WorldWideScience

Sample records for ancestor emergence constitution

  1. Ideology, constitutional culture and institutional change: the EU constitution as reflection of Europe’s emergent postmodernism

    OpenAIRE

    Nikolay Wenzel

    2007-01-01

    Using the example of the European Constitution, this paper argues that ideology plays a much more important role in institutional change than has been indicated hitherto in the literature. Rather than being an intellectual parlor-game, Postmodernism has emerged through European high culture to find its voice in the new Constitution. Although it was rejected by a critical mass of voters, the proposed Constitution offers a telling glimpse into the European intellectual mindset – especially sinc...

  2. A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease

    DEFF Research Database (Denmark)

    Forsberg, Roald; Oleksiewicz, Martin B.; Krabbe Petersen, Anne Mette;

    2001-01-01

    The disease caused by porcine reproductive and respiratory syndrome virus (PRRSV) emerged independently and almost simultaneously in Europe (1990) and North America (1987). The original reservoir of the virus and the date it entered the pig populations is not known. In this study, we demonstrate...... an accurate molecular clock for the European PRRSV ORF 3 gene, place the root in the genealogy, estimate the rate of nucleotide substitution, and date the most recent common viral ancestor of the data set to 1979; more than 10 years before the onset of the European epidemic. Based on these findings, we...... conclude that PRRSV virus most likely entered the pig population some time before the epidemic emergence of the virus, and hence, that emergence of European-type PRRSV is not the result of a recent species transmission event. Together, our results show that ORF3 sequencing is a valuable epidemiologic tool...

  3. The galaxy ancestor problem

    CERN Document Server

    Disney, Mike

    2011-01-01

    HST finds galaxies whose Tolman dimming should exceed 10 mag. Could evolution alone explain these as our ancestor galaxies? Or could they be representatives of quite a different dynasty whose descendants are no longer prominent today? We explore this latter hypothesis and argue that Surface Brightness Selection Effects naturally bring into focus quite different dynasties from different redshifts. Thus the HST z=7 galaxies could be examples of galaxies whose descendants are both too small and too choked with dust to be recognizable in our neighborhood easily today. Conversely the ancestors of the Milky Way and its obvious neighbors will have completely sunk below the sky at z>1.2 although their diffuse light could account for the missing Reionization flux. This Succeeding Prominent Dynasties Hypothesis (SPDH) fits the existing observations both naturally and well,including the bizarre distributions of galaxy surface brightnesses found in deep fields, the angular size ~ inverse (1+z) law,'Downsizing' which turn...

  4. The galaxy ancestor problem

    Science.gov (United States)

    Disney, M. J.; Lang, R. H.

    2012-11-01

    The Hubble Space Telescope (HST) findsgalaxies whose Tolman dimming exceeds 10 mag. Could evolution alone explain these as our ancestor galaxies or could they be representatives of quite a different dynasty whose descendants are no longer prominent today? We explore the latter hypothesis and argue that surface brightness selection effects naturally bring into focus quite different dynasties from different redshifts. Thus, the HST z = 7 galaxies could be examples of galaxies whose descendants are both too small and too choked with dust to be recognizable in our neighbourhood easily today. Conversely, the ancestors of the Milky Way and its obvious neighbours would have completely sunk below the sky at z > 1.2, unless they were more luminous in the past, although their diffused light could account for the missing re-ionization flux. This Succeeding Prominent Dynasties Hypothesis (SPDH) fits the existing observations both naturally and well even without evolution, including the bizarre distributions of galaxy surface brightness found in deep fields, the angular size ˜(1 + z)-1 law, 'downsizing' which turns out to be an 'illusion' in the sense that it does not imply evolution, 'infant mortality', that is, the discrepancy between stars born and stars seen, the existence of 'red nuggets', and finally the recently discovered and unexpected excess of quasar absorption line damped Lyα systems at high redshift. If galaxies were not significantly brighter in the past and the SPDH were true, then a large proportion of galaxies could remain sunk from sight, possibly at all redshifts, and these sunken galaxies could supply the missing re-ionization flux. We show that fishing these sunken galaxies out of the sky by their optical emissions alone is practically impossible, even when they are nearby. More ingenious methods are needed to detect them. It follows that disentangling galaxy evolution through studying ever higher redshift galaxies may be a forlorn hope because one could

  5. Ancestor worship - is it Biblical?

    Directory of Open Access Journals (Sweden)

    Choon Sup Bae

    2008-01-01

    Full Text Available Ancestor worship is practiced in different forms around the world today, even in societies participating in the modern global economy. Ancestral beliefs are deeply dependent on the premise that the souls of the dead may return to the living and influence their lives; that it is possible and acceptable for the living to communicate with the dead and lastly that the living are able to exert an effect on the destiny of deceased ancestors. The following issues are most relevant to ancestor worship: 1 death and the afterlife, 2 possibility of communication between the living and the dead, and 3 the destiny of believers who die. The article looks at these issues from a Biblical perspective, offers Biblical guidelines in assessing ancestor worship and its cosmology and interprets ancestor worship theologically. The conclusion is that ancestor worship is incompatible with Christian faith.

  6. Quarantine in times of emergency: the scope of s 51(ix) of the Constitution.

    Science.gov (United States)

    Reynolds, Christopher

    2004-11-01

    This article explores the scope of s 51(ix) of the Constitution, the power of the Commonwealth to make laws with respect to "quarantine". While this power has sustained the Quarantine Act without a challenge since 1908, it may be that future national public health emergencies, such as epidemics or bioterrorism, will (as has happened in other countries) demand a level of federal preparedness that requires augmented public health powers at a national level. If so, will the scope of the quarantine power, as determined by the High Court, be wide enough allow the Commonwealth to implement these powers? While there is some advantage in a national approach, there is also some authority suggesting that the quarantine power could not extend to domestic public health controls. If there is uncertainty about the scope of the power, what are the options? Should there be another approach, with the States, Territories and the Commonwealth moving towards uniform legislation and co-operative arrangements?

  7. The emergence of alternative 3' and 5' splice site exons from constitutive exons.

    Directory of Open Access Journals (Sweden)

    Eli Koren

    2007-05-01

    Full Text Available Alternative 3' and 5' splice site (ss events constitute a significant part of all alternative splicing events. These events were also found to be related to several aberrant splicing diseases. However, only few of the characteristics that distinguish these events from alternative cassette exons are known currently. In this study, we compared the characteristics of constitutive exons, alternative cassette exons, and alternative 3'ss and 5'ss exons. The results revealed that alternative 3'ss and 5'ss exons are an intermediate state between constitutive and alternative cassette exons, where the constitutive side resembles constitutive exons, and the alternative side resembles alternative cassette exons. The results also show that alternative 3'ss and 5'ss exons exhibit low levels of symmetry (frame-preserving, similar to constitutive exons, whereas the sequence between the two alternative splice sites shows high symmetry levels, similar to alternative cassette exons. In addition, flanking intronic conservation analysis revealed that exons whose alternative splice sites are at least nine nucleotides apart show a high conservation level, indicating intronic participation in the regulation of their splicing, whereas exons whose alternative splice sites are fewer than nine nucleotides apart show a low conservation level. Further examination of these exons, spanning seven vertebrate species, suggests an evolutionary model in which the alternative state is a derivative of an ancestral constitutive exon, where a mutation inside the exon or along the flanking intron resulted in the creation of a new splice site that competes with the original one, leading to alternative splice site selection. This model was validated experimentally on four exons, showing that they indeed originated from constitutive exons that acquired a new competing splice site during evolution.

  8. Ancestors Worshipped(Jino nationality)

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    ALL Jino people will make an offering to "Api’e’e" before meals. Api’e’e is considered Jino people’s ancestor, dating back to the time when Amoyaobu created the world. At that time, human beings lived in peace and happiness and in harmony with all things on earth. Then one year the world was suddenly stricken by a flood. Crops, villages, livestock and people were drowned. Mahei and Maniu were friends living

  9. Proposed Ancestors of Phage Nucleic Acid Packaging Motors (and Cells

    Directory of Open Access Journals (Sweden)

    Philip Serwer

    2011-07-01

    Full Text Available I present a hypothesis that begins with the proposal that abiotic ancestors of phage RNA and DNA packaging systems (and cells include mobile shells with an internal, molecule-transporting cavity. The foundations of this hypothesis include the conjecture that current nucleic acid packaging systems have imprints from abiotic ancestors. The abiotic shells (1 initially imbibe and later also bind and transport organic molecules, thereby providing a means for producing molecular interactions that are links in the chain of events that produces ancestors to the first molecules that are both information carrying and enzymatically active, and (2 are subsequently scaffolds on which proteins assemble to form ancestors common to both shells of viral capsids and cell membranes. Emergence of cells occurs via aggregation and merger of shells and internal contents. The hypothesis continues by using proposed imprints of abiotic and biotic ancestors to deduce an ancestral thermal ratchet-based DNA packaging motor that subsequently evolves to integrate a DNA packaging ATPase that provides a power stroke.

  10. Viral Ancestors of Antiviral Systems

    Directory of Open Access Journals (Sweden)

    Luis P. Villarreal

    2011-10-01

    Full Text Available All life must survive their corresponding viruses. Thus antiviral systems are essential in all living organisms. Remnants of virus derived information are also found in all life forms but have historically been considered mostly as junk DNA. However, such virus derived information can strongly affect host susceptibility to viruses. In this review, I evaluate the role viruses have had in the origin and evolution of host antiviral systems. From Archaea through bacteria and from simple to complex eukaryotes I trace the viral components that became essential elements of antiviral immunity. I conclude with a reexamination of the ‘Big Bang’ theory for the emergence of the adaptive immune system in vertebrates by horizontal transfer and note how viruses could have and did provide crucial and coordinated features.

  11. Viral ancestors of antiviral systems.

    Science.gov (United States)

    Villarreal, Luis P

    2011-10-01

    All life must survive their corresponding viruses. Thus antiviral systems are essential in all living organisms. Remnants of virus derived information are also found in all life forms but have historically been considered mostly as junk DNA. However, such virus derived information can strongly affect host susceptibility to viruses. In this review, I evaluate the role viruses have had in the origin and evolution of host antiviral systems. From Archaea through bacteria and from simple to complex eukaryotes I trace the viral components that became essential elements of antiviral immunity. I conclude with a reexamination of the 'Big Bang' theory for the emergence of the adaptive immune system in vertebrates by horizontal transfer and note how viruses could have and did provide crucial and coordinated features.

  12. The emerging international constitutional order: the implications of hierarchy in international law for the coherence and legitimacy of international decision-making

    Directory of Open Access Journals (Sweden)

    E de Wet

    2007-11-01

    Full Text Available The article examines the contours and implications of the emerging international constitutional order. The "constitutional" nature of this order relates to the fact that it contains certain fundamental substantive and structural norms that form a supreme legal framework for the exercise of public power. The substantive elements primarily include the value system of the international legal order, meaning norms of positive law with a strong ethical underpinning (notably human rights norms that have acquired a special hierarchical standing vis-à-vis other international norms through state practice. The structural elements refer to the subjects of the international legal order that collectively constitute the international community (polity, as well as the mechanisms for enforcement of the international value system. This vision of an international constitutional model is inspired by the intensification in the shift of public decision-making away from the nation state towards international actors of a regional (for example EU or functional (for example WTO, UN nature, and its eroding impact on the notion of a “total” constitutional order, where the fundamental substantive and structural norms that form the supreme legal framework for the exercise of public power are concentrated in the nation state. It is also inspired by the belief that such a supreme legal framework is only possible in a system where different national, regional and functional legal orders complement each other in order to form an international constitutional order.

  13. Apparatus Named after Our Academic Ancestors, III

    Science.gov (United States)

    Greenslade, Thomas B., Jr.

    2014-01-01

    My academic ancestors in physics have called on me once more to tell you about the apparatus that they devised, and that many of you have used in your demonstrations and labs. This article is about apparatus named after François Arago, Heinrich Helmholtz, Leon Foucault, and James Watt.

  14. Apparatus Named After Our Academic Ancestors, III

    Science.gov (United States)

    Greenslade, Thomas B.

    2014-09-01

    My academic ancestors in physics have called on me once more to tell you about the apparatus that they devised, and that many of you have used in your demonstrations and labs. This article is about apparatus named after François Arago, Heinrich Helmholtz, Leon Foucault, and James Watt.

  15. Windmills: Ancestors of the wind power generation

    Science.gov (United States)

    Rossi, Cesare; Russo, Flavio; Savino, Sergio

    2016-12-01

    A brief description of the windmills from the second millennium BC to the Renaissance is presented. This survey is a part of several studies conducted by the authors on technology in the ancient world. The windmills are the first motor, other than human muscles, and are the ancestors of the modern wind turbines. Some authors' virtual reconstructions of old windmills are also presented. The paper shows that the operating principle of many modern machines had already been conceived in the ancient times by using a technology that was more advanced than expected, but with two main differences, as follows: Similar tasks were accomplished by using much less energy; and the environmental impact was nil or very low. Modern designers should sometimes consider simplicity rather than the use of a large amount of energy.

  16. Constitutive Models

    DEFF Research Database (Denmark)

    2011-01-01

    This chapter presents various types of constitutive models and their applications. There are 3 aspects dealt with in this chapter, namely: creation and solution of property models, the application of parameter estimation and finally application examples of constitutive models. A systematic...

  17. Dating the cyanobacterial ancestor of the chloroplast.

    Science.gov (United States)

    Falcón, Luisa I; Magallón, Susana; Castillo, Amanda

    2010-06-01

    Cyanobacteria have had a pivotal role in the history of life on Earth being the first organisms to perform oxygenic photosynthesis, which changed the atmospheric chemistry and allowed the evolution of aerobic Eukarya. Chloroplasts are the cellular organelles of photoautotrophic eukaryotes in which most portions of photosynthesis occur. Although the initial suggestion that cyanobacteria are the ancestors of chloroplasts was greeted with skepticism, the idea is now widely accepted. Here we attempt to resolve and date the cyanobacterial ancestry of the chloroplast using phylogenetic analysis and molecular clocks. We found that chloroplasts form a monophyletic lineage, are most closely related to subsection-I, N(2)-fixing unicellular cyanobacteria (Order Chroococcales), and heterocyst-forming Order Nostocales cyanobacteria are their sister group. Nostocales and Chroococcales appeared during the Paleoproterozoic and chloroplasts appeared in the mid-Proterozoic. The capability of N(2) fixation in cyanobacteria may have appeared only once during the late Archaean and early Proterozoic eons. Furthermore, we found that oxygen-evolving cyanobacteria could have appeared in the Archaean. Our results suggest that a free-living cyanobacterium with the capacity to store starch through oxygenic CO(2) fixation, and to fix atmospheric N(2), would be a very important intracellular acquisition, which, as can be recounted today from several lines of evidence, would have become the chloroplast by endosymbiosis.

  18. Extensive intron gain in the ancestor of placental mammals

    Directory of Open Access Journals (Sweden)

    Kordiš Dušan

    2011-11-01

    Full Text Available Abstract Background Genome-wide studies of intron dynamics in mammalian orthologous genes have found convincing evidence for loss of introns but very little for intron turnover. Similarly, large-scale analysis of intron dynamics in a few vertebrate genomes has identified only intron losses and no gains, indicating that intron gain is an extremely rare event in vertebrate evolution. These studies suggest that the intron-rich genomes of vertebrates do not allow intron gain. The aim of this study was to search for evidence of de novo intron gain in domesticated genes from an analysis of their exon/intron structures. Results A phylogenomic approach has been used to analyse all domesticated genes in mammals and chordates that originated from the coding parts of transposable elements. Gain of introns in domesticated genes has been reconstructed on well established mammalian, vertebrate and chordate phylogenies, and examined as to where and when the gain events occurred. The locations, sizes and amounts of de novo introns gained in the domesticated genes during the evolution of mammals and chordates has been analyzed. A significant amount of intron gain was found only in domesticated genes of placental mammals, where more than 70 cases were identified. De novo gained introns show clear positional bias, since they are distributed mainly in 5' UTR and coding regions, while 3' UTR introns are very rare. In the coding regions of some domesticated genes up to 8 de novo gained introns have been found. Intron densities in Eutheria-specific domesticated genes and in older domesticated genes that originated early in vertebrates are lower than those for normal mammalian and vertebrate genes. Surprisingly, the majority of intron gains have occurred in the ancestor of placentals. Conclusions This study provides the first evidence for numerous intron gains in the ancestor of placental mammals and demonstrates that adequate taxon sampling is crucial for

  19. Near-optimal labeling schemes for nearest common ancestors

    DEFF Research Database (Denmark)

    Alstrup, Stephen; Bistrup Halvorsen, Esben; Larsen, Kasper Green

    2014-01-01

    and Korman (STOC'10) established that labels in ancestor labeling schemes have size log n + Θ(log log n), our new lower bound separates ancestor and NCA labeling schemes. Our upper bound improves the 10 log n upper bound by Alstrup, Gavoille, Kaplan and Rauhe (TOCS'04), and our theoretical result even...

  20. Developmental Constitutionalism

    OpenAIRE

    Skupien, Stefan

    2015-01-01

    The search for adequate political and socio-economic models continues within recent constitutional reforms in Sub-Saharan post-colonial societies since 2005. This discourse goes back to the period of decolonisation but also to the transitions after 1989. Within this study, I assess the problem of representational crisis that come hand in hand with constitution making processes. Especially, I focus on the representation of different groups within the state, the safeguarding and extent of basic...

  1. Constitutional Conservatism

    Science.gov (United States)

    Berkowitz, Peter

    2009-01-01

    After their dismal performance in election 2008, conservatives are taking stock. As they examine the causes that have driven them into the political wilderness and as they explore paths out, they should also take heart. After all, election 2008 shows that America's constitutional order is working as designed. Indeed, while sorting out their errors…

  2. The origin of life and the last universal common ancestor: do we need a change of perspective?

    Science.gov (United States)

    Glansdorff, Nicolas; Xu, Ying; Labedan, Bernard

    2009-09-01

    A complete tree with roots, trunk and crown remains an appropriate model to represent all steps of life's development, from the emergence of a unique genetic code up to the last universal common ancestor and its further radiation. Catalytic closure of a mixture of prebiotic polymers is a heuristic alternative to the RNA world. Conjectures about emergence of life in an infinite multiverse should not confuse probability with possibility.

  3. Did the last common ancestor have a biological membrane?

    Directory of Open Access Journals (Sweden)

    Jékely Gáspár

    2006-11-01

    Full Text Available Abstract All theories about the origin and evolution of membrane bound cells necessarily have to cope with the nature of the last common ancestor of cellular life. One of the most important aspect of this ancestor, whether it had a closed biological membrane or not, has recently been intensely debated. Having a consensus about it would be an important step towards an eventual (though probably still remote synthesis of the best elements of the current multitude of cell evolution models. Here I analyse the structural and functional conservation of the few universally distributed proteins that were undoubtedly present in the last common ancestor and that carry out membrane-associated functions. These include the SecY subunit of the protein-conducting channel, the signal recognition particle, the signal recognition particle receptor, the signal peptidase, and the proton ATPase. The conserved structural and functional aspects of these proteins indicate that the last common ancestor was associated with a hydrophobic layer with two hydrophilic sides (an inside and an outside that had a full-fledged and asymmetric protein insertion and translocation machinery and served as a permeability barrier for protons and other small molecules. It is difficult to escape the conclusion that the last common ancestor had a closed biological membrane from which all cellular membranes evolved.

  4. Photographs of the 369th Infantry and African Americans during World War I. The Constitution Community: The Emergence of Modern America (1890-1930).

    Science.gov (United States)

    Schur, Joan Brodsky

    In April 1917, President Woodrow Wilson asked Congress to declare war on Germany. Under the powers granted to it by the U.S. Constitution, Congress passed the Selective Service Act of 1917. Among the first regiments to arrive in France, and among the most highly decorated when it returned, was the 369th Infantry, more gallantly known as the…

  5. THE CELULAR JUNCTIONS AND THE EMERGENCE OF ANIMALS

    Directory of Open Access Journals (Sweden)

    Urquiza-Bardone, Sergio

    2013-07-01

    Full Text Available The emergence of multicellularity and epithelia in relation to the appearance of cellular junctions, in order to illustrate the first steps of animal evolution, is discussed. We analyzed the structure and roles of adherens and occludins, considered to be the oldest. Also treated are some aspects of the main proteins that constitute them, the cadherins and claudins, as well as the related structures observed in sponges and choanoflagellates, the most ancient animals and the ancestors of these, respectively. It was concluded that the animal ancestor probably possessed some kind of adherens and possibly occludins, appearing as the first of major importance. These junctions increased in complexity through until the complexity observed in modern times.

  6. Emperors and Ancestors. Roman Rulers and the Constraints of Tradition

    NARCIS (Netherlands)

    Hekster, O.J.

    2015-01-01

    Ancestry played a continuous role in the construction and portrayal of Roman emperorship in the first three centuries AD. Emperors and Ancestors is the first systematic analysis of the different ways in which imperial lineage was represented in the various 'media' through which images of emperors co

  7. Phylogenomic reconstruction indicates mitochondrial ancestor was an energy parasite.

    Science.gov (United States)

    Wang, Zhang; Wu, Martin

    2014-01-01

    Reconstruction of mitochondrial ancestor has great impact on our understanding of the origin of mitochondria. Previous studies have largely focused on reconstructing the last common ancestor of all contemporary mitochondria (proto-mitochondria), but not on the more informative pre-mitochondria (the last common ancestor of mitochondria and their alphaproteobacterial sister clade). Using a phylogenomic approach and leveraging on the increased taxonomic sampling of alphaproteobacterial and eukaryotic genomes, we reconstructed the metabolisms of both proto-mitochondria and pre-mitochondria. Our reconstruction depicts a more streamlined proto-mitochondrion than these predicted by previous studies, and revealed several novel insights into the mitochondria-derived eukaryotic metabolisms including the lipid metabolism. Most strikingly, pre-mitochondrion was predicted to possess a plastid/parasite type of ATP/ADP translocase that imports ATP from the host, which posits pre-mitochondrion as an energy parasite that directly contrasts with the current role of mitochondria as the cell's energy producer. In addition, pre-mitochondrion was predicted to encode a large number of flagellar genes and several cytochrome oxidases functioning under low oxygen level, strongly supporting the previous finding that the mitochondrial ancestor was likely motile and capable of oxidative phosphorylation under microoxic condition.

  8. The Waikato river: Changing properties of a living Maori ancestor

    NARCIS (Netherlands)

    Meijl, A.H.M. van

    2015-01-01

    In Maori cosmology, rivers and other waterways are conceptualised as living ancestors, who have their own life force and spiritual strength. The special status of rivers in Maori society also explains why they are sometimes separated from other Maori claims to natural resources of which they were di

  9. In Search of the Ancestors of Chinese People

    Institute of Scientific and Technical Information of China (English)

    GAO Xing; WANG Chunxue

    2010-01-01

    @@ Presently,the research on the origin of Chinese ancestors focuses on two issues,namely the origin of the first human populations in Asia and the origin of modern Chinese people.Up till now,all the fossils of Australopithecus and Homo habilis,the earliest two stages of human evolution,are from Africa,and no human fossil earlier than2.0 million years ago is available outside of this continent.

  10. Diet and the evolution of the earliest human ancestors

    OpenAIRE

    Mark F. Teaford; Peter S Ungar

    2000-01-01

    Over the past decade, discussions of the evolution of the earliest human ancestors have focused on the locomotion of the australopithecines. Recent discoveries in a broad range of disciplines have raised important questions about the influence of ecological factors in early human evolution. Here we trace the cranial and dental traits of the early australopithecines through time, to show that between 4.4 million and 2.3 million years ago, the dietary capabilities of...

  11. State Constitutional Law: Teaching and Scholarship.

    Science.gov (United States)

    Williams, Robert F.

    1991-01-01

    State constitutional law is an emerging area for legal education, partly because of state supreme court decisions relying on state rather than federal constitutional law. Studying state constitutional law highlights similarities and diversity of legal and governmental systems. Interest in establishment of curricula and materials in state law is…

  12. Ancestor reverence and mental health in South Africa.

    Science.gov (United States)

    Berg, Astrid

    2003-06-01

    The great majority of South Africa's people consult traditional healers. The deeper meaning of much traditional healing centres on ancestor reverence. This belief system and its accompanying rituals may positively influence the mental health of the individual and the community. Among traditional Xhosa-speaking peoples, the relationship with the ancestors is given expression in life cycle rituals that have much in common with Western psychotherapeutic principles and practices. The common thread that underpins many rituals is that of making links via concrete, literal means. Examples include the participation of the community in the healing of the individual; the linking of body and mind through dancing and drumming. Dreams form an essential connection between conscious life and the unconscious. Understanding the psychological depth of these practices is important so that a respectful relationship between Western-trained professionals and traditional healers can develop. Analytical psychology, with its notion of the collective unconscious has a particular contribution to make to cross-cultural understanding. The ancestors may be understood as archetypal representations of the collective unconscious.

  13. Diet and the evolution of the earliest human ancestors.

    Science.gov (United States)

    Teaford, M F; Ungar, P S

    2000-12-05

    Over the past decade, discussions of the evolution of the earliest human ancestors have focused on the locomotion of the australopithecines. Recent discoveries in a broad range of disciplines have raised important questions about the influence of ecological factors in early human evolution. Here we trace the cranial and dental traits of the early australopithecines through time, to show that between 4.4 million and 2.3 million years ago, the dietary capabilities of the earliest hominids changed dramatically, leaving them well suited for life in a variety of habitats and able to cope with significant changes in resource availability associated with long-term and short-term climatic fluctuations.

  14. Hybrid origin of the Pliocene ancestor of wild goats.

    Science.gov (United States)

    Ropiquet, Anne; Hassanin, Alexandre

    2006-11-01

    Recent theories on speciation suggest that interspecific hybridization is an important mechanism for explaining adaptive radiation. According to this view, hybridization can promote the rapid transfer of adaptations between different species; the hybrid population thus invades new habitats and diversifies into a variety of new species. Although hybridization is well accepted as a fairly common mechanism for diversification in plants, its role in the evolution of animals is more controversial, because reduced fitness would typically condemn animal hybrids to an evolutionary dead-end. Here, we examine DNA sequences of four mitochondrial and four nuclear genes selected for resolving phylogenetic relationships between goats, sheep, and their allies. Our analyses provide evidence of strong discordance for the position of Capra between mitochondrial and nuclear phylogenies. We suggest that the common ancestor of wild goats arose from interspecific hybridization, and that the mitochondrial genome of a species better adapted to life at high altitudes was transferred via this route into the common ancestor of Capra. We propose that the acquisition of more efficient mitochondria has conferred a selective advantage on goats, allowing their rapid adaptive radiation during the Plio-Pleistocene epoch. Our study therefore agrees with theories that predict an important role for interspecific hybridization in the evolution and diversification of animal species.

  15. Ontogeny of the maxilla in Neanderthals and their ancestors.

    Science.gov (United States)

    Lacruz, Rodrigo S; Bromage, Timothy G; O'Higgins, Paul; Arsuaga, Juan-Luis; Stringer, Chris; Godinho, Ricardo Miguel; Warshaw, Johanna; Martínez, Ignacio; Gracia-Tellez, Ana; de Castro, José María Bermúdez; Carbonell, Eudald

    2015-12-07

    Neanderthals had large and projecting (prognathic) faces similar to those of their putative ancestors from Sima de los Huesos (SH) and different from the retracted modern human face. When such differences arose during development and the morphogenetic modifications involved are unknown. We show that maxillary growth remodelling (bone formation and resorption) of the Devil's Tower (Gibraltar 2) and La Quina 18 Neanderthals and four SH hominins, all sub-adults, show extensive bone deposition, whereas in modern humans extensive osteoclastic bone resorption is found in the same regions. This morphogenetic difference is evident by ∼5 years of age. Modern human faces are distinct from those of the Neanderthal and SH fossils in part because their postnatal growth processes differ markedly. The growth remodelling identified in these fossil hominins is shared with Australopithecus and early Homo but not with modern humans suggesting that the modern human face is developmentally derived.

  16. Before the dawn recovering the lost history of our ancestors

    CERN Document Server

    Wade, Nicholas

    2007-01-01

    Nicholas Wade’s articles are a major reason why the science section has become the most popular, nationwide, in the New York Times. In his groundbreaking Before the Dawn, Wade reveals humanity’s origins as never before—a journey made possible only recently by genetic science, whose incredible findings have answered such questions as: What was the first human language like? How large were the first societies, and how warlike were they? When did our ancestors first leave Africa, and by what route did they leave? By eloquently solving these and numerous other mysteries, Wade offers nothing less than a uniquely complete retelling of a story that began 500 centuries ago.

  17. Cassava genome from a wild ancestor to cultivated varieties.

    Science.gov (United States)

    Wang, Wenquan; Feng, Binxiao; Xiao, Jingfa; Xia, Zhiqiang; Zhou, Xincheng; Li, Pinghua; Zhang, Weixiong; Wang, Ying; Møller, Birger Lindberg; Zhang, Peng; Luo, Ming-Cheng; Xiao, Gong; Liu, Jingxing; Yang, Jun; Chen, Songbi; Rabinowicz, Pablo D; Chen, Xin; Zhang, Hong-Bin; Ceballos, Henan; Lou, Qunfeng; Zou, Meiling; Carvalho, Luiz J C B; Zeng, Changying; Xia, Jing; Sun, Shixiang; Fu, Yuhua; Wang, Haiyan; Lu, Cheng; Ruan, Mengbin; Zhou, Shuigeng; Wu, Zhicheng; Liu, Hui; Kannangara, Rubini Maya; Jørgensen, Kirsten; Neale, Rebecca Louise; Bonde, Maya; Heinz, Nanna; Zhu, Wenli; Wang, Shujuan; Zhang, Yang; Pan, Kun; Wen, Mingfu; Ma, Ping-An; Li, Zhengxu; Hu, Meizhen; Liao, Wenbin; Hu, Wenbin; Zhang, Shengkui; Pei, Jinli; Guo, Anping; Guo, Jianchun; Zhang, Jiaming; Zhang, Zhengwen; Ye, Jianqiu; Ou, Wenjun; Ma, Yaqin; Liu, Xinyue; Tallon, Luke J; Galens, Kevin; Ott, Sandra; Huang, Jie; Xue, Jingjing; An, Feifei; Yao, Qingqun; Lu, Xiaojing; Fregene, Martin; López-Lavalle, L Augusto Becerra; Wu, Jiajie; You, Frank M; Chen, Meili; Hu, Songnian; Wu, Guojiang; Zhong, Silin; Ling, Peng; Chen, Yeyuan; Wang, Qinghuang; Liu, Guodao; Liu, Bin; Li, Kaimian; Peng, Ming

    2014-10-10

    Cassava is a major tropical food crop in the Euphorbiaceae family that has high carbohydrate production potential and adaptability to diverse environments. Here we present the draft genome sequences of a wild ancestor and a domesticated variety of cassava and comparative analyses with a partial inbred line. We identify 1,584 and 1,678 gene models specific to the wild and domesticated varieties, respectively, and discover high heterozygosity and millions of single-nucleotide variations. Our analyses reveal that genes involved in photosynthesis, starch accumulation and abiotic stresses have been positively selected, whereas those involved in cell wall biosynthesis and secondary metabolism, including cyanogenic glucoside formation, have been negatively selected in the cultivated varieties, reflecting the result of natural selection and domestication. Differences in microRNA genes and retrotransposon regulation could partly explain an increased carbon flux towards starch accumulation and reduced cyanogenic glucoside accumulation in domesticated cassava. These results may contribute to genetic improvement of cassava through better understanding of its biology.

  18. Right Product, Wrong Packaging: Not 'Constitution', but 'Constitutional Charter'

    Directory of Open Access Journals (Sweden)

    John Law

    2007-05-01

    Full Text Available The article seeks to locate the principal cause of Europe’s prevailing ratification crisis in the inappropriate title arrived at in the European Convention, Treaty Establishing a Constitution for Europe. This over-ambitious styling led the media to characterise the text as simply an ‘EU Constitution’. Yet, the text was not a Constitution as we traditionally understand the term, i.e. the founding document of a State: scholars are agreed that the EU is not, and will not become upon ratification, a State.In terms of substance, whilst the text certainly strengthened some emerging constitutional aspects, it was not a major departure from the status quo like the Single European Act and Treaty on European Union had been; and it remained technically a treaty like all its predecessors. Arguably, therefore, it did not require referenda to ratify. However, confusion over the scale and importance of what was proposed, stemming from ambiguity in the title, pushed politicians down this unfortunate path.The article identifies a high level of consensus among commentators as to the true nature of the text: most are happy designating it a treaty (noun with constitutional (adjective aspects. The early proposed title Constitutional Treaty for Europe was arguably, therefore, the correct one; but it is now too late to choose this option, as the terms Constitution and Constitutional Treaty have already been muddled in debate. A more distinctive change is required. One idea could be to follow the principle employed elsewhere in the text of codifying the generally accepted but presently unwritten legal concepts of the European Court of Justice, as was done for example for ‘primacy’ and ‘direct effect’. The Court has characterised the EU treaties as a ‘constitutional charter’ for over twenty years now, and on this basis a modified title could read Treaty Establishing a Constitutional Charter for Europe. Importantly, the term ‘charter’ is recognised

  19. Population genetics of foxtail millet and its wild ancestor

    Directory of Open Access Journals (Sweden)

    Wang Yongfang

    2010-10-01

    Full Text Available Abstract Background Foxtail millet (Setaria italica (L. P. Beauv., one of the most ancient domesticated crops, is becoming a model system for studying biofuel crops and comparative genomics in the grasses. However, knowledge on the level of genetic diversity and linkage disequilibrium (LD is very limited in this crop and its wild ancestor, green foxtail (Setaria viridis (L. P. Beauv.. Such information would help us to understand the domestication process of cultivated species and will allow further research in these species, including association mapping and identification of agricultural significant genes involved in domestication. Results In this study, we surveyed DNA sequence for nine loci across 50 accessions of cultivated foxtail millet and 34 of its wild progenitor. We found a low level of genetic diversity in wild green foxtail (θ = 0.0059, θ means Watterson's estimator of θ. Despite of a 55% loss of its wild diversity, foxtail millet still harbored a considerable level of diversity (θ = 0.0027 when compared to rice and sorghum (θ = 0.0024 and 0.0034, respectively. The level of LD in the domesticated foxtail millet extends to 1 kb, while it decayed rapidly to a negligible level within 150 bp in wild green foxtail. Using coalescent simulation, we estimated the bottleneck severity at k = 0.6095 when ρ/θ = 1. These results indicated that the domestication bottleneck of foxtail millet was more severe than that of maize but slightly less pronounced than that of rice. Conclusions The results in this study establish a general framework for the domestication history of foxtail millet. The low level of genetic diversity and the increased level of LD in foxtail millet are mainly caused by a population bottleneck, although gene flow from foxtail millet to green foxtail is another factor that may have shaped the pattern of genetic diversity of these two related gene pools. The knowledge provided in this study will benefit future population

  20. Some Problems in Proving the Existence of the Universal Common Ancestor of Life on Earth

    Directory of Open Access Journals (Sweden)

    Takahiro Yonezawa

    2012-01-01

    Full Text Available Although overwhelming circumstantial evidence supports the existence of the universal common ancestor of all extant life on Earth, it is still an open question whether the universal common ancestor existed or not. Theobald (Nature 465, 219–222 (2010 recently challenged this problem with a formal statistical test applied to aligned sequences of conservative proteins sampled from all domains of life and concluded that the universal common ancestor hypothesis holds. However, we point out that there is a fundamental flaw in Theobald's method which used aligned sequences. We show that the alignment gives a strong bias for the common ancestor hypothesis, and we provide an example that Theobald's method supports a common ancestor hypothesis for two apparently unrelated families of protein-encoding sequences (cytb and nd2 of mitochondria. This arouses suspicion about the effectiveness of the “formal” test.

  1. A Global Labour Constitution?

    OpenAIRE

    Dukes, R.

    2014-01-01

    This article explores the argument that the idea of the labour constitution, as developed by Hugo Sinzheimer, offers a useful perspective for thinking about labour law today. With reference to the work of Wolfgang Streeck and Karl Polanyi, it highlights the potential benefits of the labour constitution as a framework for analysis. With a view to developing and updating Sinzheimer’s blueprint for a – national – labour constitution, it then engages with two lines of theoretical enquiry into the...

  2. Tracing ancestor rice of Suriname Maroons back to its African origin.

    Science.gov (United States)

    van Andel, Tinde R; Meyer, Rachel S; Aflitos, Saulo A; Carney, Judith A; Veltman, Margaretha A; Copetti, Dario; Flowers, Jonathan M; Havinga, Reinout M; Maat, Harro; Purugganan, Michael D; Wing, Rod A; Schranz, M Eric

    2016-10-03

    African rice (Oryza glaberrima) and African cultivation practices are said to have influenced emerging colonial plantation economies in the Americas(1,2). However, the level of impact of African rice practices is difficult to establish because of limited written or botanical records(2,3). Recent findings of O. glaberrima in rice fields of Suriname Maroons bear evidence of the high level of knowledge about rice among African slaves and their descendants, who consecrate it in ancestor rituals(4,5). Here we establish the strong similarity, and hence likely origin, of the first extant New World landrace of O. glaberrima to landraces from the Upper Guinean forests in West Africa. We collected African rice from a Maroon market in Paramaribo, Suriname, propagated it, sequenced its genome(6) and compared it with genomes of 109 accessions representing O. glaberrima diversity across West Africa. By analysing 1,649,769 single nucleotide polymorphisms (SNPs) in clustering analyses, the Suriname sample appears sister to an Ivory Coast landrace, and shows no evidence of introgression from Asian rice. Whereas the Dutch took most slaves from Ghana, Benin and Central Africa(7), the diaries of slave ship captains record the purchase of food for provisions when sailing along the West African Coast(8), offering one possible explanation for the patterns of genetic similarity. This study demonstrates the utility of genomics in understanding the largely unwritten histories of crop cultures of diaspora communities.

  3. Interpreting the Constitution.

    Science.gov (United States)

    Brennan, William J., Jr.

    1987-01-01

    Discusses constitutional interpretations relating to capital punishment and protection of human dignity. Points out the document's effectiveness in creating a new society by adapting its principles to current problems and needs. Considers two views of the Constitution that lead to controversy over the legitimacy of judicial decisions. (PS)

  4. The Constitution by Cell

    Science.gov (United States)

    Greenhut, Stephanie; Jones, Megan

    2010-01-01

    On their visit to the National Archives Experience in Washington, D.C., students in Jenni Ashley and Gay Brock's U.S. history classes at the Potomac School in McLean, Virginia, participated in a pilot program called "The Constitution by Cell." Armed with their cell phones, a basic understanding of the Constitution, and a willingness to participate…

  5. The Constitution by Cell

    Science.gov (United States)

    Greenhut, Stephanie; Jones, Megan

    2010-01-01

    On their visit to the National Archives Experience in Washington, D.C., students in Jenni Ashley and Gay Brock's U.S. history classes at the Potomac School in McLean, Virginia, participated in a pilot program called "The Constitution by Cell." Armed with their cell phones, a basic understanding of the Constitution, and a willingness to…

  6. A new theory for the distribution of ancestors in biparental reproduction species

    CERN Document Server

    Caruso, M

    2011-01-01

    To calculate the number of ancestor of one individual from any biparental reproduction specie is necessary to use an statistical approach. It's not possible to build the progenitor's tree only assuming that the spice has a sexual biparental reproduction. In particular it not true that the simple progression of $2^{t+1}$ describes in a realistic way the number of ancestors after a few generations. The reason is that when we go back in generations the probability of some ancestors been relatives has an increase. This implies a restriction in the ancestor's mean number respect of $2^{t+1}$. Although this number correspond to the maximum ancestor's number in the $t$-generation. Considering the possibility of blood relationship between the ancestors, we show how to re-build the progenitor's tree by modeling our problem with a Markov's Chain. First we work in a continuous time variable and then by doing a discretization process we obteined the ancestor's distribution. Using covariant derivative in a proper way we n...

  7. Buds of the tree: the highway to the last universal common ancestor

    Science.gov (United States)

    de Farias, Savio Torres; Prosdocimi, Francisco

    2017-04-01

    The last universal common ancestor (LUCA) has been considered as the branching point on which Bacteria, Archaea and Eukaryotes have diverged. However, the increased information relating to viruses' genomes and the perception that many virus genes do not have homologs in other organisms opened a new discussion. Based on these facts, there has emerged the idea of an early LUCA that should be moved further into the past to include viruses, implicating that life should have originated before the appearance of cellular life forms. Another point of view from advocates of the RNA-world suggests that the origin of life happened a long time before organisms were capable of organizing themselves into cellular entities. Relevant data about the origin of ribosomes indicate that the catalytic unit of the large ribosomal subunit is what should actually be considered as the turning point that separated chemistry from biology. Other researchers seem to think that a tRNA was probably some sort of a strange attractor on which life has originated. Here we propose a theoretical synthesis that tries to provide a crosstalk among the theories and define important points on which the origin of life could have been originated and made more complex, taking into account gradualist assumptions. Thus, discussions involving the origin of biological activities in the RNA-world might lead into a world of progenotes on which viruses have been taken part until the appearance of the very first cells. Along this route of complexification, we identified some key points on which researchers may consider life as an emerging principle.

  8. Molecular paleontology and complexity in the last eukaryotic common ancestor.

    Science.gov (United States)

    Koumandou, V Lila; Wickstead, Bill; Ginger, Michael L; van der Giezen, Mark; Dacks, Joel B; Field, Mark C

    2013-01-01

    Eukaryogenesis, the origin of the eukaryotic cell, represents one of the fundamental evolutionary transitions in the history of life on earth. This event, which is estimated to have occurred over one billion years ago, remains rather poorly understood. While some well-validated examples of fossil microbial eukaryotes for this time frame have been described, these can provide only basic morphology and the molecular machinery present in these organisms has remained unknown. Complete and partial genomic information has begun to fill this gap, and is being used to trace proteins and cellular traits to their roots and to provide unprecedented levels of resolution of structures, metabolic pathways and capabilities of organisms at these earliest points within the eukaryotic lineage. This is essentially allowing a molecular paleontology. What has emerged from these studies is spectacular cellular complexity prior to expansion of the eukaryotic lineages. Multiple reconstructed cellular systems indicate a very sophisticated biology, which by implication arose following the initial eukaryogenesis event but prior to eukaryotic radiation and provides a challenge in terms of explaining how these early eukaryotes arose and in understanding how they lived. Here, we provide brief overviews of several cellular systems and the major emerging conclusions, together with predictions for subsequent directions in evolution leading to extant taxa. We also consider what these reconstructions suggest about the life styles and capabilities of these earliest eukaryotes and the period of evolution between the radiation of eukaryotes and the eukaryogenesis event itself.

  9. Beyond the Economic Constitution

    DEFF Research Database (Denmark)

    Kjær, Poul F.

    -twentieth century. In particular, the “turn to corporatism” in the interwar period implied an erosion of the fragile institutionalisation of legally-constituted public power due to its suspension of the legal infrastructure of society and the concomitant breakdown of the distinction between the public and private...... realms of society. The (trans-) national re-constitution of Western Europe in the years immediately after WWII, which the European integration process was an integrated part of, successfully remedied this development. However, over the last decades, Europe, together with the rest of the world, has...

  10. Constitutional Law--Elective.

    Science.gov (United States)

    Gallagher, Joan; Wood, Robert J.

    The elective unit on Constitutional Law is intended for 11th and 12th grade students. The unit is designed around major course goals which are to develop those concepts whereby students recognize and understand the following three topic areas: 1) Role of the Federal Judicial Branch of Government, 2) Supreme Court Cases Involving the Three Branches…

  11. Crushed Salt Constitutive Model

    Energy Technology Data Exchange (ETDEWEB)

    Callahan, G.D.

    1999-02-01

    The constitutive model used to describe the deformation of crushed salt is presented in this report. Two mechanisms -- dislocation creep and grain boundary diffusional pressure solution -- are combined to form the basis for the constitutive model governing the deformation of crushed salt. The constitutive model is generalized to represent three-dimensional states of stress. Upon complete consolidation, the crushed-salt model reproduces the Multimechanism Deformation (M-D) model typically used for the Waste Isolation Pilot Plant (WIPP) host geological formation salt. New shear consolidation tests are combined with an existing database that includes hydrostatic consolidation and shear consolidation tests conducted on WIPP and southeastern New Mexico salt. Nonlinear least-squares model fitting to the database produced two sets of material parameter values for the model -- one for the shear consolidation tests and one for a combination of the shear and hydrostatic consolidation tests. Using the parameter values determined from the fitted database, the constitutive model is validated against constant strain-rate tests. Shaft seal problems are analyzed to demonstrate model-predicted consolidation of the shaft seal crushed-salt component. Based on the fitting statistics, the ability of the model to predict the test data, and the ability of the model to predict load paths and test data outside of the fitted database, the model appears to capture the creep consolidation behavior of crushed salt reasonably well.

  12. The Constitution in Action

    Science.gov (United States)

    Potter, Lee Ann

    2007-01-01

    In this article, the author describes the experiences middle school students on a field trip to the new Constitution in Action Learning Lab in the Boeing Learning Center at the National Archives can expect. There, middle school students take on the roles of archivists and researchers collecting and analyzing primary sources from the holdings of…

  13. The Constitution of Partnering

    DEFF Research Database (Denmark)

    Gottlieb, Stefan Christoffer

    The constitution of partnering. Afhandlingen behandler konstitueringen af ledelseskonceptet partnering og dets anvendelse i dansk byggeri. Partnering er et udbredt koncept i byggeriet som betoner samarbejde, tillid og gensidighed mellem de deltagende parter, og konceptet har de senere år har været...

  14. What constitutes information integrity?

    Directory of Open Access Journals (Sweden)

    S. Flowerday

    2008-01-01

    Full Text Available This research focused on what constitutes information integrity as this is a problem facing companies today. Moreover, information integrity is a pillar of information security and is required in order to have a sound security management programme. However, it is acknowledged that 100% information integrity is not currently achievable due to various limitations and therefore the auditing concept of reasonable assurance is adopted. This is in line with the concept that 100% information security is not achievable and the notion that adequate security is the goal, using appropriate countermeasures. The main contribution of this article is to illustrate the importance of and provide a macro view of what constitutes information integrity. The findings are in harmony with Samuel Johnson's words (1751: 'Integrity without knowledge is weak and useless, and knowledge without integrity is dangerous and dreadful.'

  15. The backbone of the post-synaptic density originated in a unicellular ancestor of choanoflagellates and metazoans

    Directory of Open Access Journals (Sweden)

    Manuel Michaël

    2010-02-01

    Full Text Available Abstract Background Comparative genomics of the early diverging metazoan lineages and of their unicellular sister-groups opens new window to reconstructing the genetic changes which preceded or accompanied the evolution of multicellular body plans. A recent analysis found that the genome of the nerve-less sponges encodes the homologues of most vertebrate post-synaptic proteins. In vertebrate excitatory synapses, these proteins assemble to form the post-synaptic density, a complex molecular platform linking membrane receptors, components of their signalling pathways, and the cytoskeleton. Newly available genomes from Monosiga brevicollis (a member of Choanoflagellata, the closest unicellular relatives of animals and Trichoplax adhaerens (a member of Placozoa: besides sponges, the only nerve-less metazoans offer an opportunity to refine our understanding of post-synaptic protein evolution. Results Searches for orthologous proteins and reconstruction of gene gains/losses based on the taxon phylogeny indicate that post-synaptic proteins originated in two main steps. The backbone scaffold proteins (Shank, Homer, DLG and some of their partners were acquired in a unicellular ancestor of choanoflagellates and metazoans. A substantial additional set appeared in an exclusive ancestor of the Metazoa. The placozoan genome contains most post-synaptic genes but lacks some of them. Notably, the master-scaffold protein Shank might have been lost secondarily in the placozoan lineage. Conclusions The time of origination of most post-synaptic proteins was not concomitant with the acquisition of synapses or neural-like cells. The backbone of the scaffold emerged in a unicellular context and was probably not involved in cell-cell communication. Based on the reconstructed protein composition and potential interactions, its ancestral function could have been to link calcium signalling and cytoskeleton regulation. The complex later became integrated into the evolving

  16. The Constitution in Other Lands.

    Science.gov (United States)

    Bill of Rights in Action, 1987

    1987-01-01

    Designed for classroom teaching, this document contains articles on the new constitutions of Japan, South Korea, and the Philippine Islands which were modeled in part on the U.S. Constitution. These countries' experiences with constitutional government are examined, and whether or not the U.S. Constitution can be a suitable model for other…

  17. The "alternative" choice of constitutive exons throughout evolution.

    Directory of Open Access Journals (Sweden)

    Galit Lev-Maor

    2007-11-01

    Full Text Available Alternative cassette exons are known to originate from two processes-exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution. We compiled a dataset of orthologous exons from human and mouse that are constitutively spliced in one species but alternatively spliced in the other. Examination of these exons suggests that the common ancestors were constitutively spliced. We show that relaxation of the 5' splice site during evolution is one of the molecular mechanisms by which exons shift from constitutive to alternative splicing. This shift is associated with the fixation of exonic splicing regulatory sequences (ESRs that are essential for exon definition and control the inclusion level only after the transition to alternative splicing. The effect of each ESR on splicing and the combinatorial effects between two ESRs are conserved from fish to human. Our results uncover an evolutionary pathway that increases transcriptome diversity by shifting exons from constitutive to alternative splicing.

  18. Effect of reference population size and available ancestor genotypes on imputation of Mexican Holstein genotypes

    Science.gov (United States)

    The effects of reference population size and the availability of information from genotyped ancestors on the accuracy of imputation of single nucleotide polymorphisms (SNPs) were investigated for Mexican Holstein cattle. Three scenarios for reference population size were examined: (1) a local popula...

  19. Graves, Ancestors and Cement in Land disputes in Acholi and Ikland, Uganda

    DEFF Research Database (Denmark)

    Meinert, Lotte; Willerslev, Rane; Seebach, Sophie Hooge

    2017-01-01

    The paper explores the roles of graves, ancestors and concrete pillars in disputes over land across different land-systems, -conflicts, and territory making in northern Uganda by comparing extended cases between Acholi in Gulu district and Ik in Kaabong district . In the post-conflict Acholi region...

  20. Integration of Morphological Data into Molecular Phylogenetic Analysis: Toward the Identikit of the Stylasterid Ancestor

    Science.gov (United States)

    Puce, Stefania; Pica, Daniela; Schiaparelli, Stefano; Negrisolo, Enrico

    2016-01-01

    Stylasteridae is a hydroid family including 29 worldwide-distributed genera, all provided with a calcareous skeleton. They are abundant in shallow and deep waters and represent an important component of marine communities. In the present paper, we studied the evolution of ten morphological characters, currently used in stylasterid taxonomy, using a phylogenetic approach. Our results indicate that stylasterid morphology is highly plastic and that many events of independent evolution and reversion have occurred. Our analysis also allows sketching a possible identikit of the stylasterid ancestor. It had calcareous skeleton, reticulate-granular coenosteal texture, polyps randomly arranged, gastrostyle, and dactylopore spines, while lacking a gastropore lip and dactylostyles. If the ancestor had single or double/multiple chambered gastropore tube is uncertain. These data suggest that the ancestor was similar to the extant genera Cyclohelia and Stellapora. Our investigation is the first attempt to integrate molecular and morphological information to clarify the stylasterid evolutionary scenario and represents the first step to infer the stylasterid ancestor morphology. PMID:27537333

  1. Combining information from ancestors and personal experiences to predict individual differences in developmental trajectories.

    Science.gov (United States)

    Stamps, Judy A; Krishnan, V V

    2014-11-01

    A persistent question in biology is how information from ancestors combines with personal experiences over the lifetime to affect the developmental trajectories of phenotypic traits. We address this question by modeling individual differences in behavioral developmental trajectories on the basis of two assumptions: (1) differences among individuals in the behavior expressed at birth or hatching are based on information from their ancestors (via genes, epigenes, and prenatal maternal effects), and (2) information from ancestors is combined with information from personal experiences over ontogeny via Bayesian updating. The model predicts relationships between the means and the variability of the behavior expressed by neonates and the subsequent developmental trajectories of their behavior when every individual is reared under the same environmental conditions. Several predictions of the model are supported by data from previous studies of behavioral development, for example, that the temporal stability of personality will increase with age and that the intercepts and slopes of developmental trajectories for boldness will be negatively correlated across individuals or genotypes when subjects are raised in safe environments. We describe how other specific predictions of the model can be used to test the hypothesis that information from ancestors and information from personal experiences are combined via nonadditive, Bayesian-like processes.

  2. Sulfated polysaccharides from marine sponges (Porifera): an ancestor cell-cell adhesion event based on the carbohydrate-carbohydrate interaction.

    Science.gov (United States)

    Vilanova, Eduardo; Coutinho, Cristiano C; Mourão, Paulo A S

    2009-08-01

    Marine sponges (Porifera) are ancient and simple eumetazoans. They constitute key organisms in the evolution from unicellular to multicellular animals. We now demonstrated that pure sulfated polysaccharides from marine sponges are responsible for the species-specific cell-cell interaction in these invertebrates. This conclusion was based on the following observations: (1) each species of marine sponge has a single population of sulfated polysaccharide, which differ among the species in their sugar composition and sulfate content; (2) sulfated polysaccharides from sponge interact with each other in a species-specific way, as indicated by an affinity chromatography assay, and this interaction requires calcium; (3) homologous, but not heterologous, sulfated polysaccharide inhibits aggregation of dissociated sponge cells; (4) we also observed a parallel between synthesis of the sulfated polysaccharide and formation of large aggregates of sponge cells, known as primmorphs. Once aggregation reached a plateau, the demand for the de novo synthesis of sulfated polysaccharides ceased. Heparin can mimic the homologous sulfated polysaccharide on the in vitro interaction and also as an inhibitor of aggregation of the dissociated sponge cells. However, this observation is not relevant for the biology of the sponge since heparin is not found in the invertebrate. In conclusion, marine sponges display an ancestor event of cell-cell adhesion, based on the calcium-dependent carbohydrate-carbohydrate interaction.

