WorldWideScience

Sample records for analysis final progress

  1. Final Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Josef Michl

    2011-10-31

    In this project we have established guidelines for the design on organic chromophores suitable for producing high triplet yields via singlet fission. We have proven their utility by identifying a chromophore of a structural class that had never been examined for singlet fission before, 1,3-diphenylisobenzofuran, and demonstrating in two independent ways that a thin layer of this material produces a triplet yield of 200% within experimental error. We have also designed a second chromophore of a very different type, again of a structural class that had not been examined for singlet fission before, and found that in a thin layer it produces a 70% triplet yield. Finally, we have enhanced the theoretical understanding of the quantum mechanical nature of the singlet fission process.

  2. Final Performance Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Houldin, Joseph [Delaware Valley Industrial Resource Center, Philadelphia, PA (United States); Saboor, Veronica [Delaware Valley Industrial Resource Center, Philadelphia, PA (United States)

    2016-03-30

    about assessing a company’s technical assets, broadening our view of the business to go beyond what they make or what NAICS code they have…to better understand their capacity, capability, and expertise, and to learn more about THEIR customers. Knowing more about the markets they serve can often provide insight into their level of technical knowledge and sophistication. Finally, in the spirit of realizing the intent of the Accelerator we strove to align and integrate the work and activities supported by the five funding agencies to leverage each effort. To that end, we include in the Integrated Work Plan a graphic that illustrates that integration. What follows is our summary report of the project, aggregated from prior reports.

  3. Final Progress Report for 'An Abstract Job Handling Grid Service for Dataset Analysis'

    International Nuclear Information System (INIS)

    For Phase I of the Job Handling project, Tech-X has built a Grid service for processing analysis requests, as well as a Graphical User Interface (GUI) client that uses the service. The service is designed to generically support High-Energy Physics (HEP) experimental analysis tasks. It has an extensible, flexible, open architecture and language. The service uses the Solenoidal Tracker At RHIC (STAR) experiment as a working example. STAR is an experiment at the Relativistic Heavy Ion Collider (RHIC) at the Brookhaven National Laboratory (BNL). STAR and other experiments at BNL generate multiple Petabytes of HEP data. The raw data is captured as millions of input files stored in a distributed data catalog. Potentially using thousands of files as input, analysis requests are submitted to a processing environment containing thousands of nodes. The Grid service provides a standard interface to the processing farm. It enables researchers to run large-scale, massively parallel analysis tasks, regardless of the computational resources available in their location

  4. IRIS Final Technical Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    M. D. Carelli

    2003-11-03

    OAK-B135 This NERI project, originally started as the Secure Transportable Autonomous Light Water Reactor (STAR-LW) and currently known as the International Reactor Innovative and Secure (IRIS) project, had the objective of investigating a novel type of water-cooled reactor to satisfy the Generation IV goals: fuel cycle sustainability, enhanced reliability and safety, and improved economics. The research objectives over the three-year (1999-2002) program were as follows: First year: Assess various design alternatives and establish main characteristics of a point design; Second year: Perform feasibility and engineering assessment of the selected design solutions; Third year: Complete reactor design and performance evaluation, including cost assessment These objectives were fully attained and actually they served to launch IRIS as a full fledged project for eventual commercial deployment. The program did not terminate in 2002 at the end of the NERI program, and has just entered in its fifth year. This has been made possible by the IRIS project participants which have grown from the original four member, two-countries team to the current twenty members, nine countries consortium. All the consortium members work under their own funding and it is estimated that the value of their in-kind contributions over the life of the project has been of the order of $30M. Currently, approximately 100 people worldwide are involved in the project. A very important constituency of the IRIS project is the academia: 7 universities from four countries are members of the consortium and five more US universities are associated via parallel NERI programs. To date, 97 students have worked or are working on IRIS; 59 IRIS-related graduate theses have been prepared or are in preparation, and 41 of these students have already graduated with M.S. (33) or Ph.D. (8) degrees. This ''final'' report (final only as far as the NERI program is concerned) summarizes the work performed

  5. 1995 PVUSA progress report. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Photovoltaics for Utility Scale Applications (PVUSA) is a national public-private partnership that is assessing and demonstrating the viability of utility-scale (US) photovoltaic (PV) electric generation systems and recent developments in PV module technology. This report updates the project`s progress, reviews the status and performance of the various PV installations during 1995, summarizes key accomplishments and conclusions, and serves as the final report under Pacific Gas and Electric Company`s project management.

  6. Chromosome region-specific libraries for human genome analysis. Final progress report, 1 March 1991--28 February 1994

    Energy Technology Data Exchange (ETDEWEB)

    Kao, F.T.

    1994-04-01

    The objectives of this grant proposal include (1) development of a chromosome microdissection and PCR-mediated microcloning technology, (2) application of this microtechnology to the construction of region-specific libraries for human genome analysis. During this grant period, the authors have successfully developed this microtechnology and have applied it to the construction of microdissection libraries for the following chromosome regions: a whole chromosome 21 (21E), 2 region-specific libraries for the long arm of chromosome 2, 2q35-q37 (2Q1) and 2q33-q35 (2Q2), and 4 region-specific libraries for the entire short arm of chromosome 2, 2p23-p25 (2P1), 2p21-p23 (2P2), 2p14-p16 (wP3) and 2p11-p13 (2P4). In addition, 20--40 unique sequence microclones have been isolated and characterized for genomic studies. These region-specific libraries and the single-copy microclones from the library have been used as valuable resources for (1) isolating microsatellite probes in linkage analysis to further refine the disease locus; (2) isolating corresponding clones with large inserts, e.g. YAC, BAC, P1, cosmid and phage, to facilitate construction of contigs for high resolution physical mapping; and (3) isolating region-specific cDNA clones for use as candidate genes. These libraries are being deposited in the American Type Culture Collection (ATCC) for general distribution.

  7. Schedulability Analysis for Java Finalizers

    DEFF Research Database (Denmark)

    Bøgholm, Thomas; Hansen, Rene Rydhof; Ravn, Anders P.;

    2010-01-01

    the schedulability analysis. In this paper we show that a controlled scoped memory model results in a structured and predictable execution of finalizers, more reminiscent of C++ destructors than Java finalizers. Furthermore, we incorporate finalizers into a (conservative) schedulability analysis for...... Predictable Java programs. Finally, we extend the SARTS tool for automated schedulability analysis of Java bytecode programs to handle finalizers in a fully automated way....

  8. Federal Assistance Program Quarterly Project Progress Report. Geothermal Energy Program: Information Dissemination, Public Outreach, and Technical Analysis Activities. Reporting Period: January 1 - March 31, 2001 [Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lund, John W.

    2002-03-22

    The final report of the accomplishments of the geothermal energy program: information dissemination, public outreach and technical analysis activities by the project team consisting of the Geo-Heat Center, Geothermal Resources Council, Geothermal Education Office, Geothermal Energy Association and the Washington State University Energy Program.

  9. Hanford Site pollution prevention progress report; FINAL

    International Nuclear Information System (INIS)

    The Richland Operations Office (RL) and Office of River Protection (ORP) are pleased to issue the attached Pollution Prevention Progress Report. We have just met the most aggressive waste reduction and A recycling goals to date and are publishing this report to recognize A the site's progress, and to ensure it will sustain success beyond 1 Fiscal Year 2000. This report was designed to inform the been made by RL and ORP in Waste Minimization (WMin) and Pollution Prevention (P2). RL, ORP and their contractors are committed to protecting the environment, and we reiterate pollution prevention should continue to be at the forefront of the environmental cleanup and research efforts. As you read the attached report, we believe you will see a clear demonstration of RL and ORP's outstanding performance as it has been responsible and accountable to the nation, its employees, and the community in which we live and work. commitment that all employees have for environmental stewardship. The report provides useful information about the U.S. Department of Energy's (DOE'S) environmental policy and programs, and contains countless examples of waste minimization projects. This year was the first year our site received the White House Closing the Circle in the category of Affirmative Procurement. This Award recognizes our site for designing a comprehensive strategy for achieving 100 percent purchases of the U.S.Environmenta1 Protection Agency designated recycled items. DOE-Headquarters also acknowledged the site in 1999 for its public outreach efforts in communicating pollution prevention to Hanford Site employees and the community. Our site is truly a recognized leader in outreach as it has kept this title for two consecutive years. In previous years, we received the White House Closing the Circle Honorable Mention in Affirmative Procurement and several other National DOE Awards. Through partnership with the local community and stakeholders, the site and its contractors have a clear

  10. Schedulability Analysis for Java Finalizers

    DEFF Research Database (Denmark)

    Bøgholm, Thomas; Hansen, Rene Rydhof; Søndergaard, Hans;

    2010-01-01

    Java finalizers perform clean-up and finalisation of objects at garbage collection time. In real-time Java profiles the use of finalizers is either discouraged (RTSJ, Ravenscar Java) or even disallowed (JSR-302), mainly because of the unpredictability of finalizers and in particular their impact...... on the schedulability analysis. In this paper we show that a controlled scoped memory model results in a structured and predictable execution of finalizers, more reminiscent of C++ destructors than Java finalizers. Furthermore, we incorporate finalizers into a (conservative) schedulability analysis for Predictable Java...... programs. Finally, we extend the SARTS tool for automated schedulability analysis of Java bytecode programs to handle finalizers in a fully automated way....

  11. Studies in genetic discrimination. Final progress report

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    We have screened 1006 respondents in a study of genetic discrimination. Analysis of these responses has produced evidence of the range of institutions engaged in genetic discrimination and demonstrates the impact of this discrimination on the respondents to the study. We have found that both ignorance and policy underlie genetic discrimination and that anti-discrimination laws are being violated.

  12. Analysis and control of the METC fluid bed gasifier. Final report (includes technical progress report for October 1994--January 1995), September 1994--September 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    This document presents a modeling and control study of the Fluid Bed Gasification (FBG) unit at the Morgantown Energy Technology Center (METC). The work is performed under contract no. DE-FG21-94MC31384. The purpose of this study is to generate a simple FBG model from process data, and then use the model to suggest an improved control scheme which will improve operation of the gasifier. The work first developes a simple linear model of the gasifier, then suggests an improved gasifier pressure and MGCR control configuration, and finally suggests the use of a multivariable control strategy for the gasifier.

  13. Integrated sequence analysis. Final report

    International Nuclear Information System (INIS)

    The NKS/RAK subprojet 3 'integrated sequence analysis' (ISA) was formulated with the overall objective to develop and to test integrated methodologies in order to evaluate event sequences with significant human action contribution. The term 'methodology' denotes not only technical tools but also methods for integration of different scientific disciplines. In this report, we first discuss the background of ISA and the surveys made to map methods in different application fields, such as man machine system simulation software, human reliability analysis (HRA) and expert judgement. Specific event sequences were, after the surveys, selected for application and testing of a number of ISA methods. The event sequences discussed in the report were cold overpressure of BWR, shutdown LOCA of BWR, steam generator tube rupture of a PWR and BWR disturbed signal view in the control room after an external event. Different teams analysed these sequences by using different ISA and HRA methods. Two kinds of results were obtained from the ISA project: sequence specific and more general findings. The sequence specific results are discussed together with each sequence description. The general lessons are discussed under a separate chapter by using comparisons of different case studies. These lessons include areas ranging from plant safety management (design, procedures, instrumentation, operations, maintenance and safety practices) to methodological findings (ISA methodology, PSA,HRA, physical analyses, behavioural analyses and uncertainty assessment). Finally follows a discussion about the project and conclusions are presented. An interdisciplinary study of complex phenomena is a natural way to produce valuable and innovative results. This project came up with structured ways to perform ISA and managed to apply the in practice. The project also highlighted some areas where more work is needed. In the HRA work, development is required for the use of simulators and expert judgement as

  14. Recent progress in analysis for fission products

    International Nuclear Information System (INIS)

    A great deal of progress has been achieved in analysis of fission products during the 1980s. In situ analysis of fission products and direct assay of radiowaste packages have been developed to meet the needs of radiowaste treatment and disposal. Activation analysis and non-radiometric method have been used to measure long-lived fission product nuclides. Their sensitivity is superior to that of traditional radiochemical analysis. Some new work on the Cherenkov counting technique and rapid radiochemical analysis has been published. The progress is reviewed from the point of view of methodology

  15. Integrated sequence analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, K.; Pyy, P

    1998-02-01

    The NKS/RAK subprojet 3 `integrated sequence analysis` (ISA) was formulated with the overall objective to develop and to test integrated methodologies in order to evaluate event sequences with significant human action contribution. The term `methodology` denotes not only technical tools but also methods for integration of different scientific disciplines. In this report, we first discuss the background of ISA and the surveys made to map methods in different application fields, such as man machine system simulation software, human reliability analysis (HRA) and expert judgement. Specific event sequences were, after the surveys, selected for application and testing of a number of ISA methods. The event sequences discussed in the report were cold overpressure of BWR, shutdown LOCA of BWR, steam generator tube rupture of a PWR and BWR disturbed signal view in the control room after an external event. Different teams analysed these sequences by using different ISA and HRA methods. Two kinds of results were obtained from the ISA project: sequence specific and more general findings. The sequence specific results are discussed together with each sequence description. The general lessons are discussed under a separate chapter by using comparisons of different case studies. These lessons include areas ranging from plant safety management (design, procedures, instrumentation, operations, maintenance and safety practices) to methodological findings (ISA methodology, PSA,HRA, physical analyses, behavioural analyses and uncertainty assessment). Finally follows a discussion about the project and conclusions are presented. An interdisciplinary study of complex phenomena is a natural way to produce valuable and innovative results. This project came up with structured ways to perform ISA and managed to apply the in practice. The project also highlighted some areas where more work is needed. In the HRA work, development is required for the use of simulators and expert judgement as

  16. Central Receiver Solar Thermal Power System, Phase 1. CDRL Item 10. Final technical progress report

    Energy Technology Data Exchange (ETDEWEB)

    Hallet, Jr., R. W.; Gervais, R. L.

    1978-05-01

    Results of analysis and design efforts by McDonnell Douglas Astronautics Company (MDAC), Rocketdyne, Stearns-Roger, Inc., Sheldahl, Inc., and the University of Houston between 1 July 1975 and 30 June 1977 are summarized. This is the Final Technical Progress Report published on the Phase 1 Central Receiver Solar Thermal Power System contract. Historical summaries and final selection of 10-MWe pilot plant and 100-MWe commercial systems are presented, with emphasis on the collector field characteristics, overall system performance, selection of steam/feedwater operating conditions, and rationale for system and subsystem selection. The commercial and pilot plant designs, as well as the subsystem research experiment activities for the collector, receiver, and thermal storage subsystems are presented, including a historical summary, design summary, and a description of the overall SRE test program and major test results for each of the subsystems.

  17. Final Progress Report: SPECT Assay of Radiolabeled Monoclonal Antibodies

    International Nuclear Information System (INIS)

    During the past project period, we proposed to collaborate closely with DOE's Thomas Jefferson National Accelerator Facility (Jefferson Lab or JLab) to design a compact, ultra-high-resolution, high-sensitivity gamma camera for quantifying brain-tumor distributions of I-131. We also proposed to continue our on-going research in developing and evaluating pinhole collimation for quantitative ultra-high-resolution imaging of I-131-labeled MAbs. We have made excellent progress in accomplishing much of the research related to pinhole collimation. Many of the most significant results have been presented in peer-reviewed journal articles and conference proceedings. We have also made good progress in collaborating with JLab's Detector Group in developing a compact, ultra-high-resolution, gamma camera. A prototype I-131 imager was delivered to Duke on May 28, 2003. Our research results are summarized in the following sections. A. JLAB-DUKE DEDICATED BRAIN-TUMOR IMAGING SYSTEM A.1. Determination of Optimal Collimator Design During the current project period a prototype I-131 dedicated brain imager has been designed and built. Computer simulations and analysis of alternate designs were performed at Duke to determine an optimal collimator design. Collimator response was characterized by spatial resolution and sensitivity. Both geometric (non-penetrative) and penetrative sensitivities were considered in selecting an optimal collimator design. Based on these simulation results, two collimator designs were selected and built by external vendors. Initial imaging results were obtained using these collimators. B. INITIAL DEVELOPMENT OF SPECT RECONSTRUCTION SOFTWARE FOR JLAB-DUKE CAMERA B.1. Modeling Thick Septa and Collimator Holes: Geometrical-Phantom Study A geometrical phantom was designed to illuminate spatial resolution effects. The phantom includes a uniformly attenuating medium that consists of all voxels within an elliptical cylinder that is centered on the axis of rotation

  18. Progress in realistic LOCA analysis

    International Nuclear Information System (INIS)

    In 1988 the USNRC revised the ECCS rule contained in Appendix K and Section 50.46 of 10 CFR Part 50, which governs the analysis of the Loss Of Coolant Accident (LOCA). The revised regulation allows the use of realistic computer models to calculate the loss of coolant accident. In addition, the new regulation allows the use of high probability estimates of peak cladding temperature (PCT), rather than upper bound estimates. Prior to this modification, the regulations were a prescriptive set of rules which defined what assumptions must be made about the plant initial conditions and how various physical processes should be modeled. The resulting analyses were highly conservative in their prediction of the performance of the ECCS, and placed tight constraints on core power distributions, ECCS set points and functional requirements, and surveillance and testing. These restrictions, if relaxed, will allow for additional economy, flexibility, and in some cases, improved reliability and safety as well. For example, additional economy and operating flexibility can be achieved by implementing several available core and fuel rod designs to increase fuel discharge burnup and reduce neutron flux on the reactor vessel. The benefits of application of best estimate methods to LOCA analyses have typically been associated with reductions in fuel costs, resulting from optimized fuel designs, or increased revenue from power upratings. Fuel cost savings are relatively easy to quantify, and have been estimated at several millions of dollars per cycle for an individual plant. Best estimate methods are also likely to contribute significantly to reductions in O and M costs, although these reductions are more difficult to quantify. Examples of O and M cost reductions are: 1) Delaying equipment replacement. With best estimate methods, LOCA is no longer a factor in limiting power levels for plants with high tube plugging levels or degraded safety injection systems. If other requirements for

  19. Verification of Steelmaking Slags Iron Content Final Technical Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    J.Y. Hwang

    2006-10-04

    The steel industry in the United States generates about 30 million tons of by-products each year, including 6 million tons of desulfurization and BOF/BOP slag. The recycling of BF (blast furnace) slag has made significant progress in past years with much of the material being utilized as construction aggregate and in cementitious applications. However, the recycling of desulfurization and BOF/BOP slags still faces many technical, economic, and environmental challenges. Previous efforts have focused on in-plant recycling of the by-products, achieving only limited success. As a result, large amounts of by-products of various qualities have been stockpiled at steel mills or disposed into landfills. After more than 50 years of stockpiling and landfilling, available mill site space has diminished and environmental constraints have increased. The prospect of conventionally landfilling of the material is a high cost option, a waste of true national resources, and an eternal material liability issue. The research effort has demonstrated that major inroads have been made in establishing the viability of recycling and reuse of the steelmaking slags. The research identified key components in the slags, developed technologies to separate the iron units and produce marketable products from the separation processes. Three products are generated from the technology developed in this research, including a high grade iron product containing about 90%Fe, a medium grade iron product containing about 60% Fe, and a low grade iron product containing less than 10% Fe. The high grade iron product contains primarily metallic iron and can be marketed as a replacement of pig iron or DRI (Direct Reduced Iron) for steel mills. The medium grade iron product contains both iron oxide and metallic iron and can be utilized as a substitute for the iron ore in the blast furnace. The low grade iron product is rich in calcium, magnesium and iron oxides and silicates. It has a sufficient lime value and

  20. Solid state NMR coal science. Final progress report

    Energy Technology Data Exchange (ETDEWEB)

    Zilm, K.W.

    1986-08-01

    This report covers the final work on this project and summarizes the accomplishments of the project. The dipolar shift correlated 2D NMR method described in previous reports has been applied to a whole coal successfully. The theory necessary for semi-quantitative interpretation of this data has also been worked out and implemented computationally. Several interesting structural features in coal seen by the 2D dipolar shift experiment not previously observed by other NMR methods are discussed. 4 figs.

  1. A Parallel Program Analysis Framework for the ACTS Toolkit; FINAL

    International Nuclear Information System (INIS)

    OAK 270 - The final report summarizes the technical progress achieved during the project. A Parallel Program Analysis Framework for the acts toolkit, referred to as the TAU project. Described are the results in four work areas: (1) creation of a performance system for integrated instrumentation, measurement, analysis and visualization. (2) development of a performance measurement system for parallel profiling and tracing (3) development of an advanced program analysis system to enable creation of source-based performance and programing tools (4) development of parallel program interaction technology for accessing, performance information and application data during execution

  2. Nuclear research with the electromagnetic probe. Final progress report

    International Nuclear Information System (INIS)

    This is the final report on the research carried at Stanford University under contract DE-FG03-88ER40439. All the work accomplished under this grant is reported in the publications listed as part of the Principal Investigator bibliography at the end of this report. In the last few years our research was directed at some of the forefront questions in nuclear physics. We investigated the nuclear medium effects on the intrinsic properties of bound nucleons, specifically the ectromagnetic form factors. For these studies we performed a number of specialized electron scattering experiments with specific sensitivity to nuclear medium effects. At the next level of structure, elementary constituents of matter are quarks and gluons. Defining the energy regime where the quark-gluon description of nuclear systems becomes more relevant than the nucleon-meson description is of great importance in thoroughly understanding the nuclear structure. To explore this transition region, we studied the scaling region in the disintegration of the deuteron, the simplest nuclear system with high energy photons. Finally we focused on the investigation of the nucleon internal spin structure along with the test of the Bjoerken sum rule a fundamental sum rule of QCD

  3. Final Progress Report for Ionospheric Dusty Plasma In the Laboratory [Smokey Plasma

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, Scott [Professor

    2010-09-28

    “Ionospheric Dusty Plasma in the Laboratory” is a research project with the purpose of finding and reproducing the characteristics of plasma in the polar mesosphere that is unusually cold (down to 140 K) and contains nanometer-sized dust particles. This final progress report summarizes results from four years of effort that include a final year with a no-cost extension.

  4. 1993 annual final progress report: July 1992 through June 1993

    Energy Technology Data Exchange (ETDEWEB)

    Rohatgi, A.; Crotty, G.; Chen, Z.; Sana, P.; Salami, J.; Doolittle, A.; Pang, A.; Pham, T. [Georgia Inst. of Tech., Atlanta, GA (United States). School of Electrical and Computer Engineering

    1994-11-01

    This is the first annual report since the Inauguration of the University Center of Excellence for Photovoltaics Research and Development (UCEP) at Georgia Tech. The essential objective of the Center is to improve the fundamental understanding of the science and technology of advanced PV devices and materials, to provide training and enrich the educational experience of students in the field, and to increase US competitiveness by providing guidelines to industry and DOE for achieving cost-effective and high efficiency PV devices. These objectives are to be accomplished through a combination of research and education. This report summarizes the technical accomplishments, including modeling, processing, and characterization of cast multicrystalline silicon solar cells; use of modeling and PCD measurements to develop a road map for progressing toward 20% multicrystalline and 25% single crystalline cells; the development of a novel PECVD SiN/SiO{sub 2} AR coating that also provides good surface passivation; PECVD deposited SiO{sub 2} films with record low S and D{sub it} at the SiO{sub 2}/Si interface; and educational activities and accomplishments.

  5. IRIS International Reactor Innovative and Secure Final Technical Progress Report

    International Nuclear Information System (INIS)

    OAK-B135 This NERI project, originally started as the Secure Transportable Autonomous Light Water Reactor (STAR-LW) and currently known as the International Reactor Innovative and Secure (IRIS) project, had the objective of investigating a novel type of water-cooled reactor to satisfy the Generation IV goals: fuel cycle sustainability, enhanced reliability and safety, and improved economics. The research objectives over the three-year (1999-2002) program were as follows: First year: Assess various design alternatives and establish main characteristics of a point design; Second year: Perform feasibility and engineering assessment of the selected design solutions; Third year: Complete reactor design and performance evaluation, including cost assessment These objectives were fully attained and actually they served to launch IRIS as a full fledged project for eventual commercial deployment. The program did not terminate in 2002 at the end of the NERI program, and has just entered in its fifth year. This has been made possible by the IRIS project participants which have grown from the original four member, two-countries team to the current twenty members, nine countries consortium. All the consortium members work under their own funding and it is estimated that the value of their in-kind contributions over the life of the project has been of the order of $30M. Currently, approximately 100 people worldwide are involved in the project. A very important constituency of the IRIS project is the academia: 7 universities from four countries are members of the consortium and five more US universities are associated via parallel NERI programs. To date, 97 students have worked or are working on IRIS; 59 IRIS-related graduate theses have been prepared or are in preparation, and 41 of these students have already graduated with M.S. (33) or Ph.D. (8) degrees. This ''final'' report (final only as far as the NERI program is concerned) summarizes the work performed in the first four

  6. Advanced Fuel Cycle Initiative University Fellowship Program. Final Progress Report

    International Nuclear Information System (INIS)

    2004-2011 Final Report for AFCI University Fellowship Program. The goal of this effort was to be supportive of university students and university programs - particularly those students and programs that will help to strengthen the development of nuclear-related fields. The program also supported the stability of the nuclear infrastructure and developed research partnerships that are helping to enlarge the national nuclear science technology base. In this fellowship program, the U.S. Department of Energy sought master's degree students in nuclear, mechanical, or chemical engineering, engineering/applied physics, physics, chemistry, radiochemistry, or fields of science and engineering applicable to the AFCI/Gen IV/GNEP missions in order to meet future U.S. nuclear program needs. The fellowship program identified candidates and selected full time students of high-caliber who were taking nuclear courses as part of their degree programs. The DOE Academic Program Managers encouraged fellows to pursue summer internships at national laboratories and supported the students with appropriate information so that both the fellows and the nation's nuclear energy objectives were successful.

  7. Non-destructive determination of trace elements. Final progress report

    International Nuclear Information System (INIS)

    In the course of this project we have successfully designed, built, and tested the first neutron beam facility dedicated to routine multielement neutron capture prompt-γ activation analysis (PGAA). This technique is capable of accurately measuring concentrations of up to 20 elements in a number of sample types, and is an extremely valuable complement to instrumental neutron activation analysis (INAA) and other analytical methods. We have found PGAA to have some major advantages over INAA: (1) the sample is subjected to neutron fluxes about five orders of magnitude less than in PGAA, with essentially no radiation or heating damage; (2) as the data are taken during sample irradiation, analyses can be performed immediately instead of waiting up to four weeks as in INAA; (3) it is capable of measuring all major elements, except oxygen, in many samples, including H, C, N, and Si, which cannot be done by INAA; and (4) it is especially sensitive for the trace elements B, Cd, Sm and Gd. In addition, we have characterized the overall capabilities of PGAA and the corrections necessary to make it an extremely accurate technique. We have applied PGAA in a number of studies in which it has proved to be extremely valuable and, at times, even providing crucial information that other techniques were incapable of supplying. 1 fig., 6 tabs

  8. An analysis of the practical part of the final apprenticeship examinations at a particular apprenticeship school

    OpenAIRE

    Chvátal, Ivan

    2013-01-01

    Bachelor thesis named "An analysis of the practical part of the final apprenticeship examinations at a particular apprenticeship school" deals with the pros and cons of final exams according to the common final examinations in the context of current labor market demands. Author compares progress and results of the practical part of final examination in regular and alternate date in 2012 in the field of secondary education of apprenticeship certificate 23-68-H/001Automechan...

  9. Final Progress Report: Internship at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Dunham, Ryan Q. [Los Alamos National Laboratory

    2012-08-10

    Originally I was tasked fluidized bed modeling, however, I changed projects. While still working with ANSYS Fluent, I performed a study of particle tracks in glove boxes. This is useful from a Health-Physics perspective, dealing respirable particles that can be hazardous to the human body. I iteratively tested different amounts of turbulent particles in a steady-state flow. The goal of this testing was to discover how Fluent handles built-in Rosin-Rammler distributions for particle injections. I worked on the health physics flow problems and distribution analysis under the direction of two mentors, Bruce Letellier and Dave Decroix. I set up and ran particle injection calculations using Fluent. I tried different combinations of input parameters to produce sets of 500,000, 1 million, and 1.5 million particles to determine what a good test case would be for future experiments. I performed a variety of tasks in my work as an Undergraduate Student Intern at LANL this summer, and learned how to use a powerful CFD application in addition to expanding my skills in MATLAB. I enjoyed my work at LANL and hope to be able to use the experience here to further my career in the future working in a security-conscious environment. My mentors provided guidance and help with all of my projects and I am grateful for the opportunity to work at Los Alamos National Laboratory.

  10. Implementing Program Integrity from an HBCU Perspective: Progress, Problems, and Prospects. An Analysis of Part H, Program Integrity - TRIAD of the Higher Education Act and the Final Rules and Related Interim Final Regulations Published in the "Federal Register" on April 29, 1994.

    Science.gov (United States)

    Blakely, William A.

    This paper examines the impact and implications for the nation's 104 historically black colleges and universities (HBCUs) of the final regulations published in the April 29, 1994 "Federal Register" and traces both the legislative and regulatory history of Part H of the Higher Education Act provisions. The analysis addresses specific issues,…

  11. Final Technical Progress Report Long term risk from actinides in the environment: Modes of mobility; FINAL

    International Nuclear Information System (INIS)

    in diameter and approximately 22 cm long. A thin ''marker layer'' of white soil was added to the top of each column followed by a thin layer of soil that had been spiked with 137Cs, cerium and lanthanum was applied to the surface. Approximately 900 cm of water (the equivalent of about 30 years of rainfall) was then applied at a rate of 3.2 L d-1. All of the activity contained in the soil core appeared to be in the top few mm of soil, i.e. there was virtually no movement of the 134Cs labeled particles. Finally, a library of object-oriented model components was created using Visual Basic to support the construction of contaminant transport models. These components greatly simplify the task of building 1- to 3- dimensional simulation models for risk assessment. The model components created under this funding were subsequently applied to help answer questions regarding risks from irrigation associated with potential releases from the Yucca Mountain waste repository

  12. 40 CFR 60.1630 - How do I comply with the increment of progress for achieving final compliance?

    Science.gov (United States)

    2010-07-01

    ... Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or... progress for achieving final compliance? For the final compliance increment of progress, you must complete two items: (a) Complete all process changes and complete retrofit construction as specified in...

  13. Factors Influencing Progressive Failure Analysis Predictions for Laminated Composite Structure

    Science.gov (United States)

    Knight, Norman F., Jr.

    2008-01-01

    Progressive failure material modeling methods used for structural analysis including failure initiation and material degradation are presented. Different failure initiation criteria and material degradation models are described that define progressive failure formulations. These progressive failure formulations are implemented in a user-defined material model for use with a nonlinear finite element analysis tool. The failure initiation criteria include the maximum stress criteria, maximum strain criteria, the Tsai-Wu failure polynomial, and the Hashin criteria. The material degradation model is based on the ply-discounting approach where the local material constitutive coefficients are degraded. Applications and extensions of the progressive failure analysis material model address two-dimensional plate and shell finite elements and three-dimensional solid finite elements. Implementation details are described in the present paper. Parametric studies for laminated composite structures are discussed to illustrate the features of the progressive failure modeling methods that have been implemented and to demonstrate their influence on progressive failure analysis predictions.

  14. Primary progressive aphasia : neuropsychological analysis and evolution

    OpenAIRE

    Maruta, Carolina Pires, 1985-

    2015-01-01

    Tese de doutoramento, Ciências Biomédicas (Neurociências), Universidade de Lisboa, Faculdade de Medicina, 2015 Frontotemporal lobar degeneration (FTLD) is the second leading cause of early-onset (< 65 years) dementia. Some of its forms may begin by isolated language deficits, which are known as Primary Progressive Aphasia (PPA). PPA is defined as the insidious onset and progressive loss of linguistic abilities in the absence of major deficits in other areas of cognition or in activities of...

  15. Additional EIPC Study Analysis. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Hadley, Stanton W [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gotham, Douglas J. [Purdue Univ., West Lafayette, IN (United States); Luciani, Ralph L. [Navigant Consultant Inc., Suwanee, GA (United States)

    2014-12-01

    Between 2010 and 2012 the Eastern Interconnection Planning Collaborative (EIPC) conducted a major long-term resource and transmission study of the Eastern Interconnection (EI). With guidance from a Stakeholder Steering Committee (SSC) that included representatives from the Eastern Interconnection States Planning Council (EISPC) among others, the project was conducted in two phases. Phase 1 involved a long-term capacity expansion analysis that involved creation of eight major futures plus 72 sensitivities. Three scenarios were selected for more extensive transmission- focused evaluation in Phase 2. Five power flow analyses, nine production cost model runs (including six sensitivities), and three capital cost estimations were developed during this second phase. The results from Phase 1 and 2 provided a wealth of data that could be examined further to address energy-related questions. A list of 14 topics was developed for further analysis. This paper brings together the earlier interim reports of the first 13 topics plus one additional topic into a single final report.

  16. Flow-induced vibration for light water reactors. Final progress report, July 1981-September 1981

    International Nuclear Information System (INIS)

    Flow-Induced Vibration for Light Water Reactors (FIV for LWRs) is a program designed to improve the FIV performance of light water reactors through the development of design criteria, analytical models for predicting behavior of components, and general scaling laws to improve the accuracy of reduced-scale tests, and through the identification of high FIV risk areas. The program is managed by the General Electric Nuclear Power Systems Engineering Department and has three major contributors: General Electric Nuclear Power Systems Engineering Department (NPSED), General Electric Corporate Research and Development (CR and D) and Argonne National Laboratory (ANL). The program commenced December 1, 1976. This progress report summarizes the accomplishments achieved during the final period from July 1981 to September 1981. This is the last quarterly progress report to be issued for this program

  17. Progress Testing: Critical Analysis and Suggested Practices

    Science.gov (United States)

    Albanese, Mark; Case, Susan M.

    2016-01-01

    Educators have long lamented the tendency of students to engage in rote memorization in preparation for tests rather than engaging in deep learning where they attempt to gain meaning from their studies. Rote memorization driven by objective exams has been termed a steering effect. Progress testing (PT), in which a comprehensive examination…

  18. Systems analysis department annual progress report 1986

    International Nuclear Information System (INIS)

    The report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1986. The activities may be classified as energy systems analysis and risk and reliability analysis. The report includes a list of staff members. (author)

  19. 40 CFR 62.15040 - What are the requirements for meeting increments of progress and achieving final compliance?

    Science.gov (United States)

    2010-07-01

    ... Combustion Units Constructed on or Before August 30, 1999 Compliance Schedule and Increments of Progress § 62.... (3) Initiate onsite construction. (4) Complete onsite construction. (5) Achieve final compliance....

  20. Risk Analysis Group annual progress report 1984

    International Nuclear Information System (INIS)

    The activities of the Risk Analysis Group at Risoe during 1984 are presented. These include descriptions in some detail of work on general development topics and risk analysis performed as contractor. (author)

  1. Progressive Damage Analysis of Bonded Composite Joints

    Science.gov (United States)

    Leone, Frank A., Jr.; Girolamo, Donato; Davila, Carlos G.

    2012-01-01

    The present work is related to the development and application of progressive damage modeling techniques to bonded joint technology. The joint designs studied in this work include a conventional composite splice joint and a NASA-patented durable redundant joint. Both designs involve honeycomb sandwich structures with carbon/epoxy facesheets joined using adhesively bonded doublers.Progressive damage modeling allows for the prediction of the initiation and evolution of damage within a structure. For structures that include multiple material systems, such as the joint designs under consideration, the number of potential failure mechanisms that must be accounted for drastically increases the complexity of the analyses. Potential failure mechanisms include fiber fracture, intraply matrix cracking, delamination, core crushing, adhesive failure, and their interactions. The bonded joints were modeled using highly parametric, explicitly solved finite element models, with damage modeling implemented via custom user-written subroutines. Each ply was discretely meshed using three-dimensional solid elements. Layers of cohesive elements were included between each ply to account for the possibility of delaminations and were used to model the adhesive layers forming the joint. Good correlation with experimental results was achieved both in terms of load-displacement history and the predicted failure mechanism(s).

  2. Systems Analysis Department annual progress report 1998

    DEFF Research Database (Denmark)

    1999-01-01

    The report describes the work of the Systems Analysis Department at Risø National Laboratory during 1998. The department undertakes research within Energy Systems Analysis, Integrated Energy, Environment and Development Planning - UNEP Centre, IndustrialSafety and Reliability, Man/Machine Interac......The report describes the work of the Systems Analysis Department at Risø National Laboratory during 1998. The department undertakes research within Energy Systems Analysis, Integrated Energy, Environment and Development Planning - UNEP Centre, IndustrialSafety and Reliability, Man...

  3. Systems Analysis Department annual progress report 1999

    DEFF Research Database (Denmark)

    2000-01-01

    This report describes the work of the Systems Analysis Department at Risø National Laboratory during 1999. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning - UNEP Centre, Safety,Realiability and Human Factors, and Technology...

  4. Systems Analysis Department annual progress report 1998

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Hans; Olsson, Charlotte; Loevborg, Leif [eds.

    1999-03-01

    The report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1998. The department undertakes research within Energy Systems Analysis, Integrated Energy, Environment and Development Planning - UNEP Centre, Industrial Safety and Reliability, Man/Machine Interaction and Technology Scenarios. The report includes lists of publications, lectures, committees and staff members. (au) 111 refs.

  5. Systems Analysis Department. Annual Progress Report 1999

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Hans; Olsson, Charlotte; Loevborg, Leif [eds.

    2000-03-01

    This report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1999. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning-UNEP Centre, Safety, Reliability and Human Factors, and Technology Scenarios. The report includes summary statistics and lists of publications, committees and staff members. (au)

  6. Systems Analysis department. Annual progress report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Hans; Olsson, Charlotte; Petersen, Kurt E.

    1998-03-01

    The report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1997. The department is undertaking research within Energy systems Analysis, Integrated Energy, Environment and Development Planning - UNEP Centre, Industrial Safety and Reliability and Man/Machine Interaction. The report includes lists of publications lectures, committees and staff members. (au) 110 refs.

  7. Progress report on the AMT analysis

    International Nuclear Information System (INIS)

    ICF Resources Incorporated's analysis of the Alternative Minimum Tax (AMT) has examined its effect on the US oil and gas industry from several different perspectives, to estimate the effect of the three relief proposals and to better understand the source of the outcry about the AMTs ''inequities.'' This report is a brief summary of the methodology and results to date. The complexity of the accounting mechanisms that comprise the AMT and the disparity between this analytical conclusions and clauses made by the oil and gas industry (principally the IPAA) have led this analysis through several distinct phases of: Project-level analysis; firm-level analysis; and demographic analysis. These analyses are described in detail

  8. The latest progress of fission track analysis

    International Nuclear Information System (INIS)

    Fission track analysis as a new nuclear track technique is based on fission track annealing in mineral and is used for oil and gas exploration successfully. The west part of China is the main exploration for oil and gas. The oil and gas basins there experienced much more complicated thermal history and higher paleotemperature. In order to apply fission track analysis to these basins, following work was be carried out: 1. The decomposition of grain age distribution of zircon fission tracks. 2. Study on thermal history of Ordos basin using zircon fission track analysis. 3. The fission track study on the Qiang Tang basin in tibet

  9. Site safety progress review of spent fuel central interim storage facility. Final report

    International Nuclear Information System (INIS)

    Following the request of the Czech Power Board (CEZ) and within the scope of the Technical Cooperation Project CZR/9/003, a progress review of the site safety of the Spent Fuel Central Interim Storage Facility (SFCISF) was performed. The review involved the first two stages of the works comprising the regional survey and identification of candidate sites for the underground and surface storage options. Five sites have been identified as a result of the previous works. The following two stages will involved the identification of the preferred candidate sites for the two options and the final site qualification. The present review had the purpose of assessing the work already performed and making recommendations for the next two stages of works

  10. Systems Analysis Department. Annual progress report 1996

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, H.; Olsson, C.; Petersen, K.E. [eds.

    1997-03-01

    The report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1996. The department is undertaking research within Simulation and Optimisation of Energy Systems, Energy and Environment in Developing Countries - UNEP Centre, Integrated Environmental and Risk Management and Man/Machine Interaction. The report includes lists of publications, lectures, committees and staff members. (au) 131 refs.

  11. The Independent Technical Analysis Process Final Report 2006-2007.

    Energy Technology Data Exchange (ETDEWEB)

    Duberstein, Corey; Ham, Kenneth; Dauble, Dennis; Johnson, Gary [Pacific Northwest National Laboratory

    2007-03-01

    The Bonneville Power Administration (BPA) contracted with the Pacific Northwest National Laboratory (PNNL) to provide technical analytical support for system-wide fish passage information (BPA Project No. 2006-010-00). The goal of this project was to produce rigorous technical analysis products using independent analysts and anonymous peer reviewers. This project provided an independent technical source for non-routine fish passage analyses while allowing routine support functions to be performed by other well-qualified entities. The Independent Technical Analysis Process (ITAP) was created to provide non-routine analysis for fish and wildlife agencies and tribes in particular and the public in general on matters related to juvenile and adult salmon and steelhead passage through the mainstem hydrosystem. The process was designed to maintain the independence of analysts and reviewers from parties requesting analyses, to avoid potential bias in technical products. The objectives identified for this project were to administer a rigorous, transparent process to deliver unbiased technical assistance necessary to coordinate recommendations for storage reservoir and river operations that avoid potential conflicts between anadromous and resident fish. Seven work elements, designated by numbered categories in the Pisces project tracking system, were created to define and accomplish project goals as follows: (1) 118 Coordination - Coordinate technical analysis and review process: (a) Retain expertise for analyst/reviewer roles. (b) Draft research directives. (c) Send directive to the analyst. (d) Coordinate two independent reviews of the draft report. (e) Ensure reviewer comments are addressed within the final report. (2) 162 Analyze/Interpret Data - Implement the independent aspects of the project. (3) 122 Provide Technical Review - Implement the review process for the analysts. (4) 132 Produce Annual Report - FY06 annual progress report with Pisces Disseminate (5) 161

  12. Dynamics and vibrations progress in nonlinear analysis

    CERN Document Server

    Kachapi, Seyed Habibollah Hashemi

    2014-01-01

    Dynamical and vibratory systems are basically an application of mathematics and applied sciences to the solution of real world problems. Before being able to solve real world problems, it is necessary to carefully study dynamical and vibratory systems and solve all available problems in case of linear and nonlinear equations using analytical and numerical methods. It is of great importance to study nonlinearity in dynamics and vibration; because almost all applied processes act nonlinearly, and on the other hand, nonlinear analysis of complex systems is one of the most important and complicated tasks, especially in engineering and applied sciences problems. There are probably a handful of books on nonlinear dynamics and vibrations analysis. Some of these books are written at a fundamental level that may not meet ambitious engineering program requirements. Others are specialized in certain fields of oscillatory systems, including modeling and simulations. In this book, we attempt to strike a balance between th...

  13. Progress on the CWU READI Analysis Center

    Science.gov (United States)

    Melbourne, T. I.; Szeliga, W. M.; Santillan, V. M.; Scrivner, C.

    2015-12-01

    Real-time GPS position streams are desirable for a variety of seismic monitoring and hazard mitigation applications. We report on progress in our development of a comprehensive real-time GPS-based seismic monitoring system for the Cascadia subduction zone. This system is based on 1 Hz point position estimates computed in the ITRF08 reference frame. Convergence from phase and range observables to point position estimates is accelerated using a Kalman filter based, on-line stream editor that produces independent estimations of carrier phase integer biases and other parameters. Positions are then estimated using a short-arc approach and algorithms from JPL's GIPSY-OASIS software with satellite clock and orbit products from the International GNSS Service (IGS). The resulting positions show typical RMS scatter of 2.5 cm in the horizontal and 5 cm in the vertical with latencies below 2 seconds. To facilitate the use of these point position streams for applications such as seismic monitoring, we broadcast real-time positions and covariances using custom-built aggregation-distribution software based on RabbitMQ messaging platform. This software is capable of buffering 24-hour streams for hundreds of stations and providing them through a REST-ful web interface. To demonstrate the power of this approach, we have developed a Java-based front-end that provides a real-time visual display of time-series, displacement vector fields, and map-view, contoured, peak ground displacement. This Java-based front-end is available for download through the PANGA website. We are currently analyzing 80 PBO and PANGA stations along the Cascadia margin and gearing up to process all 400+ real-time stations that are operating in the Pacific Northwest, many of which are currently telemetered in real-time to CWU. These will serve as milestones towards our over-arching goal of extending our processing to include all of the available real-time streams from the Pacific rim. In addition, we have

  14. Progress in computer vision and image analysis

    CERN Document Server

    Bunke, Horst; Sánchez, Gemma; Otazu, Xavier

    2009-01-01

    This book is a collection of scientific papers published during the last five years, showing a broad spectrum of actual research topics and techniques used to solve challenging problems in the areas of computer vision and image analysis. The book will appeal to researchers, technicians and graduate students. Sample Chapter(s). Chapter 1: An Appearance-Based Method for Parametric Video Registration (2,352 KB). Contents: An Appearance-Based Method for Parametric Video Registration (X Orriols et al.); Relevance of Multifractal Textures in Static Images (A Turiel); Potential Fields as an External

  15. Bedded-salt repository analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Guiffre, M.S.; Kaplan, M.F.; Ensminger, D.A.; Oston, S.G.; Nalbandian, J.Y.

    1980-03-31

    This report contains a description of an analysis of generic nuclear waste repository in bedded salt. This analysis was performed by TASC for inclusion in a major Lawrence Livermore Laboratory report to NRC; this report therefore should be viewed as providing more complete and detailed information about this analysis than was possible to include in the LLL report. The analysis is performed with the NUTRAN computer codes which are described in the report. The model to be analyzed is defined, and the results of a series of possible waste migration scenarios are presented. Several of these scenarios are used as the basis for a sensitivity analysis, and an uncertainty analysis utilizing Monte Carlo techniques is also performed. A new method for defining the consequences to users of a well drilled near the repository is also described, and results are presented based on two of the waste migration scenarios.

  16. Bedded-salt repository analysis. Final report

    International Nuclear Information System (INIS)

    This report contains a description of an analysis of generic nuclear waste repository in bedded salt. This analysis was performed by TASC for inclusion in a major Lawrence Livermore Laboratory report to NRC; this report therefore should be viewed as providing more complete and detailed information about this analysis than was possible to include in the LLL report. The analysis is performed with the NUTRAN computer codes which are described in the report. The model to be analyzed is defined, and the results of a series of possible waste migration scenarios are presented. Several of these scenarios are used as the basis for a sensitivity analysis, and an uncertainty analysis utilizing Monte Carlo techniques is also performed. A new method for defining the consequences to users of a well drilled near the repository is also described, and results are presented based on two of the waste migration scenarios

  17. Safeguards information analysis: Progress, challenges and solutions

    International Nuclear Information System (INIS)

    While the IAEA's authority to verify the correctness and completeness of a State's declarations under its comprehensive safeguards agreement derives from the agreement itself, it is only with the provisions for broader access to information and locations available under an additional protocol that the IAEA is able to draw the safeguards conclusion regarding the absence of undeclared nuclear material and activities in the State. Under the State level concept, all relevant information about a State's nuclear activities is assessed to obtain as complete a picture as possible of the State's current and planned nuclear programme. The array of sources for information evaluation is both broad and diverse. Mainly, it encompasses information provided by States, information obtained from open sources, commercial satellite imagery, and inspectors' measurements. All the information is checked for internal consistency and consistency with information gathered during inspections and visits in the field. The 'information driven' approach has required an expansion of knowledge, expertise, information and analytical/evaluation skills. As the IAEA's corporate knowledge in exploiting new types of information has increased, so too has its capability for detecting proliferation indicators. In all areas concerned (open source, satellite imagery, consistency and trend analysis, nuclear trade analysis, environmental sampling, as well as State-declared information) remarkable improvements have been made with regard to methodologies, tools, expertise and skills. Although each of these areas has proven invaluable for the detection of certain undeclared activities/material, it is obvious that the strength of these methods is in their integration. Further qualitative and quantitative improvements will require the acquisition of additional specialist expertise, knowledge and technologies. The combination of all (new) technologies will be important for enhancing the IAEA's ability to detect

  18. Organic analysis progress report FY 1997

    Energy Technology Data Exchange (ETDEWEB)

    Clauss, S.A.; Grant, K.E.; Hoopes, V.; Mong, G.M.; Steele, R.; Bellofatto, D.; Sharma, A.

    1998-04-01

    The Organic Analysis and Methods Development Task is being conducted by Pacific Northwest National Laboratory (PNNL) as part of the Organic Tank Waste Safety Project. The objective of the task is to apply developed analytical methods to identify and/or quantify the amount of particular organic species in tank wastes. In addition, this task provides analytical support for the Gas Generation Studies Task, Waste Aging, and Solubility Studies. This report presents the results from analyses of tank waste samples archived at Pacific Northwest National Laboratory (PNNL) and received from the Project Hanford Management Contractor (PHMC), which included samples associated with both the Flammable Gas and Organic Tank Waste Safety Programs. The data are discussed in Section 2.0. In addition, the results of analytical support for analyzing (1) simulated wastes for Waste Aging, (2) tank waste samples for Gas Generation, and (3) simulated wastes associated with solubility studies discussed in Sections 3.0, 4.0, and 5.0, respectively. The latter part of FY 1997 was devoted to documenting the analytical procedures, including derivation gas chromatography/mass spectrometry (GC/MS) and GC/FID for quantitation, ion-pair chromatography (IPC), IC, and the cation exchange procedure for reducing the radioactivity of samples. The documentation of analytical procedures is included here and discussed in Section 6.0 and Section 7.0 discusses other analytical procedures. The references are listed in Section 8.0 and future plans are discussed in Section 9.0. Appendix A is a preprint of a manuscript accepted for publication. Appendix B contains the cc mail messages and chain-of-custody forms for the samples received for analyses. Appendix C contains the test plan for analysis of tank waste samples.

  19. Organic analysis progress report FY 1997

    International Nuclear Information System (INIS)

    The Organic Analysis and Methods Development Task is being conducted by Pacific Northwest National Laboratory (PNNL) as part of the Organic Tank Waste Safety Project. The objective of the task is to apply developed analytical methods to identify and/or quantify the amount of particular organic species in tank wastes. In addition, this task provides analytical support for the Gas Generation Studies Task, Waste Aging, and Solubility Studies. This report presents the results from analyses of tank waste samples archived at Pacific Northwest National Laboratory (PNNL) and received from the Project Hanford Management Contractor (PHMC), which included samples associated with both the Flammable Gas and Organic Tank Waste Safety Programs. The data are discussed in Section 2.0. In addition, the results of analytical support for analyzing (1) simulated wastes for Waste Aging, (2) tank waste samples for Gas Generation, and (3) simulated wastes associated with solubility studies discussed in Sections 3.0, 4.0, and 5.0, respectively. The latter part of FY 1997 was devoted to documenting the analytical procedures, including derivation gas chromatography/mass spectrometry (GC/MS) and GC/FID for quantitation, ion-pair chromatography (IPC), IC, and the cation exchange procedure for reducing the radioactivity of samples. The documentation of analytical procedures is included here and discussed in Section 6.0 and Section 7.0 discusses other analytical procedures. The references are listed in Section 8.0 and future plans are discussed in Section 9.0. Appendix A is a preprint of a manuscript accepted for publication. Appendix B contains the cc mail messages and chain-of-custody forms for the samples received for analyses. Appendix C contains the test plan for analysis of tank waste samples

  20. Risk factors for progressive ischemic stroke A retrospective analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    BACKGROUND: Progressive ischemic stroke has higher fatality rate and disability rate than common cerebral infarction, thus it is very significant to investigate the early predicting factors related to the occurrence of progressive ischemic stroke, thc potential pathological mechanism and the risk factors of early intervention for preventing the occurrence of progressive ischemic stroke and ameliorating its outcome.OBJECTIVE: To analyze the possible related risk factors in patients with progressive ishcemic stroke, so as to provide reference for the prevention and treatment of progressive ishcemic stroke.DESIGN: A retrospective analysis.SETTING: Department of Neurology, General Hospital of Beijing Coal Mining Group.PARTICIPANTS: Totally 280 patients with progressive ischemic stroke were selected from the Department of Neurology, General Hospital of Beijing Coal Mining Group from March 2002 to June 2006, including 192 males and 88 females, with a mean age of (62±7) years old. They were all accorded with the diagnostic standards for cerebral infarction set by the Fourth National Academic Meeting for Cerebrovascular Disease in 1995, and confired by CT or MRI, admitted within 24 hours after attack, and the neurological defect progressed gradually or aggravated in gradients within 72 hours after attack, and the aggravation of neurological defect was defined as the neurological deficit score decreased by more than 2 points. Meanwhile,200 inpatients with non-progressive ischemic stroke (135 males and 65 females) were selected as the control group.METHODS: After admission, a univariate analysis of variance was conducted using the factors of blood pressure, history of diabetes mellitus, fever, leukocytosis, levels of blood lipids, fibrinogen, blood glucose and plasma homocysteine, cerebral arterial stenosis, and CT symptoms of early infarction, and the significant factors were involved in the multivariate non-conditional Logistic regression analysis.MAIN OUTCOME MEASURES

  1. Errors of DWPF frit analysis: Final report

    International Nuclear Information System (INIS)

    Glass frit will be a major raw material for the operation of the Defense Waste Processing Facility. The frit will be controlled by certificate of conformance and a confirmatory analysis from a commercial analytical laboratory. The following effort provides additional quantitative information on the variability of frit chemical analyses at two commercial laboratories. Identical samples of IDMS Frit 202 were chemically analyzed at two commercial laboratories and at three different times over a period of four months. The SRL-ADS analyses, after correction with the reference standard and normalization, provided confirmatory information, but did not detect the low silica level in one of the frit samples. A methodology utilizing elliptical limits for confirming the certificate of conformance or confirmatory analysis was introduced and recommended for use when the analysis values are close but not within the specification limits. It was also suggested that the lithia specification limits might be reduced as long as CELS is used to confirm the analysis

  2. 40 CFR 62.15065 - How do I comply with the increment of progress for submittal of a final control plan?

    Science.gov (United States)

    2010-07-01

    ... Combustion Units Constructed on or Before August 30, 1999 Compliance Schedule and Increments of Progress § 62... final control plan increment of progress, you must complete two items: (a) Submit the final control plan... combustion unit's combustion capacity to less than 35 tons per day by the final compliance date, see §...

  3. Applied Behavior Analysis Is a Science And, Therefore, Progressive

    Science.gov (United States)

    Leaf, Justin B.; Leaf, Ronald; McEachin, John; Taubman, Mitchell; Ala'i-Rosales, Shahla; Ross, Robert K.; Smith, Tristram; Weiss, Mary Jane

    2016-01-01

    Applied behavior analysis (ABA) is a science and, therefore, involves progressive approaches and outcomes. In this commentary we argue that the spirit and the method of science should be maintained in order to avoid reductionist procedures, stifled innovation, and rote, unresponsive protocols that become increasingly removed from meaningful…

  4. Cold vacuum drying facility final hazard analysis report

    Energy Technology Data Exchange (ETDEWEB)

    POWERS, T.B.

    1999-06-07

    This report describes the methodology used in conducting the Cold Vacuum Dlying Facility (CVDF) Hazard Analysis to support the CVDF Final Safety Analysis Report and documents the results. The hazard analysis was performed in accordance with DOE-STD-3009-94, ''Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports,'' and implements the requirements of DOE Order 5480.23, ''Nuclear Safety Analysis Reports.''

  5. Cold vacuum drying facility final hazard analysis report

    International Nuclear Information System (INIS)

    This report describes the methodology used in conducting the Cold Vacuum Dlying Facility (CVDF) Hazard Analysis to support the CVDF Final Safety Analysis Report and documents the results. The hazard analysis was performed in accordance with DOE-STD-3009-94, ''Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports,'' and implements the requirements of DOE Order 5480.23, ''Nuclear Safety Analysis Reports.''

  6. Cold Vacuum Drying (CVD) Facility Final Hazard Analysis Report

    International Nuclear Information System (INIS)

    This report describes the methodology used in conducting the Cold Vacuum Drying Facility (CVDF) hazard Analysis to support the CVDF Final Safety Analysis Report and documents the results. The hazard analysis was performed in accordance with DOE-STD-3009-94, ''Preparation Guide for US. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports,'' and implements the requirements of DOE Order 5480.23, ''Nuclear Safety Analysis Reports.''

  7. Central receiver solar thermal power system, Phase 1. Quarterly progress report (final) for period ending March 31, 1976

    Energy Technology Data Exchange (ETDEWEB)

    None

    1976-10-01

    During this period (January 1976 through March 1976), the primary program effort was expended toward the completion of the detail design of the three major research experiments. Also, the Preliminary Pilot Plant Economic Cost Study was completed. In the Collector Subsystem, the designs for both the twenty-five mirror and the nine-mirror heliostats were completed and released. In the Receiver Subsystem, Foster Wheeler continued with the detail design of the 5 MW research experiment receiver. A preliminary draft of the detailed test plan for the receiver subsystem research experiment was prepared and is now undergoing a final review. The detailed design of the Thermal Storage Subsystem continued at Georgia Institute of Technology. Several incremental detail design reviews were held as the design progressed. During this period, Bechtel completed the preliminary environmental analysis for the Pilot Plant. The optimization studies of the electrical power generation subsystem were initiated. A major effort was the preparation of the preliminary cost analysis for the 10 MWe Central Receiver Solar Thermal Pilot Plant. This task required the development of a cost accounting structure and a definition of all of the costs associated with the design, construction, checkout, and two-year test of the Pilot Plant. (WDM)

  8. Final Technical Progress Report: Development of Low-Cost Suspension Heliostat; December 7, 2011 - December 6, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Bender, W.

    2013-01-01

    Final technical progress report of SunShot Incubator Solaflect Energy. The project succeeded in demonstrating that the Solaflect Suspension Heliostat design is viable for large-scale CSP installations. Canting accuracy is acceptable and is continually improving as Solaflect improves its understanding of this design. Cost reduction initiatives were successful, and there are still many opportunities for further development and further cost reduction.

  9. 40 CFR 62.15085 - How do I comply with the increment of progress for achieving final compliance?

    Science.gov (United States)

    2010-07-01

    ... municipal waste combustion unit identified in the final control plan and complete process changes to the... DESIGNATED FACILITIES AND POLLUTANTS Federal Plan Requirements for Small Municipal Waste Combustion Units... of progress, you must complete two items: (a) Complete all process changes and complete...

  10. TMI-2 analysis exercise. Final report

    International Nuclear Information System (INIS)

    On March 28, 1979 an accident at the Three Mile Island Unit 2 (TMI-2) nuclear power plant led to a melting of approximately 50% of the reactor's core. Since severe accidents cannot be simulated at or near full scale, TMI-2 provides a unique opportunity to assess the capability of current severe accident analysis methods to simulate an accident in a full scale nuclear power plant. In this regard the OECD Nuclear Energy Agency (NEA) in collaboration with the US Department of Energy (DOE), has established a Joint Task Group to analyze various periods of the accident in an effort to benchmark severe accident computer codes. Participants in the analysis exercise and contributors to this report are presented; the results and conclusions that may be drawn from these results of the benchmark analyses are documented in the report. Brief descriptions of the codes are included in the participant's submittals reproduced in the appendices

  11. Final report on the Pathway Analysis Task

    Energy Technology Data Exchange (ETDEWEB)

    Whicker, F.W.; Kirchner, T.B. [Colorado State Univ., Fort Collins, CO (United States)

    1993-04-01

    The Pathway Analysis Task constituted one of several multi-laboratory efforts to estimate radiation doses to people, considering all important pathways of exposure, from the testing of nuclear devices at the Nevada Test Site (NTS). The primary goal of the Pathway Analysis Task was to predict radionuclide ingestion by residents of Utah, Nevada, and portions of seven other adjoining western states following radioactive fallout deposition from individual events at the NTS. This report provides comprehensive documentation of the activities and accomplishments of Colorado State University`s Pathway Analysis Task during the entire period of support (1979--91). The history of the project will be summarized, indicating the principal dates and milestones, personnel involved, subcontractors, and budget information. Accomplishments, both primary and auxiliary, will be summarized with general results rather than technical details being emphasized. This will also serve as a guide to the reports and open literature publications produced, where the methodological details and specific results are documented. Selected examples of results on internal dose estimates are provided in this report because the data have not been published elsewhere.

