WorldWideScience

Sample records for analysis center opar

  1. OpaR controls a network of downstream transcription factors in Vibrio parahaemolyticus BB22OP.

    Directory of Open Access Journals (Sweden)

    Alison Kernell Burke

    Full Text Available Vibrio parahaemolyticus is an emerging world-wide human pathogen that is associated with food-borne gastroenteritis when raw or undercooked seafood is consumed. Expression of virulence factors in this organism is modulated by the phenomenon known as quorum sensing, which permits differential gene regulation at low versus high cell density. The master regulator of quorum sensing in V. parahaemolyticus is OpaR. OpaR not only controls virulence factor gene expression, but also the colony and cellular morphology associated with growth on a surface and biofilm formation. Whole transcriptome Next Generation sequencing (RNA-Seq was utilized to determine the OpaR regulon by comparing strains BB22OP (opaR+, LM5312 and BB22TR (∆opaR1, LM5674. This work, using the published V. parahaemolyticus BB22OP genome sequence, confirms and expands upon a previous microarray analysis for these two strains that used an Affymetrix GeneChip designed from the closely related V. parahaemolyticus RIMD2210633 genome sequence. Overall there was excellent correlation between the microarray and RNA-Seq data. Eleven transcription factors under OpaR control were identified by both methods and further confirmed by quantitative reverse transcription PCR (qRT-PCR analysis. Nine of these transcription factors were demonstrated to be direct OpaR targets via in vitro electrophoretic mobility shift assays with purified hexahistidine-tagged OpaR. Identification of the direct and indirect targets of OpaR, including small RNAs, will enable the construction of a network map of regulatory interactions important for the switch between the nonpathogenic and pathogenic states.

  2. Expression of the Type VI Secretion System 1 Component Hcp1 Is Indirectly Repressed by OpaR in Vibrio parahaemolyticus

    Directory of Open Access Journals (Sweden)

    Lizhi Ma

    2012-01-01

    Full Text Available The type VI secretion system (T6SS is bacterial protein injection machinery with roles in virulence, symbiosis, interbacterial interaction, antipathogenesis, and environmental stress responses. There are two T6SS loci, T6SS1 and T6SS2, in the two chromosomes of Vibrio parahaemolyticus, respectively. This work disclosed that the master quorum sensing (QS regulator OpaR repressed the transcription of hcp1 encoding the structural component Hcp1 of T6SS1 in V. parahaemolyticus, indicating that QS had a negative regulatory action on T6SS1. A single σ54-dependent promoter was transcribed for hcp1 in V. parahaemolyticus, and its activity was repressed by the OpaR regulator. Since the OpaR protein could not bind to the upstream region of hcp1, OpaR would repress the transcription of hcp1 in an indirect manner.

  3. Chemical Security Analysis Center

    Data.gov (United States)

    Federal Laboratory Consortium — In 2006, by Presidential Directive, DHS established the Chemical Security Analysis Center (CSAC) to identify and assess chemical threats and vulnerabilities in the...

  4. NMA Analysis Center

    Science.gov (United States)

    Kierulf, Halfdan Pascal; Andersen, Per Helge

    2013-01-01

    The Norwegian Mapping Authority (NMA) has during the last few years had a close cooperation with Norwegian Defence Research Establishment (FFI) in the analysis of space geodetic data using the GEOSAT software. In 2012 NMA has taken over the full responsibility for the GEOSAT software. This implies that FFI stopped being an IVS Associate Analysis Center in 2012. NMA has been an IVS Associate Analysis Center since 28 October 2010. NMA's contributions to the IVS as an Analysis Centers focus primarily on routine production of session-by-session unconstrained and consistent normal equations by GEOSAT as input to the IVS combined solution. After the recent improvements, we expect that VLBI results produced with GEOSAT will be consistent with results from the other VLBI Analysis Centers to a satisfactory level.

  5. Data Analysis and Assessment Center

    Data.gov (United States)

    Federal Laboratory Consortium — The DoD Supercomputing Resource Center (DSRC) Data Analysis and Assessment Center (DAAC) provides classified facilities to enhance customer interactions with the ARL...

  6. Italy INAF Analysis Center Report

    Science.gov (United States)

    Negusini, M.; Sarti, P.

    2013-01-01

    This report summarizes the activity of the Italian INAF VLBI Analysis Center. Our Analysis Center is located in Bologna, Italy and belongs to the Institute of Radioastronomy, which is part of the National Institute of Astrophysics. IRA runs the observatories of Medicina and Noto, where two 32-m VLBI AZ-EL telescopes are situated. This report contains the AC's VLBI data analysis activities and shortly outlines the investigations into the co-locations of space geodetic instruments.

  7. Kennedy Space Center Spaceport Analysis

    Science.gov (United States)

    Wary, Samantha A.

    2013-01-01

    Until the Shuttle Atlantis' final landing on July 21, 2011, Kennedy Space Center (KSC) served as NASA's main spaceport, which is a launch and landing facility for rockets and spacecraft that are attempting to enter orbit. Many of the facilities at KSC were created to assist the Shuttle Program. One of the most important and used facilities is the Shuttle Landing Facility (SLF), This was the main landing area for the return of the shuttle after her mission in space. · However, the SLF has also been used for a number of other projects including straight-line testing by Gibbs Racing, weather data collection by NOAA, and an airfield for the KSC helicopters. This runway is three miles long with control tower at midfield and a fire department located at the end in care of an emergency. This facility, which was part of the great space race, will continue to be used for historical events as Kennedy begins to commercialize its facilities. KSC continues to be an important spaceport to the government, and it will transform into an important spaceport for the commercial industry as well. During my internship at KSC's Center Planning and Development Directorate, I had the opportunity to be a part of the negotiation team working on the agreement for Space Florida to control the Shuttle Landing Facility. This gave me the opportunity to learn about all the changes that are occurring here at Kennedy Space Center. Through various meetings, I discovered the Master Plan and its focus is to transform the existing facilities that were primarily used for the Shuttle Program, to support government operations and commercial flights in the future. This. idea is also in a new strategic business plan and completion of a space industry market analysis. All of these different documentations were brought to my attention and I. saw how they came together in the discussions of transitioning the SLF to a commercial operator, Space Florida. After attending meetings and partaking in discussions for

  8. Transportation Research & Analysis Computing Center

    Data.gov (United States)

    Federal Laboratory Consortium — The technical objectives of the TRACC project included the establishment of a high performance computing center for use by USDOT research teams, including those from...

  9. Transportation Research & Analysis Computing Center

    Data.gov (United States)

    Federal Laboratory Consortium — The technical objectives of the TRACC project included the establishment of a high performance computing center for use by USDOT research teams, including those from...

  10. Clean Energy Manufacturing Analysis Center (CEMAC)

    Energy Technology Data Exchange (ETDEWEB)

    2015-12-01

    The U.S. Department of Energy's Clean Energy Manufacturing Analysis Center (CEMAC) provides objective analysis and up-to-date data on global supply chains and manufacturing of clean energy technologies. Policymakers and industry leaders seek CEMAC insights to inform choices to promote economic growth and the transition to a clean energy economy.

  11. SHAO Analysis Center 2012 Annual Report

    Science.gov (United States)

    Wang, Guangli; Li, Jinling; Xu, Minghui; Guo, Li; Liu, Li; Shu, Fengchun; Qian, Zhihan; Li, Liang

    2013-01-01

    The Shanghai Astronomical Observatory (SHAO) Analysis Center in 2012 continued routine VLBI data analysis and produced earth orientation parameter (EOP), terrestrial reference frame (TRF), and celestial reference frame (CRF) information, which was submitted to the IVS quarterly. The activities of SHAO also consisted of data reduction of the Chinese VLBI Network (CVN), spacecraft navigation using the VLBI technique, and some research activities.

  12. Rehabilitation centers: marketing analysis and future challenges.

    Science.gov (United States)

    Chandra, Ashish; Stroube, William B; Willis, William K

    2014-01-01

    A rehabilitation center is another form of health care organization that specializes in providing care for particular conditions of patients. Patients admitted in rehab centers range from being accident victims to those suffering with a specific illness. These organizations are becoming extremely valuable in providing patient care services. However, they have not marketed themselves as aggressively as other health care organizations. This article provides an insight regarding rehab centers and examines marketing issues using a SWOT (strengths, weaknesses, opportunities, and threats) analysis. It further provides some future prospects and challenges for marketers of these organizations.

  13. D0 regional analysis center concepts

    Energy Technology Data Exchange (ETDEWEB)

    Lee Lueking et al.

    2003-08-12

    The D0 experiment is facing many exciting challenges providing a computing environment for its worldwide collaboration. Transparent access to data for processing and analysis has been enabled through deployment of its SAM system to collaborating sites and additional functionality will be provided soon with SAMGrid components. In order to maximize access to global storage, computational and intellectual resources, and to enable the system to scale to the large demands soon to be realized, several strategic sites have been identified as Regional Analysis Centers (RAC's). These sites play an expanded role within the system. The philosophy and function of these centers is discussed and details of their composition and operation are outlined. The plan for future additional centers is also addressed.

  14. National Infrastructure Simulation and Analysis Center Overview

    Energy Technology Data Exchange (ETDEWEB)

    Berscheid, Alan P. [Los Alamos National Laboratory

    2012-07-30

    National Infrastructure Simulation and Analysis Center (NISAC) mission is to: (1) Improve the understanding, preparation, and mitigation of the consequences of infrastructure disruption; (2) Provide a common, comprehensive view of U.S. infrastructure and its response to disruptions - Scale & resolution appropriate to the issues and All threats; and (3) Built an operations-tested DHS capability to respond quickly to urgent infrastructure protection issues.

  15. The Joint Physics Analysis Center: Recent results

    CERN Document Server

    Fernandez-Ramirez, Cesar

    2016-01-01

    We review some of the recent achievements of the Joint Physics Analysis Center, a theoretical collaboration with ties to experimental collaborations, that aims to provide amplitudes suitable for the analysis of the current and forthcoming experimental data on hadron physics. Since its foundation in 2013, the group is focused on hadron spectroscopy in preparation for the forthcoming high statistics and high precision experimental data from BELLEII, BESIII, CLAS12, COMPASS, GlueX, LHCb and (hopefully) PANDA collaborations. So far, we have developed amplitudes for $\\pi N$ scattering, $\\bar{K}N$ scattering, pion and $J/\\psi$ photoproduction, two kaon photoproduction and three-body decays of light mesons ($\\eta$, $\\omega$, $\\phi$). The codes for the amplitudes are available to download from the group web page and can be straightforwardly incorporated to the analysis of the experimental data.

  16. The Joint Physics Analysis Center: Recent results

    Science.gov (United States)

    Fernández-Ramírez, César

    2016-10-01

    We review some of the recent achievements of the Joint Physics Analysis Center, a theoretical collaboration with ties to experimental collaborations, that aims to provide amplitudes suitable for the analysis of the current and forthcoming experimental data on hadron physics. Since its foundation in 2013, the group is focused on hadron spectroscopy in preparation for the forthcoming high statistics and high precision experimental data from BELLEII, BESIII, CLAS12, COMPASS, GlueX, LHCb and (hopefully) PANDA collaborations. So far, we have developed amplitudes for πN scattering, KN scattering, pion and J/ψ photoproduction, two kaon photoproduction and three-body decays of light mesons (η, ω, ϕ). The codes for the amplitudes are available to download from the group web page and can be straightforwardly incorporated to the analysis of the experimental data.

  17. An Analysis of Navy Managed Child Development Centers

    Science.gov (United States)

    2015-06-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT AN ANALYSIS OF NAVY MANAGED CHILD DEVELOPMENT CENTERS......return on investment for the Navy and its members. 14. SUBJECT TERMS: Child Care, CDC, Child Development Center, subsidy, cost analysis

  18. Systems Analysis of a Learning Resources Center.

    Science.gov (United States)

    Carman, Robert A.

    This paper examines the needs of the failure-oriented junior college student, presents the learning resources center as a major tool in junior college instruction, and develops a systems approach to the design of a comprehensive learning resources center. Since junior colleges accept a full range of students, including many of low ability,…

  19. Understanding wellness center loyalty through lifestyle analysis.

    Science.gov (United States)

    Suresh, Satya; Ravichandran, Swathi; P, Ganesan

    2011-01-01

    Many changes taking place at a macro-level in Indian society along with the popularity of services that are native to India, such as Yoga and Ayurveda, have generated significant interest in wellness services. To assist wellness centers in gaining loyal clients, the goal of this study was to understand the influence of customer lifestyle factors on wellness center loyalty. The activities, interests, and opinions model was used to understand the lifestyles of wellness center clients. Data were collected from clients of five wellness centers. Regression results indicate that overworked individuals and those seeking a balance between work and family life would be the most loyal to wellness centers. Managerial implications of results are discussed.

  20. Analysis of the Entanglement with Centers

    CERN Document Server

    Huang, Xing

    2016-01-01

    Entanglement in gauge theories is difficult to define because of the issue of a tensor product decomposition of a Hilbert space. We choose centers to define quantities that quantify the entanglement, and also use quantization algebras and constraints to analyze the existence of the ambiguities in a system of first-order formulation. In interacting theories, lattice simulations is required to obtain quantitative behaviors of entanglement. Thus, we propose a method to study entanglement with centers on finite spacing lattice without breaking gauge symmetry. We also understand the relation between the extended lattice model and boundary condition, and discuss magnetic choices in the extended lattice model. Then we compute the entanglement entropy in $p$-form free theory in $2p+2$ dimensional Euclidean flat background with a $S^{2p}$ entangling surface, our results support that the ambiguities in non-gauge theories only affect the regulator dependent terms. The universal terms of the entanglement entropy in $p$-f...

  1. Alternatives to Center of Gravity Analysis

    Science.gov (United States)

    2013-04-04

    20 Figure 11. SWOT Analysis ...SMTs for external and internal environment analysis to identify a basis for a company to recognize areas of opportunity, strategic options, and...Opportunities, and Threats ( SWOT ) analysis . SWOT identifies external and internal factors that impinge on the business (Figure 11). SWOT can be as

  2. Psychrometric Bin Analysis for Alternative Cooling Strategies in Data Centers

    Energy Technology Data Exchange (ETDEWEB)

    Metzger, I.; VanGeet, O.; Rockenbaugh, C.; Dean, J.; Kurnik, C.

    2011-01-01

    Data centers are significant energy users and require continuous cooling to maintain high levels of computing performance. The majority of data centers have direct-expansion cooling which typically accounts for approximately 50% of the energy usage of data centers. However, using typical meteorological year 3 (TMY3) weather data and a simple psychometric bin analysis, alternative cooling strategies using a combination of economizer, evaporative, and supplemental DX cooling have been shown to be applicable in all climate zones in the United States. Average data center cooling energy savings across the U.S. was approximately 80%. Analysis of cooling energy savings is presented for various ASHRAE climate zones. The psychometric bin analysis is conducted for the ASHRAE recommended and allowable operating environment zones, as well as, a modified allowable operating environment. Control strategies are discussed. Finally, examples of energy efficient data centers using alternative cooling strategies are presented.

  3. NUCLEAR FORENSICS ANALYSIS CENTER FORENSIC ANALYSIS TO DATA INTERPRETATION

    Energy Technology Data Exchange (ETDEWEB)

    Nichols, T.

    2011-02-07

    The Nuclear Forensics Analysis Center (NFAC) is part of Savannah River National Laboratory (SRNL) and is one of only two USG National Laboratories accredited to perform nuclear forensic analyses to the requirements of ISO 17025. SRNL NFAC is capable of analyzing nuclear and radiological samples from bulk material to ultra-trace samples. NFAC provides analytical support to the FBI's Radiological Evidence Examination Facility (REEF), which is located within SRNL. REEF gives the FBI the capability to perform traditional forensics on material that is radiological and/or is contaminated. SRNL is engaged in research and development efforts to improve the USG technical nuclear forensics capabilities. Research includes improving predictive signatures and developing a database containing comparative samples.

  4. Hydrogeomorphic (HGM) Analysis : Natural Resource Program Center

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This factsheet describes hydrogeomorphic (HGM) analysis, a three-step process used to evaluate riparian and wetland ecosystems and surrounding landscapes.

  5. Benefits Analysis of Multi-Center Dynamic Weather Routes

    Science.gov (United States)

    Sheth, Kapil; McNally, David; Morando, Alexander; Clymer, Alexis; Lock, Jennifer; Petersen, Julien

    2014-01-01

    Dynamic weather routes are flight plan corrections that can provide airborne flights more than user-specified minutes of flying-time savings, compared to their current flight plan. These routes are computed from the aircraft's current location to a flight plan fix downstream (within a predefined limit region), while avoiding forecasted convective weather regions. The Dynamic Weather Routes automation has been continuously running with live air traffic data for a field evaluation at the American Airlines Integrated Operations Center in Fort Worth, TX since July 31, 2012, where flights within the Fort Worth Air Route Traffic Control Center are evaluated for time savings. This paper extends the methodology to all Centers in United States and presents benefits analysis of Dynamic Weather Routes automation, if it was implemented in multiple airspace Centers individually and concurrently. The current computation of dynamic weather routes requires a limit rectangle so that a downstream capture fix can be selected, preventing very large route changes spanning several Centers. In this paper, first, a method of computing a limit polygon (as opposed to a rectangle used for Fort Worth Center) is described for each of the 20 Centers in the National Airspace System. The Future ATM Concepts Evaluation Tool, a nationwide simulation and analysis tool, is used for this purpose. After a comparison of results with the Center-based Dynamic Weather Routes automation in Fort Worth Center, results are presented for 11 Centers in the contiguous United States. These Centers are generally most impacted by convective weather. A breakdown of individual Center and airline savings is presented and the results indicate an overall average savings of about 10 minutes of flying time are obtained per flight.

  6. A patient-centered care ethics analysis model for rehabilitation.

    Science.gov (United States)

    Hunt, Matthew R; Ells, Carolyn

    2013-09-01

    There exists a paucity of ethics resources tailored to rehabilitation. To help fill this ethics resource gap, the authors developed an ethics analysis model specifically for use in rehabilitation care. The Patient-Centered Care Ethics Analysis Model for Rehabilitation is a process model to guide careful moral reasoning for particularly complex or challenging matters in rehabilitation. The Patient-Centered Care Ethics Analysis Model for Rehabilitation was developed over several iterations, with feedback at different stages from rehabilitation professionals and bioethics experts. Development of the model was explicitly informed by the theoretical grounding of patient-centered care and the context of rehabilitation, including the International Classification of Functioning, Disability and Health. Being patient centered, the model encourages (1) shared control of consultations, decisions about interventions, and management of the health problems with the patient and (2) understanding the patient as a whole person who has individual preferences situated within social contexts. Although the major process headings of the Patient-Centered Care Ethics Analysis Model for Rehabilitation resemble typical ethical decision-making and problem-solving models, the probes under those headings direct attention to considerations relevant to rehabilitation care. The Patient-Centered Care Ethics Analysis Model for Rehabilitation is a suitable tool for rehabilitation professionals to use (in real time, for retrospective review, and for training purposes) to help arrive at ethical outcomes.

  7. Verified centers, nonverified centers, or other facilities: a national analysis of burn patient treatment location.

    Science.gov (United States)

    Zonies, David; Mack, Christopher; Kramer, Bradley; Rivara, Frederick; Klein, Matthew

    2010-03-01

    Although comprehensive burn care requires significant resources, patients may be treated at verified burn centers, nonverified burn centers, or other facilities due to a variety of factors. The purpose of this study was to evaluate the association between patient and injury characteristics and treatment location using a national database. We performed an analysis of all burn patients admitted to United States hospitals participating in the Healthcare Cost and Utilization Project over 2 years. Univariate and multivariate analyses were performed to identify patient and injury factors associated with the likelihood of treatment at designated burn care facilities. Definitive care facilities were categorized as American Burn Association-verified centers, nonverified burn centers, or other facilities. During the 2 years of the study, 29,971 burn patients were treated in 1,376 hospitals located in 19 participating states. A total of 6,712 (22%) patients were treated at verified centers, with 26% and 52% treated at nonverified or other facilities, respectively. Patients treated at verified centers were younger than those treated at nonverified or other facilities (33.1 years versus 33.7 years versus 41.9 years; p facilities. Published by Elsevier Inc.

  8. The National Center for Ecological Analysis and Synthesis

    Science.gov (United States)

    Reichman, O. J.

    2001-12-01

    The National Center for Ecological Analysis and Synthesis was created in May 1995 with funding from NSF, the State of California, and UCSB. The Center is based on the premise that a significant amount is known about the environment, but that it is scattered in many places and formats. The purpose of the Center is to obtain and utilize existing information to address important ecological questions. The Center was recently funded by NSF for an additional 6 years. The Center supports several types of research activities. A primary mode of research is through Working Groups, projects made up of approximately a dozen scientists who come to NCEAS to concentrate on specific issues that require in-depth analysis of data and synthesis of ideas. In addition, up to six sabbatical visitors (Center Fellows) and 18 Postdoctoral Associates are in residence at the Center. Since the Center began, over 2,400 scientists (including hundreds of students) from the US and 40 other countries have participated in research activities. These scientists have produced more than 380 scientific articles published in 65 journals and 8 books. The topics addressed by research projects at the Center range from the value of the planet's ecosystem services to the ecological impacts of global climate change. The Center is actively involved in developing a Knowledge Network for Biocomplexity (knb.ecoinformatics.org) involving information management tools for access to ecological data, which are highly dispersed and heterogeneous. The research and implementation involves developing a desktop data management system for individuals researchers and research groups. Embedded in the system would be capabilities for developing metadata (data about data), making both the metadata and raw data available to the broad community interested in such information, and data query tools (knb.ecoinformatics.org).

  9. U.S. Naval Observatory VLBI Analysis Center

    Science.gov (United States)

    Boboltz, David A.; Fey, Alan L.; Geiger, Nicole; Dieck, Chris; Hall, David M.

    2013-01-01

    This report summarizes the activities of the VLBI Analysis Center at the United States Naval Observatory for the 2012 calendar year. Over the course of the year, Analysis Center personnel continued analysis and timely submission of IVS-R4 databases for distribution to the IVS. During the 2012 calendar year, the USNO VLBI Analysis Center produced two VLBI global solutions designated as usn2012a and usn2012b. Earth orientation parameters (EOP) based on this solution and updated by the latest diurnal (IVS-R1 and IVS-R4) experiments were routinely submitted to the IVS. Sinex files based upon the bi-weekly 24-hour experiments were also submitted to the IVS. During the 2012 calendar year, Analysis Center personnel continued a program to use the Very Long Baseline Array (VLBA) operated by the NRAO for the purpose of measuring UT1-UTC. Routine daily 1-hour duration Intensive observations were initiated using the VLBA antennas at Pie Town, NM and Mauna Kea, HI. High-speed network connections to these two antennas are now routinely used for electronic transfer of VLBI data over the Internet to a USNO point of presence. A total of 270 VLBA Intensive experiments were observed and electronically transferred to and processed at USNO in 2012.

  10. Spiral analysis-improved clinical utility with center detection.

    Science.gov (United States)

    Wang, Hongzhi; Yu, Qiping; Kurtis, Mónica M; Floyd, Alicia G; Smith, Whitney A; Pullman, Seth L

    2008-06-30

    Spiral analysis is a computerized method that measures human motor performance from handwritten Archimedean spirals. It quantifies normal motor activity, and detects early disease as well as dysfunction in patients with movement disorders. The clinical utility of spiral analysis is based on kinematic and dynamic indices derived from the original spiral trace, which must be detected and transformed into mathematical expressions with great precision. Accurately determining the center of the spiral and reducing spurious low frequency noise caused by center selection error is important to the analysis. Handwritten spirals do not all start at the same point, even when marked on paper, and drawing artifacts are not easily filtered without distortion of the spiral data and corruption of the performance indices. In this report, we describe a method for detecting the optimal spiral center and reducing the unwanted drawing artifacts. To demonstrate overall improvement to spiral analysis, we study the impact of the optimal spiral center detection in different frequency domains separately and find that it notably improves the clinical spiral measurement accuracy in low frequency domains.

  11. Carbon dioxide Information Analysis Center and World Data Center: A for Atmospheric trace gases. Annual progress report, FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    Burtis, M.D. [comp.] [Tennessee Univ., Knoxville, TN (United States). Energy, Environment and Resources Center; Cushman, R.M.; Boden, T.A.; Jones, S.B.; Nelson, T.R.; Stoss, F.W. [Oak Ridge National Lab., TN (United States)

    1995-03-01

    This report summarizes the activities and accomplishments made by the Carbon Dioxide Information Analysis Center and World Data Center-A for Atmospheric Trace Gases during the fiscal year 1994. Topics discussed in this report include; organization and staff, user services, systems, communications, Collaborative efforts with China, networking, ocean data and activities of the World Data Center-A.

  12. Evaluation of DoD Information Analysis Centers Program: Representative Sample Study - Benefits to DoD from Use of DoD Information Analysis Centers

    Science.gov (United States)

    1990-06-01

    Defense Electronics Supply Center L. CoL Donald Haverkamp, Defense Electronics Supply Center Ms. Sara Williams , Defense Electronics Supply Center and...Kaman Sciences Corporation Dr. Cho-Yen Ho, Director P. O. Box 120 HTMIAC/ CINDAS Utica, NY 13503 Purdue University (315) 336-0937 2595 Yeager Road FAX...COMPOSITES RELIABILITY ANALYSIS CENTER INFORMATION ANALYSIS (RAC) CENTER (MMCIAC) Steven J. Flint, Technical Director Mr. William McNamara, Director

  13. Analysis on Failure Mode Severity of Machining Center Spindle System

    Institute of Scientific and Technical Information of China (English)

    Guixiang Shen; Shuguang Sun; Yingzhi Zhang; Xiaoyan Qi; Bingkun Chen

    2015-01-01

    According to the subjectivity and fuzziness of analysis on failure mode severity about spindle system of machining center, an analysis model of the failure mode severity of such a system is proposed based on the new fault severity index system, improved analytic hierarchy process ( IAHP ) and entropy⁃based fuzzy comprehensive evaluation. IAHP and entropy methods are adopted to determine the comprehensive failure severity index weight. The evaluation result is obtained after the factor set, comment set, weight set, and other parameters are determined, and then the level of risk degree and numerical value order of every spindle system failure mode is given. By taking an example, we verify that the proposed method can quantify the qualitative problem comprehensively, obtain more accurate analysis results, and provide the theoretical reference for mechanization and sequencing of failure mode effect analysis in reliability analysis. The calculation results can also serve as the basis of failure mode, effects, and criticality analysis in the subsequent step.

  14. Structural Analysis Peer Review for the Static Display of the Orbiter Atlantis at the Kennedy Space Center Visitors Center

    Science.gov (United States)

    Minute, Stephen A.

    2013-01-01

    Mr. Christopher Miller with the Kennedy Space Center (KSC) NASA Safety & Mission Assurance (S&MA) office requested the NASA Engineering and Safety Center's (NESC) technical support on March 15, 2012, to review and make recommendations on the structural analysis being performed for the Orbiter Atlantis static display at the KSC Visitor Center. The principal focus of the assessment was to review the engineering firm's structural analysis for lifting and aligning the orbiter and its static display configuration

  15. Electron transfer pathway analysis in bacterial photosynthetic reaction center

    CERN Document Server

    Kitoh-Nishioka, Hirotaka

    2016-01-01

    A new computational scheme to analyze electron transfer (ET) pathways in large biomolecules is presented with applications to ETs in bacterial photosynthetic reaction center. It consists of a linear combination of fragment molecular orbitals and an electron tunneling current analysis, which enables an efficient first-principles analysis of ET pathways in large biomolecules. The scheme has been applied to the ET from menaquinone to ubiquinone via nonheme iron complex in bacterial photosynthetic reaction center. It has revealed that not only the central Fe$^{2+}$ ion but also particular histidine ligands are involved in the ET pathways in such a way to mitigate perturbations that can be caused by metal ion substitution and depletion, which elucidates the experimentally observed insensitivity of the ET rate to these perturbations.

  16. A Data Analysis Center for Electromagnetic and Hadronic Interaction

    Energy Technology Data Exchange (ETDEWEB)

    Briscoe, William John [George Washington Univ., Washington, DC (United States). Inst. for Nuclear Studies; Strakovsky, Igor I. [George Washington Univ., Washington, DC (United States). Inst. for Nuclear Studies; Workman, Ronald L. [George Washington Univ., Washington, DC (United States). Inst. for Nuclear Studies

    2015-05-31

    The GW Data Analysis Center (DAC) has made significant progress in its program to enhance and expand the partial-wave and multipole analyses of fundamental reactions, while maintaining and expanding each associated database. These efforts provide guidance to national and international experimental and theoretical efforts, and are an important link between theory and experiment. Our principal goals are focused on baryon and meson physics programs and related topics.

  17. Non-linguistic analysis of call center conversations

    CERN Document Server

    Kopparapu, Sunil Kumar

    2014-01-01

    The book focuses on the part of the audio conversation not related to language such as speaking rate (in terms of number of syllables per unit time) and emotion centric features. This text examines using non-linguistics features to infer information from phone calls to call centers. The author analyzes 'how' the conversation happens and not 'what' the conversation is about by audio signal processing and analysis.

  18. SWOT analysis in Sina Trauma and Surgery Research Center.

    Science.gov (United States)

    Salamati, Payman; ashraf Eghbali, Ali; Zarghampour, Manijeh

    2014-01-01

    The present study was conducted with the aim of identifying and evaluating the internal and external factors, affecting the Sina Trauma and Surgery Research Center, affiliated to Tehran University of Medical Sciences and propose some of related strategies to senior managers. We used a combined quantitative and qualitative methodology. Our study population consisted of personnel (18 individuals) at Sina Trauma and Surgery Research Center. Data-collection tools were the group discussions and the questionnaires. Data were analyzed with descriptive statistics and SWOT (Strength, Weakness, Opportunities and Threats) analysis. 18 individuals participated in sessions, consisting of 8 women (44.4%) and 10 men (55.6%). The final scores were 2.45 for internal factors (strength-weakness) and 2.17 for external factors (opportunities-threats). In this study, we proposed 36 strategies (10 weakness-threat strategies, 10 weakness-opportunity strategies, 7 strength-threat strategies, and 9 strength-opportunity strategies). The current status of Sina Trauma and Surgery Research Center is threatened weak. We recommend the center to implement the proposed strategies.

  19. SWOT analysis in Sina Trauma and Surgery Research Center.

    Directory of Open Access Journals (Sweden)

    Payman Salamati

    2014-02-01

    Full Text Available The present study was conducted with the aim of identifying and evaluating the internal and external factors, affecting the Sina Trauma and Surgery Research Center, affiliated to Tehran University of Medical Sciences and propose some of related strategies to senior managers. We used a combined quantitative and qualitative methodology. Our study population consisted of personnel (18 individuals at Sina Trauma and Surgery Research Center. Data-collection tools were the group discussions and the questionnaires. Data were analyzed with descriptive statistics and SWOT (Strength, Weakness, Opportunities and Threats analysis. 18 individuals participated in sessions, consisting of 8 women (44.4% and 10 men (55.6%. The final scores were 2.45 for internal factors (strength-weakness and 2.17 for external factors (opportunities-threats. In this study, we proposed 36 strategies (10 weakness-threat strategies, 10 weakness-opportunity strategies, 7 strength-threat strategies, and 9 strength-opportunity strategies. The current status of Sina Trauma and Surgery Research Center is threatened weak. We recommend the center to implement the proposed strategies.

  20. Convective Weather Forecast Accuracy Analysis at Center and Sector Levels

    Science.gov (United States)

    Wang, Yao; Sridhar, Banavar

    2010-01-01

    This paper presents a detailed convective forecast accuracy analysis at center and sector levels. The study is aimed to provide more meaningful forecast verification measures to aviation community, as well as to obtain useful information leading to the improvements in the weather translation capacity models. In general, the vast majority of forecast verification efforts over past decades have been on the calculation of traditional standard verification measure scores over forecast and observation data analyses onto grids. These verification measures based on the binary classification have been applied in quality assurance of weather forecast products at the national level for many years. Our research focuses on the forecast at the center and sector levels. We calculate the standard forecast verification measure scores for en-route air traffic centers and sectors first, followed by conducting the forecast validation analysis and related verification measures for weather intensities and locations at centers and sectors levels. An approach to improve the prediction of sector weather coverage by multiple sector forecasts is then developed. The weather severe intensity assessment was carried out by using the correlations between forecast and actual weather observation airspace coverage. The weather forecast accuracy on horizontal location was assessed by examining the forecast errors. The improvement in prediction of weather coverage was determined by the correlation between actual sector weather coverage and prediction. observed and forecasted Convective Weather Avoidance Model (CWAM) data collected from June to September in 2007. CWAM zero-minute forecast data with aircraft avoidance probability of 60% and 80% are used as the actual weather observation. All forecast measurements are based on 30-minute, 60- minute, 90-minute, and 120-minute forecasts with the same avoidance probabilities. The forecast accuracy analysis for times under one-hour showed that the errors in

  1. Estimation procedures affect the center of pressure frequency analysis.

    Science.gov (United States)

    Vieira, T M M; Oliveira, L F; Nadal, J

    2009-07-01

    Even though frequency analysis of body sway is widely applied in clinical studies, the lack of standardized procedures concerning power spectrum estimation may provide unreliable descriptors. Stabilometric tests were applied to 35 subjects (20-51 years, 54-95 kg, 1.6-1.9 m) and the power spectral density function was estimated for the anterior-posterior center of pressure time series. The median frequency was compared between power spectra estimated according to signal partitioning, sampling rate, test duration, and detrending methods. The median frequency reliability for different test durations was assessed using the intraclass correlation coefficient. When increasing number of segments, shortening test duration or applying linear detrending, the median frequency values increased significantly up to 137%. Even the shortest test duration provided reliable estimates as observed with the intraclass coefficient (0.74-0.89 confidence interval for a single 20-s test). Clinical assessment of balance may benefit from a standardized protocol for center of pressure spectral analysis that provides an adequate relationship between resolution and variance. An algorithm to estimate center of pressure power density spectrum is also proposed.

  2. Estimation procedures affect the center of pressure frequency analysis

    Directory of Open Access Journals (Sweden)

    T.M.M. Vieira

    2009-07-01

    Full Text Available Even though frequency analysis of body sway is widely applied in clinical studies, the lack of standardized procedures concerning power spectrum estimation may provide unreliable descriptors. Stabilometric tests were applied to 35 subjects (20-51 years, 54-95 kg, 1.6-1.9 m and the power spectral density function was estimated for the anterior-posterior center of pressure time series. The median frequency was compared between power spectra estimated according to signal partitioning, sampling rate, test duration, and detrending methods. The median frequency reliability for different test durations was assessed using the intraclass correlation coefficient. When increasing number of segments, shortening test duration or applying linear detrending, the median frequency values increased significantly up to 137%. Even the shortest test duration provided reliable estimates as observed with the intraclass coefficient (0.74-0.89 confidence interval for a single 20-s test. Clinical assessment of balance may benefit from a standardized protocol for center of pressure spectral analysis that provides an adequate relationship between resolution and variance. An algorithm to estimate center of pressure power density spectrum is also proposed.

  3. Analysis of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Wu, Hsi-Yung T.; Shaw, Peter; Przekop, Adam

    2013-01-01

    The hybrid wing body center section test article is an all-composite structure made of crown, floor, keel, bulkhead, and rib panels utilizing the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) design concept. The primary goal of this test article is to prove that PRSEUS components are capable of carrying combined loads that are representative of a hybrid wing body pressure cabin design regime. This paper summarizes the analytical approach, analysis results, and failure predictions of the test article. A global finite element model of composite panels, metallic fittings, mechanical fasteners, and the Combined Loads Test System (COLTS) test fixture was used to conduct linear structural strength and stability analyses to validate the specimen under the most critical combination of bending and pressure loading conditions found in the hybrid wing body pressure cabin. Local detail analyses were also performed at locations with high stress concentrations, at Tee-cap noodle interfaces with surrounding laminates, and at fastener locations with high bearing/bypass loads. Failure predictions for different composite and metallic failure modes were made, and nonlinear analyses were also performed to study the structural response of the test article under combined bending and pressure loading. This large-scale specimen test will be conducted at the COLTS facility at the NASA Langley Research Center.

  4. Analysis of NSTX Upgrade OH Magnet and Center Stack

    Energy Technology Data Exchange (ETDEWEB)

    A. Zolfaghari, P. Titus, J. Chrzanowski, A. Salehzadeh, F. Dahlgren

    2010-11-30

    The new ohmic heating (OH) coil and center stack for the National Spherical Torus Experiment (NSTX) upgrade are required to meet cooling and structural requirements for operation at the enhanced 1 Tesla toroidal field and 2 MA plasma current. The OH coil is designed to be cooled in the time between discharges by water flowing in the center of the coil conductor. We performed resistive heating and thermal hydraulic analyses to optimize coolant channel size to keep the coil temperature below 100 C and meet the required 20 minute cooling time. Coupled electromagnetic, thermal and structural FEA analyses were performed to determine if the OH coil meets the requirements of the structural design criteria. Structural response of the OH coil to its self-field and the field from other coils was analyzed. A model was developed to analyze the thermal and electromagnetic interaction of centerstack components such as the OH coil, TF inner legs and the Bellville washer preload mechanism. Torsional loads from the TF interaction with the OH and poloidal fields are transferred through the TF flag extensions via a torque transfer coupling to the rest of the tokamak structure. A 3D FEA analysis was performed to qualify this design. The results of these analyses, which will be presented in this paper, have led to the design of OH coil and centerstack components that meet the requirements of the NSTX-upgrade structural design criteria.

  5. Environmental Quality Information Analysis Center (EQIAC) operating procedures handbook

    Energy Technology Data Exchange (ETDEWEB)

    Walsh, T.E. (Florida Univ., Gainesville, FL (United States)); Das, S. (Oak Ridge National Lab., TN (United States))

    1992-08-01

    The Operating Procedures Handbook of the Environmental Quality Information Analysis Center (EQIAC) is intended to be kept current as EQIAC develops and evolves. Its purpose is to provide a comprehensive guide to the mission, infrastructure, functions, and operational procedures of EQIAC. The handbook is a training tool for new personnel and a reference manual for existing personnel. The handbook will be distributed throughout EQIAC and maintained in binders containing current dated editions of the individual sections. The handbook will be revised at least annually to reflect the current structure and operational procedures of EQIAC. The EQIAC provides information on environmental issues such as compliance, restoration, and environmental monitoring do the Air Force and DOD contractors.

  6. Environmental Quality Information Analysis Center multi-year plan

    Energy Technology Data Exchange (ETDEWEB)

    Rivera, R.G. [RDG, Inc. (United States); Das, S. [Oak Ridge National Lab., TN (United States); Walsh, T.E. [Florida Univ., Gainesville, FL (United States)

    1992-09-01

    An information analysis center (IAC) is a federal resource that provides technical information for a specific technology field. An IAC links an expert technical staff with an experienced information specialist group, supported by in-house or external data bases to provide technical information and maintain a corporate knowledge in a technical area. An IAC promotes the rapid transfer of technology among its users and provides assistance in adopting new technology and predicting and assessing emerging technology. This document outlines the concept, requirements, and proposed development of an Environmental Quality IAC (EQIAC). An EQIAC network is composed of several nodes, each of which has specific technology capabilities. This document outlines strategic and operational objectives for the phased development of one such node of an EQIAC network.

  7. Survival Analysis of Drug Abuse Relapse in Addiction Treatment Centers

    Directory of Open Access Journals (Sweden)

    Kassani

    2015-09-01

    Full Text Available Background Drug abuse is a chronic and enduring phenomenon, which is among the important challenging public health problems. One of the main aspects in drug abuse is the relapse. Objectives The aims of this study were to estimate the time to relapse (survival rate and to evaluate some of its associated variables by survival analysis. Patients and Methods This research was conducted in four addiction treatment centers on 140 self-referred addicts in Ilam city, Iran, in 2012. Cluster sampling method was used for selecting the samples and data were collected by interview and referring to the subjects’ records. The gathered data were analyzed through the life table, Kaplan-Meier analysis, log rank test, and Cox regression. Results The relapse rate was 30.42%, mean and median of the time to relapse (survival time were 27.40 ± 1.63 months (CI 95%: 24.19 - 30.60 and 25 ± 2.25 months (CI 95%: 22.5 - 27.5, respectively. In the first six months, the cumulative survival rate was 83%, while in the 24th month it was 46% and the following time was consistent. Job status (OR = 2.64, marital status (OR = 1.55, family size (OR = 1.20 and age (OR = 0.23 were statistically significant in Cox regression model. Conclusions In the initial treatment, it seems necessary to supervise and monitor the treatment process through staff in addiction treatment centers together with the company of the addicts’ families to reduce relapse rate.

  8. Carbon Dioxide Analysis Center and World Data Center-A for Atmospheric Trace Gases fiscal year 1997 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Burtis, M.D. [comp.; Cushman, R.M.; Boden, T.A.; Jones, S.B.; Kaiser, D.P.; Nelson, T.R.

    1998-03-01

    Fiscal year (FY) 1997 was another exciting and productive one for the Carbon Dioxide Information Analysis Center (CDIAC) at the Oak Ridge National Laboratory. During FY 1997, CDIAC launched the Quality Systems Science Center for the North American Research Strategy for Tropospheric Ozone (NARSTO). The purpose of NARSTO--a US-Canada-Mexico initiative of government agencies, industry, and the academic research community--is to improve the understanding of the formation and transport of tropospheric ozone.

  9. The Clean Energy Manufacturing Analysis Center (CEMAC): Providing Analysis and Insights on Clean Technology Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Nicholi S [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-28

    The U.S. Department of Energy's Clean Energy Manufacturing Analysis Center (CEMAC) provides objective analysis and up-to-date data on global supply chains and manufacturing of clean energy technologies. Policymakers and industry leaders seek CEMAC insights to inform choices to promote economic growth and the transition to a clean energy economy.

  10. Data acquisition and analysis at the Structural Biology Center

    Energy Technology Data Exchange (ETDEWEB)

    Westbrook, M.L.; Coleman, T.A.; Daly, R.T. [Argonne National Lab., IL (United States); Pflugrath, J.W. [Molecular Structure Corp., The Woodlands, TX (United States)

    1996-12-31

    The Structural Biology Center (SBC), a national user facility for macromolecular crystallography located at Argonne National Laboratory`s Advanced Photon Source, is currently being built and commissioned. SBC facilities include a bending-magnet beamline, an insertion-device beamline, laboratory and office space adjacent to the beamlines, and associated instrumentation, experimental apparatus, and facilities. SBC technical facilities will support anomalous dispersion phasing experiments, data collection from microcrystals, data collection from crystals with large molecular structures and rapid data collection from multiple related crystal structures for protein engineering and drug design. The SBC Computing Systems and Software Engineering Group is tasked with developing the SBC Control System, which includes computing systems, network, and software. The emphasis of SBC Control System development has been to provide efficient and convenient beamline control, data acquisition, and data analysis for maximal facility and experimenter productivity. This paper describes the SBC Control System development, specifically data acquisition and analysis at the SBC, and the development methods used to meet this goal.

  11. Carbon Dioxide Information Analysis Center: FY 1991 activities

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M.; Stoss, F.W.

    1992-06-01

    During the course of a fiscal year, Oak Ridge National Laboratory's Carbon Dioxide Information Analysis Center (CDIAC) distributes thousands of specially publications-numeric data packages (NDPs), computer model packages (CMPs), technical reports, public communication publications, newsletters, article reprints, and reference books-in response to requests for information related to global environmental issues, primarily those pertaining to climate change. CDIAC's staff also provides technical responses to specific inquiries related to carbon dioxide (CO{sub 2}), other trace gases, and climate. Hundreds of referrals to other researchers, policy analysts, information specialists, or organizations are also facilitated by CDIAC's staff. This report provides an account of the activities accomplished by CDIAC during the period October 1, 1990 to September 30, 1991. An organizational overview of CDIAC and its staff is supplemented by a detailed description of inquiries received and CDIAC's response to those inquiries. An analysis and description of the preparation and distribution of numeric data packages, computer model packages, technical reports, newsletters, factsheets, specially publications, and reprints is provided. Comments and descriptions of CDIAC's information management systems, professional networking, and special bilateral agreements are also described.

  12. Carbon Dioxide Information Analysis Center: FY 1991 activities

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M.; Stoss, F.W.

    1992-06-01

    During the course of a fiscal year, Oak Ridge National Laboratory`s Carbon Dioxide Information Analysis Center (CDIAC) distributes thousands of specially publications-numeric data packages (NDPs), computer model packages (CMPs), technical reports, public communication publications, newsletters, article reprints, and reference books-in response to requests for information related to global environmental issues, primarily those pertaining to climate change. CDIAC`s staff also provides technical responses to specific inquiries related to carbon dioxide (CO{sub 2}), other trace gases, and climate. Hundreds of referrals to other researchers, policy analysts, information specialists, or organizations are also facilitated by CDIAC`s staff. This report provides an account of the activities accomplished by CDIAC during the period October 1, 1990 to September 30, 1991. An organizational overview of CDIAC and its staff is supplemented by a detailed description of inquiries received and CDIAC`s response to those inquiries. An analysis and description of the preparation and distribution of numeric data packages, computer model packages, technical reports, newsletters, factsheets, specially publications, and reprints is provided. Comments and descriptions of CDIAC`s information management systems, professional networking, and special bilateral agreements are also described.

  13. Carbon Dioxide Information Analysis Center: FY 1992 activities

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M. [Oak Ridge National Lab., TN (United States). Carbon Dioxide Information Analysis Center; Stoss, F.W. [Tennessee Univ., Knoxville, TN (United States). Energy, Environment and Resources Center

    1993-03-01

    During the course of a fiscal year, Oak Ridge National Laboratory`s Carbon Dioxide Information Analysis Center (CDIAC) distributes thousands of specialty publications-numeric data packages (NDPs), computer model packages (CMPs), technical reports, public communication publications, newsletters, article reprints, and reference books-in response to requests for information related to global environmental issues, primarily those pertaining to climate change. CDIACs staff also provides technical responses to specific inquiries related to carbon dioxide (CO{sub 2}), other trace gases, and climate. Hundreds of referrals to other researchers, policy analysts, information specialists, or organizations are also facilitated by CDIAC`s staff. This report provides an account of the activities accomplished by CDIAC during the period October 1, 1991 to September 30, 1992. An organizational overview of CDIAC and its staff is supplemented by a detailed description of inquiries received and CDIAC`s response to those inquiries. As analysis and description of the preparation and distribution of numeric data packages, computer model packages, technical reports, newsletters, fact sheets, specialty publications, and reprints is provided. Comments and descriptions of CDIAC`s information management systems, professional networking, and special bilateral agreements are also described.

  14. Performance of the Carbon Dioxide Information Analysis Center (CDIAC)

    Energy Technology Data Exchange (ETDEWEB)

    Stoss, F.W. [Univ. of Tennessee, Knoxville, TN (United States). Environment, Energy, and Resources Center; Jones, S.B. [Oak Ridge National Lab., TN (United States)

    1993-11-01

    The Carbon Dioxide Information Analysis Center (CDIAC) provides information and data resources in support of the US Department of Energy`s Global Change Research Program. CDIAC also serves as a resource of global change information for a broader international commonly of researchers, policymakers, managers, educators, and students. The number of requests for CDIAC`s data products, information services, and publications has grown over the years and represents multidisciplinary interests in the physical, life, and social sciences and from diverse work settings in government, business, and academia. CDIAC`s staff addresses thousands of requests yearly for data and information resources. In response to these requests, CDIAC has distributed tens of thousands of data products, technical reports, newsletters, and other information resources worldwide since 1982. This paper describes CDIAC, examines CDIAC`s user community, and describes CDIAC`s response to requests for information. The CDIAC Information System, which serves as a comprehensive PC-based inventory and information management tracking system, is also described.

  15. Centers of structures in electromagnetism--a critical analysis

    DEFF Research Database (Denmark)

    Appel-Hansen, Jørgen

    1982-01-01

    Some principles for finding reference points or centers of structures in electromagnetism are outlined. It is pointed out that the centers which are found depend on arbitrary choices. Since some of the principles are based on Friis's transmission formula and the radar equation, these are given...

  16. Oregon High Desert Interpretive Center : Economic feasibility and impact analysis

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is a proposal to construct a High Desert Interpretive Center to inform visitors to Harney County, Oregon of the opportunities for education, recreation and...

  17. Carbon Dioxide Information Analysis Center and World Data Center for Atmospheric Trace Gases Fiscal Year 2000 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M.

    2001-11-15

    The Carbon Dioxide Information Analysis Center (CDIAC), which includes the World Data Center (WDC) for Atmospheric Trace Gases, is the primary global change data and information analysis center of the U.S. Department of Energy (DOE). More than just an archive of data sets and publications, CDIAC has, since its inception in 1982, enhanced the value of its holdings through intensive quality assurance, documentation, and integration. Whereas many traditional data centers are discipline-based (for example, meteorology or oceanography), CDIAC's scope includes potentially anything and everything that would be of value to users concerned with the greenhouse effect and global climate change, including concentrations of carbon dioxide (CO{sub 2}) and other radiatively active gases in the atmosphere; the role of the terrestrial biosphere and the oceans in the biogeochemical cycles of greenhouse gases; emissions of CO{sub 2} and other trace gases to the atmosphere; long-term climate trends; the effects of elevated CO{sub 2} on vegetation; and the vulnerability of coastal areas to rising sea levels.

  18. Carbon Dioxide Information Analysis Center and World Data Center for Atmospheric Trace Gases, Fiscal Year 2002 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M.

    2003-08-28

    The Carbon Dioxide Information Analysis Center (CDIAC), which includes the World Data Center (WDC) for Atmospheric Trace Gases, is the primary global change data and information analysis center of the U.S. Department of Energy (DOE). More than just an archive of data sets and publications, CDIAC has, since its inception in 1982, enhanced the value of its holdings through intensive quality assurance, documentation, and integration. Whereas many traditional data centers are discipline-based (for example, meteorology or oceanography), CDIAC's scope includes potentially anything and everything that would be of value to users concerned with the greenhouse effect and global climate change, including atmospheric concentrations and atmospheric emissions of carbon dioxide (CO{sub 2}) and other radiatively active gases; the role of the terrestrial biosphere and the oceans in the biogeochemical cycles of greenhouse gases; long-term climate trends; the effects of elevated CO{sub 2} on vegetation; and the vulnerability of coastal areas to rising sea levels.

  19. Analysis of TCP performance in data center networks

    CERN Document Server

    Kulkarni, Santosh

    2014-01-01

    This book addresses the need to improve TCP’s performance inside data centers by providing solutions that are both practical and backward compatible with standard TCP versions. The authors approach this challenge first by deriving an analytical model for TCP’s performance under typical data center workload traffic.  They then discuss some solutions that are designed to improve TCP performance by either proactively detecting network congestion through probabilistic retransmission or by avoiding timeout penalty through dynamic resizing of TCP segments. Experimental results show that each of techniques discussed outperforms standard TCP inside a data center.  ·         Analyzes the reasons behind TCP performance slump inside data centers when operating under synchronized workload traffic; ·         Introduces solutions to TCP performance slump inside data centers that are both practical and backward compatible; ·         Describes mechanisms that are responsible for TCP’s relia...

  20. Development and analysis of superconductors with projected nanostructured pinning centers

    Science.gov (United States)

    Rodrigues, Carlos A.; Rodrigues, D.

    2004-08-01

    The present work has the main objective to study the influence of the proximity effect on the superconducting properties of materials with pinning center dimensions comparable to the coherence length. Artificial Pinning Centers (APC) of Cu(Sn) were introduced into the Nb 3Sn superconducting phase using successive bundlings followed by swaging and wire drawing. Three superconductor wires were produced using the internal tin method. After fabrication, the samples were heat treated to optimize the superconducting phase formation. Microstructural and superconducting characterization of the samples were realized. The results showed the influence of the proximity effect on Tc, Jc and Bc2.

  1. Analysis and design of residential load centers. Volume 2: Appendices

    Science.gov (United States)

    Mehalick, E. M.; Lamders, R.; Obrien, G.; Tully, G. F.; Parker, J.

    1982-03-01

    These three appendices present information on residential load center classification information. Emphasis is given to: residential development trends and residential housing classifications; detached house site layout alternatives; and legal and institional issues, including condominium ownership, commercial ownership of photovoltaic systems in mobile homes, and utility ownership of photovoltaic systems.

  2. Directory of Federally Supported Information Analysis Centers, 1979. Fourth Edition.

    Science.gov (United States)

    1979-01-01

    controlled by (DASIAC) Headquarters, DNA . General Electric Tempo 816 State St. SERVICES: Provides consulting and advisory Santa Barbara, Calif. 93102...makes materials available to qualified users; assists in organizing, announcing, and conducting SPONSOR: Defense Nuclear Agency ( DNA ). seminars...and Greenland flora; Antarctic lichen mission to visit the Center should be addressed to and plant fossil collections. the Security Office of the

  3. Analysis of good practice of Public Health Emergency Operations Centers

    Institute of Scientific and Technical Information of China (English)

    Min Xu; Shi-Xue Li

    2015-01-01

    Objective:To study the public health Emergency Operations Centers (EOCs)in the US, the European Union, the UK and Australia, and summarize the good practice for the improvement of National Health Emergency Response Command Center in Chinese National Health and Family Planning Commission.Methods:Literature review was conducted to explore the EOCs of selected countries.Results:The study focused on EOC function, organizational structure, human resources and information management. The selected EOCs had the basic EOC functions of coordinating and commanding as well as the public health related functions such as monitoring the situation, risk assessment, and epidemiological briefings. The organizational structures of the EOCs were standardized, scalable and flexible. Incident Command System was the widely applied organizational structure with a strong preference. The EOCs were managed by a unit of emergency management during routine time and surge staff were engaged upon emergencies. The selected EOCs had clear information management framework including information collection, assessment and dissemination.Conclusions:The performance of National Health Emergency Response Command Center can be improved by learning from the good practice of the selected EOCs, including setting clear functions, standardizing the organizational structure, enhancing the human resource capacity and strengthening information management.

  4. [Location of radiotherapy centers: an exploratory geographic analysis for Belgium].

    Science.gov (United States)

    Cotteels, C; Peeters, D; Coucke, P A; Thomas, I

    2012-10-01

    The distance between the patient's home and a radiotherapy department may represent a hurdle for the patient and influence treatment choice. Therefore, it is necessary to check whether the geographical distribution of radiotherapy centers is in accordance with cancer incidence, taking also into account the cost of travelling to the radiotherapy department. The objective of this study is double; first, to map the current locations of radiotherapy centers across the country and second, to evaluate the observed spatial disparities with appropriate tools. A model of operational research (P-median) is used to suggest the optimal locations and allocations and to compare them with the current situation. This is an exploratory study with simple inputs. It helps to better understand the current geographical distribution of radiotherapy centers in Belgium as well as its possible limitations. RESULTS-CONCLUSION: It appears that the current situation is on the average acceptable in terms of accessibility to the service and that the method presents huge potentialities for decision making so as to yield a spatial system that is both efficient and equitable. Copyright © 2012 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

  5. A Partial Swot Analysis of the Turkish Bank Call Centers: The Actual and the Assumed Weaknesses

    OpenAIRE

    ÖZKAN, Ahmet Hakan

    2011-01-01

    The bank call centers of Turkey are seen as a tool of perceiving the threats and evaluating opportunities in the SWOT analysis. By the way they are evaluated as a factor of strength. However, the weaknesses of the call centers which must be taken into account in a SWOT analysis, are so various that they cannot be ignored. The weaknesses of the call centers are elaborated with this research. The ways the call centers harm the corporations or the ways they might harm are revised.

  6. Staff roster for 1979: National Center for Analysis of Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    This publication is a compilation of resumes from the current staff of the National Center for Analysis of Energy Systems. The Center, founded in January 1976, is one of four areas within the Department of Energy and Environment at Brookhaven National Laboratory. The emphasis of programs at the Center is on energy policy and planning studies at the regional, national, and international levels, involving quantitative, interdisciplinary studies of the technological, economic, social, and environmental aspects of energy systems. To perform these studies the Center has assembled a staff of experts in the areas of science, technology, economics planning, health and safety, information systems, and quantitative analysis.

  7. Tri-Center Analysis: Determining Measures of Trichotomous Central Tendency for the Parametric Analysis of Tri-Squared Test Results

    Science.gov (United States)

    Osler, James Edward

    2014-01-01

    This monograph provides an epistemological rational for the design of a novel post hoc statistical measure called "Tri-Center Analysis". This new statistic is designed to analyze the post hoc outcomes of the Tri-Squared Test. In Tri-Center Analysis trichotomous parametric inferential parametric statistical measures are calculated from…

  8. DFTCalc: Reliability centered maintenance via fault tree analysis (tool paper)

    NARCIS (Netherlands)

    Guck, Dennis; Spel, Jip; Stoelinga, Mariëlle Ida Antoinette; Butler, Michael; Conchon, Sylvain; Zaïdi, Fatiha

    2015-01-01

    Reliability, availability, maintenance and safety (RAMS) analysis is essential in the evaluation of safety critical systems like nuclear power plants and the railway infrastructure. A widely used methodology within RAMS analysis are fault trees, representing failure propagations throughout a system.

  9. DFTCalc: reliability centered maintenance via fault tree analysis (tool paper)

    NARCIS (Netherlands)

    Guck, Dennis; Spel, Jip; Stoelinga, Mariëlle; Butler, Michael; Conchon, Sylvain; Zaïdi, Fatiha

    2015-01-01

    Reliability, availability, maintenance and safety (RAMS) analysis is essential in the evaluation of safety critical systems like nuclear power plants and the railway infrastructure. A widely used methodology within RAMS analysis are fault trees, representing failure propagations throughout a system.

  10. PHASE ANALYSIS AS A TOOL OF PREESTIMATED ANALYSIS OF THE ACTIVITY OF A MULTIFUNCTIONAL CENTER

    Directory of Open Access Journals (Sweden)

    Kovaleva K. A.

    2015-03-01

    Full Text Available The article is devoted to the phase analysis as a tool preprocessor analysis of a multi-purpose center. Consider the time series of the daily number of requests received on the basis of the phase portraits of these time series. These time series have strong properties of cycles and periodicity. Practice has shown that in modern conditions, for example, for the Russian economy with its instability and financial crises, classical economic theory and statistics, built on linear models, turned out to be unproductive. Overview of approaches and economic-mathematical methods preprocessor analysis of evolutionary economic processes and the corresponding time series allows concluding the following: one versatile, satisfying all the requirements, do not possess the shortcomings of the method of analysis and forecasting does not exist. Each approach and each method has its advantages, disadvantages, limits of use. Most of the known methods of forecasting operate detected in the considered time series properties of cycles and periodicity. Thus, the mere presence of a pronounced cyclicity at different levels of the considered hierarchical model of the time series of the number of requests in a multi-purpose center are important indicators of the possibility of constructing an adequate predictive model number of requests in the multi-purpose centre

  11. Multi-center analysis of glucocerebrosidase mutations in Parkinson disease

    Science.gov (United States)

    Sidransky, Ellen; Nalls, Michael A.; Aasly, Jan O.; Aharon-Peretz, Judith; Annesi, Grazia; Barbosa, Egberto Reis; Bar-Shira, Anat; Berg, Daniela; Bras, Jose; Brice, Alexis; Chen, Chiung-Mei; Clark, Lorraine N.; Condroyer, Christel; De Marco, Elvira Valeria; Dürr, Alexandra; Eblan, Michael J.; Fahn, Stanley; Farrer, Matthew; Fung, Hon-Chung; Gan-Or, Ziv; Gasser, Thomas; Gershoni-Baruch, Ruth; Giladi, Nir; Griffith, Alida; Gurevich, Tanya; Januario, Cristina; Kropp, Peter; Lang, Anthony E.; Lee-Chen, Guey-Jen; Lesage, Suzanne; Marder, Karen; Mata, Ignacio F.; Mirelman, Anat; Mitsui, Jun; Mizuta, Ikuko; Nicoletti, Giuseppe; Oliveira, Catarina; Ottman, Ruth; Orr-Urtreger, Avi; Pereira, Lygia V.; Quattrone, Aldo; Rogaeva, Ekaterina; Rolfs, Arndt; Rosenbaum, Hanna; Rozenberg, Roberto; Samii, Ali; Samaddar, Ted; Schulte, Claudia; Sharma, Manu; Singleton, Andrew; Spitz, Mariana; Tan, Eng-King; Tayebi, Nahid; Toda, Tatsushi; Troiano, André; Tsuji, Shoji; Wittstock, Matthias; Wolfsberg, Tyra G.; Wu, Yih-Ru; Zabetian, Cyrus P.; Zhao, Yi; Ziegler, Shira G.

    2010-01-01

    Background Recent studies indicate an increased frequency of mutations in the gene for Gaucher disease, glucocerebrosidase (GBA), among patients with Parkinson disease. An international collaborative study was conducted to ascertain the frequency of GBA mutations in ethnically diverse patients with Parkinson disease. Methods Sixteen centers participated, including five from the Americas, six from Europe, two from Israel and three from Asia. Each received a standard DNA panel to compare genotyping results. Genotypes and phenotypic data from patients and controls were analyzed using multivariate logistic regression models and the Mantel Haenszel procedure to estimate odds ratios (ORs) across studies. The sample included 5691 patients (780 Ashkenazi Jews) and 4898 controls (387 Ashkenazi Jews). Results All 16 centers could detect GBA mutations, L444P and N370S, and the two were found in 15.3% of Ashkenazi patients with Parkinson disease (ORs = 4.95 for L444P and 5.62 for N370S), and in 3.2% of non-Ashkenazi patients (ORs = 9.68 for L444P and 3.30 for N370S). GBA was sequenced in 1642 non-Ashkenazi subjects, yielding a frequency of 6.9% for all mutations, demonstrate that limited mutation screens miss half the mutant alleles. The presence of any GBA mutation was associated with an OR of 5.43 across studies. Clinically, although phenotypes varied, subjects with a GBA mutation presented earlier, and were more likely to have affected relatives and atypical manifestations. Conclusion Data collected from sixteen centers demonstrate that there is a strong association between GBA mutations and Parkinson disease. PMID:19846850

  12. Management and performance features of cancer centers in Europe: A fuzzy-set analysis

    NARCIS (Netherlands)

    Wind, Anke; Lobo, Mariana Fernandes; van Dijk, Joris; Lepage-Nefkens, Isabelle; Laranja-Pontes, Jose; da Conceicao Goncalves, Vitor; van Harten, Willem H.; Rocha-Goncalves, Francisco Nuno

    2016-01-01

    The specific aim of this study is to identify the performance features of cancer centers in the European Union by using a fuzzy-set qualitative comparative analysis (fsQCA). The fsQCA method represents cases (cancer centers) as a combination of explanatory and outcome conditions. This study uses

  13. A Management Review and Analysis of Purdue University Libraries and Audio-Visual Center.

    Science.gov (United States)

    Baaske, Jan; And Others

    A management review and analysis was conducted by the staff of the libraries and audio-visual center of Purdue University. Not only were the study team and the eight task forces drawn from all levels of the libraries and audio-visual center staff, but a systematic effort was sustained through inquiries, draft reports and open meetings to involve…

  14. Carbon Dioxide Information Analysis Center and World Data Center-A for atmospheric trace gases: FY 1993 activities

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M. [Oak Ridge National Lab., TN (United States). Carbon Dioxide Information Analysis Center; Stoss, F.W. [Oak Ridge National Lab., TN (United States). Carbon Dioxide Information Analysis Center]|[Univ. of Tennessee, Knoxville, TN (United States). Energy, Environment, and Resources Center

    1994-01-01

    During the course of a fiscal year, Oak Ridge National Laboratory`s Carbon Dioxide Information Analysis Center (CDIAC) distributes thousands of specialty publications-numeric data packages (NDPs), computer model packages (CMPs), technical reports, public communication publications, newsletters, article reprints, and reference books-in response to requests for information related to global environmental issues, primarily those pertaining to climate change. CDIAC`s staff also provide technical responses to specific inquiries related to carbon dioxide (CO{sub 2}), other trace gases, and climate. Hundreds of referrals to other researchers, policy analysts, information specialists, or organizations are also facilitated by CDIAC`s staff. This report provides an account of the activities accomplished by CDIAC (including World Data Center-A for Atmospheric Trace Gases) during the period October 1, 1992, to September 30, 1993. An organizational overview of CDIAC and its staff is supplemented by a detailed description of inquiries received and CDIAC`s response to those inquiries. An analysis and description of the preparation and distribution of NDPS, CMPS, technical reports, newsletters, fact sheets, specialty publications, and reprints are provided. Comments and descriptions of CDIAC`s information management systems, professional networking, and special bilateral agreements are also presented.

  15. Cost-Benefit Analysis of Radiation Therapy Services at Tripler Army Medical Center

    National Research Council Canada - National Science Library

    Diehl, Diane S

    2004-01-01

    The purpose of this analysis was to examine the costs and benefits associated with continuance of "in-house" radiation therapy services to eligible beneficiaries at Tripler Army Medical Center (TAMC...

  16. Information Analysis Centers in the Department of Defense. Revision

    Science.gov (United States)

    1987-07-01

    electric rockets, ramjets, space vehicles and gun propulsion systems. This includes chemical synthesis; thermochemistry ; combustion phenomena; physical...equipment testability, and worst case analysis and currently teaches over 1000 government/industry personnel each year. RAC is recognized as a leading

  17. Convention Center Management: A Systems Analysis & Design Course Project

    Science.gov (United States)

    Guidry, Brandi N.; Totaro, Michael W.

    2011-01-01

    A challenge faced by many instructors of systems analysis and design courses is the selection or development of projects that provide challenging, yet suitable, learning experiences for the students. Employing a system development project case in undergraduate MIS courses offers students a multitude of opportunities to experientially examine…

  18. Clean Energy Manufacturing Analysis Center Benchmark Report: Framework and Methodologies

    Energy Technology Data Exchange (ETDEWEB)

    Sandor, Debra [National Renewable Energy Lab. (NREL), Golden, CO (United States); Chung, Donald [National Renewable Energy Lab. (NREL), Golden, CO (United States); Keyser, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mann, Margaret [National Renewable Energy Lab. (NREL), Golden, CO (United States); Engel-Cox, Jill [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-05-23

    This report documents the CEMAC methodologies for developing and reporting annual global clean energy manufacturing benchmarks. The report reviews previously published manufacturing benchmark reports and foundational data, establishes a framework for benchmarking clean energy technologies, describes the CEMAC benchmark analysis methodologies, and describes the application of the methodologies to the manufacturing of four specific clean energy technologies.

  19. Center for Analysis of Heterogeneous and Nonlinear Media

    Science.gov (United States)

    1989-10-14

    computation of singular solutions of the nonlinear Schroedinger equation) Xue Xin (nonlinear homogenization) Jing-Yi Zhu (Ph.D. 1989, adaptive vortex method...numerical analysis of the vortex method for vortex sheets were carried out by Krasny and by Caflisch and Lowengrub. 2. Exact singular solutions of the...restriction to analytic functions. - 18- Singularities - Examples and the Generic Form of Singularities Singular solutions of the Birkhoff-Rott equation (1

  20. Analysis of Convective Weather Impact on Pre-Departure Routing of Flights from Fort Worth Center to New York Center

    Science.gov (United States)

    Arneson, Heather; Bombelli, Alessandro; Segarra-Torne, Adria; Tse, Elmer

    2017-01-01

    In response to severe weather conditions, Traffic Managers specify flow constraints and reroutes to route air traffic around affected regions of airspace. Providing analysis and recommendations of available reroute options and associated airspace capacities would assist Traffic Managers in making more efficient decisions in response to convective weather. These recommendations can be developed by examining historical data to determine which previous reroute options were used in similar weather and traffic conditions. This paper describes the initial steps and methodology used towards this goal. The focus of this work is flights departing from Fort Worth Center destined for New York Center. Dominant routing structures used in the absence of convective weather are identified. A method to extract relevant features from the large volume of weather data available to quantify the impact of convective weather on this routing structure over a given time range is presented. Finally, a method of estimating flow rate capacity along commonly used routes during convective weather events is described. Results show that the flow rates drop exponentially as a function of the values of the proposed feature and that convective weather on the final third of the route was found to have a greater impact on the flow rate restriction than other portions of the route.

  1. Center of attention: A network text analysis of American Sniper

    Directory of Open Access Journals (Sweden)

    Starling Hunter

    2016-06-01

    Full Text Available Network Text Analysis (NTA is a term used to describe a variety of software - supported methods for modeling texts as networks of concepts. In this study we apply NTA to the screenplay of American Sniper, an Academy Award nominee for Best Adapted Screenplay in 2014. Specifically, we est ablish prior expectations as to the key themes associated with war films. We then empirically test whether words associated with the most influentially - positioned nodes in the network signify themes common to the war - film genre. As predicted, we find tha t words and concepts associated with the least constrained nodes in the text network were significantly more likely to be associated with the war genre and significantly less likely to be associated with genres to which the film did not belong.

  2. Imatinib resistance mutation analysis: experience from a tertiary oncology center

    Directory of Open Access Journals (Sweden)

    Mallekavu Suresh Babu

    2015-01-01

    Full Text Available Purpose: BCR-ABL kinase domain (KD mutations account for 50-90% of the imatinib resistance observed in patients of CML-chronic phase. In CML-CP patients receiving imatinib first-line, mutation analysis is recommended in case of failure or suboptimal response using European LeukemiaNet (ELN criteria. The present study was carried out at a tertiary oncology centre in south India to assess which mutations accounted for resistance to imatinib among patients of chronic phase CML being treated with imatinib.Methods: This was a retrospective observational study. We analyzed patients who were tested for imatinib resistance mutation in view of suboptimal responses while on imatinib or imatinib failure. Direct sequencing of the BCR-ABL transcript by the Sanger method was used for IRMA testing.Results: Out of 120 tested for IRMA, 36 (30% had detectable mutations. We observed a higher frequency of mutations at amino acids T315, F359 and M351T.Conclusions: Among the patients who were tested for imatinib resistance mutation in view of suboptimal responses while on imatinib or imatinib failure, 30% had IRMA +ve mutations. The high incidence of imatinib resistance in present study may be attributed to the fact that our patients were given higher dose of imatinib (600 mg, if they failed to achieve CCyR at 12 months or CHR at 3 months as they could not afford second generation TKIs.