  3. Constitution, 5 May 1989.

    Science.gov (United States)

    1989-01-01

    This document contains provisions of Cambodia's Constitution of May 5, 1989. Article 7 gives men and women equal rights in marriage and the family, calls for monogamous marriages, and affords social protection to mothers and children. Article 8 guides parent-child relationships. The 14th article defines state property, and the 15th gives citizens full rights to own, use, and inherit land. The use of agricultural and forested land can only be changed with permission. Article 22 assigns educational responsibilities to the state, including free elementary education and a gradual expansion of higher education. Adult literacy classes are also promoted. Article 26 guarantees free medical consultations, and article 27 gives women a 90-day paid maternity leave. Breast-feeding women are also given special privileges. Article 33 guarantees the right to pay equity and to social security benefits. Article 36 grants the freedom to travel, the inviolability of homes, and privacy in correspondence of all types.

  4. Constitutive models in LAME.

    Energy Technology Data Exchange (ETDEWEB)

    Hammerand, Daniel Carl; Scherzinger, William Mark

    2007-09-01

    The Library of Advanced Materials for Engineering (LAME) provides a common repository for constitutive models that can be used in computational solid mechanics codes. A number of models including both hypoelastic (rate) and hyperelastic (total strain) constitutive forms have been implemented in LAME. The structure and testing of LAME is described in Scherzinger and Hammerand ([3] and [4]). The purpose of the present report is to describe the material models which have already been implemented into LAME. The descriptions are designed to give useful information to both analysts and code developers. Thus far, 33 non-ITAR/non-CRADA protected material models have been incorporated. These include everything from the simple isotropic linear elastic models to a number of elastic-plastic models for metals to models for honeycomb, foams, potting epoxies and rubber. A complete description of each model is outside the scope of the current report. Rather, the aim here is to delineate the properties, state variables, functions, and methods for each model. However, a brief description of some of the constitutive details is provided for a number of the material models. Where appropriate, the SAND reports available for each model have been cited. Many models have state variable aliases for some or all of their state variables. These alias names can be used for outputting desired quantities. The state variable aliases available for results output have been listed in this report. However, not all models use these aliases. For those models, no state variable names are listed. Nevertheless, the number of state variables employed by each model is always given. Currently, there are four possible functions for a material model. This report lists which of these four methods are employed in each material model. As far as analysts are concerned, this information is included only for the awareness purposes. The analyst can take confidence in the fact that model has been properly implemented

  5. Is Ancestor veneration the most universal of all world religions? A critique of modernist cosmological bias

    Directory of Open Access Journals (Sweden)

    Thomas Reuter

    2015-07-01

    Full Text Available Research by anthropologists engaged with the Comparative Austronesia Project (Australian National University has amassed an enormous data set for ethnological comparison between the religions of Austronesian-speaking societies, a language group to which nearly all Indonesian societies also belong. Comparative analysis reveals that ancestor veneration is a key-shared feature among “Austronesian” religious cosmologies; a feature that also resonates strongly with the ancestor-focused religions characteristic of East Asia. Characteristically, the religions of Austronesian-speaking societies focus on the core idea of a sacred time and place of ancestral origin and the continuous flow of life that is issuing forth from this source. Present-day individuals connect with the place and time of origin though ritual acts of retracing a historical path of migration to its source. What can this seemingly exotic notion of a flow of life reveal about the human condition writ large? Is it merely a curiosity of the ethnographic record of this region, a traditional religious insight forgotten even by many of the people whose traditional religion this is, but who have come under the influence of so-called world religions? Or is there something of great importance to be learnt from the Austronesian approach to life? Such questions have remained unasked until now, I argue, because a systematic cosmological bias within western thought has largely prevented us from taking Ancestor Religion and other forms of “traditional knowledge” seriously as an alternative truth claim. While I have discussed elsewhere the significance of Ancestor Religion in reference to my own research in highland Bali, I will attempt in this paper to remove this bias by its roots. I do so by contrasting two modes of thought: the “incremental dualism” of precedence characteristic of Austronesian cultures and their Ancestor Religions, and the “transcendental dualism” of mind and

  6. The diffusion of constitutional rights

    NARCIS (Netherlands)

    Goderis, B.V.G.; Versteeg, M.

    2014-01-01

    Constitutions are commonly regarded as uniquely national products, shaped by domestic ideals and politics. This paper develops and empirically investigates a novel hypothesis, which is that constitutions are also shaped by transnational influence, or “diffusion.” Constitutional rights can diffuse th

  7. Development of ancestors' cultivation revealed in phytolith assemblages from Guangfulin relics

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Shanghai Museum has got great achievements in re-excavating Guangfulin relics. It is the first time that the cultural remains of Wangyoufang type is found above the Liangzhu cultural remains which comes from East Henan Province, providing previous materials for researching culture evolution around Taihu Lake. Samples were taken from the immature soil layer and cultural layers of Guangfulin relics for phytolith analysis. According to the systemic research for the archaeological remains and phytolith fossil, the phytoliths in Guangfulin relics can be divided into four zones. The development of rice agriculture and living condition of Guangfulin ancestors was discussed based on the existing rice fan-shaped phytolith, rice shell phytolith, diatom fossil and archaeology evidence in the same layer. The Guangfulin relics has gradually developed since a high sea level 5000 years ago, and the broad rice agriculture has simultaneously developed. The newly re-excavated relics provides valuable materials for the research of ancestors and ancient culture in Shanghai.

  8. Constitution, 1989. [Selected provisions].

    Science.gov (United States)

    1989-01-01

    Chapter XII of the Hungarian Constitution, 1989, details the Fundamental Rights and Duties of Citizens. Everyone lawfully within the territory of Hungary has the right to liberty of movement and the freedom to choose his or her residence, except when restricted by law, including the right to leave his or her residence or county. The Republic of Hungary grants asylum to foreign citizens who were persecuted for racial, religious ethnic, linguistic, or political reasons. Men and women shall equally enjoy all civil, political, economic, social and political rights. Mothers are entitled to special care and protection before and after childbirth; women and juveniles are protected at work by special regulations. Every child has the right to special care an assistance from his or her family, the State, and society, for appropriate physical, spiritual, and moral development. Parents shall decide the kind of education their children receive. Hungary grants equal rights to all person within its territories, without regard to race, color, sex, language, religion, political, or other opinion, national, and social origin, property, birth and other status. Prejudicial discrimination shall be severely punished. Everyone has the right to work, to the free choice of employment and profession and to equal pay for equal work. Citizens have the right to social security, including social services necessary in old age, sickness, disability, widowhood, orphanhood an unemployment through no fault of their own. Hungary guarantees the right to culture for its citizens and realized this right by free and compulsory elementary education, by secondary and higher education which is accessible to all on the basis of capacity, and by the financial support of those receiving an education.

  9. Emergence and Evolution

    DEFF Research Database (Denmark)

    Bullwinkle, Tammy J; Ibba, Michael

    2013-01-01

    ancestor and as such they provide insights into the evolution and development of the extant genetic code. Although the aaRSs have long been viewed as a highly conserved group of enzymes, findings within the last couple of decades have started to demonstrate how diverse and versatile these enzymes really...... are. Beyond their central role in translation, aaRSs and their numerous homologs have evolved a wide array of alternative functions both inside and outside translation. Current understanding of the emergence of the aaRSs, and their subsequent evolution into a functionally diverse enzyme family...

  10. The Competence Constitution of Entrepreneurs in Emerging Industries%新兴产业创业企业家的胜任力结构解析--基于跨案例分析法

    Institute of Scientific and Technical Information of China (English)

    黄永春; 雷砺颖

    2016-01-01

    The industrialization of China's emerging technologies is faced with the 'Sea of Darwin', which urgently requires entrepreneurs to unearth entrepreneurial opportunities and integrate innovation resources to promote the re-form and commercialization of such technologies. Based on the competency theory, this paper establishes the ana-lytical framework for the competency of entrepreneurs in emerging industries, makes use of the cross-case study method to compare the architectural features of competency of the three entrepreneurs Jack Ma, Pony Ma, and Robin Li, probes into the general and heterogeneous characteristics of competency composition among entrepre-neurs in emerging industries, and then discusses the internal relationship between entrepreneurs' competency archi-tecture and their entrepreneurial mode selection. Research findings are as follows: (1) The competencies of entre-preneurs in emerging industries are mainly composed of meta-competency, cognitive competency, personal compe-tency, functional competency, and values, and the competency architecture of entrepreneurs is heterogeneous. (2) The difference in the competency architecture of entrepreneurs in emerging industries not only prevents entrepre-neurs from exploring entrepreneurial opportunities, but also hinders entrepreneurs' integrated use of entrepreneurial resources, thus affecting their selection of the entrepreneurial mode. (3) Entrepreneurs who are capable of accurate-ly judging market trends, good at seizing market opportunities and able to efficiently integrate market resources prefer to select the entrepreneurial mode oriented by business mode reform, while those who have priori know-ledge of technology research and development, are good at catching technology entrepreneurship opportunities and keen on promoting technological change and transformation usually select the entrepreneurial mode oriented by technological paradigm reform.%中国新兴技术的产业化面临达尔文之海,亟

  11. Mitochondria, the Cell Cycle, and the Origin of Sex via a Syncytial Eukaryote Common Ancestor.

    Science.gov (United States)

    Garg, Sriram G; Martin, William F

    2016-07-02

    Theories for the origin of sex traditionally start with an asexual mitosing cell and add recombination, thereby deriving meiosis from mitosis. Though sex was clearly present in the eukaryote common ancestor, the order of events linking the origin of sex and the origin of mitosis is unknown. Here, we present an evolutionary inference for the origin of sex starting with a bacterial ancestor of mitochondria in the cytosol of its archaeal host. We posit that symbiotic association led to the origin of mitochondria and gene transfer to host's genome, generating a nucleus and a dedicated translational compartment, the eukaryotic cytosol, in which-by virtue of mitochondria-metabolic energy was not limiting. Spontaneous protein aggregation (monomer polymerization) and Adenosine Tri-phosphate (ATP)-dependent macromolecular movement in the cytosol thereby became selectable, giving rise to continuous microtubule-dependent chromosome separation (reduction division). We propose that eukaryotic chromosome division arose in a filamentous, syncytial, multinucleated ancestor, in which nuclei with insufficient chromosome numbers could complement each other through mRNA in the cytosol and generate new chromosome combinations through karyogamy. A syncytial (or coenocytic, a synonym) eukaryote ancestor, or Coeca, would account for the observation that the process of eukaryotic chromosome separation is more conserved than the process of eukaryotic cell division. The first progeny of such a syncytial ancestor were likely equivalent to meiospores, released into the environment by the host's vesicle secretion machinery. The natural ability of archaea (the host) to fuse and recombine brought forth reciprocal recombination among fusing (syngamy and karyogamy) progeny-sex-in an ancestrally meiotic cell cycle, from which the simpler haploid and diploid mitotic cell cycles arose. The origin of eukaryotes was the origin of vertical lineage inheritance, and sex was required to keep vertically

  12. Emerging images

    KAUST Repository

    Mitra, Niloy J.

    2009-01-01

    Emergence refers to the unique human ability to aggregate information from seemingly meaningless pieces, and to perceive a whole that is meaningful. This special skill of humans can constitute an effective scheme to tell humans and machines apart. This paper presents a synthesis technique to generate images of 3D objects that are detectable by humans, but difficult for an automatic algorithm to recognize. The technique allows generating an infinite number of images with emerging figures. Our algorithm is designed so that locally the synthesized images divulge little useful information or cues to assist any segmentation or recognition procedure. Therefore, as we demonstrate, computer vision algorithms are incapable of effectively processing such images. However, when a human observer is presented with an emergence image, synthesized using an object she is familiar with, the figure emerges when observed as a whole. We can control the difficulty level of perceiving the emergence effect through a limited set of parameters. A procedure that synthesizes emergence images can be an effective tool for exploring and understanding the factors affecting computer vision techniques. © 2009 ACM.

  13. One ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylation

    Directory of Open Access Journals (Sweden)

    Szathmáry Eörs

    2009-01-01

    Full Text Available Abstract Background The genetic code is brought into action by 20 aminoacyl-tRNA synthetases. These enzymes are evenly divided into two classes (I and II that recognize tRNAs from the minor and major groove sides of the acceptor stem, respectively. We have reported recently that: (1 ribozymic precursors of the synthetases seem to have used the same two sterically mirror modes of tRNA recognition, (2 having these two modes might have helped in preventing erroneous aminoacylation of ancestral tRNAs with complementary anticodons, yet (3 the risk of confusion for the presumably earliest pairs of complementarily encoded amino acids had little to do with anticodons. Accordingly, in this communication we focus on the acceptor stem. Results Our main result is the emergence of a palindrome structure for the acceptor stem's common ancestor, reconstructed from the phylogenetic trees of Bacteria, Archaea and Eukarya. In parallel, for pairs of ancestral tRNAs with complementary anticodons, we present updated evidence of concerted complementarity of the second bases in the acceptor stems. These two results suggest that the first pairs of "complementary" amino acids that were engaged in primordial coding, such as Gly and Ala, could have avoided erroneous aminoacylation if and only if the acceptor stems of their adaptors were recognized from the same, major groove, side. The class II protein synthetases then inherited this "primary preference" from isofunctional ribozymes. Conclusion Taken together, our results support the hypothesis that the genetic code per se (the one associated with the anticodons and the operational code of aminoacylation (associated with the acceptor diverged from a common ancestor that probably began developing before translation. The primordial advantage of linking some amino acids (most likely glycine and alanine to the ancestral acceptor stem may have been selective retention in a protocell surrounded by a leaky membrane for use in

  14. The Political Economy of Constitution

    OpenAIRE

    Pabst, Adrian

    2016-01-01

    The distinction between constitution, as the set of fundamental normative premises ensuring the cohesion of any given polity, and contract, as the formal covenant agreed upon by the relevant stakeholders in that polity, is central to political economy. This paper outlines a conceptual framework for the political economy of constitution based on the above distinction. Our argument is that constitution in the material sense, that is, as a relatively stable configuration of interests prior to fo...

  15. Constitutional Issues--Watergate and the Constitution. Teaching with Documents.

    Science.gov (United States)

    National Archives and Records Administration, Washington, DC.

    When U.S. President Richard Nixon resigned in 1974 in the wake of the Watergate scandal, it was only the second time that impeachment of a president had been considered. Although the U.S. Constitution has provisions for a person removed from office to be indicted, there are no guidelines in the Constitution about a President who has resigned. The…

  16. The Spanish Constitution, the Constitutional Court and the Catalan Referendum

    DEFF Research Database (Denmark)

    Abat Ninet, Antoni

    2015-01-01

    This chapter deals with a core topic in constitutional law, that of the conflict between constitutions and will of the demos. Aristotle in Book IV of the Politics had already anticipated the possible conflict between these two forms of Politeia (constitutions), when defining the types of democracy....... He also distinguished the role that the Nomophylakes (guardians of the laws) should play in this sort of anticipated conflict after what Madison v. Marbury called had globally referred to it around the world as “judicial review”. But the concept of a constitution as a form of government......; and as a document that organised the offices of a state changed through the history. The Magna Carta, the French and American revolutionaries provided gave the concept a new meaning to the concept. After these historical episodes, constitutions were not simply political or legal norms to knowshowing how to play...

  17. Constitutional Law and Liberal Education.

    Science.gov (United States)

    Clor, Harry

    1985-01-01

    By studying constitutional law, students learn about the relationship between democratic theory and practice, one of the main concerns of liberal education. The mind is enlarged when it must apply ethical standards and political ideas to real human problems. How a political science professor teaches constitutional law is discussed. (RM)

  18. Reordering American Constitutional Law Teaching.

    Science.gov (United States)

    Gerber, Scott D.

    1994-01-01

    Maintains that constitutional law is the cornerstone of an undergraduate public law curriculum. Asserts that there is a welcome trend toward teaching the subject over a two-semester sequence, instead of only one. Describes course content and teaching strategies used in a college constitutional law course. (CFR)

  19. The Constitution and Its Critics

    Science.gov (United States)

    Main, Thomas J.

    2011-01-01

    In planning a freshman undergraduate curriculum with colleagues recently, the question arose as to what type of understanding educators wanted to impart to their students about the Constitution. The alleged defects of the Constitution that these books point to are wide-ranging and can be classified into various categories. Some problems--such as…

  20. Comparing salt tolerance of beet cultivars and their halophytic ancestor: consequences of domestication and breeding programmes.

    Science.gov (United States)

    Rozema, Jelte; Cornelisse, Danny; Zhang, Yuancheng; Li, Hongxiu; Bruning, Bas; Katschnig, Diana; Broekman, Rob; Ji, Bin; van Bodegom, Peter

    2014-12-09

    Salt tolerance of higher plants is determined by a complex set of traits, the timing and rate of evolution of which are largely unknown. We compared the salt tolerance of cultivars of sugar beet and their ancestor, sea beet, in hydroponic studies and evaluated whether traditional domestication and more recent breeding have changed salt tolerance of the cultivars relative to their ancestor. Our comparison of salt tolerance of crop cultivars is based on values of the relative growth rate (RGR) of the entire plant at various salinity levels. We found considerable salt tolerance of the sea beet and slightly, but significantly, reduced salt tolerance of the sugar beet cultivars. This indicates that traditional domestication by selection for morphological traits such as leaf size, beet shape and size, enhanced productivity, sugar content and palatability slightly affected salt tolerance of sugar beet cultivars. Salt tolerance among four sugar beet cultivars, three of which have been claimed to be salt tolerant, did not differ. We analysed the components of RGR to understand the mechanism of salt tolerance at the whole-plant level. The growth rate reduction at higher salinity was linked with reduced leaf area at the whole-plant level (leaf area ratio) and at the individual leaf level (specific leaf area). The leaf weight fraction was not affected by increased salinity. On the other hand, succulence and leaf thickness and the net assimilation per unit of leaf area (unit leaf rate) increased in response to salt treatment, thus partially counteracting reduced capture of light by lower leaf area. This compensatory mechanism may form part of the salt tolerance mechanism of sea beet and the four studied sugar beet cultivars. Together, our results indicate that domestication of the halophytic ancestor sea beet slightly reduced salt tolerance and that breeding for improved salt tolerance of sugar beet cultivars has not been effective.

  1. Ancestor-descendant relationships in evolution: origin of the extant pygmy right whale, Caperea marginata.

    Science.gov (United States)

    Tsai, Cheng-Hsiu; Fordyce, R Ewan

    2015-01-01

    Ancestor-descendant relationships (ADRs), involving descent with modification, are the fundamental concept in evolution, but are usually difficult to recognize. We examined the cladistic relationship between the only reported fossil pygmy right whale, †Miocaperea pulchra, and its sole living relative, the enigmatic pygmy right whale Caperea marginata, the latter represented by both adult and juvenile specimens. †Miocaperea is phylogenetically bracketed between juvenile and adult Caperea marginata in morphologically based analyses, thus suggesting a possible ADR-the first so far identified within baleen whales (Cetacea: Mysticeti). The †Miocaperea-Caperea lineage may show long-term morphological stasis and, in turn, punctuated equilibrium.

  2. Evidence for a single loss of mineralized teeth in the common avian ancestor

    DEFF Research Database (Denmark)

    Meredith, Robert W.; Zhang, Guojie; Gilbert, M. Thomas P.

    2014-01-01

    Edentulism, the absence of teeth, has evolved convergently among vertebrates, including birds, turtles, and several lineages of mammals. Instead of teeth, modern birds (Neornithes) use a horny beak (rhamphotheca) and a muscular gizzard to acquire and process food.We performed comparative genomic...... analyses representing lineages of nearly all extant bird orders and recovered shared, inactivating mutations within genes expressed in both the enamel and dentin of teeth of other vertebrate species, indicating that the common ancestor of modern birds lacked mineralized teeth.We estimate that tooth loss......, or at least the loss of enamel caps that provide the outer layer of mineralized teeth, occurred about 116 million years ago....

  3. Evidence of duplicated Hox genes in the most recent common ancestor of extant scorpions.

    Science.gov (United States)

    Sharma, Prashant P; Santiago, Marc A; González-Santillán, Edmundo; Monod, Lionel; Wheeler, Ward C

    2015-01-01

    Scorpions (order Scorpiones) are unusual among arthropods, both for the extreme heteronomy of their bauplan and for the high gene family turnover exhibited in their genomes. These phenomena appear to be correlated, as two scorpion species have been shown to possess nearly twice the number of Hox genes present in most arthropods. Segmentally offset anterior expression boundaries of a subset of Hox paralogs have been shown to correspond to transitions in segmental identities in the scorpion posterior tagmata, suggesting that posterior heteronomy in scorpions may have been achieved by neofunctionalization of Hox paralogs. However, both the first scorpion genome sequenced and the developmental genetic data are based on exemplars of Buthidae, one of 19 families of scorpions. It is therefore not known whether Hox paralogy is limited to Buthidae or widespread among scorpions. We surveyed 24 high throughput transcriptomes and the single whole genome available for scorpions, in order to test the prediction that Hox gene duplications are common to the order. We used gene tree parsimony to infer whether the paralogy was consistent with a duplication event in the scorpion common ancestor. Here we show that duplicated Hox genes in non-buthid scorpions occur in six of the ten Hox classes. Gene tree topologies and parsimony-based reconciliation of the gene trees are consistent with a duplication event in the most recent common ancestor of scorpions. These results suggest that a Hox paralogy, and by extension the model of posterior patterning established in a buthid, can be extended to non-Buthidae scorpions.

  4. Pseudogenization of the tooth gene enamelysin (MMP20) in the common ancestor of extant baleen whales.

    Science.gov (United States)

    Meredith, Robert W; Gatesy, John; Cheng, Joyce; Springer, Mark S

    2011-04-07

    Whales in the suborder Mysticeti are filter feeders that use baleen to sift zooplankton and small fish from ocean waters. Adult mysticetes lack teeth, although tooth buds are present in foetal stages. Cladistic analyses suggest that functional teeth were lost in the common ancestor of crown-group Mysticeti. DNA sequences for the tooth-specific genes, ameloblastin (AMBN), enamelin (ENAM) and amelogenin (AMEL), have frameshift mutations and/or stop codons in this taxon, but none of these molecular cavities are shared by all extant mysticetes. Here, we provide the first evidence for pseudogenization of a tooth gene, enamelysin (MMP20), in the common ancestor of living baleen whales. Specifically, pseudogenization resulted from the insertion of a CHR-2 SINE retroposon in exon 2 of MMP20. Genomic and palaeontological data now provide congruent support for the loss of enamel-capped teeth on the common ancestral branch of crown-group mysticetes. The new data for MMP20 also document a polymorphic stop codon in exon 2 of the pygmy sperm whale (Kogia breviceps), which has enamel-less teeth. These results, in conjunction with the evidence for pseudogenization of MMP20 in Hoffmann's two-toed sloth (Choloepus hoffmanni), another enamel-less species, support the hypothesis that the only unique, non-overlapping function of the MMP20 gene is in enamel formation.

  5. New Constitutionalism for Biosiversity vs. Neoconstitutionalism of Risk

    Directory of Open Access Journals (Sweden)

    Michele Carducci

    2016-08-01

    Full Text Available http://dx.doi.org/10.5007/2177-7055.2016v37n73p255 Based on an “eco-systemic” democracy that seeks to preserve biodiversity through the recognition of the co-evolutionary link between nature and culture, the Andean Constitutionalism emerges as the expression of a counter-hegemonic constitutionalism committed to the construction of a new institutional framework through the inclusion of new participatory and intercultural mechanisms. Departing from western constitutional paradigms, this groundbreaking constitutionalism revisits the “Gaia hypothesis” and legitimizes a real “social contract” among the people and nature, and instead of considering it as an “object” of ownership, exploitation, or conservation, it regards nature as a legal “subject” and primary source of society itself and the Constitution as its “legal grantor and protector”.

  6. Constitutive Modelling in Geomechanics Introduction

    CERN Document Server

    Puzrin, Alexander M

    2012-01-01

    The purpose of this book is to bridge the gap between the traditional Geomechanics and Numerical Geotechnical Modelling with applications in science and practice. Geomechanics is rarely taught within the rigorous context of Continuum Mechanics and Thermodynamics, while when it comes to Numerical Modelling, commercially available finite elements or finite differences software utilize constitutive relationships within the rigorous framework. As a result, young scientists and engineers have to learn the challenging subject of constitutive modelling from a program manual and often end up with using unrealistic models which violate the Laws of Thermodynamics.  The book is introductory, by no means does it claim any completeness and state of the art in such a dynamically developing field as numerical and constitutive modelling of soils. The author gives basic understanding of conventional continuum mechanics approaches to constitutive modelling, which can serve as a foundation for exploring more advanced theories....

  7. The significance of constitutional values

    Directory of Open Access Journals (Sweden)

    HN Nisihara

    2001-12-01

    Full Text Available This article addresses the question of the meaning and legal significance of constitutional values in contemporary times. The article attends also to related questions namely, what constituteconstitutional values” and what are the limitations of the meaning afforded to this notion. Attention is paid in the particular, to freedom, equality and democracy as value-neutral criteria of fairness and government neutrality with reference to the South African and German contexts as well as to value-neutrality as a culturally conditioned value. The author concludes with a cosmopolitan view of freedom and the right to peace with reference to the constitutional texts of Japan and the United States.

  8. Are Sanctions on Employers Constitutional?

    Science.gov (United States)

    Gollobin, Ira

    1988-01-01

    Questions the constitutional validity of employer sanctions used to deter illegal immigration under the Immigration Reform and Control Act. Points out the anomaly of using criminal penalties to deter a civil, administrative violation. (FMW)

  9. Constitutional Verbosity and Social Trust

    DEFF Research Database (Denmark)

    Bjørnskov, Christian; Voigt, Stefan

    2014-01-01

    A common argument in the trust literature is that high-trust cultures allow efficient commercial contracts to be shorter, covering fewer contingencies. We take this idea to the topic of social contracts. Specifically, we ask whether social trust affects the length and detail of constitutions. Cross......-country estimates suggest that national trust levels are indeed robustly and negatively associated with the length of countries’ constitutions....

  10. Does Homeland Security Constitute an Emerging Academic Discipline?

    Science.gov (United States)

    2013-03-01

    disciplines that make it easy for them to find a job and receive good pay. 7. Entrepreneurs will enter and firms will expand in sectors that promise to be...publication 12. Percent female students 3. Percent faculty with grants 13. Percent international students 4. Awards per allocated faculty member 14...time to degree 7. Percent female faculty 17. Percent students with academic plans 8. Average GRE scores 18. Student work space 9. Percent 1st-yr

  11. STABILITY AND CONSTITUTIONAL REFORM NORMATIVE CONTENTS OF CONSTITUTION

    Directory of Open Access Journals (Sweden)

    Marius ANDREESCU

    2016-05-01

    Full Text Available The modification of the fundamental law of a state represents a very special political and juridical act with major significances and implications in the political social system as in the state’s one, but also at each individual level. That’s why such an approach needs to be well justified, to answer to some juridical and political social needs well defined, but mainly to correspond to the principles and rules specific to a constitutional and state’s democratic system providing to the state the stability and functionality it needs. In this study we analyze the necessity of such a constitutional reform in Romania, and also some provisions from the report of the Presidential Commission for the analysis of the political and constitutional regime in our country. We formulate our opinions in relation to the justifying some constitutional regulations. In this context, we consider that there are arguments for the maintaining of the bicameral parliamentary system and an eventual revising of the fundamental law needs to consider the measures needed to guarantee the political and constitutional institutions specific to the lawful state.

  12. Turkish and Japanese Mycobacterium tuberculosis sublineages share a remote common ancestor

    KAUST Repository

    Refregier, Guislaine

    2016-10-14

    Two geographically distant M. tuberculosis sublineages, Tur from Turkey and T3-Osaka from Japan, exhibit partially identical genotypic signatures (identical 12-loci MIRU-VNTR profiles, distinct spoligotyping patterns). We investigated T3-Osaka and Tur sublineages characteristics and potential genetic relatedness, first using MIRU-VNTR locus analysis on 21 and 25 samples of each sublineage respectively, and second comparing Whole Genome Sequences of 8 new samples to public data from 45 samples uncovering human tuberculosis diversity. We then tried to date their Most Recent Common Ancestor (MRCA) using three calibrations of SNP accumulation rate (long-term = 0.03 SNP/genome/year, derived from a tuberculosis ancestor of around 70,000 years old; intermediate = 0.2 SNP/genome/year derived from a Peruvian mummy; short-term = 0.5 SNP/genome/year). To disentangle between these scenarios, we confronted the corresponding divergence times with major human history events and knowledge on human genetic divergence. We identified relatively high intrasublineage diversity for both T3-Osaka and Tur. We definitively proved their monophyly; the corresponding super-sublineage (referred to as “T3-Osa-Tur”) shares a common ancestor with T3-Ethiopia and Ural sublineages but is only remotely related to other Euro-American sublineages such as X, LAM, Haarlem and S. The evolutionary scenario based on long-term evolution rate being valid until T3-Osa-Tur MRCA was not supported by Japanese fossil data. The evolutionary scenario relying on short-term evolution rate since T3-Osa-Tur MRCA was contradicted by human history and potential traces of past epidemics. T3-Osaka and Tur sublineages were found likely to have diverged between 800 y and 2000 years ago, potentially at the time of Mongol Empire. Altogether, this study definitively proves a strong genetic link between Turkish and Japanese tuberculosis. It provides a first hypothesis for calibrating TB Euro-American lineage molecular clock

  13. Large number of ultraconserved elements were already present in the jawed vertebrate ancestor.

    KAUST Repository

    Wang, Jianli

    2009-03-01

    Stephen (2008) identified 13,736 ultraconserved elements (UCEs) in placental mammals and investigated their evolution in opossum, chicken, frog, and fugu. They found that there was a massive expansion of UCEs during tetrapod evolution and the substitution rate in UCEs showed a significant decline in tetrapods compared with fugu, suggesting they were exapted in tetrapods. They considered it unlikely that these elements are ancient but evolved at a higher rate in teleost fishes. In this study, we investigated the evolution of UCEs in a cartilaginous fish, the elephant shark and show that nearly half the UCEs were present in the jawed vertebrate ancestor. The substitution rate in UCEs is higher in fugu than in elephant shark, and approximately one-third of ancient UCEs have diverged beyond recognition in teleost fishes. These data indicate that UCEs have evolved at a higher rate in teleost fishes, which may have implications for their vast diversity and evolutionary success.

  14. The plastid ancestor originated among one of the major cyanobacterial lineages.

    Science.gov (United States)

    Ochoa de Alda, Jesús A G; Esteban, Rocío; Diago, María Luz; Houmard, Jean

    2014-09-15

    The primary endosymbiotic origin of chloroplasts is now well established but the identification of the present cyanobacteria most closely related to the plastid ancestor remains debated. We analyse the evolutionary trajectory of a subset of highly conserved cyanobacterial proteins (core) along the plastid lineage, those which were not lost after the endosymbiosis. We concatenate the sequences of 33 cyanobacterial core proteins that share a congruent evolutionary history, with their eukaryotic counterparts to reconstruct their phylogeny using sophisticated evolutionary models. We perform an independent reconstruction using concatenated 16S and 23S rRNA sequences. These complementary approaches converge to a plastid origin occurring during the divergence of one of the major cyanobacterial lineages that include N2-fixing filamentous cyanobacteria and species able to differentiate heterocysts.

  15. Origin and Evolution of Water Oxidation before the Last Common Ancestor of the Cyanobacteria.

    Science.gov (United States)

    Cardona, Tanai; Murray, James W; Rutherford, A William

    2015-05-01

    Photosystem II, the water oxidizing enzyme, altered the course of evolution by filling the atmosphere with oxygen. Here, we reconstruct the origin and evolution of water oxidation at an unprecedented level of detail by studying the phylogeny of all D1 subunits, the main protein coordinating the water oxidizing cluster (Mn4CaO5) of Photosystem II. We show that D1 exists in several forms making well-defined clades, some of which could have evolved before the origin of water oxidation and presenting many atypical characteristics. The most ancient form is found in the genome of Gloeobacter kilaueensis JS-1 and this has a C-terminus with a higher sequence identity to D2 than to any other D1. Two other groups of early evolving D1 correspond to those expressed under prolonged far-red illumination and in darkness. These atypical D1 forms are characterized by a dramatically different Mn4CaO5 binding site and a Photosystem II containing such a site may assemble an unconventional metal cluster. The first D1 forms with a full set of ligands to the Mn4CaO5 cluster are grouped with D1 proteins expressed only under low oxygen concentrations and the latest evolving form is the dominant type of D1 found in all cyanobacteria and plastids. In addition, we show that the plastid ancestor had a D1 more similar to those in early branching Synechococcus. We suggest each one of these forms of D1 originated from transitional forms at different stages toward the innovation and optimization of water oxidation before the last common ancestor of all known cyanobacteria.

  16. The Spanish Constitution, the Constitutional Court and the Catalan Referendum

    DEFF Research Database (Denmark)

    Abat Ninet, Antoni

    2015-01-01

    and politeia that Aristotle defined now clashes between two powerful symbolic and romantic phenomena. In the Spanish-Catalan binomial scenario, there are some elements that need to be analysed to obtain a complete picture of the constitutional possibilities to of accommodating a Catalan self...

  17. Time and constitution of sense

    Directory of Open Access Journals (Sweden)

    Pedro Gerardo Acosta

    2014-06-01

    Full Text Available This article proposes a reflection over our time-consciousness under the Phenomenology of Edmund Husserl. The idea is make a release the key role of the sense constitution like the fundament and development of the ongoing intentionality, a shape that make the possibility to catch sight of the sense of every life situation like conscience experience that displays itself over the time, and open the world of the Phenomenon World, constituted in the flux and flow of our live experience. The immanent time in which the things served in a lived-present inevitably displays to its own immediate-past of retentions, then of commemorations, constituting and enabling, not just the sense of ever present, but the sense of our own past like memory and our future like expectative. This reflection is based and supporter over the text “Phenomenology Lesson of the Internal Time-Consiusness” (Husserl, 2002.

  18. A Communicatively Constituted Online Crisis

    DEFF Research Database (Denmark)

    Valentini, Chiara; Romenti, Stefania; Kruckeberg, Dean

    2017-01-01

    into specific public crisis perceptions. Drawing from a communicative constitution perspective, the authors argue that if crises are perceptions or experiences of difficult situations that exceed a person’s current resources and coping mechanisms, and if perceptions and experiences in social media are typically...... mediated, then online crises and their meanings are communicatively constructed. The chapter outlines how online conversations constitute discursive practices that make publics aware of critical situations of which they may or may not know and can even construct reputational crises. The chapter concludes...... by offering suggestions on how to study online critical conversations through the lens of a communicative constitution perspective that could inform how critical issues eventually transform and become crises and how crisis perceptions evolve and are discursively shaped by communicative practices occurring...

  19. Locomotion and posture from the common hominoid ancestor to fully modern hominins, with special reference to the last common panin/hominin ancestor.

    Science.gov (United States)

    Crompton, R H; Vereecke, E E; Thorpe, S K S

    2008-04-01

    Based on our knowledge of locomotor biomechanics and ecology we predict the locomotion and posture of the last common ancestors of (a) great and lesser apes and their close fossil relatives (hominoids); (b) chimpanzees, bonobos and modern humans (hominines); and (c) modern humans and their fossil relatives (hominins). We evaluate our propositions against the fossil record in the context of a broader review of evolution of the locomotor system from the earliest hominoids of modern aspect (crown hominoids) to early modern Homo sapiens. While some early East African stem hominoids were pronograde, it appears that the adaptations which best characterize the crown hominoids are orthogrady and an ability to abduct the arm above the shoulder - rather than, as is often thought, manual suspension sensu stricto. At 7-9 Ma (not much earlier than the likely 4-8 Ma divergence date for panins and hominins, see Bradley, 2008) there were crown hominoids in southern Europe which were adapted to moving in an orthograde posture, supported primarily on the hindlimb, in an arboreal, and possibly for Oreopithecus, a terrestrial context. By 7 Ma, Sahelanthropus provides evidence of a Central African hominin, panin or possibly gorilline adapted to orthogrady, and both orthogrady and habitually highly extended postures of the hip are evident in the arboreal East African protohominin Orrorin at 6 Ma. If the traditional idea that hominins passed through a terrestrial 'knuckle-walking' phase is correct, not only does it have to be explained how a quadrupedal gait typified by flexed postures of the hindlimb could have preadapted the body for the hominin acquisition of straight-legged erect bipedality, but we would have to accept a transition from stem-hominoid pronogrady to crown hominoid orthogrady, back again to pronogrady in the African apes and then back to orthogrady in hominins. Hand-assisted arboreal bipedality, which is part of a continuum of orthograde behaviours, is used by modern

  20. Constitutional Analysis of Intellectual Property

    Directory of Open Access Journals (Sweden)

    AJ van der Walt

    2014-04-01

    Full Text Available This article analyses the Constitutional Court’s treatment of property interests in the face of state regulation to gain an understanding of the type of state interference that is justifiable in terms of section 25(1 of the Bill of Rights. This is done by examining the Constitutional Court’s dicta relating to the meaning of deprivation and how these inform the meaning of property in the constitutional context. The methodology that the Constitutional Court has formulated to assess if state interference complies with the provisions of section 25 is explained to show the type of state regulation that has been found legitimate. We then consider how this understanding of constitutional property and the state’s legitimate exercise of its inherent police power interact in the setting of intellectual property by contrasting the various policy objectives underlying the different statutory regimes governing intellectual property. This theoretical analysis is then applied to two contemporary examples of feasible state interference with existing intellectual property interests, namely the proposed plain packaging measures which severely restrict the use of tobacco trade marks, and a fair dealing exception allowing the use of copyright works for the purpose of parody. These examples serve to illustrate the context and manner in which intellectual property interests may come before the Court and the necessary differentiation with which these interests should be treated. The appropriate judicial assessment of the true impact that state action could have on vested property interests is explained and contrasted with the balancing exercise that is employed at the earlier stage of policy making. This discussion is concluded by highlighting some of the interpretational issues that will arise and how some constitutional values could be curtailed in the absence of legislative intervention.

  1. Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies.

    Directory of Open Access Journals (Sweden)

    Ben-Jiang Ma

    2011-09-01

    Full Text Available The HIV-1 gp41 envelope (Env membrane proximal external region (MPER is an important vaccine target that in rare subjects can elicit neutralizing antibodies. One mechanism proposed for rarity of MPER neutralizing antibody generation is lack of reverted unmutated ancestor (putative naive B cell receptor antibody reactivity with HIV-1 envelope. We have studied the effect of partial deglycosylation under non-denaturing (native conditions on gp140 Env antigenicity for MPER neutralizing antibodies and their reverted unmutated ancestor antibodies. We found that native deglycosylation of clade B JRFL gp140 as well as group M consensus gp140 Env CON-S selectively increased the reactivity of Env with the broad neutralizing human mAbs, 2F5 and 4E10. Whereas fully glycosylated gp140 Env either did not bind (JRFL, or weakly bound (CON-S, 2F5 and 4E10 reverted unmutated ancestors, natively deglycosylated JRFL and CON-S gp140 Envs did bind well to these putative mimics of naive B cell receptors. These data predict that partially deglycoslated Env would bind better than fully glycosylated Env to gp41-specific naïve B cells with improved immunogenicity. In this regard, immunization of rhesus macaques demonstrated enhanced immunogenicity of the 2F5 MPER epitope on deglyosylated JRFL gp140 compared to glycosylated JRFL gp140. Thus, the lack of 2F5 and 4E10 reverted unmutated ancestor binding to gp140 Env may not always be due to lack of unmutated ancestor antibody reactivity with gp41 peptide epitopes, but rather, may be due to glycan interference of binding of unmutated ancestor antibodies of broad neutralizing mAb to Env gp41.

  2. Towards a global climate constitution

    NARCIS (Netherlands)

    Weikard, H.P.

    2011-01-01

    In this paper my concern is the study of the incentives of individual countries to sign an international climate agreement that sets the terms of a climate constitution, that is, it establishes emission rights and rules for trading these rights to combat the climate problem effectively and efficient

  3. A Venture in Constitutional Law.

    Science.gov (United States)

    Cole, W. Graham; Dillon, Dorothy H.

    1980-01-01

    Senior high girls and boys from two single-sex schools undertook a study of a Supreme Court case that provided insight not only into constitutional law and history but also into how men and women can work together and relate in other ways than dating. (DS)

  4. The Constitutive Power of Twitter

    DEFF Research Database (Denmark)

    Albu, Oana Brindusa; Etter, Michael Andreas

    organizations. The analysis illustrates how specific Twitter interactions, i.e., hashtags, become hypertexts—a type of authoritative texts—which simultaneously constitute an organizational actor or act as a pastiche of it. The study contributes to extant research by illustrating how hypertextuality...

  5. Constitutional Change Marks Ideological Breakthrough

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    The amendments to the Constitution of the People'sRepublic of China, the fourth since the constitutionwas promulgated in 1982 and proposed by theCentral Committee of the Communist Party of China(CPC), are expected to enshrine the respect andprotection of human rights, the protection of private

  6. Take Advantage of Constitution Day

    Science.gov (United States)

    McCune, Bonnie F.

    2008-01-01

    The announcement of the mandate for Constitution and Citizenship Day shortly before September, 2005, probably led to groans of dismay. Not another "must-do" for teachers and schools already stressed by federal and state requirements for standardized tests, increasingly rigid curricula, and scrutiny from the public and officials. But the…

  7. Prospects of the Constitutional State of Indonesia: Ideas and Reality

    Directory of Open Access Journals (Sweden)

    Hamdan Zoelva

    2015-08-01

    Full Text Available Indonesia since its inception has asserted itself as a constitutional state. It may be inferred through the clear regulation related to powers and functions of each state institution in the form of checks and balances system, the protection of human rights, the clarity of the principles of democratic mechanism, as well as the guarantee of an independent judiciary. Although the constitution has been set in such a way, efforts to achieve a constitutional state is not an easy road. Nowadays, it seems that the trip of the Indonesian as a constitutional state was still hobbled. A variety of legal issues that disturb the sense of justice continues to emerge one after another. The outcomes of the research indicate that over the last decade, Indonesia has made many changes to realize the ideal of a constitutional state. As it turns out in practice, however, legal development was still far short from the expectations. The success of building a constitutional state can not be measured by the ability to produce legislation and to create or revitalize legal institutions. Moreover, the success of a constitutional state must also be measured by the implementation and law enforcement which able to create justice for all people. Therefore, the main focus of various studies of law and legal policy, must be oriented in the judicial institutions and law enforcement.

  8. Habermas on European Constitution and European Identity

    Directory of Open Access Journals (Sweden)

    Éva Biró-Kaszás

    2010-12-01

    Full Text Available For the last two decades or so philosophers have been reflecting on a set of practical and political concerns in connection with the new political structural arrangements beyond the nation-state. In this article two essays by Jürgen Habermas shall be examined. An attempt shall be made to tackle Habermas’ philosophical concepts of personal and collective identity as well as the role that a constitution may play in building the post-national constellation. It has been shown that Habermas has normative answers. Firstly, according to him, the fragile balance between the legal order and the particular cultures and traditions of a community has to be protected by the constitutional state. For that reason the political culture has to be “decoupled” from the majority culture. Secondly, the democratically structured attempt to achieve shared meaning has to find the delicate balance between the context-transcending universal normative claims and the claims of particular individual and collective life. Thirdly, it is possible to expand legally mediated civil solidarity trans-nationally, across Europe – we may recognize this development as the emergence of European identity –, since the process of democratic will-formation of citizens may get loose from the structures provided by the state if both shared democratic political cultures as well as a European-wide public sphere exist. The European Constitution may have a catalytic function in materialization of these conditions. It has been shown that in his deliberations Habermas tried to find a reflective equilibrium between the normative and the empirical.

  9. Nascent multicellular life and the emergence of individuality

    Indian Academy of Sciences (India)

    Silvia De Monte; Paul B Rainey

    2014-04-01

    The evolution of multicellular organisms from unicellular ancestors involves a shift in the level at which selection operates. It is usual to think about this shift in terms of the emergence of traits that cause heritable differences in reproductive output at the level of nascent collectives. Defining these traits and the causes of their origin lies at the heart of understanding the evolution of multicellular life. In working toward a mechanistic, take-nothing-for-granted account, we begin by recognizing that the standard Lewontin formulation of properties necessary and sufficient for evolution by natural selection does not necessarily encompass Darwinian evolution in primitive collectives where parent-offspring relationships may have been poorly defined. This, we suggest, limits the ability to conceptualize and capture the earliest manifestations of Darwinian properties. By way of solution we propose a relaxed interpretation of Lewontin’s conditions and present these in the form of a set of necessary requirements for evolution by natural selection based upon the establishment of genealogical connections between recurrences of collectives. With emphasis on genealogy – as opposed to reproduction – it is possible to conceive selection acting on collectives prior to any manifestation of heritable variance in fitness. Such possibility draws attention to the evolutionary emergence of traits that strengthen causal relationships between recurrences – traits likely to underpin the emergence of forms of multiplication that establish parent-offspring relationships. Application of this framework to collectives of marginal status, particularly those whose recurrence is not defined by genealogy, makes clear that change at the level of collectives need not arise from selection acting at the higher level. We conclude by outlining applicability of our framework to loosely defined collectives of cells, such as those comprising the slugs of social amoeba and microbes that

  10. Contesting a World-Constitution? Anti-Systemic Movements and Constitutional Forms in Ireland, 1848-2008

    Directory of Open Access Journals (Sweden)

    Thomas Murray

    2016-03-01

    Full Text Available Recent accounts of constitutional development have emphasised commonalities among diverse constitutions in terms of the transnational migration of legal institutions and ideas. World-systems analysis gives critical expression to this emergent intellectual trajectory. Since the late 18th century, successive, international waves of constitution-making have tended to correspond with decisive turning points in the contested formation of the historical capitalist world-system. The present article attempts to think through the nature of this correspondence in the Irish context. Changes to the Irish constitution, I suggest, owed to certain local manifestations of anti-systemic movements within the historical capitalist world-system and to constitution-makers’ attempts to contain – militarily, politically and ideologically – these movements’ democratic and egalitarian ideals and practices. Various configurations of the balance of power in Irish society between ‘national’ (core-peripheral and ‘social’ (capital-labour/‘other’ forces crystallised in constitutional form. Thus far, conservative and nationalist constitutional projects have tended to either dominate or incorporate social democratic and radical ones, albeit a process continually contested at critical junctures by civil society and by the organised left, both old and new.

  11. Studies in Historical Replication in Psychology VII: The Relative Utility of "Ancestor Analysis" from Scientific and Educational Vantages

    Science.gov (United States)

    Ranney, Michael Andrew

    2008-01-01

    This article discusses, from various vantages, Ryan Tweney's (this issue) pedagogical technique of employing historical replications of psychological experiments with graduate students in psychology. A "prima facie" perspective suggests great promise for this sort of academic "ancestor analysis," particularly given the enthusiasm and skill…

  12. Valuation In The Constitutional Era

    Directory of Open Access Journals (Sweden)

    Elmien du Plessis

    2015-12-01

    Full Text Available The Constitution brought about a new compensation regime for expropriations. Compensation for expropriation must now be "just and equitable". Whereas before the Constitution came into force market value played a central role in compensation for expropriation, market value is now only one factor or aspect of compensation that the court needs to take into account. Yet we find that courts tend to focus on market value and to still employ the valuation methods used to calculate market value. This article argues that the methods used to calculate the market value, once thought to be objective, are not as objective as was believed. While it is impossible to give judges specific tools for the assessment of market value, this article provides guidelines on how the calculation of compensation should be approached.

  13. Constitutive modeling for isotropic materials

    Science.gov (United States)

    Chan, K. S.; Lindholm, U. S.; Bodner, S. R.

    1988-01-01

    The third and fourth years of a 4-year research program, part of the NASA HOST Program, are described. The program goals were: (1) to develop and validate unified constitutive models for isotropic materials, and (2) to demonstrate their usefulness for structural analysis of hot section components of gas turbine engines. The unified models selected for development and evaluation were those of Bodner-Partom and of Walker. The unified approach for elastic-viscoplastic constitutive equations is a viable method for representing and predicting material response characteristics in the range where strain rate and temperature dependent inelastic deformations are experienced. This conclusion is reached by extensive comparison of model calculations against the experimental results of a test program of two high temperature Ni-base alloys, B1900+Hf and Mar-M247, over a wide temperature range for a variety of deformation and thermal histories including uniaxial, multiaxial, and thermomechanical loading paths. The applicability of the Bodner-Partom and the Walker models for structural applications has been demonstrated by implementing these models into the MARC finite element code and by performing a number of analyses including thermomechanical histories on components of hot sections of gas turbine engines and benchmark notch tensile specimens. The results of the 4-year program have been published in four annual reports. The results of the base program are summarized in this report. The tasks covered include: (1) development of material test procedures, (2) thermal history effects, and (3) verification of the constitutive model for an alternative material.

  14. An early modern human from Romania with a recent Neanderthal ancestor.

    Science.gov (United States)

    Fu, Qiaomei; Hajdinjak, Mateja; Moldovan, Oana Teodora; Constantin, Silviu; Mallick, Swapan; Skoglund, Pontus; Patterson, Nick; Rohland, Nadin; Lazaridis, Iosif; Nickel, Birgit; Viola, Bence; Prüfer, Kay; Meyer, Matthias; Kelso, Janet; Reich, David; Pääbo, Svante

    2015-08-13

    Neanderthals are thought to have disappeared in Europe approximately 39,000-41,000 years ago but they have contributed 1-3% of the DNA of present-day people in Eurasia. Here we analyse DNA from a 37,000-42,000-year-old modern human from Peştera cu Oase, Romania. Although the specimen contains small amounts of human DNA, we use an enrichment strategy to isolate sites that are informative about its relationship to Neanderthals and present-day humans. We find that on the order of 6-9% of the genome of the Oase individual is derived from Neanderthals, more than any other modern human sequenced to date. Three chromosomal segments of Neanderthal ancestry are over 50 centimorgans in size, indicating that this individual had a Neanderthal ancestor as recently as four to six generations back. However, the Oase individual does not share more alleles with later Europeans than with East Asians, suggesting that the Oase population did not contribute substantially to later humans in Europe.

  15. Hybrid apomicts trapped in the ecological niches of their sexual ancestors.

    Science.gov (United States)

    Mau, Martin; Lovell, John T; Corral, José M; Kiefer, Christiane; Koch, Marcus A; Aliyu, Olawale M; Sharbel, Timothy F

    2015-05-01

    Asexual reproduction is expected to reduce the adaptive potential to novel or changing environmental conditions, restricting or altering the ecological niche of asexual lineages. Asexual lineages of plants and animals are typically polyploid, an attribute that may influence their genetic variation, plasticity, adaptive potential, and niche breadth. The genus Boechera (Brassicaceae) represents an ideal model to test the relative ecological and biogeographic impacts of reproductive mode and ploidy because it is composed of diploid sexual and both diploid and polyploid asexual (i.e., apomictic) lineages. Here, we demonstrate a strong association between a transcriptionally conserved allele and apomictic seed formation. We then use this allele as a proxy apomixis marker in 1,649 accessions to demonstrate that apomixis is likely to be a common feature across the Boechera phylogeny. Phylogeographic analyses of these data demonstrate (i) species-specific niche differentiation in sexuals, (ii) extensive niche conservation between differing reproductive modes of the same species, (iii) ploidy-specific niche differentiation within and among species, and (iv) occasional niche drift between apomicts and their sexual ancestors. We conclude that ploidy is a substantially stronger and more common driver of niche divergence within and across Boechera species although variation in both traits may not necessarily lead to niche evolution on the species scale.

  16. Mechanism of photoprotection in the cyanobacterial ancestor of plant antenna proteins.

    Science.gov (United States)

    Staleva, Hristina; Komenda, Josef; Shukla, Mahendra K; Šlouf, Václav; Kaňa, Radek; Polívka, Tomáš; Sobotka, Roman

    2015-04-01

    Plants collect light for photosynthesis using light-harvesting complexes (LHCs)-an array of chlorophyll proteins that are able to reversibly switch from harvesting to energy-dissipation mode to prevent damage of the photosynthetic apparatus. LHC antennae as well as other members of the LHC superfamily evolved from cyanobacterial ancestors called high light-inducible proteins (Hlips). Here, we characterized a purified Hlip family member HliD isolated from the cyanobacterium Synechocystis sp. PCC 6803. We found that the HliD binds chlorophyll-a (Chl-a) and β-carotene and exhibits an energy-dissipative conformation. Using femtosecond spectroscopy, we demonstrated that the energy dissipation is achieved via direct energy transfer from a Chl-a Qy state to the β-carotene S1 state. We did not detect any cation of β-carotene that would accompany Chl-a quenching. These results provide proof of principle that this quenching mechanism operates in the LHC superfamily and also shed light on the photoprotective role of Hlips and the evolution of LHC antennae.

