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Sample records for analytical laboratory rtal

  1. Road Transportable Analytical Laboratory (RTAL) system

    Energy Technology Data Exchange (ETDEWEB)

    Finger, S.M. [Engineering Computer Optecnomics, Inc., Annapolis, MD (United States)

    1995-10-01

    The goal of the Road Transportable Analytical Laboratory (RTAL) Project is the development and demonstration of a system to meet the unique needs of the DOE for rapid, accurate analysis of a wide variety of hazardous and radioactive contaminants in soil, groundwater, and surface waters. This laboratory system has been designed to provide the field and laboratory analytical equipment necessary to detect and quantify radionuclides, organics, heavy metals and other inorganic compounds. The laboratory system consists of a set of individual laboratory modules deployable independently or as an interconnected group to meet each DOE site`s specific needs.

  2. Innovative technology summary report: Road Transportable Analytical Laboratory (RTAL)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    The Road Transportable Analytical Laboratory (RTAL) has been used in support of US Department of Energy (DOE) site and waste characterization and remediation planning at Fernald Environmental Management Project (FEMP) and is being considered for implementation at other DOE sites, including the Paducah Gaseous Diffusion Plant. The RTAL laboratory system consists of a set of individual laboratory modules deployable independently or as an interconnected group to meet each DOE site`s specific analysis needs. The prototype RTAL, deployed at FEMP Operable Unit 1 Waste Pits, has been designed to be synergistic with existing analytical laboratory capabilities, thereby reducing the occurrence of unplanned rush samples that are disruptive to efficient laboratory operations.

  3. Road Transportable Analytical Laboratory (RTAL) system: Volume III, Appendices C through J. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Finger, S.M.; De Avila, J.C.; Keith, V.F.

    1996-08-01

    The Road Transportable Analytical Laboratory (RTAL) provides a portabler laboratory for the analysis of soils, ground water, and surface water. This report presents data from a soils sample TCLP VOA and SVOA report, aqueous sample RCRA metals report, soils sample total and isotopic uranium report, SVOA sample analytical performance report, and and RCRA metal sample analytical performance report.

  4. Road Transportable Analytical Laboratory system. Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Finger, S.M.; Keith, V.F.; Spertzel, R.O.; De Avila, J.C.; O`Donnell, M.; Vann, R.L.

    1993-09-01

    This developmental effort clearly shows that a Road Transportable Analytical Laboratory System is a worthwhile and achievable goal. The RTAL is designed to fully analyze (radioanalytes, and organic and inorganic chemical analytes) 20 samples per day at the highest levels of quality assurance and quality control. It dramatically reduces the turnaround time for environmental sample analysis from 45 days (at a central commercial laboratory) to 1 day. At the same time each RTAL system will save the DOE over $12 million per year in sample analysis costs compared to the costs at a central commercial laboratory. If RTAL systems were used at the eight largest DOE facilities (at Hanford, Savannah River, Fernald, Oak Ridge, Idaho, Rocky Flats, Los Alamos, and the Nevada Test Site), the annual savings would be $96,589,000. The DOE`s internal study of sample analysis needs projects 130,000 environmental samples requiring analysis in FY 1994, clearly supporting the need for the RTAL system. The cost and time savings achievable with the RTAL system will accelerate and improve the efficiency of cleanup and remediation operations throughout the DOE complex.

  5. Analytical Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Analytical Labspecializes in Oil and Hydraulic Fluid Analysis, Identification of Unknown Materials, Engineering Investigations, Qualification Testing (to support...

  6. Analytical Laboratories

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s analytical laboratories in Pittsburgh, PA, and Albany, OR, give researchers access to the equipment they need to thoroughly study the properties of materials...

  7. Radioactive Materials Analytical Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Laing, W.R.; Corbin, L.T.

    1979-01-01

    The Radioactive Materials Analytical Laboratory was completed 15 years ago and has been used since as an analytical chemistry support lab for reactor, fuel development, and reprocessing programs. Additions have been made to the building on two occasions, and a third addition is planned for the future. Major maintenance items include replacement of ZnBr/sub 2/ windows, cleanup of lead glass windows, and servicing of the intercell conveyor. An upgrading program, now in progress, includes construction of new hot-cell instrumentation and the installation of new equipment such as an x-ray fluorescence analyzer and a spark source mass spectrometer.

  8. Analytical laboratory quality audits

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, William D.

    2001-06-11

    Analytical Laboratory Quality Audits are designed to improve laboratory performance. The success of the audit, as for many activities, is based on adequate preparation, precise performance, well documented and insightful reporting, and productive follow-up. Adequate preparation starts with definition of the purpose, scope, and authority for the audit and the primary standards against which the laboratory quality program will be tested. The scope and technical processes involved lead to determining the needed audit team resources. Contact is made with the auditee and a formal audit plan is developed, approved and sent to the auditee laboratory management. Review of the auditee's quality manual, key procedures and historical information during preparation leads to better checklist development and more efficient and effective use of the limited time for data gathering during the audit itself. The audit begins with the opening meeting that sets the stage for the interactions between the audit team and the laboratory staff. Arrangements are worked out for the necessary interviews and examination of processes and records. The information developed during the audit is recorded on the checklists. Laboratory management is kept informed of issues during the audit so there are no surprises at the closing meeting. The audit report documents whether the management control systems are effective. In addition to findings of nonconformance, positive reinforcement of exemplary practices provides balance and fairness. Audit closure begins with receipt and evaluation of proposed corrective actions from the nonconformances identified in the audit report. After corrective actions are accepted, their implementation is verified. Upon closure of the corrective actions, the audit is officially closed.

  9. ANALYTICAL MICROBIOLOGY LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains equipment that performs a broad array of microbiological analyses for pathogenic and spoilage microorganisms. It performs challenge studies...

  10. Remote Electro-Analytical Laboratory

    Directory of Open Access Journals (Sweden)

    Ratnanjali Gandhi

    2011-02-01

    Full Text Available Remote Laboratories are web based distance learning laboratories that have immense potential to disseminate technology in the area of practical science. These laboratories can be accessed through Internet. In the present paper, we will be discussing our experiences in setting up a remote analytical laboratory at our center. Further, we will discuss remote experiments in the area of electro-analytical chemistry & colorimetry and their role in strengthening the system of science education.

  11. Remote Electro-Analytical Laboratory

    OpenAIRE

    Ratnanjali Gandhi; Rehan Mohd; Soami Satsangee

    2011-01-01

    Remote Laboratories are web based distance learning laboratories that have immense potential to disseminate technology in the area of practical science. These laboratories can be accessed through Internet. In the present paper, we will be discussing our experiences in setting up a remote analytical laboratory at our center. Further, we will discuss remote experiments in the area of electro-analytical chemistry & colorimetry and their role in strengthening the system of science educat...

  12. Analytical Chemistry Laboratory

    Science.gov (United States)

    Anderson, Mark

    2013-01-01

    The Analytical Chemistry and Material Development Group maintains a capability in chemical analysis, materials R&D failure analysis and contamination control. The uniquely qualified staff and facility support the needs of flight projects, science instrument development and various technical tasks, as well as Cal Tech.

  13. 77 FR 16551 - Standards for Private Laboratory Analytical Packages and Introduction to Laboratory Related...

    Science.gov (United States)

    2012-03-21

    ... HUMAN SERVICES Food and Drug Administration Standards for Private Laboratory Analytical Packages and Introduction to Laboratory Related Portions of the Food Modernization Safety Act for Private Laboratory... Administration (FDA) is announcing two meetings entitled ``Standards for Private Laboratory Analytical...

  14. Wageningen Evaluating Programmes for Analytical Laboratories (WEPAL).

    Science.gov (United States)

    van Dijk, D; Houba, V J

    1999-03-01

    The paper describes three of the Wageningen Evaluating Programmes for Analytical Laboratories (WEPAL). These include the analyses of numerous compounds and elements and different parameters such as inorganic chemical composition, organic matter, polycyclic hydrocarbons (PAH), polychlorinated biphenyls (PCB), organochlorine pesticides, some herbicides, heavy metals, particle size, and so on in soil, sediment, compost, manure, and sludge. One programme includes the analysis of inorganic chemical composition, nutritional values, and selected vitamins and amino acids in plant samples. Finally, the paper describes how the results are reported and statistically evaluated.

  15. Analytical laboratory and mobile sampling platform

    Energy Technology Data Exchange (ETDEWEB)

    Stetzenbach, K.; Smiecinski, A.

    1996-04-30

    This is the final report for the Analytical Laboratory and Mobile Sampling Platform project. This report contains only major findings and conclusions resulting from this project. Detailed reports of all activities performed for this project were provided to the Project Office every quarter since the beginning of the project. This report contains water chemistry data for samples collected in the Nevada section of Death Valley National Park (Triangle Area Springs), Nevada Test Site springs, Pahranagat Valley springs, Nevada Test Site wells, Spring Mountain springs and Crater Flat and Amargosa Valley wells.

  16. Clinical laboratory analytics: Challenges and promise for an emerging discipline

    Directory of Open Access Journals (Sweden)

    Brian H Shirts

    2015-01-01

    Full Text Available The clinical laboratory is a major source of health care data. Increasingly these data are being integrated with other data to inform health system-wide actions meant to improve diagnostic test utilization, service efficiency, and "meaningful use." The Academy of Clinical Laboratory Physicians and Scientists hosted a satellite meeting on clinical laboratory analytics in conjunction with their annual meeting on May 29, 2014 in San Francisco. There were 80 registrants for the clinical laboratory analytics meeting. The meeting featured short presentations on current trends in clinical laboratory analytics and several panel discussions on data science in laboratory medicine, laboratory data and its role in the larger healthcare system, integrating laboratory analytics, and data sharing for collaborative analytics. One main goal of meeting was to have an open forum of leaders that work with the "big data" clinical laboratories produce. This article summarizes the proceedings of the meeting and content discussed.

  17. Guide to Savannah River Laboratory Analytical Services Group

    Energy Technology Data Exchange (ETDEWEB)

    1990-04-01

    The mission of the Analytical Services Group (ASG) is to provide analytical support for Savannah River Laboratory Research and Development Programs using onsite and offsite analytical labs as resources. A second mission is to provide Savannah River Site (SRS) operations with analytical support for nonroutine material characterization or special chemical analyses. The ASG provides backup support for the SRS process control labs as necessary.

  18. Analytical Chemistry Laboratory progress report for FY 1985

    Energy Technology Data Exchange (ETDEWEB)

    Green, D.W.; Heinrich, R.R.; Jensen, K.J.

    1985-12-01

    The Analytical Chemistry Laboratory is a full-cost-recovery service center, with the primary mission of providing a broad range of technical support services to the scientific and engineering programs at ANL. In addition, ACL conducts a research program in analytical chemistry, works on instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL handles a wide range of analytical problems, from routine standard analyses to unique problems that require significant development of methods and techniques. The purpose of this report is to summarize the technical and administrative activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year 1985 (October 1984 through September 1985). This is the second annual report for the ACL. 4 figs., 1 tab.

  19. Analytical Chemistry Laboratory progress report for FY 1999

    Energy Technology Data Exchange (ETDEWEB)

    Green, D. W.; Boparai, A. S.; Bowers, D. L.; Graczyk, D. G.

    2000-06-15

    This report summarizes the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1999 (October 1998 through September 1999). This annual progress report, which is the sixteenth in this series for the ACL, describes effort on continuing projects, work on new projects, and contributions of the ACL staff to various programs at ANL.

  20. Analytical Chemistry Laboratory progress report for FY 1998.

    Energy Technology Data Exchange (ETDEWEB)

    Boparai, A. S.; Bowers, D. L.; Graczyk, D. G.; Green, D. W.; Lindahl, P. C.

    1999-03-29

    This report summarizes the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1998 (October 1997 through September 1998). This annual progress report, which is the fifteenth in this series for the ACL, describes effort on continuing projects, work on new projects, and contributions of the ACL staff to various programs at ANL.

  1. Pre-analytical workstations: a tool for reducing laboratory errors.

    Science.gov (United States)

    Da Rin, Giorgio

    2009-06-01

    Laboratory testing, a highly complex process commonly called the total testing process (TTP), is usually subdivided into three traditional (pre-, intra-, and post-) analytical phases. The majority of errors in TTP originate in the pre-analytical phase, being due to individual or system design defects. In order to reduce errors in TTP, the pre-analytical phase should therefore be prioritized. In addition to developing procedures, providing training, improving interdepartmental cooperation, information technology and robotics may be a tool to reduce errors in specimen collection and pre-analytical sample handling. It has been estimated that >2000 clinical laboratories worldwide use total or subtotal automation supporting pre-analytic activities, with a high rate of increase compared to 2007; the need to reduce errors seems to be the catalyst for increasing the use of robotics. Automated systems to prevent medical personnel from drawing blood from the wrong patient were introduced commercially in the early 1990s. Correct patient identification and test tube labelling before phlebotomy are of extreme importance for patient safety in TTP, but currently few laboratories are interested in such products. At San Bassiano hospital, the implementation of advanced information technology and robotics in the pre-analytical phase (specimen collection and pre-analytical sample handling) have improved accuracy, and clinical efficiency of the laboratory process and created a TTP that minimizes errors.

  2. Analytical Chemistry Laboratory. Progress report for FY 1996

    Energy Technology Data Exchange (ETDEWEB)

    Green, D.W.; Boparai, A.S.; Bowers, D.L.

    1996-12-01

    The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1996. This annual report is the thirteenth for the ACL. It describes effort on continuing and new projects and contributions of the ACL staff to various programs at ANL. The ACL operates in the ANL system as a full-cost-recovery service center, but has a mission that includes a complementary research and development component: The Analytical Chemistry Laboratory will provide high-quality, cost-effective chemical analysis and related technical support to solve research problems of our clients -- Argonne National Laboratory, the Department of Energy, and others -- and will conduct world-class research and development in analytical chemistry and its applications. Because of the diversity of research and development work at ANL, the ACL handles a wide range of analytical chemistry problems. Some routine or standard analyses are done, but the ACL usually works with commercial laboratories if our clients require high-volume, production-type analyses. It is common for ANL programs to generate unique problems that require significant development of methods and adaption of techniques to obtain useful analytical data. Thus, much of the support work done by the ACL is very similar to our applied analytical chemistry research.

  3. Clinical laboratory analytics: Challenges and promise for an emerging discipline

    OpenAIRE

    Brian H Shirts; Jackson, Brian R.; Baird, Geoffrey S.; Baron, Jason M.; Bryan Clements; Ricky Grisson; Ronald George Hauser; Taylor, Julie R.; Enrique Terrazas; Brad Brimhall

    2015-01-01

    The clinical laboratory is a major source of health care data. Increasingly these data are being integrated with other data to inform health system-wide actions meant to improve diagnostic test utilization, service efficiency, and "meaningful use." The Academy of Clinical Laboratory Physicians and Scientists hosted a satellite meeting on clinical laboratory analytics in conjunction with their annual meeting on May 29, 2014 in San Francisco. There were 80 registrants for the clinical laborator...

  4. Infrared Microscopy In An Industrial Analytical Laboratory

    Science.gov (United States)

    Strawn, A. W.

    1989-12-01

    This paper describes the chemical identification of solid samples in the size range of 8-250um in diameter. The samples are usually inhomogeneous and range from polymer inclusions to fibres. While scanning electron and optical microscopy are usually the first line of analysis for such samples, they cannot yield chemical identification when the sample is organic. A combination of infrared microscopy and spectral library searching provides a powerful technique in the industrial laboratory and examples are shown of polymer inclusions, laminates, fibres and filter deposits. The spectra were obtained using a Spectra-Tech IR Plan Microscope coupled to the external port of a Nicolet 5DXC FTIR spectrometer whose main compartment houses an MTEC Photoacoustic (PAS) Cell. The complementary facets of PAS and infrared microscopy are also highlighted.

  5. Pre-analytical phase in clinical chemistry laboratory

    Directory of Open Access Journals (Sweden)

    Neogi SS

    2016-07-01

    Full Text Available The laboratory testing process is divided into the pre-analytical, analytical and post-analytical phases. For obtaining reliable test results, the prevention and detection of errors at all steps is required. While analytical standards have been developed by recognized quality control criteria, there is a scarcity in the development of standards for the preanalytical phase. This phase is most prone to errors as the steps involved are directly dependent on humans and are out of direct control of the laboratory. Such errors in preanalytical stage often only become apparent in the analytical or post-analytical phase. The development of a pre-analytical quality manual is essential in achieving total quality control. Correct practices and strategies of error prevention can reduce preanalytical errors. This review focuses on prevention of pre-analytical errors that occur while collecting a specimen of blood, urine and cerebrospinal fluid. Most of these can be easily prevented with understanding and education of the personnel involved in and responsible for executing this crucial pre-analytical phase.

  6. Analytical Chemistry Laboratory, progress report for FY 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1993 (October 1992 through September 1993). This annual report is the tenth for the ACL and describes continuing effort on projects, work on new projects, and contributions of the ACL staff to various programs at ANL. The Analytical Chemistry Laboratory is a full-cost-recovery service center, with the primary mission of providing a broad range of analytical chemistry support services to the scientific and engineering programs at ANL. The ACL also has research programs in analytical chemistry, conducts instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL handles a wide range of analytical problems. Some routine or standard analyses are done, but it is common for the Argonne programs to generate unique problems that require development or modification of methods and adaption of techniques to obtain useful analytical data. The ACL is administratively within the Chemical Technology Division (CMT), its principal ANL client, but provides technical support for many of the technical divisions and programs at ANL. The ACL has four technical groups--Chemical Analysis, Instrumental Analysis, Organic Analysis, and Environmental Analysis--which together include about 45 technical staff members. Talents and interests of staff members cross the group lines, as do many projects within the ACL.

  7. Idaho National Engineering Laboratory analytical services performance evaluation plan

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, J.M.; Sailer, S.J.; Anderson, D.A.

    1994-03-01

    The Idaho National Engineering Laboratory`s (INEL`s) Sample Management Office (SMO) conducts a Performance Evaluation Program that ensures that data of known quality are supplied by the analytical. chemistry service organizations with which the INEL contracts. The Analytical Services Performance Evaluation Plan documents the routine monitoring and assessment of suppliers conducted by the SMO, and it describes the procedures that are followed to ensure that suppliers meet all appropriate requirements. Because high-quality analytical support is vital to the success of DOE Environmental Management programs at the INEL, the performance of organizations providing these services must be routinely monitored and assessed. Analytical disciplines for which performance is monitored include metals, organics, radiochemical, and miscellaneous classical analysis methods.

  8. Analytical chemistry laboratory. Progress report for FY 1997

    Energy Technology Data Exchange (ETDEWEB)

    Green, D.W.; Boparai, A.S.; Bowers, D.L. [and others

    1997-12-01

    The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1997 (October 1996 through September 1997). This annual progress report is the fourteenth in this series for the ACL, and it describes continuing effort on projects, work on new projects, and contributions of the ACL staff to various programs at ANL.

  9. Analytical Chemistry Laboratory Progress Report for FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    Green, D.W.; Boparai, A.S.; Bowers, D.L. [and others

    1994-12-01

    The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1994 (October 1993 through September 1994). This annual report is the eleventh for the ACL and describes continuing effort on projects, work on new projects, and contributions of the ACL staff to various programs at ANL. The Analytical Chemistry Laboratory is a full-cost-recovery service center, with the primary mission of providing a broad range of analytical chemistry support services to the scientific and engineering programs at ANL. The ACL also has a research program in analytical chemistry, conducts instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL handles a wide range of analytical problems. Some routine or standard analyses are done, but it is common for the Argonne programs to generate unique problems that require significant development of methods and adaption of techniques to obtain useful analytical data. The ACL has four technical groups -- Chemical Analysis, Instrumental Analysis, Organic Analysis, and Environmental Analysis -- which together include about 45 technical staff members. Talents and interests of staff members cross the group lines, as do many projects within the ACL. The Chemical Analysis Group uses wet- chemical and instrumental methods for elemental, compositional, and isotopic determinations in solid, liquid, and gaseous samples and provides specialized analytical services. Major instruments in this group include an ion chromatograph (IC), an inductively coupled plasma/atomic emission spectrometer (ICP/AES), spectrophotometers, mass spectrometers (including gas-analysis and thermal-ionization mass spectrometers), emission spectrographs, autotitrators, sulfur and carbon determinators, and a kinetic phosphorescence uranium analyzer.

  10. Summative Mass Analysis of Algal Biomass - Integration of Analytical Procedures: Laboratory Analytical Procedure (LAP)

    Energy Technology Data Exchange (ETDEWEB)

    Laurens, L. M. L.

    2013-12-01

    This procedure guides the integration of laboratory analytical procedures to measure algal biomass constituents in an unambiguous manner and ultimately achieve mass balance closure for algal biomass samples. Many of these methods build on years of research in algal biomass analysis.

  11. Analytical Chemistry Laboratory progress report for FY 1984

    Energy Technology Data Exchange (ETDEWEB)

    Green, D.W.; Heinrich, R.R.; Jensen, K.J.; Stetter, J.R.

    1985-03-01

    Technical and administrative activities of the Analytical Chemistry Laboratory (ACL) are reported for fiscal year 1984. The ACL is a full-cost-recovery service center, with the primary mission of providing a broad range of technical support services to the scientific and engineering programs at ANL. In addition, ACL conducts a research program in analytical chemistry, works on instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL is administratively within the Chemical Technology Division, the principal user, but provides technical support for all of the technical divisions and programs at ANL. The ACL has three technical groups - Chemical Analysis, Instrumental Analysis, and Organic Analysis. Under technical activities 26 projects are briefly described. Under professional activities, a list is presented for publications and reports, oral presentations, awards and meetings attended. 6 figs., 2 tabs.

  12. The European Network of Analytical and Experimental Laboratories for Geosciences

    Science.gov (United States)

    Freda, Carmela; Funiciello, Francesca; Meredith, Phil; Sagnotti, Leonardo; Scarlato, Piergiorgio; Troll, Valentin R.; Willingshofer, Ernst

    2013-04-01

    Integrating Earth Sciences infrastructures in Europe is the mission of the European Plate Observing System (EPOS).The integration of European analytical, experimental, and analogue laboratories plays a key role in this context and is the task of the EPOS Working Group 6 (WG6). Despite the presence in Europe of high performance infrastructures dedicated to geosciences, there is still limited collaboration in sharing facilities and best practices. The EPOS WG6 aims to overcome this limitation by pushing towards national and trans-national coordination, efficient use of current laboratory infrastructures, and future aggregation of facilities not yet included. This will be attained through the creation of common access and interoperability policies to foster and simplify personnel mobility. The EPOS ambition is to orchestrate European laboratory infrastructures with diverse, complementary tasks and competences into a single, but geographically distributed, infrastructure for rock physics, palaeomagnetism, analytical and experimental petrology and volcanology, and tectonic modeling. The WG6 is presently organizing its thematic core services within the EPOS distributed research infrastructure with the goal of joining the other EPOS communities (geologists, seismologists, volcanologists, etc...) and stakeholders (engineers, risk managers and other geosciences investigators) to: 1) develop tools and services to enhance visitor programs that will mutually benefit visitors and hosts (transnational access); 2) improve support and training activities to make facilities equally accessible to students, young researchers, and experienced users (training and dissemination); 3) collaborate in sharing technological and scientific know-how (transfer of knowledge); 4) optimize interoperability of distributed instrumentation by standardizing data collection, archive, and quality control standards (data preservation and interoperability); 5) implement a unified e-Infrastructure for data

  13. 78 FR 4170 - License Amendment Request for Analytical Bio-Chemistry Laboratories, Inc., Columbia, MO

    Science.gov (United States)

    2013-01-18

    ... COMMISSION License Amendment Request for Analytical Bio-Chemistry Laboratories, Inc., Columbia, MO AGENCY... issuance of a license amendment to Materials License No. 24-13365-01 issued to Analytical Bio-Chemistry... accession numbers are: 1. Analytical Bio-Chemistry Laboratories, Inc., Licensee amendment request...

  14. The State of Analytical Instruments in Some Environmental Pollution Control Laboratories in Nigeria

    Directory of Open Access Journals (Sweden)

    Dr. (Mrs. Bertha Abdu Danja

    2016-09-01

    Full Text Available The state of the environmental laboratories involved in monitoring environmental pollution control in Nigeria has been studied in this research. The research was undertaken by visiting four analytical laboratories involved in environmental pollution control in Nigeria. The analytical laboratories visited are those of Nigerian National Petroleum Corporation (NNPC Kaduna, Ashaka cement factory, regional laboratory of the Federal Ministry of Water Resources Gombe, and the National Reference laboratory Lagos. In these laboratories results were collected in the laboratories, interviews were carried out and analytical instruments available were documented. It was discovered that, in these laboratories many standard analytical instruments needed for quality environmental pollution control and monitoring are lacking. Comparison of analytical instruments found in these laboratories with those found in literature revealed that many needed analytical instruments are missing. It is the position of this work that the gap between the environmental analytical instruments found in literature and that found in the research laboratories is very large and calls for concern.

  15. Manual of analytical methods for the Industrial Hygiene Chemistry Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Greulich, K.A.; Gray, C.E. (comp.)

    1991-08-01

    This Manual is compiled from techniques used in the Industrial Hygiene Chemistry Laboratory of Sandia National Laboratories in Albuquerque, New Mexico. The procedures are similar to those used in other laboratories devoted to industrial hygiene practices. Some of the methods are standard; some, modified to suit our needs; and still others, developed at Sandia. The authors have attempted to present all methods in a simple and concise manner but in sufficient detail to make them readily usable. It is not to be inferred that these methods are universal for any type of sample, but they have been found very reliable for the types of samples mentioned.

  16. Contributions of Analytical Chemistry to the Clinical Laboratory.

    Science.gov (United States)

    Skogerboe, Kristen J.

    1988-01-01

    Highlights several analytical techniques that are being used in state-of-the-art clinical labs. Illustrates how other advances in instrumentation may contribute to clinical chemistry in the future. Topics include: biosensors, polarization spectroscopy, chemiluminescence, fluorescence, photothermal deflection, and chromatography in clinical…

  17. Integration of Environmental Analytical Chemistry with Environmental Law: The Development of a Problem-Based Laboratory.

    Science.gov (United States)

    Cancilla, Devon A.

    2001-01-01

    Introduces an undergraduate level problem-based analytical chemistry laboratory course integrated with an environmental law course. Aims to develop an understanding among students on the use of environmental indicators for environmental evaluation. (Contains 30 references.) (YDS)

  18. ASVCP quality assurance guidelines: control of general analytical factors in veterinary laboratories.

    Science.gov (United States)

    Flatland, Bente; Freeman, Kathy P; Friedrichs, Kristen R; Vap, Linda M; Getzy, Karen M; Evans, Ellen W; Harr, Kendal E

    2010-09-01

    Owing to lack of governmental regulation of veterinary laboratory performance, veterinarians ideally should demonstrate a commitment to self-monitoring and regulation of laboratory performance from within the profession. In response to member concerns about quality management in veterinary laboratories, the American Society for Veterinary Clinical Pathology (ASVCP) formed a Quality Assurance and Laboratory Standards (QAS) committee in 1996. This committee recently published updated and peer-reviewed Quality Assurance Guidelines on the ASVCP website. The Quality Assurance Guidelines are intended for use by veterinary diagnostic laboratories and veterinary research laboratories that are not covered by the US Food and Drug Administration Good Laboratory Practice standards (Code of Federal Regulations Title 21, Chapter 58). The guidelines have been divided into 3 reports on 1) general analytic factors for veterinary laboratory performance and comparisons, 2) hematology and hemostasis, and 3) clinical chemistry, endocrine assessment, and urinalysis. This report documents recommendations for control of general analytical factors within veterinary clinical laboratories and is based on section 2.1 (Analytical Factors Important In Veterinary Clinical Pathology, General) of the newly revised ASVCP QAS Guidelines. These guidelines are not intended to be all-inclusive; rather, they provide minimum guidelines for quality assurance and quality control for veterinary laboratory testing. It is hoped that these guidelines will provide a basis for laboratories to assess their current practices, determine areas for improvement, and guide continuing professional development and education efforts.

  19. MODULAR ANALYTICS: A New Approach to Automation in the Clinical Laboratory

    OpenAIRE

    Horowitz, Gary L.; Zaman, Zahur; Blanckaert, Norbert J. C.; Chan, Daniel W.; Dubois, Jeffrey A.; Golaz, Olivier; Mensi, Noury; Keller, Franz; Stolz, Herbert; Klingler, Karl; Marocchi, Alessandro; Prencipe, Lorenzo; McLawhon, Ronald W.; Nilsen, Olaug L.; Oellerich, Michael

    2005-01-01

    MODULAR ANALYTICS (Roche Diagnostics) (MODULAR ANALYTICS, Elecsys and Cobas Integra are trademarks of a member of the Roche Group) represents a new approach to automation for the clinical chemistry laboratory. It consists of a control unit, a core unit with a bidirectional multitrack rack transportation system, and three distinct kinds of analytical modules: an ISE module, a P800 module (44 photometric tests, throughput of up to 800 tests/h), and a D2400 module (16 photometric tests, throughp...

  20. A Comprehensive Microfluidics Device Construction and Characterization Module for the Advanced Undergraduate Analytical Chemistry Laboratory

    Science.gov (United States)

    Piunno, Paul A. E.; Zetina, Adrian; Chu, Norman; Tavares, Anthony J.; Noor, M. Omair; Petryayeva, Eleonora; Uddayasankar, Uvaraj; Veglio, Andrew

    2014-01-01

    An advanced analytical chemistry undergraduate laboratory module on microfluidics that spans 4 weeks (4 h per week) is presented. The laboratory module focuses on comprehensive experiential learning of microfluidic device fabrication and the core characteristics of microfluidic devices as they pertain to fluid flow and the manipulation of samples.…

  1. Standard guide for establishing a quality assurance program for analytical chemistry laboratories within the nuclear industry

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2006-01-01

    1.1 This guide covers the establishment of a quality assurance (QA) program for analytical chemistry laboratories within the nuclear industry. Reference to key elements of ANSI/ISO/ASQC Q9001, Quality Systems, provides guidance to the functional aspects of analytical laboratory operation. When implemented as recommended, the practices presented in this guide will provide a comprehensive QA program for the laboratory. The practices are grouped by functions, which constitute the basic elements of a laboratory QA program. 1.2 The essential, basic elements of a laboratory QA program appear in the following order: Section Organization 5 Quality Assurance Program 6 Training and Qualification 7 Procedures 8 Laboratory Records 9 Control of Records 10 Control of Procurement 11 Control of Measuring Equipment and Materials 12 Control of Measurements 13 Deficiencies and Corrective Actions 14

  2. [The analytic quality in laboratory medicine: problems and perspectives (a lecture)].

    Science.gov (United States)

    Émanuél', A V; Ivanov, G A; Émanuél', Iu V

    2014-03-01

    The article considers the structure of analytical errors in clinical diagnostic laboratory analysis from the position of GOST R ISO 15189-2009 "Laboratories of medicine. Particular requirements to quality and competence". The key value of metrologic traceability of analyses is emphasized. The role of official standard patterns, control materials and statistical methods applied in quality analysis are discussed. The international experience and applied methodical procedures to implement requirements of ISO 15189 concerning validation and verification of analytical quality are presented. The approaches of protocols E3 23-A, ER 15-A2, N59-A in the sphere of USA laboratory medicine developed by the institute of clinical and laboratory standards are demonstrated. The review of referent patterns and methods is given. The problem of optimization of requirements to quality of production for laboratory diagnostic is discussed. The expedience of organization of the National institute of laboratory standards is substantiated.

  3. Analytical performance specifications based on how clinicians use laboratory tests. Experiences from a post-analytical external quality assessment programme.

    Science.gov (United States)

    Thue, Geir; Sandberg, Sverre

    2015-05-01

    Analytical performance specifications can be based on three different models: the effect of analytical performance on clinical outcome, based on components of biological variation of the measurand or based on state-of-the-art. Models 1 and 3 may to some degree be combined by using case histories presented to a large number of clinicians. The Norwegian Quality Improvement of Primary Care Laboratories (Noklus) has integrated vignettes in its external quality assessment programme since 1991, focusing on typical clinical situations in primary care. Haemoglobin, erythrocyte sedimentation rate (ESR), HbA1c, glucose, u-albumin, creatinine/estimated glomerular filtration rate (eGFR), and Internationl Normalised Ratio (INR) have been evaluated focusing on critical differences in test results, i.e., a change from a previous result that will generate an "action" such as a change in treatment or follow-up of the patient. These critical differences, stated by physicians, can translate into reference change values (RCVs) and assumed analytical performance can be calculated. In general, assessments of RCVs and therefore performance specifications vary both within and between groups of doctors, but with no or minor differences regarding specialisation, age or sex of the general practitioner. In some instances state-of-the-art analytical performance could not meet clinical demands using 95% confidence, whereas clinical demands were met using 80% confidence in nearly all instances. RCVs from vignettes should probably not be used on their own as a basis for setting analytical performance specifications, since clinicians seem "uninformed" regarding important principles. They could rather be used as a background for focus groups of "informed" physicians in discussions of performance specifications tailored to "typical" clinical situations.

  4. Liquid-Liquid Extraction of Insecticides from Juice: An Analytical Chemistry Laboratory Experiment

    Science.gov (United States)

    Radford, Samantha A.; Hunter, Ronald E., Jr.; Barr, Dana Boyd; Ryan, P. Barry

    2013-01-01

    A laboratory experiment was developed to target analytical chemistry students and to teach them about insecticides in food, sample extraction, and cleanup. Micro concentrations (sub-microgram/mL levels) of 12 insecticides spiked into apple juice samples are extracted using liquid-liquid extraction and cleaned up using either a primary-secondary…

  5. Determination of Mercury in Milk by Cold Vapor Atomic Fluorescence: A Green Analytical Chemistry Laboratory Experiment

    Science.gov (United States)

    Armenta, Sergio; de la Guardia, Miguel

    2011-01-01

    Green analytical chemistry principles were introduced to undergraduate students in a laboratory experiment focused on determining the mercury concentration in cow and goat milk. In addition to traditional goals, such as accuracy, precision, sensitivity, and limits of detection in method selection and development, attention was paid to the…

  6. Useful measures and models for analytical quality management in medical laboratories.

    Science.gov (United States)

    Westgard, James O

    2016-02-01

    The 2014 Milan Conference "Defining analytical performance goals 15 years after the Stockholm Conference" initiated a new discussion of issues concerning goals for precision, trueness or bias, total analytical error (TAE), and measurement uncertainty (MU). Goal-setting models are critical for analytical quality management, along with error models, quality-assessment models, quality-planning models, as well as comprehensive models for quality management systems. There are also critical underlying issues, such as an emphasis on MU to the possible exclusion of TAE and a corresponding preference for separate precision and bias goals instead of a combined total error goal. This opinion recommends careful consideration of the differences in the concepts of accuracy and traceability and the appropriateness of different measures, particularly TAE as a measure of accuracy and MU as a measure of traceability. TAE is essential to manage quality within a medical laboratory and MU and trueness are essential to achieve comparability of results across laboratories. With this perspective, laboratory scientists can better understand the many measures and models needed for analytical quality management and assess their usefulness for practical applications in medical laboratories.

  7. Integrating Bio-Inorganic and Analytical Chemistry into an Undergraduate Biochemistry Laboratory

    Science.gov (United States)

    Erasmus, Daniel J.; Brewer, Sharon E.; Cinel, Bruno

    2015-01-01

    Undergraduate laboratories expose students to a wide variety of topics and techniques in a limited amount of time. This can be a challenge and lead to less exposure to concepts and activities in bio-inorganic chemistry and analytical chemistry that are closely-related to biochemistry. To address this, we incorporated a new iron determination by…

  8. Understanding Fluorescence Measurements through a Guided-Inquiry and Discovery Experiment in Advanced Analytical Laboratory

    Science.gov (United States)

    Wilczek-Vera, Grazyna; Salin, Eric Dunbar

    2011-01-01

    An experiment on fluorescence spectroscopy suitable for an advanced analytical laboratory is presented. Its conceptual development used a combination of the expository and discovery styles. The "learn-as-you-go" and direct "hands-on" methodology applied ensures an active role for a student in the process of visualization and discovery of concepts.…

  9. The Efficacy of Problem-Based Learning in an Analytical Laboratory Course for Pre-Service Chemistry Teachers

    Science.gov (United States)

    Yoon, Heojeong; Woo, Ae Ja; Treagust, David; Chandrasegaran, A. L.

    2014-01-01

    The efficacy of problem-based learning (PBL) in an analytical chemistry laboratory course was studied using a programme that was designed and implemented with 20 students in a treatment group over 10 weeks. Data from 26 students in a traditional analytical chemistry laboratory course were used for comparison. Differences in the creative thinking…

  10. Analytical Laboratory Science on the 2009 Mars Science Laboratory (MSL) Mission

    Science.gov (United States)

    Mahaffy, P. R.

    2005-01-01

    The Odyssey Missions orbital maps of near surface ice abundance using neutron spectroscopy (Boynton et al., 2002), the Mars Exploration Rover s confirmation of aqueous processing (Squyres et al., 2004), and the Mars Express detailed infrared maps of specific mineral types that were likely formed in aqueous environments (Bibring et al., 2005) have dramatically expanded our tool set for understanding of aqueous processes on Mars. The 2009 Mars Science Laboratory is designed to extend the "follow the water" crosscutting theme of the Mars Exploration Program toward an even more detailed exploration of habitability - the potential of the Mars environment to support life. The next steps in understanding the habitability of Mars are a more detailed in situ analysis of the chemical state of elements such as C, H, O, N, S, P, Ca, and Fe that are essential for terrestrial life. Of particular interest are experiments that establish definitive mineralogy for a wider range of compounds and those that implement a more comprehensive and sensitive search for organic molecules both in the atmosphere and in surface or near surface rocks, soils, and fines. The recent reports of atmospheric methane in the Martian atmosphere make the organics exploration even more compelling. The substantial mass and power resources of MSL combined with its mobility and powerful sample acquisition and processing tools will enable it to locate a variety of near-surface samples and analyze these in some detail. NASA is presently considering the possibility of landing a second MSL rover in 2011.

  11. Integrating bio-inorganic and analytical chemistry into an undergraduate biochemistry laboratory.

    Science.gov (United States)

    Erasmus, Daniel J; Brewer, Sharon E; Cinel, Bruno

    2015-01-01

    Undergraduate laboratories expose students to a wide variety of topics and techniques in a limited amount of time. This can be a challenge and lead to less exposure to concepts and activities in bio-inorganic chemistry and analytical chemistry that are closely-related to biochemistry. To address this, we incorporated a new iron determination by atomic absorption spectroscopy exercise as part of a five-week long laboratory-based project on the purification of myoglobin from beef. Students were required to prepare samples for chemical analysis, operate an atomic absorption spectrophotometer, critically evaluate their iron data, and integrate these data into a study of myoglobin.

  12. Analytical progresses of the International Olympic Committee and World Anti-Doping Agency Olympic laboratories.

    Science.gov (United States)

    Georgakopoulos, Costas; Saugy, Martial; Giraud, Sylvain; Robinson, Neil; Alsayrafi, Mohammed

    2012-07-01

    The Summer Olympic Games constitute the biggest concentration of human sports and activities in a particular place and time since 776 BCE, when the written history of the Olympic Games in Olympia began. Summer and Winter Olympic anti-doping laboratories, accredited by the International Olympic Committee in the past and the World Anti-Doping Agency in the present times, acquire worldwide interest to apply all new analytical advancements in the fight against doping in sports, hoping that this major human event will not become dirty by association with this negative phenomenon. This article summarizes the new analytical progresses, technologies and knowledge used by the Olympic laboratories, which for the vast majority of them are, eventually, incorporated into routine anti-doping analysis.