  12. Final report on the Pathway Analysis Task

    International Nuclear Information System (INIS)

    The Pathway Analysis Task constituted one of several multi-laboratory efforts to estimate radiation doses to people, considering all important pathways of exposure, from the testing of nuclear devices at the Nevada Test Site (NTS). The primary goal of the Pathway Analysis Task was to predict radionuclide ingestion by residents of Utah, Nevada, and portions of seven other adjoining western states following radioactive fallout deposition from individual events at the NTS. This report provides comprehensive documentation of the activities and accomplishments of Colorado State University's Pathway Analysis Task during the entire period of support (1979--91). The history of the project will be summarized, indicating the principal dates and milestones, personnel involved, subcontractors, and budget information. Accomplishments, both primary and auxiliary, will be summarized with general results rather than technical details being emphasized. This will also serve as a guide to the reports and open literature publications produced, where the methodological details and specific results are documented. Selected examples of results on internal dose estimates are provided in this report because the data have not been published elsewhere

  13. Rankine bottoming cycle safety analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lewandowski, G.A.

    1980-02-01

    Vector Engineering Inc. conducted a safety and hazards analysis of three Rankine Bottoming Cycle Systems in public utility applications: a Thermo Electron system using Fluorinal-85 (a mixture of 85 mole % trifluoroethanol and 15 mole % water) as the working fluid; a Sundstrand system using toluene as the working fluid; and a Mechanical Technology system using steam and Freon-II as the working fluids. The properties of the working fluids considered are flammability, toxicity, and degradation, and the risks to both plant workers and the community at large are analyzed.

  14. Regulatory analysis technical evaluation handbook. Final report

    International Nuclear Information System (INIS)

    The purpose of this Handbook is to provide guidance to the regulatory analyst to promote preparation of quality regulatory analysis documents and to implement the policies of the Regulatory Analysis Guidelines of the US Nuclear Regulatory Commission (NUREG/BR-0058 Rev. 2). This Handbook expands upon policy concepts included in the NRC Guidelines and translates the six steps in preparing regulatory analyses into implementable methodologies for the analyst. It provides standardized methods of preparation and presentation of regulatory analyses, with the inclusion of input that will satisfy all backfit requirements and requirements of NRC's Committee to Review Generic Requirements. Information on the objectives of the safety goal evaluation process and potential data sources for preparing a safety goal evaluation is also included. Consistent application of the methods provided here will result in more directly comparable analyses, thus aiding decision-makers in evaluating and comparing various regulatory actions. The handbook is being issued in loose-leaf format to facilitate revisions. NRC intends to periodically revise the handbook as new and improved guidance, data, and methods become available

  15. Regulatory analysis technical evaluation handbook. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The purpose of this Handbook is to provide guidance to the regulatory analyst to promote preparation of quality regulatory analysis documents and to implement the policies of the Regulatory Analysis Guidelines of the US Nuclear Regulatory Commission (NUREG/BR-0058 Rev. 2). This Handbook expands upon policy concepts included in the NRC Guidelines and translates the six steps in preparing regulatory analyses into implementable methodologies for the analyst. It provides standardized methods of preparation and presentation of regulatory analyses, with the inclusion of input that will satisfy all backfit requirements and requirements of NRC`s Committee to Review Generic Requirements. Information on the objectives of the safety goal evaluation process and potential data sources for preparing a safety goal evaluation is also included. Consistent application of the methods provided here will result in more directly comparable analyses, thus aiding decision-makers in evaluating and comparing various regulatory actions. The handbook is being issued in loose-leaf format to facilitate revisions. NRC intends to periodically revise the handbook as new and improved guidance, data, and methods become available.

  16. Improved methods for water shutoff. Final technical progress report, October 1, 1997--September 30, 1998

    Energy Technology Data Exchange (ETDEWEB)

    Seright, R.S.; Liang, J.T.; Schrader, R.; Hagstrom, J. II; Liu, J.; Wavrik, K.

    1998-10-01

    In the United States, more than 20 billion barrels of salt water are produced each year during oilfield operations. A tremendous economic incentive exists to reduce water production if that can be accomplished without significantly sacrificing hydrocarbon production. This three-year research project had three objectives. The first objective was to identify chemical blocking agents that will (a) during placement, flow readily through fractures without penetrating significantly into porous rock and with screening out or developing excessive pressure gradients and (b) at a predictable and controllable time, become immobile and resistant breakdown upon exposure to moderate to high pressure gradients. The second objective was to identify schemes that optimize placement of the above blocking agents. The third objective was to explain why gels and other chemical blocking agents reduce permeability to one phase (e.g., water) more than that to another phase (e.g., oil or gas). The authors also wanted to identify conditions that maximize this phenomenon. This project consisted of three tasks, each of which addressed one of the above objectives. This report describes work performed during the third and final period of the project. During this three-year project, they: (1) Developed a procedure and software for sizing gelant treatments in hydraulically fractured production wells; (2) Developed a method (based on interwell tracer results) to determine the potential for applying gel treatments in naturally fractured reservoirs; (3) Characterized gel properties during extrusion through fractures; (4) Developed a method to predict gel placement in naturally fractured reservoirs; (5) Made progress in elucidating the mechanism for why some gels can reduce permeability to water more than that to oil; (6) Demonstrated the limitations of using water/oil ratio diagnostic plots to distinguish between channeling and coning; and (7) Proposed a philosophy for diagnosing and attacking water

  17. Biologic considerations in anatomic imaging with radionuclides. Final progress report, July 1974--June 1975

    International Nuclear Information System (INIS)

    An important task relating to anatomic imaging with radionuclides is the determination of factors which effect the use of imaging procedures. This is important to reduce radiation exposure in the population, to improve the efficacy of diagnostic imaging procedures and finally to provide a basis for evaluating the potential effects of proposed regulation of use rates. In this report we describe a methodology for obtaining clinical data relating to the use of the brain scan in an inner city teaching hospital. The development of a questionnaire suitable for use in a clinical setting and providing both prospective and retrospective data is presented. The results of the use of the questionnaire at the Johns Hopkins Hospital during a three month period in 1974 are shown and discussed. Some preliminary results from these data are given and a method for further analysis is indicated

  18. Post Buckling Progressive Failure Analysis of Composite Laminated Stiffened Panels

    Science.gov (United States)

    Anyfantis, Konstantinos N.; Tsouvalis, Nicholas G.

    2012-06-01

    The present work deals with the numerical prediction of the post buckling progressive and final failure response of stiffened composite panels based on structural nonlinear finite element methods. For this purpose, a progressive failure model (PFM) is developed and applied to predict the behaviour of an experimentally tested blade-stiffened panel found in the literature. Failure initiation and propagation is calculated, owing to the accumulation of the intralaminar failure modes induced in fibre reinforced composite materials. Hashin failure criteria have been employed in order to address the fiber and matrix failure modes in compression and tension. On the other hand, the Tsai-Wu failure criterion has been utilized for addressing shear failure. Failure detection is followed with the introduction of corresponding material degradation rules depending on the individual failure mechanisms. Failure initiation and failure propagation as well as the post buckling ultimate attained load have been numerically evaluated. Final failure behaviour of the simulated stiffened panel is due to sudden global failure, as concluded from comparisons between numerical and experimental results being in good agreement.

  19. High-Efficiency Nitride-Based Solid-State Lighting. Final Technical Progress Report

    International Nuclear Information System (INIS)

    In this final technical progress report we summarize research accomplished during Department of Energy contract DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. Two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and the Lighting Research Center at Rensselaer Polytechnic Institute (led by Dr. N. Narendran), pursued the goals of this contract from thin film growth, characterization, and packaging/luminaire design standpoints. The UCSB team initially pursued the development of blue gallium nitride (GaN)-based vertical-cavity surface-emitting lasers, as well as ultraviolet GaN-based light emitting diodes (LEDs). In Year 2, the emphasis shifted to resonant-cavity light emitting diodes, also known as micro-cavity LEDs when extremely thin device cavities are fabricated. These devices have very directional emission and higher light extraction efficiency than conventional LEDs. Via the optimization of thin-film growth and refinement of device processing, we decreased the total cavity thickness to less than 1 (micro)m, such that micro-cavity effects were clearly observed and a light extraction efficiency of over 10% was reached. We also began the development of photonic crystals for increased light extraction, in particular for so-called ''guided modes'' which would otherwise propagate laterally in the device and be re-absorbed. Finally, we pursued the growth of smooth, high-quality nonpolar a-plane and m-plane GaN films, as well as blue light emitting diodes on these novel films. Initial nonpolar LEDs showed the expected behavior of negligible peak wavelength shift with increasing drive current. M-plane LEDs in particular show promise, as unpackaged devices had unsaturated optical output power of ∼ 3 mW at 200 mA drive current. The LRC's tasks were aimed at developing the subcomponents necessary for packaging UCSB's light emitting diodes, and packaging them to produce a white light

  20. Analysis Methods for Progressive Damage of Composite Structures

    Science.gov (United States)

    Rose, Cheryl A.; Davila, Carlos G.; Leone, Frank A.

    2013-01-01

    This document provides an overview of recent accomplishments and lessons learned in the development of general progressive damage analysis methods for predicting the residual strength and life of composite structures. These developments are described within their State-of-the-Art (SoA) context and the associated technology barriers. The emphasis of the authors is on developing these analysis tools for application at the structural level. Hence, modeling of damage progression is undertaken at the mesoscale, where the plies of a laminate are represented as a homogenous orthotropic continuum. The aim of the present effort is establish the ranges of validity of available models, to identify technology barriers, and to establish the foundations of the future investigation efforts. Such are the necessary steps towards accurate and robust simulations that can replace some of the expensive and time-consuming "building block" tests that are currently required for the design and certification of aerospace structures.

  1. Final Progress Report: Isotope Identification Algorithm for Rapid and Accurate Determination of Radioisotopes Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Rawool-Sullivan, Mohini [Los Alamos National Laboratory; Bounds, John Alan [Los Alamos National Laboratory; Brumby, Steven P. [Los Alamos National Laboratory; Prasad, Lakshman [Los Alamos National Laboratory; Sullivan, John P. [Los Alamos National Laboratory

    2012-04-30

    This is the final report of the project titled, 'Isotope Identification Algorithm for Rapid and Accurate Determination of Radioisotopes,' PMIS project number LA10-HUMANID-PD03. The goal of the work was to demonstrate principles of emulating a human analysis approach towards the data collected using radiation isotope identification devices (RIIDs). It summarizes work performed over the FY10 time period. The goal of the work was to demonstrate principles of emulating a human analysis approach towards the data collected using radiation isotope identification devices (RIIDs). Human analysts begin analyzing a spectrum based on features in the spectrum - lines and shapes that are present in a given spectrum. The proposed work was to carry out a feasibility study that will pick out all gamma ray peaks and other features such as Compton edges, bremsstrahlung, presence/absence of shielding and presence of neutrons and escape peaks. Ultimately success of this feasibility study will allow us to collectively explain identified features and form a realistic scenario that produced a given spectrum in the future. We wanted to develop and demonstrate machine learning algorithms that will qualitatively enhance the automated identification capabilities of portable radiological sensors that are currently being used in the field.

  2. Analysis of the Correlation between GDP and the Final Consumption

    Directory of Open Access Journals (Sweden)

    Constantin ANGHELACHE

    2011-09-01

    Full Text Available This paper presents the results of the researches performed by the author regarding the evolution of Gross Domestic Product. One of the main aspects of GDP analysis is the correlation with the final consumption, an important macroeconomic indicator. The evolution of the Gross Domestic Product is highly influenced by the evolution of the final consumption. To analyze the correlation, the paper proposes the use of the linear regression model, as one of the most appropriate instruments for such scientific approach. The regression model described in the article uses the GDP as resultant variable and the final consumption as factorial variable.

  3. Trastuzumab beyond progression: overall survival analysis of the GBG 26/BIG 3-05 phase III study in HER2-positive breast cancer

    DEFF Research Database (Denmark)

    von Minckwitz, Gunter; Schwedler, Kathrin; Schmidt, Marcus;

    2011-01-01

    Continuation of trastuzumab plus capecitabine (XH) showed a significantly improved overall response rate and time to progression compared with capecitabine (X) alone in women with HER2-positive breast cancer progressing during trastuzumab treatment. Here, we report the final analysis on overall...

  4. Recent Progresses in Nanobiosensing for Food Safety Analysis.

    Science.gov (United States)

    Yang, Tao; Huang, Huifen; Zhu, Fang; Lin, Qinlu; Zhang, Lin; Liu, Junwen

    2016-01-01

    With increasing adulteration, food safety analysis has become an important research field. Nanomaterials-based biosensing holds great potential in designing highly sensitive and selective detection strategies necessary for food safety analysis. This review summarizes various function types of nanomaterials, the methods of functionalization of nanomaterials, and recent (2014-present) progress in the design and development of nanobiosensing for the detection of food contaminants including pathogens, toxins, pesticides, antibiotics, metal contaminants, and other analytes, which are sub-classified according to various recognition methods of each analyte. The existing shortcomings and future perspectives of the rapidly growing field of nanobiosensing addressing food safety issues are also discussed briefly. PMID:27447636

  5. Multiuser detection and independent component analysis-Progress and perspective

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The latest progress in the multiuser detection and independent component analysis (ICA) is reviewed systematically. Then two novel classes of multiuser detection methods based on ICA algorithms and feedforward neural networks are proposed. Theoretical analysis and computer simulation show that ICA algorithms are effective to detect multiuser signals in code-division multiple-access (CDMA) system. The performances of these methods are not identical entirely in various channels, but all of them are robust, efficient, fast and suitable for real-time implementations.

  6. Recent Progresses in Nanobiosensing for Food Safety Analysis

    Science.gov (United States)

    Yang, Tao; Huang, Huifen; Zhu, Fang; Lin, Qinlu; Zhang, Lin; Liu, Junwen

    2016-01-01

    With increasing adulteration, food safety analysis has become an important research field. Nanomaterials-based biosensing holds great potential in designing highly sensitive and selective detection strategies necessary for food safety analysis. This review summarizes various function types of nanomaterials, the methods of functionalization of nanomaterials, and recent (2014–present) progress in the design and development of nanobiosensing for the detection of food contaminants including pathogens, toxins, pesticides, antibiotics, metal contaminants, and other analytes, which are sub-classified according to various recognition methods of each analyte. The existing shortcomings and future perspectives of the rapidly growing field of nanobiosensing addressing food safety issues are also discussed briefly. PMID:27447636

  7. Gene expression analysis of relapsing– remitting, primary progressive and secondary progressive multiple sclerosis

    DEFF Research Database (Denmark)

    Ratzer, R; Søndergaard, Helle Bach; Christensen, Jeppe Romme; Börnsen, Lars Svend; Borup, Rasmus; Sørensen, Per Soelberg; Sellebjerg, Finn Thorup

    2013-01-01

    Previous studies of multiple sclerosis (MS) have indicated differences in the pathogenesis in relapsing-remitting (RRMS), secondary progressive (SPMS) and primary progressive (PPMS) disease.......Previous studies of multiple sclerosis (MS) have indicated differences in the pathogenesis in relapsing-remitting (RRMS), secondary progressive (SPMS) and primary progressive (PPMS) disease....

  8. Orthokeratology to control myopia progression: a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Yuan Sun

    Full Text Available To evaluate the clinical treatment effects of orthokeratology to slow the progression of myopia.Several well-designed controlled studies have investigated the effects of orthokeratology in school-aged children. We conducted this meta-analysis to better evaluate the existing evidence. Relevant studies were identified in the Medline and Embase database without language limitations. The main outcomes included axial length and vitreous chamber depth reported as the mean ± standard deviation. The results were pooled and assessed with a fixed-effects model analysis. Subgroup analyses were performed according to geographical location and study design.Of the seven eligible studies, all reported axial length changes after 2 years, while two studies reported vitreous chamber depth changes. The pooled estimates indicated that change in axial length in the ortho-k group was 0.27 mm (95% confidence interval [CI]: 0.22, 0.32 less than the control group. Myopic progression was reduced by approximately 45%. The combined results revealed that the difference in vitreous chamber depth between the two groups was 0.22 mm (95% confidence interval [CI]: 0.14, 0.31. None of the studies reported severe adverse events.The overall findings suggest that ortho-k can slow myopia progression in school-aged children.

  9. Severe accident analysis using dynamic accident progression event trees

    Science.gov (United States)

    Hakobyan, Aram P.

    In present, the development and analysis of Accident Progression Event Trees (APETs) are performed in a manner that is computationally time consuming, difficult to reproduce and also can be phenomenologically inconsistent. One of the principal deficiencies lies in the static nature of conventional APETs. In the conventional event tree techniques, the sequence of events is pre-determined in a fixed order based on the expert judgments. The main objective of this PhD dissertation was to develop a software tool (ADAPT) for automated APET generation using the concept of dynamic event trees. As implied by the name, in dynamic event trees the order and timing of events are determined by the progression of the accident. The tool determines the branching times from a severe accident analysis code based on user specified criteria for branching. It assigns user specified probabilities to every branch, tracks the total branch probability, and truncates branches based on the given pruning/truncation rules to avoid an unmanageable number of scenarios. The function of a dynamic APET developed includes prediction of the conditions, timing, and location of containment failure or bypass leading to the release of radioactive material, and calculation of probabilities of those failures. Thus, scenarios that can potentially lead to early containment failure or bypass, such as through accident induced failure of steam generator tubes, are of particular interest. Also, the work is focused on treatment of uncertainties in severe accident phenomena such as creep rupture of major RCS components, hydrogen burn, containment failure, timing of power recovery, etc. Although the ADAPT methodology (Analysis of Dynamic Accident Progression Trees) could be applied to any severe accident analysis code, in this dissertation the approach is demonstrated by applying it to the MELCOR code [1]. A case study is presented involving station blackout with the loss of auxiliary feedwater system for a

  10. Progressive Failure Analysis on the Single Lap Bonded Joints

    Directory of Open Access Journals (Sweden)

    Kadir TURAN

    2010-03-01

    Full Text Available In this study, the failure analysis on the single lap bonded joint, which is used for joined two composite plates each other with adhesive, is investigated experimentally and numerically. In the joint, the epoxy resin is used for adhesive and the four layered carbon fiber reinforced epoxy matrix resin composite plates are used for adherent. Numerical study is performed in the ANSYS software which is used finite element method for solution. For obtained numerical failure loads, the progressive failure analysis is used with material property degradation rules. In the failure analysis the Hashin Failure Criterion is used for composite plates and the Maximum Principal Stress failure criterion is used for adhesive. The effects of the adhesive thickness overlap lengths and plate weight on the joint strength is investigated with numerically. As a result it is seen that the failure loads is affected the bond face area. The results are presented with graphs and tables.

  11. Recent progress in protein structure analysis by NMR spectroscopy

    International Nuclear Information System (INIS)

    In recent years, many NMR methodologies have been developed to improve the molecular weight limit of protein structure analysis. Sophisticated selective stable-isotope labeling techniques such as the SAIL method solved the issue of signal reduction due to increased correlation time and that of spectral overlapping. Residual dipolar coupling and paramagnetic relaxation enhancement enabled to obtain long-range distance restraints for structure determination. NMR analysis of intrinsically disordered protein revealed novel molecular recognition mode of protein called coupling folding and binding. NMR method also revealed intermediates in macromolecular binding processes. New data acquisition techniques such the projection spectroscopy and the non-linear sampling, which introduced signal processing techniques, were developed to reduce the data acquisition time and/or increase sensitivity. In this chapter, recent progress in protein structure analysis by NMR spectroscopy is summarized. (author)

  12. Technical basis for the ITER final design report, cost review and safety analysis (FDR)

    International Nuclear Information System (INIS)

    The ITER final design report, cost review and safety analysis (FDR) is the 4th major milestone, representing the progress made in the ITER Engineering Design Activities. With the approval of the Detailed Design Report (DDR), the design work was concentrated on the requirements of operation, with only relatively minor changes to design concepts of major components. The FDR is the culmination of almost 6 years collaborative design and supporting technical work by the ITER Joint Central Team and Home Teams under the terms of the ITER EDA Agreement

  13. Methodological progresses in Markovian availability analysis and applications

    International Nuclear Information System (INIS)

    The Markovian model applied to reliability analysis is well known as an effective tool, whenever some dependencies affect the probabilistic behaviour of system's components. Its ability to study the dynamical evolution of systems allows to include human actions into the temporal evolution (inspections, maintenances, including human failure probabilities). The starting point has been the Sstagen-Mmarela code. In spite of the fact that this code already realizes much progresses towards reducing the size of markovian matrices (merging of Markov processes of systems exhibiting symmetries), there is still an imperative need to reduce memory requirements. This implies, as a first step of any realistic analysis, a modularization of the studied system into subsystems, which could be 'coupled'. The methodology is applied to the auxiliary feedwater injection of Doel 3. (orig./HSCH)

  14. Processes of energy deposition by heavy-particle and electron impact. Final progress report

    International Nuclear Information System (INIS)

    Progress is reported in three areas of reasearch during the present period: K-shell ionization in high energy collisions of heavy ions with light target atoms using the sudden (Magnus) approximation, K-L level matching phenomena associated with K-shell vacancy production in heavy-ion collisions, and studies of low energy collisions of electrons with molecules using semi-classical perturbation theory. A brief discussion of each of these activities is given

  15. Biomedical Computing Technology Information Center (BCTIC): Final progress report, March 1, 1986-September 30, 1986

    International Nuclear Information System (INIS)

    During this time, BCTIC packaged and disseminated computing technology and honored all requests made before September 1, 1986. The final month of operation was devoted to completing code requests, returning submitted codes, and sending out notices of BCTIC's termination of services on September 30th. Final BCTIC library listings were distributed to members of the active mailing list. Also included in the library listing are names and addresses of program authors and contributors in order that users may have continued support of their programs. The BCTIC library list is attached

  16. Assessment of progressive deformation on the basis of elastic analysis

    International Nuclear Information System (INIS)

    The behaviour of structures subjected to cyclic loading is complex. The structure may be in inelastic or plastic shakedown state or exhibit the ratchetting phenomenon. For reasons related to operation (functional play), geometric instability (buckling) and damage, it is important to estimate the maximum deformation reached on the structure when 'it stabilizes. A proposed solution to this problem is offered by the rule of the efficiency diagram based on a set of experimental results but, in certain cases, this method is impossible or difficult to apply. In this paper, we propose a general theoretical approach to the efficiency diagram and this will allow us to extend its field of application to cases of structures subjected to null primary loading. For this purpose, we demonstrate that, in certain cases, there is a coupling between primary and secondary loading. A new definition of primary stress, identified with the former definition in simple cases, is proposed. Finally, we will apply this method to structures bitubes and shells at free level, under thermomechanical loading and, therefore, generating secondary stresses liable to work in progressive deformation mode

  17. Fusion reactor systems studies. Progress report for the period November 1, 1996--October 31, 1997, and final report

    International Nuclear Information System (INIS)

    During FY97, the University of Wisconsin Fusion Technology Institute personnel have participated in the ARIES-RS and the ARIES-ST projects. The main areas of effort are: (1) neutronics analysis; (2) shielding of components and personnel; (3) neutron wall loading distribution; (4) radiation damage to in-vessel components; (5) components lifetimes; (6) embrittled materials designs issues; (7) stress and structural analysis; (8) activation, LOCA, and safety analysis; (9) support and fabrication of components; (10) vacuum system; and (11) maintenance. Progress made in these areas are summarized

  18. Fusion reactor systems studies. Progress report for the period November 1, 1996--October 31, 1997, and final report

    Energy Technology Data Exchange (ETDEWEB)

    El-Guebaly, L.A.; Blanchard, J.P.; Kulcinski, G.L.

    1997-08-01

    During FY97, the University of Wisconsin Fusion Technology Institute personnel have participated in the ARIES-RS and the ARIES-ST projects. The main areas of effort are: (1) neutronics analysis; (2) shielding of components and personnel; (3) neutron wall loading distribution; (4) radiation damage to in-vessel components; (5) components lifetimes; (6) embrittled materials designs issues; (7) stress and structural analysis; (8) activation, LOCA, and safety analysis; (9) support and fabrication of components; (10) vacuum system; and (11) maintenance. Progress made in these areas are summarized.

  19. Mission analysis of photovoltaic solar energy systems. Quarterly progress report, 1 June 1976-30 September 1976

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, S.L.; Rattin, E.J.; Siegel, B.

    1976-10-01

    In accordance with the revised work plan, the bulk of the effort during the quarter was devoted to Task 2, Analysis of Major Mid-Term Missions. Progress was also made, however, on Task 3, Review and Updating of the ERDA Technology Implementation Plan, and on Task 4, Critical External Issues, and a start was made on Task 5, the Impact of Incentives. Since the new plan called for phasing out of Task 1, Analysis of Near-Term Missions, and Task 6, Societal Costs of Conventional and Photovoltaic Power Production, relatively little progress was made on these tasks; the small amount of effort that was expended on them was applied to completing the final details of the studies and to beginning the preparation of final reports.

  20. Adhesive Characterization and Progressive Damage Analysis of Bonded Composite Joints

    Science.gov (United States)

    Girolamo, Donato; Davila, Carlos G.; Leone, Frank A.; Lin, Shih-Yung

    2014-01-01

    The results of an experimental/numerical campaign aimed to develop progressive damage analysis (PDA) tools for predicting the strength of a composite bonded joint under tensile loads are presented. The PDA is based on continuum damage mechanics (CDM) to account for intralaminar damage, and cohesive laws to account for interlaminar and adhesive damage. The adhesive response is characterized using standard fracture specimens and digital image correlation (DIC). The displacement fields measured by DIC are used to calculate the J-integrals, from which the associated cohesive laws of the structural adhesive can be derived. A finite element model of a sandwich conventional splice joint (CSJ) under tensile loads was developed. The simulations indicate that the model is capable of predicting the interactions of damage modes that lead to the failure of the joint.

  1. Experimental Program Final Technical Progress Report: 15 February 2007 to 30 September 2012

    Energy Technology Data Exchange (ETDEWEB)

    Kinney, Edward R. [University of Colorado, Boulder, CO

    2014-09-12

    This is the final technical report of the grant DE-FG02-04ER41301 to the University of Colorado at Boulder entitled "Intermediate Energy Nuclear Physics" and describes the results of our funded activities during the period 15 February 2007 to 30 September 2012. These activities were primarily carried out at Fermilab, RHIC, and the German lab DESY. Significant advances in these experiments were carried out by members of the Colorado group and are described in detail.

  2. Final analysis of the ALS lattice magnet data

    International Nuclear Information System (INIS)

    A preliminary analysis of the measured magnet data of the multipole magnets to be installed in the Advanced Light Source (ALS) storage ring had been given in the last conference of this series. That analysis was based on measurements of about one-third of the entire magnet complement, and some of its findings had to be revised after obtaining more data. The present paper gives an account of the integrated fundamental field strengths of all installed storage ring lattice magnets. For the multipole magnets, these values are listed as analytical expressions with four or five parameters, that cover the entire excitation range and include residual strength. Based on this final analysis, all gradient and quadrupole magnets were qualified for installation, whereas the sextupole magnets had to be individually trimmed to bring their effective fundamental strengths into the desired tolerance band

  3. [Tampa Electric Company IGCC project]. Final public design report; Technical progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    This final Public Design Report (PDR) provides completed design information about Tampa Electric Company`s Polk Power Station Unit No. 1, which will demonstrate in a commercial 250 MW unit the operating parameters and benefits of the integration of oxygen-blown, entrained-flow coal gasification with advanced combined cycle technology. Pending development of technically and commercially viable sorbent for the Hot Gas Cleanup System, the HGCU also is demonstrated. The report is organized under the following sections: design basis description; plant descriptions; plant systems; project costs and schedule; heat and material balances; general arrangement drawings; equipment list; and miscellaneous drawings.

  4. Progress Report for DOE FG02-08ER64510 (Final, April 2014)

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, Robert

    2014-04-01

    Over the course of five years we have established a long-term array of warming chambers at Duke and Harvard Forest that simulate future conditions with regard to temperature. In these chambers, we have studied, ants, other animal taxa, fungi, bacteria and plants and their responses to the treatments. We have coupled these studies with lab experiments, large-scale observations, and models to contextualize our results. Finally, we have developed integrative models of the future distribution of species and their consequences as a result of warming in eastern North America and more generally.

  5. Fuel Storage Facility Final Safety Analysis Report. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Linderoth, C.E.

    1984-03-01

    The Fuel Storage Facility (FSF) is an integral part of the Fast Flux Test Facility. Its purpose is to provide long-term storage (20-year design life) for spent fuel core elements used to provide the fast flux environment in FFTF, and for test fuel pins, components and subassemblies that have been irradiated in the fast flux environment. This Final Safety Analysis Report (FSAR) and its supporting documentation provides a complete description and safety evaluation of the site, the plant design, operations, and potential accidents.

  6. A Portfolio Analysis Tool for Measuring NASAs Aeronautics Research Progress toward Planned Strategic Outcomes

    Science.gov (United States)

    Tahmasebi, Farhad; Pearce, Robert

    2016-01-01

    Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. The strategic planning process for determining the community Outcomes is also briefly described. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples are also presented.

  7. Diffusion tensor analysis of corpus callosum in progressive supranuclear palsy

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Shoichi; Makino, Takahiro; Shirai, Wakako; Hattori, Takamichi [Department of Neurology, Graduate School of Medicine, Chiba University (Japan)

    2008-11-15

    Progressive supranuclear palsy (PSP) is a neurodegenerative disease featuring parkinsonism, supranuclear ophthalmoplegia, dysphagia, and frontal lobe dysfunction. The corpus callosum which consists of many commissure fibers probably reflects cerebral cortical function. Several previous reports showed atrophy or diffusion abnormalities of anterior corpus callosum in PSP patients, but partitioning method used in these studies was based on data obtained in nonhuman primates. In this study, we performed a diffusion tensor analysis using a new partitioning method for the human corpus callosum. Seven consecutive patients with PSP were compared with 29 age-matched patients with Parkinson's Disease (PD) and 19 age-matched healthy control subjects. All subjects underwent diffusion tensor magnetic resonance imaging, and the corpus callosum was partitioned into five areas on the mid-sagittal plane according to a recently established topography of human corpus callosum (CC1-prefrontal area, CC2-premotor and supplementary motor area, CC3-motor area, CC4-sensory area, CC5-parietal, temporal, and occipital area). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured in each area and differences between groups were analyzed. In the PSP group, FA values were significantly decreased in CC1 and CC2, and ADC values were significantly increased in CC1 and CC2. Receiver operating characteristic analysis showed excellent reliability of FA and ADC analyses of CC1 for differentiating PSP from PD. The anterior corpus callosum corresponding to the prefrontal, premotor, and supplementary motor cortices is affected in PSP patients. This analysis can be an additional test for further confirmation of the diagnosis of PSP.

  8. Diffusion tensor analysis of corpus callosum in progressive supranuclear palsy

    International Nuclear Information System (INIS)

    Progressive supranuclear palsy (PSP) is a neurodegenerative disease featuring parkinsonism, supranuclear ophthalmoplegia, dysphagia, and frontal lobe dysfunction. The corpus callosum which consists of many commissure fibers probably reflects cerebral cortical function. Several previous reports showed atrophy or diffusion abnormalities of anterior corpus callosum in PSP patients, but partitioning method used in these studies was based on data obtained in nonhuman primates. In this study, we performed a diffusion tensor analysis using a new partitioning method for the human corpus callosum. Seven consecutive patients with PSP were compared with 29 age-matched patients with Parkinson's Disease (PD) and 19 age-matched healthy control subjects. All subjects underwent diffusion tensor magnetic resonance imaging, and the corpus callosum was partitioned into five areas on the mid-sagittal plane according to a recently established topography of human corpus callosum (CC1-prefrontal area, CC2-premotor and supplementary motor area, CC3-motor area, CC4-sensory area, CC5-parietal, temporal, and occipital area). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured in each area and differences between groups were analyzed. In the PSP group, FA values were significantly decreased in CC1 and CC2, and ADC values were significantly increased in CC1 and CC2. Receiver operating characteristic analysis showed excellent reliability of FA and ADC analyses of CC1 for differentiating PSP from PD. The anterior corpus callosum corresponding to the prefrontal, premotor, and supplementary motor cortices is affected in PSP patients. This analysis can be an additional test for further confirmation of the diagnosis of PSP

  9. Final Safety Analysis Report (FSAR) for Building 332, Increment III

    Energy Technology Data Exchange (ETDEWEB)

    Odell, B. N.; Toy, Jr., A. J.

    1977-08-31

    This Final Safety Analysis Report (FSAR) supplements the Preliminary Safety Analysis Report (PSAR), dated January 18, 1974, for Building 332, Increment III of the Plutonium Materials Engineering Facility located at the Lawrence Livermore Laboratory (LLL). The FSAR, in conjunction with the PSAR, shows that the completed increment provides facilities for safely conducting the operations as described. These documents satisfy the requirements of ERDA Manual Appendix 6101, Annex C, dated April 8, 1971. The format and content of this FSAR complies with the basic requirements of the letter of request from ERDA San to LLL, dated March 10, 1972. Included as appendices in support of th FSAR are the Building 332 Operational Safety Procedure and the LLL Disaster Control Plan.

  10. Advanced Coal Conversion Process Demonstration Project. Final technical progress report, January 1, 1995--December 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    This report describes the technical progress made on the Advanced Coal Conversion Process (ACCP) Demonstration Project from January 1, 1995 through December 31, 1995. This project demonstrates an advanced, thermal, coal upgrading process, coupled with physical cleaning techniques, that is designed to upgrade high-moisture, low-rank coals to a high-quality, low-sulfur fuel, registered as the SynCoal Process. The coal is processed through three stages (two heating stages followed by an inert cooling stage) of vibrating fluidized bed reactors that remove chemically bound water, carboxyl groups, and volatile sulfur compounds. After thermal upgrading, the coal is put through a deep-bed stratifier cleaning process to separate the pyrite-rich ash from the coal. The SynCoal Process enhances low-rank, western coals, usually with a moisture content of 25 to 55 percent, sulfur content of 0.5 to 1.5 percent, and heating value of 5,5000 to 9,000 British thermal units per pound (Btu/lb), by producing a stable, upgraded, coal product with a moisture content as low as 1 percent, sulfur content as low as 0.3 percent, and heating value up to 12,000 Btu/lb. During this reporting period, the primary focus for the ACCP Demonstration Project team was to expand SynCoal market awareness and acceptability for both the products and the technology. The ACCP Project team continued to focus on improving the operation, developing commercial markets, and improving the SynCoal products as well as the product`s acceptance.

  11. Light scattering studies of lower dimensional colloidal particle and critical fluid systems. Final progress report

    International Nuclear Information System (INIS)

    We have completed a program of small angle scattering Rayleigh linewidth measurements on thin films of a 2,6-lutidine + water mixture. No statistically significant departures from three dimensional dynamic response were seen, although the conditions set by the theory of Calvo and Ferrell were met. We have applied digital image processing to evaluate fractal scale invariance in two dimensional particle aggregates arising from the induced coagulation of colloidal particle monolayer crystals. Our system gives us the capability of calculating the pair correlation function for both small and very large (2 x 104 particles) particle clusters. We find evidence of an apparent crossover between kinetic clustering aggregation at small distances (about 20 particle diameters) to percolation or gel/sol transition-behavior at large distances. This is evident in both isolated clusters and in final state ''giant'' aggregates. We are carrying through a parallel program of computer calculations whose motivation is to assess the sensitivity of experimental measures of self similarity to cluster size and image resolution, and to generate efficient algorithms which can be applied to calculate fractal ''critical exponents'' other than the Hausdorff dimension. We have succeeded in measuring the surface tension of a water surface covered by a colloidal particle monolayer crystal, in both its repulsive-dipole and close-packed van der Waals phases

  12. Theoretical studies in nuclear structure. Final progress report, June 1, 1991--July 31, 1996

    International Nuclear Information System (INIS)

    The general purview of the project is the theory of collective motion in atomic nuclei. The chief aim is to elucidate the phenomena of (1) anharmonic multiphonon excitations, and (2) collective tilted rotation, both of which are topics of considerable current interest. In the primary stage of an investigation it is often necessary to develop appropriate mathematical tools, as was the case here. In the next stage, the formalism must be tested on simple soluble models. The work described here is mainly concerned with these two stages. The final stage of realistic applications will require more time, manpower and, of course, the necessary funding. Some planning for this last stage has been carried out and anticipated problems axe briefly discussed. As it turns out, both of the above topics can be approached within the unified framework of a theorem that I developed, called the Cranking Bifurcation Theorem (CBT) to be described below. The CBT can be regarded as an outgrowth of the boson expansion method, which provides a general, and, in principal, exact formalism for treating collective excitations. We begin with a brief discussion of the CBT and then continue on to the applications

  13. Final Progress Report for Award DE-FG07-05ID14637.pdf

    Energy Technology Data Exchange (ETDEWEB)

    Cathy Dixon

    2012-03-09

    2004-2011 Final Report for AFCI University Fellowship Program. The goal of this effort was to be supportive of university students and university programs - particularly those students and programs that will help to strengthen the development of nuclear-related fields. The program also supported the stability of the nuclear infrastructure and developed research partnerships that are helping to enlarge the national nuclear science technology base. In this fellowship program, the U.S. Department of Energy sought master's degree students in nuclear, mechanical, or chemical engineering, engineering/applied physics, physics, chemistry, radiochemistry, or fields of science and engineering applicable to the AFCI/Gen IV/GNEP missions in order to meet future U.S. nuclear program needs. The fellowship program identified candidates and selected full time students of high-caliber who were taking nuclear courses as part of their degree programs. The DOE Academic Program Managers encouraged fellows to pursue summer internships at national laboratories and supported the students with appropriate information so that both the fellows and the nation's nuclear energy objectives were successful.

  14. [Geothermal system temperature-depth database and model for data analysis]. 5. quarterly technical progress report

    Energy Technology Data Exchange (ETDEWEB)

    Blackwell, D.D.

    1998-04-25

    During this first quarter of the second year of the contract activity has involved several different tasks. The author has continued to work on three tasks most intensively during this quarter: the task of implementing the data base for geothermal system temperature-depth, the maintenance of the WWW site with the heat flow and gradient data base, and finally the development of a modeling capability for analysis of the geothermal system exploration data. The author has completed the task of developing a data base template for geothermal system temperature-depth data that can be used in conjunction with the regional data base that he had already developed and is now implementing it. Progress is described.

  15. Learning Progressions and Teaching Sequences: A Review and Analysis

    Science.gov (United States)

    Duschl, Richard; Maeng, Seungho; Sezen, Asli

    2011-01-01

    Our paper is an analytical review of the design, development and reporting of learning progressions and teaching sequences. Research questions are: (1) what criteria are being used to propose a "hypothetical learning progression/trajectory" and (2) what measurements/evidence are being used to empirically define and refine a "hypothetical learning…

  16. Coal plasticity at high heating rates and temperatures. Final technical progress report

    Energy Technology Data Exchange (ETDEWEB)

    Gerjarusak, S.; Peters, W.A.; Howard, J.B.

    1995-05-01

    Plastic coals are important feedstocks in coke manufacture, coal liquefaction, gasification, and combustion. During these processes, the thermoplastic behavior of these coals is also important since it may contribute to desirable or undesirable characteristics. For example, during liquefaction, the plastic behavior is desired since it leads to liquid-liquid reactions which are faster than solid-liquid reactions. During gasification, the elastic behavior is undesired since it leads to caking and agglomeration of coal particles which result in bed bogging in fixed or fluidized bed gasifiers. The plastic behavior of different coals was studied using a fast-response plastometer. A modified plastometer was used to measure the torque required to turn at constant angular speed a cone-shaped disk embedded in a thin layer of coal. The coal particles were packed between two metal plates which are heated electrically. Heating rates, final temperatures, pressures, and durations of experiment ranged from 200--800 K/s, 700--1300 K, vacuum-50 atm helium, and 0--40 s, respectively. The apparent viscosity of the molten coal was calculated from the measured torque using the governing equation of the cone-and-plate viscometer. Using a concentrated suspension model, the molten coal`s apparent viscosity was related to the quantity of the liquid metaplast present during pyrolysis. Seven coals from Argonne National Laboratory Premium Coal Sample Bank were studied. Five bituminous coals, from high-volatile to low-volatile bituminous, were found to have very good plastic behavior. Coal type strongly affects the magnitude and duration of plasticity. Hvb coals were most plastic. Mvb and lvb coals, though the maximum plasticity and plastic period were less. Low rank coals such as subbituminous and lignite did not exhibit any plasticity in the present studies. Coal plasticity is moderately well correlated with simple indices of coal type such as the elemental C,O, and H contents.

  17. Diagnostic development and support of MHD test facilities. Final progress report, March 1980--March 1994

    Energy Technology Data Exchange (ETDEWEB)

    1995-02-01

    The Diagnostic Instrumentation and Analysis Laboratory (DIAL) at Mississippi State University (MSU), under U.S. Department of Energy (DOE) Contract No. DE-AC02-80ET-15601, Diagnostic Development and Support of MHD Test Facilities, developed diagnostic instruments for magnetohydrodynamic (MHD) power train data acquisition and for support of MHD component development test facilities. Microprocessor-controlled optical instruments, initially developed for Heat Recovery/Seed Recovery (HRSR) support, were refined, and new systems to measure temperatures and gas-seed-slag stream characteristics were developed. To further data acquisition and analysis capabilities, the diagnostic systems were interfaced with DIAL`s computers. Technical support was provided for the diagnostic needs of the national MHD research effort. DIAL personnel also cooperated with government agencies and private industries to improve the transformation of research and development results into processes, products and services applicable to their needs. The initial contract, Testing and Evaluation of Heat Recovery/Seed Recovery, established a data base on heat transfer, slagging effects on heat transfer surfaces, metal durability, secondary combustor performance, secondary combustor design requirements, and other information pertinent to the design of HR/SR components at the Coal-Fired Flow Facility (CFFF). To accomplish these objectives, a combustion test stand was constructed that simulated MHD environments, and mathematical models were developed and evaluated for the heat transfer in hot-wall test sections. Two transitions occurred during the span of this contract. In May 1983, the objectives and title of the contract changed from Testing and Evaluation of Heat Recovery/Seed Recovery to Diagnostic Development and Support of MHD Test Facilities. In July 1988, the research laboratory`s name changed from the MHD Energy Center to the Diagnostic Instrumentation and Analysis Laboratory.

  18. Final Progress Report for Linking Ion Solvation and Lithium Battery Electrolyte Properties

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, Wesley

    2014-08-29

    The research objective of this proposal was to provide a detailed analysis of how solvent and anion structure govern the solvation state of Li+ cations in solvent-LiX mixtures and how this, in turn, dictates the electrolyte physicochemical and electrochemical properties which govern (in part) battery performance. Lithium battery electrolytes remain a poorly understood and hardly studied topic relative to the research devoted to battery electrodes. This is due to the fact that it is the electrodes which determine the energy (capacity) of the battery. The electrolyte, however, plays a crucial role in the practical energy density, power, low and/or high temperature performance, lifetime, safety, etc. which is achievable. The development within this project of a "looking glass" into the molecular interactions (i.e., solution structure) in bulk electrolytes through a synergistic experimental approach involving three research thrusts complements work by other researchers to optimize multi-solvent electrolytes and efforts to understand/control the electrode-electrolyte interfaces, thereby enabling the rational design of electrolytes for a wide variety of battery chemistries and applications (electrolytes-on-demand). The three research thrusts pursued include: (1) conduction of an in-depth analysis of the thermal phase behavior of diverse solvent-LiX mixtures, (2) exploration of the ionic association/solvate formation behavior of select LiX salts with a wide variety of solvents, and (3) linking structure to properties-determination of electrolyte physicochemical and electrochemical properties for comparison with the ionic association and phase behavior.

  19. Analysis of progression of severe accident in Indian PHWRs

    International Nuclear Information System (INIS)

    In India a wide variety of nuclear reactors are in operation and in different stages of construction. The main stay of Indian nuclear power programme today is 'Pressurised Heavy Water Reactors (PHWRs)'. There are 13 operating PHWRs and several others in different stages of construction. These reactors are either of 220 MWe or 540 MWe capacity. Atomic Energy Regulatory Board for authorization needs safety analysis reports, which consists of a detailed analyses of all design basis accidents. However, there is a more to carry out severe accident analysis for accident management programme. This paper describes an analysis of a severe accident caused by Loss of Coolant Accident (LOCA), co-incident with loss of emergency core cooling system and loss of moderator heat sink in 220 MWe Indian PHWR. Initially in a matter of about 60 seconds most of the coolant from primary heat transport system blows out, the reactor gets tripped, but in the absence of emergency core cooling system, the heat removal from the fuel bundles is very poor. Consequently, the fuel bundle starts getting heated up. The only mode of heat transfer is radiative heat transfer from fuel bundle to pressure tube, from pressure tube to calandria tube and them convective heat transfer from calandria tube to the relatively cold moderator in which the reactor channels are immersed. In the absence of availability of moderator heat sink the moderator gets heated up and eventually boils. And slowly the moderator level in the calandria starts falling. Soon the channel gets uncovered and the temperatures of the channel components shoot up as the temperature of the pressure tube and calandria tube rise. Mechanical properties deteriorate rapidly with temperature as structural elements of reactor channel are made of zircaloy. Under the weight of the fuel, the reactor channel gives in and falls into the remaining moderator. This process continues till all the moderator is evaporated, leading to damage to the entire

  20. Final Technical Progress Report Long term risk from actinides in the environment: Modes of mobility

    International Nuclear Information System (INIS)

    in diameter and approximately 22 cm long. A thin ''marker layer'' of white soil was added to the top of each column followed by a thin layer of soil that had been spiked with 137Cs, cerium and lanthanum was applied to the surface. Approximately 900 cm of water (the equivalent of about 30 years of rainfall) was then applied at a rate of 3.2 L d-1. All of the activity contained in the soil core appeared to be in the top few mm of soil, i.e. there was virtually no movement of the 134Cs labeled particles. Finally, a library of object-oriented model components was created using Visual Basic to support the construction of contaminant transport models. These components greatly simplify the task of building 1- to 3- dimensional simulation models for risk assessment. The model components created under this funding were subsequently applied to help answer questions regarding risks from irrigation associated with potential releases from the Yucca Mountain waste repository

  1. Final Technical Progress Report Long term risk from actinides in the environment: Modes of mobility

    Energy Technology Data Exchange (ETDEWEB)

    Thomas B. Kirchner

    2002-03-22

    in diameter and approximately 22 cm long. A thin ''marker layer'' of white soil was added to the top of each column followed by a thin layer of soil that had been spiked with 137Cs, cerium and lanthanum was applied to the surface. Approximately 900 cm of water (the equivalent of about 30 years of rainfall) was then applied at a rate of 3.2 L d-1. All of the activity contained in the soil core appeared to be in the top few mm of soil, i.e. there was virtually no movement of the 134Cs labeled particles. Finally, a library of object-oriented model components was created using Visual Basic to support the construction of contaminant transport models. These components greatly simplify the task of building 1- to 3- dimensional simulation models for risk assessment. The model components created under this funding were subsequently applied to help answer questions regarding risks from irrigation associated with potential releases from the Yucca Mountain waste repository.

  2. Urban Integrated Industrial Cogeneration Systems Analysis. Phase II final report

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    Through the Urban Integrated Industrial Cogeneration Systems Analysis (UIICSA), the City of Chicago embarked upon an ambitious effort to identify the measure the overall industrial cogeneration market in the city and to evaluate in detail the most promising market opportunities. This report discusses the background of the work completed during Phase II of the UIICSA and presents the results of economic feasibility studies conducted for three potential cogeneration sites in Chicago. Phase II focused on the feasibility of cogeneration at the three most promising sites: the Stockyards and Calumet industrial areas, and the Ford City commercial/industrial complex. Each feasibility case study considered the energy load requirements of the existing facilities at the site and the potential for attracting and serving new growth in the area. Alternative fuels and technologies, and ownership and financing options were also incorporated into the case studies. Finally, site specific considerations such as development incentives, zoning and building code restrictions and environmental requirements were investigated.

  3. Using of BEPU methodology in a final safety analysis report

    International Nuclear Information System (INIS)

    The Nuclear Reactor Safety (NRS) has been established since the discovery of nuclear fission, and the occurrence of accidents in Nuclear Power Plants worldwide has contributed for its improvement. The Final Safety Analysis Report (FSAR) must contain complete information concerning safety of the plant and plant site, and must be seen as a compendium of NRS. The FSAR integrates both the licensing requirements and the analytical techniques. The analytical techniques can be applied by using a realistic approach, addressing the uncertainties of the results. This work aims to show an overview of the main analytical techniques that can be applied with a Best Estimated Plus Uncertainty (BEPU) methodology, which is 'the best one can do', as well as the ALARA (As Low As Reasonably Achievable) principle. Moreover, the paper intends to demonstrate the background of the licensing process through the main licensing requirements. (author)

  4. [Experimental research in high energy physics: Final technical progress report, 1986--1992

    International Nuclear Information System (INIS)

    This is the closeout report for DOE supported research in high energy physics for the period 1986--1992, under contract award AT03-86ER40249 at the Santa Cruz Institute for Particle Physics (SCIPP) at U.C. Santa Cruz. The research during this period consisted primarily of the following: Data taking with the MARK II detector at the SLC at SLAC and construction of a silicon vertex detector for the MARK II. This effort included substantial work on commissioning of the SLC accelerator. Preparation of the SLD experiment for the SLC, and initial data taking with this experiment. Participation in the ALEPH physics program at LEP at CERN in Geneva, with an emphasis on its silicon vertex detector. Analysis of data collected with the MARK III experiment at the SPEAR accelerator at SLAC. Electronics development for the leading proton spectrometer for the ZEUS experiment at DESY in Hamburg. Design, testing and physics studies for a silicon tracker for the SSC. Theoretical physics program emphasizing phenomenology, Higgs physics, supersymmetry, and some issues in cosmology

  5. Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS

    Directory of Open Access Journals (Sweden)

    O'Connell Thomas M

    2010-03-01

    Full Text Available Abstract Background Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentrations or profiles in response to perturbation through disease, toxicants or drugs. The spectra generated through such analyses are typically confounded by noise of various types, obscuring the signals and hindering downstream statistical analysis. Such issues are becoming increasingly significant as greater numbers of large-scale systems or longitudinal studies are being performed, in which many spectra from different conditions need to be compared simultaneously. Results We describe a novel approach, termed Progressive Consensus Alignment of Nmr Spectra (PCANS, for the alignment of NMR spectra. Through the progressive integration of many pairwise comparisons, this approach generates a single consensus spectrum as an output that is then used to adjust the chemical shift positions of the peaks from the original input spectra to their final aligned positions. We characterize the performance of PCANS by aligning simulated NMR spectra, which have been provided with user-defined amounts of chemical shift variation as well as inter-group differences as would be observed in control-treatment applications. Moreover, we demonstrate how our method provides better performance than either template-based alignment or binning. Finally, we further evaluate this approach in the alignment of real mouse urine spectra and demonstrate its ability to improve downstream PCA and PLS analyses. Conclusions By avoiding the use of a template or reference spectrum, PCANS allows for the creation of a consensus spectrum that enhances the signals within the spectra while maintaining sample-specific features. This approach is of greatest benefit when complex samples are being analyzed and where it is expected that there will be spectral features unique and/or strongly different between subgroups

  6. System variability analysis for final disposal concept of radwaste

    International Nuclear Information System (INIS)

    This paper is the first of a series designed to contribute to the verification and quality assurance of deterministic and probabilistic system assessments codes which are of particular interest for use in the assessment of the disposal of radioactive wastes. A system model is used that describes a hypothetical disposal concept in granite formation. The estimation of dose rates at different time moments is the principal aim of this paper. This is made by using two approaches: deterministic and probabilistic or stochastic. We have taken into account seven representative fission products with a total of 22 parameters that are represented by the best estimate values or probability distributions, including 14 radionuclide specific parameters. A computer code PSAC for an CDC-CYBER 830 has been elaborated for both deterministic and probabilistic models. The local sensitivity analysis for deterministic models has been approached. An uncertainty analysis has been performed for probabilistic models. Finally, it is concluded that the results produced are very consistent and could form a basis for further developments. (Author)

  7. Final Technical Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    J.Y. Hwang; R.C. Greenlund

    2002-12-31

    Michigan Technological University has demonstrated major inroads in establishing the viability of utilizing aluminum smelting by-product waste materials in lightweight concrete product applications. The research identified key elements of producing various forms of lightweight concrete products through utilizing various procedures and mixture components with the by-product materials. A process was developed through pilot plant testing that results in additional aluminum recovery at finer sizes, a clean returnable salt product through spray drying technology, and a low-salt-content oxide product with enough aluminum metal content that it can be used to form lightweight cementitious mixtures. Having three distinct products aids in generating favorable process economics. Revenue projections from aluminum recovery and salt recovery are enough to cover processing costs and create a cost-free oxide product to market for lightweight concrete applications. This supply side commercialization strategy offers aluminum by-product recyclers a potentially no cost product, which has been demonstrated through this project to create desirable and marketable lightweight concrete products of various forms. Environmental benefits to the public are tremendous. At best, all dross and salt cake materials have the potential to be completely recycled and utilized. At worst, disposal sites would see a reduced amount of material: a post processed oxide product with little salt and no hydrogen sulfide or ammonia gas generating capability, which, if isolated from high alkali conditions, would pose no reactivity concerns. The US aluminum industry has historically, along with the steel industry, been a leader in recycling metal. The findings from this project, increased metal recovery, improved salt recycling, and demonstrated end uses for oxide residues, will go a long way in helping the aluminum industry obtain 100% material utilization and zero discharge.

  8. Final Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Kotov, Valeri [Univ. of Vermont, Burlington, VT (United States)

    2016-05-29

    The research in this program involves theoretical investigations of electronic, optical and mechanical properties of graphene and its derivatives, such as bi-layer graphene, graphene-based van der Waals heterostructures, strained graphene, as well as graphene on various surfaces. One line of research has been development of theoretical models that support graphene’s large array of possible technological applications. For example one of our goals has been the understanding of surface plasmons and spin relaxation mechanisms in graphene, related to novel optoelectronics and spintronics applications. Our current research focus is on understanding the role of correlations in graphene under mechanical deformations, such as strain. The main goal is to describe the mutual interplay between strain and electron-electron interactions which could lead to the formation of novel elec- tronic phases with strongly modified electronic, magnetic and optical properties. This direction of research contributes to deeper understanding of interactions in graphene and related atomically-thin materials - a subject at the forefront of research on graphene and its derivatives.

  9. Final Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Bernstein, Herbert J

    2012-02-06

    The BIOMOL grant was for 'Local System Support for PDB Biological Unit Search and Display' to augment Rasmol's [Bernstein 2000] [Sayle, Milner-White 1995] existing macromolecular display functions with new capabilities by taking advantage of recent increases in local computing power in order to move functionality that is now scattered among various local and remote systems into one local package. Work included new algorithms for molecular surface display, an extended format for Protein Data Bank Entries, work on issues relating to the integration of multiple diffraction images formats.

  10. Progress Toward the Analysis of the Kinetic Stabilizer Concept

    Energy Technology Data Exchange (ETDEWEB)

    Post, R F; Byers, J A; Cohen, R H; Fowler, T K; Ryutov, D D; Tung, L S

    2005-02-08

    too low in density to stabilize the plasmas in the plug cells and the central cell. The K-S resolves this dilemma by employing ion beams injected up the magnetic gradient in the ''expander'' region outside the outermost mirror in such a way that as they are compressed, stagnated, and reflected they form a ''stabilizer'' plasma in the expander. Preliminary calculations [1] showed that the power required to maintain the stabilizer beams would be orders of magnitude less than the fusion power generated. This report reviews those calculations and describes additional theoretical and computational work in progress, aimed at confirming and extending the analysis of the K-S concept as applied to axisymmetric tandem mirror systems.

  11. Final report on progress of grant ''Few-nucleon systems in the laboratory, supernovae, and the cosmos''

    International Nuclear Information System (INIS)

    In the past year I have pursued work in three different areas within the scope of my Department of Energy Outstanding Junior Investigator Award ''Few-nucleon systems in the laboratory, supernovae, and the cosmos''. The first, and main, focus of my research has been testing the usefulness of effective field theory (EFT) in describing Compton scattering for different targets: the proton, deuterium, and Helium-3. This has been where the bulk of my OJI effort has been dedicated in the past twelve months, and thus it is the longest section of this report. Secondly, I have been working on the application of EFT to the reaction π-d → γnn. Finally, I have also been involved in a non-EFT project: computing certain many-body effects which affect the neutrino cooling of neutron stars and supernovae. In what follows I first describe my work in each of these areas. I then discuss unexpended funds, and the students who have been supported under the aegis of this project, as well as listing publications, talks, etc. associated with this grant in 2004-05. This report describes progress made on research projects associated with my Department of Energy Outstanding Junior Investigator grant

  12. Analysis of Member State RED implementation. Final Report (Task 2)

    Energy Technology Data Exchange (ETDEWEB)

    Peters, D.; Alberici, S.; Toop, G. [Ecofys, Utrecht (Netherlands); Kretschmer, B. [Institute for European Environmental Policy IEEP, London (United Kingdom)

    2012-12-15

    This report describes the way EU Member States have transposed the sustainability and chain of custody requirements for biofuels as laid down in the Renewable Energy Directive (RED) and Fuel Quality Directive (FQD). In the assessment of Member States' implementation, the report mainly focuses on effectiveness and administrative burden. Have Member States transposed the Directives in such a way that compliance with the sustainability criteria can be ensured as effectively as possible? To what extent does the Member States' implementation lead to unnecessary administrative burden for economic operators in the (bio)fuel supply chain? The report focuses specifically on the transposition of the sustainability and chain of custody requirements, not on the target for renewables on transport. This means that for example the double counting provision is not included as part of the scope of this report. This report starts with an introduction covering the implementation of the Renewable Energy (and Fuel Quality) Directive into national legislation, the methodology by which Member States were assessed against effectiveness and administrative burden and the categorisation of Member State's national systems for RED-implementation (Chapter 1). The report continues with a high level description of each Member State system assessed (Chapter 2). Following this, the report includes analysis of the Member States on the effectiveness and administrative burden of a number of key ('major') measures (Chapter 3). The final chapter presents the conclusions and recommendations (Chapter 4)

  13. Transportable cesium irradiator (TPCI): Final safety analysis report: Revision 1

    International Nuclear Information System (INIS)

    This Final Safety Analysis Report describes the Transportable Cesium Irradiator (TPCI) and assesses the hazards associated with its operation. The TPCI consists of a mobile, lead-shielded, irradiation unit with support equipment mounted within an enclosed trailer. The irradiation unit has two basic compartments; a source chamber sized to mate with the transportation cask which houses the source capsules, and an irradiation chamber formed as a large shielded cylinder (drum) with a window. The irradiation chamber is mounted on a large diameter support bearing. As this chamber is rotated its window moves from the product access door, where produce is inserted or extracted, to a position in line with a similar window in the source chamber. When the windows are aligned the produce is irradiated, while the back wall of the irradiation chamber shields the product access door. The TPCI is designed to be transported throughout the continental United States. The transportation cask containing the cesium source capsules is transported separately from the irradiation unit and is installed when the TPCI unit has been readied for operation at a particular site. The transportation cask is a separate unit and is documented in a separate FSAR

  14. The Analysis of the Thematic Progression Patterns in "The Great Learning"

    Institute of Scientific and Technical Information of China (English)

    王利娜; 金俊淑

    2007-01-01

    This paper intends to introduce briefly the thematic progression patterns in Systemic- Functional Grammar, then analyze its application in "The Great Learning" which is one of the classics of the Confucius and his disciples. The analysis of the thematic progression patterns of "The Great Learning" is meaningful for both understanding and appreciating "The Great Learning".