  3. Carbon Dioxide Information Analysis Center and World Data Center for Atmospheric Trace Gases Fiscal Year 1999 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M.

    2000-03-31

    The Carbon Dioxide Information Analysis Center (CDIAC), which includes the World Data Center (WDC) for Atmospheric Trace Gases, is the primary global-change data and information analysis center of the Department of Energy (DOE). More than just an archive of data sets and publications, CDIAC has--since its inception in 1982--enhanced the value of its holdings through intensive quality assurance, documentation, and integration. Whereas many traditional data centers are discipline-based (for example, meteorology or oceanography), CDIAC's scope includes potentially anything and everything that would be of value to users concerned with the greenhouse effect and global climate change, including concentrations of carbon dioxide (CO{sub 2}) and other radiatively active gases in the atmosphere; the role of the terrestrial biosphere and the oceans in the biogeochemical cycles of greenhouse gases; emissions of CO{sub 2} and other trace gases to the atmosphere; long-term climate trends; the effects of elevated CO{sub 2} on vegetation; and the vulnerability of coastal areas to rising sea level. CDIAC is located within the Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) in Oak Ridge, Tennessee. CDIAC is co-located with ESD researchers investigating global-change topics, such as the global carbon cycle and the effects of carbon dioxide on vegetation. CDIAC staff are also connected with current ORNL research on related topics, such as renewable energy and supercomputing technologies. CDIAC is supported by the Environmental Sciences Division (Jerry Elwood, Acting Director) of DOE's Office of Biological and Environmental Research. CDIAC's FY 1999 budget was 2.2M dollars. CDIAC represents the DOE in the multi-agency Global Change Data and Information System. Bobbi Parra, and Wanda Ferrell on an interim basis, is DOE's Program Manager with responsibility for CDIAC. CDIAC comprises three groups, Global Change Data, Computer Systems, and

  4. Carbon Dioxide Information Analysis Center and World Data Center for Atmospheric Trace Gases Fiscal Year 2001 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M.

    2002-10-15

    The Carbon Dioxide Information Analysis Center (CDIAC), which includes the World Data Center (WDC) for Atmospheric Trace Gases, is the primary global change data and information analysis center of the U.S. Department of Energy (DOE). More than just an archive of data sets and publications, CDIAC has, since its inception in 1982, enhanced the value of its holdings through intensive quality assurance, documentation, and integration. Whereas many traditional data centers are discipline-based (for example, meteorology or oceanography), CDIAC's scope includes potentially anything and everything that would be of value to users concerned with the greenhouse effect and global climate change, including concentrations of carbon dioxide (CO{sub 2}) and other radiatively active gases in the atmosphere; the role of the terrestrial biosphere and the oceans in the biogeochemical cycles of greenhouse gases; emissions of CO{sub 2} and other trace gases to the atmosphere; long-term climate trends; the effects of elevated CO{sub 2} on vegetation; and the vulnerability of coastal areas to rising sea levels. CDIAC is located within the Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) in Oak Ridge, Tennessee. CDIAC is co-located with ESD researchers investigating global-change topics, such as the global carbon cycle and the effects of carbon dioxide on climate and vegetation. CDIAC staff are also connected with current ORNL research on related topics, such as renewable energy and supercomputing technologies. CDIAC is supported by the Environmental Sciences Division (Jerry Elwood, Director) of DOE's Office of Biological and Environmental Research. CDIAC represents DOE in the multi-agency Global Change Data and Information System (GCDIS). Wanda Ferrell is DOE's Program Manager with overall responsibility for CDIAC. Roger Dahlman is responsible for CDIAC's AmeriFlux tasks, and Anna Palmisano for CDIAC's Ocean Data tasks. CDIAC is made

  5. Child-Centered Play Therapy in the Schools: Review and Meta-Analysis

    Science.gov (United States)

    Ray, Dee C.; Armstrong, Stephen A.; Balkin, Richard S.; Jayne, Kimberly M.

    2015-01-01

    The authors conducted a meta-analysis and systematic review that examined 23 studies evaluating the effectiveness of child centered play therapy (CCPT) conducted in elementary schools. Meta-analysis results were explored using a random effects model for mean difference and mean gain effect size estimates. Results revealed statistically significant…

  6. Root canal centering ability of rotary cutting nickel titanium instruments: A meta-analysis

    Directory of Open Access Journals (Sweden)

    Mohan Gundappa

    2014-01-01

    Full Text Available Aim: To systematically review articles on canal centering ability of endodontic rotary cutting Nickel-Titanium (Ni-Ti instruments and subject results to meta-analysis. Materials and Methods: A comprehensive search was initiated on canal centering ability of different rotary cutting Ni-Ti files such as Protaper, Hero Shaper, K3, Mtwo, Race, Wave One by selecting articles published in peer reviewed journals during 1991-2013 using "Pub Med" database. Inclusion and exclusion criteria were established. A data was created by tabulating: Author name, publication year, sample size, number of experimental groups, methods to evaluate canal centering ability, instrument cross section, taper, tip design, rake angle, mean and standard deviation. The data generated was subjected to meta-analysis. Results: Maximum studies were found to be conducted on mesiobuccal canal of mandibular 1 st molar with curvature ranging from 15-60°. The difference in canal centering ability of different rotary cutting Ni-Ti instruments was not statistically significant. Conclusion: All endodontic rotary cutting Ni-Ti instruments are capable of producing centered preparations. Protaper depicted the best centering ability. Computed tomography is an effective method of evaluating canal centering ability.

  7. Annual abstracts of the National Center for Analysis of Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-12-01

    The National Center for Analysis of Energy Systems at Brookhaven has been in operation since January 1976. This 1978 Annual Abstracts report illustrates the scope of activities of the Center involving the integrated analyses of technological, economic, environmental, and social aspects of energy at the regional, national, and international levels. The major ongoing activities of the Center include: analysis of energy-economic relationships; regional energy and environmental policy; comparative health effects of alternative energy systems; technology assessment and energy R and D priorities; development of energy-economic-environmental models and data bases; R and D strategies for the International Energy Agency; and energy technologies for developing countries. The objectives of the Center and major accomplishments of 1978 are described in the Annual Highlights of the National Center for Analysis of Energy Systems, BNL 50969, which also describes the energy data bases and analytical models used in the course of policy analyses. The multi-disciplinary approach used in the Center, and the close interaction with other analytical groups in universities and industry, provides a unique perspective on the energy situation. This is evidenced by the broad range of activities cited in this Annual Abstracts report.

  8. MULTIDISCIPLINARY TEACHING – MSc COURSE ON TEAMWORK AND OPARATION

    DEFF Research Database (Denmark)

    Karlshøj, Jan; Dederichs, Anne

    2011-01-01

    of Denmark. The goal of the course is to provide training in teamwork at the final stage of the engineering education. The course has been carried out twice. It was held by a multidisciplinary team of professors in periods 2008/09, 2009/10 and 20010/2011. Teams of students were subject of a questionnaire...... investigation on collaboration and team work. The study has the following findings. The latest year there has been a special focus on team work and all members tested their role according to Belbin’s theory on teamwork. The work has the following findings: Collaboration was generally good. However the extra...... focus on teamwork did not lead to a improvement of the team work in contrary. The team-structure was generally flat and decisions were mostly made in consensus. It is worthwhile to offer a multidisciplinary course and give engineering students experience in collaboration methods....

  9. The Northwest Indiana Center for Data and Analysis: A Case Study of Academic Library Community Engagement

    Science.gov (United States)

    Sandberg, Scott; Morris, Cele; Sutherland, Timothy

    2013-01-01

    This paper details community engagement activity of an academic library coordinated within a broader university strategic plan. The Anderson Library at Indiana University Northwest (IU-Northwest) supports a service called the Northwest Indiana Center for Data and Analysis. Created in 1996 with funding made available from the Indiana University…

  10. A Financial Ratio Analysis of For-Profit and Non-Profit Rural Referral Centers

    Science.gov (United States)

    McCue, Michael J.; Nayar, Preethy

    2009-01-01

    Context: National financial data show that rural referral center (RRC) hospitals have performed well financially. RRC hospitals' median cash flow margin ratio was 10.04% in 2002 and grew to 11.04% in 2004. Purpose: The aim of this study is to compare the ratio analysis of key operational and financial performance measures of for-profit RRCs to…

  11. Joint Center for Operational Analysis Quarterly Bulletin. Volume 7, Issue 3, June 2005

    Science.gov (United States)

    2005-06-01

    War Conflicts. (San Francisco: Jossey- Bass Publishers, 2001), 211. 2"Coalition Building,” op.cit 4 Joint Center for Operational Analysis and Lessons...Lessons Learned (CALL) 10 Meade Avenue Bldg. 50 Fort Leavenworth, KS 66027 user name phone# COL Larry Saul , Director (Lawrence.saul) x2255 Mr. Larry

  12. Cost-income analysis of oral health units of health care centers in Yazd city

    Directory of Open Access Journals (Sweden)

    Hosein Fallahzadeh

    2012-01-01

    Full Text Available Background and Aims: Increasing demands for health care's services on one hand and limited resources on the other hand brings about pressure over governments to find out a mechanism for fair and appropriate distribution of resources. Economic analysis is one of the appropriate tools for policy making on this priority. The aim of this study was to assess capital and consumption of oral health units of health care centers in Yazd city and comparing it with revenue of these centers and determining of cost effectiveness.Materials and Methods: In this descriptive cross sectional study, all health care centers of Yazd city with active dentistry department were evaluated. The data has been extracted from current documents in health care center of county based issued receipts and daily information registers.Results: Expended cost for providing of oral hygiene services in second half of 2008 in 13 medical health centers of Yazd included active dentistry section was 557.887.500 Rials and revenue to cost ratio was about 34%. The most provided service was related to tooth extraction and the average of tooth restoration in each working day was 0.48.Conclusion: With attention to low tariffs of dentistry services in medical health centers and paying subsidy to target groups, expenses of oral hygiene are always more than its revenue.

  13. Capability of the Gas Analysis and Testing Laboratory at the NASA Johnson Space Center

    Science.gov (United States)

    Broerman, Craig; Jimenez, Javier; Sweterlitsch, Jeff

    2012-01-01

    The Gas Analysis and Testing Laboratory is an integral part of the testing performed at the NASA Johnson Space Center. The Gas Analysis and Testing Laboratory is a high performance laboratory providing real time analytical instruments to support manned and unmanned testing. The lab utilizes precision gas chromatographs, gas analyzers and spectrophotometers to support the technology development programs within the NASA community. The Gas Analysis and Testing Laboratory works with a wide variety of customers and provides engineering support for user-specified applications in compressed gas, chemical analysis, general and research laboratory.

  14. User and Task Analysis of the Flight Surgeon Console at the Mission Control Center of the NASA Johnson Space Center

    Science.gov (United States)

    Johnson, Kathy A.; Shek, Molly

    2003-01-01

    Astronauts in a space station are to some extent like patients in an intensive care unit (ICU). Medical support of a mission crew will require acquisition, transmission, distribution, integration, and archiving of significant amounts of data. These data are acquired by disparate systems and will require timely, reliable, and secure distribution to different communities for the execution of various tasks of space missions. The goal of the Comprehensive Medical Information System (CMIS) Project at Johnson Space Center Flight Medical Clinic is to integrate data from all Medical Operations sources, including the reference information sources and the electronic medical records of astronauts. A first step toward the full CMIS implementation is to integrate and organize the reference information sources and the electronic medical record with the Flight Surgeons console. In order to investigate this integration, we need to understand the usability problems of the Flight Surgeon's console in particular and medical information systems in general. One way to achieve this understanding is through the use of user and task analyses whose general purpose is to ensure that only the necessary and sufficient task features that match users capacities will be included in system implementations. The goal of this summer project was to conduct user and task analyses employing cognitive engineering techniques to analyze the task of the Flight Surgeons and Biomedical Engineers (BMEs) while they worked on Console. The techniques employed were user interviews, observations and a questionnaire to collect data for which a hierarchical task analysis and an information resource assessment were performed. They are described in more detail below. Finally, based on our analyses, we make recommendations for improvements to the support structure.

  15. Fiscal Year 1998 Annual Report, Carbon Dioxide Information Analysis Center, World Data Center -- A for Atmospheric Trace Gases

    Energy Technology Data Exchange (ETDEWEB)

    Cushman, R.M.; Boden, T.A.; Hook, L.A.; Jones, S.B.; Kaiser, D.P.; Nelson, T.R.

    1999-03-01

    Once again, the most recent fiscal year was a productive one for the Carbon Dioxide Information Analysis Center (CDIAC) at Oak Ridge National Laboratory (ORNL), as well as a year for change. The FY 1998 in Review section in this report summarizes quite a few new and updated data and information products, and the ''What's Coming in FY 1999'' section describes our plans for this new fiscal year. During FY 1998, CDIAC began a data-management system for AmeriFlux, a long-term study of carbon fluxes between the terrestrial biosphere of the Western Hemisphere and the atmosphere. The specific objectives of AmeriFlux are to establish an infrastructure for guiding, collecting, synthesizing, and disseminating long-term measurements of CO{sub 2}, water, and energy exchange from a variety of ecosystems; collect critical new information to help define the current global CO{sub 2} budget; enable improved predictions of future concentrations of atmospheric CO{sub 2}; and enhance understanding of carbon fluxes. Net Ecosystem Production (NEP), and carbon sequestration in the terrestrial biosphere. The data-management system, available from CDIAC'S AmeriFlux home page (http://cdiac.esd.ornl.gov/programs/ameriflux/ ) is intended to provide consistent, quality-assured, and documented data across all AmeriFlux sites in the US, Canada, Costa Rica, and Brazil. It is being developed by Antoinette Brenkert and Tom Boden, with assistance from Susan Holladay (who joined CDIAC specifically to support the AmeriFlux data-management effort).

  16. In Vivo Verification of Different Hip Joint Center Estimation Methods in Gait Analysis For Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Abdollah YOUSEFI

    2015-01-01

    Full Text Available Hip joint is one of the most stable joints in human body. It has intrinsic stability provided by its relatively rigid ball and socket configuration. The hip joint also has a wide range of motion, which allows normal locomotion and daily activities. Location of hip joint center (HJC is an important parameter in gait analysis, biomechanical and clinical research laboratories to calculate human lower extremity kinematics and kinetics. Inaccuracies in estimation of hip joint center are shown to propagate errors in kinematic and kinetic calculations of lower extremities

  17. Opareí: Transitional Justice in Paraguay Opareí. La justicia de transición en Paraguay

    Directory of Open Access Journals (Sweden)

    Maria ROSARIA STABILI

    2012-10-01

    Full Text Available The purpose of This paper is to analyze, after giving a synthetic reconstruction of The Stroessner’s regime, The complex dynamics of transitional justice in Paraguay. Special attention is devoted to The discovery in 1992 of The Archivos del Terror (The Horror Files and The establishment and operation of The Commission for Truth and justice That was created in October 2003 by President Nicanor Duarte Frutos. It also reflects about The reactions of politicians and The judiciary to The recommendations and remedial measures suggested by The final report of The Commission.El propósito del artículo es analizar, después de haber ofrecido una reconstrucción sintética del régimen de Stroessner, las complejas dinámicas de la justicia de transición en Paraguay. Especial atención se dedica al descubrimiento, en 1992, de los «Archivos del Terror» y a la constitución y funcionamiento de la Comisión de Verdad y justicia creada, en octubre 2003, por el presidente de la República, Nicanor Duarte Frutos. También se reflexiona sobre las reacciones de los políticos y del Poder Judicial a las recomendaciones y medidas de reparación sugeridas del informe final de dicha Comisión.

  18. Analysis of bearings behaviour with cylindrical rollers with variable center of gravity

    Directory of Open Access Journals (Sweden)

    Barabas Sorin

    2017-01-01

    Full Text Available This paper consists in analysis of the contact stress and deformations appeared to the cylindrical rollers with variable center of gravity who equips large bearings, with finite elements method. Also it proposed an innovative model of lubrication system mounts in the hollow cylindrical rollers of the large bearings where it is stored the lubricant who is driven to the raceways through holes fitted with closing/opening systems made in the cover, controlled by a command system, monitoring and control, equipped with temperature sensors and wireless command. Elimination of lubricant, in stages, leads to changes in position of center of gravity of roller, thus to change its behavior in functioning. Comparison of deformations occurred in cylindrical rollers, solid, with hollowness, and with variable center of gravity, allow favorable conclusions, on the implementation of the proposed lubrication system.

  19. Radiological environmental pathway screening analysis for the Feed Materials Production Center (FMPC)

    Energy Technology Data Exchange (ETDEWEB)

    Eckart, R.; Carr, D.; Conner, B.; Janke, R.; Janke, R.

    1989-11-01

    The University of Cincinnati is working with the Westinghouse Materials Company of Ohio (WMCO) to develop remedial action residual radioactive material soil guidelines for the Feed Materials Production Center (FMPC). As a first step in developing these soil guidelines, a radiological environmental pathway screening analysis was performed. The purpose of the pathway screening analysis was to identify the radionuclides and environmental pathways that would lead to the highest exposure or dose to humans from residual radioactivity in the soil at the FMPC. In addition, the screening analysis identifies those pathways that are critical to a particular radioisotope.

  20. A Cost–Benefit Analysis to Assess the Effectiveness of Frontal Center Curtain Airbag

    Directory of Open Access Journals (Sweden)

    Bo Kyeong Lee

    2017-09-01

    Full Text Available Several new varieties of airbags are under consideration for development. However, their commercialization decision must be backed by a positive Cost–Benefit Analysis (CBA outcome. In this study, we propose a CBA framework for the frontal center curtain airbag, a newly designed safety system intended to reduce the injury risk of rear-seat passengers. The proposed CBA covers not only economic benefits of the producer but also the effectiveness in sustainable reduction of the fatal and injury rate. In this context, with accumulated field data on road traffic accidents, a forecasting method reflecting the reduced casualties and the market share of vehicle sales associated with frontal center curtain airbag is utilized. Our results suggest that the use of frontal center curtain airbags helps to reduce the number of casualties with a Maximum Abbreviated Injury Scale (MAIS of 3 or above by 87.4%. Furthermore, both the initial market penetration rate and price of the frontal center curtain airbag significantly influence its socioeconomic benefits. By evaluating the effectiveness of the frontal center curtain airbag, our study can contribute to the decision making for its commercialization.

  1. Numerical analysis of thermal environment control in high density data center

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Oh Kyung; Kim, Hyeon Joong; Cha, Dong An [Korea Institute of Industrial Technology, Cheonan (Korea, Republic of)

    2012-08-15

    Increasing heat generation in CPUs can hamper effective recirculation and by pass because of the large temperature difference between the exhaust and the intake air through a server room. This increases the overall temperature inside a data center and decreases the efficiency of the data center's cooling system. The purpose of the data center's cooling system is to separate the intake and exhaust air by controlling the computer room air conditioner(CRAC). In this study, ICEPAK is used to conduct a numerical analysis of a data center's cooling system. The temperature distribution and the entire room are analyzed for different volumetric flow rates. The optimized volumetric flow rate is found for each CPU power. The heat removal and temperature distribution for CPU powers of 100, 120, and 140W are found to be the best for a volumetric flow rate of 0.15m'3'/s. The numerical analysis is verified through RTI indicators, and the results appear to be the most reliable when the RTI value is 81.

  2. Finite-element analysis of the center of resistance of the mandibular dentition

    Science.gov (United States)

    Jo, A-Ra; Lee, Kee-Joon; Sung, Sang-Jin; Chun, Youn-Sic

    2017-01-01

    Objective The aim of this study was to investigate the three-dimensional (3D) position of the center of resistance of 4 mandibular anterior teeth, 6 mandibular anterior teeth, and the complete mandibular dentition by using 3D finite-element analysis. Methods Finite-element models included the complete mandibular dentition, periodontal ligament, and alveolar bone. The crowns of teeth in each group were fixed with buccal and lingual arch wires and lingual splint wires to minimize individual tooth movement and to evenly disperse the forces onto the teeth. Each group of teeth was subdivided into 0.5-mm intervals horizontally and vertically, and a force of 200 g was applied on each group. The center of resistance was defined as the point where the applied force induced parallel movement. Results The center of resistance of the 4 mandibular anterior teeth group was 13.0 mm apical and 6.0 mm posterior, that of the 6 mandibular anterior teeth group was 13.5 mm apical and 8.5 mm posterior, and that of the complete mandibular dentition group was 13.5 mm apical and 25.0 mm posterior to the incisal edge of the mandibular central incisors. Conclusions Finite-element analysis was useful in determining the 3D position of the center of resistance of the 4 mandibular anterior teeth group, 6 mandibular anterior teeth group, and complete mandibular dentition group. PMID:28127536

  3. THE ANALYSIS OF THE DIABETIC FOOT OSTEOMYELITIS AT A TERTIARY CARE CENTER - A PROSPECTIVE STUDY

    OpenAIRE

    Mithun N; Pattanashetty; Reshmina; Sharath Babu; Harikrishna; Sreedhar Reddy; Ramakrishna J

    2015-01-01

    INTRODUCTION : India is considered as the diabetic capital of the world. Diabetic foot osteomyelitis is considered as one of the severe complications of diabetes mellitus. Diabetic foot osteomyelitis tends to complicate around one third of diabetic foot infections. In v iew of this we conducted a prospective study on the bacteriological analysis of diabetic foot osteomyelitis at a tertiary care center. MATERIALS AND METHODS : A prospective study was perform...

  4. Comparison of patient outcomes in academic medical centers with and without value analysis programs

    Directory of Open Access Journals (Sweden)

    Murray AS

    2012-09-01

    Full Text Available Adrienne S Murray, Michael Griswold, Imran Sunesara, Ed SmithUniversity of Mississippi Health Care, University of Mississippi Medical Center, Jackson, MS, USABackground: Value analysis is the science of balancing the mandate to deliver high-quality clinical outcomes with the necessity to drive down costs in order to thrive in the challenging economics of health care. This study compared average length of stay, direct cost, morbidity, and mortality across the cardiology, cardiovascular, neuroscience, and orthopedic service lines, in academic medical centers with and without value analysis programs (VAPs. The basic question was, “Do academic medical centers with VAPs have lower average length of stay, better morbidity and mortality rates, and lower overall supply costs?”Methods and results: The clinical data base/resource manager (CDB/RM of the University HealthSystem Consortium was utilized as secondary data for this study. Reports from the CDB/RM were generated from 2006 to 2011. Continuous variable differences across VAP status were examined using Wilcoxon two-sample tests. Primary analyses used multilevel linear mixed model methods to estimate the effects of VAPs on primary outcomes (average length of stay, cost, morbidity, mortality. Association components of the linear mixed models incorporated random effects at the hospital level and robust, Huber-White, standard errors were calculated. There was no significant difference for average length of stay, direct cost, morbidity, and mortality between academic medical centers with and without VAPs. However, outcomes were not noted to be substantially worse.Conclusion: Numerous case studies reveal that aggressively active VAPs do decrease hospital cost. Also, this study did not find a negative impact on patient care. Further studies are needed to explore the benefits of value analysis and its effect on patient outcomes.Keywords: value analysis, average length of stay, morbidity, mortality

  5. Reliability Information Analysis Center 1st Quarter 2007, Technical Area Task (TAT) Report

    Science.gov (United States)

    2007-02-05

    07 planning conference 14 Dec 06 II Marine Expeditionary Force (MEF) meeting with Major Smith 14 Dec 06 Gulf of Mexico Tyndall Air Force Base Missile...Restructured action item spreadsheet " Reviewed the following storyboards (functional flow, graphics and text): 1. 050101 Main Rotor System components 2... storyboards (functional flow, graphics, and text): o 050101 Main Rotor System components. Reliability Information Analysis Center 6000 Flanagan Road

  6. Outpatient imaging center valuations: do you need a fair-market value analysis?

    Science.gov (United States)

    Koonsman, G S

    2001-01-01

    Typically, outpatient diagnostic imaging centers are formed as partnerships between radiologists, radiologists and hospitals, and/or radiologists and diagnostic imaging center management companies. As a result of these partnership structures, the question of equity valuation frequently arises. It is not only important to understand when an independent valuation would be required, but also what "type" of valuation needs to be performed. The type of valuation may vary based upon the use of the valuation. In partnerships that involve hospitals and physicians, the federal anti-kickback statutes (fraud and abuse laws) require that all transactions between referring physicians and hospitals be consummated at fair-market value. In addition, tax-exempt hospitals that enter into partnerships with physicians are required to enter into those transactions at fair-market value or risk losing their tax-exempt status. Fair-market value is also typically the standard of value that all partnerships strive to conduct equity transactions with shareholders. Qualifications required by those who perform independent fair-market value opinions include: Proper business valuation training and focus on valuations as a primary business Focus on the healthcare industry and specifically on the valuation of diagnostic imaging centers In order to perform a reasonable business valuation analysis, the appraiser must have access to a significant amount of financial, operational and legal information. The analyst must be able to understand the history of the imaging center as well as the projected future of the center. Ultimately, a valuation is a measurement of the estimated future cash flows of the center--risk adjusted--in order to quantify the present value of those cash flows.

  7. Finite Element Analysis and Test Results Comparison for the Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.

    2016-01-01

    This report documents the comparison of test measurements and predictive finite element analysis results for a hybrid wing body center section test article. The testing and analysis efforts were part of the Airframe Technology subproject within the NASA Environmentally Responsible Aviation project. Test results include full field displacement measurements obtained from digital image correlation systems and discrete strain measurements obtained using both unidirectional and rosette resistive gauges. Most significant results are presented for the critical five load cases exercised during the test. Final test to failure after inflicting severe damage to the test article is also documented. Overall, good comparison between predicted and actual behavior of the test article is found.

  8. Analysis of the structural consensus of the zinc coordination centers of metalloprotein structures.

    Science.gov (United States)

    Patel, Kirti; Kumar, Anil; Durani, Susheel

    2007-10-01

    In a recent sequence-analysis study it was concluded that up to 10% of the human proteome could be comprised of zinc proteins, quite varied in the functional spread. The native structures of only few of the proteins are actually established. The elucidation of rest of the sequences of not just human but even other actively investigated genomes may benefit from knowledge of the structural consensus of the zinc-binding centers of the currently known zinc proteins. Nearly four hundred X-ray and NMR structures in the database of zinc-protein structures available as of April 2007 were investigated for geometry and conformation in the zinc-binding centers; separately for the structural and catalytic proteins and individually in the zinc centers coordinated to three and four amino-acid ligands. Enhanced cysteine involvement in agreement with the observation in human proteome has been detected in contrast with previous reports. Deviations from ideal coordination geometries are detected, possible underlying reasons are investigated, and correlations of geometry and conformation in zinc-coordination centers with protein function are established, providing possible benchmarks for putative zinc-binding patterns of the burgeoning genome data.

  9. Acid-base analysis: a critique of the Stewart and bicarbonate-centered approaches.

    Science.gov (United States)

    Kurtz, Ira; Kraut, Jeffrey; Ornekian, Vahram; Nguyen, Minhtri K

    2008-05-01

    When approaching the analysis of disorders of acid-base balance, physical chemists, physiologists, and clinicians, tend to focus on different aspects of the relevant phenomenology. The physical chemist focuses on a quantitative understanding of proton hydration and aqueous proton transfer reactions that alter the acidity of a given solution. The physiologist focuses on molecular, cellular, and whole organ transport processes that modulate the acidity of a given body fluid compartment. The clinician emphasizes the diagnosis, clinical causes, and most appropriate treatment of acid-base disturbances. Historically, two different conceptual frameworks have evolved among clinicians and physiologists for interpreting acid-base phenomena. The traditional or bicarbonate-centered framework relies quantitatively on the Henderson-Hasselbalch equation, whereas the Stewart or strong ion approach utilizes either the original Stewart equation or its simplified version derived by Constable. In this review, the concepts underlying the bicarbonate-centered and Stewart formulations are analyzed in detail, emphasizing the differences in how each approach characterizes acid-base phenomenology at the molecular level, tissue level, and in the clinical realm. A quantitative comparison of the equations that are currently used in the literature to calculate H(+) concentration ([H(+)]) is included to clear up some of the misconceptions that currently exist in this area. Our analysis demonstrates that while the principle of electroneutrality plays a central role in the strong ion formulation, electroneutrality mechanistically does not dictate a specific [H(+)], and the strong ion and bicarbonate-centered approaches are quantitatively identical even in the presence of nonbicarbonate buffers. Finally, our analysis indicates that the bicarbonate-centered approach utilizing the Henderson-Hasselbalch equation is a mechanistic formulation that reflects the underlying acid-base phenomenology.

  10. Johnson Space Center's Risk and Reliability Analysis Group 2008 Annual Report

    Science.gov (United States)

    Valentine, Mark; Boyer, Roger; Cross, Bob; Hamlin, Teri; Roelant, Henk; Stewart, Mike; Bigler, Mark; Winter, Scott; Reistle, Bruce; Heydorn,Dick

    2009-01-01

    The Johnson Space Center (JSC) Safety & Mission Assurance (S&MA) Directorate s Risk and Reliability Analysis Group provides both mathematical and engineering analysis expertise in the areas of Probabilistic Risk Assessment (PRA), Reliability and Maintainability (R&M) analysis, and data collection and analysis. The fundamental goal of this group is to provide National Aeronautics and Space Administration (NASA) decisionmakers with the necessary information to make informed decisions when evaluating personnel, flight hardware, and public safety concerns associated with current operating systems as well as with any future systems. The Analysis Group includes a staff of statistical and reliability experts with valuable backgrounds in the statistical, reliability, and engineering fields. This group includes JSC S&MA Analysis Branch personnel as well as S&MA support services contractors, such as Science Applications International Corporation (SAIC) and SoHaR. The Analysis Group s experience base includes nuclear power (both commercial and navy), manufacturing, Department of Defense, chemical, and shipping industries, as well as significant aerospace experience specifically in the Shuttle, International Space Station (ISS), and Constellation Programs. The Analysis Group partners with project and program offices, other NASA centers, NASA contractors, and universities to provide additional resources or information to the group when performing various analysis tasks. The JSC S&MA Analysis Group is recognized as a leader in risk and reliability analysis within the NASA community. Therefore, the Analysis Group is in high demand to help the Space Shuttle Program (SSP) continue to fly safely, assist in designing the next generation spacecraft for the Constellation Program (CxP), and promote advanced analytical techniques. The Analysis Section s tasks include teaching classes and instituting personnel qualification processes to enhance the professional abilities of our analysts

  11. Mean centering of double divisor ratio spectra, a novel spectrophotometric method for analysis of ternary mixtures

    Science.gov (United States)

    Hassan, Said A.; Elzanfaly, Eman S.; Salem, Maissa Y.; El-Zeany, Badr A.

    2016-01-01

    A novel spectrophotometric method was developed for determination of ternary mixtures without previous separation, showing significant advantages over conventional methods. The new method is based on mean centering of double divisor ratio spectra. The mathematical explanation of the procedure is illustrated. The method was evaluated by determination of model ternary mixture and by the determination of Amlodipine (AML), Aliskiren (ALI) and Hydrochlorothiazide (HCT) in laboratory prepared mixtures and in a commercial pharmaceutical preparation. For proper presentation of the advantages and applicability of the new method, a comparative study was established between the new mean centering of double divisor ratio spectra (MCDD) and two similar methods used for analysis of ternary mixtures, namely mean centering (MC) and double divisor of ratio spectra-derivative spectrophotometry (DDRS-DS). The method was also compared with a reported one for analysis of the pharmaceutical preparation. The method was validated according to the ICH guidelines and accuracy, precision, repeatability and robustness were found to be within the acceptable limits.

  12. Family-Centered Care in Neonatal Intensive Care Unit: A Concept Analysis

    Science.gov (United States)

    Ramezani, Tahereh; Hadian Shirazi, Zahra; Sabet Sarvestani, Raheleh; Moattari, Marzieh

    2014-01-01

    Background: The concept of family- centered care in neonatal intensive care unit has changed drastically in protracted years and has been used in various contexts differently. Since we require clarity in our understanding, we aimed to analyze this concept. Methods: This study was done on the basis of developmental approach of Rodgers’s concept analysis. We reviewed the existing literature in Science direct, PubMed, Google Scholar, Scopus, and Iran Medex databases from 1980 to 2012. The keywords were family-centered care, family-oriented care, and neonatal intensive care unit. After all, 59 out of 244 English and Persian articles and books (more than 20%) were selected. Results: The attributes of family-centered care in neonatal intensive care unit were recognized as care taking of family (assessment of family and its needs, providing family needs), equal family participation (participation in care planning, decision making, and providing care from routine to special ones), collaboration (inter-professional collaboration with family, family involvement in regulating and implementing care plans), regarding family’s respect and dignity (importance of families’ differences, recognizing families’ tendencies), and knowledge transformation (information sharing between healthcare workers and family, complete information sharing according to family learning style). Besides, the recognized antecedents were professional and management-organizational factors. Finally, the consequences included benefits related to neonate, family, and organization. Conclusion: The findings revealed that family centered-care was a comprehensive and holistic caring approach in neonatal intensive care. Therefore, it is highly recommended to change the current care approach and philosophy and provide facilities for conducting family-centered care in neonatal intensive care unit.  PMID:25349870

  13. Pooling fMRI data: meta-analysis, mega-analysis and multi-center studies

    Directory of Open Access Journals (Sweden)

    Sergi G Costafreda

    2009-09-01

    Full Text Available The quantitative analysis of pooled data from related fMRI experiments has the potential to significantly accelerate progress in brain mapping. Such data-pooling can be achieved through meta-analysis (the pooled analysis of published results, mega-analysis (the pooled analysis of raw data or multi-site studies which can be seen as designed mega-analyses. Current limitations in function-location brain mapping and how data-pooling can be used to remediate them are reviewed, with particular attention to power aggregation and mitigation of false positive results. Some recently developed analysis tools for meta- and mega-analysis are also presented, and recommendations for the conduct of valid fMRI data pooling are formulated.

  14. AN ANALYSIS ON THE DETERMINANTS OF SERVICE QUALITY PERCEIVED BY MEMBERS OF THE FITNESS CENTER

    Directory of Open Access Journals (Sweden)

    Kadir YILDIZ

    2016-12-01

    Full Text Available In this research, it is aimed to determine the determinants of service quality perceived by fitness center members. Scanning model from quantitative research methods was used in the research. The study group consisted of 301 women and 390 men in total 691 members who participated the research voluntarily and were selected through an easily accessible sample. The "Sport-Fitness Centers Perceived Service Quality Scale (SFC-PSQS" developed by Uçan (2007 was used in the study. In the analysis of the data, independent t-test, correlation analysis and logistic regression tests were applied. According to obtained findings, significant and moderate relationships were determined between service quality sub-dimensions in positive direction whereas Independent T test results showed that service quality perceptions of participants who evaluated the program as expensive were found to be significantly lower in all sub-dimensions. Considering the logistic regression results, it was determined that variable of "physical environment quality" from perceived service quality sub-dimensions had an effect on the level of program fees of the members. It seems that 1 unit increase in physical environment quality variable caused 6.1% decrease in "program fee prediction" related to odds value. It can be stated that 11% of the total variance of program fee levels predicts perceived service quality. As a result, it is considered that only one factor cannot be effective in ensuring the continuity of sport-fitness center customers and the sustainability of the business. This is because factors such as customer expectations, equipment, experience of fitness center, customer loyalty, physical appearance that may affect individual consumer satisfaction are important factors.

  15. Nonlinear Analysis and Preliminary Testing Results of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.; Wu, Hsi-Yung T.

    2015-01-01

    A large test article was recently designed, analyzed, fabricated, and successfully tested up to the representative design ultimate loads to demonstrate that stiffened composite panels with through-the-thickness reinforcement are a viable option for the next generation large transport category aircraft, including non-conventional configurations such as the hybrid wing body. This paper focuses on finite element analysis and test data correlation of the hybrid wing body center section test article under mechanical, pressure and combined load conditions. Good agreement between predictive nonlinear finite element analysis and test data is found. Results indicate that a geometrically nonlinear analysis is needed to accurately capture the behavior of the non-circular pressurized and highly-stressed structure when the design approach permits local buckling.

  16. Investigating Student Communities with Network Analysis of Interactions in a Physics Learning Center

    CERN Document Server

    Brewe, Eric; Sawtelle, Vashti

    2011-01-01

    Developing a sense of community among students is one of the three pillars of an overall reform effort to increase participation in physics, and the sciences more broadly, at Florida International University. The emergence of a research and learning community, embedded within a course reform effort, has contributed to increased recruitment and retention of physics majors. Finn and Rock [1] link the academic and social integration of students to increased rates of retention. We utilize social network analysis to quantify interactions in Florida International University's Physics Learning Center (PLC) that support the development of academic and social integration,. The tools of social network analysis allow us to visualize and quantify student interactions, and characterize the roles of students within a social network. After providing a brief introduction to social network analysis, we use sequential multiple regression modeling to evaluate factors which contribute to participation in the learning community. ...

  17. Dipole Analysis of 249 High-Z SCP Union Supernovae According to the Expansion Center Model

    CERN Document Server

    Lorenzi, Luciano

    2011-01-01

    The topic of the paper is a preliminary analysis of 1743 data calculated for 249 High-z SCP Union supernovae, according to the expansion center model. The analysis of the ECM data set in Hubble units begins with 13 listed normal points corresponding to 13 z-bin samples at as many Hubble depths. Here the novel finding is a resulting clear drop in the average scattering of the SNe Ia absolute magnitudes M with the ECM Hubble depth D, after using the average trend computed in paper IX and here reconfirmed. Other correlations of the M scattering with the position in the sky are proposed as pointers for future investigations. Consequently, 13 ECM dipole tests on the 13 z-bin samples were carried out both with unweighed and weighed fittings. A further check was made through another ECM dipole test on the same 13 z bins, with Hubble depths D obtained by assuming M= according to paper IX and X. In conclusion the analysis of 249 SCP SNe confirms once again the expansion center model at any Hubble depth, including a s...

  18. Clinical process analysis and activity-based costing at a heart center.

    Science.gov (United States)

    Ridderstolpe, Lisa; Johansson, Andreas; Skau, Tommy; Rutberg, Hans; Ahlfeldt, Hans

    2002-08-01

    Cost studies, productivity, efficiency, and quality of care measures, the links between resources and patient outcomes, are fundamental issues for hospital management today. This paper describes the implementation of a model for process analysis and activity-based costing (ABC)/management at a Heart Center in Sweden as a tool for administrative cost information, strategic decision-making, quality improvement, and cost reduction. A commercial software package (QPR) containing two interrelated parts, "ProcessGuide and CostControl," was used. All processes at the Heart Center were mapped and graphically outlined. Processes and activities such as health care procedures, research, and education were identified together with their causal relationship to costs and products/services. The construction of the ABC model in CostControl was time-consuming. However, after the ABC/management system was created, it opened the way for new possibilities including process and activity analysis, simulation, and price calculations. Cost analysis showed large variations in the cost obtained for individual patients undergoing coronary artery bypass grafting (CABG) surgery. We conclude that a process-based costing system is applicable and has the potential to be useful in hospital management.

  19. A Discourse Analysis of the Centered and Critical Scholar-Activism of Martin Luther King Jr.

    OpenAIRE

    Keatts, Quenton

    2010-01-01

    The purpose of this project is to investigate the often neglected research concerning the Reverend Dr. Martin Luther King, Jr. and his scholar-activism. This project is intended to look for evidence of intellectual leadership within Kingâ s writings in an effort to classify King within the Scholar-Activist paradigm in Africana Studies. Further, the aim is to examine Martin Luther King, Jr. from the critical and centered Scholar-Activist paradigm of Africana Studies based on an analysis of ...

  20. TIME ANALYSIS ACCORDING TO PART PROGRAMS ON A CNC VERTICAL MACHINING CENTER

    Directory of Open Access Journals (Sweden)

    Ahmet Murat PİNAR

    2002-01-01

    Full Text Available In this study, a program examining the CNC programs in the control unit of Dyna Myte 2900 Vertical Machining Center and calculating the machining time and rapid movement time of the cutting tools has been developed. The workpiece program to be examined is transferred to CNC code editor by the user manually, by a computer file with a diskette, or through hard disk or the machine tool. By examining all the movements of the cutting tools, detailed machining time, rapid movement time or total time is served to the user. So that, an important part of workpiece cost analysis information is provided.

  1. NASA-Langley Research Center's Aircraft Condition Analysis and Management System Implementation

    Science.gov (United States)

    Frye, Mark W.; Bailey, Roger M.; Jessup, Artie D.

    2004-01-01

    This document describes the hardware implementation design and architecture of Aeronautical Radio Incorporated (ARINC)'s Aircraft Condition Analysis and Management System (ACAMS), which was developed at NASA-Langley Research Center (LaRC) for use in its Airborne Research Integrated Experiments System (ARIES) Laboratory. This activity is part of NASA's Aviation Safety Program (AvSP), the Single Aircraft Accident Prevention (SAAP) project to develop safety-enabling technologies for aircraft and airborne systems. The fundamental intent of these technologies is to allow timely intervention or remediation to improve unsafe conditions before they become life threatening.

  2. Digital image analysis of ossification centers in the axial dens and body in the human fetus.

    Science.gov (United States)

    Baumgart, Mariusz; Wiśniewski, Marcin; Grzonkowska, Magdalena; Małkowski, Bogdan; Badura, Mateusz; Dąbrowska, Maria; Szpinda, Michał

    2016-12-01

    The detailed understanding of the anatomy and timing of ossification centers is indispensable in both determining the fetal stage and maturity and for detecting congenital disorders. This study was performed to quantitatively examine the odontoid and body ossification centers in the axis with respect to their linear, planar and volumetric parameters. Using the methods of CT, digital image analysis and statistics, the size of the odontoid and body ossification centers in the axis in 55 spontaneously aborted human fetuses aged 17-30 weeks was studied. With no sex difference, the best fit growth dynamics for odontoid and body ossification centers of the axis were, respectively, as follows: for transverse diameter y = -10.752 + 4.276 × ln(age) ± 0.335 and y = -10.578 + 4.265 × ln(age) ± 0.338, for sagittal diameter y = -4.329 + 2.010 × ln(age) ± 0.182 and y = -3.934 + 1.930 × ln(age) ± 0.182, for cross-sectional area y = -7.102 + 0.520 × age ± 0.724 and y = -7.002 + 0.521 × age ± 0.726, and for volume y = -37.021 + 14.014 × ln(age) ± 1.091 and y = -37.425 + 14.197 × ln(age) ± 1.109. With no sex differences, the odontoid and body ossification centers of the axis grow logarithmically in transverse and sagittal diameters, and in volume, while proportionately in cross-sectional area. Our specific-age reference data for the odontoid and body ossification centers of the axis may be relevant for determining the fetal stage and maturity and for in utero three-dimensional sonographic detecting segmentation anomalies of the axis.

  3. DORIS data processing in the INASAN Analysis Center and the contribution to ITRF2014

    Science.gov (United States)

    Kuzin, Sergey; Tatevian, Suriya

    2016-12-01

    We present results of the DORIS data processing for the ITRF2014 carried out in the Institute of Astronomy, Russian Academy of Sciences (short INA) for the time period 1993.0-2015.0. The evaluated SINEX free-network (inawd08) weekly solutions for station positions and polar motion have been submitted to the IDS Combination Center. We applied the upgraded models of the gravity field, troposphere, and used corrected data for SPOT-5 satellite which permitted us to improve the result precision for Helmert transformation parameters and EOP. The agreement with the IERS C04 solution turns out better than 0.1 mas with a dispersion of 1 mas. The evaluated amplitudes of annual geocenter variations derived from inawd08 weekly solutions are 3.4 ± 0.5 mm, 4.4 ± 0.5 mm, and 3.3 ± 1.0 mm for X, Y, and Z components, respectively. The recovered amplitudes and phases are in a good agreement with the geophysical models. The results of two single satellite campaigns related to the scale increase in 2012 and 1994 for IDS combination are studied. Unlike other Analysis Centers, we did not apply a phase center law for ground antennas. It was shown that the correction for the phase center variation (PCV) of ground DORIS antennas results in the shift of the mean scale factor by 1.24 ppb (i.e., ∼8 mm) with respect to the case without correction. The PCV model and the satellites HY-2A and SARAL are included into the INA latest solutions (inawd10) after the submission for the ITRF2014. The future work is discussed.

  4. CAPITAL STRUCTURE ANALYSIS OF THE MEDICAL DIAGNOSTIC-CONSULTATIVE CENTERS IN VARNA (absolute indicators

    Directory of Open Access Journals (Sweden)

    Lyubomira Koeva-Dimitrova

    2016-08-01

    Full Text Available The capital structure analysis of medical institutions is related to the assessment of their financial sustainability. The degree of their financial sustainability indicates the extent to which the medical institution is exposed to financial risk. This financial risk is related to the use of foreign capital (debts, loans, etc. and it is defined as the probability of insolvency and possible bankruptcy due to the existence of debts which could not be repaid at some point in the foreseeable future. Objective: To analyze the capital structure of the medical diagnostic-consultative centers in Varna city and on this basis to assess their long-term solvency and existence of financial risk. Materials and Methods: The materials for the study are the published annual financial statements (up to 05. 01. 2016 in the Commercial Register for the period from year 2008 to 2014 of all MDCCs (Medical Diagnostic Consultative centers, registered in Varna - 9 in total. In the study are applied logical-mathematical methods (comparison, grouping, detail, graphical method; financial and accounting analysis (balance sheet analysis; analysis of absolute ratios for financial sustainability. Results: Upon analysis of the capital structure of MDCC's are studied the main absolute indicators characterizing the conditions for financial sustainability and the existence of financial risk regarding the solvency. A table represents the overall assessment of the degree of financial sustainability of the companies according to the type and structure of the fulfilled criteria. It was ascertained that for year 2014, DCC 3, 4, 5 and 8 have met all the conditions and according to them these hospitals have very high financial sustainability. DCC 7 has an average financial sustainability, DCC 1 and 2 are in a financial crisis and DCC 6 and 9 are facing bankruptcy. It must be emphasized that nearly half of the studied health care organizations (DCC 1, 2, 6 and 9 need urgent intervention by

  5. Structural analysis of the homodimeric reaction center complex from the photosynthetic green sulfur bacterium Chlorobaculum tepidum.

    Science.gov (United States)

    He, Guannan; Zhang, Hao; King, Jeremy D; Blankenship, Robert E

    2014-08-05

    The reaction center (RC) complex of the green sulfur bacterium Chlorobaculum tepidum is composed of the Fenna-Matthews-Olson antenna protein (FMO) and the reaction center core (RCC) complex. The RCC complex has four subunits: PscA, PscB, PscC, and PscD. We studied the FMO/RCC complex by chemically cross-linking the purified sample followed by biochemical and spectroscopic analysis. Blue-native gels showed that there were two types of FMO/RCC complexes, which are consistent with complexes with one copy of FMO per RCC and two copies of FMO per RCC. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of the samples after cross-linking showed that all five subunits of the RC can be linked by three different cross-linkers: bissulfosuccinimidyl suberate, disuccinimidyl suberate, and 3,3-dithiobis-sulfosuccinimidyl propionate. The interaction sites of the cross-linked complex were also studied using liquid chromatography coupled to tandem mass spectrometry. The results indicated that FMO, PscB, PscD, and part of PscA are exposed on the cytoplasmic side of the membrane. PscD helps stabilize FMO to the reaction center and may facilitate transfer of the electron from the RC to ferredoxin. The soluble domain of the heme-containing cytochrome subunit PscC and part of the core subunit PscA are located on the periplasmic side of the membrane. There is a close relationship between the periplasmic portions of PscA and PscC, which is needed for the efficient transfer of the electron between PscC and P840.

  6. Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center

    Science.gov (United States)

    Wattam, Alice R.; Davis, James J.; Assaf, Rida; Boisvert, Sébastien; Brettin, Thomas; Bun, Christopher; Conrad, Neal; Dietrich, Emily M.; Disz, Terry; Gabbard, Joseph L.; Gerdes, Svetlana; Henry, Christopher S.; Kenyon, Ronald W.; Machi, Dustin; Mao, Chunhong; Nordberg, Eric K.; Olsen, Gary J.; Murphy-Olson, Daniel E.; Olson, Robert; Overbeek, Ross; Parrello, Bruce; Pusch, Gordon D.; Shukla, Maulik; Vonstein, Veronika; Warren, Andrew; Xia, Fangfang; Yoo, Hyunseung; Stevens, Rick L.

    2017-01-01

    The Pathosystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center (https://www.patricbrc.org). Recent changes to PATRIC include a redesign of the web interface and some new services that provide users with a platform that takes them from raw reads to an integrated analysis experience. The redesigned interface allows researchers direct access to tools and data, and the emphasis has changed to user-created genome-groups, with detailed summaries and views of the data that researchers have selected. Perhaps the biggest change has been the enhanced capability for researchers to analyze their private data and compare it to the available public data. Researchers can assemble their raw sequence reads and annotate the contigs using RASTtk. PATRIC also provides services for RNA-Seq, variation, model reconstruction and differential expression analysis, all delivered through an updated private workspace. Private data can be compared by ‘virtual integration’ to any of PATRIC's public data. The number of genomes available for comparison in PATRIC has expanded to over 80 000, with a special emphasis on genomes with antimicrobial resistance data. PATRIC uses this data to improve both subsystem annotation and k-mer classification, and tags new genomes as having signatures that indicate susceptibility or resistance to specific antibiotics. PMID:27899627

  7. Analysis of the Service Quality of Medical Centers Using Servqual Model (Case:Shaheed Rahnemoon Hospital

    Directory of Open Access Journals (Sweden)

    H Zare Ahmadabadi

    2007-07-01

    Full Text Available Introduction: Many organizations, especially service oriented ones, relative to their goals and mission, have a special view towards quality phenomena and its management. Methods: This paper analyzes medical service quality in one case; The internal section of Shaheed Rahnemoon Hospital Based on the basis of gap analysis model and Servqual technique. A questionnaire was designed and applied to measure expectations and perceptions of patients and personnel of the hospital. Results: On application of non-parametric statistical tests, we propose certain recommendations. These tests drive on five conceptual dimensions of service quality including intangibility, responsiveness, reliability, assurance and empathy. Results show that patients in this section were satisfied from the service provider’s responsiveness, but there are significant differences between expectations and perceptions in other dimensions. Conclusion: The service quality analysis models are useful for managers of medical centers to distinguish gaps between the two sides of service representation; patients and medical centers personnel. Ultimately, they can reinforce strengths and control weaknesses.

  8. Development of Distributed Research Center for analysis of regional climatic and environmental changes

    Science.gov (United States)

    Gordov, E.; Shiklomanov, A.; Okladnikov, I.; Prusevich, A.; Titov, A.

    2016-11-01

    We present an approach and first results of a collaborative project being carried out by a joint team of researchers from the Institute of Monitoring of Climatic and Ecological Systems, Russia and Earth Systems Research Center UNH, USA. Its main objective is development of a hardware and software platform prototype of a Distributed Research Center (DRC) for monitoring and projecting of regional climatic and environmental changes in the Northern extratropical areas. The DRC should provide the specialists working in climate related sciences and decision-makers with accurate and detailed climatic characteristics for the selected area and reliable and affordable tools for their in-depth statistical analysis and studies of the effects of climate change. Within the framework of the project, new approaches to cloud processing and analysis of large geospatial datasets (big geospatial data) inherent to climate change studies are developed and deployed on technical platforms of both institutions. We discuss here the state of the art in this domain, describe web based information-computational systems developed by the partners, justify the methods chosen to reach the project goal, and briefly list the results obtained so far.

  9. Modeling and Analysis of Multidiscipline Research Teams at NASA Langley Research Center: A Systems Thinking Approach

    Science.gov (United States)

    Waszak, Martin R.; Barthelemy, Jean-Francois; Jones, Kenneth M.; Silcox, Richard J.; Silva, Walter A.; Nowaczyk, Ronald H.

    1998-01-01

    Multidisciplinary analysis and design is inherently a team activity due to the variety of required expertise and knowledge. As a team activity, multidisciplinary research cannot escape the issues that affect all teams. The level of technical diversity required to perform multidisciplinary analysis and design makes the teaming aspects even more important. A study was conducted at the NASA Langley Research Center to develop a model of multidiscipline teams that can be used to help understand their dynamics and identify key factors that influence their effectiveness. The study sought to apply the elements of systems thinking to better understand the factors, both generic and Langley-specific, that influence the effectiveness of multidiscipline teams. The model of multidiscipline research teams developed during this study has been valuable in identifying means to enhance team effectiveness, recognize and avoid problem behaviors, and provide guidance for forming and coordinating multidiscipline teams.

  10. NASA Marshall Space Flight Center Controls Systems Design and Analysis Branch

    Science.gov (United States)

    Gilligan, Eric

    2014-01-01

    Marshall Space Flight Center maintains a critical national capability in the analysis of launch vehicle flight dynamics and flight certification of GN&C algorithms. MSFC analysts are domain experts in the areas of flexible-body dynamics and control-structure interaction, thrust vector control, sloshing propellant dynamics, and advanced statistical methods. Marshall's modeling and simulation expertise has supported manned spaceflight for over 50 years. Marshall's unparalleled capability in launch vehicle guidance, navigation, and control technology stems from its rich heritage in developing, integrating, and testing launch vehicle GN&C systems dating to the early Mercury-Redstone and Saturn vehicles. The Marshall team is continuously developing novel methods for design, including advanced techniques for large-scale optimization and analysis.

  11. Caring for family caregivers: An analysis of a family-centered intervention

    Directory of Open Access Journals (Sweden)

    Carme Ferré-Grau

    2014-08-01

    Full Text Available Objective To assess the effectiveness of Problem-Solving Therapy (PST on family caregivers through the use of scales to measure anxiety, depression and emotional distress; and to explore facilitating factors and obstacles for its use based on the narrative of nurses. Method A clinical trial and an exploratory focus group with the use of mixed analysis methodology. The study was conducted in a primary health care center in Tarragona, Spain, and the sample consisted of 122 family caregivers who were included in the home care service, and 10 nurses who participated in the intervention group. Family caregivers with evident symptoms of anxiety, depression and emotional distress received PST in the intervention group. The intervention group also consisted of a discussion with eight nurses, which was transcribed and submitted to content analysis. Conclusion Problem-Solving Therapy proved to be effective in reducing perceived anxiety, depression and emotional distress. We identified its strong points and obstacles as described by nurses.

  12. Simulation Modeling and Analysis of the Impact of Individual Mobility Augmentee Loss at the Tanker Airlift Control Center

    Science.gov (United States)

    2012-06-01

    SIMULATION MODELING AND ANALYSIS OF THE IMPACT OF INDIVIDUAL MOBILITY AUGMENTEE LOSS AT THE TANKER...States Air Force, Department of Defense, or the United States Government. AFIT-OR-MS-ENS-12-18 SIMULATION MODELING AND ANALYSIS OF THE...58 1 SIMULATION MODELING AND ANALYSIS OF THE IMPACT OF INDIVIDUAL MOBILITY AUGMENTEE LOSS AT THE TANKER AIRLIFT CONTROL CENTER I

  13. Cost analysis of awake versus asleep deep brain stimulation: a single academic health center experience.

    Science.gov (United States)

    Jacob, R Lorie; Geddes, Jonah; McCartney, Shirley; Burchiel, Kim J

    2016-05-01

    less than the expected cost (ratio 0.97). CONCLUSIONS In this single academic medical center cost analysis, DBS performed asleep was associated with a lower cost variation relative to the awake procedure. Furthermore, costs compared favorably to UHC-affiliated hospitals. While asleep DBS is not yet standard practice, this center exclusively performs asleep DBS at a lower cost than comparable institutions.

  14. Person-centered methods configural frequency analysis (CFA) and other methods for the analysis of contingency tables

    CERN Document Server

    Stemmler, Mark

    2014-01-01

    This book takes an easy-to-understand look at the statistical approach called the person-centered method. Instead of analyzing means, variances and covariances of scale scores as in the common variable-centered approach, the person-centered approach analyzes persons or objects grouped according to their characteristic patterns or configurations in contingency tables. The main focus of the book will be on Configural Frequency Analysis (CFA; Lienert and Krauth, 1975) which is a statistical method that looks for over and under-frequented cells or patterns. Over frequented means that the observations in this cell or configuration are observed more often than expected, under-frequented means that this cell or configuration is observed less often than expected. In CFA a pattern or configuration that contains more observed cases than expected is called a type; similarly, a pattern or configuration that is less observed than expected are called an antitype. CFA is similar to log-linear modeling. In log-linear modelin...

  15. Hospital image and the positioning of service centers: an application in market analysis and strategy development.

    Science.gov (United States)

    Smith, S M; Clark, M

    1990-09-01

    The research confirms the coexistence of different images for hospitals, service centers within the same hospitals, and service programs offered by each of the service centers. The images of individual service centers are found not to be tied to the image of the host facility. Further, service centers and host facilities have differential rankings on the same service decision attributes. Managerial recommendations are offered for "image differentiation" between a hospital and its care centers.

  16. A Comprehensive Sensitivity Analysis of a Data Center Network with Server Virtualization for Business Continuity

    Directory of Open Access Journals (Sweden)

    Tuan Anh Nguyen

    2015-01-01

    Full Text Available Sensitivity assessment of availability for data center networks (DCNs is of paramount importance in design and management of cloud computing based businesses. Previous work has presented a performance modeling and analysis of a fat-tree based DCN using queuing theory. In this paper, we present a comprehensive availability modeling and sensitivity analysis of a DCell-based DCN with server virtualization for business continuity using stochastic reward nets (SRN. We use SRN in modeling to capture complex behaviors and dependencies of the system in detail. The models take into account (i two DCell configurations, respectively, composed of two and three physical hosts in a DCell0 unit, (ii failure modes and corresponding recovery behaviors of hosts, switches, and VMs, and VM live migration mechanism within and between DCell0s, and (iii dependencies between subsystems (e.g., between a host and VMs and between switches and VMs in the same DCell0. The constructed SRN models are analyzed in detail with regard to various metrics of interest to investigate system’s characteristics. A comprehensive sensitivity analysis of system availability is carried out in consideration of the major impacting parameters in order to observe the system’s complicated behaviors and find the bottlenecks of system availability. The analysis results show the availability improvement, capability of fault tolerance, and business continuity of the DCNs complying with DCell network topology. This study provides a basis of designing and management of DCNs for business continuity.

  17. Hospital-centered violence intervention programs: a cost-effectiveness analysis.

    Science.gov (United States)

    Chong, Vincent E; Smith, Randi; Garcia, Arturo; Lee, Wayne S; Ashley, Linnea; Marks, Anne; Liu, Terrence H; Victorino, Gregory P

    2015-04-01

    Hospital-centered violence intervention programs (HVIPs) reduce violent injury recidivism. However, dedicated cost analyses of such programs have not yet been published. We hypothesized that the HVIP at our urban trauma center is a cost-effective means for reducing violent injury recidivism. We conducted a cost-utility analysis using a state-transition (Markov) decision model, comparing participation in our HVIP with standard risk reduction for patients injured because of firearm violence. Model inputs were derived from our trauma registry and published literature. The 1-year recidivism rate for participants in our HVIP was 2.5%, compared with 4% for those receiving standard risk reduction resources. Total per-person costs of each violence prevention arm were similar: $3,574 for our HVIP and $3,515 for standard referrals. The incremental cost effectiveness ratio for our HVIP was $2,941. Our HVIP is a cost-effective means of preventing recurrent episodes of violent injury in patients hurt by firearms. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Analysis and Improvement of Upwind and Centered Schemes on Quadrilateral and Triangular Meshes

    Science.gov (United States)

    Huynh, H. T.

    2003-01-01

    Second-order accurate upwind and centered schemes are presented in a framework that facilitates their analysis and comparison. The upwind scheme employed consists of a reconstruction step (MUSCL approach) followed by an upwind step (Roe's flux-difference splitting). The two centered schemes are of Lax-Friedrichs (L-F) type. They are the nonstaggered versions of the Nessyahu-Tadmor (N-T) scheme and the CE/SE method with epilson = 1/2. The upwind scheme is extended to the case of two spatial dimensions (2D) in a straightforward manner. The N-T and CE/SE schemes are extended in a manner similar to the 2D extensions of the CE/SE scheme by Wang and Chang for a triangular mesh and by Zhang, Yu, and Chang for a quadrilateral mesh. The slope estimates, however, are simplified. Fourier stability and accuracy analyses are carried out for these schemes for the standard 1D and the 2D quadrilateral mesh cases. In the nonstandard case of a triangular mesh, the triangles must be paired up when analyzing the upwind and N-T schemes. An observation resulting in an extended N-T scheme which is faster and uses only one-third of the storage for flow data compared with the CE/SE method is presented. Numerical results are shown. Other improvements to the schemes are discussed.

  19. Strategy for Self-Centered Development from the Perspective of an Historical Analysis of Development

    Directory of Open Access Journals (Sweden)

    Alfredo Pérez Sánchez

    1998-04-01

    Full Text Available After acknowledging the three phases of historical analysis of development, and especially considering the research work done in the last twenty-five years by the Germans Dieter Sengcheus and Ulrich Mezel, the author presents the principle elements of a self-centered development strategy which highlights the following perspectives:dissociation, economic restructuring, and the new forms of an international division of labor among Third World economies.This document calls into question the underlying operation of the conventional theory of development and its current policy, which call for the increasing integration of the Third World in the world market as a means of going beyond development as it is commonly understood. Though being an integral element in the theory of self-centereddevelopment, temporary dissociation from the world market is proposed. The justification for the strategy of dissociation, excepting the recourse to some historical and paradigmatic reflections sketched by Friedrich List, has kept itself, of necessity, to the global and abstract level. This position is nothing, however, but a most direct analytical result deduced fromthe principle theoretical beginnings and the empirical observations of both the Theory of Dependence and Peripheral Capitalism. Although the review vents its criticism on (and mainly questions the practicality of the aforesaid conception, a more penetratingunderstanding of what the wager for such a strategy entails is found. Thus, the notion of self-centered development influences and gives impulse to a most extensive ideologicallymarked debate about the alternative conceptions of development.

  20. Pilot project for a commercial buildings Energy Analysis and Diagnostic Center (EADC) program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Capehart, B.L.

    1996-02-01

    Commercial energy use costs businesses around $70 billion annually. Many of these businesses are small and medium sized organizations that do not have the resources to help themselves, or to pay for professional engineering services to help reduce their energy costs and improve their economic competitiveness. Energy cost reduction actions with payback times of around two years could save the commercial sector 15--20%, or $10--$15 billion per year. This project was initially intended to evaluate the feasibility of performing commercial energy audits as an adjunct to the industrial audit program run by the US Department of Energy Industrial Office. This program is housed in 30 universities throughout the United States. Formerly known as Energy Analysis and Diagnostic Centers (EADC`s), the university programs are now called Industrial Assessment Centers (IAC`s) to reflect their expansion from energy use analyses to include waste and productivity analyses. The success of the EADC/IAC program in helping the manufacturing sector provides an excellent model for a similar program in the commercial buildings sector. This project has investigated using the EADC/IAC approach to performing energy audits for the commercial sector, and has determined that such an approach is feasible and cost effective.

  1. Distributed Research Center for Analysis of Regional Climatic Changes and Their Impacts on Environment

    Science.gov (United States)

    Shiklomanov, A. I.; Okladnikov, I.; Gordov, E. P.; Proussevitch, A. A.; Titov, A. G.

    2016-12-01

    Presented is a collaborative project carrying out by joint team of researchers from the Institute of Monitoring of Climatic and Ecological Systems, Russia and Earth Systems Research Center, University of New Hampshire, USA. Its main objective is development of a hardware and software prototype of Distributed Research Center (DRC) for monitoring and projecting of regional climatic and and their impacts on the environment over the Northern extratropical areas. In the framework of the project new approaches to "cloud" processing and analysis of large geospatial datasets (big geospatial data) are being developed. It will be deployed on technical platforms of both institutions and applied in research of climate change and its consequences. Datasets available at NCEI and IMCES include multidimensional arrays of climatic, environmental, demographic, and socio-economic characteristics. The project is aimed at solving several major research and engineering tasks: 1) structure analysis of huge heterogeneous climate and environmental geospatial datasets used in the project, their preprocessing and unification; 2) development of a new distributed storage and processing model based on a "shared nothing" paradigm; 3) development of a dedicated database of metadata describing geospatial datasets used in the project; 4) development of a dedicated geoportal and a high-end graphical frontend providing intuitive user interface, internet-accessible online tools for analysis of geospatial data and web services for interoperability with other geoprocessing software packages. DRC will operate as a single access point to distributed archives of spatial data and online tools for their processing. Flexible modular computational engine running verified data processing routines will provide solid results of geospatial data analysis. "Cloud" data analysis and visualization approach will guarantee access to the DRC online tools and data from all over the world. Additionally, exporting of data

  2. Overview of Engineering Design and Analysis at the NASA John C. Stennis Space Center

    Science.gov (United States)

    Ryan, Harry; Congiardo, Jared; Junell, Justin; Kirkpatrick, Richard

    2007-01-01

    A wide range of rocket propulsion test work occurs at the NASA John C. Stennis Space Center (SSC) including full-scale engine test activities at test facilities A-1, A-2, B-1 and B-2 as well as combustion device research and development activities at the E-Complex (E-1, E-2, E-3 and E-4) test facilities. The propulsion test engineer at NASA SSC faces many challenges associated with designing and operating a test facility due to the extreme operating conditions (e.g., cryogenic temperatures, high pressures) of the various system components and the uniqueness of many of the components and systems. The purpose of this paper is to briefly describe the NASA SSC Engineering Science Directorate s design and analysis processes, experience, and modeling techniques that are used to design and support the operation of unique rocket propulsion test facilities.

  3. Transportation Secure Data Center: Real-World Data for Environmental and Air Quality Analysis (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2013-01-01

    The National Renewable Energy Laboratory (NREL) and the U.S. Department of Transportation (DOT) have launched the free, web-based Transportation Secure Data Center (TSDC). The TSDC (www.nrel.gov/tsdc) preserves respondent anonymity while making vital transportation data available to a broad group of users through secure, online access. The TSDC database provides free-of-charge web-based access to valuable transportation data that can be used for: Emissions and air pollution modeling, Vehicle energy and power analysis, Climate change impact studies, Alternative fuel station planning, and Validating transportation data from other sources. The TSDC's two levels of access make composite data available with simple online registration, and allow researchers to use detailed spatial data after completing a straight forward application process.

  4. Analysis of Parallelogram Mechanism used to Preserve Remote Center of Motion for Surgical Telemanipulator

    Directory of Open Access Journals (Sweden)

    Trochimczuk R.

    2017-02-01

    Full Text Available This paper presents an analysis of a parallelogram mechanism commonly used to provide a kinematic remote center of motion in surgical telemanipulators. Selected types of parallel manipulator designs, encountered in commercial and laboratory-made designs described in the medical robotics literature, will serve as the research material. Among other things, computer simulations in the ANSYS 13.0 CAD/CAE software environment, employing the finite element method, will be used. The kinematics of the solution of manipulator with the parallelogram mechanism will be determined in order to provide a more complete description. These results will form the basis for the decision regarding the possibility of applying a parallelogram mechanism in an original prototype of a telemanipulator arm.

  5. Transportation Secure Data Center: Real-World Data for Planning, Modeling, and Analysis

    Energy Technology Data Exchange (ETDEWEB)

    2017-01-01

    The Transportation Secure Data Center (TSDC) provides free, web-based access to detailed transportation data from a variety of travel surveys conducted across the nation. Maintained by the National Renewable Energy Laboratory (NREL) in partnership with the U.S. Department of Transportation (DOT), the TSDC houses data from travel surveys and studies conducted using GPS devices. It features millions of data points -- second-by-second GPS readings, vehicle characteristics (if applicable), and demographics -- for all modes of travel. NREL screens the initial data for quality control, translates each data set into a consistent format, and interprets the data for spatial analysis. NREL's processing routines add information on vehicle fuel economy and road grades and join data points to the road network.

  6. Analysis of Parallelogram Mechanism used to Preserve Remote Center of Motion for Surgical Telemanipulator

    Science.gov (United States)

    Trochimczuk, R.

    2017-02-01

    This paper presents an analysis of a parallelogram mechanism commonly used to provide a kinematic remote center of motion in surgical telemanipulators. Selected types of parallel manipulator designs, encountered in commercial and laboratory-made designs described in the medical robotics literature, will serve as the research material. Among other things, computer simulations in the ANSYS 13.0 CAD/CAE software environment, employing the finite element method, will be used. The kinematics of the solution of manipulator with the parallelogram mechanism will be determined in order to provide a more complete description. These results will form the basis for the decision regarding the possibility of applying a parallelogram mechanism in an original prototype of a telemanipulator arm.

