ For showing the epicentral distribution in and near China as well as all over the world, two epicentral maps for the earthquakes occurred last year are published annually in the 6-th issue each year. Figures 1 and 2 represent the epicentral distributions in and near China and all over the world in 2006, respectively.

  12. Epicentral distribution in 2005

    Institute of Scientific and Technical Information of China (English)

    CHEN Pei-shan

    2006-01-01

    @@ For showing the epicentral distribution in and near China as well as all over the world, two epicentral maps for the earthquakes occurred last year are published annually in the 6-th issue each year. Figures 1 and 2 represent the epicentral distributions in and near China and all over the world in 2005, respectively.

  13. Epicentral distribution in 2007

    Institute of Scientific and Technical Information of China (English)

    CHEN Pei-shan

    2008-01-01

    @@ For showing the epicentral distribution in and near China as well as all over the world, two epicentral maps for the earthquakes occurred last year are published annually in the 6-th issue each year. Figures 1 and 2 represent the epicentral distributions in and near China and all over the World in 2007, Respectively.

  14. Epicentral distribution in 2004

    Institute of Scientific and Technical Information of China (English)

    CHEN Pei-shan

    2005-01-01

    @@ For showing the epicentral distribution in and near China as well as all over the world, two epicentral maps for the earthquakes occurred last year are published annually in the 6-th issue each year. Figures 1 and 2 represent the epicentral distributions in and near China and all over the world in 2004, respectively.

  15. Groundwater and Distribution Workbook.

    Science.gov (United States)

    Ekman, John E.

    Presented is a student manual designed for the Wisconsin Vocational, Technical and Adult Education Groundwater and Distribution Training Course. This program introduces waterworks operators-in-training to basic skills and knowledge required for the operation of a groundwater distribution waterworks facility. Arranged according to the general order…

  16. Cache Oblivious Distribution Sweeping

    DEFF Research Database (Denmark)

    Brodal, G.S.; Fagerberg, R.

    2002-01-01

    We adapt the distribution sweeping method to the cache oblivious model. Distribution sweeping is the name used for a general approach for divide-and-conquer algorithms where the combination of solved subproblems can be viewed as a merging process of streams. We demonstrate by a series of algorith...

  17. Evaluating Distributed Timing Constraints

    DEFF Research Database (Denmark)

    Kristensen, C.H.; Drejer, N.

    In this paper we describe a solution to the problem of implementing time-optimal evaluation of timing constraints in distributed real-time systems.......In this paper we describe a solution to the problem of implementing time-optimal evaluation of timing constraints in distributed real-time systems....

  18. Distribution of prime numbers

    OpenAIRE

    Ouannas, Moussa

    2011-01-01

    In this paper I present the distribution of prime numbers which was treated in many researches by studying the function of Riemann; because it has a remarkable property; its non trivial zeros are prime numbers; but in this work I will show that we can find the distribution of prime numbers on remaining in natural numbers only.

  19. Metrics for Food Distribution.

    Science.gov (United States)

    Cooper, Gloria S., Ed.; Magisos, Joel H., Ed.

    Designed to meet the job-related metric measurement needs of students interested in food distribution, this instructional package is one of five for the marketing and distribution cluster, part of a set of 55 packages for metric instruction in different occupations. The package is intended for students who already know the occupational…

  20. Distributed Language and Dialogism

    DEFF Research Database (Denmark)

    Steffensen, Sune Vork

    2015-01-01

    This article takes a starting point in Per Linell’s (2013) review article on the book Distributed Language (Cowley, 2011a) and other contributions to the field of ‘Distributed Language’, including Cowley et al. (2010) and Hodges et al. (2012). The Distributed Language approach is a naturalistic and...... anti-representational approach to language that builds on recent developments in the cognitive sciences. With a starting point in Linell’s discussion of the approach, the article aims to clarify four aspects of a distributed view of language vis-à-vis the tradition of Dialogism, as presented by Linell...... (2009, 2013). First, the article discusses a central principle in Distributed Language, “the principle of non-locality,” and Linell’s interpretation of it; more generally, this is a discussion of contrasting views on “the locus of language” and derived methodological issues. Second, the article...

  1. Managing Distributed Software Projects

    DEFF Research Database (Denmark)

    Persson, John Stouby

    Increasingly, software projects are becoming geographically distributed, with limited face-toface interaction between participants. These projects face particular challenges that need careful managerial attention. This PhD study reports on how we can understand and support the management of...... distributed software projects, based on a literature study and a case study. The main emphasis of the literature study was on how to support the management of distributed software projects, but also contributed to an understanding of these projects. The main emphasis of the case study was on how to understand...... the management of distributed software projects, but also contributed to supporting the management of these projects. The literature study integrates what we know about risks and risk-resolution techniques, into a framework for managing risks in distributed contexts. This framework was developed...

  2. Distributed programming using AGAPIA

    Directory of Open Access Journals (Sweden)

    Ciprian I. Paduraru

    2014-01-01

    Full Text Available As distributed applications became more commonplace and more sophisticated, new programming languages and models for distributed programming were created. The main scope of most of these languages was to simplify the process of development by a providing a higher expressivity. This paper presents another programming language for distributed computing named AGAPIA. Its main purpose is to provide an increased expressiveness while keeping the performance close to a core programming language. To demonstrate its capabilities the paper shows the implementations of some well-known patterns specific to distribute programming along with a comparison to the corresponding MPI implementation. A complete application is presented by combining a few patterns. By taking advantage of the transparent communication model and high level statements and patterns intended to simplify the development process, the implementation of distributed programs become modular, easier to write, in clear and closer to the original solution formulation.

  3. Distributed Robotics Education

    DEFF Research Database (Denmark)

    Lund, Henrik Hautop; Pagliarini, Luigi

    2011-01-01

    Distributed robotics takes many forms, for instance, multirobots, modular robots, and self-reconfigurable robots. The understanding and development of such advanced robotic systems demand extensive knowledge in engineering and computer science. In this paper, we describe the concept...... of a distributed educational system as a valuable tool for introducing students to interactive parallel and distributed processing programming as the foundation for distributed robotics and human-robot interaction development. This is done by providing an educational tool that enables problem representation...... to be changed, related to multirobot control and human-robot interaction control from virtual to physical representation. The proposed system is valuable for bringing a vast number of issues into education – such as parallel programming, distribution, communication protocols, master dependency, connectivity...

  4. Beam distributions beyond RMS

    International Nuclear Information System (INIS)

    The beam is often represented only by its position (mean) and the width (rms = root mean squared) of its distribution. To achieve these beam parameters in a noisy condition with high backgrounds, a Gaussian distribution with offset (4 parmeters) is fitted to the measured beam distribution. This gives a very robust answer and is not very sensitive to background subtraction techniques. To get higher moments of the distribution, like skew or kurtosis, a fitting function with one or two more parameters is desired which would model the higher moments. In this paper we will concentrate on an Asymmetric Gaussian and a Super Gaussian function that will give something like the skew and the kurtosis of the distribution. This information is used to quantify special beam distribution. Some are unwanted like beam tails (skew) from transverse wakefields, higher order dispersive aberrations or potential well distortion in a damping ring. A negative kurtosis of a beam distribution describes a more rectangular, compact shape like with an over-compressed beam in z or a closed to double-homed energy distribution, while a positive kurtosis looks more like a ''Christmas tree'' and can quantify a beam mismatch after filamentation. Besides the advantages of the quantification, there are some distributions which need a further investigation like long flat tails which create background particles in a detector. In particle simulations on the other hand a simple rms number might grossly overestimate the effective size (e.g. for producing luminosity) due to a few particles which are far away from the core. This can reduce the practical gain of a big theoretical improvement in the beam size

  5. Electric power distribution handbook

    CERN Document Server

    Short, Thomas Allen

    2014-01-01

    Of the ""big three"" components of electrical infrastructure, distribution typically gets the least attention. In fact, a thorough, up-to-date treatment of the subject hasn't been published in years, yet deregulation and technical changes have increased the need for better information. Filling this void, the Electric Power Distribution Handbook delivers comprehensive, cutting-edge coverage of the electrical aspects of power distribution systems. The first few chapters of this pragmatic guidebook focus on equipment-oriented information and applications such as choosing transformer connections,

  6. Electric power distribution handbook

    CERN Document Server

    Short, Thomas Allen

    2003-01-01

    Of the ...big three... components of the electricity infrastructure, distribution typically gets the least attention, and no thorough, up-to-date treatment of the subject has been published in years. Filling that void, the Electric Power Distribution Handbook provides comprehensive information on the electrical aspects of power distribution systems. It is an unparalleled source for the background information, hard-to-find tables, graphs, methods, and statistics that power engineers need, and includes tips and solutions for problem solving and improving performance. In short, this handbook giv

  7. Distributed System Contract Monitoring

    CERN Document Server

    D, Adrian Francalanza Ph; D, Gordon Pace Ph; 10.4204/EPTCS.68.4

    2011-01-01

    The use of behavioural contracts, to specify, regulate and verify systems, is particularly relevant to runtime monitoring of distributed systems. System distribution poses major challenges to contract monitoring, from monitoring-induced information leaks to computation load balancing, communication overheads and fault-tolerance. We present mDPi, a location-aware process calculus, for reasoning about monitoring of distributed systems. We define a family of Labelled Transition Systems for this calculus, which allow formal reasoning about different monitoring strategies at different levels of abstractions. We also illustrate the expressivity of the calculus by showing how contracts in a simple contract language can be synthesised into different mDPi monitors.

  8. Simulating distributed systems

    CERN Document Server

    Newman, H B

    2001-01-01

    The simulation framework developed within the "Models of Networked Analysis at Regional Centers" (MONARC) project as a design and optimization tool for large scale distributed systems is presented. The goals are to provide a realistic simulation of distributed computing systems, customized for specific physics data processing tasks and to offer a flexible and dynamic environment to evaluate the performance of a range of possible distributed computing architectures. A detailed simulation of a large system, the CMS High Level Trigger (HLT) production farm, is also presented. (3 refs).

  9. Nonforward Parton Distributions

    CERN Document Server

    Radyushkin, A V

    1997-01-01

    Applications of perturbative QCD to deeply virtual Compton scattering and hard exclusive electroproduction processes require a generalization of usual parton distributions for the case when long-distance information is accumulated in nonforward matrix elements of quark and gluon light-cone operators. We describe two types of nonperturbative functions parametrizing such matrix elements: double distributions F(x,y;t) and nonforward distribution functions F_\\zeta (X;t), discuss their spectral properties, evolution equations which they satisfy, basic uses and general aspects of factorization for hard exclusive processes.

  10. Distributed analysis at LHCb

    International Nuclear Information System (INIS)

    The distributed analysis experience to date at LHCb has been positive: job success rates are high and wait times for high-priority jobs are low. LHCb users access the grid using the GANGA job-management package, while the LHCb virtual organization manages its resources using the DIRAC package. This clear division of labor has benefitted LHCb and its users greatly; it is a major reason why distributed analysis at LHCb has been so successful. The newly formed LHCb distributed analysis support team has also proved to be a success.

  11. Annular Flow Distribution test

    International Nuclear Information System (INIS)

    This report documents the Babcock and Wilcox (B ampersand W) Annular Flow Distribution testing for the Savannah River Laboratory (SRL). The objective of the Annular Flow Distribution Test Program is to characterize the flow distribution between annular coolant channels for the Mark-22 fuel assembly with the bottom fitting insert (BFI) in place. Flow rate measurements for each annular channel were obtained by establishing ''hydraulic similarity'' between an instrumented fuel assembly with the BFI removed and a ''reference'' fuel assembly with the BFI installed. Empirical correlations of annular flow rates were generated for a range of boundary conditions

  12. On the Conditional Distribution of the Multivariate $t$ Distribution

    OpenAIRE

    Ding, Peng

    2016-01-01

    As alternatives to the normal distributions, $t$ distributions are widely applied in robust analysis for data with outliers or heavy tails. The properties of the multivariate $t$ distribution are well documented in Kotz and Nadarajah's book, which, however, states a wrong conclusion about the conditional distribution of the multivariate $t$ distribution. Previous literature has recognized that the conditional distribution of the multivariate $t$ distribution also follows the multivariate $t$ ...

  13. Sheaves of Schwartz distributions

    International Nuclear Information System (INIS)

    The theory of sheaves is a relevant mathematical language for describing the localization principle, known to be valid for the Schwartz distributions (generalized functions). After introducing some fundamentals of sheaves and the basic facts about distribution spaces, the distribution sheaf DΩ of topological C-vector spaces over an open set Ω in Rn is systematically studied. A sheaf DM of distributions on a C∞-manifold M is then introduced, following a definition of Hoermander's for its particular elements. Further, a general definition of sheaves on a manifold, that are locally isomorphic to (or, modelled on) a sheaf on Rn, in proposed. The sheaf properties of DM are studied and this sheaf is shown to be locally isomorphic to DΩ, as a sheaf of topological vector spaces. (author). 14 refs

  14. Deciding bisimilarities on distributions

    DEFF Research Database (Denmark)

    Eisentraut, Christian; Hermanns, Holger; Krämer, Julia; Turrini, Andrea; Zhang, Lijun

    Probabilistic automata (PA) are a prominent compositional concurrency model. As a way to justify property-preserving abstractions, in the last years, bisimulation relations over probability distributions have been proposed both in the strong and the weak setting. Different to the usual bisimulation...... relations, which are defined over states, an algorithmic treatment of these relations is inherently hard, as their carrier set is uncountable, even for finite PAs. The coarsest of these relation, weak distribution bisimulation, stands out from the others in that no equivalent state-based characterisation is...... known so far. This paper presents an equivalent state-based reformulation for weak distribution bisimulation, rendering it amenable for algorithmic treatment. Then, decision procedures for the probability distribution-based bisimulation relations are presented....

  15. Distributive and Collective affixes

    DEFF Research Database (Denmark)

    Trondhjem, Naja Blytmann

    2015-01-01

    , repetition, habitual, continual and distributive/collective situations. The phasal aspectual affixes are further divided into “inner” phasal aspectual affixes with a verb-modifying function and scope over the verb stem, and “outer” phasal aspectual affixes with a sentencemodifying function and scope over the...... sentence. Most of the quantitative aspectual affixes have a verb-modifying function, and amount to about 33 affixes. Among the quantitative aspectual affixes about eleven affixes contains distributional/collective meaning. The distributional/collective affixes indicate the plurality of the first and /or...... of the affixes have very small semantic differences. Several affixes seem to have more than one meaning – a concrete meaning and an aspectual meaning. In this paper I shall give examples on how to differentiate between the distributive/ collective aspectual affixes.  ...

  16. Ribbon Seal Distribution Map

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains GIS layers that depict the known spatial distributions (i.e., ranges) and reported breeding areas of ribbon seals (Histriophoca fasciata). It...

  17. Bearded Seal Distribution Map

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains GIS layers that depict the known spatial distributions (i.e., ranges) of the two subspecies of bearded seals (Erignathus barbatus). It was...

  18. Ringed Seal Distribution Map

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains GIS layers that depict the known spatial distributions (i.e., ranges) of the five subspecies of ringed seals (Phoca hispida). It was produced...

  19. Spotted Seal Distribution Map

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains GIS layers that depict the known spatial distributions (i.e., ranges) and reported breeding areas of spotted seals (Phoca largha). It was...

  20. Financing Distributed Generation

    International Nuclear Information System (INIS)

    This paper introduces the engineer who is undertaking distributed generation projects to a wide range of financing options. Distributed generation systems (such as internal combustion engines, small gas turbines, fuel cells and photovoltaics) all require an initial investment, which is recovered over time through revenues or savings. An understanding of the cost of capital and financing structures helps the engineer develop realistic expectations and not be offended by the common requirements of financing organizations. This paper discusses several mechanisms for financing distributed generation projects: appropriations; debt (commercial bank loan); mortgage; home equity loan; limited partnership; vendor financing; general obligation bond; revenue bond; lease; Energy Savings Performance Contract; utility programs; chauffage (end-use purchase); and grants. The paper also discusses financial strategies for businesses focusing on distributed generation: venture capital; informal investors (''business angels''); bank and debt financing; and the stock market

  1. ATLAS Distributed Computing Automation

    CERN Document Server

    Schovancova, J; The ATLAS collaboration; Borrego, C; Campana, S; Di Girolamo, A; Elmsheuser, J; Hejbal, J; Kouba, T; Legger, F; Magradze, E; Medrano Llamas, R; Negri, G; Rinaldi, L; Sciacca, G; Serfon, C; Van Der Ster, D C

    2012-01-01

    The ATLAS Experiment benefits from computing resources distributed worldwide at more than 100 WLCG sites. The ATLAS Grid sites provide over 100k CPU job slots, over 100 PB of storage space on disk or tape. Monitoring of status of such a complex infrastructure is essential. The ATLAS Grid infrastructure is monitored 24/7 by two teams of shifters distributed world-wide, by the ATLAS Distributed Computing experts, and by site administrators. In this paper we summarize automation efforts performed within the ATLAS Distributed Computing team in order to reduce manpower costs and improve the reliability of the system. Different aspects of the automation process are described: from the ATLAS Grid site topology provided by the ATLAS Grid Information System, via automatic site testing by the HammerCloud, to automatic exclusion from production or analysis activities.