  15. Human Capital Investment and an Analysis of Its Progressive Profit

    Institute of Scientific and Technical Information of China (English)

    张德平; 孙诚

    2004-01-01

    Skilled labor force cultivated through putting in funds and time in their education are undoubtedly essential in the operation of sophisticated machines in production, but it is so also in the creation of new ideas and methods in production and other economic activities, and ultimately in the promotion of the progressive increase of material capital. Thus strengthening the investment of human capital and enriching the stock of human capital is of primary importance, especially for China, in the 21st century.

  16. 10 CFR 52.157 - Contents of applications; technical information in final safety analysis report.

    Science.gov (United States)

    2010-01-01

    ... requirements in 10 CFR Chapter I, including: (1) An analysis and evaluation of the design and performance of...; technical information in final safety analysis report. The application must contain a final safety analysis... NRC: (a) The principal design criteria for the reactor to be manufactured. Appendix A of 10 CFR...

  17. Progress and challenges in the development and qualification of multi-level multi-physics coupled methodologies for reactor analysis

    International Nuclear Information System (INIS)

    Current trends in nuclear power generation and regulation as well as the design of next generation reactor concepts along with the continuing computer technology progress stimulate the development, qualification and application of multi-physics multi-scale coupled code systems. The efforts have been focused on extending the analysis capabilities by coupling models, which simulate different phenomena or system components, as well as on refining the scale and level of detail of the coupling. This paper reviews the progress made in this area and outlines the remaining challenges. The discussion is illustrated with examples based on neutronics/thermohydraulics coupling in the reactor core modeling. In both fields recent advances and developments are towards more physics-based high-fidelity simulations, which require implementation of improved and flexible coupling methodologies. First, the progresses in coupling of different physics codes along with the advances in multi-level techniques for coupled code simulations are discussed. Second, the issues related to the consistent qualification of coupled multi-physics and multi-scale code systems for design and safety evaluation are presented. The increased importance of uncertainty and sensitivity analysis are discussed along with approaches to propagate the uncertainty quantification between the codes. The incoming OECD LWR Uncertainty Analysis in Modeling (UAM) benchmark is the first international activity to address this issue and it is described in the paper. Finally, the remaining challenges with multi-physics coupling are outlined. (authors)

  18. An Archetypal Analysis on The Pilgrim’s Progress

    Institute of Scientific and Technical Information of China (English)

    杨洛琪

    2014-01-01

    John Bunyan (1628-1688) is one of the most remarkable figures in 17th century English literature.He is famous for his authorship of The Pilgrim’s Progress and becomes one of the world’s most widely-read Christian writers.This thesis attempts to use the archetypal theories to analyze the archetypes on Christian culture in The Pilgrim’s Progress.According to the theory of archetype, Bunyan’s use of biblical images and themes can be called archetypes.Therefore, this thesis tries to explore the underlying archetypal elements so as to represent its literary treasures by resorting to the theory of archetypal criticism.%约翰·班扬是十七世纪英国文学史上最伟大的作家之一,其著作《天路历程》让他成为最受欢迎的基督教作家。本文从原型批评理论的角度阐释了《天路历程》中来自基督教的文化原型。这些原型涉及作品的圣经意象:水和主题两个方面。从原型角度研究了《天路历程》的根据及重要性。

  19. Analysis of breast cancer progression using principal component analysis and clustering

    Indian Academy of Sciences (India)

    G Alexe; G S Dalgin; S Ganesan; C DeLisi; G Bhanot

    2007-08-01

    We develop a new technique to analyse microarray data which uses a combination of principal components analysis and consensus ensemble -clustering to find robust clusters and gene markers in the data. We apply our method to a public microarray breast cancer dataset which has expression levels of genes in normal samples as well as in three pathological stages of disease; namely, atypical ductal hyperplasia or ADH, ductal carcinoma in situ or DCIS and invasive ductal carcinoma or IDC. Our method averages over clustering techniques and data perturbation to find stable, robust clusters and gene markers. We identify the clusters and their pathways with distinct subtypes of breast cancer (Luminal, Basal and Her2+). We confirm that the cancer phenotype develops early (in early hyperplasia or ADH stage) and find from our analysis that each subtype progresses from ADH to DCIS to IDC along its own specific pathway, as if each was a distinct disease.

  20. Meta-analysis in Stata: history, progress and prospects

    OpenAIRE

    Jonathan Sterne

    2004-01-01

    Systematic reviews of randomised trials are now widely recognised to be the best way to summarise the evidence on the effects of medical interventions. A systematic review may (though it need not) contain a meta-analysis, `a statistical analysis which combines the results of several independent studies considered by the analyst to be "combinable" '. The first researcher to do a meta-analysis was probably Karl Pearson, in 1904. Sadly, Stata was not available at this time. The first Stata comma...

  1. ANALYSIS OF THE TANK 6F FINAL CHARACTERIZATION SAMPLES-2012

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L.; Diprete, D.; Coleman, C.; Hay, M.; Shine, G.

    2012-06-28

    The Savannah River National Laboratory (SRNL) was requested by Savannah River Remediation (SRR) to provide sample preparation and analysis of the Tank 6F final characterization samples to determine the residual tank inventory prior to grouting. Fourteen residual Tank 6F solid samples from three areas on the floor of the tank were collected and delivered to SRNL between May and August 2011. These Tank 6F samples were homogenized and combined into three composite samples based on a proportion compositing scheme and the resulting composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 6F composite samples include bulk density and water leaching of the solids to account for water soluble components. The composite Tank 6F samples were analyzed and the data reported in triplicate. Sufficient quality assurance standards and blanks were utilized to demonstrate adequate characterization of the Tank 6F samples. The main evaluation criteria were target detection limits specified in the technical task request document. While many of the target detection limits were met for the species characterized for Tank 6F some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The isotopes whose detection limits were not met in all cases included Sn-126, Sb-126, Sb-126m, Eu-152, Cm-243 and Cf-249. SRNL, in conjunction with the customer, reviewed all of these cases and determined that the impacts of not meeting the target detection limits were acceptable. Based on the analyses of variance (ANOVA) for the inorganic constituents of Tank 6F, all the inorganic constituents displayed heterogeneity. The inorganic results demonstrated consistent differences across the composite samples: lowest concentrations for Composite Sample 1, intermediate-valued concentrations for Composite

  2. Analysis of the Tank 6F Final Characterization Samples-2012

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L. N.; Diprete, D. P.; Coleman, C. J.; Hay, M. S.; Shine, E. P.

    2013-01-31

    The Savannah River National Laboratory (SRNL) was requested by Savannah River Remediation (SRR) to provide sample preparation and analysis of the Tank 6F final characterization samples to determine the residual tank inventory prior to grouting. Fourteen residual Tank 6F solid samples from three areas on the floor of the tank were collected and delivered to SRNL between May and August 2011. These Tank 6F samples were homogenized and combined into three composite samples based on a proportion compositing scheme and the resulting composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 6F composite samples include bulk density and water leaching of the solids to account for water soluble components. The composite Tank 6F samples were analyzed and the data reported in triplicate. Sufficient quality assurance standards and blanks were utilized to demonstrate adequate characterization of the Tank 6F samples. The main evaluation criteria were target detection limits specified in the technical task request document. While many of the target detection limits were met for the species characterized for Tank 6F some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The isotopes whose detection limits were not met in all cases included Sn-126, Sb-126, Sb-126m, Eu-152, Cm- 243 and Cf-249. SRNL, in conjunction with the customer, reviewed all of these cases and determined that the impacts of not meeting the target detection limits were acceptable. Based on the analyses of variance (ANOVA) for the inorganic constituents of Tank 6F, all the inorganic constituents displayed heterogeneity. The inorganic results demonstrated consistent differences across the composite samples: lowest concentrations for Composite Sample 1, intermediate-valued concentrations for Composite

  3. ANALYSIS OF THE TANK 5F FINAL CHARACTERIZATION SAMPLES-2011

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L.; Diprete, D.; Coleman, C.; Hay, M.

    2012-08-03

    The Savannah River National Laboratory (SRNL) was requested by SRR to provide sample preparation and analysis of the Tank 5F final characterization samples to determine the residual tank inventory prior to grouting. Two types of samples were collected and delivered to SRNL: floor samples across the tank and subsurface samples from mounds near risers 1 and 5 of Tank 5F. These samples were taken from Tank 5F between January and March 2011. These samples from individual locations in the tank (nine floor samples and six mound Tank 5F samples) were each homogenized and combined in a given proportion into 3 distinct composite samples to mimic the average composition in the entire tank. These Tank 5F composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 5F composite samples include bulk density and water leaching of the solids to account for water soluble species. With analyses for certain challenging radionuclides as the exception, all composite Tank 5F samples were analyzed and reported in triplicate. The target detection limits for isotopes analyzed were based on customer desired detection limits as specified in the technical task request documents. SRNL developed new methodologies to meet these target detection limits and provide data for the extensive suite of components. While many of the target detection limits were met for the species characterized for Tank 5F, as specified in the technical task request, some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The Technical Task Request allows that while the analyses of these isotopes is needed, meeting the detection limits for these isotopes is a lower priority than meeting detection limits for the other specified isotopes. The isotopes whose detection limits were not met in all cases included the

  4. Analysis Of The Tank 5F Final Characterization Samples-2011

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L. N.; Diprete, D.; Coleman, C. J.; Hay, M. S.

    2012-09-27

    The Savannah River National Laboratory (SRNL) was requested by SRR to provide sample preparation and analysis of the Tank 5F final characterization samples to determine the residual tank inventory prior to grouting. Two types of samples were collected and delivered to SRNL: floor samples across the tank and subsurface samples from mounds near risers 1 and 5 of Tank 5F. These samples were taken from Tank 5F between January and March 2011. These samples from individual locations in the tank (nine floor samples and six mound Tank 5F samples) were each homogenized and combined in a given proportion into 3 distinct composite samples to mimic the average composition in the entire tank. These Tank 5F composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 5F composite samples include bulk density and water leaching of the solids to account for water soluble species. With analyses for certain challenging radionuclides as the exception, all composite Tank 5F samples were analyzed and reported in triplicate. The target detection limits for isotopes analyzed were based on customer desired detection limits as specified in the technical task request documents. SRNL developed new methodologies to meet these target detection limits and provide data for the extensive suite of components. While many of the target detection limits were met for the species characterized for Tank 5F, as specified in the technical task request, some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The Technical Task Request allows that while the analyses of these isotopes is needed, meeting the detection limits for these isotopes is a lower priority than meeting detection limits for the other specified isotopes. The isotopes whose detection limits were not met in all cases included the

  5. Analysis Of The Tank 6F Final Characterization Samples-2012

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L. N.; Diprete, D. P.; Coleman, C. J.; Hay, M. S.; Shine, E. P.

    2012-09-27

    The Savannah River National Laboratory (SRNL) was requested by Savannah River Remediation (SRR) to provide sample preparation and analysis of the Tank 6F final characterization samples to determine the residual tank inventory prior to grouting. Fourteen residual Tank 6F solid samples from three areas on the floor of the tank were collected and delivered to SRNL between May and August 2011. These Tank 6F samples were homogenized and combined into three composite samples based on a proportion compositing scheme and the resulting composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 6F composite samples include bulk density and water leaching of the solids to account for water soluble components. The composite Tank 6F samples were analyzed and the data reported in triplicate. Sufficient quality assurance standards and blanks were utilized to demonstrate adequate characterization of the Tank 6F samples. The main evaluation criteria were target detection limits specified in the technical task request document. While many of the target detection limits were met for the species characterized for Tank 6F some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The isotopes whose detection limits were not met in all cases included Sn-126, Sb-126, Sb-126m, Eu-152, Cm-243 and Cf-249. SRNL, in conjunction with the customer, reviewed all of these cases and determined that the impacts of not meeting the target detection limits were acceptable. Based on the analyses of variance (ANOVA) for the inorganic constituents of Tank 6F, all the inorganic constituents displayed heterogeneity. The inorganic results demonstrated consistent differences across the composite samples: lowest concentrations for Composite Sample 1, intermediate-valued concentrations for Composite

  6. ANALYSIS OF THE TANK 5F FINAL CHARATERIZATION SAMPLES-2011

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L.; Diprete, D.; Coleman, C.; Hay, M.

    2012-01-20

    The Savannah River National Laboratory (SRNL) was requested by SRR to provide sample preparation and analysis of the Tank 5F final characterization samples to determine the residual tank inventory prior to grouting. Two types of samples were collected and delivered to SRNL: floor samples across the tank and subsurface samples from mounds near risers 1 and 5 of Tank 5F. These samples were taken from Tank 5F between January and March 2011. These samples from individual locations in the tank (nine floor samples and six mound Tank 5F samples) were each homogenized and combined in a given proportion into 3 distinct composite samples to mimic the average composition in the entire tank. These Tank 5F composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 5F composite samples include bulk density and water leaching of the solids to account for water soluble species. With analyses for certain challenging radionuclides as the exception, all composite Tank 5F samples were analyzed and reported in triplicate. The target detection limits for isotopes analyzed were based on customer desired detection limits as specified in the technical task request documents. SRNL developed new methodologies to meet these target detection limits and provide data for the extensive suite of components. While many of the target detection limits were met for the species characterized for Tank 5F, as specified in the technical task request, some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The Technical Task Request allows that while the analyses of these isotopes is needed, meeting the detection limits for these isotopes is a lower priority than meeting detection limits for the other specified isotopes. The isotopes whose detection limits were not met in all cases included the

  7. Analysis Of The Tank 5F Final Characterization Samples-2011

    International Nuclear Information System (INIS)

    The Savannah River National Laboratory (SRNL) was requested by SRR to provide sample preparation and analysis of the Tank 5F final characterization samples to determine the residual tank inventory prior to grouting. Two types of samples were collected and delivered to SRNL: floor samples across the tank and subsurface samples from mounds near risers 1 and 5 of Tank 5F. These samples were taken from Tank 5F between January and March 2011. These samples from individual locations in the tank (nine floor samples and six mound Tank 5F samples) were each homogenized and combined in a given proportion into 3 distinct composite samples to mimic the average composition in the entire tank. These Tank 5F composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 5F composite samples include bulk density and water leaching of the solids to account for water soluble species. With analyses for certain challenging radionuclides as the exception, all composite Tank 5F samples were analyzed and reported in triplicate. The target detection limits for isotopes analyzed were based on customer desired detection limits as specified in the technical task request documents. SRNL developed new methodologies to meet these target detection limits and provide data for the extensive suite of components. While many of the target detection limits were met for the species characterized for Tank 5F, as specified in the technical task request, some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The Technical Task Request allows that while the analyses of these isotopes is needed, meeting the detection limits for these isotopes is a lower priority than meeting detection limits for the other specified isotopes. The isotopes whose detection limits were not met in all cases included the

  8. Analysis Of The Tank 5F Final Charaterization Samples-2011

    International Nuclear Information System (INIS)

    The Savannah River National Laboratory (SRNL) was requested by SRR to provide sample preparation and analysis of the Tank 5F final characterization samples to determine the residual tank inventory prior to grouting. Two types of samples were collected and delivered to SRNL: floor samples across the tank and subsurface samples from mounds near risers 1 and 5 of Tank 5F. These samples were taken from Tank 5F between January and March 2011. These samples from individual locations in the tank (nine floor samples and six mound Tank 5F samples) were each homogenized and combined in a given proportion into 3 distinct composite samples to mimic the average composition in the entire tank. These Tank 5F composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 5F composite samples include bulk density and water leaching of the solids to account for water soluble species. With analyses for certain challenging radionuclides as the exception, all composite Tank 5F samples were analyzed and reported in triplicate. The target detection limits for isotopes analyzed were based on customer desired detection limits as specified in the technical task request documents. SRNL developed new methodologies to meet these target detection limits and provide data for the extensive suite of components. While many of the target detection limits were met for the species characterized for Tank 5F, as specified in the technical task request, some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The Technical Task Request allows that while the analyses of these isotopes is needed, meeting the detection limits for these isotopes is a lower priority than meeting detection limits for the other specified isotopes. The isotopes whose detection limits were not met in all cases included the

  9. Analysis Of The Tank 5F Final Characterization Samples-2011

    International Nuclear Information System (INIS)

    The Savannah River National Laboratory (SRNL) was requested by SRR to provide sample preparation and analysis of the Tank 5F final characterization samples to determine the residual tank inventory prior to grouting. Two types of samples were collected and delivered to SRNL: floor samples across the tank and subsurface samples from mounds near risers 1 and 5 of Tank 5F. These samples were taken from Tank 5F between January and March 2011. These samples from individual locations in the tank (nine floor samples and six mound Tank 5F samples) were each homogenized and combined in a given proportion into 3 distinct composite samples to mimic the average composition in the entire tank. These Tank 5F composite samples were analyzed for radiological, chemical and elemental components. Additional measurements performed on the Tank 5F composite samples include bulk density and water leaching of the solids to account for water soluble species. With analyses for certain challenging radionuclides as the exception, all composite Tank 5F samples were analyzed and reported in triplicate. The target detection limits for isotopes analyzed were based on customer desired detection limits as specified in the technical task request documents. SRNL developed new methodologies to meet these target detection limits and provide data for the extensive suite of components. While many of the target detection limits were met for the species characterized for Tank 5F, as specified in the technical task request, some were not met. In a few cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. The Technical Task Request allows that while the analyses of these isotopes is needed, meeting the detection limits for these isotopes is a lower priority than meeting detection limits for the other specified isotopes. The isotopes whose detection limits were not met in all cases included the

  10. Recent progresses in experimental investigation and finite element analysis of ratcheting in pressurized piping

    International Nuclear Information System (INIS)

    This article presents an overview of recent progresses in experimental investigation and finite element analysis (FEA) of ratcheting behavior of pressurized piping. Ratcheting, namely the cyclic accumulation of plastic deformation, occurs when the structures are subjected to a primary load with a secondary cyclic load if the applied loads are high enough to make the structures yield. Typical piping structures including straight pipes, elbow pipes and piping joints have been investigated experimentally under mechanical or thermal cyclic loading. Finite element analyses with several well-developed constitutive models implemented in the commercial software ANSYS and ABAQUS have been conducted to simulate and predict the ratcheting behavior of pressurized piping. Based on such experimental and FEA research, ratcheting boundaries have been determined with the final aim of aiding the safety design and assessment of engineering piping structures. Some suggestions for structure ratcheting study are proposed. Highlights: ► Researches on ratcheting behavior of pressurized piping components are reviewed. ► FE implementation of unified Armstrong–Frederic type models is introduced. ► FE analyses on ratcheting behavior and boundary of pressurized piping are discussed.

  11. Analysis for the Progressive Failure Response of Textile Composite Fuselage Frames

    Science.gov (United States)

    Johnson, Eric R.; Boitnott, Richard L. (Technical Monitor)

    2002-01-01

    A part of aviation accident mitigation is a crashworthy airframe structure, and an important measure of merit for a crashworthy structure is the amount of kinetic energy that can be absorbed in the crush of the structure. Prediction of the energy absorbed from finite element analyses requires modeling the progressive failure sequence. Progressive failure modes may include material degradation, fracture and crack growth, and buckling and collapse. The design of crashworthy airframe components will benefit from progressive failure analyses that have been validated by tests. The subject of this research is the development of a progressive failure analysis for a textile composite, circumferential fuselage frame subjected to a quasi-static, crash-type load. The test data for the frame are reported, and these data are used to develop and to validate methods for the progressive failure response.

  12. Peak and ceiling effects in final-product analysis of mastoidectomy performance

    DEFF Research Database (Denmark)

    West, N; Konge, L; Cayé-Thomasen, P;

    2015-01-01

    BACKGROUND: Virtual reality surgical simulation of mastoidectomy is a promising training tool for novices. Final-product analysis for assessing novice mastoidectomy performance could be limited by a peak or ceiling effect. These may be countered by simulator-integrated tutoring. METHODS: Twenty-t...... instruction is important when using final-product analysis to assess novice mastoidectomy performance. Improved real-time feedback and tutoring could address the limitations of final product based assessment....

  13. Research progress of operational transfer path analysis method

    Directory of Open Access Journals (Sweden)

    Yingying LU

    2015-08-01

    Full Text Available Firstly, the basic principles, the advantages, the disadvantages and the engineering applications of the conventional TPA, OTPA, OPAX and mixed TPA in recent years are comprehensively analyzed. Meanwhile, the potential applications of power flow in the TPA field are especially discussed. Secondly, focused on the OTPA method, an acoustic transfer path system by spherical radiation transfer path simulation system and a vibration transfer path experiment system by a rectangular plate vibrator excitation are designed considering the effects of the distance from reference points. The results show that the relative error between the OTPA values and the theoretical values as well as the experimental values is less than 5% and 8% respectively. At the same time, OTPA is sensitive to noise. When the noise is lower, the nearer reference points can improve the precision of OTPA method. Therefore, it is needed to arrange sensors and design operating conditions reasonably. Finally, the development trend of TPA method is presented.

  14. Progress in fusion reactors blanket analysis and evaluation at CEA

    International Nuclear Information System (INIS)

    In the frame of the recent CEA studies aiming at the development, evaluation and comparison of solid breeder blanket concepts in view of their adaptation to NET, and the evaluation of specific questions related to the first wall design, the present paper examines first the performances of a helium cooled toroidal blanket design for NET, based on innovative Beryllium/Ceramics breeder rod elements. Neutronic and thermo-mechanical optimisation converges on a concept featured by a breeding capability in excess of 1.2, a reasonnable pumping power of 1 % and a narrow breeder temperature range (470 +- 30 0C of the breeder), the latter being largely independent of the power level. The final section of the paper is devoted to the evaluation of the heat load poloidal distribution and to the irradiation effects on first wall structural materials

  15. Demonstration Technology Application and Analysis on the Scientific and Technological Progress

    OpenAIRE

    Qingzhu Qi; Zhixiao Jiang

    2013-01-01

    This paper takes Tianjin for example and analyzes the development tend of scientific and technological progress in Tianjin. From five aspects as ‘environment of scientific and technological progress’, ‘input of scientific and technological activities’, ‘output of scientific and technological activities’, ‘high-tech industrialization’, ‘science and technology for economic and social development’, the paper analysis the correlation between GDP and scientific and technological progress. Research...

  16. Analysis of genetic copy number changes in cervical disease progression

    International Nuclear Information System (INIS)

    Cervical dysplasia and tumorigenesis have been linked with numerous chromosomal aberrations. The goal of this study was to evaluate 35 genomic regions associated with cervical disease and to select those which were found to have the highest frequency of aberration for use as probes in fluorescent in-situ hybridization. The frequency of gains and losses using fluorescence in-situ hybridization were assessed in these 35 regions on 30 paraffin-embedded cervical biopsy specimens. Based on this assessment, 6 candidate fluorescently labeled probes (8q24, Xp22, 20q13, 3p14, 3q26, CEP15) were selected for additional testing on a set of 106 cervical biopsy specimens diagnosed as Normal, CIN1, CIN2, CIN3, and SCC. The data were analyzed on the basis of signal mean, % change of signal mean between histological categories, and % positivity. The study revealed that the chromosomal regions with the highest frequency of copy number gains and highest combined sensitivity and specificity in high-grade cervical disease were 8q24 and 3q26. The cytological application of these two probes was then evaluated on 118 ThinPrep™ samples diagnosed as Normal, ASCUS, LSIL, HSIL and Cancer to determine utility as a tool for less invasive screening. Using gains of either 8q24 or 3q26 as a positivity criterion yielded specificity (Normal +LSIL+ASCUS) of 81.0% and sensitivity (HSIL+Cancer) of 92.3% based on a threshold of 4 positive cells. The application of a FISH assay comprised of chromosomal probes 8q24 and 3q26 to cervical cytology specimens confirms the positive correlation between increasing dysplasia and copy gains and shows promise as a marker in cervical disease progression

  17. Progressive-Ratio Schedules and Applied Behavior Analysis

    Science.gov (United States)

    Poling, Alan

    2010-01-01

    Establishing appropriate relations between the basic and applied areas of behavior analysis has been of long and persistent interest to the author. In this article, the author illustrates that there is a direct relation between how hard an organism will work for access to an object or activity, as indexed by the largest ratio completed under a…

  18. Progress in fusion reactors blanket analysis and evaluation at CEA

    International Nuclear Information System (INIS)

    In the frame of the recent CEA studies aiming at the development, evaluation and comparison of solid breeder blanket concepts in view of their adaptation to NET, the evaluation of specific questions related to the first wall design, the present paper examines first the performances of a helium cooled toroidal blanket design for NET, based on innovative Beryllium/Ceramics breeder rod elements. Neutronic and thermo-mechanical optimisation converges on a concept featured by a breeding capability in excess of 1.2, a reasonnable pumping power of 1% and a narrow breeder temperature range (470+-30 deg C of the breeder), the latter being largely independent of the power level. This design proves naturally adapted to ceramic breeder assigned to very strict working conditions, and provides for any change in the thermal and heat transfer characteristics over the blanket lifetime. The final section of the paper is devoted to the evaluation of the heat load poloidal distribution and to the irradiation effects on first wall structural materials

  19. Recent progress on HYSPEC, and its polarization analysis capabilities

    Directory of Open Access Journals (Sweden)

    Winn Barry

    2015-01-01

    Full Text Available HYSPEC is a high-intensity, direct-geometry time-of-flight spectrometer at the Spallation Neutron Source, optimized for measurement of excitations in small single-crystal specimens with optional polarization analysis capabilities. The incident neutron beam is monochromated using a Fermi chopper with short, straight blades, and is then vertically focused by Bragg scattering onto the sample position by either a highly oriented pyrolitic graphite (unpolarized or a Heusler (polarized crystal array. Neutrons are detected by a bank of 3He tubes that can be positioned over a wide range of scattering angles about the sample axis. HYSPEC entered the user program in February 2013 for unpolarized experiments, and is already experiencing a vibrant research program. Polarization analysis will be accomplished by using the Heusler crystal array to polarize the incident beam, and either a 3He spin filter or a supermirror wide-angle polarization analyser to analyse the scattered beam. The 3He spin filter employs the spin-exchange optical pumping technique. A 60∘ wide angle 3He cell that matches the detector coverage will be used for polarization analysis. The polarized gas in the post-sample wide angle cell is designed to be periodically and automatically refreshed with an adjustable pressure of polarized gas, optically pumped in a separate cell and then transferred to the wide angle cell. The supermirror analyser has 960 supermirror polarizers distributed over 60∘, and has been characterized at the Swiss Spallation Neutron Source. The current status of the instrument and the development of its polarization analysis capabilities are presented.

  20. PROGRESS IN SIFT-MS: BREATH ANALYSIS AND OTHER APPLICATIONS

    Czech Academy of Sciences Publication Activity Database

    Španěl, Patrik; Smith, D.

    2011-01-01

    Roč. 30, č. 2 (2011), s. 236-267. ISSN 0277-7037 R&D Projects: GA MPO FT-TA4/124; GA ČR GA202/09/0800; GA ČR GA203/09/0256 Institutional research plan: CEZ:AV0Z40400503 Keywords : SIFT-MS * breath analysis * ion flow tube Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 10.461, year: 2011

  1. Utility guidelines for reactor noise analysis: Final report

    International Nuclear Information System (INIS)

    Noise analysis techniques have been extensively utilized to monitor the health and performance of nuclear power plant systems. However, few utilities have adequate programs to effectively utilize these techniques. These programs usually provide low-quality data, which can lead to misinterpretation and false alarms. The objective of this work is to provide utilities and noise analysts with guidelines for data acquisition, data analysis, and interpretation of noise analysis results for surveillance and diagnosis of reactor systems

  2. Progress on Radiochemical Analysis for Nuclear Waste Management in Decommissioning

    DEFF Research Database (Denmark)

    Hou, Xiaolin; Qiao, Jixin; Shi, Keliang;

    With the increaed numbers of nuclear facilities have been closed and are being or are going to be decommissioned, it is required to characterise the produced nuclear waste for its treatment by identification of the radionuclides and qualitatively determine them. Of the radionuclides related...... separation of radionuclides. In order to improve and maintain the Nodic competence in analysis of radionculides in waste samples, a NKS B project on this topic was launched in 2009. During the first phase of the NKS-B RadWaste project (2009-2010), a good achivement has been reached on establishment...

  3. Low-dose fractionated radiotherapy and concomitant chemotherapy for recurrent or progressive glioblastoma. Final report of a pilot study

    Energy Technology Data Exchange (ETDEWEB)

    Balducci, M.; Diletto, B.; Chiesa, S.; D' Agostino, G.R.; Gambacorta, M.A.; Ferro, M.; Valentini, V. [Catholic University of the Sacred Heart, Department of Radiation Oncology, Rome (Italy); Colosimo, C. [Catholic University of the Sacred Heart, Department of Radiology, Rome (Italy); Maira, G.; Anile, C. [Catholic University of the Sacred Heart, Department of Neurosurgery, Rome (Italy)

    2014-04-15

    Evaluated in this study were the feasibility and the efficacy of concurrent low dose fractionated radiotherapy (LD-FRT) and chemotherapy as palliative treatment for recurrent/progressive glioblastoma multiforme (GBM). Eligible patients had recurrent or progressive GBM, Karnofsky performance status ≥70, prior surgery, and standard radiochemotherapy treatment. Recurrence/progression disease during temozolomide (TMZ) received cisplatin (CDDP; 30 mg/m{sup 2} on days 1, 8, 15), fotemustine (FTM; 40 mg/m{sup 2} on days 2, 9, 16), and concurrent LD-FRT (0.3 Gy twice daily); recurrence/progression after 4 months from the end of adjuvant TMZ were treated by TMZ (150/200 mg/m{sup 2} on days 1-5) concomitant with LD-FRT (0.4 Gy twice daily). Primary endpoints were safety and toxicity. A total of 32 patients were enrolled. Hematologic toxicity G1-2 was observed in 18.7% of patients and G3-4 in 9.4%. One patient (3.1%) had complete response, 3 (9.4%) had partial response, 8 (25%) had stable disease for at least 8 weeks, while 20 patients (62.5%) experienced progressive disease. The clinical benefit was 37.5%. Median progression-free survival (PFS) and overall survival (OS) were 5 and 8 months, respectively. Survival rate at 12 months was of 27.8%. LD-FRT and chemotherapy for recurrent/progressive GBM have a good toxicity profile and clinical outcomes, even though further investigation of this novel palliative treatment approach is warranted. (orig.)

  4. Progress Toward Efficient Laminar Flow Analysis and Design

    Science.gov (United States)

    Campbell, Richard L.; Campbell, Matthew L.; Streit, Thomas

    2011-01-01

    A multi-fidelity system of computer codes for the analysis and design of vehicles having extensive areas of laminar flow is under development at the NASA Langley Research Center. The overall approach consists of the loose coupling of a flow solver, a transition prediction method and a design module using shell scripts, along with interface modules to prepare the input for each method. This approach allows the user to select the flow solver and transition prediction module, as well as run mode for each code, based on the fidelity most compatible with the problem and available resources. The design module can be any method that designs to a specified target pressure distribution. In addition to the interface modules, two new components have been developed: 1) an efficient, empirical transition prediction module (MATTC) that provides n-factor growth distributions without requiring boundary layer information; and 2) an automated target pressure generation code (ATPG) that develops a target pressure distribution that meets a variety of flow and geometry constraints. The ATPG code also includes empirical estimates of several drag components to allow the optimization of the target pressure distribution. The current system has been developed for the design of subsonic and transonic airfoils and wings, but may be extendable to other speed ranges and components. Several analysis and design examples are included to demonstrate the current capabilities of the system.

  5. Gender-Based Analysis On-Line Dialogue. Final Report.

    Science.gov (United States)

    2001

    An online dialogue on gender-based analysis (GBA) was held from February 15 to March 7, 2001. Invitations and a background paper titled "Why Gender-Based Analysis?" were sent to 350 women's organizations and individuals throughout Canada. Efforts were made to ensure that aboriginal and Metis women, visible minority women, and women with special…

  6. Neutron activation analysis of final molasses from cuban sugar industry

    International Nuclear Information System (INIS)

    Thermal and epithermal non-destructive activation analyses have been performed on samples of final molasses from 14 different sugar factories , covering the most important regions in Cuba. From the first measurement after irradiation at the Triga Mark reactor (VTT), the concentration of more than 15 elements is reported. The almost constant elemental composition shows that they can be used equally for different purposes as animal foodstuff and for the manufacture of biotechnological products. This work is part of a research project developed in order to establish a complete characterization of Cuban sugar molasses. (author). 7 refs., 2 tabs

  7. Joint application of AI techniques, PRA and disturbance analysis methodology to problems in the maintenance and design of nuclear power plants. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Okrent, D.

    1989-03-01

    This final report summarizes the accomplishments of a two year research project entitled ``Joint Application of Artificial Intelligence Techniques, Probabilistic Risk Analysis, and Disturbance Analysis Methodology to Problems in the Maintenance and Design of Nuclear Power Plants. The objective of this project is to develop and apply appropriate combinations of techniques from artificial intelligence, (AI), reliability and risk analysis and disturbance analysis to well-defined programmatic problems of nuclear power plants. Reactor operations issues were added to those of design and maintenance as the project progressed.

  8. Instrumental neutron activation analysis of archaeological ceramics: Progress and challenges

    International Nuclear Information System (INIS)

    Instrumental neutron activation analysis (INAA) has become a widely used technique in the characterization of archaeological ceramics. Early applications, primarily developmental in nature, have been replaced by studies that attempt to place the derived analytical data in a larger archaeological and behavioural context. If archaeology is to increasingly exploit the great potential of INAA to address a broad range of social and cultural issues involving ceramics, greater attention must be paid to the various sources of variation that contribute to the chemical composition of pottery. In addition, as all research takes place within a social context, efforts must be made to increase the communication between archaeologists and other scientists, as this will contribute to the fulfilment of the archaeological research objectives. (author)

  9. Evaluation of Progressive Failure Analysis and Modeling of Impact Damage in Composite Pressure Vessels

    Science.gov (United States)

    Sanchez, Christopher M.

    2011-01-01

    NASA White Sands Test Facility (WSTF) is leading an evaluation effort in advanced destructive and nondestructive testing of composite pressure vessels and structures. WSTF is using progressive finite element analysis methods for test design and for confirmation of composite pressure vessel performance. Using composite finite element analysis models and failure theories tested in the World-Wide Failure Exercise, WSTF is able to estimate the static strength of composite pressure vessels. Additionally, test and evaluation on composites that have been impact damaged is in progress so that models can be developed to estimate damage tolerance and the degradation in static strength.

  10. The oncogenic action of ionizing radiation on rat skin. Final progress report, May 1, 1990--April 30, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Burns, F.J.; Garte, S.J.

    1992-12-31

    The multistage theory of carcinogenesis specifies that cells progress to cancer through a series of discrete, irreversible genetic alterations, but data on radiation-induced cancer incidence in rat skin suggests that an intermediate repairable alteration may occur. Data are presented on cancer induction in rat skin exposed to an electron beam (LET=0.34 keV/{mu}), a neon ion beam (LET=45) or an argon ion beam (LET=125). The rats were observed for tumors at least 78 weeks with squamous and basal cell carcinomas observed. The total cancer yield was fitted by the quadratic equation, and the equation parameters were estimated by linear regression for each type of radiation. Analysis of the DNA from the electron-induced carcinomas indicated that K-ras and/or c-myc oncogenes were activated. In situ hybridization indicated that the cancers contain subpopulations of cells with differing amounts of c-myc and H-ras amplification. The results are consistent with the idea that ionizing radiation produces stable, carcinogenically relevant lesions via 2 repairable events at low LET and via a non-repairable linked event pathway at high LET; either pathway may advance the cell by 1 stage. The proliferative response of rat epidermis following exposure to ionizing radiation was quantified by injection of {sup 14}C-thymidine. The return of these cells to S-phase a second time was detected by a second label ({sup 3}H). When the labeled cells were in G1-phase, the dorsal skin was irradiated with X-rays. All labeling indices were determined. The {sup 14}C labeling index was constant and unaffected by the radiation. The proportion of all cells entering S-phase averaged 3.5% at 18 hr and increased after 44, 52 and 75 hr to average levels of 11.8%, 5. 3%, and 6.6% at 0, 10 and 25 Gy respectively. The proportion of S-phase cells labeled with {sup 14}C increased after 42 hr and remained relatively constant thereafter.

  11. Photovoltaic venture analysis. Final report. Volume III. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Costello, D.; Posner, D.; Schiffel, D.; Doane, J.; Bishop, C.

    1978-07-01

    This appendix contains a brief summary of a detailed description of alternative future energy scenarios which provide an overall backdrop for the photovoltaic venture analysis. Also included is a summary of a photovoltaic market/demand workshop, a summary of a photovoltaic supply workshop which used cross-impact analysis, and a report on photovoltaic array and system prices in 1982 and 1986. The results of a sectorial demand analysis for photovoltaic power systems used in the residential sector (single family homes), the service, commercial, and institutional sector (schools), and in the central power sector are presented. An analysis of photovoltaics in the electric utility market is given, and a report on the industrialization of photovoltaic systems is included. A DOE information memorandum regarding ''A Strategy for a Multi-Year Procurement Initiative on Photovoltaics (ACTS No. ET-002)'' is also included. (WHK)

  12. Development of a risk-analysis model. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1979-10-01

    This report consists of a main body, which provides a presentation of risk analysis and its general and specific application to the needs of the Office of Buildings and Community Systems of the Department of Energy; and several case studies employing the risk-analysis model developed. The highlights include a discussion of how risk analysis is currently used in the private, regulated, and public sectors and how this methodology can be employed to meet the policy-analysis needs of the Office of Buildings and Community Systems of the Department of Energy (BCS/DOE). After a review of the primary methodologies available for risk analysis, it was determined that Monte Carlo simulation techniques provide the greatest degree of visibility into uncertainty in the decision-making process. Although the data-collection requirements can be demanding, the benefits, when compared to other methods, are substantial. The data-collection problem can be significantly reduced, without sacrificing proprietary-information rights, if prior arrangements are made with RD and D contractors to provide responses to reasonable requests for base-case data. A total of three case studies were performed on BCS technologies: a gas-fired heat pump; a 1000 ton/day anaerobic digestion plant; and a district heating and cooling system. The three case studies plus the risk-analysis methodology were issued as separate reports. It is concluded that, based on the overall research of risk analysis and the case-study experience, that the risk-analysis methodology has significant potential as a policy-evaluation tool within BCS.

  13. Accident progression event tree analysis for postulated severe accidents at N Reactor

    International Nuclear Information System (INIS)

    A Level II/III probabilistic risk assessment (PRA) has been performed for N Reactor, a Department of Energy (DOE) production reactor located on the Hanford reservation in Washington. The accident progression analysis documented in this report determines how core damage accidents identified in the Level I PRA progress from fuel damage to confinement response and potential releases the environment. The objectives of the study are to generate accident progression data for the Level II/III PRA source term model and to identify changes that could improve plant response under accident conditions. The scope of the analysis is comprehensive, excluding only sabotage and operator errors of commission. State-of-the-art methodology is employed based largely on the methods developed by Sandia for the US Nuclear Regulatory Commission in support of the NUREG-1150 study. The accident progression model allows complex interactions and dependencies between systems to be explicitly considered. Latin Hypecube sampling was used to assess the phenomenological and systemic uncertainties associated with the primary and confinement system responses to the core damage accident. The results of the analysis show that the N Reactor confinement concept provides significant radiological protection for most of the accident progression pathways studied

  14. 40 CFR 60.1585 - What are my requirements for meeting increments of progress and achieving final compliance?

    Science.gov (United States)

    2010-07-01

    ... SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on... construction. (4) Complete onsite construction. (5) Achieve final compliance. (b) Class II units. If you...

  15. Progression Analysis and Stage Discovery in Continuous Physiological Processes Using Image Computing

    Directory of Open Access Journals (Sweden)

    Ferrucci Luigi

    2010-01-01

    Full Text Available We propose an image computing-based method for quantitative analysis of continuous physiological processes that can be sensed by medical imaging and demonstrate its application to the analysis of morphological alterations of the bone structure, which correlate with the progression of osteoarthritis (OA. The purpose of the analysis is to quantitatively estimate OA progression in a fashion that can assist in understanding the pathophysiology of the disease. Ultimately, the texture analysis will be able to provide an alternative OA scoring method, which can potentially reflect the progression of the disease in a more direct fashion compared to the existing clinically utilized classification schemes based on radiology. This method can be useful not just for studying the nature of OA, but also for developing and testing the effect of drugs and treatments. While in this paper we demonstrate the application of the method to osteoarthritis, its generality makes it suitable for the analysis of other progressive clinical conditions that can be diagnosed and prognosed by using medical imaging.

  16. Glaucoma Progression Detection by Retinal Nerve Fiber Layer Measurement Using Scanning Laser Polarimetry: Event and Trend Analysis

    OpenAIRE

    Moon, Byung Gil; Sung, Kyung Rim; Cho, Jung Woo; Kang, Sung Yong; Yun, Sung-Cheol; Na, Jung Hwa; Lee, Youngrok; Kook, Michael S.

    2012-01-01

    Purpose To evaluate the use of scanning laser polarimetry (SLP, GDx VCC) to measure the retinal nerve fiber layer (RNFL) thickness in order to evaluate the progression of glaucoma. Methods Test-retest measurement variability was determined in 47 glaucomatous eyes. One eye each from 152 glaucomatous patients with at least 4 years of follow-up was enrolled. Visual field (VF) loss progression was determined by both event analysis (EA, Humphrey guided progression analysis) and trend analysis (TA,...

  17. Photovoltaic venture analysis. Final report. Volume II. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Costello, D.; Posner, D.; Schiffel, D.; Doane, J.; Bishop, C.

    1978-07-01

    A description of the integrating model for photovoltaic venture analysis is given; input assumptions for the model are described; and the integrating model program listing is given. The integrating model is an explicit representation of the interactions between photovoltaic markets and supply under alternative sets of assumptions. It provides a consistent way of assembling and integrating the various assumptions, data, and information that have been obtained on photovoltaic systems supply and demand factors. Secondly, it provides a mechanism for understanding the implications of all the interacting assumptions. By representing the assumptions in a common, explicit framework, much more complex interactions can be considered than are possible intuitively. The integrating model therefore provides a way of examining the relative importance of different assumptions, parameters, and inputs through sensitivity analysis. Also, detailed results of model sensitivity analysis and detailed market and systems information are presented. (WHK)

  18. 10 CFR 52.79 - Contents of applications; technical information in final safety analysis report.

    Science.gov (United States)

    2010-01-01

    ...; technical information in final safety analysis report. (a) The application must contain a final safety... CFR part 50, appendix A, GDC 3, and § 50.48 of this chapter; (7) A description of protection provided... important to safety and the list of electric equipment important to safety that is required by 10 CFR...

  19. Photovoltaic venture analysis. Final report. Volume I. Executive summary

    Energy Technology Data Exchange (ETDEWEB)

    Costello, D.; Posner, D.; Schiffel, D.; Doane, J.; Bishop, C.

    1978-07-01

    The objective of the study, government programs under investigation, and a brief review of the approach are presented. Potential markets for photovoltaic systems relevant to the study are described. The response of the photovoltaic supply industry is then considered. A model which integrates the supply and demand characteristics of photovoltaics over time was developed. This model also calculates the economic benefits associated with various government subsidy programs. Results are derived under alternative possible supply, demand, and macroeconomic conditions. A probabilistic analysis of the costs and benefits of a $380 million federal photovoltaic procurement initiative, as well as certain alternative strategies, is summarized. Conclusions and recommendations based on the analysis are presented.

  20. Neutron activation analysis of final molasses from the sugar industry

    International Nuclear Information System (INIS)

    Molasses samples from 74 factories were analyzed by neutron activation analysis. The concentration values of the 35 elements was determined. The toxicity and the influence of the presence of theses elements in sugar loss in the molasses and fermentative process is discussed

  1. Fast flux test facility final safety analysis report amendment 79

    International Nuclear Information System (INIS)

    This document is provided to replace, remove, or add applicable pages to the chapters on: Heat Transport System; Containment and Structures; Auxiliary Systems; Reactor Refueling System; Conduct of Operations; Safety Analysis; Quality Assurance; FFTF Criticality Specifications; and Appendix H's TRIGA Fuel Storage System

  2. Progress Towards Improved Analysis of TES X-ray Data Using Principal Component Analysis

    Science.gov (United States)

    Busch, S. E.; Adams, J. S.; Bandler, S. R.; Chervenak, J. A.; Eckart, M. E.; Finkbeiner, F. M.; Fixsen, D. J.; Kelley, R. L.; Kilbourne, C. A.; Lee, S.-J.; Moseley, S. H.; Porst, J.-P.; Porter, F. S.; Sadleir, J. E.; Smith, S. J.

    2016-07-01

    The traditional method of applying a digital optimal filter to measure X-ray pulses from transition-edge sensor (TES) devices does not achieve the best energy resolution when the signals have a highly non-linear response to energy, or the noise is non-stationary during the pulse. We present an implementation of a method to analyze X-ray data from TESs, which is based upon principal component analysis (PCA). Our method separates the X-ray signal pulse into orthogonal components that have the largest variance. We typically recover pulse height, arrival time, differences in pulse shape, and the variation of pulse height with detector temperature. These components can then be combined to form a representation of pulse energy. An added value of this method is that by reporting information on more descriptive parameters (as opposed to a single number representing energy), we generate a much more complete picture of the pulse received. Here we report on progress in developing this technique for future implementation on X-ray telescopes. We used an ^{55}Fe source to characterize Mo/Au TESs. On the same dataset, the PCA method recovers a spectral resolution that is better by a factor of two than achievable with digital optimal filters.

  3. Final Technical Progress Report; Closeout Certifications; CSSV Newsletter Volume I; CSSV Newsletter Volume II; CSSV Activity Journal; CSSV Final Financial Report

    Energy Technology Data Exchange (ETDEWEB)

    Houston, Johnny L [PI; Geter, Kerry [Division of Business and Finance

    2013-08-23

    This Project?s third year of implementation in 2007-2008, the final year, as designated by Elizabeth City State University (ECSU), in cooperation with the National Association of Mathematicians (NAM) Inc., in an effort to promote research and research training programs in computational science ? scientific visualization (CSSV). A major goal of the Project was to attract the energetic and productive faculty, graduate and upper division undergraduate students of diverse ethnicities to a program that investigates science and computational science issues of long-term interest to the Department of Energy (DoE) and the nation. The breadth and depth of computational science?scientific visualization and the magnitude of resources available are enormous for permitting a variety of research activities. ECSU?s Computational Science-Science Visualization Center will serve as a conduit for directing users to these enormous resources.

  4. 1985. Annual progress report

    International Nuclear Information System (INIS)

    This annual progress report of the CEA Protection and Nuclear Safety Institut outlines a description of the progress made in each sections of the Institut Research activities of the different departments include: reactor safety analysis, fuel cycle facilities analysis; and associated safety research programs (criticality, sites, transport ...), radioecology and environmental radioprotection techniques; data acquisition on radioactive waste storage sites; radiation effects on man, studies on radioprotection techniques; nuclear material security including security of facilities, security of nuclear material transport, and monitoring of nuclear material management; nuclear facility decommissioning; and finally the public information

  5. Chest x-ray analysis by computer: final technical report

    International Nuclear Information System (INIS)

    The purpose of this study was to evaluate and demonstrate the feasibility of the automated analysis of chest x-rays for the classification of pneumoconiosis films according to the U.I.C.C./Cincinnati standard films. Toward this end, computer programs simulating the proposed systems were prepared. Using these programs, the authors then examined three sets of chest radiographs to determine the extent of pneumoconiosis present. The results of the examinations of these x-rays clearly indicated the feasibility of the proposed system. Based on the outcome of these examinations, a complete set of hardware and software specifications were established for a system which can be used for the large scale automatic analysis of chest x-rays

  6. Vertically integrated analysis of human DNA. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Olson, M.

    1997-10-01

    This project has been oriented toward improving the vertical integration of the sequential steps associated with the large-scale analysis of human DNA. The central focus has been on an approach to the preparation of {open_quotes}sequence-ready{close_quotes} maps, which is referred to as multiple-complete-digest (MCD) mapping, primarily directed at cosmid clones. MCD mapping relies on simple experimental steps, supported by advanced image-analysis and map-assembly software, to produce extremely accurate restriction-site and clone-overlap maps. We believe that MCD mapping is one of the few high-resolution mapping systems that has the potential for high-level automation. Successful automation of this process would be a landmark event in genome analysis. Once other higher organisms, paving the way for cost-effective sequencing of these genomes. Critically, MCD mapping has the potential to provide built-in quality control for sequencing accuracy and to make possible a highly integrated end product even if there are large numbers of discontinuities in the actual sequence.

  7. Final Technical Progress Report: High-Efficiency Low-Cost Thin-Film GaAs Photovoltaic Module Development Program; July 14, 2010 - January 13, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Mattos, L.

    2012-03-01

    This is the final technical progress report of the High-Efficiency Low-Cost Thin-Film GaAs Photovoltaic Module Development Program. Alta Devices has successfully completed all milestones and deliverables established as part of the NREL PV incubator program. During the 18 months of this program, Alta has proven all key processes required to commercialize its solar module product. The incubator focus was on back end process steps directed at conversion of Alta's high quality solar film into high efficiency 1-sun PV modules. This report describes all program deliverables and the work behind each accomplishment.

  8. Methods of economic analysis applied to fusion research. Final report

    International Nuclear Information System (INIS)

    In this and previous efforts ECON has provided economic assessment of a fusion research program. This phase of study focused on two tasks, the first concerned with the economics of fusion in an economy that relies heavily upon synthetic fuels, and the second concerned with the overall economic effects of pursuing soft energy technologies instead of hard technologies. This report is organized in two parts, the first entitled An Economic Analysis of Coproduction of Fusion-Electric Energy and Other Products, and the second entitled Arguments Associated with the Choice of Potential Energy Futures

  9. Analysis of sludge from Indian Point 3. Final report

    International Nuclear Information System (INIS)

    This report describes detailed chemical anlaysis of samples of Indian Point 3 PWR steam generator sludge. The sludge was found to be primarily made of oxides of iron with percentage amounts of copper metal, cuprous oxide, and sand. In addition, Zn, Ni, and Al were observed at the 1 to 2% level. Other elements observed at less than 1% included Mn, Mg, Pb, Ca, B, P, S, Ti, Cr, Zr, Mo, and Sn. An unexpected finding was that it contained 2% of ion exchange resins. Both an anion and a cation resin fraction were separated. Their separation and subsequent analysis is discussed in detail, and the entire set of chemical analyses is described

  10. Aerosol analysis for the regional air pollution study. Final report

    International Nuclear Information System (INIS)

    The design and operation of an aerosol sampling and analysis program implemented during the 1975 to 1977 St. Louis Regional Air Pollution Study is described. A network of ten samplers were operated at selected sites in the St. Louis area and the total mass and elemental composition of the collected particulates were determined. Sampling periods of 2 to 24 hours were employed. The samplers were capable of collecting aerosol particles in two distinct size ranges corresponding to fine ( 2.4 μm diameter) particles. This unique feature allowed the separation of the particulate samples into two distinct fractions with differing chemical origins and health effects. The analysis methods were also newly developed for use in the St. Louis RAPS study. Total particulate mass was measured by a beta-particle attenuation method in which a precision of +- 5 μm/cm2 could be obtained in a one minute measurement time. Elemental compositions of the samples were determined using an energy dispersive x-ray fluorescence method in which detectable limits of 5 ng/cm2 or less were routinely achieved for elements ranging in atomic number from Al to Pb. The advantages of these analytical methods over more conventional techniques arise from the ability to automate the measurements. During the course of the two year study, a total of more than 35,000 individual samples were processed and a total of 28 concentrations measured for each sample

  11. Analysis of Intellectual Capital Effect toward Final Performance and Growt

    Directory of Open Access Journals (Sweden)

    Sasya Sabrina

    2015-11-01

    Full Text Available The purpose of this research is to investigate the influence of intellectual capital of firm toward financial performance and growth. The Value Added Intellectual Coefficient (VAICTM is used to measure intellectual capital. The indicators for VAICTM are Value Added Capital Employed (VACA, Value Added Human Capital (VAHU, and Structural Capital Value Added (STVA. The indicators for financial performance are Current Ratio (CR, Total Assets Turnover (TATO, Return on Investment (ROI, and Return on Equity (ROE. The indicators for growth are Earnings Growth (EG and Assets Growth (AG. This research uses data drawn from 92 publicly listed manufacturing companies in Indonesian Stock Exchange in 2010, 2011, and 2012. Partial Least Square (PLS is used as the method of data analysis. This research uses SmartPLS 3.2.0 to analyze the data.The results show that: intellectual capital doesnt influence financial performance and intellectual capital positively influences growth.

  12. Research on data analysis in the physical sciences. Final progress report, March 1973-November 1979

    Energy Technology Data Exchange (ETDEWEB)

    Tukey, J.W.; Bloomfield, P.

    1979-11-01

    In its most general terms, the work carried out under the contract consists of the development of new data analytic methods and the improvement of existing methods, their implementation on computer, especially minicomputers, and the development of non-statistical, systems-level software to support these activities. The work reported or completed is reviewed. (GHT)

  13. Final Report. Analysis and Reduction of Complex Networks Under Uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Marzouk, Youssef M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Coles, T. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Spantini, A. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Tosatto, L. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2013-09-30

    The project was a collaborative effort among MIT, Sandia National Laboratories (local PI Dr. Habib Najm), the University of Southern California (local PI Prof. Roger Ghanem), and The Johns Hopkins University (local PI Prof. Omar Knio, now at Duke University). Our focus was the analysis and reduction of large-scale dynamical systems emerging from networks of interacting components. Such networks underlie myriad natural and engineered systems. Examples important to DOE include chemical models of energy conversion processes, and elements of national infrastructure—e.g., electric power grids. Time scales in chemical systems span orders of magnitude, while infrastructure networks feature both local and long-distance connectivity, with associated clusters of time scales. These systems also blend continuous and discrete behavior; examples include saturation phenomena in surface chemistry and catalysis, and switching in electrical networks. Reducing size and stiffness is essential to tractable and predictive simulation of these systems. Computational singular perturbation (CSP) has been effectively used to identify and decouple dynamics at disparate time scales in chemical systems, allowing reduction of model complexity and stiffness. In realistic settings, however, model reduction must contend with uncertainties, which are often greatest in large-scale systems most in need of reduction. Uncertainty is not limited to parameters; one must also address structural uncertainties—e.g., whether a link is present in a network—and the impact of random perturbations, e.g., fluctuating loads or sources. Research under this project developed new methods for the analysis and reduction of complex multiscale networks under uncertainty, by combining computational singular perturbation (CSP) with probabilistic uncertainty quantification. CSP yields asymptotic approximations of reduceddimensionality “slow manifolds” on which a multiscale dynamical system evolves. Introducing

  14. Production cost analysis of Euphorbia lathyris. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Mendel, D.A.

    1979-08-01

    The purpose of this study is to estimate costs of production for Euphorbia lathyris (hereafter referred to as Euphorbia) in commercial-scale quantities. Selection of five US locations for analysis was based on assumed climatic and cultivation requirements. The five areas are: nonirrigated areas (Southeast Kansas and Central Oklahoma, Northeast Louisiana and Central Mississippi, Southern Illinois), and irrigated areas: (San Joaquin Valley and the Imperial Valley, California and Yuma, Arizona). Cost estimates are tailored to reflect each region's requirements and capabilities. Variable costs for inputs such as cultivation, planting, fertilization, pesticide application, and harvesting include material costs, equipment ownership, operating costs, and labor. Fixed costs include land, management, and transportation of the plant material to a conversion facility. Euphorbia crop production costs, on the average, range between $215 per acre in nonirrigated areas to $500 per acre in irrigated areas. Extraction costs for conversion of Euphorbia plant material to oil are estimated at $33.76 per barrel of oil, assuming a plant capacity of 3000 dry ST/D. Estimated Euphorbia crop production costs are competitive with those of corn. Alfalfa production costs per acre are less than those of Euphorbia in the Kansas/Oklahoma and Southern Illinois site, but greater in the irrigated regions. This disparity is accounted for largely by differences in productivity and irrigation requirements.

  15. Photosynthesis energy factory: analysis, synthesis, and demonstration. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1978-11-01

    This quantitative assessment of the potential of a combined dry-land Energy Plantation, wood-fired power plant, and algae wastewater treatment system demonstrates the cost-effectiveness of recycling certain by-products and effluents from one subsystem to another. Designed to produce algae up to the limit of the amount of carbon in municipal wastewater, the algae pond provides a positive cash credit, resulting mainly from the wastewater treatment credit, which may be used to reduce the cost of the Photosynthesis Energy Factory (PEF)-generated electricity. The algae pond also produces fertilizer, which reduces the cost of the biomass produced on the Energy Plantation, and some gas. The cost of electricity was as low as 35 mills per kilowatt-hour for a typical municipally-owned PEF consisting of a 65-MWe power plant, a 144-acre algae pond, and a 33,000-acre Energy Plantation. Using only conventional or near-term technology, the most cost-effective algae pond for a PEF is the carbon-limited secondary treatment system. This system does not recycle CO/sub 2/ from the flue gas. Analysis of the Energy Plantation subsystem at 15 sites revealed that plantations of 24,000 to 36,000 acres produce biomass at the lowest cost per ton. The following sites are recommended for more detailed evaluation as potential demonstration sites: Pensacola, Florida; Jamestown, New York; Knoxville, Tennessee; Martinsville, Virginia, and Greenwood, South Carolina. A major possible extension of the PEF concept is to include the possibility for irrigation.

  16. Rates of progression in diabetic retinopathy during different time periods: a systematic review and meta-analysis

    DEFF Research Database (Denmark)

    Wong, Tien Y; Mwamburi, Mkaya; Klein, Ronald;

    2009-01-01

    This meta-analysis reviews rates of progression of diabetic retinopathy to proliferative diabetic retinopathy (PDR) and/or severe visual loss (SVL) and temporal trends.......This meta-analysis reviews rates of progression of diabetic retinopathy to proliferative diabetic retinopathy (PDR) and/or severe visual loss (SVL) and temporal trends....

  17. Recent Progresses in Analysis of Tongue Manifestation for Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    WEI Bao-guo; CAI Yi-heng; ZHANG Xin-feng; SHEN Lan-sun

    2005-01-01

    Tongue diagnosis is one of the most precious and widely used diagnostic methods in Traditional Chinese Medicine (TCM). However, due to its subjective, qualitative and experience-dependent nature, the studies on tongue characterization have been widely emphasized. This paper surveys recent progresses in analysis of tongue manifestation. These new developments include the cross-network and cross-media color reproduction of tongue image, the automatic segmentation of tongue body based on knowledge, the automatic analysis of curdiness and griminess for the tongue fur and the automatic analysis of plumpness, wryness and dot -thorn of tongue body. The clinic experiments verify the validity of these new methods.