  7. Activity of the CNES/CLS Analysis Center for the IDS contribution to ITRF2014

    Science.gov (United States)

    Soudarin, Laurent; Capdeville, Hugues; Lemoine, Jean-Michel

    2016-12-01

    Within the frame of the International DORIS Service, the CNES/CLS Analysis Center, previously known as LCA and renamed GRG, contributes to the geodetic and geophysical research activity through DORIS data analysis. The main work carried out in the past two years concerns the processing of the measurements collected by the DORIS-equipped satellites over 22 years, in order to provide a homogeneous series of station coordinates and Earth pole parameters for the IDS contribution to the ITRF2014. First, we brought several upgrades to the processing and the modeling. Some of them are corrective actions to issues raised during or shortly after the production of our contribution to the ITRF2008 (ground station frequency offsets, attitude laws and macromodels). Recent models have been assessed with the aim to update our analysis configuration. Among others, we adopted the time variable gravity (TVG) model EIGEN-6S2 and applied tropospheric gradients. Then we processed almost all the DORIS data collected between January 1993 and December 2014. The series of weekly SINEX solutions derived from this processing is labeled grgwd40. This new series performs better than the series produced for ITRF2008. Especially, the results discussed in this paper show a decrease of 2% of the DORIS orbit residuals as well as a strong reduction of the annual terms of the TRF scale and Tz translation which can be explained by the application of the TVG model.

  8. Investigating student communities with network analysis of interactions in a physics learning center

    Science.gov (United States)

    Brewe, Eric; Kramer, Laird; Sawtelle, Vashti

    2012-06-01

    Developing a sense of community among students is one of the three pillars of an overall reform effort to increase participation in physics, and the sciences more broadly, at Florida International University. The emergence of a research and learning community, embedded within a course reform effort, has contributed to increased recruitment and retention of physics majors. We utilize social network analysis to quantify interactions in Florida International University’s Physics Learning Center (PLC) that support the development of academic and social integration. The tools of social network analysis allow us to visualize and quantify student interactions and characterize the roles of students within a social network. After providing a brief introduction to social network analysis, we use sequential multiple regression modeling to evaluate factors that contribute to participation in the learning community. Results of the sequential multiple regression indicate that the PLC learning community is an equitable environment as we find that gender and ethnicity are not significant predictors of participation in the PLC. We find that providing students space for collaboration provides a vital element in the formation of a supportive learning community.

  9. Funding Opportunity: Genomic Data Centers

    Science.gov (United States)

    Funding Opportunity CCG, Funding Opportunity Center for Cancer Genomics, CCG, Center for Cancer Genomics, CCG RFA, Center for cancer genomics rfa, genomic data analysis network, genomic data analysis network centers,

  10. A Data Analysis Center for Electromagnetic and Hadronic Interaction. Products of the DAC members

    Energy Technology Data Exchange (ETDEWEB)

    Briscoe, William John [George Washington Univ., Washington, DC (United States); Strakovsky, Igor I. [George Washington Univ., Washington, DC (United States); Workman, Ronald L. [George Washington Univ., Washington, DC (United States)

    2015-08-31

    The Data Analysis Center (DAC) of the Center for Nuclear Studies (CNS) at the George Washington University (GW) has made significant progress in its program to enhance and expand the partial-wave (and multipole) analyses of fundamental two- and three-body reactions (such as pion-nucleon, photon-nucleon, and nucleon-nucleon scattering) by maintaining and augmenting the analysis codes and databases associated with these reactions. These efforts provide guidance to experimental groups at the international level, forming an important link between theory and experiment. A renaissance in light hadron spectroscopy is underway as a continuous stream of polarization data issues from existing precision electromagnetic facilities and the coming Jefferson Lab 12 GeV Upgrade. Our principal goals have been focused on supporting the national N* resonance physics program. We have also continued to study topics more generally related to the problems associated with partial-wave analysis. On the Experimental side of the CNS DAC. Its primary goal is the enhancement of the body of data necessary for our analyses of fundamental γ - N reactions. We perform experiments that study the dynamics responsible for the internal structure of the nucleon and its excitations. Our principal focus is on the N* programs at JLab and MAMI. At JLab we study spin-polarization observables using polarized photons, protons and neutrons and yielding charged final states. Similarly at MAMI we study neutral meson photoproduction off polarized protons and neutrons. We use the Crystal Ball and TAPS spectrometers (CBT) to detect photons and neutrons to measure the photoproduction of π0, η, 2π0, π0η, and K0 off the neutron. The CBT program complements our program at JLab, which studies reactions resulting in charged final states. We are also involved in a renewed effort to make neutral pion photoproduction measurements close to threshold at Mainz. In addition to the programs underway, we are contributing to

  11. Chemical analysis of World Trade Center fine particulate matter for use in toxicologic assessment.

    Science.gov (United States)

    McGee, John K; Chen, Lung Chi; Cohen, Mitchell D; Chee, Glen R; Prophete, Colette M; Haykal-Coates, Najwa; Wasson, Shirley J; Conner, Teri L; Costa, Daniel L; Gavett, Stephen H

    2003-06-01

    The catastrophic destruction of the World Trade Center (WTC) on 11 September 2001 caused the release of high levels of airborne pollutants into the local environment. To assess the toxicity of fine particulate matter [particulate matter with a mass median aerodynamic diameter fraction was isolated on filters. Here we report the chemical and physical properties of PM2.5 derived from these samples and compare them with PM2.5 fractions of three reference materials that range in toxicity from relatively inert to acutely toxic (Mt. St. Helens PM; Washington, DC, ambient air PM; and residual oil fly ash). X-ray diffraction of very coarse sieved WTC PM (fraction. Analysis of WTC PM2.5 using X-ray fluorescence, neutron activation analysis, and inductively coupled plasma spectrometry showed high levels of calcium (range, 22-33%) and sulfur (37-43% as sulfate) and much lower levels of transition metals and other elements. Aqueous extracts of WTC PM2.5 were basic (pH range, 8.9-10.0) and had no evidence of significant bacterial contamination. Levels of carbon were relatively low, suggesting that combustion-derived particles did not form a significant fraction of these samples recovered in the immediate aftermath of the destruction of the towers. Because gypsum and calcite are known to cause irritation of the mucus membranes of the eyes and respiratory tract, inhalation of high doses of WTC PM2.5 could potentially cause toxic respiratory effects.

  12. Detailed abundance analysis of a metal-poor giant in the Galactic Center

    CERN Document Server

    Ryde, N; Rich, R M; Thorsbro, B; Schultheis, M; Origlia, L; Chatzopoulos, S

    2016-01-01

    We report the first results from our program to examine the metallicity distribution of the Milky Way nuclear star cluster connected to SgrA*, with the goal of inferring the star formation and enrichment history of this system, as well as its connection and relationship with the central 100 pc of the bulge/bar system. We present the first high resolution (R~24,000), detailed abundance analysis of a K=10.2 metal-poor, alpha-enhanced red giant projected at 1.5 pc from the Galactic Center, using NIRSPEC on Keck II. A careful analysis of the dynamics and color of the star locates it at about 26 pc line-of-sight distance in front of the nuclear cluster. It probably belongs to one of the nuclear components (cluster or disk), not to the bar-bulge or classical disk. A detailed spectroscopic synthesis, using a new linelist in the K band, finds [Fe/H]~-1.0 and [alpha/Fe]~+0.4, consistent with stars of similar metallicity in the bulge. As known giants with comparable [Fe/H] and alpha enhancement are old, we conclude tha...

  13. NASA Johnson Space Center Usability Testing and Analysis facility (UTAF) Overview

    Science.gov (United States)

    Whitmore, Mihriban; Holden, Kritina L.

    2005-01-01

    The Usability Testing and Analysis Facility (UTAF) is part of the Space Human Factors Laboratory at the NASA Johnson Space Center in Houston, Texas. The facility performs research for NASA's HumanSystems Integration Program, under the HumanSystems Research and Technology Division. Specifically, the UTAF provides human factors support for space vehicles, including the International Space Station, the Space Shuttle, and the forthcoming Crew Exploration Vehicle. In addition, there are ongoing collaborative research efforts with external corporations and universities. The UTAF provides human factors analysis, evaluation, and usability testing of crew interfaces for space applications. This includes computer displays and controls, workstation systems, and work environments. The UTAF has a unique mix of capabilities, with a staff experienced in both cognitive human factors and ergonomics. The current areas of focus are: human factors applications in emergency medical care and informatics; control and display technologies for electronic procedures and instructions; voice recognition in noisy environments; crew restraint design for unique microgravity workstations; and refinement of human factors processes and requirements. This presentation will provide an overview of ongoing activities, and will address how the UTAF projects will evolve to meet new space initiatives.

  14. NASA Johnson Space Center Usability Testing and Analysis Facility (WAF) Overview

    Science.gov (United States)

    Whitmore, M.

    2004-01-01

    The Usability Testing and Analysis Facility (UTAF) is part of the Space Human Factors Laboratory at the NASA Johnson Space Center in Houston, Texas. The facility provides support to the Office of Biological and Physical Research, the Space Shuttle Program, the International Space Station Program, and other NASA organizations. In addition, there are ongoing collaborative research efforts with external businesses and universities. The UTAF provides human factors analysis, evaluation, and usability testing of crew interfaces for space applications. This includes computer displays and controls, workstation systems, and work environments. The UTAF has a unique mix of capabilities, with a staff experienced in both cognitive human factors and ergonomics. The current areas of focus are: human factors applications in emergency medical care and informatics; control and display technologies for electronic procedures and instructions; voice recognition in noisy environments; crew restraint design for unique microgravity workstations; and refinement of human factors processes. This presentation will provide an overview of ongoing activities, and will address how the projects will evolve to meet new space initiatives.

  15. Stirling Convertor Extended Operation Testing and Data Analysis at Glenn Research Center

    Science.gov (United States)

    Cornell, Peggy A.; Lewandowski, Edward J.; Oriti, Salvatore M.; Wilson, Scott D.

    2010-01-01

    Extended operation of Stirling convertors is essential to the development of radioisotope power systems and their potential use for longduration missions. To document the reliability of the convertors, regular monitoring and analysis of the extended operation data is particularly valuable, allowing us to better understand and quantify long-life characteristics of the convertors. Furthermore, investigation and comparison of the extended operation data to baseline performance data provides an opportunity to understand system behavior should any off-nominal performance occur. Glenn Research Center (GRC) has tested 16 Stirling convertors under 24-hr unattended extended operation, including four that have operated in a thermal vacuum environment and two that are operating in the Advanced Stirling Radioisotope Generator Engineering Unit. Ten of the sixteen convertors are the Advanced Stirling Convertors (ASC) developed by Sunpower, Inc. with GRC. These are highly efficient (conversion efficiency of up to 38 percent for the ASC-1), low-mass convertors that have evolved through technologically progressive convertor builds. Six convertors at GRC are Technology Demonstration Convertors from Infinia Corporation. They have achieved greater than 27 percent conversion efficiency and have accumulated over 185,000 of the total 265,000 hr of extended operation at GRC. This paper presents the extended operation testing and data analysis of free-piston Stirling convertors at NASA GRC as well as how these tests have contributed to the Stirling convertor s progression toward flight.

  16. CoryneCenter – An online resource for the integrated analysis of corynebacterial genome and transcriptome data

    Directory of Open Access Journals (Sweden)

    Hüser Andrea T

    2007-11-01

    Full Text Available Abstract Background The introduction of high-throughput genome sequencing and post-genome analysis technologies, e.g. DNA microarray approaches, has created the potential to unravel and scrutinize complex gene-regulatory networks on a large scale. The discovery of transcriptional regulatory interactions has become a major topic in modern functional genomics. Results To facilitate the analysis of gene-regulatory networks, we have developed CoryneCenter, a web-based resource for the systematic integration and analysis of genome, transcriptome, and gene regulatory information for prokaryotes, especially corynebacteria. For this purpose, we extended and combined the following systems into a common platform: (1 GenDB, an open source genome annotation system, (2 EMMA, a MAGE compliant application for high-throughput transcriptome data storage and analysis, and (3 CoryneRegNet, an ontology-based data warehouse designed to facilitate the reconstruction and analysis of gene regulatory interactions. We demonstrate the potential of CoryneCenter by means of an application example. Using microarray hybridization data, we compare the gene expression of Corynebacterium glutamicum under acetate and glucose feeding conditions: Known regulatory networks are confirmed, but moreover CoryneCenter points out additional regulatory interactions. Conclusion CoryneCenter provides more than the sum of its parts. Its novel analysis and visualization features significantly simplify the process of obtaining new biological insights into complex regulatory systems. Although the platform currently focusses on corynebacteria, the integrated tools are by no means restricted to these species, and the presented approach offers a general strategy for the analysis and verification of gene regulatory networks. CoryneCenter provides freely accessible projects with the underlying genome annotation, gene expression, and gene regulation data. The system is publicly available at http://www.CoryneCenter.de.

  17. Clinical analysis of pediatric patients who visited Masan Samsung Emergency Center

    Directory of Open Access Journals (Sweden)

    Jae Wook Yoo

    2010-03-01

    Full Text Available Purpose : Through a clinical and retrospective analysis of pediatric patients who visited the Regional Emergency Medical Center of Masan Samsung Hospital from January 2007 to December 2008, we characterized pediatric and adolescent emergency patients to improve emergency care in future. Methods : We reviewed the medical records of 14,065 pediatric patients below 19 years of age. Results : The male to female ratio was 1.5:1, and the most common age group was less than 3 years (49.6%. The peak month was May (10.0%, the peak day of the week was Sunday (24.7%, and the peak time of day was 20:00–20:59 (8.5%. There was no difference in the number of visits per day based on weather (sunny, rain [below 10 mm per day], snow, and fog or daily temperature difference; however, visits increased on sandy, dusty days and decreased on rainy days with more than 10 mm of rain per day. Based on the international classification of disease (ICD-10 system, the most common disease code was code R (symptoms, sign, and abnormal clinical laboratory finding (31.5%, and the most common symptom was fever (13.1%. Final outcomes were discharged (73.8%, admitted (25.7%, transferred (0.4%, and expired (0.1%. In adolescent patients aged 15–19 years, the most common disease code was Injury & Poisoning (code S&T, 36.9%; the most common symptom was abdominal pain (9.6%. Conclusion : Pediatric patients visiting the emergency center were most likely to be male and under 3 years of age and to visit between 20:00 and 21:00 on Sundays and in May, and the most common symptom was fever. Differences between adolescents and pediatric patients showed that adolescents had a higher visiting rate with abdominal pain and a larger temperature difference.

  18. Analysis of the access patterns at GSFC distributed active archive center

    Science.gov (United States)

    Johnson, Theodore; Bedet, Jean-Jacques

    1996-01-01

    The Goddard Space Flight Center (GSFC) Distributed Active Archive Center (DAAC) has been operational for more than two years. Its mission is to support existing and pre Earth Observing System (EOS) Earth science datasets, facilitate the scientific research, and test Earth Observing System Data and Information System (EOSDIS) concepts. Over 550,000 files and documents have been archived, and more than six Terabytes have been distributed to the scientific community. Information about user request and file access patterns, and their impact on system loading, is needed to optimize current operations and to plan for future archives. To facilitate the management of daily activities, the GSFC DAAC has developed a data base system to track correspondence, requests, ingestion and distribution. In addition, several log files which record transactions on Unitree are maintained and periodically examined. This study identifies some of the users' requests and file access patterns at the GSFC DAAC during 1995. The analysis is limited to the subset of orders for which the data files are under the control of the Hierarchical Storage Management (HSM) Unitree. The results show that most of the data volume ordered was for two data products. The volume was also mostly made up of level 3 and 4 data and most of the volume was distributed on 8 mm and 4 mm tapes. In addition, most of the volume ordered was for deliveries in North America although there was a significant world-wide use. There was a wide range of request sizes in terms of volume and number of files ordered. On an average 78.6 files were ordered per request. Using the data managed by Unitree, several caching algorithms have been evaluated for both hit rate and the overhead ('cost') associated with the movement of data from near-line devices to disks. The algorithm called LRU/2 bin was found to be the best for this workload, but the STbin algorithm also worked well.

  19. Analysis of Conflict Centers in Projects Procured with Traditional and Integrated Methods in Nigeria

    Directory of Open Access Journals (Sweden)

    Martin O. Dada

    2012-07-01

    Full Text Available Conflicts in any organization can either be functional or dysfunctional and can contribute to or detract from the achievement of organizational or project objectives. This study investigated the frequency and intensity of conflicts, using five conflict centers, on projects executed with either the integrated or traditional method in Nigeria. Questionnaires were administered through purposive and snowballing techniques on 274 projects located in twelve states of Nigeria and Abuja. 94 usable responses were obtained. The collected data were subjected to both descriptive and inferential statistical analysis. In projects procured with traditional methods, conflicts relating to resources for project execution had the greatest frequency, while conflicts around project/client goals had the least frequency. For projects executed with integrated methods, conflicts due to administrative procedures were ranked highest while conflicts due to project/client goals were ranked least. Regarding seriousness of conflict, conflicts due to administrative procedures and resources for project execution were ranked highest respectively for projects procured with traditional and integrated methods. Additionally, in terms of seriousness, personality issues and project/client goals were the least sources of conflict in projects executed with traditional and integrated methods. There were no significant differences in the incidence of conflicts, using the selected conflict centers, between the traditional and integrated procurement methods. There was however significant difference in the intensity or seriousness of conflicts between projects executed with the traditional method and those executed with integrated methods in the following areas: technical issues, administrative matters and personality issues. The study recommends that conscious efforts should be made at teambuilding on projects executed with integrated methods.

  20. Activation Strain Analysis of SN2 Reactions at C, N, O, and F Centers.

    Science.gov (United States)

    Kubelka, Jan; Bickelhaupt, F Matthias

    2017-02-02

    Fundamental principles that determine chemical reactivity and reaction mechanisms are the very foundation of chemistry and many related fields of science. Bimolecular nucleophilic substitutions (SN2) are among the most common and therefore most important reaction types. In this report, we examine the trends in the SN2 reactions with respect to increasing electronegativity of the reaction center by comparing the well-studied backside SN2 Cl(-) + CH3Cl with similar Cl(-) substitutions on the isoelectronic series with the second period elements N, O, and F in place of C. Relativistic (ZORA) DFT calculations are used to construct the gas phase reaction potential energy surfaces (PES), and activation strain analysis, which allows decomposition of the PES into the geometrical strain and interaction energy, is employed to analyze the observed trends. We find that SN2@N and SN2@O have similar PES to the prototypical SN2@C, with the well-defined reaction complex (RC) local minima and a central barrier, but all stationary points are, respectively, increasingly stable in energy. The SN2@F, by contrast, exhibits only a single-well PES with no barrier. Using the activation strain model, we show that the trends are due to the interaction energy and originate mainly from the decreasing energy of the empty acceptor orbital (σ*A-Cl) on the reaction center A in the order of C, N, O, and F. The decreasing steric congestion around the central atom is also a likely contributor to this trend. Additional decomposition of the interaction energy using Kohn-Sham molecular orbital (KS-MO) theory provides further support for this explanation, as well as suggesting electrostatic energy as the primary reason for the distinct single-well PES profile for the FCl reaction.

  1. A COMPARATIVE ANALYSIS OF OBSTETRIC REFERRALS THAT ARE REFERRED TO THE TERITIARY CARE CENTER

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    Shailaja

    2015-10-01

    Full Text Available AIM: To evaluate the obstetric referrals to the tertiary center in the current year and to compare the data to the referrals 20 years ago. MATERIALS AND METHODS: This is a retrospective analysis under taken in the Department of OB G, for a period of six months in 2012 - 13 at King George Hospital Visakhapatnam. Data from Medical records during the same months in 1992 - 1993 were obtained. Data of 2012 - 2013 is considered as group - B and data of 1992 - 1993 as group - A. Both are analyzed and compared. RESULTS: Referrals of group - B constituted 51.76% of all the emergency admissions, of which 69.30% were antenatal women. 51.68% were referred in the night between 8pm - 8am. 90.84% were referred from government institutions. Maternal deaths were three and perinatal mortality 35.2%. DISCUSSION: Referrals in the last 20 years increased from 31.64% to 51.76%. In group - B 69.30% were antenatal where as in group A, 81.31% of referrals were in labour. Almost all women were referred in the night in group A. Perinatal mortali ty in group - A was higher (42.54%. CONCLUSION: Under NRHM, and through EmOC program the medical officers of PHCs are trained and infra - structure is being up graded. Hence high risk obstetric women are being identified and are referred earlier. 38.49% of th e women are referred only for conduct of c - section from CHCs and area hospitals in the recent times, where facilities for c - section are supposed to be available. Problems in performing C sections in these centers have to be addressed.

  2. Regional Gray Matter Atrophy in Relapsing Remitting Multiple Sclerosis: Baseline Analysis of Multi-Center Data

    Science.gov (United States)

    Datta, Sushmita; Staewen, Terrell D.; Cofield, Stacy S.; Cutter, Gary R.; Lublin, Fred D.; Wolinsky, Jerry S.; Narayana, Ponnada A.

    2015-01-01

    Regional gray matter (GM) atrophy in multiple sclerosis (MS) at disease onset and its temporal variation can provide objective information regarding disease evolution. An automated pipeline for estimating atrophy of various GM structures was developed using tensor based morphometry (TBM) and implemented on a multi-center sub-cohort of 1008 relapsing remitting MS (RRMS) patients enrolled in a Phase 3 clinical trial. Four hundred age and gender matched healthy controls were used for comparison. Using the analysis of covariance, atrophy differences between MS patients and healthy controls were assessed on a voxel-by-voxel analysis. Regional GM atrophy was observed in a number of deep GM structures that included thalamus, caudate nucleus, putamen, and cortical GM regions. General linear regression analysis was performed to analyze the effects of age, gender, and scanner field strength, and imaging sequence on the regional atrophy. Correlations between regional GM volumes and expanded disability status scale (EDSS) scores, disease duration (DD), T2 lesion load (T2 LL), T1 lesion load (T1 LL), and normalized cerebrospinal fluid (nCSF) were analyzed using Pearson’s correlation coefficient. Thalamic atrophy observed in MS patients compared to healthy controls remained consistent within subgroups based on gender and scanner field strength. Weak correlations between thalamic volume and EDSS (r = −0.133; p < 0.001) and DD (r = −0.098; p = 0.003) were observed. Of all the structures, thalamic volume moderately correlated with T2 LL (r = −0.492; p-value < 0.001), T1 LL (r = −0.473; p-value < 0.001) and nCSF (r = −0.367; p-value < 0.001). PMID:25787188

  3. Regional gray matter atrophy in relapsing remitting multiple sclerosis: baseline analysis of multi-center data.

    Science.gov (United States)

    Datta, Sushmita; Staewen, Terrell D; Cofield, Stacy S; Cutter, Gary R; Lublin, Fred D; Wolinsky, Jerry S; Narayana, Ponnada A

    2015-03-01

    Regional gray matter (GM) atrophy in multiple sclerosis (MS) at disease onset and its temporal variation can provide objective information regarding disease evolution. An automated pipeline for estimating atrophy of various GM structures was developed using tensor based morphometry (TBM) and implemented on a multi-center sub-cohort of 1008 relapsing remitting MS (RRMS) patients enrolled in a Phase 3 clinical trial. Four hundred age and gender matched healthy controls were used for comparison. Using the analysis of covariance, atrophy differences between MS patients and healthy controls were assessed on a voxel-by-voxel analysis. Regional GM atrophy was observed in a number of deep GM structures that included thalamus, caudate nucleus, putamen, and cortical GM regions. General linear regression analysis was performed to analyze the effects of age, gender, and scanner field strength, and imaging sequence on the regional atrophy. Correlations between regional GM volumes and expanded disability status scale (EDSS) scores, disease duration (DD), T2 lesion load (T2 LL), T1 lesion load (T1 LL), and normalized cerebrospinal fluid (nCSF) were analyzed using Pearson׳s correlation coefficient. Thalamic atrophy observed in MS patients compared to healthy controls remained consistent within subgroups based on gender and scanner field strength. Weak correlations between thalamic volume and EDSS (r=-0.133; p<0.001) and DD (r=-0.098; p=0.003) were observed. Of all the structures, thalamic volume moderately correlated with T2 LL (r=-0.492; P-value<0.001), T1 LL (r=-0.473; P-value<0.001) and nCSF (r=-0.367; P-value<0.001).

  4. Effectiveness of person-centered care on people with dementia: a systematic review and meta-analysis

    Science.gov (United States)

    Kim, Sun Kyung; Park, Myonghwa

    2017-01-01

    Background Person-centered care is a holistic and integrative approach designed to maintain well-being and quality of life for people with dementia, and it includes the elements of care, the individual, the carers, and the family. Aim A systematic literature review and meta-analysis were undertaken to investigate the effectiveness of person-centered care for people with dementia. Methods Literature searches were undertaken using six databases including Medline, EMBASE, CINAHL, PsycINFO, Cochrane Database, and KoreaMed using the following keywords: cognition disorder, dementia, person-centered care, patient-centered care, client-centered care, relationship-centered care, and dementia care. The searches were limited to interventional studies written in English and Korean and included randomized controlled studies and noncontrolled studies for people with dementia living in any setting. Results Nineteen interventional studies, including 3,985 participants, were identified. Of these, 17 studies were from long-term care facilities and two studies were from homecare settings. The pooled data from randomized controlled studies favored person-centered care in reducing agitation, neuropsychiatric symptoms, and depression and improving the quality of life. Subgroup analysis identified greater effectiveness of person-centered care when implemented for people with less severe dementia. For agitation, short-term interventions had a greater effect (standardized mean difference [SMD]: −0.434; 95% conference interval [CI]: −0.701 to −0.166) than long-term interventions (SMD: −0.098; 95% CI: −0.190 to 0.007). Individualized activities resulted in a significantly greater beneficial effect than standard care (SMD: 0.513; 95% CI: −0.994 to −0.032). However, long-term, staff education, and cultural change interventions had a greater effect on improving the quality of life for people with dementia (SMD: 0.191; 95% CI: 0.079 to 0.302). Conclusion This systematic review and

  5. Assessment of mold concentrations in Singapore shopping centers using mold-specific quantitative PCR (MSQPCR) analysis.

    Science.gov (United States)

    Yap, Jennifer; Toh, Zhen Ann; Goh, Vivien; Ng, Lee Chen; Vesper, Stephen

    2009-09-01

    Molds can pose a human health threat and may amplify in buildings in humid climates. The objective of this study was to evaluate the mold growth in Singapore shopping centers based on the collection of 40 dust samples from 15 shopping centers, including one with a history of water damage. The dust was analyzed by a DNA-based technology called mold-specific quantitative PCR (MSQPCR). In a water-damaged shopping center, most of the 26 water-damage indicator species were detected at some concentration and many were much more abundant than the average in the shopping centers. MSQPCR is a useful method for quantifying indoor molds in tropical climates.

  6. Reliability centered maintenance (RCM: quantitative analysis of an induction electric furnace

    Directory of Open Access Journals (Sweden)

    Diego Santos Cerveira

    2015-06-01

    Full Text Available The purpose of this article is to define a maintenance strategy for an electric induction furnace, installed on a special steels Foundry. The research method was the quantitative modeling. The proposed method is based on Reliability-Centered Maintenance (RCM, applied to industrial equipment. Quantitative analysis of reliability, availability and maintainability were used as support the definition of the maintenance strategy of the equipment. For research, historical data were collected from time-to-repair (TTR and time between failures (TBF of the equipment under consideration. Supported by ProConf 2000 software, most appropriate distributions have been identified and modeled to TTR (lognormal and TBF (Weibull. With the results, availability of equipment Av = 98,18% and form factor g = 1 of the Weibull distribution were calculated. It was possible to find a position for the equipment on the bathtub curve, in the maturity phase and define the best maintenance strategy for this case, the predictive maintenance. Finally, the current strategy was discussed and development suggestions were presented to this strategy.

  7. Imprinting center analysis in Prader-Willi and Angelman syndrome patients with typical and atypical phenotypes.

    Science.gov (United States)

    Camprubí, Cristina; Coll, Maria Dolors; Villatoro, Sergi; Gabau, Elisabeth; Kamli, Amine; Martínez, Maria Jesus; Poyatos, David; Guitart, Miriam

    2007-01-01

    Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are genetic disorders caused by a deficiency of imprinted gene expression from the paternal or maternal chromosome 15, respectively. This deficiency is due to the deletion of the 15q11-q13 region, parental uniparental disomy of the chromosome 15, or imprinting defect (ID). Mutation of the UBE3A gene causes approximately 10% of AS cases. In this present study, we describe the molecular analysis and phenotypes of two PWS patients and four AS patients with ID. One of the PWS patients has a non-familial imprinting center (IC) deletion and displayed a severe phenotype with an atypical PWS appearance, hyperactivity and psychiatric vulnerability. The other PWS and AS patients did not present genetic abnormalities in the IC, suggesting an epimutation as the genetic cause. The methylation pattern of two AS patients showed a faint maternal band corresponding to a mosaic ID. One of these mosaic patients displayed a mild AS phenotype while the other displayed a PWS-like phenotype.

  8. Models and applications for space weather forecasting and analysis at the Community Coordinated Modeling Center.

    Science.gov (United States)

    Kuznetsova, Maria

    The Community Coordinated Modeling Center (CCMC, http://ccmc.gsfc.nasa.gov) was established at the dawn of the new millennium as a long-term flexible solution to the problem of transition of progress in space environment modeling to operational space weather forecasting. CCMC hosts an expanding collection of state-of-the-art space weather models developed by the international space science community. Over the years the CCMC acquired the unique experience in preparing complex models and model chains for operational environment and developing and maintaining custom displays and powerful web-based systems and tools ready to be used by researchers, space weather service providers and decision makers. In support of space weather needs of NASA users CCMC is developing highly-tailored applications and services that target specific orbits or locations in space and partnering with NASA mission specialists on linking CCMC space environment modeling with impacts on biological and technological systems in space. Confidence assessment of model predictions is an essential element of space environment modeling. CCMC facilitates interaction between model owners and users in defining physical parameters and metrics formats relevant to specific applications and leads community efforts to quantify models ability to simulate and predict space environment events. Interactive on-line model validation systems developed at CCMC make validation a seamless part of model development circle. The talk will showcase innovative solutions for space weather research, validation, anomaly analysis and forecasting and review on-going community-wide model validation initiatives enabled by CCMC applications.

  9. Impact of aprotinin and renal function on mortality: a retrospective single center analysis

    Directory of Open Access Journals (Sweden)

    Von Visger Jon

    2011-08-01

    Full Text Available Abstract Background An estimated up to 7% of high-risk cardiac surgery patients return to the operating room for bleeding. Aprotinin was used extensively as an antifibrinolytic agent in cardiac surgery patients for over 15 years and it showed efficacy in reducing bleeding. Aprotinin was removed from the market by the U.S. Food and Drug Administration after a large prospective, randomized clinical trial documented an increased mortality risk associated with the drug. Further debate arose when a meta-analysis of 211 randomized controlled trials showed no risk of renal failure or death associated with aprotinin. However, only patients with normal kidney function have been studied. Methods In this study, we look at a single center clinical trial using patients with varying degrees of baseline kidney function to answer the question: Does aprotinin increase odds of death given varying levels of preoperative kidney dysfunction? Results Based on our model, aprotinin use was associated with a 3.8-fold increase in odds of death one year later compared to no aprotinin use with p-value = 0.0018, regardless of level of preoperative kidney dysfunction after adjusting for other perioperative variables. Conclusions Lessons learned from our experience using aprotinin in the perioperative setting as an antifibrinolytic during open cardiac surgery should guide us in testing future antifibrinolytic drugs for not only efficacy of preventing bleeding, but for overall safety to the whole organism using long-term clinical outcome studies, including those with varying degree of baseline kidney function.

  10. Impact of aprotinin and renal function on mortality: a retrospective single center analysis.

    Science.gov (United States)

    Schloss, Brian; Gulati, Parul; Yu, Lianbo; Abdel-Rasoul, Mahmoud; O'Brien, William; Von Visger, Jon; Awad, Hamdy

    2011-08-30

    An estimated up to 7% of high-risk cardiac surgery patients return to the operating room for bleeding. Aprotinin was used extensively as an antifibrinolytic agent in cardiac surgery patients for over 15 years and it showed efficacy in reducing bleeding. Aprotinin was removed from the market by the U.S. Food and Drug Administration after a large prospective, randomized clinical trial documented an increased mortality risk associated with the drug. Further debate arose when a meta-analysis of 211 randomized controlled trials showed no risk of renal failure or death associated with aprotinin. However, only patients with normal kidney function have been studied. In this study, we look at a single center clinical trial using patients with varying degrees of baseline kidney function to answer the question: Does aprotinin increase odds of death given varying levels of preoperative kidney dysfunction? Based on our model, aprotinin use was associated with a 3.8-fold increase in odds of death one year later compared to no aprotinin use with p-value = 0.0018, regardless of level of preoperative kidney dysfunction after adjusting for other perioperative variables. Lessons learned from our experience using aprotinin in the perioperative setting as an antifibrinolytic during open cardiac surgery should guide us in testing future antifibrinolytic drugs for not only efficacy of preventing bleeding, but for overall safety to the whole organism using long-term clinical outcome studies, including those with varying degree of baseline kidney function.

  11. Urinary stone analysis on 12,846 patients: a report from a single center in China.

    Science.gov (United States)

    Wu, Wenqi; Yang, Bicheng; Ou, Lili; Liang, Yeping; Wan, Shawpong; Li, Shujue; Zeng, Guohua

    2014-02-01

    We reported a retrospective review of the urinary stone compositions in 12,846 patients. Data on urinary stone compositions analyzed between January 2003 and December 2012 in our center were collected. Infrared spectroscopy was used for stone analysis. Predominant stone component was recorded. Patients were divided into four age groups: 0-18, 19-40, 41-60, and 61-92, and five categories by components. In order to determine the change of stone characteristics with respect to time, data were also divided into two periods, 2003-2007 and 2008-2012. A total of 12,846 stones were included in this study. The age of the patients ranged from 1 to 92 years with 7,736 males and 5,110 females. Stone made of single component was rare, 2.61%. Calcium oxalate stone was the most common component at 82.56%. Calcium oxalate and uric acid stones were more common in male than in female. The incidence of calcium phosphate stones and uric acid stones had increased during the past 5 years, while calcium oxalate stones decreased. We found the highest incidence of stone disease in the 41-60 years old group and the lowest in the 1-18 years old for both genders. Calcium oxalate was the dominant component in every group but was more prevalent in 19-40 years group. The percentage of magnesium ammonium phosphate stone and uric acid stone increased with age.

  12. A Person-Centered Examination of Adolescent Religiosity Using Latent Class Analysis

    Science.gov (United States)

    Pearce, Lisa D.; Foster, E. Michael; Hardie, Jessica Halliday

    2013-01-01

    Empirical studies of religion’s role in society, especially those focused on individuals and analyzing survey data, conceptualize and measure religiosity on a single measure or a summary index of multiple measures. Other concepts, such as “lived religion,” “believing without belonging,” or “fuzzy fidelity,” emphasize what scholars have noted for decades: humans are rarely consistently low, medium, or high across dimensions of religiosity including institutional involvement, private practice, salience, or belief. A method with great promise for identifying population patterns in how individuals combine types and levels of belief, practice, and personal religious salience is latent class analysis. In this paper, we use data from the first wave of the National Study of Youth and Religion’s telephone survey to discuss how to select indicators of religiosity in an informed manner, as well as the implications of the number and types of indicators used for model fit. We identify five latent classes of religiosity among adolescents in the United States and their socio-demographic correlates. Our findings highlight the value of a person-centered approach to understanding how religion is lived by American adolescents. PMID:24043905

  13. Long term Combination of Tide Gauge Benchmark Monitoring (TIGA) Analysis Center Products

    Science.gov (United States)

    Teferle, F. N.; Hunegnaw, A.

    2015-12-01

    The International GNSS Service (IGS) Tide Gauge Benchmark Monitoring (TIGA) Working Group (WG) has recently finallized their reprocessing campaign, using all relevant Global Positioning System (GPS) observations from 1995 to 2014. This re-processed dataset will provide high quality estimates of land motions, enabling regional and global high-precision geophysical/geodeticstudies. Several of the individual TIGA Analysis Centers (TACs) have completed processing the full history of GPS observations recorded by the IGS global network, as well as, many other GPS stationsat or close to tide gauges, which are available from the TIGA data centre at the University of La Rochelle (www.sonel.org). The TAC solutions contain a total of over 700 stations. Following the recentimprovements in processing models and strategies, this is the first complete reprocessing attempt by the TIGA WG to provide homogeneous position time series. The TIGA Combination Centre (TCC) atthe University of Luxembourg (UL) has computed a first multi-year weekly combined solution using two independent combination software packages: CATREF and GLOBK. These combinations allow anevaluation of any effects from the combination software and of the individual TAC contributions and their influences on the combined solution. In this study we will present the first UL TIGA multi-yearcombination results and discuss these in terms of geocentric sea level changes.

  14. Cervical necrotizing fasciitis: descriptive, retrospective analysis of 59 cases treated at a single center.

    Science.gov (United States)

    Elander, Johanna; Nekludov, Michael; Larsson, Agneta; Nordlander, Britt; Eksborg, Staffan; Hydman, Jonas

    2016-12-01

    To provide retrospective, descriptive information on patients with cervical necrotizing fasciitis treated at a single center during the years 1998-2014, and to evaluate the outcome of a newly introduced treatment strategy. Retrospective analysis of clinical data obtained from medical records. Mortality, pre-morbidity, severity of illness, primary site of infection, type of bacteria, time parameters. The observed 3-month mortality was 6/59 (10 %). The most common initial foci of the infection were pharyngeal, dental or hypopharyngeal. The most common pathogen was Streptococcus milleri bacteria within the Streptococcus anginosus group (66 % of the cases). Using a combined treatment with early surgical debridement combined with hyperbaric oxygen treatment, it is possible to reduce the mortality rate among patients suffering from cervical necrotizing fasciitis, compared to the expected mortality rate and to previous historical reports. Data indicated that early onset of hyperbaric oxygen treatment may have a positive impact on survival rate, but no identifiable factor was found to prognosticate outcome.

  15. Strategies in Using a Qualitative Database for the Analysis of Problem-centered Interviews

    Directory of Open Access Journals (Sweden)

    Thomas Kühn

    2000-12-01

    Full Text Available On the basis of several examples from our longitudinal study "Transitions to Employment," dealing with the shaping of biography of young adults and typical transition-patterns from education to employment, we discuss the use of a text databank in the evaluation of problem-centered interviews. First, we explain the structure of the project's "databank of biographical interviews with young adults" which is founded on a thematic and temporarily differentiating system of categories recording job- and family-related actions and orientations. We present different ways of using the databank in qualitative evaluation. The manner how certain cases and categories of the databank are selected and included in the analysis depends on the objective and the problem's complexity. Our examples show that the use of a databank is an important possibility to support the evaluation of qualitative interviews, facilitating a thematic directed access and thus allowing the handling of data which are particularly extensive. URN: urn:nbn:de:0114-fqs0003183

  16. Outcome analysis of management of liver trauma: A 10-year experience at a trauma center

    Institute of Scientific and Technical Information of China (English)

    Wong; Hoi; She; Tan; To; Cheung; Wing; Chiu; Dai; Simon; HY; Tsang; Albert; CY; Chan; Daniel; KH; Tong; Gilberto; KK; Leung; Chung; Mau; Lo

    2016-01-01

    AIM: To review the outcomes of liver trauma in patients with hepatic injuries only and in patients with associated injuries outside the liver.METHODS: Data of liver trauma patients presented to our center from January 2003 to October 2013 were reviewed. The patients were divided into two groups. Group 1 consisted of patients who had hepatic injuries only. Group 2 consisted of patients who also had associated injuries outside the liver.RESULTS: Seven(30.4%) patients in group 1 and 10(28.6%) patients in group 2 received non-operative management; the rest underwent operation. Blunt trauma occurred in 82.8%(48/58) of the patients and penetrative trauma in 17.2%(10/58). A higher injury severity score(ISS) was observed in group 2(median 45 vs 25, P < 0.0001). More patients in group 1 were hemodynamically stable(65.2% vs 37.1%, P = 0.036). Other parameters were comparable between groups. Group 1 had better 30-d survival(91.3% vs 71.4%, P = 0.045). On multivariate analysis using the logistic regression model, ISS was found to be associated with mortality(P = 0.004, hazard ratio = 1.035, 95%CI:CONCLUSION: Liver trauma patients with multiple injuries are relatively unstable on presentation. Despite a higher ISS in group 2, non-operative management was possible for selected patients. Associated injuries outside the liver usually account for morbidity and mortality.

  17. Python-Based Scientific Analysis and Visualization of Precipitation Systems at NASA Marshall Space Flight Center

    Science.gov (United States)

    Lang, Timothy J.

    2015-01-01

    larger regional or national picture of precipitating weather systems. Composites, horizontal and vertical crosssections, and combinations thereof are easily displayed using as little as one line of code. MMM-Py can also write to the native MRMS binary format, and sub-sectioning of tiles (or multiple stitched tiles) is anticipated to be in place by the time of this meeting. Thus, MMM-Py also can be used to power the creation of custom mosaics for targeted regional studies. Overlays of other data (e.g., lightning observations) are easily accomplished. Demonstrations of MMM-Py, including the creation of animations, will be shown. Finally, Marshall has done significant work to interface Python-based analysis routines with the U.S. Department of Energy's Py-ART software package for radar data ingest, processing, and analysis. One example of this is the Python Turbulence Detection Algorithm (PyTDA), an MSFC-based implementation of the National Center for Atmospheric Research (NCAR) Turbulence Detection Algorithm (NTDA) for the purposes of convective-scale analysis, situational awareness, and forensic meteorology. PyTDA exploits Py-ART's radar data ingest routines and data model to rapidly produce aviation-relevant turbulence estimates from Doppler radar data. Work toward processing speed optimization and better integration within the Py-ART framework will be highlighted. Python-based analysis within the Py-ART framework is also being done for new research related to intercomparison of ground-based radar data with satellite estimates of ocean winds, as well as research on the electrification of pyrocumulus clouds.

  18. Influence of embedding parameters and noise in center of pressure recurrence quantification analysis.

    Science.gov (United States)

    Hasson, Christopher J; Van Emmerik, Richard E A; Caldwell, Graham E; Haddad, Jeffrey M; Gagnon, Jeff L; Hamill, Joseph

    2008-04-01

    Recurrence quantification analysis (RQA) can extract the dynamics of postural control from center of pressure (CoP) data by quantifying the system's repeatability, complexity, and local dynamic stability through several variables. Computation of these variables requires the selection of suitable embedding parameters for state space reconstruction (i.e. time delay and embedding dimension); however, it is unclear how the parameters influence RQA variables when examining noisy CoP data. This study evaluated the sensitivity of RQA variables to embedding parameter values and noise level, and assessed methods of selecting embedding parameters for CoP data. Five healthy male subjects maintained quiet stance for 30s while the anterior-posterior CoP was measured. The effect of noise was evaluated by adding uniform white noise of increasing amplitude to the raw CoP signal. The magnitude of all RQA variables decreased with increasing noise amplitude for all subjects. A sensitivity analysis was performed by systematically altering the embedding parameters for the raw data with and without a selected level of added noise. The key result was that, for all subjects, the RQA variables were sensitive to the embedding parameter values and the level of noise in the CoP data. Finally, the performance of false nearest neighbors and average displacement algorithms for choosing embedding parameters was evaluated. Both methods gave clear and consistent results for all subjects with either raw or noisy data. The results suggest that careful selection of embedding parameters is essential when using RQA to examine postural control based on noisy CoP data.

  19. Analysis of periinterventional complications of intracranial angioplasty and stenting: A single center experience

    Energy Technology Data Exchange (ETDEWEB)

    Silber, Toni; Ziemann, Ulf [Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen (Germany); Ernemann, Ulrike [Department of Diagnostic and Interventional Neuroradiology, University of Tübingen (Germany); Bischof, Felix, E-mail: felix.bischof@uni-tuebingen.de [Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen (Germany)

    2014-12-15

    Highlights: • Periinterventional complications in 7.5% of patients with intracranial artery stenting. • 2.5% of periinterventional complications were perforator strokes. • 3.8% of patients developed a hemorrhagic stroke due to reperfusion injury. • Complications could be reduced by individualized measures to prevent perforator stroke or reperfusion injury. - Abstract: Background and purpose: Treatment of symptomatic intracranial atherosclerotic disease by angioplasty and stenting (PTAS) is limited by a high rate of periinterventional strokes. We performed a detailed analysis of these strokes at our center in order to identify strategies to reduce the risk of periinterventional complications. Methods: Case records and imaging data of 80 patients with a symptomatic 70–99% stenosis of a major intracranial artery treated with PTAS between July 2007 and December 2013 were reviewed. All patients had a sufficient response to aspirin and clopidogrel. Periinterventional strokes were categorized as either ischemic (perforator territory, distal embolic or delayed stent thrombosis) or hemorrhagic (intraparenchymal, subarachnoid). Results: Periinterventional complications occurred in 6/80 (7.5%) patients, consisting of 2 ischemic strokes (2.5%, both perforator territory), 3 hemorrhagic strokes (3.8%, 2 intraparenchymal due to reperfusion injury, 1 subarachnoid due to vessel rupture) and one death (1.3%) unrelated to stroke. All strokes occurred within 24 h after PTAS. Conclusion: Our retrospective data analysis suggests that the risk of periinterventional stroke after PTAS of symptomatic intracranial atherosclerotic disease might be reduced by sufficient antiplatelet therapy and optimized management of patients with high risk for reperfusion injury or perforator strokes, including selection of a stenting device adapted to individual vessel morphology.

  20. Analysis of admissions and outcomes in verified and nonverified burn centers.

    Science.gov (United States)

    Palmieri, Tina L; London, Jason A; O'Mara, Michael S; Greenhalgh, David G

    2008-01-01

    The American Burn Association instituted a burn center verification process to ensure optimal care for patients with burn injury. Limited data exist regarding differences in admissions and outcomes between verified (VC) and nonverified burn centers (NVC). The study purpose was to compare demographics, treatment, and outcomes of VC and NVC. The five VC were compared with the 12 NVC using data from California's discharge database for the year 2003. A total of 2867 patients were admitted to a burn center, 1645 to NVC (132/center), and 1222 (244/center) to VC. NVC admitted 1496 (91%) of their patients from local area and 118 (7%) from other acute care hospitals; in contrast, 948 (78%) of VC patients were local and 253 (21%) were transfers from other acute care hospitals. VCs admitted twice as many burns > or =80% total body surface area as NVC. VCs admitted more patients with face burns (18% VC vs 14% NVC, P NVC P NVC, P NVC and 4% in VC. During the study period verified centers in California admitted more patients per center and treated more severely injured patients than nonverified centers. Despite these differences, VC had mortality rates comparable to their nonverified counterparts. These findings support the need for additional studies evaluating the impact of verification on burn care.

  1. Predictors of PTSD symptoms in adults admitted to a Level I trauma center: A prospective analysis

    NARCIS (Netherlands)

    Powers, M.B.; Warren, A.M.; Rosenfield, D.; Roden-Foreman, K.; Bennett, M.; Reynolds, M.C.; Davis, M.L.; Foreman, M.; Petrey, L.B.; Smits, J.A.J.

    2014-01-01

    Trauma centers are an ideal point of intervention in efforts to prevent posttraumatic stress disorder (PTSD). In order to assist in the development of prevention efforts, this study sought to identify early predictors of PTSD symptoms among adults admitted to a Level I trauma center using a novel an

  2. Operating Analysis of the Closed Supply Chain of Green Agricultural Products Based on Logistics Center

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    This thesis gives the overview of concept and constitution of the closed supply chain of green agricultural products based on logistics center,and the necessity of regarding logistics center as core enterprise.Meanwhile,it analyzes the function of logistics center of agricultural products,namely functions of exchange,collection,distribution,storage and transportation.It also poses the prerequisites of logistics center.The logistics center of agricultural products must have stable profit expectancy,prominent scale,strong appealing power,capacity of bearing market risk and basic thoughts of supply chain management.The functional design of the closed supply chain of green agricultural products has been discussed in 5 aspects,namely logistics center,production base,providers of means of production,retailer and consumer.The operating thoughts of the closed supply chain of green agricultural products based on logistics center are put forward on the basis of the research of operating objective and service target of supply chain as follows:first,based on local principal agricultural products,the logistics center mainly distributes the massed agricultural products;second,it is necessary to choose appropriate strategic cooperative partners to sign contract;third,the operating procedure of supply chain entails bringing in professional managerial talents of supply chain;finally,the relationships of supply chain should be maintained.

  3. Analysis of Bullwhip Effect for Two-level Supply Chain with Multi-distributed Centers

    Institute of Scientific and Technical Information of China (English)

    LirongCui

    2004-01-01

    The bullwhip effect is studied for two-level supply chain with multi-distributed centers. First the model for two-level supply chain with multi-distributed centers is established under some assumptions, then the mathematical description is given for it. Finally a simple example is showed to illustrate the results obtained in the paper.

  4. Analysis of patterns of palliative radiotherapy in north west India: A regional cancer center experience

    Directory of Open Access Journals (Sweden)

    Akhil Kapoor

    2015-01-01

    Full Text Available Background: Palliative radiotherapy (PRT is the eventual requirement in 30-50% of all cancer patients. PRT is primarily aimed to relieve pain and prevent/treat collapse or fracture in case of bone metastasis, to reduce edema in patients with cranial metastasis, and to control distressing symptoms of rapid primary growth. An audit of PRT planned in a busy cancer center can help in the characterization of the requirements of the patients and the formulation of institutional policies. Materials and Methods: In total, 516 patients who received PRT in our regional cancer center from January 2012 to December 2012 and whose complete records were available for analysis were selected for this retrospective study. Medical records and radiotherapy files were analyzed to obtain data such as sociodemographic parameters, prescription of PRT, and follow up. Descriptive statistics were evaluated in terms of frequencies and percentages to allow comparisons. Results: Of the 516 patients, 73% patients were male; the median age of the patients receiving PRT was 62 years (range 13-83 years. About 48% ( n = 248 patients received PRT at the primary site while rest (52% were given PRT at the metastatic site. The most common indication of PRT was pain (56.8% cases, followed by cytostatic PRT (19.8% and raised ICT (12.4%. The median dose prescribed was 30 Gy (range 8-36 Gy delivered in 1-12 fractions over the duration of 1-18 days. The overall response rate was about 43% at 2 weeks of completion of PRT; the median follow-up of the patients was 154 days (range 9-256 days. The long-term symptom relief at median follow up was 8%. Conclusions: Good clinical judgment and expertise is required in prescribing correct fractionation schedule to achieve effective symptom palliation with lowest possible cost and inconvenience to the patients and relatives. Hypofractionated radiotherapy is a feasible treatment option in patients with advanced incurable disease to achieve effective

  5. Managing the Shopping Center Ambience Attributes by Using Importance-Performance Analysis: The Case from Serbia

    Directory of Open Access Journals (Sweden)

    Jelica Marković

    2014-06-01

    Full Text Available This paper examined customers’ perceived importance and performance of shopping center ambience on the examples of the Mercator shopping center and Sad Novi Bazaar shopping center in Novi Sad, Serbia. The shopping center ambience was examined through exterior and interior attributes. It was found that a number of them are very important to customers and their shopping behavior. According to the present research, the most important exterior attributes are: address and location, parking availability, congestion and traffic, exterior display windows and entrances. The most important interior attributes are: cleanliness, temperature, merchandise, lighting, music, scents, absence of tobacco smoke, width of aisles and P.A. usage. The paper also provided information for two studied shopping centers with ambience attributes that performed well or not and everything was presented on the importance-performance grids, which can serve managers as guidelines for further development.

  6. Effectiveness of person-centered care on people with dementia: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Kim SK

    2017-02-01

    Full Text Available Sun Kyung Kim, Myonghwa Park Education and Research Center for Evidence Based Nursing Knowledge, College of Nursing, Chungnam National University, Daejeon, Republic of Korea Background: Person-centered care is a holistic and integrative approach designed to maintain well-being and quality of life for people with dementia, and it includes the elements of care, the individual, the carers, and the family.Aim: A systematic literature review and meta-analysis were undertaken to investigate the effectiveness of person-centered care for people with dementia.Methods: Literature searches were undertaken using six databases including Medline, EMBASE, CINAHL, PsycINFO, Cochrane Database, and KoreaMed using the following keywords: cognition disorder, dementia, person-centered care, patient-centered care, client-centered care, relationship-centered care, and dementia care. The searches were limited to interventional studies written in English and Korean and included randomized controlled studies and noncontrolled studies for people with dementia living in any setting.Results: Nineteen interventional studies, including 3,985 participants, were identified. Of these, 17 studies were from long-term care facilities and two studies were from homecare settings. The pooled data from randomized controlled studies favored person-centered care in reducing agitation, neuropsychiatric symptoms, and depression and improving the quality of life. Subgroup analysis identified greater effectiveness of person-centered care when implemented for people with less severe dementia. For agitation, short-term interventions had a greater effect (standardized mean difference [SMD]: -0.434; 95% conference interval [CI]: -0.701 to -0.166 than long-term interventions (SMD: -0.098; 95% CI: -0.190 to 0.007. Individualized activities resulted in a significantly greater beneficial effect than standard care (SMD: 0.513; 95% CI: -0.994 to -0.032. However, long-term, staff education, and

  7. National Center for Analysis of Energy Systems: program summaries for 1979

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-01

    This Center, founded in January 1976, is one of four areas comprising the Department of Energy and Environment at Brookhaven National Laboratory. The major ongoing activities of the Center concern integrated, quantitative analyses of technological, economic, and environmental aspects of energy at the regional, national, and international levels. The objectives, activities, and sources of support of each of the programs are described and the major accomplishments during the year are outlined. Some of the planned future activities of the Center are indicated, and recent publications are listed.

  8. [Analysis of the transfer of the world medical scientific center until modern times].

    Science.gov (United States)

    Zuo, Han-bin

    2010-03-01

    Since the 16th century, the world medical scientific center has transferred from Italy, Netherlands, the United Kingdom, France and Germany to the United States. The standards by which the above-mentioned countries became the medical scientific center during a certain historical period were not only the number of achievements of the scientific research and the talents, what was more important was their position and function in the leading disciplines. The background of the transfer of the medical scientific center was the economic, cultural and political rise of these countries, and the most important foundation was the innovation of personnel training systems.

  9. A THREE-DIMENSIONAL ANALYSIS OF THE CENTER OF MASS FOR THREE DIFFERENT JUDO THROWING TECHNIQUES

    Directory of Open Access Journals (Sweden)

    Rodney T. Imamura

    2006-07-01

    Full Text Available Four black belt throwers (tori and one black belt faller (uke were filmed and analyzed in three-dimensions using two video cameras (JVC 60 Hz and motion analysis software. Average linear momentum in the anteroposterior (x, vertical (y, and mediolateral (z directions and average resultant impulse of uke's center of mass (COM were investigated for three different throwing techniques; harai-goshi (hip throw, seoi-nage (hand throw, and osoto-gari (leg throw. Each throw was broken down into three main phases; kuzushi (balance breaking, tsukuri (fit-in, and kake (throw. For the harai-goshi and osoto-gari throws, impulse measurements were the largest within kuzushi and tsukuri phases (where collision between tori and uke predominantly occurs. Both throws indicated an importance for tori to create large momentum prior to contact with uke. The seoi-nage throw demonstrated the lowest impulse and maintained forward momentum on the body of uke throughout the entire throw. The harai-goshi and osoto-gari are considered power throws well-suited for large and strong judo players. The seoi-nage throw is considered more technical and is considered well-suited for shorter players with good agility. A form of resistance by uke was found during the kuzushi phase for all throws. The resistance which can be initiated by tori's push or pull allows for the tsukuri phase to occur properly by freezing uke for a good fit-in. Strategies for initiating an effective resistance include initiating movement of uke so that their COM is shifted to their left (for right handed throw by incorporating an instantaneous "snap pull" with the pulling hand during kuzushi to create an opposite movement from uke

  10. ANALYSIS OF FACTORS IMPACTING LAND USE IN TRANSFORMING ISTANBUL HISTORICAL CITY CENTER

    Directory of Open Access Journals (Sweden)

    Ismail Hakan KOLCU

    2015-04-01

    Full Text Available Istanbul historical city center is going through a provincial transformation by quick population increase, multicentered city development, developing tourism and trade feature pressures as well as selection of location for housing. Provincial transformation is briefly described as; an action plan integrating with the city and urban people, prepared to increase life quality based on strategic development plan and within the provincial development vision for the nonfunctional, old and worn provincial pieces unable to fulfill physical, social and economic development dynamics and new requirements. Objective of this study is to find out factors affecting provincial transformation that are observed in research district and positive negative effect ratios based on regression analysis. Research district Sultanahmet and surrounding area located between Divan Yolu Street and Topkapı Palace and Marmara Sea, which is considered among UNESCO Global Heritage Areas, having intensive cultural assets, transforming pursuant to tourism and trade feature pressure, preserving most of its authentic housing texture, worn out as well as observed to be a qualified housing location choice of people with high socio-economic and educational class. It is concluded that the urban transformation resulting from the dynamism in the historical, physical and socioeconomically structure of the space in the research area is weighted with the accommodation and commercial place selections, there are influences of the culture asset structure, some part of the functions being in the place selection and the positive and negative reflections of the quantitative and qualitative characteristics of the focal points on the transformation which is followed on the area and also the land-plot unit price value directs the selections in part.

  11. Combination of Tide Gauge Benchmark Monitoring (TIGA) Analysis Center from repro2 solutions

    Science.gov (United States)

    Hunegnaw, Addisu; Teferle, Felix Norman

    2016-04-01

    Recently the International GNSS Service (IGS) Tide Gauge Benchmark Monitoring (TIGA) Working Group (WG) has completed their repro2 solutions by re-analyzing the full history of all relevant Global Positioning System (GPS) observations from 1995 to 2015. This re-processed data set will provide high-quality estimates of vertical land movements for more than 500 stations, enabling regional and global high-precision geophysical/geodetic studies. All the TIGA Analysis Centres (TACs) have processed the observations recorded by GPS stations at or close to tide gauges, which are available from the TIGA Data Center at the University of La Rochelle (www.sonel.org) besides those of the global IGS core network used for its reference frame implementations. Following the recent improvements in processing models, strategies (http://acc.igs.org/reprocess2.html), this is the first complete re-processing attempt by the TIGA WG to provide homogeneous position time series relevant to sea level changes. In this study we report on a first multi-year daily combined solution from the TIGA Combination Centre (TCC) at the University of Luxembourg (UL) with respect to the latest International Terrestrial Reference Frame (ITRF2014). Using two independent combination software packages, CATREF and GLOBK, we have computed a first daily combined solution from TAC solutions already available to the TIGA WG. These combinations allow an evaluation of any effects from the combination software and of the individual TAC parameters and their influences on the combined solution with respect to the latest ITRF2014. Some results of the UL TIGA multi-year combinations in terms of geocentric sea level changes will be presented and discussed.

  12. Ten years of software sustainability at the Infrared Processing and Analysis Center.

    Science.gov (United States)

    Berriman, G Bruce; Good, John; Deelman, Ewa; Alexov, Anastasia

    2011-08-28

    This paper presents a case study of an approach to sustainable software architecture that has been successfully applied over a period of 10 years to astronomy software services at the NASA Infrared Processing and Analysis Center (IPAC), Caltech (http://www.ipac.caltech.edu). The approach was developed in response to the need to build and maintain the NASA Infrared Science Archive (http://irsa.ipac.caltech.edu), NASA's archive node for infrared astronomy datasets. When the archive opened for business in 1999 serving only two datasets, it was understood that the holdings would grow rapidly in size and diversity, and consequently in the number of queries and volume of data download. It was also understood that platforms and browsers would be modernized, that user interfaces would need to be replaced and that new functionality outside of the scope of the original specifications would be needed. The changes in scientific functionality over time are largely driven by the archive user community, whose interests are represented by a formal user panel. The approach has been extended to support four more major astronomy archives, which today host data from more than 40 missions and projects, to support a complete modernization of a powerful and unique legacy astronomy application for co-adding survey data, and to support deployment of Montage, a powerful image mosaic engine for astronomy. The approach involves using a component-based architecture, designed from the outset to support sustainability, extensibility and portability. Although successful, the approach demands careful assessment of new and emerging technologies before adopting them, and attention to a disciplined approach to software engineering and maintenance. The paper concludes with a list of best practices for software sustainability that are based on 10 years of experience at IPAC.

  13. Analysis of premature births for the period from 2009. to 2013. in Health Center Kosovska Mitrovica

    Directory of Open Access Journals (Sweden)

    Adžić V.

    2015-01-01

    Full Text Available Delivery before 37th week of gestation is defined as preterm, independently of body mass of babies, according to the World Health Organization. Premature birth is the current problem in the world due to the high risk of neonatal morbidity and mortality and incompletely clear etiology. In our country the frequency of preterm delivery is 6%. We have retrospectively analyzed early deliveries in Health Center Kosovska Mitrovica in the period from 2009 to 2013. In this five-year period, there were totaly 3398 deliveries, of which 148 or 4.35 % were preterm delivery. The aim of this study was to investigate the incidence of premature birth in the five-year period in relation to: the total number of births in a given period, the age of the patients, the manner of completion of delivery, gestational week of pregnancy, parity and the most common causes that led to the PTP. In the analysis we have included the body weight and Apgar score of premature infants. We have used protocols of births, maternal history of disease, neonatal protocols and lists of newborns. Most of them were multiparas (41.2 %,56.7 % of pregnant women were aged of 21-30 years and pregnancy in 79.9 % of cases ended with 33 to 37 ng. Vaginal deliveries were completed in 84.4% of premature births, and caesarean in 15.6%. Twin pregnancies with preterm deliveries were represented in 10.2%. The most common weight of premature infants ranged from 2000 to 2500 grams (48.6 %. The most common causes that led to the PTP were PPROM (22.9 %, unknown causes (27. 1 %, multiple pregnancy (18.2 %, genital infection (8.7 %, cervical incompetence (6.7 %, IUGR (5.4%, PIH (4.2%, placental abruption and placenta previa (2.1 % and other (4.7% .

  14. Analysis of 10-Year Training Results of Medical Students Using the Microvascular Research Center Training Program.

    Science.gov (United States)

    Onoda, Satoshi; Kimata, Yoshihiro; Sugiyama, Narushi; Tokuyama, Eijiro; Matsumoto, Kumiko; Ota, Tomoyuki; Thuzar, Moe

    2016-06-01

    Background In this article, we reviewed the training results of medical students using the Microvascular Research Center Training Program (MRCP), and proposed an ideal microsurgical training program for all individuals by analyzing the training results of medical students who did not have any surgical experience. Methods As of 2015, a total of 29 medical students completed the MRCP. In the most recent 12 medical students, the number of trials performed for each training stage and the number of rats needed to complete the training were recorded. Additionally, we measured the operating time upon finishing stage 5 for the recent six medical students after it became a current program. Results The average operating time upon finishing stage 5 for the recent six medical students was 120 minutes ± 11 minutes (standard deviation [SD]). The average vascular anastomosis time (for the artery and vein) was 52 minutes ± 2 minutes (SD). For the most recent 12 medical students, there was a negative correlation between the number of trials performed in the non-rat stages (stages 1-3) and the number of rats used in the rat stages (stages 4-5). Conclusion Analysis of the training results of medical students suggests that performing microsurgery first on silicon tubes and chicken wings saves animals' lives later during the training program. We believe that any person can learn the technique of microsurgery by performing 7 to 8 hours of training per day over a period of 15 days within this program setting.

  15. Transportation Secure Data Center: Real-World Data for Planning, Modeling, and Analysis (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2014-01-01

    This fact sheet describes the Transportation Secure Data Center (TSDC) - an NREL-operated resource that provides secure access to detailed GPS travel data for valuable research purposes in a way that protects original participant privacy.

  16. An Analysis of Student-centered Lesson Planning In English Language Teaching and Learning

    Institute of Scientific and Technical Information of China (English)

    陈荣燕

    2009-01-01

    @@ Chapter I Introduction "Pmpor lesson planning is essential for both novice and experienced tethers"(A course in English language teaching,2000:24).In the lesson planning.teachers determine what techniques,activities and materials will be used in the class beforehand.The question discussed in this essay is that who iS centered in the lesson planning in English language teaching.In the traditional English teaching classroom.teacher is the center of teaching and learning.

  17. Performance Analysis of Heterogeneous Data Centers in Cloud Computing Using a Complex Queuing Model

    Directory of Open Access Journals (Sweden)

    Wei-Hua Bai

    2015-01-01

    Full Text Available Performance evaluation of modern cloud data centers has attracted considerable research attention among both cloud providers and cloud customers. In this paper, we investigate the heterogeneity of modern data centers and the service process used in these heterogeneous data centers. Using queuing theory, we construct a complex queuing model composed of two concatenated queuing systems and present this as an analytical model for evaluating the performance of heterogeneous data centers. Based on this complex queuing model, we analyze the mean response time, the mean waiting time, and other important performance indicators. We also conduct simulation experiments to confirm the validity of the complex queuing model. We further conduct numerical experiments to demonstrate that the traffic intensity (or utilization of each execution server, as well as the configuration of server clusters, in a heterogeneous data center will impact the performance of the system. Our results indicate that our analytical model is effective in accurately estimating the performance of the heterogeneous data center.

  18. Maturity analysis method of storage process in distribution centers from Fortaleza-CE’s supermarkets: a multicase study

    Directory of Open Access Journals (Sweden)

    Piter Anderson Severino de Jesus

    2014-12-01

    Full Text Available Logistics and processes, especially storage, are presented as one of the ways the company has to reduce costs and add value to stakeholders. This article aims to develop a method for analyzing maturity to evaluate the storage process at Distribution Centers (DC in Fortaleza / CE. Maturity is defined as how involved the DC is in a particular area or process. Through this analysis, the distribution center can leverage strengths and resolve or mitigate weaknesses. To this end, attributes, dimensions and practices for infrastructure organization, people and technology, as well as internal and external interfaces were established. The instrument was also developed for diagnosing the DC. For elaborating the method, library research and validation were performed with professional logistics. The tool was applied to distribution centers and the heterogeneity of the maturity of Fortaleza DCs was observed.

  19. Situation analysis of trauma based on Arizona trauma center standards in university hospitals of Tehran, Iran

    Institute of Scientific and Technical Information of China (English)

    Mahdi Sharif-Alhoseini; Aliashraf Eghbali; Vafa Rahimi-Movaghar; Soheil Saadat

    2009-01-01

    Objective: Injuries are common and important problem in Tehran, capital of Iran. Although therapeutic centers are not essentially established following the constructional principles of developed countries, the present opportunities and equipments have to be used properly. We should recognize and reduce the deficits based on the global standards.This study deliberates the trauma resources and capacities in university hospitals of Tehran based on Arizona trauma center standards, which are suitable for the assessment of trauma centers.Methods: Forty-one university hospitals in Tehran were evaluated for their conformity with "Arizona trauma center standards" in 2008. A structured interview was arranged with the "Educational Supervisor" of all hospitals regarding their institutional organization, departments, clini-cal capabilities, clinical qualifications, facilities and resources, rehabilitation services, performance improvement, continuing education, prevention, research and additional requirements for pediatric trauma patients. Relative frequencies and percentages were calculated and Student's t test was used to compare the mean values.Results: Forty-one hospitals had the average of 77.7 (50.7%) standards from 153 Arizona trauma center standards and these standards were present in 97.5 out of 153 (63.7%) in 17 general hospitals. Based on the subgroups of the standards, 64.8% items of hospital resources and capabilities were considered as a subgroup with the maximum criteria, and 17.7% items of research section as another subgroup with the minimum standards.Conclusions: On the basis of our findings, no hospital meet all the Arizona trauma center standards completely. The hospitals as trauma centers at different levels must be promoted to manage trauma patients desirably.

  20. A cross-case analysis of three Native Science Field Centers

    Science.gov (United States)

    Augare, Helen J.; Davíd-Chavez, Dominique M.; Groenke, Frederick I.; Little Plume-Weatherwax, Melissa; Lone Fight, Lisa; Meier, Gene; Quiver-Gaddie, Helene; Returns From Scout, Elvin; Sachatello-Sawyer, Bonnie; St. Pierre, Nate; Valdez, Shelly; Wippert, Rachel

    2015-12-01

    Native Science Field Centers (NSFCs) were created to engage youth and adults in environmental science activities through the integration of traditional Native ways of knowing (understanding about the natural world based on centuries of observation including philosophy, worldview, cosmology, and belief systems of Indigenous peoples), Native languages, and Western science concepts. This paper focuses on the Blackfeet Native Science Field Center, the Lakota Native Science Field Center, and the Wind River Native Science Field Center. One of the long-term, overarching goals of these NSFCs was to stimulate the interest of Native American students in ways that encouraged them to pursue academic and career paths in science, technology, engineering, and mathematics (STEM) fields. A great deal can be learned from the experiences of the NSFCs in terms of effective educational strategies, as well as advantages and challenges in blending Native ways of knowing and Western scientific knowledge in an informal science education setting. Hopa Mountain—a Bozeman, Montana-based nonprofit—partnered with the Blackfeet Community College on the Blackfeet Reservation, Fremont County School District #21 on the Wind River Reservation, and Oglala Lakota College on the Pine Ridge Reservation to cooperatively establish the Native Science Field Centers. This paper presents a profile of each NSFC and highlights their program components and accomplishments.

  1. [Severe neonatal acidosis: comparison and analysis of obstetrical practices in two French perinatal centers].