  2. Combustion of Fractal Distributions

    OpenAIRE

    Sotolongo, Oscar; Lopez, Enrique

    1994-01-01

    The advantages of introducing a fractal viewpoint in the field of combustion is emphasized. It is shown that the condition for perfect combustion of a collection of drops is the self-similarity of the distribution.

  3. Fuzzy barrier distributions

    International Nuclear Information System (INIS)

    Heavy-ion collisions often produce a fusion barrier distribution with structures displaying a fingerprint of couplings to highly collective excitations [1]. Basically the same distribution can be obtained from large-angle quasi-elastic scattering, though here the role of the many weak direct-reaction channels is unclear. For 20Ne + 90Zr we have observed the barrier structures expected for the highly deformed neon projectile, but for 20Ne + 92Zr we find completely smooth distribution (see Fig.1). We find that transfer channels in these systems are of similar strength but single particle excitations are significantly stronger in the latter case. They apparently reduce the 'resolving power' of the quasi-elastic channel, what leads to smeared out, or 'fuzzy' barrier distribution. This is the first case when such a phenomenon has been observed.(author)

  4. Robust Distributed Online Prediction

    CERN Document Server

    Dekel, Ofer; Shamir, Ohad; Xiao, Lin

    2010-01-01

    The standard model of online prediction deals with serial processing of inputs by a single processor. However, in large-scale online prediction problems, where inputs arrive at a high rate, an increasingly common necessity is to distribute the computation across several processors. A non-trivial challenge is to design distributed algorithms for online prediction, which maintain good regret guarantees. In \\cite{DMB}, we presented the DMB algorithm, which is a generic framework to convert any serial gradient-based online prediction algorithm into a distributed algorithm. Moreover, its regret guarantee is asymptotically optimal for smooth convex loss functions and stochastic inputs. On the flip side, it is fragile to many types of failures that are common in distributed environments. In this companion paper, we present variants of the DMB algorithm, which are resilient to many types of network failures, and tolerant to varying performance of the computing nodes.

  5. Navigating Distributed Services

    DEFF Research Database (Denmark)

    Beute, Berco

    2002-01-01

    , to a situation where they are distributedacross the Internet. The second trend is the shift from a virtual environment that solelyconsists of distributed documents to a virtual environment that consists of bothdistributed documents and distributed services. The third and final trend is theincreasing...... diversity of devices used to access information on the Internet.The focal point of the thesis is an initial exploration of the effects of the trends onusers as they navigate the virtual environment of distributed documents and services.To begin the thesis uses scenarios as a heuristic device to identify and...... analyse themain effects of the trends. This is followed by an exploration of theory of navigationInformation Spaces, which is in turn followed by an overview of theories, and the stateof the art in navigating distributed services. These explorations of both theory andpractice resulted in a large number of...

  6. Agile distributed software development

    DEFF Research Database (Denmark)

    Persson, John Stouby; Mathiassen, Lars; Aaen, Ivan

    2012-01-01

    While face-to-face interaction is fundamental in agile software development, distributed environments must rely extensively on mediated interactions. Practicing agile principles in distributed environments therefore poses particular control challenges related to balancing fixed vs. evolving quality...... requirements and people vs. process-based collaboration. To investigate these challenges, we conducted an in-depth case study of a successful agile distributed software project with participants from a Russian firm and a Danish firm. Applying Kirsch’s elements of control framework, we offer an analysis of how...... in conjunction with informal roles and relationships such as clan-like control inherent in agile development. Overall, the study demonstrates that, if appropriately applied, communication technologies can significantly support distributed, agile practices by allowing concurrent enactment of both formal...

  7. Distributed Quantum Programming

    CERN Document Server

    D'Hondt, Ellie

    2010-01-01

    In this paper we explore the structure and applicability of the Distributed Measurement Calculus (DMC), an assembly language for distributed measurement-based quantum computations. We describe the formal language's syntax and semantics, both operational and denotational, and state several properties that are crucial to the practical usability of our language, such as equivalence of our semantics, as well as compositionality and context-freeness of DMC programs. We show how to put these properties to use by constructing a composite program that implements distributed controlled operations, in the knowledge that the semantics of this program does not change under the various composition operations. Our formal model is the basis of a quantum virtual machine construction for distributed quantum computations, which we elaborate upon in the latter part of this work. This virtual machine embodies the formal semantics of DMC such that programming execution no longer needs to be analysed by hand. Far from a literal tr...

  8. Electricity Distribution Effectiveness

    OpenAIRE

    Waldemar Szpyra; Wiesław Nowak; Rafał Tarko

    2015-01-01

    This paper discusses the basic concepts of cost accounting in the power industry and selected ways of assessing the effectiveness of electricity distribution. The results of effectiveness analysis of MV/LV distribution transformer replacement are presented, and unit costs of energy transmission through various medium-voltage line types are compared. The calculation results confirm the viability of replacing transformers manufactured before 1975. Replacing transformers manufactured after...

  9. Managing Distributed Knowledge Systems

    DEFF Research Database (Denmark)

    Sørensen, Brian Vejrum; Gelbuda, Modestas

    2005-01-01

    The article argues that the growth of de novo knowledge-based organization depends on managing and coordinating increasingly growing and, therefore, distributed knowledge. Moreover, the growth in knowledge is often accompanied by an increasing organizational complexity, which is a result of....... This paper contributes to the research on organizations as distributed knowledge systems by addressing two weaknesses of the social practice literature. Firstly, it downplays the importance of formal structure and organizational design and intervention efforts by key organizational members. Secondly...

  10. Unimodality and genus distributions

    OpenAIRE

    Wan, Liangxia

    2014-01-01

    New criteria are shown that certain combinations of finite unimodal polynomials are unimodal. %Given unimodal polynomials with explicit expressions and dependent recursion relations, we propose an approach to determine their modes. As applications, unimodality of several polynomial sequences satisfying dependent recurrence relations and their modes are provided. Then unimodality of genus distributions for some ladders and crosses can be determined. As special cases, that of genus distribution...

  11. Intelligent distributed computing

    CERN Document Server

    Thampi, Sabu

    2015-01-01

    This book contains a selection of refereed and revised papers of the Intelligent Distributed Computing Track originally presented at the third International Symposium on Intelligent Informatics (ISI-2014), September 24-27, 2014, Delhi, India.  The papers selected for this Track cover several Distributed Computing and related topics including Peer-to-Peer Networks, Cloud Computing, Mobile Clouds, Wireless Sensor Networks, and their applications.

  12. Generic Distributed Simulation Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Booker, C.P.

    1999-05-14

    A Generic Distributed Simulation Architecture is described that allows a simulation to be automatically distributed over a heterogeneous network of computers and executed with very little human direction. A prototype Framework is presented that implements the elements of the Architecture and demonstrates the feasibility of the concepts. It provides a basis for a future, improved Framework that will support legacy models. Because the Framework is implemented in Java, it may be installed on almost any modern computer system.

  13. MRS parton distributions

    Energy Technology Data Exchange (ETDEWEB)

    Martin, A.D.; Stirling, W.J. [Durham Univ. (United Kingdom). Dept. of Physics; Roberts, R.G.

    1993-11-01

    The MRS parton distribution analysis is described. The latest sets are shown to give an excellent description of a wide range of deep-inelastic and other hard scattering data. Two important theoretical issues - the behaviour of the distributions at small x and the flavour structure of the quark sea - are discussed in detail. A comparison with the new structure function data from the HERA storage ring is made, and the outlook for the future is discussed. (Author).

  14. Distributed operating systems

    OpenAIRE

    Mullender, Sape J.

    1987-01-01

    In the past five years, distributed operating systems research has gone through a consolidation phase. On a large number of design issues there is now considerable consensus between different research groups. In this paper, an overview of recent research in distributed systems is given. In turn, the paper discusses overall system structure, protection issues, file system designs, problems and solutions for fault tolerance and a mechanism that is rapidly becoming very important for efficient d...

  15. Competition in electricity distribution

    International Nuclear Information System (INIS)

    The traditional view of electricity distribution is that it is a natural monopoly. Few authors have explored the question as to whether electricity distributors truly are natural monopolies or not, while observation of the current industrial practice tends to suggest that a 'market' for distribution activities does actually exist. This is a paradox for a natural monopoly. Our explanation is that monopoly characteristics well characterise the network infrastructure, but not the network operation service. (author)

  16. Logistic distribution management

    OpenAIRE

    Knytlová, Michaela

    2013-01-01

    Diploma work "Logistics distribution management" consists of two main parts: the literature review and a practical part. The literature review mostly contains information about the overall logistics, business logistics and distribution. It also contains the possibilities of using marketing, business management, and macroeconomic data while implementing a strategic business logistic plan of how to enter the new market with the existing range of production. In the literature revi...

  17. Multivariate Bernoulli distribution

    OpenAIRE

    Dai, Bin; Ding, Shilin; Wahba, Grace

    2012-01-01

    In this paper, we consider the multivariate Bernoulli distribution as a model to estimate the structure of graphs with binary nodes. This distribution is discussed in the framework of the exponential family, and its statistical properties regarding independence of the nodes are demonstrated. Importantly the model can estimate not only the main effects and pairwise interactions among the nodes but also is capable of modeling higher order interactions, allowing for the existence of complex cliq...

  18. ATLAS distributed analysis

    OpenAIRE

    Adams, David; Branco, Miguel; Albrand, Solveig; Rybkine, G.; Orellana, F.; Liko, D.; Tan C.L.; Deng, W.; C. KANNAN; Harrison Karl; Fassi, Farida; Fulachier, J.; Chetan, N.; Haeberli, C.; Soroko, A.

    2004-01-01

    The ATLAS distributed analysis (ADA) system is described. The ATLAS experiment has more that 2000 physicists from 150 insititutions in 34 countries. Users, data and processing are distributed over these sites. ADA makes use of a collection of high-level web services whose interfaces are expressed in terms of AJDL (abstract job definition language) which includes descriptions of datasets, transformations and jobs. The high-level services are implemented using generic parts...

  19. Polygamy of distributed entanglement

    OpenAIRE

    Buscemi F.; Gour G.; Kim J.S.

    2009-01-01

    While quantum entanglement is known to be monogamous (i.e. shared entanglement is restricted in multi-partite settings), here we show that distributed entanglement (or the potential for entanglement) is by nature polygamous. By establishing the concept of one-way unlocalizable entanglement (UE) and investigating its properties, we provide a polygamy inequality of distributed entanglement in tripartite quantum systems of arbitrary dimension. We also provide a polygamy inequality in multi-qubit...

  20. Distributed generation hits market

    International Nuclear Information System (INIS)

    The pace at which vendors are developing and marketing gas turbines and reciprocating engines for small-scale applications may signal the widespread growth of distributed generation. Loosely defined to refer to applications in which power generation equipment is located close to end users who have near-term power capacity needs, distributed generation encompasses a broad range of technologies and load requirements. Disagreement is inevitable, but many industry observers associate distributed generation with applications anywhere from 25 kW to 25 MW. Ten years ago, distributed generation users only represented about 2% of the world market. Today, that figure has increased to about 4 or 5%, and probably could settle in the 20% range within a 3-to-5-year period, according to Michael Jones, San Diego, Calif.-based Solar Turbines Inc. power generation marketing manager. The US Energy Information Administration predicts about 175 GW of generation capacity will be added domestically by 2010. If 20% comes from smaller plants, distributed generation could account for about 35 GW. Even with more competition, it's highly unlikely distributed generation will totally replace current market structures and central stations. Distributed generation may be best suited for making market inroads when and where central systems need upgrading, and should prove its worth when the system can't handle peak demands. Typical applications include small reciprocating engine generators at remote customer sites or larger gas turbines to boost the grid. Additional market opportunities include standby capacity, peak shaving, power quality, cogeneration and capacity rental for immediate demand requirements. Integration of distributed generation systems--using gas-fueled engines, gas-fired combustion engines and fuel cells--can upgrade power quality for customers and reduce operating costs for electric utilities

  1. Distribution and phenotypic and genotypic detection of a metallo-β-lactamase, CphA, among bacteraemic Aeromonas isolates.

    Science.gov (United States)

    Wu, Chi-Jung; Chen, Po-Lin; Wu, Jiunn-Jong; Yan, Jing-Jou; Lee, Chin-Chi; Lee, Hsin-Chun; Lee, Nan-Yao; Chang, Chia-Ming; Lin, Yu-Tzu; Chiu, Yen-Cheng; Ko, Wen-Chien

    2012-05-01

    The objectives of the study were to investigate the distribution of cphA-related genes (cphA) encoding a CphA metallo-β-lactamase (MBL) among 51 consecutive Aeromonas blood isolates and to compare different phenotypic methods for detecting CphA. The presence of cphA was detected by PCR. Four phenotypic methods, the imipenem-EDTA combined disc test, imipenem-EDTA MBL Etest, agar dilution test and modified Hodge test (MHT), were used to detect imipenem susceptibility and MBL production. The results showed that 35 (69%) blood isolates had cphA. All (100%) of 16 Aeromonas aquariorum isolates and 12 Aeromonas veronii isolates, and 4 (80%) of 5 Aeromonas hydrophila isolates, carried cphA, but none of 15 Aeromonas caviae isolates did. With the standard inocula, irrespective of the presence or absence of cphA, all but one (50, 98%) isolates were susceptible to imipenem tested by disc diffusion, Etest and agar dilution (10(4) c.f.u. spot inocula), and did not exhibit MBL production by the imipenem-EDTA combined disc test and MBL Etest. By the agar dilution test using large inocula (10(7) c.f.u.), 34 (97%) of 35 cphA(+) isolates had imipenem MICs of ≥16 µg ml(-1), higher than the susceptible breakpoint (4 µg ml(-1)), and demonstrated positive results for the MHT, while one cphA(+) and all 17 cphA(-) isolates had imipenem MICs of ≤4 µg ml(-1). In conclusion, the distribution of cphA among aeromonads is species-specific, found in A. aquariorum, A. veronii and A. hydrophila, and the MHT may be a phenotypic screening test for CphA production. PMID:22322339

  2. Distributed Self Management for Distributed Security Systems

    CERN Document Server

    Hilker, Michael

    2008-01-01

    Distributed system as e.g. artificial immune systems, complex adaptive systems, or multi-agent systems are widely used in Computer Science, e.g. for network security, optimisations, or simulations. In these systems, small entities move through the network and perform certain tasks. At some time, the entities move to another place and require therefore information where to move is most profitable. Common used systems do not provide any information or use a centralised approach where a center delegates the entities. This article discusses whether small information about the neighbours enhances the performance of the overall system or not. Therefore, two information-protocols are introduced and analysed. In addition, the protocols are implemented and tested using the artificial immune system SANA that protects a network against intrusions.

  3. The isotopic distribution conundrum.

    Science.gov (United States)

    Valkenborg, Dirk; Mertens, Inge; Lemière, Filip; Witters, Erwin; Burzykowski, Tomasz

    2012-01-01

    Although access to high-resolution mass spectrometry (MS), especially in the field of biomolecular MS, is becoming readily available due to recent advances in MS technology, the accompanied information on isotopic distribution in high-resolution spectra is not used at its full potential, mainly because of lack of knowledge and/or awareness. In this review, we give an insight into the practical problems related to calculating the isotopic distribution for large biomolecules, and present an overview of methods for the calculation of the isotopic distribution. We discuss the key events that triggered the development of various algorithms and explain the rationale of how and why the various isotopic-distribution calculations were performed. The review is focused around the developmental stages as briefly outlined below, starting with the first observation of an isotopic distribution. The observations of Beynon in the field of organic MS that chlorine appeared in a mass spectrum as two variants with odds 3:1 lie at the basis of the first wave of algorithms for the calculation of the isotopic distribution, based on the atomic composition of a molecule. From here on, we explain why more complex biomolecules such as peptides exhibit a highly complex isotope pattern when assayed by MS, and we discuss how combinatorial difficulties complicate the calculation of the isotopic distribution on computers. For this purpose, we highlight three methods, which were introduced in the 1980s. These are the stepwise procedure introduced by Kubinyi, the polynomial expansion from Brownawell and Fillippo, and the multinomial expansion from Yergey. The next development was instigated by Rockwood, who suggested to decompose the isotopic distribution in terms of their nucleon count instead of the exact mass. In this respect, we could claim that the term "aggregated" isotopic distribution is more appropriate. Due to the simplification of the isotopic distribution to its aggregated counterpart

  4. Learning Poisson Binomial Distributions

    CERN Document Server

    Daskalakis, Constantinos; Servedio, R

    2011-01-01

    We consider a basic problem in unsupervised learning: learning an unknown \\emph{Poisson Binomial Distribution} over $\\{0,1,...,n\\}$. A Poisson Binomial Distribution (PBD) is a sum $X = X_1 + ... + X_n$ of $n$ independent Bernoulli random variables which may have arbitrary expectations. We work in a framework where the learner is given access to independent draws from the distribution and must (with high probability) output a hypothesis distribution which has total variation distance at most $\\eps$ from the unknown target PBD. As our main result we give a highly efficient algorithm which learns to $\\eps$-accuracy using $\\tilde{O}(1/\\eps^3)$ samples independent of $n$. The running time of the algorithm is \\emph{quasilinear} in the size of its input data, i.e. $\\tilde{O}(\\log(n)/\\eps^3)$ bit-operations (observe that each draw from the distribution is a $\\log(n)$-bit string). This is nearly optimal since any algorithm must use $\\Omega(1/\\eps^2)$ samples. We also give positive and negative results for some extensi...

