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Sample records for analgesia epidural durante

  1. The experience of labour with epidural analgesia

    DEFF Research Database (Denmark)

    Jepsen, Ingrid; Keller, Kurt Dauer

    2014-01-01

    of the epidural analgesia as high, in general, their satisfaction with labour is unchanged or even lower when epidural analgesia is used. Question: How do women experience being in labour with epidural analgesia, and what kind of midwifery care do they, consequently, need? Methods: A field study and semi......-structured interviews were conducted on a phenomenological basis. Nine nulliparous women were observed from initiation of epidural analgesia until birth of their baby. They were interviewed the day after the birth and again 2 months later. The involved midwives were interviewed 2–3 h after the birth. Findings......: Initiation of epidural analgesia can have considerable implications for women’s experience of labour. Two different types of emotional reactions towards epidural analgesia are distinguished, one of which is particularly marked by a subtle sense of worry and ambivalence. Another important finding refers...

  2. Análisis de la no elección de la analgesia epidural durante el trabajo de parto en las mujeres andaluzas: "la buena sufridora"

    Directory of Open Access Journals (Sweden)

    L. Biedma Velázquez

    2010-02-01

    Full Text Available Introducción: La analgesia epidural se ha popularizado en España, tanto en su conocimiento como en su uso, a lo largo de los últimos 20 años. La elección de esta técnica analgésica por parte de la futura madre durante el trabajo de parto y el parto en Andalucía es un derecho de la mujer que, explícitamente, sólo estará limitado por sus condiciones físicas y de salud y por los recursos disponibles en el hospital en el momento del parto. Esta elección pone en relación 2 elementos: por un lado, el componente cognitivo que establece la conveniencia o no de utilizar esta técnica según los valores, percepciones, cultura, etc. de la mujer y, por otro, el componente conductual, es decir, el uso o no de la técnica en cuestión, que dependerá además de la elección de la mujer de las condiciones anteriormente mencionadas. Objetivo: Analizar qué características definen a las mujeres que, aun pudiendo, deciden no utilizar analgesia epidural durante el parto en Andalucía. Material y métodos: Para ello se ha utilizado la información proporcionada por las mujeres ingresadas por parto en los hospitales del Sistema Sanitario Público de Andalucía, contenida en las encuestas anuales de satisfacción de usuarios del sistema de atención hospitalario en esta comunidad autónoma entre los años 2000 y 2007. Con esta información se ha realizado un análisis de segmentación jerárquica que tenía por objetivo analizar el perfil de las mujeres que rechazan esta técnica analgésica. Resultados: Las principales características que definen a las mujeres que rechazan la analgesia epidural durante el parto vienen dadas por su nivel educativo, nivel de ingresos y situación laboral. Conclusiones: Las características sociales, económicas y culturales que definen el rechazo, es decir, el "tipo" de mujer que rehúsa la epidural, coinciden con el esquema de "mujer tradicional" estudiado por otros autores (que se caracteriza por tener escasos

  3. Epidural analgesia during labor vs no analgesia: A comparative study

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    Wesam Farid Mousa

    2012-01-01

    Full Text Available Background: Epidural analgesia is claimed to result in prolonged labor. Previous studies have assessed epidural analgesia vs systemic opioids rather than to parturients receiving no analgesia. This study aimed to evaluate the effect of epidural analgesia on labor duration compared with parturients devoid of analgesia. Methods: One hundred sixty nulliparous women in spontaneous labor at full term with a singleton vertex presentation were assigned to the study. Parturients who request epidural analgesia were allocated in the epidural group, whereas those not enthusiastic to labor analgesia were allocated in the control group. Epidural analgesia was provided with 20 mL bolus 0.5% epidural lidocaine plus fentanyl and maintained at 10 mL for 1 h. Duration of the first and second stages of labor, number of parturients receiving oxytocin, maximal oxytocin dose required for each parturient, numbers of instrumental vaginal, vacuum-assisted, and cesarean deliveries and neonatal Apgar score were recorded. Results: There was no statistical difference in the duration of the active-first and the second stages of labor, instrumental delivery, vacuum-assisted or cesarean delivery rates, the number of newborns with 1-min and 5-min Apgar scores less than 7 between both groups and number of parturients receiving oxytocin, however, the maximal oxytocin dose was significantly higher in the epidural group. Conclusion: Epidural analgesia by lidocaine (0.5% and fentanyl does not prolong labor compared with parturients without analgesia; however, significant oxytocin augmentation is required during the epidural analgesia to keep up the aforementioned average labor duration.

  4. Analgesia epidural para parto en la gestante obesa Epidural analgesia for labour in obese patients

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    E. Guasch

    2006-10-01

    Full Text Available La obesidad es un problema global de salud en continuo aumento en el mundo desarrollado. Dado que la incidencia de la obesidad es mayor en mujeres que en hombres, los anestesiólogos con especial dedicación a la obstetricia, tendrán mayor oportunidad de enfrentarse a este tipo de pacientes. Nuestro objetivo es determinar la dificultad en la realización de la técnica epidural para analgesia de parto y analizar la incidencia de complicaciones ocurridas durante la punción en las gestantes obesas, así como evaluar la eficacia de la analgesia epidural en este grupo de pacientes en un estudio observacional retrospectivo de todos los bloqueos epidurales para analgesia de parto realizados en un hospital universitario de nivel 4 durante un periodo de cuatro años. Se ha estudiado un total de 13616 pacientes, clasificándolas según el índice de masa corporal en Kg./m² (IMC. En las pacientes no obesas (IMCObesity is an increasing global health problem in Developer countries. As its incidence is grater in women than men, obstetric anesthesiologists wil be envolved in the care of the obese patient more often. Our aim is to study punction dificulties in obese parturients requiring epidural analgesia for labor, and to compare punction complications between obese and non obese parturients as analgesic efficacy between obese and non obese patients in a retrospective observational study among all the epidural analgesic blocks performed in a universitary hospital in a four years period. We studied 13616 patients, who were classified according to body mass index in Kg/m² (BMI. In the non obese group patients (BMI<30; first attempt epidural success was achieved in 76,5%. Mild obese patients (BMI 30-32, severe obese (BMI 33-39 and morbid obese (BMI≥40, the percents were 69, 3%, 63,2% y 47,4% respectively. The comparison among obese and non obese patients was significati-vely different (p<0,001. Punction complications did not show differences among groups

  5. Epidural Analgesia in the Postoperative Period

    Science.gov (United States)

    2001-10-01

    epidurally. They are opiods and local anesthetics. The pharmacokinetics and pharmacodynamics of each class are different, and they may act...overall pharmacodynamics of the drug. Epidural Opioids Brown (2000) states that opioids are one class of drug that may be used for epidural analgesia...morphine with lidocaine or bupivacaine with the effects of these medications when administered alone in mice. They used various tests to measure

  6. Epidural anaesthesia and analgesia for liver resection.

    Science.gov (United States)

    Tzimas, P; Prout, J; Papadopoulos, G; Mallett, S V

    2013-06-01

    Although epidural analgesia is routinely used in many institutions for patients undergoing hepatic resection, there are unresolved issues regarding its safety and efficacy in this setting. We performed a review of papers published in the area of anaesthesia and analgesia for liver resection surgery and selected four areas of current controversy for the focus of this review: the safety of epidural catheters with respect to postoperative coagulopathy, a common feature of this type of surgery; analgesic efficacy; associated peri-operative fluid administration; and the role of epidural analgesia in enhanced recovery protocols. In all four areas, issues are raised that question whether epidural anaesthesia is always the best choice for these patients. Unfortunately, the evidence available is insufficient to provide definitive answers, and it is clear that there are a number of areas of controversy that would benefit from high-quality clinical trials.

  7. Effect of postoperative epidural analgesia on surgical outcome

    DEFF Research Database (Denmark)

    Holte, K; Holte, Kathrine

    2002-01-01

    Pain relief allowing sufficient mobilization after major surgical procedures can only be achieved by continuous epidural analgesia with local anesthetics, which also reduces the stress response to surgery. However, the role of postoperative epidural analgesia on postoperative morbidity is controv...

  8. [Epidural analgesia in combination with general anesthesia].

    Science.gov (United States)

    Gottschalk, Antje; Poepping, Daniel M

    2015-07-01

    Epidural anaesthesia is a widely used and accepted technique for perioperative analgesia in different kinds of surgery. Apart from analgetic effect and due to wide positve effects on patients outcome epidural analgesia is often used with general anaesthesia. It represents a reliable and reversible neural deafferentation technique that effectively contributes to a reduction of the surgical stress response with subsequent positive effects on cardiopulmonary, gastrointestinal, and immune function. Animal studies suggest that the use of epidural anaesthesia may be beneficial for cancer surgery because of less tumour recurrence. Further, a benefit is expected in patient's mortality. This article summarizes and critically discusses the current knowledge on the effects of epidural anaesthesia on pain management, cardiopulmonary as well as gastrointestinal functions and patient's outcome.

  9. Effect of postoperative epidural analgesia on surgical outcome

    DEFF Research Database (Denmark)

    Holte, K; Holte, Kathrine

    2002-01-01

    Pain relief allowing sufficient mobilization after major surgical procedures can only be achieved by continuous epidural analgesia with local anesthetics, which also reduces the stress response to surgery. However, the role of postoperative epidural analgesia on postoperative morbidity is controv......Pain relief allowing sufficient mobilization after major surgical procedures can only be achieved by continuous epidural analgesia with local anesthetics, which also reduces the stress response to surgery. However, the role of postoperative epidural analgesia on postoperative morbidity...... is controversial. We therefore update the effects of postoperative analgesia on surgical outcome. After major abdominal surgery, postoperative epidural analgesia with local anesthetics significantly reduces postoperative ileus and pulmonary complications while effects on cardiac morbidity are debatable. Continuous...... regimen does not contain a sufficient amount of local anesthetics. Future evaluation of the effects of epidural analgesia on postoperative outcome also requires integration of epidural analgesia within a multimodal rehabilitation programme....

  10. Análisis de la no elección de la analgesia epidural durante el trabajo de parto en las mujeres andaluzas: "la buena sufridora" Analysis of rejection of epidural analgesia during labor in Andalusian women: "the silent sufferer"

    Directory of Open Access Journals (Sweden)

    L. Biedma Velázquez

    2010-02-01

    Full Text Available Introducción: La analgesia epidural se ha popularizado en España, tanto en su conocimiento como en su uso, a lo largo de los últimos 20 años. La elección de esta técnica analgésica por parte de la futura madre durante el trabajo de parto y el parto en Andalucía es un derecho de la mujer que, explícitamente, sólo estará limitado por sus condiciones físicas y de salud y por los recursos disponibles en el hospital en el momento del parto. Esta elección pone en relación 2 elementos: por un lado, el componente cognitivo que establece la conveniencia o no de utilizar esta técnica según los valores, percepciones, cultura, etc. de la mujer y, por otro, el componente conductual, es decir, el uso o no de la técnica en cuestión, que dependerá además de la elección de la mujer de las condiciones anteriormente mencionadas. Objetivo: Analizar qué características definen a las mujeres que, aun pudiendo, deciden no utilizar analgesia epidural durante el parto en Andalucía. Material y métodos: Para ello se ha utilizado la información proporcionada por las mujeres ingresadas por parto en los hospitales del Sistema Sanitario Público de Andalucía, contenida en las encuestas anuales de satisfacción de usuarios del sistema de atención hospitalario en esta comunidad autónoma entre los años 2000 y 2007. Con esta información se ha realizado un análisis de segmentación jerárquica que tenía por objetivo analizar el perfil de las mujeres que rechazan esta técnica analgésica. Resultados: Las principales características que definen a las mujeres que rechazan la analgesia epidural durante el parto vienen dadas por su nivel educativo, nivel de ingresos y situación laboral. Conclusiones: Las características sociales, económicas y culturales que definen el rechazo, es decir, el "tipo" de mujer que rehúsa la epidural, coinciden con el esquema de "mujer tradicional" estudiado por otros autores (que se caracteriza por tener escasos

  11. Neuraxial block and postoperative epidural analgesia

    DEFF Research Database (Denmark)

    Leslie, K; McIlroy, D; Kasza, J

    2016-01-01

    BACKGROUND: We assessed associations between intraoperative neuraxial block and postoperative epidural analgesia, and a composite primary outcome of death or non-fatal myocardial infarction, at 30 days post-randomization in POISE-2 Trial subjects. METHODS: 10 010 high-risk noncardiac surgical pat...

  12. Effect of postoperative epidural analgesia on surgical outcome

    DEFF Research Database (Denmark)

    Holte, K; Holte, Kathrine

    2002-01-01

    epidural analgesia significantly lowers the risk of thromboembolic complications after lower body procedures, while no effect is seen after major abdominal surgery. Unfortunately, many studies have inadequate study design, with use of lumbar epidural analgesia for abdominal procedures, or the epidural...

  13. Recent Advances in Epidural Analgesia

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    Maria Bauer

    2012-01-01

    Full Text Available Neuraxial anesthesia is a term that denotes all forms of central blocks, involving the spinal, epidural, and caudal spaces. Epidural anesthesia is a versatile technique widely used in anesthetic practice. Its potential to decrease postoperative morbidity and mortality has been demonstrated by numerous studies. To maximize its perioperative benefits while minimizing potential adverse outcomes, the knowledge of factors affecting successful block placement is essential. This paper will provide an overview of the pertinent anatomical, pharmacological, immunological, and technical aspects of epidural anesthesia in both adult and pediatric populations and will discuss the recent advances, the related rare but potentially devastating complications, and the current recommendations for the use of anticoagulants in the setting of neuraxial block placement.

  14. Epidural Analgesia and Fever at Labor

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    Ye. M. Shifman

    2008-01-01

    Full Text Available Objective: to study the incidence of labor fever under epidural analgesia (EA and to evaluate its impact on the courses of puerperium and early neonatality. Subjects and methods. The paper presents the data of a prospective study of the course of labor, puerperium, and early neonatality in 397 women in whom labors occurred at the Republican Peritoneal Center in 2006. A study group included 324 parturients in whom labor pain was relieved by EA. A comparison group comprised 55 parturients in whom no analgesics were used at labor. Results. There were no significant statistical differences between the groups in the incidence of labor fever and complicated puerperium and in that of neonatal pyoseptic diseases. Key words: labor hyperthermia, epidural analgesia, labor pain relief.

  15. [Maternal postures and epidural analgesia during labour].

    Science.gov (United States)

    Ducloy-Bouthors, A-S; De Gasquet, B; Davette, M; Cuisse, M

    2006-06-01

    The evolution of birth is of interest for obstetricians and midwives. Postures with asymmetric stretching and balance, kneeling, or sitting have been claimed to be able to help foetal head rotation. Although walking during labour have no influence on the outcome of labour, hip-flexed postures enlarging the pelvic diameter are yet evaluated to improve the obstetric course of labour. In a prospective randomised study including 93 parturients, we compared the supine 30 degrees lateral tilt (control group) to three hip-flexed postures: sitting (S), right hip-flexed left lateral position (L) and left hip-flexed right lateral position (R). Epidural analgesia with 12 ml ropivacaine 0.1% and sufentanil 0.5 microg/ml was administered over a period of six minutes. The total epidural spread was 15+/-0.3 dermatomes and the upper level of thermo-analgesic blockade reached T7-T8 (T5 to T10) in each group. There were no differences between groups for the left and right total spread and upper level of epidural blockade, for the time to maximal block and pain relief. There was no motor block and no maternal or foetal side effects. We conclude that, for the three hip-flexed postures tested, position does not influence local anesthetic spread or symmetry of analgesia after induction of obstetric epidural anaesthesia.

  16. Single dose spinal analgesia: Is it a good alternative to epidural analgesia in controlling labour pain?

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    Tarek AbdElBarr

    2014-07-01

    Conclusions: Based on the results of our study we concluded that single dose spinal analgesia is a good alternative to epidural analgesia in controlling labour pain i.e. spinal compared to epidural is more easy performed, faster, less expensive, and provide effective analgesia.

  17. OUR EXPERIENCE WITH EPIDURAL LABOUR ANALGESIA

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    Uršula Reš Muravec

    2003-12-01

    Full Text Available Background. To evaluate the effects of regional labour analgesia used at the Hospital for Gynecology and Obstetrics in Postojna, Slovenia, in the year 2002.Patients and methods. In this retrospective study we enrolled 294 parturients who delivered in the year 2002 in the Postojna Maternity Hospital: in group 1 there were 147 parturients in whom three different regional analgesic techniques (study group were used at labour; in group 2 there were 147 parturients in whom regional analgesia was not used (control group. In the first step the two groups were compared in terms of maternal demographic data, duration and outcome of labour and 1' and 5' Apgar scores. In the second step the three regional analgesic groups were compared in terms of the course and outcome of labour, fetal condition, side and adverse effects of regional analgesic techniques, and patient satisfaction with a particular analgesic technique.Results. Regional labour analgesia was used in 147 (14% of the 1048 women who delivered in 2002: epidural analgesia (EPI was performed in 51.0%, combined spinal-epidural (CSE in 42.2% and spinal analgesia (SA in 6.8% of cases. The women in the regional analgesia group were significantly older, more educated, more often nulliparous and accompanied by their partner at labour than the women in the control group. Further, the duration of labour was significantly longer, oxytocin more frequently administered than in the control group. In terms of labour outcome there were no differences in the Cesarean section rates and 1- and 5-min Apgar scores minutes, but and the vacuum extraction rate was significantly higher in the regional analgesia group. Among the three regional analgesia techniques used, there were no statistically significant differences observed in terms of labour duration and outcome, and Apgar scores. The patient satisfaction was greatest with CSE. Adverse side effects such as weak muscles, reduced motion abilities, itching, nausea

  18. Difficulty in the removal of epidural catheter for labor analgesia

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    Mohamed S Hajnour

    2017-01-01

    Full Text Available For labor pain management epidural analgesia is a popular and an effective method. Difficult removal of epidural catheters occasionally occurs, and several maneuvers have been recommended. The purpose of this article is to raise awareness of the problem of retained epidural catheter fragments and identify the potential impact of complications.

  19. Difficulty in the removal of epidural catheter for labor analgesia.

    Science.gov (United States)

    Hajnour, Mohamed S; Khokhar, Rashid Saeed; Ejaz, Abdul Aziz Ahmed; Al Zahrani, Tariq; Kanchi, Naveed Uddin

    2017-01-01

    For labor pain management epidural analgesia is a popular and an effective method. Difficult removal of epidural catheters occasionally occurs, and several maneuvers have been recommended. The purpose of this article is to raise awareness of the problem of retained epidural catheter fragments and identify the potential impact of complications.

  20. The experience of giving birth with epidural analgesia.

    Science.gov (United States)

    Jepsen, Ingrid; Keller, Kurt Dauer

    2014-06-01

    There is a lack of literature about what constitutes good midwifery care for women who have epidural analgesia during labour. It is known that an increasing number of women receive epidural analgesia for labour pain. We also know that while women rate the painkilling effect of the epidural analgesia as high, in general, their satisfaction with labour is unchanged or even lower when epidural analgesia is used. How do women experience being in labour with epidural analgesia, and what kind of midwifery care do they, consequently, need? A field study and semi-structured interviews were conducted on a phenomenological basis. Nine nulliparous women were observed from initiation of epidural analgesia until birth of their baby. They were interviewed the day after the birth and again 2 months later. The involved midwives were interviewed 2-3h after the birth. Initiation of epidural analgesia can have considerable implications for women's experience of labour. Two different types of emotional reactions towards epidural analgesia are distinguished, one of which is particularly marked by a subtle sense of worry and ambivalence. Another important finding refers to the labouring woman's relationship with the midwife, which represents an essential influencing factor on the woman' experience of labour. Within this relationship, some rather unnoticed matters of communication and recognition appear to be of decisive significance. After initiation of epidural analgesia the requirements of midwifery care seem to go beyond how women verbalise and define their own needs. The midwife should be attentive to the labouring woman's type of emotional reaction to epidural analgesia and her possible intricate worries. Copyright © 2014 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  1. Patient controlled analgesia with remifentanil versus epidural analgesia in labour : randomised multicentre equivalence trial

    NARCIS (Netherlands)

    Freeman, Liv M; Bloemenkamp, Kitty W; Franssen, Maureen T; Papatsonis, Dimitri N; Hajenius, Petra J; Hollmann, Markus W; Woiski, Mallory D; Porath, Martina; van den Berg, Hans J; van Beek, Erik; Borchert, Odette W H M; Schuitemaker, Nico; Sikkema, J Marko; Kuipers, A H M; Logtenberg, Sabine L M; van der Salm, Paulien C M; Oude Rengerink, Katrien; Lopriore, Enrico; van den Akker-van Marle, M Elske; le Cessie, Saskia; van Lith, Jan M; Struys, Michel M; Mol, Ben Willem J; Dahan, Albert; Middeldorp, Johanna M; Oude Rengerink, K

    2015-01-01

    OBJECTIVE: To determine women's satisfaction with pain relief using patient controlled analgesia with remifentanil compared with epidural analgesia during labour. DESIGN: Multicentre randomised controlled equivalence trial. SETTING: 15 hospitals in the Netherlands. PARTICIPANTS: Women with an interm

  2. Labour pain with remifentanil patient-controlled analgesia versus epidural analgesia : a randomised equivalence trial

    NARCIS (Netherlands)

    Logtenberg, Slm; Oude Rengerink, K; Verhoeven, C J; Freeman, L M; van den Akker, Esa; Godfried, M B; van Beek, E; Borchert, Owhm; Schuitemaker, N; van Woerkens, Ecsm; Hostijn, I; Middeldorp, J M; van der Post, J A; Mol, B W

    OBJECTIVE: To distinguish satisfaction with pain relief using remifentanil patient-controlled analgesia (RPCA) compared with epidural analgesia (EA) in low-risk labouring women. DESIGN: Randomised controlled equivalence trial. SETTING: Eighteen midwifery practices and six hospitals in the

  3. Epidural analgesia in cattle, buffalo, and camels

    Directory of Open Access Journals (Sweden)

    Zuhair Bani Ismail

    2016-12-01

    Full Text Available Epidural analgesia is commonly used in large animals. It is an easy, cheap, and effective technique used to prevent or control pain during surgeries involving the tail, anus, vulva, perineum, caudal udder, scrotum, and upper hind limbs. The objectives of this article were to comprehensively review and summarize all scientific data available in the literature on new techniques and drugs or drug combinations used for epidural anesthesia in cattle, camel, and buffalo. Only articles published between 2006 and 2016 were included in the review. The most common sites for epidural administration in cattle, camels, and buffalos were the sacrococcygeal intervertebral space (S5-Co1 and first intercoccygeal intervertebral space (Co1-Co2. The most frequently used drugs and dosages were lidocaine (0.22-0.5 mg/kg, bupivacaine (0.125 mg/kg, ropivacaine (0.11 mg/kg, xylazine (0.05 mg/kg, medetomidine (15 μg/kg, romifidine (30-50 μg/kg, ketamine (0.3-2.5 mg/kg, tramadol (1 mg/kg, and neostigmine (10 μg/kg, and the clinical applications, clinical effects, recommendations, and side effects were discussed.

  4. Epidural analgesia in cattle, buffalo, and camels.

    Science.gov (United States)

    Ismail, Zuhair Bani

    2016-12-01

    Epidural analgesia is commonly used in large animals. It is an easy, cheap, and effective technique used to prevent or control pain during surgeries involving the tail, anus, vulva, perineum, caudal udder, scrotum, and upper hind limbs. The objectives of this article were to comprehensively review and summarize all scientific data available in the literature on new techniques and drugs or drug combinations used for epidural anesthesia in cattle, camel, and buffalo. Only articles published between 2006 and 2016 were included in the review. The most common sites for epidural administration in cattle, camels, and buffalos were the sacrococcygeal intervertebral space (S5-Co1) and first intercoccygeal intervertebral space (Co1-Co2). The most frequently used drugs and dosages were lidocaine (0.22-0.5 mg/kg), bupivacaine (0.125 mg/kg), ropivacaine (0.11 mg/kg), xylazine (0.05 mg/kg), medetomidine (15 µg/kg), romifidine (30-50 µg/kg), ketamine (0.3-2.5 mg/kg), tramadol (1 mg/kg), and neostigmine (10 µg/kg), and the clinical applications, clinical effects, recommendations, and side effects were discussed.

  5. Epidural analgesia in cattle, buffalo, and camels

    Science.gov (United States)

    Ismail, Zuhair Bani

    2016-01-01

    Epidural analgesia is commonly used in large animals. It is an easy, cheap, and effective technique used to prevent or control pain during surgeries involving the tail, anus, vulva, perineum, caudal udder, scrotum, and upper hind limbs. The objectives of this article were to comprehensively review and summarize all scientific data available in the literature on new techniques and drugs or drug combinations used for epidural anesthesia in cattle, camel, and buffalo. Only articles published between 2006 and 2016 were included in the review. The most common sites for epidural administration in cattle, camels, and buffalos were the sacrococcygeal intervertebral space (S5-Co1) and first intercoccygeal intervertebral space (Co1-Co2). The most frequently used drugs and dosages were lidocaine (0.22-0.5 mg/kg), bupivacaine (0.125 mg/kg), ropivacaine (0.11 mg/kg), xylazine (0.05 mg/kg), medetomidine (15 µg/kg), romifidine (30-50 µg/kg), ketamine (0.3-2.5 mg/kg), tramadol (1 mg/kg), and neostigmine (10 µg/kg), and the clinical applications, clinical effects, recommendations, and side effects were discussed. PMID:28096620

  6. Epidural analgesia for labour: maternal knowledge, preferences and informed consent.

    LENUS (Irish Health Repository)

    2012-02-29

    Epidural analgesia has become increasingly popular as a form of labour analgesia in Ireland. However obtaining true inform consent has always been difficult. Our study recruited 100 parturients who had undergone epidural analgesia for labour, aimed to determine the information they received prior to regional analgesia, and to ascertain their preferences regarding informed consent. Only 65 (65%) of patients planned to have an epidural. Knowledge of potential complications was variable and inaccurate, with less than 30 (30%) of women aware of the most common complications. Most women 79 (79%) believed that discomfort during labour affected their ability to provide informed consent, and believe consent should be taken prior to onset of labour (96, 96%). The results of this study helps define the standards of consent Irish patients expect for epidural analgesia during labour.

  7. How first time mothers experience the use of epidural analgesia

    DEFF Research Database (Denmark)

    Jepsen, Ingrid

    2010-01-01

    How first time mothers experience the use of epidural analgesia during birth Ingrid Jepsen, Midwife, SD, MPH, Kurt Dauer Keller cand.psych, PhD Contact email irj@ucn.dk Aim: to investigate the experiences of epidural analgesia as to the choice of epidurals, the changes in pain, the period from th...... midwives handle the epidurals. Conclusion: In particular, the use of an epidural does not diminish the need for an individual approach. The woman’s level of consciousness and the entire situation makes her very sensitive to the midwives care....... factors influencing the relationship with the midwives were: the very choice of an epidural, the midwives accept of that choice, satisfaction with the presence of the midwifes, the continuity of the process, and a high level of information. Clearly, the establishment of an epidural implies important...

  8. EPIDURAL ANALGESIA DURING LABOR Analgesia epidural para el trabajo de parto

    Directory of Open Access Journals (Sweden)

    Juan Carlos Zafra Pedone

    2008-12-01

    Full Text Available Introduction: The labor pain affect to all pregnant woman and it has biochemical and physiological changes that affect to mother and fetus and interact with your normal evolution. Currently there are analgesic techniques to less effectively labor pain, to provide a high satisfaction level and supply clinical and laboratory beneficial outcomes. In own context these techniques are very low used. Objective: To describe the use of epidural analgesic procedures in a pregnancy woman group during labor at the Universitarian Hospital San Jose – Popayan, Colombia. Materials and methods: Case series design. We recollected information of patients from Obstetric service during two months of 2006. The patient’s information was recollected from medical history with an instrument that content variables related with the analgesic technique and labor. The analyses were performed using descriptive statistics Results: 41 pregnant woman with a mean age of 23,4 were included. 65,9% were nulliparous and 85,4% were term pregnancy. At the moment of dural puncture the dilation and EVA pain scale mode was 6 and 8 respectively. The latency mean was 14,1 minutes. 95,1% were require a booster applied in a mean of 80 minutes and 61% were required a second booster applied in a mean of 49 min after that. The way of termination of pregnancy was vaginal predominantly. Conclusions: The results of this study are congruent to reporting in the world literature. These conclusions support the effectiveness of epidural analgesia and its favorable benefit/risk relation to the control of labor pain. Introducción: El dolor asociado con el trabajo de parto afecta a todas las pacientes e involucra alteraciones que afectan a la madre y al feto e interactúan interfiriendo con su evolución normal. Actualmente disponemos de alternativas analgésicas peridurales que han demostrado controlar en forma efectiva el dolor, proporcionar un alto grado de satisfacción de las pacientes y proveer

  9. COMPARISON OF PATIENT CONTROLLED EPIDURAL ANALGESIA WITH CONTINUOUS EPIDURAL INFUSION FOR LABOUR ANALGESIA

    Directory of Open Access Journals (Sweden)

    Sumaiah Tahseen

    2016-07-01

    Full Text Available We conducted a study to compare the efficacy and safety of Patient Controlled Epidural Analgesia (PCEA with that of Continuous Infusion of Epidural Analgesia (CIEA for maintenance of labour analgesia and evaluated the quality of analgesia and obstetric and safety outcomes. METHODS The study was a hospital-based prospective, randomised control trial on 80 parturients who had a normal antenatal period. Each parturient received 500-1000 mL lactated ringer solution Intravenously (IV prior to initiating epidural blockade. Epidural catheter placement was performed in a standard manner and all patients received an initial dose of 8-10 mL bupivacaine 0.25%. Parturients self-administered 0.125% bupivacaine with fentanyl 2.5 µg/mL using PCA pumps programmed as follows: 4 mL bolus with a 20 mins Lockout Interval (LI. Group B received CIEA of 8 mL 0.125% bupivacaine with fentanyl 2.5/mL. Hourly assessments included: VAS scores for pain and satisfaction, sensory and motor block, analgesic supplements, bupivacaine and fentanyl consumption. RESULTS Data from 80 patients showed no differences among groups in pain relief. Maternal satisfaction was greater in PCEA group. Anaesthetic interventions by way of supplemental doses of Bupivacaine and Fentanyl in the PCEA group were minimal (4 and 2 vs 25 and 12 P <0.001 compared to CEI group. PCEA group received less local anaesthetic (5.2 vs 9.4 p <0.001 and few patients in PCEA group had motor weakness compared to CEI group (6 vs 17 p <0.05. Both methods were safe for mother and newborn. CONCLUSION Patients who received PCEA required less anaesthetic interventions, required lower doses of local anaesthetic, fentanyl and have less motor weakness than those who received CEI.

  10. [Epidural obstetric analgesia, maternal fever and neonatal wellness parameters].

    Science.gov (United States)

    Fernández-Guisasola, J; Delgado Arnáiz, C; Rodríguez Caravaca, G; Serrano Rodríguez, M L; García del Valle, S; Gómez-Arnau, J I

    2005-04-01

    To study the relation between epidural analgesia and the development of maternal fever during labor and childbirth, and to determine the possible relation between that association and neonatal welfare and in the performance of tests to rule out sepsis in newborns. Prospective study of all women who gave birth at Fundación Hospital Alcorcón over a period of 3 years. All the women were offered epidural analgesia based on infusion of 0.0625% bupivacaine and 2 microg x mL(-1). Data collected were age, nulliparity, epidural analgesia infusion, induction of labor, uterine stimulation with oxytocin, type of birth, fetal weight, duration of dilation and expulsion, Apgar score (at 1 and 5 minutes), umbilical artery pH, and maternal temperature. Data for 4364 women were analyzed. Fever developed during labor in 5.7%; 93.7% of the fevers occurred in women receiving epidural analgesia (Pneonatal wellness parameters studied.

  11. Catheter failure rates and time course with epidural versus combined spinal-epidural analgesia in labor.

    Science.gov (United States)

    Groden, J; Gonzalez-Fiol, A; Aaronson, J; Sachs, A; Smiley, R

    2016-05-01

    The combined spinal-epidural technique for labor analgesia has several advantages over the traditional epidural technique, including faster onset, greater maternal satisfaction, and decreased need for physician boluses. Proponents of the epidural technique criticize the combined spinal-epidural technique, arguing that the epidural catheter remains untested and thus may not be reliable if needed for surgical intervention. We compared failure rates and time of failure between techniques in our tertiary-care academic practice. Data regarding failed catheters were collected from October 2012 to September 2014 as part of our Quality Assurance program. Failed catheters were defined as any catheter replaced after it was considered to be properly placed and then determined to be intravascular, one sided or resulting in poor maternal analgesia or anesthesia. A total of 5487 analgesics were performed (3980 combined spinal-epidural; 1507 epidural). Eighty-five combined spinal-epidural catheters (2.1%) and 59 epidural catheters (3.9%) were replaced during labor (Plabor and that the time to detection of a failed catheter was significantly longer in the combined spinal-epidural group. Our findings validate the combined spinal-epidural technique as reliable for labor analgesia and tend to refute the theory of the untested catheter. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Estudio observacional de la analgesia epidural para trabajo de parto: Complicaciones de la técnica en 5.895 embarazadas Observational study of epidural analgesia used in labour: Complications of this technique in 5,895 pregnant women

    OpenAIRE

    Calvo, M.; Gilsanz, F; Palacio, F.; I. Fornet; N. Arce

    2005-01-01

    Objetivos: a) Conocer la incidencia de las complicaciones relacionadas con la técnica de analgesia regional durante la realización de la técnica, durante la dilatación y en el postparto; y b) conocer si las complicaciones del postparto relacionadas con la técnica analgésica son más frecuentes cuando se realiza la técnica combinada epidural-subaracnoidea (CES) en comparación con la analgesia epidural. Material y método: Hemos realizado un estudio observacional descriptivo y analítico. Como suj...

  13. Epidural and opioid analgesia following the Nuss procedure

    Science.gov (United States)

    Walaszczyk, Malgorzata; Knapik, Piotr; Misiolek, Hanna; Korlacki, Wojciech

    2011-01-01

    Summary Background Parents have the right to decide on behalf of their children and deny consent to regional anaesthesia. The investigators decided to investigate quality of postoperative analgesia in adolescents undergoing epidural and opioid analgesia following the Nuss procedure. Material/Methods The study subjects were 61 adolescents aged 11–18 years who underwent pectus excavatum repair with the Nuss procedure. Patients were divided into epidural (n=41) and opioid (n=20) groups, depending on their parents’ consent to epidural catheter insertion. Intraoperatively, 0.5% epidural ropivacaine with fentanyl or intermittent intravenous injections of fentanyl were used. Postoperative analgesia was achieved with either epidural infusion of 0.1% ropivacaine with fentanyl, or subcutaneous morphine via an intraoperatively inserted “butterfly” cannula. Additionally, both groups received metamizol and paracetamol. Primary outcome variables were postoperative pain scores (Numeric Rating Scale and Prince Henry Hospital Pain Score). Secondary outcome variables included hemodynamic parameters, additional analgesia and side effects. Results Heart rate and blood pressure values in the postoperative period were significantly higher in the opioid group. Pain scores requiring intervention were noted almost exclusively in the opioid group. Conclusions Denial of parental consent to epidural analgesia following the Nuss procedure results in significantly worse control of postoperative pain. Our data may be useful when discussing with parents the available anaesthetic techniques for exceptionally painful procedures. PMID:22037752

  14. Hands-and-knees positioning during labor with epidural analgesia.

    Science.gov (United States)

    Stremler, Robyn; Halpern, Stephen; Weston, Julie; Yee, Jennifer; Hodnett, Ellen

    2009-01-01

    Hands-and-knees position has shown promise as an intervention to improve labor and birth outcomes, but no reports exist that examine its use with women laboring with epidural analgesia. Concerns of safety, effects on analgesia, and acceptability of use may limit use of active positioning during labor with regional analgesia. This article presents a case study series of 13 women who used hands-and-knees position in the first stage of labor.

  15. Racial differences in the use of epidural analgesia for labor.

    Science.gov (United States)

    Glance, Laurent G; Wissler, Richard; Glantz, Christopher; Osler, Turner M; Mukamel, Dana B; Dick, Andrew W

    2007-01-01

    There is strong evidence that pain is undertreated in black and Hispanic patients. The association between race and ethnicity and the use of epidural analgesia for labor is not well described. Using the New York State Perinatal Database, the authors examined whether race and ethnicity were associated with the likelihood of receiving epidural analgesia for labor after adjusting for clinical characteristics, demographics, insurance coverage, and provider effect. This retrospective cohort study was based on 81,883 women admitted for childbirth between 1998 and 2003. Overall, 38.3% of the patients received epidural analgesia for labor. After adjusting for clinical risk factors, socioeconomic status, and provider fixed effects, Hispanic and black patients were less likely than non-Hispanic white patients to receive epidural analgesia: The adjusted odds ratio was 0.85 (95% CI, 0.78-0.93) for white/Hispanic and 0.78 (0.74-0.83) for blacks compared with non-Hispanic whites. Compared with patients with private insurance, patients without insurance were least likely to receive epidural analgesia (adjusted odds ratio, 0.76; 95% CI, 0.64-0.89). Black patients with private insurance had similar rates of epidural use to white/non-Hispanic patients without insurance coverage: The adjusted odds ratio was 0.66 (95% CI, 0.53-0.82) for white/non-Hispanic patients without insurance versus 0.69 (0.57-0.85) for black patients with private insurance. Black and Hispanic women in labor are less likely than non-Hispanic white women to receive epidural analgesia. These differences remain after accounting for differences in insurance coverage, provider practice, and clinical characteristics.

  16. LABOUR ANALGESIA: EPIDURAL DEXMEDITOMIDINE WITH EITHER BUPIVACAINE OR ROPIVACAINE

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    Varaprasad

    2015-07-01

    Full Text Available BACKGROUND: Pain relief in labour is associated with myths and controversies. Providing effective and safe analgesia has remained a challenge. AIM: The purpose of the study was to compare the effect of analgesia with epidural bupivacain or ropivacain along with dexme ditomidine. METHODS AND MATERIAL: Sixty parturients of ASA grade I and II were randomly selected for the study. Each group consisted of thirty patients. The analgesia, motor loss and level of sedation were studied. RESULTS: There was no significant differ ence between the two groups in maternal satisfaction, analgesia and neonatal outcome .

  17. Efecto de la hidratación endovenosa con hidroxietil almidón 6% 130/0.4 (voluven®) versus ringer lactato previa a la analgesia epidural en la incidencia de hipotensión durante el trabajo de parto

    OpenAIRE

    Francés González, Sonia

    2015-01-01

    La fluidoterapia endovenosa en las gestantes durante trabajo de parto es fundamental para la prevención de la hipotensión materna tras la analgesia epidural y así mantener el bienestar materno-fetal. El tipo de fluidoterapia administrada, coloides o cristaloides, puede influir en la incidencia de dicha hipotensión. Presentamos los resultados de un estudio prospectivo observacional de 188 gestantes en trabajo de parto. El objetivo principal del estudio fue comparar la incidencia de hipotensión...

  18. Epidural analgesia during labour - maternal understanding and experience - informed consent.

    Science.gov (United States)

    Mahomed, K; Chin, D; Drew, A

    2015-01-01

    Women obtain information on epidural analgesia from various sources. For epidural for pain relief in labour this is provided by the anaesthetist as part of the consenting process. There is much discussion about the inadequacy of this consenting process; we report on women's knowledge, experience and recall of this process at a regional hospital with a 24-h epidural service. Fifty-four women were interviewed within 72 h of a vaginal birth. 91% of the women had acquired information from friends, relatives and antenatal classes. Lack of recall of benefits of epidural analgesia accounted for 26 (38%) and 25 (26%) of the responses, respectively. Similarly in terms of amount of pain relief they could expect, 13 (21%) could not remember and 13 (21%) thought that it may not work. We suggest use of varying methods of disseminating information and wider utilisation of anaesthetists in the antenatal educational programmes.

  19. Epidural blood flow and regression of sensory analgesia during continuous postoperative epidural infusion of bupivacaine

    DEFF Research Database (Denmark)

    Mogensen, T; Højgaard, L; Scott, N B;

    1988-01-01

    Epidural blood flow was measured in seven patients undergoing elective abdominal surgery during combined lumbar epidural and general anesthesia. After an initial dose of 20 ml plain bupivacaine 0.5%, a continuous epidural infusion of bupivacaine 0.5% (8 ml/hr) was given for 16 hours for postopera......Epidural blood flow was measured in seven patients undergoing elective abdominal surgery during combined lumbar epidural and general anesthesia. After an initial dose of 20 ml plain bupivacaine 0.5%, a continuous epidural infusion of bupivacaine 0.5% (8 ml/hr) was given for 16 hours...... surgery, and 8, 12, and 16 hours later during the continuous infusion. Initial blood flow was 6.0 +/- 0.7 ml/min per 100 g tissue (mean +/- SEM). After epidural bupivacaine, blood flow increased in all seven patients to 7.4 +/- 0.7 ml (P less than 0.02). Initial level of sensory analgesia was T4.5 +/- 0...... than 0.03) in the other five patients as the level of sensory analgesia regressed postoperatively. These data suggest that changes in epidural blood flow during continuous epidural infusion of bupivacaine, and thus changes in rates of vascular absorption of bupivacaine from the epidural space, may...

  20. Hyperventilation-induced tetany associated with epidural analgesia for labor.

    Science.gov (United States)

    Ray, N; Camann, W

    2005-01-01

    We report a case of painful carpo-pedal spasm associated with the initiation of epidural analgesia for labor. The patient, an otherwise healthy primigravida in early labor at term, was experiencing severe hyperventilation as a result of inappropriate use of the Lamaze breathing technique. Bilateral carpo-pedal spasm occurred, and produced severe pain. Resolution of symptoms coincided with onset of effective epidural labor pain relief. A diagnostic challenge was presented to the anesthesiologist, as the symptoms could have been consistent with subdural block, local anesthetic toxicity, high sensory level of analgesia or eclamptic neuro-excitation activity.

  1. CLINICAL EFFECTS OF ROPIVACAINE MESYLATE IN EPIDURAL ANESTHESIA AND ANALGESIA

    Institute of Scientific and Technical Information of China (English)

    Jian-qing Xu; Bo Zhu; Tie-hu Ye

    2005-01-01

    @@ SINCE the report that ropivacaine hydrochloride, a new amide local anesthetic, is of lower cardiac toxicity both in animals and humans,1 several studies have shown it to be a clinically effective local anesthetic widely used for both epidural anesthesia2-4 and analgesia5-7. Ropivacaine mesylate made in China is structurally from ropivacaine hydrochloride by substituting a mesylate group for hydrochloride group.8 This study was designed to clinically provide a double-blind comparison of ropivacaine mesylate with ropivacaine hydrochloride in epidural anesthesia and analgesia.

  2. Remifentanil patient controlled analgesia versus epidural analgesia in labour. A multicentre randomized controlled trial

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    Freeman Liv M

    2012-07-01

    Full Text Available Abstract Background Pain relief during labour is a topic of major interest in the Netherlands. Epidural analgesia is considered to be the most effective method of pain relief and recommended as first choice. However its uptake by pregnant women is limited compared to other western countries, partly as a result of non-availability due to logistic problems. Remifentanil, a synthetic opioid, is very suitable for patient controlled analgesia. Recent studies show that epidural analgesia is superior to remifentanil patient controlled analgesia in terms of pain intensity score; however there was no difference in satisfaction with pain relief between both treatments. Methods/design The proposed study is a multicentre randomized controlled study that assesses the cost-effectiveness of remifentanil patient controlled analgesia compared to epidural analgesia. We hypothesize that remifentanil patient controlled analgesia is as effective in improving pain appreciation scores as epidural analgesia, with lower costs and easier achievement of 24 hours availability of pain relief for women in labour and efficient pain relief for those with a contraindication for epidural analgesia. Eligible women will be informed about the study and randomized before active labour has started. Women will be randomly allocated to a strategy based on epidural analgesia or on remifentanil patient controlled analgesia when they request pain relief during labour. Primary outcome is the pain appreciation score, i.e. satisfaction with pain relief. Secondary outcome parameters are costs, patient satisfaction, pain scores (pain-intensity, mode of delivery and maternal and neonatal side effects. The economic analysis will be performed from a short-term healthcare perspective. For both strategies the cost of perinatal care for mother and child, starting at the onset of labour and ending ten days after delivery, will be registered and compared. Discussion This study, considering cost

  3. Analgesia epidural obstétrica: fallos y complicaciones neurológicas de la técnica Obstetric epidural analgesia: failures and neurological complications of the technique

    OpenAIRE

    M. I. Segado-Jiménez; J. Arias-Delgado; F. Domínguez-Hervella; M. L. Casas-García; A. López-Pérez; C. Izquierdo-Gutiérrez

    2011-01-01

    Objetivos: Estudiar la incidencia de fallos y complicaciones neurológicas de la analgesia epidural en obstetricia, así como hacer un seguimiento y análisis de las mismas. Pacientes y método: Estudio observacional prospectivo de gestantes que recibieron analgesia epidural para el trabajo de parto en un hospital terciario durante 2009 y 2010. Se registraron los datos demográficos maternoinfantiles, del trabajo de parto y el tipo de parto así como las complicaciones que se produjeron tanto duran...

  4. Epidural analgesia associated with better survival in colon cancer.

    Science.gov (United States)

    Vogelaar, F J; Abegg, R; van der Linden, J C; Cornelisse, H G J M; van Dorsten, F R C; Lemmens, V E; Bosscha, K

    2015-08-01

    Surgery remains the mainstay of treatment for potentially curable colon cancer. Otherwise, the surgical stress response might increase the likelihood of cancer dissemination during and after cancer surgery. There is growing evidence that the type of anaesthesia during cancer surgery plays a role in the metastatic process. Therefore, we assessed if the method of anaesthesia is associated with long-term survival after colon cancer surgery. A retrospective single-centre study was conducted including 588 patients who underwent colorectal cancer surgery, TNM stage I-IV, in the Jeroen Bosch Hospital between 1995 and 2003. The Cox proportional hazard model was used for statistical analysis. Adjustments were made for age, sex, comorbidity, TNM stage, chemotherapy, emergency surgery status and year of incidence. Of the 588 primary colon cancer patients with a median age of 70 years, 399 (68 %) patients underwent colon surgery with epidural anaesthesia, whilst 189 (32 %) patients were operated without epidural anaesthesia. Five-year survival for patients not receiving epidural analgesia was 42 % versus 51 % for patients receiving epidural analgesia (p = 0.03). This effect remained after adjustment for relevant patient, tumour, and treatment characteristics (hazard ratio (HR) 1.30 (95 % confidence interval (CI) 1.05-1.59), p = 0.01). Subgroup analysis in patients of 80 years and older (n = 100) showed also a better overall survival after receiving epidural analgesia (HR 1.74 (95 % CI 1.11-2.72), p = 0.01). Epidural analgesia during colon cancer surgery was associated with a better overall survival. Prospective trials evaluating the effects of locoregional analgesia on colon cancer recurrence are warranted.

  5. Optimal Dose of Epidural Dexmedetomidine Added to Ropivacaine for Epidural Labor Analgesia: A Pilot Study

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    Zhang Wangping

    2017-01-01

    Full Text Available Background. Dexmedetomidine combined with local anesthetics can decrease the concentration of epidural ropivacaine. However, the optimal dose of epidural dexmedetomidine combined with ropivacaine for labor analgesia is still uncertain. This study investigated the effect of adding different dose of epidural dexmedetomidine to ropivacaine during epidural labor analgesia. Methods. One hundred women were randomly assigned to one of the four groups (Groups A, B, C, and D received 0.25, 0.5, 0.75, and 1 μg/ml of dexmedetomidine plus 0.1% ropivacaine, resp.. The onset of epidural anesthesia and stages of labor were studied, and pain was assessed using a visual analogue scale (VAS. Hemodynamic parameters and fetal heart rate were monitored. Apgar scores and umbilical artery pH were recorded. The side effects, if any, were recorded also. Results. The addition of 0.25, 0.5, and 0.75 μg/ml of dexmedetomidine to 0.1% ropivacaine provided safe and effective analgesia, but 1 μg/ml of dexmedetomidine resulted in increasing incidence of motor block. The hemodynamic parameters were similar between groups (P>0.05. Side effects in Group D were significantly higher than those in the other three groups (P<0.05. Conclusions. When dexmedetomidine is combined with 0.1% ropivacaine, the optimal concentration of dexmedetomidine is 0.5 μg/ml for epidural labor analgesia (this trial is registered with ChiCTR-OPC-16008548.

  6. Comparison of continuous epidural infusion and programmed intermittent epidural bolus in labor analgesia

    Directory of Open Access Journals (Sweden)

    Lin Y

    2016-07-01

    Full Text Available Yunan Lin, Qiang Li, Jinlu Liu, Ruimin Yang, Jingchen Liu Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China Background: This study aims to investigate differences between continuous epidural infusion (CEI and programmed intermittent epidural bolus (IEB analgesia for the Chinese parturients undergoing spontaneous delivery and to approach their safety to parturients and neonates.Methods: Two hundred healthy American Society of Anesthesiologists class I or II, term (≥37 weeks’ gestation, nulliparous women who requested analgesia for labor were recruited. Epidural analgesia was initiated with a solution of 0.15% ropivacaine 10 mL and maintained with 0.1% ropivacaine mixed with sufentanil 0.3 µg/mL by CEI at a rate of 5 mL/h combined with a patient-controlled epidural analgesia (PCEA bolus of 5 mL of ropivacaine sufentanil mixture or IEB of 5 mL of ropivacaine sufentanil mixture combined with a PCEA bolus of 5 mL of ropivacaine sufentanil mixture. The lockout interval was 20 minutes in each arm between the CEI and the IEB group. After 20 minutes of first dosage, visual analog scale (VAS score was obtained every 60 minutes. The maternal and fetal outcome and total consumption of analgesic solution were compared.Results: There was no difference in demographic characteristics, duration of first and second stages, delivery methods, sensory block, fetal Apgar scores, and the maternal outcomes between the CEI and IEB groups. There was a significant difference in VAS scores and epidural ropivacaine total consumption between the two groups (IEB vs CEI: 51.27±9.61 vs 70.44±12.78 mg, P<0.01. Conclusion: The use of programmed IEB mixed with PCEA improved labor analgesia compared to CEI mixed with PCEA, which could act as maintenance mode for epidural labor analgesia. Keywords: intermittent epidural bolus, continuous epidural infusion, labor analgesia, patient

  7. Estudio observacional de la analgesia epidural para trabajo de parto: Complicaciones de la técnica en 5.895 embarazadas Observational study of epidural analgesia used in labour: Complications of this technique in 5,895 pregnant women

    Directory of Open Access Journals (Sweden)

    M. Calvo

    2005-04-01

    Full Text Available Objetivos: a Conocer la incidencia de las complicaciones relacionadas con la técnica de analgesia regional durante la realización de la técnica, durante la dilatación y en el postparto; y b conocer si las complicaciones del postparto relacionadas con la técnica analgésica son más frecuentes cuando se realiza la técnica combinada epidural-subaracnoidea (CES en comparación con la analgesia epidural. Material y método: Hemos realizado un estudio observacional descriptivo y analítico. Como sujetos del estudio hemos incluido a todas las mujeres que solicitaron la administración de analgesia regional a la Unidad de Analgesia Epidural de nuestro hospital (5.895 embarazadas y cumplían los criterios de inclusión, en un periodo de tiempo que empieza en el 1 de enero del año 2002 y termina el 1 de enero del año 2003. Las técnicas empleadas para el control del dolor del trabajo del parto fueron la analgesia epidural y la técnica combinada epidural-subaracnoidea. Resultados: La complicación que más frecuentemente apareció durante la realización de la técnica fueron las parestesias (43,5% seguido de la punción hemática (5,9%. La punción no intencionada de la duramadre ha ocurrido en el 0,6%. Las complicaciones que más frecuentemente aparecieron durante el periodo de dilatación fue el prurito (11,4% y la analgesia lateralizada (9%. La complicación más frecuente del periodo postparto fue el dolor de espalda (9,8% y la cefalea (2%. Las complicaciones en general han sido significativamente más frecuentes en las embarazadas a las que se les aplicó la técnica CES, en comparación con la analgesia epidural convencional. Conclusiones: Las complicaciones que pueden aparecer debido a este modo de analgesia van desde unas poco frecuentes y potencialmente peligrosas si pasan desapercibidas (como la inyección intravascular de anestésicos locales o el bloqueo espinal total a otras más frecuentes como las parestesias, con una repercusi

  8. Paraplegia following epidural analgesia: A potentially avoidable cause?

    Directory of Open Access Journals (Sweden)

    Jeson R Doctor

    2014-01-01

    Full Text Available Neurological deficit is an uncommon but catastrophic complication of epidural anesthesia. Epidural hematomas and abscesses are the most common causes of such neurological deficit. We report the case of a patient with renal cell carcinoma with lumbar vertebral metastasis who developed paraplegia after receiving thoracic epidural anesthesia for a nephrectomy. Subsequently, on histo-pathological examination of the laminectomy specimen, the patient was found to have previously undiagnosed thoracic vertebral metastases which led to a thoracic epidural hematoma. In addition, delayed reporting of symptoms of neurological deficit by the patient may have impacted his outcome. Careful pre-operative investigation, consideration to using alternative modalities of analgesia, detailed patient counseling and stringent monitoring of patients receiving central neuraxial blockade is essential to prevent such complications.

  9. Labor analgesia: An update on the effect of epidural analgesia on labor outcome

    Directory of Open Access Journals (Sweden)

    Samina Ismail

    2013-01-01

    Full Text Available Following the introduction of epidural for labor analgesia, debate has centered on the issue of its effect on outcome of labor; in terms of length of labor and increase in the rate of instrumental vaginal delivery and cesarean section (CS. There is no ideal study on the effect of epidural analgesia (EA on the outcome of labor due to logistic problems in randomization, blinding and getting a control group; as a result these queries are partly answered. Despite these problems, it has been established that labor epidural has minimal effect on progress of established labor and maternal request should be a sufficient indication to start an epidural. Although instrumental vaginal delivery is probably increased with epidural but obstetrician practice, pain free patient and teaching opportunity are likely factors increasing the incidence. Maternal-fetal factors and obstetric management and not the use of EA are the most important determinants of the CS rate. The purpose of this review is to summarize data from controlled trials addressing the question of whether neuraxial labor analgesia causes an increased risk of CS or rate of instrumental delivery. In addition, the review discusses whether the timing of initiation of analgesia infl uences the mode of delivery.

  10. Labour epidural analgesia in Poland in 2009 - a survey.

    Science.gov (United States)

    Furmanik, Jacek

    2013-01-01

    Labour analgesia in most developed countries is funded by the state, available to every woman in labour, and plays an important role in the everyday activities of most anaesthetists. This paper presents the second part of an Obstetric Anaesthesia Survey which was conducted in 2009. The first part of the Survey, relating to anaesthesia for caesarean sections, was published in 2010. The author sent out 432 questionnaires containing questions about hospital size and location, staffing levels and numbers of deliveries per year. There were also questions regarding regional and other pain relief methods used in labour, ways of administration, drugs used and monitoring of patients. The response rate was 24%. Around 45% of responding hospitals had only 1-3 deliveries per year, which makes it difficult to provide separate obstetric anaesthetic cover. Only ten hospitals (11%) employed an anaesthetist for the labour ward. Epidural analgesia was used in 55% of hospitals but only 20% provided the service for 24 hours per day and free of charge. Entonox was used very occasionally, but the most common means of pain relief was pethidine injection. There were marked differences in the medication used for labour epidurals, with 18% of units using high concentrations of local anaesthetics which could result in motor block. Despite a lack of regulations in Polish law and a lack of proper training in 50% of units, midwives were looking after the patients with established labour epidural which could create medico-legal consequences. There was also a marked variation in the parameters monitored during labour analgesia. Epidural labour analgesia was offered for 24 hours per day and free of charge in only 20% of hospitals. Without public pressure it will be difficult to get more funding from the National Health Fund (NFZ) to enable other hospitals, especially those with small obstetric units, to introduce regional labour analgesia. Although the 2009 guidelines addressed most of the issues

  11. Remifentanil patient controlled analgesia versus epidural analgesia in labour. A multicentre randomized controlled trial

    NARCIS (Netherlands)

    Freeman, Liv M.; Bloemenkamp, Kitty W. M.; Franssen, Maureen T. M.; Papatsonis, Dimitri N. M.; Hajenius, Petra J.; van Huizen, Marloes E.; Bremer, Henk A.; van den Akker, Eline S. A.; Woiski, Mallory D.; Porath, Martina M.; van Beek, Erik; Schuitemaker, Nico; van der Salm, Paulien C. M.; Fong, Bianca F.; Radder, Celine; Bax, Caroline J.; Sikkema, Marko; van den Akker-van Marle, M. Elske; van Lith, Jan M. M.; Lopriore, Enrico; Uildriks, Renske J.; Struys, Michel M. R. F.; Mol, Ben Willem J.; Dahan, Albert; Middeldorp, Johanna M.

    2012-01-01

    Background: Pain relief during labour is a topic of major interest in the Netherlands. Epidural analgesia is considered to be the most effective method of pain relief and recommended as first choice. However its uptake by pregnant women is limited compared to other western countries, partly as a res

  12. [Epidural analgesia in obstetrics: is there an effect on labor and delivery?].

    Science.gov (United States)

    Segado Jiménez, M I; Arias Delgado, J; Domínguez Hervella, F; Casas García, M L; López Pérez, A; Izquierdo Gutiérrez, C

    2011-01-01

    Epidural analgesia is routinely used in obstetrics but has been blamed for possible effects on labor that lead to greater use of instruments or conversion to cesarean delivery. We aimed to assess this possibility in a cohort of obstetric patients receiving or not receiving epidural analgesia. Prospectively enrolled full-term obstetric patients were distributed in 2 groups according to whether they received epidural analgesia or not. We compared maternal and fetal characteristics, obstetric variables, and type of delivery between groups to record the likely causes of difficult labor and delivery and detect a possible influence of epidural analgesia. Of a total of 602 patients, 462 received epidural analgesia and 140 did not. Epidural analgesia was related to a higher rate of use of instruments but not cesareans (P labor (6.4 [4.2] hours in the epidural group vs 4.7 [3.5] hours in the no-epidural group, P initiation of epidural analgesia after the fetus has reached Hodge's first plane decreased risk 2.7-fold and 3.03-fold, respectively. Although epidural analgesia has traditionally been associated with a higher incidence of difficult labor and delivery, this association was not unequivocally evident in this cohort of patients. The apparent increase seems to be attributable to such obstetric factors as longer duration of stages of labor, higher body mass index, and first delivery.

  13. Epidural analgesia practices for labour: results of a 2005 national survey in Ireland.

    LENUS (Irish Health Repository)

    Fanning, Rebecca A

    2012-02-01

    BACKGROUND AND OBJECTIVE: The last 25 years have seen changes in the management of epidural analgesia for labour, including the advent of low-dose epidural analgesia, the development of new local anaesthetic agents, various regimes for maintaining epidural analgesia and the practice of combined spinal-epidural analgesia. We conducted a survey of Irish obstetric anaesthetists to obtain information regarding the conduct and management of obstetric epidural analgesia in Ireland in 2005. The specific objective of this survey was to discover whether new developments in obstetric anaesthesia have been incorporated into clinical practice. METHODS: A postal survey was sent to all anaesthetists with a clinical commitment for obstetric anaesthesia in the sites approved for training by the College of Anaesthetists, Ireland. RESULTS: Fifty-three per cent of anaesthetists surveyed responded. The majority of anaesthetists (98%) use low-dose epidural analgesia for the maintenance of analgesia. Only 11% use it for test-dosing and 32% for the induction of analgesia. The combined spinal-epidural analgesia method is used by 49%, but two-thirds of those who use it perform fewer than five per month. Patient-controlled epidural analgesia was in use at only one site. CONCLUSION: It appears that Irish obstetric anaesthetists have adopted the low-dose epidural analgesia trend for the maintenance of labour analgesia. This practice is not as widespread, however, for test dosing, the induction of analgesia dose or in the administration of intermittent epidural boluses to maintain analgesia when higher concentrations are used. Since its introduction in 2000, levobupivacaine has become the most popular local anaesthetic agent.

  14. Update on epidural analgesia during labor and delivery.

    Science.gov (United States)

    Lurie, S; Priscu, V

    1993-05-01

    Properly administered epidural analgesia provides adequate pain relief during labor and delivery, shortens the first stage of labor, avoids adverse effects of narcotics, hypnotics, or inhalation drugs and it could be used as anesthesia in case a cesarean section is required. Epidural analgesia should be provided to all patients who need and ask for it with an exception of contraindications such as coagulation disorders, suspected infection or gross anatomic abnormality. The technique must be carried out with care if serious life-threatening complications, such as intravenous or intrathecal injection of local anesthetic, are to be avoided. The aim of many recent investigations has been to reduce the total dose of local anesthetic used. Supplementation of an opioid (mainly fentanyl) and introduction of the patient controlled epidural pump may not only serve this goal, but also reduce the demands on the time of obstetric anesthetists. We conclude that properly and skillfully administered epidural is the best form of pain relief during labor and delivery and we hope that more mothers could enjoy its benefits.

  15. A randomized, controlled trial comparing local infiltration analgesia with epidural infusion for total knee arthroplasty

    DEFF Research Database (Denmark)

    Andersen, Karen Vestergaard; Bak, Marie; Christensen, Birgitte Viebæk;

    2010-01-01

    There have been few studies describing wound infiltration with additional intraarticular administration of multimodal analgesia for total knee arthroplasty (TKA). In this study, we assessed the efficacy of wound infiltration combined with intraarticular regional analgesia with epidural infusion...

  16. Prospective, randomized, controlled trial of thoracic epidural or patient-controlled opiate analgesia on perioperative quality of life.

    LENUS (Irish Health Repository)

    Ali, M

    2010-03-01

    Perioperative epidural analgesia provides continuous pain control and may have advantages over parenteral opiate administration. This study assessed the impact of epidural analgesia on quality of life (QOL) of patients undergoing major surgery.

  17. [Comparison of ropivacaine and bupivacaine for epidural analgesia during labor].

    Science.gov (United States)

    Sánchez-Conde, P; Nicolás, J; Rodríguez, J; García-Castaño, M; del Barrio, E; Muriel, C

    2001-05-01

    To compare the analgesic efficacy and level of motor block using two local anesthetics, ropivacaine and bupivacaine, during labor. Sixty nulliparous women were enrolled during labor after full-term pregnancies. They were randomly assigned to receive epidural analgesia with ropivacaine (group R) or bupivacaine (group B). Group R patients received 10 ml of 0.18% ropivacaine with 5 microgram/ml of fentanyl followed by continuous epidural infusion of 0.1% ropivacaine with 2 microgram/ml of fentanyl at a rate of 10 ml/h. Group B patients received 10 ml of 0.15% bupivacaine with 5 microgram/ml of fentanyl followed by continuous epidural perfusion of 0.0625% bupivacaine with 2 microgram/ml of fentanyl at the same rate. Pain intensity was assessed on a visual analog scale, motor blockade on a Bromage scale, and level of sensory block at different moments. We also recorded total doses of local anesthetic employed during continuous epidural infusion, manner of final delivery, Apgar score, degree of maternal satisfaction and side effects. The demographic and delivery characteristics were similar in both groups. We found no statistically significant differences between the two groups for level of motor blockade, which was nil for 29 patients (96.66%) in group R and 28 patients (93.33%) in group B. No differences in degree of pain or level of sensory block (T8-T10 in both groups) were observed. The total doses of local anesthetic used were similar at 23.7 +/- 11.6 mg in group R and 16.5 +/- 7.3 mg in group B (non-significant difference). Nor did we find differences in manner of delivery, neonatal Apgar scores, degree of maternal satisfaction or side effects. Ropivacaine and bupivacaine are equally effective for epidural analgesia during labor at the doses used and they do not cause a relevant level of motor blockade.

  18. Epidural blood flow and regression of sensory analgesia during continuous postoperative epidural infusion of bupivacaine

    DEFF Research Database (Denmark)

    Mogensen, T; Højgaard, L; Scott, N B;

    1988-01-01

    Epidural blood flow was measured in seven patients undergoing elective abdominal surgery during combined lumbar epidural and general anesthesia. After an initial dose of 20 ml plain bupivacaine 0.5%, a continuous epidural infusion of bupivacaine 0.5% (8 ml/hr) was given for 16 hours...... for postoperative pain relief. The epidural blood flow was measured by a local 133Xe clearance technique in which 15-35 MBq 133Xe diluted in 1 ml saline was injected through the epidural catheter on the day before surgery (no bupivacaine), 30 minutes after the initial dose of bupivacaine on the morning before...... surgery, and 8, 12, and 16 hours later during the continuous infusion. Initial blood flow was 6.0 +/- 0.7 ml/min per 100 g tissue (mean +/- SEM). After epidural bupivacaine, blood flow increased in all seven patients to 7.4 +/- 0.7 ml (P less than 0.02). Initial level of sensory analgesia was T4.5 +/- 0...

  19. Mode of delivery after epidural analgesia in a cohort of low-risk nulliparas

    DEFF Research Database (Denmark)

    Eriksen, Lena Mariann; Nøhr, Ellen Aagaard; Kjaergaard, Hanne

    2011-01-01

    Although epidural analgesia is widespread and very effective for alleviating labor pain, its use is still controversial, as the literature is inconsistent about the risk of adverse birth outcome after administration of epidural analgesia. The aim of this study was to explore associations between...

  20. Epidural analgesia and anticoagulant therapy. Experience with one thousand cases of continuous epidurals.

    Science.gov (United States)

    Odoom, J A; Sih, I L

    1983-03-01

    One thousand lumbar epidural blocks in 950 patients undergoing vascular surgery are reported. All patients were receiving oral anticoagulants pre-operatively. Mean thrombotest (TT) was 19.3% (normal range 70-130%). During surgery intravascular heparin was administered. At the end of surgery, the kaolin cephalin clotting time (KCCT) was 68 (+/- 0.8) seconds (normal range 35-60 seconds), and partial thromboplastin time (PTT) was 536 (77.9%, normal control of 100%). Despite the anticoagulant therapy, no side effects were observed in any patient which could be related to haemorrhage or haematoma formation in the epidural space. It is concluded that, provided adequate precautions are taken, epidural analgesia can be safely used in patients receiving anticoagulant therapy.

  1. A COMPARATIVE STUDY OF EPIDURAL BUPIVACAINE WITH CLONIDINE AND EPIDURAL BUPIVACAINE FOR POST OPERATIVE ANALGESIA

    Directory of Open Access Journals (Sweden)

    Durga Prasad

    2015-10-01

    Full Text Available BACKGROUND: Clonidine, an α 2 - adrenoreceptor agonist, administered epidurally, is gaining popularity for its analgesic, sympatholytic, hemodynamic stabilizing and sedative properties without significant side effects. METHODS: This present study “ A Comparative Study o f Epidural Bupivac aine w ith Clonidine a nd Epidural Bupivacaine f or Post - o perative Analgesia ” was conducted in 70 cases of ASA grade I and II, between the age groups of 30 - 75yrs undergoing abdominal, gynecological and orthopedic surgeries under epidural anaesthesia. At the e nd of surgery, patients were shifted to recovery room. When patients complained of pain with VAS > 4/10, they were allocated to receive either of B: Plain Bupivacaine 0.125% 10ml (n = 35. B+C: Clonidine 150 mcg (1ml + 0.125% Bupivacaine 9ml (n = 35. The following parameters were monitored: A. Onset of analgesia . B. Duration of analgesia . C. VAS and Quality of analgesia . D. ardio - respiratory effects: Pulse rate, blood pressure, respiratory rate. E. Side effects like: nausea, vomiting, pruritus, hypotensio n, sedation and respiratory depression were studied. ONSET OF ANALGESIA: The time of onset of analgesia in group (B+C was significantly less (12.7 ± 0.87 (S.D min when compared to g roup (B (16 ± 3.34 (S.D min. DURATION OF ANALGESIA: The duration of a nalgesia in group (B+C (225.2 ± 45.74 (SD min was significantly more when compared to group (B (119 ± 29.29 (SD min. VISUAL ANALOGUE SCORE: In comparison of group B and group B+C, highly significant difference in VAS was seen from 15min till 3.5hrs in between the groups. The quality of analgesia in Group B+C was VAS 3 - 4 (good to excellent pain relief, as compared to Group B, where VAS was 2 - 3 (fair to good pain relief. SEDATION: In Group B+C from 30min till 2hrs, 100% of patients were asleep (sedat ion score 3. Even in patients with sedation score 3, patients were calm, quiet and asleep but when questions were asked, they answered with

  2. [High thoracic epidural analgesia in the postoperative period after correction of congenital heart defects in children].

    Science.gov (United States)

    Slin'ko, S K

    1999-01-01

    The effects and side effects of thoracic epidural analgesia on the respiratory response, awakening time, and cooperation with nurses were studied. Forty children received epidural analgesia after open-heart surgery. Lidocaine was injected in a dose of 1.5-2 mg/kg every 1.5-2 h. Controls (16 pts) received intravenous fentanyl + diazepam analgesia. Respiratory response and awakening were significantly earlier (p < 0.001) in the epidural group. Cooperation with nurses was much better in this group, too. No side effects were observed in the epidural group. Therefore, thoracic epidural analgesia is a safe and effective method of postoperative analgesia for children subjected to open-heart surgery.

  3. Epidural analgesia during labor and delivery: effects on the initiation and continuation of effective breastfeeding.

    Science.gov (United States)

    Chang, Zorina Marzan; Heaman, Maureen I

    2005-08-01

    This prospective cohort study examined the association between epidural analgesia during labor and delivery, infant neurobehavioral status, and the initiation and continuation of effective breastfeeding. Healthy, term infants delivered vaginally by mothers who received epidural analgesia (n = 52) or no analgesia (n = 63) during labor and delivery were assessed at 8 to 12 hours postpartum, followed by a telephone interview with the mothers at 4 weeks postpartum. There was no significant difference between the epidural analgesia and no-analgesia groups in breastfeeding effectiveness or infant neurobehavioral status at 8 to 12 hours or in the proportion of mothers continuing to breastfeed at 4 weeks. Therefore, epidural analgesia did not appear to inhibit effective breastfeeding. There was a positive correlation between infant neurobehavioral status and breastfeeding effectiveness (Spearman rho = 0.48, P = .01), suggesting that neurobehavioral assessment may prove beneficial in identifying infants at greater risk for breastfeeding difficulties.

  4. Analgesia epidural obstétrica: fallos y complicaciones neurológicas de la técnica Obstetric epidural analgesia: failures and neurological complications of the technique

    Directory of Open Access Journals (Sweden)

    M. I. Segado-Jiménez

    2011-10-01

    Full Text Available Objetivos: Estudiar la incidencia de fallos y complicaciones neurológicas de la analgesia epidural en obstetricia, así como hacer un seguimiento y análisis de las mismas. Pacientes y método: Estudio observacional prospectivo de gestantes que recibieron analgesia epidural para el trabajo de parto en un hospital terciario durante 2009 y 2010. Se registraron los datos demográficos maternoinfantiles, del trabajo de parto y el tipo de parto así como las complicaciones que se produjeron tanto durante la realización de la técnica como durante el peri- y postparto. Se siguieron a todas las pacientes hasta su alta hospitalaria identificándose y tratándose las posibles complicaciones hasta su resolución. Resultados: Se incluyeron 438 gestantes. Se dividieron las complicaciones en 2 etapas: peripartum y postpartum. En el periparto se identificaron, de mayor a menor frecuencia, las siguientes complicaciones: analgesia lateralizada (16,4%, punción hemática (8,7%, parestesias (8,2%, técnica dificultosa (5,2%, analgesia ineficaz (2,7%, hipotensión arterial (2,5% y bloqueo subdural (0,2%. En el postparto: lumbalgia (18,5%, retención urinaria (3,4%, cefalea post-punción dural (1,4%, neuropatías periféricas (0,9% e hipoestesia prolongada (0,2%. Todas las complicaciones se resolvieron ad integrum con tratamiento conservador salvo un caso de cefalea que precisó la realización de un parche hemático. Conclusiones: La alta tasa de fallos de la analgesia epidural en obstetricia así como la posibilidad de complicaciones neurológicas pueden resolverse siguiendo unas normas de buena práctica que incluyen la aspiración previa a la inyección, la dosis test y la revisión periódica del catéter. Resulta imprescindible conocer dichas complicaciones para su evaluación y tratamiento precoz.Objectives: To determine the incidence of failures and neurological complications related to the epidural analgesia for labour and to analyze their evolution and

  5. Epidural analgesia in patients with traumatic rib fractures

    DEFF Research Database (Denmark)

    Duch, P; Møller, M H

    2015-01-01

    BACKGROUND: Traumatic rib fractures are a common condition associated with considerable morbidity and mortality. Observational studies have suggested improved outcome in patients receiving continuous epidural analgesia (CEA). The aim of the present systematic review of randomised controlled trials...... (RCTs) was to assess the benefit and harm of CEA compared with other analgesic interventions in patients with traumatic rib fractures. METHODS: We performed a systematic review with meta-analysis and trial sequential analysis (TSA). Eligible trials were RCTs comparing CEA with other analgesic...... interventions in patients with traumatic rib fractures. Cumulative relative risks (RRs) and mean differences (MDs) with 95% confidence intervals (CIs) were estimated, and risk of systematic and random errors was assessed. The predefined primary outcome measures were mortality, pneumonia and duration...

  6. Controversy of the use of epidural analgesia in labour

    Directory of Open Access Journals (Sweden)

    Enrique Ramón Arbués

    2008-11-01

    Full Text Available During last years, it was thought that free-pain labour was a big advance for woman. Recently, ideological patrons such as ecofeminism have feed a critical mind in the woman who is going to give birth. In this bibliographic review we don’t approach a reliable and definitive conclusion, due to the bias and lack of scientific rigour of some studies and the doubtful methodological reliability and generalization of others.This way, we conclude the need to make a tolerant effort on the part of everyone, just as researching and assuming on the services portfolio (if needed alternative techniques such as combined spinal-epidural analgesia, sterile water injections, water immersion, acupuncture, hypnosis, etc.

  7. Labor induction just after external cephalic version with epidural analgesia at term

    Directory of Open Access Journals (Sweden)

    Marcos J. Cuerva

    2017-06-01

    Conclusion: Considering that a high number of cesarean deliveries can be avoided, induction of labor after ECV with epidural analgesia at term can be considered after being discussed in selected patient.

  8. Epidural Labor Analgesia Is Associated with a Decreased Risk of Postpartum Depression: A Prospective Cohort Study

    National Research Council Canada - National Science Library

    Ding, Ting; Wang, Dong-Xin; Qu, Yuan; Chen, Qian; Zhu, Sai-Nan

    2014-01-01

    .... The etiology remains unclear, and multiple factors may be involved. In this study, we investigated whether epidural labor analgesia was associated with a decreased risk of postpartum depression development...

  9. Postoperative pain and gastro-intestinal recovery after colonic resection with epidural analgesia and multimodal rehabilitation

    DEFF Research Database (Denmark)

    Werner, M U; Gaarn-Larsen, L; Basse, L;

    2005-01-01

    and ten consecutive patients scheduled for elective open colonic resection under general anaesthesia with combined thoracic epidural analgesia were prospectively studied. Postoperative epidural analgesia was maintained for 48 h with bupivacaine 2.5 mg/ml and morphine 50 µg/ml, 4 ml/h. Postoperative pain......The aim of the study was to evaluate initial postoperative pain intensity and the association with recovery of gastrointestinal function and length of stay (LOS) in a multimodal programme with epidural analgesia, early oral nutrition and mobilisation with a 48 h planned hospital stay. One hundred......, respectively. Gastrointestinal recovery and LOS did not differ between patients with high (3-6) versus low (0-2) dynamic pain scores (P > 0.4 and P > 0.1, respectively). It is concluded that a multimodal rehabilitation program including continuous thoracic epidural analgesia leads to early recovery...

  10. [Labor epidural analgesia for a woman with a pityriasis versicolor in the lumbar region].

    Science.gov (United States)

    Dubar, G; Omarjee, M; Viguié, C; Barbarot, S; Mignon, A

    2011-01-01

    Epidural analgesia is usually contraindicated in case of infection at the site of needle insertion. Tinea versicolor is a benign superficial cutaneous fungal infection caused by the proliferation of a skin commensal yeast of low pathogenicity. We report the case of a pregnant woman with a tinea versicolor in the lumbar region, who benefited from a labor epidural analgesia, realised with reinforced antiseptic measures. No neurological or infectious complication occurred.