  17. Wild mallards have more "goose-like" bills than their ancestors: a case of anthropogenic influence?

    Directory of Open Access Journals (Sweden)

    Pär Söderquist

    Full Text Available Wild populations of the world's most common dabbling duck, the mallard (Anas platyrhynchos, run the risk of genetic introgression by farmed conspecifics released for hunting purposes. We tested whether bill morphology of free-living birds has changed since large-scale releases of farmed mallards started. Three groups of mallards from Sweden, Norway and Finland were compared: historical wild (before large-scale releases started, present-day wild, and present-day farmed. Higher density of bill lamellae was observed in historical wild mallards (only males. Farmed mallards had wider bills than present-day and historical wild ones. Present-day wild and farmed mallards also had higher and shorter bills than historical wild mallards. Present-day mallards thus tend to have more "goose-like" bills (wider, higher, and shorter than their ancestors. Our study suggests that surviving released mallards affect morphological traits in wild population by introgression. We discuss how such anthropogenic impact may lead to a maladapted and genetically compromised wild mallard population. Our study system has bearing on other taxa where large-scale releases of conspecifics with 'alien genes' may cause a cryptic invasive process that nevertheless has fitness consequences for individual birds.

  18. From offshore to onshore: multiple origins of shallow-water corals from deep-sea ancestors.

    Directory of Open Access Journals (Sweden)

    Alberto Lindner

    Full Text Available Shallow-water tropical reefs and the deep sea represent the two most diverse marine environments. Understanding the origin and diversification of this biodiversity is a major quest in ecology and evolution. The most prominent and well-supported explanation, articulated since the first explorations of the deep sea, holds that benthic marine fauna originated in shallow, onshore environments, and diversified into deeper waters. In contrast, evidence that groups of marine organisms originated in the deep sea is limited, and the possibility that deep-water taxa have contributed to the formation of shallow-water communities remains untested with phylogenetic methods. Here we show that stylasterid corals (Cnidaria: Hydrozoa: Stylasteridae--the second most diverse group of hard corals--originated and diversified extensively in the deep sea, and subsequently invaded shallow waters. Our phylogenetic results show that deep-water stylasterid corals have invaded the shallow-water tropics three times, with one additional invasion of the shallow-water temperate zone. Our results also show that anti-predatory innovations arose in the deep sea, but were not involved in the shallow-water invasions. These findings are the first robust evidence that an important group of tropical shallow-water marine animals evolved from deep-water ancestors.

  19. 29 CFR 452.18 - Constitutional officers.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Constitutional officers. 452.18 Section 452.18 Labor... DISCLOSURE ACT OF 1959 Coverage of Election Provisions § 452.18 Constitutional officers. A constitutional... identified as such or provided for in the constitution or other organic law of the labor organization. 17...

  20. Constitutive Effects of Performance Indicators

    DEFF Research Database (Denmark)

    Dahler-Larsen, Peter

    2014-01-01

    The idea that performance indicators in public management have unintended consequences is almost as old as performance measurement itself. But, is ‘unintended consequences’ an appropriate and insightful idea? The very term rests on an identification of intentions and assumptions about validity...... that are demonstrably problematic. Based on a distinction between trivial and advanced measure fixation, an argument is made for constitutive effects that are based on less problematic assumptions. Through this conceptual move, the political dimension of performance indicators is appreciated. The conceptual dimensions...

  1. Evolutionary origins of Hsp90 chaperones and a deep paralogy in their bacterial ancestors.

    Science.gov (United States)

    Stechmann, Alexandra; Cavalier-Smith, Thomas

    2004-01-01

    The 82-90 kD family of molecular chaperone proteins has homologs in eukaryotes (Hsp90) and many eubacteria (HtpG) but not in Archaebacteria. We used representatives of all four different eukaryotic paralogs (cytosolic, endoplasmic reticulum (ER), chloroplast, mitochondrial) together with numerous eubacterial HtpG proteins for phylogenetic analyses to investigate their evolutionary origins. Our trees confirm that none of the organellar Hsp90s derives from the endosymbionts of early eukaryotes. Contrary to previous suggestions of distant origins through lateral gene transfer (LGT) all eukaryote Hsp90s are related to Gram-positive eubacterial HtpG proteins. The nucleocytosolic, ER and chloroplast Hsp90 paralogs are clearly mutually related. The origin of mitochondrial Hsp90 is more obscure, as these sequences are deeply nested within eubacteria. Our trees also reveal a deep split within eubacteria into a group of mainly long-branching sequences (including the eukaryote mitochondrial Hsp90s) and another group comprising exclusively short-branching HtpG proteins, from which the cytosolic/ER versions probably arose. Both versions are present in several eubacterial phyla, suggesting gene duplication very early in eubacterial evolution and multiple independent losses thereafter. We identified one probable case of LGT within eubacteria. However, multiple losses can simply explain the evolutionary pattern of the eubacterial HtpG paralogs and predominate over LGT. We suggest that the actinobacterial ancestor of eukaryotes harbored genes for both eubacterial HtpG paralogs, as the actinobacterium Streptomyces coelicolor still does; one could have given rise to the mitochondrial Hsp90 and the other, following another duplication event in the ancestral eukaryote, to the cytosolic and ER Hsp90 homologs.

  2. Evidence of a chimeric genome in the cyanobacterial ancestor of plastids

    Directory of Open Access Journals (Sweden)

    Bhattacharya Debashish

    2008-04-01

    Full Text Available Abstract Background Horizontal gene transfer (HGT is a vexing fact of life for microbial phylogeneticists. Given the substantial rates of HGT observed in modern-day bacterial chromosomes, it is envisaged that ancient prokaryotic genomes must have been similarly chimeric. But where can one find an ancient prokaryotic genome that has maintained its ancestral condition to address this issue? An excellent candidate is the cyanobacterial endosymbiont that was harnessed over a billion years ago by a heterotrophic protist, giving rise to the plastid. Genetic remnants of the endosymbiont are still preserved in plastids as a highly reduced chromosome encoding 54 – 264 genes. These data provide an ideal target to assess genome chimericism in an ancient cyanobacterial lineage. Results Here we demonstrate that the origin of the plastid-encoded gene cluster for menaquinone/phylloquinone biosynthesis in the extremophilic red algae Cyanidiales contradicts a cyanobacterial genealogy. These genes are relics of an ancestral cluster related to homologs in Chlorobi/Gammaproteobacteria that we hypothesize was established by HGT in the progenitor of plastids, thus providing a 'footprint' of genome chimericism in ancient cyanobacteria. In addition to menB, four components of the original gene cluster (menF, menD, menC, and menH are now encoded in the nuclear genome of the majority of non-Cyanidiales algae and plants as the unique tetra-gene fusion named PHYLLO. These genes are monophyletic in Plantae and chromalveolates, indicating that loci introduced by HGT into the ancestral cyanobacterium were moved over time into the host nucleus. Conclusion Our study provides unambiguous evidence for the existence of genome chimericism in ancient cyanobacteria. In addition we show genes that originated via HGT in the cyanobacterial ancestor of the plastid made their way to the host nucleus via endosymbiotic gene transfer (EGT.

  3. Specimen-level phylogenetics in paleontology using the Fossilized Birth-Death model with sampled ancestors.

    Science.gov (United States)

    Cau, Andrea

    2017-01-01

    Bayesian phylogenetic methods integrating simultaneously morphological and stratigraphic information have been applied increasingly among paleontologists. Most of these studies have used Bayesian methods as an alternative to the widely-used parsimony analysis, to infer macroevolutionary patterns and relationships among species-level or higher taxa. Among recently introduced Bayesian methodologies, the Fossilized Birth-Death (FBD) model allows incorporation of hypotheses on ancestor-descendant relationships in phylogenetic analyses including fossil taxa. Here, the FBD model is used to infer the relationships among an ingroup formed exclusively by fossil individuals, i.e., dipnoan tooth plates from four localities in the Ain el Guettar Formation of Tunisia. Previous analyses of this sample compared the results of phylogenetic analysis using parsimony with stratigraphic methods, inferred a high diversity (five or more genera) in the Ain el Guettar Formation, and interpreted it as an artifact inflated by depositional factors. In the analysis performed here, the uncertainty on the chronostratigraphic relationships among the specimens was included among the prior settings. The results of the analysis confirm the referral of most of the specimens to the taxa Asiatoceratodus, Equinoxiodus, Lavocatodus and Neoceratodus, but reject those to Ceratodus and Ferganoceratodus. The resulting phylogeny constrained the evolution of the Tunisian sample exclusively in the Early Cretaceous, contrasting with the previous scenario inferred by the stratigraphically-calibrated topology resulting from parsimony analysis. The phylogenetic framework also suggests that (1) the sampled localities are laterally equivalent, (2) but three localities are restricted to the youngest part of the section; both results are in agreement with previous stratigraphic analyses of these localities. The FBD model of specimen-level units provides a novel tool for phylogenetic inference among fossils but also

  4. Scapular shape of extant hominoids and the African ape/modern human last common ancestor.

    Science.gov (United States)

    Green, David J; Spiewak, Ted A; Seitelman, Brielle; Gunz, Philipp

    2016-05-01

    Newly discovered early hominin fossil scapulae have bolstered investigations of scapular shape, which have long been used to interpret behavioral variation among primates. However, unexpected similarities between Pongo and Homo - particularly in scapular spine orientation - have raised questions about the functional utility of scapular morphology and its phylogenetic context in the hominin lineage. Not surprisingly, significant disagreement surrounds disparate morphological reconstructions of the modern human/African ape last common ancestor (LCA). Our study utilizes geometric morphometric (GM) approaches - two employing homologous, anatomical landmarks and a "spine-free" alternative using 98 sliding semilandmarks along the boundary of the subscapular fossa. The landmark-based "wireframe" GM analysis principally sorted groups by spine orientation: Homo and Pongo were similar to one another with more transversely-oriented spines as compared to Hylobates and the African apes. In contrast, Homo and Gorilla clustered together in our semilandmark analysis with superoinferiorly broad blades. Pan scapulae were similar, but had more mediolaterally compressed blades and laterally-positioned superior angles. Hylobates was superoinferiorly narrow, yet obliquely expanded relative to the vertebral border. Pongo scapulae were unique among hominoids in being nearly as broad as they were long. Previously documented 'convergence' of Homo and Pongo scapulae appears to be principally driven by similarities in spine orientation, rather than overall blade shape. Therefore, we contend that it is more parsimonious to reconstruct the African ape/Homo LCA scapula as being Gorilla-like, especially in light of similar characterizations of certain fossil hominin scapulae. Accordingly, the evolution of Pan (highly oblique spine and laterally-situated superior angle) and Homo (transversely-oriented spine) scapular morphology would have involved relatively minor shifts from this ancestral

  5. Sequence Divergence of Microsatellites and Phylogeny Analysis in Tetraploid Cotton Species and Their Putative Diploid Ancestors

    Institute of Scientific and Technical Information of China (English)

    Wang-Zhen GUO; Dong FANG; Wen-Duo YU; Tian-Zhen ZHANG

    2005-01-01

    To determine the level of microsatellite sequence differences and to use the information to construct a phylogenetic relationship for cultivated tetraploid cotton (Gossypium spp.) species and their putative diploid ancestors, 10 genome-derived microsatellite primer pairs were used to amplify eight species,including two tetraploid and six diploid species, in Gossypium. A total of 92 unique amplicons were resolved using polyacrylamide gel electrophoresis. Each amplicon was cloned, sequenced, and analyzed using standard phylogenetic software. Allelic diversities were caused mostly by changes in the number of simple sequence repeat (SSR) motif repeats and only a small proportion resulted from interruption of the SSR motif within the locus for the same genome. The frequency of base substitutions was 0.5%-1.0% in different genomes, with only few indels found. Based on the combined 10 SSR flanking sequence data, the homology of A-genome diploid species averaged 98.9%, even though most of the amplicons were of the same size, and the sequence homology between G. gossypioides (Ulbr.) Standl. and three other D-genome species (G.raimondii Ulbr., G. davidsonii Kell., and G. thurberi Tod.) was 98.5%, 98.6%, and 98.5%, respectively.Phylogenetic trees of the two allotetraploid species and their putative diploid progenitors showed that homoelogous sequences from the A- and D-subgenome were still present in the polyploid subgenomes and they evolved independently. Meanwhile, homoelogous sequence interaction that duplicated loci in the polyploid subgenomes became phylogenetic sisters was also found in the evolutionary history of tetraploid cotton species. The results of the present study suggest that evaluation of SSR variation at the sequence level can be effective in exploring the evolutionary relationships among Gossypuim species.

  6. The Dilemma of Constitutional Comparativism

    NARCIS (Netherlands)

    C.M. Zoethout

    2011-01-01

    Over the past decade, a trend of referring to foreign law and foreign judicial decisions has emerged in the case-law of both the American Supreme Court and the European Court of Human Rights. Two of the most controversial cases of the Supreme Court in this era were partly based on non-US law. The Eu

  7. 75 FR 57835 - Constitution Day and Citizenship Day, Constitution Week, 2010

    Science.gov (United States)

    2010-09-22

    ... Proclamation 8562--Constitution Day and Citizenship Day, Constitution Week, 2010 Proclamation 8563--National... President ] Proclamation 8562 of September 16, 2010 Constitution Day and Citizenship Day, Constitution Week... Convention in Philadelphia established a Constitution for the United States of America, signing the...

  8. Constitutive model for overconsolidated clays

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Based on the relationships between the Hvorslev envelope,the current yield sur-face and the reference yield surface,a new constitutive model for overconsolidated clays is proposed. It adopts the unified hardening parameter,to which the potential failure stress ratio and the characteristic state stress ratio are introduced. The model can describe many characteristics of overconsolidated clays,including stress-strain relationships,strain hardening and softening,stress dilatancy,and stress path dependency. Compared with the Cam-clay model,the model only re-quires one additional soil parameter which is the slope of the Hvorslev envelope. Comparisons with data from triaxial drained compression tests for Fujinomori clay show that the proposed model can rationally describe overconsolidated properties. In addition,the model is also used to predict the stress-strain relationship in the isotropic consolidation condition and the stress paths in the undrained triaxial compression tests.

  9. An Evolutionary Network of Genes Present in the Eukaryote Common Ancestor Polls Genomes on Eukaryotic and Mitochondrial Origin

    OpenAIRE

    Thiergart, T.; Landan, G; Schenk, M.; Dagan, T.; Martin, W F

    2012-01-01

    To test the predictions of competing and mutually exclusive hypotheses for the origin of eukaryotes, we identified from a sample of 27 sequenced eukaryotic and 994 sequenced prokaryotic genomes 571 genes that were present in the eukaryote common ancestor and that have homologues among eubacterial and archaebacterial genomes. Maximum-likelihood trees identified the prokaryotic genomes that most frequently contained genes branching as the sister to the eukaryotic nuclear homologues. Among the a...

  10. Diabetic Emergencies

    Science.gov (United States)

    ... Emergencies A-Z Share this! Home » Emergency 101 Diabetic Emergencies It is estimated that more than 20 ... they have it. The best way to prevent diabetic emergencies is to effectively manage the disease through ...

  11. Childhood Emergencies

    Science.gov (United States)

    ... emergency physicians. They receive comprehensive training in treating childhood emergencies and have more training in pediatric emergencies than other physicians, including pediatricians. Does Your Child's School Know About Food Allergies? - 8/10/2015 The nation's emergency physician ...

  12. Constitutional Analysis of Educational Vouchers in Minnesota.

    Science.gov (United States)

    Bruno, Robert J.

    1989-01-01

    Voucher plans that involve payments of tax funds to private schools are suspect on both constitutional and public policy grounds. Analyzes the constitutional issues raised by a recent attempt at voucher legislation in Minnesota. (MLF)

  13. The communicative constitution of representation and exclusion

    NARCIS (Netherlands)

    Wessel, van M.G.J.

    2014-01-01

    In the light of current debate on representation, specifically engaging with literature showing how representation is communicatively constituted, this paper empirically shows how exclusion also can be seen as communicatively constituted. The interpretive approach toward communication employed in th

  14. Theoretical Issues of the Constitutional Regulation Mechanism

    Science.gov (United States)

    Zhussupova, Guldaray B.; Zhailyaubayev, Rassul T.; Ukin, Symbat K.; Shunayeva, Sylu M.; Nurmagambetov, Rachit G.

    2016-01-01

    The purpose of this research is to define the concept of "constitutional regulation mechanism." The definition of the concept of "constitutional regulation mechanism" will give jurists and legislators a theoretical framework for developing legal sciences, such as the constitutional law and the theory of state and law. The…

  15. The Constitution of the Republic of Estonia

    Index Scriptorium Estoniae

    2005-01-01

    Raamat sisaldab ka: The Constitution of the Republic of Estonia amendment act ; The Constitution of the Republic of Estonia implementation act ; Act to amend the Constitution of the Republic of Estonia for election of local government councils for term of four years

  16. The Constitution of the Republic of Estonia

    Index Scriptorium Estoniae

    2009-01-01

    Sisaldab ka: The Constitution of the Republic of Estonia Amendment Act. The Constitution of the Republic of Estonia Implementation Act. Act to Amend the Constitution of the Republic of Estonia for Election of Local Government Councils for Term of Four Years

  17. 7 CFR 718.201 - Farm constitution.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Farm constitution. 718.201 Section 718.201 Agriculture... Reconstitution of Farms, Allotments, Quotas, and Bases § 718.201 Farm constitution. (a) In order to implement... this section. The constitution and identification of land as a farm for the first time and...

  18. Multigene eukaryote phylogeny reveals the likely protozoan ancestors of opisthokonts (animals, fungi, choanozoans) and Amoebozoa.

    Science.gov (United States)

    Cavalier-Smith, Thomas; Chao, Ema E; Snell, Elizabeth A; Berney, Cédric; Fiore-Donno, Anna Maria; Lewis, Rhodri

    2014-12-01

    Animals and fungi independently evolved from the protozoan phylum Choanozoa, these three groups constituting a major branch of the eukaryotic evolutionary tree known as opisthokonts. Opisthokonts and the protozoan phylum Amoebozoa (amoebae plus slime moulds) were previously argued to have evolved independently from the little-studied, largely flagellate, protozoan phylum, Sulcozoa. Sulcozoa are a likely evolutionary link between opisthokonts and the more primitive excavate flagellates that have ventral feeding grooves and the most primitive known mitochondria. To extend earlier sparse evidence for the ancestral (paraphyletic) nature of Sulcozoa, we sequenced transcriptomes from six gliding flagellates (two apusomonads; three planomonads; Mantamonas). Phylogenetic analyses of 173-192 genes and 73-122 eukaryote-wide taxa show Sulcozoa as deeply paraphyletic, confirming that opisthokonts and Amoebozoa independently evolved from sulcozoans by losing their ancestral ventral groove and dorsal pellicle: Apusozoa (apusomonads plus anaerobic breviate amoebae) are robustly sisters to opisthokonts and probably paraphyletic, breviates diverging before apusomonads; Varisulca (planomonads, Mantamonas, and non-gliding flagellate Collodictyon) are sisters to opisthokonts plus Apusozoa and Amoebozoa, and possibly holophyletic; Glissodiscea (planomonads, Mantamonas) may be holophyletic, but Mantamonas sometimes groups with Collodictyon instead. Taxon and gene sampling slightly affects tree topology; for the closest branches in Sulcozoa and opisthokonts, proportionally reducing missing data eliminates conflicts between homogeneous-model maximum-likelihood trees and evolutionarily more realistic site-heterogeneous trees. Sulcozoa, opisthokonts, and Amoebozoa constitute an often-pseudopodial 'podiate' clade, one of only three eukaryotic 'supergroups'. Our trees indicate that evolution of sulcozoan dorsal pellicle, ventral pseudopodia, and ciliary gliding (probably simultaneously

  19. 78 FR 39721 - Constitution Pipeline Company, LLC; Notice of Application

    Science.gov (United States)

    2013-07-02

    ... Energy Regulatory Commission Constitution Pipeline Company, LLC; Notice of Application Take notice that on June 13, 2013, Constitution Pipeline Company, LLC (Constitution), having its principal place of...\\ Constitution further requests that the Commission grant Constitution a blanket certificate...

  20. State Constitutionalism: Completing the Interdisciplinary Study of Constitutional Law and Political Theory.

    Science.gov (United States)

    Williams, Robert F.

    1993-01-01

    Argues that a complete and accurate understanding of constitutional history and constitutional law requires the study of state constitutions. Maintains that state constitutions contain a coherent political theory that is, in important respects, at variance with the concept of federalism. (CFR)

  1. 77 FR 57981 - Constitution Day and Citizenship Day, Constitution Week, 2012

    Science.gov (United States)

    2012-09-18

    ... September 18, 2012 Part VI The President Proclamation 8862--Constitution Day and Citizenship Day, Constitution Week, 2012 #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 77 , No. 181... ] Proclamation 8862 of September 13, 2012 Constitution Day and Citizenship Day, Constitution Week, 2012 By...

  2. 3 CFR 8418 - Proclamation 8418 of September 16, 2009. Constitution Day and Citizenship Day, Constitution Week...

    Science.gov (United States)

    2010-01-01

    .... Constitution Day and Citizenship Day, Constitution Week, 2009 8418 Proclamation 8418 Presidential Documents Proclamations Proclamation 8418 of September 16, 2009 Proc. 8418 Constitution Day and Citizenship Day, Constitution Week, 2009By the President of the United States of America A Proclamation The United...

  3. 78 FR 57777 - Constitution Day and Citizenship Day, Constitution Week, 2013

    Science.gov (United States)

    2013-09-19

    ... September 19, 2013 Part IV The President Proclamation 9019--Constitution Day and Citizenship Day, Constitution Week, 2013 Proclamation 9020--Honoring the Victims of the Tragedy at the Washington Navy Yard #0... September 16, 2013 Constitution Day and Citizenship Day, Constitution Week, 2013 By the President of...

  4. Ancestors We Didn’t Even Know We Had”: Alice Walker, Asian Religion, and Ethnic Authenticity

    Directory of Open Access Journals (Sweden)

    Kyle Garton-Gundling

    2015-03-01

    Full Text Available Recent debates about the ethics of identity in a global age have dealt with how to prioritize conflicting local and global allegiances. Guided by these concerns, the fiction of Alice Walker develops a distinctive view of how local cultures and global movements can fruitfully interact. This vision depends on concepts from Asian religions, a major influence that critics of Walker have largely overlooked. Walker promotes Hindu and Buddhist meditation in a context of widespread African American skepticism toward Asian religions. According to widespread notions of cultural authenticity, Asian religions cannot nourish an African American connection to ethnic roots. In response to this challenge, Alice Walker’s fiction portrays Hindu and Buddhist mystics as African Americans’ ancestors, thus positioning these faiths as authentically black. By creatively enfolding Asian religions into her sense of African American heritage, Walker builds a spiritual cosmopolitanism that relies on claims of ancestral affiliation even when these claims are not literal. This strategy is Walker’s effort to create a new paradigm of cultural authenticity, one that allows individuals and groups to choose their ancestors. Walker’s approach seeks to incorporate disparate global influences while still valorizing the figure of the ancestor. This innovative approach places Walker at the forefront of a growing number of African American artists and intellectuals who promote Asian religions to American minorities. Walker’s work vividly dramatizes larger concerns in transnational American Studies: Eastern philosophy’s relevance to identity politics, the tensions between universal ideals and cultural specifics, and the ethics of cross-cultural appropriation.

  5. An evolutionary network of genes present in the eukaryote common ancestor polls genomes on eukaryotic and mitochondrial origin.

    Science.gov (United States)

    Thiergart, Thorsten; Landan, Giddy; Schenk, Marc; Dagan, Tal; Martin, William F

    2012-01-01

    To test the predictions of competing and mutually exclusive hypotheses for the origin of eukaryotes, we identified from a sample of 27 sequenced eukaryotic and 994 sequenced prokaryotic genomes 571 genes that were present in the eukaryote common ancestor and that have homologues among eubacterial and archaebacterial genomes. Maximum-likelihood trees identified the prokaryotic genomes that most frequently contained genes branching as the sister to the eukaryotic nuclear homologues. Among the archaebacteria, euryarchaeote genomes most frequently harbored the sister to the eukaryotic nuclear gene, whereas among eubacteria, the α-proteobacteria were most frequently represented within the sister group. Only 3 genes out of 571 gave a 3-domain tree. Homologues from α-proteobacterial genomes that branched as the sister to nuclear genes were found more frequently in genomes of facultatively anaerobic members of the rhiozobiales and rhodospirilliales than in obligate intracellular ricketttsial parasites. Following α-proteobacteria, the most frequent eubacterial sister lineages were γ-proteobacteria, δ-proteobacteria, and firmicutes, which were also the prokaryote genomes least frequently found as monophyletic groups in our trees. Although all 22 higher prokaryotic taxa sampled (crenarchaeotes, γ-proteobacteria, spirochaetes, chlamydias, etc.) harbor genes that branch as the sister to homologues present in the eukaryotic common ancestor, that is not evidence of 22 different prokaryotic cells participating at eukaryote origins because prokaryotic "lineages" have laterally acquired genes for more than 1.5 billion years since eukaryote origins. The data underscore the archaebacterial (host) nature of the eukaryotic informational genes and the eubacterial (mitochondrial) nature of eukaryotic energy metabolism. The network linking genes of the eukaryote ancestor to contemporary homologues distributed across prokaryotic genomes elucidates eukaryote gene origins in a dialect

  6. Entrepreneurship, Emerging Technologies, Emerging Markets

    NARCIS (Netherlands)

    Thukral, Inderpreet S.; Von Ehr, James; Groen, Aard J.; Sijde, van der Peter; Adham, Khairul Akmaliah

    2008-01-01

    Academics and practitioners alike have long understood the benefits, if not the risks, of both emerging markets and emerging technologies.Yet it is only recently that foresighted firms have embraced emerging technologies and emerging markets through entrepreneurial activity. Emerging technologies an

  7. Constitutive receptor systems for drug discovery.

    Science.gov (United States)

    Chen, G; Jayawickreme, C; Way, J; Armour, S; Queen, K; Watson, C; Ignar, D; Chen, W J; Kenakin, T

    1999-12-01

    This paper discusses the use of constitutively active G-protein-coupled receptor systems for drug discovery. Specifically, the ternary complex model is used to define the two major theoretical advantages of constitutive receptor screening-namely, the ability to detect antagonists as well as agonists directly and the fact that constitutive systems are more sensitive to agonists. In experimental studies, transient transfection of Chinese hamster ovary cyclic AMP response element (CRE) luciferase reporter cells with cDNA for human parathyroid hormone receptor, glucagon receptor, and glucagon-like peptide (GLP-1) receptor showed cDNA concentration-dependent constitutive activity with parathyroid hormone (PTH-1) and glucagon. In contrast, no constitutive activity was observed for GLP-1 receptor, yet responses to GLP-1 indicated that receptor expression had taken place. In another functional system, Xenopus laevi melanophores transfected with cDNA for human calcitonin receptor showed constitutive activity. Nine ligands for the calcitonin receptor either increased or decreased constitutive activity in this assay. The sensitivity of the system to human calcitonin increased with increasing constitutive activity. These data indicate that, for those receptors which naturally produce constitutive activity, screening in this mode could be advantageous over other methods.

  8. Statistical Constitutive Equation of Aramid Fiber Bundles

    Institute of Scientific and Technical Information of China (English)

    熊杰; 顾伯洪; 王善元

    2003-01-01

    Tensile impact tests of aramid (Twaron) fiber bundles were carried om under high strain rates with a wide range of 0. 01/s~1000/s by using MTS and bar-bar tensile impact apparatus. Based on the statistical constitutive model of fiber bundles, statistical constitutive equations of aramid fiber bundles are derived from statistical analysis of test data at different strain rates. Comparison between the theoretical predictions and experimental data indicates statistical constitutive equations fit well with the experimental data, and statistical constitutive equations of fiber bundles at different strain rates are valid.

  9. The earliest-known ancestors of Recent Priapulomorpha from the Early Cambrian Chengjiang Lagerst(``a)tte

    Institute of Scientific and Technical Information of China (English)

    HAN Jian; SHU Degan; ZHANG Zhifei; LIU Jianni

    2004-01-01

    The taxonomy of an early ancestor of Recent Priapulidae, Xiaoheiqingella peculiaris (= Yunnanpriapulus halteroformis Huang et al., 2004) from the Early Cambrian Chengjiang fossil LagerstStte, is revised. Morphological characters comprise a pair of caudal appendages rather than a single appendage flanking the trunk end and a possible urogenital duct found inside the preanal region. An additional extremely rare fossil priapulid worm, Paratubiluchus bicaudatus gen. nov., sp. nov. is also described herein. Its diagnostic characters are: an introvert bearing 25 longitudinal rows of scalids, a distinct neck region, no annulus on the oval trunk, and a pair of caudal appendages. The proportion of body parts is similar in size to that of loricate larvae of Recent priapulids and larva-formed Palaeopriapulitidae. Taking account of the features of Xiaoheiqingella, bicaudal appendages are considered to be a synapomorphy of Priapulidae and Tubiluchidae. Paratubiluchus gen. nov. is most likely a candidate for the ancestor of the Tubiluchidae; it probably originated from a larva-formed priapulid with 25 rows of scalids, thus representing an intermediate link between the priapulids in mature-form and the priapulids with Iorica.

  10. Ancient wolf genome reveals an early divergence of domestic dog ancestors and admixture into high-latitude breeds.

    Science.gov (United States)

    Skoglund, Pontus; Ersmark, Erik; Palkopoulou, Eleftheria; Dalén, Love

    2015-06-01

    The origin of domestic dogs is poorly understood [1-15], with suggested evidence of dog-like features in fossils that predate the Last Glacial Maximum [6, 9, 10, 14, 16] conflicting with genetic estimates of a more recent divergence between dogs and worldwide wolf populations [13, 15, 17-19]. Here, we present a draft genome sequence from a 35,000-year-old wolf from the Taimyr Peninsula in northern Siberia. We find that this individual belonged to a population that diverged from the common ancestor of present-day wolves and dogs very close in time to the appearance of the domestic dog lineage. We use the directly dated ancient wolf genome to recalibrate the molecular timescale of wolves and dogs and find that the mutation rate is substantially slower than assumed by most previous studies, suggesting that the ancestors of dogs were separated from present-day wolves before the Last Glacial Maximum. We also find evidence of introgression from the archaic Taimyr wolf lineage into present-day dog breeds from northeast Siberia and Greenland, contributing between 1.4% and 27.3% of their ancestry. This demonstrates that the ancestry of present-day dogs is derived from multiple regional wolf populations.

  11. The New Role of the Constitutive Rule

    NARCIS (Netherlands)

    Hindriks, Frank

    2003-01-01

    Searle used to analyze institutional facts in terms of the constitutive rule. In his more elaborate account in The Construction of Social Reality he introduces the notion of a status function. The “counts as” locution is central to both the constitutive rule and the status function. The main questio

  12. Culture (and religion in constitutional adjudication

    Directory of Open Access Journals (Sweden)

    C Rautenbach

    2003-10-01

    Full Text Available The faculty of law of the Potchefstroom University for Christian Higher Education in corroboration with the Konrad-Adenauer-Stifttung embarked on a study on Politics, Socio-Economic Issues and Culture in Constitutional Adjudication. The aim of the project is twofold. The first aim is to analyse the influence of political, socio-economic and cultural considerations on the constitutional court’s interpretation and application of the Bill of Rights. The second aim is to develop practical guidelines (based on the findings during the analysing process for South African courts confronted with issues of a political, socio-economic and cultural nature. This article is concerned with initiating discussions of the decisions of the constitutional court with regard to cultural and religious rights.Before we can explore the role of political, socio-economic and cultural (and religious rights in the decisions of the constitutional court it is important to discuss a few preliminary issues. In this article the meaning of culture and religion within the South African context receives some attention. Secondly, some preliminary comments regarding constitutional protection of culturally and religiously based rights will be made.We are well aware that this is a daunting task, not only in view of the seemingly abysmal gap between the applicable constitutional rights and values enshrined in the 1996 Constitution that, in some instances over centuries, brought about customs and practices within “traditional” communities which, seemingly, infringe on certain constitutional values and rights.

  13. A Federal Constitution for the European Union

    DEFF Research Database (Denmark)

    Sweeney, Richard J.

    2003-01-01

    A constitution is more likely to be accepted if it federalizes those issues that arewidely seen as needing complete harmonization. A constitution is more likely to endure if thefederal government does not have powers that are not vital to it but which may alienate somemember states to the point...

  14. Subsidiarity under the Constitution for Europe

    NARCIS (Netherlands)

    F.A.N.J. Goudappel (Flora)

    2006-01-01

    textabstractThe principle of subsidiarity lies at the heart of the European Union’s strife to bring the EU closer to the citizen. Yet, it appears to be failing to do so in its present form. Therefore, the new Treaty Establishing a Constitution for Europe [hereafter: European Constitution] has the i

  15. Financial markets and the current account: emerging Europe versus emerging Asia

    OpenAIRE

    Herrmann, Sabine; Winkler, Adalbert

    2009-01-01

    Financial globalisation has been associated with divergent current account patterns in emerging market economies. While countries in emerging Asia have been running sizeable current account surpluses, countries in emerging Europe have been facing large current account deficits. In this paper we test for the relevance of financial market characteristics in explaining divergent current account patterns in emerging Europe and emerging Asia based on the assumption that both regions constitute two...

  16. [Oil and Hazardous Substance Spill Response Emergencies

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — A major oil or hazardous substance spill may constitute an emergency situation requiring prompt actions by the Service to protect threatened natural resources. This...

  17. Constitutional dynamic chemistry: bridge from supramolecular chemistry to adaptive chemistry.

    Science.gov (United States)

    Lehn, Jean-Marie

    2012-01-01

    Supramolecular chemistry aims at implementing highly complex chemical systems from molecular components held together by non-covalent intermolecular forces and effecting molecular recognition, catalysis and transport processes. A further step consists in the investigation of chemical systems undergoing self-organization, i.e. systems capable of spontaneously generating well-defined functional supramolecular architectures by self-assembly from their components, thus behaving as programmed chemical systems. Supramolecular chemistry is intrinsically a dynamic chemistry in view of the lability of the interactions connecting the molecular components of a supramolecular entity and the resulting ability of supramolecular species to exchange their constituents. The same holds for molecular chemistry when the molecular entity contains covalent bonds that may form and break reversibility, so as to allow a continuous change in constitution by reorganization and exchange of building blocks. These features define a Constitutional Dynamic Chemistry (CDC) on both the molecular and supramolecular levels.CDC introduces a paradigm shift with respect to constitutionally static chemistry. The latter relies on design for the generation of a target entity, whereas CDC takes advantage of dynamic diversity to allow variation and selection. The implementation of selection in chemistry introduces a fundamental change in outlook. Whereas self-organization by design strives to achieve full control over the output molecular or supramolecular entity by explicit programming, self-organization with selection operates on dynamic constitutional diversity in response to either internal or external factors to achieve adaptation.The merging of the features: -information and programmability, -dynamics and reversibility, -constitution and structural diversity, points to the emergence of adaptive and evolutive chemistry, towards a chemistry of complex matter.

  18. Emergence of life: from functional RNA selection to natural selection and beyond.

    Science.gov (United States)

    Wong, Jeffrey Tze-Fei

    2014-06-01

    This study tracks the rise, evolution and post-evolution of the genetic information system through emergence of life. The major stages traversed include prebiotic synthesis, functional RNA selection by metabolite, RNA World, peptidated RNA world, co-evolution of genetic code and amino acid biosynthesis, last universal common ancestor, Darwinian evolution and synthetic life.

  19. CONSTITUTIONAL TRADITIONALISM IN THE ROBERTS COURT

    Directory of Open Access Journals (Sweden)

    Louis J Virelli III

    2011-05-01

    Full Text Available The debate over the role of traditionalism in constitutional interpretation has itself become a tradition. It remains a popular and controversial topic among constitutional scholars and presents normative questions that are as divisive, difficult, and important today as at the Founding. Missing from the discussion, however, is a comprehensive account of how the Supreme Court has employed traditionalism-an approach that looks for meaning in present manifestations of longstanding practices or beliefs-in its constitutional jurisprudence. This project is the first to fill this gap by providing an exhaustive and systematic analysis of the Court's use of constitutional traditionalism. This article focuses on the Roberts Court's first five terms to provide an empirical foundation that will not only offer previously unavailable insights into the Court's current traditionalist practices, but will also set forth a useful framework for the ongoing normative debate over traditionalism. This project uses content analysis of key terms to identify every instance in which the Roberts Court employed traditionalism to interpret the Constitution. More specifically, this project set out to answer the following three questions: First, how frequently does the Roberts Court employ traditionalism in its constitutional jurisprudence? Second, how robust is the Court's use of traditionalism (i.e., is it used to interpret a broad or narrow range of constitutional provisions? And finally, how often and in what contexts do individual Justices on the Roberts Court rely on traditionalism in their own constitutional opinions? The research provided here suggests answers to all three of these questions. First, the data indicate that traditionalism has been relied upon regularly by the Roberts Court, appearing in nearly half of the Court's constitutional cases. Second, traditionalism is frequently applied to a wide variety of constitutional provisions: Two-thirds of the

  20. Habermas and viroli on constitution and patria: a defense of constitutional patriotism

    OpenAIRE

    2012-01-01

    This study aims to explore Viroli‟s republican patriotism and Habermas‟s constitutional patriotism by starting off from the fundamental question what makes constitutional patriotism different from republican patriotism. The main motivation of such an examination comes from Viroli‟s argument that Habermas‟s constitutional patriotism is a version of republican patriotism. Against Viroli‟s claim, the main argument of this thesis is that Habermas‟s theory of constitutional patriotism cannot be in...

  1. Closing in on the constitution of consciousness

    Directory of Open Access Journals (Sweden)

    Steven M. Miller

    2014-11-01

    Full Text Available The science of consciousness is a nascent and thriving field of research that is founded on identifying the minimally sufficient neural correlates of consciousness. However, I have argued that it is the neural constitution of consciousness that science seeks to understand and that there are no evident strategies for distinguishing the correlates and constitution of (phenomenal consciousness. Here I review this correlation/constitution distinction problem and challenge the existing foundations of consciousness science. I present the main analyses from a longer paper in press on this issue, focusing on recording, inhibition, stimulation and combined inhibition/stimulation strategies, including proposal of the Jenga analogy to illustrate why identifying the minimally sufficient neural correlates of consciousness should not be considered the ultimate target of consciousness science. Thereafter I suggest that while combined inhibition and stimulation strategies might identify some constitutive neural activities — indeed minimally sufficient constitutive neural activities — such strategies fail to identify the whole neural constitution of consciousness and thus the correlation/constitution distinction problem is not fully solved. Various clarifications, potential objections and related scientific and philosophical issues are also discussed and I conclude by proposing new foundational claims for consciousness science.

  2. 76 FR 58705 - Constitution Day and Citizenship Day, Constitution Week, 2011

    Science.gov (United States)

    2011-09-21

    ... September 21, 2011 Part V The President Proclamation 8714--Constitution Day and Citizenship Day, Constitution Week, 2011 Proclamation 8715--National Employer Support of the Guard and Reserve Week, 2011...;The President ] Proclamation 8714 of September 16, 2011 Constitution Day and Citizenship...

  3. Configuring a constitutional state: Officials and assemblymen at the 1909 Sichuan provincial assembly meeting

    OpenAIRE

    2013-01-01

    This article examines two potential configurations of the constitutional state at the time of Constitutional Reform. One was from Sichuan Governor-General Zhao Erxun, who claimed that "all political power belongs to the state." The other was from the Sichuan assemblymen, who were inarticulate at first, but, when the meeting closed one and a half months later, firmly announced that "there would be no taxation without supervision." Both views emerged during the 1909 Provincial Assembly meeting ...

  4. Economic Consequences of the New Iraqi Constitution

    OpenAIRE

    Looney, Robert E.

    2006-01-01

    Gulf Yearbook 2005-2006, Gulf Research Center, 2006, pp.365-382. Constitutions can play a critical role in founding and unifying new or renewing states: Iraq is no exception. A new constitution for post-Saddam Iraq can play a key role in reunifying and strengthening the national consciousness of the country. It can also lay the foundation for the creation of a viable dynamic economy. To many the constitution drafted and ratified in the summer of 2005 holds out this promise. To ...

  5. [The right to health. Constitutional dimensions].

    Science.gov (United States)

    Pestalozza, C

    2007-09-01

    A fundamental "right to health" is expressly guaranteed by the constitutions of several Bundesländer, but unknown to the German Federal Constitution. Instead the Federal Constitutional Court has - especially on the basis of related human rights - developed the obligation of the State to protect everybody's life and physical integrity, which in some respects comes near to a "right to health". The State's autonomy in financial matters, the scarcity of its financial resources and the individual's natural responsibility for his own health though advise against exaggerated hopes set in a "right to health".

  6. Constitutional and Anatomical Characteristics of Mature Women

    Institute of Scientific and Technical Information of China (English)

    Vladimir NNikolenko; DmitryBNikityuk; SvetlanaVKlochkova; AnastasiaABahmet

    2015-01-01

    Objective To identify the constitutional and anatomical peculiarities of constitution of women of mature age.Methods There was completed comprehensive anthropometric and bio-electrical survey of 651 mature women ( relative norm) living in the Moscow region .Results The quantitative distribution of women by somatotypological affiliation was revealed;anthropometric and body component composition in representatives of different somatotypes were defined .Conclusion Thus, the performed study revealed and quantiely character-ised the distribution of women according to their constitutional types in the studied population of mature age women living in Moscow region under the relative norm conditions .

  7. Ancestors of two-spirits: Historical depictions of Native North American gender-crossing women through critical discourse analysis.

    Science.gov (United States)

    Hemmilä, Anita

    2016-01-01

    Letters written by Christian men of European origin during the sixteenth-nineteenth centuries contain brief descriptions of gender-crossing individuals among indigenous Americans. Although now considered ethnocentrically biased because of the etic positioning of their authors, these historical sources are invaluable because they offer a glimpse of the ancestors of modern-day two-spirits. An application of critical discourse analysis to three depictions of gender-crossing females from the eighteenth and nineteenth centuries demonstrates that such women were favorably portrayed. These results differ dramatically from those obtained from my similar analysis of depictions of gender-crossing males. It also became evident that the three descriptions of gender-crossing women were not based on actual observations, but only on hearsay, which makes their use as primary sources questionable.

  8. Emerging Hopes

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    China looks to strategically important emerging industries for innovation-driven economic growthc hina will soon announce a decision to rev up seven strategically impor- tant emerging industries,said the National

  9. Emergency contraception

    Science.gov (United States)

    Morning-after pill; Postcoital contraception; Birth control - emergency; Plan B; Family planning - emergency contraception ... prevents pregnancy in the same way as regular birth control pills: By preventing or delaying the release of an ...

  10. Division G Commission 35: Stellar Constitution

    Science.gov (United States)

    Limongi, Marco; Lattanzio, John C.; Charbonnel, Corinne; Dominguez, Inma; Isern, Jordi; Karakas, Amanda; Leitherer, Claus; Marconi, Marcella; Shaviv, Giora; van Loon, Jacco

    2016-04-01

    Commission 35 (C35), ``Stellar Constitution'', consists of members of the International Astronomical Union whose research spans many aspects of theoretical and observational stellar physics and it is mainly focused on the comprehension of the properties of stars, stellar populations and galaxies. The number of members of C35 increased progressively over the last ten years and currently C35 comprises about 400 members. C35 was part of Division IV (Stars) until 2014 and then became part of Division G (Stars and Stellar Physics), after the main IAU reorganisation in 2015. Four Working Groups have been created over the years under Division IV, initially, and Division G later: WG on Active B Stars, WG on Massive Stars, WG on Abundances in Red Giant and WG on Chemically Peculiar and Related Stars. In the last decade the Commission had 4 presidents, Wojciech Dziembowski (2003-2006), Francesca D'Antona (2006-2009), Corinne Charbonnel (2009-2012) and Marco Limongi (2012-2015), who were assisted by an Organizing Committee (OC), usually composed of about 10 members, all of them elected by the C35 members and holding their positions for three years. The C35 webpage (http://iau-c35.stsci.edu) has been designed and continuously maintained by Claus Leitherer from the Space Telescope Institute, who deserves our special thanks. In addition to the various general information on the Commission structure and activities, it contains links to various resources, of interest for the members, such as stellar models, evolutionary tracks and isochrones, synthetic stellar populations, stellar yields and input physics (equation of state, nuclear cross sections, opacity tables), provided by various groups. The main activity of the C35 OC is that of evaluating, ranking and eventually supporting the proposals for IAU sponsored meetings. In the last decade the Commission has supported several meetings focused on topics more or less relevant to C35. Since the primary aim of this document is to

  11. Emergent Expertise?

    Science.gov (United States)

    McGivern, Patrick

    2014-01-01

    The concept of emergence appears in various places within the literature on expertise and expert practice. Here, I examine some of these applications of emergence in the light of two prominent accounts of emergence from the philosophy of science and philosophy of mind. I evaluate these accounts with respect to several specific contexts in which…

  12. Dynamic constitutional frameworks for DNA biomimetic recognition.

    Science.gov (United States)

    Catana, Romina; Barboiu, Mihail; Moleavin, Ioana; Clima, Lilia; Rotaru, Alexandru; Ursu, Elena-Laura; Pinteala, Mariana

    2015-02-07

    Linear and cross-linked dynamic constitutional frameworks generated from reversibly interacting linear PEG/core constituents and cationic sites shed light on the dominant coiling versus linear DNA binding behaviours, closer to the histone DNA binding wrapping mechanism.

  13. Romanian Constitutional Court and its Active Role in Assuring the Supremacy of the Constitution

    Directory of Open Access Journals (Sweden)

    Emil Balan

    2015-12-01

    Full Text Available Having read this paper, someone should have a general idea of some main constitutional concepts and principles and how they relate to the Romanian legal system. Romanian Constitutional Court is - according to art. 142 (1 of the Romanian Constitution - the guarantor of the Constitution’s supremacy. By virtue of this role, the Constitutional Court shall exercise general control of the compliance with the Constitution and the constitutionality of laws. The quality of guarantor allows the Constitutional Court to exercise an active role so that, throughout the provision of the decisions, but also throughout their considerations, which are imposed with equal force to all the legal issues/all subjects of law, it is put in view that the public authorities have the obligation of conform application of decisions, including of effects determined by them.

  14. The Democratic Constitutional State of Indonesia

    Directory of Open Access Journals (Sweden)

    Pan Mohamad Faiz

    2011-01-01

    Full Text Available The political reform in Indonesia started in 1998 when President Soeharto was forced to resign from his presidential office after 32 years in power. This momentum has transformed Indonesian political culture from an authoritarian state to the third largest democracy in the world after India and United States. It also led to Indonesian constitutional reform which was marked by the amendments of 1945 Constitution for the first time in 1999.

  15. South African court rejects country's new constitution.

    Science.gov (United States)

    1996-09-20

    Fundamental principles designed to ensure that South Africa's new constitution upholds a wide range of individual rights and freedoms and establishes a responsive government with a balanced separation of powers, including recognition of the role of traditional tribal leadership, were adopted into the current interim constitution shortly before the 1994 free elections which brought Nelson Mandela and the African National Congress to power. In a judgement issued on September 6, 1996, South Africa's Constitutional Court rejected the country's new draft constitution, arguing that it failed to meet the standards of nine of the 34 principles established at the Kempton Park negotiations. The Constitutional Assembly is comprised of a joint meeting of the National Assembly and Senate. One of the court's major objections to the constitution concerned the proposed structure of rule, which was seen to give inadequate power to South Africa's nine provinces as compared with the national government. However, the bill of rights was almost entirely upheld. The bill would create a favorable environment for legalized abortion and guarantee a universal right of access to health care, including reproductive health services

  16. Urgency of Attorney Governed by the Constitution

    Directory of Open Access Journals (Sweden)

    Rommy Patra

    2015-12-01

    Full Text Available Attorney existence in the Indonesian constitutional structure has a dilemma for this position. On one side is the Prosecutor’s law enforcement agencies to exercise power independently prosecution while on the other hand is part of a government institution under Law No. 16 of 2004 regarding the Attorney. The position of Attorney as an institution of government has been led to the independence of the Prosecutor is not optimal so that it appears stigma that the Prosecutor merely as a tool of the ruling power. In addition the terms of the arrangement just under the Act, the Attorney General has no legal standing as a constitutional organ that has the constitutional authority so that the current position does not reflect the urgency of its duties and functions. In an effort to organize the next Attorney institutions should be regulated directly by the Constitution. It is intended to make the Attorney as part of the main state organs have the same legal standing as other law enforcement agencies, the police and the courts (Supreme Court and Constitutional Court. As well as to strengthen and clarify the position as a state institution, prosecution authorities are focusing on the Attorney as central of authority, to fix the institutional relations between the members of law enforcement and related agencies and strengthen the independence of the Prosecutor in performing the function of prosecution in the constitutional structure of Indonesia.

  17. Ultima Ratio as a Constitutional Principle

    Directory of Open Access Journals (Sweden)

    Kaarlo Tuori

    2013-01-01

    Full Text Available The paper argues the criminal law notion of ultima ratio is an instance of a broader constitutional law principle of proportionality. However, ultima ratio is not the only principle relevant in a constitutional assessment of criminalization. The role of ultima ratio is to impose limitations on criminalization. But constitutional doctrines also exist which call for criminalization and might even be seen as establishing a criminalization obligation. The paper examines three constitutional counter weights to ultima ratio. The first of these is discussed in the context of state constitutions. This is the cluster of the interrelated constitutional doctrines of the horizontal effect of fundamental rights and the protective duty of the state, as well as the understanding of collective security as a basic right. These doctrines are analysed in the light of the praxis of the German Constitutional Court and the Finnish Constitutional Law Committee. The two other constitutional counterweights are discussed at the level of the transnational, European constitution. These are the principles of precaution and effectiveness. Este artículo defiende que el concepto de ultima ratio es una instancia más amplia del principio de proporcionalidad dentro del derecho constitucional. Sin embargo, el ultima ratio no es el único principio relevante en la valoración constitucional de la criminalización. El papel del ultima ratio es imponer límites a la criminalización. Pero también existen doctrinas constitucionales que exigen la criminalización e incluso dan pie a entender que obligan a establecer una pena. El documento examina tres contrapesos constitucionales al ultima ratio. En primer lugar, se analiza en el contexto de las constituciones estatales. Este es el conjunto de las doctrinas constitucionales interrelacionadas entre el efecto horizontal de los derechos fundamentales y el deber de protección del Estado, así como la asunción de la seguridad colectiva

  18. Constitutional law and international law at the turn of the century

    Directory of Open Access Journals (Sweden)

    JA Frowein

    1998-11-01

    Full Text Available Constitutional law and international law operate in simultaneous conjunction and reciprocal tension. Both fields seem to have overcome the great challenges of destruction and neglect in the course of the 20th century.Both after World War I and World War II the world experienced new waves of constitution making. In both cases the current German constitutions (the Weimar Constitution of 1919 and the Grundgesetz of 1949 were influential.Characteristic of constitution-making in this century, is the final victory of liberal constitutions based on the rule of law, the Rechtsstaat, fundamental rights, meaningful control of public powers and the establishment of constitutional courts.Following the destruction of World War II, the notion of the Sozialstaat emerged strongly in Germany. In contrast to the Constitution of the United States of America, the principle of the responsibility of the state for social justice has emerged in almost all new constitutions, including Russia, Poland, South Africa, Spain, Italy and Portugal.Where courts are given the mandate to interpret bills of rights, fundamental rights have been developed into foundation stones of the legal system. The presence in a Bill of Rights of restrictive clauses, is important for its analysis. Generally restrictive clauses in new constitutions try to limit the possibilities of restriction.The importance of constitutional rules establishing and legitimizing the political organs, must not be overlooked. Of particular importance is the degree of control over the head of state, a positive attitude among political actors towards the constitution and the protection of the interests of minorities in a democratic system.In the field of Public International Law much of Kant's ideal of an international confederation of peace has been realized. Since 1990 the United Nation's Security Council has shown the potential of becoming a directorate for the community of nations.International law has also been

  19. Enslaved Constitution: Obstructing the Freedom to Travel

    Directory of Open Access Journals (Sweden)

    Mitchell F. Crusto

    2008-04-01

    Full Text Available Does the Constitution protect a citizen’s intra-state travel (within a state from unjustified state prohibition? To date, the Supreme Court has not ruled directly on the issue, and many federal courts believe that the right to intrastate travel is not constitutionally protected. This Article explores the constitutional right of intra-state travel that is free from wrongful state infringement along public roadways by law-abiding citizens. Using critical legal history, this Article poses that federal courts’ denial of the right to intrastate travel consciously or unconsciously reflects the antebellum, Southern legal doctrine of people as property, which regulated the travel of enslaved African descendants.The constitutionality of intra-state travel arose most recently during the Hurricane Katrina Crisis when the City of Greta, Louisiana police barricaded a federal highway, denying would-be evacuees the ability to flee from the flooding City of New Orleans. In an ensuing action for infringement of the would-be evacuees’ constitutional right to intra-state travel, Federal District Judge Mary Ann Vial Lemmon dismissed the matter in Dickerson v. City of Gretna, holding that “[w]hile there is no doubt that a fundamental right of interstate travel exists, the Supreme Court has not ruled on whether a right of intra[-]state travel exists. This Court declines to find that there is a fundamental right to intra[-]state travel.” The Fifth Circuit affirmed the ruling.This Article recommends that when federal courts assess whether there is a constitutional right to intra-state travel, they should embrace the American paradigm of liberty and abandon the antebellum, Southern paradigm of enslavement. Consistent with Professor Derrick Bell’s “interestconvergence” principle, all Americans benefit when the Constitution protects the human rights of the least powerful American.