  13. Comparison between laboratory measurements, simulations, and analytical predictions of the transverse wall impedance at low frequencies

    CERN Document Server

    Roncarolo, F; Kroyer, T; Metral, E; Mounet, N; Salvant, B; Zotter, B

    2009-01-01

    The prediction of the transverse wall beam impedance at the first unstable betatron line (8 kHz) of the CERN Large Hadron Collider (LHC) is of paramount importance for understanding and controlling the related coupled-bunch instabilities. Until now only novel analytical formulas were available at this frequency. Recently, laboratory measurements and numerical simulations were performed to cross-check the analytical predictions. The experimental results based on the measurement of the variation of a probe coil inductance in the presence of (i) sample graphite plates, (ii) stand-alone LHC collimator jaws, and (iii) a full LHC collimator assembly are presented in detail. The measurement results are compared to both analytical theories and simulations. In addition, the consequences for the understanding of the LHC impedance are discussed.

  14. Mass and emission spectrometry in the Analytical Chemistry Division of Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D.H. (ed.)

    1978-11-01

    The capabilities of the Mass and Emission Spectrometry Section of the Analytical Chemistry Division of Oak Ridge National Laboratory are described. Many different areas of mass spectrometric expertise are represented in the section: gas analysis, high abundance sensitivity measurements, high- and low-resolution organic analyses, spark source trace constituent analysis, and ion microprobe analysis of surfaces. These capabilities are complemented by emission spectrometry. The instruments are described along with a few applications, some of which are unique.

  15. ELAN - expert system supported information and management system for analytical laboratories. ELAN - Expertengestuetztes Informationssystem fuer die Laboranalytik

    Energy Technology Data Exchange (ETDEWEB)

    Orth, H.; Zilly, G.

    1990-05-01

    The demand for high efficiency and short response time calls for the use of computer support in chemico-analytical laboratories. This is usually achieved by laboratory information and management systems covering the three levels of analytical instrument automation, laboratory operation support and laboratory management. The management component of the systems implemented up to now suffers from a lack of flexibility as far as unforeseen analytical investigations outside the laboratory routine work are concerned. Another drawback is the lack of adaptability with respect to structural changes in laboratory organization. It can be eliminated by the application of expert system structures and methods for the implementation of this system level. The ELAN laboratory information and management system has been developed on the basis of this concept. (orig.).

  16. Development of analytical methodologies to assess recalcitrant pesticide bioremediation in biobeds at laboratory scale.

    Science.gov (United States)

    Rivero, Anisleidy; Niell, Silvina; Cerdeiras, M Pía; Heinzen, Horacio; Cesio, María Verónica

    2016-06-01

    To assess recalcitrant pesticide bioremediation it is necessary to gradually increase the complexity of the biological system used in order to design an effective biobed assembly. Each step towards this effective biobed design needs a suitable, validated analytical methodology that allows a correct evaluation of the dissipation and bioconvertion. Low recovery yielding methods could give a false idea of a successful biodegradation process. To address this situation, different methods were developed and validated for the simultaneous determination of endosulfan, its main three metabolites, and chlorpyrifos in increasingly complex matrices where the bioconvertor basidiomycete Abortiporus biennis could grow. The matrices were culture media, bran, and finally a laboratory biomix composed of bran, peat and soil. The methodology for the analysis of the first evaluated matrix has already been reported. The methodologies developed for the other two systems are presented in this work. The targeted analytes were extracted from fungi growing over bran in semisolid media YNB (Yeast Nitrogen Based) with acetonitrile using shaker assisted extraction, The salting-out step was performed with MgSO4 and NaCl, and the extracts analyzed by GC-ECD. The best methodology was fully validated for all the evaluated analytes at 1 and 25mgkg(-1) yielding recoveries between 72% and 109% and RSDs methodology proved that A. biennis is able to dissipate 94% of endosulfan and 87% of chlorpyrifos after 90 days. Having assessed that A. biennis growing over bran can metabolize the studied pesticides, the next step faced was the development and validation of an analytical procedure to evaluate the analytes in a laboratory scale biobed composed of 50% of bran, 25% of peat and 25% of soil together with fungal micelium. From the different procedures assayed, only ultrasound assisted extraction with ethyl acetate allowed recoveries between 80% and 110% with RSDs <18%. Linearity, recovery, precision, matrix

  17. Improvement of analytical capabilities of neutron activation analysis laboratory at the Colombian Geological Survey

    Science.gov (United States)

    Parrado, G.; Cañón, Y.; Peña, M.; Sierra, O.; Porras, A.; Alonso, D.; Herrera, D. C.; Orozco, J.

    2016-07-01

    The Neutron Activation Analysis (NAA) laboratory at the Colombian Geological Survey has developed a technique for multi-elemental analysis of soil and plant matrices, based on Instrumental Neutron Activation Analysis (INAA) using the comparator method. In order to evaluate the analytical capabilities of the technique, the laboratory has been participating in inter-comparison tests organized by Wepal (Wageningen Evaluating Programs for Analytical Laboratories). In this work, the experimental procedure and results for the multi-elemental analysis of four soil and four plant samples during participation in the first round on 2015 of Wepal proficiency test are presented. Only elements with radioactive isotopes with medium and long half-lives have been evaluated, 15 elements for soils (As, Ce, Co, Cr, Cs, Fe, K, La, Na, Rb, Sb, Sc, Th, U and Zn) and 7 elements for plants (Br, Co, Cr, Fe, K, Na and Zn). The performance assessment by Wepal based on Z-score distributions showed that most results obtained |Z-scores| ≤ 3.

  18. Demonstrating Chemical and Analytical Concepts in the Undergraduate Laboratory Using Capillary Electrophoresis and Micellar Electrokinetic Chromatography

    Science.gov (United States)

    Palmer, Christopher P.

    1999-11-01

    This paper describes instrumental analysis laboratory exercises that utilize capillary electrophoresis and micellar electrokinetic chromatography to demonstrate several analytical and chemical principles. Alkyl parabens (4-hydroxy alkyl benzoates), which are common ingredients in cosmetic formulations, are separated by capillary electrophoresis. The electrophoretic mobilities of the parabens can be explained on the basis of their relative size. 3-Hydroxy ethylbenzoate is also separated to demonstrate the effect of substituent position on the acid dissociation constant and the effect this has on electrophoretic mobility. Homologous series of alkyl benzoates and alkyl phthalates (common plasticizers) are separated by micellar electrokinetic chromatography at four surfactant concentrations. This exercise demonstrates the separation mechanism of micellar electrokinetic chromatography, the concept of chromatographic phase ratio, and the concepts of micelle formation. A photodiode array detector is used in both exercises to demonstrate the advantages and limitations of the detector and to demonstrate the effect of pH and substituent position on the spectra of the analytes.

  19. SRC-I demonstration plant analytical laboratory methods manual. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Klusaritz, M.L.; Tewari, K.C.; Tiedge, W.F.; Skinner, R.W.; Znaimer, S.

    1983-03-01

    This manual is a compilation of analytical procedures required for operation of a Solvent-Refined Coal (SRC-I) demonstration or commercial plant. Each method reproduced in full includes a detailed procedure, a list of equipment and reagents, safety precautions, and, where possible, a precision statement. Procedures for the laboratory's environmental and industrial hygiene modules are not included. Required American Society for Testing and Materials (ASTM) methods are cited, and ICRC's suggested modifications to these methods for handling coal-derived products are provided.

  20. Laboratory Techniques in Geology: Embedding Analytical Methods into the Undergraduate Curriculum

    Science.gov (United States)

    Baedke, S. J.; Johnson, E. A.; Kearns, L. E.; Mazza, S. E.; Gazel, E.

    2014-12-01

    Paid summer REU experiences successfully engage undergraduate students in research and encourage them to continue to graduate school and scientific careers. However these programs only accommodate a limited number of students due to funding constraints, faculty time commitments, and limited access to needed instrumentation. At JMU, the Department of Geology and Environmental Science has embedded undergraduate research into the curriculum. Each student fulfilling a BS in Geology or a BA in Earth Science completes 3 credits of research, including a 1-credit course on scientific communication, 2 credits of research or internship, followed by a presentation of that research. Our department has successfully acquired many analytical instruments and now has an XRD, SEM/EDS, FTIR, handheld Raman, AA, ion chromatograph, and an IRMS. To give as many students as possible an overview to the scientific uses and operation methods for these instruments, we revived a laboratory methods course that includes theory and practical use of instrumentation at JMU, plus XRF sample preparation and analysis training at Virginia Tech during a 1-day field trip. In addition to practical training, projects included analytical concepts such as evaluating analytical vs. natural uncertainty, determining error on multiple measurements, signal-to-noise ratio, and evaluating data quality. State funding through the 4-VA program helped pay for analytical supplies and support for students to complete research projects over the summer or during the next academic year using instrumentation from the course. This course exemplifies an alternative path to broadening participation in undergraduate research and creating stronger partnerships between PUI's and research universities.

  1. Two low-level gamma spectrometry systems of the IAEA Safeguards Analytical Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Parus, J.L. [IAEA, SAL, Vienna (Austria); Raab, W. [IAEA, SAL, Vienna (Austria); Donohue, D. [IAEA, SAL, Vienna (Austria); Jansta, V. [IAEA, SAL, Vienna (Austria); Kierzek, J. [IAEA, SAL, Vienna (Austria)

    1997-03-01

    A gamma spectrometry system designed for the measurement of samples with low and medium radioactivity (activity from a few to about 10{sup 4} Bq in the energy range from 25 to 2700 keV) has been installed at the IAEA Safeguards Analytical Laboratory in Seibersdorf. The system consists of 3 low level detectors: (1) n-type coaxial Ge with 42.4% relative efficiency, 1.85 keV FWHM at 1.33 MeV (2) planar Ge with 2000 mm{sup 2} area and 20 mm thickness, 562 eV FWHM at 122 keV (3) NaI(Tl) annulus of 25.4 cm diameter and 25.4 cm height, hole diameter 90 mm. (orig./DG)

  2. Use of artificial intelligence in analytical systems for the clinical laboratory.

    Science.gov (United States)

    Place, J F; Truchaud, A; Ozawa, K; Pardue, H; Schnipelsky, P

    1995-01-01

    The incorporation of information-processing technology into analytical systems in the form of standard computing software has recently been advanced by the introduction of artificial intelligence (AI), both as expert systems and as neural networks.This paper considers the role of software in system operation, control and automation, and attempts to define intelligence. AI is characterized by its ability to deal with incomplete and imprecise information and to accumulate knowledge. Expert systems, building on standard computing techniques, depend heavily on the domain experts and knowledge engineers that have programmed them to represent the real world. Neural networks are intended to emulate the pattern-recognition and parallel processing capabilities of the human brain and are taught rather than programmed. The future may lie in a combination of the recognition ability of the neural network and the rationalization capability of the expert system.In the second part of the paper, examples are given of applications of AI in stand-alone systems for knowledge engineering and medical diagnosis and in embedded systems for failure detection, image analysis, user interfacing, natural language processing, robotics and machine learning, as related to clinical laboratories.It is concluded that AI constitutes a collective form of intellectual propery, and that there is a need for better documentation, evaluation and regulation of the systems already being used in clinical laboratories.

  3. Development of a Standardized Procedure for Cleaning Glass Apparatus in Analytical Laboratories

    Directory of Open Access Journals (Sweden)

    HUDSON C. POLONINI

    2011-06-01

    Full Text Available ABSTRACT Adequate cleaning of analytical glassware is an essential procedure that determines the reliability of assays and tests carried out in laboratories, keeping the glassware free of interference from residues left by previous tests. In the present paper, standard cleaning procedures are proposed for laboratory glassware, which were tested on cyanocobalamin as a marker contaminant. A spectrophotometric method was used for quantitative determination of both residual marker and cleaning product. Beakers, volumetric flasks and volumetric pipettes were successfully cleaned with a 2% detergent solution, with several rinses in water. Vials were cleaned adequately in an ultrasonic bath. These procedures utilize non-toxic and cheap reagents, factors of paramount importance for their application in routine laboratory analysis. Keywords: Validation Studies. Detergents. Laboratory Techniques and Procedures. Glassware Cleaning. RESUMO Desenvolvimento de procedimento padronizado para a lavagem de vidraria em laboratórios analíticos A lavagem da vidraria analítica é um procedimento essencial e determinante na confiabilidade dos resultados de testes e ensaios, a despeito da interferência dos resíduos de análises anteriores. Neste trabalho, foram propostos procedimentos de limpeza de vidrarias utilizando cianocobalamina como um marcador da eficiência de limpeza. Foi utilizado método espectrofotométrico para determinação dos resíduos do marcador e também do agente de limpeza. Béqueres, balões volumétricos e pipetas volumétricas foram comprovadamente limpos com detergente a 2% e múltiplos enxágues. Vials e seringas foram apropriadamente limpos utilizando-se banho ultrassônico. Esses procedimentos de limpeza fazem uso de reagentes baratos e não tóxicos, parâmetros de suma importância para sua aplicação em rotina laboratorial de análises físico-químicas. Palavras-chave: Estudos de Validação. Detergentes. Técnicas e

  4. Toward a quality guide to facilitate the transference of analytical methods from research to testing laboratories: a case study.

    Science.gov (United States)

    Bisetty, Krisnha; Gumede, Njabulo Joyfull; Escuder-Gilabert, Laura; Sagrado, Salvador

    2009-01-01

    At present, there is no single viewpoint that defines QA strategies in analytical chemistry. On the other hand, there are no unique protocols defining a set of analytical tasks and decision criteria to be performed during the method development phase (e.g., by a single research laboratory) in order to facilitate the transference to the testing laboratories intending to adapt, validate, and routinely use this method. This study proposes general criteria, a priori valid for any developed method, recommended as a provisional quality guide containing the minimum internal tasks necessary to publish new analytical method results. As an application, the selection of some basic internal quality tasks and the corresponding accepted criteria are adapted to a concrete case study: indirect differential pulse polarographic determination of nitrate in water samples according to European Commission requisites. Extra tasks to be performed by testing laboratories are also outlined.

  5. ASVCP quality assurance guidelines: control of preanalytical, analytical, and postanalytical factors for urinalysis, cytology, and clinical chemistry in veterinary laboratories.

    Science.gov (United States)

    Gunn-Christie, Rebekah G; Flatland, Bente; Friedrichs, Kristen R; Szladovits, Balazs; Harr, Kendal E; Ruotsalo, Kristiina; Knoll, Joyce S; Wamsley, Heather L; Freeman, Kathy P

    2012-03-01

    In December 2009, the American Society for Veterinary Clinical Pathology (ASVCP) Quality Assurance and Laboratory Standards committee published the updated and peer-reviewed ASVCP Quality Assurance Guidelines on the Society's website. These guidelines are intended for use by veterinary diagnostic laboratories and veterinary research laboratories that are not covered by the US Food and Drug Administration Good Laboratory Practice standards (Code of Federal Regulations Title 21, Chapter 58). The guidelines have been divided into 3 reports: (1) general analytical factors for veterinary laboratory performance and comparisons; (2) hematology, hemostasis, and crossmatching; and (3) clinical chemistry, cytology, and urinalysis. This particular report is one of 3 reports and documents recommendations for control of preanalytical, analytical, and postanalytical factors related to urinalysis, cytology, and clinical chemistry in veterinary laboratories and is adapted from sections 1.1 and 2.2 (clinical chemistry), 1.3 and 2.5 (urinalysis), 1.4 and 2.6 (cytology), and 3 (postanalytical factors important in veterinary clinical pathology) of these guidelines. These guidelines are not intended to be all-inclusive; rather, they provide minimal guidelines for quality assurance and quality control for veterinary laboratory testing and a basis for laboratories to assess their current practices, determine areas for improvement, and guide continuing professional development and education efforts.

  6. Fitting It All In: Adapting a Green Chemistry Extraction Experiment for Inclusion in an Undergraduate Analytical Laboratory

    Science.gov (United States)

    Buckley, Heather L.; Beck, Annelise R.; Mulvihill, Martin J.; Douskey, Michelle C.

    2013-01-01

    Several principles of green chemistry are introduced through this experiment designed for use in the undergraduate analytical chemistry laboratory. An established experiment of liquid CO2 extraction of D-limonene has been adapted to include a quantitative analysis by gas chromatography. This facilitates drop-in incorporation of an exciting…

  7. 40 CFR Appendix G to Subpart A of... - UNEP Recommendations for Conditions Applied to Exemption for Essential Laboratory and Analytical...

    Science.gov (United States)

    2010-07-01

    ... Applied to Exemption for Essential Laboratory and Analytical Uses G Appendix G to Subpart A of Part 82... STRATOSPHERIC OZONE Production and Consumption Controls Pt. 82, Subpt. A, App. G Appendix G to Subpart A of Part.... The provisions of Appendix G, paragraphs (1), (2), (3), and (4), regarding purity, mixing,...

  8. Comparison between Laboratory Measurements, Simulations and Analytical Predictions of the Resistive Wall Transverse Beam Impedance at low frequencies

    CERN Document Server

    Roncarolo, F; Kroyer, T; Métral, E; Salvant, B

    2008-01-01

    The prediction of the resistive wall transverse beam impedance at the first unstable betatron line (8 kHz) of the CERN Large Hadron Collider (LHC) is of paramount importance for understanding and controlling the related coupled-bunch instability. Until now only novel analytical formulas were available at this frequency. Recently, laboratory measurements and numerical simulations were performed to crosscheck the analytical predictions. The experimental results based on the measurement of the variation of a probe coil inductance in the presence of i) sample graphite plates, ii) stand-alone LHC collimator jaws and iii) a full LHC collimator assembly are presented in detail. The measurement results are compared to both analytical theories and simulations. In addition, the consequences for the understanding of the LHC impedance are discussed.

  9. [The analytical reliability of clinical laboratory information and role of the standards in its support].

    Science.gov (United States)

    Men'shikov, V V

    2012-12-01

    The article deals with the factors impacting the reliability of clinical laboratory information. The differences of qualities of laboratory analysis tools produced by various manufacturers are discussed. These characteristics are the causes of discrepancy of the results of laboratory analyses of the same analite. The role of the reference system in supporting the comparability of laboratory analysis results is demonstrated. The project of national standard is presented to regulate the requirements to standards and calibrators for analysis of qualitative and non-metrical characteristics of components of biomaterials.

  10. Juicing the Juice: A Laboratory-Based Case Study for an Instrumental Analytical Chemistry Course

    Science.gov (United States)

    Schaber, Peter M.; Dinan, Frank J.; St. Phillips, Michael; Larson, Renee; Pines, Harvey A.; Larkin, Judith E.

    2011-01-01

    A young, inexperienced Food and Drug Administration (FDA) chemist is asked to distinguish between authentic fresh orange juice and suspected reconstituted orange juice falsely labeled as fresh. In an advanced instrumental analytical chemistry application of this case, inductively coupled plasma (ICP) spectroscopy is used to distinguish between the…

  11. International Federation of Clinical Chemistry. Use of artificial intelligence in analytical systems for the clinical laboratory. IFCC Committee on Analytical Systems.

    Science.gov (United States)

    Place, J F; Truchaud, A; Ozawa, K; Pardue, H; Schnipelsky, P

    1994-12-16

    The incorporation of information-processing technology into analytical systems in the form of standard computing software has recently been advanced by the introduction of artificial intelligence (AI) both as expert systems and as neural networks. This paper considers the role of software in system operation, control and automation and attempts to define intelligence. AI is characterized by its ability to deal with incomplete and imprecise information and to accumulate knowledge. Expert systems, building on standard computing techniques, depend heavily on the domain experts and knowledge engineers that have programmed them to represent the real world. Neural networks are intended to emulate the pattern-recognition and parallel-processing capabilities of the human brain and are taught rather than programmed. The future may lie in a combination of the recognition ability of the neural network and the rationalization capability of the expert system. In the second part of this paper, examples are given of applications of AI in stand-alone systems for knowledge engineering and medical diagnosis and in embedded systems for failure detection, image analysis, user interfacing, natural language processing, robotics and machine learning, as related to clinical laboratories. It is concluded that AI constitutes a collective form of intellectual property and that there is a need for better documentation, evaluation and regulation of the systems already being used widely in clinical laboratories.

  12. Analytical Strategies for Drug Residues in Various Matrices in a Regulatory Laboratory.

    OpenAIRE

    Dowling, Geraldine

    2012-01-01

    Abstract Today, in modern farming practices veterinary drugs are given to food-producing animals. The generic term “veterinary drugs” covers a broad variety of classes of chemical compounds and the list of drugs is enormous and it is a significant analytical challenge in regulatory control to provide monitoring programmes. The major concerns in veterinary drug usage are the presence of harmful residues that may be introduced into the human food chain. The aim of this research is the develo...

  13. Incorporating Course-Based Undergraduate Research Experiences into Analytical Chemistry Laboratory Curricula

    Science.gov (United States)

    Kerr, Melissa A.; Yan, Fei

    2016-01-01

    A continuous effort within an undergraduate university setting is to improve students' learning outcomes and thus improve students' attitudes about a particular field of study. This is undoubtedly relevant within a chemistry laboratory. This paper reports the results of an effort to introduce a problem-based learning strategy into the analytical…

  14. 76 FR 41747 - Protection of Stratospheric Ozone: Extension of Global Laboratory and Analytical Use Exemption...

    Science.gov (United States)

    2011-07-15

    ... (Art. 2B), carbon tetrachloride (Art. 2D), methyl chloroform (Art. 2E), hydrobromofluorocarbons (Art... (polydimethylsiloxane) (iii) when recording infrared and nuclear magnetic resonance (NMR) spectra, including hydroxyl... as laboratory solvent, namely (i) washing of NMR tubes (ii) removal of greases from glassware EPA...

  15. Clinical evaluation of analytical variations in serum creatinine measurements: why laboratories should abandon Jaffe techniques

    Directory of Open Access Journals (Sweden)

    Drion Iefke

    2012-10-01

    Full Text Available Abstract Background Non-equivalence in serum creatinine (SCr measurements across Dutch laboratories and the consequences hereof on chronic kidney disease (CKD staging were examined. Methods National data from the Dutch annual external quality organization of 2009 were used. 144 participating laboratories examined 11 pairs of commutable, value-assigned SCr specimens in the range 52–262 μmol/L, using Jaffe or enzymatic techniques. Regression equations were created for each participating laboratory (by regressing values as measured by participating laboratories on the target values of the samples sent by the external quality organization; area under the curves were examined and used to rank laboratories. The 10th and 90th percentile regression equation were selected for each technique separately. To evaluate the impact of the variability in SCr measurements and its eventual clinical consequences in a real patient population, we used a cohort of 82424 patients aged 19–106 years. The SCr measurements of these 82424 patients were introduced in the 10th and 90th percentile regression equations. The newly calculated SCr values were used to calculate an estimated glomerular filtration rate (eGFR using the 4-variable Isotope Dilution Mass Spectrometry traceable Modification of Diet in Renal Disease formula. Differences in CKD staging were examined, comparing the stratification outcomes for Jaffe and enzymatic SCr techniques. Results Jaffe techniques overestimated SCr: 21%, 12%, 10% for SCr target values 52, 73 and 94 μmol/L, respectively. For enzymatic assay these values were 0%, -1%, -2%, respectively. eGFR using the MDRD formula and SCr measured by Jaffe techniques, staged patients in a lower CKD category. Downgrading to a lower CKD stage occurred in 1-42%, 2-37% and 12–78.9% of patients for the 10th and 90th percentile laboratories respectively in CKD categories 45–60, 60–90 and >90 ml/min/1.73 m2. Using enzymatic techniques, downgrading

  16. Analytical performance specifications: relating laboratory performance to quality required for intended clinical use.

    Science.gov (United States)

    Dalenberg, Daniel A; Schryver, Patricia G; Klee, George G

    2013-03-01

    This article proposes analytic performance goals for five quality indicators: precision, trueness, linearity, detection limits, and consistency across instruments and time. We defined our goals using methods linked to clinical practice data. Goals for desirable precision and trueness are based on biological variation. Linearity goals are related to total error recommendations. Detection limit goals are derived from 0.1 percentile of patient values. Goals for consistency are derived from the variability of distributions of patient test values. Data were collected and evaluated for each of these quality indicators for 46 chemistry tests measured on the Roche cobas 8000 analyzer.

  17. Emotions beyond the laboratory: theoretical fundaments, study design, and analytic strategies for advanced ambulatory assessment.

    Science.gov (United States)

    Wilhelm, Frank H; Grossman, Paul

    2010-07-01

    Questionnaire and interview assessment can provide reliable data on attitudes and self-perceptions on emotion, and experimental laboratory assessment can examine functional relations between stimuli and reactions under controlled conditions. On the other hand, ambulatory assessment is less constrained and provides naturalistic data on emotion in daily life, with the potential to (1) assure external validity of laboratory findings, (2) provide normative data on prevalence, quality and intensity of real-life emotion and associated processes, (3) characterize previously unidentified emotional phenomena, and (4) model real-life stimuli for representative laboratory research design. Technological innovations now allow for detailed ambulatory study of emotion across domains of subjective experience, overt behavior and physiology. However, methodological challenges abound that may compromise attempts to characterize biobehavioral aspects of emotion in the real world. For example, emotional effects can be masked by social engagement, mental and physical workloads, as well as by food intake and circadian and quasi-random variation in metabolic activity. The complexity of data streams and multitude of factors that influence them require a high degree of context specification for meaningful data interpretation. We consider possible solutions to typical and often overlooked issues related to ambulatory emotion research, including aspects of study design decisions, recording devices and channels, electronic diary implementation, and data analysis.

  18. The Efficacy of Problem-based Learning in an Analytical Laboratory Course for Pre-service Chemistry Teachers

    Science.gov (United States)

    Yoon, Heojeong; Woo, Ae Ja; Treagust, David; Chandrasegaran, AL

    2014-01-01

    The efficacy of problem-based learning (PBL) in an analytical chemistry laboratory course was studied using a programme that was designed and implemented with 20 students in a treatment group over 10 weeks. Data from 26 students in a traditional analytical chemistry laboratory course were used for comparison. Differences in the creative thinking ability of students in both the treatment and control groups were evaluated before and at the end of the implementation of the programme, using the Torrance Tests of Creative Thinking. In addition, changes in students' self-regulated learning skills using the Self-Regulated Learning Interview Schedule (SRLIS) and their self-evaluation proficiency were evaluated. Analysis of covariance showed that the creative thinking ability of the treatment group had improved statistically significantly after the PBL course (p self-regulated learning strategies more frequently than students in the comparison group. According to the results of the self-evaluation, students became more positive and confident in problem-solving and group work as the semester progressed. Overall, PBL was shown to be an effective pedagogical instructional strategy for enhancing chemistry students' creative thinking ability, self-regulated learning skills and self-evaluation.

  19. Towards a green analytical laboratory: microextraction techniques as a useful tool for the monitoring of polluted soils

    Science.gov (United States)

    Lopez-Garcia, Ignacio; Viñas, Pilar; Campillo, Natalia; Hernandez Cordoba, Manuel; Perez Sirvent, Carmen

    2016-04-01

    Microextraction techniques are a valuable tool at the analytical laboratory since they allow sensitive measurements of pollutants to be carried out by means of easily available instrumentation. There is a large number of such procedures involving miniaturized liquid-liquid or liquid-solid extractions with the common denominator of using very low amounts (only a few microliters) or even none of organic solvents. Since minimal amounts of reagents are involved, and the generation of residues is consequently minimized, the approach falls within the concept of Green Analytical Chemistry. This general methodology is useful both for inorganic and organic pollutants. Thus, low amounts of metallic ions can be measured without the need of using ICP-MS since this instrument can be replaced by a simple AAS spectrometer which is commonly present in any laboratory and involves low acquisition and maintenance costs. When dealing with organic pollutants, the microextracts obtained can be introduced into liquid or gas chromatographs equipped with common detectors and there is no need for the most sophisticated and expensive mass spectrometers. This communication reports an overview of the advantages of such a methodology, and gives examples for the determination of some particular contaminants in soil and water samples The authors are grateful to the Comunidad Autonóma de la Región de Murcia , Spain (Fundación Séneca, 19888/GERM/15) for financial support

  20. Analytical Plans Supporting The Sludge Batch 8 Glass Variability Study Being Conducted By Energysolutions And Cua's Vitreous State Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, T. B.; Peeler, D. K.

    2012-11-26

    EnergySolutions (ES) and its partner, the Vitreous State Laboratory (VSL) of The Catholic University of America (CUA), are to provide engineering and technical services support to Savannah River Remediation, LLC (SRR) for ongoing operation of the Defense Waste Processing Facility (DWPF) flowsheet as well as for modifications to improve overall plant performance. SRR has requested via a statement of work that ES/VSL conduct a glass variability study (VS) for Sludge Batch 8. SRR issued a technical task request (TTR) asking that the Savannah River National Laboratory (SRNL) provide planning and data reduction support for the ES/VSL effort. This document provides two analytical plans for use by ES/VSL: one plan is to guide the measurement of the chemical composition of the study glasses while the second is to guide the measurement of the durability of the study glasses. The measurements generated by ES/VSL are to be provided to SRNL for data reduction and evaluation. SRNL is to review the results of its evaluation with ES/VSL and SRR. The results will subsequently be incorporated into a joint report with ES/VSL as a deliverable to SRR to support the processing of SB8 at DWPF.

  1. ANALYTICAL PLANS SUPPORTING THE SWPF GAP ANALYSIS BEING CONDUCTED WITH ENERGYSOLUTIONS AND THE VITREOUS STATE LABORATORY AT THE CUA

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, T.; Peeler, D.

    2014-10-28

    EnergySolutions (ES) and its partner, the Vitreous State Laboratory (VSL) of The Catholic University of America (CUA), are to provide engineering and technical services support to Savannah River Remediation, LLC (SRR) for ongoing operation of the Defense Waste Processing Facility (DWPF) flowsheet as well as for modifications to improve overall plant performance. SRR has requested that the glass formulation team of Savannah River National Laboratory (SRNL) and ES-VSL develop a technical basis that validates the current Product Composition Control System models for use during the processing of the coupled flowsheet or that leads to the refinements of or modifications to the models that are needed so that they may be used during the processing of the coupled flowsheet. SRNL has developed a matrix of test glasses that are to be batched and fabricated by ES-VSL as part of this effort. This document provides two analytical plans for use by ES-VSL: one plan is to guide the measurement of the chemical composition of the study glasses while the second is to guide the measurement of the durability of the study glasses based upon the results of testing by ASTM’s Product Consistency Test (PCT) Method A.

  2. Determination of Total Arsenic and Speciation in Apple Juice by Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry: An Experiment for the Analytical Chemistry Laboratory

    Science.gov (United States)

    He, Ping; Colon, Luis A.; Aga, Diana S.

    2016-01-01

    A two-part laboratory experiment was designed for upper-level analytical chemistry students to provide hands-on experience in the use of high performance liquid chromatography (HPLC) for separation and inductively coupled plasma mass spectrometry (ICP-MS) for detection. In the first part of the experiment, the students analyze total arsenic in…

  3. Developing and Implementing Inquiry-Based, Water Quality Laboratory Experiments for High School Students to Explore Real Environmental Issues Using Analytical Chemistry

    Science.gov (United States)

    Mandler, Daphna; Blonder, Ron; Yayon, Malka; Mamlok-Naaman, Rachel; Hofstein, Avi

    2014-01-01

    This paper describes the rationale and the implementation of five laboratory experiments; four of them, intended for high-school students, are inquiry-based activities that explore the quality of water. The context of water provides students with an opportunity to study the importance of analytical methods and how they influence our everyday…

  4. Statistical comparison of the results from six analytical chemistry laboratories of the mercury content of muscle tissue of two species of sharks.

    Science.gov (United States)

    Walker, T I

    1977-01-01

    Statistical tests were carried out on the results of chemical analysis for total mercury concentrations of replicate samples of muscle tissue of school shark Galeorhinus australis (Macleay) and gummy shark Mustelus antarcticus Guenther from six independent analytical laboratories. These tests showed that one laboratory produced results 9% below the overall average of all results, another 1% below average while the other four were all 5% above average. Moreover, one laboratory had significantly lower scatter of results than the others, and the percentage scatter (standard error expressed as a percentage of the mean) in two of the laboratories tended to diminish as the magnitude of the results increased. Correction for what were concluded to be wild points indicated that the scatter for all laboratories was below 14%.

  5. Statistical comparison of the results from six analytical chemistry laboratories of the mercury content of muscle tissue of two species of sharks

    Energy Technology Data Exchange (ETDEWEB)

    Walker, T.I.

    1977-01-01

    Statistical tests were carried out on the results of chemical analysis for total mercury concentrations of replicate samples of muscle tissue of school shark Galeorhinus australis (Macleay) and gummy shark Mustelus antarcticus Guenther from six independent analytical laboratories. These tests showed that one laboratory produced results 9% below the overall average of all results, another 1% below average while the other four were all 5% above average. Moreover, one laboratory had significantly lower scatter of results than the others, and the percentage scatter (standard error expressed as a percentage of the mean) in two of the laboratories tended to diminish as the magnitude of the results increased. Correction for what were concluded to be wild points indicated that the scatter for all laboratories was below 14%.

  6. Analysis of Environmental Contamination resulting from Catastrophic Incidents: Part two: Building Laboratory Capability by Selecting and Developing Analytical Methodologies

    Science.gov (United States)

    Catastrophic incidents can generate a large number of samples with analytically diverse types including forensic, clinical, environmental, food, and others. Environmental samples include water, wastewater, soil, air, urban building and infrastructure materials, and surface resid...

  7. Authentic Learning Enviroment in Analytical Chemistry Using Cooperative Methods and Open-Ended Laboratories in Large Lecture Courses

    Science.gov (United States)

    Wright, John C.

    1996-09-01

    It is recognized that a need exists to move from the passive learning styles that have characterized chemistry courses to an active style in which students participate and assume responsibility for their learning (1 - 5). In addition, it is argued that course reform should be linked to authentic student achievement, so that students can actively experience the feelings of practicing professionals (6). Course experiments where such changes have been introduced have proven successful but the number of examples of such changes is limited in the higher level courses or courses with large enrollments (7 - 11). In this paper, a one-semester introductory analytical chemistry course is described that accomplishes this goal by the use of open-ended laboratories, cooperative learning, and spreadsheet programs. The course uses many of the ideas described by Walters (7). It is offered at the upperclass level to nonmajors and at the freshman level to students with solid chemistry backgrounds from high school. Typically there are 90 students, who are divided into 5 sections. A teaching assistant is assigned to each section. The course has two 4-hour laboratories and two or three lectures each week (depending on whether it is the upperclass or freshman course). The heart of the course changes is the use of open-ended laboratory experiments in the last half of the course. A sample group project is to have the students develop a mixture of acid-base indicators that can serve as a spectroscopic pH meter. These projects are enhanced by dividing the students into teams of four who take charge of all aspects of accomplishing the projects' goals. Since there are many skills required to make these projects work, the first half of the course is spent developing the individual conceptual, computational, laboratory, problem solving, and group skills so students are prepared for the last half. These changes have markedly improved the student attitudes towards each other and towards learning

  8. FastTrack to supercritical fluid chromatographic purification: Implementation of a walk-up analytical supercritical fluid chromatography/mass spectrometry screening system in the medicinal chemistry laboratory.

    Science.gov (United States)

    Aurigemma, Christine; Farrell, William

    2010-09-24

    Medicinal chemists often depend on analytical instrumentation for reaction monitoring and product confirmation at all stages of pharmaceutical discovery and development. To obtain pure compounds for biological assays, the removal of side products and final compounds through purification is often necessary. Prior to purification, chemists often utilize open-access analytical LC/MS instruments because mass confirmation is fast and reliable, and the chromatographic separation of most sample constituents is sufficient. Supercritical fluid chromatography (SFC) is often used as an orthogonal technique to HPLC or when isolation of the free base of a compound is desired. In laboratories where SFC is the predominant technique for analysis and purification of compounds, a reasonable approach for quickly determining suitable purification conditions is to screen the sample against different columns. This can be a bottleneck to the purification process. To commission SFC for open-access use, a walk-up analytical SFC/MS screening system was implemented in the medicinal chemistry laboratory. Each sample is automatically screened through six column/method conditions, and on-demand data processing occurs for the chromatographers after each screening method is complete. This paper highlights the "FastTrack" approach to expediting samples through purification.

  9. Quality control for the in-clinic veterinary laboratory and pre-analytic considerations for specialized diagnostic testing.

    Science.gov (United States)

    Camus, Melinda S

    2016-09-01

    This review, aimed primarily at general practitioners, focuses on quality assurance/quality control principles for all three phases of clinical pathology testing: preanalytic, analytic, and postanalytic. Specific emphasis is placed on the preanalytic phase of diagnostic modalities for identifying neoplastic cells, specifically flow cytometry, PCR for antigen receptor rearrangement, and immunocytochemistry. Recommendations for establishing an in-clinic quality assurance system are provided.

  10. Analytical Scanning and Transmission Electron Microscopy of Laboratory Impacts on Stardust Aluminium Foils: Interpreting Impact Crater Morphology and the Composition of Impact Residues.

    Energy Technology Data Exchange (ETDEWEB)

    Kearsley, A T; Graham, G A; Burchell, M J; Cole, M J; Dai, Z R; Teslich, N; Chater, R; Wozniakiewicz, P A; Spratt, J; Jones, G

    2006-10-19

    The known encounter velocity (6.1kms{sup -1}) between the Stardust spacecraft and the dust emanating from the nucleus of comet Wild 2 has allowed realistic simulation of dust collection in laboratory experiments designed to validate analytical methods for the interpretation of dust impacts on the aluminium foil components of the Stardust collector. In this report we present information on crater gross morphology, the pre-existing major and trace element composition of the foil, geometrical issues for energy dispersive X-ray analysis of the impact residues in scanning electron microscopes, and the modification of dust chemical composition during creation of impact craters as revealed by analytical transmission electron microscopy. Together, these observations help to underpin the interpretation of size, density and composition for particles impacted upon the Stardust aluminium foils.

  11. Assembly of a Modular Fluorimeter and Associated Software: Using LabVIEW in an Advanced Undergraduate Analytical Chemistry Laboratory

    Science.gov (United States)

    Algar, W. Russ; Massey, Melissa; Krull, Ulrich J.

    2009-01-01

    A laboratory activity for an upper-level undergraduate course in instrumental analysis has been created around LabVIEW. Students learn rudimentary programming and interfacing skills during the construction of a fluorimeter assembled from common modular components. The fluorimeter consists of an inexpensive data acquisition module, LED light…

  12. GLYCOHEMOGLOBIN - COMPARISON OF 12 ANALYTICAL METHODS, APPLIED TO LYOPHILIZED HEMOLYSATES BY 101 LABORATORIES IN AN EXTERNAL QUALITY ASSURANCE PROGRAM

    NARCIS (Netherlands)

    WEYKAMP, CW; PENDERS, TJ; MUSKIET, FAJ; VANDERSLIK, W

    1993-01-01

    Stable lyophilized ethylenediaminetetra-acetic acid (EDTA)-blood haemolysates were applied in an external quality assurance programme (SKZL, The Netherlands) for glycohaemoglobin assays in 101 laboratories using 12 methods. The mean intralaboratory day-to-day coefficient of variation (CV), calculate

  13. An Internet-based external quality assessment in cytogenetics that audits a laboratory's analytical and interpretative performance.