  11. Comparison of parenteral tramadol and epidural ropivacaine for labour analgesia: a prospective clinical study

    Directory of Open Access Journals (Sweden)

    Akanksha Lamba

    2016-06-01

    Conclusions: Maternal outcome in labour analgesia is similar with 100 mg I/M tramadol and epidural ropivacaine. There is no significant difference between duration of labour, rate of LSCS, incidence of instrumental delivery and neonatal outcome in the two modes of analgesia. Analgesic efficacy with epidural ropivacaine seems to be better compared to intramuscular tramadol. [Int J Reprod Contracept Obstet Gynecol 2016; 5(6.000: 1722-1727

  12. Inserting epidural patient controlled analgesia into a peripheral venous line.

    Science.gov (United States)

    2016-01-01

    A case is reported from the Safety Reporting System in Anaesthesia and Resuscitation database. The event occurred in a patient undergoing abdominal surgery in whom an epidural catheter was inserted for analgesia. After the intervention, the patient was transferred to the recovery unit where the patient controlled analgesia (PCA) is programmed. Due to an error, the PCA was connected to a peripheral venous line, which was detected early without harm to the patient. Communication and analysis of this incident served to introduce a new drug delivery protocol through PCA pumps, including the obligation to prescribe the PCA in the electronic system, a dual computerised check immediately before connecting PCA, labelling the medication bag as well as the proximal and distal lines, standardisation of daily visits to patients, and monthly monitoring of results. Copyright © 2016 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  13. The effect of epidural analgesia in labour on maternal respiratory function.

    Science.gov (United States)

    von Ungern-Sternberg, B S; Regli, A; Bucher, E; Reber, A; Schneider, M C

    2004-04-01

    Lumbar epidural analgesia during labour has gained widespread acceptance. The impact of epidural analgesia based on mixtures of low-dose local anaesthetic solutions and lipophilic opioids on most clinically relevant obstetric outcomes is minimal. Since the pregnant state per se is associated with important alterations in respiration, we assessed whether a subtle degree of motor blockade brought about by epidural analgesia might compromise respiratory function as assessed by spirometry. Sixty consenting parturients receiving epidural analgesia were consecutively included in this prospective study. We performed spirometry during the antepartum visit and in labour after effective epidural analgesia was established; at both assessments the women were pain-free. Values were within normal ranges but increased significantly after effective epidural analgesia; median (IQR [range]) increase for vital capacity 7.4 (3.0-13 [-12-27])% (p forced vital capacity 4.4 (1.7-9.8 [-13-26])% (p forced expiratory volume in 1 s 5.5 (1.7-8.6 [-14-28])% (p labour significantly improved respiratory function.

  14. Does epidural sufentanil provide effective analgesia per- and postoperatively for abdominal aortic surgery?

    NARCIS (Netherlands)

    Broekema, AA; Kuizenga, K; Hennis, PJ

    1996-01-01

    assess the efficacy of epidural sufentanil in providing per- and postoperative analgesia, 40 patients undergoing elective abdominal aortic surgery received either 50 mu g sufentanil in 10 ml normal saline solution (n=20, ES group) or 10 mi normal saline (n=20, control group) via a thoracic epidural

  15. [Epidural anesthesia and analgesia in the perioperative treatment of a patient with Kartagener syndrome].

    Science.gov (United States)

    Errando, C L; Sifre, C; López-Alarcón, D

    1998-12-01

    Kartagener's syndrome is an inherited disease characterized by a triad of symptoms--bronchiectasis, situs inversus and sinusitis--and is classified as an immotile cilia syndrome. Patients may experience specific airway problems when undergoing anesthesia for surgical procedures. We report the case of a woman with Kartagener's syndrome who underwent surgery under epidural anesthesia with postoperative epidural analgesia, both techniques proving successful.

  16. Predicting early epidurals: association of maternal, labor, and neonatal characteristics with epidural analgesia initiation at a cervical dilation of 3 cm or less

    Directory of Open Access Journals (Sweden)

    Moore AR

    2013-08-01

    Full Text Available Albert R Moore, William Li Pi Shan, Roupen Hatzakorzian Department of Anaesthesia, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada Background: Retrospective studies have associated early epidural analgesia with cesarean delivery, but prospective studies do not demonstrate a causal relationship. This suggests that there are other variables associated with early epidural analgesia that increase the risk of cesarean delivery. This study was undertaken to determine the characteristics associated with early epidural analgesia initiation. Methods: Information about women delivering at 37 weeks or greater gestation with epidural analgesia, who were not scheduled for cesarean delivery, was extracted from the McGill Obstetric and Neonatal Database. Patients were grouped into those who received epidural analgesia at a cervical dilation of ≤3 cm and >3 cm. Univariable and multivariable logistic regression was used to determine the maternal, neonatal, and labor characteristics that increased the risk of inclusion in the early epidural group. Results: Of the 13,119 patients analyzed, multivariable regression demonstrated odds ratios (OR of 2.568, 5.915 and 10.410 for oxytocin augmentation, induction, and dinoprostone induction of labor (P < 0.001. Increasing parity decreased the odds of early epidural analgesia (OR 0.780, P < 0.001, while spontaneous rupture of membranes (OR 1.490 and rupture of membranes before labor commenced (OR 1.288 were also associated with early epidural analgesia (P < 0.001. Increasing maternal weight (OR 1.049, P = 0.002 and decreasing neonatal weight (OR 0.943, P < 0.001 were associated with increasing risk of early epidural analgesia. Conclusion: Labor augmentation and induction, nulliparity, rupture of membranes spontaneously and before labor starts, increasing maternal weight, and decreasing neonatal weight are associated with early epidural analgesia. Many of these variables are also

  17. Labour epidural analgesia audit in a tertiary state hospital in South ...

    African Journals Online (AJOL)

    the epidural analgesia records could be retrieved for analysis. The figure ... midline approach (98%) with loss of resistance to saline (70.5%). Follow up ... were preeclampsia (36.2%), body mass index (BMI) exceeding. 45 kg/m2 ... NYHA II exercise tolerance. .... analgesia influenced the mode of delivery, because the audit.

  18. Neostigmine Decreases Bupivacaine Use by Patient-Controlled Epidural Analgesia During Labor: A Randomized Controlled Study

    Science.gov (United States)

    Ross, Vernon H.; Pan, Peter H.; Owen, Medge D; Seid, Melvin H.; Harris, Lynne; Clyne, Brittany; Voltaire, Misa; Eisenach, James C.

    2009-01-01

    Background Intrathecal neostigmine produces analgesia, but also severe nausea. In contrast, epidural neostigmine enhances opioid and local anesthetic analgesia without causing nausea. Previous studies examined only single epidural neostigmine bolus administration and did not assess the efficacy of continuous epidural infusion or several aspects of maternal and fetal safety. We therefore tested the hypothesis that epidural neostigmine in combination with bupivacaine by continuous infusion during labor would reduce the amount of bupivacaine required. Methods Twelve healthy women scheduled for elective cesarean delivery were assigned to receive epidural neostigmine, 40 μg (first 6 subjects) or 80 μg (second 6 subjects) as a single bolus, with fetal heart rate and uterine contractions monitored for 20 minutes. In a subsequent experiment, 40 healthy laboring women were randomized to receive bupivacaine 1.25 mg/mL alone or with neostigmine 4 μg/mL by patient-controlled epidural analgesia. The primary outcome measure was hourly bupivacaine use. Results Epidural neostigmine bolus did not alter baseline fetal heart rate, induce contractions or produce nausea. Epidural neostigmine infusion reduced bupivacaine requirement by 19% in all patients and 25% in those with > 4 hours of treatment (P<0.05 for both), but might have contributed to the incidence of mild sedation. Mode of delivery, incidence of maternal nausea and fetal heart rate abnormality were similar between groups. Conclusions These data show that adding epidural neostigmine 4 μg/mL reduces the hourly bupivacaine requirement by 19% to 25% with patient-controlled epidural analgesia during labor. Administered as a bolus and by continuous infusion at the studied doses, epidural neostigmine does not cause nausea and does not induce uterine contractions or fetal heart rate abnormalities, but mild sedation can occur. PMID:19377050

  19. COMPARATIVE STUDY BETWEEN EPIDURAL BUPIVACAINE WITH BUPRENORPHINE AND EPIDURAL BUPIVACAINE FOR POST - OPERATIVE ANALGESIA IN ABDOMINAL AND LOWER LIMB SURGERY

    Directory of Open Access Journals (Sweden)

    Nagesh

    2015-02-01

    Full Text Available Epidural administration of various analgesics gained increasing popularity following the discovery of opioid receptors in the spinal cord capable of producing potent analgesia. This effect seems to be greatest when epidural anaesthesia in continued in the post - operative period as epidural analgesia . It is now clear that epidural administration of opioids. Ours was a comparative study between epidural bupivacaine with buprenorphine and epidural bupivacaine for post - operative analgesia in abdominal and lower limb surgery. METHODS: 60 patients undergoing lower abdominal and lower limb surgeries of either sex with ASA grade 1 and 2 a ged between 20 and 60 years for divided into two groups. After completion of the surgery and when the effect of local anaesthetic wears of and the patients complains of pain the intended study drugs were given when visual analogue pain score touched 5 cm m ark. Group – A: Patients received 8ml of 0.25% bupivacaine + 0.15mg of buprenorphine. Group – B: patients received 0.25% of bupivacaine alone. In the post - operative period the following parameters were studied , 1. Onset of analgesia , 2. Duration of analges ia , 3. Vital parameters such as heart beat , blood pressure , respiratory rate , sedation score and visual analogue score were recorded , 4. Side effects like nausea , vomiting , hypotension , respiratory depression , and pruritus allergic reaction were looked for . RESULTS: It is observed that onset of analgesia in Group A (0.25% bupivacaine + 0.15mg buprenorphine was 7.35 min. When compared to Group B which 15.5 min , which is statically significant (P<0.05. Duration of analgesia in Group A is 17.23 hrs compared to Group B , which is 5.2 hrs , this is statically significant (P<0.05. Visual analogue scale was reduced in Group A compared to Group B CONCLUSIONS: Addition of buprenorphine to bupivacaine by epidural injection for post - operative analgesia improves the on set , The duration and the

  20. Bilateral Heel Numbness due to External Compression during Obstetric Epidural Analgesia

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    Vivian P. Kamphuis

    2015-01-01

    Full Text Available We describe the case of a 32-year-old woman who developed bilateral heel numbness after obstetric epidural analgesia. We diagnosed her with bilateral neuropathy of the medial calcaneal nerve, most likely due to longstanding pressure on both heels. Risk factors for the development of this neuropathy were prolonged labour with spinal analgesia and a continuation of analgesia during episiotomy. Padded footrests decrease pressure and can possibly prevent this neuropathy.

  1. An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

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    Paulo V. M. Steagall

    2017-05-01

    Full Text Available This review aims to report an update on drugs administered into the epidural space for anesthesia and analgesia in dogs, describing their potential advantages and disadvantages in the clinical setting. Databases searched include Pubmed, Google scholar, and CAB abstracts. Benefits of administering local anesthetics, opioids, and alpha2 agonists into the epidural space include the use of lower doses of general anesthetics (anesthetic “sparing” effect, perioperative analgesia, and reduced side effects associated with systemic administration of drugs. However, the potential for cardiorespiratory compromise, neurotoxicity, and other adverse effects should be considered when using the epidural route of administration. When these variables are considered, the epidural technique is useful as a complementary method of anesthesia for preventive and postoperative analgesia and/or as part of a balanced anesthesia technique.

  2. Placental abruption occurring soon after labor combined spinal-epidural analgesia.

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    Jaime, F; Degani, J; Lam, N; Allen, G

    2012-10-01

    We present a case of placental abruption necessitating emergency cesarean section in an otherwise uncomplicated patient soon after initiation of combined spinal-epidural analgesia in labor. Administration of spinal opioids has the potential to cause fetal bradycardia due to uterine hypertonicity following rapid onset of analgesia. In this case, a previously bloody show before placement of combined spinal-epidural analgesia may have been evidence of a small abruption. We hypothesize that uterine hypertonicity following administration of spinal opioids may have hastened the development of an existing placental abruption. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. A COMPARISON OF ANALGESIA AND FOETAL OUTCOME IN TERM PARTURIENTS WITH AND WITHOUT LOW DOSE COMBINED SPINAL EPIDURAL LABOUR ANALGESIA

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    Manjunath

    2015-11-01

    Full Text Available : STUDY OBJECTIVE: We aimed to find a safe method of labor analgesia with minimal side effects and toxicity in mother and fetus using combined ‘low dose’ spinal and epidural (CSE. DESIGN: prospective case control study. SETTING: Labour suite of a tertiary care hospital. PATIENTS: study population included 120 pregnant women of ASA physical status I and II parturients in active labor who requested analgesia, 60 of these patients were given labour analgesia - ‘GROUP T’ and 60 of who underwent a delivery without labour analgesia -‘GROUP C’. MEASUREMENTS AND MAIN RESULTS: Maternal hemodynamics, degree of pain relief, duration of labour, fetal heart rate, Apgar scores, mode of delivery, intervention to relieve pain, Adverse effects because of procedure and drugs used were also noted. Low dose epidural analgesia does not prolong labour and does not increase the incidence of instrumental deliveries when compared to parturients undergoing delivery without labour analgesia. Even with the reduced dose of fentanyl the parturients had acceptable pain relief and a decreased incidence of intervention for pain. It does not cause more fetal depression when compared to normally laboring term parturients. ‘Low dose’ labour analgesia is a safe technique for painless labour with no harmful effects on the mother or baby and it does not significantly affect the obstetric outcome. CONCLUSION: ‘Low dose’ labour analgesia is a safe technique for painless labour with no harmful effects on the mother or baby and it does not significantly affect the obstetric outcome.

  4. Predicting early epidurals: association of maternal, labor, and neonatal characteristics with epidural analgesia initiation at a cervical dilation of 3 cm or less.

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    Moore, Albert R; Shan, William Li Pi; Hatzakorzian, Roupen

    2013-01-01

    Retrospective studies have associated early epidural analgesia with cesarean delivery, but prospective studies do not demonstrate a causal relationship. This suggests that there are other variables associated with early epidural analgesia that increase the risk of cesarean delivery. This study was undertaken to determine the characteristics associated with early epidural analgesia initiation. Information about women delivering at 37 weeks or greater gestation with epidural analgesia, who were not scheduled for cesarean delivery, was extracted from the McGill Obstetric and Neonatal Database. Patients were grouped into those who received epidural analgesia at a cervical dilation of ≤3 cm and >3 cm. Univariable and multivariable logistic regression was used to determine the maternal, neonatal, and labor characteristics that increased the risk of inclusion in the early epidural group. Of the 13,119 patients analyzed, multivariable regression demonstrated odds ratios (OR) of 2.568, 5.915 and 10.410 for oxytocin augmentation, induction, and dinoprostone induction of labor (P labor commenced (OR 1.288) were also associated with early epidural analgesia (P Labor augmentation and induction, nulliparity, rupture of membranes spontaneously and before labor starts, increasing maternal weight, and decreasing neonatal weight are associated with early epidural analgesia. Many of these variables are also associated with cesarean delivery.

  5. Early versus late initiation of epidural analgesia in labor: does it increase the risk of cesarean section? A randomized trial.

    Science.gov (United States)

    Ohel, Gonen; Gonen, Roni; Vaida, Sonia; Barak, Shlomi; Gaitini, Luis

    2006-03-01

    To determine whether early initiation of epidural analgesia in nulliparous women affects the rate of cesarean sections and other obstetric outcome measures. A randomized trial in which 449 at term nulliparous women in early labor, at less than 3 cm of cervical dilatation, were assigned to either immediate initiation of epidural analgesia at first request (221 women), or delay of epidural until the cervix dilated to at least 4 cm (228 women). At initiation of the epidural the mean cervical dilatation was 2.4 cm in the early epidural group and 4.6 cm in the late group (P labor, the women indicated a preference for early epidural. Initiation of epidural analgesia in early labor, following the first request for epidural, did not result in increased cesarean deliveries, instrumental vaginal deliveries, and other adverse effects; furthermore, it was associated with shorter duration of the first stage of labor and was clearly preferred by the women.

  6. Fentanyl versus tramadol with levobupivacaine for combined spinal-epidural analgesia in labor

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    Veena Chatrath

    2015-01-01

    Full Text Available Background: Neuraxial labor analgesia using new local anesthetics such as levobupivacaine has become very popular by virtue of the safety and lesser motor blockade caused by these agents. Combined spinal-epidural analgesia (CSEA has become the preferred method for labor analgesia as it combines benefits of both spinal analgesia and flexibility of the epidural catheter. Adding opioids to local anesthetic drugs provide rapid onset and prolonged analgesia but may be associated with several maternal and fetal adverse effects. The purpose of this study is to compare fentanyl and tramadol used in CSEA in terms of duration of analgesia and frequency of the adverse fetomaternal outcome. Materials and Methods: A total of 60 primiparas with a singleton pregnancy in active labor were given CSEA after randomly allocating them in two groups of 30 each. Group I received intrathecal 2.5 mg levobupivacaine + 25 μg fentanyl followed by epidural top ups of 20 ml 0.125% solution of the same combination. Group II received 25 mg tramadol instead of fentanyl. Epidural top ups were given when parturient complained of two painful contractions (visual analogue scale ≥ 4. Data collected were demographic profile of the patients, analgesic qualities, side- effects and the fetomaternal outcome. Results: Patients in Group II had significantly prolonged analgesia (145 ± 9 minutes than in Group I (95 ± 7 minutes. Patients receiving fentanyl showed rapid onset of analgesia, but there were more incidence of side-effects like shivering, pruritus, transient fetal bradycardia, hypotension, nausea and vomiting. Only side-effect in the tramadol group was nausea and vomiting. During labor, maternal satisfaction was excellent. Conclusions: Adding tramadol to local anesthetic provides prolonged analgesia with minimal side effects. Fentanyl, when used as adjuvant to local anesthetic, has a rapid onset of analgesia but has certain fetomaternal side-effects.

  7. A prospective, randomized, blinded-endpoint, controlled study - continuous epidural infusion versus programmed intermittent epidural bolus in labor analgesia

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    Joana Nunes

    Full Text Available Abstract Background: There is evidence that administration of a programmed intermittent epidural bolus (PIEB compared to continuous epidural infusion (CEI leads to greater analgesia efficacy and maternal satisfaction with decreased anesthetic interventions. Methods: In this study, 166 women with viable pregnancies were included. After an epidural loading dose of 10 mL with Ropivacaine 0.16% plus Sufentanil 10 µg, parturient were randomly assigned to one of three regimens: A - Ropivacaine 0.15% plus Sufentanil 0.2 µg/mL solution as continuous epidural infusion (5 mL/h, beginning immediately after the initial bolus; B - Ropivacaine 0.1% plus Sufentanil 0.2 µg/mL as programmed intermittent epidural bolus and C - Same solution as group A as programmed intermittent epidural bolus. PIEB regimens were programmed as 10 mL/h starting 60 min after the initial bolus. Rescue boluses of 5 mL of the same solution were administered, with the infusion pump. We evaluated maternal satisfaction using a verbal numeric scale from 0 to 10. We also evaluated adverse, maternal and neonatal outcomes. Results: We analyzed 130 pregnants (A = 60; B = 33; C = 37. The median verbal numeric scale for maternal satisfaction was 8.8 in group A; 8.6 in group B and 8.6 in group C (p = 0.83. We found a higher caesarean delivery rate in group A (56.7%; p = 0.02. No differences in motor block, instrumental delivery rate and neonatal outcomes were observed. Conclusions: Maintenance of epidural analgesia with programmed intermittent epidural bolus is associated with a reduced incidence of caesarean delivery with equally high maternal satisfaction and no adverse outcomes.

  8. Postoperative Paraplegia as a Result of Undiagnosed Primitive Neuroectodermal Tumor, Not Epidural Analgesia

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    Pei-Ching Hung

    2007-10-01

    Full Text Available Postoperative paraplegia is a rare complication after epidural analgesia and often occurs with spinal hematoma or cord injury. We present the case of a 16-year-old girl who suffered from a tumor mass in the neck and abdomen who underwent gynecologic operation. Preoperatively, liver metastasis was found by computed tomography. Pathologic findings revealed that the abdominal mass was an ovarian dermoid cyst. After the operation, the patient complained of paraplegia while receiving epidural analgesia for postoperative pain control. A peripheral primitive neuroectodermal tumor in the thoracic and lumbar spines with spinal cord compression was later detected using magnetic resonance imaging. Learning from this case, we suggest that when a patient is preoperatively diagnosed with tumor metastasis, back pain and soreness, spinal cord compression from tumor metastasis should be excluded before epidural analgesia is implemented.

  9. Do antenatal education classes decrease use of epidural analgesia during labour? – a Danish RCT

    DEFF Research Database (Denmark)

    Brixval, Carina Sjöberg; Thygesen, Lau Caspar; Axelsen, Solveig Forberg;

    , and reduce fear during birth which in turn may decrease use of pain relief. Few randomised trials have examined the effect of attending antenatal education in small groups on use of epidural analgesia and among these conclusions are conflicting. The objective of this study was therefore to examine the effect......Background: Epidural analgesia is widely used as pain relief during labour but has negative side effects, such as prolonged labour and increased risk of obstetric interventions. Antenatal education in small groups may increase trust in own ability to cope at home in the early stages of labour...... on whether to implement the NEWBORN program in a clinical setting also depend upon the trial effect on psycho-social outcomes which will be analysed in near future. Main messages (max 200 anslag): 1. No effect of antenatal education in small groups on use of epidural analgesia as pain relief during labour...

  10. Ethnic differences in the use of intrapartum epidural analgesia

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    Jiménez-Puente Alberto

    2012-07-01

    Full Text Available Abstract Background Obstetric epidural analgesia (EA is widely applied, but studies have reported that its use may be less extensive among immigrant women or those from minority ethnic groups. Our aim was to examine whether this was the case in our geographic area, which contains an important immigrant population, and if so, to describe the different components of this phenomenon. Methods Cross-sectional observational study. Setting: general acute care hospital, located in Marbella, southern Spain. Analysis of computer records of deliveries performed from 2004 to 2010. Comparison of characteristics of deliveries according to the mothers’ geographic origins and of vaginal deliveries noting whether EA was received, using univariate and bivariate statistical analysis and multiple logistic regression (MLR. Results A total of 21,034 deliveries were recorded, and 37.4% of these corresponded to immigrant women. EA was provided to 61.1% of the Spanish women and to 51.5% of the immigrants, with important variations according to geographic origin: over 52% of women from other European countries and South America received EA, compared with around 45% of the African women and 37% of the Asian women. These differences persisted in the MLR model after adjusting for the mother's age, type of labor initiation, the weight of the neonate and for single or multiple gestation. With the Spanish patients as the reference category, all the other countries of origin presented lower probabilities of EA use. This was particularly apparent for the patients from Asia (OR 0.38; 95%CI 0.31-0.46, Morocco (OR 0.49; 95%CI 0.43-0.54 and other Africa (OR 0.55; 95%CI 0.37-0.81. Conclusions We observed a different use of EA in vaginal deliveries, according to the geographic origin of the women. The explanation for this involves a complex set of factors, depending both on the patient and on the healthcare staff.

  11. Analgesia epidural com clonidina ou romifidina em cães submetidos à cirurgia coxofemoral Epidural analgesia with clonidine or romifidine in dogs submitted to coxofemoral surgery

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    J.T. Brondani

    2004-04-01

    Full Text Available Avaliaram-se as alterações cardiorrespiratórias e a analgesia da administração epidural de clonidina ou romifidina em cães submetidos à cirurgia coxofemural. Foram utilizados 14 cães distribuídos em dois grupos: o grupo Cloni recebeu 150µg de clonidina e o grupo Romi, 20µg/kg de romifidina. A indução anestésica foi realizada com propofol e a anestesia cirúrgica mantida com halotano e O2 em respiração espontânea. A punção do espaço epidural foi feita logo após a indução. Antes da indução e a cada 10 minutos foram avaliadas as freqüências cardíaca e respiratória, a pressão arterial sistólica, a saturação de oxigênio da hemoglobina e a concentração de halotano. Após indução e ao término do procedimento cirúrgico coletou-se sangue arterial para avaliação gasométrica de pH, PaCO2, PaO2, SaO2, BE e HCO3-. Foi realizada avaliação pós-operatória do grau de analgesia (intensa, pouco intensa e inadequada nas primeiras duas horas após término da cirurgia. Os animais do grupo Romi apresentaram bradicardia, bradiarritmias e hipertensão. A freqüência cardíaca e a pressão arterial sistólica no grupo Cloni mantiveram-se dentro da faixa de variação fisiológica para a espécie. A analgesia trans-operatória foi considerada intensa nos dois grupos. A administração epidural de clonidina ou romifidina produziu intensa analgesia transcirúrgica sem depressão respiratória e pouco intensa analgesia pós-operatória por duas horasCardiovascular alterations and analgesia in 14 dogs submitted to epidural administration of clonidine or romifidine to enable coxofemoral surgery were evaluated. Dogs were separated in two groups: Cloni group received 150µg of clonidine and Romi group, 20µg/kg of romifidine. Anesthetic induction was performed using propofol (8mg/kg and maintenance using halothane and O2 in spontaneous breathing. The puncture of epidural space was performed just after anesthetic induction. Heart

  12. Postoperative pain and gastro-intestinal recovery after colonic resection with epidural analgesia and multimodal rehabilitation

    DEFF Research Database (Denmark)

    Werner, M U; Gaarn-Larsen, L; Basse, L

    2005-01-01

    The aim of the study was to evaluate initial postoperative pain intensity and the association with recovery of gastrointestinal function and length of stay (LOS) in a multimodal programme with epidural analgesia, early oral nutrition and mobilisation with a 48 h planned hospital stay. One hundred......, respectively. Gastrointestinal recovery and LOS did not differ between patients with high (3-6) versus low (0-2) dynamic pain scores (P > 0.4 and P > 0.1, respectively). It is concluded that a multimodal rehabilitation program including continuous thoracic epidural analgesia leads to early recovery...

  13. Caudal epidural analgesia using lidocaine alone or in combination with ketamine in dromedary camels (Camelus dromedarius

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    Omid Azari

    2014-02-01

    Full Text Available This study was performed to investigate the analgesic effect of lidocaine and a combination of lidocaine and ketamine following epidural administration in dromedary camels. Ten 12–18-month-old camels were randomly divided into two equal groups. In group L, the animals received 2% lidocaine (0.22 mg/kg and in group LK the animals received a mixture of 10% ketamine (1 mg/kg and 2% lidocaine (0.22 mg/kg administered into the first intercoccygeal (Co1–Co2 epidural space while standing. Onset time and duration of caudal analgesia, sedation level and ataxia were recorded after drug administration. Data were analysed by U Mann-Whitney tests and significance was taken as p < 0.05. The results showed that epidural lidocaine and co-administration of lidocaine and ketamine produced complete analgesia in the tail, anus and perineum. Epidural administration of the lidocaine-ketamine mixture resulted in mild to moderate sedation, whilst the animals that received epidural lidocaine alone were alert and nervous during the study. Ataxia was observed in all test subjects and was slightly more severe in camels that received the lidocaine-ketamine mixture. It was concluded that epidural administration of lidocaine plus ketamine resulted in longer caudal analgesia in standing conscious dromedary camels compared with the effect of administering lidocaine alone.

  14. Combined epidural-spinal opioid-free anaesthesia and analgesia for hysterectomy

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    Callesen, T; Schouenborg, Lars Øland; Nielsen, D;

    1999-01-01

    Postoperative nausea and vomiting (PONV) are major problems after gynaecological surgery. We studied 40 patients undergoing total abdominal hysterectomy, allocated randomly to receive opioid-free epidural-spinal anaesthesia or general anaesthesia with continuous epidural bupivacaine 15 mg h-1...... or continuous bupivacaine 10 mg h-1 with epidural morphine 0.2 mg h-1, respectively, for postoperative analgesia. Nausea, vomiting, pain and bowel function were scored on 4-point scales for 3 days. Patients undergoing general anaesthesia had significantly higher nausea and vomiting scores (P

  15. Bilateral interpleural versus lumbar epidural bupivacaine-morphine analgesia for upper abdominal surgery.

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    Demian, Atef D; Wahba, Ashraf M; Atia, Emad M; Hussein, Sami H

    2003-10-01

    This randomized study was designed to compare the effectiveness of bilateral interpleural analgesia with lumbar epidural analgesia, on postoperative pain relief in upper abdominal surgery. The studied patients were randomely allocated into either interpleural group "IP" (n = 15) or epidural group "EP" (n = 15). In "IP" group, preanesthetic bilateral interpleural block was done using a mixture of bupivacaine 0.5% (0.8 mg/kg) and 2 mg morphine diluted to 50 ml saline for each side. In "EP" group, the same mixture-diluted in 20 ml saline-was injected in the epidural space (L2-3). The general anesthetic technique was the same in both groups. Hemodynamic, gasometric, verbal pain score (VPS) values and complications were compared in both techniques. Heart rate (HR) and mean arterial pressure (MAP) readings were in the accepted normal range in the perioperative period although significant lower readings were detected in "EP" group. No significant differences were displayed in blood gasometric variables between the two groups. There were considerable level of analgesia in both groups in the postoperative period although "EP" analgesia was superior to "IP". More pain free patients (9 versus 4) and significant lower consumption of nalbuphine were detected in "EP" group. The results of this study indicate that bilateral "IP" analgesia may offer a satisfactory analgesia for upper abdominal surgery when the use of other analgesic techniques may be contraindicated.

  16. Maternal and foetal outcome after epidural labour analgesia in high-risk pregnancies

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    Sukhen Samanta

    2016-01-01

    Full Text Available Background and Aims: Low concentration local anaesthetic improves uteroplacental blood flow in antenatal period and during labour in preeclampsia. We compared neonatal outcome after epidural ropivacaine plus fentanyl with intramuscular tramadol analgesia during labour in high-risk parturients with intrauterine growth restriction of mixed aetiology. Methods: Forty-eight parturients with sonographic evidence of foetal weight <1.5 kg were enrolled in this non-randomized, double-blinded prospective study. The epidural (E group received 0.15% ropivacaine 10 ml with 30 μg fentanyl incremental bolus followed by 7–15 ml 0.1% ropivacaine with 2 μg/ml fentanyl in continuous infusion titrated until visual analogue scale was three. Tramadol (T group received intramuscular tramadol 1 mg/kg as bolus as well as maintenance 4–6 hourly. Neonatal outcomes were measured with cord blood base deficit, pH, ionised calcium, sugar and Apgar score after delivery. Maternal satisfaction was also assessed by four point subjective score. Results: Baseline maternal demographics and neonatal birth weight were comparable. Neonatal cord blood pH, base deficit, sugar, and ionised calcium levels were significantly improved in the epidural group in comparison to the tramadol group. Maternal satisfaction (P = 0.0001 regarding labour analgesia in epidural group was expressed as excellent by 48%, good by 52% whereas it was fair in 75% and poor in 25% in the tramadol group. Better haemodynamic and pain scores were reported in the epidural group. Conclusion: Epidural labour analgesia with low concentration local anaesthetic is associated with less neonatal cord blood acidaemia, better sugar and ionised calcium levels. The analgesic efficacy and maternal satisfaction are also better with epidural labour analgesia.

  17. Intravenous remifentanil versus epidural ropivacaine with sufentanil for labour analgesia: a retrospective study.

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    Rong Lin

    Full Text Available Remifentanil with appropriate pharmacological properties seems to be an ideal alternative to epidural analgesia during labour. A retrospective cohort study was undertaken to assess the efficacy and safety of remifentanil intravenous patient-controlled analgesia (IVPCA compared with epidural analgesia. Medical records of 370 primiparas who received remifentanil IVPCA or epidural analgesia were reviewed. Pain and sedation scores, overall satisfaction, the extent of pain control, maternal side effects and neonatal outcome as primary observational indicators were collected. There was a significant decline of pain scores in both groups. Pain reduction was greater in the epidural group throughout the whole study period (0 ∼ 180 min (P < 0.0001, and pain scores in the remifentanil group showed an increasing trend one hour later. The remifentanil group had a lower SpO2 (P < 0.0001 and a higher sedation score (P < 0.0001 within 30 min after treatment. The epidural group had a higher overall satisfaction score (3.8 ± 0.4 vs. 3.7 ± 0.6, P = 0.007 and pain relief score (2.9 ± 0.3 vs. 2.8 ± 0.4, P < 0.0001 compared with the remifentanil group. There was no significant difference on side effects between the two groups, except that a higher rate of dizziness (1% vs. 21.8%, P < 0.0001 was observed during remifentanil analgesia. And logistic regression analysis demonstrated that nausea, vomiting were associated with oxytocin usage and instrumental delivery, and dizziness was associated to the type and duration of analgesia. Neonatal outcomes such as Apgar scores and umbilical-cord blood gas analysis were within the normal range, but umbilical pH and base excess of neonatus in the remifentanil group were significantly lower. Remifentanil IVPCA provides poorer efficacy on labor analgesia than epidural analgesia, with more sedation on parturients and a trend of newborn acidosis. Despite these adverse effects, remifentanil IVPCA can still be an alternative

  18. Lumbosacral epidural magnesium prolongs ketamine analgesia in conscious sheep Sulfato de magnésio prolonga a analgesia epidural lombosacral induzida pela quetamina em carneiros

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    Rafael DeRossi

    2012-02-01

    Full Text Available PURPOSE: To determine the analgesic, motor, sedation and systemic effects of lumbosacral epidural magnesium sulphate added to ketamine in the sheep. METHODS: Six healthy adult male mixed-breed sheep; weighing 43 ± 5 kg and aged 20-36 months. Each sheep underwent three treatments, at least 2 weeks apart, via epidural injection: (1 ketamine (KE; 2.5 mg/kg, (2 magnesium sulphate (MG; 100 mg, and (3 KE + MG (KEMG; 2.5 mg/kg + 100 mg, respectively. Epidural injections were administered through the lumbosacral space. Analgesia, motor block, sedation, cardiovascular effects, respiratory rate, skin temperature, and rectal temperature were evaluated before (baseline and after drug administration as needed. RESULTS: The duration of analgesia with the lumbosacral epidural KEMG combination was 115 ± 17 min (mean ± SD, that is, more than twice that obtained with KE (41 ± 7 min or MG (29 ± 5 min alone. KE and KEMG used in this experiment induced severe ataxia. The heart rate and arterial blood pressures changes were no statistical difference in these clinically health sheep. CONCLUSION: The dose of magnesium sulphate to lumbosacral epidural ketamine in sheep is feasible, and can be used in procedures analgesics in sheep.OBJETIVO: Determinar os efeitos analgésicos, motores, sedativos e sistêmicos da adição de sulfato de magnésio na analgesia epidural com quetamina em carneiros. MÉTODOS: Foram utilizados seis carneiros machos sadios, pesando 43 ± 5 kg, com idade entre 20 a 36 meses. Cada animal recebeu três tratamentos, com duas semanas entre experimentos via administração epidural: (1 quetamina (KE; 2,5 mg/kg, (2 sulfato de magnésio (MG; 100 mg e (3 KE + MG (KEMG; 2,5 mg/kg + 100 mg, respectivamente. As administrações epidurais foram administradas no espaço lombosacral. Analgesia, bloqueio motor, sedação, efeitos cardiovasculares, freqüência respiratória, temperatura retal e de pele foram avaliados antes (basal e depois da administra

  19. Patient Controlled Epidural Analgesia during Labour: Effect of Addition of Background Infusion on Quality of Analgesia & Maternal Satisfaction

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    Uma Srivastava

    2009-01-01

    Full Text Available Patient controlled epidural analgesia (PCEA is a well established technique for pain relief during labor. But the inclusion of continuous background infusion to PCEA is controversial. The aim of this study was to assess whether the use of continuous infusion along with PCEA was beneficial for laboring women with regards to quality of analgesia, maternal satisfaction and neonatal outcome in comparison to PCEA alone. Fifty five parturients received epidural bolus of 10ml solution containing 0.125% bupivacaine +2 ìg.ml-1 of fentanyl. For maintenance of analgesia the patients of Group PCEA self administered 8 ml bolus with lockout interval of 20 minutes of above solution on demand with no basal infusion. While the patients of Group PCEA + CI received continuous epidural infusion at the rate of 10 ml.hr-1 along with self administered boluses of 3 ml with lockout interval of 10 minutes of similar epidural solution. Patients of both groups were given rescue boluses by the anaesthetists for distressing pain. Verbal analogue pain scores, incidence of distressing pain, need of supplementary/rescue boluses, dose of bupivacaine consumed, maternal satisfaction and neonatal Apgar scores were recorded. No significant difference was observed between mean VAS pain scores during labor, maternal satisfaction, mode of delivery or neonatal Apgar scores. But more patients (n=8 required rescue boluses in PCEA group for distressing pain. The total volume consumed of bupivacaine and opioid was slightly more in PCEA + CI group. In both the techniques the highest sensory level, degree of motor block were comparable& prolongation of labor was not seen. It was concluded that both the techniques provided equivalent labor analgesia, maternal satisfaction and neonatal Apgar scores. PCEA along with continuous infusion at the rate of 10 ml/ hr resulted in lesser incidence of distressing pain and need for rescue analgesic. Although this group consumed higher dose of bupivacaine

  20. Estudio descriptivo de la analgesia obtenida durante el trabajo de parto con PCA de remifentanilo: modelo británico

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    C. Morales Muñoz

    2014-12-01

    Full Text Available Introducción: la analgesia epidural obstétrica continúa siendo el "gold-standard" para controlar el dolor durante el trabajo de parto, pero en determinadas ocasiones la técnica está contraindicada o la analgesia es incompleta. El remifentanilo es un opioide potente de rápida acción y vida media ultracorta, que se adapta perfectamente a la dinámica del parto. La coordinación entre el comienzo de las contracciones y la administración del fármaco mediante un dispositivo PCA hacen que esta técnica pueda ser considerada de elección para el alivio de dolor durante el parto y no solo como alternativa a la epidural. Objetivo: este estudio pretende valorar la eficacia y seguridad en el parto del remifentanilo administrado por vía intravenosa, así como la satisfacción materna de la analgesia recibida. Materiales y métodos: estudio descriptivo prospectivo basado en el análisis de la recogida de datos realizado por los investigadores durante el parto donde se recoge el dolor durante la dilatación y el expulsivo antes y después de la aplicación de la PCA de remifentanilo, así como las complicaciones y la incidencia de efectos secundarios. Paralelamente se realiza una encuesta de satisfacción materna de la técnica recibida y su vivencia personal. Resultados: se han recogido un total de 32 casos durante el periodo de estudio (6 meses. Todas las pacientes han presentado una reducción de dolor manifestado por una disminución del EVA respecto del dolor basal de 5,9 puntos en los primeros minutos, 4,6 puntos en completa y 3,4 en el expulsivo. No se han registrado complicaciones materno-fetales importantes derivadas de la técnica. La satisfacción materna ha sido alta, volviendo incluso a repetir la técnica en un 90 % de los casos. Conclusiones: la PCA de remifentanilo ha demostrado ser efectiva y segura como analgesia obstétrica. Es por ello que la PCA ha teniendo una amplia aceptación entre matronas, ginecólogos y anestesiólogos en

  1. Combined spinal epidural (CSE) analgesia: technique, management, and outcome of 300 mothers.

    Science.gov (United States)

    Collis, R E; Baxandall, M L; Srikantharajah, I D; Edge, G; Kadim, M Y; Morgan, B M

    1994-04-01

    Epidural analgesia in labour is commonly associated with some degree of lower limb weakness often severe enough to be described as paralysis by the mother. We aimed to produce rapid reliable analgesia with no motor block throughout labour. We report a pilot survey of 300 consecutive women requesting regional analgesia in labour who received a combined spinal epidural blockade (CSE). The initial dose was given into the subarachnoid space and analgesia maintained via an epidural catheter. A subarachnoid injection of 2.5 mg bupivacaine and 25 mug fentanyl was successfully given in 268 women (89.3%). Completely pain-free contractions within 3 min of this injection occurred in 195 women (65%) and in all 300 within 20 min and there was no associated motor block in 291 (97%). 141 women chose to stand, walk or sit in a rocking chair at some time during labour. Only 38 women (12.6%) were immobile during the first stage of labour. Analgesia was maintained via the epidural catheter with bolus doses of 10-15 ml of 0.1% bupivacaine and 0.0002% fentanyl. The mean bupivacaine requirement was 9.5 mg/h throughout the entire duration of analgesia. The incidence of post lumbar puncture headache was 2.3%. Transient hypotension occurred in 24 women (8%) and was treated with 6 mg intravenous boluses of ephedrine. Complete satisfaction with analgesia and mobility was reported 12-24 h post partum by 95% of mothers. The use of this analgesic technique caused no alteration in obstetric management or post partum care of the women.

  2. Postoperative analgesia with continuous epidural sufentanil and bupivacaine : A prospective study in 614 patients

    NARCIS (Netherlands)

    Broekema, AA; Gielen, MJM; Hennis, PJ

    1996-01-01

    To assess the efficacy and safety of postoperative analgesia with continuous epidural sufentanil and bupivacaine, we performed a prospective study in 614 patients undergoing major surgery. Before surgical incision, all patients received an initial dose of 50 mu g sufentanil in 6-10 mL bupivacaine 0.

  3. Effect of ropivacaine in combined with sufentanil epidural analgesia after cesarean section on maternal lactation

    Institute of Scientific and Technical Information of China (English)

    Hu Feng; Bao-Xia Chen; Xi Ren; Hong-Xia Zhu

    2016-01-01

    Objective:To observe the effect of application of ropivacaine in combined with sufentanil epidural analgesia after cesarean section on the lactation and neonates.Methods:The puerpera who were underwent cesarean section with different analgesia methods were observed. The included puerpera were performed with the cesarean section under combined spinal epidural anesthesia. A total of 30 puerpera who were given ropivacaine in combined with sufentanil epidural analgesia after operation were served as the observation group, while 30 cases who were intermittently given intramuscular injection of pethidine after operation were served as the control group. The postpartum analgesic effects in the two groups were observed. The radioimmunoassay was used to detect the plasma PRL level. The postpartum colostrum time, 24 h lactation number, and NBNA scores in the two groups were compared.Results:The postoperative VAS score in the observation group was significantly lower than that in the control group (P<0.05), while the plasma PRL level was significantly higher than that in the control group (P<0.05). The postoperative colostrum time in the observation group was significantly earlier than that in the control group (P<0.05), while the lactation number was significantly greater than that in the control group (P<0.05).Conclusions:Application of ropivacaine in combined with sufentanil epidural analgesia after cesarean section can effectively alleviate the postoperative pain, and improve the lactation, with no obvious adverse reactions on the neonates and reliable effects.

  4. Frequency of colonization and isolated bacteria from the tip of epidural catheter implanted for postoperative analgesia.

    Science.gov (United States)

    Stabille, Débora Miranda Diogo; Diogo Filho, Augusto; Mandim, Beatriz Lemos da Silva; de Araújo, Lúcio Borges; Mesquita, Priscila Miranda Diogo; Jorge, Miguel Tanús

    2015-01-01

    The increased use of epidural analgesia with catheter leads to the need to demonstrate the safety of this method and know the incidence of catheter colonization, inserted postoperatively for epidural analgesia, and the bacteria responsible for this colonization. From November 2011 to April 2012, patients electively operated and maintained under epidural catheter for postoperative analgesia were evaluated. The catheter tip was collected for semiquantitative and qualitative microbiological analysis. Of 68 cultured catheters, six tips (8.8%) had positive cultures. No patient had superficial or deep infection. The mean duration of catheter use was 43.45 h (18-118) (p=0.0894). The type of surgery (contaminated or uncontaminated), physical status of patients, and surgical time showed no relation with the colonization of catheters. Microorganisms isolated from the catheter tip were Staphylococcus aureus, Pseudomonas aeruginosa and Sphingomonas paucimobilis. Postoperative epidural catheter analgesia, under these study conditions, was found to be low risk for bacterial colonization in patients at surgical wards. Copyright © 2014 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.

  5. Postoperative analgesia with continuous epidural sufentanil and bupivacaine : A prospective study in 614 patients

    NARCIS (Netherlands)

    Broekema, AA; Gielen, MJM; Hennis, PJ

    To assess the efficacy and safety of postoperative analgesia with continuous epidural sufentanil and bupivacaine, we performed a prospective study in 614 patients undergoing major surgery. Before surgical incision, all patients received an initial dose of 50 mu g sufentanil in 6-10 mL bupivacaine

  6. Effect of postoperative epidural analgesia on rehabilitation and pain after hip fracture surgery

    DEFF Research Database (Denmark)

    Foss, Nicolai Bang; Kristensen, Morten Tange; Kristensen, Billy Bjarne;

    2005-01-01

    Hip fracture surgery usually carries a high demand for rehabilitation and a significant risk of perioperative morbidity and mortality. Postoperative epidural analgesia may reduce morbidity and has been shown to facilitate rehabilitation in elective orthopedic procedures. No studies exist on the e...

  7. Epidural labor analgesia: A comparison of ropivacaine 0.125% versus 0.2% with fentanyl

    Directory of Open Access Journals (Sweden)

    Yogesh Kumar Chhetty

    2013-01-01

    Conclusion: We conclude that both the concentrations of ropivacaine (0.2% and 0.125% with fentanyl are effective in producing epidural labor analgesia. However, 0.2% concentration was found superior in terms of faster onset, prolonged duration, lesser breakthrough pain requiring lesser top-ups, and hence a lesser consumption of opioids.

  8. Posterior paramedian subrhomboidal analgesia versus thoracic epidural analgesia for pain control in patients with multiple rib fractures.

    Science.gov (United States)

    Shelley, Casey L; Berry, Stepheny; Howard, James; De Ruyter, Martin; Thepthepha, Melissa; Nazir, Niaman; McDonald, Tracy; Dalton, Annemarie; Moncure, Michael

    2016-09-01

    Rib fractures are common in trauma admissions and are associated with an increased risk of pulmonary complications, intensive care unit admissions, and mortality. Providing adequate pain control in patients with multiple rib fractures decreases the risk of adverse events. Thoracic epidural analgesia is currently the preferred method for pain control. This study compared outcomes in patients with multiple acute rib fractures treated with posterior paramedian subrhomboidal (PoPS) analgesia versus thoracic epidural analgesia (TEA). This prospective study included 30 patients with three or more acute rib fractures admitted to a Level I trauma center. Thoracic epidural analgesia or PoPS catheters were placed, and local anesthesia was infused. Data were collected including patients' pain level, adjunct morphine equivalent use, adverse events, length of stay, lung volumes, and discharge disposition. Nonparametric tests were used and two-sided p Pain rating was lower in the PoPS group (2.5 vs. 5; p = 0.03) after initial placement. Overall, there was no other statistically significant difference in pain control or use of oral morphine adjuncts between the groups. Hypotension occurred in eight patients, 75% with TEA and only 25% with PoPS. No difference was found in adverse events, length of stay, lung volumes, or discharge disposition. In patients with rib fractures, PoPS analgesia may provide pain control equivalent to TEA while being less invasive and more readily placed by a variety of hospital staff. This pilot study is limited by its small sample size, and therefore additional studies are needed to prove equivalence of PoPS compared to TEA. Therapeutic study, level IV.

  9. Systematic Review and Meta-Analysis of Epidural Analgesia Versus Different Analgesic Regimes Following Oesophagogastric Resection.

    Science.gov (United States)

    Hughes, Michael; Yim, Ivan; Deans, D A Christopher; Couper, Graeme W; Lamb, Peter J; Skipworth, Richard J E

    2017-07-24

    Effective analgesia following open oesophagogastric (OG) resection is considered a key determinant of recovery. This review aimed to compare epidural to alternative analgesic techniques in patients undergoing major open resection for OG cancer. A systematic review and meta-analysis was conducted of randomized controlled trials comparing epidural with alternative analgesic methods in open OG surgery. Primary outcome was the overall post-operative morbidity rate. Secondary outcomes included pulmonary complication rates, length of stay (LOS) and pain scores at 24 h. Six trials which comprised of 249 patients were identified (3 following gastrectomy and 3 following oesophagectomy). Following gastrectomy, secondary outcomes including pulmonary complications and dynamic pain scores at 24 h were improved in the epidural groups. No difference was observed in overall morbidity rates or LOS. Following oesophagectomy, overall morbidity rates were not reported at all. LOS was not shortened, and rest pain was not significantly different in the epidural group, but dynamic pain scores were reported to be improved. Few trials of analgesic regimen have been performed following open OG resection. In those trials that have been performed, epidural analgesia has not been shown to reduce overall morbidity. Epidural is associated with reduced pulmonary complications after gastrectomy, but no benefit has been shown after oesophagectomy. Whilst widespread investigation of minimally invasive OG techniques currently takes place, it is clear that the most effective patient pathway following open OG surgery, particularly oesophagectomy, is still not proven. Further trials are required.

  10. Combined general-epidural anesthesia with continuous postoperative epidural analgesia preserves sigmoid colon perfusion in elective infrarenal aortic aneurysm repair

    Directory of Open Access Journals (Sweden)

    Venetiana Panaretou

    2012-01-01

    Full Text Available Background: In elective open infrarenal aortic aneurysm repair the use of epidural anesthesia and analgesia may preserve splanchnic perfusion. The aim of this study was to investigate the effects of epidural anesthesia on gut perfusion with gastrointestinal tonometry in patients undergoing aortic reconstructive surgery. Methods: Thirty patients, scheduled to undergo an elective infrarenal abdominal aortic reconstructive procedure were randomized in two groups: the epidural anesthesia group (Group A, n=16 and the control group (Group B, n=14. After induction of anesthesia, a transanally inserted sigmoid tonometer was placed for the measurement of sigmoid and gastric intramucosal CO 2 levels and the calculation of regional-arterial CO 2 difference (ΔPCO 2 . Additional measurements included mean arterial pressure (MAP, cardiac output (CO, systemic vascular resistance (SVR, and arterial lactate levels. Results: There were no significant intra- and inter-group differences for MAP, CO, SVR, and arterial lactate levels. Sigmoid pH and PCO 2 increased in both the groups, but this increase was significantly higher in Group B, 20 min after aortic clamping and 10 min after aortic declamping. Conclusions: Patients receiving epidural anesthesia during abdominal aortic reconstruction appear to have less severe disturbances of sigmoid perfusion compared with patients not receiving epidural anesthesia. Further studies are needed to verify these results.

  11. Combined general–epidural anesthesia with continuous postoperative epidural analgesia preserves sigmoid colon perfusion in elective infrarenal aortic aneurysm repair

    Science.gov (United States)

    Panaretou, Venetiana; Siafaka, Ioanna; Theodorou, Dimitrios; Manouras, Andreas; Seretis, Charalampos; Gourgiotis, Stavros; Katsaragakis, Stylianos; Sigala, Fragiska; Zografos, George; Filis, Konstantinos

    2012-01-01

    Background: In elective open infrarenal aortic aneurysm repair the use of epidural anesthesia and analgesia may preserve splanchnic perfusion. The aim of this study was to investigate the effects of epidural anesthesia on gut perfusion with gastrointestinal tonometry in patients undergoing aortic reconstructive surgery. Methods: Thirty patients, scheduled to undergo an elective infrarenal abdominal aortic reconstructive procedure were randomized in two groups: the epidural anesthesia group (Group A, n=16) and the control group (Group B, n=14). After induction of anesthesia, a transanally inserted sigmoid tonometer was placed for the measurement of sigmoid and gastric intramucosal CO2 levels and the calculation of regional–arterial CO2 difference (ΔPCO2). Additional measurements included mean arterial pressure (MAP), cardiac output (CO), systemic vascular resistance (SVR), and arterial lactate levels. Results: There were no significant intra- and inter-group differences for MAP, CO, SVR, and arterial lactate levels. Sigmoid pH and PCO2 increased in both the groups, but this increase was significantly higher in Group B, 20 min after aortic clamping and 10 min after aortic declamping. Conclusions: Patients receiving epidural anesthesia during abdominal aortic reconstruction appear to have less severe disturbances of sigmoid perfusion compared with patients not receiving epidural anesthesia. Further studies are needed to verify these results. PMID:23493852

  12. Effects of epidural lidocaine analgesia on labor and delivery: A randomized, prospective, controlled trial

    Directory of Open Access Journals (Sweden)

    Nafisi Shahram

    2006-12-01

    Full Text Available Abstract Background Whether epidural analgesia for labor prolongs the active-first and second labor stages and increases the risk of vacuum-assisted delivery is a controversial topic. Our study was conducted to answer the question: does lumbar epidural analgesia with lidocaine affect the progress of labor in our obstetric population? Method 395 healthy, nulliparous women, at term, presented in spontaneous labor with a singleton vertex presentation. These patients were randomized to receive analgesia either, epidural with bolus doses of 1% lidocaine or intravenous, with meperidine 25 to 50 mg when their cervix was dilated to 4 centimeters. The duration of the active-first and second stages of labor and the neonatal apgar scores were recorded, in each patient. The total number of vacuum-assisted and cesarean deliveries were also measured. Results 197 women were randomized to the epidural group. 198 women were randomized to the single-dose intravenous meperidine group. There was no statistical difference in rates of vacuum-assisted delivery rate. Cesarean deliveries, as a consequence of fetal bradycardia or dystocia, did not differ significantly between the groups. Differences in the duration of the active-first and the second stages of labor were not statistically significant. The number of newborns with 1-min and 5-min Apgar scores less than 7, did not differ significantly between both analgesia groups. Conclusion Epidural analgesia with 1% lidocaine does not prolong the active-first and second stages of labor and does not increase vacuum-assisted or cesarean delivery rate.

  13. Epidural versus intravenous fentanyl for postoperative analgesia following orthopedic surgery: randomized controlled trial

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    Marcelo Soares Privado

    Full Text Available CONTEXT AND OBJECTIVE: Controversy exists regarding the site of action of fentanyl after epidural injection. The objective of this investigation was to compare the efficacy of epidural and intravenous fentanyl for orthopedic surgery. DESIGN AND SETTING: A randomized double-blind study was performed in Hospital São Paulo. METHODS: During the postoperative period, in the presence of pain, 29 patients were divided into two groups: group 1 (n = 14 received 100 µg of fentanyl epidurally and 2 ml of saline intravenously; group 2 (n = 15 received 5 ml of saline epidurally and 100 µg of fentanyl intravenously. The analgesic supplementation consisted of 40 mg of tenoxicam intravenously and, if necessary, 5 ml of 0.25% bupivacaine epidurally. Pain intensity was evaluated on a numerical scale and plasma concentrations of fentanyl were measured simultaneously. RESULTS: The percentage of patients who required supplementary analgesia with tenoxicam was lower in group 1 (71.4% than in group 2 (100%: 95% confidence interval (CI = 0.001-0.4360 (P = 0.001, Fisher's exact test; relative risk, RR = 0.07. Epidural bupivacaine supplementation was also lower in group 1 (14.3% than in group 2 (53.3%: 95% CI = 0.06-1.05 (P = 0.03, Fisher's exact test; RR = 0.26. There was no difference in pain intensity on the numerical scale. Mean fentanyl plasma concentrations were similar in the two groups. CONCLUSION: Intravenous and epidural fentanyl appear to have similar efficacy for reducing pain according to the numerical scale, but supplementary analgesia was needed less frequently when epidural fentanyl was used. CLINICAL TRIAL REGISTRATION NUMBER: NCT00635986

  14. Postoperative analgesia with epidural opioids after cesarean section: Comparison of sufentanil, morphine and sufentanil-morphine combination

    Directory of Open Access Journals (Sweden)

    Kalpana S Vora

    2012-01-01

    Conclusion: Epidural administration of a combination of sufentanil and morphine offered the advantage of faster onset of action and longer duration of analgesia as compared to the two drugs administered alone.

  15. A romifidine and morphine combination for epidural analgesia of the flank in cattle.

    Science.gov (United States)

    Fierheller, Erin E; Caulkett, Nigel A; Bailey, Jeremy V

    2004-11-01

    The objective of the study reported here was to determine the onset, duration, and degree of analgesia achieved with a combination of romifidine (50 microg/kg body weight [BW]) and morphine (0.1 mg/kg BW) administered epidurally. Ten adult Holstein Friesen cows were assigned to either a treatment group receiving the romifidine and morphine combination or a control group receiving 0.9% saline in a randomized, blinded, crossover design. Cows were assessed for degree of flank analgesia and systemic sedation at various time intervals over a period of 24 hours. The romifidine and morphine combination, compared with saline, provided significant analgesia for at least 10 minutes (P = 0.016) and up to 12 hours (P = 0.004) after epidural administration. Treated cows were sedate between 10 minutes (P = 0.016) and 6 hours (P = 0.002) after epidural administration. These results provide evidence for a potential cost-effective intra- and postoperative method of analgesia; however, the sedation seen in this study could be detrimental to patients expected return to the farm shortly after surgery. Further research into withdrawal times, systemic effects, and potential adverse effects are needed before an opiod and alpha2-adrenergic agonist combination can be used safely in a clinical setting.

  16. Comparison of Interpleural and Thoracic Epidural Bupivacaine with Buprenorphine for Post-Thoracotomy Analgesia

    Directory of Open Access Journals (Sweden)

    S K Mathur

    2008-01-01

    Full Text Available The study was designed to compare the efficacy of interpleural and thoracic epidural analgesia after thorac-otomy with regard to quality of analgesia and complications. Sixty patients undergoing elective thoracotomy were randomly and equally placed into either interpleural (IP or thoracic epidural (TE group. In IP group an interpleural catheter was placed in paravertebral space under direct vision during surgery and received 0.25% bupivacaine 20 ml with buprenorphine 150 mcg. In TE group an epidural catheter was inserted in the T6-7 / T7-8 interspace and received 0.25% bupivacaine 10 ml with buprenorphine 150 mcg. Dosage were repeated in both the groups to keep a VAS score < 40 for 48 hours post-operatively. Spirometry was done preoperatively and 12, 24 and 36 hours post-opera-tively. Vital parameters were monitored for 48 hours. The mean analgesia time was 331.73±94.03 min and 567.33±127.33 min in IP and TE groups respectively. The VAS score was significantly reduced within the first 30 minutes of injection in both the groups. Post injection VAS was significantly better in TE group. Mean time taken for interpleural and epidural catheter placement was 5.0±0.0 min and 33.83±3.39 min respectively. Postoperative forced expiratory volume in 1 second(FEV1, forced vital capacity (FVC and forced expiratory ratio (FER were similar in both the groups while peak expiratory flow rate (PEFR, maximal expiratory flow (MEF and F50 were slightly better in TE group. Vital parameters showed similar changes in both the groups. The TE group had more complications. Interpleural analgesia, though of shorter duration, is a safe and effective alternative technique for post-thoracotomy analgesia and has a low complication rate.

  17. Comparative evaluation of dexmedetomidine and fentanyl for epidural analgesia in lower limb orthopedic surgeries

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    Sukhminder Jit Singh Bajwa

    2011-01-01

    Full Text Available Background and Aims: Opioids as epidural adjunct to local anesthetics (LA have been in use since long and α-2 agonists are being increasingly used for similar purpose. The present study aims at comparing the hemodynamic, sedative, and analgesia potentiating effects of epidurally administered fentanyl and dexmedetomidine when combined with ropivacaine. Methods: A total of one hundred patients of both gender aged 21-56 years, American Society of Anaesthesiologist (ASA physical status I and II who underwent lower limb orthopedic surgery were enrolled into the present study. Patients were randomly divided into two groups: Ropivacaine + Dexmedetomidine (RD and Ropivacaine + Fentanyl (RF, comprising 50 patie nts each. Inj. Ropivacaine, 15 ml of 0.75%, was administered epidurally in both the groups with addition of 1 μg/kg of dexmedetomidine in RD group and 1 μg/kg of fentanyl in RF group. Besides cardio-respiratory parameters and sedation scores, various block characteristics were also observed which included time to onset of analgesia at T10, maximum sensory analgesic level, time to complete motor blockade, time to two segmental dermatomal regressions, and time to first rescue analgesic. At the end of study, data was compiled systematically and analyzed using ANOVA with post-hoc significance, Chi-square test and Fisher′s exact test. Value of P<0.05 is considered significant and P<0.001 as highly significant. Results: The demographic profile of patients was comparable in both the groups. Onset of sensory analgesia at T10 (7.12±2.44 vs 9.14±2.94 and establishment of complete motor blockade (18.16±4.52 vs 22.98±4.78 was significantly earlier in the RD group. Postoperative analgesia was prolonged significantly in the RD group (366.62±24.42 and consequently low dose consumption of local anaesthetic LA (76.82±14.28 vs 104.35±18.96 during epidural top-ups postoperatively. Sedation scores were much better in the RD group and highly significant on

  18. Combined spinal-epidural analgesia in labour: its effects on delivery outcome

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    Suneet Kaur Sra Charanjit Singh

    2016-06-01

    Full Text Available ABSTRACT BACKGROUND AND OBJECTIVES: Combined spinal-epidural (CSE has become an increasingly popular alternative to traditional labour epidural due to its rapid onset and reliable analgesia provided. This was a prospective, convenient sampling study to determine the effects of CSE analgesia on labour outcome. METHODS: One hundred and ten healthy primigravida parturients with a singleton pregnancy of ≥37 weeks gestation and in the active phase of labour were studied. They were enrolled to the CSE (n = 55 or Non-CSE (n = 55 group based on whether they consented to CSE analgesia. Non-CSE parturients were offered other methods of labour analgesia. The duration of the first and second stage of labour, rate of instrumental vaginal delivery and emergency cesarean section, and Apgar scores were compared. RESULTS: The mean duration of the first and second stage of labour was not significantly different between both groups. Instrumental delivery rates between the groups were not significantly different (CSE group, 11% versus Non-CSE group, 16%. The slightly higher incidence of cesarean section in the CSE group (16% versus 15% in the Non-CSE group was not statistically significant. Neonatal outcome in terms of Apgar score of less than 7 at 1 and 5 min was similar in both groups. CONCLUSION: There were no significant differences in the duration of labour, rate of instrumental vaginal delivery and emergency cesarean section, and neonatal outcome in parturients who received compared to those who did not receive CSE for labour analgesia.

  19. A romifidine and morphine combination for epidural analgesia of the flank in cattle

    OpenAIRE

    Fierheller, Erin E.; Caulkett, Nigel A.; Bailey, Jeremy V.

    2004-01-01

    The objective of the study reported here was to determine the onset, duration, and degree of analgesia achieved with a combination of romifidine (50 μg/kg body weight [BW]) and morphine (0.1 mg/kg BW) administered epidurally. Ten adult Holstein Friesen cows were assigned to either a treatment group receiving the romifidine and morphine combination or a control group receiving 0.9% saline in a randomized, blinded, crossover design. Cows were assessed for degree of flank analgesia and systemic ...

  20. Efficacy of the methoxyflurane as bridging analgesia during epidural placement in laboring parturient

    Directory of Open Access Journals (Sweden)

    Jamil S Anwari

    2015-01-01

    Full Text Available Background: Establishing an epidural in an agitated laboring woman can be challenging. The ideal pain control technique in such a situation should be effective, fast acting, and short lived. We assessed the efficacy of inhalational methoxyflurane (Penthrox™ analgesia as bridging analgesia for epidural placement. Materials and Methods: Sixty-four laboring women who requested epidural analgesia with pain score of ≥7 enrolled in an observational study, 56 of which completed the study. The parturients were instructed to use the device prior to the onset of uterine contraction pain and to stop at the peak of uterine contraction, repeatedly until epidural has been successfully placed. After each (methoxyflurane inhalation-uterine contraction cycle, pain, Richmond Agitation Sedation Scale (RASS, nausea and vomiting were evaluated. Maternal and fetal hemodynamics and parturient satisfaction were recorded. Results: The mean baseline pain score was 8.2 ± 1.5 which was reduced to 6.2 ± 2.0 after the first inhalation with a mean difference of 2.0 ± 1.1 (95% confidence interval 1.7-2.3, P < 0.0001, and continued to decrease significantly over the study period (P < 0.0001. The RASS scores continuously improved after each cycle (P < 0.0001. Only 1 parturient from the cohort became lightly sedated (RASS = −1. Two parturients vomited, and no significant changes in maternal hemodynamics or fetal heart rate changes were identified during treatment. 67% of the parturients reported very good or excellent satisfaction with treatment. Conclusion: Penthrox™ provides rapid, robust, and satisfactory therapy to control pain and restlessness during epidural placement in laboring parturient.

  1. [The characteristics of epidural analgesia during the removal of lumbar intervertebral disk hernias].

    Science.gov (United States)

    Arestov, O G; Solenkova, A V; Lubnin, A Iu; Shevelev, I N; Konovalov, N A

    2000-01-01

    Epidural analgesia (EA) was used in 29 patients undergoing surgical removal of lumbar discal hernia. Marcain EA with controlled medicinal sleep and non-assisted breathing allowed to perform the whole operation in 27 patients. EA may be ineffective in combination of sequestrated disk hernia with scarry adhesive process. The technique of the operation demands a single use of the anesthetic drug which is potent enough to make blockade throughout the operation up to the end.

  2. Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation

    Directory of Open Access Journals (Sweden)

    A. L. M. J. van der Knijff-van Dortmont

    2016-01-01

    Full Text Available SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour.

  3. Rates of caesarean section and instrumental vaginal delivery in nulliparous women after low concentration epidural infusions or opioid analgesia: systematic review

    OpenAIRE

    Liu, E H C; Sia, A T H

    2004-01-01

    Objective To compare the effects of low concentration epidural infusions of bupivacaine with parenteral opioid analgesia on rates of caesarean section and instrumental vaginal delivery in nulliparous women.

  4. A comprehensive analysis of continuous epidural analgesia's effect on labor and neonates in maternal hypertensive disorder patients.

    Science.gov (United States)

    Han, Bin; Xu, Mingjun

    2017-01-01

    Maternal hypertensive disorder is one of the most common and severe medical complications during pregnancy. Epidural analgesia administration is widely used during labor process. To evaluate the potential advantage or disadvantage of continuous epidural analgesia's on labor and neonates for maternal hypertensive disorder patients comprehensively. We have retrospectively analyzed 232 patients who diagnosed as maternal hypertensive disorder in our hospital since 2015. Among which, 126 patients including 28 cases of severe preeclampsia were administrated with continuous epidural analgesia (Analgesia group), the other 106 patients were untreated (Control group). We have compared the maternal age, body weight, gestational weeks, period for the first and second labor stage; the incidence of eclampsia, natural labor, cesarean section, forceps delivery and postpartum hemorrhage between these two groups respectively; furthermore, we recorded patients who received oxytocin and antihypertensive treatment during the delivery progress as well as evaluated the neonate body weight, Apgar score and performed umbilical cord blood gas analysis. Continuous epidural analgesia does not affect the first and second labor stage period (p=0.36), However, there is a significantly higher demand for oxytocin treatment (36.5% Vs 19.8%, p<0.01) and a significantly lower requirement for antihypertensive treatment (22.2% Vs 81.1%, p<0.001) in analgesia group compared to control group. We also notice that the natural delivery ratio in analgesia group is higher than control group and most importantly, continuous epidural analgesia can increase 1min Apgar score and has no other effect on neonates' body weight, umbilical cord blood gas parameters, 5min and 10min Apgar score. Our result based on a large cohort comprehensive analysis indicates that continuous epidural analgesia can benefit both maternal hypertensive disorder patients and neonates without any side effect. Copyright © 2016 International

  5. Meralgia paresthetica-like symptoms following epidural analgesia after total knee arthroplasty.

    Science.gov (United States)

    Shin, H J; Kim, Y H; Lee, H W

    2014-11-01

    Meralgia paresthetica (MP) is generally caused by entrapment of the lateral femoral cutaneous nerve (LFCN), and presents with pain and paresthesia in the anterolateral thigh. This paper describes a patient who had MP-like symptoms as a result of continuous epidural analgesia after total knee arthroplasty. The patient with pre-existing left foraminal stenosis at L3-L4 and disc herniations at L4-5 did not complain of paresthesia or pain during the combined spinal-epidural anesthetic procedure. However, during epidural analgesia on the second post-operative day, he complained of paresthesia and pain in the anterolateral thigh of the contralateral leg. Electromyography showed a neurogenic lesion at the level of L3. Although an ultrasound-guided diagnostic block of the LFCN was performed twice post-operatively, the patient's symptoms persisted. The symptoms gradually resolved 12 months after the surgery. In our case, we suggest that the continuous epidural infusate caused neural ischemia of the L3 nerve root by a compressive effect. © 2014 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  6. Comparison of efficacy of bupivacaine and fentanyl with bupivacaine and sufentanil for epidural labor analgesia

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    Kalra Sumit

    2010-01-01

    Full Text Available Objectives: A study to compare the efficacy between fentanyl and sufentanil combined with low concentration (0.0625% of bupivacaine for epidural labor analgesia in laboring women. Materials and Methods: Fifty full term parturients received an initial bolus dose of a 10 ml solution containing 0.125% bupivacaine. The patients were randomly divided into two: group F received 0.0625% bupivacaine with 2.5 mcg/ml fentanyl and group S received 0.0625% bupivacaine with 0.25 mcg/ml sufentanil. Verbal analogue pain scores, need of supplementary/rescue boluses dose of bupivacaine consumed, mode of delivery, maternal satisfaction, and neonatal Apgar scores were recorded. No significant difference was observed between both groups. Results: Both the groups provided equivalent labor analgesia and maternal satisfaction. The chances of cesarean delivery were also not increased in any group. No difference in the cephalad extent of sensory analgesia, motor block or neonatal Apgar score were observed. Although mean pain scores throughout the labor and delivery were similar in both groups, more patients in fentanyl group required supplementary boluses though not statistically significant. Conclusion: We conclude that both 0.0625% bupivacaine-fentanyl (2.5 μg/ml and 0.0625% bupivacaine-sufentanil (0.25 μg/ml were equally effective by continuous epidural infusion in providing labor analgesia with hemodynamic stability achieving equivalent maternal satisfaction without serious maternal or fetal side effects. We found that sufentanil was 10 times more potent than fentanyl as an analgesic for continuous epidural labor analgesia.

  7. Effect of epidural analgesia with 0.075% ropivacaine versus 0.1%ropivacaine on the maternal temperature during labor:a randomized controlled study

    Institute of Scientific and Technical Information of China (English)

    YUE Hong-li; SHAO Liu-jiazi; LI Jin; WANG Ya-nan; WANG Lei; HAN Ru-quan

    2013-01-01

    Background A wealth of evidence has indicated that labor epidural analgesia is associated with an increased risk of hyperthermia and overt clinical fever.Recently,evidence is emerging that the epidural analgesia-induced fever is associated with the types of the epidural analgesia and the variations in the epidural analgesia will affect the incidence of fever.The aim of the present study was to investigate the effects of epidural analgesia with 0.075% or 0.1%ropivacaine on the maternal temperature during labor.Methods Two hundred healthy term nulliparas were randomly assigned to receive epidural analgesia with either 0.1% ropivacaine or 0.075% ropivacaine.Epidural analgesia was initiated with 10 ml increment of the randomized solution and 0.5 μg/ml sufentanyl after a negative test dose of 5 ml of 1.5% lidocaine,and maintained with 7 ml bolus doses of the abovementioned mixed analgesics every 30 minutes by the patient-controlled epidural analgesia.The measurements included the maternal oral temperature,visual analog scale pain scores,labor events and neonatal outcomes.Results Epidural analgesia with 0.075% ropivacaine could significantly lower the mean maternal temperature at 4 hours after the initiation of analgesia and the oxytocin administration during labor compared with the one with 0.1%ropivacaine.Moreover,0.075% ropivacaine treatment could provide satisfactory pain relief during labor and had no significant adverse effects on the labor events and neonatal outcomes.Conclusion Epidural analgesia with 0.075% ropivacaine may be a good choice for the epidural analgesia during labor.

  8. Postoperative analgesia in children: A comparison of three different doses of caudal epidural morphine

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    Neha Baduni

    2016-01-01

    Full Text Available Background and Aims: Caudal epidural block is the most commonly used neuraxial block in children. Morphine has been used as a caudal additive for more than three decades. The aim of our study was to evaluate the efficacy and duration of analgesia of three different doses of caudal epidural morphine (CEM, and to find out the incidence of side effects. Material and Methods: This study was conducted on 75 patients of American Society of Anesthesiologists grades I and II, aged 2-12 years, undergoing lower abdominal and urogenital surgeries. Patients were randomly allocated to one of the three groups according to the dose of morphine. Group I received 30 μg/kg, group II 50 μg/kg, and group III 70 μg/kg. Heart rate, blood pressure, oxygen saturation, electrocardiogram, pain score, sedation score, duration of analgesia, and side-effects were noted. Results: The mean duration of analgesia was 8.63 h in group I, 13.36 h in group II and 19.19 h in group III. Respiratory depression was noted in three patients in group III. One patient in group I had itching. One patient each in groups I, II, and III had nausea/vomiting. Conclusion: CEM significantly prolongs the duration of analgesia, though with a higher dose the risk of respiratory depression should always be kept in mind.

  9. PROSPECTIVE RANDOMISED CONTROL STUDY OF POST OP EPIDURAL ANALGESIA WITH BUPIVACAINE AND FENTANYL VS. BUPIVACAINE AND CLONIDINE

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    Rachana

    2014-07-01

    Full Text Available The aim of the study was to compare the relative potencies and clinical characteristics of epidural Clonidine and Fentanyl with Bupivacaine in lower limb and lower abdominal surgeries using patient-controlled analgesia. In a randomised double-blinded study, 60 ASA I or II patients requiring epidural analgesia for post- operative pain relief were allocated to receive either 0.125% Bupivacaine with Clonidine 1µg/kg or 0.125% Bupivacaine with Fentanyl 1µg/kg via a sterile syringe by trained anaesthesiologists. Analgesia was established with 10-15 ml bolus of study solution. There were significant differences in onset time, duration and quality of analgesia, local anaesthetic consumption, between the two groups. We conclude that 0.125% Bupivacaine with Clonidine 1µg/kg group of patients clinically had better quality of analgesia and for a longer duration in comparison with patients receiving 0.125% Bupivacaine with Fentanyl 1µg/kg.

  10. [Combined spinal-epidural analgesia in labour: its effects on delivery outcome].

    Science.gov (United States)

    Singh, Suneet Kaur Sra Charanjit; Yahya, Nurlia; Misiran, Karis; Masdar, Azlina; Nor, Nadia Md; Yee, Lee Choon

    2016-01-01

    Combined spinal-epidural (CSE) has become an increasingly popular alternative to traditional labour epidural due to its rapid onset and reliable analgesia provided. This was a prospective, convenient sampling study to determine the effects of CSE analgesia on labour outcome. One hundred and ten healthy primigravida parturients with a singleton pregnancy of ≥37 weeks gestation and in the active phase of labour were studied. They were enrolled to the CSE (n=55) or Non-CSE (n=55) group based on whether they consented to CSE analgesia. Non-CSE parturients were offered other methods of labour analgesia. The duration of the first and second stage of labour, rate of instrumental vaginal delivery and emergency cesarean section, and Apgar scores were compared. The mean duration of the first and second stage of labour was not significantly different between both groups. Instrumental delivery rates between the groups were not significantly different (CSE group, 11% versus Non-CSE group, 16%). The slightly higher incidence of cesarean section in the CSE group (16% versus 15% in the Non-CSE group) was not statistically significant. Neonatal outcome in terms of Apgar score of less than 7 at 1 and 5min was similar in both groups. There were no significant differences in the duration of labour, rate of instrumental vaginal delivery and emergency cesarean section, and neonatal outcome in parturients who received compared to those who did not receive CSE for labour analgesia. Copyright © 2014 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  11. Combined spinal-epidural analgesia in labour: its effects on delivery outcome.

    Science.gov (United States)

    Singh, Suneet Kaur Sra Charanjit; Yahya, Nurlia; Misiran, Karis; Masdar, Azlina; Nor, Nadia Md; Yee, Lee Choon

    2016-01-01

    Combined spinal-epidural (CSE) has become an increasingly popular alternative to traditional labour epidural due to its rapid onset and reliable analgesia provided. This was a prospective, convenient sampling study to determine the effects of CSE analgesia on labour outcome. One hundred and ten healthy primigravida parturients with a singleton pregnancy of ≥37 weeks gestation and in the active phase of labour were studied. They were enrolled to the CSE (n=55) or Non-CSE (n=55) group based on whether they consented to CSE analgesia. Non-CSE parturients were offered other methods of labour analgesia. The duration of the first and second stage of labour, rate of instrumental vaginal delivery and emergency cesarean section, and Apgar scores were compared. The mean duration of the first and second stage of labour was not significantly different between both groups. Instrumental delivery rates between the groups were not significantly different (CSE group, 11% versus Non-CSE group, 16%). The slightly higher incidence of cesarean section in the CSE group (16% versus 15% in the Non-CSE group) was not statistically significant. Neonatal outcome in terms of Apgar score of less than 7 at 1 and 5min was similar in both groups. There were no significant differences in the duration of labour, rate of instrumental vaginal delivery and emergency cesarean section, and neonatal outcome in parturients who received compared to those who did not receive CSE for labour analgesia. Copyright © 2014 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.

  12. Audit of a ward-based patient-controlled epidural analgesia service in Ireland.

    LENUS (Irish Health Repository)

    Tan, T

    2012-02-01

    BACKGROUND: Ward-based patient-controlled epidural analgesia (PCEA) for postoperative pain control was introduced at our institution in 2006. We audited the efficacy and safety of ward-based PCEA from January 2006 to December 2008. METHOD: Data were collected from 928 patients who received PCEA in general surgical wards for postoperative analgesia using bupivacaine 0.125% with fentanyl 2 mug\\/mL. RESULTS: On the first postoperative day, the median visual analogue pain score was 2 at rest and 4 on activity. Hypotension occurred in 21 (2.2%) patients, excessive motor blockade in 16 (1.7%), high block in 5 (0.5%), nausea in 5 (0.5%) and pruritus in only 1 patient. Excessive sedation occurred in two (0.2%) patients but no intervention was required. There were no serious complications such as epidural abscess, infection or haematoma. CONCLUSION: Effective and safe postoperative analgesia can be provided with PCEA in a general surgical ward without recourse to high-dependency supervision.