  20. A constitutive theory of reacting electrolyte mixtures

    Science.gov (United States)

    Costa Reis, Martina; Wang, Yongqi; Bono Maurizio Sacchi Bassi, Adalberto

    2013-11-01

    A constitutive theory of reacting electrolyte mixtures is formulated. The intermolecular interactions among the constituents of the mixture are accounted for through additional freedom degrees to each constituent of the mixture. Balance equations for polar reacting continuum mixtures are accordingly formulated and a proper set of constitutive equations is derived with basis in the Müller-Liu formulation of the second law of thermodynamics. Moreover, the non-equilibrium and equilibrium responses of the reacting mixture are investigated in detail by emphasizing the inner and reactive structures of the medium. From the balance laws and constitutive relations, the effects of molecular structure of constituents upon the fluid flow are studied. It is also demonstrated that the local thermodynamic equilibrium state can be reached without imposing that the set of independent constitutive variables is time independent, neither spatially homogeneous nor null. The resulting constitutive relations presented throughout this work are of relevance to many practical applications, such as swelling of clays, developing of bio and polymeric membranes, and use of electrorheological fluids in industrial processes. The first author acknowledges financial support from National Counsel of Technological and Scientific Development (CNPq) and German Academic Exchange Service (DAAD).

  1. Between constitution and interpretation: Identity as history

    Directory of Open Access Journals (Sweden)

    Hilt Annette

    2015-01-01

    Full Text Available The paper focuses on the possibilities to constitute meaning in the „borderline- situations“ (Jaspers of the social sphere, such as the loss of validity of orientation within and experience of reality in the socially shared structures of the lifeworld. On the one hand, I will refer to A. Schutz’ and his constitution-analysis of foreign understanding and of shared meaning; on the other hand, I bear onto I. Kertész literary project to narrate the biography of an Auschwitz-survivor as close to his experiential perspective as possible. I will focus both on the concept of constitution and of interpretation with respect to their enabling of the transcending of a typologized everyday’s world which suppresses subjective meaning and its individual articulation. The main guideline is the problem how identity – i.e. a life-story – is configured out of subjective meaning without recourse to everyday reality. A. Schutz’s and Th. Luckmann’s note on a range of social transcendences and on biographical categories referring to the constitution of a socially shared meaning offer a theoretical perspective for dealing with constitutive differences within the reach of understanding social meaning; Kertész’ narrative mode expandes this theoretical stance as it problematizes exemplary subjective experience.

  2. Health care law versus constitutional law.

    Science.gov (United States)

    Hall, Mark A

    2013-04-01

    National Federation of Independent Business v. Sebelius, the Supreme Court's ruling on the Patient Protection and Affordable Care Act, is a landmark decision - both for constitutional law and for health care law and policy. Others will study its implications for constitutional limits on a range of federal powers beyond health care. This article considers to what extent the decision is also about health care law, properly conceived. Under one view, health care law is the subdiscipline that inquires how courts and government actors take account of the special features of medicine that make legal or policy issues especially problematic - rather than regarding health care delivery and finance more generically, like most any other economic or social enterprise. Viewed this way, the opinions from the Court's conservative justices are mainly about general constitutional law principles. In contrast, Justice Ruth Bader Ginsburg's dissenting opinion for the four more liberal justices is just as much about health care law as it is about constitutional law. Her opinion gives detailed attention to the unique features of health care finance and delivery in order to inform her analysis of constitutional precedents and principles. Thus, the Court's multiple opinions give a vivid depiction of the compelling contrasts between communal versus individualistic conceptions of caring for those in need, and between health care and health insurance as ordinary commodities versus ones that merit special economic, social, and legal status.

  3. Politics of (In)visibility: Governance-Resistance and the Constitution of Refugee Subjectivities in Malaysia

    OpenAIRE

    Ansems De Vries, Leonie

    2016-01-01

    This article explores the relationality of governance and resistance in the context of the constitution of refugee subjectivities in Malaysia. Whilst recognising their precarity, the article moves away from conceiving of refugees merely as victims subjected to violence and control, and to contribute to an emerging body of literature on migrant resistance. Its contribution lies in examining practices of resistance, and the specific context in which they emerge, without conceptualising power-re...

  4. Cultural, social and economic rights in the Constitution corpus and Constitutional Court’s Case Law

    Directory of Open Access Journals (Sweden)

    Patricio Rubio

    2013-12-01

    Full Text Available This article deals with Cultural, Social and Economic Rights established in the Constitution and in Constitutional Case Law. So, after explaining its nature, state’s role according preservation and enforceability,relationship with other fundamental rights, among other key points, it isi ntended to answer, dealing with those rights, which of two scenarios have prevailed: internationalization of constitutional law or constitutionalization of international law.

  5. Constitutional Fundamentals of Conscription and Some Aspects of the Ordinary Legal Regulation of Constitutionality

    Directory of Open Access Journals (Sweden)

    Kenstavičienė Kristina

    2015-12-01

    Full Text Available Article 139 of the Constitution of the Republic of Lithuania is one of the constitutional fundamentals of state defense and stipulates the defense of the state as the right of citizens on the one hand and the duty on the other. This article of the Constitution gives the legislative power the right of discretion to detail by law the order of the implementation of citizens’ duty to perform military or alternative country defense service. Due to the reorganization of the armed forces into a professional and volunteer army, the issue of some ordinary regulation rules concerning the constitutionality of nationwide conscription, though at present suspended but not abolished, is becoming urgent. Though the Constitutional Court of the Republic of Lithuania presented their ruling on the constitutionality of the suspension of military conscription, it does not mean that all problems related to conscription have been settled. The aim of this article is to analyze the constitutional basis of nationwide conscription as well as the constitutionality of some ordinary regulation provisions related to nationwide conscription. Therefore, the issue to be analyzed is whether nationwide conscription, if it were to be implemented, complies with the constitutional principles of human equality and military justice1. Consequently, the question is posed how the constitutional objective of ensuring the defense of the state determines conscription. Because of the growing employment of the army abroad, yet the dwindling demand for conscripts, it should be explored whether the suspension of the nationwide conscription as a part of the defense reform is further feasible in order to guarantee the defense of the state. In answering the raised questions, the author will analyze the abundant and long-lasting constitutional doctrine of Germany which provides clarifications of the Basic Law, as the legal act of the establishing power, which can doubtless be of assistance in

  6. Dental Emergencies

    OpenAIRE

    Domb, Ivor

    1982-01-01

    Emergency dental problems can result from trauma, dental pathology, or from dental treatment itself. While the physician can treat many instances of dental trauma, the patient should see a dentist as soon as possible so that teeth can be saved. Emergency treatment of dental pathology usually involves relief of pain and/or swelling. Bleeding is the most frequent post-treatment emergency. The physician should be able to make the patient comfortable until definitive dental treatment can be avail...

  7. Extended constitutive laws for lamellar phases

    Directory of Open Access Journals (Sweden)

    Chi-Deuk Yoo

    2013-10-01

    Full Text Available Classically, stress and strain rate in linear viscoelastic materials are related by a constitutive relationship involving the viscoelastic modulus G(t. The same constitutive law, within Linear Response Theory, relates currents of conserved quantities and gradients of existing conjugate variables, and it involves the autocorrelation functions of the currents in equilibrium. We explore the consequences of the latter relationship in the case of a mesoscale model of a block copolymer, and derive the resulting relationship between viscous friction and order parameter diffusion that would result in a lamellar phase. We also explicitly consider in our derivation the fact that the dissipative part of the stress tensor must be consistent with the uniaxial symmetry of the phase. We then obtain a relationship between the stress and order parameter autocorrelation functions that can be interpreted as an extended constitutive law, one that offers a way to determine them from microscopic experiment or numerical simulation.

  8. A survey of unified constitutive theories

    Science.gov (United States)

    Chan, K. S.; Lindholm, U. S.; Bodner, S. R.; Walker, K. P.

    1985-01-01

    The state of the art of time temperature dependent elastic viscoplastic constitutive theories which are based on the unified approach werre assessed. This class of constitutive theories is characterized by the use of kinetic equations and internal variables with appropriate evolutionary equations for treating all aspects of inelastic deformation including plasticity, creep, and stress relaxation. More than 10 such unified theories which are shown to satisfy the uniqueness and stability criteria imposed by Drucker's postulate and Ponter's inequalities are identified. The theories are compared for the types of flow law, kinetic equation, evolutionary equation of the internal variables, and treatment of temperature dependence. The similarities and differences of these theories are outlined in terms of mathematical formulations and illustrated by comparisons of theoretical calculations with experimental results which include monotonic stress-strain curves, cyclic hysteresis loops, creep and stress relaxation rates, and thermomechanical loops. Numerical methods used for integrating these stiff time temperature dependent constitutive equations are reviewed.

  9. Constitutional developments in Latin American abortion law.

    Science.gov (United States)

    Bergallo, Paola; Ramón Michel, Agustina

    2016-11-01

    For most of the 20th Century, restrictive abortion laws were in place in continental Latin America. In recent years, reforms have caused a liberalizing shift, supported by constitutional decisions of the countries' high courts. The present article offers an overview of the turn toward more liberal rules and the resolution of abortion disputes by reference to national constitutions. For such purpose, the main legal changes of abortion laws in the last decade are first surveyed. Landmark decisions of the high courts of Argentina, Bolivia, Colombia, and Mexico are then analyzed. It is shown that courts have accepted the need to balance interests and competing rights to ground less restrictive laws. In doing so, they have articulated limits to protection of fetal interests, and basic ideas of women's dignity, autonomy, and equality. The process of constitutionalization has only just begun. Constitutional judgments are not the last word, but they are important contributions in reinforcing the legality of abortion.

  10. Acoustomechanical constitutive theory for soft materials

    Institute of Scientific and Technical Information of China (English)

    Fengxian Xin; Tian Jian Lu

    2016-01-01

    Acoustic wave propagation from surrounding medium into a soft material can generate acoustic radiation stress due to acoustic momentum transfer inside the medium and material, as well as at the interface between the two. To analyze acoustic-induced deformation of soft materials, we establish an acoustomechanical constitutive theory by com-bining the acoustic radiation stress theory and the nonlinear elasticity theory for soft materials. The acoustic radiation stress tensor is formulated by time averaging the momen-tum equation of particle motion, which is then introduced into the nonlinear elasticity constitutive relation to construct the acoustomechanical constitutive theory for soft materials. Considering a specified case of soft material sheet subjected to two counter-propagating acoustic waves, we demonstrate the nonlinear large deformation of the soft material and ana-lyze the interaction between acoustic waves and material deformation under the conditions of total reflection, acoustic transparency, and acoustic mismatch.

  11. Molecular karyotyping in human constitutional cytogenetics.

    Science.gov (United States)

    Sanlaville, Damien; Lapierre, Jean-Michel; Turleau, Catherine; Coquin, Aurélie; Borck, Guntram; Colleaux, Laurence; Vekemans, Michel; Romana, Serge Pierrick

    2005-01-01

    Using array CGH it is possible to detect very small genetic imbalances anywhere in the genome. Its usefulness has been well documented in cancer and more recently in constitutional disorders. In particular it has been used to detect interstitial and subtelomeric submicroscopic imbalances, to characterize their size at the molecular level and to define the breakpoints of chromosomal translocation. Here, we review the various applications of array CGH in constitutional cytogenetics. This technology remains expensive and the existence of numerous sequence polymorphisms makes its interpretation difficult. The challenge today is to transfer this technology in the clinical setting.

  12. The Constitution of a Transnational Policy Field

    DEFF Research Database (Denmark)

    Højbjerg, Erik; Frankel, Christian

    outside EU political and administrative control - in the constitution of the internal market. Second, the delegation raises important analytical questions concerning the identification of the institutional locus of European integration, when the realization of the political goals with the internal market...... is dependent on an inter-organizational coordination between the EU and ESO. Applying the analytical concept of a `policy field' the analysis shows how the completion of the internal market fundamentally challenges institutionalized conceptions of the role of politics in constituting markets.Keywords: Internal...

  13. Catholic Modernity and the Italian Constitution

    DEFF Research Database (Denmark)

    Thomassen, Bjørn; Forlenza, Rosario

    2016-01-01

    This article analyzes the Catholic contribution to the Italian republican and democratic Constitution of 1948. The focus is on the specific way in which the Italian citizen became symbolically coded as a ‘person’ and not as an ‘individual’, inspired by Catholic social philosophy. The Catholic...... project for the new Constitution had a considerable impact on modern Italian culture and politics and on the building of a modern mass democracy and welfare state. During the crucial historical juncture that followed the collapse of Fascism, Catholic politicians and intellectuals sought to interpret...

  14. Emergency Shelters

    DEFF Research Database (Denmark)

    Popovic Larsen, Olga; Lee, Daniel Sang-Hoon; Eskemose Andersen, Jørgen;

    2013-01-01

    The report gives all the research, teaching, seminars carried in the duration of the shelter cluster. It concludes with proposing relevant research agendas in the field of emergency architecture......The report gives all the research, teaching, seminars carried in the duration of the shelter cluster. It concludes with proposing relevant research agendas in the field of emergency architecture...

  15. Vascular emergencies.

    Science.gov (United States)

    Semashko, D C

    1997-01-01

    This article reviews the initial assessment and emergent management of several common as well as uncommon vascular emergencies. Aortic dissection, aneurysms, and arterial occlusive disease are familiar but challenging clinical entities. Less frequently encountered conditions are also discussed including an aortic enteric fistula, mesenteric venous thrombosis, phlegmasia alba dolens, and subclavian vein thrombosis.

  16. Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence.

    Directory of Open Access Journals (Sweden)

    Julien Y Dutheil

    2015-08-01

    Full Text Available The human and chimpanzee X chromosomes are less divergent than expected based on autosomal divergence. We study incomplete lineage sorting patterns between humans, chimpanzees and gorillas to show that this low divergence can be entirely explained by megabase-sized regions comprising one-third of the X chromosome, where polymorphism in the human-chimpanzee ancestral species was severely reduced. We show that background selection can explain at most 10% of this reduction of diversity in the ancestor. Instead, we show that several strong selective sweeps in the ancestral species can explain it. We also report evidence of population specific sweeps in extant humans that overlap the regions of low diversity in the ancestral species. These regions further correspond to chromosomal sections shown to be devoid of Neanderthal introgression into modern humans. This suggests that the same X-linked regions that undergo selective sweeps are among the first to form reproductive barriers between diverging species. We hypothesize that meiotic drive is the underlying mechanism causing these two observations.

  17. RSL Class I Genes Controlled the Development of Epidermal Structures in the Common Ancestor of Land Plants.

    Science.gov (United States)

    Proust, Hélène; Honkanen, Suvi; Jones, Victor A S; Morieri, Giulia; Prescott, Helen; Kelly, Steve; Ishizaki, Kimitsune; Kohchi, Takayuki; Dolan, Liam

    2016-01-11

    The colonization of the land by plants, sometime before 470 million years ago, was accompanied by the evolution tissue systems [1-3]. Specialized structures with diverse functions-from nutrient acquisition to reproduction-derived from single cells in the outermost layer (epidermis) were important sources of morphological innovation at this time [2, 4, 5]. In extant plants, these structures may be unicellular extensions, such as root hairs or rhizoids [6-9], or multicellular structures, such as asexual propagules or secretory hairs (papillae) [10-12]. Here, we show that a ROOTHAIR DEFECTIVE SIX-LIKE (RSL) class I basic helix-loop-helix transcription factor positively regulates the development of the unicellular and multicellular structures that develop from individual cells that expand out of the epidermal plane of the liverwort Marchantia polymorpha; mutants that lack MpRSL1 function do not develop rhizoids, slime papillae, mucilage papillae, or gemmae. Furthermore, we discovered that RSL class I genes are also required for the development of multicellular axillary hairs on the gametophyte of the moss Physcomitrella patens. Because class I RSL proteins also control the development of rhizoids in mosses and root hairs in angiosperms [13, 14], these data demonstrate that the function of RSL class I genes was to control the development of structures derived from single epidermal cells in the common ancestor of the land plants. Class I RSL genes therefore controlled the generation of adaptive morphological diversity as plants colonized the land from the water.

  18. The cult of amphioxus in German Darwinism; or, our gelatinous ancestors in Naples' blue and balmy bay.

    Science.gov (United States)

    Hopwood, Nick

    2015-01-01

    Biologists having rediscovered amphioxus, also known as the lancelet or Branchiostoma, it is time to reassess its place in early Darwinist debates over vertebrate origins. While the advent of the ascidian-amphioxus theory and challenges from various competitors have been, documented, this article offers a richer account of the public appeal of amphioxus as a primitive ancestor. The focus is on how the 'German Darwin' Ernst Haeckel persuaded general magazine and newspaper readers to revere this "flesh of our flesh and blood of our blood", and especially on Das neue Laienbrevier des Haeckelismus (The new lay breviary of Haeckelism) by Moritz Reymond with cartoons by Fritz Steub. From the late 1870s these successful little books of verse introduced the Neapolitan discoveries that made the animal's name and satirized Haeckel's rise as high priest of its cult. One song is reproduced and translated here, with a contemporary "imitation" by the Canadian palaeontologist Edward John Chapman, and extracts from others. Predating the American "It's a long way from amphioxus" by decades, these rhymes dramatize neglected 'species politics' of Darwinism and highlight the roles of humour in negotiating evolution.

  19. Evolution from a respiratory ancestor to fill syntrophic and fermentative niches: comparative fenomics of six Geobacteraceae species

    Directory of Open Access Journals (Sweden)

    Lovley Derek R

    2009-03-01

    Full Text Available Abstract Background The anaerobic degradation of organic matter in natural environments, and the biotechnical use of anaerobes in energy production and remediation of subsurface environments, both require the cooperative activity of a diversity of microorganisms in different metabolic niches. The Geobacteraceae family contains members with three important anaerobic metabolisms: fermentation, syntrophic degradation of fermentation intermediates, and anaerobic respiration. Results In order to learn more about the evolution of anaerobic microbial communities, the genome sequences of six Geobacteraceae species were analyzed. The results indicate that the last common Geobacteraceae ancestor contained sufficient genes for anaerobic respiration, completely oxidizing organic compounds with the reduction of external electron acceptors, features that are still retained in modern Geobacter and Desulfuromonas species. Evolution of specialization for fermentative growth arose twice, via distinct lateral gene transfer events, in Pelobacter carbinolicus and Pelobacter propionicus. Furthermore, P. carbinolicus gained hydrogenase genes and genes for ferredoxin reduction that appear to permit syntrophic growth via hydrogen production. The gain of new physiological capabilities in the Pelobacter species were accompanied by the loss of several key genes necessary for the complete oxidation of organic compounds and the genes for the c-type cytochromes required for extracellular electron transfer. Conclusion The results suggest that Pelobacter species evolved parallel strategies to enhance their ability to compete in environments in which electron acceptors for anaerobic respiration were limiting. More generally, these results demonstrate how relatively few gene changes can dramatically transform metabolic capabilities and expand the range of environments in which microorganisms can compete.

  20. Institute of constitutional revision in the Constitution of the Republic of Albania, comparative view

    Directory of Open Access Journals (Sweden)

    Makbule Çeço

    2014-07-01

    Full Text Available In its very dynamic essence, a democratic society bears the need for continuous reformation and perfection, and that is why the application of reforms represents an inseparable feature for this type of society. The consolidation of the rule of law, the institutional independence, and the cause of justice itself comprise, inter alia, the need for constitutional revision. This study puts forward a theoretical-historical comparative view of the relevant and dynamic issue of the institute of constitutional revision in the framework of the Constitution of the Republic of Albania, as a complex process accompanied by limitations on constitutional revision. The historical evolution of constitutional drafting, modern constitutions, relevant issues, political and social circumstances as well as drafting and adoption procedures, dynamism of constitutions to cope with the course of time achieved by revisions for the purpose of their stability as well as consolidation of the role of constitutions as a factor that facilitates and precedes social development, comprise the pillar of this study addressed in a comparative point of view.

  1. Ethnicity and constitutionalism in contemporary Ethiopia

    NARCIS (Netherlands)

    Abbink, J.

    1997-01-01

    According to the policy of the government of the Ethiopian Peoples' Revolutionary Democratic Front (EPRDF), ethnic identity is the ideological basis of Ethiopia's political organization and administration and as such has been enshrined in the Federal Constitution of December 1994. Yet the Constituti

  2. The Constitutionality of DNA Sampling of Arrestees

    Directory of Open Access Journals (Sweden)

    Anip Patel

    2012-12-01

    Full Text Available This article addresses whether the DNA Act (which requires DNA samples from arrestees passes constitutional muster. I argue that the act is constitutional and that if society believes the collection of DNA from arrestees violates an individual’s privacy, it should seek legislative resolution and not seek the protection of the Fourth Amendment of the Constitution. Throughout my analysis, I demonstrate why DNA collection is constitutional and how it is necessary. Part I of this article examines the history of DNA sampling, case law establishing an arrestee’s expectation of privacy, and the applicable Fourth Amendment tests. Part II examines the arguments for and against DNA sampling by considering case law at the state and federal level, and explores the significance of junk DNA and the treatment of abandoned DNA. Part III is the personal analysis section, which argues that the totality of circumstances test is the proper test. I apply the test to determine that there is minimal intrusion of an arrestee’s expectation of privacy through DNA sampling, a legitimate governmental interest, and that warrants are unnecessary. Further, the section demonstrates why DNA sampling is a natural progression from fingerprint collection, and the section analyzes abandoned DNA and DNA sampling. Part IV concludes the article by stating that the Fourth Amendment is not violated and that society must turn to Congress to seek greater protection.

  3. Constitutive laws, tensorial invariance and chocolate cake

    Energy Technology Data Exchange (ETDEWEB)

    Rundle, J.B.; Passman, S.L.

    1982-01-01

    Although constitutive modeling is a well-established branch of mathematics which has found wide industrial application, geophysicists often do not take full advantage of its known results. We present a synopsis of the theory of constitutive modeling, couched in terms of the simple material, which has been extensively studied and is complex enough to include most of the correct models proposed to describe the behavior of geological materials. Critical in the development of the theory are various invariance requirements, the principal ones being coordinate invariance, peer group invariance (isotropy), and frame-indifference. Each places distinct restrictions on constitutive equations. A noncomprehensive list of properly invariant and commonly used constitutive equations is given. To exemplify use of the equations, we consider two problems in detail: steady extension, which models the commonly performed constant strain rate triaxial test, and simple shearing. We note that each test is so restricted kinematically that only the most trivial aspects of material behavior are manifested in these tests, no matter how complex the material. Furthermore, the results of one test do not generally determine the results of the other.

  4. Constitutional interpretation : a view from a distance

    NARCIS (Netherlands)

    Peters, Richard

    2011-01-01

    This paper explores how the notion of distance works in the practice of interpretation by studying the philosophical underpinnings of the originalism debate in American constitutionalism. Focusing on some of its most important spokespeople, the paper shows that they start from the historicist presup

  5. From particle simulations to macroscopic constitutive relations

    NARCIS (Netherlands)

    Göncü, F.; Luding, S.

    2010-01-01

    The goal is to determine the constitutive behavior of granular packings under various deformations (isotropic and anisotropic) from particle simulations. For this we consider deformations, stress, structure and the contact forces as the basis. In a previous study [6,7] we investigated using DEM, the

  6. Respecting Constitutional Identity in the EU

    NARCIS (Netherlands)

    Besselink, Leonard F.M.

    2012-01-01

    This essay discusses the Sayn-Wittgenstein judgment of the ECJ, in which for the first time an appeal to the constitutional identity of a member state in order to limit a right under EU law, under Article 4(2) TEU, i.e. the duty for the EU to respect the national identities of the Member States, was

  7. The parameters of constitutional conflict after Melloni

    NARCIS (Netherlands)

    Besselink, L.F.M.

    2014-01-01

    The judgment of the Court of Justice of the EU in Melloni makes clear that primacy of EU law is not about citizens’ rights: even the core of their constitutional rights under national law has to be set aside in favour of the "primacy, unity and effectiveness" of EU law. Melloni extends the duty to s

  8. A New Perspective on Teaching Constitutional Law

    Science.gov (United States)

    Rosenblum, Robert

    1977-01-01

    The author suggests that a major failure of most law schools and traditional undergraduate constitutional law courses is that they omit an adequate analysis of the political nature of the judicial process. Political influences on a variety of court cases are discussed. (LBH)

  9. Globalization of Constitutional Law and Civil Rights.

    Science.gov (United States)

    Weissbrodt, David

    1993-01-01

    Two issues are discussed: (1) reasons for raising global and international human rights issues in constitutional law, civil rights, and administrative law courses in United States law schools; and (2) barriers to globalization of courses and ways to overcome them. (MSE)

  10. Rapping the 27 Amendments to the Constitution

    Science.gov (United States)

    Knaresborough, Adam

    2009-01-01

    Early in the year, the students of history and government at Mountain View High School in Stafford, Virginia, began to devise hand motions to help memorize the 27 amendments to the Constitution for government class. Three students in the school who are interested in hip hop music then suggested composing a rap song about the topic. Working with…

  11. Science popularization and the Indian constitution - Correspondence

    Digital Repository Service at National Institute of Oceanography (India)

    Varkey, M.J.

    Article 51A (h) of the Indian Constitution reads as follows, (citizens have a duty) to develop the scientific temper, humanism and the spirit of inquiry and reform. This item under basic duties is of great importance to those popularising science...

  12. Crushed-salt constitutive model update

    Energy Technology Data Exchange (ETDEWEB)

    Callahan, G.D.; Loken, M.C.; Mellegard, K.D. [RE/SPEC Inc., Rapid City, SD (United States); Hansen, F.D. [Sandia National Labs., Albuquerque, NM (United States)

    1998-01-01

    Modifications to the constitutive model used to describe the deformation of crushed salt are presented in this report. Two mechanisms--dislocation creep and grain boundary diffusional pressure solutioning--defined previously but used separately are combined to form the basis for the constitutive model governing the deformation of crushed salt. The constitutive model is generalized to represent three-dimensional states of stress. New creep consolidation tests are combined with an existing database that includes hydrostatic consolidation and shear consolidation tests conducted on Waste Isolation Pilot Plant and southeastern New Mexico salt to determine material parameters for the constitutive model. Nonlinear least-squares model fitting to data from the shear consolidation tests and a combination of the shear and hydrostatic consolidation tests produced two sets of material parameter values for the model. The change in material parameter values from test group to test group indicates the empirical nature of the model but demonstrates improvement over earlier work with the previous models. Key improvements are the ability to capture lateral strain reversal and better resolve parameter values. To demonstrate the predictive capability of the model, each parameter value set was used to predict each of the tests in the database. Based on the fitting statistics and the ability of the model to predict the test data, the model appears to capture the creep consolidation behavior of crushed salt quite well.

  13. The EU and Constitutionalism in Egypt

    DEFF Research Database (Denmark)

    Seeberg, Peter

    2013-01-01

    in the context of Egyptian-European relations. The article argues that the EU policies, which earlier have been dominated by a pragmatic approach towards the Mubarak regime, now have to be rethought considering an Egyptian polity, where the contours of a new constitutionalism are developing....

  14. Fetal Pain, Abortion, Viability and the Constitution

    OpenAIRE

    Cohen, I. Glenn; Sayeed, Sadath Ali

    2011-01-01

    In early 2010, the Nebraska state legislature passed a new abortion restricting law asserting a new, compelling state interest in preventing fetal pain. In this article, we review existing constitutional abortion doctrine and note difficulties presented by persistent legal attention to a socially derived viability construct. We then offer a substantive biological, ethical, and legal critique of the new fetal pain rationale.

  15. Fetal pain, abortion, viability, and the Constitution.

    Science.gov (United States)

    Cohen, I Glenn; Sayeed, Sadath

    2011-01-01

    In early 2010, the Nebraska state legislature passed a new abortion restricting law asserting a new, compelling state interest in preventing fetal pain. In this article, we review existing constitutional abortion doctrine and note difficulties presented by persistent legal attention to a socially derived viability construct. We then offer a substantive biological, ethical, and legal critique of the new fetal pain rationale.

  16. Constitutional characteristics of zones of prostate structure

    Directory of Open Access Journals (Sweden)

    Vinnik Y.Y.

    2012-06-01

    Full Text Available The research article is devoted to the study of structural characteristics of prostate according to the young men constitution. Materials and methods: 540 vertical and horizontal sections of prostate have been investigated. Results: Size characteristics of prostate have been established in men of different somatotypes

  17. The constitutive equation for membrane tether extraction.

    Science.gov (United States)

    Chen, Yong; Yao, Da-Kang; Shao, Jin-Yu

    2010-12-01

    Membrane tethers or nanotubes play a critical role in a variety of cellular and subcellular processes such as leukocyte rolling and intercellular mass transport. The current constitutive equations that describe the relationship between the pulling force and the tether velocity during tether extraction have serious limitations. In this article, we propose a new phenomenological constitutive equation that captures all known characteristics of nanotube formation, including nonlinearity, nonzero threshold force, and possible negative tether velocity. We used tether extraction from endothelial cells as a prototype to illustrate how to obtain the material constants in the constitutive equation. With the micropipette aspiration technique, we measured tether pulling forces at both positive and negative tether velocities. We also determined the threshold force of 55 pN experimentally for the first time. This new constitutive equation unites two established ones and provides us a unified platform to better understand not only the physiological role of tether extraction during leukocyte rolling and intercellular or intracellular transport, but also the physics of membrane tether growth or retraction.

  18. The European Constitution; La constitucion Europea

    Energy Technology Data Exchange (ETDEWEB)

    Morales, A.

    2004-07-01

    The convention on the Future of Europe, convened after the European Council of Laeken, in December 2001, has submitted the complete project to the European Council for a Treaty to create a Constitution for Europe which is aimed at developing an economic and political European Union, defining its specific competencies and the roles of the various national parliaments. (Author)

  19. Strategic Implications of Japan Amending Its Constitution

    Science.gov (United States)

    2008-12-09

    quo. Under the 11 leadership of Prime Ministers Junichiro Koizumi (2001-2006) and Shinzo Abe (2006- 2007), the movement to amend Article 9 picked up...amend the Constitution, Prime Minister Abe abruptly resigned in 2007 amidst scandals unrelated to his Article 9 ambitions. His successor, Yasuo Fukuda

  20. The Political Theory of Mencius on Constitutionalism

    Institute of Scientific and Technical Information of China (English)

    饶龙霞

    2016-01-01

    The traditional studies think that Mencius represents the Confucian idealism. Based on the traditional interpretation of Mencius, this article will reconstructed the Mencius thought of rule of virtue, and analysis Mencius thoughts of rule of virtue from the perspective of constitutionalism.

  1. Commemorating the Ancestors

    Science.gov (United States)

    Mack, Stevie; Williams, Kathleen

    2010-01-01

    The festivals of Mexico are renowned for their colorful decorations, energetic music, exuberant parades, and cultural significance. "Los Dias de los Muertos," the Days of the Dead, is no exception. Often misunderstood by those who live elsewhere, this festival commemorating the dead is one of Mexico's most important holidays. As Americans prepare…

  2. Comparison of Constitutional Spirit Between United States and China

    Institute of Scientific and Technical Information of China (English)

    杨琅琅

    2007-01-01

    This paper compares the differences in constitutional spirit between United States and China, and then brings out the influence of the constitutional spirit in United States to the constitutional spirit in China.

  3. Emergency contraception.

    Science.gov (United States)

    Van Look, P F; von Hertzen, H

    1993-01-01

    The term 'emergency contraception', as employed in this paper, refers to methods that are used as emergency procedures to prevent pregnancy following unprotected intercourse. Alternative, less appropriate, terms are postcoital and 'morning-after' contraception. References to postcoital preparations can be found as far back as 1500 BC in Egyptian papyri, but it was not until fairly recently that contraceptive research has been able to at least partially fulfill that need. The development of hormonal methods of emergency contraception goes back to the 1960s when the first human trials of postcoitally administered high-dose oestrogens were undertaken. Combined oestrogen- progestogen combination therapy (the so-called Yuzpe regimen) was introduced in the early 1970s, while the postcoital insertion of an intrauterine contraceptive device (IUD) for emergency contraception was first reported in 1976. Other compounds that have been tested more recently include levonorgestrel, the antiprogestogen mifepristone, and danazol. Although there is some debate about the magnitude of the protective effect, few people question the important role that emergency contraception can play in preventing unwanted pregnancy and hence maternal mortality and morbidity resulting from unsafe abortion. Given that the most often used methods of emergency contraception, namely the Yuzpe regimen and postcoital insertion of an IUD, rely on technology that has been available for some 30 years, family planning programmes that claim to be concerned with improving women's reproductive health, cannot really be excused if they do not provide emergency contraception as part of their routine services.

  4. Constitutive Response of Microbial Induced Calcite Precipitation Cemented Sands

    Science.gov (United States)

    Feng, Kai

    In the last decade, microbial induced calcite precipitation (MICP) emerged as a novel technique for implementing soil improvement in an environmentally-friendly and economically beneficial manner. However, the mechanical behavior and constitutive response of these materials are still not fully explored by researchers. In this dissertation, the characteristics of MICP cemented sands are investigated through numerical modelling and experimental tests, including macro and micro tests under both static and dynamic loading. In the first part, the mechanical behavior of MICP cemented sands were probed using monotonic load testing and the existence of calcite precipitation was verified by scanning electron microscopy, with this behavior compared to traditionally cemented soil and naturally cemented soil. Both MICP cementation and traditional cementation were verified to be effective in the increase of stiffness and strength, and unique characteristic of MICP cemented soil was highlighted.

  5. Emergency Contraception

    Science.gov (United States)

    ... the pill that contains ulipristal acetate reduces the risk of pregnancy more effectively than pills that contain levonorgestrel.It is important to remember that emergency contraceptive pills will not prevent pregnancy if you have ...

  6. Eye emergencies

    Science.gov (United States)

    ... eds. Duane's Foundations of Clinical Ophthalmology . Philadelphia, PA: Lippincott Williams and Wilkins; 2013:vol. 3, chap 6. ... Practice of Emergency Medicine . 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2009:chap 54-61. Sharma R, ...

  7. CAN THE MUSLIM WORLD BORROW FROM INDONESIAN CONSTITUTIONAL REFORM? A Comparative Constitutional Approach

    Directory of Open Access Journals (Sweden)

    Nadirsyah Hosen

    2007-06-01

    Full Text Available This paper attempts to analytically examine the possibility of constitutional borrowing for the Muslim world regardless the differences in history, system, culture, language, and cha­racteristics. It discusses this issue by looking at the arguments put forth by the oppo­nents of comparative cons­titutional interpre­tation and their counter arguments. It will consider materials from Canada, USA, South Africa, Singapore, Malaysia, and Hungary, taking the position that constitutional borrowing can be justified. The paper argues that the 1999-2002 Indonesian constitutional reform should be taken into account by other Muslim countries in undertaking their constitutional reform. The substantive approach of the Shari‘ah that has been used in Indonesia has shown that Muslim world can reform its constitutions without the “assistance” of Western foreign policy. Indo­nesian constitutional reform has demonstrated that Islamic constitutionalism comes from within Islamic teaching and the Islamic community itself; it is a home grown product.

  8. Emerging boundaries

    DEFF Research Database (Denmark)

    Løvschal, Mette

    2014-01-01

    This article proposes a processual ontology for the emergence of man-made, linear boundaries across northwestern Europe, particularly in the first millennium BC. Over a significant period of time, these boundaries became new ways of organizing the landscape and settlements—a phenomenon that has...... of this phenomenon emerged along equivalent trajectories. At the same time, variation in the regional incorporation of these linear phenomena points toward situation-specific applications and independent development....

  9. EMERGENCY CALLS

    CERN Multimedia

    2001-01-01

    IN URGENT NEED OF A DOCTOR GENEVA EMERGENCY SERVICES GENEVA AND VAUD 144 FIRE BRIGADE 118 POLICE 117 CERN FIREMEN 767-44-44 ANTI-POISONS CENTRE Open 24h/24h 01-251-51-51 Patient not fit to be moved, call family doctor, or: GP AT HOME, open 24h/24h 748-49-50 Association Of Geneva Doctors Emergency Doctors at home 07h-23h 322 20 20 Patient fit to be moved: HOPITAL CANTONAL CENTRAL 24 Micheli-du-Crest 372-33-11 ou 382-33-11 EMERGENCIES 382-33-11 ou 372-33-11 CHILDREN'S HOSPITAL 6 rue Willy-Donzé 372-33-11 MATERNITY 32 bvd.de la Cluse 382-68-16 ou 382-33-11 OPHTHALMOLOGY 22 Alcide Jentzer 382-33-11 ou 372-33-11 MEDICAL CENTRE CORNAVIN 1-3 rue du Jura 345 45 50 HOPITAL DE LA TOUR Meyrin EMERGENCIES 719-61-11 URGENCES PEDIATRIQUES 719-61-00 LA TOUR MEDICAL CENTRE 719-74-00 European Emergency Call 112 FRANCE EMERGENCY SERVICES 15 FIRE BRIGADE 18 POLICE 17 CERN FIREMEN AT HOME 00-41-22-767-44-44 ANTI-POISONS CENTRE Open 24h/24h 04-72-11-69-11 All doctors ...

  10. Anorectal emergencies.

    Science.gov (United States)

    Lohsiriwat, Varut

    2016-07-14

    Anorectal emergencies refer to anorectal disorders presenting with some alarming symptoms such as acute anal pain and bleeding which might require an immediate management. This article deals with the diagnosis and management of common anorectal emergencies such as acutely thrombosed external hemorrhoid, thrombosed or strangulated internal hemorrhoid, bleeding hemorrhoid, bleeding anorectal varices, anal fissure, irreducible or strangulated rectal prolapse, anorectal abscess, perineal necrotizing fasciitis (Fournier gangrene), retained anorectal foreign bodies and obstructing rectal cancer. Sexually transmitted diseases as anorectal non-surgical emergencies and some anorectal emergencies in neonates are also discussed. The last part of this review dedicates to the management of early complications following common anorectal procedures that may present as an emergency including acute urinary retention, bleeding, fecal impaction and anorectal sepsis. Although many of anorectal disorders presenting in an emergency setting are not life-threatening and may be successfully treated in an outpatient clinic, an accurate diagnosis and proper management remains a challenging problem for clinicians. A detailed history taking and a careful physical examination, including digital rectal examination and anoscopy, is essential for correct diagnosis and plan of treatment. In some cases, some imaging examinations, such as endoanal ultrasonography and computerized tomography scan of whole abdomen, are required. If in doubt, the attending physicians should not hesitate to consult an expert e.g., colorectal surgeon about the diagnosis, proper management and appropriate follow-up.

  11. Horizontal transfer of a subtilisin gene from plants into an ancestor of the plant pathogenic fungal genus Colletotrichum.

    Science.gov (United States)

    Armijos Jaramillo, Vinicio Danilo; Vargas, Walter Alberto; Sukno, Serenella Ana; Thon, Michael R

    2013-01-01

    The genus Colletotrichum contains a large number of phytopathogenic fungi that produce enormous economic losses around the world. The effect of horizontal gene transfer (HGT) has not been studied yet in these organisms. Inter-Kingdom HGT into fungal genomes has been reported in the past but knowledge about the HGT between plants and fungi is particularly limited. We describe a gene in the genome of several species of the genus Colletotrichum with a strong resemblance to subtilisins typically found in plant genomes. Subtilisins are an important group of serine proteases, widely distributed in all of the kingdoms of life. Our hypothesis is that the gene was acquired by Colletotrichum spp. through (HGT) from plants to a Colletotrichum ancestor. We provide evidence to support this hypothesis in the form of phylogenetic analyses as well as a characterization of the similarity of the subtilisin at the primary, secondary and tertiary structural levels. The remarkable level of structural conservation of Colletotrichum plant-like subtilisin (CPLS) with plant subtilisins and the differences with the rest of Colletotrichum subtilisins suggests the possibility of molecular mimicry. Our phylogenetic analysis indicates that the HGT event would have occurred approximately 150-155 million years ago, after the divergence of the Colletotrichum lineage from other fungi. Gene expression analysis shows that the gene is modulated during the infection of maize by C. graminicola suggesting that it has a role in plant disease. Furthermore, the upregulation of the CPLS coincides with the downregulation of several plant genes encoding subtilisins. Based on the known roles of subtilisins in plant pathogenic fungi and the gene expression pattern that we observed, we postulate that the CPLSs have an important role in plant infection.

  12. Horizontal transfer of a subtilisin gene from plants into an ancestor of the plant pathogenic fungal genus Colletotrichum.

    Directory of Open Access Journals (Sweden)

    Vinicio Danilo Armijos Jaramillo

    Full Text Available The genus Colletotrichum contains a large number of phytopathogenic fungi that produce enormous economic losses around the world. The effect of horizontal gene transfer (HGT has not been studied yet in these organisms. Inter-Kingdom HGT into fungal genomes has been reported in the past but knowledge about the HGT between plants and fungi is particularly limited. We describe a gene in the genome of several species of the genus Colletotrichum with a strong resemblance to subtilisins typically found in plant genomes. Subtilisins are an important group of serine proteases, widely distributed in all of the kingdoms of life. Our hypothesis is that the gene was acquired by Colletotrichum spp. through (HGT from plants to a Colletotrichum ancestor. We provide evidence to support this hypothesis in the form of phylogenetic analyses as well as a characterization of the similarity of the subtilisin at the primary, secondary and tertiary structural levels. The remarkable level of structural conservation of Colletotrichum plant-like subtilisin (CPLS with plant subtilisins and the differences with the rest of Colletotrichum subtilisins suggests the possibility of molecular mimicry. Our phylogenetic analysis indicates that the HGT event would have occurred approximately 150-155 million years ago, after the divergence of the Colletotrichum lineage from other fungi. Gene expression analysis shows that the gene is modulated during the infection of maize by C. graminicola suggesting that it has a role in plant disease. Furthermore, the upregulation of the CPLS coincides with the downregulation of several plant genes encoding subtilisins. Based on the known roles of subtilisins in plant pathogenic fungi and the gene expression pattern that we observed, we postulate that the CPLSs have an important role in plant infection.

  13. Classification of pmoA amplicon pyrosequences using BLAST and the lowest common ancestor method in MEGAN

    Directory of Open Access Journals (Sweden)

    Marc Gregory Dumont

    2014-02-01

    Full Text Available The classification of high-throughput sequencing data of protein-encoding genes is not as well established as for 16S rRNA. The objective of this work was to develop a simple and accurate method of classifying large datasets of pmoA sequences, a common marker for methanotrophic bacteria. A taxonomic system for pmoA was developed based on a phylogenetic analysis of available sequences. The taxonomy incorporates the known diversity of pmoA present in public databases, including both sequences from cultivated and uncultivated organisms. Representative sequences from closely related genes, such as those encoding the bacterial ammonia monooxygenase, were also included in the pmoA taxonomy. In total, 53 low-level taxa (genus-level are included. Using previously published datasets of high-throughput pmoA amplicon sequence data, we tested two approaches for classifying pmoA: a naïve Bayesian classifier and BLAST. Classification of pmoA sequences based on BLAST analyses was performed using the lowest common ancestor (LCA algorithm in MEGAN, a software program commonly used for the analysis of metagenomic data. Both the naïve Bayesian and BLAST methods were able to classify pmoA sequences and provided similar classifications; however, the naïve Bayesian classifier was prone to misclassifying contaminant sequences present in the datasets. Another advantage of the BLAST/LCA method was that it provided a user-interpretable output and enabled novelty detection at various levels, from highly divergent pmoA sequences to genus-level novelty.  

  14. Thermodynamic watershed hydrological model: Constitutive relationship

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The representative elementary watershed (REW) approach proposed by Reggiani et al. was the first attempt to develop scale adaptable equations applicable directly at the macro scale. Tian et al. extended the initial definition of REW for simulating the energy related processes, and re-organized the deriving procedure of balance equations so that additional sub-regions and substances could be easily incorpo-rated. The resultant ordinary differential equation set can simulate various hydro-logical processes in a physically reasonable way. However, constitutive and geo-metric relationships have not been developed for Tian et al.’s equation set, which are necessary for the thermodynamic watershed hydrological model to apply in hydrological modeling practice. In this work, the constitutive equations for mass exchange terms and momentum exchange terms were developed as well as geo-metric relationships. The closed ordinary differential equation set with nine equa-tions was finally obtained.

  15. Mechanism of constitution liquid film migration

    Energy Technology Data Exchange (ETDEWEB)

    Zuo, Hongjun [Univ. of Alabama, Birmingham, AL (United States)

    1999-06-01

    Liquid film migration (LFM) in liquid phase sintering classically involves a large metastable liquid volume adjacent to solid, and migration occurs at an isolated solid-liquid (S-L) interface. Constitutional liquid film migration (CLFM), discovered in alloy 718, has major characteristics similar to those of LFM, except that the metastable liquid is from the constitutional liquation of precipitates on the grain boundary. The similarity between LFM and CLFM has led to the theory that coherency lattice strain responsible for LFM is also responsible for CLFM. The coherency strain hypothesis was tested in this study by evaluating whether the Hillert model of LFM would also apply for CLFM. Experimental results of CLFM in alloy 718 showed that migration velocity followed the trend predicted by the Hillert model. This indicates that the coherency strain hypothesis of LFM also applies for CLFM and that the coherency lattice strain responsible for LFM is also the driving force for CLFM.

  16. Thermodynamic watershed hydrological model: Constitutive relationship

    Institute of Scientific and Technical Information of China (English)

    TIAN FuQiang; HU HePing; LEI ZhiDong

    2008-01-01

    The representative elementary watershed (REW) approach proposed by Reggiani et al. Was the first attempt to develop scale adaptable equations applicable directly at the macro scale. Tian et al. Extended the initial definition of REW for simulating the energy related processes, and re-organized the deriving procedure of balance equations so that additional sub-regions and substances could be easily incorpo- rated. The resultant ordinary differential equation set can simulate various hydro- logical processes in a physically reasonable way. However, constitutive and geo- metric relationships have not been developed for Tian et al.'s equation set, which are necessary for the thermodynamic watershed hydrological model to apply in hydrological modeling practice. In this work, the constitutive equations for mass exchange terms and momentum exchange terms were developed as well as geo- metric relationships. The closed ordinary differential equation set with nine equations was finally obtained.

  17. An Elastoplastic Damage Constitutive Model for Concrete

    Institute of Scientific and Technical Information of China (English)

    LIU Jun; LIN Gao; ZHONG Hong

    2013-01-01

    An elastoplastic damage constitutive model to simulate nonlinear behavior of concrete is presented.Similar to traditional plastic theory,the irreversible deformation is modeled in effective stress space.In order to better describe different stiffness degradation mechanisms of concrete under tensile and compressive loading conditions,two damage variables,i.e.,tension and compression are introduced,to quantitatively evaluate the degree of deterioration of concrete structure.The rate dependent behavior is taken into account,and this model is derived firmly in the framework of irreversible thermodynamics.Fully implicit backward-Euler algorithm is suggested to perform constitutive integration.Numerical results of the model accord well with the test results for specimens under uniaxial tension and compression,biaxial loading and triaxial loading.Failure processes of double-edge-notched (DEN) specimen are also simulated to further validate the proposed model.

  18. An elastoplastic damage constitutive model for concrete

    Science.gov (United States)

    Liu, Jun; Lin, Gao; Zhong, Hong

    2013-04-01

    An elastoplastic damage constitutive model to simulate nonlinear behavior of concrete is presented. Similar to traditional plastic theory, the irreversible deformation is modeled in effective stress space. In order to better describe different stiffness degradation mechanisms of concrete under tensile and compressive loading conditions, two damage variables, i.e., tension and compression are introduced, to quantitatively evaluate the degree of deterioration of concrete structure. The rate dependent behavior is taken into account, and this model is derived firmly in the framework of irreversible thermodynamics. Fully implicit backward-Euler algorithm is suggested to perform constitutive integration. Numerical results of the model accord well with the test results for specimens under uniaxial tension and compression, biaxial loading and triaxial loading. Failure processes of double-edge-notched (DEN) specimen are also simulated to further validate the proposed model.

  19. In quest of constitutional principles of "neurolaw".

    Science.gov (United States)

    Pizzetti, Federico Gustavo

    2011-01-01

    The growing use of brain imaging technology and the developing of cognitive neuroscience pose unaccustomed challenges to legal systems. Until now, the fields of Law much affected are the civil and criminal law and procedure, but the constitutional dimension of "neurolaw" cannot be easily underestimated. As the capacity to investigate and to trace brain mechanisms and functional neural activities increases, it becomes urgent the recognition and definition of the unalienable rights and fundamental values in respect of this new techno-scientific power, that must be protected and safeguard at "constitutional level" of norms such as: human dignity, personal identity, authenticity and the pursuit of individual "happiness". As the same as for the law regulating research and experimentation on human genome adopted in the past years, one may also argue if the above mentioned fundamental principles of "neurolaw" must be fixed and disciplined also at European and International level.

  20. Washington upholds HIV exposure law as constitutional.

    Science.gov (United States)

    1999-12-24

    A Washington State appeals court has rejected a constitutional challenge to a law that makes the intentional spreading of HIV to sex partners a crime. The court rejected the notion that the criminal exposure law violated the equal protection clause of the U.S. and State constitutions because it singled out those infected with HIV for unequal treatment. The court saw the law applied specific conduct to all, infected and non-infected alike, not specific groups of people. A second argument that the defendants were denied right of procreation was rejected because those rights are not protected if the defendant intended to inflict bodily injury. In this case, the defendant, [name removed], knowing his HIV status, willingly had sex with several women without warning them of his status or using a condom. The court viewed this behavior as acting with intent to inflict harm. An earlier case involving an HIV-specific criminal exposure law is described.

  1. A constitutional framework for private governance

    OpenAIRE

    2001-01-01

    Regulation is almost a synonym for public law. Government, relying on its sovereign powers, intervenes into freedom for the sake of social betterment. Reality less and less coincides with this traditional picture. Regulation is increasingly replaced by private or hybrid governance, i.e., by blends of private and public elements. Constitutional doctrine is not well prepared for the ensuing four-polar conflict. The four actors are government, the private regulator, its addressees, and the prote...

  2. Constitutive relations for multiphase flow modeling

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, H.; Vaeth, L.; Thurnay, K. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Inst. fuer Neutronenphysik und Reaktortechnik

    1998-01-01

    The constitutive relations that are used in the three-field fluid dynamics code IVA-KA for determining the drag in three-phase mixtures and the heat transferred by radiation are described together with some comparisons of calculational results with experiments. In these experiments (QUEOS), large quantities of solid particles are injected into water. Potential deficiencies of the present drag model are discussed. (author)

  3. Unified viscoplastic constitutive equations and their applications

    Science.gov (United States)

    Lindholm, U. S.

    1987-01-01

    Unified constitutive equations for time- and temperature-dependent metallic plastic deformation have been applied in FEM simulations of forming processes; increasingly powerful computational tools and physical models are being used to numerically model complex engineering problems. Once confidence has been gained through adequate verification, these numerical models will increasingly replace experimental models. Attention is presently given to the contributions made by physical metallurgy, continuum mechanics, and computational mechanics.

  4. Emergency Protocol and Violence Prevention in a University Setting

    Science.gov (United States)

    Rust, Dylan

    2012-01-01

    This study analyzed the emergency protocol and violence prevention methods utilized at an American university. The four research questions were: (1) What are the sources of violence at the university? a. How has the university addressed these sources? (2) What constitutes an emergency in the eyes of the university? (3) How do emergency protocols…

  5. Rapid implementation of advanced constitutive models

    Science.gov (United States)

    Starman, Bojan; Halilovič, Miroslav; Vrh, Marko; Štok, Boris

    2013-12-01

    This paper presents a methodology based on the NICE integration scheme [1, 2] for simple and rapid numerical implementation of a class of plasticity constitutive models. In this regard, an algorithm is purposely developed for the implementation of newly developed advanced constitutive models into explicit finite element framework. The methodology follows the organization of the problem state variables into an extended form, which allows the constitutive models' equations to be organized in such a way, that the algorithm can be optionally extended with minimal effort to integrate also evolution equations related to a description of other specific phenomena, such as damage, distortional hardening, phase transitions, degradation etc. To confirm simplicity of the program implementation, computational robustness, effectiveness and improved accuracy of the implemented integration algorithm, a deep drawing simulation of the cylindrical cup is considered as the case study, performed in ABAQUS/Explicit. As a fairly complex considered model, the YLD2004-18p model [3, 4] is first implemented via external subroutine VUMAT. Further, to give additional proof of the simplicity of the proposed methodology, a combination of the YLD2004-18p model and Gurson-Tvergaard-Needleman model (GTN) is considered. As demonstrated, the implementation is really obtained in a very simple way.

  6. Emerging Powers, Emerging Markets, Emerging Societies

    DEFF Research Database (Denmark)

    Sørensen, Camilla T. N.

    2016-01-01

    How are small states managing the shift under way in the global economic and political order from the United States and Europe towards other regions, especially Asia? In the International Relations literature, there is a tendency to focus on the great powers – they set the scene, and the small...... this in order to analyse the Danish foreign policy reactions to the changing world order and show how the emergence of new powers is gradually affecting Denmark’s foreign policy priorities and its “policy profile....

  7. The European Constitution Project from the Perspective of Constitutional Political Economy

    OpenAIRE

    Feld, Lars P.