  18. Event-by-event cluster analysis of final states from heavy ion collisions

    OpenAIRE

    Fialkowski, K.; Wit, R.

    1999-01-01

    We present an event-by-event analysis of the cluster structure of final multihadron states resulting from heavy ion collisions. A comparison of experimental data with the states obtained from Monte Carlo generators is shown. The analysis of the first available experimental events suggests that the method is suitable for selecting some different types of events.

  19. Assessing Progress towards Public Health, Human Rights, and International Development Goals Using Frontier Analysis.

    Science.gov (United States)

    Luh, Jeanne; Cronk, Ryan; Bartram, Jamie

    2016-01-01

    Indicators to measure progress towards achieving public health, human rights, and international development targets, such as 100% access to improved drinking water or zero maternal mortality ratio, generally focus on status (i.e., level of attainment or coverage) or trends in status (i.e., rates of change). However, these indicators do not account for different levels of development that countries experience, thus making it difficult to compare progress between countries. We describe a recently developed new use of frontier analysis and apply this method to calculate country performance indices in three areas: maternal mortality ratio, poverty headcount ratio, and primary school completion rate. Frontier analysis is used to identify the maximum achievable rates of change, defined by the historically best-performing countries, as a function of coverage level. Performance indices are calculated by comparing a country's rate of change against the maximum achievable rate at the same coverage level. A country's performance can be positive or negative, corresponding to progression or regression, respectively. The calculated performance indices allow countries to be compared against each other regardless of whether they have only begun to make progress or whether they have almost achieved the target. This paper is the first to use frontier analysis to determine the maximum achievable rates as a function of coverage level and to calculate performance indices for public health, human rights, and international development indicators. The method can be applied to multiple fields and settings, for example health targets such as cessation in smoking or specific vaccine immunizations, and offers both a new approach to analyze existing data and a new data source for consideration when assessing progress achieved. PMID:26812524

  20. Final Progress Report: FRACTURE AND SUBCRITICAL DEBONDING IN THIN LAYERED STRUCTURES: EXPERIMENTS AND MULTI-SCALE MODELING

    Energy Technology Data Exchange (ETDEWEB)

    Reinhold H. Dauskardt

    2005-08-30

    Final technical report detailing unique experimental and multi-scale computational modeling capabilities developed to study fracture and subcritical cracking in thin-film structures. Our program to date at Stanford has studied the mechanisms of fracture and fatigue crack-growth in structural ceramics at high temperature, bulk and thin-film glasses in selected moist environments where we demonstrated the presence of a true mechanical fatigue effect in some glass compositions. We also reported on the effects of complex environments and fatigue loading on subcritical cracking that effects the reliability of MEMS and other micro-devices using novel micro-machined silicon specimens and nanomaterial layers.

  1. The Application of Structured Job Analysis Information Based on the Position Analysis Questionnaire (PAQ). Final Report No. 9.

    Science.gov (United States)

    McCormick, Ernest J.

    The Position Analysis Questionnaire (PAQ) is a job analysis instrument consisting of 187 job elements organized into six divisions. The PAQ was used in the eight studies summarized in this final report. The studies were: (1) ratings of the attribute requirements of PAQ job elements, (2) a series of principal components analyses of these attribute…

  2. An analysis of the practical part of the final apprenticeship examinations at a particular apprenticeship school

    OpenAIRE

    Prknová, Monika

    2014-01-01

    The aim of the thesis entitled "Analysis of the practical part of final examinations in a particular secondary vocational school" is to analyze and evaluate the final field tests 41-53-H/008 Rider and groomer racehorses in 2009 and 2011. In this field of study are educated to perform skilled manual occupations in horse breeding, racing and equestrian sports. In the theoretical part the author deals with the broader circumstances that affect school success of students. There is also ...

  3. Positron tomographic imaging of tumors using monoclonal antibodies. Final progress report, April 15, 1989--October 31, 1995

    International Nuclear Information System (INIS)

    The overall objective of this research is to develop methods for utilizing positron emission tomography (PET) to increase the clinical potential of radiolabeled monoclonal antibodies (MAbs). Enhancement of MAb tumor localization by hyperthermia also was proposed. Studies were to have been performed with both 18F and 124I; however, the lack of its availability (until quite recently) prevented experiments with 124I. Instead, two additional lines of inquiry were initiated in which they utilized aspects of the radiofluorination chemistries originally developed for MAbs for labeling chemotactic peptides and meta-iodobenzylguanidine (MIBG) analogues with 18F. This final report summarizes the original specific aims and the main research accomplishments in studies of mouse, dog and human models

  4. Positron tomographic imaging of tumors using monoclonal antibodies. Final progress report, April 15, 1989--October 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Zalutsky, M.R.

    1997-02-01

    The overall objective of this research is to develop methods for utilizing positron emission tomography (PET) to increase the clinical potential of radiolabeled monoclonal antibodies (MAbs). Enhancement of MAb tumor localization by hyperthermia also was proposed. Studies were to have been performed with both {sup 18}F and {sup 124}I; however, the lack of its availability (until quite recently) prevented experiments with {sup 124}I. Instead, two additional lines of inquiry were initiated in which they utilized aspects of the radiofluorination chemistries originally developed for MAbs for labeling chemotactic peptides and meta-iodobenzylguanidine (MIBG) analogues with {sup 18}F. This final report summarizes the original specific aims and the main research accomplishments in studies of mouse, dog and human models.

  5. Bioconversion of coal derived synthesis gas to liquid fuels. Final quarterly technical progress report, July 1, 1993--September 30, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Jain, M.K.; Worden, R.M.; Grethlein, H.

    1993-10-25

    The overall objective of the project is to develop an integrated two stage fermentation process for conversion of coal-derived synthesis gas to a mixture of alcohols. This is achieved in two steps. In the first step, Butyribacterium methylotrophicum converts carbon monoxide (CO) to butyric and acetic acids. Subsequent fermentation of the acids by Clostridium acetobutylicum leads to the production of butanol and ethanol. The tasks for this quarter were: (1) development/isolation of superior strains for fermentation of syngas, (2) optimization of process conditions for fermentation of syngas, (3) evaluation of bioreactor configuration for improved mass transfer of syngas, (4) development of a membrane-based pervaporation system, (5) optimization of process conditions for reducing carbon and electron loss by H{sub 2}-CO{sub 2} fermentation, and (6) synthesis gas fermentation in single-stage by co-culture. Progress is reported in isolation of CO utilizing anaerobic strains; investigating the product profile for the fermentation of syngas by B. methylotrophicum; and determining the effect of carbon monoxide on growth of C. acetobutylicum.

  6. Purchase of a PhosphorImager System for plant biology research. Final progress report, July 1992--July 1994

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, A.O.

    1993-10-01

    Eight DOE supported plant biologists at the University of California-Berkeley were awarded funds ($163,000) for purchase of a Phosphorlmager System to improve the speed, sensitivity, resolution, and quantitation of radioactive data processing and analysis. These funds were used to purchase a Molecular Dynamics Phosphorlmager System consisting of the phosphorlmager, a densitometer, and high resolution storage phosphor screens that have extremely high trapping and storage capacity for energy emitted from isotopes used for biological research such as {sup 32}P, {sup 14}C, {sup 35}S, and {sup 125}I. Software provided with the package permits analysis of the data in several unique ways that are not currently feasible With other methods for analysis. The University of California has purchased additional computer hardware (A MacIntosh Quadra 800 Computer) and has upgraded an IBM computer Mod6l PS2-486 linked with on-line and on off-line workstations via ethernet systems for analysis of data. Data files can also be converted to a TIFF format suitable for graphic analysis and image production on the MacIntosh computer. The system is providing unique advantages for quantitation of data over extremely wide ranges of isotope levels and provides the ability to analyze and manipulate data over wide ranges of sensitivity not previously available with previously used methods of isotope quantitation.

  7. Progress in the RAMI analysis of a conceptual LHCD system for DEMO

    Science.gov (United States)

    Mirizzi, F.

    2014-02-01

    Reliability, Availability, Maintainability and Inspectability (RAMI) concepts and techniques, that acquired great importance during the first manned space missions, have been progressively extended to industrial, scientific and consumer equipments to assure them satisfactory performances and lifetimes. In the design of experimental facilities, like tokamaks, mainly aimed at demonstrating validity and feasibility of scientific theories, RAMI analysis has been often left aside. DEMO, the future prototype fusion reactors, will be instead designed for steadily delivering electrical energy to commercial grids, so that the RAMI aspects will assume an absolute relevance since their initial design phases. A preliminary RAMI analysis of the LHCD system for the conceptual EU DEMO reactor is given in the paper.

  8. Recent progress of surface analysis (AES, XPS, and TOF-SIMS) and their application to corrosion analysis

    International Nuclear Information System (INIS)

    Auger Electron Spectroscopy (AES), X-ray Photoelectron Spectroscopy (XPS), and Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) are surface analysis techniques which provide atomic- and molecular-level surface chemical information. They are widely used for failure analysis, quality control, and research and development of advanced materials and devices. In this review, we overview the recent progress of the commercial apparatus, and also highlight their improved sensitivity and depth profiling capabilities. We also introduce their recent application in corrosion science. (author)

  9. Hybrid solar thermal-photovoltaic systems demonstration, Phase I and II. Final technical progress report, July 5, 1979-December 1982

    Energy Technology Data Exchange (ETDEWEB)

    Loferski, J.J. (ed.)

    1983-12-01

    The purpose of the project is to investigate a system based on combined photovoltaic/thermal (PV/T) panels to supply the energy needs of a small single family residence. The system finally selected and constructed uses PV/T panels which utilize air as the heat transfer medium. Optimization of thermal performance was accomplished by attaching metal fins to the back surface of each cell which significantly increased the heat transfer coefficient from the solar cells to the air stream. The other major components of the selected system are an air-to-air heat pump, a rock bin thermal energy storage bin, a synchronous dc-to-ac converter, a microprocessor to control the system, a heat exchanger for the domestic hot water system and of course the building itself which is a one story, well insulated structure having a floor area of 1200 ft/sup 2/. A prototype collector was constructed and tested. Based on this experience, twenty collectors, containing 2860 four inch diameter solar cells, were constructed and installed on the building. Performance of the system was simulated using a TRNSYS-derived program, modified to accommodate PV/T panels and to include the particular components included in the selected system. Simulation of the performance showed that about 65 percent of the total annual energy needs of the building would be provided by the PV/T system. Of this total, about one half is produced at a time when it can be used in the building and one half must be sold back to the utility.

  10. Pion-nucleon partial wave analysis and study of baryon structure. Progress report, June 1, 1979-May 31, 1981

    International Nuclear Information System (INIS)

    This report details progress toward completion of a long-term pion-nucleon partial wave analysis, summarizing results and conclusions to date. The report also discussed progress in using partial wave and resonance parameter results to test dynamical models of the baryon and in better understanding interquark forces within baryons

  11. Progressive failure analysis of slope with strain-softening behaviour based on strength reduction method

    Institute of Scientific and Technical Information of China (English)

    Ke ZHANG; Ping CAO; Rui BAO

    2013-01-01

    Based on the strength reduction method and strain-softening model,a method for progressive failure analysis of strain-softening slopes was presented in this paper.The mutation is more pronounced in strain-softening analysis,and the mutation of displacement at slope crest was taken as critical failure criterion.An engineering example was provided to demonstrate the validity of the present method.This method was applied to a cut slope in an industry site.The results are as follows: (1) The factor of safety and the critical slip surface obtained by the present method are between those by peak and residual strength.The analysis with peak strength would lead to non-conservative results,but that with residual strength tends to be overly conservative.(2) The thickness of the shear zone considering strain-softening behaviour is narrower than that with non-softening analysis.(3) The failure of slope is the process of the initiation,propagation and connection of potential failure surface.The strength parameters are mobilized to a non-uniform degree while progressive failure occurs in the slope.(4) The factor of safety increases with the increase of residual shear strain threshold and elastic modulus.The failure mode of slope changes from shallow slip to deep slip.Poisson's ratio and dilation angle have little effect on the results.

  12. LDRD final report : robust analysis of large-scale combinatorial applications.

    Energy Technology Data Exchange (ETDEWEB)

    Carr, Robert D.; Morrison, Todd (University of Colorado, Denver, CO); Hart, William Eugene; Benavides, Nicolas L. (Santa Clara University, Santa Clara, CA); Greenberg, Harvey J. (University of Colorado, Denver, CO); Watson, Jean-Paul; Phillips, Cynthia Ann

    2007-09-01

    Discrete models of large, complex systems like national infrastructures and complex logistics frameworks naturally incorporate many modeling uncertainties. Consequently, there is a clear need for optimization techniques that can robustly account for risks associated with modeling uncertainties. This report summarizes the progress of the Late-Start LDRD 'Robust Analysis of Largescale Combinatorial Applications'. This project developed new heuristics for solving robust optimization models, and developed new robust optimization models for describing uncertainty scenarios.

  13. TA-55 Final Safety Analysis Report Comparison Document and DOE Safety Evaluation Report Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Alan Bond

    2001-04-01

    This document provides an overview of changes to the currently approved TA-55 Final Safety Analysis Report (FSAR) that are included in the upgraded FSAR. The DOE Safety Evaluation Report (SER) requirements that are incorporated into the upgraded FSAR are briefly discussed to provide the starting point in the FSAR with respect to the SER requirements.

  14. Spent nuclear fuel project - criteria document spent nuclear fuel final safety analysis report

    International Nuclear Information System (INIS)

    The criteria document provides the criteria and planning guidance for developing the Spent Nuclear Fuel (SNF) Final Safety Analysis Report (FSAR). This FSAR will support the US Department of Energy, Richland Operations Office decision to authorize the procurement, installation, installation acceptance testing, startup, and operation of the SNF Project facilities (K Basins, Cold Vacuum Drying Facility, and Canister Storage Building)

  15. Participation in the US Department of Energy reactor sharing program. Final progress report, October 1996--September 1997

    Energy Technology Data Exchange (ETDEWEB)

    Mulder, R.U.; Benneche, P.E.; Hosticka, B.

    1998-04-01

    The objective of the DOE supported Reactor Sharing Program is to increase the availability of university nuclear reactor facilities to non-reactor-owning educational institutions. The educational and research programs of these user institutions is enhanced by the use of the nuclear facilities. Several methods have been used by the UVA Reactor Facility to achieve this objective. First, many college and secondary school groups toured the Reactor Facility and viewed the UVAR reactor and associated experimental facilities. Second, advanced undergraduate and graduate classes from area colleges and universities visited the facility to perform experiments in nuclear engineering and physics which would not be possible at the user institution. Third, irradiation and analysis services at the Facility have been made available for research by faculty and students from user institutions. Fourth, some institutions have received activated material from UVA from use at their institutions. These areas are discussed in this report.

  16. Progressive Collapse Analysis of Steel Framed Structures with I-Beams and Truss Beams using Linear Static Procedure

    OpenAIRE

    Fadaei, Sepideh

    2012-01-01

    ABSTRACT: Progressive collapse starts with a local damage or loss of some members of the structure leading to failure at large parts of a structure. Due to the recent disastrous events like world Trade Center in USA, taking measures in reducing the potential of progressive collapse (PC) of structures during the analysis and design stages is becoming a necessity for the structures. A number of computational analysis programs, such as ETABS, SAP2000, ABAQUS can be used to simulate the structure...

  17. Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium: a system-level analysis.

    Directory of Open Access Journals (Sweden)

    Jeffrey M Skerker

    2005-10-01

    Full Text Available Two-component signal transduction systems, comprised of histidine kinases and their response regulator substrates, are the predominant means by which bacteria sense and respond to extracellular signals. These systems allow cells to adapt to prevailing conditions by modifying cellular physiology, including initiating programs of gene expression, catalyzing reactions, or modifying protein-protein interactions. These signaling pathways have also been demonstrated to play a role in coordinating bacterial cell cycle progression and development. Here we report a system-level investigation of two-component pathways in the model organism Caulobacter crescentus. First, by a comprehensive deletion analysis we show that at least 39 of the 106 two-component genes are required for cell cycle progression, growth, or morphogenesis. These include nine genes essential for growth or viability of the organism. We then use a systematic biochemical approach, called phosphotransfer profiling, to map the connectivity of histidine kinases and response regulators. Combining these genetic and biochemical approaches, we identify a new, highly conserved essential signaling pathway from the histidine kinase CenK to the response regulator CenR, which plays a critical role in controlling cell envelope biogenesis and structure. Depletion of either cenK or cenR leads to an unusual, severe blebbing of cell envelope material, whereas constitutive activation of the pathway compromises cell envelope integrity, resulting in cell lysis and death. We propose that the CenK-CenR pathway may be a suitable target for new antibiotic development, given previous successes in targeting the bacterial cell wall. Finally, the ability of our in vitro phosphotransfer profiling method to identify signaling pathways that operate in vivo takes advantage of an observation that histidine kinases are endowed with a global kinetic preference for their cognate response regulators. We propose that this

  18. Comparison of various procedures for progressive collapse analysis of cable-stayed bridges

    Institute of Scientific and Technical Information of China (English)

    Jian-guo CAI; Yi-xiang XU; Li-ping ZHUANG; Jian FENG; Jin ZHANG

    2012-01-01

    Alternate path (AP) method is the most widely used method for the progressive collapse analysis,and its application in frame structures has been well proved.However,the application of AP method for other structures,especially for cable-stayed structures,should be further developed.The four analytical procedures,i.e.,linear static,nonlinear static,linear dynamic,and nonlinear dynamic were firstly improved by taking into account the initial state.Then a cable-stayed structure was studied using the four improved methods.Furthermore,the losses of both one cable and two cables were discussed.The results show that for static and dynamic analyses of the cable-stayed bridges,there is large difference between the results obtained from simulations starting with either a deformed or a nondeformed configuration at the time of cable loss.The static results are conservative in the vicinity of the ruptured cable,but the dynamic effect of the cable loss in the area farther away from the loss-cable cannot be considered.Moreover,the dynamic amplification factor of 2.0 is found to be a good estimate for static analysis procedures,since linear static and linear dynamic procedures yield approximately the same maximum vertical deflection.The results of the comprehensive evaluation of the cable failure show that the tread of the progressive failure of the cable-stayed bridges decreases when the location of the failed cables is closer to the pylon.

  19. High beta and second region stability analysis and ICRF edge modeling: Progress report

    International Nuclear Information System (INIS)

    This report describes the tasks accomplished under Department of Energy contract No. FG02-86ER53236 in modeling the edge plasma- antenna interaction that occurs during Ion Cyclotron Range of Frequency (ICRF) heating. This work has resulted in the development of several codes which determine kinetic and fluid modifications to the edge plasma. When used in combination, these codes predict the level of impurity generation observed in experiments on the Princeton Large Torus. In addition, these models suggest improvements to the design of ICRF antennas. Also described is progress made on high beta and second region analysis. Code development for a comprehensive infernal mode analysis code is nearing completion. A method has been developed for parameterizing the second region of stability and is applied to circular cross section tokamaks. Various studies for high beta experimental devices such as PBX-M and DIII-D have been carried out and are reported on. 19 refs., 8 figs., 1 tab

  20. A Framework for Performing Multiscale Stochastic Progressive Failure Analysis of Composite Structures

    Science.gov (United States)

    Bednarcyk, Brett A.; Arnold, Steven M.

    2007-01-01

    A framework is presented that enables coupled multiscale analysis of composite structures. The recently developed, free, Finite Element Analysis-Micromechanics Analysis Code (FEAMAC) software couples the Micromechanics Analysis Code with Generalized Method of Cells (MAC/GMC) with ABAQUS to perform micromechanics based FEA such that the nonlinear composite material response at each integration point is modeled at each increment by MAC/GMC. As a result, the stochastic nature of fiber breakage in composites can be simulated through incorporation of an appropriate damage and failure model that operates within MAC/GMC on the level of the fiber. Results are presented for the progressive failure analysis of a titanium matrix composite tensile specimen that illustrate the power and utility of the framework and address the techniques needed to model the statistical nature of the problem properly. In particular, it is shown that incorporating fiber strength randomness on multiple scales improves the quality of the simulation by enabling failure at locations other than those associated with structural level stress risers.

  1. Recent Research Progress in Fault Analysis of Complex Electric Power Systems

    Directory of Open Access Journals (Sweden)

    WANG, Z.

    2010-02-01

    Full Text Available In this paper, we adopt a novel approach to the fault analysis of complex electric power systems. Electric power system is one of the most complex artificial systems in the world. Its safe, steady, economical and reliable operating plays a very important part in guaranteeing socioeconomic development, and even in safeguarding social stability. The complexity of electric power system is determined by its characteristics about constitution, configuration, operation, organization, etc. No matter if, we adopt new analytical methods or technical means, we must have a distinct recognition of electric power system itself and its complexity, and increase analysis continuously, operation and control level. In this paper, utilizing real-time measurements of phasor measurement unit, based on graph theory and multivariate statistical analysis theory, we are using mainly Breadth-first search, Depth-first search and cluster analysis. Then, we seek for the uniform laws of marked changes of electrical quantities. Then we can carry out fast and exact analysis of fault component. Finally, we can accomplish fault isolation. According to line fault and bus-bar fault (single-phase fault, phase-to-phase fault and three-phase fault in complex electric power systems, we have carried out a great deal of simulation experiments and obtained ideal results. These researches have proven that the faults in complex electric power systems can be explored successfully by analysis and calculation based on graph theory and multivariate statistical analysis theory.

  2. Organometallic Chemistry. Final Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2003-07-14

    The Gordon Research Conference (GRC) on Organometallic Chemistry was held at Salve Regina, Newport, Rhode Island, 7/21-26/02. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

  3. The Analysis of Surrounding Structure Effect on the Core Degradation Progress with COMPASS Code

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Jun Ho; Son, Dong Gun; Kim, Jong Tae; Park, Rae Jun; Kim, Dong Ha [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    In line with the importance of severe accident analysis after Fukushima accident, the development of integrated severe accident code has been launched by the collaboration of three institutes in Korea. KAERI is responsible to develop modules related to the in-vessel phenomena, while other institutes are to the containment and severe accident mitigation facility, respectively. In the first phase, the individual severe accident module has been developed and the construction of integrated analysis code is planned to perform in the second phase. The basic strategy is to extend the design basis analysis codes of SPACE and CAP, which are being validated in Korea for the severe accident analysis. In the first phase, KAERI has targeted to develop the framework of severe accident code, COMPASS (COre Meltdown Progression Accident Simulation Software), covering the severe accident progression in a vessel from a core heat-up to a vessel failure as a stand-alone fashion. In order to analyze the effect of surrounding structure, the melt progression has been compared between the central zone and the most outer zone under the condition of constant radial power peaking factor. Figure 2 and 3 shows the fuel element temperature and the clad mass at the central zone, respectively. Due to the axial power peaking factor, the axial node No.3 has the highest temperature, while the top and bottom nodes have the lowest temperature. When the clad temperature reaches to the Zr melting temperature (2129.15K), the Zr starts to melt. The axial node No.2 reaches to the fuel melting temperature about 5000 sec and the molten fuel relocates to the node No.1, which results to the blockage of flow area in node No.1. The blocked flow area becomes to open about 6100 sec due to the molten ZrO{sub 2} mass relocation to core support plate. Figure 4 and 5 shows the fuel element temperature and the clad mass at the most outer zone, respectively. It is shown that the fuel temperature increase more slowly

  4. Final safety and hazards analysis for the Battelle LOCA simulation tests in the NRU reactor

    International Nuclear Information System (INIS)

    This is the final safety and hazards report for the proposed Battelle LOCA simulation tests in NRU. A brief description of equipment test design and operating procedure precedes a safety analysis and hazards review of the project. The hazards review addresses potential equipment failures as well as potential for a metal/water reaction and evaluates the consequences. The operation of the tests as proposed does not present an unacceptable risk to the NRU Reactor, CRNL personnel or members of the public. (author)

  5. Analysis of Final Energy Demand by Sector in Malaysia using MAED Model

    International Nuclear Information System (INIS)

    Energy supply security is important in ensuring a long term supply to fulfill the growing energy demand. This paper presents the use of IAEA energy planning tool, Model for Analysis of Energy Demand (MAED) to analyze, simulate and compare final energy demand by five different sectors in Malaysia under some assumptions, bounds and restrictions and the outcome can be used for planning of energy supply in future. (author)

  6. Visual and statistical analysis of {sup 18}F-FDG PET in primary progressive aphasia

    Energy Technology Data Exchange (ETDEWEB)

    Matias-Guiu, Jordi A.; Moreno-Ramos, Teresa; Garcia-Ramos, Rocio; Fernandez-Matarrubia, Marta; Oreja-Guevara, Celia; Matias-Guiu, Jorge [Hospital Clinico San Carlos, Department of Neurology, Madrid (Spain); Cabrera-Martin, Maria Nieves; Perez-Castejon, Maria Jesus; Rodriguez-Rey, Cristina; Ortega-Candil, Aida; Carreras, Jose Luis [San Carlos Health Research Institute (IdISSC) Complutense University of Madrid, Department of Nuclear Medicine, Hospital Clinico San Carlos, Madrid (Spain)

    2015-05-01

    Diagnosing progressive primary aphasia (PPA) and its variants is of great clinical importance, and fluorodeoxyglucose (FDG) positron emission tomography (PET) may be a useful diagnostic technique. The purpose of this study was to evaluate interobserver variability in the interpretation of FDG PET images in PPA as well as the diagnostic sensitivity and specificity of the technique. We also aimed to compare visual and statistical analyses of these images. There were 10 raters who analysed 44 FDG PET scans from 33 PPA patients and 11 controls. Five raters analysed the images visually, while the other five used maps created using Statistical Parametric Mapping software. Two spatial normalization procedures were performed: global mean normalization and cerebellar normalization. Clinical diagnosis was considered the gold standard. Inter-rater concordance was moderate for visual analysis (Fleiss' kappa 0.568) and substantial for statistical analysis (kappa 0.756-0.881). Agreement was good for all three variants of PPA except for the nonfluent/agrammatic variant studied with visual analysis. The sensitivity and specificity of each rater's diagnosis of PPA was high, averaging 87.8 and 89.9 % for visual analysis and 96.9 and 90.9 % for statistical analysis using global mean normalization, respectively. In cerebellar normalization, sensitivity was 88.9 % and specificity 100 %. FDG PET demonstrated high diagnostic accuracy for the diagnosis of PPA and its variants. Inter-rater concordance was higher for statistical analysis, especially for the nonfluent/agrammatic variant. These data support the use of FDG PET to evaluate patients with PPA and show that statistical analysis methods are particularly useful for identifying the nonfluent/agrammatic variant of PPA. (orig.)

  7. Recent progress of J-PARC MLF data analysis environment: instrument status data and remote access

    International Nuclear Information System (INIS)

    We report the recent progress on two fields of data analysis environment of J-PARC (Japan Proton Accelerator Research Complex) MLF (Materials and Life Science Experimental Facility). One is a utilization of event data of instrument status, another is a development of remote data access. Event data of instrument status TrigNET, which is a universal signal readout module developed in KEK, can acquire various instrument status, such as a tensile load or a goniometer position, as time-tagged event data in the same manner with a neutron detection signal. It allows us to treat both events of neutron detection and instrument status on an identical time-line. In the other words, instrument status can be handled at same time precision as the neutron detection event. In order to implement this function, our data analysis software has been upgraded. For example, this upgrade made flexible to analyze data under cyclic load-unload deformation or continuous sample rotation. Remote data access The remote data access is an key service for a large user facility such as J-PARC MLF. Developments of two components for the remote data access are on-going. The MLF experimental database system will provide users a search and a download for raw data and meta-data of their experiments through a web browser. The remote data analysis service will provide data analysis environment on a web browser utilizing computing resource at MLF.

  8. Does colon cancer ever metastasize to bone first? a temporal analysis of colorectal cancer progression

    International Nuclear Information System (INIS)

    It is well recognized that colorectal cancer does not frequently metastasize to bone. The aim of this retrospective study was to establish whether colorectal cancer ever bypasses other organs and metastasizes directly to bone and whether the presence of lung lesions is superior to liver as a better predictor of the likelihood and timing of bone metastasis. We performed a retrospective analysis on patients with a clinical diagnosis of colon cancer referred for staging using whole-body 18F-FDG PET and CT or PET/CT. We combined PET and CT reports from 252 individuals with information concerning patient history, other imaging modalities, and treatments to analyze disease progression. No patient had isolated osseous metastasis at the time of diagnosis, and none developed isolated bone metastasis without other organ involvement during our survey period. It took significantly longer for colorectal cancer patients to develop metastasis to the lungs (23.3 months) or to bone (21.2 months) than to the liver (9.8 months). Conclusion: Metastasis only to bone without other organ involvement in colorectal cancer patients is extremely rare, perhaps more rare than we previously thought. Our findings suggest that resistant metastasis to the lungs predicts potential disease progression to bone in the colorectal cancer population better than liver metastasis does

  9. Rate Dependent Multicontinuum Progressive Failure Analysis of Woven Fabric Composite Structures under Dynamic Impact

    Directory of Open Access Journals (Sweden)

    James Lua

    2004-01-01

    Full Text Available Marine composite materials typically exhibit significant rate dependent response characteristics when subjected to extreme dynamic loading conditions. In this work, a strain-rate dependent continuum damage model is incorporated with multicontinuum technology (MCT to predict damage and failure progression for composite material structures. MCT treats the constituents of a woven fabric composite as separate but linked continua, thereby allowing a designer to extract constituent stress/strain information in a structural analysis. The MCT algorithm and material damage model are numerically implemented with the explicit finite element code LS-DYNA3D via a user-defined material model (umat. The effects of the strain-rate hardening model are demonstrated through both simple single element analyses for woven fabric composites and also structural level impact simulations of a composite panel subjected to various impact conditions. Progressive damage at the constituent level is monitored throughout the loading. The results qualitatively illustrate the value of rate dependent material models for marine composite materials under extreme dynamic loading conditions.

  10. Does colon cancer ever metastasize to bone first? a temporal analysis of colorectal cancer progression

    Directory of Open Access Journals (Sweden)

    Gayed Isis W

    2009-08-01

    Full Text Available Abstract Background It is well recognized that colorectal cancer does not frequently metastasize to bone. The aim of this retrospective study was to establish whether colorectal cancer ever bypasses other organs and metastasizes directly to bone and whether the presence of lung lesions is superior to liver as a better predictor of the likelihood and timing of bone metastasis. Methods We performed a retrospective analysis on patients with a clinical diagnosis of colon cancer referred for staging using whole-body 18F-FDG PET and CT or PET/CT. We combined PET and CT reports from 252 individuals with information concerning patient history, other imaging modalities, and treatments to analyze disease progression. Results No patient had isolated osseous metastasis at the time of diagnosis, and none developed isolated bone metastasis without other organ involvement during our survey period. It took significantly longer for colorectal cancer patients to develop metastasis to the lungs (23.3 months or to bone (21.2 months than to the liver (9.8 months. Conclusion: Metastasis only to bone without other organ involvement in colorectal cancer patients is extremely rare, perhaps more rare than we previously thought. Our findings suggest that resistant metastasis to the lungs predicts potential disease progression to bone in the colorectal cancer population better than liver metastasis does.

  11. Network analysis of breast cancer progression and reversal using a tree-evolving network algorithm.

    Directory of Open Access Journals (Sweden)

    Ankur P Parikh

    2014-07-01

    Full Text Available The HMT3522 progression series of human breast cells have been used to discover how tissue architecture, microenvironment and signaling molecules affect breast cell growth and behaviors. However, much remains to be elucidated about malignant and phenotypic reversion behaviors of the HMT3522-T4-2 cells of this series. We employed a "pan-cell-state" strategy, and analyzed jointly microarray profiles obtained from different state-specific cell populations from this progression and reversion model of the breast cells using a tree-lineage multi-network inference algorithm, Treegl. We found that different breast cell states contain distinct gene networks. The network specific to non-malignant HMT3522-S1 cells is dominated by genes involved in normal processes, whereas the T4-2-specific network is enriched with cancer-related genes. The networks specific to various conditions of the reverted T4-2 cells are enriched with pathways suggestive of compensatory effects, consistent with clinical data showing patient resistance to anticancer drugs. We validated the findings using an external dataset, and showed that aberrant expression values of certain hubs in the identified networks are associated with poor clinical outcomes. Thus, analysis of various reversion conditions (including non-reverted of HMT3522 cells using Treegl can be a good model system to study drug effects on breast cancer.

  12. Damage analysis and fundamental studies. Quarterly progress report, January--March 1979

    Energy Technology Data Exchange (ETDEWEB)

    Zwilsky, Klaus M.

    1979-05-01

    This report is the fifth in a series of Quarterly Technical Progress Reports on Damage Analysis and Fundamental Studies (DAFS) which is one element of the Fusion Reactor Materials Program, conducted in support of the Magnetic Fusion Energy Program. This report is organized along topical lines in parallel to a Program Plan of the same title (to be published) so that activities and accomplishments may be followed readily relative to that Program Plan. Thus, the work of a given laboratory may appear throughout the report. Chapters 1 and 2 report topics which are generic to all of the DAFS Program: DAFS Task Group Activities and Irradiation Test Facilities, respectively. Chapters 3, 4, and 5 report the work that is specific to each of the subtasks around which the program is structured: A) Environmental Characterization, B) Damage Production, and C) Damage Microstructure Evolution and Mechanical Behavior.

  13. Cohesive Laws and Progressive Damage Analysis of Composite Bonded Joints, a Combined Numerical/Experimental Approach

    Science.gov (United States)

    Girolamo, Donato; Davila, Carlos G.; Leone, Frank A.; Lin, Shih-Yung

    2015-01-01

    The results of an experimental/numerical campaign aimed to develop progressive damage analysis (PDA) tools for predicting the strength of a composite bonded joint under tensile loads are presented. The PDA is based on continuum damage mechanics (CDM) to account for intralaminar damage, and cohesive laws to account for interlaminar and adhesive damage. The adhesive response is characterized using standard fracture specimens and digital image correlation (DIC). The displacement fields measured by DIC are used to calculate the J-integrals, from which the associated cohesive laws of the structural adhesive can be derived. A finite element model of a sandwich conventional splice joint (CSJ) under tensile loads was developed. The simulations, in agreement with experimental tests, indicate that the model is capable of predicting the interactions of damage modes that lead to the failure of the joint.

  14. Micromechanics-Based Progressive Failure Analysis of Composite Laminates Using Different Constituent Failure Theories

    Science.gov (United States)

    Moncada, Albert M.; Chattopadhyay, Aditi; Bednarcyk, Brett A.; Arnold, Steven M.

    2008-01-01

    Predicting failure in a composite can be done with ply level mechanisms and/or micro level mechanisms. This paper uses the Generalized Method of Cells and High-Fidelity Generalized Method of Cells micromechanics theories, coupled with classical lamination theory, as implemented within NASA's Micromechanics Analysis Code with Generalized Method of Cells. The code is able to implement different failure theories on the level of both the fiber and the matrix constituents within a laminate. A comparison is made among maximum stress, maximum strain, Tsai-Hill, and Tsai-Wu failure theories. To verify the failure theories the Worldwide Failure Exercise (WWFE) experiments have been used. The WWFE is a comprehensive study that covers a wide range of polymer matrix composite laminates. The numerical results indicate good correlation with the experimental results for most of the composite layups, but also point to the need for more accurate resin damage progression models.

  15. ANSI/ASHRAE/IESNA Standard 90.1-2007 Final Determination Quantitative Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, Mark A.; Liu, Bing; Richman, Eric E.; Winiarski, David W.

    2011-05-01

    The United States (U.S.) Department of Energy (DOE) conducted a final quantitative analysis to assess whether buildings constructed according to the requirements of the American National Standards Institute (ANSI)/American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1-2007 would result in energy savings compared with buildings constructed to ANSI/ASHRAE/IESNA Standard 90.1-2004. The final analysis considered each of the 44 addenda to ANSI/ASHRAE/IESNA Standard 90.1-2004 that were included in ANSI/ASHRAE/IESNA Standard 90.1-2007. All 44 addenda processed by ASHRAE in the creation of Standard 90.1-2007 from Standard 90.1-2004 were reviewed by DOE, and their combined impact on a suite of 15 building prototype models in 15 ASHRAE climate zones was considered. Most addenda were deemed to have little quantifiable impact on building efficiency for the purpose of DOE’s final determination. However, out of the 44 addenda, 9 were preliminarily determined to have measureable and quantifiable impact.

  16. Targeted serum metabolite profiling and sequential metabolite ratio analysis for colorectal cancer progression monitoring.

    Science.gov (United States)

    Zhu, Jiangjiang; Djukovic, Danijel; Deng, Lingli; Gu, Haiwei; Himmati, Farhan; Abu Zaid, Mohammad; Chiorean, Elena Gabriela; Raftery, Daniel

    2015-10-01

    Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and a major cause of human morbidity and mortality. In addition to early detection, close monitoring of disease progression in CRC can be critical for patient prognosis and treatment decisions. Efforts have been made to develop new methods for improved early detection and patient monitoring; however, research focused on CRC surveillance for treatment response and disease recurrence using metabolomics has yet to be reported. In this proof of concept study, we applied a targeted liquid chromatography tandem mass spectrometry (LC-MS/MS) metabolic profiling approach focused on sequential metabolite ratio analysis of serial serum samples to monitor disease progression from 20 CRC patients. The use of serial samples reduces patient to patient metabolic variability. A partial least squares-discriminant analysis (PLS-DA) model using a panel of five metabolites (succinate, N2, N2-dimethylguanosine, adenine, citraconic acid, and 1-methylguanosine) was established, and excellent model performance (sensitivity = 0.83, specificity = 0.94, area under the receiver operator characteristic curve (AUROC) = 0.91 was obtained, which is superior to the traditional CRC monitoring marker carcinoembryonic antigen (sensitivity = 0.75, specificity = 0.76, AUROC = 0.80). Monte Carlo cross validation was applied, and the robustness of our model was clearly observed by the separation of true classification models from the random permutation models. Our results suggest the potential utility of metabolic profiling for CRC disease monitoring. PMID:26342311

  17. Analysis on Thematic Structure and Thematic Progression in Obama's weekly radio speech

    Institute of Scientific and Technical Information of China (English)

    李成烨

    2016-01-01

    Thematic structure and thematic progression are important concept of textual function. Based on the example of Obama's weekly radio speech, we can examine the practicality of thematic structure and thematic progression and give a guidance for preparation of political speeches.

  18. A phenomenological analysis of melt progression in the lower head of a pressurized water reactor

    International Nuclear Information System (INIS)

    Highlights: • We propose a phenomenological description of melt progression into the lower head. • We examine changes in heat loads on the vessel. • Heat loads are more severe than emphasized by the bounding situation assumption. • Both primary circuit and ex-vessel reflooding are necessary for in-vessel retention. • Vessel failure conditions are examined. - Abstract: The analysis of in-vessel corium cooling (IVC) and retention (IVR) involves the description of very complex and transient physical phenomena. To get round this difficulty, “bounding” situations are often emphasized for the demonstration of corium coolability, by vessel flooding and/or by reactor pit flooding. This approach however comes up against its own limitations. More realistic melt progression scenarios are required to provide plausible corium configurations and vessel failure conditions. Work to develop more realistic melt progression scenarios has been done at CEA, in collaboration with EDF. Development has concentrated on the French 1300 MWe PWR, considering both dry scenarios and the possibility of flooding of the RPC (reactor primary circuit) and/or the reactor pit. The models used for this approach have been derived from the analysis of the TMI2 accident and take benefit from the lessons derived from several programs related to pool thermal hydraulics (BALI, COPO, ACOPO, etc.), material interactions (RASPLAV, MASCA), critical heat flux (CHF) on the external surface of the vessel (KAIST, SULTAN, ULPU), etc. Important conclusions of this work are as follows: (a)After the start of corium melting and onset of melt formation in the core at low pressure (∼1 to 5 bars), it seems questionable that RPV (reactor pressure vessel) reflooding alone would be sufficient to achieve corium retention in the vessel; (b)If the vessel is not cooled externally, it may fail due to local heat-up before the whole core fuel inventory is relocated in the lower head; (c)Even if the vessel is

  19. Progress in the neutronic core conversion (HEU-LEU) analysis of Ghana research reactor-1.

    Energy Technology Data Exchange (ETDEWEB)

    Anim-Sampong, S.; Maakuu, B. T.; Akaho, E. H. K.; Andam, A.; Liaw, J. J. R.; Matos, J. E.; Nuclear Engineering Division; Ghana Atomic Energy Commission; Kwame Nkrumah Univ. of Science and Technology

    2006-01-01

    The Ghana Research Reactor-1 (GHARR-1) is a commercial version of the Miniature Neutron Source Reactor (MNSR) and has operated at different power levels since its commissioning in March 1995. As required for all nuclear reactors, neutronic and thermal hydraulic analysis are being performed for the HEU-LEU core conversion studies of the Ghana Research Reactor-1 (GHARR-1) facility, which is a commercial version of the Miniature Neutron Source Reactor (MNSR). Stochastic Monte Carlo particle transport methods and tools (MCNP4c/MCNP5) were used to fine-tune a previously developed 3-D MCNP model of the GHARR-1 facility and perform neutronic analysis of the 90.2% HEU reference and candidate LEU (UO{sub 2}, U{sub 3}Si{sub 2}, U-9Mo) fresh cores with varying enrichments from 12.6%-19.75%. In this paper, the results of the progress made in the Monte Carlo neutronic analysis of the HEU reference and candidate LEU fuels are presented. In particular, a comparative performance assessment of the LEU with respect to neutron flux variations in the fission chamber and experimental irradiation channels are highlighted.

  20. Rapid analysis of hay attributes using NIRS. Final report, Task II alfalfa supply system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-24

    This final report provides technical information on the development of a near infrared reflectance spectroscopy (NIRS) system for the analysis of alfalfa hay. The purpose of the system is to provide consistent quality for processing alfalfa stems for fuel and alfalfa leaf meal products for livestock feed. Project tasks were to: (1) develop an NIRS driven analytical system for analysis of alfalfa hay and processed alfalfa products; (2) assist in hiring a qualified NIRS technician and recommend changes in testing equipment necessary to provide accurate analysis; (3) calibrate the NIRS instrument for accurate analyses; and (4) develop prototype equipment and sampling procedures as a first step towards development of a totally automated sampling system that would rapidly sample and record incoming feedstock and outbound product. An accurate hay testing program was developed, along with calibration equations for analyzing alfalfa hay and sun-cured alfalfa pellets. A preliminary leaf steam calibration protocol was also developed. 7 refs., 11 figs., 10 tabs.

  1. WEXA: exergy analysis for increasing the efficiency of air/water heat pumps - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Gasser, L.; Wellig, B.; Hilfiker, K.

    2008-04-15

    This comprehensive final report for the Swiss Federal Office of Energy (SFOE) presents the results of a study at the made by the Engineering and Architecture department at the Lucerne University of Applied Sciences and Arts. The subject of the WEXA study (Waermepumpen-Exergie-Analyse - heat pump exergy analysis) is the analysis of the operation of air/water heat-pumps using exergy analysis methods. The basic thermodynamics of heating systems using heat-pumps is discussed. The exergy analyses and exergy balances for the various components and processes of an air/water heat-pump are presented and discussed. Comparisons are presented for heat-pumps with on/off and continuous control systems for their compressors and fans. The paper is concluded with a collection of appendices on the subject.

  2. A final report on stress analysis of seal disc of 500 MWe PHWR

    International Nuclear Information System (INIS)

    In Pressurised Heavy Water Reactor (PHWR) on-power refuelling is done by use of fuelling machine. Before refuelling, sealing plug assembly is removed from the end-fitting of the coolant channel and after refuelling the sealing plug is reinstalled back in to the end-fitting. The seal disc is a part of sealing plug assembly. Its function is to create sealing action for the heavy water inside the coolant channel. A systematic developmental work is done to arrive at a final configuration of the seal disc. This is done to minimise the stresses in the body of the seal disc and at the same time to obtain required seating reaction to avoid heavy water leakage. It is observed that stresses computed for the final configuration by linear elastic analysis are more than the allowable value as per ASME Section III, Division 1. This calls for elasto-plastic analysis to find out collapse load to satisfy ASME codal limits as per special provision of NB-3228.1 (1986). The elasto-plastic analysis showed that the seal disc meets ASME codal limits for all stages of loading. (author). 8 refs., 2 tabs., 7 figs

  3. Report bio-diesel analysis: Environmental analysis and the economy of the sector: Final report

    International Nuclear Information System (INIS)

    The results of a study on the environmental and economical aspects of the production of bio-diesel (rapeseed methylester or RME) are presented. Previous studies, carried out elsewhere, are limited to only a few environmental aspects, do not take into account all the input and output flows, or do not calculate environmental interventions regarding all the products that occur in the total life cycle of the product. In this study a life cycle analysis has been applied, according to the so-called quick-scan method. A comparison has been made between letting lie fallow agricultural areas and using such grounds for the production of RME. The analysis is made from the RME production up to and including the use of the bio-diesel fuel in a diesel engine. The economic analysis has been carried out by means of spread-sheet models on the level of cultivation businesses and the relevant sector. The impacts on the macro-economy are analyzed via input and output tables, deducted from models of the Dutch Central Bureau for Statistics (CBS) and the Dutch Central Planning Bureau (CPB). Also a number of sensitivity analysis has been executed. 4 figs., 5 tabs., 6 appendices, 45 refs

  4. Mission analysis of photovoltaic solar energy systems. Quarterly progress report, 1 March 1976-31 May 1976

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, S.L.; Munjal, P.K.; Rattin, E.J.

    1976-06-01

    The main emphasis of the activity during the second quarter of this project continued to be on Task 1, Analysis of Near-Term Missions, and on Task 2, Analysis of Major Mid-Term Missions. In addition, considerable progress was also made on Task 6, Comparison of the True Societal Costs of Conventional and Photovoltaic Power Production, and starts were made on Task 3, Review and Updating of the ERDA Technology Implementation Plan, and Task 4, Critical External Issues. As was planned, work on Task 5, Impact of Incentives, was deferred to the second half of the program. Progress is reported. (WHK)

  5. Progress in Addressing DNFSB Recommendation 2002-1 Issues: Improving Accident Analysis Software Applications

    Energy Technology Data Exchange (ETDEWEB)

    VINCENT, ANDREW

    2005-04-25

    Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2002-1 (''Quality Assurance for Safety-Related Software'') identified a number of quality assurance issues on the use of software in Department of Energy (DOE) facilities for analyzing hazards, and designing and operating controls to prevent or mitigate potential accidents. Over the last year, DOE has begun several processes and programs as part of the Implementation Plan commitments, and in particular, has made significant progress in addressing several sets of issues particularly important in the application of software for performing hazard and accident analysis. The work discussed here demonstrates that through these actions, Software Quality Assurance (SQA) guidance and software tools are available that can be used to improve resulting safety analysis. Specifically, five of the primary actions corresponding to the commitments made in the Implementation Plan to Recommendation 2002-1 are identified and discussed in this paper. Included are the web-based DOE SQA Knowledge Portal and the Central Registry, guidance and gap analysis reports, electronic bulletin board and discussion forum, and a DOE safety software guide. These SQA products can benefit DOE safety contractors in the development of hazard and accident analysis by precluding inappropriate software applications and utilizing best practices when incorporating software results to safety basis documentation. The improvement actions discussed here mark a beginning to establishing stronger, standard-compliant programs, practices, and processes in SQA among safety software users, managers, and reviewers throughout the DOE Complex. Additional effort is needed, however, particularly in: (1) processes to add new software applications to the DOE Safety Software Toolbox; (2) improving the effectiveness of software issue communication; and (3) promoting a safety software quality assurance culture.

  6. Progress in Addressing DNFSB Recommendation 2002-1 Issues: Improving Accident Analysis Software Applications

    International Nuclear Information System (INIS)

    Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2002-1 (''Quality Assurance for Safety-Related Software'') identified a number of quality assurance issues on the use of software in Department of Energy (DOE) facilities for analyzing hazards, and designing and operating controls to prevent or mitigate potential accidents. Over the last year, DOE has begun several processes and programs as part of the Implementation Plan commitments, and in particular, has made significant progress in addressing several sets of issues particularly important in the application of software for performing hazard and accident analysis. The work discussed here demonstrates that through these actions, Software Quality Assurance (SQA) guidance and software tools are available that can be used to improve resulting safety analysis. Specifically, five of the primary actions corresponding to the commitments made in the Implementation Plan to Recommendation 2002-1 are identified and discussed in this paper. Included are the web-based DOE SQA Knowledge Portal and the Central Registry, guidance and gap analysis reports, electronic bulletin board and discussion forum, and a DOE safety software guide. These SQA products can benefit DOE safety contractors in the development of hazard and accident analysis by precluding inappropriate software applications and utilizing best practices when incorporating software results to safety basis documentation. The improvement actions discussed here mark a beginning to establishing stronger, standard-compliant programs, practices, and processes in SQA among safety software users, managers, and reviewers throughout the DOE Complex. Additional effort is needed, however, particularly in: (1) processes to add new software applications to the DOE Safety Software Toolbox; (2) improving the effectiveness of software issue communication; and (3) promoting a safety software quality assurance culture

  7. Final Hazard Classification and Auditable Safety Analysis for the N Basin Segment

    International Nuclear Information System (INIS)

    The purposes of this report are to serve as the auditable safety analysis (ASA) for the N Basin Segment, during surveillance and maintenance preceding decontamination and decommissioning; to determine and document the final hazard classification (FHC) for the N Basin Segment. The result of the ASA evaluation are: based on hazard analyses and the evaluation of accidents, no activity could credibly result in an unacceptable exposure to an individual; controls are identified that serve to protect worker health and safety. The results of the FHC evaluation are: potential exposure is much below 10 rem (0.46 rem), and the FHC for the N Basin Segment is Radiological

  8. ITER final design report, cost review and safety analysis (FDR) and relevant documents

    International Nuclear Information System (INIS)

    This volume contains the fourth major milestone report and documents associated with its acceptance, review and approval. This ITER Final Design Report, Cost Review and Safety Analysis was presented to the ITER Council at its 13th meeting in February 1998 and was approved at its extraordinary meeting on 25 June 1998. The contents include an outline of the ITER objectives, the ITER parameters and design overview as well as operating scenarios and plasma performance. Furthermore, design features, safety and environmental characteristics and schedule and cost estimates are given

  9. Auditable safety analysis and final hazard classification for Buildings 1310-N and 1314-N

    International Nuclear Information System (INIS)

    This document is a graded auditable safety analysis (ASA) of the deactivation activities planned for the 100-N facility segment comprised of the Building 1310-N pump silo (part of the Liquid Radioactive Waste Treatment Facility) and 1314-N Building (Liquid Waste Disposal Building).The ASA describes the hazards within the facility and evaluates the adequacy of the measures taken to reduce, control, or mitigate the identified hazards. This document also serves as the Final Hazard Classification (FHC) for the 1310-N pump silo and 1314-N Building segment. The FHC is radiological based on the Preliminary Hazard Classification and the total inventory of radioactive and hazardous materials in the segment

  10. Analysis scheme of the PISC-2 trials results PISC 2 report No. 4. Final issue

    International Nuclear Information System (INIS)

    Ultrasonic testing is widely used for detecting, locating and sizing flaws in primary circuit elements at various stages of plant life. The successive PISC projects have constituted the most notable sustained international effort to assess the effectiveness of these inspection techniques. The Plate Inspection Steering Committee (PISC-I) programme (1976-1980) was intended to establish the capabilities of the 1974 ASME Code Section XI ultrasonic procedure. The Programme for the Inspection of Steel Components (PISC-II, 1981-1986) constitutes a more profound evaluation of the best performance obtainable by modern ultrasonic techniques under optimal conditions. The total amount of data generated by the round-robin tests being extremely large, it has been necessary to establish an overall strategy for the data analysis that looks at the data in progressively increasing details. Three levels of analysis were established to handle the RRT data: Global or Team Level, Procedure level, Technique level. The various sections of this report are: data provided by the RRT, the data analysis scheme, the definition of analysis parameters, and the method of presentation of results

  11. Multi-task linear programming discriminant analysis for the identification of progressive MCI individuals.

    Directory of Open Access Journals (Sweden)

    Guan Yu

    Full Text Available Accurately identifying mild cognitive impairment (MCI individuals who will progress to Alzheimer's disease (AD is very important for making early interventions. Many classification methods focus on integrating multiple imaging modalities such as magnetic resonance imaging (MRI and fluorodeoxyglucose positron emission tomography (FDG-PET. However, the main challenge for MCI classification using multiple imaging modalities is the existence of a lot of missing data in many subjects. For example, in the Alzheimer's Disease Neuroimaging Initiative (ADNI study, almost half of the subjects do not have PET images. In this paper, we propose a new and flexible binary classification method, namely Multi-task Linear Programming Discriminant (MLPD analysis, for the incomplete multi-source feature learning. Specifically, we decompose the classification problem into different classification tasks, i.e., one for each combination of available data sources. To solve all different classification tasks jointly, our proposed MLPD method links them together by constraining them to achieve the similar estimated mean difference between the two classes (under classification for those shared features. Compared with the state-of-the-art incomplete Multi-Source Feature (iMSF learning method, instead of constraining different classification tasks to choose a common feature subset for those shared features, MLPD can flexibly and adaptively choose different feature subsets for different classification tasks. Furthermore, our proposed MLPD method can be efficiently implemented by linear programming. To validate our MLPD method, we perform experiments on the ADNI baseline dataset with the incomplete MRI and PET images from 167 progressive MCI (pMCI subjects and 226 stable MCI (sMCI subjects. We further compared our method with the iMSF method (using incomplete MRI and PET images and also the single-task classification method (using only MRI or only subjects with both MRI and

  12. Late-phase melt progression experiment: MP-2. Results and analysis

    International Nuclear Information System (INIS)

    In-pile experiments addressing late-phase processes in Light Water Reactors (LWRs) were performed in the Annular Core Research Reactor (ACRR) at Sandia National Laboratories. Melt Progression (MP) experiments were designed to provide information to develop and verify computer models for analysis of LWR core damage in severe accidents. Experiments examine the formation and motion of ceramic molten pools in disrupted reactor core regions. The MP-2 experiment assembly consisted of: (1) a rubble bed of enriched UO2 and ZrO2 simulating severely disrupted reactor core regions, (2) a ceramic/metallic crust representing blockage formed by early phase melting, relocation, and refreezing of core components, and (3) an intact rod stub region that remained in place below the blockage region. The test assembly was fission heated in the central cavity of the ACRR at an average rate of about 0.2 KA, reaching a peak molten pool temperature around 3400 K. Melting of the debris bed ceramic components was initiated near the center of the bed. The molten material relocated downward, refreezing to form a ceramic crust near the bottom of the rubble bed. As power levels were increased, the crust gradually remelted and reformed at progressively lower positions in the bed until late in the experiment when it penetrated into and attacked the ceramic/metallic blockage. The metallic components of the blockage region melted and relocated to the bottom of the intact rod stub region before the ceramic melt penetrated the blockage region from above. The ceramic pool penetrated halfway into the blockage region by the end of the experiment. Measurements of thermal response and material relocation are compared to the results of the computer simulations. Postexperiment examination of the assembly with the associated material interactions and metallurgy are also discussed in detail with the analyses and interpretation of results. 16 refs., 206 figs., 24 tabs

  13. A three-dimensional finite element analysis of the osseointegration progression in the human mandible

    Science.gov (United States)

    Esmail, Enas; Hassan, Noha; Kadah, Yasser

    2010-02-01

    In this study, three-dimensional (3D) finite element analysis was used to model the effect of the peri-implant bone geometry and thickness on the biomechanical behavior of a dental implant/supporting bone system. The 3D finite element model of the jaw bone, cancellous and cortical, was developed based on computerized tomography (CT) scan technology while the dental implant model was created based on a commercially available implant design. Two models, cylindrical and threaded, representing the peri-implant bone region were simulated. In addition, various thicknesses (0.1 mm, 0.3 mm, 0.5 mm) of the peri-implant bone region were modeled to account for the misalingnment during the drilling process. Different biomechanical properties of the peri-implant bone region were used to simulate the progression of the osseointegration process with time. Four stages of osseointegration were modeled to mimic different phases of tissue healing of the peri- implant region starting with soft connective tissue and ending with complete bone maturation. For the realistic threaded model of the peri-implant bone region, the maximum von Mises stress and displacement in the dental implant and jaw bone were higher than those computed for the simple cylindrical peri-implant bone region model. The average von Mises stress and displacement in the dental implant and the jaw bone decreased as the oseeointegration progressed with time for all thicknesses of the peri-implant bone region. On the other hand, the maximum absolute vertical displacement of the dental implant increased as the drilled thickness of the peri-implant bone region increased.

  14. Late-phase melt progression experiment: MP-2. Results and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Gasser, R.D.; Gauntt, R.O.; Bourcier, S.C. [and others

    1997-05-01

    In-pile experiments addressing late-phase processes in Light Water Reactors (LWRs) were performed in the Annular Core Research Reactor (ACRR) at Sandia National Laboratories. Melt Progression (MP) experiments were designed to provide information to develop and verify computer models for analysis of LWR core damage in severe accidents. Experiments examine the formation and motion of ceramic molten pools in disrupted reactor core regions. The MP-2 experiment assembly consisted of: (1) a rubble bed of enriched UO{sub 2} and ZrO{sub 2} simulating severely disrupted reactor core regions, (2) a ceramic/metallic crust representing blockage formed by early phase melting, relocation, and refreezing of core components, and (3) an intact rod stub region that remained in place below the blockage region. The test assembly was fission heated in the central cavity of the ACRR at an average rate of about 0.2 KA, reaching a peak molten pool temperature around 3400 K. Melting of the debris bed ceramic components was initiated near the center of the bed. The molten material relocated downward, refreezing to form a ceramic crust near the bottom of the rubble bed. As power levels were increased, the crust gradually remelted and reformed at progressively lower positions in the bed until late in the experiment when it penetrated into and attacked the ceramic/metallic blockage. The metallic components of the blockage region melted and relocated to the bottom of the intact rod stub region before the ceramic melt penetrated the blockage region from above. The ceramic pool penetrated halfway into the blockage region by the end of the experiment. Measurements of thermal response and material relocation are compared to the results of the computer simulations. Postexperiment examination of the assembly with the associated material interactions and metallurgy are also discussed in detail with the analyses and interpretation of results. 16 refs., 206 figs., 24 tabs.