  13. Analgesia epidural para el alivio del dolor después del reemplazo de cadera o de rodilla

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    2014-07-01

    Conclusiones de los autores: La analgesia epidural puede ser útil para el alivio del dolor postoperatorio después de reemplazos importantes de articulaciones de los miembros inferiores. Sin embargo, los efectos beneficiosos pueden estar limitados al período postoperatorio temprano (cuatro a seis horas. Una infusión epidural de anestésico local o una mezcla de anestésico-narcótico local puede ser mejor que un narcótico epidural solo. La magnitud del alivio del dolor se debe sopesar contra la frecuencia de eventos adversos. Las pruebas actuales no son suficientes para establecer conclusiones sobre la frecuencia de complicaciones poco frecuentes de la analgesia epidural, la morbilidad o mortalidad postoperatorias, los resultados funcionales o la duración de la estancia hospitalaria.

  14. Caudal epidural analgesia using lidocaine alone or in combination with ketamine in dromedary camels Camelus dromedarius.

    Science.gov (United States)

    Azari, Omid; Molaei, Mohammad M; Ehsani, Amir H

    2014-02-27

    This study was performed to investigate the analgesic effect of lidocaine and a combination of lidocaine and ketamine following epidural administration in dromedary camels. Ten 12-18-month-old camels were randomly divided into two equal groups. In group L, the animals received 2% lidocaine (0.22 mg/kg) and in group LK the animals received a mixture of 10% ketamine (1 mg/kg) and 2% lidocaine (0.22 mg/kg) administered into the first intercoccygeal (Co1-Co2) epidural space while standing. Onset time and duration of caudal analgesia, sedation level and ataxia were recorded after drug administration. Data were analysed by U Mann-Whitney tests and significance was taken as p dromedary camels compared with the effect of administering lidocaine alone.

  15. Thoracic epidural analgesia in a child with multiple traumatic rib fractures.

    Science.gov (United States)

    Keech, Brian M

    2015-12-01

    The morbidity and mortality associated with blunt thoracic trauma are significant and can be multisystem in nature. Of these, pulmonary complications, including ventilatory impairment secondary to pain, have been recognized to be the most consequential. Although several analgesic strategies have emerged, thoracic epidural analgesia (TEA) has arguably demonstrated superior efficacy and is used frequently in adults. Unfortunately, TEA is rarely used in children after blunt thoracic trauma, but may be of considerable benefit. This low rate of use likely reflects one or more of several factors potentially encountered when considering the use of TEA in pediatric chest wall trauma. Among them are (1) uncertainty regarding safety and efficacy; (2) the technical challenges of pediatric thoracic epidural placement, including technique and equipment concerns; and (3) drug selection, dosing, and toxicity. The following case review describes the successful application of TEA in a 4-year-old boy after multiple traumatic rib fractures and associated pneumothorax and pulmonary contusion.

  16. The effect of bupivacaine with fentanyl temperature on initiation and maintenance of labor epidural analgesia: a randomized controlled study.

    Science.gov (United States)

    Sviggum, H P; Yacoubian, S; Liu, X; Tsen, L C

    2015-02-01

    Labor epidural analgesia is highly effective, but can be limited by slow onset and incomplete blockade. The administration of warmed, compared to room temperature, bupivacaine has resulted in more rapid onset epidural anesthesia. We hypothesized that the administration of bupivacaine with fentanyl at 37°C versus 20°C would result in improved initial and ongoing labor epidural analgesia. In this prospective, randomized, doubled blinded study, 54 nulliparous, laboring women were randomized to receive epidural bupivacaine 0.125% with fentanyl 2 μg/mL (20 mL initial and 6 mL hourly boluses) at either 37°C or 20°C. Pain verbal rating scores (VRS), sensory level, oral temperature, and side effects were assessed after epidural loading (time 0), at 5, 10, 15, 20, 30, 60 min, and at hourly intervals. The primary outcome was the time to achieve initial satisfactory analgesia (VRS ⩽3). Secondary outcomes included ongoing quality of sensory blockade, body temperature and shivering. There were no differences between groups in patient demographics, initial pain scores, cervical dilatation, body temperature or mode of delivery. Epidural bupivacaine at 37°C resulted in shorter mean (±SD) analgesic onset time (9.2±4.7 vs. 16.0±10.5 min, P=0.005) and improved analgesia for the first 15 min after initial bolus (P=0.001-0.03). Although patient temperature increased during the study (Plabor analgesia for the first 15 min. There was no evidence of improved ongoing labor analgesia or differences in side effects between groups. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. A comparative study of oral tapentadol with thoracic epidural analgesia versus intravenous tramadol and paracetamol combination for postoperative analgesia in off pump CABG

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    Himanshu A. Shah

    2013-12-01

    Conclusions: Our study concludes that Tapentadol with Thoracic epidural is very much effective as a multimodal analgesia approach in controlling acute postoperative pain after CABG. Tapentadol is quite a newer drug so its usefulness for other patients and different surgeries is still to be debated. [Int J Basic Clin Pharmacol 2013; 2(6.000: 723-727

  18. Epidural analgesia for traumatic rib fractures is associated with worse outcomes: a matched analysis.

    Science.gov (United States)

    McKendy, Katherine M; Lee, Lawrence F; Boulva, Kerianne; Deckelbaum, Dan L; Mulder, David S; Razek, Tarek S; Grushka, Jeremy R

    2017-06-15

    The optimal method of pain control for patients with traumatic rib fractures is unknown. The aim of this study was to determine the effect of epidural analgesia on respiratory complications and in-hospital mortality in patients with rib fractures. Adult patients at a level I trauma center with ≥1 rib fracture from blunt trauma were included (2004-2013). Those with a blunt-penetrating mechanism, traumatic brain injury, or underwent a laparotomy or thoracotomy were excluded. Patients who were treated with epidural analgesia (EPI) were compared with those were not treated with epidural analgesia (NEPI) using coarsened exact matching. Primary outcomes were respiratory complications (pneumonia, deep vein thrombosis/pulmonary embolus, and respiratory failure) and 30-d in-hospital mortality. Secondary outcomes were total hospital and intensive care unit length of stay, and duration of ventilator support. About 1360 patients (EPI: 329 and NEPI: 1031) met inclusion criteria (mean age: 54.2 y; standard deviation [SD]: 19.7; 68% male). The mean number of rib fractures was 4.8 (SD: 3.3; 21% bilateral) with a high total burden of injury (mean Injury Severity Score: 19.9 [SD: 8.9]). The overall incidence of respiratory complications was 13% and mortality was 4%. After matching, 204 EPI patients were compared with 204 NEPI patients, with no differences in baseline characteristics. EPI patients experienced more respiratory complications (19% versus 10%, P = 0.009), but no differences in 30-d mortality (5% versus 2%, P = 0.159), duration of mechanical ventilation (EPI: 148 h [SD: 167] versus NEPI: 117 h [SD: 187], P = 0.434), or duration of intensive care unit length of stay (6.5 d [SD: 7.6] versus 5.8 d [SD: 9.1], P = 0.626). Hospital stay was higher in the EPI group (16.6 d [SD: 19.6] vs 12.7 d [SD: 15.2], P = 0.026). Epidural analgesia is associated with increased respiratory complications without providing mortality benefit after traumatic rib fractures

  19. Comparison of continuous thoracic epidural and paravertebral block for postoperative analgesia after robotic-assisted coronary artery bypass surgery

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    Mehta Yatin

    2008-01-01

    Full Text Available Minimally invasive surgery with robotic assistance should elicit minimal pain. Regional analgesic techniques have shown excellent analgesia after thoracotomy. Thus the aim of this study was to compare thoracic epidural analgesia (TEA technique with paravertebral block (PVB technique in these patients with regard to quality of analgesia, complications, and haemodynamic and respiratory parameters. This was a prospective randomised study involving 36 patients undergoing elective robotic-assisted coronary artery bypass grafting (CABG. TEA or PVB were administered in these patients. The results revealed no significant differences with regard to demographics, haemodynamics, and arterial blood gases. Pulmonary functions were better maintained in PVB group postoperatively; however, this was statistically insignificant. The quality of analgesia was also comparable in both the groups. We conclude that PVB is a safe and effective technique for postoperative analgesia after robotic-assisted CABG and is comparable to TEA with regard to quality of analgesia.

  20. Comparison of Epidural Analgesia with Transversus Abdominis Plane Analgesia for Postoperative Pain Relief in Patients Undergoing Lower Abdominal Surgery: A Prospective Randomized Study

    Science.gov (United States)

    Iyer, Sadasivan Shankar; Bavishi, Harshit; Mohan, Chadalavada Venkataram; Kaur, Navdeep

    2017-01-01

    Background: Anesthesiologists play an important role in postoperative pain management. For analgesia after lower abdominal surgery, epidural analgesia and ultrasound-guided transversus abdominis plane (TAP) block are suitable options. The study aims to compare the analgesic efficacy of both techniques. Materials and Methods: Seventy-two patients undergoing lower abdominal surgery under spinal anesthesia were randomized to postoperatively receive lumbar epidural catheter (Group E) or ultrasound-guided TAP block (Group T) through intravenous cannulas placed bilaterally. Group E received 10 ml 0.125% bupivacaine stat and 10 ml 8th hourly for 48 h. Group T received 20 ml 0.125% bupivacaine bilaterally stat and 20 ml bilaterally 8th hourly for 48 h. Pain at rest and on coughing, total paracetamol and tramadol consumption were recorded. Results: Analgesia at rest was comparable between the groups in the first 16 h. At 24 and 48 h, Group E had significantly better analgesia at rest (P = 0.001 and 0.004 respectively). Patients in Group E had significantly higher number of patients with nil or mild pain on coughing at all times. Paracetamol consumption was comparable in both groups, but tramadol consumption was significantly higher in Group T at the end of 48 h (P = 0.001). Conclusion: For lower abdominal surgeries, analgesia provided by intermittent boluses of 0.125% is comparable for first 16 h between epidural and TAP catheters. However, the quality of analgesia provided by the epidural catheter is superior to that provided by TAP catheters beyond that both at rest and on coughing with reduced opioid consumption. PMID:28928569

  1. Epidural Analgesia Versus Patient-Controlled Analgesia for Pain Relief in Uterine Artery Embolization for Uterine Fibroids: A Decision Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kooij, Sanne M. van der, E-mail: s.m.vanderkooij@amc.uva.nl; Moolenaar, Lobke M.; Ankum, Willem M. [Academic Medical Centre, Department of Gynaecology (Netherlands); Reekers, Jim A. [Academic Medical Centre, Department of Radiology (Netherlands); Mol, Ben Willem J. [Academic Medical Centre, Department of Gynaecology (Netherlands); Hehenkamp, Wouter J. K. [VU University Medical Centre, Department of Gynaecology (Netherlands)

    2013-12-15

    Purpose: This study was designed to compare the costs and effects of epidural analgesia (EDA) to those of patient-controlled intravenous analgesia (PCA) for postintervention pain relief in women having uterine artery embolization (UAE) for systematic uterine fibroids. Methods: Cost-effectiveness analysis (CEA) based on data from the literature by constructing a decision tree to model the clinical pathways for estimating the effects and costs of treatment with EDA and PCA. Literature on EDA for pain-relief after UAE was missing, and therefore, data on EDA for abdominal surgery were used. Outcome measures were compared costs to reduce one point in visual analogue score (VAS) or numeric rating scale (NRS) for pain 6 and 24 h after UAE and risk for complications. Results: Six hours after the intervention, the VAS was 3.56 when using PCA and 2.0 when using EDA. The costs for pain relief in women undergoing UAE with PCA and EDA were Euro-Sign 191 and Euro-Sign 355, respectively. The costs for EDA to reduce the VAS score 6 h after the intervention with one point compared with PCA were Euro-Sign 105 and Euro-Sign 179 after 24 h. The risk of having a complication was 2.45 times higher when using EDA. Conclusions: The results of this indirect comparison of EDA for abdominal surgery with PCA for UAE show that EDA would provide superior analgesia for post UAE pain at 6 and 24 h but with higher costs and an increased risk of complications.

  2. Effects on mother and fetus of epidural and combined spinal-epidural techniques for labor analgesia Efeitos maternos e fetais da analgesia de parto pelas técnicas peridural e duplo bloqueio

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    Giane Nakamura

    2009-01-01

    Full Text Available OBJECTIVE: Epidural (EA and combined spinal-epidural (CSE techniques have both been utilized for labor analgesia. This study compared the effects on the mother and newborn of these techniques in labor analgesia and anesthesia. METHODS: Forty pregnant women received epidural analgesia with 15 mL of 0.125% ropivacaine (EA group and 5 µg of sufentanil plus 2.5mg bupivacaine in the subarachnoid space (CSE group. Pain intensity, sensory blockade level, latency time, motor block intensity, labor analgesia duration, epidural analgesia duration, maternal hypotension, and pruritus were evaluated. The newborns were evaluated by Apgar and the neurological and adaptive capacity score (NACS developed by Amiel-Tison. RESULTS: There were no significant statistical differences between groups for pain scores, latency time, sensory blockade level, and Apgar score. Motor block, labor analgesia duration, and epidural analgesia duration were greater in the CSE group, whose seven mothers had mild pruritus. The NACS were greater in the EA group after half, two, and 24 hours. Ninety five percent of EA group newborns and 60% of CSE group newborns were found to be neurologically healthy at the 24 hour examination. CONCLUSION: EA and CSE analgesia relieved maternal pain during obstetric analgesia, but CSE mothers had pruritus and a longer labor. Newborns of mothers who received epidural analgesia showed the best NACS.OBJETIVO: A peridural (AP e a técnica de duplo bloqueio (DB são utilizadas em analgesia para o trabalho de parto. Este estudo comparou os efeitos na mãe e no feto de ambas as técnicas em analgesia e anestesia para o parto. MÉTODOS: Quarenta parturientes ASA I e II receberam por via peridural 15 ml de ropivacaína a 0,125% (grupo AP e 5 µg de sufentanil com 2,5 mg bupivacaína por via subaracnóidea (grupo DB. Foram avaliados: intensidade de dor, altura do bloqueio sensitivo, tempo de latência, bloqueio motor, duração da analgesia de parto, tempo

  3. Evaluation of the effect of gabapentin on postoperative analgesia with epidural morphine after abdominal hysterectomy

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    Diptesh Aryal

    2017-07-01

    Full Text Available Background & Objectives: Gabapentin has been used successfully as a non-opioid analgesic adjuvant for postoperative pain management. We hypothesized that the preoperative use of gabapentin prolonged the analgesic effect of epidural morphine without an increase in adverse effects of morphine. Materials & Methods: In a randomized, double blind study sixty ASA PS I and II patients undergoing abdominal hysterectomy were assigned to receive either placebo or gabapentin 1200mg 1 hour before surgery. Postoperatively, 0.125% bupivacaine with morphine 50 µg per kg body weight was used for epidural analgesia. Vital parameters, time to the first request for analgesic, visual analogue scale scoring for pain at rest and during movement, 24-hour morphine consumption, and side effects were studied.Results: The patients were comparable with respect to age, weight, ASA PS, baseline hemodynamic parameters and duration of surgery. Gabapentin significantly decreased the duration of analgesia compared to placebo (1078.26 min Vs. 303.5 min; P value <0.0001. The VAS scores at rest and during movement at 1, 2, 4, 8, 12, and 24h were significantly lower in gabapentin group. The total amount of morphine consumption in 24 h postoperatively was significantly lower in gabapentin group (1.93mg Vs. 6.30mg; P value <0.0001. The incidence of nausea and pruritus was significantly lower with gabapentin. Conclusion: Oral gabapentin 1200 mg as a premedication decreases the dose requirement of epidural morphine and postoperative pain after total abdominal hysterectomy. It also decreases the pain scores at rest and during movement significantly. 

  4. [Frequency of colonization and isolated bacteria from the tip of the epidural catheter implanted for postoperative analgesia].

    Science.gov (United States)

    Stabille, Débora Miranda Diogo; Filho, Augusto Diogo; Mandim, Beatriz Lemos da Silva; Araújo, Lúcio Borges de; Mesquita, Priscila Miranda Diogo; Jorge, Miguel Tanús

    2015-01-01

    The increased use of epidural analgesia with catheter leads to the need to demonstrate the safety of this method and know the incidence of catheter colonization, inserted postoperatively for epidural analgesia, and the bacteria responsible for this colonization. From November 2011 to April 2012, patients electively operated and maintained under epidural catheter for postoperative analgesia were evaluated. The catheter tip was collected for semiquantitative and qualitative microbiological analysis. Of 68 cultured catheters, six tips (8.8%) had positive cultures. No patient had superficial or deep infection. The mean duration of catheter use was 43.45hours (18-118) (p=0.0894). The type of surgery (contaminated or uncontaminated), physical status of patients, and surgical time showed no relation with the colonization of catheters. Microorganisms isolated from the catheter tip were Staphylococcus aureus, Pseudomonas aeruginosa and Sphingomonas paucimobilis. Postoperative epidural catheter analgesia, under this study conditions, was found to be low risk for bacterial colonization in patients at surgical wards. Copyright © 2014 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  5. Thoracic epidural analgesia inhibits the neuro-hormonal but not the acute inflammatory stress response after radical retropubic prostatectomy

    NARCIS (Netherlands)

    Fant, F.; Tina, E.; Sandblom, D.; Andersson, S. -O.; Magnuson, A.; Hultgren-Hornkvist, E.; Axelsson, K.; Gupta, A.

    2013-01-01

    Background. Epidural anaesthesia and analgesia has been shown to suppress the neurohormonal stress response, but its role in the inflammatory response is unclear. The primary aim was to assess whether the choice of analgesic technique influences these processes in patients undergoing radical retropu

  6. CLINICAL STUDY OF PATIENT-CONTROLLED EPIDURAL ANALGESIA WITH TETRACAINE HYDROCHLORIDE AFTER PULMONARY LOBECTOMY

    Institute of Scientific and Technical Information of China (English)

    郭向阳; 李勇; 叶铁虎; 任洪智; 黄宇光; 罗爱伦

    2003-01-01

    Objective.To investigate the efficacy and safety of tetracaine hydrochloride in patient-controlled epidural analgesia(PCEA)after pulmonary lobectomy. Methods. Forty-three patients scheduled for elective pulmonary lobectomy under general anesthesia were randomly allocated into either tetracaine group(22 patients)or ropivacaine group(21 patients). In the tetracaine group,0.15% tetracaine was used for postoperative PCEA,while 0.3% ropivacaine was used in the ropiva-caine group. The duration of postoperative analgesia was 48 h. The PCEA included a bolus of 6 ml with a lockout time of 1 h. Postoperative pain score was measured by visual analogue scale(VAS). Forced expired volume at the 1st second(FEV1.0),forced vital capacity(FVC),FEV1.0/ FVC and peak expired flow(PEF)were measured preoperatively and daily after surgery. Hemodynamics were monitored and recorded before and after each administration of local anesthetics during the period of the study. Results. VAS scores in both groups decreased significantly after a bolus injection of local anesthetics. There was no significant difference between the two groups in VAS either before or after the administration of PCEA. On the 1st and 2nd days after the operation,pulmonary function was reduced in both groups. However,there were no significant differences between the percentage of the changes of FEV1.0,FEV1.0/FVC and PEF in the two groups. There were also no significant differences between the percentage of the changes of heart rate,mean arterial blood pressure and SpO2 after administration of local anesthetics. There was no significant difference in overall satisfaction with pain relief.Conclusions. The analgesic effect of 0.15% tetracaine is similar to that of 0.3% ropivacaine used in pa-tient-controlled epidural analgesia after thoracotomy. No serious side effects were observed.

  7. Postoperative epidural analgesia for patients undergoing pectus excavatum corrective surgery: a 10-year retrospective analysis

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    Siddiqui A

    2016-05-01

    Full Text Available Asad Siddiqui,1 Andrew Tse,2 James E Paul,3 Peter Fitzgerald,4 Bernice Teh,51Department of Anesthesia, University of Toronto, Toronto, 2Department of Anesthesia, University of Ottawa, Ottawa, 3Department of Anesthesia, 4Department of Surgery, McMaster University, Hamilton, Ontario, Canada; 5Canterbury Anesthetic Services, Victoria, Australia Introduction: Managing postoperative pain in patients undergoing minimally invasive pectus excavatum repair (Nuss procedure is challenging but essential in facilitating ambulation and minimizing the length of stay. Although multiple epidural regimens with varying opioids are presently used for pain management, there is currently no clinical consensus regarding which epidural regimen provides the best analgesia outcomes with the fewest side effects. This 10-year retrospective cohort study was performed to compare the quality of analgesia and the incidence of side effects associated with the three most common epidural regimens used at a tertiary care children's hospital, in patients undergoing the Nuss procedure. Methods: Seventy-two pediatric patients were identified as having been treated with one of three epidural regimens for postoperative pain management following the Nuss procedure: Group A (n=12 received 0.125% bupivacaine and 5 µg/mL fentanyl, Group B (n=21 received 0.125% bupivacaine and 10 µg/mL hydromorphone, and Group C (n=39 received 0.1% ropivacaine and 20 µg/mL hydromorphone. Our primary outcome was maximal daily pain scores (numerical rating scale 0–10, with an analytical focus on postoperative day 1 scores. The primary outcome was analyzed using linear regression. The secondary outcomes included the length of stay, side-effect profiles as reflected by the number of treatments for nausea and pruritus, pain scores according to epidural site insertion, occurrence of breakthrough pain, and presence of severe pain throughout their hospital stay. Secondary outcomes were analyzed using linear or

  8. A comparison of the postoperative analgesic efficacy between epidural and intravenous analgesia in major spine surgery: a meta-analysis

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    Meng Y

    2017-02-01

    Full Text Available Yichen Meng,* Heng Jiang,* Chenglin Zhang,* Jianquan Zhao, Ce Wang, Rui Gao, Xuhui Zhou Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Postoperative analgesia remains a challenge for orthopedic surgeons. The aim of this meta-analysis is to compare the efficacy of epidural analgesia (EA and intravenous patient-controlled analgesia (IV-PCA following major spine surgery. We searched electronic databases, including the PubMed, EMBASE, Ovid and Cochrane databases, for randomized controlled trials (RCTs published before June 2016. The quality of the included trials was assessed using the Cochrane risk-of-bias tool. Random effects models were used to estimate the standardized mean differences (SMDs and relative risks (RRs, with the corresponding 95% confidence intervals (CI. Subgroup analyses stratified by the type of epidural-infused medication and epidural delivery were also performed. A total of 17 trials matched the inclusion criteria and were chosen for the following meta-analysis. Overall, EA provided significantly superior analgesia, higher patient satisfaction and decreased overall opioid consumption compared with IV-PCA following major spine surgery. Additionally, no differences were found in the side effects associated with these two methods of analgesia. Egger’s and Begg’s tests showed no significant publication bias. We suggest that EA is superior to IV-PCA for pain management after major spine surgery. More large-scale, high-quality trials are needed to verify these findings. Keywords: adolescent idiopathic scoliosis, lumbar fusion, epidural analgesia, intravenous application, perioperative pain

  9. Role of Epidural Analgesia within an ERAS Program after Laparoscopic Colorectal Surgery: A Review and Meta-Analysis of Randomised Controlled Studies

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    Giuseppe Borzellino

    2016-01-01

    Full Text Available Introduction. Epidural analgesia has been a cornerstone of any ERAS program for open colorectal surgery. With the improvements in anesthetic and analgesic techniques as well as the introduction of the laparoscopy for colorectal resection, the role of epidural analgesia has been questioned. The aim of the review was to assess through a meta-analysis the impact of epidural analgesia compared to other analgesic techniques for colorectal laparoscopic surgery within an ERAS program. Methods. Literature research was performed on PubMed, Embase, and the Cochrane Library. All randomised clinical trials that reported data on hospital stay, postoperative complications, and readmissions rates within an ERAS program with and without an epidural analgesia after a colorectal laparoscopic resection were included. Results. Five randomised clinical trials were selected and a total of 168 patients submitted to epidural analgesia were compared to 163 patients treated by an alternative analgesic technique. Pooled data show a longer hospital stay in the epidural group with a mean difference of 1.07 (95% CI 0.06–2.08 without any significant differences in postoperative complications and readmissions rates. Conclusion. Epidural analgesia does not seem to offer any additional clinical benefits to patients undergoing laparoscopic colorectal surgery within an ERAS program.

  10. Postoperative epidural analgesia for patients undergoing pectus excavatum corrective surgery: a 10-year retrospective analysis

    Science.gov (United States)

    Siddiqui, Asad; Tse, Andrew; Paul, James E; Fitzgerald, Peter; Teh, Bernice

    2016-01-01

    Introduction Managing postoperative pain in patients undergoing minimally invasive pectus excavatum repair (Nuss procedure) is challenging but essential in facilitating ambulation and minimizing the length of stay. Although multiple epidural regimens with varying opioids are presently used for pain management, there is currently no clinical consensus regarding which epidural regimen provides the best analgesia outcomes with the fewest side effects. This 10-year retrospective cohort study was performed to compare the quality of analgesia and the incidence of side effects associated with the three most common epidural regimens used at a tertiary care children’s hospital, in patients undergoing the Nuss procedure. Methods Seventy-two pediatric patients were identified as having been treated with one of three epidural regimens for postoperative pain management following the Nuss procedure: Group A (n=12) received 0.125% bupivacaine and 5 µg/mL fentanyl, Group B (n=21) received 0.125% bupivacaine and 10 µg/mL hydromorphone, and Group C (n=39) received 0.1% ropivacaine and 20 µg/mL hydromorphone. Our primary outcome was maximal daily pain scores (numerical rating scale 0–10), with an analytical focus on postoperative day 1 scores. The primary outcome was analyzed using linear regression. The secondary outcomes included the length of stay, side-effect profiles as reflected by the number of treatments for nausea and pruritus, pain scores according to epidural site insertion, occurrence of breakthrough pain, and presence of severe pain throughout their hospital stay. Secondary outcomes were analyzed using linear or logistic regression adjusted for pain scores at baseline. The criterion for statistical significance was set a priori at alpha =0.05. Results Group A had significantly higher day-1 pain scores (score 5.42/10) than Group B (4.52/10; P=0.030) and Group C (4.49/10; P=0.015) after adjusting for baseline pain and age. No significant difference in maximum daily

  11. Posterior Intercostal Nerve Block With Liposomal Bupivacaine: An Alternative to Thoracic Epidural Analgesia.

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    Rice, David C; Cata, Juan P; Mena, Gabriel E; Rodriguez-Restrepo, Andrea; Correa, Arlene M; Mehran, Reza J

    2015-06-01

    Pain relief using regional neuroaxial blockade is standard care for patients undergoing major thoracic surgery. Thoracic epidural analgesia (TEA) provides effective postoperative analgesia but has unwanted side effects, including hypotension, urinary retention, nausea, and vomiting, and is highly operator dependent. Single-shot intercostal nerve and paravertebral blockade have not been widely used because of the short duration of action of most local anesthetics; however, the recent availability of liposomal bupivacaine (LipoB) offers the potential to provide prolonged blockade of intercostal nerves (72 to 96 hours). We hypothesized that a five-level unilateral posterior intercostal nerve block using LipoB would provide effective analgesia for patients undergoing thoracic surgery. We identified patients who underwent lung resection using intraoperative LipoB posterior intercostal nerve blockade and retrospectively compared them with a group of patients who had TEA and who were matched for age, sex, type of surgery, and surgical approach. We analyzed perioperative morbidity, pain scores and narcotic requirements. There were 54 patients in each group. Mean hospital stay was 3.5 days and 4.5 days (p = 0.004) for LipoB group and TEA group, respectively. There were no significant differences in perioperative complications, postoperative pain scores, or in narcotic utilization between LipoB group and TEA group. No acute toxicity related to LipoB was observed. Posterior intercostal nerve blockade using LipoB is safe and provides effective analgesia for patients undergoing thoracic surgery. It may be considered as a suitable alternative to TEA. Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  12. Thermal balance during transurethral resection of the prostate. A comparison of general anaesthesia and epidural analgesia

    DEFF Research Database (Denmark)

    Stjernström, H; Henneberg, S; Eklund, A;

    1985-01-01

    anaesthesia (G.A.) or epidural analgesia (E.A.). Oxygen uptake, catecholamines, peripheral and central temperatures were followed in the per- and postoperative period. Heat production and total body heat were calculated from oxygen uptake and temperature measurements, respectively. Transurethral resection......Heat loss during anaesthesia and surgery is a common problem. In patients with restricted cardio-pulmonary reserves this may endanger the postoperative outcome. In order to compare thermal balance we studied 25 men undergoing transurethral resection of the prostate (TURP), using either general...... of the prostate resulted in a peroperative heat loss which was not influenced by the anaesthetic technique used and averaged 370 kJ during the first hour of surgery. G.A. reduced heat production while this was uninfluenced by E.A. After termination of general anaesthesia, oxygen uptake and plasma catecholamines...

  13. [Comparison of clinical effectiveness of thoracic epidural and intravenous patient-controlled analgesia for the treatment of rib fractures pain in intensive care unit].

    Science.gov (United States)

    Topçu, Ismet; Ekici, Zeynep; Sakarya, Melek

    2007-07-01

    The results of thoracic epidural and systemic patient controlled analgesia practice were evaluated retrospectively in patients with thoracic trauma. Patients who were admitted to the intensive care unit between 1997 and 2003, with a diagnosis of multiple rib fractures related to thoracic trauma were evaluated retrospectively. Data were recorded from 49 patients who met the following criteria; three or more rib fractures, initiation of PCA with I.V. phentanyl or thoracic epidural analgesia with phentanyl and bupivacaine. There were no significant differences between the groups concerning injury severity score. APACHE II score (8.1+/-1.6 and 9.2+/-1.7) and the number of rib fractures (4+/-1.1 and 6.8+/-2.7) were higher in thoracic epidural analgesia group (pPain scores of patients who received thoracic epidural analgesia were significantly lower as from 6th hour during whole therapy (prib fractures who require intensive care.

  14. Analgesic efficacy using loss of resistance to air vs. saline in combined spinal epidural technique for labour analgesia.

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    Leo, S; Lim, Y; Sia, A T H

    2008-09-01

    Identification of the epidural space is often performed using the loss of resistance technique to either air or saline. We sought to investigate if the medium used affected the quality of analgesia obtained by parturients who received labour epidurals. We conducted a retrospective audit of labour epidurals performed on nulliparous parturients in our institution from May 2003 to March 2005. All epidural catheters were inserted by senior obstetric anaesthetists using a combined spinal epidural technique. The following information was recorded: parturients' demographic data, loss of resistance technique used, type and amount of local anaesthetic solution administered, complications encountered during procedure, pre-block and post-block pain scores, incidence of breakthrough pain requiring supplemental medication and post-block side-effects. Data from 2848 patients were collected and analysed; 56% of patients made up the saline group and 44% the air group. Patients in both groups had similar demographic profiles and similar incidences of complications and post-block side-effects. However patients in the air group had a higher incidence of recurrent breakthrough pain P = 0.023). We also identified three other factors that were associated with an increased incidence of recurrent breakthrough pain; administration of pre-block oxytocin, sitting position of the parturient during the procedure and the use of intrathecal bupivacaine for induction of analgesia. Our findings suggest that a loss of resistance to air is associated with a higher incidence of recurrent breakthrough pain among parturients who received combined spinal epidural analgesia for labour than a loss of resistance to saline.

  15. Manipulation with prolonged epidural analgesia for treatment of TKA complicated by arthrofibrosis.

    Science.gov (United States)

    Pariente, Gerardo Mangino; Lombardi, Adolph V; Berend, Keith R; Mallory, Thomas H; Adams, Joanne B

    2006-01-01

    Inability to achieve adequate range of motion (ROM) after total knee arthroplasty (TKA) represents a frustrating complication for both patient and surgeon. Manipulation under anesthesia is indicated in TKA having less than 90 degrees ROM after six weeks, with no progression or regression in ROM. A modified technique has evolved for patients with chronic regional pain syndrome (CRPS) symptoms or persistent stiffness after standard manipulation. A retrospective review was conducted to determine the efficacy of the modified technique, which uses epidural anesthesia continued for postoperative analgesia, hospital stay of one to three days, continuous passive motion (CPM) for two to three days, and daily physical therapy (PT). Between 1997 and 2003, 5714 TKAs were performed in 4106 patients. Manipulation using a standard technique was performed on 334 (5.8%) knees in 273 patients. Manipulation using a modified technique was performed on 65 (1%) knees in 60 patients. Age averaged 58 years and body mass index (BMI) averaged 34.39. Follow up averaged 18.4 months. ROM improved significantly from 71 degrees to 102 degrees (p arthrofibrosis, which included one full revision, five polyethylene exchanges, and three revisions of femoral component and polyethylene. Two significant complications occurred: one subdural hematoma and one death due to pulmonary embolism. Although not without complications, manipulation under epidural anesthesia represents a viable option for treatment of persistent stiffness after TKA; 80% of these difficult cases achieved successful results.

  16. The effects of desflurane and remifentanyl anaesthesia compared to lumbar epidural analgesia combined with desflurane on recovery

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    Celaleddin Soyalp

    2014-12-01

    Full Text Available Objective: Our primary objective in this study is to compare the effects of the applications of desflurane and remifentanyl anaesthesia, along with lumbar epidural analgesia combined with desflurane on postoperative recovery in the cases who undergoing lower abdominal surgery. Methods: This study performed 240 patients who undergoing elective lower abdominal surgery. Patients were divided into two random groups as Group DR (desflurane + remifentanyl n=120 and Group DL (desflurane +Lumbar Epidural Analgesia n=120.The general anaesthesia in Group DR was performed through the use of desflurane and remifentanyl. Group DL was administered a general anaesthesia through a pre-operative epidural catheter insertion and an application of desflurane. Extubation, eye opening, head lift for 5 seconds, and the surgical durations of the patients as well as the postoperative side-effects were recorded. Modified Aldrete Scoring System was used to assess the recovery of the patients from anaesthesia. Results: According to the inter group comparison results between Group DR and Group DL, the duration of extubation, eye opening, head lift for 5 seconds and the average amount of elapsed time until the modified Aldrete Scoring reached 10 were found statistically and significantly shorter in Group DL than Group DR( respectively p=0.002, p<0.001, p<0.001, p<0.001.The duration of the first analgesic need was statistically and significantly longer in Group DL compared to Group DR (p<0.001. The postoperative patient satisfaction in Group DL was statistically and significantly higher than that in Group DR (p=0.010. Conclusion: The Epidural analgesia included in the general anaesthesia in lower abdominal surgery is considered by us to be the beneficial and efficient method of analgesia which leads to an earlier recovery of the patients without affecting the intraoperative hemodynamic stability and which boosts the patient satisfaction by providing a more efficient analgesia

  17. High Thoracic Epidural Analgesia as an Adjunct to General Anesthesia is Associated with Better Outcome in Low-to-Moderate Risk Cardiac Surgery Patients

    DEFF Research Database (Denmark)

    Stenger, Michael; Fabrin, Anja; Schmidt, Henrik

    2013-01-01

    The purpose of this study was to evaluate the addition of high thoracic epidural analgesia (HTEA) to general anesthesia in cardiac surgery patients to enhance the fast-track and improvement in outcome.......The purpose of this study was to evaluate the addition of high thoracic epidural analgesia (HTEA) to general anesthesia in cardiac surgery patients to enhance the fast-track and improvement in outcome....

  18. STUDY OF ULTRASOUND-GUIDED CONTINUOUS FEMORAL NERVE BLOCKADE WITH EPIDURAL ANALGESIA FOR PAIN RELIEF AFTER TOTAL KNEE REPLACEMENT

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    Srinivas Rapolu

    2016-11-01

    Full Text Available BACKGROUND Total knee replacement causes moderate-to-severe pain requiring effective analgesia. With use of ultrasound guidance, we may prove a more suitable approach compared with the epidural technique. Aim of this study is the comparison between Continuous Epidural Analgesia (CEA and Continuous Femoral Block (CFB techniques in Total Knee Replacement surgeries. MATERIALS AND METHODS This study was conducted on 60 adult male and female patients undergoing total knee replacement surgery for a period of 2 years. Patients were divided into 2 groups. Group - 1: Continuous epidural analgesia patients, Group - 2: Continuous femoral blockage patients. All patients were assessed clinically preoperatively and investigated to rule out any systemic disease. RESULTS The mean age of patient in Group - 1 was 66.54 ± 4.98 and in Group - 2 was 66.98 ± 5.02 years. P value was > 0.05, which was not significant. No significant differences in gender is observed between the groups. VAS scores were significantly high (P < 0.05 in the femoral group at 6 h, after which there was a declining trend and scores were essentially similar from 24 h. The use of rescue analgesic was also higher in the femoral group. Analysis of side-effects showed that all the five common sideeffects were twice as common in the epidural group than in the femoral study group. Only one patient in the femoral group had urinary retention when compared with four in the epidural group. The differences were not statistically significant. Muscle power at 48 h, time getting out of the bed and time stay in hospital (days are significant in comparison in 2 groups, range of movement is insignificant in groups. Patient satisfaction score was measured on a scale of 1 - 10. Patients in the Femoral group were slightly more satisfied with a mean ± SD score of 8.1 ± 1.2 when compared with the epidural group 7.3 ± 1.01. CONCLUSION Continuous femoral blockade using US guidance provides equivalent analgesia

  19. Performance of the Angle Labor Pain Questionnaire During Initiation of Epidural Analgesia in Early Active Labor.

    Science.gov (United States)

    Angle, Pamela J; Kurtz Landy, Christine; Djordjevic, Jasmine; Barrett, Jon; Kibbe, Alanna; Sriparamananthan, Saiena; Lee, Yuna; Hamata, Lydia; Zaki, Pearl; Kiss, Alex

    2016-12-01

    The Angle Labor Pain Questionnaire (A-LPQ) is a new, 22-item multidimensional psychometric questionnaire that measures the 5 most important dimensions of women's childbirth pain experiences using 5 subscales: The Enormity of the Pain, Fear/Anxiety, Uterine Contraction Pain, Birthing Pain, and Back Pain/Long Haul. Previous work showed that the A-LPQ has overall good psychometric properties and performance during early active labor in women without pain relief. The current study assessed the tool's sensitivity to change during initiation of labor epidural analgesia with the standardized response mean (SRM, primary outcome). Two versions of the A-LPQ were administered once, in each of 2 test sessions, by the same trained interviewer during early active labor. The sequence of administration was randomized (ie, standard question order version [Test 1] followed by mixed version [Test 2] or vice versa). Test 1 was completed before epidural insertion; Test 2 commenced 20 to 30 minutes after the test dose. Providers assessed/treated pain independently of the study. Sensitivity to change was assessed using SRMs, Cohen's d, and paired t tests. Overall pain intensity was concurrently examined using Numeric Rating Scale and the Verbal Rating Scale (VRS); coping was assessed with the Pain Mastery Scale. Changes in pain were measured with the Patient Global Impression of Change Scale. Internal consistency was assessed with Cronbach's α. Concurrent validity with other tools was assessed using Spearman's rank correlation coefficient. A total of 51 complete datasets were analyzed. Most women reported moderate (63%, 32/51) or severe (18%, 9/51) baseline pain on VRS scores during Test 1; 29% (15/51) reported mild pain, and 6% (3/51) reported moderate pain during Test 2. Approximately 90% (46/51) of women reported much or very much improved pain at the end of testing. Cronbach's α for A-LPQ summary scores was excellent (0.94) and ranged from 0.78 (acceptable) to 0.92 (excellent) for

  20. Effects of postoperative epidural analgesia on recurrence-free and overall survival in patients with nonsmall cell lung cancer.

    Science.gov (United States)

    Cata, Juan P; Gottumukkala, Vijaya; Thakar, Dilip; Keerty, Dinesh; Gebhardt, Rodolfo; Liu, Diane D

    2014-02-01

    To determine whether postoperative epidural analgesia is associated with better recurrence-free survival and overall survival after lung cancer surgery. Retrospective study. Academic hospital. Data of patients with stage 1, stage 2, and stage 3 nonsmall cell lung cancer, who underwent tumor resection surgery, were studied. Patient data were grouped into three different postoperative pain management interventions: intravenous patient-controlled analgesia, patient-controlled epidural analgesia, and their combination. Univariate and multicovariate Cox proportional hazards models were applied to assess the effects of covariates of interest on overall survival and recurrence-free survival. The type of postoperative analgesia used for patients who underwent surgery for nonsmall cell lung cancer did not affect recurrence-free survival or overall survival. However, certain variables, including age ≥ 65 years, male gender, body mass index ≥ 25 kg/m(2), ASA physical status 4, and the need for preoperative blood transfusions, pneumonectomy, and postoperative radiation, were associated with decreased recurrence-free survival and overall survival. The type of postoperative analgesia used after surgery for nonsmall cell lung cancer is not associated with better 2-year or 5-year recurrence-free survival or overall survival rates. © 2013 Elsevier Inc. All rights reserved.

  1. Influencia de la analgesia epidural sobre la incidencia de taquiarritmias en el postoperatorio de la cirugía pulmonar Influence of epidural analgesia on the incidence of tachyarrhythmia during pulmonary surgery postoperative

    Directory of Open Access Journals (Sweden)

    A. Gutiérrez-Guillén

    2004-02-01

    Full Text Available Objetivos: Valorar la influencia del uso de analgesia epidural torácica (AET intra y postoperatoria sobre la presentación de taquiarritmias en el postoperatorio de las resecciones pulmonares. Material y métodos: Se han analizado, de forma retrospectiva, los cursos postoperatorios de 200 pacientes consecutivos intervenidos de resecciones pulmonares mayores (lobectomías, bilobectomías y neumonectomías en nuestro hospital durante el periodo comprendido entre octubre de 1998 y junio de 2002. En este tiempo se ha introducido progresivamente en nuestro Servicio la AET como parte de la técnica anestésica en cirugía pulmonar. Se ha analizado la influencia del empleo de AET en la presentación de episodios de taquiarritmia supraventricular en las primeras 48 horas de postoperatorio. Resultados: Se empleó AET para el manejo anestésico y control del dolor postoperatorio en el 49,5% de los casos (99/200. No existen diferencias significativas entre los grupos de pacientes con y sin AET en cuanto a edad, sexo, riesgo ASA, duración de la intervención y tipo de resecciones practicadas. Presentaron crisis de taquiarritmia el 9,5% de los pacientes (19/200, tratándose, en todos los casos, de fibrilación auricular paroxística. Entre los pacientes que no recibieron AET la tasa de arritmias fue del 13,86% (14/101, mientras que en aquellos en los que se empleó AET como parte de la técnica anestésica y durante el postoperatorio, dicha tasa fue del 5,05% (5/99, siendo dicha diferencia estadísticamente significativa (p=0,034. Conclusiones: El empleo de AET como parte de la técnica anestésica y para el manejo del dolor postoperatorio en cirugía de resección pulmonar parece ejercer un efecto protector en cuanto al desarrollo de fibrilación auricular en el postoperatorio inmediato. Se discuten las posibles causas de este efecto.Objectives: To assess the impact of intra- and post-operative thoracic epidural analgesia (TEA on the incidence of tachy

  2. A CLINICAL COMPARISON OF COMPOUNDED SOLUTION (2% XYLOCAINE & 0.5% BUPIVACAINE WITH 0.5% BUPIVACAINE IN EPIDURAL ANALGESIA

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    Sathesha

    2014-09-01

    Full Text Available Epidural Analgesia is used for relief of pain during and following surgical operations, for relief of chronic pain, for relief of pain in labour, reduction of bleeding by producing sympathetic blockade and hypotension during surgery or to supplement light general anaesthesia, thereby suppressing the transmission of afferent impulses and autonomic and hormonal response to surgery. The commonly used drugs for epidural analgesia are 2% xylocaine and 0.5% bupivacaine. Mixing of the local anaesthetics and altering the pH have been found to be safe and cost effective.1,2 our study was a prospective randomized controlled double blind study to investigate effect of the benefits of usage of a compounded solution (2% xylocaine and 0.5% bupivacaine in a 1:1 ratio over a single drug (0.5% bupivacaine and ascertain whether it can be recommended for routine use in epidural analgesia in regular anaesthetic practice.3,4,5 The following parameters are Studied 1 The time of onset of analgesia. 2 The quality of analgesia. 3 The degree of motor blockade. 4 Duration of analgesia. 5 Safety of compounding local anaesthetics. METHODS AND MATERIAL: One Hundred Adult Patients of either sex ranging between 20-60 years of age belonging to ASA grade 1 and II were studied. All patients were at random divided into 2 groups fifty in each group. Group A received 0.5% bupivacaine 15cc. Group B received a mixture of 0.5% bupivacine and 2% xylocaine (7.5cc + 7.5cc RESULTS: Mean time of onset of analgesia in group B was lower (11.50 + 2.05 as compared to group A (22.24 + 2.18 and this difference was statistically highly significant (P<0.001. 16% of group A and 6% of group B required to be changed over to general anaesthesia. Grade IV motor blockade was seen only in 24% of group A and 30% of the group B which is significant. Mean duration of action in group A was higher (128.90 + 6.70 than in group B (98.30 + 5.29 and this difference was statistically significant. CONCLUSIONS: The

  3. [Pressure Ulcer Caused by Long-term Keeping of the Same Body Position during Epidural Labour Analgesia].

    Science.gov (United States)

    Naruse, Satoshi; Uchizaki, Sakiko; Mimura, Shinichiro; Taniguchi, Mizuki; Akinaga, Chieko; Sato, Shigehito

    2016-06-01

    We report the case of a 34-year-old woman (height: 153 cm, weight : 62.4 kg, non-pregnant weight : 52 kg, uniparous) without underlying diseases who developed pressure ulcer due to keeping a similar body position during long-term epidural delivery. Induction of childbirth was started in gestational week 40, causing reduction of fetal heart rate, which improved after adoption of a right lateral recumbent position. Severe contractions occurred and epidural labour analgesia was started. The fetal heart rate decreased again and induction of childbirth was suspended, but the right lateral recumbent position was maintained. Epidural administration was continued due to persistent contractions. Next morning, induction of childbirth was restarted and birth occurred in approximately 6 hours. The right lateral recumbent position was maintained for approximately 20 hours. At childbirth, a pressure ulcer was present in the intertrochanteric part of the right femur. The causes included insufficient knowledge of medical staff about the risk of pressure ulcer during epidural delivery, and no position change. A decreased sensation and blocked motor nerve caused by epidural anesthesia might have accelerated pressure ulcer development. This case suggests that preventive measures against pressure ulcer are required in epidural anesthesia in pregnant women.

  4. Comparison of Epidural Butorphanol with Neostigmine and Epidural Sufentanyl with Neostigmine for First Stage of Labor Analgesia: A Randomized Controlled Trial

    Science.gov (United States)

    Chaurasia, Manoj; Saxena, Ashok Kumar; Chilkoti, Geetanjali T.

    2017-01-01

    Background: Epidural administration of neostigmine appears to be safe in the obstetric population. Recently, few studies have concluded 10 μg sufentanil to be an effective adjuvant with epidural neostigmine in providing labor analgesia. However, no study has evaluated the analgesic effect of epidural butorphanol with neostigmine for the same. Materials and Methods: The parturients were randomly allocated to one of the three study groups - Group A (n = 30) received butorphanol 1 mg and neostigmine 7 μg/kg. Group B (n = 30) received sufentanil 10 μg and neostigmine 7 μg/kg. Group C (n = 30) received neostigmine 7 μg/kg and 0.9% normal saline. Maternal hemodynamic parameters and fetal heart rate (FHR) were continuously monitored. The level of sensory and motor block, and visual analog scale (VAS) pain score were recorded at designated time points. In addition, the total duration of analgesia, duration of labor, mode of delivery, and any maternal or fetal adverse effects were also recorded. Statistical Analysis Used: A one-way analysis of variance (ANOVA) with post hoc Tukey's test was used to compare mean value among the three groups for age, height, weight, gestational age, and cervical dilatation. Repeated measure ANOVA was used to compare mean difference among the time points and also the trend among the various time points for hemodynamic parameters, VAS pain score, and FHR. For inter-group comparison among the groups, post hoc Tukey test was used. Results: There was a statistically significant longer effect of analgesic drug in Group B with respect to Group A and C (P labor (VAS labor and mode of delivery in-between the two groups, and none of the patients in any group had any maternal or fetal side effects. Conclusion: Epidural combination of sufentanil with neostigmine provided better pain relief in terms of the total duration of analgesia and the reduction in VAS pain scores at various time points in the initial 30 min of epidural administration of drugs

  5. A comparison of intrathecal dexmedetomidine verses intrathecal fentanyl with epidural bupivacaine for combined spinal epidural labor analgesia

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    P K Dilesh

    2014-01-01

    Conclusion: 10 μg dexmedetomidine intrathecally provides a longer duration of analgesia with lesser incidence of pruritus compared to 20 μg fentanyl intrathecally for CSE labor analgesia with comparable neonatal side-effects.

  6. Investigation of the Effects of Continuous Low-Dose Epidural Analgesia on the Autonomic Nervous System Using Hilbert Huang Transform

    Directory of Open Access Journals (Sweden)

    Wei-Ren Chuang

    2010-01-01

    Full Text Available Effects of continuous low-dose epidural bupivacaine (0.05-0.1% infusion on the Doppler velocimetry for labor analgesia have been well documented. The aim of this study was to monitor the activity of the autonomic nervous system (ANS for women in labor based on Hilbert Huang transform (HHT, which performs signal processing for nonlinear systems, such as human cardiac systems. Thirteen pregnant women were included in the experimental group for labor analgesia. They received continuous epidural bupivacaine 0.075% infusion. The normal-to-normal intervals (NN-interval were downloaded from an ECG holter. Another 20 pregnant women in non-anesthesia labor (average gestation age was 38.6 weeks were included in the comparison group. In this study, HHT was used to decompose components of ECG signals, which reflect three different frequency bands of a person's heart rate spectrum (viz. high frequency (HF, low frequency (LF and very low frequency (VLF. It was found that the change of energy in subjects without anesthesia was more active than that with continuous epidural bupivacaine 0.075% infusion. The energy values of the experimental group (i.e., labor analgesia of HF and LF of ANS activities were significantly lower (P < 0.05 than the values of the comparison group (viz. labor without analgesia, but the trend of energy ratio of LF/HF was opposite. In conclusion, the sympathetic and parasympathetic components of ANS are all suppressed by continuous low-dose epidural bupivacaine 0.075% infusion, but parasympathetic power is suppressed more than sympathetic power.

  7. Effects of labor analgesia on maternal and neonatal outcome by epidural low concentration of bupivacaine combined with anisodamine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Objective To observe the effects of labor analgesia on maternal and neonatal outcome by epidural application of 0.125% bupivacaine combined with anisodamine on the labor stage, and modes of delivery and neonatal Apgar's score. Methods A total of 220 primiparaes with full-term pregnancy, monocyesis and fetal head presentation without any obstetrical or systematic complications were chosen and divided into analgesic group and control group (110 in each group). The mixture of bupivacaine and anisodamine was in...

  8. Remifentanilo vs. analgesia epidural para el manejo del dolor agudo relacionado con el trabajo de parto. Revisión sistemática y meta-análisis

    National Research Council Canada - National Science Library

    González Cárdenas, Víctor Hugo; Munar González, Fredy Danilo; Gómez Barajas, Wilson Javier; Cardona, Angélica María; Rosero, Byron Rafael; Manrique, Álvaro José

    2014-01-01

    ... masivo, con similares beneficios y satisfaccion que la analgesia epidural. Metodos: Revision sistematica y meta-analisis de experimentos clinicos siguiendo la metodologia Cochrane. Palabras clave...

  9. Comparison of bupivacaine, ropivacaine and levobupivacaine with sufentanil for patient-controlled epidural analgesia during labor: a randomized clinical trial

    Institute of Scientific and Technical Information of China (English)

    WANG Li-zhong; CHANG Xiang-yang; LIU Xia; HU Xiao-xia; TANG Bei-lei

    2010-01-01

    Background Ropivacaine and levobupivacaine have been introduced into obstetric analgesic practice with the proposed advantages of causing less motor block and toxicity compared with bupivacaine. However, it is still controversial whether both anesthetics are associated with any clinical benefit relative to bupivacaine for labor analgesia. This study aimed to compare the analgesic efficacy, motor block and side effects of bupivacaine, ropivacaine and levobupivacaine at lower concentrations for patient-controlled epidural labor analgesia. Methods Four hundred and fifty nulliparous parturients were enrolled in this randomized clinical trial. A concentration of 0.05%, 0.075%, 0.1%, 0.125% or 0.15% of either bupivacaine (Group B), ropivacaine (Group R) or levobupivacaine (Group L) with sufentanil 0.5 μg/ml was epidurally administered by patient-controlled analgesia mode. Effective analgesia was defined as a visual analogue scale score was ≤30 mm. The relative median potency for each local anesthetic was calculated using a probit regression model. Parturients demographics, sensory and motor blockade, obstetric data, maternal side effects, hourly volumes of local anesthetic used, and others were also noted. Results There were no significant differences among groups in the numbers of effective analgesia, pain scores, hourly local anesthetic amount used, sensory and motor blockade, labor duration and mode of delivery, side effects and maternal satisfaction (P >0.05). The relative median potency was bupivacaine/ropivacaine: 0.828 (0.602-1.091), bupivacaine/levobupivacaine: 0.845 (0.617-1.12), ropivacaine/levobupivacaine: 1.021 (0.774-1.354), respectively. However, a significantly less number of effective analgesia and higher hourly local anesthetic use were observed in the concentration of 0.05% than those of ≥0.1% within each group (P<0.05). Conclusions Using patient-controlled epidural analgesia, lower concentrations of bupivacaine, ropivacaine and levobupivacaine

  10. Analysis and evaluation of the effectiveness of epidural analgesia and its relationship with eutocic or dystocic delivery.

    Science.gov (United States)

    Sánchez-Migallón, V; Sánchez, E; Raynard, M; Miranda, A; Borràs, R M

    Numerous studies have demonstrated the difference in the verbal rating scale with regard to obstructed labour and induced labour, so that obstructed labour and foetal macrosomia have been related to a greater sensation of pain during labour, particularly in the first stage. Even the epidural analgesia is linked to the need for instrumented or caesarean section due to foetal obstruction. The goal of the study is to analyze and evaluate the effectiveness of epidural analgesia in normal versus obstructed labour. One hundred and eighty pregnant women were included in an observational, analytical, longitudinal and prospective study, that was performed in the Obstetrics Department of the Hospital Universitario Dexeus. All the nulliparous or multiparous over 36 weeks of pregnancy, after 3cm of cervical dilatation in spontaneous or induced labor were included. All the patients were given epidural analgesia according to protocol. The basic descriptive methods were used for the univariate statistical analysis of the sample and the Mann-Whitney U test was used for the comparison of means between both groups. The correlations between variables were studied by means of the Spearman coefficient of correlation. The differences regarded as statistically significant are those whose P.05). Copyright © 2016 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  11. Single dose oral clonidine premedication does not enhance postoperative, single low dose epidural morphine analgesia in hysterectomy patients.

    Science.gov (United States)

    Oofuvong, Maliwan; Chanvej, Laksamee; Thongsuksai, Paramee

    2005-03-01

    In this randomized, double blind placebo controlled study, the authors evaluated the effects of oral clonidine premedication on very low dose epidural morphine analgesia in 50 hysterectomy patients. Patients were randomized to receive a single oral clonidine 300 microg (n = 25) or a placebo (n = 25) 90 minutes before insertion of the epidural catheter. 3 ml of 2% lidocaine with adrenaline (5 microg ml(-1) mixed with 2 mg morphine were injected via epidural, followed by an additional volume of 2% lidocaine with adrenaline (5 microg ml(-1)) titrated to T6 block height before commencing general anesthesia. The postoperative analgesia regimen was 2 mg of intravenous morphine every 10 minutes for the first 48 hr and 1 gm of oral acetaminophen every 4-6 hr after initiation of oral diet at 24-48 hr as required. Morphine consumption, acetaminophen, pain scores, and side effects were recorded thoughout 48 hr after surgery. The results show patients in the clonidine and placebo groups were not different in terms of local anesthetics dose (p = 0.27), total morphine and acetaminophen requirement (p = 0.34, p = 0.1) respectively. Pain scores at rest and movement were also not different in both groups (p = 0.83, p = 0.64) respectively. No serious adverse effects were noted. The authors concluded that oral clonidine approximately 6 microg kg(-1) does not enhance the analgesic effect of epidural morphine 2 mg after hysterectomy.

  12. Clinical evaluation of postoperative analgesia provided by ketoprofen associated with intravenous or epidural morphine in bitches undergoing ovariosalpingohysterectomy

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    Gabriela Carvalho Aquilino Santos

    2015-04-01

    Full Text Available Multimodal analgesia refers to the practice of combining multiple analgesic drug classes or techniques to target different points along the pain pathway. The objective of this work was to evaluate clinically if ketoprofen associated or not with intravenous or epidural morphine provided adequate postoperative analgesia in bitches undergoing ovariosalpingohysterectomy (OSH. Forty healthy female dogs, weighing 10.7±6.0 kg, sedated with acepromazine (0.05mg kg –1.iv, induced with propofol (5 mg.kg-1. iv and maintained with isoflurane anesthesia, were distributed into four groups of 10 animals each. After stabilization of inhalation anesthesia, the bitches in Miv and CMiv groups received 0.2 mg.kg-1 of morphine intravenously diluted in 10ml of saline; whereas Mep and CMep groups received 0.1mg.kg-1 of epidural morphine. Thirty minutes after premedication, 2.0mg.kg-1.im of ketoprofen was administered in groups CMiv and CMep. Heart and respiratory rate, systolic blood pressure, and rectal temperature were measured. The degree of analgesia was assessed by a blind study in the following 6 hours after surgery, using a descriptive scale and a scale composed by physiologic and behavioral parameters. An statistical analysis was performed using the Tukey-Kramer test and nonparametric Kruskal-Wallis test, with statistical significance of 5%. There was no important difference between the four groups regarding postoperative analgesia, heart and respiratory rate, systolic blood pressure and rectal temperature. According to the results it can be concluded that the use of ketoprofen associated with intravenous or epidural morphine provided adequate and safe analgesia in the first six hours of postoperative in bitches undergoing ovariohysterectomy, suggesting that there was no analgesic potentiation when both agents were combined.

  13. Resultados obstetricos y perinatales en pacientes con o sin analgesia obstetrica durante el trabajo de parto.(Medical condition overview)

    National Research Council Canada - National Science Library

    Piedrahita-Gutierrez, Dany Leandro; Espana-Chamorro, Jhoana Andrea; Piedrahita-Gutierrez, Wilmar Eduardo; Lopez- Clavijo, Carlos Alberto; Henao-Florez, Rodrigo Eduardo

    2016-01-01

    Objetivo: describir y comparar los resultados obstetricos y perinatales en las pacientes que recibieron analgesia obstetrica durante el trabajo de parto con los de quienes no la recibieron y determinar si...

  14. ¿Se debe mantener la analgesia epidural como técnica de base en la UDA? Should epidural analgesia still be a routine technique in pain units?

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    F. Caba

    2010-05-01

    Full Text Available La analgesia epidural se ha convertido en una técnica rutinaria en el manejo perioperatorio de los pacientes quirúrgicos que se ha extendido fuera de los quirófanos y de las unidades de alta dependencia hacia las salas de hospitalización. La irrupción en este nuevo escenario ha mejorado la analgesia postoperatoria con aceptables márgenes de seguridad, lo que le ha servido para colocarse en un lugar predominante entre las pautas analgésicas de las Unidades de Dolor Agudo (UDA. La analgesia epidural con anestésicos locales y opioides frente a la sistémica con opioides ha presentado históricamente una superior eficacia analgésica, y una disminución de complicaciones derivadas de la atenuación del estrés quirúrgico y de la mejora en la función cardiorrespiratoria. Sin embargo, frente a estas ventajas la analgesia epidural también presenta inconvenientes como la hipotensión arterial o la retención urinaria, junto a las potencialmente graves derivadas del daño neurológico ocasionado por un hematoma epidural, una infección o una lesión directa del tejido nervioso. Si sus ventajas han resultado consistentes y fundamentadas, en este momento no lo parecen tanto. El avance que ha supuesto la cirugía mínimamente invasiva con altas más precoces, junto al desarrollo de estrategias multimodales, está conduciendo a un replanteamiento de la utilización de técnicas como la epidural y a una reevaluación de sus indicaciones. Las últimas evidencias nos inducen a pensar que la epidural probablemente haya tocado techo en el tratamiento del dolor postoperatorio y comenzará a perder terreno frente a otras técnicas igualmente efectivas, con menores complicaciones y efectos secundarios. Este será un proceso lento en el que deberá quedar asegurado que las alternativas analgésicas ofrecen realmente mejores resultados en cuanto a eficacia, seguridad, tolerabilidad y calidad de la recuperación desde la perspectiva del paciente.Epidural

  15. RANDOMISED CONTROLLED STUDY COMPARING A 0.75% ROPIVACAINE TO A CONVENTIONAL DOSE OF HYPERBARIC BUPIVACAINE FOR CESARIAN SECTION BY EPIDURAL ANALGESIA

    Directory of Open Access Journals (Sweden)

    Porika

    2015-09-01

    Full Text Available Central neuraxial blocked is one of the safest and efficacious methods of anaesthesia and analgesia. It has the added advantage of prolonged pain relief into the postoperative period. Epidural analgesia has increased steadily in popularity when compared to spinal anaesthes ia due to its neurological consequences and improved post - operative analgesia with epidural Opioids and as a consequence decreased side effects and prolonged the duration of analgesia. Present study is undertaken to compare hemodynamic and analgesic charac teristics using a 0.75% ropivacaine to a conventional dose of 0.5% bupivacaine for cesarean section under epidural anaesthesia. This study was conducted in ASA Grade I 50 singleton parturient to compare hemodynamics, APGAR scores and analgesic characterist ics of ropivacaine and bupivacaine. We have observed that the onset of sensory blockade was slower with ropivacaine and the duration of sensory blockade was also less. Whereas there was no significant change in haemodynamics and APGAR scores with both the drugs.

  16. Analgesia peridural para o trabalho de parto e para o parto: efeitos da adição de um opióide Effects of the association of an opioid with epidural analgesia for labor and delivery

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    José Guilherme Cecatti

    1998-07-01

    Full Text Available O objetivo deste estudo foi avaliar a eficácia e segurança da associação bupivacaína com sufentanil para a analgesia no trabalho de parto e do parto por meio de um bloqueio peridural contínuo. Realizou-se um ensaio clínico duplo-cego, prospectivo e aleatório, incluindo sessenta mulheres nulíparas da Maternidade do CAISM/UNICAMP. No momento da analgesia, as mulheres foram aleatoriamente alocadas em dois grupos: BS, recebendo 12,5 mg de bupivacaína com adrenalina mais 30 µg de sufentanil e BP, recebendo 12,5 mg de bupivacaína com adrenalina mais placebo. Foram avaliados os parâmetros relativos à qualidade e duração da analgesia, duração do trabalho de parto e também possíveis efeitos sobre o recém-nascido. Os resultados mostraram a superioridade da adição do sufentanil sobre o grau de analgesia durante o tempo de ação da primeira dose de anestésico local. Não houve aumento na duração do trabalho de parto depois do início da analgesia quando se compararam ambos os grupos, nem qualquer diferença quanto à via de parto. Não houve também diferenças entre os grupos com relação à avaliação dos recém-nascidos. Conclui-se que a associação de 30 µg de sufentanil à primeira dose de bupivacaína é segura e eficaz, melhorando a qualidade da analgesia, sua duração e não afetando a progressão do trabalho de parto e o resultado neonatal.The purpose of the present study was to evaluate the efficacy and safety of the association bupivacaine with sufentanil for labor and delivery analgesia through a continuous epidural blockade, for both mother and the neonate. A randomized double blind prospective clinical trial was performed including sixty nulliparous women at the Maternity of CAISM/UNICAMP. When requesting analgesia, the women were randomly allocated to two groups: BS, receiving 12.5 mg of bupivacaine with adrenaline plus 30 µg of sufentanil and BP, receiving 12.5 mg of bupivacaine with adrenaline plus placebo

  17. ¿Se debe mantener la analgesia epidural como técnica de base en la UDA?

    Directory of Open Access Journals (Sweden)

    F. Caba

    2010-05-01

    Full Text Available La analgesia epidural se ha convertido en una técnica rutinaria en el manejo perioperatorio de los pacientes quirúrgicos que se ha extendido fuera de los quirófanos y de las unidades de alta dependencia hacia las salas de hospitalización. La irrupción en este nuevo escenario ha mejorado la analgesia postoperatoria con aceptables márgenes de seguridad, lo que le ha servido para colocarse en un lugar predominante entre las pautas analgésicas de las Unidades de Dolor Agudo (UDA. La analgesia epidural con anestésicos locales y opioides frente a la sistémica con opioides ha presentado históricamente una superior eficacia analgésica, y una disminución de complicaciones derivadas de la atenuación del estrés quirúrgico y de la mejora en la función cardiorrespiratoria. Sin embargo, frente a estas ventajas la analgesia epidural también presenta inconvenientes como la hipotensión arterial o la retención urinaria, junto a las potencialmente graves derivadas del daño neurológico ocasionado por un hematoma epidural, una infección o una lesión directa del tejido nervioso. Si sus ventajas han resultado consistentes y fundamentadas, en este momento no lo parecen tanto. El avance que ha supuesto la cirugía mínimamente invasiva con altas más precoces, junto al desarrollo de estrategias multimodales, está conduciendo a un replanteamiento de la utilización de técnicas como la epidural y a una reevaluación de sus indicaciones. Las últimas evidencias nos inducen a pensar que la epidural probablemente haya tocado techo en el tratamiento del dolor postoperatorio y comenzará a perder terreno frente a otras técnicas igualmente efectivas, con menores complicaciones y efectos secundarios. Este será un proceso lento en el que deberá quedar asegurado que las alternativas analgésicas ofrecen realmente mejores resultados en cuanto a eficacia, seguridad, tolerabilidad y calidad de la recuperación desde la perspectiva del paciente.

  18. Fast Track Liver Resection: The Effect of a Comprehensive Care Package and Analgesia with Single Dose Intrathecal Morphine with Gabapentin or Continuous Epidural Analgesia

    Directory of Open Access Journals (Sweden)

    Jonathan B. Koea

    2009-01-01

    Full Text Available Background. A comprehensive care package for patients undergoing hepatectomy was developed with the aim of minimal physiological disturbance in the peri-operative period. Peri-operative analgesia with few gastrointestinal effects and reduced requirement for intravenous (IV fluid therapy was central to this plan. Methods. Data on 100 consecutive patients managed with continuous epidural infusion (n = 50; bupivicaine 0.125% and fentanyl 2 g/mL at 0.1 mL/kg/hr or intrathecal morphine (n = 50; 300 g in combination with oral gabapentin 1200 mg preoperatively and 400 mg bd postoperatively was compared. Results. The epidural and intrathecal morphine groups were equivalent in terms of patient demographics, procedures and complications. Patients receiving intrathecal morphine received less intra-operative IV fluids (median 1500 mL versus 2200 mL, =.06, less postoperative IV fluids (median 1200 mL versus 4300 mL, =.03 than patients receiving epidural infusion. Patients managed with intrathecal morphine established a normal dietary intake sooner (16 hours versus 20 hours, =.05 and had shorter hospital stays than those managed with epidural infusions (4.7 ± 0.9 days versus 6.8 ± 1.2 days, =.02. Conclusions. Single dose intrathecal morphine is a safe and effective means of providing peri-operative analgesia. Patients managed with intrathecal morphine have reduced peri-operative physiological disturbance and return home within a few days of hepatic resection.

  19. A comparative study of efficacy of epidural versus interpleural bupivacaine for post operative analgesia after open cholecystectomy

    Directory of Open Access Journals (Sweden)

    RK Yadav

    2014-04-01

    Full Text Available Background The conventional methods of administering the prescribed doses of intramuscular or intravenous analgesics at fixed time intervals results in widely fluctuating and inadequate plasma level leads to poor post operative pain relief. Despite all advances made in the field of medicine, this symptom called “Pain” has not been combated well. Objective The present study was carried out to compare the efficacy of epidural verses interpleural administration of bupivacaine(0.5% with adrenaline for post operative pain relieve in patients undergoing open cholecystectomy. Methods We prospectively randomized and compared the post operative pain relieve with the reference of visual analog score (VAS in patients undergoing elective open cholecystectomy in college of medical sciences-teaching hospital, Bharatpur, Chitwan. Forty adult patients undergoing elective cholecystectomy were divided into two groups. Twenty patients in each group were subjected to a different technique of post-operative analgesia, namely thoracic epidural and interpleural instillation of 0.5% bupivacaine. These two groups were then compared in relation to changes produced in the pain scores, vital parameters and complication and side effects associated with the two techniques. The study was conducted for 24 hour postoperatively. Observation: Both thoracic epidural and interpleural instillation of 0.5% bupivacaine compared favorably with regard to analgesia in the present study. In general, the pain relief following thoracic epidural was more complete compared to interpleural but this was not clinically significant. Conclusion The present study shows that both the techniques are equally effective in providing analgesia following cholecystectomy. However, neither technique rendered the patients completely pain free at all times during first 24 hours. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-4, 15-23 DOI: http://dx.doi.org/10.3126/jcmsn.v9i4.10232

  20. Effectiveness of epidural versus alternate analgesia for pain relief after radical prostatectomy and correlation with biochemical recurrence in men with prostate cancer

    Directory of Open Access Journals (Sweden)

    Mir MC

    2013-10-01

    differences were statistically significant (P = 0.012.Conclusion: Epidural analgesia increased length of hospital stay and technical problems related to the epidural. Furthermore, men receiving an epidural showed an increased recurrence of PSA. In light of our findings, epidurals are probably not indicated for men undergoing RRP. However, as minimally invasive techniques are becoming more widespread, and epidural analgesia is being used less frequently, large randomized controlled trials to definitively support our hypotheses are unlikely to be undertaken.Keywords: prostate neoplasm, surgery, prostatectomy, analgesia, epidural

  1. Thoracic epidural analgesia: a new approach for the treatment of acute pancreatitis?

    Science.gov (United States)

    Windisch, Olivier; Heidegger, Claudia-Paula; Giraud, Raphaël; Morel, Philippe; Bühler, Léo

    2016-05-04

    This review article analyzes, through a nonsystematic approach, the pathophysiology of acute pancreatitis (AP) with a focus on the effects of thoracic epidural analgesia (TEA) on the disease. The benefit-risk balance is also discussed. AP has an overall mortality of 1 %, increasing to 30 % in its severe form. The systemic inflammation induces a strong activation of the sympathetic system, with a decrease in the blood flow supply to the gastrointestinal system that can lead to the development of pancreatic necrosis. The current treatment for severe AP is symptomatic and tries to correct the systemic inflammatory response syndrome or the multiorgan dysfunction. Besides the removal of gallstones in biliary pancreatitis, no satisfactory causal treatment exists. TEA is widely used, mainly for its analgesic effect. TEA also induces a targeted sympathectomy in the anesthetized region, which results in splanchnic vasodilatation and an improvement in local microcirculation. Increasing evidence shows benefits of TEA in animal AP: improved splanchnic and pancreatic perfusion, improved pancreatic microcirculation, reduced liver damage, and significantly reduced mortality. Until now, only few clinical studies have been performed on the use of TEA during AP with few available data regarding the effect of TEA on the splanchnic perfusion. Increasing evidence suggests that TEA is a safe procedure and could appear as a new treatment approach for human AP, based on the significant benefits observed in animal studies and safety of use for human. Further clinical studies are required to confirm the clinical benefits observed in animal studies.

  2. Predicting postoperative vomiting among orthopedic patients receiving patient-controlled epidural analgesia using SVM and LR.

    Science.gov (United States)

    Wu, Hsin-Yun; Gong, Cihun-Siyong Alex; Lin, Shih-Pin; Chang, Kuang-Yi; Tsou, Mei-Yung; Ting, Chien-Kun

    2016-06-01

    Patient-controlled epidural analgesia (PCEA) has been applied to reduce postoperative pain in orthopedic surgical patients. Unfortunately, PCEA is occasionally accompanied by nausea and vomiting. The logistic regression (LR) model is widely used to predict vomiting, and recently support vector machines (SVM), a supervised machine learning method, has been used for classification and prediction. Unlike our previous work which compared Artificial Neural Networks (ANNs) with LR, this study uses a SVM-based predictive model to identify patients with high risk of vomiting during PCEA and comparing results with those derived from the LR-based model. From January to March 2007, data from 195 patients undergoing PCEA following orthopedic surgery were applied to develop two predictive models. 75% of the data were randomly selected for training, while the remainder was used for testing to validate predictive performance. The area under curve (AUC) was measured using the Receiver Operating Characteristic curve (ROC). The area under ROC curves of LR and SVM models were 0.734 and 0.929, respectively. A computer-based predictive model can be used to identify those who are at high risk for vomiting after PCEA, allowing for patient-specific therapeutic intervention or the use of alternative analgesic methods.

  3. [Combined epidural-spinal analgesia during labor: a quantitative systematic review of the literature (meta-analysis)].

    Science.gov (United States)

    Pascual-Ramírez, J; Haya Palazuelo, J; Valverde Mantecón, J M

    2013-11-01

    To perform a meta-analysis on the use of combined epidural-intrathecal analgesia during labor, including intrathecal fentanyl and/or morphine compared to usual epidural techniques. A literature search was made looking for randomized clinical trials in MEDLINE, EMBASE and Cochrane Library. The size of the effect for quantitative variables was analyzed by weighted mean difference; for qualitative variables, by odds ratio. Variables analyzed were: labor duration, type of delivery (spontaneous, instrumental and caesarean section), motor blockade, pain, and satisfaction. The analysis used in most cases was a random effects model. A total of 21 trials, which included 3.646 patients, were selected out of the 38 initially found. The type of delivery variable with its 3 subgroups was the only one to show uniformity (p>Q 0.1; I(2)<50%). There were no differences in the variables analyzed except pain, which was advantageous for the group with intrathecal fentanyl or morphine by 0.55 points out of 10. Combined analgesia including intrathecal fentanyl-morphine does not offer significant advantages compared to the standard epidural. Copyright © 2013 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved.

  4. Use of transcutaneous electrical nerve stimulation as an adjunctive to epidural analgesia in the management of acute thoracotomy pain

    Directory of Open Access Journals (Sweden)

    Alka Chandra

    2010-01-01

    Full Text Available The present randomized study was conducted in our institute of pulmonary medicine and tuberculosis over a period of 1 year. This study aimed to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS as an adjunctive to thoracic epidural analgesia for the treatment of postoperative pain in patients who underwent posterolateral thoracotomy for decortication of lung. Sixty patients in the age group 15-40 years scheduled to undergo elective posterolateral thoracotomy were divided into two groups of 30 each. Patients were alternatively assigned to one of the groups. In group I, only thoracic epidural analgesia with local anaesthetics was given at regular intervals; however, an identical apparatus which did not deliver an electric current was applied to the control (i.e. group I patients. While in group II, TENS was started immediately in the recovery period in addition to the epidural analgesia. A 0-10 visual analog scale (VAS was used to assess pain at regular intervals. The haemodynamics were also studied at regular intervals of 2 h for the first 10 h after the surgery. When the VAS score was more than three, intramuscular analgesia with diclofenac sodium was given. The VAS score and the systolic blood pressure were comparable in the immediate postoperative period (P = NS but the VAS score was significantly less in group II at 2, 4, 6, 8 h (P < 0.01, P < 0.05, P < 0.05, P < 0.05, respectively, and at 10 h the P value was not significant. Similarly, the systolic blood pressure was significantly less in group II at 2, 4, 6 h after surgery, that is P < 0.02, P < 0.01, P < 0.01, respectively, but at 8 and 10 h the pressures were comparable in both the groups. Adding TENS to epidural analgesia led to a significant reduction in pain with no sequelae. The haemodynamics were significantly stable in group II compared to group I. TENS is a valuable strategy to alleviate postoperative pain following thoracic surgery with no side

  5. Bupivacaine in combination with fentanyl or sufentanil in epidural/intrathecal analgesia for labor: a meta-analysis.

    Science.gov (United States)

    Li, Bo; Wang, Huixia; Gao, Chengjie

    2015-05-01

    This study is to compare the effectiveness of combinational use of bupivacaine with fentanyl (BUPI-FEN) and sufentanil (BUPI-SUF) in epidural/intrathecal analgesia for labor. Electronic databases were searched for relevant research papers published between 1985 and 2014. Meta-analyses of mean differences or odds ratios were performed and statistical heterogeneity between the studies tested by I(2) index. Ten studies recruiting a total of 728 women in labor were selected. Concentrations of the anesthetics used as mean ± sd were bupivacaine 0.115 ± 0.056%, fentanyl 0.0007 ± 0.001%, and sufentanil 0.00017 ± 0.00022%. Duration of analgesia was not significantly different between BUPI-SUF and BUPI-FEN administered mothers (mean difference [95%CI] of -33.55 [-74.94, 7.83] minutes; P = .11) under random effects. The onset of analgesia was also not significantly different between both groups (mean difference [95%CI] of -0.61 [-1.38, 0.16] minutes; P = .12). The number of neonates with Apgar score bupivacaine provide similar analgesic properties via the epidural or intrathecal routes for labor pain relief.