    2005-01-01

    Three topics of a European constitution are discussed. First, basic arguments from constitutional political economy that aim at restricting representatives? potential misuse of powers in a European Union with extended competencies are summarized. Since a European demos does not yet exist, an extension of competencies of the Euro¬pean Parliament is not sufficient in order to legitimate political decisions at the EU le¬vel. The introduction of elements of direct democracy in the European cons...

  8. The Embryology and Evolution of Political Constitutions. About some Recent Studies in the English Constitution

    Directory of Open Access Journals (Sweden)

    Luigi Luzzatti

    2013-12-01

    Full Text Available We reedit in the dossier of this issue an essay of Luigi Luzzatti first came out in «Nuova Anthologia» in 1880. In it Luzzatti rereads the British constitutional history thanks to a set of biological metaphors and analogies, which are analyzed and historically framed in the introduction of Luca Ciancio. This approach of Luzzatti further enhances the reconstruction of history of Constitutions he offers analyzing the works of the greatest historians of his time.

  9. Hematologic emergencies

    Directory of Open Access Journals (Sweden)

    Daniele Vallisa

    2012-01-01

    Full Text Available In recent years, the surprising progress made in other areas of hematology (advances in the understanding of leukemogenesis, improved transplant techniques has been conspicuously absent in the management of hematologic emergencies. And yet, every step toward greater knowledge, every new treatment option will be of little value unless we are able to manage the acute complications of hematologic diseases. These complications are better defined as hematologic emergencies, and they are characterized by a high rate of mortality. This review is based on a search of the literature that was initially confined to articles published in the journal Hematology from 2000 to 2009. The search was then extended to the Cochrane Library and to Pub Med in February 2010 with the following Keywords emergencies; urgencies; hematology. The same key words were employed in a search of the archives of Blood and the New England Journal of Medicine from 2000 to 2010. The results confirm that hematologic emergencies can be caused by hematologic malignancies as well as by non-neoplastic hematologic diseases. Within the former category; this review examines the causes; manifestations; treatment and prevention of disseminated intravascular coagulation; superior vena caval syndrome; spinal cord compression; tumor lysis syndrome; hyperleukocytosis; and hypercalcemia. We also review emergency situations associated with non-neoplatic haematological diseases; such as thrombotic thrombocytopenic purpura; drug-induced hemolytic anemia; and acute sickle-cell crisis.

  10. 29 CFR 402.1 - Labor organization constitution and bylaws.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Labor organization constitution and bylaws. 402.1 Section... constitution and bylaws. Every labor organization shall adopt a constitution and bylaws consistent with the... a constitution and bylaws which it has previously adopted and under which it is operating when...

  11. Emergency surgery

    DEFF Research Database (Denmark)

    Stoneham, M; Murray, D; Foss, N

    2014-01-01

    National reports recommended that peri-operative care should be improved for elderly patients undergoing emergency surgery. Postoperative mortality and morbidity rates remain high, and indicate that emergency ruptured aneurysm repair, laparotomy and hip fracture fixation are high-risk procedures...... undertaken on elderly patients with limited physiological reserve. National audits have reported variations in care quality, data that are increasingly being used to drive quality improvement through professional guidance. Given that the number of elderly patients presenting for emergency surgery is likely...... to rise as the population ages, this review summarises the evidence on which such guidance is based, and provides information about how anaesthetists might participate in audit and research aimed at improving local and national outcomes for these most vulnerable of patients....

  12. Emergency preparedness

    CERN Document Server

    Cennini, E; Oortman Gerlings, P

    2009-01-01

    On September 19th 2008, a technical fault was at the centre of a sequence of events which hampered the performance of certain equipments of the LHC 3-4 sector. Once the first effects of this sequence of events were detected, the behaviour of the CERN staff confronted to this complex and critical situation became the centre of the risk control process. During such a downward spiral the preparation of all stakeholders is essential and should respect the (apparently) basic principles of emergency preparedness. Preparedness towards normal operation of CERN facilities towards minor up to major emergency situations will be presented. The main technical, organisational and legal frameworks of the CERN emergency preparedness will be recalled, highlighting the CERN risk management and risk control strategy. Then, the sequence of events experienced by different stakeholders on September 19th will be reported, thus starting the learned lessons process.

  13. Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor

    Directory of Open Access Journals (Sweden)

    Chan Jeannie

    2008-02-01

    revealed conserved residues previously reported for human CES1 involved in catalysis, ligand binding, tertiary structure and organelle localization. Phylogenetic studies indicated the gene duplication events which generated ancestral mammalian CES genes predated the common ancestor for marsupial and eutherian mammals, and appear to coincide with the early diversification of tetrapods.

  14. Updated clusters of orthologous genes for Archaea: a complex ancestor of the Archaea and the byways of horizontal gene transfer

    Directory of Open Access Journals (Sweden)

    Wolf Yuri I

    2012-12-01

    Full Text Available Abstract Background Collections of Clusters of Orthologous Genes (COGs provide indispensable tools for comparative genomic analysis, evolutionary reconstruction and functional annotation of new genomes. Initially, COGs were made for all complete genomes of cellular life forms that were available at the time. However, with the accumulation of thousands of complete genomes, construction of a comprehensive COG set has become extremely computationally demanding and prone to error propagation, necessitating the switch to taxon-specific COG collections. Previously, we reported the collection of COGs for 41 genomes of Archaea (arCOGs. Here we present a major update of the arCOGs and describe evolutionary reconstructions to reveal general trends in the evolution of Archaea. Results The updated version of the arCOG database incorporates 91% of the pangenome of 120 archaea (251,032 protein-coding genes altogether into 10,335 arCOGs. Using this new set of arCOGs, we performed maximum likelihood reconstruction of the genome content of archaeal ancestral forms and gene gain and loss events in archaeal evolution. This reconstruction shows that the last Common Ancestor of the extant Archaea was an organism of greater complexity than most of the extant archaea, probably with over 2,500 protein-coding genes. The subsequent evolution of almost all archaeal lineages was apparently dominated by gene loss resulting in genome streamlining. Overall, in the evolution of Archaea as well as a representative set of bacteria that was similarly analyzed for comparison, gene losses are estimated to outnumber gene gains at least 4 to 1. Analysis of specific patterns of gene gain in Archaea shows that, although some groups, in particular Halobacteria, acquire substantially more genes than others, on the whole, gene exchange between major groups of Archaea appears to be largely random, with no major ‘highways’ of horizontal gene transfer. Conclusions The updated collection

  15. Specific mutations in the HEXA gene among Iraqi Jewish Tay-Sachs disease carriers: dating of founder ancestor.

    Science.gov (United States)

    Karpati, Mazal; Gazit, Ephraim; Goldman, Boleslaw; Frisch, Amos; Colombo, Roberto; Peleg, Leah

    2004-02-01

    The incidence of Tay-Sachs disease (TSD) carriers, as defined by enzyme assay, is 1:29 among Ashkenazi Jews and 1:110 among Moroccan Jews. An elevated carrier frequency of 1:140 was also observed in the Iraqi Jews (IJ), while in other Israeli populations the world's pan-ethnic frequency of approximately 1:280 has been found. Recently a novel mutation, G749T, has been reported in 38.7% of the IJ carriers (24/62). Here we report a second novel HEXA mutation specific to the IJ TDS carriers: a substitution of cytosine 1351 by guanosine (C1351G), resulting in the change of leucine to valine in position 451. This mutation was found in 33.9% (21/62) of the carriers and in none of 100 non-carrier IJ. In addition to the two specific mutations, 14.5% (9/62) of the IJ carriers bear a known "Jewish" mutation (Ashkenazi or Moroccan) and 11.3% (7/62) carry a known "non-Jewish" mutation. In 1 DNA sample no mutation has yet been detected. To investigate the genetic history of the IJ-specific mutations (C1351G and G749T), the allelic distribution of four polymorphic markers (D15S131, D15S1025, D15S981, D15S1050) was analyzed in IJ heterozygotes and ethnically matched controls. Based on linkage disequilibrium, recombination factor (theta) between the markers and mutated loci, and the population growth correction, we deduced that G749T occurred in a founder ancestor 44.8 +/- 14.2 generations (g) ago [95% confidence interval (CI) 17.0-72.6 g] and C1351G arose 80.4 +/- 35.9 g ago (95% CI 44.5-116.3 g). Thus, the estimated dates for introduction of mutations are: 626 +/- 426 A.D. (200-1052 A.D.) for G749T and 442 +/- 1077 B.C. (1519 B.C. to 635 A.D.) for C1351G.

  16. Genetic Approach to Elucidation of Sasang Constitutional Medicine

    OpenAIRE

    Bu-Yeo Kim; Seongwon Cha; Hee-Jeong Jin; Sangkyun Jeong

    2009-01-01

    Sasang Constitutional Medicine (SCM) offers a medical principle that classifies humans into four constitution groups and guides their treatment with constitution-matched medical assistance. The principle of this traditional medicine, although requires significant scientific support, appears to suggest a genetic influence on constitution type. The relative frequency of constitution types in a population, for instance, has remained relatively constant since Jema Lee first described them from hi...

  17. Economic Constitution of Turkey and Three Major Topics

    OpenAIRE

    S. Ridvan Karluk

    2013-01-01

    The most important civil constitution creating process since the establishment of the Republic of Turkey is still ongoing. Economic and financial provisions of our 1982 constitution are not one; in fact they are all over the place. There is an “Economic and Financial Provision” heading under the constitution; however, it is extremely inadequate. The 1982 Constitution is not a constitution in which financial and economic provisions are listed under one section. There has never been an interest...

  18. The Constitutional Deficiencies of the German 'Rechtsgutslehre'

    Directory of Open Access Journals (Sweden)

    Carl-Friedrich Stuckenberg

    2013-01-01

    Full Text Available This paper questions the theoretical merits and constitutional validity of the “Rechtsgutslehre” (doctrine of the protection of legal goods, a widely held doctrine about the limits of legitimate criminalization in Germany and some other jurisdictions. The immediate cause for this reassessment is a recent decision of the German constitutional court which upheld the German incest prohibition and simultaneously rejected the traditional “Rechtsgutslehre” as constitutionally irrelevant, thereby stirring up considerable controversy among academic criminal lawyers. The paper tries to show why the court’s view is correct by pointing out the main deficiencies of the doctrine and what criteria a better theory must fulfil. Este artículo cuestiona los méritos teóricos y la validez constitucional de la "Rechtsgutslehre" (doctrina de la protección de los bienes jurídicos, una doctrina muy extendida acerca de los límites de la criminalización legítima en Alemania y algunas otras jurisdicciones. La causa inmediata de esta nueva valoración es una decisión reciente del Tribunal Constitucional alemán que ratificó la prohibición del incesto en Alemania y al mismo tiempo rechazó el tradicional "Rechtsgutslehre" por ser constitucionalmente irrelevante, lo que provocó una considerable controversia entre la comunidad académica de abogados criminalistas. El artículo trata de mostrar por qué la decisión de la corte es correcta, señalando las deficiencias principales de la doctrina y los criterios que una teoría más adecuada debe cumplir. DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=2200870

  19. Rovac is the possible ancestor of the Russian lapinized vaccines LK-VNIVViM and CS strains but not the Chinese strain (C-strain) vaccine against classical swine fever.

    Science.gov (United States)

    Zhou, Weiguang; Gao, Shandian; Podgórska, Katarzyna; Stadejek, Tomasz; Qiu, Hua-Ji; Yin, Hong; Drew, Trevor; Liu, Lihong

    2014-11-20

    Classical swine fever (CSF), or hog cholera, is a highly contagious disease that emerged in the first half of the nineteenth century. To fight against the disease and protect pigs, different vaccines were developed, including early generation of lapinized Rovac strain and the later development of the “Chinese” strain (C-strain). However, details of the development of these vaccines are lost in history. In order to investigate the phylogenetic relationship between the Rovac and other lapinized vaccines, this study determined the genome sequence of the Rovac, which comprised 12,304 nucleotides, notably with the 3′untranslated region (3′UTR) containing a 13-nucleotide insertion. The near-complete genome of Russian vaccine strain LK-VNIVViM was determined by next-generation sequencing on Illumina MiSeq platform. Whole genome phylogenetic analysis revealed a closer relationship of the Rovac strain with the Russian LK-VNIVViM, CS strain and its derivative RUCSFPLUM (genotype 1.2), rather than with the C-strain (genotype 1.1). In addition, it demonstrated an ancestry role of the LK-VNIVViM in relation to the CS strain and RUCSFPLUM. The study suggested that the Rovac vaccine is the possible ancestor of the Russian vaccine strains but not the C-strain vaccine.

  20. [Constitutive synthesis of cellulase by Trichoderma lignorum].

    Science.gov (United States)

    Lobanok, A G; Pavlovskaia, Zh I

    1977-01-01

    The induction of cellulase synthesis by lactose was studied in the resting cells of Trichoderma lignorum OM 534. The effect depended on the concentration of lactose, pH, and the age of the mycelium. The induction of the enzyme synthesis by lactose is supressed by glucose and its metabolites. The repression by glucose is partly eliminated by Cyk 3'-5'-AMP, theophylline, and coffeine. The induction of cellulase by lactose is regarded as a derepression of the synthesis of this enzyme as a result of slow assimilation of the disaccharide. The synthesis of cellulase in T. lignorum is presumed to be constitutive.

  1. Constitutive modeling for isotropic materials (HOST)

    Science.gov (United States)

    Chan, Kwai S.; Lindholm, Ulric S.; Bodner, S. R.; Hill, Jeff T.; Weber, R. M.; Meyer, T. G.

    1986-01-01

    The results of the third year of work on a program which is part of the NASA Hot Section Technology program (HOST) are presented. The goals of this program are: (1) the development of unified constitutive models for rate dependent isotropic materials; and (2) the demonstration of the use of unified models in structural analyses of hot section components of gas turbine engines. The unified models selected for development and evaluation are those of Bodner-Partom and of Walker. A test procedure was developed for assisting the generation of a data base for the Bodner-Partom model using a relatively small number of specimens. This test procedure involved performing a tensile test at a temperature of interest that involves a succession of strain-rate changes. The results for B1900+Hf indicate that material constants related to hardening and thermal recovery can be obtained on the basis of such a procedure. Strain aging, thermal recovery, and unexpected material variations, however, preluded an accurate determination of the strain-rate sensitivity parameter is this exercise. The effects of casting grain size on the constitutive behavior of B1900+Hf were studied and no particular grain size effect was observed. A systematic procedure was also developed for determining the material constants in the Bodner-Partom model. Both the new test procedure and the method for determining material constants were applied to the alternate material, Mar-M247 . Test data including tensile, creep, cyclic and nonproportional biaxial (tension/torsion) loading were collected. Good correlations were obtained between the Bodner-Partom model and experiments. A literature survey was conducted to assess the effects of thermal history on the constitutive behavior of metals. Thermal history effects are expected to be present at temperature regimes where strain aging and change of microstructure are important. Possible modifications to the Bodner-Partom model to account for these effects are outlined

  2. Numerically abnormal chromosome constitutions in humans

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-12-31

    Chapter 24, discusses numerically abnormal chromosome constitutions in humans. This involves abnormalities of human chromosome number, including polyploidy (when the number of sets of chromosomes increases) and aneuploidy (when the number of individual normal chromosomes changes). Chapter sections discuss the following chromosomal abnormalities: human triploids, imprinting and uniparental disomy, human tetraploids, hydatidiform moles, anomalies caused by chromosomal imbalance, 13 trisomy (D{sub 1} trisomy, Patau syndrome), 21 trisomy (Down syndrome), 18 trisomy syndrome (Edwards syndrome), other autosomal aneuploidy syndromes, and spontaneous abortions. The chapter concludes with remarks on the nonrandom participation of chromosomes in trisomy. 69 refs., 3 figs., 4 tabs.

  3. Thyroid emergencies.

    Science.gov (United States)

    Klubo-Gwiezdzinska, Joanna; Wartofsky, Leonard

    2012-03-01

    This review presents current knowledge about the thyroid emergencies known as myxedema coma and thyrotoxic storm. Understanding the pathogenesis of these conditions, appropriate recognition of the clinical signs and symptoms, and their prompt and accurate diagnosis and treatment are crucial in optimizing survival.

  4. Emergency Preparedness

    CERN Document Server

    2001-01-01

    The trends of RPC work in the area of preparedness for nuclear and radiological accidents are listed. RPC in cooperation with Swedish Government developed the project on preparation for iodine prophylaxis in case of accident at Ignalina NPP and arranged seminar on emergency preparedness issues in 2001.

  5. Studying Emerge

    DEFF Research Database (Denmark)

    Davies, Sarah Rachael; Selin, Cynthia; Rodegher, Sandra

    2015-01-01

    The Emerge event, held in Tempe, AZ in March 2012, brought together a range of scientists, artists, futurists, engineers and students in order to experiment with innovative methods for thinking about the future. These methodological techniques were tested through nine workshops, each of which made...

  6. Emerging Materiality

    DEFF Research Database (Denmark)

    Bertelsen, Olav Wedege; Breinbjerg, Morten; Pold, Søren

    2009-01-01

    The authors examine how materiality emerges from complex chains of mediation in creative software use. The primarily theoretical argument is inspired and illustrated by interviews with two composers of electronic music. The authors argue that computer mediated activity should not primarily...

  7. Emergence delirium

    DEFF Research Database (Denmark)

    Munk, Louise; Andersen, Lars Peter Holst; Gögenur, Ismail

    2013-01-01

    Emergence delirium (ED) is a well-known phenomenon in the postoperative period. However, the literature concerning this clinical problem is limited. This review evaluates the literature with respect to epidemiology and risk factors. Treatment strategies are discussed. The review concludes...

  8. Postmodern Emergence

    Science.gov (United States)

    Somerville, Margaret

    2007-01-01

    This paper is a work-in-progress in which the author will begin to articulate the elements of a new methodology that she is calling, for the moment, a methodology of postmodern emergence. She explores this approach through examples from her own research journals that follow her research-in-process and from observing student work-in-progress. She…

  9. Who Is Afraid of European Constitutionalism?

    DEFF Research Database (Denmark)

    Wind, Marlene

    2014-01-01

    Abstract: According to Ronald Dworkin, majoritarian democracies like the Nordic ones are founded upon the notion that parliamentary majorities are elevated above the other branches of government and that such majorities should not be subject to judicial review. The emergence of a powerful...

  10. Constitutive modeling of contact angle hysteresis.

    Science.gov (United States)

    Vedantam, Srikanth; Panchagnula, Mahesh V

    2008-05-15

    We introduce a phase field model of wetting of surfaces by sessile drops. The theory uses a two-dimensional non-conserved phase field variable to parametrize the Gibbs free energy of the three-dimensional system. Contact line tension and contact angle hysteresis arise from the gradient term in the free energy and the kinetic coefficient respectively. A significant advantage of this approach is in the constitutive specification of hysteresis. The advancing and receding angles of a surface, the liquid-vapor interfacial energy and three-phase line tension are the only required constitutive inputs to the model. We first simulate hysteresis on a smooth chemically homogeneous surface using this theory. Next we show that it is possible to study heterogeneous surfaces whose component surfaces are themselves hysteretic. We use this theory to examine the wetting of a surface containing a circular heterogeneous island. The contact angle for this case is found to be determined solely by the material properties at the contact line in accord with recent experimental data.

  11. Constitutive equations for an electroactive polymer

    Science.gov (United States)

    Tixier, Mireille; Pouget, Joël

    2016-07-01

    Ionic electroactive polymers can be used as sensors or actuators. For this purpose, a thin film of polyelectrolyte is saturated with a solvent and sandwiched between two platinum electrodes. The solvent causes a complete dissociation of the polymer and the release of small cations. The application of an electric field across the thickness results in the bending of the strip and vice versa. The material is modeled by a two-phase continuous medium. The solid phase, constituted by the polymer backbone inlaid with anions, is depicted as a deformable porous media. The liquid phase is composed of the free cations and the solvent (usually water). We used a coarse grain model. The conservation laws of this system have been established in a previous work. The entropy balance law and the thermodynamic relations are first written for each phase and then for the complete material using a statistical average technique and the material derivative concept. One deduces the entropy production. Identifying generalized forces and fluxes provides the constitutive equations of the whole system: the stress-strain relations which satisfy a Kelvin-Voigt model, generalized Fourier's and Darcy's laws and the Nernst-Planck equation.

  12. The Eurozone Crisis: A Constitutional Analysis

    Directory of Open Access Journals (Sweden)

    Anna Sting

    2015-08-01

    Full Text Available “Every power comes through crisis” has long been a motif of European integration. The financial and sovereign debt crises, which have shaken the European Union (EU in recent years, are at first glance no different. Treaty reforms, intergovernmental treaties such as the Fiscal Compact and the Treaty Establishing a European Stability Mechanism (ESM Treaty have significantly altered the constitutional landscape of the EU and its Member States. The crisis has also inspired many European legal scholars to critically analyse the EU’s system of economic governance, as have other events throughout the history of the European Union, from the Empty Chair Crisis to the referenda in the aftermath of the Treaty of Maastricht and the failure of the Constitution for the European Union. What does seem to be different is the way in which scholars approach the issue of the Eurozone crisis. Instead of a purely legal perspective on economic governance, European legal scholars have realised that in order to understand and analyse the euro crisis, interdisciplinarity is the word of the moment.

  13. Constitutional moments in governing science and technology.

    Science.gov (United States)

    Jasanoff, Sheila

    2011-12-01

    Scholars in science and technology studies (STS) have recently been called upon to advise governments on the design of procedures for public engagement. Any such instrumental function should be carried out consistently with STS's interpretive and normative obligations as a social science discipline. This article illustrates how such threefold integration can be achieved by reviewing current US participatory politics against a 70-year backdrop of tacit constitutional developments in governing science and technology. Two broad cycles of constitutional adjustment are discerned: the first enlarging the scope of state action as well as public participation, with liberalized rules of access and sympathetic judicial review; the second cutting back on the role of the state, fostering the rise of an academic-industrial complex for technology transfer, and privatizing value debates through increasing delegation to professional ethicists. New rules for public engagement in the United Sates should take account of these historical developments and seek to counteract some of the anti-democratic tendencies observable in recent decades.

  14. HOW STAR WARS ILLUMINATES CONSTITUTIONAL LAW

    Directory of Open Access Journals (Sweden)

    Cass R. Sunstein

    2017-02-01

    Full Text Available Human beings often see coherence and planned design when neither exists. This is so in movies, literature, history, economics, and psychoanalysis – and constitutional law. Contrary to the repeated claims of George Lucas, its principal author, the Star Wars series was hardly planned in advance; it involved a great deal of improvisation and surprise, even to Lucas himself. Serendipity and happenstance, sometimes in the forms of eruptions of new thinking, play a pervasive and overlooked role in the creative imagination, certainly in single authored works, and even more in multi-authored ones extending over time. Serendipity imposes serious demands on the search for coherence in art, literature, history, and law. That search leads many people (including Lucas to misdescribe the nature of their own creativity and authorship. The misdescription appears to respond to a serious human need for sense-making and pattern-finding, but it is a significant obstacle to understanding and critical reflection. Whether Jedi or Sith, many authors of constitutional law are a lot like the author of Star Wars, disguising the essential nature of their own creative processes.

  15. Post-Revolution Constitutionalism: The Impact of Drafting Processes on the Constitutional Documents in Tunisia and Egypt

    DEFF Research Database (Denmark)

    Elsayed, Ahmed Mohamed Abdelfattah

    2014-01-01

    This paper seeks to address the constitutional paths that followed the Arab awakening in both Tunisia and Egypt. The Tunisian constitutional process, despite some tensions, was largely peaceful and consensual. On the other hand, the process in Egypt of establishing a new constitutional arrangement...... at identifying the factors have impacted both the constitutional drafting process and the popular perception of the produced constitutions in each of Tunisia and Egypt....

  16. The Constitutional Court and the Imperative of its Reform

    Directory of Open Access Journals (Sweden)

    Claudia Gilia

    2012-12-01

    Full Text Available Recent debates on the upcoming review of the Constitution have determined us to pay close attention to the basic institution in a democratic state, that is the Constitutional Court. Being caught in the crossfire between power and opposition, the Constitutional Court had a hard time lately, facing severe attacks. The aim of our study is to analyze the evolution of the Constitutional Court within the inland constitutional system, particularly bringing up the flaws describing the Court’s activity. We have also analyzed the proposals put forth by several bodies or experts regarding the constitutional contentious court. At the end of our study, following an analysis of different constitutional types of constitutional review, used by a number of states in Europe, we introduced several resolutions that may improve the role, the course and, last but not least, the activity of the Romanian Constitutional Court.

  17. Emergency Contraception

    Directory of Open Access Journals (Sweden)

    Gemzell-Danielsson K

    2010-01-01

    Full Text Available There have been numerous attempts to control fertility after unprotected sexual intercourse. From very bizarre methods like the vaginal application of Coca Cola to the more serious attempts using calcium antagonists influencing fertility parameters in sperm to hormonal methods or intrauterine devices. So far, hormonal methods preventing or delaying ovulation have proved to be the most popular starting with the combination of ethinyl estradiol and levonorgestrel, known as the Yuzpe regimen. The first dose had to be taken within 72 hours of unprotected intercourse, a second one 12 hours later. Later on, levonorgestrel alone, at first in a regimen similar to the Yuzpe method (2 × 0.75 mg 12 hours apart showed to be more successful, eventually resulting in the development of a 1.5 mg levonorgestrel pill that combined good efficacy with a high ease of use. It has become the standard method used up to this day in most countries. Since the mid 1970s copper IUDs have been used for emergency contraception, which show a high efficacy. Their disadvantages lie in the fact that emergency contraception is considered an off label use and that they might not be acceptable for every patient. Mifepristone in doses of 10 or 25 mg is being used successfully as an emergency contraceptive in China, but has never received any significant consideration in Western countries. The most recent development is the approval of the selective progesterone receptor modulator ulipristal acetate in the dosage of 30 mg for emergency contraception up to 5 days after unprotected intercourse, combining the safe and easy application of the single dose levonorgestrel pill with an even higher efficacy. Several efficacious and easy to use methods for emergency contraception are available on the market today with the most widely spread being levonorgestrel in a single dose of 1.5 mg (given as one tablet of 1.5 mg or 2 tablets of 0.75 mg each for administration up to 3 days after

  18. Emerging Multinationals

    DEFF Research Database (Denmark)

    Gammeltoft, Peter

    ) and books (e.g. Goldstein 2007; Benito and Narula 2007). This paper takes stock of the mounting trend of outward FDI from emerging economies, with special focus on a group of five countries, which are becoming increasingly economically and politically influential, viz. the ‘BRICS' countries. An ‘S......' is appended here to the conventional acronym of ‘BRIC' (Brazil, Russia, India, China) to include the largest economy on the African continent, South Africa. The five BRICS countries produced some USD25 billion of outward FDI flows in 2004, corresponding to some 3 percent of world FDI flows and well over half...... (61 percent) of total developing country outflows. OFDI from the BRICS countries has grown rapidly over the last few years, while still remaining modest compared to many developed countries. Following a brief discussion of FDI and emerging economies in general the article proceeds to hypothesise...

  19. Global Constitutionalism, Control of Conventionality and the Right to Strike in Chile

    Directory of Open Access Journals (Sweden)

    Gonzalo Aguilar Cavallo

    2016-01-01

    Full Text Available n the Inter-American context, the control of conventionality promoted by the Inter-American Court of Human Rights is linked to the process of construction of an ius commune in human rights. Human rights are identified as norm of constitutional character. The universality of human rights allows its consideration as an aspect of global constitutionalism. This paper aims at determining whether the control of conventionality can be considered an expression of global constitutionalism within the Inter-American region. We hold that the control of conventionality in the Inter-American system has propelled the application of a minimum standard of human rights and has stimulated the emergence of an ius commune in human rights.

  20. Emerging Technologies

    OpenAIRE

    Salgar, S. M.

    2004-01-01

    Phenomenal advancements have taken place in the field of Information and communication technologies in the last decade. Spectacular and innovative changes are expected to take place in these fields in coming decade. Networking technologies are going through a sea change. This paper enumerates the likely networking technologies which are emerging, particularly WLANs. Most of the personal communication in the country will be through cellular/ mobile technologies, which are also covered in the p...

  1. Emerging and re-emerging bacterial diseases in India

    Indian Academy of Sciences (India)

    T D Chugh

    2008-11-01

    There has been a remarkable progress in the prevention, control and even eradication of infectious diseases with improved hygiene and development of antimicrobials and vaccines. However, infectious diseases still remain a leading cause of global disease burden with high morbidity and mortality especially in the developing world. Furthermore, there have been threats of new diseases during the past three decades due to the evolution and adaptation of microbes and the re-emergence of old diseases due to the development of antimicrobial resistance and the capacity to spread to new geographic areas. The impact of the emerging and re-emerging diseases in India has been tremendous at socioeconomic and public health levels. Their control requires continuing surveillance, research and training, better diagnostic facilities and improved public health system. Emerging and reemerging zoonotic diseases, foodborne and waterborne diseases and diseases caused by multiresistant organisms constitute the major threats in India. This review of bacterial emerging and re-emerging diseases should be of critical importance to microbiologists, clinicians, public health personnel and policy makers in India.

  2. Emerging jets

    Energy Technology Data Exchange (ETDEWEB)

    Schwaller, Pedro; Stolarski, Daniel [European Organization for Nuclear Research (CERN), Geneva (Switzerland). TH-PH Div.; Weiler, Andreas [European Organization for Nuclear Research (CERN), Geneva (Switzerland). TH-PH Div.; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2015-02-15

    In this work, we propose a novel search strategy for new physics at the LHC that utilizes calorimeter jets that (i) are composed dominantly of displaced tracks and (ii) have many different vertices within the jet cone. Such emerging jet signatures are smoking guns for models with a composite dark sector where a parton shower in the dark sector is followed by displaced decays of dark pions back to SM jets. No current LHC searches are sensitive to this type of phenomenology. We perform a detailed simulation for a benchmark signal with two regular and two emerging jets, and present and implement strategies to suppress QCD backgrounds by up to six orders of magnitude. At the 14 TeV LHC, this signature can be probed with mediator masses as large as 1.5 TeV for a range of dark pion lifetimes, and the reach is increased further at the high-luminosity LHC. The emerging jet search is also sensitive to a broad class of long-lived phenomena, and we show this for a supersymmetric model with R-parity violation. Possibilities for discovery at LHCb are also discussed.

  3. [Constitutions and generalities in traditional Tibetan medicine].

    Science.gov (United States)

    Rovere, P M

    1986-04-28

    The present work is the result of a preliminary study promoted by C.I.S.ME.T. (the International Tibetan Medicine Study Centre) and aims to unify the diagnostic and therapeutic language of various medical cultures. In line with the spirit of the W.H.O. aimed at safeguarding the cultural heritage represented by popular and traditional medicine, encouraged by the Tibetan Medical Centre and under the auspices of His Holiness the Dalai Lama a terminological and conceptual integration of the basic elements of traditional Tibetan medicine is proposed. The Rlung, Bad Kan, Mkris Pa constitution is correlated with embryological anatomy. The 5 exhalations, 5 biles and 5 phlegbs are analysed from a tissue viewpoint with a search for parallels with embryological tissues.

  4. Constitutive model with time-dependent deformations

    DEFF Research Database (Denmark)

    Krogsbøll, Anette

    1998-01-01

    are common in time as well as size. This problem is adressed by means of a new constitutive model for soils. It is able to describe the behavior of soils at different deformation rates. The model defines time-dependent and stress-related deformations separately. They are related to each other and they occur......In many geological and Engineering problems it is necessary to transform information from one scale to another. Data collected at laboratory scale are often used to evaluate field problems on a much larger scale. This is certainly true for geological problems where extreme scale differences...... simultanelously. The model is based on concepts from elasticity and viscoplasticity theories. In addition to Hooke's law for the elastic behavior, the framework for the viscoplastic behavior consists, in the general case (two-dimensional or three-dimensional), of a yield surface, an associated flow rule...

  5. Constitutive Models for Shape Memory Alloy Polycrystals

    Science.gov (United States)

    Comstock, R. J., Jr.; Somerday, M.; Wert, J. A.

    1996-01-01

    Shape memory alloys (SMA) exhibiting the superelastic or one-way effects can produce large recoverable strains upon application of a stress. In single crystals this stress and resulting strain are very orientation dependent. We show experimental stress/strain curves for a Ni-Al single crystal for various loading orientations. Also shown are model predictions; the open and closed circles indicate recoverable strains obtained at various stages in the transformation process. Because of the strong orientation dependence of shape memory properties, crystallographic texture can be expected to play an important role in the mechanical behavior of polycrystalline SMA. It is desirable to formulate a constitutive model to better understand and exploit the unique properties of SMA.

  6. 论宪法%On the Constitution

    Institute of Scientific and Technical Information of China (English)

    Mortimer J.Adler; 邓正来

    2006-01-01

    下述三个问题之间有着极其紧密的关系,所以我们必须把它们放在一起加以讨论:第一,将宪法(constitution)视作建立和组织一个政治共同体(a political community)的观点;第二,视宪政(constitutionality)原则为确定各种政体之一般形式的努力;以及第三,立宪政府(constitutional government)的性质。在本章中,我们用“宪法”一词来表达一种根本的观念,而本章所考虑的所有其他问题都由此一观念衍生而来。

  7. Understanding Legal Evolution Through Constitutional Theory: The Concept of Constitutional (In-)Flexibility

    NARCIS (Netherlands)

    E. Mak (Elaine)

    2012-01-01

    markdownabstract__Abstract__ Why do legal arrangements for the institutions of government (legislative, executive, judicial branches) in Western liberal democracies develop faster, or in a different way, in one jurisdiction in comparison to another? In this article, it is argued that constitutional

  8. South Africa: constitutional court rejects constitutional challenge to law criminalizing prostitution.

    Science.gov (United States)

    Nelson, John

    2003-04-01

    On 9 October 2002, a majority of South Africa's Constitutional Court dismissed appeals from convictions for prostitution and keeping a brothel, rejecting arguments that the law was unconstitutional. However, the minority decision, endorsed by five of eleven judges, found that the provision that made the sex worker but not the client guilty of a criminal offence was discriminatory and should be struck down.

  9. Pinning down the Constitution: Interactively Teaching Congress's Power, Federalism, and Constitutional Interpretation

    Science.gov (United States)

    Emenaker, Ryan

    2014-01-01

    "Pin-the-Tail-on-the-Constitution" is an engaged-learning activity that has been conducted in 26 classes over the past four years. The activity teaches multiple themes commonly included in a variety of courses on American politics such as federalism, congressional powers, the role of the federal courts, and the relevance of the commerce…

  10. Respond to Emergency, Safeguard Constitutional Rights and Restrain Public Power More Effectively by Reform and Innovation- Taking the Rescue Lessons of Yong - Wen Line Bullet Train Rear- End Accident as a Study Clue%通过改革创新更有效地应对突发事件、保障基本权利、约束公共权力——以甬温线动车追尾事故救援处置工作教训为研究线索

    Institute of Scientific and Technical Information of China (English)

    莫于川

    2012-01-01

    Yong -wen Line accident has warned that the malpractice of integration of government administration with enterprise should be rectified in railway system. Meanwhile, it has revealed many problems existing in the legal construction of emergency in in railway system. However, to slolve those problems should enhance both the hardware and sofeware construction by reform and innovation of legal system to more effectively respond to emergency, safeguard constitutional rights and restrain public power.%甬温线特大事故警示人们,必须坚决纠正铁路系统政企不分的弊端;甬温线特大事故充分暴露出铁路系统应急法制建设的诸多问题和矛盾,应当予以分析解决;不但应从加强“硬件建设”的角度,还应从加强“软件建设”的角度,配套采取体制、机制和法制改革创新举措,依法有效地应对突发事件、保障基本权利、约束公共权力,提高铁路系统的危机管理和应急法制水平。

  11. Is it an Emergency?

    Science.gov (United States)

    ... Emergency 101 Share this! Home » Emergency 101 Is it an Emergency? Medical emergencies can be frightening and ... situation. Here you can find information about emergencies. It is essential to know how to recognize the ...

  12. On Eulerian constitutive equations for modeling growth and residual stresses in arteries.

    Science.gov (United States)

    Volokh, K Y

    2005-06-01

    Recently Volokh and Lev (2005) argued that residual stresses could appear in growing arteries because of the arterial anisotropy. This conclusion emerged from a continuum mechanics theory of growth of soft biological tissues proposed by the authors. This theory included Lagrangian constitutive equations, which were formulated directly with respect to the reference configuration. Alternatively, it is possible to formulate Eulerian constitutive equations with respect to the current configuration and to 'pull them back' to the reference configuration. Such possibility is examined in the present work. The Eulerian formulation of the constitutive equations is used for a study of arterial growth. It is shown, particularly, that bending resultants are developed in the ring cross-section of the artery. These resultants may cause the ring opening or closing after cutting the artery in vitro as it is observed in experiments. It is remarkable that the results of the present study, based on the Eulerian constitutive equations, are very similar to the results of Volokh and Lev (2005), based on the Lagrangian constitutive equations. This strengthens the authors' argument that anisotropy is a possible reason for accumulation of residual stresses in arteries. This argument appears to be invariant with respect to the mathematical description.

  13. Sequence Evolution and Expression of the Androgen Receptor and Other Pathway-Related Genes in a Unisexual Fish, the Amazon Molly, Poecilia formosa, and Its Bisexual Ancestors.

    Directory of Open Access Journals (Sweden)

    Fangjun Zhu

    Full Text Available The all-female Amazon molly (Poecilia formosa originated from a single hybridization of two bisexual ancestors, Atlantic molly (Poecilia mexicana and sailfin molly (Poecilia latipinna. As a gynogenetic species, the Amazon molly needs to copulate with a heterospecific male, but the genetic information of the sperm-donor does not contribute to the next generation, as the sperm only acts as the trigger for the diploid eggs' embryogenesis. Here, we study the sequence evolution and gene expression of the duplicated genes coding for androgen receptors (ars and other pathway-related genes, i.e., the estrogen receptors (ers and cytochrome P450, family19, subfamily A, aromatase genes (cyp19as, in the Amazon molly, in comparison to its bisexual ancestors. Mollies possess-as most other teleost fish-two copies of the ar, er, and cyp19a genes, i.e., arα/arβ, erα/erβ1, and cyp19a1 (also referred as cyp19a1a/cyp19a2 (also referred to as cyp19a1b, respectively. Non-synonymous single nucleotide polymorphisms (SNPs among the ancestral bisexual species were generally predicted not to alter protein function. Some derived substitutions in the P. mexicana and one in P. formosa are predicted to impact protein function. We also describe the gene expression pattern of the ars and pathway-related genes in various tissues (i.e., brain, gill, and ovary and provide SNP markers for allele specific expression research. As a general tendency, the levels of gene expression were lowest in gill and highest in ovarian tissues, while expression levels in the brain were intermediate in most cases. Expression levels in P. formosa were conserved where expression did not differ between the two bisexual ancestors. In those cases where gene expression levels significantly differed between the bisexual species, P. formosa expression was always comparable to the higher expression level among the two ancestors. Interestingly, erβ1 was expressed neither in brain nor in gill in the

  14. The ancestor of the Paulinella chromatophore obtained a carboxysomal operon by horizontal gene transfer from a Nitrococcus-like γ-proteobacterium

    Directory of Open Access Journals (Sweden)

    Glöckner Gernot

    2007-06-01

    Full Text Available Abstract Background Paulinella chromatophora is a freshwater filose amoeba with photosynthetic endosymbionts (chromatophores of cyanobacterial origin that are closely related to free-living Prochlorococcus and Synechococcus species (PS-clade. Members of the PS-clade of cyanobacteria contain a proteobacterial form 1A RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase that was acquired by horizontal gene transfer (HGT of a carboxysomal operon. In rDNA-phylogenies, the Paulinella chromatophore diverged basal to the PS-clade, raising the question whether the HGT occurred before or after the split of the chromatophore ancestor. Results Phylogenetic analyses of the almost complete rDNA operon with an improved taxon sampling containing most known cyanobacterial lineages recovered the Paulinella chromatophore as sister to the complete PS-clade. The sequence of the complete carboxysomal operon of Paulinella was determined. Analysis of RubisCO large subunit (rbcL sequences revealed that Paulinella shares the proteobacterial form 1A RubisCO with the PS-clade. The γ-proteobacterium Nitrococcus mobilis was identified as sister of the Paulinella chromatophore and the PS-clade in the RubisCO phylogeny. Gene content and order in the carboxysomal operon correlates well with the RubisCO phylogeny demonstrating that the complete carboxysomal operon was acquired by the common ancestor of the Paulinella chromatophore and the PS-clade through HGT. The carboxysomal operon shows a significantly elevated AT content in Paulinella, which in the rbcL gene is confined to third codon positions. Combined phylogenies using rbcL and the rDNA-operon resulted in a nearly fully resolved tree of the PS-clade. Conclusion The HGT of the carboxysomal operon predated the divergence of the chromatophore ancestor from the PS-clade. Following HGT and divergence of the chromatophore ancestor, diversification of the PS-clade into at least three subclades occurred. The

  15. Sequence Evolution and Expression of the Androgen Receptor and Other Pathway-Related Genes in a Unisexual Fish, the Amazon Molly, Poecilia formosa, and Its Bisexual Ancestors

    Science.gov (United States)

    Zhu, Fangjun; Schlupp, Ingo; Tiedemann, Ralph

    2016-01-01

    The all-female Amazon molly (Poecilia formosa) originated from a single hybridization of two bisexual ancestors, Atlantic molly (Poecilia mexicana) and sailfin molly (Poecilia latipinna). As a gynogenetic species, the Amazon molly needs to copulate with a heterospecific male, but the genetic information of the sperm-donor does not contribute to the next generation, as the sperm only acts as the trigger for the diploid eggs’ embryogenesis. Here, we study the sequence evolution and gene expression of the duplicated genes coding for androgen receptors (ars) and other pathway-related genes, i.e., the estrogen receptors (ers) and cytochrome P450, family19, subfamily A, aromatase genes (cyp19as), in the Amazon molly, in comparison to its bisexual ancestors. Mollies possess–as most other teleost fish—two copies of the ar, er, and cyp19a genes, i.e., arα/arβ, erα/erβ1, and cyp19a1 (also referred as cyp19a1a)/cyp19a2 (also referred to as cyp19a1b), respectively. Non-synonymous single nucleotide polymorphisms (SNPs) among the ancestral bisexual species were generally predicted not to alter protein function. Some derived substitutions in the P. mexicana and one in P. formosa are predicted to impact protein function. We also describe the gene expression pattern of the ars and pathway-related genes in various tissues (i.e., brain, gill, and ovary) and provide SNP markers for allele specific expression research. As a general tendency, the levels of gene expression were lowest in gill and highest in ovarian tissues, while expression levels in the brain were intermediate in most cases. Expression levels in P. formosa were conserved where expression did not differ between the two bisexual ancestors. In those cases where gene expression levels significantly differed between the bisexual species, P. formosa expression was always comparable to the higher expression level among the two ancestors. Interestingly, erβ1 was expressed neither in brain nor in gill in the analyzed

  16. The Separation of Church and State. Exploring the Constitution Series.

    Science.gov (United States)

    McWhirter, Darien A.

    This textbook on the separation of church and state continues the "Exploring the Constitution Series," which introduces important areas of constitutional law. Intended to serve either as a reference work, a supplement to a standard textbook, or as the textbook for a course, this volume covers the constitutional issues of prayer in public…

  17. 43 CFR 1.5 - Signature to constitute certificate.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Signature to constitute certificate. 1.5... OF THE INTERIOR § 1.5 Signature to constitute certificate. When an individual who appears in a representative capacity signs a paper in practice before the Department, his signature shall constitute...

  18. 29 CFR 452.109 - Constitution of labor organization.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Constitution of labor organization. 452.109 Section 452.109... AND DISCLOSURE ACT OF 1959 Election Procedures; Rights of Members § 452.109 Constitution of labor organization. Elections must be conducted in accordance with the constitution and bylaws of the...

  19. Frederick Douglass Changed My Mind about the Constitution

    Science.gov (United States)

    Oakes, James

    2008-01-01

    Frederick Douglass dramatically and publicly changed his own mind about the Constitution. Like Frederick Douglass, the author had originally viewed the Constitution as pro-slavery. Yet a close look at Douglass's writings revealed a Constitution that empowered the federal government to abolish slavery.

  20. 29 CFR 452.3 - Interpretations of constitution and bylaws.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Interpretations of constitution and bylaws. 452.3 Section... REPORTING AND DISCLOSURE ACT OF 1959 General Considerations § 452.3 Interpretations of constitution and bylaws. The interpretation consistently placed on a union's constitution by the responsible...

  1. Constitution Day: Start the School Year with Civics

    Science.gov (United States)

    Lesser, Eli J.

    2006-01-01

    The celebration and recognition of Constitution Day on September 17th is now required by federal law. The new law, known colloquially as the Byrd Amendment, requires all schools receiving any federal assistance, from kindergarten to higher education, to teach students about the Constitution on Constitution Day. The concept of a school's civic…

  2. Constitutive Theory Developed for Monolithic Ceramic Materials

    Science.gov (United States)

    Janosik, Lesley A.

    1998-01-01

    With the increasing use of advanced ceramic materials in high-temperature structural applications such as advanced heat engine components, the need arises to accurately predict thermomechanical behavior that is inherently time-dependent and that is hereditary in the sense that the current behavior depends not only on current conditions but also on the material's thermomechanical history. Most current analytical life prediction methods for both subcritical crack growth and creep models use elastic stress fields to predict the time-dependent reliability response of components subjected to elevated service temperatures. Inelastic response at high temperatures has been well documented in the materials science literature for these material systems, but this issue has been ignored by the engineering design community. From a design engineer's perspective, it is imperative to emphasize that accurate predictions of time-dependent reliability demand accurate stress field information. Ceramic materials exhibit different time-dependent behavior in tension and compression. Thus, inelastic deformation models for ceramics must be constructed in a fashion that admits both sensitivity to hydrostatic stress and differing behavior in tension and compression. A number of constitutive theories for materials that exhibit sensitivity to the hydrostatic component of stress have been proposed that characterize deformation using time-independent classical plasticity as a foundation. However, none of these theories allow different behavior in tension and compression. In addition, these theories are somewhat lacking in that they are unable to capture the creep, relaxation, and rate-sensitive phenomena exhibited by ceramic materials at high temperatures. The objective of this effort at the NASA Lewis Research Center has been to formulate a macroscopic continuum theory that captures these time-dependent phenomena. Specifically, the effort has focused on inelastic deformation behavior associated

  3. Financial Accounting Constitution or its Referential Matrix

    Directory of Open Access Journals (Sweden)

    Niculae Feleaga

    2006-07-01

    Full Text Available Using a simplified approach it may be stated that the financial accounting theoretical framework is structured on three levels. At the first level, reference is made to the accounting objectives. These objectives are fundamental for the theoretical framework. At the second level, we find the accounting information characteristics and explicit mentions about the headings of financial statements. The mentioned characteristics of accounting information represent the basic issues for ensuring its utility. The headings represent the main categories of elements disclosed in the financial statements, like assets and liabilities – these two elements’ definitions brought radical changes both in the accounting thinking and practices. Overall, the second level’s components represent the basis for building the practice directives as a matter of recognition (identification and measurement (evaluation. Inside the third level, the recognition and measurement directives are being detailed, which will be further used by the accounting specialist in order to identify and apply the accounting standards. These two directives enclose postulates, principles and restrictions. Such specifications prove to be useful whenever precise answers must be given to relative financial information issues. Usually, it is accepted that the theoretical framework, also called the accounting framework is the standard-setting, metaphorically speaking is actually the constitution of financial accounting, or in other words, its reference matrix.

  4. A constitutive equation for stratospheric balloon materials

    Science.gov (United States)

    Rand, J.; Sterling, J.

    The selection of a suitable material for use as a reliable stratospheric balloon gas barrier and structural component is based on a variety of desired properties. In order to achieve the required combination of weight per unit area, helium permeation, strength, flexibility and toughness at low temperatures, low density polyethylene has been used for the last half century. During the last decade, linear low density polyethylene (LLDPE) has been found to have even better properties for this application. Thin films extruded from this type resin have been found to have time dependent properties which should be understood in order to make an intelligent analysis of the balloon. This paper describes the current effort to characterize a 38 micron coextrusion of LLDPE as a nonlinearly viscoelastic material. The resulting constitutive equation may be used to accurately describe the time dependent creep and/or relaxation of this film when subjected to a biaxial state of stress. Recent laboratory data have been used to modify an existing model of LLDPE to account for differences caused by the coextrusion process. The new model will facilitate structure design optimization and reliability assessment, and may further be utilized as a predictive tool to benefit in-flight operations. Unfortunately, current structural analysis techniques based on linear elastic properties will predict stresses in excess of those which actually exist. An example will be presented which demonstrates the magnitude of this error when nonlinear behavior is ignored.

  5. A nonlinear constitutive model for magnetostrictive materials

    Institute of Scientific and Technical Information of China (English)

    Xin'en Liu; Xiaojing Zheng

    2005-01-01

    A general nonlinear constitutive model is proposed for magnetostrictive materials, based on the important physical fact that a nonlinear part of the elastic strain produced by a pre-stress is related to the magnetic domain rotation or movement and is responsible for the change of the maximum magnetostrictive strain with the pre-stress. To avoid the complicity of determining the tensor function describing the nonlinear elastic strain part, this paper proposes a simplified model by means of linearizing the nonlinear function.For the convenience of engineering applications, the expressions of the 3-D (bulk), 2-D (film) and 1-D (rod) models are, respectively, given for an isotropic material and their applicable ranges are also discussed. By comparison with the experimental data of a Terfenol-D rod, it is found that the proposed model can accurately predict the magnetostrictive strain curves in low, moderate and high magnetic field regions for various compressive pre-stress levels. The numerical simulation further illustrates that, for either magnetostrictive rods or thin films, the proposed model can effectively describe the effects of the pre-stress or residual stress on the magnetization and magnetostrictive strain curves, while none of the known models can capture all of them. Therefore, the proposed model enjoys higher precision and wider applicability than the previous models, especially in the region of the high field.

  6. [Urological emergencies].

    Science.gov (United States)

    Danuser, H; Ackermann, D K; Studer, U E

    1993-04-17

    Every general practitioner has to deal with urologic emergencies. The most frequent illnesses are urinary retention, acute scrotum, priapism, macrohematuria, nephritic colic, obstructive pyelonephritis and pyonephrosis. Whereas urinary retention, as well as acute ureteric stone colic must generally be treated by the practitioner, the urologist must often be consulted in case of an acute scrotum or for priapism. Testicular torsion is one situation, where surgical treatment needs to be performed within 6 hours. Of utmost importance is his timely assistance with the obstructive pyelonephritis and pyonephrosis. These are initially often not recognized, especially because the first ultrasound examination of the intrarenal pyelone may not show a dilatation of the collecting system despite obstruction. If the adequate treatment with drainage and antibiotics is applied too late, this can result in serious and potentially lethal consequences.

  7. Ordered Rate Constitutive Theories: Development of Rate Constitutive Equations for Solids, Liquids, and Gases

    Science.gov (United States)

    2010-08-18

    in the Months of June, July, and August, 1827, on the Particles Contained in the Pollen of Plants ; and on the General Existence of Active Molecules in...time derivatives of the Cauchy stress tensors and strain tensors . . . . . . . 17 3 Conservation laws... conservation laws [1, 2] is inde- pendent of the constitution of the matter. The stress field and heat vector are assumed to be a consequence of kinematics of

  8. Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors [v1; ref status: indexed, http://f1000r.es/z6

    Directory of Open Access Journals (Sweden)

    Thomas B Kepler

    2013-04-01

    Full Text Available One of the key phenomena in the adaptive immune response to infection and immunization is affinity maturation, during which antibody genes are mutated and selected, typically resulting in a substantial increase in binding affinity to the eliciting antigen. Advances in technology on several fronts have made it possible to clone large numbers of heavy-chain light-chain pairs from individual B cells and thereby identify whole sets of clonally related antibodies. These collections could provide the information necessary to reconstruct their own history - the sequence of changes introduced into the lineage during the development of the clone - and to study affinity maturation in detail. But the success of such a program depends entirely on accurately inferring the founding ancestor and the other unobserved intermediates. Given a set of clonally related immunoglobulin V-region genes, the method described here allows one to compute the posterior distribution over their possible ancestors, thereby giving a thorough accounting of the uncertainty inherent in the reconstruction. I demonstrate the application of this method on heavy-chain and light-chain clones, assess the reliability of the inference, and discuss the sources of uncertainty.

  9. Identification of radically different variants of porcine reproductive and respiratory syndrome virus in Eastern Europe: towards a common ancestor for European and American viruses.

    Science.gov (United States)

    Stadejek, T; Stankevicius, A; Storgaard, T; Oleksiewicz, M B; Belák, S; Drew, T W; Pejsak, Z

    2002-08-01

    We determined 22 partial porcine reproductive and respiratory syndrome virus (PRRSV) ORF5 sequences, representing pathogenic field strains mainly from Poland and Lithuania, and two currently available European-type live PRRSV vaccines. Also, the complete ORF7 of two Lithuanian and two Polish strains was sequenced. We found that Polish, and in particular Lithuanian, PRRSV sequences were exceptionally different from the European prototype, the Lelystad virus, and in addition showed a very high national diversity. The most diverse present-day European-type PRRSV sequences were from Poland (2000) and Lithuania (2000), and exhibited only 72.2% nucleotide identity in the investigated ORF5 sequence. While all sequences determined in the present study were clearly of European type, inclusion of the new Lithuanian sequences in the genealogy resulted in a common ancestor for the European type virus significantly closer to the American-type PRRSV than previously seen. In addition, the length of the ORF7 of the Lithuanian strains was 378 nucleotides, and thus intermediate between the sizes of the prototypical EU-type (387 nucleotides) and US-type (372 nucleotides) ORF7 lengths. These findings for the Lithuanian PRRSV sequences provide support for the hypothesis that the EU and US genotypes of PRRSV evolved from a common ancestor. Also, this is the first report of ORF7 protein size polymorphism in field isolates of EU-type PRRSV.