    Science.gov (United States)

    Hastings, Rosalind J; Maher, Eddy J; Quellhorst-Pawley, Bettina; Howell, Rodney T

    2008-10-01

    A novel approach to external quality assessment (EQA) using the Internet mimics the diagnostic situation so that multiple tests can be requested and EQA cases can be 'tailor made' to address a specific chromosome syndrome, disease, or clinical dilemma. The web-based EQA system was trialled on a large UK EQA scheme, UK NEQAS for Clinical Cytogenetics. It has also been used to implement a new Cytogenetics European Quality Assessment scheme, CEQA, set up with the intention of providing laboratories in countries without access to a local EQA scheme the opportunity of participation in EQA. Overall, Internet-based EQA allows for a varied EQA programme. Poor performance was detected in both CEQA and UK NEQAS constitutional EQA schemes and also in the UK NEQAS oncology EQA scheme. The Internet-based EQA overcomes submission delays due to international surface mail. There is also a reduction in administration and assessors' time compared to a retrospective EQA involving the submission of unique cases for EQA assessment, as participants analyse the same three Internet-based EQA cases simultaneously. Many EU27 (EU member states) laboratories still do not participate in their national EQA schemes, so until EQA participation becomes mandatory as a component of compulsory laboratory accreditation, the quality of laboratory diagnostic service is unpredictable.

  14. Gold Electrodes Modified with Self-Assembled Monolayers for Measuring L-Ascorbic Acid: An Undergraduate Analytical Chemistry Laboratory Experiment

    Science.gov (United States)

    Ito, Takashi; Perera, D. M. Neluni T.; Nagasaka, Shinobu

    2008-01-01

    This article describes an undergraduate electrochemistry laboratory experiment in which the students measure the L-ascorbic acid content of a real sample. Gold electrodes modified with self-assembled monolayers (SAMs) of thioctic acid and cysteamine are prepared to study the effects of surface modification on the electrode reaction of L-ascorbic…

  15. Laboratory-scale evaluation of various sampling and analytical methods for determining mercury emissions from coal-fired power plants

    Energy Technology Data Exchange (ETDEWEB)

    Agbede, R.O.; Bochan, A.J.; Clements, J.L. [Advanced Technology Systems, Inc., Monroeville, PA (United States)] [and others

    1995-11-01

    Comparative bench-scale mercury sampling method tests were performed at the Advanced Technology Systems, Inc. (ATS) laboratories for EPA Method 101A, EPA Method 29 and the Ontario Hydro Method. Both blank and impinger spiking experiments were performed. The experimental results show that the ambient level of mercury in the ATS laboratory is at or below the detection limit (10 ng Hg) as measured by a cold vapor atomic absorption spectrophotometer (CVAAS) which was used to analyze the mercury samples. From the mercury spike studies, the following observations and findings were made. (a) The recovery of mercury spikes using EPA Method 101A was 104%. (b) The Ontario Hydro Method retains about 90% of mercury spikes in the first absorbing solution but has a total spike retention of 106%. As a result, the test data shows possible migration of spiked mercury from the first impinger solution (KCI) to the permanganate impingers. (c) For the EPA Method 29 solutions, when only the peroxide impingers were spiked, mercury recoveries were 65.6% for the peroxide impingers, 0.1% for the knockout impinger and 32.8% for the permanganate impingers with an average total mercury recovery of 98.4%. At press time, data was still being obtained for both the peroxide and permanganate impinger solution spikes. This and other data will be available at the presentation.

  16. Analysis of Reference Cigarette Smoke Yield Data From 21 Laboratories for 28 Selected Analytes as a Guide to Selection of New Coresta Recommended Methods

    Directory of Open Access Journals (Sweden)

    Purkis Steve

    2014-07-01

    Full Text Available Since 1999, the CORESTA Special Analytes Sub Group (SPA SG has been working on the development of CORESTA Recommended Methods (CRMs for the analysis of cigarette smoke components. All CRMs have been posted on the CORESTA website and several associated papers published. In this study, 21 laboratories shared data and in-house methodologies for 28 additional smoke components of regulatory interest to prioritise the development of further CRMs. Laboratories provided data, where available, from CORESTA monitor test pieces (CM6 and CM7 and Kentucky Reference Cigarettes (1R5F / 3R4F covering the period 2010-2012 obtained under both the ISO 3308 and Health Canada Intense regimes. Scant data were available on the CORESTA monitor test pieces and the Kentucky 1R5F reference. The greatest amount of data was obtained on the Kentucky 3R4F and this was used in the analyses described in this paper. SPA SG discussions provided invaluable insight into identifying causes and ways of reducing inter-laboratory variability which will be investigated in joint experiments before embarking on final collaborative studies using draft CRMs to obtain mean yields, repeatability and reproducibility values. Phenolic compounds (phenol, 3 cresol isomers, hydroquinone, catechol and resorcinol gave consistent results by liquid chromatography (LC separation and fluorescence detection after extracting collected “tar” on a Cambridge filter pad (CFP. Yields were similar to those obtained by a derivatisation method followed by gas chromatography - mass spectrometry (GC-MS analysis. Similar ratios of phenols were also obtained from each method. Of the 28 studied analytes, the between-laboratory variability was lowest for the phenols. Hydrogen cyanide was derivatised using various reagents and the colour development measured after continuous flow analysis (CFA by ultra-violet absorbance. Although, methodologies gave reasonably consistent results, investigations on the trapping system

  17. Analytical Electron Microscope

    Data.gov (United States)

    Federal Laboratory Consortium — The Titan 80-300 is a transmission electron microscope (TEM) equipped with spectroscopic detectors to allow chemical, elemental, and other analytical measurements to...

  18. Wind Structural Testing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This facility provides office space for industry researchers, experimental laboratories, computer facilities for analytical work, and space for assembling components...

  19. Analytical scanning and transmission electron microscopy of laboratory impacts on Stardust aluminum foils: interpreting impact crater morphology and the composition of impact residues

    CERN Document Server

    Kearsley, A T; Burchell, M J; Cole, M J; Dai, Z R; Teslich, N; Bradley, J P; Chater, R; Wozniakiewicz, P A; Spratt, J; Jones, G

    2006-01-01

    The known encounter velocity (6.1kms-1) and particle incidence angle (perpendicular) between the Stardust spacecraft and the dust emanating from the nucleus of comet Wild 2 fall within a range that allows simulation in laboratory light gas gun experiments designed to validate analytical methods for the interpretation of dust impacts on the aluminum foil components of the Stardust collector. Buckshot of a wide size, shape and density range of mineral, glass, polymer and metal grains, have been fired to impact perpendicularly upon samples of Stardust Al1100 foil, tightly wrapped onto aluminium alloy plate as an analogue of foil on the spacecraft collector. We have not yet been able to produce laboratory impacts by projectiles with weak and porous aggregate structure, as may occur in some cometary dust grains. In this report we present information on crater gross morphology and its dependence on particle size and density, the pre-existing major and trace element composition of the foil, geometrical issues for en...

  20. Product and market study for Los Alamos National Laboratory. Building resources for technology commercialization: The SciBus Analytical, Inc. paradigm

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The study project was undertaken to investigate how entrepreneurial small businesses with technology licenses can develop product and market strategies sufficiently persuasive to attract resources and exploit commercialization opportunities. The study attempts to answer two primary questions: (1) What key business development strategies are likely to make technology transfers successful, and (2) How should the plan best be presented in order to attract resources (e.g., personnel, funding, channels of distribution)? In the opinion of the investigator, Calidex Corporation, if the business strategies later prove to be successful, then the plan model has relevance for any technology licensee attempting to accumulate resources and bridge from technology resident in government laboratories to the commercial marketplace. The study utilized SciBus Analytical, Inc. (SciBus), a Los Alamos National Laboratory CRADA participant, as the paradigm small business technology licensee. The investigator concluded that the optimum value of the study lay in the preparation of an actual business development plan for SciBus that might then have, hopefully, broader relevance and merit for other private sector technology transfer licensees working with various Government agencies.

  1. Dual-domain mass-transfer parameters from electrical hysteresis: theory and analytical approach applied to laboratory, synthetic streambed, and groundwater experiments

    Science.gov (United States)

    Briggs, Martin; Day-Lewis, Frederick D.; Ong, John B.; Harvey, Judson W.; Lane, Jr., John W.

    2014-01-01

    Models of dual-domain mass transfer (DDMT) are used to explain anomalous aquifer transport behavior such as the slow release of contamination and solute tracer tailing. Traditional tracer experiments to characterize DDMT are performed at the flow path scale (meters), which inherently incorporates heterogeneous exchange processes; hence, estimated “effective” parameters are sensitive to experimental design (i.e., duration and injection velocity). Recently, electrical geophysical methods have been used to aid in the inference of DDMT parameters because, unlike traditional fluid sampling, electrical methods can directly sense less-mobile solute dynamics and can target specific points along subsurface flow paths. Here we propose an analytical framework for graphical parameter inference based on a simple petrophysical model explaining the hysteretic relation between measurements of bulk and fluid conductivity arising in the presence of DDMT at the local scale. Analysis is graphical and involves visual inspection of hysteresis patterns to (1) determine the size of paired mobile and less-mobile porosities and (2) identify the exchange rate coefficient through simple curve fitting. We demonstrate the approach using laboratory column experimental data, synthetic streambed experimental data, and field tracer-test data. Results from the analytical approach compare favorably with results from calibration of numerical models and also independent measurements of mobile and less-mobile porosity. We show that localized electrical hysteresis patterns resulting from diffusive exchange are independent of injection velocity, indicating that repeatable parameters can be extracted under varied experimental designs, and these parameters represent the true intrinsic properties of specific volumes of porous media of aquifers and hyporheic zones.

  2. European multicentre evaluation of the Du Pont Dimension 380 under the auspices of the European Group for the Evaluation of Analytical Systems in Laboratory Medicine (EGE-Lab).

    Science.gov (United States)

    Hänseler, E; Vonderschmitt, D; Haeckel, R; Römer, M; Collombel, C; Goudable, J; Pourcher, E

    1991-01-01

    The Clinical Chemistry Analyzer Dimension 380 manufactured by Du Pont de Nemours was tested in a multicentre evaluation according to the guide-lines of the European Committee for Clinical Laboratory Standards (ECCLS) and in part to the protocol of the Société Française de Biologie Clinique (SFBC). The instrument and the reagents were evaluated as a system, since both reagents and reagent cartridges are specifically designed for the instrument. Fourteen analytes including electrolytes, substrates and enzymes were tested. The evaluators summarized their experience as follows: 1. All parameters tested yield results comparable to established procedures. 2. Very good performance of the ion-selective-electrode unit. 3. The imprecision data of the system are, for most parameters, between 1 and 4% CV and thus equal to or better than those of the instruments compared. 4. No reagent or sample carry-over was detected after a minor modification of the instrument. 5. The linearity of Dimension test methods in general covers the range stated by the manufacturer. 6. Very good stability of the calibration curves (up to 2 months). 7. Good practicability of the whole system, including handling of reagents and a very user-friendly software.

  3. Denver District Laboratory (DEN)

    Data.gov (United States)

    Federal Laboratory Consortium — Program CapabilitiesDEN-DO Laboratory is a multi-functional laboratory capable of analyzing most chemical analytes and pathogenic/non-pathogenic microorganisms found...

  4. 统计质量保证技术在分析测试实验室内部质量控制中的应用%Application of SQA Techniques to Analytical and Testing Laboratories for Internal Quality Control

    Institute of Scientific and Technical Information of China (English)

    王斗文; 万秉忠

    2001-01-01

    对通过统计质量保证( SQA)技术进行分析测试实验室内部质量控制( IQC)的方法作了初探。研究结果表明,SQA技术的应用能保证实验室始终处于统计受控状态,确保测试数据的有效性,有利于分析测试实验室质量保证活动的开展。%In this paper,a method of internal quality control for analytical and testing laboratories by statistical quality assurance(SQA) techniques is discussed.Application of SQA techniques can be continuously ensure that analytical and testing data of the laboratories are in statistical _ control state,thus guaranteeing the data quality and indicating areas of potential improvement for the laboratories.

  5. Analytical mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    This 43rd Annual Summer Symposium on Analytical Chemistry was held July 24--27, 1990 at Oak Ridge, TN and contained sessions on the following topics: Fundamentals of Analytical Mass Spectrometry (MS), MS in the National Laboratories, Lasers and Fourier Transform Methods, Future of MS, New Ionization and LC/MS Methods, and an extra session. (WET)

  6. Analytical mass spectrometry. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-31

    This 43rd Annual Summer Symposium on Analytical Chemistry was held July 24--27, 1990 at Oak Ridge, TN and contained sessions on the following topics: Fundamentals of Analytical Mass Spectrometry (MS), MS in the National Laboratories, Lasers and Fourier Transform Methods, Future of MS, New Ionization and LC/MS Methods, and an extra session. (WET)

  7. Virtual Reality Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Performs basic and applied research in interactive 3D computer graphics, including visual analytics, virtual environments, and augmented reality (AR). The...

  8. Low-Cost Method for Quantifying Sodium in Coconut Water and Seawater for the Undergraduate Analytical Chemistry Laboratory: Flame Test, a Mobile Phone Camera, and Image Processing

    Science.gov (United States)

    Moraes, Edgar P.; da Silva, Nilbert S. A.; de Morais, Camilo de L. M.; das Neves, Luiz S.; de Lima, Kassio M. G.

    2014-01-01

    The flame test is a classical analytical method that is often used to teach students how to identify specific metals. However, some universities in developing countries have difficulties acquiring the sophisticated instrumentation needed to demonstrate how to identify and quantify metals. In this context, a method was developed based on the flame…

  9. Estimating the Analytical and Surface Enhancement Factors in Surface-Enhanced Raman Scattering (SERS): A Novel Physical Chemistry and Nanotechnology Laboratory Experiment

    Science.gov (United States)

    Pavel, Ioana E.; Alnajjar, Khadijeh S.; Monahan, Jennifer L.; Stahler, Adam; Hunter, Nora E.; Weaver, Kent M.; Baker, Joshua D.; Meyerhoefer, Allie J.; Dolson, David A.

    2012-01-01

    A novel laboratory experiment was successfully implemented for undergraduate and graduate students in physical chemistry and nanotechnology. The main goal of the experiment was to rigorously determine the surface-enhanced Raman scattering (SERS)-based sensing capabilities of colloidal silver nanoparticles (AgNPs). These were quantified by…

  10. Using Modern Solid-State Analytical Tools for Investigations of an Advanced Carbon Capture Material: Experiments for the Inorganic Chemistry Laboratory

    Science.gov (United States)

    Wriedt, Mario; Sculley, Julian P.; Aulakh, Darpandeep; Zhou, Hong-Cai

    2016-01-01

    A simple and straightforward synthesis of an ultrastable porous metal-organic framework (MOF) based on copper(II) and a mixed N donor ligand system is described as a laboratory experiment for chemistry undergraduate students. These experiments and the resulting analysis are designed to teach students basic research tools and procedures while…

  11. Demonstration of Supervisory Control and Data Acquisition (SCADA) Virtualization Capability in the US Army Research Laboratory (ARL)/Sustaining Base Network Assurance Branch (SBNAB) US Army Cyber Analytics Laboratory (ACAL) SCADA Hardware Testbed

    Science.gov (United States)

    2015-05-01

    ARL‐CR‐0773 ● MAY 2015          US Army Research Laboratory    Demonstration of Supervisory Control and Data  Acquisition ( SCADA ...ACAL)   SCADA  Hardware Testbed     prepared by Daniel T Sullivan   Raytheon Company  22260 Pacific Blvd  Dulles, VA    and     Edward J Colbert, PhD  ICF...Laboratory    Demonstration of Supervisory Control and Data  Acquisition ( SCADA ) Virtualization Capability  in  the US Army Research Laboratory (ARL

  12. Using Instrumental Neutron Activation Analysis for geochemical analyses of terrestrial impact structures: Current analytical procedures at the University of Vienna Geochemistry Activation Analysis Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Mader, Dieter [Department of Lithospheric Research, University of Vienna, Althanstrasse 14, 1090 Vienna (Austria)], E-mail: dieter.mader@univie.ac.at; Koeberl, Christian [Department of Lithospheric Research, University of Vienna, Althanstrasse 14, 1090 Vienna (Austria)], E-mail: christian.koeberl@univie.ac.at

    2009-12-15

    The Instrumental Neutron Activation Analysis Gamma Spectroscopy Laboratory at the Department of Lithospheric Research, University of Vienna, has been upgraded in the year 2006. This paper describes the sample preparation, new instrumentation and data evaluation for hundreds of rock samples of two terrestrial impact structures. The measurement and data evaluation are done by using Genie{sup TM} 2000 and a custom-made batch software for the used analysis sequences.

  13. Optimisation of an analytical method and results from the inter-laboratory comparison of the migration of regulated substances from food packaging into the new mandatory European Union simulant for dry foodstuffs.

    Science.gov (United States)

    Jakubowska, Natalia; Beldì, Giorgia; Peychès Bach, Aurélie; Simoneau, Catherine

    2014-01-01

    This paper presents the outcome of the development, optimisation and validation at European Union level of an analytical method for using poly(2,6-diphenyl phenylene oxide--PPPO), which is stipulated in Regulation (EU) No. 10/2011, as food simulant E for testing specific migration from plastics into dry foodstuffs. Two methods for fortifying respectively PPPO and a low-density polyethylene (LDPE) film with surrogate substances that are relevant to food contact were developed. A protocol for cleaning the PPPO and an efficient analytical method were developed for the quantification of butylhydroxytoluene (BHT), benzophenone (BP), diisobutylphthalate (DiBP), bis(2-ethylhexyl) adipate (DEHA) and 1,2-cyclohexanedicarboxylic acid, diisononyl ester (DINCH) from PPPO. A protocol for a migration test from plastics using small migration cells was also developed. The method was validated by an inter-laboratory comparison (ILC) with 16 national reference laboratories for food contact materials in the European Union. This allowed for the first time data to be obtained on the precision and laboratory performance of both migration and quantification. The results showed that the validation ILC was successful even when taking into account the complexity of the exercise. The results showed that the method performance was 7-9% repeatability standard deviation (rSD) for most substances (regardless of concentration), with 12% rSD for the high level of BHT and for DiBP at very low levels. The reproducibility standard deviation results for the 16 European Union laboratories were in the range of 20-30% for the quantification from PPPO (for the three levels of concentrations of the five substances) and 15-40% from migration experiments from the fortified plastic at 60°C for 10 days and subsequent quantification. Considering the lack of data previously available in the literature, this work has demonstrated that the validation of a method is possible both for migration from a film and for

  14. Analytic Materials

    CERN Document Server

    Milton, Graeme W

    2016-01-01

    The theory of inhomogeneous analytic materials is developed. These are materials where the coefficients entering the equations involve analytic functions. Three types of analytic materials are identified. The first two types involve an integer $p$. If $p$ takes its maximum value then we have a complete analytic material. Otherwise it is incomplete analytic material of rank $p$. For two-dimensional materials further progress can be made in the identification of analytic materials by using the well-known fact that a $90^\\circ$ rotation applied to a divergence free field in a simply connected domain yields a curl-free field, and this can then be expressed as the gradient of a potential. Other exact results for the fields in inhomogeneous media are reviewed. Also reviewed is the subject of metamaterials, as these materials provide a way of realizing desirable coefficients in the equations.

  15. Analytic trigonometry

    CERN Document Server

    Bruce, William J; Maxwell, E A; Sneddon, I N

    1963-01-01

    Analytic Trigonometry details the fundamental concepts and underlying principle of analytic geometry. The title aims to address the shortcomings in the instruction of trigonometry by considering basic theories of learning and pedagogy. The text first covers the essential elements from elementary algebra, plane geometry, and analytic geometry. Next, the selection tackles the trigonometric functions of angles in general, basic identities, and solutions of equations. The text also deals with the trigonometric functions of real numbers. The fifth chapter details the inverse trigonometric functions

  16. The Marine Sciences Laboratory (MSL)

    Data.gov (United States)

    Federal Laboratory Consortium — The�Marine Sciences Laboratory sits on 140 acres of tidelands and uplands located on Sequim Bay, Washington. Key capabilities include 6,000 sq ft of analytical and...

  17. 药品实验室分析仪器验证规范的探讨%Discussion on specification for analytical instrument qualification in phar-maceutical laboratory

    Institute of Scientific and Technical Information of China (English)

    王剑; 张怡; 丁艺钊

    2014-01-01

    Analytical instrument qualification is the focus of quality management in the pharmaceutical laboratory, is key part of the good manufacturing practice (GMP) standard for pharmaceutical industry, but also the difficulty in the actual implementation process for domestic and foreign pharmaceutical industries. Based on international guides and standards, the aim of this paper is to discuss analytical instruments qualification and management for pharmaceutical laboratory. The required instrument qualification is a whole cyclical process which is composed by the activities of the different stages. Instrument manufactures, suppliers and users of the three parties should participate in this whole qual-ification process. This paper is to describe the activities of instrument qualification in three stages, from the instrument manufacturer and supplier selection to instrument installation, performance testing and approval of the instrument use, including instrument periodic verification, calibration, maintenance and daily check. This paper is to discuss the imple-mentation points of the qualification activities and records requirements at each stage. This paper approaches reference for Chinese pharmaceutical laboratory on qualification of analytical instruments, to promote laboratory quality manage-ment standards and in line with international standards.%分析仪器验证是药品实验室质量管理的重点,是符合制药业良好操作规范的关键部分,也是国内外制药行业在实施过程中的难点。本文结合国际上相关规范和标准,对药品实验室分析仪器验证要求和过程进行探讨。仪器验证是一个整体、周期性的过程,是由不同阶段的活动组成,需要仪器制造商、供应商和使用者三方共同参与。文章将仪器验证分为三个阶段进行阐述,从仪器和制造商、供应商的选择到仪器的安装、测试和批准使用,包括仪器的定期核查、校准和维护,分别

  18. Analytic geometry

    CERN Document Server

    Burdette, A C

    1971-01-01

    Analytic Geometry covers several fundamental aspects of analytic geometry needed for advanced subjects, including calculus.This book is composed of 12 chapters that review the principles, concepts, and analytic proofs of geometric theorems, families of lines, the normal equation of the line, and related matters. Other chapters highlight the application of graphing, foci, directrices, eccentricity, and conic-related topics. The remaining chapters deal with the concept polar and rectangular coordinates, surfaces and curves, and planes.This book will prove useful to undergraduate trigonometric st

  19. Dark Field Microscopy for Analytical Laboratory Courses

    Science.gov (United States)

    Augspurger, Ashley E.; Stender, Anthony S.; Marchuk, Kyle; Greenbowe, Thomas J.; Fang, Ning

    2014-01-01

    An innovative and inexpensive optical microscopy experiment for a quantitative analysis or an instrumental analysis chemistry course is described. The students have hands-on experience with a dark field microscope and investigate the wavelength dependence of localized surface plasmon resonance in gold and silver nanoparticles. Students also…

  20. Expert Systems for the Analytical Laboratory.

    Science.gov (United States)

    de Monchy, Allan R.; And Others

    1988-01-01

    Discusses two computer problem solving programs: rule-based expert systems and decision analysis expert systems. Explores the application of expert systems to automated chemical analyses. Presents six factors to consider before using expert systems. (MVL)

  1. 7 CFR 98.4 - Analytical methods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Analytical methods. 98.4 Section 98.4 Agriculture....4 Analytical methods. (a) The majority of analytical methods used by the USDA laboratories to perform analyses of meat, meat food products and MRE's are listed as follows: (1) Official Methods...

  2. 7 CFR 94.103 - Analytical methods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Analytical methods. 94.103 Section 94.103 Agriculture... POULTRY AND EGG PRODUCTS Voluntary Analyses of Egg Products § 94.103 Analytical methods. The analytical methods used by the Science and Technology Division laboratories to perform voluntary analyses for...

  3. Analytical Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    2006-06-01

    In the Analytical Microscopy group, within the National Center for Photovoltaic's Measurements and Characterization Division, we combine two complementary areas of analytical microscopy--electron microscopy and proximal-probe techniques--and use a variety of state-of-the-art imaging and analytical tools. We also design and build custom instrumentation and develop novel techniques that provide unique capabilities for studying materials and devices. In our work, we collaborate with you to solve materials- and device-related R&D problems. This sheet summarizes the uses and features of four major tools: transmission electron microscopy, scanning electron microscopy, the dual-beam focused-ion-beam workstation, and scanning probe microscopy.

  4. Analytical quadrics

    CERN Document Server

    Spain, Barry; Ulam, S; Stark, M

    1960-01-01

    Analytical Quadrics focuses on the analytical geometry of three dimensions. The book first discusses the theory of the plane, sphere, cone, cylinder, straight line, and central quadrics in their standard forms. The idea of the plane at infinity is introduced through the homogenous Cartesian coordinates and applied to the nature of the intersection of three planes and to the circular sections of quadrics. The text also focuses on paraboloid, including polar properties, center of a section, axes of plane section, and generators of hyperbolic paraboloid. The book also touches on homogenous coordi

  5. Croatian Analytical Terminology

    Directory of Open Access Journals (Sweden)

    Kastelan-Macan; M.

    2008-04-01

    Full Text Available Results of analytical research are necessary in all human activities. They are inevitable in making decisions in the environmental chemistry, agriculture, forestry, veterinary medicine, pharmaceutical industry, and biochemistry. Without analytical measurements the quality of materials and products cannot be assessed, so that analytical chemistry is an essential part of technical sciences and disciplines.The language of Croatian science, and analytical chemistry within it, was one of the goals of our predecessors. Due to the political situation, they did not succeed entirely, but for the scientists in independent Croatia this is a duty, because language is one of the most important features of the Croatian identity. The awareness of the need to introduce Croatian terminology was systematically developed in the second half of the 19th century, along with the founding of scientific societies and the wish of scientists to write their scientific works in Croatian, so that the results of their research may be applied in economy. Many authors of textbooks from the 19th and the first half of the 20th century contributed to Croatian analytical terminology (F. Rački, B. Šulek, P. Žulić, G. Pexidr, J. Domac, G. Janeček , F. Bubanović, V. Njegovan and others. M. DeŢelić published the first systematic chemical terminology in 1940, adjusted to the IUPAC recommendations. In the second half of 20th century textbooks in classic analytical chemistry were written by V. Marjanović-Krajovan, M. Gyiketta-Ogrizek, S. Žilić and others. I. Filipović wrote the General and Inorganic Chemistry textbook and the Laboratory Handbook (in collaboration with P. Sabioncello and contributed greatly to establishing the terminology in instrumental analytical methods.The source of Croatian nomenclature in modern analytical chemistry today are translated textbooks by Skoog, West and Holler, as well as by Günnzler i Gremlich, and original textbooks by S. Turina, Z.

  6. Game Analytics

    DEFF Research Database (Denmark)

    Seif El-Nasr, Magy; Drachen, Anders; Canossa, Alessandro

    2013-01-01

    Game Analytics has gained a tremendous amount of attention in game development and game research in recent years. The widespread adoption of data-driven business intelligence practices at operational, tactical and strategic levels in the game industry, combined with the integration of quantitative...

  7. Making Decisions by Analytical Chemistry

    DEFF Research Database (Denmark)

    Andersen, Jens Enevold Thaulov

    , forensics and other fields of science where analytical chemistry is the key instrument of decision making. In order to elucidate the potential origin of the statistical variations found among laboratories, a major program was undertaken including several analytical technologies where the purpose......It has been long recognized that results of analytical chemistry are not flawless, owing to the fact that professional laboratories and research laboratories analysing the same type of samples by the same type of instruments are likely to obtain significantly different results. The European....... These discrepancies are very unfortunate because erroneous conclusions may arise from an otherwise meticulous and dedicated effort of research staff. This may eventually lead to unreliable conclusions thus jeopardizing investigations of environmental monitoring, climate changes, food safety, clinical chemistry...

  8. Video Analytics

    DEFF Research Database (Denmark)

    include: re-identification, consumer behavior analysis, utilizing pupillary response for task difficulty measurement, logo detection, saliency prediction, classification of facial expressions, face recognition, face verification, age estimation, super-resolution, pose estimation, and pain recognition......This book collects the papers presented at two workshops during the 23rd International Conference on Pattern Recognition (ICPR): the Third Workshop on Video Analytics for Audience Measurement (VAAM) and the Second International Workshop on Face and Facial Expression Recognition (FFER) from Real...

  9. HYDROMECHANICS LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — Naval Academy Hydromechanics Laboratory The Naval Academy Hydromechanics Laboratory (NAHL) began operations in Rickover Hall in September 1976. The primary purpose...

  10. Bioassay Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Bioassay Laboratory is an accredited laboratory capable of conducting standardized and innovative environmental testing in the area of aquatic ecotoxicology. The...

  11. HYDROMECHANICS LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — Naval Academy Hydromechanics LaboratoryThe Naval Academy Hydromechanics Laboratory (NAHL) began operations in Rickover Hall in September 1976. The primary purpose of...

  12. Analytical mechanics

    CERN Document Server

    Helrich, Carl S

    2017-01-01

    This advanced undergraduate textbook begins with the Lagrangian formulation of Analytical Mechanics and then passes directly to the Hamiltonian formulation and the canonical equations, with constraints incorporated through Lagrange multipliers. Hamilton's Principle and the canonical equations remain the basis of the remainder of the text. Topics considered for applications include small oscillations, motion in electric and magnetic fields, and rigid body dynamics. The Hamilton-Jacobi approach is developed with special attention to the canonical transformation in order to provide a smooth and logical transition into the study of complex and chaotic systems. Finally the text has a careful treatment of relativistic mechanics and the requirement of Lorentz invariance. The text is enriched with an outline of the history of mechanics, which particularly outlines the importance of the work of Euler, Lagrange, Hamilton and Jacobi. Numerous exercises with solutions support the exceptionally clear and concise treatment...

  13. Analytical and Radiochemistry for Nuclear Forensics

    Energy Technology Data Exchange (ETDEWEB)

    Steiner, Robert Ernest [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dry, Donald E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kinman, William Scott [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Podlesak, David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Tandon, Lav [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-05-26

    Information about nonproliferation nuclear forensics, activities in forensics at Los Alamos National Laboratory, radio analytical work at LANL, radiochemical characterization capabilities, bulk chemical and materials analysis capabilities, and future interests in forensics interactions.

  14. Web Analytics

    OpenAIRE

    Mužík, Zbyněk

    2006-01-01

    Práce se zabývá problematikou měření ukazatelů souvisejících s provozem webových stránek a aplikací a technologickými prostředky k tomu sloužícími ? Web Analytics (WA). Hlavním cílem práce je otestovat a porovnat vybrané zástupce těchto nástrojů a podrobit je srovnání podle objektivních kriterií, dále také kritické zhodnocení možností WA nástrojů obecně. V první části se práce zaměřuje na popis různých způsobů měření provozu na WWW a definuje související metriky. Poskytuje také přehled dostup...

  15. Photometrics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose:The Photometrics Laboratory provides the capability to measure, analyze and characterize radiometric and photometric properties of light sources and filters,...

  16. Target Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — [Part of the ATLAS user facility.] The Physics Division operates a target development laboratory that produces targets and foils of various thickness and substrates,...

  17. Blackroom Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Enables evaluation and characterization of materials ranging from the ultraviolet to the longwave infrared (LWIR).DESCRIPTION: The Blackroom Laboratory is...

  18. Blackroom Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Enables evaluation and characterization of materials ranging from the ultraviolet to the longwave infrared (LWIR). DESCRIPTION: The Blackroom Laboratory is...

  19. Analytical applications of ion exchangers

    CERN Document Server

    Inczédy, J

    1966-01-01

    Analytical Applications of Ion Exchangers presents the laboratory use of ion-exchange resins. This book discusses the development in the analytical application of ion exchangers. Organized into 10 chapters, this book begins with an overview of the history and significance of ion exchangers for technical purposes. This text then describes the properties of ion exchangers, which are large molecular water-insoluble polyelectrolytes having a cross-linked structure that contains ionic groups. Other chapters consider the theories concerning the operation of ion-exchange resins and investigate th

  20. LABORATORY MISCONDUCT - WHAT CAN HAPPEN TO YOU?

    Science.gov (United States)

    Contracted laboratories perform a vast number of routine and special analytical services that are the foundation of decisions upon which rests the fate of the environment. Guiding these laboratories in the generation of environmental data has been the analytical protocols and ...

  1. ACL TOP血凝仪在儿科实验室的应用评价%Evaluation of ACL TOP coagulation analytical system in the laboratory of children′s hospital

    Institute of Scientific and Technical Information of China (English)

    吴跃平; 肖丽霞; 杨庆斌; 蔡德丰; 马东礼

    2014-01-01

    目的:评价 ACL TOP 血凝仪在儿科实验室的性能及应用。方法:参照 CLSI 的要求,评价 ACL TOP血凝仪的精密度、正确度、线性、抗生物干扰能力、样本携带污染率;建立 ACL TOP 血凝仪在本地区儿童的凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)的参考区间。结果:凝固法及免疫比浊法两种方法的精密度均符合厂家规定的要求;正确度实验PT、APTT、FIB的偏倚均未超出二分之一 CLIA′88规定的允许误差范围;FIB 线性测定的直线回归方程为 Y =1.0021X-0.122,R2为0.9982,符合厂家要求(r≥0.975);胆红素20 mg/dL、甘油三脂900 mg/dL、血红蛋白5 g/L 时,对 PT、APTT、TT 和 FIB 测定的影响度均小于二分之一 CLIA′88规定的允许误差范围;样本携带污染率最高为1.81%,符合厂家性能要求;本地区儿童生物参考区间:PT(9.1~13.1 s)、APTT(24.9~42.1 s)、TT(12.6~21.1 s)、FIB(1.924~4.011 g/L)。结论:ACL TOP血凝仪具有良好的精密度、正确度、线性和较低的样本携带污染率,并具较强的抗生物干扰能力,适合本实验室使用。%Objective To evaluate the performance of ACL TOP coagulation analyzer system in the laboratory of children′s hospital. Methods According to the documents of CLSI, the analytic characteristics including precision, accuracy, linearity, interference and carryover rate were examined; specimens from healthy children were collected and assayed to determine the reference range of Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Thrombin Time (TT), Fibrinogen (FIB) and D-Dimer (D-D) from children on ACL TOP. Results The within-run and between-day coefficient of variability (CV) were within an acceptable range; The accuracy deviation of PT , APTT and FIB were less than 1/2 allowed total errors

  2. Comparative analysis on continuous sampling: the laboratory analytical method and air quality automation monitoring system%连续采样-实验室分析法与空气质量自动监测系统比对分析

    Institute of Scientific and Technical Information of China (English)

    严业华

    2012-01-01

    空气质量中二氧化硫、二氧化氮、可吸入颗粒物三种污染因子用连续采样-实验室分析法与空气质量自动监测系统两种方法进行比对实验并进行原因分析。%Use two ways which are continuous sampling: the laboratory analytical method and air quality automation monitoring system to make comparative research on the three pollution factors in the air quality which includes sulfur dioxide, nitrogen dioxide, pellet and analyze the reasons.

  3. Analytical Chemistry and Measurement Science: (What Has DOE Done for Analytical Chemistry?)

    Science.gov (United States)

    Shults, W. D.

    1989-04-01

    Over the past forty years, analytical scientists within the DOE complex have had a tremendous impact on the field of analytical chemistry. This paper suggests six "high impact" research/development areas that either originated within or were brought to maturity within the DOE laboratories. "High impact" means they lead to new subdisciplines or to new ways of doing business.

  4. Hanford analytical services quality assurance requirements documents

    Energy Technology Data Exchange (ETDEWEB)

    Hyatt, J.E.

    1997-09-25

    Hanford Analytical Services Quality Assurance Requirements Document (HASQARD) is issued by the Analytical Services, Program of the Waste Management Division, US Department of Energy (US DOE), Richland Operations Office (DOE-RL). The HASQARD establishes quality requirements in response to DOE Order 5700.6C (DOE 1991b). The HASQARD is designed to meet the needs of DOE-RL for maintaining a consistent level of quality for sampling and field and laboratory analytical services provided by contractor and commercial field and laboratory analytical operations. The HASQARD serves as the quality basis for all sampling and field/laboratory analytical services provided to DOE-RL through the Analytical Services Program of the Waste Management Division in support of Hanford Site environmental cleanup efforts. This includes work performed by contractor and commercial laboratories and covers radiological and nonradiological analyses. The HASQARD applies to field sampling, field analysis, and research and development activities that support work conducted under the Hanford Federal Facility Agreement and Consent Order Tri-Party Agreement and regulatory permit applications and applicable permit requirements described in subsections of this volume. The HASQARD applies to work done to support process chemistry analysis (e.g., ongoing site waste treatment and characterization operations) and research and development projects related to Hanford Site environmental cleanup activities. This ensures a uniform quality umbrella to analytical site activities predicated on the concepts contained in the HASQARD. Using HASQARD will ensure data of known quality and technical defensibility of the methods used to obtain that data. The HASQARD is made up of four volumes: Volume 1, Administrative Requirements; Volume 2, Sampling Technical Requirements; Volume 3, Field Analytical Technical Requirements; and Volume 4, Laboratory Technical Requirements. Volume 1 describes the administrative requirements

  5. Computational Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains a number of commercial off-the-shelf and in-house software packages allowing for both statistical analysis as well as mathematical modeling...

  6. Laboratory Tests

    Science.gov (United States)

    Laboratory tests check a sample of your blood, urine, or body tissues. A technician or your doctor ... compare your results to results from previous tests. Laboratory tests are often part of a routine checkup ...

  7. Protein Laboratories in Single Location | Poster

    Science.gov (United States)

    By Andrew Stephen, Timothy Veenstra, and Gordon Whiteley, Guest Writers, and Ken Michaels, Staff Writer The Laboratory of Proteomics and Analytical Technologies (LPAT), Antibody Characterization Laboratory (ACL), and Protein Chemistry Laboratory (PCL), previously located on different floors or in different buildings, are now together on the first floor of C wing in the ATRF.

  8. Principais parâmetros biológicos avaliados em erros na fase pré-analítica de laboratórios clínicos: revisão sistemática Main biological parameters evaluated in pre-analytical phase errors at clinical laboratories: a systematic review

    Directory of Open Access Journals (Sweden)

    Vivaldo Gomes da Costa

    2012-06-01

    comprises three phases: pre-analytical, analytical and post-analytical. Most errors occur in the pre-analytical phase. Thus, their determination and corresponding assessment maximize QAP efficiency. In this study, by means of a systematic review, which comprised 14 articles, we describe the main biological variations found in the pre-analytical phase at clinical laboratories. The biological parameters described in the review included glucose, cholesterol, triglycerides, enzymes and hormones. As far as venipuncture is concerned, a common error was the prolonged use of tourniquet. The main error causes were the following: storage time, tourniquet time, phlebotomy techniques, insufficient information to patients, incorrect blood/anticoagulant ratio, inadequate tubes, contaminated samples, medication and interlaboratory alterations. Our results corroborated other studies, although we did not find other investigations that specifically evaluated changes in the pre-analytical phase due to the use of medication. The most assessed biological parameters coincided with clinical tests. Accordingly, both the implementation of an efficient QAP and the development of professional awareness may prevent laboratory inaccuracies.

  9. Analytics for Education

    Science.gov (United States)

    MacNeill, Sheila; Campbell, Lorna M.; Hawksey, Martin

    2014-01-01

    This article presents an overview of the development and use of analytics in the context of education. Using Buckingham Shum's three levels of analytics, the authors present a critical analysis of current developments in the domain of learning analytics, and contrast the potential value of analytics research and development with real world…

  10. Increasing Efficiency and Quality by Consolidation of Clinical Chemistry and Immunochemistry Systems with MODULAR ANALYTICS SWA

    OpenAIRE

    Mocarelli, Paolo; Horowitz, Gary L.; Gerthoux, Pier Mario; Cecere, Rossana; Imdahl, Roland; Ruinemans-Koerts, Janneke; Luthe, Hilmar; Calatayud, Silvia Pesudo; Salve, Marie Luisa; Kunst, Albert; McGovern, Margaret; Ng, Katherine; Stockmann, Wolfgang

    2008-01-01

    MODULAR ANALYTICS Serum Work Area (in USA Integrated MODULAR ANALYTICS, MODULAR ANALYTICS is a trademark of a member of the Roche Group) represents a further approach to automation in the laboratory medicine. This instrument combines previously introduced modular systems for the clinical chemistry and immunochemistry laboratory and allows customised combinations for various laboratory workloads. Functionality, practicability, and workflow behaviour of MODULAR ANALYTICS Serum Work Area were ev...