    Science.gov (United States)

    Pommereau-Lathelize, J; Maisonneuve, E; Jousse, M; Guilbaud, L; Carbonne, B; Pierre, F

    2014-04-01

    To identify and compare risk factors for severe neonatal acidosis, defined by an umbilical artery pH inferior to 7.00, and clinical practices in two different perinatal centers. In a retrospective study, from 2003 to 2008, in two university perinatal centers (Poitiers and Saint-Antoine in Paris) on all term pregnancies complicated by severe neonatal acidosis (umbilical artery pHacidosis. The rate was similar for both perinatal centers of Poitiers and Saint-Antoine (0.92% and 0.77% respectively). Factors associated with severe neonatal acidosis were similar in both centers: maternal age, thick meconium, prior cesarean section. There were differences in obstetrical practices between the two centers: there were more caesarean sections and assisted vaginal deliveries in Paris and more inductions of labour in Poitiers. Severe neonatal acidosis is associated with the geographical origin, the progress of labour and the mode of delivery. It seems that severe neonatal acidosis is unrelated to cesarean delivery. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  2. A cross-case analysis of three Native Science Field Centers

    Science.gov (United States)

    Augare, Helen J.; Davíd-Chavez, Dominique M.; Groenke, Frederick I.; Little Plume-Weatherwax, Melissa; Lone Fight, Lisa; Meier, Gene; Quiver-Gaddie, Helene; Returns From Scout, Elvin; Sachatello-Sawyer, Bonnie; St. Pierre, Nate; Valdez, Shelly; Wippert, Rachel

    2017-06-01

    Native Science Field Centers (NSFCs) were created to engage youth and adults in environmental science activities through the integration of traditional Native ways of knowing (understanding about the natural world based on centuries of observation including philosophy, worldview, cosmology, and belief systems of Indigenous peoples), Native languages, and Western science concepts. This paper focuses on the Blackfeet Native Science Field Center, the Lakota Native Science Field Center, and the Wind River Native Science Field Center. One of the long-term, overarching goals of these NSFCs was to stimulate the interest of Native American students in ways that encouraged them to pursue academic and career paths in science, technology, engineering, and mathematics (STEM) fields. A great deal can be learned from the experiences of the NSFCs in terms of effective educational strategies, as well as advantages and challenges in blending Native ways of knowing and Western scientific knowledge in an informal science education setting. Hopa Mountain—a Bozeman, Montana-based nonprofit—partnered with the Blackfeet Community College on the Blackfeet Reservation, Fremont County School District #21 on the Wind River Reservation, and Oglala Lakota College on the Pine Ridge Reservation to cooperatively establish the Native Science Field Centers. This paper presents a profile of each NSFC and highlights their program components and accomplishments.

  3. Analysis of Difference in Center-of-Pressure Positions Between Experts and Novices During Asymmetric Lifting

    Science.gov (United States)

    Yamada, Kenji; Kido, Michiko; Okada, Shima; Nomura, Taishin; Ohno, Yuko

    2016-01-01

    Although numerous studies have analyzed the relationship between manual material handling (MMH) and the forces acting on the lumbar spine, the difference in the MMH between experts and novices through the analysis of measured data has not been well studied. The purpose of this paper was to analyze the difference in the MMH positions between ten skilled experts working at a freight transport company (Group 1) and five unskilled novices without any experience (Group 2) during asymmetric lifting. All the human subjects performed asymmetric lifting experiments with closed eyes; the experiments involved moving loads (6 and 18 kg) to the left side. Time series data of the vertical ground reaction force were measured, using a Wii Balance Board, and then, the center-of-pressure (CoP) trajectories were calculated. The balance board was used for the measurement, because it was reliable, inexpensive, and portable and provided good repeatability even on rough surfaces, and all the information pertaining to the load and worker under various conditions was captured without any omissions. Under the 18 kg load condition, the CoP positions for Group 2 were located on the same side during left asymmetric lifting; however, those for Group 1 were located on the opposite side during left asymmetric lifting (\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$P measurement results, we inferred that the difference in the CoP positions between the two different groups could be attributed to the difference in the hip positions. Most skilled experts position their hips in such a way that their CoP trajectories move toward the opposite side during left asymmetric lifting. Although the skillful characteristics of experts may be responsible for the lightening of the burden on the waist during asymmetric

  4. An analysis of paramilitary referrals to psychiatric services at a tertiary care center

    Directory of Open Access Journals (Sweden)

    Rohit Verma

    2013-01-01

    Full Text Available Background: There is a dearth of specialized mental health services for Indian paramilitary service personnel. Those requiring psychiatric evaluation are referred to government psychiatric services often with minimal information. Hence, major diagnostic and decision making relies on the psychiatrist′s clinical evaluation and judgment. The aim of the present study was to quantitatively evaluate the paramilitary referrals to psychiatric services at a tertiary care referral center. Materials and Methods: A retrospective chart analysis of all consecutive referrals by various Indian paramilitary services to a tertiary care hospital (2008-2010 was carried out. Results: Among the sample of 18 referrals, all were males (mean age: 37 years ± standard deviation (SD =7.79. Various reasons for referral included: Evaluation of fitness for duty (83.3%, fitness to handle firearms (16.7%, and for disability certification (5.6%. There were no informants at all in 22.2%, and family members were available in only 11.1%. Hence, most referrals were admitted to the psychiatry ward for observation for various lengths of time. The mean duration of assessment (outpatient and inpatient was 17.89 days (SD = 20.74 and final reported diagnoses were schizophrenia, depression, and bipolar disorder in 16.7, 11.1, and 11.1%, respectively. There was concurrent history of alcohol and nicotine dependence (40%. A large group (40% was diagnosed not to suffer from a major mental illness, while a firm and final diagnosis could not be arrived at in 16.7% subjects. Only one subject was given the fitness to handle firearms, fitness for duty was refused in three (16.7% subjects, and one subject was referred to neurology after being diagnosed as a case of seizure disorder. Conclusion: There is an urgent need for intensive training both to paramilitary physicians as well as to general hospital psychiatrists regarding proper assessment of paramilitary personnel, as there are frequent

  5. ANALYSIS OF PROPERTY STRUCTURE OF MEDICAL DIAGNOSTIC CONSULTATIVE CENTERS IN VARNA

    Directory of Open Access Journals (Sweden)

    Lyubomira Koeva-Dimitrova

    2016-06-01

    Full Text Available The production and financial performance of one company depend on the size of its assets and the aptness of the assets� proportion. The aim of this article is urged to make an external analysis of the asset structure of medical diagnostic and consultative centers (DCC in Varna and on this basis to draw conclusions regarding their property structure. Subject of the study is the annual financial statements, published in the Commercial Register, of all 9 in number DCCs that are registered in Varna. The names of DCC's are encoded with numbers from 1 to 9, with numbers from 1 to 7 are 6 DCCs, owned by the Municipality of Varna, one of them is a subsidiary of staterun hospital, with number 8 and 9 are private DCC's. Subject of the study are the assets and their proportion in the studied hospitals. The study covers 7 years - from year 2008 to year 2014. In the study are calculated and compared the indicators for intensity of the property as well as the relative share of the fixed assets obtained as an average value of the relative shares of all nine in number hospitals for the entire studied period. The following important conclusions have been made: 1 The average relative share of fixed assets of Varna DCCs for the period 2008 � 2014 is 56.85%. 2 The proportion of FA calculated only for municipal DCC's (average value is significantly higher - 72.75% compared to the overall average of 56.85%. 3 Private hospitals invest a lot less money in fixed assets than the municipal ones. 4 Since 2013 there is a slight increase of FA share in the private and the state-run DCC, and a slight decrease in the municipal ones (71.93. 5 The creation of an online database comprising of average indicators of the financial and property status of Bulgarian companies is essential and necessary condition for improving their competitiveness by providing reliable, accurate and usable information for comparison.

  6. Analysis of XXI Century Disasters in the National Geophysical Data Center Historical Natural Hazard Event Databases

    Science.gov (United States)

    Dunbar, P. K.; McCullough, H. L.

    2011-12-01

    The National Geophysical Data Center (NGDC) maintains a global historical event database of tsunamis, significant earthquakes, and significant volcanic eruptions. The database includes all tsunami events, regardless of intensity, as well as earthquakes and volcanic eruptions that caused fatalities, moderate damage, or generated a tsunami. Event date, time, location, magnitude of the phenomenon, and socio-economic information are included in the database. Analysis of the NGDC event database reveals that the 21st century began with earthquakes in Gujarat, India (magnitude 7.7, 2001) and Bam, Iran (magnitude 6.6, 2003) that killed over 20,000 and 31,000 people, respectively. These numbers were dwarfed by the numbers of earthquake deaths in Pakistan (magnitude 7.6, 2005-86,000 deaths), Wenchuan, China (magnitude 7.9, 2008-87,652 deaths), and Haiti (magnitude 7.0, 2010-222,000 deaths). The Haiti event also ranks among the top ten most fatal earthquakes. The 21st century has observed the most fatal tsunami in recorded history-the 2004 magnitude 9.1 Sumatra earthquake and tsunami that caused over 227,000 deaths and 10 billion damage in 14 countries. Six years later, the 2011 Tohoku, Japan earthquake and tsunami, although not the most fatal (15,000 deaths and 5,000 missing), could cost Japan's government in excess of 300 billion-the most expensive tsunami in history. Volcanic eruptions can cause disruptions and economic impact to the airline industry, but due to their remote locations, fatalities and direct economic effects are uncommon. Despite this fact, the second most expensive eruption in recorded history occurred in the 21st century-the 2010 Merapi, Indonesia volcanic eruption that resulted in 324 deaths, 427 injuries, and $600 million in damage. NGDC integrates all natural hazard event datasets into one search interface. Users can find fatal tsunamis generated by earthquakes or volcanic eruptions. The user can then link to information about the related runup

  7. Analysis and Assessment of Peak Lightning Current Probabilities at the NASA Kennedy Space Center

    Science.gov (United States)

    Johnson, D. L.; Vaughan, W. W.

    1999-01-01

    This technical memorandum presents a summary by the Electromagnetics and Aerospace Environments Branch at the Marshall Space Flight Center of lightning characteristics and lightning criteria for the protection of aerospace vehicles. Probability estimates are included for certain lightning strikes (peak currents of 200, 100, and 50 kA) applicable to the National Aeronautics and Space Administration Space Shuttle at the Kennedy Space Center, Florida, during rollout, on-pad, and boost/launch phases. Results of an extensive literature search to compile information on this subject are presented in order to answer key questions posed by the Space Shuttle Program Office at the Johnson Space Center concerning peak lightning current probabilities if a vehicle is hit by a lightning cloud-to-ground stroke. Vehicle-triggered lightning probability estimates for the aforementioned peak currents are still being worked. Section 4.5, however, does provide some insight on estimating these same peaks.

  8. Mental health resources for LGBT collegians: a content analysis of college counseling center Web sites.

    Science.gov (United States)

    Wright, Paul J; McKinley, Christopher J

    2011-01-01

    This study content analyzed a randomly selected stratified national sample of 203 four-year United States colleges' counseling center Web sites to assess the degree to which such sites feature information and reference services for lesbian, gay, bisexual, and transgender (LGBT) collegians. Results revealed that LGBT-targeted communications were infrequent. For instance, fewer than one third of counseling center Web sites described individual counseling opportunities for LGBT students, fewer than 11% mentioned group counseling opportunities, and fewer than 6% offered a university crafted pamphlet with information about LGBT issues and resources. Findings are interpreted within the context of prior LGBT student health research.

  9. Assessing students' genre knowledge in an engineering writing center: An analysis of sophomore lab reports in electrical and computer engineering

    Science.gov (United States)

    Walker, Kristin Wilds Davidson

    As discipline-specific writing centers continue to increase in number, writing center consultants must determine ways to help their clients acquire discipline-specific and course-specific literacy. One way to achieve this goal is through genre analysis. This study focuses on the genre of EECE 201 (Tools and Techniques for Electrical and Computer Engineers) lab reports and strategies writing center consultants can implement to teach students communication skills necessary for discipline-specific literacy. Beginning with a discussion of the Electrical and Computer Engineering (ECE) Writing Center's history, the methodological foundations of this study, and an historical overview of genre theory from classical times to the present, this study surveys the history and debates surrounding teaching genres to students. The role of assessment in analyzing and teaching genre is discussed as well, with application specifically to the sophomore-level EECE 201 course within ECE at the University of South Carolina. The study itself consists of analyzing four students' lab reports written for the EECE 201 course. Using a list of eleven characteristics developed with experienced communicators within this discipline, I analyzed each report (there is a total of 14), determining to what extent the characteristics appeared in the reports. At the end of each student's analysis, a table summarizes the information gathered from the reports, and overall conclusions are drawn for each student. The end of the study chapter presents generic writing trends exhibited by the students during the semester, such as inability to show evidence of inductive/deductive reasoning and difficulties with conceptualizing audience and applying formatting skills. The study concludes by recommending strategies that ECE Writing Center consultants can implement to help the sophomore students acquire discipline-specific knowledge. Going beyond the ECE Writing Center's context, however, the study also suggests

  10. A Statistical Analysis of Point-like Sources in the Chandra Galactic Center Survey

    Institute of Scientific and Technical Information of China (English)

    J.F.Wu; S.N.Zhang; F.J.Lu; Y.K.Jin

    2007-01-01

    The Chandra Galactic Center Survey detected ~ 800 X-ray point-like sources in the 2°× 0.8° sky region around the Galactic Center. We study the spatial and luminosity distributions of these sources according to their spectral properties. Fourteen bright sources detected are used to fit jointly an absorbed power-law model, from which the power-law photon index is determined to be ~2.5. Assuming that all other sources have the same power-law form, the relation between hardness ratio and HI column density NH is used to estimate the NH values for all sources. Monte Carlo simulations show that these sources are more likely concentrated in the Galactic center region, rather than distributed throughout the Galactic disk. We also find that the luminosities of the sources are positively correlated with their HI column densities, i.e., a more luminous source has a higher HI column density. From this relation, we suggest that the X-ray luminosity comes from the interaction between an isolated old neutron star and interstellar medium (mainly dense molecular clouds). Using the standard Bondi accretion theory and the statistical information of molecular clouds in the Galactic center, we confirm this positive correlation and calculate the luminosity range in this scenario,which is consistent with the observation (1032 - 1035 erg s-1).

  11. Engaged managers are not workaholics: Evidence from a longitudinal person-centered analysis

    NARCIS (Netherlands)

    Mäkikangas, A.; Schaufeli, W.B.; Tolvanen, A.; Feldt, T.

    2013-01-01

    The aims of this two-year follow-up study among Finnish managers (n = 463) were twofold: first, to investigate the relation between work engagement and workaholism by utilizing both variable- and person-centered approaches and second, to explore whether and how experiences of work engagement and wor

  12. Ecology-Centered Experiences among Children and Adolescents: A Qualitative and Quantitative Analysis

    Science.gov (United States)

    Orton, Judy

    2013-01-01

    The present research involved two studies that considered "ecology-centered experiences" (i.e., experiences with living things) as a factor in children's environmental attitudes and behaviors and adolescents' ecological understanding. The first study (Study 1) examined how a community garden provides children in an urban setting the…

  13. Ecology-Centered Experiences among Children and Adolescents: A Qualitative and Quantitative Analysis

    Science.gov (United States)

    Orton, Judy

    2013-01-01

    The present research involved two studies that considered "ecology-centered experiences" (i.e., experiences with living things) as a factor in children's environmental attitudes and behaviors and adolescents' ecological understanding. The first study (Study 1) examined how a community garden provides children in an urban setting the…

  14. Comparative Analysis of Fusion Center Outreach to Fire and EMS Agencies

    Science.gov (United States)

    2015-12-01

    Shooter” Response Strategies,” Homeland Security Affairs 10 (February 2014), article 3, https://www.hsaj.org/articles/253. xvi each fusion center has...consisting of the counties of: Los Angeles, Orange, Riverside, San Bernardino, San Luis Obispo, Santa Barbara, and Ventura along with all the cities

  15. User-Centered Perspective of Information Retrieval Research and Analysis Methods.

    Science.gov (United States)

    Sugar, William

    1995-01-01

    Reviews information retrieval (IR) studies since 1986 from the user's perspective. Identifies two main approaches that advocate user-centered design theory: (1) the cognitive approach; and (2) the holistic approach. Also explores other approaches--systems thinking/action research and usability techniques that may have potential for IR research and…

  16. User-Centered Design Guidelines for Collaborative Software for Intelligence Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Scholtz, Jean; Endert, Alexander N.

    2014-08-01

    In this position paper we discuss the necessity of using User-Centered Design (UCD) methods in order to design collaborative software for the intelligence community. We present some standing issues in collaborative software based on existing work within the intelligence community. Based on this information we present opportunities to address some of these challenges.

  17. User-Centered Design Guidelines for Collaborative Software for Intelligence Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Scholtz, Jean; Endert, Alexander

    2014-07-01

    In this position paper we discuss the necessity of using User-Centered Design (UCD) methods in order to design collaborative software for the intelligence community. We discuss a number of studies of collaboration in the intelligence community and use this information to provide some guidelines for collaboration software.

  18. Analysis of the Cost of Training Residents in a Community Health Center.

    Science.gov (United States)

    Jones, Timothy F.; And Others

    1995-01-01

    The costs of outpatient training for medical residents in a community health center (CHC) are analyzed, based on a family practice residency of one medical school. The model used a computer spreadsheet program to determine the financial impact of the program on the CHC. Sensitivity analyses determined the effects of changing productivity, nursing…

  19. A Comparative Analysis of MEXT English Reading Textbooks and Japan's National Center Test

    Science.gov (United States)

    Underwood, Paul

    2010-01-01

    Despite the influence of changing demographics in Japan, the National Center Test for University Entrance Exams continues to assert an ever increasing role in the process of university admissions. In preparation for this examination, the majority of senior high school students learn from textbooks approved by the Japanese Ministry of Education,…

  20. Transportation Secure Data Center: Real-world Data for Planning, Modeling, and Analysis (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2015-01-01

    The Transportation Secure Data Center (TSDC) at www.nrel.gov/tsdc provides free, web-based access to detailed transportation data from a variety of travel surveys conducted across the nation. While preserving the privacy of survey participants, this online repository makes vital transportation data broadly available to users from the comfort of their own desks via a secure online connection.

  1. Primary Care Screening of Depression and Treatment Engagement in a University Health Center: A Retrospective Analysis

    Science.gov (United States)

    Klein, Michael C.; Ciotoli, Carlo; Chung, Henry

    2011-01-01

    Objectives: This retrospective study analyzed a primary care depression screening initiative in a large urban university health center. Depression detection, treatment status, and engagement data are presented. Participants: Participants were 3,713 graduate and undergraduate students who presented consecutively for primary care services between…

  2. Primary Care Screening of Depression and Treatment Engagement in a University Health Center: A Retrospective Analysis

    Science.gov (United States)

    Klein, Michael C.; Ciotoli, Carlo; Chung, Henry

    2011-01-01

    Objectives: This retrospective study analyzed a primary care depression screening initiative in a large urban university health center. Depression detection, treatment status, and engagement data are presented. Participants: Participants were 3,713 graduate and undergraduate students who presented consecutively for primary care services between…

  3. ANALYSIS OF THE RESULTS IN IMPLEMENTING THE OPERATIONAL PROGRAM FOR HUMAN RESOURCES DEVELOPMENT 2007-2013 FOR CENTER REGION, ROMANIA

    OpenAIRE

    Ionela Gavrila-Paven; Iulian Bogdan Dobra; Lucian Docea

    2013-01-01

    This study aims to highlight the results achieved through the implementation ofprojects financed by the European Social Fund through the Operational Program for HumanResources Development 2007-2013 at regional level. It was considered Center Region for thepresentation and analysis of data from the point of view of absorption and especially from the pointof view of the results obtained by analyzing outcome indicators reported by the recipients for 2007-2012. Although the degree of absorption i...

  4. ADEQUACY OF STRATEGIC HEALTH HEALTH CENTER IN INDONESIA (Analysis of Implementation Permenkes 75 /2014

    Directory of Open Access Journals (Sweden)

    Didik Budijanto

    2015-11-01

    Full Text Available Background: Subjected to five of the National Medium Term Development Plan (RPJMN, the requirement for health personnel, drugs and vaccines In order to meet the needs of health workers, the health minister of Health issued Decree number 75 of 2014. The purpose of this paper is to determine the adequacy of health workers in health centers located in Indonesia. Methods: Data source of PPSDM and Media Centre of the Ministry of Health. Data up to the end of December 2013. The determination of the adequacy of strategic health workers referring health centers Permenkes No. 75 in 2014. At least four types of health personnel that must exist in health centers, namely doctors, dentists, nurses and midwives. Criteria for assessment of the adequacy of four types of health workers in health centers, namely: less, Pretty and Overload. Results: The condition of the health center there is a shortage of general practitioners in five provinces, namely West Papua (77.3%, Papua (55.9%, Southeast Sulawesi (47.5%, East Nusa Tenggara (46.7% and Nusa Tenggara Barat (41.4%. PHC is a shortage of midwives in the province among others in DKI Jakarta (86.2%, West Papua (71.6%, Papua (70.8%, Maluku (58.6% and East Kalimantan (51,4%. Conclusion:The placement of strategic health workers have not referring Permenkes number 75 in 2014. Recommendation: socialization Permenkes number 75 of 2014 must be implemented immediately, in order to plan the placement of health personnel refers to the Permenkes

  5. Bibliometric analysis of poison center-related research published in peer-review journals.

    Science.gov (United States)

    Forrester, M B

    2016-07-01

    Poison centers advance knowledge in the field of toxicology through publication in peer-review journals. This investigation describes the pattern of poison center-related publications. Cases were poison center-related research published in peer-review journals during 1995-2014. These were identified through searching the PubMed database, reviewing the tables of contents of selected toxicology journals, and reviewing abstracts of various national and international meetings. The following variables for each publication were identified: year of publication, journal, type of publication (meeting abstract vs. other, i.e. full article or letter to the editor), and the country(ies) of the poison center(s) included in the research. Of the 3147 total publications, 62.1% were meeting abstracts. There were 263 publications in 1995-1999, 536 in 2000-2004, 999 in 2005-2009, and 1349 in 2010-2014. The publications were in 234 different journals. The journals in which the highest number of research was published were Clinical Toxicology (69.7%), Journal of Medical Toxicology (2.2%), and Veterinary and Human Toxicology (2.1%). The research was reported from 62 different countries. The countries with the highest number of publications were the United States (67.9%), United Kingdom (6.5%), Germany (3.9%), France (2.5%), and Italy (2.4%). The number of publications increased greatly over the 20 years. Although the publications were in a large number of journals, a high proportion of the publications were in one journal. While the research came from a large number of countries, the preponderance came from the United States.

  6. Using conjoint analysis to model the preferences of different patient segments for attributes of patient-centered care.

    Science.gov (United States)

    Cunningham, Charles E; Deal, Ken; Rimas, Heather; Campbell, Heather; Russell, Ann; Henderson, Jennifer; Matheson, Anne; Melnick, Blake

    2008-12-01

    A consensus regarding the components of a patient-centered approach to healthcare does not exist. Although patient-centered care should be predicated on patient preferences, existing models provide little evidence regarding the relative importance of different care processes to patients themselves. To involve patients in the design of a model of patient-centered care for a corporation of Canadian teaching hospitals. Using themes from focus groups and interviews, a conjoint survey was developed comprising 14 four-level patient-centered care attributes. Sawtooth Software's Choice Based Conjoint module (version 2.6.7) was used to design the survey. Each participant completed 15 choice tasks, each task presenting a choice between three hospitals described by a different combination of patient-centered care attribute levels. Latent class analysis was used to identify segments of participants with similar patient-centered care choice patterns. Randomized First Choice simulations were used to predict the percentage of participants in each segment who would choose different approaches to improving patient-centered care.Representative hospital service users were recruited from a corporation of five Canadian teaching hospitals serving a regional population of 2.2 million. A total of 508 patients and family members of children completed a choice-based conjoint survey. Latent class analysis revealed two segments: an informed care segment and a convenient care segment. Participants in the informed care segment (71.3% of the sample) were more likely to have higher education, be non-immigrants, speak English as a first language, and be outpatients or family members.The information needed to understand health concerns, an opportunity to learn health improvement skills, teams that communicated effectively, short waiting times, and collaborative treatment planning were more important to the informed care segment than to the convenient care segment. Convenient settings, a welcoming

  7. Eligibility Comparison of Beach Tourism and Non-Beach Tourism Health Centers in Bali Province (Secundery Analysis of Rifaskes 2011

    Directory of Open Access Journals (Sweden)

    Suharmiati Suharmiati

    2015-03-01

    Province of Bali service tourists. It should be the responsibility of the government. On the other hand the feasibility of health centers (HC based on the availability of coastal tourism facilities and infrastructure, including human resources available to the health service is not clear. This study compared the feasibility of health centers shore excursions and non touristic beach health centers in Bali Province. Methods:Secondary data Healthcare Research Facility (Rifaskes 2011 all health centers in the Province of Bali. The number of samples are 114 health centers. Variabels consisted of facilities, infrastructure, human resources and health programs. The analysis is done by giving the value (weight of each variabel, then performed the scoring of each variabel both in Beach Tourist and Non Tourist Health Centers. Distribution of of the multiplication of the value with a score used to determine the feasibility of each variabel by calculating the mean (x and standart deviation (SD. Comparison of eligibility of Health Centers by differentiating the mean (x of each health center using different test (t test. Result: There is no difference in viability between Tourist and Non Tourist Beach the shore excursions based on the availability of facilities, infrastructure, human resources and health services (p > 0.05. Recomendation: Suggested health centers increase the completeness and appropriate management to be a Health Centers for Tourist, and cooperation with private clinics, the has to monitor the services and the due to cases HC responsibility.Key words: feasibility, Tourist Health Centers, Health Centers Non Tourist, Bali Province

  8. Efficiency measurement of Swiss shopping centers using Data Envelopment Analysis (DEA)

    OpenAIRE

    Alexandra Bay

    2015-01-01

    DEA as an Operations Research based linear programming approach for evaluating the relative performance of homogenous Decision Making Units (DMUs) is applied to Swiss shopping centers. Output-to-input efficiency ratios – as for example the sales productivity – incorporate one output (sales) and one input (sales area). Peer group comparisons (efficiency rankings) are difficult if multiple inputs and / or multiple outputs of different kind of data (quantitative, qualitative, categorical etc.) o...

  9. The Cost analysis of cervical cancer screening services provided by Damavand health center in 2013

    Directory of Open Access Journals (Sweden)

    Arezoo Chouhdari

    2015-03-01

    Full Text Available Background: Today, the health sector in many countries is facing with severe resource constraints; hence it is absolutely necessary that cost-benefit and cost-effectiveness assessment have a major role in design of health services. The purpose of this study was to evaluate the cost-benefit and effectiveness of cervical cancer screening service (Pap smear test done by the health centers in Damavand County in 2013.  Methods: This is a descriptive study with cross-sectional method. All data was extracted from existing documents in Damavand health network.Cost of service screening for doing Pap smear test (manpower costs of performing the service, the cost of transferring samples, water, electricity, telephone and gas was estimated in all health centers then results, were compared with the incomes of this service.  Results: Screening program coverage was 22.3%, 6.9% and 6.05% in 2011, 2012 and 2013 respectively. All costs and incomes of units performing Pap smear screening test were calculated. Entire costs and incomes of this service during 2013 were respectively 303,009,000 and 11,640,000 RLS equal $12,227 and $496.73. Therefore, the cost-benefit ratio of this screening test was approximately 0.040.  Conclusion: The costs of units performing cervical cancer screening test in Damavand Health Center were much more than this benefit and because of a none-positive Pap smear test in spite of high cost, performing this test in Damavand health centers was not cost effective.

  10. The Cost analysis of cervical cancer screening services provided by Damavand health center in 2013

    Directory of Open Access Journals (Sweden)

    Arezoo Chouhdari

    2015-03-01

    Full Text Available Background: Today, the health sector in many countries is facing with severe resource constraints; hence it is absolutely necessary that cost-benefit and cost-effectiveness assessment have a major role in design of health services. The purpose of this study was to evaluate the cost-benefit and effectiveness of cervical cancer screening service (Pap smear test done by the health centers in Damavand County in 2013.  Methods: This is a descriptive study with cross-sectional method. All data was extracted from existing documents in Damavand health network.Cost of service screening for doing Pap smear test (manpower costs of performing the service, the cost of transferring samples, water, electricity, telephone and gas was estimated in all health centers then results, were compared with the incomes of this service.  Results: Screening program coverage was 22.3%, 6.9% and 6.05% in 2011, 2012 and 2013 respectively. All costs and incomes of units performing Pap smear screening test were calculated. Entire costs and incomes of this service during 2013 were respectively 303,009,000 and 11,640,000 RLS equal $12,227 and $496.73. Therefore, the cost-benefit ratio of this screening test was approximately 0.040.  Conclusion: The costs of units performing cervical cancer screening test in Damavand Health Center were much more than this benefit and because of a none-positive Pap smear test in spite of high cost, performing this test in Damavand health centers was not cost effective.

  11. Nuclear Energy Center study. Phase II. Site suitability analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Fellows, W.S.; Sharp, J.M.; Benator, B.I.

    1978-06-01

    A site screening study was conducted to identify a site or sites for detailed, site-specific study as a nuclear energy center. Using technical criteria of water requirements, geotechnical constraints, and projected load center and transmission considerations as well as environmental and institutional considerations, five potential study sites in the State of South Carolina were identified, evaluated against established criteria, and ranked according to their acceptability as potential nuclear energy center study sites. Consideration of what is ''representative'' of a site as well as the ranking score was factored into site recommendations, since the site deemed easiest to license and permit may not be the most desirable site for future study of the technical and institutional feasibility and practicality of a specific site. The sites near Lake Hartwell and the Savannah River Plant (SRP) of the Department of Energy were selected as potential study sites after consideration of the above criteria. Because the Lake Hartwell site offers the opportunity to consider institutional issues which may be more representative of other possible NEC sites, it is recommended that the Lake Hartwell site be studied to establish the feasibility and practicality of the nuclear energy concept on a site-specific basis.

  12. Principal component analysis in ground reaction forces and center of pressure gait waveforms of people with transfemoral amputation.

    Science.gov (United States)

    Soares, Denise Paschoal; de Castro, Marcelo Peduzzi; Mendes, Emilia Assunção; Machado, Leandro

    2016-12-01

    The alterations in gait pattern of people with transfemoral amputation leave them more susceptible to musculoskeletal injury. Principal component analysis is a method that reduces the amount of gait data and allows analyzing the entire waveform. To use the principal component analysis to compare the ground reaction force and center of pressure displacement waveforms obtained during gait between able-bodied subjects and both limbs of individuals with transfemoral amputation. This is a transversal study with a convenience sample. We used a force plate and pressure plate to record the anterior-posterior, medial-lateral and vertical ground reaction force, and anterior-posterior and medial-lateral center of pressure positions of 12 participants with transfemoral amputation and 20 able-bodied subjects during gait. The principal component analysis was performed to compare the gait waveforms between the participants with transfemoral amputation and the able-bodied individuals. The principal component analysis model explained between 74% and 93% of the data variance. In all ground reaction force and center of pressure waveforms relevant portions were identified; and always at least one principal component presented scores statistically different (p amputation compared to the able-bodied participants. Principal component analysis reduced the amount of data, allowed analyzing the whole waveform, and identified specific sub-phases of gait that were different between the groups. Therefore, this approach seems to be a powerful tool to be used in gait evaluation and following the rehabilitation status of people with transfemoral amputation. © The International Society for Prosthetics and Orthotics 2015.

  13. Ayahuasca Exposure: Descriptive Analysis of Calls to US Poison Control Centers from 2005 to 2015.

    Science.gov (United States)

    Heise, C William; Brooks, Daniel E

    2016-11-28

    Ayahuasca is a hallucinogenic plant preparation which usually contains the vine Banisteriopsis caapi and the shrub Psychotria viridis. This tea originates from the Amazon Basin where it is used in religious ceremonies. Because interest in these religious groups spreading as well as awareness of use of ayahuasca for therapeutic and recreational purposes, its use is increasing. Banisteriopsis caapi is rich in β-carbolines, especially harmine, tetrahydroharmine and harmaline, which have monoamine oxidase inhibiting (MAOI) activity. Psychotria viridis contains the 5HT2A/2C/1A receptor agonist hallucinogen N,N-dimethyltryptamine (DMT). Usual desired effects include hallucination, dissociation, mood alteration and perception change. Undesired findings previously reported are nausea, vomiting, hypertension, and tachycardia. All human exposure calls reported to the American Association of Poison Controls Centers' (AAPCC) National Poison Data System (NPDS) between September 1, 2005 and September 1, 2015 were reviewed. Cases were filtered for specific plant derived ayahuasca-related product codes. Abstracted data included the following: case age and gender, exposure reason, exposure route, clinical manifestations, treatments given, medical outcomes and fatality. Five hundred and thirty-eight exposures to ayahuasca botanical products were reported. The majority of the calls to poison control centers came from healthcare facilities (83%). The most common route of exposure was ingestion. Most cases were men (437, 81%, 95% CI 77.7% - 84.3%). The median age was 21 (IQR 18-29). Most exposures were acute. Three hundred thirty-seven (63%) were reported to have a major or moderate clinical effect. The most common clinical manifestations reported were hallucinations (35%), tachycardia (34%), agitation (34%), hypertension (16%), mydriasis (13%) and vomiting (6%). Benzodiazepines were commonly given (30%). There were 28 cases in the series who required endotracheal intubation (5

  14. Analysis of public perception about impaired odor in center fishery processing industry Tegalsari Tegal city

    Science.gov (United States)

    Wibowo, Tri Setyo; Purwanto, P.; Yulianto, Bambang

    2017-03-01

    The Coastal Fishing Port (CFP) Tegalsari is one of the largest center of the fishery industries in Central Java Indonesia. In addition to producing fish-based products such as fish fillets, salted fish and fish meal are distributed to most major cities in Indonesia, but also generate waste and wastewater which potentially disrupt the environment. The purpose of this study describe the perception of the public about the negative impact of the activities in center fishery processing industry. The research method uses qualitative research design with the population living around the center of the fishing industry, with samples taken by purposive sampling numbered 30 people and 3 location sample to know concentration of ammoniac and hydrogen Sulfide. Data research in 2016 was processed using statistical methods. The results of research showed very significant, 80% of respondents who said the fishing activities causing nuisance odor. The remaining 20% stated that the odor nuisance almost imperceptibly. The nuisance of odor are perceived by 53% of respondents for a full day. There are 70% of respondents living around the center of the fishing industry who lived more than seven years, and the remaining 30% of respondents who lived less than 7 years. Conclusion respondent who live more than seven years and said there was no odor nuisance around 57%, are more than 50% of the respondents. The odor of the most influential parameter on the fishing industry is an element of ammoniac (NH3) instead of Hydrogen Sulfide (H2S), because the value at these three locations for Hydrogen Sulfide measurement results show the same number that is equal to 0.001 g/m3. While ammoniac levels at most locations smelled according to perceptions of examiners showed the highest scores, while the zone that did not feel the smell indicates a low value, the test results showed a clear level of distinction. So the need to manage the environment at the center of the fishing industry with a approach of

  15. Technology Assessment: Strategic Energy Analysis Center (SEAC) 2012 Highlights (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2013-02-01

    This fact sheet lists key analysis products produced by NREL in 2012. Like all NREL analysis products, these aim to increase the understanding of the current and future interactions and roles of energy policies, markets, resources, technologies, environmental impacts, and infrastructure. NREL analysis, data, and tools inform decisions as energy-efficient and renewable energy technologies advance from concept to commercial application.

  16. Iron-oxygen vacancy defect centers in PbTi O3 : Newman superposition model analysis and density functional calculations

    Science.gov (United States)

    Meštrić, H.; Eichel, R.-A.; Kloss, T.; Dinse, K.-P.; Laubach, So.; Laubach, St.; Schmidt, P. C.; Schönau, K. A.; Knapp, M.; Ehrenberg, H.

    2005-04-01

    The Fe3+ center in ferroelectric PbTiO3 together with an oxygen vacancy forms a charged defect associate, oriented along the crystallographic c axis. Its microscopic structure has been analyzed in detail comparing results from a semiempirical Newman superposition model analysis based on fine-structure data and from calculations using density functional theory. Both methods give evidence for a substitution of Fe3+ for Ti4+ as an acceptor center. The position of the iron ion in the ferroelectric phase is found to be similar to the B site in the paraelectric phase. Partial charge compensation is locally provided by a directly coordinated oxygen vacancy. Using high-resolution synchrotron powder diffraction, it was verified that lead titanate remains tetragonal down to 12K , exhibiting a c/a ratio of 1.0721.

  17. Geophysical techniques in the historical center of Venice (Italy): preliminary results from HVSR and multichannel analysis of surface waves

    Science.gov (United States)

    Trevisani, Sebastiano; Rocca, Michele; Boaga, Jacopo

    2014-05-01

    This presentation aims to outline the preliminary findings related to an extensive seismic survey conducted in the historical center of Venice, Italy. The survey was conducted via noninvasive and low-cost seismic techniques based on surface waves analysis and microtremor methods, mainly using single station horizontal to vertical spectral ratio techninques (HVSR) and multichannel analysis of surface waves in passive (ReMI) and active (MASW) configurations. The importance and the fragility of the cultural heritage of Venice, coupled with its peculiar geological and geotechnical characteristics, stress the importance of a good knowledge of its geological architecture and seismic characteristics as an opportunity to improve restoration and conservation planning. Even if Venice is located in a relatively low seismic hazard zone, a local characterization of soil resonance frequencies and surficial shear waves velocities could improve the planning of engineering interventions, furnishing important information on possible local effects related to seismic amplification and possible coupling within buildings and soil resonance frequencies. In the specific we collected more than 50 HVSR single station noise measurements and several passive and active multichannel analysis of surface waves located in the historical center. In this work we report the characteristics of the conducted seismic surveys (instrumentation, sampling geometry, etc.) and the preliminary findings of our analysis. Moreover, we discuss briefly the practical issues, mainly of logistic nature, of conducting this kind of surveys in a peculiar and crowed historical center as represented by Venice urban contest. Acknowledgments Instrumentation acquired in relation to the project co-financed by Regione Veneto, POR-CRO, FESR, 2007-2013, action 1.1.1. "Supporto ad attività di ricerca, processi e reti di innovazione e alla creazione di imprese in settori a elevato contenuto tecnologico"

  18. Comparative effectiveness of prostate cancer treatments for patient-centered outcomes: A systematic review and meta-analysis (PRISMA Compliant).

    Science.gov (United States)

    Jayadevappa, Ravishankar; Chhatre, Sumedha; Wong, Yu-Ning; Wittink, Marsha N; Cook, Ratna; Morales, Knashawn H; Vapiwala, Neha; Newman, Diane K; Guzzo, Thomas; Wein, Alan J; Malkowicz, Stanley B; Lee, David I; Schwartz, Jerome S; Gallo, Joseph J

    2017-05-01

    In the context of prostate cancer (PCa) characterized by the multiple alternative treatment strategies, comparative effectiveness analysis is essential for informed decision-making. We analyzed the comparative effectiveness of PCa treatments through systematic review and meta-analysis with a focus on outcomes that matter most to newly diagnosed localized PCa patients. We performed a systematic review of literature published in English from 1995 to October 2016. A search strategy was employed using terms "prostate cancer," "localized," "outcomes," "mortality," "health related quality of life," and "complications" to identify relevant randomized controlled trials (RCTs), prospective, and retrospective studies. For observational studies, only those adjusting for selection bias using propensity-score or instrumental-variables approaches were included. Multivariable adjusted hazard ratio was used to assess all-cause and disease-specific mortality. Funnel plots were used to assess the level of bias. Our search strategy yielded 58 articles, of which 29 were RCTs, 6 were prospective studies, and 23 were retrospective studies. The studies provided moderate data for the patient-centered outcome of mortality. Radical prostatectomy demonstrated mortality benefit compared to watchful waiting (all-cause HR = 0.63 CI = 0.45, 0.87; disease-specific HR = 0.48 CI = 0.40, 0.58), and radiation therapy (all-cause HR = 0.65 CI = 0.57, 0.74; disease-specific HR = 0.51 CI = 0.40, 0.65). However, we had minimal comparative information about tradeoffs between and within treatment for other patient-centered outcomes in the short and long-term. Lack of patient-centered outcomes in comparative effectiveness research in localized PCa is a major hurdle to informed and shared decision-making. More rigorous studies that can integrate patient-centered and intermediate outcomes in addition to mortality are needed.

  19. Chemical analysis of World Trade Center fine particulate matter for use in toxicologic assessment.

    OpenAIRE

    McGee, John K; Chen, Lung Chi; Cohen, Mitchell D.; Chee, Glen R; Prophete, Colette M; Haykal-Coates, Najwa; Wasson, Shirley J; Conner, Teri L; Costa, Daniel L.; Gavett, Stephen H

    2003-01-01

    The catastrophic destruction of the World Trade Center (WTC) on 11 September 2001 caused the release of high levels of airborne pollutants into the local environment. To assess the toxicity of fine particulate matter [particulate matter with a mass median aerodynamic diameter < 2.5 microm (PM2.5)], which may adversely affect the health of workers and residents in the area, we collected fallen dust samples on 12 and 13 September 2001 from sites within a half-mile of Ground Zero. Samples of WTC...

  20. Empirical Analysis of High Efficient Remote Cloud Data Center Backup Using HBase and Cassandra

    Directory of Open Access Journals (Sweden)

    Bao Rong Chang

    2015-01-01

    Full Text Available HBase, a master-slave framework, and Cassandra, a peer-to-peer (P2P framework, are the two most commonly used large-scale distributed NoSQL databases, especially applicable to the cloud computing with high flexibility and scalability and the ease of big data processing. Regarding storage structure, different structure adopts distinct backup strategy to reduce the risks of data loss. This paper aims to realize high efficient remote cloud data center backup using HBase and Cassandra, and in order to verify the high efficiency backup they have applied Thrift Java for cloud data center to take a stress test by performing strictly data read/write and remote database backup in the large amounts of data. Finally, in terms of the effectiveness-cost evaluation to assess the remote datacenter backup, a cost-performance ratio has been evaluated for several benchmark databases and the proposed ones. As a result, the proposed HBase approach outperforms the other databases.

  1. An Analysis of Body Center of Mass Movement during Walking for Power Asisst of Paraplegic Gait

    Science.gov (United States)

    Kagawa, Takahiro; Yamashina, Hideki; Uno, Yoji

    An efficient and stable gait control is an essential problem to develop a legged locomotor device for paraplegics. In this study, we investigate a necessary condition of the ballistic walking to avoid a backward balance loss. The condition derived by an inverted pendulum model is represented as a simple relationship between a position and velocity of a body center of mass at toe-off. The condition was validated through simulation experiments of a 7-link musculoskeletal model and gait measurement experiments of normal and paraplegic subjects. The results of the model simulation showed a good agreement with some predictions of the inverted pendulum model. The measured center of mass trajectories of normal and paraplegic gaits were satisfied with the necessary condition. These results suggest that the necessary condition is effective to avoid a backward falling during walking. In addition, energy input was required in a double support phase while the trajectory followed the ballistic movement of the inverted pendulum in a single support phase for a normal subject. These results suggest that a power assist control to be satisfied with the necessary condition during a double support phase and a ballistic gait generation during a single support phase are required for a paraplegic locomotor with efficiency and stability.

  2. The patient-centered medical home: an ethical analysis of principles and practice.

    Science.gov (United States)

    Braddock, Clarence H; Snyder, Lois; Neubauer, Richard L; Fischer, Gary S

    2013-01-01

    The patient-centered medical home (PCMH), with its focus on patient-centered care, holds promise as a way to reinvigorate the primary care of patients and as a necessary component of health care reform. While its tenets have been the subject of review, the ethical dimensions of the PCMH have not been fully explored. Consideration of the ethical foundations for the core principles of the PCMH can and should be part of the debate concerning its merits. The PCMH can align with the principles of medical ethics and potentially strengthen the patient-physician relationship and aspects of health care that patients value. Patient choice and these ethical considerations are central and at least as important as the economic and practical arguments in support of the PCMH, if not more so. Further, the ethical principles that support key concepts of the PCMH have implications for the design and implementation of the PCMH. This paper explores the PCMH in light of core principles of ethics and professionalism, with an emphasis both on how the concept of the PCMH may reinforce core ethical principles of medical practice and on further implications of these principles.

  3. Analysis of inventory strategies for blood components in a regional blood center using process simulation.

    Science.gov (United States)

    Baesler, Felipe; Nemeth, Matías; Martínez, Cristina; Bastías, Alfonso

    2014-02-01

    The storage of blood components is an important concern in the blood supply chain. Because these are perishable products, the definition of good inventory policies is crucial to reduce shortages and spills. To analyze and propose inventory policies in a regional blood center, a discrete event simulation model was created using simulation software (Arena 12.0, Rockwell Software). The model replicates the activities that are performed along the supply chain including donation arrivals, testing, production, inventory management, and dispatching. Twelve different scenarios were analyzed, with each one representing different inventory policies composed of a combination of an optimal inventory, a reorder point, and a level of extra donations. The best scenario demonstrates that it is possible to decrease unsatisfied demand and wastage of red blood cell units by 2.5 and 3%, respectively, when compared to current practices. This study shows that simulation is an alternative that can be used to model inventory components in blood centers. A responsible selection of inventory variables can improve the capability of the system to respond to the final patient requirements. © 2013 American Association of Blood Banks.

  4. Perievent Panic Attack and Depression after the World Trade Center Disaster: A Structural Equation Model Analysis

    Science.gov (United States)

    Adams, Richard E.; Boscarino, Joseph A.

    2011-01-01

    Research suggests that perievent panic attacks – panic attacks in temporal proximity to traumatic events – are predictive of later mental health status, including the onset of depression. Using a community sample of New York City residents interviewed 1 year and 2 years after the World Trade Center Disaster, we estimated a structural equation model (SEM) using pre-disaster psychological status and post-disaster life events, together with psychosocial resources, to assess the relationship between perievent panic and later onset depression. Bivariate results revealed a significant association between perievent panic and both year-1 and year-2 depression. Results for the SEM, however, showed that perievent panic was predictive of year-1 depression, but not year-2 depression, once potential confounders were controlled. Year-2 stressors and year-2 psychosocial resources were the best predictors of year-2 depression onset. Pre-disaster psychological problems were directly implicated in year-1 depression, but not year-2 depression. We conclude that a conceptual model that includes pre- and post-disaster variables best explains the complex causal pathways between psychological status, stressor exposure, perievent panic attacks, and depression onset two years after the World Trade Center attacks. PMID:21957721

  5. Flow-Log Analysis for Hydraulic Characterization of Selected Test Wells at the Indian Point Energy Center, Buchanan, New York

    Science.gov (United States)

    Williams, John H.

    2008-01-01

    Flow logs from 24 test wells were analyzed as part of the hydraulic characterization of the metamorphosed and fractured carbonate bedrock at the Indian Point Energy Center in Buchanan, New York. The flow logs were analyzed along with caliper, optical- and acoustic-televiewer, and fluid-resistivity and temperature logs to determine the character and distribution of fracture-flow zones and estimate their transmissivities and hydraulic heads. Many flow zones were associated with subhorizontal to shallow-dipping fractured zones, southeast-dipping bedding fractures, northwest-dipping conjugate fractures, or combinations of bedding and conjugate fractures. Flow-log analysis generally provided reasonable first-order estimates of flow-zone transmissivity and head differences compared with the results of conventional hydraulic-test analysis and measurements. Selected results of an aquifer test and a tracer test provided corroborating information in support of the flow-log analysis.

  6. Competitive priorities for service operations strategy: an analysis of the perceived-value criteria of a fitness center

    Directory of Open Access Journals (Sweden)

    Luciano Costa Santos

    2012-01-01

    Full Text Available The setting of priorities among the various performance objectives is one of the main activities in the formulation of manufacturing strategy. Recognizing the importance of this activity and using the nomenclature of “perceived-value criteria”, this paper reports an analysis of competitive priorities of a fitness center, which was an essential part of a broader process aimed at the formulation of operations strategy for the company. After a brief literature review, the article proposes a model for the analysis of perceived-value criteria in service operations that, among other tools, makes use of importance-performance matrix and trade-off analysis. To validate its applicability, the proposed model was field-tested in an action research approach, in which one of the authors of this paper played the role of external facilitator of the process of organizational intervention. The application of the model allowed identifying the processes and the perceived-value criteria (PVC's that should be prioritized by the company, using for this, two bases of comparison: the direct competitors of its influence area and the benchmark fitness centers (best practices. As a result, the firm's managers were able to better decide about the different strategic alternatives to improve its operations.

  7. Competitive Market Analysis of Transplant Centers and Discrepancy of Wait-Listing of Recipients for Kidney Transplantation.

    Science.gov (United States)

    Cho, P S; Saidi, R F; Cutie, C J; Ko, D S C

    2015-01-01

    There are over 250 kidney transplant programs in the USA. To determine if highly competitive regions, defined as regions with a higher number of transplant centers, will approve and wait-list more end-stage renal disease (ESRD) candidates for transplant despite consistent incidence and prevalence of ESRD nationwide. ESRD Network and OPTN data completed in 2011 were obtained from all transplant centers including listing data, market saturation, market share, organs transplanted, and ESRD prevalence. Herfindahl-Hirschman Index (HHI) was used to measure the size of firms in relation to the industry to determine the amount of competition. States were separated into 3 groups (HHI1800 considered highly concentrated). The percentage of ESRD patients listed in competitive, moderate, and highly concentrated regions were 19.73%, 17.02%, and 13.75%, respectively. The ESRD listing difference between competitive versus highly concentrated was significant (pmarket share. Our analysis of the available national data suggests a discrepancy in access for ESRD patient to transplantation due to transplant center competition.

  8. Asset Analysis and Operational Concepts for Separation Assurance Flight Testing at Dryden Flight Research Center

    Science.gov (United States)

    Costa, Guillermo J.; Arteaga, Ricardo A.

    2011-01-01

    A preliminary survey of existing separation assurance and collision avoidance advancements, technologies, and efforts has been conducted in order to develop a concept of operations for flight testing autonomous separation assurance at Dryden Flight Research Center. This effort was part of the Unmanned Aerial Systems in the National Airspace System project. The survey focused primarily on separation assurance projects validated through flight testing (including lessons learned), however current forays into the field were also examined. Comparisons between current Dryden flight and range assets were conducted using House of Quality matrices in order to allow project management to make determinations regarding asset utilization for future flight tests. This was conducted in order to establish a body of knowledge of the current collision avoidance landscape, and thus focus Dryden s efforts more effectively towards the providing of assets and test ranges for future flight testing within this research field.

  9. Transportation Secure Data Center: Real-World Data for Planning, Modeling and Analysis (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2013-01-01

    The National Renewable Energy Laboratory (NREL) and the U.S. Department of Transportation (DOT) have launched the free, web-based Transportation Secure Data Center (TSDC). The TSDC (www.nrel.gov/tsdc) preserves respondent anonymity while making vital transportation data available to a broad group of users through secure, online access. The TSDC database gives, metropolitan planning organizations, universities, national laboratories, air quality management districts, disaster planning agencies and auto manufacturers free-of-charge web-based access to valuable transportation data. The TSDC's two levels of access make composite data available with simple online registration, and allow researchers to use detailed spatial data after completing a straight forward application process.

  10. A Human-Centered Smart Home System with Wearable-Sensor Behavior Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Jianting; Liu, Ting; Shen, Chao; Wu, Hongyu; Liu, Wenyi; Su, Man; Chen, Siyun; Jia, Zhanpei

    2016-11-17

    Smart home has recently attracted much research interest owing to its potential in improving the quality of human life. How to obtain user's demand is the most important and challenging task for appliance optimal scheduling in smart home, since it is highly related to user's unpredictable behavior. In this paper, a human-centered smart home system is proposed to identify user behavior, predict their demand and schedule the household appliances. Firstly, the sensor data from user's wearable devices are monitored to profile user's full-day behavior. Then, the appliance-demand matrix is constructed to predict user's demand on home environment, which is extracted from the history of appliance load data and user behavior. Two simulations are designed to demonstrate user behavior identification, appliance-demand matrix construction and strategy of appliance optimal scheduling generation.

  11. Analysis of strain gage reliability in F-100 jet engine testing at NASA Lewis Research Center

    Science.gov (United States)

    Holanda, R.

    1983-01-01

    A reliability analysis was performed on 64 strain gage systems mounted on the 3 rotor stages of the fan of a YF-100 engine. The strain gages were used in a 65 hour fan flutter research program which included about 5 hours of blade flutter. The analysis was part of a reliability improvement program. Eighty-four percent of the strain gages survived the test and performed satisfactorily. A post test analysis determined most failure causes. Five failures were caused by open circuits, three failed gages showed elevated circuit resistance, and one gage circuit was grounded. One failure was undetermined.

  12. Environmental Modeling Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Environmental Modeling Center provides the computational tools to perform geostatistical analysis, to model ground water and atmospheric releases for comparison...

  13. Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes.

    Science.gov (United States)

    Hadler, Kieran S; Mitić, Natasa; Yip, Sylvia Hsu-Chen; Gahan, Lawrence R; Ollis, David L; Schenk, Gerhard; Larrabee, James A

    2010-03-15

    The glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes is a promiscuous, dinuclear metallohydrolase that has potential application in the remediation of organophosphate nerve agents and pesticides. GpdQ employs an unusual reaction mechanism in which the enzyme is predominantly mononuclear in the resting state, and substrate binding induces the formation of the catalytically competent dinuclear center (Hadler et al. J. Am. Chem. Soc. 2008, 130, 14129). Reactivity is further modulated by the coordination flexibility of Asn80, a ligand that binds to the second, loosely bound metal ion (Hadler et al. J. Am. Chem. Soc. 2009, 131, 11900). It is proposed that hydrolysis is initiated by a terminal, metal-bound hydroxide molecule which is activated at unusually low pH by electrostatic/hydrogen bonding interactions with a bridging hydroxide species. In this study, electronic structure analysis of the dinuclear center is employed to study the coordination environment of the dinuclear center at the resting and product-bound stage of catalysis. This is achieved through the use of variable temperature, variable field magnetic circular dichroism experiments involving the Co(II)-substituted wild type enzyme and its Asn80Asp variant. The data support the above model for the catalytic mechanism whereby the metal ion-bridging hydroxide molecule activates a terminally bound hydroxide nucleophile. Replacement of Asn80 by an aspartate residue does prevent coordination flexibility but also leads to cleavage of the mu-hydroxide bridge and reduced reactivity. This is the first study to investigate the electronic structure of an enzyme with a mu-1,1-carboxylate bridged dicobalt(II) center.

  14. Climate Prediction Center(CPC)Ensemble Canonical Correlation Analysis Forecast of Temperature

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Ensemble Canonical Correlation Analysis (ECCA) temperature forecast is a 90-day (seasonal) outlook of US surface temperature anomalies. The ECCA uses Canonical...

  15. Climate Prediction Center (CPC)Ensemble Canonical Correlation Analysis 90-Day Seasonal Forecast of Precipitation

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Ensemble Canonical Correlation Analysis (ECCA) precipitation forecast is a 90-day (seasonal) outlook of US surface precipitation anomalies. The ECCA uses...

  16. A 5-year retrospective analysis of Necrotizing fasciitis: A single center experiences

    Directory of Open Access Journals (Sweden)

    Kiralj Aleksandar I

    2015-01-01

    Full Text Available Background/Aim. Necrotizing fasciitis (NF is usually an acute infection of superficial fascia with rapid progression in around soft tissue. If not promptly recognized and aggressively treated NF usualy leads to sepsis and multiorgan failure with fatal outcome, thus early diagnosis and prompt surgical treatment are crucial for healing of these patients. The aim of this article was to evaluate the clinical presentation of all patients with acute NF diagnosed and treated in surgical clinics of Clinical Center of Vojvodina, Novi Sad, Serbia. Methods. The medical records of patients treated for acute NF localized on a different parts of the body in Clinical Center of Vojvodina, Novi Sad, Serbia, during a 5- year period (from January 2008 to December 2012 were retrospectively evaluated. This study enrolled patients admitted via Emergency Center of Vojvodina with the diagnosis of acute NF either as the primary diagnosis or with the diagnosis at discharge after surgical treatment. Results. During a 5-year period there were 216 patients with final diagnosis of acute NF. Most of our patients (140 - 64.81% were admitted with the initial diagnosis of cellulitis, abscesses, phlegmons or sepsis. Unfortunately, the clinical symptoms of acute NF were atypical at time of initial examination. Pain and swelling of the affected localization were the most presented bias of symptoms (183 - 84.72%. The majority of our patients were male (164 - 75.92%. Among the 216 patients, the most common pre-existing single factor was drug abuse (39 - 18.05%, followed by obesity (38 - 17.59% and diabetes mellitus (31 - 14.35%. Trauma was most common etiological factor (22 - 10.8% in infected wounds, followed by abdominal (15 - 6.94% and orthopedic (11 - 5.09% surgical intervention. In the present study idiopathic acute NF was diagnosed in 22 (10.18% patients and more than one etiological factor were diagnosed in 20 (9.25% patients. The majority of our patients had type I acute NF

  17. Early liver retransplantation versus late liver retransplantation:analysis of a single-center experience

    Institute of Scientific and Technical Information of China (English)

    CHEN Gui-hua; ZHANG Jun-feng; ZHANG Tong; WANG Guo-ying; FU Bin-sheng; YANG Yang; CAI Chang-jie; LU Min-qiang; LI Hua; WANG Gen-shu; YI Shu-hong; XU Chi

    2008-01-01

    Background Orthotopic liver retransplantation (re-OLT) is the only effective therapy for irreversible failure of a liver graft. Early and late graft failure gives way to two different clinical conditions that should be discussed separately. This study was designed to compare early and late re-OLT for patients with poor graft function after primary transplantation at our center and sum up our clinical experience in re-OLT.Methods The clinical data of 31 re-OLTs at our center from January 2004 to February 2007 were analyzed retrospectively, consisting of the first group with 14 cases of early re-OLT and the second group with 17 cases of late re-OLT.Results Biliary tract complications were the main indications for early re-OLT (57.1%) and late re-OLT (52.9%). Other common indications were vascular complications in early re-OLT and recurrence of primary diseases in late re-OLT. No significant differences were found between the groups with regard to the volume of bleeding during operation, cold ischemia time, operative duration, and perioperative mortality; except for the model of end-stage liver disease (MELD) score. Outcome was fatal for 7 patients in early re-OLT and 9 patients in late re-OLT. Two deaths were due to multiple organ failure with 3 deaths due to severe sepsis-related disease in early re-OLT, and 4 deaths were due to severe sepsis-related disease with 3 deaths due to recurrence of hepatocellular carcinoma (HCC) in late re-OLT. One and 2-year actuarial survival rates after re-OLT were 55.2% and 36.9%, respectively, for patients in early re-OLT, and 65.1% and 52% respectively, for patients in late re-OLT. No significant differences were found regarding survival rates between the two groups.Conclusions Similar clinical results can be achieved in early and late re-OLT. Proper indications and optimal operation timing, adequate preoperative preparation, experienced surgical procedures, and effective perioperative anti-infection strategy contribute to the

  18. Center of gravity and radiographic posture analysis: a preliminary review of adult volunteers and adult patients affected by scoliosis.

    Science.gov (United States)

    El Fegoun, Abdelkrim Benchikh; Schwab, Frank; Gamez, Lorenzo; Champain, Nicolas; Skalli, Wafa; Farcy, Jean-Pierre

    2005-07-01

    This is a prospective radiographic and force plate analysis involving adult volunteer and patients with scoliosis. To assess accurately the center of pressure in standing volunteers and patients with scoliosis, and correlate these finding with radiographic data. A simple and commonly applied parameter of global balance is the plumbline offset. This radiographic measurement refers to the center of C2 (or C7) drawn vertically downward. Although this measurement is simple, it may not accurately reflect the balance of the spine. This study included adult volunteers (n = 41) and patients with scoliosis (n = 45). Full-length, freestanding spine radiographs were obtained with subjects on a force plate. Simultaneous assessment of the radiologic spinal posture and the floor projection of the center of pressure (gravity line) was possible. The latter was projected on the full spine images and correlated to common radiographic parameters. The position of the gravity line differed significantly from the plumbline in frontal and sagittal planes (P gravity line was consistently to the right of the plumbline. The mean sagittal plane alignment of the gravity in relation to the plumbline revealed an offset anteriorly. The data analysis of offsets between the gravity line and radiographic parameters revealed a frontal plane mean displacement of the gravity line to the right. In the sagittal plane, a highly significant lack of correlation between the gravity line and plumbline was noted. The plumbline represents a common and convenient visual display of apparent sagittal plane imbalance, but its value as a marker of true postural balance must be questioned.

  19. [The users of centers for AIDS information and prevention in the Comunidad Valenciana, Spain: a study based on cluster analysis].

    Science.gov (United States)

    González Aracil, J; Ruiz Pérez, I; Aviñó Rico, M J; Hernández Aguado, I

    1999-01-01

    To measure the usefulness of multiple correspondence analysis (MCA) and cluster analysis applied to the epidemiological research of HIV infection. The specific are to explore the relationships between the different variables that characterize the users of the AIDS Information and Prevention Center (CIPS) and to identify clusters of characteristics which in terms of the attendance to these centers, could be considered similar. The clinical history the CIPS in the Valencian region in Spain was used as data source. The target population target were intravenous drug users (IDUSs) attending these centers between 1987 and 1994 (n = 6211). Information about socio-demographic and HIV type I infection-related variables (drug use and sexual behaviour) was collected by means of a semistructured questionnaire. A MCA was carried out to obtain a group of quantitative factors that were used in a cluster analysis. A 44.8% HIV type I prevalence was found. Five factors were detected by MCA that explain 51.14% of the total variability, of which sex, age and the usual sexual partner were the variables best explained. Cluster analysis allowed to describe 5 different subgroups of CIPS users according to their socio-demographics characteristics, risk behaviours and serologic status. It is necessary to highlight the categories 1 and 2, which collect the serologic status and the most relevant characteristics of HIV infection. Category I contains users with a negative serology and characterized by being mainly single adolescent men, with a low educational level; they stated that they have no steady sexual partner, do not share syringes and have been intravenous drug users between 3 and 10 years. They mainly come from the city of Alicante. Category 2 contains mainly people that are HIV positive and older. They also share syringes and have been intravenous drug users for a longer time; they have a higher education level and most of them come from the city of Valencia. The proposed method of

  20. Modeling and Analysis of a Compliance Model and Rotational Precision for a Class of Remote Center Compliance Mechanisms

    Directory of Open Access Journals (Sweden)

    Lei-Jie Lai

    2016-11-01

    Full Text Available The remote center compliance (RCC mechanism is of great use for practical designs, especially if a pure rotation about a virtual point is required. The analysis of compliance properties and rotational precision for RCC mechanisms are very important for mechanical design in applications where precision is required. This paper formulates an analytical method for the compliance and rotational precision calculations of a class of RCC mechanisms, combined in parallel with two round beam-based isosceles-trapezoidal flexural pivots. The analytical model of the mechanism is established based on the stiffness matrix method to directly obtain the compliance factors that completely define the elastic response of the mechanism. The rotational precision of the mechanism—That is, the position of rotation center—Is then derived using screw theory and a compliance matrix. The validity of this model is demonstrated using finite element analysis simulation and experimental tests. The results of both simulation and experiment verify that the analytical model has high accuracy and promising practical applications. Moreover, the influences of the geometry parameters on the compliance factors and the center shifts are also graphically evaluated and discussed using the analytical model. The results in this paper provide an effective configuration and analytical method for the design and optimization of RCC mechanisms, and are of great practical significance.

  1. User-Centered Design for Interactive Maps: A Case Study in Crime Analysis

    Directory of Open Access Journals (Sweden)

    Robert E. Roth

    2015-02-01

    Full Text Available In this paper, we address the topic of user-centered design (UCD for cartography, GIScience, and visual analytics. Interactive maps are ubiquitous in modern society, yet they often fail to “work” as they could or should. UCD describes the process of ensuring interface success—map-based or otherwise—by gathering input and feedback from target users throughout the design and development of the interface. We contribute to the expanding literature on UCD for interactive maps in two ways. First, we synthesize core concepts on UCD from cartography and related fields, as well as offer new ideas, in order to organize existing frameworks and recommendations regarding the UCD of interactive maps. Second, we report on a case study UCD process for GeoVISTA CrimeViz, an interactive and web-based mapping application supporting visual analytics of criminal activity in space and time. The GeoVISTA CrimeViz concept and interface were improved iteratively by working through a series of user→utility→usability loops in which target users provided input and feedback on needs and designs (user, prompting revisions to the conceptualization and functional requirements of the interface (utility, and ultimately leading to new mockups and prototypes of the interface (usability for additional evaluation by target users (user… and so on. Together, the background review and case study offer guidance for applying UCD to interactive mapping projects, and demonstrate the benefit of including target users throughout design and development.

  2. Simultaneous pancreas-kidney transplantation in a single center:10-year retrospective analysis

    Institute of Scientific and Technical Information of China (English)

    ZHENG Jian-ming; SONG Wen-li; TU Jin-peng; FENG Gang; MO Chun-bai; SHEN Zhong-yang

    2011-01-01

    Background Simultaneous pancreas-kidney transplantation (SPKT) is the best treatment option for diabetic patients with advanced chronic renal failure. The current study aimed to analyze the surgical indications, treatments and prognosis of SPKT.Methods We retrospectively analyzed 40 cases of SPKT performed between December 1999 and January 2010 in our center, including the survival rate, complications and the reasons of reoperation.Results Of all the 40 SPKT cases, the one-year survival rates of the recipients, kidney and pancreas transplant graft were 97.6%, 97.6% and 92.7%, while 97.6%, 91.1%, 92.7% at 3 years and 83.6%, 78.0%, 79.4% at 5 years, respectively.After SPKT, 10 patients need reoperation because of surgical complications (14 operations). The reoperation rate was 25%, including 2 patients (4 operations) with hematuria, 4 patients with abdominal hemorrhage, 2 patients (3 operations)with abdominal infection, 1 patient with pancreatic venous thrombosis, 1 patient with anastomotic leakage, and 1 patient with fistula.Conclusion Although SPKT provides a successful and effective treatment for diabetics with end-stage renal disease,how to reduce the complications of this treatment still need further effort.

  3. Analysis of a Student-Centered, Self-Paced Pedagogy Style for Teaching Information Systems Courses

    Directory of Open Access Journals (Sweden)

    Sharon Paranto

    2006-12-01

    Full Text Available The entry-level skills for students enrolling in a college-level information systems course can vary widely. This paper analyzes the impact of a "student-centered" pedagogy model, in which students use a self-paced approach for learning the material in an introductory information systems course, with pre-assigned dates for lectures and for assignment/exam deadlines. This new paradigm was implemented in several sections of an introductory information systems course over a two-semester time span. Under the new model, tutorial-style textbooks were used to help students master the material, all other materials were available online, and all exams were given using a hands-on, task-oriented online testing package, which included a multiple-choice/true-false component to test student understanding of the conceptual portion of the course. An anonymous student survey was used to gain student perceptions of the level of learning that took place under the new paradigm, as well as to measure student satisfaction with the course design, and a pre-/post-test was used to provide a measure of student learning.

  4. A descriptive analysis of patients presenting to psychosexual clinic at a tertiary care center

    Directory of Open Access Journals (Sweden)

    Rohit Verma

    2013-01-01

    Full Text Available Background: Psychosexual problems are very common presentation, be it with psychiatric or physical illness but there are very few studies available on psychosexual disorders especially in the Indian context. Indian society is deeply ingrained in customs and several misconceptions, myths, prejudices, and social taboos are attached to sex which makes it further very difficult to tackle. Objectives: The aim of this current study was to descriptively analyze the nature of sexual disorders in a tertiary care center. Materials and Methods: The current retrospective chart review included 698 consecutive subjects seeking treatment for their psychosexual problems at the Sexual Clinic, Department of Psychiatry, Dr. Ram Manohar Hospital, New Delhi (between 2006 and 2010. Results: This study observed erectile dysfunction (ED (29.5%, Premature ejaculation (PME (24.6%, Dhat syndrome (DS (18.1%, and ED with PME (17.5% as the common sexual dysfunctions leading to treatment seeking. DS was the major complaint among younger and unmarried individuals. We observed more married individuals seeking treatment for sexual disorders. Conclusions: These findings provide important information on a relatively under-researched area.

  5. Acquired hemophilia a: retrospective analysis of 49 cases from a single Chinese hemophilia center.

    Science.gov (United States)

    Yang, Yanhui; Xue, Feng; Shi, Hao; Wang, Hongmei; Zhang, Lei; Ji, Linxiang; Yang, Renchi

    2015-01-01

    Acquired hemophilia A (AHA) is a rare bleeding disorder caused by the autoantibody directed against factor VIII in patients without previous history of a bleeding disorder. We retrospectively analyzed the characteristics and outcomes of 49 patients with AHA diagnosed in our center from February 1994 to October 2012. Twenty-four patients with acute bleeding episodes were treated with prothrombin complex concentrate (PCC) at a relative low dose of 30 to -50 U/kg/d and achieved good outcomes without any adverse reaction. Corticosteroids alone or in combination with cyclophosphamide were used as the first-line therapy to eradicate the inhibitors. In 39 evaluable patients, 35 (89.7%) achieved complete remission (CR). This study demonstrates that when bypassing agents such as recombinant activated factor VII and activated PCCs are not affordable or available, low dose PCC is effective and safe to control acute bleeding in patients with AHA. First-line therapy achieved good outcomes with a CR rate of 89.7%.