  10. Reconstructed ancestral Myo-inositol-3-phosphate synthases indicate that ancestors of the Thermococcales and Thermotoga species were more thermophilic than their descendants.

    Directory of Open Access Journals (Sweden)

    Nicholas C Butzin

    Full Text Available The bacterial genomes of Thermotoga species show evidence of significant interdomain horizontal gene transfer from the Archaea. Members of this genus acquired many genes from the Thermococcales, which grow at higher temperatures than Thermotoga species. In order to study the functional history of an interdomain horizontally acquired gene we used ancestral sequence reconstruction to examine the thermal characteristics of reconstructed ancestral proteins of the Thermotoga lineage and its archaeal donors. Several ancestral sequence reconstruction methods were used to determine the possible sequences of the ancestral Thermotoga and Archaea myo-inositol-3-phosphate synthase (MIPS. These sequences were predicted to be more thermostable than the extant proteins using an established sequence composition method. We verified these computational predictions by measuring the activities and thermostabilities of purified proteins from the Thermotoga and the Thermococcales species, and eight ancestral reconstructed proteins. We found that the ancestral proteins from both the archaeal donor and the Thermotoga most recent common ancestor recipient were more thermostable than their descendants. We show that there is a correlation between the thermostability of MIPS protein and the optimal growth temperature (OGT of its host, which suggests that the OGT of the ancestors of these species of Archaea and the Thermotoga grew at higher OGTs than their descendants.

  11. 祖先崇拜的生命价值观及其现代审视%The Life Value in Ancestor Worship and its Modern Evaluation

    Institute of Scientific and Technical Information of China (English)

    赖萱萱

    2014-01-01

    Essentially,the religious behavior of ancestor worship is based on repaying to life origin, which affirmed the value of life.The article discusses valuing life and respecting life in the outlook of ancestor worship’s life value,it shows concretely as follows:treasuring life in sacrificial rites in the ancesters’temples,cherishing life in daily life,and caring for life in ritual of bereaved.Its life spirit is of modern value.%祖先崇拜的宗教行为本质上是基于对生命始源“生生之德”的感恩和报答,它肯定了生命存在的价值和意义。尊生重生是祖先崇拜生命价值观的基本向度,具体体现在宗庙祭祀中的生命保护、日常生活中的生命珍视和丧葬仪式中的生命关怀,其蕴含的“伦理化”生命意识与“人性化”生命关怀可为当代社会树立科学的生命观及建构合理的临终关怀体系所资取。

  12. Sovereignty, globalization and the constitution of meaning

    Directory of Open Access Journals (Sweden)

    Farid Samir Benavides Vanegas

    2015-06-01

    Full Text Available In this essay I wish to show how law’s and the nation’s loss of sovereignty have meant the emergence of new sites of identity construction and how these new identities have become global due to the loss of centrality of the nation state as a place of meaning production. By analyzing the concept of sovereignty and its relation to the power of naming held by the State, and exercised through the law, I want to show how in a society of the spectacle that power is removed from the State and given to other places that can ensure passivity of viewers and thus the absence of resistance in the construction of meaning. This I will do by analyzing a Colombian soap opera and its handling of the concept of corruption to show legal meaning was overtaken by the one built in the media.

  13. Constitution Gardens%宪法花园

    Institute of Scientific and Technical Information of China (English)

    彼得·沃克合伙人风景园林事务所(撰文); 章健玲(翻译)

    2012-01-01

      The National Mall the most visited national park in US, with more than 25 mil ion annual visitors and 3,000 annual permitted events. This 700-acre park was not built to withstand this level of use and has not received adequate resources to be restored. To gain more guests and visitor, This National mal is going to be redesigned for its three prominent locations including Constitution Gardens, Sylvan Theater at the Washington Monument Grounds, and The Union Square. To accomplish these goals the Trust for the National Mal is sponsoring a design competition for three key areas on the National Mal . The competition kicked off on September 8th, 2011 and after the jury-evaluation, public exhibition and interviews, the winners were announced on May 3rd, 2012. The competition winners are:Rogers Marvel Architects+Peter Walker and Partners(Constitution Gardens), OLIN+Weiss/Manfredi(Sylvan Theater at the Washington Monument Grounds) and Gustafson Guthrie Nichol+Davis Brody Bond(Union Square).With the support of National Mall Trust, the three winning proposals are featured in this issue .%  国家广场是美国最受欢迎的国家公园,每年共接待游客2500万人次,共举办3000次合法活动。然而,这个占地700英亩(约283hm2)的公园一直未能满足现实的使用需求,也没有得到足够的资金来进行改善。为了提高游客流量,美国国家广场将对它的三个重要景点宪法花园、森林剧场和联合广场进行改造。为此,国家广场基金会组织了一个设计竞赛,该设计竞赛于2011年9月8日开始接受报名,经过方案提交,评委评审,公示和采访等阶段,于2012年5月8日公布中标方案。其中,彼得·沃克合伙人风景园林事务所与罗杰斯·马威尔建筑师事务所联合体、欧林事务所+韦斯/曼尼弗莱德事务所联合体和古斯塔夫森·古斐利·妮可事务所+戴维斯·布拉迪·邦德事务所联合体分别为宪法花园、森林

  14. Nonlinear constitutive behavior of ferroelectric materials

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The ferroelectric specimen is considered as an aggregation of many randomly oriented domains. According to this mechanism,a multi-domain mechanical model is developed in this paper. Each domain is represented by one element. The applied stress and electric field are taken to be the stress and electric field in the formula of the driving force of domain switching for each element in the specimen. It means that the macroscopic switching criterion is used for calculating the volume fraction of domain switching for each element. By using the hardening relation between the driving force of domain switching and the volume fraction of domain switching calibrated,the volume fraction of domain switching for each element is calculated. Substituting the stress and electric field and the volume fraction of domain switching into the constitutive equation of ferroelectric material,one can easily get the strain and electric displacement for each element. The macroscopic behavior of the ferroelectric specimen is then directly calculated by volume averaging. Mean-while,the nonlinear finite element analysis for the ferroelectric specimen is carried out. In the finite element simulation,the volume fraction of domain switching for each element is calculated by using the same method mentioned above. The in-teraction between different elements is taken into account in the finite element simulation and the local stress and electric field for each element is obtained. The macroscopic behavior of the specimen is then calculated by volume averaging. The computation results involve the electric butterfly shaped curves of axial strain versus the axial electric field and the hysteresis loops of electric displacement versus the electric field for ferroelectric specimens under the uniaxial coupled stress and electric field loading. The present theoretical prediction agrees reasonably with the experimental results.

  15. How Does Astronomy Constitute A Learning Community?

    Science.gov (United States)

    Dogan, Yasemin; Sengul, R.; Unat, O.; Aknil, A.; Gurel, Z.

    2010-01-01

    This study was conducted in Turkey within an interdisciplinary project called "From a windowless home to a skyscraper: Let's build a home". It was realized through collaboration between a public university and a private high school. Researchers from Physics Education Department and volunteer teachers from high school, each studying on a different discipline, and volunteer high school students, all from an urban area of the country, conducted the project in a rural small town with resident secondary school students. It was implemented on the basis of history, through the use of different fields such as science, mathematics, geography, art, handcraft, architecture, engineering and astronomy in August 2008. The purpose of this study was to present the effect of the astronomical activities involved in the project. These implementations constructed a scientific and social base for the framework of astronomical activities of IYA2009, including building an amateur observatory. Since today's people are not so much acquainted with the issues of space and astronomy as much as the people of Antiquity, we attached special importance to the efforts in this field. The project, proceeded by a preparatory and informative period, involved night sky observation, initially with naked eye, followed by observation through telescope. Not only the students but also countless people, old or young, participated in our work in the field of astronomy. It provided a chance for all the people participating in or connected to the project to discover the sky. Astronomical activities aroused curiosity among students and the community and made a difference by inducing an awareness of the sky. The participants of the study had completely different social and cultural backgrounds, and this study removed all these differences bringing them together under the overarching astronomical and historical aspect. Moreover the community revealed all the characteristics that constitute a learning community.

  16. How Long Can France’s State of Emergency Last?

    OpenAIRE

    Chabal, Emile

    2016-01-01

    France’s state of emergency in the wake of the Paris terrorist attacks has been predominately intended as a measure of public reassurance, writes Emile Chabal. He suggests that current efforts to enshrine the state of emergency provisions into the French constitution ignore its ineffectiveness and its problematic colonial origins.

  17. Report between the President and Constitutional Court and its influence on the functioning of the Constitutional System in Kosovo

    Directory of Open Access Journals (Sweden)

    Florent Muçaj

    2016-07-01

    Full Text Available This paper aims at clarifying the report between the President and the Constitutional Court. If we take as a starting point the constitutional mandate of these two institutions it follows that their final mission is the same, i.e., the protection and safeguarding of the constitutional system. This paper, thus, will clarify the key points in which this report is expressed. Further, this paper examines the theoretical aspects of the report between the President and the Constitutional Court, starting from the debate over this issue between Karl Schmitt and Hans Kelsen. An important part of the paper will examine the Constitution of Kosovo, i.e., the contents of the constitutional norm and its application. The analysis focuses on the role such report between the two institutions has on the functioning of the constitutional system. In analyzing the case of Kosovo, this paper examines Constitutional Court cases in which the report between the President and the Constitutional Court has been an issue of review. Such cases assist us in clarifying the main theme of this paper. Therefore, the reader will be able to understand the key elements of the report between the President as a representative of the unity of the people on the one hand and the Constitutional Court as a guarantor of constitutionality on the other hand.

  18. 77 FR 63309 - Constitution Pipeline Company, LLC; Notice of Public Scoping Meeting and Extension of Scoping...

    Science.gov (United States)

    2012-10-16

    ... Energy Regulatory Commission Constitution Pipeline Company, LLC; Notice of Public Scoping Meeting and Extension of Scoping Period for the Planned Constitution Pipeline Project On October 24, 2012, the Federal... Constitution Pipeline Company's (Constitution) Constitution Pipeline Project. This notice also extends...

  19. What constitutes our understanding of a patient?

    Science.gov (United States)

    Chessick, R D

    1993-01-01

    aspects of prevailing ideologies in constituting and determining what we call truth and understanding, including the "understanding" of a patient in psychotherapy. An example of the postmodern blend of philosophy and psychoanalysis is presented by Arlow's emphasis on unconscious fantasies and his insightful comments on how these unconscious fantasies organize and determine what we experience from the very beginning of life. This I believe is most consistent with Rescher's philosophical notion of "conceptual idealism," also briefly reviewed in this paper.(ABSTRACT TRUNCATED AT 400 WORDS)

  20. Predominant constitutive CFTR conductance in small airways

    Directory of Open Access Journals (Sweden)

    Lytle Christian

    2005-01-01

    Full Text Available Abstract Background The pathological hallmarks of chronic obstructive pulmonary disease (COPD are inflammation of the small airways (bronchiolitis and destruction of lung parenchyma (emphysema. These forms of disease arise from chronic prolonged infections, which are usually never present in the normal lung. Despite the fact that primary hygiene and defense of the airways presumably requires a well controlled fluid environment on the surface of the bronchiolar airway, very little is known of the fluid and electrolyte transport properties of airways of less than a few mm diameter. Methods We introduce a novel approach to examine some of these properties in a preparation of minimally traumatized porcine bronchioles of about 1 mm diameter by microperfusing the intact bronchiole. Results In bilateral isotonic NaCl Ringer solutions, the spontaneous transepithelial potential (TEP; lumen to bath of the bronchiole was small (mean ± sem: -3 ± 1 mV; n = 25, but when gluconate replaced luminal Cl-, the bionic Cl- diffusion potentials (-58 ± 3 mV; n = 25 were as large as -90 mV. TEP diffusion potentials from 2:1 NaCl dilution showed that epithelial Cl- permeability was at least 5 times greater than Na+ permeability. The anion selectivity sequence was similar to that of CFTR. The bionic TEP became more electronegative with stimulation by luminal forskolin (5 μM+IBMX (100 μM, ATP (100 μM, or adenosine (100 μM, but not by ionomycin. The TEP was partially inhibited by NPPB (100 μM, GlyH-101* (5–50 μM, and CFTRInh-172* (5 μM. RT-PCR gave identifying products for CFTR, α-, β-, and γ-ENaC and NKCC1. Antibodies to CFTR localized specifically to the epithelial cells lining the lumen of the small airways. Conclusion These results indicate that the small airway of the pig is characterized by a constitutively active Cl- conductance that is most likely due to CFTR.

  1. The genetic basis of constitutive and herbivore-induced ESP-independent nitrile formation in Arabidopsis.

    Science.gov (United States)

    Burow, Meike; Losansky, Anja; Müller, René; Plock, Antje; Kliebenstein, Daniel J; Wittstock, Ute

    2009-01-01

    Glucosinolates are a group of thioglucosides that are components of an activated chemical defense found in the Brassicales. Plant tissue damage results in hydrolysis of glucosinolates by endogenous thioglucosidases known as myrosinases. Spontaneous rearrangement of the aglucone yields reactive isothiocyanates that are toxic to many organisms. In the presence of specifier proteins, alternative products, namely epithionitriles, simple nitriles, and thiocyanates with different biological activities, are formed at the expense of isothiocyanates. Recently, simple nitriles were recognized to serve distinct functions in plant-insect interactions. Here, we show that simple nitrile formation in Arabidopsis (Arabidopsis thaliana) ecotype Columbia-0 rosette leaves increases in response to herbivory and that this increase is independent of the known epithiospecifier protein (ESP). We combined phylogenetic analysis, a screen of Arabidopsis mutants, recombinant protein characterization, and expression quantitative trait locus mapping to identify a gene encoding a nitrile-specifier protein (NSP) responsible for constitutive and herbivore-induced simple nitrile formation in Columbia-0 rosette leaves. AtNSP1 is one of five Arabidopsis ESP homologues that promote simple nitrile, but not epithionitrile or thiocyanate, formation. Four of these homologues possess one or two lectin-like jacalin domains, which share a common ancestry with the jacalin domains of the putative Arabidopsis myrosinase-binding proteins MBP1 and MBP2. A sixth ESP homologue lacked specifier activity and likely represents the ancestor of the gene family with a different biochemical function. By illuminating the genetic and biochemical bases of simple nitrile formation, our study provides new insights into the evolution of metabolic diversity in a complex plant defense system.

  2. Constitutional Crowdsourcing to Reconcile Demos with Aristos and Nomos

    DEFF Research Database (Denmark)

    Abat Ninet, Antoni

    2015-01-01

    After the failed Icelandic experience of constitutional crowdsourcing (2009-2012), some of the country’s legal community, parliamentarians and policymakers affirmed that the constitutional draft proposed by the constitutional council of 25 citizens and approved unanimously on 27 July 2011......, was unrealistic, unenforceable and against the legal and political tradition of the Nordic country. According to these legal experts, the final approval of that constitutional draft would have plunged the country into a totally unstable legal situation. The fully ex-novo character of the constitution would also...... disenable the judges to use jurisprudence to resolve the legal penumbras created by the potential application of the text. The people of Iceland focused excessively on the constitutional accommodation of human rights, leaving aside other essential factors that a constituent process might take off...

  3. Disentangling Network and Global Effects in Constitutional Political Development

    CERN Document Server

    Rutherford, Alex; Cebrian, Manuel; Rahwan, Iyad; LeVeck, Brad; Garcia-Herranz, Manuel

    2016-01-01

    Constitutions reflect the character and history of countries, particularly colonial legacy. While legal systems and constitutional texts are often 'nherited' from a former coloniser, until now this has not been quantified and interplay with global policy trends and horizontal influence not well understood. In this paper we analyse the structure and dynamics of all national constitutions using text similarity measures and network analysis. We attempt to answer the question 'what is the interplay between colonial history and global, time varying trends in determining the characteristics of a country's constitution?'. We identify strong trends, regardless of colonial history, in constitutional activity. We demonstrate that inheritance is strong, that countries with shared colonial history subscribe to `topics` of related constitutional provisions in a predictable manner, with respect to colonial history. Finally, we identify provisions whose adoption is determined by colonial history and others which are determi...

  4. The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals

    Directory of Open Access Journals (Sweden)

    Andrésdóttir Valgerdur

    2008-11-01

    Full Text Available Abstract Background APOBEC3 (A3 proteins deaminate DNA cytosines and block the replication of retroviruses and retrotransposons. Each A3 gene encodes a protein with one or two conserved zinc-coordinating motifs (Z1, Z2 or Z3. The presence of one A3 gene in mice (Z2–Z3 and seven in humans, A3A-H (Z1a, Z2a-Z1b, Z2b, Z2c-Z2d, Z2e-Z2f, Z2g-Z1c, Z3, suggests extraordinary evolutionary flexibility. To gain insights into the mechanism and timing of A3 gene expansion and into the functional modularity of these genes, we analyzed the genomic sequences, expressed cDNAs and activities of the full A3 repertoire of three artiodactyl lineages: sheep, cattle and pigs. Results Sheep and cattle have three A3 genes, A3Z1, A3Z2 and A3Z3, whereas pigs only have two, A3Z2 and A3Z3. A comparison between domestic and wild pigs indicated that A3Z1 was deleted in the pig lineage. In all three species, read-through transcription and alternative splicing also produced a catalytically active double domain A3Z2-Z3 protein that had a distinct cytoplasmic localization. Thus, the three A3 genes of sheep and cattle encode four conserved and active proteins. These data, together with phylogenetic analyses, indicated that a similar, functionally modular A3 repertoire existed in the common ancestor of artiodactyls and primates (i.e., the ancestor of placental mammals. This mammalian ancestor therefore possessed the minimal A3 gene set, Z1-Z2-Z3, required to evolve through a remarkable series of eight recombination events into the present day eleven Z domain human repertoire. Conclusion The dynamic recombination-filled history of the mammalian A3 genes is consistent with the modular nature of the locus and a model in which most of these events (especially the expansions were selected by ancient pathogenic retrovirus infections.

  5. Ancestor of the new archetypal biology: Goethe's dynamic typology as a model for contemporary evolutionary developmental biology.

    Science.gov (United States)

    Riegner, Mark F

    2013-12-01

    As understood historically, typological thinking has no place in evolutionary biology since its conceptual framework is viewed as incompatible with population thinking. In this article, I propose that what I describe as dynamic typological thinking has been confused with, and has been overshadowed by, a static form of typological thinking. This conflation results from an inability to grasp dynamic typological thinking due to the overlooked requirement to engage our cognitive activity in an unfamiliar way. Thus, analytical thinking alone is unsuited to comprehend the nature of dynamic typological thinking. Over 200 years ago, J. W. von Goethe, in his Metamorphosis of Plants (1790) and other writings, introduced a dynamic form of typological thinking that has been traditionally misunderstood and misrepresented. I describe in detail Goethe's phenomenological methodology and its contemporary value in understanding morphological patterns in living organisms. Furthermore, contrary to the implications of static typological thinking, dynamic typological thinking is perfectly compatible with evolutionary dynamics and, if rightly understood, can contribute significantly to the still emerging field of evolutionary developmental biology (evo-devo).

  6. Constitutive phosphorylation of Shc proteins in human tumors

    DEFF Research Database (Denmark)

    Pelicci, G; Lanfrancone, L; Salcini, A E

    1995-01-01

    cells. In tumor cells with known TK gene alterations Shc proteins were constitutively phosphorylated and complexed with the activated TK. No constitutive Shc phosphorylation was found in primary cell cultures and normal tissues. In 14 of 27 tumor cell lines with no reported TK alterations, Shc proteins...... activated TKs and that the analysis of Shc phosphorylation allow the identification of tumors with constitutive TK activation....

  7. [The right to live one's own death and its constitutionality].

    Science.gov (United States)

    Bussinguer, Elda Coelho de Azevedo; Barcellos, Igor Awad

    2013-09-01

    The article seeks to reflect on the legality of the early manifestation of will, established in Brazil through Resolution No. 1.995/12 of the Federal Council of Medicine in the face of the legislative omission and considering the possible linkage of physicians and relatives of terminally ill patients in drafting the Last Will and Testament. It examines the constitutionality of these policies and, therefore, the constitutionality of the resolution itself in light of the new Brazilian constitutional paradigm.

  8. Enacting and Re-Enacting the Constitution of Development

    DEFF Research Database (Denmark)

    Brønnum, Louise; Clausen, Christian

    2015-01-01

    study that will show how there in a development company exits a constitution of development. This constitution of development is perceived as a set of development rules and guidelines that are implicitly enacted by the employees and for certain development opportunities. Through the case study we...... will present different strategies for re-enactment of the constitution of development that frame for alternative development spaces with perceived different rules, and therefor make space for the development of a more radical nature....

  9. Identification of radically different variants of porcine reproductive and respiratory syndrome virus in Eastern Europe: towards a common ancestor for European and American viruses

    DEFF Research Database (Denmark)

    Stadejek, T.; Stankevicius, A.; Storgaard, Torben;

    2002-01-01

    We determined 22 partial porcine reproductive and respiratory syndrome virus (PRRSV) ORF5 sequences, representing pathogenic field strains mainly from Poland and Lithuania, and two currently available European-type live PRRSV vaccines. Also, the complete ORF7 of two Lithuanian and two Polish......) and Lithuania (2000), and exhibited only 72(.)2% nucleotide identity in the investigated ORF5 sequence. While all sequences determined in the present study were clearly of European type, inclusion of the new Lithuanian sequences in the genealogy resulted in a common ancestor for the European type virus...... significantly closer to the American-type PRRSV than previously seen. In addition, the length of the ORF7 of the Lithuanian strains was 378 nucleotides, and thus intermediate between the sizes of the prototypical EU-type (387 nucleotides) and US-type (372 nucleotides) ORF7 lengths. These findings...

  10. [[The apothecaries of the district of Les Halles in Paris in the 17th century. Molière's ancestors in Les Halles].

    Science.gov (United States)

    Warolin, Christian

    2016-03-01

    Les Halles were created by King Louis VI at the begining of the 12th century as a central market for food and trade. Apothecaries conducted their trade there from that time. In the 17th century, eleven apothecaries were established in this district, bordered on the south by the rue Saint-Honoré, on the east by the rue Saint-Denis, on the west by the rue de la Tonnellerie, and the north by the rue Montmartre. Their biographies have been analysed, and the data that has been collected has enabled their précise location to be fixed on a map of 1700. Molière's ancestors, both maternal (the Cressé family) and paternal (the Pocquelin's), lived in this district. Details of their relationships with their apothecary neighbours have been revealed.

  11. Constitutionalism and conflict in Ternate, North Maluku, Indonesia

    NARCIS (Netherlands)

    Hermkens, A.K.

    2010-01-01

    Allegedly the oldest in Indonesia, and to some even beyond, the constitution treasured in the Kedaton (traditional palace) of the Sultan of Ternate (North Maluku, Indonesia) constitutes a dividing line between North and South Ternate in terms of government, ethnicity, and, spirituality. Moreover, it

  12. The Constitutionality of School Choice in New Hampshire

    Science.gov (United States)

    Douglas, Charles G., III; Komer, Richard D.

    2004-01-01

    Does a "school choice" program, under which state funds are disbursed on a neutral basis to parents in the form of a voucher to defray the cost of sending their children to a school of their choice, run afoul of the Establishment Clause of the First Amendment to the United States Constitution, or of the New Hampshire Constitution? No. A…

  13. Constitutional obligations of a person and a citizen

    Directory of Open Access Journals (Sweden)

    Alexey Yu. Ogurtsov

    2011-01-01

    Full Text Available The constitution of the Russian Federation does not contain the list of obligations, but theoretically each legal right is supposed to correspond to a legal obligation. Such conformity is achieved by means of attaching obligations not only by Constitution, but by the branch legislation either.

  14. Equality v. Liberty v. Pluralism: Latinos in American Constitutional Law.

    Science.gov (United States)

    Soltero, Carlos R.

    This paper examines how U.S. courts, particularly the Supreme Court, have applied constitutional law principles to Latino communities and individuals in three areas: public education, the status of Puerto Rico, and jury selection. Consistent with traditional views of American society as biracial (black and white), constitutional law discussions…

  15. Living Democracy: How Constitution High School Molds Better Citizens

    Science.gov (United States)

    Brasof, Marc

    2009-01-01

    Philadelphia's Constitution High School (CHS) is committed both to the theory of education for democracy, and to its practice, as reflected by a school constitution, student elections, town hall meetings, and active student participation in school government. As its name indicates, CHS is a theme-based high school that focuses on history,…

  16. What Constitution Day Means and Why It Matters

    Science.gov (United States)

    Jamieson, Kathleen Hall

    2014-01-01

    For almost three quarters of a century, advocates have worked to give comparable federal stature to September 17, the day on which we celebrate the anniversary of the 1787 signing of the U.S. Constitution by the nation's founders. As President John F. Kennedy noted in his 1961 Constitution Day proclamation, it is a day for…

  17. New constitutive model for the study of creeping solids

    Institute of Scientific and Technical Information of China (English)

    王世文; 杨兆建; 冯建玲

    2002-01-01

    In this paper, a incremental form of constitutive laws for creeping studies are proposed. The equations are based on the concept of creep hardening surface. Damage effects were introduced to the new constitutive relations to study solids creeping effects with pre-existing damages. The present formula is easy to be adopted into other numerical procedures such as finite element methods.

  18. Educational Research as a Reflexive Science of Constitution

    Science.gov (United States)

    Packer, Martin

    2010-01-01

    "Constitution" is a relationship of mutual formation between people and their form of life. Neither can exist without the other. In the 1970s, proposals were made in various social sciences, including anthropology, political science, and sociology, for a new kind of inquiry that would focus squarely on constitution. It would be an explicitly…

  19. Europe-building through private law. Lessons from constitutional theory

    NARCIS (Netherlands)

    C. Mak

    2012-01-01

    Abstract: Questioning the link between private law and the nation-state that is implied by nationalist perceptions of the law, this paper seeks to find support for a transnational (Europeanist,constitutional-patriotist or cosmopolitan) view on private law in constitutional theory. Normative theories

  20. Constitutive Modeling of Geomaterials Advances and New Applications

    CERN Document Server

    Zhang, Jian-Min; Zheng, Hong; Yao, Yangping

    2013-01-01

    The Second International Symposium on Constitutive Modeling of Geomaterials: Advances and New Applications (IS-Model 2012), is to be held in Beijing, China, during October 15-16, 2012. The symposium is organized by Tsinghua University, the International Association for Computer Methods and Advances in Geomechanics (IACMAG), the Committee of Numerical and Physical Modeling of Rock Mass, Chinese Society for Rock Mechanics and Engineering, and the Committee of Constitutive Relations and Strength Theory, China Institution of Soil Mechanics and Geotechnical Engineering, China Civil Engineering Society. This Symposium follows the first successful International Workshop on Constitutive Modeling held in Hong Kong, which was organized by Prof. JH Yin in 2007.   Constitutive modeling of geomaterials has been an active research area for a long period of time. Different approaches have been used in the development of various constitutive models. A number of models have been implemented in the numerical analyses of geote...

  1. Emergency teams in Danish emergency departments

    DEFF Research Database (Denmark)

    Lafrenz, Thomas; Lindberg, Søren Østergaard; La Cour, Jeppe Lerche;

    2012-01-01

    The use of designated emergency teams for cardiac arrest and trauma patients is widely implemented. However, the use of designated teams in Danish emergency departments (EDs) has not been investigated. Our aim was to investigate the use and staffing of emergency teams in Danish EDs....

  2. The brazilian constitution as third generation product: convergence and differences between the latin american constitutionalism and legal garantism theory

    Directory of Open Access Journals (Sweden)

    Luiz Henrique Urquhart Cademartori

    2015-12-01

    Full Text Available This article addresses the phenomenon of the latinamerican constitutionalism, its characteristics, critical issues and its challenges facing the European constitutional models, such as the legal garantism and neoconstitutionalism. That being said, this work compares the recent theoretical proposals within the Latin American constitutional theory with the European tradition. In this way, we delimit the aspects of main Latin American constitutionalism theory and contrast European constitutional theories, such as Ferrajoli’s legal garantism and representatives of neoconstitutionalism such as Dworkin, Alexy, Müller and Haberle. In this work, we seek to understand and explain the so-called "third generation constitutions”, in order to think properly of the Brazilian constitutionalism and the influence of the new legal institutions and procedural safeguards contained in our Constitution which give means to make possible fundamental and social rights. After that, we examine the affinities that Latin American constitutionalism has found in the legal garantism theory, which enables fundamental and social rights, and which has been largely accepted in countries similar to Brazil despite of its European origins.

  3. The Obligations on Government and Society in our Constitutional State to Respect and Support Independent Constitutional Structures

    Directory of Open Access Journals (Sweden)

    LWH Ackermann

    2000-05-01

    Full Text Available Constitutional democracy recognises the ancient democratic principle that government of a country is based on and legitimated by the will and consent of the governed, which is determined by regular multi-party elections based on universal adult franchise. Constitutional democracy limits this principle by subjecting the democratically elected government and the will of the majority subject to a written constitution and the norms embodied in it. Such constitution is enshrined as the supreme law of the country in question. An almost universal feature of modern constitutionalism is a Bill of Rights that forms part of the Constitution and which is designed to protect and enforce individual rights principally, although not exclusively, against the state. Constitutionalism also embodies the principle of the separation of powers. A competent and independent judiciary, with the power to review all legislative and executive conduct that is inconsistent with the Constitution, is regarded, almost universally, as the prime and most effective check on the legislative and executive branches of government. Recently it has come to be realised that for the truly effective and meaningful operation of constitutionalism, other independent state institutions are necessary. The collective objective of these institutions is to ensure that the Constitution in fact produces what it proclaims: that constitutionalism becomes a way of life in all institutional structures. The South African Constitution has clearly designated the judiciary as the prime upholder and enforcer of the Constitution. The Constitution has, however, gone further and makes provision for a variety of independent state institutions whose purpose is to "strengthen constitutional democracy in the Republic". Apart from these state institutions the Constitution also makes provision for other independent bodies designed to play an important checking and balancing role. The regular effective functioning of

  4. CONSTITUTIVE RELATION OF UNSATURATED SOIL BY USE OF THE MIXTURE THEORY(I)—NONLINEAR CONSTITUTIVE EQUATIONS AND FIELD EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    HUANGYi; ZHANGYin-ke

    2003-01-01

    The nonlinear constitutive equations and field equations of unsaturated soils were constructed on the basis of mixture theory.The soils were treated as the mixture composed of three constituents.First ,from the researches of soil mechanics,some basic assumptions about the unsaturated soil mixture were mode,and the entropy inequality unsaturated soil mixture was derived.Then,with the common method usually used to deal with the constitutive problems in mixture theory,the nonlinear constitutive equations were obtained.Finally,putting the constiutive equtions of constituents into the balance equations of momentum,the nonlinear field equations of constitutents into the balance equations of momentum,the nonliear field equations of constitutents were set up.The balance equation of energy of unsaturated soil was also given,and thus the complete equations for solving the thermodynamic process of unsaturated soil was formed.

  5. Systems and synthetic biology as emerging technosciences

    Directory of Open Access Journals (Sweden)

    Karen Kastenhofer

    2016-12-01

    Full Text Available Systems and synthetic biology can be understood as emerging technosciences. Both are characteristically shaped by promises and visions, a certain logic and function of labelling, specific forms of social organisation, an embedding in specific regimes of funding and innovation as well as a characteristic matrix of orientations within research practice. This characteristic constitution of systems and synthetic biology has fundamental consequences for scientific practice, its analysis and its governance.

  6. [Pediatric emergencies in the emergency medical service].

    Science.gov (United States)

    Silbereisen, C; Hoffmann, F

    2015-01-01

    Out-of-hospital pediatric emergencies occur rarely but are feared among medical personnel. The particular characteristics of pediatric cases, especially the unaccustomed anatomy of the child as well as the necessity to adapt the drug doses to the little patient's body weight, produce high cognitive and emotional pressure. In an emergency standardized algorithms can facilitate a structured diagnostic and therapeutic approach. The aim of this article is to provide standardized procedures for the most common pediatric emergencies. In Germany, respiratory problems, seizures and analgesia due to trauma represent the most common emergency responses. This article provides a practical approach concerning the diagnostics and therapy of emergencies involving children.

  7. La légitimité de la Constitution dans la doctrine constitutionnelle japonaise The Legality of the Constitution in the Japanese constitutional Doctrine

    Directory of Open Access Journals (Sweden)

    Simon Serverin

    2010-07-01

    Full Text Available La Constitution japonaise, promulguée en novembre 1946 et entrée en vigueur en mai 1947, pose à la théorie constitutionnelle un certain nombre de problèmes qui ne sont toujours pas résolus. Adoptée sous occupation américaine, rédigée par les services du GHQ dirigés par le général MacArthur, la Constitution a en outre été promulguée comme une simple révision de la Charte impériale de 1889, dite Constitution de Meiji, alors que par les principes démocratiques nouveaux qu’elle instaurait, elle p...

  8. Emergency Medical Services

    Science.gov (United States)

    ... and need help right away, you should use emergency medical services. These services use specially trained people and specially equipped facilities. You may need care in the hospital emergency room (ER). Doctors and nurses there treat emergencies, ...

  9. Emergency care toolkits.

    Science.gov (United States)

    Black, Steven

    2004-06-01

    Emergency care services are the focus of a series of toolkits developed by the NHS National electronic Library for Health to provide resources for emergency care leads and others involved in modernising emergency care, writes Steven Black.

  10. Elasto-plastic constitutive modeling for granular materials

    Institute of Scientific and Technical Information of China (English)

    彭芳乐; 李建中

    2004-01-01

    Based on the modified plastic strain energy approach, an elasto-plastic constitutive modeling for sand was proposed. The hardening function between the modified plastic strain energy and a stress parameter was presented, which was independent of stress history and stress paths. The proposed model was related to an isotropically work-hardening and softening, non-associated and elasto-plastic material description. It is shown that the constitutive modeling, the inherent and stress system-induced cross-anisotropic elasticity is also considered. The constitutive model is capable of simulating the effects on the deformation characteristics of stress history and stress path, pressure level and anisotropic strength.

  11. A study on peace principle of the constitution of Japan

    OpenAIRE

    1984-01-01

    In 1930s and 40s when I was a student and then a naval officer, whether Japan could offer any political principle for international society or not was an agonizing question to me. Apparently, the Constitution of Great Empire of Japan of 1889 did not have any, or rather it was forcing Japanese nation to be alienated from the world.The Constitution of Japan of 1946 is often called a 'peace constitution', having the sentences in paragraph 2 of its Preamble, which express pacifistic intention, an...

  12. Dynamic constitutive equation of GFRP obtained by Lagrange experiment

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The note presents a method of constructing dynamic constitutive equations of material by means of Lagrange experiment and analysis. Tests were carried out by a light gas gun and the stress history profiles were recorded on multiple Lagrange positions. The dynamic constitutive equations were deduced from the regression of a series of data which was obtained by Lagrange analysis based upon recorded multiple stress histories. Here constitutive equations of glass fibre reinforced phenolic resin composite(GFRP) in uniaxil strain state under dynamic loading are given. The proposed equations of the material agree well with experimental results.

  13. Constitutional design and political agency problems: the case of Colombia

    Directory of Open Access Journals (Sweden)

    Paola Alarcón López

    2014-06-01

    Full Text Available This article presents and explores, from a law and economics’ perspective, the Colombian Constitutional structures that create potential for corruption by undermining the checks and balances, the accountability system over politicians and in particular, by altering the computation of the agent once is facing the decision to act according to principal interest or behave in a corrupt way. A case study from a Colombian high court is presented in order to illustrate the interaction between the identified constitutional provisions to generate a scope for corruption. Finally, possible constitutional amendments are suggested in order to overcome these system failures.

  14. Constitutional design and political agency problems: the case of Colombia

    Directory of Open Access Journals (Sweden)

    Paola Alarcón López

    2014-07-01

    Full Text Available This article presents and explores, from a law and economics’ perspective, the Colombian Constitutional structures that create potential for corruption by undermining the checks and balances, the accountability system over politicians and in particular, by altering the computation of the agent once is facing the decision to act according to principal interest or behave in a corrupt way. A case study from a Colombian high court is presented in order to illustrate the interaction between the identified constitutional provisions to generate a scope for corruption. Finally, possible constitutional amendments are suggested in order to overcome these system failures.

  15. Stohastic Properties of Plasticity Based Constitutive Law for Concrete

    DEFF Research Database (Denmark)

    Frier, Christian; Sørensen, John Dalsgaard

    1998-01-01

    The purpose of this paper is to obtain a stochastic model for the parameters in a constitutive model for concrete based on associated plasticity theory and with emphasis placed on the pre-failure range. The constitutive model is based on a Drucker Prager yield surface augmented by a Rankine cut......-off criterion. The statistics of the material parameters are obtained by applying biaxial test results for plane concrete slabs to the constitutive model using the maximum likelihood method. Response surfaces are used to obtain the statistics for a parameter depending on other previously obtained parameters...

  16. Modernity, Rationality and Constitutional Law in Muslim-Majority Countries

    DEFF Research Database (Denmark)

    Abat Ninet, Antoni

    constitutions played in institutionalising a new sort of dominion in the newly established states. Against this background, the paper discusses the relationship between constitutionalism and Shari’a law, presenting this as a clash between two competing normative visions that are conceptually difficult......Are Islamic law, human rights and constitutionalism compatible? In answering this question, this paper first discusses the concept of modernity (understood in terms of rationality and standardization), analysing its abrupt implementation in the MENA countries and the role that the first modern...

  17. Law & psychiatry: Does the constitution require an insanity defense?

    Science.gov (United States)

    Appelbaum, Paul S

    2013-10-01

    Idaho is one of four states that have abolished the insanity defense. Hence, John Delling, on trial for two murders in Idaho, was unable to plead insanity or to argue that he lacked intent to kill, the only available option under Idaho law. After being sentenced to life in prison without parole, Delling challenged the constitutionality of Idaho's law. The state's supreme court rejected his appeal, holding that--despite the long history of the insanity defense and its widespread acceptance--there was no constitutional right to an insanity defense. Delling's petition to the U.S. Supreme Court was turned away, leaving the constitutional status of the insanity defense uncertain.

  18. Stochastic Properties of Plasticity Based Constitutive Law for Concrete

    DEFF Research Database (Denmark)

    Frier, Christian; Sørensen, John Dalsgaard

    The purpose of this paper is to obtain a stochastic model for the parameters in a constitutive model for concrete based on associated plasticity theory and with emphasis placed on the pre-failure range. The constitutive model is based on a Drucker Prager yield surface augmented by a Rankine cut......-off criterion. The statistics of the material parameters are obtained by applying biaxial test results for plane concrete slabs to the constitutive model using the maximum likelihood method. Response surfaces are used to obtain the statistics for a parameter depending on other previously obtained parameters...

  19. Organic Law Of Judicial Guarantees And Constitutional Control

    Directory of Open Access Journals (Sweden)

    Ernesto López Freire

    2013-01-01

    Full Text Available This paper demonstrates the various unconstitutional and fallacies of the Organic Law of Judicial guarantees and Constitutional Control. For that, there will be a comprehensive collation between the mentioned law and the Constitution of the Republic of Ecuador and force. Through this analysis shows a lack of knowledge of Ecuadorian law or legal science by their authors. This study elucidated, inter alia, the inconsistencies in matters relating to the interpretation of constitutional provisions, full compensation, material and integral; challenge administrative acts, judicial unit.

  20. An Integrated Theory of Constitutionalism in World Society

    DEFF Research Database (Denmark)

    Kjær, Poul F.

    Traditionally constitutional theory has relied on two central distinctions: The public/private and the national/transnational distinction. The societal developments of the past decades have however led to an increased erosion of these distinctions. In the academic literature, this development hav...... for compatibility between orders through constitutionalisation and the idea of constitutionalism as a way of approaching the future....... is formal organisations as such and not the particular type of formal organisation which is associated with statehood. Thus, they can be public or private, national or transnational. On this background, a distinction is introduced between the internal setup of constitutional orders, the external strive...

  1. Neural Network Model for the Constitutive Relations of Soil

    Institute of Scientific and Technical Information of China (English)

    Zeng Jing; Wang Jing-tao

    2003-01-01

    The soil constitutive relation is one of the important issues in soil mechanics. It is very difficult to establish mathematical models because of the complexity of soil mechanical behavior. We propose a new method of neural network analysis for establishing soil constitutive models. Based on triaxial experiments of sand in the laboratory, the nonlinear constitutive models of sand expressed by the neural network were set up. In comparison with Duncan-Chang's model, the neural network method for sand modeling has been proved to be more convenient, accurate and it has a strong fault-tolerance function.

  2. Constitutive theories on viscoelastoplasticity and damage of frozen soil

    Institute of Scientific and Technical Information of China (English)

    何平; 程国栋; 朱元林

    1999-01-01

    The constitutive theory on the viscoelastoplasticity and damage of frozen soil is based on the continuous mechanics and thermodynamics. The basic principles of the theory, dissipation potential function and damage model are presented. The constitutive theory explains the mechanical properties of frozen soils under complicated stresses, especially under high confining pressures which make frozen soil harden and soften. The agreement between the calculated results by the constitutive theory and the experimental results of triaxial creep of frozen soil is seen to be very good.

  3. Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors

    Directory of Open Access Journals (Sweden)

    Pavlov Youri I

    2009-03-01

    Full Text Available Abstract Background Evolution of DNA polymerases, the key enzymes of DNA replication and repair, is central to any reconstruction of the history of cellular life. However, the details of the evolutionary relationships between DNA polymerases of archaea and eukaryotes remain unresolved. Results We performed a comparative analysis of archaeal, eukaryotic, and bacterial B-family DNA polymerases, which are the main replicative polymerases in archaea and eukaryotes, combined with an analysis of domain architectures. Surprisingly, we found that eukaryotic Polymerase ε consists of two tandem exonuclease-polymerase modules, the active N-terminal module and a C-terminal module in which both enzymatic domains are inactivated. The two modules are only distantly related to each other, an observation that suggests the possibility that Pol ε evolved as a result of insertion and subsequent inactivation of a distinct polymerase, possibly, of bacterial descent, upstream of the C-terminal Zn-fingers, rather than by tandem duplication. The presence of an inactivated exonuclease-polymerase module in Pol ε parallels a similar inactivation of both enzymatic domains in a distinct family of archaeal B-family polymerases. The results of phylogenetic analysis indicate that eukaryotic B-family polymerases, most likely, originate from two distantly related archaeal B-family polymerases, one form giving rise to Pol ε, and the other one to the common ancestor of Pol α, Pol δ, and Pol ζ. The C-terminal Zn-fingers that are present in all eukaryotic B-family polymerases, unexpectedly, are homologous to the Zn-finger of archaeal D-family DNA polymerases that are otherwise unrelated to the B family. The Zn-finger of Polε shows a markedly greater similarity to the counterpart in archaeal PolD than the Zn-fingers of other eukaryotic B-family polymerases. Conclusion Evolution of eukaryotic DNA polymerases seems to have involved previously unnoticed complex events. We

  4. Emerging Pathogens Initiative (EPI)

    Data.gov (United States)

    Department of Veterans Affairs — The Emerging Pathogens Initiative (EPI) database contains emerging pathogens information from the local Veterans Affairs Medical Centers (VAMCs). The EPI software...

  5. Physical mapping of a large plant genome using global high-information-content-fingerprinting: the distal region of the wheat ancestor Aegilops tauschii chromosome 3DS

    Directory of Open Access Journals (Sweden)

    You Frank M

    2010-06-01

    Full Text Available Abstract Background Physical maps employing libraries of bacterial artificial chromosome (BAC clones are essential for comparative genomics and sequencing of large and repetitive genomes such as those of the hexaploid bread wheat. The diploid ancestor of the D-genome of hexaploid wheat (Triticum aestivum, Aegilops tauschii, is used as a resource for wheat genomics. The barley diploid genome also provides a good model for the Triticeae and T. aestivum since it is only slightly larger than the ancestor wheat D genome. Gene co-linearity between the grasses can be exploited by extrapolating from rice and Brachypodium distachyon to Ae. tauschii or barley, and then to wheat. Results We report the use of Ae. tauschii for the construction of the physical map of a large distal region of chromosome arm 3DS. A physical map of 25.4 Mb was constructed by anchoring BAC clones of Ae. tauschii with 85 EST on the Ae. tauschii and barley genetic maps. The 24 contigs were aligned to the rice and B. distachyon genomic sequences and a high density SNP genetic map of barley. As expected, the mapped region is highly collinear to the orthologous chromosome 1 in rice, chromosome 2 in B. distachyon and chromosome 3H in barley. However, the chromosome scale of the comparative maps presented provides new insights into grass genome organization. The disruptions of the Ae. tauschii-rice and Ae. tauschii-Brachypodium syntenies were identical. We observed chromosomal rearrangements between Ae. tauschii and barley. The comparison of Ae. tauschii physical and genetic maps showed that the recombination rate across the region dropped from 2.19 cM/Mb in the distal region to 0.09 cM/Mb in the proximal region. The size of the gaps between contigs was evaluated by comparing the recombination rate along the map with the local recombination rates calculated on single contigs. Conclusions The physical map reported here is the first physical map using fingerprinting of a complete

  6. Modernity, Rationality and Constitutional Law in Muslim-Majority Countries

    DEFF Research Database (Denmark)

    Abat Ninet, Antoni

    Are Islamic law, human rights and constitutionalism compatible? In answering this question, this paper first discusses the concept of modernity (understood in terms of rationality and standardization), analysing its abrupt implementation in the MENA countries and the role that the first modern...... constitutions played in institutionalising a new sort of dominion in the newly established states. Against this background, the paper discusses the relationship between constitutionalism and Shari’a law, presenting this as a clash between two competing normative visions that are conceptually difficult...... to reconcile and which each claim exclusivity and hierarchical superiority. The paper advocates for a deconstruction of the ideas of human rights and constitutionalism in order to allow for the incorporation of elements of Muslim traditions, thus challenging the understanding of human rights...

  7. A unified viscoplasticity constitutive model based on irreversible thermodynamics

    Institute of Scientific and Technical Information of China (English)

    LIU ChangChun; LV HeXiang; GUAN Ping

    2008-01-01

    A unified viscoplasticity constitutive model for metal materials is developed within the framework of irreversible thermodynamics, and an expression for the Helmholtz free energy function involving the parameters reflecting kinematic hardening and isotropic hardening is given. At the same time a non-associated flow potential function including the corresponding state variables is also given, from which the flow equation and the evolution equations of the internal state variables are derived. Thus, a general theoretical framework constructing a unified viscoplasticity con-stitutive model is given. Compared with the typical unified viscoplasticity constitu-tive models, the presented model evidently satisfies the irreversible thermody-namics laws. Moreover, this method not only provides a new theoretical foundation for further development of the unified viscoplasticity constitutive model, but also gives a new theoretical framework for the stress-strain analysis of more materials.

  8. Romanian Presidential Institution in the Present Constitutional Framework

    Directory of Open Access Journals (Sweden)

    Cristian Ionescu

    2012-12-01

    Full Text Available Romanian semi-presidential system, and the Republic President`s role within government process represent a very actual theme for political sciences and both for constitutional doctrine. Constitution adopted in 1991 and revised in 2003, had consecrated the model of semi-presidentialism but did not manage to find for the President of the Republic the suitable prerogatives to his constitutional role. President of Romania has attributions of a president in a parliamentary republic but often the will and power claims of presidents exceeded their constitutional role. In this way, the President step in disputes both with Parliament and Government. In this article, the author focuses on the institutional relationships between President, Parliament and Prime Minister and the Presidential legitimacy, also.

  9. GENERAL EXPRESSIONS OF CONSTITUTIVE EQUATIONS FOR ISOTROPIC ELASTIC DAMAGED MATERIALS

    Institute of Scientific and Technical Information of China (English)

    唐雪松; 蒋持平; 郑健龙

    2001-01-01

    The general expressions of constitutive equations for isotropic elastic damaged materials were derived directly from the basic law of irreversible thermodynamics. The limitations of the classical damage constitutive equation based on the well-known strain equivalence hypothesis were overcome. The relationships between the two elastic isotropic damage models(i. e. single and double scalar damage models)were revealed. When a single scalar damage variable defined according to the microscopic geometry of a damaged material is used to describle the isotropic damage state, the constitutive equations contain two "damage effect functions", which describe the different influences of damage on the two independent elastic constants. The classical damage constitutive equation based on the strain equivalence hypothesis is only the first-order approximation of the general expression.It may be unduly simplified and may fail to describe satisfactorily the damage phenomena of practical materials.

  10. DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection.

    Science.gov (United States)

    Clima, Lilia; Peptanariu, Dragos; Pinteala, Mariana; Salic, Adrian; Barboiu, Mihail

    2015-12-25

    Dynamic constitutional frameworks, based on squalene, PEG and PEI components, reversibly connected to core centers, allow the efficient identification of adaptive vectors for good DNA transfection efficiency and are well tolerated by mammalian cells.

  11. A unified viscoplasticity constitutive model based on irreversible thermodynamics

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A unified viscoplasticity constitutive model for metal materials is developed within the framework of irreversible thermodynamics, and an expression for the Helmholtz free energy function involving the parameters reflecting kinematic hardening and isotropic hardening is given. At the same time a non-associated flow potential function including the corresponding state variables is also given, from which the flow equation and the evolution equations of the internal state variables are derived. Thus, a general theoretical framework constructing a unified viscoplasticity constitutive model is given. Compared with the typical unified viscoplasticity constitutive models, the presented model evidently satisfies the irreversible thermodynamics laws. Moreover, this method not only provides a new theoretical foundation for further development of the unified viscoplasticity constitutive model, but also gives a new theoretical framework for the stress-strain analysis of more materials.

  12. Constitution. Signed and delivered--the rules in writing.

    Science.gov (United States)

    Walshe, Kieran

    2008-07-24

    The proposal tucked away in the Darzi report for an NHS constitution could be one of the most historic elements of the next stage review, limiting the health secretary's power and guaranteeing patient rights.

  13. NATIONAL ENVIRONMENTAL LABORATORY ACCREDITATION CONFERENCE (NELAC): CONSTITUTION, BYLAWS, AND STANDARDS

    Science.gov (United States)

    The principles and operating procedures for the National Environmental Laboratory Accreditation Conference (NELAC) are contained in the NELAC Constitution and Bylaws. The major portion of this document (standards) contains detailed requirements for accrediting environmental labo...

  14. Constitutive Equation of Superalloy In718 in Hammer Forging Process

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A constitutive equation reflecting the flow behavior ofSuperalloy In718 during the counter-blow hammer forging process was developed in terms of the relationship of flow stress and hot-deformation parameters, such as strain, strain rate, and deformation temperature. A new simplified approach for the complex multi-pass stress-strain curves has been attempted. The simulation curves calculated by constitutive equation are consistent with the experimental data.

  15. Beyond the future: Fortune telling as constituted in the media

    OpenAIRE

    Lyon, Taryn

    2011-01-01

    This paper utilizes discourse analysis (DA) to research how fortune telling is constituted in the news media. As current paranormal belief research is largely inconclusive (Wiseman & Watt, 2006), this paper addresses the problem of constitution as outlined by discursive psychologists (Potter & Wetherell, 1987) and seeks to better understand how paranormal objects, using fortune telling as an example, are constructed. After analyzing forty-three news articles regarding fortune telling, this pa...

  16. Structure and dynamics of a constitutively active neurotensin receptor

    Energy Technology Data Exchange (ETDEWEB)

    Krumm, Brian E. [National Inst. of Health (NIH), Rockville, MD (United States). National Inst. of Neurological Disorders and Stroke, Dept. of Health and Human Services; Lee, Sangbae [Beckman Research Inst. of the City of Hope, Duarte, CA (United States). Dept. of Molecular Immunology; Bhattacharya, Supriyo [Beckman Research Inst. of the City of Hope, Duarte, CA (United States). Dept. of Molecular Immunology; Botos, Istvan [National Inst. of Health (NIH), Bethesda, MD (United States). National Inst. of Diabetes and; White, Courtney F. [National Inst. of Health (NIH), Rockville, MD (United States). National Inst. of Neurological Disorders and Stroke, Dept. of Health and Human Services; Du, Haijuan [National Inst. of Health (NIH), Rockville, MD (United States). National Inst. of Neurological Disorders and Stroke, Dept. of Health and Human Services; Vaidehi, Nagarajan [Beckman Research Inst. of the City of Hope, Duarte, CA (United States). Dept. of Molecular Immunology; Grisshammer, Reinhard [National Inst. of Health (NIH), Rockville, MD (United States). National Inst. of Neurological Disorders and Stroke, Dept. of Health and Human Services

    2016-12-07

    Many G protein-coupled receptors show constitutive activity, resulting in the production of a second messenger in the absence of an agonist; and naturally occurring constitutively active mutations in receptors have been implicated in diseases. To gain insight into mechanistic aspects of constitutive activity, we report here the 3.3 Å crystal structure of a constitutively active, agonist-bound neurotensin receptor (NTSR1) and molecular dynamics simulations of agonist-occupied and ligand-free receptor. Comparison with the structure of a NTSR1 variant that has little constitutive activity reveals uncoupling of the ligand-binding domain from conserved connector residues, that effect conformational changes during GPCR activation. Furthermore, molecular dynamics simulations show strong contacts between connector residue side chains and increased flexibility at the intracellular receptor face as features that coincide with robust signalling in cells. The loss of correlation between the binding pocket and conserved connector residues, combined with altered receptor dynamics, possibly explains the reduced neurotensin efficacy in the constitutively active NTSR1 and a facilitated initial engagement with G protein in the absence of agonist.