  11. Use of Veterinary Records To Teach Laboratory Thinking Skills in Biology.

    Science.gov (United States)

    Woolverton, Christopher J.

    1999-01-01

    Describes a laboratory protocol using clinical veterinary data that teaches the cognitive, analytical, communication, and interpersonal skills necessary for students in a biology core laboratory course. (WRM)

  12. Laboratory Building.

    Energy Technology Data Exchange (ETDEWEB)

    Herrera, Joshua M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-01

    This report is an analysis of the means of egress and life safety requirements for the laboratory building. The building is located at Sandia National Laboratories (SNL) in Albuquerque, NM. The report includes a prescriptive-based analysis as well as a performance-based analysis. Following the analysis are appendices which contain maps of the laboratory building used throughout the analysis. The top of all the maps is assumed to be north.

  13. Laboratory Building

    Energy Technology Data Exchange (ETDEWEB)

    Herrera, Joshua M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-01

    This report is an analysis of the means of egress and life safety requirements for the laboratory building. The building is located at Sandia National Laboratories (SNL) in Albuquerque, NM. The report includes a prescriptive-based analysis as well as a performance-based analysis. Following the analysis are appendices which contain maps of the laboratory building used throughout the analysis. The top of all the maps is assumed to be north.

  14. Dynamics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Dynamics Lab replicates vibration environments for every Navy platform. Testing performed includes: Flight Clearance, Component Improvement, Qualification, Life...

  15. Visualization Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Evaluates and improves the operational effectiveness of existing and emerging electronic warfare systems. By analyzing and visualizing simulation results...

  16. Propulsion Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Propulsion Lab simulates field test conditions in a controlled environment, using standardized or customized test procedures. The Propulsion Lab's 11 cells can...

  17. Chemistry Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: To conduct fundamental studies of highway materials aimed at understanding both failure mechanisms and superior performance. New standard test methods are...

  18. Psychology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This facility provides testing stations for computer-based assessment of cognitive and behavioral Warfighter performance. This 500 square foot configurable space can...

  19. Hanford transuranic analytical capability

    Energy Technology Data Exchange (ETDEWEB)

    McVey, C.B.

    1995-02-24

    With the current DOE focus on ER/WM programs, an increase in the quantity of waste samples that requires detailed analysis is forecasted. One of the prime areas of growth is the demand for DOE environmental protocol analyses of TRU waste samples. Currently there is no laboratory capacity to support analysis of TRU waste samples in excess of 200 nCi/gm. This study recommends that an interim solution be undertaken to provide these services. By adding two glove boxes in room 11A of 222S the interim waste analytical needs can be met for a period of four to five years or until a front end facility is erected at or near the 222-S facility. The yearly average of samples is projected to be approximately 600 samples. The figure has changed significantly due to budget changes and has been downgraded from 10,000 samples to the 600 level. Until these budget and sample projection changes become firmer, a long term option is not recommended at this time. A revision to this document is recommended by March 1996 to review the long term option and sample projections.

  20. Learning Laboratory.

    Science.gov (United States)

    Hay, Lyn; Callison, Daniel

    2000-01-01

    Considers the school library media center as an information learning laboratory. Topics include information literacy; Kuhlthau's Information Search Process model; inquiry theory and approach; discovery learning; process skills of laboratory science; the information scientist; attitudes of media specialists, teachers, and students; displays and Web…

  1. Clustering in analytical chemistry.

    Science.gov (United States)

    Drab, Klaudia; Daszykowski, Michal

    2014-01-01

    Data clustering plays an important role in the exploratory analysis of analytical data, and the use of clustering methods has been acknowledged in different fields of science. In this paper, principles of data clustering are presented with a direct focus on clustering of analytical data. The role of the clustering process in the analytical workflow is underlined, and its potential impact on the analytical workflow is emphasized.

  2. 10 CFR 26.155 - Laboratory personnel.

    Science.gov (United States)

    2010-01-01

    ... shall have documented scientific qualifications in analytical forensic toxicology. Minimum qualifications are as follows: (i) Certification by the appropriate State as a laboratory director in forensic or... and graduate education in biology, chemistry, and pharmacology or toxicology; or (iii) Training...

  3. Monitoring and improving the quality of the extra-analytical phase is the challenge for laboratory medicine%监测和改善分析阶段外的质量是检验医学面临的挑战

    Institute of Scientific and Technical Information of China (English)

    童清; 周睿

    2015-01-01

    国际医学实验室认可准则明确要求要监测检验全程(TTP)的质量.目前分析阶段的误差得到了有效控制;而分析前、后阶段的误差成为影响质量的主要因素.因而,监测与改善分析阶段外的质量将是我们面临的任务.监测TTP的质量,将促使临床实验室从过去局限于实验室中各阶段的管理而扩展到实验室外各环节的管理.同时,也促使我国室间质评组织机构开展分析阶段外的质量保证计划.国际临床化学和检验医学联合会已制定了临床实验室质量指标的模式.美国病理学家学会的质量探查和质量追踪计划为分析阶段外的质量监测提供了一个理想的方法.卫生部临床检验中心也依据国内外相关指南文件,并结合我国的基本国情制定了临床实验室质量控制指标体系,为分析阶段外质量保证计划的开展提供了依据.%International Standard for Medical Laboratories Accreditation demanded monitoring the quality of the total testing process (TFP).Recently, the errors in the analysis phase had been effectively controlled, while the errors in pre-and post-analytical phases still remained comparably high, and became the major factors influencing the TTP quality.Thus, monitoring and improving the quality of the extraanalytical phases became the major challenge.Monitoring the TTP quality required the laboratory staff to extend the quality management to the influential elements outside the laboratory.In addition, it also prompted the organizers of external quality assessment (EQA) in China to provide a quality assurance program for extra-analytical phases.The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) had developed a model of quality indicators.The Q-Probes and Q-Tracks programs of the College of American Pathologists provided a good practice of monitoring and improving quality for the extraanalytical phases.Based on the related international guidelines

  4. Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database

    Energy Technology Data Exchange (ETDEWEB)

    Omenn, Gilbert; States, David J.; Adamski, Marcin; Blackwell, Thomas W.; Menon, Rajasree; Hermjakob, Henning; Apweiler, Rolf; Haab, Brian B.; Simpson, Richard; Eddes, James; Kapp, Eugene; Moritz, Rod; Chan, Daniel W.; Rai, Alex J.; Admon, Arie; Aebersold, Ruedi; Eng, Jimmy K.; Hancock, William S.; Hefta, Stanley A.; Meyer, Helmut; Paik, Young-Ki; Yoo, Jong-Shin; Ping, Peipei; Pounds, Joel G.; Adkins, Joshua N.; Qian, Xiaohong; Wang, Rong; Wasinger, Valerie; Wu, Chi Yue; Zhao, Xiaohang; Zeng, Rong; Archakov, Alexander; Tsugita, Akira; Beer, Ilan; Pandey, Akhilesh; Pisano, Michael; Andrews, Philip; Tammen, Harald; Speicher, David W.; Hanash, Samir M.

    2005-08-13

    HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated advantages and limitations of many depletion, fractionation, and MS technology platforms; (2) compared PPP reference specimens of human serum and EDTA, heparin, and citrate-anticoagulated plasma; and (3) created a publicly-available knowledge base (www.bioinformatics. med.umich.edu/hupo/ppp; www.ebi.ac.uk/pride). Thirty-five participating laboratories in 13 countries submitted datasets. Working groups addressed (a) specimen stability and protein concentrations; (b) protein identifications from 18 MS/MS datasets; (c) independent analyses from raw MS-MS spectra; (d) search engine performance, subproteome analyses, and biological insights; (e) antibody arrays; and (f) direct MS/SELDI analyses. MS-MS datasets had 15 710 different International Protein Index (IPI) protein IDs; our integration algorithm applied to multiple matches of peptide sequences yielded 9504 IPI proteins identified with one or more peptides and 3020 proteins identified with two or more peptides (the Core Dataset). These proteins have been characterized with Gene Ontology, InterPro, Novartis Atlas, OMIM, and immunoassay based concentration determinations. The database permits examination of many other subsets, such as 1274 proteins identified with three or more peptides. Reverse protein to DNA matching identified proteins for 118 previously unidentified ORFs. We recommend use of plasma instead of serum, with EDTA (or citrate) for anticoagulation. To improve resolution, sensitivity and reproducibility of peptide identifications and protein matches, we recommend combinations of depletion, fractionation, and MS/MS technologies, with explicit criteria for evaluation of spectra, use of search algorithms, and integration of homologous protein matches. This Special Issue of PROTEOMICS presents papers integral to the collaborative analysis plus many reports of supplementary work on various aspects of the PPP workplan

  5. Semiconductor Electrical Measurements Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Semiconductor Electrical Measurements Laboratory is a research laboratory which complements the Optical Measurements Laboratory. The laboratory provides for Hall...

  6. Analytic Networks in Music Task Definition.

    Science.gov (United States)

    Piper, Richard M.

    For a student to acquire the conceptual systems of a discipline, the designer must reflect that structure or analytic network in his curriculum. The four networks identified for music and used in the development of the Southwest Regional Laboratory (SWRL) Music Program are the variable-value, the whole-part, the process-stage, and the class-member…

  7. Modern analytical chemistry in the contemporary world

    Science.gov (United States)

    Šíma, Jan

    2016-12-01

    Students not familiar with chemistry tend to misinterpret analytical chemistry as some kind of the sorcery where analytical chemists working as modern wizards handle magical black boxes able to provide fascinating results. However, this approach is evidently improper and misleading. Therefore, the position of modern analytical chemistry among sciences and in the contemporary world is discussed. Its interdisciplinary character and the necessity of the collaboration between analytical chemists and other experts in order to effectively solve the actual problems of the human society and the environment are emphasized. The importance of the analytical method validation in order to obtain the accurate and precise results is highlighted. The invalid results are not only useless; they can often be even fatal (e.g., in clinical laboratories). The curriculum of analytical chemistry at schools and universities is discussed. It is referred to be much broader than traditional equilibrium chemistry coupled with a simple description of individual analytical methods. Actually, the schooling of analytical chemistry should closely connect theory and practice.

  8. Modern analytical chemistry in the contemporary world

    Science.gov (United States)

    Šíma, Jan

    2016-02-01

    Students not familiar with chemistry tend to misinterpret analytical chemistry as some kind of the sorcery where analytical chemists working as modern wizards handle magical black boxes able to provide fascinating results. However, this approach is evidently improper and misleading. Therefore, the position of modern analytical chemistry among sciences and in the contemporary world is discussed. Its interdisciplinary character and the necessity of the collaboration between analytical chemists and other experts in order to effectively solve the actual problems of the human society and the environment are emphasized. The importance of the analytical method validation in order to obtain the accurate and precise results is highlighted. The invalid results are not only useless; they can often be even fatal (e.g., in clinical laboratories). The curriculum of analytical chemistry at schools and universities is discussed. It is referred to be much broader than traditional equilibrium chemistry coupled with a simple description of individual analytical methods. Actually, the schooling of analytical chemistry should closely connect theory and practice.

  9. Audio Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides an environment and facilities for auditory display research. A primary focus is the performance use of binaurally rendered 3D sound in conjunction...

  10. Elastomers Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Primary capabilities include: elastomer compounding in various sizes (micro, 3x5, 8x12, 8x15 rubber mills); elastomer curing and post curing (two 50-ton presses, one...

  11. 全国231家临床实验室23项干化学与湿化学检验项目参考区间的比较和分析%Comparison of the Reference Intervals of 2 3 Analytes between Wet Chemistry and Dry Chemistry in 2 3 1 Clinical Laboratories in China

    Institute of Scientific and Technical Information of China (English)

    钟堃; 王薇; 何法霖; 王治国

    2015-01-01

    Objective To compare the current application status of reference intervals in dry chemistry to the reference inter-vals of anlytes of wet chemistry in the same hospital.Methods By using web-based external quality assessment (EQA) software system,collecting the submitted data from the laboratories which attended national reference intervals investigation of reference intervals of analytes in dry chemistry and wet chemistry,using professional statistical software for analyzing the data,including paired-samples t test and Yates’Chi-square test.Results 231 laboratories submitted their investigation re-sults including the reference intervals of 23 analytes of dry and wet chemistry.69.6% (32/46)of reference intervals of ana-lytes in dry chemistry have significant statistical differences compared with the wet chemistry in paired-samples t tests. 80.4% (37/46)of medians of reference intervals of analytes in dry chemistry had significant statistical differences in loca-tions and distributions compared with medians of reference intervals of wet chemistry in the same institute.Conclusion The reference intervals of analytes of dry chemistry have differences compared with the wet chemistry in the same hospital.The medians of reference interval’s lower and higher limits of dry and wet chemistry have difference in locations and distribu-tions.Proposed to create our own reference intervals of dry chemistry in China.%目的:该研究拟对目前中国医院检验科干化学检验项目的参考区间与对应湿化学的参考区间进行比较,了解医院检验科干、湿化学检验项目参考区间的差异。方法采用基于 Web方式的室间质量评价(EQA)软件系统,收集参加2014年全国干化学和常规化学(湿化学)参考区间调查的实验室所上报的数据,利用配对t检验和中位数 Yates’卡方检验进行统计分析,以确定在同一医疗机构内干化学和湿化学项目的参考区间,以及上下限的中位

  12. Analytical Chemistry in Russia.

    Science.gov (United States)

    Zolotov, Yuri

    2016-09-06

    Research in Russian analytical chemistry (AC) is carried out on a significant scale, and the analytical service solves practical tasks of geological survey, environmental protection, medicine, industry, agriculture, etc. The education system trains highly skilled professionals in AC. The development and especially manufacturing of analytical instruments should be improved; in spite of this, there are several good domestic instruments and other satisfy some requirements. Russian AC has rather good historical roots.

  13. Science Update: Analytical Chemistry.

    Science.gov (United States)

    Worthy, Ward

    1980-01-01

    Briefly discusses new instrumentation in the field of analytical chemistry. Advances in liquid chromatography, photoacoustic spectroscopy, the use of lasers, and mass spectrometry are also discussed. (CS)

  14. Quality in laboratory medicine: 50years on.

    Science.gov (United States)

    Plebani, Mario

    2017-02-01

    The last 50years have seen substantial changes in the landscape of laboratory medicine: its role in modern medicine is in evolution and the quality of laboratory services is changing. The need to control and improve quality in clinical laboratories has grown hand in hand with the growth in technological developments leading to an impressive reduction of analytical errors over time. An essential cause of this impressive improvement has been the introduction and monitoring of quality indicators (QIs) such as the analytical performance specifications (in particular bias and imprecision) based on well-established goals. The evolving landscape of quality and errors in clinical laboratories moved first from analytical errors to all errors performed within the laboratory walls, subsequently to errors in laboratory medicine (including errors in test requesting and result interpretation), and finally, to a focus on errors more frequently associated with adverse events (laboratory-associated errors). After decades in which clinical laboratories have focused on monitoring and improving internal indicators of analytical quality, efficiency and productivity, it is time to shift toward indicators of total quality, clinical effectiveness and patient outcomes.

  15. Some Heterodox Analytic Philosophy

    Directory of Open Access Journals (Sweden)

    Guillermo E. Rosado Haddock

    2013-04-01

    Full Text Available Analytic philosophy has been the most influential philosophical movement in 20th century philosophy. It has surely contributed like no other movement to the elucidation and demarcation of philosophical problems. Nonetheless, the empiricist and sometimes even nominalist convictions of orthodox analytic philosophers have served them to inadequately render even philosophers they consider their own and to propound very questionable conceptions.

  16. The Analytical Hierarchy Process

    DEFF Research Database (Denmark)

    Barfod, Michael Bruhn

    2007-01-01

    The technical note gathers the theory behind the Analytical Hierarchy Process (AHP) and present its advantages and disadvantages in practical use.......The technical note gathers the theory behind the Analytical Hierarchy Process (AHP) and present its advantages and disadvantages in practical use....

  17. Teaching the Analytical Life

    Science.gov (United States)

    Jackson, Brian

    2010-01-01

    Using a survey of 138 writing programs, I argue that we must be more explicit about what we think students should get out of analysis to make it more likely that students will transfer their analytical skills to different settings. To ensure our students take analytical skills with them at the end of the semester, we must simplify the task we…

  18. News for analytical chemists

    DEFF Research Database (Denmark)

    Andersen, Jens Enevold Thaulov; Karlberg, Bo

    2009-01-01

    The EuCheMS Division of Analytical Chemistry (DAC) maintains a website with informations on groups of analytical chemistry at European universities (www.dac-euchems. org). Everyone may contribute to the database and contributors are responsible for an annual update of the information. The service...

  19. Learning Analytics Considered Harmful

    Science.gov (United States)

    Dringus, Laurie P.

    2012-01-01

    This essay is written to present a prospective stance on how learning analytics, as a core evaluative approach, must help instructors uncover the important trends and evidence of quality learner data in the online course. A critique is presented of strategic and tactical issues of learning analytics. The approach to the critique is taken through…

  20. Understanding Business Analytics

    Science.gov (United States)

    2015-01-05

    language are the limits of my mind. All I know is what I have words for.” - Ludwig Wittgenstein Defining Business Analytics The following are examples of...Michael Porter Figure 2: The analytic Process Step 2: Now that the problem statement has been defined, this needs to be reformulated into an

  1. Quo vadis, analytical chemistry?

    Science.gov (United States)

    Valcárcel, Miguel

    2016-01-01

    This paper presents an open, personal, fresh approach to the future of Analytical Chemistry in the context of the deep changes Science and Technology are anticipated to experience. Its main aim is to challenge young analytical chemists because the future of our scientific discipline is in their hands. A description of not completely accurate overall conceptions of our discipline, both past and present, to be avoided is followed by a flexible, integral definition of Analytical Chemistry and its cornerstones (viz., aims and objectives, quality trade-offs, the third basic analytical reference, the information hierarchy, social responsibility, independent research, transfer of knowledge and technology, interfaces to other scientific-technical disciplines, and well-oriented education). Obsolete paradigms, and more accurate general and specific that can be expected to provide the framework for our discipline in the coming years are described. Finally, the three possible responses of analytical chemists to the proposed changes in our discipline are discussed.

  2. European Analytical Column

    DEFF Research Database (Denmark)

    Karlberg, B.; Grasserbauer, M.; Andersen, Jens Enevold Thaulov

    2009-01-01

    The European Analytical Column has once more invited a guest columnist to give his views on various matters related to analytical chemistry in Europe. This year, we have invited Professor Manfred Grasserbauer of the Vienna University of Technology to present some of the current challenges...... for European analytical chemistry. During the period 2002–07, Professor Grasserbauer was Director of the Institute for Environment and Sustainability, Joint Research Centre of the European Commission (EC), Ispra, Italy. There is no doubt that many challenges exist at the present time for all of us representing...... a major branch of chemistry, namely analytical chemistry. The global financial crisis is affecting all branches of chemistry, but analytical chemistry, in particular, since our discipline by tradition has many close links to industry. We have already noticed decreased industrial commitment with respect...

  3. Saxton Transportation Operations Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Saxton Transportation Operations Laboratory (Saxton Laboratory) is a state-of-the-art facility for conducting transportation operations research. The laboratory...

  4. Quality assurance management plan special analytical support

    Energy Technology Data Exchange (ETDEWEB)

    Myers, M.L.

    1997-01-30

    It is the policy of Special Analytical Support (SAS) that the analytical aspects of all environmental data generated and processed in the laboratory, subject to the Environmental Protection Agency (EPA), U.S. Department of Energy (DOE), WDOE or other project specific requirements, be of known and acceptable quality. It is the intention of this QAPP to establish and assure that an effective quality controlled management system is maintained in order to meet the quality requirements of the intended use(s) of the data.

  5. Lunar laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Keaton, P.W.; Duke, M.B.

    1986-01-01

    An international research laboratory can be established on the Moon in the early years of the 21st Century. It can be built using the transportation system now envisioned by NASA, which includes a space station for Earth orbital logistics and orbital transfer vehicles for Earth-Moon transportation. A scientific laboratory on the Moon would permit extended surface and subsurface geological exploration; long-duration experiments defining the lunar environment and its modification by surface activity; new classes of observations in astronomy; space plasma and fundamental physics experiments; and lunar resource development. The discovery of a lunar source for propellants may reduce the cost of constructing large permanent facilities in space and enhance other space programs such as Mars exploration. 29 refs.

  6. Virtual Laboratories

    CERN Document Server

    Hut, P

    2006-01-01

    At the frontier of most areas in science, computer simulations play a central role. The traditional division of natural science into experimental and theoretical investigations is now completely outdated. Instead, theory, simulation, and experimentation form three equally essential aspects, each with its own unique flavor and challenges. Yet, education in computational science is still lagging far behind, and the number of text books in this area is minuscule compared to the many text books on theoretical and experimental science. As a result, many researchers still carry out simulations in a haphazard way, without properly setting up the computational equivalent of a well equipped laboratory. The art of creating such a virtual laboratory, while providing proper extensibility and documentation, is still in its infancy. A new approach is described here, Open Knowledge, as an extension of the notion of Open Source software. Besides open source code, manuals, and primers, an open knowledge project provides simul...

  7. Spectroelectrochemical Sensing of Aqueous Iron: An Experiment for Analytical Chemistry

    Science.gov (United States)

    Shtoyko, Tanya; Stuart, Dean; Gray, H. Neil

    2007-01-01

    We have designed a laboratory experiment to illustrate the use of spectroelectrochemical techniques for determination of aqueous iron. The experiment described in this article is applicable to an undergraduate laboratory course in analytical chemistry. Students are asked to fabricate spectroelectrochemical sensors, make electrochemical and optical…

  8. Analytical Chemistry Laboratory (ACL) procedure compendium. Volume 4, Organic methods

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    This interim notice covers the following: extractable organic halides in solids, total organic halides, analysis by gas chromatography/Fourier transform-infrared spectroscopy, hexadecane extracts for volatile organic compounds, GC/MS analysis of VOCs, GC/MS analysis of methanol extracts of cryogenic vapor samples, screening of semivolatile organic extracts, GPC cleanup for semivolatiles, sample preparation for GC/MS for semi-VOCs, analysis for pesticides/PCBs by GC with electron capture detection, sample preparation for pesticides/PCBs in water and soil sediment, report preparation, Florisil column cleanup for pesticide/PCBs, silica gel and acid-base partition cleanup of samples for semi-VOCs, concentrate acid wash cleanup, carbon determination in solids using Coulometrics` CO{sub 2} coulometer, determination of total carbon/total organic carbon/total inorganic carbon in radioactive liquids/soils/sludges by hot persulfate method, analysis of solids for carbonates using Coulometrics` Model 5011 coulometer, and soxhlet extraction.

  9. Analytical Chemistry Laboratory progress report for FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Green, D.W.; Heinrich, R.R.; Graczyk, D.G.; Lindahl, P.C.; Boparai, A.S.; Bass, D.A.

    1992-12-01

    The ACL activities covered IFR fuel reprocessing, corium-concrete interactions, environmental samples, wastes, WIPP support, Advanced Photon Source, H-Tc superconductors, EBWR vessel, soils, illegal drug detection, quality control, etc.

  10. Analytical Chemistry Laboratory (ACL) procedure compendium. Volume 6, Physical testing

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    This volume contains the interim change notice for physical testing. Covered are: properties of solutions, slurries, and sludges; rheological measurement with cone/plate viscometer; % solids determination; particle size distribution by laser scanning; penetration resistance of radioactive waste; operation of differential scanning calorimeter, thermogravimetric analyzer, and high temperature DTA and DSC; sodium rod for sodium bonded fuel; filling SP-100 fuel capsules; sodium filling of BEATRIX-II type capsules; removal of alkali metals with ammonia; specific gravity of highly radioactive solutions; bulk density of radioactive granular solids; purification of Li by hot gettering/filtration; and Li filling of MOTA capsules.

  11. Google analytics integrations

    CERN Document Server

    Waisberg, Daniel

    2015-01-01

    A roadmap for turning Google Analytics into a centralized marketing analysis platform With Google Analytics Integrations, expert author Daniel Waisberg shows you how to gain a more meaningful, complete view of customers that can drive growth opportunities. This in-depth guide shows not only how to use Google Analytics, but also how to turn this powerful data collection and analysis tool into a central marketing analysis platform for your company. Taking a hands-on approach, this resource explores the integration and analysis of a host of common data sources, including Google AdWords, AdSens

  12. Visual Analytics 101

    Energy Technology Data Exchange (ETDEWEB)

    Scholtz, Jean; Burtner, Edwin R.; Cook, Kristin A.

    2016-06-13

    This course will introduce the field of Visual Analytics to HCI researchers and practitioners highlighting the contributions they can make to this field. Topics will include a definition of visual analytics along with examples of current systems, types of tasks and end users, issues in defining user requirements, design of visualizations and interactions, guidelines and heuristics, the current state of user-centered evaluations, and metrics for evaluation. We encourage designers, HCI researchers, and HCI practitioners to attend to learn how their skills can contribute to advancing the state of the art of visual analytics

  13. Enzymes in Analytical Chemistry.

    Science.gov (United States)

    Fishman, Myer M.

    1980-01-01

    Presents tabular information concerning recent research in the field of enzymes in analytic chemistry, with methods, substrate or reaction catalyzed, assay, comments and references listed. The table refers to 128 references. Also listed are 13 general citations. (CS)

  14. Metoda Analytic Network Process

    OpenAIRE

    2010-01-01

    The thesis is concerned with Multi-Criteria Decision Making, in particular the Analytic Network Process method. The introductory part is dedicated to compile all the theory necessary to understand the method and utilized throughout the paper. The Analytic Hierarchy Process method is described and later generalized in the form of the ANP. Part of the paper is a description of available software products that are able to solve the ANP models. The main focus is on the application of the method, ...

  15. Encyclopedia of analytical surfaces

    CERN Document Server

    Krivoshapko, S N

    2015-01-01

    This encyclopedia presents an all-embracing collection of analytical surface classes. It provides concise definitions  and description for more than 500 surfaces and categorizes them in 38 classes of analytical surfaces. All classes are cross references to the original literature in an excellent bibliography. The encyclopedia is of particular interest to structural and civil engineers and serves as valuable reference for mathematicians.

  16. Extreme Scale Visual Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Steed, Chad A [ORNL; Potok, Thomas E [ORNL; Pullum, Laura L [ORNL; Ramanathan, Arvind [ORNL; Shipman, Galen M [ORNL; Thornton, Peter E [ORNL; Potok, Thomas E [ORNL

    2013-01-01

    Given the scale and complexity of today s data, visual analytics is rapidly becoming a necessity rather than an option for comprehensive exploratory analysis. In this paper, we provide an overview of three applications of visual analytics for addressing the challenges of analyzing climate, text streams, and biosurveilance data. These systems feature varying levels of interaction and high performance computing technology integration to permit exploratory analysis of large and complex data of global significance.

  17. Competing on analytics

    OpenAIRE

    Nagin, Gleb

    2011-01-01

    Business analytics refers to the skills, technologies, applications and practisies for continuous iterative exploration and investigation of past business performance to gain insight and drive business planning. Business analytics focuses on developing new insights and understanding of business performance based on data and statistical methods. Business intelligence traditionally focuses on using a consistent set of metrics to both measure past performance and guide business planning, which i...

  18. Intermediate algebra & analytic geometry

    CERN Document Server

    Gondin, William R

    1967-01-01

    Intermediate Algebra & Analytic Geometry Made Simple focuses on the principles, processes, calculations, and methodologies involved in intermediate algebra and analytic geometry. The publication first offers information on linear equations in two unknowns and variables, functions, and graphs. Discussions focus on graphic interpretations, explicit and implicit functions, first quadrant graphs, variables and functions, determinate and indeterminate systems, independent and dependent equations, and defective and redundant systems. The text then examines quadratic equations in one variable, system

  19. Fields with Analytic Structure

    CERN Document Server

    Cluckers, Raf

    2009-01-01

    We present a unifying theory of fields with certain classes of analytic functions, called fields with analytic structure. Both real closed fields and Henselian valued fields are considered. For real closed fields with analytic structure, o-minimality is shown. For Henselian valued fields, both the model theory and the analytic theory are developed. We give a list of examples that comprises, to our knowledge, all principal, previously studied, analytic structures on Henselian valued fields, as well as new ones. The b-minimality is shown, as well as other properties useful for motivic integration on valued fields. The paper is reminiscent of [Denef, van den Dries, "p-adic and real subanalytic sets" Ann. of Math. (2) 128 (1988) 79--138], of [Cohen, Paul J. "Decision procedures for real and p-adic fields" Comm. Pure Appl. Math. 22 (1969) 131--151, and of [Fresnel, van der Put, "Rigid analytic geometry and its applications" Progress in Mathematics, 218 Birkhauser (2004)], and unifies work by van den Dries, Haskell...

  20. Risk Management in the Clinical Laboratory

    Science.gov (United States)

    Njoroge, Sarah W

    2014-01-01

    Clinical laboratory tests play an integral role in medical decision-making and as such must be reliable and accurate. Unfortunately, no laboratory tests or devices are foolproof and errors can occur at pre-analytical, analytical and post-analytical phases of testing. Evaluating possible conditions that could lead to errors and outlining the necessary steps to detect and prevent errors before they cause patient harm is therefore an important part of laboratory testing. This can be achieved through the practice of risk management. EP23-A is a new guideline from the CLSI that introduces risk management principles to the clinical laboratory. This guideline borrows concepts from the manufacturing industry and encourages laboratories to develop risk management plans that address the specific risks inherent to each lab. Once the risks have been identified, the laboratory must implement control processes and continuously monitor and modify them to make certain that risk is maintained at a clinically acceptable level. This review summarizes the principles of risk management in the clinical laboratory and describes various quality control activities employed by the laboratory to achieve the goal of reporting valid, accurate and reliable test results. PMID:24982831

  1. [Optimization of healthcare expenditures, centralization of laboratory determinations and laboratory information accessibility].

    Science.gov (United States)

    Men'shikov, V V

    2014-04-01

    The optimization of money expenditure for healthcare is leading to the reorganization of the structure of medical organizations, to reducing of small establishments, to centralization of laboratory analyses with cessation of their performing in some hospitals and out patient offices. This tendency is based on medical (enlargement of laboratory tests spectrum) and economical (high productivity, relative reducing of net cost of laboratory determinations) reasons. But the repercussions of switch-over to centralization of laboratory analyses performance must be evaluated from the position of laboratory information accessibility tacking in account the need in express analyses for patient, situated on territories outlying from the centralized laboratory. Using of the portative analytical devices and therefore the possibility to perform the urgent analyses by non-laboratory personal in point of care and by patients themselves as a matter of self-testing can help to solve the problem of accessibility of laboratory tests in conditions of laboratory centralization in some regions.

  2. Virtual Laboratories

    Science.gov (United States)

    Hut, P.

    At the frontier of most areas in science, computer simulations playa central role. The traditional division of natural science into experimental and theoretical investigations is now completely outdated. Instead, theory, simulation, and experimentation form three equally essential aspects, each with its own unique flavor and challenges. Yet, education in computational science is still lagging far behind, and the number of text books in this area is minuscule compared to the many text books on theoretical and experimental science. As a result, many researchers still carry out simulations in a haphazard way, without properly setting up the computational equivalent of a well equipped laboratory. The art of creating such a virtual laboratory, while providing proper extensibility and documentation, is still in its infancy. A new approach is described here, Open Knowledge, as an extension of the notion of Open Source software. Besides open source code, manuals, and primers, an open knowledge project provides simulated dialogues between code developers, thus sharing not only the code, but also the motivations behind the code.

  3. Aspects of recent developments in analytical chemometrics

    Institute of Scientific and Technical Information of China (English)

    LIANG; Yizeng; WU; Hailong; SHEN; Guoli; JIANG; Jianhui; LIANG; Sheng

    2006-01-01

    Some aspects of recent developments in analytical chemometrics are discussed, in particular the developments viewed from the angle of the research efforts undertaken in authors' laboratories. The topics concerned include resolution of high-order chemical data, morphological theory and methodology for chemical signal processing, multivariate calibration and chemical pattern recognition for solving complex chemical problems, and resolution of two-way chemical data from hyphenated chromatographic instruments.

  4. Green analytical chemistry introduction to chloropropanols determination at no economic and analytical performance costs?

    Science.gov (United States)

    Jędrkiewicz, Renata; Orłowski, Aleksander; Namieśnik, Jacek; Tobiszewski, Marek

    2016-01-15

    In this study we perform ranking of analytical procedures for 3-monochloropropane-1,2-diol determination in soy sauces by PROMETHEE method. Multicriteria decision analysis was performed for three different scenarios - metrological, economic and environmental, by application of different weights to decision making criteria. All three scenarios indicate capillary electrophoresis-based procedure as the most preferable. Apart from that the details of ranking results differ for these three scenarios. The second run of rankings was done for scenarios that include metrological, economic and environmental criteria only, neglecting others. These results show that green analytical chemistry-based selection correlates with economic, while there is no correlation with metrological ones. This is an implication that green analytical chemistry can be brought into laboratories without analytical performance costs and it is even supported by economic reasons.

  5. Laboratory Activities

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Christopher F.; Serne, R. Jeffrey

    2008-01-17

    This chapter summarizes the laboratory activities performed by PNNL’s Vadose Zone Characterization Project in support of the Tank Farm Vadose Zone Program, led by CH2M HILL Hanford Group, Inc. The results of these studies are contained in numerous reports (Lindenmeier et al. 2002; Serne et al. 2002a, 2002b, 2002c, 2002d, 2002e; Lindenmeier et al. 2003; Serne et al. 2004a, 2004b; Brown et al. 2005, 2006a, 2007; Serne et al. 2007) and have generated much of the data reported in Chapter 22 (Geochemistry-Contaminant Movement), Appendix G (Geochemistry-Contaminant Movement), and Cantrell et al. (2007, SST WMA Geochemistry Data Package – in preparation). Sediment samples and characterization results from PNNL’s Vadose Zone Characterization Project are also shared with other science and technology (S&T) research projects, such as those summarized in Chapter 12 (Associated Science Activities).

  6. Doing social media analytics

    Directory of Open Access Journals (Sweden)

    Phillip Brooker

    2016-07-01

    Full Text Available In the few years since the advent of ‘Big Data’ research, social media analytics has begun to accumulate studies drawing on social media as a resource and tool for research work. Yet, there has been relatively little attention paid to the development of methodologies for handling this kind of data. The few works that exist in this area often reflect upon the implications of ‘grand’ social science methodological concepts for new social media research (i.e. they focus on general issues such as sampling, data validity, ethics, etc.. By contrast, we advance an abductively oriented methodological suite designed to explore the construction of phenomena played out through social media. To do this, we use a software tool – Chorus – to illustrate a visual analytic approach to data. Informed by visual analytic principles, we posit a two-by-two methodological model of social media analytics, combining two data collection strategies with two analytic modes. We go on to demonstrate each of these four approaches ‘in action’, to help clarify how and why they might be used to address various research questions.

  7. Analytic QCD Binding Potentials

    CERN Document Server

    Fried, H M; Grandou, T; Sheu, Y -M

    2011-01-01

    This paper applies the analytic forms of a recent non-perturbative, manifestly gauge- and Lorentz-invariant description (of the exchange of all possible virtual gluons between quarks ($Q$) and/or anti-quarks ($\\bar{Q}$) in a quenched, eikonal approximation) to extract analytic forms for the binding potentials generating a model $Q$-$\\bar{Q}$ "pion", and a model $QQQ$ "nucleon". Other, more complicated $Q$, $\\bar{Q}$ contributions to such color-singlet states may also be identified analytically. An elementary minimization technique, relevant to the ground states of such bound systems, is adopted to approximate the solutions to a more proper, but far more complicated Schroedinger/Dirac equation; the existence of possible contributions to the pion and nucleon masses due to spin, angular momentum, and "deformation" degrees of freedom is noted but not pursued. Neglecting electromagnetic and weak interactions, this analysis illustrates how the one new parameter making its appearance in this exact, realistic formali...

  8. Advances in analytical chemistry

    Science.gov (United States)

    Arendale, W. F.; Congo, Richard T.; Nielsen, Bruce J.

    1991-01-01

    Implementation of computer programs based on multivariate statistical algorithms makes possible obtaining reliable information from long data vectors that contain large amounts of extraneous information, for example, noise and/or analytes that we do not wish to control. Three examples are described. Each of these applications requires the use of techniques characteristic of modern analytical chemistry. The first example, using a quantitative or analytical model, describes the determination of the acid dissociation constant for 2,2'-pyridyl thiophene using archived data. The second example describes an investigation to determine the active biocidal species of iodine in aqueous solutions. The third example is taken from a research program directed toward advanced fiber-optic chemical sensors. The second and third examples require heuristic or empirical models.

  9. Twisted analytic torsion

    Institute of Scientific and Technical Information of China (English)

    MATHAI; Varghese

    2010-01-01

    We review the Reidemeister, Ray-Singer’s analytic torsion and the Cheeger-Mller theorem. We describe the analytic torsion of the de Rham complex twisted by a flux form introduced by the current authors and recall its properties. We define a new twisted analytic torsion for the complex of invariant differential forms on the total space of a principal circle bundle twisted by an invariant flux form. We show that when the dimension is even, such a torsion is invariant under certain deformation of the metric and the flux form. Under T-duality which exchanges the topology of the bundle and the flux form and the radius of the circular fiber with its inverse, the twisted torsion of invariant forms are inverse to each other for any dimension.

  10. Twisted Analytic Torsion

    CERN Document Server

    Mathai, Varghese

    2009-01-01

    We review the Reidemeister and Ray-Singer's analytic torsions and the Cheeger-M"uller theorem. We describe the analytic torsion of the de Rham complex twisted by a flux form introduced by the current authors and recall its properties. We define a new twisted analytic torsion for the complex of invariant differential forms on the total space of a principal circle bundle twisted by an invariant flux form. We show that when the dimension is even, such a torsion is invariant under certain deformation of the metric and the flux form. Under T-duality which exchanges the topology of the bundle and the flux form and the radius of the circular fiber with its inverse, the twisted torsions are inverse to each other for any dimensions.

  11. Competing on talent analytics.

    Science.gov (United States)

    Davenport, Thomas H; Harris, Jeanne; Shapiro, Jeremy

    2010-10-01

    Do investments in your employees actually affect workforce performance? Who are your top performers? How can you empower and motivate other employees to excel? Leading-edge companies such as Google, Best Buy, Procter & Gamble, and Sysco use sophisticated data-collection technology and analysis to answer these questions, leveraging a range of analytics to improve the way they attract and retain talent, connect their employee data to business performance, differentiate themselves from competitors, and more. The authors present the six key ways in which companies track, analyze, and use data about their people-ranging from a simple baseline of metrics to monitor the organization's overall health to custom modeling for predicting future head count depending on various "what if" scenarios. They go on to show that companies competing on talent analytics manage data and technology at an enterprise level, support what analytical leaders do, choose realistic targets for analysis, and hire analysts with strong interpersonal skills as well as broad expertise.