  15. Recent progress on the development and analysis of the ITPA global H-mode confinement database

    International Nuclear Information System (INIS)

    This paper describes the updates to and analysis of the International Tokamak Physics Activity (ITPA) Global H-Mode Confinement Database version 3 (DB3) over the period 1994-2004. Global data, for the energy confinement time and its controlling parameters, have now been collected from 18 machines of different sizes and shapes: ASDEX, ASDEX Upgrade, C-Mod, COMPASS-D, DIII-D, JET, JFT-2M, JT-60U, MAST, NSTX, PBX-M, PDX, START, T-10, TCV, TdeV, TFTR and TUMAN-3M. The database now contains 10382 data entries from 3762 plasma discharges, including data from deuterium-tritium experiments, low-aspect ratio plasmas, dimensionless parameter experiments and plasmas. DB3 also contains an increased amount of data from a range of diverted machines and further data at high triangularity, high density and high current. A wide range of physics studies has been performed on DB3 with particular progress made in the separation of core and edge behaviour, dimensionless parameter analyses and the comparison of the database with one-dimensional transport codes. The errors in the physics variables of the database have also been studied and this has led to the use of errors in variables fits. A key aim of the database has always been to provide a basis for estimating the energy confinement properties of next step machines such as ITER, and so the impact of the database and its analysis on such machines is also discussed

  16. Optics analysis of Final Focus Test Beam with the help of methods based on Lie algebra

    International Nuclear Information System (INIS)

    The Final Focus Test Beam being built at SLAC is a test bed for future linear collider final focus systems. The parameters and the optics of the FFTB are presented in chapter one. The mathematical tools for this thesis which are based on Lie algebras are then reviewed in chapter two. One relies particularly on the Lie transformations together with the similarity transformation and the Campbell-Baler-Haussdorff theorem for the manipulation of Hamiltonians. Chapter three presents the application of these methods to magnetic optics in accelerators; the separation of linear and non-linear effects and the building of the total Hamiltonian of the line from the thin-lens formulation. Chapter four analytically establishes a catalog of aberrations, up to order five in the Hamiltonians, at the FFTB. The emphasis is put on the methods of analysis. It is shown that the system has a significant fifth-order aberration and that no higher-order aberration appears. Finally chapter six presents some stability tolerances - alignment strength and multipole content - for the FFTB. In the conclusion the present situation of these methods, as well as possible computer codes using them, are reviewed

  17. A STATISTICAL ANALYSIS OF GDP AND FINAL CONSUMPTION USING SIMPLE LINEAR REGRESSION. THE CASE OF ROMANIA 1990–2010

    OpenAIRE

    Aniela Balacescu; Marian Zaharia

    2011-01-01

    This paper aims to examine the causal relationship between GDP and final consumption. The authors used linear regression model in which GDP is considered variable results, and final consumption variable factor. In drafting article we used Excel software application that is a modern computing and statistical data analysis.

  18. Seismic risk analysis for General Electric Plutonium Facility, Pleasanton, California. Final report, part II

    Energy Technology Data Exchange (ETDEWEB)

    1980-06-27

    This report is the second of a two part study addressing the seismic risk or hazard of the special nuclear materials (SNM) facility of the General Electric Vallecitos Nuclear Center at Pleasanton, California. The Part I companion to this report, dated July 31, 1978, presented the seismic hazard at the site that resulted from exposure to earthquakes on the Calaveras, Hayward, San Andreas and, additionally, from smaller unassociated earthquakes that could not be attributed to these specific faults. However, while this study was in progress, certain additional geologic information became available that could be interpreted in terms of the existance of a nearby fault. Although substantial geologic investigations were subsequently deployed, the existance of this postulated fault, called the Verona Fault, remained very controversial. The purpose of the Part II study was to assume the existance of such a capable fault and, under this assumption, to examine the loads that the fault could impose on the SNM facility. This report first reviews the geologic setting with a focus on specifying sufficient geologic parameters to characterize the postulated fault. The report next presents the methodology used to calculate the vibratory ground motion hazard. Because of the complexity of the fault geometry, a slightly different methodology is used here compared to the Part I report. This section ends with the results of the calculation applied to the SNM facility. Finally, the report presents the methodology and results of the rupture hazard calculation.

  19. Quench front progression in a superheated porous medium: experimental analysis and model development

    International Nuclear Information System (INIS)

    In case of severe accident in a nuclear reactor, the fuel rods may be highly damaged and oxidized and finally collapse to form a debris bed. Removal of decay heat from a debris bed is a challenging issue because of the difficulty for water to flow inside. Currently, IRSN has started experimental program PEARL with two experimental facilities PRELUDE and PEARL, to investigate the reflood process at high temperature, for various particle sizes. On the basis of PRELUDE experimental results, the thermal hydraulic features of the quench front have been analysed and the intensity of heat transfers was estimated. From a selection of experimental results, a reflooding model was improved and validated. The model is implemented in the code ICARE-CATHARE developed by IRSN which is used for severe accident reactor analysis. (author)

  20. Plant incident progress scenario analysis for nuclear emergency exercise of Kansai Electric Power Co., Inc. in fiscal 2011

    International Nuclear Information System (INIS)

    In the light of the lessons learned from the accident at Fukushima dai-ichi nuclear power plant, the Kansai Electric Power Company (KEPCO) has developed various emergency safety measures in order to restore cooling functions in the nuclear power plants (NPPs) while preventing reactor core or spent fuel damages and containing radioactive releases even in the case that all the three safety functions (all AC power sources, seawater cooling and spent fuel pit (SFP) cooling functions) are lost due to a tsunami. A nuclear emergency exercise of KEPCO, which was intended for Ohi-1-4, was held in fiscal 2011 for an evaluation of the emergency plan. The scenario of the exercise was as follows: Ohi units 1, 2 and 3 in operation scrammed automatically due to an earthquake. At that time, Ohi unit 4 was under periodic inspection. Then, an earthquake-induced tsunami hit the NPPs. Finally, all of Ohi NPPs fell into station black out (SBO) and the cooling systems totally lost their function. In addition, the turbine driven auxiliary feed water pump did not work in Ohi unit 3, thus water supply to the steam generators (SGs) was lost. In this paper, the scenario which is postulated for emergency exercise is analyzed with the MAAP4 code in order to assist the nuclear emergency exercise of KEPCO in fiscal 2011. Then, the incident progress of the postulated scenario is evaluated on the basis of the analysis results, including the time of the occurrence of specified events based on the Nuclear Disaster Special Measures Law and main events. The results indicate that it is possible to terminate the event without core damage for the postulated scenario. (author)

  1. Towards a final analysis of lateral gauge use across the stress ranges

    Science.gov (United States)

    McDonald, S. A.; Bourne, N. K.; Millett, J. C. F.; Rosenberg, Z.,

    2015-06-01

    The non-invasive measurement of in-material states of stress and strain within loaded targets is a paradigm that has yet to be achieved. However great advances have been made in achieving this goal over the past thirty years. Advances have come in several areas. Firstly the gauge element was redesigned from a grid configuration to a T shaped wire or foil. Secondly the flow around the gauge was investigated by several workers numerically and experimentally and shown to be stable and tracking vital changes in state faithfully. Finally a staged refinement of the analysis used to deconvolve the change in resistance back to stress has given a device now fit for use as a fiducial over the range of stresses up to the weak shock limit. This work allows examination of a series of features hitherto uncommented that have been noted on the response of the elements. One of these concerns the tracking of elastic-plastic transitions in target materials due to the rapid gauge response in the new geometry. Finally the parallel analysis of material strength using the deconvolution due to Asay has shown agreement and differences between the two techniques which are noted and reconciled here.

  2. Progressive Collapse Analysis of Two Existing Steel Buildings Using Linear Static Procedure

    OpenAIRE

    Larijani, Reza Jalali

    2012-01-01

    ABSTRACT: There are numerous threats which could cause progressive collapse in a structure that may lead to fatality. After the incident in Oklahoma Murrah building and the recent terrorist attacks, such as WTC (World Trade Center) in 2001, it became more important to do assessment towards preventing the progressive collapse. Although, there have been many researches carried out on progressive collapse, the increase in terrorist attacks, especially loss of lives (nearly 3000 died in the atta...

  3. Does monitoring goal progress promote goal attainment? A meta-analysis of the experimental evidence.

    Science.gov (United States)

    Harkin, Benjamin; Webb, Thomas L; Chang, Betty P I; Prestwich, Andrew; Conner, Mark; Kellar, Ian; Benn, Yael; Sheeran, Paschal

    2016-02-01

    Control theory and other frameworks for understanding self-regulation suggest that monitoring goal progress is a crucial process that intervenes between setting and attaining a goal, and helps to ensure that goals are translated into action. However, the impact of progress monitoring interventions on rates of behavioral performance and goal attainment has yet to be quantified. A systematic literature search identified 138 studies (N = 19,951) that randomly allocated participants to an intervention designed to promote monitoring of goal progress versus a control condition. All studies reported the effects of the treatment on (a) the frequency of progress monitoring and (b) subsequent goal attainment. A random effects model revealed that, on average, interventions were successful at increasing the frequency of monitoring goal progress (d+ = 1.98, 95% CI [1.71, 2.24]) and promoted goal attainment (d+ = 0.40, 95% CI [0.32, 0.48]). Furthermore, changes in the frequency of progress monitoring mediated the effect of the interventions on goal attainment. Moderation tests revealed that progress monitoring had larger effects on goal attainment when the outcomes were reported or made public, and when the information was physically recorded. Taken together, the findings suggest that monitoring goal progress is an effective self-regulation strategy, and that interventions that increase the frequency of progress monitoring are likely to promote behavior change. PMID:26479070

  4. Reliability of steam-turbine rotors. Task 1. Lifetime prediction analysis system. Final report

    International Nuclear Information System (INIS)

    Task 1 of RP 502, Reliability of Steam Turbine Rotors, resulted in the development of a computerized lifetime prediction analysis system (STRAP) for the automatic evaluation of rotor integrity based upon the results of a boresonic examination of near-bore defects. Concurrently an advanced boresonic examination system (TREES), designed to acquire data automatically for lifetime analysis, was developed and delivered to the maintenance shop of a major utility. This system and a semi-automated, state-of-the-art system (BUCS) were evaluated on two retired rotors as part of the Task 2 effort. A modified nonproprietary version of STRAP, called SAFER, is now available for rotor lifetime prediction analysis. STRAP and SAFER share a common fracture analysis postprocessor for rapid evaluation of either conventional boresonic amplitude data or TREES cell data. The final version of this postprocessor contains general stress intensity correlations for elliptical cracks in a radial stress gradient and provision for elastic-plastic instability of the ligament between an imbedded crack and the bore surface. Both linear elastic and ligament rupture models were developed for rapid analysis of linkup within three-dimensional clusters of defects. Bore stress-rupture criteria are included, but a creep-fatigue crack growth data base is not available. Physical and mechanical properties of air-melt 1CrMoV forgings are built into the program; however, only bounding values of fracture toughness versus temperature are available. Owing to the lack of data regarding the probability of flaw detection for the boresonic systems and of quantitative verification of the flaw linkup analysis, automatic evlauation of boresonic results is not recommended, and the lifetime prediction system is currently restricted to conservative, deterministic analysis of specified flaw geometries

  5. The fuzzy set theory application to the analysis of accident progression event trees with phenomenological uncertainty issues

    International Nuclear Information System (INIS)

    Fuzzy set theory provides a formal framework for dealing with the imprecision and vagueness inherent in the expert judgement, and therefore it can be used for more effective analysis of accident progression of PRA where experts opinion is a major means for quantifying some event probabilities and uncertainties. In this paper, an example application of the fuzzy set theory is first made to a simple portion of a given accident progression event tree with typical qualitative fuzzy input data, and thereby computational algorithms suitable for application of the fuzzy set theory to the accident progression event tree analysis are identified and illustrated with example applications. Then the procedure used in the simple example is extended to extremely complex accident progression event trees with a number of phenomenological uncertainty issues, i.e., a typical plant damage state 'SEC' of the Zion Nuclear Power Plant risk assessment. The results show that the fuzzy averages of the fuzzy outcomes are very close to the mean values obtained by current methods. The main purpose of this paper is to provide a formal procedure for application of the fuzzy set theory to accident progression event trees with imprecise and qualitative branch probabilities and/or with a number of phenomenological uncertainty issues. (author)

  6. Cerebral glucose metabolism in corticobasal degeneration comparison with progressive supranuclear palsy using statistical mapping analysis.

    Science.gov (United States)

    Juh, Rahyeong; Pae, Chi-Un; Kim, Tae-Suk; Lee, Chang-Uk; Choe, Boyoung; Suh, Taesuk

    This study measured the cerebral glucose metabolism in patients suffering from corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP). The aim was to determine if there is a different metabolic pattern using (18)F-labeled 2-deoxyglucose ((18)F-FDG) positron emission tomography (PET). The regional cerebral glucose metabolism was examined in 8 patients diagnosed clinically with CBD (mean age 69.6 +/- 7.8 years; male/female: 5/3), 8 patients with probable PSP (mean age 67.8 +/- 4.5 years; male/female: 4/4) and 22 healthy controls. The regional cerebral glucose metabolism between the three groups was compared using statistical parametric mapping (SPM) with a voxel-by-voxel approach (p < 0.001, 200-voxel level). Compared with the normal controls, asymmetry in the regional glucose metabolism was observed in the parietal, frontal and cingulate in the CBD patients. In the PSP patients, the glucose metabolism was lower in the orbitofrontal, middle frontal, cingulate, thalamus and mid-brain than their age matched normal controls. A comparison of the two patient groups demonstrated relative hypometabolism in the thalamus, the mid-brain in the PSP patients and the parietal lobe in CBD patients. These results suggest that when making a differential diagnosis of CBD and PSP, voxel-based analysis of the (18)F-FDG PET images using a SPM might be a useful tool in clinical examinations. PMID:15936506

  7. Recent progress on fingerprint visualization and analysis by imaging ridge residue components.

    Science.gov (United States)

    Su, Bin

    2016-04-01

    Fingerprints have long been and are still considered to be the gold standard for personal identification in forensic investigations. Developing or enhancing the visualization of invisible fingerprints, so-called latent fingerprints (LFPs), remains to be the core subject in forensic science. Moreover, the past few years have witnessed a renewal of research interest in the possibility that a fingerprint can provide additional information than just identification of individuals, such as personal traits, the presence of human metabolites with diagnostic values, and the evidence of contact with explosives or illicit drugs. Fingerprint analysis has manifested itself as a research area far beyond the scope of forensics, to which not only conventional fingerprint examiners but also researchers from chemistry, biochemistry, medical science, material science, and nanotechnology fields have made significant contributions in recent years. Beginning with a brief overview of the components present in LFP residue that essentially determines which method or reagent will give the best visualization result, this paper reviews the progress since 2007 on new reagents and methods developed for LFP visualization and simultaneous detection of specific chemicals present in the LFP residue, with an emphasis on the utilization of mass spectrometry, infrared spectroscopy, nanoparticles, and immunogenic and nucleic acid reagents. PMID:26781104

  8. Interface Finite Elements for the Analysis of Fracture Initiation and Progression

    Science.gov (United States)

    Ambur, Damodar R. (Technical Monitor); Johnson, Eric R.

    2003-01-01

    Progressive failure analyses (PFA) are important for the prediction of residual strength and damage tolerance of vehicle structures, and to predict the energy absorbing capability of vehicle structures under crash-type loads. Typically continuum damage mechanics (CDM) and fracture mechanics (FM) are the methods used for PFA. The method of interfacial damage mechanics (IDM) is used for PFA in this research. IDM has capabilities intermediate between CDM and FM, and is used to numerically model the initiation, growth, and arrest of cracks. IDM smooths the stress singularity at the crack tip, and is easily adaptable with other nonlinearties such as plasticity and material damage. IDM is implemented by user-defined interface elements in the ABAQUS/ Standard structural analysis software package. The structural components selected to demonstrate the effectiveness PFA using interface elements are, for the most part, those with published test data. These structural components were subjected to quasi-static loading in the tests. Thus, the ABAQUS analyses are used to predict geometrically and materially nonlinear equilibrium states. Impact loading, dynamic fracture, reflected stress waves, inertia, and time dependent material behavior are not considered.

  9. Mapping cancer cell metabolism with 13 C flux analysis: Recent progress and future challenges

    Directory of Open Access Journals (Sweden)

    Casey Scott Duckwall

    2013-01-01

    Full Text Available The reprogramming of energy metabolism is emerging as an important molecular hallmark of cancer cells. Recent discoveries linking specific metabolic alterations to cancer development have strengthened the idea that altered metabolism is more than a side effect of malignant transformation, but may in fact be a functional driver of tumor growth and progression in some cancers. As a result, dysregulated metabolic pathways have become attractive targets for cancer therapeutics. This review highlights the application of 13 C metabolic flux analysis (MFA to map the flow of carbon through intracellular biochemical pathways of cancer cells. We summarize several recent applications of MFA that have identified novel biosynthetic pathways involved in cancer cell proliferation and shed light on the role of specific oncogenes in regulating these pathways. Through such studies, it has become apparent that the metabolic phenotypes of cancer cells are not as homogeneous as once thought, but instead depend strongly on the molecular alterations and environmental factors at play in each case.

  10. Genetic study of autosomal dominant progressive external ophthalmoplegia and familial myasthenia gravis : linkage analysis, candidate gene cloning and mutation detection

    OpenAIRE

    Li, Fang-Yuan

    2001-01-01

    Identification of genes responsible for familial human diseases is a major task of medical genetics. In this process, linkage analysis, candidate gene screening and mutation detection are the three major steps (Paper I-VI). The purpose of this study was to elucidate the genetic backgrounds of autosomal dominant progressive external ophthalmoplegia (adPEO) and familial inyasthenia gravis (FMG). The methods applied in this study for linkage analysis and repeat expansion we...

  11. Effect of atorvastatin on glycaemia progression in patients with diabetes: an analysis from the Collaborative Atorvastatin in Diabetes Trial (CARDS)

    OpenAIRE

    Livingstone, Shona J.; Looker, Helen C.; Akbar, Tahira; Betteridge, D. John; Durrington, Paul N.; Hitman, Graham A.; Neil, H Andrew W; Fuller, John H.; Colhoun, Helen M.

    2015-01-01

    Aims/hypothesis In an individual-level analysis we examined the effect of atorvastatin on glycaemia progression in type 2 diabetes and whether glycaemia effects reduce the prevention of cardiovascular disease (CVD) with atorvastatin. Methods The study population comprised 2,739 people taking part in the Collaborative Atorvastatin Diabetes Study (CARDS) who were randomised to receive atorvastatin 10 mg or placebo and who had post-randomisation HbA1c data. This secondary analysis used Cox regre...

  12. The analysis of factors associated with progression of isolated terminal ileal lesions.

    Directory of Open Access Journals (Sweden)

    Zhang Fangbin

    Full Text Available To assess the factors associated with the progression of isolated terminal ileal lesions (ITILs at colonoscopy in Chinese patients.Patients diagnosed with ITILs were enrolled. The ileoscopy was performed by two experienced gastroenterologists every 52 weeks. A logistic regression analysis was used to elucidate the factors associated with Crohn's disease (CD and mucosal healing. A log rank test was used to assess the differences of the cumulative proportion of CD and mucosal healing in different groups at different times.(1 A total of 34 patients were included and no patient had taken nonsteroidal anti-inflammatory drug in the last 6 months; eight (23.5% patients had a clinical diagnosis of CD, 14 (41.2% patients achieved mucosal healing, and 12 (35.3% patients showed no significant changes in the lesions at last follow-up. (2 The logistic regression analysis showed that only abdominal pain was a factor in the ITIL disease outcomes. (3 The cumulative proportion of CD in the abdominal pain group after 3 years was statistically higher than that in the non-abdominal pain group (42.7% vs. 6.2%, χ2 = 10.129, P = 0.001. However, the cumulative proportion of mucosal healing in the non-abdominal pain group was statistically higher than that in the abdominal pain group (73.3% vs. 5.6%, χ2 = 5.225, P = 0.022. (4 The numbers of lesions observed on the initial colonoscopy exams and the initial histologic findings were not related to the ITIL disease outcomes.Clinical symptoms may be related to ITIL disease outcomes. Patients with abdominal pain had a high likelihood of CD, whereas those without abdominal pain had a high likelihood of mucosal healing.

  13. Transcriptomic changes in human breast cancer progression as determined by serial analysis of gene expression

    International Nuclear Information System (INIS)

    Genomic and transcriptomic alterations affecting key cellular processes such us cell proliferation, differentiation and genomic stability are considered crucial for the development and progression of cancer. Most invasive breast carcinomas are known to derive from precursor in situ lesions. It is proposed that major global expression abnormalities occur in the transition from normal to premalignant stages and further progression to invasive stages. Serial analysis of gene expression (SAGE) was employed to generate a comprehensive global gene expression profile of the major changes occurring during breast cancer malignant evolution. In the present study we combined various normal and tumor SAGE libraries available in the public domain with sets of breast cancer SAGE libraries recently generated and sequenced in our laboratory. A recently developed modified t test was used to detect the genes differentially expressed. We accumulated a total of approximately 1.7 million breast tissue-specific SAGE tags and monitored the behavior of more than 25,157 genes during early breast carcinogenesis. We detected 52 transcripts commonly deregulated across the board when comparing normal tissue with ductal carcinoma in situ, and 149 transcripts when comparing ductal carcinoma in situ with invasive ductal carcinoma (P < 0.01). A major novelty of our study was the use of a statistical method that correctly accounts for the intra-SAGE and inter-SAGE library sources of variation. The most useful result of applying this modified t statistics beta binomial test is the identification of genes and gene families commonly deregulated across samples within each specific stage in the transition from normal to preinvasive and invasive stages of breast cancer development. Most of the gene expression abnormalities detected at the in situ stage were related to specific genes in charge of regulating the proper homeostasis between cell death and cell proliferation. The comparison of in situ lesions

  14. Identification of Major Signaling Pathways in Prion Disease Progression Using Network Analysis.

    Science.gov (United States)

    Newaz, Khalique; Sriram, K; Bera, Debajyoti

    2015-01-01

    Prion diseases are transmissible neurodegenerative diseases that arise due to conformational change of normal, cellular prion protein (PrPC) to protease-resistant isofrom (rPrPSc). Deposition of misfolded PrpSc proteins leads to an alteration of many signaling pathways that includes immunological and apoptotic pathways. As a result, this culminates in the dysfunction and death of neuronal cells. Earlier works on transcriptomic studies have revealed some affected pathways, but it is not clear which is (are) the prime network pathway(s) that change during the disease progression and how these pathways are involved in crosstalks with each other from the time of incubation to clinical death. We perform network analysis on large-scale transcriptomic data of differentially expressed genes obtained from whole brain in six different mouse strain-prion strain combination models to determine the pathways involved in prion diseases, and to understand the role of crosstalks in disease propagation. We employ a notion of differential network centrality measures on protein interaction networks to identify the potential biological pathways involved. We also propose a crosstalk ranking method based on dynamic protein interaction networks to identify the core network elements involved in crosstalk with different pathways. We identify 148 DEGs (differentially expressed genes) potentially related to the prion disease progression. Functional association of the identified genes implicates a strong involvement of immunological pathways. We extract a bow-tie structure that is potentially dysregulated in prion disease. We also propose an ODE model for the bow-tie network. Predictions related to diseased condition suggests the downregulation of the core signaling elements (PI3Ks and AKTs) of the bow-tie network. In this work, we show using transcriptomic data that the neuronal dysfunction in prion disease is strongly related to the immunological pathways. We conclude that these

  15. Identification of Major Signaling Pathways in Prion Disease Progression Using Network Analysis.

    Directory of Open Access Journals (Sweden)

    Khalique Newaz

    Full Text Available Prion diseases are transmissible neurodegenerative diseases that arise due to conformational change of normal, cellular prion protein (PrPC to protease-resistant isofrom (rPrPSc. Deposition of misfolded PrpSc proteins leads to an alteration of many signaling pathways that includes immunological and apoptotic pathways. As a result, this culminates in the dysfunction and death of neuronal cells. Earlier works on transcriptomic studies have revealed some affected pathways, but it is not clear which is (are the prime network pathway(s that change during the disease progression and how these pathways are involved in crosstalks with each other from the time of incubation to clinical death. We perform network analysis on large-scale transcriptomic data of differentially expressed genes obtained from whole brain in six different mouse strain-prion strain combination models to determine the pathways involved in prion diseases, and to understand the role of crosstalks in disease propagation. We employ a notion of differential network centrality measures on protein interaction networks to identify the potential biological pathways involved. We also propose a crosstalk ranking method based on dynamic protein interaction networks to identify the core network elements involved in crosstalk with different pathways. We identify 148 DEGs (differentially expressed genes potentially related to the prion disease progression. Functional association of the identified genes implicates a strong involvement of immunological pathways. We extract a bow-tie structure that is potentially dysregulated in prion disease. We also propose an ODE model for the bow-tie network. Predictions related to diseased condition suggests the downregulation of the core signaling elements (PI3Ks and AKTs of the bow-tie network. In this work, we show using transcriptomic data that the neuronal dysfunction in prion disease is strongly related to the immunological pathways. We conclude that

  16. No evidence of real progress in treatment of acute pain, 1993–2012: scientometric analysis

    Directory of Open Access Journals (Sweden)

    Correll DJ

    2014-04-01

    Full Text Available Darin J Correll, Kamen V Vlassakov, Igor Kissin Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA Abstract: Over the past 2 decades, many new techniques and drugs for the treatment of acute pain have achieved widespread use. The main aim of this study was to assess the progress in their implementation using scientometric analysis. The following scientometric indices were used: 1 popularity index, representing the share of articles on a specific technique (or a drug relative to all articles in the field of acute pain; 2 index of change, representing the degree of growth in publications on a topic compared to the previous period; and 3 index of expectations, representing the ratio of the number of articles on a topic in the top 20 journals relative to the number of articles in all (>5,000 biomedical journals covered by PubMed. Publications on specific topics (ten techniques and 21 drugs were assessed during four time periods (1993–1997, 1998–2002, 2003–2007, and 2008–2012. In addition, to determine whether the status of routine acute pain management has improved over the past 20 years, we analyzed surveys designed to be representative of the national population that reflected direct responses of patients reporting pain scores. By the 2008–2012 period, popularity index had reached a substantial level (≥5% only with techniques or drugs that were introduced 30–50 years ago or more (epidural analgesia, patient-controlled analgesia, nerve blocks, epidural analgesia for labor or delivery, bupivacaine, and acetaminophen. In 2008–2012, promising (although modest changes of index of change and index of expectations were found only with dexamethasone. Six national surveys conducted for the past 20 years demonstrated an unacceptably high percentage of patients experiencing moderate or severe pain with not even a trend toward outcome improvement. Thus

  17. Skeletal Plasmacytoma: Progression of disease and impact of local treatment; an analysis of SEER database

    Directory of Open Access Journals (Sweden)

    Scully Sean P

    2009-09-01

    Full Text Available Abstract Background Previous reports suggest an as yet unidentifiable subset of patients with plasmacytoma will progress to myeloma. The current study sought to establish the risk of developing myeloma and determine the prognostic factors affecting the progression of disease. Methods Patients with plasmacytoma diagnosed between 1973 and 2005 were identified in the SEER database(1164 patients. Patient demographics and clinical characteristics, treatment(s, cause of death, and survival were extracted. Kaplan-Meier, log-rank, and Cox regression were used to analyze prognostic factors. Results The five year survival among patients initially diagnosed with plasmacytoma that later progressed to multiple myeloma and those initially diagnosed with multiple myeloma were almost identical (25% and 23%; respectively. Five year survival for patients with plasmacytoma that did not progress to multiple myeloma was significantly better (72%. Age > 60 years was the only factor that correlated with progression of disease (p = 0.027. Discussion Plasmacytoma consists of two cohorts of patients with different overall survival; those patients that do not progress to systemic disease and those that develop myeloma. Age > 60 years is associated with disease progression. Identifying patients with systemic disease early in the treatment will permit aggressive and novel treatment strategies to be implemented.

  18. Barometric pressure transient testing applications at the Nevada Test Site. Nuclear chimney analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hanson, J.M.

    1985-12-01

    Investigations of barometric pressure testing of NTS nuclear chimneys were reviewed. This review includes the models used in the interpretation, methods of analysis, and results. Analytic and semi-analytic models were presented and applied to both historical data and new data taken for this current project. An interpretation technique based on non-linear least squares methods was used to analyze this data in terms of historic and more recent chimney models. Finally, a detailed discussion of radioactive gas transport due to surface barometric pressure fluctuations was presented. This mechanism of transport, referred to as ''barometric pumping,'' is presented in terms of conditions likely to be encountered at the NTS. The report concludes with a discussion of the current understanding of gas flow properties in the alluvial and volcanic areas of the NTS, and suggestions for future efforts directed toward increasing this understanding are presented.

  19. Cost analysis for final disposal of double-shell tank waste

    International Nuclear Information System (INIS)

    The Cost Analysis For Final Disposal of Double-Shell Tank Waste provides the Department of Energy (DOE) and DOE contractors with a better understanding of costs associated with the transfer, storage, and treatment of liquid mixed wasted within the Double-Shell Tank System (DST). In order to evaluate waste minimization/pollution prevention ideas, it is necessary to have reliable cost data that can be used in cost/benefit analyses; preparation of funding requests and/or proposals; and provide a way for prioritizing and allocating limited resources. This cost per gallon rate will be used by DST waste generators to assess the feasibility of Pollution Prevention Opportunity Assessments (P20A) and to determine the cost avoidances or savings associated with the implementation of those P20As

  20. Final safety analysis report for the Galileo Mission: Volume 2, Book 2: Accident model document: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    1988-12-15

    This section of the Accident Model Document (AMD) presents the appendices which describe the various analyses that have been conducted for use in the Galileo Final Safety Analysis Report II, Volume II. Included in these appendices are the approaches, techniques, conditions and assumptions used in the development of the analytical models plus the detailed results of the analyses. Also included in these appendices are summaries of the accidents and their associated probabilities and environment models taken from the Shuttle Data Book (NSTS-08116), plus summaries of the several segments of the recent GPHS safety test program. The information presented in these appendices is used in Section 3.0 of the AMD to develop the Failure/Abort Sequence Trees (FASTs) and to determine the fuel releases (source terms) resulting from the potential Space Shuttle/IUS accidents throughout the missions.

  1. Final hazard classification and auditable safety analysis for the N basin segment

    International Nuclear Information System (INIS)

    The purpose of this report is to provide the following: To serve as the auditable safety analysis (ASA) for the N Basin Segment, including both the quiescent state and planned intrusive activities. The ASA is developed through the realistic evaluation of potential hazards that envelope the threat to personnel. The ASA also includes the specification of the programmatic, baseline, and activity- specific controls that are necessary for the protection of workers. To determine and document the final hazard classification (FHC) for the N Basin Segment. The FHC is developed through the use of bounding accident analyses that envelope the potential exposures to personnel. The FHC also includes the specification of the special controls that are necessary to remain within the envelope of those accident analyses

  2. Analysis of particle sources by interferometry in a three-body final state

    International Nuclear Information System (INIS)

    This work presents the set-up of an original interferometrical method the aim of which is to access the intrinsic parameters (lifetime or natural width) of intermediate resonances created during nuclear collisions. The technic is based on the overlap of two events in the same detection, and shows some analogies with the interferometrical measurements based on the HANBURY-BROWN, TWISS effect. It applies to reactions leading to a three particle final state for which at least two particles are identical. The considered reactions are 11B(α,7Li)αα; 12C(160,α)12C12C, 11B(p,α)αα in which the intermediate source is respectively a level of 11B*, 160*, 8Be*. The results are in qualitative agreement with such an analysis

  3. Barometric pressure transient testing applications at the Nevada Test Site. Nuclear chimney analysis. Final report

    International Nuclear Information System (INIS)

    Investigations of barometric pressure testing of NTS nuclear chimneys were reviewed. This review includes the models used in the interpretation, methods of analysis, and results. Analytic and semi-analytic models were presented and applied to both historical data and new data taken for this current project. An interpretation technique based on non-linear least squares methods was used to analyze this data in terms of historic and more recent chimney models. Finally, a detailed discussion of radioactive gas transport due to surface barometric pressure fluctuations was presented. This mechanism of transport, referred to as ''barometric pumping,'' is presented in terms of conditions likely to be encountered at the NTS. The report concludes with a discussion of the current understanding of gas flow properties in the alluvial and volcanic areas of the NTS, and suggestions for future efforts directed toward increasing this understanding are presented

  4. Cryogen system analysis for the Mirror Fusion Test Facility. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Parmley, R.T.; Hausman, R.F.; Naes, L.G.

    1979-06-01

    The Mirror Fusion Test Facility being designed and constructed at the Lawrence Livermore Laboratory requires a liquid helium liquefaction, storage, distribution, and recovery system and a liquid nitrogen storage and distribution system. To provide a powerful analytical tool to aid in the design evolution of this system through hardware, a thermodynamic fluid flow model was developed. This final report defines the cryogen system that was analyzed (consisting of the LHe subsystem, the GHe recovery subsystem and the LN/sub 2/ subsystem). It details the program assumptions, the theoretical basis for the analysis and limitations of the output. Several parametric runs were performed to illustrate the use of the program. Special detailed analyses were also performed on components such as the recuperator in the helium gas recovery system.

  5. Regulatory analysis for final rule on nuclear power plant license renewal

    International Nuclear Information System (INIS)

    This regulatory analysis provides the supporting information for the final rule (10 CFR Part 54) that defines the Nuclear Regulatory Commission's requirements for renewing the operating licenses of commercial nuclear power plants. A set of four specific alternatives for the safety review of license renewal applications is defined and evaluated. These are: Alternative A-current licensing basis; Alternative B-extension of Alternative A to require assessment and managing of aging; Alternative C -- extension of Alternative B to require assessment of design differences against selected new-plant standards using probabilistic risk assessment; and Alternative D -- extension of Alternative B to require compliance with all new-plant standards. A quantitative comparison of the four alternatives in terms of impact-to-value ratio is presented, and Alternative B is the most cost-beneficial safety review alternative

  6. [Analysis of the progressivity of Brazilian Unified National Health System (SUS) financing].

    Science.gov (United States)

    Ugá, Maria Alicia Domínguez; Santos, Isabela Soares

    2006-08-01

    This article analyzes the level of progressivity in taxes financing the Brazilian Unified National Health System (SUS). Distribution of the tax burden financing the SUS was calculated using micro-data from the Household Budgets Survey, 2002-2003. The Kakwani index, which shows a tax system's level of progressivity, was calculated. The Kakwani index of public financing was -0.008, and SUS financing was nearly proportional to income. From a social justice perspective this is highly undesirable in a society like Brazil, with a Gini index of 0.57. The system should be clearly progressive in order to counterbalance the country's extreme income concentration. PMID:16832531

  7. Impact of HIV Type 1 DNA Levels on Spontaneous Disease Progression: A Meta-Analysis

    DEFF Research Database (Denmark)

    Tsiara, Chrissa G; Nikolopoulos, Georgios K; Bagos, Pantelis G;

    2012-01-01

    Abstract Several studies have reported the prognostic strength of HIV-1 DNA with variable results however. The aims of the current study were to estimate more accurately the ability of HIV-1 DNA to predict progression of HIV-1 disease toward acquired immunodeficiency syndrome (AIDS) or death, and...... primary studies indicated that HIV-1 DNA was a significantly better predictor than HIV-1 RNA of either AIDS alone (ratioof RRs=1.47, 95% CI: 1.05-2.07) or of combined (AIDS or death) progression outcomes (ratio of RRs=1.51, 95% CI: 1.11-2.05). HIV-1 DNA is a strong predictor of HIV-1 disease progression...

  8. Fukushima Daiichi Unit 1 Accident Progression Uncertainty Analysis and Implications for Decommissioning of Fukushima Reactors - Volume I.

    Energy Technology Data Exchange (ETDEWEB)

    Gauntt, Randall O. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Mattie, Patrick D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-01-01

    Sandia National Laboratories (SNL) has conducted an uncertainty analysis (UA) on the Fukushima Daiichi unit (1F1) accident progression with the MELCOR code. The model used was developed for a previous accident reconstruction investigation jointly sponsored by the US Department of Energy (DOE) and Nuclear Regulatory Commission (NRC). That study focused on reconstructing the accident progressions, as postulated by the limited plant data. This work was focused evaluation of uncertainty in core damage progression behavior and its effect on key figures-of-merit (e.g., hydrogen production, reactor damage state, fraction of intact fuel, vessel lower head failure). The primary intent of this study was to characterize the range of predicted damage states in the 1F1 reactor considering state of knowledge uncertainties associated with MELCOR modeling of core damage progression and to generate information that may be useful in informing the decommissioning activities that will be employed to defuel the damaged reactors at the Fukushima Daiichi Nuclear Power Plant. Additionally, core damage progression variability inherent in MELCOR modeling numerics is investigated.

  9. Fukushima Daiichi Unit 1 Accident Progression Uncertainty Analysis and Implications for Decommissioning of Fukushima Reactors - Volume I

    International Nuclear Information System (INIS)

    Sandia National Laboratories (SNL) has conducted an uncertainty analysis (UA) on the Fukushima Daiichi unit (1F1) accident progression with the MELCOR code. The model used was developed for a previous accident reconstruction investigation jointly sponsored by the US Department of Energy (DOE) and Nuclear Regulatory Commission (NRC). That study focused on reconstructing the accident progressions, as postulated by the limited plant data. This work was focused evaluation of uncertainty in core damage progression behavior and its effect on key figures-of-merit (e.g., hydrogen production, reactor damage state, fraction of intact fuel, vessel lower head failure). The primary intent of this study was to characterize the range of predicted damage states in the 1F1 reactor considering state of knowledge uncertainties associated with MELCOR modeling of core damage progression and to generate information that may be useful in informing the decommissioning activities that will be employed to defuel the damaged reactors at the Fukushima Daiichi Nuclear Power Plant. Additionally, core damage progression variability inherent in MELCOR modeling numerics is investigated.

  10. Pion-nucleon partial-wave analysis and study of baryon structure. Final report, June 1, 1981-August 31, 1982

    International Nuclear Information System (INIS)

    This report outlines the progress made in the past 15 months toward completion of a long-term pion-nucleon partial wave analysis in collaboration with R.E. Cuthosky at Carnegie-Mellon University. The report details other theoretical work done during this time period, including work on the Table of Particle Properties, 1982

  11. Morphometric and hemodynamic analysis of atherosclerotic progression in human carotid artery bifurcations.

    Science.gov (United States)

    Huang, Xu; Yin, Xiaoping; Xu, Yingjin; Jia, Xinwei; Li, Jianhui; Niu, Pei; Shen, Wenzeng; Kassab, Ghassan S; Tan, Wenchang; Huo, Yunlong

    2016-03-01

    Although atherosclerosis has been widely investigated at carotid artery bifurcation, there is a lack of morphometric and hemodynamic data at different stages of the disease. The purpose of this study was to determine the lesion difference in patients with carotid artery disease compared with healthy control subjects. The three-dimensional (3D) geometry of carotid artery bifurcation was reconstructed from computed tomography angiography (CTA) images of Chinese control subjects (n = 30) and patients with carotid artery disease (n = 30). We defined two novel vector angles (i.e., angles 1 and 2) that were tangential to the reconstructed contour of the 3D vessel. The best-fit diameter was computed along the internal carotid artery (ICA) center line. Hemodynamic analysis was performed at various bifurcations. Patients with stenotic vessels have larger angles 1 and 2 (151 ± 11° and 42 ± 20°) and smaller diameters of the external carotid artery (ECA) (4.6 ± 0.85 mm) compared with control subjects (144 ± 13° and 36 ± 16°, 5.2 ± 0.57 mm) although there is no significant difference in the common carotid artery (CCA) (7.1 ± 1.2 vs. 7.5 ± 1.0 mm, P = 0.18). In particular, all patients with carotid artery disease have a stenosis at the proximal ICA (including both sinus and carina regions), while 20% of patients have stenosis at the middle ICA and 20% have stenosis expansion to the entire cervical ICA. Morphometric and hemodynamic analyses suggest that atherosclerotic plaques initiate at both sinus and carina regions of ICA and progress downstream. PMID:26747497

  12. Processes regulating progressive nitrogen limitation under elevated carbon dioxide: a meta-analysis

    Science.gov (United States)

    Liang, Junyi; Qi, Xuan; Souza, Lara; Luo, Yiqi

    2016-05-01

    The nitrogen (N) cycle has the potential to regulate climate change through its influence on carbon (C) sequestration. Although extensive research has explored whether or not progressive N limitation (PNL) occurs under CO2 enrichment, a comprehensive assessment of the processes that regulate PNL is still lacking. Here, we quantitatively synthesized the responses of all major processes and pools in the terrestrial N cycle with meta-analysis of CO2 experimental data available in the literature. The results showed that CO2 enrichment significantly increased N sequestration in the plant and litter pools but not in the soil pool, partially supporting one of the basic assumptions in the PNL hypothesis that elevated CO2 results in more N sequestered in organic pools. However, CO2 enrichment significantly increased the N influx via biological N fixation and the loss via N2O emission, but decreased the N efflux via leaching. In addition, no general diminished CO2 fertilization effect on plant growth was observed over time up to the longest experiment of 13 years. Overall, our analyses suggest that the extra N supply by the increased biological N fixation and decreased leaching may potentially alleviate PNL under elevated CO2 conditions in spite of the increases in plant N sequestration and N2O emission. Moreover, our syntheses indicate that CO2 enrichment increases soil ammonium (NH4+) to nitrate (NO3-) ratio. The changed NH4+/NO3- ratio and subsequent biological processes may result in changes in soil microenvironments, above-belowground community structures and associated interactions, which could potentially affect the terrestrial biogeochemical cycles. In addition, our data synthesis suggests that more long-term studies, especially in regions other than temperate ones, are needed for comprehensive assessments of the PNL hypothesis.

  13. Enzymic characterization with progress curve analysis of a collagen peptidase from an enthomopathogenic bacterium, Photorhabdus luminescens.

    Science.gov (United States)

    Marokházi, Judit; Kóczán, György; Hudecz, Ferenc; Gráf, László; Fodor, András; Venekei, István

    2004-05-01

    A proteolytic enzyme, Php-B ( Photorhabdus protease B), was purified from the entomopathogenic bacterium, Photorhabdus luminescens. The enzyme is intracellular, and its molecular mass is 74 kDa. Tested on various peptide and oligopeptide substrates, Php-B hydrolysed only oligopeptides, with significant activity against bradykinin and a 2-furylacryloyl-blocked peptide, Fua-LGPA (2-furylacryloyl-Leu-Gly-Pro-Ala; kcat=3.6x10(2) s(-1), K(m)=5.8x10(-5) M(-1), pH optimum approx. 7.0). The p K(a1) and the p K(a2) values of the enzyme activity (6.1 and 7.9 respectively), as well as experiments with enzyme inhibitors and bivalent metal ions, suggest that the activity of Php-B is dependent on histidine and cysteine residues, but not on serine residues, and that it is a metalloprotease, which most probably uses Zn2+ as a catalytic ion. The enzyme's ability to cleave oligopeptides that contain a sequence similar to collagen repeat (-Pro-Xaa-Gly-), bradykinin and Fua-LGPA (a synthetic substrate for bacterial collagenases and collagen peptidases), but not native collagens (types I and IV) or denatured collagen (gelatin), indicates that Php-B is probably a collagen peptidase, the first enzyme of this type to be identified in an insect pathogen, that might have a role in the nutrition of P. luminescens by degrading small collagen fragments. For the determination of enzyme kinetic constants, we fitted a numerically integrated Michaelis-Menten model to the experimental progress curves. Since this approach has not been used before in the characterization of proteases that are specific for the P1'-P4' substrate sites (e.g. collagenolytic enzymes), we present a comparison of this method with more conventional ones. The results confirm the reliability of the numerical integration method in the kinetic analysis of collagen-peptide-hydrolysing enzymes. PMID:14744262

  14. What Are the Prognostic Factors for Radiographic Progression of Knee Osteoarthritis? A Meta-analysis

    NARCIS (Netherlands)

    A.N. Bastick (Alex); J.N. Belo (Janneke); J. Runhaar (Jos); S.M. Bierma-Zeinstra (Sita)

    2015-01-01

    textabstractBackground: A previous systematic review on prognostic factors for knee osteoarthritis (OA) progression showed associations for generalized OA and hyaluronic acid levels. Knee pain, radiographic severity, sex, quadriceps strength, knee injury, and regular sport activities were not associ

  15. ANSI/ASHRAE/IES Standard 90.1-2010 Final Determination Quantitative Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, Mark A.; Rosenberg, Michael I.; Liu, Bing

    2011-10-31

    The U.S. Department of Energy (DOE) conducted a final quantitative analysis to assess whether buildings constructed according to the requirements of the American National Standards Institute (ANSI)/American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1-2010 (ASHRAE Standard 90.1-2010, Standard 90.1-2010, or 2010 edition) would result in energy savings compared with buildings constructed to ANSI/ASHRAE/IESNA Standard 90.1-2007(ASHRAE Standard 90.1-2007, Standard 90.1-2007, or 2007 edition). The final analysis considered each of the 109 addenda to ASHRAE Standard 90.1-2007 that were included in ASHRAE Standard 90.1-2010. All 109 addenda processed by ASHRAE in the creation of Standard 90.1-2010 from Standard 90.1-2007 were reviewed by DOE, and their combined impact on a suite of 16 building prototype models in 15 ASHRAE climate zones was considered. Most addenda were deemed to have little quantifiable impact on building efficiency for the purpose of DOE's final determination. However, out of the 109 addenda, 34 were preliminarily determined to have a measureable and quantifiable impact. A suite of 240 computer energy simulations for building prototypes complying with ASHRAE 90.1-2007 was developed. These prototypes were then modified in accordance with these 34 addenda to create a second suite of corresponding building simulations reflecting the same buildings compliant with Standard 90.1-2010. The building simulations were conducted using the DOE EnergyPlus building simulation software. The resulting energy use from the complete suite of 480 simulation runs was then converted to energy use intensity (EUI, or energy use per unit floor area) metrics (Site EUI, Primary EUI, and energy cost intensity [ECI]) results for each simulation. For each edition of the standard, these EUIs were then aggregated to a national basis for each prototype using weighting factors based

  16. IVUS-Based FSI Models for Human Coronary Plaque Progression Study: Components, Correlation and Predictive Analysis

    OpenAIRE

    WANG, LIANG; Wu, Zheyang; Yang, Chun; Zheng, Jie; Bach, Richard; Muccigrosso, David; Billiar, Kristen; Maehara, Akiko; Mintz, Gary S; Tang, Dalin

    2014-01-01

    Atherosclerotic plaque progression is believed to be associated with mechanical stress conditions. Patient follow-up in vivo intravascular ultrasound coronary plaque data were acquired to construct fluid-structure interaction (FSI) models with cyclic bending to obtain flow wall shear stress (WSS), plaque wall stress (PWS) and strain (PWSn) data and investigate correlations between plaque progression measured by wall thickness increase (WTI), cap thickness increase (CTI), lipid depth increase ...

  17. Modeling and Predicting AD Progression by Regression Analysis of Sequential Clinical Data

    KAUST Repository

    Xie, Qing

    2016-02-23

    Alzheimer\\'s Disease (AD) is currently attracting much attention in elders\\' care. As the increasing availability of massive clinical diagnosis data, especially the medical images of brain scan, it is highly significant to precisely identify and predict the potential AD\\'s progression based on the knowledge in the diagnosis data. In this paper, we follow a novel sequential learning framework to model the disease progression for AD patients\\' care. Different from the conventional approaches using only initial or static diagnosis data to model the disease progression for different durations, we design a score-involved approach and make use of the sequential diagnosis information in different disease stages to jointly simulate the disease progression. The actual clinical scores are utilized in progress to make the prediction more pertinent and reliable. We examined our approach by extensive experiments on the clinical data provided by the Alzheimer\\'s Disease Neuroimaging Initiative (ADNI). The results indicate that the proposed approach is more effective to simulate and predict the disease progression compared with the existing methods.

  18. Finite Element Analysis of Progressive Failure and Strain Localization of Carbon Fiber/Epoxy Composite Laminates by ABAQUS

    Science.gov (United States)

    Liu, P. F.; Yang, Y. H.; Gu, Z. P.; Zheng, J. Y.

    2015-12-01

    Interaction mechanism between the intralaminar damage and interlaminar delamination of composite laminates is always a challenging issue. It is important to consider the progressive failure and strain softening behaviors simultaneously during the damage modeling and numerical simulation of composites using FEA. This paper performs three-dimensional finite element analysis of the progressive failure and strain localization of composites using FEA. An intralaminar progressive failure model based on the strain components is proposed and the nonlinear cohesive model is used to predict the delamination growth. In particular, the nonlocal integral theory which introduces a length scale into the governing equations is used to regularize the strain localization problems of composite structures. Special finite element codes are developed using ABAQUS to predict the intralaminar and interlaminar damage evolution of composites simultaneously. The carbon fiber/epoxy composite laminates with a central hole demonstrates the developed theoretical models and numerical algorithm by discussing the effects of the mesh sizes and layups patterns. It is shown the strain localization problem can be well solved in the progressive failure analysis of composites when the energy dissipation due to the damage of the fiber, matrix and interface occurs at a relatively wide area.

  19. Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis.

    Directory of Open Access Journals (Sweden)

    Rachael Natrajan

    2016-02-01

    Full Text Available The intra-tumor diversity of cancer cells is under intense investigation; however, little is known about the heterogeneity of the tumor microenvironment that is key to cancer progression and evolution. We aimed to assess the degree of microenvironmental heterogeneity in breast cancer and correlate this with genomic and clinical parameters.We developed a quantitative measure of microenvironmental heterogeneity along three spatial dimensions (3-D in solid tumors, termed the tumor ecosystem diversity index (EDI, using fully automated histology image analysis coupled with statistical measures commonly used in ecology. This measure was compared with disease-specific survival, key mutations, genome-wide copy number, and expression profiling data in a retrospective study of 510 breast cancer patients as a test set and 516 breast cancer patients as an independent validation set. In high-grade (grade 3 breast cancers, we uncovered a striking link between high microenvironmental heterogeneity measured by EDI and a poor prognosis that cannot be explained by tumor size, genomics, or any other data types. However, this association was not observed in low-grade (grade 1 and 2 breast cancers. The prognostic value of EDI was superior to known prognostic factors and was enhanced with the addition of TP53 mutation status (multivariate analysis test set, p = 9 × 10-4, hazard ratio = 1.47, 95% CI 1.17-1.84; validation set, p = 0.0011, hazard ratio = 1.78, 95% CI 1.26-2.52. Integration with genome-wide profiling data identified losses of specific genes on 4p14 and 5q13 that were enriched in grade 3 tumors with high microenvironmental diversity that also substratified patients into poor prognostic groups. Limitations of this study include the number of cell types included in the model, that EDI has prognostic value only in grade 3 tumors, and that our spatial heterogeneity measure was dependent on spatial scale and tumor size.To our knowledge, this is the first

  20. Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology–Genomic Integration Analysis

    Science.gov (United States)

    Natrajan, Rachael; Sailem, Heba; Mardakheh, Faraz K.; Arias Garcia, Mar; Tape, Christopher J.; Dowsett, Mitch; Bakal, Chris; Yuan, Yinyin

    2016-01-01

    Background The intra-tumor diversity of cancer cells is under intense investigation; however, little is known about the heterogeneity of the tumor microenvironment that is key to cancer progression and evolution. We aimed to assess the degree of microenvironmental heterogeneity in breast cancer and correlate this with genomic and clinical parameters. Methods and Findings We developed a quantitative measure of microenvironmental heterogeneity along three spatial dimensions (3-D) in solid tumors, termed the tumor ecosystem diversity index (EDI), using fully automated histology image analysis coupled with statistical measures commonly used in ecology. This measure was compared with disease-specific survival, key mutations, genome-wide copy number, and expression profiling data in a retrospective study of 510 breast cancer patients as a test set and 516 breast cancer patients as an independent validation set. In high-grade (grade 3) breast cancers, we uncovered a striking link between high microenvironmental heterogeneity measured by EDI and a poor prognosis that cannot be explained by tumor size, genomics, or any other data types. However, this association was not observed in low-grade (grade 1 and 2) breast cancers. The prognostic value of EDI was superior to known prognostic factors and was enhanced with the addition of TP53 mutation status (multivariate analysis test set, p = 9 × 10−4, hazard ratio = 1.47, 95% CI 1.17–1.84; validation set, p = 0.0011, hazard ratio = 1.78, 95% CI 1.26–2.52). Integration with genome-wide profiling data identified losses of specific genes on 4p14 and 5q13 that were enriched in grade 3 tumors with high microenvironmental diversity that also substratified patients into poor prognostic groups. Limitations of this study include the number of cell types included in the model, that EDI has prognostic value only in grade 3 tumors, and that our spatial heterogeneity measure was dependent on spatial scale and tumor size. Conclusions To

  1. Selected Area Fishery Evaluation Project Economic Analysis Study Final Report, Final Draft Revision 4: November 10, 2006.

    Energy Technology Data Exchange (ETDEWEB)

    Bonneville Power Administration; Washington Department of Fish and Wildlife; Oregon Department of Fish and Wildlife

    2006-11-01

    The purpose of this Study is to provide an economic review of current and proposed changes to the Select Area Fishery Evaluation Project (SAFE or Project). The Study results are the information requested in comments made on the Project by a joint review dated March 2005 by the Northwest Power and Conservation Council (NPCC) Independent Scientific Review Panel (ISRP) and Independent Economic Analysis Board (IEAB). North et al. (2006) addressed technical questions about operations and plans, and this report contains the response information for comments concerning Project economics. This report can be considered an economic feasibility review meeting guidelines for cost-effective analysis developed by the IEAB (2003). It also contains other economic measurement descriptions to illustrate the economic effects of SAFE. The SAFE is an expansion of a hatchery project (locally called the Clatsop Economic Development Council Fisheries Project or CEDC) started in 1977 that released an early run coho (COH) stock into the Youngs River. The Youngs River entrance to the Columbia River at River Mile 12 is called Youngs Bay, which is located near Astoria, Oregon. The purpose of the hatchery project was to provide increased fishing opportunities for the in-river commercial fishing gillnet fleet. Instead of just releasing fish at the hatchery, a small scale net pen acclimation project in Youngs Bay was tried in 1987. Hirose et al. (1998) found that 1991-1992 COH broodstock over-wintered at the net pens had double the smolt-to-adult return rate (SAR) of traditional hatchery release, less than one percent stray rates, and 99 percent fishery harvests. It was surmised that smolts from other Columbia River hatcheries could be hauled to the net pens for acclimation and release to take advantage of the SAR's and fishing rates. Proposals were tendered to Bonneville Power Administration (BPA) and other agencies to fund the expansion for using other hatcheries smolts and other off

  2. Transuranic-contaminated solid waste Treatment Development Facility. Final safety analysis report

    International Nuclear Information System (INIS)

    The Final Safety Analysis Report (FSAR) for the Transuranic-Contaminated Solid-Waste Treatment Facility has been prepared in compliance with the Department of Energy (DOE) Manual Chapter 0531, Safety of Nonreactor Nuclear Facilities. The Treatment Development Facility (TDF) at the Los Alamos Scientific Laboratory is a research and development facility dedicated to the study of radioactive-waste-management processes. This analysis addresses site assessment, facility design and construction, and the design and operating characteristics of the first study process, controlled air incineration and aqueous scrub off-gas treatment with respect to both normal and accident conditions. The credible accidents having potentially serious consequences relative to the operation of the facility and the first process have been analyzed and the consequences of each postulated credible accident are presented. Descriptions of the control systems, engineered safeguards, and administrative and operational features designed to prevent or mitigate the consequences of such accidents are presented. The essential features of the operating and emergency procedures, environmental protection and monitoring programs, as well as the health and safety, quality assurance, and employee training programs are described

  3. Reactor analysis support package (RASP). Volume 7. PWR set-point methodology. Final report

    International Nuclear Information System (INIS)

    This report provides an overview of the basis and methodology requirements for determining Pressurized Water Reactor (PWR) technical specifications related setpoints and focuses on development of the methodology for a reload core. Additionally, the report documents the implementation and typical methods of analysis used by PWR vendors during the 1970's to develop Protection System Trip Limits (or Limiting Safety System Settings) and Limiting Conditions for Operation. The descriptions of the typical setpoint methodologies are provided for Nuclear Steam Supply Systems as designed and supplied by Babcock and Wilcox, Combustion Engineering, and Westinghouse. The description of the methods of analysis includes the discussion of the computer codes used in the setpoint methodology. Next, the report addresses the treatment of calculational and measurement uncertainties based on the extent to which such information was available for each of the three types of PWR. Finally, the major features of the setpoint methodologies are compared, and the principal effects of each particular methodology on plant operation are summarized for each of the three types of PWR

  4. Transuranic-contaminated solid waste Treatment Development Facility. Final safety analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Warner, C.L. (comp.)

    1979-07-01

    The Final Safety Analysis Report (FSAR) for the Transuranic-Contaminated Solid-Waste Treatment Facility has been prepared in compliance with the Department of Energy (DOE) Manual Chapter 0531, Safety of Nonreactor Nuclear Facilities. The Treatment Development Facility (TDF) at the Los Alamos Scientific Laboratory is a research and development facility dedicated to the study of radioactive-waste-management processes. This analysis addresses site assessment, facility design and construction, and the design and operating characteristics of the first study process, controlled air incineration and aqueous scrub off-gas treatment with respect to both normal and accident conditions. The credible accidents having potentially serious consequences relative to the operation of the facility and the first process have been analyzed and the consequences of each postulated credible accident are presented. Descriptions of the control systems, engineered safeguards, and administrative and operational features designed to prevent or mitigate the consequences of such accidents are presented. The essential features of the operating and emergency procedures, environmental protection and monitoring programs, as well as the health and safety, quality assurance, and employee training programs are described.

  5. Plutonium Finishing Plant (PFP) Final Safety Analysis Report (FSAR) [SEC 1 THRU 11

    Energy Technology Data Exchange (ETDEWEB)

    ULLAH, M K

    2001-02-26

    The Plutonium Finishing Plant (PFP) is located on the US Department of Energy (DOE) Hanford Site in south central Washington State. The DOE Richland Operations (DOE-RL) Project Hanford Management Contract (PHMC) is with Fluor Hanford Inc. (FH). Westinghouse Safety Management Systems (WSMS) provides management support to the PFP facility. Since 1991, the mission of the PFP has changed from plutonium material processing to preparation for decontamination and decommissioning (D and D). The PFP is in transition between its previous mission and the proposed D and D mission. The objective of the transition is to place the facility into a stable state for long-term storage of plutonium materials before final disposition of the facility. Accordingly, this update of the Final Safety Analysis Report (FSAR) reflects the current status of the buildings, equipment, and operations during this transition. The primary product of the PFP was plutonium metal in the form of 2.2-kg, cylindrical ingots called buttoms. Plutonium nitrate was one of several chemical compounds containing plutonium that were produced as an intermediate processing product. Plutonium recovery was performed at the Plutonium Reclamation Facility (PRF) and plutonium conversion (from a nitrate form to a metal form) was performed at the Remote Mechanical C (RMC) Line as the primary processes. Plutonium oxide was also produced at the Remote Mechanical A (RMA) Line. Plutonium processed at the PFP contained both weapons-grade and fuels-grade plutonium materials. The capability existed to process both weapons-grade and fuels-grade material through the PRF and only weapons-grade material through the RMC Line although fuels-grade material was processed through the line before 1984. Amounts of these materials exist in storage throughout the facility in various residual forms left from previous years of operations.

  6. Final report on key comparison CCQM-K100: Analysis of copper in ethanol

    Science.gov (United States)

    Zhou, Tao; Kakoulides, Elias; Zhu, Yanbei; Jaehrling, Reinhard; Rienitz, Olaf; Saxby, David; Phukphatthanachai, Pranee; Yafa, Charun; Labarraque, Guillaume; Cankur, Oktay; Can, Süleyman Z.; Konopelko, Leonid A.; Kustikov, Yu A.; Caciano de Sena, Rodrigo; Marques Rodrigues, Janaina; Fonseca Sarmanho, Gabriel; Fortunato de Carvalho Rocha, Werickson; dos Reis, Lindomar Augusto

    2014-01-01

    The increase in renewable sources in the energy matrix of the countries is an effort to reduce dependency on crude oil and the environmental impacts associated with its use. In order to help overcome the lack of widely accepted quality standards for fuel ethanol and to guarantee its competitiveness in the international trade market, the NMIs have been working to develop certified reference materials for bio-fuels and measurement methods. Inorganic impurities such as Cu, Na and Fe may be present in the fuel ethanol and their presence is associated with corrosion and the formation of oxide deposits in some engine parts. The key comparison CCQM-K100 was carried out under the auspices of the Inorganic Analysis Working Group (IAWG) and the coordination of the National Institute of Metrology, Quality and Technology (INMETRO). The objective of this key comparison was to compare the measurement capabilities of the participants for the determination of Cu in fuel ethanol. Ten NMIs participated in this exercise and most of them used the isotopic dilution method for determining the amount of Cu. The median was chosen as key comparison reference value (KCRV). The assigned KCRV for the Cu content was 0.3589 µg/g with a combined standard uncertainty of 0.0014 µg/g. In general, there is a good agreement among the participants' results. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  7. Fukushima Daiichi Unit 1 Uncertainty Analysis-Exploration of Core Melt Progression Uncertain Parameters-Volume II.