  5. Distributed replica dynamics

    Science.gov (United States)

    Zhang, Liang; Chill, Samuel T.; Henkelman, Graeme

    2015-11-01

    A distributed replica dynamics (DRD) method is proposed to calculate rare-event molecular dynamics using distributed computational resources. Similar to Voter's parallel replica dynamics (PRD) method, the dynamics of independent replicas of the system are calculated on different computational clients. In DRD, each replica runs molecular dynamics from an initial state for a fixed simulation time and then reports information about the trajectory back to the server. A simulation clock on the server accumulates the simulation time of each replica until one reports a transition to a new state. Subsequent calculations are initiated from within this new state and the process is repeated to follow the state-to-state evolution of the system. DRD is designed to work with asynchronous and distributed computing resources in which the clients may not be able to communicate with each other. Additionally, clients can be added or removed from the simulation at any point in the calculation. Even with heterogeneous computing clients, we prove that the DRD method reproduces the correct probability distribution of escape times. We also show this correspondence numerically; molecular dynamics simulations of Al(100) adatom diffusion using PRD and DRD give consistent exponential distributions of escape times. Finally, we discuss guidelines for choosing the optimal number of replicas and replica trajectory length for the DRD method.

  6. An Extended Pareto Distribution

    Directory of Open Access Journals (Sweden)

    Mohamad Mead

    2014-10-01

    Full Text Available For the first time, a new continuous distribution, called the generalized beta exponentiated Pareto type I (GBEP [McDonald exponentiated Pareto] distribution, is defined and investigated. The new distribution contains as special sub-models some well-known and not known distributions, such as the generalized beta Pareto (GBP [McDonald Pareto], the Kumaraswamy exponentiated Pareto (KEP, Kumaraswamy Pareto (KP, beta exponentiated Pareto (BEP, beta Pareto (BP, exponentiated Pareto (EP and Pareto, among several others. Various structural properties of the new distribution are derived, including explicit expressions for the moments, moment generating function, incomplete moments, quantile function, mean deviations and Rényi entropy. Lorenz, Bonferroni and Zenga curves are derived. The method of maximum likelihood is proposed for estimating the model parameters. We obtain the observed information matrix. The usefulness of the new model is illustrated by means of two real data sets. We hope that this generalization may attract wider applications in reliability, biology and lifetime data analysis.

  7. Distributed processor systems

    International Nuclear Information System (INIS)

    In recent years, there has been a growing tendency in high-energy physics and in other fields to solve computational problems by distributing tasks among the resources of inter-coupled processing devices and associated system elements. This trend has gained further momentum more recently with the increased availability of low-cost processors and with the development of the means of data distribution. In two lectures, the broad question of distributed computing systems is examined and the historical development of such systems reviewed. An attempt is made to examine the reasons for the existence of these systems and to discern the main trends for the future. The components of distributed systems are discussed in some detail and particular emphasis is placed on the importance of standards and conventions in certain key system components. The ideas and principles of distributed systems are discussed in general terms, but these are illustrated by a number of concrete examples drawn from the context of the high-energy physics environment. (Auth.)

  8. Moment Distributions of Phase Type

    DEFF Research Database (Denmark)

    Bladt, Mogens; Nielsen, Bo Friis

    In this paper we prove that the class of distributions on the positive reals with a rational Laplace transform, also known as matrix-exponential distributions, is closed under formation of moment distributions. In particular, the results are hence valid for the well known class of phase-type dist......In this paper we prove that the class of distributions on the positive reals with a rational Laplace transform, also known as matrix-exponential distributions, is closed under formation of moment distributions. In particular, the results are hence valid for the well known class of phase......-type distributions. We construct representations for moment distributions based on a general matrix-exponential distribution which turns out to be a generalization of the moment distributions based on exponential distributions. For moment distributions based on phase{type distributions we find an appropriate...

  9. On exchangeable multinomial distributions

    Science.gov (United States)

    George, E. Olusegun; Cheon, Kyeongmi; Yuan, Yilian; Szabo, Aniko

    2016-01-01

    We derive an expression for the joint distribution of exchangeable multinomial random variables, which generalizes the multinomial distribution based on independent trials while retaining some of its important properties. Unlike de Finneti's representation theorem for a binary sequence, the exchangeable multinomial distribution derived here does not require that the finite set of random variables under consideration be a subset of an infinite sequence. Using expressions for higher moments and correlations, we show that the covariance matrix for exchangeable multinomial data has a different form from that usually assumed in the literature, and we analyse data from developmental toxicology studies. The proposed analyses have been implemented in R and are available on CRAN in the CorrBin package.

  10. Electricity Distribution Effectiveness

    Directory of Open Access Journals (Sweden)

    Waldemar Szpyra

    2015-12-01

    Full Text Available This paper discusses the basic concepts of cost accounting in the power industry and selected ways of assessing the effectiveness of electricity distribution. The results of effectiveness analysis of MV/LV distribution transformer replacement are presented, and unit costs of energy transmission through various medium-voltage line types are compared. The calculation results confirm the viability of replacing transformers manufactured before 1975. Replacing transformers manufactured after 1975 – only to reduce energy losses – is not economically justified. Increasing use of a PAS type line for energy transmission in local distribution networks is reasonable. Cabling these networks under the current calculation rules of discounts for excessive power outages is not viable, even in areas particularly exposed to catastrophic wire icing.

  11. Industrial power distribution

    CERN Document Server

    Fehr, Ralph

    2016-01-01

    In this fully updated version of Industrial Power Distribution, the author addresses key areas of electric power distribution from an end-user perspective for both electrical engineers, as well as students who are training for a career in the electrical power engineering field. Industrial Power Distribution, Second Edition, begins by describing how industrial facilities are supplied from utility sources, which is supported with background information on the components of AC power, voltage drop calculations, and the sizing of conductors and transformers. Important concepts and discussions are featured throughout the book including those for sequence networks, ladder logic, motor application, fault calculations, and transformer connections. The book concludes with an introduction to power quality, how it affects industrial power systems, and an expansion of the concept of power factor, including a distortion term made necessary by the existence of harmonic.

  12. Distributed System Contract Monitoring

    Directory of Open Access Journals (Sweden)

    Adrian Francalanza Ph.D

    2011-09-01

    Full Text Available The use of behavioural contracts, to specify, regulate and verify systems, is particularly relevant to runtime monitoring of distributed systems. System distribution poses major challenges to contract monitoring, from monitoring-induced information leaks to computation load balancing, communication overheads and fault-tolerance. We present mDPi, a location-aware process calculus, for reasoning about monitoring of distributed systems. We define a family of Labelled Transition Systems for this calculus, which allow formal reasoning about different monitoring strategies at different levels of abstractions. We also illustrate the expressivity of the calculus by showing how contracts in a simple contract language can be synthesised into different mDPi monitors.

  13. Distributed Wind Market Applications

    Energy Technology Data Exchange (ETDEWEB)

    Forsyth, T.; Baring-Gould, I.

    2007-11-01

    Distributed wind energy systems provide clean, renewable power for on-site use and help relieve pressure on the power grid while providing jobs and contributing to energy security for homes, farms, schools, factories, private and public facilities, distribution utilities, and remote locations. America pioneered small wind technology in the 1920s, and it is the only renewable energy industry segment that the United States still dominates in technology, manufacturing, and world market share. The series of analyses covered by this report were conducted to assess some of the most likely ways that advanced wind turbines could be utilized apart from large, central station power systems. Each chapter represents a final report on specific market segments written by leading experts in this field. As such, this document does not speak with one voice but rather a compendium of different perspectives, which are documented from a variety of people in the U.S. distributed wind field.

  14. ATLAS Distributed Computing

    CERN Document Server

    Schovancova, J; The ATLAS collaboration

    2011-01-01

    The poster details the different aspects of the ATLAS Distributed Computing experience after the first year of LHC data taking. We describe the performance of the ATLAS distributed computing system and the lessons learned during the 2010 run, pointing out parts of the system which were in a good shape, and also spotting areas which required improvements. Improvements ranged from hardware upgrade on the ATLAS Tier-0 computing pools to improve data distribution rates, tuning of FTS channels between CERN and Tier-1s, and studying data access patterns for Grid analysis to improve the global processing rate. We show recent software development driven by operational needs with emphasis on data management and job execution in the ATLAS production system.

  15. Nonequilibrium distributions in superconductors

    International Nuclear Information System (INIS)

    The nonequilibrium distribution functions of quasiparticles and phonons in superconductors are calculated for various cases. The conditions at which the nonequilibrium distributions exist are found. The dependences of the temperature and concentration of excitations on the pumping intensity, the sample thickness, and other parameters of the superconductor are calculated. In the current state the dependences of these quantities on the superfluid velocity and the current are investigated, and it is found that the dependence T(v/sub s/) has a minimum, and the current for v/sub s/>v/sup(1)/sub s/o becomes negative. It is also shown that in the nonequilibrium superconductor the state with v/sub s/*not =0 and J(v/sub s/*) =0 may exist. We have determined the nonequilibrium distribution function for a tunnel junction and investigated the V-A characteristic at some conditions for which an absolute negative resistance may exist

  16. A distribution network review

    Energy Technology Data Exchange (ETDEWEB)

    Fairbairn, R.J.; Maunder, D.; Kenyon, P.

    1999-07-01

    This report summarises the findings of a study reviewing the distribution network in England, Scotland and Wales to evaluate its ability to accommodate more embedded generation from both fossil fuel and renewable energy sources. The background to the study is traced, and descriptions of the existing electricity supply system, the licence conditions relating to embedded generation, and the effects of the Review of Electricity Trading Arrangements are given. The ability of the UK distribution networks to accept embedded generation is examined, and technical benefits/drawbacks arising from embedded generation, and the potential for uptake of embedded generation technologies are considered. The distribution network capacity and the potential uptake of embedded generation are compared, and possible solutions to overcome obstacles are suggested. (UK)

  17. Distributed photovoltaic grid transformers

    CERN Document Server

    Shertukde, Hemchandra Madhusudan

    2014-01-01

    The demand for alternative energy sources fuels the need for electric power and controls engineers to possess a practical understanding of transformers suitable for solar energy. Meeting that need, Distributed Photovoltaic Grid Transformers begins by explaining the basic theory behind transformers in the solar power arena, and then progresses to describe the development, manufacture, and sale of distributed photovoltaic (PV) grid transformers, which help boost the electric DC voltage (generally at 30 volts) harnessed by a PV panel to a higher level (generally at 115 volts or higher) once it is

  18. Liquidity, welfare and distribution

    Directory of Open Access Journals (Sweden)

    Martín Gil Samuel

    2012-01-01

    Full Text Available This work presents a dynamic general equilibrium model where wealth distribution is endogenous. I provide channels of causality that suggest a complex relationship between financial markets and the real activity which breaks down the classical dichotomy. As a consequence, the Friedman rule does not hold. In terms of the current events taking place in the world economy, this paper provides a rationale to advert against the perils of an economy satiated with liquidity. Efficiency and distribution cannot thus be considered as separate attributes once we account for the interactions between financial markets and the economic performance.

  19. Decentralized Distributed Bayesian Estimation

    Czech Academy of Sciences Publication Activity Database

    Dedecius, Kamil; Sečkárová, Vladimíra

    Praha: ÚTIA AVČR, v.v.i, 2011 - (Janžura, M.; Ivánek, J.). s. 16-16 [7th International Workshop on Data–Algorithms–Decision Making. 27.11.2011-29.11.2011, Mariánská] R&D Projects: GA ČR 102/08/0567; GA ČR GA102/08/0567 Institutional research plan: CEZ:AV0Z10750506 Keywords : estimation * distributed estimation * model Subject RIV: BB - Applied Statistics, Operational Research http://library.utia.cas.cz/separaty/2011/AS/dedecius-decentralized distributed bayesian estimation.pdf

  20. Definition of distributed generation

    International Nuclear Information System (INIS)

    Today, power systems in many countries are restructured and deregulated and it is expected the small scale generators or Distributed Generations (DG), such as Micro turbines, PV, fuel cells, wind turbines and so on will play important role in power system. So it is necessary to be well defined and described. Generally, DGs are defined as electric power generators that are connected to distribution networks or on the customer side of networks. This paper presents a definition of DGs with considering some important aspects, and after that introduces some different type of DGs

  1. New parton distributions

    Energy Technology Data Exchange (ETDEWEB)

    Martin, A.D.; Stirling, W.J. (Dept. of Physics, Univ. Durham (United Kingdom)); Roberts, R.G. (Rutherford Appleton Lab., Chilton (United Kingdom))

    1992-12-01

    Recent measurements of the structure functions for deep inelastic scattering made by the NMC and the CCFR collaboration provide new information on parton distribution, particularly in the 0.01<[chi]<0.1 interval. We describe (next-to-leading order) determinations of parton distributions which incorporate these new data together with other deep-inelastic and related data, and which allow the possibility of flavour dependence of the light quark sea (i.e. anti u[ne]anti d) as implied by the Gottfried sum rule. We discuss extrapolations to small [chi]. (orig.).

  2. The Signal Distribution System

    CERN Document Server

    Belohrad, D; CERN. Geneva. AB Department

    2005-01-01

    For the purpose of LHC signal observation and high frequency signal distribution, the Signal Distribution System (SDS) was built. The SDS can contain up to 5 switching elements, where each element allows the user to switch between one of the maximum 8 bi-directional signals. The coaxial relays are used to switch the signals. Depending of the coaxial relay type used, the transfer bandwidth can go up to 18GHz. The SDS is controllable via TCP/IP, parallel port, or locally by rotary switch.

  3. Theory of distributions

    CERN Document Server

    Georgiev, Svetlin G

    2015-01-01

    This book explains many fundamental ideas on the theory of distributions. The theory of partial differential equations is one of the synthetic branches of analysis that combines ideas and methods from different fields of mathematics, ranging from functional analysis and harmonic analysis to differential geometry and topology. This presents specific difficulties to those studying this field. This book, which consists of 10 chapters, is suitable for upper undergraduate/graduate students and mathematicians seeking an accessible introduction to some aspects of the theory of distributions. It can also be used for one-semester course.

  4. Distributed Control Diffusion

    DEFF Research Database (Denmark)

    Schultz, Ulrik Pagh

    2007-01-01

    . Programming a modular, self-reconfigurable robot is however a complicated task: the robot is essentially a real-time, distributed embedded system, where control and communication paths often are tightly coupled to the current physical configuration of the robot. To facilitate the task of programming modular....... The prototype relies on a simple virtual machine with a dedicated instruction set, allowing mobile programs to migrate between the modules that constitute a robot. Through a number of simulated experiments, we should how a single rule-based controller program implemented using distributed control diffusion can...

  5. High voltage distributed amplifier

    Science.gov (United States)

    Willems, D.; Bahl, I.; Wirsing, K.

    1991-12-01

    A high-voltage distributed amplifier implemented in GaAs MMIC technology has demonstrated good circuit performance over at least two octave bandwidth. This technique allows for very broadband amplifier operation with good efficiency in satellite, active-aperture radar, and battery-powered systems. Also, by increasing the number of FETs, the amplifier can be designed to match different voltage rails. The circuit does require a small amount of additional chip size over conventional distributed amplifiers but does not require power dividers or additional matching networks. This circuit configuration should find great use in broadband power amplifier design.

  6. THERMAL DISTRIBUTION SYSTEM EXPERIMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRAJEWSKI,R.F.; ANDREWS,J.W.; WEI,G.

    1999-09-01

    A laboratory experiment has been conducted which tests for the effects of distribution system purging on system Delivery Effectiveness (DE) as defined in ASHRAE 152P. The experiment is described in its configuration, instrumentation, and data acquisition system. Data gathered in the experiment is given and discussed. The results show that purging of the distribution system alone does not offer any improvement of the system DE. Additional supporting tests were conducted regarding experimental simulations of buffer zones and bare pipe and are also discussed.