  12. EPA Contract Laboratory Program Statement of Work for Inorganic Superfund Methods Multi-Media, Multi-Concentration ISM02.2

    Science.gov (United States)

    This document contains analytical methods for the analysis of metals and cyanide in environmental samples. It also contains contractual requirements for laboratories participating in Superfund's Contract Laboratory Program.

  13. EPA Contract Laboratory Program Statement of Work for Inorganic Superfund Methods Multi-Media, Multi-Concentration ISM02.3

    Science.gov (United States)

    This document contains analytical methods for the analysis of metals and cyanide in environmental samples. It also contains contractual requirements for laboratories participating in Superfund's Contract Laboratory Program.

  14. Social network data analytics

    CERN Document Server

    Aggarwal, Charu C

    2011-01-01

    Social network analysis applications have experienced tremendous advances within the last few years due in part to increasing trends towards users interacting with each other on the internet. Social networks are organized as graphs, and the data on social networks takes on the form of massive streams, which are mined for a variety of purposes. Social Network Data Analytics covers an important niche in the social network analytics field. This edited volume, contributed by prominent researchers in this field, presents a wide selection of topics on social network data mining such as Structural Pr

  15. Analytic Hilbert modules

    CERN Document Server

    Chen, Xiaoman

    2003-01-01

    The seminal 1989 work of Douglas and Paulsen on the theory of analytic Hilbert modules precipitated a number of major research efforts. This in turn led to some intriguing and valuable results, particularly in the areas of operator theory and functional analysis. With the field now beginning to blossom, the time has come to collect those results under one cover. Written by two of the most active and often-cited researchers in the field, Analytic Hilbert Modules reports on the progress made by the authors and others, including the characteristic space theory, rigidity, the equivalence problem, the Arveson modules, extension theory, and reproducing Hilbert spaces on n-dimensional complex space.

  16. Foundations of predictive analytics

    CERN Document Server

    Wu, James

    2012-01-01

    Drawing on the authors' two decades of experience in applied modeling and data mining, Foundations of Predictive Analytics presents the fundamental background required for analyzing data and building models for many practical applications, such as consumer behavior modeling, risk and marketing analytics, and other areas. It also discusses a variety of practical topics that are frequently missing from similar texts. The book begins with the statistical and linear algebra/matrix foundation of modeling methods, from distributions to cumulant and copula functions to Cornish--Fisher expansion and o

  17. An analytic thomism?

    Directory of Open Access Journals (Sweden)

    Daniel Alejandro Pérez Chamorro.

    2012-12-01

    Full Text Available For 50 years the philosophers of the Anglo-Saxon analytic tradition (E. Anscombre, P. Geach, A. Kenny, P. Foot have tried to follow the Thomas Aquinas School which they use as a source to surpass the Cartesian Epistemology and to develop the virtue ethics. Recently, J. Haldane has inaugurated a program of “analytical thomism” which main result until the present has been his “theory of identity mind/world”. Nevertheless, none of Thomás’ admirers has still found the means of assimilating his metaphysics of being.

  18. Bio Engineering Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Chemistry and biology laboratoriesThe Bio Engineering Laboratory (BeL) is theonly full spectrum biotechnology capability within the Department...

  19. Bio Engineering Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Chemistry and biology laboratories The Bio Engineering Laboratory (BeL) is theonly full spectrum biotechnology capability within the Department...

  20. FOOTWEAR PERFORMANCE LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory provides biomechanical and physical analyses for both military and commercial footwear. The laboratory contains equipment that is integral to the us...

  1. Advanced Chemistry Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Chemistry laboratory The Advanced Chemistry Laboratory (ACL) is a unique facility designed for working with the most super toxic compounds known...

  2. Physical Sciences Laboratory (PSL)

    Data.gov (United States)

    Federal Laboratory Consortium — PNNL's Physical Sciences Laboratory (PSL) houses 22 research laboratories for conducting a wide-range of research including catalyst formulation, chemical analysis,...

  3. Distributed Energy Technology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Distributed Energy Technologies Laboratory (DETL) is an extension of the power electronics testing capabilities of the Photovoltaic System Evaluation Laboratory...

  4. Exploration Laboratory Analysis FY13

    Science.gov (United States)

    Krihak, Michael; Perusek, Gail P.; Fung, Paul P.; Shaw, Tianna, L.

    2013-01-01

    The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk, which is stated as the Risk of Inability to Adequately Treat an Ill or Injured Crew Member, and ExMC Gap 4.05: Lack of minimally invasive in-flight laboratory capabilities with limited consumables required for diagnosing identified Exploration Medical Conditions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability in future exploration missions. Mission architecture poses constraints on equipment and procedures that will be available to treat evidence-based medical conditions according to the Space Medicine Exploration Medical Conditions List (SMEMCL), and to perform human research studies on the International Space Station (ISS) that are supported by the Human Health and Countermeasures (HHC) element. Since there are significant similarities in the research and medical operational requirements, ELA hardware development has emerged as a joint effort between ExMC and HHC. In 2012, four significant accomplishments were achieved towards the development of exploration laboratory analysis for medical diagnostics. These achievements included (i) the development of high priority analytes for research and medical operations, (ii) the development of Level 1 functional requirements and concept of operations documentation, (iii) the selection and head-to-head competition of in-flight laboratory analysis instrumentation, and (iv) the phase one completion of the Small Business Innovation Research (SBIR) projects under the topic Smart Phone Driven Blood-Based Diagnostics. To utilize resources efficiently, the associated documentation and advanced technologies were integrated into a single ELA plan that encompasses ExMC and HHC development efforts. The requirements and high priority analytes was used in the selection of the four in-flight laboratory analysis performers. Based upon the

  5. Analytics for Customer Engagement

    NARCIS (Netherlands)

    Bijmolt, Tammo H. A.; Leeflang, Peter S. H.; Block, Frank; Eisenbeiss, Maik; Hardie, Bruce G. S.; Lemmens, Aurelie; Saffert, Peter

    2010-01-01

    In this article, we discuss the state of the art of models for customer engagement and the problems that are inherent to calibrating and implementing these models. The authors first provide an overview of the data available for customer analytics and discuss recent developments. Next, the authors di

  6. User Behavior Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Turcotte, Melissa [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Moore, Juston Shane [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-28

    User Behaviour Analytics is the tracking, collecting and assessing of user data and activities. The goal is to detect misuse of user credentials by developing models for the normal behaviour of user credentials within a computer network and detect outliers with respect to their baseline.

  7. History of analytic geometry

    CERN Document Server

    Boyer, Carl B

    2012-01-01

    Designed as an integrated survey of the development of analytic geometry, this study presents the concepts and contributions from before the Alexandrian Age through the eras of the great French mathematicians Fermat and Descartes, and on through Newton and Euler to the "Golden Age," from 1789 to 1850.

  8. Analytic number theory

    CERN Document Server

    Matsumoto, Kohji

    2002-01-01

    The book includes several survey articles on prime numbers, divisor problems, and Diophantine equations, as well as research papers on various aspects of analytic number theory such as additive problems, Diophantine approximations and the theory of zeta and L-function Audience Researchers and graduate students interested in recent development of number theory

  9. Social Learning Analytics

    Science.gov (United States)

    Buckingham Shum, Simon; Ferguson, Rebecca

    2012-01-01

    We propose that the design and implementation of effective "Social Learning Analytics (SLA)" present significant challenges and opportunities for both research and enterprise, in three important respects. The first is that the learning landscape is extraordinarily turbulent at present, in no small part due to technological drivers.…

  10. Total quality management in clinical virology laboratories.

    Science.gov (United States)

    Tibbets, M W; Gomez, R; Kannangai, R; Sridharan, G

    2006-10-01

    The diagnostic laboratories in India are progressively promoting higher standards and are moving towards accreditation and international acceptance. Hence, the concept of "Quality" will need to be understood and implemented. Total quality management (TQM) in a laboratory is an integrated program involving all laboratory staff and management. TQM is a framework to operate and it is aiming for integration, consistency, increase in efficiency and a continuous drive for improvement. A well structured clinical virology service will include serology setup, cell culture facility and capacity for molecular diagnosis. The quality of results from the laboratory is significantly influenced by many pre-analytical and post-analytical factors which needed attention. The end goal of the TQM should be to provide the best care possible for the patient.

  11. Theme: Laboratory Facilities Improvement.

    Science.gov (United States)

    Miller, Glen M.; And Others

    1993-01-01

    Includes "Laboratory Facilities Improvement" (Miller); "Remodeling Laboratories for Agriscience Instruction" (Newman, Johnson); "Planning for Change" (Mulcahy); "Laboratory Facilities Improvement for Technology Transfer" (Harper); "Facilities for Agriscience Instruction" (Agnew et al.); "Laboratory Facility Improvement" (Boren, Dwyer); and…

  12. Hanford analytical sample projections FY 1998--FY 2002

    Energy Technology Data Exchange (ETDEWEB)

    Joyce, S.M.

    1998-02-12

    Analytical Services projections are compiled for the Hanford site based on inputs from the major programs for the years 1998 through 2002. Projections are categorized by radiation level, protocol, sample matrix and program. Analyses requirements are also presented. This document summarizes the Hanford sample projections for fiscal years 1998 to 2002. Sample projections are based on inputs submitted to Analytical Services covering Environmental Restoration, Tank Waste Remediation Systems (TWRS), Solid Waste, Liquid Effluents, Spent Nuclear Fuels, Transition Projects, Site Monitoring, Industrial Hygiene, Analytical Services and miscellaneous Hanford support activities. In addition, details on laboratory scale technology (development) work, Sample Management, and Data Management activities are included. This information will be used by Hanford Analytical Services (HAS) and the Sample Management Working Group (SMWG) to assure that laboratories and resources are available and effectively utilized to meet these documented needs.

  13. Significant steps in the evolution of analytical chemistry--is the today's analytical chemistry only chemistry?

    Science.gov (United States)

    Karayannis, Miltiades I; Efstathiou, Constantinos E

    2012-12-15

    In this review the history of chemistry and specifically the history and the significant steps of the evolution of analytical chemistry are presented. In chronological time spans, covering the ancient world, the middle ages, the period of the 19th century, and the three evolutional periods, from the verge of the 19th century to contemporary times, it is given information for the progress of chemistry and analytical chemistry. During this period, analytical chemistry moved gradually from its pure empirical nature to more rational scientific activities, transforming itself to an autonomous branch of chemistry and a separate discipline. It is also shown that analytical chemistry moved gradually from the status of exclusive serving the chemical science, towards serving, the environment, health, law, almost all areas of science and technology, and the overall society. Some recommendations are also directed to analytical chemistry educators concerning the indispensable nature of knowledge of classical analytical chemistry and the associated laboratory exercises and to analysts, in general, why it is important to use the chemical knowledge to make measurements on problems of everyday life.

  14. Quality assurance management plan (QAPP) special analytical support (SAS)

    Energy Technology Data Exchange (ETDEWEB)

    LOCKREM, L.L.

    1999-05-20

    It is the policy of Special Analytical Support (SAS) that the analytical aspects of all environmental data generated and processed in the laboratory, subject to the Environmental Protection Agency (EPA), U.S. Department of Energy or other project specific requirements, be of known and acceptable quality. It is the intention of this QAPP to establish and assure that an effective quality controlled management system is maintained in order to meet the quality requirements of the intended use(s) of the data.

  15. Nuclear analytical chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Brune, D.; Forkman, B.; Persson, B.

    1984-01-01

    This book covers the general theories and techniques of nuclear chemical analysis, directed at applications in analytical chemistry, nuclear medicine, radiophysics, agriculture, environmental sciences, geological exploration, industrial process control, etc. The main principles of nuclear physics and nuclear detection on which the analysis is based are briefly outlined. An attempt is made to emphasise the fundamentals of activation analysis, detection and activation methods, as well as their applications. The book provides guidance in analytical chemistry, agriculture, environmental and biomedical sciences, etc. The contents include: the nuclear periodic system; nuclear decay; nuclear reactions; nuclear radiation sources; interaction of radiation with matter; principles of radiation detectors; nuclear electronics; statistical methods and spectral analysis; methods of radiation detection; neutron activation analysis; charged particle activation analysis; photon activation analysis; sample preparation and chemical separation; nuclear chemical analysis in biological and medical research; the use of nuclear chemical analysis in the field of criminology; nuclear chemical analysis in environmental sciences, geology and mineral exploration; and radiation protection.

  16. Multifunctional nanoparticles: Analytical prospects

    Energy Technology Data Exchange (ETDEWEB)

    Dios, Alejandro Simon de [University of Oviedo, Department of Physical and Analytical Chemistry, Faculty of Chemistry, Av. Julian Claveria, 8, 33006 Oviedo (Spain); Diaz-Garcia, Marta Elena, E-mail: medg@uniovi.es [University of Oviedo, Department of Physical and Analytical Chemistry, Faculty of Chemistry, Av. Julian Claveria, 8, 33006 Oviedo (Spain)

    2010-05-07

    Multifunctional nanoparticles are among the most exciting nanomaterials with promising applications in analytical chemistry. These applications include (bio)sensing, (bio)assays, catalysis and separations. Although most of these applications are based on the magnetic, optical and electrochemical properties of multifunctional nanoparticles, other aspects such as the synergistic effect of the functional groups and the amplification effect associated with the nanoscale dimension have also been observed. Considering not only the nature of the raw material but also the shape, there is a huge variety of nanoparticles. In this review only magnetic, quantum dots, gold nanoparticles, carbon and inorganic nanotubes as well as silica, titania and gadolinium oxide nanoparticles are addressed. This review presents a narrative summary on the use of multifuncional nanoparticles for analytical applications, along with a discussion on some critical challenges existing in the field and possible solutions that have been or are being developed to overcome these challenges.

  17. An Analytical Delay Model

    Institute of Scientific and Technical Information of China (English)

    MIN Yinghua; LI Zhongcheng

    1999-01-01

    Delay consideration has been a majorissue in design and test of high performance digital circuits. Theassumption of input signal change occurring only when all internal nodesare stable restricts the increase of clock frequency. It is no longertrue for wave pipelining circuits. However, previous logical delaymodels are based on the assumption. In addition, the stable time of arobust delay test generally depends on the longest sensitizable pathdelay. Thus, a new delay model is desirable. This paper explores thenecessity first. Then, Boolean process to analytically describe thelogical and timing behavior of a digital circuit is reviewed. Theconcept of sensitization is redefined precisely in this paper. Based onthe new concept of sensitization, an analytical delay model isintroduced. As a result, many untestable delay faults under thelogical delay model can be tested if the output waveforms can be sampledat more time points. The longest sensitizable path length is computedfor circuit design and delay test.

  18. Analytical and physical electrochemistry

    CERN Document Server

    Girault, Hubert H

    2004-01-01

    The study of electrochemistry is pertinent to a wide variety of fields, including bioenergetics, environmental sciences, and engineering sciences. In addition, electrochemistry plays a fundamental role in specific applications as diverse as the conversion and storage of energy and the sequencing of DNA.Intended both as a basic course for undergraduate students and as a reference work for graduates and researchers, Analytical and Physical Electrochemistry covers two fundamental aspects of electrochemistry: electrochemistry in solution and interfacial electrochemistry. By bringing these two subj

  19. Social Data Analytics Tool

    DEFF Research Database (Denmark)

    Hussain, Abid; Vatrapu, Ravi

    2014-01-01

    This paper presents the design, development and demonstrative case studies of the Social Data Analytics Tool, SODATO. Adopting Action Design Framework [1], the objective of SODATO [2] is to collect, store, analyze, and report big social data emanating from the social media engagement of and social...... media conversations about organizations. We report and discuss results from two demonstrative case studies that were conducted using SODATO and conclude with implications and future work....

  20. Inorganic Analytical Chemistry

    DEFF Research Database (Denmark)

    Berg, Rolf W.

    The book is a treatise on inorganic analytical reactions in aqueous solution. It covers about half of the elements in the periodic table, i.e. the most important ones : H, Li, B, C, N, O, Na, Mg, Al, P, S, Cl, K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Br, Sr, Mo, Ag, Cd, Sn, Sb, I, Ba, W,...

  1. Analytical strategies for phosphoproteomics

    DEFF Research Database (Denmark)

    Thingholm, Tine E; Jensen, Ole N; Larsen, Martin R

    2009-01-01

    sensitive and specific strategies. Today, most phosphoproteomic studies are conducted by mass spectrometric strategies in combination with phospho-specific enrichment methods. This review presents an overview of different analytical strategies for the characterization of phosphoproteins. Emphasis...... will be on the affinity methods utilized specifically for phosphoprotein and phosphopeptide enrichment prior to MS analysis, and on recent applications of these methods in cell biological applications....

  2. Encrypting Analytical Web Applications

    OpenAIRE

    Fuhry, Benny; Tighzert, Walter; Kerschbaum. Florian

    2016-01-01

    The software-as-a-service (SaaS) market is growing very fast, but still many clients are concerned about the confidentiality of their data in the cloud. Motivated hackers or malicious insiders could try to steal the clients’ data. Encryption is a potential solution, but supporting the necessary functionality also in existing applications is difficult. In this paper, we examine encrypting analytical web applications that perform extensive number processing operations in the database. Existing ...

  3. Communication Theoretic Data Analytics

    OpenAIRE

    Chen, Kwang-Cheng; Huang, Shao-Lun; Zheng, Lizhong; Poor, H. Vincent

    2015-01-01

    Widespread use of the Internet and social networks invokes the generation of big data, which is proving to be useful in a number of applications. To deal with explosively growing amounts of data, data analytics has emerged as a critical technology related to computing, signal processing, and information networking. In this paper, a formalism is considered in which data is modeled as a generalized social network and communication theory and information theory are thereby extended to data analy...

  4. Analytic Modeling of Insurgencies

    Science.gov (United States)

    2014-08-01

    point of view ; small changes in the balance of forces could lead to quick government demise. The other steady- state containment scenario involves...influenced by interests and utilities. 4.1 Carrots and Sticks An analytic model that captures the aforementioned utilitarian aspect is presented in... carrots ” x. A dynamic utility-based model is developed in [26] in which the state variables are the fractions of contrarians (supporters of the

  5. Dollarization: Analytical Issues

    OpenAIRE

    Roberto Chang; Andres Velasco

    2002-01-01

    This paper discusses major analytical aspects of dollarization and their practical implications. We develop a simple model to stress that dollarization implies the loss of independent monetary policy and of seigniorage, yet the significance of such losses can only be evaluated in conjunction with assumptions about the policymaking process. If the government is benevolent and has no credibility problems, dollarization causes a fall in welfare, which can be measured by the implied seigniorage l...

  6. ANALYTICS OF BIG DATA

    OpenAIRE

    Asst. Prof. Shubhada Talegaon

    2014-01-01

    Big Data analytics has started to impact all types of organizations, as it carries the potential power to extract embedded knowledge from big amounts of data and react according to it in real time. The current technology enables us to efficiently store and query large datasets, the focus is now on techniques that make use of the complete data set, instead of sampling. This has tremendous implications in areas like machine learning, pattern recognition and classification, senti...

  7. Supramolecular analytical chemistry.

    Science.gov (United States)

    Anslyn, Eric V

    2007-02-02

    A large fraction of the field of supramolecular chemistry has focused in previous decades upon the study and use of synthetic receptors as a means of mimicking natural receptors. Recently, the demand for synthetic receptors is rapidly increasing within the analytical sciences. These classes of receptors are finding uses in simple indicator chemistry, cellular imaging, and enantiomeric excess analysis, while also being involved in various truly practical assays of bodily fluids. Moreover, one of the most promising areas for the use of synthetic receptors is in the arena of differential sensing. Although many synthetic receptors have been shown to yield exquisite selectivities, in general, this class of receptor suffers from cross-reactivities. Yet, cross-reactivity is an attribute that is crucial to the success of differential sensing schemes. Therefore, both selective and nonselective synthetic receptors are finding uses in analytical applications. Hence, a field of chemistry that herein is entitled "Supramolecular Analytical Chemistry" is emerging, and is predicted to undergo increasingly rapid growth in the near future.

  8. High Performance Liquid Chromatography Experiments to Undergraduate Laboratories

    Science.gov (United States)

    Kissinger, Peter T.; And Others

    1977-01-01

    Reviews the principles of liquid chromatography with electrochemical detection (LCEC), an analytical technique that incorporates the advantages of both liquids chromatography and electrochemistry. Also suggests laboratory experiments using this technique. (MLH)

  9. Touring the Tomato: A Suite of Chemistry Laboratory Experiments

    Science.gov (United States)

    Sarkar, Sayantani; Chatterjee, Subhasish; Medina, Nancy; Stark, Ruth E.

    2013-01-01

    An eight-session interdisciplinary laboratory curriculum has been designed using a suite of analytical chemistry techniques to study biomaterials derived from an inexpensive source such as the tomato fruit. A logical

  10. Business analytics a practitioner's guide

    CERN Document Server

    Saxena, Rahul

    2013-01-01

    This book provides a guide to businesses on how to use analytics to help drive from ideas to execution. Analytics used in this way provides "full lifecycle support" for business and helps during all stages of management decision-making and execution.The framework presented in the book enables the effective interplay of business, analytics, and information technology (business intelligence) both to leverage analytics for competitive advantage and to embed the use of business analytics into the business culture. It lays out an approach for analytics, describes the processes used, and provides gu

  11. Inter-laboratory exercise on steroid estrogens in aqueous samples

    DEFF Research Database (Denmark)

    Heath, E.; Kosjek, T.; Andersen, Henrik Rasmus;

    2010-01-01

    to the analytical techniques applied, the accuracy and reproducibility of the analytical methods and the nature of the sample matrices. Overall, the results obtained in this inter-laboratory exercise reveal a high level of competence among the participating laboratories for the detection of steroid estrogens...... in water samples indicating that GC-MS as well as LC-MS/MS can equally be employed for the analysis of natural and synthetic hormones. (C) 2009 Elsevier Ltd All rights reserved....

  12. ANALYTIC SOLUTIONS OF MATRIX RICCATI EQUATIONS WITH ANALYTIC COEFFICIENTS

    NARCIS (Netherlands)

    Curtain, Ruth; Rodman, Leiba

    2010-01-01

    For matrix Riccati equations of platoon-type systems and of systems arising from PDEs, assuming the coefficients are analytic or rational functions in a suitable domain, analyticity of the stabilizing solution is proved under various hypotheses. General results on analytic behavior of stabilizing so

  13. Directory of Analytical Methods, Department 1820

    Energy Technology Data Exchange (ETDEWEB)

    Whan, R.E. (ed.)

    1986-01-01

    The Materials Characterization Department performs chemical, physical, and thermophysical analyses in support of programs throughout the Laboratories. The department has a wide variety of techniques and instruments staffed by experienced personnel available for these analyses, and we strive to maintain near state-of-the-art technology by continued updates. We have prepared this Directory of Analytical Methods in order to acquaint you with our capabilities and to help you identify personnel who can assist with your analytical needs. The descriptions of the various capabilities are requester-oriented and have been limited in length and detail. Emphasis has been placed on applications and limitations with notations of estimated analysis time and alternative or related techniques. A short, simplified discussion of underlying principles is also presented along with references if more detail is desired. The contents of this document have been organized in the order: bulky analysis, microanalysis, surface analysis, optical and thermal property measurements.

  14. Mars Analytical Microimager

    Science.gov (United States)

    Batory, Krzysztof J.; Govindjee; Andersen, Dale; Presley, John; Lucas, John M.; Sears, S. Kelly; Vali, Hojatollah

    Unambiguous detection of extraterrestrial nitrogenous hydrocarbon microbiology requires an instrument both to recognize potential biogenic specimens and to successfully discriminate them from geochemical settings. Such detection should ideally be in-situ and not jeopardize other experiments by altering samples. Taken individually most biomarkers are inconclusive. For example, since amino acids can be synthesized abiotically they are not always considered reliable biomarkers. An enantiomeric imbalance, which is characteristic of all terrestrial life, may be questioned because chirality can also be altered abiotically. However, current scientific understanding holds that aggregates of identical proteins or proteinaceous complexes, with their well-defined amino acid residue sequences, are indisputable biomarkers. Our paper describes the Mars Analytical Microimager, an instrument for the simultaneous imaging of generic autofluorescent biomarkers and overall morphology. Autofluorescence from ultraviolet to near-infrared is emitted by all known terrestrial biology, and often as consistent complex bands uncharacteristic of abiotic mineral luminescence. The MAM acquires morphology, and even sub-micron morphogenesis, at a 3-centimeter working distance with resolution approaching a laser scanning microscope. Luminescence is simultaneously collected via a 2.5-micron aperture, thereby permitting accurate correlation of multi-dimensional optical behavior with specimen morphology. A variable wavelength excitation source and photospectrometer serve to obtain steady-state and excitation spectra of biotic and luminescent abiotic sources. We believe this is the first time instrumentation for detecting hydrated or desiccated microbiology non-destructively in-situ has been demonstrated. We have obtained excellent preliminary detection of biota and inorganic matrix discrimination from terrestrial polar analogues, and perimetric morphology of individual magnetotactic bacteria. Proposed

  15. Analytical chemistry in space

    CERN Document Server

    Wainerdi, Richard E

    1970-01-01

    Analytical Chemistry in Space presents an analysis of the chemical constitution of space, particularly the particles in the solar wind, of the planetary atmospheres, and the surfaces of the moon and planets. Topics range from space engineering considerations to solar system atmospheres and recovered extraterrestrial materials. Mass spectroscopy in space exploration is also discussed, along with lunar and planetary surface analysis using neutron inelastic scattering. This book is comprised of seven chapters and opens with a discussion on the possibilities for exploration of the solar system by

  16. Elements of analytical dynamics

    CERN Document Server

    Kurth, Rudolph; Stark, M

    1976-01-01

    Elements of Analytical Dynamics deals with dynamics, which studies the relationship between motion of material bodies and the forces acting on them. This book is a compilation of lectures given by the author at the Georgia and Institute of Technology and formed a part of a course in Topological Dynamics. The book begins by discussing the notions of space and time and their basic properties. It then discusses the Hamilton-Jacobi theory and Hamilton's principle and first integrals. The text concludes with a discussion on Jacobi's geometric interpretation of conservative systems. This book will

  17. Analytical elements of mechanics

    CERN Document Server

    Kane, Thomas R

    2013-01-01

    Analytical Elements of Mechanics, Volume 1, is the first of two volumes intended for use in courses in classical mechanics. The books aim to provide students and teachers with a text consistent in content and format with the author's ideas regarding the subject matter and teaching of mechanics, and to disseminate these ideas. The book opens with a detailed exposition of vector algebra, and no prior knowledge of this subject is required. This is followed by a chapter on the topic of mass centers, which is presented as a logical extension of concepts introduced in connection with centroids. A

  18. Process Analytical Chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Veltkamp, David J.(VISITORS); Doherty, Steve D.(BCO); Anderson, B B.(VISITORS); Koch, Mel (University of Washington); Bond, Leonard J.(BATTELLE (PACIFIC NW LAB)); Burgess, Lloyd W.(VISITORS); Ullman, Alan H.(UNKNOWN); Bamberger, Judith A.(BATTELLE (PACIFIC NW LAB)); Greenwood, Margaret S.(BATTELLE (PACIFIC NW LAB))

    1999-06-15

    This review of process analytical chemistry is an update to the previous review on this subject published in 1995(A2). The time period covered for this review includes publications written or published from late 1994 until early 1999, with the addition of a few classic references pointing to background information critical to an understanding of a specific topic area. These older references have been critically included as established fundamental works. New topics covered in this review not previously treated as separate subjects in past reviews include sampling systems, imaging (via optical spectroscopy), and ultrasonic analysis.

  19. Local analytic geometry

    CERN Document Server

    Abhyankar, Shreeram Shankar

    1964-01-01

    This book provides, for use in a graduate course or for self-study by graduate students, a well-motivated treatment of several topics, especially the following: (1) algebraic treatment of several complex variables; (2) geometric approach to algebraic geometry via analytic sets; (3) survey of local algebra; (4) survey of sheaf theory. The book has been written in the spirit of Weierstrass. Power series play the dominant role. The treatment, being algebraic, is not restricted to complex numbers, but remains valid over any complete-valued field. This makes it applicable to situations arising from

  20. Analytic of China Cyberattack

    Directory of Open Access Journals (Sweden)

    Robert Lai

    2012-07-01

    Full Text Available China cyberattack has become aggressive, disruptive, stealthy, and sophisticated. Apparently, China’s advantage is more on the cognitive domain than technical domain since information systems security is art and science—in some case, it is more art than science. Knowledge is the best weapon for cyber warfare since one of the Sun Tze’s Art of War principles is “know your enemy”. Therefore, an analytic of China cyberattack must scrutinize the national interest, goals and philosophies, culture, worldview, and behavioral phenomena of China.

  1. Analytic of China Cyberattack

    Directory of Open Access Journals (Sweden)

    Robert Lai and Syed (Shawon Rahman

    2012-06-01

    Full Text Available China cyberattack has become aggressive, disruptive, stealthy, and sophisticated. Apparently, China’s advantage is more on the cognitive domain than technical domain since information systems security is art and science—in some case, it is more art than science. Knowledge is the best weapon for cyber warfare since one of the Sun Tze’s Art of War principles is “know your enemy”. Therefore, an analytic of China cyberattack must scrutinize the national interest, goals and philosophies, culture, worldview, and behavioral phenomena of China.

  2. Capillary electrophoresis and the clinical laboratory.

    Science.gov (United States)

    Jabeen, Rukhsana; Payne, Deborah; Wiktorowicz, John; Mohammad, Amin; Petersen, John

    2006-06-01

    Over the past 15 years, CE as an analytical tool has shown great promise in replacing many conventional clinical laboratory methods, such as electrophoresis and HPLC. CE's appeal was that it was fast, used very small amounts of sample and reagents, was extremely versatile, and was able to separate large and small analytes, whether neutral or charged. Because of this versatility, numerous methods have been developed for analytes that are of clinical interest. Other than molecular diagnostic and forensic laboratories CE has not been able to make a major impact in the United States. In contrast, in Europe and Japan an increasing number of clinical laboratories are using CE. Now that automated multicapillary instruments are commercially available along with cost-effective test kits, CE may yet be accepted as an instrument that will be routinely used in the clinical laboratories. This review will focus on areas where CE has the potential to have the greatest impact on the clinical laboratory. These include analyses of proteins found in serum and urine, hemoglobin (A1c and variants), carbohydrate-deficient transferrin, forensic and therapeutic drug screening, and molecular diagnostics.

  3. Quality and safety aspects in histopathology laboratory.

    Science.gov (United States)

    Adyanthaya, Soniya; Jose, Maji

    2013-09-01

    Histopathology is an art of analyzing and interpreting the shapes, sizes and architectural patterns of cells and tissues within a given specific clinical background and a science by which the image is placed in the context of knowledge of pathobiology, to arrive at an accurate diagnosis. To function effectively and safely, all the procedures and activities of histopathology laboratory should be evaluated and monitored accurately. In histopathology laboratory, the concept of quality control is applicable to pre-analytical, analytical and post-analytical activities. Ensuring safety of working personnel as well as environment is also highly important. Safety issues that may come up in a histopathology lab are primarily those related to potentially hazardous chemicals, biohazardous materials, accidents linked to the equipment and instrumentation employed and general risks from electrical and fire hazards. This article discusses quality management system which can ensure quality performance in histopathology laboratory. The hazards in pathology laboratories and practical safety measures aimed at controlling the dangers are also discussed with the objective of promoting safety consciousness and the practice of laboratory safety.

  4. Division of Analytical Chemistry, 1998

    DEFF Research Database (Denmark)

    Hansen, Elo Harald

    1999-01-01

    The article recounts the 1998 activities of the Division of Analytical Chemistry (DAC- formerly the Working Party on Analytical Chemistry, WPAC), which body is a division of the Federation of European Chemical Societies (FECS). Elo Harald Hansen is the Danish delegate, representing The Danish...... Chemical Society/The Society for Analytical Chemistry....

  5. Quality Indicators for Learning Analytics

    Science.gov (United States)

    Scheffel, Maren; Drachsler, Hendrik; Stoyanov, Slavi; Specht, Marcus

    2014-01-01

    This article proposes a framework of quality indicators for learning analytics that aims to standardise the evaluation of learning analytics tools and to provide a mean to capture evidence for the impact of learning analytics on educational practices in a standardised manner. The criteria of the framework and its quality indicators are based on…

  6. Learning Analytics: Readiness and Rewards

    Science.gov (United States)

    Friesen, Norm

    2013-01-01

    This position paper introduces the relatively new field of learning analytics, first by considering the relevant meanings of both "learning" and "analytics," and then by looking at two main levels at which learning analytics can be or has been implemented in educational organizations. Although integrated turnkey systems or…

  7. The analytic renormalization group

    Science.gov (United States)

    Ferrari, Frank

    2016-08-01

    Finite temperature Euclidean two-point functions in quantum mechanics or quantum field theory are characterized by a discrete set of Fourier coefficients Gk, k ∈ Z, associated with the Matsubara frequencies νk = 2 πk / β. We show that analyticity implies that the coefficients Gk must satisfy an infinite number of model-independent linear equations that we write down explicitly. In particular, we construct "Analytic Renormalization Group" linear maps Aμ which, for any choice of cut-off μ, allow to express the low energy Fourier coefficients for |νk | < μ (with the possible exception of the zero mode G0), together with the real-time correlators and spectral functions, in terms of the high energy Fourier coefficients for |νk | ≥ μ. Operating a simple numerical algorithm, we show that the exact universal linear constraints on Gk can be used to systematically improve any random approximate data set obtained, for example, from Monte-Carlo simulations. Our results are illustrated on several explicit examples.

  8. The analytic renormalization group

    Directory of Open Access Journals (Sweden)

    Frank Ferrari

    2016-08-01

    Full Text Available Finite temperature Euclidean two-point functions in quantum mechanics or quantum field theory are characterized by a discrete set of Fourier coefficients Gk, k∈Z, associated with the Matsubara frequencies νk=2πk/β. We show that analyticity implies that the coefficients Gk must satisfy an infinite number of model-independent linear equations that we write down explicitly. In particular, we construct “Analytic Renormalization Group” linear maps Aμ which, for any choice of cut-off μ, allow to express the low energy Fourier coefficients for |νk|<μ (with the possible exception of the zero mode G0, together with the real-time correlators and spectral functions, in terms of the high energy Fourier coefficients for |νk|≥μ. Operating a simple numerical algorithm, we show that the exact universal linear constraints on Gk can be used to systematically improve any random approximate data set obtained, for example, from Monte-Carlo simulations. Our results are illustrated on several explicit examples.

  9. Advanced Chemistry Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Chemistry laboratoryThe Advanced Chemistry Laboratory (ACL) is a unique facility designed for working with the most super toxic compounds known...

  10. Gun Dynamics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Gun Dynamics Laboratory is a research multi-task facility, which includes two firing bays, a high bay area and a second floor laboratory space. The high bay area...

  11. NASA Space Radiation Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory is a NASA funded facility, delivering heavy ion beams to a target area where scientists...

  12. Lincoln Laboratory Grid

    Data.gov (United States)

    Federal Laboratory Consortium — The Lincoln Laboratory Grid (LLGrid) is an interactive, on-demand parallel computing system that uses a large computing cluster to enable Laboratory researchers to...

  13. Laboratory-acquired brucellosis

    DEFF Research Database (Denmark)

    Fabiansen, C.; Knudsen, J.D.; Lebech, A.M.

    2008-01-01

    Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9......Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9...

  14. Analytical challenges in characterization of high purity materials

    Indian Academy of Sciences (India)

    K L Ramakumar

    2005-07-01

    Available analytical literature reveals that it is possible to identify a lot of procedures to carry out any determination using a plethora of analytical techniques. The fundamental analytical requirements for realizing the desired and acceptable information from a chemical analysis are representative nature of the sample, precision, accuracy, selectivity and sensitivity. These decide, to a larger extent, the selection of the most appropriate methodology in order to obtain chemical information from a system. A number of analytical methodologies are being used in the author’s laboratory for carrying out trace elemental analysis as a part of chemical quality control. Quite a good number of analytical challenges with specific reference to the characterization of high purity materials of relevance to nuclear technology were addressed and methodologies were developed for trace elemental analysis of both metallic and non-metallic constituents. A brief review of these analytical challenges and the analytical methodologies developed and also the future needs of analytical chemist are presented in this paper.

  15. Fuels Processing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s Fuels Processing Laboratory in Morgantown, WV, provides researchers with the equipment they need to thoroughly explore the catalytic issues associated with...

  16. Photovoltaic Characterization Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — NIST's PV characterization laboratory is used to measure the electrical performance and opto-electronic properties of solar cells and modules. This facility consists...

  17. Embedded Processor Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Embedded Processor Laboratory provides the means to design, develop, fabricate, and test embedded computers for missile guidance electronics systems in support...

  18. Rapid Prototyping Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC Rapid Prototyping (RP) Laboratory was established in December 1992 to provide low cost RP capabilities to the ARDEC engineering community. The Stratasys,...

  19. Coatings and Corrosion Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The mission of the Coatings and Corrosion Laboratory is to develop and analyze the effectiveness of innovative coatings test procedures while evaluating the...

  20. Geospatial Services Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: To process, store, and disseminate geospatial data to the Department of Defense and other Federal agencies. DESCRIPTION: The Geospatial Services Laboratory...

  1. Neural Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — As part of the Electrical and Computer Engineering Department and The Institute for System Research, the Neural Systems Laboratory studies the functionality of the...

  2. Thermogravimetric Analysis Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — At NETL’s Thermogravimetric Analysis Laboratory in Morgantown, WV, researchers study how chemical looping combustion (CLC) can be applied to fossil energy systems....

  3. Environmental Microbiology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Environmental Microbiology Laboratory, located in Bldg. 644 provides a dual-gas respirometer for measurement of oxygen consumption and carbon dioxide evolution...

  4. Laboratory of Chemical Physics

    Data.gov (United States)

    Federal Laboratory Consortium — Current research in the Laboratory of Chemical Physics is primarily concerned with experimental, theoretical, and computational problems in the structure, dynamics,...

  5. Research Combustion Laboratory (RCL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Research Combustion Laboratory (RCL) develops aerospace propulsion technology by performing tests on propulsion components and materials. Altitudes up to 137,000...

  6. COGNITIVE PERFORMANCE LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory conducts basic and applied human research studies to characterize cognitive performance as influenced by militarily-relevant contextual and physical...

  7. Acoustic Technology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains an electro-magnetic worldwide data collection and field measurement capability in the area of acoustic technology. Outfitted by NASA Langley...

  8. Tactical Systems Integration Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Tactical Systems Integration Laboratory is used to design and integrate computer hardware and software and related electronic subsystems for tactical vehicles....

  9. Combustion Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Combustion Research Laboratory facilitates the development of new combustion systems or improves the operation of existing systems to meet the Army's mission for...

  10. Sandia National Laboratories

    Data.gov (United States)

    Federal Laboratory Consortium — For more than 60 years, Sandia has delivered essential science and technology to resolve the nation's most challenging security issues.Sandia National Laboratories...

  11. Vehicle Development Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports the development of prototype deployment platform vehicles for offboard countermeasure systems. DESCRIPTION: The Vehicle Development Laboratory is...

  12. Central Laboratories Services

    Data.gov (United States)

    Federal Laboratory Consortium — The TVA Central Laboratories Services is a comprehensive technical support center, offering you a complete range of scientific, engineering, and technical services....

  13. Wireless Emulation Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Wireless Emulation Laboratory (WEL) is a researchtest bed used to investigate fundamental issues in networkscience. It is a research infrastructure that emulates...

  14. Space Weather Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Space Weather Computational Laboratory is a Unix and PC based modeling and simulation facility devoted to research analysis of naturally occurring electrically...