  6. A single-center analysis of Henoch-Schonlein purpura nephritis with nephrotic proteinuria in children.

    Science.gov (United States)

    Feng, Dan; Huang, Wen-Yan; Hao, Sheng; Niu, Xiao-Ling; Wang, Ping; Wu, Ying; Zhu, Guang-Hua

    2017-03-04

    In children with Henoch-Schonlein purpura nephritis (HSPN), the degree of proteinuria has been proven to be not only a sign of kidney damage, but also an accelerator of kidney disease progression. Nephrotic proteinuria at disease onset has been proposed as a predictor of a poor renal outcome. This study aims to assess the clinical and pathological features of HSPN with nephrotic proteinuria in a single center. One hundred thirty-seven patients with HSPN who visited Shanghai Children's Hospital from January 2009 to December 2013 were retrospectively reviewed. The patients were divided into 2 groups based on the 24-h urinary protein levels: nephrotic proteinuria group (NP group: 24-h urinary protein ≥50 mg/kg) and non-nephrotic proteinuria group (NNP group: 24-h urinary protein  0.05). The serum albumin and IgG levels of the NP group were significantly lower; however, their blood urea nitrogen and cystatin C levels were higher. The ISKDC grades were mainly above grade III. The prognosis of the NP group was associated with clinical classification and improved after a timely and early treatment.

  7. Human hip joint center analysis for biomechanical design of a hip joint exoskeleton

    Institute of Scientific and Technical Information of China (English)

    Wei YANG; Can-jun YANG‡; Ting XU

    2016-01-01

    We propose a new method for the customized design of hip exoskeletons based on the optimization of the human- machine physical interface to improve user comfort. The approach is based on mechanisms designed to follow the natural tra-jectories of the human hip as the flexion angle varies during motion. The motions of the hip joint center with variation of the flexion angle were measured and the resulting trajectory was modeled. An exoskeleton mechanism capable to follow the hip center’s movement was designed to cover the full motion ranges of flexion and abduction angles, and was adopted in a lower extremity assistive exoskeleton. The resulting design can reduce human-machine interaction forces by 24.1% and 76.0% during hip flexion and abduction, respectively, leading to a more ergonomic and comfortable-to-wear exoskeleton system. The human- exoskeleton model was analyzed to further validate the decrease of the hip joint internal force during hip joint flexion or abduction by applying the resulting design.

  8. Whole blood donor deferral analysis at a center in Western India

    Directory of Open Access Journals (Sweden)

    Agnihotri Naveen

    2010-01-01

    Full Text Available Introduction: Deferrals lead to loss of precious whole blood donors (WBD and blood units available for transfusion purposes. Knowledge of rate and causes of donor deferral can guide the recruitment strategy for WBD. Aim: To find the incidence and causes of deferral in Indian WBD and apply relevant findings to modify recruitment strategy for blood donors. Materials and Methods: Data for WBD presenting for donation in a blood center and outdoor camps over one and half year were analyzed retrospectively. National guidelines were used for selection and deferral of WBD. Result: 736 (11.6% WBD were deferred out of 6357 presenting for donation during the study period. Most (69.8% of the donors were deferred on physical examination and hemoglobin (Hb testing. Most common reasons for deferral were low Hb (55.8%, abnormal blood pressure (11.1%, medication (6.9% and underweight donors (2.9%. Significantly more volunteers were deferred than relative donors (13.97% vs 5.80%; P<0.000. Females were found to have higher deferral rate than males (53.5% vs 6.9%; P=0.000 and higher odds ratio for deferral (15.4. Donors older than 40 years of age had significantly higher chance of being deferred (P<0.05. Discussion and Conclusion: It is important to determine the rate and causes of WBD deferral to guide the recruitment and retention efforts at local, regional, and national level.

  9. An analysis of infrared emission spectra from the regions near the Galactic Center

    CERN Document Server

    Contini, M

    2009-01-01

    We present consistent modelling of line and continuum IR spectra in the region close to the Galactic center. The models account for the coupled effect of shocks and photoionization from an external source. The results show that the shock velocities range between 65 and 80 km/s, the pre-shock densities between 1 cm-3 in the ISM to 200 cm-3 in the filamentary structures. The pre-shock magnetic field increases from 5. 10^{-6} gauss in the surrounding ISM to ~8. 10^{-5} gauss in the Arched Filaments. The stellar temperatures are ~38000 K in the Quintuplet cluster and ~27000 K in the Arches Cluster. The ionization parameter is relatively low (0.01 near the Arches Cluster. Depletion from the gaseous phase of Si is found throughout the whole observed region, indicating the presence of silicate dust. Grains including iron, are concentrated throughout the Arched Filaments. The modelling of the continuum SED in the IR range, indicates that a component of dust at temperatures of ~100-200 K is present in the central regi...

  10. Does the United States economy affect heart failure readmissions? A single metropolitan center analysis.

    Science.gov (United States)

    Thompson, Keith A; Morrissey, Ryan P; Phan, Anita; Schwarz, Ernst R

    2012-08-01

    To determine the effects of the US economy on heart failure hospitalization rates. The recession was associated with worsening unemployment, loss of private insurance and prescription medication benefits, medication nonadherence, and ultimately increased rates of hospitalization for heart failure. We compared hospitalization rates at a large, single, academic medical center from July 1, 2006 to February 28, 2007, a time of economic stability, and July 1, 2008 to February 28, 2009, a time of economic recession in the United States. Significantly fewer patients had private medical insurance during the economic recession than during the control period (36.5% vs 46%; P = 0.04). Despite this, there were no differences in the heart failure hospitalization or readmission rates, length of hospitalization, need for admission to an intensive care unit, in-hospital mortality, or use of guideline-recommended heart failure medications between the 2 study periods. We conclude that despite significant effects on medical insurance coverage, rates of heart failure hospitalization at our institution were not significantly affected by the recession. Additional large-scale population-based research is needed to better understand the effects of fluctuations in the US economy on heart failure hospitalization rates. © 2012 Wiley Periodicals, Inc.

  11. Human Factors Process Task Analysis Liquid Oxygen Pump Acceptance Test Procedure for the Advanced Technology Development Center

    Science.gov (United States)

    Diorio, Kimberly A.

    2002-01-01

    A process task analysis effort was undertaken by Dynacs Inc. commencing in June 2002 under contract from NASA YA-D6. Funding was provided through NASA's Ames Research Center (ARC), Code M/HQ, and Industrial Engineering and Safety (IES). The John F. Kennedy Space Center (KSC) Engineering Development Contract (EDC) Task Order was 5SMA768. The scope of the effort was to conduct a Human Factors Process Failure Modes and Effects Analysis (HF PFMEA) of a hazardous activity and provide recommendations to eliminate or reduce the effects of errors caused by human factors. The Liquid Oxygen (LOX) Pump Acceptance Test Procedure (ATP) was selected for this analysis. The HF PFMEA table (see appendix A) provides an analysis of six major categories evaluated for this study. These categories include Personnel Certification, Test Procedure Format, Test Procedure Safety Controls, Test Article Data, Instrumentation, and Voice Communication. For each specific requirement listed in appendix A, the following topics were addressed: Requirement, Potential Human Error, Performance-Shaping Factors, Potential Effects of the Error, Barriers and Controls, Risk Priority Numbers, and Recommended Actions. This report summarizes findings and gives recommendations as determined by the data contained in appendix A. It also includes a discussion of technology barriers and challenges to performing task analyses, as well as lessons learned. The HF PFMEA table in appendix A recommends the use of accepted and required safety criteria in order to reduce the risk of human error. The items with the highest risk priority numbers should receive the greatest amount of consideration. Implementation of the recommendations will result in a safer operation for all personnel.

  12. Human Factors Process Task Analysis Liquid Oxygen Pump Acceptance Test Procedure for the Advanced Technology Development Center

    Science.gov (United States)

    Diorio, Kimberly A.

    2002-01-01

    A process task analysis effort was undertaken by Dynacs Inc. commencing in June 2002 under contract from NASA YA-D6. Funding was provided through NASA's Ames Research Center (ARC), Code M/HQ, and Industrial Engineering and Safety (IES). The John F. Kennedy Space Center (KSC) Engineering Development Contract (EDC) Task Order was 5SMA768. The scope of the effort was to conduct a Human Factors Process Failure Modes and Effects Analysis (HF PFMEA) of a hazardous activity and provide recommendations to eliminate or reduce the effects of errors caused by human factors. The Liquid Oxygen (LOX) Pump Acceptance Test Procedure (ATP) was selected for this analysis. The HF PFMEA table (see appendix A) provides an analysis of six major categories evaluated for this study. These categories include Personnel Certification, Test Procedure Format, Test Procedure Safety Controls, Test Article Data, Instrumentation, and Voice Communication. For each specific requirement listed in appendix A, the following topics were addressed: Requirement, Potential Human Error, Performance-Shaping Factors, Potential Effects of the Error, Barriers and Controls, Risk Priority Numbers, and Recommended Actions. This report summarizes findings and gives recommendations as determined by the data contained in appendix A. It also includes a discussion of technology barriers and challenges to performing task analyses, as well as lessons learned. The HF PFMEA table in appendix A recommends the use of accepted and required safety criteria in order to reduce the risk of human error. The items with the highest risk priority numbers should receive the greatest amount of consideration. Implementation of the recommendations will result in a safer operation for all personnel.

  13. The Case for Constructing Video Cases: Promoting Complex, Specific, Learner-Centered Analysis of Discussion

    Science.gov (United States)

    Rosaen, Cheryl; Lundeberg, Mary; Terpstra, Marjorie

    2010-01-01

    The use of reflection and analysis in preparation of elementary and secondary preservice teachers has become a standard practice aimed at helping them develop the capacity to engage in intentional and systematic investigation of their practice. Editing video may be a more powerful tool than writing reflections based on memory to help preservice…

  14. User Centered Design as a Framework for Applying Conversation Analysis in Hearing Aid Consultations

    DEFF Research Database (Denmark)

    Egbert, Maria; Matthews, Ben

    2011-01-01

    and Bagger, 1999) and, more recently, Participatory Innovation (Buur and Matthews, 2008) which is uniquely compatible with conversation analysis. Designers following this approach study how a ‘user’ of goods or services interacts with products and other interaction partners in order to derive ideas...

  15. The Case for Constructing Video Cases: Promoting Complex, Specific, Learner-Centered Analysis of Discussion

    Science.gov (United States)

    Rosaen, Cheryl; Lundeberg, Mary; Terpstra, Marjorie

    2010-01-01

    The use of reflection and analysis in preparation of elementary and secondary preservice teachers has become a standard practice aimed at helping them develop the capacity to engage in intentional and systematic investigation of their practice. Editing video may be a more powerful tool than writing reflections based on memory to help preservice…

  16. Asian Students' Conceptions of Future Civic Engagement: Comparing Clusters Using Person-Centered Analysis

    Science.gov (United States)

    Chow, Joseph Kui Foon; Kennedy, Kerry J.

    2015-01-01

    Researchers in comparative education have suggested different ways in which their field of study can be enhanced by considering units of analysis at different levels rather than focusing on a single level such as the nation-state (Bray and Thomas, 1995; Torney-Purta and Barber, 2011). The study reported here seeks to contribute to this area of…

  17. Healthcare Resource Utilization Associated with Burns and Necrotizing Fasciitis: A Single-Center Comparative Analysis.

    Science.gov (United States)

    Burnett, Eileen; Gawaziuk, Justin P; Shek, Kevin; Logsetty, Sarvesh

    2017-03-06

    Necrotizing fasciitis (NF) patients are increasingly managed in burn units. Although treated similarly to burns, the healthcare resource utilization (HRU) in NF appears to be greater. Accurate knowledge of the HRU is important to better allocate resources and to compare outcomes between units. The goal of this study is to provide better understanding of the HRU for NF compared with burns. A retrospective chart review of patients ≥18 years admitted to two regional tertiary referral centers with either NF or burns requiring surgery. The authors examined age, sex, %TBSA, geographic region, anatomical location, length of stay (LOS) in hospital, LOS in intensive care unit, number of operative procedures, number of packed red blood cells transfused, amputation, death, and use of free tissue transfer or skin graft. There were 210 NF and 209 burn patients. The NF cohort had a smaller TBSA (3.3 vs 10.0%), longer LOS (20 vs 14 days), and consequently a longer LOS/%TBSA (6.0 vs 1.5 days). This difference persisted after adjusting for age. More of the NF cohort (44.8%) spent ≥1 day in the intensive care unit. The NF cohort also had more procedures (median 2 vs 1), required blood (46.2 vs 16.7%), died in hospital (13.3 vs 4.3%), had an amputation (12.4 vs 4.8%), or required free tissue transfer (7.6 vs 2.9%). This study shows that NF requires substantially more HRU compared with burns. This information is important in recognizing the impact of these patients on burn units and planning for allocation of appropriate resources.

  18. An Analysis of Cloud Computing with Amazon Web Services for the Atmospheric Science Data Center

    Science.gov (United States)

    Gleason, J. L.; Little, M. M.

    2013-12-01

    NASA science and engineering efforts rely heavily on compute and data handling systems. The nature of NASA science data is such that it is not restricted to NASA users, instead it is widely shared across a globally distributed user community including scientists, educators, policy decision makers, and the public. Therefore NASA science computing is a candidate use case for cloud computing where compute resources are outsourced to an external vendor. Amazon Web Services (AWS) is a commercial cloud computing service developed to use excess computing capacity at Amazon, and potentially provides an alternative to costly and potentially underutilized dedicated acquisitions whenever NASA scientists or engineers require additional data processing. AWS desires to provide a simplified avenue for NASA scientists and researchers to share large, complex data sets with external partners and the public. AWS has been extensively used by JPL for a wide range of computing needs and was previously tested on a NASA Agency basis during the Nebula testing program. Its ability to support the Langley Science Directorate needs to be evaluated by integrating it with real world operational needs across NASA and the associated maturity that would come with that. The strengths and weaknesses of this architecture and its ability to support general science and engineering applications has been demonstrated during the previous testing. The Langley Office of the Chief Information Officer in partnership with the Atmospheric Sciences Data Center (ASDC) has established a pilot business interface to utilize AWS cloud computing resources on a organization and project level pay per use model. This poster discusses an effort to evaluate the feasibility of the pilot business interface from a project level perspective by specifically using a processing scenario involving the Clouds and Earth's Radiant Energy System (CERES) project.

  19. Central nervous system imaging in childhood Langerhans cell histiocytosis – a reference center analysis

    Science.gov (United States)

    Porto, Luciana; Schöning, Stefan; Hattingen, Elke; Sörensen, Jan; Jurcoane, Alina; Lehrnbecher, Thomas

    2015-01-01

    Background The aim of our study was (1) to describe central nervous system (CNS) manifestations in children with Langerhans cell histiocytosis (LCH) based on images sent to a reference center and meeting minimum requirements and (2) to assess the inter-rater agreement of CNS-MRI results, which represents the overall reproducibility of this investigation. Methods We retrospectively reviewed brain MRI examinations in children with LCH, for which MRI minimum requirements were met. Abnormalities were rated by two experienced neuroradiologists, and the inter-rater agreement was assessed. Results Out of a total of 94 imaging studies, only 31 MRIs met the minimum criteria, which included T2w, FLAIR, T1w images before/after contrast in at least two different section planes, and thin post contrast sagittal slices T1w through the sella. The most common changes were osseous abnormalities, followed by solid enlargement of the pineal gland, thickened enhancing stalk and signal changes of the dentate nucleus. Whereas inter-rater agreement in assessing most of the CNS lesions was relatively high (κ > 0.61), the application of minimum criteria often did not allow to evaluate the posterior pituitary. Conclusions The diversity of radiological protocols from different institutions leads to difficulties in the diagnosis of CNS abnormalities in children with LCH. Although the inter-rater agreement between neuroradiologists was high, not all the LCH manifestations could be completely ruled out when using the minimum criteria. Brain MRIs should therefore follow LCH guideline protocols and include T1 pre-gadolinium sagittal images, and be centrally reviewed in order to improve the comparison of clinical trials. PMID:26401129

  20. Budget Impact Analysis of Peritoneal Dialysis versus Conventional In-Center Hemodialysis in Malaysia.

    Science.gov (United States)

    Bavanandan, Sunita; Ahmad, Ghazali; Teo, Ai-Hong; Chen, Lilian; Liu, Frank Xiaoqing

    2016-05-01

    To investigate the 5-year health care budget impact of variable distribution of adult patients treated with peritoneal dialysis (PD) and in-center hemodialysis (ICHD) on government funding in Malaysia. An Excel-based budget impact model was constructed to assess dialysis-associated costs when changing dialysis modalities between PD and ICHD. The model incorporates the current modality distribution and accounts for Malaysian government dialysis payments and erythropoiesis-stimulating agent costs. Epidemiological data including dialysis prevalence, incidence, mortality, and transplant rates from the Malaysian renal registry reports were used to estimate the dialysis patient population for the next 5 years. The baseline scenario assumed a stable distribution of PD (8%) and ICHD (92%) over 5 years. Alternative scenarios included the prevalence of PD increasing by 2.5%, 5.0%, and 7.5% or decreasing 1% yearly over 5 years. All four scenarios were accompanied with commensurate changes in ICHD. Under the current best available cost information, an increase in the prevalent PD population from 8% in 2014 to 18%, 28%, or 38% in 2018 is predicted to result in 5-year cumulative savings of Ringgit Malaysia (RM) 7.98 million, RM15.96 million, and RM23.93 million, respectively, for the Malaysian government. If the prevalent PD population were to decrease from 8% in 2014 to 4.0% by 2018, the total expenditure for dialysis treatments would increase by RM3.19 million over the next 5 years. Under the current cost information associated with PD and HD paid by the Malaysian government, increasing the proportion of patients on PD could potentially reduce dialysis-associated costs in Malaysia. Copyright © 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  1. Mechanical Revascularization for Acute Ischemic Stroke: A Single-Center, Retrospective Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jeromel, Miran, E-mail: miran.jeromel@gmail.com; Milosevic, Z. V., E-mail: zoran.milosevic@guest.arnes.si; Kocijancic, I. J., E-mail: igor.kocijancic@gmail.com; Lovric, D., E-mail: dimitrijlavric@yahoo.com [University Medical Centre Ljubljana, Clinical Institute of Radiology, Department for Diagnostic and Interventional Neuroradiology (Slovenia); Svigelj, V., E-mail: viktor.svigelj@gmail.com; Zvan, B., E-mail: bojana.zvan@guest.arnes.si [University Medical Centre Ljubljana, Division Vascular and Intensive Neurology, Department of Neurology (Slovenia)

    2013-04-15

    BackgroundEndovascular mechanical revascularization (thrombectomy) is an increasingly used method for intracranial large vessel recanalization in acute stroke. The purpose of the study was to analyze the recanalization rate, clinical outcome, and complication rate in our stroke patients treated with mechanical revascularization. A total of 57 patients with large vessel stroke (within 3 h for anterior and 12 h for posterior circulation) were treated with mechanical revascularization at a single center during 24 months. The primary goal of endovascular treatment using different mechanical devices was recanalization of the occluded vessel. Recanalization rate (reported as thrombolysis in cerebral infarction [TICI] score), clinical outcome (reported as National Institutes of Health Stroke Scale [NIHSS] score and modified Rankin scale [mRS] score), as well as periprocedural complications were analyzed. The mean age of the patients was 63.1 {+-} 12.9 years, with baseline median NIHSS score of 14 (interquartile range, 9.5-19). Successful recanalization (TICI 2b or 3) was achieved in 41 (72 %) patients. Twenty patients (35 %) presented with favorable outcome (mRS {<=}2) 30 days after stroke. Overall, significant neurological improvement ({>=}4 NIHSS point reduction) occurred in 36 (63 %) patients. A clinically significant procedure-related adverse events (vessel disruption, peri/postprocedural intracranial bleeding) defined with decline in NIHSS of {>=}4 or death occurred in three (5 %) patients. The study showed a high recanalization rate with improved clinical outcome and a low rate of periprocedural complications in our stroke patients treated with mechanical revascularization. Therefore, we could conclude that endovascular revascularization (primary or in combination with a bridging thrombolysis) was an effective and safe procedure for intracranial large vessel recanalization in acute stroke.

  2. AT-09BEVACIZUMAB AND GLIOBASTOMA OF THE ELDERLY: A SINGLE-CENTER RETROSPECTIVE ANALYSIS

    Science.gov (United States)

    Barrascout, Eduardo; Lamuraglia, Michele; Gervais, Claire; Tiako, Manuela; Gaillard, Stephan; Aldea, Sorin; Mabro, May; Gachet, Julie; Theodore, Christine

    2014-01-01

    PURPOSE: The primary objective of this study was to determine any difference in progression free survival (PFS), overall survival (OS), clinical benefit and tolerability between elderly and non-elderly patients receiving bevacizumab at recurrence for glioblastoma in a single center. PATIENTS AND METHODS: We retrospectively analyzed 32 patients with recurrent glioblastoma receiving bevacizumab (10 mg/kg every 14 days) between January 2011 and December 2013 in second line. Bevacizumab was introduced for all patients at recurrence after a treatment of first line by temozolomide. A cohort of 14 patients was older than 70 years against 18 patients were under 70 years. RESULTS: No statistically significant difference was detected in terms of PFS and OS. PFS was 2.8 months for elderly patients against 2.9 for non-elderly patients (p >0.5). OS from recurrence in elderly and non-elderly patients was respectively 4.3 and 5.5 months (p >0,5). Clinical improvement in neurological symptoms was observed in 3 of 14 elderly patients (21.1%) and 11 of 18 young patients (61.1%). A more important improvement in performance status was observed in young patients. Regarding toxicity, 3 of the 14 elderly patients experienced grade II or III hypertension. In younger patients, 5 adverse events have been observed (2 proteinuria, 1 hypertension, 1 hemorrhage and 1 anal abscess). CONCLUSION: Despite small number of patients in this retrospective study, the efficacy and safety of bevacizumab in recurrent glioblastoma appears similar in elderly and non-elderly patients. However, clinical benefit seemed to be less important in elderly patients. A prospective multicentric study integrating geriatric assessment tools and quality of life would be interesting in this patient's population.

  3. Structural and spectropotentiometric analysis of Blastochloris viridis heterodimer mutant reaction center

    Energy Technology Data Exchange (ETDEWEB)

    Ponomarenko, Nina S.; Li, Liang; Marino, Antony R.; Tereshko, Valentina; Ostafin, Agnes; Popova, Julia A.; Bylina, Edward J.; Ismagilov, Rustem F.; Norris, Jr., James R.; (UC); (Utah)

    2010-07-22

    Heterodimer mutant reaction centers (RCs) of Blastochloris viridis were crystallized using microfluidic technology. In this mutant, a leucine residue replaced the histidine residue which had acted as a fifth ligand to the bacteriochlorophyll (BChl) of the primary electron donor dimer M site (HisM200). With the loss of the histidine-coordinated Mg, one bacteriochlorophyll of the special pair was converted into a bacteriopheophytin (BPhe), and the primary donor became a heterodimer supermolecule. The crystals had dimensions 400 x 100 x 100 {micro}m, belonged to space group P4{sub 3}2{sub 1}2, and were isomorphous to the ones reported earlier for the wild type (WT) strain. The structure was solved to a 2.5 {angstrom} resolution limit. Electron-density maps confirmed the replacement of the histidine residue and the absence of Mg. Structural changes in the heterodimer mutant RC relative to the WT included the absence of the water molecule that is typically positioned between the M side of the primary donor and the accessory BChl, a slight shift in the position of amino acids surrounding the site of the mutation, and the rotation of the M194 phenylalanine. The cytochrome subunit was anchored similarly as in the WT and had no detectable changes in its overall position. The highly conserved tyrosine L162, located between the primary donor and the highest potential heme C{sub 380}, revealed only a minor deviation of its hydroxyl group. Concomitantly to modification of the BChl molecule, the redox potential of the heterodimer primary donor increased relative to that of the WT organism (772 mV vs. 517 mV). The availability of this heterodimer mutant and its crystal structure provides opportunities for investigating changes in light-induced electron transfer that reflect differences in redox cascades.

  4. Systems genomics analysis centered on epigenetic inheritance supports development of a unified theory of biology.

    Science.gov (United States)

    Sharma, Abhay

    2015-11-01

    New discoveries are increasingly demanding integration of epigenetics, molecular biology, genomic networks and physiology with evolution. This article provides a proof of concept for evolutionary transgenerational systems biology, proposed recently in the context of epigenetic inheritance in mammals. Gene set enrichment analysis of available genome-level mammalian data presented here seem consistent with the concept that: (1) heritable information about environmental effects in somatic cells is communicated to the germline by circulating microRNAs (miRNAs) or other RNAs released in physiological fluids; (2) epigenetic factors including miRNA-like small RNAs, DNA methylation and histone modifications are propagated across generations via gene networks; and (3) inherited epigenetic variations in the form of methylated cytosines are fixed in the population as thymines over the evolutionary time course. The analysis supports integration of physiology and epigenetics with inheritance and evolution. This may catalyze efforts to develop a unified theory of biology.

  5. Interactive data analysis for astronomy Shuttle experiments at Goddard Space Flight Center

    Science.gov (United States)

    Klinglesmith, D. A., III

    1981-01-01

    The eye as an efficient selection device for determining what is important in astronomical imagery can be greatly aided by the computer. A suitable facility, called the Interactive Astronomical Data Analysis Facility (IADAF), has been developed for the display and analysis of astronomical imagery by the Laboratory for Astronomy and Solar Physics. The Laboratory for Astronomy and Solar Physics currently has approval to fly two experiments on Spacelab. The Solar Extreme Ultraviolet Telescope (SEUTS) is to be used for the study of several fundamental problems of solar physics. The Ultraviolet Image Telescope for Astronomical Investigations (UIT) is to provide direct imagery of selected fields of view throughout the sky. A description is given of IADAF, taking into account its 16-bit computer and the COMTAL image processing display system. The use of IADAF by SEUTS and UIT is discussed.

  6. Robust Analysis of the Joint Strike Fighter Integrated Training Center Pilot Scheduling

    Science.gov (United States)

    2011-09-01

    models weather using Markov chains and a weather resource, since weather conditions for consecutive events are not independent (Dummar, 2011). He...justification for procurement or as an explanation for bottlenecks in the system. The ITC model is a discrete-event, first-in first-out, queuing -based...Unfortunately, queuing theory tells us that this will likely bias the results (Ross, 2007). In robust analysis, the intent is to look at the effect of

  7. A Policy Analysis for the Implementation of the Generic Inventory Package in a Medical Center Engineering Supply Warehouse

    Science.gov (United States)

    2007-12-01

    194,600 veterans in a primary service area that includes 49 counties in Utah, Idaho, Nevada , and Wyoming. The VASLCHCS provides medical, surgical...20 Med Center Profile - Northport ------------ 23 Med Center Profile - John J. Pershing ----- 27 Med Center Profile - Muskogee ------------- 29 Med...John J. Pershing VA Medical Center in Popular Bluff, Missouri, and the Muskogee VA Medical Center in Muskogee, Oklahoma. The Veteran’s Affairs

  8. Control of oscillation periods and phase durations in half-center central pattern generators: a comparative mechanistic analysis.

    Science.gov (United States)

    Daun, Silvia; Rubin, Jonathan E; Rybak, Ilya A

    2009-08-01

    Central pattern generators (CPGs) consisting of interacting groups of neurons drive a variety of repetitive, rhythmic behaviors in invertebrates and vertebrates, such as arise in locomotion, respiration, mastication, scratching, and so on. These CPGs are able to generate rhythmic activity in the absence of afferent feedback or rhythmic inputs. However, functionally relevant CPGs must adaptively respond to changing demands, manifested as changes in oscillation period or in relative phase durations in response to variations in non-patterned inputs or drives. Although many half-center CPG models, composed of symmetric units linked by reciprocal inhibition yet varying in their intrinsic cellular properties, have been proposed, the precise oscillatory mechanisms operating in most biological CPGs remain unknown. Using numerical simulations and phase-plane analysis, we comparatively investigated how the intrinsic cellular features incorporated in different CPG models, such as subthreshold activation based on a slowly inactivating persistent sodium current, adaptation based on slowly activating calcium-dependent potassium current, or post-inhibitory rebound excitation, can contribute to the control of oscillation period and phase durations in response to changes in excitatory external drive to one or both half-centers. Our analysis shows that both the sensitivity of oscillation period to alterations of excitatory drive and the degree to which the duration of each phase can be separately controlled depend strongly on the intrinsic cellular mechanisms involved in rhythm generation and phase transitions. In particular, the CPG formed from units incorporating a slowly inactivating persistent sodium current shows the greatest range of oscillation periods and the greatest degree of independence in phase duration control by asymmetric inputs. These results are explained based on geometric analysis of the phase plane structures corresponding to the dynamics for each CPG type

  9. Using efficiency analysis and targeted intervention to improve operational performance and achieve cost savings in the endoscopy center.

    Science.gov (United States)

    Kaushal, Neal K; Chang, Kenneth; Lee, John G; Muthusamy, V Raman

    2014-04-01

    With an increasing demand for endoscopy services, there is a greater need for efficiency within the endoscopy center. A validated methodology is important for evaluating efficiency in the endoscopy unit. To use the principles of operations management to establish a validated methodology for evaluating and enhancing operational performance in the endoscopy center. Biphasic prospective study with pre-intervention and post-intervention efficiency data and analysis. Tertiary-care referral teaching hospital. Scheduled outpatients undergoing endoscopy. Determination of the rate-limiting step, or bottleneck, of the endoscopy unit and reducing inefficiencies. Staffing costs and a novel performance metric, True Completion Time (TCT). Data were prospectively recorded for 2248 patients undergoing a total of 2713 procedures (phase I: 255 EGD, 305 colonoscopy, 91 EGD/colonoscopy, 375 EUS, 44 ERCP, 75 EUS/ERCP; phase II: 243 EGD, 328 colonoscopy, 99 EGD/colonoscopy, 335 EUS, 38 ERCP, 109 EUS/ERCP). The bottleneck of the operation was identified as the 10-bed communal pre-procedure/recovery room. On-time procedure starts increased by 51% (P costs were reduced by 30%, whereas full-time employee staff was reduced by 0.85. Annual cost savings were calculated as $312,618 or 11.02% of total operating expenses. This study is not directly tied to quality outcomes, and inpatient procedures transported to the endoscopy unit were not directly studied. Room turnover time and room-to-endoscopist ratio are not necessarily the driving parameters behind endoscopy unit efficiency. A focus on developing a methodology for identifying factors constraining operational efficiency can improve performance and reduce costs in the endoscopy center. Copyright © 2014 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

  10. Cluster analysis of autoantibodies in 852 patients with systemic lupus erythematosus from a single center.

    Science.gov (United States)

    Artim-Esen, Bahar; Çene, Erhan; Şahinkaya, Yasemin; Ertan, Semra; Pehlivan, Özlem; Kamali, Sevil; Gül, Ahmet; Öcal, Lale; Aral, Orhan; Inanç, Murat

    2014-07-01

    Associations between autoantibodies and clinical features have been described in systemic lupus erythematosus (SLE). Herein, we aimed to define autoantibody clusters and their clinical correlations in a large cohort of patients with SLE. We analyzed 852 patients with SLE who attended our clinic. Seven autoantibodies were selected for cluster analysis: anti-DNA, anti-Sm, anti-RNP, anticardiolipin (aCL) immunoglobulin (Ig)G or IgM, lupus anticoagulant (LAC), anti-Ro, and anti-La. Two-step clustering and Kaplan-Meier survival analyses were used. Five clusters were identified. A cluster consisted of patients with only anti-dsDNA antibodies, a cluster of anti-Sm and anti-RNP, a cluster of aCL IgG/M and LAC, and a cluster of anti-Ro and anti-La antibodies. Analysis revealed 1 more cluster that consisted of patients who did not belong to any of the clusters formed by antibodies chosen for cluster analysis. Sm/RNP cluster had significantly higher incidence of pulmonary hypertension and Raynaud phenomenon. DsDNA cluster had the highest incidence of renal involvement. In the aCL/LAC cluster, there were significantly more patients with neuropsychiatric involvement, antiphospholipid syndrome, autoimmune hemolytic anemia, and thrombocytopenia. According to the Systemic Lupus International Collaborating Clinics damage index, the highest frequency of damage was in the aCL/LAC cluster. Comparison of 10 and 20 years survival showed reduced survival in the aCL/LAC cluster. This study supports the existence of autoantibody clusters with distinct clinical features in SLE and shows that forming clinical subsets according to autoantibody clusters may be useful in predicting the outcome of the disease. Autoantibody clusters in SLE may exhibit differences according to the clinical setting or population.

  11. Erectile Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Outcomes from a Multi-Center Study and Risk Factor Analysis in a Single Center.

    Directory of Open Access Journals (Sweden)

    Yadong Zhang

    Full Text Available The aim of this study was to investigate the prevalence of erectile dysfunction (ED in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS and explore the influence of UPOINT domains, National Institutes of Health-CP symptom index (NIH-CPSI and other factors on ED prevalence. This was a prospective study of consecutive patients with CP/CPPS seen at 11 tertiary hospitals during January-July 2014. ED was diagnosed as a score of<21 on the International Index of Erectile Function (IIEF-5. Patients from one center were evaluated by the UPOINT system and NIH-CPSI. Each patient was assessed using clinical examination, asocio-demographic questionnaire, the Patient Health Questionnaire (PHQ, the Pain Catastrophizing Scale (PCS, NIH-CPSI and IIEF-5.1406 patients from 11 centers (mean age, 32.18 years; range 18-60 years were enrolled. ED was found in 638/1406 patients (45.4%, and was categorized as mild in 291(45.6%, moderate in 297(46.6% and severe in50(7.7%. 192 patients from one center(mean age,31.3 years; range 18-57 years were further studied.IIEF-5 score correlated negatively with NIH-CPSI(r = 0.251, PHQ (r = 0.355 and PCS (r = 0.322scores (P<0.001.PHQ score correlated positively with NIH-CPSI (r = 0.586 and PCS(r = 0.662 scores (P<0.001.NIH-CPSI, PHQ, PCS and IIEF-5 scores did not differ significantly between class IIIA and IIIB CP/CPPS. Multivariate logistic regression showed that UPOINT psychological (P domain and NIH-CPSI symptom severity were independent risk factors for ED in CP/CPPS. It is concluded that psychological factors and symptom severity are independent risk factors for ED in CP/CPPS.

  12. Analysis of endoscopic management of occluded metal biliary stents at a single tertiary care center.

    Science.gov (United States)

    Rogart, Jason N; Boghos, Ara; Rossi, Federico; Al-Hashem, Hashem; Siddiqui, Uzma D; Jamidar, Priya; Aslanian, Harry

    2008-10-01

    A significant number of self-expandable metal stents (SEMSs) placed to palliate malignant biliary obstruction will occlude. Few data exist as to what constitutes optimal management. Our purpose was to review the management and outcomes of patients with biliary SEMS occlusion. Retrospective chart review at a single tertiary care hospital. From January 1999 to October 2005, a total of 90 patients had SEMSs placed for malignant biliary obstruction, and 27 of these occluded. Technical success of treating SEMS occlusion, stent patency and need for reintervention, and incremental cost analysis. A total of 60 ERCPs were performed to treat SEMS occlusions in 27 patients. The success rate was 95%; however, 52% of patients eventually required more than 1 intervention. Placing a second SEMS through the existing SEMS (n = 14) provided the lowest reocclusion rate (43% vs 55% and 100%), the longest time to reintervention (172 days vs 66 and 43 days, P = .03), and a trend toward longer survival (285 days vs 188 and 194 days) compared with plastic stent and mechanical balloon cleaning, respectively. Incremental cost analysis showed both uncovered SEMSs and plastic stents to be cost effective strategies. Small number of patients, retrospective study. Treatment of biliary SEMS occlusion with SEMS insertion provides for longer patency and survival, decreases the number of subsequent ERCPs by 50% compared with plastic stents, and is cost-effective.

  13. BIOIMPEDANCE ANALYSIS IN HAEMODIALYSIS PRACTICE: SHORT REVIEW AND SINGLE CENTER EXPERIENCE

    Directory of Open Access Journals (Sweden)

    A.G. Strokov

    2012-01-01

    Full Text Available Bioimpedance analysis has been widely used to estimate a hydration state, lean and fat mass in haemodialysis patients. The aim of our study was to investigate the validity and usefulness of bioimpedance analysis in routine dialysis practice. Last two years we used the body composition monitoring (BCM, Fresenius Medical Care, method based on whole body multifrequency bioimpedance spectroscopy (BIS, compared with traditional clinical data. For BIS data verification, hydration status of 32 stable HD patients with dialysis vintage more than 3 years and clinically well established dry weight were studied. Only in three cases BIS data seems underestimated in serial measurements. Next step, 28 healthy subjects and 116 dialysis patients were studied. Total body water and extracellular volume (ECV were significantly higher in dialysis group (P<0.01, and there was not any difference in intracellular volume (ICV. Mean AP was similar in patients with moderate (<15% and massive (>15% relative overhydration (RO = overhydration / ECV, at the same time, average number of antihypertensive medications was significantly higher in more overhydrated patients (3.1 vs 1.2. In clinical practice RO is more convenient indicator as compared to standard overhydration volume /dry weight ratio. Mutual application of the BIS and blood volume monitoring allows more rapid and safe dry weight achievement. BIS was useful tool for hydration status monitoring in routine haemodialysis practice, and further work need to be done to clarify BIS validity for nutritional status estimation. 

  14. Country analysis briefs: 1994. Profiles of major world energy producers, consumers, and transport centers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    Country Analysis Briefs: 1994 is a compilation of country profiles prepared by the Energy Markets and Contingency Information Division (EMCID) of the Office of Energy Markets and End Use. EMCID maintains Country Analysis Briefs (CABs) for specific countries or geographical areas that are important to world energy markets. As a general rule, CABs are prepared for all members of the Organization of Petroleum Exporting Countries (OPEC), major non-OPEC oil producers (i.e., the North Sea, Russia), major energy transit areas (i.e., Ukraine), and other areas of current interest to energy analysts and policy makers. As of January 1995, EMCID maintained over 40 CABs, updated on an annual schedule and subject to revision as events warrant. This report includes 25 CABs updated during 1994. All CABs contain a profile section, a map showing the country`s location, and a narrative section. The profile section includes outlines of the country`s economy, energy sector, and environment. The narrative provides further information and discussion of these topics. Some CABs also include a detailed map displaying locations of major oil and gas fields, pipelines, ports, etc. These maps were created as a result of special individual requests and so are not typically a standard feature of the CABs. They are presented here wherever available as a supplement to the information contained in the CABs.

  15. Role of Theories in the Design of Web-Based Person-Centered Support: A Critical Analysis.

    Science.gov (United States)

    Ranerup, Agneta; Sparud-Lundin, Carina; Koinberg, Ingalill; Skärsäter, Ingela; Jenholt-Nolbris, Margaretha; Berg, Marie

    2014-01-01

    Objective. The aim of this study was to provide a critical understanding of the role of theories and their compatibility with a person-centered approach in the design and evaluation of web-based support for the management of chronic illness. Methods. Exploration of web-based support research projects focusing on four cases: (1) preschool children aged 4-6 with bladder dysfunction and urogenital malformation; (2) young adults aged 16-25 living with mental illness; (3) women with type 1 diabetes who are pregnant or in early motherhood; and (4) women who have undergone surgery for breast cancer. Data comprised interviews with research leaders and documented plans. Analysis was performed by means of a cross-case methodology. Results. The used theories concerned design, learning, health and well-being, or transition. All web support products had been developed using a participatory design (PD). Fundamental to the technology design and evaluation of outcomes were theories focusing on learning and on health and well-being. All theories were compatible with a person-centered approach. However, a notable exception was the relatively collective character of PD and Communities of Practice. Conclusion. Our results illustrate multifaceted ways for theories to be used in the design and evaluation of web-based support.

  16. PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP ENTITLED "GLOBAL ANALYSIS OF POLARIZED PARTON DESTRIBUTIONS IN THE RHIC ERA" (VOLUME 86).

    Energy Technology Data Exchange (ETDEWEB)

    DESHPANDE,A.; VOGELSANG, W.

    2007-10-08

    The determination of the polarized gluon distribution is a central goal of the RHIC spin program. Recent achievements in polarization and luminosity of the proton beams in RHIC, has enabled the RHIC experiments to acquire substantial amounts of high quality data with polarized proton beams at 200 and 62.4 GeV center of mass energy, allowing a first glimpse of the polarized gluon distribution at RHIC. Short test operation at 500 GeV center of mass energy has also been successful, indicating absence of any fundamental roadblocks for measurements of polarized quark and anti-quark distributions planned at that energy in a couple of years. With this background, it has now become high time to consider how all these data sets may be employed most effectively to determine the polarized parton distributions in the nucleon, in general, and the polarized gluon distribution, in particular. A global analysis of the polarized DIS data from the past and present fixed target experiments jointly with the present and anticipated RHIC Spin data is needed.

  17. MATHEMATICAL ANALYSIS OF HOW THE ELECTRICAL TRAINING CENTER SITE IS AFFECTED BY AIR POLLUTION

    Directory of Open Access Journals (Sweden)

    Bassam A. Al-Helou

    2012-01-01

    Full Text Available The study has come to the result that the monitoring site at the Electrical Training Centre (ETC at Al-Hashimyeh town is exposed to grave pollution that goes beyond Jordanian standards of the ambient air. It has, indeed, shown that Sulfur dioxide (SO2 exceeds the limits and its seasonal concentration matches forward with the average wind speed. SO2 concentration reaches its lowest level in the early morning of the day and its highest level at the end of the day. The study has also pointed out that the levels of carbon oxides do not exceed the Jordanian standards of the ambient air and that the mathematical analysis indicators have pointed to the continuing increase of nitrogen oxides due to the increase of calm winds year after year. In fact, these winds do not help the dispersal and decrease of emissions; on the contrary, they increase the emissions concentration, especially in the areas approximate to the pollution sources.

  18. Coding and differential analysis of the problems of teenagers residing in protection centers in Spain

    Directory of Open Access Journals (Sweden)

    Juan Manuel Fernández-Millán

    2010-02-01

    Full Text Available Adolescence is a stage of life characterized by a marked and dififficult psysical, psychological and social development in which the young must face different daily problems and vital stressors. Knowing and classifying the conflicts that most worry the teenager might be used to direct the educative projects or therapeutic intervention more efficients. In this paper, problems perceived as more stressing have been codified and quantified through Adolescent’s Problems Differential Analysis and Coding System using a sample of minors leaving in a residential child care. A comparison betweenhoused teenagers and those who live with their parents show that housed minors (between 11 and 17 years old rise different vital situations in every single category. An outstanding fact is the high percentage of interpersonal problems with other house mates and related to sports and leisure time.

  19. A Review of Recent Aeroelastic Analysis Methods for Propulsion at NASA Lewis Research Center

    Science.gov (United States)

    Reddy, T. S. R.; Bakhle, Milind A.; Srivastava, R.; Mehmed, Oral; Stefko, George L.

    1993-01-01

    This report reviews aeroelastic analyses for propulsion components (propfans, compressors and turbines) being developed and used at NASA LeRC. These aeroelastic analyses include both structural and aerodynamic models. The structural models include a typical section, a beam (with and without disk flexibility), and a finite-element blade model (with plate bending elements). The aerodynamic models are based on the solution of equations ranging from the two-dimensional linear potential equation to the three-dimensional Euler equations for multibladed configurations. Typical calculated results are presented for each aeroelastic model. Suggestions for further research are made. Many of the currently available aeroelastic models and analysis methods are being incorporated in a unified computer program, APPLE (Aeroelasticity Program for Propulsion at LEwis).

  20. Risk factors for febrile urinary tract infection in infants with prenatal hydronephrosis: comprehensive single center analysis.

    Science.gov (United States)

    Zareba, Piotr; Lorenzo, Armando J; Braga, Luis H

    2014-05-01

    We assessed risk factors for urinary tract infection in children with prenatal hydronephrosis We identified 376 infants with prenatal hydronephrosis in an institutional database. The occurrence of febrile urinary tract infection in the first 2 years of life was ascertained by chart review. Febrile urinary tract infection was defined as a positive culture from a catheterized urine specimen in a patient with a fever of 38.0C or greater. Multivariate logistic regression was used to assess gender, circumcision status, hydronephrosis grade, vesicoureteral reflux grade and antibiotic prophylaxis as predictors of the risk of urinary tract infection. Included in analysis were 277 males and 99 females. Hydronephrosis was high grade in 128 infants (34.0%) and vesicoureteral reflux was present in 79 (21.0%). Antibiotic prophylaxis was prescribed in 60.4% of patients, preferentially to females vs males (70.7% vs 56.7%), those with high vs low grade hydronephrosis (70.3% vs 55.2%) and those with vs without vesicoureteral reflux (96.2% vs 50.8%). On multivariate analysis there was an association between high grade hydronephrosis and an increased risk of urinary tract infection (adjusted OR 2.40, 95% CI 1.26-4.56). Females (adjusted OR 3.16, 95% CI 0.98-10.19) and uncircumcised males (adjusted OR 3.63, 95% CI 1.18-11.22) were also at higher risk than circumcised males. Antibiotic prophylaxis was not associated with a decreased risk of urinary tract infection (adjusted OR 0.93, 95% CI 0.45-1.94). High grade hydronephrosis, female gender and uncircumcised status in males are independent risk factors for febrile urinary tract infection in infants with prenatal hydronephrosis. Antibiotic prophylaxis did not reduce the risk of urinary tract infection in the study group. Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  1. AN ANALYSIS OF THE MANUFACTURING PRODUCTIVITY WHEN THE SAME PIECE IS PERFORMED ON 3 VERSUS 4 AXES MACHINING CENTERS

    Directory of Open Access Journals (Sweden)

    Alexandru STANIMIR

    2012-05-01

    Full Text Available In this paper two technological manufacturing variants of a part are presented, one for fabrication on a vertical manufacturing centre with 3 axes YMC type and another one for fabrication on a horizontal manufacturing centre with 4 axes MCM type. The numerical control programs for the two manufacturing centers were made by using the CAD and CAM modules from the TopSolid software. The necessary times for doing the manufacturing were determined by their simulation, and by clocking the fabricating time of the products on the machines. After the analysis, there has been found for this case of study that, although there have been used the same cutting tools with the same cutting conditions, the higher number of fixings is not the most important factor for decreasing the productivity.

  2. Electronic health record usability: analysis of the user-centered design processes of eleven electronic health record vendors.

    Science.gov (United States)

    Ratwani, Raj M; Fairbanks, Rollin J; Hettinger, A Zachary; Benda, Natalie C

    2015-11-01

    The usability of electronic health records (EHRs) continues to be a point of dissatisfaction for providers, despite certification requirements from the Office of the National Coordinator that require EHR vendors to employ a user-centered design (UCD) process. To better understand factors that contribute to poor usability, a research team visited 11 different EHR vendors in order to analyze their UCD processes and discover the specific challenges that vendors faced as they sought to integrate UCD with their EHR development. Our analysis demonstrates a diverse range of vendors' UCD practices that fall into 3 categories: well-developed UCD, basic UCD, and misconceptions of UCD. Specific challenges to practicing UCD include conducting contextually rich studies of clinical workflow, recruiting participants for usability studies, and having support from leadership within the vendor organization. The results of the study provide novel insights for how to improve usability practices of EHR vendors.

  3. The Small Signal Analysis of a Centered Dielectric-Rod Loaded, Arbitrarily-Shaped Helical Groove Traveling-Wave-Tube

    Science.gov (United States)

    Wei, Yanyu; Liu, Hongtao; He, Jun; Gong, Yubin; Yue, Lingna; Wang, Wenxiang; Park, Gun-Sik

    2007-12-01

    Properties of traveling wave-beam interaction in a centered dielectric-rod loaded, arbitrarily-shaped helical groove slow-wave structure (SWS) are investigated for a thin annular electron beam. The “hot” dispersion equation is obtained by means of the self-consistent field theory, and the small signal analysis is carried out including the effects of the dielectric-rod parameters and the groove shapes. The numerical results show that the bandwidth of the helical groove TWT is expanded by loading dielectric-rod, however, the small-signal gain is reduced; and when the groove shape changes from the swallow-tail shape to the triangle shape, the working frequency increases , while the peak gain decreases.

  4. Correlation of site of embryo transfer with IVF outcome: Analysis of 743 cycles from a single center

    Directory of Open Access Journals (Sweden)

    Neeta Singh

    2017-01-01

    Full Text Available Objective: To investigate the influence of site of embryo transfer (ET on reproductive outcome. Materials and Methods: A retrospective analysis of 743 ultrasound-guided ET in fresh in vitro fertilization (IVF cycles from a single center over a period of 4 years was conducted. The distance between the fundal endometrial surface and the air bubble was measured, and accordingly, patients were divided into four groups (≤10 mm; >10 and ≤15 mm; >15 and 20 mm; >20 and 15 and <20 mm compared to less than 10-mm distance group. Ectopic pregnancy rates were similar in all the four groups. Conclusion: The present study demonstrates that site of ET has significant difference on reproductive outcome.

  5. Orbital Spectrum Analysis of Non-Axisymmetric Perturbations of the Guiding-Center Particle Motion in Axisymmetric Equilibria

    CERN Document Server

    Zestanakis, P A; Anastassiou, G; Hizanidis, K

    2015-01-01

    The presence of non-axisymmetric perturbations in an axisymmetric magnetic field equilibrium renders the Guiding Center (GC) particle motion non-integrable and may result in particle, energy and momentum redistribution, due to resonance mechanisms. We analyse these perturbations in terms of their spectrum, as observed by the particles in the frame of unperturbed GC motion. We calculate semi-analytically the exact locations and strength of resonant spectral components of multiple perturbations. The presented Orbital Spectrum Analysis (OSA) method is based on an exact Action-Angle transform that fully takes into account Finite Orbit Width (FOW) effects. The method provides insight into the particle dynamics and enables the prediction of the effect of any perturbation to all different types of particles and orbits in a given, analytically or numerically calculated, axisymmetric equilibrium.

  6. Ciguatera Fish Poisoning and Climate Change: Analysis of National Poison Center Data in the United States, 2001–2011

    Science.gov (United States)

    Strickland, Matthew J.; Hess, Jeremy J.

    2014-01-01

    Background: Warm sea surface temperatures (SSTs) are positively related to incidence of ciguatera fish poisoning (CFP). Increased severe storm frequency may create more habitat for ciguatoxic organisms. Although climate change could expand the endemic range of CFP, the relationship between CFP incidence and specific environmental conditions is unknown. Objectives: We estimated associations between monthly CFP incidence in the contiguous United States and SST and storm frequency in the Caribbean basin. Methods: We obtained information on 1,102 CFP-related calls to U.S. poison control centers during 2001–2011 from the National Poison Data System. We performed a time-series analysis using Poisson regression to relate monthly CFP call incidence to SST and tropical storms. We investigated associations across a range of plausible lag structures. Results: Results showed associations between monthly CFP calls and both warmer SSTs and increased tropical storm frequency. The SST variable with the strongest association linked current monthly CFP calls to the peak August SST of the previous year. The lag period with the strongest association for storms was 18 months. If climate change increases SST in the Caribbean 2.5–3.5°C over the coming century as projected, this model implies that CFP incidence in the United States is likely to increase 200–400%. Conclusions: Using CFP calls as a marker of CFP incidence, these results clarify associations between climate variability and CFP incidence and suggest that, all other things equal, climate change could increase the burden of CFP. These findings have implications for disease prediction, surveillance, and public health preparedness for climate change. Citation: Gingold DB, Strickland MJ, Hess JJ. 2014. Ciguatera fish poisoning and climate change: analysis of National Poison Center data in the United States, 2001–2011. Environ Health Perspect 122:580–586; http://dx.doi.org/10.1289/ehp.1307196 PMID:24618280

  7. Gastric leptomeningeal carcinomatosis: Multi-center retrospective analysis of 54 cases

    Institute of Scientific and Technical Information of China (English)

    Sung Yong Oh; Su-Jin Lee; Jeeyun Lee; Suee Lee; Sung-Hyun Kim; Hyuk-Chan Kwon; Gyeong-Won Lee; Jung Hun Kang; In Gyu Hwang; Joung-Soon Jang; Ho Yeong Lim; Young Suk Park; Won Ki Kang; Hyo-Jin Kim

    2009-01-01

    AIM: To identify the clinical features and outcomes of infrequently reported leptomeningeal carcinomatosis (LMC) of gastric cancer.METHODS: We analyzed 54 cases of cytologically con- firmed gastric LMC at four institutions from 1994 to 2007.RESULTS: The male-to-female ratio was 32:22, and the patients ranged in age from 28 to 78 years (median,48.5 years). The majority of patients had advanced disease at initial diagnosis of gastric cancer. The clinical or pathologic tumor, node and metastasis stage of the primary gastric cancer was Ⅳ in 38 patients (70%).The median interval from diagnosis of the primary malignancy to the diagnosis of LMC was 6.3 mo, ranging between 0 and 73.1 mo. Of the initial endoscopic findings for the 45 available patients, 23 (51%) of the patients were Bormann type Ⅲ and 15 (33%) patients were Bormann type Ⅳ. Pathologically, 94% of cases proved to be poorly differentiated adenocarcinomas.Signet ring cell component was also observed in 40% of patients. Headache (85%) and nausea/vomiting (58%) were the most common presenting symptoms of LMC. A gadolinium-enhanced magnetic resonance imaging was conducted in 51 patients. Leptomeningeal enhancement was noted in 45 cases (82%). Intrathecal (IT) chemotherapy was administered to 36 patientsprimarily methotrexate alone (61%), but also in combination with hydrocortisone/± Ara-C (39%). The median number of IT treatments was 7 (range, 1-18). Concomitant radiotherapy was administered to 18 patients,and concomitant chemotherapy to seven patients. Seventeen patients (46%) achieved cytological negative conversion. Median overall survival duration from the diagnosis of LMC was 6.7 wk (95% CI: 4.3-9.1 wk). In the univariate analysis of survival duration, hemoglobin,IT chemotherapy, and cytological negative conversion showed superior survival duration ( P = 0.038, P = 0.010, and P = 0.002, respectively). However, in our multivariate analysis, only cytological negative conversion was predictive of

  8. The IEO Data Center Management System: Tools for quality control, analysis and access marine data

    Science.gov (United States)

    Casas, Antonia; Garcia, Maria Jesus; Nikouline, Andrei

    2010-05-01

    Since 1994 the Data Centre of the Spanish Oceanographic Institute develops system for archiving and quality control of oceanographic data. The work started in the frame of the European Marine Science & Technology Programme (MAST) when a consortium of several Mediterranean Data Centres began to work on the MEDATLAS project. Along the years, old software modules for MS DOS were rewritten, improved and migrated to Windows environment. Oceanographic data quality control includes now not only vertical profiles (mainly CTD and bottles observations) but also time series of currents and sea level observations. New powerful routines for analysis and for graphic visualization were added. Data presented originally in ASCII format were organized recently in an open source MySQL database. Nowadays, the IEO, as part of SeaDataNet Infrastructure, has designed and developed a new information system, consistent with the ISO 19115 and SeaDataNet standards, in order to manage the large and diverse marine data and information originated in Spain by different sources, and to interoperate with SeaDataNet. The system works with data stored in ASCII files (MEDATLAS, ODV) as well as data stored within the relational database. The components of the system are: 1.MEDATLAS Format and Quality Control - QCDAMAR: Quality Control of Marine Data. Main set of tools for working with data presented as text files. Includes extended quality control (searching for duplicated cruises and profiles, checking date, position, ship velocity, constant profiles, spikes, density inversion, sounding, acceptable data, impossible regional values,...) and input/output filters. - QCMareas: A set of procedures for the quality control of tide gauge data according to standard international Sea Level Observing System. These procedures include checking for unexpected anomalies in the time series, interpolation, filtering, computation of basic statistics and residuals. 2. DAMAR: A relational data base (MySql) designed to

  9. The American Climate Prospectus: a risk-centered analysis of the economic impacts of climate change

    Science.gov (United States)

    Jina, A.; Houser, T.; Hsiang, S. M.; Kopp, R. E., III; Delgado, M.; Larsen, K.; Mohan, S.; Rasmussen, D.; Rising, J.; Wilson, P. S.; Muir-Wood, R.

    2014-12-01

    The American Climate Prospectus (ACP), the analysis underlying the Risky Business project, quantitatively assessed the climate risks posed to the United States' economy in six sectors - crop yields, energy demand, coastal property, crime, labor productivity, and mortality [1]. The ACP is unique in its characterization of the full probability distribution of economic impacts of climate change throughout the 21st century, making it an extremely useful basis for risk assessments. Three key innovations allow for this characterization. First, climate projections from CMIP5 models are scaled to a temperature probability distribution derived from a coarser climate model (MAGICC). This allows a more accurate representation of the whole distribution of future climates (in particular the tails) than a simple ensemble average. These are downscaled both temporally and spatially. Second, a set of local sea level rise and tropical cyclone projections are used in conjunction with the most detailed dataset of coastal property in the US in order to capture the risks of rising seas and storm surge. Third, we base many of our sectors on empirically-derived responses to temperature and precipitation. Each of these dose-response functions is resampled many times to populate a statistical distribution. Combining these with uncertainty in emissions scenario, climate model, and weather, we create the full probability distribution of climate impacts from county up to national levels, as well as model the effects upon the economy as a whole. Results are presented as likelihood ranges, as well as changes to return intervals of extreme events. The ACP analysis allows us to compare between sectors to understand the magnitude of required policy responses, and also to identify risks through time. Many sectors displaying large impacts at the end of the century, like those of mortality, have smaller changes in the near-term, due to non-linearities in the response functions. Other sectors, like

  10. Lymphocytes as an Indicator for Initial Kidney Function: A Single Center Analysis of Outcome after Alemtuzumab or Basiliximab Induction

    Directory of Open Access Journals (Sweden)

    Annemarie Weissenbacher

    2015-01-01

    Full Text Available Alemtuzumab, an anti-CD52 T-cell and B-cell depleting monoclonal antibody, is established for induction therapy in renal transplantation (KTx. We herein provide a comparative analysis between alemtuzumab and basiliximab induction therapy and correlate lymphocyte depletion and recovery with the clinical course after KTx. This is a single center retrospective analysis of 225 patients/consecutive kidney transplantations treated with alemtuzumab for lymphocyte depletion and 205 recipients treated with basiliximab. Mean lymphocyte counts were 22.8 ± 9.41% before Tx and 2.61 ± 3.11% between week 1 and week 3 in the alemtuzumab group and 23.77 ± 10.42% before Tx and 13.92 ± 8.20% in the basiliximab group. Delayed graft function (DGF, cytomegalovirus (CMV status, and recipient age showed a significant correlation with lymphocyte counts in the alemtuzumab group only. The outcome was read in reference to the velocity of lymphocyte recovery and in comparison to the control group. Lymphocyte counts early after transplantation, following alemtuzumab treatment, could be identified as a predictive factor for kidney function early after transplantation. A detailed analysis of phenotype and function of lymphocytes after alemtuzumab induction together with a correlation with the clinical course is warranted.

  11. Lymphocytes as an Indicator for Initial Kidney Function: A Single Center Analysis of Outcome after Alemtuzumab or Basiliximab Induction.

    Science.gov (United States)

    Weissenbacher, Annemarie; Hautz, Theresa; Kimelman, Michael; Oberhuber, Rupert; Ulmer, Hanno; Bösmüller, Claudia; Maglione, Manuel; Schneeberger, Stefan

    2015-01-01

    Alemtuzumab, an anti-CD52 T-cell and B-cell depleting monoclonal antibody, is established for induction therapy in renal transplantation (KTx). We herein provide a comparative analysis between alemtuzumab and basiliximab induction therapy and correlate lymphocyte depletion and recovery with the clinical course after KTx. This is a single center retrospective analysis of 225 patients/consecutive kidney transplantations treated with alemtuzumab for lymphocyte depletion and 205 recipients treated with basiliximab. Mean lymphocyte counts were 22.8 ± 9.41% before Tx and 2.61 ± 3.11% between week 1 and week 3 in the alemtuzumab group and 23.77 ± 10.42% before Tx and 13.92 ± 8.20% in the basiliximab group. Delayed graft function (DGF), cytomegalovirus (CMV) status, and recipient age showed a significant correlation with lymphocyte counts in the alemtuzumab group only. The outcome was read in reference to the velocity of lymphocyte recovery and in comparison to the control group. Lymphocyte counts early after transplantation, following alemtuzumab treatment, could be identified as a predictive factor for kidney function early after transplantation. A detailed analysis of phenotype and function of lymphocytes after alemtuzumab induction together with a correlation with the clinical course is warranted.

  12. Thrombophilia diagnosis: a retrospective analysis of a single-center experience.

    Science.gov (United States)

    Spychalska-Zwolińska, Marta; Zwoliński, Tomasz; Mieczkowski, Artur; Budzyński, Jacek

    2015-09-01

    It is estimated that 30-50% of patients suffering from deep vein thrombosis (DVT) could be diagnosed with congenital or acquired thrombophilia. Its diagnosis, however, rarely changes the clinical management, but is associated with significant costs and negative psychological and social aspects. The aim of this study was to perform a retrospective analysis of the causes and clinical consequences of diagnostics for thrombophilia. A retrospective review of the medical records of 5600 patients was performed, 62 of whom had, at the time, been diagnosed for thrombophilia because of a thromboembolic event. A review of the current literature on the validity of diagnostic tests for hypercoagulability in certain clinical conditions was also performed. The most common reason for thrombophilia testing was episodes of lower limb DVT (56%). The most frequently diagnosed abnormalities were the heterozygous form of the V Leiden gene (18%), protein S deficiency (11%), and the anti cardiolipin antibody IgG (11%). In 45% of the patients, laboratory results did not confirm the presence of any congenital thrombophilia. After receiving the results, 11% of the respondents completed oral anticoagulation therapy after 3 months, and 28% of patients qualified for indefinite use of oral anticoagulant therapy. In most of the cases examined, the diagnosis of thrombophilia did not significantly affect the treatment. A common aberration identified in patients with a history of thromboembolic incidents was the coexistence of risk factors for atherosclerosis.

  13. A Person-Centered Analysis of Risk Factors that Compromise Wellbeing in Emerging Adulthood.

    Science.gov (United States)

    Newcomb-Anjo, Sarah E; Barker, Erin T; Howard, Andrea L

    2016-11-08

    The transition to adulthood is a major life course transition that can pose risk to wellbeing. Research is needed to identify patterns of risk for compromised wellbeing, in order to best identify supports for individuals during this potentially vulnerable transition. The purpose of this study was to identify profiles of risk in an emerging adulthood sample, and to relate these profiles to mental health and subjective and academic wellbeing. Undergraduate emerging adults (N = 903, 82 % female), aged 18-25 years (M = 21.14, SD = 1.75), completed a series of questionnaires about risk factors, mental health, and academic variables. Results from a latent profile analysis identified four distinct risk profiles: Low Risk (76 %), Low Social Support Risk (4 %), Financial Risk (11 %), and Multiple Risk (8 %). The risk profiles were subsequently related to mental health and subjective and academic wellbeing outcomes, using a pseudo-class draws approach. Analyses indicated that the risk-pattern profiles differed in several ways across outcomes. Implications for targeted interventions are discussed.

  14. Computer Data Analysis for Meteorology - Project-Centered Skill Development for the Early Undergraduate Career

    Science.gov (United States)

    Ellis, T. D.

    2014-12-01

    Too often in geoscience education are the computer skills necessary for success in the workforce put off until the last years of undergraduate education. This is especially true in meteorology, a form of geophysical fluid dynamics many people encounter on a daily basis. Meteorologists often need to know specialized computer skills, including the use of scripting languages to automate handling large bundles of data, manipulating four-dimensional arrays (with three spatial dimensions and one time dimension), visualizing said datasets simply and effectively for publication, and performing statistical analysis of those datasets. Such topics are often addressed only at the senior undergraduate level or graduate school. At SUNY Oneonta, we are piloting a course that teaches these skills to third-semester students with the intent of building confidence in these skills throughout students' careers and with the of building a tool-box of skills that can be used in upper-division courses and undergraduate research. This poster will present the methods used in building this course, the kinds of activities designed, the desired student learning outcomes, and our assessment of those outcomes, and new initiatives engaged since the completion of the NSF-funded portion of the project in 2012.

  15. Examining the relationship between social support availability, urban center size, and self-perceived mental health of recent immigrants to Canada: a mixed-methods analysis.

    Science.gov (United States)

    Chadwick, Kathryn A; Collins, Patricia A

    2015-03-01

    The experiences of settlement in a new country (e.g., securing housing and employment, language barriers) pose numerous challenges for recent immigrants that can impede their health and well-being. Lack of social support upon arrival and during settlement may help to explain why immigrant mental health status declines over time. While most urban centers in Canada offer some settlement services, little is known about how the availability of social supports, and the health statuses of recent immigrants, varies by city size. The objective of this mixed-methods study was to examine the relationship between self-perceived mental health (SPMH), social support availability, and urban center size, for recent immigrants to Canada. The quantitative component involved analysis of 2009-2010 Canadian Community Health Survey data, selecting for only recent immigrants and for those living in either large or small urban centers. The qualitative component involved in-depth interviews with managers of settlement service organizations located in three large and three small urban centers in Canada. The quantitative analysis revealed that social support availability is positively associated with higher SPMH status, and is higher in small urban centers. In support of these findings, our interviews revealed that settlement service organizations operating in small urban centers offer more intensive social supports; interviewees attributed this difference to personal relationships in small cities, and the ease with which they can connect to other agencies to provide clients with necessary supports. Logistic regression analysis revealed, however, that recent immigrants in small urban centers are twice as likely to report low SPMH compared to those living in large urban centers. Thus, while the scope and nature of settlements services appears to vary by city size in Canada, more research is needed to understand what effect settlement services have on the health status of recent immigrants to

  16. Analysis of the treatment outcomes of esophageal variceal bleeding patients from multiple centers in China

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This study aimed to investigate the treatment outcomes of esophageal variceal bleeding(EVB)in China.A total of 1087 cases were collected from 19 hospitals in 16 large and medium sized cities across China between January 1st,2005 and January 1st,2006.There were 313 cases(29.0%)of mild(<400 mL),494 cases(45.8%)of moderate(400-1500 mL)and 272 cases(25.2%)of severe (>1500 mL)bleeding.Successful hemostasis was achieved in 89.8% of cases.Seven hundred and eighty-five cases were treated by medication with a hemostasis rate of 91.8%.Seventy-one cases were treated using a SengstakenBlakemore tube with a hemostasis rate of 54.9%.Thirtyseven cases were treated with emergency endoscopic variceal ligation with a hemostasis rate of 83.8%.Seventyseven cases were treated with endoscopic sclerotherapy with a hemostasis rate of 94.8%.Forty-three cases were treated with emergency surgical operation with a hemostasis rate of 95.3%.Sixty-six cases were treated with combined therapy with a hemostasis rate of 97.0%.There was a significant difference(P<0.01)in the successful hemostasis rate between different treatments.The overall mortality was 10.1%,among which 6.6% was directly caused by bleeding.The multivariate logistic regression analysis shows that the severity of bleeding,treatment methods,liver dysfunction and activation of hepatitis were predictive factors for successful hemostasis.Most cases of EVB were mild and moderate in severity.The first-line treatment for EVB is medication.Emergency endoscopic intervention has not been widely available yet.The overall management outcome of EVB has been improved.

  17. Predicting patients that require care at a trauma center: analysis of injuries and other factors.

    Science.gov (United States)

    Schoell, Samantha L; Doud, Andrea N; Weaver, Ashley A; Barnard, Ryan T; Meredith, J Wayne; Stitzel, Joel D; Martin, R Shayn

    2015-04-01

    The detection of occult or unpredictable injuries in motor vehicle crashes (MVCs) is crucial in correctly triaging patients and thus reducing fatalities. The purpose of the study was to develop a metric that indicates the likelihood that an injury sustained in a MVC would require management at a Level I/II trauma centre (TC) versus a non-trauma centre (non-TC). Transfer Scores (TSs) were computed for 240 injuries that comprise the top 95% most frequently occurring injuries in the National Automotive Sampling System-Crashworthiness Data System (NASS-CDS) with an Abbreviated Injury Scale (AIS) severity of 2 or greater. A TS for each injury was computed using the proportions of patients involved in a MVC from the National Inpatient Sample (NIS) that were transferred to a TC or managed at a non-TC. Similarly, a TSMAIS that excludes patients with higher severity co-injuries was calculated using the proportion of patients with a maximum AIS (MAIS) equal to the AIS severity of a given injury. The results indicated for injuries of a given AIS severity, body region, and injury type, there were large variations in the TSMAIS. Overall results demonstrated higher TSMAIS values when injuries were internal, haemorrhagic, intracranial or of moderate severity (AIS 3-5). Specifically, injuries to the head possessed a TSMAIS that ranged from 0.000 to 0.889, with head injuries of AIS 3-5 severities being the most likely to be transferred. The analysis indicated that the TSMAIS is not solely correlated with AIS severity and therefore it captures other important aspects of injury such as predictability and trauma system capabilities. The TS and TSMAIS can be useful in advanced automatic crash notification (AACN) research for the detection of highly unpredictable injuries in MVCs that require direct transport to a TC. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Analysis of 300 consecutive cases of pancreatic adenocarcinoma in a single-center in China

    Institute of Scientific and Technical Information of China (English)

    Han Lin; Yong Ma; Ji-Zhou Wang; Hua-Yang Pan; Lian-Xin Liu; Hai-Quan Qiao; Bei Sun; Hong-Chi Jiang

    2016-01-01

    BACKGROUND: Most of the reports on the prognostic indi-cators of patients with pancreatic adenocarcinoma are from developed countries. The present study focused on the prog-nostic indicators of Chinese patients with pancreatic adeno-carcinoma. METHODS: A total of 300 patients with pancreatic adenocar-cinoma who had undergone curative resection were included. The resection and R0/R1 resection rates for adenocarcinomas from different parts of the pancreas were calculated and clini-cal characteristics were analyzed. RESULTS: In 3427 patients diagnosed with pancreatic adeno-carcinomas, only 300 (8.8%) were eligible for radical resection. The total median survival of these patients was 19 months, and their 1-, 3-, and 5-year survival rates were 72.5%, 28.0%and 23.4%, respectively. The prognostic factors included so-cioeconomic status, smoking history, symptoms, high blood glucose, and various tumor characteristics, including perineu-ral and vascular invasion, lymph node metastases, and CA19-9 levels before and after operation. Operation-associated prog-nostic indicators included operation time, blood loss and transfusions, pancreatic ifstula, and complications. Indepen-dent predictors of mortality included poor socioeconomic sta-tus, smoking history, symptoms, CA19-9, perineural invasion and lymph node metastasis, grade of ifstula and complications. Patient survival was not correlated with either resection mar-gin or adjuvant chemotherapy in multivariate analysis. CONCLUSIONS: The survival rates of patients with curative resection for pancreatic adenocarcinoma in China are close to those in developed countries, but curative resection rate is far below. Socioeconomic status, symptoms, and CA19-9 are the three most prominent prognostic factors, which are helpful in patient selection and perioperative care.