  17. A macro-mechanical constitutive model for shape memory polymer

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    It is of theoretical and engineering interest to establish a macro-mechanical constitutive model of the shape memory polymer (SMP), which includes the mechanical constitutive equation and the material parameter function, from the viewpoint of practical application. In this paper, a new three-dimensional macro-mechanical constitutive equation, which describes the mechanical behaviors associated with the shape memory effect of SMP, is developed based on solid mechanics and the viscoelasticity theorem. According to the results of the DMA test, a new material parameter function is established to express the relationship of the material parameters and temperature during the glass transition of SMP. The new macro-mechanical constitutive equation and material parameter function are used to numerically simulate the process producing the shape memory effect of SMP, which includes deforming at high temperature, stress freezing, unloading at low temperature and shape recovery. They are also used to investigate and analyze the influences of loading rate and temperature change rate on the thermo-mechanical behaviors of SMP. The numerical results and the comparisons with Zhou’s material parameter function and Tobushi’s mechanical constitutive equation illustrate that the proposed three-dimensional macro-mechanical constitutive model can effectively predict the thermo-mechanical behaviors of SMP under the state of complex stress.

  18. Relationships among Constitution, Stress, and Discomfort in the First Trimester

    Directory of Open Access Journals (Sweden)

    Hsiao-Ling Wang

    2012-01-01

    trimester of pregnancy. We adopted a descriptive and correlational research design and collected data from 261 pregnant women during their first trimester in southern Taiwan using structured questionnaires. Results showed that (1 stress was significantly and positively correlated with Yang-Xu, Yin-Xu, and Tan-Shi-Yu-Zhi constitutions, respectively; (2 Yin-Xu and Tan-Shi-Yu-Zhi constitutions had significant correlations with all symptoms of discomfort, while Yang-Xu had significant correlations with all symptoms of discomfort except for “running nose”; (3 Tan-Shi-Yu-Zhi constitution and stress were two indicators for “fatigue”; Tan-Shi-Yu-Zhi was the indicator for “nausea”; Yang-Xu and Yin-Xu were indicators for “frequent urination.” Our findings also indicate that stress level affects constitutional changes and that stress and constitutional change affect the incidence of discomfort. This research can help healthcare professionals observe these discomforts and provide individualized care for pregnant women, to nurture pregnant women into neutral-type constitution, minimize their levels of discomfort, and promote the health of the fetus and the mother.

  19. Constitutional Principles of State Control in the Republic of Armenia

    Directory of Open Access Journals (Sweden)

    Gabriel K. Balayan

    2015-12-01

    Full Text Available In the present article some of the provision of the RA Constitution’s basic principles of state control, which, in my opinion, should be guided by regulatory authorities during the inspection are discussed. These principles are considered by the author as the basis of the constitutionality of state control. Some of the control principles are divided by the author into positive and negative. Positive defines the principles that provide the freedom of action of man and citizen. Negative same principles are for government agencies, since they restrict their activities. A separate analysis is subject to the presidency on the basis of the principle of separation and balance of powers. In conclusion, author concludes that, based on the interpretation of the constitutional principles discussed, the term "law" applies only to natural and legal persons on the other hand can not be used as an analogue of the terms "authority" and "authority." According to the author, the fundamental constitutional principles of state control are expressed formally in a single system as defined in the first chapter of the Constitution of the Republic of Armenia. Compliance and reform of constitutional principles provide the synergy and the constitutionality of the process of governance.

  20. Competition is constitutional: Four fallacies in the argument that transmission access constitutes a taking

    Energy Technology Data Exchange (ETDEWEB)

    Schotland, S.D. [Gottlieb, Steen & Hamilton, Washington, DC (United States)

    1996-11-01

    New transmission regulations may cause a change in property value or property access, however, this alone does not constitute a regulatory taking. In an industry with a long history of regulation and some degree of shared transmission access, the utilities are going to be hard pressed to show that recent open access mandates are in violation of the Takings Clause of the Fifth Amendment. In a recent article, John Rowe and Paige Graening of the NEES Companies argued that transmission access is the twentieth century equivalent of {open_quotes}piracy{close_quotes} - forcing utilities to provide transmission access to third parties violates the Taking Clause of the Fifth Amendment. The authors stated that transmission access represents a permanent physical invasion of property - which is unconstitutional without {open_quotes}just compensation.{close_quotes} The same arguments have been raised by Michigan utilities in a pending court challenge to the retail wheeling experiment ordered by the Michigan Public Service Commission. Rowe and Graening complain that {open_quotes}under the Jolly Roger of open competition{close_quotes} regulators will limit utilities to {open_quotes}mere embedded costs,{close_quotes} thereby committing an act of {open_quotes}piracy.{close_quotes} Contrary to Rowe and Graening`s claim, the flag of competition is better represented by the Stars and Stripes, since orders to provide transmission access at the cost of service do not result in a regulatory taking. Four fallacies led NEES down the gangplank: (1) The authors argued that reductions in the value of an investment are necessarily takings. Regulatory impairment of property value is a fact of life. (2) Contrary to NEES, transmission access does not effect a permanent physical invasion of property. (3) NEES claimed that transmission access defeats reasonable investment expectations. (4) NEES relied on case law that affords utilities the opportunity to realize a profit.

  1. The Initial Study of Theme Archetype in Our Ancestors%《我们的祖先》中的主题原型初探

    Institute of Scientific and Technical Information of China (English)

    杨晓莲; 昝佳佳

    2011-01-01

    Italo Calvino is a famous contemporary Italian writer. Our Ancestors is one of his masterpieces. This paper tries to select the archetypal criticism to excavate the theme archetype in the novel. Through the analysis and interpretation of the binary opposi%伊塔洛·卡尔维诺是意大利当代著名作家,《我们的祖先》是其代表作之一。文章试图从神话原型理论入手,来探讨《我们的祖先》所隐含的主题原型。通过对小说所体现的二元对立原型、死亡与复活原型、追寻原型的分析和解读,实现对文本更深入的理解,从而挖掘出小说更深刻的内涵与价值。

  2. Multiple origins of Heliozoa from flagellate ancestors: New cryptist subphylum Corbihelia, superclass Corbistoma, and monophyly of Haptista, Cryptista, Hacrobia and Chromista.

    Science.gov (United States)

    Cavalier-Smith, Thomas; Chao, Ema E; Lewis, Rhodri

    2015-12-01

    Heliozoan protists have radiating cell projections (axopodia) supported by microtubular axonemes nucleated by the centrosome and bearing granule-like extrusomes for catching prey. To clarify previously confused heliozoan phylogeny we sequenced partial transcriptomes of two tiny naked heliozoa, the endohelean Microheliella maris and centrohelid Oxnerella marina, and the cercozoan pseudoheliozoan Minimassisteria diva. Phylogenetic analysis of 187 genes confirms that all are chromists; but centrohelids (microtubules arranged as hexagons and triangles) are not sisters to Endohelea having axonemes in transnuclear cytoplasmic channels (triangular or square microtubular arrays). Centrohelids are strongly sister to haptophytes (together phylum Haptista); we explain the common origins of their axopodia and haptonema. Microheliella is sister to new superclass Corbistoma (zooflagellate Telonemea and Picomonadea, with asymmetric microfilamentous pharyngeal basket), showing that these axopodial protists evolved independently from zooflagellate ancestors. We group Corbistoma and Endohelea as new cryptist subphylum Corbihelia with dense fibrillar interorganellar connections; endohelean axopodia and Telonema cortex are ultrastructurally related. Differently sampled trees clarify why corticate multigene eukaryote phylogeny is problematic: long-branch artefacts probably distort deep multigene phylogeny of corticates (Plantae, Chromista); basal radiations may be contradictorily reconstructed because of their extreme closeness and the Bayesian star-tree paradox. Haptista and Hacrobia are holophyletic, and Chromista probably are.

  3. Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s.

    Science.gov (United States)

    Carbone, Michele; Flores, Erin G; Emi, Mitsuru; Johnson, Todd A; Tsunoda, Tatsuhiko; Behner, Dusty; Hoffman, Harriet; Hesdorffer, Mary; Nasu, Masaki; Napolitano, Andrea; Powers, Amy; Minaai, Michael; Baumann, Francine; Bryant-Greenwood, Peter; Lauk, Olivia; Kirschner, Michaela B; Weder, Walter; Opitz, Isabelle; Pass, Harvey I; Gaudino, Giovanni; Pastorino, Sandra; Yang, Haining

    2015-12-01

    We recently discovered an inherited cancer syndrome caused by BRCA1-Associated Protein 1 (BAP1) germline mutations, with high incidence of mesothelioma, uveal melanoma and other cancers and very high penetrance by age 55. To identify families with the BAP1 cancer syndrome, we screened patients with family histories of multiple mesotheliomas and melanomas and/or multiple cancers. We identified four families that shared an identical BAP1 mutation: they lived across the US and did not appear to be related. By combining family histories, molecular genetics, and genealogical approaches, we uncovered a BAP1 cancer syndrome kindred of ~80,000 descendants with a core of 106 individuals, whose members descend from a couple born in Germany in the early 1700s who immigrated to North America. Their descendants spread throughout the country with mutation carriers affected by multiple malignancies. Our data show that, once a proband is identified, extended analyses of these kindreds, using genomic and genealogical studies to identify the most recent common ancestor, allow investigators to uncover additional branches of the family that may carry BAP1 mutations. Using this knowledge, we have identified new branches of this family carrying BAP1 mutations. We have also implemented early-detection strategies that help identify cancers at early-stage, when they can be cured (melanomas) or are more susceptible to therapy (MM and other malignancies).

  4. Floral homeotic genes were recruited from homologous MADS-box genes preexisting in the common ancestor of ferns and seed plants.

    Science.gov (United States)

    Münster, T; Pahnke, J; Di Rosa, A; Kim, J T; Martin, W; Saedler, H; Theissen, G

    1997-03-18

    Flowers sensu lato are short, specialized axes bearing closely aggregated sporophylls. They are typical for seed plants (spermatophytes) and are prominent in flowering plants sensu stricto (angiosperms), where they often comprise an attractive perianth. There is evidence that spermatophytes evolved from gymnosperm-like plants with a fern-like mode of reproduction called progymnosperms. It seems plausible, therefore, that the stamens/carpels and pollen sacs/nucelli of spermatophytes are homologous to fern sporophylls and sporangia, respectively. However, the exact mode and molecular basis of early seed and flower evolution is not yet known. Comparing flower developmental control genes to their homologs from lower plants that do not flower may help to clarify the issue. We have isolated and characterized MADS-box genes expressed in gametophytes and sporophytes of the fern Ceratopteris. The data indicate that at least two different MADS-box genes homologous to floral homeotic genes existed in the last common ancestor of contemporary vascular plants, some descendants of which underwent multiple duplications and diversifications and were recruited into novel developmental networks during the evolution of floral organs.

  5. Reconstruction of the most recent common ancestor sequences of SARS-Cov S gene and detection of adaptive evolution in the spike protein

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yuan; ZHENG Nan; HAO Pei; ZHONG Yang

    2004-01-01

    @@ The genome organization and expression strategy of severe acute respiratory syndrome coronavirus (SARSCoV) have been described extensivelyl1- 10]. As a structural glycoprotein on the virion surface, the spike protein is responsible for binding to host cellular receptors and for the fusion between the viral envelope and the cellular membrane. It also induces neutralizing antibodies in the host and mediates cellular immunity[11]. Previous studies suggested that amino acid replacements in the spike protein could dramatically alter the pathogenesis and virulence of some coronaviruses[11]. It is therefore reasonable to test the hypothesis that radical amino acid replacements in the spike protein, favored by environmental selective pressure during the process of SARS-CoV interspecific transmission[10], might make this pathogen adapt to a new host. In this study, we investigated a total of 108complete sequences of the SARS-CoV S gene from GenBank (until March 23, 2004). After omission of those records containing frame-shift mutations or low quality sequences, e.g. ZJ01, and selection of one sequence for identical records, an alignment of 42 sequences was obtained using the program Clustal-X[13]. Then, we reconstructed the most recent common ancestor (MRCA) sequences of the SARS-CoV S gene and detected the adaptive evolution in the spike protein.

  6. Mitochondrial genome of the homoscleromorph Oscarella carmela (Porifera, Demospongiae) reveals unexpected complexity in the common ancestor of sponges and other animals.

    Science.gov (United States)

    Wang, Xiujuan; Lavrov, Dennis V

    2007-02-01

    Homoscleromorpha is a small group in the phylum Porifera (Sponges) characterized by several morphological features (basement membrane, acrosomes in spermatozoa, and cross-striated rootlets of the flagellar basal apparatus) shared with eumetazoan animals but not found in most other sponges. To clarify the phylogenetic position of this group, we determined and analyzed the complete mitochondrial DNA (mtDNA) sequence of the homoscleromorph sponge Oscarella carmela (Porifera, Demospongiae). O. carmela mtDNA is 20,327 bp and contains the largest complement of genes reported for animal mtDNA, including a putative gene for the C subunit of the twin-arginine translocase (tatC) that has never been found in animal mtDNA. The genes in O. carmela mtDNA are arranged in 2 clusters with opposite transcriptional orientations, a gene arrangement reminiscent of those in several cnidarian mtDNAs but unlike those reported in sponges. At the same time, phylogenetic analyses based on concatenated amino acid sequences from 12 mitochondrial (mt) protein genes strongly support the phylogenetic affinity between the Homoscleromorpha and other demosponges. Altogether, our data suggest that homoscleromorphs are demosponges that have retained ancestral features in both mt genome and morphological organization lost in other taxa and that the most recent common ancestor of sponges and other animals was morphologically and genetically more complex than previously thought.

  7. CONSTITUTIVE RELATION OF UNSATURATED SOIL BY USE OF THE MIXTURE THEORY(Ⅰ)-NONLINEAR CONSTITUTIVE EQUATIONS AND FIELD EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    黄义; 张引科

    2003-01-01

    The nonlinear constitutive equations and field equations of unsaturated soils were cons tructed on the basis of mixture theory. The soils were treated as the mixture composed of three constituents. First, from the researches of soil mechanics, some basic assumptions about the unsaturated soil mixture were made, and the entropy inequality of unsaturated soil mixture was derived. Then, with the common method usually used to deal with the constitutive problems in mixture theory, the nonlinear constitutive equations were obtained. Finally, putting the constitutive equations of constituents into the balance equations of momentum, the nonlinear field equations of constituents were set up. The balance equation of energy of unsaturated soil was also given, and thus the complete equations for solving the thermodynamic process of unsaturated soil was formed.

  8. THE RIGHTS OF A PROTECTED LESSEE FROM THE VIEWPOINT OF THE CONSTITUTIONAL COURT

    Directory of Open Access Journals (Sweden)

    Marko Babic

    2013-12-01

    Full Text Available Regulating relations in the sphere of housing for their compliance with the Constitution, the legislator has, by the Rent Act, replaced tenant’s right of tenancy, under certain conditions, to lease. Since the alignment of housing legislation implemented during the transition period of transformation of social property and privatization, the legislator, for the owners of apartments, had kept the burden of restrictions on their property rights, the burden of protected tenants, as (inevitable effect to protect vested rights (based on valid legal grounds on the apartment that is not their property. The enforcement of this legal regulation had not demanded that the owners of these apartments suffer greater restrictions on their ownership than the limitations that already existed, and which consisted in impossibility to live in that apartment. However, the Rent Act in Article 19 provides for situations in which the lessor (landlord may cancel the lease to lessee (the former person entitled to tenancy rights. Nevertheless, except for reasons of Article 19 of Rent Act, landlord may terminate the lease if he intends to settle in the apartment wether alone or with his descendants, parents or persons under special regulations to support (Article 21 and 40 of the Rent Act. Regarding to their extreme sensitivity that emerged in implementing the law on real life (dis advantages of addressees, Article 21 Paragraph 2 and Article 40 paragraphs 1 and 2 were before the Constitutional Court in the proceedings initiated in order to assess their conformity with the Constitution. Because of established breach of Articles 3, 14 § 2, 48 paragraph 1 and 50 paragraph 1 of the Constitution, Croatian Constitutional Court in decision and ruling UI-762/1996 abolished Article 21 Paragraph 2 and Article 40 § of Rent Act. In pronouncement of mentioned decision is determined that abolished Article 21 Paragraph 2 and Article 40 Paragraph 2 of Rent Act expire until six months

  9. Some ancestors of contraction analysis

    DEFF Research Database (Denmark)

    Jouffroy, Jerome

    2005-01-01

    Contraction analysis is a recent tool for analyzing the convergence behavior of nonlinear systems in state-space form (see Lohmiller and Slotine [16] for the main reference). However, it seems that earlier results derived by mathematicians in the 1950s closely match some of the results of contrac...... of contraction analysis. In this paper, we review and place into perspective some references of this era, and relate them with contraction....

  10. Evaluation of potential crushed-salt constitutive models

    Energy Technology Data Exchange (ETDEWEB)

    Callahan, G.D.; Loken, M.C.; Sambeek, L.L. Van; Chen, R.; Pfeifle, T.W.; Nieland, J.D. [RE/SPEC Inc., Rapid City, SD (United States); Hansen, F.D. [Sandia National Labs., Albuquerque, NM (United States). Repository Isolation Systems Dept.

    1995-12-01

    Constitutive models describing the deformation of crushed salt are presented in this report. Ten constitutive models with potential to describe the phenomenological and micromechanical processes for crushed salt were selected from a literature search. Three of these ten constitutive models, termed Sjaardema-Krieg, Zeuch, and Spiers models, were adopted as candidate constitutive models. The candidate constitutive models were generalized in a consistent manner to three-dimensional states of stress and modified to include the effects of temperature, grain size, and moisture content. A database including hydrostatic consolidation and shear consolidation tests conducted on Waste Isolation Pilot Plant and southeastern New Mexico salt was used to determine material parameters for the candidate constitutive models. Nonlinear least-squares model fitting to data from the hydrostatic consolidation tests, the shear consolidation tests, and a combination of the shear and hydrostatic tests produces three sets of material parameter values for the candidate models. The change in material parameter values from test group to test group indicates the empirical nature of the models. To evaluate the predictive capability of the candidate models, each parameter value set was used to predict each of the tests in the database. Based on the fitting statistics and the ability of the models to predict the test data, the Spiers model appeared to perform slightly better than the other two candidate models. The work reported here is a first-of-its kind evaluation of constitutive models for reconsolidation of crushed salt. Questions remain to be answered. Deficiencies in models and databases are identified and recommendations for future work are made. 85 refs.

  11. The Constitutionality of a Biological Father's Recognition as a Parent

    Directory of Open Access Journals (Sweden)

    A Louw

    2010-12-01

    Full Text Available Despite the increased recognition afforded to biological fathers as legal parents, the Children's Act 38 of 2005 still does not treat fathers on the same basis as mothers as far as the automatic allocation of parental responsibilities and rights is concerned. This article investigates the constitutionality of the differential treatment of fathers in this respect, given South Africa's international obligations, especially in terms of the United Nations Convention on the Rights of the Child, to ensure that both parents have common responsibilities for the upbringing of their child. After a brief consideration of the constitutionality of the mother's position as parent, the constitutionality of the father's position is investigated, firstly, with reference to Section 9 of the Constitution and the question of whether the differentiation between mothers and fathers as far as the allocation of parental responsibilities and rights is concerned, amounts to unfair discrimination. The inquiry also considers whether the differentiation between committed fathers (that is, those who have shown the necessary commitment in terms of Sections 20 and 21 of the Children's Act to acquire parental responsibilities and rights and uncommitted fathers may amount to discrimination on an unspecified ground. Since the limitation of the father's rights to equality may be justifiable, the outcomes of both inquiries are shown to be inconclusive. Finally, the legal position of the father is considered in relation to the child's constitutional rights – the rights to parental care and the right of the child to the paramountcy of its interests embodied in Section 28 of the Constitution. While there appears to be some justification for the limitation of the child's right to committed paternal care, it is submitted that an equalisation of the legal position of mothers and fathers as far as the automatic acquisition of parental responsibilities and rights is concerned, is not

  12. Deviatoric constitutive model: domain of strain rate validity

    Energy Technology Data Exchange (ETDEWEB)

    Zocher, Marvin A [Los Alamos National Laboratory

    2009-01-01

    A case is made for using an enhanced methodology in determining the parameters that appear in a deviatoric constitutive model. Predictability rests on our ability to solve a properly posed initial boundary value problem (IBVP), which incorporates an accurate reflection of material constitutive behavior. That reflection is provided through the constitutive model. Moreover, the constitutive model is required for mathematical closure of the IBVP. Common practice in the shock physics community is to divide the Cauchy tensor into spherical and deviatoric parts, and to develop separate models for spherical and deviatoric constitutive response. Our focus shall be on the Cauchy deviator and deviatoric constitutive behavior. Discussions related to the spherical part of the Cauchy tensor are reserved for another time. A number of deviatoric constitutive models have been developed for utilization in the solution of IBVPs that are of interest to those working in the field of shock physics, e.g. All of these models are phenomenological and contain a number of parameters that must be determined in light of experimental data. The methodology employed in determining these parameters dictates the loading regime over which the model can be expected to be accurate. The focus of this paper is the methodology employed in determining model parameters and the consequences of that methodology as it relates to the domain of strain rate validity. We shall begin by describing the methodology that is typically employed. We shall discuss limitations imposed upon predictive capability by the typically employed methodology. We shall propose a modification to the typically employed methodology that significantly extends the domain of strain rate validity.

  13. The capability to synthesize phytochelatins and the presence of constitutive and functional phytochelatin synthases are ancestral (plesiomorphic) characters for basal land plants.

    Science.gov (United States)

    Petraglia, Alessandro; De Benedictis, Maria; Degola, Francesca; Pastore, Giovanni; Calcagno, Margherita; Ruotolo, Roberta; Mengoni, Alessio; Sanità di Toppi, Luigi

    2014-03-01

    Bryophytes, a paraphyletic group which includes liverworts, mosses, and hornworts, have been stated as land plants that under metal stress (particularly cadmium) do not synthesize metal-binding peptides such as phytochelatins. Moreover, very little information is available to date regarding phytochelatin synthesis in charophytes, postulated to be the direct ancestors of land plants, or in lycophytes, namely very basal tracheophytes. In this study, it was hypothesized that basal land plants and charophytes have the capability to produce phytochelatins and possess constitutive and functional phytochelatin synthases. To verify this hypothesis, twelve bryophyte species (six liverworts, four mosses, and two hornworts), three charophytes, and two lycophyte species were exposed to 0-36 μM cadmium for 72 h, and then assayed for: (i) glutathione and phytochelatin quali-quantitative content by HPLC and mass spectrometry; (ii) the presence of putative phytochelatin synthases by western blotting; and (iii) in vitro activity of phytochelatin synthases. Of all the species tested, ten produced phytochelatins in vivo, while the other seven did not. The presence of a constitutively expressed and functional phytochelatin synthase was demonstrated in all the bryophyte lineages and in the lycophyte Selaginella denticulata, but not in the charophytes. Hence, current knowledge according to phytochelatins have been stated as being absent in bryophytes was therefore confuted by this work. It is argued that the capability to synthesize phytochelatins, as well as the presence of active phytochelatin synthases, are ancestral (plesiomorphic) characters for basal land plants.

  14. Wildlife, exotic pets, and emerging zoonoses.

    Science.gov (United States)

    Chomel, Bruno B; Belotto, Albino; Meslin, François-Xavier

    2007-01-01

    Most emerging infectious diseases are zoonotic; wildlife constitutes a large and often unknown reservoir. Wildlife can also be a source for reemergence of previously controlled zoonoses. Although the discovery of such zoonoses is often related to better diagnostic tools, the leading causes of their emergence are human behavior and modifications to natural habitats (expansion of human populations and their encroachment on wildlife habitat), changes in agricultural practices, and globalization of trade. However, other factors include wildlife trade and translocation, live animal and bushmeat markets, consumption of exotic foods, development of ecotourism, access to petting zoos, and ownership of exotic pets. To reduce risk for emerging zoonoses, the public should be educated about the risks associated with wildlife, bushmeat, and exotic pet trades; and proper surveillance systems should be implemented.

  15. Constitutive sensitivity of the oscillatory behaviour of hyperelastic cylindrical shells

    Science.gov (United States)

    Aranda-Iglesias, D.; Vadillo, G.; Rodríguez-Martínez, J. A.

    2015-12-01

    Free and forced nonlinear radial oscillations of a thick-walled cylindrical shell are investigated. The shell material is taken to be incompressible and isotropic within the framework of finite nonlinear elasticity. In comparison with previous seminal works dealing with the dynamic behaviour of hyperelastic cylindrical tubes, in this paper we have developed a broader analysis on the constitutive sensitivity of the oscillatory response of the shell. In this regard, our investigation is inspired by the recent works of Bucchi and Hearn (2013) [28,29], who carried out a constitutive sensitivity analysis of similar problem with hyperelastic cylindrical membranes subjected to static inflation. In the present paper we consider two different Helmholtz free-energy functions to describe the material behaviour: Mooney-Rivlin and Yeoh constitutive models. We carry out a systematic comparison of the results obtained by application of both constitutive models, paying specific attention to the critical initial and loading conditions which preclude the oscillatory response of the cylindrical tube. It has been found that these critical conditions are strongly dependent on the specific constitutive model selected, even though both Helmholtz free-energy functions were calibrated using the same experimental data.

  16. Coupled elasto-plasticity damage constitutive models for concrete

    Institute of Scientific and Technical Information of China (English)

    Qiang XU; Jian-yun CHEN; Jing LI; Gang XU

    2013-01-01

    The paper is to design and construct a coupled elasto-plasticity damage constitutive model for concrete.Based on the energy dissipation principle,the Hsieh-Ting-Chen four-parameter yield function is used.The model can reflect different strength characteristics of concrete in tension and compression,and reduce the limitation and lacuna of the traditional damage constitutive models for concrete.Furthermore,numerical test for concrete stress-strain relation under uniaxial tension and compression is given.Moreover,the damage process of concrete gravity dam is calculated and analyzed in seismic load.Compared with other damage constitutive models,the proposed model contains only one unknown parameter and the other parameters can be found in the Hsieh-Ting-Chen four-parameter yield function.The same damage evolution law,which is used for tension and compression,is good for determining stress-strain constitutive and damage characteristics in complex stress state.This coupled damage constitutive models can be applied in analyzing damage of concrete gravity dam and arch dam.

  17. Randomized clinical trials of constitutional acupuncture: a systematic review.

    Science.gov (United States)

    Lee, Myeong Soo; Shin, Byung-Cheul; Choi, Sun-Mi; Kim, Jong Yeol

    2009-09-01

    The aim of this systematic review is to compile and critically evaluate the evidence from randomized clinical trials (RCTs) for the effectiveness of acupuncture using constitutional medicine compared to standard acupuncture. Ten databases were searched through to December 2008 without language restrictions. We also hand-searched nine Korean journals of oriental medicine. We included prospective RCTs of any form of acupuncture with or without electrical stimulation. The included trials had to investigate constitutional medicine. There were no restrictions on population characteristics. Forty-one relevant studies were identified, and three RCTs were included. The methodological quality of the trials was variable. One RCT found Sasang constitutional acupuncture to be superior to standard acupuncture in terms of the Unified PD Rating Scale and freezing gate in Parkinson's disease (PD). Another two RCTs reported favorable effects of eight constitutional acupuncture on pain reduction in patients with herniated nucleus pulposi and knee osteoarthritis. Meta-analysis demonstrated positive results for eight constitutional acupuncture compared to standard acupuncture on pain reduction (weighted mean difference: 10 cm VAS, 1.69, 95% CI 0.85-2.54, P acupuncture in treating pain conditions compared to standard acupuncture. However, the total number of RCTs and the total sample size included in our analysis were too small to draw definite conclusions. Future RCTs should assess larger patient samples with longer treatment periods and appropriate controls.

  18. The Icelandic media coverage of the constitutional assembly election

    Directory of Open Access Journals (Sweden)

    Guðbjörg Hildur Kolbeins

    2012-12-01

    Full Text Available On November 27, 2010, the people of Iceland elected 25 individuals to the country’s constitutional assembly. As there were 522 candidates for the 25 seats in the assembly, the media were faced with a new dilemma, i.e. how to ensure impartiality and objectivity in their coverage of the candidates and the subject matter. The present study compares the media coverage of the constitutional assembly election to two other national elections; the general election in the spring of 2009 and the municipal election in the spring of 2010. All news stories in the 13 major print, broadcast and online news outlets in Iceland were coded two weeks prior to each election. The results indicate that the national media almost ignored the constitutional assembly election in comparison to the other elections. There were 632 news stories on the general election, 590 stories on the municipal election but only 165 stories on the constitutional assembly election. The lack of coverage of the candidates for the constitutional assembly seems to reveal that the traditional media, i.e. the print and broadcast media, and the online media did not know how to best serve and inform the public in the democratic process.

  19. Non-linear Constitutive Model for the Oligocarbonate Polyurethane Material

    Institute of Scientific and Technical Information of China (English)

    Marek Pawlikowski

    2014-01-01

    The polyurethane,which was the subject of the constitutive research presented in the paper,was based on oligocarbonate diols Desmophen C2100 produced by Bayer@.The constitutive modelling was performed with a view to applying the material as the inlay of intervertebral disc prostheses.The polyurethane was assumed to be non-linearly viscohyperelastic,isotropic and incompressible.The constitutive equation was derived from the postulated strain energy function.The elastic and rheological constants were identified on the basis of experimental tests,i.e.relaxation tests and monotonic uniaxial tests at two different strain rates,i.e.λ =0.1 min-1 and λ =1.0 min-1.The stiffness tensor was derived and introduced to Abaqus@finite element (FE) software in order to numerically validate the constitutive model.The results of the constants identification and numerical implementation show that the derived constitutive equation is fully adequate to model stress-strain behavior of the polyurethane material.

  20. Perspective of the Human Body in Sasang Constitutional Medicine

    Directory of Open Access Journals (Sweden)

    Junhee Lee

    2009-01-01

    Full Text Available The Sasang constitutional medicine (SCM, a medical tradition originating from Korea, is distinguished from the traditional Chinese medicine in its philosophical background, theoretical development and especially, the fundamental rationale that analyzes the structure and function of the human body within a quadrifocal scheme. In SCM, the structure of the body is comprehended within the Sasang quadrifocal scheme, and the function of the body is understood within the context of the energy-fluid metabolism and the water-food metabolism controlled by the four main organs (lung, spleen, liver and kidney. Also, the concept of Seong-Jeong is used to explain the structural and functional variations between different constitutional types that arise from the constitutional variations in organ system scheme, which are in turn caused by deviations in the constitutional Seong-Jeong. Therefore, understanding the SCM perspective of the human body is essential in order to fully appreciate the advantages of the constitutional typological system (which focuses on individual idiosyncrasies found in SCM.

  1. Perspective of the human body in sasang constitutional medicine.

    Science.gov (United States)

    Lee, Junhee; Jung, Yongjae; Yoo, Junghee; Lee, Euiju; Koh, Byunghee

    2009-09-01

    The Sasang constitutional medicine (SCM), a medical tradition originating from Korea, is distinguished from the traditional Chinese medicine in its philosophical background, theoretical development and especially, the fundamental rationale that analyzes the structure and function of the human body within a quadrifocal scheme. In SCM, the structure of the body is comprehended within the Sasang quadrifocal scheme, and the function of the body is understood within the context of the energy-fluid metabolism and the water-food metabolism controlled by the four main organs (lung, spleen, liver and kidney). Also, the concept of Seong-Jeong is used to explain the structural and functional variations between different constitutional types that arise from the constitutional variations in organ system scheme, which are in turn caused by deviations in the constitutional Seong-Jeong. Therefore, understanding the SCM perspective of the human body is essential in order to fully appreciate the advantages of the constitutional typological system (which focuses on individual idiosyncrasies) found in SCM.

  2. Globalisation of the National Judiciary and the Dutch Constitution

    Directory of Open Access Journals (Sweden)

    Elaine Mak

    2013-03-01

    Full Text Available This article examines the changing practices of the Dutch highest courts, the Hoge Raad and the Afdeling bestuursrechtspraak van de Raad van State, under the influence of globalisation, and the constitutional implications of this development. The increasing intertwinement of legal systems and the increasing possibilities for judges to interact with courts in foreign jurisdictions have stimulated the consideration of foreign legislation and case law in judicial decision-making in individual cases. An empirical study clarifies how the Dutch judges perceive the usefulness of legal comparisons in this context and how foreign law is used in deliberations and judgments. The constitutional implications of the changing practices of the courts are analysed in light of three aspects of the constitutional normative framework for judicial decision-making: the democratic justification of judicial decisions; legal tradition and the nature of cases; and the effectiveness and efficiency of judicial decision-making.

  3. A Review of Constitutive Models for Rubber-Like Materials

    Directory of Open Access Journals (Sweden)

    Aidy Ali

    2010-01-01

    Full Text Available Problem statement: This study reviewed the needs of different constitutive models for rubber like material undergone large elastic deformation. The constitutive models are widely used in Finite Element Analysis (FEA packages for rubber components. Most of the starting point for modeling of various kinds of elastomer is a strain energy function. In order to define the hyperelastic material behavior, stress-strain response is required to determine material parameters in the strain energy potential and also proper selection of rubber elastic material model is the first attention. Conclusion: This review provided a sound basis decision to engineers and manufactures to choose the right model from several constitutive models based on strain energy potential for incompressible and isotropic materials.

  4. New constitutionalism and the social reproduction of caring institutions.

    Science.gov (United States)

    Gill, Stephen; Bakker, Isabella

    2006-01-01

    This essay analyzes neo-liberal economic agreements and legal and political frameworks or what has been called the "new constitutionalism," a governance framework that empowers market forces to reshape economic and social development worldwide. The article highlights some consequences of new constitutionalism for caring institutions specifically, and for what feminists call social reproduction more generally: the biological reproduction of the species; the reproduction of labor power; and the reproduction of social institutions and processes associated with the creation and maintenance of communities. New constitutional governance frameworks fundamentally reshape conditions under which the care of human beings takes place. Caring institutions once governed by enabling professions geared to universal care are now determined increasingly by market values and private forces, and driven directly by the profit motive. This is one of the reasons why neo-liberalism is increasingly contested in both the North and the global South.

  5. Constitutional Challenges of Creating New Local Government Areas in Nigeria

    Directory of Open Access Journals (Sweden)

    Jude Okafor

    2012-08-01

    Full Text Available Local government is purposely established by law to provide grassroots development. In federal states, it is usually created by law of the federating units, and in unitary states it is created by central government. However, since the entrenchment of local government as a third-tier level of government in the 1979/1999 federal constitutions of Nigeria, there have been a lot of difficulties in creating new local governments. This paper examines the dynamics of this structure and the challenges posed to the orderly creation of new local government areas in Nigeria. The paper adopts secondary methods of data collection and analysis. It finds that the conflicting constitutional provisions which vest in the state and federal governments powers to create new local government areas have created many controversies in the polity. It recommends that the creation and statutory finance of local government councils in Nigeria should be expunged from the federal constitution.

  6. A Structural and Grammatical Analysis of the Estonian Constitution

    Directory of Open Access Journals (Sweden)

    Rull Addi

    2016-10-01

    Full Text Available The authors propose a novel quantitative method to analyse the structure of legal texts. The method enables to determine grammatical similarity between legal texts. The authors use the external theory of fundamental rights to separate the text of fundamental rights of the Estonian Constitution into two categories of norms: constitutional rights and restrictions. Grammatical similarity between constitutional rights, restrictions and selected legal acts and case law is measured. The layer of special norms renders the best grammatical similarity with the text of fundamental rights. The same grammatical similarity tests can be replicated to cover other jurisdictions in the future. The research is experimental, but the authors believe that the method can be utilised in fields of computational linguistics and legal text mining, but also in research where legal text structures are analysed for various purposes.

  7. Land Expropriation and Constitutional Protection of Farmers’ Rights

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    One of the reasons for many social tragedies resulted from land expropriation in China is failure of the constitution to bring into play its due functions in standardizing land expropriation power of the government and protecting farmers’ rights.In the existing land expropriation system,government is not only a policy maker of land expropriation,but also a "referee" of dispute over land expropriation.Government’ land expropriation power and land-expropriated farmers’ rights become out of balance.As a result,some local governments do not attach importance to farmers’ rights,making land-expropriated farmers dissatisfied and consequently leading to some social tragedies unfavorable for harmony and stability.To fundamentally settle disputes over land expropriation and realize win-win of farmers’ right and state interest,it should bring into full play functions of the constitution through protecting farmers’ right to participate in land expropriation and establishing constitution evaluation mechanism.

  8. Constitutive mixed mode model for cracks in concrete

    DEFF Research Database (Denmark)

    Jacobsen, J.S.; Poulsen, P.N.; Olesen, J.F.;

    2013-01-01

    The scope of the paper is to set up a constitutive mixed mode model for cracks in concrete. The model is formulated at macro level and includes the most important micro scale effects. An associated plasticity model inspired by the modified Cam clay model is established. The hardening parameters...... is determined from the topographic information and the constitutive model is thereby purely mechanically based. Using the actual topographic description the model is validated against experimental results for mixed mode crack openings....... are based on the standard Mode I tensile softening response and the response for Mode I crushing. The roughness of the crack is included through a topographic description of the crack surface. The constitutive behavior is based on the integration of local contributions. The local mixed mode ratio...

  9. Sasang Constitutional Medicine and Traditional Chinese Medicine: A Comparative Overview

    Directory of Open Access Journals (Sweden)

    Junghee Yoo

    2012-01-01

    Full Text Available Sasang constitutional medicine (SCM is a holistic typological constitution medicine which balances psychological, social, and physical aspects of an individual to achieve wellness and increase longevity. SCM has the qualities of preventative medicine, as it emphasizes daily health management based on constitutionally differentiated regimens and self-cultivation of the mind and body. This review's goal is to establish a fundamental understanding of SCM and to provide a foundation for further study. It compares the similarities and differences of philosophical origins, perspectives on the mind (heart, typological systems, pathology, and therapeutics between SCM and traditional Chinese medicine (TCM. TCM is based on the Taoist view of the universe and humanity. The health and longevity of an individual depends on a harmonious relationship with the universe. On the other hand, SCM is based on the Confucian view of the universe and humanity. SCM focuses on the influence of human affairs on the psyche, physiology, and pathology.

  10. Dynamic compressive behavior and constitutive relations of lanthanum metal

    Institute of Scientific and Technical Information of China (English)

    WANG Huanran; CAI Canyua; CHEN Danian; MA Dongfang; DENG Gaotao

    2012-01-01

    The dynamic compressive behavior and constitutive relations of Lanthanum (La) metal was determined by using the first compression in split Hopkinson pressure bar (SHPB) tests at different strain rates and temperatures.The constitutive relation of La metal determined in a certain range of strains was employed and adjusted in numerically simulating large deformations of La metal spEcimens generated by multi-compression in SHPB tests and recorded by a high-speed camera.The dynamic compressive behavior and constitutive relations of La metal under multiple SHPB tests loading was also revealed.The results of scanning electron microscope (SEM) investigation of the recovered La metal specimens for typical tests showed that there was a variety of deformation microstructures depending on strain rate,temperature and stress state.

  11. Probabilistic estimation of the constitutive parameters of polymers

    Directory of Open Access Journals (Sweden)

    Siviour C.R.

    2012-08-01

    Full Text Available The Mulliken-Boyce constitutive model predicts the dynamic response of crystalline polymers as a function of strain rate and temperature. This paper describes the Mulliken-Boyce model-based estimation of the constitutive parameters in a Bayesian probabilistic framework. Experimental data from dynamic mechanical analysis and dynamic compression of PVC samples over a wide range of strain rates are analyzed. Both experimental uncertainty and natural variations in the material properties are simultaneously considered as independent and joint distributions; the posterior probability distributions are shown and compared with prior estimates of the material constitutive parameters. Additionally, particular statistical distributions are shown to be effective at capturing the rate and temperature dependence of internal phase transitions in DMA data.

  12. A Review of 1982 Constitution Regulations on Political Parties

    Directory of Open Access Journals (Sweden)

    Rıfat KARAKOÇ

    2013-12-01

    Full Text Available Political parties are the vital elements of modern democratic regimes. Today, for a democracy, the existence of more than one political parties and fair and free competition of these parties is a necessity. In Turkey, until 1946, singe party regime has been employed and after this year, Turkey shifted to multi-parties regime, which is required for real democracy. Since 1946, political parties were counted and regulated in 1961 and 1982 constitutions. In this study; the relation between political parties and democracy, the regulations of 1982 constitution on political parties, the amendments in these regulation in time and lastly, the judgments of constitution regarding the closure cases of political parties will be examined.

  13. New inverse method for identification of constitutive parameters

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A new inverse method by coupling iSIGHT and ABAQUS was proposed to determine the constitutive parameters of Al2O3sf/LY12 composite deforming at elevated temperature. It combined the merits of the finite element simulation and optimization technique. The direct model was simulated with finite element code ABAQUS. The inverse problem associated with the identification of the constitutive parameters was expressed as a least square optimization problem. The direct simulation and the parameters optimization were implemented in iSIGHT integrated environment. The aim was to match the output of the direct simulation with the experiment data.The capability of the proposed inverse method was demonstrated through the identification of constitutive parameters of Al2O3sf/LY12composite. The proposed new inverse method is also applicable to other parameters identification which is hardly determined through experiments or direct analytical method.

  14. Randomized Clinical Trials of Constitutional Acupuncture: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Myeong Soo Lee

    2009-01-01

    Full Text Available The aim of this systematic review is to compile and critically evaluate the evidence from randomized clinical trials (RCTs for the effectiveness of acupuncture using constitutional medicine compared to standard acupuncture. Ten databases were searched through to December 2008 without language restrictions. We also hand-searched nine Korean journals of oriental medicine. We included prospective RCTs of any form of acupuncture with or without electrical stimulation. The included trials had to investigate constitutional medicine. There were no restrictions on population characteristics. Forty-one relevant studies were identified, and three RCTs were included. The methodological quality of the trials was variable. One RCT found Sasang constitutional acupuncture to be superior to standard acupuncture in terms of the Unified PD Rating Scale and freezing gate in Parkinson's disease (PD. Another two RCTs reported favorable effects of eight constitutional acupuncture on pain reduction in patients with herniated nucleus pulposi and knee osteoarthritis. Meta-analysis demonstrated positive results for eight constitutional acupuncture compared to standard acupuncture on pain reduction (weighted mean difference: 10 cm VAS, 1.69, 95% CI 0.85–2.54, P < 0.0001; heterogeneity: τ2 = 0.00, Χ2 = 0.00, P = 0.96, I2 = 0%. Our results provide suggestive evidence for the effectiveness of constitutional acupuncture in treating pain conditions compared to standard acupuncture. However, the total number of RCTs and the total sample size included in our analysis were too small to draw definite conclusions. Future RCTs should assess larger patient samples with longer treatment periods and appropriate controls.

  15. The mosaic genome of Anaeromyxobacter dehalogenans strain 2CP-C suggests an aerobic common ancestor to the delta-proteobacteria.

    Directory of Open Access Journals (Sweden)

    Sara H Thomas

    Full Text Available Anaeromyxobacter dehalogenans strain 2CP-C is a versaphilic delta-Proteobacterium distributed throughout many diverse soil and sediment environments. 16S rRNA gene phylogenetic analysis groups A. dehalogenans together with the myxobacteria, which have distinguishing characteristics including strictly aerobic metabolism, sporulation, fruiting body formation, and surface motility. Analysis of the 5.01 Mb strain 2CP-C genome substantiated that this organism is a myxobacterium but shares genotypic traits with the anaerobic majority of the delta-Proteobacteria (i.e., the Desulfuromonadales. Reflective of its respiratory versatility, strain 2CP-C possesses 68 genes coding for putative c-type cytochromes, including one gene with 40 heme binding motifs. Consistent with its relatedness to the myxobacteria, surface motility was observed in strain 2CP-C and multiple types of motility genes are present, including 28 genes for gliding, adventurous (A- motility and 17 genes for type IV pilus-based motility (i.e., social (S- motility that all have homologs in Myxococcus xanthus. Although A. dehalogenans shares many metabolic traits with the anaerobic majority of the delta-Proteobacteria, strain 2CP-C grows under microaerophilic conditions and possesses detoxification systems for reactive oxygen species. Accordingly, two gene clusters coding for NADH dehydrogenase subunits and two cytochrome oxidase gene clusters in strain 2CP-C are similar to those in M. xanthus. Remarkably, strain 2CP-C possesses a third NADH dehydrogenase gene cluster and a cytochrome cbb(3 oxidase gene cluster, apparently acquired through ancient horizontal gene transfer from a strictly anaerobic green sulfur bacterium. The mosaic nature of the A. dehalogenans strain 2CP-C genome suggests that the metabolically versatile, anaerobic members of the delta-Proteobacteria may have descended from aerobic ancestors with complex lifestyles.

  16. A nonlinear viscoelastic constitutive equation - Yield predictions in multiaxial deformations

    Science.gov (United States)

    Shay, R. M., Jr.; Caruthers, J. M.

    1987-01-01

    Yield stress predictions of a nonlinear viscoelastic constitutive equation for amorphous polymer solids have been obtained and are compared with the phenomenological von Mises yield criterion. Linear viscoelasticity theory has been extended to include finite strains and a material timescale that depends on the instantaneous temperature, volume, and pressure. Results are presented for yield and the correct temperature and strain-rate dependence in a variety of multiaxial deformations. The present nonlinear viscoelastic constitutive equation can be formulated in terms of either a Cauchy or second Piola-Kirchhoff stress tensor, and in terms of either atmospheric or hydrostatic pressure.

  17. Constitution and magnetism of iron and its alloys

    CERN Document Server

    Pepperhoff, Werner

    2001-01-01

    Iron played an important role in the development of the industrial society and has not lost any of its significance since today. This book provides the foundations of understanding the physical nature of iron and its alloys. Basics and recent developments concerning its constitution and magnetism are presented as well as its thermal properties. The exceptional role of iron with its wide spectrum of most different technological and physical properties relies on its versatility, its polymorphism of its crystal structure and its magnetism. Therefore it is the aim of the book to link together the constitution and magnetism of iron.

  18. Consistency of certain constitutive relations with quantum electromagnetism

    Energy Technology Data Exchange (ETDEWEB)

    Horsley, S. A. R. [School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, KY16 9SS (United Kingdom)

    2011-12-15

    Recent work by Philbin [New J. Phys. 12, 123008 (2010)] has provided a Lagrangian theory that establishes a general method for the canonical quantization of the electromagnetic field in any dispersive, lossy, linear dielectric. Working from this theory, we extend the Lagrangian description to reciprocal and nonreciprocal magnetoelectric (bianisotropic) media, showing that some versions of the constitutive relations are inconsistent with a real Lagrangian, and hence with quantization. This amounts to a restriction on the magnitude of the magnetoelectric coupling. Moreover, from the point of view of quantization, moving media are shown to be fundamentally different from stationary magnetoelectrics, despite the formal similarity in the constitutive relations.

  19. Image-driven constitutive modeling of myocardial fibrosis

    Science.gov (United States)

    Wang, Vicky Y.; Niestrawska, Justyna A.; Wilson, Alexander J.; Sands, Gregory B.; Young, Alistair A.; LeGrice, Ian J.; Nash, Martyn P.

    2016-05-01

    Myocardial fibrosis is a pathological process that occurs during heart failure (HF). It involves microstructural remodeling of normal myocardial tissue, and consequent changes in both cardiac geometry and function. The role of myocardial structural remodeling in the progression of HF remains poorly understood. We propose a constitutive modeling framework, informed by high-resolution images of cardiac tissue structure, to model the mechanical response of normal and fibrotic myocardium. This image-driven constitutive modeling approach allows us to better reproduce and understand the relationship between structural and functional remodeling of ventricular myocardium during HF.

  20. Constitutional overhaul of the Assembly of the Republic of Macedonia

    OpenAIRE

    Fatmire Lumani

    2015-01-01

    The paper is a scientific study that aims at analyzing the overhaul of the Assembly of the Republic of Macedonia in the Albanian Constitution. Assembly of the Republic of Macedonia is a representative body of citizens and the bearer of legislative power in the Republic. It is a unicameral body. Its status and its activity is regulated by the Constitution and special laws on Parliament. The Republic of Macedonia is a unitary state, with a multiethnic society. The population is made up, by two ...

  1. Rights of Minors and Constitutional Politics in the German Länder. Legal Framework, Party Strategies, and Constitutional Amendments

    Directory of Open Access Journals (Sweden)

    Lorenz Astrid

    2015-11-01

    Full Text Available The article analyses constitutional politics in the German Länder in the field of minors’ rights. Since this issue seems a purely legal matter dealt with at the federal, European and international level, we should expect similar, almost identically shaped policies at the Länder level. However, the analysis brings considerable variations of constitutional activities in this field to the fore: time, frequency, and contents of respective initiatives vary significantly in the period from 1999 to 2014. These variations were due to different party strategies, diverging party platforms and majority constellations in the Länder. The analysis also shows that the public arguments brought forward in favour of constitutional amendments refer only weakly and randomly to legal provisions and processes at other levels. The political debate supporting extended children's rights rather refers to general observations, to the specific regional context, and constitutional provisions in other Länder. At least with regard to this issue, the multi-level system did not systematically impact on constitutional politics in the Länder. It rather can be understood as an opportunity structure providing parties with multiple realms in which they can pursue their goals. Thus the study shows that federal and regional party strategies are key factors in explaining policy diffusion in multilevel systems.

  2. Emergent situation and rule of administrative law%紧急状态与行政法治

    Institute of Scientific and Technical Information of China (English)

    江必新

    2007-01-01

    Emergent administrative power is a necessary power for dealing with emergent situation. Although different emergent administrative powers under different constitutional systems are different in content, they share the same logic structure. The establishment and the execution of the emergent administrative power shall be subject to the regulation of law. The regulation of emergent administrative power requires for the adoption of various measures with attention to the balance of values.

  3. OEM Emergency Preparedness Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Office of Emergency Management compiles a wide variety of information in support of Emergency Preparedness, including certain elements of the System for Risk...

  4. Dog Bite Emergencies

    Science.gov (United States)

    ... Emergency Care Animal Welfare Veterinary Careers Public Health Dog bite emergencies What do I do if I’ ... vaccination records. What do I do if my dog bites someone? Dog bites are scary for everyone ...

  5. HANARO radiation emergency plan

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Tai

    1997-10-15

    The emergency plan of HANARO (High-flux advanced Neutron Application Reactor) is prepared based on the Korea Atomic Law, the Civil Defence Law, Disaster Protection Law and the emergency related regulation guides such as the NUREG series from USNRC to ensure adequate response capabilities to the emergency event which would cause a significant risk to the KAERI staffs and the public near to the site. Periodic training and exercise for the reactor operators and emergency staffs will reduce accident risks and the release of radioactivities to the environment. The plan describes the organization and staff's duties in the radiation emergency, classification on the radiation accidents, urgent actions of reactor operators in the early state, emergency response activities, maintenance of emergency equipment, training and exercise to improve response capabilities against emergency accidents. (author). 1 tab., 5 figs.

  6. [Emerging noninfectious diseases].

    Science.gov (United States)

    Consiglio, Ezequiel

    2008-11-01

    In recent years, emerging diseases were defined as being infectious, acquiring high incidence, often suddenly, or being a threat or an unexpected phenomenon. This study discusses the hallmarks of emerging diseases, describing the existence of noninfectious emerging diseases, and elaborating on the advantages of defining noninfectious diseases as emerging ones. From the discussion of various mental health disorders, nutritional deficiencies, external injuries and violence outcomes, work injuries and occupational health, and diseases due to environmental factors, the conclusion is drawn that a wide variety of noninfectious diseases can be defined as emergent. Noninfectious emerging diseases need to be identified in order to improve their control and management. A new definition of "emergent disease" is proposed, one that emphasizes the pathways of emergence and conceptual traits, rather than descriptive features.

  7. Emergence of Abductive Reasoning in Mathematical Problem Solving.

    Science.gov (United States)

    Cifarelli, Victor

    This paper examines the novel problem solving actions of a pair of college students. The analysis highlights the role of the solvers' inferential processes including abductions, deductions, and inductions as structuring resources that contribute to both their understanding of the problems they face and the emerging novelty that constitutes their…

  8. Partnerships for Emerging Research Institutions: Report of a Workshop

    Science.gov (United States)

    National Academies Press, 2009

    2009-01-01

    Constituting one-third of all U.S. institutions of higher education, emerging research institutions (ERIs) are crucial to sustaining the nation's technological competitiveness through innovation and workforce development. Many, however, are not fully engaged in sustained sponsored research. This book summarizes the discussions at a workshop…

  9. Emergency Management Offices - Emergency Management Region (polygon)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Data available online through GeoStor at http://www.geostor.arkansas.gov. This file contains location information for Emergency Management Regions in the State of...

  10. [Emergent viral infections

    NARCIS (Netherlands)

    Galama, J.M.D.