  15. Composites Characterization Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose of the Composites Characterization Laboratory is to investigate new and/or modified matrix materials and fibers for advanced composite applications both...

  16. Vehicle Development Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports the development of prototype deployment platform vehicles for offboard countermeasure systems.DESCRIPTION: The Vehicle Development Laboratory is...

  17. Engineered Natural Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — With its pressure vessels that simulate the pressures and temperatures found deep underground, NETL’s Engineered Natural Systems Laboratory in Pittsburgh, PA, gives...

  18. Virtual Training Devices Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Virtual Training Devices (VTD) Laboratory at the Life Cycle Software Engineering Center, Picatinny Arsenal, provides a software testing and support environment...

  19. Advanced Manufacturing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Manufacturing Laboratory at the University of Maryland provides the state of the art facilities for realizing next generation products and educating the...

  20. Intelligent Optics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Intelligent Optics Laboratory supports sophisticated investigations on adaptive and nonlinear optics; advancedimaging and image processing; ground-to-ground and...

  1. Semiconductor Laser Measurements Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Semiconductor Laser Measurements Laboratory is equipped to investigate and characterize the lasing properties of semiconductor diode lasers. Lasing features such...

  2. Optical Remote Sensing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Optical Remote Sensing Laboratory deploys rugged, cutting-edge electro-optical instrumentation for the collection of various event signatures, with expertise in...

  3. FOOD SAFETY TESTING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory develops screening assays, tests and modifies biosensor equipment, and optimizes food safety testing protocols for the military and civilian sector...

  4. Atmospheric Measurements Laboratory (AML)

    Data.gov (United States)

    Federal Laboratory Consortium — The Atmospheric Measurements Laboratory (AML) is one of the nation's leading research facilities for understanding aerosols, clouds, and their interactions. The AML...

  5. Pre-analytic variability in cardiovascular biomarker testing.

    Science.gov (United States)

    Cemin, Roberto; Daves, Massimo

    2015-10-01

    The impact of laboratory medicine on clinical cardiology has dramatically increased over the years and a lot of cardiovascular biomarkers have been recently proposed. In order to avoid clinical mistakes, physicians should be well aware of all the aspects, which could affect the quality of laboratory results, remembering that pre-analytic variability is an often overlooked significant source of bias, determining the vast majority of laboratory errors. This review addresses the determinants of pre-analitycal variability in cardiovascular biomarker testing, focusing on the most widespread biomarkers, which are cardiac troponins and natriuretic peptides.

  6. Tensions in the Biology Laboratory: What Are They?

    Science.gov (United States)

    Tan, Aik-Ling

    2008-01-01

    The purpose of this paper is to identify tensions in teacher-student interaction in a high school biology laboratory. Using micro-analytic analysis of classroom talk, the interaction between the students and a teacher working in the biology laboratory session on "Reproduction in Plants" is studied. The two tensions highlighted here are…

  7. Normality in analytical psychology.

    Science.gov (United States)

    Myers, Steve

    2013-12-01

    Although C.G. Jung's interest in normality wavered throughout his career, it was one of the areas he identified in later life as worthy of further research. He began his career using a definition of normality which would have been the target of Foucault's criticism, had Foucault chosen to review Jung's work. However, Jung then evolved his thinking to a standpoint that was more aligned to Foucault's own. Thereafter, the post Jungian concept of normality has remained relatively undeveloped by comparison with psychoanalysis and mainstream psychology. Jung's disjecta membra on the subject suggest that, in contemporary analytical psychology, too much focus is placed on the process of individuation to the neglect of applications that consider collective processes. Also, there is potential for useful research and development into the nature of conflict between individuals and societies, and how normal people typically develop in relation to the spectrum between individuation and collectivity.

  8. Analytic device including nanostructures

    KAUST Repository

    Di, Fabrizio, E.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  9. Analytics for Metabolic Engineering.

    Science.gov (United States)

    Petzold, Christopher J; Chan, Leanne Jade G; Nhan, Melissa; Adams, Paul D

    2015-01-01

    Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to parts with well-defined performance metrics that can be readily applied in vastly different contexts with predictable effects. As the field now stands, research depends greatly on analytical tools that assay target molecules, transcripts, proteins, and metabolites across different hosts and pathways. Screening technologies yield specific information for many thousands of strain variants, while deep omics analysis provides a systems-level view of the cell factory. Efforts focused on a combination of these analyses yield quantitative information of dynamic processes between parts and the host chassis that drive the next engineering steps. Overall, the data generated from these types of assays aid better decision-making at the design and strain construction stages to speed progress in metabolic engineering research.

  10. Big Data Analytics

    Indian Academy of Sciences (India)

    2016-08-01

    The volume and variety of data being generated using computersis doubling every two years. It is estimated that in 2015,8 Zettabytes (Zetta=1021) were generated which consistedmostly of unstructured data such as emails, blogs, Twitter,Facebook posts, images, and videos. This is called big data. Itis possible to analyse such huge data collections with clustersof thousands of inexpensive computers to discover patterns inthe data that have many applications. But analysing massiveamounts of data available in the Internet has the potential ofimpinging on our privacy. Inappropriate analysis of big datacan lead to misleading conclusions. In this article, we explainwhat is big data, how it is analysed, and give some case studiesillustrating the potentials and pitfalls of big data analytics.

  11. ANALYTICS OF BIG DATA

    Directory of Open Access Journals (Sweden)

    Prof. Shubhada Talegaon

    2015-10-01

    Full Text Available Big Data analytics has started to impact all types of organizations, as it carries the potential power to extract embedded knowledge from big amounts of data and react according to it in real time. The current technology enables us to efficiently store and query large datasets, the focus is now on techniques that make use of the complete data set, instead of sampling. This has tremendous implications in areas like machine learning, pattern recognition and classification, sentiment analysis, social networking analysis to name a few. Therefore, there are a number of requirements for moving beyond standard data mining technique. Purpose of this paper is to understand various techniques to analysis data.

  12. [ISO 15189 accreditation in clinical microbiology laboratory: general concepts and the status in our laboratory].

    Science.gov (United States)

    Akyar, Işin

    2009-10-01

    One important trend in the laboratory profession and quality management is the global convergence of laboratory operations. The goal of an accredited medical laboratory is to continue "offering useful laboratory service for diagnosis and treatment of the patients and also aid to the health of the nation". An accredited clinical laboratory is managed by a quality control system, it is competent technically and the laboratory service meets the needs of all its patients and physicians by taking the responsibility of all the medical tests and therapies. For this purpose, ISO 15189 international standard has been prepared by 2003. ISO 15189 standard is originated from the arrangement of ISO 17025 and ISO 9001:2000 standards. Many countries such as England, Germany, France, Canada and Australia have preferred ISO 15189 as their own laboratory accreditation programme, meeting all the requirements of their medical laboratories. The accreditation performance of a clinical microbiology laboratory is mainly based on five essential points; preanalytical, analytical, postanalytical, quality control programmes (internal, external, interlaboratory) and audits (internal, external). In this review article, general concepts on ISO 15189 accreditation standards for the clinical microbiology laboratories have been summarized and the status of a private laboratory (Acibadem LabMed, Istanbul) in Turkey has been discussed.

  13. 77 FR 12862 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-03-02

    ..., a Division of LabOne, Inc.). Maxxam Analytics,* 6740 Campobello Road, Mississauga, ON, Canada L5N 2L8, 905-817-5700, (Formerly: Maxxam Analytics Inc., NOVAMANN (Ontario), Inc.). * The Standards..., Clinical Chemistry Division; UTMB Pathology-Toxicology Laboratory). Pacific Toxicology Laboratories,...

  14. Validation of analytical methods

    Directory of Open Access Journals (Sweden)

    Xavier Rius, F.

    2002-03-01

    Full Text Available In this paper we shall discuss the concept of method validation, describe the various elements and explain its close relationship with fitness for purpose. Method validation is based on the assumption that a series of requirements are fulfilled and we shall explain how these requirements are selected, the way in which evidence is supplied and what work has to be carried out in the laboratory. The basic principles of method validation and the different ways to validate a methodology, by inter-laboratory comparison or performing an in-house validation, are also described.En este artículo se discute el concepto de validación del método, se describen los elementos que la componen y se explica la fuerte relación entre la validación y las características de ajuste. El método de validación se basa en el cumplimiento de una serie de requerimientos, se explica como seleccionar esos requerimientos, la forma en que se suministran evidencias, y que trabajo se debe llevar a cabo en el laboratorio. También se describen, los principios básicos del método de validación y los diferentes caminos para validar una metodología, tanto en la comparación entre laboratorios o como cuando se lleva a cabo una validación dentro del laboratorio.

  15. Laboratory Information Systems.

    Science.gov (United States)

    Henricks, Walter H

    2015-06-01

    Laboratory information systems (LISs) supply mission-critical capabilities for the vast array of information-processing needs of modern laboratories. LIS architectures include mainframe, client-server, and thin client configurations. The LIS database software manages a laboratory's data. LIS dictionaries are database tables that a laboratory uses to tailor an LIS to the unique needs of that laboratory. Anatomic pathology LIS (APLIS) functions play key roles throughout the pathology workflow, and laboratories rely on LIS management reports to monitor operations. This article describes the structure and functions of APLISs, with emphasis on their roles in laboratory operations and their relevance to pathologists.

  16. [ABOUT UNIFICATION OF LABORATORY CRITERIA OF DIFFERENTIATION OF BACTERIAL VAGINOSIS].

    Science.gov (United States)

    Mavzutov, A R; Tsvetkova, A V; Muretdinova, L A

    2015-06-01

    The article presents analysis of laboratory criteria and classifcations used to interpret results of laboratory analysis by technique of microscopy on bacterial vaginosis or dysbacteriosis of vagina. Their advantages and restrictions are demonstrated The unified criteria of evaluation are proposed concerning results of microscopy of mucosal discharge of vagina and corresponding classification. Thereafter, three degrees of bacterial vaginosis (dysbacteriosis of vagina) are differentiated: first degree--compensated dysbacteriosis of vagina, second degree--sub compensated dysbacteriosis of vagina and third degree--decompensated dysbacteriosis of vagina. The corresponding laboratory report of physician is formulated. The proposals are presented concerning development of common unified requirements to stages (pre-analytical, analytical, post-analytical) of laboratory diagnostic of bacterial vaginosis (dysbacteriosis of vagina) with purpose of their unambiguous understanding by clinicians and hence their decision making concerning necessity and tactics of management of patient.

  17. Green Chemistry Metrics with Special Reference to Green Analytical Chemistry.

    Science.gov (United States)

    Tobiszewski, Marek; Marć, Mariusz; Gałuszka, Agnieszka; Namieśnik, Jacek

    2015-06-12

    The concept of green chemistry is widely recognized in chemical laboratories. To properly measure an environmental impact of chemical processes, dedicated assessment tools are required. This paper summarizes the current state of knowledge in the field of development of green chemistry and green analytical chemistry metrics. The diverse methods used for evaluation of the greenness of organic synthesis, such as eco-footprint, E-Factor, EATOS, and Eco-Scale are described. Both the well-established and recently developed green analytical chemistry metrics, including NEMI labeling and analytical Eco-scale, are presented. Additionally, this paper focuses on the possibility of the use of multivariate statistics in evaluation of environmental impact of analytical procedures. All the above metrics are compared and discussed in terms of their advantages and disadvantages. The current needs and future perspectives in green chemistry metrics are also discussed.

  18. Green Chemistry Metrics with Special Reference to Green Analytical Chemistry

    Directory of Open Access Journals (Sweden)

    Marek Tobiszewski

    2015-06-01

    Full Text Available The concept of green chemistry is widely recognized in chemical laboratories. To properly measure an environmental impact of chemical processes, dedicated assessment tools are required. This paper summarizes the current state of knowledge in the field of development of green chemistry and green analytical chemistry metrics. The diverse methods used for evaluation of the greenness of organic synthesis, such as eco-footprint, E-Factor, EATOS, and Eco-Scale are described. Both the well-established and recently developed green analytical chemistry metrics, including NEMI labeling and analytical Eco-scale, are presented. Additionally, this paper focuses on the possibility of the use of multivariate statistics in evaluation of environmental impact of analytical procedures. All the above metrics are compared and discussed in terms of their advantages and disadvantages. The current needs and future perspectives in green chemistry metrics are also discussed.

  19. Analytic definition of spin structure

    CERN Document Server

    Avetisyan, Zhirayr; Saveliev, Nikolai; Vassiliev, Dmitri

    2016-01-01

    We work on a parallelizable time-orientable Lorentzian 4-manifold and prove that in this case the notion of spin structure can be equivalently defined in a purely analytic fashion. Our analytic definition relies on the use of the concept of a non-degenerate two-by-two formally self-adjoint first order linear differential operator and gauge transformations of such operators. We also give an analytic definition of spin structure for the 3-dimensional Riemannian case.

  20. Rorty, Pragmatism, and Analytic Philosophy

    Directory of Open Access Journals (Sweden)

    Cheryl Misak

    2013-07-01

    Full Text Available One of Richard Rorty's legacies is to have put a Jamesian version of pragmatism on the contemporary philosophical map. Part of his argument has been that pragmatism and analytic philosophy are set against each other, with pragmatism almost having been killed off by the reigning analytic philosophy. The argument of this paper is that there is a better and more interesting reading of both the history of pragmatism and the history of analytic philosophy.

  1. Methodological practicalities in analytical generalization

    DEFF Research Database (Denmark)

    Halkier, Bente

    2011-01-01

    In this article, I argue that the existing literature on qualitative methodologies tend to discuss analytical generalization at a relatively abstract and general theoretical level. It is, however, not particularly straightforward to “translate” such abstract epistemological principles into more...... operative methodological strategies for producing analytical generalizations in research practices. Thus, the aim of the article is to contribute to the discussions among qualitatively working researchers about generalizing by way of exemplifying some of the methodological practicalities in analytical...

  2. Analytic Methods for Cosmological Likelihoods

    OpenAIRE

    Taylor, A. N.; Kitching, T. D.

    2010-01-01

    We present general, analytic methods for Cosmological likelihood analysis and solve the "many-parameters" problem in Cosmology. Maxima are found by Newton's Method, while marginalization over nuisance parameters, and parameter errors and covariances are estimated by analytic marginalization of an arbitrary likelihood function with flat or Gaussian priors. We show that information about remaining parameters is preserved by marginalization. Marginalizing over all parameters, we find an analytic...

  3. Energy Materials Research Laboratory (EMRL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Energy Materials Research Laboratory at the Savannah River National Laboratory (SRNL) creates a cross-disciplinary laboratory facility that lends itself to the...

  4. Normality in Analytical Psychology

    Directory of Open Access Journals (Sweden)

    Steve Myers

    2013-11-01

    Full Text Available Although C.G. Jung’s interest in normality wavered throughout his career, it was one of the areas he identified in later life as worthy of further research. He began his career using a definition of normality which would have been the target of Foucault’s criticism, had Foucault chosen to review Jung’s work. However, Jung then evolved his thinking to a standpoint that was more aligned to Foucault’s own. Thereafter, the post Jungian concept of normality has remained relatively undeveloped by comparison with psychoanalysis and mainstream psychology. Jung’s disjecta membra on the subject suggest that, in contemporary analytical psychology, too much focus is placed on the process of individuation to the neglect of applications that consider collective processes. Also, there is potential for useful research and development into the nature of conflict between individuals and societies, and how normal people typically develop in relation to the spectrum between individuation and collectivity.

  5. Analytics for Metabolic Engineering

    Science.gov (United States)

    Petzold, Christopher J.; Chan, Leanne Jade G.; Nhan, Melissa; Adams, Paul D.

    2015-01-01

    Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to parts with well-defined performance metrics that can be readily applied in vastly different contexts with predictable effects. As the field now stands, research depends greatly on analytical tools that assay target molecules, transcripts, proteins, and metabolites across different hosts and pathways. Screening technologies yield specific information for many thousands of strain variants, while deep omics analysis provides a systems-level view of the cell factory. Efforts focused on a combination of these analyses yield quantitative information of dynamic processes between parts and the host chassis that drive the next engineering steps. Overall, the data generated from these types of assays aid better decision-making at the design and strain construction stages to speed progress in metabolic engineering research. PMID:26442249

  6. Analytics for metabolic engineering

    Directory of Open Access Journals (Sweden)

    Christopher J Petzold

    2015-09-01

    Full Text Available Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to parts with well-defined performance metrics that can be readily applied in vastly different contexts with predictable effects. As the field now stands, research depends greatly on analytical tools that assay target molecules, transcripts, proteins, and metabolites across different hosts and pathways. Screening technologies yield specific information for many thousands of strain variants while deep omics analysis provide a systems-level view of the cell factory. Efforts focused on a combination of these analyses yield quantitative information of dynamic processes between parts and the host chassis that drive the next engineering steps. Overall, the data generated from these types of assays aid better decision-making at the design and strain construction stages to speed progress in metabolic engineering research.

  7. Analytics for managers with Excel

    CERN Document Server

    Bell, Peter C

    2013-01-01

    Analytics is one of a number of terms which are used to describe a data-driven more scientific approach to management. Ability in analytics is an essential management skill: knowledge of data and analytics helps the manager to analyze decision situations, prevent problem situations from arising, identify new opportunities, and often enables many millions of dollars to be added to the bottom line for the organization.The objective of this book is to introduce analytics from the perspective of the general manager of a corporation. Rather than examine the details or attempt an encyclopaedic revie

  8. Fifty years of continuous improvement: (What has DOE done for analytical chemistry?)

    Energy Technology Data Exchange (ETDEWEB)

    Shults, W.D.

    1993-11-01

    Over the past fifty years, analytical scientist within the DOE complex have had a tremendous impact on the field of analytical chemistry. This paper suggests six ``high impact`` research/development areas that either originated within or were brought to maturity within the DOE laboratories. ``High impact`` means they lead to new subdisciplines or to new ways of doing business.

  9. Median of patient results as a tool for assessment of analytical stability

    DEFF Research Database (Denmark)

    Jørgensen, Lars Mønster; Hansen, Steen Ingemann; Petersen, Per Hyltoft;

    2015-01-01

    BACKGROUND: In spite of the well-established external quality assessment and proficiency testing surveys of analytical quality performance in laboratory medicine, a simple tool to monitor the long-term analytical stability as a supplement to the internal control procedures is often needed. METHOD...

  10. Bias Assessment of General Chemistry Analytes using Commutable Samples.

    Science.gov (United States)

    Koerbin, Gus; Tate, Jillian R; Ryan, Julie; Jones, Graham Rd; Sikaris, Ken A; Kanowski, David; Reed, Maxine; Gill, Janice; Koumantakis, George; Yen, Tina; St John, Andrew; Hickman, Peter E; Simpson, Aaron; Graham, Peter

    2014-11-01

    Harmonisation of reference intervals for routine general chemistry analytes has been a goal for many years. Analytical bias may prevent this harmonisation. To determine if analytical bias is present when comparing methods, the use of commutable samples, or samples that have the same properties as the clinical samples routinely analysed, should be used as reference samples to eliminate the possibility of matrix effect. The use of commutable samples has improved the identification of unacceptable analytical performance in the Netherlands and Spain. The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) has undertaken a pilot study using commutable samples in an attempt to determine not only country specific reference intervals but to make them comparable between countries. Australia and New Zealand, through the Australasian Association of Clinical Biochemists (AACB), have also undertaken an assessment of analytical bias using commutable samples and determined that of the 27 general chemistry analytes studied, 19 showed sufficiently small between method biases as to not prevent harmonisation of reference intervals. Application of evidence based approaches including the determination of analytical bias using commutable material is necessary when seeking to harmonise reference intervals.

  11. Chemiluminescence microarrays in analytical chemistry: a critical review.

    Science.gov (United States)

    Seidel, Michael; Niessner, Reinhard

    2014-09-01

    Multi-analyte immunoassays on microarrays and on multiplex DNA microarrays have been described for quantitative analysis of small organic molecules (e.g., antibiotics, drugs of abuse, small molecule toxins), proteins (e.g., antibodies or protein toxins), and microorganisms, viruses, and eukaryotic cells. In analytical chemistry, multi-analyte detection by use of analytical microarrays has become an innovative research topic because of the possibility of generating several sets of quantitative data for different analyte classes in a short time. Chemiluminescence (CL) microarrays are powerful tools for rapid multiplex analysis of complex matrices. A wide range of applications for CL microarrays is described in the literature dealing with analytical microarrays. The motivation for this review is to summarize the current state of CL-based analytical microarrays. Combining analysis of different compound classes on CL microarrays reduces analysis time, cost of reagents, and use of laboratory space. Applications are discussed, with examples from food safety, water safety, environmental monitoring, diagnostics, forensics, toxicology, and biosecurity. The potential and limitations of research on multiplex analysis by use of CL microarrays are discussed in this review.

  12. Large-scale data analytics

    CERN Document Server

    Gkoulalas-Divanis, Aris

    2014-01-01

    Provides cutting-edge research in large-scale data analytics from diverse scientific areas Surveys varied subject areas and reports on individual results of research in the field Shares many tips and insights into large-scale data analytics from authors and editors with long-term experience and specialization in the field

  13. [Photonic crystals for analytical chemistry].

    Science.gov (United States)

    Chen, Yi; Li, Jincheng

    2009-09-01

    Photonic crystals, originally created to control the transmission of light, have found their increasing value in the field of analytical chemistry and are probable to become a hot research area soon. This review is hence composed, focusing on their analytical chemistry-oriented applications, including especially their use in chromatography, capillary- and chip-based electrophoresis.

  14. Analytic Geometry, A Tentative Guide.

    Science.gov (United States)

    Helwig, G. Alfred; And Others

    This teacher's guide for a semester course in analytic geometry is based on the text "Analytic Geometry" by W. K. Morrill. Included is a daily schedule of suggested topics and homework assignments. Specific teaching hints are also given. The content of the course includes point and plane vectors, straight lines, point and space vectors, planes,…

  15. Real Analytic Machines and Degrees

    CERN Document Server

    Gärtner, Tobias; 10.4204/EPTCS.24.12

    2010-01-01

    We study and compare in two degree-theoretic ways (iterated Halting oracles analogous to Kleene's arithmetical hierarchy and the Borel hierarchy of descriptive set theory) the capabilities and limitations of three models of analytic computation: BSS machines (aka real-RAM) and strongly/weakly analytic machines as introduced by Hotz et. al. (1995).

  16. Graphing techniques for materials laboratory using Excel

    Science.gov (United States)

    Kundu, Nikhil K.

    1994-01-01

    Engineering technology curricula stress hands on training and laboratory practices in most of the technical courses. Laboratory reports should include analytical as well as graphical evaluation of experimental data. Experience shows that many students neither have the mathematical background nor the expertise for graphing. This paper briefly describes the procedure and data obtained from a number of experiments such as spring rate, stress concentration, endurance limit, and column buckling for a variety of materials. Then with a brief introduction to Microsoft Excel the author explains the techniques used for linear regression and logarithmic graphing.

  17. Analytic Approach to Perturbative QCD

    CERN Document Server

    Magradze, B

    2000-01-01

    The two-loop invariant (running) coupling of QCD is written in terms of the Lambert W function. The analyticity structure of the coupling in the complex Q^2-plane is established. The corresponding analytic coupling is reconstructed via a dispersion relation. We also consider some other approximations to the QCD beta-function, when the corresponding couplings are solved in terms of the Lambert function. The Landau gauge gluon propagator has been considered in the renormalization group invariant analytic approach (IAA). It is shown that there is a nonperturbative ambiguity in determination of the anomalous dimension function of the gluon field. Several analytic solutions for the propagator at the one-loop order are constructed. Properties of the obtained analytical solutions are discussed.

  18. Analytical performance specifications for EQA schemes - need for harmonisation.

    Science.gov (United States)

    Dallas Jones, Graham Ross

    2015-05-01

    External Quality Assurance (EQA) is a vital tool in laboratory medicine to assess individual laboratory analytical performance and also the differences between the results from different laboratories. This information is also useful for professional bodies and manufacturers as part of post-market surveillance. The process involves the measurement of one or more samples by many laboratories and then assessment of the results. Individual results are generally assessed by how far they lie from a target, which may be established using reference methods or a median of some or all of the submitted results. The distance of a result from the target is compared with analytical performance specifications in order to assess the analytical quality. One of the uses of the Stockholm hierarchy of performance goals is to set the performance specifications for analysis of EQA results. Fifteen years after the Stockholm consensus meeting, EQA analytical performance specifications appear to still vary widely between EQA providers. This can be due to a range of factors, including the rationale for setting the criteria, the expected response to a failure to meet the specified performance, the clinical meaning behind meeting the specifications, and the possible need for further analytical improvements. There are also differences in the models chosen to set the criteria, usually either state of the art or biological variation, and then differences in how these are applied. While harmonisation of EQA performance specifications may be some time off, all EQA providers should define the nature of their specifications and the basis for their selection and make this information available to customers.

  19. Comparison and Analysis of the Reference Intervals of 9 Serum Routine Chemical Analytes between the Current Application of Clinical Laboratories and the Latest Health Industrial Standards Draft for Approval%国内临床化学9项常规项目参考区间与即将发布的卫生行业标准的比较和分析

    Institute of Scientific and Technical Information of China (English)

    钟堃; 王薇; 何法霖; 王治国

    2015-01-01

    目的:对全国医院检验科常规化学检验项目的参考区间进行调查,并与即将发布的卫生行业标准进行比较。方法采用基于 Web 方式的室间质量评价(EQA)软件系统,收集2012年度参加全国常规化学参考区间调查的实验室所上报的数据,使用专业统计软件对数据进行统计分析。结果共385家实验室回报了调查结果。在即将发布的卫生行业标准所涉及的检验项目中,绝大多数项目不分组或未给出分组时所使用的参考区间与行业标准相比较都存在显著统计学差异[t=-55.435~17.070,P <0.05,占86.1%(31/36)]。只有较少的实验室对参考区间进行了分组(约20%),部分实验室的分组规则与行业标准有一定的差异,与行业标准分组相同的实验室所给出的参考区间与行业标准相比也多存在极显著统计学差异[t=-39.365~13.155,P <0.01,占62.5%(10/16)]。结论即将发布参考区间与实际工作中所应用的参考区间差异较大,推广已经建立的具有权威性的临床常用生化检验项目参考区间很有必要在实际工作中使用行业标准所给出的参考区间前应进行参考区间的评估和验证。%Objective To investigate the current application status of reference intervals in routine chemistry and compare with the current health industry standards draft for approval.Methods By using web-based external quality assessment (EQA)software system,collected the submitted data from the laboratories which attended national reference intervals inves-tigation,used professional statistical software to analyze the data.Results 385 laboratories had submitted the investigation results.The vast majority of the analytes of attended laboratories had significant statistical differences in comparison with the health industry standards draft for approval in no grouping and not filled groups[t = - 55.435 ~ 17.070,P < 0.05, 86

  20. Biomass Compositional Analysis Laboratory (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2014-07-01

    At the Biomass Compositional Analysis Laboratory, NREL scientists have more than 20 years of experience supporting the biomass conversion industry. They develop, refine, and validate analytical methods to determine the chemical composition of biomass samples before, during, and after conversion processing. These high-quality compositional analysis data are used to determine feedstock compositions as well as mass balances and product yields from conversion processes.

  1. Synergistic relationships between Analytical Chemistry and written standards.

    Science.gov (United States)

    Valcárcel, Miguel; Lucena, Rafael

    2013-07-25

    This paper describes the mutual impact of Analytical Chemistry and several international written standards (norms and guides) related to knowledge management (CEN-CWA 14924:2004), social responsibility (ISO 26000:2010), management of occupational health and safety (OHSAS 18001/2), environmental management (ISO 14001:2004), quality management systems (ISO 9001:2008) and requirements of the competence of testing and calibration laboratories (ISO 17025:2004). The intensity of this impact, based on a two-way influence, is quite different depending on the standard considered. In any case, a new and fruitful approach to Analytical Chemistry based on these relationships can be derived.

  2. Product Evaluation Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory offers the services of highly trained and experienced specialists that have a full complement of measuring equipment. It is equipped with two optical...

  3. Aquatic Research Laboratory (ARL)

    Data.gov (United States)

    Federal Laboratory Consortium — Columbia River and groundwater well water sources are delivered to the Aquatic Research Laboratory (ARL), where these resources are used to conduct research on fish...

  4. Laboratory of Biological Modeling

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory of Biological Modeling is defined by both its methodologies and its areas of application. We use mathematical modeling in many forms and apply it to...

  5. Laboratory of Biological Modeling

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory of Biological Modeling is defined by both its methodologies and its areas of application. We use mathematical modeling in many forms and apply it to a...

  6. Los Alamos National Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Lab has a proud history and heritage of almost 70 years of science and innovation. The people at the Laboratory work on advanced technologies to provide the best...

  7. FLEXIBLE FOOD PACKAGING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains equipment to fabricate and test prototype packages of many types and sizes (e.g., bags, pouches, trays, cartons, etc.). This equipment can...

  8. Mechanical Testing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s Mechanical Testing Laboratory in Albany, OR, helps researchers investigate materials that can withstand the heat and pressure commonly found in fossil energy...

  9. Philadelphia District Laboratory (PHI)

    Data.gov (United States)

    Federal Laboratory Consortium — Program Capabilities PHI-DO Pharmaceutical Laboratory specializes in the analyses of all forms and types of drug products.Its work involves nearly all phases of drug...

  10. Geometric Design Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The mission of the Geometric Design Laboratory (GDL) is to support the Office of Safety Research and Development in research related to the geometric design...

  11. Space Systems Laboratory (SSL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Space Systems Laboratory (SSL) is part of the Aerospace Engineering Department and A. James Clark School of Engineering at the University of Maryland in College...

  12. Detroit District Laboratory (DET)

    Data.gov (United States)

    Federal Laboratory Consortium — Program CapabilitiesDET-DO Laboratory is equipped with the usual instrumentation necessary to perform a wide range of analyses of food, drugs and cosmetics. Program...

  13. Clinical Laboratory Fee Schedule

    Data.gov (United States)

    U.S. Department of Health & Human Services — Outpatient clinical laboratory services are paid based on a fee schedule in accordance with Section 1833(h) of the Social Security Act. The clinical laboratory fee...

  14. Aircraft Fire Protection Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Navy Aircraft Protection Laboratory provides complete test support for all Navy air vehicle fire protection systems.The facility allows for the simulation of a...

  15. Radiochemical Processing Laboratory (RPL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Radiochemical Processing Laboratory (RPL)�is a scientific facility funded by DOE to create and implement innovative processes for environmental clean-up and...

  16. Detroit District Laboratory (DET)

    Data.gov (United States)

    Federal Laboratory Consortium — Program Capabilities DET-DO Laboratory is equipped with the usual instrumentation necessary to perform a wide range of analyses of food, drugs and cosmetics. Program...

  17. High Bay Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory is a specially constructed facility with elevated (37 feet) ceilings and an overhead catwalk, and which is dedicated to research efforts in reducing...

  18. Laboratory Demographics Lookup Tool

    Data.gov (United States)

    U.S. Department of Health & Human Services — This website provides demographic information about laboratories, including CLIA number, facility name and address, where the laboratory testing is performed, the...

  19. Human Factors Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The purpose of the Human Factors Laboratory is to further the understanding of highway user needs so that those needs can be incorporated in roadway design,...

  20. Geological Services Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Researchers use computed tomography (CT) scanners at NETL’s Geological Services Laboratory in Morgantown, WV, to peer into geologic core samples to determine how...

  1. Philadelphia District Laboratory (PHI)

    Data.gov (United States)

    Federal Laboratory Consortium — Program CapabilitiesPHI-DO Pharmaceutical Laboratory specializes in the analyses of all forms and types of drug products.Its work involves nearly all phases of drug...

  2. Protective Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory is a 40 by 28 by 9 foot facility that is equipped with tools for the development of various items of control technology related to the transmission...

  3. Neutral Buoyancy Laboratory (NBL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Neutral Buoyancy Laboratory (NBL) is an astronaut training facility and neutral buoyancy pool operated by NASA and located at the Sonny Carter Training Facility,...

  4. Aircraft Fire Protection Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Navy Aircraft Protection Laboratory provides complete test support for all Navy air vehicle fire protection systems. The facility allows for the simulation of a...

  5. Energetics Laboratory Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — These energetic materials laboratories are equipped with explosion proof hoods with blow out walls for added safety, that are certified for safe handling of primary...

  6. Moriah Wind System Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The Moriah Wind System Laboratory provides in-service support for the more than 50 U.S. Navy, U.S. Coast Guard and Military Sealift Command ships on which...

  7. Toxicologic evaluation of analytes from Tank 241-C-103

    Energy Technology Data Exchange (ETDEWEB)

    Mahlum, D.D.; Young, J.Y.; Weller, R.E.

    1994-11-01

    Westinghouse Hanford Company requested PNL to assemble a toxicology review panel (TRP) to evaluate analytical data compiled by WHC, and provide advice concerning potential health effects associated with exposure to tank-vapor constituents. The team`s objectives would be to (1) review procedures used for sampling vapors from tanks, (2) identify constituents in tank-vapor samples that could be related to symptoms reported by workers, (3) evaluate the toxicological implications of those constituents by comparison to establish toxicological databases, (4) provide advice for additional analytical efforts, and (5) support other activities as requested by WHC. The TRP represents a wide range of expertise, including toxicology, industrial hygiene, and occupational medicine. The TRP prepared a list of target analytes that chemists at the Oregon Graduate Institute/Sandia (OGI), Oak Ridge National Laboratory (ORNL), and PNL used to establish validated methods for quantitative analysis of head-space vapors from Tank 241-C-103. this list was used by the analytical laboratories to develop appropriate analytical methods for samples from Tank 241-C-103. Target compounds on the list included acetone, acetonitrile, ammonia, benzene, 1, 3-butadiene, butanal, n-butanol, hexane, 2-hexanone, methylene chloride, nitric oxide, nitrogen dioxide, nitrous oxide, dodecane, tridecane, propane nitrile, sulfur oxide, tributyl phosphate, and vinylidene chloride. The TRP considered constituent concentrations, current exposure limits, reliability of data relative to toxicity, consistency of the analytical data, and whether the material was carcinogenic or teratogenic. A final consideration in the analyte selection process was to include representative chemicals for each class of compounds found.

  8. Second International Workshop on Teaching Analytics

    DEFF Research Database (Denmark)

    Vatrapu, Ravi; Reimann, Peter; Halb, Wolfgang;

    2013-01-01

    Teaching Analytics is conceived as a subfield of learning analytics that focuses on the design, development, evaluation, and education of visual analytics methods and tools for teachers in primary, secondary, and tertiary educational settings. The Second International Workshop on Teaching Analytics...... (IWTA) 2013 seeks to bring together researchers and practitioners in the fields of education, learning sciences, learning analytics, and visual analytics to investigate the design, development, use, evaluation, and impact of visual analytical methods and tools for teachers’ dynamic diagnostic decision...

  9. Nuclear Reactor Engineering Analysis Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Carlos Chavez-Mercado; Jaime B. Morales-Sandoval; Benjamin E. Zayas-Perez

    1998-12-31

    The Nuclear Reactor Engineering Analysis Laboratory (NREAL) is a sophisticated computer system with state-of-the-art analytical tools and technology for analysis of light water reactors. Multiple application software tools can be activated to carry out different analyses and studies such as nuclear fuel reload evaluation, safety operation margin measurement, transient and severe accident analysis, nuclear reactor instability, operator training, normal and emergency procedures optimization, and human factors engineering studies. An advanced graphic interface, driven through touch-sensitive screens, provides the means to interact with specialized software and nuclear codes. The interface allows the visualization and control of all observable variables in a nuclear power plant (NPP), as well as a selected set of nonobservable or not directly controllable variables from conventional control panels.

  10. Nuclear techniques in analytical chemistry

    CERN Document Server

    Moses, Alfred J; Gordon, L

    1964-01-01

    Nuclear Techniques in Analytical Chemistry discusses highly sensitive nuclear techniques that determine the micro- and macro-amounts or trace elements of materials. With the increasingly frequent demand for the chemical determination of trace amounts of elements in materials, the analytical chemist had to search for more sensitive methods of analysis. This book accustoms analytical chemists with nuclear techniques that possess the desired sensitivity and applicability at trace levels. The topics covered include safe handling of radioactivity; measurement of natural radioactivity; and neutron a

  11. Banach spaces of analytic functions

    CERN Document Server

    Hoffman, Kenneth

    2007-01-01

    A classic of pure mathematics, this advanced graduate-level text explores the intersection of functional analysis and analytic function theory. Close in spirit to abstract harmonic analysis, it is confined to Banach spaces of analytic functions in the unit disc.The author devotes the first four chapters to proofs of classical theorems on boundary values and boundary integral representations of analytic functions in the unit disc, including generalizations to Dirichlet algebras. The fifth chapter contains the factorization theory of Hp functions, a discussion of some partial extensions of the f

  12. Methodological and analytic considerations for blood biomarkers.

    Science.gov (United States)

    Christenson, Robert H; Duh, Show-Hong

    2012-01-01

    Biomarkers typically evolve from a research setting to use in clinical care as evidence for their independent contribution to patient management accumulates. This evidence relies heavily on knowledge of the preanalytical, analytical, and postanalytical characteristics of the biomarker's measurement. For the preanalytical phase, considerations such specimen type, acceptable anticoagulants for blood samples, biologic variation and stability of the biomarker under various conditions are key. The analytical phase entails critical details for development and maintenance of assays having performance characteristics that are "fit for service" for the clinical application at hand. Often, these characteristics describe the ability to measure minute quantities in the biologic matrix used for measurement. Although techniques such as mass spectrometry are used effectively for biomarker discovery, routine quantification often relies on use of immunoassays; early in development, the most common immunoassay used is the enzyme-linked immunosorbent assay format. As biomarkers evolve successfully, they will be adapted to large main laboratory platforms or, depending on the need for speed, point-of-care devices. Users must pay particular attention to performance parameters of assays they are considering for clinical implementation. These parameters include the limit of blank, a term used to describe the limit of analytical noise for an assay; limit of detection, which describes the lowest concentration that can reliably be discriminated from analytical noise; and perhaps most importantly, the limit of quantitation, which is the lowest concentration at which a biomarker can be reliably measured within some predefined specifications for total analytical error that is based on clinical requirements of the test. The postanalytical phase involves reporting biomarker values, which includes reporting units, any normalization factors, and interpretation. Standardization, a process that

  13. Informatics and the clinical laboratory.

    Science.gov (United States)

    Jones, Richard G; Johnson, Owen A; Batstone, Gifford

    2014-08-01

    The nature of pathology services is changing under the combined pressures of increasing workloads, cost constraints and technological advancement. In the face of this, laboratory systems need to meet new demands for data exchange with clinical electronic record systems for test requesting and results reporting. As these needs develop, new challenges are emerging especially with respect to the format and content of the datasets which are being exchanged. If the potential for the inclusion of intelligent systems in both these areas is to be realised, the continued dialogue between clinicians and laboratory information specialists is of paramount importance. Requirements of information technology (IT) in pathology, now extend well beyond the provision of purely analytical data. With the aim of achieving seamless integration of laboratory data into the total clinical pathway, 'Informatics' - the art and science of turning data into useful information - is becoming increasingly important in laboratory medicine. Informatics is a powerful tool in pathology - whether in implementing processes for pathology modernisation, introducing new diagnostic modalities (e.g. proteomics, genomics), providing timely and evidence-based disease management, or enabling best use of limited and often costly resources. Providing appropriate information to empowered and interested patients - which requires critical assessment of the ever-increasing volume of information available - can also benefit greatly from appropriate use of informatics in enhancing self-management of long term conditions. The increasing demands placed on pathology information systems in the context of wider developmental change in healthcare delivery are explored in this review. General trends in medical informatics are reflected in current priorities for laboratory medicine, including the need for unified electronic records, computerised order entry, data security and recovery, and audit. We conclude that there is a

  14. Nuclear analytical techniques in environmental studies.

    Science.gov (United States)

    Jervis, R E

    1994-01-01

    Nuclear analytical techniques are particularly suitable for measuring trace components in a wide variety of environmental samples, and for that reason, the techniques have made a significant contribution to environmental research. Presently, at a time when biosphere contamination and threats of global change in the atmosphere are of widespread concern, there exist an impressive array of specialized instrumental methods available to life scientists engaged in environmental studies; however, the nuclear techniques will probably continue to play a useful role in the future, notwithstanding the decreasing availability of necessary facilities, such as research reactors and accelerators. Reasons for the particular suitability of radionanalytical techniques are reviewed and illustrated by examples of recent applications to solid wastes, biomonitoring, and urban aerosol source identification in this laboratory.