  19. Kennedy Space Center (KSC) Pad B Catenary Capability Analysis and Technical Exchange Meeting (TEM) Support

    Science.gov (United States)

    Wilson, Timmy R.; Kichak, Robert; Rakov, Vladimir; Kithil, Richard, Jr.; Sargent, Noel B.

    2009-01-01

    The existing lightning protection system at Pad 39B for the Space Shuttle is an outgrowth of a system that was put in place for the Apollo Program. Dr. Frank Fisher of Lightning Technologies was a key participant in the design and implementation of that system. He conveyed to the NESC team that the catenary wire provision was put in place quickly (as assurance against possible vehicle damage causing critical launch delays) rather than being implemented as a comprehensive system designed to provide a high degree of guaranteed protection. Also, the technology of lightning protection has evolved over time with considerable work being conducted by groups such as the electric utilities companies, aircraft manufacturers, universities, and others. Several accepted present-day methods for analysis of lightning protection were used by Drs. Medelius and Mata to study the expected lightning environment for the Pad 39B facility and to analyze the degree of protection against direct lightning attachment to the Space Shuttle. The specific physical configuration directly affects the vulnerability, so cases that were considered included the RSS next to and rolled back from the Space Shuttle, and the GOx Vent Arm both extended and withdrawn from the ET. Elements of the lightning protection system at Pad 39B are shown in Figure 6.0-1 and consist of an 80 foot insulating mast on top of the Fixed Support Structure (FSS), a catenary wire system that runs from the mast in a North/South direction to grounds 1000 feet away on each side of the mast, the RSS which can either be next to or away from the Space Shuttle, and a GOx vent that can either be extended or retracted from the top of the ET.

  20. Data Center at NICT

    Science.gov (United States)

    Ichikawa, Ryuichi; Sekido, Mamoru

    2013-01-01

    The Data Center at the National Institute of Information and Communications Technology (NICT) archives and releases the databases and analysis results processed at the Correlator and the Analysis Center at NICT. Regular VLBI sessions of the Key Stone Project VLBI Network were the primary objective of the Data Center. These regular sessions continued until the end of November 2001. In addition to the Key Stone Project VLBI sessions, NICT has been conducting geodetic VLBI sessions for various purposes, and these data are also archived and released by the Data Center.

  1. MODAL ANALYSIS OF CARRIER SYSTEM FOR HEAVY HORIZONTAL MULTIFUNCTION MACHINING CENTER BY FINITE ELEMENT METHOD

    Directory of Open Access Journals (Sweden)

    Yu. V. Vasilevich

    2014-01-01

    Full Text Available The aim of the paper is to reveal and analyze resonance modes of a large-scale milling-drilling-boring machine. The machine has a movable column with vertical slot occupied by a symmetrical carriage with horizontal ram. Static rigidity of the machine is relatively low due to its large dimensions. So it is necessary to assess possible vibration activity. Virtual and operational trials of the machine have been carried out simultaneously. Modeling has been executed with the help of a finite element method (FEM. The FEM-model takes into account not only rigidity of machine structures but also flexibility of bearings, feed drive systems and guides. Modal FEM-analysis has revealed eight resonance modes that embrace the whole machine tool. They form a frequency interval from 12 to 75 Hz which is undesirable for machining. Three closely located resonances (31-37 Hz are considered as the most dangerous ones. They represent various combinations of three simple motions: vertical oscillations of a carriage, horizontal vibrations of a ram and column torsion. Reliability of FEM- estimations has been proved by in-situ vibration measurements.An effect for stabilization of resonance modes has been detected while making variations in design parameters of the machine tool. For example, a virtual replacement of cast iron for steel in machine structures practically does not have any effect on resonance frequencies. Rigidity increase in some parts (e.g. a ram has also a small effect on a resonance pattern. On the other hand, resonance stability makes it possible to avoid them while selecting a spindle rotation frequency.It is recommended to set double feed drives for all axes. A pair of vertical screws prevents a “pecking” resonance of the carriage at frequency of 54 Hz. It is necessary to foresee an operation of a main drive of such heavy machine tool in the above resonance interval with the spindle frequency of more than 75 Hz. For this purpose it is necessary

  2. Excel Center

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Citigroup,one of the World top 500 companies,has now settled in Excel Center,Financial Street. The opening ceremony of Excel Center and the entry ceremony of Citigroup in the center were held on March 31.Government leaders of Xicheng District,the Excel CEO and the heads of Asia-Pacific Region leaders of Citibank all participated in the ceremony.

  3. The analysis of perinatal morbidity and mortality in conditions of perinatal center and the ways of its decrease

    Directory of Open Access Journals (Sweden)

    Нана Мерабівна Пасієшвілі

    2016-01-01

    Full Text Available Aim of research. The analysis of perinatal morbidity and mortality in the condition of one perinatal center of Ukraine and optimization of the possible ways of its decrease.Methods of research. There was analyze the work of Kharkiv regional center in 2011–2015 years taking into account the rates of perinatal morbidity and mortality and factors that have influence on it. There were studied the next parameters: the number of newborns, its apportionment on the weight category, survival, general morbidity, mortality structure of the full-term and premature children. Statistical processing of the received results was carried out using Statistica 6.0 program.Results of research. The frequency of normal delivery in perinatal center is in average 58,9 %. The rates of neonatal mortality decreased– 4,11 ‰ (in 2011 year – 8,23 ‰ and early neonatal one – 3,34 ‰ (in 2011 year – 6,44 ‰. The survival of newborns with extremely low body weight (500- 999 g in first 0-168 hours was 62,50 %; with body weight 1000 – 1499 g – 82,35 %; with body weight at delivery 1500-2499 g was 98,17 %, survival of newborns with body weight > 2500 g in the first 0-6 days was 99,75 % .The morbidity structure of full-term children still almost unchangeable during the last 5 years: asphyxia, congenital defects of development, arrest of foetus growth, cerebral ischemia, intrauterine infection, birth trauma. The morbidity structure of premature ones: respiratory disorder syndrome, intrauterine infection; asphyxia, congenital defects of development, arrest of foetus growth.Among the mortality causes the main ones were congenial defects of development (prevailed in full-term children and intrauterine infection (on the first place in premature children. The perinatal mortality rate in 2015 year was 18,22 %о, in 2011year – 26,65 %о . The maternal foetus infection is the very frequent cause of stillbirth and pre-term birth and as the result the birth of small

  4. Reliability of recurrence quantification analysis measures of the center of pressure during standing in individuals with musculoskeletal disorders.

    Science.gov (United States)

    Mazaheri, Masood; Negahban, Hossein; Salavati, Mahyar; Sanjari, Mohammad Ali; Parnianpour, Mohamad

    2010-09-01

    Although the application of nonlinear tools including recurrence quantification analysis (RQA) has increasingly grown in the recent years especially in balance-disordered populations, there have been few studies which determine their measurement properties. Therefore, a methodological study was performed to estimate the intersession and intrasession reliability of some dynamic features provided by RQA for nonlinear analysis of center of pressure (COP) signals recorded during quiet standing in a sample of patients with musculoskeletal disorders (MSDs) including low back pain (LBP), anterior cruciate ligament (ACL) injury and functional ankle instability (FAI). The subjects completed postural measurements with three levels of difficulty (rigid surface-eyes open, rigid surface-eyes closed, and foam surface-eyes closed). Four RQA measures (% recurrence, % determinism, entropy, and trend) were extracted from the recurrence plot. Relative reliability of these measures was assessed using intraclass correlation coefficient and absolute reliability using standard error of measurement and coefficient of variation. % Determinism and entropy were the most reliable features of RQA for the both intersession and intrasession reliability measures. High level of reliability of % determinism and entropy in this preliminary investigation may show their clinical promise for discriminative and evaluative purposes of balance performance.

  5. NASA Johnson Space Center's Planetary Sample Analysis and Mission Science (PSAMS) Laboratory: A National Facility for Planetary Research

    Science.gov (United States)

    Draper, D. S.

    2016-01-01

    NASA Johnson Space Center's (JSC's) Astromaterials Research and Exploration Science (ARES) Division, part of the Exploration Integration and Science Directorate, houses a unique combination of laboratories and other assets for conducting cutting edge planetary research. These facilities have been accessed for decades by outside scientists, most at no cost and on an informal basis. ARES has thus provided substantial leverage to many past and ongoing science projects at the national and international level. Here we propose to formalize that support via an ARES/JSC Plane-tary Sample Analysis and Mission Science Laboratory (PSAMS Lab). We maintain three major research capa-bilities: astromaterial sample analysis, planetary process simulation, and robotic-mission analog research. ARES scientists also support planning for eventual human ex-ploration missions, including astronaut geological training. We outline our facility's capabilities and its potential service to the community at large which, taken together with longstanding ARES experience and expertise in curation and in applied mission science, enable multi-disciplinary planetary research possible at no other institution. Comprehensive campaigns incorporating sample data, experimental constraints, and mission science data can be conducted under one roof.

  6. Spatial synchronization of an insole pressure distribution system with a 3D motion analysis system for center of pressure measurements.

    Science.gov (United States)

    Fradet, Laetitia; Siegel, Johannes; Dahl, Marieke; Alimusaj, Merkur; Wolf, Sebastian I

    2009-01-01

    Insole pressure systems are often more appropriate than force platforms for analysing center of pressure (CoP) as they are more flexible in use and indicate the position of the CoP that characterizes the contact foot/shoe during gait with shoes. However, these systems are typically not synchronized with 3D motion analysis systems. The present paper proposes a direct method that does not require a force platform for synchronizing an insole pressure system with a 3D motion analysis system. The distance separating 24 different CoPs measured optically and their equivalents measured by the insoles and transformed in the global coordinate system did not exceed 2 mm, confirming the suitability of the method proposed. Additionally, during static single limb stance, distances smaller than 7 mm and correlations higher than 0.94 were found between CoP trajectories measured with insoles and force platforms. Similar measurements were performed during gait to illustrate the characteristics of the CoP measured with each system. The distance separating the two CoPs was below 19 mm and the coefficient of correlation above 0.86. The proposed method offers the possibility to conduct new experiments, such as the investigation of proprioception in climbing stairs or in the presence of obstacles.

  7. The Collaborative Production of Responses and Dispatching on the Radio: Video Analysis in a Medical Emergency Call Center

    Directory of Open Access Journals (Sweden)

    Giolo Fele

    2008-10-01

    Full Text Available What happens when someone rings an emergency hotline for help? How is the emergency handled? How does the emergency service swing into action? Prompt and competent intervention and assessment of the gravity of the situation in a few crucial seconds: these are the quality standards that regulate the organization of emergency operations centers. For a number of years various groups of social science researchers have carried forward a program for the systematic study of work using ethnographic and naturalistic methods of analysis. An interest in work is certainly nothing new in the social sciences, and in sociology in particular. What is new, though, is the particular analytical viewpoint from which such research is now conducted. This program has dispensed with large-scale theorization and has concentrated on the empirical study of activities and practices, achieving an unprecedented level of detail and analytical fineness. Indeed, only by proceeding at this fine level of detail—made possible by the use of videorecordings—has it been possible to document the extraordinary and subtle collaborative production of work, and to do so at a level which extends well beyond the conscious awareness of people in their everyday routine. This aspect concerns in particular the capacity of the latest generation of studies of work to document the tacit procedures and forms of common-sense reasoning involved in the performance of tasks in concrete work settings. This paper focuses on the ways in which the dispatch is done in a medical emergency operation center. Although we know a great deal about the interaction between caller and call-taker from previous research, we know much less about the social organization that makes the dispatch possible. The data analyzed in this paper derive from a research project in which I have been engaged for a number of years on operation centers for the 118 emergency telephone number in Italy. Contrasting the data obtained

  8. The Academic Medical Center Linear Disability Score (ALDS) item bank: item response theory analysis in a mixed patient population.

    Science.gov (United States)

    Holman, Rebecca; Weisscher, Nadine; Glas, Cees A W; Dijkgraaf, Marcel G W; Vermeulen, Marinus; de Haan, Rob J; Lindeboom, Robert

    2005-12-29

    Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55%) residents of supported housing, residential care or nursing homes; 235 (23%) patients with chronic pain; 127 (13%) inpatients on a neurology ward following a stroke; and 89 (9%) patients suffering from Parkinson's disease. Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations.

  9. The Academic Medical Center Linear Disability Score (ALDS) item bank: item response theory analysis in a mixed patient population

    Science.gov (United States)

    Holman, Rebecca; Weisscher, Nadine; Glas, Cees AW; Dijkgraaf, Marcel GW; Vermeulen, Marinus; de Haan, Rob J; Lindeboom, Robert

    2005-01-01

    Background Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. Methods This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55%) residents of supported housing, residential care or nursing homes; 235 (23%) patients with chronic pain; 127 (13%) inpatients on a neurology ward following a stroke; and 89 (9%) patients suffering from Parkinson's disease. Results Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. Conclusion The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations. PMID:16381611

  10. The Academic Medical Center Linear Disability Score (ALDS item bank: item response theory analysis in a mixed patient population

    Directory of Open Access Journals (Sweden)

    Vermeulen Marinus

    2005-12-01

    Full Text Available Abstract Background Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. Methods This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55% residents of supported housing, residential care or nursing homes; 235 (23% patients with chronic pain; 127 (13% inpatients on a neurology ward following a stroke; and 89 (9% patients suffering from Parkinson's disease. Results Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. Conclusion The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations.

  11. Analysis of weight and associated health consequences of the active duty staff at a major Naval medical center.

    Science.gov (United States)

    Gantt, Cynthia J; Neely, Julie A; Villafana, Ian A; Chun, Chisun S; Gharabaghli, Sandy M

    2008-05-01

    The purpose of this study was to analyze the prevalence of overweight and obesity among active duty staff members at one the Navy's largest medical centers, in an effort to clarify the relationship between weight, physical fitness, health care utilization patterns, and health care costs. Data obtained from the Physical Readiness Information Management System were linked with health care utilization data obtained from the Military Health System Management Analysis and Reporting Tool. This information was applied to the National Heart, Lung, and Blood Institute risk-stratification criteria to clarify the roles overweight and obesity play as factors contributing to increased health risk, comorbid conditions, and health care costs in this military health care setting. At least 53% of the active duty staff members (1,755 of 3,306) at this medical center were either overweight or obese, based on body mass index (BMI). Three hundred fifty-one personnel did not have body composition analyses recorded. Using the Navy's current system, only 149 personnel were identified as being "out of standards" and 2,806 personnel were considered to be "within standards." Remarkably, the within-standards group included 241 personnel with obese BMIs and 1,365 personnel with overweight BMIs. The National Heart, Lung, and Blood Institute risk-stratification criteria identified 445 personnel as having increased risk of premature death, based on their BMIs and other risk factors. The Navy's current program resulted in 296 (445 minus 149) missed opportunities to provide weight loss intervention when it is most effective, in the early stages of weight gain. The system currently used by the U.S. Navy to characterize personnel by weight ignores opportunities to identify and to treat high-risk personnel and provides neither a consistent nor an evidence-based model for early intervention and treatment of high-weight personnel at risk for increased morbidity, loss of productivity, and associated

  12. The Evaluation and Improvement of Microbial Analysis Methods and Techniques in the Johnson Space Center Microbiology Laboratory

    Science.gov (United States)

    St. Pierre, Ashley L.; Smith, Melanie J.; Dunbar, Brandon J.; Ott, C. Mark

    2016-01-01

    Microbial contamination is a risk to crew health both on the ground and on the International Space Station. The methods and techniques of microbial analysis for surfaces and items on board a spacecraft are an important aspect of ensuring that crew health is not at unnecessary risk. This series of projects seeks to improve and optimize microbial analysis methods, such as the recovery of bacteria from difficult surfaces, and the analysis of long-term bacterial isolate storage techniques. These projects will help the Johnson Space Center Microbiology laboratory be more efficient at identifying and addressing microbial concerns related to spaceflight and on the ground. Fabrics are substantially more problematic for microbial monitoring than steel or glass surfaces, as bacteria tend to get trapped in the fibers. To better understand which microbial sampling method is most efficient, various methods of recovery were attempted, and the processes were revised based on the results. The final phase of testing applied the knowledge gained from the resulting methods to an acoustic blanket that is currently being used on the International Space Station, with future use slated for the Orion spacecraft. In this phase, the sample materials were inoculated with bacterial suspensions, vortexed with phosphate-saline buffer, and the liquid was plated on tryptic soy agar. The results from the test of the acoustic blanket indicate that not only is microbial growth possible on fabric that is treated for moisture-resistance, but also that contamination can occur if aseptic handling procedures are not followed. Interestingly, out of three hundred and ninety (390) plates, only seventeen (17) showed growth (4.36%), and recovery of the Staphylococcus epidermidis used to inoculate the samples only occurred on four (4) of the plates. The growth on the remaining plates was contamination by various microbes, including those commonly found on the skin and in soil. This shows that 2 while bacterial

  13. Epidemiologic characteristics of oral cancer:single-center analysis of 4097 patients from the Sun Yat-sen University Cancer Center

    Institute of Scientific and Technical Information of China (English)

    Ji Zhang; Ming Song; Fan Gao; AnKui Yang; WenKuan Chen; ShuWei Chen; Huan Li; Xing Zhang; ZhongYuan Yang; XinLin Chen

    2016-01-01

    Background: Oral cancer is a common type of head and neck cancers. Knowing its epidemiologic characteristics is crucial to preventing, diagnosing, and treating this cancer. This study aimed to explore the epidemiologic characteris‑tics of oral cancer in South China. Methods: We retrospectively analyzed data from 4097 oral cancer patients treated at the Sun Yat‑sen University Cancer Center between 1960 and 2013. We compared the age of onset, sex ratio, pathologic type, and primary tumor location among three subcultural areas (Guangfu, Hakka, and Chaoshan) and between an economically developed region and a less‑developed one in Guangdong. Results: Overall, oral cancer had a male‑to‑female ratio of approximately 2:1, and this ratio decreased over time. Oral cancer occurred mostly in patients of 45–64 years old (54.5%), and the percentage of older patients gradually increased over time. The most common tumor location was the tongue. Squamous cell carcinoma was the predomi‑nant pathologic type. The percentage of blood type O in oral cancer patients was lower than that in the healthy pop‑ulation. The male‑to‑female ratio in the Chaoshan area was higher than that in the Guangfu and Hakka areas, whereas the age of disease onset in Guangfu was higher than that in Hakka and Chaoshan. The male‑to‑female ratio was lower and the age of disease onset was higher in the economically developed region than in the less‑developed region. Conclusion: The incidence of oral cancer in South China presents typical characteristics to which doctors should pay attention when diagnosing and treating oral cancer patients.

  14. Solar Data Analysis Center

    Data.gov (United States)

    National Aeronautics and Space Administration — The Yohkoh Legacy data Archive (YLA) is intended to provide all usable scientific data obtained with the Yohkoh satellite, in convenient forms for research and...

  15. Seismic Data Analysis Center

    Science.gov (United States)

    1983-01-10

    command now logs each invocation to maintain audit trails of its use, "print" the set of programs dealing with line printors and spooling were recompiled...damaged file systems, " pfe " - installed to examine a core dump of a user program to determine what kind of floating exception (overflow, underflow

  16. Does Certification as Bariatric Surgery Center and Volume Influence the Outcome in RYGB-Data Analysis of German Bariatric Surgery Registry.

    Science.gov (United States)

    Stroh, Christine; Köckerling, F; Lange, V; Wolff, S; Knoll, C; Bruns, C; Manger, Th

    2017-02-01

    To examine the association between the certification as bariatric surgery center and volume and patient outcome, data collected in the German Bariatric Surgery Registry were evaluated. All data were registered prospectively in cooperation with the Institute of Quality Assurance in Surgery at Otto-von-Guericke University Magdeburg. Data collection began in 2005 for all bariatric procedures in an online database. Participation in the quality assurance study is required for all certified bariatric surgery centers in Germany. Descriptive evaluation and matched pairs analysis were performed. Patients were matched via propensity score taking into account BMI, age, and incidence of comorbidities. During the period from 2005 to 2013, 3083 male and 10,639 female patients were operated on with the RYGB primary approach. In Centers of Competence (77.2 %) and non-accredited hospitals (76.3 %), the proportion of female patients was significantly lower than in Centers of Reference/Excellence (78.7 %; p = 0.002). The mean age in Centers of Reference/Excellence (41.2 years) was significantly lower than in Centers of Competence (43.2 years; p bariatric surgery centers with higher volume. The study supports the concept of certification. There are different factors which can and cannot be preoperatively modified and influence the perioperative outcome.

  17. Scientific collaboration and team science: a social network analysis of the centers for population health and health disparities.

    Science.gov (United States)

    Okamoto, Janet

    2015-03-01

    The past decade has seen dramatic shifts in the way that scientific research is conducted as networks, consortia, and large research centers are funded as transdisciplinary, team-based enterprises to tackle complex scientific questions. Key investigators (N = 167) involved in ten health disparities research centers completed a baseline social network and collaboration readiness survey. Collaborative ties existed primarily between investigators from the same center, with just 7 % of ties occurring across different centers. Grants and work groups were the most common types of ties between investigators, with shared presentations the most common tie across different centers. Transdisciplinary research orientation was associated with network position and reciprocity. Center directors/leaders were significantly more likely to form ties with investigators in other roles, such as statisticians and trainees. Understanding research collaboration networks can help to more effectively design and manage future team-based research, as well as pinpoint potential issues and continuous evaluation of existing efforts.

  18. World Trade Center disaster exposure-related probable posttraumatic stress disorder among responders and civilians: a meta-analysis.

    Science.gov (United States)

    Liu, Bian; Tarigan, Lukman H; Bromet, Evelyn J; Kim, Hyun

    2014-01-01

    The World Trade Center (WTC) disaster on September 11, 2001 was an unprecedented traumatic event with long-lasting health consequences among the affected populations in the New York metropolitan area. This meta-analysis aimed to estimate the risk of probable posttraumatic stress disorder (PTSD) associated with specific types of WTC exposures. Meta-analytical findings from 10 studies of 3,271 to 20,294 participants yielded 37 relevant associations. The pooled summary odds ratio (OR) was 2.05 (95% confidence interval (CI): 1.82, 2.32), with substantial heterogeneity linked to exposure classification, cohort type, data source, PTSD assessment instrument/criteria, and lapse time since 9/11. In general, responders (e.g. police, firefighters, rescue/recovery workers and volunteers) had a lower probable PTSD risk (OR = 1.61; 95% CI: 1.39, 1.87) compared to civilians (e.g. residents, office workers, and passersby; OR = 2.71, 95% CI: 2.35, 3.12). The differences in ORs between responders and civilians were larger for physical compared to psychosocial exposure types. We also found that injury, lost someone, and witnessed horror were the three (out of six) most pernicious exposures. These findings suggest that these three exposures should be a particular focus in psychological evaluation and treatment programs in WTC intervention and future emergency preparedness efforts.

  19. World Trade Center disaster exposure-related probable posttraumatic stress disorder among responders and civilians: a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Bian Liu

    Full Text Available The World Trade Center (WTC disaster on September 11, 2001 was an unprecedented traumatic event with long-lasting health consequences among the affected populations in the New York metropolitan area. This meta-analysis aimed to estimate the risk of probable posttraumatic stress disorder (PTSD associated with specific types of WTC exposures. Meta-analytical findings from 10 studies of 3,271 to 20,294 participants yielded 37 relevant associations. The pooled summary odds ratio (OR was 2.05 (95% confidence interval (CI: 1.82, 2.32, with substantial heterogeneity linked to exposure classification, cohort type, data source, PTSD assessment instrument/criteria, and lapse time since 9/11. In general, responders (e.g. police, firefighters, rescue/recovery workers and volunteers had a lower probable PTSD risk (OR = 1.61; 95% CI: 1.39, 1.87 compared to civilians (e.g. residents, office workers, and passersby; OR = 2.71, 95% CI: 2.35, 3.12. The differences in ORs between responders and civilians were larger for physical compared to psychosocial exposure types. We also found that injury, lost someone, and witnessed horror were the three (out of six most pernicious exposures. These findings suggest that these three exposures should be a particular focus in psychological evaluation and treatment programs in WTC intervention and future emergency preparedness efforts.

  20. A satellite-based analysis of the Val d'Agri (South of Italy Oil Center gas flaring emissions

    Directory of Open Access Journals (Sweden)

    M. Faruolo

    2014-06-01

    Full Text Available In this paper the Robust Satellite Techniques (RST, a multi-temporal scheme of satellite data analysis, was implemented to analyze the flaring activity of the largest Italian gas and oil pre-treatment plant (i.e. the Ente Nazionale Idrocarburi – ENI – Val d'Agri Oil Center – COVA. For this site, located in an anthropized area characterized by a~large environmental complexity, flaring emissions are mainly related to emergency conditions (i.e. waste flaring, being the industrial process regulated by strict regional laws. With reference to the peculiar characteristics of COVA flaring, the main aim of this work was to assess the performances of RST in terms of sensitivity and reliability in providing independent estimations of gas flaring volumes in such conditions. In detail, RST was implemented on thirteen years of Moderate Resolution Imaging Spectroradiometer (MODIS medium and thermal infrared data in order to identify the highly radiant records associated to the COVA flare emergency discharges. Then, exploiting data provided by ENI about gas flaring volumes in the period 2003–2009, a MODIS-based regression model was developed and tested. Achieved results indicate that such a model is able to estimate, with a good level of accuracy (R2 of 0.83, emitted gas flaring volumes at COVA.

  1. Gastrointestinal stromal tumor: analysis of 146 cases of the center of reference of the National Cancer Institute--INCA.

    Science.gov (United States)

    Linhares, Eduardo; Gonçalves, Rinaldo; Valadão, Marcus; Vilhena, Bruno; Herchenhorn, Daniel; Romano, Sergio; Ferreira, Maria Aparecida; Ferreira, Carlos Gil; Ramos, Cintia de Araujo; de Jesus, José Paulo

    2011-01-01

    To evaluate the treatment of GIST in INCA. We conducted a retrospective analysis of all cases of GIST treated at INCA in the period from 1997 to 2009. We analyzed 146 patients with a mean age of 44.5 years and female predominance. The main symptom was abdominal pain. We observed the occurrence of a second primary tumor in 22% of cases and 92% of the immunohistochemistry exams were positive for CD117. The most frequent location was in the stomach and the high-risk group was predominant. Surgery was considered R0 (extensive) in 70% of the cases and the main sites of metastases were liver and peritoneum. Overall survival in two and five years was, respectively, 86% and 59%. There was a significant difference between overall survival (p = 0.29) of the high-risk group versus the other. Our patients presented mainly in the form of high-risk disease, with obvious impact on survival. The use of imatinib improved survival of patients with recurrent and metastatic disease. We should study its use in the setting of adjuvant and neoadjuvant therapy to improve results of the high risk group. The creation of reference centers is a need for the study of rare diseases.

  2. A satellite-based analysis of the Val d'Agri (South of Italy) Oil Center gas flaring emissions

    Science.gov (United States)

    Faruolo, M.; Coviello, I.; Filizzola, C.; Lacava, T.; Pergola, N.; Tramutoli, V.

    2014-06-01

    In this paper the Robust Satellite Techniques (RST), a multi-temporal scheme of satellite data analysis, was implemented to analyze the flaring activity of the largest Italian gas and oil pre-treatment plant (i.e. the Ente Nazionale Idrocarburi - ENI - Val d'Agri Oil Center - COVA). For this site, located in an anthropized area characterized by a~large environmental complexity, flaring emissions are mainly related to emergency conditions (i.e. waste flaring), being the industrial process regulated by strict regional laws. With reference to the peculiar characteristics of COVA flaring, the main aim of this work was to assess the performances of RST in terms of sensitivity and reliability in providing independent estimations of gas flaring volumes in such conditions. In detail, RST was implemented on thirteen years of Moderate Resolution Imaging Spectroradiometer (MODIS) medium and thermal infrared data in order to identify the highly radiant records associated to the COVA flare emergency discharges. Then, exploiting data provided by ENI about gas flaring volumes in the period 2003-2009, a MODIS-based regression model was developed and tested. Achieved results indicate that such a model is able to estimate, with a good level of accuracy (R2 of 0.83), emitted gas flaring volumes at COVA.

  3. A satellite-based analysis of the Val d'Agri Oil Center (southern Italy) gas flaring emissions

    Science.gov (United States)

    Faruolo, M.; Coviello, I.; Filizzola, C.; Lacava, T.; Pergola, N.; Tramutoli, V.

    2014-10-01

    In this paper, the robust satellite techniques (RST), a multi-temporal scheme of satellite data analysis, was implemented to analyze the flaring activity of the Val d'Agri Oil Center (COVA), the largest Italian gas and oil pre-treatment plant, owned by Ente Nazionale Idrocarburi (ENI). For this site, located in an anthropized area characterized by a large environmental complexity, flaring emissions are mainly related to emergency conditions (i.e., waste flaring), as industrial processes are regulated by strict regional laws. While regarding the peculiar characteristics of COVA flaring, the main aim of this work was to assess the performances of RST in terms of sensitivity and reliability in providing independent estimations of gas flaring volumes in such conditions. In detail, RST was implemented for 13 years of Moderate Resolution Imaging Spectroradiometer (MODIS) medium and thermal infrared data in order to identify the highly radiant records associated with the COVA flare emergency discharges. Then, using data provided by ENI about gas flaring volumes in the period 2003-2009, a MODIS-based regression model was developed and tested. The results achieved indicate that the such a model is able to estimate, with a good level of accuracy (R2 of 0.83), emitted gas flaring volumes at COVA.

  4. Fort Collins Science Center- Policy Analysis and Science Assistance Branch : Integrating social, behavioral, economic and biological sciences

    Science.gov (United States)

    2010-01-01

    The Fort Collins Science Center's Policy Analysis and Science Assistance (PASA) Branch is a team of approximately 22 scientists, technicians, and graduate student researchers. PASA provides unique capabilities in the U.S. Geological Survey by leading projects that integrate social, behavioral, economic, and biological analyses in the context of human-natural resource interactions. Resource planners, managers, and policymakers in the U.S. Departments of the Interior (DOI) and Agriculture (USDA), State and local agencies, as well as international agencies use information from PASA studies to make informed natural resource management and policy decisions. PASA scientists' primary functions are to conduct both theoretical and applied social science research, provide technical assistance, and offer training to advance performance in policy relevant research areas. Management and research issues associated with human-resource interactions typically occur in a unique context, involve difficult to access populations, require knowledge of both natural/biological science in addition to social science, and require the skill to integrate multiple science disciplines. In response to these difficult contexts, PASA researchers apply traditional and state-of-the-art social science methods drawing from the fields of sociology, demography, economics, political science, communications, social-psychology, and applied industrial organization psychology. Social science methods work in concert with our rangeland/agricultural management, wildlife, ecology, and biology capabilities. The goal of PASA's research is to enhance natural resource management, agency functions, policies, and decision-making. Our research is organized into four broad areas of study.

  5. Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center

    Directory of Open Access Journals (Sweden)

    Carron M

    2016-02-01

    admissions with rocuronium–neostigmine–sugammadex strategy were observed. The potential economic benefit in avoiding postoperative residual curarization (PORC-related ICU admission in the 2013–2014 period was estimated at an average value of €13,548 (€9,316–€23,845. Conclusion: Sugammadex eliminated PORC and associated morbidities. In our center, sugammadex reduced the costs of NMB management and promoted rapid turnover of patients in operating rooms, with total cost-effectiveness that counteracts the disadvantages of its high cost. Keywords: neuromuscular blockade; neuromuscular blocking agents; rocuronium; sugammadex; postoperative residual curarization; cost-benefit analysis.

  6. Advanced Missile Signature Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Missile Signature Center (AMSC) is a national facility supporting the Missile Defense Agency (MDA) and other DoD programs and customers with analysis,...

  7. Theory, Lore, and More: An Analysis of RAD Research in "The Writing Center Journal," 1980-2009

    Science.gov (United States)

    Driscoll, Dana Lynn; Perdue, Sherry Wynn

    2012-01-01

    In the last 15 years, writing center scholars have increasingly called for more evidence to validate writing centers' practices. Work by Paula Gillespie (2002), Neal Lerner (2009), and Isabelle Thompson et al. (2009) underscore this need. Missing from these discussions, however, is a thorough understanding of the past and current research…

  8. An Analysis of Factors that Inhibit Business Use of User-Centered Design Principles: A Delphi Study

    Science.gov (United States)

    Hilton, Tod M.

    2010-01-01

    The use of user-centered design (UCD) principles has a positive impact on the use of web-based interactive systems in customer-centric organizations. User-centered design methodologies are not widely adopted in organizations due to intraorganizational factors. A qualitative study using a modified Delphi technique was used to identify the factors…

  9. An Investigation, Analysis, and Evaluation of Activities Connected with the Operation of Educational Information Service Centers. Final Report.

    Science.gov (United States)

    Sherman, C. Neil; and Others

    This one-year project produced several publications and an evaluative investigation, all having to do with the rapidly growing community of educational information centers. Over 1500 such centers were surveyed by questionnaire to determine their locations, sizes, activities, and holdings. A directory which lists and describes some four hundred…

  10. Economics of data center optics

    Science.gov (United States)

    Huff, Lisa

    2016-03-01

    Traffic to and from data centers is now reaching Zettabytes/year. Even the smallest of businesses now rely on data centers for revenue generation. And, the largest data centers today are orders of magnitude larger than the supercomputing centers of a few years ago. Until quite recently, for most data center managers, optical data centers were nice to dream about, but not really essential. Today, the all-optical data center - perhaps even an all-single mode fiber (SMF) data center is something that even managers of medium-sized data centers should be considering. Economical transceivers are the key to increased adoption of data center optics. An analysis of current and near future data center optics economics will be discussed in this paper.

  11. Botany in children's literature: A content analysis of plant-centered children's picture books that have a plot and characters

    Science.gov (United States)

    Goins, Sheila Lewis

    This content analysis study examined 36 plant-centered children's science picture books that have a plot and characters published from 1950 to present. Botanical subject matter and learning opportunities offered by these books were analyzed, along with the range and frequency of the National Science Education Standards-consistent and age-appropriate plant science concepts and principles. The science graphics, artistic innovations, and story plot of these books were also examined. Rubrics and research-based recommendations were developed to offer parents, teachers, and librarians assistance in identifying, evaluating, and using such books to help children of ages 4--8 learn about plants and enjoy plant science. This genre of children's literature was identified and selected primarily through extensive research at four major, nationally recognized children's literature collections: The Kerlan Collection, The de Grummond Collection, The Center for Children's Books, and The Central Children's Room at the Donnell Library. This study determined that there was a substantial increase in the number of books written in this genre of children's literature from 1990 to 2000. Botanical subject-matter knowledge and learning opportunities offered by these books include biodiversity of plants; characteristics of plants; life cycles of plants; economic botany, ecology, and ethnobotany. The range and frequency of National Standards-consistent and age-appropriate plant science concepts and principles identified within these books, in part, though not exclusively, included the emergent categories of the process of photosynthesis; basic needs of plants; plant structures; external signals affecting plant growth; environmental stress to plants; biodiversity of plants; plants as animal habitats; and common uses of plants. With regard to plant science graphics, 13 books were identified as presenting some type of science graphic, beyond simple illustrations. The most frequently used

  12. Distribution center

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Distribution center is a logistics link fulfill physical distribution as its main functionGenerally speaking, it's a large and hiahly automated center destined to receive goods from various plants and suppliers,take orders,fill them efficiently,and deliver goods to customers as quickly as possible.

  13. Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center.

    Science.gov (United States)

    Carron, Michele; Baratto, Fabio; Zarantonello, Francesco; Ori, Carlo

    2016-01-01

    The aim of the study is to evaluate the clinical and economic impact of introducing a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen for neuromuscular block (NMB) management. We conducted a retrospective analysis of clinical outcomes and cost-effectiveness in five operating rooms at University Hospital of Padova. A clinical outcome evaluation after sugammadex administration as first-choice reversal drug in selected patients (rocuronium-sugammadex) and as rescue therapy after neostigmine reversal (rocuronium-neostigmine-sugammadex) compared to control was performed. A cost-analysis of NMB management accompanying the introduction of a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen was carried out. To such purpose, two periods were compared: 2011-2012, without sugammadex available; 2013-2014, with sugammadex available. A subsequent analysis was performed to evaluate if sugammadex replacing neostigmine as first choice reversal drug is cost-effective. The introduction of a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen reduced the average cost of NMB management by 36%, from €20.8/case to €13.3/case. Patients receiving sugammadex as a first-choice reversal drug (3%) exhibited significantly better train-of-four ratios at extubation (Psugammadex as first-choice reversal drug has been estimated to be €2.9/case. Patients receiving sugammadex as rescue therapy after neostigmine reversal (3.2%) showed no difference in time to discharge to the surgical ward (P=0.44) compared to controls. No unplanned intensive care unit (ICU) admissions with rocuronium-neostigmine-sugammadex strategy were observed. The potential economic benefit in avoiding postoperative residual curarization (PORC)-related ICU admission in the 2013-2014 period was estimated at an average value of €13,548 (€9,316-€23,845). Sugammadex eliminated PORC and associated morbidities. In our center

  14. A propensity score analysis of prehospital factors and directness of transport of major trauma patients to a level I trauma center.

    Science.gov (United States)

    Garwe, Tabitha; Cowan, Linda D; Neas, Barbara R; Sacra, John C; Albrecht, Roxie M; Rich, Katy M

    2011-01-01

    Indications for direct transport may be strongly related to risk of future health outcomes, and these indications may not be adequately controlled by considering only in-hospital variables. This study was designed to identify prehospital factors associated with directness of transport. The study included 2,062 patients treated at a Level I trauma center between January 1, 2006, and December 31, 2007. The outcome of interest was directness of transport to a Level I trauma center. A propensity score analysis was used to identify demographic, clinical, distance, and other injury scene-related variables associated with the probability of direct transport. A total of 1,459 patients were directly transported to the Level I trauma center and 603 were transferred from lower level facilities. Patients were more likely to be transported directly if they had lower Glasgow Comma Scale scores, had penetrating injuries, were involved in traffic-related injuries, were closer to a Level IV or I trauma center, and if an advanced life support emergency medical service agency transported them from the scene. Patients were more likely to initially stop if they required advanced airway management, met at least one anatomic criterion, were further away from a Level I trauma center, or closer to an intermediate facility. Confounding due to unadjusted prehospital factors may be present in studies evaluating the impact of directness of transport on short-term mortality outcomes. Propensity score analysis of treatment indications provides an additional and efficient method to reduce this bias.

  15. Analysis of the confluence of three patterns using the Centering and Pointing System (CAPS) images for the Advanced Radiographic Capability (ARC) at the National Ignition Facility

    Science.gov (United States)

    Leach, Richard R.; Awwal, Abdul; Bliss, Erlan; Roberts, Randy; Rushford, Michael; Wilhelmsen, Karl; Zobrist, Thomas

    2014-09-01

    The Advance Radiographic Capability (ARC) at the National Ignition Facility (NIF) is a laser system that employs up to four petawatt (PW) lasers to produce a sequence of short pulses that generate X-rays which backlight highdensity internal confinement fusion (ICF) targets. Employing up to eight backlighters, ARC can produce an X-ray "motion picture" to diagnose the compression and ignition of a cryogenic deuterium-tritium target with tens-ofpicosecond temporal resolution during the critical phases of an ICF shot. Multi-frame, hard-X-ray radiography of imploding NIF capsules is a capability which is critical to the success of NIF's missions. The function of the Centering and Pointing System (CAPS) in ARC is to provide superimposed near-field and far-field images on a common optical path. The Images are then analyzed to extract beam centering and pointing data for the control system. The images contain the confluence of pointing, centering, and reference patterns. The patterns may have uneven illumination, particularly when the laser is misaligned. In addition, the simultaneous appearance of three reference patterns may be co-incidental, possibly masking one or more of the patterns. Image analysis algorithms have been developed to determine the centering and pointing position of ARC from these images. In the paper we describe the image analysis algorithms used to detect and identify the centers of these patterns. Results are provided, illustrating how well the process meets system requirements.

  16. Theoretical Analysis on the Simultaneous Operation of a Color-Center Laser and a Q-Switched Nd: YAG Laser

    Institute of Scientific and Technical Information of China (English)

    WU Xing; DING Yongkui; ZHANG Rui

    2000-01-01

    The simultaneous operation for the Q- switched Nd: YAG laser at 1.06 and the tunable color-center laser over 1.12~1.26 μm has been realized by using a LiF: F2- color-center crystal both as the Q-switcher for the Nd:YAG laser and as the active medium for the color-center laser. The interaction of the two lasers has been analyzed and calculated with the rate equations. The pulse duration of YAG laser is compressed, in agreement with the experimental results.

  17. A comparison of two experimental design approaches in applying conjoint analysis in patient-centered outcomes research: a randomized trial.

    Science.gov (United States)

    Kinter, Elizabeth T; Prior, Thomas J; Carswell, Christopher I; Bridges, John F P

    2012-01-01

    While the application of conjoint analysis and discrete-choice experiments in health are now widely accepted, a healthy debate exists around competing approaches to experimental design. There remains, however, a paucity of experimental evidence comparing competing design approaches and their impact on the application of these methods in patient-centered outcomes research. Our objectives were to directly compare the choice-model parameters and predictions of an orthogonal and a D-efficient experimental design using a randomized trial (i.e., an experiment on experiments) within an application of conjoint analysis studying patient-centered outcomes among outpatients diagnosed with schizophrenia in Germany. Outpatients diagnosed with schizophrenia were surveyed and randomized to receive choice tasks developed using either an orthogonal or a D-efficient experimental design. The choice tasks elicited judgments from the respondents as to which of two patient profiles (varying across seven outcomes and process attributes) was preferable from their own perspective. The results from the two survey designs were analyzed using the multinomial logit model, and the resulting parameter estimates and their robust standard errors were compared across the two arms of the study (i.e., the orthogonal and D-efficient designs). The predictive performances of the two resulting models were also compared by computing their percentage of survey responses classified correctly, and the potential for variation in scale between the two designs of the experiments was tested statistically and explored graphically. The results of the two models were statistically identical. No difference was found using an overall chi-squared test of equality for the seven parameters (p = 0.69) or via uncorrected pairwise comparisons of the parameter estimates (p-values ranged from 0.30 to 0.98). The D-efficient design resulted in directionally smaller standard errors for six of the seven parameters, of which

  18. Stability and adaptability analysis of rice cultivars using environment-centered yield in two-way ANOVA model

    Directory of Open Access Journals (Sweden)

    D. Sumith De. Z. Abeysiriwardena

    2011-12-01

    Full Text Available Identification of rice varieties with wider adaptability and stability are the important aspects in varietal recommendation to achieve better economic benefits for farmers. Multi locational trails are conducted in different locations / seasons to test and identify the consistently performing varieties in wider environments and location specific high performing varieties. The interaction aspect of varieties with environment is complex and highly variable across locations. Thus, the identifying varieties under these circumstances are difficult for varietal recommendations. However, several methods have been proposed in the recent past with the complex computation requirements. But, the aid of statistical software and other programs capabilities ease the complexity to a large extent. In this study, we employed one of the established techniques called variance component analysis (VCA to make the varietal recommendation for wider adaptability for many varying environments and the location specific recommendations. In this method variety × environment interaction is portioned into components for individual varieties using yield deviation approach. The average effect of variety (environment centered yield deviation - Dk and the stability measure of each variety (variety interaction variance -Sk2 are used make the recommendations. The rice yield data of cultivars of three month maturity duration, cultivated across diverse environments during the 2002/03 wet–season in Sri Lanka was analyzed for making recommendations. Based on the results the variety At581 gave the highest D2ksk value with wide adaptability selected for general recommendation. Varieties Bg305 and At303 also had relatively higher Dk and thus these two can also be selected for general cultivation purpose.

  19. Geriatric assault victims treated at U.S. trauma centers: Five-year analysis of the national trauma data bank.

    Science.gov (United States)

    Rosen, Tony; Clark, Sunday; Bloemen, Elizabeth M; Mulcare, Mary R; Stern, Michael E; Hall, Jeffrey E; Flomenbaum, Neal E; Lachs, Mark S; Eachempati, Soumitra R

    2016-12-01

    While geriatric trauma patients have begun to receive increased attention, little research has investigated assault-related injuries among older adults. Our goal was to describe characteristics, treatment, and outcomes of geriatric assault victims and compare them both to geriatric victims of accidental injury and younger assault victims. We conducted a retrospective analysis of the 2008-2012 National Trauma Data Bank. We identified cases of assault-related injury admitted to trauma centers in patients aged ≥60 using the variable "intent of injury." 3564 victims of assault-related injury in patients aged ≥60 were identified and compared to 200,194 geriatric accident victims and 94,511 assault victims aged 18-59. Geriatric assault victims were more likely than geriatric accidental injury victims to be male (81% vs. 47%) and were younger than accidental injury victims (67±7 vs. 74±9 years). More geriatric assault victims tested positive for alcohol or drugs than geriatric accident victims (30% vs. 9%). Injuries for geriatric assault victims were more commonly on the face (30%) and head (27%) than for either comparison group. Traumatic brain injury (34%) and penetrating injury (32%) occurred commonly. The median injury severity score (ISS) for geriatric assault victims was 9, with 34% having severe trauma (ISS≥16). Median length of stay was 3 days, 39% required ICU care, and in-hospital mortality was 8%. Injury severity was greater in geriatric than younger adult assault victims, and, even when controlling for injury severity, in-hospital mortality, length of hospitalization, and need for ICU-level care were significantly higher in older adults. Geriatric assault victims have characteristics and injury patterns that differ significantly from geriatric accidental injury victims. These victims also have more severe injuries, higher mortality, and poorer outcomes than younger victims. Additional research is necessary to improve identification of these victims and

  20. Passenger Lymphocyte Syndrome (PLS): A Single-center Retrospective Analysis of Minor ABO-incompatible Liver Transplants.

    Science.gov (United States)

    de Bruijn, Sévérine; Philipse, Ester; Couttenye, Marie Madeleine; Bracke, Bart; Ysebaert, Dirk; Michielsen, Peter; Francque, Sven; Vanwolleghem, Thomas; Verlinden, Anke

    2017-03-28

    Background and Aims: Due to the shortage of donor livers, minor ABO-incompatible liver transplantations are commonly performed. Together with the allograft, immunocompetent B-lymphocytes, called passenger lymphocytes, are transplanted. In case of minor ABO-incompatibility, these passenger lymphocytes produce antibodies directed towards the recipient's red blood cells, which causes immune-mediated hemolysis, also known as the passenger lymphocyte syndrome (PLS). Although this is a self-limiting disorder, serious complications can occur, including graft failure. Retrospectively, we evaluated the role of PLS in minor ABO-incompatible liver transplantations performed at our center. Methods: A retrospective analysis was conducted for all minor ABO-incompatible liver transplantations performed at the Antwerp University Hospital between 2003 and 2015. All patient files were inspected for clinical and laboratory findings. In cases of PLS diagnosis, the applied treatment was also studied. Results: In total, 10 patients underwent a minor ABO-incompatible liver transplantation and 4 showed signs of PLS. All 4 PLS patients were treated with different therapeutic strategy, corresponding to the severity of hemolysis. In all 4 cases, PLS resolved following treatment. Conclusion: When performing minor ABO-incompatible liver transplantations, knowledge of PLS is elemental. Next to a high index of clinical suspicion, we suggest routine screening for markers of hemolysis, with emphasis on haptoglobin level and direct antiglobulin test, weekly in the first 4 weeks post-transplantation as well as in case of a sudden hemoglobin drop within the first 3 months after transplantation. Peri- and postoperative transfusion support using donor-compatible blood has been suggested to prevent the occurrence or limit the extent of hemolysis.

  1. Cross-sectional Multi-center Analysis of Portal Hypertension in 163 Children and Young Adults with Biliary Atresia

    Science.gov (United States)

    Shneider, Benjamin L.; Abel, Bob; Haber, Barbara; Karpen, Saul J.; Magee, John C.; Romero, Rene; Schwarz, Kathleen; Bass, Lee M.; Kerkar, Nanda; Miethke, Alexander G.; Rosenthal, Philip; Turmelle, Yumirle; Robuck, Patricia R.; Sokol, Ronald J.

    2012-01-01

    Objectives Biliary atresia (BA) frequently results in portal hypertension (PHT), complications of which lead to significant morbidity and mortality. The Childhood Liver Disease Research and Education Network (ChiLDREN) was utilized to perform a cross-sectional multi-centered analysis of PHT in children with BA. Methods BA subjects receiving medical management at a ChiLDREN site were enrolled. A priori, clinically evident PHT was defined as “definite” when there was either 1) history of a complication of PHT or 2) clinical findings consistent with PHT (both splenomegaly and thrombocytopenia). PHT was denoted as “possible” if one of the findings was present in the absence of a complication, while PHT was “absent” if none of the criteria were met. Results 163 subjects were enrolled between May 2006 and December 2009. At baseline, definite PHT was present in 49%, possible in 17% and absent in 34% of subjects. Demographics, growth and anthropometrics were similar amongst the 3 PHT categories. ALT, GGTP, and sodium levels were similar, while there were significant differences in AST, AST/ALT, albumin, total bilirubin, PT, WBC, platelet count and AST/platelet between definite and absent PHT. Thirty-four percent of those with definite PHT had either PT > 15s or albumin < 3 g/L. Conclusions Clinically definable PHT is present in two thirds of North American long-term BA survivors with their native livers. The presence of PHT is associated with measures of hepatic injury and dysfunction, although in this selected cohort the degree of hepatic dysfunction is relatively mild and growth is preserved. PMID:22903006

  2. Administrative Challenges to the Integration of Oral Health With Primary Care: A SWOT Analysis of Health Care Executives at Federally Qualified Health Centers.

    Science.gov (United States)

    Norwood, Connor W; Maxey, Hannah L; Randolph, Courtney; Gano, Laura; Kochhar, Komal

    Inadequate access to preventive oral health services contributes to oral health disparities and is a major public health concern in the United States. Federally Qualified Health Centers play a critical role in improving access to care for populations affected by oral health disparities but face a number of administrative challenges associated with implementation of oral health integration models. We conducted a SWOT (strengths, weaknesses, opportunities, and threats) analysis with health care executives to identify strengths, weaknesses, opportunities, and threats of successful oral health integration in Federally Qualified Health Centers. Four themes were identified: (1) culture of health care organizations; (2) operations and administration; (3) finance; and (4) workforce.

  3. An Analysis of a VA/DoD High-Tech Joint Venture at Womack Army Medical Center.

    Science.gov (United States)

    1993-07-01

    interest groups to expand the ’ joint venture ’ concept have intensified with the expectation that cost savings will be realized by participating...organizations (Tokarski, 1989). Using a specific example of a local Magnetic Resonance Imager (MRI) joint venture between the Fayetteville Veterans...Administration Medical Center (FVAMC) and Womack Army Medical Center (WAMC), the management problem was to determine how effective this joint venture has been at improving patient access to MRI technology.

  4. Factors associated with family-centered involvement in family practice--a cross-sectional multivariate analysis.

    Science.gov (United States)

    Deutsch, Tobias; Frese, Thomas; Sandholzer, Hagen

    2014-01-01

    The importance of a family-centered approach in family practice has been emphasized. Knowledge about factors associated with higher family-centered involvement seems beneficial to stimulate its realization. German office-based family physicians completed a questionnaire addressing several aspects of family-centered care. Logistic regression was used to identify associations with the involvement overall and in different domains: routine inquiry and documentation of family-related information, family orientation regarding diagnosis and treatment, family-oriented dialogues, family conferences, and case-related collaboration with marriage and family therapists. We found significant associations between physicians' family-centered involvement and expected patient receptiveness, perceived impact of the family's influence on health, self-perceived psychosocial family-care competences (overall and concerning concepts for family orientation, psychosocial intervention in family conferences, and the communication of the idea of family counseling), advanced training in psychosocial primary care (PPC), personal acquaintance with family therapists (regarding case-related collaboration), and rural office environment. Increased emphasis on the family's influence on health in medical education and training, the provision of concepts for a family-centered perspective, and versatile skills for psychosocial intervention and inquiry of patient preferences, as well as the strengthening of networking between family physicians and family therapists, might promote the family-centered approach in family practice.

  5. Analysis on Construction and Operation of Cloud Computing Data Center%云计算数据中心建设运营分析

    Institute of Scientific and Technical Information of China (English)

    曹鲁

    2012-01-01

    通过对现在云计算数据中心的建设成本、市场业务发展和综合管理等方面的详细分析,建立云计算数据中心的建设运营模型,结合现阶段国内外云计算发展情况,给出企业、政府及电信运营商建设运营云计算数据中心的建议和意见。%Detailed analysis of cloud computing data center construction costs, the market for business development and management, constructed cloud computing data center construction and operation models, combined at this stage at home and abroad cloud computing situation, given enterprises, governments and telecommunications suggestions and opinions of the operators in the construction and operation of cloud computing data center.

  6. 现代综合医院介入治疗中心设计浅析%Analysis of the Modern Comprehensive Hospital Interventional Treatment Center Design

    Institute of Scientific and Technical Information of China (English)

    栗树凯

    2014-01-01

    Interventional treatment center is the concept of interventional radiology in spatial properties with DSA gra-dual y produce department in the development many diseases diagnosis and treatment. This article takes the interventional therapy center as the research object, combines with the actual engineering case to analysis and hope to provide reference for interventional treatment center design.%介入治疗中心是介入放射学在空间属性上的概念,是随着 DSA 在多种疾病诊断治疗方面的不断发展而逐步产生的科室,本文以介入治疗中心为研究对象,结合实际工程案例进行分析,希望为介入治疗中心设计提供参考。

  7. Analysis of causes of death among HIV-infected patients of Kiev Regional AIDS Center during 2013

    Directory of Open Access Journals (Sweden)

    Tetiana Stepchenkova

    2014-11-01

    Full Text Available Ukraine is a leader in Europe in the prevalence of HIV infection. There are up to 270 thousand people, who are living with HIV. Since 1987, in Ukraine, 33,149 HIV-infected people died. During the first six months of 2013, of all the dead, who were suffering from HIV and in need of antiretroviral treatment (ART at the time of death, 41% received treatment and only 5.7% received ART for more than one year. Specialists of Kiev Regional AIDS Center analyzed mortality among the patients of the centre, in order to determine the most frequent cause of death, set the group most at risk and to develop effective measures to reduce mortality among HIV-infected patients. In Kiev AIDS Center, 10,000 people are under medical observation and 4004 of them are taking ART. During 2013, 305 persons died: 217 were women and 88 were men which included 3 children under 14 years. Most of the dead – 272 (89% were aged 25–49. Among the total number of the dead, 125 people (41% were receiving ART, 53 of them (17% were receiving ART for at least one year and 39 of them (13% were receiving ART for less than one month. Hundred and fifty-eight people (52% required ART and 22 (7% did not need therapy. Hundred and ninety-two patients (63% were in four clinical stage of HIV infection. Hundred and ten of them had HIV+TB co-infection. Twenty patients died due to TB and 12 patients died due to hepatitis b virus/hepatitis c virus (HBV/HCV. Among these patients, 87 people (39% were taking ART and 136 persons (61% were in need of ART, but did not get it. Nineteen patients were diagnosed with cancer. Sixteen patients, who were co-infected HIV+TB had a CD4 cell count of more than 300. Based on this analysis, we can conclude that the main causes of high mortality among HIV-infected patients in 2013 were late diagnosis of HIV, besides a large number (52% of patients, who were in need of ART did not take it. A large number (40% among those who died were patients co-infected with HIV

  8. Analysis of histopathological pattern of kidney biopsy specimens in Kuwait: A single-center, five-year prospective study

    Directory of Open Access Journals (Sweden)

    Emad Abdallah

    2015-01-01

    Full Text Available Glomerulonephritis (GN varies in incidence in different geographical areas due to different socioeconomic conditions and ethnicity, genetic variability and environmental factors. Our study is aimed to determine the histopathological pattern of kidney biopsies in Kuwait over the preceding five years. In a prospective study, we analyzed the clinical and pathological data of 214 kidney biopsies that were performed during the period from November 2009 to November 2014 at the Al-Khezam Dialysis Center, Al-Adan Hospital, Kuwait. Kidney biopsies were performed percutaneously using an automated gun guided by ultrasound. The biopsy samples were processed for light microscopy and immunofluorescence. Electron microscopy was performed only in selected cases. Age, gender, serum creatinine, 24-h urinary protein, virology, immunology profiles, indication for renal biopsy and histopathological findings were recorded for analysis. Primary GN was reported in 46.7%, secondary GN was reported in 42.9% and tubulointerstitial disease was reported in 10.3% of the 214 kidney biopsies studied. Among primary GN, membranous GN (MGN was the most common lesion (12.1%, followed by immunoglobulin A nephropathy (IgAN, 11.7%, minimal change disease (9.8%, focal and segmental glomerulosclerosis (9.3%, membranoproliferative GN (1.9%, Alport′s syndrome (1.4% and fibrillary GN (0.46%. Among biopsies that showed secondary GN, lupus nephritis was the most common (11.7%, followed by hypertensive glomerulosclerosis (10.3%, crescentic GN (7.1%, diabetic nephropathy (3.3%, thrombotic microangiopathy (2.3%, amyloidosis (2.3%, post-infectious GN (1.4% and myeloma kidney (0.9%. Among biopsies that showed tubulointerstitial disease, acute interstitial nephritis was the most common lesion (6.1%, followed by chronic interstitial nephritis (2.8% and acute tubular necrosis (1.4%. Our study indicates that MGN was the most common primary GN, followed by IgAN, while lupus nephritis was the most

  9. BACTERIAL AND FUNGAL PATHOGENS IN THE TRANSPLANTATION AND DIALYSIS CENTER. ANALYSIS FOR EIGHTEEN YEARS (1998–2015

    Directory of Open Access Journals (Sweden)

    A. V. Vatazin

    2016-01-01

    Full Text Available Aim: to analyze the dynamics of the microflora and its sensitivity to antibiotics in patients of dialysis and transplantation center.Materials and methods. We have examined the bacteriological test results of 1282 patients with chronic kidney disease, stage 5 (renal transplant recipients and dialysis patients in 1998–2015: 1998–2003 («2003» period, 2008–2011 («2011» period and 2012–2015 («2015» period. Biomaterial: urine, blood, wound effluent, sputum.Results. The incidence (share of all samples of gram «–», gram «+» and fungi was 38, 56, 7% for «2003» period; 48, 69, 13% for «2011» period; 61, 54, 18% for «2015» period. The incidence of gram «–» in blood has significantly increased: 22% in «2003», 13% in «2011», and 45% in «2015», respectively. The incidence of Candida fungi is growing in sputum and urine: 15, 33, 41% and 8, 14, 18% (in 2003, 2011, 2015 respectively. The species composition of the fl ora has also significantly changed. In «2003» the shares of Staphylococcus spp. and Enterococcus spp. were 50 and 33%, in «2015» – 34 and 53% respectively. The shares of E. coli, Klebsiella spp., P. aeruginosa and Acinetobacter spp. were in «2003» 32, 21, 15, 11% respectively, and in «2015» – 17, 32, 9, 22%, respectively. The share of a «problem» genus of Candida: C. glabrata and C. krusei has significantly increased. Their combined share increased from 26 to 38% (2003–2015. There was a significant increase in antibiotic resistance, which is mostly pronounced in Enterococcus spp., Klebsiella spp. and Acinetobacter spp. All gram «+» bacteria in «2003» were susceptible to vancomycin and linezolid, but in «2015» 6% of Enterococcus were resistant to vancomycin. Conclusion. Bacterial profile has significantly changed. Regular analysis of the bacterial fl ora is necessary due to the growing antibiotic resistance. 

  10. Administrative risk quantification of subcutaneous and intravenous therapies in Italian centers utilizing the Failure Mode and Effects Analysis approach

    Directory of Open Access Journals (Sweden)

    Ponzetti C

    2016-08-01

    Full Text Available Clemente Ponzetti,1 Monica Canciani,2 Massimo Farina,2 Sara Era,3 Stefan Walzer4,5 1Gruppo Policlinico di Monza, Alessandria, ANMDO National Association of Hospital Physicians, Bologna, 2Studio EmmEffe Srl, Milan, 3Roche Spa, Monza, Italy; 4MArS Market Access & Pricing Strategy GmbH, Weil am Rhein, 5State University Baden-Wuerttemberg, Health Care Management, Loerrach, Germany Background: In oncology, an important parameter of safety is the potential treatment error in hospitals. The analyzed hypothesis is that of subcutaneous therapies would provide a superior safety benefit over intravenous therapies through fixed-dose administrations, when analyzed with trastuzumab and rituximab.Methods: For the calculation of risk levels, the Failure Mode and Effect Analysis approach was applied. Within this approach, the critical treatment path is followed and risk classification for each individual step is estimated. For oncology and hematology administration, 35 different risk steps were assessed. The study was executed in 17 hematology and 16 breast cancer centers in Italy. As intravenous and subcutaneous were the only injection routes in medical available for trastuzumab and rituximab in oncology at the time of the study, these two therapies were chosen.Results: When the risk classes were calculated, eight high-risk areas were identified for the administration of an intravenous therapy in hematology or oncology; 13 areas would be defined as having a median-risk classification and 14 areas as having a low-risk classification (total risk areas: n=35. When the new subcutaneous formulation would be applied, 23 different risk levels could be completely eliminated (65% reduction. Important high-risk classes such as dose calculation, preparation and package labeling, preparation of the access to the vein, pump infusion preparation, and infusion monitoring were included in the eliminations. The overall risk level for the intravenous administration was estimated

  11. The contribution of multidimensional spatial analysis to a waste management policy: implementation of the ELECTRE method for characterizing transfer centers in the region of Oran

    Science.gov (United States)

    Saidi, A.; Trache, M. A.; Khelfi, M. F.

    2016-08-01

    The social and economic activity steadily growing in our cities creates a significant waste production in constantly evolving. The management of this waste is problematic because it is the center of many issues and interests. Indeed, any action or decision to the collection, transportation, treatment and disposal of waste should be considered in the economic, social, political and especially environmental aspect. A global Geomatic solution requires implementing a GIS with powerful multidimensional spatial analysis tools that support really waste management problem. Algeria has adopted a solution of waste landfill for all urban cities. In the Oran region, it exists three Centers Controlled landfill (CET) which the most important is that of Hassi-Bounif. This center currently meeting the needs of the region is unsustainable solution at the long-term because of its rapid saturation and its geographic location, which is still far from city centers (20-30 km) implying a negative impact on the vehicle park collecting such frequent breakdowns, the rapid degradation, slow delivery time and especially the high cost of the maintenance operation. This phenomenon is aggravated by the absence of real and actual initiatives targeting the recycling and recovery of waste, which makes the CET an endpoint for all types of waste. We present in this study, the use of the ELECTRE method (Multicriteria Analysis) integrated into a GIS to characterize the impact of the implementation of transfers centers at Oran region. The results of this study will accentuate the advantages of the activation of waste warehouse closer to the city, and relieving considerably the volume of transfer towards CET. The objective of our presentation is to show the leading role of the new Geomatics tools and the multidimensional spatial analysis in the apprehension of an environmental problem such the waste management and more generally in the urban management.

  12. The challenge of inclusion in mental health: an analysis of a community center and its work with social bonds

    Directory of Open Access Journals (Sweden)

    Sara Ardila-Gómez

    2016-06-01

    Full Text Available Social inclusion is a key component of transformations in mental health care, because it takes into account the benefits of community life for both those with mental illness and the other members of the community. In order to understand the scope of inclusion within mental health, 45 participants of a community center linked to a psychiatric hospital discharge program which explicitly seeks to provide social inclusion were interviewed. The possible changes in social relationships between users and other community members based in their sustained daily interactions in the community center were explored. Results suggest that the building of social bonds, as part of informal support networks, is one of the benefits of attending the community center. Positive changes in ideas regarding people with “mental illness” were also observed, although these ideas seemed to be more connected to the notion of integration than to social inclusion.

  13. [The challenge of inclusion in mental health: an analysis of a community center and its work with social bonds].

    Science.gov (United States)

    Ardila-Gómez, Sara; Hartfiel, María Isabel; Fernández, Marina A; Ares Lavalle, Guadalupe; Borelli, Mariana; Stolkiner, Alicia

    2016-01-01

    Social inclusion is a key component of transformations in mental health care, because it takes into account the benefits of community life for both those with mental illness and the other members of the community. In order to understand the scope of inclusion within mental health, 45 participants of a community center linked to a psychiatric hospital discharge program which explicitly seeks to provide social inclusion were interviewed. The possible changes in social relationships between users and other community members based in their sustained daily interactions in the community center were explored. Results suggest that the building of social bonds, as part of informal support networks, is one of the benefits of attending the community center. Positive changes in ideas regarding people with "mental illness" were also observed, although these ideas seemed to be more connected to the notion of integration than to social inclusion.

  14. Joint Personnel Recovery Agency Joint Center for Operational Analysis and Lessons Learned Quarterly Bulletin, Volume 7, Issue 2, March 2005

    Science.gov (United States)

    2005-03-01

    Routing Network (SIPRNET) through the use of the Radiant Mercury security guard located at the FBCB2 Program Office Operations Center at Fort Monmouth...prisoners that had died and been cremated . Everything was in order, no names or ashes lost. Once in the camp they were stripped of their clothing

  15. An Analysis of Bilingual Education Programs and Directors in Texas Education Service Center Region Two School Districts

    Science.gov (United States)

    Davila, Michelle Arevalo

    2013-01-01

    In this mixed methods research study, the researcher investigated the difference between additive and subtractive bilingual education programs and student achievement. The researcher examined types of bilingual education and special language programs currently utilized in school districts located within the Education Service Center Region Two…

  16. Which Emotional Profiles Exhibit the Best Learning Outcomes? A Person-Centered Analysis of Students' Academic Emotions

    Science.gov (United States)

    Ganotice, Fraide A., Jr.; Datu, Jesus Alfonso D.; King, Ronnel B.

    2016-01-01

    Previous studies on academic emotions have mostly used variable-centered approaches. Although these studies have elucidated the relationships between academic emotions and key academic outcomes, they cannot identify naturally-occurring groups of students defined by distinct academic emotion profiles. In this study, we adopted a person-centered…

  17. Analysis of Gap in Service Quality in Drug Addiction Treatment Centers of Kerman, Iran, Using SERVQUAL Model.

    Science.gov (United States)

    Naqavi, Mohammad Reza; Refaiee, Raheleh; Baneshi, Mohammad Reza; Nakhaee, Nouzar

    2014-01-01

    Treatment of drug addicts is one of the main strategies of drug control in Iran. Client satisfaction strongly influences the success of any treatment program. This study aimed to explore the difference between customer expectations and perceptions in drug addiction treatment centers of Kerman, Iran, using SERVQUAL model. Using a cross-sectional design 260 clients referring to drug addiction treatment centers of Kerman, were enrolled in 2012. From among 84 clinics, 20 centers were selected randomly. Based on the number of clients registered in each center, a random sample proportional to the size was selected and 290 subjects were invited for interviews. A well validated 22-item questionnaire, which measured the 5 dimensions of service quality (reliability, assurance, tangibility, empathy, and responsiveness), was completed by participants. Each item measured 2 aspects of service quality; expectations and perceptions. Mean ± SD (Standard deviation) age of the subjects was 37.7 ± 9.4. Most of them were male (87.7%). Less than half of them had an educational level lower than diploma. The total score of clients` expectations was higher than their perceptions (P service quality in addiction treatment clinics.

  18. The Beethoven Project: Summary and Retrospective Analysis of the First Five Years of the Center for Successful Child Development.

    Science.gov (United States)

    Ounce of Prevention Fund.

    In 1986, the Ounce of Prevention Fund undertook an ambitious project: creating and operating a family support program for young families with infants and toddlers in the Robert Taylor Homes public housing development in Chicago. The program was the outreach function of the Center for Successful Child Development (CSCD). The CSCD, a comprehensive,…

  19. Wound center facility billing: A retrospective analysis of time, wound size, and acuity scoring for determining facility level of service.

    Science.gov (United States)

    Fife, Caroline E; Walker, David; Farrow, Wade; Otto, Gordon

    2007-01-01

    Outpatient wound center facility reimbursement for Medicare beneficiaries can be a challenge to determine and obtain. To compare methods of calculating facility service levels for outpatient wound centers and to demonstrate the advantages of an acuity-based billing system (one that incorporates components of facility work that is non-reimbursable by procedure codes and that represents an activity-based costing approach to medical billing), a retrospective study of 5,098 patient encounters contained in a wound care-specific electronic medical record database was conducted. Approximately 500 patient visits to the outpatient wound center of a Texas regional hospital between April 2003 and November 2004 were categorized by service level in documentation and facility management software. Visits previously billed using a time-based system were compared to the Centers for Medicare and Medicaid Services' proposed three-tiered wound size-based system. The time-based system also was compared to an acuity-based scoring system. The Pearson correlation coefficient between billed level of service by time and estimated level of service by acuity was 0.442 and the majority of follow-up visits were billed as Level 3 and above (on a time level of 1 to 5) , confirming that time is not a surrogate for actual work performed. Wound size also was found to be unrelated to service level (Pearson correlation = 0.017) and 97% of wound areas were based scoring system produced a near-normal distribution of results, producing more mid-range billings than extremes; no other method produced this distribution. Hospital-based outpatient wound centers should develop, review, and refine acuity score-based models on which to determine billed level of service.