    Energy Technology Data Exchange (ETDEWEB)

    Denman, Matthew R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brooks, Dusty Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    Sandia National Laboratories (SNL) has conducted an uncertainty analysi s (UA) on the Fukushima Daiichi unit (1F1) accident progression wit h the MELCOR code. Volume I of the 1F1 UA discusses the physical modeling details and time history results of the UA. Volume II of the 1F1 UA discusses the statistical viewpoint. The model used was developed for a previous accident reconstruction investigation jointly sponsored by the US Department of Energy (DOE) and Nuclear Regulatory Commission (NRC). The goal of this work was to perform a focused evaluation of uncertainty in core damage progression behavior and its effect on key figures - of - merit (e.g., hydrogen production, fraction of intact fuel, vessel lower head failure) and in doing so assess the applicability of traditional sensitivity analysis techniques .

  8. "Obstacles to School Progression in Rural Pakistan: An Analysis of Gender and Sibling Rivalry Using Field Survey Data"

    OpenAIRE

    Yasuyuki Sawada; Michael Lokshin

    2007-01-01

    This paper aims to identify the obstacles to school progression by integrating field surveys conducted in twenty-five Pakistani villages, using economic theory and econometric analysis. The full-information maximum likelihood (FIML) estimation of the sequential schooling decision model reveals important dynamics of the gender difference in educational attainment, intrahousehold resource-allocation patterns, and transitory income and wealth effects. We find a high educational retention rate an...

  9. Conjoint utility analysis of technical maturity and project progress of construction project

    Directory of Open Access Journals (Sweden)

    Ma Wei

    2016-01-01

    Full Text Available In this paper, taking construction project as the research object, the relationship between the project maturity index calculated by the construction project technical risks with different fine degree and the project progress index is studied, and the equilibrium relationship between the Party A’s utility curve and the Party B’s cost curve of using project maturity index and project progress index as the research variables is analyzed. The results show that, when the construction project technical risk division is more precise, the conjoint utility of the project's technical maturity index and the project progress is higher, and the project’s Party A and Party B two sides are closer to the optimal equilibrium. This shows that the construction project technical risk must be finely divided, and managed and controlled respectively, which will help to improve the conjoint utility of the project Party A and Party B two sides.

  10. Advanced experimental analysis of controls on microbial Fe(III) oxide reduction. First year progress report

    Energy Technology Data Exchange (ETDEWEB)

    Roden, E.E.; Urrutia, M.M.

    1997-07-01

    'The authors have made considerable progress toward a number of project objectives during the first several months of activity on the project. An exhaustive analysis was made of the growth rate and biomass yield (both derived from measurements of cell protein production) of two representative strains of Fe(III)-reducing bacteria (Shewanellaalga strain BrY and Geobactermetallireducens) growing with different forms of Fe(III) as an electron acceptor. These two fundamentally different types of Fe(III)-reducing bacteria (FeRB) showed comparable rates of Fe(III) reduction, cell growth, and biomass yield during reduction of soluble Fe(III)-citrate and solid-phase amorphous hydrous ferric oxide (HFO). Intrinsic growth rates of the two FeRB were strongly influenced by whether a soluble or a solid-phase source of Fe(III) was provided: growth rates on soluble Fe(III) were 10--20 times higher than those on solid-phase Fe(III) oxide. Intrinsic FeRB growth rates were comparable during reduction of HF0 and a synthetic crystalline Fe(III) oxide (goethite). A distinct lag phase for protein production was observed during the first several days of incubation in solid-phase Fe(III) oxide medium, even though Fe(III) reduction proceeded without any lag. No such lag between protein production and Fe(III) reduction was observed during growth with soluble Fe(III). This result suggested that protein synthesis coupled to solid-phase Fe(III) oxide reduction in batch culture requires an initial investment of energy (generated by Fe(III) reduction), which is probably needed for synthesis of materials (e.g. extracellular polysaccharides) required for attachment of the cells to oxide surfaces. This phenomenon may have important implications for modeling the growth of FeRB in subsurface sedimentary environments, where attachment and continued adhesion to solid-phase materials will be required for maintenance of Fe(III) reduction activity. Despite considerable differences in the rate and

  11. Environmental barrier coating (EBC) durability modeling using a progressive failure analysis approach

    Science.gov (United States)

    Abdul-Aziz, Ali; Abumeri, Galib; Troha, William; Bhatt, Ramakrishna T.; Grady, Joseph E.; Zhu, D.

    2012-04-01

    Ceramic matrix composites (CMCs) are getting the attention of most engine manufacturers and aerospace firms for turbine engine and other related applications. This is because of their potential weight advantage and performance benefits. As a protecting guard for these materials, a highly specialized form of environmental barrier coating (EBC) is being developed and explored for high temperature applications that are greater than 1100 °C1,2. The EBCs are typically a multilayer of coatings and are on the order of hundreds of microns thick. CMCs are generally porous materials and this feature is somewhat beneficial since it allows some desirable infiltration of the EBC. Their degradation usually includes coating interface oxidation as opposed to moisture induced matrix degradation which is generally seen at a higher temperature. A variety of factors such as residual stresses, coating process related flaws, and casting conditions may influence the strength of degradation. The cause of such defects which cause cracking and other damage is that not much energy is absorbed during fracture of these materials. Therefore, an understanding of the issues that control crack deflection and propagation along interfaces is needed to maximize the energy dissipation capabilities of layered ceramics. Thus, evaluating components and subcomponents made out of CMCs under gas turbine engine conditions is suggested to demonstrate that these material will perform as expected and required under these aggressive environmental circumstances. Progressive failure analysis (PFA) is applied to assess the damage growth of the coating under combined thermal and mechanical loading conditions. The PFA evaluation is carried out using a full-scale finite element model to account for the average material failure at the microscopic or macroscopic levels. The PFA life prediction evaluation identified the root cause for damage initiation and propagation. It indicated that delamination type damage

  12. Development of a Progressive Failure Finite Element Analysis For a Braided Composite Fuselage Frame

    OpenAIRE

    Hart, Daniel Constantine

    2002-01-01

    Short, J-section columns fabricated from a textile composite are tested in axial compression to study the modes of failure with and without local buckling occuring.The textile preform architecture is a 2x2, 2-D triaxial braid with a yarn layup of [0 deg 18k/+-64 deg 6k] 39.7% axial. The preform was resin transfer molded with 3M PR500 epoxy resin. Finite element analyses (FEA) of the test specimens are conducted to assess intra- and inter- laminar progressive failure models. These progressive...

  13. Progression of biopsy-measured liver fibrosis in untreated patients with hepatitis C infection: non-Markov multistate model analysis.

    Directory of Open Access Journals (Sweden)

    Peter Bacchetti

    Full Text Available BACKGROUND: Fibrosis stages from liver biopsies reflect liver damage from hepatitis C infection, but analysis is challenging due to their ordered but non-numeric nature, infrequent measurement, misclassification, and unknown infection times. METHODS: We used a non-Markov multistate model, accounting for misclassification, with multiple imputation of unknown infection times, applied to 1062 participants of whom 159 had multiple biopsies. Odds ratios (OR quantified the estimated effects of covariates on progression risk at any given time. RESULTS: Models estimated that progression risk decreased the more time participants had already spent in the current stage, African American race was protective (OR 0.75, 95% confidence interval 0.60 to 0.95, p = 0.018, and older current age increased risk (OR 1.33 per decade, 95% confidence interval 1.15 to 1.54, p = 0.0002. When controlled for current age, older age at infection did not appear to increase risk (OR 0.92 per decade, 95% confidence interval 0.47 to 1.79, p = 0.80. There was a suggestion that co-infection with human immunodeficiency virus increased risk of progression in the era of highly active antiretroviral treatment beginning in 1996 (OR 2.1, 95% confidence interval 0.97 to 4.4, p = 0.059. Other examined risk factors may influence progression risk, but evidence for or against this was weak due to wide confidence intervals. The main results were essentially unchanged using different assumed misclassification rates or imputation of age of infection. DISCUSSION: The analysis avoided problems inherent in simpler methods, supported the previously suspected protective effect of African American race, and suggested that current age rather than age of infection increases risk. Decreasing risk of progression with longer time already spent in a stage was also previously found for post-transplant progression. This could reflect varying disease activity, with recent progression indicating

  14. Engineering Evaluation/Cost Analysis for Power Burst Facility (PER-620) Final End State and PBF Vessel Disposal

    International Nuclear Information System (INIS)

    Preparation of this engineering evaluation/cost analysis is consistent with the joint U.S. Department of Energy and U.S. Environmental Protection Agency Policy on Decommissioning of Department of Energy Facilities Under the Comprehensive Environmental Response, Compensation, and Liability Act, (DOE and EPA 1995) which establishes the Comprehensive Environmental, Response, Compensation, and Liability Act non-time critical removal action process as an approach for decommissioning. The scope of this engineering evaluation/cost analysis is to evaluate alternatives and recommend a preferred alternative for the final end state of the PBF and the final disposal location for the PBF vessel

  15. Engineering Evaluation/Cost Analysis for Power Burst Facility (PER-620) Final End State and PBF Vessel Disposal

    Energy Technology Data Exchange (ETDEWEB)

    B. C. Culp

    2007-05-01

    Preparation of this engineering evaluation/cost analysis is consistent with the joint U.S. Department of Energy and U.S. Environmental Protection Agency Policy on Decommissioning of Department of Energy Facilities Under the Comprehensive Environmental Response, Compensation, and Liability Act, (DOE and EPA 1995) which establishes the Comprehensive Environmental, Response, Compensation, and Liability Act non-time critical removal action process as an approach for decommissioning. The scope of this engineering evaluation/cost analysis is to evaluate alternatives and recommend a preferred alternative for the final end state of the PBF and the final disposal location for the PBF vessel.

  16. A progress report on detector and analysis development for the Hbar-HFS experiment within the ASACUSA collaboration

    International Nuclear Information System (INIS)

    Full text: Charge, Parity and Time (CPT) symmetry is the most fundamental theoretical concepts in particle physics. The ASACUSA-Hbar collaboration aims to test this property by measuring the hyperfine structure in ground state antihydrogen. Due to the big challenge in producing an antihydrogen beam the main background for this measurement are cosmics. To discriminate against cosmic rays we need a sophisticated analysis system together with a tracking detector for pions. In this talk I will report the progress in detector and analysis development during the long CERN shutdown and give an outlook on the planned activities until the beam time 2014 starts. (author)

  17. Chimera-free, high copy number YAC libraries and efficient methods of analysis. Final technical progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The first experiment involved a low chimera YAC library in recombination deficient host strains. To determine if the genetic background of the yeast host strain contributes to the formation of chimeric YACs the same YAC ligation mixture was introduced into three isogenic yeast hosts differing only in their recombination abilities. To prepare YACs, human genomic DNA was partially digested with EcoR1 and then ligated to YAC vector pCGS966 arms. DNA was size fractionated before and after ligation by preparative pulsed field gel electrophoresis (CHEF), selecting for fragments greater than 400 kb, and introduced into competent spheroplasts. CHEF gel Southern blots of resulting colony-purified YACs were probed with human DNA to determine if multiple YACs or YAC fragments were present in the same cell. The frequency of chimeric YACs was measured by fluorescence in situ hybridization (FISH) of YACs to human prometaphase spreads. YACs that hybridized to more than one location were assumed to be chimeric. In the second experiment new YAC vectors featuring tags for capture of YACs and YAC inserts were constructed. Yeast Artificial Chromosomes (YACs) have been of tremendous value in the physical mapping of the human genome. Because they can carry very large inserts, YACs are likely not only to contain entire genes but also their control elements. However, the only mode of purification of YAC DNA from current commonly used YAC libraries such as the CEPH library is by pulsed field gel electrophoresis. This is an inefficient, time consuming process and due to the single copy nature of these YACs, often result in poor yields. The vector pCGS1000 was designed to test new efficient ways of YAC DNA purification.

  18. Item and Error Analysis on Raven's Coloured Progressive Matrices in Williams Syndrome

    Science.gov (United States)

    Van Herwegen, Jo; Farran, Emily; Annaz, Dagmara

    2011-01-01

    Raven's Coloured Progressive Matrices (RCPM) is a standardised test that is commonly used to obtain a non-verbal reasoning score for children. As the RCPM involves the matching of a target to a pattern it is also considered to be a visuo-spatial perception task. RCPM is therefore frequently used in studies in Williams Syndrome (WS), in order to…

  19. Experimental verification of a progressive damage model for composite laminates based on continuum damage mechanics. M.S. Thesis Final Report

    Science.gov (United States)

    Coats, Timothy William

    1994-01-01

    Progressive failure is a crucial concern when using laminated composites in structural design. Therefore the ability to model damage and predict the life of laminated composites is vital. The purpose of this research was to experimentally verify the application of the continuum damage model, a progressive failure theory utilizing continuum damage mechanics, to a toughened material system. Damage due to tension-tension fatigue was documented for the IM7/5260 composite laminates. Crack density and delamination surface area were used to calculate matrix cracking and delamination internal state variables, respectively, to predict stiffness loss. A damage dependent finite element code qualitatively predicted trends in transverse matrix cracking, axial splits and local stress-strain distributions for notched quasi-isotropic laminates. The predictions were similar to the experimental data and it was concluded that the continuum damage model provided a good prediction of stiffness loss while qualitatively predicting damage growth in notched laminates.

  20. Failure Progress of 3D Reinforced GFRP Laminate during Static Bending, Evaluated by Means of Acoustic Emission and Vibrations Analysis

    Directory of Open Access Journals (Sweden)

    Mateusz Koziol

    2015-12-01

    Full Text Available The work aimed to assess the failure progress in a glass fiber-reinforced polymer laminate with a 3D-woven and (as a comparison plain-woven reinforcement, during static bending, using acoustic emission signals. The innovative method of the separation of the signal coming from the fiber fracture and the one coming from the matrix fracture with the use of the acoustic event’s energy as a criterion was applied. The failure progress during static bending was alternatively analyzed by evaluation of the vibration signal. It gave a possibility to validate the results of the acoustic emission. Acoustic emission, as well as vibration signal analysis proved to be good and effective tools for the registration of failure effects in composite laminates. Vibration analysis is more complicated methodologically, yet it is more precise. The failure progress of the 3D laminate is “safer” and more beneficial than that of the plain-woven laminate. It exhibits less rapid load capacity drops and a higher fiber effort contribution at the moment of the main laminate failure.

  1. Mutational analysis of root characters in food plants. Proceedings of a final research coordination meeting

    International Nuclear Information System (INIS)

    genomics and proteomics to address important agricultural issues, supporting successful agricultural production with minimal impact on the environment. Improvements in screening techniques and development of molecular markers are ways to alleviate the need for direct root assessment and speed up selection in plant breeding programmes. Root architecture models provide a tool to address the space-time dynamics of the soil/plant system. Genetic analysis of quantitative traits and methods in forward and reverse genetics will also contribute to breeding crops with root systems suitable for a range of agricultural environments. Recent evidence indicates that plant stresses are mediated by changes at the root system level. In this context, mutants and mutational analysis of root characters are becoming significant elements in research that seeks to clarify the ways by which root structure and function respond to environmental cues and alleviate the impact of stress. This publication summarizes the results presented at the third and final Research Coordination meeting (RCM) of the CRP, which was held in Antalya, Turkey, 11-15 October 2004

  2. Evaluation of safety assessment methodologies in Rocky Flats Risk Assessment Guide (1985) and Building 707 Final Safety Analysis Report (1987)

    International Nuclear Information System (INIS)

    FSARs. Rockwell International, as operating contractor at the Rocky Flats plant, conducted a safety analysis program during the 1980s. That effort resulted in Final Safety Analysis Reports (FSARs) for several buildings, one of them being the Building 707 Final Safety Analysis Report, June 87 (707FSAR) and a Plant Safety Analysis Report. Rocky Flats Risk Assessment Guide, March 1985 (RFRAG85) documents the methodologies that were used for those FSARs. Resources available for preparation of those Rocky Flats FSARs were very limited. After addressing the more pressing safety issues, some of which are described below, the present contractor (EG ampersand G) intends to conduct a program of upgrading the FSARs. This report presents the results of a review of the methodologies described in RFRAG85 and 707FSAR and contains suggestions that might be incorporated into the methodology for the FSAR upgrade effort

  3. Analysis of the utilization history and the planning and the participation profiles of the shaft plant Asse II. Final report

    International Nuclear Information System (INIS)

    The report on the utilization history of Asse II covers the following issues: Historical facts of the purchase of the shaft plant Asse II, decision sequences and line of arguments, research mine or final repository? Emplacement of radioactive materials (inventory), stability of the mine layout and water ingress, risk assessment - accident analysis, communication and public information, conclusions and recommendations.

  4. Geother evaluation and improvement: A progress report including test cases for two-dimensional BWIP (Basalt Waste Isolation Project) analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bian, S.H.; Budden, M.J.; Bartley, C.L.; Yung, S.C.

    1988-03-01

    The objective of the work is to evaluate the GEOTHER code and peform necessary improvements to make it specifically suitable for predicting the environmental conditions of the waste package for the Basalt Waste Isolation Project (BWIP); and to perform resaturation analyses, that is, the analyses of steam formation and condensation, for the repository and waste package using the improved GEOTHER code. This is a progress report to BWIP documenting the status of GEOTHER code testing, evaluation, and improvements. The computational results documented in this report reflect the current condition of the code and the condition before code improvements. The test cases used are intended for examining the code features in sufficient detail and are not intended to be taken as final conclusions for BWIP applications.

  5. CGE Simulation Analysis on the Labor Transfer, Agricultural Technical Progress, and Economic Development in Chongqing

    OpenAIRE

    Heng Wang; Maosheng Ran

    2014-01-01

    The basic structure of a CGE model dividing Mainland China into two parts, including Chongqing and rest regions, is described. Based on this CGE model, both the unilateral impact and collaborative impact of two policies, agricultural technical progress and supporting policies for improving rural labor transfer on the economic development in Chongqing, are simulated and analyzed. The results demonstrate that compared with the sum of each unilateral policy effect, the collaboration of two polic...

  6. Poro Hypo Plastic analysis of the progressive excavation of the Mol URL connecting Gallery

    OpenAIRE

    Desrues, Jacques; Bésuelle, Pierre; Coll, Cécile; Collin, Frédéric; Li, Xiang Ling

    2006-01-01

    In the framework of a Euratom research program devoted to Nuclear Waste deposition security assessment, a numerical simulation of the excavation of a gallery in the Boom Clay layer at Mol (Belgium) has been performed In order to model the progressive excavation and lining installation process, a special sequence of desactivation/activation of sets of elements was elaborated. In particular, this numerical strategy allowed to take into account the fact that, due to the deformation of the mas...

  7. Progress in the analysis of selenium x-ray laser targets

    Energy Technology Data Exchange (ETDEWEB)

    Rosen, M.D.; Hagelstein, P.L.

    1986-03-01

    We review progress in the modeling of Ne-like-Se XRLs. Dielectronic recombination plays an important role in the level kinetics as well as in ionization balance. Refraction becomes important at target lengths greater than 2 cm by reducing signal at 0/sup 0/ view, and by having much larger signals emitted at a 10 to 20 mrad view. We predict success in scaling these systems to lower lambda with higher Z targets, but at great cost in required driver power.

  8. Progress in the analysis of selenium x-ray laser targets

    International Nuclear Information System (INIS)

    We review progress in the modeling of Ne-like-Se XRLs. Dielectronic recombination plays an important role in the level kinetics as well as in ionization balance. Refraction becomes important at target lengths greater than 2 cm by reducing signal at 00 view, and by having much larger signals emitted at a 10 to 20 mrad view. We predict success in scaling these systems to lower lambda with higher Z targets, but at great cost in required driver power

  9. Progressive collapse analysis of four existing reinforced concrete buildings using linear procedure

    OpenAIRE

    Shams Al, Ahmed Zaid

    2012-01-01

    ABSTRACT: Progressive collapse occurs when local failure in a structural element spreads to the adjoining members, this might promote additional failure. The damage will propagate till the structure reaches to new static equilibrium configuration. Otherwise, entire collapse will happen. On the other hand, local damage in the structural system will be arrested if the facility has an adequate design to bridge over the damage and redistribute the loads. In general, buildings are designed ...

  10. An analysis on the severe accident progression with operator recovery actions

    International Nuclear Information System (INIS)

    Highlights: • Severe accident progression for the station blackout and SBLOCA accident. • Analyses on APR1400 using MELCOR. • Operator recovery actions for decay heat removal and inventory make up. • Determine the time allowed for the operator to prevent reactor vessel failure. • Insight for the operator recovery actions for the severe accident management. - Abstract: Analyses on the severe accident progressions for the station blackout (SBO) accident and small break LOCA (SBLOCA) initiated severe accident were performed for APR1400 by using MELCOR computer code. Operator recovery actions for decay heat removal and inventory make up using a depressurization system and safety injection pump were simulated in parallel with a simulation of the severe accident progression. Sensitivity studies on the operator actions were performed to investigate the changes in the timing of the reactor vessel failure and to determine the time allowed for the operator to prevent reactor vessel failure. Sensitivity analyses on the effect of major modeling parameters were performed additionally to quantify the uncertainties in timing. It is found that the operator has about 2 h for the recovery actions after the indication of core damage by the signal of core exit thermocouple (CET) for the SBLOCA initiated severe accident, while the operator has to take immediate actions after the indication of core damage by CET for the SBO accident

  11. Intralaminar and Interlaminar Progressive Failure Analysis of Composite Panels with Circular Cutouts

    Science.gov (United States)

    Goyal, Vinay K.; Jaunky, Navin; Johnson, Eric R.; Ambur, Damodar

    2002-01-01

    A progressive failure methodology is developed and demonstrated to simulate the initiation and material degradation of a laminated panel due to intralaminar and interlaminar failures. Initiation of intralaminar failure can be by a matrix-cracking mode, a fiber-matrix shear mode, and a fiber failure mode. Subsequent material degradation is modeled using damage parameters for each mode to selectively reduce lamina material properties. The interlaminar failure mechanism such as delamination is simulated by positioning interface elements between adjacent sublaminates. A nonlinear constitutive law is postulated for the interface element that accounts for a multi-axial stress criteria to detect the initiation of delamination, a mixed-mode fracture criteria for delamination progression, and a damage parameter to prevent restoration of a previous cohesive state. The methodology is validated using experimental data available in the literature on the response and failure of quasi-isotropic panels with centrally located circular cutouts loaded into the postbuckling regime. Very good agreement between the progressive failure analyses and the experimental results is achieved if the failure analyses includes the interaction of intralaminar and interlaminar failures.

  12. Modeling, analysis and experiments for fusion nuclear technology: FNT progress report: Modeling and FINESSE

    International Nuclear Information System (INIS)

    This document is a progress report on two technical studies carried out during 1986, both of which relate to the implementation phase of FNT. The first, which is a follow-up to FINESSE, focuses on specific key questions for: (1) very near-term (0 to 3 years) non-fusion experiments and facilities, and (2) FNT testing in a fusion facility. The second is the initial stage of a detailed effort to develop theory, models and computer codes for predicting the performance of nuclear components. Chapters are presented on (1) introduction and chapter summaries, (2) non-fusion experiments and facilities, (3) fusion testing issues, and (4) theory and modeling. Chapter 2 is an assessment of the relative advantages of many solid breeders, neutron multipliers and configurations. Various issues affecting design and cost of the blanket are examined in Chapter 3. Chapter 4 reports on the progress of the initial stage of an effort to develop theory and analytical and numerical models for nuclear components. A major part of the effort has focused on modeling of MHD effects for liquid metal blankets. Progress has also been made on modeling tritium transport and inventory in solid breeder blankets and the thermomechanical behavior of liquid-metal-cooled limiters

  13. Integrated Data Collection Analysis (IDCA) Program - Final Review September 12, 2012 at DHS

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Phillips, Jason J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shelley, Timothy J. [Air Force Research Lab. (AFRL), Tyndall AFB, FL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2012-11-26

    The Integrated Data Collection Analysis (IDCA) program conducted a final program review at the Department of Homeland Security on September 12, 2012. The review was focused on the results of the program over the complete performance period. A summary presentation delineating the accomplished tasks started the meeting, followed by technical presentations on various issues that arose during the performance period. The presentations were completed with a statistical evaluation of the testing results from all the participants in the IDCA Proficiency Test study. The meeting closed with a discussion of potential sources of funding for continuing work to resolve some of these technical issues. This effort, funded by the Department of Homeland Security (DHS), put the issues of safe handling of these materials in perspective with standard military explosives. The study added Small-Scale Safety and Thermal (SSST) testing results for a broad suite of different HMEs to the literature, and suggested new guidelines and methods to develop safe handling practices for HMEs. Each participating testing laboratory used identical test materials and preparation methods wherever possible. Note, however, the test procedures differ among the laboratories. The results were compared among the laboratories and then compared to historical data from various sources. The testing performers involved were Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Naval Surface Warfare Center, Indian Head Division (NSWC IHD), Sandia National Laboratories (SNL), and Air Force Research Laboratory, Tyndall AFB (AFRL/RXQL). These tests were conducted as a proficiency study in order to establish some consistency in test protocols, procedures, and experiments and to compare results when these testing variables cannot be made consistent.

  14. Annex D-200 Area Interim Storage Area Final Safety Analysis Report [FSAR] [Section 1 & 2

    Energy Technology Data Exchange (ETDEWEB)

    CARRELL, R D

    2002-07-16

    The 200 Area Interim Storage Area (200 Area ISA) at the Hanford Site provides for the interim storage of non-defense reactor spent nuclear fuel (SNF) housed in aboveground dry cask storage systems. The 200 Area ISA is a relatively simple facility consisting of a boundary fence with gates, perimeter lighting, and concrete and gravel pads on which to place the dry storage casks. The fence supports safeguards and security and establishes a radiation protection buffer zone. The 200 Area ISA is nominally 200,000 ft{sup 2} and is located west of the Canister Storage Building (CSB). Interim storage at the 200 Area ISA is intended for a period of up to 40 years until the materials are shipped off-site to a disposal facility. This Final Safety Analysis Report (FSAR) does not address removal from storage or shipment from the 200 Area ISA. Three different SNF types contained in three different dry cask storage systems are to be stored at the 200 Area ISA, as follows: (1) Fast Flux Test Facility Fuel--Fifty-three interim storage casks (ISC), each holding a core component container (CCC), will be used to store the Fast Flux Test Facility (FFTF) SNF currently in the 400 Area. (2) Neutron Radiography Facility (NRF) TRIGA'--One Rad-Vault' container will store two DOT-6M3 containers and six NRF TRIGA casks currently stored in the 400 Area. (3) Commercial Light Water Reactor Fuel--Six International Standards Organization (ISO) containers, each holding a NAC-I cask4 with an inner commercial light water reactor (LWR) canister, will be used for commercial LWR SNF from the 300 Area. An aboveground dry cask storage location is necessary for the spent fuel because the current storage facilities are being shut down and deactivated. The spent fuel is being transferred to interim storage because there is no permanent repository storage currently available.

  15. 3-D nuclear analysis of the final optics of a laser driven fusion power plant

    International Nuclear Information System (INIS)

    In the High Average Power Laser (HAPL) program, power plant designs are assessed with 350 MJ yield targets driven by 40 KrF laser beams. The final optics system that focuses the laser onto the target includes a grazing incidence metallic mirror (GIMM) located at 24 m from the target with 85 angle of incidence. The GIMM is in direct line of sight of the target and has a 50 microns thick aluminum coating. Several options were considered for the substrate material. We performed three-dimensional (3-D) neutronics calculations to assess the impact of the GIMM design options on the nuclear environment at the dielectric focusing and turning mirrors. We used the recently developed MCNPX-CGM Monte Carlo code that allows performing the neutronics calculations directly in the exact CAD model. The most recent continuous energy fusion evaluated nuclear data library (FENDL-2.1) was used. One of the 40 beamlines was modeled with surrounding reflective boundaries. We considered beam duct configuration modifications such as utilizing neutron traps behind the mirrors to reduce radiation streaming. Several variance reduction techniques were utilized to reduce the statistical uncertainties. The results indicate that material choice and thickness for the GIMM impact the nuclear environment at all mirrors. The neutron flux and nuclear heating at the dielectric mirrors are a factor of ∝1.6 higher when AlBeMet is used instead of SiC as substrate in the GIMM. The fast neutron flux decreases by about two orders of magnitude as one moves from the GIMM to the focusing mirror with an additional two orders of magnitude attenuation at the turning mirror accompanied with significant spectrum softening. In this paper, the details of the analysis and results will be presented and the expected optics lifetime will be assessed. (orig.)

  16. National Research Council Dialogue to Assess Progress on NASA's Systems Engineering Cost/Risk Analysis Capability Roadmap Development: General Background and Introduction

    Science.gov (United States)

    Regenie, Victoria

    2005-01-01

    Contents include the following: General Background and Introduction of Capability. Roadmaps for Systems Engineering Cost/Risk Analysis. Agency Objectives. Strategic Planning Transformation. Review Capability Roadmaps and Schedule. Review Purpose of NRC Review. Capability Roadmap Development (Progress to Date).

  17. Mastoidectomy performance assessment of virtual simulation training using final-product analysis

    DEFF Research Database (Denmark)

    Andersen, Steven A W; Cayé-Thomasen, Per; Sørensen, Mads S

    2015-01-01

    OBJECTIVES/HYPOTHESIS: The future development of integrated automatic assessment in temporal bone virtual surgical simulators calls for validation against currently established assessment tools. This study aimed to explore the relationship between mastoidectomy final-product performance assessmen...

  18. Initial Northwest Power Act Power Sales Contracts : Final Environmental Impact Statement. Volume 1, Environmental Analysis.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-01-01

    This is volume 1 of the final environmental impact statement of the Bonneville Power Administration Information is included on the following: Purpose of and need for action; alternatives including the proposed action; affected environment; and environmental consequences.

  19. Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Daizong Wen

    2015-01-01

    Full Text Available Background. To evaluate the efficacy and acceptability of orthokeratology for slowing myopic progression in children with a well conducted evidence-based analysis. Design. Meta-analysis. Participants. Children from previously reported comparative studies were treated by orthokeratology versus control. Methods. A systematic literature retrieval was conducted in MEDLINE, EMBASE, Cochrane Library, World Health Organization International Clinical Trials Registry Platform, and ClinicalTrials.gov. The included studies were subjected to meta-analysis using Stata version 10.1. Main Outcome Measures. Axial length change (efficacy and dropout rates (acceptability during 2-year follow-up. Results. Eight studies involving 769 subjects were included. At 2-year follow-up, a statistically significant difference was observed in axial length change between the orthokeratology and control groups, with a weighted mean difference (WMD of −0.25 mm (95% CI, −0.30 to −0.21. The pooled myopic control rate declined with time, with 55, 51, 51, and 41% obtained after 6, 12, 18, and 24 months of treatment, respectively. No statistically significant difference was obtained for dropout rates between the orthokeratology and control groups at 2-year follow-up (OR, 0.79; 95% CI, 0.52 to 1.22. Conclusions. Orthokeratology is effective and acceptable for slowing myopic progression in children with careful education and monitoring.

  20. How accurate are interpretations of curriculum-based measurement progress monitoring data? Visual analysis versus decision rules.

    Science.gov (United States)

    Van Norman, Ethan R; Christ, Theodore J

    2016-10-01

    Curriculum based measurement of oral reading (CBM-R) is used to monitor the effects of academic interventions for individual students. Decisions to continue, modify, or terminate these interventions are made by interpreting time series CBM-R data. Such interpretation is founded upon visual analysis or the application of decision rules. The purpose of this study was to compare the accuracy of visual analysis and decision rules. Visual analysts interpreted 108 CBM-R progress monitoring graphs one of three ways: (a) without graphic aids, (b) with a goal line, or (c) with a goal line and a trend line. Graphs differed along three dimensions, including trend magnitude, variability of observations, and duration of data collection. Automated trend line and data point decision rules were also applied to each graph. Inferential analyses permitted the estimation of the probability of a correct decision (i.e., the student is improving - continue the intervention, or the student is not improving - discontinue the intervention) for each evaluation method as a function of trend magnitude, variability of observations, and duration of data collection. All evaluation methods performed better when students made adequate progress. Visual analysis and decision rules performed similarly when observations were less variable. Results suggest that educators should collect data for more than six weeks, take steps to control measurement error, and visually analyze graphs when data are variable. Implications for practice and research are discussed. PMID:27586069

  1. An analysis of the Spanish electrical utility industry. Economies of scale, technological progress and efficiency

    International Nuclear Information System (INIS)

    In this paper we propose a model to explain the behaviour of the Spanish electrical utility industry during the period 1987-1997, under the then existing regulatory system (Marco Legal Estable). The paper will study the presence of economies of scale, the effect of technological progress and the differences in the efficiency of the different companies within the market. The paper concludes that the Spanish electrical utility industry was not, in fact, characterized by economies of scale during this period, but witnessed a great improvement in efficiency within that period. All the critical market factors remind stable. (author)

  2. Stochastic Unit Commitment via Progressive Hedging - Extensive Analysis of Solution Methods

    DEFF Research Database (Denmark)

    Ordoudis, Christos; Pinson, Pierre; Zugno, Marco;

    2015-01-01

    Owing to the massive deployment of renewable power production units over the last couple of decades, the use of stochastic optimization methods to solve the unit commitment problem has gained increasing attention. Solving stochastic unit commitment problems in large-scale power systems requires...... high computational power, as stochastic models are dramatically more complex than their deterministic counterparts. This paper provides new insight into the potential of Progressive Hedging to decrease the solution time of the stochastic unit commitment problem with a relatively small trade-off in...

  3. Depression and disease progression in amyotrophic lateral sclerosis: A comprehensive meta-regression analysis.

    Science.gov (United States)

    Pagnini, Francesco; Manzoni, Gian Mauro; Tagliaferri, Aurora; Gibbons, Chris J

    2015-08-01

    Depression in people with amyotrophic lateral sclerosis, a fatal and progressive neurodegenerative disorder, is a serious issue with important clinical consequences. However, physical impairment may confound the diagnosis when using generic questionnaires. We conducted a comprehensive review of literature. Mean scores from depression questionnaires were meta-regressed on study-level mean time since onset of symptoms. Data from 103 studies (3190 subjects) indicate that the Beck Depression Inventory and, to a lesser degree, the Hospital Anxiety and Depression Scale are influenced by the time since symptom onset, strongly related to physical impairment. Our results suggest that widely used depression scales overestimate depression due to confounding with physical symptoms. PMID:24764286

  4. An analysis of the educational progress of children with special educational needs

    OpenAIRE

    Claire Crawford; Anna Vignoles

    2010-01-01

    One in five children in England are recorded as having some kind of special educational need, meaning that they receive additional help in school; yet there is very little evidence of the effect of such assistance on pupil’s academic progress. This is at least partly because it is usually very difficult to define an appropriate control group for pupils with special educational needs. To overcome this issue, we make use of extremely rich data from the Avon Longitudinal Study of Parents and C...

  5. CGE simulation analysis on the labor transfer, agricultural technical progress, and economic development in Chongqing.

    Science.gov (United States)

    Wang, Heng; Ran, Maosheng

    2014-01-01

    The basic structure of a CGE model dividing Mainland China into two parts, including Chongqing and rest regions, is described. Based on this CGE model, both the unilateral impact and collaborative impact of two policies, agricultural technical progress and supporting policies for improving rural labor transfer on the economic development in Chongqing, are simulated and analyzed. The results demonstrate that compared with the sum of each unilateral policy effect, the collaboration of two policies has more effective impact on facilitating the labor transfer, promoting regional economic growth, and improving income and welfare of urban and rural residents. PMID:24892037

  6. Progress on 129I analysis and its application in environmental and geological researches

    DEFF Research Database (Denmark)

    Fan, Yukun; Hou, Xiaolin; Zhou, Weijian

    2013-01-01

    environmental level. Based on its source terms, chemical properties and environmental behaviors, 129Ican be applied for geological dating in a range of 2–80Ma, investigation of formation and migration of hydrocarbon, circulation of ocean water, atmospheric process of iodine, as well as reconstruction of...... interferences, as well as preparation of suitable target for AMS measurement. The major applications in environmental and geological researches are reviewed, which mainly focus on the new progress and potential development in the future. The application of 129I in the investigation of radioactive contamination...

  7. Experimental investigations and seismic analysis for benchmark study of 1000 MW WWER type units (water-cooled and moderated reactor) nuclear power plant Kozloduy. Final report from 1 November 1994 - 31 October 1995

    International Nuclear Information System (INIS)

    This final report summarizes the research carried out and the results obtained presented in previous progress reports. In includes the description of the research carried out, namely, definition of terms and references, criteria, design parameters and methods of analysis; development of 3-dimensional and 2-dimensional mathematical models for diesel generator stations concerning seismic analyses; supports and anchorages analyses and seismic capacity estimation for main components of the cooling system; methodology for verification of component anchorages; conclusions drawn concerning the seismic safety of Kozloduy NPP

  8. Final repository design and optimization. Report on work package 6. Preliminary safety analysis for the site Gorleben

    International Nuclear Information System (INIS)

    The report on the preliminary safety analysis of the final repository Gorleben contains the following chapters: (1) Introduction and aim of the task. (2) Fundamentals and boundary conditions: Frame of radioactive wastes; waste package geometries and masses; geology; basic radiological data; basic thermal data; basic mechanical data, borderlines to the planning fundamentals in AP5. (3) Final repository design and optimization: design requirements; final repository concepts; mine layout; estimated time schedule. (4) Optimization possibilities: Optimization targets; optimization possibilities; operational safety; human intrusion. (5) Demonstration of subcriticality: computational methods and modeling assumptions; spent LWR fuels: spent fuels from test and prototype nuclear power plants and research reactors; assessment. (6) Summary of identified required fuel element work.

  9. In vitro root caries progression measured by 125I absorptiometry: comparison with chemical analysis

    International Nuclear Information System (INIS)

    Radiation from a 125I source and a non-image-forming detector was used for non-destructive measurements of root caries progression. Blocks were cut parallel to the cementum surface of unexposed human roots. These blocks were then individually demineralized in under-saturated calcium phosphate solutions over an 84-hour period. In order for the in vitro root surface demineralization to be followed, the changes in transmission (delta T) through the blocks were measured, by 125I absorptiometry, eight times during the course of the experiment. Chemical analyses of the calcium output (delta Ca) from the blocks into the demineralizing solutions were also performed, and the rate of demineralization (Vdem) was calculated from these values. The precision of 125I absorptiometry was calculated from 176 duplicate transmission measurements, and the coefficient of variation was found to be 0.20%. The correlation coefficient between delta T and total delta Ca for each of 22 cementum/dentin blocks ranged between r = 0.934 and r = 0.998. The progression of root hard-tissue lesions observed by these two methods and by the calculated Vdem was found to be proportional to the square and cubic roots of time. The study shows that 125I absorptiometry can be used for continuous non-destructive measurements of root hard-tissue demineralization in vitro

  10. In vitro root caries progression measured by /sup 125/I absorptiometry: comparison with chemical analysis

    Energy Technology Data Exchange (ETDEWEB)

    Almqvist, H.; Wefel, J.S.; Lagerloef, F.E.; Ekstrand, J.; Henrikson, C.O.

    1988-09-01

    Radiation from a /sup 125/I source and a non-image-forming detector was used for non-destructive measurements of root caries progression. Blocks were cut parallel to the cementum surface of unexposed human roots. These blocks were then individually demineralized in under-saturated calcium phosphate solutions over an 84-hour period. In order for the in vitro root surface demineralization to be followed, the changes in transmission (delta T) through the blocks were measured, by /sup 125/I absorptiometry, eight times during the course of the experiment. Chemical analyses of the calcium output (delta Ca) from the blocks into the demineralizing solutions were also performed, and the rate of demineralization (Vdem) was calculated from these values. The precision of /sup 125/I absorptiometry was calculated from 176 duplicate transmission measurements, and the coefficient of variation was found to be 0.20%. The correlation coefficient between delta T and total delta Ca for each of 22 cementum/dentin blocks ranged between r = 0.934 and r = 0.998. The progression of root hard-tissue lesions observed by these two methods and by the calculated Vdem was found to be proportional to the square and cubic roots of time. The study shows that /sup 125/I absorptiometry can be used for continuous non-destructive measurements of root hard-tissue demineralization in vitro.

  11. Progress in Energy Storage Technologies: Models and Methods for Policy Analysis

    Science.gov (United States)

    Matteson, Schuyler W.

    Climate change and other sustainability challenges have led to the development of new technologies that increase energy efficiency and reduce the utilization of finite resources. To promote the adoption of technologies with social benefits, governments often enact policies that provide financial incentives at the point of purchase. In their current form, these subsidies have the potential to increase the diffusion of emerging technologies; however, accounting for technological progress can improve program success while decreasing net public investment. This research develops novel methods using experience curves for the development of more efficient subsidy policies. By providing case studies in the field of automotive energy storage technologies, this dissertation also applies the methods to show the impacts of incorporating technological progress into energy policies. Specific findings include learning-dependent tapering subsidies for electric vehicles based on the lithium-ion battery experience curve, the effects of residual learning rates in lead-acid batteries on emerging technology cost competitiveness, and a cascading diffusion assessment of plug-in hybrid electric vehicle subsidy programs. Notably, the results show that considering learning rates in policy development can save billions of dollars in public funds, while also lending insight into the decision of whether or not to subsidize a given technology.

  12. Recovery of valuable chlorosilane intermediates by a novel waste conversion process. Technical report for phase IIIA (final) and phase IIIB (progress)

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, K.E.

    1998-10-01

    From July 1994 through May 1998, direct process residue (DPR) hydrogenolysis has been studied in the laboratory, at a small Pilot Plant, and finally at a larger Pilot Plant within Dow Corning`s Carrollton, Kentucky plant. The system reacts filtered DPR with monomer at high temperature and pressure. The process demonstrates DPR conversion up to 86%. The reaction product contains high concentrations of valuable monomers such as dimethyldichlorosilane and methyldichlorosilane. A larger DPR hydrogenolysis reactor based on these results is being designed for operation in Europe at Dow Corning`s Barry, Wales site.

  13. Wind energy mission analysis. Final report, appendices A--J. [USA

    Energy Technology Data Exchange (ETDEWEB)

    1977-02-18

    Information is presented concerning meteorological data and supporting analyses, gross energy consumption patterns and end-use analysis, analysis for industrial applications of wind energy conversion systems (WECS), analysis for residential applications of WECS, analysis for application of WECS to communities remote from utility grids, analysis for agricultural applications of WECS, regional evaluation of the economics of wind turbine generation to the U. S. electric utility district, impact of storage on WECS, financial analysis techniques, and system spacing.

  14. Radiation Detection Scenario Analysis Toolbox (RADSAT) Test Case Implementation Final Report

    International Nuclear Information System (INIS)

    Final report for the project. This project was designed to demonstrate the use of the Radiation Detection Scenario Analysis Toolbox (RADSAT) radiation detection transport modeling package (developed in a previous NA-22 project) for specific radiation detection scenarios important to proliferation detection. This project was designed to demonstrate the use of the Radiation Detection Scenario Analysis Toolbox (RADSAT) radiation detection transport modeling package (developed in a previous NA-22 project) for specific radiation detection scenarios important to proliferation detection. RADSAT is founded on a 3-dimensional deterministic radiation transport solver capable of efficiently computing the radiation field at all points in complex, large-scale problems (e.g. buildings). These results are then coupled to a Monte Carlo detector response simulator. For this project Pacific Northwest National Laboratory (PNNL) staff applied RADSAT to two specific instruments and scenarios, in close collaboration with the developers of each technology. The first is a neutron-scatter camera for detection of concealed neutron-emitting sources developed at Sandia National Laboratories (SNL) and the second is a spent-fuel verification system for fuel assemblies in storage casks developed at Idaho National Laboratory (INL). To simulate detector responses, RADSAT uses a source modified version of Monte Carlo N-Particle Version 5 (MCNP5), which does not produce all of the information required to produce images for the scatter camera system. SNL models the scatter camera with Monte Carlo N-Particle - Politecnico di Milano (MCNP-PoliMi), which utilizes more accurate neutron elastic scattering physics and secondary gamma-ray production essential for modeling time-dependent events in multiple detectors. Therefore, RADSAT currently will not work for generating images for the scatter camera. However, it was demonstrated that RADSAT calculated the correct individual detector response, which

  15. Analysis of Exponential Distribution Under Adaptive Type-I Progressive Hybrid Censored Competing Risks Data

    Directory of Open Access Journals (Sweden)

    Mazen mohammed Nassar

    2014-08-01

    Full Text Available             A competing risks model based on exponential distribution is considered under adaptive type-I progressive hybrid censoring scheme. We investigate the maximum likelihood estimation and Bayesian estimation for the distribution parameter. The Bayes estimate of the unknown parameter is obtained based on squared error and LINEX loss functions under the assumption of gamma prior. The asymptotic confidence intervals, the Bayes credible intervals and two parametric bootstrap confidence intervals are also proposed. To evaluate the performance of the estimators, a simulation study is carried out. Normal 0 false false false EN-US X-NONE AR-SA

  16. Final Report for Geometric Analysis for Data Reduction and Structure Discovery DE-FG02-10ER25983, STRIPES award # DE-SC0004096

    Energy Technology Data Exchange (ETDEWEB)

    Vixie, Kevin R

    2014-11-27

    This is the final report for the project "Geometric Analysis for Data Reduction and Structure Discovery" in which insights and tools from geometric analysis were developed and exploited for their potential to large scale data challenges.

  17. Nuclear waste criticality analysis. Quarterly progress report, 1 October--31 December 1995

    International Nuclear Information System (INIS)

    The work to date includes the preparation of a report related to criticality in spent fuel, a report on the Oklo reactors and their relevance to Yucca Mountain, and the creation of a computer program to model the Oklo reactors. The objective of the program includes a computational model of the only known natural analogue to an underground nuclear waste repository and the possible application of the model to predict the long-term behavior of Yucca Mountain. A final summary of all work completed will be presented after the end of the project on February 29, 1996

  18. Multivariate analysis of progressive thermal desorption coupled gas chromatography-mass spectrometry.

    Energy Technology Data Exchange (ETDEWEB)

    Van Benthem, Mark Hilary; Mowry, Curtis Dale; Kotula, Paul Gabriel; Borek, Theodore Thaddeus, III

    2010-09-01

    Thermal decomposition of poly dimethyl siloxane compounds, Sylgard{reg_sign} 184 and 186, were examined using thermal desorption coupled gas chromatography-mass spectrometry (TD/GC-MS) and multivariate analysis. This work describes a method of producing multiway data using a stepped thermal desorption. The technique involves sequentially heating a sample of the material of interest with subsequent analysis in a commercial GC/MS system. The decomposition chromatograms were analyzed using multivariate analysis tools including principal component analysis (PCA), factor rotation employing the varimax criterion, and multivariate curve resolution. The results of the analysis show seven components related to offgassing of various fractions of siloxanes that vary as a function of temperature. Thermal desorption coupled with gas chromatography-mass spectrometry (TD/GC-MS) is a powerful analytical technique for analyzing chemical mixtures. It has great potential in numerous analytic areas including materials analysis, sports medicine, in the detection of designer drugs; and biological research for metabolomics. Data analysis is complicated, far from automated and can result in high false positive or false negative rates. We have demonstrated a step-wise TD/GC-MS technique that removes more volatile compounds from a sample before extracting the less volatile compounds. This creates an additional dimension of separation before the GC column, while simultaneously generating three-way data. Sandia's proven multivariate analysis methods, when applied to these data, have several advantages over current commercial options. It also has demonstrated potential for success in finding and enabling identification of trace compounds. Several challenges remain, however, including understanding the sources of noise in the data, outlier detection, improving the data pretreatment and analysis methods, developing a software tool for ease of use by the chemist, and demonstrating our belief

  19. Analysis of airborne radiometric data. Volume 2. Description, listing, and operating instructions for the code DELPHI/MAZAS. Final report

    International Nuclear Information System (INIS)

    The computer code DELPHI is an interactive English language command system for the analysis of airborne radiometric data. The code includes modules for data reduction, data simulation, time filtering, data adjustment and graphical presentation of the results. DELPHI is implemented in FORTRAN on a DEC-10 computer. This volume gives a brief set of operations instructions, samples of the output obtained from hard copies of the display on a Tektronix terminal and finally a listing of the code

  20. Analysis of airborne radiometric data. Volume 2. Description, listing, and operating instructions for the code DELPHI/MAZAS. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sperling, M.; Shreve, D.C.

    1978-12-01

    The computer code DELPHI is an interactive English language command system for the analysis of airborne radiometric data. The code includes modules for data reduction, data simulation, time filtering, data adjustment and graphical presentation of the results. DELPHI is implemented in FORTRAN on a DEC-10 computer. This volume gives a brief set of operations instructions, samples of the output obtained from hard copies of the display on a Tektronix terminal and finally a listing of the code.

  1. Engineering development of coal-fired high performance power systems, Phases 2 and 3. Quarterly progress report, October 1--December 31, 1996. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The goals of this program are to develop a coal-fired high performance power generation system (HIPPS) by the year 2000 that is capable of: {gt} 47% efficiency (HHV); NO{sub x}, SO{sub x}, and particulates {gt} 10% NSPS; coal providing {ge} 65% of heat input; all sold wastes benign; and cost of electricity 90% of present plant. Work reported herein is from Task 1.3 HIPPS Commercial Plant Design, Task 2,2 HITAF Air Heater, and Task 2.4 Duct Heater Design. The impact on cycle efficiency from the integration of various technology advances is presented. The criteria associated with a commercial HIPPS plant design as well as possible environmental control options are presented. The design of the HITAF air heaters, both radiative and convective, is the most critical task in the program. In this report, a summary of the effort associated with the radiative air heater designs that have been considered is provided. The primary testing of the air heater design will be carried out in the UND/EERC pilot-scale furnace; progress to date on the design and construction of the furnace is a major part of this report. The results of laboratory and bench scale activities associated with defining slag properties are presented. Correct material selection is critical for the success of the concept; the materials, both ceramic and metallic, being considered for radiant air heater are presented. The activities associated with the duct heater are also presented.

  2. Gonadotropin releasing hormone agonist treatment to increase final stature in children with precocious puberty: a meta-analysis.

    Science.gov (United States)

    Li, Pin; Li, Yan; Yang, Chung-Lin

    2014-12-01

    In the setting of central precocious puberty (CPP), the motivation for hormonal intervention is to help the child to reach a taller adult stature than she would achieve otherwise. While gonadotropin-releasing hormone analogs (GnRHa) constitute an established treatment for improving adult stature in girls presenting with CPP up to age 6 (true precocious puberty), it is not yet clear whether or not the same is true in the setting of CPP presented in girls beyond age 6 (advance puberty). GnRHa may slow growth velocity, offsetting the anticipated improvement in final height that should have resulted from the increased time before growth plate fusion. Consequently, it's been suggested that growth hormone (GH) should be combined with GnRHa to improve the results.Few controlled prospective studies have been performed with GnRHa in children and many conclusions rely in part on collective expert opinion. Therefore, the literature was searched and relevant studies were selected using the search terms "gonadotropin releasing hormone agonist," "precocious puberty/early puberty," and "GnRH analogue." After selected articles were screened for relevance, the process yielded 8 studies, the results of which were then pooled in a meta-analysis aimed at evaluating the effects of GnRHa therapy both with and without added GH in the setting of early puberty. A significant difference was elucidated in final height and predicted adult height comparing GnRHa and combined GnRHa/GH groups. However, no significant difference was elucidated in final height standard deviation scores (SDS) and initial height SDS when comparing GnRHa and control groups. At the same time, the final analysis revealed no significant difference in final height SDS and initial height SDS when GnRHa and combined GnRHa/GH groups were compared.The results suggest GnRHa therapy may have a positive effect on final adult height in girls with early puberty, while adding GH to the treatment may suggest more advantage

  3. Analysis of Gross Domestic Product Evolution under the Influence of the Final Consumption

    OpenAIRE

    Constantin ANGHELACHE; Diana Valentina SOARE; Marius POPOVICI

    2015-01-01

    This paper will focus on the possible correlation between the evolution of the final consumption and the dynamics of the Gross Domestic Product. The authors have applied the linear regression method in order to draw a coherent model, whose parameters were tested by using proper instruments.

  4. Thermodynamic analysis of universes with the initial and final de-Sitter eras

    OpenAIRE

    Moradpour, H.; Sabet, M. T. Mohammadi; Ghasemi, A.

    2015-01-01

    Our aim is studying the thermodynamics of cosmological models including initial and final de-Sitter eras. For this propose, bearing Cai-Kim temperature in mind, we investigate the thermodynamic properties of a dark energy candidate with variable energy density, and show that the state parameter of this dark energy candidate should obey the $\\omega_D\

  5. Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma

    International Nuclear Information System (INIS)

    The development of esophageal squamous cell carcinoma (ESCC) progresses a multistage process, collectively known as precursor lesions, also called dysplasia (DYS) and carcinoma in situ (CIS), subsequent invasive lesions and final metastasis. In this study, we are interested in investigating the expression of a variety of functional classes of proteins in ESCC and its precursor lesions and characterizing the correlation of these proteins with ESCC malignant progression. Fas, FADD, caspase 8, CDC25B, fascin, CK14, CK4, annexin I, laminin-5γ2 and SPARC were analyzed using immunohistochemistry on tissue microarray containing 205 ESCC and 173 adjacent precursor lesions as well as corresponding normal mucosa. To confirm the immunohistochemical results, three proteins, fascin, CK14 and laminin-5γ2, which were overexpressed in ESCC on tissue microarray, were detected in 12 ESCC cell lines by Western blot assay. In ESCC and its precursor lesions, FADD, CDC25B, fascin, CK14, laminin-5γ2 and SPARC were overexpressed, while Fas, caspase 8, CK4 and annexin I were underexpressed. The abnormalities of these proteins could be classified into different groups in relation to the stages of ESCC development. They were 'early' corresponding to mild and moderate DYS with overexpression of fascin, FADD and CDC25B and underexpression of Fas, caspase 8, CK4 and annexin I, 'intermediate' to severe DYS and CIS with overexpression of FADD and CK14, and 'late' to invasive lesions (ESCC) and to advanced pTNM stage ESCC lesions with overexpression of CK14, laminin-5γ2 and SPARC. Analyzing the protein expression patterns of Fas, FADD, caspase 8, CDC25B, fascin, CK14, CK4, annexin I, laminin-5γ2 and SPARC would be valuable to develop rational strategies for early detection of lesions at risk in advance as well as for prevention and treatment of ESCC

  6. Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    He Zu-gen

    2006-12-01

    Full Text Available Abstract Background The development of esophageal squamous cell carcinoma (ESCC progresses a multistage process, collectively known as precursor lesions, also called dysplasia (DYS and carcinoma in situ (CIS, subsequent invasive lesions and final metastasis. In this study, we are interested in investigating the expression of a variety of functional classes of proteins in ESCC and its precursor lesions and characterizing the correlation of these proteins with ESCC malignant progression. Methods Fas, FADD, caspase 8, CDC25B, fascin, CK14, CK4, annexin I, laminin-5γ2 and SPARC were analyzed using immunohistochemistry on tissue microarray containing 205 ESCC and 173 adjacent precursor lesions as well as corresponding normal mucosa. To confirm the immunohistochemical results, three proteins, fascin, CK14 and laminin-5γ2, which were overexpressed in ESCC on tissue microarray, were detected in 12 ESCC cell lines by Western blot assay. Results In ESCC and its precursor lesions, FADD, CDC25B, fascin, CK14, laminin-5γ2 and SPARC were overexpressed, while Fas, caspase 8, CK4 and annexin I were underexpressed. The abnormalities of these proteins could be classified into different groups in relation to the stages of ESCC development. They were "early" corresponding to mild and moderate DYS with overexpression of fascin, FADD and CDC25B and underexpression of Fas, caspase 8, CK4 and annexin I, "intermediate" to severe DYS and CIS with overexpression of FADD and CK14, and "late" to invasive lesions (ESCC and to advanced pTNM stage ESCC lesions with overexpression of CK14, laminin-5γ2 and SPARC. Conclusion Analyzing the protein expression patterns of Fas, FADD, caspase 8, CDC25B, fascin, CK14, CK4, annexin I, laminin-5γ2 and SPARC would be valuable to develop rational strategies for early detection of lesions at risk in advance as well as for prevention and treatment of ESCC.

  7. Verification of state and progress of a biological remediation of NAPL contaminated soil by the determination of radon concentration in soil air. Final report

    International Nuclear Information System (INIS)

    Some methods for recycling of soil which is contaminated with hydrocarbons like petrol or diesel are based on the admixture of active biological material in order to reduce the contamination. This mixture is stored on a dump for some months and the reduction of the contamination is checked by regular chemical analysis of some samples. Task of the research project is to replace these analysis by an investigation of Radon gas, which is present in the pore volume of the dumped soil. In two series of experiments at dumps with contaminated soil biologically treated, an increase of radon concentration in conjunction with a decrease of contamination was detected. But the recorded change of Radon was much less than expected and shows a significant dependence on environmental parameters like temperature or soil structure. At the present state of development the method is not yet suitable to replace conventional analysis during soil recycling. (orig.)

  8. Procedure for conducting a human-reliability analysis for nuclear power plants. Final report

    International Nuclear Information System (INIS)

    This document describes in detail a procedure to be followed in conducting a human reliability analysis as part of a probabilistic risk assessment when such an analysis is performed according to the methods described in NUREG/CR-1278, Handbook for Human Reliability Analysis with Emphasis on Nuclear Power Plant Applications. An overview of the procedure describing the major elements of a human reliability analysis is presented along with a detailed description of each element and an example of an actual analysis. An appendix consists of some sample human reliability analysis problems for further study

  9. Transportation routing analysis geographic information system - tragis, progress on improving a routing tool

    International Nuclear Information System (INIS)

    The Transportation Routing Analysis Geographic Information System (TRAGIS) model provides a useful tool to calculate and analyze transportation routes for radioactive materials within the continental United States. This paper outlines some of the features available in this model. (authors)

  10. Transportation Routing Analysis Geographic Information System -- TRAGIS, progress on improving a routing tool

    International Nuclear Information System (INIS)

    The Transportation Routing Analysis Geographic Information System (TRAGIS) model provides a useful tool to calculate and analyze transportation routes for radioactive materials within the continental US. This paper outlines some of the features available in this model

  11. The National Food and Nutrient Analysis Program: A decade of progress

    OpenAIRE

    Haytowitz, David B.; Pehrsson, Pamela R.; Holden, Joanne M

    2008-01-01

    The National Food and Nutrient Analysis Program (NFNAP) was designed to expand the quantity and improve the quality of data in the United States Department of Agriculture (USDA) food composition databases through the collection and analysis of nationally representative samples of foods and beverages. This paper describes some of the findings from the NFNAP and its impact on the food composition databases produced by USDA. The NFNAP employs statistically valid sampling plans, comprehensive qua...