  15. Characterizing the Laboratory Market

    Energy Technology Data Exchange (ETDEWEB)

    Shehabi, Arman; Ganeshalingam, Mohan; DeMates, Lauren; Mathew, Paul; Sartor, Dale

    2017-04-11

    Laboratories are estimated to be 3-5 times more energy intensive than typical office buildings and offer significant opportunities for energy use reductions. Although energy intensity varies widely, laboratories are generally energy intensive due to ventilation requirements, the research instruments used, and other health and safety concerns. Because the requirements of laboratory facilities differ so dramatically from those of other buildings, a clear need exists for an initiative exclusively targeting these facilities. The building stock of laboratories in the United States span different economic sectors, include governmental and academic institution, and are often defined differently by different groups. Information on laboratory buildings is often limited to a small subsection of the total building stock making aggregate estimates of the total U.S. laboratories and their energy use challenging. Previous estimates of U.S. laboratory space vary widely owing to differences in how laboratories are defined and categorized. A 2006 report on fume hoods provided an estimate of 150,000 laboratories populating the U.S. based in part on interviews of industry experts, however, a 2009 analysis of the 2003 Commercial Buildings Energy Consumption Survey (CBECS) generated an estimate of only 9,000 laboratory buildings. This report draws on multiple data sources that have been evaluated to construct an understanding of U.S. laboratories across different sizes and markets segments. This 2016 analysis is an update to draft reports released in October and December 2016.

  16. Waste Tank Organic Safety Program: Analytical methods development. Progress report, FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, J.A.; Clauss, S.A.; Grant, K.E. [and others

    1994-09-01

    The objectives of this task are to develop and document extraction and analysis methods for organics in waste tanks, and to extend these methods to the analysis of actual core samples to support the Waste Tank organic Safety Program. This report documents progress at Pacific Northwest Laboratory (a) during FY 1994 on methods development, the analysis of waste from Tank 241-C-103 (Tank C-103) and T-111, and the transfer of documented, developed analytical methods to personnel in the Analytical Chemistry Laboratory (ACL) and 222-S laboratory. This report is intended as an annual report, not a completed work.

  17. Personalized laboratory medicine

    DEFF Research Database (Denmark)

    Pazzagli, M.; Malentacchi, F.; Mancini, I.

    2015-01-01

    Developments in "omics" are creating a paradigm shift in Laboratory Medicine leading to Personalised Medicine. This allows the increasing in diagnostics and therapeutics focused on individuals rather than populations. In order to investigate whether Laboratory Medicine is able to implement new...... diagnostic tools and expertise and commands proper state-of-the-art knowledge about Personalized Medicine and Laboratory Medicine in Europe, the joint Working Group "Personalized Laboratory Medicine" of the EFLM and ESPT societies compiled and conducted the Questionnaire "Is Laboratory Medicine ready...... for the era of Personalized Medicine?". 48 laboratories from 18 European countries participated at this survey. The answers of the participating Laboratory Medicine professionals indicate that they are aware that Personalized Medicine can represent a new and promising health model. Whereas they are aware...

  18. Analytic Methods in Investigative Geometry.

    Science.gov (United States)

    Dobbs, David E.

    2001-01-01

    Suggests an alternative proof by analytic methods, which is more accessible than rigorous proof based on Euclid's Elements, in which students need only apply standard methods of trigonometry to the data without introducing new points or lines. (KHR)

  19. Labour Market Driven Learning Analytics

    Science.gov (United States)

    Kobayashi, Vladimer; Mol, Stefan T.; Kismihók, Gábor

    2014-01-01

    This paper briefly outlines a project about integrating labour market information in a learning analytics goal-setting application that provides guidance to students in their transition from education to employment.

  20. Increasing Efficiency and Quality by Consolidation of Clinical Chemistry and Immunochemistry Systems with MODULAR ANALYTICS SWA.

    Science.gov (United States)

    Mocarelli, Paolo; Horowitz, Gary L; Gerthoux, Pier Mario; Cecere, Rossana; Imdahl, Roland; Ruinemans-Koerts, Janneke; Luthe, Hilmar; Calatayud, Silvia Pesudo; Salve, Marie Luisa; Kunst, Albert; McGovern, Margaret; Ng, Katherine; Stockmann, Wolfgang

    2008-01-01

    MODULAR ANALYTICS Serum Work Area (in USA Integrated MODULAR ANALYTICS, MODULAR ANALYTICS is a trademark of a member of the Roche Group) represents a further approach to automation in the laboratory medicine. This instrument combines previously introduced modular systems for the clinical chemistry and immunochemistry laboratory and allows customised combinations for various laboratory workloads. Functionality, practicability, and workflow behaviour of MODULAR ANALYTICS Serum Work Area were evaluated in an international multicenter study at six laboratories. Across all experiments, 236000 results from 32400 samples were generated using 93 methods. Simulated routine testing which included provocation incidents and anomalous situations demonstrated good performance and full functionality. Heterogeneous immunoassays, performed on the E-module with the electrochemiluminescence technology, showed reproducibility at the same level of the general chemistry tests, which was well within the clinical demands. Sample carryover cannot occur due to intelligent sample processing. Workflow experiments for the various module combinations, with menus of about 50 assays, yielded mean sample processing times of chemistry and immunochemistry requests; ANALYTICS Serum Work Area offered simplified workflow by combining various laboratory segments. It increased efficiency while maintaining or even improving quality of laboratory processes.

  1. Analytical methods used to measure acrylamide concentrations in foods.

    Science.gov (United States)

    Castle, Laurence; Eriksson, Sune

    2005-01-01

    The state-of-the-art of analysis for acrylamide in food is reviewed. The majority of analytical methods adopts a similar approach: addition of internal standard to the specimen, extraction with water, purification of extract using a solid-phase extraction cartridge, and then determination using either gas chromatography coupled to mass spectroscopy (GC/MS) after bromination, or direct measurement with liquid chromatography coupled to mass spectroscopy (LC/MS). The available methods generally show good agreement and are likely to be accurate. However, improvements in precision (within-laboratory) and repeatability (between-laboratory) are needed by particular data users.

  2. Winchester Engineering Analytical Center (WEAC)

    Data.gov (United States)

    Federal Laboratory Consortium — rogram Capabilities WEAC performs analyses in support of the Medical Device Program Area and radionuclide chemical as well as microbiological analyses for the Food...

  3. Analytical balance-based Faraday magnetometer

    Science.gov (United States)

    Riminucci, Alberto; Uhlarz, Marc; De Santis, Roberto; Herrmannsdörfer, Thomas

    2017-03-01

    We introduce a Faraday magnetometer based on an analytical balance in which we were able to apply magnetic fields up to 0.14 T. We calibrated it with a 1 mm Ni sphere previously characterized in a superconducting quantum interference device (SQUID) magnetometer. The proposed magnetometer reached a theoretical sensitivity of 3 × 10-8 A m2. We demonstrated its operation on magnetic composite scaffolds made of poly(ɛ-caprolactone)/iron-doped hydroxyapatite. To confirm the validity of the method, we measured the same scaffold properties in a SQUID magnetometer. The agreement between the two measurements was within 5% at 0.127 T and 12% at 24 mT. With the addition, for a small cost, of a permanent magnet and computer controlled linear translators, we were thus able to assemble a Faraday magnetometer based on an analytical balance, which is a virtually ubiquitous instrument. This will make simple but effective magnetometry easily accessible to most laboratories, in particular, to life sciences ones, which are increasingly interested in magnetic materials.

  4. Analytical models for complex swirling flows

    Science.gov (United States)

    Borissov, A.; Hussain, V.

    1996-11-01

    We develops a new class of analytical solutions of the Navier-Stokes equations for swirling flows, and suggests ways to predict and control such flows occurring in various technological applications. We view momentum accumulation on the axis as a key feature of swirling flows and consider vortex-sink flows on curved axisymmetric surfaces with an axial flow. We show that these solutions model swirling flows in a cylindrical can, whirlpools, tornadoes, and cosmic swirling jets. The singularity of these solutions on the flow axis is removed by matching them with near-axis Schlichting and Long's swirling jets. The matched solutions model flows with very complex patterns, consisting of up to seven separation regions with recirculatory 'bubbles' and vortex rings. We apply the matched solutions for computing flows in the Ranque-Hilsch tube, in the meniscus of electrosprays, in vortex breakdown, and in an industrial vortex burner. The simple analytical solutions allow a clear understanding of how different control parameters affect the flow and guide selection of optimal parameter values for desired flow features. These solutions permit extension to other problems (such as heat transfer and chemical reaction) and have the potential of being significantly useful for further detailed investigation by direct or large-eddy numerical simulations as well as laboratory experimentation.

  5. Functionalized magnetic nanoparticle analyte sensor

    Science.gov (United States)

    Yantasee, Wassana; Warner, Maryin G; Warner, Cynthia L; Addleman, Raymond S; Fryxell, Glen E; Timchalk, Charles; Toloczko, Mychailo B

    2014-03-25

    A method and system for simply and efficiently determining quantities of a preselected material in a particular solution by the placement of at least one superparamagnetic nanoparticle having a specified functionalized organic material connected thereto into a particular sample solution, wherein preselected analytes attach to the functionalized organic groups, these superparamagnetic nanoparticles are then collected at a collection site and analyzed for the presence of a particular analyte.

  6. Analytic torsion and symplectic volume

    DEFF Research Database (Denmark)

    McLellan, Brendan Donald Kenneth

    2013-01-01

    This article studies the abelian analytic torsion on a closed, oriented, quasi-regular Sasakian three-manifold and identifies this quantity as a specific multiple of the natural unit symplectic volume form on the moduli space of flat abelian connections. This identification effectively computes...... the analytic torsion explicitly in terms of Seifert data for a given quasi-regular Sasakian structure on a three-manifold....

  7. Organizational Models for Big Data and Analytics

    Directory of Open Access Journals (Sweden)

    Robert L. Grossman

    2014-04-01

    Full Text Available In this article, we introduce a framework for determining how analytics capability should be distributed within an organization. Our framework stresses the importance of building a critical mass of analytics staff, centralizing or decentralizing the analytics staff to support business processes, and establishing an analytics governance structure to ensure that analytics processes are supported by the organization as a whole.

  8. Organizational Models for Big Data and Analytics

    OpenAIRE

    Grossman, Robert L.; Kevin P. Siegel

    2014-01-01

    In this article, we introduce a framework for determining how analytics capability should be distributed within an organization. Our framework stresses the importance of building a critical mass of analytics staff, centralizing or decentralizing the analytics staff to support business processes, and establishing an analytics governance structure to ensure that analytics processes are supported by the organization as a whole.

  9. Mining of hospital laboratory information systems

    DEFF Research Database (Denmark)

    Søeby, Karen; Jensen, Peter Bjødstrup; Werge, Thomas

    2015-01-01

    of hospital laboratory data as a source of information, we analyzed enzymatic plasma creatinine as a model analyte in two large pediatric hospital samples. Methods: Plasma creatinine measurements from 9700 children aged 0-18 years were obtained from hospital laboratory databases and partitioned into high......-resolution gender- and age-groups. Normal probability plots were used to deduce parameters of the normal distributions from healthy creatinine values in the mixed hospital datasets. Furthermore, temporal trajectories were generated from repeated measurements to examine developmental patterns in periods of changing...... in creatinine levels at different time points after birth and around the early teens, which challenges the establishment and usefulness of reference intervals in those age groups. Conclusions: The study documents that hospital laboratory data may inform on the developmental aspects of creatinine, on periods...

  10. Synergistic relationships between Analytical Chemistry and written standards

    Energy Technology Data Exchange (ETDEWEB)

    Valcárcel, Miguel, E-mail: qa1vacam@uco.es; Lucena, Rafael

    2013-07-25

    Graphical abstract: -- Highlights: •Analytical Chemistry is influenced by international written standards. •Different relationships can be established between them. •Synergies can be generated when these standards are conveniently managed. -- Abstract: This paper describes the mutual impact of Analytical Chemistry and several international written standards (norms and guides) related to knowledge management (CEN-CWA 14924:2004), social responsibility (ISO 26000:2010), management of occupational health and safety (OHSAS 18001/2), environmental management (ISO 14001:2004), quality management systems (ISO 9001:2008) and requirements of the competence of testing and calibration laboratories (ISO 17025:2004). The intensity of this impact, based on a two-way influence, is quite different depending on the standard considered. In any case, a new and fruitful approach to Analytical Chemistry based on these relationships can be derived.

  11. Green Chemistry Metrics with Special Reference to Green Analytical Chemistry

    OpenAIRE

    Marek Tobiszewski; Mariusz Marć; Agnieszka Gałuszka; Jacek Namieśnik

    2015-01-01

    The concept of green chemistry is widely recognized in chemical laboratories. To properly measure an environmental impact of chemical processes, dedicated assessment tools are required. This paper summarizes the current state of knowledge in the field of development of green chemistry and green analytical chemistry metrics. The diverse methods used for evaluation of the greenness of organic synthesis, such as eco-footprint, E-Factor, EATOS, and Eco-Scale are described. Both the well-establis...

  12. Optics/Optical Diagnostics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Optics/Optical Diagnostics Laboratory supports graduate instruction in optics, optical and laser diagnostics and electro-optics. The optics laboratory provides...

  13. Heat Flux Instrumentation Laboratory (HFIL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Heat Flux Instrumentation Laboratory is used to develop advanced, flexible, thin film gauge instrumentation for the Air Force Research Laboratory....

  14. The detection and prevention of errors in laboratory medicine.

    Science.gov (United States)

    Plebani, Mario

    2010-03-01

    The last few decades have seen a significant decrease in the rates of analytical errors in clinical laboratories. Evidence demonstrates that pre- and post-analytical steps of the total testing process (TTP) are more error-prone than the analytical phase. Most errors are identified in pre-pre-analytic and post-post-analytic steps outside of the laboratory. In a patient-centred approach to the delivery of health-care services, there is the need to investigate, in the TTP, any possible defect that may have a negative impact on the patient. In the interests of patients, any direct or indirect negative consequence related to a laboratory test must be considered, irrespective of which step is involved and whether the error depends on a laboratory professional (e.g. calibration/testing error) or non-laboratory operator (e.g. inappropriate test request, error in patient identification and/or blood collection). Patient misidentification and problems communicating results, which affect the delivery of diagnostic services, are recognized as the main goals for quality improvement. International initiatives aim at improving these aspects. Grading laboratory errors on the basis of their seriousness should help identify priorities for quality improvement and encourage a focus on corrective/preventive actions. It is important to consider not only the actual patient harm sustained but also the potential worst-case outcome if such an error were to reoccur. The most important lessons we have learned are that system theory also applies to laboratory testing and that errors and injuries can be prevented by redesigning systems that render it difficult for all health-care professionals to make mistakes.

  15. Exploring the iceberg of errors in laboratory medicine.

    Science.gov (United States)

    Plebani, Mario

    2009-06-01

    The last few decades have seen a significant decrease in the rates of analytical errors in clinical laboratories, and currently available evidence demonstrates that the pre- and post-analytical steps of the total testing process (TTP) are more error-prone than the analytical phase. In particular, most errors are identified in pre-pre-analytic and post-post analytic steps outside the walls of the laboratory, and beyond its control. However, in a patient-centered approach to the delivery of health care services, there is the need to investigate any possible defect in the total testing process that may have a negative impact on the patient. In fact, in the interests of patients, any direct or indirect negative consequence related to a laboratory test must be considered, irrespective of which step is involved and whether the error is caused by a laboratory professional (e.g., calibration or testing error) or by a non-laboratory operator (e.g., inappropriate test request, error in patient identification and/or blood collection). Data on diagnostic errors in primary care and in the emergency department setting demonstrate that inappropriate test requesting and incorrect interpretation account for a large percentage of total errors whatever the discipline involved, be it radiology, pathology or laboratory medicine. Patient misidentification and problems in communicating results, which affect the delivery of all diagnostic services, are widely recognized as the main goals for quality improvement. Therefore, some common problems affect diagnostic errors, although specific faults characterising errors in laboratory medicine should lead to preventive and corrective actions if evidence-based quality indicators are developed, implemented and monitored. The lesson we have learned is that each practice must examine its own total testing process to discover its weaknesses and identify appropriate remedies.

  16. 75 FR 32950 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-06-10

    ... Incorporated; LabOne, Inc.; Center for Laboratory Services, a Division of LabOne, Inc.) Maxxam Analytics,* 6740 Campobello Road, Mississauga, ON, Canada L5N 2L8. 905-817-5700. (Formerly: Maxxam Analytics Inc., NOVAMANN... Laboratory, University of Missouri Hospital & Clinics, 301 Business Loop 70 West, Suite 208, Columbia,...

  17. How to assess the quality of your analytical method?

    Science.gov (United States)

    Topic, Elizabeta; Nikolac, Nora; Panteghini, Mauro; Theodorsson, Elvar; Salvagno, Gian Luca; Miler, Marijana; Simundic, Ana-Maria; Infusino, Ilenia; Nordin, Gunnar; Westgard, Sten

    2015-10-01

    Laboratory medicine is amongst the fastest growing fields in medicine, crucial in diagnosis, support of prevention and in the monitoring of disease for individual patients and for the evaluation of treatment for populations of patients. Therefore, high quality and safety in laboratory testing has a prominent role in high-quality healthcare. Applied knowledge and competencies of professionals in laboratory medicine increases the clinical value of laboratory results by decreasing laboratory errors, increasing appropriate utilization of tests, and increasing cost effectiveness. This collective paper provides insights into how to validate the laboratory assays and assess the quality of methods. It is a synopsis of the lectures at the 15th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Continuing Postgraduate Course in Clinical Chemistry and Laboratory Medicine entitled "How to assess the quality of your method?" (Zagreb, Croatia, 24-25 October 2015). The leading topics to be discussed include who, what and when to do in validation/verification of methods, verification of imprecision and bias, verification of reference intervals, verification of qualitative test procedures, verification of blood collection systems, comparability of results among methods and analytical systems, limit of detection, limit of quantification and limit of decision, how to assess the measurement uncertainty, the optimal use of Internal Quality Control and External Quality Assessment data, Six Sigma metrics, performance specifications, as well as biological variation. This article, which continues the annual tradition of collective papers from the EFLM continuing postgraduate courses in clinical chemistry and laboratory medicine, aims to provide further contributions by discussing the quality of laboratory methods and measurements and, at the same time, to offer continuing professional development to the attendees.

  18. Biochemical Technology Program progress report for the period January 1--June 30, 1976. [Centrifugal analyzers and advanced analytical systems for blood and body fluids

    Energy Technology Data Exchange (ETDEWEB)

    Mrochek, J.E.; Burtis, C.A.; Scott, C.D. (comps.)

    1976-09-01

    This document, which covers the period January 1-June 30, 1976, describes progress in the following areas: (1) advanced analytical techniques for the clinical laboratory, (2) fast clinical analyzers, (3) development of a miniaturized analytical clinical laboratory system, (4) centrifugal fast analyzers for animal toxicological studies, and (5) chemical profile of body fluids.

  19. Behavioral Neuroscience Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This lab supports cognitive research using rodent models. Capabilities for behavioral assessments include: Morris water maze and Barnes maze (spatial memory) elevate...

  20. Free Surface Hydrodynamics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Investigates processes and interactions at the air-sea interface, and compares measurements to numerical simulations and field data. Typical phenomena of...

  1. Laboratory for Structural Acoustics

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports experimental research where acoustic radiation, scattering, and surface vibration measurements of fluid-loaded and non-fluid-loaded structures are...

  2. Biochemical Neuroscience Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This biochemistry lab is set up for protein analysis using Western blot, enzyme linked immunosorbent assays, immunohistochemistry, and bead-based immunoassays. The...

  3. Metallurgical Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to increase basic knowledge of metallurgical processing for controlling the microstructure and mechanical properties of metallic aerospace alloys and...

  4. Head Impact Laboratory (HIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The HIL uses testing devices to evaluate vehicle interior energy attenuating (EA) technologies for mitigating head injuries resulting from head impacts during mine/...

  5. Flying Electronic Warfare Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides NP-3D aircraft host platforms for Effectiveness of Navy Electronic Warfare Systems (ENEWS) Program antiship missile (ASM) seeker simulators used...

  6. Shallow Water Acoustic Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports experimental research where high-frequency acoustic scattering and surface vibration measurements of fluid-loaded and non-fluid-loaded structures...

  7. Materials Behavior Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to evaluate mechanical properties of materials including metals, intermetallics, metal-matrix composites, and ceramic-matrix composites under typical...

  8. Structural Dynamics Laboratory (SDL)

    Data.gov (United States)

    Federal Laboratory Consortium — Structural dynamic testing is performed to verify the survivability of a component or assembly when exposed to vibration stress screening, or a controlled simulation...

  9. Applied Neuroscience Laboratory Complex

    Data.gov (United States)

    Federal Laboratory Consortium — Located at WPAFB, Ohio, the Applied Neuroscience lab researches and develops technologies to optimize Airmen individual and team performance across all AF domains....

  10. Sediment Core Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation and expertise for physical and geoacoustic characterization of marine sediments.DESCRIPTION: The multisensor core logger measures...

  11. GSPEL - Air Filtration Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Evaluation capabilities for air filtration devices The Air Filtration Lab provides testing of air filtration devices to demonstrate and validate new or legacy system...

  12. Sediment Core Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation and expertise for physical and geoacoustic characterization of marine sediments. DESCRIPTION: The multisensor core logger measures...

  13. High Temperature Materials Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The High Temperature Materials Lab provides the Navy and industry with affordable high temperature materials for advanced propulsion systems. Asset List: Arc Melter...

  14. Behavioral Neuroscience Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This lab supports cognitive research using rodent models. Capabilities for behavioral assessments include:Morris water maze and Barnes maze (spatial memory)elevate...

  15. Climate Analytics as a Service

    Science.gov (United States)

    Schnase, John L.; Duffy, Daniel Q.; McInerney, Mark A.; Webster, W. Phillip; Lee, Tsengdar J.

    2014-01-01

    Climate science is a big data domain that is experiencing unprecedented growth. In our efforts to address the big data challenges of climate science, we are moving toward a notion of Climate Analytics-as-a-Service (CAaaS). CAaaS combines high-performance computing and data-proximal analytics with scalable data management, cloud computing virtualization, the notion of adaptive analytics, and a domain-harmonized API to improve the accessibility and usability of large collections of climate data. MERRA Analytic Services (MERRA/AS) provides an example of CAaaS. MERRA/AS enables MapReduce analytics over NASA's Modern-Era Retrospective Analysis for Research and Applications (MERRA) data collection. The MERRA reanalysis integrates observational data with numerical models to produce a global temporally and spatially consistent synthesis of key climate variables. The effectiveness of MERRA/AS has been demonstrated in several applications. In our experience, CAaaS is providing the agility required to meet our customers' increasing and changing data management and data analysis needs.

  16. Analytical results for the 107-N and 1310-N basin sedimentdisposition sample characterization project

    Energy Technology Data Exchange (ETDEWEB)

    Miller, G.L.

    1997-06-02

    Turnaround time for this project was 60 days, as required in Reference 2. The analyses were to be performed using SW-846 procedures whenever possible to meet analytical requirements as a Resource Conservation Recovery Act (RCRA) protocol project. Except for the preparation and analyses of polychlorinated biphenyl hydrocarbons (PCB) and Nickel-63, which the program deleted as a required analyte for 222-S Laboratory, all preparative and analytical work was performed at the 222-S Laboratory. Quanterra Environmental Services of Earth City, Missouri, performed the PCB analyses. During work on this project, two events occurred nearly simultaneously, which negatively impacted the 60 day deliverable schedule: an analytical hold due to waste handling issues at the 222-S Laboratory, and the discovery of PCBs at concentrations of regulatory significance in the 105-N Basin samples. Due to findings of regulatory non-compliance by the Washington State, Department of Ecology, the 222-S Laboratory placed a temporary administrative hold on its analytical work until all waste handling, designation and segregation issues were resolved. During the hold of approximately three weeks, all analytical and waste.handling procedures were rewritten to comply with the legal regulations, and all staff were retrained in the designation, segregation and disposal of RCRA liquid and solid wastes.

  17. Analytical approximations for spiral waves

    Energy Technology Data Exchange (ETDEWEB)

    Löber, Jakob, E-mail: jakob@physik.tu-berlin.de; Engel, Harald [Institut für Theoretische Physik, Technische Universität Berlin, Hardenbergstrasse 36, EW 7-1, 10623 Berlin (Germany)

    2013-12-15

    We propose a non-perturbative attempt to solve the kinematic equations for spiral waves in excitable media. From the eikonal equation for the wave front we derive an implicit analytical relation between rotation frequency Ω and core radius R{sub 0}. For free, rigidly rotating spiral waves our analytical prediction is in good agreement with numerical solutions of the linear eikonal equation not only for very large but also for intermediate and small values of the core radius. An equivalent Ω(R{sub +}) dependence improves the result by Keener and Tyson for spiral waves pinned to a circular defect of radius R{sub +} with Neumann boundaries at the periphery. Simultaneously, analytical approximations for the shape of free and pinned spirals are given. We discuss the reasons why the ansatz fails to correctly describe the dependence of the rotation frequency on the excitability of the medium.

  18. Spatial Game Analytics and Visualization

    DEFF Research Database (Denmark)

    Drachen, Anders; Schubert, Matthias

    2013-01-01

    The recently emerged field of game analytics and the development and adaptation of business intelligence techniques to support game design and development has given data-driven techniques a direct role in game development. Given that all digital games contain some sort of spatial operation...... for a continuing development. This paper presents a review of current work on spatial and spatio-temporal game analytics across industry and research, describing and defining the key terminology, outlining current techniques and their application. We summarize the current problems and challenges in the field......, and present four key areas of spatial and spatio-temporal analytics: Spatial Outlier Detection, Spatial Clustering, Spatial Predictive Models, Spatial Pattern and Rule Mining. All key areas are well-established outside the context of games and hold the potential to reshape the research roadmap in game...

  19. Strongly nonlinear oscillators analytical solutions

    CERN Document Server

    Cveticanin, Livija

    2014-01-01

    This book provides the presentation of the motion of pure nonlinear oscillatory systems and various solution procedures which give the approximate solutions of the strong nonlinear oscillator equations. The book presents the original author’s method for the analytical solution procedure of the pure nonlinear oscillator system. After an introduction, the physical explanation of the pure nonlinearity and of the pure nonlinear oscillator is given. The analytical solution for free and forced vibrations of the one-degree-of-freedom strong nonlinear system with constant and time variable parameter is considered. Special attention is given to the one and two mass oscillatory systems with two-degrees-of-freedom. The criteria for the deterministic chaos in ideal and non-ideal pure nonlinear oscillators are derived analytically. The method for suppressing chaos is developed. Important problems are discussed in didactic exercises. The book is self-consistent and suitable as a textbook for students and also for profess...

  20. Streamlining Smart Meter Data Analytics

    DEFF Research Database (Denmark)

    Liu, Xiufeng; Nielsen, Per Sieverts

    2015-01-01

    with the complexity of data processing and data analytics. The system offers an information integration pipeline to ingest smart meter data; scalable data processing and analytic platform for pre-processing and mining big smart meter data sets; and a web-based portal for visualizing data analytics results. The system......Today smart meters are increasingly used in worldwide. Smart meters are the advanced meters capable of measuring customer energy consumption at a fine-grained time interval, e.g., every 15 minutes. The data are very sizable, and might be from different sources, along with the other social......-economic metrics such as the geographic information of meters, the information about users and their property, geographic location and others, which make the data management very complex. On the other hand, data-mining and the emerging cloud computing technologies make the collection, management, and analysis...

  1. Big Data Analytics in Healthcare.

    Science.gov (United States)

    Belle, Ashwin; Thiagarajan, Raghuram; Soroushmehr, S M Reza; Navidi, Fatemeh; Beard, Daniel A; Najarian, Kayvan

    2015-01-01

    The rapidly expanding field of big data analytics has started to play a pivotal role in the evolution of healthcare practices and research. It has provided tools to accumulate, manage, analyze, and assimilate large volumes of disparate, structured, and unstructured data produced by current healthcare systems. Big data analytics has been recently applied towards aiding the process of care delivery and disease exploration. However, the adoption rate and research development in this space is still hindered by some fundamental problems inherent within the big data paradigm. In this paper, we discuss some of these major challenges with a focus on three upcoming and promising areas of medical research: image, signal, and genomics based analytics. Recent research which targets utilization of large volumes of medical data while combining multimodal data from disparate sources is discussed. Potential areas of research within this field which have the ability to provide meaningful impact on healthcare delivery are also examined.

  2. Big Data Analytics in Healthcare

    Directory of Open Access Journals (Sweden)

    Ashwin Belle

    2015-01-01

    Full Text Available The rapidly expanding field of big data analytics has started to play a pivotal role in the evolution of healthcare practices and research. It has provided tools to accumulate, manage, analyze, and assimilate large volumes of disparate, structured, and unstructured data produced by current healthcare systems. Big data analytics has been recently applied towards aiding the process of care delivery and disease exploration. However, the adoption rate and research development in this space is still hindered by some fundamental problems inherent within the big data paradigm. In this paper, we discuss some of these major challenges with a focus on three upcoming and promising areas of medical research: image, signal, and genomics based analytics. Recent research which targets utilization of large volumes of medical data while combining multimodal data from disparate sources is discussed. Potential areas of research within this field which have the ability to provide meaningful impact on healthcare delivery are also examined.

  3. Nuclear Waste Analytical Round Robins 1-6 summary report

    Energy Technology Data Exchange (ETDEWEB)

    Smith, G.L.; Marschman, S.C.

    1993-12-31

    The MCC has conducted six round robins for the waste management, research, and development community from 1987 to present. The laboratories participating regularly are Ames, Argonne, Catholic University, Lawrence Livermore, Pacific Northwest Laboratory, Savannah River, and West Valley Nuclear. Glass types analyzed in these round robins all have been simulated nuclear waste compositions expected from vitrification of high-level nuclear waste. A wide range of analytical procedures have been used by the participating laboratories including Atomic Absorption spectroscopy, inductively coupled plasma-atomic emission spectroscopy, direct current plasma-emission spectroscopy, and inductively coupled plasma-mass spectroscopy techniques. Consensus average relative error for Round Robins 1 through 6 is 5.4%, with values ranging from 9.4 to 1.1%. Trend on the average improved with each round robin. When the laboratories analyzed samples over longer periods of time, the intralaboratory variability increased. Lab-to-lab variation accounts for most of the total variability found in all the round robins. Participation in the radiochemistry portion has been minimal, and analytical results poor compared to nonradiochemistry portion. Additional radiochemical work is needed in future round robins.

  4. Exact analytical solutions for ADAFs

    CERN Document Server

    Habibi, Asiyeh; Shadmehri, Mohsen

    2016-01-01

    We obtain two-dimensional exact analytic solutions for the structure of the hot accretion flows without wind. We assume that the only non-zero component of the stress tensor is $T_{r\\varphi}$. Furthermore we assume that the value of viscosity coefficient $\\alpha$ varies with $\\theta$. We find radially self-similar solutions and compare them with the numerical and the analytical solutions already studied in the literature. The no-wind solution obtained in this paper may be applied to the nuclei of some cool-core clusters.

  5. The Virtual Robotics Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Kress, R.L.; Love, L.J.

    1999-09-01

    The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory secondary education programs. In the past, the ORNL Robotics and Process Systems Division has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well as many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics. but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his/her students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations.

  6. The Virtual Robotics Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Kress, R.L. [Oak Ridge National Lab., TN (United States); Love, L.J. [Oak Ridge Inst. for Science and Education, TN (United States)

    1997-03-01

    The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory equipment to outside universities, industrial researchers, and elementary and secondary education programs. In the past, the ORNL Robotics and Process Systems Division (RPSD) has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well as many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics, but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations.

  7. NVLAP calibration laboratory program

    Energy Technology Data Exchange (ETDEWEB)

    Cigler, J.L.

    1993-12-31

    This paper presents an overview of the progress up to April 1993 in the development of the Calibration Laboratories Accreditation Program within the framework of the National Voluntary Laboratory Accreditation Program (NVLAP) at the National Institute of Standards and Technology (NIST).

  8. Quality in Teaching Laboratories.

    Science.gov (United States)

    Stubington, John F.

    1995-01-01

    Describes a Japanese process-oriented approach called KAIZEN for improving the quality of existing teaching laboratories. It provides relevant quality measurements and indicates how quality can be improved. Use of process criteria sidesteps the difficulty of defining quality for laboratory experiments and allows separation of student assessment…

  9. Analytical reasoning task reveals limits of social learning in networks.

    Science.gov (United States)

    Rahwan, Iyad; Krasnoshtan, Dmytro; Shariff, Azim; Bonnefon, Jean-François

    2014-04-06

    Social learning-by observing and copying others-is a highly successful cultural mechanism for adaptation, outperforming individual information acquisition and experience. Here, we investigate social learning in the context of the uniquely human capacity for reflective, analytical reasoning. A hallmark of the human mind is its ability to engage analytical reasoning, and suppress false associative intuitions. Through a set of laboratory-based network experiments, we find that social learning fails to propagate this cognitive strategy. When people make false intuitive conclusions and are exposed to the analytic output of their peers, they recognize and adopt this correct output. But they fail to engage analytical reasoning in similar subsequent tasks. Thus, humans exhibit an 'unreflective copying bias', which limits their social learning to the output, rather than the process, of their peers' reasoning-even when doing so requires minimal effort and no technical skill. In contrast to much recent work on observation-based social learning, which emphasizes the propagation of successful behaviour through copying, our findings identify a limit on the power of social networks in situations that require analytical reasoning.

  10. Seis sigma no laboratório clínico: impacto na gestão de performance analítica dos processos técnicos Six sigma in clinical laboratory: impact in analytical performance management of technical process

    Directory of Open Access Journals (Sweden)

    Fernando de Almeida Berlitz

    2005-10-01

    Full Text Available INTRODUÇÃO: A visão Seis Sigma da qualidade constitui uma nova ferramenta para o laboratório clínico, objetivando conjugar qualidade de desempenho de processos à gestão de custos. OBJETIVOS: Verificar a viabilidade e o impacto da utilização de conceitos Seis Sigma na gestão de processos técnicos em laboratório clínico. MATERIAIS E MÉTODOS: Foi realizado um estudo comparativo para 14 parâmetros básicos de bioquímica em dois sistemas automatizados, Bayer ADVIA 1650 e Ortho-Clinical Diagnostics VITROS 950, comparando-os em termos de performance analítica com a utilização de métrica sigma, calculada frente a diferentes especificações de desempenho. Resultados: Para ambos os equipamentos avaliados, as maiores métricas foram obtidas para triglicérides (TG e ácido úrico, nas especificações do Clinical Laboratory Improvement Amendments (CLIA e baseadas em variação biológica. As menores métricas foram obtidas para as transaminases (AST e ALT no ADVIA 1650 e para cloretos no VITROS 950. Esses resultados estão em função direta da magnitude das especificações utilizadas no cálculo da métrica sigma. DISCUSSÃO: Os resultados mostraram tendência a melhores índices de performance nos testes realizados no equipamento VITROS 950 em relação aos do ADVIA 1650. A definição do limite de especificação a ser utilizado para cálculo da métrica sigma se mostrou essencial para a adequada avaliação de desempenho analítico dos testes laboratoriais. CONCLUSÕES: A utilização da métrica sigma como índice de performance dos processos técnicos no laboratório clínico proporciona a padronização de um sistema de controle de qualidade custo-efetivo, alinhando qualidade e metas de custo, com foco na satisfação dos clientes e na saúde financeira da organização.BACKGROUND: The Six Sigma approach is a new technique to manage process quality performance in clinical laboratory, aligning quality and cost reduction targets

  11. Semi-analytical MBS Pricing

    DEFF Research Database (Denmark)

    Rom-Poulsen, Niels

    2007-01-01

    interest rate model. However, if the pool size is specified in a way that makes the expectations solvable using transform methods, semi-analytic pricing formulas are achieved. The affine and quadratic pricing frameworks are combined to get flexible and sophisticated prepayment functions. We show...

  12. Laser ablation in analytical chemistry.

    Science.gov (United States)

    Russo, Richard E; Mao, Xianglei; Gonzalez, Jhanis J; Zorba, Vassilia; Yoo, Jong

    2013-07-02

    In 2002, we wrote an Analytical Chemistry feature article describing the Physics of Laser Ablation in Microchemical Analysis. In line with the theme of the 2002 article, this manuscript discusses current issues in fundamental research, applications based on detecting photons at the ablation site (LIBS and LAMIS) and by collecting particles for excitation in a secondary source (ICP), and directions for the technology.

  13. The isfet in analytical chemistry

    NARCIS (Netherlands)

    Schoot, van der B.H.; Bergveld, P.; Bousse, L.J.

    1982-01-01

    The fast chemical response of the pH-ISFET makes the device an excellent detector in analytical chemistry. The time response of ISFETs, with Al2O3 at the pH-sensitive gate insulator, is determined in a flow injection analysis system. Application of an ISFET and a glass electrode are compared in rapi

  14. Faculty Workload: An Analytical Approach

    Science.gov (United States)

    Dennison, George M.

    2012-01-01

    Recent discussions of practices in higher education have tended toward muck-raking and self-styled exposure of cynical self-indulgence by faculty and administrators at the expense of students and their families, as usually occurs during periods of economic duress, rather than toward analytical studies designed to foster understanding This article…

  15. Analytical Sociology: A Bungean Appreciation

    Science.gov (United States)

    Wan, Poe Yu-ze

    2012-01-01

    Analytical sociology, an intellectual project that has garnered considerable attention across a variety of disciplines in recent years, aims to explain complex social processes by dissecting them, accentuating their most important constituent parts, and constructing appropriate models to understand the emergence of what is observed. To achieve…

  16. Analytical SAR-GMTI principles

    Science.gov (United States)

    Soumekh, Mehrdad; Majumder, Uttam K.; Barnes, Christopher; Sobota, David; Minardi, Michael

    2016-05-01

    This paper provides analytical principles to relate the signature of a moving target to parameters in a SAR system. Our objective is to establish analytical tools that could predict the shift and smearing of a moving target in a subaperture SAR image. Hence, a user could identify the system parameters such as the coherent processing interval for a subaperture that is suitable to localize the signature of a moving target for detection, tracking and geolocating the moving target. The paper begins by outlining two well-known SAR data collection methods to detect moving targets. One uses a scanning beam in the azimuth domain with a relatively high PRF to separate the moving targets and the stationary background (clutter); this is also known as Doppler Beam Sharpening. The other scheme uses two receivers along the track to null the clutter and, thus, provide GMTI. We also present results on implementing our SAR-GMTI analytical principles for the anticipated shift and smearing of a moving target in a simulated code. The code would provide a tool for the user to change the SAR system and moving target parameters, and predict the properties of a moving target signature in a subaperture SAR image for a scene that is composed of both stationary and moving targets. Hence, the SAR simulation and imaging code could be used to demonstrate the validity and accuracy of the above analytical principles to predict the properties of a moving target signature in a subaperture SAR image.