  7. Distributed User Interfaces

    CERN Document Server

    Gallud, Jose A; Penichet, Victor M R

    2011-01-01

    The recent advances in display technologies and mobile devices is having an important effect on the way users interact with all kinds of devices (computers, mobile devices, laptops, tablets, and so on). These are opening up new possibilities for interaction, including the distribution of the UI (User Interface) amongst different devices, and implies that the UI can be split and composed, moved, copied or cloned among devices running the same or different operating systems. These new ways of manipulating the UI are considered under the emerging topic of Distributed User Interfaces (DUIs). DUIs

  8. FMCG companies specific distribution channels

    OpenAIRE

    Ioana Barin

    2009-01-01

    Distribution includes all activities undertaken by the producer, alone or in cooperation, since the end of the final finished products or services until they are in possession of consumers. The distribution consists of the following major components: distribution channels or marketing channels, which together form a distribution network; logistics o rphysical distribution. In order to effective achieve, distribution of goods requires an amount of activities and operational processes related t...

  9. Factor Determining Income Distribution

    NARCIS (Netherlands)

    J. Tinbergen (Jan)

    1972-01-01

    textabstractSince the phrase income distribution covers a large number of different concepts, it is necessary to define these and to indicate the choice made in this article. Income for a given recipient may cover lists of items which are not always the same. Apart from popular misunderstandings abo

  10. Asynchronous Distributed Searchlight Scheduling

    CERN Document Server

    Obermeyer, Karl J; Bullo, Francesco

    2011-01-01

    This paper develops and compares two simple asynchronous distributed searchlight scheduling algorithms for multiple robotic agents in nonconvex polygonal environments. A searchlight is a ray emitted by an agent which cannot penetrate the boundary of the environment. A point is detected by a searchlight if and only if the point is on the ray at some instant. Targets are points which can move continuously with unbounded speed. The objective of the proposed algorithms is for the agents to coordinate the slewing (rotation about a point) of their searchlights in a distributed manner, i.e., using only local sensing and limited communication, such that any target will necessarily be detected in finite time. The first algorithm we develop, called the DOWSS (Distributed One Way Sweep Strategy), is a distributed version of a known algorithm described originally in 1990 by Sugihara et al \\cite{KS-IS-MY:90}, but it can be very slow in clearing the entire environment because only one searchlight may slew at a time. In an ...

  11. Enabling distributed petascale science

    International Nuclear Information System (INIS)

    Petascale science is an end-to-end endeavour, involving not only the creation of massive datasets at supercomputers or experimental facilities, but the subsequent analysis of that data by a user community that may be distributed across many laboratories and universities. The new SciDAC Center for Enabling Distributed Petascale Science (CEDPS) is developing tools to support this end-to-end process. These tools include data placement services for the reliable, high-performance, secure, and policy-driven placement of data within a distributed science environment; tools and techniques for the construction, operation, and provisioning of scalable science services; and tools for the detection and diagnosis of failures in end-to-end data placement and distributed application hosting configurations. In each area, we build on a strong base of existing technology and have made useful progress in the first year of the project. For example, we have recently achieved order-of-magnitude improvements in transfer times (for lots of small files) and implemented asynchronous data staging capabilities; demonstrated dynamic deployment of complex application stacks for the STAR experiment; and designed and deployed end-to-end troubleshooting services. We look forward to working with SciDAC application and technology projects to realize the promise of petascale science

  12. Industrial power distribution

    Energy Technology Data Exchange (ETDEWEB)

    Sorrells, M.A.

    1990-01-01

    This paper is a broad overview of industrial power distribution. Primary focus will be on selection of the various low voltage components to achieve the end product. Emphasis will be on the use of national standards to ensure a safe and well designed installation.

  13. A MULTIVARIATE WEIBULL DISTRIBUTION

    Directory of Open Access Journals (Sweden)

    Cheng Lee

    2010-07-01

    Full Text Available A multivariate survival function of Weibull Distribution is developed by expanding the theorem by Lu and Bhattacharyya. From the survival function, the probability density function, the cumulative probability function, the determinant of the Jacobian Matrix, and the general moment are derived.

  14. Quantum statistical parton distributions

    International Nuclear Information System (INIS)

    Modified Fermi-Dirac functions for the fermionic partons and a Bose-Einstein expression for gluons allow us to successfully describe both polarized and unpolarized structure functions in terms of a small number of parameters. Definite predictions are made for q-bar distributions to be tested in forthcoming experiments. (author)

  15. Quantum statistical parton distributions

    Energy Technology Data Exchange (ETDEWEB)

    Buccella, Franco [Dipartimento di Scienze Fisiche, Universita di Napoli Federico II, INFN, Sezione di Napoli (Italy)

    2002-10-11

    Modified Fermi-Dirac functions for the fermionic partons and a Bose-Einstein expression for gluons allow us to successfully describe both polarized and unpolarized structure functions in terms of a small number of parameters. Definite predictions are made for q-bar distributions to be tested in forthcoming experiments. (author)

  16. Parton distributions updated

    Energy Technology Data Exchange (ETDEWEB)

    Martin, A.D.; Stirling, W.J. [Durham Univ. (United Kingdom). Dept. of Physics; Roberts, R.G.

    1992-11-01

    We refine our recent determination of parton distributions with the inclusion of the new published sets of precise muon and neutrino deep inelastic data. Deuteron screening effects are incorporated. The tt-bar cross section at the Fermi National Accelerator Laboratory (FNAL) pp-bar collider is calculated. (author).

  17. Power distribution arrangement

    DEFF Research Database (Denmark)

    2010-01-01

    An arrangement and a method for distributing power supplied by a power source to two or more of loads (e.g., electrical vehicular systems) is disclosed, where a representation of the power taken by a particular one of the loads from the source is measured. The measured representation of the amount...

  18. A Distributed Tier-1

    DEFF Research Database (Denmark)

    Fischer, Lars; Grønager, Michael; Kleist, Josva;

    2008-01-01

    organization but instead is a meta-center built of resources under the control of a number of different national organizations. We present some technical implications of these aspects as well as the high-level design of this distributed Tier-1. The focus will be on computing services, storage and monitoring....

  19. Distributed analysis in ATLAS

    Science.gov (United States)

    Dewhurst, A.; Legger, F.

    2015-12-01

    The ATLAS experiment accumulated more than 140 PB of data during the first run of the Large Hadron Collider (LHC) at CERN. The analysis of such an amount of data is a challenging task for the distributed physics community. The Distributed Analysis (DA) system of the ATLAS experiment is an established and stable component of the ATLAS distributed computing operations. About half a million user jobs are running daily on DA resources, submitted by more than 1500 ATLAS physicists. The reliability of the DA system during the first run of the LHC and the following shutdown period has been high thanks to the continuous automatic validation of the distributed analysis sites and the user support provided by a dedicated team of expert shifters. During the LHC shutdown, the ATLAS computing model has undergone several changes to improve the analysis workflows, including the re-design of the production system, a new analysis data format and event model, and the development of common reduction and analysis frameworks. We report on the impact such changes have on the DA infrastructure, describe the new DA components, and include recent performance measurements.

  20. Distributed analysis in ATLAS

    CERN Document Server

    Legger, Federica; The ATLAS collaboration

    2015-01-01

    The ATLAS experiment accumulated more than 140 PB of data during the first run of the Large Hadron Collider (LHC) at CERN. The analysis of such an amount of data for the distributed physics community is a challenging task. The Distributed Analysis (DA) system of the ATLAS experiment is an established and stable component of the ATLAS distributed computing operations. About half a million user jobs are daily running on DA resources, submitted by more than 1500 ATLAS physicists. The reliability of the DA system during the first run of the LHC and the following shutdown period has been high thanks to the continuous automatic validation of the distributed analysis sites and the user support provided by a dedicated team of expert shifters. During the LHC shutdown, the ATLAS computing model has undergone several changes to improve the analysis workflows, including the re-design of the production system, a new analysis data format and event model, and the development of common reduction and analysis frameworks. We r...

  1. The proton's gluon distribution

    OpenAIRE

    Donnachie, A.; Landshoff, P.V.(DAMTP, Cambridge University, United Kingdom)

    2002-01-01

    The gluon distribution is dominated by the hard pomeron at small $x$ and all $Q^2$, with no soft-pomeron contribution. This describes well not only the DGLAP evolution of the hard-pomeron part of $F_2(x,Q^2)$, but also charm photoproduction and electroproduction, and the longitudinal structure function, all calculated in leading-order pQCD.

  2. Distributed Parameter Modelling Applications

    DEFF Research Database (Denmark)

    Sales-Cruz, Mauricio; Cameron, Ian; Gani, Rafiqul

    2011-01-01

    development of a short-path evaporator. The oil shale processing problem illustrates the interplay amongst particle flows in rotating drums, heat and mass transfer between solid and gas phases. The industrial application considers the dynamics of an Alberta-Taciuk processor, commonly used in shale oil and oil...... the steady state, distributed behaviour of a short-path evaporator....

  3. Characterizations of Exponentiated Distributions

    OpenAIRE

    gholamhossein g hamedani

    2013-01-01

    Variuos characterizations of the class of exponentiated distributions are presented.  These characterizations are based on a simple relationship between two truncated moments and based on functions of the nth order statistic.  The results are applied to certain well-known members of this class.

  4. Antimycobacterial activity evaluation and MIC determination of liophilizated hydroalcoholic extracts of Bixa orellana L., Bixaceae Avaliação da atividade antimicobacteriana e a determinação da CIM de extratos hidroalcoólicos liofilizados de Bixa orellana L., Bixaceae

    Directory of Open Access Journals (Sweden)

    Renata B. Silva

    2010-05-01

    Full Text Available Bixa orellana is used in popular medicine against several diseases. Extracts of its fruit, root and leaf presented antimicrobial activity, while seed extract showed negative results. This study aimed at verifying the antimycobacterial activity of B. orellanalyophilized hydroalcoholic extracts over Mycobacterium tuberculosis, and determine the Minimum Inhibitory Concentration against five bacteria. Antimycobacterial activity was determined by diffusion technique, while MIC was assessed by diffusion and colorimetric analysis. MICs were 0.3, 0.5 and 0.2 mg/mL respectively, for leaf, root and stem extracts, against M. tuberculosis. Stem's extract showed 1.2 mg/mL for B. cereus, 1.53 mg/mL for S. aureusand S. typhimurium, 4.50 mg/mL for P. aeruginosaand 8.01 mg/mL for P. mirabillis.Leaf extracts showed 0.66 mg/mL for P. aeruginosa, 0.94 mg/mL for P. mirabillis, 1.88 mg/mL for S. aureus, 3.95 mg/mL for B. cereusand 8.37 mg/mL for S. typhimurium. Root's extracts showed 0.25 mg/mL for P. aeruginosa,0.31 mg/mL for S. aureus, 0.62 mg/mL for S. typhimuriumand 3.00 mg/mL for B. cereusand P. mirabillis. Leaf and stem extracts showed antimycobacterial activity. MICs were lower in colorimetric analysis than in agar diffusion. Extracts revealed bacteriostatic activity against the five bacterial.Bixa orellana é usada na medicina popular em várias doenças. Extratos do fruto, raiz e folhas apresentaram atividade antimicrobiana, enquanto extratos do caule mostraram resultados negativos. Este estudo teve por objetivo verificar a atividade antimicobacteriana de extratos hidroalcoólicos liofilizados de B. orellanafrente Mycobacterium tuberculosis e determinar a Concentração Inibitória Mínima para cinco bactérias. A atividade antimicobacteriana foi determinada por difusão e a CIM por difusão e análise colorimétrica. As CIM foram 0,3, 0,5 e 0,2 mg/mL para os extratos de folhas, raiz e caule frente M. tuberculosis. Os extratos de caule demonstraram CIM de 1

  5. Multiagent distributed watershed management

    Science.gov (United States)

    Giuliani, M.; Castelletti, A.; Amigoni, F.; Cai, X.

    2012-04-01

    Deregulation and democratization of water along with increasing environmental awareness are challenging integrated water resources planning and management worldwide. The traditional centralized approach to water management, as described in much of water resources literature, is often unfeasible in most of the modern social and institutional contexts. Thus it should be reconsidered from a more realistic and distributed perspective, in order to account for the presence of multiple and often independent Decision Makers (DMs) and many conflicting stakeholders. Game theory based approaches are often used to study these situations of conflict (Madani, 2010), but they are limited to a descriptive perspective. Multiagent systems (see Wooldridge, 2009), instead, seem to be a more suitable paradigm because they naturally allow to represent a set of self-interested agents (DMs and/or stakeholders) acting in a distributed decision process at the agent level, resulting in a promising compromise alternative between the ideal centralized solution and the actual uncoordinated practices. Casting a water management problem in a multiagent framework allows to exploit the techniques and methods that are already available in this field for solving distributed optimization problems. In particular, in Distributed Constraint Satisfaction Problems (DCSP, see Yokoo et al., 2000), each agent controls some variables according to his own utility function but has to satisfy inter-agent constraints; while in Distributed Constraint Optimization Problems (DCOP, see Modi et al., 2005), the problem is generalized by introducing a global objective function to be optimized that requires a coordination mechanism between the agents. In this work, we apply a DCSP-DCOP based approach to model a steady state hypothetical watershed management problem (Yang et al., 2009), involving several active human agents (i.e. agents who make decisions) and reactive ecological agents (i.e. agents representing

  6. A distribution management system

    Energy Technology Data Exchange (ETDEWEB)

    Jaerventausta, P.; Verho, P.; Kaerenlampi, M.; Pitkaenen, M. [Tampere Univ. of Technology (Finland); Partanen, J. [Lappeenranta Univ. of Technology (Finland)

    1998-08-01

    The development of new distribution automation applications is considerably wide nowadays. One of the most interesting areas is the development of a distribution management system (DMS) as an expansion to the traditional SCADA system. At the power transmission level such a system is called an energy management system (EMS). The idea of these expansions is to provide supporting tools for control center operators in system analysis and operation planning. Nowadays the SCADA is the main computer system (and often the only) in the control center. However, the information displayed by the SCADA is often inadequate, and several tasks cannot be solved by a conventional SCADA system. A need for new computer applications in control center arises from the insufficiency of the SCADA and some other trends. The latter means that the overall importance of the distribution networks is increasing. The slowing down of load-growth has often made network reinforcements unprofitable. Thus the existing network must be operated more efficiently. At the same time larger distribution areas are for economical reasons being monitored at one control center and the size of the operation staff is decreasing. The quality of supply requirements are also becoming stricter. The needed data for new applications is mainly available in some existing systems. Thus the computer systems of utilities must be integrated. The main data source for the new applications in the control center are the AM/FM/GIS (i.e. the network database system), the SCADA, and the customer information system (CIS). The new functions can be embedded in some existing computer system. This means a strong dependency on the vendor of the existing system. An alternative strategy is to develop an independent system which is integrated with other computer systems using well-defined interfaces. The latter approach makes it possible to use the new applications in various computer environments, having only a weak dependency on the

  7. Summer Steelhead Distribution [ds341

    Data.gov (United States)

    California Department of Resources — Summer Steelhead Distribution October 2009 Version This dataset depicts observation-based stream-level geographic distribution of anadromous summer-run steelhead...

  8. Distribution management system

    Energy Technology Data Exchange (ETDEWEB)

    Verho, P.; Kaerenlampi, M.; Pitkaenen, M.; Jaerventausta, P.; Partanen, J.

    1997-12-31

    This report comprises a general description of the results obtained in the research projects `Information system applications of a distribution control center`, `Event analysis in primary substation`, and `Distribution management system` of the EDISON research program during the years of 1993 - 1997. The different domains of the project are presented in more detail in other reports. An operational state analysis of a distribution network has been made from the control center point of view and the functions which can not be solved by a conventional SCADA system are determined. The basis for new computer applications is shown to be integration of the computer systems. The main result of the work is a distribution management system (DMS), which is an autonomous system integrated to the existing information systems, SCADA and AM/FM/GIS. The system uses a large number of modelling and computation methods and provides an extensive group of advanced functions to support the distribution network monitoring, fault management, operations planning and optimization. The development platform of the system consists of a Visual C++ programming environment, Windows NT operating system and PC. During the development the DMS has been tested in a pilot utility and it is nowadays in practical use in several Finnish utilities. The use of a DMS improves the quality and economy of power supply in many ways; the outage times can, in particular, be reduced using the system. Based on the achieved experiences some parts of the DMS reached the commercialization phase, too. Initially the commercial products were developed by a software company, Versoft Oy. At present the research results are the basis of a worldwide software product supplied by ABB Transmit Co. (orig.) EDISON Research Programme. 28 refs.