  6. Clinical assessment of epidural analgesia induced by xylazine-lidocaine combination accompanied by xylazine sedation in calves

    Directory of Open Access Journals (Sweden)

    Kamiloglu Alkan

    2005-10-01

    Full Text Available The aim of the present study was to investigate whether epidural administration of a xylazine-lidocaine combination accompanied by xylazine sedation would provide satisfactory analgesia for some surgical procedures on 10 calves admitted to the Department of Veterinary Surgery, University of Kafkas with perineal urolithiasis (n:2, rectovaginal fistula (n:1, atresia ani (n:2, omphalophlebitis (n:2, omphaloarteritis (n:1 and umbilical hernia (n:2. Following intramuscular injection of xylazine at a dose of 0.05 mg/kg for sedation, xylazine-lidocaine combination (0.2 mg/kg lidocaine + 0.02 mg/kg xylazine + 5 ml 0.9% NaCl was administrated into the lumbosacral (L6-S1, sacrococcygeal (S5-Co1 or intercoccygeal (Co1-Co2 space. Heart rate, respiratory rate and rectal temperature were recorded prior to and during analgesia at 5, 10, 15, 30 and 60 minutes. Furthermore, depth and duration of analgesia were evaluated during surgical intervention. The study revealed that the combination of epidural xylazine-lidocaine with xylazine sedation was highly satisfactory for surgery of the lower urinary tract and the perineal region, but it was less so for surgery of the umbilical area.

  7. Clinical assessment of epidural analgesia induced by xylazine-lidocaine combination accompanied by xylazine sedation in calves

    Science.gov (United States)

    2005-01-01

    The aim of the present study was to investigate whether epidural administration of a xylazine-lidocaine combination accompanied by xylazine sedation would provide satisfactory analgesia for some surgical procedures on 10 calves admitted to the Department of Veterinary Surgery, University of Kafkas with perineal urolithiasis (n:2), rectovaginal fistula (n:1), atresia ani (n:2), omphalophlebitis (n:2), omphaloarteritis (n:1) and umbilical hernia (n:2). Following intramuscular injection of xylazine at a dose of 0.05 mg/kg for sedation, xylazine-lidocaine combination (0.2 mg/kg lidocaine + 0.02 mg/kg xylazine + 5 ml 0.9% NaCl) was administrated into the lumbosacral (L6-S1), sacrococcygeal (S5-Co1) or intercoccygeal (Co1-Co2) space. Heart rate, respiratory rate and rectal temperature were recorded prior to and during analgesia at 5, 10, 15, 30 and 60 minutes. Furthermore, depth and duration of analgesia were evaluated during surgical intervention. The study revealed that the combination of epidural xylazine-lidocaine with xylazine sedation was highly satisfactory for surgery of the lower urinary tract and the perineal region, but it was less so for surgery of the umbilical area. PMID:21851664

  8. The Effects of Thoracic Epidural Analgesia on Postoperative Pain and Myocardial Protection in Coronary Artery Bypass Surgery

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    Bestami Barış Çelik

    2015-03-01

    Full Text Available Aim: Thoracic epidural analgesia (TEA in cardiac surgery provides stable hemodynamics and postoperative analgesia by reducing stress response. The aim of this study was to investigate the effects of TEA in coronary artery bypass grafting (CABG on postoperative pain, myocardial protection, intensive care unit (ICU and hospital length of stay. Methods: After receiving approval from the hospital scientific committee and obtaining written informed consent from the participants, 40 patients, who were undergoing elective CABG, were included in the study. The patients were prospectively randomized into two groups as TEA group (n=20 and control group (n=20. Epidural catheters were placed one day before surgery at the T5-T6 level, levobupivacaine 2 µg/mL and fentanyl 5 mL/hr infusions were initiated in the ICU. Control group received intravenous infusion of fentanyl 8 µg/kg/hr. Infusions continued for 24 hours in both groups. Results: Time to extubation was shorter, postoperative hypertension was less frequent and pain scores were lower in TEA group than in control group (p<0.01. There was no difference in length of stay in the ICU, CK-MB and troponin I levels between the groups, however, length of hospital stay was shorter in TEA group. Conclusion: TEA with levobupivakain in CABG was found to provide stable hemodynamics, effective analgesia and to shorten length of hospital stay. (The Medical Bulletin of Haseki 2015; 53: 72-6

  9. Thoracic epidural analgesia for off-pump coronary artery bypass surgery in patients with chronic obstructive pulmonary disease.

    Science.gov (United States)

    Mehta, Yatin; Vats, Mayank; Sharma, Munish; Arora, Reetesh; Trehan, Naresh

    2010-01-01

    The benefits of thoracic epidural analgesia in patients undergoing coronary artery bypass grafting are well documented. However, the literature available on the role of high thoracic epidural analgesia (HTEA) in patients with chronic obstructive pulmonary disease undergoing off-pump coronary artery bypass graft (OPCAB) surgery is scarce. We conducted a randomized clinical trial to establish whether HTEA is beneficial in patients with chronic obstructive pulmonary disease undergoing elective OPCAB surgery. After institutional ethics board approval and informed consent, 62 chronic obstructive pulmonary disease patients undergoing elective OPCAB were randomly grouped into two (n = 31 each). Both groups received general anesthesia (GA), but in the HTEA group patients, TEA was also administered. Standardized surgical and anesthetic techniques were used for both the groups. Pulmonary function tests were performed pre-operatively, 6 h and 24 h post-extubation and on days 2, 3, 4 and 5 along with arterial blood gas analysis (ABG) analysis. Time for extubation (h) and time for oxygen withdrawal (h) were recorded. Pain score was assessed by the 10-cm visual analogue scale. All hemodynamic/oxygenation parameters were noted. Any complications related to the TEA were also recorded. Patients in the HTEA group were extubated earlier (10.8 h vs. 13.5 h, P chronic obstructive pulmonary disease patients undergoing elective OPCAB surgery, HTEA is a good adjunct to GA for early extubation, faster recovery of pulmonary function and better analgesia.

  10. Pharmacological strategies to reduce pruritus during postoperative epidural analgesia after lumbar fusion surgery - a prospective randomized trial in 150 patients

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    Robinson Yohan

    2011-05-01

    Full Text Available Abstract Background Epidural analgesia with bupivacain, epinephrine and fentanyl provides excellent pain control after lumbar fusion surgery, but pruritus and motor block are frequent side effects. Theoretically epidural ropivacain combined with oral oxycodone could decrease the incidence of these side effects. The two regimens were compared in a prospective randomized trial. Patients and methods 150 patients (87 women treated with posterior instrumented lumbar fusion were included. The mean age was 51 +/- 11 years. 76 were randomized to bupivacain, epinephrine and fentanyl (group B and 74 to ropivacain and oxycodone (group R. Pruritus, motor block and pain were measured 6 hours after surgery, thereafter 6 times per day for 5 days. Any pain breakthrough episode was registered whenever it occurred. Results The epidural treatment could be performed in 143 patients (72 in group B and 71 in group R. Disturbing pruritus occurred in 53 patients in group B compared to 12 in group R (p Conclusions Pruritus could be reduced with a combination of epidural ropivacain and oral oxycodone, at the price of a slightly higher pain level. Ropivacaine was not found to be superior to bupivacaine with regard to motor blocks.

  11. Survey of the Factors Associated with a Woman's Choice to Have an Epidural for Labor Analgesia

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    Jennifer Harkins

    2010-01-01

    Full Text Available Objectives. The purpose of this study was to determine the factors associated with whether a woman received an epidural in labor and to determine the main source used to obtain information about labor epidurals. Methods. Over a one-month period, we surveyed all patients who labored, the day after their delivery. We used multiple logistic regression to identify potential predictive factors after initial univariate analysis. Results. 320 women who met enrollment criteria delivered during the study period and 94% completed the study. Of the 302 patients surveyed, 80% received an epidural for labor. Univariate analysis showed the following variables were associated with whether women received an epidural (P<.01: partner preference, prior epidural, language, education, type of insurance, age, duration, and pitocin use. Using computed multiple logistic regression only partner preference and prior epidural were associated with whether women received an epidural. Conclusion. It was not surprising that a previous epidural was predictive of a patient receiving an epidural. The strong association with partner preference and epidural use suggests this is an important factor when counseling pregnant women with regard to their decision to have a labor epidural.

  12. Analysis of stages of labor, stress indexes and coagulation function in dexmedetomidine combined with regular discontinuous epidural injection for labor analgesia

    Institute of Scientific and Technical Information of China (English)

    Jing-Yi Zhang; Yu-Qiang Su; Ke-Xin Du

    2016-01-01

    Objective:To study the changes in stages of labor, stress indexes and coagulation function in dexmedetomidine combined with regular discontinuous epidural injection for labor analgesia. Methods:A total of 128 cases of full-term primiparas receiving epidural labor analgesia in our hospital between May 2013 and December 2015 were randomly divided into the dexmedetomidine (Dex group) and control group, the analgesia method for Dex group was dexmedetomidine combined with regular discontinuous epidural injection, and the analgesia method for control group was regular discontinuous epidural injection. The analgesic effect, time of stages of labor as well as stress indexes and coagulation function indexes in serum were evaluated.Results:The analgesic onset time and effective time of Dex group were significantly shorter than those of control group, the hold time was significantly longer than that of control group, latency time was not different from that of control group, and the time of the second stage of labor and the time of the third stage of labor were significantly shorter than those of control group; in the second and third stages of labor, blood glucose, blood cortisol, blood insulin, epinephrine and norepinephrine content of Dex group were significantly lower than those of control group; 24 h after childbirth, PT, APTT and TT of Dex group were significantly longer than those of control group, and FIB and D-D content were significantly lower than those of control group.Conclusions:Compared with epidural labor analgesia, the dexmedetomidine combined with regular discontinuous epidural injection can improve the analgesic effect, promote the progress of labor and reduce stress reaction as well as postpartum hypercoagulable state, and it is a more ideal solution for labor analgesia.

  13. Colonic resection with early discharge after combined subarachnoid-epidural analgesia, preoperative glucocorticoids, and early postoperative mobilization and feeding in a pulmonary high-risk patient

    DEFF Research Database (Denmark)

    Møiniche, S; Dahl, J B; Rosenberg, J

    1994-01-01

    BACKGROUND AND OBJECTIVES. A pulmonary high-risk patient undergoing right hemicolectomy for cancer was treated with a combination of intense afferent neural block with subarachnoid-epidural local anesthetics followed by continuous epidural analgesia, preoperative high-dose glucocorticoids......) with unchanged pulmonary function. Nocturnal episodic oxygen desaturation, hyperthermia, and postoperative fatigue were prevented. Defecation occurred on the first postoperative day and oral caloric intake was normal after 24 hours with no postoperative weight loss. Self care was normalized on the third...

  14. Analgesic Choice in Management of Rib Fractures: Paravertebral Block or Epidural Analgesia?

    Science.gov (United States)

    Malekpour, Mahdi; Hashmi, Ammar; Dove, James; Torres, Denise; Wild, Jeffrey

    2017-06-01

    Rib fractures are commonly encountered in the setting of trauma. The aim of this study was to assess the association between the clinical outcome of rib fracture and epidural analgesia (EA) versus paravertebral block (PVB) using the National Trauma Data Bank (NTDB). Using the 2011 and 2012 versions of the NTDB, we retrieved completed records for all patients above 18 years of age who were admitted with rib fractures. Primary outcome was in-hospital mortality. Secondary outcomes were length of stay (LOS), intensive care unit (ICU) admission, ICU LOS, mechanical ventilation, duration of mechanical ventilation, development of pneumonia, and development of any other complication. Clinical outcomes were first compared between propensity score-matched EA and PVB patients. Then, EA and PVB patients were combined into the procedure group and the outcomes were compared with propensity score-matched patients that received neither intervention (no-procedure group). A total of 194,766 patients were included in the study with 1073 patients having EA, 1110 patients having PVB, and 192,583 patients having neither procedure. After propensity score matching, comparison of primary and secondary outcomes between EA and PVB patients showed no difference. Comparison of propensity score-matched procedure and no-procedure patients showed prolonged LOS and more frequent ICU admissions in patients receiving a procedure (both P rib fractures. There was an association between use of a block and improved outcome, but this could be explained by selection of healthier patients to receive a block. Prospective study of this association is recommended.

  15. ROPIVACAINE CONTINUOUS WOUND INFUSION VERSUS CONTINUOUS EPIDURAL VERSUS SYSTEMIC ANALGESIA FOR POST CAESAREAN DELIVERY UNDER SPINAL ANAESTHESIA: A PROSPECTIVE RANDOMISED CONTROLLED STUDY

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    Paleti

    2014-07-01

    Full Text Available BACKGROUND: Opioid based analgesic regimens have been the gold standard for post caesarean analgesia until recently. Regional techniques like local intra-wound infusion techniques are becoming popular now. Our aim is to evaluate the efficacy of 0.2% Ropivacaine continuous wound infusion versus continuous epidural versus conventional systemic analgesia for post caesarean delivery. METHODOLOGY: 60 healthy parturients of ASA I/II were randomized after elective caesarean section into 3 groups of 20 each. Group-A: Received 0.2% Ropivacaine via an epidural catheter placed into subcutaneous tissue and fascia before skin closure at the rate of 5ml/hr. through infusion pump. Group-B: Received 0.2% Ropivacaine continuous epidural infusion via an epidural catheter at the rate of 8ml/hr. An initial bolus of 10ml was given in groups A&B. Group-C: Received standard systemic analgesia with diclofenac sodium and rescue opioid. Post operatively parturients were assessed for VAS scores for pain at rest and during movement, total Ropivacaine consumption, Tramadol consumption and side effects. Data were analyzed using SPSS software version 22. RESULTS: There were no significant differences in the mean VAS scores at rest and at movement between groups A or B and C. The consumption of Tramadol was significantly greater in Group C (p value AC=0.025, BC=0.0000 than A or B. Mean Ropivacaine consumption is significantly higher in Group B (p=0.000 than Group A. CONCLUSION: Continuous local intra-wound analgesia with Ropivacaine produced comparable analgesia to that of continuous epidural and superior analgesia compared to standard systemic analgesia.

  16. The use of botulinum toxin and epidural analgesia for the treatment of spasticity and pain in a patient with maple syrup urine disease

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    Abdullah M Kaki

    2012-01-01

    Full Text Available A 7-year-old boy, weighing 18 kg, was diagnosed with maple syrup urine disease (MSUD. He suffered from spasticity of the lower limbs and pain that did not respond to oral medications. Injections of botulinum toxin A (BTX-A at 10 sites and epidural analgesia with 0.125% bupivacaine were used to treat spasticity with good results. We conclude that BTX-A combined with epidural analgesia may be a useful treatment option for incapacitating, painful spasticity related to MSUD. This treatment modality allowed a comprehensive rehabilitation program to be completed and it lasted longer than 9 months.

  17. A clinical study of the effectiveness of continuous epidural labour analgesia for vaginal delivery with 0.0625% bupivacaine with 0.0002% fentanyl

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    Vijay Kanna

    2015-10-01

    Results: The onset of analgesia was significantly faster in 0.0625% bupivacaine with 0.0002% fentanyl (9.7 minutes. A greater proportion of parturient achieved a maximum level of analgesia unto T8. The duration of analgesia was also significantly longer. The effectiveness of analgesia was better. There were no significant cardiovascular changes or any motor blockade. The side effects were mild sedation and in the parturient who received fentanyl. The mode of delivery and the Apgar scores of the neonates at 1 and 5 minutes were comparable. Conclusions: It was concluded that continuous lumbar epidural analgesia with 8 ml of 0.0625% bupivacaine with 2 and micro;g of fentanyl improved the quality and duration of analgesia without producing any adverse effects on the mother or on the neonate. [Int J Res Med Sci 2015; 3(10.000: 2553-2560

  18. Immediate and prolonged effects of pre- versus postoperative epidural analgesia with bupivacaine and morphine on pain at rest and during mobilisation after total knee arthroplasty

    DEFF Research Database (Denmark)

    Dahl, J B; Daugaard, J J; Rasmussen, B;

    1994-01-01

    Thirty-two patients scheduled for total knee arthroplasty were randomized to receive an identical epidural blockade initiated 30 min before surgical incision (N = 16), or at closure of the surgical wound (N = 16). Before induction of general anaesthesia the epidural catheter was tested...... with bupivacaine 7.5 mg.ml-1, 2 ml. General anaesthesia was induced with thiopentone, pancuronium or atracurium, and fentanyl 0.1-0.3 mg, and maintained with N2O/O2 and enflurane. The epidural regimen consisted of a bolus of 16 ml of bupivacaine 7.5 mg.ml-1 plus morphine 2 mg, and continuous infusion......, during or after cessation of the epidural regimen. These results do not suggest timing of analgesia with a conventional, continuous epidural regimen to be of major clinical importance in patients undergoing total knee arthroplasty....

  19. Intra-operative Patient-Controlled Sedation (PCS:Propofol versus Midazolam Supplementation During Epidural Analgesia (Clinical and Hormonal Study

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    Hassan S Al-khayat

    2008-01-01

    Full Text Available This study was done on sixty adult males scheduled to have an epidural analgesia for elective inguinal hernia repair. The study was designed to compare propofol and midazolam with regard to their suitability for the patient-controlled sedation (PCS technique during epidural analgesia. Patients were divided into three equal groups and premedicated with 0.2mg.kg -1 oral midazolam. Group I (G1 served as control. Using PCS technique, the pump was programmed to deliver on demand a bolus dose of 0.5 mg.kg- 1 of propofol in Group II (G2 or 0.1mg.kg -1 midazolam in Group III(G3. Patient′s sedation status was assessed by sedation score, comfort scale and by psychometric testing. The total delivered dose of each tested drug was calculated. Serum concentrations of propfol and midazolam, plasma cortisol and free fatty acids were measured. Propofol and midazolam PCS technique produced excellent and easily controllable sedation. The dose needed to produce steady state sedation was 2.8±1.42 and 0.11±0.6 mg.kg -1 .h- 1 for propofol and midazolam respectively. Propofol was more suitable than midazolam for PCS because of its rapid onset, favorable recovery profile and low side effects. PCS proved to be a stress-free and acceptable technique.

  20. [Factors justifying the choice of labor epidural analgesia by nulliparous women: experience at a maternity center in Antananarivo, Madagascar].

    Science.gov (United States)

    Ramorasata, J A C; Raveloson, N E; Randriamahavonjy, R; Tohaina, D; Keita, H

    2011-10-01

    Epidural analgesia is the most effective method for pain relief during labor. This 10-year exploratory descriptive study on factors underlying women's decisions to request or refuse labor epidural analgesia (LEA) was carried out at a level III maternity hospital in Antananarivo, Madagascar. All patients underwent a pre-anesthesia check-up (PAC) between 32 and 34 weeks of amenorrhea. During the PAC, a questionnaire was administered to determine socio-economic aspects, level of education, and knowledge about labor pain and LEA. In addition, LEA was proposed and patients were asked to explain their reasons for accepting or refusing the procedure. The purpose of this report was to describe the factors underlying acceptance or refusal of EA by nulliparous women. A total of 41 nulliparous women were included. Fourteen (34.14%) accepted LEA and 27 (63.86%) refused. Mean age was 27 years in the acceptance group and 25 years in the refusal group. No patient had good knowledge about LEA. Nulliparous women that accepted EA had a higher socio-economic level, expected stronger labor pain, were better informed about EA, and expressed greater confidence in medical care. In addition to economic aspects, the main reasons for refusing EA involved fear and family background.

  1. Pulmonary function and stress response after laparoscopic cholecystectomy: comparison with subcostal incision and influence of thoracic epidural analgesia.

    Science.gov (United States)

    Rademaker, B M; Ringers, J; Odoom, J A; de Wit, L T; Kalkman, C J; Oosting, J

    1992-09-01

    Laparoscopic cholecystectomy (LPC) is increasingly used to treat symptomatic cholelithiasis. We compared the effects of cholecystectomy by subcostal incision to those of LPC on lung function and endocrine metabolic response. The effects of thoracic epidural analgesia for LPC were studied as well. Thirty patients undergoing elective cholecystectomy under general anesthesia were allocated to three study groups: group I, cholecystectomy by subcostal incision; group II, LPC; group III, LPC and epidural analgesia with 0.5% bupivacaine with epinephrine, followed by continuous epidural infusion of 6 mL of 0.5% bupivacaine. Forced vital capacity (FVC), peak expiratory flow, and forced expiratory volume in 1 s were measured with the patients in a half-sitting position. In all groups, sustained decreases in FVC, forced expiratory volume in 1 s, and peak expiratory flow were observed up to 24 h after surgery. Reduction of FVC was significantly more in group I compared with groups II and III (P less than 0.05). The FVC in group I decreased from 3.8 +/- 0.42 (SD) to 1.1 +/- 0.27 L (P less than 0.01), in group II from 3.6 +/- 1.46 to 2.1 +/- 0.94 L (P less than 0.05), and in group III from 3.8 +/- 0.92 to 2.8 +/- 0.90 L (P less than 0.05). In all groups, plasma glucose and cortisol increased after surgery compared with baseline levels (P less than 0.05). At 240 min after surgery, a small but significant decrease of cortisol was measured in group III (P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

  2. Postoperative analgesia with intramuscular morphine at fixed rate versus epidural morphine or sufentanil and bupivacaine in patients undergoing major abdominal surgery

    NARCIS (Netherlands)

    Broekema, AA; Veen, A; Fidler, [No Value; Gielen, MJM; Hennis, PJ

    1998-01-01

    We assessed the efficacy and side effects of postoperative analgesia with three different pain regimens in 90 patients undergoing major abdominal surgery. The patients were randomly assigned to one of three groups: epidural morphine (EM) or sufentanil (ES), both combined with bupivacaine, or IM morp

  3. Differences in the Frequency of Use of Epidural Analgesia between Immigrant Women of Turkish Origin and Non-Immigrant Women in Germany – Explanatory Approaches and Conclusions of a Qualitative Study

    Science.gov (United States)

    Petruschke, I.; Ramsauer, B.; Borde, T.; David, M.

    2016-01-01

    Introduction: The starting point of this study was the considerably lower rate of epidural analgesia use among women of Turkish origin in Germany compared to non-immigrant women in the German Research Foundation (DFG)-funded study entitled “Perinatal Health and Migration Berlin”. The study aimed to identify possible differences in the womenʼs attitudes towards epidural analgesia. Methods: Exploratory study with semi-structured interviews, interviews lasting 17 minutes on average were conducted with 19 women of Turkish origin and 11 non-immigrant women at a Berlin hospital. The interviews were subjected to a qualitative content analysis. Results: Immigrant women of Turkish origin in Germany more frequently ascribe meaning to the pain associated with vaginal delivery. They more frequently categorically reject the use of epidural analgesia, 1) for fear of long-term complications such as paralysis and back pain and 2) based on the view that vaginal delivery with epidural analgesia is not natural. Information on epidural analgesia is frequently obtained from a variety of sources from their social setting, in particular, by word of mouth. The women in both groups stated that they would take the decision to use epidural analgesia independent of their partnerʼs opinion. Discussion: The differences in epidural analgesia use rates observed correspond to the womenʼs attitudes. For the immigrant women of Turkish origin in Germany, the attitude towards using epidural analgesia is based in part on misinformation. In order to enable the women to make an informed decision, epidural analgesia could receive a stronger focus during childbirth courses. PMID:27681522

  4. Algorithm for the anesthetic management of cesarean delivery in patients with unsatisfactory labor epidural analgesia [v1; ref status: indexed, http://f1000r.es/5a3

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    Sonia Vaida

    2015-04-01

    Full Text Available The management of a patient presenting with unsatisfactory labor epidural analgesia poses a severe challenge for the anesthetist wanting to provide safe anesthetic care for a cesarean delivery. Early recognition of unsatisfactory labor analgesia allows for replacement of the epidural catheter. The decision to convert labor epidural analgesia to anesthesia for cesarean delivery is based on the urgency of the cesarean delivery, airway examination, and the existence of a residual sensory and motor block.  We suggest an algorithm which is implemented in our department, based on the urgency of the cesarean delivery.

  5. COMPARISON OF EPIDURAL BUPIVACAINE; FENTANYL AND THEIR COMBINATION FOR POSTOPERATIVE ANALGESIA IN LOWER ABDOMINAL AND LOWER EXTREMITY SURGERY: A PROSPECTIVE, RANDOMIZED, DOUBLE BLIND CONTROLLED TRIAL

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    Purba

    2016-03-01

    Full Text Available BACKGROUND Epidural analgesia with local anaesthetics and opioids provide good control of postoperative pain in lower abdominal and lower extremity surgery. AIM To evaluate and compare the analgesic action and adverse effects of epidural bupivacaine, fentanyl and their combination in postoperative period. METHODS 75 patients undergoing elective infraumbilical surgery were allocated in three groups in a randomized double blinded fashion. Postoperative analgesia was maintained with continuous infusion of epidural drug in the following manner: Group B: Injection Bupivacaine 0.125% @ 0.1mL/kg/hr through epidural route; Group F: Injection Fentanyl 4µg/mL @ 0.1mL/kg/hr through epidural route; Group BF: Injection Bupivacaine 0.0625% and Fentanyl 2µ/mL @ 0.1mL/kg/hr through epidural route. RESULTS VAS score were almost similar in all three groups at 00, 04, 08hrs and not clinically significant at that point of time. VAS score showed significant difference at 12, 20 and 24 hrs, being persistently lower in Gr BF than Gr B and Gr F. According to VRS Scale Score at 04 hrs majority of patients of all three groups had mild-to-moderate pain (p=0.278. At 08 hrs, 24% (p=0.082, 12 hrs 60% (<0.001, 16 hrs 68% (<0.001, 20 hrs 88% (<0.001 and 24 hrs 84% (<0.001 of Gr BF patients were pain free which are clinically significant. At the end of 08, 12, 16, 20, 24 postoperative hours, no patients of any groups had residual motor paralysis. Rescue analgesic needed in Gr BF patients were significantly less than other two groups. CONCLUSION Combined bupivacaine and fentanyl infusion through an epidural route provides better analgesia in comparison to bupivacaine and fentanyl alone. Total drug, rescue analgesic requirement and adverse effects are much lower in combined group.

  6. 蛛网膜下腔联合硬膜外腔阻滞用于分娩镇痛时机的探讨%Occasion of Administration of Combined Spinal Epidural Analgesia and Patient-control Epidural Analgesia on Labor—Latent Stage Analgesia versus Active Stage Analgesia

    Institute of Scientific and Technical Information of China (English)

    范建辉; 滕奔琦; 李萍; 李晓芸; 朱娟

    2011-01-01

    摘要:[目的]探讨实施蛛网膜下腔阻滞-硬膜外联合分娩镇痛时机对产程和分娩结局的影响.[方法]370例产妇按照宫颈口开张程度分为2组,潜伏期组130例在宫颈口开张l ~2 cm时开始实施蛛网膜下腔阻滞-硬膜外联合镇痛,活跃期组240例在宫颈口开张3~8cm时开始实施镇痛,记录2组产妇年龄、孕周、孕次、产程、分娩方式、缩宫素应用情况、产后24h出血量、胎儿窘迫、羊水粪染、新生儿体质量及新生儿生物物理评分(即1 min及5 min Apgar评分)、新生儿黄疸.[结果]潜伏期组和活跃期组比较,潜伏期延长[(453±203)min vs,(338±182)min,P=0.000].活跃期组的活跃期时间明显延长[(229±109) min vs (197±101)min,P=0.011].第2、3产程和总产程比较差异无统计学意义(P=0.200,P=0.222,P=0.091).潜伏期组的缩宫素使用率较高(43.08%vs 23.33%,P=0.012).两组器械助产率、剖宫产率、产后24h出血量比较差异无统计学意义(P>0.05).胎儿窘迫率、新生儿生物物理评分、新生儿高胆红素血症发生率2组比较差异无统计学意义(P>0.05).[结论]潜伏期实施联合分娩镇痛可能抑制子宫收缩、延长潜伏期,正确使用缩宫索可以减少分娩镇痛带来的不利影响.%[Objective]This study was designed to explore whether combined spinal-epidural analgesia (CSEA) and patient-control epidural analgesia (PCEA ) has influence on labor progress and adverse events between latent stage analgesia and active stage analgesia. [Methods] The subjects were divided into two groups; latent stage analgesia group ( 130 cases) received CSEA+PCEA in latent phase (cervical dilatation was 0.05). There were no significant differences in the rate of fetal distress or neonatal Apgar scorces and neonatal jaundice between the two groups (P > 0.05). [Conclusions] CSEA + PCEA in the latent phase was associated with an increased risk of inhibition of uterine contraction and prolonged

  7. Comparative analgesic and sedative effects of tramadol, tramadol-lidocaine and lidocaine for caudal epidural analgesia in donkeys (Equus asinus).

    Science.gov (United States)

    Marzok, Mohamed A; El-khodery, Sabry A

    2015-03-01

    To compare anti-nociceptive and sedative effects of tramadol, a combination of tramadol-lidocaine, and lidocaine alone for perineal analgesia in donkeys. Experimental 'blinded' randomized cross-over study. Six healthy adult donkeys. Treatments were tramadol (TR) (1.0 mg kg(-1) ), tramadol-lidocaine (TRLD) (0.5 and 0.2 mg kg(-1) respectively) and lidocaine (LD) (0.4 mg kg(-1) ) given into the epidural space. The volume of all treatments was 0.02 mL kg(-1) . Nociception was tested at the perineal region by pin prick, followed, if no reaction, by pressure from a haemostat clamp. Times to onset, degree and duration of anti-nociception of the perineal region were recorded. Response was tested immediately after drug administration and at: 2, 5, 10, 15, 30, 45, and 60 minutes post-administration and then at 30 minute intervals thereafter until a response re-occurred. Physiologic data and degree of sedation and ataxia were recorded pre-administration and at intervals for 240 minutes post-administration. Results were analyzed using anova, Kruskal-Wallis tests, and Wilks' Lambda test as relevant. Significance was taken as p < 0.05. Times (minutes, mean ± SD) to onset and duration of anti-nociception, respectively were; TR 13 ± 1.6 and 220 ± 4.6; TRLD 6 ± 0.8 and 180 ± 8.5; LD 4 ± 1.4 and 75 ± 4. Onset and duration times were significantly longer with TR than the other two treatments. TR never produced complete anti-nociception, whereas the TRLD and LD induced complete anti-nociceptive effects. Duration was significantly longer with TRLD than with LD alone. Epidural injections of TR and TRLD induced mild sedation. Epidural combination of TRLD produced an anti-nociceptive effect in the perineum, which was rapid in onset and had a longer duration of action than LD alone. An epidural single dose of TRLD combination would appear to provide an acceptable analgesic effect in the perineal region of donkeys. © 2014 Association of Veterinary

  8. Epidural anaesthesia and analgesia - effects on surgical stress responses and implications for postoperative nutrition

    DEFF Research Database (Denmark)

    Holte, Kathrine; Kehlet, H

    2002-01-01

    for improved mobilization and oral nutrition, and preservation of body composition and muscle function. Studies integrating continuous epidural local anaesthetics with enforced early nutrition and mobilization uniformly suggest an improved recovery, decreased hospital stay and convalescence. CONCLUSIONS......: Epidural local anaesthetics should be included in a multi-modal rehabilitation programme after major surgical procedures in order to facilitate oral nutrition, improve recovery and reduce morbidity....

  9. Effect of ropivacaine-fentanyl combined with spinal-epidural labor analgesia on maternal serum markers andTXB2/6-Keto-PGF1α proportion

    Institute of Scientific and Technical Information of China (English)

    Yan Huang

    2015-01-01

    Objective:To study the effect of ropivacaine-fentanyl combined with spinal–epidural labor analgesia on maternal serum markers and TXB2/6-Keto-PGF1α proportion.Methods:40 cases of puerperas intending to receive vaginal delivery in our hospital were randomly divided into two groups. Combined group received fentanyl subarachnoid injection combined with ropivacaine epidural injection and control group received fentanyl combined with ropivacaine epidural injection. Then levels of serum pain mediators and inflammation related factors as well as TXB2/6-Keto-PGF1α proportion of both groups were detected. Results:In delivery process, contents of serum pain mediatorsβ-EP, NO, SP, PGE2, TNF-α, IL-6, CCL2 and CCR2 of combined group were significantly lower than those of control group, and IL-10 and TGb-βcontents were significantly higher than those of control group; In and after labor, serum TXB2 content and TXB2/6-keto-PGF1α proportion of combined group were lower than those of control group, while 6-keto-PGF1α content was higher than that of control group.Conclusion:Ropivacaine-fentanyl combined with spinal–epidural labor analgesia can achieve more precise analgesia effect, reduce contents of pain mediators, pro-inflammatory cytokines and chemokines, and regulate TXB2/6-Keto-PGF1ααbalance.

  10. Intercostal nerve cryoablation versus thoracic epidural catheters for postoperative analgesia following pectus excavatum repair: Preliminary outcomes in twenty-six cryoablation patients.

    Science.gov (United States)

    Keller, Benjamin A; Kabagambe, Sandra K; Becker, James C; Chen, Y Julia; Goodman, Laura F; Clark-Wronski, Julianna M; Furukawa, Kenneth; Stark, Rebecca A; Rahm, Amy L; Hirose, Shinjiro; Raff, Gary W

    2016-12-01

    Multimodal pain management strategies are used for analgesia following pectus excavatum repair. However, the optimal regimen has not been identified. We describe our early experience with intercostal cryoablation for pain management in children undergoing the Nuss procedure and compare early cryoablation outcomes to our prior outcomes using thoracic epidural analgesia. A multi-institutional, retrospective review of fifty-two patients undergoing Nuss bar placement with either intercostal cryoablation (n=26) or thoracic epidural analgesia (n=26) from March 2013 to January 2016 was conducted. The primary outcome was hospital length of stay. Secondary outcomes included telemetry unit monitoring time, total intravenous narcotic use, duration of intravenous narcotic use, and postoperative complications. Patients who underwent intercostal cryoablation had a significant reduction in the mean hospital length of stay, time in a monitored telemetry bed, total use of intravenous narcotics, and the duration of intravenous narcotic administration when compared to thoracic epidural patients. Cryoablation patients had a slightly higher rate of postoperative complications. Intercostal cryoablation is a promising technique for postoperative pain management in children undergoing repair of pectus excavatum. This therapy results in reduced time to hospital discharge, decreased intravenous narcotic utilization, and has eliminated epidurals from our practice. Retrospective study - level III. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Analgesia epidural para el trabajo de parto en gestante con esclerosis múltiple Epidural analgesia during labour of a patient with multiple sclerosis

    OpenAIRE

    M.J. Mayorga Buiza; F. Caba Barrientos; F. Suárez Cordero; M. Echevarría Moreno

    2010-01-01

    La Esclerosis Múltiple (EM), es una enfermedad del SNC siendo 2 veces más frecuente su aparición en mujeres, el 70% de ellas en edad fértil. Desde el punto de vista anestésico nos encontramos ante una enfermedad con elevada susceptibilidad neurológica que podría agravarse tanto por la propia cirugía, la técnica anestésica como por la medicación utilizada. Por otra parte se plantea como atender la demanda de analgesia para el trabajo de parto en mujeres con EM, que es el grupo de edad con mayo...

  12. Effects of labor analgesia on maternal and neonatal outcome by epidural low concentration of bupivacaine combined with anisodamine

    Institute of Scientific and Technical Information of China (English)

    Yang Xiaoli; Zhou Chunqin; Li Xiaogang; Shen Xiaodong; Zou Yuliang

    2008-01-01

    Objective To observe the effects of labor analgesia on maternal and neonatal outcome by epidural application of 0.125% bupivacaine combined with anisodamine on the labor stage, and modes of delivery and neonatal Apgar's score. Methods A total of 220 primiparaes with full-term pregnancy, monocyesis and fetal head presentation without any obstetrical or systematic complications were chosen and divided into analgesic group and control group (110 in each group). The mixture of bupivaeaine and anisodamine was injected into the epidural space of the parturients in the analgesic group while those patients in the control group did not receive any analgesics. Results The analgesic effect was satisfactory (91.8 %), and no side effects occurred in the second stage of labor. The instrument delivery rate was lower in the analgesic group, and there was no significant difference between the two groups in neonatal Apgar's score. Conclusion The method is feasible in clinic for labor pain relief without increasing the rate of dystocla and complications of delivery.

  13. Is epidural analgesia a risk factor for occiput posterior or transverse positions during labour?

    Science.gov (United States)

    Le Ray, Camille; Carayol, Marion; Jaquemin, Sébastien; Mignon, Alexandre; Cabrol, Dominique; Goffinet, François

    2005-11-01

    The aim of this study was to assess whether the station of the fetal head at epidural placement is associated with the risk of malposition during labour. Retrospective study (covering a 3-month period) of patients in labour with singleton cephalic term fetuses and epidural placement before 5 cm of dilatation. We studied the following risk factors for malposition: station and cervical dilatation at epidural placement, induction of labour, parity and macrosomia. Malposition, defined as all occiput posterior and occiput transverse positions, was assessed at 5 cm of dilatation because of our policy of systematic manual rotation for malpositions. The study included 398 patients, 200 of whom had malpositions diagnosed at 5 cm of dilatation. In both the univariate and multivariate analyses, station at epidural placement was the only risk factor significantly associated with this malposition (adjusted OR: 2.49, 95% CI 1.47-4.24). None of the other factors studied was significantly associated with malposition: nulliparity (OR 1.45, 95% CI 0.96-2.20), macrosomia (OR 0.75, 95% CI 0.37-1.50), induction of labour (OR 0.84, 95% CI 0.49-1.45), or dilatation less than 3 cm at epidural administration (OR 1.16, 95% CI 0.59-2.30). Only three infants of the 365 delivered vaginally (0.8%) were born in occiput posterior positions. Epidural placement when the fetal head is still "high" is associated with an increased rate of occiput posterior and transverse malpositions during labour.

  14. Bloqueio combinado raquiperidural versus bloqueio peridural contínuo para analgesia de parto em primigestas: resultados maternos e perinatais Combined spinal-epidural block versus continuous epidural block in labor analgesia for primiparous women: newborns and women outcomes

    Directory of Open Access Journals (Sweden)

    Márcio Antonio de Souza

    2009-10-01

    Full Text Available OBJETIVOS: comparar a evolução materna e perinatal após a utilização da analgesia peridural contínua versus analgesia combinada raqui-peridural em parturientes primigestas. MÉTODOS: foi realizado ensaio clínico aleatorizado com 128 gestantes primigestas em trabalho de parto, divididas em dois grupos: analgesia peridural (APC com 65 mulheres e grupo analgesia combinada raqui-peridural (ACRP com 63, admitidas no pré-parto de duas maternidades na cidade de Jundiaí - SP. Foram estudadas as variáveis: tempo de latência de instalação da analgesia, intensidade da dor e tempo total decorrido até a dilatação completa, índice de Apgar no primeiro e quinto minutos, tempo de resolução do parto, grau de bloqueio motor, efeitos adversos como náuseas, vômitos, prurido, hipotensão arterial, e grau de satisfação materna. Foram critérios de inclusão: primigestas, estado físico ASA 1 e 2, feto único, apresentação cefálica, de termo, dilatação cervical de 3 a 6 cm e solicitação de analgesia pelo obstetra. Foram excluídas mulheres com morbidades, ruptura de membranas, anormalidades fetais e uso de opioides até quatro horas antes. Para a análise estatística utilizou-se o teste de Mann-Whitney para as variáveis contínuas não paramétricas e os testes exato de Fisher e χ2 de Pearson, para variáveis categóricas. RESULTADOS: não houve diferença entre os grupos para velocidade de dilatação cervical, tempo para resolução do parto, parâmetros hemodinâmicos maternos, vitalidade do recém-nascido, complementações analgésicas durante o trabalho de parto e modo de parto. Houve maior rapidez de instalação da analgesia no grupo da ACRP e menor bloqueio motor no grupo de APC. Não foram observadas diferenças em relação aos efeitos adversos como náuseas, vômitos, prurido e hipotensão, sendo hipotensão mais frequente no grupo APC (16,9 versus 6,3% e náusea no grupo ACRP (6,3 versus 3,1%. CONCLUSÕES: as duas t

  15. Effect of combined spinal-epidural analgesia in labor on frequency of emergency cesarean delivery among nulliparous Chinese women.

    Science.gov (United States)

    Wang, Fen; Cao, Yun-Xia; Ke, Shan-Gao; Zhu, Tao-Hua; Zhang, Miao

    2016-12-01

    To determine whether combined spinal-epidural analgesia (CSEA) during labor increases the frequency of emergency cesarean delivery among Chinese nulliparous women. In a retrospective study, the medical records of nulliparous women with a singleton fetus in cephalic presentation who delivered at term at Tongling Maternity Hospital, China, between January 2012 and December 2014 were reviewed. Information about CSEA, mode of delivery, labor duration, oxytocin augmentation, and neonatal outcome was obtained. Logistic regression was used to examine independent associations between CSEA and emergency cesarean after controlling for confounding variables. Among 3456 women included, 1786 (51.7%) received CSEA and 1670 (48.3%) received no labor analgesia. Emergency cesarean was more frequent among CSEA users (219/1786 [12.3%]) than non-users (119/1670 [7.1%]; Pcesarean. After adjustment, women with CSEA maintained a slightly increased risk for cesarean (adjusted odds ratio 1.54, 95% confidence interval 1.20-2.00). Among Chinese nulliparous women, use of CSEA for labor pain was associated with an increased risk of emergency cesarean delivery; moreover, this effect was maintained after adjustment for other potential obstetric risk factors. Copyright © 2016 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  16. Factors affecting fetal bradycardia following combined spinal epidural for labor analgesia: a matched case-control study.

    Science.gov (United States)

    Cheng, Su Lin Maureen; Bautista, Dianne; Leo, Serene; Sia, Tiong Heng Alex

    2013-04-01

    The combined spinal epidural (CSE) technique for labor analgesia has become increasingly popular owing to its rapid onset of analgesia. However, incidences of fetal bradycardia following CSE have been reported. This study aimed to identify predictors of fetal bradycardia post CSE, such as a decrease in pain scores, the block height, Prostin (dinoprostone; Pfizer) use, and dosage of oxytocin. From May 2008 to October 2008, 29 patients were identified to have had an episode of fetal bradycardia. Each case was then matched to three controls, according to age and American Society of Anesthesiology status, selected from 2345 parturients who received a CSE during this period. A unit improvement in the pain score was associated with an increase in the odds of fetal bradycardia by 1.28 (95 % confidence interval [CI]: 1.02-1.60). In a second logistic regression model including sensory level higher than T9, the effect size remained consistent with an odds ratio of 1.22 (95 % CI: 0.97-1.53), supporting the theory that a higher level of sympathetic block (with a higher sensory block taken as a surrogate marker) results in an increased risk of fetal bradycardia. The dosage of oxytocin and the quantity of Prostin used were not found to be risk factors. The difference between pre- and post-CSE pain scores, and a higher sensory block height, which are surrogates for a greater degree of sympatholysis, were found to be risk factors for fetal bradycardia post CSE.

  17. Thoracic epidural analgesia for off-pump coronary artery bypass surgery in patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Mehta Yatin

    2010-01-01

    Full Text Available The benefits of thoracic epidural analgesia in patients undergoing coronary artery bypass grafting are well documented. However, the literature available on the role of high thoracic epidural analgesia (HTEA in patients with chronic obstructive pulmonary disease undergoing off-pump coronary artery bypass graft (OPCAB surgery is scarce. We conducted a randomized clinical trial to establish whether HTEA is beneficial in patients with chronic obstructive pulmonary disease undergoing elective OPCAB surgery. After institutional ethics board approval and informed consent, 62 chronic obstructive pulmonary disease patients undergoing elective OPCAB were randomly grouped into two (n = 31 each. Both groups received general anesthesia (GA, but in the HTEA group patients, TEA was also administered. Standardized surgical and anesthetic techniques were used for both the groups. Pulmonary function tests were performed pre-operatively, 6 h and 24 h post-extubation and on days 2, 3, 4 and 5 along with arterial blood gas analysis (ABG analysis. Time for extubation (h and time for oxygen withdrawal (h were recorded. Pain score was assessed by the 10-cm visual analogue scale. All hemodynamic/oxygenation parameters were noted. Any complications related to the TEA were also recorded. Patients in the HTEA group were extubated earlier (10.8 h vs. 13.5 h, P < 0.01 and their oxygen withdrawal time was also significantly lower (26.26 h vs. 29.87 h, P < 0.01. The VAS score, both at rest and on coughing, was significantly lower in the HTEA group at all times, post-operatively (P < 0.01. The forced vital capacity improved significantly at 6 h post-operatively in the HTEA group (P = 0.026 and remained significantly higher thereafter. A similar trend was observed in forced expiratory volume in the first second on day 2 in the HTEA group (P = 0.024. We did not observe any significant side-effects/mortality in either group. In chronic obstructive pulmonary disease patients

  18. Estudio comparativo de la eficacia analgésica del bloqueo continuo intercostal versus analgesia epidural torácica en la nefrectomía parcial abierta.

    OpenAIRE

    2014-01-01

    Un importante efecto secundario de la cirugía es el dolor agudo postoperatorio. La estrategia más utilizada en su control tras cirugía mayor abdominal ha sido la analgesia epidural. El desarrollo de las técnicas laparoscópicas ha provocado un aumento de casos que finalizan en cirugía abierta, para los que se están probando otras técnicas de control del dolor postoperatorio, como la analgesia perineural, utilizada en cirugía traumatológica, pero de la que hay poca experiencia en cirugía urológ...

  19. Combined Spinal-Epidural Analgesia for Laboring Parturient with Arnold-Chiari Type I Malformation: A Case Report and a Review of the Literature

    Directory of Open Access Journals (Sweden)

    Clark K. Choi

    2013-01-01

    Full Text Available Anesthetic management of laboring parturients with Arnold-Chiari type I malformation poses a difficult challenge for the anesthesiologist. The increase in intracranial pressure during uterine contractions, coughing, valsalva maneuvers, and expulsion of the fetus can be detrimental to the mother during the process of labor and delivery. No concrete evidence has implicated high cerebral spinal fluid pressure on maternal and fetal complications. The literature on the use of neuraxial techniques for managing parturients with Arnold-Chiari is extremely scarce. While most anesthesiologists advocate epidural analgesia for management of labor pain and spinal anesthesia for cesarean section, we are the first to report the use of combined spinal-epidural analgesia for managing labor pain in a pregnant woman with Arnold-Chiari type I malformation. Also, we have reviewed the literature and presented information from case reports and case series to support the safe usage of neuraxial techniques in these patients.

  20. Analgesia e sedacao durante a instalacao do cateter central de insercao periferica em neonatos

    Directory of Open Access Journals (Sweden)

    Priscila Costa

    2013-08-01

    Full Text Available Objetivou-se caracterizar as estratégias de analgesia e sedação em neonatos submetidos à instalação do cateter central de inserção periférica (CCIP e relacioná-las ao número de punções venosas, duração do procedimento e posicionamento da ponta do cateter. Estudo transversal com coleta prospectiva de dados, realizado em uma unidade de cuidados intensivos neonatais de um hospital privado na cidade de São Paulo, no período de 31 de agosto de 2010 a 01 de julho de 2011, em que foram avaliadas 254 inserções do CCIP. A adoção de estratégias analgésicas ou sedativas ocorreu em 88 (34,6% instalações do cateter e não esteve relacionada ao número de punções venosas, duração do procedimento ou posicionamento da ponta do cateter. As estratégias mais frequentes foram a administração endovenosa de midazolam em 47 (18,5% e fentanil em 19 (7,3% inserções do cateter. Recomenda-se maior adoção de estratégias analgésicas antes, durante e após o procedimento.

  1. PDCA循环在硬膜外分娩镇痛管理中的应用%Application of PDCA Cycle to the Management of Epidural Labor Analgesia

    Institute of Scientific and Technical Information of China (English)

    王晓霞; 朱广球; 陈玲萍

    2014-01-01

    Objective To explore the application of PDCA cycle to the quality management of epidural labor analgesia. Methods We applied PDCA cycle to the management of epidural labor analgesia from June, 2013 to January, 2014 and analyzed current situation. With plan, implementation, examination and action, we found out the problems in epidural labor analgesia and improved its quality continuously. Results The valid control rate of labor pain, satisfaction rating of pain-relieving and puerperae' satisfaction had been significantly improved after the application of PDCA cycle. Conclusion The application of PDCA cycle in epidural labor analgesia management could well improve the analgesic effect and patients' satisfaction.%目的探讨PDCA循环在硬膜外分娩镇痛质量管理中的应用。方法我们自2013年6月至2014年1月将PDCA循环应用于硬膜外分娩镇痛管理,进行现状调查分析,采用计划、执行、检查、处理循环,寻找硬膜外分娩镇痛中存在的问题并进行持续质量改进。结果与施行PDCA循环前(2013年4~5月)相比,施行PDCA循环后硬膜外分娩镇痛质量改进明显,疼痛有效控制率、镇痛满意度评分及产妇满意度均明显提高(P<0.05)。结论 PDCA循环应用于分娩镇痛质量管理,可较好地提高镇痛效果和产妇满意度。

  2. Effects of amiodarone and thoracic epidural analgesia on atrial fibrillation after coronary artery bypass grafting

    DEFF Research Database (Denmark)

    Nygård, Eigil; Sørensen, Lars H; Hviid, Lamia B;

    2004-01-01

    OBJECTIVE: This study was designed to assess the effects of a perioperative dosing regimen of amiodarone administration, high thoracic epidural anesthesia (TEA), or a combination of the 2 regimens on atrial fibrillation (AF) after coronary artery bypass grafting (CABG). DESIGN AND SETTING......: The study was prospective, controlled, and randomized and was performed in a tertiary health care center associated with a university. PARTICIPANTS: One hundred sixty-three patients scheduled for coronary artery bypass graft surgery. INTERVENTIONS: In this 2 x 2 factorial-designed study the patients were...... randomized to 1 of 4 regimens in which group E had perioperative TEA, group E+A had TEA and amiodarone, group A had amiodarone, and group C served as control. The epidural catheter was inserted at T1-3 the day before surgery. TEA groups received TEA for 96 hours. The amiodarone regimen consisted of a single...

  3. A Comparison of Intrathecal and Epidural Analgesia and Its Effect on Length of Labor

    Science.gov (United States)

    2013-01-31

    SCIENCES October 1997 (vi) DEDICATION I dedicate the creation of this thesis to my mother, my father, and my husband. To my mother, a Registered...sensitivity produced by a local anesthetic injection into the nerve sheath or tissues. Opioids: Chemical substances which are either endogenous or...utilization of lumbar epidural pain control for labor and delivery at a much lower price. Cost effective in terms of man-hours, money , and 13 the

  4. Epidural anaesthesia and analgesia - effects on surgical stress responses and implications for postoperative nutrition

    DEFF Research Database (Denmark)

    Holte, Kathrine; Kehlet, H

    2002-01-01

    BACKGROUND: Surgical injury leads to an endocrine-metabolic and inflammatory response with protein catabolism, increased cardiovascular demands, impaired pulmonary function and paralytic ileus, the most important release mechanisms being afferent neural stimuli and inflammatory mediators. RESULTS......: Epidural local anaesthetic blockade of afferent stimuli reduces endocrine metabolic responses, and improve postoperative catabolism. Furthermore, dynamic pain relief is achieved with improved pulmonary function and a pronounced reduction of postoperative ileus, thereby providing optimal conditions...

  5. The effects of different epidural analgesia formulas on labor and mode of delivery in nulliparous women

    Directory of Open Access Journals (Sweden)

    Shin-Yan Chen

    2014-03-01

    Conclusion: The C/S rate was higher in Groups C and D; however, the instrumental delivery rate was lower in Groups A and C. We conclude that PCEA with 1 mg/mL ropivacaine might provide the greatest benefit for labor analgesia.

  6. COMPARISON OF EFFECT OF MAGNESIUM SULPHATE AND PRESERVATIVE-FREE KETAMINE AS AN ADJUNCT TO EPIDURAL BUPIVACAINE FOR POSTOPERATIVE ANALGESIA IN ABDOMINAL HYSTERECTOMY

    Directory of Open Access Journals (Sweden)

    Radha Korumbil Raghavan

    2017-08-01

    Full Text Available BACKGROUND Neuraxial blocks are the most common method of anaesthesia in abdominal hysterectomies and epidural technique has been used widely to provide both anaesthesia and postoperative analgesia. It has become a common practice to use polypharmacy approach for treatment of intra and postoperative pain, because no drug has yet been identified that specifically inhibit nociception without side effects. The aim of the study is to compare the effects of magnesium sulphate versus preservative-free ketamine as an adjunct to epidural bupivacaine for postoperative analgesia in abdominal hysterectomy. MATERIALS AND METHODS After obtaining informed consent, the patients were divided into 3 groups of 40 each to receive 20 mL 0.5% bupivacaine (group B, 19 mL 0.5% bupivacaine + 50 mg magnesium sulphate (group BM, 19 mL 0.5% bupivacaine + 50 mg preservative-free ketamine (group BK. Epidural catheter was inserted at L1-L2 space using standard technique. Correct placement was confirmed by a test dose of 2% lignocaine + adrenaline 1 in 2 lakhs. Postoperative analgesia were assessed by VAS score and 0.125% bupivacaine infusion and 1 g paracetamol IV infusion was given as rescue analgesics when VAS ≥4. Onset duration, motor block and side effects were also monitored. RESULTS Mean time of duration of onset in group B, BM, BK were 20, 14, 18 minutes, respectively. Mean time for rescue analgesia were 180, 240 and 480 minutes in group 1, 2 and 3, respectively. These differences were statistically significant. The side effects noticed in each group were not statistically significant. CONCLUSION The onset of effect is faster when magnesium sulphate were added as an adjunct to bupivacaine as compared to preservativefree ketamine. The postoperative analgesia is found to be more with preservative-free ketamine as compared to magnesium sulphate without any significant side effects.

  7. Embolia amniótica durante parto normal sob analgesia: relato de caso

    Directory of Open Access Journals (Sweden)

    José Fernando Amaral Meletti

    2008-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A embolia amniótica é rara, sendo quadro clínico de início súbito e elevada morbidade. O objetivo deste trabalho foi apresentar um caso de embolia amniótica em paciente primigesta, submetida à analgesia para parto normal. RELATO DO CASO: Gestante de 38 anos, bolsa rota e 5 cm de dilatação do colo uterino. Apresentava-se com muita dor, agitação, sudorese, taquissistolia e venóclise com Ringer com lactato associado a 5 UI de ocitocina em gotejamento lento, pressão arterial (PA de 110 × 70 mmHg, freqüência cardíaca (FC 115 bpm, em ritmo sinusal e SpO2 de 98%. Optou-se por técnica combinada, empregando-se 2,5 mg de bupivacaína pesada e 20 µg de fentanil no espaço subaracnóideo e cateter no espaço peridural. Após 20 minutos do início da analgesia a paciente referiu prurido súbito e intenso, apresentou agitação, vômito e palidez, FC 160 bpm, taquipnéia, SpO2 80% e PA inaudível. Administrou-se solução fisiológica a 0,9% (500 mL associada à hidrocortisona, efedrina (50 mg e oxigênio sob máscara facial com fluxo de 10 L.min-1. Nesse momento, a PA era 60 × 30 mmHg, a FC 150 bpm e a SpO2 92%. Como a PA tendia a diminuir, foi administrado um total de 7 mg de metaraminol, divididos em várias doses. Após o parto vaginal, a paciente foi encaminhada à UTI com PA 90 × 60 mmHg, FC 110 bpm e taquipnéia. Duas horas após apresentou sangramento e hipotensão arterial, sendo diagnosticado coagulação intravascular disseminada (CIVD, tratada com cristalóides, concentrado de hemácias e plasma fresco congelado. Alta da UTI no terceiro dia de pós-operatório. CONCLUSÕES: Em decorrência da dramaticidade, gravidade e instalação abrupta do quadro, a rapidez e objetividade de medidas para manter sinais vitais são fundamentais e decisivos para a sobrevida das gestantes. Alerta-se para a importância de monitoração durante a analgesia de parto.

  8. COMPARISON OF EPIDURAL ANESTHESIA AND POSTOPERATIVE ANALGESIA WITH ROPIVACAINE AND FENTANYL IN OFF - PUMP CORONARY ARTERY BYPASS GRAFTING: A RANDOMIZED, CONTROLLED STUDY

    Directory of Open Access Journals (Sweden)

    Kaushal

    2014-01-01

    Full Text Available BACKGROUND: Our aim was to assess the efficacy of thoracic epidural anesthesia followed by postoperative epidural infusion with ropivacaine and Fentanyl in off - pump coronary bypass grafting. INTRODUCTION : In cardiosurgical patients, high thoracic epidural anesthesia (EA with local anesthetics and opioids can provide effective analgesia and reduce the number of perioperative complications. However, the use of EA in coronary surgery is controversial, and it is still unclear whether EA influences lung fluid balance , cardiopulmonary function and clinical outcome in OPCAB. Thus, the method requires further evaluation and its potential benefits in coronary patients should be weighed against its risks. MATERIALS AND METHODS : A prospective study was performed in 4 0 patients undergoing coronary artery bypass surgery who received high thoracic epidural analgesia. Group 1 received thoracic epidural 0.2% ropivacaine (bolus 10 ml, 10 min before starting surgery while group 2 pts. received Fentanyl 2 mcg/ml (bolus 10 ml , 10 min before starting surgery, then rate of epidural infusion adjusted between 3 - 8 ml/ hr. of the same concentration according to response. The Regimens aimed at a visual analog scale (VAS score < or = 4/10 . Hemodynamic parameters and blood gases were measured from extubation till 24 h after OPCAB. RESULTS : O utcome measures included the incidence of Visual Analogue Score (VAS < or =4/10, infusion rate adjustments and side - effects. Patients receiving ropivacaine were less likely to experience pain < or =4/10 (P' = 0.002; the infusion rate was lower (P' = 0.024; required less rate adjustments (P' = 0.001; a less need for noradrenaline (P' = 0.001 and antiemetic drugs (P' = 0.001. There were no significant differences between the groups for sedation s cores or the incidence of respiratory depression. CONCLUSION : This study suggests that ropivacaine 0.2% may be superior to fentanyl 2 microg/ml. We found a reduced number of

  9. Hematoma epidural espinal espontâneo durante a gravidez: registro de um caso

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    Ivan Hack

    1984-03-01

    Full Text Available Registro de caso de paciente no oitavo mês de gestação que desenvolveu hematoma epidural espinal espontâneo dorsolombar. A gravidez, determinando aumento da pressão intra-abdominal e, como consequência, aumento da pressão venosa no plexo epidural, poderia ter sido o fator desencadeante no hematoma- A paciente foi submetida a cirurgia precocemente, porém não apresentou recuperação do déficit sensitivo-motor. São discutidos aspectos clínicos, do tratamento cirúrgico, da evolução e da etiologia dos hematomas epidurals espinais espontâneos.

  10. Analgesia pós-toracotomia com associação de morfina por via peridural e venosa Analgesia pós-toracotomia con asociación de morfina por vía peridural y venosa Comparison of intravenous and epidural morphine analgesia after thoracotomy

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    Neuber Martins Fonseca

    2002-09-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Analgesia após cirurgia de tórax é feita por diferentes métodos. O objetivo do estudo foi avaliar a analgesia pós-operatória com associação de morfina por via venosa e peridural, comparada ao uso por via isolada. MÉTODO: Foram estudados 20 pacientes submetidos à cirurgia de tórax, ambos os sexos, estado físico ASA I a III. Foi feita medicação pré-anestésica com midazolam por via venosa (3 a 3,5 mg na SO. A monitorização constou de ECG contínuo, pressão arterial invasiva, oximetria de pulso, capnografia, PVC, diurese e temperatura. Primeiramente foi realizada anestesia peridural contínua, T7-T8 com 10 ml de bupivacaína a 0,25% e, em seguida, indução com fentanil (5 µg.kg-1, etomidato (0,2 a 0,3 mg.kg-1 e succinilcolina (1 mg.kg-1. Foi feita IOT com tubo de duplo lume, complementação com pancurônio (0,08 a 0,1 mg.kg-1 e ventilação controlada mecânica. Os pacientes foram então distribuídos aleatoriamente em três grupos. Ao Grupo I, administrou-se pelo cateter peridural, 2 mg de morfina 0,1% na indução da anestesia (M1, após 12 horas (M2 e 24 horas (M3 do final da cirurgia, ao Grupo II, morfina por via venosa em bomba de infusão (15 µg.kg.h-1 precedida de bolus de 50 µg.kg-1, durante 30 horas e ao Grupo III, morfina por via peridural na dose de 0,5 mg em M1, M2 e M3, associada com morfina venosa em bomba de infusão (8 µg.kg.h-1 precedida de bolus de 25 µg.kg-1, por 30 horas. Análise de gases arteriais, freqüências cardíaca e respiratória, presença de prurido, náuseas, vômitos e analgesia pós-operatória foram avaliados a cada 6 horas, até um total de 30 horas do pós-operatório. A analgesia foi avaliada por escala de graduação numérica (EGN de 0 a 10. RESULTADOS: A EGN apresentou redução no grupo I apenas no momento M2 não ocorrendo nos demais intervalos. Nos grupos II e III ocorreu redução da dor a partir de 18 horas em relação aos valores iniciais e em rela

  11. COMBINED SPINAL EPIDURAL ANALGESIA IN LABOUR: COMPARISON OF BUPIVACAINE 1.25 MG WITH FENTANYL AND ROPIVACAINE 2.5 MG WITH FENTANYL INTRATHECAL

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    Prakash T. S. N

    2016-10-01

    , 105 and 120 mins., i.e. (every 5 mins. for 15 mins. and then every 15 mins. for 2 hrs. until the next request for analgesia. After positioning the patient in supine position, onset of analgesia and dermatome level were checked by loss of sensation to pinprick, time of onset and degree of motor blockade was checked by Bromage classification. VAS pain scores for all patients immediately before and after 15 mins. of the procedure at the next request for analgesia. Vitals were recorded and study was terminated. Continuation of epidural analgesia was done with 0.125% bupivacaine + 2 µg fentanyl in 10 mL. Monitoring - mother’s vital parameters, progress of labour, efficacy of analgesia and foetal welfare were watched in coordination with attending obstetrician. Pulse, NIBP, SpO2, respiratory rate were recorded before and after the start of procedure and every 5 mins. for first 15 mins. and then every 15 mins. for 2 hrs. If bradycardia occurred at any time (<60 bts./mins., Inj. Glycopyrrolate 0.2 mg was given. If hypotension occurred, then it was treated appropriately with IV fluids and vasopressor. If pruritus occurred, it was treated with pheniramine. Sensory blockade assessed by pinprick and motor blockade was assessed by Bromage scale. Statistical Analysis- In the present study, results are given as mean±standard deviation and range values for continuous data. Students test was used to compare the two groups, categorical data are expressed as number and percentages and difference between the groups was compared by chi-square test. A p value of 0.05 or less was set for statistical significance.RESULTS Maternal hypotension of 15% was noted in both groups, which was statistically significant. Onset of sensory analgesia in seconds showed a standard deviation of 38.12 with a mean difference of 47 seconds between the two groups was found to be statistically highly significant with a p value of <0.001. Maximal dermatomal level of sensory block achieved also showed

  12. Comparison of local infiltration and epidural analgesia for postoperative pain control in total knee arthroplasty and total hip arthroplasty: A systematic review and meta-analysis

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    Huan Yan

    2016-11-01

    Full Text Available Pain management after total knee arthroplasty (TKA and total hip arthroplasty should permit early mobilization with minimal pain. Local infiltration analgesia (LIA is a new popular method for decreasing postoperative pain. The goal of this meta-analysis is to evaluate the efficacy of LIA in comparison with epidural analgesia. A literature search was performed in PubMed, EMBASE, the OVID database, Web of Science, and the Cochrane Library databases. The risk of bias was assessed using the Cochrane collaboration tool. Outcomes of interest included visual analog scale score, range of flexion, length of stay, and complications. Nine trials involving 537 patients met the inclusion criteria. LIA provides better pain relief and larger range of motion in TKA patients compared to epidural analgesia at the late postoperative period. No significant difference was observed in regard to the length of stay and complications. The current evidence shows that the use of local infiltration is effective for postoperative pain management in TKA patients. More high-quality randomized controlled trials with long-term follow-up are required for examining the long-term efficacy and safety of local infiltration. 

  13. The influence of epidural analgesia on platelet function and correlation with plasma bupivacaine concentrations.

    Science.gov (United States)

    Odoom, J A; Dokter, P W; Sturk, A; Ten Cate, J W; Sih, I L; Bovill, J G

    1988-09-01

    The effect of epidural anaesthesia with bupivacaine 0.5% on platelet aggregation was studied in seven patients undergoing transurethral resection of the prostate. Peak plasma concentrations of bupivacaine 470 +/- 270 ng ml-1 occurred at 30 min after administration. At that time there were no significant changes in platelet aggregation. However, the maximum rate of the primary- and secondary-aggregation velocities induced by 1.0 microM ADP were significantly decreased at 1 h and 3 h after bupivacaine administration. The maximum percentage ADP-induced platelet aggregation was also decreased significantly at 1 h and 3 h. The minimum concentration of ADP required to induce secondary-phase platelet aggregation was significantly increased at 1 h but not at 3 h. There was a significant correlation between bupivacaine concentrations and all platelet aggregation parameters except the maximum ADP-induced aggregation. Platelet inhibition occurred at plasma bupivacaine concentrations that were considerably lower than those needed to produce similar inhibition in vitro.

  14. Estudo comparativo entre concentrações de bupivacaína a 0,125% e a 0,25% associada ao fentanil para analgesia de parto por via peridural Estudio comparativo entre concentraciones de bupivacaína a 0,125% y a 0,25% asociada al fentanil para analgesia de parto por vía peridural Comparison between 0.125% and 0.25% bupivacaine associated to fentanyl for epidural labor analgesia

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    Marcos Emanuel Wortmann Gomes

    2004-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A analgesia de parto tem a finalidade de diminuir ou até excluir o sofrimento materno durante o trabalho de parto, sendo considerada um método seguro e efetivo para o alívio da dor. O objetivo deste trabalho foi comparar duas concentrações de bupivacaína (0,25% e 0,125%, associada ao fentanil na analgesia de parto por via peridural, quanto à eficácia antálgica e o grau de bloqueio motor, e verificar a influência das diferentes concentrações utilizadas na duração do trabalho de parto, no bem estar do recém-nascido e na satisfação materna. MÉTODO: Neste estudo prospectivo e duplamente encoberto, 51 gestantes primíparas foram distribuídas aleatoriamente em dois grupos para receberem uma de duas concentrações de bupivacaína para indução de analgesia de parto (0,25% [n = 23] ou 0,125% [n = 28]. Para a mensuração da analgesia, foi utilizado a escala numérica de dor, e para a avaliação do bloqueio motor, a escala de Bromage. Para a comparação das médias, foi utilizado o teste t de Student, e, para a comparação das proporções, o teste Qui-quadrado, com p JUSTIFICATIVA Y OBJETIVOS: La analgesia de parto tiene la finalidad de disminuir, o hasta excluir el sufrimiento materno durante el trabajo de parto, siendo considerada un método seguro y efectivo para el alivio del dolor. El objetivo de este trabajo fue comparar dos concentraciones de bupivacaína (0,25% e 0,125%, asociada al fentanil en la analgesia de parto por vía peridural, cuanto a la eficacia antálgica y el grado de bloqueo motor, y verificar la influencia de las diferentes concentraciones utilizadas en la duración del trabajo de parto, en el bien estar del recién-nacido y en la satisfacción materna. MÉTODO: En este estudio prospectivo y duplamente encubierto, 51 gestantes primíparas fueron distribuidas aleatoriamente en dos grupos para recibir una de dos concentraciones de bupivacaína para inducción de analgesia de parto

  15. Postoperative pain and patient-controlled epidural analgesia-related adverse effects in young and elderly patients: a retrospective analysis of 2,435 patients

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    Koh JC

    2017-04-01

    Full Text Available Jae Chul Koh, Young Song, So Yeon Kim, Sooyeun Park, Seo Hee Ko, Dong Woo Han Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea Abstract: In this retrospective study, data of 2,435 patients who received fentanyl and ropivacaine-based patient-controlled epidural analgesia (PCEA for pain relief after elective surgery under general or spinal anesthesia were reviewed. Differences in postoperative pain, incidence of patient-controlled analgesia (PCA-related adverse effects, and risk factors for the need for rescue analgesics for 48 hours postsurgery in young (age 20–39 years and elderly (age ≥70 years patients were evaluated. Although there were no significant differences in postoperative pain intensity between the two groups until 6 hours postsurgery, younger patients experienced greater postoperative pain intensity compared with older patients 6–48 hours postsurgery. While younger patients exhibited greater incidence of numbness, motor weakness, and discontinuation of PCA postsurgery, elderly patients exhibited greater incidence of hypotension, nausea/vomiting, rescue analgesia, and antiemetic administration. Upon multivariate analysis, low fentanyl dosage and history of smoking were found to be associated with an increased need for rescue analgesia among younger patients, while physical status classification III/IV and thoracic surgery were associated with a decreased need for rescue analgesia among the elderly. Discontinuation of PCA was more frequent among younger patients than the elderly (18.5% vs 13.5%, P=0.001. Reasons for discontinuation of PCA among young and elderly patients, respectively, were nausea and vomiting (6.8% vs 26.6%, numbness or motor weakness (67.8% vs 11.5%, urinary retention (7.4% vs 8.7%, dizziness (2.2% vs 5.2%, and hypotension (3.1% vs 20.3%. In conclusion, PCEA was more frequently associated with numbness, motor

  16. COMPA RATIVE EVALUATION OF INTRATHECAL, EPIDURAL AND INTRAVENOUS BOLUS SUFENTANIL FOR POST OPERATIVE ANALGESIA IN LOWER LIMB SURGERY

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    Sudhakar

    2015-06-01

    Full Text Available In clinical experience sufentanil is more effective when given epidurally than intrathecally and intravenously. To test this hypothesis we compare the analgesic characteristic of 10μgm of epidural, intrathecal and intravenous single shot sufenta nil for pain relieve after elective lower limb surgeries. A randomized double blind trial was conducted on 60 patients who were under - going elective lower limb surgery in epidural anesthesia with bupivacaine. In recovery room as soon as pain score higher than 3 on the scale of 10 on visual analogue score was reported 10μgm intravenous, intrathecal and epidural was given respectively. We concluded that epidural sufentanil is better as compared to intrathecal and intravenous in terms of duration of pain reli ef, vital complications and side effects for post - operative pain relief.

  17. Thoracic epidural analgesia in obese patients with body mass index of more than 30 kg/m 2 for off pump coronary artery bypass surgery

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    Sharma Munish

    2010-01-01

    Full Text Available Perioperative Thoracic epidural analgesia (TEA is an important part of a multimodal approach to improve analgesia and patient outcome after cardiac and thoracic surgery. This is particularly important for obese patients undergoing off pump coronary artery bypass surgery (OPCAB. We conducted a randomized clinical trial at tertiary care cardiac institute to compare the effect of TEA and conventional opioid based analgesia on perioperative lung functions and pain scores in obese patients undergoing OPCAB. Sixty obese patients with body mass index> 30 kg/m 2 for elective OPCAB were randomized into two groups (n=30 each. Patients in both the groups received general anesthesia but in group 1, TEA was also administered. We performed spirometry as preoperative assessment and at six hours, 24 hours, second, third, fourth and fifth day after extubation, along with arterial blood gases analysis. Visual analogue scale at rest and on coughing was recorded to assess the degree of analgesia. The other parameters observed were: time to endotracheal extubation, oxygen withdrawal time and intensive care unit length of stay. On statistical analysis there was a significant difference in Vital Capacity at six hours, 24 hours, second and third day postextubation. Forced vital capacity and forced expiratory volume in one second followed the same pattern for first four postoperative days and peak expiratory flow rate remained statistically high till second postoperative day. ABG values and PaO 2 /FiO 2 ratio were statistically higher in the study group up to five days. Visual analogue scale at rest and on coughing was significantly lower till fourth and third postoperative day respectively. Tracheal extubation time, oxygen withdrawal time and ICU stay were significantly less in group 1. The use of TEA resulted in better analgesia, early tracheal extubation and shorter ICU stay and should be considered for obese patients undergoing OPCAB.

  18. Analgesia peridural contínua: análise da eficácia, efeitos adversos e fatores de risco para ocorrência de complicações Analgesia peridural continua: análisis de la eficacia, efectos adversos y factores de riesgo para ocurrencia de complicaciones Continuous epidural analgesia: analysis of efficacy, side effects and risk factors

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    Leonardo Teixeira Domingues Duarte

    2004-06-01

    ,1%, 92,8% y 93,3% de la población estudiada. CONCLUSIONES: La analgesia peridural continua es efectiva y segura. Las complicaciones ocurridas no fueron consideradas graves. Todavía, no se puede dispensar rigurosa vigilancia a fin de obtenerse analgesia satisfactoria y diminuir las complicaciones.BACKGROUND AND OBJECTIVES: Epidural analgesia with local anesthetics and opioids has a reputation of high efficacy with low incidence of side effects. This study aimed at determining incidence, type and severity of postoperative complications related to epidural analgesia and catheter insertion. METHODS: Participated in this retrospective study 469 patients submitted to postoperative epidural analgesia in the period 10/18/99 to 10/18/01. Epidural analgesia was induced with 0.1% bupivacaine and fentanyl (1 to 5 µg.mL-1, at a 3 mL.h-1 rate. Infusion rate was adjusted according to patients' pain complaint. The following variables were evaluated: epidural infusion duration; incidence of side-effects and complications related to demographics, type of surgery and epidural catheter position; and quality of analgesia by means of a pain visual analog scale and a patients' satisfaction index. RESULTS: Epidural catheters remained in place 2.2 days in average, varying from 6 to 10 days. Global rate of technique-related complications was 46.3%, most of them minor complications without clinical repercussion. From these, 13.9% were directly related to the epidural catheter (disconnection, externalization, low back pain, inflammation and local infection. Other common complications were vomiting and urinary retention. Postoperative analgesia was effective in 97.2% of the patients which referred satisfaction with the technique. Patients without pain or slight pain during the first, second and third postoperative day represented 80.1%, 92.8% and 93.3%, respectively, of the studied population. CONCLUSIONS: Continuous epidural analgesia is effective and safe. Complications were not severe. However

  19. Research Progress in Epidural or Spinal Analgesia for Labor Pain%椎管内阻滞分娩镇痛的研究进展

    Institute of Scientific and Technical Information of China (English)

    余孔清

    2013-01-01

    With the development of medical technology,research on epidural or spinal analgesia for labor pain has become deeper and deeper. And it is a hot clinical research point in obstetrics. In recent years, researching in the field has developed from the approach of spinal blocking for labor analgesia to the commonly used drugs,and at last the influence on the maternal and child. Here is to make a review on the research status and development of spinal block for labor analgesia in accordance with the above three parts of contents.%随着医学技术的不断提高与进步,分娩镇痛的研究逐渐成为产科临床研究中的一个热点问题.近年来,该领域的研究越来越深入,由原来椎管内阻滞分娩镇痛方式的研究到椎管内阻滞分娩镇痛常用的药物,最后到椎管内阻滞分娩镇痛对母婴产生的影响.该文着重从上述三方面对椎管内阻滞分娩镇痛的研究现状及进展予以综述.