  17. Microcomputer Applications in Analytical Chemistry.

    Science.gov (United States)

    Long, Joseph W.

    The first part of this paper addresses the following topics: (1) the usefulness of microcomputers; (2) applications for microcomputers in analytical chemistry; (3) costs; (4) major microcomputer systems and subsystems; and (5) which microcomputer to buy. Following these brief comments, the major focus of the paper is devoted to a discussion of…

  18. Exploratory Analysis in Learning Analytics

    Science.gov (United States)

    Gibson, David; de Freitas, Sara

    2016-01-01

    This article summarizes the methods, observations, challenges and implications for exploratory analysis drawn from two learning analytics research projects. The cases include an analysis of a games-based virtual performance assessment and an analysis of data from 52,000 students over a 5-year period at a large Australian university. The complex…

  19. An Overview of Learning Analytics

    Science.gov (United States)

    Clow, Doug

    2013-01-01

    Learning analytics, the analysis and representation of data about learners in order to improve learning, is a new lens through which teachers can understand education. It is rooted in the dramatic increase in the quantity of data about learners and linked to management approaches that focus on quantitative metrics, which are sometimes antithetical…

  20. Cognitive Analytics Driven Personalized Learning

    Science.gov (United States)

    Gudivada, Venkat N.

    2017-01-01

    Various types of structured data collected by learning management systems such as Moodle have been used to improve student learning outcomes. Learning analytics refers to an assortment of data analysis methods used for this task. These methods typically do not consider unstructured data such as blogs, discussions, e-mail, and course messages.…

  1. Discrete dynamics versus analytic dynamics

    DEFF Research Database (Denmark)

    Toxværd, Søren

    2014-01-01

    For discrete classical Molecular dynamics obtained by the “Verlet” algorithm (VA) with the time increment h there exists a shadow Hamiltonian H˜ with energy E˜(h) , for which the discrete particle positions lie on the analytic trajectories for H˜ . Here, we proof that there, independent...

  2. The Yoccoz Combinatorial Analytic Invariant

    DEFF Research Database (Denmark)

    Petersen, Carsten Lunde; Roesch, Pascale

    2008-01-01

    In this paper we develop a combinatorial analytic encoding of the Mandelbrot set M. The encoding is implicit in Yoccoz' proof of local connectivity of M at any Yoccoz parameter, i.e. any at most finitely renormalizable parameter for which all periodic orbits are repelling. Using this encoding we...

  3. 40 CFR 1065.750 - Analytical gases.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Analytical gases. 1065.750 Section... ENGINE-TESTING PROCEDURES Engine Fluids, Test Fuels, Analytical Gases and Other Calibration Standards § 1065.750 Analytical gases. Analytical gases must meet the accuracy and purity specifications of...

  4. The Gran Sasso Laboratory

    Science.gov (United States)

    Votano, L.

    2012-09-01

    The Gran Sasso underground laboratory is one of the four national laboratories run by the INFN (Istituto Nazionale di Fisica Nucleare). It is located under the Gran Sasso massif, in central Italy, between the cities of L'Aquila and Teramo, 120 km far from Rome. It is the largest underground laboratory for astroparticle physics in the world and the most advanced in terms of complexity and completeness of its infrastructures. The scientific program at the Gran Sasso National Laboratories (Laboratori Nazionali del Gran Sasso, LNGS)is mainly focused on astroparticle, particle and nuclear physics. The laboratory presently hosts many experiments as well as R&D activities, including world-leading research in the fields of solar neutrinos, accelerator neutrinos (CNGS neutrino beam from CERN to Gran Sasso), dark matter, neutrinoless double-beta decay and nuclear cross-section of astrophysical interest. Associate sciences like earth physics, biology and fundamental physics complement the activities. The laboratory is operated as an international science facility and hosts experiments whose scientific merit is assessed by an international advisory Scientific Committee. A review of the main experiments carried out at LNGS will be given, together with the most recent and relevant scientific results achieved.

  5. Analytical Plan for Roman Glasses

    Energy Technology Data Exchange (ETDEWEB)

    Strachan, Denis M.; Buck, Edgar C.; Mueller, Karl T.; Schwantes, Jon M.; Olszta, Matthew J.; Thevuthasan, Suntharampillai; Heeren, Ronald M.

    2011-01-01

    Roman glasses that have been in the sea or underground for about 1800 years can serve as the independent “experiment” that is needed for validation of codes and models that are used in performance assessment. Two sets of Roman-era glasses have been obtained for this purpose. One set comes from the sunken vessel the Iulia Felix; the second from recently excavated glasses from a Roman villa in Aquileia, Italy. The specimens contain glass artifacts and attached sediment or soil. In the case of the Iulia Felix glasses quite a lot of analytical work has been completed at the University of Padova, but from an archaeological perspective. The glasses from Aquileia have not been so carefully analyzed, but they are similar to other Roman glasses. Both glass and sediment or soil need to be analyzed and are the subject of this analytical plan. The glasses need to be analyzed with the goal of validating the model used to describe glass dissolution. The sediment and soil need to be analyzed to determine the profile of elements released from the glass. This latter need represents a significant analytical challenge because of the trace quantities that need to be analyzed. Both pieces of information will yield important information useful in the validation of the glass dissolution model and the chemical transport code(s) used to determine the migration of elements once released from the glass. In this plan, we outline the analytical techniques that should be useful in obtaining the needed information and suggest a useful starting point for this analytical effort.

  6. Laboratory Automation and Middleware.

    Science.gov (United States)

    Riben, Michael

    2015-06-01

    The practice of surgical pathology is under constant pressure to deliver the highest quality of service, reduce errors, increase throughput, and decrease turnaround time while at the same time dealing with an aging workforce, increasing financial constraints, and economic uncertainty. Although not able to implement total laboratory automation, great progress continues to be made in workstation automation in all areas of the pathology laboratory. This report highlights the benefits and challenges of pathology automation, reviews middleware and its use to facilitate automation, and reviews the progress so far in the anatomic pathology laboratory.

  7. Simula Research Laboratory

    CERN Document Server

    Tveito, Aslak

    2010-01-01

    The Simula Research Laboratory, located just outside Oslo in Norway, is rightly famed as a highly successful research facility, despite being, at only eight years old, a very young institution. This fascinating book tells the history of Simula, detailing the culture and values that have been the guiding principles of the laboratory throughout its existence. Dedicated to tackling scientific challenges of genuine social importance, the laboratory undertakes important research with long-term implications in networks, computing and software engineering, including specialist work in biomedical comp

  8. Digital signal processing laboratory

    CERN Document Server

    Kumar, B Preetham

    2011-01-01

    INTRODUCTION TO DIGITAL SIGNAL PROCESSING Brief Theory of DSP ConceptsProblem SolvingComputer Laboratory: Introduction to MATLAB®/SIMULINK®Hardware Laboratory: Working with Oscilloscopes, Spectrum Analyzers, Signal SourcesDigital Signal Processors (DSPs)ReferencesDISCRETE-TIME LTI SIGNALS AND SYSTEMS Brief Theory of Discrete-Time Signals and SystemsProblem SolvingComputer Laboratory: Simulation of Continuous Time and Discrete-Time Signals and Systems ReferencesTIME AND FREQUENCY ANALYSIS OF COMMUNICATION SIGNALS Brief Theory of Discrete-Time Fourier Transform (DTFT), Discrete Fourier Transform

  9. Understanding the interface between clinical and laboratory staff

    Directory of Open Access Journals (Sweden)

    Ankie van den Broek

    2014-04-01

    Full Text Available Background: The interface between clinicians and laboratory staff is where the two meet and work together to provide quality care to their clients (patients. Effectiveness of the interface depends on the way the two groups of professionals relate to and communicate with each other. The number and type of tests requested and the use of the test results for clinical decision making can be influenced by the interface between clinicians and laboratory staff. A model to understand the factors and dynamics around the interface is lacking.Objectives: To propose a new conceptual model to gain insight and analyse factors that influence the laboratory–clinical staff interface.Methods: To develop the conceptual model, a literature study was performed, regulatory guidelines and standards for laboratories were analysed and discussions were held with experts on the topic.Result: A conceptual model and analytical framework provided good guidance in understanding and assessing the organisational and personal factors shaping the interface. The model was based on three elements: (1 the three phases of communication (pre-analytical, analytical and post-analytical; (2 the organisational and personal factors of interaction; and (3 the socio-political, economic and cultural context in which clinicians and laboratory staff operate.Conclusion: Assessment of the interface between clinicians and laboratory workers can be performed in a systematic way. Applying this model will provide information to managers of health institutions and heads of laboratories and clinical departments about what happens when clinicians and laboratory staff interact, thus aiding them in designing strategies to improve this interface. Normal 0 21 false false false NL X-NONE X-NONE

  10. FEASIBILITY OF INVESTMENT IN BUSINESS ANALYTICS

    OpenAIRE

    Mladen Varga; Miljenko Vuković

    2007-01-01

    Trends in data processing for decision support show that business users need business analytics, i.e. analytical applications which incorporate a variety of business oriented data analysis techniques and task-specific knowledge. The paper discusses the feasibility of investment in two models of implementing business analytics: custom development and packed analytical applications. The consequences of both models are shown on two models of business analytics implementation in Croatia.

  11. FEASIBILITY OF INVESTMENT IN BUSINESS ANALYTICS

    Directory of Open Access Journals (Sweden)

    Mladen Varga

    2007-12-01

    Full Text Available Trends in data processing for decision support show that business users need business analytics, i.e. analytical applications which incorporate a variety of business oriented data analysis techniques and task-specific knowledge. The paper discusses the feasibility of investment in two models of implementing business analytics: custom development and packed analytical applications. The consequences of both models are shown on two models of business analytics implementation in Croatia.

  12. Biological Matrix Effects in Quantitative Tandem Mass Spectrometry-Based Analytical Methods: Advancing Biomonitoring

    Science.gov (United States)

    Panuwet, Parinya; Hunter, Ronald E.; D’Souza, Priya E.; Chen, Xianyu; Radford, Samantha A.; Cohen, Jordan R.; Marder, M. Elizabeth; Kartavenka, Kostya; Ryan, P. Barry; Barr, Dana Boyd

    2015-01-01

    The ability to quantify levels of target analytes in biological samples accurately and precisely, in biomonitoring, involves the use of highly sensitive and selective instrumentation such as tandem mass spectrometers and a thorough understanding of highly variable matrix effects. Typically, matrix effects are caused by co-eluting matrix components that alter the ionization of target analytes as well as the chromatographic response of target analytes, leading to reduced or increased sensitivity of the analysis. Thus, before the desired accuracy and precision standards of laboratory data are achieved, these effects must be characterized and controlled. Here we present our review and observations of matrix effects encountered during the validation and implementation of tandem mass spectrometry-based analytical methods. We also provide systematic, comprehensive laboratory strategies needed to control challenges posed by matrix effects in order to ensure delivery of the most accurate data for biomonitoring studies assessing exposure to environmental toxicants. PMID:25562585

  13. Aplikasi Analytical Hierarchy Process Pada Pemilihan Metode Analisis Zat Organik Dalam Air

    Directory of Open Access Journals (Sweden)

    Dino Rimantho

    2016-07-01

    Full Text Available Water is one of the food products analyzed in water chemistry and environmental laboratories. One of the parameters analyzed are organic substances. The number of samples that were not comparable with the analytical skills can cause delays in test results. Analytical Hierarchy Process applied to evaluate the analytical methods used. Alternative methods tested include titrimetric method, spectrophotometry, and total organic carbon (TOC. Respondents consisted of deputy technical manager, laboratory coordinator, and two senior analysts. Alternative results obtained are methods of TOC. Proposed improvements alternative analytical method based on the results obtained, the method of the TOC with a 10-15 minute analysis time and use of CRM to the validity of the analysis results.

  14. Teaching Electronics and Laboratory Automation Using Microcontroller Boards

    Science.gov (United States)

    Mabbott, Gary A.

    2014-01-01

    Modern microcontroller boards offer the analytical chemist a powerful and inexpensive means of interfacing computers and laboratory equipment. The availability of a host of educational materials, compatible sensors, and electromechanical devices make learning to implement microcontrollers fun and empowering. This article describes the advantages…

  15. An Inquiry-Based Density Laboratory for Teaching Experimental Error

    Science.gov (United States)

    Prilliman, Stephen G.

    2012-01-01

    An inquiry-based laboratory exercise is described in which introductory chemistry students measure the density of water five times using either a beaker, a graduated cylinder, or a volumetric pipet. Students are also assigned to use one of two analytical balances, one of which is purposefully miscalibrated by 5%. Each group collects data using…

  16. Environmental monitoring at the Lawrence Livermore Laboratory. 1979 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Silver, W.J.; Lindeken, C.L.; White, J.H.; Buddemeir, R.W.

    1980-04-25

    Information on monitoring activities is reported in two sections for EDB/ERA/INIS. The first section covers all information reported except Appendix D, which gives details of sampling and analytical procedures for environmental monitoring used at Lawrence Livermore Laboratory. A separate abstract was prepared for Appendix D. (JGB)

  17. Strategies for the Successful Implementation of Viral Laboratory Automation

    Science.gov (United States)

    Avivar, Cristóbal

    2012-01-01

    It has been estimated that more than 70% of all medical activity is directly related to information providing analytical data. Substantial technological advances have taken place recently, which have allowed a previously unimagined number of analytical samples to be processed while offering high quality results. Concurrently, yet more new diagnostic determinations have been introduced - all of which has led to a significant increase in the prescription of analytical parameters. This increased workload has placed great pressure on the laboratory with respect to health costs. The present manager of the Clinical Laboratory (CL) has had to examine cost control as well as rationing - meaning that the CL’s focus has not been strictly metrological, as if it were purely a system producing results, but instead has had to concentrate on its efficiency and efficacy. By applying re-engineering criteria, an emphasis has had to be placed on improved organisation and operating practice within the CL, focussing on the current criteria of the Integrated Management Areas where the technical and human resources are brought together. This re-engineering has been based on the concepts of consolidating and integrating the analytical platforms, while differentiating the production areas (CORE Laboratory) from the information areas. With these present concepts in mind, automation and virological treatment, along with serology in general, follow the same criteria as the rest of the operating methodology in the Clinical Laboratory. PMID:23248733

  18. Polybrominated Diphenyl Ethers in Dryer Lint: An Advanced Analysis Laboratory

    Science.gov (United States)

    Thompson, Robert Q.

    2008-01-01

    An advanced analytical chemistry laboratory experiment is described that involves environmental analysis and gas chromatography-mass spectrometry. Students analyze lint from clothes dryers for traces of flame retardant chemicals, polybrominated diphenylethers (PBDEs), compounds receiving much attention recently. In a typical experiment, ng/g…

  19. Laboratory Information Management System (LIMS): A case study

    Science.gov (United States)

    Crandall, Karen S.; Auping, Judith V.; Megargle, Robert G.

    1987-01-01

    In the late 70's, a refurbishment of the analytical laboratories serving the Materials Division at NASA Lewis Research Center was undertaken. As part of the modernization efforts, a Laboratory Information Management System (LIMS) was to be included. Preliminary studies indicated a custom-designed system as the best choice in order to satisfy all of the requirements. A scaled down version of the original design has been in operation since 1984. The LIMS, a combination of computer hardware, provides the chemical characterization laboratory with an information data base, a report generator, a user interface, and networking capabilities. This paper is an account of the processes involved in designing and implementing that LIMS.

  20. Reducing the occurrence of errors in a laboratory's specimen receiving and processing department

    Science.gov (United States)

    Al Saleem, Nouf; Al-Surimi, Khaled

    2016-01-01

    Frequent, preventable medical errors can have an adverse effect on patient safety and quality as well as leading to wasted resources. In the laboratory, errors can occur at any stage of sample processing; pre-analytical, analytical, and post analytical stages. However evidence shows most of the laboratory errors occur during the pre-analytical stage. The receipt and processing of specimens is one of the main steps in the pre-analytical stage. Errors in this stage could be due to mislabeling, incorrect test entry and entering the wrong location, among other reasons. Most of these errors are preventable. At the Riyadh Regional Laboratory of the Ministry of Health, we found that there was an average of 2.31 errors per 1000 processed samples; these errors had occurred during the pre-analytical stage. These samples were returned back from other laboratory departments, such as Chemistry, Hematology and Microbiology, to the receiving and processing department. We decided to carry out an improvement project where we applied a systematic approach to identify and analyse the root causes of the problem using quality tools such as a process flowchart and a fish-bone diagram. The Model for Improvement was used and several PDSA (Plan, Do, Study, Act) cycles were run to test interventions which aimed to prevent laboratory processing errors and mistakes. The project results showed a 25% reduction in errors during the pre-analytical stage. PMID:27752311

  1. Structural Static Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Structural testing is performed to verify the structural integrity of space flight and ground test hardware. Testing is also performed to verify the finite element...

  2. GSPEL - Calorimeter Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Testing performance claims on heat transfer components The Calorimeter Lab, located in the Ground Systems Power and Energy Lab (GSPEL), is one of the largest in the...

  3. Understanding Laboratory Tests

    Science.gov (United States)

    ... and Drug Administration (FDA) regulates the development and marketing of all laboratory tests that use test kits ... are of great interest in cancer medicine because research suggests that levels of ... sequencing methods are being developed to provide gene mutation profiles ...

  4. European Molecular Biology Laboratory

    CERN Multimedia

    1973-01-01

    On 10 May an Agreement was signed at CERN setting up a new European Laboratory. It will be concerned with research in molecularbiology and will be located at Heidelberg in the Federal Republic of Germany.

  5. Immersive Simulation Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Develops and tests novel user interfaces for 3D virtual simulators and first-person shooter games that make user interaction more like natural interaction...

  6. Alloy Fabrication Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — At NETL’s Alloy Fabrication Facility in Albany, OR, researchers conduct DOE research projects to produce new alloys suited to a variety of applications, from gas...

  7. GSPEL - Fuel Cell Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Fuel Cell Lab (FCL) Provides testing for technology readiness of fuel cell systems The FCL investigates, tests and verifies the performance of fuel-cell systems...

  8. GSPEL - Calorimeter Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Testing performance claims on heat transfer componentsThe Calorimeter Lab, located in the Ground Systems Power and Energy Lab (GSPEL), is one of the largest in the...

  9. Physics Laboratory in UEC

    Science.gov (United States)

    Takada, Tohru; Nakamura, Jin; Suzuki, Masaru

    All the first-year students in the University of Electro-Communications (UEC) take "Basic Physics I", "Basic Physics II" and "Physics Laboratory" as required subjects; Basic Physics I and Basic Physics II are calculus-based physics of mechanics, wave and oscillation, thermal physics and electromagnetics. Physics Laboratory is designed mainly aiming at learning the skill of basic experimental technique and technical writing. Although 95% students have taken physics in the senior high school, they poorly understand it by connecting with experience, and it is difficult to learn Physics Laboratory in the university. For this reason, we introduced two ICT (Information and Communication Technology) systems of Physics Laboratory to support students'learning and staff's teaching. By using quantitative data obtained from the ICT systems, we can easily check understanding of physics contents in students, and can improve physics education.

  10. Fritz Engineering Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Features 800,000 lb and 5,000,000 lb universal testing machines, and a dynamic test bed with broad fatigue-testing capabilities, and a wide range of instrumentation....

  11. GSPEL - Air Filtration Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Evaluation capabilities for air filtration devicesThe Air Filtration Lab provides testing of air filtration devices to demonstrate and validate new or legacy system...

  12. Geocentrifuge Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The geocentrifuge subjects a sample to a high-gravity field by spinning it rapidly around a central shaft. In this high-gravity field, processes, such as fluid flow,...

  13. Key Management Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides a secure environment to research and develop advanced electronic key management and networked key distribution technologies for the Navy and DoD....

  14. GSPEL - Fuel Cell Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Fuel Cell Lab (FCL)Provides testing for technology readiness of fuel cell systems The FCL investigates, tests and verifies the performance of fuel-cell systems...

  15. Inorganic Coatings Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The inorganic Coatings Lab provides expertise to Navy and Joint Service platforms acquisition IPTs to aid in materials and processing choices which balance up-front...

  16. New software solutions for analytical spectroscopists

    Science.gov (United States)

    Davies, Antony N.

    1999-05-01

    Analytical spectroscopists must be computer literate to effectively carry out the tasks assigned to them. This has often been resisted within organizations with insufficient funds to equip their staff properly, a lack of desire to deliver the essential training and a basic resistance amongst staff to learn the new techniques required for computer assisted analysis. In the past these problems were compounded by seriously flawed software which was being sold for spectroscopic applications. Owing to the limited market for such complex products the analytical spectroscopist often was faced with buying incomplete and unstable tools if the price was to remain reasonable. Long product lead times meant spectrometer manufacturers often ended up offering systems running under outdated and sometimes obscure operating systems. Not only did this mean special staff training for each instrument where the knowledge gained on one system could not be transferred to the neighbouring system but these spectrometers were often only capable of running in a stand-alone mode, cut-off from the rest of the laboratory environment. Fortunately a number of developments in recent years have substantially changed this depressing picture. A true multi-tasking operating system with a simple graphical user interface, Microsoft Windows NT4, has now been widely introduced into the spectroscopic computing environment which has provided a desktop operating system which has proved to be more stable and robust as well as requiring better programming techniques of software vendors. The opening up of the Internet has provided an easy way to access new tools for data handling and has forced a substantial re-think about results delivery (for example Chemical MIME types, IUPAC spectroscopic data exchange standards). Improved computing power and cheaper hardware now allows large spectroscopic data sets to be handled without too many problems. This includes the ability to carry out chemometric operations in

  17. Lighting – laboratory practice

    Directory of Open Access Journals (Sweden)

    Борис Васильевич Дзюндзюк

    2014-10-01

    Full Text Available In this article discussed one of the possible variants of the building study bench for laboratory work and practical lessons on the basic parameters of the study of artificial and natural lighting in the labour protection in accordance with the DBN V.2.5-28-2006. The model is on the latest LED components, which has high reliability, maintainability and eliminates the disadvantages of the existing laboratory stands.

  18. Analytical Support, Characterization, and Optimization of a Canine Training Aid Delivery System: Phase 2

    Science.gov (United States)

    2016-01-29

    analyte held within the MODD, consecutive collections were made using 1 L VeriAir Flex manual inflating sample bags ( Environmental Monitoring...Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/6180--16-9657 Analytical Support, Characterization, and Optimization of a Canine Training...Technology Center for Safety and Survivability Chemistry Division MichaEL MaLito chriStoPhEr J. KatiLiE Nova Research, Inc. Alexandria, Virginia i

  19. Analytical evaluation of the clinical chemistry analyzer Olympus AU2700 plus

    OpenAIRE

    Juricek, Jasna; Derek, Lovorka; Unic, Adriana; Serdar, Tihana; Marijancevic, Domagoj; Zivkovic, Marcela; Romic, Zeljko

    2010-01-01

    Background: The objective of this study was to perform the analytical evaluation of the clinical chemistry analyzer Olympus AU2700 plus. The evaluation was performed according to the guidelines of the European Committee for Clinical Laboratory Standards (ECCLS). Materials and methods: The evaluation consisted of determination of within-run and between-run imprecision, inaccuracy and comparison with Olympus AU2700. The tested analytes were: glucose, creatinine, urate, total bilirubin, chole...

  20. A typology of evidence based practice research heuristics for clinical laboratory science curricula.

    Science.gov (United States)

    Leibach, Elizabeth K; Russell, Barbara L

    2010-01-01

    A typology of EBP research heuristics was defined relative to clinical laboratory science levels of practice. Research skills requisite for CLS baccalaureate level are associated mainly with quality control of analytic processes. Research skills at master's level are associated with pre- and post-analytic investigations, as well. Doctoral level CLS practice portends to utilize research skills facilitating quality investigations at the systems level.

  1. Are They Really Sloppy?: A Comparative Analysis of Student Performance in the Laboratory

    Science.gov (United States)

    Kovács-Hadady, Katalin; Fábián, István

    1996-05-01

    The performance of the students in the analytical laboratory was tested in a potentiometric determination of fluoride ion in anti-caries dental tablets. The analytical results determined by freshman students and experienced personnel were compared. The error in the student's experiments was only about two times bigger than in the reference determinations. The lack of experience mainly affected students in complex tasks.

  2. 76 FR 161 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-01-03

    ....) Maxxam Analytics,\\*\\ 6740 Campobello Road, Mississauga, ON, Canada L5N 2L8.905-817-5700. (Formerly: Maxxam Analytics Inc., NOVAMANN (Ontario), Inc.) * The Standards Council of Canada (SCC) voted to end its.... Toxicology & Drug Monitoring Laboratory, University of Missouri Hospital & Clinics, 301 Business Loop 70...

  3. 78 FR 314 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-01-03

    ... Monitoring Laboratory, University of Missouri Hospital & Clinics, 301 Business Loop 70 West, Suite 208... the NLCP on December 31, 2012: Maxxam Analytics,* 6740 Campobello Road, Mississauga, ON, Canada L5N 2L8, 905-817-5700, (Formerly: Maxxam Analytics Inc., NOVAMANN (Ontario), Inc.) * The Standards...

  4. Call for Enrolling More Professionals in the IFCC Project on Laboratory Errors and Patient Safety.

    Science.gov (United States)

    Plebani, Mario; Laura, Sciacovelli

    2011-03-01

    Patient safety is the foundation of good care. In the last decades, a body of evidence has been accumulated to demonstrate that pre- and post-analytical phase are more vulnerable to errors in laboratory medicine than the analytical phase. Aims of the project of the IFCC Working Group on "Laboratory Errors and Patient Safety" (WG-LEPS) are: a) to develop a series of Quality Indicators (QIs), specifically designed for clinical laboratories, b) to create a common reporting system for clinical laboratories based on standardized data collection, and c) to define state-of the-art and Quality Specifications (QSs) for each QI Preliminary results demonstrate that a Model of Quality Indicators can serve as a tool to monitor and control the pre-, intra- and post-analytical activities. However, only after enrolling a more consistent number of clinical laboratories, it should be possible to assure consistency to the data collected and reliability to the QIs identified and to related QSs.

  5. Analytic bootstrap at large spin

    CERN Document Server

    Kaviraj, Apratim; Sinha, Aninda

    2015-01-01

    We use analytic conformal bootstrap methods to determine the anomalous dimensions and OPE coefficients for large spin operators in general conformal field theories in four dimensions containing a scalar operator of conformal dimension $\\Delta_\\phi$. It is known that such theories will contain an infinite sequence of large spin operators with twists approaching $2\\Delta_\\phi+2n$ for each integer $n$. By considering the case where such operators are separated by a twist gap from other operators at large spin, we analytically determine the $n$, $\\Delta_\\phi$ dependence of the anomalous dimensions. We find that for all $n$, the anomalous dimensions are negative for $\\Delta_\\phi$ satisfying the unitarity bound, thus extending the Nachtmann theorem to non-zero $n$. In the limit when $n$ is large, we find agreement with the AdS/CFT prediction corresponding to the Eikonal limit of a 2-2 scattering with dominant graviton exchange.

  6. Video Analytics for Business Intelligence

    CERN Document Server

    Porikli, Fatih; Xiang, Tao; Gong, Shaogang

    2012-01-01

    Closed Circuit TeleVision (CCTV) cameras have been increasingly deployed pervasively in public spaces including retail centres and shopping malls. Intelligent video analytics aims to automatically analyze content of massive amount of public space video data and has been one of the most active areas of computer vision research in the last two decades. Current focus of video analytics research has been largely on detecting alarm events and abnormal behaviours for public safety and security applications. However, increasingly CCTV installations have also been exploited for gathering and analyzing business intelligence information, in order to enhance marketing and operational efficiency. For example, in retail environments, surveillance cameras can be utilised to collect statistical information about shopping behaviour and preference for marketing (e.g., how many people entered a shop; how many females/males or which age groups of people showed interests to a particular product; how long did they stay in the sho...

  7. Library improvement through data analytics

    CERN Document Server

    Farmer, Lesley S J

    2017-01-01

    This book shows how to act on and make sense of data in libraries. Using a range of techniques, tools and methodologies it explains how data can be used to help inform decision making at every level. Sound data analytics is the foundation for making an evidence-based case for libraries, in addition to guiding myriad organizational decisions, from optimizing operations for efficiency to responding to community needs. Designed to be useful for beginners as well as those with a background in data, this book introduces the basics of a six point framework that can be applied to a variety of library settings for effective system based, data-driven management. Library Improvement Through Data Analytics includes: - the basics of statistical concepts - recommended data sources for various library functions and processes, and guidance for using census, university, or - - government data in analysis - techniques for cleaning data - matching data to appropriate data analysis methods - how to make descriptive statistics m...

  8. Analytical Spectroscopy Using Modular Systems

    Science.gov (United States)

    Patterson, Brian M.; Danielson, Neil D.; Lorigan, Gary A.; Sommer, André J.

    2003-12-01

    This article describes the development of three analytical spectroscopy experiments that compare the determination of salicylic acid (SA) content in aspirin tablets. The experiments are based on UV vis, fluorescence, and Raman spectroscopies and utilize modular spectroscopic components. Students assemble their own instruments, optimize them with respect to signal-to-noise, generate calibration curves, determine the SA content in retail aspirin tablets, and assign features in the respective spectra to functional groups within the active material. Using this approach in the discovery-based setting, the students gain invaluable insight into method-specific parameters, such as instrumental components, sample preparation, and analytical capability. In addition, the students learn the fundamentals of fiber optics and signal processing using the low-cost CCD based spectroscopic components.

  9. Visual Analytics for MOOC Data.

    Science.gov (United States)

    Qu, Huamin; Chen, Qing

    2015-01-01

    With the rise of massive open online courses (MOOCs), tens of millions of learners can now enroll in more than 1,000 courses via MOOC platforms such as Coursera and edX. As a result, a huge amount of data has been collected. Compared with traditional education records, the data from MOOCs has much finer granularity and also contains new pieces of information. It is the first time in history that such comprehensive data related to learning behavior has become available for analysis. What roles can visual analytics play in this MOOC movement? The authors survey the current practice and argue that MOOCs provide an opportunity for visualization researchers and that visual analytics systems for MOOCs can benefit a range of end users such as course instructors, education researchers, students, university administrators, and MOOC providers.

  10. Analytic continuation of Toeplitz operators

    OpenAIRE

    Bommier-Hato, H.; Engliš, M. (Miroslav); Youssfi, E.-H.

    2015-01-01

    Generalizing results of Rossi and Vergne for the holomorphic discrete series on symmetric domains, on the one hand, and of Chailuek and Hall for Toeplitz operators on the ball, on the other hand, we establish existence of analytic continuation of weighted Bergman spaces, in the weight (Wallach) parameter, as well as of the associated Toeplitz operators (with sufficiently nice symbols), on any smoothly bounded strictly pseudoconvex domain. Still further extension to Sobolev spaces of holomorph...

  11. Spin coherence time analytical estimations

    CERN Document Server

    Orlov, Yuri

    2015-01-01

    Section I presents a variety of analytical estimations related to spin coherence time (SCT) in a purely electric frozen-spin ring. The main result is that, in the case of m > 0 and vertical oscillations only, the kinetic energy equilibrium shift equals zero, that is, SCT does not depend on these oscillations. Section II contains additional information on this case concerning terminology, electric field definition and vertical oscillations.

  12. Learning Analytics: opportunities for schools

    Directory of Open Access Journals (Sweden)

    Giovanni Fulantelli

    2014-12-01

    Full Text Available La valutazione delle esperienze di apprendimento che avvengono in ambienti in cui le interazioni sono mediate dalle tecnologie è una sfida ardua che deve essere affrontata con approcci adeguati. Le tecniche di Learning Analytics si sono sviluppate recentemente con l’obiettivo di fornire gli strumenti necessari per ottimizzare le esperienze di apprendimento. Queste tecniche supportano i docenti nel prendere tempestivamente quelle decisioni che rendono il processo didattico più efficace, permettendo di intervenire sull’intero processo o sui singoli studenti in modo personalizzato. Sebbene le tecniche di Learning Analytics si siano sviluppate principalmente nei contesti di alta formazione online, questo articolo mette in evidenza come l’impiego di tali tecniche può portare benefici anche nei contesti scolastici. Di fatto, in questi contesti, le tecnologie sono sempre più utilizzate per supportare le esperienze di apprendimento formali e informali, come quelle basate su dispositivi mobili, serious game e social network, e i dati generati sono sempre più numerosi, richiedendo nuovi approcci di analisi che traggono vantaggio dall’impiego delle tecniche di Learning Analytics.

  13. CERTS Microgrid Laboratory Test Bed

    Energy Technology Data Exchange (ETDEWEB)

    Lasseter, R. H.; Eto, J. H.; Schenkman, B.; Stevens, J.; Volkmmer, H.; Klapp, D.; Linton, E.; Hurtado, H.; Roy, J.

    2010-06-08

    CERTS Microgrid concept captures the emerging potential of distributed generation using a system approach. CERTS views generation and associated loads as a subsystem or a 'microgrid'. The sources can operate in parallel to the grid or can operate in island, providing UPS services. The system can disconnect from the utility during large events (i.e. faults, voltage collapses), but may also intentionally disconnect when the quality of power from the grid falls below certain standards. CERTS Microgrid concepts were demonstrated at a full-scale test bed built near Columbus, Ohio and operated by American Electric Power. The testing fully confirmed earlier research that had been conducted initially through analytical simulations, then through laboratory emulations, and finally through factory acceptance testing of individual microgrid components. The islanding and resynchronization method met all Institute of Electrical and Electronics Engineers Standard 1547 and power quality requirements. The electrical protection system was able to distinguish between normal and faulted operation. The controls were found to be robust under all conditions, including difficult motor starts and high impedance faults.

  14. LIMS use in laboratory data management

    Directory of Open Access Journals (Sweden)

    Muntean Edward

    2008-12-01

    Full Text Available Laboratory data management is a complex process involving both people and information in order toacquire, organize, store and distribute information. Information conversion to knowledge requires the applicationof many human qualities such as experience, intelligence, intuition and talent; it is not enough to simply acquireand own data, being necessary to have a proper understanding of the data structure and the required qualities toapply a suitable management system. Modern laboratories produce large amounts of data; with the continuousdevelopment of new technologies, both the quality and quantity of information is increasing, causing oftensignificant problems and new methods are needed to manage this situation. Laboratory Information ManagementSystems (LIMS provides a way of automating part of the laboratory system. As the primary function of mostlaboratories is to provide validated information under some time constraints and based on that information,allowing customers to make decisions, LIMS can save considerable amounts of time and dramatically improvethe level of data access for all individuals involved in a given project; the sooner the user is notified of aproblem, the sooner that problem can be fixed and the less the solution will cost. Several of the main benefitsidentified from current users of LIMS are: analytical data can be obtained instantly being also easily accessibleonline; large amounts of data can be stored without the need for traditional archiving; improvement of dataquality as all the analytical instruments are integrated; automated tracking and management; automated customerreports; automated quality control. All these benefits can lead finally to a general improvement of laboratoryefficiency. Despite LIMS have been used for more than twenty years, they still remain difficult to implementsuccessfully. This paper provides a brief description of some of the existing technologies available to date,detailing the benefits that

  15. Green analytical chemistry--theory and practice.

    Science.gov (United States)

    Tobiszewski, Marek; Mechlińska, Agata; Namieśnik, Jacek

    2010-08-01

    This tutorial review summarises the current state of green analytical chemistry with special emphasis on environmentally friendly sample preparation techniques. Green analytical chemistry is a part of the sustainable development concept; its history and origins are described. Miniaturisation of analytical devices and shortening the time elapsing between performing analysis and obtaining reliable analytical results are important aspects of green analytical chemistry. Solventless extraction techniques, the application of alternative solvents and assisted extractions are considered to be the main approaches complying with green analytical chemistry principles.

  16. Nuclear analytical techniques for nanotoxicology studies

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Z.Y.; Zhao, Y.L.; Chai, Z.F. [Chinese Academy of Sciences, Beijing (China). Key Lab for Biomedical Effects of Nanomaterials and Nanosafety

    2011-07-01

    With the rapid development of nanotechnology and its applications, a wide variety of nanomaterials are now used in commodities, pharmaceutics, cosmetics, biomedical products, and industries. The potential interactions of nanomaterials with living systems and the environment have attracted increasing attention from the public, as well as from manufacturers of nanomaterial-based products, academic researchers and policymakers. It is important to consider the environmental, health and safety aspects at an early stage of nanomaterial development and application in order to more effectively identify and manage potential human and environmental health impacts from nanomaterial exposure. This will require research in a range of areas, including detection and characterization, environmental fate and transport, ecotoxicology and toxicology. Nuclear analytical techniques (NATs) can play an important role in such studies due to their intrinsic merits such as high sensitivity, good accuracy, high space resolution, ability to distinguish the endogenous or exogenous sources of materials, and ability of in situ and in vivo analysis. In this paper, the applications of NATs in nanotoxicological and nano-ecotoxicological studies are outlined, and some recent results obtained in our laboratory are reported. (orig.)

  17. Strictly analytic functions on p-adic analytic open sets

    OpenAIRE

    Boussaf, Kamal

    1999-01-01

    Let K be an algebraically closed complete ultrametric field. M. Krasner and P. Robba defined theories of analytic functions in K, but when K is not spherically complete both theories have the disadvantage of containing functions that may not be expanded in Taylor series in some disks. On other hand, affinoid theories are only defined in a small class of sets (union of affinoid sets) [2], [13] and [17]. Here, we suppose the field K topologically separable (example Cp). Then, we give a new defi...

  18. AN ANALYTICAL SOLUTION FOR CALCULATING THE INITIATION OF SEDIMENT MOTION

    Institute of Scientific and Technical Information of China (English)

    Thomas LUCKNER; Ulrich ZANKE

    2007-01-01

    This paper presents an analytical solution for calculating the initiation of sediment motion and the risk of river bed movement. It thus deals with a fundamental problem in sediment transport, for which no complete analytical solution has yet been found. The analytical solution presented here is based on forces acting on a single grain in state of initiation of sediment motion. The previous procedures for calculating the initiation of sediment motion are complemented by an innovative combination of optical surface measurement technology for determining geometrical parameters and their statistical derivation as well as a novel approach for determining the turbulence effects of velocity fluctuations. This two aspects and the comparison of the solution functions presented here with the well known data and functions of different authors mainly differ the presented solution model for calculating the initiation of sediment motion from previous approaches. The defined values of required geometrical parameters are based on hydraulically laboratory tests with spheres. With this limitations the derivated solution functions permit the calculation of the effective critical transport parameters of a single grain, the calculation of averaged critical parameters for describing the state of initiation of sediment motion on the river bed, the calculation of the probability density of the effective critical velocity as well as the calculation of the risk of river bed movement. The main advantage of the presented model is the closed analytical solution from the equilibrium of forces on a single grain to the solution functions describing the initiation of sediment motion.

  19. San Juan District Laboratory (SJN)

    Data.gov (United States)

    Federal Laboratory Consortium — Program Capabilities SJN-DO Pharmaceutical Laboratory is an A2LA/ISO/IEC 17025 accredited National Servicing Laboratory specialized in Drug Analysis, is a member of...

  20. San Juan District Laboratory (SJN)

    Data.gov (United States)

    Federal Laboratory Consortium — Program CapabilitiesSJN-DO Pharmaceutical Laboratory is an A2LA/ISO/IEC 17025 accredited National Servicing Laboratory specialized in Drug Analysis, is a member of...