  20. 景德镇陶瓷物流中心规划与功能分析%Planning and Function Analysis of Jingdezhen Ceramic Logistics Center

    Institute of Scientific and Technical Information of China (English)

    周育华; 李映曦

    2013-01-01

    Ceramic global sourcing centers in Jingdezhen is committed to make strategy,build a modern logistics center is a key project.Ceramic logistics center planning should pay attention to function analysis,design capability analysis,operation strategy analysis and the application of information technology.In the four integrated framework,improve overall efficiency and the level of logistics.%在景德镇致力打造成全球陶瓷采购中心的战略中,建设一个现代化的物流中心是一项重点工程。陶瓷物流中心规划中要注重功能分析、设计能力分析、作业策略分析和信息技术的应用。功能上既要考虑陶瓷品类的适用性,也要和城市物流中心和区域物流中心融为一体;设计能力和作业策略分析要满足功能的即时和未来需求;信息技术是物流发挥第三利润源泉的内在动力,在四位一体的框架下,提升物流总体效率和水平。

  1. Behind-the-scenes of patient-centered care: content analysis of electronic messaging among primary care clinic providers and staff.

    Science.gov (United States)

    Stiles, Renée A; Deppen, Stephen A; Figaro, M Kathleen; Gregg, William M; Jirjis, Jim N; Rothman, Russell L; Johnston, Philip E; Miller, Randolph A; Dittus, Robert S; Speroff, Theodore

    2007-12-01

    Transitions to patient-centered health care, the increasing complexity of care, and growth in self-management have all increased the frequency and intensity of clinical services provided outside office settings and between visits. Understanding how electronic messaging, which is often used to coordinate care, affects care is crucial. A taxonomy for codifying clinical text messages into standardized categories could facilitate content analysis of work performed or enhanced via electronic messaging. To codify electronic messages exchanged among the primary care providers and the staff managing diabetes patients at an academic medical center. Retrospective analysis of 27,061 electronic messages exchanged among 578 providers and staff caring for a cohort of 639 adult primary care patients with diabetes between April 1, 2003 and October 31, 2003. Providers and staff using locally developed electronic messaging in an academic medical center's adult primary care clinic. Raw data included clinical text message content, message ID, thread ID, and user ID. Derived measures included user job classification, 35 flags codifying message content, and a taxonomy grouping the flags. Messages contained diverse content: communications with patients, families, and other providers (47.2%), diagnoses (25.4%), documentation (33%), logistics and support functions (29.6%), medications (32.9%), and treatments (28.9%). All messages could be classified; 59.5% of messages addressed 2 or more content areas. Systematic content analysis of provider and staff electronic messages yields specific insight regarding clinical and administrative work carried out via electronic messaging.

  2. Efficient Preparation and Nondestructive Analysis of Photon and Spin Entangled States with Double-Sided Cavity and Nitrogen-Vacancy Center Coupled System

    Science.gov (United States)

    Lin, Jin-Zhong

    2017-02-01

    In this paper, we study the preparation and nondestructive analysis of photon and spin entangled states with double-sided cavity and nitrogen-vacancy center coupled system, which is efficient in weak-coupling regime. The setups are based on some simple linear optical elements, delay lines and conventional photon detectors, which are feasible with existing experimental technology. Numerical simulation demonstrates that all protocols' fidelities and successful probabilities are high in principle. Therefore, our protocols may be useful for decreasing the experimental requirements for preparation and nondestructive analysis of entangled states.

  3. An Analysis of Information Technology Adoption by IRBs of Large Academic Medical Centers in the United States.

    Science.gov (United States)

    He, Shan; Botkin, Jeffrey R; Hurdle, John F

    2015-02-01

    The clinical research landscape has changed dramatically in recent years in terms of both volume and complexity. This poses new challenges for Institutional Review Boards' (IRBs) review efficiency and quality, especially at large academic medical centers. This article discusses the technical facets of IRB modernization. We analyzed the information technology used by IRBs in large academic institutions across the United States. We found that large academic medical centers have a high electronic IRB adoption rate; however, the capabilities of electronic IRB systems vary greatly. We discuss potential use-cases of a fully exploited electronic IRB system that promise to streamline the clinical research work flow. The key to that approach utilizes a structured and standardized information model for the IRB application.

  4. Design, Implementation and Analysis of Learner-Centered Guided In-Service Programme for Technical Teacher Education

    OpenAIRE

    Tiia Rüütmann; Hants Kipper

    2014-01-01

    The design of learner-centered guided in-service program for technical teacher education has been launched at Estonian Centre for Engineering Pedagogy at Tallinn University of Technology. The aim of the program has been facilitating the initial in-service teaching experience, involving mentoring, peer support and cognitive apprenticeship. The emphasis has been on teaching for knowledge application, including the choice of content and processes, motivation, reflection, problem-solving, choice ...

  5. An analysis of clinical process measures for acute healthcare delivery in Appalachia: The Roane Medical Center experience

    OpenAIRE

    Sills Eric; Hancock John S; Pope Karla

    2006-01-01

    Abstract Objective To survey management of selected emergency healthcare needs in a Tennessee community hospital. Materials and methods In this descriptive report, discharges and associated standard process measures were retrospectively studied for Roane Medical Center (RMC) in Harriman, Tennessee (pop. 6,757). Hospital data were extracted from a nationwide database of short-term acute care hospitals to measure 16 quality performance measures in myocardial infarction (MI), heart failure, and ...

  6. Barrier Island Dynamics Using Mass Center Analysis: A New Way to Detect and Track Large-Scale Change

    Directory of Open Access Journals (Sweden)

    Paul Paris

    2014-01-01

    Full Text Available A geographic information system (GIS was used to introduce and test a new method for quantitatively characterizing topographic change. Borrowing from classic Newtonian mechanics, the concept of a body’s center of mass is applied to the geomorphic landscape, and the barrier island environment in particular, to evaluate the metric’s potential as a proxy for detecting, tracking and visualizing change. Two barrier islands along North Carolina’s Outer Banks are used to test this idea: Core Banks, uninhabited and largely-undeveloped, and Hatteras Island, altered by the presence of a protective dune system. Findings indicate that for Core Banks, the alongshore change in the center of mass is in accord with dominate littoral transport and wind conditions. Cross-shore change agrees with independent estimates for the island migration rates. This lends credence to our assertion that the mass center metric has the potential to be a viable proxy for describing wholesale barrier migration and would be a valuable addition to the already-established ocean shoreline and subaerial volume metrics. More research is, however, required to demonstrate efficacy.

  7. Centering in Japanese Discourse

    CERN Document Server

    Walker, M; Côté, S; Walker, Marilyn; Iida, Masayo; Cote, Sharon

    1996-01-01

    In this paper we propose a computational treatment of the resolution of zero pronouns in Japanese discourse, using an adaptation of the centering algorithm. We are able to factor language-specific dependencies into one parameter of the centering algorithm. Previous analyses have stipulated that a zero pronoun and its cospecifier must share a grammatical function property such as {\\sc Subject} or {\\sc NonSubject}. We show that this property-sharing stipulation is unneeded. In addition we propose the notion of {\\sc topic ambiguity} within the centering framework, which predicts some ambiguities that occur in Japanese discourse. This analysis has implications for the design of language-independent discourse modules for Natural Language systems. The centering algorithm has been implemented in an HPSG Natural Language system with both English and Japanese grammars.

  8. Stress Analysis and Testing at the Marshall Space Flight Center to Study Cause and Corrective Action of Space Shuttle External Tank Stringer Failures

    Science.gov (United States)

    Wingate, Robert J.

    2012-01-01

    After the launch scrub of Space Shuttle mission STS-133 on November 5, 2010, large cracks were discovered in two of the External Tank intertank stringers. The NASA Marshall Space Flight Center, as managing center for the External Tank Project, coordinated the ensuing failure investigation and repair activities with several organizations, including the manufacturer, Lockheed Martin. To support the investigation, the Marshall Space Flight Center formed an ad-hoc stress analysis team to complement the efforts of Lockheed Martin. The team undertook six major efforts to analyze or test the structural behavior of the stringers. Extensive finite element modeling was performed to characterize the local stresses in the stringers near the region of failure. Data from a full-scale tanking test and from several subcomponent static load tests were used to confirm the analytical conclusions. The analysis and test activities of the team are summarized. The root cause of the stringer failures and the flight readiness rationale for the repairs that were implemented are discussed.

  9. Analysis of Inpatient Bed Allocation Equity and Utilization in the City Community Health Service Center of China

    Institute of Scientific and Technical Information of China (English)

    许静; 吴妮娜; 金生国; 王芳; 王云霞; 刘利群; 卢祖洵

    2010-01-01

    The objective of this study was to examine the inpatient bed(IB) allocation equity and utilization in Chinese city community health service centers(CHSCs).The data were derived from the Baseline Survey of National City Community Health Service System Building Project,which was conducted in 1917 CHSCs in 28 cities in 2007.The IB allocation was analyzed in terms of IB allocation quantity and distribution equity,and the IB utilization was analyzed by the IB utilization rate and average length of stay of the CH...

  10. [Analysis of teaching of the discipline Nursing in Surgical Center in schools of São Paulo].

    Science.gov (United States)

    Leite, Aline Suelem; Turrini, Ruth Natalia Teresa

    2014-01-01

    The study aimed to characterize the teaching of Nursing in Surgical Center in relation to work load, content and specific curriculum component; and to identify the perspectives and experiences of teachers in teaching this content. This is a descriptive study of quantitative and qualitative approach, that used a semi structured instrument for data collection, with questions related to teaching discipline, sent by email to the coordinators of the courses of Bachelor of Nursing from 219 schools in the state of São Paulo, registered in the website of the Brazilian Ministry of Education. Of the 52 respondents, 90.4% were from private schools, mostly located in the interior of the state (71.1%). From the total of courses, 53.8% ministered the content surgical center within another discipline. The median of content hours was of 64h (40-300h). The respondents commented on the extensive content for a small work load, both practical and theoretical, and its importance for the formation of the generalist nurse.

  11. Ongoing Analyses of Rocket Based Combined Cycle Engines by the Applied Fluid Dynamics Analysis Group at Marshall Space Flight Center

    Science.gov (United States)

    Ruf, Joseph H.; Holt, James B.; Canabal, Francisco

    2001-01-01

    This paper presents the status of analyses on three Rocket Based Combined Cycle (RBCC) configurations underway in the Applied Fluid Dynamics Analysis Group (TD64). TD64 is performing computational fluid dynamics (CFD) analysis on a Penn State RBCC test rig, the proposed Draco axisymmetric RBCC engine and the Trailblazer engine. The intent of the analysis on the Penn State test rig is to benchmark the Finite Difference Navier Stokes (FDNS) code for ejector mode fluid dynamics. The Draco analysis was a trade study to determine the ejector mode performance as a function of three engine design variables. The Trailblazer analysis is to evaluate the nozzle performance in scramjet mode. Results to date of each analysis are presented.

  12. Centering research

    DEFF Research Database (Denmark)

    Katan, Lina Hauge; Baarts, Charlotte

    and collected 24 portfolios in which students reflect auto-ethnographically on their educational practices. Analyzing this qualitative material, we explore how researchers and students respectively read and write to develop and advance their thinking in those learning processes that the two groups fundamentally...... share as the common aim of both research and education. Despite some similarities, we find that how the two groups engage in and benefit from reading and writing diverges significantly. Thus we have even more reason to believe that centering practice-based teaching on these aspects of research is a good...

  13. Building and evaluating an informatics tool to facilitate analysis of a biomedical literature search service in an academic medical center library.

    Science.gov (United States)

    Hinton, Elizabeth G; Oelschlegel, Sandra; Vaughn, Cynthia J; Lindsay, J Michael; Hurst, Sachiko M; Earl, Martha

    2013-01-01

    This study utilizes an informatics tool to analyze a robust literature search service in an academic medical center library. Structured interviews with librarians were conducted focusing on the benefits of such a tool, expectations for performance, and visual layout preferences. The resulting application utilizes Microsoft SQL Server and .Net Framework 3.5 technologies, allowing for the use of a web interface. Customer tables and MeSH terms are included. The National Library of Medicine MeSH database and entry terms for each heading are incorporated, resulting in functionality similar to searching the MeSH database through PubMed. Data reports will facilitate analysis of the search service.

  14. The Tripler Army Medical Center's LE3AN program: a six-month retrospective analysis of program effectiveness for African-American and European-American females.

    Science.gov (United States)

    Simpson, Mark; Earles, Jay; Folen, Raymond; Trammel, Rick; James, Larry

    2004-10-01

    This is a retrospective study that examines the effectiveness of the Tripler Army Medical Center (TAMC) LE3AN Program for weight management among African-American and European American women. African-American and European-American active-duty females who enrolled in the TAMC LE3AN Program between July 1998 and December 2001, and completed six months of follow-up were included in the analysis. The results indicate that the program is associated with significant weight loss for participants, and that it is equally effective for African-American and European-American women. Weekly follow-up visits were correlated with greater weight loss.

  15. Analytical capabilities of the new thermal neutron prompt gamma-ray activation analysis instrument at the National Institute of Standards and Technology Center for Neutron Research

    Energy Technology Data Exchange (ETDEWEB)

    Mackey, E.A. [National Institute of Standards and Technology, Analytical Chemistry Division, Gaithersburg, MD (United States); Anderson, D.L. [US Food and Drug Administration, Elemental Research Branch, College Park, MD (United States)

    2004-07-01

    A new thermal neutron prompt gamma-ray activation analysis (PGAA) instrument was designed and built to replace the original PGAA system at the National Institute of Standards and Technology's Center for Neutron Research. The new PGAA instrument was constructed to achieve a reduction of the fast neutron beam component, a reduction of background gamma-radiation (including gamma-ray lines that directly interfere with element analyses, low-energy scattered gamma rays, and Compton scattered gamma rays), improvement in element sensitivities and limits of detection (LODs), and a simplified instrument set-up procedure. (orig.)

  16. Studies on retrospective analysis of leading primary cancers and improvement of cancer treatment method in Korea cancer center hospital

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong In; Lee, Kang Hyun; Choi, Soo Yong; Kim, Ki Wha; Kang, Sung Mok

    2000-12-01

    a. Retrospective studies included cancers of the stomach, breast, bladder, salivary gland, thyroid, esophagus, endometrium and ovary. (1) Study cancers were analyzed about clinical characteristics, prognostic factors influenced on survival time, survival rate, etc. (2) Among 5,305 study patients, 1,405(26.5%) were identified with death, 3,485(65.7%) were alive and 415(7.8%) were not identified. b. Prospective studies included 10 subjects such as bladder cancer, retinoblastoma, malignant patients, gastric cancer, uterine cervix cancer and ovary cancer. We are continuing registering eligible study patients. c. Results for 11 papers were published at the journal. d. We established follow-up system in order to identify the survival for study subjects through National Statistical Office, Government Provincial Office and Cancer Registration System at Korea Cancer Center Hospital. e. At present, we are establishing computerized registration system about case report form for study cancers.

  17. Design, Implementation and Analysis of Learner-Centered Guided In-Service Programme for Technical Teacher Education

    Directory of Open Access Journals (Sweden)

    Tiia Rüütmann

    2014-03-01

    Full Text Available The design of learner-centered guided in-service program for technical teacher education has been launched at Estonian Centre for Engineering Pedagogy at Tallinn University of Technology. The aim of the program has been facilitating the initial in-service teaching experience, involving mentoring, peer support and cognitive apprenticeship. The emphasis has been on teaching for knowledge application, including the choice of content and processes, motivation, reflection, problem-solving, choice of educational technology, effective teaching methods, teaching models and strategies ཿ concepts, tools and procedures of the field of engineering, organized in ways enabling teachers to formulate real world problems, apply and solve them. The program has been implemented since 2012 and covers IGIP curriculum requirements. In the present article the designed program is described and analyzed.

  18. Chronic idiopathic thrombocytopenic purpura in adult Chinese patients: a retrospective single-centered analysis of 1791 cases

    Institute of Scientific and Technical Information of China (English)

    LI Hong-qiang; ZHANG Lei; ZHAO Hui; JI Lin-xiang; YANG Ren-chi

    2005-01-01

    Background Adult chronic idiopathic thrombocytopenic purpura (ITP) is a common hematologic disease characterized by persistent thrombocytopenia. So far, there were only a few reports on adult Chinese patients with chronic ITP. This study aimed at defining the treatment outcome and prognostic factors for chronic ITP based on a large cohort of Chinese patients followed up for over 25 years at a single center.Methods The medical records of 1791 patients aged 14 years or older who were diagnosed as having chronic ITP at our hospital from 1974 to 1999 were retrospectively analyzed.Conclusions Adult Chinese chronic ITP patients can have long-term remission after steroid therapy and splenectomies. Primary steroid refractoriness is a prognostic factor predicting poor subsequent response to a splenectomy.

  19. Transportation Secure Data Center: Real-World Data for Transportation Planning and Land Use Analysis (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2013-01-01

    The National Renewable Energy Laboratory (NREL) and the U.S. Department of Transportation (DOT) have launched the free, web-based Transportation Secure Data Center (TSDC). The TSDC (www.nrel.gov/tsdc) preserves respondent anonymity while making vital transportation data available to a broad group of users through secure, online access. The TSDC database provides free-of-charge web-based access to valuable transportation data that can be used for: Transit planning, Travel demand modeling, Homeland Security evacuation planning, Alternative fuel station planning, and Validating transportation data from other sources. The TSDC's two levels of access make composite data available with simple online registration, and allow researchers to use detailed spatial data after completing a straight forward application process.

  20. Categorical analysis of factors affecting needs and demands for removable dentures among Alexandria Dental Research Center clientele.

    Science.gov (United States)

    Zeid, W M; Mohamed, M H; Mahdy, N H; El-Tabakh, S M

    1999-01-01

    An accurate assessment of dental needs is important to public health planners. With this information, it is possible to assess future treatment needs and demands for services including those for removable dentures. The present work aimed to estimate the magnitude and types of needs, and demands for partial or complete removable dentures, to study some factors that may affect the identified needs and demands for removable dentures, in addition to studying the factors that may affect satisfaction with the dentures. The present study was conducted in "Alexandria Dental Research Center". Data were collected by means of interview questionnaire, followed by dental examination of all patients attending the center for the sake of removable dental restorations for a period of 6 months. A further follow up over a period of three months was undertaken to the 330 cases recorded. About one third of the cases demanded partial and/or complete dentures and were above 60 years old. The first purpose for construction of new dentures was mastication, followed by cosmetics. Only one quarter of cases decided to have delayed immediate dentures. Diabetics and those having chronic diseases showed more demand for complete dentures. The most discriminating variable between the demand for different dentures was the missing in the lower anterior teeth followed by missing in the upper both anterior and posterior and then missing in the upper anterior teeth. Satisfaction score increased with advance of age, among males, among those for complete dentures, and those who had had previous dentures. Stepwise logistic regression revealed that the best predictor for overall satisfaction was the history of having previous dentures. Results of the present study, suggest that early screening and treatment of diabetic patients, gathering detailed information by means of a questionnaire before new dentures fabrication may be an important tool for the dentist in predicting and consequently enhancing patient

  1. User Centered Design

    DEFF Research Database (Denmark)

    Egbert, Maria; Matthews, Ben

    2012-01-01

    The interdisciplinary approach of User Centered Design is presented here with a focus on innovation in the design and use of hearing technologies as well as on the potential of innovation in interaction. This approach is geared towards developing new products, systems, technologies and practices...... based on an understanding of why so few persons with hearing loss use the highly advanced hearing technologies. In integrating Conversation Analysis (“CA”), audiology and User Centered Design, three disciplines which are collaborating together for the first time, we are addressing the following...

  2. Lied Transplant Center

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The Department of Energy has prepared an Environmental Assessment (DOE/EA-1143) evaluating the construction, equipping and operation of the proposed Lied Transplant Center at the University of Nebraska Medical Center in Omaha, Nebraska. Based on the analysis in the EA, the DOE has determined that the proposed action does not constitute a major federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, the preparation of an Environmental Statement in not required.

  3. Human Factors Process Task Analysis: Liquid Oxygen Pump Acceptance Test Procedure at the Advanced Technology Development Center

    Science.gov (United States)

    Diorio, Kimberly A.; Voska, Ned (Technical Monitor)

    2002-01-01

    This viewgraph presentation provides information on Human Factors Process Failure Modes and Effects Analysis (HF PFMEA). HF PFMEA includes the following 10 steps: Describe mission; Define System; Identify human-machine; List human actions; Identify potential errors; Identify factors that effect error; Determine likelihood of error; Determine potential effects of errors; Evaluate risk; Generate solutions (manage error). The presentation also describes how this analysis was applied to a liquid oxygen pump acceptance test.

  4. Task shifting of HIV/AIDS case management to Community Health Service Centers in urban China: a qualitative policy analysis.

    Science.gov (United States)

    Ma, Fuchang; Lv, Fan; Xu, Peng; Zhang, Dapeng; Meng, Sining; Ju, Lahong; Jiang, Huihui; Ma, Liping; Sun, Jiangping; Wu, Zunyou

    2015-07-02

    The growing number of people living with HIV/AIDS (PLWHA) in China points to an increased need for case management services of HIV/AIDS. This study sought to explore the challenges and enablers in shifting the HIV/AIDS case management services from Centers for Disease Control and Prevention (CDCs) to Community Health Service Centers (CHSCs) in urban China. A qualitative method based on the Health Policy Triangle (HPT) framework was employed to gain in-depth insights into four elements of the task shifting strategy. This included a review on published literature and health policy documents, 15 focus group discussions (FGDs) and 30 in-depth interviews (IDIs) with four types of key actors from three cities in China. A total of 78 studies and 17 policy files at the national, municipal and local levels were obtained and reviewed comprehensively. Three semi-structured interview guides were used to explore key actors' views on shifting the HIV/AIDS case management services to CHSCs. It is necessary and feasible for CHSCs to engage in case management services for PLWHA in local communities. The increasing number of PLWHA and shortage of qualified health professionals in CDCs made shifting case management services downwards to CHSCs an urgent agenda. CHSCs' wide distribution, technical capacity, accessibility and current practice enabled them to carry out case management services for PLWHA. However our findings indicated several challenges in this task shifting process. Those challenges included lack of specific policy and stable financial support for CHSCs, inadequate manpower, relatively low capacity for health service delivery, lack of coordination among sectors, PLWHA's fear for discrimination and privacy disclosure in local communities, which may compromise the effectiveness and sustainability of those services. Shifting the HIV/AIDS case management services from CDCs to CHSCs is a new approach to cope with the rising number of PLWHA in China, but it should be

  5. An analysis of Staphylococcus aureus infections at a military medical center using the PLEX-ID combined polymerase chain reaction-mass spectrometry system.

    Science.gov (United States)

    Washington, Michael A; Agee, Willie A; Kajiura, Lauren; Staege, Catherine M; Uyehara, Catherine Ft; Barnhill, Jason C

    2014-04-01

    Staphylococcus aureus (S. aureus) is a major cause of morbidity in the military health care setting. Culture-based methods are the most common means of identifying infections caused by this agent. However, culture-based methods lack sensitivity and specificity. The Abbott PLEX-ID instrument uses a combination of the polymerase chain reaction and mass spectrometry for the identification of bacterial isolates. We investigated whether the Abbott PLEX-ID system could identify S. aureus in clinical material and facilitate the epidemiological analysis of individual isolates. The PLEX-ID system positively identified 100% of isolates previously found to be methicillin resistant S. aureus by culture. In addition, analysis using the PLEX-ID software revealed that the majority of S. aureus isolates at Tripler Army Medical Center derive from clonal complex 8 and nearly 100% of these strains express the R-variant of the Panton-Valentine leukocidin virulence factor. These results demonstrate the utility of the PLEX-ID system in identifying clinical isolates and reveal an unexpected level of homogeneity among clinical S. aureus isolates recovered at Tripler Army Medical Center. These results also demonstrate the utility of the PLEX-ID system in identifying the resistance patterns, predicting the virulence properties, and tracking the migration of bacterial pathogens in the clinical setting. Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.

  6. Static Analysis of Center Drive Shaft in Suction Opening Mechanism%吸开机构中心传动轴静态分析

    Institute of Scientific and Technical Information of China (English)

    宋柏成

    2015-01-01

    由三维建模软件Solid works建立吸开机构中心传动轴的三维模型,运用ANSYS Workbench分析软件对中心传动轴进行线性静态结构分析,得到位移图和应力图,为轴的进一步优化设计提供了理论依据,结果表明,吸开机构中心传动轴强度满足规定要求。%The three-dimensional model of center drive shaft in suction opening mechanism is established from the 3D model-ing software Solid works in this article, and the linear static structural analysis to the center drive shaft is conducted by using the analysis software ANSYS Workbench, thus the displacement map and the stress diagram are then obtained so as to provide theoretical basis for further optimization design of shaft.The results indicate that the strength of the centre drive shaft in suc-tion opening mechanism could meet the requirements.

  7. What Was (Also) at Stake When a Robot Bathtub Was Implemented in a Danish Elder Center: A Constructivist Secondary Qualitative Analysis.

    Science.gov (United States)

    Beedholm, Kirsten; Frederiksen, Kirsten; Lomborg, Kirsten

    2016-08-01

    Assistive technologies are often considered to be passive tools implemented in targeted processes. Our previous study of the implementation of the robot bathtub in a Danish elder center suggested that purposeful rationality was not the only issue at stake. To further explore this, we conducted a constructivist secondary qualitative analysis. Data included interviews, participant observations, working documents, and media coverage. The analysis was carried out in two phases and revealed that the bathing of the older people was constructed as a problem that could be offensive to the users' integrity, damaging to their well-being, and physically strenuous for the staff. The older users and the nursing staff were constructed as problem carriers. We conclude that technological solutions are not merely neutral and beneficial solutions to existing problems, but are rather part of strategic games contributing to the construction of the very problems they seek to solve.

  8. Core Handling and Real-Time Non-Destructive Characterization at the Kochi Core Center: An Example of Core Analysis from the Chelungpu Fault

    Directory of Open Access Journals (Sweden)

    W. Lin

    2007-11-01

    Full Text Available As an example of core analysis carried out inactive fault drilling programs, we report the procedures of core handling on the drilling site and non-destructive characterization in the laboratory. This analysis was employed onthe core samples taken from HoleBof the Taiwan Chelungpu-fault Drilling Project (TCDP, which penetrated through the active fault that slipped during the 1999 Chi-Chi, Taiwan earthquake. We show results of the non-destructive physical property measurements carried out at the Kochi Core Center (KCC, Japan. Distinct anomalies of lower bulk density and higher magnetic susceptibilitywere recognized in all three fault zones encountered in HoleB. To keep the core samples in good condition before they are used for variousanalyses is crucial. In addition, careful planning for core handlingand core analyses is necessary for successfulinvestigations. doi:10.2204/iodp.sd.s01.35.2007

  9. A retrospective analysis of adverse events in the elderly in a tertiary referral center in Mumbai (Bombay, India

    Directory of Open Access Journals (Sweden)

    Rupawala Abbas

    2009-05-01

    Full Text Available Background : Adverse events (AEs account for significant morbidity and mortality in elderly. Inappropriate medication usage has been regarded as an important factor contributing to AEs in them. Beers criteria are a set of standard criteria for guiding drug prescription in elderly. Objective : To estimate the burden of AEs in the elderly in India and use of Beers criteria for assessing appropriateness of drug prescription in them. Materials and Methods : Data on AEs collected by our tertiary referral center for the years 2005 and 2006 was analyzed. The term ′elderly individuals′ was defined as those aged ≥58 years. An AE was defined as any untoward medical occurrence with a medicinal product in a patient or a clinical investigation, whether or not causally related. Results : In 2005, 321 AEs were reported, and in 2006 there were 673. Of them, those in the elderly constituted 60 (18.9% and 44 (11.8% AEs in the 2 years, respectively. About 7 (11.6% of the AEs in elderly in 2005 were due to medications not fulfilling Beers criteria but none in 2006. Two thirds of the AEs in both years were found to be due to antidiabetics, oral anticoagulants and antiplatelets and drugs with a narrow therapeutic index. Warfarin, digoxin and insulin accounted for a quarter of the AEs. Conclusions : Some commonly used medications account for a major proportion of AEs in elderly. Prospective studies of similar nature could further help us assess the burden of AEs in elderly.

  10. A Comparative Land Use-Based Analysis of Noise Pollution Levels in Selected Urban Centers of Nigeria.

    Science.gov (United States)

    Baloye, David O; Palamuleni, Lobina G

    2015-09-29

    Growth in the commercialization, mobility and urbanization of human settlements across the globe has greatly exposed world urban population to potentially harmful noise levels. The situation is more disturbing in developing countries like Nigeria, where there are no sacrosanct noise laws and regulations. This study characterized noise pollution levels in Ibadan and Ile-Ife, two urban areas of Southwestern Nigeria that have experienced significant increases in population and land use activities. Eight hundred noise measurements, taken at 20 different positions in the morning, afternoon, and evening of carefully selected weekdays, in each urban area, were used for this study. Findings put the average noise levels in the urban centers at between 53 dB(A) and 89 dB (A), a far cry from the World Health Organization (WHO) permissible limits in all the land use types, with highest noise pollution levels recorded for transportation, commercial, residential and educational land use types. The result of the one-way ANOVA test carried out on the dependent variable noise and fixed factor land use types reveals a statistically significant mean noise levels across the study area (F(3,34) = 15.13, p = 0.000). The study underscores noise pollution monitoring and the urgent need to control urban noise pollution with appropriate and effective policies.

  11. A framework for improving access and customer service times in health care: application and analysis at the UCLA Medical Center.

    Science.gov (United States)

    Duda, Catherine; Rajaram, Kumar; Barz, Christiane; Rosenthal, J Thomas

    2013-01-01

    There has been an increasing emphasis on health care efficiency and costs and on improving quality in health care settings such as hospitals or clinics. However, there has not been sufficient work on methods of improving access and customer service times in health care settings. The study develops a framework for improving access and customer service time for health care settings. In the framework, the operational concept of the bottleneck is synthesized with queuing theory to improve access and reduce customer service times without reduction in clinical quality. The framework is applied at the Ronald Reagan UCLA Medical Center to determine the drivers for access and customer service times and then provides guidelines on how to improve these drivers. Validation using simulation techniques shows significant potential for reducing customer service times and increasing access at this institution. Finally, the study provides several practice implications that could be used to improve access and customer service times without reduction in clinical quality across a range of health care settings from large hospitals to small community clinics.

  12. Analysis of a Hybrid PV/Thermal Solar-Assisted Heat Pump System for Sports Center Water Heating Application

    Directory of Open Access Journals (Sweden)

    Y. Bai

    2012-01-01

    Full Text Available The application of solar energy provides an alternative way to replace the primary source of energy, especially for large-scale installations. Heat pump technology is also an effective means to reduce the consumption of fossil fuels. This paper presents a practical case study of combined hybrid PV/T solar assisted heat pump (SAHP system for sports center hot water production. The initial design procedure was first presented. The entire system was then modeled with the TRNSYS 16 computation environment and the energy performance was evaluated based on year round simulation results. The results show that the system COP can reach 4.1 under the subtropical climate of Hong Kong, and as compared to the conventional heating system, a high fractional factor of energy saving at 67% can be obtained. The energy performances of the same system under different climatic conditions, that include three other cities in France, were analyzed and compared. Economic implications were also considered in this study.

  13. Multivariate Multiscale Entropy Applied to Center of Pressure Signals Analysis: An Effect of Vibration Stimulation of Shoes

    Directory of Open Access Journals (Sweden)

    Jiann-Shing Shieh

    2012-11-01

    Full Text Available Falls are unpredictable accidents and resulting injuries can be serious to the elderly. A preventative solution can be the use of vibration stimulus of white noise to improve the sense of balance. In this work, a pair of vibration shoes were developed and controlled by a touch-type switch which can generate mechanical vibration noise to stimulate the patient’s feet while wearing the shoes. In order to evaluate the balance stability and treatment effect of vibrating insoles in these shoes, multivariate multiscale entropy (MMSE algorithm is applied to calculate the relative complexity index of reconstructed center of pressure (COP signals in antero-posterior and medio-lateral directions by the multivariate empirical mode decomposition (MEMD. The results show that the balance stability of 61.5% elderly subjects is improved after wearing the developed shoes, which is more than 30.8% using multiscale entropy. In conclusion, MEMD-enhanced MMSE is able to distinguish the smaller differences between before and after the use of vibration shoes in both two directions, which is more powerful than the empirical mode decomposition (EMD-enhanced MSE in each individual direction.

  14. Location Planning Problem of Service Centers for Sustainable Home Healthcare: Evidence from the Empirical Analysis of Shanghai

    Directory of Open Access Journals (Sweden)

    Gang Du

    2015-11-01

    Full Text Available It is of theoretical and practical significance to understand what factors influence the sustainable development of home healthcare services in China. Based on a face-to-face survey, we find that the location planning, which is decisive for the improvement of patient satisfaction, can effectively reduce the risks, as well as the costs of redundant construction and re-construction of service centers for home healthcare and, thus, helps ensure the sustainability of health and the environment. The purposes of this paper are to investigate the existing problem of home healthcare in Shanghai and to find the optimum location planning scheme under several realistic constraints. By considering differentiated services provided by the medical staff at different levels and the degrees of patient satisfaction, a mixed integer programming model is built to minimize the total medical cost. The IBM ILOGCPLEX is used to solve the above model. Finally, a case study of Putuo district in Shanghai is conducted to validate the proposed model and methodology. Results indicate that the model used in this paper can effectively reduce the total medical cost and enhance the medical sustainability, and therefore, the results of the model can be used as a reference for decision makers on the location planning problem of home healthcare services in China.

  15. Improving Data Collection and Analysis Interface for the Data Acquisition Software of the Spin Laboratory at NASA Glenn Research Center

    Science.gov (United States)

    Abdul-Aziz, Ali; Curatolo, Ben S.; Woike, Mark R.

    2011-01-01

    In jet engines, turbines spin at high rotational speeds. The forces generated from these high speeds make the rotating components of the turbines susceptible to developing cracks that can lead to major engine failures. The current inspection technologies only allow periodic examinations to check for cracks and other anomalies due to the requirements involved, which often necessitate entire engine disassembly. Also, many of these technologies cannot detect cracks that are below the surface or closed when the crack is at rest. Therefore, to overcome these limitations, efforts at NASA Glenn Research Center are underway to develop techniques and algorithms to detect cracks in rotating engine components. As a part of these activities, a high-precision spin laboratory is being utilized to expand and conduct highly specialized tests to develop methodologies that can assist in detecting predetermined cracks in a rotating turbine engine rotor. This paper discusses the various features involved in the ongoing testing at the spin laboratory and elaborates on its functionality and on the supporting data system tools needed to enable successfully running optimal tests and collecting accurate results. The data acquisition system and the associated software were updated and customized to adapt to the changes implemented on the test rig system and to accommodate the data produced by various sensor technologies. Discussion and presentation of these updates and the new attributes implemented are herein reported

  16. Reliability Block Diagram (RBD) Analysis of NASA Dryden Flight Research Center (DFRC) Flight Termination System and Power Supply

    Science.gov (United States)

    Morehouse, Dennis V.

    2006-01-01

    In order to perform public risk analyses for vehicles containing Flight Termination Systems (FTS), it is necessary for the analyst to know the reliability of each of the components of the FTS. These systems are typically divided into two segments; a transmitter system and associated equipment, typically in a ground station or on a support aircraft, and a receiver system and associated equipment on the target vehicle. This analysis attempts to analyze the reliability of the NASA DFRC flight termination system ground transmitter segment for use in the larger risk analysis and to compare the results against two established Department of Defense availability standards for such equipment.

  17. A Person-Centered Perspective on Multidimensional Perfectionism in Canadian and Chinese University Students: A Multigroup Latent Profile Analysis

    Science.gov (United States)

    Smith, Martin M.; Saklofske, Donald H.; Yan, Gonggu; Sherry, Simon B.

    2016-01-01

    This study investigated the generalizability of the tripartite model of perfectionism across Canadian and Chinese university students. Using latent profile analysis and indicators of perfectionistic strivings, perfectionistic concerns, and neuroticism in both groups, the authors derived a 3-profile solution: adaptive perfectionists, maladaptive…

  18. A Person-Centered Perspective on Multidimensional Perfectionism in Canadian and Chinese University Students: A Multigroup Latent Profile Analysis

    Science.gov (United States)

    Smith, Martin M.; Saklofske, Donald H.; Yan, Gonggu; Sherry, Simon B.

    2016-01-01

    This study investigated the generalizability of the tripartite model of perfectionism across Canadian and Chinese university students. Using latent profile analysis and indicators of perfectionistic strivings, perfectionistic concerns, and neuroticism in both groups, the authors derived a 3-profile solution: adaptive perfectionists, maladaptive…

  19. Understanding Differences in Black and White Child Poverty Rates. A Report of the Heritage Center for Data Analysis.

    Science.gov (United States)

    Rector, Robert; Johnson, Kirk A.; Fagan, Patrick F.

    This study uses National Longitudinal Survey of Youth (NLSY) data to analyze differences in black and white child poverty. The NLSY documents family income and underlying conditions such as employment, educational attainment, welfare use, and marriage or divorce. This analysis examines: time in poverty, time on welfare, time in a single parent…

  20. Analysis of the effectiveness of a non-governmental organization in supporting clubfoot clinic at a tertiary care center

    Directory of Open Access Journals (Sweden)

    Sharma Pulak

    2015-01-01

    Full Text Available Background: Since December 2011, a non-governmental organization (NGO has been associated with our clubfoot clinic. Debates related to the effectiveness of NGOs in clinical milieu have raged on for a long time. The aim of this study was to analyze the effectiveness of an NGO in supporting the running of a clubfoot clinic in a tertiary care center. Methods: A descriptive, observational study was conducted from October to December 2014. The three main conceptualizations of effectiveness namely goals, resources and reputation were evaluated for this study, and to analyze them, we compared our treatment data with other published reports, and devised a ten-point questionnaire looking into the working of the NGO. This questionnaire was given to all parents (49 of children with clubfoot attending the clinic and also to an independent observer who was present at the time of patients’ interactions with the counselor. The significance of patients’ and observers’ response was tested by Wilcoxon matched-pairs signed-rank test. Results: 138 cases with 228 feet were registered in the clubfoot clinic till the end of our study. The average number of visits by the patients was 6.67 and 69.47% of cases required tenotomy during the course of treatment. Of the 49 patients, 33 (67.35% graded the role of the NGO as excellent, while the rest showed a good response; 28 observers (57.14% responded as excellent. The average score of parents towards role of the NGO was significantly higher than the observer’s score. Conclusions: The NGO associated with our clubfoot clinic successfully supported formal health care professionals.

  1. Parametric Sensitivity Analysis for the Asian Summer Monsoon Precipitation Simulation in the Beijing Climate Center AGCM Version 2.1

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Ben; Zhang, Yaocun; Qian, Yun; Wu, Tongwen; Huang, Anning; Fang, Yongjie

    2015-07-15

    In this study, we apply an efficient sampling approach and conduct a large number of simulations to explore the sensitivity of the simulated Asian summer monsoon (ASM) precipitation, including the climatological state and interannual variability, to eight parameters related to the cloud and precipitation processes in the Beijing Climate Center AGCM version 2.1 (BCC_AGCM2.1). Our results show that BCC_AGCM2.1 has large biases in simulating the ASM precipitation. The precipitation efficiency and evaporation coefficient for deep convection are the most sensitive parameters in simulating the ASM precipitation. With optimal parameter values, the simulated precipitation climatology could be remarkably improved, e.g. increased precipitation over the equator Indian Ocean, suppressed precipitation over the Philippine Sea, and more realistic Meiyu distribution over Eastern China. The ASM precipitation interannual variability is further analyzed, with a focus on the ENSO impacts. It shows the simulations with better ASM precipitation climatology can also produce more realistic precipitation anomalies during El Niño decaying summer. In the low-skill experiments for precipitation climatology, the ENSO-induced precipitation anomalies are most significant over continents (vs. over ocean in observation) in the South Asian monsoon region. More realistic results are derived from the higher-skill experiments with stronger anomalies over the Indian Ocean and weaker anomalies over India and the western Pacific, favoring more evident easterly anomalies forced by the tropical Indian Ocean warming and stronger Indian Ocean-western Pacific tele-connection as observed. Our model results reveal a strong connection between the simulated ASM precipitation climatological state and interannual variability in BCC_AGCM2.1 when key parameters are perturbed.

  2. An analysis of clinical process measures for acute healthcare delivery in Appalachia: The Roane Medical Center experience

    Directory of Open Access Journals (Sweden)

    Sills Eric

    2006-03-01

    Full Text Available Abstract Objective To survey management of selected emergency healthcare needs in a Tennessee community hospital. Materials and methods In this descriptive report, discharges and associated standard process measures were retrospectively studied for Roane Medical Center (RMC in Harriman, Tennessee (pop. 6,757. Hospital data were extracted from a nationwide database of short-term acute care hospitals to measure 16 quality performance measures in myocardial infarction (MI, heart failure, and pneumonia during the 14 month interval ending March 2005. The data also permitted comparisons with state and national reference groups. Results Of RMC patients with myocardial infarction (MI, 94% received aspirin on arrival, a figure higher than both state (85% and national (91% averages. Assessment of left ventricular dysfunction among heart failure patients was also higher at RMC (98% than the state (74% or national (79% average. For RMC pneumonia patients, 79% received antibiotics within 4 h of admission, which compared favorably with State (76% and national (75% average. RMC scored higher on 13 of 16 clinical process measures (p95% CI compared to state and national averages. Discussion Although acute health care needs are often met with limited resources in medically underserved regions, RMC performed above state and national average for most process measures assessed in this review. Our data were derived from one facility and the associated findings may not be applicable in other healthcare settings. Further studies are planned to track other parameters and specific clinical outcomes at RMC, as well as to identify specific institutional policies that facilitate attainment of target quality measures.

  3. Laparoscopic and open postchemotherapy retroperitoneal lymph node dissection in patients with advanced testicular cancer – a single center analysis

    Directory of Open Access Journals (Sweden)

    Busch Jonas

    2012-05-01

    Full Text Available Abstract Background The open approach represents the gold standard for postchemotherapy retroperitoneal lymph node dissection (O-PCLND in patients with residual testicular cancer. We analyzed laparoscopic postchemotherapy retroperitoneal lymph node dissection (L-PCLND and O-PCLND at our institution. Methods Patients underwent either L-PCLND (n = 43 or O-PCLND (n = 24. Categorical and continuous variables were compared using the Fisher exact test and Mann–Whitney U test respectively. Overall survival was evaluated with the log-rank test. Results Primary histology was embryonal cell carcinomas (18 patients, pure seminoma (2 cases and mixed NSGCTs (47 patients. According to the IGCCCG patients were categorized into “good”, “intermediate” and “poor prognosis” disease in 55.2%, 14.9% and 20.8%, respectively. Median operative time for L-PCLND was 212 min and 232 min for O-PCLND (p = 0.256. Median postoperative duration of drainage and hospital stay was shorter after L-PCLND (0.0 vs. 3.5 days; p 500 ml was almost equally distributed (8.6% vs. 14.2%: p = 0.076. No significant differences were observed for injuries of major vessels and postoperative complications (p = 0.758; p = 0.370. Tumor recurrence occurred in 8.6% following L-PCLND and in 14.2% following O-PCLND with a mean disease-free survival of 76.6 and 89.2 months, respectively. Overall survival was 83.3 and 95.0 months for L-PCNLD and O-PCLND, respectively (p = 0.447. Conclusions L-PCLND represents a safe surgical option for well selected patients at an experienced center.

  4. Analysis of Customer Satisfaction in Case of the Day Center for the Elderly, Cluj-Napoca City Hall

    Directory of Open Access Journals (Sweden)

    Diana Gabriela REIANU

    2014-02-01

    Full Text Available This paper focuses on the analysis of customer satisfaction, being a research whose main purpose was to make an evaluation of social services offered to elderly people. The motivation of this study was to provide data for the organization in order to understand and increase the impact of its social products and services on the beneficiaries, to emphasize ways that can improve the organization’s mechanisms, to help the organization make the services suitable for its beneficiaries, and to take decisions regarding funding, customer needs and program improvement. The study focuses on the strengths and weaknesses within the studied organization based on the results obtained through the analysis of customer satisfaction in relation to the behavior and responsibility of the staff, to the quality of the services and to the variety of the activities that take place within the organization. The conclusions point out ways in which the organization can improve its services, emphasizing future directions of this study.

  5. An Evaluation of the Organizational Structure of Air Force Emergency Operations Centers Using Social Network Analysis and Design Structure Matrices

    Science.gov (United States)

    2013-03-01

    and interpretation. A foundation for this analysis was introduced via graph theory by Dorwin Cartwright in 1956, by broadening Heider’s theory of...sociometric structures” and much more ( Cartwright , 1956). Cartwright’s generalization also expanded Heider’s theory from the 16 typical linear “x” and...Mirshekarian, S. (2000). DSM Macro Programming, Version 2.0. Cambridge: Massachusets Institute of Technology. Cartwright , D. (1956). Structural balance: a

  6. A Mathematical Modeling Approach of the Failure Analysis for the Real-Time Mexican Satellite Space Launch Center

    OpenAIRE

    Omar Ariosto Niño Prieto; Luis Enrique Colmenares Guillén

    2015-01-01

    In this paper, a simulation of the Mathematical Model for Real-Time Satellite Launch Platform approach in Mexico is presented. Mexico holds the fourth best place in the world for building a platform to launch space satellites, since its geographic location is optimal for its construction. It is essential to have the Probabilistic Failure Analysis in Space Systems Engineering from its design, in order to minimize risks and avoid any possible catastrophe. The mathematical approach o...

  7. Comparative Cost Analysis of Increasing Registered Nursing Staff on the Labor and Delivery Unit at the National Naval Medical Center.

    Science.gov (United States)

    1991-07-01

    recognized L&D Nurses 9 the central role of the registered nurse. In its most recent Accreditation Manual for Hospitals, JCAHO requires that "a...far beyond that of a L&D Nurses 60 comparably-sized civilian instituCion . Above all else NNMC is a Navy hospital, with responsibilities far beyond...1990). Accreditation Manual for Hospitals, 1990. Chicago: Author. Klarman, H. E. (1974). Application of cost-benefit analysis to the health services and

  8. The use of failure mode and effect analysis in a radiation oncology setting: the Cancer Treatment Centers of America experience.

    Science.gov (United States)

    Denny, Diane S; Allen, Debra K; Worthington, Nicole; Gupta, Digant

    2014-01-01

    Delivering radiation therapy in an oncology setting is a high-risk process where system failures are more likely to occur because of increasing utilization, complexity, and sophistication of the equipment and related processes. Healthcare failure mode and effect analysis (FMEA) is a method used to proactively detect risks to the patient in a particular healthcare process and correct potential errors before adverse events occur. FMEA is a systematic, multidisciplinary team-based approach to error prevention and enhancing patient safety. We describe our experience of using FMEA as a prospective risk-management technique in radiation oncology at a national network of oncology hospitals in the United States, capitalizing not only on the use of a team-based tool but also creating momentum across a network of collaborative facilities seeking to learn from and share best practices with each other. The major steps of our analysis across 4 sites and collectively were: choosing the process and subprocesses to be studied, assembling a multidisciplinary team at each site responsible for conducting the hazard analysis, and developing and implementing actions related to our findings. We identified 5 areas of performance improvement for which risk-reducing actions were successfully implemented across our enterprise.

  9. Citicoline in severe traumatic brain injury: indications for improved outcome : A retrospective matched pair analysis from 14 Austrian trauma centers.

    Science.gov (United States)

    Trimmel, Helmut; Majdan, Marek; Wodak, Andrea; Herzer, Guenther; Csomor, Daniel; Brazinova, Alexandra

    2017-07-27

    Goal-oriented management of traumatic brain injury (TBI) can save the lives and/or improve the long-term outcome of millions of affected patients worldwide. Additionally, enhancing quality of life will save enormous socio-economic costs; however, promising TBI treatment strategies with neuroprotective agents, such as citicoline (CDP-choline), lacked evidence or produced contradictory results in clinical trials. During a prehospital TBI project to optimize early TBI care within 14 Austrian trauma centers, data on 778 TBI patients were prospectively collected. As preceding evaluations suggested a beneficial outcome in TBI patients treated at the Wiener Neustadt Hospital (WNH), we aimed to investigate the potential role of citicoline administration, solely applied in WNH, in those patients. In a retrospective subgroup analysis we compared 67 patients from WNH with citicoline administration and 67 matched patients from other Austrian centers without citicoline use. Patients with Glasgow Coma Scale score 2 were included. Our analysis revealed significantly reduced rates of intensive care unit (ICU) mortality (5% vs. 24%, p < 0.01), in-hospital mortality (9% vs. 24%, p = 0.035) and 6‑month mortality (13% vs. 28%, p = 0.031), as well as of unfavorable outcome (34% vs. 57%, p = 0.015) and observed vs. expected ratio for mortality (0.42 vs. 0.84) in the WNH (citicoline receivers) group. Despite the limitations of a retrospective subgroup analysis our findings suggest a possible correlation between early and consequent citicoline administration and beneficial outcomes. Therefore, we aim to set up an initiative for a prospective, multicenter randomized controlled trial with citicoline in sTBI (severe TBI) patients.

  10. [An analysis of mental disorders of international students visiting the Mental Health Service at Tsukuba University Health Center].

    Science.gov (United States)

    Hori, Takafumi; Tachikawa, Hirokazu; Ishii, Terumi; Shimada, Naoko; Takemori, Tadashi; Lebowitz, Adam; Asadas, Takashi

    2012-01-01

    With the expected increase in the number of international students coming to Japan as part of the Ministry of Education, Culture, Sports, Science & Technology's "300,000 Foreign Student (Global 30) Plan", the demands on university mental health facilities will also increase. However, the rate of mental disorders of recent international students has not been fully evaluated. As part of an initiative to establish effective treatment measures for the mental health of international students, we investigated the present status and recent trends of these students who visited the Mental Health Service (MHS) in the Tsukuba University Health Center. The demographic characteristics, pathway, stress, and diagnosis of international students who visited the MHS from 2005 to 2010 were investigated retrospectively based on medical records. The subjects were 59 international students (15 male, 44 female; mean age: 28.4). The consultation rate of international students was significantly lower than that of Japanese students each year. Although the rate is almost stable in Japanese students (2.1-2.5%), it has increased significantly in international students, from 0.5% in 2005 to 1.4% in 2010. A larger percentage of the subjects were from Asia (66%), compared to the former Soviet Union (10%) and Europe (7%). A greater proportion of the subjects were graduate students (67%). The diagnoses were as follows: depression (34%), adjustment disorder (32%), insomnia (15%), and schizophrenia (9%). The percentage requiring emergency consultation was 24%, including the most severe cases that had to return to their home country. Sixty-nine percent of the subjects stayed in Japan for more than 1 year. Half of the subjects decided to visit the MHS themselves. The results of the present study show that the consultation rate of international students was lower than that of Japanese students in spite of the "culture shock" experienced by international students. This result is in agreement with

  11. An analysis of cognitive growth of undergraduate students in a problem-centered general chemistry laboratory curriculum

    Science.gov (United States)

    Szeto, Alan Ka-Fai

    This study explored how undergraduate students in a new problem-centered General Chemistry Laboratory curriculum achieved cognitive growth. The new curriculum had three instructional segments: the highly-structured, semi-structured, and open-ended segments. The pedagogical approaches adopted were expository, guided-inquiry, and open-inquiry styles, respectively. Sixty-seven first-year undergraduate students who enrolled in the course in Spring semester, 2000, at Columbia University and three Ph.D.-level chemistry experts were included in the study. A qualitative approach was used including data collection through "think-aloud" problem solving; however, quantitative data such as test scores were also used. The findings from this study confirmed that chemistry experts possessed sophisticated and domain-specific conceptual knowledge structures; they mobilized and applied conceptual knowledge in conjunction with use of heuristics, tacit knowledge, and experience in authentic problem solving. They validated the new curriculum design in preparing students for inquiry-type of problem solving. For novices, solving of semi-structured before ill-structured problems had a positive effect on the solvers' chance of success in solving the latter type of problems as their abilities to mobilize and apply conceptual knowledge and use effective strategies appeared to be critical for successful problem solving. Students in the new course curriculum had grown cognitively as evidenced by their performance on the Case Study projects and Final Examination. High academic achievers were found to perform well independently while the medium and relatively low academic achievers should benefit from sustained and intensive instruction. It is proposed that ill-structured problems should be used to assess and identify the best from the better students. Finally, it was found that no significant change in students' attitudes had resulted from their curriculum experience. Gender and cognitive style

  12. DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis

    Directory of Open Access Journals (Sweden)

    Baseler Michael W

    2007-11-01

    Full Text Available Abstract Background Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by many independent groups. Analysts usually need to visit many of these bioinformatics databases in order to integrate comprehensive annotation information for their genes, which becomes one of the bottlenecks, particularly for the analytic task associated with a large gene list. Thus, a highly centralized and ready-to-use gene-annotation knowledgebase is in demand for high throughput gene functional analysis. Description The DAVID Knowledgebase is built around the DAVID Gene Concept, a single-linkage method to agglomerate tens of millions of gene/protein identifiers from a variety of public genomic resources into DAVID gene clusters. The grouping of such identifiers improves the cross-reference capability, particularly across NCBI and UniProt systems, enabling more than 40 publicly available functional annotation sources to be comprehensively integrated and centralized by the DAVID gene clusters. The simple, pair-wise, text format files which make up the DAVID Knowledgebase are freely downloadable for various data analysis uses. In addition, a well organized web interface allows users to query different types of heterogeneous annotations in a high-throughput manner. Conclusion The DAVID Knowledgebase is designed to facilitate high throughput gene functional analysis. For a given gene list, it not only provides the quick accessibility to a wide range of heterogeneous annotation data in a centralized location, but also enriches the level of biological information for an individual gene. Moreover, the entire DAVID Knowledgebase is freely downloadable or searchable at http://david.abcc.ncifcrf.gov/knowledgebase/.

  13. Analysis of the Causes of Cracks in the Bottom Floor of the Underground Garage of the Hefei Government Affairs Center by using 3D Finite-Element Analysis

    Directory of Open Access Journals (Sweden)

    ZHU Lei

    2015-09-01

    Full Text Available A three-dimensional finite-element software program is used in this study to analyze the causes of cracks in an underground garage. Numerous cracks, serious and regular alike, can be found in the underground garage of the Hefei Government Affairs Center. These cracks are mainly located around the central part of the bottom floor within a 44.6– 57.8 m radius. To explore the causes of the cracks, two attempts are made. On one hand, on-site crack detection and underground water monitoring are conducted. On the other hand, the finite-element software program ANSYS is adopted to establish a finite-element model for the floor–foundation and connecting beam–foundation soil systems of the underground garage. Furthermore, the influences of the underground foundation, underground water level, soil expansion, and Poisson ratio on the bottom floor are calculated and analyzed. On the basis of the calculation and monitoring results, the following conclusion can be made: underground water is the main cause of the bottom floor cracks because underground water exerts a pushing force from the bottom and causes the expansibility of expansive soil. The study aims to provide a theoretical basis for the treatment of cracking in the Hefei Government Affairs Center, and offer a reference for the design, construction, and maintenance of similar projects.

  14. Double divisor mean centering of ratio spectra as a developed spectrophotometric method for the analysis of five-component mixture in drug analysis

    Directory of Open Access Journals (Sweden)

    R’afat Mahmoud Nejem

    2017-01-01

    Full Text Available In this paper a simple method was developed for the simultaneous determination of five-component mixtures, without prior separation steps. The method is based on the combination of double divisor-ratio derivative method and mean centering of ratio spectra method. The mathematical explanation of the procedure is illustrated. The linear determination ranges were 0–30, 0–20, 0–20, 0–45 and 0–100 μg ml−1 for paracetamol, methylparaben, propylparaben, chloropheniramine maleate and pseudoephedrine hydrochloride in 0.1 M HCl, respectively. The proposed method was validated by using synthetic five-component mixtures and applied to the simultaneous determination of these drugs in Decamol Flu syrup. No published spectrophotometric method has been reported for simultaneous determination of the five components of this mixture. So the results of the double divisor mean centering of ratio method (DD-MCR were statistically compared with those of a proposed classical least squares method (CLS.

  15. Analysis of risk factors for valve replacements in 5128 cases from a single heart center in China

    Institute of Scientific and Technical Information of China (English)

    GUO Li-xin; MENG Xu; ZHANG Zhao-guang; BAI Tao

    2010-01-01

    Background Numerous studies have developed a "severity score" or "risk index" for short-term mortality associated with coronary artery bypass grafting (CABG). Due to the different distribution of disease types, the number of valve surgeries in the US and Europe is relatively small. Thus, a risk-scoring system for valve surgeries was developed later and used less than that for the CABG surgery. We retrospectively reviewed 5128 cases of heart valve replacement, to quantitatively assess the risk factors for hospital mortality, and establish risk models for the hospital mortality of cardiac valve replacement patients.Methods A total of 1549 cases of aortic valve replacement, 2460 cases of mitral valve replacement, and 1119 cases of combined aortic valve and mitral valve replacement that were recorded from January 2005 to December 2009 in the cardiac surgery database at Beijing Anzhen Hospital were selected for this study. The cases were randomly assigned to a indicators were selected as possible influencing factors for hospital mortality. Single-factor analysis was performed to screen these factors, and then multi-factor analysis was used to determine the risk factors for hospital mortality in the three surgeries and to establish risk models.Results In the multi-factor analysis, age, body surface area, etiology, cardiopulmonary bypass time, preoperative cardiothoracic ratio, cardiac functional classification, and preoperative creatinine were risk factors for aortic valve replacement. Etiology, preoperative history of heart failure, cardiopulmonary bypass time, preoperative cardiothoracic ratio, and preoperative left ventricular end systolic diameter were risk factors for mitral valve replacement. Age, body mass index, cardiopulmonary bypass time, and cardiac function classification were risk factors for combined aortic valve and mitral valve replacement. The risk models showed good predictive ability (Hosmer-Lemeshow test: P=0.981 in the model for aortic valve

  16. 2011 Las Conchas Post Fire Center Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set consists of photo centers of raw aerial images representing multi-spectral (red, green, blue, near-infrared) digital aerial imagery of the Las Conchas...

  17. New Mexico Museums and Cultural Centers

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset provides an initial version of the locations of museums and cultural centers in New Mexico, in point form, with limited attributes, compiled using...

  18. Analytical and clinical performance of the epoc blood analysis system: experience at a large tertiary academic medical center.

    Science.gov (United States)

    Stotler, Brie A; Kratz, Alexander

    2013-11-01

    To describe validation and performance of epoc, a blood gas analysis point-of-care system, in a live clinical setting. Data were collected for 156 epoc systems over 12 months. Preimplementation precision and correlation studies and postimplementation quality assurance data were collected, including test card, reader, and personal data assistant (PDA) failure rates. The coefficient of variation was clinically acceptable for all analytes. Correlation studies yielded an R(2) from 0.901 (for sodium) to 0.994 (for potassium) with the Nova analyzer and from 0.961 (sodium) to 0.991 (glucose) with the i-STAT. Average test card failure rate was 13%. Of the PDA/reader units, 55% needed repair within 1 year. The analytical performance showed high precision and good correlation with the Nova and i-STAT platforms. Test card and instrument failure rates were higher than that of the i-STAT system.

  19. Analysis of Performance Differences among Students in Urban and Non-urban Centers Based on Compulsory Secondary Education Special Awards

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    Rocío Chao-Fernández

    2015-09-01

    Full Text Available This research analyzes how the teaching-learning contexts (urban and non-urban of four provinces and their different towns influence the school performance of Galician students who apply for the compulsory secondary education (ESO, in Spanish special award. The sample is of 1,212 students who have finished the 4th level of ESO with an average score greater than or equal to 9 between 2008 and 2012. For such purpose, we made a comparative analysis using independent samples with Levene’s test through the SPSS V. 22.0.0.0 statistical package. The results indicate that, out of the 12 scores (Galician, Spanish, foreign language, Mathematics and Social Sciences, Geography and History and a test to choose from different options (Physics and Chemistry, Biology and Geology, Latin, Music, Technology and Arts, students from urban schools get better results in 10 of them (83.33%, with significant differences in 6 subjects.

  20. Is thrombocytosis a useful prognostic marker in renal cell carcinoma? Results of a single-center retrospective analysis

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    Vivek Venkatramani

    2015-01-01

    Full Text Available Introduction: Our aim was to determine the correlation of platelet count with stage and grade of renal cell carcinoma (RCC and to determine whether progression of disease was more likely in those with thrombocytosis. Materials and Methods: A retrospective review of patients with RCC from January 2004 to December 2011 was undertaken. Patients with no preoperative platelet count and those with multiple tumors were excluded. Disease progression was defined as appearance of local recurrence or distant metastasis on follow-up. Thrombocytosis was defined as a platelet count of >400,000/cumm. Standard tests of significance and multivariate analysis using logistic regression were performed. Results: A total of 322 cases were identified. The median follow-up was 7 months (range, 2-84 months. The platelet count correlated significantly with higher Fuhrmann grade, as well as increasing TNM stage at diagnosis. Patients with a platelet count of >400,000/cumm (n = 35 had a significantly higher mean tumor size and worse grade at diagnosis than those with a normal platelet count (n = 287. Patients with thrombocytosis also had a significantly worse stage at presentation. Progression of disease was seen more often in patients with thrombocytosis (28.6% vs 11.9%, P = 0.07. The median time to progression was significantly faster in patients with thrombocytosis (9 vs 18 months, P = 0.018. However, on multivariate analysis TNM stage was the only significant predictor of time to progression. Conclusion: Rising platelet count correlated significantly with advancing stage and grade of disease. Patients with thrombocytosis were significantly more likely to have advanced tumors at presentation, poorer histological features, and rapid disease progression.

  1. Mississippi Technology Transfer Center

    Science.gov (United States)

    1987-01-01

    The Mississippi Technology Transfer Center at the John C. Stennis Space Center in Hancock County, Miss., was officially dedicated in 1987. The center is home to several state agencies as well as the Center For Higher Learning.

  2. Theoretical analysis of geometry and NMR isotope shift in hydrogen-bonding center of photoactive yellow protein by combination of multicomponent quantum mechanics and ONIOM scheme

    Energy Technology Data Exchange (ETDEWEB)

    Kanematsu, Yusuke; Tachikawa, Masanori [Quantum Chemistry Division, Yokohama City University, Seto 22-2, Kanazawa-ku, Yokohama 236-0027 (Japan)

    2014-11-14

    Multicomponent quantum mechanical (MC-QM) calculation has been extended with ONIOM (our own N-layered integrated molecular orbital + molecular mechanics) scheme [ONIOM(MC-QM:MM)] to take account of both the nuclear quantum effect and the surrounding environment effect. The authors have demonstrated the first implementation and application of ONIOM(MC-QM:MM) method for the analysis of the geometry and the isotope shift in hydrogen-bonding center of photoactive yellow protein. ONIOM(MC-QM:MM) calculation for a model with deprotonated Arg52 reproduced the elongation of O–H bond of Glu46 observed by neutron diffraction crystallography. Among the unique isotope shifts in different conditions, the model with protonated Arg52 with solvent effect reasonably provided the best agreement with the corresponding experimental values from liquid NMR measurement. Our results implied the availability of ONIOM(MC-QM:MM) to distinguish the local environment around hydrogen bonds in a biomolecule.

  3. Gray level co-occurrence matrix texture analysis of germinal center light zone lymphocyte nuclei: physiology viewpoint with focus on apoptosis.

    Science.gov (United States)

    Pantic, Igor; Pantic, Senka; Basta-Jovanovic, Gordana

    2012-06-01

    In our study we investigated the relationship between conventional morphometric indicators of nuclear size and shape (area and circularity) and the parameters of gray level co-occurrence matrix texture analysis (entropy, homogeneity, and angular second moment) in cells committed to apoptosis. A total of 432 lymphocyte nuclei images from the spleen germinal center light zones (cells in early stages of apoptosis) were obtained from eight healthy male guinea pigs previously immunized with sheep red blood cells (antigen). For each nucleus, area, circularity, entropy, homogeneity, and angular second moment were determined. All measured parameters of gray level co-occurrence matrix (GLCM) were significantly correlated with morphometric indicators of nuclear size and shape. The strongest correlation was observed between GLCM homogeneity and nuclear area (p GLCM method may be a powerful tool in evaluation of ultrastructural nuclear changes during early stages of the apoptotic process.

  4. Centers for permanent healthcare education: an analysis on the experience of social players in the north of the state of Paraná¹

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    Sônia Cristina Stefano Nicoletto

    2010-01-01

    Full Text Available The policy of continuing healthcare education (CHE aims to develop healthcare workers. With the objective of analyzing the process of implementing and developing the policy in Paraná, a qualitative study involving the six regions of this state is being concluded. This paper relates to the results from the northern region, focusing on the "experiencing CHE" category. In December 2006, two focus groups were conducted involving representatives from management, training, attendance and participation. The data underwent thematic content analysis. The first CHE encounters aroused feelings of mistrust and resistance, and the center was understood as a means of enabling courses and funding sources. There was a diversity of interests and little negotiating capacity. During the process, the study participants began to talk, reflect and participate. Their teamwork was a positive experience. This experience allowed them to recognize the power of CHE for linking and mobilizing different players.

  5. Theoretical analysis of geometry and NMR isotope shift in hydrogen-bonding center of photoactive yellow protein by combination of multicomponent quantum mechanics and ONIOM scheme.

    Science.gov (United States)

    Kanematsu, Yusuke; Tachikawa, Masanori

    2014-11-14

    Multicomponent quantum mechanical (MC_QM) calculation has been extended with ONIOM (our own N-layered integrated molecular orbital + molecular mechanics) scheme [ONIOM(MC_QM:MM)] to take account of both the nuclear quantum effect and the surrounding environment effect. The authors have demonstrated the first implementation and application of ONIOM(MC_QM:MM) method for the analysis of the geometry and the isotope shift in hydrogen-bonding center of photoactive yellow protein. ONIOM(MC_QM:MM) calculation for a model with deprotonated Arg52 reproduced the elongation of O-H bond of Glu46 observed by neutron diffraction crystallography. Among the unique isotope shifts in different conditions, the model with protonated Arg52 with solvent effect reasonably provided the best agreement with the corresponding experimental values from liquid NMR measurement. Our results implied the availability of ONIOM(MC_QM:MM) to distinguish the local environment around hydrogen bonds in a biomolecule.

  6. Epidemiology and mortality of burned patients treated in the University Hospital Center in Tirana, Albania: an analysis of 2337 cases during the period 1998-2008.

    Science.gov (United States)

    Belba, Monika Kristaq; Petrela, Elizana Ylber

    2012-03-01

    The basis for qualitative changes concerning everyday clinical practice are created from epidemiological studies, which not only generalize situations but at the same time provide specific details of the country's features; especially during periods of social transition. The aim of this study was to present demographic and epidemiological features of severe burns treated in the Service of Burns in UHC (University Hospital Center) in Albania and to analyze burn mortality as an important outcome measure. The data used was obtained by the analysis of the medical records of 2337 patients hospitalized in Burns Service ICU near in Tirana, Albania during 1998-2008. Statistical analysis is done with SPSS 15 software. Descriptive analyses, inferential statistics and Chi-square test and Kendall's tau_b are calculated. Logistic regression is used for the prediction of death probability by two risk variables, BSA burned and age. The severe burn incidence was 7 patients per 100,000 persons/year. The overall mean estimated BSA (%) is 22.8±14.7. The main causes of the burn were found to be the scalds in 61.8% of the cases followed by flame (23%), chemicals (10.7%) and electrical injury in 4.5% of the cases. The mean hospital period is 11.6±10. The overall mortality is 10.5%. Based on probability of death, we noticed that older age and larger burn size were associated with a higher likelihood of mortality. The long-term studies and the comparison of our results with the ones of other burn centers has allowed us to determine the actual level of care and as well as to build up contemporary protocols in order to improve the treatment with the objection of decreasing the mortality. Copyright © 2011 Elsevier Ltd and ISBI. All rights reserved.

  7. Timing of Antibiotic Prophylaxis in Elective Caesarean Delivery: A Multi-Center Randomized Controlled Trial and Meta-Analysis.