  20. Analgesia de parto: estudo comparativo entre anestesia combinada raquiperidural versus anestesia peridural contínua Analgesia de parto: estudio comparativo entre anestesia combinada raqui-peridural versus anestesia peridural continua Labor analgesia: a comparative study between combined spinal-epidural anesthesia versus continuous epidural anesthesia

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    Carlos Alberto de Figueiredo Côrtes

    2007-02-01

    proporcionado un rápido e inmediato alivio del dolor. Estudios clínicos con mayor número de casos son necesarios para evaluar diferencia en la incidencia de cesarianas.BACKGROUND AND OBJECTIVES: Pain relief during labor is a permanent concern, aiming at the maternal well being, decreasing the stress secondary to pain, and reducing its consequences on the fetus. Several analgesia techniques can be used during labor. The aim of this study was to compare continuous and combined epidural analgesia, both of them using 0.25% bupivacaine with 50% enantiomeric excess and fentanyl. METHODS: Forty pregnant women, in labor, with cervical dilation between 4 and 5 cm, were randomly divided in two groups. Group I received continuous epidural anesthesia. Group II received combined anesthesia. The following parameters were evaluated: anthropometric measurements, gestational age, cervical dilation, length of time between the blockade and absence of pain according to the visual analogic scale, ability to walk, length of time between analgesia and complete cervical dilation, duration of the expulsive phase, maternal hemodynamic parameters, and vitality of the newborn. Possible complications, such as respiratory depression, maternal hypotension, pruritus, nausea, and vomiting were also evaluated. The Student t test was used to compare the means and the Chi-square test was used to compare the number of pregnancies and type of labor. RESULTS: There were no statistically significant differences between both groups regarding the length of time between the beginning of analgesia and complete cervical dilation, as well as regarding the duration of the expulsive phase, incidence of cesarean section related to the analgesia, maternal hemodynamic parameters, and vitality of the newborn. CONCLUSIONS: Both techniques are effective and safe for labor analgesia, although the combined technique provided fast and immediate pain relief. Clinical studies with a larger number of patients are necessary to

  1. A STUDY COMPARING DIFFERENT CONCENTRATIONS OF ROPIVACAINE 0.125% VS. 0.2%, WHEN GIVEN WITH FENTANYL 2 MCG/ML FOR EPIDURAL LABOUR ANALGESIA

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    Vindhya K

    2017-07-01

    Full Text Available BACKGROUND Epidural administration of local anaesthetics, with or without opioids, is commonly used for the relief of pain in labor. Lower concentration of local anesthetics is used for providing labor epidural analgesia. MATERIALS AND METHODS After approval of the Institutional Ethical Committee, this study was conducted at a teaching hospital in GGH, Kakinada on 50 term parturients. 50 parturients of ASA I & II, primi or multi gravida with singleton pregnancy having vertex presentation were taken up for the study. They were randomly divided into 2 groups–Group R1 and Group R2 each comprising of 25 parturients. Study patients (n=50 were randomly assigned to one of two groups of 25 each. They received aliquots of epidural injection using either, 10 ml of ropivacaine 0.125 % with 2 μg/ml fentanyl (group R1 or 10 ml of ropivacaine 0.2% with 2 μg/ml fentanyl (group R2. RESULTS Demographic data, obstetric data, and injection delivery interval were comparable in both groups. Effective labor analgesia with no motor blockade was observed in both groups. Duration of analgesia after initial bolus dose was also significantly longer in group R2 (126.45 ± 12.34 min than in group R1 (73.05±27.4min. Ropivacaine at both concentrations (0.2% vs. 0.125% along with fentanyl 2μg / ml decreased visual analog scale (VAS scores to <3 in all parturients uniformly. Mean VAS scores were significantly less in group R2 than in group R1 at 5,60, and 90 min. Requirement of top-up doses was significantly less in group R2 as compared to group R1. Consumption of ropivacaine was comparable in both the groups (58.23 ± 5.48 mg in group R1 and 65.88 ± 6.29 mg in group R2, but consumption of fentanyl was significantly more in group R1 (94.31 ± 4.93 mg as compared to group R2 (31.58 ± 2.38 mg. There were no significant changes in haemodynamics, nor adverse effects related to neonatal or maternal outcomes in both groups. CONCLUSION We conclude that both the concentrations

  2. Application of the epidural anesthesia in labor analgesia%硬膜外麻醉在分娩镇痛中的应用

    Institute of Scientific and Technical Information of China (English)

    王娟; 王昌合; 曲珣

    2014-01-01

    Objective:To explore the clinical effects of the epidural anesthesia in labor analgesia,and its effects on stages of labor and pregnancy outcome of maternal and child. Methods:Two hundred and sixteen natural childbirth puerperas with vaginal delivery, full term,single fetus,vertex presentation and no pregnancy complications and anesthesia contraindications,were randomly divided into the observation group and control group. The labor analgesia in observation group and control group were treated with epidural block anesthesia and non-drug,respectively. The delivery pain,duration of second and third labor,postpartum hemorrhage and Apgar scoring of neonate in two groups were observed. Results:The degree of delivery pain in observation group was significantly lower than that in control group(P0. 05). Conclusions:The epidural anesthesia is an ideal method in labor analgesia, which can accelerate labor progress,and is safe and worthy of spreading.%目的:探讨硬膜外麻醉用于分娩镇痛的临床效果及对产程、母婴分娩结局的影响。方法:选取自然分娩的产妇216例,全部足月、单胎、头位,无妊娠并发症,无麻醉禁忌证,评估经阴道分娩无困难者,随机分为观察组和对照组各108例,观察组采用硬膜外麻醉分娩镇痛,对照组采用非药物性分娩镇痛。观察2组产妇分娩疼痛的程度、第二产程和第三产程时间、产后出血量及新生儿Apgar评分。结果:观察组产妇分娩期疼痛程度明显低于对照组(P0.05)。结论:硬膜外阻滞麻醉用于分娩镇痛是较为理想的方法,对母婴均有较高的安全性,可加速产程进展,值得推广。

  3. COMPARATIVE STUDY OF 0.0625% BUPIVACAINE WITH FENTANYL VERSUS 0.1% ROPIVACAINE WITH FENTANYL AS CONTINUOUS EPIDURAL INFUSION IN LABOUR ANALGESIA

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    L. Raghavan

    2016-07-01

    Full Text Available BACKGROUND We undertook this study to see whether ropivacaine offers any significant advantage over bupivacaine in our institutional practice with regards to obstetrical outcome and whether a changeover from bupivacaine to ropivacaine was warranted. This study compares the efficacy of Ropivacaine and Bupivacaine regarding pain relief, motor block and labour characteristics. AIM The objective of the current study is to compare the efficacy of equipotent doses of ropivacaine with fentanyl and bupivacaine with fentanyl as continuous infusion in labour epidural analgesia with respect to Quality of pain relief, Motor Block, Duration of labour, Mode of delivery - Spontaneous Vaginal/Assisted with forceps/Caesarean Section, Neonatal outcome – APGAR score, Complications if any. METHODS AND MATERIALS The study was a prospective randomized double blinded trial involving 60 parturients (30 in each group attending the Dept. of Obstetrics and Gynaecology, Chengalpattu Medical College Hospital. Informed consent was obtained. Detailed history of the patient was collected. Routine investigations were done as per our hospital labour protocol. Patients fulfilling the inclusion criteria and who gave consent were then randomly allocated to one of the study groups on the basis of computerized randomized list. STATISTICAL ANALYSIS The statistical analysis was done using SPSS version 16 for windows. The profiles of the cases were compared with the treatment allocation in order to check if there was any significant difference. Chi-square test for association was used to compare categorical variables between treatment allocations. RESULTS The observations of this study show that pain relief offered by epidural ropivacaine is as good and effective as epidural bupivacaine. Also the duration of labour, mode of delivery, neonatal outcome and complications are comparable between the two groups. CONCLUSION Findings suggest that the use of epidural ropivacaine for labour

  4. The Clinical Analysis of Using Ropivacaine in Epidural Analgesia%罗哌卡因用于硬膜外分娩镇痛的临床分析

    Institute of Scientific and Technical Information of China (English)

    朱红仙

    2015-01-01

    目的:探讨罗哌卡因硬膜外阻滞分娩镇痛的效果及对产妇、新生儿的影响。方法选择自愿行分娩镇痛的180例初产妇为观察组,采用0.15%罗哌卡因自控硬膜外分娩镇痛泵观察产妇疼痛程度、副作用、产程时间、分娩结局及新生儿情况,同期未行任何分娩镇痛的180例产妇为对照组进行对比。结果观察组患者i、Ⅱ、Ⅲ级疼痛率分别为72.22%、26.67%、1.11%,无Ⅳ级疼痛患者,而对照组上述各级疼痛率分别为11.67%、16.11%、26.11%、46.11%,观察组i、Ⅱ级疼痛率显著低于对照组,而Ⅲ、Ⅳ级疼痛率显著低于对照组,且两组差异有统计学意义(P0.05)。结论硬膜外注射罗哌卡因达到产时镇痛的目的,且减少麻醉药用量,无运动阻滞,不影响产程的进展与分娩结局,更适用于分娩的镇痛,必要时可延续至剖宫产麻醉,且降低剖宫产率。%ABSTRACT:Objective:to investigate ropivacaine epidural labor analgesia effect and the effects on maternal, newborn. Methods:to choose voluntary labor analgesia primipara 180 cases as the observation group, with 0.15%ropivacaine patient controlled epidural analgesia pump observed maternal side effects, the degree of pain, duration of labor, delivery and neonatal outcomes, 180 cases of pregnant women during the same period without any labor analgesia for the compare group. Results:in the observation group, i, ii, iii grade pain rates were 72.22%, 26.67%, 1.11%, and no grade iV patients with pain, while the control group, the levels of pain were respectively 11.67%, 16.11%, 26.11%, 46.11%, to observe the level ii pain rate group of i, signiifcantly lower than the control group, while the iii, iV pain rate signiifcantly lower than the control group, and there was a statistically signiifcant difference between the two groups (P0.05). Conclusion:epidural injection of ropivacaine to achieve the purpose of intrapartum analgesia, and reduce the

  5. Incidência de depressão respiratória no pós-operatório em pacientes submetidos à analgesia venosa ou peridural com opioides Incidencia de depresión respiratoria en el postoperatorio en pacientes sometidos a la analgesia venosa o epidural con opioides The incidence of postoperative respiratory depression in patients undergoing intravenous or epidural analgesia with opioids

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    Leonardo Teixeira Domingues Duarte

    2009-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A analgesia controlada pelo paciente (PCA, por via venosa ou peridural, é técnica segura e eficaz no tratamento da dor pós-operatória. Todavia, o uso de opioides não é isento de risco, e a depressão respiratória é a complicação mais temida. Os objetivos deste estudo foram descrever a incidência de depressão respiratória associada à analgesia pós-operatória com opioides administrados por via peridural ou venosa e as características dos pacientes que apresentaram a complicação. MÉTODO: Estudo de incidência, retrospectivo, em pacientes operados no Hospital SARAH Brasília entre dezembro de 1999 e dezembro de 2007 e tratados com PCA com opioides por via venosa ou peridural. Foram definidos como casos de depressão respiratória: frequência respiratória JUSTIFICATIVA Y OBJETIVOS: La analgesia controlada por el paciente (PCA, por vía venosa o epidural, es una técnica segura y eficaz en el tratamiento del dolor postoperatorio. Sin embargo, el uso de opioides no está exento de riesgos y la depresión respiratoria es la complicación más temida. Los objetivos de este estudio fueron describir la incidencia de depresión respiratoria asociada a la analgesia postoperatoria con opioides administrados por vía epidural o venosa, y las características de los pacientes que presentaron la complicación. MÉTODO: Estudio de incidencia retrospectiva en pacientes operados en el Hospital SARAH Brasília entre diciembre de 1999 y diciembre de 2007 y tratados con PCA con opioides por vía venosa o epidural. Se definieron como casos de depresión respiratoria, frecuencia respiratoria d" 8 irpm, necesidad del uso de naloxona, o saturación periférica de oxígeno por debajo de un 90%. RESULTADOS: Fueron evaluados 2790 pacientes, de los cuales 635 pacientes recibieron PCA venosa y 2155, analgesia epidural. Se dieron siete casos de depresión respiratoria postoperatoria (incidencia de 0,25%. De ellos, seis pacientes

  6. Clinical analysis on continuous epidural labor analgesia in 224 cases%224例连续硬膜外分娩镇痛临床分析

    Institute of Scientific and Technical Information of China (English)

    李思会; 高启俊

    2014-01-01

    Objective To explore the effect of continuous epidural labor analgesia and its impact on pregnancy outcome. Method A to-tal of 224 primiparous women receiving continuous epidural labor analgesia voluntarily were selected as study group;250 primiparous women not receiving continuous epidural labor analgesia during the same period were randomly selected as control group;the analgesic effects and pregnancy outcomes in the two groups were compared. Results VAS score in study group was significantly lower than that in control group;the incidence rate of uterine inertia during stages of labor in study group was significantly higher than that in control group;the duration time of the first stage of labor,the duration time of the second stage of labor,the total duration time of stages of labor in study group were signifi-cantly higher than those in control group;the rate of lateral episiotomy in study group was significantly lower than that in control group,there were statistically significant differences in the above-mentioned indexes between the two groups( P﹤0. 005 );there was no statistically significant difference in the incidence rates of cesarean section,surgical midwifery,postpartum hemorrhage,and neonatal asphyxia between the two groups(P>0. 05). Conclusion The effect of continuous epidural labor analgesia is good,the method can reduce the harms of deliv-ery to pregnant women and their babies,the safety is high,so the method is worthy to be popularized extensively.%目的:探讨连续硬膜外分娩镇痛的镇痛效果及对妊娠结局的影响。方法:选取自愿接受并实行连续硬膜外分娩镇痛的224例初产妇为研究组,随机选取同期不采用分娩镇痛的初产妇250例为对照组,比较分析两组镇痛效果及妊娠结局。结果:镇痛组的视觉模拟标尺( VAS)法评分明显低于对照组,产程中宫缩乏力的发生率高于对照组,的第一产程、第二产程、总产程时长高于对照组,会

  7. A RANDOMIZED COMPARISON OF 0.125% LEVOBUPIVACAINE, 0.125% ROPIVACAINE AND 0.125%BUPIVACAINE COMBINED WITH 2μG/ML FENTANYL FOR EPIDURAL LABOR ANALGESIA

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    Gopal Reddy

    2015-06-01

    Full Text Available The labor pain is one of the most severe pains that a woman could ever be suffered. Today, many medical and psychological methods are used in an effort to reduce labor pain. Epidural analgesia is the best current method used for the purposes of obstetric a nalgesia. OBJECTIVE: To compare analgesic efficacy and intensity of sensory block with continuous infusions of bupivacaine, levobupivacaine and ropivacaine for labor epidural analgesia. Design: Prospective, randomized, double - blind study. PATIENTS: 95 ASA physical status I and II, term, primigravida. Interventions: All patients received epidural labor analgesia. Epidural medication consisted of an initial bolus of 10 mL 0.125% local anesthetic combined with2μg/ml Fentanyl followed by an infusion at 10 ml/h of local anesthetic with2μg/ml Fentanyl . Patients were allocated to three groups, as follows: each group received bolus and infusion of 0.125%local anaesthetic group1 bupivacaine, group 2 levobupivacaine and group 3 ropivacaine respectively. MEASUREMENTS: Maternal vital signs, pain visual analog scale (VAS score, sensory levels, and motor block (Bromage score were recorded at intervals. Duration of first and second stage and mode of delivery were also recorded. CONCLUSION: All three regimens were effectiv e during first stage of labor although pain scores were higher in those receiving levobupivacaine and ropivacaine. Motor block was greater with bupivacaine than with levobupivacaine and ropivacaine.

  8. COMPARATIVE STUDY ON POST - OPERATIVE ANALGESIA IN LOWER LIMB ARTHROPLASTIES WITH CONTINUOUS EPIDURAL INFUSION OF 0.125% BUPIVACAINE AND TWO DIFFERENT NARCOTIC ANALGESICS FENTANYL AND SUFENTANIL

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    Rajeev

    2015-02-01

    Full Text Available Present study was carried out to compare and evaluate the effect of fentany and sufentanil in combination of bupivacaine on postoperative pain relief and possible side effects if any in patients operated for hip and knee arthroplasties. We randomly selected sixty patients of ASA grade I - III of age 18 to 75 years divided in to two groups. Group – I Received2.5 μg/ml fentanyl along with 0.125% bupivacaine as a continuous epidural infusion at the rate of 5 ml/hr up to 48 hr after the surgery. Group - II Received 0.25 μg/ml sufentanil along with 0.125% bupivacaine as a continuous epidural infusion at the rate of 5 ml/hr up to 48 hr after the surgery. Analgesia was assessed by Visual analogue scale and motor block if any by Bromage scale. Haemodynamics and respiratory parameters were recorded and side effects if any were noted. In group I mean VAS score during rest was 27.0 +/ - 4.8 and mean VAS score during movement was 33.5+/ - 4.9 in group II mean VAS score during rest was 20.8+/ - 4.9 and mean VAS score during movement was 27.7+/ - 5.2. T he dynamic pain VAS score showed a statistically significant difference between two groups . haemodynamics parameters were similar in both groups. Thus group II patients received sufentanil along with 0.125% bupivacaine had better post - operative analgesia d uring movement as well as at rest without respiratory depression or significant side effects.

  9. Efeitos da analgesia peridural e do bloqueio contínuo do plexo lombar sobre a reabilitação funcional após artroplastia total do quadril Efectos de la analgesia epidural y del bloqueo continuo del plexo lumbar sobre la rehabilitación funcional después de la artroplastia total de cadera Effects of epidural analgesia and continuous lumbar plexus block on functional rehabilitation after total hip arthroplasty

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    Leonardo Teixeira Domingues Duarte

    2009-10-01

    ésica eficaz y que permita la movilidad precoz, la participación en las actividades de rehabilitación, y una rápida recuperación funcional. El objetivo de este estudio, fue comparar los efectos de las técnicas de analgesia controlada por el paciente (ACP, por las vías epidural y perineural del plexo lumbar sobre la rehabilitación funcional en pacientes sometidos a la ATC. MÉTODO: Pacientes en estado físico ASA I a III, que fueron ubicados aleatoriamente en los grupos Epidural y Lumbar. Para la ATC, se realizó la anestesia epidural lumbar continua con ropivacaína a 0,5% (Epidural o bloqueo continuo del plexo lumbar con ropivacaína a 0,5% (Lumbar. En la sala de recuperación, se inició ACP con infusión de ropivacaína a 0,2% (Lumbar o ropivacaína a 0,2% + fentanil 3 µg.mL-1 (Epidural. La eficacia de la analgesia en las primeras 48 horas después de la ATC (niveles de dolor, consumo de morfina de rescate y de bolos de la bomba de ACP, se comparó entre los grupos. Los diferentes parámetros de la rehabilitación postoperatoria también se estudiaron. RESULTADOS: Cuarenta y un pacientes se sometieron al análisis estadístico. Los niveles de dolor en reposo fueron similares en los dos grupos. A pesar de un control más efectivo del dolor dinámico en el grupo Epidural y de un uso más potente de la morfina, que se aplicó más a menudo y precozmente en el grupo Lumbar, no hubo diferencia entre los grupos en ninguno de los parámetros estudiados de rehabilitación. Las técnicas de analgesia no influyeron en las fallas en el proceso de rehabilitación. CONCLUSIONES: El más alto nivel de efectividad de la analgesia epidural, no se tradujo en una mejoría en el proceso de rehabilitación, ni tampoco redujo el tiempo necesario para alcanzar los resultados estudiados.BAKGROUND AND OBJECTIVES: Pain after total hip arthroplasty (THA is severe and it is aggravated by movements, which requires an effective analgesic technique that allows early mobilization, participation

  10. Adjunct High Frequency Transcutaneous Electric Stimulation (TENS) for Postoperative Pain Management during Weaning from Epidural Analgesia Following Colon Surgery: Results from a Controlled Pilot Study.

    Science.gov (United States)

    Bjerså, Kristofer; Jildenstaal, Pether; Jakobsson, Jan; Egardt, Madelene; Fagevik Olsén, Monika

    2015-12-01

    The potential benefit of nonpharmacological adjunctive therapy is not well-studied following major abdominal surgery. The aim of the present study was to investigate transcutaneous electrical nerve stimulation (TENS) as a complementary nonpharmacological analgesia intervention during weaning from epidural analgesia (EDA) after open lower abdominal surgery. Patients were randomized to TENS and sham TENS during weaning from EDA. The effects on pain at rest, following short walk, and after deep breath were assessed by visual analog scale (VAS) grading. Number of patients assessed was lower than calculated because of change in clinical routine. Pain scores overall were low. A trend of lower pain scores was observed in the active TENS group of patients; a statistical significance between the groups was found for the pain lying prone in bed (p TENS use in postoperative pain management during weaning from EDA after open colon surgery. Further studies are warranted in order to verify the potential beneficial effects from TENS during weaning from EDA after open, lower abdominal surgery.

  11. Effectiveness of Epidural Analgesia, Continuous Surgical Site Analgesia, and Patient-Controlled Analgesic Morphine for Postoperative Pain Management and Hyperalgesia, Rehabilitation, and Health-Related Quality of Life After Open Nephrectomy: A Prospective, Randomized, Controlled Study.

    Science.gov (United States)

    Capdevila, Xavier; Moulard, Sebastien; Plasse, Christian; Peshaud, Jean-Luc; Molinari, Nicolas; Dadure, Christophe; Bringuier, Sophie

    2017-01-01

    There is no widely recognized effective technique to optimally reduce pain scores and prevent persistent postoperative pain after nephrectomy. We compared continuous surgical site analgesia (CSSA), epidural analgesia (EA), and a control group (patient-controlled analgesic morphine) in patients undergoing open nephrectomy. Sixty consecutive patients were randomized to be part of EA, CSSA, or control groups postoperatively for 72 hours. All patients received patient-controlled analgesic morphine, if needed. Hyperalgesia was assessed on the first, second, and third postoperative days. Chronic pain characteristics and quality of life were analyzed at 1 and 3 months. The primary outcome was the pain score at 24 hours. Secondary outcomes were morphine consumption, postoperative rehabilitation, hyperalgesia, chronic pain incidence, and quality-of-life parameters. At 24 hours, mean ± standard deviation pain values at rest (2.4 ± 1.7, 2.2 ± 1.2, and 4.2 ± 1.2, respectively, in EA, CSSA, and control groups, P control group. Rehabilitation parameters improved sooner in the EA and CSSA groups. Median values of area of hyperalgesia differed at 48 hours between the EA group and the control group (36.4 cm) and (52 cm) (P = .01) and at 72 hours among the EA group, CSSA group, and the control group (40 cm, 39.5 cm, and 59 cm, respectively; P = .002). CSSA reduced the severity of pain and hyperalgesia at 1 month and optimized quality of life 3 months after surgery (role physical scores, P = .005). CSSA and EA significantly improve postoperative analgesia, reduce postoperative morphine consumption, area of wound hyperalgesia, and accelerate patient rehabilitation after open nephrectomy. CSSA significantly reduces the severity of residual pain 1 month after surgery and optimizes quality-of-life parameters 3 months after surgery.

  12. Epidural analgesia during open radical prostatectomy does not improve long-term cancer-related outcome: a retrospective study in patients with advanced prostate cancer.

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    Patrick Y Wuethrich

    Full Text Available BACKGROUND: A beneficial effect of regional anesthesia on cancer related outcome in various solid tumors has been proposed. The data on prostate cancer is conflicting and reports on long-term cancer specific survival are lacking. METHODS: In a retrospective, single-center study, outcomes of 148 consecutive patients with locally advanced prostate cancer pT3/4 who underwent retropubic radical prostatectomy (RRP with general anesthesia combined with intra- and postoperative epidural analgesia (n=67 or with postoperative ketorolac-morphine analgesia (n=81 were reviewed. The median observation time was 14.00 years (range 10.87-17.75 yrs. Biochemical recurrence (BCR-free, local and distant recurrence-free, cancer-specific, and overall survival were estimated using the Kaplan-Meier technique. Multivariate Cox proportional-hazards regression models were used to analyze clinicopathologic variables associated with disease progression and death. RESULTS: The survival estimates for BCR-free, local and distant recurrence-free, cancer-specific survival and overall survival did not differ between the two groups (P=0.64, P=0.75, P=0.18, P=0.32 and P=0.07. For both groups, higher preoperative PSA (hazard ratio (HR 1.02, 95% confidence interval (CI 1.01-1.02, P<0.0001, increased specimen Gleason score (HR 1.24, 95% CI 1.06-1.46, P=0.007 and positive nodal status (HR 1.66, 95% CI 1.03-2.67, P=0.04 were associated with higher risk of BCR. Increased specimen Gleason score predicted death from prostate cancer (HR 2.46, 95% CI 1.65-3.68, P<0.0001. CONCLUSIONS: General anaesthesia combined with epidural analgesia did not reduce the risk of cancer progression or improve survival after RRP for prostate cancer in this group of patients at high risk for disease progression with a median observation time of 14.00 yrs.

  13. The roles of acute and chronic pain in regression of sensory analgesia during continuous epidural bupivacaine infusion

    DEFF Research Database (Denmark)

    Mogensen, T; Scott, N B; Lund, Claus

    1988-01-01

    -point scale) were assessed hourly for 16 hours during continuous epidural infusion of 0.5% plain bupivacaine (8 ml/hr) in 12 patients with chronic nonsurgical pain and in 30 patients after major abdominal surgery performed under combined bupivacaine and halothane--N2O general anesthesia. No opiates were given...

  14. The roles of acute and chronic pain in regression of sensory analgesia during continuous epidural bupivacaine infusion

    DEFF Research Database (Denmark)

    Mogensen, T; Scott, N B; Lund, Claus;

    1988-01-01

    -point scale) were assessed hourly for 16 hours during continuous epidural infusion of 0.5% plain bupivacaine (8 ml/hr) in 12 patients with chronic nonsurgical pain and in 30 patients after major abdominal surgery performed under combined bupivacaine and halothane--N2O general anesthesia. No opiates were given...

  15. The effects of adding epinephrine or xylazine to lidocaine solution for lumbosacral epidural analgesia in fat-tailed sheep

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    Maryam Rostami

    2012-04-01

    Full Text Available This blinded, randomised experimental study was designed to compare the analgesic effects of lumbosacral epidural administration of lidocaine-epinephrine or lidocaine-xylazine combinations in fat-tailed sheep. Nine healthy fat-tailed male lambs (mean ± s.d. age, 4.6 ± 0.4 months; weight, 24.6 kg ± 2.5 kg were randomly allocated into four groups of six sheep: lidocaine 2% (LID, lidocaine-epinephrine 5 µg/mL (LIDEP, lidocaine-xylazine 0.05 mg/kg (LIDXY or bupivacaine 0.5% (BUP. The onset and duration of flank, perineum and hindlimb anaesthesia and the onset and duration of hindlimb paralysis were recorded. Epidural administration of LID, LIDEP, LIDXY or BUP produced anaesthesia within 6.6 min, 7.6 min, 3.4 min and 8.4 min, respectively. The mean onset of anaesthesia in the LIDXY group was significantly shorter compared with the BUP group (p = 0.02. The mean duration of anaesthesia was 107.9 min, 190.4 min, 147.6 min and 169.7 min for LID, LIDEP, LIDXY and BUP, respectively. The onset of hindlimb paralysis was faster in the LIDXY group than in the BUP group; however, the duration of hindlimb paralysis was shorter in LIDXY compared with LIDEP. Epidural administration of LIDEP or LIDXY provides a comparable duration of local anaesthesia without any adverse effects in fat-tailed sheep. Epidural LIDXY did not appear to be advantageous over epidural LIDEP.

  16. Clinical observation of epidural analgesia for labor pain in 428 cases%硬膜外阻滞镇痛应用于分娩镇痛428例的临床研究

    Institute of Scientific and Technical Information of China (English)

    谢尧; 江露; 王琳; 常青

    2012-01-01

    Objective To study the safty,effectiveness of epidural analgesia for labor pain and its influence on the labor course, and patients. Methods The clinic data from Nov. 2010 to Apr. 2011 were analysed to detect the differences between the epidural analgesia group and non-epidural analgesia group on labor course, delivery mode, incidence of postpartum hemorrhage, neonatal asphyxia. Results The epidural analgesia group had a prolonged latency and higher incidence of cesarean saction,but lower incidence of perineal laceration(P0. 05). Conclusion Eepidural analgesia for labor pain is safe, effective,and harmless for patients. It is worth popularizing. But more research were needed to find whether the epidural analgesia prolonged latency and make higher incidence of cesarean saction.%目的 探讨分娩镇痛的安全性、效果及对产程、母婴的影响.方法 回顾本院2010年11月至2011年4月采用硬膜外给药方式行分娩镇痛病例428例与同期未行分娩镇痛病例111例对比,观察镇痛效果、产程时间、分娩方式、产后出血的情况,以及会阴裂伤及新生儿窒息发生率.结果 行分娩镇痛组与未行分娩镇痛组比较,镇痛效果确切,分娩镇痛组潜伏期延长,会阴裂伤发生率降低(P0.05).对剖宫产率是否增高的影响尚不明确.结论 硬膜外镇痛的使用安全有效,对母婴无明显不良影响,值得推广.其是否延长产程、提高剖宫产率尚需进一步研究.

  17. Comparative evaluation of continuous intercostal nerve block or epidural analgesia on the rate of respiratory complications, intensive care unit, and hospital stay following traumatic rib fractures: a retrospective review

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    Britt T

    2015-10-01

    Full Text Available Todd Britt, Ryan Sturm, Rick Ricardi, Virginia Labond Department of Emergency Medicine, Genesys Regional Medical Center, Grand Blanc, MI, USA Background: Thoracic trauma accounts for 10%–15% of all trauma admissions. Rib fractures are the most common injury following blunt thoracic trauma. Epidural analgesia improves patient outcomes but is not without problems. The use of continuous intercostal nerve blockade (CINB may offer superior pain control with fewer side effects. This study's objective was to compare the rate of pulmonary complications when traumatic rib fractures were treated with CINB vs epidurals. Methods: A hospital trauma registry provided retrospective data from 2008 to 2013 for patients with 2 or more traumatic rib fractures. All subjects were admitted and were treated with either an epidural or a subcutaneously placed catheter for continuous intercostal nerve blockade. Our primary outcome was a composite of either pneumonia or respiratory failure. Secondary outcomes included total hospital days, total ICU days, and days on the ventilator. Results: 12.5% (N=8 of the CINB group developed pneumonia or had respiratory failure compared to 16.3% (N=7 in the epidural group. No statistical difference (P=0.58 in the incidence of pneumonia or vent dependent respiratory failure was observed. There was a significant reduction (P=0.05 in hospital days from 9.72 (SD 9.98 in the epidural compared to 6.98 (SD 4.67 in the CINB group. The rest of our secondary outcomes showed no significant difference. Conclusion: This study did not show a difference in the rate of pneumonia or ventilator-dependent respiratory failure in the CINB vs epidural groups. It was not sufficiently powered. Our data supports a reduction in hospital days when CINB is used vs epidural. CINB may have advantages over epidurals such as fewer complications, fewer contraindications, and a shorter time to placement. Further studies are needed to confirm these statements

  18. 硬膜外分娩镇痛过程中不良反应观察及护理干预%Observation of adverse effects of epidural analgesia during childbirth and corresponding nursing interventions

    Institute of Scientific and Technical Information of China (English)

    韦冬英; 陈霞; 张海云

    2013-01-01

    Objective To discuss the adverse effects of epidural analgesia during childbirth and corresponding nursing interventions. Methods The study recorded the adverse effects of epidural analgesia on 49 parturients during childbirth, such as uterine inertia, supine hypotensive syndrome, fetal distress, urine retention and pain from perineal wound, and took corresponding nursing interventions. Results Satisfactory results were obtained after careful observation and prompt nursing interventions. Conclusion Careful observation, early discovery of adverse effects and prompt implementation of nursing interventions can improve the efficacy and safety of epidural analgesia during childbirth.%目的:探讨硬膜外分娩镇痛过程中不良反应及护理干预。方法记录49例孕妇进行硬膜外分娩镇痛过程中不良反应,如宫缩乏力、仰卧位低血压综合征、胎儿窘迫、尿潴留、会阴伤口疼痛等;针对不良反应进护理干预。结果通过仔细观察并及时护理干预,获得满意效果。结论仔细观察,及早发现不良反应,积极实施护理干预,可提高硬膜外分娩镇痛效果和安全。

  19. Effect of epidural labor analgesia on labor process and the outcome of delivery%硬膜外分娩镇痛对产程进展及分娩结局的影响

    Institute of Scientific and Technical Information of China (English)

    王俊; 胡娟; 柯文娟

    2016-01-01

    Objective:To investigate the effects of epidural labor analgesia on labor and delivery outcome.Methods:200 cases of pregnant women with epidural analgesia were selected.They were randomly divided into the study group and the control group with 100 cases in each group.The control group took vaginal birth childbirth.The analgesia group took epidural analgesia in post parturient.Results:The level of pain of the control group was significantly higher than that of the analgesia group(P<0.05).The first production process time and the second production process time of the analgesia group were shorter than those of the control group(P<0.05).The maternal mode of delivery of the two groups had statistically significant(P<0.05).Conclusion:Epidural analgesia can significantly reduce maternal pain,reduce the rate of cesarean section,promote birth.%目的:探讨硬膜外分娩镇痛对产程及分娩结局的影响。方法:收治硬膜外分娩镇痛产妇200例,随机分成镇痛组和对照组各100例,对照组采取经阴道顺产分娩,镇痛组在产妇临产后进行硬膜外分娩镇痛。结果:对照组疼痛级别明显高于镇痛组(P<0.05),镇痛组第一产程时间和第二产程时间明显短于对照组(P<0.05),两组产妇分娩方式比较,差异有统计学意义(P<0.05)。结论:硬膜外分娩镇痛可以明显降低产妇的痛感,减少剖宫产率,促进顺产。

  20. Avulsión del plexo braquial traumático no controlado con remifentalino: Papel de la analgesia epidural cervical Traumatic brachial plexus root avulsion unresponsive to remifentanyl role cervical epidural analgesia

    Directory of Open Access Journals (Sweden)

    M. Cortiñas

    2007-04-01

    Full Text Available Presentamos el caso de una paciente que sufrió accidente de tráfico con avulsión del plexo braquial izquierdo, y que presentaba dolor muy intenso (escala visual analógica 8 de características neuropáticas en la fase aguda postraumática. Dosis altas de remifentanilo fueron inefectivas para control del cuadro álgico, el cual se trato con éxito con una infusión de ropivacaína a través de catéter epidural cervical (C5-6. El dolor es controlado en fase crónica (escala visual analógica 2 con agentes específicos contra dolor neuropático (gabapentina, amitriptilina, clonacepam y tramadol.We presented you a patient who suffered a left brachial plexus avulsión with hard neuropatic pain in the posttraumatic acute phase (visual analogue scale 8. High-dose remifentanil infusión was uneffective in controlling pain, which was further ameliorated by ropivacaine infused through a cervical (C5-6 epidural catheter. At discharge pain remained controlled (visual analogue scale 2 with specific treatment against neuropathic pain (gabapentin, amytriptiline, clonacepam, and tramadol.

  1. 微信在术后使用PCEA患者中的应用%Application of Wechat in Patients Treated with Postoperative Epidural Controlled Analgesia (PCEA)

    Institute of Scientific and Technical Information of China (English)

    赖红燕; 沈洁; 邱小丹; 李军

    2016-01-01

    Objective To discuss the application effect of Wechat education in patient treated with postoperative epidural controlled analgesia (PCEA).Methods In total of 200 postoperative patients who need treated with PCEA were divided into two groups, control group and observation group. 100 patients in control group were educated routinely by nurses. 100 patients in observing group were educated by acute pain service group (APS) through Wechat. Routine education was adopted in control group and routine education combined with Wechat education during PCEA treatment until 24 hour after extubation was adopted in observation group.Results There was statistically significant difference in analgesic effect of the two groups (P0.05). According to the comparison of catheter care in the two groups, catheter extraction rate and pump loss rate in the two groups were similar, and there were no statistically significant differences (P>0.05). Catheter displacement rate in control group was 16%, and in observation group it was 14%. Catheter displacement rate in control group was higher, and the difference was statistically significant (P<0.01). According to the comparison of satisfaction degree, satisfaction rate in control group was 86% and in observation group was 100%. Satisfaction rate in observation group was higher and the difference was statistically significant (P<0.001).Conclusion Wechat education among postoperative patients treated with PCEA can improve the awareness of pain, self-management ability and nursing ability of patients, improve effect of analgesia, reduce the incidence rate of catheter displacement and increase satisfaction rate of patients.

  2. Patient-controlled epidural analgesia for labor pain in primipara%初产妇PCEA分娩镇痛的临床观察

    Institute of Scientific and Technical Information of China (English)

    郑丽娟; 刘晶; 胡祖荣; 黎昆伟; 黄希照

    2013-01-01

    Objective To explore the effects of patient-controlled epidural anesthesia (PCEA) on labor pain,birth process,and newborns.Methods 1200 puerperas were randomly divided into analgesia group and control group (n =600).The analgesia group received PC EA with sufentanil and ropivacaine; the control group re ceived conventional childbirth care.The degree of labor pain,duration of labor process,rate of oxytocin uses,postpartum hemorrhage volumn,rate of Cesarean section,and newborn states were noted.Results The degree of labor painin analgesiagroup(VAS scores were 43.1 ± 112,33.2± 13.7,13.6±6.7,and 10.3±4.1,respectively after analgesia.) was significantly lower than that in the control group (VAS scores were 82.9 ± 18.5,83.7 ± 18.1,and 80.3 ±17.3,respectively after analgesia) (P < 0.05).The active period of first stage of labor (157.7 ± 31.9)min in analgesia group was evidently shorter than that in the control group (P< 0.05).Rate of Cesarean section was significantly lower in analgesia group than in the control group(43% vs.53%,P < 0.05).Rate of oxytocin uses was obviously greater in analgesia group than in control group (61% vs.31%,P< 0.05).Postpartum hemorrhage volumn and Apgar score did not differ significantly between the two groups (P>0.05).Conclusions Patient-controlled epidural anesthesia is safe and effective in relieving labor pain.It can meet the needs for maternal analgesia and has no adverse effects on mothers and babies.%目的 探讨硬膜外自控镇痛(PCEA)分娩镇痛对产痛、产程和新生儿的影响.方法 将1200例产妇随机分为镇痛组和对照组,每组600例;镇痛组行舒芬太尼复合罗哌卡因连续硬膜外分娩镇痛,对照组常规分娩处理.观察记录两组产痛程度、产程时间、缩宫素使用率、产后出血量、剖宫产率以及新生儿情况.结果 镇痛组镇痛后10 min、30 min、60 min、宫口开全时产痛VAS评分分别为(43.1±11.2)、(33.2±13.7)、(13.6±6.7)、(10

  3. Comparison of influence of high thoracic epidural anesthesia and central analgesia on hemodynamic during on-bypass coronary artery bypass grafting

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    V. A. Sobokar

    2015-06-01

    Full Text Available Objective. Despite some advantages, the use of high thoracic epidural anesthesia (HTEA during cardiac operations may be discouraged by fear of adverse hemodynamic effects. Aim. To compare the hemodynamic effects of HTEA and central analgesia (CA during on-bypass CABG. Methods. 132 patients were assigned into two groups – study group (n = 85, where the surgery was carried out under HTEA and control group (n = 47 - where the surgery was carried out under CA. Data of the intraoperative monitoring and trans-oesophageal cardiac ultrasound - cardiac index (CI, stroke index (SI, ejection fraction (EF and index of systemic vascular resistance (ISVR were obtained. Results. After induction and sternotomy patients in the study group had higher EF - 57(53, 65% vs 54 ± 7% (p = 0,013 and 55 ± 8 vs 52 ± 9%, (p = 0,031. After sternotomy CI and SI in the study group were also higher, respectively 2,42 (2,0;3,1 vs 2,23±0,63 l · min-1 · m-2, (p = 0,041 and 43 (34;46 vs 37±10 ml · m-2 (p = 0.014. Conclusion. We concluded that HTEA has advantages over CA by its influence on hemodynamics.

  4. 可行走硬膜外阻滞分娩镇痛的临床研究%Clinical study on walking epidural labor analgesia

    Institute of Scientific and Technical Information of China (English)

    夏继林; 刘兴业; 高显舜; 周伟; 周耀朝; 杨萱

    2013-01-01

    Objective To observe the effect ropivacaine mesylate combined with sufentanil on walking epidural laboranalgesia.Methods 360 puerperae who accepted 0.12% ropivacaine mesylate combined with sufentanil (0.5 μg/ml) epidural analgesia were analgesic group;at the same time and under the similar conditions,the 356 cases of puerprtae unused analgesic were control group.With visual analogue scale(VAS) assessing the uterine contraction pain and improved Bromage scale assessing lower limb movement block,recording the analgesic effect,every labor time,delivery mode,and the condition of postpartum hemorrhage,fetal distress and neonatal Apgar score in every group.Results Labor pain of pain group significant relief,the active period shorten and the vaginal eutocia percentage were higher than those in the control group; Labor time of the secend and the third stage,vaginal birth rate and oxytocin utilization rate had no differences between the two groups.Conclusion The effect of epidural block labor analgesia on 0.12% ropivacaine mesylate combined with sufentanil is obvious and security.There is no motor nerve block and do not affect the stage of labor and neonatal.It still can reduce the rate of cesarean section and improve maternal satisfaction.%目的 观察甲磺酸罗哌卡因复合苏芬太尼用于硬膜外阻滞可行走分娩镇痛的效果.方法 选择接受0.12%甲磺酸罗哌卡因复合苏芬太尼(0.5μg/ml)硬膜外镇痛的360例产妇作为镇痛组,在同期条件相似未行镇痛的356例产妇为对照组.采用视觉模拟评分(VAS)评估宫缩时疼痛,改良Bromage评分评估下肢运动阻滞,记录镇痛效果、产程时间、分娩方式、产后出血、胎儿窘迫和新生儿Apgar评分情况.结果 镇痛组较对照组在镇痛后30 min、宫口开全、胎儿娩出时疼痛明显缓解,活跃期缩短,阴道顺产率高,剖宫产率低(t=31.989、39.586、35.893、-12.382,x2=34.685、36.854,均P<0.05);两组第二产程、第三产

  5. Side effects of subarachnoid and epidural sufentanil associated with a local anesthetic in patients undergoing labor analgesia

    OpenAIRE

    Salem, Isabel C.F. [UNESP; Fernanda B. Fukushima; Giane Nakamura; Fábio Ferrari; Navarro,Laís C.; Yara Marcondes Machado Castiglia; Eliana Marisa Ganem

    2007-01-01

    JUSTIFICATIVA E OBJETIVOS: A associação do opióide ao anestésico local melhora a qualidade da analgesia de parto e reduz o risco de toxicidade sistêmica pelo anestésico local. Os opióides, entretanto, podem determinar efeitos colaterais. O objetivo desta pesquisa foi comparar os efeitos adversos determinados pelo sufentanil, administrado por via subaracnóidea, associado à bupivacaína, com aquele determinado pelo sufentanil por via peridural, associado à ropivacaína, nas doses utilizadas no Se...

  6. 孕妇自控硬膜外镇痛分娩知识调查分析%Investigation and analysis about parturition related knowledge of patient-controlled epidural analgesia among pregnant women

    Institute of Scientific and Technical Information of China (English)

    王丽敏; 燕美琴; 胡燕利

    2015-01-01

    Objective To know the awareness level of patient-controlled epidual analgesia in labor related knowledge,and to provide evidence for health education,develop a comprehensive intervention program to reduce the rate of cesarean section.Methods Investigation on knowledge of patient controlled epidural analgesia during labor for a total of 400 pregnant women on Maternal and Child Health Hospital of Taiyuan City,MCH Hospital of Shanxi Province by questionnaire.Compared different characteristics of the pregnant women's scores about control epidural analgesia childbirth knowledge by nonparametric test,knowledge score of multi-factor analysis by multiple linear regression analysis.Results The maximum score of pregnant women-controlled epidural analgesia delivery knowledge was 13,the minimum score was 0,the median score was 4,range interquartile was 5.Different pregnant women with different age,education level,number of weeks of gestation,pregnancy,family income,and condition of parnatal care had different scores of knowledge of patient-controlled epidural analgesia,the difference was significant,P<0.05.Multiple linear regression analysis showed that:pregnant women's education,gestational age,the average monthly household income can be explained by maternal knowledge score of 61.4% of the variation.Conclusions The level of pregnant women-controlled epidural analgesia childbirth knowledge is low,we need to strengthen the natural childbirth education,and take a variety of modes of propaganda and increase their level of knowledge,enhance confidence of natural childbirth in pregnant women,so as to achieve the purpose of reducing cesarean section rate.%目的 了解孕妇自控硬膜外镇痛(patient-controlled epidural analgesia,PCEA)分娩相关知识的知晓水平,为更好地开展健康教育、制订降低剖宫产率的综合干预方案提供依据.方法 采用问卷调查法对山西省妇幼保健院、太原市妇幼保健院共410名孕妇进行PCEA分娩相

  7. Analgesia after cesarean section and epidural anaesthesia clinical study of the impact of maternal lactation%护理干预对剖宫产及硬膜外麻醉术后产妇泌乳的影响

    Institute of Scientific and Technical Information of China (English)

    温艳艳

    2014-01-01

    目的:观察剖宫产、硬膜外吗啡术后镇痛产妇的泌乳状况及血清泌乳素(PRL)变化。方法:足月产妇240例均分为四组:Ⅰ组术毕行硬膜外吗啡镇痛;Ⅱ组术毕行硬膜外吗啡镇痛,24h后追加一次;Ⅲ组未行术后镇痛;阴道自然分娩60例为Ⅳ组。240例产妇产前、产后均进行护理干预、科学宣传,实行母婴同室和纯母乳喂养。结果:产后5min、24h及48h内开始泌乳及72h泌乳分泌不足发生率与剖宫产组相比无差异。结论:由于护理干预,剖宫产及硬膜外吗啡术后镇痛不影响产妇母乳喂养的成功率。%objective:To observe the cesarean section, epidural morphine postoperative analgesia maternity lactation status and serum prolactin (PRL) change.Methods:The240 cases of maternal term are divided into four groups:Ⅰ group operation BiHang epidural morphine analgesia;Ⅱ group operation BiHang epidural morphine analgesia, 24 h after additional one time.Ⅲ group do not postoperative analgesia; Vaginal natural childbirth sixty cases ofⅣ group. 240 cases were performed antenatal, postpartum nursing intervention, scientific propaganda, the maternal and child inmates and pure breastfeeding.Results:Postpartum 5 min, 24 h and h and start within lactation and 72 h lactation hyposecretion incidence and cesarean section group compared with indifference.Conclusion:Due to the nursing intervention, and cesarean section and epidural morphine postoperative analgesia does not affect maternal breastfeeding success rate.

  8. 产妇自控硬膜外分娩镇痛的产科结局临床分析%Obstetric outcomes of patient-controlled epidural labor analgesia

    Institute of Scientific and Technical Information of China (English)

    倪倩; 陶敏芳; 周伟伟; 钱刚

    2012-01-01

    目的 探讨自控硬膜外分娩镇痛(patient-controlled epidural labor analgesia,PCEA)对产科结局的影响.方法 随机选取488例产妇,其中244例采用PCEA分娩镇痛,另外244例常规分娩为对照组,分别对两组在分娩疼痛程度、产程、产后出血、分娩过程中胎儿宫内窘迫发生、新生儿Apgar评分、剖宫产率等方面对照分析.结果 PCEA分娩镇痛组Mulleetr疼痛强度≤2有237例(97.13%),而对照组仅78例(31.97%),两组有显著差异.两组在产程、产后出血、分娩过程中胎儿宫内窘迫发生、新生儿Apgar评分、剖宫产率等方面比较无统计学差异.结论 PCEA分娩镇痛是一种对孕妇高效、安全、对胎儿无不良反应的分娩镇痛方法.PCEA分娩镇痛对产程的延长影响作用很小,并不增加剖宫产率及难产率.%Objective To evaluate the obstetric outcomes in lying-in women with patient-controlled epidural labor analgesia (PCEA). Methods Total 448 primiparae with a full term singleton fetus were randomly divided into patient-controlled epidural labor analgesia group ( PCEA group, n = 244) and normal labor without analgesia group (control group, n =244). The Mulleetr labor pain grade, stage of labor, flooding, fetal distress rate, newborn Apgar scores and rate of cesarean section were observed and compared in two groups. Results There were 237 parturients in PCEA group(97.13% ) and 78 in control group (31.97% ) having a Mulleetr labor pain grade ≤2 (p<0.0l). There were no statistically significant differences in rate of cesarean section, newborn Apgar scores, stage of labor and flooding between two groups. Conclusion Patient-controlled epidural labor analgesia is satisfactory and safe for parturients and infants.

  9. Perbandingan Analgesia Epidural Menggunakan Bupivakain 0,125% dengan Kombinasi Bupivakain 0,0625% dan Fentanil 2 μg/mL terhadap Nyeri dan Blok Motorik pada Persalinan Normal

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    Oktofina K. Mose

    2015-03-01

    Full Text Available Epidural analgesia became the gold standard to facilitate normal labor without pain. The purpose of this study was to compare bupivacaine 0.125% versus bupivacaine 0.0625% + fentanyl 2 μg/mL epidural analgesia in the reduction of pain during labor as measured by the numeric rating scale (NRS and motor block was assessed using the bromage score. A randomized double blind controlled clinical trial was conducted on 34 primigravida parturien with ASA physical status II planned for vaginal birth at delivery in delivery room Dr. Hasan Sadikin Hospital-Bandung within December 2011–June 2012. Subjects were randomly assigned into two groups. The research data were analyzed using of the chi-square and independent ttest with 95% confidence level and considered significant when p0.05. Bromage score B vs BF group significantly different with p value <0.05 at 90 minutes. This study concluded that the combination of 0.0625% bupivacaine + fentanyl 2 μg/mL produce analgesia similar to that provided by infusion of 0.125% bupivacaine and reduce the incidence of motor block during labor.

  10. Clinical analysis on application of continuous epidural analgesia in multiparous women%连续硬膜外阻滞分娩镇痛法应用于经产妇的临床分析

    Institute of Scientific and Technical Information of China (English)

    贾国占; 崔世红; 程国梅; 张婷; 刘萍萍; 蔡一鸣

    2011-01-01

    目的:探讨连续硬膜外阻滞分娩镇痛法的镇痛效果和对产程、母婴的影响以及经产妇有无必要采用镇痛分娩.方法:选择自愿要求分娩镇痛无禁忌证的足月经产妇80例作为观察组(A组),给予连续硬膜外分娩镇痛;同期要求分娩镇痛无禁忌证的足月初产妇80例作为对照1组(B组),同样给予连续硬膜外分娩镇痛;另设同期未行分娩镇痛的足月经产妇80例作为对照2组(C组),观察产妇生命体征、胎心,记录第一、二、三产程时间,疼痛的视觉模拟评分(VAS评分)、Bromage评分、分娩方式、缩宫素使用率、新生儿Apgar评分、产妇出血量等.结果:连续硬膜外阻滞分娩镇痛方法效果确切有效,A组与B组相比VAS评分差异无统计学意义,与C组相比差异有统计学意义,PA-C<0.01;A组产程快于C组,C组快于B组,经统计学分析,A组和C组第一产程活跃期和第二产程差异有统计学意义,PA-C<0.05,A、C两组与B组相比差异均有统计学意义,PA-B<0.05、PC-B<0.05;3组阴道手术产率和剖宫产率比较,差异无统计学意义;3组的Bromage评分比较,差异无统计学意义;A组和B组的缩宫素使用率高于C组,差异有统计学意义,PA-C<0.05、PB-c<0.05,A、B两组之间相比,B组较高,但差异无统计学意义;3组出血量差异无统计学意义;3组的新生儿Apgar评分相比,差异无统计学意义;结论:连续硬膜外阻滞分娩镇痛法安全有效,且运动阻滞轻,用药量少,适用于初产妇,同样也适用于经产妇,经产妇亦应根据情况和需要采用分娩镇痛.%Objective :To explore the analgesic effect of continuous epidural analgesia (CEA) and its effect on stages of labor, mothers and fetuses, and whether it is necessary for multiparous women to adopt continuous epidural analgesia for labor analgesia or not Methods:80 full term multiparous women adopting labor analgesia voluntarily and without contraindication of labor analgesia

  11. Clonidina e dexmedetomidina por via peridural para analgesia e sedação pós-operatória de colecistectomia Clonidina y dexmedetomidina por vía peridural para analgesia y sedación pós-operatoria de colecistectomía Epidural clonidine or dexmedetomidine for post-cholecystectomy analgesia and sedation

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    Antônio Mauro Vieira

    2004-08-01

    local anesthetic effects when epidurally administered. The goal of this study was to evaluate the analgesia and sedation promoted by clonidine or dexmedetomidine associated to epidural ropivacaine, in the postoperative period of subcostal cholecystectomy. METHODS: Forty patients of both gender participated in this randomized double-blind study , aged 18 to 50 years, weighing 50 to 100 kg, physical status ASA I or II, submitted to subcostal cholecystectomy. The subjects were distributed in two groups: Clonidine (CG, receiving clonidine (1 mL = 150 µg associated to 0.75% epidural ropivacaine (20 mL; Dexmedetomidine (DG, receiving dexmedetomidine (2 µg.kg-1 associated to 0.75% epidural ropivacaine (20 mL. Analgesia and sedation were evaluated 2, 6 and 24 hours anesthetic recovery. RESULTS: Both groups present some grade of sedation in the moments 2 and 6 hours , with statistically significant difference between the two moments for the dexmedetomidine group. There has been analgesia in both groups, especially at 2 and 6 hours. There have been statistically significant difference among periods of 2, 6 and 24 hours in the dexmedetomidine group; in the clonidine group, this statistically significant difference was observed between the periods of 2 and 6 hours and between 2 and 24 hours. CONCLUSIONS: Our results allowed to conclude that the association of clonidine or dexmedetomidine to 0.75% ropivacaine induces analgesia and sedation in 2 and 6 hours after anesthetic recovery in patients submitted to subcostal cholecystectomy and that clonidine promotes more prolonged analgesia.

  12. 连续硬膜外腔阻滞在分娩镇痛中应用%Application of Continuous Epidural Analgesia during Labor

    Institute of Scientific and Technical Information of China (English)

    鲍月茹; 华伟

    2001-01-01

    目的:通过30例产妇应用连续硬膜外腔注药行分娩镇痛,观察镇痛效果及对宫缩、产程、宫口开大、儿 头下降的影响,并行母血、脐血的血气分析。方法:在放置硬膜外腔管后产妇连续接受:(1)10ml0.125%布匹卡 因,(2)10ml 0.2%罗哌卡因,二者任选其一直至分娩。结果:注入初始量镇痛药后子宫收缩轻度抑制,持续10~15 分恢复。此后在连续输注及第二产程中无宫缩抑制现象。结论:低浓度硬膜外腔阻滞麻醉,可缩短产程、使儿头下 降及宫口扩张速率加快,降低产妇体力消耗,缓解胎儿循环系统,减少新生儿酸中毒发生率。%Objective: To observe the effects of continuous epidural analgesia during labor on uterine contraction,stages of labor,di- latation of cervix,descent of fetal head and blood gas analysis in mother and cord blood. Methods:After putting down an epi- dural catheter,each patient continuously received 10 ml of 0.125% bupivacaine or 10 ml of 0.2% lopicaine until the labor was over. Results:As the top-up dose was given,a mild depression of uterine activity lasting 10~15 minutes was noted. There was no depression of uterine activity during infusion period and second stage of labor. Conclusion: The continuons epi- dural analgesia during labor can shorten stages of labor,quicken rates of dilatation of cervix and descent of fetl head,reduce mother's physical consumption,relieve fetal blood circulation and decrease the incidence of neonatal acidosis.

  13. Clinical Observation of Epidural Analgesia for Labor Pain%硬膜外阻滞麻醉用于无痛分娩的临床观察

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    李仁兰; 周玮

    2012-01-01

      目的探讨分娩镇痛的效果及对产程、母婴的影响.方法采用PECA泵硬膜外腔给药用于分娩镇痛,观察产程时间、分娩方式、产后出血、胎儿宫内窘迫及新生儿窒息情况.结果观察组和对照组产程比较、两组分娩方式比较有显著性差异(P0.05).结论 PECA泵用于持续硬膜外腔给药镇痛,疼痛阻滞完善,加速了产程的进展,降低了剖宫产率阴道难产率,对母婴均无不良影响.%  Objective To study the pain relief effectiveness and its influence on the labor course, and both the mothers and the newborns. Methods The pump of PECA (patient controlled epidural analgesia) was used during labor in the study group. The labor course, the methods of delivery, the incidence of post partum hemorrhage, fetal distress and neonatal asphyxia were observed respectively in the groups. Results There were significant differences between both groups in the stage of labor and delivery modes. There were no significant differences in the incidences of post partum hemorrhage, fetal distress and neonatal asphyxia(P>0.05).Conclusion The pump of PECA during labor is safe and effective, which accelerates course of labor and reduce the rates of cesarean and dystocia.

  14. Effects of Combined Spinal-Epidural Analgesia during Labor on Postpartum Electrophysiological Function of Maternal Pelvic Floor Muscle: A Randomized Controlled Trial.

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    Ji-Juan Xing

    Full Text Available Combined spinal-epidural analgesia (CSEA is sometimes used for difficult births, but whether it contributes to postpartum pelvic muscle disorder is unclear. This randomized controlled trial examined whether CSEA given during labor affects the electrophysiological index of postpartum pelvic floor muscle function.A consecutive sample of primiparous women who delivered vaginally at term were randomly assigned to a CSEA group (n = 143 and control group (n = 142 between June 2013 and June 2014. All were assessed 6-8 weeks later for electrophysiological function of pelvic floor muscle.The two groups were similar in the degree of muscle strength, muscle fatigue, and pelvic dynamic pressure of pelvic floor muscle. The CSEA and control groups showed similar proportions of women with normal muscle strength (score ≥4 in type I pelvic fibers (23.1% vs. 14.1%, P = 0.051 and type II pelvic fibers (28.0% vs. 24.6%, P = 0.524. The groups also contained similar proportions of women who showed no fatigue in type I fibers (54.5% vs. 48.6%, P = 0.315 or type II fibers (88.8% vs. 87.3%, P = 0.699. Similarly low proportions of women in the CSEA group and control group showed normal pelvic dynamic pressure (11.2% vs. 7.7%, P = 0.321. However, women in the CSEA group spent significantly less time in labor than those in the control group (7.25 vs. 9.52 h, P <0.001.CSEA did not affect the risk of postpartum pelvic muscle disorder in this cohort of primiparous women who gave birth vaginally. A significant shorter duration of labour was observed in the CSEA-group.ClinicalTrials.gov NCT02334150.

  15. Analysis Effect of 120 Cases With Continuous Epidural Anesthesia for Labor Analgesia on Birth Process%持续硬膜外阻滞麻醉分娩镇痛对产程的影响120例分析

    Institute of Scientific and Technical Information of China (English)

    何红霞

    2015-01-01

    Objective To analysis the effect of continuous epidural anesthesia for labor analgesia on birth process.Methods Clinical data of 120 cases with continuous epidural anesthesia for labor analgesia and 120 cases without continuous epidural anesthesia for labor analgesia were respectively analyzed. birth process, pain, satisfaction, and adaptability of two groups were compared.ResultsPain, satisfaction, and adaptability scores of two groups,P<0.01, had difference statistically significance. In non pillow before entering the basin of maternal, the average time of miyaguchi 2 cm wide to full of labor analgesia group was longer than non-labor analgesia group,P<0.01, had difference statistically significance. In outlet diameter < BPD, the second stage of labor of labor analgesia group was longer than non-labor analgesia group,P<0.01, had difference statistically significance.Conclusion Continuous epidural anesthesia for labor analgesia can release maternal pain, and improve maternal degree of cooperation and satisfaction, and with less effect on birth process.%目的分析持续硬膜外阻滞麻醉分娩镇痛对产程的影响。方法回顾性分析采用持续硬膜外阻滞麻醉分娩产妇120例及选择分娩镇痛的产妇120例的临床资料。比较两组产妇产程、产程过程的疼痛程度、满意度、配合度情况。结果两组产程疼痛程度、分娩过程中配合度评分、产程过程的满意度评分比较,P<0.01,差异具有统计学意义。非枕前位入盆的产妇,镇痛组产妇平均宫口开大2 cm到开全时间长于未镇痛产妇,P<0.01,差异具有统计学意义。出口横径<双顶径的产妇,镇痛组第二产程时间长于未镇痛组的产妇,P<0.01,差异具有统计学意义。结论持续硬膜外阻滞麻醉分娩镇痛能够缓解产妇疼痛程度,提高产妇配合度及满意度,对产程的影响较小。

  16. Protocolo de analgesia epidural obstétrica en el contexto de la gestión innovadora de la asistencia y de los criterios de calidad y seguridad Guidelines for obstetric epidural analgesia within a framework of innovative managementand quallity and safety criteria

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    C. Campuzano

    2007-03-01

    Full Text Available La Analgesia Epidural Obstétrica en nuestro hospital, comienza en el año 2000 a los pocos meses de inaugurar el nuevo Hospital Comarcal de Antequera. Elaboración de un Protocolo y la presencia de un Coordinador entre los distintos colectivos fueron los primeros pasos hasta el año 2002. La Unidad de Gestión Clínica del Bloque Quirúrgico comienza a funcionar en el año 2002 e implica directamente otra dinámica de trabajo, a saber: participación en el Proceso Integrado Embarazo-Parto-Puerperio y su relación con Asistencia Primaria de Salud, Actividad Asistencial Obstétrica marcada por objetivos de productividad, Recursos Humanos y Carga de Trabajo implicada en la analgesia obstétrica, Medios Materiales necesarios, Gestión de los recursos económicos, Mapa de Competencias específicas para los profesionales implicados e Informatización de las técnicas analgésicas dirigida a la obtención de determinados indicadores de actividad con los datos estadísticos pertinentes. Criterios de Calidad y de Seguridad desarrollados en la Unidad de Gestión Clínica serán expuestos en este artículo: Audits Clínicos de cumplimentación del protocolo, eficacia analgésica, satisfacción del usuario, valoración de partos instrumentales, inicio de epidural ambulante, control de la morbilidad a través de otro protocolo de Complicaciones de Loco-Regional de la Unidad, detección de eventos adversos y valoración e investigación de los casos centinelas ocurridos. Indudablemente no basta con efectuar la técnica, la Unidad Clínica y sus Objetivos han creado mecanismos de información sobre lo que hacemos y sobre las rectificaciones y mejoras a implementar. Es el camino a seguir y incluye un periodo de adaptación de los profesionales donde las motivaciones tanto económicas como de satisfacción profesional van marcadas por objetivos. Saber negociar estos objetivos anuales entre los gestores y los profesionales es el reto del futuro

  17. Subcutaneously tunneled epidural catheters for postoperative analgesia in iabetes patients with tumor%经皮下放置硬膜外导管应用于糖尿病肿瘤患者的术后止痛

    Institute of Scientific and Technical Information of China (English)

    蒲斌

    2013-01-01

    Objective To investigate the effects of subcutaneously tunneled epidural catheters on epidural bacterial translocation in the management of postoperative analgesia for diabetes patients with tumor. Methods A total of 100 diabetes patients who were going to undergo Dixon operation were equally divided into two groups: tunneled epidural catheters group( group T )and control group( group C ). After the epidural puncture in an aseptic condition, the epidural catheters were placed between L1 and L2 spine clearance. Dilute local anesthetic and fentanyl infusions were used for postoperative analgesia. The epidural catheters were removed with aseptic technique and the tips( 2cm )were sent for microbiological culture after 3 days. Results In group C, bacteriological examination revealed the ratio of bacteria colonization was 26% ,mainly staphylococcus epidermidis( 61.5% ),followed by enterococcus( 15.4% ),gram-negative ba-cilli( 15.4% )and yeasts( 7. 7% ). In group T,the bacteria colonization only occurred in 8% of the patients, mainly staphylococcus epidermidis( 50% ),followed by enterococcus( 25% )and gram-negative ba-cilli( 25% ). Compare with the group C,the difference was significant(P <0. 01 ). Conclusion Subcutaneously tunneled epidural catheter can decrease the risk of bacteria colonization associated with postoperative epidural analgesia in diabetes patients with cancer.%目的 观察经皮下隧道头向放置硬膜外导管对伴有糖尿病的肿瘤患者行术后止痛时导管尖端细菌异生情况.方法 将100例伴有糖尿病拟行Dixon手术的直肠癌手术患者随机等分为经皮下隧道放置硬膜外导管组(T组)和对照组(C组),选取L1-2棘间隙在无菌条件下行硬膜外穿刺、置管,术后用0.75%布比卡因、恩丹西酮及芬太尼行硬膜外术后止痛,3d后在无菌条件下拔除硬膜外导管,剪取尖端2cm送细菌培养.结果 C组中硬膜外导管细菌异生发生率为26%,其中表皮葡萄球菌61.5%;肠球菌15

  18. Abscesso do músculo psoas em paciente submetida à analgesia por via peridural: relato de caso Absceso del músculo psoas en paciente sometida a analgesia por vía peridural: relato del caso Psoas muscle abscess after epidural analgesia: case report

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    Durval Campos Kraychete

    2007-04-01

    un catéter peridural se pone, y esa vigilancia debe mantenerse después de su retirada.BACKGROUND AND OBJECTIVES: Psoas muscle abscess is a rare complication of epidural analgesia. The adequate approach to this complication is fundamental for a good resolution. The objective of this report was to discuss the diagnosis and treatment of psoas muscle abscess. CASE REPORT: A female patient, 65 years old, with neuropathic pain in the lower limbs, difficult to control with systemic drugs. The patient was treated with epidural opioid and local anesthetic as an alternate treatment. Twenty days after the continuous epidural administration, the patient complained of lumbar pain, headache, and fever. A CT scan of the pelvis showed an abscess of the psoas muscle, thus, closed drainage and antibiotics were indicated. CONCLUSIONS: An adequate, continuous supervision of the patient is necessary when an epidural catheter is placed, and it should continue after its removal.

  19. Meningite após técnica combinada para analgesia de parto: relato de caso Meningitis después de técnica combinada para analgesia de parto: relato de caso Meningitis after combined spinal-epidural analgesia for labor: case report

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    Carlos Escobar Vásquez

    2002-06-01

    nuca. En el 13º día los síntomas pasaron a ser más intensos. Fue realizada punción lumbar. La historia clínica y el examen del líquor fueron compatibles con meningitis bacteriana. CONCLUSIONES: La técnica combinada (raqui-peridural para analgesia de parto está próxima de lo ideal. Cuidados con la técnica de anti-sepsia son necesarios para realización de bloqueos espinales. La complicación presentada ocurrió sin la aparente falla en la realización de la técnica, siendo una cuestión que es inherente al riesgo - beneficio que la técnica proporciona.BACKGRAUND AND OBJECTIVES: Meningitis is a serious complication, although rare in regional anesthesia. This report aimed at presenting a case which evolved to meningitis after combined labor spinal-epidural analgesia. CASE REPORT: Laboring patient, 25 years old, second gestation and previous c-section. Combined labor spinal-epidural analgesia was induced with double-puncture. Twenty-four hours later she presented with headache at rest, fever and mild chills, which regressed with symptomatic medication. Headache worsened in the 5th day. There were vomiting and neck pain in the 10th day. Symptoms became more severe in the 13th day. Lumbar puncture was performed. Clinical history and CSF analysis were compatible with bacterial meningitis. CONCLUSIONS: Combined labor spinal-epidural analgesia is very close to being the ideal technique. Care must be taken with the sterile technique to induce spinal blockade. The reported complication has occurred without an apparent technique failure and is inherent to technique’s risk-benefit ratio.

  20. COMPARISON BETWEEN FENTANYL 2 μG/mL VERSUS DEXMEDETOMIDINE 1.5 μG/mL AS ADJUVANTS WITH ISOBARIC BUPIVACAINE 0.0625% IN EPIDURAL LABOUR ANALGESIA

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    Karuna Harsoor

    2016-11-01

    Full Text Available BACKGROUND Low-dose bupivacaine with opioids like fentanyl have been used traditionally as an adjunct for epidural labour analgesia, but has side effects like pruritus, urinary retention, nausea, vomiting, etc. Dexmedetomidine, an α-2 adrenergic agonist with a high placental retention, decreased sympathetic outflow and norepinephrine release thereby causing sedation, anxiolysis, analgesia, sympatholysis and maternal haemodynamic stability. Hence, this study was carried out to compare dexmedetomidine and fentanyl as adjuvants in epidural labour analgesia. MATERIALS AND METHODS A prospective randomised, double-blind study was conducted in 60 term parturients in active labour of ASA I and II physical status. They were randomised into 2 groups with 30 parturients in each and received 15 mL of 0.0625% Inj. Bupivacaine plus either 1.5 μg/mL Inj. Dexmedetomidine (BD group or 2 μg/mL Inj. Fentanyl (BF group. VAS, sedation scores, modified four grade Bromage scale, haemodynamics, peripheral oxygen saturation were recorded at baseline and regular intervals. When VAS was ≥4, subsequent doses of 5 mL of the respective group drug was administered. Parturients were ambulated when Bromage scale was 0 with no postural hypotension. Duration of analgesia, labour outcome, neonatal Apgar scores and side effects were noted. RESULTS Demography and haemodynamic stability were similar and comparable. Duration of analgesia was significantly longer in BD group (131.83±45.760 than BF group (85.33±22.512 (p<0.0001. More no. of top-ups was needed in BF group (1.80±1.518 than BD group (0.17±0.461 (p<0.0001. Significantly reduced VAS scores was observed in BD group than BF group. Mean sedation scores (p<0.05 and maximum Bromage scores (p=0.004 were significantly higher in BD group than BF group. Ambulation was less in BD group (3 parturients than BF group (26 parturients. Side effects were significantly more in BF group than BD group (p=0.007. The labour outcomes

  1. 硬膜外镇痛联合导乐方式在初产妇分娩镇痛中的效果%Effects of epidural analgesia combined with Doula method (导乐) on labor analgesia in primiparous women

    Institute of Scientific and Technical Information of China (English)

    苏松德; 付丽华; 黄淑平; 倪洪湖; 曾晖; 黄小花

    2016-01-01

    目的 观察硬膜外镇痛联合导乐方式在初产妇分娩镇痛中的效果.方法 初产妇分娩600例,ASA Ⅰ级,随机分为3组:硬膜外镇痛组(A组)、导乐组(助产士指导,B组)、硬膜外镇痛联合导乐组(C组),各组分别完成产道分娩者168、166、170例.记录各组产妇的镇痛情况,采用视觉模拟评分法(VAS)评价其镇痛效果、采用改良Bromage评分评价其神经阻滞情况,记录各组产妇的产程、满意度、分娩方式、新生儿Apgar评分与不良反应.结果 A、C两组镇痛后15 min时VAS评分较镇痛前降低(P<0.05).B、C组第一、第二产程较A组短(P<0.05).C组产妇的满意度较A、B两组高(P<0.05).结论 硬膜外镇痛联合导乐方式应用于分娩镇痛效果好,对产妇及新生儿无影响,产程缩短.%Objective To observe the clinical effects of epidural analgesia combined with Doula method (导乐) on labor analgesia in primiparous women.Methods Six hundred ASA Ⅰ primiparas were randomly divided into three groups.Epidural analgesia was used in group A,Doula method (guiding by midwife) in group B,and epidural analgesia combined with Doula method was used in group C.168,166 and 170 cases finished the vaginal delivery in the three groups respectively.The visual analogue scale (VAS),modified Bromage score (MBS),duration of labor,maternal satisfaction,mode of deliveries and neonatal Apgar score were recorded.Results VAS was significantly lower than pre-analgesia at 15 min after analgesia in group A and C (P< 0.05).Duration of the first and second stages of parturition in group B and C was significantly shorter than that in group A(P< 0.05).The maternal satisfaction score was significantly higher in group C than that in group A and B (P< 0.05).Conclusion Epidural analgesia combined with Doula method for labor analgesia is effective,and can shorten the labor stage with little impact on the primiparas and the neonates.

  2. Bloqueio combinado para analgesia de parto: a adição de sufentanil ao anestésico local influencia o apgar dos recém-nascidos? Bloqueo combinado para analgesia de parto: ¿la adición de sufentanil al anestésico local influye en el apgar de los reciÿn nacidos? Combined spinal-epidural for labor analgesia: does the addition of sufentanil to the local anesthetic influence apgar scores of the newborns?

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    Domingos Dias Cicarelli

    2007-06-01

    Universidade de São Paulo (USP y evaluar si la utilización de sufentanil asociado al anestésico local en el BC altera el Apgar de los recién nacidos. MÉTODO: Se analizaron las fichas de anestesia en que se realizaron BC para la analgesia de parto durante 12 meses en el Hospital Universitario de la USP. Se registraron el uso y la dosis de sufentanil, la vía de parto utilizada y las puntuaciones de Apgar del 1°, 5° y 10° minutos de los recién nacidos. RESULTADOS: De los 635 BC evaluados, 307 utilizaron sufentanil y anestésico local (Grupo SUF y 328, solo anestésico local (Grupo AL. Ciento veinte y siete (20% fueron realizados a través de la técnica de aguja por dentro de aguja y los otros 508 (80% realizados por la técnica dos punciones. No se verificó diferencia entre el Apgar de los grupos estudiados en el 1°, 5° y 10° minutos. CONCLUSIONES: El sufentanil utilizado en el bloqueo combinado no alteró el Apgar de los recién nacidos.BACKGROUND AND OBJECTIVES: Combined spinal-epidural (CSE is a very common obstetric technique. However, the literature does not present a standardization regarding the technique, doses, and anesthetics used, besides there is also the controversy about the possibility that the addition of opioids to the local anesthetic causes fetal bradycardia and affects its vitality. The aim of this study was to identify the techniques and anesthetics used in the Anesthesiology Service of the Hospital Universitário of Universidade de São Paulo (USP and determine whether the use of sufentanil associated with the local anesthetic affects Apgar scores of newborns. METHODS: The anesthesiology charts of patients submitted to CSE for labor analgesia over a 12-month period at the Hospital Universitário of USP were analyzed. The use and dose of sufentanil, the type of delivery, and Apgar scores in the 1st, 5th, and 10th minutes were recorded. RESULTS: Of the 635 CSE analyzed, 307 used sufentanil and local anesthetic (SUF Group and 328 only local

  3. 硬膜外预置管用于经产妇分娩镇痛临床分析%Clinical analysis of epidural preset tube in multipara labor analgesia

    Institute of Scientific and Technical Information of China (English)

    赵燕峰; 李斌; 欧阳雨芳

    2015-01-01

    Objective To investigate the validity, timeliness and security of epidural preset tube to block multipara la-bor analgesia, and to improve maternal labor analgesia rates and quality. Methods A total of 270 cases of mature ma-ternal in our hospital from May 2013 to October 2014 were chosen for the study, according to the study requirements, and they were divided into three groups. The observation group(group A) received PCEA labor analgesia method, and the control group1 (group B) received continuous epidural labor analgesia method, and the control group 2 (group C) did not undergo analgesia. Maternal vital signs and fetal heart rate in the three groups were observed, and the first stage of labor, the second stage of labor and the third stage of labor, pain visual analog scale (VAS score), Bromage score, mode of delivery, oxytocin usage rate, newborn Apgar score, maternal hemorrhage amount and the incidence of perineal lac-eration were recorded. Results There were not statistically significant differences in comparing general information of the 3 groups such as age, height, weight, gestational age(P>0.05). The differences in stage of labor and the incidence of perineal laceration in the three groups were statistically significant (P0.05). The differences were statistically significant in com-paring oxytocin usage rate, cesarean section rate, neonatal asphyxia score and postpartum hemorrhage amount in the observation group and the control group 2 (P0.05);三组的产程、会阴裂伤发生率相比差异有统计学意义(P0.05);观察组与对照2组在缩宫素使用率、剖宫产率、新生儿窒息率评分、产后出血量比较有统计学意义(P<0.05). 结论 连续硬膜外预置管法阻滞用于经产妇分娩镇痛安全有效,可以提高对产科并发症的手术麻醉处理的及时性、有效性,减少会阴裂伤发生率,增加经产妇分娩的安全性 .

  4. 腰硬联合阻滞麻醉在分娩镇痛中的应用分析%Application of combined splnal - epidural analgesia for labor pain relief

    Institute of Scientific and Technical Information of China (English)

    王天文

    2011-01-01

    目的 观察120例腰硬联合阻滞麻醉在分娩镇痛中的临床效果.方法 以120例腰硬联合阻滞麻醉镇痛的分娩产妇为治疗组,观察其临床疗效,并与对照组120例未行任何麻醉的产妇相比较,观察其产程、产后情况及胎儿情况.结果 两组在产后出血、新生儿窒息、胎儿窘迫、窒息方面无显著差异(P>0.05),在分娩方式及产程方面差异显著,有统计学意义(P<0.05).结论 腰硬联合麻醉分娩镇痛的方法能够加速第二产程快速进展,降低了阴道难产率及剖宫产率,对胎儿情况及产妇产后情况无明显影响,是消除分娩疼痛的有效措施.%Objective To assess the Application of combined splnal - epidural analgesia for labor pain relief. Methods 120 cases of lumbar epidural anesthesia for the treatment of maternal labor analgesia group, clinical efficacy and 120 patients with the control group of mothers received no anesthesia, compared to observe the birth process, post - natal conditions and fetal conditions. Results Two groups of postpartum hemorrhage, neonatal asphyxia, fetal distress, asphyxia no significant difference( P > 0.05 ), in the mode of delivery and birth process or its significant difference was statistically significant( P < 0.05 ). Conclusion Analgesia lumbar epidural anesthesia method can accelerate the second stage of rapid progress in reducing the rate of vaginal childbirth and planing Palace yield of postpartum fetal conditions and no significant effect on the situation, is an effective measure to eliminate labor pain.