  12. Nuclear design and analysis of ITER: Progress report, November 15, 1987--November 14, 1988

    International Nuclear Information System (INIS)

    Over the past year we participated in the ITER design effort. The contribution of the Fusion Technology Institute at the University of Wisconsin was mainly in the Nuclear Design and Analysis area. The activities included the inboard shield design, the aqueous Li salt blanket design, and the development of blanket evaluation criteria to be used for blanket selection. This paper describes the analysis performed in each of these areas and discusses the major finds. 20 refs., 12 figs., 7 tabs

  13. Progress Analysis of Library Knowledge Management Research in China Based on Bibliometrics

    OpenAIRE

    Zhong Wenjuan; Wu Xuezhi; Zhao Tieqin

    2013-01-01

    Knowledge management has been the general concern of the academic community, library knowledge management is one of its important applications. Take journal articles at China National Knowledge Infrastructure and books published in China from 1999 to 2012 as data sources. Applying bibliometrics and content analysis, the authors try to statistics relevant literature on Chinese library knowledge management and make a detailed analysis: the study on library knowledge management in China experien...

  14. Plasma Science Committee (PLSC) and the Panel on Opportunities in Plasma Science and Technology (OPST). Final technical progress report, 1 June 1993--31 May 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    The Plasma Science Committee (PLSC) of the National Research Council (NRC) is charged with monitoring the health of the field of plasma science in the United States. Accordingly, the Committee identifies and examines both broad and specific issues affecting the field. Regular meetings, teleconferences, briefings from agencies and the scientific community, the formation of study panels to prepare reports, and special symposia are among the mechanisms used by the PLSC to meet its charge. This progress report presents a review of PLSC activities from June 1, 1993 to May 31, 1994. The details of prior activities are discussed in earlier reports. This report also includes the status of activities associated with the PLSC study on opportunities in plasma science and technology. During the above period, the PLSC continued to track and participate in, when requested, discussions on the health of the field. Much of the perspective of the PLSC has been presented in its report Research Briefing on Contemporary Problems in Plasma Science. That report not only has served as the basis for briefings to representatives of the federal government and the community-at-large, but also served as the starting point for the Panel on Opportunities in Plasma Science and Technology (OPST) as it began an assessment of the field. The PLSC also continued its follow-up briefings and discussions on the results of the report Plasma Processing of Materials: Scientific and Technological Opportunities (PPPM). As a result of these activities, the Committee is now working with the NRC Committee on Atomic, Molecular, and Optical Sciences (CAMOS) to organize a symposium on database needs in plasma processing of materials.

  15. Multiobjective Integrated Decision Analysis System (MIDAS): Volume 1, Model overview: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Farber, M.; Brusger, E.; Gerber, M.

    1988-04-01

    MIDAS (Multiobjective Integrated Decision Analysis System) is an innovative utility planning tool that facilitates the analysis of risk. Three features distinguish this framework from other planning models: it incorporates a generalized decision analysis approach; it includes a completely integrated planning model for demand-supply evaluation; and the complete model runs on a microcomputer. 24 figs.

  16. Transcriptomic gene-network analysis of exposure to silver nanoparticle reveals potentially neurodegenerative progression in mouse brain neural cells.

    Science.gov (United States)

    Lin, Ho-Chen; Huang, Chin-Lin; Huang, Yuh-Jeen; Hsiao, I-Lun; Yang, Chung-Wei; Chuang, Chun-Yu

    2016-08-01

    Silver nanoparticles (AgNPs) are commonly used in daily living products. AgNPs can induce inflammatory response in neuronal cells, and potentially develop neurological disorders. The gene networks in response to AgNPs-induced neurodegenerative progression have not been clarified in various brain neural cells. This study found that 3-5nm AgNPs were detectable to enter the nuclei of mouse neuronal cells after 24-h of exposure. The differentially expressed genes in mouse brain neural cells exposure to AgNPs were further identified using Phalanx Mouse OneArray® chip, and permitted to explore the gene network pathway regulating in neurodegenerative progression according to Cytoscape analysis. In focal adhesion pathway of ALT astrocytes, AgNPs induced the gene expression of RasGRF1 and reduced its downstream BCL2 gene for apoptosis. In cytosolic DNA sensing pathway of microglial BV2 cells, AgNPs reduced the gene expression of TREX1 and decreased IRF7 to release pro-inflammatory cytokines for inflammation and cellular activation. In MAPK pathway of neuronal N2a cells, AgNPs elevated GADD45α gene expression, and attenuated its downstream PTPRR gene to interfere with neuron growth and differentiation. Moreover, AgNPs induced beta amyloid deposition in N2a cells, and decreased PSEN1 and PSEN2, which may disrupt calcium homeostasis and presynaptic dysfunction for Alzheimer's disease development. These findings suggested that AgNPs exposure reveals the potency to induce the progression of neurodegenerative disorder. PMID:27131904

  17. Tumor progression: analysis of the instability of the metastatic phenotype, sensitivity to radiation and chemotherapy

    International Nuclear Information System (INIS)

    The major complications for tumor therapy are 1) tumor spread (metastasis); 2) the mixed nature of tumors (heterogeneity); and 3) the capacity of tumors to evolve (progress). To study these tumor characteristics, the rat 13762NF mammary adenocarcinoma was cloned and studied for metastatic properties and sensitivities to therapy (chemotherapy, radiation and hyperthermia). The cell clones were heterogeneous and no correlation between metastatic potential and therapeutic sensitivities was observed. Further, these phenotypes were unstable during pasage in vitro; yet, the changes were clone dependent and reproducible using different cryoprotected cell stocks. To understand the phenotypic instability, subclones were isolated from low and high passage cell clones. The results demonstrated that 1) tumor cells are heterogeneous for multiple phenotypes; 2) tumor cells are unstable for multiple phenotypes; 3) the magnitude, direction and time of occurrence of phenotypic drift is clone dependent; 4) the sensitivity of cell clones to ionizing radiation (γ or heat) and chemotherapy agents is independent of their metastatic potential; 5) shifts in metastatic potential and sensitivity to therapy may occur simultaneously but are not linked; and 6) tumor cells independently diverge to form several subpopulations with unique phenotypic profiles

  18. Regional Fertility Transition in India: An Analysis Using Synthetic Parity Progression Ratios

    Directory of Open Access Journals (Sweden)

    Thomas Spoorenberg

    2012-01-01

    Full Text Available This paper examines various aspects of regional fertility transition in India. Using nationally representative data from three rounds of National Family Health Surveys (NFHSs conducted in India, we compare and contrast fertility patterns in six regions of India for the period between 1977 and 2004. To study the fertility patterns, we use synthetic parity progression ratios which, besides providing estimates for average lifetime parity, also allow for decomposition of lifetime parity by birth order. The paper also examines changes in birth intervals over time and across the six regions. The results confirm the persistence of regional differences in fertility. However, in all regions fertility is declining and it is possible that fertility rates will converge in the near future. The main reason for fertility decline in all regions is the reduction in third- and higher-order births. There has not been any significant decline in first and second births, even in regions with low fertility. In addition to the discussion of the substantive results, the paper also comments on the quality of NFHS data.

  19. Progress report on neutron activation analysis at Dalat Nuclear Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tuan, Nguyen Ngoc [Nuclear Research Institute, Dalat (Viet Nam)

    2003-03-01

    Neutron Activation Analysis (NAA) is one of most powerful techniques for the simultaneous multi-elements analysis. This technique has been studied and applied to analyze major, minor and trace elements in Geological, Biological and Environmental samples at Dalat Nuclear Research Reactor. At the sixth Workshop, February 8-11, 1999, Yojakarta, Indonesia we had a report on Current Status of Neutron Activation Analysis using Dalat Nuclear Research Reactor. Another report on Neutron Activation Analysis at the Dalat Nuclear Research Reactor also was presented at the seventh Workshop in Taejon, Korea from November 20-24, 2000. So in this report, we would like to present the results obtained of the application of NAA at NRI for one year as follows: (1) Determination of the concentrations of noble, rare earth, uranium, thorium and other elements in Geological samples according to requirement of clients particularly the geologists, who want to find out the mineral resources. (2) The analysis of concentration of radionuclides and nutrient elements in foodstuffs to attend the program on Asian Reference Man. (3) The evaluation of the contents of trace elements in crude oil and basement rock samples to determine original source of the oil. (4) Determination of the elemental composition of airborne particle in the Ho Chi Minh City for studying air pollution. The analytical data of standard reference material, toxic elements and natural radionuclides in seawater are also presented. (author)

  20. Progress report on neutron activation analysis at Dalat Nuclear Research Reactor

    International Nuclear Information System (INIS)

    Neutron Activation Analysis (NAA) is one of most powerful techniques for the simultaneous multi-elements analysis. This technique has been studied and applied to analyze major, minor and trace elements in Geological, Biological and Environmental samples at Dalat Nuclear Research Reactor. At the sixth Workshop, February 8-11, 1999, Yojakarta, Indonesia we had a report on Current Status of Neutron Activation Analysis using Dalat Nuclear Research Reactor. Another report on Neutron Activation Analysis at the Dalat Nuclear Research Reactor also was presented at the seventh Workshop in Taejon, Korea from November 20-24, 2000. So in this report, we would like to present the results obtained of the application of NAA at NRI for one year as follows: (1) Determination of the concentrations of noble, rare earth, uranium, thorium and other elements in Geological samples according to requirement of clients particularly the geologists, who want to find out the mineral resources. (2) The analysis of concentration of radionuclides and nutrient elements in foodstuffs to attend the program on Asian Reference Man. (3) The evaluation of the contents of trace elements in crude oil and basement rock samples to determine original source of the oil. (4) Determination of the elemental composition of airborne particle in the Ho Chi Minh City for studying air pollution. The analytical data of standard reference material, toxic elements and natural radionuclides in seawater are also presented. (author)

  1. Assessment of uncertainties in risk analysis of chemical establishments. The ASSURANCE project. Final summary report

    DEFF Research Database (Denmark)

    Lauridsen, K.; Kozine, Igor; Markert, Frank;

    2002-01-01

    This report summarises the results obtained in the ASSURANCE project (EU contract number ENV4-CT97-0627). Seven teams have performed risk analyses for the same chemical facility, an ammonia storage. The EC's Joint Research Centre at Ispra and RisøNational Laboratory co-ordinated the exercise and...... ranking among the adherents of the probabilistic approach. Breaking down the modelling of both frequencyand consequence assessments into suitably small elements and conducting case studies allowed identifying root causes of uncertainty in the final risk assessments. Large differences were found in both...... the frequency assessments and in the assessment ofconsequences. The report gives a qualitative assessment of the importance to the final calculated risk of uncertainties in assumptions made, in the data and the calculation methods used. This assessment can serve as a guide to areas where, in...

  2. Final hazard classification and auditable safety analysis for the 105-C Reactor Interim Safe Storage Project

    International Nuclear Information System (INIS)

    This document summarizes the inventories of radioactive and hazardous materials present in the 105-C Reactor Facility and the operations associated with the Interim Safe Storage Project which includes decontamination and demolition and interim safe storage of the remaining facility. This document also establishes a final hazard classification and verifies that appropriate and adequate safety functions and controls are in place to reduce or mitigate the risk associated with those operations

  3. Thermodynamic analysis of universes with the initial and final de Sitter eras

    Science.gov (United States)

    Moradpour, H.; Sabet, M. T. Mohammadi; Ghasemi, A.

    2015-08-01

    Our aim is studying the thermodynamics of cosmological models including initial and final de Sitter eras. For this propose, bearing Cai-Kim temperature in mind, we investigate the thermodynamic properties of a dark energy (DE) candidate with variable energy density, and show that the state parameter of this dark energy candidate (ωD) should obey the ωD≠ - 1 constraint, whiles there is no interaction between the fluids filled the universe, and the universe is not in the de Sitter eras. Additionally, based on the thermal fluctuation theory, we study the possibility of inducing fluctuations to the entropy of the DE candidate due to a mutual interaction between the cosmos sectors. Therefore, we find a relation between the thermal fluctuations and the mutual interaction between the cosmos sectors, whiles the DE candidate has a varying energy density. Finally, bearing the coincidence problem in mind, we derive a constraint on the vacuum energy, and investigate its relation with the entropy evolution of the DE candidate. We also point to a model with initial and final de Sitter eras in which a gravitationally induced particle production process leads to change the expansion eras, whiles the corresponding pressure is considered as the cause of current accelerated phase. We study its thermodynamics, and show that such processes may also leave thermal fluctuations into the system. We also find an expression between the thermal fluctuations and the particle production rate. Finally, we use Hayward-Kodama temperature to get a relation for the horizon entropy in models including the gravitationally induced particle production process. Our study shows that the first law of thermodynamics is available on the apparent horizon whiles, the gravitationally induced particle production process, as the DE candidate, may add an additional term to the Bekenstein limit of the horizon. The relation between the validity of the second law of thermodynamics and the gravitationally particle

  4. Progress of neutron induced prompt gamma analysis technique in 1988~2003

    Institute of Scientific and Technical Information of China (English)

    JING Shi-Wei; LIU Yu-Ren; CHI Yan-Tao; TIAN Yu-Bing; CAO Xi-Zheng; ZHAO Xin-Hui; REN Wan-Bin; LIU Lin-Mao

    2004-01-01

    This paper describes new development of the neutron induced prompt gamma-ray analysis (NIPGA) technology in 1988~2003. The pulse fast-thermal neutron activation analysis method, which utilized the inelastic re action and capture reaction jointly, was employed to measure the elemental contents more efficiently. Lifetime of the neutron generator was more than 10000h and the performance of detector and MCA reached a high level. At the same time, Monte Carlo library least-square method was used to solve the nonlinearity problem in the NIPGA.

  5. SPECT-CT and PET-CT progress in the research of computer analysis method

    Directory of Open Access Journals (Sweden)

    Jingang Guo

    2015-04-01

    Full Text Available The development of multimodal imaging equipment is milestone in the development of imaging, after the PET-CT, American GE company launched a Discovery 670 NM/CT, CT and SPECT, the organic integration of the formation of SPECT-CT new molecular medical imaging equipment, with SPECT, CT and PET-CT is getting more and more widely attention and application, many of SPECT-CT and PET-CT image analysis computer method arises at the historic moment, getting increasing attention of the clinical and imaging science. The paper carried on the detailed description of the SPECT-CT and PET-CT computer analysis method.

  6. Coal to SNG: Technical progress, modeling and system optimization through exergy analysis

    International Nuclear Information System (INIS)

    Highlights: • Technical progresses of coal to SNG technologies are reported. • The entire coal to SNG system is modeled. • Coupling between SNG production and power generation is investigated. • Breakthrough points for further energy saving are determined. • System performance is optimized based on the first and second laws of thermodynamics. - Abstract: For both energy security and CO2 emission reduction, synthetic natural gas (SNG) production from coal is an important path to implement clean coal technologies in China. In this paper, an overview of the progress of coal to SNG technologies, including the development of catalysts, reactor designs, synthesis processes, and systems integration, is provided. The coal to SNG system is modeled, the coupling between SNG production and power generation is investigated, the breakthrough points for further energy savings are determined, and the system performance is optimized based on the first and the second laws of thermodynamics. From the viewpoint of the first law of thermodynamics, the energy conversion efficiency of coal to SNG system can reach 59.8%. To reduce the plant auxiliary power, the breakthrough points are the development of low-energy-consumption oxygen production technology and gas purification technology or seeking new oxidants for coal gasification instead of oxygen. From the viewpoint of the second law of thermodynamics, the major exergy destruction in a coal to SNG system occurs in the coal gasification unit, SNG synthesis unit and the raw syngas cooling process. How to reduce the exergy destruction in these units is the key to energy savings and system performance enhancement. The conversion ratio of the first SNG synthesis reactor and the split ratio of the recycle gas are key factors that determine the performance of both the SNG synthesis process and the whole plant. A “turning point” phenomenon is observed: when the split ratio is higher than 0.90, the exergy destruction of the SNG

  7. Environmental analysis of endocrine disrupting effects from hydrocarbon contaminants in the ecosystem. 1998 annual progress report

    International Nuclear Information System (INIS)

    'The objective of this project is to determine how environmental contaminants, namely hydrocarbons, can act as hormones or anti-hormones (i.e., environmental hormones) in different species present in aquatic ecosystems. Species of particular focus are those which can serve as sentinel species (e.g., amphibians) and, thus, provide early warning signals for more widespread impacts on an ecosystem and its wildlife and human inhabitants. This reports the progress of 1.5 years of a three-year grant awarded to the Tulane/Xavier Center for Bioenvironmental Research (CBR). A growing body of evidence suggests that chemicals in the environment can disrupt the endocrine system of animals (i.e., wildlife and humans) and adversely impact the development of these species. Because of the multitude of known endocrine-disrupting chemicals and the numerous industrial and government sectors producing these chemicals, almost every federal agency has initiated research on the endocrine effects of chemicals relevant to their operations. This study represents the Department of Energy (DOE) Basic Energy Sciences'' only research on the impacts of endocrine-disrupting chemicals. The activities employed by this project to determine these impacts include development of biotechnology screens (in vitro), animal screens (in vivo), and other analyses of aquatic ecosystem biomarkers of exposure. The results from this study can elucidate how chemicals in the environment, including those from DOE activities, can signal (and alter) the development of a number of species in aquatic ecosystems. These signals can have detrimental impacts not only on an organismal level, but also on community, population, and entire ecosystem levels, including humans.'

  8. Progressive Trends and Impact of the Journal of Career Development: A Citation Analysis

    Science.gov (United States)

    Chaichanasakul, Adipat; He, Yuhong; Chen, Hsui-Hui; Allen, G. E. Kawika; Khairallah, Taleb S.; Ramos, Karina

    2011-01-01

    As one of the four premier journals in vocational psychology, the "Journal of Career Development" ("JCD") has published over 830 articles over the past three decades. This study examined the performance of "JCD" through a citation analysis and provided evaluative data for scholars publishing in the field of vocation psychology. Articles published…

  9. Undergraduate Work Placements: An Analysis of the Effects on Career Progression

    Science.gov (United States)

    Brooks, Ruth; Youngson, Paul L.

    2016-01-01

    Combining work experience with degree-level study is seen as a key differentiator for securing employment upon graduation in a competitive employment market. The positive benefits of sandwich courses, where up to 12 months is spent working in industry, are widely acknowledged in academic literature though data analysis tends to focus on cohorts in…

  10. The debris module: An effective tool for the analysis of melt progression in LWRs

    International Nuclear Information System (INIS)

    The DEBRIS module was developed to deal with the analysis of core melt processes in light water reactors (LWR's). It was designed to address the important processes associated with the late phase of a core meltdown. This phase encompasses the period following the loss of intact rod geometry and ending with vessel head failure. It is characterized by the melting and relocation of ceramic rich materials through a rubblized medium composed primarily of fuel pellet and oxidized cladding fragments. Of particular interest are the dynamics of the melting process, the relocation of the components, the formation of crusts, retention of molten materials by the crust, and remelting of crusts.'ne DEBRIS module treats these processes in a two-dimensional (r,z) geometry solving the continuity, momentum, and energy equations to describe the dynamics of meltdown. The DEBRIS models are described together with some of the analyses to which the module has been applied. In particular, a description is given of the DEBRIS module analysis of the MP-1 experiment. The DEBRIS module appears to have significant potential for the analysis of late phase meltdown processes and can be effectively used both in a stand-alone mode or in conjunction with the severe accident analysis codes (MELCOR, SCDAP). In addition, the module may prove effective for treatment of the early phase processes as well

  11. Research in progress in applied mathematics, numerical analysis, and computer science

    Science.gov (United States)

    1990-01-01

    Research conducted at the Institute in Science and Engineering in applied mathematics, numerical analysis, and computer science is summarized. The Institute conducts unclassified basic research in applied mathematics in order to extend and improve problem solving capabilities in science and engineering, particularly in aeronautics and space.

  12. Design rules of mechanical structure of reactors. Damage due to cyclic loading. Progressive distortion. Practical analysis of ratcheting

    International Nuclear Information System (INIS)

    At first is given a definition of what is ratcheting. A short discussion shows that computation results do not agree with experimental results. This is attributed to the complexity of the real material behavior. These considerations lead to try to build a design rule mainly based on the results of experimental tests. A large experimental program is in progress at CEN-Saclay. Using these results and the results available in open litterature, it was possible to propose a rule based on the concept of effective primary stress Psub(eff). The effective primary stress is a fictitious primary stress giving the same effects that the real loading (it is to say the same effect that the combination of an applied primary stress P and a cyclic straining). Determination of an upper bound value of Psub(eff) is made with the help of an efficiency diagram. More precisely the efficiency diagram include a curve giving a conservative value of an efficiency index V=P/Psub(eff) as a function of the secondary quotient SQ=ΔQ/P. Finally limitation of Psub(eff) intensity is discussed in regard with the current practice

  13. Nuclear analysis of ITER. Progress report, November 15, 1996--November 14, 1997

    International Nuclear Information System (INIS)

    Over the past year the authors participated in the ITER EDA design effort as part of the US home team. Significant contribution was provided by the Fusion Technology Institute (FTI) at the University of Wisconsin (UW) in the areas of neutronics, shielding and activation analyses. During the first quarter of FY97, they continued working on the design tasks D307 and D308 of calendar year 1996. Most of the effort in the activation area was devoted to providing support for the building dose calculations. The work on these tasks was finished and the final reports were written and submitted to the JCT. During the year 1997, the FTI was involved in performing several multi-dimensional neutronics, shielding, and activation calculations for the blanket and divertor designs and recent design changes. Their effort concentrated on implementing the changes in the divertor cassette design that has been nearly fully developed. Calculations were performed to determine the nuclear parameters in the divertor cassettes and surrounding components. Neutronics and shielding analyses were performed also for the diagnostic cassettes. The results of the three-dimensional neutronics calculations for the divertor cassette were utilized to perform activation calculations that take into account the self-shielding effects resulting from the giant resonances in the tungsten activation cross sections. A report on the activities performed is given here

  14. HTGR accident initiation and progression analysis status report. Volume VIII. Responses to comments on AIPA status report

    International Nuclear Information System (INIS)

    The first seven volumes of the report series provide formal documentation of the status of the ERDA-sponsored Accident Initiation and Progression Analysis (AIPA) study as of the end of FY75. That portion of the report was given broad distribution to government agencies, industrial organizations, and academic institutions. Comments on the Status Report have been actively solicited from these and other organizations. The volume presented (the eighth in the AIPA Status Report) documents all of the formal written comments that have been received as of September 30, 1976, together with the responses to those comments. The comments as presented are direct quotations from the manuscripts as submitted by the reviewers; none have been paraphrased. The comments are presented in the same order as submitted by the reviewers and are generally addressed individually

  15. Failure analysis and failure prevention in electric power systems. Annual progress report No. 1

    International Nuclear Information System (INIS)

    Six technical tasks have been identified as necessary to achieve the program goal of increased reliability and safety of electric power plants. Analysis of past operating and malfunction experience (Task I) has been used to identify problem areas which are potentially hazardous or costly and which should be subjected to detailed engineering analysis (Task II) or simulation tests (Task V). Input data on the actual environment and loading (Task III) and on the materials and structural properties (Task IV) have been obtained, and specific engineering analyses have been performed. Tasks I-V have provided a quantitative basis for developing improved failure prediction and prevention programs (Task VI). The analyses completed include flaw indictions in the nozzle to shell weld of the Pilgrim 1 vessel, a corner crack in the nozzle of a test pressure vessel, a crack in a butt weld under the influence of residual stresses, and flaws in the near bore area of steam turbine rotors

  16. Progress in press forming computer aided analysis for high strength steel sheet applications

    Science.gov (United States)

    Hiramoto, Jiro; Urabe, Masaki; Ishiwatari, Akinobu; Urabe, Toshiaki

    2013-12-01

    The development of press-forming analysis technologies is important to expand the application of high strength steel sheets to automotive body structures. In general, there are various problems in the forming process of high strength steel sheets. In this study the improvements in the prediction accuracy of stretch-flange-fracture and springback were especially focused. In terms of the prediction accuracy of stretch-flange-fracture, a new stretch-flange-fracture prediction technology was developed based on a maximum principal strain gradient. It enables the accurate prediction of stretch- flange-fracture in press-forming of practical parts. On the other hand, springback prediction technologies were developed to solve springback problems. It is very important to clarify the root cause of springback in order to control. Therefore, a new method of springback factor analysis was developed, which can extract the areas and residual stresses which have major impacts on springback at press-forming.

  17. Progress in Top-Down Proteomics and the Analysis of Proteoforms

    Science.gov (United States)

    Toby, Timothy K.; Fornelli, Luca; Kelleher, Neil L.

    2016-06-01

    From a molecular perspective, enactors of function in biology are intact proteins that can be variably modified at the genetic, transcriptional, or post-translational level. Over the past 30 years, mass spectrometry (MS) has become a powerful method for the analysis of proteomes. Prevailing bottom-up proteomics operates at the level of the peptide, leading to issues with protein inference, connectivity, and incomplete sequence/modification information. Top-down proteomics (TDP), alternatively, applies MS at the proteoform level to analyze intact proteins with diverse sources of intramolecular complexity preserved during analysis. Fortunately, advances in prefractionation workflows, MS instrumentation, and dissociation methods for whole-protein ions have helped TDP emerge as an accessible and potentially disruptive modality with increasingly translational value. In this review, we discuss technical and conceptual advances in TDP, along with the growing power of proteoform-resolved measurements in clinical and translational research.

  18. On the Partial-Wave Analysis of Mesonic Resonances Decaying to Multiparticle Final States Produced by Polarized Photons

    CERN Document Server

    Salgado, Carlos W

    2013-01-01

    Meson spectroscopy is going through a revival with the advent of high statistics experiments and new advances in the theoretical predictions. The Constituent Quark Model (CQM) is finally being expanded considering more basic principles of field theory and using discrete calculations of Quantum Chromodynamics (lattice QCD). These new calculations are approaching predictive power for the spectrum of hadronic resonances and decay modes. It will be the task of the new experiments to extract the meson spectrum from the data and compare with those predictions. The goal of this report is to describe one particular technique for extracting resonance information from multiparticle final states. The technique described here, partial wave analysis based on the helicity formalism, has been used at Brookhaven National Laboratory (BNL) using pion beams, and Jefferson Laboratory (JLab) using photon beams. In particular this report broaden this technique to include production experiments using linearly polarized real photons...

  19. The “Iron Screen”: Progressive Development of an Interpretative Analysis of Body Iron Status

    OpenAIRE

    Beck, J. Robert; Turpin, Edward H.; Rawnsley, Howard M

    1982-01-01

    The Iron Screen, a sequential Bayesian decision-making model for the assessment of body iron stores in man, is a special example of the blending of computer support, decision analysis, and multivariate statistical techniques in medicine. This model, originally developed and tested in patients with chronic diseases and a question of iron deficiency anemia, has recently been broadened to include all pateints for whom body iron stores must be determined. In this report we describe operational ex...

  20. A Two-step Approach to Progressive Collapse Analysis of Building Structures under Blast Loading

    Institute of Scientific and Technical Information of China (English)

    XU Jun-xian; LIU Xi-la

    2009-01-01

    Structural collapse under blast loads is a very complex process. For several decades, the engineering profession has considered some approaches to analyze the essential physics of collapse phenomena. Recently, the interest in this topic has risen to an apex since the collapse of the World Trade Center towers. A two-step analysis approach to capture the characteristics of structural collapse during explosions is proposed. A numerical example is presented to illustrate the performance of the presented approach.

  1. Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS)

    OpenAIRE

    O'Connell Thomas M; Staab Jennifer M; Gomez Shawn M

    2010-01-01

    Abstract Background Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentrations or profiles in response to perturbation through disease, toxicants or drugs. The spectra generated through such analyses are typically confounded by noise of various types, obscuring the signals and hindering downstream statistical analysis. Such issues are becoming increasingly significant as greater numb...

  2. Continuum Damage Mechanics Models for the Analysis of Progressive Failure in Open-Hole Tension Laminates

    Science.gov (United States)

    Song, Kyonchan; Li, Yingyong; Rose, Cheryl A.

    2011-01-01

    The performance of a state-of-the-art continuum damage mechanics model for interlaminar damage, coupled with a cohesive zone model for delamination is examined for failure prediction of quasi-isotropic open-hole tension laminates. Limitations of continuum representations of intra-ply damage and the effect of mesh orientation on the analysis predictions are discussed. It is shown that accurate prediction of matrix crack paths and stress redistribution after cracking requires a mesh aligned with the fiber orientation. Based on these results, an aligned mesh is proposed for analysis of the open-hole tension specimens consisting of different meshes within the individual plies, such that the element edges are aligned with the ply fiber direction. The modeling approach is assessed by comparison of analysis predictions to experimental data for specimen configurations in which failure is dominated by complex interactions between matrix cracks and delaminations. It is shown that the different failure mechanisms observed in the tests are well predicted. In addition, the modeling approach is demonstrated to predict proper trends in the effect of scaling on strength and failure mechanisms of quasi-isotropic open-hole tension laminates.

  3. Bulk hydrogen analysis, using neutrons. Final report of the second research co-ordination meeting

    International Nuclear Information System (INIS)

    The aims of the Second Co-ordination Meting (RCM) of the Coordinated Research Programme (CRP) were to report on and review progress against the work programme set at the beginning of the CRP and to discuss the work plans for the second half of the programme. In many cases hydrogen is required to be measured in a bulk medium rather than merely at a surface. For this reason neutrons are used due to their high penetrating power in dense material. In addition, the mass attenuation coefficient for neutrons in hydrogen is significantly larger than for all other elements, meaning that neutrons have a higher probability of interacting with hydrogen than with other elements in the sample matrix. Neutrons have been used in the following areas: Fast Neutron Transmission, Scattering and Activation Technique; Digital Neutron Imaging; Hydrogen Detection by Epithermal Neutrons; Microscopic Behaviour of Hydrogen in Bulk Materials

  4. Use of functionalized surfactants in flame atomic analysis: Final technical report

    International Nuclear Information System (INIS)

    Research results in the following areas are briefly summarized: basic properties of surfactants, micelles, and cyclodextrins as they relate to chemical analysis; use of functionalized surfactants, micelles, and cyclodextrins in spectroscopic analysis; macromolecular separation theory and mechanism; use of functionalized surfactants and cyclodextrins in separations; capillary work for future coupling of spectroscopic and LC projects

  5. 77 FR 47495 - Final Priority; Technical Assistance on State Data Collection, Analysis, and Reporting-National...

    Science.gov (United States)

    2012-08-08

    ... State Data Collection, Analysis, and Reporting--National IDEA Technical Assistance Center on Early...; Technical Assistance on State Data Collection, Analysis, and Reporting--National IDEA Technical Assistance... (NPP) for this competition in the Federal Register on May 4, 2012 (77 FR 26522). That notice...

  6. Grid-connected ICES: preliminary feasibility analysis and evaluation. Volume 3. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-06-30

    Maps, charts, and drawings of the Demonstration Community for the grid-connected ICES project composed of the medical complex in New Orleans (HEAL) are presented in Appendix A. The physical profile of the existing buildings and site plans is included. Demand profiles for steam, electric, gas, etc. are presented in Appendix B with extensive tables and graphs. Air quality and noise pollution data are presented in Appendix C. Data on financing in Appendix D are presented and also texts and information on revenue bonds are given. The final appendix gives qualifications for personnel for HEAL; NOSPI; de Laureal Engineers, Inc.; and Orr-Schelen-Mayeron and Associates, Inc.

  7. 1988 Progress report of the EDF department for the analysis of experimental data and measurements

    International Nuclear Information System (INIS)

    The 1988 activity report of the department for the analysis of experimental data and measurements (Department of Retour d'Experience Mesures-Essais, of EDF, France), is presented. The mission of the department is to collect and investigate data from the nuclear power plant operations. The investigations started before 1988, were carried on in 1988. The department main activities are: technology and information transfer from experimental activities, the construction of a standard data acquisition and processing system, the actions involving the N4 turbine, and the modelling and construction of new non-destructive methods of control. The most important facts and activities carried out in 1988 are presented

  8. Development of an engineering analysis of progressive damage in composites during low velocity impact

    Science.gov (United States)

    Humphreys, E. A.

    1981-01-01

    A computerized, analytical methodology was developed to study damage accumulation during low velocity lateral impact of layered composite plates. The impact event was modeled as perfectly plastic with complete momentum transfer to the plate structure. A transient dynamic finite element approach was selected to predict the displacement time response of the plate structure. Composite ply and interlaminar stresses were computed at selected time intervals and subsequently evaluated to predict layer and interlaminar damage. The effects of damage on elemental stiffness were then incorporated back into the analysis for subsequent time steps. Damage predicted included fiber failure, matrix ply failure and interlaminar delamination.

  9. Progress in field-assisted extraction and its application to solid sample analysis.

    Science.gov (United States)

    He, Yuanyuan; Xiao, Xiaohua; Cheng, Yingyi; Li, Gongke

    2016-01-01

    Sample preparation is the most time-consuming and laborious procedure during analysis. The rapid and effective extraction of solid and semi-solid samples is much more difficult than that of gas and liquid samples. In the present review, various extraction methods for solid and semi-solid samples such as supercritical fluid extraction, ultrasound-assisted extraction, microwave-assisted extraction, etc. are summarized based on the principles of field and field synergy effects. The expected trends of field-assisted extraction methods are discussed and proposed to encourage further development on the rapid and effective extraction for solid and semi-solid samples. PMID:26390199

  10. SPECT-CT and PET-CT progress in the research of computer analysis method

    OpenAIRE

    Jingang Guo; Shuming Xu; Xiaoli Zhang; Hongyu Zhang

    2015-01-01

    The development of multimodal imaging equipment is milestone in the development of imaging, after the PET-CT, American GE company launched a Discovery 670 NM/CT, CT and SPECT, the organic integration of the formation of SPECT-CT new molecular medical imaging equipment, with SPECT, CT and PET-CT is getting more and more widely attention and application, many of SPECT-CT and PET-CT image analysis computer method arises at the historic moment, getting increasing attention of the clinical and ima...

  11. Research in progress in applied mathematics, numerical analysis, fluid mechanics, and computer science

    Science.gov (United States)

    1994-01-01

    This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, fluid mechanics, and computer science during the period October 1, 1993 through March 31, 1994. The major categories of the current ICASE research program are: (1) applied and numerical mathematics, including numerical analysis and algorithm development; (2) theoretical and computational research in fluid mechanics in selected areas of interest to LaRC, including acoustics and combustion; (3) experimental research in transition and turbulence and aerodynamics involving LaRC facilities and scientists; and (4) computer science.

  12. Organic Tanks Safety Program: Advanced organic analysis FY 1996 progress report

    International Nuclear Information System (INIS)

    Major focus during the first part of FY96 was to evaluate using organic functional group concentrations to screen for energetics. Fourier transform infrared and Raman spectroscopy would be useful screening tools for determining C-H and COO- organic content in tank wastes analyzed in a hot cell. These techniques would be used for identifying tanks of potential safety concern that may require further analysis. Samples from Tanks 241-C-106 and -C-204 were analyzed; the major organic in C-106 was B2EHPA and in C-204 was TBP. Analyses of simulated wastes were also performed for the Waste Aging Studies Task; organics formed as a result of degradation were identified, and the original starting components were monitored quantitatively. Sample analysis is not routine and required considerable methods adaptation and optimization. Several techniques have been evaluated for directly analyzing chelator and chelator fragments in tank wastes: matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and liquid chromatography with ultraviolet detection using Cu complexation. Although not directly funded by the Tanks Safety Program, the success of these techniques have implications for both the Flammable Gas and Organic Tanks Safety Programs

  13. Energy certification of buildings: A comparative analysis of progress towards implementation in European countries

    Energy Technology Data Exchange (ETDEWEB)

    Andaloro, Antonio P.F., E-mail: apfandaloro@unime.i [Dipartimento di Studi e Ricerche Economico-aziendali ed Ambientali, Universita degli Studi di Messina, Piazza Pugliatti, 1, 98122 Messina (Italy); Salomone, Roberta, E-mail: roberta.salomone@unime.i [Dipartimento di Studi e Ricerche Economico-aziendali ed Ambientali, Universita degli Studi di Messina, Piazza Pugliatti, 1, 98122 Messina (Italy); Ioppolo, Giuseppe, E-mail: giuseppe.ioppolo@unime.i [Dipartimento di Diritto dell' Economia, dei Trasporti e dell' Ambiente, Universita degli Studi di Palermo, Viale delle Scienze 28, 90128 Palermo (Italy); Andaloro, Laura, E-mail: andaloro@itae.cnr.i [Istituto di Tecnologie Avanzate per l' Energia ' Nicola Giordano' , ITAE-CNR, Via Salita Santa Lucia sopra Contesse 5, 98126 Messina (Italy)

    2010-10-15

    The Energy Performance Building Directive (Directive 2002/91/EC) introduced the compulsory energy certification of buildings in the EU from 2006 and it has played a key role in the common policy to monitor and reduce energy consumption. In order to assess the experience gained in this field in Europe overall, and in particular against the highly diverse settings of the different European nations, this paper examines the extent to which the Directive has been implemented by the 27 EU Member States. This is done via a comparative analysis assisted by two different indicators: of uniformity and of excellence. The measure of uniformity makes it possible to assess the degree of harmony of the individual Member States with regard to the parameters laid down by the European Commission, while the measure of excellence allows the Member States to be appraised and the 'best' performers to be identified, i.e. the leaders as regards energy certification of buildings. The analysis conducted reveals how varied the situation regarding energy certification in each country is in terms of implementation and scope of application and it also reveals that most countries are still at a halfway stage towards achieving excellence.

  14. Energy certification of buildings. A comparative analysis of progress towards implementation in European countries

    Energy Technology Data Exchange (ETDEWEB)

    Andaloro, Antonio P.F.; Salomone, Roberta [Dipartimento di Studi e Ricerche Economico-aziendali ed Ambientali, Universita degli Studi di Messina, Piazza Pugliatti, 1, 98122 Messina (Italy); Ioppolo, Giuseppe [Dipartimento di Diritto dell' Economia, dei Trasporti e dell' Ambiente, Universita degli Studi di Palermo, Viale delle Scienze 28, 90128 Palermo (Italy); Andaloro, Laura [Istituto di Tecnologie Avanzate per l' Energia ' Nicola Giordano' , ITAE - CNR, Via Salita Santa Lucia sopra Contesse 5, 98126 Messina (Italy)

    2010-10-15

    The Energy Performance Building Directive (Directive 2002/91/EC) introduced the compulsory energy certification of buildings in the EU from 2006 and it has played a key role in the common policy to monitor and reduce energy consumption. In order to assess the experience gained in this field in Europe overall, and in particular against the highly diverse settings of the different European nations, this paper examines the extent to which the Directive has been implemented by the 27 EU Member States. This is done via a comparative analysis assisted by two different indicators: of uniformity and of excellence. The measure of uniformity makes it possible to assess the degree of harmony of the individual Member States with regard to the parameters laid down by the European Commission, while the measure of excellence allows the Member States to be appraised and the 'best' performers to be identified, i.e. the leaders as regards energy certification of buildings. The analysis conducted reveals how varied the situation regarding energy certification in each country is in terms of implementation and scope of application and it also reveals that most countries are still at a halfway stage towards achieving excellence. (author)

  15. Energy certification of buildings: A comparative analysis of progress towards implementation in European countries

    International Nuclear Information System (INIS)

    The Energy Performance Building Directive (Directive 2002/91/EC) introduced the compulsory energy certification of buildings in the EU from 2006 and it has played a key role in the common policy to monitor and reduce energy consumption. In order to assess the experience gained in this field in Europe overall, and in particular against the highly diverse settings of the different European nations, this paper examines the extent to which the Directive has been implemented by the 27 EU Member States. This is done via a comparative analysis assisted by two different indicators: of uniformity and of excellence. The measure of uniformity makes it possible to assess the degree of harmony of the individual Member States with regard to the parameters laid down by the European Commission, while the measure of excellence allows the Member States to be appraised and the 'best' performers to be identified, i.e. the leaders as regards energy certification of buildings. The analysis conducted reveals how varied the situation regarding energy certification in each country is in terms of implementation and scope of application and it also reveals that most countries are still at a halfway stage towards achieving excellence.

  16. Organic Tanks Safety Program: Advanced organic analysis FY 1996 progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    Major focus during the first part of FY96 was to evaluate using organic functional group concentrations to screen for energetics. Fourier transform infrared and Raman spectroscopy would be useful screening tools for determining C-H and COO- organic content in tank wastes analyzed in a hot cell. These techniques would be used for identifying tanks of potential safety concern that may require further analysis. Samples from Tanks 241-C-106 and -C-204 were analyzed; the major organic in C-106 was B2EHPA and in C-204 was TBP. Analyses of simulated wastes were also performed for the Waste Aging Studies Task; organics formed as a result of degradation were identified, and the original starting components were monitored quantitatively. Sample analysis is not routine and required considerable methods adaptation and optimization. Several techniques have been evaluated for directly analyzing chelator and chelator fragments in tank wastes: matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and liquid chromatography with ultraviolet detection using Cu complexation. Although not directly funded by the Tanks Safety Program, the success of these techniques have implications for both the Flammable Gas and Organic Tanks Safety Programs.

  17. Literature analysis and research progress of the landscape ecology in China in the 1990s

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper makes analysis of published articles and books on landscape ecology in the 1990s through literature collection. The analytical results showed that the study of landscape ecology had made a great advance during the past decade in China. By incomplete survey, Chinese researchers at home and abroad published 619 scientific articles and 13 monographs on landscape ecology in the 1990s, and most of them (more than 90%) were published in Chinese with English abstracts. The published articles on basic theory accounted for 39.6% (245 articles), and those concerning application and methods accounted for 36.8% (228) and 23.6% (146), respectively. According to the objects of research, the published articles on landscape ecology were classified into nine catalogues. The urban landscape ranks first in terms of number of published articles, accounting for 13.4% of the total, followed by regional and river basin landscape, cold and arid landscape, forest landscape, habitat and bio-diversity landscape, agricultural landscape, wetlands, suburban landscape, and vegetation landscape. Based on the analysis, some discussions were made on the existing problems and development trend of landscape ecology study in China

  18. Development and analysis of fusion breeder blanket neutronics. Progress report, November 1, 1983-October 31, 1984

    International Nuclear Information System (INIS)

    The following activities are briefly described: (a) the IBM versions of the computer codes FORSS, PUFF-II, ONETRAN, TWOTRAN-II, and DOT4.3 were obtained from the Radiation Shielding Information Center (RSIC) and have been implemented on the UCLA local computer, the IBM 3033; (b) mathematical and computational models to describe the time-dependent transport and inventory of tritium in individual components of a fusion reactor system have been developed; (c) extensive cross-section sensitivity and uncertainty analysis was carried out to evaluate an estimate for the uncertainty associated with the TBR (both from 6Li and 7Li, individually) in four of the leading blanket concepts (the Li2O/HT-9 helium-cooled blanket, the 17Li-83Pb/PCA self-cooled blanket, the LiAlO2/He/FS/Be blanket, and the flibe/He/FS/Be blanket); (d) as far as the TBR obtain able in various blanket concepts is concerned, a comparative analysis was carried out to estimate the change in TBR in a particular blanket module when placed in a tokamak machine [R (first wall) approx. 2 m] as opposed to adopting the same blanket in a mirror machine [R (first wall) approx. 50 cm] with the same wall loading

  19. Challenges in Updating a Generic Safety Analysis Report after 22 Years of Technological and Regulatory Progress

    International Nuclear Information System (INIS)

    The original Safety Analysis Report (SAR) for the 20 kW (nominal) Ecole Polytechnique Safe Low Power Critical Experiment (SLOWPOKE) research reactor comprised a generic report produced in 1977. This SAR was applicable to all SLOWPOKE reactors constructed in the period 1971-1985. Since that period, IAEA international standards for SARs have changed and been developed into the IAEA's Safety Series No. 35-G1, Safety Assessment of Research Reactors and Preparation of the Safety Analysis Report, intended to be recommendations based on international experience. In addition, national licensing standards for research reactors have become more rigorous since the original generic SAR was produced. The original SLOWPOKE reactor was designed to operate for 20 years and was not intended to be refuelled. After 21 years of operation with the original HEU fuel core, it was planned to convert the Ecole Polytechnique reactor core to LEU fuel in order to extend the life of the reactor for another 30 years. Since this was the first SLOWPOKE reactor to be converted to LEU fuel, preparation of an updated and site-specific SAR was necessary to obtain authorization for refuelling. As part of the SAR update, an independent Operational Safety Review and a review of all safety related LEU refuelling documentation were also performed. (author)

  20. RESEARCH PROGRESS ON STRUCTURAL FATIGUE RELIABILITY DESIGN AND ANALYSIS METHODS OF CHINESE RAILWAY VEHICLES

    Institute of Scientific and Technical Information of China (English)

    ZHAO Yongxiang; PENG Jiachun; YANG Bing

    2007-01-01

    A state-of-art review is given to the new advances on fatigue reliability design and analysis methods of Chinese railway vehicle's structures. First, the structures are subject to a complicated random fatigue stressing history and this history should be determined by combining dynamic Simulation and on-line inspection. Second, the random fatigue constitutions belong to an intrinsic fatigue phenomenon and a probabilistic model is developed to well describe them with two measurements of survival probability and confidence, similar model is also presented for the random stress-life relations and extrapolated appropriately into long fatigue life regime. Third, concept of the fatigue limit should be understood as the fatigue strength at a given fatigue life and a so-called local Basquin model method is proposed for measuring the random strengths. In addition, drawing and application methods of the Goodman-Smith diagram for integrally characterizing the random fatigue strengths are established in terms of ten kilometers. Fourth, a reliability stress-based method is constructed with a consideration of the random constitutive relations. These new advances form a new frame work for railway fatigue reliability design and analysis.

  1. On the Partial-Wave Analysis of Mesonic Resonances Decaying to Multiparticle Final States Produced by Polarized Photons

    Energy Technology Data Exchange (ETDEWEB)

    Salgado, Carlos W. [Norfolk State University, Norfolk, VA (United States) and Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Weygand, Dennis P. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States)

    2014-04-01

    Meson spectroscopy is going through a revival with the advent of high statistics experiments and new advances in the theoretical predictions. The Constituent Quark Model (CQM) is finally being expanded considering more basic principles of field theory and using discrete calculations of Quantum Chromodynamics (lattice QCD). These new calculations are approaching predictive power for the spectrum of hadronic resonances and decay modes. It will be the task of the new experiments to extract the meson spectrum from the data and compare with those predictions. The goal of this report is to describe one particular technique for extracting resonance information from multiparticle final states. The technique described here, partial wave analysis based on the helicity formalism, has been used at Brookhaven National Laboratory (BNL) using pion beams, and Jefferson Laboratory (Jlab) using photon beams. In particular this report broaden this technique to include production experiments using linearly polarized real photons or quasi-real photons. This article is of a didactical nature. We describe the process of analysis, detailing assumptions and formalisms, and is directed towards people interested in starting partial wave analysis.

  2. On the partial-wave analysis of mesonic resonances decaying to multiparticle final states produced by polarized photons

    Energy Technology Data Exchange (ETDEWEB)

    Salgado, Carlos W., E-mail: salgado@jlab.org [Norfolk State University (United States); The Thomas Jefferson National Accelerator Facility (United States); Weygand, Dennis P. [The Thomas Jefferson National Accelerator Facility (United States)

    2014-04-01

    Meson spectroscopy is going through a revival with the advent of high statistics experiments and new advances in the theoretical predictions. The Constituent Quark Model (CQM) is finally being expanded considering more basic principles of field theory and using discrete calculations of Quantum Chromodynamics (lattice QCD). These new calculations are approaching predictive power for the spectrum of hadronic resonances and decay modes. It will be the task of the new experiments to extract the meson spectrum from the data and compare with those predictions. The goal of this report is to describe one particular technique for extracting resonance information from multiparticle final states. The technique described here, partial wave analysis based on the helicity formalism, has been used at Brookhaven National Laboratory (BNL) using pion beams, and Jefferson Laboratory (JLab) using photon beams. In particular this report broadens this technique to include production experiments using linearly polarized real photons or quasi-real photons. This article is of a didactical nature. We describe the process of analysis, detailing assumptions and formalisms, and is directed towards people interested in starting partial wave analysis.

  3. Areas of progress towards a factor 4 territorial coherence scheme. Which local levers for a post-carbon conurbation? Final report - Scenario 2020-2030

    International Nuclear Information System (INIS)

    Taking the Tours conurbation as an example, this study examines how to elaborate and define a new territorial coherence scheme (a land and urban planning tool) which would include a planned reduction of greenhouse gas emissions by a factor 4 between 2020 and 2030. It is therefore a prospective study with 2006 as a reference year (reductions are assessed with respect to 2006 due to data availability). After an analysis of the reference situation (2006) and of objectives, the report presents the scenario for 2020-2030, analyses the various levers in different sectors (mobility, housing, office building, industry and construction, agriculture), and examines possibilities related to the production of renewable energy, the adaptation to climate change, the creation of a new governance to mitigate and to adapt to climate change. Expected gains are discussed for transports, housing, office building, industry, agriculture, renewable energies, and adaptation. The last part reports a sensitive approach to a post-carbon world through different workshops (with children or within a fiction writing workshop)

  4. Analysis of ex situ processes of CO2 sequestration. Final report

    International Nuclear Information System (INIS)

    The aim of this study is to bring quantitative elements to evaluate the validation of the CO2 mineral sequestration to limit the greenhouse effect gases. This analysis aims to calculate the CO2 accounting of the system (internal energy production balance the energy expend) sequestrated CO2 and produced CO2. The first part detailed the possible experimental solutions. Then two carbonation processes, direct and indirect, have been chosen of the analysis. (A.L.B.)

  5. THE ECONOMIC ANALYSIS OF LAW - WILL THE ROMANIAN DOCTRINE FINALLY CATCH UP WITH IT?

    OpenAIRE

    MONICA-FLORENTINA POPA

    2013-01-01

    Although a well-established presence on the international legal scene, the economic analysis of law is still an unfamiliar concept to most Romanian scholars. While worldwide, prestigious universities offer special courses on this topic and an impressive body of legal studies continues to add up, only scant traces of this important legal school can be detected in some recent Romanian doctoral thesis and papers. This article explores the main concepts of the economic analysis of law, the recent...

  6. Next Generation Electromagnetic Pump Analysis Tools (PLM DOC-0005-2188). Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Stregy, Seth [GE Hitachi Nuclear Energy Americas LLC, Wilmington, NC (United States); Dasilva, Ana [GE Hitachi Nuclear Energy Americas LLC, Wilmington, NC (United States); Yilmaz, Serkan [GE Hitachi Nuclear Energy Americas LLC, Wilmington, NC (United States); Saha, Pradip [GE Hitachi Nuclear Energy Americas LLC, Wilmington, NC (United States); Loewen, Eric [GE Hitachi Nuclear Energy Americas LLC, Wilmington, NC (United States)

    2015-10-29

    This report provides the broad historical review of EM Pump development and details of MATRIX development under this project. This report summarizes the efforts made to modernize the legacy performance models used in previous EM Pump designs and the improvements made to the analysis tools. This report provides information on Tasks 1, 3, and 4 of the entire project. The research for Task 4 builds upon Task 1: Update EM Pump Databank and Task 3: Modernize the Existing EM Pump Analysis Model, which are summarized within this report. Where research for Task 2: Insulation Materials Development and Evaluation identified parameters applicable to the analysis model with Task 4, the analysis code was updated, and analyses were made for additional materials. The important design variables for the manufacture and operation of an EM Pump that the model improvement can evaluate are: space constraints; voltage capability of insulation system; maximum flux density through iron; flow rate and outlet pressure; efficiency and manufacturability. The development of the next-generation EM Pump analysis tools during this two-year program provides information in three broad areas: Status of analysis model development; Improvements made to older simulations; and Comparison to experimental data.

  7. Using a profiling process to insure program quality: Volume II - support materials. Final progress report, May 15, 1991--November 14, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Kaser, J.S.; Roody, D.S.; Raizen, S.A.

    1996-11-01

    Between 1990 and 1995 the U.S. Department of Energy (DOE) and the National Center for Improving Science Education (National Center) developed a system for ongoing evaluation of K-12 educational programs in the DOE-supported national energy Laboratories. As part of the formative evaluation component of this collaborative endeavor, field staff in the Laboratories began creating profiles of their programs. However, many individuals within DOE Headquarters were not familiar with this profiling process and were unprepared to use the valuable information that the profiles generated. This manual was produced to orient Headquarters staff to profiling. It focuses on how Headquarters staff can use the profiling process to help their funded programs establish and/or maintain high quality. Its purpose, then, is not to train Headquarters staff to become proficient in profiling, but to show them how to draw on the Laboratories` use of profiling to bring about program improvement. Profiling is the process of systematically examining and describing a program`s elements against a set of components that define Effective Practice. The instrument used to capture the data for analysis is called a template, and most of this manual focuses on the templates and how to read and interpret them. However, since it is important to understand these data in context, the authors also describe what should accompany each template in a complete profiling packet and offer guidelines for reviewing complete packets and providing feedback to program managers. This document consists of Support Materials for the manual: exercise answer keys; templates; guidelines for reviewing templates; a complete profiling packet; guidelines for the trainer.

  8. Progress in the pellet charge exchange diagnostics on LHD and local neutral particle spectra analysis

    International Nuclear Information System (INIS)

    Production, confinement and thermalization of high-energy particles are the fundamental issues in fusion plasma ion kinetics. The ion distribution function ft(ν, θ, t) and its evolution under the ion cyclotron heating (ICH) and neutral beam injection (NBI) are studied by energy resolved charge exchange neutral particle flux measurements. For helical systems, such as LHD, local diagnostics are required due to the complex 3D magnetic configuration. First radially resolved measurements of local H0 atomic energy spectra have been made on LHD by the pellet charge exchange (PCX) method with a Compact Neutral Particle Analyzer (CNPA). The diagnostic technique, the initial measurement results in the range 10-100 keV and the data analysis are described. (author)

  9. Systems analysis and testing (SAT) program. Progress report, October 1, 1978--March 31, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Bishop, C.J.

    1979-07-01

    This document describes SERI activities for the SAT program during 1 October 1978-31 March 1979. These include (1) a reevaluation of thermosiphon hot water systems; (2) a review of existing wind machine performance models; a study of the effects of wind transients, and control system and load management on energy capture; (3) a study of new concepts for solar ponds involving stratified ponds; (4) establishment of the SERI Computational Methods Center; (5) dissemination of F-chart; (6) a review of photovoltaic systems analysis methods; (7) development of a draft SAT Program Plan, SAT Management Plan, and an integrated System Test and Validation Plan; and (8) transfer of technical management of DOE contracts in the SAT program.

  10. Progress in Root Cause and Fault Propagation Analysis of Large-Scale Industrial Processes

    Directory of Open Access Journals (Sweden)

    Fan Yang

    2012-01-01

    Full Text Available In large-scale industrial processes, a fault can easily propagate between process units due to the interconnections of material and information flows. Thus the problem of fault detection and isolation for these processes is more concerned about the root cause and fault propagation before applying quantitative methods in local models. Process topology and causality, as the key features of the process description, need to be captured from process knowledge and process data. The modelling methods from these two aspects are overviewed in this paper. From process knowledge, structural equation modelling, various causal graphs, rule-based models, and ontological models are summarized. From process data, cross-correlation analysis, Granger causality and its extensions, frequency domain methods, information-theoretical methods, and Bayesian nets are introduced. Based on these models, inference methods are discussed to find root causes and fault propagation paths under abnormal situations. Some future work is proposed in the end.

  11. Recent progress in quantitative analysis of DNA adducts of nephrotoxin aristolochic acid

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Aristolochic acid (AA), a mixture of structure-related nitrophenanthrene carboxylic acid derivatives derived from Aristolochia spp, is associated with nephrotoxin and carcinogen. AA-DNA adducts induced by reductive metabolic activation of AA were detected in tissues of animals and in patients exposed to AA. The DNA adducts were generally used as biomarkers in toxicological study of AA. In this short review, quantitative analysis of AA-DNA adducts in various in vitro and in vivo systems by using 32P-postlabelling assay, HPLC-UV, HPLC-radiation monitor, HPLC-FLD, HPLC-ESI/MS and UPLC-MS/MS methods is discussed. The distribution of AA-DNA adducts in various tissues is also summarized.

  12. Progress in postirradiation examination and analysis of low-enriched U-Mo research reactor fuels

    International Nuclear Information System (INIS)

    High-density dispersion fuel experiment, RERTR-4, was removed from the Advanced Test Reactor (ATR) after reaching a peak U-235 burnup of ∼80% and is presently undergoing postirradiation examination at the ANL Alpha-Gamma Hot Cell Facility. This test consists of 32 mini fuel plates of which 27 were fabricated with nominally 6 and 8 g cm-3 atomized and machined uranium alloy powders containing 6.5 wt% to 10 wt% molybdenum. In addition, two miniplates containing solid U-10wt% Mo foils. The results of the postirradiation examination and analysis of RERTR-4 in conjunction with data from a companion test performed to 50% burnup, RERTR-5, are presented. (author)

  13. Damage analysis and fundamental studies. Quarterly progress report, January-March 1980

    Energy Technology Data Exchange (ETDEWEB)

    1980-05-01

    The DAFS program element is a national effort composed of contributions from a number of National Laboratories and other government laboratories, universities, and industrial laboratories. It was organized by the Materials and Radiation Effects Branch, Office of Fusion Energy, DOE, and a Task Group on Damage Analysis and Fundamental Studies which operates under the auspices of that Branch. The purpose of this series of reports is to provide a working technical record of that effort for the use of the program participants, for the fusion energy program in general, and for the Department of Energy. This report is organized along topical lines in parallel to a Program Plan of the same title so that activities and accomplishments may be followed readily, relative to that Program Plan. Thus, the work of a given laboratory may appear throughout the report. The Table of Contents is annotated for the convenience of the reader.

  14. Post-Buckling and Ultimate Strength Analysis of Stiffened Composite Panel Base on Progressive Damage

    Science.gov (United States)

    Zhang, Guofan; Sun, Xiasheng; Sun, Zhonglei

    Stiffened composite panel is the typical thin wall structure applied in aerospace industry, and its main failure mode is buckling subjected to compressive loading. In this paper, the development of an analysis approach using Finite Element Method on post-buckling behavior of stiffened composite structures under compression was presented. Then, the numerical results of stiffened panel are obtained by FE simulations. A thorough comparison were accomplished by comparing the load carrying capacity and key position strains of the specimen with test. The comparison indicates that the FEM results which adopted developed methodology could meet the demand of engineering application in predicting the post-buckling behavior of intact stiffened structures in aircraft design stage.

  15. Progress report on development of intermediate fidelity full assembly analysis methods.

    Energy Technology Data Exchange (ETDEWEB)

    Hu, R.; Fanning, T. H. (Nuclear Engineering Division)

    2011-09-30

    While high fidelity modeling capabilities for various physics phenomena are being pursued under advanced modeling and simulation initiatives under the DOE Office of Nuclear Energy, they generally rely on high-performance computation facilities and are too expensive to be used for parameter-space exploration or design analysis. One-dimensional system codes have been used for a long time and have reached a degree of maturity, but limit their validity to specific applications. Thus, an intermediate fidelity (IF) modeling method is being pursued in this work for a fast-running, modest-fidelity, whole-core transient analyses capability. The new approach is essential for design scoping and engineering analyses and could lead to improvements in the design of the new generations of reactors and to the reduction of uncertainties in safety analysis. This report summarizes the initial effort on the development of the intermediate-fidelity full assembly modeling method. The requirements and the desired merits of the IF approach have been defined. A three-dimensional momentum source model has been developed to model the anisotropic flow in the wire-wrapped rod bundle without the need to resolve the geometric details. It has been confirmed that the momentum source model works well if its affecting region is accurately imposed. The validity of the model is further verified by mesh and parameter sensitivity studies. The developed momentum source model, in principle, can be applied to any wire-wrapped bundle geometries and any flow regimes; while the modeling strategy can be applied to other conditions with complex or distorted geometry, such as flow in blocked channels.