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    Chuan Zhang

    Full Text Available To compare the effectiveness of antibiotic prophylaxis before skin incision with that after umbilical cord clamping in elective caesarean delivery.We conducted a randomized open-label controlled trial with two parallel arms at three hospitals in western China. Participants meeting the inclusion criteria received antibiotics 30-60 minutes before skin incision while others received antibiotics after umbilical cords clamping. For the meta-analysis, studies were identified from the database of PUBMED, Cochrane Library and EMbase and assessed using the Cochrane risk of bias tool.Four hundred and ten patients were randomized to receive antibiotics before skin incision (n = 205 or after umbilical cords clamping (n = 205. There was no difference in the incidence of postpartum endometritis (RR = 0.34, 95% CI 0.04 to 3.24, wound infection (RR = 3.06, 95% CI 0.13 to 74.69 and total puerperal morbidity (RR = 1.02, 95% CI 0.47 to 2.22. No increase in the incidence of neonatal sepsis (RR = 0.34, 95% CI 0.04 to 3.24, septic workup (RR = 0.41, 95% CI 0.08 to 2.07, or intermediate NICU admission (RR = 0.73, 95% CI 0.24 to 2.26 was observed. The meta-analysis involving nine RCTs showed that no statistically significant difference was found in terms of the risk of postpartum endometritis (RR = 0.73, 95% CI 0.39, 1.36, wound infection (RR = 0.80, 95%CI 0.55, 1.17, or puerperal morbidity (RR = 0.89, 95% CI 0.70, 1.13. No increase in the incidence of neonatal sepsis (RR = 0.65, 95% CI 0.35 to 1.20, septic workup (RR = 0.88, 95% CI 0.50 to 1.54, or intermediate NICU admission (RR = 0.91, 95% CI 0.70 to 1.18 was observed.For elective caesarean delivery, the effects of antibiotic prophylaxis before skin incision and after umbilical cord clamping were equal. Both antibiotic prophylaxis before skin incision and that after umbilical cord clamping were recommended for elective caesarean delivery. The outcome of further studies should address both maternal and neonatal

  8. Molecular analysis of beta-globin gene mutations among Thai beta-thalassemia children: results from a single center study

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    Boonyawat B

    2014-12-01

    Full Text Available Boonchai Boonyawat,1 Chalinee Monsereenusorn,2 Chanchai Traivaree2 1Division of Genetics, Department of Pediatrics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand; 2Division of Hematology/Oncology, Department of Pediatrics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand Background: Beta-thalassemia is one of the most common genetic disorders in Thailand. Clinical phenotype ranges from silent carrier to clinically manifested conditions including severe beta-thalassemia major and mild beta-thalassemia intermedia. Objective: This study aimed to characterize the spectrum of beta-globin gene mutations in pediatric patients who were followed-up in Phramongkutklao Hospital. Patients and methods: Eighty unrelated beta-thalassemia patients were enrolled in this study including 57 with beta-thalassemia/hemoglobin E, eight with homozygous beta-thalassemia, and 15 with heterozygous beta-thalassemia. Mutation analysis was performed by multiplex amplification refractory mutation system (M-ARMS, direct DNA sequencing of beta-globin gene, and gap polymerase chain reaction for 3.4 kb deletion detection, respectively. Results: A total of 13 different beta-thalassemia mutations were identified among 88 alleles. The most common mutation was codon 41/42 (-TCTT (37.5%, followed by codon 17 (A>T (26.1%, IVS-I-5 (G>C (8%, IVS-II-654 (C>T (6.8%, IVS-I-1 (G>T (4.5%, and codon 71/72 (+A (2.3%, and all these six common mutations (85.2% were detected by M-ARMS. Six uncommon mutations (10.2% were identified by DNA sequencing including 4.5% for codon 35 (C>A and 1.1% initiation codon mutation (ATG>AGG, codon 15 (G>A, codon 19 (A>G, codon 27/28 (+C, and codon 123/124/125 (-ACCCCACC, respectively. The 3.4 kb deletion was detected at 4.5%. The most common genotype of beta-thalassemia major patients was codon 41/42 (-TCTT/codon 26 (G>A or betaE accounting for 40%. Conclusion: All of the beta-thalassemia alleles have been characterized by

  9. A longitudinal evaluation of the Center for Epidemiologic Studies-Depression scale (CES-D in a Rheumatoid Arthritis Population using Rasch Analysis

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    Tennant Alan

    2007-07-01

    Full Text Available Abstract Background The aim of this study was to test the internal validity of the total Center for Epidemiologic Studies-Depression (CES-D scale using Rasch analysis in a rheumatoid arthritis (RA population. Methods CES-D was administered to 157 patients with RA over three time points within a 12 month period. Rasch analysis was applied using RUMM2020 software to assess the overall fit of the model, the response scale used, individual item fit, differential item functioning (DIF and person separation. Results Pooled data across three time points was shown to fit the Rasch model with removal of seven items from the original 20-item CES-D scale. It was necessary to rescore the response format from four to three categories in order to improve the scale's fit. Two items demonstrated some DIF for age and gender but were retained within the 13-item CES-D scale. A new cut point for depression score of 9 was found to correspond to the original cut point score of 16 in the full CES-D scale. Conclusion This Rasch analysis of the CES-D in a longstanding RA cohort resulted in the construction of a modified 13-item scale with good internal validity. Further validation of the modified scale is recommended particularly in relation to the new cut point for depression.

  10. Starting a sleep center.

    Science.gov (United States)

    Epstein, Lawrence J; Valentine, Paul S

    2010-05-01

    The demand for sleep medicine services has grown tremendously during the last decade and will likely continue. To date, growth in demand has been met by growth in the number of new sleep centers. The need for more new centers will be dependent on market drivers that include increasing regulatory requirements, personnel shortages, integration of home sleep testing, changes in reimbursement, a shift in emphasis from diagnostics to treatment, and an increased consumer focus on sleep. The decision to open a new center should be based on understanding the market dynamics, completing a market analysis, and developing a business plan. The business plan should include an overview of the facility, a personnel and organizational structure, an evaluation of the business environment, a financial plan, a description of services provided, and a strategy for obtaining, managing, and extending a referral base. Implementation of the business plan and successful operation require ongoing planning and monitoring of operational parameters. The need for new sleep centers will likely continue, but the shifting market dynamics indicate a greater need for understanding the marketplace and careful planning.

  11. A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay

    Directory of Open Access Journals (Sweden)

    Maria Laura Cosetti OLIVEIRA

    2015-01-01

    Full Text Available The aim of this study was to evaluate the demographic, clinical, and therapeutic characteristics and predictive factors of poor prognosis in patients with primary oral squamous cell carcinoma (OSCC in Uruguay. Medical records of patients with the diagnosis of primary OSCC treated between 2000 and 2010 in Uruguayan public hospitals were selected. Data on demographic characteristics, risk factors, clinical features, treatment, and outcome were collected. Associations of independent variables with outcomes were assessed using Pearson chi-squared and Fisher's tests. Of 200 patients with OSCC, 79.4% were men (3.8:1 male:female ratio, with a mean age of 60.75 ± 11.26 years. Tobacco and alcohol consumption were reported by 85.3% and 63.5% of patients, respectively. The most commonly affected location was the tongue (42.5%, with lesions exhibiting ulcerous aspects in 87.9% of cases and pain at the time of diagnosis in 70.4% of cases. One hundred sixty-one (82.1% patients had advanced-stage (III/IV OSCC. Surgery was the most common treatment option, and the overall 5-year survival rate was 58.5%. Univariate analysis showed that the predictors of poor prognosis were clinical aspect, size, regional metastasis, clinical stage, and treatment. In Uruguay, OSCC is diagnosed late, which is associated with a low survival rate. Educational and preventive measures and investment to improve early diagnosis should be undertaken.

  12. Large-Scale Survey of Unselected Automated Visual Fields in a Major Reading Center: Patterns and Data Analysis

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    Lilly Zborowski-Naveh

    2012-01-01

    Full Text Available A prospective, randomized study was conducted to survey a large number of automated perimetry examinations in a central reading institute, obtaining practical information on unselected referred patients and their clinician “consumers”. Visual field records of 1041 patients were obtained, each evaluated by one of three glaucoma specialists. Statistical analysis was applied on demographics, physician characteristics, test reliability and visual field scores. Reliability was scored on a scale of 1 (excellent to 5 (uninterpretable. Data from earlier examinations of these patients was also analyzed. The large majority of patients (70.4% were referred due to glaucoma, ocular hypertension or suspected glaucoma. Most of the patients had threshold strategies: FastPac 24-2 or 30-2 (88.9%, Full Threshold (0.7%, and 10-2 (0.5%. In only 7 patients was short-wavelength automated perimetry (SWAP performed. The Swedish Interactive Testing Algorithm (SITA was applied in 1.0% of cases. More than half (56.8% of the population had a reliability score of 1, and 22.7% had a score of 2, indicating a valid result for 79.4% of patients, providing clinically useful information. Linear regression analyses indicated that the Mean Defect was a better predictor of the visual field score than the Corrected Pattern Standard Deviation (CPSD, for the entire group and for each visual field score subgroup.

  13. Job Satisfaction among Health-Care Staff in Township Health Centers in Rural China: Results from a Latent Class Analysis.

    Science.gov (United States)

    Wang, Haipeng; Tang, Chengxiang; Zhao, Shichao; Meng, Qingyue; Liu, Xiaoyun

    2017-09-22

    Background: The lower job satisfaction of health-care staff will lead to more brain drain, worse work performance, and poorer health-care outcomes. The aim of this study was to identify patterns of job satisfaction among health-care staff in rural China, and to investigate the association between the latent clusters and health-care staff's personal and professional features; Methods: We selected 12 items of five-point Likert scale questions to measure job satisfaction. A latent-class analysis was performed to identify subgroups based on the items of job satisfaction; Results: Four latent classes of job satisfaction were identified: 8.9% had high job satisfaction, belonging to "satisfied class"; 38.2% had low job satisfaction, named as "unsatisfied class"; 30.5% were categorized into "unsatisfied class with the exception of interpersonal relationships"; 22.4% were identified as "pseudo-satisfied class", only satisfied with management-oriented items. Low job satisfaction was associated with specialty, training opportunity, and income inequality. Conclusions: The minority of health-care staff belong to the "satisfied class". Three among four subgroups are not satisfied with income, benefit, training, and career development. Targeting policy interventions should be implemented to improve the items of job satisfaction based on the patterns and health-care staff's features.

  14. A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay.

    Science.gov (United States)

    Oliveira, Maria Laura Cosetti; Wagner, Vivian Petersen; Sant'ana Filho, Manoel; Carrard, Vinicius Coelho; Hugo, Fernando Neves; Martins, Manoela Domingues

    2015-01-01

    The aim of this study was to evaluate the demographic, clinical, and therapeutic characteristics and predictive factors of poor prognosis in patients with primary oral squamous cell carcinoma (OSCC) in Uruguay. Medical records of patients with the diagnosis of primary OSCC treated between 2000 and 2010 in Uruguayan public hospitals were selected. Data on demographic characteristics, risk factors, clinical features, treatment, and outcome were collected. Associations of independent variables with outcomes were assessed using Pearson chi-squared and Fisher's tests. Of 200 patients with OSCC, 79.4% were men (3.8:1 male:female ratio), with a mean age of 60.75 ± 11.26 years. Tobacco and alcohol consumption were reported by 85.3% and 63.5% of patients, respectively. The most commonly affected location was the tongue (42.5%), with lesions exhibiting ulcerous aspects in 87.9% of cases and pain at the time of diagnosis in 70.4% of cases. One hundred sixty-one (82.1%) patients had advanced-stage (III/IV) OSCC. Surgery was the most common treatment option, and the overall 5-year survival rate was 58.5%. Univariate analysis showed that the predictors of poor prognosis were clinical aspect, size, regional metastasis, clinical stage, and treatment. In Uruguay, OSCC is diagnosed late, which is associated with a low survival rate. Educational and preventive measures and investment to improve early diagnosis should be undertaken.

  15. Rural development NGOS and service delivery to the very poor: An empirical analysis of a training center in rural Cameroon

    Directory of Open Access Journals (Sweden)

    Balgah Roland Azibo

    2015-04-01

    Full Text Available The role of development nongovernmental organizations (DNGOs in driving change, servicing the very poor and reducing poverty especially in rural areas in developing countries has been generally affirmed in the rural economics literature. This romantic image accounts to a large extent for the exponential numeric growth observed in the sector, and for burgeoning research on the subject by rural development economists. However, not enough empirical evidence exists on the extent to which such organizations actually service the very poor. This paper uses the example of a rural development NGO in the administrative unit of North West Cameroon to assess the extent to which the very poor actually benefit from DNGO services. A relative poverty approach is applied, allowing for the use of individual indicators and computed poverty indices to compare beneficiaries and non-beneficiaries of the DNGO service delivery based on cross sectional data. The results indicate that the DNGO serviced mainly poor communities. However, a disproportionately higher share of the benefits (60% went to groups that were already well off before service delivery, than to the very poor. The paper then emphasizes the need for DNGOs to carry out poverty analysis prior to service delivery, as a prerequisite to effectively reach out to the very poor, particularly in rural areas in Cameroon.

  16. Analysis of Genetic Diversity and Population Structure of Sesame Accessions from Africa and Asia as Major Centers of Its Cultivation

    Directory of Open Access Journals (Sweden)

    Komivi Dossa

    2016-04-01

    Full Text Available Sesame is an important oil crop widely cultivated in Africa and Asia. Understanding the genetic diversity of accessions from these continents is critical to designing breeding methods and for additional collection of sesame germplasm. To determine the genetic diversity in relation to geographical regions, 96 sesame accessions collected from 22 countries distributed over six geographic regions in Africa and Asia were genotyped using 33 polymorphic SSR markers. Large genetic variability was found within the germplasm collection. The total number of alleles was 137, averaging 4.15 alleles per locus. The accessions from Asia displayed more diversity than those from Africa. Accessions from Southern Asia (SAs, Eastern Asia (EAs, and Western Africa (WAf were highly diversified, while those from Western Asia (WAs, Northern Africa (NAf, and Southeastern Africa (SAf had the lowest diversity. The analysis of molecular variance revealed that more than 44% of the genetic variance was due to diversity among geographic regions. Five subpopulations, including three in Asia and two in Africa, were cross-identified through phylogenetic, PCA, and STRUCTURE analyses. Most accessions clustered in the same population based on their geographical origins. Our results provide technical guidance for efficient management of sesame genetic resources in breeding programs and further collection of sesame germplasm from these different regions.

  17. Analysis of Thrombophilia Test Ordering Practices at an Academic Center: A Proposal for Appropriate Testing to Reduce Harm and Cost.

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    Yu-Min Shen

    Full Text Available Ideally, thrombophilia testing should be tailored to the type of thrombotic event without the influence of anticoagulation therapy or acute phase effects which can give false positive results that may result in long term anticoagulation. However, thrombophilia testing is often performed routinely in unselected patients. We analyzed all consecutive thrombophilia testing orders during the months of October and November 2009 at an academic teaching institution. Information was extracted from electronic medical records for the following: indication, timing, comprehensiveness of tests, anticoagulation therapy at the time of testing, and confirmatory repeat testing, if any. Based on the findings of this analysis, we established local guidelines in May 2013 for appropriate thrombophilia testing, primarily to prevent testing during the acute thrombotic event or while the patient is on anticoagulation. We then evaluated ordering practices 22 months after guideline implementation. One hundred seventy-three patients were included in the study. Only 34% (58/173 had appropriate indications (unprovoked venous or arterial thrombosis or pregnancy losses. 51% (61/119 with an index clinical event were tested within one week of the event. Although 46% (79/173 were found to have abnormal results, only 46% of these had the abnormal tests repeated for confirmation with 54% potentially carrying a wrong diagnosis with long term anticoagulation. Twenty-two months after guideline implementation, there was an 84% reduction in ordered tests. Thus, this study revealed that a significant proportion of thrombophilia testing was inappropriately performed. We implemented local guidelines for thrombophilia testing for clinicians, resulting in a reduction in healthcare costs and improved patient care.

  18. Retrospective comparison of the effectiveness of various treatment modalities of extragastric MALT lymphoma: a single-center analysis.

    Science.gov (United States)

    Wöhrer, Stefan; Kiesewetter, Barbara; Fischbach, Julia; Müllauer, Leonhard; Troch, Marlene; Lukas, Julius; Mayerhoefer, Marius E; Raderer, Markus

    2014-08-01

    We have performed a retrospective analysis of all patients with extragastric mucosa-associated lymphoid tissue (MALT) lymphoma treated at our institution to compare the efficacy of first-line therapeutic modalities including surgery, radiation, systemic therapy, and antibiotics. One hundred eighty-five patients with extragastric MALT lymphoma with a median age of 63 (interquartile range (IQR) 50-74) years and a median follow-up time of 49 (IQR 18-103) months were retrospectively analyzed. Time to progression and time to next therapy were used as surrogate endpoints for efficacy. Patients having either surgery (100 %), chemo/immunotherapy (85.5 %), or radiation (80 %) had significantly (p = 0.01) higher response rates than patients treated with antibiotics (33.3 %). Patients who were irradiated had significantly more progressive disease, but also the longest follow-up time. Stage, elevated LDH, anemia, elevated beta-2 microglobulin, plasmacytic differentiation, monoclonal gammopathy, or autoimmune disease did not influence the rate of disease progression nor did complete remission or partial remission from initial therapy influence time to and rate of progression. There was no significant difference in the median time to progression (p = 0.141), but the estimated time to progression (p = 0.023) as well as the estimated time to next therapy (p = 0.021) was significantly different among the various cohorts favoring surgery, chemo/immunotherapy, and radiation. Our results suggest extragastric MALT lymphoma as a potential systemic disease irrespective of initial stage. Radiation, surgery, and chemo/immunotherapy seem to be equally effective in achieving remissions and prolonged progression free survivals, but a curative potential is questionable. Localized MALT lymphomas affecting the thyroid gland or the lungs have excellent long-term progression-free survivals with surgical treatment only.

  19. Laparoscopic versus open radical cystectomy for elderly patients over 75-year-old: a single center comparative analysis.

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    Shuxiong Zeng

    Full Text Available PURPOSE: To explore the morbidity, mortality and oncological results of laparoscopic radical cystectomy (LRC in the elderly patients over 75-year-old in contrast with open radical cystectomy (ORC. MATERIALS AND METHODS: We analyzed 46 radical cystectomies from January 2009 to December 2013 in patients over 75-year-old in our institute, 21 patients in the LRC group and 25 in the ORC group. Demographic parameters, operative variables and perioperative outcome were retrospectively collected and analyzed between the two groups. Perioperative morbidity and mortality were categorized as early (within 90 days after surgery or late (more than 90 days according to the time of occurrence. RESULTS: Patients in both groups had comparable preoperative characteristics. A significant longer operative time (418 vs. 337 min, p = 0.018 and less estimated blood loss (400 vs. 500 ml p = 0.038 were observed in LRC group compared with ORC group. Infection and ileus were the most common early complications after surgery. Patients underwent ORC suffered from significantly more postoperative ileus (28.0% vs. 4.8%, P = 0.038 and infection (40% vs. 9.5%, P = 0.019 than LRC group within 90 days after surgery. The mortality rate was 4.7% (1/21 and 4% (1/25 for LRC group and ORC group respectively. At a median follow-up of 21 months (range 2-61 months, the Kaplan-Meier survival curves and log-rank analysis demonstrate that there were no significant differences between the LRC and ORC groups in the 3-year overall, cancer-specific, or recurrence-free survival rates. CONCLUSIONS: It is suggested that LRC should be recommended as the primary intervention to treat muscle invasive or high risk non-muscle invasive bladder cancer in elderly patients with a relative long life expectancy.

  20. Analysis of agreement between cardiac risk stratification protocols applied to participants of a center for cardiac rehabilitation

    Science.gov (United States)

    Santos, Ana A. S.; Silva, Anne K. F.; Vanderlei, Franciele M.; Christofaro, Diego G. D.; Gonçalves, Aline F. L.; Vanderlei, Luiz C. M.

    2016-01-01

    ABSTRACT Background Cardiac risk stratification is related to the risk of the occurrence of events induced by exercise. Despite the existence of several protocols to calculate risk stratification, studies indicating that there is similarity between these protocols are still unknown. Objective To evaluate the agreement between the existing protocols on cardiac risk rating in cardiac patients. Method The records of 50 patients from a cardiac rehabilitation program were analyzed, from which the following information was extracted: age, sex, weight, height, clinical diagnosis, medical history, risk factors, associated diseases, and the results from the most recent laboratory and complementary tests performed. This information was used for risk stratification of the patients in the protocols of the American College of Sports Medicine, the Brazilian Society of Cardiology, the American Heart Association, the protocol designed by Frederic J. Pashkow, the American Association of Cardiovascular and Pulmonary Rehabilitation, the Société Française de Cardiologie, and the Sociedad Española de Cardiología. Descriptive statistics were used to characterize the sample and the analysis of agreement between the protocols was calculated using the Kappa coefficient. Differences were considered with a significance level of 5%. Results Of the 21 analyses of agreement, 12 were considered significant between the protocols used for risk classification, with nine classified as moderate and three as low. No agreements were classified as excellent. Different proportions were observed in each risk category, with significant differences between the protocols for all risk categories. Conclusion The agreements between the protocols were considered low and moderate and the risk proportions differed between protocols. PMID:27556385

  1. Coverage of Team Science by Public Information Officers: Content Analysis of Press Releases about the National Science Foundation Science and Technology Centers

    Science.gov (United States)

    Graube, Marita; Clark, Fiona; Illman, Deborah L.

    2010-01-01

    This study examines the content of press releases from the National Science Foundation (NSF) Science and Technology Centers (STCs) to determine how public information officers (PIOs) presented the outcomes of centers to journalists and the public. A total of 68 press releases were analyzed for type of news covered, visibility of centers and their…

  2. Next-Generation Sequencing and Comparative Analysis of Sequential Outbreaks Caused by Multidrug-Resistant Acinetobacter baumannii at a Large Academic Burn Center.

    Science.gov (United States)

    Kanamori, Hajime; Parobek, Christian M; Weber, David J; van Duin, David; Rutala, William A; Cairns, Bruce A; Juliano, Jonathan J

    2015-12-07

    Next-generation sequencing (NGS) analysis has emerged as a promising molecular epidemiological method for investigating health care-associated outbreaks. Here, we used NGS to investigate a 3-year outbreak of multidrug-resistant Acinetobacter baumannii (MDRAB) at a large academic burn center. A reference genome from the index case was generated using de novo assembly of PacBio reads. Forty-six MDRAB isolates were analyzed by pulsed-field gel electrophoresis (PFGE) and sequenced using an Illumina platform. After mapping to the index case reference genome, four samples were excluded due to low coverage, leaving 42 samples for further analysis. Multilocus sequence types (MLST) and the presence of acquired resistance genes were also determined from the sequencing data. A transmission network was inferred from genomic and epidemiological data using a Bayesian framework. Based on single-nucleotide variant (SNV) differences, this MDRAB outbreak represented three sequential outbreaks caused by distinct clones. The first and second outbreaks were caused by sequence type 2 (ST2), while the third outbreak was caused by ST79. For the second outbreak, the MLST and PFGE results were discordant. However, NGS-based SNV typing detected a recombination event and consequently enabled a more accurate phylogenetic analysis. The distribution of resistance genes varied among the three outbreaks. The first- and second-outbreak strains possessed a blaOXA-23-like group, while the third-outbreak strains harbored a blaOXA-40-like group. NGS-based analysis demonstrated the superior resolution of outbreak transmission networks for MDRAB and provided insight into the mechanisms of strain diversification between sequential outbreaks through recombination.

  3. Next-Generation Sequencing and Comparative Analysis of Sequential Outbreaks Caused by Multidrug-Resistant Acinetobacter baumannii at a Large Academic Burn Center

    Science.gov (United States)

    Parobek, Christian M.; Weber, David J.; van Duin, David; Rutala, William A.; Cairns, Bruce A.; Juliano, Jonathan J.

    2015-01-01

    Next-generation sequencing (NGS) analysis has emerged as a promising molecular epidemiological method for investigating health care-associated outbreaks. Here, we used NGS to investigate a 3-year outbreak of multidrug-resistant Acinetobacter baumannii (MDRAB) at a large academic burn center. A reference genome from the index case was generated using de novo assembly of PacBio reads. Forty-six MDRAB isolates were analyzed by pulsed-field gel electrophoresis (PFGE) and sequenced using an Illumina platform. After mapping to the index case reference genome, four samples were excluded due to low coverage, leaving 42 samples for further analysis. Multilocus sequence types (MLST) and the presence of acquired resistance genes were also determined from the sequencing data. A transmission network was inferred from genomic and epidemiological data using a Bayesian framework. Based on single-nucleotide variant (SNV) differences, this MDRAB outbreak represented three sequential outbreaks caused by distinct clones. The first and second outbreaks were caused by sequence type 2 (ST2), while the third outbreak was caused by ST79. For the second outbreak, the MLST and PFGE results were discordant. However, NGS-based SNV typing detected a recombination event and consequently enabled a more accurate phylogenetic analysis. The distribution of resistance genes varied among the three outbreaks. The first- and second-outbreak strains possessed a blaOXA-23-like group, while the third-outbreak strains harbored a blaOXA-40-like group. NGS-based analysis demonstrated the superior resolution of outbreak transmission networks for MDRAB and provided insight into the mechanisms of strain diversification between sequential outbreaks through recombination. PMID:26643351

  4. Modeling, stability analysis, and computational aspects of some simplest nonlinear fuzzy two-term controllers derived via center of area/gravity defuzzification.

    Science.gov (United States)

    Arun, N K; Mohan, B M

    2017-09-01

    The mathematical models reported in the literature so far have been found using Center of Sums (CoS) defuzzification method only. It appears that no one has found models using Center of Area (CoA) or Center of Gravity (CoG) defuzzification method. Although there have been some works reported to deal with modeling of fuzzy controllers via Centroid method, all of them have in fact used CoS method only. In this paper, for the first time mathematical models of the simplest Mamdani type fuzzy Proportional Integral (PI)/Proportional Derivative (PD) controllers via CoG defuzzification are presented. L-type and Γ-type membership functions over different Universes of Discourse (UoDs) are considered for the input variables. L-type, Π-type and Γ-type membership functions are considered for the output variable. Three linear fuzzy control rules relating all four input fuzzy sets to three output fuzzy sets are chosen. Two triangular norms namely Algebraic Product (AP) and Minimum (Min), Maximum (Max) triangular co-norm, and two inference methods, Larsen Product (LP) and Mamdani Minimum (MM), are used. Properties of the models are studied. Stability analysis of closed-loop systems containing one of these controller models in the loop is done using the Small Gain theorem. Since digital controllers are implemented using digital processors, computational and memory requirements of these fuzzy controllers and conventional (nonfuzzy) controllers are compared. A rough estimate of the computational time taken by the digital computer while implementing any of these discrete-time fuzzy controllers is given. Two nonlinear plants are considered to show the superiority of the simplest fuzzy controller obtained using CoA or CoG defuzzification method over the simplest fuzzy controller obtained using CoS method and reported recently. Real-time implementation of one of the developed controller models is done on coupled tank experimental setup to show the feasibility of the developed model

  5. Age-dependent safety analysis of propofol-based deep sedation for ERCP and EUS procedures at an endoscopy training center in a developing country

    Directory of Open Access Journals (Sweden)

    Amornyotin S

    2012-07-01

    Full Text Available Somchai Amornyotin,1,2 Somchai Leelakusolvong,2,3 Wiyada Chalayonnawin,1,2 Siriporn Kongphlay1,21Department of Anesthesiology, 2Siriraj GI Endoscopy Center, 3Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, ThailandIntroduction: Endoscopic retrograde cholangiopancreatography (ERCP and endoscopic ultrasonography (EUS procedures in elderly patients are on the rise, and they play an important role in the diagnosis and management of various gastrointestinal diseases. The use of deep sedation in these patients has been established as a safe and effective technique in Western countries; however, it is uncertain if the situation holds true among Asians. The present study aimed to evaluate the age-dependent safety analysis and clinical efficacy of propofol-based deep sedation (PBDS for ERCP and EUS procedures in adult patients at a World Gastroenterology Organization (WGO Endoscopy Training Center in Thailand.Methods: We undertook a retrospective review of anesthesia or sedation service records of patients who underwent ERCP and EUS procedures. All procedures were performed by staff endoscopists, and all sedations were administered by anesthesia personnel in the endoscopy room.Results: PBDS was provided for 491 ERCP and EUS procedures. Of these, 252 patients (mean age, 45.1 ± 11.1 years, range 17–65 years were in the <65 age group, 209 patients (mean age, 71.7 ± 4.3 years, range 65–80 years were in the 65–80 year-old group, and 30 patients (mean age, 84.6 ± 4.2 years, range 81–97 years were in the >80 age group. Common indications for the procedures were pancreatic tumor, cholelithiasis, and gastric tumor. Fentanyl, propofol, and midazolam were the most common sedative drugs used in all three groups. The mean doses of propofol and midazolam in the very old patients were relatively lower than in the other groups. The combination of propofol, midazolam, and fentanyl, as well as propofol and fentanyl

  6. Analysis of patients with end-stage renal disease on dialysis in Tabuk City, Saudi Arabia: A single-center, three-year retrospective study

    Directory of Open Access Journals (Sweden)

    Fahad M Almutairi

    2017-01-01

    Full Text Available This study was performed to analyze various demographic data such as age, gender, nationality, status of the patients, and the causes of end-stage renal disease (ESRD of 349 patients who were undergoing hemodialysis (HD during the period from January 2013 to December 2015 at the Dialysis Center of King Khalid Hospital in Tabuk City. One hundred and fifty-two patients (43.6% were on HD in 2015. Age of the patients ranged from 9 to 93 years and the mean age was 51.3 ± 17.6 years. Majority of the patients, i.e., 140 (40.1% were in the age group of 40–59 years, followed by the age group of 60–79 years by 27.8% (97 patients. Saudis constituted 84.2% (294 and non-Saudis accounted 15.8% (55 of the patients over the years studied. There were 198 males (56.7% and 151 females (43.3%. The death rate in 2014 was 6.2%, whereas it increased in 2015 to 10.5%. The high escape rate (10.3% of patients was in 2014. Diabetic nephropathy was the most common cause of ESRD, accounting for 30.4% of all cases, followed by unknown etiologies accounting for 25.2%. Nearly 22.6% of all ESRD cases had hypertension. Primary glomerular disease was seen in 8.9% and obstructive uropathy in 3.7%. Other causes constituted 7.4% of the cases. The data of ERSD patients in Tabuk City are comparable with that of other regions of the Kingdom of Saudi Arabia. We conclude that analysis studies of HD centers help to understand the problems and the needs of the patients, find the solutions, and create a connection between the consumers and health-care providers.

  7. Pungency evaluation of onion cultivars from the Venezuelan West-Center region by flow injection analysis-UV-visible spectroscopy pyruvate determination.

    Science.gov (United States)

    Marcos, Pineda; Lué-Merú, Marcó P; Ricardo, Rivas; Máximo, Gallignani; Maribel, Valero; Luis, Burguera José; Marcela, Burguera

    2004-12-15

    A flow injection analysis (FIA) method was developed for the determination of pyruvate in onion cultivars (Allium cepa L.) from the West-Center region of Venezuela. The reference Schwimmer and Weston (1961) (J. Agric. Food Chem. 9 (1961) 301) Batch method was modified and adapted to FIA conditions. The formation kinetic of the 2,4-dinitrophenylhydrazine (DNPH)-pyruvate complex was evaluated at room temperature and at 37 degrees C. It was demonstrated the suitability of the chromopher formation at room temperature. The optimal values for the FIA parameters were: sample injection volume 3mL, flow rate 6mLmin(-1), reactor length 1.5m, sodium hydroxide concentration 1.0molL(-1) and hydrochloric acid concentration 0.5molL(-1). The working calibration range was extended from 80mgL(-1) (Batch method) to 700mgL(-1) with the FIA set up. The sample dilution step is thus avoided, simplifying the whole analysis process. The pungency in representative samples of the cultivars Yellow granex 438, Ultra Hybrid and Red onion "Sangre de Toro" was evaluated by the flow injection analysis (FIA)-pyruvate method and the results were compared to the reference Batch pyruvate method and to the taste panel test. Non-significant differences were found at the 95% of confidence level between the FIA method and the Batch reference method. Correlation coefficient when comparing the FIA results to the taste panel test was r(2) = 0.8353. Significant differences (P pungency of the cultivars, the Ultra Hybrid having the highest pungency. The pungency order from minor to major was: Red onion, Texas Grano 438 and Ultra Hybrid.

  8. Center for Environmental Kinetics Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bandstra, Joel Z.; Burgos, William D.; Peyton, Brent M.

    2006-04-05

    Over the past two decades, numerous studies have produced high quality information on the rates at which bacteria can reduce metal oxides. The prototypical study--such as the one depicted to the right--focuses on only a few of the myriad variables affecting the rate. This approach allows for effective dissection of the mechanisms underlying DMRB activity, but, it also produces disjoint information that must be synthesized if we hope to predict the behavior of bacteria at the systems level.

  9. Location Problem of Air Materials Supply Center for Air Force

    Institute of Scientific and Technical Information of China (English)

    王涛; 何亚群; 陶学禹

    2002-01-01

    Based on the analysis of three influencing factors on the air material supply center location, the location model of air material supply center was established. By solving the model, the rational supply center of air materials was also determined.

  10. RESULTS OF THE INTERNATIONAL INTERLABORATORY COMPARISON OF MGMT PROMOTER METHYLATION ANALYSIS INVOLVING TWENTY-THREE ACADEMIC CENTERS IN GERMANY, AUSTRIA AND THE NETHERLANDS

    Science.gov (United States)

    Reifenberger, Guido; Malzkorn, B.; Acker, T.; Bettstetter, M.; Buslei, R.; von Deimling, A.; Dietmaier, W.; Dubbink, H.J.; Eigenbrod, S.; Garvalov, B.K.; Gerstenmaier, U.; Giese, A.; Haase, D.; Hasselblatt, M.; Kirches, E.; Koch, A.; Marienfeld, R.; Mittelbronn, M.; Montesinos-Rongen, M.; Pagenstecher, A.; Riemenschneider, M.J.; Prinz, M.; Romeike, B.; Roos, A.; Spiegl-Kreinecker, S.; Schittenhelm, J.; Schlegel, J.; Thal, D.R.; Tops, B.B.J.; Weis, J.; Westphal, G.; Worm, K.; Felsberg, J.

    2014-01-01

    BACKGROUND: Molecular testing for MGMT promoter methylation has become of clinical importance in the diagnostic assessment of malignant gliomas since test results may guide therapeutic decision making, in particular in elderly patients with glioblastoma. However, the patterns and extent of MGMT promoter methylation may vary from tumor to tumor, and standardized approaches for its routine diagnostic assessment are lacking. Thus, external quality assessment (EQA) measures are required to ensure accuracy and reproducibility of results across different laboratories. METHODS: We performed an interlaboratory comparison of MGMT promoter methylation analysis involving twenty-three academic institutions in Germany, Austria and the Netherlands. Two different test rounds were carried out, the first one using high molecular weight DNA extracted from frozen tissue samples of 20 tumors and the second one using formalin-fixed paraffin-embedded tissue sections of 16 tumors. All samples were centrally retrieved from the CNS tumor tissue bank at Heinrich Heine University Düsseldorf. Each participating center evaluated the same set of samples using the locally established methods. Results were centrally collected, together with information on the individual assays and the number of tests carried out per year. RESULTS: Methylation specific-PCR was the most commonly used method at the participating centers. Other less common techniques included pyrosequencing of bisulfite-modified DNA, MethyQESD (methylation-quantification of endonuclease-resistant DNA), MLPA (Multiplex Ligation-dependent Probe Amplification), and PCR-based fragment analysis. MGMT testing results showed a good overall concordance across the participating laboratories for those tumors that either had strongly methylated or clearly unmethylated MGMT promoter sequences. However, poor concordance was obtained for cases with only weak or partial MGMT promoter methylation. CONCLUSIONS: Our study provides an overview of the

  11. Analysis of risk factors in elderly patients with purple urine bag syndrome: A retrospective analysis in a medical center in northern Taiwan

    Directory of Open Access Journals (Sweden)

    Tao-Chun Peng

    2014-01-01

    Full Text Available Background: Purple urine bag syndrome (PUBS, an uncommon phenomenon that turns urine tubes or bags purple or blue, can be encountered in long-term-care facilities. A thorough literature review shows that East Asia has a high incidence of PUBS. It is important to recognize the clinical features and risk factors of this phenomenon. The aim of this study is to explore the characteristics of patients with PUBS and correlate the onset of PUBS symptoms with risk factors. Materials and Methods: We reported nine cases of clinically confirmed PUBS between January 2009 and June 2013. Pertinent clinical information was collected, including age, feeding type, renal function, type of Foley catheter, urine analysis, and bacteriological data. Results: All of patients with PUBS presented with stable vital signs without evidence of clinical infection, such as fever or chills. The mean age of the patients was 86.6 ± 10.1 years, with a preponderance of females (77%. Five PUBS patients (55% had a history of chronic renal insufficiency. Six patients (66% had constipation. A logistic regression univariate analysis demonstrated a statistically significant urine pH in patients with PUBS [odds ratio (OR, 3.078; P = 0.036]. Risk factors, such as gender, were found to be significant using logistic regression multivariate analysis (OR, 0.031; P = 0.021. During the follow-up, all of the patients had Foley catheters re-inserted, and all of the patients received health education. Conclusion: The incidence of PUBS in the elderly population is associated with asymptomatic bacteriuria, urine pH, and gender but not renal function, type of feeding, or type of Foley catheter used. To understand PUBS and maintain urological hygiene, it is important to educate families and health care workers about PUBS and to recognize that PUBS is not regarded as a symptom of severe disease.

  12. Children's cancer centers

    Science.gov (United States)

    Pediatric cancer center; Pediatric oncology center; Comprehensive cancer center ... Treating childhood cancer is not the same as treating adult cancer. The cancers are different. So are the treatments and the ...

  13. Transplant Center Search Form

    Science.gov (United States)

    ... Share Your Story Give Us Feedback - A + A Transplant Center Search Form Welcome to the Blood & Marrow ... transplant centers for patients with a particular disease. Transplant Center login Username: * Password: * Request new password Join ...

  14. The Watergate Learning Center

    Science.gov (United States)

    Training in Business and Industry, 1971

    1971-01-01

    The Watergate Learning Center, recently opened by Sterling Learning Center in Washington, D. C., blueprints the plan established by Sterling and Marriott Hotels for a national chain of learning centers with much the same facilities. (EB)

  15. Hermes flight control center: Definition status

    Science.gov (United States)

    Letalle, Pierre

    1990-10-01

    The Hermes Flight Control Center (HFCC) located in Toulouse (France) is described. The center is the third in the world after the American center in Houston and the Soviet center in Kaliningrad. All the Hermes elements, both on board and on the ground will be coordinated by the HFCC for all phases of each mission. Aspects of the detailed definition phase still in the requirements analysis subphase are described. Diagrams are used to illustrate the interplay between the different systems.

  16. Prognostic value of the 7th AJCC/UICC TNM classification of noncardia gastric cancer: analysis of a large series from specialized Western centers.

    Science.gov (United States)

    Marrelli, Daniele; Morgagni, Paolo; de Manzoni, Giovanni; Coniglio, Arianna; Marchet, Alberto; Saragoni, Luca; Tiberio, Guido; Roviello, Franco

    2012-03-01

    To conduct a retrospective evaluation of the 7th-TNM classification of gastric cancer (GC) on a prospectively collected database. The recent TNM introduced relevant changes to GC classification. Data regarding 2090 consecutive patients with noncardia GC operated upon between 1991 and 2005 at 5 specialized centers were considered. The application of the new TNM was simulated, and its prognostic value was estimated. Relevant changes in stage distribution between 6th and 7th TNM were observed, mainly regarding the shift of a large proportion of cases from stages IB to IIA and from IIIA and IV to stages IIIB and IIIC. Cancer-related 10-year survival probability was 53% ± 1%. Different survival rates between new T (T2 vs. T3, P 15 involved lymph nodes; P TNM showed similar prognosis, whereas significant differences were observed among all other subgroups. The analysis of TNM categories within 7th TNM stages revealed nonhomogeneous survival rates in stages IIB, IIIB, and IV. The 7th AJCC/UICC TNM classification of noncardia GC identifies subgroups of patients with different prognosis. Stage distribution and stage-related survival changed notably from the 6th edition. Some improvements may be suggested from our data, with special reference to a higher prognostic weight of N status and the separation of N3a and N3b categories for stage grouping.

  17. Psychometric Limitations of the Center for Epidemiologic Studies-Depression Scale for Assessing Depressive Symptoms among Adults with HIV/AIDS: A Rasch Analysis

    Directory of Open Access Journals (Sweden)

    Caryl L. Gay

    2016-01-01

    Full Text Available The Center for Epidemiological Studies-Depression (CES-D scale is a widely used measure of depressive symptoms, but its psychometric properties have not been adequately evaluated among adults with HIV/AIDS. This study used an item response theory approach (Rasch analysis to evaluate the CES-D’s validity and reliability in relation to key demographic and clinical variables in adults with HIV/AIDS. A convenience sample of 347 adults with HIV/AIDS (231 males, 93 females, and 23 transgenders; age range 22–77 years completed the CES-D. A Rasch model application was used to analyze the CES-D’s rating scale functioning, internal scale validity, person-response validity, person-separation validity, internal consistency, differential item functioning (DIF, and differential test functioning. CES-D scores were generally high and associated with several demographic and clinical variables. The CES-D distinguished 3 distinct levels of depression and had acceptable internal consistency but lacked unidimensionality, five items demonstrated poor fit to the model, 15% of the respondents demonstrated poor fit, and eight items demonstrated DIF related to gender, race, or AIDS diagnosis. Removal of misfitting items resulted in minimal improvement in the CES-D’s substantive and structural validity. CES-D scores should be interpreted with caution in adults with HIV/AIDS, particularly when comparing scores across gender and racial groups.

  18. Predictors of malignancy in intraductal papillary mucinous neoplasm of the pancreas: analysis of 310 pancreatic resection patients at multiple high-volume centers.

    Science.gov (United States)

    Shimizu, Yasuhiro; Yamaue, Hiroki; Maguchi, Hiroyuki; Yamao, Kenji; Hirono, Seiko; Osanai, Manabu; Hijioka, Susumu; Hosoda, Waki; Nakamura, Yasushi; Shinohara, Toshiya; Yanagisawa, Akio

    2013-07-01

    The present study was a retrospective investigation of predictors of malignancy in intraductal papillary mucinous neoplasm (IPMN) of the pancreas. The subjects were 310 patients who underwent pancreatic resection at 3 high-volume centers. Preoperative laboratory and imaging findings were analyzed in logistic regression analyses. Endoscopic ultrasonography measurements were essential for the size of mural nodules, and a central review was conducted for pathological diagnosis. Pathological diagnosis was benign IPMN in 150 cases and malignant in 160 (noninvasive carcinoma, n = 100; invasive, n = 60). In multivariate analysis, size of mural nodules, diameter of main pancreatic duct, and cyst size of branch pancreatic duct were independent predictors of malignancy, and areas under the receiver operating characteristic curve for these 3 factors were 0.798, 0.643, and 0.601, respectively. With 7 mm taken as the cutoff value for the size of mural nodules, the diagnosis of malignant IPMN had sensitivity of 74.3% and specificity of 72.7%. Carcinoma without nodules was present in 15 patients (15/160 [9.4%]). The size of mural nodules measured with endoscopic ultrasonography showed high predictive ability. However, about 10% of carcinoma patients did not have nodules, and the handling of the diagnosis in such cases is a problem for the future.

  19. Adherence to the 2010 American College of Cardiology Foundation Appropriate Use Criteria for Cardiac Computed Tomography: Quality Analysis at a Tertiary Referral Center.

    Science.gov (United States)

    Sidhu, Manavjot S; Lumish, Heidi; Uthamalingam, Shanmugam; Engel, Leif-Christopher; Abbara, Suhny; Brady, Thomas J; Hoffmann, Udo; Ghoshhajra, Brian B

    2016-03-01

    In November 2010, the American College of Cardiology Foundation published revised appropriateness criteria (AC) for cardiac computed tomography (CT). We evaluated adherence to these criteria by providers of different subspecialties at a tertiary referral center. Reports of 383 consecutive patients who underwent clinically indicated cardiac CT from December 1, 2010, to July 31, 2011, were reviewed by physicians with appropriate training in cardiac CT. Scans were classified as appropriate, inappropriate, or uncertain based on the revised 2010 AC. Studies that did not fall under any of the specified indications were labeled as unclassified. Adherence to the AC was also analyzed as a function of provider type. Research scans were excluded from this analysis. Three hundred eight exams (80%) were classified as appropriate; 26 (7%), as inappropriate; 30 (8%), as uncertain; and 19 (5%), as unclassified. Of the 19 (5%) unclassified cardiac CT exams, the most common indication was for evaluation of suspected aortic dissection. Three hundred five exams (80%) were referred by cardiologists; 73 (19%), by internists; and 5 (1%), by neurologists. Of the 305 cardiology-referred studies, 221 (73%) were ordered by general cardiologists; 28 (9%), by interventional cardiologists; and 56 (19%), by electrophysiologists. There was no significant difference in adherence to the criteria between provider specialties or between cardiology subspecialties (P > 0.05). high across provider specialties.

  20. Analysis on US Engineering Research Centers Program-Development and Model%美国工程研究中心发展及模式分析

    Institute of Scientific and Technical Information of China (English)

    柳春; 夏迪; 王健

    2014-01-01

    Engineering Research Centers Programme (ERCs)is launched by US government in 1 985 within the framework of National Science Foundation in order to achieve three important goals:promoting inter-discipline engineering research, enhancing the national competition ability and educating engineering students. Based on the basic analysis method of na-tional science and technology planning,this paper discusses the background for developing ERCs and its strategic position.It also analyses ERCs basic management model,and its impact on US ERCs through 27 years development.%美国工程研究中心是美国政府为了整合大学工程研究能力、提高产品竞争力、加强工程技术人才培养,于1985年在国家科学基金(NSF)下设立的项目。运用国家科技计划的分析方法,论述美国工程研究中心的产生背景和战略定位,概括分析美国工程研究中心的基本管理模式,最后总结回顾美国工程研究中心27年的发展,阐明其对美国产业、经济的影响。

  1. Analysis of the lettuce data from the variable pressure growth chamber at NASA Johnson Space Center: A three-stage nested design model

    Science.gov (United States)

    Lee, Tze-San

    1992-01-01

    A model of three-stage nested experimental design was applied to analyze the lettuce data obtained from the variable pressure growth chamber test bed at NASA-Johnson Space Center. From the results of an application of the analysis of variance and covariance on the data set, it was noted that all of the (uncontrollable) factors, Side, Zone, Height and (controllable) PAR (photosynthetically active radiation), had nonhomogeneous effects on the dry weight of the edible biomass of lettuce per pot. Incidentally, the variations accountable to the (uncontrollable) factorial heterogeneities are merely 9 percent and 17 percent of the total variation for both the first and second crop test, respectively. After adjusting for the PAR as a covariate in the no-intercept model, the accountable variations to all the four factors are 94 percent and 92 percent for the first and the second crop test, respectively. With the use of a no-intercept simple linear regression model, the accountable variations to the factor PAR are 92 percent and 90 percent for the first and the second crop test, respectively. Evidently, the (controllable) factor PAR is the dominating one.

  2. Multi-center analysis of the effect of T-cell acute lymphoblastic leukemia subtype and minimal residual disease on allogeneic stem cell transplantation outcomes.

    Science.gov (United States)

    Brammer, J E; Saliba, R M; Jorgensen, J L; Ledesma, C; Gaballa, S; Poon, M; Maziarz, R T; Champlin, R E; Hosing, C; Kebriaei, P

    2017-01-01

    This study aims to provide a detailed analysis of allogeneic stem cell transplantation (allo-SCT) outcomes in a large T-cell acute lymphoblastic leukemia (T-ALL) cohort with a specific emphasis on the effects of pre-transplant minimal residual disease (MRD) and disease subtype, including the aggressive early-thymic precursor (ETP) subtype. Data from 102 allo-SCT patients with a diagnosis of T-ALL from three centers were retrospectively analyzed. Patients were grouped into four T-ALL subtypes: ETP, early, cortical and mature. At 3 years, overall survival (OS), PFS, non-relapse mortality and cumulative incidence (CI) progression were 35, 33, 11 and 55%, respectively. Patients transplanted in first complete remission (CR1) had a 3-year OS of 62% versus those transplanted in CR2 or greater (24%) (hazards ratio 1.6, P=0.2). Patients with MRD positivity at the time of transplant had significantly higher rates of progression compared with those with MRD negativity (76 vs 34%, hazards ratio 2.8, P=0.006). There was no difference in OS, PFS or cumulative incidence (CI) progression between disease subtypes, including ETP (n=16). ETP patients transplanted in CR1 (n=10) had OS of 47%, comparable to other disease subtypes, suggesting that allo-SCT can overcome the poor prognosis associated with ETP. MRD status at transplant was highly predictive of disease relapse, suggesting novel therapies are necessary to improve transplant outcomes.

  3. Cyclosporine treatment for Stevens-Johnson syndrome/toxic epidermal necrolysis: Retrospective analysis of a cohort treated in a specialized referral center.

    Science.gov (United States)

    Lee, Haur Yueh; Fook-Chong, Stephanie; Koh, Hong Yi; Thirumoorthy, Tharmotharampillai; Pang, Shiu Ming

    2017-01-01

    Treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) remains controversial. We sought to evaluate the impact of cyclosporine on hospital mortality in patients with SJS/TEN. All patients with SJS and TEN admitted to our center from 2011 to 2014 were treated under a standardized protocol that allowed for cyclosporine therapy if the inclusion and exclusion criteria were met. Clinical data were reviewed retrospectively. Comparative analysis was made on mortality outcomes with patients treated with cyclosporine versus what was expected based on SCORTEN. In all, 44 patients were admitted during the study period. A total of 24 patients received cyclosporine and the remaining 20 patients were treated supportively. SCORTEN predicted 7.2 deaths and 3 were observed in the group treated with cyclosporine. In the group treated supportively, SCORTEN predicted 5.9 deaths and 6 deaths were observed. The standardized mortality ratio of SJS/TEN treated with cyclosporine was 0.42 (95% confidence interval 0.09-1.22). Small sample size, retrospective design, and referral bias are limitations. The use of cyclosporine may improve mortality in SJS/TEN and needs to be validated in controlled studies. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  4. Simulation modeling analysis of sequential relations among therapeutic alliance, symptoms, and adherence to child-centered play therapy between a child with autism spectrum disorder and two therapists.

    Science.gov (United States)

    Goodman, Geoff; Chung, Hyewon; Fischel, Leah; Athey-Lloyd, Laura

    2017-07-01

    This study examined the sequential relations among three pertinent variables in child psychotherapy: therapeutic alliance (TA) (including ruptures and repairs), autism symptoms, and adherence to child-centered play therapy (CCPT) process. A 2-year CCPT of a 6-year-old Caucasian boy diagnosed with autism spectrum disorder was conducted weekly with two doctoral-student therapists, working consecutively for 1 year each, in a university-based community mental-health clinic. Sessions were video-recorded and coded using the Child Psychotherapy Process Q-Set (CPQ), a measure of the TA, and an autism symptom measure. Sequential relations among these variables were examined using simulation modeling analysis (SMA). In Therapist 1's treatment, unexpectedly, autism symptoms decreased three sessions after a rupture occurred in the therapeutic dyad. In Therapist 2's treatment, adherence to CCPT process increased 2 weeks after a repair occurred in the therapeutic dyad. The TA decreased 1 week after autism symptoms increased. Finally, adherence to CCPT process decreased 1 week after autism symptoms increased. The authors concluded that (1) sequential relations differ by therapist even though the child remains constant, (2) therapeutic ruptures can have an unexpected effect on autism symptoms, and (3) changes in autism symptoms can precede as well as follow changes in process variables.

  5. [Care for elderly patients in Africa: Analysis of the financial implications of the SESAME plan on the budget of the regional hospital center in Thies, Senegal].

    Science.gov (United States)

    Faye, A; Diousse, P; Seck, I; Diongue, M; Ndiaye, P; Diagne-Camara, M; Tal-Dia, A; Dia, La

    2010-04-01

    The SESAME plan has been implemented at the Thies Regional Hospital Center (TRHC) for one year. The purpose of this study was to analyze the financial implications of the plan on the hospital budget for the sustainability of care for persons aged 60 and over. This descriptive study included analysis of budget data from October 2006 to September 2007 plus information obtained by interviewing the accountant and head of SESAME plan. The number of patients managed, sources of CHRT funding, grants from various SESAME plan partners, and expenditures for each partner were determined. The weight of the SESAME plan in the CHRT operating budget was determined by calculating the ratio of the overall cost of care for elderly persons in relation to the hospital's revenues and SESAME grants. During the study period, the CHRT received a total of 17375 elderly persons including 89% with no pension or social security. The institute pension scheme (IPRES) covered 21% of the plan as compared to 79% for the state. Utilization plan grants in relation to funding source was 41% for IPRES and 124% for the State. The total cost of services provided to beneficiaries of the SESAME plan exceeded the aggregate amount by 26 083 847 CFA francs. The weight of the SESAME plan in the operating cost of the CHRT was 17%. Prefinancing a plan to cover elderly care in hospitals should be sufficient to prevent deficits from impacting negatively on the operating budget of the hospital.

  6. Cost-effectiveness analysis of darbepoetin after switch from epoetin-beta in patients on hemodialysis: an Italian single-center retrospective study

    Directory of Open Access Journals (Sweden)

    Mario Eandi

    2006-03-01

    Full Text Available Darbepoetin (DARB, a human erythropoietin with improved pharmacological parameters (longer half life and a dose-response relationship independent from the route of administration is a new treatment option for chronic nephropathy-induced anemia that in many Italian dialysis centers is substituting older erythropoietins, mainly due to greater ease of use. At current prices and at the theoretical and recommended 200:1 dose conversion factor, DARB pharmaceutical cost ranges from –9% to +17% of EPO cost. In this monocentric study, real drug consumption and related actual costs of a pre-switch semester with EPO were analysed and compared to the first two post-switch semesters with DARB therapy. Furthermore, erythropoetic response was recorded and related to drug exposition levels, in order to establish a real life EPO:DARB dose conversion factor. In this experience, the conversion factor was estimated in at least 250-280:1, depending on the method adopted for the estimation. The initial dose, chosen on the basis of the recommended conversion factor, induced an excessive erythropoietic response, which was generally followed by a dose reduction and successive titration to target desired Hb levels, generating the spiraliform dose-response curve associated with delayed feed-back mechanisms. The pharmacoeconomical analysis, conducted in the perspective of the public health service, indicated that the choice of substituting DARB for EPO in the treatment of chronic kidney failure-associated anemia is univocally convenient, the former being less costly and more effective.

  7. Southern California Particle Center

    Data.gov (United States)

    Federal Laboratory Consortium — At the Southern California Particle Center, center researchers will investigate the underlying mechanisms that produce the health effects associated with exposure to...

  8. Womens Business Center

    Data.gov (United States)

    Small Business Administration — Women's Business Centers (WBCs) represent a national network of nearly 100 educational centers throughout the United States and its territories, which are designed...

  9. Vicinal 1H-1H NMR coupling constants from density functional theory as reliable tools for stereochemical analysis of highly flexible multichiral center molecules.

    Science.gov (United States)

    López-Vallejo, Fabian; Fragoso-Serrano, Mabel; Suárez-Ortiz, Gloria Alejandra; Hernández-Rojas, Adriana C; Cerda-García-Rojas, Carlos M; Pereda-Miranda, Rogelio

    2011-08-05

    A protocol for stereochemical analysis, based on the systematic comparison between theoretical and experimental vicinal (1)H-(1)H NMR coupling constants, was developed and applied to a series of flexible compounds (1-8) derived from the 6-heptenyl-5,6-dihydro-2H-pyran-2-one framework. The method included a broad conformational search, followed by geometry optimization at the DFT B3LYP/DGDZVP level, calculation of the vibrational frequencies, thermochemical parameters, magnetic shielding tensors, and the total NMR spin-spin coupling constants. Three scaling factors, depending on the carbon atom hybridizations, were found for the (1)H-C-C-(1)H vicinal coupling constants: f((sp3)-(sp3)) = 0.910, f((sp3)-(sp2)) = 0.929, and f((sp2)-(sp2))= 0.977. A remarkable correlation between the theoretical (J(pre)) and experimental (1)H-(1)H NMR (J(exp)) coupling constants for spicigerolide (1), a cytotoxic natural product, and some of its synthetic stereoisomers (2-4) demonstrated the predictive value of this approach for the stereochemical assignment of highly flexible compounds containing multiple chiral centers. The stereochemistry of two natural 6-heptenyl-5,6-dihydro-2H-pyran-2-ones (14 and 15) containing diverse functional groups in the heptenyl side chain was also analyzed by application of this combined theoretical and experimental approach, confirming its reliability. Additionally, a geometrical analysis for the conformations of 1-8 revealed that weak hydrogen bonds substantially guide the conformational behavior of the tetraacyloxy-6-heptenyl-2H-pyran-2-ones.

  10. Diagnostic Utility of Pleural Fluid Cell Block versus Pleural Biopsy Collected by Flex-Rigid Pleuroscopy for Malignant Pleural Disease: A Single Center Retrospective Analysis

    Science.gov (United States)

    Sasada, Shinji; Izumo, Takehiro; Matsumoto, Yuji; Tsuchida, Takaaki

    2016-01-01

    Background Some trials recently demonstrated the benefit of targeted treatment for malignant disease; therefore, adequate tissues are needed to detect the targeted gene. Pleural biopsy using flex-rigid pleuroscopy and pleural effusion cell block analysis are both useful for diagnosis of malignancy and obtaining adequate samples. The purpose of our study was to compare the diagnostic utility between the two methods among patients with malignant pleural disease with effusion. Methods Data from patients who underwent flex-rigid pleuroscopy for diagnosis of pleural effusion suspicious for malignancy at the National Cancer Center Hospital, Japan between April 2011 and June 2014 were retrospectively reviewed. All procedures were performed under local anesthesia. At least 150 mL of pleural fluid was collected by pleuroscopy, followed by pleural biopsies from the abnormal site. Results Thirty-five patients who were finally diagnosed as malignant pleural disease were included in this study. Final diagnoses of malignancy were 24 adenocarcinoma, 1 combined adeno-small cell carcinoma, and 7 malignant pleural mesothelioma (MPM), and 3 metastatic breast cancer. The diagnostic yield was significantly higher by pleural biopsy than by cell block [94.2% (33/35) vs. 71.4% (25/35); p = 0.008]. All patients with positive results on cell block also had positive results on pleural biopsy. Eight patients with negative results on cell block had positive results on pleural biopsy (lung adenocarcinoma in 4, sarcomatoid MPM in 3, and metastatic breast cancer in 1). Two patients with negative results on both cell block and pleural biopsy were diagnosed was sarcomatoid MPM by computed tomography-guided needle biopsy and epithelioid MPM by autopsy. Conclusion Pleural biopsy using flex-rigid pleuroscopy was efficient in the diagnosis of malignant pleural diseases. Flex-rigid pleuroscopy with pleural biopsy and pleural effusion cell block analysis should be considered as the initial diagnostic

  11. Stereotactic Body Radiotherapy for Early-stage Non-small-cell Lung Cancer in Patients 80 Years and Older: A Multi-center Analysis.

    Science.gov (United States)

    Cassidy, Richard J; Patel, Pretesh R; Zhang, Xinyan; Press, Robert H; Switchenko, Jeffrey M; Pillai, Rathi N; Owonikoko, Taofeek K; Ramalingam, Suresh S; Fernandez, Felix G; Force, Seth D; Curran, Walter J; Higgins, Kristin A

    2017-09-01

    Stereotactic body radiotherapy (SBRT) is the standard of care for medically inoperable early-stage non-small-cell lung cancer. Despite the limited number of octogenarians and nonagenarians on trials of SBRT, its use is increasingly being offered in these patients, given the aging cancer population, medical fragility, or patient preference. Our purpose was to investigate the efficacy, safety, and survival of patients ≥ 80 years old treated with definitive lung SBRT. Patients who underwent SBRT were reviewed from 2009 to 2015 at 4 academic centers. Patients diagnosed at ≥ 80 years old were included. Kaplan-Meier and multivariate logistic regression and Cox proportional hazard regression analyses were performed. Recursive partitioning analysis was done to determine a subgroup of patients most likely to benefit from therapy. A total of 58 patients were included, with a median age of 84.9 years (range, 80.1-95.2 years), a median follow-up time of 19.9 months (range, 6.9-64.9 months), a median fraction size of 10.0 Gy (range, 7.0-20.0 Gy), and a median number of fractions of 5.0 (range, 3.0-8.0 fractions). On multivariate analysis, higher Karnofsky performance status (KPS) was associated with higher local recurrence-free survival (hazard ratio [HR], 0.92; P patients with KPS ≥ 75 had improved 3-year cancer-specific and overall survival (99.4% and 91.9%, respectively) compared with patients with KPS lung SBRT for early-stage non-small-cell lung cancer was efficacious and safe in patients ≥ 80 years old. Patients with a KPS of ≥ 75 derived the most benefit from therapy. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Production System Analysis of Brem Processing Unit (Case Study: The Industrial Centers of Brem in Kaliabu and Bancong Village, Madiun District

    Directory of Open Access Journals (Sweden)

    Ardaneswari Dyah Pitaloka Citraresmi

    2014-10-01

    Full Text Available The purpose of this study was to determine the condition, the priorities, and the strategy development policy of the brem Madiun production system as an effort to increase the brem Madiun production system. The samples which are used were the brem industries at industrial centers of brem in Kaliabu and Bancong Village at Madiun District. The main instrument to collect the data was a questionnaire for 21 respondents of business leaders. Data analysis method which is used was Analytical Hierarchy Process (AHP. The results showed that the sequence of factors causing the decline of brem’s production capacity were the final product (0,477, capital (0,244, raw materials (0,123, human resources (0,088, the tools and machinery (0,041, and the method (0,026. Benchmarks for goals to be achieved by the production system were the effectiveness of brem Madiun (0,548, productivity (0,227, efficiency (0,138, and quality (0,087. Strategies that can be done on developing the brem industry in Madiun are provision of venture capital to support the administrations, improvement of licensing services, improvement of joint venture accessibility on infrastructure production, supporting on marketing, improvement of human resources quality (coaching and training, development of product, improvement of business management, and development on network of business partnership respectively. After the several strategies development policy was formulated based on existing condition, then the performance of the brem Madiun production system can be improved. Keywords : Brem, Production System Analysis, Strategy Formulation

  13. Defibrotide for Treatment of Severe Veno-Occlusive Disease in Pediatrics and Adults: An Exploratory Analysis Using Data from the Center for International Blood and Marrow Transplant Research.

    Science.gov (United States)

    Strouse, Christopher; Richardson, Paul; Prentice, Grant; Korman, Sandra; Hume, Robin; Nejadnik, Bijan; Horowitz, Mary M; Saber, Wael

    2016-07-01

    Veno-occlusive disease (VOD) is an early and serious complication of hematopoietic cell transplantation (HCT) that is associated with inferior survival, particularly when it is complicated by multiorgan failure (severe VOD). We evaluated the efficacy of defibrotide in the treatment of severe VOD using observational data from the Center for International Blood and Marrow Transplant Research (CIBMTR). Eight thousand three hundred forty-one patients treated by HCT between 2008 and 2011 were identified from the CIBMTR clinical database; 3.2% met criteria for VOD and 1.2% met criteria for severe VOD. Patients with a diagnosis of VOD as reported to the CIBMTR by their transplanting centers, who had no prior history of cirrhosis, and who had a maximum total bilirubin level > 2.0 mg/dL by day +100 post-HCT were selected for study. Severe VOD was defined as VOD occurring in the setting of renal impairment requiring dialysis or any noninfectious pulmonary abnormality. Patients with severe VOD were divided into 2 groups for analysis: those treated with defibrotide (n = 41) and those not treated with defibrotide (n = 55). Patients in the nondefibrotide group were older, were more likely to be male, were more likely to have a history of previous fungal infection, and had a higher proportion of clinically significant pre-existing disease or organ impairment. Survival rate at day +100 was 39% (95% CI, 24.8% to 54.3%) in patients receiving defibrotide and 30.9% (95% CI, 19.5% to 43.6%) in those not receiving defibrotide. Resolution rate of VOD at day +100 was 51% in the defibrotide group and 29% in the nondefibrotide group (difference, 22.1%; 95% CI, 2.6% to 42%). The results of our study are consistent with previously reported experiences with defibrotide, confirm the poor outcome of this syndrome, and suggest defibrotide is effective in the treatment of severe VOD.

  14. Real time stagger of electric network advanced analysis functions of a modern control center; Escalonamento em tempo real das funcoes avancadas de analise de rede eletrica de um moderno centro de controle

    Energy Technology Data Exchange (ETDEWEB)

    Zagari, Eduardo Nicola Ferraz

    1996-02-01

    This work presents two models for implementation of staggers for network analysis functions in real time for a control center. The methodology is described. Tests were performed in a electric power system of Campinas region, Sao Paulo sate - Southeast Brazil. Results are presented.

  15. Taiyuan Satellite Launch Center

    Institute of Scientific and Technical Information of China (English)

    LiuJie

    2004-01-01

    There are three major space launch bases in China, the Jiuquan Satellite Launch Center,the Taiyuan Satellite Launch Center and the Xichang Satellite Launch Center. All the three launch centers are located in sparsely populated areas where the terrain is even and the field of vision is broad. Security, transport conditions and the influence of the axial rotation

  16. Student Success Center Toolkit

    Science.gov (United States)

    Jobs For the Future, 2014

    2014-01-01

    "Student Success Center Toolkit" is a compilation of materials organized to assist Student Success Center directors as they staff, launch, operate, and sustain Centers. The toolkit features materials created and used by existing Centers, such as staffing and budgeting templates, launch materials, sample meeting agendas, and fundraising…

  17. Volume totalizers analysis of pipelines operated by TRANSPETRO National Operational Control Center; Analise de totalizadores de volume em oleodutos operados pelo Centro Nacional de Controle e Operacao da TRANSPETRO

    Energy Technology Data Exchange (ETDEWEB)

    Aramaki, Thiago Lessa; Montalvao, Antonio Filipe Falcao [Petrobras Transporte S.A. (TRANSPETRO), Rio de Janeiro, RJ (Brazil); Marques, Thais Carrijo [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil)

    2012-07-01

    This paper aims to present the results and methodology in the analysis of differences in volume totals used in systems such as batch tracking and leak detection of pipelines operated by the National Center for Operational Control (CNCO) at TRANSPETRO. In order to optimize this type of analysis, software was developed to acquisition and processing of historical data using the methodology developed. The methodology developed takes into account the particularities encountered in systems operated by TRANSPETRO, more specifically, by CNCO. (author)

  18. Telework centers as local development

    DEFF Research Database (Denmark)

    Lorentzen, Anne

    2013-01-01

    projects. A record of the development challenges of the two host municipalities Jammerbugt and Brønderslev, to contextualize the telework centers in the local context. And finally a preliminary analysis and discussion of the two telework centers in relation to their potential community benefits......This paper discusses the establishment of distant work centers as an element in local development strategies in rural areas with a particular view on two new telework centers in Region North Denmark Distant work is a phenomenon on the rise, due to the development of the internet on the one hand...... regardless of location, as long as there is access to internet. Not only firms, but individual labor is potentially liberated from the logic of physical location and proximity. Technically speaking ‘geography is dead’ and the clustering of new service jobs in big cities is no longer a technical necessity...

  19. Multiconfigurate character of the DX center and statistical analysis of transport data in Si-doped Al{sub x}Ga{sub 1-x}As

    Energy Technology Data Exchange (ETDEWEB)

    Triki, A.; Rziga Ouaja, F.; Selmi, A. [Dept. de Physique, Faculte des Sciences, Monastir (Tunisia); Mejri, H. [Dept. de Physique, Faculte des Sciences, Monastir (Tunisia)

    2001-10-01

    Two statistics are developed using the multiconfigurate character of the DX center to analyse donors in n-type Al{sub x}Ga{sub 1-x}As:Si. The first statistics is derived assuming that the conduction electrons arise exclusively from DX centers. The second statistics supposes the existence of shallow donors in addition to the deep DX center. Experimental Hall data, obtained in Al{sub x}Ga{sub 1-x}As:Si grown by metalorganic chemical vapor deposition, are interpreted using these statistical calculations. (orig.)

  20. Statistical Analysis of Model Data for Operational Space Launch Weather Support at Kennedy Space Center and Cape Canaveral Air Force Station

    Science.gov (United States)

    Bauman, William H., III

    2010-01-01

    The 12-km resolution North American Mesoscale (NAM) model (MesoNAM) is used by the 45th Weather Squadron (45 WS) Launch Weather Officers at Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS) to support space launch weather operations. The 45 WS tasked the Applied Meteorology Unit to conduct an objective statistics-based analysis of MesoNAM output compared to wind tower mesonet observations and then develop a an operational tool to display the results. The National Centers for Environmental Prediction began running the current version of the MesoNAM in mid-August 2006. The period of record for the dataset was 1 September 2006 - 31 January 2010. The AMU evaluated MesoNAM hourly forecasts from 0 to 84 hours based on model initialization times of 00, 06, 12 and 18 UTC. The MesoNAM forecast winds, temperature and dew point were compared to the observed values of these parameters from the sensors in the KSC/CCAFS wind tower network. The data sets were stratified by model initialization time, month and onshore/offshore flow for each wind tower. Statistics computed included bias (mean difference), standard deviation of the bias, root mean square error (RMSE) and a hypothesis test for bias = O. Twelve wind towers located in close proximity to key launch complexes were used for the statistical analysis with the sensors on the towers positioned at varying heights to include 6 ft, 30 ft, 54 ft, 60 ft, 90 ft, 162 ft, 204 ft and 230 ft depending on the launch vehicle and associated weather launch commit criteria being evaluated. These twelve wind towers support activities for the Space Shuttle (launch and landing), Delta IV, Atlas V and Falcon 9 launch vehicles. For all twelve towers, the results indicate a diurnal signal in the bias of temperature (T) and weaker but discernable diurnal signal in the bias of dewpoint temperature (T(sub d)) in the MesoNAM forecasts. Also, the standard deviation of the bias and RMSE of T, T(sub d), wind speed and wind