  5. Tolerabilidad y eficacia de la morfina versus hidromorfona en analgesia epidural posquirúrgica con bupivacaína en un hospital universitario: ensayo ciego, con asignación aleatoria

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    Wilson Lescano

    2008-11-01

    Full Text Available OBJETIVO: comparar la frecuencia de efectos adversos (prurito, retención urinaria, náuseas, vómito, sedación y la eficacia analgésica entre hidromorfona y morfina en la analgesia epidural posoperatoria. MÉTODOS: ensayo clínico prospectivo, aleatorizado, ciego, para comparar los efectos adversos frecuentes relacionados con la morfina y la hidromorfona en dosis equivalentes asociadas a bupivacaína por vía epidural, en pacientes programados para cirugía mayor. Cada paciente recibió una combinación de hidromorfona 10 g/mL más bupivacaína al 0,1% (Grupo 1, HB o morfina 30 g/mL más bupivacaína 0,1% (Grupo 2, MB.Los pacientes se evaluaron a las 24 horas posoperatorias y se registraron los efectos adversos. RESULTADOS: participaron 142 pacientes: 71 en el Grupo HB y 71 en el Grupo MB. Las frecuencias de efectos adversos fueron como sigue en los grupos HB y MB, respectivamente: náuseas 31% y 36,6% (p = 0,54; vómito 25,4% y 19,7% (p = 0,42; sedación 14,1% y 15,5% (p =0,81; retención urinaria 7% y 11,3% (p = 0,38; prurito 31% y 43,7% (p = 0,11. No hubo diferencias estadísticamente significativas entre los dos grupos. La media en la escala verbal numérica medida a las 24 horas para dolor dinámico fue de 2,82 (± 2,5 y de 3,42 (± 2,8 para los grupos HB y MB, respectivamente (p = 0,16. La media de dolor en reposo tampoco mostró diferencia significativa. CONCLUSIÓN: no hay diferencias en la tolerabilidad entre la morfina 30 g /mL y la hidromorfona 10 g/mL como parte de un esquema combinado con bupivacaína al 0,1% para analgesia epidural posoperatoria y ambos opiáceos proveen analgesia efectiva y comparable.

  6. 潜伏期硬膜外阻滞分娩镇痛临床分析%A clinical analysis of epidural anesthesia in latency of labor for labor analgesia

    Institute of Scientific and Technical Information of China (English)

    尹春艳; 毛邱娴; 郭云怀; 张玲

    2011-01-01

    Objective To explore clinical characteristics and feasibility of epidural anesthesia parturition analgesia in latency (labor analgesia in brief). Methods 272 term primiparae with cephalic presentation who tried to deliver vaginally were divided into 3 groups according to their willings: group A ( n = 92, who didn't receive any analgesia in delivery), group B ( n = 85, who received labor analgesia in active stage of labor when their external cervical orifice dilated to 3cm) and group C ( n = 95, who received labor analgesia in latency when the external cervical orifice opened to 1 ~2cm). The term primiparae in groups B and C received catheter setting in epidural space plus parturient controlled analgesia (CSE + PCA ) for labor analgesia. The labor duration, pattern of delivery, incidences of postpartum hemorrhage and neonatal asphyxia of primiparae were compared among the three groups. Results The duration of latency of primiparae in group C (345 + 58 min) was shorter than that in group A (386 + 98 min) and group B ( 388 + 79 min) ( F = 9.77, P =0. 001 ), and the duration of active stage of labor of primiparae in group A ( 219 + 69 min) was longer than that in group B ( 147 + 59 min)and group C ( 141 + 72 ) ( F = 37.99, P < 0. 001 ). The proportion of primiparae in group A who were given oxytocin in delivery( 19.6% )was less than that in group B ( 80.0% ) and group C ( 85.3% ), the differences were statistically significant (X2 = 28. 9544, P <0. 0001 ). Among the three groups, there were no significant differences in durations of the second and the third stages of labor, rates of cesarean section, forceps delivery and spontaneous delivery, incidence of neonatal asphyxia and amount of postpartum hemorrhage ( all P >0.05 ). Conclusion Labor analgesia starting from latency of labor can effectively shortens duration of labor pain. Increased use of oxytocineffectively shortens durations of latency and active stages of labor. It does not increase the

  7. Analgesia perioperatória com infusão peridural contínua da combinação de morfina e clonidina em crianças submetidas a procedimentos cirúrgicos abdominais Analgesia perioperatoria con infusión peridural continua de la combinación de morfina y clonidina en niños sometidos a procedimientos quirúrgicos abdominales Perioperative analgesia with continuous epidural infusion of morphine combined with clonidine in children undergoing abdominal surgeries

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    Jyrson Guilherme Klamt

    2007-12-01

    y seis niños destinados a operaciones intra-abdominales fueron ubicados aleatoriamente en de los grupos. Los de los grupos recibieron, por vía peridural, bolus de morfina (8 µg.kg-1 y de clonidina (0,8 µg.kg-1 antes del inicio de la intervención quirúrgica, seguidos de infusión continua de clonidina (0,12 µg.kg-1.h-1 más morfina (1,2 µg.kg-1.h-1 en el Grupo I y el doble de esa dosis en el Grupo II, durante 24 horas. Fueron medidas las concentraciones inspiratorias de isoflurano durante la operación y el número de dosis (1 mg.kg-1 de tramadol durante 24 horas en el postoperatorio. RESULTADOS: Las concentraciones de isoflurano fueron significativamente menores con relación a los valores observados antes de la incisión quirúrgica después 60 y 90 minutos en los grupos II y I, respectivamente, sin embargo no hubo diferencia entre los de los grupos. El consumo de tramadol fue significativamente menor en el grupo 2, siendo que 7 (53,8% no necesitaron analgesia de rescate, sin embargo fueron observadas mayor sedación e hipotensión arterial. No fue observada depresión respiratoria en los de los grupos. CONCLUSIÓN: La infusión peridural de la combinación de bajas dosis de clonidina y morfina promovieron reducción de la necesidad de isoflurano en el período intraoperatorio y analgesia postoperatoria de buena calidad.BACKGROUND AND OBJECTIVES: The present study was developed to evaluate the analgesic effects of the epidural administration of a combination of morphine and clonidine, whose efficacy has been demonstrated in adults, on the consumption of isoflurane and postoperative consumption of analgesics in children. METHODS: Twenty-six children scheduled for intra-abdominal surgeries were randomly divided in two groups. Both groups received an epidural bolus of morphine (8 µg.kg-1 and clonidine (0.8 µg.kg-1 before the surgery, followed by the continuous infusion of clonidine (0.12 µg.kg-1.h-1 plus morphine (1.2 µg.kg-1.h-1 in Group I, and twice

  8. Estudo comparativo entre bupivacaína (S75-R25 e ropivacaína em bloqueio peridural para analgesia de parto Estudio comparativo entre la bupivacaína (S75-R25 y la ropivacaína en bloqueo epidural para analgesia de parto A comparative study between bupivacaine (S75-R25 and ropivacaine in spinal anesthesia for labor analgesia

    Directory of Open Access Journals (Sweden)

    Celso Schmalfuss Nogueira

    2010-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A anestesia peridural é utilizada para alívio da dor no trabalho de parto e está associada a baixos índices de complicações. Estudos com enantiômeros levógiros dos anestésicos locais demonstraram maior segurança em função da menor cardiotoxicidade. Este estudo teve o objetivo de avaliar a latência e a duração da analgesia e as repercussões maternas e fetais com o emprego da bupivacaína (S75-R25 e da ropivacaína quando utilizadas para analgesia de parto por bloqueio peridural. MÉTODOS: Realizou-se um ensaio clínico prospectivo, duplamente encoberto e aleatório, de 49 pacientes gestantes de termo, apresentando baixo risco, com indicação de parto vaginal, idade entre 15 e 35 anos, ASA I ou II distribuídas em dois grupos: GI - bupivacaína (S75-R25 0,25%; GII - ropivacaína a 0,20%. RESULTADOS: Evidenciou-se diferença estatisticamente significante entre os dois grupos 30 minutos após a instalação da peridural, sendo os escores de dor maiores no grupo que utilizou a ropivacaína. Não foram encontradas diferenças estatísticas significativas quanto a latência de analgesia, nível sensorial do bloqueio, volume de anestésico local, dose de resgate, duração do trabalho de parto e da analgesia, frequência de parto instrumental, alterações hemodinâmicas, escores de Apgar ou pH do cordão umbilical e incidência de eventos adversos. CONCLUSÕES: O uso de bupivacaína (S75-R25 e ropivacaína para a analgesia de parto proporcionou boas condições para a realização da anestesia peridural com pequenas ocorrências de eventos adversosJUSTIFICATIVA Y OBJETIVOS: La anestesia epidural se usa para el alivio del dolor en el parto y está asociada a bajos índices de complicaciones. Estudios con enantiómeros levógiros de los anestésicos locales, han demostrado una seguridad más elevada en función de una menor cardiotoxicidad. Este estudio quiso evaluar la latencia y la duración de la analgesia y

  9. Analgesia preemptiva com S(+cetamina e bupivacaína peridural em histerectomia abdominal Analgesia preemptiva con S(+cetamina y bupivacaína peridural en histerectomía abdominal Preemptive analgesia with epidural bupivacaine and S(+ketamine in abdominal hysterectomy

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    Ferdinand Edson de Castro

    2005-02-01

    fue posible demostrar efecto preemptivo con la utilización peridural de S(+cetamina y bupivacaína en las dosis utilizadas en histerectomía abdominal.BACKGROUND AND OBJECTIVES: This study investigates the ability of epidural S(+ketamine, NMDA receptor antagonist, plus local anesthetic (bupivacaine injection to promote preemptive analgesia in patients undergoing total abdominal hysterectomy, when this solution is administered before surgical incision. METHODS: Participated in this prospective double-blind study 30 patients were randomly assigned in two equal groups. Epidural injection and catheter insertion were performed at L1-L2 interspace. Group 1 (G1 patients received 17 mL bupivacaine 0.25% plus 3 mL S(+ketamine (30 mg, 30 min before surgical incision, followed by 20 mL saline 30 min after incision. Group 2 (G2 patients received 20 mL saline 30 min before surgical incision, followed by 17 mL bupivacaine 0.25% plus 3 mL S(+ketamine (30 mg 30 min after incision. General anesthesia was induced with propofol, pancuronium, O2 and isoflurane. Postoperative analgesia consisted of epidural fentanyl plus bupivacaine bolus with 4h minimal interval. If necessary, IV dipyrone supplementation was administered. Patients were evaluated for analgesia by a verbal and numeric scale (at recovery and every six hours until 24 postoperative hours. Time to first analgesic request and total analgesic requirements were recorded. RESULTS: There were no significant differences between groups in time to first analgesic request, total analgesic consumption and numeric or verbal scale pain scores. CONCLUSIONS: This study failed to demonstrate a preemptive effect of epidural administration of bupivacaine and S(+ketamine in the doses tested for abdominal hysterectomy.

  10. Epidural Naloxone to Prevent Buprenorphine Induced PONV

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    Ashok Jadon

    2008-01-01

    Full Text Available Epidural infusion of local analgesic and opioid are commonly used for postoperative pain relief. This combina-tion gives excellent anlgesia but nausea and vomiting remains a major concern. Low dose epidural naloxone prevents PONV induced by spinal opioids like morphine, fentanyl and sufentanil. However, it is not known that epidural naloxone administration prevents PONV induced by epidural buprenorphine. We have reported three cases of major abdominal operation in which lowdose epidural infusion of naloxone releived the symptom of buprenorphine induced severe PONV and improved the quality of analgesia.

  11. Study on clinical application of Lamaza delivery method combined with spinal-epidural anesthesia analgesia for labor analgesia%拉玛泽分娩法联合腰硬联合阻滞分娩镇痛的临床应用研究

    Institute of Scientific and Technical Information of China (English)

    宁丰; 韦凤莲; 周霓

    2012-01-01

    Objective: To explore the clinical effect of Lamaza delivery method combined with spinal - epidural anesthesia analgesia for labor analgesia. Methods: A total of 400 primiparous women were selected and divided into group A ( Lamaza delivery method combined with spinal - epidural anesthesia analgesia) , group B ( Lamaza delivery method) , group C ( spinal - epidural anesthesia analgesia) , and group D ( Doula labor, control group) , 100 primiparous women in each group; the degrees of pain during delivery, stages of labor, delivery modes, indications of cesarean section, doses of oxytocin, amount of postpartum hemorrhage, neonatal Apgar scores in the four groups were observed. Results; Compared with the other three groups, the degree of pain during delivery in group A relieved significantly, the stages of labor shortened, the rate of spontaneous delivery increased, the rate of cesarean section decreased, the dose of oxytocin increased, there were statistically significant difference in the above - mentioned indexes (P 0. 05 ) . Conclusion: Lamaza delivery method combined with spinal -epidural anesthesia analgesia used for labor analgesia can effectively relieve labor pain, shorten stages of labor, increase the rate of spontaneous delivery, and reduce the rate of cesarean section, which doesnt affect the amount of postpartum hemorrhage and neonatal Apgar score, but it can increase the dose of oxytocin.%目的:探讨拉玛泽分娩法联合腰硬联合阻滞分娩镇痛在分娩中应用的临床效果.方法:选择400例初产妇,分为拉玛泽联合腰硬联合阻滞分娩镇痛组(A组)、拉玛泽组(B组)、腰硬联合阻滞分娩镇痛组(C组)和导乐陪伴组(对照组D组),每组100人,观察产妇产时疼痛程度、产程时间、分娩方式、剖宫产指征、缩宫素使用、产后出血、新生儿Apgar评分等.结果:A组产妇与其他3组比较,产时疼痛程度明显减轻,产程时间缩短,自然分娩率上升,剖宫产率下降,缩宫素

  12. Clinical Effects of Patient-controlled Epidural Analgesia in Children%小儿术后硬膜外自控镇痛的临床效果

    Institute of Scientific and Technical Information of China (English)

    刘继云; 佘守章; 谢晓青

    2000-01-01

    Objective: To evaluate the feasibility and safety of postoperative patient-controlled epidural analgesia (PCEA)in children. Methods: Forty postoperative pediatric patients(5-11 years old)were divided into two groups. A and B. Both wereinstituted with postoperative PCEA with LCP model (loading dose 2.05 + 0.13ml), continuos infusion rate 0.82 + 0.15mi/h, PCA dose 0.81 + 0.16ml)by Graseby-9300 PCA pump. The PCEA solution of group A was 0.075% bupivacaine plus0.0012 % buprenorphine, that of group B was same while 0. 005% droperidol was added as an adjuvant. Results:The volumeof PCEA sdution consumption in group B was significantly less than that in group A on the first and second postoperative day (P< 0.01-0.05). Good analgesic efficiency with little side effects was obtained, as evaluated by the VASF emasay or D/D score and complications in two groups, but the analgesic effect of group B was better than that of group A. Conclusion: Thepediatric PCEA with low concentration of bupivaeaine plus buprenorphine is feasible and safe. Droperidol may enhance theanalgesic effects of PCEA.%目的:探讨小儿术后硬膜外自控镇痛(PCEA)的可行性和安全性。方法:术后5~11岁的小儿40例,分成A、B两组。A组镇痛液配方为0.075%布比卡因+0.0012%丁丙诺啡(12μg/ml),B组配方与A组相同并加入小剂量氟哌啶(50μg/ml)。以LCP模式(负荷量2.05±0.13ml,持续量0.82±0.15ml,PCA量0.81±0.16m1)实施PCEA。结果:B组2天用量均少于A组(P<0.01~0.05)。从三种评分指标(VASF、ramsay、D/D)和并发症综合比较分析,提示两组均能达到满意的镇痛效果,但B组优于A组。结论:小儿术后用0.075%布比卡因+丁丙诺啡行PCEA是安全有效的,辅助少量氟哌啶可进一步增强PCA效果。

  13. Effect of labor analgesia on labor outcome.

    Science.gov (United States)

    Halpern, Stephen H; Abdallah, Faraj W

    2010-06-01

    Labor is among the most painful experiences that humans encounter. Neuraxial analgesia is the most effective means of treating this pain. In this review, we discussed the effect of neuraxial analgesia on the progress of labor when compared with parenteral opioids. We then compared initiation of analgesia with a combined spinal-epidural technique (CSE) to conventional epidural analgesia. Finally we discussed the impact of neuraxial analgesia, given early in labor, compared with later administration. Compared with parenteral opioids, neuraxial analgesia does not increase the incidence of cesarean section, although it is associated with a longer (approximately 16 min) second stage of labor. The incidence of operative vaginal delivery is higher in the epidural group but this may be due to indirect reasons such as changes in physician behavior. There was no difference in labor outcome when CSE was compared with low-concentration epidural analgesia, but higher concentrations may prolong labor. Early administration of neuraxial analgesia does not increase the incidence of operative delivery or prolong labor. Neuraxial analgesia does not interfere with the progress or outcome of labor. There is no need to withhold neuraxial analgesia until the active stage of labor.

  14. Clinical analysis of effect of combined spinal - epidural anesthesia in labor analgesia%腰硬联合麻醉分娩镇痛临床效果分析

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    李如霞; 柯善高; 徐晓俊; 朱桃花

    2011-01-01

    目的 分析腰硬联合麻醉分娩镇痛对母儿的影响,并比较芬太尼和舒芬太尼的效果.方法 选择2010年3~9月行分娩镇痛的192例初产妇,与同期未行镇痛的98例(对照1组)和开展分娩镇痛前107例(对照2组)初产妇比较.结果 与对照1、2组比,镇痛组第二产程和活跃期时间延长,缩宫素使用率高,产钳助产率高,新生儿1 min Apgar评分轻度窒息率升高,差异有统计学意义(P<0.05);因胎儿窘迫剖宫产率、第三产程时间组间比较差异无统计学意义(P>0.05).镇痛组较对照1组,第一产程时间、因头盆不称剖宫产率、产后出血量差异明显(P<0.05).使用芬太尼及舒芬太尼镇痛产妇,副作用主要是皮肤瘙痒,前者虽高于后者,但无统计学意义(P>0.05).结论 腰硬联合麻醉分娩镇痛效果确切,镇痛药对新生儿评分稍有影响,但预后良好.%Objective To analyze the effect of combined spinal - epidural anesthesia (CSEA) for labor analgesia and the impact on mothers and children and to compare the effects of fentanyl and sufentainl. Methods From march 2010 to september 2010 192 primiparity with labor analgesia were choosed, and 98 cases without analgesia in the same period ( control 1 group) , and 107 cases before labor analgesia (control 2 group) for comparison. Results Compared with the 1 and 2 groups, the duration of the second stage of labor and active phase in the analgesia group were longer, the rates of oxytocin use and forceps delivery were higher, and one minute Apgar score newborn asphyxia increased slightly, and there were significant differences (P < 0. 05 ); cesarean section rate of fetal distress, the labor time of the third stage had no significant differences ( P > 0.05 ) in groups. Compared with the 1 group, the labor time of the first stage, the rate of cephalopelvic disproportion cesarean section, the volume of postpartum hemorrhage had significant differences (P <0.05 ). Side effect is

  15. Clinical Observation of the Effect of Epidural Analgesia duringSpontaneous elivery%硬膜外镇痛应用于自然分娩的临床观察

    Institute of Scientific and Technical Information of China (English)

    何天琼; 方光萍; 邓忠琼; 龙莉; 陈丽

    2012-01-01

    Objective To observe the effect of epidural analgesia on puerpera and newborn during spontaneous delivery. Method 118 puerpera through spontaneous delivery in our hospital were divided into two groups (according to their own choice), the observation group (54 puerpera which voluntary spontaneous delivery) and the control group (64 puerpera without spontaneous delivery). Then the pain degree of puerpera, total stage of labor, postpartum hemorrhage volume, Apgar score of the newborn were compared in the two groups. ResultsThe total stage of labor and the pain degree of puerpera were significantly decreased in the observation group (P0.05). Conclusions Epidural analgesia can shorten the total stage of labor, ease the pain of puerpera and it dosen’t have negative effect on the postpartum hemorrhage volume and Apgar score of the newborn.%目的观察硬膜外镇痛应用于分娩镇痛对产妇和新生儿的影响.方法选择同期自然分娩产妇118例,按产妇自愿选择的原则,分为观察组:要求实施分娩镇痛54例,对照组:选择自然分娩64例.观察项目:产妇疼痛程度,总产程时间,产后出血量,新生儿Apgar评分.结果两组比较产妇总产程时间观察组短于对照组(p0.05).结论分娩镇痛能缩短总产程、基本消除产痛,对产力、产后出血量及新生儿Apgar评分不产生负面影响.

  16. 365例硬膜外阻滞分娩镇痛母婴安全性临床研究%Clinical safety study of mothers and infants with epidural analgesia in labor

    Institute of Scientific and Technical Information of China (English)

    刘兴业; 夏继林; 杨煊; 潘海娟

    2013-01-01

    目的 研究小剂量低浓度的甲磺酸罗哌卡因注射液复合小剂量的舒芬太尼注射液实施硬膜外阻滞分娩镇痛的镇痛效果以及对产程、分娩方式、母儿的影响.方法 选择2011年6月至2012年5月之间在安康市妇幼保健院分娩,经自愿要求签署硬膜外阻滞分娩镇痛知情同意书者共365例作为研究对象(镇痛组);随机抽取同时期住院条件相似不愿采用硬膜外阻滞分娩镇痛的产妇365例为对照组,分别观察两组的镇痛效果、产程、分娩方式、剖宫产率、缩宫素应用、新生儿窒息及软产道损伤等母儿并发症.结果 镇痛组镇痛后疼痛程度明显减低(t=163.130,P<0.01),且活动不受限,活跃期比对照组明显缩短(t=-12.878,P<0.01),第二产程两组无差异.镇痛组改剖宫产率明显低于对照组(χ2=38.814,P<0.01).两组缩宫素应用、新生儿窒息、软产道损伤、产后出血及尿潴留差异均无统计学意义.结论 小剂量低浓度的甲磺酸罗哌卡因注射液复合小剂量的舒芬太尼注射液用于硬膜外阻滞分娩镇痛效果好,可缩短产程,无母儿并发症,能促进自然分娩,降低剖宫产率.%Objective To study the effect of small dose low-concentration of ropivicaine mesylate injection and sufentanil injection used in epidural analgesia in labor and their influence on labor, delivery mode and maternal and infant outcomes. Methods From June 2011 to May 2012 365 cases, willing to sign informed consent for epidural analgesia in labor and giving birth in Maternal and Child Health Hospital of Ankang, were selected as study subjects ( analgesia group ). Over the same period another 365 cases with similar conditions but not willing to accept epidural analgesia in labor were randomly selected as control group. The analgesia effect, labor process, delivery mode, rate of cesarean section, use of oxytocin and the complications of mothers and infants such as neonatal asphyxia and birth canal

  17. TRAMADOL VIA EPIDURAL EM CÃES SUBMETIDOS À SUBSTITUIÇÃO DO LIGAMENTO CRUZADO CRANIAL

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    Guedes Alonso Gabriel Pereira

    2002-01-01

    Full Text Available Dez cães foram submetidos à substituição experimental do ligamento cruzado cranial e receberam tramadol (1mg/kg pela via epidural lombo-sacra como técnica analgésica trans e pós-operatória. Avaliaram-se as funções cardiovascular e respiratória, o consumo de halotano e a analgesia pós-operatória. Observou-se estabilidade hemodinâmica e respiratória, analgesia adequada durante e após a cirurgia, bem como a possibilidade de redução no consumo de anestésico inalatório. Conclui-se que o tramadol epidural é efetivo como adjuvante anestésico em cães submetidos à substituição do ligamento cruzado cranial.

  18. Analysis of 80 cases of Doula combined with Epidural anesthesia in labor analgesia%导乐陪伴联合硬膜外麻醉镇痛分娩80例分析

    Institute of Scientific and Technical Information of China (English)

    张锦华

    2014-01-01

    Objective:To discuss the effectiveness of Doula combined with epidural anesthesia in labor analgesia. Methods: 80 cases of primipara without obvious cephalopelvic disproportion , pregnancy complications or pregnancy complications were selected,they were performed Doula and epidural anesthesia when their cervix open 2-3cm,anal-gesic effect,labor,mode of delivery ,blood losing after delivery,and Apgar's score were recorded.Results: All the cases have good effect of analgesics, high rate of natural delivery , shorter labor,low rate of neonatal asphyxia,and no adverse reaction .Conclusion: Doula combined with epidural anesthesia in labor analgesia can significantly reduce the labor pain, the cesarean section rate ,shorten the labor and reduce bleeding, but does not increase the rate of neonatal as-phyxia, or has side effects on mother and child,so it is worth widely applied .%目的:探讨导乐陪伴联合硬膜外麻醉用于分娩镇痛的效果。方法:选择80例无明显头盆不称,无妊娠并发症和妊娠合并症的初产妇,宫口开大2~3cm时施行导乐陪伴及硬膜外麻醉镇痛,记录镇痛效果、产程、分娩方式、产后出血及新生儿Apgar评分等。结果:所有产妇镇痛效果良好,阴道自然分娩率高,总产程缩短,新生儿窒息率低,无不良反应。结论:导乐陪伴联合硬膜外阻滞镇痛分娩,可显著减轻产时疼痛,降低剖宫产率,缩短产程,减少出血量,但不增加新生儿窒息率,对母婴无副作用,值得推广应用。

  19. 潜伏期硬膜外分娩镇痛对产程和分娩方式的影响%Epidural analgesia in latent phase of labor: effects on length of labor and mode of delivery

    Institute of Scientific and Technical Information of China (English)

    耿志宇; 吴新民; 李萍; 符莹莹

    2009-01-01

    Objective To compare the outcome of ropivaeaine plus sufentanil for patient-controlled epidural analgesia between nulliparous women presenting in latent and active labor. Methods 360 nulliparous parturients were randomized according to cervix dilation. Latent group (cervix dilation < 3 cm) received 0.1% ropivacaine with 0.5 μg/ml sufentanil and active proup (cervix dilation≥3 cm) receive0.15% ropivaeaine with 0. 5 μg/ml sufcntanil, both followed by an infusion of 0.1% ropivaeaine with 0.5 μg/ml sufentanil through PCEA. The PCEA pump was programmed to infuse a 6 ml bolus with a lockout interval of 15-20 min. The following were recorded: (1) pain intensity evaluated using VAS (0-10), (2) motor block assessed using modified Bromage scale, (3) onset of analgesia after epidural injection, (4) fetal heart rate, (5) maternal vital signs, (6) apgar score, (7) labor process, (8) mode of delivery and (9) the total amount of analgesic consumed. Results Both groups provided good analgesia. Early administration of epidural analgesia did not prolong the duration of first and second stage of labor. However, group L had a significant higher caesarean section rate and a significant lower instrumental delivery rate than group A. The reasons of cesarean section in both groups were arrested active phase and fetal distress. The reasons of instrumental delivery in both groups were fetal distress. The neonates had good outcome in both groups. Conclusions Compared with epidural analgesia in active phase of labor, early administration of epidural analgesia in latent phase did not prolong labor, however, the caesarean section rate was increased and instrumental delivery rate was decreased.%目的 比较初产妇潜伏期和活跃期分娩镇痛的产程和分娩方式.方法 自愿接受分娩镇痛无产科及硬膜外阻滞禁忌证的单胎孕初产妇360例,按宫口扩张度分为两组.潜伏期组(L组):当宫口<3 cm时进行硬膜外穿刺,注入0.1%罗哌卡因和0.5

  20. Transplacental transfer and neonatal influences of sonophoretically administered sufentanil versus epidural sufentanil in labor peridural analgesia: A randomized prospective double-blind contemplate

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    Riham Hussein Saleh

    2014-10-01

    Conclusion: Sufentanil transplacental transport and fetal exposure appeared greater in epidural than in sonophoretic sufentanil. The former group women were facing more difficulty at starting breast-feeding on postpartum day 1 and were more apt to have stopped breast-feeding 6 weeks postpartum than the latter group women.

  1. Estudo comparativo entre fentanil por vias peridural e venosa para analgesia de operações ortopédicas Estudio comparativo entre fentanil por vías peridural y venosa para analgesia de operaciones ortopédicas Comparative study of epidural and intravenous fentanyl for postoperative analgesia of orthopedic surgeries

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    Marcelo Soares Privado

    2004-10-01

    miembro inferior. MÉTODO: El estudio fue aleatorio y duplamente encubierto. Cuando presentaban dolor pos-operatorio, los pacientes del G1 (n = 14 recibieron 5 ml de solución (100 µg de fentanil en solución fisiológica a 0,9% por vía peridural y 2 ml de solución fisiológica a 0,9% por vía venosa, los del G2 (n = 15 recibieron 5 ml de solución fisiológica a 0,9%, por vía peridural y 2 ml de fentanil (100 µg por vía venosa. Fue evaluada la necesidad de complementación analgésica con tenoxicam (40 mg por vía venosa y con bupivacaína a 0,25% (5 ml por vía peridural (cuando no había alivio con tenoxicam. La intensidad del dolor fue evaluada por las escalas numérica y verbal en los momentos M30, M120 y M240 minutos. RESULTADOS: El número de pacientes que necesitaron de complementación analgésica, tanto con el tenoxicam (G1 = 10 y G2 = 15 pacientes cuanto con la bupivacaína (G1 = 2 y G2 = 8 pacientes fue mayor en el G2. No hubo diferencia estadística en la intensidad del dolor entre los grupos en los tiempos evaluados. CONCLUSIONES: En las condiciones de este estudio el efecto analgésico del fentanil peridural es mejor que por vía venosa.BACKGROUND AND OBJECTIVES: There are controversies about the action site of lipophylic opioids after epidural injection. Some authors believe that these drugs act at supraspinal level, while others propose a spinal action. This comparative study aimed at answering this question by comparing epidural and intravenous fentanyl for postoperative analgesia of lower limb orthopedic procedures. METHODS: This was a randomized double-blind study. At postoperative pain complaint, G1 patients (n = 14 received 5 mL epidural solution (100 µg fentanyl in 0.9% saline and 2 mL of intravenous 0.9% saline; G2 patients (n = 15 received 5 mL epidural 0.9% saline and 2 mL intravenous fentanyl (100 µg. Analgesic complementation with intravenous tenoxicam (40 mg and epidural 0.25% bupivacaine (5 mL (when there was no relief with tenoxicam

  2. Clinical research on different concentrations of ropivacaine in walking epidural labor analgesia%不同浓度罗哌卡因用于可行走性硬膜外分娩镇痛的临床研究

    Institute of Scientific and Technical Information of China (English)

    袁庆明; 周传华; 莫洁平; 梁鉴华; 曾馨文

    2014-01-01

    Objective To compare the different concentrations of ropivacaine combined with fentanyl infusion analgesia labor in walking labor analgesia in maternal BP,HR,SpO2,labor,fetal heart,uterine contractions and oxytocin usage and the visual analogue scale (VAS) and maternal motor nerve block.Methods 180 cases of primipara volunteered for labor analgesia,ropivacaine with different concentration of patient controlled epidural analgesia (PCEA),and compared with parturients without analgesia,were randomly divided into group A,group B and group C with 60 cases in each group,three groups were respectively injected into the epidural 0.075% ropivacaine and fentanyl 2 μ g/ml (group A,n=60),0.125% ropivacaine plus fentanyl 2 μ g/ml (group B,n=60),0.20% ropivacaine and fentanyl 2 μ g/ml (group C,n=60).With the cervix opening to the 2-3 cm,L2-3 epidural cephalad catheter,injection of 0.8% lidocaine,5 mins to the load of 8-10 resistant analgesic liquid,confirming the analgesic plane,pain significantly reduced with analgesia pump.Continuous infusion of 6-8 ml,a single push volume of 3 ml,interval time of 15 min,wide open withdrawal.Results The results of three groups of maternal analgesia labor walk at each time point after VAS score was significantly lower with significant difference (P < 0.05); feasible implementation of labor analgesia in group A,group B motor nerve block,in class 0,grade 1,2 cases of group C,and the difference was statistically significant (P < 0.05);additional anesthesia compound liquid of three groups had no significant difference (P > 0.05); there was no significant difference between three groups of maternal mode of delivery and use of oxytocin and neonatal Apgar score (P > 0.05).Conclusion 0.125% ropivacaine + fentanyl was 2 μg/ml continuous infusion for labor analgesia when walk good analgesic effect,motor nerve block light,is worth the clinical promotion.%目的 比较不同浓度罗哌卡因复合芬太尼持续输注在可行走性

  3. A COMPARATIVE STUDY OF POSTOPERATIVE ANALGESIA BY CAUDAL EPIDURAL ROUTE USING BUPIVACAINE WITH TRAMADOL AND BUPIVACAINE WITH FENTANYL IN PAEDIATRIC BELOW UMBILICAL SURGERIES

    Directory of Open Access Journals (Sweden)

    Meera

    2015-05-01

    Full Text Available The aim of this study was to compare the effectiveness of Bupivacaine (0.25% 0.5 ml/kg with Fentanyl 1μg/kg and Bupivacaine (0.25% 0.5 ml/kg with Tramadol 2 mg/kg in caudal block for postoperative analgesia. In the present study, 60 children of ASA I and II, aged between 5-12 years who were scheduled for below umbilical surgical procedures were randomly allotted into 2 groups (30 each to receive either bupivacaine with fentanyl or bupivacaine with tramadol. Caudal block was performed after induction of general anesthesia, no analgesics were given intra-operatively. Postoperative analgesia was evaluated by Numerical Rating Scale and sedation was assessed by five point sedation score. Postoperative analgesia was supplemented with Syrup Paracetamol (10mg/kg when Numerical Rating Scale was 4. Any adverse effect like respiratory depression, urinary retention, nausea and vomiting were recorded in all patients. Caudal tramadol with bupivacaine produced significant increased postoperative analgesia. The duration of analgesia was 861±23 minutes in tramadol with bupivacaine group, as compared to 353.46±31.79 minutes in fentanyl with bupivacaine group. No significant difference found in sedation score in both groups in first hour postoperatively. Two cases in fentanyl with bupivacaine and three cases in tramadol with bupivacaine group developed urinary retention in postoperative period. Four cases in fentanyl with bupivacaine and three cases in tramadol with bupivacaine group developed nausea and vomiting. Our study showed that caudal tramadol with bupivacaine provided longer duration of postoperative analgesia without having significant side effects.

  4. Epidural anesthesia: Views and outcomes of women in labor in a ...

    African Journals Online (AJOL)

    2010-02-08

    Feb 8, 2010 ... There was no difference in the rate of cesarean delivery between them — epidural analgesia. (32% [8/25]) versus .... desaturation was treated with oxygen via a facemask. .... with systemic opioid analgesia is associated with.

  5. Popularizing labor analgesia in China.

    Science.gov (United States)

    Fan, Zi Tian; Gao, Xue Lian; Yang, Hui Xia

    2007-09-01

    In China many women in labor are young primigravidas whose fear of labor pain leads them to request cesarean deliveries. While the rate of cesarean deliveries has reached 50% in many hospitals, less than 1% of women in labor are given neuraxial analgesia. The necessary equipment is seldom available in China and many physicians have misconceptions about the risks associated with neuraxial analgesia, which are low with the ultra-low-dosages used today. However, attitudes have begun to change. Meetings held in China have brought together Chinese physicians and world experts on the various epidural and combined spinal-epidural techniques. Thanks to the information and support provided at these meetings clinical trials were carried out, more than 5000 women benefited from labor analgesia, and publications appeared in Chinese journals. An effective, safe, and cost-effective way to provide analgesia to women in labor may slow the increase in cesarean delivery rates across China and improve women's health in general.

  6. Efficacy of post-operative analgesia after posterior lumbar instrumented fusion for degenerative disc disease: a prospective randomized comparison of epidural catheter and intravenous administration of analgesics

    Directory of Open Access Journals (Sweden)

    Torsten Kluba

    2010-04-01

    Full Text Available This prospective study aimed to compare the efficacy of epidural (EDA versus intravenous (PCA application of analgesics after lumbar fusion. Fifty-two patients scheduled for elective posterior instrumented lumbar fusion were randomized into two groups. EDA patients received an epidural catheter intraoperatively, and administration of ropivacain and sulfentanil was started after a normal post-operative wake-up test in the recovery room area. PCA patients received intravenous opioids in the post-operative period. Differences between EDA and PCA groups in terms of patient satisfaction with respect to pain relief were not significant. Nevertheless, EDA patients reported less pain on the third day after surgery. There were significantly more side effects in the EDA group, including complete reversible loss of sensory function and motor weakness. There were no major side effects, such as infection or persisting neurological deficits, in either group. The routine use of epidural anesthesia for lumbar spine surgery has too many risks and offers very little advantage over PCA.

  7. [Inadvertent epidural infusion of paracetamol].

    Science.gov (United States)

    Charco Roca, L M; Ortiz Sánchez, V E; del Pino Moreno, A L

    2014-10-01

    A 45-year-old woman was accidentally administered an epidural infusion of paracetamol instead of levobupivacaine for postoperative pain therapy during the postoperative period of abdominal hysterectomy under general anesthesia combined with epidural analgesia. The patient had no neurological symptoms at any time, although a slight tendency to arterial hypotension that did not require treatment was observed. No rescue analgesia was necessary until 8h after the start of epidural infusion. The incidence of these types of errors is probably underestimated, although there are several cases reported with various drugs. Copyright © 2013 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved.

  8. The Value of Full Doula Combined with Epidural Analgesia in Natural Childbirth%全程导乐陪伴分娩联合硬膜外镇痛在自然分娩中的应用价值

    Institute of Scientific and Technical Information of China (English)

    刘晓艳

    2014-01-01

    目的:探讨全程导乐陪伴分娩联合硬膜外镇痛在自然分娩中的应用价值。方法:选取2010年1月-2013年6月本院收治的80例足月妊娠产妇,按照随机数字表法将其分为观察组和对照组各40例,观察组给予导乐分娩联合硬膜外镇痛处理,对照组则密切观察产妇产程进行常规方式分娩,比较两组产妇围产期疼痛VAS评分及两组顺产率、胎儿窘迫发生率和新生儿窒息率。结果:观察组第一、二和三产程疼痛VAS评分均明显低于对照组,且观察组顺产率明显高于对照组,胎儿窘迫发生率及新生儿窒息率均明显低于对照组,比较差异均有统计学意义(P<0.05)。结论:全程导乐分娩联合硬膜外镇痛能更好地缓解患者产痛,提高分娩安全性。%Objective:To explore the value of full doula combined with epidural analgesia in natural childbirth.Method:80 cases of maternal were selected in our hospital from January 2010 to June 2013,they were randomly divided into the observation group and the control group,40 cases in each group,the observation group was given the treatment of doula combined with epidural analgesia,the control group was observed the birth process routine methods maternal childbirth,then maternal perinatal pain VAS score and birth rate,incidence of fetal distress and neonatal asphyxia were compared between the two groups.Result:The observation group in the first,second and third stage of labor with pain VAS scores were significantly lower than the control group ,the observation group with birth rate was higher than the control group,the incidence of fetal distress and neonatal asphyxia rate were significantly lower than control group,the differences were statistically significant(P<0.05).Conclusion:Throughout full doula combined with epidural analgesia in natural childbirth,it has better ease labor pain and it can improve labor safety.

  9. Efeitos adversos do sufentanil associado ao anestésico local pelas vias subaracnóidea e peridural em pacientes submetidas à analgesia de parto Efectos adversos del sufentanil asociado al anestésico local por las vías subaracnoidea y peridural en pacientes sometidas a la analgesia de parto Side effects of subarachnoid and epidural sufentanil associated with a local anesthetic in patients undergoing labor analgesia

    Directory of Open Access Journals (Sweden)

    Isabel C.F. Salem

    2007-04-01

    la duración del período de trabajo de parto después de la analgesia, al Apgar de los recién nacidos, a la existencia de hipotensión arterial, bradicardia, náusea, vómito, prurito y retención urinaria. La sedación fue más frecuente en las pacientes de G2, en M1 (50% con diferencia estadística significativa. CONCLUSIONES: El sufentanil en las dosis utilizadas, administrado por vía subaracnoidea o peridural, asociado a los anestésicos locales, determinó similitud en la duración del trabajo de parto después de la analgesia y en el Apgar de los recién nacidos. La sedación fue el efecto adverso más frecuente en las pacientes que recibieron el opioide por vía peridural.BACKGROUND AND OBJECTIVES: The association of an opioid with a local anesthetic improves the quality of labor analgesia and reduces the risk of systemic toxicity of the local anesthetic. However, opioids are not devoid of side effects. The aim of this study was to compare the side effects of subarachnoid sufentanil associated with bupivacaine to those caused by epidural sufentanil associated with ropivacaine in the doses used in the Anesthesiology Department in pregnant women undergoing labor analgesia. METHODS: Sixty pregnant women, ASA physical status I and II, ages between 15 and 42 years, at term and with healthy fetuses, undergoing labor analgesia were enrolled in this study. They were randomly divided in two groups: G1 - combined spinal epidural anesthesia - 0.5% bupivacaine (2.5 mg and subarachnoid sufentanil (5 µg; G2 - Epidural Block - 0.2% ropivacaine (20 mg, and epidural sufentanil (10 µg. Complementary doses of 0.2% ropivacaine (12 mg were administered whenever necessary, and 1% ropivacaine (50 mg was administered for labor resolution. Patients were evaluated after analgesia (M1 regarding the presence of hypotension, maternal bradycardia, pruritus, nausea, vomiting, respiratory depression, and sedation. They were also evaluated postoperatively (M2 regarding the presence of

  10. Effects of epidural analgesia on maternal and infant by vaginal delivery%硬膜外分娩镇痛对经阴道分娩母婴影响的临床研究

    Institute of Scientific and Technical Information of China (English)

    杨絮; 杨泳; 吕国义

    2015-01-01

    目的:探讨硬膜外镇痛对经阴道分娩母婴的安全性和有效性,为临床大范围开展分娩镇痛提供参考依据。方法选取2013年5月至2013年8月非合并其他系统疾病及产科合并症、拟经阴道分娩足月临产孕妇60例,随机分为硬膜外镇痛( EA)组和非镇痛( NA)组,每组30例。入待产室常规监测两组孕妇无创测量血压( NBP)、心率( HR)、脉搏血氧饱和度( SpO2);胎儿娩出即刻采集脐静脉血作血气分析;新生儿出生后1、5、10 min行Apgar评分;记录各产程时间,是否使用缩宫素,宫口扩张至6~7 cm时VAS评分及Bromage评分,产后24 h内出血量,初乳始动时间,新生儿神经行为评分。结果两组孕妇一般资料比较差异未见统计学意义。EA组第一产程和第二产程较NA组延长( P均0.05);EA组新生儿生后1 min/5 min Apgar评分为9.2±0.7/9.2±0.6,低于NA组(9.6±0.5/9.6±0.5,P0.05)。结论本研究所采用硬膜外分娩镇痛方法效果确切,不影响产后泌乳过程,不增加产后出血,不影响产妇下肢活动,对经阴道分娩产妇无不良影响,未见有实际临床意义的新生儿不良影响,对新生儿安全,值得推广。%Objective To investigate the security and effectiveness of epidural analgegia on virginal delivery maternal-neo-nates,in order to provide basis for widely carrying out labor analgesia. Methods Sixty parturient cases in the term of maternal, scheduled for virginal delivery from May to August in 2013,who had no systemic diseases or obstetric complications,were ran-domly divided into epidural analgesia( EA)group and non-analgesia( NA)roup,with 30 cases in each group. In the two groups,gravida with labour signs were sent into labor room,and the values of noninvasive blood pressure( NBP),heart rate ( HR)and pulse oxygen saturation( SpO2 )were recorded. The umbilical venous blood was drawn for blood gas analysis at the

  11. Influencia de los rasgos de personalidad en la percepción del dolor y elección de analgesia durante el parto/Influence of personality traits on pain perception and choice of analgesia during labor

    National Research Council Canada - National Science Library

    J M Caparros Molinero; S Núñez del Moral; M A Soriano Molina

    2014-01-01

      The present study aims to analyze in a group of pregnant women if there is a relationship between personality characteristics, pain perception and the choice whether or not analgesia during labor...

  12. Bloqueio peridural sacral: avaliação da duração da analgesia com o uso associado de lidocaína, fentanil e clonidina Bloqueo peridural sacral: evaluación de la duración de la analgesia con el uso asociado de lidocaína, fentanil y clonidina Epidural caudal block: evaluation of length of analgesia with the association of lidocaine, fentanyl and clonidine

    Directory of Open Access Journals (Sweden)

    Carlos Alberto de Souza Martins

    2004-08-01

    fentanil, grupo III (lidocaína, fentanil y clonidina y grupo IV (lidocaína y clonidina. Se compararon las características de los bloqueos sensitivo y motor. RESULTADOS: No hubo diferencia entre la latencia, bien como en el nivel máximo de bloqueo entre los grupos. La ausencia de bloqueo motor fue el resultado más frecuente, encontrado en cerca de 64% de los pacientes. El intervalo de analgesia fue diferente entre los grupos, siendo más significativo en el grupo III. CONCLUSIONES: El uso de la clonidina, asociada o no al fentanil, prolongó el tiempo de analgesia pós-operatoria en la anestesia peridural sacral con lidocaína.BACKGROUND AND OBJECTIVES: The association of different substances to local anesthetics aims to improve the blockade quality and prolonging analgesia. The aims of this study were to compare the effectiveness of the association of clonidine, clonidine and fentanyl, and fentanyl, to lidocaine for postoperative analgesia. METHODS: Participated in this study 64 patients aged 23 years or above, physical status ASA I or II, undergoing to orificial proctologic surgery under epidural caudal anesthesia. Patients were distributed in 4 groups of 16: group I (lidocaine alone; group II (lidocaine and fentanyl; group III (lidocaine, fentanyl and clonidine; and group IV (lidocaine and clonidine. The quality of sensory and motor blockade were compared. RESULTS: There has been no difference in onset and maximum block level among groups. Absence of motor block was the most frequent result, found in about 64% of patients. Analgesia length was different among groups, being more significant in group III. CONCLUSIONS: Clonidine, associated or not to fentanyl, has prolonged postoperative analgesia after epidural caudal blockade with lidocaine.

  13. Analgesia pós-operatória em correção cirúrgica de pé torto congênito: comparação entre bloqueio nervoso periférico e bloqueio peridural caudal Analgesia postoperatoria en corrección quirúrgica de pie jorobado congénito: comparación entre bloqueo nervioso periférico y bloqueo epidural caudal Postoperative analgesia for the surgical correction of congenital clubfoot: comparison between peripheral nerve block and caudal epidural block

    Directory of Open Access Journals (Sweden)

    Monica Rossi Rodrigues

    2009-12-01

    con dolor postoperatorio intenso. La técnica más utilizada en niños es la epidural caudal asociada a la anestesia general. Posee la limitante de una corta duración de la analgesia postoperatoria. Los bloqueos de nervios periféricos han sido indicados como procedimientos con una baja incidencia de complicaciones y un tiempo prolongado de analgesia. El objetivo del estudio actual, fue comparar el tiempo de analgesia de los bloqueos nerviosos periféricos y del bloqueo caudal y el consumo de morfina, en las primeras 24 horas después de la corrección de PJC en niños. MÉTODO: Estudio randómico doble ciego, en niños sometidos a la intervención quirúrgica para liberación posteromedial de PJC, ubicadas en cuatro grupos conforme a la técnica anestésica: caudal (ACa; bloqueos isquiático y femoral (IF; bloqueos isquiático y safeno (IS; bloqueo isquiático y anestesia local (IL, asociados a la anestesia general. En las primeras 24 horas, los pacientes recibieron dipirona y paracetamol vía oral y fueron evaluados por un anestesiólogo que no conocía la técnica usada. Conforme a las puntuaciones de la escala CHIPPS (Children's and infants postoperative pain scale, se administraba morfina vía oral (0,19 mg.kg-1 por día. RESULTADOS: Fueron estudiados 118 niños distribuidos en los grupos ACa (30, IF (32, IS (28 IL (28. El tiempo promedio entre el bloqueo y la primera dosis de morfina fue de 6,16 horas en el grupo ACa, 7,05 horas en el IF, 7,58 horas en el IS y 8,18 horas en el IL. El consumo de morfina fue de 0,3 mg.kg-1 por día en los cuatro grupos. No hubo diferencia significativa entre los grupos. CONCLUSIONES: Los bloqueos nerviosos periféricos no promovieron un tiempo más elevado de analgesia, ni tampoco una reducción en el consumo de morfina en las primeras 24 horas, en niños sometidos a la corrección de PJC cuando se les comparó con el bloqueo epidural caudal.BACKGROUND AND OBJECTIVES: Correction of congenital clubfoot (CCF is associated with

  14. Comparison of the clinical effect of combined spinal epidural anesthesia and epidural anesthesia for labor analgesia%腰麻联合硬膜外麻醉与硬膜外麻醉用于分娩镇痛的临床效果比较

    Institute of Scientific and Technical Information of China (English)

    陈日亮

    2015-01-01

    目的:比较腰麻联合硬膜外麻醉(CSEA)与硬膜外麻醉(CEA)在分娩镇痛中的临床效果。方法选择2013年12月-2015年1月医院接受分娩镇痛的足月、单胎、头位初产妇60例,根据麻醉方式不同分为腰麻联合硬膜外麻醉(CSEA 组)和单纯硬膜外麻醉(CEA 组)各30例。观察2组孕妇麻醉起效时间、麻醉至手术开始时间、痛觉恢复时间、运动恢复时间、术中孕妇视觉模拟疼痛评分(VAS)、不良反应发生率、新生儿1min Apgar 评分。结果与CEA 组比较,CSEA 组麻醉起效时间、麻醉至手术开始时间较短,而痛觉恢复时间、运动恢复时间及术中孕妇视觉模拟疼痛评分(VAS)长于或优于 CEA 组,比较差异均有统计学意义(P ﹤0.05);2组不良反应发生率以及新生儿1min Ap-gar 评分比较差异无统计学意义(P ﹥0.05)。结论腰麻联合硬膜外麻醉时间短于单纯应用硬膜外麻醉,但恢复时间较长,临床可视患者情况而应用。%Objective To compare the clinical effect of lumbar anesthesia combined with epidural anesthesia (CSEA)and epidural anesthesia(CEA)for labor analgesia. Methods Select 60 cases of pregnant women in labor analgesia. According to different anesthesia,60 cases of pregnant women were divided into CSEA group and CEA group,30 cases in each group. The onset time of anesthesia,the onset time of anesthesia,the recovery time of pain,recovery time of pain,the visual an-alog pain score(VAS),the incidence of adverse reactions,and the Apgar 1min score of neonates were observed in the 2 groups. Results Compared with group CSEA,the onset time of anesthesia,the onset time of anesthesia,the recovery time of pain,recovery time of exercise,and the visual analog pain score(VAS)of pregnant women were significantly higher than those in CEA group,The difference was statistically significant(P ﹤ 0. 05);There was no significant difference in the incidence of

  15. 剖宫产及硬膜外吗啡术后镇痛对产妇泌乳的影响及其护理干预%The Cesarean section and epidural morphine for postoperative analgesia maternal lactation and the influence of nursing intervention

    Institute of Scientific and Technical Information of China (English)

    李彩霞

    2013-01-01

    objective:To observe the cesarean section, epidural morphine postoperative analgesia maternity lactation status and serum prolactin (PRL) change. Methods:The 240 cases of maternal term are divided into four groups: Ⅰ group operation BiHang epidural morphine analgesia; Ⅱ group operation BiHang epidural morphine analgesia, 24 h after additional one time. Ⅲ group do not postoperative analgesia;Vaginal natural childbirth sixty cases of Ⅳ group. 240 cases were performed antenatal, postpartum nursing intervention, scientific propaganda, the maternal and child inmates and pure breastfeeding. Results:Postpartum 5 min, 24 h and h and start within lactation and 72 h lactation hyposecretion incidence and cesarean section group compared with indifference. Conclusion:Due to the nursing intervention, and cesarean section and epidural morphine postoperative analgesia does not affect maternal breastfeeding success rate.%目的:观察剖宫产、硬膜外吗啡术后镇痛产妇的泌乳状况及血清泌乳素(PRL)变化.方法:足月产妇240例均分为四组:Ⅰ组术毕行硬膜外吗啡镇痛;Ⅱ组术毕行硬膜外吗啡镇痛,24h后追加一次;Ⅲ组未行术后镇痛;阴道自然分娩60例为Ⅳ组.240例产妇产前、产后均进行护理干预、科学宣传,实行母婴同室和纯母乳喂养.结果:产后5min、24h及48h内开始泌乳及72h泌乳分泌不足发生率与剖宫产组相比无差异.结论:由于护理干预,剖宫产及硬膜外吗啡术后镇痛不影响产妇母乳喂养的成功率.

  16. 使用硬膜外镇痛分娩与传统分娩产妇焦虑程度的比较研究%The use of epidural analgesia with traditional childbirth puerpera childbirth a comparative study of anxiety

    Institute of Scientific and Technical Information of China (English)

    聂梅; 熊怡

    2015-01-01

    Objective Observed using epidural analgesia childbirth than traditional delivery whether maternal anxiety level is lower, understand labor epidural analgesia effect of interference from the maternal anxiety.Methods Were divided into control group and experimental group, control group of conventional childbirth puerpera, the experimental group for the use of analgesia childbirth puerpera, the two groups of maternal and cesarean section rate compared to the scores of SAS questionnaire. Results Divided the experimental group is significantly higher than control group maternal anxiety group standard (P0.05)。对照组产妇焦虑群体标准均分显著高于实验组(P<0.01)。对照组产妇焦虑发生率显著高于实验组(P<0.01),且对照组产妇剖宫产率显著高于实验组(P<0.01)。结论:使用硬膜外镇痛分娩,可减轻分娩过程中因宫缩引起的疼痛,降低由于疼痛所导致焦虑的程度,提高分娩质量,从而降低剖宫产率。

  17. Catheter-related epidural abscesses -- don't wait for neurological deficits.

    NARCIS (Netherlands)

    Royakkers, A.A.; Willigers, H.; Ven, A.J.A.M. van der; Wilmink, J.T.; Durieux, M.; Kleef, M. van

    2002-01-01

    Epidural abscess is a rare but serious complication of epidural anesthesia for peri- and postoperative analgesia. It is feared because of possible persistent neurological deficits. Epidural abscess presents mostly with a classic triad of symptoms: back pain, fever and variable neurological signs and

  18. Effects of epidural ropivacaine labor analgesia on duration of labor and maternal-fetal%罗哌卡因用于分娩镇痛对产程和母婴的影响

    Institute of Scientific and Technical Information of China (English)

    贾亚楠; 白华; 李明静; 李帆; 孟凡杰

    2014-01-01

    目的:探讨罗哌卡因用于分娩镇痛时对产程和母婴的影响。方法采用回顾性研究的方法,将本院198例产妇分为镇痛组和对照组,观察两组产妇产程、产后2小时出血量及两组新生儿的Apgar评分情况。结果较对照组而言,镇痛组第一产程有所缩短(t=2.343,P<0.05),第二产程有所延长(t=2.391,P<0.05)。两组在产后2小时出血量及两组新生儿的Apgar评分情况上差异无显著性(t=2.343,P>0.05)。结论罗哌卡因用于产妇的镇痛分娩是安全有效的,但实际使用时仍需要结合产妇实际情况,进行合理用药。%Objective To study the effects of epidural ropivacaine labor analgesia on duration of labor and maternal-fetal. Methods 198 maternals from one of third-grade class-A hospital were divided into analgesia group and the control group to observe two groups of maternal labor, postpartum 2 hours blood loss and two groups of neonatal Apgar score by using retrospective study method. Results Compare matched control but speech, the town was painful the set produce a distance to have to shorten in the ifrst (t=2.343, P<0.05) and produce in the second distance up had extension (t = 2.391, P < 0.05). Show differences on nonentity of two sets of the circumstances of Apgar grade points that bleed quantity and two sets of new borns in the postnatal period 2 hours. Conclusion The ropivacaine is a safety because of useding for the pregnant woman's town pain childbearing effective of, but still need to combine a pregnant woman actual circumstance while physically using, carry on reasonable to use a medicine.

  19. Remifentanil em analgesia para o trabalho de parto Remifentanil en analgesia para el trabajo de parto Remifentanil as analgesia for labor

    Directory of Open Access Journals (Sweden)

    Eliane C S Soares

    2010-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: As técnicas neuroaxiais representam atualmente os métodos mais efetivos para controle da dor durante o trabalho de parto e a analgesia peridural utilizando soluções anestésicas ultradiluídas é considerada o padrão ouro, promovendo alívio adequado da dor com mínimos efeitos colaterais. Em algumas situações, no entanto, o emprego dessas técnicas é limitado pela existência de contraindicações maternas ou obstáculos estruturais e materiais. Nestes casos, as opções alternativas ainda são precárias e escassas, oferecendo resultados pouco otimistas e de eficácia questionável. CONTEÚDO: Este artigo apresenta, com base em uma revisão da literatura, as informações disponíveis relacionadas ao emprego do remifentanil como técnica alternativa para a analgesia de parto discutindo aspectos farmacocinéticos, farmacodinâmicos, eficácia analgésica, satisfação materna e efeitos colaterais maternos e fetais. CONCLUSÕES: Os dados iniciais apontam o remifentanil como uma opção promissora a ser empregada nas situações em que a gestante não quer ou não pode receber a analgesia neuroaxial.JUSTIFICATIVA Y OBJETIVOS: Las técnicas neuroaxiales representan actualmente los métodos más efectivos para el control del dolor durante el trabajo de parto, y la analgesia epidural utilizando soluciones anestésicas ultradiluidas se considera el estándar oro, promoviendo el alivio correcto del dolor con los mínimos efectos colaterales. En algunas situaciones, sin embargo, el uso de esas técnicas queda limitado por la existencia de contraindicaciones maternas u obstáculos estructurales y materiales. En esos casos, las alternativas todavía son precarias y escasas, ofreciendo resultados poco optimistas y de una eficacia cuestionable. CONTENIDO: Con base en una revisión de la literatura, este artículo muestra que las informaciones disponibles relacionadas a lo empleo de lo remifetanil como técnica alternativa

  20. Clinical observation of epidural block in metaphase induced labor analgesia%硬膜外阻滞在中期妊娠引产镇痛时机选择的临床观察

    Institute of Scientific and Technical Information of China (English)

    王玥; 康凯; 车向明; 徐铭军

    2014-01-01

    Objective To compare the epidural block in metaphase induced labor at different points of analgesia and its related data. Methods Sixty cases who had termination of pregnancy in our hospital due to unplanned pregnancy or a birth defect were selected and were randomly divided into two groups for epidural block age after conventional treat-ment:group A, in which the anaesthesia was initiated when the maternal had pain, while women in group B had anesthesia (incubation period) after regular contractions began and were treated in the ward for routine treatment. Thirty cases were included in each group. The vital signs, VAS score at each point, motor nerve block classification, induced labor time, blood loss and adverse reactions were recorded before and after analgesia. Results Compared with group B, the VAS score in group A at each point was lower, the labor time was slightly longer and the difference was statistically significant (P 0.05). Conclusion Since it is unnecessary to consider the status of fetus during metaphase induced labor, it is reasonable to start analgesic anaesthesia early. This approach does not increase the frequency of blood loss but the induced labor time is slightly prolonged.%目的:比较硬膜外阻滞在中期妊娠引产不同时点开始镇痛的临床效果。方法选取我院60例因计划外妊娠或有胎儿畸形等妊娠合并症要求终止妊娠者,随机分为两组实施硬膜外阻滞,A组为病房常规处理后产妇有疼痛感即开始实施麻醉,B组为病房常规处理后有规律宫缩开始实施麻醉,每组30例;记录镇痛开始前及镇痛后生命体征、各时点孕妇的VAS评分和运动神经阻滞分级、引产时间、出血量及不良反应情况。结果与B组比较,A组在镇痛后各时点VAS评分降低、引产时间延长,差异均有统计学意义(P<0.05);两组间孕妇引产期间生命体征平稳,出血量及不良反应差异无统计学意义(P>0.05)。

  1. The effects of maternal labour analgesia on the fetus.

    Science.gov (United States)

    Reynolds, Felicity

    2010-06-01

    Maternal labour pain and stress are associated with progressive fetal metabolic acidosis. Systemic opioid analgesia does little to mitigate this stress, but opioids readily cross the placenta and cause fetal-neonatal depression and impair breast feeding. Pethidine remains the most widely used, but alternatives, with the possible exception of remifentanil, have little more to offer. Inhalational analgesia using Entonox is more effective and, being rapidly exhaled by the newborn, is less likely to produce lasting depression. Neuraxial analgesia has maternal physiological and biochemical effects, some of which are potentially detrimental and some favourable to the fetus. Actual neonatal outcome, however, suggests that benefits outweigh detrimental influences. Meta-analysis demonstrates that Apgar score is better after epidural than systemic opioid analgesia, while neonatal acid-base balance is improved by epidural compared to systemic analgesia and even compared to no analgesia. Successful breast feeding is dependent on many factors, therefore randomized trials are required to elucidate the effect of labour analgesia.

  2. 蛛网膜下隙-硬膜外间隙联合阻滞(CSEA)应用于分娩镇痛的临床观察%A CLINICAL STUDY OF COMBINED SPINAL-EPIDURAL ANALGESIA FOR LABOR PAIN

    Institute of Scientific and Technical Information of China (English)

    陈富强; 胡丹; 宋文阁; 付志俭; 艾登斌

    2004-01-01

    目的:研究蛛网膜下隙-硬膜外间隙联合阻滞(Combined Spinal Epidural Analgesia, CSEA)应用于分娩镇痛的临床效果.方法:90例初产妇按入院前后及个人同意分成三组.C组:对照组,未用任何镇痛方法.CEA 组: 0.125%罗哌卡因+2μg /ml芬太尼组.CSEA组:L2/3 CSEA联合穿刺成功后,蛛网膜下腔注入0.17%布比卡因1ml+2.5μg芬太尼1ml,常规向头端置入硬膜外导管.观察产妇的分娩、镇痛情况及镇痛前后对产妇应激及泌乳的影响.结果: 1.CEA组和CSEA组产妇镇痛效果满意,和对照组比较有显著性差异(P0.05),对照组镇痛后比镇痛前的皮质醇含量明显升高,有统计学差异(P0.05).结论:CSEA和CEA都是行之有效的分娩镇痛方法,但CSEA起效迅速、镇痛完善、缩短活跃期产程、不增加器械助产率及剖宫产率,不影响产妇泌乳始动时间,更具有优越性.

  3. Comparison of epidural morphine and morphine combined with ketaming inpostoperative patient contralled analgesia%硬膜外吗啡与吗啡氯胺酮术后病人自控镇痛

    Institute of Scientific and Technical Information of China (English)

    孙艳林; 陈亚军

    2000-01-01

    目的:探讨手术后应用吗啡与吗啡复合氯胺酮行 PCEA 的效果以及氯胺酮对吗啡镇痛作用和不良反应的影响。方法:40 例 ASA 1~2 级择期在腰麻复合硬膜外麻醉下行妇科手术的患者,随机分为单纯吗啡(M)和吗啡复合氯胺酮(KM)两组,每组 20 例,术后连接 GRASEBY9300 型 PCA 泵,镇痛药液中 M 组合吗啡 20mg,KM 组含吗啡 10mg+氯胺酮 100mg。分别于术后 4、8、12、24h 进行随访,记录病人首次按压时间、各时间点视觉模拟评分(VAS)、有效按压次数、不良反应及病人综合满意度。结果:两组患者术后首次按压时间、有效按压次数无显著性差异。吗啡用量 M 组明显高于 KM 组(P<0.05)。所有患者 4、8、12、24h 各时间点 VAS 评分均低于 4 分,且组间比较无显著性差异。M 组患者恶心、呕吐发生率显著高于 KM 组(P<0.05)。两组均未发现有皮肤搔痒。另外两组患者对镇痛效果综合满意度评估优良率为 100%。结论:氯胺酮可以增强吗啡的镇痛作用,减少吗啡用量,降低吗啡不良反应发生率。%Objective: To discuss the effect of epidural morphine and morphine combined with ketamine in PECA, and of ketamine effects on analgesia and side effects of morphine. Methods: 40 patients ASA grade 1~2, under subarachnoid combined with epidural anaesthesia for selective gynaecological surgery were randomly assigned into two groups, morphine group (M) and morphine/ketamine group (KM). At the end of operation, a GRASEBY9300 PCA was connected to the epidural catheter. Analgesic solution contained morphine 20mg in group M and morphine 10mg + ketamine 100mg in group KM. The patients were followed up at 4, 8, 12, 24h after operation and first pressing time, VAS, effective pressing numbers, side effects and patients general satisfactory degree were recorded. Results: First pressing time and effective pressing numbers showed no significantly

  4. A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia

    DEFF Research Database (Denmark)

    Joshi, G.P.; Bonnet, F.; Shah, R.

    2008-01-01

    of the evidence is needed to assess the comparative benefits of alternative techniques, guide clinical practice and identify areas requiring further research. METHODS: In this systematic review of randomized trials we evaluated thoracic epidural, paravertebral, intrathecal, intercostal, and interpleural analgesic...... incidence of hypotension. Paravertebral block reduced the incidence of pulmonary complications compared with systemic analgesia, whereas thoracic epidural analgesia did not. Thoracic epidural analgesia was superior to intrathecal and intercostal techniques, although these were superior to systemic analgesia......; interpleural analgesia was inadequate. CONCLUSIONS: Either thoracic epidural analgesia with LA plus opioid or continuous paravertebral block with LA can be recommended. Where these techniques are not possible, or are contraindicated, intrathecal opioid or intercostal nerve block are recommended despite...

  5. Clinical observation of physiology and psychology of combined spinal and epidural block for total labor course analgesia%全产程腰硬联合阻滞分娩镇痛产妇生理及心理的临床观察

    Institute of Scientific and Technical Information of China (English)

    全伟斌; 周朝明; 劳诚毅; 彭丽; 劳慧娟; 韦洁; 胡兰丹; 曾艳玲

    2011-01-01

    目的 探讨全产程腰硬联合阻滞分娩镇痛对孕妇生理及心理的影响.方法 选择住院分娩孕妇160例,按知情同意、自主选择的方法,随机分为观察组和对照组各80例.观察组实施全产程腰硬联合阻滞分娩镇痛,对照组未实施分娩镇痛,比较两组孕妇的焦虑程度、镇痛效果、产程时间、产后出血、分娩方式和Apgar评分等.结果 两组孕妇的焦虑程度、镇痛效果、产程时间、剖宫产率等情况比较差异有显著性(P<0.05).结论 实施全产程腰硬联合阻滞分娩镇痛,可缓解孕妇焦虑情绪,缩短产程,降低剖宫产率,对孕妇和新生儿无不良影响.%Objective To investigate the affect of physiology and psychology of combined spinal and epidural block for total labor course analgesia. Methods 160 gravidas were randomly divided into Treated Group (80 cases) and Control Group (80 cases). Treated Group received combined spinal and epidural block for total labor course analgesia, while Control Group did nothing. The anxiety level, effect of analgesia, time of labor course, volume of postpartum hemorrhage,mode of delivery and Apgar scores were analyzed. Results The anxiety level, effect of analgesia, time of labor course,cesarean section rate in both groups were statistically different ( P<0. 05 ). Conclusion Combined spinal and epidural block for total labor course analgesia can ease anxiety, decrease the time of labor course and cesarean section rate, while there aren,t adverse effects to gravidas and neonates.

  6. Comparison of the Effects of General Anesthesia and Epidural Combined Anesthesia on Postoperative Early Cognitive Function in Elderly Patients with Postoperative Epidural Analgesia%全身麻醉与硬膜外复合麻醉继以术后硬膜外镇痛对老年患者非心脏手术后早期认知功能的影响比较

    Institute of Scientific and Technical Information of China (English)

    隋金玲; 邓蓉蓉

    2015-01-01

    Objective To probe into the effect of general anesthesia and epidural combined anesthesia on postoperative early cognitive function in elderly patients with postoperative epidural analgesia. Methods 115 patients who accepted heart operation treatments in our hospital from January, 2011 to December, 2014 and these patients were randomly divided into the control group and the observation group.In the observation group of 60 patients were received general anesthesia and epidural combined anesthesia and postoperative epidural analgesia while in the control group of 55 patients were received general anesthesia and intravenous analgesia after surgery. Then, the postoperative neurological and mental function and other indicators of two groups of patients were observed and the early postoperative cognitive function of patients was comparative analyzed.Results The incidence of cognitive dysfunction seven days after surgery in the observation group and control group was 51.67% (31/60) and 49.09% (27/55).Conclusion After non cardiac surgery, the elderly patient wil have some early cognitive dysfunction due to surgical operation and education, while the effect of epidural anesthesia and epidural anesthesia on early cognitive function in elderly patients is not obvious.%目的:探讨全身麻醉与硬膜外复合麻醉继以术后硬膜外镇痛对老年患者非心脏手术后早期认知功能的影响。方法选择2011年01月~2014年12月在我院进行非心脏手术的老年患者115例分为对照组和观察组,观察组60例患者接受全身麻醉与硬膜外复合麻醉和术后硬膜外镇痛,对照组55例患者仅接受全身麻醉和术后静脉镇痛。观察两组患者术后神经及精神功能等各项指标,就患者术后早期认知功能情况作对比分析。结果观察组和对照组患者在术后七天的认知功能障碍发生率为51.67%(31/60)、49.09%(27/55)。结论在进行非心脏手术后,老年患者会因外科手

  7. Pain relief and clinical outcome: from opioids to balanced analgesia

    DEFF Research Database (Denmark)

    Kehlet, H

    1996-01-01

    If it is generally accepted that adequate postoperative pain relief will improve outcome from surgery, several controlled trials demonstrated this only for lower body surgical procedures with epidural and spinal anesthetics. Important effects on outcome were not shown when postoperative opioids...... were administered with patient controlled (PCA) or epidural techniques. However, the most optimal pain relief seems to be best achieved with balanced analgesia techniques using combinations of epidural opioids and local anesthetics and systemic non-steroidal antiinflammatory drugs. Future efforts...

  8. Progress in analgesia for labor: focus on neuraxial blocks

    Directory of Open Access Journals (Sweden)

    J Sudharma Ranasinghe

    2009-05-01

    Full Text Available J Sudharma Ranasinghe, David J BirnbachMiller School of Medicine, University of Miami, Florida, USAAbstract: Neuraxial analgesia is widely accepted as the most effective and the least depressant method of providing pain relief in labor. Over the last several decades neuraxial labor analgesia techniques and medications have progressed to the point now where they provide high quality pain relief with minimal side effects to both the mother and the fetus while maximizing the maternal autonomy possible for the parturient receiving neuraxial analgesia. The introduction of the combined spinal epidural technique for labor has allowed for the rapid onset of analgesia with minimal motor blockade, therefore allowing the comfortable parturient to ambulate. Patient-controlled epidural analgesia techniques have evolved to allow for more flexible analgesia that is tailored to the individual needs of the parturient and effective throughout the different phases of labor. Computer integrated systems have been studied to provide seamless analgesia from induction of neuraxial block to delivery. New adjuvant drugs that improve the effectiveness of neuraxial labor analgesia while decreasing the side effects that may occur due to high dose of a single drug are likely to be added to future labor analgesia practice. Bupivacaine still remains a popular choice of local anesthetic for labor analgesia. New local anesthetics with less cardiotoxicity have been introduced, but their cost effectiveness in the current labor analgesia practice has been questioned.Keywords: labor, neuraxial, analgesia, neuraxial labor analgesia

  9. 分娩镇痛后产妇血清IL-6、IL-8、IL-10的变化%Effect of analgesia with continued epidural block on the serum IL-6, IL-8 and IL-10 in parturients

    Institute of Scientific and Technical Information of China (English)

    修玉芳; 黄东林; 王颖; 肖龙

    2013-01-01

    目的:观察罗哌卡因连续硬膜外阻滞进行分娩镇痛对产妇血清中IL-6、IL-8、IL-10的影响.方法:将200例产妇随机分为观察组和对照组各100例.观察组在宫口开至2 ~3 cm时,开始采用连续硬膜外阻滞进行分娩镇痛;对照组按产科常规处理.观察两组产妇分娩镇痛前30 min、分娩镇痛后2h、分娩后24 h、48 h和72 h等5个时点的IL-6、IL-8、IL-10水平的变化.结果:两组产妇分娩镇痛后血清IL-6、IL-8、IL-10水平与分娩镇痛前比较均有升高(P<0.01),且多在分娩后24 h达峰值,对照组较观察组升高更为明显(P<0.05).结论:罗哌卡因连续硬膜外阻滞进行分娩镇痛可有效降低产妇分娩后炎性应激反应.%Objective:To observe the effect of labor analgesia with continued epidural block on the serum IL-6,IL-8 and IL-10 in parturients.Methods:Two hundreds of labor women were divided into two groups with 100 cases each group.One hundred parturients were selected as labor analgesia group (group I) and the others were as nature delivery group without analgesia (group II).Analgesia was used when utero-cervical was opened to 2 ~ 3 cm.The levels of serum IL-6,IL-8 and IL-10 were observed at five time points:before labor analgesia,at 2 h after the labor analgesia,at 24,48,72 h after delivery.Results:The levels of serum IL-6,IL-8 and IL-10 were increased significantly after labor analgesia,reached at peak values at 24 h (P < 0.05),and then gradually declined but still higher than the baseline values.The serum IL-6,IL-8 and IL-10 were significantly higher at 2 and 24 h in group Ⅱ than those in group I (P < 0.05).Conclusion:Labor analgesia with continued epidural block is safe and effective.Epidural analgesia can reduce the level of serum IL-6,IL-8 and IL-10 and inflammatory response during delivery.

  10. Neuropatía periférica tras el parto: Implicaciones de la anestesia epidural Peripheral neuropathy after delivery implications for epidural anaesthesia

    Directory of Open Access Journals (Sweden)

    S. Velázquez

    2006-05-01

    Full Text Available La incidencia de lesiones neurológicas de miembros inferiores en la práctica obstétrica es del 0,08% y 0,92%. La incidencia de complicaciones neurológicas asociadas a la técnica epidural ha sido estimada en 2 casos de cada 10.000 epidurales. Durante los últimos años, con la generalización de la analgesia epidural para el trabajo de parto, es posible que algunas de las neuropatías sean atribuidas a esta técnica, olvidando que hay otros mecanismos de lesión en estas situaciones. Presentamos el caso de una paciente primigesta de 21 años de edad y 139 cm de altura sin antecedentes de interés, que 24 horas tras una epidural para parto y un expulsivo prolongado resuelto con fórceps, desarrolla un "pie caído", que evolucionó a la resolución funcional completa. El pie caído puede darse como consecuencia de una lesión del nervio peroneo, del ciático, o de una raíz del plexo lumbo-sacro. La clínica unida al uso de pruebas como la resonancia magnética (RNM y el electromiograma (EMG, ayudan en el diagnóstico diferencial de la lesión. Parece necesario el estudio del las neuropatías relacionadas con el parto para descartar su relación con la técnica anestésica empleada. Con frecuencia, estas lesiones se deben a mecanismos ajenos a la analgesia-anestesia epidural, si bien debemos procurar minimizar su incidencia con la realización de punciones a niveles adecuados, evitando la inyección de anestésicos cuando existen parestesias, valorando los factores de riesgo en obstetricia y, una vez producida la lesión, con un seguimiento clínico estrecho.Postpartum neurological damage occurs in the obstetric practice with an incidence between 0.08-0.92%. Neurological damage secondary to epidural technique is about 2:10,000. In last years, epidural anesthesia has become a generalized practice in obstetrics. Because of it, sometimes, the postpartum neurological damage can be attributed to epidural analgesia, forgetting other mechanisms. We

  11. Sufentanil versus Fentanyl for Postoperative Patient-Controlled Epidural Analgesia:A Systematic Review%舒芬太尼与芬太尼用于术后硬膜外自控镇痛的系统评价

    Institute of Scientific and Technical Information of China (English)

    唐轶洋; 张兴安; 阳婷婷; 徐波

    2012-01-01

    Objective To systematically evaluate effectiveness, dosage and adverse reaction of sufentanil versus fentanyl for postoperative patient-controlled epidural analgesia (PCEA), so as to provide evidence for rational drug use in clinic. Methods Databases including The Cochrane Library, the special trials registered in the Cochrane anesthesia group, MEDLINE, EMbase, CBM, CNKI, VIP and WanFang Data were searched by the end of 2012, and the relevant periodicals were also manually searched to collect the randomized controlled trials (RCTs) on sufentanil versus fentanyl for postoperative patient-controlled epidural analgesia. According to the Cochrane Handbook 5.0, literature was screened, data were extracted, and quality of the included studies was critically assessed. Then meta-analysis was performed using RevMan 5.1 software. Results A total of 25 RCTs involving 1 944 patients were included. The results of meta-analyses showed that: a) as for visual analog scale (VAS), compared with the fentanyl group, the postoperative VAS at 2-hour, 4-hour, 8-hour, 12-hour, 24-hour and 48-hour was decreased in the sufentanil group; b) as for sedation scale, the fentanyl group, the postoperative sedation at 12-hour and 24-hour was lower in the sufentanil group when adopting 0 to 3 points scoring method, but there were no significant differences at other time points; c) as for drug dosage, compared with the fentanyl group, the postoperative drug consumption at 24-hour and 48-hour was less in the sufentanil group; d) as for adverse reaction, the incidence of postoperative nausea, vomiting, dizziness and somnolence in the sufentanil group was lower than those in the fentanyl group. But there was no significant difference in other adverse reactions such as skin itching, limbs numbness and motor disturbance between the two groups; and e) as for the demands of additional analgesic drugs, compared with the fentanyl group, the incidence of demanding additional analgesic drugs was lower in the

  12. 硬膜外自控镇痛泵防治前列腺术后膀胱痉挛失败原因分析%Analysis of the failure causes of bladder spasm of patient-controlled epidural analgesia pump treatment after prostatectomy

    Institute of Scientific and Technical Information of China (English)

    刘华平; 张欲晓; 张继邦; 黄永斌; 张海涛

    2013-01-01

    目的:观察硬膜外自控镇痛泵(PCEA)防治前列腺术后膀胱痉挛的失败原因,探讨补救措施。方法总结10年来PCEA防治前列腺术后膀胱痉挛的临床资料,分析PCEA防治前列腺术后膀胱痉挛的失败原因。结果本组11例,2例自控泵电源不足,3例硬膜外导管滑脱,1例导管阻塞,1例接头漏液,3例麻药配方剂量不足,1例硬膜外腔粘连。以上问题出现分别予以更换电池、静脉自控泵镇痛、更换三通管接头和应用盐酸屈他维林以补救。11例均达到防治膀胱痉挛的满意效果,未出现严重血尿和术后切口感染等严重并发症。结论 PCEA防治前列腺术后膀胱痉挛效果肯定,一旦发现术后镇痛效果不佳,及时分析原因,并予以纠正或采取其他方法防止膀胱痉挛,以免引起出血、感染等严重并发症。%Objective To investigate the failure causes and remedial measures of bladder spasm of patient-controlled epidural analgesia pump treatment after prostatectomy. Methods Clinical data of patient who received controlled epidural analgesia pump treatment of bladder spasm after prostatectomy in last ten years were summarized and reviewed retrospectively, andthe failure causes for bladder spasm of patient-controlled epidural analgesia pump treatment after prostatectomy were analzed. Results The group of 11 cases, 2 cases of controlled pump power supply, 3 cases of epidural catheter slippage, catheter obstruction in 1 cases, 1 cases of joint leakage, 3 cases of deficiency of anesthetic dose formula, 1 cases of epidural adhesion. All of the above problems are to replace the battery, patient-controlled intravenous analgesia, joint replacement and application of three pipe Drotaverine to remedy. All 11 cases achieved satisfactory effect in the prevention of bladder spasm, no severe hematuria and serious complication after incision infection. Conclusion Sure of bladder spasm after prostatectomy PCEA

  13. No evidence of a clinically important effect of adding local infusion analgesia administrated through a catheter in pain treatment after total hip arthroplasty

    DEFF Research Database (Denmark)

    Specht, Kirsten; Leonhardt, Jane Schwartz; Revald, Peter

    2011-01-01

    Background and purpose Postoperative analgesia after primary total hip arthroplasty (THA) using opioids is associated with troublesome side effects such as nausea and dizziness, and epidural analgesic means delayed mobilization. Thus, local infiltration analgesia (LIA) during surgery prolonged...