  9. Modeling of magnitude distributions by the generalized truncated exponential distribution

    CERN Document Server

    Raschke, Mathias

    2014-01-01

    The probability distribution of the magnitude can be modeled by an exponential distribution according to the Gutenberg-Richter relation. Two alternatives are the truncated exponential distribution (TED) and the cut-off exponential distribution (CED). The TED is frequently used in seismic hazard analysis although it has a weak point: When two TEDs with equal parameters excepting the upper bound magnitude are mixed, then the resulting distribution is not a TED. Inversely, it is also not possible to split a TED of a seismic region in TEDs of sub-regions with equal parameters excepting the upper bound magnitude. This weakness is a principal problem as seismic regions are constructed scientific objects and not natural units. We overcome it by the generalization of the above-mentioned exponential distributions: the generalized truncated exponential distribution (GTED). Therein, identical exponential distributions are mixed by the probability distribution of the correct cut-off points. This distribution model is fle...

  10. Frequency distribution of coliforms in water distribution systems.

    OpenAIRE

    Christian, R R; Pipes, W O

    1983-01-01

    Nine small water distribution systems were sampled intensively to determine the patterns of dispersion of coliforms. The frequency distributions of confirmed coliform counts were compatible with either the negative-binomial or the lognormal distribution. They were not compatible with either the Poisson or Poisson-plus-added zeroes distribution. The implications of the use of the lognormal distributional model were further evaluated because of its previous use in water quality studies. The geo...

  11. Light Meson Distribution Amplitudes

    CERN Document Server

    Arthur, R; Brommel, D; Donnellan, M A; Flynn, J M; Juttner, A; de Lima, H Pedroso; Rae, T D; Sachrajda, C T; Samways, B

    2010-01-01

    We calculated the first two moments of the light-cone distribution amplitudes for the pseudoscalar mesons ($\\pi$ and $K$) and the longitudinally polarised vector mesons ($\\rho$, $K^*$ and $\\phi$) as part of the UKQCD and RBC collaborations' $N_f=2+1$ domain-wall fermion phenomenology programme. These quantities were obtained with a good precision and, in particular, the expected effects of $SU(3)$-flavour symmetry breaking were observed. Operators were renormalised non-perturbatively and extrapolations to the physical point were made, guided by leading order chiral perturbation theory. The main results presented are for two volumes, $16^3\\times 32$ and $24^3\\times 64$, with a common lattice spacing. Preliminary results for a lattice with a finer lattice spacing, $32^3\\times64$, are discussed and a first look is taken at the use of twisted boundary conditions to extract distribution amplitudes.

  12. Agile & Distributed Project Management

    DEFF Research Database (Denmark)

    Pries-Heje, Jan; Pries-Heje, Lene

    2011-01-01

    Scrum has gained surprising momentum as an agile IS project management approach. An obvious question is why Scrum is so useful? To answer that question we carried out a longitudinal study of a distributed project using Scrum. We analyzed the data using coding and categorisation and three carefully...... selected theoretical frameworks. Our conclusion in this paper is that Scrum is so useful because it provides effective communication in the form of boundary objects and boundary spanners, it provides effective social integration by building up social team capital, and it provides much needed control and...... coordination mechanisms by allowing both local and global articulation of work in the project. That is why Scrum is especially useful for distributed IS project management and teamwork....

  13. Distribution load estimation (DLE)

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A.; Lehtonen, M. [VTT Energy, Espoo (Finland)

    1998-08-01

    The load research has produced customer class load models to convert the customers` annual energy consumption to hourly load values. The reliability of load models applied from a nation-wide sample is limited in any specific network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to find improvements to the load models or, in general, improvements to the load estimates. In Distribution Load Estimation (DLE) the measurements from the network are utilized to improve the customer class load models. The results of DLE will be new load models that better correspond to the loading of the distribution network but are still close to the original load models obtained by load research. The principal data flow of DLE is presented

  14. DIRAC distributed computing services

    International Nuclear Information System (INIS)

    DIRAC Project provides a general-purpose framework for building distributed computing systems. It is used now in several HEP and astrophysics experiments as well as for user communities in other scientific domains. There is a large interest from smaller user communities to have a simple tool like DIRAC for accessing grid and other types of distributed computing resources. However, small experiments cannot afford to install and maintain dedicated services. Therefore, several grid infrastructure projects are providing DIRAC services for their respective user communities. These services are used for user tutorials as well as to help porting the applications to the grid for a practical day-to-day work. The services are giving access typically to several grid infrastructures as well as to standalone computing clusters accessible by the target user communities. In the paper we will present the experience of running DIRAC services provided by the France-Grilles NGI and other national grid infrastructure projects.

  15. On Distribution Preserving Quantization

    CERN Document Server

    Li, Minyue; Kleijn, W Bastiaan

    2011-01-01

    Upon compressing perceptually relevant signals, conventional quantization generally results in unnatural outcomes at low rates. We propose distribution preserving quantization (DPQ) to solve this problem. DPQ is a new quantization concept that confines the probability space of the reconstruction to be identical to that of the source. A distinctive feature of DPQ is that it facilitates a seamless transition between signal synthesis and quantization. A theoretical analysis of DPQ leads to a distribution preserving rate-distortion function (DP-RDF), which serves as a lower bound on the rate of any DPQ scheme, under a constraint on distortion. In general situations, the DP-RDF approaches the classic rate-distortion function for the same source and distortion measure, in the limit of an increasing rate. A practical DPQ scheme based on a multivariate transformation is also proposed. This scheme asymptotically achieves the DP-RDF for i.i.d. Gaussian sources and the mean squared error.

  16. Distributed multinomial regression

    OpenAIRE

    Taddy, Matt

    2015-01-01

    This article introduces a model-based approach to distributed computing for multinomial logistic (softmax) regression. We treat counts for each response category as independent Poisson regressions via plug-in estimates for fixed effects shared across categories. The work is driven by the high-dimensional-response multinomial models that are used in analysis of a large number of random counts. Our motivating applications are in text analysis, where documents are tokenized and the token counts ...

  17. Contracts in distributed systems

    OpenAIRE

    Massimo Bartoletti; Emilio Tuosto; Roberto Zunino

    2011-01-01

    We present a parametric calculus for contract-based computing in distributed systems. By abstracting from the actual contract language, our calculus generalises both the contracts-as-processes and contracts-as-formulae paradigms. The calculus features primitives for advertising contracts, for reaching agreements, and for querying the fulfilment of contracts. Coordination among principals happens via multi-party sessions, which are created once agreements are reached. We present two instances ...

  18. Liquidity, Welfare and Distribution

    OpenAIRE

    Martín Gil Samuel

    2012-01-01

    This work presents a dynamic general equilibrium model where wealth distribution is endogenous. I provide channels of causality that suggest a complex relationship between financial markets and the real activity which breaks down the classical dichotomy. As a consequence, the Friedman rule does not hold. In terms of the current events taking place in the world economy, this paper provides a rationale to advert against the perils of an economy satiated with liquidity. Efficiency and dist...

  19. Optimal distributed dynamic advertising

    OpenAIRE

    Marinelli, Carlo; Savin, Sergei

    2004-01-01

    We propose a novel approach to modeling advertising dynamics for a firm operating over distributed market domain based on controlled partial differential equations of diffusion type. Using our model, we consider a general type of finite-horizon profit maximization problem in a monopoly setting. By reformulating this profit maximization problem as an optimal control problem in infinite dimensions, we derive sufficient conditions for the existence of its optimal solutions under general profit f...

  20. Fission fragment angular distributions

    International Nuclear Information System (INIS)

    Recently a Letter appeared (Phys. Rev. Lett., 522, 414(1984)) claiming that the usual expression for describing the angula distribution of fission fragments from compound nuclear decay is not a necessarily valid limit of a more general expression. In this comment we wish to point out that the two expressions arise from distinctly different models, and that the new expression as used in the cited reference is internally inconsistent

  1. Distributed Authorization in Vanadium

    OpenAIRE

    Taly, Ankur; Shankar, Asim

    2016-01-01

    In this tutorial, we present an authorization model for distributed systems that operate with limited internet connectivity. Reliable internet access remains a luxury for a majority of the world's population. Even for those who can afford it, a dependence on internet connectivity may lead to sub-optimal user experiences. With a focus on decentralized deployment, we present an authorization model that is suitable for scenarios where devices right next to each other (such as a sensor or a frien...

  2. Air Distribution in Rooms

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    The research on air distribution in rooms is often done as full-size investigations, scale-model investigations or by Computational Fluid Dynamics (CFD). New activities have taken place within all three areas and this paper draws comparisons between the different methods. The outcome of the l......EA sponsored research "Air Flow Pattern within Buildings" is used for comparisons in some parts of the paper because various types of experiments and many countries are involved....

  3. Learning transformed product distributions

    OpenAIRE

    Daskalakis, Constantinos; Diakonikolas, Ilias; Servedio, Rocco A.

    2011-01-01

    We consider the problem of learning an unknown product distribution $X$ over $\\{0,1\\}^n$ using samples $f(X)$ where $f$ is a \\emph{known} transformation function. Each choice of a transformation function $f$ specifies a learning problem in this framework. Information-theoretic arguments show that for every transformation function $f$ the corresponding learning problem can be solved to accuracy $\\eps$, using $\\tilde{O}(n/\\eps^2)$ examples, by a generic algorithm whose running time may be expon...

  4. Electric power distribution reliability

    CERN Document Server

    Brown, Richard E

    2002-01-01

    Balancing theory, practical knowledge, and real-world applications, this reference consolidates all pertinent topics related to power distribution reliability into one comprehensive volume. Exploring pressing issues in creating and analyzing reliability models, the author highlights the most effective techniques to achieve maximum performance at lowest cost. With over 300 tables, figures, and equations, the book discusses service interruptions caused by equipment malfunction, animals, trees, severe weather, natural disasters, and human error and evaluates strategies to improve reliability and

  5. Quantum Message Distribution

    Institute of Scientific and Technical Information of China (English)

    LUO Ming-Xing; CHEN Xiu-Bo; DENG Yun; Yang Yi-Xian

    2013-01-01

    The semiquantum techniques have been explored recently to bridge the classical communications and the quantum communications.In this paper,we present one scheme to distribute the messages from one quantum participate to one weak quantum participate who can only measure the quantum states.It is proved to be robust by combining the classical coding encryption,quantum coding and other quantum techniques.

  6. The generalized distributive law

    OpenAIRE

    Aji, Srinivas M.; McEliece, Robert J.

    2000-01-01

    We discuss a general message passing algorithm, which we call the generalized distributive law (GDL). The GDL is a synthesis of the work of many authors in information theory, digital communications, signal processing, statistics, and artificial intelligence. It includes as special cases the Baum-Welch algorithm, the fast Fourier transform (FFT) on any finite Abelian group, the Gallager-Tanner-Wiberg decoding algorithm, Viterbi's algorithm, the BCJR algorithm, Pearl's “belief propagation” alg...

  7. Distributed Computing Economics

    OpenAIRE

    Gray, Jim

    2004-01-01

    Computing economics are changing. Today there is rough price parity between (1) one database access, (2) ten bytes of network traffic, (3) 100,000 instructions, (4) 10 bytes of disk storage, and (5) a megabyte of disk bandwidth. This has implications for how one structures Internet-scale distributed computing: one puts computing as close to the data as possible in order to avoid expensive network traffic.

  8. Protection in Distributed Generation

    OpenAIRE

    Comech, M.Paz; Garcia-Gracia, Miguel; Borroy, Samuel; Villen, M.Teresa

    2010-01-01

    The expectable great penetration of dispersed generators in distribution systems can lead to conflicts with the current protection schemes, since they were designed to work in a different scenario and under different conditions. Most of the problems described in this chapter would be solved with the implementation of communication schemes and providing the power system with some "intelligence". In this line, the standard IEC61850 and new developments like Smart Grids are expected to bring new...

  9. Distributed Priority Synthesis

    Directory of Open Access Journals (Sweden)

    Harald Ruess

    2012-11-01

    Full Text Available Given a set of interacting components with non-deterministic variable update and given safety requirements, the goal of priority synthesis is to restrict, by means of priorities, the set of possible interactions in such a way as to guarantee the given safety conditions for all possible runs. In distributed priority synthesis we are interested in obtaining local sets of priorities, which are deployed in terms of local component controllers sharing intended next moves between components in local neighborhoods only. These possible communication paths between local controllers are specified by means of a communication architecture. We formally define the problem of distributed priority synthesis in terms of a multi-player safety game between players for (angelically selecting the next transition of the components and an environment for (demonically updating uncontrollable variables. We analyze the complexity of the problem, and propose several optimizations including a solution-space exploration based on a diagnosis method using a nested extension of the usual attractor computation in games together with a reduction to corresponding SAT problems. When diagnosis fails, the method proposes potential candidates to guide the exploration. These optimized algorithms for solving distributed priority synthesis problems have been integrated into the VissBIP framework. An experimental validation of this implementation is performed using a range of case studies including scheduling in multicore processors and modular robotics.

  10. A distribution management system

    Energy Technology Data Exchange (ETDEWEB)

    Verho, P.; Jaerventausta, P.; Kaerenlampi, M.; Paulasaari, H. [Tampere Univ. of Technology (Finland); Partanen, J. [Lappeenranta Univ. of Technology (Finland)

    1996-12-31

    The development of new distribution automation applications is considerably wide nowadays. One of the most interesting areas is the development of a distribution management system (DMS) as an expansion of the traditional SCADA system. At the power transmission level such a system is called an energy management system (EMS). The idea of these expansions is to provide supporting tools for control center operators in system analysis and operation planning. The needed data for new applications is mainly available in some existing systems. Thus the computer systems of utilities must be integrated. The main data source for the new applications in the control center are the AM/FM/GIS (i.e. the network database system), the SCADA, and the customer information system (CIS). The new functions can be embedded in some existing computer system. This means a strong dependency on the vendor of the existing system. An alternative strategy is to develop an independent system which is integrated with other computer systems using well-defined interfaces. The latter approach makes it possible to use the new applications in various computer environments, having only a weak dependency on the vendors of the other systems. In the research project this alternative is preferred and used in developing an independent distribution management system

  11. Multivariate Matrix-Exponential Distributions

    DEFF Research Database (Denmark)

    Bladt, Mogens; Nielsen, Bo Friis

    2010-01-01

    In this article we consider the distributions of non-negative random vectors with a joint rational Laplace transform, i.e., a fraction between two multi-dimensional polynomials. These distributions are in the univariate case known as matrix-exponential distributions, since their densities can be...... written as linear combinations of the elements in the exponential of a matrix. For this reason we shall refer to multivariate distributions with rational Laplace transform as multivariate matrix-exponential distributions (MVME). The marginal distributions of an MVME are univariate matrix......-exponential distributions. We prove a characterization that states that a distribution is an MVME distribution if and only if all non-negative, non-null linear combinations of the coordinates have a univariate matrix-exponential distribution. This theorem is analog to a well-known characterization theorem for the...

  12. GASIFICATION FOR DISTRIBUTED GENERATION

    Energy Technology Data Exchange (ETDEWEB)

    Ronald C. Timpe; Michael D. Mann; Darren D. Schmidt

    2000-05-01

    A recent emphasis in gasification technology development has been directed toward reduced-scale gasifier systems for distributed generation at remote sites. The domestic distributed power generation market over the next decade is expected to be 5-6 gigawatts per year. The global increase is expected at 20 gigawatts over the next decade. The economics of gasification for distributed power generation are significantly improved when fuel transport is minimized. Until recently, gasification technology has been synonymous with coal conversion. Presently, however, interest centers on providing clean-burning fuel to remote sites that are not necessarily near coal supplies but have sufficient alternative carbonaceous material to feed a small gasifier. Gasifiers up to 50 MW are of current interest, with emphasis on those of 5-MW generating capacity. Internal combustion engines offer a more robust system for utilizing the fuel gas, while fuel cells and microturbines offer higher electric conversion efficiencies. The initial focus of this multiyear effort was on internal combustion engines and microturbines as more realistic near-term options for distributed generation. In this project, we studied emerging gasification technologies that can provide gas from regionally available feedstock as fuel to power generators under 30 MW in a distributed generation setting. Larger-scale gasification, primarily coal-fed, has been used commercially for more than 50 years to produce clean synthesis gas for the refining, chemical, and power industries. Commercial-scale gasification activities are under way at 113 sites in 22 countries in North and South America, Europe, Asia, Africa, and Australia, according to the Gasification Technologies Council. Gasification studies were carried out on alfalfa, black liquor (a high-sodium waste from the pulp industry), cow manure, and willow on the laboratory scale and on alfalfa, black liquor, and willow on the bench scale. Initial parametric tests

  13. THE DISTRIBUTIONAL DIMENSION OF FRACTALS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In the book [1] H.Triebel introduces the distributional dimension of fractals in and distributional dimension, respectively. Thus we might say that the distributional dimension is an analytical definition for Hausdorff dimension. Therefore we can study Hausdorff dimension through the distributional dimension analytically.By discussing the distributional dimension, this paper intends to set up a criterion for estimating the upper and lower bounds of Hausdorff dimension analytically. Examples illustrating the criterion are included in the end.