    2001-01-01

    The emergence and re-emergence of viral infections is an ongoing process. Large-scale vaccination programmes led to the eradication or control of some viral infections in the last century, but new viruses are always emerging. Increased travel is leading to a rise in the importation of exotic infecti

  11. Emerging technology and ethics

    CERN Document Server

    Wakunuma, Kutoma

    2011-01-01

    This e-book on Emerging Technologies and Ethics includes a collection of essays which explore the future and ethics of emerging information and communication technologies. Articles in the collection include an overview of the legal implications which may be relevant to the ethical aspects of emerging technologies and also ethical issues arising from the mass-take up of mobile technologies.

  12. CONSTITUTIVE RELATION OF UNSATURATED SOIL BY USE OF THE MIXTURE THEORY ( Ⅱ )-LINEAR CONSTITUTIVE EQUATIONS AND FIELD EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    黄义; 张引科

    2003-01-01

    The linear constitutive equations and field equations of unsaturated soils were obtained through linearizing the nonlinear equations given in the first part of this work. The linear equations were expressed in the forms similar to Biot' s equations for saturated porous media. The Darcy's laws of unsaturated soil were proved. It is shown that Biot's equations of saturated porous media are the simplification of the theory. All these illustrate that constructing constitutive relation of unsaturated soil on the base of mixture theory is rational.

  13. Structure and Calibration of Constitutive Equations for Granular Soils

    Directory of Open Access Journals (Sweden)

    Sawicki Andrzej

    2015-02-01

    Full Text Available The form of incremental constitutive equations for granular soils is discussed for the triaxial configuration. The classical elasto-plastic approach and the semi-empirical model are discussed on the basis of constitutive relations determined directly from experimental data. First, the general structure of elasto-plastic constitutive equations is presented. Then, the structure of semiempirical constitutive equations is described, and a method of calibrating the model is presented. This calibration method is based on a single experiment, performed in the triaxial apparatus, which also involves a partial verification of the model, on an atypical stress path. The model is shown to give reasonable predictions. An important feature of the semi-empirical incremental model is the definition of loading and unloading, which is different from that assumed in elasto-plasticity. This definition distinguishes between spherical and deviatoric loading/unloading. The definition of deviatoric loading/unloading has been subject to some criticism. It was therefore discussed and clarified in this paper on the basis of the experiment presented.

  14. Constitutive behaviour of the metastable stainless steel: Sandvik Nanoflex

    NARCIS (Netherlands)

    Post, J.; Datta, K.; Huetink, J.

    2004-01-01

    This article presents a model to describe the constitutive behaviour of corrosion-resistant Sandvik steel NanoflexTM [1] during metal forming and hardening. This material is characterised by different phenomena. The material is metastable, which causes strain-induced transformation to take place dur

  15. Target Soil Impact Verification: Experimental Testing and Kayenta Constitutive Modeling.

    Energy Technology Data Exchange (ETDEWEB)

    Broome, Scott Thomas [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Flint, Gregory Mark [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Dewers, Thomas [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Newell, Pania [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-11-01

    This report details experimental testing and constitutive modeling of sandy soil deformation under quasi - static conditions. This is driven by the need to understand constitutive response of soil to target/component behavior upon impact . An experimental and constitutive modeling program was followed to determine elastic - plastic properties and a compressional failure envelope of dry soil . One hydrostatic, one unconfined compressive stress (UCS), nine axisymmetric compression (ACS) , and one uniaxial strain (US) test were conducted at room temperature . Elastic moduli, assuming isotropy, are determined from unload/reload loops and final unloading for all tests pre - failure and increase monotonically with mean stress. Very little modulus degradation was discernable from elastic results even when exposed to mean stresses above 200 MPa . The failure envelope and initial yield surface were determined from peak stresses and observed onset of plastic yielding from all test results. Soil elasto - plastic behavior is described using the Brannon et al. (2009) Kayenta constitutive model. As a validation exercise, the ACS - parameterized Kayenta model is used to predict response of the soil material under uniaxial strain loading. The resulting parameterized and validated Kayenta model is of high quality and suitable for modeling sandy soil deformation under a range of conditions, including that for impact prediction.

  16. Review of constitutive models and failure criteria for concrete

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jeong Moon; Choun, Young Sun [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    The general behavior, constitutive models, and failure criteria of concrete are reviewed. The current constitutive models for concrete cannot satisfy all of mechanical behavior of concrete. Among several constitutive models, damage models are recommended to describe properly the structural behavior of concrete containment buildings, because failure modes and post-failure behavior are important in containment buildings. A constitutive model which can describe the concrete behavior in tension is required because the containment buildings will reach failure state due to ultimate internal pressure. Therefore, a thorough study on the behavior and models under tension stress state in concrete and reinforced concrete has to be performed. There are two types of failure criteria in containment buildings: structural failure criteria and leakage failure criteria. For reinforced or prestressed concrete containment buildings, concrete cracking does not mean the structural failure of containment building because the reinforcement or post-tensioning system is able to resist tensile stress up to yield stress. Therefore leakage failure criteria will be prior to structural failure criteria, and a strain failure criterion for concrete has to be established. 120 refs., 59 figs., 1 tabs. (Author)

  17. Constitutive Modeling, Nonlinear Behavior, and the Stress-Optic Law

    Science.gov (United States)

    2011-01-01

    extrusion, blow molding , etc. Constitutive models having the form of eqns (5.5) or (5.38) cannot quantitatively describe reversing deformations of...91], as well as in glassy PVC [92]. The change in sign of n implies that the chain segments net orientation is opposite both to their orientation

  18. Generalized constitutive equations for piezo-actuated compliant mechanism

    Science.gov (United States)

    Cao, Junyi; Ling, Mingxiang; Inman, Daniel J.; Lin, Jin

    2016-09-01

    This paper formulates analytical models to describe the static displacement and force interactions between generic serial-parallel compliant mechanisms and their loads by employing the matrix method. In keeping with the familiar piezoelectric constitutive equations, the generalized constitutive equations of compliant mechanism represent the input-output displacement and force relations in the form of a generalized Hooke’s law and as analytical functions of physical parameters. Also significantly, a new model of output displacement for compliant mechanism interacting with piezo-stacks and elastic loads is deduced based on the generalized constitutive equations. Some original findings differing from the well-known constitutive performance of piezo-stacks are also given. The feasibility of the proposed models is confirmed by finite element analysis and by experiments under various elastic loads. The analytical models can be an insightful tool for predicting and optimizing the performance of a wide class of compliant mechanisms that simultaneously consider the influence of loads and piezo-stacks.

  19. How dead is the federal constitutional right to assisted suicide?

    Science.gov (United States)

    Paola, F A

    1998-06-01

    The US Supreme Court recently upheld state laws in New York and Washington that prohibit assisted suicide. In both cases, the judgment of the Court was unanimous. Closer scrutiny of the opinions in the cases, however, suggests that we may not have seen the last of a federal constitutional right to assisted suicide.

  20. The Argument for a Constitutional Right to Communication and Language.

    Science.gov (United States)

    Siegel, Lawrence

    2002-01-01

    This article argues that the need for and right to communication and language is fundamental to the human condition. It contends that given the historic difficulties children who are deaf and hard-of-hearing face, a constitutional right to communication is both necessary and legally sound. Relevant case law is reviewed. (Contains references.) (CR)

  1. The Myth of Modern Politics : An Impossible Constitution

    NARCIS (Netherlands)

    van Rooden, A.

    2010-01-01

    Unlike in pre-modern communities, we consider our democracies to be rationally constituted. Philosopher Aukje van Rooden wonders whether the greatest myth of contemporary politics isn’t our assumption that we can function without a mythological structure. Perhaps that denial is precisely what underl

  2. Constituting Information Technology Research: The Experience of IT Researchers

    Science.gov (United States)

    Pham, Binh; Bruce, Christine; Stoodley, Ian

    2005-01-01

    The collective consciousness of effective groups of researchers is characterized by shared understandings of their research object or territory. In this study, we adopted a phenomenographic approach to investigate information technology (IT) research, and its objects and territories, as they are constituted in the experience of IT researchers.…

  3. Judges as Fiscal Activists: Can Constitutional Review Shape Public Finance?

    Directory of Open Access Journals (Sweden)

    Kantorowicz Jarosław

    2014-07-01

    Full Text Available The judicialization of politics, or alternatively, politization of the judiciary has been much discussed over the last twenty years. Despite this, the way judges influence fiscal policy outcomes remains, to a large extent, unexplored. This paper attempts, at least partially, to fill this research gap. A judicial (constitutional review constitutes the central element of the current analysis since it is considered as a key institutional device through which Constitutional (Supreme Courts intervene in politics, including public finance. Specifically, this paper seeks to investigate empirically whether there is any systematic pattern according to which judges executing judicial review shape fiscal outcomes. The conceptual framework is based on the strategic interaction model and the assumption that the Constitutional Courts reflect public opinion (i.e. the Court as a majoritarian institution. Some preliminary results for a panel of 24 EU countries in the period 1995–2005 suggest that a strong judicial review correlates with a smaller size of government, measured as government income to GDP.

  4. Fundamental Laws of the State: The Spanish Constitution.

    Science.gov (United States)

    Ministerio de Informacion y Turismo, Madrid (Spain).

    This political document is introduced by the head of the Spanish State, His Excellency Don Francisco Franco Bahamonde in a speech given on 22 November 1966 to the session of the Spanish Cores. The speech outlines in general terms the political and philosophical ideals of His Excellency. The Constitution is presented in several sections including:…

  5. Diagnostic criteria for constitutional mismatch repair deficiency syndrome

    DEFF Research Database (Denmark)

    Wimmer, Katharina; Kratz, Christian P; Vasen, Hans F A;

    2014-01-01

    Constitutional mismatch repair deficiency (CMMRD) syndrome is a distinct childhood cancer predisposition syndrome that results from biallelic germline mutations in one of the four MMR genes, MLH1, MSH2, MSH6 or PMS2. The tumour spectrum is very broad, including mainly haematological, brain...

  6. The Teaching of Constitutional Law in American Law Schools.

    Science.gov (United States)

    Haimbaugh, George D., Jr.

    1981-01-01

    A survey of the teaching of constitutional law used questionnaires sent to the dean of every law school approved by the Association of American Law Schools or the American Bar Association. Responses describe the basic course, advanced courses and seminars, teachers, goals, and examinations. (MLW)

  7. Legal Nature and Functions of Referendum in Constitutional Law Theory

    Science.gov (United States)

    Kucherenko, Petr A.; Sangadzhiev, Badma.V.; Velibekov, Murad C.

    2016-01-01

    The relevance of the study of the legal nature and functions of the referendum is conditioned by the increasing dynamics of development of direct democracy in the developed countries and the needs to legalize it in constitutional and legal norms to ensure stability in society. The purpose of this paper is to define the legal nature of the…

  8. The Authoritarian Constitution versus the National Renaissance Front

    Directory of Open Access Journals (Sweden)

    Florin GRECU

    2013-06-01

    Full Text Available On February 27th, 1938 the Constitution laid the ideological and theoretical foundations for the birth of the sole party, called by the new regime The National Renaissance Front (NRF and proclaimed as the only political entity in the state. The NRF was strongly militarized in all its management structures starting with the Directorate to the Superior National Council, because of its corporate-like structure according to constitutional principles and because people were only allowed and granted positions in the party, state or Parliament if they actually had a job. The constitutional order of the monarchy overwrote the stately European or native authoritarian theories by overestimating the state and minimalizing individual rights and freedom. At that time one would not know what regime people who voted for the new regime consecrated by the 27th of February 1938 Constitution had been living in and some of the parliament declarations of the regime’s representatives, when analysed critically, would try to bring light on the article ahead.

  9. Legal and Constitutional Problems of Public Support for Nonpublic Schools.

    Science.gov (United States)

    Whelan, Charles M.; Freund, Paul A.

    Two authors analyze the problems facing aid to nonpublic school education and review relevant court decisions, emphasizing the latest Supreme Court decisions on the subject. Charles M. Whelan provides an analytical framework for determining the constitutionality of various assistance forms. He suggests that each program should be submitted to…

  10. Editorial: The EU and constitutional change: a research proposal

    NARCIS (Netherlands)

    Eijsbouts, W.T.; Beukers, T.W.

    2010-01-01

    The first punctual question arising is how, in its (single) constitutional being, a body such as the Union combines its constituent roots in the original founding authorities (the states) with those, autonomous, in its own institutions. These are the ECJ for interpretation; the political institution

  11. 27 CFR 27.206 - Bottles not constituting approved containers.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bottles not constituting approved containers. 27.206 Section 27.206 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... officer that such bottle is not an approved container for distilled spirits for consumption in the...

  12. The Arab Spring: An Essay on Revolution and Constitutionalism

    DEFF Research Database (Denmark)

    Abat Ninet, Antoni; Tushnet, Mark

    Approaching the concept of Islamic constitutionalism from a comparative perspective, this thought-provoking study by Antoni Abat i Ninet and Mark Tushnet uses traditional Western political theory as a lens to develop a framework for analyzing the events known as the ‘Arab Spring’. Writing...

  13. Constitutional and legal implications of arms control verification technologies

    Energy Technology Data Exchange (ETDEWEB)

    Tanzman, E.A.; Haffenden, R.

    1992-09-01

    United States law can both help and hinder the use of instrumentation as a component of arms control verification in this country. It can foster the general use of sophisticated verification technologies, where such devices are consistent with the value attached to privacy by the Fourth Amendment to the United States Constitution. On the other hand, law can hinder reliance on devices that cross this constitutional line, or where such technology itself threatens health, safety, or environment as such threats are defined in federal statutes. The purpose of this conference paper is to explain some of the lessons that have been learned about the relationship between law and verification technologies in the hope that law can help more than hinder. This paper has three parts. In order to start with a common understanding, part I will briefly describe the hierarchy of treaties, the Constitution, federal statutes, and state and local laws. Part 2 will discuss how the specific constitutional requirement that the government respect the right of privacy in all of its endeavors may affect the use of verification technologies. Part 3 will explain the environmental law constraints on verification technology as exemplified by the system of on-site sampling embodied in the current Rolling Text of the Draft Chemical Weapons Convention.

  14. Foundations of Our Constitution. Reflecting on September 11.

    Science.gov (United States)

    Constitutional Rights Foundation, Los Angeles, CA.

    This lesson plan provides background on six significant historical documents: (1) "Meeting at Runnymede--The Story of King John and the Magna Carta"; (2) "The Mayflower Compact"; (3) "The Declaration of Independence and Natural Rights"; (4) "The Federalist Papers"; (5) "Aristotle: In Search of the Best Constitution"; and (6) "The Pledge of…

  15. Elements of Constitutive Modelling and Numerical Analysis of Frictional Soils

    DEFF Research Database (Denmark)

    Jakobsen, Kim Parsberg

    This thesis deals with elements of elasto-plastic constitutive modelling and numerical analysis of frictional soils. The thesis is based on a number of scientific papers and reports in which central characteristics of soil behaviour and applied numerical techniques are considered. The development...

  16. Constitutive model of rock based on microstructures simulation

    Institute of Scientific and Technical Information of China (English)

    YE Zhou-yuan; HONG Liang; LIU Xi-ling; YIN Tu-bing

    2008-01-01

    The constitutive model of rock can be built by mechanics elements because there are many kinds of damages in rock under varied loads. It is resumed that rock contains many microstructures and a structure of Bingham. The microstructure consists of two embranchments that are the unit of a spring and a gliding slice in series and the unit of a spring and a cementation bar in series, the two units connect each other in parallel. These microstructures are arranged disorderly or in the order of a certain state. A certain distribution of microstructures represents one type of rock. Two kinds of rock's constitutive relationship were deduced by using the model. One is the model in which many parallel microstructures and a structure of Bingham connect in series. And it is used to homogeneous rock. The other is the model in which many microstructures and a structure of Bingham connect in series. And it is used to the rock with much crack or microcrack in a certain direction. The two kinds of constitutive relationship were verified by the studied cases. The constitutive model of rock built by using mechanics elements is verified to be reasonable. Moreover, different types of rocks may be described with mechanics elements with different distributions.

  17. Scaffolding the Inquiry Continuum and the Constitution of Identity

    Science.gov (United States)

    Melville, Wayne; Bartley, Anthony; Fazio, Xavier

    2013-01-01

    This article considers the impact of scaffolding on pre-service science teachers' constitution of identities as teachers of inquiry. This scaffolding has consisted of 2 major components, a unit on current electricity which encompasses the inquiry continuum and an open inquiry which is situated in context of classroom practice. Our analysis…

  18. The influence of genetic constitution on migraine drug responses

    DEFF Research Database (Denmark)

    Christensen, Anne Francke; Esserlind, Ann-Louise; Werge, Thomas

    2016-01-01

    a stronger signal when analyzed together. The associations between response to triptans and genetic load and rs2651899 were partially confirmed in the independent sample. CONCLUSION: We show for the first time an association between genetic constitution and migraine drug response. This is a first step toward...

  19. The political constitution of the EU citizen rights regime

    DEFF Research Database (Denmark)

    Olsen, Tore Vincents

    2011-01-01

    communities and institutions to the good life of citizens, both individually and collectively. Taking the contestation between the different views seriously, the article argues in favour of political constitutionalism, according to which the development of the EU citizen rights regime is the responsibility...

  20. "Contested Rights": The Pedagogy and Logistics of Hosting Constitution Day

    Science.gov (United States)

    Miracle, Amanda; Smith, Michael; Anderson, Kevin; Catlett, Rob

    2016-01-01

    To seriously consider one's rights under the US Constitution, one must grapple with the realization that many rights are not absolute. Instead, they are contested. But how to introduce younger students to such a complex concept, given short attention spans? In this article, we discuss the opportunities, pitfalls, and planning logistics of the 2013…

  1. Multiaxial probabilistic elastic-plastic constitutive simulations of soils

    Science.gov (United States)

    Sadrinezhad, Arezoo

    Fokker-Planck-Kolmogorov (FPK) equation approach has recently been developed to simulate elastic-plastic constitutive behaviors of materials with uncertain material properties. The FPK equation approach transforms the stochastic constitutive rate equation, which is a stochastic, nonlinear, ordinary differential equation (ODE) in the stress-pseudo time space into a second-order accurate, deterministic, linear FPK partial differential equation (PDE) in the probability density of stress-pseudo time space. This approach does not suffer from the drawbacks of the traditional approaches such as the Monte Carlo approach and the perturbation approach for solving nonlinear ODEs with random coefficients. In this study, the existing one dimensional FPK framework for probabilistic constitutive modeling of soils is extended to multi--dimension. However, the multivariate FPK PDEs cannot be solved using the traditional mathematical techniques such as finite difference techniques due to their high computational cost. Therefore, computationally efficient algorithms based on the Fourier spectral approach are developed for solving a class of FPK PDEs that arises in probabilistic elasto-plasticity. This class includes linear FPK PDEs in (stress) space and (pseudo) time - having space-independent but time-dependent, and both space- and time-dependent coefficients - with impulse initial conditions and reflecting boundary conditions. The solution algorithms, rely on first mapping the stress space of the governing PDE between 0 and 2pi using the change of coordinates rule, followed by approximating the solution of the PDE in the 2pi-periodic domain by a finite Fourier series in the stress space and unknown time-dependent solution coefficients. Finally, the time-dependent solution coefficients are obtained from the initial condition. The accuracy and efficiency of the developed algorithms are tested. The developed algorithms are used to simulate uniaxial and multiaxial, monotonic and cyclic

  2. Medical emergencies in Goa

    Directory of Open Access Journals (Sweden)

    Saddichha Sahoo

    2010-01-01

    Full Text Available Background: Most emergencies in Goa arise due to road traffic accidents and drowning, which have been compounded by the rise in number of recorded accidents in 2007 to be above 4000. It is believed that 11 people meet with an accident on Goa′s roads every day and this is expected to rise by 10% by next year. Similar is the case with drownings and other medical emergencies. We therefore aimed to conduct a cross-sectional survey of medical emergencies and identify various types of emergencies presenting to emergency departments. Materials and Methods: Using a stratified random sampling design, all emergencies presenting to the three government hospitals in Goa, which handle 90% of all emergencies currently, were studied on specially designed data sheets in order to collect data. Emergency medical technicians (ETs were placed in the Casualty Ward of the medical colleges and they recorded all emergencies on the data sheet. The collected data were then analyzed for stratification and mapping of emergencies. Results: GMC Hospital attended to majority of emergencies (62%, which were mainly of the nature of accidents or assaults (17% and fever related (17%. Most emergencies were noncritical and about 1% expired. Maximum emergencies also presented from Salcette and Bardez, and occurred among young males in the age group of 19-45 years. Males were also more prone to accidents while females had pregnancies as emergencies. Conclusion: Potential emergency services need to target young males with higher concentrations required in Salcette in South Goa and Bardez in North Goa.

  3. Method of Numerical Modeling for Constitutive Relations of Clay

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In order to study the method of numerical modeling for constitutive relations of clay, on the basis of the principle of interaction between plastic volumetric strain and plastic generalized shear strain, the two constitutive functionals that include the function of stress path were used as the basic framework of the constitutive model, which are able to demonstrate the dependence of stress path.The two partial differential cross terms appear in the expression of stress-strain increment relation, which are used to demonstrate the interaction between plastic volumetric strain and plastic generalized shear strain.The elasoplastic constitutive models of clay under two kinds of stress paths, CTC and TC, have been constructed using the triaxial test results.The three basic characteristics of deformation of soils, pressure sensitivity, dilatancy, and dependence of stress path, are well explained using these two models.Using visualization, the three-dimensional surfaces of shear and volume strains in the whole stress field under stress paths of CTC and TC are given.In addition, the two families of shear and volumetric yield loci under CTC and TC paths are plotted respectively.By comparing the results of deformation under these two stress paths, it has been found that, there are obvious differences in the strain peaks, the shapes of strain surfaces, and the trends of variation of volumetric yield loci, however both families of shear yield loci are similar.These results demonstrate that the influences of stress path on the constitutive relations of clay are considerably large and not negligible.The numerical modeling method that can sufficiently reflect the dependence of stress path is superior to the traditional one.

  4. 77 FR 56835 - Constitution Pipeline Company, LLC; Notice of Intent To Prepare an Environmental Impact Statement...

    Science.gov (United States)

    2012-09-14

    ... Energy Regulatory Commission Constitution Pipeline Company, LLC; Notice of Intent To Prepare an Environmental Impact Statement for the Planned Constitution Pipeline Project, Request for Comments on... environmental impacts of the proposed Constitution Pipeline Project (Project) involving construction...

  5. Taking Causality Seriously in Comparative Constitutional Law: Insights from Comparative Politics and Comparative Political Economy

    OpenAIRE

    Whytock, CA

    2015-01-01

    By highlighting the many ways that constitutions vary, comparative constitutional law raises interesting and important causal questions: What explains cross-national constitutional variation, and what are the real-world consequences of different constitutional arrangements? But comparative constitutional law scholarship so far has done relatively little to address these issues of constitutional causes and consequences in a rigorous manner. In this paper, I argue that scholars have much to gai...

  6. The Research on ZHAO Huai-yu about Ancestors of Poetry%家声我敢负高曾--赵怀玉述祖诗文研究

    Institute of Scientific and Technical Information of China (English)

    蓝士英; 王文荣

    2016-01-01

    ZHAO Huai-yu was a famous scholar in Qing Dynasty. He was considered as one of the seven Piling poets and focused on the poetry of classical Chinese words. Five Handwriting Sequence is a long article about the morality of his ancestors. According to the lines, we can feel the kind heart of transferring the ancestors’good deeds and characters. In addition, he also has a certain number of poetry about his progenitors. Through those po-etry, we could find the power of his glory and pride, the defence and uplift. At the same time, there are lingering stress and anxiety. His poetry of progenitors offers a variety of view. According to the literary point of view, it is necessary to concentrate on the origin and evolution. From the angle of history, the relationship between family history and the official history was fascinating. Last but not least, from the angle of sociology, readers can think deeply about the relationship between the individual and the whole family.%赵怀玉,清代著名文人,“毗陵七子”之一,工诗古文词。《五世手迹跋》是其缕述祖德的一篇长文,字里行间,跃动着欲传先祖懿德嘉行之拳拳之心。赵怀玉另有一定数量的述祖诗文,于中可见其对待先祖的荣光与骄傲、守护与振拔的动力,还有挥之不去的压力与焦虑。其述祖诗文,提供了多种考察角度,从文学的角度看,其渊源流变值得关注;从历史的角度,家族私史与官史的关系颇堪玩味;从社会学的角度,可思考个体与家族的关系。

  7. (PostColonial State and Constitutionalism in India. Differences and Crossings

    Directory of Open Access Journals (Sweden)

    Giorgio Grappi

    2013-07-01

    Full Text Available The article argues that the end of the formal division of the world between a colonizing metropolis and a colonized periphery requires a different reading of the State’s history. The essay deals with the relation between the formation of British India and the development of Indian nationalist movement through the events related to the ‘tiger of Mysore’, Tipu Sultan, and the swadeshi movement as portrayed in Tagore’s The Home and the World. The essay shows how colonial constitutionalism developed through the contemporary affirmation of the rule of law and the colonial difference. The postcolonial State emerged via concrete crossing of this difference, which today allows a different reading of the political discourses beyond the affirmation of the State as the barycenter of political organization at a global scale.

  8. 15 years of constitutional review in the Supreme Court of Estonia : systematized extracts of constitutional review judgments and rulings of the Supreme Court en banc and the Constitutional Review Chamber in 1993-2008 / Riigikohus ; toim. ja eess.: Ge

    Index Scriptorium Estoniae

    2009-01-01

    Sisaldab ka: The outset of judicial constitutional review / Rait Maruste. Judicial constitutional review at the turn of the century / Uno Lõhmus. Judicial constitutional review through the eyes of Chancellor of Justice / Eerik-Juhan Truuväli. The courts and the Supreme Court in concrete norm control / Madis Ernits

  9. Measures of the constitutive immune system are linked to diet and roosting habits of neotropical bats.

    Directory of Open Access Journals (Sweden)

    Karin Schneeberger

    Full Text Available Ecological and social factors are central in the emergence and transmission of infectious diseases, thus bearing the potential for shaping a species' immune functions. Although previous studies demonstrated a link between social factors and the cellular immune system for captive mammals, it is yet poorly understood how ecological factors are connected with the different branches of the immune system in wild populations. Here, we tested how variation in aspects of the constitutive cellular and humoral immune system of free ranging bats is associated with two ecological factors that likely influence the putative risk of species to become infected by parasites and pathogens: diet and shelter. We found that white blood cell counts of 24 syntopic Neotropical bat species varied with the species' diet and body mass. Bats that included at least partially vertebrates in their diet exhibited the highest white blood cell counts, followed by phytophagous and insectivorous species, which is in agreement with the assumption that the immune system varies with the pathogen transmission risk of a trophic level. The soluble part of the constitutive immune response, assessed by an in vitro bacterial killing assay, decreased with increasing roost permanence. Our results suggest that the ecology is an important factor in the evolution of the immune system in bats and probably also other mammals.

  10. Data journeys: Capturing the socio-material constitution of data objects and flows

    Directory of Open Access Journals (Sweden)

    Jo Bates

    2016-07-01

    Full Text Available In this paper, we discuss the development and piloting of a new methodology for illuminating the socio-material constitution of data objects and flows as data move between different sites of practice. The data journeys approach contributes to the development of critical, qualitative methodologies that can address the geographic and temporal scale of emerging knowledge infrastructures, and capture the ‘life of data’ from their initial generation through to re-use in different contexts. We discuss the theoretical development of the data journeys methodology and the application of the approach on a project examining meteorological data on their journey from initial production through to being re-used in climate science and financial markets. We then discuss three key conceptual findings from this project about: (1 the socio-material constitution of digital data objects, (2 ‘friction’ in the movement of data through space and time and (3 the mutability of digital data as a material property that contributes to driving the movement of data between different sites of practice.

  11. When ethical reform became law: the constitutional concerns raised by recent legislation in Taiwan.

    Science.gov (United States)

    Su, Yi-Chen

    2014-07-01

    In an effort at ethical reform, Taiwan recently revised the Hospice Palliative Care Law authorising family members or physicians to make surrogate decisions to discontinue life-sustaining treatment if an incompetent terminally ill patient did not express their wishes while still competent. In particular, Article 7 of the new law authorises the palliative care team, namely the physicians, to act as sole decision-makers on behalf of the incompetent terminally ill patient's best interests if no family member is available. However, the law fails to provide guidance as to what constitutes the patient's best interests or what specific procedures the treating physicians should follow, and so has raised constitutional concerns. It may be difficult to translate ethical reform into law but it is not impossible if essential requirements are carefully followed. First, there must be substantial nexus between the purpose of the statute and the measures provided under the statute. Second, advocates need to convince the public that futility or waste has amounted to a public health emergency so as to justify lower procedural requirements. Third, a remedy or compensation should be available if the surrogate decisions have not been appropriately made. Fourth,minimum procedural safeguards are necessary even though the statute is intended to reduce the procedural burdens of making surrogate decisions on behalf of incompetent patients who lack family members and did not express their wishes while still competent.

  12. Right to Freedom of Speech and Expression (constitutional legal framework and Constitutional Court practice in the Republic of Croatia

    Directory of Open Access Journals (Sweden)

    Mato Arlović

    2016-05-01

    Full Text Available This paper analyses the connection and inter relationship of freedom as the highest value of constitutional order of the Republic of Croatia and the highest ideal of contemporary democracy and constitutional state with the right to freedom of speech and expression. By analysing that interrelationship, the intention to confirm the thesis that the right to freedom of speech and expression is just one (albeit very importanthuman right and fundamental freedom arises. It has been extracted from freedoms as the highest value and as one which is always returned to in such a way that affects the scope and content of it being achieved in relation to the imagined ideal of freedom and the given reality. The right to freedom of speech and expression is analysed as just one of the fundamental supports for building a democratic society of rule of law and Constitution. In this context, the function of the indispensable condition for achieving other human rights and fundamental freedoms is also analysed. Furthermore, it is considered as a right within which, through its content, includes a range of other rights and freedoms. It should be considered from a theoretical viewpoint as a so called legal construction. This paper analyses the constitutional legal framework in the Republic of Croatia related to the right to freedom of speech and expression. In that analysis, particular attention is given to the subject, content and characteristics of the right to freedom of speech and expression and the practice of European Court of Human Rights and the Constitutional Court of the Republic of Croatia which protect this right.

  13. An Estimation Method of a Constitutive-law for the Rod Model of DNA using Discrete-Structure Simulations

    CERN Document Server

    Hinkle, Adam R; Palanthandalam-Madapusi, Harish J

    2009-01-01

    The continuum-rod model has emerged as an efficient tool to describe the long-length-scale structural-deformations of DNA which are critical to understanding the nature of many biological processes such as gene expression. However, a significant challenge in continuum-mechanics-based modeling of DNA is to estimate its constitutive law, which follows from its interatomic bond-stiffness. Experiments and all-atom molecular dynamics (MD) simulations have suggested that the constitutive law is nonlinear and non-homogeneous (sequence-dependent) along the length of DNA. In this paper, we present an estimation method and a validation study using discrete-structure simulations. We consider a simple cantilever-rod with an artificially constructed, discrete lattice-structure which gives rise to a constitutive law. Large deformations are then simulated. An effective constitutive-law is estimated from these deformations using inverse methods. Finally, we test the estimated law by employing it in the continuum rod-model an...

  14. Emergency in Burn; Burn in Emergency

    Directory of Open Access Journals (Sweden)

    Yalcin Bayram

    2012-06-01

    Full Text Available Physicians who first meet with burned patients are often emergency service employees. When the patient was admitted to emergency service, especially in patients with major burn injury, is a matter should be dealt with strongly. Before sending the patients to a burn center, some interventions could became life saving which should be done as a first line treatment. Herein, review of the literature related to emergency burn treatment was performed and presented to all physicians as a summary guide. In addition, some questions such as how should be physician, who first meet with the burned patient, evaluated the patient, what should be physician paid attention, which principles should be employed for fluid replacement, how should be approached to burn wound are tried to be addressed. [TAF Prev Med Bull 2012; 11(3.000: 365-368

  15. SUPERVASMOL POISONING: AN EMERGING ENT EMERGENCY

    Directory of Open Access Journals (Sweden)

    Mitta

    2016-05-01

    Full Text Available Poisoning is one of the commonest modes of suicide in India. Supervasmol poisoning is one of the commonest modes of suicidal attempt in our region. The common cause for consumption of hair dye is by suicidal intent or accidental oral ingestion. There is no specific antidote for Supervasmol poisoning. Management is only symptomatic and supportive with emergency tracheostomy in majority of cases. Hence, we conducted this study to emphasize the role of ENT surgeon in Supervasmol poisoning. STUDY DESIGN Prospective study. MATERIALS AND METHODS We present a total of 79 cases of Supervasmol poisoning who attended the Emergency Department of Narayana Medical College and General Hospital, Nellore. RESULTS All patients were between age group 15-35 yrs. Females are more than males. More patients were in second decade; 55 cases presented in acute phase, 51 patients underwent tracheostomy and four patients were brought dead. CONCLUSION Emergency tracheostomy is a life saving measure in severe stridor

  16. Emergências hipertensivas Hypertensive emergencies

    OpenAIRE

    Gilson Soares Feitosa-Filho; Renato Delascio Lopes; Nilson Tavares Poppi; Hélio Penna Guimarães

    2008-01-01

    As urgências e as emergências hipertensivas são ocorrências clínicas que podem representar mais de 25% dos atendimentos a urgências médicas. O médico deverá estar habilitado a diferenciá-las, pois o prognóstico e o tratamento são distintos. Estima-se que 3% de todas as visitas às salas de emergência decorrem de elevações significativas da pressão arterial. Nos quadros relacionados a estes atendimentos, a emergência hipertensiva é a entidade clínica mais grave que merece cuidados intensivos. É...

  17. 76 FR 13283 - Continuation of the National Emergency With Respect to Iran

    Science.gov (United States)

    2011-03-10

    ... Documents#0;#0; ] Notice of March 8, 2011 Continuation of the National Emergency With Respect to Iran On... Iran pursuant to the International Emergency Economic Powers Act (50 U.S.C. 1701-1706) to deal with the... States constituted by the actions and policies of the Government of Iran. On May 6, 1995, the...

  18. Constitutive equation for polymer networks with phonon fluctuations.

    Science.gov (United States)

    Hansen, Rasmus; Skov, Anne Ladegaard; Hassager, Ole

    2008-01-01

    Recent research by Xing [Phys. Rev. Lett. 98, 075502 (2007)] has provided an expression for the Helmholtz free energy related to phonon fluctuations in polymer networks. We extend this result by constructing the corresponding nonlinear constitutive equation, usable for entirely general, volume conserving deformation fields. Constitutive equations for the sliplink model and the tube model are derived and the three models are examined by comparison with each other and with data from Xu and Mark [Rubber Chem. Technol. 63, 276 (1990)] and Wang and Mark [J. Polym. Sci., Part B: Polym. Phys. 30, 801 (1992)]. Elastic moduli are derived for the three models and compared with the moduli determined from the chemical stoichiometry. We conclude that the sliplink model and the phonon fluctuation model are relatively consistent with each other and with the data. The tube model seems consistent neither with the other models nor with the data.

  19. Strategic approach to the globalization of sasang constitutional medicine.

    Science.gov (United States)

    Lee, Myeong Soo

    2011-01-01

    The workshop on "Strategic Approach to the Globalization of Sasang Constitutional Medicine (SCM)" was held in the Korea Institute of Oriental Medicine (KIOM) on September 18, 2009. This workshop was designed to discuss and brainstorm the strategic approach to the globalization of SCM, one of the unique systems in Korean Traditional Medicine, with three topics and an extensive panel discussion. Professor Edwin Cooper, Editor-in-Chief of eCAM, gave a commemorative lecture for publication of the second supplement of eCAM entitled "Sasang Constitutional Medicine as a Holistic Tailored Medicine". The other two presenters suggested some practical methods for globalization of SCM on the basis of their experiences. After the three main presentations, there was a panel discussion session for further development of workshop topics, extended by five other external experts. They discussed the benefits, limitations and essentials for globalization of Korean Traditional Medicine, specifically SCM, from bench to bedside.

  20. Clarifying Limbo: Disentangling Indigenous Autonomy from the Mexican Constitutional Order

    Directory of Open Access Journals (Sweden)

    Sprague Ian Flannigan

    2016-05-01

    Full Text Available In contrast to U.S. Federal Indian law, which has classified indigenous tribes as “domestic dependent nations” since the early 19th century, Mexican law has only recently begun to define the political and territorial autonomy of indigenous groups. This paper contrasts the Mexican approach to this problem to that of the United States, first describing Mexico’s 2001’s constitutional reforms and their failure to clarify the nature of tribal sovereignty. It then analyzes recent court cases that protect tribal political and territorial autonomy by applying rights to consultation contained in the International Labor Organization’s Indigenous and Tribal People’s Convention 169 (“ILO 169” and the Mexican Constitution. It concludes by arguing that in spite of this effort by the courts, Mexican law still requires a comprehensive legislative or diplomatic resolution of the lack of clarity surrounding the political and territorial autonomy of its indigenous groups.

  1. Dynamic constitutive model for soils considering asymmetry of skeleton curve

    Institute of Scientific and Technical Information of China (English)

    Guoxing Chen; Hua Pan; Hui Long; Xiaojun Li

    2013-01-01

    Based on the asymmetric characteristic of skeleton curve obtained from dynamic tests on soils, a func-tion with double asymptotes is proposed for describing the dynamic constitutive relations of soils. The hysteresis loops observed during unloading and reloading show the same form as the skeleton curve and are constructed by taking the ultimate stress as the corresponding asymptote. The coefficient of initial unloading modulus is used to ensure that the constructed hysteresis loop fits well with the experimental data. Then, a new dynamic constitutive model considering the asymmetry of skeleton curve is elaborated. The verification tests on saturated Nanjing fine sand are performed using a hollow cylinder apparatus to verify the applicability of the UD model. It is found that the predicted curves by the UD model agree well with the test data.

  2. Overall Dynamic Constitutive Relations of Micro-structured Elastic Composites

    CERN Document Server

    Nemat-Nasser, Sia

    2011-01-01

    A method for homogenization of a heterogeneous (finite or periodic) elastic composite is presented. It allows direct, consistent, and accurate evaluation of the averaged overall frequency-dependent dynamic material constitutive relations. It is shown that when the spatial variation of the field variables is restricted by a Bloch-form (Floquet-form) periodicity, then these relations together with the overall conservation and kinematical equations accurately yield the displacement or stress modeshapes and, necessarily, the dispersion relations. It also gives as a matter of course point-wise solution of the elasto-dynamic field equations, to any desired degree of accuracy. The resulting overall dynamic constitutive relations however, are general and need not be restricted by the Bloch-form periodicity. The formulation is based on micro-mechanical modeling of a representative unit cell of the composite proposed by Nemat-Nasser and coworkers; see, e.g., [1] and [2].

  3. RECONSIDERING FRIEDMAN, RICHARDSON AND THE CONSTITUTIVE A PRIORI

    Directory of Open Access Journals (Sweden)

    Álvaro J. Peláez Cedrés

    2006-08-01

    Full Text Available The contemporary interpretations on the a priori in the philosophy of science have been dominated mainly by a semantic and a pragmatic reading. Although the contribution of these conceptions has been valuable, it is my point of view that they have rejected without justification the fundamental meaning of the original Kantian notion, that is, the idea of the constitution of the experience. In this paper I intend to do two things: first, after a presentation of the argument between Friedman and Richardson, both supporters of the semantic and pragmatic readings, I will show the historical reasons that one can use to reject the semantic interpretation of the a priori. Then, I will sketch a conception of the constitutive a priori which, tracking the proposals of philosophers of the 19th century, will insist on the idea that the experience is dominated by a formal function which consists in the production of “invariants”.

  4. Constitutive Mixed Mode Behavior of Cracks in Concrete

    DEFF Research Database (Denmark)

    Jacobsen, Jonas Sejersbøl

    and a better basis for the assessment of the service life of the structure. The constitutive relation between Mode I crack opening and the normal stresses across the crack is well described through the Fictitious Crack Model (FCM) and related models. However, after a crack in concrete is initiated, the crack...... may open in mixed mode, i.e. a combination of opening and sliding. To get a thorough description of the structural consequences it is important to include the stress transferring effects related to the mixed mode opening. The existing constitutive mixed mode models either have a rather extensive model...... formulation or are based on one or more model parameters which are difficult to conceive and give a mechanical interpretation. To some extent this may be explained by the sparse experimental basis for the mixed mode cracking in concrete. In this thesis a series of new mixed mode experiments are presented...

  5. Comparison of Sasang Constitutional Medicine, Traditional Chinese Medicine and Ayurveda

    Directory of Open Access Journals (Sweden)

    Jong Yeol Kim

    2011-01-01

    Full Text Available Sasang constitutional medicine (SCM, traditional Chinese medicine (TCM and Ayurveda are three different forms of Asian traditional medicine. Although these traditions share a lot in common as holistic medicines, the different philosophical foundations found in each confer distinguishing attributes and unique qualities. SCM is based on a constitution-based approach, and is in this way relatively more similar to the Ayurvedic tradition than to the TCM, although many of the basic SCM theories were originally derived from TCM, a syndrome-based medicine. SCM and TCM use the same botanical materials that are distributed mainly in the East Asian region, but the basic principles of usage and the underlying rationale are completely different from each other. Meanwhile, the principles of the Ayurvedic use of botanical resources are very similar to those seen in SCM, but the medicinal herbs used in Ayurveda generally originate from the West Asian region which displays a different spectrum of flora.

  6. Phenomenology and Sociological Research: The Constitution of “Friendship”

    Directory of Open Access Journals (Sweden)

    Jochen Dreher

    2016-01-01

    Full Text Available This analysis combines phenomenological and sociological research for an investigation of the social relationship of “friendship”. From a phenomenological perspective, it focuses on the epistemological basis, on the subjective constitution of the phenomenon of “friendship”. The social construction of friendship however, is described from a sociological research perspective with reference to concrete empirical expressions of this specific social relationship. The key for the reflections on friendship is the adaptation of Edmund Husserl’s method of phenomenological reduction for the analysis of social phenomena, based on the argumentations of Alfred Schutz and Aron Gurwitsch. This leads to the assumption that friendship is symbolically constituted with reference to everyday transcendent ideas which substantially define the specific expression of this social relationship.

  7. Concentration of constitutional and thermal defects in UAl4

    Science.gov (United States)

    Gargano, P. H.; Kniznik, L.; Alonso, P. R.; Forti, M. D.; Rubiolo, G. H.

    2016-09-01

    The point defect structure of intermetallic compound oI20 UAl4 is investigated using a combination of the statistical mechanical Wagner-Schottky model and first-principles calculations within a projector augmented wave pseudopotential method in conjunction with the generalized gradient approximation. The formation energies of eight point defects were calculated taking into account the four sublattices. The point defect concentrations are calculated as function of temperature and deviation from stoichiometry. Our results show that the aluminum antisite is the constitutional point defect on the Al-rich side. At this off-stoichiometric side the dominant thermal defect is an interbranch defect where four constitutional antisite aluminum atoms are replaced by five uranium vacancies. The point defect effective formation energies are obtained and these results allow us to identify the antistructure bridge mechanism as the most probable for the diffusion for Al atoms in the Al-rich UAl4 intermetallic compound.

  8. Constitutive equations for meeting elevated-temperature-design needs

    Energy Technology Data Exchange (ETDEWEB)

    Pugh, C.E.; Robinson, D.N.

    1981-01-01

    Constitutive equations for representing the inelastic behavior of structural alloys at temperatures in the creep regime are discussed from the viewpoint of advances made over the past decade. An emphasis is placed on the progress that has been made in meeting the needs of the program whose design process is based in part on a design-by-inelastic-analysis approach. In particular, the constitutive equations that have been put into place for current use in design analyses are discussed along with some material behavior background information. Equations representing short-term plastic and long-term creep behaviors are considered. Trends towards establishing improved equations for use in the future are also described. Progress relating to fundamentals of continuum mechanics, physical modeling, phenomenological modeling, and implementation is addressed.

  9. A thermomechanical crystal plasticity constitutive model for ultrasonic consolidation

    KAUST Repository

    Siddiq, Amir

    2012-01-01

    We present a micromechanics-based thermomechanical constitutive model to simulate the ultrasonic consolidation process. Model parameters are calibrated using an inverse modeling approach. A comparison of the simulated response and experimental results for uniaxial tests validate and verify the appropriateness of the proposed model. Moreover, simulation results of polycrystalline aluminum using the identified crystal plasticity based material parameters are compared qualitatively with the electron back scattering diffraction (EBSD) results reported in the literature. The validated constitutive model is then used to simulate the ultrasonic consolidation process at sub-micron scale where an effort is exerted to quantify the underlying micromechanisms involved during the ultrasonic consolidation process. © 2011 Elsevier B.V. All rights reserved.

  10. A constitutive model for sintering of granulated ceramic powders

    Science.gov (United States)

    Shinagawa, K.; Hirashima, Y.

    1998-05-01

    Sintering behavior of granulated powder is investigated to develop a constitutive model for deformation analysis of ceramic powder compacts during sintering. Spray-dried alumina is compacted by CIPing (cold isostatic pressing) and sintered at various temperatures. Shrinkage and the change in grain size of the compacts during sintering are revealed in relation to the inhomogeneous microstructure consisting of fractured and unfractured granules as a consequence of the compaction. A constitutive model for the ceramic powder compacts having the internal structure is presented; The difference in grain growth in dense and sparse regions of the compacts is taken into consideration to the model. The results calculated by the model show good agreement with that obtained by experiment.

  11. Derivation of stiffness matrix in constitutive modeling of magnetorheological elastomer

    Science.gov (United States)

    Leng, D.; Sun, L.; Sun, J.; Lin, Y.

    2013-02-01

    Magnetorheological elastomers (MREs) are a class of smart materials whose mechanical properties change instantly by the application of a magnetic field. Based on the specially orthotropic, transversely isotropic stress-strain relationships and effective permeability model, the stiffness matrix of constitutive equations for deformable chain-like MRE is considered. To valid the components of shear modulus in this stiffness matrix, the magnetic-structural simulations with finite element method (FEM) are presented. An acceptable agreement is illustrated between analytical equations and numerical simulations. For the specified magnetic field, sphere particle radius, distance between adjacent particles in chains and volume fractions of ferrous particles, this constitutive equation is effective to engineering application to estimate the elastic behaviour of chain-like MRE in an external magnetic field.

  12. Canada's constitutional separation of (wind) power

    Energy Technology Data Exchange (ETDEWEB)

    Valentine, Scott Victor [Lee Kuan Yew School of Public Policy, National University of Singapore (Singapore)

    2010-04-15

    This paper investigates the impact that a federal government structure has on strategic selection of renewable energy policy instruments. The context for this study centers on wind power development in Canada. Canada is a nation that is blessed by all the attributes necessary to catalyze global leadership in installed wind power capacity. Unfortunately, the constitutional separation of powers that underpins Canada's federal system impedes the creation of a national wind power development strategy because Canada's provinces have constitutional authority over electricity governance. The insights gleaned from the case study are used to develop a conceptual framework for understanding the impact that federal structure has on policy instrument selection and efficacy under areas of federal, regional and concurrent policy jurisdiction. Finally, this framework is re-applied to identify specific approaches the Canadian federal government could take to resolve what currently amounts to be a fragmented, ineffective approach to wind power development planning. (author)

  13. Constitutionality of the Plachimada Tribunal Bill, 2011: An Assessment - Comment

    Directory of Open Access Journals (Sweden)

    Sujith Koonan

    2011-09-01

    Full Text Available The Plachimada Coca-Cola Victims Relief and Compensation Claims Special Tribunal Bill, 2011 was passed by the Kerala Legislative Assembly on 24 February 2011. The Bill provides for the establishment of a special tribunal to settle disputes between the local residents and the Hindustan Coca Cola Company in Plachimada for recovery of compensation for damages caused to individuals, property and the environment by the company. The Bill is reserved for the assent of the President of India. In the meantime, the central government has sought clarifications on the Kerala government’s competence under the Constitution to adopt the Bill. The major issue is the perceived inconsistency between the Bill and some of the central environmental laws. Thus, the constitutional validity of the Bill is in doubt. In this background, this paper examines the issue of legislative competence of the Kerala government to adopt the Bill.

  14. BILF1 Mediated Transformation Correlates with Constitutive Signaling

    DEFF Research Database (Denmark)

    Lyngaa, Rikke Birgitte

    2009-01-01

    the investigation of BILF1's oncogenic potential a clear correlation between G_alpha_i signaling and (a) focus formation, (b) NFAT activity, (c) VEGF secretion and (d) tumor onset an foramtion was revealed. Interestingly also a silenced receptor, EAT-BILF1 induced tumors in vivo although to a lesser extent than...... the fully active receptor. This suggests the existence of an alternative signaling pathway activated by BILF1. The rhesus EBV BILF1 also signals constitutive via G_alpha_i and induced foci formation of 3T3 cells but it was not able to induce tumor in mice or induce secretion of VEGF to the same extent...... as BILF1. In this thesis BILF1 is revealed as a potential oncogene, inducing transformation of NIH 3T3 cells and tumors in vivo, and this ability is clearly correlated to the constitutive activity through G_alpha_I....

  15. Purification and Properties of the Constitutive Arginase of Evernia prunastri.

    Science.gov (United States)

    Martín-Falquina, A; Legaz, M E

    1984-12-01

    Constitutive arginase (molecular weight 330,000) 920-fold purified from Evernia prunastri thallus, is activated by putrescine, l-ornithine, and agmatine with K(a) values of 2.7, 1.1, and 5.8 millimolar, respectively. Constitutive arginase is also activated by endogenous l-arginine, reaching its maximum activity at 16 hours of incubation on Tris-HCl (pH 9.15) with a subsequent decrease. Urea behaves as a mixed inhibitor of the enzyme with a K(i) value of 2.6 millimolar. Atranorin and evernic acid behave as in vitro activators of the enzyme; usnic acid does not have any significant effect as activator.

  16. Viscoelastoplastic constitutive model for creep deformation behavior of asphalt sand

    Institute of Scientific and Technical Information of China (English)

    叶永; 杨新华; 陈传尧

    2008-01-01

    A uniaxial viscoelastoplastic model that can describe whole creep behaviors of asphalt sand at different temperatures was presented.The model was composed of three submodels in series,which describe elastoplastic,viscoelastic and viscoplastic characteristics respectively.The constitutive equation was established for uniaxial loading condition,and the creep representation was also obtained.The constitutive parameters were determined by uniaxial compression tests under controlled-stress of 0.1 MPa with five different test temperatures of 20,40,45,50 and 60 ℃.Expressions of the model parameters in terms of temperatures were also given.The model gave prediction at various temperatures consistent with the experimental results,and can reflect the total deformation characterization of asphalt sands.

  17. CONSTITUTIVE RELATION OF DISCONTINUOUS REINFORCED METAL-MATRIX COMPOSITES

    Institute of Scientific and Technical Information of China (English)

    季葆华; 王自强

    2001-01-01

    A micromechanical model is developed to simulate the mechanical behaviors of discontinuous reinforced composites. The analysis for a representative unit cell is based on the assumption of a periodic array of aligned reinforcements.The minimum energy principle is used to determine the unknown coefficients of the displacement field of the unit cell. The constitutive behavior of composites is studied to obtain the relationship between the main variables of matrix and reinforcements.It is concluded that the flow strength of composites is strongly influenced by volume fraction, aspect ratio of reinforcement, and the strain hardening exponent of matrix.An analytical constitutive relation of composites is obtained. The predicted results are in agreement with the existing experimental and numerical results.

  18. Constitutional and legal base for sustainable development in Macedonia

    OpenAIRE

    Matlievska, Margarita

    2012-01-01

    ABSTRACT Sustainable development, as a new paradigm of development, impose a challenge for every country which recognize it as precognition for better life and wellbeing of its citizen’s. Each country has a different, national solution for realization and implementation of this new philosophy of development. Yet, the essential elements that enable the creation of sustainable development policies are the Constitution of the state and its legislative, both containing the basic principles of ...

  19. Characters of DNA Constitution in the Rye B Chromosome

    Institute of Scientific and Technical Information of China (English)

    Hong Long; Zhong-Xia Qi; Xiao-Ming Sun; Cheng-Bin Chen; Xiu-Lan Li; Wen-Qin Song; Rui-Yang Chen

    2008-01-01

    We have used chromosome microdissection and microcloning to construct a DNA library of the entire B chromosome (B) of rye. New rye B-specific sequences have been screened from this pool, blasted with other sequences and analyzed to elucidate the characters of DNA constitution and the possible pathway of the origin of the rye B chromosome. We report the discovery of a new sequence that is specific to the rye B centromere.

  20. Helix 11 Dynamics is Critical for Constitutive Androstane Receptor Activity

    OpenAIRE

    Wright, Edward; Busby, Scott A.; Wisecarver, Sarah; Vincent, Jeremy; Griffin, Patrick R.; Fernandez, Elias J.

    2011-01-01

    The constitutive androstane receptor (CAR) transactivation can occur in the absence of exogenous ligand and this activity is enhanced by agonists TCPOBOP and meclizine. We use biophysical and cell-based assays to show that increased activity of CAR(TCPOBOP) relative to CAR(meclizine) corresponds to a higher affinity of CAR(TCPOBOP) for the steroid receptor coactivator-1. Additionally, steady-state fluorescence spectra suggest conformational differences between CAR(TCPOBOP):RXR and CAR(meclizi...