  14. 硬膜外镇痛和静脉镇痛对脊柱融合术后镇痛效果比较的Meta分析%Comparison of the analgesic efficacy between the epidural and intravenous analgesia after spinal fusion:a Meta-analysis

    Institute of Scientific and Technical Information of China (English)

    梁林; 姜为民

    2014-01-01

    Objectives: To compare the efficacy of patient-controlled epidural analgesia and patient-controlled intravenous analgesia in postoperative analgesia after spinal fusion. Methods: The CNKI, Wanfang, CBM, Pubmed, Embase, Ovid, Cochrane library databases were searched by computer. The randomized controlled trails with patient-controlled epidural analgesia or patient-controlled intravenous analgesia after spinal fusion published from May 1985 to July 2013 were selected. All of them were assessed by the standard of Cochrane systematic review. Data of postoperative VAS and the rate of side effects after using the analgesic drugs were extracted into an electrical sheet, which was synthesized by a Meta-analysis with RevMan 5.2 software. Re-sult: Eight randomized controlled trails involving 482 patients met the inclusion criteria. And the quality grade of 3 literatures was A, 5 literatures was B. The result of meta-analysis showed that: ①Visual analogue score(VAS). The postoperative first day′s VAS[WMD=-0.47, 95%CI(-0.74, -0.20)], second day′s VAS[WMD=-0.66, 95%CI(-1.14, -0.19)] showed that the patient-controlled epidural analgesia had a good analgesic effect compared with the patient-controlled intravenous analgesia, and both had statistic differences(P0.05); ②The side effects. The patient-controlled epidural analgesia had a higher incidence of skin itch[RR=1.53, 95%CI(1.08, 2.16)], paresthesia[RR=3.34, 95%CI(1.12, 9.98)] after surgery than the patient-controlled intravenous analgesia, and both had statistic differences(P0.05). Conclusions: The patient-controlled epidural analgesia has better analgesic effects on the postoperative first and second day after spinal fusion, but obviously has a high-er incidence of skin itch and paresthesia than the patient-controlled intravenous analgesia.%目的:采用Meta分析方法比较硬膜外镇痛和静脉镇痛两种自控镇痛方式对脊柱融合术后的镇痛效果。方法:计算机检索中国知网、万方数

  15. Comparação de morfina administrada por via intravenosa e via epidural com/sem bupivacaína ou ropivacaína no tratamento da dor pós-toracotomia com a técnica de analgesia controlada pelo paciente Comparación de la morfina administrada por vía intravenosa y vía epidural con /sin bupivacaína o ropivacaína en el tratamiento del dolor pos toracotomía con la técnica de analgesia controlada por el paciente Comparison of intravenous morphine, epidural morphine with/without bupivacaine or ropivacaine in postthoracotomy pain management with patient controlled analgesia technique

    Directory of Open Access Journals (Sweden)

    Esra Mercanoğlu

    2013-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O objetivo deste estudo randomizado, duplo-cego e prospectivo foi determinar a eficácia e os efeitos colaterais da administração por via intravenosa ou epidural de morfina, bupivacaína ou ropivacaína no tratamento da dor pós-toracotomia. MÉTODOS: Sessenta pacientes submetidos a procedimentos de toracotomia eletiva foram randomicamente alocados em quatro grupos com o uso da técnica de envelopes lacrados. Os grupos MIV, ME, MEB e MER receberam morfina controlada pelo paciente por via intravenosa, e morfina, morfina-bupivacaína e morfina- ropivacaína epidural, respectivamente. Frequência cardíaca, pressão arterial e saturação de oxigênio perioperatórias e dor pós-operatória em repouso e durante a tosse, efeitos colaterais e necessidade de analgésicos de resgate foram registrados aos 30 e 60 minutos e em duas, quatro, seis, 12, 24, 36, 48 e 72 horas. RESULTADOS: A necessidade de sódio diclofenaco durante o estudo foi menor no grupo ME. A área sob a curva de tempo na VAS foi menor no grupo ME em comparação com o Grupo MIV, mas similar aos Grupos MEB e MER. Os escores de dor em repouso foram maiores nos tempos 12, 24, 36 e 48 horas no Grupo MIV em comparação com o Grupo ME. Os escores de dor em repouso foram maiores aos 30 e 60 minutos nos Grupos ME e MIV em comparação com o Grupo MEB. Os escores de dor durante a tosse aos 30 minutos foram maiores no grupo ME em comparação com o Grupo MEB. Não houve diferença entre os Grupos MIV e MER. CONCLUSÕES: Morfina administrada por via epidural foi mais eficaz do que por via intravenosa. A eficácia foi maior no grupo EM no período pós-operatório tardio e no Grupo MEB no período pós-operatório inicial. Concluímos que morfina administrada por via epidural foi a mais eficaz e preferida.JUSTIFICATIVA Y OBJETIVOS: El objetivo de este estudio aleatorio, doble ciego y prospectivo fue determinar la eficacia y los efectos colaterales de la administraci

  16. Headache and seizures after cervical epidural injection in a patient undergoing coronary artery bypass grafting

    Directory of Open Access Journals (Sweden)

    Dheeraj Arora

    2012-01-01

    Full Text Available Epidural analgesia is widely used in cardiothoracic surgery. Most of the complications associated with epidural analgesia are related to the insertion techniques of epidural catheter. A 68-year-old obese patient posted for coronary artery bypass grafting surgery developed headache followed by seizures after insertion of the thoracic epidural catheter. Magnetic resonance imaging revealed air in the basal cisterns and in the left frontal region. The patient was managed conservatively and the symptoms subsided after 24 h. Later, the patient underwent coronary angioplasty.

  17. 自控硬膜外镇痛用于腹部手术后病人的护理评价%Nursing evaluation on patients with patient control epidural analge-sia after abdominal surgery

    Institute of Scientific and Technical Information of China (English)

    赵泽芹; 孙学君; 周承孝

    2008-01-01

    Objective To evaluate the effects of patient control epidural analgesia (PCEA) on analge-sia,sedation.Psychology,HR,BP and life quality in patients after abdominal surgery.Methods Patients were consecutively randomized in to analgesia group (n=70) in which PCEA were used,analgesic solution (0.5% bubivacaine 20 ml,fentany 10.4 mg,ondansetron 8 mg diluted to 100 ml with 0.9% NaCl) were continuously infusion in to epidural Cavity with electronic pump; Those patients without PCEA were control group (n=70),VAS,Ramsay sedation scal and changes of BP,HR were monitor in 2,6,10,16,24 h post operation and SAS.SDS were investigate before operation and 2d after surgery respectively.Simultaneously.The life quality and dependence with nurse were observation by nurses.Results All patients in analgesic group presented the best an-algesic sedation efficacy,VAS scores < 1,Ramsay sedation scale in between 2.1~3.2,SAD (40.6),SDS (39.8) post operation were significantly less than SAD (42.5),SDS (42.8) before operation (P < 0.05),BP,HR were reladve stability at various time points,life quality have been obviously improved; In the control group,VAS scores.Ramsay scale were 4.70,Ramsay sedation scale in between 0.89~1.22,the SAS (44.5),SDS (43.8) of post operation were oberviously increase (P<0.05) than before operation,HR were increased in various time point expertly 2 h post operation and there were severe anxious reaction have been obser-vation,wheares patient life quality dependence were reduction than analgesic group.There were significantly difference (P<0.05) for VAS Ramsay sedation seal and SAS.SDS between two groups compared in various time points after surgery (except 2 h post operation).Conclusion PCEA may be provided effective postoperative an-algesia,reduce psychological reaction,and improve life quality,in which beneficial for patient recovery.%目的 对采用自控硬膜外镇痛病人的镇痛镇静效果及心理学变化等进行评价.方法 随机选择施行腹

  18. Pleural puncture with thoracic epidural: A rare complication?

    Directory of Open Access Journals (Sweden)

    Rachna Wadhwa

    2011-01-01

    Full Text Available Freedom from pain has almost developed to be a fundamental human right. Providing pain relief via epidural catheters in thoracic and upper abdominal surgeries is widely accepted. Pain relief through this technique not only provides continuous analgesia but also reduces post-operative pulmonary complications and also hastens recovery. But being a blind procedure it is accompanied by certain complications. Hypotension, dura puncture, high epidural, total spinal, epidural haematoma, spinal cord injury and infection are some of the documented side effects of epidural block. There are case reports eliciting neurological complications, catheter site infections, paresthesias, radicular symptoms and worsening of previous neurological conditions. Few technical problems related to breakage of epidural catheter are also mentioned in the literature. The patient had no sequelae on long term follow up even when a portion of catheter was retained. We present a case report where epidural catheter punctured pleura in a patient undergoing thoracotomy for carcinoma oesophagus.

  19. Analysis of 108 cases of anesthesia for labor analgesia with ropivacaine epidural fentanyl%罗呱卡因联合芬太尼硬膜外阻滞麻醉用于分娩镇痛108例分析

    Institute of Scientific and Technical Information of China (English)

    李丽; 孙建群

    2014-01-01

    Objective To investigate the ropivacaine epidural anesthesia combined with fentanyl analgesia effect and the impact on the safety of mother and child,the incubation period to analyze the feasibility of labor analgesia.Methods Voluntary requirements of lumbar epidural anesthesia for labor analgesia of 108 cases of women in the observation group,did not implement the same period 100 cases of mater-nal pain control group.Comparison of two maternity analgesia,duration of labor,use of oxytocin,neonatal asphyxia,and postpartum hemor-rhage.Analgesic timing of different latencies group active phase group were compared childbirth labor time,oxytocin use,neonatal asphyxia, and postpartum hemorrhage.Results The visual analog scale (Visual analogue scale,VAS)scores were significantly lower than the control group (P0.05);between the timing of different analgesic latencies group and active group of neo-natal asphyxia,postpartum hemorrhage,duration of labor was not statistically significant (P>0.05).Conclusion Ropivacaine fentanyl an-algesia epidural anesthesia effect is good,no adverse effects on mother and child,the incubation period analgesia feasible to meet the needs of the entire production process,is worthy of further promotion.%目的:探讨罗呱卡因联合芬太尼硬膜外阻滞麻醉分娩镇痛的效果及对母儿安全性的影响,潜伏期进行分娩镇痛可行性的分析。方法选择自愿要求硬膜外阻滞麻醉分娩镇痛的108例产妇为观察组,同期未实施镇痛的100例产妇为对照组。比较两组产妇分娩镇痛效果、产程时间、催产素使用、新生儿窒息及产后出血情况。镇痛时机的选择不同的潜伏期组与活跃期组,比较两组分娩产程时间、催产素使用、新生儿窒息及产后出血情况。结果观察组视觉模拟评分明显低于对照组(P<0.05),但增加催产素使用率(P<0.05);两组新生儿窒息、产后出血、产程时间比较差异无统计

  20. Cronobiología en anestesia epidural Obstétrica: Efecto de la noche sobre el índice de complicaciones Cronobiology in obstetric epidural anesthesia: consequences of the sleep deprivation among anestresiologist in the complications rate

    Directory of Open Access Journals (Sweden)

    F. Martínez-Jiménez

    2006-03-01

    Full Text Available Introducción: Los efectos del trabajo continuado y nocturno sobre la atención y la incidencia de complicaciones en desarrollo habitual de las labores del médico han sido previamente estudiados, aunque con resultados poco concluyentes. Objetivo: Comparar la incidencia de complicaciones, durante la punción, en el curso del bloqueo, como consecuencia de una analgesia incompleta y evaluar las diferencias que existen entre el día y la noche definiendo día como el periodo entre 9:00 y 21:59 h y noche: de 22:00 a 8:59 h. Material y métodos: Hemos realizado un estudio de los bloqueos recogidos en nuestra base de datos informatizada de pacientes a quienes se practicó algún bloqueo central para analgesia del parto realizados en un hospital universitario de grado 4, con atención durante las 24 horas, durante un periodo de 2 meses. Resultados: Se ha estudiado un total de 1097 pacientes, homogéneas en su distribución (variables demográficas y obstétricas, entre el día y la noche. El número de pacientes a las que se les practica un bloqueo analgésico para trabajo de parto no muestra diferencias entre el día y la noche. No hemos encontrado diferencias en la incidencia de complicaciones en la punción ni de analgesia incompleta, deficiente o necesidad de re-punción. Conclusiones: Parece que el cansancio o la falta de sueño no influyen en la incidencia de complicaciones en la analgesia para el trabajo de parto en una unidad de atención las 24 horas. Probablemente, los médicos se ven incentivados por la realización de una tarea interesante.Introduction: Sleep deprivation effects in vigilance, performance and complications have been previously studied in general population and in medical tasks too. Results from these studies weren’t definitive. Aim: Our objective is to compare the number of complications during the epidural puncture itself, (haematic, paresthesias, accidental dural puncture and others during the analgesia period (lateral

  1. Ocorrência de hematoma peridural após anestesia geral associada à analgesia pós-operatória com cateter peridural em paciente em uso de heparina de baixo peso molecular: relato de caso Ocurrencia de hematoma postanestesia general asociada a analgesia postoperatoria con cateter peridural en paciente que usa heparina de bajo peso molecular: relato de caso Epidural hematoma after general anesthesia associated with postoperative analgesia with epidural catheter in patient using low molecular weight heparin: case report

    Directory of Open Access Journals (Sweden)

    Ranger Cavalcante da Silva

    2006-04-01

    drenaje del hematoma la paciente recuperó gradualmente la fuerza en los miembros inferiores, recibió alta en diez días con cuadro de disfunción de esfínteres. Después de tres meses el cuadro remitió y no hubo secuela neurológica definitiva. CONCLUSIONES: El rápido diagnóstico con intervención quirúrgica precoz es el tratamiento más eficaz para la reducción de la lesión neurológica, en pacientes que desarrollan hematoma peridural postoperatorio. La utilización de heparina de bajo peso molecular, con uso actual de catéter peridural, exige la adhesión estricta a protocolos establecidos, para que se reduzcan los riesgos del desarrollo de hematoma peridural.BACKGROUND AND OBJECTIVES: Presents a patient case with epidural hematoma, in the course of the use of epidural catheter and low molecular weight heparin, her clinical condition and treatment. CASE REPORT: A 75-year old female patient, submitted to the fixation of lumbar spine by anterior route, who, in the postoperative period, developed a clinical condition of progressive paralysis of the lower limbs, with loss of sensitivity and presenting no intense radicular pain. The treatment was the immediate medullar decompression, with drainage and surgical cleaning of a epidural hematoma, which extended from the 5th to the 10th thoracic vertebrae. After the drainage of the hematoma, the patient gradually recovered the strength in the lower limbs, was discharged in ten days with a condition of sphincterian dysfunction. After three months, the condition receded and there was no definitive neurological sequel. CONCLUSIONS: The quick diagnosis with early surgical intervention is the most effective treatment for the reduction of neurological damage, in patients that develop postoperative epidural hematoma. The use of low molecular weight heparin, in the course of the use of epidural catheter, requires the strict compliance with the established protocols so that the risks of epidural hematoma development can be

  2. The comparative study of epidural levobupivacaine and bupivacaine in major abdominal surgeries

    Directory of Open Access Journals (Sweden)

    Ali Uzuner

    2011-01-01

    Conclusions: The results of our study suggest that same concentration of epidural levobupivacaine and bupivacaine with fentanyl provide stable postoperative analgesia and both were found safe for the patients undergoing major abdominal surgery.

  3. Epidural anesthesia: Views and outcomes of women in labor in a ...

    African Journals Online (AJOL)

    Epidural anesthesia: Views and outcomes of women in labor in a Nigerian ... childbirth is a well known cause of dissatisfaction amongst women in labor. ... analgesia in labor is becoming widespread due to its benefit in terms of pain relief.

  4. 改良埋入式注射泵联合硬膜外自控镇痛在晚期癌痛的疗效观察%Analgesic effect of Modified Embedded Injection Pump Combined with Patient-controlled Epidural Analgesia Pump with Late Cancer Pain

    Institute of Scientific and Technical Information of China (English)

    何敏琪; 周瑞仁

    2011-01-01

    目的 观察改良埋入式注射泵联合硬膜外自控镇痛(PCEA)对晚期癌痛患者的镇痛效果.方法 晚期癌痛患者25例,用改良埋入式注射泵植入皮下疏松结缔组织连接大容量镇痛泵持续注药止痛.药物配方:0.125%盐酸罗哌卡因、0.0002%芬太尼、0.0125%地塞米松、0.003%氟哌啶,流量1 ml/h-1,PCA 0.5 ml/30 min-1.结果 25例患者治疗前后VAS评分比较差异具有统计学意义(P<0.05),镇痛满意程度优良率84%~96%,患者生命体征稳定.结论 改良埋入式注射泵联合硬膜外自控镇痛术治疗于晚期癌痛安全有效.%Objective To observe the analgesia effect of modified embedded injection pump combined with patient-controlled epidural analgesia in 25 patients with late cancer pain. Methods Modified embedded injection pump ,which implanted under the skin loose connective tissue connect big capacity analgesia pump continue inject drugs to reduce pain. Drug composition: 0. 125% ropivacaine, 0. 0002% fentanyl, 0. 0125% dexamethasone, and 0. 0125% droperidol. The continuous was 1 ml per hour,0.5 ml per 30 minutes, respectively. Results The VAS scores before and after treatment were significantly different( P< 0.05 ). The good or excellent rate was 84% - 96%for satisfaction degree evaluation. Patient's vital signs were stability. Conclusion Modified embedded injection pump combined with patient-controlled epidural analgesia provide a safe and effective method for late cancer pain treatment.

  5. 天枢穴药物敷贴联合硬膜外镇痛泵对痔疮术后疼痛患者VAS评分及血清β-内啡肽的影响%Effect of VAS Score and Serumβ-endorphin on Post-operation Pain of Hemorrhoids by Application at Tianshu Combined with Epidural Analgesia Pump

    Institute of Scientific and Technical Information of China (English)

    洪顺垣

    2016-01-01

    Objective:To observe the effect of VAS score and serum β-endorphin on post -operation pain of hemorrhoids by application at Tianshu combined with epidural analgesia pump .Methods:Sixty cases were ran-domly divided into a treatment group and a control group ,with thirty cases in each group .The treatment group received the application at tianshu combined with epidural analgesia pump ,and the control group received epi-dural analgesia pump .Both groups received the postoperative routine treatment .Their VAS score and serum β-endorphin were observed and analyzed comparatively .Results:The VAS score of both groups were increased in 2 h,6 h,24 h,48 h after haemorrhoidectomy compared with that 30 minutes before haemorrhoidectomy ( P 0 .05 );the serum β-endorphin of both groups was descended in 24 h,48 h after haemorrhoidectomy .The treatment group was higher than the control group ,and there was a statistical difference between two groups ( P<0 .05 ) .Conclusion:Application at Tianshu combined with epi-dural analgesia pump can effectively relieve post -operation pain of hemorrhoids ,and its mechanism may be re-lated to the increase of serum β-endorphin .%目的:探讨天枢穴药物敷贴联合硬膜外镇痛泵对痔疮术后疼痛患者VAS评分及血清β-内啡肽的影响。方法:将60例患者按随机数字表法分为观察组和对照组,每组30例。观察组予天枢穴药物敷贴联合硬膜外镇痛泵,对照组予硬膜外镇痛泵,且两组术后予常规处理。观察治疗前后的VAS评分及血清β-内啡肽含量,进行对比分析。结果:术后2 h、6 h、24 h、48 h两组的VAS评分较本组术前30 min均升高(P<0.05),术后24 h、48 h两组间的VAS评分比较,观察组低于对照组,差异有统计学意义(P<0.05),而术后2 h、6 h两组间的VAS评分比较,差异无统计学意义(P>0.05);术后24 h、48 h两组的血清β-内啡肽含量较本组术前均降低(P<0

  6. Epidural morphine for postoperative pain relief in children

    DEFF Research Database (Denmark)

    Henneberg, S W; Hole, P; Haas, Inge Madsen De

    1993-01-01

    Epidural morphine for postoperative pain relief is in general use, and has proved to be very efficient in adults. The epidural technique and the use of epidural morphine are much less frequent in children. For 2 years we have prospectively followed 76 children who had epidural morphine for postop......Epidural morphine for postoperative pain relief is in general use, and has proved to be very efficient in adults. The epidural technique and the use of epidural morphine are much less frequent in children. For 2 years we have prospectively followed 76 children who had epidural morphine...... for postoperative pain relief after major abdominal surgery. The age distribution was from newborn to 13 years, with a median age of 12 months. It was estimated that 94% of the patients had good analgesia for the first 24 postoperative hours and no other opioids were given. The side effects were few, but one case...... the investigation. We observed a change in the sleeping pattern with an increased number of sleep-induced myoclonia during the administration of epidural morphine. In conclusion, the use of epidural morphine in children for postoperative pain relief is very efficient. The minimal effective dose has not been...

  7. The influence of analgesia on labor--is it related to primary cesarean rates?

    Science.gov (United States)

    Wong, Cynthia A

    2012-10-01

    Multiple observational studies have reported an association between neuraxial (epidural, spinal, or combined spinal-epidural) labor analgesia and cesarean delivery. The purpose of this review is to summarize data from controlled trials addressing the question of whether neuraxial labor analgesia causes an increased risk of cesarean delivery. Additionally, the review will discuss whether the timing of initiation of analgesia or the specific type of neuraxial analgesia influences mode of delivery. Finally, the issue of external validity of published trials will be discussed. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. The effect of ropivacaine plus sufentanil on maternal and neonatal serum nitric oxide and cortisol in patient with controlled epidural analgesia during labor%0.1%罗哌卡因复合舒芬太尼用于无痛分娩对母婴一氧化氮及皮质醇的影响

    Institute of Scientific and Technical Information of China (English)

    杨世辉; 黄希照; 胡祖荣; 贾杰; 黎昆伟; 邓恋

    2012-01-01

    Objective To observe the analgesic efficacy and safety of ropivacaine ( 0. 1% ) plus sufentanil ( 0. 5 ug/mL ) for parturients with controlled epidural analgesia during labor. Methods One hundred healthy primiparas were randomized to two groups: PCEA group and control group. In the PCEA group, 15 mL loading dose and continuous background infusion by 5 mlVh of ropivacaine ( 0. 1% ) plus fentanyl ( 0. 05 μg/mL ), with controlled epidural analgesia were given to subjects. Maternal vital signs, visual analog scale ( VAS ) score, modified bromage scale ( MBS ) of motor block neonate and neonatal Apgar scores were recorded. Serum nitric oxide and cortisol of mothers and neonates were assessed. Results There was no significant difference in maternal demographic data, duration of labor, mode of delivery, Apgar score, and maternal vital signs between the two groups. VAS score was significantly higher in control group than that in PCEA group ( 7. 92 ± 1. 46 vs 0. 73 ± 0. 64, P 0.05).P组镇痛前后与C组相应时点VAS评分差异有统计学意义(P<0.05).分娩情况比较差异无统计学意义(P>0.05).两组均未观察到不良反应或椎管内麻醉的并发症.P组分娩后NO无明显变化,皮质醇浓度降低(P<0.05); C组NO下降(P<0.05),皮质醇浓度升高(P<0.05).结论 用0.1%罗哌卡因复合舒芬太尼PCEA用于无痛分娩,安全有效,降低皮质醇浓度,延缓母婴NO水平降低.

  9. [Combined epidural and spinal anesthesia for cesarean section].

    Science.gov (United States)

    Hody, J L

    1994-01-01

    Combined spinal epidural block has proven its efficacy in skilled hands. This technique allies advantages of spinal anaesthesia, regarding its speed of action and intensity of motor blockade and advantages of postoperative epidural analgesia. This block must be performed with great care and method to reach a success rate of almost 100%. Local anaesthetics and additives are reviewed and commented. The two main complications, hypotension and post dural puncture headache can be contained in very low limits.

  10. Comparação de morfina administrada por via intravenosa e via epidural com/sem bupivacaína ou ropivacaína no tratamento da dor pós-toracotomia com a técnica de analgesia controlada pelo paciente

    Directory of Open Access Journals (Sweden)

    Esra Mercanoğlu

    2013-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O objetivo deste estudo randomizado, duplo-cego e prospectivo foi determinar a eficácia e os efeitos colaterais da administração por via intravenosa ou epidural de morfina, bupivacaína ou ropivacaína no tratamento da dor pós-toracotomia. MÉTODOS: Sessenta pacientes submetidos a procedimentos de toracotomia eletiva foram randomicamente alocados em quatro grupos com o uso da técnica de envelopes lacrados. Os grupos MIV, ME, MEB e MER receberam morfina controlada pelo paciente por via intravenosa, e morfina, morfina-bupivacaína e morfina- ropivacaína epidural, respectivamente. Frequência cardíaca, pressão arterial e saturação de oxigênio perioperatórias e dor pós-operatória em repouso e durante a tosse, efeitos colaterais e necessidade de analgésicos de resgate foram registrados aos 30 e 60 minutos e em duas, quatro, seis, 12, 24, 36, 48 e 72 horas. RESULTADOS: A necessidade de sódio diclofenaco durante o estudo foi menor no grupo ME. A área sob a curva de tempo na VAS foi menor no grupo ME em comparação com o Grupo MIV, mas similar aos Grupos MEB e MER. Os escores de dor em repouso foram maiores nos tempos 12, 24, 36 e 48 horas no Grupo MIV em comparação com o Grupo ME. Os escores de dor em repouso foram maiores aos 30 e 60 minutos nos Grupos ME e MIV em comparação com o Grupo MEB. Os escores de dor durante a tosse aos 30 minutos foram maiores no grupo ME em comparação com o Grupo MEB. Não houve diferença entre os Grupos MIV e MER. CONCLUSÕES: Morfina administrada por via epidural foi mais eficaz do que por via intravenosa. A eficácia foi maior no grupo EM no período pós-operatório tardio e no Grupo MEB no período pós-operatório inicial. Concluímos que morfina administrada por via epidural foi a mais eficaz e preferida.

  11. Labor analgesia with ropivacaine added to clonidine: a randomized clinical trial

    National Research Council Canada - National Science Library

    Giane Nakamura; Eliana Marisa Ganem; Norma Sueli Pinheiro Módolo; Ligia Maria Suppo de Souza Rugolo; Yara Marcondes Machado Castiglia

    2008-01-01

    .... We examined the maternal-fetal effects of two pharmacological approaches: a low dose of ropivacaine or a lower dose of ropivacaine plus clonidine for epidural analgesia during labor. DESIGN AND SETTING...

  12. Epidural fentanyl decreases the minimum local analgesic concentration of epidural lidocaine

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jian; ZHENG Yue-ying; FENG Zhi-ying; CHEN Chao-qin; ZHU Sheng-mei

    2012-01-01

    Background Epidural lidocaine can be used when regional anesthesia needs to be established quickly,but the effect of co-administering epidural fentanyl on the minimum local analgesic concentration(MLAC)of lidocaine is not known.We compared the MLAC of epidural lidocaine in combination with different doses of fentanyl for epidural anesthesia in adults.Methods One hundred and twenty patients requiring epidural analgesia were randomly allocated to receive 20 ml of one of four solutions:lidocaine,or lidocaine plus fentanyl 1 μg/ml,2 μg/ml,or 3 μg/ml.The first patient in each group was administered 1% lidocaine weight by volume;subsequent patients received a concentration determined by the response of the previous patient to a higher or lower concentration according to up and down sequential allocation in 0.1% increments.Efficacy was assessed using a visual analog pain scale,and accepted if this was ≤10 mm on a 100 mm scale within 30 minutes.The extent of motor block and of nausea and vomiting were recorded at 30 minutes after administration of the epidural solution and two hours after surgery,respectively.Results The MLAC of lidocaine in those receiving lidocaine alone was 0.785%(95%C/0.738-0.864).A significant dose-dependent reduction was observed with the addition of fentanyl:the MLAC of lidocaine with fentanyl at 2 μg/ml was 0.596%(95%Cl 0.537-0.660)and 0.387% with fentanyl at 3 μg/ml(95%Cl 0.329-0.446,P<0.001).Conclusion Epidural fentanyl significantly reduces the dose of lidocaine required for effective epidural analgesia in adults without causing adverse side effects.

  13. Application of combined spinal-epidural anesthesia and analgesia in patients with hypertension during pregnancy%腰-硬联合阻滞镇痛在合并妊娠期高血压疾病产妇中的应用

    Institute of Scientific and Technical Information of China (English)

    于坚伟; 鲁花丽

    2016-01-01

    Objective To explore the safety and effectiveness of combined spinal-epidural anesthesia ( CSEA) and analgesia in the application of patients with hypertension during pregnancy. Methods 175 patients with pregnancy-induced hypertension syndrome and preeclampsia treated in grand hospital of Shanxian County from January 2012 to December 2015 were selected. Patients were divided into labor analgesia group (105 cases) and control group (70 cases) according to whether accepted combined spinal-epidural anesthesia and analgesia. Patients in the two groups were given the same blood pressure control and production process management, and patients in labor analgesia group were treated by combined spinal-epidural anesthesia for labor analgesia after 4 cm. Observational index including the women 's general situation, average arterial pressure in labor and birth process at each time point, delivery, maternal and infant complications and treatment situation. Results Compared to control group, patients in labor analgesia group had lower average arterial pressure at 60 min[(103. 7 ± 5. 7)mmHg vs (118. 2 ± 5. 5)mmHg], 120 min after active period[(104. 7 ± 4.3)mmHg vs (119.3 ±5.1)mmHg], the second stage of labor[(107.8 ±5.3)mmHg vs (114.8 ±6.1)mmHg], postpartum 120 min[(98.2 ±5.9)mmHg vs (103.8 ±6.7)mmHg] (P<0.05). The cesarean section rate of patients in labor analgesia group was 19. 0 %, lower than that in control group (34. 3 %) (P<0. 05). Compared to control group, patients in labor analgesia group had longer time of second stage of labor[(50. 3 ± 20. 5)min vs (42. 1 ± 19. 9)min] and higher rate of oxytocin use(60. 0 % vs 44. 3 %) (P<0. 05). Compared to control group, patients in labor analgesia group had lower rate of headache(6. 7 % vs 18. 6 %) and dizziness and antihypertensive therapy(12. 4% vs 38. 6%)(P<0. 05). Conclusion CSEA analgesia can reduce the cesarean section rate of patients with pregnancy-induced hypertension syndrome and preeclampsia, reduce puerperal

  14. [History and Technique of Epidural Anaesthesia].

    Science.gov (United States)

    Waurick, Katrin; Waurick, René

    2015-07-01

    In 1901, the first Epidural anesthesia via a caudal approach was independently described by two FrenchmanJean-Anthanase Sicard and Fernand Cathelin.. The Spanish military surgeon, Fidel Pagés Miravé, completed the lumbar approach successfully in 1921. The two possibilities for identification of the epidural space the "loss of resistance" technique and the technique of the "hanging drop" were developed by Achille Mario Dogliotti, an Italian, and Alberto Gutierrez, an Argentinean physician, at the same time. In 1956 John J. Bonica published the paramedian approach to the epidural space. As early as 1931 Eugene Aburel, a Romanian obstetrician, injected local anaesthetics via a silk catheter to perform lumbar obstetric Epidural analgesia. In 1949 the first successful continuous lumbar Epidural anaesthesia was reported by Manuel Martinez Curbelo, a Cuban. Epidural anaesthesia can be performed in sitting or lateral position in all segments of the spinal column via the median or paramedian approach. Different off-axis angles pose the challenge in learning the technique.

  15. Study on the Therapeutic Effect of 0.1% Levobupivacaine HCl on Ambulatory/Walking Epidural Analgesia in Labor%0.1%盐酸左旋布比卡因用于可行走镇痛分娩的疗效探讨

    Institute of Scientific and Technical Information of China (English)

    程娟; 王庆云; 王莲; 张亚娜

    2011-01-01

    Objective To investigate the therapeutic effect of0.1% levobupivacaine HCl on ambulatory or walking epidural analgesia in labor. Methods Based on the individual intention,200 hospitalized cases from February 2010 to March 2011 of full-term, singleton pregnancy,head delivery and primiparity,were divided into the observation group and the control group equally, which were then observed on stages of labor,changes of pain before and after analgesia, ways of delivery, use of oxytocin and the Apgar scores of newborns at one minute. Results The total stage of labor of observation groups was shorter than the control group, especially the active phase of the first stage, and the differences were statistically significant( P < 0.01 ); the pain after analgesia of experimental groups was less ,which was significantly contrast with pain before analgesia( P < 0.01 ) ;the difference of cesarean section rate between the two groups was significant( P < 0.05 );and the differences in use of oxytocin and newborns' Apgar scores at one minute were not statistically significant( P > 0.05 ). Conclusion 0.1% levobupivacaine HCl using in Epidural Analgesia is safe and effective for labor analgesia that it can shorten the stage of labor, reduce pain, lower the cesarean section rate, and has no effect on newborns.%目的 探讨0.1%盐酸左旋布比卡因硬膜外给药用于可行走镇痛分娩的临床效果.方法 根据个人意愿,将2010年2月至2011年3月在我院住院的足月妊娠、单胎、头位、初产200例分为实验组和对照组,每组各100例,实验两组产妇产程、镇痛前后疼痛变化、分娩方式、缩宫素使用情况及新生儿出生1分钟Apgar评分情况.结果 实验组总产程缩短,尤其是第一产程活跃期明显短于对照组,差异有统计学意义(P<0.01);实验组镇痛后疼痛程度明显减轻,与镇痛前比较差异有统计学意义(P<0.01);剖宫产率两组比较差异有统计学意义(P<0.05);实验组

  16. 不同浓度罗哌卡因在硬膜外镇痛分娩中应用效果比较%The clinical analysis of different concentrations of domestic ropivacaine of epidural analgesia in labor

    Institute of Scientific and Technical Information of China (English)

    朱鸣萍; 虞文青; 吴萍; 刘稚媛; 杨瑾

    2015-01-01

    目的 比较不同浓度罗哌卡因在硬膜外镇痛分娩中的应用效果及价值.方法 将300例住院分娩的产妇随机数字表法分为A、B、C三组,其中A组给予0.125%罗哌卡因复合苏芬太尼镇痛,B组给予0.1%罗哌卡因复合苏芬太尼镇痛,C组未要求镇痛分娩,观察三组分娩情况.结果 A组产程用时(261.38±19.87) min,产后2h出血量(241.03±34.57) rmL;B组产程用时(260.09±19.69) min,产后2h出血量(238.66±35.01) mL;C组产程用时(270.46±20.86)min,产后2h出血量(251.75±36.79) mL;组间差异均无统计学意义(t=0.472、1.035,均P>0.05).A组胎儿心率(142.34±21.57)次/min,新生儿Apgar评分(9.77±0.21)分,脐动脉血pH值(7.27±0.06);B组胎儿心率(145.21 ±21.49)次/min,新生儿Apgar评分(9.79±0.20)分,脐动脉血pH值(7.26±0.08);C组胎儿心率(143.78±22.01)次/min,新生儿Apgar评分(9.64±0.24)分,脐动脉血pH值(7.28±0.07);组问差异均无统计学意义(t=0.763、0.360、0.114,均P>0.05).A组镇痛起效时间(12.13±1.76) min,疼痛评分(1.03±0.46)分,镇痛后宫缩持续时间(22.39±3.21)s,镇痛后宫缩间隔时间(3.26±1.49) min,剖宫产率为8.00%;B组镇痛起效时间(12.04±1.69) min,疼痛评分(1.01±0.52)分,镇痛后宫缩持续时间(21.04±3.18)s,镇痛后宫缩间隔时间(3.49±1.51) min,剖宫产率为9.00%;C组镇痛起效时间(16.77 ±2.51) min,疼痛评分(3.76±1.23)分,镇痛后宫缩持续时间(26.98 ±5.87)s,镇痛后宫缩间隔时间(2.65±0.75) min,剖宫产率为48.00%;组间差异均有统计学意义(x2或t =6.148、8.522、5.749、4.095、61.316,均P<0.05).结论 采用0.1%罗哌卡因复合苏芬太尼进行分娩镇痛即能够有效减轻患者疼痛、缩短产程并减少产后2h出血量,同时对宫缩影响小,降低剖宫产率,对新生儿无影响,值得在临床上推广应用.%Objective To compare the effect of different concentrations of ropivacaine in epidural analgesia of childbirth

  17. [Horner syndrome following combined spinal-epidural anesthesia].

    Science.gov (United States)

    Karaca, Ömer; Kumaş Solak, Sezen; Demirgan, Serdar; Bademci, Mehmet

    2016-07-01

    Horner syndrome is rarely observed in connection with epidural anesthesia. It is characterized by ptosis, enophthalmos, miosis, anisocoria, and conjunctival hyperemia in the affected eye, as well as anhydrosis and flushing on the affected side of the face. It is usually a complication spontaneously resolved without permanent neurological deficits. Intraoral anesthesia; stellate ganglion, cervical or brachial plexus blocks; thoracic, lumbar or caudal epidural anesthesia, and intrapleural analgesia are the main causes for Horner syndrome related to anesthesia. Among other causes of Horner syndrome are head and neck surgery, trauma, and puncture of internal jugular vein. The present case of unilateral Horner syndrome appeared in the aortobifemoral bypass after lumbar spinal- epidural anesthesia.

  18. Ketamina epidural en cirugía de hemiabdomen inferior Epidural ketamine in low abdominal surgery

    Directory of Open Access Journals (Sweden)

    S. F. González-Pérez

    2006-04-01

    Full Text Available Introducción: La ketamina de uso corriente es una droga utilizada principalmente para la inducción y el mantenimiento de la anestesia, compuesta por una mezcla racémica de enantiómeros R (- y S (+. En la década de los años 80 comienza la administración humana de la ketamina por vía epidural. A partir de entonces se han presentado disímiles investigaciones para justificar su acción analgésica en este espacio con varias hipótesis: 1 supresión específica laminar de las astas dorsales, 2 mediación por el sistema opioide endógeno y sustancia gris periacueductal, y 3 bloqueo de los canales del calcio por antagonismo no competitivo de los receptores N-metil-d-aspartato. Objetivo: Demostrar la eficacia de la ketamina por vía epidural como analgésico postoperatorio en la cirugía de hemiabdomen inferior. Material y Método: Se realizó un ensayo clínico aleatorizado y prospectivo en una muestra de 50 pacientes operados de hernia inguinal electiva. Los pacientes fueron divididos en dos grupos, un grupo tratado con 50 mg de ketamina y otro grupo al que se le administró una dosis de 2 mg de morfina liofilizada. Resultados: la ketamina por vía epidural en una dosis de 50 mg proporciona una analgesia adecuada por un período de al menos de 6 horas. La morfina brinda una analgesia por encima de las 18 horas. Conclusión: La ketamina por vía epidural es menos efectiva que la morfina desde el punto de vista analgésico, pero es una alternativa importante pues permite disminuir la dosis de morfina si se combinan ambos fármacos o se asocia a anestésicos locales.Introduction: Ketamine is a drug used for induction and maintenance of anesthesia, exists as a racemic mixture of R- and S+-enantiomers. Epidural ketamine starts to human administration about 80’ years. After that, various studies have been published about the mechanism of analgesic action of ketamine: lamina-specific suppression of dorsal-horn unit activity (1, opiate agonist at

  19. Controlled release ibuprofen-poloxamer gel for epidural use - A pharmacokinetic study using microdialysis in pigs.

    Science.gov (United States)

    Paavola, Anne; Bernards, Christopher M; Rosenberg, Per H

    2016-11-01

    In order to avoid the risks of sideeffects of epidural local anesthetics and opioids, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) epidurally would be an interesting option of analgesic therapy. The fairly short duration of action of spinally administered NSAIDs, e.g., ibuprofen, may be prolonged by using controlled release poloxamer gel formulation. Using a microdialysis technique we studied the epidural and intrathecal pharmacokinetics of ibuprofen after its epidural administration as a poloxamer 407 formulation or a solution formulation. In addition, plasma ibuprofen concentrations were analyzed from central venous blood samples. Ibuprofen concentrations in the epidural space were significantly higher and longer lasting after the epidural gel injection compared with the epidural solution injection. The epidural AUC of ibuprofen was over threefold greater after epidural ibuprofen gel injection compared with the ibuprofen solution injection (pgel was very low. The in situ forming poloxamer gel acted as a reservoir allowing targeted ibuprofen release at the epidural injection site and restricted ibuprofen molecules to a smaller spinal area. Ibuprofen diffusion from the epidural space to the intrathecal space was steady and prolonged. These results demonstrate that the use of epidurally injectable poloxamer gel can increase and prolong ibuprofen delivery from epidural space to the CSF enhancing thus ibuprofen entry into the central neuroaxis for spinal analgesia. Further toxicological and dose-finding studies are justified.

  20. A “ COMPARATIVE STUDY BETWEEN BUPIVACAINE 0.5% AND ROPIVACAINE 0.75% IN EPIDURAL ANALGESIA IN PATIENTS U NDERGOING ELECTIVE LOWER ABDOMINAL AND LOWER LIMB SURGERIES ”

    Directory of Open Access Journals (Sweden)

    Sachidanand

    2015-09-01

    Full Text Available BACKGROUND : Regional anaesthesia is noted for its simplic ity, safety and effectiveness. Though spinal anaesthesia provides an efficient block it has some limitations. Epidural anaesthesia is one of regional techniques for lower abdominal and lower limb surgeries. Bupivacaine is the drug of choice for providing e ffective epidural analgesia. Ropivacaine is new long acting local anaesthetic with similar chemical structure but with less cardio toxicity and CNS toxicity. We did a Prospective Randomised control study to c o m p a r e between t wo g r o u ps - 20 m l o f 0.75% R op i v ac a i ne ( I sob ar i c a nd 20 m l 0. 5 % B up i v a ca i ne ( I sob ar i c f o r e p i du ra l a n ae s t h e s i a i n l ow e r a bdo mi n a l a nd l ow e r li m b su r g er i e s i n a du lt s a g e d 1 8 t o 60 y e ar s. AIM : To compare in two groups - 20 m l o f 0.75% R op i v aca i ne ( I sob ar i c a nd 20 m l 0. 5 % B up i v a ca i ne ( i sob ar i c f o r e p i du ra l a n ae s t h e s i a i n l ow e r a bdo mi n a l a nd l ow e r li m b su r g er i e s i n a du lt s DESIGN : A Prospective randomized control study . METHODS : Th e s t ud y p o p ul a t i on w as r a nd o m l y di v id e d in t o 2 g r o up s w i t h 30 p a t i e n t s i n e a c h g r o up . S t ud y g r o u p R - rece i v e d 20 m l of 0.75% Ro pi v a c a in e ( I so b a r i c b y e pidu r al r o u t e S t ud y g r o u p B - rece i v e d 20 m l of 0.5% B upi v a c a in e ( i so b a r i c b y e pidu r al r o u t e and compared 1. Ons e t of s e nso r y a nd m o t or b l o c k, 2. H i g h e st l e v e l of s e nso r y b l o c k, 3. D e g r e e of m o t or b l o c k a d e ( U s i ng Mod i f i e d B r o m a g e s c a l e 4. Du ra ti on of m o t or b l o c k a de. 5. Du ra ti on of s e nso r y a n a l g e s i a. 6. Haemodynamic changes heart rate, blood pressure, respiratory rate. 7. S ide effects if any . R ESULTS : 0.75% R op i v aca i ne h a s a sho r t e r du ra ti on of m o t o r b l o c k

  1. Quebra de cateter no espaço peridural Rotura de catéter en el espacio epidural Breakage of a catheter in the epidural space

    Directory of Open Access Journals (Sweden)

    Cristian Sbardelotto

    2008-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A quebra do cateter peridural durante sua remoção é rara, porém descrita. O conhecimento das possíveis complicações e o manuseio adequado são responsabilidades do anestesiologista. O objetivo deste relato foi apresentar caso de quebra de cateter peridural em analgesia de parto. RELATO DO CASO: Paciente do sexo feminino, 33 anos, GII, PI, deu entrada na maternidade em trabalho de parto. Após duas horas de evolução, a paciente solicitou analgesia. Ao exame, encontrava-se em fase ativa do trabalho de parto, com dilatação cervical de 5 cm, dinâmica uterina regular, bolsa rota, com dor classificada pela Escala Visual Analógica - VAS 10. Iniciada a analgesia de parto pela técnica combinada com dupla punção. Durante a evolução foi feita uma complementação analgésica pelo cateter. Na retirada houve pequena dificuldade e conseqüente rompimento do mesmo. Optou-se pela realização de uma tomografia axial computadorizada e radiografia da região lombar que não mostrou evidência do fragmento do cateter. Visto que a paciente evoluiu assintomática clinicamente, sem sinais de irritação radicular, dor ou infecção, procedeu-se às devidas orientações e alta hospitalar. CONCLUSÕES: Cateteres peridurais em região lombar são, em ocasiões raras, difíceis de remover. Fatores que podem aumentar as chances de formação de nós e risco de quebra do cateter foram relacionados. Neste caso, um dos principais fatores envolvidos foi a introdução excessiva do cateter peridural lombar. Felizmente, as complicações neurológicas são ainda mais raras, e seguindo as diretrizes de uma tração lenta e suave na ausência de parestesias, na maioria das vezes, o cateter é removido com sucesso.JUSTIFICATIVA Y OBJETIVOS: La rotura del catéter epidural durante su retirada es rara, pero ya se ha descrito. El conocimiento de las posibles complicaciones y el manejo adecuado es de total responsabilidad del anestesi

  2. An analysis on the effects of different time of stopping pumping on stages of labour and delivery outcomes during self-controlled combined spinal-epidural labour analgesia%自控腰硬联合分娩镇痛不同的停泵时机对产程和分娩结局的影响

    Institute of Scientific and Technical Information of China (English)

    熊桂生; 潘丽莉; 王玉珏

    2014-01-01

    目的:探讨自控腰硬联合分娩镇痛麻醉下,初产妇分娩过程中不同的停泵时机对产程、分娩结局和产妇满意度的影响。方法选择2013年4月~2013年12月间符合条件的初产妇120例,按先后顺序分到A、B、C三组,每完成10个另起一组,每组40例,腰硬联合麻醉分娩镇痛,A组宫口开全停泵,不再开泵;B组宫口开全停泵,胎儿娩出后立即开泵;C组一、二、三产程持续镇痛,三组均于第三产程结束,会阴缝合术毕结束镇痛并拔硬外镇痛管。观察比较产妇基本情况、镇痛效果(VAS)评分、第1、2、3产程时间、产后2h内出血量、缩宫素使用、剖宫产率、钳产率、羊水性质、产妇满意度,新生儿Apgar评分。结果三组间产后2h出血、新生儿Apgar评分、第三产程时间差异无统计学意义;A、B组产妇分娩痛比例较C组增加,会阴缝合痛或不适者较C组多,C组产妇满意度较A、B组增加,差异有统计学意义,A、B组间各项指标间差异无统计学意义。结论不同的停泵时机不增加第二产程,不影响新生儿Aparg评分,不增加产后出血,持续用药组增加缩宫素使用率,差异有统计学意义(P<0.05),可能增加剖宫产趋势,但可提高产妇满意度。%Objective To explore the effects of different time of stopping pumping on stages of labour, delivery outcomes and parturients' satisfaction during delivery of primiparas who received self-controlled combined spinal-epidural anaesthesia for labour analgesia. Methods 120 eligible primiparas who were admitted from April 2013 to December 2013 were selected and assigned to group A, B and C according to admission order. Every ten people were assigned to each group once a time. Each group had 40 primiparas and received combined spinal-epidural labour analgesia. Pumping was stopped when cervix was wide open for group A and never restarted; pumping was stopped when

  3. Combined Spinal Epidural versus Epidural Sufentanil and Bupivacaine in Labour (Clinical and Histological comparative Study

    Directory of Open Access Journals (Sweden)

    Nagia M. Abd El Moeti, *Zinab B. Youssef, *Soaad S. Abd El Aal

    2006-12-01

    Full Text Available Introduction:- Regional analgesia provides excellent pain relif in labour. This study was designed to compare combined spinal eqidural (CSE versus epidural block using a narcotic (sufentanil and local anaesthetic bupivacaine regarding their effects on progress of labour, method of delivery, pain relif, side effects and neonatal outcome. Patients and Methods :-Forty pregnant women ASA I and II were enrolled in this study. The women were randomly allocated to receive either CSE or epidural ( 20 patient of each . In CSE group analgesia was initiated with 10ug sufentanil with 2mg bupivacaine. In epidural group 10ml bupivacaine 0.125%.and 10ug sufentanil injected epidurally. In both groups the continuous infusion of 0.83% bupivacaine with 0.33ug/ml sufentanil at 10ml/hr adjusted as required. Maternal haemodynamics, analgesia characteristics VAPS, degree of motor block, were measured. Duration of labour, cervical dilation, maternal satisfaction and mode of delivery were assessed. Foetal outcome was assessed by 1 and 5 min. Apgar score and umbilical venous blood gases. Maternal and neonatal side effects were observed. The experimental study was done on 30 rats divided into 3 groups 10 rats of each. Control group (A injected intrathecally with saline, group (B injected intrathecally with 1.5ug/kg sufentanil (low dose, and group (C injected intrathecally with 7.5ug/kg sufentanil (high dose, the pervious doses were injected every 2hr. for 3 times then the spinal cord was obtained and stained for histological evaluation. Results:- The clinical study showed that no difference between the 2 groups for the degree of motor block or adequacy of analgesia, mode of delivery and Foetal outcome. The onset of analgesia was faster with CSE technique, more patient satisfaction and more pruritis. The histological results revealed that no detectable significant neurotoxic changes with the use of small dose of intrathecal sufentanil but mild changes occurred with high

  4. 硬膜外注射右美托咪定、芬太尼用于下肢手术镇痛的效果评价%Evaluation of the effects of dexmedetomidine and fentanyl for epidural analgesia in lower limb surgeries

    Institute of Scientific and Technical Information of China (English)

    汪涛; 王志春; 朱安祥; 张奎; 陈树秀; 周巧林

    2015-01-01

    目的 观察和评价硬膜外注射右美托咪定、芬太尼复合罗哌卡因用于下肢手术的镇痛效果.方法 美国麻醉医师协会(ASA)分级Ⅰ~Ⅱ级患者100例,按随机数字表法分为两组(每组50例):罗哌卡因+右美托咪定组(RD组)和罗哌卡因+芬太尼组(RF组).除记录循环、呼吸指标及镇静评级外,于硬膜外给药后即刻观察T1o痛觉消失时间、最高感觉阻滞平面、完全运动阻滞时间、感觉阻滞消退两个节段的时间、首次追加镇痛药物的时间及副作用的发生情况等.结果 两组患者一般情况差异无统计学意义(P>0.05).RD组T10痛觉消失和完全运动阻滞时间[(7.1±1.2)min和(18.0±3.6) min]明显早于RF组[(9.2±1.8) min和(22.0±3.0) min](P<0.05),RD组术后镇痛时间[(361±20) min]长于RF组[(259±32) min],且硬膜外局麻药总用量[(76±10)mg]显著少于后者[(97±l4)mg](P<0.01);镇静效果评级RD组(76%)显著好于RF组(18%)(P<0.01).RF组恶心、呕吐的发生率(28%和14%)较RD组(16%和6%)明显升高(P<0.05),而RD组口干的发生率(16%)显著高于RF组(4%)(P<0.01).结论 硬膜外注射右美托咪定用于下肢手术镇痛,可提供较为稳定的血流动力学,感觉神经阻滞起效快,术后镇痛时间延长,药物用量少,镇静效果良好.%Objective To observe and evaluate the analgesia potentiating effects of epidurally administered fentanyl and dexmedetomidine when combined with ropivacaine.Methods One hundred ASA Ⅰ-Ⅱ patients undergoing lower limb orthopedic surgery were randomly divided into two groups (n=50):ropivacaine+dexmedetomidine group (RD group) and ropivacaine+fentanyl group (RF group).Besides cardio-respiratory parameters and sedation scores,various block characteristics were also observed including the onset of T10 analgesia time,maximum sensory analgesic time,complete motor blockade time,two segmental dermatomal regressions time,first rescue analgesic time,and the

  5. Comparison of the antalgic effects of epidural and intravenous patient-controlled analgesia with fentanyl after cesarean section%芬太尼静脉和硬膜外自控镇痛在剖宫产术后的对比观察

    Institute of Scientific and Technical Information of China (English)

    冯雪容; 李淑; 邹振宇

    2011-01-01

    Objective To compare the effects of patient-controlled intravenous analgesia( PCIA) with patient-controlled epidural analgesia (PCEA) with fentanyl after cesarean section.Methods 60 patients undergoing cesarean section were randomly assigned into two groups: group PCIA and group PCEA, 30 cases for each group.The analgesic solution for PCIA was fentanyl (20ug/kg) plus tropisetron (5mg), and that for PCEA was fentanyl (5ug/kg) plus 1.192% ropivacaine.The analgesia and sedation efficacy was assessed by visual analogue scale ( VAS) and Ramsay sedation score (RSS).The plasma prolaction concentrations, the recovery of bowel movement, the adverse effects during analgesia period were observed.Results The efficacy of analgesia in group PCEA was better than that in group PCIA.The RSS score was significantly higher in group PCIA than that in group PCEA.No significant difference was found in the overall satisfaction on analgesia therapy.The incidence of dizziness in group PCIA was higher than that in group PCEA.There was no significant difference between two groups in the recovery of bowel movement, the plasma level of prolactin, nausea,vomiting, pruritus and respiration frequency.Conclusions PCIA with PCEA could provide similar analgesia efficacy using fentanyl in patients undergoing cesarean section.Both PCIA and PCEA have less adverse effects.%目的 观察剖宫产术后芬太尼静脉自控镇痛(PCIA)和硬膜外自控镇痛(PCEA)的镇痛效果.方法 60例剖宫产手术患者随机分为PCLA组和PCEA组,每组30例.PCLA组术毕应用芬太尼20μg/kg、托烷司琼5 mg静脉镇痛;PCEA组术毕应用芬太尼5 μg/kg、1.192%甲磺酸罗哌卡因20ml硬膜外镇痛.采用视觉模拟评分(visual analogue scale,VAS)和Ramsay镇静评分(Ramsay sedation score,RSS)观察两组患者术后的镇痛、镇静效果.并观察术后血浆泌乳素浓度、肠蠕动恢复时间和镇痛期间可能出现的不良反应.结果 PCEA组镇痛效果优于PCIA组,PCIA组RSS

  6. A COMPARATIVE STUDY OF EPIDURAL BUTORPHANOL AND EPIDURAL FENTANYL FOR THE RELIEF OF POST-OPERATIVE PAIN IN LOWER ABDOMINAL AND LOWER LIMB SURGERIES

    Directory of Open Access Journals (Sweden)

    Ashwini

    2014-11-01

    Full Text Available BACKGROUND: Epidural anaesthesia is used extensively for both intra-operative and post-operative analgesia. This prospective randomized study was conducted using opioids epidurally for post-operative analgesia. Fentanyl is a pure opioid agonist. Butorphanol tartarate which is an agonist antagonist opioid is considered safer than pure opioid agonist. Hence, we compared epidural 4mg butorphanol and epidural 100 µg fentanyl for the relief of post-operative pain. AIMS AND OBJECTIVES: To compare the onset, duration, quality of analgesia, hemodynamic effects and side effects between the 2 study drugs. MATERIALS AND METHODS: 60 patients of either sex posted for elective lower abdominal and lower limb surgeries were randomly divided into 2 groups of 30 each. Group A received butorphanol 4mg epidurally. Group B received fentanyl 100 µg epidurally. All surgeries were done under lumbar epidural anaesthesia with catheter in situ. Post-operatively when patients complained of pain, intensity of pain was assessed using visual analogue scale [VAS]. When the VAS score was > 5, Group A received butorphanol 4mg diluted to 10 ml with NS or Group B received 100 µg fentanyl epidurally diluted to 10 ml with NS. Onset, duration, quality of analgesia, hemodynamic effects and incidence of side effects were compared between the two groups and treated accordingly. RESULTS: Demographic profile was comparable in both groups. Mean time of onset of analgesia was rapid (3.22 ±0.9 (S.D min in group B compared to group A (6.38± 1.26 (S.D min. Duration of analgesia was longer in group A (344.00 ±63.39 min compared to group B (227±38.12 min. Quality of analgesia was better with group A compared to group B. There was no significant difference in hemodynamic parameters in both groups. Sedation was the main side effect in group A. Incidence of pruritis, vomiting, hypotension and respiratory depression was more in group B. CONCLUSION: Epidural Butorphanol though has a delayed

  7. Occult Spinal Dysraphism in Obstetrics: A Case Report of Caesarean Section with Subarachnoid Anaesthesia after Remifentanil Intravenous Analgesia for Labour

    Science.gov (United States)

    Valente, A.; Frassanito, L.; Natale, L.; Draisci, G.

    2012-01-01

    Neuraxial techniques of anaesthesia and analgesia are the current choice in obstetrics for efficacy and general low risk of major complications. Concern exists about neuraxial anaesthesia in patients with occult neural tube defects, regarding both labour analgesia and anaesthesia for Caesarean section. Recently, remifentanil infusion has been proposed as an analgesic technique alternative to lumbar epidural, especially when epidural analgesia appears to be contraindicated. Here, we discuss the case of a pregnant woman attending at our institution with occult, symptomatic spinal dysraphism who requested labour analgesia. She was selected for remifentanil intravenous infusion for labour pain and then underwent urgent operative delivery with spinal anaesthesia with no complications. PMID:22844625

  8. Occult Spinal Dysraphism in Obstetrics: A Case Report of Caesarean Section with Subarachnoid Anaesthesia after Remifentanil Intravenous Analgesia for Labour

    Directory of Open Access Journals (Sweden)

    A. Valente

    2012-01-01

    Full Text Available Neuraxial techniques of anaesthesia and analgesia are the current choice in obstetrics for efficacy and general low risk of major complications. Concern exists about neuraxial anaesthesia in patients with occult neural tube defects, regarding both labour analgesia and anaesthesia for Caesarean section. Recently, remifentanil infusion has been proposed as an analgesic technique alternative to lumbar epidural, especially when epidural analgesia appears to be contraindicated. Here, we discuss the case of a pregnant woman attending at our institution with occult, symptomatic spinal dysraphism who requested labour analgesia. She was selected for remifentanil intravenous infusion for labour pain and then underwent urgent operative delivery with spinal anaesthesia with no complications.

  9. Post-operative analgesic effect of epidural bupivacaine alone and ...

    African Journals Online (AJOL)

    unpleasant sensory associated with actual or potential tissue damage (Muir. III, 2009). Ongoing ... including reduction of food and water consumption, normal respiration ... procedure in veterinary practice (Breivik, 2003). Tramadol is ..... Principles of sedation, analgesia and ... Evaluation of the analgesic effects of epidurally.

  10. Analgesia e sedação da associação da clonidina e ropivacaína a 0,75% por via peridural no pós-operatório de colecistectomia aberta Analgesia y sedación de la asociación de la clonidina y ropivacaína a 0,75% por vía peridural en el pos-operatorio de colecistectomia abierta Analgesia and sedation with epidural clonidine associated to 0.75% ropivacaine in the postoperative period of open cholecystectomy

    Directory of Open Access Journals (Sweden)

    Antonio Mauro Vieira

    2003-09-01

    edades variando de 18 a 50 años, con peso entre 50 y 100 kg, estado físico ASA I y II, sometidos a colecistectomia, y que fueron distribuidos en dos grupos: Control (GC, en que fue administrada ropivacaína a 0,75% (20 ml, asociada al clorato de sodio a 0,9% (1 ml; Experimento (GE, en que fue inyectada ropivacaína a 0,75% (20 ml, asociada a la clonidina (1 ml = 150 µg. La analgesia y la sedación fueron observadas 2, 6 y 24 horas después del término del momento operatorio. RESULTADOS: La media de edad en el GC fue de 41 años y de 37 años en el GE. La media de peso fue de 67 kg en el GC y de 64 kg en el GE. La sedación en el pos-operatorio fue significativamente mayor en los pacientes a las 2 y 6 horas del grupo de experimento. La analgesia fue observada en mayor número de pacientes del grupo de experimento, cuando comparada al grupo control. CONCLUSIONES: La asociación de clonidina y ropivacaína produjo analgesia que dura más, y sedación en pacientes, en los horarios de observación de 2 y 6 horas.BACKGROUND AND OBJECTIVES: Epidural clonidine has analgesic properties and potentiates local anesthetic effects; there are, however, some side effects including: arterial hypotension, bradycardia and sedation. This study aimed at evaluating analgesia and sedation of clonidine associated to 0.75% ropivacaine in the postoperative period of open cholecystectomy. METHODS: Participated in this study 30 patients of both genders, aged 18 to 50 years, weighing 50 to 100 kg, physical status ASA I or II, submitted to cholecystectomy, who were distributed in two groups: Control Group (CG received 0.75% ropivacaine (20 ml with saline solution (1 ml; Experimental Group (EG received 0.75% ropivacaine (20 ml with clonidine (1 ml = 150 µg. Analgesia and sedation were observed at 2, 6 and 24 postoperative hours. RESULTS: Mean age was 41 yr in CG and 37 yr in EG. Mean weight was 67 kg in CG and 64 kg to EG. Postoperative sedation was significantly higher at 2 and 6 hours in the

  11. Administración epidural de lidocaína, morfina y detomidina para la resección quirúrgica de un tumor de pene en un toro joven (Epidural administration of lidocaine, morphine and detomidine for surgical removal of a tumour in a young bull penis

    Directory of Open Access Journals (Sweden)

    Castiñeiras Pérez, Eva:

    2007-04-01

    Full Text Available ResumenCon objeto de mejorar la fertilidad en las explotaciones, algunos ganaderos optan por la presencia de un toro para la monta natural. En toros jóvenes es relativamente común la aparición de fibropapilomas en el pene. Esta patología está causada por un adenovirus quepenetra a través de pequeñas heridas, dando lugar a neoplasias en la porción libre del pene. Por lo general, suelen ser de naturaleza benigna y sólo se recomienda su eliminación quirúrgica cuando dificultan la monta.1 Aunque, en los animales de producciónnunca se ha tenido muy en cuenta la analgesia intra y postoperatoria, estudios recientes muestran que el control del dolor permite una más rápida y mejor recuperación. La anestesia epidural se ha convertidoen una técnica muy utilizada para el control del dolor en diversas especies domésticas. La administración epidural de lidocaína 2% (0,2 mg/kg, morfina 2% (0,3 mg/kg y detomidina 1% (30 µg/kg en un volumen total de 14 ml, proporciona en el ganado vacuno unabuena anestesia y analgesia en ambas fosas paralumbares, abdomen,extremidades posteriores, ubre, ano, periné, vulva y vagina durante más de 100 minutos. El animal permanece de pie con mínimos efectoscardiorrespiratorios.2 La aplicación epidural antes descrita permite la exploración del aparato reproductor del animal y proporcionaanestesia y analgesia para la eliminación del tumor en el pene. Al permanecer de pie, se evitan toda una serie de problemas asociados al decúbito en el bovino (timpanismo, daños musculares y nervioso, etc..

  12. 连续硬膜外自控镇痛对剖宫产术后产妇恢复及血清泌乳素的影响%Effect of patient controlled epidural analgesia on recovery and serum prolactin of parturient after undergoing cesarean section

    Institute of Scientific and Technical Information of China (English)

    唐萍

    2011-01-01

    Objective To discuss the effect of patient controlled epidural analgesia on recovery and serum prolactin of parturient after undergoing cesarean section.Methods Eighty-six cases with cesarean section patients were classified into two groups by random digits table,which observation group with 43 cases were used patient controlled epidural analgesia,and control group with 43 cases were used intramuscular pethidine.The analgesic effect and serum prolactin between the two groups were compared.Results The good rate in observation group was 79.1%(34/43 ),significantly higher than that in control group [20.9%( 9/43 ) ](P < 0.05 ).Compared with pre-operation,the level of prolactin in observation group was significantly increased [ ( 542.17 ± 46.75 ) μ g/L vs.( 351.13 ± 20.92 ) μ g/L] ( P < 0.05 ).Moreover,the level of prolactin in observation group after operation was significantly higher than that in control group [ (362.12 ± 24.33)μ g/L ] ( P < 0.05 ).The colostrum time in observation group was ( 15.21 ± 3.26 ) h which was shorter than that in control group [ (21.16 ± 4.78) h ] (P < 0.05).Conclusion The analgesic effect of patient controlled epidural analgesia on parturient after undergoing cesarean section is good,which can help patients recovery and improve the level of serum prolactin,which can be applied in clinic.%目的 探讨连续硬膜外自控镇痛对剖官产术后产妇恢复及血清泌乳素的影响.方法将86例行剖宫产术产妇按随机数字表法分为两组,观察组43例采用连续硬膜外自控镇痛,对照组43例采用哌替啶肌肉注射,比较两组的镇痛效果及血清泌乳素水平变化.结果观察组镇痛优良率[79.1% (34/43)]明显高于对照组[20.9% (9/43)](P<0.05).观察组术后泌乳素水平[(542.17±46.75)μg/L]较术前[(351.13±20.92)μg/L]明显升高(P<0.05),且明显高于对照组术后[(362.12±24.33)μ g/L](P< 0.05).观察组的初乳时间[(15.21±3.26)h

  13. Effect of Epidural Labor Analgesia on Placental Secretion of Cortisol and Prostaglandin E2%硬膜外分娩镇痛对胎盘组织中皮质醇、前列腺素E2水平的影响

    Institute of Scientific and Technical Information of China (English)

    徐家丽; 冯丹

    2013-01-01

    目的 研究硬膜外分娩镇痛对分娩时胎盘组织中皮质醇(Cortisol)、前列腺素E2(PGE2)等的影响.方法 40例单胎初产妇随机均分成两组,即对照组(未施任何镇痛措施)和镇痛组(行硬膜外分娩镇痛).两组产妇分别在"宫口开3 cm、宫口开3 cm后1 h、胎儿娩出时"各抽取肘静脉血10 mL,胎儿娩出后抽取脐血和羊水各10 mL,用ELISA分析法测量血、羊水中Cortisol、PGE2的浓度,以研究硬膜外分娩镇痛对胎盘分泌Cortisol、PGE2的影响.同时监测第一、二产程时间、分娩方式以及VAS镇痛评分等.结果 与对照组相比,行硬膜外分娩镇痛后镇痛组产妇VAS镇痛评分明显下降,差异有统计学意义(P0.05);两组外周血、脐血以及羊水中PGE2的水平差异无统计学意义(P>0.05);两组产妇第一、二产程时间、分娩方式等指标差异无统计学意义.结论 分娩镇痛明显减轻了产妇的疼痛应激反应,降低产妇外周血中Cortisol的水平,但不影响胎盘组织中Cortisol、PGE2的水平,对产程、分娩方式无明显影响,是一项安全有效的镇痛方法.%Objective To investigate the effect of epidural labor analgesia on placental secretion of cortisol and prostaglan -din E2 (PGE2). Methods Forty full-term primiparous parturients who were at ASA physical status Ⅰ or Ⅱ were randomly divided into two groups in terms of the application of epidural analgesia or not:control group and analgesia group (n= 20 each ). A 10 mL blood sample was drawn from the elbow venous of each parturient at the time of "3 cm cervical dilation" ,"one hour after 3-cm cervical dilation" and "fetal disengagement". A 10 mL umbilical cord blood sample and a 10 mL sample of amniotic fluid were collected separately after delivery. The ELISA method was used to measure the concentration of cortisol and PGE2 in the collected samples. Time frame for the first and the second stage of labor, VAS scores and mode of delivery were measured

  14. The effect of 0.5% ropivacaine on epidural blood flow

    DEFF Research Database (Denmark)

    Dahl, J B; Simonsen, L; Mogensen, T;

    1990-01-01

    Twenty patients scheduled for elective abdominal surgery received epidural analgesia with 20 ml 0.5% ropivacaine or 0.5% bupivacaine. Epidural blood flow was measured by an epidural 133Xe clearance technique on the day before surgery (no local anaesthetic) and again 1 h before surgery, 30 min after...... injection of the local anaesthetic during continuous infusion (8 ml/h). Median initial blood flow was 5.0 ml/min and 6.0 ml/min per 100 g tissue in patients receiving ropivacaine and bupivacaine, respectively. After epidural bupivacaine, blood flow increased in 8 of 10 patients to 6.9 ml/min per 100 g...

  15. Preventive analgesia

    DEFF Research Database (Denmark)

    Dahl, Jørgen B; Kehlet, Henrik

    2011-01-01

    findings: The nature of central sensitization during acute and chronic postsurgical pain share common features, and there may be interactions between acute and persistent postoperative pain. The term ‘pre-emptive analgesia’ should be abandoned and replaced by the term ‘preventive analgesia’. Recent studies......This paper will discuss the concepts of pre-emptive and preventive analgesia in acute and persistent postsurgical pain, based on the most recent experimental and clinical literature, with a special focus on injury-induced central sensitization and the development from acute to chronic pain. Recent...... of preventive analgesia for persistent postoperative pain are promising. However, clinicians must be aware of the demands for improved design of their clinical studies in order to get more conclusive answers regarding the different avenues for intervention. Summary: The concept of preventive analgesia is still...

  16. Epidural catheterization in cardiac surgery: The 2012 risk assessment

    Directory of Open Access Journals (Sweden)

    Thomas M Hemmerling

    2013-01-01

    Full Text Available Aims and Objectives: The risk assessment of epidural hematoma due to catheter placement in patients undergoing cardiac surgery is essential since its benefits have to be weighed against risks, such as the risk of paraplegia. We determined the risk of the catheter-related epidural hematoma in cardiac surgery based on the cases reported in the literature up to September 2012. Materials and Methods: We included all reported cases of epidural catheter placement for cardiac surgery in web and in literature from 1966 to September 2012. Risks of other medical and non-medical activities were retrieved from recent reviews or national statistical reports. Results: Based on our analysis the risk of catheter-related epidural hematoma is 1 in 5493 with a 95% confidence interval (CI of 1/970-1/31114. The risk of catheter-related epidural hematoma in cardiac surgery is similar to the risk in the general surgery population at 1 in 6,628 (95% CI 1/1,170-1/37,552. Conclusions: The present risk calculation does not justify not offering epidural analgesia as part of a multimodal analgesia protocol in cardiac surgery.

  17. A randomised controlled trial using the Epidrum for labour epidurals.

    LENUS (Irish Health Repository)

    Deighan, M

    2015-03-01

    The aim of our study was to determine if using the Epidrum to site epidurals improves success and reduces morbidity. Three hundred parturients requesting epidural analgesia for labour were enrolled. 150 subjects had their epidural sited using Epidrum and 150 using standard technique. We recorded subject demographics, operator experience, number of attempts, Accidental Dural Puncture rate, rate of failure to site epidural catheter, rate of failure of analgesia, Post Dural Puncture Headache and Epidural Blood Patch rates. Failure rate in Epidrum group was 9\\/150 (6%) vs 0 (0%) in the Control group (P = 0.003). There were four (2.66%) accidental dural punctures in the Epidrum group and none in the Control group (P = 0.060), and 2 epidurals out of 150 (1.33%) in Epidrum group were re-sited, versus 3\\/150 (2%) in the control group (P = 1.000). The results of our study do not suggest that using Epidrum improves success or reduces morbidity.

  18. COMPARATIVE STUDY OF EPIDURAL BUPIVACAINE AND BUPIVACINE WITH NEOSTIGMINE

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    Pavani

    2015-05-01

    Full Text Available BACKGROUND: Many drugs have been used to prolong analgesic effects of epidural local anesthetics. These are called adjuvants. We studied the epidural effect of Neostigmine when adminstered with Bupivacaine in comparison with Bupivacaine . OBJECTIVE: The objective for the study was to find a drug which enhances the onset of action, increases the duration of action of the local anesthetic with minimal or no side effects, instead of increasing the dose of local anaesthetic. MATERIALS AND METHODS: A prospecti ve study was conducted on 100 adult patients, selected at random of either sex, of age between 20 - 65 years and belonging to ASA grade I or II. The study was designed to compare the effects of epidural Neostigmine with Bupivacaine and epidural Bupivacaine u sed alone with regard to onset, duration of analgesia, hemodynamic stability and level of anaesthesia. Patients were divided into two groups of 50 each. Group I received 19ml of 0.5% Bupivacaine+1ml of normal saline. Group II received 19ml of 0.5% Bupivaca ine+100μg of Neostigmine in 1ml of normal saline. In the operating room the patients were assessed for time of onset of analgesia, duration of anaesthesia, level of analgesia and complications. RESULTS : The addition of Neostigmine resulted in significant r apid onset of action, longer duration of analgesia and motor blockade. There was no incidence of respiratory depression, pruritus, fluctuations in blood pressure, or change in pulse rate, except one patient who developed bradycardia. CONCLUSION : Co adminis tration of epidural Neostigmine and Bupivacaine appears to be a useful technique for epidural anaesthesia as it provides faster onset, longer duration of action and haemodynamic stability.

  19. Comparison thoracic epidural and intercostal block to improve ventilation parameters and reduce pain in patients with multiple rib fractures.

    Science.gov (United States)

    Hashemzadeh, Shahryar; Hashemzadeh, Khosrov; Hosseinzadeh, Hamzeh; Aligholipour Maleki, Raheleh; Golzari, Samad E J; Golzari, Samad

    2011-01-01

    Chest wall blunt trauma causes multiple rib fractures and will often be associated with significant pain and may compromise ventilator mechanics. Analgesia has great roll in rib fracture therapies, opioid are useful, but when used as sole agent may require such high dose that they produce respiratory depression, especially in elderly .the best analgesia for a severe chest wall injury is a continuous epidural infusion of local anesthetic. This provides complete analgesia allowing inspiration and coughing without of the risk of respiratory depression. sixty adult patients who with multiple rib fractures were enrolled in this study. They were divided into Group A or thoracic epidural with bupivacaine 0.125 % +1mg/5ml morphine and group B or intercostal block with 0.25% bupivacaine. The patients were assessed through ICU and hospital stay length, ventilation function tests. Pain score among the patients was measured with verbal rating scale, before and after administration of the analgesia. We found a significant improvement in ventilatory function tests during the 1st, 2nd, and 3rd days after epidural analgesia compared with the intercostal block (P pain at rest and pain caused by coughing and deep breathing in group A compared group B... ICU and hospital stay markedly reduced in Group A. thoracic epidural analgesia is superior to intercostals block regarding pain relief of rib fractures. Patients who received epidural analgesia had significantly lower pain scores at all studied times.