  14. A new Markov Binomial distribution.

    OpenAIRE

    Omey, Edward; Minkova, Leda D.

    2011-01-01

    In this paper, we introduce a two state homogeneous Markov chain and define a geometric distribution related to this Markov chain. We define also the negative binomial distribution similar to the classical case and call it NB related to interrupted Markov chain. The new binomial distribution is related to the interrupted Markov chain. Some characterization properties of the Geometric distributions are given. Recursion formulas and probability mass functions for the NB distribution and the new...

  15. Optimizing queries in distributed systems

    Directory of Open Access Journals (Sweden)

    Ion LUNGU

    2006-01-01

    Full Text Available This research presents the main elements of query optimizations in distributed systems. First, data architecture according with system level architecture in a distributed environment is presented. Then the architecture of a distributed database management system (DDBMS is described on conceptual level followed by the presentation of the distributed query execution steps on these information systems. The research ends with presentation of some aspects of distributed database query optimization and strategies used for that.

  16. Density Distribution Sunflower Plots

    OpenAIRE

    Dupont, William D.; W. Dale Plummer Jr.

    2003-01-01

    Density distribution sunflower plots are used to display high-density bivariate data. They are useful for data where a conventional scatter plot is difficult to read due to overstriking of the plot symbol. The x-y plane is subdivided into a lattice of regular hexagonal bins of width w specified by the user. The user also specifies the values of l, d, and k that affect the plot as follows. Individual observations are plotted when there are less than l observations per bin as in a conventio...

  17. Distributed multiple description coding

    CERN Document Server

    Bai, Huihui; Zhao, Yao

    2011-01-01

    This book examines distributed video coding (DVC) and multiple description coding (MDC), two novel techniques designed to address the problems of conventional image and video compression coding. Covering all fundamental concepts and core technologies, the chapters can also be read as independent and self-sufficient, describing each methodology in sufficient detail to enable readers to repeat the corresponding experiments easily. Topics and features: provides a broad overview of DVC and MDC, from the basic principles to the latest research; covers sub-sampling based MDC, quantization based MDC,

  18. Distributed actuator deformable mirror

    CERN Document Server

    Bonora, Stefano

    2010-01-01

    In this paper we present a Deformable Mirror (DM) based on the continuous voltage distribution over a resistive layer. This DM can correct the low order aberrations (defocus, astigmatism, coma and spherical aberration) using three electrodes with nine contacts leading to an ideal device for sensorless applications. We present a mathematical description of the mirror, a comparison between the simulations and the experimental results. In order to demonstrate the effectiveness of the device we compared its performance with the one of a multiactuator DM of similar properties in the correction of an aberration statistics. At the end of the paper an example of sensorless correction is shown.

  19. On Distributed Embedded Systems

    Directory of Open Access Journals (Sweden)

    Arvindra Sehmi

    2013-01-01

    Full Text Available Thinking of distributed embedded systems (DES—let alone the more general area of embedded computing—as a unified topic is difficult. Nevertheless, it is a vastly important topic and potentially represents a revolution in information technology (IT. DES is driven by the increasing capabilities and ever-declining costs of computing and communications devices, resulting in networked systems of embedded computers whose functional components are nearly invisible to end users. Systems have the potential to alter radically the way in which people interact with their environment by linking a range of devices and sensors that will allow information to be collected, shared, and processed in unprecedented ways.

  20. DEM - distribution energy management

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A.; Kekkonen, V.; Koreneff, G. [VTT Energy, Espoo (Finland)] [and others

    1998-08-01

    The electricity market was de-regulated in Finland at the end of 1995 and the customers can now freely choose their power suppliers. The national grid and local distribution network operators are now separated from the energy business. The network operators transmit the electric power to the customers on equal terms regardless from whom the power is purchased. The Finnish national grid is owned by one company Finnish Power Grid PLC (Fingrid). The major shareholders of Fingrid are the state of Finland, two major power companies and institutional investors. In addition there are about 100 local distribution utilities operating the local 110 kV, 20 kV and 0.4 kV networks. The distribution utilities are mostly owned by the municipalities and towns. In each network one energy supplier is always responsible for the hourly energy balance in the network (a `host`) and it also has the obligation to provide public energy prices accessible to any customer in the network`s area. The Finnish regulating authorities nominate such a supplier who has a dominant market share in the network`s area as the supplier responsible for the network`s energy balance. A regulating authority, called the Electricity Market Centre, ensures that the market is operating properly. The transmission prices and public energy prices are under the Electricity Market Centre`s control. For domestic and other small customers the cost of hourly metering (ca. 1000 US$) would be prohibitive and therefore the use of conventional energy metering and load models is under consideration by the authorities. Small customer trade with the load models (instead of the hourly energy recording) is scheduled to start in the first half of 1998. In this presentation, the problems of energy management from the standpoint of the energy trading and distributing companies in the new situation are first discussed. The topics covered are: the hourly load data management, the forecasting and estimation of hourly energy demands

  1. Approximation of distributed delays

    CERN Document Server

    Lu, Hao; Eberard, Damien; Simon, Jean-Pierre

    2010-01-01

    We address in this paper the approximation problem of distributed delays. Such elements are convolution operators with kernel having bounded support, and appear in the control of time-delay systems. From the rich literature on this topic, we propose a general methodology to achieve such an approximation. For this, we enclose the approximation problem in the graph topology, and work with the norm defined over the convolution Banach algebra. The class of rational approximates is described, and a constructive approximation is proposed. Analysis in time and frequency domains is provided. This methodology is illustrated on the stabilization control problem, for which simulations results show the effectiveness of the proposed methodology.

  2. Distribution load estimation - DLE

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A. [VTT Energy, Espoo (Finland)

    1996-12-31

    The load research project has produced statistical information in the form of load models to convert the figures of annual energy consumption to hourly load values. The reliability of load models is limited to a certain network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to make improvements in the load models. Distribution load estimation (DLE) is the method developed here to improve load estimates from the load models. The method is also quite cheap to apply as it utilises information that is already available in SCADA systems

  3. Distributed Parameter Modelling Applications

    DEFF Research Database (Denmark)

    Sales-Cruz, Mauricio; Cameron, Ian; Gani, Rafiqul

    development of a short-path evaporator. The oil shale processing problem illustrates the interplay amongst particle flows in rotating drums, heat and mass transfer between solid and gas phases. The industrial application considers the dynamics of an Alberta-Taciuk processor, commonly used in shale oil and oil......Here the issue of distributed parameter models is addressed. Spatial variations as well as time are considered important. Several applications for both steady state and dynamic applications are given. These relate to the processing of oil shale, the granulation of industrial fertilizers and the...

  4. Contracts in distributed systems

    CERN Document Server

    Bartoletti, Massimo; Zunino, Roberto; 10.4204/EPTCS.59.11

    2011-01-01

    We present a parametric calculus for contract-based computing in distributed systems. By abstracting from the actual contract language, our calculus generalises both the contracts-as-processes and contracts-as-formulae paradigms. The calculus features primitives for advertising contracts, for reaching agreements, and for querying the fulfilment of contracts. Coordination among principals happens via multi-party sessions, which are created once agreements are reached. We present two instances of our calculus, by modelling contracts as (i) processes in a variant of CCS, and (ii) as formulae in a logic. With the help of a few examples, we discuss the primitives of our calculus, as well as some possible variants.

  5. Bilateral matrix-exponential distributions

    DEFF Research Database (Denmark)

    Bladt, Mogens; Esparza, Luz Judith R; Nielsen, Bo Friis

    2012-01-01

    In this article we define the classes of bilateral and multivariate bilateral matrix-exponential distributions. These distributions have support on the entire real space and have rational moment-generating functions. These distributions extend the class of bilateral phasetype distributions of [1......] and the class of multivariate matrix-exponential distributions of [9]. We prove a characterization theorem stating that a random variable has a bilateral multivariate distribution if and only if all linear combinations of the coordinates have a univariate bilateral matrix-exponential distribution. As...... an application we demonstrate that certain multivariate disions, which are governed by the underlying Markov jump process generating a phasetype distribution, have a bilateral matrix-exponential distribution at the time of absorption, see also [4]....

  6. FMCG companies specific distribution channels

    Directory of Open Access Journals (Sweden)

    Ioana Barin

    2009-12-01

    Full Text Available Distribution includes all activities undertaken by the producer, alone or in cooperation, since the end of the final finished products or services until they are in possession of consumers. The distribution consists of the following major components: distribution channels or marketing channels, which together form a distribution network; logistics o rphysical distribution. In order to effective achieve, distribution of goods requires an amount of activities and operational processes related to transit of goods from producer to consumer, the best conditions, using existing distribution channels and logistics system. One of the essential functions of a distribution is performing acts of sale, through which, with the actual movement of goods, their change of ownership takes place, that the successive transfer of ownership from producer to consumer. This is an itinerary in the economic cycle of goods, called the distribution channel.

  7. SYVAC3 parameter distribution package

    International Nuclear Information System (INIS)

    SYVAC3 (Systems Variability Analysis Code, generation 3) is a computer program that implements a method called systems variability analysis to analyze the behaviour of a system in the presence of uncertainty. This method is based on simulating the system many times to determine the variation in behaviour it can exhibit. SYVAC3 specializes in systems representing the transport of contaminants, and has several features to simplify the modelling of such systems. It provides a general tool for estimating environmental impacts from the dispersal of contaminants. This report describes a software object type (a generalization of a data type) called Parameter Distribution. This object type is used in SYVAC3, and can also be used independently. Parameter Distribution has the following subtypes: beta distribution; binomial distribution; constant distribution; lognormal distribution; loguniform distribution; normal distribution; piecewise uniform distribution; Triangular distribution; and uniform distribution. Some of these distributions can be altered by correlating two parameter distribution objects. This report provides complete specifications for parameter distributions, and also explains how to use them. It should meet the needs of casual users, reviewers, and programmers who wish to add their own subtypes. (author). 30 refs., 75 tabs., 56 figs

  8. High Level Ultra Low Power Transmitters for the MICS Standard

    OpenAIRE

    Eidenvall, Per; Gran, Nils

    2010-01-01

    Today, medical implants such as cardiac pacemakers, neurostimulators, hearing aids anddrug delivery systems are increasinglymore important and frequently used in the health caresystem. This type of devices have historically used inductive coupling as communicationmedium. Newdemands on accessibility and increased performance in technology drives newresearch toward using radio communications. The FCCMICS radio standard are specificallydevoted for implantable devices.Basically all published resea...

  9. Estudi aerodinàmic d’un bobsleigh

    OpenAIRE

    Saguer i Parra, Sergi

    2004-01-01

    L’objectiu d’aquest projecte és partir d’una configuració actual d’un bobsleigh que compleixi la normativa vigent i assolir una configuració que presenti una resistència a l’avanç inferior a l’original i aporti un major nivell de seguretat als ocupants. El flux que seguirà el desenvolupament del projecte serà el següent: • Disseny mitjançant SolidWorks dels models inicials i de les possibles solucions. • Estudi teòric amb eines de flux potencial dels models proposats. • Estu...

  10. Open mic: Introduction to the CERN Study Group

    CERN Document Server

    CERN. Geneva

    2016-01-01

    Mozilla Study Groups are knowledge- and skill-sharing meet-ups for people to get help with their research or work on open-science projects. A CERN chapter was launched recently and you are invited to participate!

  11. Microbiologically influenced corrosion (MIC) of storage tank bottom plates

    Science.gov (United States)

    Syafaat, Taufik A.; Ismail, Mokhtar Che

    2015-07-01

    Aboveground atmospheric storage tanks (AST) receive crude oil from offshore for storage and further processing. Integrity issue of AST storing crude oil is not only affected by external corrosion but also internal corrosion from crude oil that supports the growth of the microorganisms originating from the reservoir. The objective of this research is to study the effect of sulfate reduction bacteria (SRB) on the corrosion of AST. The results indicates that SRB has significant effect on the corrosion rate of storage tank bottom plate.

  12. Gradient Plate for Hicomb Minimum Inhibitory Concentration (MIC) Test

    OpenAIRE

    Fatemi Motlagh M; Varham H; Mansori N

    2011-01-01

    Bakground and objectives: "The comb antibiotic sensitivity test" is a quick,reliable and cost effective method to determine the susceptibility of bacteriato different antibiotics. The purpose of this study is to design a plate that iseasy and quick to use, and enable to be interpreted easily without the need formeasurement of the margins with a ruler.Material and Methods: First, Clinical and Laboratory Standards Institutedata about the maximum growth inhibitory haloes formed with antibioticsa...

  13. Pelasgos y Micénicos en Tesalia

    OpenAIRE

    García Ramón, J. L.

    2009-01-01

    Hay en las primeras etapas de la historia de Grecia una serie de problemas de todo tipo para cuya solución los testimonios de los autores antiguos no sólo no han sido de excesiva utilidad, sino que más bien han contribuido a complicar que a explicar las cosas. Baste recordar en este sentido el difuso significado que en la tradición antigua tiene el término «eolio», auténtico cajón de sastre en el que entraba toda estirpe o dialecto griego no clasificable como jonio, ático o dorio; la fidelida...

  14. RapidMic: Rapid Computation of the Maximal Information Coefficient

    OpenAIRE

    Dongming Tang; Mingwen Wang; Weifan Zheng; Hongjun Wang

    2014-01-01

    To discover relationships and associations rapidly in large-scale datasets, we propose a cross-platform tool for the rapid computation of the maximal information coefficient based on parallel computing methods. Through parallel processing, the provided tool can effectively analyze large-scale biological datasets with a markedly reduced computing time. The experimental results show that the proposed tool is notably fast, and is able to perform an all-pairs analysis of a large biological datase...

  15. MIC polar discriminators and multifunction modules in EW systems

    Science.gov (United States)

    Chelli, R.; Gasperini, S.; Quaglia, A.

    In the design of modern airborne and shipborne electronic warfare (EW) systems, problems arise with respect to weight, size, cost and repeatability demands. The approaches used to obtain solutions to those problems frequently involve the use of new structures, based on the development of integrated microwave subsystem and multifunction modules. The two most useful configurations are related to strip-line and microstrip designs. A Polar Frequency Discriminator (PFD) is a subsystem which relates its output angle with an input frequency. This subsystem includes a power splitter, a delay line, and a Polar Phase Discriminator (PPD) with four detectors. A PPD which includes three 3-dB hybrid couplers, and a power splitter is considered. Attention is given to the development of suitable PFDs, and the design of a mcirostrip broadband multifunction component. The component is used for a Built-In Test Equipment (BITE) in a ship-borne system.

  16. MIC Leak Disaster and Environmental Contamination: Time to Act Now

    Directory of Open Access Journals (Sweden)

    Brajendra Mishra, Nalok Banerjee

    2014-01-01

    Conclusion: Fear of contamination and resultant ill health is so far un-substantiated. However, further study should be conducted to link toxicant present in water/soil, pathways to reach food chain and ultimately human body and with their present health status. Soil remediation should be under taken on war footing.

  17. Coping with distributed computing

    International Nuclear Information System (INIS)

    The rapid increase in the availability of high performance, cost-effective RISC/UNIX workstations has been both a blessing and a curse. The blessing of having extremely powerful computing engines available on the desk top is well-known to many users. The user has tremendous freedom, flexibility, and control of his environment. That freedom can, however, become the curse of distributed computing. The user must become a system manager to some extent, he must worry about backups, maintenance, upgrades, etc. Traditionally these activities have been the responsibility of a central computing group. The central computing group, however, may find that it can no longer provide all of the traditional services. With the plethora of workstations now found on so many desktops throughout the entire campus or lab, the central computing group may be swamped by support requests. This talk will address several of these computer support and management issues by providing some examples of the approaches taken at various HEP institutions. In addition, a brief review of commercial directions or products for distributed computing and management will be given

  18. Testing reveals proppant distribution

    Energy Technology Data Exchange (ETDEWEB)

    Crump, J.B. (Halliburton Services, Duncan, OK (US)); Ekstrand, B.B. (Halliburton Services, Houston, TX (US)); Almond, S.W. (Halliburton Services, Bakersfield, CA (US))

    1988-10-31

    Sand distribution tests, undertaken to answer inquiries from a producing company, have shown that proppant placed during a hydraulic fracture treatment is evenly distributed into the perforated interval. Therefore, for planning purposes, a good assumption is that all perforations will pass essentially equal volumes of proppant, provided perforation quality is uniform, perforations are open, and bottom hole treating pressure is constant across the interval. Under simulated conditions, a fluid viscosity of 30 cp (511 sec/sup -1/) allowed 20/40 sand to ''turn to corner'' and pass through perforations with minimal stratification. This finding refutes the theory held by some that the bottom perforation is ''slugged'' with heavier concentration of sand than the upper perforations, and the theory's logical extension that after the bottom perforation is filled, it plugs and the perforation just above becomes the next bottom until the entire perforated interval is screened out. Tests described in this article were part of a program implemented to analyze causes of screen outs encountered in fracturing operations.