  16. Trend analysis report on energy consumptions and savings in France in 2012 and 2013: final report

    International Nuclear Information System (INIS)

    This report presents and comments a large set of data regarding CO2 and energy savings recorded in France since 1990 with a focus on the 2008-2012 period which has been marked by a financial and economic crisis which had a strong impact on energy demand. In its first part, the report presents the French economic and energetic context since 1990 with a focus on years between 2008 and 2013. It is based on the last available energy assessments published by the French Ministry of Ecology, Sustainable Development and Energy and addresses the following issues: a fragile economic context, relatively high energy prices, a decrease of final energy consumption since 2010, and a reduction of industry energy intensity. The second part addresses CO2 and energy savings generated by France between 1990 and 2012, with a focus on recent years: overview of the evolutions in the industrial sector, in the transport sector, and in the building sector (existing buildings)

  17. Consumer demand analysis: solar heating and cooling of buildings. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Scott, J.E.

    1976-09-01

    This study concerns the acceptability of solar heating and cooling to homebuyers for residential applications. The study assesses the extent of homeowner awareness of solar technologies, estimates the acceptability of elevated first costs including willingness to trade higher initial costs for life cycle savings, and investigates the impact of solar aesthetics. Also explored are other areas of potential concern to homeowners in evaluating a solar alternative as well as positive motivations that would encourage purchase. Finally, the socioeconomic and attitudinal characteristics of individuals more likely to purchase a solar home rather than a conventional home were studied. The results are based on group depth interviews and personal interviews with active homeseekers, top executives of large residential development firms, and architects. The sample was split evenly between Denver, Colorado and the Philadelphia, Pa./Wilmington, Del. areas. Implications of the results for the commercialization of solar energy and possible public policy decisions are also discussed.

  18. Portraits of breast cancer progression

    Directory of Open Access Journals (Sweden)

    Ganesan Shridar

    2007-08-01

    Full Text Available Abstract Background Clustering analysis of microarray data is often criticized for giving ambiguous results because of sensitivity to data perturbation or clustering techniques used. In this paper, we describe a new method based on principal component analysis and ensemble consensus clustering that avoids these problems. Results We illustrate the method on a public microarray dataset from 36 breast cancer patients of whom 31 were diagnosed with at least two of three pathological stages of disease (atypical ductal hyperplasia (ADH, ductal carcinoma in situ (DCIS and invasive ductal carcinoma (IDC. Our method identifies an optimum set of genes and divides the samples into stable clusters which correlate with clinical classification into Luminal, Basal-like and Her2+ subtypes. Our analysis reveals a hierarchical portrait of breast cancer progression and identifies genes and pathways for each stage, grade and subtype. An intriguing observation is that the disease phenotype is distinguishable in ADH and progresses along distinct pathways for each subtype. The genetic signature for disease heterogeneity across subtypes is greater than the heterogeneity of progression from DCIS to IDC within a subtype, suggesting that the disease subtypes have distinct progression pathways. Our method identifies six disease subtype and one normal clusters. The first split separates the normal samples from the cancer samples. Next, the cancer cluster splits into low grade (pathological grades 1 and 2 and high grade (pathological grades 2 and 3 while the normal cluster is unchanged. Further, the low grade cluster splits into two subclusters and the high grade cluster into four. The final six disease clusters are mapped into one Luminal A, three Luminal B, one Basal-like and one Her2+. Conclusion We confirm that the cancer phenotype can be identified in early stage because the genes altered in this stage progressively alter further as the disease progresses through DCIS

  19. Stiffness and progressive damage analysis on random chopped fiber composite using FEM

    Science.gov (United States)

    Pan, Yi

    The need of vehicle weight reduction and fuel efficiency in the automotive industry calls for substituting traditional materials with lightweight ones. With the maturity of the preforming technologies, random chopped fiber composites have received increasing attention in recent years as replacement for traditional structural materials. In order to expand their application, accurate material characterization is required. Material properties such as effective elastic stiffness, material damage behavior, and strength are of primary interest. In this thesis, a micro-mechanics based finite element analysis method for the random chopped fiber composite is developed. In order to obtain the effective material properties of random chopped fiber composites, a modified random sequential adsorption technique is proposed to generate the representative volume element of random chopped fiber composites. In the three-dimensional representative volume element generation algorithm, a fiber is bended locally to avoid intersecting other fibers and consequently to overcome the "jamming limit" in the existing techniques. The volume fraction of a representative volume element generated by the modified random sequential adsorption is as high as that of the specimens provided by industry, which is about 35% to 40%. A homogenization scheme is applied to the finite element solution of the boundary value problem, defined in the representative volume element with proper boundary conditions, to compute the effective elastic stiffness constants of the composite. An automatic procedure based on a moving window technique is also presented to determine the proper size of the representative volume element of the random chopped fiber composite. Investigation on the damage behavior of the composite is carried out by using constituent's mechanical properties. Three damage mechanisms are considered, namely, the matrix cracking, interfacial debonding, and fiber breakage. The cohesive zone model is

  20. The Pattern of Thematic Progression of Narrative Texts——the analysis of The woman on the hilltop

    Institute of Scientific and Technical Information of China (English)

    陈原艳

    2010-01-01

    In this paper,we take the story"The Woman on the Hilltop"as the corpus and one of the methods of discourse analysis(thematic distribution)of systemic-functional grammar as a means to explore the pattern of thematic progression of Narrative Texts.Conclusion:the communicative purpose of narrative genre is to tell the others what happened to someone.In this case,human as the main theme of the texts of this kind becomes one of the most prominent features.From the perspective of thematic progression,it belongs to the pattern of the same theme,specifically,themes are same,themes are different.%本文以故事为语料,以系统功能语法中对语篇进行分析的方法之一(主位分布)为手段,探讨了叙事语篇的主位推进模式.结论是:叙事语篇体裁的交际目的是向对方讲述发生在某人身上的事情,这一交际目的使有生命的人充当语篇的主要主位成为这类语篇体裁的一个最为突出的特征,就主位推进模式而言,是主位同一型,具体地说就是主位相同,述位不同.

  1. Progress and Prospect: A Bibliometric Analysis of Research Papers by Korean Allergists Over Recent Five Years (2009-2013).

    Science.gov (United States)

    Song, Woo Jung; Jee, Hye Mi; Suh, Dong In; Yang, Hyeon Jong; Yoon, Jong Seo; Yu, Jinho; Kim, Sang Heon; Ye, Young Min; Kim, Tae Bum; Shin, Seung Youp; Li, Kapsok; Kim, Cheol Woo

    2015-09-01

    Since the establishment of the academic society in 1972, Korean allergists have made continuous efforts to elucidate pathogenic mechanisms and therapeutic advances for allergic diseases. The present study aimed to summarize recent progress and explore future prospects of research performance by Korean allergists. We performed a comprehensive bibliometric analysis for research papers published in the Science Citation Index (SCI) or SCI-expanded journals by Korean allergists between 2009 and 2013. Research performance was quantitatively analyzed for the numbers of papers by publication year, research type, and main topic. In addition, the performance was also examined for qualitative indices, such as impact factor and citation number. A total of 1,091 papers were identified. The number of publication increased continuously, with an annual increase rate of 12.3%. Clinical and basic studies were the most frequent types of research, and recently the number of epidemiological studies has increased. By research topic, asthma was the most commonly studied, accounting for 20.9% of the total number of publications. Notably, the amount of rhinitis/rhinosinusitis research has risen steeply in 2013. Qualitative analyses also indicated continuous progress; the median impact factor of published journals increased from 1.918 in 2009 to 2.746 in 2013, yielding an annual increase rate of 7.4%. In conclusion, the present analyses identified a continuous increase in the research performance of Korean allergists over a recent 5 year period (2009-2013), both quantitatively and qualitatively. A more significant contribution is expected in the forthcoming era. PMID:26122510

  2. Powerplant productivity improvement study: policy analysis and incentive assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-05-01

    Policy options that the Illinois Commerce Commission might adopt in order to promote improved power plant productivity for existing units in Illinois are identified and analyzed. These policy options would generally involve either removing existing disincentives and/or adding direct incentives through the regulatory process. The following activities are reported: in-depth review of existing theoretical and empirical literature in the areas of power plant reliability, regulatory utility efficiency and performance incentives, and impacts of various regulatory mechanisms such as the Fuel Adjustment Clauses on productivity; contacts with other state public utility commissions known to be investigating or implementing productivity improvement incentive mechanisms; documentation and analysis of incentive mechanisms adopted or under consideration in other states; analysis of current regulatory practice in Illinois as it relates to power plant productivity incentives and disincentives; identification of candidate incentive mechanisms for consideration by the Illinois Commerce Commission; and analysis and evaluation of these candidates. 72 references, 8 figures.

  3. 我国GAP分析的研究进展%Research Progress of GAP Analysis in China

    Institute of Scientific and Technical Information of China (English)

    郑岩岩; 刘吉平; 高俊琴

    2011-01-01

    This paper reviews the reasons and meaning of GAP analysis, and then summarizes the basic steps and process of typical GAP anal ysis, as well as its research area, research subject, research scale and research methods in China, at last presents the existing problems and future development tendency of the GAP analysis in China according to its research progress in foreign countries.%综述了GAP分析提出的原因及其涵义,总结了具有代表性的GAP分析的基本步骤和简单流程,归纳了我国GAP分析的研究区域、研究对象和研究尺度,介绍了我国GAP分析的研究方法,并针对国外GAP分析的研究进展,提出我国GAP分析的研究现状中目前存在的问题及未来发展的趋势.

  4. Further Progress Applying the Generalized Wigner Distribution to Analysis of Vicinal Surfaces

    Science.gov (United States)

    Einstein, T. L.; Richards, Howard L.; Cohen, S. D.

    2001-03-01

    Terrace width distributions (TWDs) can be well fit by the generalized Wigner distribution (GWD), generally better than by conventional Gaussians, and thus offers a convenient way to estimate the dimensionless elastic repulsion strength tildeA from σ^2, the TWD variance.(T.L. Einstein and O. Pierre-Louis, Surface Sci. 424), L299 (1999) The GWD σ^2 accurately reproduces values for the two exactly soluble cases at small tildeA and in the asymptotic limit. Taxing numerical simulations show that the GWD σ^2 interpolates well between these limits. Extensive applications have been made to experimental data, esp. on Cu.(M. Giesen and T.L. Einstein, Surface Sci. 449), 191 (2000) Recommended analysis procedures are catalogued.(H.L. Richards, S.D. Cohen, TLE, & M. Giesen, Surf Sci 453), 59 (2000) Extensions of the GWD for multistep distributions are tested, with good agreement for second-neighbor distributions, less good for third.(TLE, HLR, SDC, & OP-L, Proc ISSI-PDSC2000, cond-mat/0012xxxxx) Alternatively, step-step correlation functions, about which there is more theoretical information, should be measured.

  5. Analysis of accident progression in the TEPCO Fukushima Daiichi Nuclear Power Station

    International Nuclear Information System (INIS)

    One of the objectives of this study is to investigate the early stage of the TEPCO Fukushima Daiichi accident and to check the validity of the countermeasures against the accident. Last year the early stage of the accident was analyzed with use of RELAP5 code, and the longer term analysis was done by MELCOR code. This year, the simulation of reactor water level instrumentation behavior by MELCOR code was performed. Another objective of this study is to analyze of the long term cooling after the Fukushima Daiichi accident by TRACE5 code. In order to simulate the cooling conditions in Fukushima plants after the accident, the parametric calculations were done on the assumption of the existence of steam/liquid leak in Reactor Pressure Vessel (RPV) and Pressure Containment Vessel (PCV) and the variety of debris distribution in RPV and PCV. As a result, the debris distribution in RPV and PCV was estimated by referring plant parameter such as reactor pressure and temperature. (author)

  6. Advanced organic analysis and analytical methods development: FY 1995 progress report. Waste Tank Organic Safety Program

    Energy Technology Data Exchange (ETDEWEB)

    Wahl, K.L.; Campbell, J.A.; Clauss, S.A. [and others

    1995-09-01

    This report describes the work performed during FY 1995 by Pacific Northwest Laboratory in developing and optimizing analysis techniques for identifying organics present in Hanford waste tanks. The main focus was to provide a means for rapidly obtaining the most useful information concerning the organics present in tank waste, with minimal sample handling and with minimal waste generation. One major focus has been to optimize analytical methods for organic speciation. Select methods, such as atmospheric pressure chemical ionization mass spectrometry and matrix-assisted laser desorption/ionization mass spectrometry, were developed to increase the speciation capabilities, while minimizing sample handling. A capillary electrophoresis method was developed to improve separation capabilities while minimizing additional waste generation. In addition, considerable emphasis has been placed on developing a rapid screening tool, based on Raman and infrared spectroscopy, for determining organic functional group content when complete organic speciation is not required. This capability would allow for a cost-effective means to screen the waste tanks to identify tanks that require more specialized and complete organic speciation to determine tank safety.

  7. Advanced organic analysis and analytical methods development: FY 1995 progress report. Waste Tank Organic Safety Program

    International Nuclear Information System (INIS)

    This report describes the work performed during FY 1995 by Pacific Northwest Laboratory in developing and optimizing analysis techniques for identifying organics present in Hanford waste tanks. The main focus was to provide a means for rapidly obtaining the most useful information concerning the organics present in tank waste, with minimal sample handling and with minimal waste generation. One major focus has been to optimize analytical methods for organic speciation. Select methods, such as atmospheric pressure chemical ionization mass spectrometry and matrix-assisted laser desorption/ionization mass spectrometry, were developed to increase the speciation capabilities, while minimizing sample handling. A capillary electrophoresis method was developed to improve separation capabilities while minimizing additional waste generation. In addition, considerable emphasis has been placed on developing a rapid screening tool, based on Raman and infrared spectroscopy, for determining organic functional group content when complete organic speciation is not required. This capability would allow for a cost-effective means to screen the waste tanks to identify tanks that require more specialized and complete organic speciation to determine tank safety

  8. PV value analysis: Progress report on PV-Compact Coordinating Council's consensus research agenda

    International Nuclear Information System (INIS)

    A survey of published and ongoing valuation research indicates that grid-connected photovoltaic (PV) technology is at or close to cost-effectiveness, from the utility or end-user point of view, in an increasing but carefully selected array of distributed utility applications. This conclusion is based on conventional analyses of utility avoided costs (energy, effective load carrying capability, and transmission and distribution costs including line losses) and customer benefits (energy and demand bill savings, tax benefits). It may provide the basis for regulatory review of utility transmission or distribution investments to test prudence or usefulness. The conclusion would be stronger with consideration of the values of risk mitigation, power quality, strategic value to utilities, and satisfaction of customer preference. Further work would therefore be useful in quantifying these factors. The economic conclusions prevail irrespective of the structure of the utility industry. However, the analysis is site-specific so its broad application depends on development of easily operated models and other analytical tools for use in the field and by the regulatory process

  9. Temporal Progression of Pneumonic Plague in Blood of Nonhuman Primate: A Transcriptomic Analysis.

    Directory of Open Access Journals (Sweden)

    Rasha Hammamieh

    Full Text Available Early identification of impending illness during widespread exposure to a pathogenic agent offers a potential means to initiate treatment during a timeframe when it would be most likely to be effective and has the potential to identify novel therapeutic strategies. The latter could be critical, especially as antibiotic resistance is becoming widespread. In order to examine pre-symptomatic illness, African green monkeys were challenged intranasally with aerosolized Yersinia pestis strain CO92 and blood samples were collected in short intervals from 45 m till 42 h post-exposure. Presenting one of the first genomic investigations of a NHP model challenged by pneumonic plague, whole genome analysis was annotated in silico and validated by qPCR assay. Transcriptomic profiles of blood showed early perturbation with the number of differentially expressed genes increasing until 24 h. By then, Y. pestis had paralyzed the host defense, as suggested by the functional analyses. Early activation of the apoptotic networks possibly facilitated the pathogen to overwhelm the defense mechanisms, despite the activation of the pro-inflammatory mechanism, toll-like receptors and microtubules at the port-of-entry. The overexpressed transcripts encoding an early pro-inflammatory response particularly manifested in active lymphocytes and ubiquitin networks were a potential deviation from the rodent models, which needs further verification. In summary, the present study recognized a pattern of Y. pestis pathogenesis potentially more applicable to the human system. Independent validation using the complementary omics approach with comprehensive evaluation of the organs, such as lungs which showed early bacterial infection, is essential.

  10. Final Report: LSAC Skills Analysis. Law School Task Survey. LSAC Research Report Series.

    Science.gov (United States)

    Luebke, Stephen W.; Swygert, Kimberly A.; McLeod, Lori D.; Dalessandro, Susan P.; Roussos, Louis A.

    The Law School Admission Council (LSAC) Skills Analysis Survey identifies the skills that are important for success in law school. This information provides validity evidence for the current Law School Admission Test (LSAT) and guides the development of new test items and test specifications. The key question of the survey is "what academic tasks…

  11. Digital Avionics Information System (DAIS): Training Requirements Analysis Model Users Guide. Final Report.

    Science.gov (United States)

    Czuchry, Andrew J.; And Others

    This user's guide describes the functions, logical operations and subroutines, input data requirements, and available outputs of the Training Requirements Analysis Model (TRAMOD), a computerized analytical life cycle cost modeling system for use in the early stages of system design. Operable in a stand-alone mode, TRAMOD can be used for the…

  12. Development of On-Board Fluid Analysis for the Mining Industry - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Pardini, Allan F.

    2005-08-16

    Pacific Northwest National Laboratory (PNNL: Operated by Battelle Memorial Institute for the Department of Energy) is working with the Department of Energy (DOE) to develop technology for the US mining industry. PNNL was awarded a three-year program to develop automated on-board/in-line or on-site oil analysis for the mining industry.

  13. Grid-connected ICES: preliminary feasibility analysis and evaluation. Volume 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1977-06-30

    The HEAL Complex in New Orleans will serve as a Demonstration Community for which the ICES Demonstration System will be designed. The complex is a group of hospitals, clinics, research facilities, and medical educational facilities. The five tasks reported on are: preliminary energy analysis; preliminary institutional assessment; conceptual design; firming-up of commitments; and detailed work management plan.

  14. Discourse Analysis of Japanese and Thai. Part I: Thai Discourse. Final Report.

    Science.gov (United States)

    Jones, Robert B.; Jorden, Eleanor H.

    The Thai Discourse Analysis Project seeks to provide a description of linguistic structures of importance in understanding the nature of Thai speech. Previous studies have been limited, and restricted to consideration of the written language and "literary" speech. The project consists of three phases: the acquisition of recorded texts,…

  15. Supply-demand analysis. Volume II. of the offshore oil industry support craft market. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Durfee, J.H.

    1977-10-01

    Volume Two of this report presents a description of the market for offshore petroleum industry support craft and an analysis of that market. Financial performance of five major operating companies is described. A forecast of support craft supply and demand for 1977, 1982, and 1987 is included.

  16. Analysis and comparison of biomass pyrolysis/gasification condensates: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, D.C.

    1986-06-01

    This report provides results of chemical and physical analysis of condensates from eleven biomass gasification and pyrolysis systems. The samples were representative of the various reactor configurations being researched within the Department of Energy, Biomass Thermochemical Conversion program. The condensates included tar phases and aqueous phases. The analyses included gross compositional analysis (elemental analysis, ash, moisture), physical characterization (pour point, viscosity, density, heat of combustion, distillation), specific chemical analysis (gas chromatography/mass spectrometry, infrared spectrophotometry, proton and carbon-13 nuclear magnetic resonance spectrometry) and biological activity (Ames assay and mouse skin tumorigenicity tests). These results are the first step of a longer term program to determine the properties, handling requirements, and utility of the condensates recovered from biomass gasification and pyrolysis. The analytical data demonstrates the wide range of chemical composition of the organics recovered in the condensates and suggests a direct relationship between operating temperature and chemical composition of the condensates. A continuous pathway of thermal degradation of the tar components as a function of temperature is proposed. Variations in the chemical composition of the organic components in the tars are reflected in the physical properties of tars and phase stability in relation to water in the condensate. The biological activity appears to be limited to the tars produced at high temperatures. 56 refs., 25 figs., 21 tabs.

  17. Operations research and systems analysis of geopressured/geothermal resources in Texas. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lesso, W.G.; Zinn, C.D.; Cornwell, J.

    1981-05-01

    A preliminary resource assessment, based on the best available parameters, was made to identify potentially suitable fairways. Of those examined only the Brazoria Fairway in the Frio Formation was able to produce sufficient fluid to meet the minimum requirements. These requirements are based upon the need for a well to produce an initial flow rate of 40,000 bbl/day with a 6% decline rate over a 30 year production period. Next, a development planning analysis was done to determine the number of wells that would have to be drilled in the fairway, considering the probability of success, and the number of drilling rigs available. The results of this analysis provided a time phased scenario and costs of developing the fairway. These were next used in an economic analysis. The economic analysis was performed to determine the present worth of using the resource under a range of values for the key economic parameters. The results of this study indicate that the commercial development of geopressured, geothermal resource is highly dependent upon the pricing of natural gas in the US, the development of tax incentives to spur development, and a better understanding of the nature of the resource through additional well tests.

  18. Final report on the intercomparison of trace multielement analysis in fish solubles (A-6)

    International Nuclear Information System (INIS)

    The intercomparisons described in this report were organized during the first half of 1974. The purpose was to offer to laboratories dealing with trace element analysis in biological materials an opportunity to check their analytical performance. Verification of accuracy and determination of systematic errors was also possible in some cases

  19. Operations research and systems analysis of geopressured/geothermal resources in Louisiana. Final report for initiation project

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, B. Jr.

    1978-02-01

    The development activities for a plan for Louisiana's participation in a Gulf Coast regional research and systems analysis activity. In developing preliminary planning scenarios heavy emphasis was placed on data describing the resource base. The scenarios are produced using a computer-oriented planning program that is code-named GEODEV. Examples of development scenarios for four fairways in Louisiana are included in an appendix. Progress in identification of decision makers, a state-wide advisory group, coordination of activities with Texas, and regional operations research activity. Also included in appendices are: communications to identify Decision Makers, Report to Governor and Legislature on Status of GP/GT Energy in Louisiana, and a paper presented jointly by Louisiana and Texas Project Team at Third Geopressured Geothermal Energy Conference, University of Southwestern Louisiana, Lafayette, Louisiana. (MHR)

  20. Functional microarray analysis suggests repressed cell-cell signaling and cell survival-related modules inhibit progression of head and neck squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Soares Fernando A

    2011-04-01

    Full Text Available Abstract Background Cancer shows a great diversity in its clinical behavior which cannot be easily predicted using the currently available clinical or pathological markers. The identification of pathways associated with lymph node metastasis (N+ and recurrent head and neck squamous cell carcinoma (HNSCC may increase our understanding of the complex biology of this disease. Methods Tumor samples were obtained from untreated HNSCC patients undergoing surgery. Patients were classified according to pathologic lymph node status (positive or negative or tumor recurrence (recurrent or non-recurrent tumor after treatment (surgery with neck dissection followed by radiotherapy. Using microarray gene expression, we screened tumor samples according to modules comprised by genes in the same pathway or functional category. Results The most frequent alterations were the repression of modules in negative lymph node (N0 and in non-recurrent tumors rather than induction of modules in N+ or in recurrent tumors. N0 tumors showed repression of modules that contain cell survival genes and in non-recurrent tumors cell-cell signaling and extracellular region modules were repressed. Conclusions The repression of modules that contain cell survival genes in N0 tumors reinforces the important role that apoptosis plays in the regulation of metastasis. In addition, because tumor samples used here were not microdissected, tumor gene expression data are represented together with the stroma, which may reveal signaling between the microenvironment and tumor cells. For instance, in non-recurrent tumors, extracellular region module was repressed, indicating that the stroma and tumor cells may have fewer interactions, which disable metastasis development. Finally, the genes highlighted in our analysis can be implicated in more than one pathway or characteristic, suggesting that therapeutic approaches to prevent tumor progression should target more than one gene or pathway

  1. Progressive Finland sees progress with nuclear projects

    International Nuclear Information System (INIS)

    The Finnish Hanhikivi-1 reactor project is firmly on track and a licence has been granted for construction of a final disposal facility for spent nuclear fuel - the first final repository in the world to enter the construction phase. Significant progress has been made with plans for Finland to build its sixth nuclear reactor unit at Hanhikivi. Fennovoima's licensing manager Janne Liuko said the company expects to receive the construction licence for the Generation III+ Hanhikivi-1 plant in late 2017. The application was submitted to the Finnish Ministry of Employment and the Economy in June 2015.

  2. Progressive Finland sees progress with nuclear projects

    Energy Technology Data Exchange (ETDEWEB)

    Dalton, David [NucNet, Brussels (Belgium)

    2016-02-15

    The Finnish Hanhikivi-1 reactor project is firmly on track and a licence has been granted for construction of a final disposal facility for spent nuclear fuel - the first final repository in the world to enter the construction phase. Significant progress has been made with plans for Finland to build its sixth nuclear reactor unit at Hanhikivi. Fennovoima's licensing manager Janne Liuko said the company expects to receive the construction licence for the Generation III+ Hanhikivi-1 plant in late 2017. The application was submitted to the Finnish Ministry of Employment and the Economy in June 2015.

  3. Final Harvest of Above-Ground Biomass and Allometric Analysis of the Aspen FACE Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Mark E. Kubiske

    2013-04-15

    The Aspen FACE experiment, located at the US Forest Service Harshaw Research Facility in Oneida County, Wisconsin, exposes the intact canopies of model trembling aspen forests to increased concentrations of atmospheric CO2 and O3. The first full year of treatments was 1998 and final year of elevated CO2 and O3 treatments is scheduled for 2009. This proposal is to conduct an intensive, analytical harvest of the above-ground parts of 24 trees from each of the 12, 30 m diameter treatment plots (total of 288 trees) during June, July & August 2009. This above-ground harvest will be carefully coordinated with the below-ground harvest proposed by D.F. Karnosky et al. (2008 proposal to DOE). We propose to dissect harvested trees according to annual height growth increment and organ (main stem, branch orders, and leaves) for calculation of above-ground biomass production and allometric comparisons among aspen clones, species, and treatments. Additionally, we will collect fine root samples for DNA fingerprinting to quantify biomass production of individual aspen clones. This work will produce a thorough characterization of above-ground tree and stand growth and allocation above ground, and, in conjunction with the below ground harvest, total tree and stand biomass production, allocation, and allometry.

  4. Brittle fracture safety analysis of RPV based on progressive thermo hydraulic analysis; Sproedbruchsicherheitsnachweise von Reaktordruckbehaeltern auf Basis fortschrittlicher thermohydraulischer Analysen

    Energy Technology Data Exchange (ETDEWEB)

    Keim, E.; Hertlein, R. [AREVA NP GmbH (Germany); Ilg, U.; Koenig, G. [AREVA NP GmbH (Germany)]|[EnBW Kernkraft GmbH (Germany); Schlueter, N.; Widera, M. [RWE Power AG (Germany)

    2007-07-01

    The fundamentals of brittle fracture safety analysis of RPV in case of LCA are presented in the following steps: 1. Proof of flawlessness of the RPV and plating after production; 2. Crack postulate: Internal defect with defect depth x safety factor 2 according to non-destructive test and defect type a/2c = 1/6; 3. Exclusion of crack initiation with RT{sub NDT} concept and consideration of maximum load; 4.If necessary, crack arrest as a further barrier. This concept is applied to three types of nuclear power plant: a) KKE, KKPL2, GKN II; b) GKN I; c) Biblis A/B. The thermohydraulic and fracture-mechanical calculaitons and the subsequent safety assessment showed that brittle fracture of RPV in case of LCA can be excluded for all parts of the RPV and for all accident scenarios. (orig.)

  5. SPEAR-BETA fuel-performance code system. COSTF: cost implications analysis postprocessor. Final report

    International Nuclear Information System (INIS)

    The SPEAR-BETA fuel performance code system computes fuel reliability as a function of fuel precharacterization and operating history. This report describes an application of the SPEAR-BETA post-processor, COSTF, to the analysis of fuel failure cost implications for Oyster Creek Cycle 8. COSTF is a model which analyzes the cost implications of fuel failure and failure avoidance operations as a function of fuel precharacterization, operating history and cost parameters. The analysis reports baseline costs, representing those actually incurred during Cycle 8, and effects on these cost items of variations. Included are effects of varying 50 different cost parameters, as well as effects of varying power levels and ramp rates

  6. An economic analysis of a monitored retrievable storage site for Tennessee. Final report and appendices

    Energy Technology Data Exchange (ETDEWEB)

    Fox, W.F.; Mayo, J.W.; Hansen, L.T.; Quindry, K.E.

    1985-12-17

    The United States Department of Energy is charged with the task of identifying potential sites for a Monitored Retrievable Storage (MRS) Facility and reporting the results of its analysis to Congress by January 1986. DOE chose three finalist sites from 11 sites DOE analysts evaluated earlier. All three are in Tennessee, including two in Oak Ridge and one in Trousdale/Smith Counties. This paper is a summary of research undertaken on the economic effects of establishing the MRS facility in Tennessee. All three locations were considered in the analysis, but on some occasions attention is focused on the site preferred by DOE. The research was undertaken by the Center for Business and Economic Research (CBER), College of Business Administration, the University of Tennessee, Knoxville, under contract with the Tennessee Department of Economic and Community Development.

  7. Matrix effects in compositional analysis of bulk materials by PGNAA (prompt gamma/neutron activation analysis). Final report

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, V.C.; Sandquist, G.M.; Merrell, G.B.; Gozani, T.

    1984-08-01

    This feasibility study has identified and evaluated the influence of important matrix effects which arise in the commercial application of prompt gamma/neutron activation analysis (PGNAA) methods to bulk-coal analysis as follows: neutron moderation and absorption changes; gamma-ray attenuation in the sample; sample density and volume changes. The neutron-induced capture gamma spectra were found to vary in a similar, predictable manner for all neutron absorbers found in coal such as hydrogen, boron, nitrogen, chlorine, and sulfur. Three different models have been proposed from this study to analyze coal by PGNAA methods and account for the significant matrix effects arising from hydrogen variation and other system perturbations.

  8. Matrix effects in compositional analysis of bulk materials by PGNAA (prompt gamma/neutron activation analysis). Final report

    International Nuclear Information System (INIS)

    This feasibility study has identified and evaluated the influence of important matrix effects which arise in the commercial application of prompt gamma/neutron activation analysis (PGNAA) methods to bulk-coal analysis as follows: neutron moderation and absorption changes; gamma-ray attenuation in the sample; sample density and volume changes. The neutron-induced capture gamma spectra were found to vary in a similar, predictable manner for all neutron absorbers found in coal such as hydrogen, boron, nitrogen, chlorine, and sulfur. Three different models have been proposed from this study to analyze coal by PGNAA methods and account for the significant matrix effects arising from hydrogen variation and other system perturbations

  9. Social networking and the Olympic Movement: social media analysis, opportunities and trends : final report

    OpenAIRE

    Fernández Peña, Emilio

    2011-01-01

    Table of contents : 1: Introduction. - 2 : Sociodemographic data of social networking sites. - 3 : The Vancouver 2010 Olympic Winter Games on Facebook, Twitter and Orkut. - 4 : Singapore 2010 Youth Olympic Games communication strategies on Facebook and Twitter. - 5 : Sport organizations social networking strategies : case study analysis. - 6 : Olympic athletes and social media use during a non olympic-period. - 7. The Olympic Games, NBA and FC Barcelona on Facebook : content and fan participa...

  10. Final Technical Report: Advanced Measurement and Analysis of PV Derate Factors.

    Energy Technology Data Exchange (ETDEWEB)

    King, Bruce Hardison [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Burton, Patrick D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hansen, Clifford [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Christian Birk [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-12-01

    The Advanced Measurement and Analysis of PV Derate Factors project focuses on improving the accuracy and reducing the uncertainty of PV performance model predictions by addressing a common element of all PV performance models referred to as “derates”. Widespread use of “rules of thumb”, combined with significant uncertainty regarding appropriate values for these factors contribute to uncertainty in projected energy production.

  11. 18th ICPR paper: TOTAL COST OF OWNERSHIP ANALYSIS FOR MODULAR FINAL ASSEMBLY SYSTEMS

    OpenAIRE

    Heilala, Juhani; Helin, Kaj; Montonen, Jari

    2006-01-01

    Abstract The objective of modern assembly processes is to produce high-quality and low-cost products. Understanding manufacturing costs in the system design phase is the first step to increasing profits. Throughput, utilisation and cycle time continue to be emphasised as key performance indicators (KPI) for the planning of new assembly systems, but the cost issues need to be analysed as well. The authors are developing a novel analysis methodology that integrates component-based si...

  12. Final safety analysis report (FSAR) for waste receiving and processing (WRAP) facility

    International Nuclear Information System (INIS)

    This safety analysis report provides a summary description of the WRAP Facility, focusing on significant safety-related characteristics of the location and facility design. This report demonstrates that adherence to the safety basis wi11 ensure necessary operational safety considerations have been addressed sufficiently and justifies the adequacy of the safety basis in protecting the health and safety of the public, workers, and the environment

  13. Geological storage of CO2: risks analysis, monitoring and measures. Final report

    International Nuclear Information System (INIS)

    To use the CO2 geological storage as a coherent solution in the greenhouse gases reduction it needs to answer to safety and monitoring conditions. In this framework the BRGM presents this study in six chapters: risks analysis, the monitoring methods (geochemistry, geophysics, aerial monitoring, biochemistry, hydrogeology), the metrology, the corrosion problems, the thermal, hydrodynamical, geochemical and mechanical simulation and the today and future regulations. (A.L.B.)

  14. Final safety analysis report for the Ground Test Accelerator (GTA), Phase 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    This document is the second volume of a 3 volume safety analysis report on the Ground Test Accelerator (GTA). The GTA program at the Los Alamos National Laboratory (LANL) is the major element of the national Neutral Particle Beam (NPB) program, which is supported by the Strategic Defense Initiative Office (SDIO). A principal goal of the national NPB program is to assess the feasibility of using hydrogen and deuterium neutral particle beams outside the Earth`s atmosphere. The main effort of the NPB program at Los Alamos concentrates on developing the GTA. The GTA is classified as a low-hazard facility, except for the cryogenic-cooling system, which is classified as a moderate-hazard facility. This volume consists of failure modes and effects analysis; accident analysis; operational safety requirements; quality assurance program; ES&H management program; environmental, safety, and health systems critical to safety; summary of waste-management program; environmental monitoring program; facility expansion, decontamination, and decommissioning; summary of emergency response plan; summary plan for employee training; summary plan for operating procedures; glossary; and appendices A and B.

  15. Final Safety Analysis Document for Building 693 Chemical Waste Storage Building at Lawrence Livermore National Laboratory

    International Nuclear Information System (INIS)

    This Safety Analysis Document (SAD) for the Lawrence Livermore National Laboratory (LLNL) Building 693, Chemical Waste Storage Building (desipated as Building 693 Container Storage Unit in the Laboratory's RCRA Part B permit application), provides the necessary information and analyses to conclude that Building 693 can be operated at low risk without unduly endangering the safety of the building operating personnel or adversely affecting the public or the environment. This Building 693 SAD consists of eight sections and supporting appendices. Section 1 presents a summary of the facility designs and operations and Section 2 summarizes the safety analysis method and results. Section 3 describes the site, the facility desip, operations and management structure. Sections 4 and 5 present the safety analysis and operational safety requirements (OSRs). Section 6 reviews Hazardous Waste Management's (HWM) Quality Assurance (QA) program. Section 7 lists the references and background material used in the preparation of this report Section 8 lists acronyms, abbreviations and symbols. Appendices contain supporting analyses, definitions, and descriptions that are referenced in the body of this report

  16. Scoping thermal analysis of the Three Mile Island Unit 2 pressure boundary. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Brown, D.L.; Butzin, D.F.; Calkins, C.A.

    1983-07-01

    A series of exploratory thermal analyses were performed for several regions of the Three Mile Island Unit 2 pressure boundary. The purpose of these analyses was to obtain an estimate of the thermal response of the pressure boundary components to the partial core uncovery accident. The results of this analysis are to be used as input to a subsequent stress analysis and to identify those regions which will require detailed analysis. Four regions were considered for these analyses: (1) the pressure vessel beltline region, (2) the pressure vessel top head region, (3) the outlet nozzle-candy cane pipe region, and (4) the inlet nozzle-inlet piping region. Temperature gradients large enough to warrant evaluation of the stress levels were predicted in three of the four regions under some conditions. The beltline region of the pressure vessel was found to be the least affected by the transient. More detailed evaluation will be required for the inlet piping-nozzle region and the top head in future analyses.

  17. Photovoltaic power systems market identification and analysis. Final report, January 1977--February 1978

    Energy Technology Data Exchange (ETDEWEB)

    1979-05-01

    This report summarizes the work done by InterTechnology/Solar Corporation, its consultants, Mobil Tyco Solar Energy Corporation and the University of Delaware Institute for Energy Conversion, and its consultants, during the marketing analysis of near and intermediate term photovoltaic power applications. To obtain estimates of the domestic and foreign market potential for photovoltaically powered devices two approaches were used. First, the study was identifying then screening all possible photovoltaic power supply applications. This approach encompassed the first two tasks of the study: (1) a survey of the current uses of photovoltaic systems, both domestic and international, and a projection of the usage of those systems into the future; and (2) a new idea generation task which attempted to come up with new ways of using photovoltaic power. Second, the study required in-depth analysis of key near-term and intermediate-term photovoltaic applications identified during the first phase to obtain reasonable estimates of photovoltaic market potential. This process encompassed the third and fourth tasks of the analysis: (3) refinement of ideas generated in Task 2 so that certain products/applications could be identified, the product defined and a market survey carried out; and (4) development of a detailed product scenario which forecasts sales, barriers to market acceptance, and technical innovationsrequired for proper introduction of the products. The work performed and findings of each task are presented.

  18. Analysis of the need for intermediate and peaking technologies in the year 2000. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Barrager, S.M.; Campbell, G.L.

    1980-04-01

    This analysis was conducted to assess the impact of load management on the future need for intermediate- and peak-generating technologies (IPTs) such as combustion turbines, pumped storage, and cycling coal plants. There would be a reduced need for IPTs if load-management activities such as time-of-use pricing, together with customer-owned energy-storage devices, hot-water-heater controls, and interruptible service can economically remove most of the variation from electric power demands. The objective of this analysis is to assess the need for IPTs in an uncertain future, which will probably include load management and time-differentiated electricity prices. The analysis is exploratory in nature and broad in scope. It does not attempt to predict the future or to model precisely the technical characteristics or economic desirability of load management. Rather, its purpose is to provide research and development planners with some basic insights into the order of magnitude of possible hourly demand shifts on a regional basis and to determine the impact of load management on daily and seasonal variations in electricity demand.

  19. THE ECONOMIC ANALYSIS OF LAW - WILL THE ROMANIAN DOCTRINE FINALLY CATCH UP WITH IT?

    Directory of Open Access Journals (Sweden)

    MONICA-FLORENTINA POPA

    2013-05-01

    Full Text Available Although a well-established presence on the international legal scene, the economic analysis of law is still an unfamiliar concept to most Romanian scholars. While worldwide, prestigious universities offer special courses on this topic and an impressive body of legal studies continues to add up, only scant traces of this important legal school can be detected in some recent Romanian doctoral thesis and papers. This article explores the main concepts of the economic analysis of law, the recent spin-offs of this theory, especially in the area of comparative law, as well as some of the critiques addressed in the legal doctrine, concerning the consequences on law of overemphasizing “efficiency” to the expense of less quantifiable, moral and social considerations. Some explanations on why the Romanian doctrine is lagging behind with respect to the economic analysis of law will also be attempted, together with a tentative answer to whether this major legal theory will ever make an impact on local doctrinal developments in the near future.

  20. Ultrascale Visualization Climate Data Analysis Tools (UV-CDAT) Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Dean N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2014-05-19

    A partnership across government, academic, and private sectors has created a novel system that enables climate researchers to solve current and emerging data analysis and visualization challenges. The Ultrascale Visualization Climate Data Analysis Tools (UV-CDAT) software project utilizes the Python application programming interface (API) combined with C/C++/Fortran implementations for performance-critical software that offers the best compromise between "scalability" and “ease-of-use.” The UV-CDAT system is highly extensible and customizable for high-performance interactive and batch visualization and analysis for climate science and other disciplines of geosciences. For complex, climate data-intensive computing, UV-CDAT’s inclusive framework supports Message Passing Interface (MPI) parallelism as well as taskfarming and other forms of parallelism. More specifically, the UV-CDAT framework supports the execution of Python scripts running in parallel using the MPI executable commands and leverages Department of Energy (DOE)-funded general-purpose, scalable parallel visualization tools such as ParaView and VisIt. This is the first system to be successfully designed in this way and with these features. The climate community leverages these tools and others, in support of a parallel client-server paradigm, allowing extreme-scale, server-side computing for maximum possible speed-up.

  1. Stress corrosion cracking in steam turbine disks: analysis of field and laboratory data. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Eason, E.D.

    1985-05-01

    The field data and related laboratory data from many investigators were analyzed to identify the key variables and quantify their effects on stress corrosion cracking of turbine disks. Beginning with over 35 potential variables, pattern recognition and transformation analysis techniques were used to find and characterize the most important variables. The transformation analysis technique was also used to identify laboratory environments that are comparable to the field and to check for lab-to-lab differences in measured crack growth rate. Field data were also analyzed separately, using transformation analysis and order statistics to determine the effects of variables and produce statistical distributions of crack growth rate and failure rate with time. Models were constructed for the field and laboratory data to combine data from many sources and test conditions and to quantify the key variable effects. Two, three, and four variable models were calibrated to the available data. The four variable model is capable of correlating stress corrosion data for 19 low alloy steels with negligible increase in scatter compared to NiCrMoV data. The three variable model describes the behavior of disk steels in the field and comparable laboratory environments. 42 refs., 39 figs., 10 tabs.

  2. Reduced order models for thermal analysis : final report : LDRD Project No. 137807.

    Energy Technology Data Exchange (ETDEWEB)

    Hogan, Roy E., Jr.; Gartling, David K.

    2010-09-01

    This LDRD Senior's Council Project is focused on the development, implementation and evaluation of Reduced Order Models (ROM) for application in the thermal analysis of complex engineering problems. Two basic approaches to developing a ROM for combined thermal conduction and enclosure radiation problems are considered. As a prerequisite to a ROM a fully coupled solution method for conduction/radiation models is required; a parallel implementation is explored for this class of problems. High-fidelity models of large, complex systems are now used routinely to verify design and performance. However, there are applications where the high-fidelity model is too large to be used repetitively in a design mode. One such application is the design of a control system that oversees the functioning of the complex, high-fidelity model. Examples include control systems for manufacturing processes such as brazing and annealing furnaces as well as control systems for the thermal management of optical systems. A reduced order model (ROM) seeks to reduce the number of degrees of freedom needed to represent the overall behavior of the large system without a significant loss in accuracy. The reduction in the number of degrees of freedom of the ROM leads to immediate increases in computational efficiency and allows many design parameters and perturbations to be quickly and effectively evaluated. Reduced order models are routinely used in solid mechanics where techniques such as modal analysis have reached a high state of refinement. Similar techniques have recently been applied in standard thermal conduction problems e.g. though the general use of ROM for heat transfer is not yet widespread. One major difficulty with the development of ROM for general thermal analysis is the need to include the very nonlinear effects of enclosure radiation in many applications. Many ROM methods have considered only linear or mildly nonlinear problems. In the present study a reduced order model is

  3. Toward an Integrated BAC Library Resource for Genome Sequencing and Analysis; FINAL

    International Nuclear Information System (INIS)

    We developed a great deal of expertise in building large BAC libraries from a variety of DNA sources including humans, mice, corn, microorganisms, worms, and Arabidopsis. We greatly improved the technology for screening these libraries rapidly and for selecting appropriate BACs and mapping BACs to develop large overlapping contigs. We became involved in supplying BACs and BAC contigs to a variety of sequencing and mapping projects and we began to collaborate with Drs. Adams and Venter at TIGR and with Dr. Leroy Hood and his group at University of Washington to provide BACs for end sequencing and for mapping and sequencing of large fragments of chromosome 16. Together with Dr. Ian Dunham and his co-workers at the Sanger Center we completed the mapping and they completed the sequencing of the first human chromosome, chromosome 22. This was published in Nature in 1999 and our BAC contigs made a major contribution to this sequencing effort. Drs. Shizuya and Ding invented an automated highly accurate BAC mapping technique. We also developed long-term collaborations with Dr. Uli Weier at UCSF in the design of BAC probes for characterization of human tumors and specific chromosome deletions and breakpoints. Finally the contribution of our work to the human genome project has been recognized in the publication both by the international consortium and the NIH of a draft sequence of the human genome in Nature last year. Dr. Shizuya was acknowledged in the authorship of that landmark paper. Dr. Simon was also an author on the Venter/Adams Celera project sequencing the human genome that was published in Science last year

  4. Final Report for Dynamic Models for Causal Analysis of Panel Data. Dynamic Analysis of Event Histories. Part III, Chapter 1.

    Science.gov (United States)

    Tuma, Nancy Brandon; Hannan, Michael T.

    The document, part of a series of chapters described in SO 011 759, examines sociological research methods for the study of change. The advantages and procedures for dynamic analysis of event-history data (data giving the number, timing, and sequence of changes in a categorical dependent variable) are considered. The authors argue for grounding…

  5. Using the Advanced Progressive Matrices (Set I) to Assess Fluid Ability in a Short Time Frame: An Item Response Theory-Based Analysis

    Science.gov (United States)

    Chiesi, Francesca; Ciancaleoni, Matteo; Galli, Silvia; Primi, Caterina

    2012-01-01

    This article is aimed at evaluating the possibility that Set I of the Advanced Progressive Matrices (APM-Set I) can be employed to assess fluid ability in a short time frame. The APM-Set I was administered to a sample of 1,389 primary and secondary school students. Confirmatory factor analysis attested to the unidimensionality of the scale. Item…

  6. Innovative conservation housing. Final progress report

    Energy Technology Data Exchange (ETDEWEB)

    Nuttle, D.A.

    1983-01-01

    A new passive solar thermal storage brick was developed and tested. A new insulating curtain concept was developed to assist in passive solar heating and cooling. A steel truss was designed to replace the wood truss in solar attic applications where the wood truss typically suffers some 50% loss of structural strength. Improvements were made of the dry composting toilet and grey water recycling for homes. An algae cultivation system was created for production of food, feed, fertilizer, or biomass as needed for home, farm, or industry. New concepts were explored in the areas of economy shelter, solar hot water heating, home generation of electricity, edible landscapes and other home food production, growing of fiber crops for cottage industry, storage, insulation, solar cooking, and solar refrigeration. (LEW)

  7. Chemical Reactions at Surfaces. Final Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2003-02-21

    The Gordon Research Conference (GRC) on Chemical Reactions at Surfaces was held at Holiday Inn, Ventura, California, 2/16-21/03. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

  8. ESG-CET Final Progress Title

    Energy Technology Data Exchange (ETDEWEB)

    Don Middleton

    2011-10-06

    Drawing to a close after five years of funding from DOE's ASCR and BER program offices, the SciDAC-2 project called the Earth System Grid (ESG) Center for Enabling Technologies has successfully established a new capability for serving data from distributed centers. The system enables users to access, analyze, and visualize data using a globally federated collection of networks, computers and software. The ESG software - now known as the Earth System Grid Federation (ESGF) - has attracted a broad developer base and has been widely adopted so that it is now being utilized in serving the most comprehensive multi-model climate data sets in the world. The system is used to support international climate model intercomparison activities as well as high profile U.S. DOE, NOAA, NASA, and NSF projects. It currently provides more than 25,000 users access to more than half a petabyte of climate data (from models and from observations) and has enabled over a 1,000 scientific publications.

  9. Primera Reunion de la Comision Nacional de Analisis y Evaluacion del Sistema Educativo: Informe Final (The First Meeting of the National Committee for Analysis and Evaluation of the Educational System: Final Report).

    Science.gov (United States)

    Ministerio de Cultura y Educacion, Buenos Aires (Argentina). Centro National de Documentacion e Informacion Educativa.

    This document contains the legislation creating the National Committee for Analysis and Evaluation of the Educational System and the final report of that committee's first meeting. The report deals with each level from elementary to higher education. For each level it describes and considers curriculum, school buildings, human resources, current…

  10. Final report. Geothermal Energy Program: Information dissemination, public outreach, and technical analysis activities. April 1, 1999 to December 31, 2001. USDOE Grant No. DE-FG01-99-EE35098; FINAL

    International Nuclear Information System (INIS)

    This is the final report of the accomplishments of the geothermal energy program: information dissemination, public outreach, and technical analysis activities by the project team consisting of the Geo-Heat Center, Geothermal Resources Council, Geothermal Education Office, Geothermal Energy Association, and the Washington State University Energy Program

  11. Final disposal of spent fuel in the Finnish bedrock. Scope and requirements for site-specific safety analysis

    International Nuclear Information System (INIS)

    The report is a summary of the research conducted in the period 1993 to 1996 into safety of spent fuel final disposal. The principal goal of the research in this period, as set in 1993, was to develop a strategy for site-specific safety analysis. At the same time efforts were to be continued to gather data and validate the technical approach for the analysis. The work aimed at having the data needed for the analysis available at the end of year 1998. A safety assessment update, TILA-96, prepared by VTT Energy, is published as a separate report. The assessment is based on the TVO-92 safety analysis, but takes into account the knowledge acquired after 1992 on safety aspects of the disposal system and the data gathered from the site investigations made by TVO and from the beginning of 1996, by Posiva. Since the site investigations are still ongoing and much of the data gathered still pending interpretation, only limited amount of new site-specific information has been available for the present assessment. (172 refs.)

  12. Operations research and systems analysis of geothermal/geopressured resources in Texas. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Zinn, C.D.

    1977-12-01

    Existing data pertinent to preliminary geopressured development scenarios were reviewed. Assumptions for constructing development scenarios based upon high, nominal, and low energy development rates are formulated and reviewed. Initial geothermal/geopressured development scenarios were formulated. The initial development scenarios were reviewed with representatives of local and state governments, industry, and community groups. A detailed analysis of the preliminary scenarios is given. Organizations in the state of Texas that have an interest in and/or responsibility for geothermal/geopressured resources were identified. Work toward the creation of a regional planning support organization is reviewed. (MHR)

  13. Analysis of Chinook Salmon in the Columbia River from an Ecosystem Perspective. Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Lichatowich, James A.; Mobrand, Lars E.

    1995-01-01

    Ecosystem Diagnosis and Treatment (EDT) methodology was applied to the analysis of chinook salmon in the mid-Columbia subbasins which flow through the steppe and steppe-shrub vegetation zones. The EDT examines historical changes in life history diversity related to changes in habitat. The emphasis on life history, habitat and historical context is consistent with and ecosystem perspective. This study is based on the working hypothesis that the decline in chinook salmon was at least in part due to a loss of biodiversity defined as the intrapopulation life history diversity. The mid Columbia subbasins included in the study are the Deschutes, John Day, Umatilla, Tucannon and Yakima.

  14. Conceptual design and systems analysis of photovoltaic power systems. Volume II. Systems. Revised final report

    Energy Technology Data Exchange (ETDEWEB)

    Pittman, P.F.

    1977-03-01

    Conceptual designs were made and analyses were performed on three types of solar photovoltaic power systems. Included were Residential (1--10 kW), Intermediate (0.1--10 MW), and Central (50--1000 MW) Power Systems to be installed in the 1985 to 2000 time period. Detailed descriptions of each of the three systems studied, descriptions of the necessary subsystems, and discussions of the interfaces between them are presented. Included also are descriptions of system performance and system cost used to perform an economic analysis which assesses the value of each system.

  15. Conceptual design and systems analysis of photovoltaic power systems. Final report. Volume III(2). Technology

    Energy Technology Data Exchange (ETDEWEB)

    Pittman, P.F.

    1977-05-01

    Conceptual designs were made and analyses were performed on three types of solar photovoltaic power systems. Included were Residential (1 to 10 kW), Intermediate (0.1 to 10 MW), and Central (50 to 1000 MW) Power Systems to be installed in the 1985 to 2000 time period. The following analyses and simulations are covered: residential power system computer simulations, intermediate power systems computer simulation, central power systems computer simulation, array comparative performance, utility economic and margin analyses, and financial analysis methodology.

  16. Improvement and verification of fast-reactor safety-analysis techniques. Final report

    International Nuclear Information System (INIS)

    The work involved on this project took place between March 1, 1975 and December 31, 1981. The work resulted in two PhD and one Masters Theses. Part I was the Verification and Applicability Studies for the VENUS-II LMFBR Disassembly Code. These tests showed that the VENUS-II code closely predicted the energy release in all three tests chosen for analysis. Part II involved the chemical simulation of pool dispersion in the transition phase of an HCDA. Part III involved the reaction of an internally heated fluid and the vessel walls

  17. Predictive factors of radiological progression after 2 years of remission-steered treatment in early arthritis patients: a post hoc analysis of the IMPROVED study

    Science.gov (United States)

    Akdemir, Gülşah; Verheul, Marije K; Heimans, Lotte; Wevers-de Boer, Kirsten V C; Goekoop-Ruiterman, Yvonne P M; van Oosterhout, Maikel; Harbers, Joop B; Bijkerk, Casper; Steup-Beekman, Gerda M; Lard, Leroy R; Huizinga, Tom W J; Trouw, Leendert A; Allaart, Cornelia F

    2016-01-01

    Objectives To identify predictive factors of radiological progression in early arthritis patients treated by remission-steered treatment. Methods In the IMPROVED study, 610 patients with early rheumatoid arthritis (RA) or undifferentiated arthritis (UA) were treated with methotrexate (MTX) and a tapered high dose of prednisone. Patients in early remission (disease activity score (DAS) <1.6 after 4 months) tapered prednisone to zero. Patients not in early remission were randomised to arm 1: MTX plus hydroxychloroquine, sulfasalazine and prednisone, or to arm 2: MTX plus adalimumab. Predictors of radiological progression (≥0.5 Sharp/van der Heijde score; SHS) after 2 years were assessed using logistic regression analysis. Results Median (IQR) SHS progression in 488 patients was 0 (0–0) point, without differences between RA or UA patients or between treatment arms. In only 50/488 patients, the SHS progression was ≥0.5: 33 (66%) were in the early DAS remission group, 9 (18%) in arm 1, 5 (10%) in arm 2, 3 (6%) in the outside of protocol group. Age (OR (95% CI): 1.03 (1.00 to 1.06)) and the combined presence of anticarbamylated protein antibodies (anti-CarP) and anticitrullinated protein antibodies (ACPA) (2.54 (1.16 to 5.58)) were independent predictors for SHS progression. Symptom duration <12 weeks showed a trend. Conclusions After 2 years of remission steered treatment in early arthritis patients, there was limited SHS progression in only a small group of patients. Numerically, patients who had achieved early DAS remission had more SHS progression than other patients. Positivity for both anti-CarP and ACPA and age were independently associated with SHS progression. Trial registration numbers ISRCTN Register number 11916566 and EudraCT number 2006 06186-16. PMID:26925251

  18. Improvement and evaluation of methods for sulfate analysis. Part II. Final report Oct 78-May 79

    International Nuclear Information System (INIS)

    Methods for extraction of sulfate from glass-fiber hi-vol and Teflon lo-vol samples were evaluated. Efficiencies were found to vary with sampling location up to 20%. Mechanical shaking in water at room temperature was significantly more efficient than ultrasonic or reflux techniques with hi-vol samples. While Teflon filters are not wet by water, pre-wetting of filters with methanol did not significantly enhance sulfate extraction. A turbidimetric sulfate method using SulfaVer IV was evaluated for ruggedness, precision and intermethod agreement. Its precision was at least equal to that of a conventional turbidimetric method, but its accuracy was somewhat less, especially at lower sulfate levels. The Dionex Model 10 ion chromatograph was evaluated for low level sulfate analysis using both a sample preconcentrator and large (0.5 ml) sample loop. The latter was the preferred technique for samples = or < 20 microgram/ml. Accuracy was within 15% in the range 2 to 20 microgram/ml with a median C.V. of 6.5% for 24 atmospheric samples collected with dichotomous samplers. Use of a sample pre-concentrator permitted analysis of samples containing < 1 microgram/ml sulfate

  19. Analysis of the premitting processes associated with exploration of Federal OCS leases. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1980-11-01

    Under contract to the Office of Leasing Policy Development (LPDO), Jack Faucett Associates is currently undertaking the description and analysis of the Outer Continental Shelf (OCS) regulatory process to determine the nature of time delays that affect OCS production of oil and gas. This report represents the results of the first phase of research under this contract, the description and analysis of regulatory activity associated with exploration activities on the Federal OCS. Volume 1 contains the following three sections: (1) study results; (2) Federal regulatory activities during exploration of Federal OCS leases which involved the US Geological Survey, Environmental Protection Agency, US Coast Guard, Corps of Engineers, and National Ocean and Atmospheric Administration; and (3) state regulatory activities during exploration of Federal OCS leases of Alaska, California, Louisiana, Massachusetts, New Jersey, North Carolina, and Texas. Volume II contains appendices of US Geological Survey, Environmental Protection Agency, Coast Guard, Corps of Engineers, the Coastal Zone Management Act, and Alaska. The major causes of delay in the regulatory process governing exploration was summarized in four broad categories: (1) the long and tedious process associated with the Environmental Protection Agency's implementation of the National Pollutant Discharge Elimination System Permit; (2) the lack of mandated time periods for the completion of individual activities in the permitting process; (3) the lack of overall coordination of OCS exploratory regulation; and (4) the inexperience of states, the Federal government and industry relating to the appropriate level of regulation for first-time lease sale areas.

  20. Analysis of the 5-year final dataset of the Supernova Legacy Survey project

    International Nuclear Information System (INIS)

    The Supernova Legacy Survey (SNLS) is a program that aims at discovering and photometrically following hundreds of Type Ia supernovae (SNe Ia). Its goal is to measure the expansion history of the Universe in order to constrain the nature of the dark energy, namely its equation of state wDE. The survey completed its data taking during summer 2008 after 5 years of program. This thesis work consists in the analysis of these 5 years of SNLS data and the photometry of the 419 Type Ia supernovae discovered and spectroscopically identified. For each supernova, the light-curves are produced in the gMrMiMzM bands, calibrated and fitted with a spectrophotometric model. A new photometric method which does not make use of any pixel re-sampling has also been implemented and tested. This method preserves the pixels statistical properties, and produces this way more accurate flux measurement statistical uncertainties, that can be propagated to cosmological measurements. Both photometry results were checked and compared using calibration stars and supernovae, proving that the accuracy of the new method flux measurement uncertainty is indeed better, and that the photometric accuracy and stability of both techniques are similar. A sample of supernovae with unprecedented statistics and quality is now available for cosmological analysis. With the complement of an external nearby supernovae sample, a measurement within 5% of the dark energy equation of state of dark energy is thus for the first time within reach. (author)