  20. Developments in labour analgesia and their use in Australia.

    Science.gov (United States)

    Eley, V A; Callaway, L; van Zundert, A A

    2015-07-01

    Since the introduction of chloroform for labour analgesia in 1847, different methods and medications have been used to relieve the pain of labour. The use of heavy sedative medication in the early 1900s was encouraged by enthusiastic doctors and by women empowered by the women's suffrage movement in America. Nitrous oxide by inhalation has been used in Australia since the 1950s and improved methods of administration have made this method of analgesia safe and practical. Caudal epidural analgesia and lumbar epidural analgesia were first made popular in America and by the 1970s these techniques were more widely available in Australia. In 1847, physicians and the public were unsure whether relieving labour pains was the 'right' thing to do. However, many medical and social changes have occurred thanks to the clinical connection between Australia and the United Kingdom and those first settlers to land on Australian shores. Thanks to this historical connection, in today's Australia there is no question that women should use analgesia as a pain relief if they wish. Currently, the majority of women worldwide use some form of analgesia during labour and different methods are widely available. This paper discusses the four milestones of the development of obstetric analgesia and how they were introduced into patient care in Australia.

  1. Spinal and epidural anesthesia

    Science.gov (United States)

    ... you epidural or spinal anesthesia is called an anesthesiologist. First, the area of your back where the ... Chan VWS. Spinal, epidural, and caudal anesthesia. In: Miller RD, ed. Miller's Anesthesia . 8th ed. Philadelphia, PA: ...

  2. Epidural anesthesia in agoutis (Dasyprocta azarae

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    Leandro Luis Martins

    2010-06-01

    Full Text Available In this research, the epidural anesthesia technique in nulliparous and non non-nulliparous submitted to ovarysalpingohysterectomy was studied. These are rodents belonging to the “Missina Palmeira Zancaner” municipal zoo of catanduva in São Paulo. The tranquilizationwas achieved using azaperone (4mg/kg and meperidine (4mg/kg followed by injection of cetamine (20mg/kg and xylazine (0.4mg/kg, intramuscularly from the same syringe. Subsequently, lidocaine (5mg/kg was injected into the lumbosacral space. The time of latency of the anesthesic association (4.0±1.51min, time of latency of epidural lidocaine (6.87±2.35min and time of analgesia (115.0±12.49min were analyzed, in addition to rectal temperature, which decreased 2.12±0.86°C on average from the beginning of the anesthesia to the end of its effective time. All animals recovered satisfactorily without presenting signs of excitation or complications due to the epidural tecnique. It was concluded that the balanced anesthesia tecnique provided adequate analgesia during a time considered sufficient for several procedures, by means of low doses of xylazine and ketamine.

  3. Tachyphylaxis associated with repeated epidural injections of lidocaine is not related to changes in distribution or the rate of elimination from the epidural space

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    Mogensen, T.; Simonsen, L.; Scott, N.B.; Henriksen, J.H.; Kehlet, H. (Univ. of Copenhagen (Denmark))

    1989-08-01

    The relationship between tachyphylaxis (measured as a decrease in the rate of regression of sensory levels of analgesia) during repeated epidural injections of lidocaine and both the distribution of lidocaine within the epidural space (as measured by spread of simultaneous injection of the tracer technetium-99m diethylenetriaminepentaacetate (99mTc-DTPA)) and elimination of lidocaine from the epidural space (as measured by serum concentrations of lidocaine) was investigated in 18 patients undergoing minor surgery during lumbar epidural analgesia. Twelve patients received four injections of 20 mL of 2% lidocaine at 2-hr intervals. Epidural distribution was assessed by injection of 99mTc-DTPA diluted in saline on the preoperative day and diluted in an equal volume of 2% lidocaine on the morning before surgery and again after the fourth injection of lidocaine 6 hr later. The distribution of 99mTc-DTPA in the epidural space was unchanged during the three measurements despite significant tachyphylaxis in both sensory analgesia and motor blockade (11 of 12 patients had sensory analgesia 2 hr after the first injection in contrast to only 3 of 12 patients during the third injection). In another six patients 20 mL of 2% lidocaine were injected three times at 2-hr intervals before surgery, with measurements of serum concentrations of lidocaine after the first and last injections. Despite tachyphylaxis (no patient had sensory analgesia 2 hr after the third injection), there was no difference in the rate of disappearance of lidocaine from the epidural space as assessed by plasma lidocaine concentration curves during the first and third injection (0.5 +/- 0.1 and 0.3 +/- 0.04 microgram.mL-1.min-1, respectively).

  4. Apakah Epidural Preemtif Menghambat Stres Pembedahan dengan Sempurna?

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    Muh. Rumli Ahmad

    2013-09-01

    Full Text Available Preemptive analgesia is initiating an analgesic regimen before the onset of the noxious stimulus. Damages to the tissue caused by surgical trauma generate noxious response conveyed to the central nervous system (CNS by two pathways, neural pathway and circulatory pathway. This study is a double- blinded clinical trial that included 48 patients undergoing lower extremity orthopedic surgery. The subjects were divided into two groups: group I (n=24 received 10 mL bupivacaine 0.25% from epidural route, and group II (n=24 received 10 mL NaCl 0.9% from epidural route as the control group before induction of anesthesia. Both groups were anesthetized under general anesthesia. Group I received 5 mL bupivacaine 0,5% every 90 minutes and group II received 5 mL NaCl 0,9 with similar time intraoperatively. Post-operatively, both groups received continuous bupivacaine 0,25% 4 mL/ hour until 24 hours after surgery. Measurements of cytokine levels: tumor necrosis factor-α (TNF-α, interleukin- 1β (IL-1β, IL-6 and IL-10 were done before induction of anesthesia, in the early post-operative period, at 4, 8, and 24 hours after surgery. Group I showed lower level proinflammatory cytokines level compared with group II but the difference was not statistically significant (p>0.05. The level of anti-inflammatory cytokine was higher in group I, but the difference was not statistically significant (p>0.05. Pain intensity at 4 hours, 8 hours, 24 jam hours post operative was lower significantly (p0.05 excepst at early postoperative period (p<0.05. Generally, preemptive epidural analgesia was able to suppress the cytokine responses, but not completely. In conclusion, preemptive epidural analgesia is associated with better analgesia and better hemodynamic stability compared without preemptive epidural, but unable to suppress the production of proinflammatory and anti-inflammatory cytokines.

  5. Myelopathy with syringomyelia following thoracic epidural anaesthesia.

    Science.gov (United States)

    Aldrete, J A; Ferrari, H

    2004-02-01

    Under general anaesthesia and muscle relaxation, a thoracic epidural catheter was inserted at the T8-T9 level in a 7-year-old boy scheduled to have a Nissen fundoplication to provide postoperative analgesia. After 4 ml of lignocaine 1.5% was injected through the catheter, hypotension resulted. Fifty-five minutes later 5 ml of bupivacaine 0.25% produced the same effect. In the recovery room a similar injection resulted in lower blood pressure and temporary apnoea. Sensory and motor deficits were noted the next day and four days later magnetic resonance imaging demonstrated spinal cord syringomyelia extending from T5 to T10. Four years later, dysaesthesia from T6 to T10 weakness of the left lower extremity and bladder and bowel dysfunction persist. The risks of inserting thoracic epidural catheters in patients under general anaesthesia and muscle relaxation are discussed, emphasising the possibility of spinal cord injury with disastrous consequences.

  6. Tachyphylaxis associated with repeated epidural injections of lidocaine is not related to changes in distribution or the rate of elimination from the epidural space

    DEFF Research Database (Denmark)

    Mogensen, T; Simonsen, L; Scott, N B

    1989-01-01

    technetium-99m diethylenetriaminepentaacetate [99mTc-DTPA]) and elimination of lidocaine from the epidural space (as measured by serum concentrations of lidocaine) was investigated in 18 patients undergoing minor surgery during lumbar epidural analgesia. Twelve patients received four injections of 20 mL of 2......% lidocaine at 2-hr intervals. Epidural distribution was assessed by injection of 99mTc-DTPA diluted in saline on the preoperative day and diluted in an equal volume of 2% lidocaine on the morning before surgery and again after the fourth injection of lidocaine 6 hr later. The distribution of 99mTc-DTPA...

  7. CLINICAL EVALUATION OF EPIDURAL ADMINISTRATION OF MORPHINE, FENTANYL, METHADONE, LIDOCAINE AND LIDOCAINE WITH EPINEPHRINE IN CATTLE

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    A. Tabatabaei Naeine, A. Rezakhani and J. Fazlinia

    2004-01-01

    Full Text Available The purpose of this study was to determine the analgesic efficacy and clinical effects of morphine, fentanyl, methadone, lidocaine, lidocaine with epinephrine and saline (control when injected epidurally into the caudal epidural space in cattle. Epidural analgesia was achieved in five cattle on five successive occasions at weekly intervals. Analgesia was defined as a lack of response to hemostat pressure and pinprick in the skin of the perineal area and ventral aspect of the tail. The results demonstrated that while epidural lidocaine and lidocaine with epinephrine decreased the response to hemostat and pinprick compared to control, there was no reduction in response after the administration of morphine, methadone or fentanyl. Heart rate, pulse and respiratory rates were not significantly altered by any of the drugs. Neither did the drugs produce any change in the electrocardiogram (ECG of the animals.

  8. Epidural tramadol via intraoperatively placed catheter as a standalone analgesic after spinal fusion procedure: An analysis of efficacy and cost.

    Science.gov (United States)

    Ilangovan, Vijaysundar; Vivakaran, Thanga Tirupathi Rajan; Gunasekaran, D; Devikala, D

    2017-01-01

    This was a prospective analysis of epidural tramadol as a single analgesic agent delivered through intraoperatively placed epidural catheter for postoperative pain relief after spinal fusion procedures in terms of efficacy and cost. Twenty patients who underwent spinal fusion procedures were included in the study. After completion of the procedure, an epidural catheter was placed at the highest level of exposed dura and brought out through a separate tract. Postoperatively, tramadol was infused into the epidural space via the catheter at a dose of 1 mg/kg diluted in 10 ml of saline. The dosage frequency was arbitrarily fixed at every 6 h during the first 2 days and thereafter reduced to every 8 h after the first 2 days till day 5. Conventional intravenous analgesics were used only if additional analgesia was required as assessed by visual analog scale (VAS). Patients' VAS score was assessed every 4 h from the day of surgery. Patients with a VAS score of 6 or more were given additional analgesia in the form of intravenous paracetamol. Of the twenty patients, eight patients needed additional analgesia during the first 24 h and none required additional analgesia after the first 24 h. The median VAS score was 7 within the first 24 h and progressively declined thereafter. Epidural tramadol was noted to be many times cheaper than conventional parenteral analgesics. Epidural tramadol infusion is safe and effective as a standalone analgesic after open spinal fusion surgery, especially after the 1(st) postoperative day. Intraoperative placement of the epidural catheter is a simple way of delivering tramadol to the epidural space. The cost of analgesia after spinal fusion surgery can be reduced significantly using epidural tramadol alone.

  9. Epidural tramadol via intraoperatively placed catheter as a standalone analgesic after spinal fusion procedure: An analysis of efficacy and cost

    Science.gov (United States)

    Ilangovan, Vijaysundar; Vivakaran, Thanga Tirupathi Rajan; Gunasekaran, D.; Devikala, D.

    2017-01-01

    Objective: This was a prospective analysis of epidural tramadol as a single analgesic agent delivered through intraoperatively placed epidural catheter for postoperative pain relief after spinal fusion procedures in terms of efficacy and cost. Materials and Methods: Twenty patients who underwent spinal fusion procedures were included in the study. After completion of the procedure, an epidural catheter was placed at the highest level of exposed dura and brought out through a separate tract. Postoperatively, tramadol was infused into the epidural space via the catheter at a dose of 1 mg/kg diluted in 10 ml of saline. The dosage frequency was arbitrarily fixed at every 6 h during the first 2 days and thereafter reduced to every 8 h after the first 2 days till day 5. Conventional intravenous analgesics were used only if additional analgesia was required as assessed by visual analog scale (VAS). Results: Patients’ VAS score was assessed every 4 h from the day of surgery. Patients with a VAS score of 6 or more were given additional analgesia in the form of intravenous paracetamol. Of the twenty patients, eight patients needed additional analgesia during the first 24 h and none required additional analgesia after the first 24 h. The median VAS score was 7 within the first 24 h and progressively declined thereafter. Epidural tramadol was noted to be many times cheaper than conventional parenteral analgesics. Conclusion: Epidural tramadol infusion is safe and effective as a standalone analgesic after open spinal fusion surgery, especially after the 1st postoperative day. Intraoperative placement of the epidural catheter is a simple way of delivering tramadol to the epidural space. The cost of analgesia after spinal fusion surgery can be reduced significantly using epidural tramadol alone. PMID:28149082

  10. Analgesia preemptiva nas cirurgias da coluna lombossacra: estudo prospectivo e randomizado Analgesia preventiva en las cirugías de la columna lumbosacra: estudio prospectivo y aleatorio Preemptive analgesia in lumbosacral spine surgeries: prospective randomized study

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    Augustin Malzac

    2009-06-01

    Full Text Available OBJETIVO: Analisar a eficácia da analgesia preemptiva pelo método da administração de analgésicos antes e após o início do estímulo doloroso operatório, comparando-as. A melhora do quadro doloroso pós-operatório nas cirurgias da coluna vertebral no segmento lombossacro, por via posterior, não tem sido completamente investigada. MÉTODOS: Sessenta e dois pacientes submetidos à microdiscectomia ou microdescompressão, em um único nível, na coluna lombossacra, foram divididos em três grupos, 20 pacientes no primeiro (A não receberam qualquer substância analgésica (controle. Vinte e dois no segundo (B, os quais foram submetidos à injeção epidural, 20 minutos antes da incisão cirúrgica, contendo 10 mL de marcaína e morfina. No terceiro e no último grupo (C com vinte pacientes, foi injetado, com auxílio de um cateter, no espaço epidural, as mesmas drogas do grupo B, através da incisão antes do fechamento da ferida operatória. Os pacientes foram examinados durante as primeiras 24 horas com auxílio da escala verbal de dor. RESULTADOS: Os três grupos foram comparados quanto à idade, sexo, nível e tempo cirúrgico. Os dados não obedeceram a uma distribuição Gaussiana, o teste não paramétrico de Mann-Whitney foi adotado para análise estatística. Desta maneira, os valores da escala verbal de dor, em todos os intervalos de tempo, foram significativamente baixos (pOBJETIVO: analizar la eficacia y comparar la analgesia preventiva por el método de la administración de analgésicos antes y después del inicio del estímulo doloroso operatorio. La mejoría del cuadro doloroso postoperatorio en las cirugías de la columna vertebral en el segmento lumbosacro, por vía posterior, no ha sido completamente investigada. MÉTODOS: sesenta y dos pacientes sometidos a la microdisección o microdescompresión, en un único nivel, en la columna lumbosacra fueron divididos en tres grupos. Veinte pacientes en el primer grupo (A no

  11. COMPARISION OF TWO DRUG COMBINATIONS FOR LABOUR ANALGESIA, AND ITS EFFECT ON PATIENT SATISFACTION, DURATION OF LABOUR AND FETAL OUTCOME

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    Jaideep

    2014-09-01

    Full Text Available : BACKGROUND: Epidural is now established and accepted method to relief labour pain. This study intended to comparison of two drug combinations in labour analgesia and its effect on duration of labour, maternal satisfaction and fetal outcome. Combined epidural infusion of bupivacaine + fentanyl would result in analgesia superior to that provided by a continuous epidural infusion of a similar concentration of Bupivacaine alone. AIMS AND OBJECTIVE: To compare the efficacy of two drug combinations for labour analgesia, and its effect on patient satisfaction, duration of labour and fetal outcome. MATERIALS AND METHODS: Study design – comparative randomized controlled study. Sample size: For this study 50 pregnant women were randomly selected and divided into two groups. GROUP I: Control Group (Continuous epidural infusion of Bupivacaine CEI: 25 parturient who were given a bolus of 0.1% Bupivacaine + 20mcg Fentanyl followed by infusion of 0.0625% Bupivacaine epidurally. GROUP II: Study Group (Continuous epidural infusion of Bupivacaine with Fentanyl CEIF: 25 parturients who were given a bolus of 0.1% Bupivacaine + 20mcg Fentanyl followed by infusion of 0.0625% Bupivacaine + 0.0001% Fentanyl epidurally. Duration of labour, Analgesia, maternal satisfaction, fetal outcome was assessed by different scales like bromage scale, visual analogue scale, APGAR score and pin prick method are used. Side effects and complications, if present were recorded.

  12. Efficacy of epidural administration of morphine with bupivacaine for orthopaedic surgery in sheep

    OpenAIRE

    Durej M.; Ledecký V.; Michalák D.; Hluchý M.; Kòazovický D.

    2012-01-01

    The aim of the study was to test the hypothesis that epidural administration of morphine with bupivacaine provides more intense and sufficient perioperative analgesia compared with parenterally administrated butorphanol during orthopaedic surgery. Sheep were assigned to group C (control group, 6 sheep) and group E (epidural, 5 sheep). Sheep from group C were pre-medicated with midazolam (0.3 mg/kg, i.m.) and butorphanol (0.2 mg/kg, i.m.). Propofol was used ...

  13. Sonographic evaluation of epidural and intrathecal injections in cats.

    Science.gov (United States)

    Otero, Pablo E; Verdier, Natali; Zaccagnini, Andrea S; Fuensalida, Santiago E; Sclocco, Matias; Portela, Diego A; Waxman, Samanta

    2016-11-01

    To describe the ultrasonographic anatomy of the caudal lumbar spine in cats and to detect ultrasound (US) signs associated with epidural or intrathecal injection. Prospective, clinical study. Twenty-six client-owned cats. Transverse (position 1) and parasagittal (position 2) two-dimensional US scanning was performed over the caudal lumbar spine in all cats. Midline distances between the identified structures were measured. Cats assigned to epidural injection (group E, n = 16) were administered a bupivacaine-morphine combination confirmed by electrical stimulation. Cats assigned to intrathecal injection (group I, n = 10) were administered a morphine-iohexol combination injected at the lumbosacral level and confirmed by lateral radiography. The total volume injected (0.3 mL kg(-1) ) was divided into two equal aliquots that were injected without needle repositioning, with the US probe in positions 1 and 2, respectively. The presence or absence of a burst of color [color flow Doppler test (CFDT)], dural sac collapse and epidural space enlargement were registered during and after both injections. US scanning allowed measurement of the distances between the highly visible structures inside the spinal canal. CFDT was positive for all animals in group E. In group I, intrathecal injection was confirmed in only two animals, for which the CFDT was negative; seven cats inadvertently and simultaneously were administered an epidural injection and showed a positive CFDT during the second aliquot injection, and the remaining animal was administered epidural anesthesia and was excluded from the CFDT data analysis. Dural sac collapse and epidural space enlargement were present in all animals in which an epidural injection was confirmed. US examination allowed an anatomical description of the caudal lumbar spine and real-time confirmation of epidural injection by observation of a positive CFDT, dural sac collapse and epidural space enlargement. © 2016 Association of

  14. Substituição da agulha isolada para eletroneuroestimulação pela agulha metálica de cateter intravenoso, na verificação da punção epidural, em cães

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    E.A. Tudury

    2013-02-01

    Full Text Available Utilizou-se o eletroneuroestimulador como um meio adequado para confirmação do posicionamento da ponta de agulhas isoladas no espaço epidural lombossal, por meio de pequenas estimulações elétricas que provocam contrações dos músculos inervados, empregando-se agulha de cateter intravenoso em vez de agulha isolada para a eletroneuroestimulação. Foram utilizados 40 cães para procedimentos cirúrgicos ortopédicos, abdominais ou retroumbilicais que necessitassem de bloqueio epidural. Durante a introdução gradativa da agulha no canal vertebral lombossacral, estímulos elétricos de 1,5 a 0,5mA foram aplicados. Diante de contrações musculares em membros pélvicos, cauda e/ou ânus, as quais foram consideradas respostas condizentes com o correto posicionamento da agulha no espaço epidural, estimulando raízes da cauda equina, procedeu-se à administração da associação de lidocaína, bupivacaína e tramadol. Constatou-se a adequada anestesia epidural mediante relaxamento do esfíncter anal, ausência dos reflexos patelares e flexor e a analgesia na área cirúrgica abdominal. Conclui-se que o método foi eficaz para a confirmação do correto posicionamento da agulha no espaço epidural durante a realização dessa anestesia regional em cães.

  15. Is the combination of epidural clonidine–levobupivacaine has same analgesic efficacy and safety as the combination fentanyl–levobupivacaine after radical cystectomy?

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    Essam A. Mahran

    2014-04-01

    Conclusion: We concluded that both clonidine and fentanyl can be used as effective additive to epidural levobubivacaine for postoperative analgesia after radical cystectomy with no significant difference between them in vital signs, analgesic, sedative effects and safety profile on adding each of them in doses not exceeding 20 μg/h to epidural continuous levobupivacaine infusion.

  16. Dexmedetomidine and clonidine in epidural anaesthesia: A comparative evaluation

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    Sukhminder Jit Singh Bajwa

    2011-01-01

    Full Text Available Efforts to find a better adjuvant in regional anaesthesia are underway since long. Aims and objectives are to compare the efficacy and clinical profile of two α-2 adrenergic agonists, dexmedetomidine and clonidine, in epidural anaesthesia with special emphasis on their sedative properties and an ability to provide smooth intra-operative and post-operative analgesia. A prospective randomized study was carried out which included 50 adult female patients between the ages of 44 and 65 years of (American Society of Anaesthesiologists ASAI/II grade who underwent vaginal hysterectomies. The patients were randomly allocated into two groups; ropivacaine + dexmedetomidine (RD and ropivacaine + clonidine (RC, comprising of 25 patients each. Group RD was administered 17 ml of 0.75% epidural ropivacaine and 1.5 μg/kg of dexmedetomidine, while group RC received admixture of 17 ml of 0.75% ropivacaine and 2 μg/kg of clonidine. Onset of analgesia, sensory and motor block levels, sedation, duration of analgesia and side effects were observed. The data obtained was subjected to statistical computation with analysis of variance and chi-square test using statistical package for social science (SPSS version 10.0 for windows and value of P 0.05. Dexmedetomidine is a better neuraxial adjuvant compared to clonidine for providing early onset of sensory analgesia, adequate sedation and a prolonged post-operative analgesia.

  17. 硬膜外泵入布托啡诺复合小剂量氯胺酮在分娩镇痛中的应用%Epidural in fasion butorphanol plus low dose of ketamine in labor analgesia

    Institute of Scientific and Technical Information of China (English)

    邓燕; 张勇; 王开祥

    2009-01-01

    目的 观察硬膜外持续泵入布托啡诺复合小剂量氯胺酮用于分娩镇痛的效果及其对分娩过程和胎儿的影响.方法 选择单胎足月初产妇60例,随机分为两组.A组(对照组)30例,硬膜外持续泵入0.1%罗哌卡因+芬太尼0.15μg/ml,泵速4 ml/h;B组(观察组)30例,硬膜外持续泵入布托啡诺0.1 mg/kg+氟胺酮0.7 mg/kg,泵速4 ml/h.连续监测呼吸,循环情况;采用视觉模拟疼痛评分(VAS)评估镇痛效应;运动神经阻滞程度按改良的Bromage标准进行测定;观察记录产程进展宫缩及胎儿情况、新生儿情况及不良反应.结果 A、B两组的VAS评分差异无统计学意义(P>0.05).新生儿各时点的Apgar评分两组间比较差异也无统计学意义(P>0.05).A组第二产程(67±51)min,较B组(41±20)min有所延长(P<0.05).产妇的生命体征、宫缩、胎儿及运动神经阻滞程度,两组差异无统计学意义.结论 硬膜外泵入布托啡诺复合小剂量氨胺酮可安全有效地应用于分娩镇痛.%Objective To evaluate the analgesic efficacy and safety of butorphanol combined with low dose of ketamine for labor analgesia.Methods Sixty ASA Ⅰ-Ⅱ full term primigravidae in active labor who had a single fetus with vertex presentation and were expected to have avaginal deavery were randomly divided into two groups;control group (group A) received with ropicanine and fentany (n=30);observation group (group B) received with butorphanol 0.1 mg/kg in combination with ketamie 0.7 mg/kg in 100 ml normal saline.Both infusion in a rate of 4 ml/h.The intensity of pain was evaluated by patients using VAS and motor function was assessed using modified bromage score.The vital signs (BP,HR,SpO2),fetal neart rate,labor process,mode of delivery.Apgar score of neonates and side effects of analgesia were recorded.Results There was no significant differece in VAS score and fetal apgar score between group A and B(P>0.05) ;the duration of second stage of labor was longer

  18. Analgesia epidural continua de buprenorfina en bomba elastomérica vs tramadol a gravedad en venoclisis para control de dolor postquirúrgico en fijación transpedicular de columna lumbar. Hospital "Dr. Teodoro Maldonado Carbo".

    OpenAIRE

    Aguilar Alvarado, Joffre Alexander

    2015-01-01

    El dolor postoperatorio significativo requiere una estancia hospitalaria prolongada, aumento de medicamentos, e insatisfacción de los pacientes por lo que el control del dolor es fundamental. Los opioides son generalmente los más utilizados pero su uso se asocia a una mayor incidencia de complicaciones postoperatorias. Los anestesiólogos están recurriendo a técnicas analgésicas para el manejo del dolor durante el perioperatorio, para minimizar los efectos adversos de estos analgé...

  19. Epidural fibrosis after permanent catheter insertion and infusion.

    Science.gov (United States)

    Aldrete, J A

    1995-11-01

    Forty-six permanent epidural catheters and life-port units were implanted in 43 patients with severe, recurrent low back pain who had been considered not to be candidates for surgical intervention and in whom other therapeutic modalities had failed. Eight cases developed epidural fibrosis (EF). For analgesia, patients received either infusions with preservative-free solutions of fentanyl and bupivacaine or daily boluses of morphine and bupivacaine. Catheters remained from 75 days to 433 days. Signs of EF appeared from 21 days to 320 days after implantation. Pain at injection or resistance to injection were initial manifestations of EF, followed by poor, and eventually, nil analgesic effect. The epidural catheters were made of either polyamide, silicone, or polyurethane. Epidurograms revealed encapsulation, narrowing, and loculation of epidural space with gradually reduced spread of the contrast material. The occurrence of EF limits the permanency of implanted epidural catheters. The infusate does not cause this complication, which appears to be a foreign body reaction due to the presence of the catheter in the epidural space.

  20. Effect of sufentanil combined with different concentrations of ropivacaine for labor analgesia on maternal

    Institute of Scientific and Technical Information of China (English)

    Han-He Wang; Min-Jia Jiang; Wan-Dong Liao

    2016-01-01

    Objective:To study the effect of sufentanil combined with different concentration of ropivacaine for stepped analgesia on stage of labor, stress indexes and blood coagulation function.Methods:A total of 178 cases of full-term singleton primiparas who awaited delivery and received epidural labor analgesia in our hospital from January 2015 to June 2016 were selected and randomly divided into stepped analgesia group and routine analgesia group, and the stage of labor, levels of stress hormones and pain mediators during childbirth and blood coagulation function indexes after childbirth were observed between two groups.Results: The duration of latent phase of labor of stepped analgesia group was shorter than that of routine analgesia group while the duration of active phase of labor, the duration of second stage of labor and the duration of third stage of labor were not significantly different from those of routine analgesia group; serum PRL level of stepped analgesia group was significantly higher than that of routine analgesia group while PA, NE, E, DYN,β-EP, SP, PGE2, 5-HT, TF, TFPI, FPA, AT-III and DD levels were not significantly different from those of routine analgesia group.Conclusions: Sufentanil combined with different concentration of ropivacaine for stepped analgesia is with equivalent effect to routine analgesia, and can shorten the latent phase of labor and reduce the inhibitory effect of pain on prolactin without affecting the degree of stress during childbirth and the blood coagulation function after childbirth.

  1. Infections following epidural catheterization

    DEFF Research Database (Denmark)

    Holt, MS; Andersen, SS; Andersen, Ove

    1995-01-01

    Seventy-eight patients with culture-positive epidural catheters, were studied. Fifty-nine had symptoms of exit site infection and 11 patients had clinical meningitis, two of whom also had an epidural abscess. This corresponds to a local infection incidence of at least 4.3% and an incidence of cen...... frequently than the others. We discuss the symptoms and diagnosis of spinal epidural abscess and suggest a proposal for prophylactic and diagnostic guidelines for epidural catheter-related infections. Comment in: J Hosp Infect. 1997 Mar;35(3):245....

  2. Epidural anaesthesia for caesarean section in pituitary dwarfism.

    Science.gov (United States)

    Li, Hongbo; Li, Ruihua; Lang, Bao

    2017-04-01

    We describe the anaesthetic management for caesarean section in a 32-year-old patient with pituitary dwarfism. In addition to supportive treatment, we offered a postoperative epidural analgesia pump. The patient recovered well without any complications. Copyright © 2016 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

  3. Effect of epidural anesthesia using ropivacaine combined with remifentanil on delivery

    Institute of Scientific and Technical Information of China (English)

    Wen Cheng

    2016-01-01

    Objective:Tostudy the ropivacaine combined with remifentanil on analgesic effect and safety of painless labor requirements of maternal epidural anesthesia.Methods:Hospital obstetrics and gynecology scheduled for painless delivery of maternal were selected. 80 cases (analgesic group, the use of ropivacaine epidural analgesia with remifentanil), did not use any analgesia 80 cases of childbirth women as controls group, two groups of mothers underwent index difference childbirth pain were observed during childbirth, birth outcomes and other health care workers with the help of the same group under midwifery.Results:VAS score between T0 time analgesia group and the control group was not statistically significant; in the analgesic, T4, T5, T6 moments analgesia group VAS scores were significantly lower than T1, T2, T3 in the control group. Significantly lower than the control group the first stage of labor analgesia group, significantly longer than the second stage of labor analgesia group control group, two groups of maternal third stage of labor was no significant difference. Mode of delivery between the two groups, birth weight, the first and second 1 min, 5 min Apgar scores were not significantly different.Conclusion: Ropivacaine remifentanil requirements for painless childbirth maternal epidural anesthesia can significantly reduce maternal childbirth pain without causing adverse effects on childbirth and newborns.

  4. Tachyphylaxis associated with repeated epidural injections of lidocaine is not related to changes in distribution or the rate of elimination from the epidural space

    DEFF Research Database (Denmark)

    Mogensen, T; Simonsen, L; Scott, N B

    1989-01-01

    technetium-99m diethylenetriaminepentaacetate [99mTc-DTPA]) and elimination of lidocaine from the epidural space (as measured by serum concentrations of lidocaine) was investigated in 18 patients undergoing minor surgery during lumbar epidural analgesia. Twelve patients received four injections of 20 mL of 2......% lidocaine at 2-hr intervals. Epidural distribution was assessed by injection of 99mTc-DTPA diluted in saline on the preoperative day and diluted in an equal volume of 2% lidocaine on the morning before surgery and again after the fourth injection of lidocaine 6 hr later. The distribution of 99m......L of 2% lidocaine were injected three times at 2-hr intervals before surgery, with measurements of serum concentrations of lidocaine after the first and last injections. Despite tachyphylaxis (no patient had sensory analgesia 2 hr after the third injection), there was no difference in the rate...

  5. Effects of combined perioperative epidural bupivacaine and morphine, ibuprofen, and incisional bupivacaine on postoperative pain, pulmonary, and endocrine-metabolic function after minilaparotomy cholecystectomy

    DEFF Research Database (Denmark)

    Dahl, J B; Hjortsø, N C; Stage, J G

    1994-01-01

    cholecystectomy improves pain relief in the immediate postoperative period, compared to intramuscular morphine. Pulmonary and endocrine-metabolic function is not changed to such degree after minicholecystectomy that epidural analgesia can be demonstrated to have beneficial effects.......BACKGROUND AND OBJECTIVES. The study investigates the effects of combined perioperative continuous epidural bupivacaine and morphine, ibuprofen, and incisional bupivacaine, compared with intermittent systemic morphine, ibuprofen, and incisional bupivacaine, on postoperative pain, respiratory...... function, and endocrine-metabolic alterations associated with minilaparotomy cholecystectomy. METHODS. Thirty-two patients scheduled for cholecystectomy, performed through a minilaparotomy, were randomized to receive general anesthesia with pre- and postoperative thoracic (T7-9) epidural analgesia...

  6. Convalescence and hospital stay after colonic surgery with balanced analgesia, early oral feeding, and enforced mobilisation

    DEFF Research Database (Denmark)

    Møiniche, S; Bülow, Steffen; Hesselfeldt, Peter;

    1995-01-01

    unselected patients (median age 69 years) undergoing colonic resection. INTERVENTIONS: Patients received combined epidural and general anaesthesia during operations and after operation were given continuous epidural bupivacaine 0.25%, 4 ml hour and morphine 0.2 mg hour, for 96 hours and oral paracetamol 4 g......OBJECTIVE: To evaluate the combined effects of pain relief by continuous epidural analgesia, early oral feeding and enforced mobilisation on convalescence and hospital stay after colonic resection. DESIGN: Uncontrolled pilot investigation. SETTING: University hospital, Denmark. SUBJECTS: 17...

  7. [Clinical anesthetic effects of epidural ropivacaine with tramadol].

    Science.gov (United States)

    Cai, Jin; Guo, Qu-Lian; Zou, Wang-Yuan

    2004-04-01

    To observe the anesthesic effects of epidural ropivacaine with tramadol during lower limbs surgery. Thirty patients (ASA I - II) scheduled for the lower limbs surgery were randomly divided into 2 groups with 15 patients in each group: group ropivacaine (R) and group ropivacaine with tramadol (T). The puncture was performed at the interspace of L2-3. Each patient was given 2% lidocaine 3 ml with 0.75% ropivacaine 10 ml which included NS 1 ml in Group R or tramadol 50 mg in Group T. The potency of analgesia, the time of sensation block to T12 and T10, the time to the highest plane of analgesia, the lasting time of analgesia, the degree of sedation, the degree of motor block, and the side effects were recorded and analyzed during anesthesia after the first dose. The time of sensation block which reached T12 and T10 and the time to the highest plane of analgesia decreased significantly in Group T than that in Group R (P 0.05). The epidural ropivacaine with tramadol enhanced the anesthetic effects of ropivacaine.

  8. Comparative study of epidural application of morphine versus gelfoam soaked in morphine for lumbar laminectomy

    Directory of Open Access Journals (Sweden)

    Sandeep Kundra

    2014-01-01

    Full Text Available Background: Epidural application of morphine has been used for postoperative analgesia following spine surgery but short duration of action of single application limits its widespread use. Materials and Methods: One hundred and fifty patients undergoing lumbar laminectomy were randomly allocated to two groups of 75 patients each. Anesthetic technique was standardized in both the groups. In Group I, at the completion of laminectomy, a 5 × 1-cm strip of gelfoam soaked in 5 mg morphine (1 mg/ml was contoured to be placed in the epidural space whereas, in group II, gelfoam soaked in saline was placed in the epidural space and 5 mg morphine (1mg/ml was instilled over the intact epidural space. Analgesic consumption for 48 hours, time-of first analgesic request, time of ambulation, time of discharge from post anesthesia care unit (PACU and hospital and adverse effects were recorded. The data was analyzed using appropriate statistical tests. Results: Mean analgesic consumption in 48 hours was significantly less in group I (8.47 ± 3.674 mg as compared to group II (24.80 ± 6.009 mg. Supplemental analgesia was requested at 30.03 ± 6.796 hours in Group I, vs 10.25 ± 2.243 in group II (P 0.01. Conclusion: Epidural application of morphine soaked in gelfoam is an effective method for prolonging the postoperative analgesia after spine surgery.

  9. Effect of epidural 0.25% bupivacaine on somatosensory evoked potentials to dermatomal stimulation

    DEFF Research Database (Denmark)

    Lund, C; Hansen, O B; Kehlet, H

    1989-01-01

    The effect of lumbar epidural analgesia with similar volumes (about 25 ml) of 0.25% and 0.5% bupivacaine on early (less than 0.5 seconds) somatosensory evoked potentials (SEPs) to electrical stimulation of the S1, L1, and T10 dermatomes was examined in two groups of ten patients. Level of sensory...

  10. Continuous Spinal Anesthesia for Obstetric Anesthesia and Analgesia

    Directory of Open Access Journals (Sweden)

    Ivan Veličković

    2017-08-01

    Full Text Available The widespread use of continuous spinal anesthesia (CSA in obstetrics has been slow because of the high risk for post-dural puncture headache (PDPH associated with epidural needles and catheters. New advances in equipment and technique have not significantly overcome this disadvantage. However, CSA offers an alternative to epidural anesthesia in morbidly obese women, women with severe cardiac disease, and patients with prior spinal surgery. It should be strongly considered in parturients who receive an accidental dural puncture with a large bore needle, on the basis of recent work suggesting significant reduction in PDPH when intrathecal catheters are used. Small doses of drug can be administered and extension of labor analgesia for emergency cesarean delivery may occur more rapidly compared to continuous epidural techniques.

  11. 罗比卡因与布比卡因用于小儿术后镇痛的比较%To compare the differences in analgesia effect and complication of the same concentrated ropivacaine and Bupivacaine after epidural anaesthesia in children

    Institute of Scientific and Technical Information of China (English)

    岳玲; 范荣

    2009-01-01

    目的 比较相同浓度的罗比卡因与布比卡因用于小儿硬膜外术后镇痛的镇痛效果和并发症.方法 选择60例行腰硬联合麻醉的腹部手术患儿随机分成两组行硬膜外术后镇痛,A组用0.1%罗比卡因,B组用0.1%布比卡因,每组分别复合芬太尼2 ug/ml,镇痛泵容量为100 ml,泵速为2 ml/h,维持镇痛时间48 h.观察指标有运动神经阻滞评分、手术后各时段的SpO2、BP、HR,OPS法镇痛效果评分、并发症情况.结果 A组和B组比较,下肢运动阻滞程度两者相比差异有统计学意义(P0.05),并发症两者相似(P>0.05).结论 0.1%罗比卡因复合芬太尼2 ug/ml具有同0.1%布比卡因复合芬太尼2 ug/ml同样的镇痛效应,而且对运动神经影响轻微,有利于患儿早期下床活动,用于小儿术后镇痛值得推广.%Objective To compare the differences in analgesia effect and complication of the same concentrated ropivacaine and Bupivacaine after epidural anaesthesia in children. Methods Divide 60 children randomly into group A and group B ,perform anagesia after epidural anaethesia with 0.1%ropivacaine in group A and 0.1% Bupivacaine in group B.Pump Fentanyl 2 ug/ml with the speed of 2 ml/h and the total dosage of 100 ml in 48 h simultaneously. The observation index includes motor nerve block score/SpO2,BP,HR in different periods after operation、anagesia effect score of OPS and complication. Results It has a significant difference in inferior extremity motor nerve block(P0.05) between the two groups. Conclusion 0.1% ropivacaine has the same level of anagesia effect as 0.1% Bupivacaine combinated by Fentanyl 2 ug/ml,and it has smaller influence on motor nerve.It is profit for children' early ambulation,so it is worth of generalization.

  12. Analgesia de parto em paciente com tetralogia de Fallot não corrigida: relato de caso Analgesia de parto en paciente con tetralogía de Fallot no corregida: relato de caso Labour analgesia in parturient with uncorrected tetralogy of Fallot: case report

    Directory of Open Access Journals (Sweden)

    Florentino Fernandes Mendes

    2005-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Embora a tetralogia de Fallot seja a mais comum das cardiopatias congênitas cianóticas, as publicações nacionais, relacionando essa doença com a prática anestésica são escassas. O objetivo deste relato é apresentar um caso de analgesia de parto em paciente portadora de tetralogia de Fallot não corrigida e diagnosticada durante a gestação. RELATO DO CASO: Paciente com 26 anos, 56 kg, 1,56 m, idade gestacional 32 semanas e 5 dias, com diagnóstico de tetralogia de Fallot realizado durante a gestação. Internou em trabalho de parto. A conduta obstétrica foi a de parto via baixa, sendo realizada analgesia através de bloqueio peridural com bupivacaína a 0,125% e fentanil (100 µg e colocação de cateter peridural. Após 1h30 minutos do início da analgesia, ocorreu o nascimento. O peso do recém-nascido foi 1485 g e o índice de Apgar 6 e 8 no primeiro e no quinto minutos, respectivamente. A paciente permaneceu estável e sem alterações hemodinâmicas e/ou eletrocardiográficas. CONCLUSÕES: A escolha da técnica anestésica é de fundamental importância no manuseio das pacientes com tetralogia de Fallot não corrigidas. Condições favoráveis do colo e boa dinâmica uterina, particularmente naquelas pacientes sem história de síncope, tornam-se imprescindíveis para uma boa indicação da analgesia de parto.JUSTIFICATIVA Y OBJETIVOS: Aunque la tetralogía de Fallot sea la más común de las cardiopatías congénitas cianóticas, las publicaciones nacionales, relacionando esa enfermedad con la práctica anestésica son escasas. El objetivo de este relato es presentar un caso de analgesia de parto en paciente portadora de tetralogía de Fallot no corregida y diagnosticada durante la gestación. RELATO DEL CASO: Paciente con 26 años, 56 kg, 1,56 m, edad gestacional 32 semanas y 5 días, con diagnóstico de tetralogía de Fallot realizado durante la gestación. Internó en trabajo de parto. La conducta

  13. Hemodynamic Changes during Epidural Anesthesia with Various Local Anesthetics

    Directory of Open Access Journals (Sweden)

    Ye. M. Shifman

    2008-01-01

    Full Text Available Central hemodynamic stability during gynecological laparoscopic operations remains an important problem of anes-thesiological monitoring. Subjects and methods. Fifty-eight patients who had undergone various gynecological laparoscopic operations were examined. According to the mode of anesthesia, the patients were divided into 2 groups: 1 29 patients who received epidural anesthesia with ropivacaine; 2 29 who had epidural anesthesia using lidocaine. The indices of cardiac performance (stroke volume, stroke index, and cardiac output, blood (diastolic, systolic, and mean pressure, vascular parameters (linear blood flow velocity, total peripheral vascular resistance were determined by volumetric compression oscillometry. Results. The study indicated that all the modes of anesthesia demonstrated the satisfactory condition of the cardiovascular system, but the highest stability of hemodynamic parameters was recorded in the epidural ropivacaine group. In this group, there were steady-state reductions in diastolic, systolic, mean blood pressures, and total vascular peripheral resistance and increases in stroke index, stroke volume, and linear blood flow velocity. Conclusion. Epidural anesthesia using ropivacaine during gynecological surgical endoscopic interventions is the method of analgesia causing minimal hemodynamic disorders. Key words: hemodynamics, epidural anesthesia, laparoscopic gynecological operations.

  14. Feasibility of whole-range epidural labor analgesia for parturient women with pregnancy-induced hypertension in natural delivery%全程硬膜外分娩镇痛用于妊娠期高血压产妇自然分娩可行性分析

    Institute of Scientific and Technical Information of China (English)

    齐俊巧; 张秀民; 邵俊涛; 吴侠; 郭丽魁; 李淑文

    2011-01-01

    目的 探讨全程硬膜外阻滞分娩镇痛对患有妊娠期高血压疾病产妇自然分娩结局及应激激素水平的影响.方法 选择妊娠期高血压疾病产妇80例,随机分为两组,各40例,全程分娩镇痛组(A组),活跃期分娩镇痛组(B组)行分娩镇痛,两组操作过程完全一致.采用视觉模拟疼痛评分(visual analogue score,VAS),记录镇痛前及镇痛后直至宫口开全时的疼痛评分,以及产程潜伏期、活跃期、第二产程、第三产程持续时间、宫缩药使用情况、分娩结局、产时出血量.产妇满意度及新生儿评分.两组分别于规律宫缩(T0),宫口开大3 cm(T1),宫口开全(T2)胎儿娩出(T3)抽取产妇静脉血,采用放射免疫法测定肾上腺素(adrenaline,ADR)皮质醇(cortisol,COR)的浓度,同时测定产妇血压,计算平均动脉压(mean arterial preasure,MAP).结果 镇痛前的VAS评分,A组低于B组(P0.05),缩宫素使用时间,A组高于B组(P0.05). However, there was significant difference in MAP and the concentrations of ADR and COR between stage Tt and To in group B ( P < 0. 05 ) . Conclusions Whole range epidural analgesia reduces stress reaction resulting from labor pain in parturient women with PIH, prevents the deterioration of PIH without increasing the rate of caesare-an section, shows fewer side effects and makes safer vaginal delivery of parturient women with PIH.

  15. Infections following epidural catheterization

    DEFF Research Database (Denmark)

    Holt, MS; Andersen, SS; Andersen, Ove

    1995-01-01

    patients with only local symptoms of infection. The microorganisms isolated from the tips of the epidural catheters were coagulase-negative staphylococci (41%), Staphylococcus aureus (35%), Gram-negative bacilli (14%) and others (10%). The Gram-negative bacilli and S. aureus caused serious infections more......Seventy-eight patients with culture-positive epidural catheters, were studied. Fifty-nine had symptoms of exit site infection and 11 patients had clinical meningitis, two of whom also had an epidural abscess. This corresponds to a local infection incidence of at least 4.3% and an incidence...

  16. A new technique for long time catheterization of sacral epidural canal in rabbits.

    Science.gov (United States)

    Erkin, Yüksel; Aydın, Zeynep; Taşdöğen, Aydın; Karcı, Ayşe

    2013-01-01

    In this study we aimed to develop a simple and practical technique for chronic sacral epidural catheterization of rabbits. We included ten rabbits weighing 2-2.5 kg in the study. After anesthesia and analgesia, we placed an epidural catheter by a 2 cm longitudinal skin incision in the tail above the sacral hiatus region. We confirmed localization by giving 1% lidocaine (leveling sensory loss and motor function loss of the lower extremity). The catheter was carried forward through a subcutaneous tunnel and fixed at the neck. Chronic caudal epidural catheter placement was succesful in all rabbits. The catheters stayed in place effectively for ten days. We encountered no catheter complications during this period. The localization of the catheter was reconfirmed by 1% lidocaine on the last day. After animals killing, we performed a laminectomy and verified localization of the catheter in the epidural space. Various methods for catheterization of the epidural space in animal models exist in the literature. Epidural catheterization of rabbits can be accomplished by atlanto-occipital, lumbar or caudal routes by amputation of the tail. Intrathecal and epidural catheterization techniques defined in the literature necessitate surgical skill and knowledge of surgical procedures like laminectomy and tail amputation. Our technique does not require substantial surgical skill, anatomical integrity is preserved and malposition of the catheter is not encountered. In conclusion, we suggest that our simple and easily applicable new epidural catheterization technique can be used as a model in experimental animal studies.

  17. Epidural catheter fragment entrapment: a case report

    Directory of Open Access Journals (Sweden)

    Mohammadi M

    2010-07-01

    Full Text Available "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 st1":*{behavior:url(#ieooui } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Epidural catheters are seldom difficult to remove from patients. The breakage of the catheters is uncommon, troublesome and occasionally dangerous. "n"nCase presentation: A lumbar epidural catheter inserted in a 17 year-old man for applying anesthesia for internal fixation of femur fracture and subsequent postoperative epidural analgesia. In the third postoperative day, during unsuccessful attempt for removing the catheter, it was broken and was retained in his back. A CT- scan was performed and shows a fragment of catheter in the sub- laminar ligament between L3 and L4 without any connection with epidural space. As the patient had no complaint the fractured fragment was left in site and he was just followed up in the clinic."n"nConclusion: The knowledge of practical method in locating the retained epidural catheter, and the indication for surgical removal are very important. CT- scan is useful in showing the mechanism and locating the epidural catheter entrapment and facilitating surgical follow-up.

  18. Estudo comparativo entre bupivacaína racêmica (S50-R50 a 0,125% e bupivacaína em excesso enantiomérico de 50% (S75-R25 a 0,125% e 0,25% em anestesia peridural para analgesia de parto Estudio comparativo entre bupivacaina racémica (S50-R50 a 0,125% y bupivacaina en exceso enantiomérico de 50% (S75-R25 a 0,125% y 0,25% en anestesia peridural para analgesia de parto A comparative study of 0.125% racemic bupivacaine (S50-R50 and 0.125% and 0.25% 50% enantiomeric excess bupivacaine (S75-R25 in epidural anesthesia for labor analgesia

    Directory of Open Access Journals (Sweden)

    Nádia Maria da Conceição Duarte

    2008-02-01

    estudio fue comparar la analgesia y el bloqueo motor entre la Bupivacaina (S50-R50 a 0,125% y la Bupivacaina en exceso enantiomérico de 50% (S75-R25 a 0,125% e 0,25% en peridural continua para analgesia de parto. MÉTODO: Se realizó un ensayo clínico doblemente encubierto, con distribución aleatoria de 75 participantes en trabajo de parto, distribuidas en tres grupos: GI - Bupivacaina (S50-R50 a 0,125%, GII - Bupivacaina (S75-R25 a 0,125% y GIII - Bupivacaina (S75-R25 a 0,25%. La inclusión en el estudio fue hecha después de la firma del Consentimiento Libre y Aclarado. RESULTADOS: No se encontraron diferencias estadísticas significativas en cuanto a la latencia de la analgesia, nivel sensorial del bloqueo, volumen de anestésico local, duración del trabajo de parto y de la analgesia, frecuencia de parto instrumental, puntuaciones de Apgar o pH del cordón umbilical. El intervalo para la primera dosis rescate fue mayor y los puntajes de dolor en 45 minutos fueron menores en el grupo Bupivacaina (S75-R25 a 0,25%. La intensidad del bloqueo motor fue mayor en el grupo Bupivacaina (S50-R50 a 0,125%. CONCLUSIONES: La Bupivacaina (S75-R25 determinó un bloqueo motor menos intenso, incluso cuando se utilizó en mayor concentración (0,25%, resultando en una mejor calidad de analgesia, sin interferir en la evolución del trabajo de parto o en la vitalidad de los recién nacidos.BACKGROUND AND OBJECTIVES: Continuous epidural block is used for relief of labor pain and it is associated with a low incidence of complications. Studies with the levorotatory isomer of local anesthetics demonstrated that they are safer regarding the cardiotoxicity. The objective of this study was to compare analgesia and motor blockade of 0.125% bupivacaine (S50-R50 and 0.125% and 0.25% 50% enantiomeric excess bupivacaine (S75-R25 in continuous epidural block for labor analgesia. METHODS: Seventy-five patients in labor participated in this randomized, double-blind study after signing an informed

  19. Incidence of epidural catheter replacement in parturients: a retrospective chart review.

    Science.gov (United States)

    Eappen, S; Blinn, A; Segal, S

    1998-10-01

    We noted in our practice of obstetric anesthesia at a large teaching hospital that the epidural catheter failure rate was higher than previously reported. We undertook this study to determine the incidence of epidural catheter failure in parturients and to determine the primary causes of failure. After institutional approval, we evaluated the charts of parturients who received epidural analgesia for labor or anesthesia for cesarean section for 6 randomly selected months spanning one year. We examined 4240 anesthesia records for patient-related data, operator-related data (years of training) and technical information. The participants were unaware there was a study in progress, and data were collected in a systematic fashion so as to minimize data collection related biases. Chi2, Mantel-Haenszel chi2, analysis of variance and univariate logistic regression were used to analyze data. P<0.05 was considered statistically significant. Overall epidural catheter failure rate was 13.1% with a dural puncture rate of 1.03%. The major causes of catheter failure were no analgesia and unilateral block. The experience of the anesthesiologist, the mode of delivery, patient age, patient weight, type of epidural catheter, occurrence of paresthesia and the use of CSE were all associated with significantly different epidural catheter replacement rates. Despite the initially high failure rate, the overall patient satisfaction rate was greater than 98%.

  20. Effects of lumbosacral epidural ketamine and lidocaine inxylazine-sedated cats : article

    Directory of Open Access Journals (Sweden)

    R. DeRossi

    2009-05-01

    Full Text Available In order to determine the analgesic and cardiovascular effects of the combination of epidural ketamine and lidocaine, 6 sedated cats were studied. Six healthy, young cats were used in a prospective randomised study. Each cat underwent 3 treatments, at least 1 week apart, via epidural injection: (1 ketamine (2.5 mg/kg, (2 lidocaine (4.0 mg/kg, and (3 ketamine (2.5 mg/kg plus lidocaine (4.0 mg/kg. Epidural injections were administered through the lumbosacral space. Analgesia, motor block, sedation, heart rate, arterial blood pressure, respiratory rate and arterial oxygen saturation were measured. Rectal temperature was compared before and after sedation as well as after epidural administration of the drugs. Epidural administration of the ketamine/lidocaine combination induced prolonged analgesia extending from the coccygeal to the T13-L1 dermatomes, leading to severe ataxia. Cardiovascular effects were significant in all treatments: heart rate decreased, but there was a minimal reduction in arterial pressure. It was concluded that adding a dose of ketamine to epidural lidocaine in cats is feasible and effective.

  1. Efeitos cardiovasculares e analgésicos da administração epidural de ropivacaína isolada ou associada à morfina, em felinos

    Directory of Open Access Journals (Sweden)

    Doughlas Regalin

    2014-12-01

    Full Text Available Visando avaliar os efeitos cardiovasculares e analgésicos de dois protocolos epidurais em felinos submetidos à OSH, 16 gatas mestiças, adultas, que, após indução à anestesia geral, receberam anestesia epidural (L7 - S1 com 0,26mL kg-1 de ropivacaína 0,75%, isolada (GR ou associada a 0,1mg kg-1 morfina (GRM. A ETCO2, f, FC, PAS, T°R e relaxamento muscular foram avaliados no momento basal, 30 minutos após epidural, após incisão de pele, ligadura dos pedículos ovarianos e cérvix, final da celiorrafia e cirurgia, sendo administrado fentanil, caso ocorresse aumento de 20% na PAS, FC ou f em relação ao momento basal. Ao final do procedimento, foram avaliados, com auxílio de uma escala multidimensional de dor aguda em felinos, durante 12 horas, e, quando a pontuação fosse ≥8, era realizado resgate analgésico com morfina 0,2mg kg-1. Não ocorreram diferenças entre ETCO2, f, T°C e relaxamento muscular. A PAS aumentou em ambos os grupos durante o pinçamento dos pedículos ovarianos e cérvix, quando 100% dos animais do GR e 87,5% do GRM necessitaram fentanil transoperatório. Em 100% dos animais do GR, houve necessidade de morfina pós-operatória às 2 e 4 horas de avaliação, comparados com 50% e 37,5% no GRM. Nos momentos seguintes aos resgates, o somatório de pontos foi semelhante entre grupos. Conclui-se que a administração epidural de ropivacaína associada à morfina em gatas submetidas à ovariosalpingohisterectomia reduz o requerimento analgésico pós-operatório em até 56,2%, durante as primeiras 4 horas, e promove analgesia adequada durante 12 horas, quando comparado à ropivacaína isolada

  2. Comparison Thoracic Epidural and Intercostal Block to Improve Ventilation Parameters and Reduce Pain in Patients with Multiple Rib Fractures

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    Raheleh Aligholipour Maleki

    2011-08-01

    Full Text Available Introduction: Chest wall blunt trauma causes multiple rib fractures and will often be associated with significant pain and may compromise ventilator mechanics. Analgesia has great roll in rib fracture therapies, opioid are useful, but when used as sole agent may re-quire such high dose that they produce respiratory depression, especially in el-derly .the best analgesia for a severe chest wall injury is a continuous epidural infusion of local anesthetic. This provides complete analgesia allowing inspiration and coughing without of the risk of respiratory depression. Methods: sixty adult patients who with multiple rib fractures were enrolled in this study. They were divided into Group A or thoracic epidural with bupivacaine 0.125 % +1mg/5ml morphine and group B or inter-costal block with %0.25 bupivacaine. The patients were assessed through ICU and hos-pital stay length, ventilation function tests. Pain score among the patients was meas-ured with verbal rating scale, before and after administration of the analgesia. Results: We found a significant improvement in ventilatory function tests during the 1st, 2nd, and 3rd days after epidural analgesia compared with the intercostal block (P < 0.004. Changes in the visual Analogue Scale were associated with marked improvement re-garding pain at rest and pain caused by coughing and deep breathing in group A com-pared group B... ICU and hospital stay markedly reduced in Group A. Conclusion: tho-racic epidural analgesia is superior to intercostals block regarding pain relief of rib frac-tures. Patients who received epidural analgesia had significantly lower pain scores at all studied times.

  3. Spontaneous spinal epidural abscess.

    LENUS (Irish Health Repository)

    Ellanti, P

    2011-10-01

    Spinal epidural abscess is an uncommon entity, the frequency of which is increasing. They occur spontaneously or as a complication of intervention. The classical triad of fever, back pain and neurological symptoms are not always present. High index of suspicion is key to diagnosis. Any delay in diagnosis and treatment can have significant neurological consequences. We present the case of a previously well man with a one month history of back pain resulting from an epidural abscess.

  4. Uso do bloqueio combinado raqui-peridural durante cirurgia de cólon em paciente de alto risco: relato de caso Uso del bloqueo combinado raquiepidural durante cirugía de colon en paciente de alto riesgo: relato de caso Combined spinal epidural anesthesia during colon surgery in a high-risk patient: case report

    Directory of Open Access Journals (Sweden)

    Luiz Eduardo Imbelloni

    2009-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O bloqueio combinado raqui-peridural (BCRP oferece vantagens sobre a anestesia peridural ou subaracnóidea com injeção única. O objetivo deste relato foi apresentar um caso onde a anestesia subaracnóidea segmentar pode ser técnica efetiva para intervenção cirúrgica gastrintestinal com respiração espontânea. RELATO DO CASO: Paciente estado físico ASA III, diabetes mellitus tipo II, com hipertensão arterial sistêmica e doença pulmonar obstrutiva crônica, foi escalada para ressecção de tumor de cólon direito. O BCRP foi realizado no interespaço T5 - T6 e foram injetados 8 mg de bupivacaína a 0,5% isobárica acrescida de 50 µg de morfina no espaço subaracnóideo. O cateter peridural (20G foi introduzido quatro centímetros em direção cefálica. Foi obtida sedação com doses fracionadas de 1 mg de midazolam (total de 6 mg. Bupivacaína a 0,5% foi administrada em bolus de 25 mg através do cateter duas horas após a anestesia subaracnóidea. Não houve necessidade de vasopressor nem atropina. CONCLUSÕES: Este caso proporciona evidências de que a raquianestesia segmentar pode ser uma técnica anestésica para operação gastrintestinal com respiração espontânea.JUSTIFICATIVA Y OBJETIVOS: El bloqueo combinado raquiepidural (BCRE, tiene ventajas sobre la anestesia epidural o subaracnoidea con inyección única. El objetivo de este relato, fue presentar un caso donde la anestesia subaracnoidea segmentaria, puede ser una técnica efectiva para la intervención quirúrgica gastrointestinal con respiración espontánea. RELATO DEL CASO: Paciente estado físico ASA III, diabetes mellitus tipo II, con hipertensión arterial sistémica y enfermedad pulmonar obstructiva crónica, que fue indicada para la resección del tumor de colon derecho. El BCRE se realizó en el interespacio T5 - T6, y se inyectaron 8 mg de bupivacaína a 0,5% isobárica con 50 µg más de morfina en el espacio subaracnoideo. El cat

  5. Effect of patient-controlled epidural analgesia with opioids on serous myelin basic protein and somatosensory evoked potential of lower limbs in puerperants%阿片类药物硬膜外术后镇痛对产妇血清髓鞘碱性蛋白和下肢体感诱发电位的影响

    Institute of Scientific and Technical Information of China (English)

    宋杰; 杜伯祥; 崔志明; 周峰; 杨许丽; 保国峰; 刘麟

    2011-01-01

    Objective To investigate the effect of patient-controlled epidural analgesia(PCEA) with opioids on serous myelin basic protein(MBP) and somatosensory evoked potential(SEP) of lower limbs in puerperants.Methods A total of 120 puerperants,after receiving cesarean section,were divided into four groups by random number table method as group B,BR,MR and R randomly,and each group included 30 cases.After surgery,each case received PCEA:group B received 0.008% butrophanol;group BR received 0.008% butrophanol + 0.2% ropivacaine;group MR received 0.004% morphine +0.2% ropivacaine and group R received 0.2% ropivacaine only.VAS score,OAA/S score,adverse effect occurrence,concentration changes of serous MBP,SEP of both lower limbs and neurological function were observed at 2h(T1 ),4h(T2),8 h(T3),12h(T4),24 h(T5) and 48h (T6) after surgery.Results VASscoresofgroupBR(1.64±0.38,1.86±0.62,1.93±0.67) and MR( 1.74 ±0.39,1.91±0.58,1.98 ±0.63) at T3,T4,T5 were lower than those of group B(4.6 ±0.5,4.6 ±0.3,4.7 ±0.3)and R(2.64 ±0.41,2.83 ±0.91,3.37 ±0.87) (P<0.05).There was no significance in four groups in OAA/S score at each point (P > 0.05 ).Incidence of nausea ( 6 cases),vomiting ( 2 cases) and abdominal distention ( 5cases) of group M was higher than that of other three groups(P<0.05).There was no significant difference in concentrations of serous MBP,SEP and neurological function in all four groups between preoperative time and 48h after operation(P>0.05).Conclusion Lower-dose and lower- concentration opioids used for PCEA have no influence on serum MBP and SEP.%目的 观察阿片类药物用于刮宫产硬膜外术后自控镇痛(Patient-controlled epidural analgesia,PCEA)对血清髓鞘碱性蛋白(myelin basic protein,MBP)和下肢体感诱发电位(somatosensory evoked potential,SEP)的影响.方法 术后行PCEA的剖官产产妇120例,随机数字表法分为4组,每组30例:B组:0.008%布托啡诺;BR组:0.008%布托啡诺+0.2

  6. Estudo comparativo entre anestesia peridural torácica e anestesia geral em mastectomia oncológica Estudio comparativo entre la anestesia epidural torácica y la anestesia general en mastectomia oncológica Comparative study between thoracic epidural block and general anesthesia for oncologic mastectomy

    Directory of Open Access Journals (Sweden)

    Sérgio D. Belzarena

    2008-12-01

    utiliza a menudo para procedimientos estéticos de la mama y existen pocos relatos de su uso en mastectomías con exploración axilar. El presente estudio comparó la técnica con anestesia general en operaciones oncológicas de la mama. MÉTODO: Cuarenta pacientes que se dividieron en dos grupos. En el grupo epidural (n = 20 se hizo una epidural torácica con bupivacaína y fentanil asociados a la sedación con midazolam. El otro grupo (n = 20, recibió anestesia general convencional con propofol, atracurio y fentanil y mantenimiento con O2 e isoflurano. En el intraoperatorio y durante la operación, se verificó la necesidad de complementación de la anestesia o de la sedación y variables hemodinámicas. En el postoperatorio fue registrado el tiempo para el alta de la sala de recuperación postanestésica y hospitalaria, la intensidad del dolor y el consumo de analgésicos, efectos adversos y la satisfacción con la técnica anestésica. RESULTADOS: Los grupos fueron similares y no hubo diferencia en la duración de la operación. Se hizo necesario complementar la sedación en un 100% de las pacientes que recibieron anestesia epidural y en un 15% fue complementada la analgesia con infiltración de anestésico local en la axila. Hubo una mayor incidencia de hipertensión arterial en el grupo de la anestesia general y de hipotensión entre las que recibieron epidural. Ocurrió prurito en un 55% de las pacientes con anestesia epidural. Náusea (30% y vómito (45%, fueron más frecuentes entre las que recibieron anestesia general. La analgesia postoperatoria tuvo una mejor calidad y el consumo de analgésicos fue menor en el grupo de la anestesia epidural. El período de internación también fue menor. CONCLUSIONES: La técnica epidural tiene algunas ventajas con relación a la anestesia general y puede ser considerada una opción para la anestesia en mastectomías oncológicas con vaciado axilar.BACKGROUND AND OBJECTIVES: Thoracic epidural block is frequently used for

  7. Post operatory analgesia in caesarean surgery. Analgesia posoperatoria en la operación cesárea.

    Directory of Open Access Journals (Sweden)

    Rolando T. Espín González

    >Fundamento: El dolor posoperatorio constituye un problema muy difundido y constante en los cuidados del paciente quirúrgico. La lucha por encontrar nuevas terapéuticas para aliviar el dolor ha llevado a la fabricación y uso de gran variedad de analgésicos que son administrados por diferentes vías. Se conocen bien los efectos de los narcóticos en el recién nacido y fue la preocupación al respecto lo que motivó el interés por el uso de esos fármacos por vía epidural e intratecal en la paciente obstétrica. Objetivo: Evaluar la factibilidad del uso de morfina liofilizada por vía peridural en la operación cesárea. Métodos : Estudio de serie de casos desarrollado durante el periodo comprendido entre febrero del 2001 a agosto del 2002 en la unidad quirúrgica del Servicio de Ginecoobstetricia del Hospital Universitario ¨Dr.Gustavo Aldereguía Lima¨ de Cienfuegos, que incluyó 120 pacientes sometidas a cesárea iterativa electiva. Se analizaron variables correspondientes a tensión arterial, frecuencia cardiaca, frecuencia respiratoria durante el preoperatorio, transoperatorio y posoperatorio, comienzo del efecto anestésico y duración de este, además se analizaron las complicaciones perioperatorias, la calidad de la analgesia posoperatoria y su repercusión en el recién nacido, medida mediante el puntaje de Apgar. El procesamiento estadístico se realizó utilizando el paquete estadístico Epi Info 6. Resultados : El comienzo del efecto anestésico y el tiempo de duración de la anestesia no se modificaron con el uso de la morfina liofilizada. Los parámetros vitales se mantuvieron con valores normales en la mayoría de las pacientes durante el preoperatorio, transoperatorio y posoperatorio. Las complicaciones que se presentaron fueron: prurito, retención urinaria, náuseas y vómitos. La calidad de la analgesia resultó satisfactoria en la mayoría de las paciente

  8. Differential blockade to assess surgical repair by intraoperative active mobilization in knee injuries-Beyond labour analgesia

    Directory of Open Access Journals (Sweden)

    G Vijay Anand

    2011-01-01

    Full Text Available Motor-sparing selective epidural analgesia has long been practised in the field of labour analgesia. However, the utility of such techniques in other fields remain limited. We present the successful use of a similar technique of differential blockade in a case of quadriceps plasty with realignment of patella for recurrent dislocation of patella. A very low concentration of bupivacaine and fentanyl was used through continous epidural. The adequacy of repair was assessed intraoperatively by active movement of operated limb by patient himself.

  9. Spinal and Intracranial Epidural Abscess

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2009-03-01

    Full Text Available Presentation, epidemiology, diagnosis and treatment of spinal epidural abscess (SEA and intracranial epidural abscess (ICEA are reviewed by researchers at The John's Hopkins University School of Medicine, Baltimore, MD, and Universidad de Santander, Columbia.

  10. A double-blind comparison between epidural morphine and epidural clonidine in patients with chronic non-cancer pain.

    Science.gov (United States)

    Glynn, C; Dawson, D; Sanders, R

    1988-08-01

    In a randomised double-blind study of 20 patients with chronic pain, epidural morphine 5 mg in 5 ml of saline was compared with epidural clonidine 150 micrograms in 5 ml of saline. Thirteen patients had a clinical and radiological diagnosis of arachnoiditis, 6 had low back pain and 1 had post-operative scar pain. There were 18 females and 2 males with an average age of 52 years, range 22-76 years. There was no difference found between the 2 solutions in the resultant analgesia measured by the visual analogue scale for pain, pain relief or the pain word score during the 3 h period of the study. No difference was found in the patient's mood which was also measured with the visual analogue scale. Two patients had no analgesia from either injection, 2 patients did not obtain any relief from clonidine and another 2 obtained no relief from morphine. Six patients reported that clonidine was better than morphine, 5 reported that morphine and clonidine were the same and 3 reported that morphine was better than clonidine. The duration of analgesia from the clonidine varied from 6 h to 1 month; the duration of analgesia from morphine varied from 6 to 24 h. Clonidine was associated with sedation and a fall in blood pressure of greater than 20 mm Hg in all patients, 1 patient required ephedrine to treat hypotension. Twelve patients had pruritus, 7 nausea and 2 vomiting following the morphine. Statistically there was no difference found between morphine and clonidine for short-term (3 h) analgesia in these patients.(ABSTRACT TRUNCATED AT 250 WORDS)

  11. Evidence for using air or fluid when identifying the epidural space.

    Science.gov (United States)

    Sanford, Curtis L; Rodriguez, Ricardo E; Schmidt, James; Austin, Paul N

    2013-02-01

    Lumbar epidural analgesia is frequently employed to provide pain relief for women during labor. Anesthesia providers use various methods to identify the epidural space. Some providers use air, some use fluid, and others use a combination of air and fluid during the loss of resistance technique. Loss of resistance to air has been speculated to result in a lesser quality of analgesia compared with loss of resistance to only fluid. A search strategy focusing on preappraised sources was used to locate evidence from interventional and observational studies. Four evidence sources were located, including a systematic review with meta-analysis of 4 older studies. The evidence reviewed was inconclusive in determining whether a difference in analgesia quality results from the use of air or fluid during the loss of resistance technique. Future studies should include an adequate number of subjects and address other problems such as operator experience, observer blinding, equivalence of subject characteristics, outcomes definition and measurement, and composition of epidural solution. Providers should consider other factors when selecting loss of resistance medium, such as the reported complications of large amounts of air injected into the epidural space and surrounding structures.

  12. Low-dose spinal neostigmine further enhances the analgesic effect of spinal bupivacaine combined with epidural dexamethasone, following orthopedic surgery

    Directory of Open Access Journals (Sweden)

    Gabriela Rocha Lauretti

    2014-01-01

    Full Text Available Background: Opioids are considered mainstream for combined spinal-epidural anesthesia, but frequently limited by adverse effects. The aim of this study was to examine whether low-dose spinal neostigmine, epidural dexamethasone or their combination enhances analgesia from spinal bupivacaine without adverse effects. Materials and Methods : A total of 60 patients undergoing orthopedic surgery were randomized to one of four groups and evaluated for 24-h after surgery for analgesia (time to first rescue analgesic and rescue analgesic consumption. Patients received 15 mg bupivacaine plus the test drug intrathecally (saline or 1 microgram (μg neostigmine. The epidural test drug was either saline or 10 mg dexamethasone. The Control group (CG received spinal and epidural saline. The Neostigmine group (NG, spinal neostigmine and epidural saline; the Dexamethasone group (DG, spinal saline and epidural dexamethasone; and the Neostigmine-dexamethasone group (NDG, spinal neostigmine and epidural dexamethasone. Results: The CG (282 ± 163 min and NG (524 ± 142 min were similar in their times to first rescue analgesic and analgesic consumption. The time to first rescue analgesic was longer for the DG (966 ± 397 min compared with CG and NG (P < 0.0002, and the DG had less ketoprofen consumption and lower overall visual analogue scale-pain sores compared with CG and NG (P < 0.0005. Addition of 1 mg-neostigmine (NDG resulted in longer time to rescue analgesic (1205 ± 303 min; P < 0.02 and lower ketoprofen consumption (P < 0.05 compared to DG. Sporadic cases of vesical catheterization and emesis were observed, however adverse effects were similar among groups. Conclusion: Spinal 1 microgram (μg neostigmine further enhanced analgesia from spinal bupivacaine combined with epidural dexamethasone, without increasing the incidence of adverse effects.

  13. The effect of balanced analgesia on early convalescence after major orthopaedic surgery

    DEFF Research Database (Denmark)

    Møiniche, S; Hjortsø, N C; Hansen, B L;

    1994-01-01

    Forty-two patients scheduled for total knee arthroplasty (n = 20) or hip arthroplasty (n = 22) were randomly allocated to receive either continuous epidural bupivacaine/morphine for 48 h postoperatively plus oral piroxicam, or general anaesthesia followed by a conventional intramuscular opioid...... and acetaminophen regimen. Patients undergoing knee- or hip arthroplasty treated with epidural analgesia had significantly lower pain scores during mobilization under the 48 h epidural infusion compared with patients receiving conventional treatment, while no important differences were observed after cessation...... of the epidural regimen. However, the achieved pain relief had no impact on postoperative convalescence parameters, such as ambulation, patient activity including need for nursing care, fatigue or hospital stay. Late postoperative pain, fatigue and conservative attitudes and routines in the postoperative care...

  14. Tratamiento epidural del dolor en isquemia vascular periférica: Parte II. Revisión bibliográfica basada en la evidencia del tratamiento epidural en la isquemia vascular periférica Epidural pain treatment in peripheral vascular ischemia: (II

    Directory of Open Access Journals (Sweden)

    M.J. Orduña González

    2009-04-01

    Full Text Available Introducción: La isquemia arterial periférica puede ser el resultado de diversas enfermedades que afectan la vascularización de los miembros, generando dolor, discapacidad y deterioro de la calidad de vida del paciente, y en los casos de isquemia crítica, produciendo una considerable morbimortalidad y dolor crónico. Objetivo: Realizar una revisión histórica y crítica de publicaciones científicas sobre la analgesia epidural como método de control del dolor por isquemia vascular periférica y de sus efectos tróficos vasculares, y compararlos con otras técnicas analgésicas, así como recopilar diversas pautas de analgesia epidural y sus resultados. Material y métodos: Búsqueda en Medline, recopilación de datos y posterior análisis crítico, siguiendo los criterios de la medicina basada en la evidencia, de las publicaciones científicas sobre analgesia epidural y el dolor en el contexto de la isquemia arterial periférica. Resultados: a La analgesia con infusión de fármacos epidurales en isquemia de miembros sólo alcanzó un nivel de evidencia 4 en la presente revisión; b la anestesia epidural lumbar para cirugía de revascularización de miembros inferiores se relaciona con unas menores tasas de trombosis postoperatoria y de reintervenciones de revascularización que la anestesia general (nivel de evidencia 2b; c no hay evidencia científica concluyente que apoye la utilización de analgesia epidural preventiva de los síndromes de dolor crónico postamputación de extremidades con isquemia, y d la aplicación de neuroestimulación epidural medular en la isquemia crítica de origen ateroclusivo de miembros no reconstruibles mediante técnicas quirúrgicas está apoyada por un nivel de evidencia 1. En la enfermedad de Buerger, la enfermedad de Raynaud y trastornos vasoespásticos, la aplicación de la neuroestimulación eléctrica epidural viene avalada por un nivel de evidencia 4. Conclusiones: a La isquemia arterial perif

  15. Analgesia after total hip replacement: epidural versus psoas ...

    African Journals Online (AJOL)

    cessfully for hip replacement surgery.7 They were the first to call this approach the ... block is the technique of choice due to a better risk profile.13 In a later study .... necessitating treatment by the nursing staff occurred in three of the patients in ...

  16. A comparison of epidural anaesthesia with lignocaine, bupivacaine and a lignocaine-bupivacaine mixture in cats

    Directory of Open Access Journals (Sweden)

    F.M. Lawal

    2009-05-01

    Full Text Available A mixture of 2% lignocaine (LIG and 0.5% bupivacaine (BUP, at respective dose rates of 2 mg/kg and 0.5 mg/kg (LIG-BUP, was compared to LIG (4 mg/kg and BUP (1 mg/kg for lumbosacral epidural anaesthesia in 5 sedated cats. Each cat received all 3 treatment regimens at 1-week intervals. The cats were premedicated with an intramuscular injection of atropine sulphate (0.04 mg/kg and ketamine hydrochloride (10 mg/kg. Onset and duration of analgesia, and time to walking were determined. Associated changes in heart rate (HR, respiratory frequency (ƒR and rectal temperature (RT were recorded. Onset of analgesia with epidurally administered LIG-BUP (4.5 ± 0.7 min, LIG (3.9 ± 1.0 min and BUP (5.0 ± 1.0 min was similar. Duration of analgesia with LIG-BUP (49.4 ± 4.5 min was significantly (P < 0.05 longer than with LIG (40.2 ± 1.0 min but shorter than with BUP (79.4 ± 6.3 min. There were no significant differences in times to standing with LIG-BUP (26.3 ± 6.4 min, LIG (20.4 ± 4.7 min and BUP (22.6 ± 10.3 min. Minimal changes were observed in HR, ƒR and RT. In conclusion, duration of analgesia produced by LIG-BUP was shorter compared with BUP but longer compared with LIG. Neither LIG nor LIG-BUP has any advantage over epidural BUP in terms of onset of analgesia, time to standing and physiological responses. Therefore, lumbosacral epidural administration of BUP appears to be the best choice for a long surgical procedure lasting more than 1 hour when compared with either LIG or LIG-BUP.

  17. ADMINISTRAÇÃO EPIDURAL DE OPIÓIDES EM CÃES EPIDURAL OPIOIDS ADMINISTRATION IN DOGS

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    Carlos Augusto Araújo Valadão

    2002-04-01

    Full Text Available Os opióides têm sido utilizados em Medicina Veterinária há vários anos como alterna