  19. Distributed System Design Checklist

    Science.gov (United States)

    Hall, Brendan; Driscoll, Kevin

    2014-01-01

    This report describes a design checklist targeted to fault-tolerant distributed electronic systems. Many of the questions and discussions in this checklist may be generally applicable to the development of any safety-critical system. However, the primary focus of this report covers the issues relating to distributed electronic system design. The questions that comprise this design checklist were created with the intent to stimulate system designers' thought processes in a way that hopefully helps them to establish a broader perspective from which they can assess the system's dependability and fault-tolerance mechanisms. While best effort was expended to make this checklist as comprehensive as possible, it is not (and cannot be) complete. Instead, we expect that this list of questions and the associated rationale for the questions will continue to evolve as lessons are learned and further knowledge is established. In this regard, it is our intent to post the questions of this checklist on a suitable public web-forum, such as the NASA DASHLink AFCS repository. From there, we hope that it can be updated, extended, and maintained after our initial research has been completed.

  20. Atlas Distributed Analysis Tools

    Science.gov (United States)

    de La Hoz, Santiago Gonzalez; Ruiz, Luis March; Liko, Dietrich

    2008-06-01

    The ATLAS production system has been successfully used to run production of simulation data at an unprecedented scale. Up to 10000 jobs were processed in one day. The experiences obtained operating the system on several grid flavours was essential to perform a user analysis using grid resources. First tests of the distributed analysis system were then performed. In the preparation phase data was registered in the LHC File Catalog (LFC) and replicated in external sites. For the main test, few resources were used. All these tests are only a first step towards the validation of the computing model. The ATLAS management computing board decided to integrate the collaboration efforts in distributed analysis in only one project, GANGA. The goal is to test the reconstruction and analysis software in a large scale Data production using Grid flavors in several sites. GANGA allows trivial switching between running test jobs on a local batch system and running large-scale analyses on the Grid; it provides job splitting and merging, and includes automated job monitoring and output retrieval.

  1. ATLAS Distributed Analysis Tools

    CERN Document Server

    Gonzalez de la Hoz, Santiago; Liko, Dietrich

    2008-01-01

    The ATLAS production system has been successfully used to run production of simulation data at an unprecedented scale. Up to 10000 jobs were processed in one day. The experiences obtained operating the system on several grid flavours was essential to perform a user analysis using grid resources. First tests of the distributed analysis system were then performed. In the preparation phase data was registered in the LHC File Catalog (LFC) and replicated in external sites. For the main test, few resources were used. All these tests are only a first step towards the validation of the computing model. The ATLAS management computing board decided to integrate the collaboration efforts in distributed analysis in only one project, GANGA. The goal is to test the reconstruction and analysis software in a large scale Data production using Grid flavors in several sites. GANGA allows trivial switching between running test jobs on a local batch system and running large-scale analyses on the Grid; it provides job splitting a...

  2. Bounding species distribution models

    Institute of Scientific and Technical Information of China (English)

    Thomas J. STOHLGREN; Catherine S. JARNEVICH; Wayne E. ESAIAS; Jeffrey T. MORISETTE

    2011-01-01

    Species distribution models are increasing in popularity for mapping suitable habitat for species of management concern.Many investigators now recognize that extrapolations of these models with geographic information systems (GIS) might be sensitive to the environmental bounds of the data used in their development,yet there is no recommended best practice for “clamping” model extrapolations.We relied on two commonly used modeling approaches:classification and regression tree (CART) and maximum entropy (Maxent) models,and we tested a simple alteration of the model extrapolations,bounding extrapolations to the maximum and minimum values of primary environmental predictors,to provide a more realistic map of suitable habitat of hybridized Africanized honey bees in the southwestern United States.Findings suggest that multiple models of bounding,and the most conservative bounding of species distribution models,like those presented here,should probably replace the unbounded or loosely bounded techniques currently used [Current Zoology 57 (5):642-647,2011].

  3. Efficient Distributed Medium Access

    CERN Document Server

    Shah, Devavrat; Tetali, Prasad

    2011-01-01

    Consider a wireless network of n nodes represented by a graph G=(V, E) where an edge (i,j) models the fact that transmissions of i and j interfere with each other, i.e. simultaneous transmissions of i and j become unsuccessful. Hence it is required that at each time instance a set of non-interfering nodes (corresponding to an independent set in G) access the wireless medium. To utilize wireless resources efficiently, it is required to arbitrate the access of medium among interfering nodes properly. Moreover, to be of practical use, such a mechanism is required to be totally distributed as well as simple. As the main result of this paper, we provide such a medium access algorithm. It is randomized, totally distributed and simple: each node attempts to access medium at each time with probability that is a function of its local information. We establish efficiency of the algorithm by showing that the corresponding network Markov chain is positive recurrent as long as the demand imposed on the network can be supp...

  4. Optimizing electrical distribution systems

    International Nuclear Information System (INIS)

    Electrical utility distribution systems are in the middle of an unprecedented technological revolution in planning, design, maintenance and operation. The prime movers of the revolution are the major economic shifts that affect decision making. The major economic influence on the revolution is the cost of losses (technical and nontechnical). The vehicle of the revolution is the computer, which enables decision makers to examine alternatives in greater depth and detail than their predecessors could. The more important elements of the technological revolution are: system planning, computers, load forecasting, analytical systems (primary systems, transformers and secondary systems), system losses and coming technology. The paper is directed towards the rather unique problems encountered by engineers of utilities in developing countries - problems that are being solved through high technology, such as the recent World Bank-financed engineering computer system for Sri Lanka. This system includes a DEC computer, digitizer, plotter and engineering software to model the distribution system via a digitizer, analyse the system and plot single-line diagrams. (author). 1 ref., 4 tabs., 6 figs

  5. Power distribution measuring device

    International Nuclear Information System (INIS)

    The present invention concerns a device for measuring power distribution of neutrons in a nuclear reactor. That is, a gamma thermometer used so far has drawbacks of slow time response and low sensitivity although it is not always necessary to use a movable incore detector for calibration. However, the device of the present invention compensates the drawback by incorporating a gamma thermometer and an another incore detector of a different type in an identical detector assembly. The gamma thermometer is calibrated by an electric heater. With such a constitution, the sensitivity calibration of the detector of different type incorporated in the identical detector assembly can be conducted without relying on a movable detector when the reactor is stable. Further, if the detector of the different type having rapid response, such as a fission ionization chamber or a self-powered type detector is used as a detector, a reactor core power distribution monitoring system of rapid time response can be attained. (I.S.)

  6. Unintegrated parton distributions

    CERN Document Server

    Kimber, M

    2001-01-01

    We develop the theory of parton distributions f sub a (x, k sub t sup 2 , mu sup 2), unintegrated with respect to transverse momentum k sub t , from a phenomenological standpoint. In particular, we demonstrate a convenient approximation in which the unintegrated functions are obtained by explicitly performing the last step of parton evolution in perturbative QCD, with single-scale functions a(x,Q sup 2) as input. Results are presented in the context of DGLAP and combined BFKL-DGLAP evolution, but with angular ordering imposed in the last step of the evolution. We illustrate the application of these unintegrated distributions to predict cross sections for physical processes at lepton-hadron and hadron-hadron colliders. The use of partons with incoming transverse momentum, based on k sub t -factorisation, is intended to replace phenomenological 'smearing' in the perturbative region k sub t > k sub 0 (k sub 0 approx = 1 GeV), and enables the full kinematics of a process to be included even at leading order. We a...

  7. Parametrizing the exoplanet eccentricity distribution with the Beta distribution

    OpenAIRE

    Kipping, David M.

    2013-01-01

    It is suggested that the distribution of orbital eccentricities for extrasolar planets is well-described by the Beta distribution. Several properties of the Beta distribution make it a powerful tool for this purpose. For example, the Beta distribution can reproduce a diverse range of probability density functions (PDFs) using just two shape parameters (a and b). We argue that this makes it ideal for serving as a parametric model in Bayesian comparative population analysis. The Beta distributi...

  8. The double gluon distribution from the single gluon distribution

    CERN Document Server

    Golec-Biernat, Krzysztof; Serino, Mirko; Snyder, Zachary; Stasto, Anna

    2016-01-01

    Using momentum sum rule for evolution equations for Double Parton Distribution Functions (DPDFs) in the leading logarithmic approximation, we find that the double gluon distribution function can be uniquely constrained via the single gluon distribution function. We also study numerically its evolution with a hard scale and show that an approximately factorized ansatz into the product of two single gluon distributions performs quite well at small values of $x$ but is always violated for larger values, as expected.

  9. Loss Allocation in a Distribution System with Distributed Generation Units

    DEFF Research Database (Denmark)

    Lund, Torsten; Nielsen, Arne Hejde; Sørensen, Poul Ejnar

    2007-01-01

    In Denmark, a large part of the electricity is produced by wind turbines and combined heat and power plants (CHPs). Most of them are connected to the network through distribution systems. This paper presents a new algorithm for allocation of the losses in a distribution system with distributed...

  10. Distributed Wind Energy in Idaho

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, John [Boise State Univ., ID (United States); Johnson, Kathryn [Colorado School of Mines, Golden, CO (United States); Haynes, Todd [Boise State Univ., ID (United States); Seifert, Gary [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2009-01-31

    This project is a research and development program aimed at furthering distributed wind technology. In particular, this project addresses some of the barriers to distributed wind energy utilization in Idaho.

  11. Distributed mobility management - framework & analysis

    NARCIS (Netherlands)

    Liebsch, M.; Seite, P.; Karagiannis, G.

    2013-01-01

    Mobile operators consider the distribution of mobility anchors to enable offloading some traffic from their core network. The Distributed Mobility Management (DMM) Working Group is investigating the impact of decentralized mobility management to existing protocol solutions, while taking into account

  12. Distributed charging of electrical assets

    Science.gov (United States)

    Ghosh, Soumyadip; Phan, Dung; Sharma, Mayank; Wu, Chai Wah; Xiong, Jinjun

    2016-02-16

    The present disclosure relates generally to the field of distributed charging of electrical assets. In various examples, distributed charging of electrical assets may be implemented in the form of systems, methods and/or algorithms.

  13. Distributed Project Work

    DEFF Research Database (Denmark)

    Borch, Ole; Kirkegaard, B.; Knudsen, Morten;

    1998-01-01

    Project work has been used for many years at Aalborg University to improve learning of theory and methods given in courses. In a closed environment where the students are forming a group in a single room, the interaction behaviour is more or less given from the natural life. Group work...... in a distributed fashion over the Internet needs more attention to the interaction protocol since the physical group room is not existing. The purpose in this paper is to develop a method for online project work by using the product: Basic Support for Cooperative Work (BSCV). An analysis of a well-proven protocol...... for information exchange in the traditional project environment is performed. A group of teachers and a student group using small project examples test the method. The first test group used a prototype for testing and found the new activity synchronization difficult to adapt, so the method was finally adjusted...

  14. Contracts in distributed systems

    Directory of Open Access Journals (Sweden)

    Massimo Bartoletti

    2011-07-01

    Full Text Available We present a parametric calculus for contract-based computing in distributed systems. By abstracting from the actual contract language, our calculus generalises both the contracts-as-processes and contracts-as-formulae paradigms. The calculus features primitives for advertising contracts, for reaching agreements, and for querying the fulfilment of contracts. Coordination among principals happens via multi-party sessions, which are created once agreements are reached. We present two instances of our calculus, by modelling contracts as (i processes in a variant of CCS, and (ii as formulae in a logic. With the help of a few examples, we discuss the primitives of our calculus, as well as some possible variants.

  15. Process evaluation distributed system

    Science.gov (United States)

    Moffatt, Christopher L. (Inventor)

    2006-01-01

    The distributed system includes a database server, an administration module, a process evaluation module, and a data display module. The administration module is in communication with the database server for providing observation criteria information to the database server. The process evaluation module is in communication with the database server for obtaining the observation criteria information from the database server and collecting process data based on the observation criteria information. The process evaluation module utilizes a personal digital assistant (PDA). A data display module in communication with the database server, including a website for viewing collected process data in a desired metrics form, the data display module also for providing desired editing and modification of the collected process data. The connectivity established by the database server to the administration module, the process evaluation module, and the data display module, minimizes the requirement for manual input of the collected process data.

  16. Distributed road assessment system

    Science.gov (United States)

    Beer, N. Reginald; Paglieroni, David W

    2014-03-25

    A system that detects damage on or below the surface of a paved structure or pavement is provided. A distributed road assessment system includes road assessment pods and a road assessment server. Each road assessment pod includes a ground-penetrating radar antenna array and a detection system that detects road damage from the return signals as the vehicle on which the pod is mounted travels down a road. Each road assessment pod transmits to the road assessment server occurrence information describing each occurrence of road damage that is newly detected on a current scan of a road. The road assessment server maintains a road damage database of occurrence information describing the previously detected occurrences of road damage. After the road assessment server receives occurrence information for newly detected occurrences of road damage for a portion of a road, the road assessment server determines which newly detected occurrences correspond to which previously detected occurrences of road damage.

  17. Blood distribution measurements

    International Nuclear Information System (INIS)

    The necessity of employing a vascular exploration technique, which is non-aggressive and repetitive, and which gives total and quantitative results led to the exploitation of a rheo-graphic method. An apparatus was constructed for making such measurements. Some appropriate statistics were subsequently determined which allowed the law concerning the establishment of a circulatory index to be determined as well as its statistical distribution and pathological threshold. The results of an examination, which are presented graphically, led to the establishment of a technique (known as cartography) giving the state of the circulation in a member. The application of this technique to persons affected with arteritis allowed the validity of the law and the previously established thresholds to be verified. The apparatus was completely automated and thus gives results which are entirely objective. (author)

  18. Nuclear Parton Distribution Functions

    Energy Technology Data Exchange (ETDEWEB)

    I. Schienbein, J.Y. Yu, C. Keppel, J.G. Morfin, F. Olness, J.F. Owens

    2009-06-01

    We study nuclear effects of charged current deep inelastic neutrino-iron scattering in the framework of a {chi}{sup 2} analysis of parton distribution functions (PDFs). We extract a set of iron PDFs which are used to compute x{sub Bj}-dependent and Q{sup 2}-dependent nuclear correction factors for iron structure functions which are required in global analyses of free nucleon PDFs. We compare our results with nuclear correction factors from neutrino-nucleus scattering models and correction factors for charged-lepton--iron scattering. We find that, except for very high x{sub Bj}, our correction factors differ in both shape and magnitude from the correction factors of the models and charged-lepton scattering.

  19. Carotenoid Distribution in Nature.

    Science.gov (United States)

    Alcaíno, Jennifer; Baeza, Marcelo; Cifuentes, Víctor

    2016-01-01

    Carotenoids are naturally occurring red, orange and yellow pigments that are synthesized by plants and some microorganisms and fulfill many important physiological functions. This chapter describes the distribution of carotenoid in microorganisms, including bacteria, archaea, microalgae, filamentous fungi and yeasts. We will also focus on their functional aspects and applications, such as their nutritional value, their benefits for human and animal health and their potential protection against free radicals. The central metabolic pathway leading to the synthesis of carotenoids is described as the three following principal steps: (i) the synthesis of isopentenyl pyrophosphate and the formation of dimethylallyl pyrophosphate, (ii) the synthesis of geranylgeranyl pyrophosphate and (iii) the synthesis of carotenoids per se, highlighting the differences that have been found in several carotenogenic organisms and providing an evolutionary perspective. Finally, as an example, the synthesis of the xanthophyll astaxanthin is discussed. PMID:27485217

  20. Density Distribution Sunflower Plots

    Directory of Open Access Journals (Sweden)

    William D. Dupont

    2003-01-01

    Full Text Available Density distribution sunflower plots are used to display high-density bivariate data. They are useful for data where a conventional scatter plot is difficult to read due to overstriking of the plot symbol. The x-y plane is subdivided into a lattice of regular hexagonal bins of width w specified by the user. The user also specifies the values of l, d, and k that affect the plot as follows. Individual observations are plotted when there are less than l observations per bin as in a conventional scatter plot. Each bin with from l to d observations contains a light sunflower. Other bins contain a dark sunflower. In a light sunflower each petal represents one observation. In a dark sunflower, each petal represents k observations. (A dark sunflower with p petals represents between /2-pk k and /2+pk k observations. The user can control the sizes and colors of the sunflowers. By selecting appropriate colors and sizes for the light and dark sunflowers, plots can be obtained that give both the overall sense of the data density distribution as well as the number of data points in any given region. The use of this graphic is illustrated with data from the Framingham Heart Study. A documented Stata program, called sunflower, is available to draw these graphs. It can be downloaded from the Statistical Software Components archive at http://ideas.repec.org/c/boc/bocode/s430201.html . (Journal of Statistical Software 2003; 8 (3: 1-5. Posted at http://www.jstatsoft.org/index.php?vol=8 .

  1. CMCC Data Distribution Centre

    Science.gov (United States)

    Aloisio, Giovanni; Fiore, Sandro; Negro, A.

    2010-05-01

    The CMCC Data Distribution Centre (DDC) is the primary entry point (web gateway) to the CMCC. It is a Data Grid Portal providing a ubiquitous and pervasive way to ease data publishing, climate metadata search, datasets discovery, metadata annotation, data access, data aggregation, sub-setting, etc. The grid portal security model includes the use of HTTPS protocol for secure communication with the client (based on X509v3 certificates that must be loaded into the browser) and secure cookies to establish and maintain user sessions. The CMCC DDC is now in a pre-production phase and it is currently used only by internal users (CMCC researchers and climate scientists). The most important component already available in the CMCC DDC is the Search Engine which allows users to perform, through web interfaces, distributed search and discovery activities by introducing one or more of the following search criteria: horizontal extent (which can be specified by interacting with a geographic map), vertical extent, temporal extent, keywords, topics, creation date, etc. By means of this page the user submits the first step of the query process on the metadata DB, then, she can choose one or more datasets retrieving and displaying the complete XML metadata description (from the browser). This way, the second step of the query process is carried out by accessing to a specific XML document of the metadata DB. Finally, through the web interface, the user can access to and download (partially or totally) the data stored on the storage device accessing to OPeNDAP servers and to other available grid storage interfaces. Requests concerning datasets stored in deep storage will be served asynchronously.

  2. The Saguaro distributed operating system

    Science.gov (United States)

    Andrews, Gregory R.; Schlichting, Richard D.

    1989-05-01

    The progress achieved over the final year of the Saguaro distributed operating system project is presented. The primary achievements were in related research, including SR distributed programming language, the MLP system for constructing distributed mixed-language programs, the Psync interprocess communication mechanism, a configurable operating system kernal called the x-kernal, and the development of language mechanisms for performing failure handling in distributed programming languages.

  3. Parton distribution functions of hadrons

    International Nuclear Information System (INIS)

    The determination of the universal parton distribution functions in the QCD framework is connected to all aspects of rigorous tests of the Standard Model. Knowledge of distribution functions allows the formulation of predictions on anticipated measurements at much highr energies than are currently achievable. Topics covered in this discussion include QCD formalism for hard processes, parton distribution functions, reference processes, global analyses, and a survey of recent parton distributions. 102 refs., 5 figs

  4. Interpreting spotted dolphin age distributions

    OpenAIRE

    Barlow, Jay; Hohn, Aleta A.

    1984-01-01

    Previous work has determined the age distribution from a sample of spotted dolphins (Stenella attenuata) killed in the eastern Pacific tuna purse-seine fishery. In this paper we examine the usefulness of this age distribution for estimating natural mortality rates. The observed age distribution has a deficiency of individuals from 5-15 years and cannot represent a stable age distribution. Sampling bias and errors in age interpretation are examined as possible causes of the "dip" in the obs...

  5. Distributed Streaming with Finite Memory

    OpenAIRE

    Neven, Frank; Schweikardt, Nicole; Servais, Frédéric; Tan, Tony

    2015-01-01

    We introduce three formal models of distributed systems for query evaluation on massive databases: Distributed Streaming with Register Automata (DSAs), Distributed Streaming with Register Transducers (DSTs), and Distributed Streaming with Register Transducers and Joins (DSTJs). These models are based on the key-value paradigm where the input is transformed into a dataset of key-value pairs, and on each key a local computation is performed on the values associated with that key resulting in an...

  6. Distributed terascale volume visualization using distributed shared virtual memory

    KAUST Repository

    Beyer, Johanna

    2011-10-01

    Table 1 illustrates the impact of different distribution unit sizes, different screen resolutions, and numbers of GPU nodes. We use two and four GPUs (NVIDIA Quadro 5000 with 2.5 GB memory) and a mouse cortex EM dataset (see Figure 2) of resolution 21,494 x 25,790 x 1,850 = 955GB. The size of the virtual distribution units significantly influences the data distribution between nodes. Small distribution units result in a high depth complexity for compositing. Large distribution units lead to a low utilization of GPUs, because in the worst case only a single distribution unit will be in view, which is rendered by only a single node. The choice of an optimal distribution unit size depends on three major factors: the output screen resolution, the block cache size on each node, and the number of nodes. Currently, we are working on optimizing the compositing step and network communication between nodes. © 2011 IEEE.

  7. Universal features of multiplicity distributions

    International Nuclear Information System (INIS)

    Universal features of multiplicity distributions are studied and combinants, certain linear combinations of ratios of probabilities, are introduced. It is argued that they can be a useful tool in analyzing multiplicity distributions of hadrons emitted in high energy collisions and large scale structure of galaxy distributions

  8. Inclusões fluidas crepitadas, fluidos hipersalinos e aquo-carbônicos em quartzo associado a rochas micáceas no Granito Xinguara - Terreno Granito-Greenstone de Rio Maria, PA Decrepitated fluid inclusions, aqueous-carbonic and hypersaline fluids in quartz associated to micaceous rocks in the Xinguara Granite - Rio Maria Granite - Greenstone terrain, Pará, Brazil

    Directory of Open Access Journals (Sweden)

    Marcelo Leopoldo Weber

    2008-03-01

    Full Text Available As rochas micáceas encontradas no Granito Xinguara, terreno Granito-Greenstone de Rio Maria, Pará, são compostas por muscovita e clorita com níveis de quartzo intercalados, que formam uma xistosidade bem desenvolvida. Essa xistosidade é cortada por veios de quartzo. Ambas as gerações de quartzo apresentam os mesmos tipos de inclusões fluidas em halos ou trilhas secundárias de composições variadas entre aquosas, aquo-carbônicas e saturadas em torno de grandes inclusões primárias crepitadas ou em trilhas transgranulares secundárias. A grande variação de temperaturas de homogeneização, a alta salinidade, as evidências de estrangulamento e a existência das inclusões crepitadas permitem supor forte influência de alterações pós-formacionais e reequilíbrio relacionados à intrusão do granito. Essas rochas foliadas são, portanto, enclaves metassedimentares afetados por fluidos graníticos hipersalinos aquo-carbônicos.The micaceous rocks occurring in the Xinguara Granite, Rio Maria Granite-Greenstone terrain, Pará State, Brazil, are composed of muscovite and chlorite with quartz levels intercalated forming a well developed schistosity. This schistosity is cut by quartz veins. Both quartz generations show the same aqueous, aqueous-carbonic and halite-bearing fluid inclusions either in secondary inclusions halos and trails surrounding decrepitated primary fluid inclusions or in transgranular secondary trails. A wide variation of homogenization temperatures, high salinity, necking down and the decrepitated inclusions existence indicates strong influence of post-formational alteration and reequilibration linked to the granite intrusion. These foliated rocks are metasedimentary enclaves affected by late hypersaline aqueous-carbonic granitic fluids.

  9. The Weibull distribution a handbook

    CERN Document Server

    Rinne, Horst

    2008-01-01

    The Most Comprehensive Book on the SubjectChronicles the Development of the Weibull Distribution in Statistical Theory and Applied StatisticsExploring one of the most important distributions in statistics, The Weibull Distribution: A Handbook focuses on its origin, statistical properties, and related distributions. The book also presents various approaches to estimate the parameters of the Weibull distribution under all possible situations of sampling data as well as approaches to parameter and goodness-of-fit testing.Describes the Statistical Methods, Concepts, Theories, and Applications of T

  10. Practical quasi parton distribution functions

    CERN Document Server

    Ishikawa, Tomomi; Qiu, Jian-Wei; Yoshida, Shinsuke

    2016-01-01

    A completely new strategy to calculate parton distribution functions on the lattice has recently been proposed. In this method, lattice calculable observables, called quasi distributions, are related to normal distributions. The quasi distributions are known to contain power-law UV divergences arise from a Wilson line in the non-local operator, while the normal distributions only have logatithmic UV divergences. We propose possible method to subtract the power divegence to make the matching of the quasi with the normal distributions well-defined. We also demonstrate the matching of the quasi quark distribution between continuum and lattice implementing the power divergence subtraction. The matching calculations are carried out by one-loop perturbation.

  11. LHCb Distributed Conditions Database

    CERN Document Server

    Clemencic, Marco

    2007-01-01

    The LHCb Conditions Database project provides the necessary tools to handle non-event time-varying data. The main users of conditions are reconstruction and analysis processes, which are running on the Grid. To allow efficient access to the data, we need to use a synchronized replica of the content of the database located at the same site as the event data file, i.e. the LHCb Tier1. The replica to be accessed is selected from information stored on LFC (LCG File Catalog) and managed with the interface provided by the LCG developed library CORAL. The plan to limit the submission of jobs to those sites where the required conditions are available will also be presented. LHCb applications are using the Conditions Database framework on a production basis since March 2007. We have been able to collect statistics on the performance and effectiveness of both the LCB library COOL (the library providing conditions handling functionalities) and the distribution framework itself. Stress tests on the CNAF hosted replica o...

  12. Distributed Deliberative Recommender Systems

    Science.gov (United States)

    Recio-García, Juan A.; Díaz-Agudo, Belén; González-Sanz, Sergio; Sanchez, Lara Quijano

    Case-Based Reasoning (CBR) is one of most successful applied AI technologies of recent years. Although many CBR systems reason locally on a previous experience base to solve new problems, in this paper we focus on distributed retrieval processes working on a network of collaborating CBR systems. In such systems, each node in a network of CBR agents collaborates, arguments and counterarguments its local results with other nodes to improve the performance of the system's global response. We describe D2ISCO: a framework to design and implement deliberative and collaborative CBR systems that is integrated as a part of jcolibritwo an established framework in the CBR community. We apply D2ISCO to one particular simplified type of CBR systems: recommender systems. We perform a first case study for a collaborative music recommender system and present the results of an experiment of the accuracy of the system results using a fuzzy version of the argumentation system AMAL and a network topology based on a social network. Besides individual recommendation we also discuss how D2ISCO can be used to improve recommendations to groups and we present a second case of study based on the movie recommendation domain with heterogeneous groups according to the group personality composition and a group topology based on a social network.

  13. Distributed Project Work

    DEFF Research Database (Denmark)

    Borch, Ole; Kirkegaard, B.; Knudsen, Morten;

    1998-01-01

    Project work has been used for many years at Aalborg University to improve learning of theory and methods given in courses. In a closed environment where the students are forming a group in a single room, the interaction behaviour is more or less given from the natural life. Group work in a distr......Project work has been used for many years at Aalborg University to improve learning of theory and methods given in courses. In a closed environment where the students are forming a group in a single room, the interaction behaviour is more or less given from the natural life. Group work...... in a distributed fashion over the Internet needs more attention to the interaction protocol since the physical group room is not existing. The purpose in this paper is to develop a method for online project work by using the product: Basic Support for Cooperative Work (BSCV). An analysis of a well-proven protocol...... for information exchange in the traditional project environment is performed. A group of teachers and a student group using small project examples test the method. The first test group used a prototype for testing and found the new activity synchronization difficult to adapt, so the method was finally adjusted...

  14. Electronic procedure distribution

    International Nuclear Information System (INIS)

    Printed procedures can offer a mix of text and graphic information that improves readability and increases understanding. A typical procedure uses illustrations and graphics to clarify concepts, a variety of type styles and weights to make it easier to find different topics and sections, white space to improve readability, and familiar navigational clues such as page numbers and topic headers. Initially, electronic procedure systems had limited typeface options, often only a single typeface, with no capability for enhancing readability by varying type size bolding, italicizing, or underlining, and no ability to include graphics. Even recently, many text-only electronic procedures were originally created in a modern What-You-See-Is-What-You-Get (WYSI-WYG) document authoring system, only to be converted to pages and pages of plain type for electronic distribution. Given the choice of paper or on-line producers, most users have chosen paper for its readability. But current-generation electronic document systems that use formatted text and embedded graphics offer users vastly improved readability. Further, they are offering ever-better search tools to enable rapid location of material of interest

  15. Distributed Merge Trees

    Energy Technology Data Exchange (ETDEWEB)

    Morozov, Dmitriy; Weber, Gunther

    2013-01-08

    Improved simulations and sensors are producing datasets whose increasing complexity exhausts our ability to visualize and comprehend them directly. To cope with this problem, we can detect and extract significant features in the data and use them as the basis for subsequent analysis. Topological methods are valuable in this context because they provide robust and general feature definitions. As the growth of serial computational power has stalled, data analysis is becoming increasingly dependent on massively parallel machines. To satisfy the computational demand created by complex datasets, algorithms need to effectively utilize these computer architectures. The main strength of topological methods, their emphasis on global information, turns into an obstacle during parallelization. We present two approaches to alleviate this problem. We develop a distributed representation of the merge tree that avoids computing the global tree on a single processor and lets us parallelize subsequent queries. To account for the increasing number of cores per processor, we develop a new data structure that lets us take advantage of multiple shared-memory cores to parallelize the work on a single node. Finally, we present experiments that illustrate the strengths of our approach as well as help identify future challenges.

  16. LHCb distributed conditions database

    International Nuclear Information System (INIS)

    The LHCb Conditions Database project provides the necessary tools to handle non-event time-varying data. The main users of conditions are reconstruction and analysis processes, which are running on the Grid. To allow efficient access to the data, we need to use a synchronized replica of the content of the database located at the same site as the event data file, i.e. the LHCb Tier1. The replica to be accessed is selected from information stored on LFC (LCG File Catalog) and managed with the interface provided by the LCG developed library CORAL. The plan to limit the submission of jobs to those sites where the required conditions are available will also be presented. LHCb applications are using the Conditions Database framework on a production basis since March 2007. We have been able to collect statistics on the performance and effectiveness of both the LCG library COOL (the library providing conditions handling functionalities) and the distribution framework itself. Stress tests on the CNAF hosted replica of the Conditions Database have been performed and the results will be summarized here

  17. LHCb distributed conditions database

    Science.gov (United States)

    Clemencic, M.

    2008-07-01

    The LHCb Conditions Database project provides the necessary tools to handle non-event time-varying data. The main users of conditions are reconstruction and analysis processes, which are running on the Grid. To allow efficient access to the data, we need to use a synchronized replica of the content of the database located at the same site as the event data file, i.e. the LHCb Tier1. The replica to be accessed is selected from information stored on LFC (LCG File Catalog) and managed with the interface provided by the LCG developed library CORAL. The plan to limit the submission of jobs to those sites where the required conditions are available will also be presented. LHCb applications are using the Conditions Database framework on a production basis since March 2007. We have been able to collect statistics on the performance and effectiveness of both the LCG library COOL (the library providing conditions handling functionalities) and the distribution framework itself. Stress tests on the CNAF hosted replica of the Conditions Database have been performed and the results will be summarized here.

  18. Distribution effects of electricity tax illustrated by different distribution concepts

    International Nuclear Information System (INIS)

    This study demonstrates the significance of the choice of distribution concepts in analyses of distribution effects of electricity tax. By distribution effects are meant that life circumstances are changing. The focus is on different income concepts. Income is an important element in the life circumstances of the households. The distribution effects are studied by focusing on general income before and after tax, pension able earnings before and after tax and total consumption expenditure. The authors study how increased electricity expenses caused by a proportional increase of the electricity tax affect the households in various income groups. It is found that the burden of such an increased tax, measured by the budget part set aside for electricity, decreases with income no matter what distribution concept is used. By calculating measures of inequality for income minus electricity tax before and after the tax increase, it is found that the measures of inequality significantly depend on the choice of distribution concept

  19. Free 3-distributions: holonomy, Fefferman constructions and dual distributions

    OpenAIRE

    Armstrong, Stuart

    2007-01-01

    This paper analyses the parabolic geometries generated by a free 3-distribution in the tangent space of a manifold. It shows the existence of normal Fefferman constructions over CR and Lagrangian contact structures corresponding to holonomy reductions to SO(4,2) and SO(3,3), respectively. There is also a fascinating construction of a `dual' distribution when the holonomy reduces to $G_2'$. The paper concludes with some holonomy constructions for free $n$-distributions for $n>3$.

  20. DISTRIBUTION OF LOAD USING MOBILE AGENT IN DISTRIBUTED WEB SERVERS

    OpenAIRE

    VijayaKumar G. Dhas; V. Rhymend Uthariaraj

    2014-01-01

    The continuing growth of the World-Wide Web is placing increasing demands on popular Web servers. Many of the sites are now using distributed Web servers (i.e., groups of machines) to service the increasing number of client requests, as a single server cannot handle the workload. Incoming client requests must be distributed in some fashion among the machines in the distributed Web server to improve the performance. In the existing work, reducing the high message complexity is a challenge. Thi...